diff --git a/cmake/python-install.cmake.in b/cmake/python-install.cmake.in
index 95d6bd1dd2d..c4c5171cb02 100644
--- a/cmake/python-install.cmake.in
+++ b/cmake/python-install.cmake.in
@@ -2,9 +2,9 @@ if(DEFINED ENV{DESTDIR})
   # If DESTDIR is not absolute path, make it relative to @PROJECT_BINARY_DIR@
   # like any install() command.
   if(IS_ABSOLUTE $ENV{DESTDIR})
-    set(ROOT "--root=$ENV{DESTDIR}")
+    set(ROOT "--root='$ENV{DESTDIR}'")
   else()
-    set(ROOT "--root=@PROJECT_BINARY_DIR@/$ENV{DESTDIR}")
+    set(ROOT "--root='@PROJECT_BINARY_DIR@/$ENV{DESTDIR}'")
   endif()
 else()
   set(ROOT "")
@@ -13,7 +13,7 @@ endif()
 # Check if we have system Python on Debian/Ubuntu, if so tell setuptools
 # to use the deb layout (dist-packages instead of site-packages).
 execute_process(
-  COMMAND @Python3_EXECUTABLE@ -c "import sys; sys.stdout.write(sys.path[-1])"
+  COMMAND "@Python3_EXECUTABLE@" -c "import sys; sys.stdout.write(sys.path[-1])"
   OUTPUT_VARIABLE Python_STDLIB_DIR
 )
 if(Python_STDLIB_DIR MATCHES ".*/dist-packages$")
@@ -24,8 +24,8 @@ endif()
 
 execute_process(
   WORKING_DIRECTORY @PROJECT_BINARY_DIR@/python
-  COMMAND @Python3_EXECUTABLE@ setup.py install
+  COMMAND "@Python3_EXECUTABLE@" setup.py install
     ${ROOT}
-    --prefix=@CMAKE_INSTALL_PREFIX@
+    --prefix="@CMAKE_INSTALL_PREFIX@"
     ${SETUPTOOLS_INSTALL_LAYOUT}
 )