From d92daf8918dd6bfdc54ff63acf7d7797002df014 Mon Sep 17 00:00:00 2001 From: Raymond Lee Date: Mon, 27 Jan 2025 16:18:32 -0800 Subject: [PATCH] Add has_part relation; #29515 --- src/ontology/go-edit.obo | 103 ++++++++++++++++++++------------------- 1 file changed, 52 insertions(+), 51 deletions(-) diff --git a/src/ontology/go-edit.obo b/src/ontology/go-edit.obo index 611fea1d5..7007436ce 100644 --- a/src/ontology/go-edit.obo +++ b/src/ontology/go-edit.obo @@ -15440,7 +15440,7 @@ namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:0000150 ! glandular epithelial cell +intersection_of: results_in_acquisition_of_features_of CL:0000150 ! glandular secretory epithelial cell [Term] id: GO:0002068 @@ -15449,7 +15449,7 @@ namespace: biological_process def: "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0032502 ! developmental process -intersection_of: results_in_development_of CL:0000150 ! glandular epithelial cell +intersection_of: results_in_development_of CL:0000150 ! glandular secretory epithelial cell relationship: part_of GO:0002067 ! glandular epithelial cell differentiation [Term] @@ -15479,7 +15479,7 @@ namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation -intersection_of: results_in_maturation_of CL:0000150 ! glandular epithelial cell +intersection_of: results_in_maturation_of CL:0000150 ! glandular secretory epithelial cell relationship: part_of GO:0002068 ! glandular epithelial cell development [Term] @@ -28374,7 +28374,7 @@ def: "The process in which an amino acid is transported across a membrane." [GOC comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "amino acid membrane transport" EXACT [] intersection_of: GO:0055085 ! transmembrane transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion created_by: dph creation_date: 2009-11-02T02:36:11Z @@ -51108,7 +51108,7 @@ synonym: "cation/amino acid symporter" BROAD [] synonym: "hydrogen:amino acid symporter activity" EXACT [] intersection_of: GO:0015293 ! symporter activity intersection_of: has_primary_input CHEBI:15378 ! hydron -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion [Term] id: GO:0005281 @@ -51141,7 +51141,7 @@ synonym: "sodium:amino acid transporter activity" BROAD [] synonym: "threonine/serine:sodium symporter activity" NARROW [] intersection_of: GO:0015293 ! symporter activity intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion [Term] id: GO:0005287 @@ -52162,7 +52162,7 @@ synonym: "cation/amino acid symporter activity" EXACT [] synonym: "cation:amino acid symporter activity" EXACT [] intersection_of: GO:0015293 ! symporter activity intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] @@ -62914,7 +62914,7 @@ synonym: "cellular amino acid metabolic process" EXACT [] synonym: "cellular amino acid metabolism" EXACT [] is_a: GO:0044238 ! primary metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input_or_output CHEBI:35238 ! amino-acid zwitterion property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] @@ -63614,7 +63614,7 @@ synonym: "cellular modified amino acid metabolic process" EXACT [GOC:mah] synonym: "cellular modified amino acid metabolism" EXACT [GOC:mah] synonym: "modified amino acid metabolism" EXACT [GOC:mah] intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_input_or_output CHEBI:83821 ! amino-acid derivative property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] @@ -66772,7 +66772,7 @@ def: "The directed movement of amino acids, organic acids containing one or more subset: goslim_pir subset: goslim_yeast intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion [Term] id: GO:0006867 @@ -81283,7 +81283,7 @@ synonym: "amino acid synthesis" EXACT [] synonym: "cellular amino acid biosynthetic process" EXACT [] xref: Wikipedia:Amino_acid_synthesis intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_output CHEBI:35238 ! amino-acid zwitterion property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27304" xsd:anyURI @@ -87117,7 +87117,7 @@ synonym: "amino acid catabolism" EXACT [] synonym: "amino acid degradation" EXACT [] synonym: "cellular amino acid catabolic process" EXACT [] intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] @@ -110272,7 +110272,7 @@ synonym: "amino acid/choline transmembrane transporter