From 4bc393a728b382ca9c499edfc992383b06221cea Mon Sep 17 00:00:00 2001 From: gurdeep330 <[gurdeep330@gmail.com]> Date: Thu, 27 Jan 2022 17:47:19 +0100 Subject: [PATCH] update README --- webApp/about.html | 8 +++----- 1 file changed, 3 insertions(+), 5 deletions(-) diff --git a/webApp/about.html b/webApp/about.html index 3effc8883..8a7132757 100644 --- a/webApp/about.html +++ b/webApp/about.html @@ -1,12 +1,10 @@ - @@ -22,7 +20,7 @@

Introduction

of disease-linked mutation.

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Commptational method

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Computational method

We used the command-line version of the SignalP4.1 program. The program takes a sequence (FASTA formatted) of 70 amino acids length as input and predicts the @@ -39,13 +37,13 @@

Commptational method

UniProt, COSMIC, and ClinVAR.

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Validation experiments

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Validation

Validation of the hits were then performed by ectopically expressing wt and mutant constructs in wt HEK293T cells or lacking the regulatory SPC subunit SPCS1 and cell lysates were then analysed via Western blot to detect possible SPCS1-dependent cleavage fragments (see methods for details).

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Contacts

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Contact

Gurdeep Singh: gurdeep.singh@bioquant.uni-heidelberg.de (Russell lab, Heidelberg)
Andrea Zanotti: a.zanotti@zmbh.uni-heidelberg.de (Lemberg lab, Heidelberg/Cologne)