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<!DOCTYPE html>
<html>
<head>
<title>Nicolas Rosewick</title>
<meta charset="utf-8" />
<meta name="viewport" content="width=device-width, initial-scale=1">
<meta name="description" content="Nicolas Rosewick - bioinformatician">
<meta name="author" content="Nicolas Rosewick">
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<style>
.intro h1:before {
/* Edit this with your name or anything else */
content: 'ATGC';
}
</style>
</head>
<body>
<!-- Navigation -->
<div class="main-nav">
<div class="container">
<header class="group top-nav">
<div class="navigation-toggle" data-tools="navigation-toggle" data-target="#navbar-1">
<span class="logo">Nicolas Rosewick</span>
</div>
<nav id="navbar-1" class="navbar item-nav">
<ul>
<li class="active"><a href="#about">About</a></li>
<li><a href="#experiences">Experiences</a></li>
<li><a href="#skills">Skills</a></li>
<li><a href="#teaching">Teaching</a></li>
<li><a href="#publication">Publications</a></li>
<li><a href="#contact">Contact</a></li>
</ul>
</nav>
</header>
</div>
</div>
<!-- Introduction -->
<div class="intro section" id="about">
<div class="container">
<div class="units-row units-split wrap">
<div class="unit-20">
<img src="img/nico2.jpg" alt="Avatar">
</div>
<div class="unit-80">
<h1>Hi, I'm Nicolas Rosewick</h1>
I'm a belgian bioinformatician passionate about biological data analysis, 'omics and other cool stuffs.
</div>
<p>
</p>
</div>
</div>
</div>
<!-- Work Experience -->
<div class="work section second" id="experiences">
<div class="container">
<h1>Experiences</h1>
<ul class="work-list">
<li>08/2019-current</li>
<li><a href="#">Senior Bioinformatician</a></li>
<li>Erasme Hospital - Cliniques Universitaires de Bruxelles</li>
<li>Université Libre de Bruxelles </li>
<li><ul>
<li>- In charge of bioinformatics analysis in the Laboratory of Experimental Gastroenterology</li>
<li> - Focus on Next-Generation sequencing analysis (Whole Genome sequencing, RNA-Seq, single-cell sequencing, ...) in the context of Gastrointestinal diseases (HCC, IBD, NASH, ...) </li>
</ul>
<li>
</ul>
<ul class="work-list">
<li>04/2018-08/2019</li>
<li><a href="#">Project Leader Bioinformatics - Genomics</a></li>
<li>Sciensano - National Public Health Institute of Belgium</li>
<li><ul>
<li>- In charge of Next Generation Sequencing and genomics projects within Sciensano and Healthdata.be </li>
<li>- Developement and management of infrastructure for genomics data storage and bioinformatics data analysis. </li>
<li>- Management of Belgium-wide projects focused on NGS and genomics in the context of public health</li>
</ul>
<li>
</ul>
<ul class="work-list">
<li>01/2018-04/2018</li>
<li><a href="#">Bioinformatican in Translational Research </a></li>
<li>European Organisation for Research and Treatment of Cancer (EORTC)</li>
<li><ul>
<li>- Head of Bioinformatics data analysis within EORTC Translational Research Unit.</li>
<li>- Development of genomic and transcriptomic pipelines for multiple European clinical studies related to cancer.</li>
<li>- Creation and management of a clinical and genomic database centralizing data for European clinical studies.</li>
</ul>
<li>
</ul>
<ul class="work-list">
<li>2015-01/2018</li>
<li><a href="#">Bioinformatican - PostDoctoral Researcher - F.R.S.-FNRS Télévie </a></li>
<li>Laboratory of experimental hematology, Jules Bordet Institute, ULB, Belgium </li>
<li>Unit of Animal Genomics (Prof. M. Georges), GIGA, University of Liège</li>
<li><ul>
<li>- Genomic (DNA-Seq) and transcriptomic (RNA-Seq) approaches to study tumor evolution and intra-tumor heterogeneity in virus-induced leukemias (HTLV-1)</li>
<li>- Design of multiple analysis workflows (R, perl, bash,...) regarding ‘omics data.</li>
</ul>
<li>
</ul>
<ul class="work-list">
<li>2010-2015</li>
<li><a href="#">Ph.D. in Biomedial Sciences – Bioinformatics</a></li>
<li>Laboratory of experimental hematology, Jules Bordet Institute, ULB, Belgium </li>
<li>Unit of Animal Genomics (Prof. M. Georges), GIGA, University of Liège</li>
<li>
<ul>
<li>- Transcriptomic landscape of a virus induced leukemia (HTLV-1).