activity" NARROW [] synonym: "general amino acid permease activity" RELATED [] synonym: "hydroxy/aromatic amino acid permease activity" RELATED [] intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion relationship: part_of GO:0003333 {source="GO_REF:0000090"} ! amino acid transmembrane transport [Term] @@ -112701,7 +112701,7 @@ synonym: "amino acid-transporting ATPase activity" EXACT [] synonym: "ATP-dependent amino acid transmembrane transporter activity" EXACT [] synonym: "ATPase-coupled amino acid transmembrane transporter activity" RELATED [] intersection_of: GO:0140359 ! ABC-type transporter activity -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion relationship: part_of GO:0003333 ! amino acid transmembrane transport [Term] @@ -115625,7 +115625,7 @@ namespace: biological_process def: "The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:krc] synonym: "tartrate transport" RELATED [] intersection_of: GO:0055085 ! transmembrane transport -intersection_of: has_primary_input CHEBI:35397 ! tartrate(1-) +intersection_of: has_primary_input CHEBI:35397 ! DL-tartrate(1-) [Term] id: GO:0015746 @@ -123241,7 +123241,7 @@ def: "Binding to an amino acid, organic acids containing one or more amino subst subset: goslim_metagenomics subset: goslim_pir intersection_of: GO:0005488 ! binding -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion [Term] id: GO:0016598 @@ -127320,7 +127320,7 @@ def: "Enables the transfer of a solute or solutes from one side of a membrane to synonym: "potassium:amino acid symporter activity" EXACT [] intersection_of: GO:0015293 ! symporter activity intersection_of: has_primary_input CHEBI:29103 ! potassium(1+) -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion [Term] id: GO:0017038 @@ -188313,7 +188313,7 @@ synonym: "amino acid efflux" EXACT [] synonym: "amino acid export" BROAD [] synonym: "amino acid transmembrane export" BROAD [] intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion intersection_of: has_target_end_location GO:0005576 ! extracellular region intersection_of: has_target_start_location GO:0005829 ! cytosol intersection_of: results_in_transport_across GO:0005886 ! plasma membrane @@ -188328,7 +188328,7 @@ def: "The directed movement of amino acids out of the vacuole, across the vacuol synonym: "amino acid efflux from vacuole" EXACT [] synonym: "vacuolar amino acid export" EXACT [] intersection_of: GO:0055085 ! transmembrane transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion intersection_of: has_target_end_location GO:0005829 ! cytosol intersection_of: has_target_start_location GO:0005775 ! vacuolar lumen @@ -188339,7 +188339,7 @@ namespace: biological_process def: "The directed movement of amino acids into the vacuole across the vacuolar membrane." [GOC:mah] synonym: "vacuolar amino acid import" EXACT [] intersection_of: GO:0055085 ! transmembrane transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion intersection_of: has_target_end_location GO:0005775 ! vacuolar lumen intersection_of: has_target_start_location GO:0005829 ! cytosol @@ -193747,7 +193747,7 @@ namespace: biological_process def: "The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate." [GOC:mah] synonym: "ferulate metabolism" EXACT [] intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:29749 ! ferulate +intersection_of: has_primary_input_or_output CHEBI:29749 ! trans-ferulate [Term] id: GO:0033495 @@ -193760,7 +193760,7 @@ synonym: "ferulate formation" EXACT [] synonym: "ferulate synthesis" EXACT [] xref: MetaCyc:PWY-5168 {source="skos:broadMatch"} intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:29749 ! ferulate +intersection_of: has_primary_output CHEBI:29749 ! trans-ferulate property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28388" xsd:anyURI [Term] @@ -204999,7 +204999,7 @@ def: "The process in which an amino acid is transported from one side of the vac comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "vacuolar amino acid membrane transport" EXACT [] intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion intersection_of: results_in_transport_across GO:0005774 ! vacuolar membrane [Term] @@ -205018,7 +205018,7 @@ name: neutral amino acid transmembrane export from vacuole