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@@ -0,0 +1,15156 @@ +Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Consequence Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer t_ref_count t_alt_count n_ref_count n_alt_count HGVSc HGVSp HGVSp_Short Transcript_ID RefSeq Protein_position Codons Hotspot +ANK2 UCSF GRCh37 4 114257011 114257011 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 27 5 40 1 ENST00000357077.4:c.3389G>A p.Ser1130Asn p.S1130N ENST00000357077 NM_001148.4 1130 aGc/aAc 0 +ATRX UCSF GRCh37 X 76938230 76938231 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Pri Untested WXS Illumina HiSeq 45 0 ENST00000373344.5:c.2518dup p.Arg840LysfsTer9 p.R840Kfs*9 ENST00000373344 NM_000489.3 839 -/A 0 +BCLAF1 UCSF GRCh37 6 136599392 136599392 + synonymous_variant Silent SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 151 31 206 0 ENST00000531224.1:c.627C>T p.Ser209= p.S209= ENST00000531224 NM_001077441.1 209 tcC/tcT 0 +BDP1 UCSF GRCh37 5 70811923 70811923 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 32 13 45 0 ENST00000358731.4:c.4685A>G p.Lys1562Arg p.K1562R ENST00000358731 NM_018429.2 1562 aAg/aGg 0 +BRIX1 UCSF GRCh37 5 34925341 34925341 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Pri Untested WXS Illumina HiSeq 20 6 31 0 ENST00000336767.5:c.803T>C p.Val268Ala p.V268A ENST00000336767 NM_018321.3 268 gTc/gCc 0 +CDHR5 UCSF GRCh37 11 618860 618860 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.029 P01_Pri Untested WXS Illumina HiSeq 21 3 24 1 ENST00000358353.3:c.1699A>G p.Ser567Gly p.S567G ENST00000358353 567 Agt/Ggt 0 +CES1 UCSF GRCh37 16 55862883 55862883 + missense_variant,splice_region_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.320,snp132_rs34380375 P01_Pri Untested WXS Illumina HiSeq 14 6 25 1 ENST00000361503.4:c.53G>T p.Gly18Val p.G18V ENST00000361503 18 gGg/gTg 0 +CHRM2 UCSF GRCh37 7 136701008 136701008 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 41 5 64 0 ENST00000320658.5:c.1396A>G p.Arg466Gly p.R466G ENST00000320658 NM_001006632.1 466 Agg/Ggg 0 +CNOT4 UCSF GRCh37 7 135122975 135122975 + stop_gained Nonsense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 40 6 48 1 ENST00000315544.5:c.105C>A p.Tyr35Ter p.Y35* ENST00000315544 NM_001190848.1 35 taC/taA 0 +DDR1 UCSF GRCh37 6 30864491 30864491 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 31 24 25 0 ENST00000324771.8:c.1718A>G p.Asp573Gly p.D573G ENST00000324771 573 gAc/gGc 0 +DLC1 UCSF GRCh37 8 12950182 12950182 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 21 6 37 0 ENST00000276297.4:c.3679G>A p.Val1227Met p.V1227M ENST00000276297 NM_182643.2 1227 Gtg/Atg 0 +ERBB2IP UCSF GRCh37 5 65371004 65371004 + synonymous_variant Silent SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 54 21 89 0 ENST00000284037.5:c.3909A>G p.Pro1303= p.P1303= ENST00000284037 NM_001253697.1 1303 ccA/ccG 0 +FBXO18 UCSF GRCh37 10 5965617 5965617 + missense_variant Missense_Mutation SNP G G C NOVEL P01_Pri Untested WXS Illumina HiSeq 37 19 61 0 ENST00000362091.4:c.2356G>C p.Asp786His p.D786H ENST00000362091 NM_001258453.1 786 Gat/Cat 0 +FYB UCSF GRCh37 5 39122471 39122471 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 31 5 52 1 ENST00000351578.6:c.1967C>A p.Thr656Asn p.T656N ENST00000351578 NM_199335.3 656 aCc/aAc 0 +HGSNAT UCSF GRCh37 8 43046714 43046714 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Pri Untested WXS Illumina HiSeq 33 12 56 0 ENST00000379644.4:c.1226T>C p.Leu409Pro p.L409P ENST00000379644 NM_152419.2 409 cTc/cCc 0 +HLA-C UCSF GRCh37 6 31238897 31238897 + missense_variant Missense_Mutation SNP C C G NOVEL P01_Pri Untested WXS Illumina HiSeq 39 6 25 1 ENST00000376228.5:c.572G>C p.Trp191Ser p.W191S ENST00000376228 NM_002117.5 191 tGg/tCg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 40 21 74 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIF3C UCSF GRCh37 2 26204031 26204031 + synonymous_variant Silent SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 12 3 15 0 ENST00000264712.3:c.756G>A p.Arg252= p.R252= ENST00000264712 NM_002254.6 252 agG/agA 0 +KIR2DS4 UCSF GRCh37 19 55350964 55350965 + stop_gained,frameshift_variant Nonsense_Mutation INS - - CCCGGAGCTCCTATGACATGTA snp132_rs35757649 P01_Pri Untested WXS Illumina HiSeq 6 0 ENST00000339924.8:c.453_454insCCGGAGCTCCTATGACATGTAC p.Ile152ProfsTer5 p.I152Pfs*5 ENST00000339924 NM_001281971.1 151 tcc/tcCCCGGAGCTCCTATGACATGTAc 0 +LOXL4 UCSF GRCh37 10 100013411 100013411 + stop_gained Nonsense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 13 7 28 1 ENST00000260702.3:c.1734C>A p.Tyr578Ter p.Y578* ENST00000260702 NM_032211.6 578 taC/taA 0 +LTK UCSF GRCh37 15 41796420 41796420 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 12 4 22 0 ENST00000263800.6:c.2369T>C p.Leu790Pro p.L790P ENST00000263800 NM_002344.5 790 cTc/cCc 0 +MGAT4A UCSF GRCh37 2 99342774 99342774 + missense_variant Missense_Mutation SNP C C A snp132_rs79141144 P01_Pri Untested WXS Illumina HiSeq 28 4 35 1 ENST00000264968.3:c.22G>T p.Val8Leu p.V8L ENST00000264968 8 Gta/Tta 0 +MYH9 UCSF GRCh37 22 36717828 36717828 + stop_gained Nonsense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 29 5 36 0 ENST00000216181.5:c.744C>A p.Tyr248Ter p.Y248* ENST00000216181 NM_002473.4 248 taC/taA 0 +MYOCD UCSF GRCh37 17 12666467 12666467 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 45 23 77 0 ENST00000343344.4:c.2323A>G p.Thr775Ala p.T775A ENST00000343344 775 Act/Gct 0 +MYOCD UCSF GRCh37 17 12620673 12620673 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 17 4 58 0 ENST00000343344.4:c.188C>T p.Ser63Phe p.S63F ENST00000343344 63 tCc/tTc 0 +NUDT10 UCSF GRCh37 X 51076024 51076024 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.00397,1000g2011may_all_0.0126,snp132_rs2801626 P01_Pri Untested WXS Illumina HiSeq 13 3 10 0 ENST00000356450.2:c.207G>A p.Glu69= p.E69= ENST00000356450 69 gaG/gaA 0 +OR7C2 UCSF GRCh37 19 15052698 15052698 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 70 38 127 0 ENST00000248072.3:c.398C>T p.Thr133Met p.T133M ENST00000248072 NM_012377.1 133 aCg/aTg 0 +OVOL2 UCSF GRCh37 20 18005411 18005411 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 23 7 38 0 ENST00000278780.6:c.697G>A p.Val233Met p.V233M ENST00000278780 NM_021220.2 233 Gtg/Atg 0 +PRB1 UCSF GRCh37 12 11506582 11506582 + intron_variant Intron SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 41 6 35 1 ENST00000500254.2:c.313+142G>A *105* ENST00000500254 NM_199353.2 0 +PRKAB1 UCSF GRCh37 12 120114413 120114413 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 31 17 51 0 ENST00000229328.5:c.604G>A p.Ala202Thr p.A202T ENST00000229328 NM_006253.4 202 Gca/Aca 0 +PSG7 UCSF GRCh37 19 43430146 43430146 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 113 14 150 0 ENST00000406070.2:c.1022T>C p.Phe341Ser p.F341S ENST00000406070 NM_002783.2 341 tTc/tCc 0 +PSMD13 UCSF GRCh37 11 248855 248855 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 24 12 45 0 ENST00000532097.1:c.648C>T p.Leu216= p.L216= ENST00000532097 NM_002817.3 216 ctC/ctT 0 +RALGAPB UCSF GRCh37 20 37150153 37150153 + synonymous_variant Silent SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 74 36 102 0 ENST00000262879.6:c.1431A>G p.Gln477= p.Q477= ENST00000262879 477 caA/caG 0 +SERPINE1 UCSF GRCh37 7 100773852 100773852 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 85 32 105 0 ENST00000223095.4:c.422G>A p.Arg141Gln p.R141Q ENST00000223095 NM_000602.4 141 cGg/cAg 0 +SMPD4 UCSF GRCh37 2 130912789 130912789 + missense_variant Missense_Mutation SNP A A C NOVEL P01_Pri Untested WXS Illumina HiSeq 14 4 14 0 ENST00000409031.1:c.1450T>G p.Phe484Val p.F484V ENST00000409031 NM_017951.4 484 Ttt/Gtt 0 +SMPD4 UCSF GRCh37 2 130912778 130912778 + synonymous_variant Silent SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 15 4 15 0 ENST00000409031.1:c.1461T>C p.Phe487= p.F487= ENST00000409031 NM_017951.4 487 ttT/ttC 0 +SRRM2 UCSF GRCh37 16 2807494 2807494 + synonymous_variant Silent SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 40 13 59 0 ENST00000301740.8:c.264G>A p.Gln88= p.Q88= ENST00000301740 NM_016333.3 88 caG/caA 0 +TEX11 UCSF GRCh37 X 69749812 69749812 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 14 16 41 0 ENST00000344304.3:c.2603T>C p.Val868Ala p.V868A ENST00000344304 868 gTc/gCc 0 +TMPRSS15 UCSF GRCh37 21 19666630 19666630 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 34 8 44 0 ENST00000284885.3:c.2443G>A p.Val815Ile p.V815I ENST00000284885 NM_002772.2 815 Gtc/Atc 0 +TP53 UCSF GRCh37 17 7578527 7578527 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 14 4 15 0 ENST00000269305.4:c.403T>C p.Cys135Arg p.C135R ENST00000269305 NM_001126112.2 135 Tgc/Cgc 0 +TP53 UCSF GRCh37 17 7579310 7579310 + splice_donor_variant Splice_Site SNP A A C NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 24 9 55 0 ENST00000269305.4:c.375+2T>G p.X125_splice ENST00000269305 NM_001126112.2 0 +TPR UCSF GRCh37 1 186301466 186301466 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 32 8 58 0 ENST00000367478.4:c.5465C>A p.Thr1822Asn p.T1822N ENST00000367478 NM_003292.2 1822 aCc/aAc 0 +TRIM33 UCSF GRCh37 1 114967346 114967346 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 28 15 59 0 ENST00000358465.2:c.1727A>G p.Gln576Arg p.Q576R ENST00000358465 NM_015906.3 576 cAa/cGa 0 +TYW1B UCSF GRCh37 7 72093896 72093896 + missense_variant Missense_Mutation SNP C C T snp132_rs7776775 P01_Pri Untested WXS Illumina HiSeq 35 4 38 1 ENST00000435769.2:c.1594G>A p.Glu532Lys p.E532K ENST00000435769 NM_001145440.1 532 Gaa/Aaa 0 +VCAN UCSF GRCh37 5 82815180 82815180 + missense_variant Missense_Mutation SNP C C A NOVEL P01_Pri Untested WXS Illumina HiSeq 43 7 57 1 ENST00000265077.3:c.1055C>A p.Thr352Lys p.T352K ENST00000265077 NM_004385.4 352 aCa/aAa 0 +WBSCR17 UCSF GRCh37 7 71175875 71175875 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 10 5 19 0 ENST00000333538.5:c.1630G>A p.Val544Ile p.V544I ENST00000333538 NM_022479.2 544 Gtc/Atc 0 +ZNF598 UCSF GRCh37 16 2048796 2048796 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.086,1000g2011may_all_0.1651,snp132_rs1058474 P01_Pri Untested WXS Illumina HiSeq 8 7 8 0 ENST00000431526.1:c.2268G>A p.Arg756= p.R756= ENST00000431526 756 agG/agA 0 +ZNF616 UCSF GRCh37 19 52620039 52620039 + missense_variant Missense_Mutation SNP A A C NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 105 19 150 0 ENST00000600228.1:c.378T>G p.His126Gln p.H126Q ENST00000600228 NM_178523.3 126 caT/caG 0 +AADAT UCSF GRCh37 4 170989794 170989794 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 24 91 0 ENST00000337664.4:c.848G>A p.Arg283Lys p.R283K ENST00000337664 NM_016228.3 283 aGa/aAa 0 +AAK1 UCSF GRCh37 2 69746264 69746264 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 13 0 ENST00000409085.4:c.1319C>T p.Pro440Leu p.P440L ENST00000409085 NM_014911.3 440 cCc/cTc 0 +ABCA2 UCSF GRCh37 9 139914833 139914833 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 7 11 0 ENST00000341511.6:c.1380C>T p.Ile460= p.I460= ENST00000341511 NM_212533.2 460 atC/atT 0 +ABCA4 UCSF GRCh37 1 94548977 94548977 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 154 34 179 0 ENST00000370225.3:c.789C>T p.Ser263= p.S263= ENST00000370225 NM_000350.2 263 agC/agT 0 +ABCA8 UCSF GRCh37 17 66914202 66914202 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 22 43 0 ENST00000269080.2:c.1913C>T p.Ala638Val p.A638V ENST00000269080 NM_007168.2 638 gCc/gTc 0 +ABCC10 UCSF GRCh37 6 43415071 43415071 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 7 23 0 ENST00000372530.4:c.3630C>T p.Ala1210= p.A1210= ENST00000372530 NM_001198934.1 1210 gcC/gcT 0 +ABCC3 UCSF GRCh37 17 48733333 48733333 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 8 16 0 ENST00000285238.8:c.186C>T p.Gly62= p.G62= ENST00000285238 NM_003786.3 62 ggC/ggT 0 +ABCC6 UCSF GRCh37 16 16281014 16281014 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 5 17 0 ENST00000205557.7:c.1834C>T p.Pro612Ser p.P612S ENST00000205557 NM_001171.5 612 Cct/Tct 0 +ABCC6 UCSF GRCh37 16 16259656 16259656 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 7 50 0 ENST00000205557.7:c.3130C>T p.Leu1044= p.L1044= ENST00000205557 NM_001171.5 1044 Ctg/Ttg 0 +ABCF1 UCSF GRCh37 6 30552213 30552213 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 53 6 21 0 ENST00000326195.8:c.1261G>A p.Ala421Thr p.A421T ENST00000326195 NM_001025091.1 421 Gcc/Acc 0 +ABCG4 UCSF GRCh37 11 119025283 119025283 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 4 22 0 ENST00000307417.3:c.538C>T p.Leu180= p.L180= ENST00000307417 NM_022169.4 180 Ctg/Ttg 0 +ABHD1 UCSF GRCh37 2 27353277 27353277 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0014 P01_Rec Untested WXS Illumina HiSeq 61 59 95 0 ENST00000316470.4:c.999C>T p.Pro333= p.P333= ENST00000316470 NM_032604.3 333 ccC/ccT 0 +ABHD14A UCSF GRCh37 3 52011925 52011925 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0106,snp132_rs34991570 P01_Rec Untested WXS Illumina HiSeq 7 33 74 0 ENST00000273596.3:c.108C>T p.Ala36= p.A36= ENST00000273596 NM_015407.4 36 gcC/gcT 0 +ABI3BP UCSF GRCh37 3 100523699 100523699 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 31 54 0 ENST00000284322.5:c.1684C>T p.Pro562Ser p.P562S ENST00000284322 NM_015429.3 562 Ccc/Tcc 0 +ABRA UCSF GRCh37 8 107781939 107781939 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 75 9 46 0 ENST00000311955.3:c.480G>A p.Arg160= p.R160= ENST00000311955 NM_139166.4 160 agG/agA 0 +ACACB UCSF GRCh37 12 109671612 109671612 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 4 28 51 0 ENST00000338432.7:c.4199G>A p.Ser1400Asn p.S1400N ENST00000338432 1400 aGc/aAc 0 +ACADSB UCSF GRCh37 10 124804002 124804002 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 5 48 0 ENST00000358776.4:c.900+1G>A p.X300_splice ENST00000358776 NM_001609.3 0 +ACCN1 UCSF GRCh37 17 32483105 32483105 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 29 38 0 ENST00000359872.6:c.447G>A p.Lys149= p.K149= ENST00000359872 NM_001094.4 149 aaG/aaA 0 +ACCN2 UCSF GRCh37 12 50473742 50473742 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 18 40 0 ENST00000447966.2:c.1109C>T p.Thr370Ile p.T370I ENST00000447966 NM_001095.3 370 aCc/aTc 0 +ACCN2 UCSF GRCh37 12 50473707 50473707 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 9 56 0 ENST00000447966.2:c.1074G>A p.Gln358= p.Q358= ENST00000447966 NM_001095.3 358 caG/caA 0 +ACHE UCSF GRCh37 7 100490086 100490086 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 11 22 0 ENST00000241069.5:c.1422G>A p.Met474Ile p.M474I ENST00000241069 NM_000665.3 474 atG/atA 0 +ACHE UCSF GRCh37 7 100491439 100491439 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 9 30 0 ENST00000241069.5:c.415C>T p.Pro139Ser p.P139S ENST00000241069 NM_000665.3 139 Cct/Tct 0 +ACIN1 UCSF GRCh37 14 23564285 23564285 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 6 17 0 ENST00000262710.1:c.211C>T p.Pro71Ser p.P71S ENST00000262710 NM_001164814.1 71 Cct/Tct 0 +ACOT7 UCSF GRCh37 1 6399581 6399581 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 3 11 0 ENST00000377855.2:c.360G>A p.Glu120= p.E120= ENST00000377855 NM_181864.2 120 gaG/gaA 0 +ACOT7 UCSF GRCh37 1 6399629 6399629 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 5 14 0 ENST00000377855.2:c.312G>A p.Leu104= p.L104= ENST00000377855 NM_181864.2 104 ctG/ctA 0 +ACOX2 UCSF GRCh37 3 58514680 58514680 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 6 47 0 ENST00000302819.5:c.996C>T p.Asp332= p.D332= ENST00000302819 NM_003500.3 332 gaC/gaT 0 +ACSF2 UCSF GRCh37 17 48551629 48551629 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 24 44 0 ENST00000300441.4:c.1797+1G>A p.X599_splice ENST00000300441 NM_025149.4 0 +ACSM2A UCSF GRCh37 16 20482518 20482518 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 13 75 0 ENST00000219054.6:c.720C>T p.Leu240= p.L240= ENST00000219054 240 ctC/ctT 0 +ACSS1 UCSF GRCh37 20 24988489 24988489 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 6 20 0 ENST00000323482.4:c.1979G>A p.Gly660Glu p.G660E ENST00000323482 NM_001252675.1 660 gGa/gAa 0 +ACTL9 UCSF GRCh37 19 8808284 8808284 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 8 9 0 ENST00000324436.3:c.768C>T p.His256= p.H256= ENST00000324436 NM_178525.3 256 caC/caT 0 +ACTR2 UCSF GRCh37 2 65478212 65478212 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 21 101 0 ENST00000260641.5:c.427G>A p.Val143Ile p.V143I ENST00000260641 NM_005722.3 143 Gtt/Att 0 +ACY3 UCSF GRCh37 11 67410218 67410218 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 18 28 0 ENST00000255082.3:c.937C>T p.Pro313Ser p.P313S ENST00000255082 NM_080658.1 313 Cct/Tct 0 +ADAM10 UCSF GRCh37 15 58889799 58889799 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 35 61 0 ENST00000260408.3:c.2194C>T p.Pro732Ser p.P732S ENST00000260408 NM_001110.2 732 Ccc/Tcc 0 +ADAM11 UCSF GRCh37 17 42850761 42850761 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 16 11 14 0 ENST00000200557.6:c.958C>T p.Leu320= p.L320= ENST00000200557 NM_002390.4 320 Ctg/Ttg 0 +ADAM11 UCSF GRCh37 17 42854295 42854295 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 26 32 0 ENST00000200557.6:c.1646C>T p.Thr549Ile p.T549I ENST00000200557 NM_002390.4 549 aCc/aTc 0 +ADAM12 UCSF GRCh37 10 127824179 127824179 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 25 0 ENST00000368679.4:c.399C>T p.Val133= p.V133= ENST00000368679 NM_003474.4 133 gtC/gtT 0 +ADAMTS15 UCSF GRCh37 11 130331452 130331452 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 17 26 0 ENST00000299164.2:c.1026G>A p.Lys342= p.K342= ENST00000299164 NM_139055.2 342 aaG/aaA 0 +ADAMTS16 UCSF GRCh37 5 5306737 5306737 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 14 50 0 ENST00000274181.7:c.3307C>T p.Leu1103= p.L1103= ENST00000274181 NM_139056.2 1103 Ctg/Ttg 0 +ADAMTSL4 UCSF GRCh37 1 150528791 150528791 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 5 19 0 ENST00000271643.4:c.1525G>A p.Gly509Arg p.G509R ENST00000271643 NM_019032.4 509 Gga/Aga 0 +ADCY8 UCSF GRCh37 8 131848647 131848647 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 9 42 0 ENST00000286355.5:c.2551C>T p.Leu851Phe p.L851F ENST00000286355 NM_001115.2 851 Ctc/Ttc 0 +ADI1 UCSF GRCh37 2 3504731 3504731 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 11 25 0 ENST00000327435.6:c.274G>A p.Asp92Asn p.D92N ENST00000327435 NM_018269.3 92 Gac/Aac 0 +ADNP2 UCSF GRCh37 18 77896524 77896524 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 28 107 0 ENST00000262198.4:c.3228G>A p.Leu1076= p.L1076= ENST00000262198 NM_014913.3 1076 ttG/ttA 0 +ADORA3 UCSF GRCh37 1 112028394 112028394 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 29 84 0 ENST00000369717.4:c.698C>T p.Thr233Ile p.T233I ENST00000369717 NM_001081976.1 233 aCc/aTc 0 +AEBP1 UCSF GRCh37 7 44151787 44151787 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 10 29 0 ENST00000223357.3:c.2084G>A p.Gly695Asp p.G695D ENST00000223357 NM_001129.4 695 gGc/gAc 0 +AFAP1 UCSF GRCh37 4 7770645 7770645 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 20 42 0 ENST00000358461.2:c.2092G>A p.Ala698Thr p.A698T ENST00000358461 NM_198595.2 698 Gcg/Acg 0 +AFAP1 UCSF GRCh37 4 7811454 7811454 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 16 70 0 ENST00000358461.2:c.941G>A p.Gly314Asp p.G314D ENST00000358461 NM_198595.2 314 gGc/gAc 0 +AFAP1L2 UCSF GRCh37 10 116059077 116059077 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 5 37 0 ENST00000304129.4:c.2055C>T p.His685= p.H685= ENST00000304129 NM_001287824.1 685 caC/caT 0 +AFF3 UCSF GRCh37 2 100627968 100627968 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 79 12 77 0 ENST00000409236.2:c.54-2574G>A *18* ENST00000409236 0 +AGBL1 UCSF GRCh37 15 86697787 86697787 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 8 44 0 ENST00000441037.2:c.251C>T p.Ser84Phe p.S84F ENST00000441037 NM_152336.2 84 tCc/tTc 0 +AGBL2 UCSF GRCh37 11 47684615 47684615 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 110 19 147 1 ENST00000525123.1:c.2498C>T p.Ala833Val p.A833V ENST00000525123 NM_024783.3 833 gCc/gTc 0 +AGER UCSF GRCh37 6 32150123 32150123 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 24 43 0 ENST00000375076.4:c.865C>T p.Pro289Ser p.P289S ENST00000375076 NM_001206929.1 289 Cct/Tct 0 +AGRN UCSF GRCh37 1 979635 979635 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 3 13 0 ENST00000379370.2:c.2146C>T p.Pro716Ser p.P716S ENST00000379370 NM_198576.3 716 Ccg/Tcg 0 +AGT UCSF GRCh37 1 230839975 230839975 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 5 27 0 ENST00000366667.4:c.1233G>A p.Leu411= p.L411= ENST00000366667 NM_000029.3 411 ctG/ctA 0 +AGXT2L1 UCSF GRCh37 4 109681017 109681017 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 9 59 0 ENST00000296486.3:c.223G>A p.Glu75Lys p.E75K ENST00000296486 NM_031279.3 75 Gaa/Aaa 0 +AHNAK UCSF GRCh37 11 62297645 62297645 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 136 70 131 0 ENST00000378024.4:c.4244G>A p.Gly1415Glu p.G1415E ENST00000378024 NM_001620.2 1415 gGa/gAa 0 +AHNAK2 UCSF GRCh37 14 105411656 105411656 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 62 98 0 ENST00000333244.5:c.10132G>A p.Glu3378Lys p.E3378K ENST00000333244 NM_138420.2 3378 Gag/Aag 0 +AHNAK2 UCSF GRCh37 14 105416524 105416524 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 80 102 0 ENST00000333244.5:c.5264C>T p.Ala1755Val p.A1755V ENST00000333244 NM_138420.2 1755 gCc/gTc 0 +AIM1L UCSF GRCh37 1 26673016 26673016 + upstream_gene_variant 5'Flank SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 8 14 0 ENST00000308182 0 +AIPL1 UCSF GRCh37 17 6330210 6330210 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 16 26 0 ENST00000381129.3:c.633G>A p.Leu211= p.L211= ENST00000381129 NM_014336.3 211 ctG/ctA 0 +AK5 UCSF GRCh37 1 78001692 78001692 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 6 48 0 ENST00000354567.2:c.1589C>T p.Ala530Val p.A530V ENST00000354567 NM_174858.2 530 gCc/gTc 0 +AKAP1 UCSF GRCh37 17 55193506 55193506 + synonymous_variant Silent SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 25 19 26 0 ENST00000337714.3:c.2316G>A p.Gly772= p.G772= ENST00000337714 NM_003488.3 772 ggG/ggA 0 +AKAP1 UCSF GRCh37 17 55183547 55183547 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 14 38 0 ENST00000337714.3:c.722G>A p.Gly241Glu p.G241E ENST00000337714 NM_003488.3 241 gGg/gAg 0 +AKAP10 UCSF GRCh37 17 19812583 19812583 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 23 59 0 ENST00000225737.6:c.1894G>A p.Glu632Lys p.E632K ENST00000225737 NM_007202.3 632 Gaa/Aaa 0 +AKAP12 UCSF GRCh37 6 151670458 151670458 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 23 64 0 ENST00000253332.1:c.932C>T p.Thr311Ile p.T311I ENST00000253332 311 aCc/aTc 0 +AKAP9 UCSF GRCh37 7 91706181 91706181 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 21 61 0 ENST00000356239.3:c.6625G>A p.Glu2209Lys p.E2209K ENST00000356239 NM_147185.2 2209 Gaa/Aaa 0 +AKNAD1 UCSF GRCh37 1 109394475 109394475 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 87 53 120 0 ENST00000370001.3:c.812C>T p.Pro271Leu p.P271L ENST00000370001 NM_152763.4 271 cCt/cTt 0 +AKR1E2 UCSF GRCh37 10 4872960 4872960 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 32 53 0 ENST00000298375.7:c.133G>A p.Glu45Lys p.E45K ENST00000298375 NM_001040177.2 45 Gag/Aag 0 +ALDH8A1 UCSF GRCh37 6 135260414 135260414 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 30 51 0 ENST00000265605.2:c.582G>A p.Leu194= p.L194= ENST00000265605 NM_022568.3 194 ctG/ctA 0 +ALDOA UCSF GRCh37 16 30080180 30080180 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 24 48 0 ENST00000338110.5:c.421G>A p.Asp141Asn p.D141N ENST00000338110 NM_000034.3 141 Gac/Aac 0 +ALDOB UCSF GRCh37 9 104192239 104192239 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 22 48 0 ENST00000374855.4:c.122G>A p.Gly41Glu p.G41E ENST00000374855 NM_000035.3 41 gGg/gAg 0 +ALG6 UCSF GRCh37 1 63894432 63894432 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 43 106 0 ENST00000371108.4:c.1087C>T p.Pro363Ser p.P363S ENST00000371108 NM_013339.3 363 Cct/Tct 0 +ALKBH3 UCSF GRCh37 11 43941489 43941489 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 39 75 0 ENST00000302708.4:c.790C>T p.His264Tyr p.H264Y ENST00000302708 NM_139178.3 264 Cac/Tac 0 +ALMS1 UCSF GRCh37 2 73679463 73679463 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 47 87 0 ENST00000264448.6:c.5806C>T p.Pro1936Ser p.P1936S ENST00000264448 NM_015120.4 1936 Cct/Tct 0 +ALMS1 UCSF GRCh37 2 73717043 73717043 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 74 51 121 0 ENST00000264448.6:c.7954C>T p.Pro2652Ser p.P2652S ENST00000264448 NM_015120.4 2652 Cca/Tca 0 +ALMS1 UCSF GRCh37 2 73830377 73830377 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 23 34 0 ENST00000264448.6:c.12305C>T p.Ala4102Val p.A4102V ENST00000264448 NM_015120.4 4102 gCt/gTt 0 +ALPK1 UCSF GRCh37 4 113333097 113333097 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 5 21 0 ENST00000177648.9:c.391G>A p.Ala131Thr p.A131T ENST00000177648 131 Gcc/Acc 0 +ALS2 UCSF GRCh37 2 202606440 202606440 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 6 30 0 ENST00000264276.6:c.2308G>A p.Val770Ile p.V770I ENST00000264276 NM_020919.3 770 Gtc/Atc 0 +AMACR UCSF GRCh37 5 33989386 33989386 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 13 44 0 ENST00000335606.6:c.961C>T p.Gln321Ter p.Q321* ENST00000335606 NM_001167595.1 321 Cag/Tag 0 +AMACR UCSF GRCh37 5 33988422 33988422 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 13 58 0 ENST00000335606.6:c.*776C>T *259* ENST00000335606 NM_001167595.1 0 +AMBRA1 UCSF GRCh37 11 46569868 46569868 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 84 54 124 0 ENST00000458649.2:c.63G>A p.Arg21= p.R21= ENST00000458649 21 cgG/cgA 0 +AMFR UCSF GRCh37 16 56419852 56419852 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 9 21 0 ENST00000290649.5:c.1359C>T p.Ser453= p.S453= ENST00000290649 NM_001144.5 453 agC/agT 0 +AMMECR1 UCSF GRCh37 X 109507796 109507796 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 13 44 0 ENST00000262844.5:c.505G>A p.Asp169Asn p.D169N ENST00000262844 NM_015365.2 169 Gac/Aac 0 +AMOT UCSF GRCh37 X 112065871 112065871 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 9 29 0 ENST00000371959.3:c.484G>A p.Gly162Arg p.G162R ENST00000371959 NM_001113490.1 162 Gga/Aga 0 +AMY2B UCSF GRCh37 1 104120231 104120231 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 120 69 255 0 ENST00000361355.4:c.1220+1G>A p.X407_splice ENST00000361355 NM_020978.4 0 +AMZ1 UCSF GRCh37 7 2752379 2752379 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 10 9 0 ENST00000312371.4:c.1364C>T p.Pro455Leu p.P455L ENST00000312371 NM_133463.1 455 cCc/cTc 0 +ANK1 UCSF GRCh37 8 41552836 41552836 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 9 26 0 ENST00000347528.4:c.2974G>A p.Glu992Lys p.E992K ENST00000347528 NM_020477.2 992 Gag/Aag 0 +ANK1 UCSF GRCh37 8 41542129 41542129 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 3 22 0 ENST00000347528.4:c.4470C>T p.Ser1490= p.S1490= ENST00000347528 NM_020477.2 1490 agC/agT 0 +ANK2 UCSF GRCh37 4 114239724 114239724 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 6 28 0 ENST00000357077.4:c.2848G>A p.Gly950Ser p.G950S ENST00000357077 NM_001148.4 950 Ggc/Agc 0 +ANK2 UCSF GRCh37 4 114275995 114275995 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 111 20 90 0 ENST00000357077.4:c.6221G>A p.Gly2074Glu p.G2074E ENST00000357077 NM_001148.4 2074 gGa/gAa 0 +ANK3 UCSF GRCh37 10 61829559 61829559 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 31 38 0 ENST00000280772.2:c.11080G>A p.Glu3694Lys p.E3694K ENST00000280772 NM_020987.3 3694 Gaa/Aaa 0 +ANK3 UCSF GRCh37 10 61830291 61830291 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 37 69 0 ENST00000280772.2:c.10348G>A p.Gly3450Ser p.G3450S ENST00000280772 NM_020987.3 3450 Ggc/Agc 0 +ANKRD13C UCSF GRCh37 1 70819825 70819825 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 14 24 0 ENST00000370944.4:c.267C>T p.Ser89= p.S89= ENST00000370944 NM_030816.4 89 tcC/tcT 0 +ANKRD18B UCSF GRCh37 9 33548687 33548687 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 86 58 104 0 ENST00000290943.6:c.1715C>T p.Ala572Val p.A572V ENST00000290943 NM_001244752.1 572 gCt/gTt 0 +ANKRD30A UCSF GRCh37 10 37486358 37486358 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 111 19 135 0 ENST00000361713.1:c.2498C>T p.Ser833Phe p.S833F ENST00000361713 NM_052997.2 833 tCt/tTt 0 +ANKRD35 UCSF GRCh37 1 145562121 145562121 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 14 30 0 ENST00000355594.4:c.1809G>A p.Lys603= p.K603= ENST00000355594 NM_144698.4 603 aaG/aaA 0 +ANKRD5 UCSF GRCh37 20 10030860 10030860 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 20 64 0 ENST00000378380.3:c.1643G>A p.Gly548Glu p.G548E ENST00000378380 NM_198798.1 548 gGa/gAa 0 +ANKRD54 UCSF GRCh37 22 38228727 38228727 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 5 22 0 ENST00000215941.4:c.745C>T p.Leu249= p.L249= ENST00000215941 NM_138797.2 249 Ctg/Ttg 0 +ANKS1B UCSF GRCh37 12 99166907 99166907 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 26 113 0 ENST00000547776.2:c.3417C>T p.Asp1139= p.D1139= ENST00000547776 NM_152788.4 1139 gaC/gaT 0 +ANO3 UCSF GRCh37 11 26556003 26556003 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 19 44 0 ENST00000256737.3:c.870C>T p.His290= p.H290= ENST00000256737 NM_031418.2 290 caC/caT 0 +ANO7 UCSF GRCh37 2 242138787 242138787 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 5 18 0 ENST00000274979.8:c.528G>A p.Trp176Ter p.W176* ENST00000274979 NM_001001891.3 176 tgG/tgA 0 +ANTXR2 UCSF GRCh37 4 80905121 80905121 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 80 20 109 0 ENST00000307333.7:c.1090G>A p.Glu364Lys p.E364K ENST00000307333 NM_001145794.1 364 Gaa/Aaa 0 +AP3D1 UCSF GRCh37 19 2129445 2129445 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 5 21 0 ENST00000345016.5:c.604G>A p.Ala202Thr p.A202T ENST00000345016 NM_003938.6 202 Gct/Act 0 +AP4E1 UCSF GRCh37 15 51250900 51250900 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 135 26 147 0 ENST00000261842.5:c.1760G>A p.Arg587Lys p.R587K ENST00000261842 NM_001252127.1 587 aGa/aAa 0 +APEH UCSF GRCh37 3 49720324 49720324 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 15 26 0 ENST00000296456.5:c.1932C>T p.Asp644= p.D644= ENST00000296456 NM_001640.3 644 gaC/gaT 0 +APIP UCSF GRCh37 11 34916587 34916587 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 91 11 65 0 ENST00000395787.3:c.128G>A p.Gly43Glu p.G43E ENST00000395787 NM_015957.2 43 gGg/gAg 0 +APOBEC3H UCSF GRCh37 22 39497501 39497501 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 7 18 0 ENST00000401756.1:c.410G>A p.Gly137Asp p.G137D ENST00000401756 NM_001166003.1 137 gGc/gAc 0 +APOO UCSF GRCh37 X 23897071 23897071 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 3 21 16 0 ENST00000379226.4:c.198G>A p.Gln66= p.Q66= ENST00000379226 NM_024122.4 66 caG/caA 0 +APPL2 UCSF GRCh37 12 105591584 105591584 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 11 34 0 ENST00000258530.3:c.1011C>T p.Asp337= p.D337= ENST00000258530 NM_001251904.1 337 gaC/gaT 0 +ARAP3 UCSF GRCh37 5 141033770 141033770 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 13 17 0 ENST00000239440.4:c.4382G>A p.Arg1461Lys p.R1461K ENST00000239440 NM_022481.5 1461 aGg/aAg 0 +ARFGAP3 UCSF GRCh37 22 43243638 43243638 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 8 106 0 ENST00000263245.5:c.70G>A p.Val24Met p.V24M ENST00000263245 NM_014570.4 24 Gtg/Atg 0 +ARHGAP21 UCSF GRCh37 10 24874187 24874187 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 89 54 164 0 ENST00000396432.2:c.5031C>T p.Thr1677= p.T1677= ENST00000396432 NM_020824.3 1677 acC/acT 0 +ARHGAP28 UCSF GRCh37 18 6896545 6896545 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 8 57 0 ENST00000383472.4:c.1950C>T p.Leu650= p.L650= ENST00000383472 650 ctC/ctT 0 +ARHGAP30 UCSF GRCh37 1 161024235 161024235 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 19 0 ENST00000368013.3:c.457G>A p.Val153Ile p.V153I ENST00000368013 NM_181720.2 153 Gta/Ata 0 +ARHGAP35 UCSF GRCh37 19 47425094 47425094 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 25 92 0 ENST00000404338.3:c.3162G>A p.Gly1054= p.G1054= ENST00000404338 NM_004491.4 1054 ggG/ggA 0 +ARHGAP42 UCSF GRCh37 11 100847606 100847606 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 35 60 0 ENST00000298815.8:c.2297C>T p.Pro766Leu p.P766L ENST00000298815 NM_152432.2 766 cCc/cTc 0 +ARHGDIA UCSF GRCh37 17 79827721 79827721 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 3 13 0 ENST00000269321.7:c.86C>T p.Pro29Leu p.P29L ENST00000269321 NM_001185078.1 29 cCc/cTc 0 +ARHGEF15 UCSF GRCh37 17 8218574 8218574 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 11 21 0 ENST00000361926.3:c.1239C>T p.Pro413= p.P413= ENST00000361926 NM_173728.3 413 ccC/ccT 0 +ARHGEF2 UCSF GRCh37 1 155931569 155931569 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 18 35 0 ENST00000361247.4:c.1351C>T p.Pro451Ser p.P451S ENST00000361247 NM_001162384.1 451 Cct/Tct 0 +ARHGEF33 UCSF GRCh37 2 39193159 39193159 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 88 41 107 0 ENST00000409978.1:c.2356G>A p.Glu786Lys p.E786K ENST00000409978 786 Gaa/Aaa 0 +ARHGEF40 UCSF GRCh37 14 21543874 21543874 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 9 18 0 ENST00000298694.4:c.1689C>T p.Pro563= p.P563= ENST00000298694 NM_001278529.1 563 ccC/ccT 0 +ARHGEF6 UCSF GRCh37 X 135767925 135767925 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 8 77 0 ENST00000250617.6:c.1303C>T p.Pro435Ser p.P435S ENST00000250617 NM_004840.2 435 Cct/Tct 0 +ARID1A UCSF GRCh37 1 27106143 27106143 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 41 74 0 ENST00000324856.7:c.5754G>A p.Arg1918= p.R1918= ENST00000324856 NM_006015.4 1918 cgG/cgA 0 +ARID4B UCSF GRCh37 1 235386532 235386532 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 42 0 ENST00000264183.3:c.1014G>A p.Leu338= p.L338= ENST00000264183 NM_016374.5 338 ttG/ttA 0 +ARID5B UCSF GRCh37 10 63851799 63851799 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 112 16 113 1 ENST00000279873.7:c.2577G>A p.Arg859= p.R859= ENST00000279873 NM_032199.2 859 agG/agA 0 +ARNT2 UCSF GRCh37 15 80845102 80845102 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 56 107 0 ENST00000303329.4:c.1076G>A p.Gly359Asp p.G359D ENST00000303329 NM_014862.3 359 gGc/gAc 0 +ARSI UCSF GRCh37 5 149677350 149677350 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 4 19 0 ENST00000328668.7:c.1137G>A p.Glu379= p.E379= ENST00000328668 NM_001012301.2 379 gaG/gaA 0 +ART5 UCSF GRCh37 11 3661212 3661212 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 5 22 51 0 ENST00000359918.4:c.447C>T p.Gly149= p.G149= ENST00000359918 NM_001079536.1 149 ggC/ggT 0 +ASAP2 UCSF GRCh37 2 9496363 9496363 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 115 17 72 0 ENST00000281419.3:c.1216G>A p.Gly406Arg p.G406R ENST00000281419 NM_003887.2 406 Ggg/Agg 0 +ASAP3 UCSF GRCh37 1 23758293 23758293 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 14 36 0 ENST00000336689.3:c.2442C>T p.Ala814= p.A814= ENST00000336689 NM_017707.3 814 gcC/gcT 0 +ASCC3 UCSF GRCh37 6 101053571 101053571 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 22 67 0 ENST00000369162.2:c.5050C>T p.Leu1684Phe p.L1684F ENST00000369162 NM_006828.2 1684 Ctc/Ttc 0 +ASGR2 UCSF GRCh37 17 7017555 7017555 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 15 35 0 ENST00000355035.5:c.5C>T p.Ala2Val p.A2V ENST00000355035 2 gCc/gTc 0 +ASGR2 UCSF GRCh37 17 7010367 7010367 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 7 34 0 ENST00000355035.5:c.615C>T p.Cys205= p.C205= ENST00000355035 205 tgC/tgT 0 +ASNA1 UCSF GRCh37 19 12858848 12858849 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P01_Rec Untested WXS Illumina HiSeq 6 0 ENST00000357332.3:c.982dup p.Ala328GlyfsTer90 p.A328Gfs*90 ENST00000357332 NM_004317.2 326 cgg/cgGg 0 +ASNA1 UCSF GRCh37 19 12858790 12858790 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 9 28 0 ENST00000357332.3:c.919G>A p.Glu307Lys p.E307K ENST00000357332 NM_004317.2 307 Gag/Aag 0 +ASNS UCSF GRCh37 7 97488694 97488694 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 25 66 0 ENST00000175506.4:c.504G>A p.Lys168= p.K168= ENST00000175506 NM_183356.3 168 aaG/aaA 0 +ASPM UCSF GRCh37 1 197102528 197102528 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 30 60 0 ENST00000367409.4:c.2371G>A p.Ala791Thr p.A791T ENST00000367409 NM_018136.4 791 Gct/Act 0 +ASPM UCSF GRCh37 1 197104229 197104229 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 13 50 0 ENST00000367409.4:c.2170G>A p.Glu724Lys p.E724K ENST00000367409 NM_018136.4 724 Gaa/Aaa 0 +ASTL UCSF GRCh37 2 96795688 96795688 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 6 24 0 ENST00000342380.2:c.749C>T p.Thr250Ile p.T250I ENST00000342380 NM_001002036.3 250 aCc/aTc 0 +ASTN2 UCSF GRCh37 9 119203066 119203066 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 35 70 0 ENST00000313400.4:c.3604G>A p.Ala1202Thr p.A1202T ENST00000313400 1202 Gct/Act 0 +ATE1 UCSF GRCh37 10 123600639 123600639 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 19 44 0 ENST00000224652.6:c.1115C>T p.Pro372Leu p.P372L ENST00000224652 NM_001001976.1 372 cCt/cTt 0 +ATF6B UCSF GRCh37 6 32085767 32085767 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 14 25 0 ENST00000375203.3:c.1293G>A p.Gly431= p.G431= ENST00000375203 NM_001136153.1 431 ggG/ggA 0 +ATG13 UCSF GRCh37 11 46671758 46671758 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 42 75 0 ENST00000359513.4:c.349G>A p.Val117Met p.V117M ENST00000359513 117 Gtg/Atg 0 +ATM UCSF GRCh37 11 108165786 108165786 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 77 48 143 0 ENST00000278616.4:c.4909G>A p.Asp1637Asn p.D1637N ENST00000278616 NM_000051.3 1637 Gat/Aat 0 +ATN1 UCSF GRCh37 12 7046299 7046299 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 12 38 0 ENST00000356654.4:c.1869C>T p.Ser623= p.S623= ENST00000356654 NM_001007026.1 623 tcC/tcT 0 +ATP10D UCSF GRCh37 4 47583992 47583992 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 39 83 0 ENST00000273859.3:c.3664G>A p.Asp1222Asn p.D1222N ENST00000273859 NM_020453.3 1222 Gat/Aat 0 +ATP10D UCSF GRCh37 4 47514620 47514620 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 62 0 ENST00000273859.3:c.63G>A p.Arg21= p.R21= ENST00000273859 NM_020453.3 21 agG/agA 0 +ATP1A4 UCSF GRCh37 1 160136342 160136342 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 6 46 0 ENST00000368081.4:c.1072C>T p.Arg358Cys p.R358C ENST00000368081 NM_144699.3 358 Cgc/Tgc 0 +ATP5J2-PTCD1 UCSF GRCh37 7 99017752 99017752 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 35 58 0 ENST00000292478.4:c.1941C>T p.Tyr647= p.Y647= ENST00000292478 NM_015545.3 647 taC/taT 0 +ATP6AP1L UCSF GRCh37 5 81608429 81608429 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 38 125 0 ENST00000380167.4:c.132-1G>A p.X44_splice ENST00000380167 0 +ATP6V0A1 UCSF GRCh37 17 40652850 40652850 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 63 103 0 ENST00000343619.4:c.1805C>T p.Ser602Phe p.S602F ENST00000343619 NM_001130021.1 602 tCt/tTt 0 +ATP8B4 UCSF GRCh37 15 50168672 50168672 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 29 58 0 ENST00000284509.6:c.2830G>A p.Gly944Arg p.G944R ENST00000284509 NM_024837.3 944 Gga/Aga 0 +ATP9B UCSF GRCh37 18 77133916 77133916 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 11 28 0 ENST00000426216.2:c.3089G>A p.Gly1030Glu p.G1030E ENST00000426216 NM_198531.3 1030 gGg/gAg 0 +ATRX UCSF GRCh37 X 76938230 76938231 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Rec Untested WXS Illumina HiSeq 92 0 ENST00000373344.5:c.2518dup p.Arg840LysfsTer9 p.R840Kfs*9 ENST00000373344 NM_000489.3 839 -/A 0 +ATXN2L UCSF GRCh37 16 28841357 28841357 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 4 11 0 ENST00000336783.4:c.1012G>A p.Glu338Lys p.E338K ENST00000336783 NM_007245.3 338 Gag/Aag 0 +ATXN7L1 UCSF GRCh37 7 105279975 105279975 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 29 79 0 ENST00000419735.3:c.904C>T p.Pro302Ser p.P302S ENST00000419735 NM_020725.1 302 Ccc/Tcc 0 +AUTS2 UCSF GRCh37 7 70228160 70228160 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 11 11 0 ENST00000342771.4:c.1047G>A p.Gln349= p.Q349= ENST00000342771 NM_015570.2 349 caG/caA 0 +AVPR2 UCSF GRCh37 X 153171289 153171289 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 2 17 11 0 ENST00000337474.5:c.329C>T p.Ala110Val p.A110V ENST00000337474 NM_001146151.1 110 gCc/gTc 0 +AXDND1 UCSF GRCh37 1 179364322 179364322 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 127 154 0 ENST00000367618.3:c.1094C>T p.Ala365Val p.A365V ENST00000367618 NM_144696.5 365 gCg/gTg 0 +B4GALNT4 UCSF GRCh37 11 373242 373242 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 5 34 0 ENST00000329962.6:c.587G>A p.Ser196Asn p.S196N ENST00000329962 NM_178537.4 196 aGt/aAt 0 +B7H6 UCSF GRCh37 11 17378221 17378221 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 16 33 0 ENST00000338965.4:c.94G>A p.Ala32Thr p.A32T ENST00000338965 NM_001202439.1 32 Gca/Aca 0 +BATF UCSF GRCh37 14 76012859 76012859 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 13 0 ENST00000286639.6:c.223C>T p.Leu75Phe p.L75F ENST00000286639 NM_006399.3 75 Ctc/Ttc 0 +BAZ1A UCSF GRCh37 14 35262103 35262103 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 82 16 76 0 ENST00000360310.1:c.1388G>A p.Gly463Glu p.G463E ENST00000360310 NM_013448.2 463 gGa/gAa 0 +BBS10 UCSF GRCh37 12 76740484 76740484 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 23 98 0 ENST00000393262.3:c.1281C>T p.Asp427= p.D427= ENST00000393262 NM_024685.3 427 gaC/gaT 0 +BBX UCSF GRCh37 3 107435664 107435664 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 35 68 0 ENST00000325805.8:c.373G>A p.Glu125Lys p.E125K ENST00000325805 125 Gaa/Aaa 0 +BCAS1 UCSF GRCh37 20 52644934 52644934 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 79 58 89 0 ENST00000395961.3:c.720G>A p.Gly240= p.G240= ENST00000395961 NM_003657.2 240 ggG/ggA 0 +BCLAF1 UCSF GRCh37 6 136599392 136599392 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 213 46 206 0 ENST00000531224.1:c.627C>T p.Ser209= p.S209= ENST00000531224 NM_001077441.1 209 tcC/tcT 0 +BCO2 UCSF GRCh37 11 112050076 112050076 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 91 16 136 0 ENST00000357685.5:c.164C>T p.Ala55Val p.A55V ENST00000357685 55 gCa/gTa 0 +BCO2 UCSF GRCh37 11 112064368 112064368 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0021 P01_Rec Untested WXS Illumina HiSeq 43 7 61 0 ENST00000357685.5:c.465G>A p.Lys155= p.K155= ENST00000357685 155 aaG/aaA 0 +BCOR UCSF GRCh37 X 39931725 39931725 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 6 14 0 ENST00000378444.4:c.2874G>A p.Lys958= p.K958= ENST00000378444 NM_001123385.1 958 aaG/aaA 0 +BDP1 UCSF GRCh37 5 70763227 70763227 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 108 53 185 0 ENST00000358731.4:c.832G>A p.Glu278Lys p.E278K ENST00000358731 NM_018429.2 278 Gaa/Aaa 0 +BDP1 UCSF GRCh37 5 70811923 70811923 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 26 25 45 0 ENST00000358731.4:c.4685A>G p.Lys1562Arg p.K1562R ENST00000358731 NM_018429.2 1562 aAg/aGg 0 +BDP1 UCSF GRCh37 5 70806948 70806948 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 28 150 0 ENST00000358731.4:c.4029C>T p.Asp1343= p.D1343= ENST00000358731 NM_018429.2 1343 gaC/gaT 0 +BEND2 UCSF GRCh37 X 18183254 18183254 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 66 11 49 0 ENST00000380033.4:c.2275C>T p.Arg759Cys p.R759C ENST00000380033 NM_153346.4 759 Cgt/Tgt 0 +BIRC2 UCSF GRCh37 11 102234398 102234398 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 14 48 0 ENST00000227758.2:c.1075-1G>A p.X359_splice ENST00000227758 NM_001166.4 0 +BIVM UCSF GRCh37 13 103492195 103492195 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 47 103 0 ENST00000257336.1:c.1492G>A p.Asp498Asn p.D498N ENST00000257336 NM_017693.3 498 Gat/Aat 0 +BMPER UCSF GRCh37 7 34125416 34125416 + missense_variant Missense_Mutation SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 24 9 33 0 ENST00000297161.2:c.1457C>G p.Ala486Gly p.A486G ENST00000297161 NM_133468.4 486 gCg/gGg 0 +BMS1 UCSF GRCh37 10 43294010 43294010 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 38 64 0 ENST00000374518.5:c.2184G>A p.Lys728= p.K728= ENST00000374518 NM_014753.3 728 aaG/aaA 0 +BOLL UCSF GRCh37 2 198631273 198631273 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 33 16 47 0 ENST00000392296.4:c.535C>T p.Pro179Ser p.P179S ENST00000392296 NM_033030.5 179 Cct/Tct 0 +BPGM UCSF GRCh37 7 134346330 134346330 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 32 68 0 ENST00000344924.3:c.71G>A p.Ser24Asn p.S24N ENST00000344924 NM_001724.4 24 aGc/aAc 0 +BPGM UCSF GRCh37 7 134346538 134346538 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 16 36 0 ENST00000344924.3:c.279G>A p.Gly93= p.G93= ENST00000344924 NM_001724.4 93 ggG/ggA 0 +BPIFA1 UCSF GRCh37 20 31829272 31829272 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 58 48 66 0 ENST00000354297.4:c.663C>T p.Gly221= p.G221= ENST00000354297 NM_130852.2 221 ggC/ggT 0 +BPIFB2 UCSF GRCh37 20 31606597 31606597 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 19 29 0 ENST00000170150.3:c.824G>A p.Gly275Asp p.G275D ENST00000170150 NM_025227.2 275 gGt/gAt 0 +BRE UCSF GRCh37 2 28464226 28464226 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 16 58 0 ENST00000342045.2:c.817G>A p.Glu273Lys p.E273K ENST00000342045 NM_199194.2 273 Gag/Aag 0 +BRIP1 UCSF GRCh37 17 59878736 59878736 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 128 59 172 0 ENST00000259008.2:c.1018C>T p.Leu340Phe p.L340F ENST00000259008 NM_032043.2 340 Ctt/Ttt 0 +BRIX1 UCSF GRCh37 5 34925341 34925341 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 16 12 31 0 ENST00000336767.5:c.803T>C p.Val268Ala p.V268A ENST00000336767 NM_018321.3 268 gTc/gCc 0 +BSCL2 UCSF GRCh37 11 62457979 62457979 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 8 35 0 ENST00000403550.1:c.1057G>A p.Glu353Lys p.E353K ENST00000403550 353 Gaa/Aaa 0 +BTN2A1 UCSF GRCh37 6 26459959 26459959 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 23 53 0 ENST00000312541.5:c.333C>T p.Val111= p.V111= ENST00000312541 NM_007049.4 111 gtC/gtT 0 +BTNL8 UCSF GRCh37 5 180376987 180376987 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 33 26 0 ENST00000340184.4:c.946C>T p.Gln316Ter p.Q316* ENST00000340184 NM_001040462.2 316 Cag/Tag 0 +BZRAP1 UCSF GRCh37 17 56384227 56384227 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 9 48 0 ENST00000343736.4:c.5086C>T p.Pro1696Ser p.P1696S ENST00000343736 1696 Cct/Tct 0 +BZRAP1 UCSF GRCh37 17 56395646 56395646 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 6 27 0 ENST00000343736.4:c.1867C>T p.Pro623Ser p.P623S ENST00000343736 623 Cct/Tct 0 +C10orf12 UCSF GRCh37 10 98744633 98744633 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 32 112 0 ENST00000286067.2:c.3486G>A p.Arg1162= p.R1162= ENST00000286067 NM_015652.2 1162 agG/agA 0 +C10orf120 UCSF GRCh37 10 124457495 124457496 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Rec Untested WXS Illumina HiSeq 8 0 ENST00000329446.4:c.762dup p.Cys255MetfsTer8 p.C255Mfs*8 ENST00000329446 NM_001010912.2 254 aaa/aaAa 0 +C10orf2 UCSF GRCh37 10 102748828 102748828 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 110 20 76 0 ENST00000311916.2:c.861G>A p.Thr287= p.T287= ENST00000311916 NM_021830.4 287 acG/acA 0 +C10orf28 UCSF GRCh37 10 99968816 99968816 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 64 110 0 ENST00000298999.3:c.945C>T p.Ile315= p.I315= ENST00000298999 NM_014472.4 315 atC/atT 0 +C10orf92 UCSF GRCh37 10 134628221 134628221 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 2 14 20 0 ENST00000368586.5:c.7218C>T p.Asp2406= p.D2406= ENST00000368586 NM_001200049.2 2406 gaC/gaT 0 +C11orf41 UCSF GRCh37 11 33604909 33604909 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 8 32 0 ENST00000321505.4:c.3537C>T p.Asn1179= p.N1179= ENST00000321505 1179 aaC/aaT 0 +C11orf80 UCSF GRCh37 11 66571660 66571660 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 25 96 0 ENST00000525908.1:c.890C>T p.Ser297Phe p.S297F ENST00000525908 297 tCc/tTc 0 +C14orf159 UCSF GRCh37 14 91681764 91681764 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 15 52 0 ENST00000428926.2:c.1565G>A p.Gly522Glu p.G522E ENST00000428926 NM_024952.6 522 gGa/gAa 0 +C14orf159 UCSF GRCh37 14 91681784 91681784 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0069,snp132_rs115874122 P01_Rec Untested WXS Illumina HiSeq 25 15 51 0 ENST00000428926.2:c.1585G>A p.Ala529Thr p.A529T ENST00000428926 NM_024952.6 529 Gca/Aca 0 +C14orf183 UCSF GRCh37 14 50558224 50558224 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 4 22 0 ENST00000305273.1:c.344C>T p.Ser115Phe p.S115F ENST00000305273 NM_001014830.1 115 tCc/tTc 0 +C15orf55 UCSF GRCh37 15 34640190 34640190 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 29 44 0 ENST00000333756.4:c.37G>A p.Asp13Asn p.D13N ENST00000333756 NM_175741.1 13 Gat/Aat 0 +C17orf57 UCSF GRCh37 17 45479557 45479557 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 13 65 0 ENST00000331493.2:c.2005G>A p.Ala669Thr p.A669T ENST00000331493 NM_152347.4 669 Gcc/Acc 0 +C17orf90 UCSF GRCh37 17 79632460 79632460 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 8 19 0 ENST00000374741.3:c.215G>A p.Gly72Asp p.G72D ENST00000374741 NM_001039842.1 72 gGc/gAc 0 +C18orf1 UCSF GRCh37 18 13645276 13645276 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 27 55 0 ENST00000359446.5:c.541C>T p.Pro181Ser p.P181S ENST00000359446 NM_181481.4 181 Cct/Tct 0 +C18orf34 UCSF GRCh37 18 30913143 30913143 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P01_Rec Untested WXS Illumina HiSeq 6 0 ENST00000383096.3:c.874delA p.Met292TrpfsTer3 p.M292Wfs*3 ENST00000383096 292 Atg/tg 0 +C18orf34 UCSF GRCh37 18 30803094 30803094 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 44 148 0 ENST00000383096.3:c.1908C>T p.Thr636= p.T636= ENST00000383096 636 acC/acT 0 +C18orf55 UCSF GRCh37 18 71816298 71816298 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 59 31 76 0 ENST00000169551.6:c.255G>A p.Val85= p.V85= ENST00000169551 NM_014177.2 85 gtG/gtA 0 +C1GALT1 UCSF GRCh37 7 7278542 7278542 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 15 53 0 ENST00000223122.3:c.877C>T p.Pro293Ser p.P293S ENST00000223122 293 Cct/Tct 0 +C1orf112 UCSF GRCh37 1 169773349 169773349 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 112 26 121 0 ENST00000286031.6:c.446A>G p.Asp149Gly p.D149G ENST00000286031 NM_018186.2 149 gAt/gGt 0 +C1orf116 UCSF GRCh37 1 207196449 207196449 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 13 42 0 ENST00000359470.5:c.660G>A p.Gly220= p.G220= ENST00000359470 NM_023938.5 220 ggG/ggA 0 +C1orf87 UCSF GRCh37 1 60505800 60505800 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.00092 P01_Rec Untested WXS Illumina HiSeq 76 34 81 0 ENST00000371201.3:c.536C>T p.Ala179Val p.A179V ENST00000371201 NM_152377.2 179 gCc/gTc 0 +C1orf95 UCSF GRCh37 1 226784582 226784582 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 28 45 0 ENST00000366788.3:c.282G>A p.Trp94Ter p.W94* ENST00000366788 NM_001003665.3 94 tgG/tgA 0 +C1QTNF2 UCSF GRCh37 5 159776608 159776608 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 4 38 0 ENST00000393975.3:c.560G>A p.Ser187Asn p.S187N ENST00000393975 NM_031908.4 187 aGc/aAc 0 +C1S UCSF GRCh37 12 7172489 7172489 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 16 84 0 ENST00000328916.3:c.603G>A p.Arg201= p.R201= ENST00000328916 NM_201442.2 201 agG/agA 0 +C20orf12 UCSF GRCh37 20 18395058 18395058 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 27 55 0 ENST00000262547.5:c.1176C>T p.Ser392= p.S392= ENST00000262547 NM_001099407.1 392 tcC/tcT 0 +C20orf12 UCSF GRCh37 20 18371103 18371103 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 14 67 0 ENST00000262547.5:c.1810C>T p.Pro604Ser p.P604S ENST00000262547 NM_001099407.1 604 Cct/Tct 0 +C20orf194 UCSF GRCh37 20 3251135 3251135 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 23 43 0 ENST00000252032.9:c.2724C>T p.Ser908= p.S908= ENST00000252032 NM_001009984.2 908 agC/agT 0 +C21orf7 UCSF GRCh37 21 30464779 30464779 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 40 73 0 ENST00000286791.5:c.247G>A p.Ala83Thr p.A83T ENST00000286791 83 Gca/Aca 0 +C22orf29 UCSF GRCh37 22 19839596 19839596 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 13 23 0 ENST00000328554.4:c.189G>A p.Glu63= p.E63= ENST00000328554 NM_024627.5 63 gaG/gaA 0 +C2CD3 UCSF GRCh37 11 73825484 73825484 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 17 21 0 ENST00000334126.7:c.1675C>T p.Pro559Ser p.P559S ENST00000334126 NM_001286577.1 559 Cct/Tct 0 +C3orf20 UCSF GRCh37 3 14724457 14724457 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 17 33 0 ENST00000253697.3:c.237G>A p.Val79= p.V79= ENST00000253697 NM_032137.4 79 gtG/gtA 0 +C3orf39 UCSF GRCh37 3 43121858 43121858 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 8 24 0 ENST00000344697.2:c.1066C>T p.Pro356Ser p.P356S ENST00000344697 NM_032806.5 356 Ccc/Tcc 0 +C3orf54 UCSF GRCh37 3 49842058 49842058 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 3 21 0 ENST00000333323.4:c.502G>A p.Glu168Lys p.E168K ENST00000333323 NM_203370.1 168 Gaa/Aaa 0 +C3orf55 UCSF GRCh37 3 157289050 157289050 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 15 27 0 ENST00000449199.2:c.168G>A p.Leu56= p.L56= ENST00000449199 NM_001130002.2 56 ctG/ctA 0 +C3orf77 UCSF GRCh37 3 44285883 44285883 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P01_Rec Untested WXS Illumina HiSeq 17 0 ENST00000309765.4:c.1893del p.Ala632LeufsTer5 p.A632Lfs*5 ENST00000309765 NM_001145030.1 629 Aaa/aa 0 +C3orf77 UCSF GRCh37 3 44285367 44285367 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 23 116 0 ENST00000309765.4:c.1369C>T p.Pro457Ser p.P457S ENST00000309765 NM_001145030.1 457 Cct/Tct 0 +C3orf77 UCSF GRCh37 3 44286639 44286639 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 39 85 0 ENST00000309765.4:c.2641G>A p.Glu881Lys p.E881K ENST00000309765 NM_001145030.1 881 Gag/Aag 0 +C4orf19 UCSF GRCh37 4 37592527 37592527 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 24 44 0 ENST00000284437.6:c.850G>A p.Asp284Asn p.D284N ENST00000284437 NM_018302.2 284 Gat/Aat 0 +C4orf6 UCSF GRCh37 4 5527144 5527144 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 26 38 0 ENST00000195455.2:c.87G>A p.Gly29= p.G29= ENST00000195455 NM_005750.2 29 ggG/ggA 0 +C5 UCSF GRCh37 9 123734242 123734242 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 16 43 0 ENST00000223642.1:c.4046G>A p.Ser1349Asn p.S1349N ENST00000223642 NM_001735.2 1349 aGt/aAt 0 +C5 UCSF GRCh37 9 123783936 123783936 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 112 48 83 0 ENST00000223642.1:c.1153G>A p.Gly385Arg p.G385R ENST00000223642 NM_001735.2 385 Gga/Aga 0 +C5orf42 UCSF GRCh37 5 37125417 37125417 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 118 32 142 0 ENST00000425232.2:c.8725G>A p.Ala2909Thr p.A2909T ENST00000425232 NM_023073.3 2909 Gca/Aca 0 +C5orf43 UCSF GRCh37 5 60455983 60455983 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 16 73 0 ENST00000339020.3:c.16G>A p.Ala6Thr p.A6T ENST00000339020 NM_001048249.3 6 Gct/Act 0 +C6orf204 UCSF GRCh37 6 118832578 118832578 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 26 76 1 ENST00000368491.3:c.1140G>A p.Arg380= p.R380= ENST00000368491 NM_001042475.2 380 cgG/cgA 0 +C6orf58 UCSF GRCh37 6 127899845 127899845 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 83 46 101 0 ENST00000329722.7:c.316C>T p.Pro106Ser p.P106S ENST00000329722 NM_001010905.2 106 Cca/Tca 0 +C7 UCSF GRCh37 5 40958327 40958327 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 29 68 0 ENST00000313164.9:c.1453G>A p.Ala485Thr p.A485T ENST00000313164 NM_000587.2 485 Gcg/Acg 0 +C7 UCSF GRCh37 5 40979915 40979915 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 73 18 69 0 ENST00000313164.9:c.2254G>A p.Gly752Ser p.G752S ENST00000313164 NM_000587.2 752 Ggt/Agt 0 +C7orf42 UCSF GRCh37 7 66416123 66416123 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 29 29 0 ENST00000341567.4:c.780+1G>A p.X260_splice ENST00000341567 NM_017994.4 0 +C7orf61 UCSF GRCh37 7 100061155 100061155 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 20 39 0 ENST00000332375.3:c.218C>T p.Ser73Phe p.S73F ENST00000332375 NM_001004323.1 73 tCc/tTc 0 +C8B UCSF GRCh37 1 57395081 57395081 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 20 46 0 ENST00000371237.4:c.1772C>T p.Ser591Phe p.S591F ENST00000371237 NM_000066.3 591 tCc/tTc 0 +C9orf102 UCSF GRCh37 9 98678678 98678678 + missense_variant Missense_Mutation SNP A A T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 28 71 0 ENST00000288985.7:c.1153A>T p.Thr385Ser p.T385S ENST00000288985 NM_001010895.2 385 Act/Tct 0 +C9orf135 UCSF GRCh37 9 72435886 72435886 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 21 10 16 0 ENST00000377197.3:c.91G>A p.Gly31Ser p.G31S ENST00000377197 NM_001010940.1 31 Ggc/Agc 0 +C9orf79 UCSF GRCh37 9 90500676 90500676 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 33 62 0 ENST00000325643.5:c.1274C>T p.Ala425Val p.A425V ENST00000325643 NM_178828.4 425 gCc/gTc 0 +CA13 UCSF GRCh37 8 86171690 86171690 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 6 76 0 ENST00000321764.3:c.276G>A p.Arg92= p.R92= ENST00000321764 NM_198584.2 92 cgG/cgA 0 +CABIN1 UCSF GRCh37 22 24468334 24468334 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 10 15 0 ENST00000263119.5:c.2506G>A p.Glu836Lys p.E836K ENST00000263119 NM_012295.3 836 Gag/Aag 0 +CABYR UCSF GRCh37 18 21739906 21739906 + 3_prime_UTR_variant,NMD_transcript_variant 3'UTR SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 72 135 0 ENST00000463087.1:c.