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Releases: icbi-lab/meRanTK

meRanTK_v1.3.0

15 Jun 10:46
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Version 1.3.0

  • meRanCall:
    Implemented a C-cutoff filter. Removes reads from poor conversion
    in the sense that if a read has more than C_cutoff Cs it will
    not be considered in m5C calling.
    Implement signal to noise ratio filter. Only consider sites
    that have a SNR higher than signalToNoise
    Implement a minimum C filter. Only consider sites that hav a
    minimum of minC Cs.

    Implemented gene level CR. meRanCall can now calculate the CR for
    each individual gene from a provided GTF file. This CR is than
    used in the statistical tests for the candidate sites in a
    corresponding gene.

    Implemented conflict solving for overlapping mates of a read pair.
    Only one base call, namely the one of the mate with the better
    quality score, is considered.

  • updated third party programs: STAR, HiSat2, bowtie2

  • provide a conda env YML file for meRanTK

  • added support for the current RefSeq mRNA fasta files from NCBI
    in the mkRefSeq2GeneMap.pl utility.

  • minor fixes