namespace: biological_process def: "The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane." [GOC:mah] intersection_of: GO:0015804 ! neutral amino acid transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion intersection_of: has_target_end_location GO:0005829 ! cytosol intersection_of: has_target_start_location GO:0005775 ! vacuolar lumen intersection_of: results_in_transport_across GO:0016020 ! membrane @@ -205029,7 +205029,7 @@ name: basic amino acid transmembrane import into vacuole namespace: biological_process def: "The directed movement of basic amino acids into the vacuole across the vacuolar membrane." [GOC:mah] intersection_of: GO:0015802 ! basic amino acid transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion intersection_of: has_target_end_location GO:0005775 ! vacuolar lumen intersection_of: has_target_start_location GO:0005829 ! cytosol intersection_of: results_in_transport_across GO:0016020 ! membrane @@ -205040,7 +205040,7 @@ name: neutral amino acid transmembrane import into vacuole namespace: biological_process def: "The directed movement of neutral amino acids into the vacuole across the vacuolar membrane." [GOC:mah] intersection_of: GO:0015804 ! neutral amino acid transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion intersection_of: has_target_end_location GO:0005775 ! vacuolar lumen intersection_of: has_target_start_location GO:0005829 ! cytosol intersection_of: results_in_transport_across GO:0016020 ! membrane @@ -233207,7 +233207,7 @@ def: "Binding to interleukin-16." [GOC:jl] synonym: "IL-16 binding" EXACT [] is_a: GO:0019955 ! cytokine binding intersection_of: GO:0005488 ! binding -intersection_of: has_primary_input PR:000001374 ! interleukin-16 +intersection_of: has_primary_input PR:000001374 ! pro-interleukin-16 [Term] id: GO:0042012 @@ -233218,7 +233218,7 @@ synonym: "IL-16 receptor activity" EXACT [GOC:mah] synonym: "IL-16R" EXACT [] is_a: GO:0004896 ! cytokine receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_primary_input PR:000001374 ! interleukin-16 +intersection_of: has_primary_input PR:000001374 ! pro-interleukin-16 relationship: has_part GO:0042011 ! interleukin-16 binding [Term] @@ -235257,7 +235257,7 @@ synonym: "cellular modified amino acid catabolism" EXACT [GOC:mah] synonym: "cellular modified amino acid degradation" EXACT [GOC:mah] synonym: "modified amino acid catabolism" EXACT [GOC:mah] intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_input CHEBI:83821 ! amino-acid derivative property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] @@ -236923,7 +236923,7 @@ synonym: "cellular modified amino acid biosynthesis" EXACT [GOC:mah] synonym: "cellular modified amino acid formation" EXACT [GOC:mah] synonym: "cellular modified amino acid synthesis" EXACT [GOC:mah] intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_output CHEBI:83821 ! amino-acid derivative property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28908" xsd:anyURI [Term] @@ -243719,7 +243719,7 @@ namespace: biological_process def: "The directed movement of amino acids into a cell or organelle." [GOC:jl] synonym: "amino acid uptake" EXACT [] is_a: GO:0006810 ! transport -relationship: has_primary_input CHEBI:35238 ! amino acid zwitterion +relationship: has_primary_input CHEBI:35238 ! amino-acid zwitterion [Term] id: GO:0043093 @@ -244791,7 +244791,7 @@ def: "Any process that results in a change in state or activity of a cell or an synonym: "response to amino acid stimulus" EXACT [GOC:dos] is_a: GO:0001101 ! response to acid chemical intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion [Term] id: GO:0043201 @@ -330477,7 +330477,7 @@ synonym: "amino acid neurotransmitter recycling" BROAD [] synonym: "amino acid uptake during transmission of nerve impulse" RELATED [GOC:dph, GOC:tb] is_a: GO:0001504 ! neurotransmitter uptake intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion intersection_of: has_primary_input GOCHE:25512 ! substance with neurotransmitter role intersection_of: has_target_end_location GO:0099523 ! presynaptic cytosol intersection_of: has_target_start_location GO:0005576 ! extracellular region @@ -353879,7 +353879,7 @@ def: "The process in which a relatively unspecialized cell acquires