*487G>A *163* ENST00000463087 0 +CACNA1B UCSF GRCh37 9 140811728 140811728 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 96 23 43 0 ENST00000371372.1:c.811G>A p.Glu271Lys p.E271K ENST00000371372 NM_001243812.1 271 Gag/Aag 0 +CACNA1H UCSF GRCh37 16 1262081 1262081 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 19 31 0 ENST00000348261.5:c.4702G>A p.Glu1568Lys p.E1568K ENST00000348261 NM_021098.2 1568 Gag/Aag 0 +CACNA2D1 UCSF GRCh37 7 81636994 81636994 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 5 30 0 ENST00000356253.5:c.1440+1G>A p.X480_splice ENST00000356253 0 +CACNA2D3 UCSF GRCh37 3 54871232 54871232 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 120 39 92 0 ENST00000288197.5:c.1445C>T p.Pro482Leu p.P482L ENST00000288197 482 cCt/cTt 0 +CACNA2D3 UCSF GRCh37 3 54786625 54786625 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 73 24 39 0 ENST00000288197.5:c.1168-1G>A p.X390_splice ENST00000288197 0 +CACNA2D3 UCSF GRCh37 3 55108230 55108230 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 29 58 0 ENST00000288197.5:c.3273G>A p.Arg1091= p.R1091= ENST00000288197 1091 agG/agA 0 +CACNB4 UCSF GRCh37 2 152830192 152830192 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 66 18 66 0 ENST00000539935.1:c.148-90308C>T *50* ENST00000539935 NM_001145798.1 0 +CAD UCSF GRCh37 2 27454858 27454858 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 21 49 0 ENST00000264705.4:c.2411C>T p.Thr804Ile p.T804I ENST00000264705 NM_004341.3 804 aCt/aTt 0 +CALML4 UCSF GRCh37 15 68497602 68497602 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 4 36 0 ENST00000467889.1:c.113G>A p.Ser38Asn p.S38N ENST00000467889 NM_033429.2 38 aGc/aAc 0 +CAMK2D UCSF GRCh37 4 114458538 114458538 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 29 87 0 ENST00000342666.5:c.476G>A p.Gly159Asp p.G159D ENST00000342666 159 gGc/gAc 0 +CAMSAP3 UCSF GRCh37 19 7673051 7673051 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 4 10 0 ENST00000160298.4:c.661C>T p.Pro221Ser p.P221S ENST00000160298 NM_020902.1 221 Ccc/Tcc 0 +CAPN9 UCSF GRCh37 1 230883271 230883271 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 23 25 0 ENST00000271971.2:c.29C>T p.Pro10Leu p.P10L ENST00000271971 NM_006615.2 10 cCt/cTt 0 +CAPS2 UCSF GRCh37 12 75715268 75715268 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 44 133 0 ENST00000409445.3:c.437G>A p.Gly146Asp p.G146D ENST00000409445 NM_032606.3 146 gGc/gAc 0 +CARM1 UCSF GRCh37 19 11018797 11018797 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 5 26 0 ENST00000327064.4:c.429G>A p.Glu143= p.E143= ENST00000327064 NM_199141.1 143 gaG/gaA 0 +CASC1 UCSF GRCh37 12 25308335 25308335 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 18 49 0 ENST00000320267.9:c.192G>A p.Arg64= p.R64= ENST00000320267 NM_001082973.1 64 agG/agA 0 +CASKIN2 UCSF GRCh37 17 73499335 73499335 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 8 16 0 ENST00000321617.3:c.1820G>A p.Gly607Glu p.G607E ENST00000321617 NM_020753.4 607 gGg/gAg 0 +CASP7 UCSF GRCh37 10 115489265 115489265 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 18 34 0 ENST00000345633.4:c.878C>T p.Ser293Phe p.S293F ENST00000345633 NM_033339.4 293 tCc/tTc 0 +CASP8 UCSF GRCh37 2 202134309 202134309 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 35 0 ENST00000432109.2:c.306-1930G>A *102* ENST00000432109 NM_033355.3 0 +CASP8AP2 UCSF GRCh37 6 90573777 90573777 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 63 182 0 ENST00000551025.1:n.3786C>T *1262* ENST00000551025 0 +CASP8AP2 UCSF GRCh37 6 90575760 90575760 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 4 32 65 0 ENST00000551025.1:n.4188C>T *1396* ENST00000551025 0 +CASZ1 UCSF GRCh37 1 10713516 10713516 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 6 12 0 ENST00000377022.3:c.2598C>T p.Ile866= p.I866= ENST00000377022 NM_001079843.2 866 atC/atT 0 +CATSPER2 UCSF GRCh37 15 43931847 43931847 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 11 105 0 ENST00000321596.5:c.711C>T p.Ala237= p.A237= ENST00000321596 237 gcC/gcT 0 +CBL UCSF GRCh37 11 119167732 119167732 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 30 42 0 ENST00000264033.4:c.2141C>T p.Ser714Phe p.S714F ENST00000264033 NM_005188.3 714 tCc/tTc 0 +CBLL1 UCSF GRCh37 7 107389382 107389382 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 131 23 91 0 ENST00000440859.3:c.71G>A p.Arg24Lys p.R24K ENST00000440859 NM_024814.2 24 aGa/aAa 0 +CBS UCSF GRCh37 21 44483181 44483181 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 14 17 0 ENST00000352178.5:c.836G>A p.Gly279Glu p.G279E ENST00000352178 NM_001178008.1 279 gGg/gAg 0 +CBX1 UCSF GRCh37 17 46154300 46154300 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 48 79 0 ENST00000225603.4:c.67G>A p.Val23Met p.V23M ENST00000225603 NM_001127228.1 23 Gtg/Atg 0 +CBX1 UCSF GRCh37 17 46153494 46153494 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 25 39 0 ENST00000225603.4:c.187C>T p.Leu63Phe p.L63F ENST00000225603 NM_001127228.1 63 Ctc/Ttc 0 +CC2D1A UCSF GRCh37 19 14038004 14038004 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 8 21 0 ENST00000318003.7:c.2242G>A p.Asp748Asn p.D748N ENST00000318003 NM_017721.4 748 Gac/Aac 0 +CC2D1A UCSF GRCh37 19 14037861 14037861 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 12 24 0 ENST00000318003.7:c.2196G>A p.Lys732= p.K732= ENST00000318003 NM_017721.4 732 aaG/aaA 0 +CC2D2A UCSF GRCh37 4 15565134 15565134 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 7 41 0 ENST00000424120.1:c.3171G>A p.Lys1057= p.K1057= ENST00000424120 1057 aaG/aaA 0 +CCDC108 UCSF GRCh37 2 219896288 219896288 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 25 54 0 ENST00000341552.5:c.738C>T p.Cys246= p.C246= ENST00000341552 NM_194302.3 246 tgC/tgT 0 +CCDC116 UCSF GRCh37 22 21990936 21990936 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 24 31 0 ENST00000292779.3:c.1419G>A p.Arg473= p.R473= ENST00000292779 NM_152612.2 473 agG/agA 0 +CCDC135 UCSF GRCh37 16 57734080 57734080 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 41 56 0 ENST00000360716.3:c.402G>A p.Arg134= p.R134= ENST00000360716 134 cgG/cgA 0 +CCDC165 UCSF GRCh37 18 8825043 8825043 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 5 11 0 ENST00000306329.11:c.4492C>T p.Leu1498= p.L1498= ENST00000306329 1498 Ctg/Ttg 0 +CCDC17 UCSF GRCh37 1 46087995 46087995 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 5 32 0 ENST00000528266.1:c.885G>A p.Glu295= p.E295= ENST00000528266 295 gaG/gaA 0 +CCDC82 UCSF GRCh37 11 96117446 96117446 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 150 30 134 0 ENST00000278520.5:c.466G>A p.Glu156Lys p.E156K ENST00000278520 156 Gag/Aag 0 +CCDC93 UCSF GRCh37 2 118766140 118766140 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 47 147 0 ENST00000376300.2:c.137G>A p.Gly46Asp p.G46D ENST00000376300 NM_019044.4 46 gGc/gAc 0 +CCHCR1 UCSF GRCh37 6 31118537 31118537 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 127 50 74 0 ENST00000376266.5:c.799G>A p.Glu267Lys p.E267K ENST00000376266 NM_019052.3 267 Gaa/Aaa 0 +CCNA1 UCSF GRCh37 13 37014243 37014243 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 25 124 0 ENST00000255465.4:c.1021G>A p.Val341Ile p.V341I ENST00000255465 341 Gta/Ata 0 +CCNH UCSF GRCh37 5 86700720 86700720 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 34 95 0 ENST00000256897.4:c.630C>T p.Ser210= p.S210= ENST00000256897 NM_001239.3 210 tcC/tcT 0 +CCP110 UCSF GRCh37 16 19548215 19548215 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 40 128 0 ENST00000381396.5:c.1224G>A p.Met408Ile p.M408I ENST00000381396 NM_001199022.1 408 atG/atA 0 +CD163 UCSF GRCh37 12 7637880 7637880 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 14 77 0 ENST00000359156.4:c.2591G>A p.Cys864Tyr p.C864Y ENST00000359156 NM_004244.5 864 tGc/tAc 0 +CD180 UCSF GRCh37 5 66478865 66478865 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 11 90 0 ENST00000256447.4:c.1806G>A p.Ser602= p.S602= ENST00000256447 NM_005582.2 602 tcG/tcA 0 +CD1D UCSF GRCh37 1 158151967 158151967 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 152 19 164 0 ENST00000368171.3:c.474G>A p.Trp158Ter p.W158* ENST00000368171 NM_001766.3 158 tgG/tgA 0 +CD209 UCSF GRCh37 19 7810855 7810855 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 91 58 74 0 ENST00000315599.7:c.297G>A p.Glu99= p.E99= ENST00000315599 NM_021155.3 99 gaG/gaA 0 +CD82 UCSF GRCh37 11 44640606 44640606 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 14 15 0 ENST00000227155.4:c.734G>A p.Gly245Glu p.G245E ENST00000227155 NM_002231.3 245 gGg/gAg 0 +CDAN1 UCSF GRCh37 15 43020446 43020446 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 15 24 0 ENST00000356231.3:c.2824C>T p.Pro942Ser p.P942S ENST00000356231 NM_138477.2 942 Cct/Tct 0 +CDCP2 UCSF GRCh37 1 54605765 54605765 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 8 14 0 ENST00000371330.1:c.778G>A p.Val260Ile p.V260I ENST00000371330 NM_201546.3 260 Gta/Ata 0 +CDH10 UCSF GRCh37 5 24537507 24537507 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 134 21 165 0 ENST00000264463.4:c.508C>T p.Pro170Ser p.P170S ENST00000264463 NM_006727.3 170 Ccc/Tcc 0 +CDH16 UCSF GRCh37 16 66944378 66944378 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 4 31 0 ENST00000299752.4:c.1952C>T p.Pro651Leu p.P651L ENST00000299752 NM_001204744.1 651 cCc/cTc 0 +CDH7 UCSF GRCh37 18 63511133 63511133 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 20 110 0 ENST00000323011.3:c.1067G>A p.Gly356Asp p.G356D ENST00000323011 NM_033646.1 356 gGt/gAt 0 +CDK11B UCSF GRCh37 1 1572140 1572140 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 28 43 0 ENST00000407249.3:c.1830C>T p.Asp610= p.D610= ENST00000407249 610 gaC/gaT 0 +CDK13 UCSF GRCh37 7 40134284 40134284 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 48 87 0 ENST00000181839.4:c.4244G>A p.Gly1415Asp p.G1415D ENST00000181839 NM_031267.3 1415 gGt/gAt 0 +CDK13 UCSF GRCh37 7 40134455 40134455 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 25 63 0 ENST00000181839.4:c.4415G>A p.Gly1472Asp p.G1472D ENST00000181839 NM_031267.3 1472 gGc/gAc 0 +CDKL3 UCSF GRCh37 5 133702168 133702168 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 17 76 0 ENST00000265334.4:c.47G>A p.Gly16Glu p.G16E ENST00000265334 NM_001113575.1 16 gGa/gAa 0 +CDKL5 UCSF GRCh37 X 18606251 18606251 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 6 54 66 0 ENST00000379989.3:c.732C>T p.Phe244= p.F244= ENST00000379989 NM_001037343.1 244 ttC/ttT 0 +CDR2L UCSF GRCh37 17 72997562 72997562 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 3 13 0 ENST00000337231.5:c.319G>A p.Ala107Thr p.A107T ENST00000337231 NM_014603.2 107 Gct/Act 0 +CECR2 UCSF GRCh37 22 17978518 17978518 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 10 96 0 ENST00000342247.5:c.356G>A p.Gly119Glu p.G119E ENST00000342247 119 gGa/gAa 0 +CELF2 UCSF GRCh37 10 11312703 11312703 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 18 27 0 ENST00000416382.2:c.672G>A p.Gln224= p.Q224= ENST00000416382 224 caG/caA 0 +CELF4 UCSF GRCh37 18 34850818 34850818 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.0041 P01_Rec Untested WXS Illumina HiSeq 15 14 17 0 ENST00000420428.2:c.1012G>A p.Val338Met p.V338M ENST00000420428 NM_020180.3 338 Gtg/Atg 0 +CELF4 UCSF GRCh37 18 34854413 34854413 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 8 24 0 ENST00000420428.2:c.662C>T p.Ala221Val p.A221V ENST00000420428 NM_020180.3 221 gCc/gTc 0 +CELSR1 UCSF GRCh37 22 46807624 46807624 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 11 42 0 ENST00000262738.3:c.4644G>A p.Gly1548= p.G1548= ENST00000262738 NM_014246.1 1548 ggG/ggA 0 +CELSR1 UCSF GRCh37 22 46931463 46931463 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 22 32 0 ENST00000262738.3:c.1605G>A p.Lys535= p.K535= ENST00000262738 NM_014246.1 535 aaG/aaA 0 +CELSR2 UCSF GRCh37 1 109795561 109795561 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 30 41 0 ENST00000271332.3:c.2860G>A p.Ala954Thr p.A954T ENST00000271332 NM_001408.2 954 Gcc/Acc 0 +CELSR2 UCSF GRCh37 1 109805763 109805763 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 16 20 0 ENST00000271332.3:c.4709-1G>A p.X1570_splice ENST00000271332 NM_001408.2 0 +CELSR2 UCSF GRCh37 1 109807557 109807557 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 25 51 0 ENST00000271332.3:c.5532C>T p.Thr1844= p.T1844= ENST00000271332 NM_001408.2 1844 acC/acT 0 +CENPC1 UCSF GRCh37 4 68378153 68378153 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 92 21 158 0 ENST00000273853.6:c.1579C>T p.Pro527Ser p.P527S ENST00000273853 NM_001812.2 527 Cca/Tca 0 +CENPJ UCSF GRCh37 13 25457353 25457353 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 76 36 131 0 ENST00000381884.4:c.3979G>A p.Asp1327Asn p.D1327N ENST00000381884 NM_018451.4 1327 Gac/Aac 0 +CEP104 UCSF GRCh37 1 3740108 3740108 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 31 69 0 ENST00000378230.3:c.2383C>T p.Leu795= p.L795= ENST00000378230 NM_014704.3 795 Ctg/Ttg 0 +CEP112 UCSF GRCh37 17 63898345 63898345 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 23 79 0 ENST00000392769.2:c.2088C>T p.Asn696= p.N696= ENST00000392769 NM_145036.3 696 aaC/aaT 0 +CEP95 UCSF GRCh37 17 62504709 62504709 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 153 24 145 0 ENST00000556440.2:c.20-1G>A p.X7_splice ENST00000556440 NM_138363.1 0 +CES2 UCSF GRCh37 16 66975428 66975428 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 7 32 0 ENST00000317091.4:c.1127G>A p.Gly376Glu p.G376E ENST00000317091 NM_003869.5 376 gGa/gAa 0 +CES3 UCSF GRCh37 16 66997748 66997748 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 4 14 0 ENST00000303334.4:c.470C>T p.Ala157Val p.A157V ENST00000303334 NM_024922.5 157 gCc/gTc 0 +CES3 UCSF GRCh37 16 66997711 66997711 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 11 24 0 ENST00000303334.4:c.433G>A p.Val145Ile p.V145I ENST00000303334 NM_024922.5 145 Gta/Ata 0 +CES3 UCSF GRCh37 16 67006758 67006758 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 24 56 0 ENST00000303334.4:c.1522G>A p.Asp508Asn p.D508N ENST00000303334 NM_024922.5 508 Gac/Aac 0 +CETN1 UCSF GRCh37 18 580808 580808 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 11 30 0 ENST00000327228.3:c.400G>A p.Gly134Arg p.G134R ENST00000327228 NM_004066.1 134 Ggg/Agg 0 +CFDP1 UCSF GRCh37 16 75338931 75338931 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 46 144 0 ENST00000283882.3:c.800G>A p.Gly267Glu p.G267E ENST00000283882 NM_006324.2 267 gGg/gAg 0 +CFH UCSF GRCh37 1 196695721 196695721 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 26 106 0 ENST00000367429.4:c.1995G>A p.Met665Ile p.M665I ENST00000367429 NM_000186.3 665 atG/atA 0 +CHAD UCSF GRCh37 17 48545744 48545744 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 3 20 0 ENST00000258969.4:c.431C>T p.Ser144Phe p.S144F ENST00000258969 144 tCc/tTc 0 +CHD3 UCSF GRCh37 17 7798765 7798765 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P01_Rec Untested WXS Illumina HiSeq 17 0 ENST00000330494.7:c.1618delC p.Arg540ValfsTer16 p.R540Vfs*16 ENST00000330494 NM_001005273.2 538 Ccc/cc 0 +CHI3L1 UCSF GRCh37 1 203154428 203154428 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 8 32 0 ENST00000255409.3:c.141C>T p.Asp47= p.D47= ENST00000255409 NM_001276.2 47 gaC/gaT 0 +CHIA UCSF GRCh37 1 111863037 111863037 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 5 42 0 ENST00000343320.6:c.1380C>T p.Cys460= p.C460= ENST00000343320 460 tgC/tgT 0 +CHST4 UCSF GRCh37 16 71570829 71570829 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 17 41 0 ENST00000338482.5:c.249G>A p.Lys83= p.K83= ENST00000338482 83 aaG/aaA 0 +CHST5 UCSF GRCh37 16 75563991 75563991 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 9 19 0 ENST00000336257.3:c.292G>A p.Val98Met p.V98M ENST00000336257 NM_024533.4 98 Gtg/Atg 0 +CIITA UCSF GRCh37 16 11000510 11000510 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 7 10 0 ENST00000324288.8:c.1161G>A p.Trp387Ter p.W387* ENST00000324288 NM_000246.3 387 tgG/tgA 0 +CKAP5 UCSF GRCh37 11 46772992 46772992 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 51 84 0 ENST00000529230.1:c.5226C>T p.Val1742= p.V1742= ENST00000529230 1742 gtC/gtT 0 +CKM UCSF GRCh37 19 45821138 45821138 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 3 12 25 0 ENST00000221476.3:c.293G>A p.Gly98Glu p.G98E ENST00000221476 NM_001824.4 98 gGg/gAg 0 +CLASP1 UCSF GRCh37 2 122125250 122125250 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 60 32 63 0 ENST00000263710.4:c.3800A>G p.Tyr1267Cys p.Y1267C ENST00000263710 NM_015282.2 1267 tAc/tGc 0 +CLCN6 UCSF GRCh37 1 11888662 11888662 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 13 67 0 ENST00000346436.6:c.1102C>T p.Pro368Ser p.P368S ENST00000346436 NM_001286.3 368 Ccg/Tcg 0 +CLCN7 UCSF GRCh37 16 1511666 1511666 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 5 9 0 ENST00000382745.4:c.223C>T p.Pro75Ser p.P75S ENST00000382745 NM_001287.5 75 Cct/Tct 0 +CLCNKB UCSF GRCh37 1 16377381 16377381 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 7 9 16 0 ENST00000375679.4:c.1065G>A p.Lys355= p.K355= ENST00000375679 NM_000085.4 355 aaG/aaA 0 +CLDN12 UCSF GRCh37 7 90042263 90042263 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 95 29 65 0 ENST00000287916.4:c.273C>T p.Pro91= p.P91= ENST00000287916 NM_001185073.2 91 ccC/ccT 0 +CLEC16A UCSF GRCh37 16 11272435 11272435 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 8 20 0 ENST00000409790.1:c.3050G>A p.Ser1017Asn p.S1017N ENST00000409790 NM_015226.2 1017 aGc/aAc 0 +CLEC4M UCSF GRCh37 19 7831562 7831562 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 18 29 0 ENST00000327325.5:c.805C>T p.Pro269Ser p.P269S ENST00000327325 NM_001144909.1 269 Ccc/Tcc 0 +CLMN UCSF GRCh37 14 95669764 95669764 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 25 53 0 ENST00000298912.4:c.1922G>A p.Gly641Asp p.G641D ENST00000298912 NM_024734.3 641 gGc/gAc 0 +CLN6 UCSF GRCh37 15 68500543 68500543 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 14 26 0 ENST00000249806.5:c.871C>T p.Pro291Ser p.P291S ENST00000249806 NM_017882.2 291 Ccg/Tcg 0 +CLN8 UCSF GRCh37 8 1719420 1719420 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 4 32 0 ENST00000331222.4:c.200C>T p.Ala67Val p.A67V ENST00000331222 NM_018941.3 67 gCg/gTg 0 +CLNK UCSF GRCh37 4 10566344 10566344 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 62 100 0 ENST00000226951.6:c.350C>T p.Ser117Phe p.S117F ENST00000226951 NM_052964.2 117 tCt/tTt 0 +CLTCL1 UCSF GRCh37 22 19187248 19187248 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 11 49 0 ENST00000427926.1:c.3870C>T p.Tyr1290= p.Y1290= ENST00000427926 1290 taC/taT 0 +CMYA5 UCSF GRCh37 5 79034707 79034707 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 105 35 98 0 ENST00000446378.2:c.10119C>T p.Val3373= p.V3373= ENST00000446378 NM_153610.3 3373 gtC/gtT 0 +CNGA3 UCSF GRCh37 2 99008330 99008330 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 8 24 0 ENST00000272602.2:c.570C>T p.Ala190= p.A190= ENST00000272602 190 gcC/gcT 0 +CNTD1 UCSF GRCh37 17 40961508 40961508 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 26 43 0 ENST00000588408.1:c.948C>T p.His316= p.H316= ENST00000588408 NM_173478.2 316 caC/caT 0 +CNTNAP2 UCSF GRCh37 7 148106483 148106483 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 27 51 0 ENST00000361727.3:c.3716C>T p.Ala1239Val p.A1239V ENST00000361727 NM_014141.5 1239 gCc/gTc 0 +CNTNAP5 UCSF GRCh37 2 125367388 125367388 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 95 17 69 0 ENST00000431078.1:c.1764G>A p.Glu588= p.E588= ENST00000431078 NM_130773.3 588 gaG/gaA 0 +COASY UCSF GRCh37 17 40715185 40715185 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 13 29 0 ENST00000393818.2:c.545G>A p.Gly182Glu p.G182E ENST00000393818 NM_025233.6 182 gGg/gAg 0 +COASY UCSF GRCh37 17 40717701 40717701 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 3 19 0 ENST00000393818.2:c.1510G>A p.Asp504Asn p.D504N ENST00000393818 NM_025233.6 504 Gat/Aat 0 +COG1 UCSF GRCh37 17 71193510 71193510 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 7 48 0 ENST00000299886.4:c.888G>A p.Glu296= p.E296= ENST00000299886 NM_018714.2 296 gaG/gaA 0 +COG5 UCSF GRCh37 7 107167779 107167779 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 10 25 0 ENST00000347053.3:c.534G>A p.Arg178= p.R178= ENST00000347053 NM_181733.2 178 agG/agA 0 +COL10A1 UCSF GRCh37 6 116442681 116442681 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 12 62 0 ENST00000243222.4:c.598G>A p.Gly200Ser p.G200S ENST00000243222 NM_000493.3 200 Ggt/Agt 0 +COL11A1 UCSF GRCh37 1 103412473 103412473 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 14 4 18 0 ENST00000370096.3:c.3208C>T p.Pro1070Ser p.P1070S ENST00000370096 NM_001854.3 1070 Cca/Tca 0 +COL11A1 UCSF GRCh37 1 103354311 103354311 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 38 78 0 ENST00000370096.3:c.4522C>T p.Pro1508Ser p.P1508S ENST00000370096 NM_001854.3 1508 Cct/Tct 0 +COL17A1 UCSF GRCh37 10 105795079 105795079 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 3 8 0 ENST00000353479.5:c.3561G>A p.Gly1187= p.G1187= ENST00000353479 NM_000494.3 1187 ggG/ggA 0 +COL19A1 UCSF GRCh37 6 70639353 70639353 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 7 18 64 0 ENST00000322773.4:c.427G>A p.Glu143Lys p.E143K ENST00000322773 NM_001858.4 143 Gaa/Aaa 0 +COL25A1 UCSF GRCh37 4 109753579 109753579 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 10 54 0 ENST00000399132.1:c.1667G>A p.Gly556Asp p.G556D ENST00000399132 NM_198721.2 556 gGt/gAt 0 +COL27A1 UCSF GRCh37 9 116931127 116931127 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 120 38 99 0 ENST00000356083.3:c.1292G>A p.Gly431Glu p.G431E ENST00000356083 NM_032888.2 431 gGa/gAa 0 +COL27A1 UCSF GRCh37 9 117029826 117029826 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 7 14 0 ENST00000356083.3:c.3490G>A p.Ala1164Thr p.A1164T ENST00000356083 NM_032888.2 1164 Gcc/Acc 0 +COL4A1 UCSF GRCh37 13 110826345 110826345 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 15 30 0 ENST00000375820.4:c.3407G>A p.Gly1136Asp p.G1136D ENST00000375820 NM_001845.4 1136 gGt/gAt 0 +COL4A3 UCSF GRCh37 2 228134689 228134689 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 15 70 0 ENST00000396578.3:c.1568G>A p.Gly523Glu p.G523E ENST00000396578 NM_000091.4 523 gGa/gAa 0 +COL4A4 UCSF GRCh37 2 227979410 227979410 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 19 83 0 ENST00000396625.3:c.492C>T p.Gly164= p.G164= ENST00000396625 NM_000092.4 164 ggC/ggT 0 +COL4A6 UCSF GRCh37 X 107408677 107408677 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 14 23 0 ENST00000372216.4:c.3734C>T p.Ala1245Val p.A1245V ENST00000372216 NM_001847.2 1245 gCc/gTc 0 +COL5A1 UCSF GRCh37 9 137642402 137642402 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 8 25 0 ENST00000371817.3:c.1509C>T p.Arg503= p.R503= ENST00000371817 NM_001278074.1 503 cgC/cgT 0 +COL6A3 UCSF GRCh37 2 238253370 238253370 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 28 38 0 ENST00000295550.4:c.7291G>A p.Asp2431Asn p.D2431N ENST00000295550 NM_004369.3 2431 Gac/Aac 0 +COL6A3 UCSF GRCh37 2 238287287 238287287 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 11 52 0 ENST00000295550.4:c.2489C>T p.Ala830Val p.A830V ENST00000295550 NM_004369.3 830 gCt/gTt 0 +COPS2 UCSF GRCh37 15 49437259 49437259 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 40 44 93 0 ENST00000388901.5:c.71G>A p.Ser24Asn p.S24N ENST00000388901 NM_001143887.1 24 aGt/aAt 0 +CORIN UCSF GRCh37 4 47605463 47605463 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 6 26 0 ENST00000273857.4:c.2763G>A p.Glu921= p.E921= ENST00000273857 NM_006587.3 921 gaG/gaA 0 +CPA2 UCSF GRCh37 7 129917712 129917712 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 5 19 0 ENST00000222481.4:c.743G>A p.Cys248Tyr p.C248Y ENST00000222481 NM_001869.2 248 tGt/tAt 0 +CPAMD8 UCSF GRCh37 19 17007002 17007002 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 3 9 0 ENST00000443236.1:c.5552G>A p.Gly1851Glu p.G1851E ENST00000443236 NM_015692.2 1851 gGg/gAg 0 +CPAMD8 UCSF GRCh37 19 17100452 17100452 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 7 23 0 ENST00000443236.1:c.1536+1G>A p.X512_splice ENST00000443236 NM_015692.2 0 +CPEB2 UCSF GRCh37 4 15009220 15009220 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 23 54 0 ENST00000507071.1:c.633+10G>A *211* ENST00000507071 0 +CPEB4 UCSF GRCh37 5 173378942 173378942 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 32 122 0 ENST00000265085.5:c.1780+1G>A p.X594_splice ENST00000265085 NM_030627.2 0 +CPNE3 UCSF GRCh37 8 87558910 87558910 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 75 61 136 0 ENST00000198765.4:c.819+1G>A p.X273_splice ENST00000198765 0 +CPNE4 UCSF GRCh37 3 131624151 131624151 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 6 57 0 ENST00000429747.1:c.137C>T p.Pro46Leu p.P46L ENST00000429747 NM_130808.1 46 cCc/cTc 0 +CPSF3 UCSF GRCh37 2 9583672 9583672 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 179 20 171 0 ENST00000238112.3:c.1124C>T p.Thr375Ile p.T375I ENST00000238112 NM_016207.3 375 aCt/aTt 0 +CPSF6 UCSF GRCh37 12 69652471 69652471 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 39 51 0 ENST00000435070.2:c.796C>T p.Pro266Ser p.P266S ENST00000435070 NM_007007.2 266 Cct/Tct 0 +CPSF7 UCSF GRCh37 11 61183722 61183722 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 24 31 0 ENST00000394888.4:c.820C>T p.Pro274Ser p.P274S ENST00000394888 NM_001136040.2 274 Cct/Tct 0 +CPT1A UCSF GRCh37 11 68574938 68574938 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 6 19 0 ENST00000265641.5:c.450G>A p.Trp150Ter p.W150* ENST00000265641 NM_001876.3 150 tgG/tgA 0 +CPT1B UCSF GRCh37 22 51011961 51011961 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 4 29 0 ENST00000312108.7:c.1154C>T p.Thr385Ile p.T385I ENST00000312108 NM_152246.2 385 aCt/aTt 0 +CPT1B UCSF GRCh37 22 51012002 51012002 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 6 20 0 ENST00000312108.7:c.1113C>T p.Pro371= p.P371= ENST00000312108 NM_152246.2 371 ccC/ccT 0 +CPT1B UCSF GRCh37 22 51010435 51010435 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 13 27 0 ENST00000312108.7:c.1575G>A p.Gln525= p.Q525= ENST00000312108 NM_152246.2 525 caG/caA 0 +CR1 UCSF GRCh37 1 207741179 207741179 + synonymous_variant Silent SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 95 11 114 0 ENST00000367051.1:c.2613T>C p.Cys871= p.C871= ENST00000367051 871 tgT/tgC 0 +CREB1 UCSF GRCh37 2 208439999 208439999 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 76 53 88 0 ENST00000432329.2:c.551C>T p.Ala184Val p.A184V ENST00000432329 NM_134442.3 184 gCc/gTc 0 +CREB3L2 UCSF GRCh37 7 137569748 137569748 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 16 53 0 ENST00000330387.6:c.1263C>T p.Ala421= p.A421= ENST00000330387 NM_194071.3 421 gcC/gcT 0 +CRIPAK UCSF GRCh37 4 1388759 1388759 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.037,snp132_rs112233131 P01_Rec Untested WXS Illumina HiSeq 65 10 26 1 ENST00000324803.4:c.460C>T p.Arg154Trp p.R154W ENST00000324803 NM_175918.3 154 Cgg/Tgg 0 +CRYZL1 UCSF GRCh37 21 34997057 34997057 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 36 96 0 ENST00000381554.3:c.76C>T p.Pro26Ser p.P26S ENST00000381554 NM_145858.2 26 Cct/Tct 0 +CSDE1 UCSF GRCh37 1 115261250 115261250 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 8 37 0 ENST00000358528.4:c.2333G>A p.Gly778Glu p.G778E ENST00000358528 NM_001007553.2 778 gGa/gAa 0 +CSRNP3 UCSF GRCh37 2 166514344 166514344 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 37 56 0 ENST00000314499.7:c.222C>T p.Tyr74= p.Y74= ENST00000314499 NM_001172173.1 74 taC/taT 0 +CST9 UCSF GRCh37 20 23586283 23586283 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 29 52 0 ENST00000376971.3:c.219C>T p.Val73= p.V73= ENST00000376971 NM_001008693.2 73 gtC/gtT 0 +CSTF2T UCSF GRCh37 10 53459172 53459172 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 42 92 0 ENST00000331173.4:c.138G>A p.Arg46= p.R46= ENST00000331173 NM_015235.2 46 cgG/cgA 0 +CTBP2 UCSF GRCh37 10 126683197 126683197 + missense_variant Missense_Mutation SNP T T C snp132_rs74341800 P01_Rec Untested WXS Illumina HiSeq 24 5 39 1 ENST00000337195.5:c.621A>G p.Ile207Met p.I207M ENST00000337195 NM_001329.2 207 atA/atG 0 +CTC1 UCSF GRCh37 17 8138176 8138176 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 10 28 0 ENST00000315684.8:c.1508G>A p.Gly503Glu p.G503E ENST00000315684 NM_025099.5 503 gGa/gAa 0 +CTIF UCSF GRCh37 18 46284567 46284567 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 31 41 0 ENST00000256413.3:c.862G>A p.Asp288Asn p.D288N ENST00000256413 NM_014772.2 288 Gac/Aac 0 +CTLA4 UCSF GRCh37 2 204732679 204732679 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 53 14 58 0 ENST00000302823.3:c.14G>A p.Gly5Glu p.G5E ENST00000302823 NM_005214.4 5 gGa/gAa 0 +CTNNAL1 UCSF GRCh37 9 111705105 111705105 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 91 46 75 0 ENST00000325551.4:c.2149G>A p.Glu717Lys p.E717K ENST00000325551 NM_003798.2 717 Gaa/Aaa 0 +CTNNAL1 UCSF GRCh37 9 111714757 111714757 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 8 59 0 ENST00000325551.4:c.1647G>A p.Leu549= p.L549= ENST00000325551 NM_003798.2 549 ctG/ctA 0 +CTNNB1 UCSF GRCh37 3 41279535 41279535 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 26 107 0 ENST00000349496.5:c.2105C>T p.Ala702Val p.A702V ENST00000349496 NM_001904.3 702 gCc/gTc 0 +CTNND1 UCSF GRCh37 11 57583390 57583390 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 10 21 0 ENST00000399050.4:c.2812G>A p.Asp938Asn p.D938N ENST00000399050 NM_001085458.1 938 Gac/Aac 0 +CTPS UCSF GRCh37 1 41450499 41450500 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 0 ENST00000372616.1:c.177dup p.Val60CysfsTer4 p.V60Cfs*4 ENST00000372616 58 gtt/gtTt 0 +CTR9 UCSF GRCh37 11 10785061 10785061 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 24 46 0 ENST00000361367.2:c.933G>A p.Gln311= p.Q311= ENST00000361367 NM_014633.3 311 caG/caA 0 +CTSL2 UCSF GRCh37 9 99797080 99797080 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 110 50 113 0 ENST00000259470.5:c.833G>A p.Gly278Asp p.G278D ENST00000259470 NM_001333.3 278 gGt/gAt 0 +CTTNBP2NL UCSF GRCh37 1 112999270 112999270 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 54 99 0 ENST00000271277.6:c.1156C>T p.Pro386Ser p.P386S ENST00000271277 NM_018704.2 386 Cca/Tca 0 +CUL4A UCSF GRCh37 13 113897333 113897333 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 48 71 0 ENST00000375440.4:c.1087C>T p.Gln363Ter p.Q363* ENST00000375440 NM_001008895.2 363 Caa/Taa 0 +CUL9 UCSF GRCh37 6 43156361 43156361 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 13 40 0 ENST00000252050.4:c.2088C>T p.Asn696= p.N696= ENST00000252050 NM_015089.2 696 aaC/aaT 0 +CXorf26 UCSF GRCh37 X 75395376 75395376 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 5 21 36 0 ENST00000373358.3:c.225C>T p.Phe75= p.F75= ENST00000373358 NM_016500.3 75 ttC/ttT 0 +CYB5RL UCSF GRCh37 1 54661173 54661173 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 3 9 0 ENST00000534324.1:c.117C>T p.Asp39= p.D39= ENST00000534324 39 gaC/gaT 0 +CYLD UCSF GRCh37 16 50810182 50810182 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 19 48 0 ENST00000311559.9:c.1015G>A p.Ala339Thr p.A339T ENST00000311559 NM_015247.2 339 Gct/Act 0 +CYP20A1 UCSF GRCh37 2 204137398 204137398 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 7 46 0 ENST00000356079.4:c.606G>A p.Trp202Ter p.W202* ENST00000356079 NM_177538.2 202 tgG/tgA 0 +CYP21A2 UCSF GRCh37 6 31974229 31974229 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 3 19 0 ENST00000342991.6:n.817G>A *273* ENST00000342991 0 +CYP26B1 UCSF GRCh37 2 72360198 72360198 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 6 19 0 ENST00000001146.2:c.1100C>T p.Pro367Leu p.P367L ENST00000001146 NM_019885.3 367 cCc/cTc 0 +CYP2A13 UCSF GRCh37 19 41594918 41594918 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 16 22 0 ENST00000330436.3:c.265G>A p.Glu89Lys p.E89K ENST00000330436 NM_000766.4 89 Gag/Aag 0 +CYP2C8 UCSF GRCh37 10 96802705 96802705 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 88 19 66 0 ENST00000371270.3:c.1091C>T p.Thr364Ile p.T364I ENST00000371270 NM_000770.3 364 aCc/aTc 0 +CYP2S1 UCSF GRCh37 19 41700576 41700576 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 10 33 0 ENST00000310054.4:c.305G>A p.Gly102Glu p.G102E ENST00000310054 NM_030622.6 102 gGa/gAa 0 +CYP3A43 UCSF GRCh37 7 99457614 99457614 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 17 82 0 ENST00000354829.2:c.1026+1G>A p.X342_splice ENST00000354829 NM_057095.2 0 +CYP4A11 