diff --git a/recipes/pyopenms/meta.yaml b/recipes/pyopenms/meta.yaml
index d19b3b6f74295..f23aa6d2717e9 100644
--- a/recipes/pyopenms/meta.yaml
+++ b/recipes/pyopenms/meta.yaml
@@ -16,7 +16,8 @@ source:
 {% endif %}
 
 build:
-  number: 4
+  number: 5
+  skip: True  # [osx]
   run_exports:
     - {{ pin_subpackage("pyopenms", max_pin="x.x") }}