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Genetic Analysis of Population-based Association Studies Informatics Guide 2024

Software/Tools used during the course

Software Version (if not latest) Module Notes
R Programming Language 4.4.1 Module Name -
R package ISwR 2.0-8 Module Name Depends on R (≥ 2.6.0)
R package TwoSampleMR v0.3.2. Module Name -
R package MRInstruments 0.3.2 Module Name -
R package RadialMR 1.1 Module Name -
R package MendelianRandomization 0.10.0 Module Name Depends on R (≥ 3.0.1)
Perl 5.40 Module Name GitHub Repo
Python Programming Language 5.10.1+ Module Name -
VCFtools 3.0 Module Name GitHub Repo
BCFtools 1.4.1 Module Name -
SNPTEST 2.5.2 Module Name -
META 1.7 Module Name -
Plink 1.9 Module Name Documentaion
GCTA 1.9.1 beta1 Module Name Documentaion
FaST-LMMl 2.07 Module Name Documentaion
SHAPEIT2 Version Details Module Name Documentaion
IMPUTE2 Version Details Module Name Documentaion
SAIGE 1.0.0 Module Name -

Informatics Set-Up

We are currently using Oracle VM Virtual Box (https://www.virtualbox.org/) to deliver Informatics, you can find Virtual Box Guides below: Virtual Machine SetUp Guide for Intel-Mac and Windows.

The Host OS Requirements for Virtual Box

  • RAM requirement: 8GB (preferably 12GB)
  • Processor requirement: 4 processors (preferably 8)
  • Hard disk space: 200GB
  • Admin rights to the computer

Note: Please be aware that Virtual Box is currently incompatible with M1/M2/M3 chips on MacBook. It is exclusively designed for use on Intel-based MacBooks. The current version in use is Virtual Box 7.0.

Citing and Re-using Course Material

The course data are free to reuse and adapt with appropriate attribution. All course data in these repositories are licensed under the Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). Creative Commons Licence

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