UCSF GRCh37 1 47402439 47402439 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 5 27 0 ENST00000310638.4:c.407G>A p.Gly136Glu p.G136E ENST00000310638 NM_000778.3 136 gGg/gAg 0 +CYP4X1 UCSF GRCh37 1 47512236 47512236 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 12 47 0 ENST00000371901.3:c.1171C>T p.Pro391Ser p.P391S ENST00000371901 NM_178033.1 391 Cca/Tca 0 +DAGLB UCSF GRCh37 7 6472571 6472571 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 3 19 0 ENST00000297056.6:c.698G>A p.Ser233Asn p.S233N ENST00000297056 NM_139179.3 233 aGc/aAc 0 +DBH UCSF GRCh37 9 136509382 136509382 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 10 25 0 ENST00000393056.2:c.964C>T p.Pro322Ser p.P322S ENST00000393056 NM_000787.3 322 Cca/Tca 0 +DBH UCSF GRCh37 9 136522333 136522333 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 10 17 0 ENST00000393056.2:c.1704C>T p.Ser568= p.S568= ENST00000393056 NM_000787.3 568 tcC/tcT 0 +DCDC2B UCSF GRCh37 1 32674838 32674838 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 28 30 0 ENST00000409358.1:c.144G>A p.Gln48= p.Q48= ENST00000409358 NM_001099434.1 48 caG/caA 0 +DCDC5 UCSF GRCh37 11 30921143 30921143 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 133 19 142 0 ENST00000303697.4:c.772G>C p.Lys258Asn p.K258N ENST00000303697 258 aaG/aaC 0 +DCHS2 UCSF GRCh37 4 155237124 155237124 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 27 55 0 ENST00000357232.4:c.3671C>A p.Thr1224Asn p.T1224N ENST00000357232 NM_017639.3 1224 aCc/aAc 0 +DDB1 UCSF GRCh37 11 61076544 61076544 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 25 47 0 ENST00000301764.7:c.2572C>T p.Leu858= p.L858= ENST00000301764 NM_001923.4 858 Cta/Tta 0 +DDHD1 UCSF GRCh37 14 53570506 53570506 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 22 75 0 ENST00000323669.5:c.907G>A p.Glu303Lys p.E303K ENST00000323669 NM_001160148.1 303 Gaa/Aaa 0 +DDR1 UCSF GRCh37 6 30864491 30864491 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 23 43 25 0 ENST00000324771.8:c.1718A>G p.Asp573Gly p.D573G ENST00000324771 573 gAc/gGc 0 +DDX11 UCSF GRCh37 12 31256558 31256558 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 13 27 0 ENST00000545668.1:c.2579G>A p.Gly860Glu p.G860E ENST00000545668 NM_001257144.1 860 gGa/gAa 0 +DDX3X UCSF GRCh37 X 41203567 41203567 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 11 36 0 ENST00000399959.2:c.940G>A p.Glu314Lys p.E314K ENST00000399959 NM_001193417.1 314 Gaa/Aaa 0 +DDX50 UCSF GRCh37 10 70666491 70666491 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 16 68 0 ENST00000373585.3:c.112C>T p.His38Tyr p.H38Y ENST00000373585 NM_024045.1 38 Cat/Tat 0 +DDX56 UCSF GRCh37 7 44610391 44610391 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 36 45 0 ENST00000258772.5:c.976G>A p.Gly326Ser p.G326S ENST00000258772 NM_001257189.1 326 Ggc/Agc 0 +DENND2A UCSF GRCh37 7 140301329 140301329 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 34 71 0 ENST00000275884.6:c.869G>A p.Arg290Lys p.R290K ENST00000275884 290 aGg/aAg 0 +DENND2A UCSF GRCh37 7 140268573 140268573 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 23 36 0 ENST00000275884.6:c.1581G>A p.Glu527= p.E527= ENST00000275884 527 gaG/gaA 0 +DENND2C UCSF GRCh37 1 115161059 115161059 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 41 135 0 ENST00000393274.1:c.1272G>A p.Lys424= p.K424= ENST00000393274 NM_001256404.1 424 aaG/aaA 0 +DENND3 UCSF GRCh37 8 142176467 142176467 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 23 40 0 ENST00000262585.2:c.1492G>A p.Gly498Ser p.G498S ENST00000262585 NM_014957.2 498 Ggc/Agc 0 +DFNB31 UCSF GRCh37 9 117185744 117185744 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 13 20 0 ENST00000362057.3:c.1476C>T p.Asp492= p.D492= ENST00000362057 NM_001173425.1 492 gaC/gaT 0 +DGKH UCSF GRCh37 13 42799463 42799463 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 98 15 101 0 ENST00000337343.4:c.3574-3772G>A *1192* ENST00000337343 NM_178009.3 0 +DHCR24 UCSF GRCh37 1 55337053 55337053 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 10 19 0 ENST00000371269.3:c.846G>A p.Gly282= p.G282= ENST00000371269 NM_014762.3 282 ggG/ggA 0 +DIEXF UCSF GRCh37 1 210010322 210010322 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 33 77 0 ENST00000491415.2:c.828C>T p.Thr276= p.T276= ENST00000491415 NM_014388.6 276 acC/acT 0 +DIP2C UCSF GRCh37 10 410500 410500 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 3 20 0 ENST00000280886.6:c.2291G>A p.Gly764Glu p.G764E ENST00000280886 NM_014974.2 764 gGg/gAg 0 +DLAT UCSF GRCh37 11 111930758 111930758 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 43 162 0 ENST00000280346.6:c.1646G>A p.Arg549Lys p.R549K ENST00000280346 NM_001931.4 549 aGa/aAa 0 +DLC1 UCSF GRCh37 8 12957987 12957987 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 32 6 26 0 ENST00000276297.4:c.1859C>T p.Ser620Phe p.S620F ENST00000276297 NM_182643.2 620 tCc/tTc 0 +DLC1 UCSF GRCh37 8 12950182 12950182 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 20 13 37 0 ENST00000276297.4:c.3679G>A p.Val1227Met p.V1227M ENST00000276297 NM_182643.2 1227 Gtg/Atg 0 +DLG3 UCSF GRCh37 X 69720346 69720346 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 4 14 0 ENST00000374360.3:c.2171C>T p.Ser724Phe p.S724F ENST00000374360 NM_021120.3 724 tCc/tTc 0 +DLG4 UCSF GRCh37 17 7100192 7100192 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 15 0 ENST00000399506.2:c.967C>T p.Leu323= p.L323= ENST00000399506 323 Ctg/Ttg 0 +DLGAP1 UCSF GRCh37 18 3534464 3534464 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 6 39 0 ENST00000315677.3:c.2207C>T p.Thr736Ile p.T736I ENST00000315677 NM_004746.3 736 aCc/aTc 0 +DMD UCSF GRCh37 X 31697623 31697623 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 5 45 0 ENST00000357033.4:c.7741G>A p.Asp2581Asn p.D2581N ENST00000357033 NM_004007.2 2581 Gat/Aat 0 +DMD UCSF GRCh37 X 31893450 31893450 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 3 32 0 ENST00000357033.4:c.6953C>T p.Ala2318Val p.A2318V ENST00000357033 NM_004007.2 2318 gCt/gTt 0 +DMD UCSF GRCh37 X 32407765 32407765 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 33 59 0 ENST00000357033.4:c.4371G>A p.Lys1457= p.K1457= ENST00000357033 NM_004007.2 1457 aaG/aaA 0 +DMGDH UCSF GRCh37 5 78347287 78347287 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 27 61 0 ENST00000255189.3:c.568G>A p.Asp190Asn p.D190N ENST00000255189 NM_013391.3 190 Gat/Aat 0 +DMGDH UCSF GRCh37 5 78325822 78325822 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 18 57 0 ENST00000255189.3:c.1719C>T p.Pro573= p.P573= ENST00000255189 NM_013391.3 573 ccC/ccT 0 +DMRTC2 UCSF GRCh37 19 42355670 42355670 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 11 45 0 ENST00000269945.3:c.1010G>A p.Gly337Glu p.G337E ENST00000269945 NM_001040283.1 337 gGa/gAa 0 +DMXL1 UCSF GRCh37 5 118484522 118484522 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 18 104 0 ENST00000311085.8:c.3000G>A p.Trp1000Ter p.W1000* ENST00000311085 NM_005509.4 1000 tgG/tgA 0 +DNA2 UCSF GRCh37 10 70204774 70204774 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 25 127 0 ENST00000358410.3:c.1124G>A p.Arg375Lys p.R375K ENST00000358410 NM_001080449.2 375 aGa/aAa 0 +DNAH1 UCSF GRCh37 3 52400863 52400863 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 7 31 0 ENST00000420323.2:c.5725G>A p.Gly1909Ser p.G1909S ENST00000420323 NM_015512.4 1909 Ggc/Agc 0 +DNAH11 UCSF GRCh37 7 21609755 21609755 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 136 32 105 0 ENST00000409508.3:c.1263G>A p.Gln421= p.Q421= ENST00000409508 NM_001277115.1 421 caG/caA 0 +DNAH12 UCSF GRCh37 3 57458321 57458321 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 39 93 0 ENST00000351747.2:c.1728C>T p.Val576= p.V576= ENST00000351747 NM_178504.4 576 gtC/gtT 0 +DNAH17 UCSF GRCh37 17 76421618 76421618 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 5 24 0 ENST00000389840.5:c.13019C>T p.Pro4340Leu p.P4340L ENST00000389840 4340 cCc/cTc 0 +DNAH3 UCSF GRCh37 16 21132064 21132064 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 8 73 0 ENST00000261383.3:c.1696G>A p.Ala566Thr p.A566T ENST00000261383 NM_017539.1 566 Gca/Aca 0 +DNAH5 UCSF GRCh37 5 13792290 13792290 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 10 89 0 ENST00000265104.4:c.8261G>A p.Gly2754Asp p.G2754D ENST00000265104 NM_001369.2 2754 gGt/gAt 0 +DNAH8 UCSF GRCh37 6 38994438 38994438 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 19 38 0 ENST00000359357.3:c.13180C>T p.Pro4394Ser p.P4394S ENST00000359357 4394 Cct/Tct 0 +DNAH9 UCSF GRCh37 17 11550496 11550496 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 9 57 0 ENST00000262442.4:c.2078C>T p.Thr693Ile p.T693I ENST00000262442 NM_001372.3 693 aCt/aTt 0 +DNAI1 UCSF GRCh37 9 34512186 34512186 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 4 36 0 ENST00000242317.4:c.1391C>T p.Thr464Ile p.T464I ENST00000242317 NM_012144.3 464 aCt/aTt 0 +DNAJA2 UCSF GRCh37 16 47005263 47005263 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 21 72 0 ENST00000317089.5:c.360C>T p.Leu120= p.L120= ENST00000317089 NM_005880.3 120 ctC/ctT 0 +DNAJC10 UCSF GRCh37 2 183627480 183627480 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 39 86 0 ENST00000264065.7:c.2217G>A p.Gly739= p.G739= ENST00000264065 NM_018981.2 739 ggG/ggA 0 +DNAJC12 UCSF GRCh37 10 69565489 69565489 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 56 152 0 ENST00000225171.2:c.354G>A p.Lys118= p.K118= ENST00000225171 NM_021800.2 118 aaG/aaA 0 +DNAJC14 UCSF GRCh37 12 56216254 56216254 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 43 84 0 ENST00000317269.3:c.1801G>A p.Ala601Thr p.A601T ENST00000317269 NM_032364.5 601 Gct/Act 0 +DNAJC2 UCSF GRCh37 7 102982259 102982259 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 124 22 133 0 ENST00000379263.3:c.207G>A p.Gln69= p.Q69= ENST00000379263 NM_014377.1 69 caG/caA 0 +DNAJC4 UCSF GRCh37 11 64000195 64000195 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 19 35 0 ENST00000321685.3:c.385G>A p.Ala129Thr p.A129T ENST00000321685 NM_005528.3 129 Gca/Aca 0 +DNAJC6 UCSF GRCh37 1 65877089 65877089 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 22 62 0 ENST00000395325.3:c.2620C>T p.Leu874= p.L874= ENST00000395325 NM_014787.3 874 Ctg/Ttg 0 +DNHD1 UCSF GRCh37 11 6591862 6591862 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 4 23 0 ENST00000254579.6:c.13120G>A p.Asp4374Asn p.D4374N ENST00000254579 NM_144666.2 4374 Gat/Aat 0 +DNM1 UCSF GRCh37 9 130984532 130984532 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 13 30 0 ENST00000372923.3:c.906C>T p.Ser302= p.S302= ENST00000372923 NM_004408.2 302 agC/agT 0 +DNMT3B UCSF GRCh37 20 31386392 31386392 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 13 31 0 ENST00000328111.2:c.1617G>A p.Arg539= p.R539= ENST00000328111 NM_006892.3 539 cgG/cgA 0 +DOCK10 UCSF GRCh37 2 225639660 225639660 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 20 35 0 ENST00000258390.7:c.5975G>A p.Gly1992Glu p.G1992E ENST00000258390 NM_014689.2 1992 gGg/gAg 0 +DOCK3 UCSF GRCh37 3 51315054 51315054 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 7 17 30 0 ENST00000266037.9:c.2692G>A p.Glu898Lys p.E898K ENST00000266037 NM_004947.4 898 Gag/Aag 0 +DOCK4 UCSF GRCh37 7 111584879 111584879 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 56 94 0 ENST00000437633.1:c.831C>T p.His277= p.H277= ENST00000437633 NM_014705.3 277 caC/caT 0 +DOCK5 UCSF GRCh37 8 25257466 25257466 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 70 33 136 0 ENST00000276440.7:c.4744G>A p.Asp1582Asn p.D1582N ENST00000276440 NM_024940.6 1582 Gac/Aac 0 +DOCK9 UCSF GRCh37 13 99461624 99461624 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 7 65 0 ENST00000376460.1:c.5349G>A p.Arg1783= p.R1783= ENST00000376460 NM_015296.2 1783 cgG/cgA 0 +DOPEY2 UCSF GRCh37 21 37586854 37586854 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 66 50 116 0 ENST00000399151.3:c.1129G>A p.Gly377Arg p.G377R ENST00000399151 NM_005128.2 377 Ggg/Agg 0 +DPY19L4 UCSF GRCh37 8 95792605 95792605 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 28 90 0 ENST00000414645.2:c.1594G>A p.Ala532Thr p.A532T ENST00000414645 NM_181787.2 532 Gcc/Acc 0 +DPY19L4 UCSF GRCh37 8 95801990 95801990 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 53 148 0 ENST00000414645.2:c.2024G>A p.Gly675Asp p.G675D ENST00000414645 NM_181787.2 675 gGt/gAt 0 +DPY19L4 UCSF GRCh37 8 95800133 95800133 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 13 64 0 ENST00000414645.2:c.1860C>T p.Ile620= p.I620= ENST00000414645 NM_181787.2 620 atC/atT 0 +DR1 UCSF GRCh37 1 93819517 93819517 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 32 60 0 ENST00000370267.1:c.273G>A p.Leu91= p.L91= ENST00000370267 91 ttG/ttA 0 +DSCAML1 UCSF GRCh37 11 117352816 117352816 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 3 12 0 ENST00000321322.6:c.2601G>A p.Glu867= p.E867= ENST00000321322 NM_020693.2 867 gaG/gaA 0 +DSE UCSF GRCh37 6 116757372 116757372 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 6 39 0 ENST00000331677.3:c.1741G>A p.Glu581Lys p.E581K ENST00000331677 581 Gag/Aag 0 +DSG2 UCSF GRCh37 18 29116190 29116190 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 15 97 0 ENST00000261590.8:c.1449C>T p.Gly483= p.G483= ENST00000261590 NM_001943.3 483 ggC/ggT 0 +DSPP UCSF GRCh37 4 88533898 88533898 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 20 81 0 ENST00000282478.7:c.560C>T p.Ala187Val p.A187V ENST00000282478 187 gCt/gTt 0 +DST UCSF GRCh37 6 56382342 56382342 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 115 16 114 0 ENST00000244364.6:c.10337G>A p.Arg3446Lys p.R3446K ENST00000244364 NM_015548.4 3446 aGg/aAg 0 +DTNBP1 UCSF GRCh37 6 15523293 15523293 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 132 15 52 0 ENST00000344537.5:c.969G>A p.Glu323= p.E323= ENST00000344537 NM_001271667.1 323 gaG/gaA 0 +DUOX1 UCSF GRCh37 15 45431639 45431639 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 4 31 0 ENST00000321429.4:c.1231C>T p.Pro411Ser p.P411S ENST00000321429 NM_017434.3 411 Cca/Tca 0 +DUOX1 UCSF GRCh37 15 45454105 45454105 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 9 13 0 ENST00000321429.4:c.4026G>A p.Trp1342Ter p.W1342* ENST00000321429 NM_017434.3 1342 tgG/tgA 0 +DUOX1 UCSF GRCh37 15 45439634 45439634 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 6 8 12 0 ENST00000321429.4:c.2326C>T p.Leu776= p.L776= ENST00000321429 NM_017434.3 776 Ctg/Ttg 0 +DUOX2 UCSF GRCh37 15 45386390 45386390 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 27 11 41 0 ENST00000603300.1:c.4605G>A p.Arg1535= p.R1535= ENST00000603300 NM_014080.4 1535 agG/agA 0 +DUSP15 UCSF GRCh37 20 30452768 30452768 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 7 32 0 ENST00000278979.3:c.167C>T p.Pro56Leu p.P56L ENST00000278979 56 cCt/cTt 0 +DUSP16 UCSF GRCh37 12 12630433 12630433 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 33 45 0 ENST00000298573.4:c.*736G>A *246* ENST00000298573 0 +DYNC1I2 UCSF GRCh37 2 172604285 172604285 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 42 137 0 ENST00000397119.3:c.1804-1G>A p.X602_splice ENST00000397119 NM_001378.2 0 +DYNC2H1 UCSF GRCh37 11 103052580 103052580 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 32 0 ENST00000375735.2:c.6442T>C p.Tyr2148His p.Y2148H ENST00000375735 NM_001080463.1 2148 Tat/Cat 0 +DYRK1A UCSF GRCh37 21 38884787 38884787 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 29 104 0 ENST00000398960.2:c.2245C>T p.Pro749Ser p.P749S ENST00000398960 NM_001396.3 749 Ccc/Tcc 0 +DYRK1A UCSF GRCh37 21 38845044 38845044 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 37 87 0 ENST00000398960.2:c.69C>T p.Phe23= p.F23= ENST00000398960 NM_001396.3 23 ttC/ttT 0 +E2F3 UCSF GRCh37 6 20481556 20481556 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 193 26 134 0 ENST00000346618.3:c.625G>A p.Glu209Lys p.E209K ENST00000346618 NM_001949.4 209 Gaa/Aaa 0 +EBP UCSF GRCh37 X 48385564 48385564 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 9 29 0 ENST00000495186.1:c.360C>T p.Cys120= p.C120= ENST00000495186 NM_006579.2 120 tgC/tgT 0 +ECE1 UCSF GRCh37 1 21573749 21573749 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 8 28 0 ENST00000374893.6:c.1128G>A p.Glu376= p.E376= ENST00000374893 NM_001397.2 376 gaG/gaA 0 +EDIL3 UCSF GRCh37 5 83362330 83362330 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 11 82 0 ENST00000296591.5:c.747C>T p.Ala249= p.A249= ENST00000296591 NM_005711.4 249 gcC/gcT 0 +EFEMP2 UCSF GRCh37 11 65638811 65638811 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 15 32 0 ENST00000307998.6:c.184C>T p.Pro62Ser p.P62S ENST00000307998 NM_016938.4 62 Cct/Tct 0 +EHF UCSF GRCh37 11 34664174 34664174 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 5 26 0 ENST00000257831.3:c.-3-1G>A p.X1_splice ENST00000257831 NM_012153.5 0 +EIF2B5 UCSF GRCh37 3 183858423 183858423 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 6 52 0 ENST00000273783.3:c.1061G>A p.Ser354Asn p.S354N ENST00000273783 NM_003907.2 354 aGc/aAc 0 +EIF4ENIF1 UCSF GRCh37 22 31850321 31850321 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 11 34 0 ENST00000330125.5:c.1321G>A p.Gly441Ser p.G441S ENST00000330125 NM_019843.3 441 Ggt/Agt 0 +EIF4G1 UCSF GRCh37 3 184045073 184045073 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 4 13 19 0 ENST00000346169.2:c.3498G>A p.Arg1166= p.R1166= ENST00000346169 NM_198241.2 1166 cgG/cgA 0 +ELANE UCSF GRCh37 19 855960 855960 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 14 19 0 ENST00000263621.1:c.600G>A p.Gly200= p.G200= ENST00000263621 NM_001972.2 200 ggG/ggA 0 +ELL UCSF GRCh37 19 18572433 18572433 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 3 18 0 ENST00000262809.4:c.699C>T p.Gly233= p.G233= ENST00000262809 NM_006532.3 233 ggC/ggT 0 +ELN UCSF GRCh37 7 73450886 73450886 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 22 34 0 ENST00000358929.4:c.135G>A p.Gly45= p.G45= ENST00000358929 NM_001278939.1 45 ggG/ggA 0 +EML3 UCSF GRCh37 11 62378778 62378778 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 12 8 0 ENST00000394773.2:c.233C>T p.Pro78Leu p.P78L ENST00000394773 NM_153265.2 78 cCt/cTt 0 +EML5 UCSF GRCh37 14 89083072 89083072 + missense_variant,splice_region_variant Missense_Mutation SNP A A T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 14 73 0 ENST00000380664.5:c.5770T>A p.Phe1924Ile p.F1924I ENST00000380664 1924 Ttt/Att 0 +EMR2 UCSF GRCh37 19 14863278 14863278 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 19 25 0 ENST00000315576.3:c.1651C>T p.Leu551Phe p.L551F ENST00000315576 NM_013447.3 551 Ctc/Ttc 0 +EMR3 UCSF GRCh37 19 14748988 14748988 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 33 53 0 ENST00000253673.5:c.1413C>T p.Gly471= p.G471= ENST00000253673 NM_032571.3 471 ggC/ggT 0 +ENAM UCSF GRCh37 4 71507948 71507948 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 94 16 74 0 ENST00000396073.3:c.805C>T p.Pro269Ser p.P269S ENST00000396073 NM_031889.2 269 Ccc/Tcc 0 +ENGASE UCSF GRCh37 17 77075600 77075600 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 14 43 0 ENST00000579016.1:c.446C>T p.Pro149Leu p.P149L ENST00000579016 NM_001042573.2 149 cCc/cTc 0 +ENOX1 UCSF GRCh37 13 43987009 43987009 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 10 64 0 ENST00000261488.6:c.42C>T p.Pro14= p.P14= ENST00000261488 NM_017993.3 14 ccC/ccT 0 +ENPEP UCSF GRCh37 4 111470771 111470771 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 35 71 0 ENST00000265162.5:c.2313G>A p.Trp771Ter p.W771* ENST00000265162 NM_001977.3 771 tgG/tgA 0 +ENPP3 UCSF GRCh37 6 131973802 131973802 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 88 11 80 0 ENST00000357639.3:c.398G>A p.Cys133Tyr p.C133Y ENST00000357639 NM_005021.3 133 tGc/tAc 0 +ENTPD4 UCSF GRCh37 8 23297262 23297262 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 18 45 0 ENST00000358689.4:c.1049G>A p.Arg350Lys p.R350K ENST00000358689 NM_001128930.2 350 aGg/aAg 0 +EP300 UCSF GRCh37 22 41523561 41523561 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 32 82 0 ENST00000263253.7:c.977G>A p.Gly326Glu p.G326E ENST00000263253 NM_001429.3 326 gGa/gAa 0 +EPB41L4A UCSF GRCh37 5 111540139 111540139 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 39 86 0 ENST00000261486.5:c.1309C>T p.Pro437Ser p.P437S ENST00000261486 NM_022140.3 437 Cct/Tct 0 +EPCAM UCSF GRCh37 2 47601173 47601173 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 8 33 0 ENST00000263735.4:c.411G>A p.Glu137= p.E137= ENST00000263735 NM_002354.2 137 gaG/gaA 0 +EPG5 UCSF GRCh37 18 43496476 43496476 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 17 18 0 ENST00000282041.5:c.3311C>T p.Thr1104Ile p.T1104I ENST00000282041 NM_020964.2 1104 aCc/aTc 0 +EPHA10 UCSF GRCh37 1 38188718 38188718 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 3 27 0 ENST00000373048.4:c.1955G>A p.Gly652Glu p.G652E ENST00000373048 NM_001099439.1 652 gGa/gAa 0 +EPHA2 UCSF GRCh37 1 16475000 16475000 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 7 18 0 ENST00000358432.5:c.696C>T p.Asp232= p.D232= ENST00000358432 NM_004431.3 232 gaC/gaT 0 +EPHA7 UCSF GRCh37 6 93969092 93969092 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 50 43 69 0 ENST00000369303.4:c.1904T>C p.Ile635Thr p.I635T ENST00000369303 NM_004440.3 635 aTt/aCt 0 +EPHB3 UCSF GRCh37 3 184298559 184298559 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 4 27 33 0 ENST00000330394.2:c.2431G>A p.Ala811Thr p.A811T ENST00000330394 NM_004443.3 811 Gcc/Acc 0 +EPHB6 UCSF GRCh37 7 142563309 142563309 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 4 13 0 ENST00000392957.2:c.1026C>T p.Asn342= p.N342= ENST00000392957 NM_004445.4 342 aaC/aaT 0 +EPS8L3 UCSF GRCh37 1 110294697 110294697 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 15 79 0 ENST00000361965.4:c.1354G>A p.Ala452Thr p.A452T ENST00000361965 452 Gcc/Acc 0 +ERBB2 UCSF GRCh37 17 37883152 37883152 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 35 18 32 0 ENST00000269571.5:c.3055G>A p.Asp1019Asn p.D1019N ENST00000269571 1019 Gat/Aat 0 +ERBB2IP UCSF GRCh37 5 65371004 65371004 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 64 57 89 0 ENST00000284037.5:c.3909A>G p.Pro1303= p.P1303= ENST00000284037 NM_001253697.1 1303 ccA/ccG 0 +ERC2 UCSF GRCh37 3 55733445 55733445 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 162 19 95 0 ENST00000288221.6:c.2808G>A p.Gly936= p.G936= ENST00000288221 NM_015576.1 936 ggG/ggA 0 +ERCC6L UCSF GRCh37 X 71426212 71426212 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 44 38 0 ENST00000334463.3:c.2405G>A p.Gly802Asp p.G802D ENST00000334463 NM_017669.2 802 gGt/gAt 0 +ERCC6L UCSF GRCh37 X 71426791 71426791 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 14 45 0 ENST00000334463.3:c.1826C>T p.Thr609Ile p.T609I ENST00000334463 NM_017669.2 609 aCt/aTt 0 +ERI1 UCSF GRCh37 8 8887368 8887368 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 37 92 0 ENST00000250263.7:c.874C>T p.Pro292Ser p.P292S ENST00000250263 NM_153332.3 292 Cct/Tct 0 +ERI1 UCSF GRCh37 8 8887425 8887425 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 90 15 114 0 ENST00000250263.7:c.931C>T p.Gln311Ter p.Q311* ENST00000250263 NM_153332.3 311 Cag/Tag 0 +ESAM UCSF GRCh37 11 124623720 124623720 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 10 17 0 ENST00000278927.5:c.995C>T p.Thr332Ile p.T332I ENST00000278927 NM_138961.2 332 aCc/aTc 0 +ESCO2 UCSF GRCh37 8 27634036 27634036 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 13 81 0 ENST00000305188.8:c.211G>A p.Ala71Thr p.A71T ENST00000305188 NM_001017420.2 71 Gca/Aca 0 +ESRP1 UCSF GRCh37 8 95653643 95653643 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 17 113 0 ENST00000433389.2:c.97C>T p.Leu33= p.L33= ENST00000433389 NM_001034915.2 33 Ctg/Ttg 0 +ESRRA UCSF GRCh37 11 64083256 64083256 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 6 36 0 ENST00000000442.6:c.1090G>A p.Ala364Thr p.A364T ENST00000000442 364 Gcc/Acc 0 +ETS2 UCSF GRCh37 21 40194711 40194711 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 7 23 0 ENST00000360214.3:c.1308G>A p.Lys436= p.K436= ENST00000360214 NM_001256295.1 436 aaG/aaA 0 +EVPL UCSF GRCh37 17 74006448 74006448 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 9 20 0 ENST00000301607.3:c.2838G>A p.Arg946= p.R946= ENST00000301607 NM_001988.2 946 agG/agA 0 +EVPL UCSF GRCh37 17 74003406 74003406 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 15 29 0 ENST00000301607.3:c.5880C>T p.Leu1960= p.L1960= ENST00000301607 NM_001988.2 1960 ctC/ctT 0 +EXD2 UCSF GRCh37 14 69704412 69704412 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 3 11 0 ENST00000312994.5:c.1413C>T p.Asn471= p.N471= ENST00000312994 471 aaC/aaT 0 +EXOC1 UCSF GRCh37 4 56768539 56768539 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 63 8 53 0 ENST00000346134.7:c.2367G>A p.Val789= p.V789= ENST00000346134 NM_018261.3 789 gtG/gtA 0 +EXOC2 UCSF GRCh37 6 489001 489001 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 182 28 99 0 ENST00000230449.4:c.2659C>T p.Leu887Phe p.L887F ENST00000230449 NM_018303.5 887 Ctt/Ttt 0 +EXOSC1 UCSF GRCh37 10 99203044 99203044 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 106 19 106 0 ENST00000370902.3:c.172G>A p.Glu58Lys p.E58K ENST00000370902 NM_016046.3 58 Gaa/Aaa 0 +F5 UCSF GRCh37 1 169484688 169484688 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 98 76 128 0 ENST00000367797.3:c.6522G>A p.Val2174= p.V2174= ENST00000367797 NM_000130.4 2174 gtG/gtA 0 +F5 UCSF GRCh37 1 169510620 169510620 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 146 26 112 0 ENST00000367797.3:c.3708C>T p.Ser1236= p.S1236= ENST00000367797 NM_000130.4 1236 agC/agT 0 +F8 UCSF GRCh37 X 154157439 154157439 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 69 56 0 ENST00000360256.4:c.4626G>A p.Gly1542= p.G1542= ENST00000360256 NM_000132.3 1542 ggG/ggA 0 +FAAH2 UCSF GRCh37 X 57475016 57475016 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 12 42 0 ENST00000374900.4:c.1288G>A p.Ala430Thr p.A430T ENST00000374900 NM_174912.3 430 Gca/Aca 0 +FABP4 UCSF GRCh37 8 82391107 82391107 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 9 71 0 ENST00000256104.4:c.392G>A p.Arg131Lys p.R131K ENST00000256104 NM_001442.2 131 aGa/aAa 0 +FAM108C1 UCSF GRCh37 15 81046697 81046697 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 31 81 0 ENST00000258884.4:c.976C>T p.Leu326Phe p.L326F ENST00000258884 NM_021214.1 326 Ctt/Ttt 0 +FAM117B UCSF GRCh37 2 203589645 203589645 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 112 60 153 0 ENST00000392238.2:c.759G>A p.Glu253= p.E253= ENST00000392238 253 gaG/gaA 0 +FAM129A UCSF GRCh37 1 184765105 184765105 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 12 75 0 ENST00000367511.3:c.1793C>T p.Ala598Val p.A598V ENST00000367511 NM_052966.3 598 gCc/gTc 0 +FAM134C UCSF GRCh37 17 40761264 40761264 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 7 15 0 ENST00000309428.5:c.79G>A p.Gly27Ser p.G27S ENST00000309428 NM_178126.3 27 Ggc/Agc 0 +FAM135A UCSF GRCh37 6 71185377 71185377 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 19 66 0 ENST00000370479.3:c.180C>T p.Thr60= p.T60= ENST00000370479 60 acC/acT 0 +FAM157A UCSF GRCh37 3 197894633 197894633 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 25 1 ENST00000437428.2:n.794G>A *265* ENST00000437428 0 +FAM164A UCSF GRCh37 8 79601489 79601489 + missense_variant Missense_Mutation SNP T T A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 19 89 0 ENST00000263849.4:c.385T>A p.Phe129Ile p.F129I ENST00000263849 NM_016010.2 129 Ttc/Atc 0 +FAM166A UCSF GRCh37 9 140139640 140139640 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 6 9 0 ENST00000344774.4:c.553C>T p.Pro185Ser p.P185S ENST00000344774 NM_001001710.1 185 Ccc/Tcc 0 +FAM173B UCSF GRCh37 5 10227654 10227654 + missense_variant Missense_Mutation SNP C C T snp132_rs3177295 P01_Rec Untested WXS Illumina HiSeq 21 26 47 0 ENST00000511437.1:c.601G>A p.Glu201Lys p.E201K ENST00000511437 NM_199133.3 201 Gag/Aag 0 +FAM179B UCSF GRCh37 14 45481213 45481213 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 28 49 0 ENST00000361577.3:c.3173G>A p.Cys1058Tyr p.C1058Y ENST00000361577 NM_015091.2 1058 tGt/tAt 0 +FAM19A1 UCSF GRCh37 3 68466435 68466435 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 99 15 95 0 ENST00000478136.1:c.124G>A p.Gly42Arg p.G42R ENST00000478136 NM_213609.3 42 Ggg/Agg 0 +FAM26E UCSF GRCh37 6 116836991 116836991 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 19 105 0 ENST00000368599.3:c.769C>T p.Pro257Ser p.P257S ENST00000368599 NM_153711.2 257 Cct/Tct 0 +FAM46C UCSF GRCh37 1 118166409 118166409 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 8 38 0 ENST00000369448.3:c.919C>T p.Leu307Phe p.L307F ENST00000369448 NM_017709.3 307 Ctc/Ttc 0 +FAM48A UCSF GRCh37 13 37598537 37598537 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 8 64 0 ENST00000350612.6:c.1372G>A p.Gly458Ser p.G458S ENST00000350612 NM_001014286.2 458 Ggt/Agt 0 +FAM63A UCSF GRCh37 1 150973040 150973040 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 14 55 0 ENST00000361936.5:c.628G>A p.Val210Ile p.V210I ENST00000361936 NM_018379.4 210 Gtc/Atc 0 +FAM69B UCSF GRCh37 9 139617831 139617831 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 4 21 0 ENST00000371692.4:c.901G>A p.Ala301Thr p.A301T ENST00000371692 NM_152421.3 301 Gcc/Acc 0 +FAM71A UCSF GRCh37 1 212799161 212799161 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 26 0 ENST00000294829.3:c.942G>A p.Gly314= p.G314= ENST00000294829 NM_153606.3 314 ggG/ggA 0 +FAM71F2 UCSF GRCh37 7 128320204 128320204 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 13 42 0 ENST00000480462.1:c.734+1G>A p.X245_splice ENST00000480462 0 +FAM75A6 UCSF GRCh37 9 43627812 43627812 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 115 26 148 0 ENST00000332857.6:c.875C>T p.Ala292Val p.A292V ENST00000332857 NM_001145196.1 292 gCc/gTc 0 +FAM83B UCSF GRCh37 6 54806653 54806653 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 11 121 0 ENST00000306858.7:c.2884G>A p.Glu962Lys p.E962K ENST00000306858 NM_001010872.2 962 Gaa/Aaa 0 +FAM83B UCSF GRCh37 6 54806562 54806562 