diff --git a/PioneerWatchfulWaiting/changeLog.Rmd b/PioneerWatchfulWaiting/changeLog.Rmd index 103c1b9a..e57515d3 100644 --- a/PioneerWatchfulWaiting/changeLog.Rmd +++ b/PioneerWatchfulWaiting/changeLog.Rmd @@ -21,5 +21,8 @@ Now showing task #3 results from 8 databases with correct time-to-event data. ## 2021-Apr-30: Adding pre-task#4 results Now showing results for pre-task#4 for 7 databases. +## 2021-Jul-15: Adding task #5 results & bug fixes +Now shoing results for task #5 for 5 databases. +Some bug fixed from the previous version. ------ diff --git a/PioneerWatchfulWaiting/changeLog.html b/PioneerWatchfulWaiting/changeLog.html index 8e3e2477..f44d0b8d 100644 --- a/PioneerWatchfulWaiting/changeLog.html +++ b/PioneerWatchfulWaiting/changeLog.html @@ -81,6 +81,12 @@

2021-Apr-30: Data Update and Correction

+
+

2021-Jul-15: Adding task #5 results & bug fixes

+

Now shoing results for task #5 for 5 databases. Some bug fixed from the previous version.

+
+
+ diff --git a/PioneerWatchfulWaiting/cohortXref.csv b/PioneerWatchfulWaiting/cohortXref.csv index 75207445..bb3dc66f 100644 --- a/PioneerWatchfulWaiting/cohortXref.csv +++ b/PioneerWatchfulWaiting/cohortXref.csv @@ -1,1387 +1,1621 @@ cohortId,targetId,targetName,strataId,strataName,cohortType -101,101,[T1] Newly diagnosed Pca ,0,All,Target -102,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),0,All,Target -103,103,[T2] PCa treated right away,0,All,Target -104,104,[T2a] PCa treated right away (biopsy or PSA GT 50),0,All,Target -105,105,[T3] PCa under conservative management,0,All,Target -106,106,[T3.1] PCa high/intermediate risk conservative management,0,All,Target -107,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),0,All,Target -108,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,0,All,Target -109,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),0,All,Target -110,110,[T3.3] PCa low risk grade conservative management and intense monitoring,0,All,Target -111,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),0,All,Target -112,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),0,All,Target -113,113,[T4] PCa treated after conservative management ,0,All,Target -114,114,[T4.1] Delayed Curative Management,0,All,Target -115,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),0,All,Target -116,116,[T4.2] Delayed Palliative Management,0,All,Target -117,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),0,All,Target -118,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),0,All,Target -101003012,101,[T1] Newly diagnosed Pca ,301,without High-Risk,TwoS -102003012,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),301,without High-Risk,TwoS -103003012,103,[T2] PCa treated right away,301,without High-Risk,TwoS -104003012,104,[T2a] PCa treated right away (biopsy or PSA GT 50),301,without High-Risk,TwoS -105003012,105,[T3] PCa under conservative management,301,without High-Risk,TwoS -106003012,106,[T3.1] PCa high/intermediate risk conservative management,301,without High-Risk,TwoS -107003012,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),301,without High-Risk,TwoS -108003012,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,301,without High-Risk,TwoS -109003012,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),301,without High-Risk,TwoS -110003012,110,[T3.3] PCa low risk grade conservative management and intense monitoring,301,without High-Risk,TwoS -111003012,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),301,without High-Risk,TwoS -112003012,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),301,without High-Risk,TwoS -113003012,113,[T4] PCa treated after conservative management ,301,without High-Risk,TwoS -114003012,114,[T4.1] Delayed Curative Management,301,without High-Risk,TwoS -115003012,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),301,without High-Risk,TwoS -116003012,116,[T4.2] Delayed Palliative Management,301,without High-Risk,TwoS -117003012,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),301,without High-Risk,TwoS -118003012,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),301,without High-Risk,TwoS -101003022,101,[T1] Newly diagnosed Pca ,302,without Low-Risk,TwoS -102003022,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),302,without Low-Risk,TwoS -103003022,103,[T2] PCa treated right away,302,without Low-Risk,TwoS -104003022,104,[T2a] PCa treated right away (biopsy or PSA GT 50),302,without Low-Risk,TwoS -105003022,105,[T3] PCa under conservative management,302,without Low-Risk,TwoS -106003022,106,[T3.1] PCa high/intermediate risk conservative management,302,without Low-Risk,TwoS -107003022,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),302,without Low-Risk,TwoS -108003022,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,302,without Low-Risk,TwoS -109003022,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),302,without Low-Risk,TwoS -110003022,110,[T3.3] PCa low risk grade conservative management and intense monitoring,302,without Low-Risk,TwoS -111003022,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),302,without Low-Risk,TwoS -112003022,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),302,without Low-Risk,TwoS -113003022,113,[T4] PCa treated after conservative management ,302,without Low-Risk,TwoS -114003022,114,[T4.1] Delayed Curative Management,302,without Low-Risk,TwoS -115003022,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),302,without Low-Risk,TwoS -116003022,116,[T4.2] Delayed Palliative Management,302,without Low-Risk,TwoS -117003022,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),302,without Low-Risk,TwoS -118003022,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),302,without Low-Risk,TwoS -101003032,101,[T1] Newly diagnosed Pca ,303,without Intermediate-Risk,TwoS -102003032,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),303,without Intermediate-Risk,TwoS -103003032,103,[T2] PCa treated right away,303,without Intermediate-Risk,TwoS -104003032,104,[T2a] PCa treated right away (biopsy or PSA GT 50),303,without Intermediate-Risk,TwoS -105003032,105,[T3] PCa under conservative management,303,without Intermediate-Risk,TwoS -106003032,106,[T3.1] PCa high/intermediate risk conservative management,303,without Intermediate-Risk,TwoS -107003032,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),303,without Intermediate-Risk,TwoS -108003032,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,303,without Intermediate-Risk,TwoS -109003032,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),303,without Intermediate-Risk,TwoS -110003032,110,[T3.3] PCa low risk grade conservative management and intense monitoring,303,without Intermediate-Risk,TwoS -111003032,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),303,without Intermediate-Risk,TwoS -112003032,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),303,without Intermediate-Risk,TwoS -113003032,113,[T4] PCa treated after conservative management ,303,without Intermediate-Risk,TwoS -114003032,114,[T4.1] Delayed Curative Management,303,without Intermediate-Risk,TwoS -115003032,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),303,without Intermediate-Risk,TwoS -116003032,116,[T4.2] Delayed Palliative Management,303,without Intermediate-Risk,TwoS -117003032,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),303,without Intermediate-Risk,TwoS -118003032,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),303,without Intermediate-Risk,TwoS -101003042,101,[T1] Newly diagnosed Pca ,304,without Metastatic Dx Extent,TwoS -102003042,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),304,without Metastatic Dx Extent,TwoS -103003042,103,[T2] PCa treated right away,304,without Metastatic Dx Extent,TwoS -104003042,104,[T2a] PCa treated right away (biopsy or PSA GT 50),304,without Metastatic Dx Extent,TwoS -105003042,105,[T3] PCa under conservative management,304,without Metastatic Dx Extent,TwoS -106003042,106,[T3.1] PCa high/intermediate risk conservative management,304,without Metastatic Dx Extent,TwoS -107003042,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),304,without Metastatic Dx Extent,TwoS -108003042,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,304,without Metastatic Dx Extent,TwoS -109003042,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),304,without Metastatic Dx Extent,TwoS -110003042,110,[T3.3] PCa low risk grade conservative management and intense monitoring,304,without Metastatic Dx Extent,TwoS -111003042,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),304,without Metastatic Dx Extent,TwoS -112003042,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),304,without Metastatic Dx Extent,TwoS -113003042,113,[T4] PCa treated after conservative management ,304,without Metastatic Dx Extent,TwoS -114003042,114,[T4.1] Delayed Curative Management,304,without Metastatic Dx Extent,TwoS -115003042,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),304,without Metastatic Dx Extent,TwoS -116003042,116,[T4.2] Delayed Palliative Management,304,without Metastatic Dx Extent,TwoS -117003042,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),304,without Metastatic Dx Extent,TwoS -118003042,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),304,without Metastatic Dx Extent,TwoS -101003052,101,[T1] Newly diagnosed Pca ,305,without Locally advanced Dx Extent,TwoS -102003052,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),305,without Locally advanced Dx Extent,TwoS -103003052,103,[T2] PCa treated right away,305,without Locally advanced Dx Extent,TwoS -104003052,104,[T2a] PCa treated right away (biopsy or PSA GT 50),305,without Locally advanced Dx Extent,TwoS -105003052,105,[T3] PCa under conservative management,305,without Locally advanced Dx Extent,TwoS -106003052,106,[T3.1] PCa high/intermediate risk conservative management,305,without Locally advanced Dx Extent,TwoS -107003052,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),305,without Locally advanced Dx Extent,TwoS -108003052,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,305,without Locally advanced Dx Extent,TwoS -109003052,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),305,without Locally advanced Dx Extent,TwoS -110003052,110,[T3.3] PCa low risk grade conservative management and intense monitoring,305,without Locally advanced Dx Extent,TwoS -111003052,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),305,without Locally advanced Dx Extent,TwoS -112003052,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),305,without Locally advanced Dx Extent,TwoS -113003052,113,[T4] PCa treated after conservative management ,305,without Locally advanced Dx Extent,TwoS -114003052,114,[T4.1] Delayed Curative Management,305,without Locally advanced Dx Extent,TwoS -115003052,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),305,without Locally advanced Dx Extent,TwoS -116003052,116,[T4.2] Delayed Palliative Management,305,without Locally advanced Dx Extent,TwoS -117003052,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),305,without Locally advanced Dx Extent,TwoS -118003052,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),305,without Locally advanced Dx Extent,TwoS -101003062,101,[T1] Newly diagnosed Pca ,306,without Localized Dx Extent,TwoS -102003062,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),306,without Localized Dx Extent,TwoS -103003062,103,[T2] PCa treated right away,306,without Localized Dx Extent,TwoS -104003062,104,[T2a] PCa treated right away (biopsy or PSA GT 50),306,without Localized Dx Extent,TwoS -105003062,105,[T3] PCa under conservative management,306,without Localized Dx Extent,TwoS -106003062,106,[T3.1] PCa high/intermediate risk conservative management,306,without Localized Dx Extent,TwoS -107003062,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),306,without Localized Dx Extent,TwoS -108003062,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,306,without Localized Dx Extent,TwoS -109003062,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),306,without Localized Dx Extent,TwoS -110003062,110,[T3.3] PCa low risk grade conservative management and intense monitoring,306,without Localized Dx Extent,TwoS -111003062,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),306,without Localized Dx Extent,TwoS -112003062,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),306,without Localized Dx Extent,TwoS -113003062,113,[T4] PCa treated after conservative management ,306,without Localized Dx Extent,TwoS -114003062,114,[T4.1] Delayed Curative Management,306,without Localized Dx Extent,TwoS -115003062,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),306,without Localized Dx Extent,TwoS -116003062,116,[T4.2] Delayed Palliative Management,306,without Localized Dx Extent,TwoS -117003062,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),306,without Localized Dx Extent,TwoS -118003062,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),306,without Localized Dx Extent,TwoS -101003072,101,[T1] Newly diagnosed Pca ,307,without PSA greater than 20,TwoS -102003072,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),307,without PSA greater than 20,TwoS -103003072,103,[T2] PCa treated right away,307,without PSA greater than 20,TwoS -104003072,104,[T2a] PCa treated right away (biopsy or PSA GT 50),307,without PSA greater than 20,TwoS -105003072,105,[T3] PCa under conservative management,307,without PSA greater than 20,TwoS -106003072,106,[T3.1] PCa high/intermediate risk conservative management,307,without PSA greater than 20,TwoS -107003072,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),307,without PSA greater than 20,TwoS -108003072,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,307,without PSA greater than 20,TwoS -109003072,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),307,without PSA greater than 20,TwoS -110003072,110,[T3.3] PCa low risk grade conservative management and intense monitoring,307,without PSA greater than 20,TwoS -111003072,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),307,without PSA greater than 20,TwoS -112003072,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),307,without PSA greater than 20,TwoS -113003072,113,[T4] PCa treated after conservative management ,307,without PSA greater than 20,TwoS -114003072,114,[T4.1] Delayed Curative Management,307,without PSA greater than 20,TwoS -115003072,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),307,without PSA greater than 20,TwoS -116003072,116,[T4.2] Delayed Palliative Management,307,without PSA greater than 20,TwoS -117003072,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),307,without PSA greater than 20,TwoS -118003072,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),307,without PSA greater than 20,TwoS -101003082,101,[T1] Newly diagnosed Pca ,308,without PSA less than 10,TwoS -102003082,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),308,without PSA less than 10,TwoS -103003082,103,[T2] PCa treated right away,308,without PSA less than 10,TwoS -104003082,104,[T2a] PCa treated right away (biopsy or PSA GT 50),308,without PSA less than 10,TwoS -105003082,105,[T3] PCa under conservative management,308,without PSA less than 10,TwoS -106003082,106,[T3.1] PCa high/intermediate risk conservative management,308,without PSA less than 10,TwoS -107003082,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),308,without PSA less than 10,TwoS -108003082,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,308,without PSA less than 10,TwoS -109003082,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),308,without PSA less than 10,TwoS -110003082,110,[T3.3] PCa low risk grade conservative management and intense monitoring,308,without PSA less than 10,TwoS -111003082,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),308,without PSA less than 10,TwoS -112003082,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),308,without PSA less than 10,TwoS -113003082,113,[T4] PCa treated after conservative management ,308,without PSA less than 10,TwoS -114003082,114,[T4.1] Delayed Curative Management,308,without PSA less than 10,TwoS -115003082,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),308,without PSA less than 10,TwoS -116003082,116,[T4.2] Delayed Palliative Management,308,without PSA less than 10,TwoS -117003082,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),308,without PSA less than 10,TwoS -118003082,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),308,without PSA less than 10,TwoS -101003092,101,[T1] Newly diagnosed Pca ,309,without PSA 10-20,TwoS -102003092,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),309,without PSA 10-20,TwoS -103003092,103,[T2] PCa treated right away,309,without PSA 10-20,TwoS -104003092,104,[T2a] PCa treated right away (biopsy or PSA GT 50),309,without PSA 10-20,TwoS -105003092,105,[T3] PCa under conservative management,309,without PSA 10-20,TwoS -106003092,106,[T3.1] PCa high/intermediate risk conservative management,309,without PSA 10-20,TwoS -107003092,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),309,without PSA 10-20,TwoS -108003092,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,309,without PSA 10-20,TwoS -109003092,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),309,without PSA 10-20,TwoS -110003092,110,[T3.3] PCa low risk grade conservative management and intense monitoring,309,without PSA 10-20,TwoS -111003092,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),309,without PSA 10-20,TwoS -112003092,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),309,without PSA 10-20,TwoS -113003092,113,[T4] PCa treated after conservative management ,309,without PSA 10-20,TwoS -114003092,114,[T4.1] Delayed Curative Management,309,without PSA 10-20,TwoS -115003092,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),309,without PSA 10-20,TwoS -116003092,116,[T4.2] Delayed Palliative Management,309,without PSA 10-20,TwoS -117003092,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),309,without PSA 10-20,TwoS -118003092,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),309,without PSA 10-20,TwoS -101003102,101,[T1] Newly diagnosed Pca ,310,without Stage T1,TwoS -102003102,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),310,without Stage T1,TwoS -103003102,103,[T2] PCa treated right away,310,without Stage T1,TwoS -104003102,104,[T2a] PCa treated right away (biopsy or PSA GT 50),310,without Stage T1,TwoS -105003102,105,[T3] PCa under conservative management,310,without Stage T1,TwoS -106003102,106,[T3.1] PCa high/intermediate risk conservative management,310,without Stage T1,TwoS -107003102,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),310,without Stage T1,TwoS -108003102,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,310,without Stage T1,TwoS -109003102,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),310,without Stage T1,TwoS -110003102,110,[T3.3] PCa low risk grade conservative management and intense monitoring,310,without Stage T1,TwoS -111003102,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),310,without Stage T1,TwoS -112003102,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),310,without Stage T1,TwoS -113003102,113,[T4] PCa treated after conservative management ,310,without Stage T1,TwoS -114003102,114,[T4.1] Delayed Curative Management,310,without Stage T1,TwoS -115003102,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),310,without Stage T1,TwoS -116003102,116,[T4.2] Delayed Palliative Management,310,without Stage T1,TwoS -117003102,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),310,without Stage T1,TwoS -118003102,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),310,without Stage T1,TwoS -101003112,101,[T1] Newly diagnosed Pca ,311,without Stage T2,TwoS -102003112,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),311,without Stage T2,TwoS -103003112,103,[T2] PCa treated right away,311,without Stage T2,TwoS -104003112,104,[T2a] PCa treated right away (biopsy or PSA GT 50),311,without Stage T2,TwoS -105003112,105,[T3] PCa under conservative management,311,without Stage T2,TwoS -106003112,106,[T3.1] PCa high/intermediate risk conservative management,311,without Stage T2,TwoS -107003112,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),311,without Stage T2,TwoS -108003112,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,311,without Stage T2,TwoS -109003112,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),311,without Stage T2,TwoS -110003112,110,[T3.3] PCa low risk grade conservative management and intense monitoring,311,without Stage T2,TwoS -111003112,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),311,without Stage T2,TwoS -112003112,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),311,without Stage T2,TwoS -113003112,113,[T4] PCa treated after conservative management ,311,without Stage T2,TwoS -114003112,114,[T4.1] Delayed Curative Management,311,without Stage T2,TwoS -115003112,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),311,without Stage T2,TwoS -116003112,116,[T4.2] Delayed Palliative Management,311,without Stage T2,TwoS -117003112,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),311,without Stage T2,TwoS -118003112,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),311,without Stage T2,TwoS -101003122,101,[T1] Newly diagnosed Pca ,312,without Stage T3 or T4,TwoS -102003122,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),312,without Stage T3 or T4,TwoS -103003122,103,[T2] PCa treated right away,312,without Stage T3 or T4,TwoS -104003122,104,[T2a] PCa treated right away (biopsy or PSA GT 50),312,without Stage T3 or T4,TwoS -105003122,105,[T3] PCa under conservative management,312,without Stage T3 or T4,TwoS -106003122,106,[T3.1] PCa high/intermediate risk conservative management,312,without Stage T3 or T4,TwoS -107003122,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),312,without Stage T3 or T4,TwoS -108003122,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,312,without Stage T3 or T4,TwoS -109003122,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),312,without Stage T3 or T4,TwoS -110003122,110,[T3.3] PCa low risk grade conservative management and intense monitoring,312,without Stage T3 or T4,TwoS -111003122,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),312,without Stage T3 or T4,TwoS -112003122,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),312,without Stage T3 or T4,TwoS -113003122,113,[T4] PCa treated after conservative management ,312,without Stage T3 or T4,TwoS -114003122,114,[T4.1] Delayed Curative Management,312,without Stage T3 or T4,TwoS -115003122,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),312,without Stage T3 or T4,TwoS -116003122,116,[T4.2] Delayed Palliative Management,312,without Stage T3 or T4,TwoS -117003122,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),312,without Stage T3 or T4,TwoS -118003122,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),312,without Stage T3 or T4,TwoS -101003132,101,[T1] Newly diagnosed Pca ,313,without Physical Therapy,TwoS -102003132,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),313,without Physical Therapy,TwoS -103003132,103,[T2] PCa treated right away,313,without Physical Therapy,TwoS -104003132,104,[T2a] PCa treated right away (biopsy or PSA GT 50),313,without Physical Therapy,TwoS -105003132,105,[T3] PCa under conservative management,313,without Physical Therapy,TwoS -106003132,106,[T3.1] PCa high/intermediate risk conservative management,313,without Physical Therapy,TwoS -107003132,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),313,without Physical Therapy,TwoS -108003132,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,313,without Physical Therapy,TwoS -109003132,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),313,without Physical Therapy,TwoS -110003132,110,[T3.3] PCa low risk grade conservative management and intense monitoring,313,without Physical Therapy,TwoS -111003132,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),313,without Physical Therapy,TwoS -112003132,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),313,without Physical Therapy,TwoS -113003132,113,[T4] PCa treated after conservative management ,313,without Physical Therapy,TwoS -114003132,114,[T4.1] Delayed Curative Management,313,without Physical Therapy,TwoS -115003132,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),313,without Physical Therapy,TwoS -116003132,116,[T4.2] Delayed Palliative Management,313,without Physical Therapy,TwoS -117003132,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),313,without Physical Therapy,TwoS -118003132,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),313,without Physical Therapy,TwoS -101003142,101,[T1] Newly diagnosed Pca ,314,without Grade 1 (GS 2-6),TwoS -102003142,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),314,without Grade 1 (GS 2-6),TwoS -103003142,103,[T2] PCa treated right away,314,without Grade 1 (GS 2-6),TwoS -104003142,104,[T2a] PCa treated right away (biopsy or PSA GT 50),314,without Grade 1 (GS 2-6),TwoS -105003142,105,[T3] PCa under conservative management,314,without Grade 1 (GS 2-6),TwoS -106003142,106,[T3.1] PCa high/intermediate risk conservative management,314,without Grade 1 (GS 2-6),TwoS -107003142,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),314,without Grade 1 (GS 2-6),TwoS -108003142,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,314,without Grade 1 (GS 2-6),TwoS -109003142,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),314,without Grade 1 (GS 2-6),TwoS -110003142,110,[T3.3] PCa low risk grade conservative management and intense monitoring,314,without Grade 1 (GS 2-6),TwoS -111003142,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),314,without Grade 1 (GS 2-6),TwoS -112003142,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),314,without Grade 1 (GS 2-6),TwoS -113003142,113,[T4] PCa treated after conservative management ,314,without Grade 1 (GS 2-6),TwoS -114003142,114,[T4.1] Delayed Curative Management,314,without Grade 1 (GS 2-6),TwoS -115003142,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),314,without Grade 1 (GS 2-6),TwoS -116003142,116,[T4.2] Delayed Palliative Management,314,without Grade 1 (GS 2-6),TwoS -117003142,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),314,without Grade 1 (GS 2-6),TwoS -118003142,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),314,without Grade 1 (GS 2-6),TwoS -101003152,101,[T1] Newly diagnosed Pca ,315,without Grade 2 (GS 7 (3+4)),TwoS -102003152,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),315,without Grade 2 (GS 7 (3+4)),TwoS -103003152,103,[T2] PCa treated right away,315,without Grade 2 (GS 7 (3+4)),TwoS -104003152,104,[T2a] PCa treated right away (biopsy or PSA GT 50),315,without Grade 2 (GS 7 (3+4)),TwoS -105003152,105,[T3] PCa under conservative management,315,without Grade 2 (GS 7 (3+4)),TwoS -106003152,106,[T3.1] PCa high/intermediate risk conservative management,315,without Grade 2 (GS 7 (3+4)),TwoS -107003152,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),315,without Grade 2 (GS 7 (3+4)),TwoS -108003152,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,315,without Grade 2 (GS 7 (3+4)),TwoS -109003152,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),315,without Grade 2 (GS 7 (3+4)),TwoS -110003152,110,[T3.3] PCa low risk grade conservative management and intense monitoring,315,without Grade 2 (GS 7 (3+4)),TwoS -111003152,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),315,without Grade 2 (GS 7 (3+4)),TwoS -112003152,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),315,without Grade 2 (GS 7 (3+4)),TwoS -113003152,113,[T4] PCa treated after conservative management ,315,without Grade 2 (GS 7 (3+4)),TwoS -114003152,114,[T4.1] Delayed Curative Management,315,without Grade 2 (GS 7 (3+4)),TwoS -115003152,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),315,without Grade 2 (GS 7 (3+4)),TwoS -116003152,116,[T4.2] Delayed Palliative Management,315,without Grade 2 (GS 7 (3+4)),TwoS -117003152,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),315,without Grade 2 (GS 7 (3+4)),TwoS -118003152,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),315,without Grade 2 (GS 7 (3+4)),TwoS -101003162,101,[T1] Newly diagnosed Pca ,316,without Grade 3 (GS 7 (4+3)),TwoS -102003162,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),316,without Grade 3 (GS 7 (4+3)),TwoS -103003162,103,[T2] PCa treated right away,316,without Grade 3 (GS 7 (4+3)),TwoS -104003162,104,[T2a] PCa treated right away (biopsy or PSA GT 50),316,without Grade 3 (GS 7 (4+3)),TwoS -105003162,105,[T3] PCa under conservative management,316,without Grade 3 (GS 7 (4+3)),TwoS -106003162,106,[T3.1] PCa high/intermediate risk conservative management,316,without Grade 3 (GS 7 (4+3)),TwoS -107003162,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),316,without Grade 3 (GS 7 (4+3)),TwoS -108003162,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,316,without Grade 3 (GS 7 (4+3)),TwoS -109003162,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),316,without Grade 3 (GS 7 (4+3)),TwoS -110003162,110,[T3.3] PCa low risk grade conservative management and intense monitoring,316,without Grade 3 (GS 7 (4+3)),TwoS -111003162,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),316,without Grade 3 (GS 7 (4+3)),TwoS -112003162,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),316,without Grade 3 (GS 7 (4+3)),TwoS -113003162,113,[T4] PCa treated after conservative management ,316,without Grade 3 (GS 7 (4+3)),TwoS -114003162,114,[T4.1] Delayed Curative Management,316,without Grade 3 (GS 7 (4+3)),TwoS -115003162,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),316,without Grade 3 (GS 7 (4+3)),TwoS -116003162,116,[T4.2] Delayed Palliative Management,316,without Grade 3 (GS 7 (4+3)),TwoS -117003162,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),316,without Grade 3 (GS 7 (4+3)),TwoS -118003162,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),316,without Grade 3 (GS 7 (4+3)),TwoS -101003172,101,[T1] Newly diagnosed Pca ,317,without Grade 4 (GS 8),TwoS -102003172,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),317,without Grade 4 (GS 8),TwoS -103003172,103,[T2] PCa treated right away,317,without Grade 4 (GS 8),TwoS -104003172,104,[T2a] PCa treated right away (biopsy or PSA GT 50),317,without Grade 4 (GS 8),TwoS -105003172,105,[T3] PCa under conservative management,317,without Grade 4 (GS 8),TwoS -106003172,106,[T3.1] PCa high/intermediate risk conservative management,317,without Grade 4 (GS 8),TwoS -107003172,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),317,without Grade 4 (GS 8),TwoS -108003172,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,317,without Grade 4 (GS 8),TwoS -109003172,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),317,without Grade 4 (GS 8),TwoS -110003172,110,[T3.3] PCa low risk grade conservative management and intense monitoring,317,without Grade 4 (GS 8),TwoS -111003172,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),317,without Grade 4 (GS 8),TwoS -112003172,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),317,without Grade 4 (GS 8),TwoS -113003172,113,[T4] PCa treated after conservative management ,317,without Grade 4 (GS 8),TwoS -114003172,114,[T4.1] Delayed Curative Management,317,without Grade 4 (GS 8),TwoS -115003172,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),317,without Grade 4 (GS 8),TwoS -116003172,116,[T4.2] Delayed Palliative Management,317,without Grade 4 (GS 8),TwoS -117003172,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),317,without Grade 4 (GS 8),TwoS -118003172,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),317,without Grade 4 (GS 8),TwoS -101003182,101,[T1] Newly diagnosed Pca ,318,without Grade 5 (GS 9-10),TwoS -102003182,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),318,without Grade 5 (GS 9-10),TwoS -103003182,103,[T2] PCa treated right away,318,without Grade 5 (GS 9-10),TwoS -104003182,104,[T2a] PCa treated right away (biopsy or PSA GT 50),318,without Grade 5 (GS 9-10),TwoS -105003182,105,[T3] PCa under conservative management,318,without Grade 5 (GS 9-10),TwoS -106003182,106,[T3.1] PCa high/intermediate risk conservative management,318,without Grade 5 (GS 9-10),TwoS -107003182,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),318,without Grade 5 (GS 9-10),TwoS -108003182,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,318,without Grade 5 (GS 9-10),TwoS -109003182,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),318,without Grade 5 (GS 9-10),TwoS -110003182,110,[T3.3] PCa low risk grade conservative management and intense monitoring,318,without Grade 5 (GS 9-10),TwoS -111003182,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),318,without Grade 5 (GS 9-10),TwoS -112003182,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),318,without Grade 5 (GS 9-10),TwoS -113003182,113,[T4] PCa treated after conservative management ,318,without Grade 5 (GS 9-10),TwoS -114003182,114,[T4.1] Delayed Curative Management,318,without Grade 5 (GS 9-10),TwoS -115003182,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),318,without Grade 5 (GS 9-10),TwoS -116003182,116,[T4.2] Delayed Palliative Management,318,without Grade 5 (GS 9-10),TwoS -117003182,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),318,without Grade 5 (GS 9-10),TwoS -118003182,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),318,without Grade 5 (GS 9-10),TwoS -101003192,101,[T1] Newly diagnosed Pca ,319,without Family History of PCa,TwoS -102003192,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),319,without Family History of PCa,TwoS -103003192,103,[T2] PCa treated right away,319,without Family History of PCa,TwoS -104003192,104,[T2a] PCa treated right away (biopsy or PSA GT 50),319,without Family History of PCa,TwoS -105003192,105,[T3] PCa under conservative management,319,without Family History of PCa,TwoS -106003192,106,[T3.1] PCa high/intermediate risk conservative management,319,without Family History of PCa,TwoS -107003192,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),319,without Family History of PCa,TwoS -108003192,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,319,without Family History of PCa,TwoS -109003192,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),319,without Family History of PCa,TwoS -110003192,110,[T3.3] PCa low risk grade conservative management and intense monitoring,319,without Family History of PCa,TwoS -111003192,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),319,without Family History of PCa,TwoS -112003192,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),319,without Family History of PCa,TwoS -113003192,113,[T4] PCa treated after conservative management ,319,without Family History of PCa,TwoS -114003192,114,[T4.1] Delayed Curative Management,319,without Family History of PCa,TwoS -115003192,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),319,without Family History of PCa,TwoS -116003192,116,[T4.2] Delayed Palliative Management,319,without Family History of PCa,TwoS -117003192,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),319,without Family History of PCa,TwoS -118003192,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),319,without Family History of PCa,TwoS -101003202,101,[T1] Newly diagnosed Pca ,320,without Mutations,TwoS -102003202,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),320,without Mutations,TwoS -103003202,103,[T2] PCa treated right away,320,without Mutations,TwoS -104003202,104,[T2a] PCa treated right away (biopsy or PSA GT 50),320,without Mutations,TwoS -105003202,105,[T3] PCa under conservative management,320,without Mutations,TwoS -106003202,106,[T3.1] PCa high/intermediate risk conservative management,320,without Mutations,TwoS -107003202,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),320,without Mutations,TwoS -108003202,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,320,without Mutations,TwoS -109003202,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),320,without Mutations,TwoS -110003202,110,[T3.3] PCa low risk grade conservative management and intense monitoring,320,without Mutations,TwoS -111003202,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),320,without Mutations,TwoS -112003202,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),320,without Mutations,TwoS -113003202,113,[T4] PCa treated after conservative management ,320,without Mutations,TwoS -114003202,114,[T4.1] Delayed Curative Management,320,without Mutations,TwoS -115003202,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),320,without Mutations,TwoS -116003202,116,[T4.2] Delayed Palliative Management,320,without Mutations,TwoS -117003202,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),320,without Mutations,TwoS -118003202,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),320,without Mutations,TwoS -101003212,101,[T1] Newly diagnosed Pca ,321,without Age below 55,TwoS -102003212,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),321,without Age below 55,TwoS -103003212,103,[T2] PCa treated right away,321,without Age below 55,TwoS -104003212,104,[T2a] PCa treated right away (biopsy or PSA GT 50),321,without Age below 55,TwoS -105003212,105,[T3] PCa under conservative management,321,without Age below 55,TwoS -106003212,106,[T3.1] PCa high/intermediate risk conservative management,321,without Age below 55,TwoS -107003212,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),321,without Age below 55,TwoS -108003212,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,321,without Age below 55,TwoS -109003212,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),321,without Age below 55,TwoS -110003212,110,[T3.3] PCa low risk grade conservative management and intense monitoring,321,without Age below 55,TwoS -111003212,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),321,without Age below 55,TwoS -112003212,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),321,without Age below 55,TwoS -113003212,113,[T4] PCa treated after conservative management ,321,without Age below 55,TwoS -114003212,114,[T4.1] Delayed Curative Management,321,without Age below 55,TwoS -115003212,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),321,without Age below 55,TwoS -116003212,116,[T4.2] Delayed Palliative Management,321,without Age below 55,TwoS -117003212,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),321,without Age below 55,TwoS -118003212,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),321,without Age below 55,TwoS -101003222,101,[T1] Newly diagnosed Pca ,322,without Age 55-80,TwoS -102003222,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),322,without Age 55-80,TwoS -103003222,103,[T2] PCa treated right away,322,without Age 55-80,TwoS -104003222,104,[T2a] PCa treated right away (biopsy or PSA GT 50),322,without Age 55-80,TwoS -105003222,105,[T3] PCa under conservative management,322,without Age 55-80,TwoS -106003222,106,[T3.1] PCa high/intermediate risk conservative management,322,without Age 55-80,TwoS -107003222,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),322,without Age 55-80,TwoS -108003222,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,322,without Age 55-80,TwoS -109003222,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),322,without Age 55-80,TwoS -110003222,110,[T3.3] PCa low risk grade conservative management and intense monitoring,322,without Age 55-80,TwoS -111003222,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),322,without Age 55-80,TwoS -112003222,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),322,without Age 55-80,TwoS -113003222,113,[T4] PCa treated after conservative management ,322,without Age 55-80,TwoS -114003222,114,[T4.1] Delayed Curative Management,322,without Age 55-80,TwoS -115003222,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),322,without Age 55-80,TwoS -116003222,116,[T4.2] Delayed Palliative Management,322,without Age 55-80,TwoS -117003222,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),322,without Age 55-80,TwoS -118003222,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),322,without Age 55-80,TwoS -101003232,101,[T1] Newly diagnosed Pca ,323,without Age above 80,TwoS -102003232,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),323,without Age above 80,TwoS -103003232,103,[T2] PCa treated right away,323,without Age above 80,TwoS -104003232,104,[T2a] PCa treated right away (biopsy or PSA GT 50),323,without Age above 80,TwoS -105003232,105,[T3] PCa under conservative management,323,without Age above 80,TwoS -106003232,106,[T3.1] PCa high/intermediate risk conservative management,323,without Age above 80,TwoS -107003232,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),323,without Age above 80,TwoS -108003232,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,323,without Age above 80,TwoS -109003232,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),323,without Age above 80,TwoS -110003232,110,[T3.3] PCa low risk grade conservative management and intense monitoring,323,without Age above 80,TwoS -111003232,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),323,without Age above 80,TwoS -112003232,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),323,without Age above 80,TwoS -113003232,113,[T4] PCa treated after conservative management ,323,without Age above 80,TwoS -114003232,114,[T4.1] Delayed Curative Management,323,without Age above 80,TwoS -115003232,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),323,without Age above 80,TwoS -116003232,116,[T4.2] Delayed Palliative Management,323,without Age above 80,TwoS -117003232,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),323,without Age above 80,TwoS -118003232,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),323,without Age above 80,TwoS -101003242,101,[T1] Newly diagnosed Pca ,324,without Charlson Comorbidity Index (cut off 0),TwoS -102003242,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),324,without Charlson Comorbidity Index (cut off 0),TwoS -103003242,103,[T2] PCa treated right away,324,without Charlson Comorbidity Index (cut off 0),TwoS -104003242,104,[T2a] PCa treated right away (biopsy or PSA GT 50),324,without Charlson Comorbidity Index (cut off 0),TwoS -105003242,105,[T3] PCa under conservative management,324,without Charlson Comorbidity Index (cut off 0),TwoS -106003242,106,[T3.1] PCa high/intermediate risk conservative management,324,without Charlson Comorbidity Index (cut off 0),TwoS -107003242,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),324,without Charlson Comorbidity Index (cut off 0),TwoS -108003242,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,324,without Charlson Comorbidity Index (cut off 0),TwoS -109003242,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),324,without Charlson Comorbidity Index (cut off 0),TwoS -110003242,110,[T3.3] PCa low risk grade conservative management and intense monitoring,324,without Charlson Comorbidity Index (cut off 0),TwoS -111003242,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),324,without Charlson Comorbidity Index (cut off 0),TwoS -112003242,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),324,without Charlson Comorbidity Index (cut off 0),TwoS -113003242,113,[T4] PCa treated after conservative management ,324,without Charlson Comorbidity Index (cut off 0),TwoS -114003242,114,[T4.1] Delayed Curative Management,324,without Charlson Comorbidity Index (cut off 0),TwoS -115003242,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),324,without Charlson Comorbidity Index (cut off 0),TwoS -116003242,116,[T4.2] Delayed Palliative Management,324,without Charlson Comorbidity Index (cut off 0),TwoS -117003242,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),324,without Charlson Comorbidity Index (cut off 0),TwoS -118003242,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),324,without Charlson Comorbidity Index (cut off 0),TwoS -101003252,101,[T1] Newly diagnosed Pca ,325,without Charlson Comorbidity Index (cut off 1),TwoS -102003252,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),325,without Charlson Comorbidity Index (cut off 1),TwoS -103003252,103,[T2] PCa treated right away,325,without Charlson Comorbidity Index (cut off 1),TwoS -104003252,104,[T2a] PCa treated right away (biopsy or PSA GT 50),325,without Charlson Comorbidity Index (cut off 1),TwoS -105003252,105,[T3] PCa under conservative management,325,without Charlson Comorbidity Index (cut off 1),TwoS -106003252,106,[T3.1] PCa high/intermediate risk conservative management,325,without Charlson Comorbidity Index (cut off 1),TwoS -107003252,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),325,without Charlson Comorbidity Index (cut off 1),TwoS -108003252,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,325,without Charlson Comorbidity Index (cut off 1),TwoS -109003252,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),325,without Charlson Comorbidity Index (cut off 1),TwoS -110003252,110,[T3.3] PCa low risk grade conservative management and intense monitoring,325,without Charlson Comorbidity Index (cut off 1),TwoS -111003252,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),325,without Charlson Comorbidity Index (cut off 1),TwoS -112003252,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),325,without Charlson Comorbidity Index (cut off 1),TwoS -113003252,113,[T4] PCa treated after conservative management ,325,without Charlson Comorbidity Index (cut off 1),TwoS -114003252,114,[T4.1] Delayed Curative Management,325,without Charlson Comorbidity Index (cut off 1),TwoS -115003252,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),325,without Charlson Comorbidity Index (cut off 1),TwoS -116003252,116,[T4.2] Delayed Palliative Management,325,without Charlson Comorbidity Index (cut off 1),TwoS -117003252,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),325,without Charlson Comorbidity Index (cut off 1),TwoS -118003252,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),325,without Charlson Comorbidity Index (cut off 1),TwoS -101003262,101,[T1] Newly diagnosed Pca ,326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -102003262,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -103003262,103,[T2] PCa treated right away,326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -104003262,104,[T2a] PCa treated right away (biopsy or PSA GT 50),326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -105003262,105,[T3] PCa under conservative management,326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -106003262,106,[T3.1] PCa high/intermediate risk conservative management,326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -107003262,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -108003262,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -109003262,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -110003262,110,[T3.3] PCa low risk grade conservative management and intense monitoring,326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -111003262,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -112003262,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -113003262,113,[T4] PCa treated after conservative management ,326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -114003262,114,[T4.1] Delayed Curative Management,326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -115003262,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -116003262,116,[T4.2] Delayed Palliative Management,326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -117003262,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -118003262,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),326,without Charlson Comorbidity Index (cut off greater or equals 2 ),TwoS -101003272,101,[T1] Newly diagnosed Pca ,327,without Other malignancies,TwoS -102003272,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),327,without Other malignancies,TwoS -103003272,103,[T2] PCa treated right away,327,without Other malignancies,TwoS -104003272,104,[T2a] PCa treated right away (biopsy or PSA GT 50),327,without Other malignancies,TwoS -105003272,105,[T3] PCa under conservative management,327,without Other malignancies,TwoS -106003272,106,[T3.1] PCa high/intermediate risk conservative management,327,without Other malignancies,TwoS -107003272,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),327,without Other malignancies,TwoS -108003272,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,327,without Other malignancies,TwoS -109003272,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),327,without Other malignancies,TwoS -110003272,110,[T3.3] PCa low risk grade conservative management and intense monitoring,327,without Other malignancies,TwoS -111003272,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),327,without Other malignancies,TwoS -112003272,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),327,without Other malignancies,TwoS -113003272,113,[T4] PCa treated after conservative management ,327,without Other malignancies,TwoS -114003272,114,[T4.1] Delayed Curative Management,327,without Other malignancies,TwoS -115003272,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),327,without Other malignancies,TwoS -116003272,116,[T4.2] Delayed Palliative Management,327,without Other malignancies,TwoS -117003272,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),327,without Other malignancies,TwoS -118003272,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),327,without Other malignancies,TwoS -101003282,101,[T1] Newly diagnosed Pca ,328,without Total Cardiovascular Disease Event,TwoS -102003282,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),328,without Total Cardiovascular Disease Event,TwoS -103003282,103,[T2] PCa treated right away,328,without Total Cardiovascular Disease Event,TwoS -104003282,104,[T2a] PCa treated right away (biopsy or PSA GT 50),328,without Total Cardiovascular Disease Event,TwoS -105003282,105,[T3] PCa under conservative management,328,without Total Cardiovascular Disease Event,TwoS -106003282,106,[T3.1] PCa high/intermediate risk conservative management,328,without Total Cardiovascular Disease Event,TwoS -107003282,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),328,without Total Cardiovascular Disease Event,TwoS -108003282,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,328,without Total Cardiovascular Disease Event,TwoS -109003282,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),328,without Total Cardiovascular Disease Event,TwoS -110003282,110,[T3.3] PCa low risk grade conservative management and intense monitoring,328,without Total Cardiovascular Disease Event,TwoS -111003282,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),328,without Total Cardiovascular Disease Event,TwoS -112003282,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),328,without Total Cardiovascular Disease Event,TwoS -113003282,113,[T4] PCa treated after conservative management ,328,without Total Cardiovascular Disease Event,TwoS -114003282,114,[T4.1] Delayed Curative Management,328,without Total Cardiovascular Disease Event,TwoS -115003282,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),328,without Total Cardiovascular Disease Event,TwoS -116003282,116,[T4.2] Delayed Palliative Management,328,without Total Cardiovascular Disease Event,TwoS -117003282,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),328,without Total Cardiovascular Disease Event,TwoS -118003282,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),328,without Total Cardiovascular Disease Event,TwoS -101003292,101,[T1] Newly diagnosed Pca ,329,without Stroke,TwoS -102003292,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),329,without Stroke,TwoS -103003292,103,[T2] PCa treated right away,329,without Stroke,TwoS -104003292,104,[T2a] PCa treated right away (biopsy or PSA GT 50),329,without Stroke,TwoS -105003292,105,[T3] PCa under conservative management,329,without Stroke,TwoS -106003292,106,[T3.1] PCa high/intermediate risk conservative management,329,without Stroke,TwoS -107003292,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),329,without Stroke,TwoS -108003292,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,329,without Stroke,TwoS -109003292,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),329,without Stroke,TwoS -110003292,110,[T3.3] PCa low risk grade conservative management and intense monitoring,329,without Stroke,TwoS -111003292,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),329,without Stroke,TwoS -112003292,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),329,without Stroke,TwoS -113003292,113,[T4] PCa treated after conservative management ,329,without Stroke,TwoS -114003292,114,[T4.1] Delayed Curative Management,329,without Stroke,TwoS -115003292,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),329,without Stroke,TwoS -116003292,116,[T4.2] Delayed Palliative Management,329,without Stroke,TwoS -117003292,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),329,without Stroke,TwoS -118003292,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),329,without Stroke,TwoS -101003302,101,[T1] Newly diagnosed Pca ,330,without Type 2 Diabetes,TwoS -102003302,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),330,without Type 2 Diabetes,TwoS -103003302,103,[T2] PCa treated right away,330,without Type 2 Diabetes,TwoS -104003302,104,[T2a] PCa treated right away (biopsy or PSA GT 50),330,without Type 2 Diabetes,TwoS -105003302,105,[T3] PCa under conservative management,330,without Type 2 Diabetes,TwoS -106003302,106,[T3.1] PCa high/intermediate risk conservative management,330,without Type 2 Diabetes,TwoS -107003302,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),330,without Type 2 Diabetes,TwoS -108003302,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,330,without Type 2 Diabetes,TwoS -109003302,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),330,without Type 2 Diabetes,TwoS -110003302,110,[T3.3] PCa low risk grade conservative management and intense monitoring,330,without Type 2 Diabetes,TwoS -111003302,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),330,without Type 2 Diabetes,TwoS -112003302,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),330,without Type 2 Diabetes,TwoS -113003302,113,[T4] PCa treated after conservative management ,330,without Type 2 Diabetes,TwoS -114003302,114,[T4.1] Delayed Curative Management,330,without Type 2 Diabetes,TwoS -115003302,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),330,without Type 2 Diabetes,TwoS -116003302,116,[T4.2] Delayed Palliative Management,330,without Type 2 Diabetes,TwoS -117003302,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),330,without Type 2 Diabetes,TwoS -118003302,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),330,without Type 2 Diabetes,TwoS -101003312,101,[T1] Newly diagnosed Pca ,331,without Hypertension,TwoS -102003312,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),331,without Hypertension,TwoS -103003312,103,[T2] PCa treated right away,331,without Hypertension,TwoS -104003312,104,[T2a] PCa treated right away (biopsy or PSA GT 50),331,without Hypertension,TwoS -105003312,105,[T3] PCa under conservative management,331,without Hypertension,TwoS -106003312,106,[T3.1] PCa high/intermediate risk conservative management,331,without Hypertension,TwoS -107003312,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),331,without Hypertension,TwoS -108003312,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,331,without Hypertension,TwoS -109003312,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),331,without Hypertension,TwoS -110003312,110,[T3.3] PCa low risk grade conservative management and intense monitoring,331,without Hypertension,TwoS -111003312,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),331,without Hypertension,TwoS -112003312,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),331,without Hypertension,TwoS -113003312,113,[T4] PCa treated after conservative management ,331,without Hypertension,TwoS -114003312,114,[T4.1] Delayed Curative Management,331,without Hypertension,TwoS -115003312,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),331,without Hypertension,TwoS -116003312,116,[T4.2] Delayed Palliative Management,331,without Hypertension,TwoS -117003312,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),331,without Hypertension,TwoS -118003312,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),331,without Hypertension,TwoS -101003322,101,[T1] Newly diagnosed Pca ,332,without Obesity,TwoS -102003322,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),332,without Obesity,TwoS -103003322,103,[T2] PCa treated right away,332,without Obesity,TwoS -104003322,104,[T2a] PCa treated right away (biopsy or PSA GT 50),332,without Obesity,TwoS -105003322,105,[T3] PCa under conservative management,332,without Obesity,TwoS -106003322,106,[T3.1] PCa high/intermediate risk conservative management,332,without Obesity,TwoS -107003322,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),332,without Obesity,TwoS -108003322,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,332,without Obesity,TwoS -109003322,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),332,without Obesity,TwoS -110003322,110,[T3.3] PCa low risk grade conservative management and intense monitoring,332,without Obesity,TwoS -111003322,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),332,without Obesity,TwoS -112003322,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),332,without Obesity,TwoS -113003322,113,[T4] PCa treated after conservative management ,332,without Obesity,TwoS -114003322,114,[T4.1] Delayed Curative Management,332,without Obesity,TwoS -115003322,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),332,without Obesity,TwoS -116003322,116,[T4.2] Delayed Palliative Management,332,without Obesity,TwoS -117003322,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),332,without Obesity,TwoS -118003322,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),332,without Obesity,TwoS -101003332,101,[T1] Newly diagnosed Pca ,333,without VTE,TwoS -102003332,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),333,without VTE,TwoS -103003332,103,[T2] PCa treated right away,333,without VTE,TwoS -104003332,104,[T2a] PCa treated right away (biopsy or PSA GT 50),333,without VTE,TwoS -105003332,105,[T3] PCa under conservative management,333,without VTE,TwoS -106003332,106,[T3.1] PCa high/intermediate risk conservative management,333,without VTE,TwoS -107003332,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),333,without VTE,TwoS -108003332,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,333,without VTE,TwoS -109003332,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),333,without VTE,TwoS -110003332,110,[T3.3] PCa low risk grade conservative management and intense monitoring,333,without VTE,TwoS -111003332,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),333,without VTE,TwoS -112003332,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),333,without VTE,TwoS -113003332,113,[T4] PCa treated after conservative management ,333,without VTE,TwoS -114003332,114,[T4.1] Delayed Curative Management,333,without VTE,TwoS -115003332,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),333,without VTE,TwoS -116003332,116,[T4.2] Delayed Palliative Management,333,without VTE,TwoS -117003332,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),333,without VTE,TwoS -118003332,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),333,without VTE,TwoS -101000011,101,[T1] Newly diagnosed Pca ,1,with Full 30-day follow up,TwS -102000011,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),1,with Full 30-day follow up,TwS -103000011,103,[T2] PCa treated right away,1,with Full 30-day follow up,TwS -104000011,104,[T2a] PCa treated right away (biopsy or PSA GT 50),1,with Full 30-day follow up,TwS -105000011,105,[T3] PCa under conservative management,1,with Full 30-day follow up,TwS -106000011,106,[T3.1] PCa high/intermediate risk conservative management,1,with Full 30-day follow up,TwS -107000011,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),1,with Full 30-day follow up,TwS -108000011,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,1,with Full 30-day follow up,TwS -109000011,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),1,with Full 30-day follow up,TwS -110000011,110,[T3.3] PCa low risk grade conservative management and intense monitoring,1,with Full 30-day follow up,TwS -111000011,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),1,with Full 30-day follow up,TwS -112000011,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),1,with Full 30-day follow up,TwS -113000011,113,[T4] PCa treated after conservative management ,1,with Full 30-day follow up,TwS -114000011,114,[T4.1] Delayed Curative Management,1,with Full 30-day follow up,TwS -115000011,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),1,with Full 30-day follow up,TwS -116000011,116,[T4.2] Delayed Palliative Management,1,with Full 30-day follow up,TwS -117000011,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),1,with Full 30-day follow up,TwS -118000011,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),1,with Full 30-day follow up,TwS -101000021,101,[T1] Newly diagnosed Pca ,2,with < 30-day follow up,TwS -102000021,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),2,with < 30-day follow up,TwS -103000021,103,[T2] PCa treated right away,2,with < 30-day follow up,TwS -104000021,104,[T2a] PCa treated right away (biopsy or PSA GT 50),2,with < 30-day follow up,TwS -105000021,105,[T3] PCa under conservative management,2,with < 30-day follow up,TwS -106000021,106,[T3.1] PCa high/intermediate risk conservative management,2,with < 30-day follow up,TwS -107000021,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),2,with < 30-day follow up,TwS -108000021,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,2,with < 30-day follow up,TwS -109000021,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),2,with < 30-day follow up,TwS -110000021,110,[T3.3] PCa low risk grade conservative management and intense monitoring,2,with < 30-day follow up,TwS -111000021,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),2,with < 30-day follow up,TwS -112000021,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),2,with < 30-day follow up,TwS -113000021,113,[T4] PCa treated after conservative management ,2,with < 30-day follow up,TwS -114000021,114,[T4.1] Delayed Curative Management,2,with < 30-day follow up,TwS -115000021,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),2,with < 30-day follow up,TwS -116000021,116,[T4.2] Delayed Palliative Management,2,with < 30-day follow up,TwS -117000021,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),2,with < 30-day follow up,TwS -118000021,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),2,with < 30-day follow up,TwS -101000031,101,[T1] Newly diagnosed Pca ,3,with Sex = Female,TwS -102000031,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),3,with Sex = Female,TwS -103000031,103,[T2] PCa treated right away,3,with Sex = Female,TwS -104000031,104,[T2a] PCa treated right away (biopsy or PSA GT 50),3,with Sex = Female,TwS -105000031,105,[T3] PCa under conservative management,3,with Sex = Female,TwS -106000031,106,[T3.1] PCa high/intermediate risk conservative management,3,with Sex = Female,TwS -107000031,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),3,with Sex = Female,TwS -108000031,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,3,with Sex = Female,TwS -109000031,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),3,with Sex = Female,TwS -110000031,110,[T3.3] PCa low risk grade conservative management and intense monitoring,3,with Sex = Female,TwS -111000031,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),3,with Sex = Female,TwS -112000031,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),3,with Sex = Female,TwS -113000031,113,[T4] PCa treated after conservative management ,3,with Sex = Female,TwS -114000031,114,[T4.1] Delayed Curative Management,3,with Sex = Female,TwS -115000031,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),3,with Sex = Female,TwS -116000031,116,[T4.2] Delayed Palliative Management,3,with Sex = Female,TwS -117000031,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),3,with Sex = Female,TwS -118000031,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),3,with Sex = Female,TwS -101000041,101,[T1] Newly diagnosed Pca ,4,with Sex = Male,TwS -102000041,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),4,with Sex = Male,TwS -103000041,103,[T2] PCa treated right away,4,with Sex = Male,TwS -104000041,104,[T2a] PCa treated right away (biopsy or PSA GT 50),4,with Sex = Male,TwS -105000041,105,[T3] PCa under conservative management,4,with Sex = Male,TwS -106000041,106,[T3.1] PCa high/intermediate risk conservative management,4,with Sex = Male,TwS -107000041,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),4,with Sex = Male,TwS -108000041,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,4,with Sex = Male,TwS -109000041,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),4,with Sex = Male,TwS -110000041,110,[T3.3] PCa low risk grade conservative management and intense monitoring,4,with Sex = Male,TwS -111000041,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),4,with Sex = Male,TwS -112000041,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),4,with Sex = Male,TwS -113000041,113,[T4] PCa treated after conservative management ,4,with Sex = Male,TwS -114000041,114,[T4.1] Delayed Curative Management,4,with Sex = Male,TwS -115000041,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),4,with Sex = Male,TwS -116000041,116,[T4.2] Delayed Palliative Management,4,with Sex = Male,TwS -117000041,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),4,with Sex = Male,TwS -118000041,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),4,with Sex = Male,TwS -101000051,101,[T1] Newly diagnosed Pca ,5,with Age >= 18,TwS -102000051,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),5,with Age >= 18,TwS -103000051,103,[T2] PCa treated right away,5,with Age >= 18,TwS -104000051,104,[T2a] PCa treated right away (biopsy or PSA GT 50),5,with Age >= 18,TwS -105000051,105,[T3] PCa under conservative management,5,with Age >= 18,TwS -106000051,106,[T3.1] PCa high/intermediate risk conservative management,5,with Age >= 18,TwS -107000051,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),5,with Age >= 18,TwS -108000051,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,5,with Age >= 18,TwS -109000051,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),5,with Age >= 18,TwS -110000051,110,[T3.3] PCa low risk grade conservative management and intense monitoring,5,with Age >= 18,TwS -111000051,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),5,with Age >= 18,TwS -112000051,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),5,with Age >= 18,TwS -113000051,113,[T4] PCa treated after conservative management ,5,with Age >= 18,TwS -114000051,114,[T4.1] Delayed Curative Management,5,with Age >= 18,TwS -115000051,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),5,with Age >= 18,TwS -116000051,116,[T4.2] Delayed Palliative Management,5,with Age >= 18,TwS -117000051,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),5,with Age >= 18,TwS -118000051,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),5,with Age >= 18,TwS -101000061,101,[T1] Newly diagnosed Pca ,6,with Age < 18,TwS -102000061,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),6,with Age < 18,TwS -103000061,103,[T2] PCa treated right away,6,with Age < 18,TwS -104000061,104,[T2a] PCa treated right away (biopsy or PSA GT 50),6,with Age < 18,TwS -105000061,105,[T3] PCa under conservative management,6,with Age < 18,TwS -106000061,106,[T3.1] PCa high/intermediate risk conservative management,6,with Age < 18,TwS -107000061,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),6,with Age < 18,TwS -108000061,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,6,with Age < 18,TwS -109000061,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),6,with Age < 18,TwS -110000061,110,[T3.3] PCa low risk grade conservative management and intense monitoring,6,with Age < 18,TwS -111000061,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),6,with Age < 18,TwS -112000061,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),6,with Age < 18,TwS -113000061,113,[T4] PCa treated after conservative management ,6,with Age < 18,TwS -114000061,114,[T4.1] Delayed Curative Management,6,with Age < 18,TwS -115000061,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),6,with Age < 18,TwS -116000061,116,[T4.2] Delayed Palliative Management,6,with Age < 18,TwS -117000061,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),6,with Age < 18,TwS -118000061,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),6,with Age < 18,TwS -101000071,101,[T1] Newly diagnosed Pca ,7,with Age >= 65,TwS -102000071,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),7,with Age >= 65,TwS -103000071,103,[T2] PCa treated right away,7,with Age >= 65,TwS -104000071,104,[T2a] PCa treated right away (biopsy or PSA GT 50),7,with Age >= 65,TwS -105000071,105,[T3] PCa under conservative management,7,with Age >= 65,TwS -106000071,106,[T3.1] PCa high/intermediate risk conservative management,7,with Age >= 65,TwS -107000071,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),7,with Age >= 65,TwS -108000071,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,7,with Age >= 65,TwS -109000071,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),7,with Age >= 65,TwS -110000071,110,[T3.3] PCa low risk grade conservative management and intense monitoring,7,with Age >= 65,TwS -111000071,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),7,with Age >= 65,TwS -112000071,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),7,with Age >= 65,TwS -113000071,113,[T4] PCa treated after conservative management ,7,with Age >= 65,TwS -114000071,114,[T4.1] Delayed Curative Management,7,with Age >= 65,TwS -115000071,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),7,with Age >= 65,TwS -116000071,116,[T4.2] Delayed Palliative Management,7,with Age >= 65,TwS -117000071,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),7,with Age >= 65,TwS -118000071,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),7,with Age >= 65,TwS -101000081,101,[T1] Newly diagnosed Pca ,8,with Age < 65,TwS -102000081,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),8,with Age < 65,TwS -103000081,103,[T2] PCa treated right away,8,with Age < 65,TwS -104000081,104,[T2a] PCa treated right away (biopsy or PSA GT 50),8,with Age < 65,TwS -105000081,105,[T3] PCa under conservative management,8,with Age < 65,TwS -106000081,106,[T3.1] PCa high/intermediate risk conservative management,8,with Age < 65,TwS -107000081,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),8,with Age < 65,TwS -108000081,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,8,with Age < 65,TwS -109000081,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),8,with Age < 65,TwS -110000081,110,[T3.3] PCa low risk grade conservative management and intense monitoring,8,with Age < 65,TwS -111000081,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),8,with Age < 65,TwS -112000081,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),8,with Age < 65,TwS -113000081,113,[T4] PCa treated after conservative management ,8,with Age < 65,TwS -114000081,114,[T4.1] Delayed Curative Management,8,with Age < 65,TwS -115000081,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),8,with Age < 65,TwS -116000081,116,[T4.2] Delayed Palliative Management,8,with Age < 65,TwS -117000081,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),8,with Age < 65,TwS -118000081,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),8,with Age < 65,TwS -101000091,101,[T1] Newly diagnosed Pca ,9,with Black or African American,TwS -102000091,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),9,with Black or African American,TwS -103000091,103,[T2] PCa treated right away,9,with Black or African American,TwS -104000091,104,[T2a] PCa treated right away (biopsy or PSA GT 50),9,with Black or African American,TwS -105000091,105,[T3] PCa under conservative management,9,with Black or African American,TwS -106000091,106,[T3.1] PCa high/intermediate risk conservative management,9,with Black or African American,TwS -107000091,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),9,with Black or African American,TwS -108000091,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,9,with Black or African American,TwS -109000091,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),9,with Black or African American,TwS -110000091,110,[T3.3] PCa low risk grade conservative management and intense monitoring,9,with Black or African American,TwS -111000091,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),9,with Black or African American,TwS -112000091,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),9,with Black or African American,TwS -113000091,113,[T4] PCa treated after conservative management ,9,with Black or African American,TwS -114000091,114,[T4.1] Delayed Curative Management,9,with Black or African American,TwS -115000091,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),9,with Black or African American,TwS -116000091,116,[T4.2] Delayed Palliative Management,9,with Black or African American,TwS -117000091,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),9,with Black or African American,TwS -118000091,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),9,with Black or African American,TwS -101000101,101,[T1] Newly diagnosed Pca ,10,with White,TwS -102000101,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),10,with White,TwS -103000101,103,[T2] PCa treated right away,10,with White,TwS -104000101,104,[T2a] PCa treated right away (biopsy or PSA GT 50),10,with White,TwS -105000101,105,[T3] PCa under conservative management,10,with White,TwS -106000101,106,[T3.1] PCa high/intermediate risk conservative management,10,with White,TwS -107000101,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),10,with White,TwS -108000101,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,10,with White,TwS -109000101,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),10,with White,TwS -110000101,110,[T3.3] PCa low risk grade conservative management and intense monitoring,10,with White,TwS -111000101,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),10,with White,TwS -112000101,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),10,with White,TwS -113000101,113,[T4] PCa treated after conservative management ,10,with White,TwS -114000101,114,[T4.1] Delayed Curative Management,10,with White,TwS -115000101,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),10,with White,TwS -116000101,116,[T4.2] Delayed Palliative Management,10,with White,TwS -117000101,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),10,with White,TwS -118000101,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),10,with White,TwS -101003011,101,[T1] Newly diagnosed Pca ,301,with High-Risk,TwS -102003011,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),301,with High-Risk,TwS -103003011,103,[T2] PCa treated right away,301,with High-Risk,TwS -104003011,104,[T2a] PCa treated right away (biopsy or PSA GT 50),301,with High-Risk,TwS -105003011,105,[T3] PCa under conservative management,301,with High-Risk,TwS -106003011,106,[T3.1] PCa high/intermediate risk conservative management,301,with High-Risk,TwS -107003011,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),301,with High-Risk,TwS -108003011,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,301,with High-Risk,TwS -109003011,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),301,with High-Risk,TwS -110003011,110,[T3.3] PCa low risk grade conservative management and intense monitoring,301,with High-Risk,TwS -111003011,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),301,with High-Risk,TwS -112003011,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),301,with High-Risk,TwS -113003011,113,[T4] PCa treated after conservative management ,301,with High-Risk,TwS -114003011,114,[T4.1] Delayed Curative Management,301,with High-Risk,TwS -115003011,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),301,with High-Risk,TwS -116003011,116,[T4.2] Delayed Palliative Management,301,with High-Risk,TwS -117003011,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),301,with High-Risk,TwS -118003011,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),301,with High-Risk,TwS -101003021,101,[T1] Newly diagnosed Pca ,302,with Low-Risk,TwS -102003021,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),302,with Low-Risk,TwS -103003021,103,[T2] PCa treated right away,302,with Low-Risk,TwS -104003021,104,[T2a] PCa treated right away (biopsy or PSA GT 50),302,with Low-Risk,TwS -105003021,105,[T3] PCa under conservative management,302,with Low-Risk,TwS -106003021,106,[T3.1] PCa high/intermediate risk conservative management,302,with Low-Risk,TwS -107003021,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),302,with Low-Risk,TwS -108003021,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,302,with Low-Risk,TwS -109003021,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),302,with Low-Risk,TwS -110003021,110,[T3.3] PCa low risk grade conservative management and intense monitoring,302,with Low-Risk,TwS -111003021,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),302,with Low-Risk,TwS -112003021,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),302,with Low-Risk,TwS -113003021,113,[T4] PCa treated after conservative management ,302,with Low-Risk,TwS -114003021,114,[T4.1] Delayed Curative Management,302,with Low-Risk,TwS -115003021,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),302,with Low-Risk,TwS -116003021,116,[T4.2] Delayed Palliative Management,302,with Low-Risk,TwS -117003021,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),302,with Low-Risk,TwS -118003021,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),302,with Low-Risk,TwS -101003031,101,[T1] Newly diagnosed Pca ,303,with Intermediate-Risk,TwS -102003031,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),303,with Intermediate-Risk,TwS -103003031,103,[T2] PCa treated right away,303,with Intermediate-Risk,TwS -104003031,104,[T2a] PCa treated right away (biopsy or PSA GT 50),303,with Intermediate-Risk,TwS -105003031,105,[T3] PCa under conservative management,303,with Intermediate-Risk,TwS -106003031,106,[T3.1] PCa high/intermediate risk conservative management,303,with Intermediate-Risk,TwS -107003031,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),303,with Intermediate-Risk,TwS -108003031,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,303,with Intermediate-Risk,TwS -109003031,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),303,with Intermediate-Risk,TwS -110003031,110,[T3.3] PCa low risk grade conservative management and intense monitoring,303,with Intermediate-Risk,TwS -111003031,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),303,with Intermediate-Risk,TwS -112003031,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),303,with Intermediate-Risk,TwS -113003031,113,[T4] PCa treated after conservative management ,303,with Intermediate-Risk,TwS -114003031,114,[T4.1] Delayed Curative Management,303,with Intermediate-Risk,TwS -115003031,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),303,with Intermediate-Risk,TwS -116003031,116,[T4.2] Delayed Palliative Management,303,with Intermediate-Risk,TwS -117003031,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),303,with Intermediate-Risk,TwS -118003031,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),303,with Intermediate-Risk,TwS -101003041,101,[T1] Newly diagnosed Pca ,304,with Metastatic Dx Extent,TwS -102003041,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),304,with Metastatic Dx Extent,TwS -103003041,103,[T2] PCa treated right away,304,with Metastatic Dx Extent,TwS -104003041,104,[T2a] PCa treated right away (biopsy or PSA GT 50),304,with Metastatic Dx Extent,TwS -105003041,105,[T3] PCa under conservative management,304,with Metastatic Dx Extent,TwS -106003041,106,[T3.1] PCa high/intermediate risk conservative management,304,with Metastatic Dx Extent,TwS -107003041,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),304,with Metastatic Dx Extent,TwS -108003041,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,304,with Metastatic Dx Extent,TwS -109003041,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),304,with Metastatic Dx Extent,TwS -110003041,110,[T3.3] PCa low risk grade conservative management and intense monitoring,304,with Metastatic Dx Extent,TwS -111003041,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),304,with Metastatic Dx Extent,TwS -112003041,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),304,with Metastatic Dx Extent,TwS -113003041,113,[T4] PCa treated after conservative management ,304,with Metastatic Dx Extent,TwS -114003041,114,[T4.1] Delayed Curative Management,304,with Metastatic Dx Extent,TwS -115003041,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),304,with Metastatic Dx Extent,TwS -116003041,116,[T4.2] Delayed Palliative Management,304,with Metastatic Dx Extent,TwS -117003041,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),304,with Metastatic Dx Extent,TwS -118003041,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),304,with Metastatic Dx Extent,TwS -101003051,101,[T1] Newly diagnosed Pca ,305,with Locally advanced Dx Extent,TwS -102003051,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),305,with Locally advanced Dx Extent,TwS -103003051,103,[T2] PCa treated right away,305,with Locally advanced Dx Extent,TwS -104003051,104,[T2a] PCa treated right away (biopsy or PSA GT 50),305,with Locally advanced Dx Extent,TwS -105003051,105,[T3] PCa under conservative management,305,with Locally advanced Dx Extent,TwS -106003051,106,[T3.1] PCa high/intermediate risk conservative management,305,with Locally advanced Dx Extent,TwS -107003051,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),305,with Locally advanced Dx Extent,TwS -108003051,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,305,with Locally advanced Dx Extent,TwS -109003051,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),305,with Locally advanced Dx Extent,TwS -110003051,110,[T3.3] PCa low risk grade conservative management and intense monitoring,305,with Locally advanced Dx Extent,TwS -111003051,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),305,with Locally advanced Dx Extent,TwS -112003051,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),305,with Locally advanced Dx Extent,TwS -113003051,113,[T4] PCa treated after conservative management ,305,with Locally advanced Dx Extent,TwS -114003051,114,[T4.1] Delayed Curative Management,305,with Locally advanced Dx Extent,TwS -115003051,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),305,with Locally advanced Dx Extent,TwS -116003051,116,[T4.2] Delayed Palliative Management,305,with Locally advanced Dx Extent,TwS -117003051,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),305,with Locally advanced Dx Extent,TwS -118003051,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),305,with Locally advanced Dx Extent,TwS -101003061,101,[T1] Newly diagnosed Pca ,306,with Localized Dx Extent,TwS -102003061,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),306,with Localized Dx Extent,TwS -103003061,103,[T2] PCa treated right away,306,with Localized Dx Extent,TwS -104003061,104,[T2a] PCa treated right away (biopsy or PSA GT 50),306,with Localized Dx Extent,TwS -105003061,105,[T3] PCa under conservative management,306,with Localized Dx Extent,TwS -106003061,106,[T3.1] PCa high/intermediate risk conservative management,306,with Localized Dx Extent,TwS -107003061,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),306,with Localized Dx Extent,TwS -108003061,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,306,with Localized Dx Extent,TwS -109003061,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),306,with Localized Dx Extent,TwS -110003061,110,[T3.3] PCa low risk grade conservative management and intense monitoring,306,with Localized Dx Extent,TwS -111003061,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),306,with Localized Dx Extent,TwS -112003061,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),306,with Localized Dx Extent,TwS -113003061,113,[T4] PCa treated after conservative management ,306,with Localized Dx Extent,TwS -114003061,114,[T4.1] Delayed Curative Management,306,with Localized Dx Extent,TwS -115003061,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),306,with Localized Dx Extent,TwS -116003061,116,[T4.2] Delayed Palliative Management,306,with Localized Dx Extent,TwS -117003061,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),306,with Localized Dx Extent,TwS -118003061,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),306,with Localized Dx Extent,TwS -101003071,101,[T1] Newly diagnosed Pca ,307,with PSA greater than 20,TwS -102003071,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),307,with PSA greater than 20,TwS -103003071,103,[T2] PCa treated right away,307,with PSA greater than 20,TwS -104003071,104,[T2a] PCa treated right away (biopsy or PSA GT 50),307,with PSA greater than 20,TwS -105003071,105,[T3] PCa under conservative management,307,with PSA greater than 20,TwS -106003071,106,[T3.1] PCa high/intermediate risk conservative management,307,with PSA greater than 20,TwS -107003071,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),307,with PSA greater than 20,TwS -108003071,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,307,with PSA greater than 20,TwS -109003071,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),307,with