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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="utf-8" />
<meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no" />
<meta name="description" content="" />
<meta name="author" content="" />
<title>Ahsan Polash | Resume</title>
<link rel="icon" type="image/x-icon" href="assets/img/favicon.ico" />
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<script src="https://use.fontawesome.com/releases/v5.13.0/js/all.js" crossorigin="anonymous"></script>
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<!-- Core theme CSS (includes Bootstrap)-->
<link href="dist/css/styles.css" rel="stylesheet" />
<!-- Academicon ADDED BY AHSAN-->
<link rel="stylesheet" href="academicon/css/academicons.min.css"/>
</head>
<body id="page-top">
<!-- Navigation-->
<nav class="navbar navbar-expand-lg navbar-dark bg-primary fixed-top" id="sideNav">
<a class="navbar-brand js-scroll-trigger" href="#page-top"
><span class="d-block d-lg-none">Polash Ahsan Habib</span><span class="d-none d-lg-block"><img class="img-fluid img-profile rounded-circle mx-auto mb-2" src="dist/assets/img/profile_ahsan.jpg" alt="" /></span></a
><button class="navbar-toggler" type="button" data-toggle="collapse" data-target="#navbarSupportedContent" aria-controls="navbarSupportedContent" aria-expanded="false" aria-label="Toggle navigation"><span class="navbar-toggler-icon"></span></button>
<div class="collapse navbar-collapse" id="navbarSupportedContent">
<ul class="navbar-nav">
<li class="nav-item"><a class="nav-link js-scroll-trigger" href="#about">About</a></li>
<li class="nav-item"><a class="nav-link js-scroll-trigger" href="#experience">Experience</a></li>
<li class="nav-item"><a class="nav-link js-scroll-trigger" href="#education">Education</a></li>
<li class="nav-item"><a class="nav-link js-scroll-trigger" href="#skills">Skills</a></li>
<li class="nav-item"><a class="nav-link js-scroll-trigger" href="#publications">Publications</a></li>
<li class="nav-item"><a class="nav-link js-scroll-trigger" href="#interests">Interests</a></li>
<!--li class="nav-item"><a class="nav-link js-scroll-trigger" href="#publications">Publications</a></li-->
</ul>
</div>
</nav>
<!-- Page Content-->
<div class="container-fluid p-0">
<!-- About-->
<section class="resume-section" id="about">
<div class="resume-section-content">
<h1 class="mb-0">Polash <span class="text-primary">Ahsan Habib </span></h1>
<div class="subheading mb-5">Kyoto University, Graduate School of medicine · <a href="mailto:[email protected]">personal gmail</a> · <a href="mailto:[email protected]">institutional mail</a></div>
<!--p class="lead mb-5"-->
<p style="font-size:18px;">I am enrolled as a doctoral student at Radiation Genetics Lab of Graduate School of Medicine, Kyoto University.
<br/>Although my lab focuses on Genotoxicity and Carcinogenesis, my research focus is including, but not limited to, Cheminformatics/Chemoinformatics, Computational Biology, Medicinal Chemistry, Life Science Informatics and Immunoinformatics.<br/>
<br/>I have been studying application of Artificial Intelligence for drug discovery and chemical toxicity for my doctoral research.
<br/>I often employ computational resources to study kinase inhibitors and to predict toxicity of chemical compounds.
<br/>Very often Machine Learning (ML) algorithms are applied in my working strategies to elucidate the Structure Activity Relationship (SAR) of chemical compounds and I am eager to deconvolute the decision making processes by ML.<br/>
<br/>I am highly knowledgable about NGS data (ChIP-seq/RNA-seq/CAGE data) analysis.