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 25 118 0 ENST00000306858.7:c.2793G>A p.Arg931= p.R931= ENST00000306858 NM_001010872.2 931 cgG/cgA 0 +FAM90A1 UCSF GRCh37 12 8374486 8374486 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 10 47 0 ENST00000307435.6:c.1327C>T p.Pro443Ser p.P443S ENST00000307435 443 Cca/Tca 0 +FANCA UCSF GRCh37 16 89805354 89805354 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 8 59 0 ENST00000389301.3:c.4196C>T p.Ala1399Val p.A1399V ENST00000389301 NM_000135.2 1399 gCt/gTt 0 +FARP1 UCSF GRCh37 13 99091386 99091386 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 23 35 0 ENST00000319562.6:c.2369G>A p.Ser790Asn p.S790N ENST00000319562 NM_005766.2 790 aGc/aAc 0 +FARS2 UCSF GRCh37 6 5369382 5369382 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 9 41 0 ENST00000274680.4:c.579G>A p.Gln193= p.Q193= ENST00000274680 NM_006567.3 193 caG/caA 0 +FASTKD1 UCSF GRCh37 2 170386416 170386416 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 6 52 0 ENST00000453153.2:c.2463C>T p.Asn821= p.N821= ENST00000453153 NM_024622.4 821 aaC/aaT 0 +FASTKD3 UCSF GRCh37 5 7863012 7863012 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 151 24 141 0 ENST00000264669.5:c.1623G>A p.Lys541= p.K541= ENST00000264669 NM_024091.3 541 aaG/aaA 0 +FAT1 UCSF GRCh37 4 187509963 187509963 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 37 14 78 0 ENST00000441802.2:c.13550C>T p.Ala4517Val p.A4517V ENST00000441802 NM_005245.3 4517 gCc/gTc 0 +FAT1 UCSF GRCh37 4 187542914 187542914 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 15 52 112 0 ENST00000441802.2:c.4826C>T p.Ser1609Phe p.S1609F ENST00000441802 NM_005245.3 1609 tCt/tTt 0 +FAT1 UCSF GRCh37 4 187627860 187627860 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 71 123 0 ENST00000441802.2:c.3122G>A p.Gly1041Glu p.G1041E ENST00000441802 NM_005245.3 1041 gGg/gAg 0 +FAT3 UCSF GRCh37 11 92086268 92086268 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 94 57 109 0 ENST00000298047.6:c.990G>A p.Lys330= p.K330= ENST00000298047 330 aaG/aaA 0 +FAT4 UCSF GRCh37 4 126240599 126240599 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 45 118 0 ENST00000394329.3:c.3033G>A p.Val1011= p.V1011= ENST00000394329 NM_024582.4 1011 gtG/gtA 0 +FBLN1 UCSF GRCh37 22 45959103 45959103 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 10 22 0 ENST00000327858.6:c.1698-11288C>T *566* ENST00000327858 NM_006486.2 0 +FBLN2 UCSF GRCh37 3 13613057 13613057 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 7 20 0 ENST00000295760.7:c.1202C>T p.Pro401Leu p.P401L ENST00000295760 NM_001998.2 401 cCc/cTc 0 +FBLN5 UCSF GRCh37 14 92349365 92349365 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 11 26 0 ENST00000342058.4:c.795G>A p.Gln265= p.Q265= ENST00000342058 NM_006329.3 265 caG/caA 0 +FBN1 UCSF GRCh37 15 48717668 48717668 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 12 49 0 ENST00000316623.5:c.7351G>A p.Ala2451Thr p.A2451T ENST00000316623 NM_000138.4 2451 Gct/Act 0 +FBN1 UCSF GRCh37 15 48757772 48757772 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 12 68 0 ENST00000316623.5:c.4935G>A p.Val1645= p.V1645= ENST00000316623 NM_000138.4 1645 gtG/gtA 0 +FBN3 UCSF GRCh37 19 8148151 8148151 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 19 37 0 ENST00000270509.2:c.7193C>T p.Ala2398Val p.A2398V ENST00000270509 NM_032447.3 2398 gCt/gTt 0 +FBXL5 UCSF GRCh37 4 15627527 15627527 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 24 66 0 ENST00000341285.3:c.1198G>A p.Ala400Thr p.A400T ENST00000341285 NM_001193534.1 400 Gcc/Acc 0 +FBXO18 UCSF GRCh37 10 5965617 5965617 + missense_variant Missense_Mutation SNP G G C NOVEL P01_Rec Untested WXS Illumina HiSeq 40 35 61 0 ENST00000362091.4:c.2356G>C p.Asp786His p.D786H ENST00000362091 NM_001258453.1 786 Gat/Cat 0 +FBXO34 UCSF GRCh37 14 55818571 55818571 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 59 107 0 ENST00000313833.4:c.1463G>A p.Gly488Asp p.G488D ENST00000313833 NM_017943.3 488 gGt/gAt 0 +FCER1A UCSF GRCh37 1 159273926 159273926 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 12 75 0 ENST00000368115.1:c.285C>T p.His95= p.H95= ENST00000368115 NM_002001.3 95 caC/caT 0 +FCHO2 UCSF GRCh37 5 72264375 72264375 + synonymous_variant Silent SNP A A T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 30 98 0 ENST00000430046.2:c.84A>T p.Gly28= p.G28= ENST00000430046 NM_138782.2 28 ggA/ggT 0 +FCRLA UCSF GRCh37 1 161680678 161680678 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 5 42 0 ENST00000367959.2:c.277C>T p.Pro93Ser p.P93S ENST00000367959 NM_001184866.1 93 Ccc/Tcc 0 +FER1L5 UCSF GRCh37 2 97370246 97370246 + downstream_gene_variant 3'Flank SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 113 65 128 0 ENST00000377079 NM_001142292.1 0 +FER1L6 UCSF GRCh37 8 125072466 125072466 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 22 78 0 ENST00000399018.1:c.2920G>A p.Asp974Asn p.D974N ENST00000399018 974 Gac/Aac 0 +FFAR2 UCSF GRCh37 19 35941280 35941280 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 13 23 0 ENST00000246549.2:c.664G>A p.Gly222Arg p.G222R ENST00000246549 NM_005306.2 222 Ggg/Agg 0 +FGA UCSF GRCh37 4 155507088 155507088 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 6 82 0 ENST00000302053.3:c.1493G>A p.Gly498Asp p.G498D ENST00000302053 NM_000508.3 498 gGc/gAc 0 +FH UCSF GRCh37 1 241671969 241671969 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 11 74 0 ENST00000366560.3:c.672G>A p.Glu224= p.E224= ENST00000366560 NM_000143.3 224 gaG/gaA 0 +FHOD3 UCSF GRCh37 18 34320685 34320685 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 7 48 0 ENST00000359247.4:c.3067C>T p.Pro1023Ser p.P1023S ENST00000359247 NM_001281739.1 1023 Cct/Tct 0 +FHOD3 UCSF GRCh37 18 34205546 34205546 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 19 40 0 ENST00000359247.4:c.1030G>A p.Ala344Thr p.A344T ENST00000359247 NM_001281739.1 344 Gcc/Acc 0 +FKBP10 UCSF GRCh37 17 39975921 39975921 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 5 19 0 ENST00000321562.4:c.1057G>A p.Gly353Arg p.G353R ENST00000321562 NM_021939.3 353 Gga/Aga 0 +FLII UCSF GRCh37 17 18157899 18157899 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 4 15 0 ENST00000327031.4:c.511C>T p.Arg171Cys p.R171C ENST00000327031 NM_002018.3 171 Cgc/Tgc 0 +FLII UCSF GRCh37 17 18149750 18149751 + inframe_insertion In_Frame_Ins INS - - CTC NOVEL P01_Rec Untested WXS Illumina HiSeq 6 0 ENST00000327031.4:c.3079_3080insGGA p.Glu1026_Asn1027insArg p.E1026_N1027insR ENST00000327031 NM_002018.3 1026 gag/gaGAGg 0 +FLNB UCSF GRCh37 3 58108939 58108939 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 27 81 0 ENST00000295956.4:c.3246G>A p.Glu1082= p.E1082= ENST00000295956 NM_001457.3 1082 gaG/gaA 0 +FMNL2 UCSF GRCh37 2 153496531 153496531 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 12 0 ENST00000288670.9:c.3006C>T p.Leu1002= p.L1002= ENST00000288670 NM_052905.3 1002 ctC/ctT 0 +FN1 UCSF GRCh37 2 216248897 216248897 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 46 82 0 ENST00000359671.1:c.4467C>T p.Ser1489= p.S1489= ENST00000359671 1489 agC/agT 0 +FNDC7 UCSF GRCh37 1 109276039 109276039 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 40 80 0 ENST00000370017.3:c.2025C>T p.Gly675= p.G675= ENST00000370017 NM_001144937.1 675 ggC/ggT 0 +FNIP1 UCSF GRCh37 5 131007197 131007197 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 25 93 0 ENST00000510461.1:c.2939+1G>A p.X980_splice ENST00000510461 NM_133372.2 0 +FOLH1 UCSF GRCh37 11 49221860 49221860 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 54 132 0 ENST00000256999.2:c.358C>T p.Pro120Ser p.P120S ENST00000256999 NM_004476.1 120 Cca/Tca 0 +FOLR1 UCSF GRCh37 11 71906504 71906504 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 45 70 0 ENST00000312293.4:c.357+1G>A p.X119_splice ENST00000312293 NM_016725.2 0 +FOSB UCSF GRCh37 19 45974128 45974128 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 5 10 14 0 ENST00000353609.3:c.368C>T p.Pro123Leu p.P123L ENST00000353609 NM_006732.2 123 cCt/cTt 0 +FOXB1 UCSF GRCh37 15 60297264 60297264 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 25 26 0 ENST00000396057.4:c.102G>A p.Leu34= p.L34= ENST00000396057 NM_012182.2 34 ctG/ctA 0 +FOXD2 UCSF GRCh37 1 47904249 47904249 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 18 34 0 ENST00000334793.5:c.442C>T p.Leu148= p.L148= ENST00000334793 NM_004474.3 148 Ctg/Ttg 0 +FOXF2 UCSF GRCh37 6 1390553 1390553 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 8 13 0 ENST00000259806.1:c.371G>A p.Ser124Asn p.S124N ENST00000259806 NM_001452.1 124 aGc/aAc 0 +FOXJ3 UCSF GRCh37 1 42657092 42657092 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 35 56 0 ENST00000361346.1:c.1233G>A p.Gln411= p.Q411= ENST00000361346 NM_014947.4 411 caG/caA 0 +FOXP2 UCSF GRCh37 7 114282468 114282468 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 35 39 0 ENST00000350908.4:c.779G>A p.Gly260Asp p.G260D ENST00000350908 260 gGc/gAc 0 +FOXR2 UCSF GRCh37 X 55650852 55650852 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 6 39 0 ENST00000339140.3:c.708G>A p.Trp236Ter p.W236* ENST00000339140 NM_198451.3 236 tgG/tgA 0 +FPGT UCSF GRCh37 1 74670257 74670257 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 55 87 0 ENST00000609362.1:c.526G>A p.Gly176Arg p.G176R ENST00000609362 176 Gga/Aga 0 +FRMD7 UCSF GRCh37 X 131212643 131212643 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 17 49 0 ENST00000298542.4:c.1402C>T p.Arg468Cys p.R468C ENST00000298542 NM_194277.2 468 Cgt/Tgt 0 +FRRS1 UCSF GRCh37 1 100195235 100195235 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 9 24 0 ENST00000287474.5:c.829G>A p.Gly277Arg p.G277R ENST00000287474 NM_001013660.2 277 Ggg/Agg 0 +FSD2 UCSF GRCh37 15 83437672 83437672 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 5 37 0 ENST00000334574.8:c.1513C>T p.Leu505= p.L505= ENST00000334574 505 Ctg/Ttg 0 +FSTL4 UCSF GRCh37 5 132561419 132561419 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 22 42 0 ENST00000265342.7:c.1108C>T p.Pro370Ser p.P370S ENST00000265342 NM_015082.1 370 Ccc/Tcc 0 +FUT9 UCSF GRCh37 6 96651854 96651854 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 27 62 0 ENST00000302103.5:c.823G>A p.Glu275Lys p.E275K ENST00000302103 NM_006581.3 275 Gaa/Aaa 0 +FYB UCSF GRCh37 5 39119705 39119705 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 83 43 151 0 ENST00000351578.6:c.2032G>A p.Glu678Lys p.E678K ENST00000351578 NM_199335.3 678 Gaa/Aaa 0 +FZD2 UCSF GRCh37 17 42636154 42636154 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 11 24 0 ENST00000315323.3:c.1098G>A p.Glu366= p.E366= ENST00000315323 NM_001466.3 366 gaG/gaA 0 +FZD7 UCSF GRCh37 2 202900847 202900847 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 26 0 ENST00000286201.1:c.1477C>T p.Gln493Ter p.Q493* ENST00000286201 NM_003507.1 493 Cag/Tag 0 +GAB1 UCSF GRCh37 4 144359379 144359379 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 12 43 0 ENST00000262994.4:c.821C>T p.Ser274Phe p.S274F ENST00000262994 NM_002039.3 274 tCt/tTt 0 +GADD45G UCSF GRCh37 9 92220582 92220582 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 4 10 0 ENST00000252506.6:c.156G>A p.Val52= p.V52= ENST00000252506 NM_006705.3 52 gtG/gtA 0 +GAL3ST4 UCSF GRCh37 7 99758503 99758503 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 6 27 0 ENST00000360039.4:c.509C>T p.Ser170Phe p.S170F ENST00000360039 NM_024637.4 170 tCc/tTc 0 +GALNT13 UCSF GRCh37 2 155099216 155099216 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 19 83 0 ENST00000392825.3:c.484C>T p.Leu162Phe p.L162F ENST00000392825 NM_052917.2 162 Ctc/Ttc 0 +GALNTL6 UCSF GRCh37 4 173961168 173961168 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 6 94 0 ENST00000506823.1:c.1723C>T p.Pro575Ser p.P575S ENST00000506823 NM_001034845.2 575 Cct/Tct 0 +GANAB UCSF GRCh37 11 62398076 62398076 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 28 31 0 ENST00000356638.3:c.1383G>A p.Arg461= p.R461= ENST00000356638 NM_198334.2 461 cgG/cgA 0 +GAS2L2 UCSF GRCh37 17 34072163 34072163 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 18 39 0 ENST00000254466.6:c.2353G>A p.Asp785Asn p.D785N ENST00000254466 NM_139285.3 785 Gac/Aac 0 +GAS6 UCSF GRCh37 13 114535664 114535664 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 18 22 0 ENST00000327773.6:c.896G>A p.Arg299Gln p.R299Q ENST00000327773 NM_000820.2 299 cGg/cAg 0 +GATM UCSF GRCh37 15 45656140 45656140 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 8 63 0 ENST00000396659.3:c.1117G>A p.Asp373Asn p.D373N ENST00000396659 NM_001482.2 373 Gat/Aat 0 +GBA2 UCSF GRCh37 9 35741757 35741757 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 4 35 0 ENST00000378103.3:c.698C>T p.Pro233Leu p.P233L ENST00000378103 NM_020944.2 233 cCc/cTc 0 +GBP3 UCSF GRCh37 1 89473487 89473487 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 35 96 0 ENST00000370481.4:c.1708C>T p.Leu570Phe p.L570F ENST00000370481 NM_018284.2 570 Ctt/Ttt 0 +GCDH UCSF GRCh37 19 13007724 13007724 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 5 10 0 ENST00000222214.5:c.853G>A p.Gly285Ser p.G285S ENST00000222214 NM_000159.3 285 Ggt/Agt 0 +GCHFR UCSF GRCh37 15 41059451 41059451 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 14 29 0 ENST00000260447.4:c.159C>T p.Pro53= p.P53= ENST00000260447 NM_005258.2 53 ccC/ccT 0 +GCK UCSF GRCh37 7 44187403 44187403 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 10 17 0 ENST00000403799.3:c.709G>A p.Glu237Lys p.E237K ENST00000403799 NM_000162.3 237 Gag/Aag 0 +GCLC UCSF GRCh37 6 53381010 53381010 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 25 58 0 ENST00000229416.6:c.457C>T p.Pro153Ser p.P153S ENST00000229416 NM_001197115.1 153 Cct/Tct 0 +GDF2 UCSF GRCh37 10 48413747 48413747 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 18 31 0 ENST00000249598.1:c.1121C>T p.Ala374Val p.A374V ENST00000249598 NM_016204.1 374 gCt/gTt 0 +GDPD1 UCSF GRCh37 17 57348345 57348345 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 43 98 0 ENST00000284116.4:c.759G>A p.Trp253Ter p.W253* ENST00000284116 NM_182569.3 253 tgG/tgA 0 +GEMIN5 UCSF GRCh37 5 154292500 154292500 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 7 52 0 ENST00000285873.7:c.1954G>A p.Asp652Asn p.D652N ENST00000285873 NM_001252156.1 652 Gat/Aat 0 +GFER UCSF GRCh37 16 2034833 2034833 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 5 25 0 ENST00000248114.6:c.344C>T p.Ala115Val p.A115V ENST00000248114 NM_005262.2 115 gCc/gTc 0 +GFRA2 UCSF GRCh37 8 21560357 21560357 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 6 12 0 ENST00000517328.1:c.1178G>A p.Ser393Asn p.S393N ENST00000517328 393 aGc/aAc 0 +GH2 UCSF GRCh37 17 61957741 61957741 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 31 75 0 ENST00000423893.2:c.594G>A p.Lys198= p.K198= ENST00000423893 198 aaG/aaA 0 +GIF UCSF GRCh37 11 59604702 59604702 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 30 63 0 ENST00000257248.2:c.816C>T p.Leu272= p.L272= ENST00000257248 NM_005142.2 272 ctC/ctT 0 +GIGYF1 UCSF GRCh37 7 100280950 100280950 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 4 17 0 ENST00000275732.5:c.2170G>A p.Glu724Lys p.E724K ENST00000275732 NM_022574.4 724 Gaa/Aaa 0 +GIT1 UCSF GRCh37 17 27903626 27903626 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 8 11 16 0 ENST00000225394.3:c.1294G>A p.Ala432Thr p.A432T ENST00000225394 NM_014030.3 432 Gcc/Acc 0 +GJA8 UCSF GRCh37 1 147380848 147380848 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 23 54 0 ENST00000369235.1:c.766G>A p.Ala256Thr p.A256T ENST00000369235 256 Gct/Act 0 +GLG1 UCSF GRCh37 16 74526903 74526903 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 11 81 0 ENST00000422840.2:c.1186G>A p.Ala396Thr p.A396T ENST00000422840 NM_001145667.1 396 Gcc/Acc 0 +GLT25D2 UCSF GRCh37 1 183913371 183913371 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 32 59 0 ENST00000361927.4:c.1356G>A p.Leu452= p.L452= ENST00000361927 NM_015101.2 452 ctG/ctA 0 +GMIP UCSF GRCh37 19 19750912 19750912 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 11 14 0 ENST00000203556.4:c.519G>A p.Gln173= p.Q173= ENST00000203556 NM_016573.2 173 caG/caA 0 +GNA14 UCSF GRCh37 9 80040551 80040551 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 85 44 132 0 ENST00000341700.6:c.804C>T p.Phe268= p.F268= ENST00000341700 NM_004297.3 268 ttC/ttT 0 +GNA15 UCSF GRCh37 19 3162822 3162822 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 13 15 0 ENST00000262958.3:c.930G>A p.Arg310= p.R310= ENST00000262958 NM_002068.2 310 agG/agA 0 +GNAL UCSF GRCh37 18 11872322 11872322 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 37 146 0 ENST00000269162.5:c.856G>A p.Glu286Lys p.E286K ENST00000269162 NM_001142339.2 286 Gaa/Aaa 0 +GNAS UCSF GRCh37 20 57415344 57415344 + intron_variant,non_coding_transcript_variant Intron SNP C C T snp132_rs1800901 P01_Rec Untested WXS Illumina HiSeq 25 3 20 0 ENST00000424094.2:n.819+1648G>A *273* ENST00000424094 0 +GNB5 UCSF GRCh37 15 52446146 52446146 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 27 60 0 ENST00000261837.7:c.366C>T p.Ser122= p.S122= ENST00000261837 NM_016194.3 122 agC/agT 0 +GNPNAT1 UCSF GRCh37 14 53248573 53248573 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 17 98 0 ENST00000216410.3:c.274G>A p.Val92Met p.V92M ENST00000216410 NM_198066.3 92 Gtg/Atg 0 +GOLGA1 UCSF GRCh37 9 127642825 127642825 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0015 P01_Rec Untested WXS Illumina HiSeq 70 35 72 0 ENST00000373555.4:c.2288G>A p.Arg763Gln p.R763Q ENST00000373555 NM_002077.3 763 cGg/cAg 0 +GOLGA4 UCSF GRCh37 3 37368568 37368568 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 25 145 0 ENST00000361924.2:c.5191C>T p.Gln1731Ter p.Q1731* ENST00000361924 NM_002078.4 1731 Cag/Tag 0 +GOLGA4 UCSF GRCh37 3 37367002 37367002 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 46 128 0 ENST00000361924.2:c.3625C>T p.Leu1209= p.L1209= ENST00000361924 NM_002078.4 1209 Ctg/Ttg 0 +GOLGA6C UCSF GRCh37 15 75562438 75562438 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 24 62 0 ENST00000300576.5:c.1980C>T p.Asn660= p.N660= ENST00000300576 NM_001164404.1 660 aaC/aaT 0 +GORASP2 UCSF GRCh37 2 171806194 171806194 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 32 108 0 ENST00000234160.4:c.290G>A p.Gly97Glu p.G97E ENST00000234160 NM_015530.4 97 gGa/gAa 0 +GPAA1 UCSF GRCh37 8 145139655 145139655 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 26 3 45 0 ENST00000355091.4:c.1041C>T p.Asn347= p.N347= ENST00000355091 NM_003801.3 347 aaC/aaT 0 +GPR107 UCSF GRCh37 9 132837988 132837988 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 22 0 ENST00000372406.1:c.215G>T p.Ser72Ile p.S72I ENST00000372406 NM_001136557.1 72 aGt/aTt 0 +GPR112 UCSF GRCh37 X 135405205 135405205 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 66 43 0 ENST00000370652.1:c.339C>T p.His113= p.H113= ENST00000370652 113 caC/caT 0 +GPR137C UCSF GRCh37 14 53098962 53098962 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 44 79 0 ENST00000321662.6:c.802G>A p.Val268Ile p.V268I ENST00000321662 NM_001099652.1 268 Gtc/Atc 0 +GPR158 UCSF GRCh37 10 25886967 25886967 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 141 21 110 0 ENST00000376351.3:c.2412G>A p.Glu804= p.E804= ENST00000376351 NM_020752.2 804 gaG/gaA 0 +GPR172A UCSF GRCh37 8 145583449 145583449 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 23 51 0 ENST00000329994.2:c.297G>A p.Trp99Ter p.W99* ENST00000329994 NM_024531.4 99 tgG/tgA 0 +GPR176 UCSF GRCh37 15 40093646 40093646 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 24 45 0 ENST00000561100.1:c.1235G>A p.Gly412Glu p.G412E ENST00000561100 NM_007223.2 412 gGa/gAa 0 +GPR19 UCSF GRCh37 12 12814250 12814250 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 45 142 0 ENST00000332427.2:c.1133C>T p.Pro378Leu p.P378L ENST00000332427 NM_006143.2 378 cCt/cTt 0 +GPR22 UCSF GRCh37 7 107115668 107115668 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 58 143 0 ENST00000304402.4:c.1163C>T p.Ser388Phe p.S388F ENST00000304402 NM_005295.2 388 tCt/tTt 0 +GPR37L1 UCSF GRCh37 1 202092434 202092434 + missense_variant Missense_Mutation SNP C C A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 6 22 1 ENST00000367282.5:c.343C>A p.Gln115Lys p.Q115K ENST00000367282 NM_004767.3 115 Cag/Aag 0 +GPR45 UCSF GRCh37 2 105858490 105858490 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 17 41 0 ENST00000258456.1:c.175G>A p.Val59Met p.V59M ENST00000258456 NM_007227.3 59 Gtg/Atg 0 +GPR64 UCSF GRCh37 X 19032072 19032072 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 8 28 0 ENST00000379869.3:c.831C>T p.Thr277= p.T277= ENST00000379869 NM_001079858.2 277 acC/acT 0 +GPRC6A UCSF GRCh37 6 117127574 117127574 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 21 51 0 ENST00000310357.3:c.1294G>A p.Ala432Thr p.A432T ENST00000310357 NM_148963.2 432 Gct/Act 0 +GPRC6A UCSF GRCh37 6 117130700 117130700 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 27 56 0 ENST00000310357.3:c.275G>A p.Gly92Glu p.G92E ENST00000310357 NM_148963.2 92 gGa/gAa 0 +GPRC6A UCSF GRCh37 6 117127942 117127942 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 54 120 0 ENST00000310357.3:c.926C>T p.Thr309Ile p.T309I ENST00000310357 NM_148963.2 309 aCc/aTc 0 +GPX4 UCSF GRCh37 19 1106459 1106459 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 5 21 0 ENST00000354171.8:c.561+1G>A p.X187_splice ENST00000354171 NM_001039847.1 0 +GPX6 UCSF GRCh37 6 28478643 28478643 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 18 49 0 ENST00000361902.1:c.126G>A p.Glu42= p.E42= ENST00000361902 NM_182701.1 42 gaG/gaA 0 +GREB1 UCSF GRCh37 2 11765424 11765424 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 171 61 112 0 ENST00000234142.5:c.4292G>A p.Gly1431Asp p.G1431D ENST00000234142 1431 gGt/gAt 0 +GRHL1 UCSF GRCh37 2 10104452 10104452 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 19 43 0 ENST00000324907.9:c.992C>T p.Ala331Val p.A331V ENST00000324907 NM_198182.2 331 gCt/gTt 0 +GRID1 UCSF GRCh37 10 87406962 87406962 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 35 75 0 ENST00000327946.7:c.2190G>A p.Arg730= p.R730= ENST00000327946 NM_017551.2 730 agG/agA 0 +GRID2 UCSF GRCh37 4 94138039 94138039 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 27 116 0 ENST00000282020.4:c.940G>A p.Asp314Asn p.D314N ENST00000282020 NM_001510.2 314 Gat/Aat 0 +GRID2 UCSF GRCh37 4 94376896 94376896 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 27 70 0 ENST00000282020.4:c.1629C>T p.Tyr543= p.Y543= ENST00000282020 NM_001510.2 543 taC/taT 0 +GRID2 UCSF GRCh37 4 94316793 94316793 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 35 98 0 ENST00000282020.4:c.1281G>A p.Gly427= p.G427= ENST00000282020 NM_001510.2 427 ggG/ggA 0 +GRIK1 UCSF GRCh37 21 31062291 31062291 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 11 35 0 ENST00000399907.1:c.301G>A p.Ala101Thr p.A101T ENST00000399907 NM_000830.3 101 Gct/Act 0 +GRIN1 UCSF GRCh37 9 140058244 140058244 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 17 33 0 ENST00000371561.3:c.2477C>T p.Ala826Val p.A826V ENST00000371561 NM_007327.3 826 gCc/gTc 0 +GRIP2 UCSF GRCh37 3 14536441 14536441 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 18 0 ENST00000273083.3:n.2945C>T *982* ENST00000273083 0 +GRM1 UCSF GRCh37 6 146720776 146720776 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 21 18 0 ENST00000282753.1:c.2601C>T p.Cys867= p.C867= ENST00000282753 NM_001278067.1 867 tgC/tgT 0 +GRM1 UCSF GRCh37 6 146747734 146747734 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 24 62 0 ENST00000282753.1:c.2661-7274G>A *887* ENST00000282753 NM_001278067.1 0 +GRM2 UCSF GRCh37 3 51749551 51749551 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 18 22 0 ENST00000395052.3:c.1762G>A p.Val588Ile p.V588I ENST00000395052 NM_000839.3 588 Gtc/Atc 0 +GRM8 UCSF GRCh37 7 126882895 126882895 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 26 82 0 ENST00000339582.2:c.364G>A p.Ala122Thr p.A122T ENST00000339582 122 Gca/Aca 0 +GRTP1 UCSF GRCh37 13 113980369 113980369 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 10 17 0 ENST00000375431.4:c.600C>T p.Asp200= p.D200= ENST00000375431 NM_024719.2 200 gaC/gaT 0 +GRXCR1 UCSF GRCh37 4 42895398 42895398 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 77 48 89 0 ENST00000399770.2:c.115T>C p.Ser39Pro p.S39P ENST00000399770 NM_001080476.2 39 Tca/Cca 0 +GRXCR2 UCSF GRCh37 5 145239346 145239346 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 23 57 0 ENST00000377976.1:c.697C>T p.Pro233Ser p.P233S ENST00000377976 NM_001080516.1 233 Cct/Tct 0 +GSG2 UCSF GRCh37 17 3628523 3628523 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 35 82 0 ENST00000325418.4:c.1294G>A p.Ala432Thr p.A432T ENST00000325418 NM_031965.2 432 Gct/Act 0 +GTSE1 UCSF GRCh37 22 46708062 46708062 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 30 61 0 ENST00000454366.1:c.787C>T p.Pro263Ser p.P263S ENST00000454366 NM_016426.6 263 Cct/Tct 0 +GXYLT1 UCSF GRCh37 12 42481737 42481737 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 25 60 0 ENST00000398675.3:c.1174G>A p.Asp392Asn p.D392N ENST00000398675 NM_173601.1 392 Gat/Aat 0 +GXYLT1 UCSF GRCh37 12 42491349 42491349 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 124 14 111 0 ENST00000398675.3:c.1056C>T p.Cys352= p.C352= ENST00000398675 NM_173601.1 352 tgC/tgT 0 +HAP1 UCSF GRCh37 17 39881070 39881070 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 93 11 61 0 ENST00000310778.5:c.1899C>T p.Asn633= p.N633= ENST00000310778 633 aaC/aaT 0 +HBS1L UCSF GRCh37 6 135358639 135358639 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 12 69 0 ENST00000367837.5:c.430+2072G>A *144* ENST00000367837 NM_006620.3 0 +HBS1L UCSF GRCh37 6 135360725 135360725 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 100 22 125 0 ENST00000367837.5:c.416G>A p.Gly139Glu p.G139E ENST00000367837 NM_006620.3 139 gGa/gAa 0 +HDAC4 UCSF GRCh37 2 239990216 239990216 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 5 16 0 ENST00000345617.3:c.2823C>T p.Thr941= p.T941= ENST00000345617 NM_006037.3 941 acC/acT 0 +HEATR4 UCSF GRCh37 14 73965842 73965842 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 37 73 0 ENST00000334988.2:c.2289G>A p.Val763= p.V763= ENST00000334988 NM_203309.2 763 gtG/gtA 0 +HEATR5A UCSF GRCh37 14 31852965 31852965 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 53 0 ENST00000389961.3:c.1340G>A p.Ser447Asn p.S447N ENST00000389961 447 aGt/aAt 0 +HEATR6 UCSF GRCh37 17 58123567 58123567 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 36 103 0 ENST00000184956.6:c.2793C>T p.Ala931= p.A931= ENST00000184956 NM_022070.4 931 gcC/gcT 0 +HECTD1 UCSF GRCh37 14 31592144 31592144 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 107 20 111 0 ENST00000399332.1:c.5091G>A p.Glu1697= p.E1697= ENST00000399332 NM_015382.2 1697 gaG/gaA 0 +HECTD1 UCSF GRCh37 14 31597876 31597876 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 35 71 0 ENST00000399332.1:c.4701C>T p.Ser1567= p.S1567= ENST00000399332 NM_015382.2 1567 agC/agT 0 +HELZ UCSF GRCh37 17 65147165 65147165 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 38 93 0 ENST00000358691.5:c.2353C>T p.Pro785Ser p.P785S ENST00000358691 NM_014877.3 785 Cct/Tct 0 +HERC1 UCSF GRCh37 15 63986511 63986511 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 118 15 98 0 ENST00000443617.2:c.5480G>A p.Gly1827Glu p.G1827E ENST00000443617 NM_003922.3 1827 gGg/gAg 0 +HERC4 UCSF GRCh37 10 69748441 69748441 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 18 142 0 ENST00000395198.3:c.1785G>A p.Lys595= p.K595= ENST00000395198 NM_022079.2 595 aaG/aaA 0 +HGSNAT UCSF GRCh37 8 43046714 43046714 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 45 15 56 0 ENST00000379644.4:c.1226T>C p.Leu409Pro p.L409P ENST00000379644 NM_152419.2 409 cTc/cCc 0 +HINFP UCSF GRCh37 11 119003262 119003262 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 8 36 0 ENST00000350777.2:c.733C>T p.Arg245Trp p.R245W ENST00000350777 NM_198971.2 245 Cgg/Tgg 0 +HINT3 UCSF GRCh37 6 126296071 126296071 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 44 106 0 ENST00000229633.5:c.468C>T p.Gly156= p.G156= ENST00000229633 NM_138571.4 156 ggC/ggT 0 +HIPK1 UCSF GRCh37 1 114512655 114512655 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 102 24 54 0 ENST00000369558.1:c.2849G>A p.Ser950Asn p.S950N ENST00000369558 950 aGc/aAc 0 +HIRA UCSF GRCh37 22 19347002 19347002 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 5 18 0 ENST00000263208.5:c.2091C>T p.Ser697= p.S697= ENST00000263208 NM_003325.3 697 agC/agT 0 +HIVEP1 UCSF GRCh37 6 12123966 12123966 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 105 14 58 0 ENST00000379388.2:c.3938C>T p.Ser1313Phe p.S1313F ENST00000379388 NM_002114.2 1313 tCt/tTt 0 +HIVEP1 UCSF GRCh37 6 12124361 12124361 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 143 30 112 0 ENST00000379388.2:c.4333C>T p.Pro1445Ser p.P1445S ENST00000379388 NM_002114.2 1445 Cct/Tct 0 +HIVEP1 UCSF GRCh37 6 12122439 12122439 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 119 44 103 0 ENST00000379388.2:c.2411G>A p.Ser804Asn p.S804N ENST00000379388 NM_002114.2 804 aGt/aAt 0 +HLA-B UCSF GRCh37 6 31323134 31323134 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.020,snp132_rs1050240 P01_Rec Untested WXS Illumina HiSeq 62 10 26 1 ENST00000412585.2:c.855A>G p.Val285= p.V285= ENST00000412585 NM_005514.6 285 gtA/gtG 0 +HLA-C UCSF GRCh37 6 31239616 31239616 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.000,1000g2011may_all_0.0851,snp132_rs1050445 P01_Rec Untested WXS Illumina HiSeq 26 4 11 0 ENST00000376228.5:c.103G>T p.Ala35Ser p.A35S ENST00000376228 NM_002117.5 35 Gcc/Tcc 0 +HLA-DMA UCSF GRCh37 6 32917118 32917118 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 36 7 20 0 ENST00000374843.4:c.711T>C p.Phe237= p.F237= ENST00000374843 NM_006120.3 237 ttT/ttC 0 +HLA-DPB1 UCSF GRCh37 6 33053616 33053616 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 23 34 0 ENST00000418931.2:c.707G>A p.Gly236Glu p.G236E ENST00000418931 NM_002121.5 236 gGg/gAg 0 +HMCN1 UCSF GRCh37 1 186072691 186072691 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 30 57 0 