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PhenoMapping is a computational framework that provides some workflows and methodologies for the understanding of mechanisms underlying phenotypes using genome-scale models (GEMs). PhenoMapping classifies the information in a GEM as organism-specific information and context-specific information. Organism-specific information includes the (i) bio…

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PhenoMapping

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PhenoMapping: A workflow to decompose the information in genome-scale models into modules that allow the study of cellular mechanisms underlying phenotypes

This code is the release for the study of context-specific information applied to analyse high-throughput gene knockout data in the blood and liver stage development of the malaria parasite P. berghei

You will need matTFA to run it and TEX-FBA to perform the transcriptomics related analyses. We recommend using commercial solvers such as CPLEX to run these problems.

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PhenoMapping is a computational framework that provides some workflows and methodologies for the understanding of mechanisms underlying phenotypes using genome-scale models (GEMs). PhenoMapping classifies the information in a GEM as organism-specific information and context-specific information. Organism-specific information includes the (i) bio…

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