PSA greater than 20,TwS -110003071,110,[T3.3] PCa low risk grade conservative management and intense monitoring,307,with PSA greater than 20,TwS -111003071,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),307,with PSA greater than 20,TwS -112003071,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),307,with PSA greater than 20,TwS -113003071,113,[T4] PCa treated after conservative management ,307,with PSA greater than 20,TwS -114003071,114,[T4.1] Delayed Curative Management,307,with PSA greater than 20,TwS -115003071,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),307,with PSA greater than 20,TwS -116003071,116,[T4.2] Delayed Palliative Management,307,with PSA greater than 20,TwS -117003071,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),307,with PSA greater than 20,TwS -118003071,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),307,with PSA greater than 20,TwS -101003081,101,[T1] Newly diagnosed Pca ,308,with PSA less than 10,TwS -102003081,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),308,with PSA less than 10,TwS -103003081,103,[T2] PCa treated right away,308,with PSA less than 10,TwS -104003081,104,[T2a] PCa treated right away (biopsy or PSA GT 50),308,with PSA less than 10,TwS -105003081,105,[T3] PCa under conservative management,308,with PSA less than 10,TwS -106003081,106,[T3.1] PCa high/intermediate risk conservative management,308,with PSA less than 10,TwS -107003081,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),308,with PSA less than 10,TwS -108003081,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,308,with PSA less than 10,TwS -109003081,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),308,with PSA less than 10,TwS -110003081,110,[T3.3] PCa low risk grade conservative management and intense monitoring,308,with PSA less than 10,TwS -111003081,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),308,with PSA less than 10,TwS -112003081,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),308,with PSA less than 10,TwS -113003081,113,[T4] PCa treated after conservative management ,308,with PSA less than 10,TwS -114003081,114,[T4.1] Delayed Curative Management,308,with PSA less than 10,TwS -115003081,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),308,with PSA less than 10,TwS -116003081,116,[T4.2] Delayed Palliative Management,308,with PSA less than 10,TwS -117003081,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),308,with PSA less than 10,TwS -118003081,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),308,with PSA less than 10,TwS -101003091,101,[T1] Newly diagnosed Pca ,309,with PSA 10-20,TwS -102003091,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),309,with PSA 10-20,TwS -103003091,103,[T2] PCa treated right away,309,with PSA 10-20,TwS -104003091,104,[T2a] PCa treated right away (biopsy or PSA GT 50),309,with PSA 10-20,TwS -105003091,105,[T3] PCa under conservative management,309,with PSA 10-20,TwS -106003091,106,[T3.1] PCa high/intermediate risk conservative management,309,with PSA 10-20,TwS -107003091,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),309,with PSA 10-20,TwS -108003091,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,309,with PSA 10-20,TwS -109003091,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),309,with PSA 10-20,TwS -110003091,110,[T3.3] PCa low risk grade conservative management and intense monitoring,309,with PSA 10-20,TwS -111003091,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),309,with PSA 10-20,TwS -112003091,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),309,with PSA 10-20,TwS -113003091,113,[T4] PCa treated after conservative management ,309,with PSA 10-20,TwS -114003091,114,[T4.1] Delayed Curative Management,309,with PSA 10-20,TwS -115003091,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),309,with PSA 10-20,TwS -116003091,116,[T4.2] Delayed Palliative Management,309,with PSA 10-20,TwS -117003091,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),309,with PSA 10-20,TwS -118003091,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),309,with PSA 10-20,TwS -101003101,101,[T1] Newly diagnosed Pca ,310,with Stage T1,TwS -102003101,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),310,with Stage T1,TwS -103003101,103,[T2] PCa treated right away,310,with Stage T1,TwS -104003101,104,[T2a] PCa treated right away (biopsy or PSA GT 50),310,with Stage T1,TwS -105003101,105,[T3] PCa under conservative management,310,with Stage T1,TwS -106003101,106,[T3.1] PCa high/intermediate risk conservative management,310,with Stage T1,TwS -107003101,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),310,with Stage T1,TwS -108003101,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,310,with Stage T1,TwS -109003101,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),310,with Stage T1,TwS -110003101,110,[T3.3] PCa low risk grade conservative management and intense monitoring,310,with Stage T1,TwS -111003101,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),310,with Stage T1,TwS -112003101,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),310,with Stage T1,TwS -113003101,113,[T4] PCa treated after conservative management ,310,with Stage T1,TwS -114003101,114,[T4.1] Delayed Curative Management,310,with Stage T1,TwS -115003101,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),310,with Stage T1,TwS -116003101,116,[T4.2] Delayed Palliative Management,310,with Stage T1,TwS -117003101,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),310,with Stage T1,TwS -118003101,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),310,with Stage T1,TwS -101003111,101,[T1] Newly diagnosed Pca ,311,with Stage T2,TwS -102003111,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),311,with Stage T2,TwS -103003111,103,[T2] PCa treated right away,311,with Stage T2,TwS -104003111,104,[T2a] PCa treated right away (biopsy or PSA GT 50),311,with Stage T2,TwS -105003111,105,[T3] PCa under conservative management,311,with Stage T2,TwS -106003111,106,[T3.1] PCa high/intermediate risk conservative management,311,with Stage T2,TwS -107003111,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),311,with Stage T2,TwS -108003111,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,311,with Stage T2,TwS -109003111,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),311,with Stage T2,TwS -110003111,110,[T3.3] PCa low risk grade conservative management and intense monitoring,311,with Stage T2,TwS -111003111,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),311,with Stage T2,TwS -112003111,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),311,with Stage T2,TwS -113003111,113,[T4] PCa treated after conservative management ,311,with Stage T2,TwS -114003111,114,[T4.1] Delayed Curative Management,311,with Stage T2,TwS -115003111,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),311,with Stage T2,TwS -116003111,116,[T4.2] Delayed Palliative Management,311,with Stage T2,TwS -117003111,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),311,with Stage T2,TwS -118003111,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),311,with Stage T2,TwS -101003121,101,[T1] Newly diagnosed Pca ,312,with Stage T3 or T4,TwS -102003121,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),312,with Stage T3 or T4,TwS -103003121,103,[T2] PCa treated right away,312,with Stage T3 or T4,TwS -104003121,104,[T2a] PCa treated right away (biopsy or PSA GT 50),312,with Stage T3 or T4,TwS -105003121,105,[T3] PCa under conservative management,312,with Stage T3 or T4,TwS -106003121,106,[T3.1] PCa high/intermediate risk conservative management,312,with Stage T3 or T4,TwS -107003121,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),312,with Stage T3 or T4,TwS -108003121,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,312,with Stage T3 or T4,TwS -109003121,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),312,with Stage T3 or T4,TwS -110003121,110,[T3.3] PCa low risk grade conservative management and intense monitoring,312,with Stage T3 or T4,TwS -111003121,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),312,with Stage T3 or T4,TwS -112003121,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),312,with Stage T3 or T4,TwS -113003121,113,[T4] PCa treated after conservative management ,312,with Stage T3 or T4,TwS -114003121,114,[T4.1] Delayed Curative Management,312,with Stage T3 or T4,TwS -115003121,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),312,with Stage T3 or T4,TwS -116003121,116,[T4.2] Delayed Palliative Management,312,with Stage T3 or T4,TwS -117003121,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),312,with Stage T3 or T4,TwS -118003121,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),312,with Stage T3 or T4,TwS -101003131,101,[T1] Newly diagnosed Pca ,313,with Physical Therapy,TwS -102003131,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),313,with Physical Therapy,TwS -103003131,103,[T2] PCa treated right away,313,with Physical Therapy,TwS -104003131,104,[T2a] PCa treated right away (biopsy or PSA GT 50),313,with Physical Therapy,TwS -105003131,105,[T3] PCa under conservative management,313,with Physical Therapy,TwS -106003131,106,[T3.1] PCa high/intermediate risk conservative management,313,with Physical Therapy,TwS -107003131,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),313,with Physical Therapy,TwS -108003131,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,313,with Physical Therapy,TwS -109003131,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),313,with Physical Therapy,TwS -110003131,110,[T3.3] PCa low risk grade conservative management and intense monitoring,313,with Physical Therapy,TwS -111003131,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),313,with Physical Therapy,TwS -112003131,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),313,with Physical Therapy,TwS -113003131,113,[T4] PCa treated after conservative management ,313,with Physical Therapy,TwS -114003131,114,[T4.1] Delayed Curative Management,313,with Physical Therapy,TwS -115003131,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),313,with Physical Therapy,TwS -116003131,116,[T4.2] Delayed Palliative Management,313,with Physical Therapy,TwS -117003131,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),313,with Physical Therapy,TwS -118003131,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),313,with Physical Therapy,TwS -101003141,101,[T1] Newly diagnosed Pca ,314,with Grade 1 (GS 2-6),TwS -102003141,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),314,with Grade 1 (GS 2-6),TwS -103003141,103,[T2] PCa treated right away,314,with Grade 1 (GS 2-6),TwS -104003141,104,[T2a] PCa treated right away (biopsy or PSA GT 50),314,with Grade 1 (GS 2-6),TwS -105003141,105,[T3] PCa under conservative management,314,with Grade 1 (GS 2-6),TwS -106003141,106,[T3.1] PCa high/intermediate risk conservative management,314,with Grade 1 (GS 2-6),TwS -107003141,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),314,with Grade 1 (GS 2-6),TwS -108003141,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,314,with Grade 1 (GS 2-6),TwS -109003141,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),314,with Grade 1 (GS 2-6),TwS -110003141,110,[T3.3] PCa low risk grade conservative management and intense monitoring,314,with Grade 1 (GS 2-6),TwS -111003141,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),314,with Grade 1 (GS 2-6),TwS -112003141,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),314,with Grade 1 (GS 2-6),TwS -113003141,113,[T4] PCa treated after conservative management ,314,with Grade 1 (GS 2-6),TwS -114003141,114,[T4.1] Delayed Curative Management,314,with Grade 1 (GS 2-6),TwS -115003141,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),314,with Grade 1 (GS 2-6),TwS -116003141,116,[T4.2] Delayed Palliative Management,314,with Grade 1 (GS 2-6),TwS -117003141,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),314,with Grade 1 (GS 2-6),TwS -118003141,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),314,with Grade 1 (GS 2-6),TwS -101003151,101,[T1] Newly diagnosed Pca ,315,with Grade 2 (GS 7 (3+4)),TwS -102003151,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),315,with Grade 2 (GS 7 (3+4)),TwS -103003151,103,[T2] PCa treated right away,315,with Grade 2 (GS 7 (3+4)),TwS -104003151,104,[T2a] PCa treated right away (biopsy or PSA GT 50),315,with Grade 2 (GS 7 (3+4)),TwS -105003151,105,[T3] PCa under conservative management,315,with Grade 2 (GS 7 (3+4)),TwS -106003151,106,[T3.1] PCa high/intermediate risk conservative management,315,with Grade 2 (GS 7 (3+4)),TwS -107003151,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),315,with Grade 2 (GS 7 (3+4)),TwS -108003151,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,315,with Grade 2 (GS 7 (3+4)),TwS -109003151,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),315,with Grade 2 (GS 7 (3+4)),TwS -110003151,110,[T3.3] PCa low risk grade conservative management and intense monitoring,315,with Grade 2 (GS 7 (3+4)),TwS -111003151,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),315,with Grade 2 (GS 7 (3+4)),TwS -112003151,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),315,with Grade 2 (GS 7 (3+4)),TwS -113003151,113,[T4] PCa treated after conservative management ,315,with Grade 2 (GS 7 (3+4)),TwS -114003151,114,[T4.1] Delayed Curative Management,315,with Grade 2 (GS 7 (3+4)),TwS -115003151,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),315,with Grade 2 (GS 7 (3+4)),TwS -116003151,116,[T4.2] Delayed Palliative Management,315,with Grade 2 (GS 7 (3+4)),TwS -117003151,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),315,with Grade 2 (GS 7 (3+4)),TwS -118003151,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),315,with Grade 2 (GS 7 (3+4)),TwS -101003161,101,[T1] Newly diagnosed Pca ,316,with Grade 3 (GS 7 (4+3)),TwS -102003161,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),316,with Grade 3 (GS 7 (4+3)),TwS -103003161,103,[T2] PCa treated right away,316,with Grade 3 (GS 7 (4+3)),TwS -104003161,104,[T2a] PCa treated right away (biopsy or PSA GT 50),316,with Grade 3 (GS 7 (4+3)),TwS -105003161,105,[T3] PCa under conservative management,316,with Grade 3 (GS 7 (4+3)),TwS -106003161,106,[T3.1] PCa high/intermediate risk conservative management,316,with Grade 3 (GS 7 (4+3)),TwS -107003161,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),316,with Grade 3 (GS 7 (4+3)),TwS -108003161,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,316,with Grade 3 (GS 7 (4+3)),TwS -109003161,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),316,with Grade 3 (GS 7 (4+3)),TwS -110003161,110,[T3.3] PCa low risk grade conservative management and intense monitoring,316,with Grade 3 (GS 7 (4+3)),TwS -111003161,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),316,with Grade 3 (GS 7 (4+3)),TwS -112003161,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),316,with Grade 3 (GS 7 (4+3)),TwS -113003161,113,[T4] PCa treated after conservative management ,316,with Grade 3 (GS 7 (4+3)),TwS -114003161,114,[T4.1] Delayed Curative Management,316,with Grade 3 (GS 7 (4+3)),TwS -115003161,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),316,with Grade 3 (GS 7 (4+3)),TwS -116003161,116,[T4.2] Delayed Palliative Management,316,with Grade 3 (GS 7 (4+3)),TwS -117003161,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),316,with Grade 3 (GS 7 (4+3)),TwS -118003161,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),316,with Grade 3 (GS 7 (4+3)),TwS -101003171,101,[T1] Newly diagnosed Pca ,317,with Grade 4 (GS 8),TwS -102003171,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),317,with Grade 4 (GS 8),TwS -103003171,103,[T2] PCa treated right away,317,with Grade 4 (GS 8),TwS -104003171,104,[T2a] PCa treated right away (biopsy or PSA GT 50),317,with Grade 4 (GS 8),TwS -105003171,105,[T3] PCa under conservative management,317,with Grade 4 (GS 8),TwS -106003171,106,[T3.1] PCa high/intermediate risk conservative management,317,with Grade 4 (GS 8),TwS -107003171,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),317,with Grade 4 (GS 8),TwS -108003171,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,317,with Grade 4 (GS 8),TwS -109003171,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),317,with Grade 4 (GS 8),TwS -110003171,110,[T3.3] PCa low risk grade conservative management and intense monitoring,317,with Grade 4 (GS 8),TwS -111003171,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),317,with Grade 4 (GS 8),TwS -112003171,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),317,with Grade 4 (GS 8),TwS -113003171,113,[T4] PCa treated after conservative management ,317,with Grade 4 (GS 8),TwS -114003171,114,[T4.1] Delayed Curative Management,317,with Grade 4 (GS 8),TwS -115003171,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),317,with Grade 4 (GS 8),TwS -116003171,116,[T4.2] Delayed Palliative Management,317,with Grade 4 (GS 8),TwS -117003171,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),317,with Grade 4 (GS 8),TwS -118003171,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),317,with Grade 4 (GS 8),TwS -101003181,101,[T1] Newly diagnosed Pca ,318,with Grade 5 (GS 9-10),TwS -102003181,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),318,with Grade 5 (GS 9-10),TwS -103003181,103,[T2] PCa treated right away,318,with Grade 5 (GS 9-10),TwS -104003181,104,[T2a] PCa treated right away (biopsy or PSA GT 50),318,with Grade 5 (GS 9-10),TwS -105003181,105,[T3] PCa under conservative management,318,with Grade 5 (GS 9-10),TwS -106003181,106,[T3.1] PCa high/intermediate risk conservative management,318,with Grade 5 (GS 9-10),TwS -107003181,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),318,with Grade 5 (GS 9-10),TwS -108003181,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,318,with Grade 5 (GS 9-10),TwS -109003181,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),318,with Grade 5 (GS 9-10),TwS -110003181,110,[T3.3] PCa low risk grade conservative management and intense monitoring,318,with Grade 5 (GS 9-10),TwS -111003181,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),318,with Grade 5 (GS 9-10),TwS -112003181,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),318,with Grade 5 (GS 9-10),TwS -113003181,113,[T4] PCa treated after conservative management ,318,with Grade 5 (GS 9-10),TwS -114003181,114,[T4.1] Delayed Curative Management,318,with Grade 5 (GS 9-10),TwS -115003181,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),318,with Grade 5 (GS 9-10),TwS -116003181,116,[T4.2] Delayed Palliative Management,318,with Grade 5 (GS 9-10),TwS -117003181,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),318,with Grade 5 (GS 9-10),TwS -118003181,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),318,with Grade 5 (GS 9-10),TwS -101003191,101,[T1] Newly diagnosed Pca ,319,with Family History of PCa,TwS -102003191,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),319,with Family History of PCa,TwS -103003191,103,[T2] PCa treated right away,319,with Family History of PCa,TwS -104003191,104,[T2a] PCa treated right away (biopsy or PSA GT 50),319,with Family History of PCa,TwS -105003191,105,[T3] PCa under conservative management,319,with Family History of PCa,TwS -106003191,106,[T3.1] PCa high/intermediate risk conservative management,319,with Family History of PCa,TwS -107003191,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),319,with Family History of PCa,TwS -108003191,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,319,with Family History of PCa,TwS -109003191,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),319,with Family History of PCa,TwS -110003191,110,[T3.3] PCa low risk grade conservative management and intense monitoring,319,with Family History of PCa,TwS -111003191,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),319,with Family History of PCa,TwS -112003191,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),319,with Family History of PCa,TwS -113003191,113,[T4] PCa treated after conservative management ,319,with Family History of PCa,TwS -114003191,114,[T4.1] Delayed Curative Management,319,with Family History of PCa,TwS -115003191,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),319,with Family History of PCa,TwS -116003191,116,[T4.2] Delayed Palliative Management,319,with Family History of PCa,TwS -117003191,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),319,with Family History of PCa,TwS -118003191,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),319,with Family History of PCa,TwS -101003201,101,[T1] Newly diagnosed Pca ,320,with Mutations,TwS -102003201,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),320,with Mutations,TwS -103003201,103,[T2] PCa treated right away,320,with Mutations,TwS -104003201,104,[T2a] PCa treated right away (biopsy or PSA GT 50),320,with Mutations,TwS -105003201,105,[T3] PCa under conservative management,320,with Mutations,TwS -106003201,106,[T3.1] PCa high/intermediate risk conservative management,320,with Mutations,TwS -107003201,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),320,with Mutations,TwS -108003201,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,320,with Mutations,TwS -109003201,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),320,with Mutations,TwS -110003201,110,[T3.3] PCa low risk grade conservative management and intense monitoring,320,with Mutations,TwS -111003201,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),320,with Mutations,TwS -112003201,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),320,with Mutations,TwS -113003201,113,[T4] PCa treated after conservative management ,320,with Mutations,TwS -114003201,114,[T4.1] Delayed Curative Management,320,with Mutations,TwS -115003201,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),320,with Mutations,TwS -116003201,116,[T4.2] Delayed Palliative Management,320,with Mutations,TwS -117003201,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),320,with Mutations,TwS -118003201,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),320,with Mutations,TwS -101003211,101,[T1] Newly diagnosed Pca ,321,with Age below 55,TwS -102003211,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),321,with Age below 55,TwS -103003211,103,[T2] PCa treated right away,321,with Age below 55,TwS -104003211,104,[T2a] PCa treated right away (biopsy or PSA GT 50),321,with Age below 55,TwS -105003211,105,[T3] PCa under conservative management,321,with Age below 55,TwS -106003211,106,[T3.1] PCa high/intermediate risk conservative management,321,with Age below 55,TwS -107003211,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),321,with Age below 55,TwS -108003211,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,321,with Age below 55,TwS -109003211,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),321,with Age below 55,TwS -110003211,110,[T3.3] PCa low risk grade conservative management and intense monitoring,321,with Age below 55,TwS -111003211,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),321,with Age below 55,TwS -112003211,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),321,with Age below 55,TwS -113003211,113,[T4] PCa treated after conservative management ,321,with Age below 55,TwS -114003211,114,[T4.1] Delayed Curative Management,321,with Age below 55,TwS -115003211,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),321,with Age below 55,TwS -116003211,116,[T4.2] Delayed Palliative Management,321,with Age below 55,TwS -117003211,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),321,with Age below 55,TwS -118003211,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),321,with Age below 55,TwS -101003221,101,[T1] Newly diagnosed Pca ,322,with Age 55-80,TwS -102003221,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),322,with Age 55-80,TwS -103003221,103,[T2] PCa treated right away,322,with Age 55-80,TwS -104003221,104,[T2a] PCa treated right away (biopsy or PSA GT 50),322,with Age 55-80,TwS -105003221,105,[T3] PCa under conservative management,322,with Age 55-80,TwS -106003221,106,[T3.1] PCa high/intermediate risk conservative management,322,with Age 55-80,TwS -107003221,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),322,with Age 55-80,TwS -108003221,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,322,with Age 55-80,TwS -109003221,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),322,with Age 55-80,TwS -110003221,110,[T3.3] PCa low risk grade conservative management and intense monitoring,322,with Age 55-80,TwS -111003221,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),322,with Age 55-80,TwS -112003221,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),322,with Age 55-80,TwS -113003221,113,[T4] PCa treated after conservative management ,322,with Age 55-80,TwS -114003221,114,[T4.1] Delayed Curative Management,322,with Age 55-80,TwS -115003221,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),322,with Age 55-80,TwS -116003221,116,[T4.2] Delayed Palliative Management,322,with Age 55-80,TwS -117003221,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),322,with Age 55-80,TwS -118003221,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),322,with Age 55-80,TwS -101003231,101,[T1] Newly diagnosed Pca ,323,with Age above 80,TwS -102003231,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),323,with Age above 80,TwS -103003231,103,[T2] PCa treated right away,323,with Age above 80,TwS -104003231,104,[T2a] PCa treated right away (biopsy or PSA GT 50),323,with Age above 80,TwS -105003231,105,[T3] PCa under conservative management,323,with Age above 80,TwS -106003231,106,[T3.1] PCa high/intermediate risk conservative management,323,with Age above 80,TwS -107003231,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),323,with Age above 80,TwS -108003231,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,323,with Age above 80,TwS -109003231,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),323,with Age above 80,TwS -110003231,110,[T3.3] PCa low risk grade conservative management and intense monitoring,323,with Age above 80,TwS -111003231,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),323,with Age above 80,TwS -112003231,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),323,with Age above 80,TwS -113003231,113,[T4] PCa treated after conservative management ,323,with Age above 80,TwS -114003231,114,[T4.1] Delayed Curative Management,323,with Age above 80,TwS -115003231,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),323,with Age above 80,TwS -116003231,116,[T4.2] Delayed Palliative Management,323,with Age above 80,TwS -117003231,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),323,with Age above 80,TwS -118003231,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),323,with Age above 80,TwS -101003241,101,[T1] Newly diagnosed Pca ,324,with Charlson Comorbidity Index (cut off 0),TwS -102003241,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),324,with Charlson Comorbidity Index (cut off 0),TwS -103003241,103,[T2] PCa treated right away,324,with Charlson Comorbidity Index (cut off 0),TwS -104003241,104,[T2a] PCa treated right away (biopsy or PSA GT 50),324,with Charlson Comorbidity Index (cut off 0),TwS -105003241,105,[T3] PCa under conservative management,324,with Charlson Comorbidity Index (cut off 0),TwS -106003241,106,[T3.1] PCa high/intermediate risk conservative management,324,with Charlson Comorbidity Index (cut off 0),TwS -107003241,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),324,with Charlson Comorbidity Index (cut off 0),TwS -108003241,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,324,with Charlson Comorbidity Index (cut off 0),TwS -109003241,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),324,with Charlson Comorbidity Index (cut off 0),TwS -110003241,110,[T3.3] PCa low risk grade conservative management and intense monitoring,324,with Charlson Comorbidity Index (cut off 0),TwS -111003241,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),324,with Charlson Comorbidity Index (cut off 0),TwS -112003241,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),324,with Charlson Comorbidity Index (cut off 0),TwS -113003241,113,[T4] PCa treated after conservative management ,324,with Charlson Comorbidity Index (cut off 0),TwS -114003241,114,[T4.1] Delayed Curative Management,324,with Charlson Comorbidity Index (cut off 0),TwS -115003241,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),324,with Charlson Comorbidity Index (cut off 0),TwS -116003241,116,[T4.2] Delayed Palliative Management,324,with Charlson Comorbidity Index (cut off 0),TwS -117003241,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),324,with Charlson Comorbidity Index (cut off 0),TwS -118003241,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),324,with Charlson Comorbidity Index (cut off 0),TwS -101003251,101,[T1] Newly diagnosed Pca ,325,with Charlson Comorbidity Index (cut off 1),TwS -102003251,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),325,with Charlson Comorbidity Index (cut off 1),TwS -103003251,103,[T2] PCa treated right away,325,with Charlson Comorbidity Index (cut off 1),TwS -104003251,104,[T2a] PCa treated right away (biopsy or PSA GT 50),325,with Charlson Comorbidity Index (cut off 1),TwS -105003251,105,[T3] PCa under conservative management,325,with Charlson Comorbidity Index (cut off 1),TwS -106003251,106,[T3.1] PCa high/intermediate risk conservative management,325,with Charlson Comorbidity Index (cut off 1),TwS -107003251,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),325,with Charlson Comorbidity Index (cut off 1),TwS -108003251,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,325,with Charlson Comorbidity Index (cut off 1),TwS -109003251,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),325,with Charlson Comorbidity Index (cut off 1),TwS -110003251,110,[T3.3] PCa low risk grade conservative management and intense monitoring,325,with Charlson Comorbidity Index (cut off 1),TwS -111003251,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),325,with Charlson Comorbidity Index (cut off 1),TwS -112003251,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),325,with Charlson Comorbidity Index (cut off 1),TwS -113003251,113,[T4] PCa treated after conservative management ,325,with Charlson Comorbidity Index (cut off 1),TwS -114003251,114,[T4.1] Delayed Curative Management,325,with Charlson Comorbidity Index (cut off 1),TwS -115003251,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),325,with Charlson Comorbidity Index (cut off 1),TwS -116003251,116,[T4.2] Delayed Palliative Management,325,with Charlson Comorbidity Index (cut off 1),TwS -117003251,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),325,with Charlson Comorbidity Index (cut off 1),TwS -118003251,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),325,with Charlson Comorbidity Index (cut off 1),TwS -101003261,101,[T1] Newly diagnosed Pca ,326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -102003261,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -103003261,103,[T2] PCa treated right away,326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -104003261,104,[T2a] PCa treated right away (biopsy or PSA GT 50),326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -105003261,105,[T3] PCa under conservative management,326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -106003261,106,[T3.1] PCa high/intermediate risk conservative management,326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -107003261,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -108003261,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -109003261,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -110003261,110,[T3.3] PCa low risk grade conservative management and intense monitoring,326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -111003261,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -112003261,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -113003261,113,[T4] PCa treated after conservative management ,326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -114003261,114,[T4.1] Delayed Curative Management,326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -115003261,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -116003261,116,[T4.2] Delayed Palliative Management,326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -117003261,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -118003261,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),326,with Charlson Comorbidity Index (cut off greater or equals 2 ),TwS -101003271,101,[T1] Newly diagnosed Pca ,327,with Other malignancies,TwS -102003271,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),327,with Other malignancies,TwS -103003271,103,[T2] PCa treated right away,327,with Other malignancies,TwS -104003271,104,[T2a] PCa treated right away (biopsy or PSA GT 50),327,with Other malignancies,TwS -105003271,105,[T3] PCa under conservative management,327,with Other malignancies,TwS -106003271,106,[T3.1] PCa high/intermediate risk conservative management,327,with Other malignancies,TwS -107003271,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),327,with Other malignancies,TwS -108003271,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,327,with Other malignancies,TwS -109003271,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),327,with Other malignancies,TwS -110003271,110,[T3.3] PCa low risk grade conservative management and intense monitoring,327,with Other malignancies,TwS -111003271,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),327,with Other malignancies,TwS -112003271,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),327,with Other malignancies,TwS -113003271,113,[T4] PCa treated after conservative management ,327,with Other malignancies,TwS -114003271,114,[T4.1] Delayed Curative Management,327,with Other malignancies,TwS -115003271,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),327,with Other malignancies,TwS -116003271,116,[T4.2] Delayed Palliative Management,327,with Other malignancies,TwS -117003271,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),327,with Other malignancies,TwS -118003271,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),327,with Other malignancies,TwS -101003281,101,[T1] Newly diagnosed Pca ,328,with Total Cardiovascular Disease Event,TwS -102003281,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),328,with Total Cardiovascular Disease Event,TwS -103003281,103,[T2] PCa treated right away,328,with Total Cardiovascular Disease Event,TwS -104003281,104,[T2a] PCa treated right away (biopsy or PSA GT 50),328,with Total Cardiovascular Disease Event,TwS -105003281,105,[T3] PCa under conservative management,328,with Total Cardiovascular Disease Event,TwS -106003281,106,[T3.1] PCa high/intermediate risk conservative management,328,with Total Cardiovascular Disease Event,TwS -107003281,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),328,with Total Cardiovascular Disease Event,TwS -108003281,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,328,with Total Cardiovascular Disease Event,TwS -109003281,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),328,with Total Cardiovascular Disease Event,TwS -110003281,110,[T3.3] PCa low risk grade conservative management and intense monitoring,328,with Total Cardiovascular Disease Event,TwS -111003281,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),328,with Total Cardiovascular Disease Event,TwS -112003281,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),328,with Total Cardiovascular Disease Event,TwS -113003281,113,[T4] PCa treated after conservative management ,328,with Total Cardiovascular Disease Event,TwS -114003281,114,[T4.1] Delayed Curative Management,328,with Total Cardiovascular Disease Event,TwS -115003281,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),328,with Total Cardiovascular Disease Event,TwS -116003281,116,[T4.2] Delayed Palliative Management,328,with Total Cardiovascular Disease Event,TwS -117003281,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),328,with Total Cardiovascular Disease Event,TwS -118003281,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),328,with Total Cardiovascular Disease Event,TwS -101003291,101,[T1] Newly diagnosed Pca ,329,with Stroke,TwS -102003291,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),329,with Stroke,TwS -103003291,103,[T2] PCa treated right away,329,with Stroke,TwS -104003291,104,[T2a] PCa treated right away (biopsy or PSA GT 50),329,with Stroke,TwS -105003291,105,[T3] PCa under conservative management,329,with Stroke,TwS -106003291,106,[T3.1] PCa high/intermediate risk conservative management,329,with Stroke,TwS -107003291,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),329,with Stroke,TwS -108003291,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,329,with Stroke,TwS -109003291,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),329,with Stroke,TwS -110003291,110,[T3.3] PCa low risk grade conservative management and intense monitoring,329,with Stroke,TwS -111003291,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),329,with Stroke,TwS -112003291,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),329,with Stroke,TwS -113003291,113,[T4] PCa treated after conservative management ,329,with Stroke,TwS -114003291,114,[T4.1] Delayed Curative Management,329,with Stroke,TwS -115003291,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),329,with Stroke,TwS -116003291,116,[T4.2] Delayed Palliative Management,329,with Stroke,TwS -117003291,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),329,with Stroke,TwS -118003291,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),329,with Stroke,TwS -101003301,101,[T1] Newly diagnosed Pca ,330,with Type 2 Diabetes,TwS -102003301,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),330,with Type 2 Diabetes,TwS -103003301,103,[T2] PCa treated right away,330,with Type 2 Diabetes,TwS -104003301,104,[T2a] PCa treated right away (biopsy or PSA GT 50),330,with Type 2 Diabetes,TwS -105003301,105,[T3] PCa under conservative management,330,with Type 2 Diabetes,TwS -106003301,106,[T3.1] PCa high/intermediate risk conservative management,330,with Type 2 Diabetes,TwS -107003301,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),330,with Type 2 Diabetes,TwS -108003301,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,330,with Type 2 Diabetes,TwS -109003301,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),330,with Type 2 Diabetes,TwS -110003301,110,[T3.3] PCa low risk grade conservative management and intense monitoring,330,with Type 2 Diabetes,TwS -111003301,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),330,with Type 2 Diabetes,TwS -112003301,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),330,with Type 2 Diabetes,TwS -113003301,113,[T4] PCa treated after conservative management ,330,with Type 2 Diabetes,TwS -114003301,114,[T4.1] Delayed Curative Management,330,with Type 2 Diabetes,TwS -115003301,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),330,with Type 2 Diabetes,TwS -116003301,116,[T4.2] Delayed Palliative Management,330,with Type 2 Diabetes,TwS -117003301,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),330,with Type 2 Diabetes,TwS -118003301,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),330,with Type 2 Diabetes,TwS -101003311,101,[T1] Newly diagnosed Pca ,331,with Hypertension,TwS -102003311,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),331,with Hypertension,TwS -103003311,103,[T2] PCa treated right away,331,with Hypertension,TwS -104003311,104,[T2a] PCa treated right away (biopsy or PSA GT 50),331,with Hypertension,TwS -105003311,105,[T3] PCa under conservative management,331,with Hypertension,TwS -106003311,106,[T3.1] PCa high/intermediate risk conservative management,331,with Hypertension,TwS -107003311,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),331,with Hypertension,TwS -108003311,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,331,with Hypertension,TwS -109003311,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),331,with Hypertension,TwS -110003311,110,[T3.3] PCa low risk grade conservative management and intense monitoring,331,with Hypertension,TwS -111003311,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),331,with Hypertension,TwS -112003311,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),331,with Hypertension,TwS -113003311,113,[T4] PCa treated after conservative management ,331,with Hypertension,TwS -114003311,114,[T4.1] Delayed Curative Management,331,with Hypertension,TwS -115003311,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),331,with Hypertension,TwS -116003311,116,[T4.2] Delayed Palliative Management,331,with Hypertension,TwS -117003311,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),331,with Hypertension,TwS -118003311,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),331,with Hypertension,TwS -101003321,101,[T1] Newly diagnosed Pca ,332,with Obesity,TwS -102003321,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),332,with Obesity,TwS -103003321,103,[T2] PCa treated right away,332,with Obesity,TwS -104003321,104,[T2a] PCa treated right away (biopsy or PSA GT 50),332,with Obesity,TwS -105003321,105,[T3] PCa under conservative management,332,with Obesity,TwS -106003321,106,[T3.1] PCa high/intermediate risk conservative management,332,with Obesity,TwS -107003321,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),332,with Obesity,TwS -108003321,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,332,with Obesity,TwS -109003321,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),332,with Obesity,TwS -110003321,110,[T3.3] PCa low risk grade conservative management and intense monitoring,332,with Obesity,TwS -111003321,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),332,with Obesity,TwS -112003321,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),332,with Obesity,TwS -113003321,113,[T4] PCa treated after conservative management ,332,with Obesity,TwS -114003321,114,[T4.1] Delayed Curative Management,332,with Obesity,TwS -115003321,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),332,with Obesity,TwS -116003321,116,[T4.2] Delayed Palliative Management,332,with Obesity,TwS -117003321,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),332,with Obesity,TwS -118003321,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),332,with Obesity,TwS -101003331,101,[T1] Newly diagnosed Pca ,333,with VTE,TwS -102003331,102,[T1a] Newly diagnosed Pca (biopsy or PSA GT 50),333,with VTE,TwS -103003331,103,[T2] PCa treated right away,333,with VTE,TwS -104003331,104,[T2a] PCa treated right away (biopsy or PSA GT 50),333,with VTE,TwS -105003331,105,[T3] PCa under conservative management,333,with VTE,TwS -106003331,106,[T3.1] PCa high/intermediate risk conservative management,333,with VTE,TwS -107003331,107,[T3.1a] PCa high/intermediate risk conservative