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mutations tab shows intergenic SV as intragenic #11294

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tmazor opened this issue Dec 18, 2024 · 1 comment
Open

mutations tab shows intergenic SV as intragenic #11294

tmazor opened this issue Dec 18, 2024 · 1 comment

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@tmazor
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tmazor commented Dec 18, 2024

On the mutations tab, the protein change column shows this event as intragenic:
image
https://genie.cbioportal.org/results/mutations?cancer_study_list=genie_public&tab_index=tab_visualize&case_set_id=-1&Action=Submit&gene_list=ATM&Z_SCORE_THRESHOLD=2.0&RPPA_SCORE_THRESHOLD=2.0&profileFilter=mutations%2Cstructural_variants%2Ccna&case_ids=genie_public%3AGENIE-DFCI-002365-6793&geneset_list=%20

But on the patient page, oncopanel and structural variants page, it's clearly an intergenic event:
image
https://genie.cbioportal.org/patient?sampleId=GENIE-DFCI-002365-6793&studyId=genie_public

image image

The mutations tab needs to also display this as an intergenic event.

@Swayam-code
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Swayam-code commented Jan 2, 2025

Hey @tmazor , I can take this issue. The problem is that the mutations tab is showing an intergenic event as "intragenic," while other pages (like the patient page and structural variants page) correctly display it as "intergenic."

I'll investigate the data pipeline and ensure that the mutations tab reflects the correct event classification by leveraging the same logic and annotations as the structural variants page. This will involve verifying the source of annotations, updating the rendering logic in the mutations tab, and validating consistency across all affected views.

Can you assign this issue to me?

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