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[Feature] Cluster significance testing using sc-SHC #5

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MicTott opened this issue Feb 12, 2024 · 0 comments
Open

[Feature] Cluster significance testing using sc-SHC #5

MicTott opened this issue Feb 12, 2024 · 0 comments

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@MicTott
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MicTott commented Feb 12, 2024

As @boyiguo1 suggested, we could potentially implement cluster significance testing using sc-HSC to determine which samples have artifacts.

After a quick glance, it seems like sc-HSC offers two possible solutions: 1) use their hierarchical clustering function scSHC to cluster out artifacts in PCA space, or 2) continue to use k-means/GMM and then use the their significance testing function testClusters to either accept or reject the cluster results.

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