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Does TRCmatch works with DNN #48

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saramoein372 opened this issue Aug 14, 2023 · 2 comments
Open

Does TRCmatch works with DNN #48

saramoein372 opened this issue Aug 14, 2023 · 2 comments

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@saramoein372
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Hello,

I have a question about TCRmatch: does TCRmatch works based on deep neural network for peptide prediction?

Thanks,
Sara

@raphaeltrevizani
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Hi Sara.
TCRMatch is not based on DNN for peptide prediction. It uses a sequence similarity k-mer approach matching the query to the CDR3b sequences in the IEDB database to predict whether a given TCR sequence is likely to recognize a specific peptide as an epitope.

@saramoein372
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saramoein372 commented Aug 15, 2023 via email

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