<br/>I have analyzed transcriptomics data to evaluate the effect of small molecules to cell line models so that their role in DNA repair dynamics and carcinogenesis is understood. I am familiar with public databases like TCGA, ENCODE etc.<br/>
<br/>By training I am a molecular biologist. I have experiences with cell biology experiemnts, i.e clonogenic cell survival assays, DNA repair kinetics etc.<br/>
<br/>As a data vizualization enthuast I often discuss biological data handling and representation with my collleagues.</p><br/>
<div class="social-icons">
<a class="social-icon" href="https://www.linkedin.com/in/paulahsan/" target="_blank"><i class="fab fa-linkedin-in"></i></a>
<a class="social-icon" href="https://www.researchgate.net/profile/Ahsan_Polash" target="_blank"><i class="ai ai-researchgate fa-lg"></i></a>
<a class="social-icon" href="https://scholar.google.com/citations?hl=en&user=6uAR5RsAAAAJ&view_op=list_works&sortby=pubdate" target="_blank"><i class="ai ai-google-scholar fa-lg"></i>
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<a class="social-icon" href="dist/assets/pdfs/AhsanCV_website.pdf" target="_blank"><i class="ai ai-cv fa-lg"></i></a>
<!--i class="fab fa-google"></i-->
<!--a class="social-icon" href="#"><i class="fab fa-twitter"></i></a>a class="social-icon" href="#"><i class="fab fa-facebook-f"></i></a-->
</div>
</div>
</section>
<hr class="m-0" />
<!-- Experience-->
<section class="resume-section" id="experience">
<div class="resume-section-content">
<h2 class="mb-5">Experience</h2>
<div class="d-flex flex-column flex-md-row justify-content-between mb-5">
<div class="flex-grow-1">
<h3 class="mb-0">Doctoral Student</h3>
<!--RG Lab affil-->
<div class="subheading mb-3"> <a href="http://www.med.kyoto-u.ac.jp/en/organization-staff/research/doctoral_course/r-016/" target="_blank" > Radiation Genetics Lab </a></div>
<p>Joined this lab as a research assistant and later enrolled for doctoral study</p>
<p>Participated Projects:</p>
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Analyze transcriptomics data to evaluate the effect of androgen to cell line models so that their role in DNA repair dynamics and carcinogenesis is understood
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Determine genotoxicity of chemical compounds via clonogenic cell survival assay
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Measure DNA repair dynamic via Immunochemistry (Immunostaining for gH2AX foci and RAD51 foci) and Microscopy
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Preparation of modified DNA plasmid by editing vector DNA
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>General Molecular Biology Techniques (DNA extraction, PCR etc)
</li>
</ul>
</div>
<div class="flex-shrink-0"><span class="text-primary">July 2016 - Present (Currently enrolled as Doctoral student)</span></div>
</div>
<!--JB Lab affil-->
<div class="d-flex flex-column flex-md-row justify-content-between mb-5">
<div class="flex-grow-1">
<div class="subheading mb-3"> <a href="http://statlsi.med.kyoto-u.ac.jp/jbbrown/publications/#publications" target="_blank"> Life Science Informatics Research Unit </a></div>
<p>This is a lab under Department of Molecular Biosciences. Here I started working in the field of cheminformatics</p>
<p>Participated Projects:
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Implementation of Active Learning
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Employ Active Learning for matrix metalloproteinases (MMP) inhibitors
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Active Learning for acute oral toxicity prediction
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Modeling of CYP450 and Deorphanizing nuclear hormone receptor by Active Learning
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Visualisation of machine learning decision making process
</li>
</ul>
</p>
</div>
</div>
<div class="d-flex flex-column flex-md-row justify-content-between mb-5">
<div class="flex-grow-1">
<h3 class="mb-0">Lecturer</h3>
<div class="subheading mb-3"> <a href="http://sls.iub.edu.bd/faculty-2/" target="_blank"> Independent University Bangladesh </a></div>
<p>Acted as lecturer for the undergraduate students of Life Sciences.</p>
<p>Conducted Courses:
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Introductory Biology
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Physical Chemistry
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Biotechnology
</li>
<li>
<span class="fa-li"><i class="fas fa-hashtag"></i></span>Bioinformatics
</li>
</ul>
</p>
</div>
<div class="flex-shrink-0"><span class="text-primary">April 2013 - July 2016 (Currently on Study Leave)</span></div>
</div>
<!--HK Lab affil-->
<div class="d-flex flex-column flex-md-row justify-content-between mb-5">
<div class="flex-grow-1">
<h3 class="mb-0">Research Associate</h3>
<div class="subheading mb-3"> <a href="http://molbiolab.du.ac.bd/alumni.html" target="_blank"> Molecular Biology Lab</a></div>
<p>Immediately after finishing my MS, I joined the same lab where I did my MS thesis as research associate. I worked in a project to identify novel endophytes of Jute</p>
</div>
<div class="flex-shrink-0"><span class="text-primary">December 2011 - March 2013</span></div>
</div>
<div class="d-flex flex-column flex-md-row justify-content-between mb-5">
<div class="flex-grow-1">
<h3 class="mb-0">Elective Research Fellow</h3>
<div class="subheading mb-3"> <a href="http://molbiolab.du.ac.bd/alumni.html" target="_blank"> Molecular Biology Lab</a></div>
<p>In this lab I studied for my MS thesis<br/>
I studied salt stress responsive pathways of Jute and identified novel Jute miRNA related to salt stress response</p>
</div>
<div class="flex-shrink-0"><span class="text-primary">August 2010 - December 2011</span></div>
</div>
</div>
</section>
<hr class="m-0" />
<!-- Education-->
<section class="resume-section" id="education">
<div class="resume-section-content">
<h2 class="mb-5">Education</h2>
<!-- Doctoral-->
<div class="d-flex flex-column flex-md-row justify-content-between mb-5">
<div class="flex-grow-1">
<h3 class="mb-0">Doctoral Study</h3>
<div class="subheading mb-3">Kyoto University</div>
<div>Graduate School of Medicine<br>Deapartment of Radiation Genetics
<!--br><br>Laboratory of Molecular Biosciences<br>Life Science Informatics Research Unit-->
</div>
<!--p>GPA: 3.23</p-->
</div>
<div class="flex-shrink-0"><span class="text-primary">April 2017 - Present (Projected timeline March 2021)</span></div>
</div>
<!-- INTERNSHIP -->
<!--div class="d-flex flex-column flex-md-row justify-content-between mb-5">
<div class="flex-grow-1">
<h3 class="mb-0">University of Bonn</h3>
<div class="subheading mb-3">Internship</div>
<p>GPA: 3.56</p>
<p>Department of Biochemistry and Molecular Biology<br></p>
</div>
<div class="flex-shrink-0"><span class="text-primary">August 2010 - December 2011</span></div>
</div--!>
<!-- MS -->
<div class="d-flex flex-column flex-md-row justify-content-between mb-5">
<div class="flex-grow-1">
<h3 class="mb-0">Master of Science (MS)</h3>
<div class="subheading mb-3">University of Dhaka</div>
<!--p>GPA: 3.56</p-->
<p>Department of Biochemistry and Molecular Biology<br></p>
</div>
<div class="flex-shrink-0"><span class="text-primary">August 2010 - December 2011</span></div>
</div>
<!-- BS -->
<div class="d-flex flex-column flex-md-row justify-content-between">
<div class="flex-grow-1">
<h3 class="mb-0">Bachelor of Science, B.S. (Honours)</h3>
<div class="subheading mb-3">University of Dhaka</div>
<!--p>GPA: 3.56</p-->
<p>Department of Biochemistry and Molecular Biology<br></p>
</div>
<div class="flex-shrink-0"><span class="text-primary">April 2006 - August 2010</span></div>
</div>
</div>
</section>
<hr class="m-0" />
<!-- Skills-->
<section class="resume-section" id="skills">
<div class="resume-section-content">
<h2 class="mb-5">Skills</h2>
<div class="subheading mb-3"><i class="fas fa-desktop"></i> Cheminformatics skills</div>
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Chemogenomic data extraction (ChEMBL/PubChem)
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Cheminformatics tools (RDKit, OpenEye)
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>QSAR snalysis
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Machine Learning/Active Learning (RF, SVM, Scikit-learn)
</li>
</ul><br>
<div class="subheading mb-3"><i class="fas fa-dna"></i> Computational Biology Skill</div>
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Handling of NGS data (CAGE, ChIP-Seq, RNA-seq)
