diff --git a/front_end/models/react_native/ReactDevToolsBindingsModel.ts b/front_end/models/react_native/ReactDevToolsBindingsModel.ts
index e3cc309367e..59a57b18d7c 100644
--- a/front_end/models/react_native/ReactDevToolsBindingsModel.ts
+++ b/front_end/models/react_native/ReactDevToolsBindingsModel.ts
@@ -40,6 +40,18 @@ export class ReactDevToolsBindingsModel extends SDK.SDKModel.SDKModel {
   private fuseboxDispatcherIsInitialized = false;
   private readonly domainToMessageQueue: Map<DomainName, Array<JSONValue>> = new Map();
 
+  override dispose(): void {
+    this.domainToListeners.clear();
+    this.domainToMessageQueue.clear();
+
+    const runtimeModel = this.target().model(SDK.RuntimeModel.RuntimeModel);
+    runtimeModel?.removeEventListener(SDK.RuntimeModel.Events.BindingCalled, this.bindingCalled, this);
+    runtimeModel?.removeEventListener(
+        SDK.RuntimeModel.Events.ExecutionContextCreated, this.onExecutionContextCreated, this);
+    runtimeModel?.removeEventListener(
+        SDK.RuntimeModel.Events.ExecutionContextDestroyed, this.onExecutionContextDestroyed, this);
+  }
+
   private bindingCalled(event: BindingCalledEventTargetEvent): void {
     // If binding name is not initialized, then we failed to get its name
     if (this.messagingBindingName === null || event.data.name !== this.messagingBindingName) {
diff --git a/front_end/panels/react_devtools/ReactDevToolsModel.ts b/front_end/panels/react_devtools/ReactDevToolsModel.ts
index 772d2be45da..d964d931203 100644
--- a/front_end/panels/react_devtools/ReactDevToolsModel.ts
+++ b/front_end/panels/react_devtools/ReactDevToolsModel.ts
@@ -77,7 +77,34 @@ export class ReactDevToolsModel extends SDK.SDKModel.SDKModel<EventTypes> {
     );
 
     // Notify backend if Chrome DevTools was closed, marking frontend as disconnected
-    window.addEventListener('beforeunload', () => this.#bridge?.shutdown());
+    window.addEventListener('beforeunload', this.#handleBeforeUnload);
+  }
+
+  override dispose(): void {
+    this.#bridge?.removeListener('reloadAppForProfiling', this.#handleReloadAppForProfiling);
+    this.#bridge?.shutdown();
+
+    this.#bindingsModel.removeEventListener(
+        ReactNativeModels.ReactDevToolsBindingsModel.Events.BackendExecutionContextCreated,
+        this.#handleBackendExecutionContextCreated,
+        this,
+    );
+    this.#bindingsModel.removeEventListener(
+        ReactNativeModels.ReactDevToolsBindingsModel.Events.BackendExecutionContextUnavailable,
+        this.#handleBackendExecutionContextUnavailable,
+        this,
+    );
+    this.#bindingsModel.removeEventListener(
+        ReactNativeModels.ReactDevToolsBindingsModel.Events.BackendExecutionContextDestroyed,
+        this.#handleBackendExecutionContextDestroyed,
+        this,
+    );
+
+    window.removeEventListener('beforeunload', this.#handleBeforeUnload);
+
+    this.#bridge = null;
+    this.#store = null;
+    this.#listeners.clear();
   }
 
   override dispose(): void {
@@ -151,6 +178,10 @@ export class ReactDevToolsModel extends SDK.SDKModel.SDKModel<EventTypes> {
     return rdtBindingsModel.sendMessage(ReactDevToolsModel.FUSEBOX_BINDING_NAMESPACE, message);
   }
 
+  #handleBeforeUnload = (): void => {
+    this.#bridge?.shutdown();
+  };
+
   #handleBackendExecutionContextCreated(): void {
     const rdtBindingsModel = this.#bindingsModel;
     if (!rdtBindingsModel) {