diff --git a/tox.ini b/tox.ini
index 229f755..3534f1c 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,5 +1,5 @@
 [tox]
-envlist = py38,py39,py310,lint
+envlist = py310,lint
 requires = tox-conda
 
 [testenv]
@@ -7,7 +7,7 @@ setenv =
     CONDA_DLL_SEARCH_MODIFICATION_ENABLE = 1
 whitelist_externals = python
 
-[testenv:py{38,39,310}]
+[testenv:py{310}]
 conda_deps =
     pytest
     rdkit