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Network and Functional Analysis of Ece1p-Human Interactome for Target Identification

Code for Visualization and analysis of Ece1p(C. albicans)-Human interactome.

The analysis code can be found in the Code/ folder.

  1. Number of interacting host genes of each peptide.py
  2. Significance of peptide overlap.py
  3. Cellular localization of peptide-interacting host proteins.py
  4. bar-overlap.R
  5. upset-gene.R
  6. bar-GOenrichment.R
  7. bar-GOenrichment-metascape.R

Bioinformatics analysis in paper "Global fungal-host interactome mapping identifies targets of candidalysin" were implemented by code above.

Screening results of HT-eY2H

The 2nd screening results of HT-eY2H can be found in Final list of genes for all peptides.xlsx.