Bioinformatic analysis of DNA-Seq, RNA-Seq, smallRNA-Seq, ChiP-Seq, ...</li>
<li>- Bioinformatic workflow to identify virus-host chimeric transcripts</li>
</ul>
</li>
</ul>
<ul class="work-list">
<li>2007-2010</li>
<li><a href="#">Master in Bioinformatics and Modelling - Genomics, Proteomics and Evolution </a></li>
<li>Faculty of Sciences, Université Libre de Bruxelles (ULB), Belgium </li>
</div>
</div>
<!-- Technical Skills -->
<div class="skills section second" id="skills">
<div class="container">
<h1>Technical<br>Skills</h1>
<ul class="skill-list list-flat">
<li>#Bioinformatics</li>
<li><ul><li>High-Throughput sequencing ('Omics) data analysis</li>
<li>RNA-Seq : gene expression, fusion gene, alternative splicing, ...</li>
<li>DNA-Seq : Structural variant and SNP calling, ...</li>
<li>smallRNA-Seq, ChIP-Seq, ...</li>
<li>Various sequencing plateforms : Illumina, PacBio, Oxford Nanopore</li>
<li>Single-cell genomics </li>
<li>Epigenomics : Illumina 450K Infinium Methylation BeadChip array </li>
<li>microArray data analysis (limma,…) and qRT-PCR (Taqman LDA)</li>
<li>Various sequence alignment tools (bwa, bowtie, STAR, Blast, Blat, Clustal, GMAP,...) </li>
<li>Biological databases: ENSEMBL, UCSC, GDC-TCGA, COSMIC, Kegg, ... </li>
</ul>
</li>
</ul>
<ul class="skill-list list-flat">
<li>#Statistics</li>
<li><ul><li>Machine learning applied to high-dimensional/large-scale biological data</li>
<li>Supervised and unsupervised clustering and classification</li>
<li>Regression analysis : linear regression, GLM, cross-validation</li>
<li>Uni- and multi-variate analysis</li>
<li>Very good proficiency in R (Tidyverse, Bioconductor)</li>
</ul>
</li>
</ul>
</div>
</div>
<div class="award section second" id="teaching">
<div class="container">
<h1>Teaching</h1>
<ul class="award-list list-flat">
<li>2016 and 2017 workshop organizer/lecturer:
– Introduction to High-Throughput Sequencing (RNA-Seq),
part of the Belgian Doctoral School in Cancerology</li>
</ul>
</div>
</div>
<!-- Award & Achievements -->
<div class="award section second" id="publication">
<div class="container">
<h1>Publications</h1>
<ul class="award-list list-flat">
<li><a target="_blank" href="https://www.nature.com/leu/journal/vaop/naam/abs/leu2017260a.html"><b>Monitoring molecular response in adult t-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality</b>, M. Artesi*, A. Marcais*, K. Durkin, <u>N. Rosewick</u>, V. Hahaut, F. Suarez, A. Trinquand, L. Lhermitte, V. Asnafi, A V. Fenoel, A. Burny, M. Georges, O. Hermine, A. Van den Broeke , Leukemia, doi: 10.1038/leu.2017.260, August 2017.</a></li>
</ul>
<ul class="award-list list-flat">
<li><a target="_blank" href="https://www.nature.com/articles/ncomms15890"><b>HTLV-1-Induced Leukotriene B4 Secretion by T Cells Promotes T Cell Recruitment and Virus Propagation</b>, F. Percher*, C. Curis*, E. Pérès*, M. Artesi, <u>N. Rosewick</u>, P. Jeannin, A. Gessain, O. Gout, R. Mahieux, P-E. Ceccaldi,A. Van den Broeke, M. Duc Dodon, P V. Afonso, Nature Communications, doi:10.1038/ncomms15890, June 2017.</a></li>
</ul>
<ul class="award-list list-flat">
<li><a target="_blank" href="https://www.nature.com/articles/ncomms15264"><b>Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is a major early determinant of leukemogenesis</b>, <u>N. Rosewick</u>*, K. Durkin*, M. Artesi*, A. Marçais, V. Hahaut, P. Griebel, N. Arsic, V. Avettand-Fenoel, A. Burny, C. Charlier, O. Hermine, M. Georges, A. Van den Broeke,. Nature Communications, 8, 15264 doi : 10,1038/ncomms15264, May 2017. </a></li>
</ul>
<ul class="award-list list-flat">
<li><a target="_blank" href="https://retrovirology.biomedcentral.com/articles/10.1186/s12977-016-0267-8"><b>Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts by deep sequencing reveals constitutive expression in tumors and transcriptional interaction with viral microRNAs</b>,K. Durkin, <u>N. Rosewick</u>,M. Artesi, V. Hahaut, P. Griebel, N. Arsic, A. Burny, M. Georges, A. Van den Broeke, Retrovirology, vol. 13, no 1, p. 1. doi:10.1186/s12977-016-0267-8, May 2016</a></li>
</ul>
<ul class="award-list list-flat">
<li><a target="_blank" href="http://www.pnas.org/content/110/6/2306.long"><b>Deep sequencing reveals abundant noncanonical retroviral microRNAs in B-cell leukemia/lymphoma</b>, <u>N. Rosewick</u>, M. Momont, K. Durkin, H. Takeda, F. Caiment, Y. Cleuter, C. Vernin, F. Mortreux, E Wattel, A. Burny, M. Georges, A. Van den Broeke , PNAS (Proc. Natl. Acad. Sci. U.S.A.), vol.110, no. 6, pp. 2306-2311, doi: 10.1073/pnas.1213842110, Feb 2013.</a></li>
</ul>
</div>
</div>
<div class="award section second" id="contact">
<div class="container">
<h1>Contact</h1>
<ul class="award-list list-flat">
<li>[email protected]</li>
<li>+32 (0) 494 82 97 71</li>
<li><a target="_blank" href="https://www.linkedin.com/in/nrosewick">linkedin.com/in/nrosewick</a></li>
<li><a target="_blank" href="https://www.twitter.com/nrosewick">@nrosewick</a></li>
</ul>
</div>
</div>
<!-- Quote -->
<div class="quote">
<div class="container text-centered">
<h1>Nicolas Rosewick</h1>
</div>
</div>
<footer>
<div class="container">
<div class="units-row">
<div class="unit-50">
<p>Nicolas Rosewick</p>
</div>
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<li><a href="mailto:[email protected]"><i class="fa fa-send"></i></a></li>
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