ENST00000271588.4:c.10661G>A p.Gly3554Glu p.G3554E ENST00000271588 NM_031935.2 3554 gGa/gAa 0 +HMGCS2 UCSF GRCh37 1 120301844 120301844 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 9 65 0 ENST00000369406.3:c.747G>A p.Glu249= p.E249= ENST00000369406 NM_005518.3 249 gaG/gaA 0 +HMOX1 UCSF GRCh37 22 35789569 35789569 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 38 57 0 ENST00000216117.8:c.845C>T p.Ala282Val p.A282V ENST00000216117 NM_002133.2 282 gCt/gTt 0 +HNRNPA1 UCSF GRCh37 12 54677599 54677599 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 122 75 111 0 ENST00000340913.6:c.911G>A p.Ser304Asn p.S304N ENST00000340913 NM_002136.2 304 aGc/aAc 0 +HOGA1 UCSF GRCh37 10 99359865 99359865 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 16 58 0 ENST00000370646.4:c.645G>A p.Gln215= p.Q215= ENST00000370646 NM_138413.3 215 caG/caA 0 +HOMEZ UCSF GRCh37 14 23745354 23745354 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 123 16 72 0 ENST00000357460.5:c.1083G>A p.Lys361= p.K361= ENST00000357460 NM_020834.2 361 aaG/aaA 0 +HOOK2 UCSF GRCh37 19 12881784 12881784 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 17 0 ENST00000397668.3:c.864G>A p.Gln288= p.Q288= ENST00000397668 NM_013312.2 288 caG/caA 0 +HOOK3 UCSF GRCh37 8 42819560 42819560 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 16 107 0 ENST00000307602.4:c.722G>A p.Gly241Glu p.G241E ENST00000307602 NM_032410.3 241 gGa/gAa 0 +HOXA4 UCSF GRCh37 7 27169181 27169181 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 20 24 0 ENST00000360046.5:c.626G>A p.Ser209Asn p.S209N ENST00000360046 NM_002141.4 209 aGt/aAt 0 +HOXB13 UCSF GRCh37 17 46804157 46804157 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 27 35 0 ENST00000290295.7:c.850C>T p.Pro284Ser p.P284S ENST00000290295 NM_006361.5 284 Cct/Tct 0 +HOXC5 UCSF GRCh37 12 54426994 54426994 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 6 39 0 ENST00000312492.2:c.88G>A p.Ala30Thr p.A30T ENST00000312492 NM_018953.2 30 Gcc/Acc 0 +HPD UCSF GRCh37 12 122284968 122284968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 21 58 0 ENST00000289004.4:c.749C>T p.Ser250Phe p.S250F ENST00000289004 NM_002150.2 250 tCc/tTc 0 +HR UCSF GRCh37 8 21979143 21979143 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 11 20 0 ENST00000381418.4:c.2186C>T p.Thr729Ile p.T729I ENST00000381418 NM_005144.4 729 aCc/aTc 0 +HSF4 UCSF GRCh37 16 67201407 67201407 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 33 38 0 ENST00000264009.8:c.759C>T p.Ser253= p.S253= ENST00000264009 NM_001040667.2 253 agC/agT 0 +HSPA5 UCSF GRCh37 9 127998941 127998941 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 33 76 0 ENST00000324460.6:c.1895G>A p.Ser632Asn p.S632N ENST00000324460 NM_005347.4 632 aGc/aAc 0 +HSPG2 UCSF GRCh37 1 22203049 22203049 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 6 11 0 ENST00000374695.3:c.2782G>A p.Gly928Ser p.G928S ENST00000374695 NM_005529.5 928 Ggt/Agt 0 +HSPH1 UCSF GRCh37 13 31712963 31712963 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 33 93 0 ENST00000320027.5:c.2163G>A p.Gln721= p.Q721= ENST00000320027 NM_006644.2 721 caG/caA 0 +HYDIN UCSF GRCh37 16 70902603 70902603 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 15 44 0 ENST00000393567.2:c.11180G>A p.Arg3727Lys p.R3727K ENST00000393567 NM_001270974.1 3727 aGg/aAg 0 +HYOU1 UCSF GRCh37 11 118923365 118923365 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 8 15 0 ENST00000404233.3:c.971C>T p.Ala324Val p.A324V ENST00000404233 NM_001130991.1 324 gCt/gTt 0 +IARS2 UCSF GRCh37 1 220307830 220307830 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 16 51 0 ENST00000366922.1:c.1708G>A p.Ala570Thr p.A570T ENST00000366922 570 Gca/Aca 0 +IBTK UCSF GRCh37 6 82882227 82882227 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 10 84 0 ENST00000306270.7:c.3800C>T p.Pro1267Leu p.P1267L ENST00000306270 NM_015525.2 1267 cCc/cTc 0 +ICK UCSF GRCh37 6 52870001 52870001 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 22 51 0 ENST00000350082.5:c.1845C>T p.Ala615= p.A615= ENST00000350082 NM_014920.3 615 gcC/gcT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 47 22 74 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFFO1 UCSF GRCh37 12 6649714 6649714 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 15 0 ENST00000396840.2:c.1615C>T p.Pro539Ser p.P539S ENST00000396840 539 Ccg/Tcg 0 +IFT122 UCSF GRCh37 3 129195505 129195505 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 4 47 0 ENST00000348417.2:c.1009-1G>A p.X337_splice ENST00000348417 NM_052989.2 0 +IGF2BP3 UCSF GRCh37 7 23358756 23358756 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 94 13 104 0 ENST00000258729.3:c.1320+1G>A p.X440_splice ENST00000258729 NM_006547.2 0 +IGFBP3 UCSF GRCh37 7 45956908 45956908 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 35 42 0 ENST00000275521.6:c.534G>A p.Gly178= p.G178= ENST00000275521 NM_001013398.1 178 ggG/ggA 0 +IGFBP5 UCSF GRCh37 2 217543670 217543670 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 14 25 0 ENST00000233813.4:c.470G>A p.Arg157Lys p.R157K ENST00000233813 NM_000599.3 157 aGa/aAa 0 +IGSF10 UCSF GRCh37 3 151166242 151166242 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 63 105 0 ENST00000282466.3:c.1527G>A p.Trp509Ter p.W509* ENST00000282466 NM_178822.4 509 tgG/tgA 0 +IGSF21 UCSF GRCh37 1 18692125 18692125 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 8 23 0 ENST00000251296.1:c.949G>A p.Ala317Thr p.A317T ENST00000251296 NM_032880.4 317 Gcc/Acc 0 +IGSF3 UCSF GRCh37 1 117131413 117131413 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 9 12 0 ENST00000369486.3:c.2343C>T p.Tyr781= p.Y781= ENST00000369486 NM_001007237.2 781 taC/taT 0 +IGSF5 UCSF GRCh37 21 41142851 41142851 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 8 42 0 ENST00000380588.4:c.427G>A p.Glu143Lys p.E143K ENST00000380588 NM_001080444.1 143 Gag/Aag 0 +IKBKB UCSF GRCh37 8 42179941 42179941 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 41 49 0 ENST00000520810.1:c.1915G>A p.Asp639Asn p.D639N ENST00000520810 NM_001556.2 639 Gat/Aat 0 +IL12RB2 UCSF GRCh37 1 67796484 67796484 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 75 69 120 0 ENST00000262345.1:c.949C>T p.Pro317Ser p.P317S ENST00000262345 NM_001559.2 317 Cca/Tca 0 +IL13RA2 UCSF GRCh37 X 114245322 114245322 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 7 64 0 ENST00000243213.1:c.591C>T p.Cys197= p.C197= ENST00000243213 NM_000640.2 197 tgC/tgT 0 +IL1R1 UCSF GRCh37 2 102789257 102789257 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 19 77 0 ENST00000410023.1:c.950C>T p.Thr317Ile p.T317I ENST00000410023 317 aCa/aTa 0 +IL1R2 UCSF GRCh37 2 102626154 102626154 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 40 96 0 ENST00000332549.3:c.198C>T p.Asn66= p.N66= ENST00000332549 NM_004633.3 66 aaC/aaT 0 +IL1RAPL2 UCSF GRCh37 X 104728355 104728355 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 5 41 0 ENST00000372582.1:c.748C>T p.Pro250Ser p.P250S ENST00000372582 NM_017416.1 250 Cca/Tca 0 +IL1RN UCSF GRCh37 2 113885288 113885288 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 30 53 0 ENST00000409930.3:c.87G>A p.Gly29= p.G29= ENST00000409930 NM_173842.2 29 ggG/ggA 0 +IL26 UCSF GRCh37 12 68618974 68618974 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 11 102 0 ENST00000229134.4:c.318C>T p.Arg106= p.R106= ENST00000229134 NM_018402.1 106 cgC/cgT 0 +IL2RA UCSF GRCh37 10 6063440 6063440 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 22 49 0 ENST00000379959.3:c.583+1G>A p.X195_splice ENST00000379959 NM_000417.2 0 +IL3 UCSF GRCh37 5 131398045 131398045 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 142 40 97 0 ENST00000296870.2:c.245G>A p.Arg82Lys p.R82K ENST00000296870 NM_000588.3 82 aGg/aAg 0 +IL36B UCSF GRCh37 2 113788669 113788669 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 27 58 0 ENST00000259213.4:c.77G>A p.Gly26Glu p.G26E ENST00000259213 NM_014438.4 26 gGa/gAa 0 +IL6R UCSF GRCh37 1 154401885 154401885 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 5 21 0 ENST00000368485.3:c.299G>A p.Gly100Asp p.G100D ENST00000368485 NM_000565.3 100 gGc/gAc 0 +IMP5 UCSF GRCh37 17 43922988 43922988 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 17 28 0 ENST00000329196.5:c.716C>T p.Ala239Val p.A239V ENST00000329196 NM_175882.2 239 gCc/gTc 0 +INPP5D UCSF GRCh37 2 234085968 234085968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 30 61 0 ENST00000445964.1:c.910G>A p.Val304Met p.V304M ENST00000445964 304 Gtg/Atg 0 +INPP5F UCSF GRCh37 10 121586293 121586293 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 25 119 0 ENST00000361976.2:c.2400C>T p.Leu800= p.L800= ENST00000361976 NM_014937.3 800 ctC/ctT 0 +INPPL1 UCSF GRCh37 11 71942216 71942216 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 16 50 0 ENST00000298229.2:c.1480G>A p.Asp494Asn p.D494N ENST00000298229 NM_001567.3 494 Gat/Aat 0 +INSM2 UCSF GRCh37 14 36004874 36004874 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 9 13 0 ENST00000307169.3:c.1416C>T p.Cys472= p.C472= ENST00000307169 NM_032594.3 472 tgC/tgT 0 +INSRR UCSF GRCh37 1 156819111 156819111 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 21 31 0 ENST00000368195.3:c.1371G>A p.Glu457= p.E457= ENST00000368195 NM_014215.2 457 gaG/gaA 0 +INTS1 UCSF GRCh37 7 1523477 1523477 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 5 25 0 ENST00000404767.3:c.3442G>A p.Asp1148Asn p.D1148N ENST00000404767 NM_001080453.2 1148 Gac/Aac 0 +IP6K3 UCSF GRCh37 6 33690912 33690912 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 76 9 44 0 ENST00000293756.4:c.818G>A p.Arg273Lys p.R273K ENST00000293756 NM_054111.4 273 aGa/aAa 0 +IPO11 UCSF GRCh37 5 61762983 61762983 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 28 97 0 ENST00000325324.6:c.542C>T p.Ala181Val p.A181V ENST00000325324 NM_016338.4 181 gCc/gTc 0 +IPO9 UCSF GRCh37 1 201823974 201823974 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 8 68 0 ENST00000361565.4:c.834C>T p.Asn278= p.N278= ENST00000361565 NM_018085.4 278 aaC/aaT 0 +IRAK3 UCSF GRCh37 12 66620604 66620604 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 109 26 130 0 ENST00000261233.4:c.755G>A p.Arg252Lys p.R252K ENST00000261233 NM_007199.2 252 aGa/aAa 0 +IREB2 UCSF GRCh37 15 78758799 78758799 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 6 78 0 ENST00000258886.8:c.597C>T p.Ile199= p.I199= ENST00000258886 NM_004136.2 199 atC/atT 0 +IRF2 UCSF GRCh37 4 185310032 185310032 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 13 71 0 ENST00000393593.3:c.930C>T p.Asp310= p.D310= ENST00000393593 NM_002199.3 310 gaC/gaT 0 +IRS4 UCSF GRCh37 X 107977413 107977413 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 7 39 0 ENST00000372129.2:c.2162C>T p.Ala721Val p.A721V ENST00000372129 NM_003604.2 721 gCt/gTt 0 +ISLR UCSF GRCh37 15 74467567 74467567 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 11 14 0 ENST00000249842.3:c.368C>T p.Ala123Val p.A123V ENST00000249842 NM_005545.3 123 gCc/gTc 0 +ISM1 UCSF GRCh37 20 13251231 13251231 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 38 86 0 ENST00000262487.4:c.219C>T p.Asp73= p.D73= ENST00000262487 NM_080826.1 73 gaC/gaT 0 +ITGA7 UCSF GRCh37 12 56092242 56092242 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 9 17 0 ENST00000555728.1:c.1249C>T p.Leu417Phe p.L417F ENST00000555728 417 Ctc/Ttc 0 +ITGA8 UCSF GRCh37 10 15617487 15617487 + splice_donor_variant Splice_Site SNP C C A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 10 38 1 ENST00000378076.3:c.2478+1G>T p.X826_splice ENST00000378076 NM_003638.1 0 +ITGA8 UCSF GRCh37 10 15639251 15639251 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 13 104 0 ENST00000378076.3:c.2166G>A p.Arg722= p.R722= ENST00000378076 NM_003638.1 722 agG/agA 0 +ITGAD UCSF GRCh37 16 31419115 31419115 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 9 25 0 ENST00000389202.2:c.887C>T p.Ala296Val p.A296V ENST00000389202 NM_005353.2 296 gCc/gTc 0 +ITGAL UCSF GRCh37 16 30507834 30507834 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 22 30 0 ENST00000356798.6:c.1779G>A p.Gly593= p.G593= ENST00000356798 NM_002209.2 593 ggG/ggA 0 +ITGAL UCSF GRCh37 16 30529162 30529162 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 9 43 0 ENST00000356798.6:c.3078G>A p.Arg1026= p.R1026= ENST00000356798 NM_002209.2 1026 agG/agA 0 +ITGAX UCSF GRCh37 16 31366602 31366602 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 3 14 0 ENST00000268296.4:c.27C>T p.Leu9= p.L9= ENST00000268296 NM_000887.3 9 ctC/ctT 0 +ITGB2 UCSF GRCh37 21 46311833 46311833 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 9 14 0 ENST00000302347.5:c.1303G>A p.Asp435Asn p.D435N ENST00000302347 NM_000211.3 435 Gac/Aac 0 +ITPKA UCSF GRCh37 15 41794648 41794648 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 12 13 0 ENST00000260386.5:c.1057G>A p.Glu353Lys p.E353K ENST00000260386 NM_002220.2 353 Gag/Aag 0 +IYD UCSF GRCh37 6 150713488 150713488 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 50 116 0 ENST00000344419.3:c.378C>T p.Ala126= p.A126= ENST00000344419 NM_203395.2 126 gcC/gcT 0 +JAKMIP1 UCSF GRCh37 4 6043926 6043926 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 49 76 0 ENST00000409021.3:c.2057C>T p.Ala686Val p.A686V ENST00000409021 NM_001099433.1 686 gCc/gTc 0 +JAKMIP1 UCSF GRCh37 4 6080714 6080714 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 10 21 0 ENST00000282924.5:c.1254G>A p.Arg418= p.R418= ENST00000282924 NM_144720.3 418 cgG/cgA 0 +JMJD1C UCSF GRCh37 10 64958453 64958453 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 31 75 0 ENST00000399262.2:c.5311G>A p.Asp1771Asn p.D1771N ENST00000399262 NM_032776.1 1771 Gat/Aat 0 +JRKL UCSF GRCh37 11 96123920 96123920 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 21 71 0 ENST00000332349.4:c.107G>A p.Gly36Glu p.G36E ENST00000332349 NM_001261833.1 36 gGa/gAa 0 +KANK1 UCSF GRCh37 9 732573 732573 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 42 94 0 ENST00000382297.2:c.3201G>A p.Met1067Ile p.M1067I ENST00000382297 NM_001256877.1 1067 atG/atA 0 +KAT5 UCSF GRCh37 11 65480933 65480933 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 4 14 0 ENST00000377046.3:c.400C>T p.Leu134Phe p.L134F ENST00000377046 NM_006388.3 134 Ctc/Ttc 0 +KCMF1 UCSF GRCh37 2 85276592 85276592 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 69 76 0 ENST00000409785.4:c.705G>A p.Gln235= p.Q235= ENST00000409785 NM_020122.4 235 caG/caA 0 +KCNC1 UCSF GRCh37 11 17794140 17794140 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 21 96 0 ENST00000379472.3:c.1499G>A p.Arg500Lys p.R500K ENST00000379472 NM_004976.4 500 aGa/aAa 0 +KCNC4 UCSF GRCh37 1 110765873 110765873 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 10 32 0 ENST00000369787.3:c.966C>T p.Ile322= p.I322= ENST00000369787 NM_004978.4 322 atC/atT 0 +KCNE1 UCSF GRCh37 21 35821789 35821789 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 12 19 0 ENST00000337385.3:c.144C>T p.Leu48= p.L48= ENST00000337385 NM_001270403.1 48 ctC/ctT 0 +KCNH2 UCSF GRCh37 7 150648065 150648065 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 7 14 0 ENST00000262186.5:c.2089C>T p.Leu697Phe p.L697F ENST00000262186 NM_000238.3 697 Ctc/Ttc 0 +KCNH6 UCSF GRCh37 17 61613299 61613299 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 3 16 0 ENST00000583023.1:c.1371C>T p.Pro457= p.P457= ENST00000583023 NM_030779.3 457 ccC/ccT 0 +KCNJ1 UCSF GRCh37 11 128709396 128709396 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 37 81 0 ENST00000392664.2:c.800C>T p.Thr267Ile p.T267I ENST00000392664 NM_000220.4 267 aCa/aTa 0 +KCNJ13 UCSF GRCh37 2 233633281 233633281 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 103 18 90 0 ENST00000233826.3:c.703C>T p.Pro235Ser p.P235S ENST00000233826 NM_002242.4 235 Cca/Tca 0 +KCNJ5 UCSF GRCh37 11 128781514 128781514 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 12 78 0 ENST00000338350.4:c.346G>A p.Gly116Ser p.G116S ENST00000338350 116 Ggt/Agt 0 +KCNK3 UCSF GRCh37 2 26950561 26950561 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 26 57 0 ENST00000302909.3:c.310G>A p.Asp104Asn p.D104N ENST00000302909 NM_002246.2 104 Gat/Aat 0 +KCNK6 UCSF GRCh37 19 38817548 38817548 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 18 57 0 ENST00000263372.3:c.638C>T p.Ser213Phe p.S213F ENST00000263372 NM_004823.1 213 tCc/tTc 0 +KCNK6 UCSF GRCh37 19 38817379 38817379 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 30 61 0 ENST00000263372.3:c.469C>T p.Leu157= p.L157= ENST00000263372 NM_004823.1 157 Ctg/Ttg 0 +KCNMA1 UCSF GRCh37 10 79397125 79397125 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 5 9 0 ENST00000286628.8:c.276C>T p.Ala92= p.A92= ENST00000286628 NM_001161352.1 92 gcC/gcT 0 +KCNQ3 UCSF GRCh37 8 133192525 133192525 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 5 26 0 ENST00000388996.4:c.656G>A p.Gly219Asp p.G219D ENST00000388996 NM_004519.3 219 gGc/gAc 0 +KCTD18 UCSF GRCh37 2 201369581 201369581 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 9 60 0 ENST00000359878.3:c.262C>T p.Leu88= p.L88= ENST00000359878 NM_152387.2 88 Cta/Tta 0 +KDM6B UCSF GRCh37 17 7755606 7755606 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 23 0 ENST00000448097.2:c.4420G>A p.Ala1474Thr p.A1474T ENST00000448097 1474 Gcc/Acc 0 +KDM6B UCSF GRCh37 17 7750671 7750671 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 13 18 0 ENST00000448097.2:c.1158C>T p.Ala386= p.A386= ENST00000448097 386 gcC/gcT 0 +KHDRBS1 UCSF GRCh37 1 32503455 32503455 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 43 87 0 ENST00000327300.7:c.925C>T p.Pro309Ser p.P309S ENST00000327300 NM_006559.2 309 Cct/Tct 0 +KHDRBS1 UCSF GRCh37 1 32498872 32498872 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 24 69 0 ENST00000327300.7:c.708C>T p.Pro236= p.P236= ENST00000327300 NM_006559.2 236 ccC/ccT 0 +KHDRBS2 UCSF GRCh37 6 62611213 62611213 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 27 79 0 ENST00000281156.4:c.547G>A p.Asp183Asn p.D183N ENST00000281156 NM_152688.2 183 Gac/Aac 0 +KHSRP UCSF GRCh37 19 6416415 6416415 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 9 12 0 ENST00000398148.3:c.1492C>T p.Pro498Ser p.P498S ENST00000398148 NM_003685.2 498 Cct/Tct 0 +KIAA0100 UCSF GRCh37 17 26962186 26962186 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 54 126 1 ENST00000528896.2:c.2419C>T p.Pro807Ser p.P807S ENST00000528896 NM_014680.3 807 Cct/Tct 0 +KIAA0226 UCSF GRCh37 3 197401911 197401911 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 3 19 0 ENST00000296343.5:c.2897C>T p.Ala966Val p.A966V ENST00000296343 NM_014687.1 966 gCc/gTc 0 +KIAA0319L UCSF GRCh37 1 35972241 35972241 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 108 27 108 0 ENST00000325722.3:c.638G>A p.Gly213Asp p.G213D ENST00000325722 NM_024874.4 213 gGt/gAt 0 +KIAA0513 UCSF GRCh37 16 85121913 85121913 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 21 36 0 ENST00000258180.3:c.1218G>A p.Glu406= p.E406= ENST00000258180 NM_014732.2 406 gaG/gaA 0 +KIAA0564 UCSF GRCh37 13 42164844 42164844 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 32 58 0 ENST00000379310.3:c.5044G>A p.Ala1682Thr p.A1682T ENST00000379310 NM_015058.1 1682 Gcc/Acc 0 +KIAA0586 UCSF GRCh37 14 58965622 58965622 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 89 24 100 0 ENST00000354386.6:c.4271C>T p.Ser1424Phe p.S1424F ENST00000354386 NM_001244189.1 1424 tCt/tTt 0 +KIAA1033 UCSF GRCh37 12 105527557 105527557 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 67 120 0 ENST00000332180.5:c.1209G>A p.Gln403= p.Q403= ENST00000332180 NM_015275.1 403 caG/caA 0 +KIAA1191 UCSF GRCh37 5 175777694 175777694 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 28 33 0 ENST00000298569.4:c.381G>A p.Leu127= p.L127= ENST00000298569 NM_020444.3 127 ctG/ctA 0 +KIAA1239 UCSF GRCh37 4 37327621 37327621 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 30 91 0 ENST00000309447.5:c.215G>A p.Arg72Lys p.R72K ENST00000309447 NM_001144990.1 72 aGa/aAa 0 +KIAA1244 UCSF GRCh37 6 138655542 138655542 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 30 35 0 ENST00000251691.4:c.5559G>A p.Gln1853= p.Q1853= ENST00000251691 NM_020340.4 1853 caG/caA 0 +KIAA1539 UCSF GRCh37 9 35107943 35107943 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 5 27 0 ENST00000322813.5:c.329G>A p.Gly110Glu p.G110E ENST00000322813 NM_025182.2 110 gGa/gAa 0 +KIAA1715 UCSF GRCh37 2 176804319 176804319 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 26 70 0 ENST00000272748.4:c.773G>A p.Arg258Lys p.R258K ENST00000272748 NM_030650.1 258 aGa/aAa 0 +KIAA1751 UCSF GRCh37 1 1887143 1887143 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 10 80 0 ENST00000493964.1:c.12G>A p.Glu4= p.E4= ENST00000493964 4 gaG/gaA 0 +KIAA1755 UCSF GRCh37 20 36867969 36867969 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 13 37 0 ENST00000279024.4:c.1708G>A p.Gly570Ser p.G570S ENST00000279024 NM_001029864.1 570 Ggt/Agt 0 +KIAA1755 UCSF GRCh37 20 36870058 36870058 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 14 77 0 ENST00000279024.4:c.475G>A p.Gly159Arg p.G159R ENST00000279024 NM_001029864.1 159 Gga/Aga 0 +KIAA1958 UCSF GRCh37 9 115422322 115422322 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 8 23 0 ENST00000337530.6:c.2124G>A p.Arg708= p.R708= ENST00000337530 NM_001287038.1 708 agG/agA 0 +KIF13B UCSF GRCh37 8 28984764 28984764 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 63 132 0 ENST00000524189.1:c.3097G>A p.Val1033Ile p.V1033I ENST00000524189 NM_015254.3 1033 Gtc/Atc 0 +KIF18A UCSF GRCh37 11 28058011 28058011 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 104 12 101 0 ENST00000263181.6:c.2149C>T p.Pro717Ser p.P717S ENST00000263181 NM_031217.3 717 Ccg/Tcg 0 +KIF1C UCSF GRCh37 17 4925549 4925549 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 8 15 0 ENST00000320785.5:c.2173G>A p.Val725Ile p.V725I ENST00000320785 NM_006612.5 725 Gtt/Att 0 +KIF2C UCSF GRCh37 1 45223768 45223768 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 27 49 0 ENST00000372224.4:c.1180G>A p.Gly394Ser p.G394S ENST00000372224 NM_006845.3 394 Ggc/Agc 0 +KIF3C UCSF GRCh37 2 26204031 26204031 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 10 15 0 ENST00000264712.3:c.756G>A p.Arg252= p.R252= ENST00000264712 NM_002254.6 252 agG/agA 0 +KIF4A UCSF GRCh37 X 69561757 69561757 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 8 45 0 ENST00000374403.3:c.1242C>T p.Ala414= p.A414= ENST00000374403 NM_012310.4 414 gcC/gcT 0 +KLHDC2 UCSF GRCh37 14 50247481 50247481 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 25 101 0 ENST00000298307.5:c.944C>T p.Thr315Ile p.T315I ENST00000298307 NM_014315.2 315 aCc/aTc 0 +KLHL13 UCSF GRCh37 X 117053549 117053549 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 46 68 0 ENST00000262820.3:c.505G>A p.Glu169Lys p.E169K ENST00000262820 NM_033495.3 169 Gaa/Aaa 0 +KLHL25 UCSF GRCh37 15 86312642 86312642 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 5 21 0 ENST00000337975.5:c.400G>A p.Asp134Asn p.D134N ENST00000337975 NM_022480.3 134 Gat/Aat 0 +KLK7 UCSF GRCh37 19 51483713 51483713 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 6 10 18 0 ENST00000391807.1:c.252G>A p.Thr84= p.T84= ENST00000391807 NM_139277.2 84 acG/acA 0 +KLRAQ1 UCSF GRCh37 2 48718230 48718230 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 37 79 0 ENST00000294952.8:c.1520G>A p.Gly507Glu p.G507E ENST00000294952 NM_001135629.2 507 gGa/gAa 0 +KLRC4-KLRK1 UCSF GRCh37 12 10525748 10525748 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 36 66 0 ENST00000240618.6:c.616C>T p.Pro206Ser p.P206S ENST00000240618 NM_007360.3 206 Cca/Tca 0 +KRBA2 UCSF GRCh37 17 8273222 8273222 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 95 21 74 0 ENST00000331336.2:c.709C>T p.Gln237Ter p.Q237* ENST00000331336 NM_213597.2 237 Cag/Tag 0 +KREMEN1 UCSF GRCh37 22 29533386 29533386 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 10 45 0 ENST00000407188.1:c.682C>T p.Pro228Ser p.P228S ENST00000407188 228 Cct/Tct 0 +KRI1 UCSF GRCh37 19 10672368 10672368 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 12 70 0 ENST00000312962.6:c.481G>A p.Glu161Lys p.E161K ENST00000312962 NM_023008.3 161 Gag/Aag 0 +KRT31 UCSF GRCh37 17 39552765 39552765 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 13 33 0 ENST00000251645.2:c.495C>T p.Ile165= p.I165= ENST00000251645 NM_002277.2 165 atC/atT 0 +KRT34 UCSF GRCh37 17 39534360 39534360 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 10 33 0 ENST00000394001.1:c.1262G>A p.Gly421Asp p.G421D ENST00000394001 NM_021013.3 421 gGc/gAc 0 +KRT5 UCSF GRCh37 12 52909602 52909602 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 25 70 0 ENST00000252242.4:c.1454G>A p.Gly485Glu p.G485E ENST00000252242 NM_000424.3 485 gGa/gAa 0 +KRT6B UCSF GRCh37 12 52845458 52845458 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 33 73 0 ENST00000252252.3:c.405C>T p.Ile135= p.I135= ENST00000252252 NM_005555.3 135 atC/atT 0 +KRT85 UCSF GRCh37 12 52756677 52756677 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 28 46 0 ENST00000257901.3:c.1038C>T p.Ile346= p.I346= ENST00000257901 NM_002283.3 346 atC/atT 0 +KRTAP1-5 UCSF GRCh37 17 39183012 39183012 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 5 28 0 ENST00000361883.5:c.396C>T p.Pro132= p.P132= ENST00000361883 NM_031957.1 132 ccC/ccT 0 +KRTAP10-7 UCSF GRCh37 21 46021353 46021353 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 73 12 54 0 ENST00000380102.2:c.832C>T p.Pro278Ser p.P278S ENST00000380102 NM_198689.2 278 Cct/Tct 0 +KRTAP5-4 UCSF GRCh37 11 1642838 1642838 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 12 48 0 ENST00000399682.1:c.486G>A p.Lys162= p.K162= ENST00000399682 NM_001012709.1 162 aaG/aaA 0 +KRTAP6-3 UCSF GRCh37 21 31965042 31965042 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 9 22 0 ENST00000391624.1:c.257G>A p.Gly86Asp p.G86D ENST00000391624 NM_181605.3 86 gGc/gAc 0 +KSR1 UCSF GRCh37 17 25932612 25932612 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 3 11 0 ENST00000398988.3:c.1422G>A p.Glu474= p.E474= ENST00000398988 NM_014238.1 474 gaG/gaA 0 +LAMA1 UCSF GRCh37 18 6999530 6999530 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 7 23 0 ENST00000389658.3:c.4577G>A p.Gly1526Glu p.G1526E ENST00000389658 NM_005559.3 1526 gGg/gAg 0 +LAMA1 UCSF GRCh37 18 7034641 7034641 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 24 78 0 ENST00000389658.3:c.1888C>T p.Pro630Ser p.P630S ENST00000389658 NM_005559.3 630 Cct/Tct 0 +LAMA2 UCSF GRCh37 6 129636958 129636958 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 72 29 111 0 ENST00000421865.2:c.3787G>A p.Glu1263Lys p.E1263K ENST00000421865 NM_001079823.1 1263 Gaa/Aaa 0 +LAMA2 UCSF GRCh37 6 129581855 129581855 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 97 16 73 0 ENST00000421865.2:c.2097-1G>A p.X699_splice ENST00000421865 NM_001079823.1 0 +LAMB1 UCSF GRCh37 7 107621127 107621127 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 37 81 0 ENST00000222399.6:c.806G>A p.Gly269Glu p.G269E ENST00000222399 NM_002291.2 269 gGa/gAa 0 +LAMB1 UCSF GRCh37 7 107591753 107591753 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 9 21 0 ENST00000222399.6:c.3309C>T p.Cys1103= p.C1103= ENST00000222399 NM_002291.2 1103 tgC/tgT 0 +LAMC2 UCSF GRCh37 1 183184600 183184600 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 13 42 0 ENST00000264144.4:c.281C>T p.Ala94Val p.A94V ENST00000264144 NM_005562.2 94 gCt/gTt 0 +LANCL3 UCSF GRCh37 X 37515001 37515001 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 22 13 36 0 ENST00000378619.3:c.634T>C p.Tyr212His p.Y212H ENST00000378619 NM_001170331.1 212 Tat/Cat 0 +LARGE UCSF GRCh37 22 34157444 34157444 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 28 83 0 ENST00000354992.2:c.20G>A p.Gly7Glu p.G7E ENST00000354992 NM_004737.4 7 gGg/gAg 0 +LCAT UCSF GRCh37 16 67976808 67976808 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 9 39 0 ENST00000264005.5:c.383G>A p.Gly128Asp p.G128D ENST00000264005 NM_000229.1 128 gGc/gAc 0 +LCLAT1 UCSF GRCh37 2 30790968 30790968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 16 86 0 ENST00000309052.4:c.668G>A p.Gly223Glu p.G223E ENST00000309052 NM_182551.3 223 gGa/gAa 0 +LCN10 UCSF GRCh37 9 139635381 139635381 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 6 17 0 ENST00000474369.1:c.343G>A p.Ala115Thr p.A115T ENST00000474369 115 Gcc/Acc 0 +LCN2 UCSF GRCh37 9 130911921 130911921 + synonymous_variant Silent SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 59 14 23 0 ENST00000277480.2:c.117G>A p.Gln39= p.Q39= ENST00000277480 NM_005564.3 39 caG/caA 0 +LDHB UCSF GRCh37 12 21788613 21788613 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 59 21 63 0 ENST00000350669.1:c.868C>T p.Leu290= p.L290= ENST00000350669 NM_002300.6 290 Ctg/Ttg 0 +LEO1 UCSF GRCh37 15 52252231 52252231 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 36 69 0 ENST00000299601.5:c.1025G>A p.Gly342Glu p.G342E ENST00000299601 NM_138792.2 342 gGa/gAa 0 +LFNG UCSF GRCh37 7 2552829 2552829 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 15 77 0 ENST00000402506.1:c.86G>A p.Arg29Lys p.R29K ENST00000402506 NM_001166355.1 29 aGg/aAg 0 +LGALS12 UCSF GRCh37 11 63283765 63283765 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 8 14 0 ENST00000394618.3:c.911G>A p.Gly304Glu p.G304E ENST00000394618 NM_033101.3 304 gGg/gAg 0 +LGALS3 UCSF GRCh37 14 55604841 55604841 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 15 27 0 ENST00000254301.9:c.97G>A p.Ala33Thr p.A33T ENST00000254301 NM_002306.3 33 Gca/Aca 0 +LGI1 UCSF GRCh37 10 95557376 95557376 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 83 11 103 0 ENST00000371418.4:c.1490C>T p.Ser497Phe p.S497F ENST00000371418 NM_005097.2 497 tCc/tTc 0 +LGI3 UCSF GRCh37 8 22006117 22006117 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 6 9 0 ENST00000306317.2:c.1203C>T p.Ile401= p.I401= ENST00000306317 NM_139278.2 401 atC/atT 0 +LIG1 UCSF GRCh37 19 48665530 48665530 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 23 155 0 ENST00000263274.7:c.96G>A p.Glu32= p.E32= ENST00000263274 NM_000234.1 32 gaG/gaA 0 +LIMK2 UCSF GRCh37 22 31668561 31668561 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 9 48 0 ENST00000331728.4:c.1429G>A p.Val477Met p.V477M ENST00000331728 NM_005569.3 477 Gtg/Atg 0 +LIPE UCSF GRCh37 19 42911853 42911853 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 8 0 ENST00000244289.4:c.1747C>T p.Pro583Ser p.P583S ENST00000244289 NM_005357.2 583 Ccc/Tcc 0 +LLPH UCSF GRCh37 12 66517628 66517628 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 124 16 164 0 ENST00000266604.2:c.382G>A p.Ala128Thr p.A128T ENST00000266604 NM_032338.3 128 Gcc/Acc 0 +LNP1 UCSF GRCh37 3 100174747 100174747 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0011 P01_Rec Untested WXS Illumina HiSeq 47 12 116 0 ENST00000383693.3:c.514C>T p.Leu172= p.L172= ENST00000383693 NM_001085451.1 172 Ctg/Ttg 0 +LNX1 UCSF GRCh37 4 54424114 54424114 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 15 27 0 ENST00000263925.7:c.380+15676C>T *127* ENST00000263925 NM_001126328.2 0 +LOC100289561 UCSF GRCh37 7 102016320 102016320 + 5_prime_UTR_variant 5'UTR SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 47 72 0 ENST00000496391.1:c.