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Performing exploratory analysis of tracscriptome to understand gene regulation
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Data curartion and vizualization from public databases (TCGA, ENCODE, NCBI)
</li>
</ul><br>
<div class="subheading mb-3"><i class="fas fa-microscope"></i> Cell biology skill</div>
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Human cell line (TK-6 and MCF-7) maintainance
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Clonogenic cell survival assay
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Immunochemistry (Immunostaining for gH2AX foci and RAD51 foci) & Microscopy
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>General Molecular Biology Techniques (DNA extraction, PCR etc)
</li>
</ul><br>
<div class="subheading mb-3"><i class="fas fa-chart-bar"></i> Data analysis skill</div>
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Data processing (Pandas and Numpy)
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Data visualization (Matplotlib and Seaborn)
</li>
<!--li>
<span class="fa-li"><i class="fas fa-circle"></i></span>QSAR snalysis
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Machine Learning/Active Learning (RF, SVM, Scikit-learn)
</li-->
</ul><br>
<div class="subheading mb-3"><i class="fas fa-terminal"></i> Programming Languages & Tools</div>
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Capable of writing Reusable and maintainable Python code
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Bash and Zsh shell
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>R (Basic to Intermediate)
</li>
</ul><br>
<div class="subheading mb-3"><i class="fas fa-language"></i> Language Skill</div>
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Bangla: native speaker
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>English: Professional (IELTS:7/9, TOEIC: 940/950)
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>Japanes (Preliminary)
</li>
</ul><br>
</div>
</section>
<hr class="m-0" />
<!-- Publications-->
<section class="resume-section" id="publications">
<div class="resume-section-content">
<h2 class="mb-5">Publications</h2>
<ul class="fa-ul mb-0">
<li>
<span class="fa-li"><i class="ai ai-google-scholar ai-2x text-warning"></i></span>
<!--i class="fas fa-graduation-cap text-warning"></i--!></span--!>
<a href="https://scholar.google.com/citations?hl=en&user=6uAR5RsAAAAJ&view_op=list_works&sortby=pubdate"
target="_blank" >
My google scholar profile</a>
</li><br>
<!--Publication manually ADDED by Ahsan-->
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>
(2020) <b>AhsanHabib Polash</b>, TakumiNakano. Christin Rakers ShunichiTakeda, J.B.Brown<br/>
<a href="https://www.sciencedirect.com/science/article/abs/pii/S2468111320300396" target="_blank">
“Active learning efficiently converges on rational limits of toxicity prediction and
identifies patterns for molecule design”</a>
<br/>
<em>Computational Toxicology 2020, (15), 100129</em>
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>
(2019) <b>Ahsan Habib Polash</b>, Takumi Nakano, Shunichi Takeda, JB Brown <br />
<a href="https://www.mdpi.com/1420-3049/24/15/2716/pdf" target="_blank">
Applicability Domain of Active Learning in Chemical Probe Identification:
Convergence in Learning from Non-Specific Compounds and Decision Rule Clarification</a>
<br />
<em>Molecules 2019, 24(15), 2716</em>
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>
(2019) <b>Ahsan Habib Polash</b>, Takumi Nakano, Shunichi Takeda, JB Brown <br/>
<a href="https://www.jstage.jst.go.jp/article/cicsj/37/1/37_12/_pdf" target="_blank">
Systematic approaches to build predictive models for rat oral toxicity</a><br/>
<em>CICSJ Bulletin 2019, 37(1), 12</em>
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>
(2018) Christin Rakers, Rifat Ara Najnin, <b>Ahsan Habib Polash</b>, Shunichi Takeda, JB Brown<br>
<a href="https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201700677" target="_blank">
Chemogenomic Active Learning's Domain of Applicability on Small, Sparse qHTS Matrices:
A Study Using Cytochrome P450 and Nuclear Hormone Receptor Families</a>,<br>
<em>ChemMedChem 2018, 13, 511.<br>
*Designated Very Important Paper based on peer review reports.
