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Add option for regressing out cycling, mitochondrial and ribosomal influences #41

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nictru opened this issue Feb 16, 2024 · 3 comments
Open

Add option for regressing out cycling, mitochondrial and ribosomal influences #41

nictru opened this issue Feb 16, 2024 · 3 comments
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enhancement New feature or request
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nictru commented Feb 16, 2024 •
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During the Edinburgh STSM we discovered that mitochondrial and ribosomal genes show up more often than expected in the differential expression results.
@nictru nictru self-assigned this Feb 16, 2024
@nictru nictru added the enhancement New feature or request label Feb 16, 2024
@nictru nictru added this to the Budva milestone Feb 16, 2024
@nictru nictru changed the title Exclude certain genes from neighborhood graph calculation Add option for regressing out mitochondrial and ribosomal influences Feb 16, 2024
@nictru nictru changed the title Add option for regressing out mitochondrial and ribosomal influences Add option for regressing out cycling, mitochondrial and ribosomal influences Feb 16, 2024
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nictru commented Feb 16, 2024 •
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We should keep in mind, that we might lose some biological information through this

@FPetitprez
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We should keep in mind, that we might lose some biological information through this

Perhaps this would make more sense in the subsetted atlases only?

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nictru commented Feb 16, 2024

Yes, could be part of #42

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