-623G>A *208* ENST00000496391 0 +LOC200726 UCSF GRCh37 2 207509296 207509296 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 3 13 0 ENST00000543490.1:n.511C>T *171* ENST00000543490 0 +LOC554223 UCSF GRCh37 6 29759888 29759888 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 15 23 0 ENST00000320533.2:n.961G>A *321* ENST00000320533 0 +LPA UCSF GRCh37 6 160968838 160968838 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 86 11 89 0 ENST00000316300.5:c.5287G>A p.Ala1763Thr p.A1763T ENST00000316300 1763 Gca/Aca 0 +LPA UCSF GRCh37 6 161026196 161026196 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 95 151 0 ENST00000316300.5:c.2827G>A p.Gly943Arg p.G943R ENST00000316300 943 Gga/Aga 0 +LPCAT4 UCSF GRCh37 15 34657243 34657243 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 13 27 0 ENST00000314891.6:c.444C>T p.Ser148= p.S148= ENST00000314891 NM_153613.2 148 tcC/tcT 0 +LPHN2 UCSF GRCh37 1 82435041 82435041 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 73 57 111 0 ENST00000370717.2:c.2691C>T p.Phe897= p.F897= ENST00000370717 897 ttC/ttT 0 +LPHN3 UCSF GRCh37 4 62758677 62758677 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 17 56 0 ENST00000514591.1:c.1579+1G>A p.X527_splice ENST00000514591 0 +LPIN1 UCSF GRCh37 2 11922351 11922351 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 32 82 0 ENST00000256720.2:c.874G>A p.Glu292Lys p.E292K ENST00000256720 NM_145693.2 292 Gag/Aag 0 +LRBA UCSF GRCh37 4 151765869 151765869 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 30 77 0 ENST00000357115.3:c.4402G>A p.Gly1468Arg p.G1468R ENST00000357115 NM_006726.4 1468 Gga/Aga 0 +LRBA UCSF GRCh37 4 151818947 151818947 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 6 43 0 ENST00000357115.3:c.1948G>A p.Glu650Lys p.E650K ENST00000357115 NM_006726.4 650 Gaa/Aaa 0 +LRFN3 UCSF GRCh37 19 36431118 36431118 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0018 P01_Rec Untested WXS Illumina HiSeq 17 9 10 0 ENST00000246529.3:c.791C>T p.Ala264Val p.A264V ENST00000246529 NM_024509.1 264 gCg/gTg 0 +LRIF1 UCSF GRCh37 1 111494283 111494283 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 127 76 137 0 ENST00000369763.4:c.1223C>T p.Ser408Phe p.S408F ENST00000369763 NM_018372.3 408 tCc/tTc 0 +LRIG1 UCSF GRCh37 3 66434672 66434672 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 28 74 0 ENST00000273261.3:c.1814C>T p.Pro605Leu p.P605L ENST00000273261 NM_015541.2 605 cCc/cTc 0 +LRIG2 UCSF GRCh37 1 113655109 113655109 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 90 57 110 0 ENST00000361127.5:c.1807T>C p.Ser603Pro p.S603P ENST00000361127 NM_014813.1 603 Tct/Cct 0 +LRIT2 UCSF GRCh37 10 85982122 85982122 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 18 28 0 ENST00000372113.4:c.1207G>A p.Ala403Thr p.A403T ENST00000372113 NM_001017924.2 403 Gcc/Acc 0 +LRP2 UCSF GRCh37 2 170094605 170094605 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 19 39 0 ENST00000263816.3:c.4502G>A p.Arg1501Lys p.R1501K ENST00000263816 NM_004525.2 1501 aGa/aAa 0 +LRRC39 UCSF GRCh37 1 100620671 100620671 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 30 130 0 ENST00000342895.3:c.748C>T p.Leu250Phe p.L250F ENST00000342895 NM_001256387.1 250 Ctt/Ttt 0 +LRRC39 UCSF GRCh37 1 100620731 100620731 + missense_variant Missense_Mutation SNP G G C NOVEL P01_Rec Untested WXS Illumina HiSeq 33 9 74 1 ENST00000342895.3:c.688C>G p.Gln230Glu p.Q230E ENST00000342895 NM_001256387.1 230 Caa/Gaa 0 +LRRFIP1 UCSF GRCh37 2 238672239 238672240 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 0 ENST00000392000.4:c.1886dup p.Asn629LysfsTer12 p.N629Kfs*12 ENST00000392000 NM_001137552.1 628 gaa/gaAa 0 +LTF UCSF GRCh37 3 46492162 46492162 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 6 14 33 0 ENST00000231751.4:c.705G>A p.Glu235= p.E235= ENST00000231751 NM_002343.3 235 gaG/gaA 0 +LUZP1 UCSF GRCh37 1 23418565 23418565 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 101 63 109 0 ENST00000302291.4:c.2190C>T p.Leu730= p.L730= ENST00000302291 730 ctC/ctT 0 +LYG2 UCSF GRCh37 2 99870748 99870748 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 11 54 0 ENST00000333017.2:c.-25G>A p.X9_splice ENST00000333017 NM_175735.3 0 +LYPD3 UCSF GRCh37 19 43965763 43965763 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 3 17 0 ENST00000244333.3:c.781G>A p.Ala261Thr p.A261T ENST00000244333 NM_014400.2 261 Gcc/Acc 0 +LYST UCSF GRCh37 1 235933476 235933476 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 48 100 0 ENST00000389793.2:c.5906C>T p.Thr1969Ile p.T1969I ENST00000389793 NM_000081.3 1969 aCt/aTt 0 +MACC1 UCSF GRCh37 7 20199857 20199857 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 13 65 0 ENST00000332878.4:c.127C>T p.Pro43Ser p.P43S ENST00000332878 43 Cca/Tca 0 +MACC1 UCSF GRCh37 7 20193893 20193893 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 44 32 58 0 ENST00000332878.4:c.2269T>C p.Leu757= p.L757= ENST00000332878 757 Tta/Cta 0 +MADD UCSF GRCh37 11 47305933 47305933 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 13 50 0 ENST00000311027.5:c.1974C>T p.Asp658= p.D658= ENST00000311027 NM_003682.3 658 gaC/gaT 0 +MAGEC1 UCSF GRCh37 X 140994939 140994939 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 87 57 0 ENST00000285879.4:c.1749C>T p.Ser583= p.S583= ENST00000285879 NM_005462.4 583 agC/agT 0 +MAGI1 UCSF GRCh37 3 65416464 65416464 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 10 68 0 ENST00000402939.2:c.1456G>A p.Val486Met p.V486M ENST00000402939 NM_001033057.1 486 Gtg/Atg 0 +MAGI1 UCSF GRCh37 3 65456070 65456070 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 12 66 0 ENST00000402939.2:c.847C>T p.Pro283Ser p.P283S ENST00000402939 NM_001033057.1 283 Cct/Tct 0 +MAML1 UCSF GRCh37 5 179201692 179201692 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 12 33 0 ENST00000292599.3:c.2865G>A p.Leu955= p.L955= ENST00000292599 NM_014757.4 955 ctG/ctA 0 +MAML3 UCSF GRCh37 4 140812018 140812018 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 14 81 0 ENST00000509479.2:c.572G>A p.Arg191Gln p.R191Q ENST00000509479 NM_018717.4 191 cGa/cAa 0 +MAMLD1 UCSF GRCh37 X 149638978 149638978 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 38 29 0 ENST00000262858.5:c.1133G>A p.Ser378Asn p.S378N ENST00000262858 NM_005491.3 378 aGc/aAc 0 +MAN1B1 UCSF GRCh37 9 139995469 139995469 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 122 20 39 0 ENST00000371589.4:c.929C>T p.Ala310Val p.A310V ENST00000371589 NM_016219.4 310 gCc/gTc 0 +MAP1B UCSF GRCh37 5 71492237 71492237 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 17 34 0 ENST00000296755.7:c.3055G>A p.Glu1019Lys p.E1019K ENST00000296755 NM_005909.3 1019 Gag/Aag 0 +MAP1B UCSF GRCh37 5 71492669 71492669 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 46 0 ENST00000296755.7:c.3487A>G p.Thr1163Ala p.T1163A ENST00000296755 NM_005909.3 1163 Acc/Gcc 0 +MAP2K1 UCSF GRCh37 15 66735651 66735651 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 21 64 0 ENST00000307102.5:c.472G>A p.Ala158Thr p.A158T ENST00000307102 NM_002755.3 158 Gct/Act 0 +MAP2K5 UCSF GRCh37 15 67873162 67873162 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 10 107 0 ENST00000178640.5:c.322+1G>A p.X108_splice ENST00000178640 NM_145160.2 0 +MAP3K1 UCSF GRCh37 5 56178158 56178158 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 79 12 102 0 ENST00000399503.3:c.3131C>T p.Pro1044Leu p.P1044L ENST00000399503 NM_005921.1 1044 cCa/cTa 0 +MAP3K14 UCSF GRCh37 17 43364087 43364087 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 7 24 0 ENST00000344686.2:n.969C>T *323* ENST00000344686 0 +MAP3K9 UCSF GRCh37 14 71197444 71197444 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 11 31 0 ENST00000554752.2:c.2968G>A p.Glu990Lys p.E990K ENST00000554752 NM_001284230.1 990 Gag/Aag 0 +MAPK8IP3 UCSF GRCh37 16 1817179 1817179 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 6 18 0 ENST00000250894.4:c.3115C>T p.Leu1039= p.L1039= ENST00000250894 NM_015133.3 1039 Cta/Tta 0 +MARCH3 UCSF GRCh37 5 126214081 126214081 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 10 14 0 ENST00000308660.5:c.399G>A p.Leu133= p.L133= ENST00000308660 NM_178450.4 133 ctG/ctA 0 +MARK1 UCSF GRCh37 1 220805553 220805553 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 121 24 165 0 ENST00000366917.4:c.1020C>T p.Val340= p.V340= ENST00000366917 NM_001286124.1 340 gtC/gtT 0 +MASP1 UCSF GRCh37 3 186961306 186961306 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 7 73 0 ENST00000337774.5:c.1194G>A p.Gln398= p.Q398= ENST00000337774 NM_001879.5 398 caG/caA 0 +MAT1A UCSF GRCh37 10 82036304 82036304 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 42 46 0 ENST00000372213.3:c.596G>A p.Arg199His p.R199H ENST00000372213 NM_000429.2 199 cGc/cAc 0 +MBD2 UCSF GRCh37 18 51729304 51729304 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 129 17 92 0 ENST00000256429.3:c.702+2064C>T *234* ENST00000256429 NM_003927.4 0 +MCTS1 UCSF GRCh37 X 119742162 119742162 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 43 0 ENST00000371317.5:c.345C>T p.Gly115= p.G115= ENST00000371317 NM_014060.2 115 ggC/ggT 0 +MDGA1 UCSF GRCh37 6 37612308 37612308 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 7 21 0 ENST00000434837.3:c.2366C>T p.Thr789Ile p.T789I ENST00000434837 NM_153487.3 789 aCt/aTt 0 +MDM1 UCSF GRCh37 12 68724946 68724946 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 116 58 138 0 ENST00000303145.7:c.74C>T p.Ser25Phe p.S25F ENST00000303145 NM_017440.4 25 tCt/tTt 0 +MDN1 UCSF GRCh37 6 90353891 90353891 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 23 55 0 ENST00000369393.3:c.16624G>A p.Val5542Ile p.V5542I ENST00000369393 5542 Gta/Ata 0 +MECOM UCSF GRCh37 3 168834238 168834238 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 47 75 0 ENST00000468789.1:c.858G>A p.Arg286= p.R286= ENST00000468789 NM_001105078.3 286 agG/agA 0 +MED23 UCSF GRCh37 6 131944578 131944578 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 27 55 0 ENST00000368068.3:c.309C>T p.Asn103= p.N103= ENST00000368068 NM_004830.3 103 aaC/aaT 0 +MED6 UCSF GRCh37 14 71063384 71063384 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 14 49 0 ENST00000256379.5:c.218C>T p.Ala73Val p.A73V ENST00000256379 NM_005466.2 73 gCt/gTt 0 +MEF2D UCSF GRCh37 1 156453081 156453081 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 8 47 0 ENST00000348159.4:c.4G>A p.Gly2Arg p.G2R ENST00000348159 NM_005920.3 2 Ggg/Agg 0 +MEGF11 UCSF GRCh37 15 66206268 66206268 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 6 28 0 ENST00000409699.2:c.2517C>T p.Ser839= p.S839= ENST00000409699 839 agC/agT 0 +MEGF9 UCSF GRCh37 9 123370235 123370235 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 157 37 128 0 ENST00000373930.3:c.1141C>T p.Pro381Ser p.P381S ENST00000373930 NM_001080497.2 381 Ccg/Tcg 0 +METTL21D UCSF GRCh37 14 50583152 50583152 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 7 15 0 ENST00000395860.2:c.119G>A p.Cys40Tyr p.C40Y ENST00000395860 NM_024558.2 40 tGc/tAc 0 +METTL22 UCSF GRCh37 16 8729153 8729153 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 3 18 0 ENST00000381920.3:c.684G>A p.Arg228= p.R228= ENST00000381920 NM_024109.2 228 cgG/cgA 0 +MFGE8 UCSF GRCh37 15 89444857 89444857 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 5 23 0 ENST00000268150.8:c.795C>T p.Ser265= p.S265= ENST00000268150 NM_005928.2 265 tcC/tcT 0 +MFN1 UCSF GRCh37 3 179096384 179096384 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 6 37 0 ENST00000471841.1:c.1444C>T p.Pro482Ser p.P482S ENST00000471841 NM_033540.2 482 Cca/Tca 0 +MFSD11 UCSF GRCh37 17 74771222 74771222 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 20 73 0 ENST00000336509.4:c.1018G>A p.Gly340Arg p.G340R ENST00000336509 NM_001242533.1 340 Gga/Aga 0 +MFSD6L UCSF GRCh37 17 8700813 8700813 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 9 17 0 ENST00000329805.4:c.1626G>A p.Gln542= p.Q542= ENST00000329805 NM_152599.3 542 caG/caA 0 +MGAM UCSF GRCh37 7 141734145 141734145 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 9 50 0 ENST00000549489.2:c.1753C>T p.Leu585= p.L585= ENST00000549489 NM_004668.2 585 Ctg/Ttg 0 +MGAT5 UCSF GRCh37 2 135185983 135185983 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 16 46 0 ENST00000281923.2:c.1842G>A p.Gln614= p.Q614= ENST00000281923 NM_002410.4 614 caG/caA 0 +MGLL UCSF GRCh37 3 127441406 127441406 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 9 25 0 ENST00000398104.1:c.236G>A p.Gly79Asp p.G79D ENST00000398104 NM_001003794.2 79 gGc/gAc 0 +MICAL1 UCSF GRCh37 6 109770019 109770019 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 20 45 0 ENST00000358807.3:c.1580G>A p.Gly527Glu p.G527E ENST00000358807 NM_022765.3 527 gGa/gAa 0 +MICALL1 UCSF GRCh37 22 38318007 38318007 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 11 12 0 ENST00000215957.6:c.598C>T p.Pro200Ser p.P200S ENST00000215957 NM_033386.3 200 Cct/Tct 0 +MICB UCSF GRCh37 6 31473641 31473641 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 6 22 0 ENST00000252229.6:c.318G>A p.Gln106= p.Q106= ENST00000252229 NM_005931.3 106 caG/caA 0 +MICU1 UCSF GRCh37 10 74183121 74183121 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 100 65 107 0 ENST00000361114.5:c.942C>T p.Arg314= p.R314= ENST00000361114 NM_001195518.1 314 cgC/cgT 0 +MLH1 UCSF GRCh37 3 37090054 37090054 + missense_variant Missense_Mutation SNP C C T snp132_rs63750610 P01_Rec somatic WXS Sanger Illumina HiSeq 5 18 44 0 ENST00000231790.2:c.1943C>T p.Pro648Leu p.P648L ENST00000231790 NM_000249.3 648 cCc/cTc 0 +MLH3 UCSF GRCh37 14 75513566 75513566 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 156 21 198 0 ENST00000355774.2:c.2793G>A p.Glu931= p.E931= ENST00000355774 NM_001040108.1 931 gaG/gaA 0 +MLL UCSF GRCh37 11 118352750 118352750 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 27 48 0 ENST00000389506.5:c.3955G>A p.Val1319Ile p.V1319I ENST00000389506 1319 Gtt/Att 0 +MLL UCSF GRCh37 11 118366480 118366480 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 40 16 75 0 ENST00000389506.5:c.5420A>G p.Glu1807Gly p.E1807G ENST00000389506 1807 gAg/gGg 0 +MLL2 UCSF GRCh37 12 49436538 49436538 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 44 67 0 ENST00000301067.7:c.5768G>A p.Arg1923Lys p.R1923K ENST00000301067 NM_003482.3 1923 aGg/aAg 0 +MLL2 UCSF GRCh37 12 49448494 49448494 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 12 28 0 ENST00000301067.7:c.217G>A p.Glu73Lys p.E73K ENST00000301067 NM_003482.3 73 Gag/Aag 0 +MLL2 UCSF GRCh37 12 49440104 49440104 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 28 40 0 ENST00000301067.7:c.4522C>T p.Pro1508Ser p.P1508S ENST00000301067 NM_003482.3 1508 Cct/Tct 0 +MLL2 UCSF GRCh37 12 49433798 49433798 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 5 29 0 ENST00000301067.7:c.7755G>A p.Gly2585= p.G2585= ENST00000301067 NM_003482.3 2585 ggG/ggA 0 +MLL3 UCSF GRCh37 7 151874749 151874749 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 12 69 0 ENST00000262189.6:c.7789C>T p.Pro2597Ser p.P2597S ENST00000262189 NM_170606.2 2597 Cca/Tca 0 +MLL3 UCSF GRCh37 7 151874636 151874636 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 92 18 64 0 ENST00000262189.6:c.7902G>A p.Glu2634= p.E2634= ENST00000262189 NM_170606.2 2634 gaG/gaA 0 +MLL5 UCSF GRCh37 7 104745979 104745979 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 17 107 0 ENST00000257745.4:c.2290C>T p.Pro764Ser p.P764S ENST00000257745 NM_018682.3 764 Cct/Tct 0 +MLLT4 UCSF GRCh37 6 168352396 168352396 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 9 71 0 ENST00000447894.2:c.4341G>A p.Gln1447= p.Q1447= ENST00000447894 1447 caG/caA 0 +MLPH UCSF GRCh37 2 238419669 238419669 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 143 17 94 0 ENST00000264605.3:c.370C>T p.His124Tyr p.H124Y ENST00000264605 NM_024101.6 124 Cat/Tat 0 +MMP9 UCSF GRCh37 20 44640922 44640922 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 10 27 0 ENST00000372330.3:c.1144G>A p.Asp382Asn p.D382N ENST00000372330 NM_004994.2 382 Gac/Aac 0 +MOAP1 UCSF GRCh37 14 93650341 93650341 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 20 130 0 ENST00000298894.4:c.247C>T p.Pro83Ser p.P83S ENST00000298894 NM_022151.4 83 Ccg/Tcg 0 +MOAP1 UCSF GRCh37 14 93649577 93649577 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 29 66 0 ENST00000298894.4:c.1011G>A p.Glu337= p.E337= ENST00000298894 NM_022151.4 337 gaG/gaA 0 +MOB3A UCSF GRCh37 19 2078282 2078282 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 9 10 0 ENST00000357066.3:c.278G>A p.Gly93Glu p.G93E ENST00000357066 NM_130807.2 93 gGg/gAg 0 +MORC4 UCSF GRCh37 X 106229341 106229341 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 30 56 0 ENST00000355610.4:c.398G>A p.Gly133Glu p.G133E ENST00000355610 NM_001085354.2 133 gGa/gAa 0 +MOSPD1 UCSF GRCh37 X 134033430 134033430 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 8 44 0 ENST00000370783.3:c.34G>A p.Glu12Lys p.E12K ENST00000370783 NM_019556.1 12 Gaa/Aaa 0 +MOV10L1 UCSF GRCh37 22 50588095 50588095 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 3 15 0 ENST00000262794.5:c.2679G>A p.Glu893= p.E893= ENST00000262794 NM_018995.2 893 gaG/gaA 0 +MRPL10 UCSF GRCh37 17 45904022 45904022 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 3 37 0 ENST00000351111.2:c.513G>A p.Val171= p.V171= ENST00000351111 NM_145255.3 171 gtG/gtA 0 +MRPS17 UCSF GRCh37 7 56022783 56022783 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 49 76 0 ENST00000285298.4:c.305G>A p.Gly102Glu p.G102E ENST00000285298 NM_015969.2 102 gGa/gAa 0 +MRVI1 UCSF GRCh37 11 10602125 10602125 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 113 21 92 0 ENST00000423302.2:c.2372G>A p.Gly791Asp p.G791D ENST00000423302 NM_130385.3 791 gGt/gAt 0 +MSLN UCSF GRCh37 16 816698 816698 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 22 0 ENST00000382862.3:c.1285G>A p.Gly429Arg p.G429R ENST00000382862 NM_013404.4 429 Gga/Aga 0 +MSN UCSF GRCh37 X 64949352 64949352 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 12 40 0 ENST00000360270.5:c.245C>T p.Ala82Val p.A82V ENST00000360270 NM_002444.2 82 gCc/gTc 0 +MST1 UCSF GRCh37 3 49725201 49725201 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 5 15 31 0 ENST00000383728.3:c.18-100G>A *6* ENST00000383728 0 +MST1 UCSF GRCh37 3 49723144 49723144 + 3_prime_UTR_variant 3'UTR SNP C C T 1000g2010nov_all_0.040,snp132_rs9713630 P01_Rec Untested WXS Illumina HiSeq 17 7 25 1 ENST00000383728.3:c.*372G>A *124* ENST00000383728 0 +MSX1 UCSF GRCh37 4 4864447 4864447 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 27 37 0 ENST00000382723.4:c.489C>T p.Ala163= p.A163= ENST00000382723 NM_002448.3 163 gcC/gcT 0 +MTIF3 UCSF GRCh37 13 28014446 28014446 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 87 13 108 0 ENST00000381116.1:c.140C>T p.Ser47Phe p.S47F ENST00000381116 47 tCc/tTc 0 +MTMR14 UCSF GRCh37 3 9712828 9712828 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 23 54 0 ENST00000296003.4:c.651G>A p.Glu217= p.E217= ENST00000296003 NM_001077525.2 217 gaG/gaA 0 +MTNR1B UCSF GRCh37 11 92715267 92715267 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 39 72 0 ENST00000257068.2:c.878G>A p.Ser293Asn p.S293N ENST00000257068 NM_005959.3 293 aGc/aAc 0 +MTOR UCSF GRCh37 1 11184573 11184573 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 36 26 41 0 ENST00000361445.4:c.6644C>T p.Ser2215Phe p.S2215F ENST00000361445 NM_004958.3 2215 tCt/tTt 0 +MUC12 UCSF GRCh37 7 100646542 100646542 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 213 47 168 0 ENST00000379442.3:c.13127G>A p.Ser4376Asn p.S4376N ENST00000379442 4376 aGc/aAc 0 +MUC17 UCSF GRCh37 7 100676996 100676996 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 192 25 155 0 ENST00000306151.4:c.2299C>T p.Leu767Phe p.L767F ENST00000306151 NM_001040105.1 767 Ctt/Ttt 0 +MUC17 UCSF GRCh37 7 100684346 100684346 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 129 75 155 0 ENST00000306151.4:c.9649C>T p.Pro3217Ser p.P3217S ENST00000306151 NM_001040105.1 3217 Cct/Tct 0 +MUC2 UCSF GRCh37 11 1092260 1092260 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 7 52 0 ENST00000441003.2:c.4079C>T p.Ser1360Phe p.S1360F ENST00000441003 NM_002457.2 1360 tCt/tTt 0 +MUC21 UCSF GRCh37 6 30954428 30954428 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 153 17 71 0 ENST00000376296.3:c.476C>T p.Ser159Phe p.S159F ENST00000376296 NM_001010909.2 159 tCc/tTc 0 +MUC21 UCSF GRCh37 6 30954650 30954650 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 139 22 83 0 ENST00000376296.3:c.698C>T p.Thr233Ile p.T233I ENST00000376296 NM_001010909.2 233 aCc/aTc 0 +MUC4 UCSF GRCh37 3 195513478 195513478 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 206 88 326 0 ENST00000463781.3:c.4973C>T p.Ser1658Phe p.S1658F ENST00000463781 NM_018406.6 1658 tCc/tTc 0 +MYBL1 UCSF GRCh37 8 67484738 67484739 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 0 ENST00000522677.3:c.1707dup p.Tyr570IlefsTer5 p.Y570Ifs*5 ENST00000522677 NM_001080416.2 569 aaa/aaAa 0 +MYBL2 UCSF GRCh37 20 42338616 42338616 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 107 25 95 0 ENST00000217026.4:c.1519G>A p.Asp507Asn p.D507N ENST00000217026 NM_002466.3 507 Gat/Aat 0 +MYBPHL UCSF GRCh37 1 109839724 109839724 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 20 60 0 ENST00000357155.1:c.518G>A p.Gly173Glu p.G173E ENST00000357155 NM_001265613.1 173 gGg/gAg 0 +MYCBP2 UCSF GRCh37 13 77642966 77642966 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 12 65 0 ENST00000357337.6:c.11791G>A p.Val3931Met p.V3931M ENST00000357337 3931 Gtg/Atg 0 +MYH10 UCSF GRCh37 17 8416890 8416890 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 34 38 0 ENST00000269243.4:c.2618G>A p.Gly873Glu p.G873E ENST00000269243 NM_005964.3 873 gGa/gAa 0 +MYH11 UCSF GRCh37 16 15835500 15835500 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 65 38 62 0 ENST00000300036.5:c.2679G>A p.Gln893= p.Q893= ENST00000300036 NM_002474.2 893 caG/caA 0 +MYH13 UCSF GRCh37 17 10206579 10206579 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 84 46 69 0 ENST00000252172.4:c.5601G>A p.Arg1867= p.R1867= ENST00000252172 NM_003802.2 1867 agG/agA 0 +MYH13 UCSF GRCh37 17 10267644 10267644 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 15 120 0 ENST00000252172.4:c.204G>A p.Arg68= p.R68= ENST00000252172 NM_003802.2 68 cgG/cgA 0 +MYH4 UCSF GRCh37 17 10363607 10363607 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 55 46 64 0 ENST00000255381.2:c.1179G>A p.Leu393= p.L393= ENST00000255381 NM_017533.2 393 ctG/ctA 0 +MYH6 UCSF GRCh37 14 23862195 23862195 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 11 32 0 ENST00000356287.3:c.3177C>T p.Gly1059= p.G1059= ENST00000356287 1059 ggC/ggT 0 +MYH7 UCSF GRCh37 14 23884352 23884352 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 29 41 0 ENST00000355349.3:c.5411C>T p.Ala1804Val p.A1804V ENST00000355349 NM_000257.2 1804 gCc/gTc 0 +MYH8 UCSF GRCh37 17 10305018 10305018 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 115 74 146 0 ENST00000403437.2:c.2773G>A p.Val925Met p.V925M ENST00000403437 NM_002472.2 925 Gtg/Atg 0 +MYL3 UCSF GRCh37 3 46904778 46904778 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 4 46 0 ENST00000292327.4:c.103G>A p.Val35Ile p.V35I ENST00000292327 NM_000258.2 35 Gtc/Atc 0 +MYLK UCSF GRCh37 3 123419528 123419528 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 26 10 64 1 ENST00000360304.3:c.2787G>A p.Leu929= p.L929= ENST00000360304 NM_053025.3 929 ctG/ctA 0 +MYO10 UCSF GRCh37 5 16701512 16701512 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 16 24 0 ENST00000513610.1:c.2992G>A p.Glu998Lys p.E998K ENST00000513610 NM_012334.2 998 Gaa/Aaa 0 +MYO10 UCSF GRCh37 5 16701948 16701948 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 12 54 0 ENST00000513610.1:c.2557-1G>A p.X853_splice ENST00000513610 NM_012334.2 0 +MYO15A UCSF GRCh37 17 18047868 18047868 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 17 0 ENST00000205890.5:c.6235G>A p.Ala2079Thr p.A2079T ENST00000205890 NM_016239.3 2079 Gcc/Acc 0 +MYO16 UCSF GRCh37 13 109365014 109365014 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 8 43 0 ENST00000356711.2:c.232C>T p.Arg78Trp p.R78W ENST00000356711 NM_015011.1 78 Cgg/Tgg 0 +MYO1E UCSF GRCh37 15 59445946 59445946 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 36 39 0 ENST00000288235.4:c.2923C>T p.Pro975Ser p.P975S ENST00000288235 NM_004998.3 975 Ccc/Tcc 0 +MYO3A UCSF GRCh37 10 26305789 26305789 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 35 88 0 ENST00000265944.5:c.549C>T p.Asn183= p.N183= ENST00000265944 NM_017433.4 183 aaC/aaT 0 +MYO3B UCSF GRCh37 2 171262121 171262121 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 13 55 0 ENST00000408978.4:c.2498G>A p.Gly833Asp p.G833D ENST00000408978 NM_138995.4 833 gGc/gAc 0 +MYO3B UCSF GRCh37 2 171238526 171238526 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 94 15 97 0 ENST00000408978.4:c.972G>A p.Arg324= p.R324= ENST00000408978 NM_138995.4 324 agG/agA 0 +MYO7B UCSF GRCh37 2 128393887 128393887 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 10 14 0 ENST00000409816.2:c.6033C>T p.Phe2011= p.F2011= ENST00000409816 2011 ttC/ttT 0 +MYOCD UCSF GRCh37 17 12666467 12666467 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 41 42 77 0 ENST00000343344.4:c.2323A>G p.Thr775Ala p.T775A ENST00000343344 775 Act/Gct 0 +MYOCD UCSF GRCh37 17 12620673 12620673 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 22 58 0 ENST00000343344.4:c.188C>T p.Ser63Phe p.S63F ENST00000343344 63 tCc/tTc 0 +MYOF UCSF GRCh37 10 95111245 95111245 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 21 73 0 ENST00000359263.4:c.3747C>T p.Leu1249= p.L1249= ENST00000359263 NM_013451.3 1249 ctC/ctT 0 +MYOM1 UCSF GRCh37 18 3151764 3151764 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 60 87 0 ENST00000356443.4:c.1771G>A p.Gly591Arg p.G591R ENST00000356443 NM_019856.1 591 Gga/Aga 0 +MYOM1 UCSF GRCh37 18 3173967 3173967 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 20 76 0 ENST00000356443.4:c.1143C>T p.Phe381= p.F381= ENST00000356443 NM_019856.1 381 ttC/ttT 0 +MYPN UCSF GRCh37 10 69959267 69959267 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 17 59 0 ENST00000358913.5:c.3428C>T p.Thr1143Ile p.T1143I ENST00000358913 NM_032578.3 1143 aCc/aTc 0 +MYPN UCSF GRCh37 10 69881321 69881321 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 21 47 0 ENST00000358913.5:c.126C>T p.Cys42= p.C42= ENST00000358913 NM_032578.3 42 tgC/tgT 0 +MYRIP UCSF GRCh37 3 40208666 40208666 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 4 26 24 0 ENST00000302541.6:c.665C>T p.Ala222Val p.A222V ENST00000302541 NM_015460.2 222 gCc/gTc 0 +NAALADL1 UCSF GRCh37 11 64821987 64821987 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 9 19 0 ENST00000358658.3:c.827C>T p.Ser276Phe p.S276F ENST00000358658 NM_005468.2 276 tCc/tTc 0 +NACA UCSF GRCh37 12 57114689 57114689 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 36 77 0 ENST00000356769.3:c.70+3547G>A *24* ENST00000356769 NM_001113202.1 0 +NAE1 UCSF GRCh37 16 66850916 66850916 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 17 94 0 ENST00000290810.3:c.700C>T p.Pro234Ser p.P234S ENST00000290810 234 Cct/Tct 0 +NAIF1 UCSF GRCh37 9 130829281 130829281 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 10 38 0 ENST00000373078.4:c.100C>T p.His34Tyr p.H34Y ENST00000373078 NM_197956.3 34 Cac/Tac 0 +NALCN UCSF GRCh37 13 101721137 101721137 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 12 51 0 ENST00000251127.6:c.4240G>A p.Ala1414Thr p.A1414T ENST00000251127 NM_052867.2 1414 Gca/Aca 0 +NAV1 UCSF GRCh37 1 201682021 201682021 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 20 43 0 ENST00000367296.4:c.834C>T p.Ser278= p.S278= ENST00000367296 NM_020443.4 278 agC/agT 0 +NAV3 UCSF GRCh37 12 78401021 78401021 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 11 65 0 ENST00000397909.2:c.1703C>T p.Pro568Leu p.P568L ENST00000397909 NM_001024383.1 568 cCt/cTt 0 +NBEAL2 UCSF GRCh37 3 47043734 47043734 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 7 9 30 0 ENST00000450053.3:c.5107G>A p.Ala1703Thr p.A1703T ENST00000450053 NM_015175.2 1703 Gct/Act 0 +NBPF3 UCSF GRCh37 1 21806654 21806654 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 97 46 107 0 ENST00000318249.5:c.1319C>T p.Pro440Leu p.P440L ENST00000318249 NM_032264.4 440 cCc/cTc 0 +NBPF3 UCSF GRCh37 1 21805842 21805842 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 142 22 131 0 ENST00000318249.5:c.1157G>A p.Arg386Lys p.R386K ENST00000318249 NM_032264.4 386 aGa/aAa 0 +NCAPG UCSF GRCh37 4 17844947 17844947 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 33 101 0 ENST00000251496.2:c.2947G>A p.Glu983Lys p.E983K ENST00000251496 NM_022346.4 983 Gaa/Aaa 0 +NCKAP1L UCSF GRCh37 12 54917237 54917237 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 97 21 107 0 ENST00000293373.6:c.1938G>A p.Lys646= p.K646= ENST00000293373 NM_005337.4 646 aaG/aaA 0 +NCKAP5 UCSF GRCh37 2 133540233 133540233 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 11 31 0 ENST00000409261.1:c.4151G>A p.Gly1384Glu p.G1384E