Usage with SQLachmey or SQLModel and Alembic

[joshwisehub]

how do i use with ORM like sqlachemy or sqlmodel.I need to define a user which will have cv as as uploadel file and profile_picture as uploaded image.How do we define the reposponse models in the route and if i need to set crud operation in a separate file so to make the api route a little bit clean.An for the case of null values if i need to make the cv or profile picture null.If you have any guide please provide your sample implementation.