specialized is_a: GO:0060487 ! lung epithelial cell differentiation is_a: GO:0061101 ! neuroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:1000223 ! lung neuroendocrine cell +intersection_of: results_in_acquisition_of_features_of CL:1000223 ! pulmonary neuroendocrine cell created_by: dph creation_date: 2010-04-27T03:28:46Z @@ -354311,7 +354311,7 @@ namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells." [GOC:cilia, GOC:dph, GOC:krc] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:1000271 ! lung ciliated cell +intersection_of: results_in_acquisition_of_features_of CL:1000271 ! lung multiciliated epithelial cell created_by: dph creation_date: 2010-05-25T09:31:14Z @@ -379384,7 +379384,7 @@ namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:mah] synonym: "cellular response to amino acid" EXACT [GOC:mah] intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion created_by: mah creation_date: 2009-12-03T02:08:11Z @@ -392189,7 +392189,7 @@ def: "The directed movement of modified amino acids into, out of or within a cel subset: gocheck_do_not_annotate synonym: "amino acid derivative transport" EXACT [] intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_input CHEBI:83821 ! amino-acid derivative created_by: mah creation_date: 2010-11-04T12:18:23Z @@ -392244,7 +392244,7 @@ def: "Binding to a modified amino acid." [GOC:mah] synonym: "amino acid derivative binding" EXACT [] is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding -intersection_of: has_primary_input CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_input CHEBI:83821 ! amino-acid derivative created_by: mah creation_date: 2010-11-04T05:45:32Z @@ -392329,7 +392329,7 @@ def: "Enables the transfer of modified amino acids from one side of a membrane t synonym: "amino acid derivative transmembrane transporter activity" EXACT [] synonym: "modified amino acid transporter activity" BROAD [GOC:mah] intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:83821 ! amino acid derivative +intersection_of: has_primary_input CHEBI:83821 ! amino-acid derivative relationship: part_of GO:0072337 ! modified amino acid transport created_by: mah creation_date: 2010-11-11T11:50:31Z @@ -401066,7 +401066,7 @@ def: "A homeostatic process involved in the maintenance of a steady state level synonym: "amino acid homeostasis" BROAD [] synonym: "cellular amino acid homeostasis" EXACT [] intersection_of: GO:0055082 ! intracellular chemical homeostasis -intersection_of: regulates_levels_of CHEBI:35238 ! amino acid zwitterion +intersection_of: regulates_levels_of CHEBI:35238 ! amino-acid zwitterion created_by: dhl creation_date: 2010-01-27T04:47:27Z @@ -403461,7 +403461,7 @@ synonym: "amino acid transmembrane import" BROAD [] synonym: "L-amino acid import" BROAD [] synonym: "L-amino acid uptake" NARROW [] intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion intersection_of: has_target_end_location GO:0005829 ! cytosol intersection_of: has_target_start_location GO:0005576 ! extracellular region intersection_of: results_in_transport_across GO:0005886 ! plasma membrane @@ -458046,7 +458046,7 @@ namespace: molecular_function def: "Binding to and responding, e.g. by conformational change, to changes in the cellular level of an amino acid." [GOC:pg] synonym: "amino acid sensing activity" EXACT [] intersection_of: GO:0140299 ! molecular sensor activity -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23126" xsd:anyURI created_by: pg creation_date: 2022-04-01T08:44:02Z @@ -458888,7 +458888,7 @@ namespace: molecular_function def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + monoatomic cation(in) = solute(in) + monoatomic cation(out). Monoatomic cations include H+, Mg2+, Ca2+, etc." [GOC:curators] intersection_of: GO:0015297 ! antiporter activity intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation -intersection_of: has_primary_input CHEBI:35238 ! amino acid zwitterion +intersection_of: has_primary_input CHEBI:35238 ! amino-acid zwitterion property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI created_by: pg creation_date: 2022-05-30T13:15:04Z @@ -464865,7 +464865,7 @@ namespace: cellular_component def: "A dense cluster of elongated, thick microvilli on the apical surface of tuft cells