</em>
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>
<b>Book chapter</b><br/>
(2018)Rasel Al Mahmud, Rifat Ara Najnin, <b>Ahsan Habib Polash</b>,<br>
<a href="https://link.springer.com/protocol/10.1007/978-1-4939-8639-2_1" target="_blank">
A Survey of Web-Based Chemogenomic Data Resources.
In: Brown J. (eds) Computational Chemogenomics</a><br>
<em>Methods in Molecular Biology, vol 1825. Humana Press, New York, NY<br>
*Equal contribution</em>
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>
(2015) Rifat Ara Najnin, Farhana Shafrin, <b>Ahsan Habib Polash</b>,
Aubhishek Zaman, Amzad Hossain, Taha Taha, Rajib Ahmed, Jannatul Ferdoush Tuli,
Rashu Barua, Abu Ashfaqur Sajib, Haseena Khan<br>
<a href="https://link.springer.com/article/10.1007/s13213-014-1001-1" target="_blank">
A diverse community of jute (<em>Corchorus spp.</em>)
endophytes reveals mutualistic host–microbe interactions</a><br>
<em>Annals of Microbiology 65: 1615</em>
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>
(2013) Chinmoy Saha,<b> Ahsan Habib Polash</b>, Md Tariqul Islam, Farhana Shafrin<br>
<a href="https://link.springer.com/article/10.1007/s12539-013-0178-5" target="_blank">
<em>In silico</em> prediction of structure and functions for some proteins of
male-specific region of the human Y chromosome</a>,<br>
<em>Interdisciplinary Sciences: Computational Life Sciences 5: 258</em>
</li>
<li>
<span class="fa-li"><i class="fas fa-circle"></i></span>
(2013) Md Rezaul Islam, <b>Ahsan Habib Polash</b>,
M Sadman Sakib, Chinmoy Saha, Atiqur Rahman<br>
<a href="https://wireilla.com/papers/ijbb/V3N2/3213ijbb05.pdf" target="_blank">
Computational identification of Brassica napus pollen specific
protein Bnm1 as an allergen</a><br>
<em>International Journal on Bioinformatics & Biosciences (IJBB) Vol.3, No.2</em>
</li>
<!--Publication manually ADDED by Ahsan ENDS-->
<!--li>
<span class="fa-li"><i class="fas fa-trophy text-warning"></i></span>Mobile Web Specialist - Google Certification
</li>
<li>
<span class="fa-li"><i class="fas fa-trophy text-warning"></i></span>1<sup>st </sup>Place - University of Colorado Boulder - Emerging Tech Competition 2009
</li>
<li>
<span class="fa-li"><i class="fas fa-trophy text-warning"></i></span>1<sup>st </sup>Place - University of Colorado Boulder - Adobe Creative Jam 2008 (UI Design Category)
</li>
<li>
<span class="fa-li"><i class="fas fa-trophy text-warning"></i></span>2<sup>nd </sup>Place - University of Colorado Boulder - Emerging Tech Competition 2008
</li>
<li>
<span class="fa-li"><i class="fas fa-trophy text-warning"></i></span>1<sup>st </sup>Place - James Buchanan High School - Hackathon 2006
</li>
<li>
<span class="fa-li"><i class="fas fa-trophy text-warning"></i></span>3<sup>rd </sup>Place - James Buchanan High School - Hackathon 2005
</li-->
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<!-- Interests-->
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<h2 class="mb-5">Interests</h2>
<p>Apart from being a computational chemist/biologist, I enjoy my time with reading blogs, watching movies<br/>
I am a coffeeholic, love to try different blends of coffee<br/><br/>
As an aspiring chef, I have interest for different cuisins around the world<br/><br/>
I enjoy hiking and cycling<br/>
While going out for sight seeing I do not forget to bring a camera</p>
<!--p class="mb-0">When forced indoors, I follow a number of sci-fi and fantasy genre movies and television shows, I am an aspiring chef, and I spend a large amount of my free time exploring the latest technology advancements in the front-end web development world.</p-->
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