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Single cell data and spatial data matching requirement #44

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Chrisdoan9 opened this issue Dec 3, 2024 · 0 comments
Open

Single cell data and spatial data matching requirement #44

Chrisdoan9 opened this issue Dec 3, 2024 · 0 comments

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@Chrisdoan9
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Chrisdoan9 commented Dec 3, 2024

Hi CellTrek devs,

This tool is interesting so I would like to try. If I want to map a single cell dataset from a tissue of disease sample, the spatial data has to come from the same tissue and in the same disease condition. Maybe two dataset should come from the same individual. Is that correct? Could I use snRNA-seq from dorsolateral prefrontal cortex with spatial transcriptomics from prefrontal cortex? Beside snRNA-seq from dorsolateral prefrontal cortex, I also have snRNA-seq from anterior caudate and posterior cingulate cortex. May question is similar to the previous open issue. Thank you so much!

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