in epithelial tissues, such as the intestine and respiratory tract. The apical tuft extends further into the lumen than typical microvilli, featuring larger, more compact projections with unique actin cores that penetrate deep into the cytoplasm, often reaching the perinuclear region. This distinctive structure, rich in microfilaments and microtubules, supports the chemosensory functions of the cell." [PMID:15817800, PMID:35237268] is_a: GO:0098862 ! cluster of actin-based cell projections relationship: has_part GO:0005902 ! microvillus -relationship: part_of CL:0002204 +relationship: part_of CL:0002204 ! brush cell created_by: ce creation_date: 2024-11-14T11:13:07Z @@ -467384,6 +467384,7 @@ namespace: cellular_component def: "A protein complex containing Integrator and protein phosphatase 2A core enzyme (PP2A-AC) that stably associates with the C-terminus of RNA polymerase II and ptomotes premature RNA polymerase II transcription termination." [PMID:33243860, PMID:38570683] synonym: "integrator-PP2A complex" EXACT [] is_a: GO:0140513 ! nuclear protein-containing complex +relationship: has_part GO:0032039 ! integrator complex property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29515" xsd:anyURI created_by: rynl creation_date: 2025-01-07T21:54:49Z @@ -488314,7 +488315,7 @@ synonym: "ferulate breakdown" EXACT [GOC:TermGenie] synonym: "ferulate catabolism" EXACT [GOC:TermGenie] synonym: "ferulate degradation" EXACT [GOC:TermGenie] intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:29749 ! ferulate +intersection_of: has_primary_input CHEBI:29749 ! trans-ferulate created_by: tt creation_date: 2012-06-29T08:06:37Z @@ -497207,7 +497208,7 @@ namespace: biological_process def: "The chemical reactions and pathways involving an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid metabolism" EXACT [GOC:TermGenie] intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:78608 ! alpha-amino acid zwitterion +intersection_of: has_primary_input_or_output CHEBI:78608 ! alpha-amino-acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:50Z @@ -497220,7 +497221,7 @@ synonym: "alpha-amino acid breakdown" EXACT [GOC:TermGenie] synonym: "alpha-amino acid catabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid degradation" EXACT [GOC:TermGenie] intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:78608 ! alpha-amino acid zwitterion +intersection_of: has_primary_input CHEBI:78608 ! alpha-amino-acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:54Z @@ -497234,7 +497235,7 @@ synonym: "alpha-amino acid biosynthesis" EXACT [GOC:TermGenie] synonym: "alpha-amino acid formation" EXACT [GOC:TermGenie] synonym: "alpha-amino acid synthesis" EXACT [GOC:TermGenie] intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:78608 ! alpha-amino acid zwitterion +intersection_of: has_primary_output CHEBI:78608 ! alpha-amino-acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:58Z @@ -524712,7 +524713,7 @@ namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell." [GO_REF:0000086, GOC:sp, GOC:TermGenie, PMID:22231168, PMID:24934224] synonym: "multiciliate cell differentiation" BROAD [] intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:0005012 ! multi-ciliated epithelial cell +intersection_of: results_in_acquisition_of_features_of CL:0005012 ! multiciliated epithelial cell created_by: tb creation_date: 2014-08-05T19:21:21Z @@ -532575,7 +532576,7 @@ namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland." [GO_REF:0000086, GOC:TermGenie, PMID:17018284, PMID:18334552, PMID:19944183] synonym: "sebocyte differentiation" EXACT [CL:0002140] intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:0002140 ! acinar cell of sebaceous gland +intersection_of: results_in_acquisition_of_features_of CL:0002140 ! skin sebocyte created_by: cls creation_date: 2014-11-30T11:51:57Z @@ -582029,7 +582030,7 @@ def: "The multiplication or reproduction of sebocytes by cell division, resultin synonym: "sebocyte proliferation" RELATED [GOC:dph] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation -intersection_of: acts_on_population_of CL:0000317 ! sebum secreting cell +intersection_of: acts_on_population_of CL:0000317 ! sebocyte created_by: hjd creation_date: 2015-02-23T19:43:49Z