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qt6u*HAM8EAe+c>i|2rVpYAfdE$e?1bumfoya9NmInGlRT?*9)G23J}D literal 0 HcmV?d00001 diff --git a/slide_dge.Rmd b/slide_dge.Rmd index cd79c8a4..1a0e9e65 100644 --- a/slide_dge.Rmd +++ b/slide_dge.Rmd @@ -70,6 +70,22 @@ name: intro - Advanced designs +--- +name: intro2 + +## Couldn’t we just use a Student’s t test for each gene? + + +```{r, echo=FALSE, out.width="30%", fig.align='center'} +knitr::include_graphics("data/boxplot.png") +``` + +- May have few replicates -> "borrow" information from other genes +- Multiple testing issues -> Correction +- Distribution is not normal -> negative binomial methods + + + --- name: prep