managemetn (biopsy or PSA GT 50),333,with VTE,TwS -108003331,108,[T3.2] PCa low risk grade conservative management and no intense monitoring,333,with VTE,TwS -109003331,109,[T3.2a] PCa low risk grade conservative management and no intense monitoring (biopsy or PSA GT 50),333,with VTE,TwS -110003331,110,[T3.3] PCa low risk grade conservative management and intense monitoring,333,with VTE,TwS -111003331,111,[T3.3a] PCa low risk grade conservative management and intense monitoring (biopsy or PSA GT 50),333,with VTE,TwS -112003331,112,[T3a] PCa under conservative management (biopsy or PSA GT 50),333,with VTE,TwS -113003331,113,[T4] PCa treated after conservative management ,333,with VTE,TwS -114003331,114,[T4.1] Delayed Curative Management,333,with VTE,TwS -115003331,115,[T4.1a] Delayed Curative Management (biopsy or PSA GT 50),333,with VTE,TwS -116003331,116,[T4.2] Delayed Palliative Management,333,with VTE,TwS -117003331,117,[T4.2a] Delayed Palliative Management (biopsy or PSA GT 50),333,with VTE,TwS -118003331,118,[T4a] PCa treated after conservative management (biopsy or PSA GT 50),333,with VTE,TwS \ No newline at end of file +101,101,[PIONEER T1] Newly diagnosed Pca ,0,All,Target +103,103,[PIONEER T2] PCa treated right away,0,All,Target +111,111,[PIONEER T3] PCa under conservative management,0,All,Target +117,117,[PIONEER T4] PCa treated after conservative management ,0,All,Target +105,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,0,All,Target +107,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,0,All,Target +109,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,0,All,Target +113,113,[PIONEER T4.1] Delayed Curative Management,0,All,Target +115,115,[PIONEER T4.2] Delayed Palliative Management,0,All,Target +102,102,[PIONEER T1a] Newly diagnosed Pca_broad,0,All,Target +104,104,[PIONEER T2a] PCa treated right away_broad,0,All,Target +112,112,[PIONEER T3a] PCa under conservative management_broad,0,All,Target +118,118,[PIONEER T4a] PCa treated after conservative management_broad,0,All,Target +106,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,0,All,Target +108,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,0,All,Target +110,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,0,All,Target +114,114,[PIONEER T4.1a] Delayed Curative Management_broad,0,All,Target +116,116,[PIONEER T4.2a] Delayed Palliative Management_broad,0,All,Target +119,119,[PIONEER T5] Symptom post conservative management ,0,All,Target +120,120,[PIONEER T5a] Symptom post conservative management_broad,0,All,Target +101003012,101,[PIONEER T1] Newly diagnosed Pca ,301,without [PIONEER S1] EAU High Risk,TwoS +102003012,102,[PIONEER T1a] Newly diagnosed Pca_broad,301,without [PIONEER S1] EAU High Risk,TwoS +103003012,103,[PIONEER T2] PCa treated right away,301,without [PIONEER S1] EAU High Risk,TwoS +104003012,104,[PIONEER T2a] PCa treated right away_broad,301,without [PIONEER S1] EAU High Risk,TwoS +105003012,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,301,without [PIONEER S1] EAU High Risk,TwoS +106003012,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,301,without [PIONEER S1] EAU High Risk,TwoS +107003012,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,301,without [PIONEER S1] EAU High Risk,TwoS +108003012,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,301,without [PIONEER S1] EAU High Risk,TwoS +109003012,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,301,without [PIONEER S1] EAU High Risk,TwoS +110003012,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,301,without [PIONEER S1] EAU High Risk,TwoS +111003012,111,[PIONEER T3] PCa under conservative management,301,without [PIONEER S1] EAU High Risk,TwoS +112003012,112,[PIONEER T3a] PCa under conservative management_broad,301,without [PIONEER S1] EAU High Risk,TwoS +113003012,113,[PIONEER T4.1] Delayed Curative Management,301,without [PIONEER S1] EAU High Risk,TwoS +114003012,114,[PIONEER T4.1a] Delayed Curative Management_broad,301,without [PIONEER S1] EAU High Risk,TwoS +115003012,115,[PIONEER T4.2] Delayed Palliative Management,301,without [PIONEER S1] EAU High Risk,TwoS +116003012,116,[PIONEER T4.2a] Delayed Palliative Management_broad,301,without [PIONEER S1] EAU High Risk,TwoS +117003012,117,[PIONEER T4] PCa treated after conservative management ,301,without [PIONEER S1] EAU High Risk,TwoS +118003012,118,[PIONEER T4a] PCa treated after conservative management_broad,301,without [PIONEER S1] EAU High Risk,TwoS +119003012,119,[PIONEER T5] Symptom post conservative management ,301,without [PIONEER S1] EAU High Risk,TwoS +120003012,120,[PIONEER T5a] Symptom post conservative management_broad,301,without [PIONEER S1] EAU High Risk,TwoS +101003022,101,[PIONEER T1] Newly diagnosed Pca ,302,without [PIONEER S2] EAU Low Risk,TwoS +102003022,102,[PIONEER T1a] Newly diagnosed Pca_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +103003022,103,[PIONEER T2] PCa treated right away,302,without [PIONEER S2] EAU Low Risk,TwoS +104003022,104,[PIONEER T2a] PCa treated right away_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +105003022,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,302,without [PIONEER S2] EAU Low Risk,TwoS +106003022,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +107003022,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,302,without [PIONEER S2] EAU Low Risk,TwoS +108003022,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +109003022,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,302,without [PIONEER S2] EAU Low Risk,TwoS +110003022,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +111003022,111,[PIONEER T3] PCa under conservative management,302,without [PIONEER S2] EAU Low Risk,TwoS +112003022,112,[PIONEER T3a] PCa under conservative management_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +113003022,113,[PIONEER T4.1] Delayed Curative Management,302,without [PIONEER S2] EAU Low Risk,TwoS +114003022,114,[PIONEER T4.1a] Delayed Curative Management_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +115003022,115,[PIONEER T4.2] Delayed Palliative Management,302,without [PIONEER S2] EAU Low Risk,TwoS +116003022,116,[PIONEER T4.2a] Delayed Palliative Management_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +117003022,117,[PIONEER T4] PCa treated after conservative management ,302,without [PIONEER S2] EAU Low Risk,TwoS +118003022,118,[PIONEER T4a] PCa treated after conservative management_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +119003022,119,[PIONEER T5] Symptom post conservative management ,302,without [PIONEER S2] EAU Low Risk,TwoS +120003022,120,[PIONEER T5a] Symptom post conservative management_broad,302,without [PIONEER S2] EAU Low Risk,TwoS +101003032,101,[PIONEER T1] Newly diagnosed Pca ,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +102003032,102,[PIONEER T1a] Newly diagnosed Pca_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +103003032,103,[PIONEER T2] PCa treated right away,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +104003032,104,[PIONEER T2a] PCa treated right away_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +105003032,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +106003032,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +107003032,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +108003032,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +109003032,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +110003032,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +111003032,111,[PIONEER T3] PCa under conservative management,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +112003032,112,[PIONEER T3a] PCa under conservative management_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +113003032,113,[PIONEER T4.1] Delayed Curative Management,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +114003032,114,[PIONEER T4.1a] Delayed Curative Management_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +115003032,115,[PIONEER T4.2] Delayed Palliative Management,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +116003032,116,[PIONEER T4.2a] Delayed Palliative Management_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +117003032,117,[PIONEER T4] PCa treated after conservative management ,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +118003032,118,[PIONEER T4a] PCa treated after conservative management_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +119003032,119,[PIONEER T5] Symptom post conservative management ,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +120003032,120,[PIONEER T5a] Symptom post conservative management_broad,303,without [PIONEER S3] EAU Intermediate Risk,TwoS +101003042,101,[PIONEER T1] Newly diagnosed Pca ,304,without [PIONEER S4] Metastatic PCa,TwoS +102003042,102,[PIONEER T1a] Newly diagnosed Pca_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +103003042,103,[PIONEER T2] PCa treated right away,304,without [PIONEER S4] Metastatic PCa,TwoS +104003042,104,[PIONEER T2a] PCa treated right away_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +105003042,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,304,without [PIONEER S4] Metastatic PCa,TwoS +106003042,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +107003042,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,304,without [PIONEER S4] Metastatic PCa,TwoS +108003042,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +109003042,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,304,without [PIONEER S4] Metastatic PCa,TwoS +110003042,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +111003042,111,[PIONEER T3] PCa under conservative management,304,without [PIONEER S4] Metastatic PCa,TwoS +112003042,112,[PIONEER T3a] PCa under conservative management_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +113003042,113,[PIONEER T4.1] Delayed Curative Management,304,without [PIONEER S4] Metastatic PCa,TwoS +114003042,114,[PIONEER T4.1a] Delayed Curative Management_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +115003042,115,[PIONEER T4.2] Delayed Palliative Management,304,without [PIONEER S4] Metastatic PCa,TwoS +116003042,116,[PIONEER T4.2a] Delayed Palliative Management_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +117003042,117,[PIONEER T4] PCa treated after conservative management ,304,without [PIONEER S4] Metastatic PCa,TwoS +118003042,118,[PIONEER T4a] PCa treated after conservative management_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +119003042,119,[PIONEER T5] Symptom post conservative management ,304,without [PIONEER S4] Metastatic PCa,TwoS +120003042,120,[PIONEER T5a] Symptom post conservative management_broad,304,without [PIONEER S4] Metastatic PCa,TwoS +101003052,101,[PIONEER T1] Newly diagnosed Pca ,305,without [PIONEER S5] Locally Advanced PCa,TwoS +102003052,102,[PIONEER T1a] Newly diagnosed Pca_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +103003052,103,[PIONEER T2] PCa treated right away,305,without [PIONEER S5] Locally Advanced PCa,TwoS +104003052,104,[PIONEER T2a] PCa treated right away_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +105003052,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,305,without [PIONEER S5] Locally Advanced PCa,TwoS +106003052,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +107003052,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,305,without [PIONEER S5] Locally Advanced PCa,TwoS +108003052,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +109003052,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,305,without [PIONEER S5] Locally Advanced PCa,TwoS +110003052,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +111003052,111,[PIONEER T3] PCa under conservative management,305,without [PIONEER S5] Locally Advanced PCa,TwoS +112003052,112,[PIONEER T3a] PCa under conservative management_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +113003052,113,[PIONEER T4.1] Delayed Curative Management,305,without [PIONEER S5] Locally Advanced PCa,TwoS +114003052,114,[PIONEER T4.1a] Delayed Curative Management_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +115003052,115,[PIONEER T4.2] Delayed Palliative Management,305,without [PIONEER S5] Locally Advanced PCa,TwoS +116003052,116,[PIONEER T4.2a] Delayed Palliative Management_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +117003052,117,[PIONEER T4] PCa treated after conservative management ,305,without [PIONEER S5] Locally Advanced PCa,TwoS +118003052,118,[PIONEER T4a] PCa treated after conservative management_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +119003052,119,[PIONEER T5] Symptom post conservative management ,305,without [PIONEER S5] Locally Advanced PCa,TwoS +120003052,120,[PIONEER T5a] Symptom post conservative management_broad,305,without [PIONEER S5] Locally Advanced PCa,TwoS +101003062,101,[PIONEER T1] Newly diagnosed Pca ,306,without [PIONEER S6] localized PCa,TwoS +102003062,102,[PIONEER T1a] Newly diagnosed Pca_broad,306,without [PIONEER S6] localized PCa,TwoS +103003062,103,[PIONEER T2] PCa treated right away,306,without [PIONEER S6] localized PCa,TwoS +104003062,104,[PIONEER T2a] PCa treated right away_broad,306,without [PIONEER S6] localized PCa,TwoS +105003062,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,306,without [PIONEER S6] localized PCa,TwoS +106003062,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,306,without [PIONEER S6] localized PCa,TwoS +107003062,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,306,without [PIONEER S6] localized PCa,TwoS +108003062,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,306,without [PIONEER S6] localized PCa,TwoS +109003062,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,306,without [PIONEER S6] localized PCa,TwoS +110003062,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,306,without [PIONEER S6] localized PCa,TwoS +111003062,111,[PIONEER T3] PCa under conservative management,306,without [PIONEER S6] localized PCa,TwoS +112003062,112,[PIONEER T3a] PCa under conservative management_broad,306,without [PIONEER S6] localized PCa,TwoS +113003062,113,[PIONEER T4.1] Delayed Curative Management,306,without [PIONEER S6] localized PCa,TwoS +114003062,114,[PIONEER T4.1a] Delayed Curative Management_broad,306,without [PIONEER S6] localized PCa,TwoS +115003062,115,[PIONEER T4.2] Delayed Palliative Management,306,without [PIONEER S6] localized PCa,TwoS +116003062,116,[PIONEER T4.2a] Delayed Palliative Management_broad,306,without [PIONEER S6] localized PCa,TwoS +117003062,117,[PIONEER T4] PCa treated after conservative management ,306,without [PIONEER S6] localized PCa,TwoS +118003062,118,[PIONEER T4a] PCa treated after conservative management_broad,306,without [PIONEER S6] localized PCa,TwoS +119003062,119,[PIONEER T5] Symptom post conservative management ,306,without [PIONEER S6] localized PCa,TwoS +120003062,120,[PIONEER T5a] Symptom post conservative management_broad,306,without [PIONEER S6] localized PCa,TwoS +101003072,101,[PIONEER T1] Newly diagnosed Pca ,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +102003072,102,[PIONEER T1a] Newly diagnosed Pca_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +103003072,103,[PIONEER T2] PCa treated right away,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +104003072,104,[PIONEER T2a] PCa treated right away_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +105003072,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +106003072,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +107003072,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +108003072,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +109003072,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +110003072,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +111003072,111,[PIONEER T3] PCa under conservative management,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +112003072,112,[PIONEER T3a] PCa under conservative management_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +113003072,113,[PIONEER T4.1] Delayed Curative Management,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +114003072,114,[PIONEER T4.1a] Delayed Curative Management_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +115003072,115,[PIONEER T4.2] Delayed Palliative Management,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +116003072,116,[PIONEER T4.2a] Delayed Palliative Management_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +117003072,117,[PIONEER T4] PCa treated after conservative management ,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +118003072,118,[PIONEER T4a] PCa treated after conservative management_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +119003072,119,[PIONEER T5] Symptom post conservative management ,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +120003072,120,[PIONEER T5a] Symptom post conservative management_broad,307,without [PIONEER S7] PSA >20 at Diagnosis,TwoS +101003082,101,[PIONEER T1] Newly diagnosed Pca ,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +102003082,102,[PIONEER T1a] Newly diagnosed Pca_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +103003082,103,[PIONEER T2] PCa treated right away,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +104003082,104,[PIONEER T2a] PCa treated right away_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +105003082,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +106003082,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +107003082,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +108003082,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +109003082,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +110003082,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +111003082,111,[PIONEER T3] PCa under conservative management,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +112003082,112,[PIONEER T3a] PCa under conservative management_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +113003082,113,[PIONEER T4.1] Delayed Curative Management,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +114003082,114,[PIONEER T4.1a] Delayed Curative Management_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +115003082,115,[PIONEER T4.2] Delayed Palliative Management,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +116003082,116,[PIONEER T4.2a] Delayed Palliative Management_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +117003082,117,[PIONEER T4] PCa treated after conservative management ,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +118003082,118,[PIONEER T4a] PCa treated after conservative management_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +119003082,119,[PIONEER T5] Symptom post conservative management ,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +120003082,120,[PIONEER T5a] Symptom post conservative management_broad,308,without [PIONEER S8] PSA <10 at Diagnosis,TwoS +101003092,101,[PIONEER T1] Newly diagnosed Pca ,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +102003092,102,[PIONEER T1a] Newly diagnosed Pca_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +103003092,103,[PIONEER T2] PCa treated right away,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +104003092,104,[PIONEER T2a] PCa treated right away_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +105003092,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +106003092,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +107003092,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +108003092,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +109003092,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +110003092,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +111003092,111,[PIONEER T3] PCa under conservative management,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +112003092,112,[PIONEER T3a] PCa under conservative management_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +113003092,113,[PIONEER T4.1] Delayed Curative Management,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +114003092,114,[PIONEER T4.1a] Delayed Curative Management_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +115003092,115,[PIONEER T4.2] Delayed Palliative Management,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +116003092,116,[PIONEER T4.2a] Delayed Palliative Management_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +117003092,117,[PIONEER T4] PCa treated after conservative management ,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +118003092,118,[PIONEER T4a] PCa treated after conservative management_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +119003092,119,[PIONEER T5] Symptom post conservative management ,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +120003092,120,[PIONEER T5a] Symptom post conservative management_broad,309,without [PIONEER S9] PSA 10-20 at Diagnosis,TwoS +101003102,101,[PIONEER T1] Newly diagnosed Pca ,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +102003102,102,[PIONEER T1a] Newly diagnosed Pca_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +103003102,103,[PIONEER T2] PCa treated right away,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +104003102,104,[PIONEER T2a] PCa treated right away_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +105003102,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +106003102,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +107003102,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +108003102,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +109003102,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +110003102,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +111003102,111,[PIONEER T3] PCa under conservative management,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +112003102,112,[PIONEER T3a] PCa under conservative management_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +113003102,113,[PIONEER T4.1] Delayed Curative Management,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +114003102,114,[PIONEER T4.1a] Delayed Curative Management_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +115003102,115,[PIONEER T4.2] Delayed Palliative Management,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +116003102,116,[PIONEER T4.2a] Delayed Palliative Management_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +117003102,117,[PIONEER T4] PCa treated after conservative management ,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +118003102,118,[PIONEER T4a] PCa treated after conservative management_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +119003102,119,[PIONEER T5] Symptom post conservative management ,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +120003102,120,[PIONEER T5a] Symptom post conservative management_broad,310,without [PIONEER S10] Stage cT1 at Dx,TwoS +101003112,101,[PIONEER T1] Newly diagnosed Pca ,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +102003112,102,[PIONEER T1a] Newly diagnosed Pca_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +103003112,103,[PIONEER T2] PCa treated right away,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +104003112,104,[PIONEER T2a] PCa treated right away_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +105003112,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +106003112,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +107003112,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +108003112,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +109003112,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +110003112,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +111003112,111,[PIONEER T3] PCa under conservative management,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +112003112,112,[PIONEER T3a] PCa under conservative management_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +113003112,113,[PIONEER T4.1] Delayed Curative Management,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +114003112,114,[PIONEER T4.1a] Delayed Curative Management_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +115003112,115,[PIONEER T4.2] Delayed Palliative Management,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +116003112,116,[PIONEER T4.2a] Delayed Palliative Management_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +117003112,117,[PIONEER T4] PCa treated after conservative management ,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +118003112,118,[PIONEER T4a] PCa treated after conservative management_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +119003112,119,[PIONEER T5] Symptom post conservative management ,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +120003112,120,[PIONEER T5a] Symptom post conservative management_broad,311,without [PIONEER S11] Stage cT2 at Dx,TwoS +101003122,101,[PIONEER T1] Newly diagnosed Pca ,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +102003122,102,[PIONEER T1a] Newly diagnosed Pca_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +103003122,103,[PIONEER T2] PCa treated right away,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +104003122,104,[PIONEER T2a] PCa treated right away_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +105003122,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +106003122,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +107003122,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +108003122,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +109003122,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +110003122,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +111003122,111,[PIONEER T3] PCa under conservative management,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +112003122,112,[PIONEER T3a] PCa under conservative management_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +113003122,113,[PIONEER T4.1] Delayed Curative Management,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +114003122,114,[PIONEER T4.1a] Delayed Curative Management_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +115003122,115,[PIONEER T4.2] Delayed Palliative Management,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +116003122,116,[PIONEER T4.2a] Delayed Palliative Management_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +117003122,117,[PIONEER T4] PCa treated after conservative management ,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +118003122,118,[PIONEER T4a] PCa treated after conservative management_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +119003122,119,[PIONEER T5] Symptom post conservative management ,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +120003122,120,[PIONEER T5a] Symptom post conservative management_broad,312,without [PIONEER S12] Stage cT3/cT4 at Dx,TwoS +101003132,101,[PIONEER T1] Newly diagnosed Pca ,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +102003132,102,[PIONEER T1a] Newly diagnosed Pca_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +103003132,103,[PIONEER T2] PCa treated right away,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +104003132,104,[PIONEER T2a] PCa treated right away_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +105003132,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +106003132,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +107003132,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +108003132,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +109003132,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +110003132,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +111003132,111,[PIONEER T3] PCa under conservative management,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +112003132,112,[PIONEER T3a] PCa under conservative management_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +113003132,113,[PIONEER T4.1] Delayed Curative Management,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +114003132,114,[PIONEER T4.1a] Delayed Curative Management_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +115003132,115,[PIONEER T4.2] Delayed Palliative Management,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +116003132,116,[PIONEER T4.2a] Delayed Palliative Management_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +117003132,117,[PIONEER T4] PCa treated after conservative management ,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +118003132,118,[PIONEER T4a] PCa treated after conservative management_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +119003132,119,[PIONEER T5] Symptom post conservative management ,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +120003132,120,[PIONEER T5a] Symptom post conservative management_broad,313,without [PIONEER S13] Physical Therapy/Exercise,TwoS +101003142,101,[PIONEER T1] Newly diagnosed Pca ,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +102003142,102,[PIONEER T1a] Newly diagnosed Pca_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +103003142,103,[PIONEER T2] PCa treated right away,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +104003142,104,[PIONEER T2a] PCa treated right away_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +105003142,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +106003142,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +107003142,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +108003142,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +109003142,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +110003142,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +111003142,111,[PIONEER T3] PCa under conservative management,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +112003142,112,[PIONEER T3a] PCa under conservative management_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +113003142,113,[PIONEER T4.1] Delayed Curative Management,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +114003142,114,[PIONEER T4.1a] Delayed Curative Management_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +115003142,115,[PIONEER T4.2] Delayed Palliative Management,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +116003142,116,[PIONEER T4.2a] Delayed Palliative Management_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +117003142,117,[PIONEER T4] PCa treated after conservative management ,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +118003142,118,[PIONEER T4a] PCa treated after conservative management_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +119003142,119,[PIONEER T5] Symptom post conservative management ,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +120003142,120,[PIONEER T5a] Symptom post conservative management_broad,314,without [PIONEER S14] Grade 1 (GS 2-6),TwoS +101003152,101,[PIONEER T1] Newly diagnosed Pca ,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +102003152,102,[PIONEER T1a] Newly diagnosed Pca_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +103003152,103,[PIONEER T2] PCa treated right away,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +104003152,104,[PIONEER T2a] PCa treated right away_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +105003152,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +106003152,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +107003152,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +108003152,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +109003152,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +110003152,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +111003152,111,[PIONEER T3] PCa under conservative management,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +112003152,112,[PIONEER T3a] PCa under conservative management_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +113003152,113,[PIONEER T4.1] Delayed Curative Management,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +114003152,114,[PIONEER T4.1a] Delayed Curative Management_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +115003152,115,[PIONEER T4.2] Delayed Palliative Management,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +116003152,116,[PIONEER T4.2a] Delayed Palliative Management_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +117003152,117,[PIONEER T4] PCa treated after conservative management ,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +118003152,118,[PIONEER T4a] PCa treated after conservative management_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +119003152,119,[PIONEER T5] Symptom post conservative management ,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +120003152,120,[PIONEER T5a] Symptom post conservative management_broad,315,without [PIONEER S15] Grade 2 (GS 3+4),TwoS +101003162,101,[PIONEER T1] Newly diagnosed Pca ,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +102003162,102,[PIONEER T1a] Newly diagnosed Pca_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +103003162,103,[PIONEER T2] PCa treated right away,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +104003162,104,[PIONEER T2a] PCa treated right away_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +105003162,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +106003162,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +107003162,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +108003162,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +109003162,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +110003162,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +111003162,111,[PIONEER T3] PCa under conservative management,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +112003162,112,[PIONEER T3a] PCa under conservative management_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +113003162,113,[PIONEER T4.1] Delayed Curative Management,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +114003162,114,[PIONEER T4.1a] Delayed Curative Management_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +115003162,115,[PIONEER T4.2] Delayed Palliative Management,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +116003162,116,[PIONEER T4.2a] Delayed Palliative Management_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +117003162,117,[PIONEER T4] PCa treated after conservative management ,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +118003162,118,[PIONEER T4a] PCa treated after conservative management_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +119003162,119,[PIONEER T5] Symptom post conservative management ,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +120003162,120,[PIONEER T5a] Symptom post conservative management_broad,316,without [PIONEER S16] Grade 3 (GS 4+3),TwoS +101003172,101,[PIONEER T1] Newly diagnosed Pca ,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +102003172,102,[PIONEER T1a] Newly diagnosed Pca_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +103003172,103,[PIONEER T2] PCa treated right away,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +104003172,104,[PIONEER T2a] PCa treated right away_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +105003172,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +106003172,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +107003172,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +108003172,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +109003172,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +110003172,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +111003172,111,[PIONEER T3] PCa under conservative management,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +112003172,112,[PIONEER T3a] PCa under conservative management_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +113003172,113,[PIONEER T4.1] Delayed Curative Management,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +114003172,114,[PIONEER T4.1a] Delayed Curative Management_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +115003172,115,[PIONEER T4.2] Delayed Palliative Management,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +116003172,116,[PIONEER T4.2a] Delayed Palliative Management_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +117003172,117,[PIONEER T4] PCa treated after conservative management ,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +118003172,118,[PIONEER T4a] PCa treated after conservative management_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +119003172,119,[PIONEER T5] Symptom post conservative management ,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +120003172,120,[PIONEER T5a] Symptom post conservative management_broad,317,without [PIONEER S17] Grade 4 (GS 8),TwoS +101003182,101,[PIONEER T1] Newly diagnosed Pca ,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +102003182,102,[PIONEER T1a] Newly diagnosed Pca_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +103003182,103,[PIONEER T2] PCa treated right away,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +104003182,104,[PIONEER T2a] PCa treated right away_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +105003182,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +106003182,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +107003182,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +108003182,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +109003182,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +110003182,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +111003182,111,[PIONEER T3] PCa under conservative management,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +112003182,112,[PIONEER T3a] PCa under conservative management_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +113003182,113,[PIONEER T4.1] Delayed Curative Management,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +114003182,114,[PIONEER T4.1a] Delayed Curative Management_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +115003182,115,[PIONEER T4.2] Delayed Palliative Management,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +116003182,116,[PIONEER T4.2a] Delayed Palliative Management_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +117003182,117,[PIONEER T4] PCa treated after conservative management ,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +118003182,118,[PIONEER T4a] PCa treated after conservative management_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +119003182,119,[PIONEER T5] Symptom post conservative management ,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +120003182,120,[PIONEER T5a] Symptom post conservative management_broad,318,without [PIONEER S18] Grade 5 (GS 9-10),TwoS +101003192,101,[PIONEER T1] Newly diagnosed Pca ,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +102003192,102,[PIONEER T1a] Newly diagnosed Pca_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +103003192,103,[PIONEER T2] PCa treated right away,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +104003192,104,[PIONEER T2a] PCa treated right away_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +105003192,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +106003192,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +107003192,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +108003192,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +109003192,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +110003192,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +111003192,111,[PIONEER T3] PCa under conservative management,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +112003192,112,[PIONEER T3a] PCa under conservative management_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +113003192,113,[PIONEER T4.1] Delayed Curative Management,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +114003192,114,[PIONEER T4.1a] Delayed Curative Management_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +115003192,115,[PIONEER T4.2] Delayed Palliative Management,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +116003192,116,[PIONEER T4.2a] Delayed Palliative Management_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +117003192,117,[PIONEER T4] PCa treated after conservative management ,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +118003192,118,[PIONEER T4a] PCa treated after conservative management_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +119003192,119,[PIONEER T5] Symptom post conservative management ,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +120003192,120,[PIONEER T5a] Symptom post conservative management_broad,319,without [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwoS +101003202,101,[PIONEER T1] Newly diagnosed Pca ,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +102003202,102,[PIONEER T1a] Newly diagnosed Pca_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +103003202,103,[PIONEER T2] PCa treated right away,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +104003202,104,[PIONEER T2a] PCa treated right away_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +105003202,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +106003202,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +107003202,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +108003202,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +109003202,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +110003202,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +111003202,111,[PIONEER T3] PCa under conservative management,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +112003202,112,[PIONEER T3a] PCa under conservative management_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +113003202,113,[PIONEER T4.1] Delayed Curative Management,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +114003202,114,[PIONEER T4.1a] Delayed Curative Management_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +115003202,115,[PIONEER T4.2] Delayed Palliative Management,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +116003202,116,[PIONEER T4.2a] Delayed Palliative Management_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +117003202,117,[PIONEER T4] PCa treated after conservative management ,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +118003202,118,[PIONEER T4a] PCa treated after conservative management_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +119003202,119,[PIONEER T5] Symptom post conservative management ,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +120003202,120,[PIONEER T5a] Symptom post conservative management_broad,320,"without [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwoS +101003212,101,[PIONEER T1] Newly diagnosed Pca ,321,without [PIONEER S21] Age at diagnosis <55,TwoS +102003212,102,[PIONEER T1a] Newly diagnosed Pca_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +103003212,103,[PIONEER T2] PCa treated right away,321,without [PIONEER S21] Age at diagnosis <55,TwoS +104003212,104,[PIONEER T2a] PCa treated right away_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +105003212,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,321,without [PIONEER S21] Age at diagnosis <55,TwoS +106003212,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +107003212,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,321,without [PIONEER S21] Age at diagnosis <55,TwoS +108003212,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +109003212,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,321,without [PIONEER S21] Age at diagnosis <55,TwoS +110003212,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +111003212,111,[PIONEER T3] PCa under conservative management,321,without [PIONEER S21] Age at diagnosis <55,TwoS +112003212,112,[PIONEER T3a] PCa under conservative management_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +113003212,113,[PIONEER T4.1] Delayed Curative Management,321,without [PIONEER S21] Age at diagnosis <55,TwoS +114003212,114,[PIONEER T4.1a] Delayed Curative Management_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +115003212,115,[PIONEER T4.2] Delayed Palliative Management,321,without [PIONEER S21] Age at diagnosis <55,TwoS +116003212,116,[PIONEER T4.2a] Delayed Palliative Management_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +117003212,117,[PIONEER T4] PCa treated after conservative management ,321,without [PIONEER S21] Age at diagnosis <55,TwoS +118003212,118,[PIONEER T4a] PCa treated after conservative management_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +119003212,119,[PIONEER T5] Symptom post conservative management ,321,without [PIONEER S21] Age at diagnosis <55,TwoS +120003212,120,[PIONEER T5a] Symptom post conservative management_broad,321,without [PIONEER S21] Age at diagnosis <55,TwoS +101003222,101,[PIONEER T1] Newly diagnosed Pca ,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +102003222,102,[PIONEER T1a] Newly diagnosed Pca_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +103003222,103,[PIONEER T2] PCa treated right away,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +104003222,104,[PIONEER T2a] PCa treated right away_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +105003222,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +106003222,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +107003222,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +108003222,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +109003222,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +110003222,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +111003222,111,[PIONEER T3] PCa under conservative management,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +112003222,112,[PIONEER T3a] PCa under conservative management_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +113003222,113,[PIONEER T4.1] Delayed Curative Management,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +114003222,114,[PIONEER T4.1a] Delayed Curative Management_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +115003222,115,[PIONEER T4.2] Delayed Palliative Management,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +116003222,116,[PIONEER T4.2a] Delayed Palliative Management_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +117003222,117,[PIONEER T4] PCa treated after conservative management ,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +118003222,118,[PIONEER T4a] PCa treated after conservative management_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +119003222,119,[PIONEER T5] Symptom post conservative management ,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +120003222,120,[PIONEER T5a] Symptom post conservative management_broad,322,without [PIONEER S22] Age at diagnosis 55-80,TwoS +101003232,101,[PIONEER T1] Newly diagnosed Pca ,323,without [PIONEER S23] Age at diagnosis >80,TwoS +102003232,102,[PIONEER T1a] Newly diagnosed Pca_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +103003232,103,[PIONEER T2] PCa treated right away,323,without [PIONEER S23] Age at diagnosis >80,TwoS +104003232,104,[PIONEER T2a] PCa treated right away_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +105003232,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,323,without [PIONEER S23] Age at diagnosis >80,TwoS +106003232,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +107003232,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,323,without [PIONEER S23] Age at diagnosis >80,TwoS +108003232,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +109003232,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,323,without [PIONEER S23] Age at diagnosis >80,TwoS +110003232,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +111003232,111,[PIONEER T3] PCa under conservative management,323,without [PIONEER S23] Age at diagnosis >80,TwoS +112003232,112,[PIONEER T3a] PCa under conservative management_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +113003232,113,[PIONEER T4.1] Delayed Curative Management,323,without [PIONEER S23] Age at diagnosis >80,TwoS +114003232,114,[PIONEER T4.1a] Delayed Curative Management_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +115003232,115,[PIONEER T4.2] Delayed Palliative Management,323,without [PIONEER S23] Age at diagnosis >80,TwoS +116003232,116,[PIONEER T4.2a] Delayed Palliative Management_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +117003232,117,[PIONEER T4] PCa treated after conservative management ,323,without [PIONEER S23] Age at diagnosis >80,TwoS +118003232,118,[PIONEER T4a] PCa treated after conservative management_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +119003232,119,[PIONEER T5] Symptom post conservative management ,323,without [PIONEER S23] Age at diagnosis >80,TwoS +120003232,120,[PIONEER T5a] Symptom post conservative management_broad,323,without [PIONEER S23] Age at diagnosis >80,TwoS +101003242,101,[PIONEER T1] Newly diagnosed Pca ,324,without [PIONEER S24] Charlson CCI=0,TwoS +102003242,102,[PIONEER T1a] Newly diagnosed Pca_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +103003242,103,[PIONEER T2] PCa treated right away,324,without [PIONEER S24] Charlson CCI=0,TwoS +104003242,104,[PIONEER T2a] PCa treated right away_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +105003242,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,324,without [PIONEER S24] Charlson CCI=0,TwoS +106003242,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +107003242,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,324,without [PIONEER S24] Charlson CCI=0,TwoS +108003242,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +109003242,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,324,without [PIONEER S24] Charlson CCI=0,TwoS +110003242,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +111003242,111,[PIONEER T3] PCa under conservative management,324,without [PIONEER S24] Charlson CCI=0,TwoS +112003242,112,[PIONEER T3a] PCa under conservative management_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +113003242,113,[PIONEER T4.1] Delayed Curative Management,324,without [PIONEER S24] Charlson CCI=0,TwoS +114003242,114,[PIONEER T4.1a] Delayed Curative Management_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +115003242,115,[PIONEER T4.2] Delayed Palliative Management,324,without [PIONEER S24] Charlson CCI=0,TwoS +116003242,116,[PIONEER T4.2a] Delayed Palliative Management_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +117003242,117,[PIONEER T4] PCa treated after conservative management ,324,without [PIONEER S24] Charlson CCI=0,TwoS +118003242,118,[PIONEER T4a] PCa treated after conservative management_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +119003242,119,[PIONEER T5] Symptom post conservative management ,324,without [PIONEER S24] Charlson CCI=0,TwoS +120003242,120,[PIONEER T5a] Symptom post conservative management_broad,324,without [PIONEER S24] Charlson CCI=0,TwoS +101003252,101,[PIONEER T1] Newly diagnosed Pca ,325,without [PIONEER S25] Charlson CCI=1,TwoS +102003252,102,[PIONEER T1a] Newly diagnosed Pca_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +103003252,103,[PIONEER T2] PCa treated right away,325,without [PIONEER S25] Charlson CCI=1,TwoS +104003252,104,[PIONEER T2a] PCa treated right away_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +105003252,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,325,without [PIONEER S25] Charlson CCI=1,TwoS +106003252,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +107003252,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,325,without [PIONEER S25] Charlson CCI=1,TwoS +108003252,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +109003252,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,325,without [PIONEER S25] Charlson CCI=1,TwoS +110003252,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +111003252,111,[PIONEER T3] PCa under conservative management,325,without [PIONEER S25] Charlson CCI=1,TwoS +112003252,112,[PIONEER T3a] PCa under conservative management_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +113003252,113,[PIONEER T4.1] Delayed Curative Management,325,without [PIONEER S25] Charlson CCI=1,TwoS +114003252,114,[PIONEER T4.1a] Delayed Curative Management_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +115003252,115,[PIONEER T4.2] Delayed Palliative Management,325,without [PIONEER S25] Charlson CCI=1,TwoS +116003252,116,[PIONEER T4.2a] Delayed Palliative Management_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +117003252,117,[PIONEER T4] PCa treated after conservative management ,325,without [PIONEER S25] Charlson CCI=1,TwoS +118003252,118,[PIONEER T4a] PCa treated after conservative management_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +119003252,119,[PIONEER T5] Symptom post conservative management ,325,without [PIONEER S25] Charlson CCI=1,TwoS +120003252,120,[PIONEER T5a] Symptom post conservative management_broad,325,without [PIONEER S25] Charlson CCI=1,TwoS +101003262,101,[PIONEER T1] Newly diagnosed Pca ,326,without [PIONEER S26] Charlson CCI>=2,TwoS +102003262,102,[PIONEER T1a] Newly diagnosed Pca_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +103003262,103,[PIONEER T2] PCa treated right away,326,without [PIONEER S26] Charlson CCI>=2,TwoS +104003262,104,[PIONEER T2a] PCa treated right away_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +105003262,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,326,without [PIONEER S26] Charlson CCI>=2,TwoS +106003262,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +107003262,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,326,without [PIONEER S26] Charlson CCI>=2,TwoS +108003262,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +109003262,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,326,without [PIONEER S26] Charlson CCI>=2,TwoS +110003262,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +111003262,111,[PIONEER T3] PCa under conservative management,326,without [PIONEER S26] Charlson CCI>=2,TwoS +112003262,112,[PIONEER T3a] PCa under conservative management_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +113003262,113,[PIONEER T4.1] Delayed Curative Management,326,without [PIONEER S26] Charlson CCI>=2,TwoS +114003262,114,[PIONEER T4.1a] Delayed Curative Management_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +115003262,115,[PIONEER T4.2] Delayed Palliative Management,326,without [PIONEER S26] Charlson CCI>=2,TwoS +116003262,116,[PIONEER T4.2a] Delayed Palliative Management_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +117003262,117,[PIONEER T4] PCa treated after conservative management ,326,without [PIONEER S26] Charlson CCI>=2,TwoS +118003262,118,[PIONEER T4a] PCa treated after conservative management_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +119003262,119,[PIONEER T5] Symptom post conservative management ,326,without [PIONEER S26] Charlson CCI>=2,TwoS +120003262,120,[PIONEER T5a] Symptom post conservative management_broad,326,without [PIONEER S26] Charlson CCI>=2,TwoS +101003272,101,[PIONEER T1] Newly diagnosed Pca ,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +102003272,102,[PIONEER T1a] Newly diagnosed Pca_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +103003272,103,[PIONEER T2] PCa treated right away,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +104003272,104,[PIONEER T2a] PCa treated right away_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +105003272,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +106003272,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +107003272,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +108003272,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +109003272,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +110003272,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +111003272,111,[PIONEER T3] PCa under conservative management,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +112003272,112,[PIONEER T3a] PCa under conservative management_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +113003272,113,[PIONEER T4.1] Delayed Curative Management,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +114003272,114,[PIONEER T4.1a] Delayed Curative Management_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +115003272,115,[PIONEER T4.2] Delayed Palliative Management,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +116003272,116,[PIONEER T4.2a] Delayed Palliative Management_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +117003272,117,[PIONEER T4] PCa treated after conservative management ,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +118003272,118,[PIONEER T4a] PCa treated after conservative management_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +119003272,119,[PIONEER T5] Symptom post conservative management ,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +120003272,120,[PIONEER T5a] Symptom post conservative management_broad,327,"without [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwoS +101003282,101,[PIONEER T1] Newly diagnosed Pca ,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +102003282,102,[PIONEER T1a] Newly diagnosed Pca_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +103003282,103,[PIONEER T2] PCa treated right away,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +104003282,104,[PIONEER T2a] PCa treated right away_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +105003282,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +106003282,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +107003282,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +108003282,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +109003282,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +110003282,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +111003282,111,[PIONEER T3] PCa under conservative management,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +112003282,112,[PIONEER T3a] PCa under conservative management_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +113003282,113,[PIONEER T4.1] Delayed Curative Management,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +114003282,114,[PIONEER T4.1a] Delayed Curative Management_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +115003282,115,[PIONEER T4.2] Delayed Palliative Management,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +116003282,116,[PIONEER T4.2a] Delayed Palliative Management_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +117003282,117,[PIONEER T4] PCa treated after conservative management ,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +118003282,118,[PIONEER T4a] PCa treated after conservative management_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +119003282,119,[PIONEER T5] Symptom post conservative management ,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +120003282,120,[PIONEER T5a] Symptom post conservative management_broad,328,without [PIONEER S31] Total Cardiovascular Disease Event,TwoS +101003292,101,[PIONEER T1] Newly diagnosed Pca ,329,without [PIONEER S32] Stroke,TwoS +102003292,102,[PIONEER T1a] Newly diagnosed Pca_broad,329,without [PIONEER S32] Stroke,TwoS +103003292,103,[PIONEER T2] PCa treated right away,329,without [PIONEER S32] Stroke,TwoS +104003292,104,[PIONEER T2a] PCa treated right away_broad,329,without [PIONEER S32] Stroke,TwoS +105003292,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,329,without [PIONEER S32] Stroke,TwoS +106003292,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,329,without [PIONEER S32] Stroke,TwoS +107003292,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,329,without [PIONEER S32] Stroke,TwoS +108003292,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,329,without [PIONEER S32] Stroke,TwoS +109003292,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,329,without [PIONEER S32] Stroke,TwoS +110003292,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,329,without [PIONEER S32] Stroke,TwoS +111003292,111,[PIONEER T3] PCa under conservative management,329,without [PIONEER S32] Stroke,TwoS +112003292,112,[PIONEER T3a] PCa under conservative management_broad,329,without [PIONEER S32] Stroke,TwoS +113003292,113,[PIONEER T4.1] Delayed Curative Management,329,without [PIONEER S32] Stroke,TwoS +114003292,114,[PIONEER T4.1a] Delayed Curative Management_broad,329,without [PIONEER S32] Stroke,TwoS +115003292,115,[PIONEER T4.2] Delayed Palliative Management,329,without [PIONEER S32] Stroke,TwoS +116003292,116,[PIONEER T4.2a] Delayed Palliative Management_broad,329,without [PIONEER S32] Stroke,TwoS +117003292,117,[PIONEER T4] PCa treated after conservative management ,329,without [PIONEER S32] Stroke,TwoS +118003292,118,[PIONEER T4a] PCa treated after conservative management_broad,329,without [PIONEER S32] Stroke,TwoS +119003292,119,[PIONEER T5] Symptom post conservative management ,329,without [PIONEER S32] Stroke,TwoS +120003292,120,[PIONEER T5a] Symptom post conservative management_broad,329,without [PIONEER S32] Stroke,TwoS +101003302,101,[PIONEER T1] Newly diagnosed Pca ,330,without [PIONEER S33] Type 2 Diabetes,TwoS +102003302,102,[PIONEER T1a] Newly diagnosed Pca_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +103003302,103,[PIONEER T2] PCa treated right away,330,without [PIONEER S33] Type 2 Diabetes,TwoS +104003302,104,[PIONEER T2a] PCa treated right away_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +105003302,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,330,without [PIONEER S33] Type 2 Diabetes,TwoS +106003302,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +107003302,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,330,without [PIONEER S33] Type 2 Diabetes,TwoS +108003302,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +109003302,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,330,without [PIONEER S33] Type 2 Diabetes,TwoS +110003302,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +111003302,111,[PIONEER T3] PCa under conservative management,330,without [PIONEER S33] Type 2 Diabetes,TwoS +112003302,112,[PIONEER T3a] PCa under conservative management_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +113003302,113,[PIONEER T4.1] Delayed Curative Management,330,without [PIONEER S33] Type 2 Diabetes,TwoS +114003302,114,[PIONEER T4.1a] Delayed Curative Management_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +115003302,115,[PIONEER T4.2] Delayed Palliative Management,330,without [PIONEER S33] Type 2 Diabetes,TwoS +116003302,116,[PIONEER T4.2a] Delayed Palliative Management_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +117003302,117,[PIONEER T4] PCa treated after conservative management ,330,without [PIONEER S33] Type 2 Diabetes,TwoS +118003302,118,[PIONEER T4a] PCa treated after conservative management_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +119003302,119,[PIONEER T5] Symptom post conservative management ,330,without [PIONEER S33] Type 2 Diabetes,TwoS +120003302,120,[PIONEER T5a] Symptom post conservative management_broad,330,without [PIONEER S33] Type 2 Diabetes,TwoS +101003312,101,[PIONEER T1] Newly diagnosed Pca ,331,without [PIONEER S34] Hypertension,TwoS +102003312,102,[PIONEER T1a] Newly diagnosed Pca_broad,331,without [PIONEER S34] Hypertension,TwoS +103003312,103,[PIONEER T2] PCa treated right away,331,without [PIONEER S34] Hypertension,TwoS +104003312,104,[PIONEER T2a] PCa treated right away_broad,331,without [PIONEER S34] Hypertension,TwoS +105003312,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,331,without [PIONEER S34] Hypertension,TwoS +106003312,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,331,without [PIONEER S34] Hypertension,TwoS +107003312,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,331,without [PIONEER S34] Hypertension,TwoS +108003312,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,331,without [PIONEER S34] Hypertension,TwoS +109003312,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,331,without [PIONEER S34] Hypertension,TwoS +110003312,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,331,without [PIONEER S34] Hypertension,TwoS +111003312,111,[PIONEER T3] PCa under conservative management,331,without [PIONEER S34] Hypertension,TwoS +112003312,112,[PIONEER T3a] PCa under conservative management_broad,331,without [PIONEER S34] Hypertension,TwoS +113003312,113,[PIONEER T4.1] Delayed Curative Management,331,without [PIONEER S34] Hypertension,TwoS +114003312,114,[PIONEER T4.1a] Delayed Curative Management_broad,331,without [PIONEER S34] Hypertension,TwoS +115003312,115,[PIONEER T4.2] Delayed Palliative Management,331,without [PIONEER S34] Hypertension,TwoS +116003312,116,[PIONEER T4.2a] Delayed Palliative Management_broad,331,without [PIONEER S34] Hypertension,TwoS +117003312,117,[PIONEER T4] PCa treated after conservative management ,331,without [PIONEER S34] Hypertension,TwoS +118003312,118,[PIONEER T4a] PCa treated after conservative management_broad,331,without [PIONEER S34] Hypertension,TwoS +119003312,119,[PIONEER T5] Symptom post conservative management ,331,without [PIONEER S34] Hypertension,TwoS +120003312,120,[PIONEER T5a] Symptom post conservative management_broad,331,without [PIONEER S34] Hypertension,TwoS +101003322,101,[PIONEER T1] Newly diagnosed Pca ,332,without [PIONEER S35] Obesity,TwoS +102003322,102,[PIONEER T1a] Newly diagnosed Pca_broad,332,without [PIONEER S35] Obesity,TwoS +103003322,103,[PIONEER T2] PCa treated right away,332,without [PIONEER S35] Obesity,TwoS +104003322,104,[PIONEER T2a] PCa treated right away_broad,332,without [PIONEER S35] Obesity,TwoS +105003322,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,332,without [PIONEER S35] Obesity,TwoS +106003322,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,332,without [PIONEER S35] Obesity,TwoS +107003322,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,332,without [PIONEER S35] Obesity,TwoS +108003322,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,332,without [PIONEER S35] Obesity,TwoS +109003322,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,332,without [PIONEER S35] Obesity,TwoS +110003322,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,332,without [PIONEER S35] Obesity,TwoS +111003322,111,[PIONEER T3] PCa under conservative management,332,without [PIONEER S35] Obesity,TwoS +112003322,112,[PIONEER T3a] PCa under conservative management_broad,332,without [PIONEER S35] Obesity,TwoS +113003322,113,[PIONEER T4.1] Delayed Curative Management,332,without [PIONEER S35] Obesity,TwoS +114003322,114,[PIONEER T4.1a] Delayed Curative Management_broad,332,without [PIONEER S35] Obesity,TwoS +115003322,115,[PIONEER T4.2] Delayed Palliative Management,332,without [PIONEER S35] Obesity,TwoS +116003322,116,[PIONEER T4.2a] Delayed Palliative Management_broad,332,without [PIONEER S35] Obesity,TwoS +117003322,117,[PIONEER T4] PCa treated after conservative management ,332,without [PIONEER S35] Obesity,TwoS +118003322,118,[PIONEER T4a] PCa treated after conservative management_broad,332,without [PIONEER S35] Obesity,TwoS +119003322,119,[PIONEER T5] Symptom post conservative management ,332,without [PIONEER S35] Obesity,TwoS +120003322,120,[PIONEER T5a] Symptom post conservative management_broad,332,without [PIONEER S35] Obesity,TwoS +101003332,101,[PIONEER T1] Newly diagnosed Pca ,333,without [PIONEER S36] VTE,TwoS +102003332,102,[PIONEER T1a] Newly diagnosed Pca_broad,333,without [PIONEER S36] VTE,TwoS +103003332,103,[PIONEER T2] PCa treated right away,333,without [PIONEER S36] VTE,TwoS +104003332,104,[PIONEER T2a] PCa treated right away_broad,333,without [PIONEER S36] VTE,TwoS +105003332,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,333,without [PIONEER S36] VTE,TwoS +106003332,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,333,without [PIONEER S36] VTE,TwoS +107003332,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,333,without [PIONEER S36] VTE,TwoS +108003332,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,333,without [PIONEER S36] VTE,TwoS +109003332,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,333,without [PIONEER S36] VTE,TwoS +110003332,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,333,without [PIONEER S36] VTE,TwoS +111003332,111,[PIONEER T3] PCa under conservative management,333,without [PIONEER S36] VTE,TwoS +112003332,112,[PIONEER T3a] PCa under conservative management_broad,333,without [PIONEER S36] VTE,TwoS +113003332,113,[PIONEER T4.1] Delayed Curative Management,333,without [PIONEER S36] VTE,TwoS +114003332,114,[PIONEER T4.1a] Delayed Curative Management_broad,333,without [PIONEER S36] VTE,TwoS +115003332,115,[PIONEER T4.2] Delayed Palliative Management,333,without [PIONEER S36] VTE,TwoS +116003332,116,[PIONEER T4.2a] Delayed Palliative Management_broad,333,without [PIONEER S36] VTE,TwoS +117003332,117,[PIONEER T4] PCa treated after conservative management ,333,without [PIONEER S36] VTE,TwoS +118003332,118,[PIONEER T4a] PCa treated after conservative management_broad,333,without [PIONEER S36] VTE,TwoS +119003332,119,[PIONEER T5] Symptom post conservative management ,333,without [PIONEER S36] VTE,TwoS +120003332,120,[PIONEER T5a] Symptom post conservative management_broad,333,without [PIONEER S36] VTE,TwoS +101003342,101,[PIONEER T1] Newly diagnosed Pca ,334,without [PIONEER S28] Performance status ECOG=0,TwoS +102003342,102,[PIONEER T1a] Newly diagnosed Pca_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +103003342,103,[PIONEER T2] PCa treated right away,334,without [PIONEER S28] Performance status ECOG=0,TwoS +104003342,104,[PIONEER T2a] PCa treated right away_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +105003342,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,334,without [PIONEER S28] Performance status ECOG=0,TwoS +106003342,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +107003342,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,334,without [PIONEER S28] Performance status ECOG=0,TwoS +108003342,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +109003342,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,334,without [PIONEER S28] Performance status ECOG=0,TwoS +110003342,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +111003342,111,[PIONEER T3] PCa under conservative management,334,without [PIONEER S28] Performance status ECOG=0,TwoS +112003342,112,[PIONEER T3a] PCa under conservative management_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +113003342,113,[PIONEER T4.1] Delayed Curative Management,334,without [PIONEER S28] Performance status ECOG=0,TwoS +114003342,114,[PIONEER T4.1a] Delayed Curative Management_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +115003342,115,[PIONEER T4.2] Delayed Palliative Management,334,without [PIONEER S28] Performance status ECOG=0,TwoS +116003342,116,[PIONEER T4.2a] Delayed Palliative Management_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +117003342,117,[PIONEER T4] PCa treated after conservative management ,334,without [PIONEER S28] Performance status ECOG=0,TwoS +118003342,118,[PIONEER T4a] PCa treated after conservative management_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +119003342,119,[PIONEER T5] Symptom post conservative management ,334,without [PIONEER S28] Performance status ECOG=0,TwoS +120003342,120,[PIONEER T5a] Symptom post conservative management_broad,334,without [PIONEER S28] Performance status ECOG=0,TwoS +101003352,101,[PIONEER T1] Newly diagnosed Pca ,335,without [PIONEER S29] Performance status ECOG=1,TwoS +102003352,102,[PIONEER T1a] Newly diagnosed Pca_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +103003352,103,[PIONEER T2] PCa treated right away,335,without [PIONEER S29] Performance status ECOG=1,TwoS +104003352,104,[PIONEER T2a] PCa treated right away_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +105003352,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,335,without [PIONEER S29] Performance status ECOG=1,TwoS +106003352,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +107003352,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,335,without [PIONEER S29] Performance status ECOG=1,TwoS +108003352,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +109003352,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,335,without [PIONEER S29] Performance status ECOG=1,TwoS +110003352,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +111003352,111,[PIONEER T3] PCa under conservative management,335,without [PIONEER S29] Performance status ECOG=1,TwoS +112003352,112,[PIONEER T3a] PCa under conservative management_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +113003352,113,[PIONEER T4.1] Delayed Curative Management,335,without [PIONEER S29] Performance status ECOG=1,TwoS +114003352,114,[PIONEER T4.1a] Delayed Curative Management_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +115003352,115,[PIONEER T4.2] Delayed Palliative Management,335,without [PIONEER S29] Performance status ECOG=1,TwoS +116003352,116,[PIONEER T4.2a] Delayed Palliative Management_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +117003352,117,[PIONEER T4] PCa treated after conservative management ,335,without [PIONEER S29] Performance status ECOG=1,TwoS +118003352,118,[PIONEER T4a] PCa treated after conservative management_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +119003352,119,[PIONEER T5] Symptom post conservative management ,335,without [PIONEER S29] Performance status ECOG=1,TwoS +120003352,120,[PIONEER T5a] Symptom post conservative management_broad,335,without [PIONEER S29] Performance status ECOG=1,TwoS +101003362,101,[PIONEER T1] Newly diagnosed Pca ,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +102003362,102,[PIONEER T1a] Newly diagnosed Pca_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +103003362,103,[PIONEER T2] PCa treated right away,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +104003362,104,[PIONEER T2a] PCa treated right away_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +105003362,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +106003362,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +107003362,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +108003362,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +109003362,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +110003362,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +111003362,111,[PIONEER T3] PCa under conservative management,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +112003362,112,[PIONEER T3a] PCa under conservative management_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +113003362,113,[PIONEER T4.1] Delayed Curative Management,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +114003362,114,[PIONEER T4.1a] Delayed Curative Management_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +115003362,115,[PIONEER T4.2] Delayed Palliative Management,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +116003362,116,[PIONEER T4.2a] Delayed Palliative Management_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +117003362,117,[PIONEER T4] PCa treated after conservative management ,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +118003362,118,[PIONEER T4a] PCa treated after conservative management_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +119003362,119,[PIONEER T5] Symptom post conservative management ,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +120003362,120,[PIONEER T5a] Symptom post conservative management_broad,336,without [PIONEER S30] Performance status ECOG=2+,TwoS +101003372,101,[PIONEER T1] Newly diagnosed Pca ,337,without [PIONEER S37] Anxiety,TwoS +102003372,102,[PIONEER T1a] Newly diagnosed Pca_broad,337,without [PIONEER S37] Anxiety,TwoS +103003372,103,[PIONEER T2] PCa treated right away,337,without [PIONEER S37] Anxiety,TwoS +104003372,104,[PIONEER T2a] PCa treated right away_broad,337,without [PIONEER S37] Anxiety,TwoS +105003372,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,337,without [PIONEER S37] Anxiety,TwoS +106003372,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,337,without [PIONEER S37] Anxiety,TwoS +107003372,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,337,without [PIONEER S37] Anxiety,TwoS +108003372,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,337,without [PIONEER S37] Anxiety,TwoS +109003372,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,337,without [PIONEER S37] Anxiety,TwoS +110003372,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,337,without [PIONEER S37] Anxiety,TwoS +111003372,111,[PIONEER T3] PCa under conservative management,337,without [PIONEER S37] Anxiety,TwoS +112003372,112,[PIONEER T3a] PCa under conservative management_broad,337,without [PIONEER S37] Anxiety,TwoS +113003372,113,[PIONEER T4.1] Delayed Curative Management,337,without [PIONEER S37] Anxiety,TwoS +114003372,114,[PIONEER T4.1a] Delayed Curative Management_broad,337,without [PIONEER S37] Anxiety,TwoS +115003372,115,[PIONEER T4.2] Delayed Palliative Management,337,without [PIONEER S37] Anxiety,TwoS +116003372,116,[PIONEER T4.2a] Delayed Palliative Management_broad,337,without [PIONEER S37] Anxiety,TwoS +117003372,117,[PIONEER T4] PCa treated after conservative management ,337,without [PIONEER S37] Anxiety,TwoS +118003372,118,[PIONEER T4a] PCa treated after conservative management_broad,337,without [PIONEER S37] Anxiety,TwoS +119003372,119,[PIONEER T5] Symptom post conservative management ,337,without [PIONEER S37] Anxiety,TwoS +120003372,120,[PIONEER T5a] Symptom post conservative management_broad,337,without [PIONEER S37] Anxiety,TwoS +101003382,101,[PIONEER T1] Newly diagnosed Pca ,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +102003382,102,[PIONEER T1a] Newly diagnosed Pca_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +103003382,103,[PIONEER T2] PCa treated right away,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +104003382,104,[PIONEER T2a] PCa treated right away_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +105003382,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +106003382,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +107003382,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +108003382,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +109003382,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +110003382,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +111003382,111,[PIONEER T3] PCa under conservative management,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +112003382,112,[PIONEER T3a] PCa under conservative management_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +113003382,113,[PIONEER T4.1] Delayed Curative Management,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +114003382,114,[PIONEER T4.1a] Delayed Curative Management_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +115003382,115,[PIONEER T4.2] Delayed Palliative Management,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +116003382,116,[PIONEER T4.2a] Delayed Palliative Management_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +117003382,117,[PIONEER T4] PCa treated after conservative management ,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +118003382,118,[PIONEER T4a] PCa treated after conservative management_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +119003382,119,[PIONEER T5] Symptom post conservative management ,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +120003382,120,[PIONEER T5a] Symptom post conservative management_broad,338,without [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwoS +101000011,101,[PIONEER T1] Newly diagnosed Pca ,1,with Full 365-day follow up,TwS +102000011,102,[PIONEER T1a] Newly diagnosed Pca_broad,1,with Full 365-day follow up,TwS +103000011,103,[PIONEER T2] PCa treated right away,1,with Full 365-day follow up,TwS +104000011,104,[PIONEER T2a] PCa treated right away_broad,1,with Full 365-day follow up,TwS +105000011,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,1,with Full 365-day follow up,TwS +106000011,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,1,with Full 365-day follow up,TwS +107000011,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,1,with Full 365-day follow up,TwS +108000011,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,1,with Full 365-day follow up,TwS +109000011,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,1,with Full 365-day follow up,TwS +110000011,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,1,with Full 365-day follow up,TwS +111000011,111,[PIONEER T3] PCa under conservative management,1,with Full 365-day follow up,TwS +112000011,112,[PIONEER T3a] PCa under conservative management_broad,1,with Full 365-day follow up,TwS +113000011,113,[PIONEER T4.1] Delayed Curative Management,1,with Full 365-day follow up,TwS +114000011,114,[PIONEER T4.1a] Delayed Curative Management_broad,1,with Full 365-day follow up,TwS +115000011,115,[PIONEER T4.2] Delayed Palliative Management,1,with Full 365-day follow up,TwS +116000011,116,[PIONEER T4.2a] Delayed Palliative Management_broad,1,with Full 365-day follow up,TwS +117000011,117,[PIONEER T4] PCa treated after conservative management ,1,with Full 365-day follow up,TwS +118000011,118,[PIONEER T4a] PCa treated after conservative management_broad,1,with Full 365-day follow up,TwS +119000011,119,[PIONEER T5] Symptom post conservative management ,1,with Full 365-day follow up,TwS +120000011,120,[PIONEER T5a] Symptom post conservative management_broad,1,with Full 365-day follow up,TwS +101000021,101,[PIONEER T1] Newly diagnosed Pca ,2,with < 365-day follow up,TwS +102000021,102,[PIONEER T1a] Newly diagnosed Pca_broad,2,with < 365-day follow up,TwS +103000021,103,[PIONEER T2] PCa treated right away,2,with < 365-day follow up,TwS +104000021,104,[PIONEER T2a] PCa treated right away_broad,2,with < 365-day follow up,TwS +105000021,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,2,with < 365-day follow up,TwS +106000021,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,2,with < 365-day follow up,TwS +107000021,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,2,with < 365-day follow up,TwS +108000021,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,2,with < 365-day follow up,TwS +109000021,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,2,with < 365-day follow up,TwS +110000021,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,2,with < 365-day follow up,TwS +111000021,111,[PIONEER T3] PCa under conservative management,2,with < 365-day follow up,TwS +112000021,112,[PIONEER T3a] PCa under conservative management_broad,2,with < 365-day follow up,TwS +113000021,113,[PIONEER T4.1] Delayed Curative Management,2,with < 365-day follow up,TwS +114000021,114,[PIONEER T4.1a] Delayed Curative Management_broad,2,with < 365-day follow up,TwS +115000021,115,[PIONEER T4.2] Delayed Palliative Management,2,with < 365-day follow up,TwS +116000021,116,[PIONEER T4.2a] Delayed Palliative Management_broad,2,with < 365-day follow up,TwS +117000021,117,[PIONEER T4] PCa treated after conservative management ,2,with < 365-day follow up,TwS +118000021,118,[PIONEER T4a] PCa treated after conservative management_broad,2,with < 365-day follow up,TwS +119000021,119,[PIONEER T5] Symptom post conservative management ,2,with < 365-day follow up,TwS +120000021,120,[PIONEER T5a] Symptom post conservative management_broad,2,with < 365-day follow up,TwS +101000061,101,[PIONEER T1] Newly diagnosed Pca ,6,with Black or African American,TwS +102000061,102,[PIONEER T1a] Newly diagnosed Pca_broad,6,with Black or African American,TwS +103000061,103,[PIONEER T2] PCa treated right away,6,with Black or African American,TwS +104000061,104,[PIONEER T2a] PCa treated right away_broad,6,with Black or African American,TwS +105000061,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,6,with Black or African American,TwS +106000061,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,6,with Black or African American,TwS +107000061,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,6,with Black or African American,TwS +108000061,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,6,with Black or African American,TwS +109000061,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,6,with Black or African American,TwS +110000061,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,6,with Black or African American,TwS +111000061,111,[PIONEER T3] PCa under conservative management,6,with Black or African American,TwS +112000061,112,[PIONEER T3a] PCa under conservative management_broad,6,with Black or African American,TwS +113000061,113,[PIONEER T4.1] Delayed Curative Management,6,with Black or African American,TwS +114000061,114,[PIONEER T4.1a] Delayed Curative Management_broad,6,with Black or African American,TwS +115000061,115,[PIONEER T4.2] Delayed Palliative Management,6,with Black or African American,TwS +116000061,116,[PIONEER T4.2a] Delayed Palliative Management_broad,6,with Black or African American,TwS +117000061,117,[PIONEER T4] PCa treated after conservative management ,6,with Black or African American,TwS +118000061,118,[PIONEER T4a] PCa treated after conservative management_broad,6,with Black or African American,TwS +119000061,119,[PIONEER T5] Symptom post conservative management ,6,with Black or African American,TwS +120000061,120,[PIONEER T5a] Symptom post conservative management_broad,6,with Black or African American,TwS +101000071,101,[PIONEER T1] Newly diagnosed Pca ,7,with White,TwS +102000071,102,[PIONEER T1a] Newly diagnosed Pca_broad,7,with White,TwS +103000071,103,[PIONEER T2] PCa treated right away,7,with White,TwS +104000071,104,[PIONEER T2a] PCa treated right away_broad,7,with White,TwS +105000071,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,7,with White,TwS +106000071,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,7,with White,TwS +107000071,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,7,with White,TwS +108000071,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,7,with White,TwS +109000071,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,7,with White,TwS +110000071,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,7,with White,TwS +111000071,111,[PIONEER T3] PCa under conservative management,7,with White,TwS +112000071,112,[PIONEER T3a] PCa under conservative management_broad,7,with White,TwS +113000071,113,[PIONEER T4.1] Delayed Curative Management,7,with White,TwS +114000071,114,[PIONEER T4.1a] Delayed Curative Management_broad,7,with White,TwS +115000071,115,[PIONEER T4.2] Delayed Palliative Management,7,with White,TwS +116000071,116,[PIONEER T4.2a] Delayed Palliative Management_broad,7,with White,TwS +117000071,117,[PIONEER T4] PCa treated after conservative management ,7,with White,TwS +118000071,118,[PIONEER T4a] PCa treated after conservative management_broad,7,with White,TwS +119000071,119,[PIONEER T5] Symptom post conservative management ,7,with White,TwS +120000071,120,[PIONEER T5a] Symptom post conservative management_broad,7,with White,TwS +101003011,101,[PIONEER T1] Newly diagnosed Pca ,301,with [PIONEER S1] EAU High Risk,TwS +102003011,102,[PIONEER T1a] Newly diagnosed Pca_broad,301,with [PIONEER S1] EAU High Risk,TwS +103003011,103,[PIONEER T2] PCa treated right away,301,with [PIONEER S1] EAU High Risk,TwS +104003011,104,[PIONEER T2a] PCa treated right away_broad,301,with [PIONEER S1] EAU High Risk,TwS +105003011,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,301,with [PIONEER S1] EAU High Risk,TwS +106003011,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,301,with [PIONEER S1] EAU High Risk,TwS +107003011,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,301,with [PIONEER S1] EAU High Risk,TwS +108003011,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,301,with [PIONEER S1] EAU High Risk,TwS +109003011,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,301,with [PIONEER S1] EAU High Risk,TwS +110003011,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,301,with [PIONEER S1] EAU High Risk,TwS +111003011,111,[PIONEER T3] PCa under conservative management,301,with [PIONEER S1] EAU High Risk,TwS +112003011,112,[PIONEER T3a] PCa under conservative management_broad,301,with [PIONEER S1] EAU High Risk,TwS +113003011,113,[PIONEER T4.1] Delayed Curative Management,301,with [PIONEER S1] EAU High Risk,TwS +114003011,114,[PIONEER T4.1a] Delayed Curative Management_broad,301,with [PIONEER S1] EAU High Risk,TwS +115003011,115,[PIONEER T4.2] Delayed Palliative Management,301,with [PIONEER S1] EAU High Risk,TwS +116003011,116,[PIONEER T4.2a] Delayed Palliative Management_broad,301,with [PIONEER S1] EAU High Risk,TwS +117003011,117,[PIONEER T4] PCa treated after conservative management ,301,with [PIONEER S1] EAU High Risk,TwS +118003011,118,[PIONEER T4a] PCa treated after conservative management_broad,301,with [PIONEER S1] EAU High Risk,TwS +119003011,119,[PIONEER T5] Symptom post conservative management ,301,with [PIONEER S1] EAU High Risk,TwS +120003011,120,[PIONEER T5a] Symptom post conservative management_broad,301,with [PIONEER S1] EAU High Risk,TwS +101003021,101,[PIONEER T1] Newly diagnosed Pca ,302,with [PIONEER S2] EAU Low Risk,TwS +102003021,102,[PIONEER T1a] Newly diagnosed Pca_broad,302,with [PIONEER S2] EAU Low Risk,TwS +103003021,103,[PIONEER T2] PCa treated right away,302,with [PIONEER S2] EAU Low Risk,TwS +104003021,104,[PIONEER T2a] PCa treated right away_broad,302,with [PIONEER S2] EAU Low Risk,TwS +105003021,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,302,with [PIONEER S2] EAU Low Risk,TwS +106003021,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,302,with [PIONEER S2] EAU Low Risk,TwS +107003021,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,302,with [PIONEER S2] EAU Low Risk,TwS +108003021,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,302,with [PIONEER S2] EAU Low Risk,TwS +109003021,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,302,with [PIONEER S2] EAU Low Risk,TwS +110003021,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,302,with [PIONEER S2] EAU Low Risk,TwS +111003021,111,[PIONEER T3] PCa under conservative management,302,with [PIONEER S2] EAU Low Risk,TwS +112003021,112,[PIONEER T3a] PCa under conservative management_broad,302,with [PIONEER S2] EAU Low Risk,TwS +113003021,113,[PIONEER T4.1] Delayed Curative Management,302,with [PIONEER S2] EAU Low Risk,TwS +114003021,114,[PIONEER T4.1a] Delayed Curative Management_broad,302,with [PIONEER S2] EAU Low Risk,TwS +115003021,115,[PIONEER T4.2] Delayed Palliative Management,302,with [PIONEER S2] EAU Low Risk,TwS +116003021,116,[PIONEER T4.2a] Delayed Palliative Management_broad,302,with [PIONEER S2] EAU Low Risk,TwS +117003021,117,[PIONEER T4] PCa treated after conservative management ,302,with [PIONEER S2] EAU Low Risk,TwS +118003021,118,[PIONEER T4a] PCa treated after conservative management_broad,302,with [PIONEER S2] EAU Low Risk,TwS +119003021,119,[PIONEER T5] Symptom post conservative management ,302,with [PIONEER S2] EAU Low Risk,TwS +120003021,120,[PIONEER T5a] Symptom post conservative management_broad,302,with [PIONEER S2] EAU Low Risk,TwS +101003031,101,[PIONEER T1] Newly diagnosed Pca ,303,with [PIONEER S3] EAU Intermediate Risk,TwS +102003031,102,[PIONEER T1a] Newly diagnosed Pca_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +103003031,103,[PIONEER T2] PCa treated right away,303,with [PIONEER S3] EAU Intermediate Risk,TwS +104003031,104,[PIONEER T2a] PCa treated right away_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +105003031,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,303,with [PIONEER S3] EAU Intermediate Risk,TwS +106003031,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +107003031,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,303,with [PIONEER S3] EAU Intermediate Risk,TwS +108003031,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +109003031,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,303,with [PIONEER S3] EAU Intermediate Risk,TwS +110003031,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +111003031,111,[PIONEER T3] PCa under conservative management,303,with [PIONEER S3] EAU Intermediate Risk,TwS +112003031,112,[PIONEER T3a] PCa under conservative management_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +113003031,113,[PIONEER T4.1] Delayed Curative Management,303,with [PIONEER S3] EAU Intermediate Risk,TwS +114003031,114,[PIONEER T4.1a] Delayed Curative Management_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +115003031,115,[PIONEER T4.2] Delayed Palliative Management,303,with [PIONEER S3] EAU Intermediate Risk,TwS +116003031,116,[PIONEER T4.2a] Delayed Palliative Management_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +117003031,117,[PIONEER T4] PCa treated after conservative management ,303,with [PIONEER S3] EAU Intermediate Risk,TwS +118003031,118,[PIONEER T4a] PCa treated after conservative management_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +119003031,119,[PIONEER T5] Symptom post conservative management ,303,with [PIONEER S3] EAU Intermediate Risk,TwS +120003031,120,[PIONEER T5a] Symptom post conservative management_broad,303,with [PIONEER S3] EAU Intermediate Risk,TwS +101003041,101,[PIONEER T1] Newly diagnosed Pca ,304,with [PIONEER S4] Metastatic PCa,TwS +102003041,102,[PIONEER T1a] Newly diagnosed Pca_broad,304,with [PIONEER S4] Metastatic PCa,TwS +103003041,103,[PIONEER T2] PCa treated right away,304,with [PIONEER S4] Metastatic PCa,TwS +104003041,104,[PIONEER T2a] PCa treated right away_broad,304,with [PIONEER S4] Metastatic PCa,TwS +105003041,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,304,with [PIONEER S4] Metastatic PCa,TwS +106003041,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,304,with [PIONEER S4] Metastatic PCa,TwS +107003041,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,304,with [PIONEER S4] Metastatic PCa,TwS +108003041,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,304,with [PIONEER S4] Metastatic PCa,TwS +109003041,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,304,with [PIONEER S4] Metastatic PCa,TwS +110003041,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,304,with [PIONEER S4] Metastatic PCa,TwS +111003041,111,[PIONEER T3] PCa under conservative management,304,with [PIONEER S4] Metastatic PCa,TwS +112003041,112,[PIONEER T3a] PCa under conservative management_broad,304,with [PIONEER S4] Metastatic PCa,TwS +113003041,113,[PIONEER T4.1] Delayed Curative Management,304,with [PIONEER S4] Metastatic PCa,TwS +114003041,114,[PIONEER T4.1a] Delayed Curative Management_broad,304,with [PIONEER S4] Metastatic PCa,TwS +115003041,115,[PIONEER T4.2] Delayed Palliative Management,304,with [PIONEER S4] Metastatic PCa,TwS +116003041,116,[PIONEER T4.2a] Delayed Palliative Management_broad,304,with [PIONEER S4] Metastatic PCa,TwS +117003041,117,[PIONEER T4] PCa treated after conservative management ,304,with [PIONEER S4] Metastatic PCa,TwS +118003041,118,[PIONEER T4a] PCa treated after conservative management_broad,304,with [PIONEER S4] Metastatic PCa,TwS +119003041,119,[PIONEER T5] Symptom post conservative management ,304,with [PIONEER S4] Metastatic PCa,TwS +120003041,120,[PIONEER T5a] Symptom post conservative management_broad,304,with [PIONEER S4] Metastatic PCa,TwS +101003051,101,[PIONEER T1] Newly diagnosed Pca ,305,with [PIONEER S5] Locally Advanced PCa,TwS +102003051,102,[PIONEER T1a] Newly diagnosed Pca_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +103003051,103,[PIONEER T2] PCa treated right away,305,with [PIONEER S5] Locally Advanced PCa,TwS +104003051,104,[PIONEER T2a] PCa treated right away_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +105003051,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,305,with [PIONEER S5] Locally Advanced PCa,TwS +106003051,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +107003051,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,305,with [PIONEER S5] Locally Advanced PCa,TwS +108003051,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +109003051,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,305,with [PIONEER S5] Locally Advanced PCa,TwS +110003051,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +111003051,111,[PIONEER T3] PCa under conservative management,305,with [PIONEER S5] Locally Advanced PCa,TwS +112003051,112,[PIONEER T3a] PCa under conservative management_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +113003051,113,[PIONEER T4.1] Delayed Curative Management,305,with [PIONEER S5] Locally Advanced PCa,TwS +114003051,114,[PIONEER T4.1a] Delayed Curative Management_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +115003051,115,[PIONEER T4.2] Delayed Palliative Management,305,with [PIONEER S5] Locally Advanced PCa,TwS +116003051,116,[PIONEER T4.2a] Delayed Palliative Management_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +117003051,117,[PIONEER T4] PCa treated after conservative management ,305,with [PIONEER S5] Locally Advanced PCa,TwS +118003051,118,[PIONEER T4a] PCa treated after conservative management_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +119003051,119,[PIONEER T5] Symptom post conservative management ,305,with [PIONEER S5] Locally Advanced PCa,TwS +120003051,120,[PIONEER T5a] Symptom post conservative management_broad,305,with [PIONEER S5] Locally Advanced PCa,TwS +101003061,101,[PIONEER T1] Newly diagnosed Pca ,306,with [PIONEER S6] localized PCa,TwS +102003061,102,[PIONEER T1a] Newly diagnosed Pca_broad,306,with [PIONEER S6] localized PCa,TwS +103003061,103,[PIONEER T2] PCa treated right away,306,with [PIONEER S6] localized PCa,TwS +104003061,104,[PIONEER T2a] PCa treated right away_broad,306,with [PIONEER S6] localized PCa,TwS +105003061,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,306,with [PIONEER S6] localized PCa,TwS +106003061,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,306,with [PIONEER S6] localized PCa,TwS +107003061,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,306,with [PIONEER S6] localized PCa,TwS +108003061,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,306,with [PIONEER S6] localized PCa,TwS +109003061,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,306,with [PIONEER S6] localized PCa,TwS +110003061,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,306,with [PIONEER S6] localized PCa,TwS +111003061,111,[PIONEER T3] PCa under conservative management,306,with [PIONEER S6] localized PCa,TwS +112003061,112,[PIONEER T3a] PCa under conservative management_broad,306,with [PIONEER S6] localized PCa,TwS +113003061,113,[PIONEER T4.1] Delayed Curative Management,306,with [PIONEER S6] localized PCa,TwS +114003061,114,[PIONEER T4.1a] Delayed Curative Management_broad,306,with [PIONEER S6] localized PCa,TwS +115003061,115,[PIONEER T4.2] Delayed Palliative Management,306,with [PIONEER S6] localized PCa,TwS +116003061,116,[PIONEER T4.2a] Delayed Palliative Management_broad,306,with [PIONEER S6] localized PCa,TwS +117003061,117,[PIONEER T4] PCa treated after conservative management ,306,with [PIONEER S6] localized PCa,TwS +118003061,118,[PIONEER T4a] PCa treated after conservative management_broad,306,with [PIONEER S6] localized PCa,TwS +119003061,119,[PIONEER T5] Symptom post conservative management ,306,with [PIONEER S6] localized PCa,TwS +120003061,120,[PIONEER T5a] Symptom post conservative management_broad,306,with [PIONEER S6] localized PCa,TwS +101003071,101,[PIONEER T1] Newly diagnosed Pca ,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +102003071,102,[PIONEER T1a] Newly diagnosed Pca_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +103003071,103,[PIONEER T2] PCa treated right away,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +104003071,104,[PIONEER T2a] PCa treated right away_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +105003071,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +106003071,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +107003071,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +108003071,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +109003071,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +110003071,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +111003071,111,[PIONEER T3] PCa under conservative management,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +112003071,112,[PIONEER T3a] PCa under conservative management_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +113003071,113,[PIONEER T4.1] Delayed Curative Management,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +114003071,114,[PIONEER T4.1a] Delayed Curative Management_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +115003071,115,[PIONEER T4.2] Delayed Palliative Management,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +116003071,116,[PIONEER T4.2a] Delayed Palliative Management_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +117003071,117,[PIONEER T4] PCa treated after conservative management ,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +118003071,118,[PIONEER T4a] PCa treated after conservative management_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +119003071,119,[PIONEER T5] Symptom post conservative management ,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +120003071,120,[PIONEER T5a] Symptom post conservative management_broad,307,with [PIONEER S7] PSA >20 at Diagnosis,TwS +101003081,101,[PIONEER T1] Newly diagnosed Pca ,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +102003081,102,[PIONEER T1a] Newly diagnosed Pca_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +103003081,103,[PIONEER T2] PCa treated right away,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +104003081,104,[PIONEER T2a] PCa treated right away_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +105003081,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +106003081,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +107003081,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +108003081,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +109003081,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +110003081,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +111003081,111,[PIONEER T3] PCa under conservative management,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +112003081,112,[PIONEER T3a] PCa under conservative management_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +113003081,113,[PIONEER T4.1] Delayed Curative Management,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +114003081,114,[PIONEER T4.1a] Delayed Curative Management_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +115003081,115,[PIONEER T4.2] Delayed Palliative Management,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +116003081,116,[PIONEER T4.2a] Delayed Palliative Management_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +117003081,117,[PIONEER T4] PCa treated after conservative management ,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +118003081,118,[PIONEER T4a] PCa treated after conservative management_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +119003081,119,[PIONEER T5] Symptom post conservative management ,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +120003081,120,[PIONEER T5a] Symptom post conservative management_broad,308,with [PIONEER S8] PSA <10 at Diagnosis,TwS +101003091,101,[PIONEER T1] Newly diagnosed Pca ,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +102003091,102,[PIONEER T1a] Newly diagnosed Pca_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +103003091,103,[PIONEER T2] PCa treated right away,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +104003091,104,[PIONEER T2a] PCa treated right away_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +105003091,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +106003091,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +107003091,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +108003091,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +109003091,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +110003091,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +111003091,111,[PIONEER T3] PCa under conservative management,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +112003091,112,[PIONEER T3a] PCa under conservative management_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +113003091,113,[PIONEER T4.1] Delayed Curative Management,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +114003091,114,[PIONEER T4.1a] Delayed Curative Management_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +115003091,115,[PIONEER T4.2] Delayed Palliative Management,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +116003091,116,[PIONEER T4.2a] Delayed Palliative Management_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +117003091,117,[PIONEER T4] PCa treated after conservative management ,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +118003091,118,[PIONEER T4a] PCa treated after conservative management_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +119003091,119,[PIONEER T5] Symptom post conservative management ,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +120003091,120,[PIONEER T5a] Symptom post conservative management_broad,309,with [PIONEER S9] PSA 10-20 at Diagnosis,TwS +101003101,101,[PIONEER T1] Newly diagnosed Pca ,310,with [PIONEER S10] Stage cT1 at Dx,TwS +102003101,102,[PIONEER T1a] Newly diagnosed Pca_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +103003101,103,[PIONEER T2] PCa treated right away,310,with [PIONEER S10] Stage cT1 at Dx,TwS +104003101,104,[PIONEER T2a] PCa treated right away_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +105003101,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,310,with [PIONEER S10] Stage cT1 at Dx,TwS +106003101,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +107003101,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,310,with [PIONEER S10] Stage cT1 at Dx,TwS +108003101,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +109003101,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,310,with [PIONEER S10] Stage cT1 at Dx,TwS +110003101,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +111003101,111,[PIONEER T3] PCa under conservative management,310,with [PIONEER S10] Stage cT1 at Dx,TwS +112003101,112,[PIONEER T3a] PCa under conservative management_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +113003101,113,[PIONEER T4.1] Delayed Curative Management,310,with [PIONEER S10] Stage cT1 at Dx,TwS +114003101,114,[PIONEER T4.1a] Delayed Curative Management_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +115003101,115,[PIONEER T4.2] Delayed Palliative Management,310,with [PIONEER S10] Stage cT1 at Dx,TwS +116003101,116,[PIONEER T4.2a] Delayed Palliative Management_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +117003101,117,[PIONEER T4] PCa treated after conservative management ,310,with [PIONEER S10] Stage cT1 at Dx,TwS +118003101,118,[PIONEER T4a] PCa treated after conservative management_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +119003101,119,[PIONEER T5] Symptom post conservative management ,310,with [PIONEER S10] Stage cT1 at Dx,TwS +120003101,120,[PIONEER T5a] Symptom post conservative management_broad,310,with [PIONEER S10] Stage cT1 at Dx,TwS +101003111,101,[PIONEER T1] Newly diagnosed Pca ,311,with [PIONEER S11] Stage cT2 at Dx,TwS +102003111,102,[PIONEER T1a] Newly diagnosed Pca_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +103003111,103,[PIONEER T2] PCa treated right away,311,with [PIONEER S11] Stage cT2 at Dx,TwS +104003111,104,[PIONEER T2a] PCa treated right away_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +105003111,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,311,with [PIONEER S11] Stage cT2 at Dx,TwS +106003111,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +107003111,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,311,with [PIONEER S11] Stage cT2 at Dx,TwS +108003111,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +109003111,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,311,with [PIONEER S11] Stage cT2 at Dx,TwS +110003111,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +111003111,111,[PIONEER T3] PCa under conservative management,311,with [PIONEER S11] Stage cT2 at Dx,TwS +112003111,112,[PIONEER T3a] PCa under conservative management_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +113003111,113,[PIONEER T4.1] Delayed Curative Management,311,with [PIONEER S11] Stage cT2 at Dx,TwS +114003111,114,[PIONEER T4.1a] Delayed Curative Management_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +115003111,115,[PIONEER T4.2] Delayed Palliative Management,311,with [PIONEER S11] Stage cT2 at Dx,TwS +116003111,116,[PIONEER T4.2a] Delayed Palliative Management_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +117003111,117,[PIONEER T4] PCa treated after conservative management ,311,with [PIONEER S11] Stage cT2 at Dx,TwS +118003111,118,[PIONEER T4a] PCa treated after conservative management_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +119003111,119,[PIONEER T5] Symptom post conservative management ,311,with [PIONEER S11] Stage cT2 at Dx,TwS +120003111,120,[PIONEER T5a] Symptom post conservative management_broad,311,with [PIONEER S11] Stage cT2 at Dx,TwS +101003121,101,[PIONEER T1] Newly diagnosed Pca ,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +102003121,102,[PIONEER T1a] Newly diagnosed Pca_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +103003121,103,[PIONEER T2] PCa treated right away,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +104003121,104,[PIONEER T2a] PCa treated right away_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +105003121,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +106003121,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +107003121,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +108003121,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +109003121,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +110003121,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +111003121,111,[PIONEER T3] PCa under conservative management,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +112003121,112,[PIONEER T3a] PCa under conservative management_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +113003121,113,[PIONEER T4.1] Delayed Curative Management,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +114003121,114,[PIONEER T4.1a] Delayed Curative Management_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +115003121,115,[PIONEER T4.2] Delayed Palliative Management,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +116003121,116,[PIONEER T4.2a] Delayed Palliative Management_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +117003121,117,[PIONEER T4] PCa treated after conservative management ,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +118003121,118,[PIONEER T4a] PCa treated after conservative management_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +119003121,119,[PIONEER T5] Symptom post conservative management ,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +120003121,120,[PIONEER T5a] Symptom post conservative management_broad,312,with [PIONEER S12] Stage cT3/cT4 at Dx,TwS +101003131,101,[PIONEER T1] Newly diagnosed Pca ,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +102003131,102,[PIONEER T1a] Newly diagnosed Pca_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +103003131,103,[PIONEER T2] PCa treated right away,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +104003131,104,[PIONEER T2a] PCa treated right away_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +105003131,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +106003131,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +107003131,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +108003131,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +109003131,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +110003131,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +111003131,111,[PIONEER T3] PCa under conservative management,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +112003131,112,[PIONEER T3a] PCa under conservative management_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +113003131,113,[PIONEER T4.1] Delayed Curative Management,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +114003131,114,[PIONEER T4.1a] Delayed Curative Management_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +115003131,115,[PIONEER T4.2] Delayed Palliative Management,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +116003131,116,[PIONEER T4.2a] Delayed Palliative Management_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +117003131,117,[PIONEER T4] PCa treated after conservative management ,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +118003131,118,[PIONEER T4a] PCa treated after conservative management_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +119003131,119,[PIONEER T5] Symptom post conservative management ,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +120003131,120,[PIONEER T5a] Symptom post conservative management_broad,313,with [PIONEER S13] Physical Therapy/Exercise,TwS +101003141,101,[PIONEER T1] Newly diagnosed Pca ,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +102003141,102,[PIONEER T1a] Newly diagnosed Pca_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +103003141,103,[PIONEER T2] PCa treated right away,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +104003141,104,[PIONEER T2a] PCa treated right away_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +105003141,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +106003141,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +107003141,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +108003141,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +109003141,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +110003141,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +111003141,111,[PIONEER T3] PCa under conservative management,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +112003141,112,[PIONEER T3a] PCa under conservative management_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +113003141,113,[PIONEER T4.1] Delayed Curative Management,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +114003141,114,[PIONEER T4.1a] Delayed Curative Management_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +115003141,115,[PIONEER T4.2] Delayed Palliative Management,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +116003141,116,[PIONEER T4.2a] Delayed Palliative Management_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +117003141,117,[PIONEER T4] PCa treated after conservative management ,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +118003141,118,[PIONEER T4a] PCa treated after conservative management_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +119003141,119,[PIONEER T5] Symptom post conservative management ,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +120003141,120,[PIONEER T5a] Symptom post conservative management_broad,314,with [PIONEER S14] Grade 1 (GS 2-6),TwS +101003151,101,[PIONEER T1] Newly diagnosed Pca ,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +102003151,102,[PIONEER T1a] Newly diagnosed Pca_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +103003151,103,[PIONEER T2] PCa treated right away,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +104003151,104,[PIONEER T2a] PCa treated right away_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +105003151,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +106003151,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +107003151,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +108003151,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +109003151,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +110003151,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +111003151,111,[PIONEER T3] PCa under conservative management,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +112003151,112,[PIONEER T3a] PCa under conservative management_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +113003151,113,[PIONEER T4.1] Delayed Curative Management,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +114003151,114,[PIONEER T4.1a] Delayed Curative Management_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +115003151,115,[PIONEER T4.2] Delayed Palliative Management,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +116003151,116,[PIONEER T4.2a] Delayed Palliative Management_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +117003151,117,[PIONEER T4] PCa treated after conservative management ,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +118003151,118,[PIONEER T4a] PCa treated after conservative management_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +119003151,119,[PIONEER T5] Symptom post conservative management ,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +120003151,120,[PIONEER T5a] Symptom post conservative management_broad,315,with [PIONEER S15] Grade 2 (GS 3+4),TwS +101003161,101,[PIONEER T1] Newly diagnosed Pca ,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +102003161,102,[PIONEER T1a] Newly diagnosed Pca_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +103003161,103,[PIONEER T2] PCa treated right away,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +104003161,104,[PIONEER T2a] PCa treated right away_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +105003161,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +106003161,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +107003161,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +108003161,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +109003161,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +110003161,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +111003161,111,[PIONEER T3] PCa under conservative management,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +112003161,112,[PIONEER T3a] PCa under conservative management_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +113003161,113,[PIONEER T4.1] Delayed Curative Management,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +114003161,114,[PIONEER T4.1a] Delayed Curative Management_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +115003161,115,[PIONEER T4.2] Delayed Palliative Management,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +116003161,116,[PIONEER T4.2a] Delayed Palliative Management_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +117003161,117,[PIONEER T4] PCa treated after conservative management ,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +118003161,118,[PIONEER T4a] PCa treated after conservative management_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +119003161,119,[PIONEER T5] Symptom post conservative management ,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +120003161,120,[PIONEER T5a] Symptom post conservative management_broad,316,with [PIONEER S16] Grade 3 (GS 4+3),TwS +101003171,101,[PIONEER T1] Newly diagnosed Pca ,317,with [PIONEER S17] Grade 4 (GS 8),TwS +102003171,102,[PIONEER T1a] Newly diagnosed Pca_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +103003171,103,[PIONEER T2] PCa treated right away,317,with [PIONEER S17] Grade 4 (GS 8),TwS +104003171,104,[PIONEER T2a] PCa treated right away_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +105003171,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,317,with [PIONEER S17] Grade 4 (GS 8),TwS +106003171,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +107003171,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,317,with [PIONEER S17] Grade 4 (GS 8),TwS +108003171,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +109003171,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,317,with [PIONEER S17] Grade 4 (GS 8),TwS +110003171,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +111003171,111,[PIONEER T3] PCa under conservative management,317,with [PIONEER S17] Grade 4 (GS 8),TwS +112003171,112,[PIONEER T3a] PCa under conservative management_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +113003171,113,[PIONEER T4.1] Delayed Curative Management,317,with [PIONEER S17] Grade 4 (GS 8),TwS +114003171,114,[PIONEER T4.1a] Delayed Curative Management_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +115003171,115,[PIONEER T4.2] Delayed Palliative Management,317,with [PIONEER S17] Grade 4 (GS 8),TwS +116003171,116,[PIONEER T4.2a] Delayed Palliative Management_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +117003171,117,[PIONEER T4] PCa treated after conservative management ,317,with [PIONEER S17] Grade 4 (GS 8),TwS +118003171,118,[PIONEER T4a] PCa treated after conservative management_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +119003171,119,[PIONEER T5] Symptom post conservative management ,317,with [PIONEER S17] Grade 4 (GS 8),TwS +120003171,120,[PIONEER T5a] Symptom post conservative management_broad,317,with [PIONEER S17] Grade 4 (GS 8),TwS +101003181,101,[PIONEER T1] Newly diagnosed Pca ,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +102003181,102,[PIONEER T1a] Newly diagnosed Pca_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +103003181,103,[PIONEER T2] PCa treated right away,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +104003181,104,[PIONEER T2a] PCa treated right away_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +105003181,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +106003181,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +107003181,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +108003181,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +109003181,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +110003181,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +111003181,111,[PIONEER T3] PCa under conservative management,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +112003181,112,[PIONEER T3a] PCa under conservative management_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +113003181,113,[PIONEER T4.1] Delayed Curative Management,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +114003181,114,[PIONEER T4.1a] Delayed Curative Management_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +115003181,115,[PIONEER T4.2] Delayed Palliative Management,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +116003181,116,[PIONEER T4.2a] Delayed Palliative Management_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +117003181,117,[PIONEER T4] PCa treated after conservative management ,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +118003181,118,[PIONEER T4a] PCa treated after conservative management_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +119003181,119,[PIONEER T5] Symptom post conservative management ,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +120003181,120,[PIONEER T5a] Symptom post conservative management_broad,318,with [PIONEER S18] Grade 5 (GS 9-10),TwS +101003191,101,[PIONEER T1] Newly diagnosed Pca ,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +102003191,102,[PIONEER T1a] Newly diagnosed Pca_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +103003191,103,[PIONEER T2] PCa treated right away,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +104003191,104,[PIONEER T2a] PCa treated right away_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +105003191,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +106003191,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +107003191,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +108003191,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +109003191,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +110003191,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +111003191,111,[PIONEER T3] PCa under conservative management,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +112003191,112,[PIONEER T3a] PCa under conservative management_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +113003191,113,[PIONEER T4.1] Delayed Curative Management,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +114003191,114,[PIONEER T4.1a] Delayed Curative Management_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +115003191,115,[PIONEER T4.2] Delayed Palliative Management,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +116003191,116,[PIONEER T4.2a] Delayed Palliative Management_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +117003191,117,[PIONEER T4] PCa treated after conservative management ,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +118003191,118,[PIONEER T4a] PCa treated after conservative management_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +119003191,119,[PIONEER T5] Symptom post conservative management ,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +120003191,120,[PIONEER T5a] Symptom post conservative management_broad,319,with [PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,TwS +101003201,101,[PIONEER T1] Newly diagnosed Pca ,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +102003201,102,[PIONEER T1a] Newly diagnosed Pca_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +103003201,103,[PIONEER T2] PCa treated right away,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +104003201,104,[PIONEER T2a] PCa treated right away_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +105003201,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +106003201,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +107003201,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +108003201,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +109003201,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +110003201,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +111003201,111,[PIONEER T3] PCa under conservative management,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +112003201,112,[PIONEER T3a] PCa under conservative management_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +113003201,113,[PIONEER T4.1] Delayed Curative Management,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +114003201,114,[PIONEER T4.1a] Delayed Curative Management_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +115003201,115,[PIONEER T4.2] Delayed Palliative Management,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +116003201,116,[PIONEER T4.2a] Delayed Palliative Management_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +117003201,117,[PIONEER T4] PCa treated after conservative management ,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +118003201,118,[PIONEER T4a] PCa treated after conservative management_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +119003201,119,[PIONEER T5] Symptom post conservative management ,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +120003201,120,[PIONEER T5a] Symptom post conservative management_broad,320,"with [PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2",TwS +101003211,101,[PIONEER T1] Newly diagnosed Pca ,321,with [PIONEER S21] Age at diagnosis <55,TwS +102003211,102,[PIONEER T1a] Newly diagnosed Pca_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +103003211,103,[PIONEER T2] PCa treated right away,321,with [PIONEER S21] Age at diagnosis <55,TwS +104003211,104,[PIONEER T2a] PCa treated right away_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +105003211,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,321,with [PIONEER S21] Age at diagnosis <55,TwS +106003211,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +107003211,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,321,with [PIONEER S21] Age at diagnosis <55,TwS +108003211,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +109003211,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,321,with [PIONEER S21] Age at diagnosis <55,TwS +110003211,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +111003211,111,[PIONEER T3] PCa under conservative management,321,with [PIONEER S21] Age at diagnosis <55,TwS +112003211,112,[PIONEER T3a] PCa under conservative management_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +113003211,113,[PIONEER T4.1] Delayed Curative Management,321,with [PIONEER S21] Age at diagnosis <55,TwS +114003211,114,[PIONEER T4.1a] Delayed Curative Management_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +115003211,115,[PIONEER T4.2] Delayed Palliative Management,321,with [PIONEER S21] Age at diagnosis <55,TwS +116003211,116,[PIONEER T4.2a] Delayed Palliative Management_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +117003211,117,[PIONEER T4] PCa treated after conservative management ,321,with [PIONEER S21] Age at diagnosis <55,TwS +118003211,118,[PIONEER T4a] PCa treated after conservative management_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +119003211,119,[PIONEER T5] Symptom post conservative management ,321,with [PIONEER S21] Age at diagnosis <55,TwS +120003211,120,[PIONEER T5a] Symptom post conservative management_broad,321,with [PIONEER S21] Age at diagnosis <55,TwS +101003221,101,[PIONEER T1] Newly diagnosed Pca ,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +102003221,102,[PIONEER T1a] Newly diagnosed Pca_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +103003221,103,[PIONEER T2] PCa treated right away,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +104003221,104,[PIONEER T2a] PCa treated right away_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +105003221,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +106003221,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +107003221,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +108003221,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +109003221,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +110003221,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +111003221,111,[PIONEER T3] PCa under conservative management,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +112003221,112,[PIONEER T3a] PCa under conservative management_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +113003221,113,[PIONEER T4.1] Delayed Curative Management,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +114003221,114,[PIONEER T4.1a] Delayed Curative Management_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +115003221,115,[PIONEER T4.2] Delayed Palliative Management,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +116003221,116,[PIONEER T4.2a] Delayed Palliative Management_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +117003221,117,[PIONEER T4] PCa treated after conservative management ,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +118003221,118,[PIONEER T4a] PCa treated after conservative management_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +119003221,119,[PIONEER T5] Symptom post conservative management ,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +120003221,120,[PIONEER T5a] Symptom post conservative management_broad,322,with [PIONEER S22] Age at diagnosis 55-80,TwS +101003231,101,[PIONEER T1] Newly diagnosed Pca ,323,with [PIONEER S23] Age at diagnosis >80,TwS +102003231,102,[PIONEER T1a] Newly diagnosed Pca_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +103003231,103,[PIONEER T2] PCa treated right away,323,with [PIONEER S23] Age at diagnosis >80,TwS +104003231,104,[PIONEER T2a] PCa treated right away_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +105003231,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,323,with [PIONEER S23] Age at diagnosis >80,TwS +106003231,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +107003231,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,323,with [PIONEER S23] Age at diagnosis >80,TwS +108003231,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +109003231,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,323,with [PIONEER S23] Age at diagnosis >80,TwS +110003231,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +111003231,111,[PIONEER T3] PCa under conservative management,323,with [PIONEER S23] Age at diagnosis >80,TwS +112003231,112,[PIONEER T3a] PCa under conservative management_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +113003231,113,[PIONEER T4.1] Delayed Curative Management,323,with [PIONEER S23] Age at diagnosis >80,TwS +114003231,114,[PIONEER T4.1a] Delayed Curative Management_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +115003231,115,[PIONEER T4.2] Delayed Palliative Management,323,with [PIONEER S23] Age at diagnosis >80,TwS +116003231,116,[PIONEER T4.2a] Delayed Palliative Management_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +117003231,117,[PIONEER T4] PCa treated after conservative management ,323,with [PIONEER S23] Age at diagnosis >80,TwS +118003231,118,[PIONEER T4a] PCa treated after conservative management_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +119003231,119,[PIONEER T5] Symptom post conservative management ,323,with [PIONEER S23] Age at diagnosis >80,TwS +120003231,120,[PIONEER T5a] Symptom post conservative management_broad,323,with [PIONEER S23] Age at diagnosis >80,TwS +101003241,101,[PIONEER T1] Newly diagnosed Pca ,324,with [PIONEER S24] Charlson CCI=0,TwS +102003241,102,[PIONEER T1a] Newly diagnosed Pca_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +103003241,103,[PIONEER T2] PCa treated right away,324,with [PIONEER S24] Charlson CCI=0,TwS +104003241,104,[PIONEER T2a] PCa treated right away_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +105003241,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,324,with [PIONEER S24] Charlson CCI=0,TwS +106003241,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +107003241,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,324,with [PIONEER S24] Charlson CCI=0,TwS +108003241,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +109003241,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,324,with [PIONEER S24] Charlson CCI=0,TwS +110003241,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +111003241,111,[PIONEER T3] PCa under conservative management,324,with [PIONEER S24] Charlson CCI=0,TwS +112003241,112,[PIONEER T3a] PCa under conservative management_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +113003241,113,[PIONEER T4.1] Delayed Curative Management,324,with [PIONEER S24] Charlson CCI=0,TwS +114003241,114,[PIONEER T4.1a] Delayed Curative Management_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +115003241,115,[PIONEER T4.2] Delayed Palliative Management,324,with [PIONEER S24] Charlson CCI=0,TwS +116003241,116,[PIONEER T4.2a] Delayed Palliative Management_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +117003241,117,[PIONEER T4] PCa treated after conservative management ,324,with [PIONEER S24] Charlson CCI=0,TwS +118003241,118,[PIONEER T4a] PCa treated after conservative management_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +119003241,119,[PIONEER T5] Symptom post conservative management ,324,with [PIONEER S24] Charlson CCI=0,TwS +120003241,120,[PIONEER T5a] Symptom post conservative management_broad,324,with [PIONEER S24] Charlson CCI=0,TwS +101003251,101,[PIONEER T1] Newly diagnosed Pca ,325,with [PIONEER S25] Charlson CCI=1,TwS +102003251,102,[PIONEER T1a] Newly diagnosed Pca_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +103003251,103,[PIONEER T2] PCa treated right away,325,with [PIONEER S25] Charlson CCI=1,TwS +104003251,104,[PIONEER T2a] PCa treated right away_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +105003251,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,325,with [PIONEER S25] Charlson CCI=1,TwS +106003251,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +107003251,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,325,with [PIONEER S25] Charlson CCI=1,TwS +108003251,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +109003251,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,325,with [PIONEER S25] Charlson CCI=1,TwS +110003251,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +111003251,111,[PIONEER T3] PCa under conservative management,325,with [PIONEER S25] Charlson CCI=1,TwS +112003251,112,[PIONEER T3a] PCa under conservative management_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +113003251,113,[PIONEER T4.1] Delayed Curative Management,325,with [PIONEER S25] Charlson CCI=1,TwS +114003251,114,[PIONEER T4.1a] Delayed Curative Management_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +115003251,115,[PIONEER T4.2] Delayed Palliative Management,325,with [PIONEER S25] Charlson CCI=1,TwS +116003251,116,[PIONEER T4.2a] Delayed Palliative Management_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +117003251,117,[PIONEER T4] PCa treated after conservative management ,325,with [PIONEER S25] Charlson CCI=1,TwS +118003251,118,[PIONEER T4a] PCa treated after conservative management_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +119003251,119,[PIONEER T5] Symptom post conservative management ,325,with [PIONEER S25] Charlson CCI=1,TwS +120003251,120,[PIONEER T5a] Symptom post conservative management_broad,325,with [PIONEER S25] Charlson CCI=1,TwS +101003261,101,[PIONEER T1] Newly diagnosed Pca ,326,with [PIONEER S26] Charlson CCI>=2,TwS +102003261,102,[PIONEER T1a] Newly diagnosed Pca_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +103003261,103,[PIONEER T2] PCa treated right away,326,with [PIONEER S26] Charlson CCI>=2,TwS +104003261,104,[PIONEER T2a] PCa treated right away_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +105003261,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,326,with [PIONEER S26] Charlson CCI>=2,TwS +106003261,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +107003261,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,326,with [PIONEER S26] Charlson CCI>=2,TwS +108003261,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +109003261,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,326,with [PIONEER S26] Charlson CCI>=2,TwS +110003261,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +111003261,111,[PIONEER T3] PCa under conservative management,326,with [PIONEER S26] Charlson CCI>=2,TwS +112003261,112,[PIONEER T3a] PCa under conservative management_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +113003261,113,[PIONEER T4.1] Delayed Curative Management,326,with [PIONEER S26] Charlson CCI>=2,TwS +114003261,114,[PIONEER T4.1a] Delayed Curative Management_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +115003261,115,[PIONEER T4.2] Delayed Palliative Management,326,with [PIONEER S26] Charlson CCI>=2,TwS +116003261,116,[PIONEER T4.2a] Delayed Palliative Management_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +117003261,117,[PIONEER T4] PCa treated after conservative management ,326,with [PIONEER S26] Charlson CCI>=2,TwS +118003261,118,[PIONEER T4a] PCa treated after conservative management_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +119003261,119,[PIONEER T5] Symptom post conservative management ,326,with [PIONEER S26] Charlson CCI>=2,TwS +120003261,120,[PIONEER T5a] Symptom post conservative management_broad,326,with [PIONEER S26] Charlson CCI>=2,TwS +101003271,101,[PIONEER T1] Newly diagnosed Pca ,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +102003271,102,[PIONEER T1a] Newly diagnosed Pca_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +103003271,103,[PIONEER T2] PCa treated right away,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +104003271,104,[PIONEER T2a] PCa treated right away_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +105003271,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +106003271,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +107003271,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +108003271,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +109003271,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +110003271,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +111003271,111,[PIONEER T3] PCa under conservative management,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +112003271,112,[PIONEER T3a] PCa under conservative management_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +113003271,113,[PIONEER T4.1] Delayed Curative Management,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +114003271,114,[PIONEER T4.1a] Delayed Curative Management_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +115003271,115,[PIONEER T4.2] Delayed Palliative Management,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +116003271,116,[PIONEER T4.2a] Delayed Palliative Management_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +117003271,117,[PIONEER T4] PCa treated after conservative management ,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +118003271,118,[PIONEER T4a] PCa treated after conservative management_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +119003271,119,[PIONEER T5] Symptom post conservative management ,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +120003271,120,[PIONEER T5a] Symptom post conservative management_broad,327,"with [PIONEER S27] Any malignancy, except malignant neoplasm of skin",TwS +101003281,101,[PIONEER T1] Newly diagnosed Pca ,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +102003281,102,[PIONEER T1a] Newly diagnosed Pca_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +103003281,103,[PIONEER T2] PCa treated right away,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +104003281,104,[PIONEER T2a] PCa treated right away_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +105003281,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +106003281,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +107003281,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +108003281,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +109003281,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +110003281,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +111003281,111,[PIONEER T3] PCa under conservative management,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +112003281,112,[PIONEER T3a] PCa under conservative management_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +113003281,113,[PIONEER T4.1] Delayed Curative Management,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +114003281,114,[PIONEER T4.1a] Delayed Curative Management_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +115003281,115,[PIONEER T4.2] Delayed Palliative Management,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +116003281,116,[PIONEER T4.2a] Delayed Palliative Management_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +117003281,117,[PIONEER T4] PCa treated after conservative management ,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +118003281,118,[PIONEER T4a] PCa treated after conservative management_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +119003281,119,[PIONEER T5] Symptom post conservative management ,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +120003281,120,[PIONEER T5a] Symptom post conservative management_broad,328,with [PIONEER S31] Total Cardiovascular Disease Event,TwS +101003291,101,[PIONEER T1] Newly diagnosed Pca ,329,with [PIONEER S32] Stroke,TwS +102003291,102,[PIONEER T1a] Newly diagnosed Pca_broad,329,with [PIONEER S32] Stroke,TwS +103003291,103,[PIONEER T2] PCa treated right away,329,with [PIONEER S32] Stroke,TwS +104003291,104,[PIONEER T2a] PCa treated right away_broad,329,with [PIONEER S32] Stroke,TwS +105003291,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,329,with [PIONEER S32] Stroke,TwS +106003291,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,329,with [PIONEER S32] Stroke,TwS +107003291,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,329,with [PIONEER S32] Stroke,TwS +108003291,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,329,with [PIONEER S32] Stroke,TwS +109003291,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,329,with [PIONEER S32] Stroke,TwS +110003291,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,329,with [PIONEER S32] Stroke,TwS +111003291,111,[PIONEER T3] PCa under conservative management,329,with [PIONEER S32] Stroke,TwS +112003291,112,[PIONEER T3a] PCa under conservative management_broad,329,with [PIONEER S32] Stroke,TwS +113003291,113,[PIONEER T4.1] Delayed Curative Management,329,with [PIONEER S32] Stroke,TwS +114003291,114,[PIONEER T4.1a] Delayed Curative Management_broad,329,with [PIONEER S32] Stroke,TwS +115003291,115,[PIONEER T4.2] Delayed Palliative Management,329,with [PIONEER S32] Stroke,TwS +116003291,116,[PIONEER T4.2a] Delayed Palliative Management_broad,329,with [PIONEER S32] Stroke,TwS +117003291,117,[PIONEER T4] PCa treated after conservative management ,329,with [PIONEER S32] Stroke,TwS +118003291,118,[PIONEER T4a] PCa treated after conservative management_broad,329,with [PIONEER S32] Stroke,TwS +119003291,119,[PIONEER T5] Symptom post conservative management ,329,with [PIONEER S32] Stroke,TwS +120003291,120,[PIONEER T5a] Symptom post conservative management_broad,329,with [PIONEER S32] Stroke,TwS +101003301,101,[PIONEER T1] Newly diagnosed Pca ,330,with [PIONEER S33] Type 2 Diabetes,TwS +102003301,102,[PIONEER T1a] Newly diagnosed Pca_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +103003301,103,[PIONEER T2] PCa treated right away,330,with [PIONEER S33] Type 2 Diabetes,TwS +104003301,104,[PIONEER T2a] PCa treated right away_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +105003301,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,330,with [PIONEER S33] Type 2 Diabetes,TwS +106003301,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +107003301,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,330,with [PIONEER S33] Type 2 Diabetes,TwS +108003301,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +109003301,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,330,with [PIONEER S33] Type 2 Diabetes,TwS +110003301,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +111003301,111,[PIONEER T3] PCa under conservative management,330,with [PIONEER S33] Type 2 Diabetes,TwS +112003301,112,[PIONEER T3a] PCa under conservative management_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +113003301,113,[PIONEER T4.1] Delayed Curative Management,330,with [PIONEER S33] Type 2 Diabetes,TwS +114003301,114,[PIONEER T4.1a] Delayed Curative Management_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +115003301,115,[PIONEER T4.2] Delayed Palliative Management,330,with [PIONEER S33] Type 2 Diabetes,TwS +116003301,116,[PIONEER T4.2a] Delayed Palliative Management_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +117003301,117,[PIONEER T4] PCa treated after conservative management ,330,with [PIONEER S33] Type 2 Diabetes,TwS +118003301,118,[PIONEER T4a] PCa treated after conservative management_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +119003301,119,[PIONEER T5] Symptom post conservative management ,330,with [PIONEER S33] Type 2 Diabetes,TwS +120003301,120,[PIONEER T5a] Symptom post conservative management_broad,330,with [PIONEER S33] Type 2 Diabetes,TwS +101003311,101,[PIONEER T1] Newly diagnosed Pca ,331,with [PIONEER S34] Hypertension,TwS +102003311,102,[PIONEER T1a] Newly diagnosed Pca_broad,331,with [PIONEER S34] Hypertension,TwS +103003311,103,[PIONEER T2] PCa treated right away,331,with [PIONEER S34] Hypertension,TwS +104003311,104,[PIONEER T2a] PCa treated right away_broad,331,with [PIONEER S34] Hypertension,TwS +105003311,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,331,with [PIONEER S34] Hypertension,TwS +106003311,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,331,with [PIONEER S34] Hypertension,TwS +107003311,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,331,with [PIONEER S34] Hypertension,TwS +108003311,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,331,with [PIONEER S34] Hypertension,TwS +109003311,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,331,with [PIONEER S34] Hypertension,TwS +110003311,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,331,with [PIONEER S34] Hypertension,TwS +111003311,111,[PIONEER T3] PCa under conservative management,331,with [PIONEER S34] Hypertension,TwS +112003311,112,[PIONEER T3a] PCa under conservative management_broad,331,with [PIONEER S34] Hypertension,TwS +113003311,113,[PIONEER T4.1] Delayed Curative Management,331,with [PIONEER S34] Hypertension,TwS +114003311,114,[PIONEER T4.1a] Delayed Curative Management_broad,331,with [PIONEER S34] Hypertension,TwS +115003311,115,[PIONEER T4.2] Delayed Palliative Management,331,with [PIONEER S34] Hypertension,TwS +116003311,116,[PIONEER T4.2a] Delayed Palliative Management_broad,331,with [PIONEER S34] Hypertension,TwS +117003311,117,[PIONEER T4] PCa treated after conservative management ,331,with [PIONEER S34] Hypertension,TwS +118003311,118,[PIONEER T4a] PCa treated after conservative management_broad,331,with [PIONEER S34] Hypertension,TwS +119003311,119,[PIONEER T5] Symptom post conservative management ,331,with [PIONEER S34] Hypertension,TwS +120003311,120,[PIONEER T5a] Symptom post conservative management_broad,331,with [PIONEER S34] Hypertension,TwS +101003321,101,[PIONEER T1] Newly diagnosed Pca ,332,with [PIONEER S35] Obesity,TwS +102003321,102,[PIONEER T1a] Newly diagnosed Pca_broad,332,with [PIONEER S35] Obesity,TwS +103003321,103,[PIONEER T2] PCa treated right away,332,with [PIONEER S35] Obesity,TwS +104003321,104,[PIONEER T2a] PCa treated right away_broad,332,with [PIONEER S35] Obesity,TwS +105003321,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,332,with [PIONEER S35] Obesity,TwS +106003321,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,332,with [PIONEER S35] Obesity,TwS +107003321,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,332,with [PIONEER S35] Obesity,TwS +108003321,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,332,with [PIONEER S35] Obesity,TwS +109003321,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,332,with [PIONEER S35] Obesity,TwS +110003321,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,332,with [PIONEER S35] Obesity,TwS +111003321,111,[PIONEER T3] PCa under conservative management,332,with [PIONEER S35] Obesity,TwS +112003321,112,[PIONEER T3a] PCa under conservative management_broad,332,with [PIONEER S35] Obesity,TwS +113003321,113,[PIONEER T4.1] Delayed Curative Management,332,with [PIONEER S35] Obesity,TwS +114003321,114,[PIONEER T4.1a] Delayed Curative Management_broad,332,with [PIONEER S35] Obesity,TwS +115003321,115,[PIONEER T4.2] Delayed Palliative Management,332,with [PIONEER S35] Obesity,TwS +116003321,116,[PIONEER T4.2a] Delayed Palliative Management_broad,332,with [PIONEER S35] Obesity,TwS +117003321,117,[PIONEER T4] PCa treated after conservative management ,332,with [PIONEER S35] Obesity,TwS +118003321,118,[PIONEER T4a] PCa treated after conservative management_broad,332,with [PIONEER S35] Obesity,TwS +119003321,119,[PIONEER T5] Symptom post conservative management ,332,with [PIONEER S35] Obesity,TwS +120003321,120,[PIONEER T5a] Symptom post conservative management_broad,332,with [PIONEER S35] Obesity,TwS +101003331,101,[PIONEER T1] Newly diagnosed Pca ,333,with [PIONEER S36] VTE,TwS +102003331,102,[PIONEER T1a] Newly diagnosed Pca_broad,333,with [PIONEER S36] VTE,TwS +103003331,103,[PIONEER T2] PCa treated right away,333,with [PIONEER S36] VTE,TwS +104003331,104,[PIONEER T2a] PCa treated right away_broad,333,with [PIONEER S36] VTE,TwS +105003331,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,333,with [PIONEER S36] VTE,TwS +106003331,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,333,with [PIONEER S36] VTE,TwS +107003331,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,333,with [PIONEER S36] VTE,TwS +108003331,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,333,with [PIONEER S36] VTE,TwS +109003331,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,333,with [PIONEER S36] VTE,TwS +110003331,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,333,with [PIONEER S36] VTE,TwS +111003331,111,[PIONEER T3] PCa under conservative management,333,with [PIONEER S36] VTE,TwS +112003331,112,[PIONEER T3a] PCa under conservative management_broad,333,with [PIONEER S36] VTE,TwS +113003331,113,[PIONEER T4.1] Delayed Curative Management,333,with [PIONEER S36] VTE,TwS +114003331,114,[PIONEER T4.1a] Delayed Curative Management_broad,333,with [PIONEER S36] VTE,TwS +115003331,115,[PIONEER T4.2] Delayed Palliative Management,333,with [PIONEER S36] VTE,TwS +116003331,116,[PIONEER T4.2a] Delayed Palliative Management_broad,333,with [PIONEER S36] VTE,TwS +117003331,117,[PIONEER T4] PCa treated after conservative management ,333,with [PIONEER S36] VTE,TwS +118003331,118,[PIONEER T4a] PCa treated after conservative management_broad,333,with [PIONEER S36] VTE,TwS +119003331,119,[PIONEER T5] Symptom post conservative management ,333,with [PIONEER S36] VTE,TwS +120003331,120,[PIONEER T5a] Symptom post conservative management_broad,333,with [PIONEER S36] VTE,TwS +101003341,101,[PIONEER T1] Newly diagnosed Pca ,334,with [PIONEER S28] Performance status ECOG=0,TwS +102003341,102,[PIONEER T1a] Newly diagnosed Pca_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +103003341,103,[PIONEER T2] PCa treated right away,334,with [PIONEER S28] Performance status ECOG=0,TwS +104003341,104,[PIONEER T2a] PCa treated right away_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +105003341,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,334,with [PIONEER S28] Performance status ECOG=0,TwS +106003341,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +107003341,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,334,with [PIONEER S28] Performance status ECOG=0,TwS +108003341,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +109003341,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,334,with [PIONEER S28] Performance status ECOG=0,TwS +110003341,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +111003341,111,[PIONEER T3] PCa under conservative management,334,with [PIONEER S28] Performance status ECOG=0,TwS +112003341,112,[PIONEER T3a] PCa under conservative management_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +113003341,113,[PIONEER T4.1] Delayed Curative Management,334,with [PIONEER S28] Performance status ECOG=0,TwS +114003341,114,[PIONEER T4.1a] Delayed Curative Management_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +115003341,115,[PIONEER T4.2] Delayed Palliative Management,334,with [PIONEER S28] Performance status ECOG=0,TwS +116003341,116,[PIONEER T4.2a] Delayed Palliative Management_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +117003341,117,[PIONEER T4] PCa treated after conservative management ,334,with [PIONEER S28] Performance status ECOG=0,TwS +118003341,118,[PIONEER T4a] PCa treated after conservative management_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +119003341,119,[PIONEER T5] Symptom post conservative management ,334,with [PIONEER S28] Performance status ECOG=0,TwS +120003341,120,[PIONEER T5a] Symptom post conservative management_broad,334,with [PIONEER S28] Performance status ECOG=0,TwS +101003351,101,[PIONEER T1] Newly diagnosed Pca ,335,with [PIONEER S29] Performance status ECOG=1,TwS +102003351,102,[PIONEER T1a] Newly diagnosed Pca_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +103003351,103,[PIONEER T2] PCa treated right away,335,with [PIONEER S29] Performance status ECOG=1,TwS +104003351,104,[PIONEER T2a] PCa treated right away_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +105003351,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,335,with [PIONEER S29] Performance status ECOG=1,TwS +106003351,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +107003351,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,335,with [PIONEER S29] Performance status ECOG=1,TwS +108003351,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +109003351,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,335,with [PIONEER S29] Performance status ECOG=1,TwS +110003351,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +111003351,111,[PIONEER T3] PCa under conservative management,335,with [PIONEER S29] Performance status ECOG=1,TwS +112003351,112,[PIONEER T3a] PCa under conservative management_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +113003351,113,[PIONEER T4.1] Delayed Curative Management,335,with [PIONEER S29] Performance status ECOG=1,TwS +114003351,114,[PIONEER T4.1a] Delayed Curative Management_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +115003351,115,[PIONEER T4.2] Delayed Palliative Management,335,with [PIONEER S29] Performance status ECOG=1,TwS +116003351,116,[PIONEER T4.2a] Delayed Palliative Management_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +117003351,117,[PIONEER T4] PCa treated after conservative management ,335,with [PIONEER S29] Performance status ECOG=1,TwS +118003351,118,[PIONEER T4a] PCa treated after conservative management_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +119003351,119,[PIONEER T5] Symptom post conservative management ,335,with [PIONEER S29] Performance status ECOG=1,TwS +120003351,120,[PIONEER T5a] Symptom post conservative management_broad,335,with [PIONEER S29] Performance status ECOG=1,TwS +101003361,101,[PIONEER T1] Newly diagnosed Pca ,336,with [PIONEER S30] Performance status ECOG=2+,TwS +102003361,102,[PIONEER T1a] Newly diagnosed Pca_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +103003361,103,[PIONEER T2] PCa treated right away,336,with [PIONEER S30] Performance status ECOG=2+,TwS +104003361,104,[PIONEER T2a] PCa treated right away_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +105003361,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,336,with [PIONEER S30] Performance status ECOG=2+,TwS +106003361,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +107003361,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,336,with [PIONEER S30] Performance status ECOG=2+,TwS +108003361,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +109003361,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,336,with [PIONEER S30] Performance status ECOG=2+,TwS +110003361,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +111003361,111,[PIONEER T3] PCa under conservative management,336,with [PIONEER S30] Performance status ECOG=2+,TwS +112003361,112,[PIONEER T3a] PCa under conservative management_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +113003361,113,[PIONEER T4.1] Delayed Curative Management,336,with [PIONEER S30] Performance status ECOG=2+,TwS +114003361,114,[PIONEER T4.1a] Delayed Curative Management_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +115003361,115,[PIONEER T4.2] Delayed Palliative Management,336,with [PIONEER S30] Performance status ECOG=2+,TwS +116003361,116,[PIONEER T4.2a] Delayed Palliative Management_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +117003361,117,[PIONEER T4] PCa treated after conservative management ,336,with [PIONEER S30] Performance status ECOG=2+,TwS +118003361,118,[PIONEER T4a] PCa treated after conservative management_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +119003361,119,[PIONEER T5] Symptom post conservative management ,336,with [PIONEER S30] Performance status ECOG=2+,TwS +120003361,120,[PIONEER T5a] Symptom post conservative management_broad,336,with [PIONEER S30] Performance status ECOG=2+,TwS +101003371,101,[PIONEER T1] Newly diagnosed Pca ,337,with [PIONEER S37] Anxiety,TwS +102003371,102,[PIONEER T1a] Newly diagnosed Pca_broad,337,with [PIONEER S37] Anxiety,TwS +103003371,103,[PIONEER T2] PCa treated right away,337,with [PIONEER S37] Anxiety,TwS +104003371,104,[PIONEER T2a] PCa treated right away_broad,337,with [PIONEER S37] Anxiety,TwS +105003371,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,337,with [PIONEER S37] Anxiety,TwS +106003371,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,337,with [PIONEER S37] Anxiety,TwS +107003371,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,337,with [PIONEER S37] Anxiety,TwS +108003371,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,337,with [PIONEER S37] Anxiety,TwS +109003371,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,337,with [PIONEER S37] Anxiety,TwS +110003371,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,337,with [PIONEER S37] Anxiety,TwS +111003371,111,[PIONEER T3] PCa under conservative management,337,with [PIONEER S37] Anxiety,TwS +112003371,112,[PIONEER T3a] PCa under conservative management_broad,337,with [PIONEER S37] Anxiety,TwS +113003371,113,[PIONEER T4.1] Delayed Curative Management,337,with [PIONEER S37] Anxiety,TwS +114003371,114,[PIONEER T4.1a] Delayed Curative Management_broad,337,with [PIONEER S37] Anxiety,TwS +115003371,115,[PIONEER T4.2] Delayed Palliative Management,337,with [PIONEER S37] Anxiety,TwS +116003371,116,[PIONEER T4.2a] Delayed Palliative Management_broad,337,with [PIONEER S37] Anxiety,TwS +117003371,117,[PIONEER T4] PCa treated after conservative management ,337,with [PIONEER S37] Anxiety,TwS +118003371,118,[PIONEER T4a] PCa treated after conservative management_broad,337,with [PIONEER S37] Anxiety,TwS +119003371,119,[PIONEER T5] Symptom post conservative management ,337,with [PIONEER S37] Anxiety,TwS +120003371,120,[PIONEER T5a] Symptom post conservative management_broad,337,with [PIONEER S37] Anxiety,TwS +101003381,101,[PIONEER T1] Newly diagnosed Pca ,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +102003381,102,[PIONEER T1a] Newly diagnosed Pca_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +103003381,103,[PIONEER T2] PCa treated right away,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +104003381,104,[PIONEER T2a] PCa treated right away_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +105003381,105,[PIONEER T3.1] PCa high/intermediate risk conservative management,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +106003381,106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +107003381,107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +108003381,108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +109003381,109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +110003381,110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +111003381,111,[PIONEER T3] PCa under conservative management,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +112003381,112,[PIONEER T3a] PCa under conservative management_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +113003381,113,[PIONEER T4.1] Delayed Curative Management,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +114003381,114,[PIONEER T4.1a] Delayed Curative Management_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +115003381,115,[PIONEER T4.2] Delayed Palliative Management,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +116003381,116,[PIONEER T4.2a] Delayed Palliative Management_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +117003381,117,[PIONEER T4] PCa treated after conservative management ,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +118003381,118,[PIONEER T4a] PCa treated after conservative management_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +119003381,119,[PIONEER T5] Symptom post conservative management ,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS +120003381,120,[PIONEER T5a] Symptom post conservative management_broad,338,with [PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),TwS diff --git a/PioneerWatchfulWaiting/cohorts.csv b/PioneerWatchfulWaiting/cohorts.csv index 2a8c637f..84804dae 100644 --- a/PioneerWatchfulWaiting/cohorts.csv +++ b/PioneerWatchfulWaiting/cohorts.csv @@ -1 +1,66 @@ -cohortId,name,atlasId,circeDef +cohortId, name, atlasID, circeDef +101,[PIONEER T1] Newly diagnosed Pca, 47, TRUE +103,[PIONEER T2] PCa treated right away, 49, TRUE +111,[PIONEER T3] PCa under conservative management,137,TRUE +117,[PIONEER T4] PCa treated after conservative management ,143,TRUE +105,[PIONEER T3.1] PCa high/intermediate risk conservative management,138,TRUE +107,[PIONEER T3.2] PCa low risk grade conservative management and no intense monitoring,139,TRUE +109,[PIONEER T3.3] PCa low risk grade conservative management and intense monitoring,140,TRUE +113,[PIONEER T4.1] Delayed Curative Management,144,TRUE +115,[PIONEER T4.2] Delayed Palliative Management,145,TRUE +102,[PIONEER T1a] Newly diagnosed Pca_broad,141,TRUE +104,[PIONEER T2a] PCa treated right away_broad,142,TRUE +112,[PIONEER T3a] PCa under conservative management_broad,125,TRUE +118,[PIONEER T4a] PCa treated after conservative management_broad,129,TRUE +106,[PIONEER T3.1a] PCa high/intermediate risk conservative managemetn_broad,126,TRUE +108,[PIONEER T3.2a] PCa low risk grade conservative management and no intense monitoring_broad,127,TRUE +110,[PIONEER T3.3a] PCa low risk grade conservative management and intense monitoring_broad,128,TRUE +114,[PIONEER T4.1a] Delayed Curative Management_broad,131,TRUE +116,[PIONEER T4.2a] Delayed Palliative Management_broad,132,TRUE +119,[PIONEER T5] Symptom post conservative management ,168,TRUE +120,[PIONEER T5a] Symptom post conservative management_broad,167,TRUE +202,[PIONEER O1] Death,46,TRUE +201,[PIONEER O2] Symptomatic progression ,45,TRUE +203,[PIONEER O3] Treatment initiation,61,TRUE +204,[PIONEER O4] Curative treatment,73,TRUE +205,[PIONEER O5] Palliative treatment ,74,TRUE +206,[PIONEER O6] Hospitalization,87,TRUE +207,[PIONEER O7] ED visit,90,TRUE +301,[PIONEER S1] EAU High Risk,52,TRUE +302,[PIONEER S2] EAU Low Risk,53,TRUE +303,[PIONEER S3] EAU Intermediate Risk,54,TRUE +304,[PIONEER S4] Metastatic PCa,55,TRUE +305,[PIONEER S5] Locally Advanced PCa,56,TRUE +306,[PIONEER S6] localized PCa,57,TRUE +307,[PIONEER S7] PSA >20 at Diagnosis ,58,TRUE +308,[PIONEER S8] PSA <10 at Diagnosis,59,TRUE +309,[PIONEER S9] PSA 10-20 at Diagnosis,60,TRUE +310,[PIONEER S10] Stage cT1 at Dx,63,TRUE +311,[PIONEER S11] Stage cT2 at Dx,64,TRUE +312,[PIONEER S12] Stage cT3/cT4 at Dx,65,TRUE +313,[PIONEER S13] Physical Therapy/Exercise,112,TRUE +314,[PIONEER S14] Grade 1 (GS 2-6),67,TRUE +315,[PIONEER S15] Grade 2 (GS 3+4),68,TRUE +316,[PIONEER S16] Grade 3 (GS 4+3),69,TRUE +317,[PIONEER S17] Grade 4 (GS 8),70,TRUE +318,[PIONEER S18] Grade 5 (GS 9-10),71,TRUE +319,[PIONEER S19] Family history of Prostate cancer or history of family history of germline mutations,72,TRUE +"320,""[PIONEER S20] Mutation (germline or somatic) in BRCA2, BRCA1, ATM, MLH1, MSH1, MSH2, MSH6, CHEK2, RAD51B and PALB2 "",83,TRUE" +321,[PIONEER S21] Age at diagnosis <55,111,TRUE +322,[PIONEER S22] Age at diagnosis 55-80,110,TRUE +323,[PIONEER S23] Age at diagnosis >80,109,TRUE +324,[PIONEER S24] Charlson CCI=0,120,TRUE +325,[PIONEER S25] Charlson CCI=1,121,TRUE +326,[PIONEER S26] Charlson CCI>=2,122,TRUE +"327,""[PIONEER S27] Any malignancy, except malignant neoplasm of skin"",81,TRUE" +334,[PIONEER S28] Performance status ECOG=0,164,TRUE +335,[PIONEER S29] Performance status ECOG=1,165,TRUE +336,[PIONEER S30] Performance status ECOG=2+,166,TRUE +328,[PIONEER S31] Total Cardiovascular Disease Event,152,TRUE +329,[PIONEER S32] Stroke,153,TRUE +330,[PIONEER S33] Type 2 Diabetes,154,TRUE +331,[PIONEER S34] Hypertension,155,TRUE +332,[PIONEER S35] Obesity,156,TRUE +333,[PIONEER S36] VTE,157,TRUE +337,[PIONEER S37] Anxiety,158,TRUE +338,[PIONEER S38] Prevalent Asthma or Chronic obstructive pulmonary disease (COPD),159,TRUE \ No newline at end of file diff --git a/PioneerWatchfulWaiting/ggsurvtable.R b/PioneerWatchfulWaiting/ggsurvtable.R new file mode 100644 index 00000000..d7b408a9 --- /dev/null +++ b/PioneerWatchfulWaiting/ggsurvtable.R @@ -0,0 +1,261 @@ +cb_palette <- c("#000000", "#E69F00", "#56B4E9", "#009E73", "#F0E442", "#0072B2", "#D55E00", "#CC79A7") +ggsurvtable_custom <- function (fit, data = NULL, survtable = c("cumevents", "cumcensor", "risk.table"), + risk.table.type = c("absolute", "percentage", "abs_pct", "nrisk_cumcensor", "nrisk_cumevents"), + title = NULL, risk.table.title = NULL, cumevents.title = title, cumcensor.title = title, + color = "black", palette = cb_palette, break.time.by = NULL, xlim = NULL, + xscale = 1, xlab = "Time", ylab = "Strata", + xlog = FALSE, legend = "top", + legend.title = "Strata", legend.labs = NULL, + y.text = TRUE, y.text.col = TRUE, + fontsize = 4.5, font.family = "", + axes.offset = TRUE, + ggtheme = theme_survminer(), + tables.theme = ggtheme, ...) +{ + + if(is.data.frame(fit)){} + else if(.is_list(fit)){ + if(!all(c("time", "table") %in% names(fit))) + stop("fit should contain the following component: time and table") + } + else if(!.is_survfit(fit)) + stop("Can't handle an object of class ", class(fit)) + + # Define time axis breaks + #::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + xmin <- ifelse(xlog, min(c(1, fit$time)), 0) + if(is.null(xlim)) xlim <- c(xmin, max(fit$time)) + times <- .get_default_breaks(fit$time, .log = xlog) + if(!is.null(break.time.by) &!xlog) times <- seq(0, max(c(fit$time, xlim)), by = break.time.by) + + + + # Surv summary at specific time points + #::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + # if(.is_survfit(fit)){ + # data <- .get_data(fit, data = data) + # survsummary <- .get_timepoints_survsummary(fit, data, times) + # } + # else if(.is_list(fit)){ + # survsummary <- fit$table + # } + else if(inherits(fit, "data.frame")){ + survsummary <- as.data.frame(.get_timepoints_survsummary(fit, data, times)) + } + + opts <- list( + survsummary = survsummary, times = times, + survtable = survtable, risk.table.type = risk.table.type, color = color, palette = cb_palette, + xlim = xlim, xscale = xscale, + title = title, xlab = xlab, ylab = ylab, xlog = xlog, + legend = legend, legend.title = legend.title, legend.labs = legend.labs, + y.text = y.text, y.text.col = y.text.col, + fontsize = fontsize, font.family = font.family, + axes.offset = axes.offset, + ggtheme = ggtheme, tables.theme = tables.theme,...) + + res <- list() + time <- strata <- label <- n.event <- cum.n.event <- NULL + + # Ploting the cumulative number of events table + #::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + + if("cumevents" %in% survtable){ + opts$survtable = "cumevents" + opts$title <- ifelse(is.null(cumevents.title), + "Cumulative number of events", cumevents.title) + res$cumevents <- do.call(.plot_survtable, opts) + + } + + if("cumcensor" %in% survtable){ + opts$survtable = "cumcensor" + opts$title <- ifelse(is.null(cumcensor.title), + "Cumulative number of events", cumcensor.title) + res$cumcensor <- do.call(.plot_survtable, opts) + + } + if("risk.table" %in% survtable){ + opts$survtable = "risk.table" + if(is.null(risk.table.title)) opts$title <- NULL + else opts$title <- risk.table.title + res$risk.table <- do.call(.plot_survtable, opts) + } + + + if(length(res) == 1) res <- res[[1]] + res +} + + + + + + + + +# Helper function to plot a specific survival table +.plot_survtable <- function (survsummary, times, survtable = c("cumevents", "risk.table", "cumcensor"), + risk.table.type = c("absolute", "percentage", "abs_pct", "nrisk_cumcensor", "nrisk_cumevents"), + color = "black", palette = cb_palette, xlim = NULL, + xscale = 1, + title = NULL, xlab = "Time", ylab = "Strata", + xlog = FALSE, legend = "top", + legend.title = "Strata", legend.labs = NULL, + y.text = TRUE, y.text.col = TRUE, fontsize = 4.5, + font.family = "", + axes.offset = TRUE, + ggtheme = theme_survminer(), tables.theme = ggtheme, + ...) +{ + + survtable <- match.arg(survtable) + risk.table.type <- match.arg(risk.table.type) + + # Defining plot title + #::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + if(is.null(title)){ + + if(survtable == "risk.table"){ + risk.table.type <- match.arg(risk.table.type) + title <- switch(risk.table.type, + absolute = "Number at risk", + percentage = "Percentage at risk", + abs_pct = "Number at risk: n (%)", + nrisk_cumcensor = "Number at risk (number censored)", + nrisk_cumevents = "Number at risk (number of events)", + "Number at risk") + + } + else + title <- switch(survtable, + cumevents = "Cumulative number of events", + cumcensor = "Number of censored subjects" + ) + } + + # Legend labels + #::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + if(is.null(color)) + color <- .strata.var <- "strata" + else if(color %in% colnames(survsummary)) + .strata.var <- color + else + .strata.var <- "strata" + + # Number of strata and strata names + .strata <- survsummary[, .strata.var] + strata_names <- .levels(.strata) + n.strata <- length(strata_names) + + # Check legend labels and title + if(!is.null(legend.labs)){ + if(n.strata != length(legend.labs)) + warning("The length of legend.labs should be ", n.strata ) + else survsummary$strata <- factor(survsummary$strata, labels = legend.labs) + } + else if(is.null(legend.labs)) + legend.labs <- strata_names + + + + # Adjust table y axis tick labels in case of long strata + #::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + yticklabs <- rev(levels(survsummary$strata)) + n_strata <- length(levels(survsummary$strata)) + if(!y.text) yticklabs <- rep("\\-", n_strata) + + time <- strata <- label <- n.event <- cum.n.event <- cum.n.censor<- NULL + + # Ploting the cumulative number of events table + #::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + if(survtable == "cumevents"){ + mapping <- ggplot2::aes(x = time, y = rev(strata), + label = cum.n.event, shape = rev(strata)) + } + else if (survtable == "cumcensor"){ + mapping <- ggplot2::aes(x = time, y = rev(strata), + label = cum.n.censor, shape = rev(strata)) + + } + else if (survtable == "risk.table"){ + # risk table labels depending on the type argument + pct.risk <- abs_pct.risk <- n.risk <- NULL + llabels <- switch(risk.table.type, + percentage = round(survsummary$n.risk*100/survsummary$strata_size), + abs_pct = paste0(survsummary$n.risk, " (", survsummary$pct.risk, ")"), + nrisk_cumcensor = paste0(survsummary$n.risk, " (", survsummary$cum.n.censor, ")"), + nrisk_cumevents = paste0(survsummary$n.risk, " (", survsummary$cum.n.event, ")"), + survsummary$n.risk + ) + survsummary$llabels <- llabels + mapping <- ggplot2::aes(x = time, y = rev(strata), + label = llabels, shape = rev(strata)) + + } + + + # Plotting survival table + #::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + .expand <- ggplot2::waiver() + # Tables labels Offset from origing + if(!axes.offset){ + .expand <- c(0,0) + offset <- max(xlim)/30 + survsummary <- survsummary %>% + dplyr::mutate(time = ifelse(time == 0, offset, time)) + } + + p <- ggplot2::ggplot(survsummary, mapping) + + ggplot2::scale_shape_manual(values = 1:length(levels(survsummary$strata)))+ + ggpubr::geom_exec(ggplot2::geom_text, data = survsummary, size = fontsize, color = color, family = font.family) + + ggtheme + + ggplot2::scale_y_discrete(breaks = as.character(levels(survsummary$strata)),labels = yticklabs ) + + ggplot2::coord_cartesian(xlim = xlim) + + ggplot2::labs(title = title, x = xlab, y = ylab, color = legend.title, shape = legend.title) + + if (survtable == "risk.table") + p <- .set_risktable_gpar(p, ...) # For backward compatibility + + p <- ggpubr::ggpar(p, legend = legend, palette = palette,...) + + # Customize axis ticks + #::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + xticklabels <- .format_xticklabels(labels = times, xscale = xscale) + if(!xlog) p <- p + ggplot2::scale_x_continuous(breaks = times, labels = xticklabels, expand = .expand) + else p <- p + ggplot2::scale_x_continuous(breaks = times, + trans = "log10", labels = xticklabels) + + p <- p + tables.theme + + if(!y.text) { + p <- .set_large_dash_as_ytext(p) + } + + # Color table tick labels by strata + if(is.logical(y.text.col) & y.text.col[1] == TRUE){ + cols <- .extract_ggplot_colors(p, grp.levels = legend.labs) + p <- p + ggplot2::theme(axis.text.y = ggtext::element_markdown(colour = rev(cols))) + } + else if(is.character(y.text.col)) + p <- p + ggplot2::theme(axis.text.y = ggtext::element_markdown(colour = rev(y.text.col))) + + p + +} + + + +# For backward compatibility +# Specific graphical params to risk.table +.set_risktable_gpar <- function(p, ...){ + extra.params <- list(...) + ggpubr:::.labs(p, + font.main = extra.params$font.risk.table.title, + font.x = extra.params$font.risk.table.x, + font.y = extra.params$font.risk.table.y, + submain = extra.params$risk.table.subtitle, + caption = extra.params$risk.table.caption, + font.submain = extra.params$font.risk.table.subtitle, + font.caption = extra.params$font.risk.table.caption) +} diff --git a/PioneerWatchfulWaiting/global.R b/PioneerWatchfulWaiting/global.R index 385cbc7e..3ed87e4c 100644 --- a/PioneerWatchfulWaiting/global.R +++ b/PioneerWatchfulWaiting/global.R @@ -114,9 +114,26 @@ if (dataStorage == "database") { } } - if (exists("covariate")) { covariate <- unique(covariate) + covNameWithId <- grepl(': \\d\\d\\d$', covariate$covariateName) + if (any(covNameWithId)) { + # Temporary quick fix to replace cohortId with atlasName + cohorts <- readr::read_csv("./cohorts.csv", col_types = readr::cols()) + newCovariateName <- sapply(covariate$covariateName[covNameWithId], + function(x) { + cohortId <- substr(x, nchar(x)-2, nchar(x)) + cohort <- cohorts[cohorts$cohortId==cohortId,] + if (nrow(cohort) > 0) { + return(paste0(substr(x, 1, nchar(x)-3), cohort$name)) + } else { + # cohortId not found, return original + return(x) + } + } + ) + covariate$covariateName[covNameWithId] <- newCovariateName + } covariate$windowId <- as.numeric(substr(covariate$covariateId, nchar(covariate$covariateId), nchar(covariate$covariateId))) } @@ -127,11 +144,12 @@ domain <- rbind(domain,data.frame(name = "Cohort", covariateAnalysisId = c(10000 domain <- rbind(domain,data.frame(name = "Demographics", covariateAnalysisId = c(1:99))) domain <- rbind(domain,data.frame(name = "Drug", covariateAnalysisId = c(412))) domain <- rbind(domain,data.frame(name = "Condition", covariateAnalysisId = c(212))) +domain <- rbind(domain,data.frame(name = 'Procedure', covariateAnalysisId = c(712))) domain$name <- as.character(domain$name) domainName <- "All" -# This must match the featureTimeWindow.csv from the Charybdis study -timeWindow <- data.frame(windowId=c(1:4), name=c("-365d to -1d", "-30d to -1d", "index", "index to 30d")) +# This must match the featureTimeWindow.csv from the Pioneer study +timeWindow <- data.frame(windowId=c(1:3), name=c("index to 365", "366d to 730d", "731d+")) timeWindow$name <- as.character(timeWindow$name) cohortXref <- readr::read_csv("./cohortXref.csv", col_types = readr::cols()) @@ -167,3 +185,15 @@ dbTermsOfUse <- readr::read_csv("./databaseTermsOfUse.csv", col_types = readr::c colnames(dbTermsOfUse) <- SqlRender::snakeCaseToCamelCase(colnames(dbTermsOfUse)) database <- dplyr::left_join(database, dbTermsOfUse, by="databaseId") database <- database[order(database$databaseId),] + + +# Add Time to Event names and ids +ids <- unique(cohortTimeToEvent$outcomeId) +names <- unique(cohortStagingCount$name[cohortStagingCount$cohortId %in% ids]) +if(length(cohortStagingCount$name[cohortStagingCount$cohortId == max(ids)]) == 0){ + names <- c(names, 'Symptomatic progr. free surv.') +} + +KMIds <- data.frame(id = ids, + name = names) + diff --git a/PioneerWatchfulWaiting/md/terms_of_use.zip b/PioneerWatchfulWaiting/md/terms_of_use.zip new file mode 100644 index 00000000..38c04ddb Binary files /dev/null and b/PioneerWatchfulWaiting/md/terms_of_use.zip differ diff --git a/PioneerWatchfulWaiting/server.R b/PioneerWatchfulWaiting/server.R index 24d52784..ec1d9d7c 100644 --- a/PioneerWatchfulWaiting/server.R +++ b/PioneerWatchfulWaiting/server.R @@ -3,6 +3,10 @@ library(shinydashboard) library(DT) library(htmltools) source("PlotsAndTables.R") +source("utilities.R") +source("survplot_core.R") +source("ggsurvtable.R") + truncateStringDef <- function(columns, maxChars) { list( @@ -137,7 +141,8 @@ shinyServer(function(input, output, session) { # Filter Options ----- cohortIdTimeToEvent <- reactive({ - return(unlist(cohortXref[cohortXref$targetId %in% targetCohortIdTimeToEvent() & cohortXref$strataName %in% input$strataTimeToEvent,c("cohortId")])) + return(unlist(cohortXref[cohortXref$targetId %in% targetCohortIdTimeToEvent() + & cohortXref$strataName %in% input$strataTimeToEvent,c("cohortId")])) }) targetCohortIdTimeToEvent <- reactive({ @@ -145,7 +150,14 @@ shinyServer(function(input, output, session) { }) + cohortIdMetricsDistribution <- reactive({ + return(unlist(cohortXref[cohortXref$targetId %in% targetCohortIdMetricsDistribution() + & cohortXref$strataName %in% input$strataMetricsDistribution, c("cohortId")])) + }) + targetCohortIdMetricsDistribution <- reactive({ + return(targetCohort$targetId[targetCohort$targetName %in% input$targetMetricsDistribution]) + }) cohortIdList <- reactive({ @@ -269,79 +281,86 @@ shinyServer(function(input, output, session) { # timeToEvent----------------- - getSurvivalInfo <- reactive({ - table <- cohortCount[cohortCount$databaseId %in% input$databasesTimeToEvent & cohortCount$cohortId %in% cohortIdTimeToEvent(), ] - # print(cohortTimeToEvent) - return(table) - }) output$survivalHeader <- renderText({ - # print(cohortCount[cohortCount$databaseId %in% input$databases & cohortCount$cohortId %in% cohortIdTimeToEvent(), ][[1]]) paste(input$targetTimeToEvent, input$strataTimeToEvent, sep=" ") }) + output$dlTimeToEvent <- downloadHandler( + filename = function() { + "timeToEvent.csv" + }, + content = function(file) { + target_id <- cohortCount[cohortCount$databaseId %in% input$databasesTimeToEvent & + cohortCount$cohortId %in% cohortIdTimeToEvent(), ][[1]] + targetIdTimeToEventData <- cohortTimeToEvent %>% dplyr::filter(targetId == target_id, + databaseId == input$databasesTimeToEvent) + write.csv(targetIdTimeToEventData, file, row.names = FALSE, na = "") + } + ) + output$TimeToEventDeath <- renderPlot({ - target_id <- cohortCount[cohortCount$databaseId %in% input$databasesTimeToEvent & cohortCount$cohortId %in% cohortIdTimeToEvent(), ][[1]] - if (length(target_id) == 0){ + target_id <- cohortCount[cohortCount$databaseId %in% input$databasesTimeToEvent & + cohortCount$cohortId %in% cohortIdTimeToEvent(), ][[1]] + target_id_entries_num <- cohortCount[cohortCount$cohortId == target_id, "cohortEntries"][[1]] + + if (length(target_id) == 0 | target_id_entries_num <= 100 | is.null(input$KMPlot)){ plot <- ggplot2::ggplot() return(plot) } - - symptomsCohortId <- cohortStagingCount[cohortStagingCount$name == 'Symptoms', 'cohortId'][[1]] - deathCohortId <- cohortStagingCount[cohortStagingCount$name == 'Death', 'cohortId'][[1]] - treatmentCohortId <- cohortStagingCount[cohortStagingCount$name == 'Treatment Initiation', 'cohortId'][[1]] - - targetIdTimeToEvent <- cohortTimeToEvent %>% dplyr::filter(targetId == target_id) - if (length(symptomsCohortId)>0){ - dataBoth <- targetIdTimeToEvent %>% dplyr::filter(outcomeId == c(999999)) - } - else{ - dataBoth <- targetIdTimeToEvent %>% dplyr::filter(outcomeId == -1) - } - if (length(symptomsCohortId)>0){ - dataSymptoms <- targetIdTimeToEvent %>% dplyr::filter(outcomeId == symptomsCohortId) - } - else{ - dataSymptoms <- targetIdTimeToEvent %>% dplyr::filter(outcomeId == -1) - } - if (length(deathCohortId)>0){ - dataDeath <- targetIdTimeToEvent %>% dplyr::filter(outcomeId == deathCohortId) - } - else{ - dataDeath <- targetIdTimeToEvent %>% dplyr::filter(outcomeId == -1) - } - if (length(treatmentCohortId)>0){ - dataTreatment <- targetIdTimeToEvent %>% dplyr::filter(outcomeId == treatmentCohortId) - } - else{ - dataTreatment <- targetIdTimeToEvent %>% dplyr::filter(outcomeId == -1) - } + targetIdTimeToEventData <- cohortTimeToEvent %>% dplyr::filter(targetId == target_id, + databaseId == input$databasesTimeToEvent) - plot <- ggplot2::ggplot() - plot <- plot + ggplot2::geom_line(data = dataDeath, - ggplot2::aes(x = time, y = survival, color = as.factor(outcomeId)), - size = 2) - plot <- plot + ggplot2::geom_line(data = dataSymptoms, - ggplot2::aes(x = time, y = survival, color = as.factor(outcomeId)), - size = 2) - plot <- plot + ggplot2::geom_line(data = dataBoth, - ggplot2::aes(x = time, y = survival, color = as.factor(outcomeId)), - size = 2) - plot <- plot + ggplot2::geom_line(data = dataTreatment, - ggplot2::aes(x = time, y = survival, color = as.factor(outcomeId)), - size = 2) - plot <- plot + ggplot2::ylim(min(dataSymptoms$survival, dataDeath$survival, dataBoth$survival), 1) - plot <- plot + ggplot2::xlab('days') - plot <- plot + ggplot2::scale_color_hue(labels = c("Death", "Symptoms", "Death or Symptoms", "Treatment")) - plot <- plot + ggplot2::labs(color = "Time to Event \n") + accumulatedData <- data.frame(time = c(), surv = c(), n.censor = c(), + n.event = c(), upper = c(), lower = c()) + for(plotName in input$KMPlot){ + oId <- KMIds$id[KMIds$name == plotName] + data <- targetIdTimeToEventData %>% dplyr::filter(outcomeId == oId) + if (length(data) > 0){ + data <- as.data.frame(data[, c('time', 'surv', 'n.risk', 'n.censor', 'n.event', 'upper', 'lower')]) + data$strata <- plotName + } + else{ + data <- targetIdTimeToEventData %>% dplyr::filter(outcomeId == -1) + } + accumulatedData <- rbind(accumulatedData, data) + } + plot <- ggsurvplot_core(accumulatedData, + risk.table = "nrisk_cumcensor", + conf.int = TRUE, + legend.title = 'Event', + ylim = c(min(accumulatedData$lower), 1), + ggtheme = ggplot2::theme_bw() + ) + return(plot) }) - + # Metrics Distribution + output$metricsHeader <- renderText({ + paste(input$targetMetricsDistribution, input$strataMetricsDistribution, sep=" ") + }) + + + getMetricsTable <- reactive ({ + target_id <- cohortCount[cohortCount$databaseId %in% input$databasesMetricsDistribution + & cohortCount$cohortId %in% cohortIdMetricsDistribution(), ][[1]] + metricsTable <- metricsDistribution %>% dplyr::filter(cohortDefinitionId == target_id, + databaseId == input$databasesMetricsDistribution) + names(metricsTable)[names(metricsTable) == 'iqr'] <- 'IQR' + return(metricsTable[c('analysisName', 'IQR', 'minimum', 'q1', 'median', 'q3', 'maximum')]) + }) + + + output$metricsTable <- renderDataTable( + getMetricsTable() + ) + + # Cohort Counts --------- output$borderCohortCounts <- renderUI({ return(renderBorderTag()) diff --git a/PioneerWatchfulWaiting/survplot_core.R b/PioneerWatchfulWaiting/survplot_core.R new file mode 100644 index 00000000..c0ae3a53 --- /dev/null +++ b/PioneerWatchfulWaiting/survplot_core.R @@ -0,0 +1,258 @@ +ggsurvplot_core <- function(fit, data = NULL, d = NULL, fun = NULL, + color = NULL, palette = NULL, linetype = 1, + break.x.by = NULL, break.y.by = NULL, break.time.by = NULL, + surv.scale = c("default", "percent"), xscale = 1, + conf.int = FALSE, conf.int.fill = "gray", conf.int.style = "ribbon", + conf.int.alpha = 0.3, + censor = TRUE, censor.shape = "+", censor.size = 4.5, + pval = FALSE, pval.size = 5, pval.coord = c(NULL, NULL), + test.for.trend = FALSE, + pval.method = FALSE, pval.method.size = pval.size, pval.method.coord = c(NULL, NULL), + log.rank.weights = c("survdiff", "1", "n", "sqrtN", "S1", "S2", "FH_p=1_q=1"), + title = NULL, xlab = "Time", ylab = "Survival probability", + xlim = NULL, ylim = NULL, axes.offset = TRUE, + legend = c("top", "bottom", "left", "right", "none"), + legend.title = "Strata", legend.labs = NULL, + fontsize = 4.5, font.family = "", + tables.height = 0.25, tables.y.text = TRUE, tables.col = "black", + tables.y.text.col = TRUE, + risk.table = FALSE, risk.table.pos = c("out", "in"), risk.table.title = NULL, + risk.table.col = tables.col, risk.table.fontsize = fontsize, + risk.table.y.text = tables.y.text, + risk.table.y.text.col = tables.y.text.col, + risk.table.height = tables.height, surv.plot.height = 0.75, + ncensor.plot.height = tables.height, cumevents.height = tables.height, + cumcensor.height = tables.height, + ncensor.plot = FALSE, + ncensor.plot.title = NULL, + cumevents = FALSE, cumevents.col = tables.col, cumevents.title = NULL, + cumevents.y.text = tables.y.text, cumevents.y.text.col = tables.y.text.col, + cumcensor = FALSE, cumcensor.col = tables.col, cumcensor.title = NULL, + cumcensor.y.text = tables.y.text, cumcensor.y.text.col = tables.y.text.col, + surv.median.line = c("none", "hv", "h", "v"), + ggtheme = theme_survminer(), + tables.theme = ggtheme, + ... +){ + d <- fit + + # if(!inherits(fit, "survfit")) + # stop("Can't handle an object of class ", class(fit)) + surv.median.line <- match.arg(surv.median.line) + stopifnot(log.rank.weights %in% c("survdiff", "1", "n", "sqrtN", "S1", "S2","FH_p=1_q=1")) + log.rank.weights <- match.arg(log.rank.weights) + + # Make sure that user can do either ncensor.plot or cumcensor + # But not both + if(ncensor.plot & cumcensor){ + warning("Both ncensor.plot and cumsensor are TRUE.", + "In this case, we consider only cumcensor.", call. = FALSE) + ncensor.plot <- FALSE + } + if(cumcensor) ncensor.plot.height <- cumcensor.height + if(is.null(ncensor.plot.title)) + ncensor.plot.title <- "Number of censoring" + if(is.null(cumcensor.title)) + cumcensor.title <- "Cumulative number of censoring" + if(is.null(cumevents.title)) + cumevents.title <- "Cumulative number of events" + + # risk.table argument + +#============================================================== +#============================================================== + risk.table.pos <- match.arg(risk.table.pos) + risktable <- .parse_risk_table_arg(risk.table) + risk.table <- risktable$display + risk.table.type <- risktable$type + extra.params <- list(...) + + # Axes offset + .expand <- ggplot2::waiver() + if(!axes.offset) + .expand <- c(0, 0) + + + # Data + #:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + # data used to compute survfit + # data <- .get_data(fit, data = data, complain = FALSE) + # Data for survival plot + # d <- surv_summary(fit, data = data) + if(!is.null(fit$start.time)) d <- subset(d, d$time >= fit$start.time ) + + # Axis limits + xmin <- ifelse(.is_cloglog(fun), min(c(1, d$time)), 0) + if(!is.null(fit$start.time)) xmin <- fit$start.time + xmax <- .get_default_breaks(d$time, .log = .is_cloglog(fun)) %>% max() + if(is.null(xlim)) xlim <- c(xmin, xmax) + + # Main survival curves + #:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + p <- survminer::ggsurvplot_df(d, fun = fun, + color = color, palette = cb_palette, linetype = linetype, + break.x.by = break.x.by, break.time.by = break.time.by, break.y.by = break.y.by, + surv.scale = surv.scale, xscale = xscale, + conf.int = conf.int, conf.int.fill = conf.int.fill, conf.int.style = conf.int.style, + conf.int.alpha = conf.int.alpha, + censor = censor, censor.shape = censor.shape, censor.size = censor.size, + title = title, xlab = xlab, ylab = ylab, + xlim = xlim, ylim = ylim, axes.offset = axes.offset, + legend = legend, legend.title = legend.title, legend.labs = legend.labs, + ggtheme = ggtheme, ...) + + + + + # The main plot parameters, will be used to plot survival tables + pms <- attr(p, "parameters") + color <- surv.color <- pms$color <-cb_palette + + + res <- list(plot = p) + + # Extract strata colors used in survival curves + # Will be used to color the y.text of risk table and cumevents table + if(risk.table | cumevents | cumcensor | ncensor.plot){ + scurve_cols <- .extract_ggplot_colors (p, grp.levels = pms$legend.labs) + } + + + # The main plot parameters, will be used to plot survival tables + pms <- attr(p, "parameters") + surv.color <- pms$color + + pms$fit <- fit + pms$risk.table.type <- risk.table.type + pms$risk.table.title <- risk.table.title + pms$cumevents.title <- cumevents.title + pms$cumcensor.title <- cumcensor.title + pms$fontsize <- fontsize + pms$ggtheme <- ggtheme + pms$ylab <- pms$legend.title + pms$tables.theme <- tables.theme + pms$y.text <- tables.y.text + pms$color <- tables.col + pms$font.family <- font.family + pms$axes.offset <- axes.offset + + + # Add risk table + if(risk.table){ + if(risk.table.pos == "in") risk.table.col = surv.color + pms$color <- risk.table.col + pms$title <- risk.table.title + pms$y.text <- risk.table.y.text + pms$y.text.col <- risk.table.y.text.col + pms$fontsize <- risk.table.fontsize + pms$survtable <- "risk.table" + # color risk.table ticks by strata + if(risk.table.y.text.col) pms$y.text.col <- scurve_cols + res$table <- risktable <- do.call(ggsurvtable_custom, pms) + } + + # Add the cumulative number of events + + if(cumevents){ + pms$color <- cumevents.col + pms$title <- cumevents.title + pms$y.text <- cumevents.y.text + if(cumevents.y.text.col) pms$y.text.col <- scurve_cols + pms$fontsize <- fontsize + pms$survtable <- "cumevents" + res$cumevents <- do.call(ggsurvtable, pms) + } + + # Add ncensor.plot or cumcensor plot + #%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% + if(ncensor.plot){ + ncensor_plot <- ggplot(d, aes_string("time", "n.censor")) + + ggpubr::geom_exec(geom_bar, d, color = surv.color, fill = surv.color, + stat = "identity", position = "dodge")+ + coord_cartesian(xlim = xlim)+ + scale_y_continuous(breaks = sort(unique(d$n.censor))) + + ggtheme + + ncensor_plot <- ggpubr::ggpar(ncensor_plot, palette = pms$palette) + ncensor_plot <- ncensor_plot + ggplot2::labs(color = pms$legend.title, fill = pms$legend.title, + x = xlab, y = "n.censor", title = ncensor.plot.title) + + # For backward compatibility + ncensor_plot <- .set_general_gpar(ncensor_plot, ...) # general graphical parameters + ncensor_plot <- .set_ncensorplot_gpar(ncensor_plot, ...) # specific graphical params + ncensor_plot <- ncensor_plot + tables.theme + + if(!pms$xlog) ncensor_plot <- ncensor_plot + scale_x_continuous(breaks = pms$time.breaks, + labels = pms$xticklabels, expand = .expand) + else ncensor_plot <- ncensor_plot + ggplot2::scale_x_continuous(breaks = pms$time.breaks, trans = "log10", labels = pms$xticklabels) + + } + else if(cumcensor){ + pms$color <- cumcensor.col + pms$title <- cumcensor.title + if(cumcensor.y.text.col) pms$y.text.col <- scurve_cols + #pms$y.text.col <- cumcensor.y.text.col + pms$fontsize <- fontsize + pms$survtable <- "cumcensor" + ncensor_plot <- do.call(ggsurvtable, pms) + } + if(ncensor.plot | cumcensor) + res$ncensor.plot <- ncensor_plot + + + # Defining attributs for ggsurvplot + #:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: + heights <- list( + plot = surv.plot.height, + table = ifelse(risk.table, risk.table.height, 0), + ncensor.plot = ifelse(ncensor.plot | cumcensor, ncensor.plot.height, 0), + cumevents = ifelse(cumevents, cumevents.height, 0) + ) + y.text <- list( + table = risk.table.y.text, + cumevents = cumevents.y.text, + cumcensor = cumcensor.y.text + ) + y.text.col <- list( + table = risk.table.y.text.col, + cumevents = cumevents.y.text.col, + cumcensor = cumcensor.y.text.col + ) + + + class(res) <- c("ggsurvplot", "ggsurv", "list") + attr(res, "heights") <- heights + attr(res, "y.text") <- y.text + attr(res, "y.text.col") <- y.text.col + attr(res, "legend.position") <- legend + attr(res, "legend.labs") <- legend.labs + attr(res, "cumcensor") <- cumcensor + attr(res, "risk.table.pos") <- risk.table.pos + attr(res, "axes.offset") <- axes.offset + res +} + + +# Parse risk.table argument +#%%%%%%%%%%%%%%%%%%%%%%% +# risk.table a logical value (TRUE/FALSE) or a string ("absolute", "percentage", "abs_pct") +.parse_risk_table_arg <- function(risk.table){ + res <- list(display = risk.table, type = "absolute") + if(inherits(risk.table, "character") ){ + if(risk.table %in% c("absolute", "percentage", "abs_pct", "nrisk_cumcensor", "nrisk_cumevents") ) + res <- list(display = TRUE, type = risk.table) + else stop("Allowed values for risk.table are: TRUE, FALSE, 'absolute', 'percentage', 'nrisk_cumcensor', 'nrisk_cumevents' ") + } + res +} + + +# Check if fun is cloglog +.is_cloglog <- function(fun){ + res <- FALSE + if(is.character(fun)){ + res <- fun == "cloglog" + } + res +} + diff --git a/PioneerWatchfulWaiting/ui.R b/PioneerWatchfulWaiting/ui.R index 23e3da49..72f26aa3 100644 --- a/PioneerWatchfulWaiting/ui.R +++ b/PioneerWatchfulWaiting/ui.R @@ -42,6 +42,7 @@ dashboardPage( if (exists("cohortCount")) addInfo(menuItem("Cohort Counts", tabName = "cohortCounts"), "cohortCountsInfo"), if (exists("covariateValue")) addInfo(menuItem("Cohort Characterization", tabName = "cohortCharacterization"), "cohortCharacterizationInfo"), if (exists("cohortTimeToEvent")) addInfo(menuItem("Time To Event", tabName = "timeToEvent"), "cohortCountsInfo"), + if (exists("metricsDistribution")) addInfo(menuItem("Metrics Distribution", tabName = "metricsDistribution"), "cohortsCountsInfo"), if (exists("covariateValue")) addInfo(menuItem("Compare Cohort Char.", tabName = "compareCohortCharacterization"), "compareCohortCharacterizationInfo"), menuItem("Database information", tabName = "databaseInformation"), menuItem("Change Log", tabName="changeLog"), @@ -70,24 +71,47 @@ dashboardPage( ), conditionalPanel(condition = "input.tabs=='timeToEvent'", - shinyWidgets::pickerInput("databasesTimeToEvent", "Database", - choices = database$databaseId, - selected = database$databaseId, - options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), - multiple = FALSE), - shinyWidgets::pickerInput("targetTimeToEvent", "Cohort", - choices = targetCohort$targetName, - selected = 'All', - options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), - multiple = FALSE), - shinyWidgets::pickerInput("strataTimeToEvent", "Strata", - choices = strataCohort$strataName, - selected = 'All', - options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), - multiple = FALSE) + shinyWidgets::pickerInput("databasesTimeToEvent", "Database", + choices = database$databaseId, + selected = database$databaseId, + options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), + multiple = FALSE), + shinyWidgets::pickerInput("targetTimeToEvent", "Cohort", + choices = targetCohort$targetName, + selected = 'All', + options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), + multiple = FALSE), + shinyWidgets::pickerInput("strataTimeToEvent", "Strata", + choices = strataCohort$strataName, + selected = 'All', + options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), + multiple = FALSE), + shinyWidgets::pickerInput("KMPlot", "Plot Choice", + choices = KMIds$name, + selected = KMIds$name, + options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), + multiple = TRUE ) + ), + + conditionalPanel(condition = "input.tabs=='metricsDistribution'", + shinyWidgets::pickerInput("databasesMetricsDistribution", "Database", + choices = database$databaseId, + selected = database$databaseId, + options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), + multiple = FALSE), + shinyWidgets::pickerInput("targetMetricsDistribution", "Cohort", + choices = targetCohort$targetName, + selected = 'All', + options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), + multiple = FALSE), + shinyWidgets::pickerInput("strataMetricsDistribution", "Strata", + choices = strataCohort$strataName, + selected = 'All', + options = shinyWidgets::pickerOptions(actionsBox = TRUE, liveSearch = TRUE, dropupAuto = FALSE), + multiple = FALSE) ), - conditionalPanel(condition = "input.tabs!='about' & input.tabs!='cohorts' & input.tabs!='cohortCounts' & input.tabs!='timeToEvent' & input.tabs!='databaseInformation' & input.tabs!='changeLog'" , + conditionalPanel(condition = "input.tabs!='about' & input.tabs!='cohorts' & input.tabs!='cohortCounts' & input.tabs!='timeToEvent' & input.tabs!='metricsDistribution' & input.tabs!='databaseInformation' & input.tabs!='changeLog'" , shinyWidgets::pickerInput("targetCohort", "Cohort (Target)", choices = characterizationTargetCohort$targetName, selected = targetName, @@ -185,6 +209,8 @@ dashboardPage( ), tabItem(tabName = "timeToEvent", + div(class="download-container", + downloadButton("dlTimeToEvent", "Download Data")), tags$h4(textOutput('survivalHeader')), tags$div( plotOutput("TimeToEventDeath", height = 650, width = 1050) @@ -192,6 +218,12 @@ dashboardPage( ), + tabItem (tabName = "metricsDistribution", + tags$h4(textOutput('metricsHeader')), + # htmlOutput("borderCharacterization"), + dataTableOutput("metricsTable") + ), + tabItem(tabName = "compareCohortCharacterization", htmlOutput("comparisonName"), downloadButton("dlCharCompare", "Download Data"), diff --git a/PioneerWatchfulWaiting/utilities.R b/PioneerWatchfulWaiting/utilities.R new file mode 100644 index 00000000..0e64eee0 --- /dev/null +++ b/PioneerWatchfulWaiting/utilities.R @@ -0,0 +1,491 @@ + + +# Count the number of ggplots in a list +.count_ggplots <- function(list.objects){ + nplot <- 0 + for(i in 1:length(list.objects)){ + if(is.ggplot(list.objects[[i]])) nplot <- nplot +1 + } + nplot +} + +# Extract legend from a ggplot +.get_legend <- function(myggplot){ + tmp <- ggplot2::ggplot_gtable(ggplot2::ggplot_build(myggplot)) + leg <- which(sapply(tmp$grobs, function(x) x$name) == "guide-box") + if(length(leg) > 0) leg <- tmp$grobs[[leg]] # if legend + else leg <- NULL + return(leg) +} + +# Connect observations by stairs. +# %%%%%%%%%%%%%%%%%%%%%%%%%%%%% +# Connect observations by stairs. +# +# mapping the aesthetic mapping +# data a layer specific dataset +# stat the statistical transformation to use on the data for this layer +# position the position adjustment to use for overlapping points on this layer +# na.rm logical frag whether silently remove missing values +# ... other arguments passed to methods +.geom_confint <- function (mapping = NULL, data = NULL, stat = "identity", + position = "identity", na.rm = FALSE, ...) { + ggplot2::layer(mapping = mapping, + data = data, + stat = stat, + geom = GeomConfint, + position = position, + params = list(na.rm = na.rm, ...)) +} +GeomConfint <- ggplot2::ggproto('GeomConfint', ggplot2::GeomRibbon, + required_aes = c("x", "ymin", "ymax"), + draw_group = function(self, data, panel_scales, coord, na.rm = FALSE) { + if (na.rm) data <- data[stats::complete.cases(self$required_aes), ] + data <- data[order(data$group, data$x), ] + data <- self$stairstep_confint(data) + ggplot2:::GeomRibbon$draw_group(data, panel_scales, coord, na.rm = na.rm) + }, + stairstep_confint = function (data) { + data <- as.data.frame(data)[order(data$x), ] + n <- nrow(data) + ys <- rep(1:n, each = 2)[-2 * n] + xs <- c(1, rep(2:n, each = 2)) + data.frame(x = data$x[xs], ymin = data$ymin[ys], ymax = data$ymax[ys], + data[xs, setdiff(names(data), c("x", "ymin", "ymax"))]) + } +) + +GeomConfint_old <- ggplot2::ggproto('GeomConfint_old', ggplot2::GeomRibbon, + required_aes = c("x", "ymin", "ymax"), + draw_group = function(data, panel_scales, coord, na.rm = FALSE) { + if (na.rm) data <- data[complete.cases(data[c("x", "ymin", "ymax")]), ] + data <- rbind(data, data) + data <- data[order(data$x), ] + data$x <- c(data$x[2:nrow(data)], NA) + data <- data[complete.cases(data["x"]), ] + GeomRibbon$draw_group(data, panel_scales, coord, na.rm = FALSE) + } +) + + +# Remove NULL items in a vector or list +# +# x a vector or list +.compact <- function(x){Filter(Negate(is.null), x)} + +# remove white space at the head and the tail of a string +.trim <- function(x){gsub("^\\s+|\\s+$", "", x)} + +# Take a data frame and return a flatten value +.flat <- function(x){ + if(is.null(x)) return(NA) + x <- as.data.frame(x) + x <- tidyr::gather_(x, + key_col = "key", value_col = "value", + gather_cols = colnames(x)) + x$value +} + +# extract dataset if not provided +.get_data <- function(fit, data = NULL, complain = TRUE) { + if(is.null(data)){ + if (complain) + warning ("The `data` argument is not provided. Data will be extracted from model fit.") + data <- eval(fit$call$data) + if (is.null(data)) + stop("The `data` argument should be provided either to ggsurvfit or survfit.") + } + data +} + +# Compute default axis breaks as ggplot2 +#------------------------------------- +# Return a vector of axis labels +.get_default_breaks <- function(x, .log = FALSE){ + if(!.log) scales::extended_breaks()(x) + else scales::log_breaks()(x) +} + + +# Get survival summary for a specified time points +#------------------------------------------------ +# fit: survfit object +# data: data used for survfit +# times: a vector of timepoints +# +# Return a data frame with the following components: +# - strata: stratification of curve estimation +# - time: the timepoints on the curve +# - n.risk: the number of subjects at risk at time t-0 +# - n.event: the cumulative number of events that have occurred since the last time listed until time t+0 +# - n.censor: number of censored subjects +# - strata_size: number of subject in the strata +.get_timepoints_survsummary <- function(fit, data, times, decimal.place = 0) +{ + survsummary <- summary(fit, times = times, extend = TRUE) + + + if (is.null(fit$strata)) { + .strata <- factor(rep("All", length(survsummary$time))) + strata_names <- "All" + strata_size <- rep(fit$n, length(.strata)) + } + else { + fit <- dplyr::mutate(dplyr::group_by(fit,strata), cum.n.censor=cumsum(n.censor)) + n <- aggregate(fit$n.risk, by=list(fit$strata), max) + strata <- unique(fit$strata) + strata_names <- as.character(unique(fit$strata)) + nstrata <- length(strata_names) + nstrata_size <- rep(n$x, each = length(strata)/nstrata) + + } + + res <- data.frame() + for (st in strata){ + for (time in times){ + row <- fit[fit$time >= time & fit$strata == st, c('strata', 'n.risk', 'cum.n.censor')][1,] + if (is.na(row[[1]]) & max(times) == time){ + row <- tail(fit[fit$time <= time & fit$strata == st, c('strata', 'n.risk', 'cum.n.censor')], 1) + } + row$time <- time + res <- rbind(res, row) + } + } + + rownames(res) <- 1:nrow(res) + res +} + +# Get variable names in strata +# ----------------------------------------- +# strata: a vector +# fit: survfit object +# data: data used to fit survival curves +.get_variables <- function(strata, fit, data = NULL){ + variables <- sapply(as.vector(strata), + function(x){ + x <- unlist(strsplit(x, "=|,\\s+", perl=TRUE)) + x[seq(1, length(x), 2)] + }) + variables <- unique(as.vector(variables)) + variables <- intersect(variables, colnames(.get_data(fit, data) )) + variables +} + +# levels of a given variable used in survfit formula +# ---------------------------- +# variable: variable name +.get_variable_value <- function(variable, strata, fit, data = NULL){ + res <- sapply(as.vector(strata), function(x){ + x <- unlist(strsplit(x, "=|(\\s+)?,\\s+", perl=TRUE)) + # When a factor name is the same as one of its level, index is of length 2 + index <- grep(paste0("^", variable, "$"), x)[1] + .trim(x[index+1]) + }) + res <- as.vector(res) + var_levels <- levels(.get_data(fit, data)[, variable]) + if(!is.null(var_levels)) res <- factor(res, levels = var_levels) + else res <- as.factor(res) + res +} + + +# remove dollar sign ($) in strata +# --------------------------------- +# remove dollar sign ($) in strata, in the situation, where +# the user uses data$variable to fit survival curves +.clean_strata <- function(strata, fit){ + is_dollar_sign <- grepl("$", as.character(strata)[1], fixed=TRUE) + if(is_dollar_sign) { + strata <- as.character(strata) + data_name <- unlist(strsplit(strata[1], "$", fixed =TRUE))[1] + strata <- gsub(paste0(data_name, "$"), "", strata, fixed=TRUE) + strata <- as.factor(strata) + } + else if(!missing(fit)) strata <- factor(strata, levels = names(fit$strata)) + return(strata) +} + + +# Set large dash as y tick labels when ytext = FALSE +# Each dash corresponds to a strata +# This is used for tables under the main survival plots +# +.set_large_dash_as_ytext <- function(ggp){ + ggp + theme(axis.text.y = ggtext::element_markdown(size = 50, vjust = 0.5), + axis.ticks.y = element_blank()) +} + + +# Transform x-axis labels according to the scale see ggsurvplot(). +# +# labels: numeric vector (x-axis labels) +#xscale: numeric or character values (see +# gsurvplot). If numeric, the value is used to divide the labels on the x axis. +# For example, a value of 365.25 will give labels in years instead of the +# original days. If character, allowed options include one of c("d_m", "d_y", +# "m_d", "m_y", "y_d", "y_m"), where d = days, m = months and y = years. For +# example, xscale = "d_m" will transform labels from days to months; xscale = +# "m_y", will transform labels from months to years. +.format_xticklabels <- function(labels, xscale){ + + # 1 year = 365.25 days + # 1 month = 365.25/12 = 30.4375 days + if(is.numeric(xscale)) xtrans <- 1/xscale + else + xtrans <- switch(xscale, + d_m = 12/365.25, + d_y = 1/365.25, + m_d = 365.25/12, + m_y = 1/12, + y_d = 365.25, + y_m = 12, + 1 + ) + round(labels*xtrans,2) +} + + +# Extract strata colors used in survival curves +# Will be used to color the y.text of risk table and cumevents table +.extract_ggplot_colors <- function(p, grp.levels){ + g <- ggplot2::ggplot_build(p) + .cols <- unlist(unique(g$data[[1]]["colour"])) + if(!is.null(grp.levels)){ + if(length(.cols)==1) .cols <- rep(.cols, length(grp.levels)) + names(.cols) <- grp.levels + } + .cols +} + +#%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% +# Helper functions for survival curves +#%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% + +.is_survfit <- function(fit){ + inherits(fit, "survfit") +} + +.is_grouped_data <- function(data){ + inherits(data, c("surv_group_by")) +} + +.get_fit_formula <- function(fit){ + fit$call$formula %>% + stats::as.formula() +} + +.build_formula <- function(surv.obj, variables){ + . <- NULL + paste(variables, collapse = " + ") %>% + paste0(surv.obj, " ~ ", .) %>% + stats::as.formula() +} + +# Function defining a transformation of the survival curve +#:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: +# see ?survival::plot.survfit +# d: data frame containing the column surv, upper and lower +# fun the function +.apply_surv_func <- function(d, fun = NULL){ + + if (!is.null(fun)) { + if (is.character(fun)) { + fun <- switch(fun, log = function(y) log(y), + event = function(y) 1 - y, + cumhaz = function(y) -log(y), + cloglog = function(y) log(-log(y)), + pct = function(y) y * 100, + logpct = function(y) 100 * y, + identity = function(y) y, + stop("Unrecognized survival function argument")) + } + else if (!is.function(fun)) { + stop("Invalid 'fun' argument") + } + cnames <- colnames(d) + if("surv" %in% cnames) d$surv <- fun(d$surv) + if("upper" %in% cnames) d$upper <- fun(d$upper) + if("lower" %in% cnames) d$lower <- fun(d$lower) + } + return(d) +} + + +# Get the names of formulas +#......................................................................... +# If formulas is a named lists, returns the list names if available. +# If formula names are not available, collapse the variables in the formula, and use this as the formula name +# If formula is a formula object, returns collapsed variable names using "+" +.get_formula_names <- function(formula){ + + # helper function to return collapsed variable names for one formula. + .fname <- function(formula){ + res <- attr(stats::terms(formula), "term.labels") + if(.is_empty(res)) res <- "null_model" + else res <- .collapse(res, sep = " + ") + res + } + + if(.is_list(formula)){ + fnames <- names(formula) + if(is.null(fnames)) fnames <- purrr::map(formula, .fname) %>% + unlist() + } + + else fnames <- .fname(formula) + fnames +} + + + +# Get the names of fit +# If fit is a named lists, returns the list names if available. +# If fit names are not available, collapse the variables in the formula, and use this as the fit name +#......................................................................... +.get_fit_names <- function(fit){ + + if(.is_list(fit)){ + fnames <- names(fit) + if(is.null(fnames)) { + fnames <- purrr::map(fit, .get_fit_formula) %>% + .get_formula_names() + } + } + else fnames <- .get_fit_formula(fit) %>% + .get_formula_names() + fnames +} + + +# Extract survfit components +#................................................................................. +# Return a list: list(formula, surv, variables, data.all, data.formula) +# - formula: survival formula +# - surv: surv object +# - variables: vector of variable names +# - data.all: the dataset used in survfit +# - data.formula: data off all variables in the formula including time and status +.extract.survfit <- function(fit, data = NULL){ + + if(inherits(fit, c("survfit.cox", "survfitcox"))) + return(list()) + + .formula <- fit$call$formula %>% + stats::as.formula() + surv.obj <- deparse(.formula[[2]]) + surv.vars <- attr(stats::terms(.formula), "term.labels") + data.all <- data <- .get_data(fit, data = data, complain = FALSE) + # data of variables used in formula + data.formula <- stats::get_all_vars(.formula, data = data) #%>% + #na.omit() + + list(formula = .formula, surv = surv.obj, + variables = surv.vars, + data.all = data.all, + data.formula = data.formula) +} + + +# Create strata from variable names +#................................................................................. +# Returns a factor +# Example: +# library(survival) +# .create_strata(colon, c("sex", "rx")) +.create_strata <- function(data, var.names, sep = ", "){ + + # Strata + .strata <- data[, var.names, drop = FALSE] %>% + survival::strata(sep = sep) + .strata.levels <- levels(.strata) + # Replace "=" by ". + .strata <- gsub("=", ":", .strata) %>% .trim() + .strata.levels <- gsub("=", ":", .strata.levels) %>% .trim() + factor(.strata, levels = .strata.levels) +} + + + +#%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% +# General helper functions +#%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% + +# Returns the levels of a factor variable +#::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: +.levels <- function(x){ + if(!is.factor(x)) x <- as.factor(x) + levels(x) +} + +# Check if is a list +#::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: +.is_list <- function(x){ + inherits(x, c("list", "vctrs_list_of")) +} + +# Collapse one or two vectors +#::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: +.collapse <- function(x, y = NULL, sep = "."){ + if(missing(y)) + paste(x, collapse = sep) + else if(is.null(x) & is.null(y)) + return(NULL) + else if(is.null(x)) + return (as.character(y)) + else if(is.null(y)) + return(as.character(x)) + else + paste0(x, sep, y) +} + +# Check if en object is empty +#::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: +.is_empty <- function(x){ + length(x) == 0 +} + + +# Pasting the column name to each value of a dataframe +#::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: +.paste_colnames <- function(data, sep = "."){ + + data <- as.data.frame(data) + + if(ncol(data) == 1){ + + res <- paste0(colnames(data), ".", data[[1]]) + res <- data.frame(x = res, stringsAsFactors = FALSE) + colnames(res) <- colnames(data) + return(res) + } + + res <- apply(data, 1, + function(row, cname){paste(cname, row, sep = sep)}, + colnames(data) + ) %>% + t() %>% + as.data.frame(stringsAsFactors = FALSE) + colnames(res) <- colnames(data) + res +} + + +# Bind data list by rows +#::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: +# add id columns for a named data list +.rbind_data_list <- function(df.list){ + + .names <- names(df.list) + + if(!is.null(.names)){ + df.list <- purrr::map2(df.list, .names, function(df, .name){ + dplyr::mutate(df, id = .name) + }) + } + + id <- NULL + res <- dplyr::bind_rows(df.list) %>% + dplyr::select(id, dplyr::everything()) + res +}