ENST00000409261 NM_207363.2 1384 gGa/gAa 0 +NCOA3 UCSF GRCh37 20 46279918 46279918 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.00197 P01_Rec Untested WXS Illumina HiSeq 35 7 48 0 ENST00000371998.3:c.3844C>T p.Pro1282Ser p.P1282S ENST00000371998 1282 Cca/Tca 0 +NCOR1 UCSF GRCh37 17 16022800 16022800 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 93 33 105 0 ENST00000268712.3:c.1853-1G>A p.X618_splice ENST00000268712 NM_006311.3 0 +NCSTN UCSF GRCh37 1 160321500 160321500 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 131 21 116 0 ENST00000294785.5:c.748C>T p.Pro250Ser p.P250S ENST00000294785 NM_015331.2 250 Ccc/Tcc 0 +NDST1 UCSF GRCh37 5 149907410 149907410 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 11 14 0 ENST00000261797.6:c.558C>T p.Pro186= p.P186= ENST00000261797 NM_001543.4 186 ccC/ccT 0 +NDST3 UCSF GRCh37 4 119059216 119059216 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 14 59 0 ENST00000296499.5:c.1232G>A p.Gly411Asp p.G411D ENST00000296499 NM_004784.2 411 gGc/gAc 0 +NDUFS1 UCSF GRCh37 2 207014633 207014633 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 26 63 0 ENST00000233190.6:c.170G>A p.Gly57Asp p.G57D ENST00000233190 NM_005006.6 57 gGc/gAc 0 +NEB UCSF GRCh37 2 152468732 152468732 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 113 20 119 0 ENST00000172853.10:c.11044C>T p.Leu3682= p.L3682= ENST00000172853 3682 Cta/Tta 0 +NECAB1 UCSF GRCh37 8 91937778 91937778 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 35 73 0 ENST00000417640.2:c.510G>A p.Lys170= p.K170= ENST00000417640 NM_022351.4 170 aaG/aaA 0 +NEDD4 UCSF GRCh37 15 56139232 56139232 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 12 79 0 ENST00000508342.1:c.2800G>A p.Ala934Thr p.A934T ENST00000508342 NM_001284338.1 934 Gca/Aca 0 +NEDD9 UCSF GRCh37 6 11191145 11191145 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 8 39 0 ENST00000379446.5:c.957C>T p.Val319= p.V319= ENST00000379446 NM_001271033.1 319 gtC/gtT 0 +NEK3 UCSF GRCh37 13 52715162 52715162 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 14 50 0 ENST00000400357.2:c.876+2889C>T *292* ENST00000400357 0 +NEK9 UCSF GRCh37 14 75558142 75558142 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 23 0 ENST00000238616.5:c.2273G>A p.Gly758Asp p.G758D ENST00000238616 NM_033116.4 758 gGc/gAc 0 +NELF UCSF GRCh37 9 140346820 140346820 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 104 22 47 0 ENST00000371475.3:c.1233C>T p.Cys411= p.C411= ENST00000371475 NM_001130969.1 411 tgC/tgT 0 +NET1 UCSF GRCh37 10 5494459 5494459 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 10 28 0 ENST00000355029.4:c.502C>T p.Leu168Phe p.L168F ENST00000355029 NM_001047160.2 168 Ctc/Ttc 0 +NEU1 UCSF GRCh37 6 31827515 31827515 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 14 64 0 ENST00000375631.4:c.1229G>A p.Ser410Asn p.S410N ENST00000375631 NM_000434.3 410 aGt/aAt 0 +NEURL2 UCSF GRCh37 20 44518890 44518890 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 9 11 0 ENST00000372518.4:c.741C>T p.Gly247= p.G247= ENST00000372518 NM_001278535.1 247 ggC/ggT 0 +NEUROG3 UCSF GRCh37 10 71332566 71332566 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 6 10 0 ENST00000242462.4:c.234C>T p.Ser78= p.S78= ENST00000242462 NM_020999.3 78 agC/agT 0 +NF1 UCSF GRCh37 17 29553505 29553505 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 34 22 47 0 ENST00000358273.4:c.2054C>T p.Thr685Ile p.T685I ENST00000358273 NM_001042492.2 685 aCc/aTc 0 +NFASC UCSF GRCh37 1 204970336 204970336 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 5 29 0 ENST00000339876.6:c.3058C>T p.Pro1020Ser p.P1020S ENST00000339876 NM_001005388.2 1020 Ccc/Tcc 0 +NFATC3 UCSF GRCh37 16 68224758 68224758 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 47 74 0 ENST00000346183.3:c.2186C>T p.Pro729Leu p.P729L ENST00000346183 NM_173165.2 729 cCt/cTt 0 +NFKBID UCSF GRCh37 19 36387847 36387847 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 11 30 0 ENST00000396901.1:c.120G>A p.Gln40= p.Q40= ENST00000396901 NM_139239.1 40 caG/caA 0 +NFKBIE UCSF GRCh37 6 44230365 44230365 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 9 22 0 ENST00000275015.5:c.817G>A p.Ala273Thr p.A273T ENST00000275015 NM_004556.2 273 Gcg/Acg 0 +NHS UCSF GRCh37 X 17744999 17744999 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 58 62 0 ENST00000380060.3:c.2710C>T p.Pro904Ser p.P904S ENST00000380060 NM_198270.2 904 Cct/Tct 0 +NHSL1 UCSF GRCh37 6 138752697 138752697 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 9 17 0 ENST00000427025.2:c.2797G>A p.Ala933Thr p.A933T ENST00000427025 NM_020464.1 933 Gct/Act 0 +NHSL1 UCSF GRCh37 6 138753049 138753049 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 18 24 0 ENST00000427025.2:c.2445G>A p.Gly815= p.G815= ENST00000427025 NM_020464.1 815 ggG/ggA 0 +NHSL1 UCSF GRCh37 6 138753691 138753691 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 107 14 88 0 ENST00000427025.2:c.1803G>A p.Gly601= p.G601= ENST00000427025 NM_020464.1 601 ggG/ggA 0 +NID1 UCSF GRCh37 1 236180524 236180524 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 10 74 0 ENST00000264187.6:c.2178C>T p.Ile726= p.I726= ENST00000264187 NM_002508.2 726 atC/atT 0 +NKTR UCSF GRCh37 3 42662979 42662979 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 7 70 0 ENST00000232978.8:c.345G>A p.Gly115= p.G115= ENST00000232978 NM_005385.3 115 ggG/ggA 0 +NLN UCSF GRCh37 5 65105515 65105515 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 29 85 0 ENST00000380985.5:c.1701G>A p.Arg567= p.R567= ENST00000380985 NM_020726.4 567 agG/agA 0 +NLRC3 UCSF GRCh37 16 3604266 3604266 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 4 16 0 ENST00000359128.5:c.2244C>T p.Ser748= p.S748= ENST00000359128 748 tcC/tcT 0 +NLRP14 UCSF GRCh37 11 7083698 7083698 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 44 119 0 ENST00000299481.4:c.2939C>T p.Ala980Val p.A980V ENST00000299481 NM_176822.3 980 gCt/gTt 0 +NLRP4 UCSF GRCh37 19 56382267 56382267 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 7 46 0 ENST00000301295.6:c.2429G>A p.Arg810His p.R810H ENST00000301295 NM_134444.4 810 cGc/cAc 0 +NMBR UCSF GRCh37 6 142409531 142409531 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 17 15 0 ENST00000258042.1:c.265G>A p.Asp89Asn p.D89N ENST00000258042 NM_002511.2 89 Gac/Aac 0 +NME1-NME2 UCSF GRCh37 17 49248858 49248858 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 39 59 0 ENST00000393193.2:c.697C>T p.His233Tyr p.H233Y ENST00000393193 233 Cat/Tat 0 +NME1-NME2 UCSF GRCh37 17 49248924 49248924 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 18 78 0 ENST00000514264.2:c.418G>A p.Val140Ile p.V140I ENST00000514264 NM_001018137.2 140 Gtt/Att 0 +NOB1 UCSF GRCh37 16 69783509 69783509 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 11 80 0 ENST00000268802.5:c.352C>T p.His118Tyr p.H118Y ENST00000268802 NM_014062.2 118 Cac/Tac 0 +NOL8 UCSF GRCh37 9 95077331 95077331 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 22 66 0 ENST00000442668.2:c.1576C>T p.Pro526Ser p.P526S ENST00000442668 NM_017948.5 526 Ccc/Tcc 0 +NOL9 UCSF GRCh37 1 6592067 6592067 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 12 80 0 ENST00000377705.5:c.1608C>T p.Pro536= p.P536= ENST00000377705 NM_024654.4 536 ccC/ccT 0 +NOMO2 UCSF GRCh37 16 18555043 18555043 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 15 141 0 ENST00000381474.3:c.631C>T p.Pro211Ser p.P211S ENST00000381474 NM_001004060.1 211 Ccc/Tcc 0 +NOS2 UCSF GRCh37 17 26107878 26107878 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 10 20 0 ENST00000313735.6:c.919C>T p.Leu307= p.L307= ENST00000313735 NM_000625.4 307 Ctg/Ttg 0 +NOTCH2 UCSF GRCh37 1 120478152 120478152 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 48 90 0 ENST00000256646.2:c.3598G>A p.Gly1200Ser p.G1200S ENST00000256646 NM_024408.3 1200 Ggc/Agc 0 +NPAS3 UCSF GRCh37 14 34269087 34269087 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 4 9 0 ENST00000356141.4:c.1574G>A p.Ser525Asn p.S525N ENST00000356141 525 aGc/aAc 0 +NPFF UCSF GRCh37 12 53900629 53900629 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 38 98 0 ENST00000267017.3:c.273C>T p.Pro91= p.P91= ENST00000267017 NM_003717.2 91 ccC/ccT 0 +NPHP1 UCSF GRCh37 2 110922642 110922642 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 75 12 84 0 ENST00000393272.3:c.715G>A p.Glu239Lys p.E239K ENST00000393272 NM_207181.2 239 Gaa/Aaa 0 +NPRL2 UCSF GRCh37 3 50386307 50386307 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 11 28 48 0 ENST00000232501.3:c.583C>T p.Gln195Ter p.Q195* ENST00000232501 NM_006545.4 195 Caa/Taa 0 +NR1H3 UCSF GRCh37 11 47282796 47282796 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 7 16 0 ENST00000441012.2:c.504C>T p.Val168= p.V168= ENST00000441012 NM_005693.3 168 gtC/gtT 0 +NRIP1 UCSF GRCh37 21 16337740 16337740 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 97 68 143 0 ENST00000318948.4:c.2774G>A p.Ser925Asn p.S925N ENST00000318948 NM_003489.3 925 aGt/aAt 0 +NRIP1 UCSF GRCh37 21 16340169 16340169 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 16 107 0 ENST00000318948.4:c.345G>A p.Leu115= p.L115= ENST00000318948 NM_003489.3 115 ttG/ttA 0 +NRIP2 UCSF GRCh37 12 2944109 2944109 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 6 16 0 ENST00000337508.4:c.41C>T p.Ser14Phe p.S14F ENST00000337508 NM_031474.2 14 tCc/tTc 0 +NRIP2 UCSF GRCh37 12 2937137 2937137 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 6 24 0 ENST00000337508.4:c.655C>T p.Leu219= p.L219= ENST00000337508 NM_031474.2 219 Cta/Tta 0 +NRP1 UCSF GRCh37 10 33486635 33486635 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 6 48 0 ENST00000265371.4:c.1867G>A p.Gly623Ser p.G623S ENST00000265371 623 Ggc/Agc 0 +NRXN1 UCSF GRCh37 2 50850507 50850507 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 55 141 0 ENST00000406316.2:c.1079G>A p.Gly360Glu p.G360E ENST00000406316 NM_004801.4 360 gGa/gAa 0 +NSUN6 UCSF GRCh37 10 18903531 18903531 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 43 0 ENST00000377304.4:c.433G>A p.Gly145Arg p.G145R ENST00000377304 NM_182543.2 145 Gga/Aga 0 +NT5C2 UCSF GRCh37 10 104849440 104849440 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 14 20 0 ENST00000343289.5:c.1675G>A p.Glu559Lys p.E559K ENST00000343289 NM_012229.4 559 Gag/Aag 0 +NTNG1 UCSF GRCh37 1 107979300 107979300 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 56 102 0 ENST00000370068.1:c.1269C>T p.Asn423= p.N423= ENST00000370068 423 aaC/aaT 0 +NUDT21 UCSF GRCh37 16 56485037 56485037 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 5 37 0 ENST00000300291.5:c.78G>A p.Gln26= p.Q26= ENST00000300291 NM_007006.2 26 caG/caA 0 +NUFIP1 UCSF GRCh37 13 45563287 45563287 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 14 16 0 ENST00000379161.4:c.285C>T p.Ala95= p.A95= ENST00000379161 NM_012345.2 95 gcC/gcT 0 +NUP133 UCSF GRCh37 1 229611477 229611477 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 9 62 0 ENST00000261396.3:c.1759G>A p.Ala587Thr p.A587T ENST00000261396 NM_018230.2 587 Gca/Aca 0 +NUP153 UCSF GRCh37 6 17632906 17632906 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 132 16 78 0 ENST00000262077.2:c.2634G>A p.Lys878= p.K878= ENST00000262077 NM_001278210.1 878 aaG/aaA 0 +NUP210 UCSF GRCh37 3 13363194 13363194 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 50 72 0 ENST00000254508.5:c.5057C>T p.Pro1686Leu p.P1686L ENST00000254508 NM_024923.3 1686 cCc/cTc 0 +NUP214 UCSF GRCh37 9 134074253 134074253 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 24 49 0 ENST00000359428.5:c.5372C>T p.Pro1791Leu p.P1791L ENST00000359428 NM_005085.3 1791 cCc/cTc 0 +NUP214 UCSF GRCh37 9 134038400 134038400 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 96 32 63 0 ENST00000359428.5:c.2563G>A p.Glu855Lys p.E855K ENST00000359428 NM_005085.3 855 Gag/Aag 0 +NUP214 UCSF GRCh37 9 134074061 134074061 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 9 37 0 ENST00000359428.5:c.5180G>A p.Gly1727Glu p.G1727E ENST00000359428 NM_005085.3 1727 gGg/gAg 0 +NUP98 UCSF GRCh37 11 3697537 3697537 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 4 14 25 0 ENST00000359171.4:c.*136C>T *46* ENST00000359171 0 +NUP98 UCSF GRCh37 11 3733811 3733811 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 40 68 0 ENST00000359171.4:c.2725C>T p.Pro909Ser p.P909S ENST00000359171 909 Cct/Tct 0 +NUPL1 UCSF GRCh37 13 25905536 25905536 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 28 43 0 ENST00000381736.3:c.1275G>A p.Leu425= p.L425= ENST00000381736 NM_014089.3 425 ttG/ttA 0 +NVL UCSF GRCh37 1 224468833 224468833 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 28 89 0 ENST00000281701.6:c.1954C>T p.Leu652= p.L652= ENST00000281701 NM_002533.3 652 Cta/Tta 0 +NYNRIN UCSF GRCh37 14 24878470 24878470 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 53 17 46 0 ENST00000382554.3:c.1470G>A p.Gln490= p.Q490= ENST00000382554 NM_025081.2 490 caG/caA 0 +OBSCN UCSF GRCh37 1 228451969 228451969 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 11 63 0 ENST00000422127.1:c.4738G>A p.Val1580Met p.V1580M ENST00000422127 NM_001098623.2 1580 Gtg/Atg 0 +OBSCN UCSF GRCh37 1 228509188 228509188 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 14 21 0 ENST00000422127.1:c.14646C>T p.Ala4882= p.A4882= ENST00000422127 NM_001098623.2 4882 gcC/gcT 0 +ODF2 UCSF GRCh37 9 131261283 131261283 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 29 40 0 ENST00000434106.3:c.2179G>A p.Glu727Lys p.E727K ENST00000434106 NM_153433.1 727 Gaa/Aaa 0 +OGDHL UCSF GRCh37 10 50952079 50952079 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 10 10 0 ENST00000374103.4:c.1822G>A p.Ala608Thr p.A608T ENST00000374103 NM_018245.2 608 Gcc/Acc 0 +OGFRL1 UCSF GRCh37 6 72006265 72006265 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 14 63 0 ENST00000370435.4:c.546+1G>A p.X182_splice ENST00000370435 NM_024576.3 0 +OLFML2A UCSF GRCh37 9 127563934 127563934 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 9 27 0 ENST00000373580.3:c.911C>T p.Ala304Val p.A304V ENST00000373580 NM_182487.2 304 gCg/gTg 0 +OLFML2A UCSF GRCh37 9 127570103 127570103 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 8 21 0 ENST00000373580.3:c.1212C>T p.Pro404= p.P404= ENST00000373580 NM_182487.2 404 ccC/ccT 0 +OLFML3 UCSF GRCh37 1 114523942 114523942 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 23 38 0 ENST00000320334.4:c.772C>T p.Pro258Ser p.P258S ENST00000320334 NM_020190.2 258 Cca/Tca 0 +OPCML UCSF GRCh37 11 132306126 132306126 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 45 60 0 ENST00000331898.7:c.791C>T p.Ala264Val p.A264V ENST00000331898 NM_002545.3 264 gCc/gTc 0 +OPCML UCSF GRCh37 11 132527148 132527148 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 18 32 0 ENST00000331898.7:c.234G>A p.Gly78= p.G78= ENST00000331898 NM_002545.3 78 ggG/ggA 0 +OR10A3 UCSF GRCh37 11 7960335 7960335 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 37 63 0 ENST00000360759.3:c.733C>T p.Leu245Phe p.L245F ENST00000360759 NM_001003745.1 245 Ctc/Ttc 0 +OR10R2 UCSF GRCh37 1 158450020 158450020 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 151 34 119 0 ENST00000368152.1:c.353C>T p.Ala118Val p.A118V ENST00000368152 NM_001004472.1 118 gCt/gTt 0 +OR10S1 UCSF GRCh37 11 123848113 123848113 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 8 17 0 ENST00000531945.1:c.286G>A p.Ala96Thr p.A96T ENST00000531945 NM_001004474.1 96 Gca/Aca 0 +OR10S1 UCSF GRCh37 11 123848289 123848289 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 8 49 0 ENST00000531945.1:c.110C>T p.Ser37Phe p.S37F ENST00000531945 NM_001004474.1 37 tCt/tTt 0 +OR14J1 UCSF GRCh37 6 29274902 29274902 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 95 34 67 0 ENST00000377160.2:c.436G>A p.Val146Met p.V146M ENST00000377160 NM_030946.1 146 Gtg/Atg 0 +OR1A2 UCSF GRCh37 17 3101003 3101003 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 59 100 0 ENST00000381951.1:c.191C>T p.Ala64Val p.A64V ENST00000381951 NM_012352.1 64 gCc/gTc 0 +OR1C1 UCSF GRCh37 1 247921698 247921698 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 9 51 0 ENST00000408896.2:c.11G>A p.Arg4Lys p.R4K ENST00000408896 NM_012353.2 4 aGa/aAa 0 +OR2B3 UCSF GRCh37 6 29054960 29054960 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 21 54 0 ENST00000377173.2:c.66G>A p.Trp22Ter p.W22* ENST00000377173 NM_001005226.2 22 tgG/tgA 0 +OR2G2 UCSF GRCh37 1 247752365 247752365 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 27 51 0 ENST00000320065.1:c.704C>T p.Thr235Ile p.T235I ENST00000320065 NM_001001915.1 235 aCc/aTc 0 +OR3A2 UCSF GRCh37 17 3181566 3181566 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 20 50 0 ENST00000408891.2:c.664C>T p.Leu222Phe p.L222F ENST00000408891 NM_002551.3 222 Ctc/Ttc 0 +OR51B2 UCSF GRCh37 11 5345160 5345160 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 17 103 0 ENST00000328813.2:c.368C>T p.Ala123Val p.A123V ENST00000328813 NM_033180.4 123 gCc/gTc 0 +OR52B2 UCSF GRCh37 11 6190897 6190897 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 20 27 0 ENST00000530810.1:c.660C>T p.Tyr220= p.Y220= ENST00000530810 NM_001004052.1 220 taC/taT 0 +OR52W1 UCSF GRCh37 11 6220526 6220526 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 12 73 0 ENST00000311352.2:c.73C>T p.Leu25= p.L25= ENST00000311352 NM_001005178.1 25 Cta/Tta 0 +OR5K4 UCSF GRCh37 3 98073030 98073030 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 72 130 0 ENST00000354924.2:c.333C>T p.Asp111= p.D111= ENST00000354924 NM_001005517.1 111 gaC/gaT 0 +OR5L2 UCSF GRCh37 11 55595315 55595315 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 35 83 0 ENST00000378397.1:c.621G>A p.Glu207= p.E207= ENST00000378397 NM_001004739.1 207 gaG/gaA 0 +OR6C3 UCSF GRCh37 12 55725859 55725859 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 66 129 0 ENST00000379667.1:c.375G>A p.Lys125= p.K125= ENST00000379667 NM_054104.1 125 aaG/aaA 0 +OR7C1 UCSF GRCh37 19 14910638 14910638 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P01_Rec Untested WXS Illumina HiSeq 10 0 ENST00000248073.2:c.311delT p.Phe104SerfsTer12 p.F104Sfs*12 ENST00000248073 NM_198944.1 104 tTc/tc 0 +OR8G1 UCSF GRCh37 11 124121243 124121243 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 100 14 95 0 ENST00000341493.2:c.776+45C>T *259* ENST00000341493 NM_001002905.1 0 +OSBPL6 UCSF GRCh37 2 179170939 179170939 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 62 53 71 1 ENST00000190611.4:c.28C>T p.Pro10Ser p.P10S ENST00000190611 NM_032523.3 10 Cct/Tct 0 +OSCAR UCSF GRCh37 19 54600250 54600250 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 3 24 0 ENST00000359649.4:c.284C>T p.Thr95Ile p.T95I ENST00000359649 NM_206818.1 95 aCt/aTt 0 +OSGEPL1 UCSF GRCh37 2 190618771 190618771 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 122 19 106 0 ENST00000264151.5:c.834C>T p.Ile278= p.I278= ENST00000264151 NM_022353.2 278 atC/atT 0 +OTOA UCSF GRCh37 16 21742223 21742223 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 9 50 0 ENST00000286149.4:c.2315G>A p.Gly772Glu p.G772E ENST00000286149 772 gGa/gAa 0 +OTUD4 UCSF GRCh37 4 146076591 146076591 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 6 32 129 0 ENST00000447906.2:c.845T>C p.Leu282Ser p.L282S ENST00000447906 282 tTa/tCa 0 +OVOL2 UCSF GRCh37 20 18005411 18005411 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 10 38 0 ENST00000278780.6:c.697G>A p.Val233Met p.V233M ENST00000278780 NM_021220.2 233 Gtg/Atg 0 +OXCT2 UCSF GRCh37 1 40236219 40236219 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 18 56 0 ENST00000327582.5:c.709G>A p.Ala237Thr p.A237T ENST00000327582 NM_022120.1 237 Gct/Act 0 +OXNAD1 UCSF GRCh37 3 16343361 16343361 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 86 29 66 0 ENST00000285083.5:c.661G>A p.Glu221Lys p.E221K ENST00000285083 NM_138381.3 221 Gaa/Aaa 0 +P2RY14 UCSF GRCh37 3 150931103 150931103 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 55 155 0 ENST00000309170.3:c.1002C>T p.Ser334= p.S334= ENST00000309170 NM_014879.3 334 agC/agT 0 +P2RY4 UCSF GRCh37 X 69478678 69478678 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 6 15 0 ENST00000374519.2:c.797C>T p.Thr266Ile p.T266I ENST00000374519 NM_002565.3 266 aCc/aTc 0 +PABPC1 UCSF GRCh37 8 101717192 101717192 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 17 95 0 ENST00000318607.5:c.1780C>T p.Leu594Phe p.L594F ENST00000318607 NM_002568.3 594 Ctt/Ttt 0 +PABPC3 UCSF GRCh37 13 25672036 25672036 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 61 100 0 ENST00000281589.3:c.1700C>T p.Ala567Val p.A567V ENST00000281589 NM_030979.2 567 gCc/gTc 0 +PACSIN1 UCSF GRCh37 6 34496435 34496435 + missense_variant Missense_Mutation SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 62 14 42 2 ENST00000244458.2:c.237C>G p.Ser79Arg p.S79R ENST00000244458 79 agC/agG 0 +PACSIN2 UCSF GRCh37 22 43289512 43289512 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 10 19 0 ENST00000263246.3:c.168G>A p.Ala56= p.A56= ENST00000263246 NM_001184970.1 56 gcG/gcA 0 +PADI3 UCSF GRCh37 1 17592190 17592190 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 24 35 0 ENST00000375460.3:c.383G>A p.Arg128Lys p.R128K ENST00000375460 NM_016233.2 128 aGg/aAg 0 +PADI4 UCSF GRCh37 1 17674544 17674544 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 4 17 0 ENST00000375448.4:c.1155+1G>A p.X385_splice ENST00000375448 NM_012387.2 0 +PADI6 UCSF GRCh37 1 17707598 17707598 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 7 18 0 ENST00000434762.2:n.542C>T *181* ENST00000434762 0 +PAIP1 UCSF GRCh37 5 43529973 43529973 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 26 109 0 ENST00000306846.3:c.1261G>A p.Glu421Lys p.E421K ENST00000306846 NM_006451.4 421 Gag/Aag 0 +PAN2 UCSF GRCh37 12 56726781 56726781 + missense_variant Missense_Mutation SNP A A T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 15 65 0 ENST00000425394.2:c.98T>A p.Leu33Gln p.L33Q ENST00000425394 NM_001127460.2 33 cTg/cAg 0 +PANK4 UCSF GRCh37 1 2452596 2452596 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 17 55 0 ENST00000378466.3:c.366G>A p.Ala122= p.A122= ENST00000378466 NM_018216.1 122 gcG/gcA 0 +PAPD7 UCSF GRCh37 5 6750520 6750520 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 8 36 0 ENST00000230859.6:c.1014C>T p.Pro338= p.P338= ENST00000230859 NM_001171805.1 338 ccC/ccT 0 +PAPOLA UCSF GRCh37 14 96986446 96986446 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 74 13 75 0 ENST00000216277.8:c.63C>T p.Gly21= p.G21= ENST00000216277 NM_032632.4 21 ggC/ggT 0 +PAPPA UCSF GRCh37 9 118950399 118950399 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 9 27 0 ENST00000328252.3:c.1382G>A p.Cys461Tyr p.C461Y ENST00000328252 NM_002581.3 461 tGc/tAc 0 +PAQR3 UCSF GRCh37 4 79856412 79856412 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 37 80 0 ENST00000511594.1:c.211G>A p.Val71Ile p.V71I ENST00000511594 71 Gta/Ata 0 +PARD3B UCSF GRCh37 2 206037097 206037097 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 14 37 0 ENST00000406610.2:c.1783C>T p.Pro595Ser p.P595S ENST00000406610 NM_205863.3 595 Cca/Tca 0 +PARM1 UCSF GRCh37 4 75938106 75938106 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 97 49 110 0 ENST00000307428.7:c.515C>T p.Ser172Phe p.S172F ENST00000307428 NM_015393.3 172 tCc/tTc 0 +PARS2 UCSF GRCh37 1 55223436 55223436 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 22 35 0 ENST00000371279.3:c.1399G>A p.Asp467Asn p.D467N ENST00000371279 NM_152268.3 467 Gat/Aat 0 +PBRM1 UCSF GRCh37 3 52588816 52588816 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 4 11 15 0 ENST00000296302.7:c.4533G>A p.Gln1511= p.Q1511= ENST00000296302 1511 caG/caA 0 +PCDH12 UCSF GRCh37 5 141334941 141334941 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 4 16 0 ENST00000231484.3:c.2476C>T p.Leu826= p.L826= ENST00000231484 NM_016580.3 826 Ctg/Ttg 0 +PCDH15 UCSF GRCh37 10 55581869 55581869 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 135 18 140 0 ENST00000320301.6:c.5617A>G p.Thr1873Ala p.T1873A ENST00000320301 NM_033056.3 1873 Aca/Gca 0 +PCDH15 UCSF GRCh37 10 55591215 55591215 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 47 85 0 ENST00000320301.6:c.4062C>T p.Ile1354= p.I1354= ENST00000320301 NM_033056.3 1354 atC/atT 0 +PCDH9 UCSF GRCh37 13 66879031 66879031 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 9 66 0 ENST00000377865.2:c.3470C>T p.Pro1157Leu p.P1157L ENST00000377865 1157 cCt/cTt 0 +PCDHA1 UCSF GRCh37 5 140167217 140167217 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 26 37 0 ENST00000504120.2:c.1342G>A p.Val448Met p.V448M ENST00000504120 NM_018900.2 448 Gtg/Atg 0 +PCDHA2 UCSF GRCh37 5 140176090 140176090 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 8 15 0 ENST00000526136.1:c.1541G>A p.Ser514Asn p.S514N ENST00000526136 NM_018905.2 514 aGc/aAc 0 +PCDHA3 UCSF GRCh37 5 140182041 140182041 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 33 76 0 ENST00000522353.2:c.1259C>T p.Ala420Val p.A420V ENST00000522353 NM_018906.2 420 gCc/gTc 0 +PCDHB12 UCSF GRCh37 5 140590444 140590444 + synonymous_variant Silent SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 19 4 17 1 ENST00000239450.2:c.1965C>G p.Thr655= p.T655= ENST00000239450 NM_018932.3 655 acC/acG 0 +PCDHB16 UCSF GRCh37 5 140564227 140564227 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 8 30 0 ENST00000361016.2:c.2093C>T p.Ser698Leu p.S698L ENST00000361016 NM_020957.1 698 tCg/tTg 0 +PCDHB3 UCSF GRCh37 5 140481391 140481391 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 28 64 0 ENST00000231130.2:c.1158G>A p.Glu386= p.E386= ENST00000231130 NM_018937.2 386 gaG/gaA 0 +PCDHB8 UCSF GRCh37 5 140559730 140559730 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 15 38 0 ENST00000239444.2:c.2115G>A p.Ser705= p.S705= ENST00000239444 NM_019120.3 705 tcG/tcA 0 +PCDHGA1 UCSF GRCh37 5 140710722 140710722 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 51 104 0 ENST00000517417.1:c.471G>A p.Gly157= p.G157= ENST00000517417 NM_018912.2 157 ggG/ggA 0 +PCDHGB1 UCSF GRCh37 5 140729899 140729899 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 8 25 0 ENST00000523390.1:c.72C>T p.Cys24= p.C24= ENST00000523390 NM_018922.2 24 tgC/tgT 0 +PCDHGB7 UCSF GRCh37 5 140798736 140798736 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 11 75 0 ENST00000398594.2:c.1310C>T p.Thr437Ile p.T437I ENST00000398594 NM_018927.3 437 aCc/aTc 0 +PCDHGC4 UCSF GRCh37 5 140866462 140866462 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 23 40 0 ENST00000306593.1:c.1722C>T p.Ser574= p.S574= ENST00000306593 NM_018928.2 574 tcC/tcT 0 +PCDHGC5 UCSF GRCh37 5 140868812 140868812 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 10 21 0 ENST00000252087.1:c.5G>A p.Gly2Glu p.G2E ENST00000252087 NM_018929.2 2 gGg/gAg 0 +PCK2 UCSF GRCh37 14 24568906 24568906 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 14 29 0 ENST00000216780.4:c.992C>T p.Ala331Val p.A331V ENST00000216780 NM_004563.2 331 gCt/gTt 0 +PCLO UCSF GRCh37 7 82579900 82579900 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 99 23 81 0 ENST00000333891.9:c.10004C>T p.Ala3335Val p.A3335V ENST00000333891 NM_033026.5 3335 gCa/gTa 0 +PCNT UCSF GRCh37 21 47766078 47766078 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 10 24 0 ENST00000359568.5:c.676C>T p.Leu226= p.L226= ENST00000359568 NM_006031.5 226 Ctg/Ttg 0 +PDCD11 UCSF GRCh37 10 105202186 105202186 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 23 38 0 ENST00000369797.3:c.4924G>A p.Ala1642Thr p.A1642T ENST00000369797 NM_014976.1 1642 Gct/Act 0 +PDCD6IP UCSF GRCh37 3 33877759 33877759 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 39 95 0 ENST00000307296.3:c.1057+1G>A p.X353_splice ENST00000307296 0 +PDE4A UCSF GRCh37 19 10577842 10577842 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 18 37 0 ENST00000380702.2:c.2140G>A p.Ala714Thr p.A714T ENST00000380702 714 Gcg/Acg 0 +PDE5A UCSF GRCh37 4 120463649 120463649 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 23 53 0 ENST00000354960.3:c.1537G>A p.Glu513Lys p.E513K ENST00000354960 NM_001083.3 513 Gag/Aag 0 +PDE8A UCSF GRCh37 15 85634350 85634350 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 24 43 0 ENST00000310298.4:c.790C>T p.Pro264Ser p.P264S ENST00000310298 264 Cct/Tct 0 +PDGFRL UCSF GRCh37 8 17491717 17491717 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 74 16 71 0 ENST00000251630.6:c.934C>T p.Gln312Ter p.Q312* ENST00000251630 312 Cag/Tag 0 +PDIA4 UCSF GRCh37 7 148703056 148703056 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 4 20 0 ENST00000286091.4:c.1221G>A p.Lys407= p.K407= ENST00000286091 NM_004911.4 407 aaG/aaA 0 +PDPK1 UCSF GRCh37 16 2607947 2607947 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 16 75 0 ENST00000342085.4:c.268G>A p.Glu90Lys p.E90K ENST00000342085 NM_002613.4 90 Gaa/Aaa 0 +PDPR UCSF GRCh37 16 70165289 70165289 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 34 161 0 ENST00000288050.4:c.814C>T p.Pro272Ser p.P272S ENST00000288050 NM_017990.3 272 Ccc/Tcc 0 +PDS5B UCSF GRCh37 13 33275510 33275510 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 86 44 123 0 ENST00000315596.10:c.1791C>T p.Phe597= p.F597= ENST00000315596 NM_015032.3 597 ttC/ttT 0 +PEG3 UCSF GRCh37 19 57326617 57326617 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 4 64 0 ENST00000326441.9:c.3193G>A p.Gly1065Ser p.G1065S ENST00000326441 NM_006210.2 1065 Ggc/Agc 0 +PELI2 UCSF GRCh37 14 56763632 56763632 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 22 65 0 ENST00000267460.4:c.1011G>A p.Met337Ile p.M337I ENST00000267460 NM_021255.2 337 atG/atA 0 +PER2 UCSF GRCh37 2 239161738 239161738 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 6 20 0 ENST00000254657.3:c.2926G>A p.Ala976Thr p.A976T ENST00000254657 NM_022817.2 976 Gcc/Acc 0 +PFAS UCSF GRCh37 17 8166462 8166462 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 11 54 0 ENST00000314666.6:c.1446G>A p.Gly482= p.G482= ENST00000314666 NM_012393.2 482 ggG/ggA 0 +PFAS UCSF GRCh37 17 8167880 8167880 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 3 14 0 ENST00000314666.6:c.2010G>A p.Arg670= p.R670= ENST00000314666 NM_012393.2 670 agG/agA 0 +PFKFB2 UCSF GRCh37 1 207252331 207252331 + downstream_gene_variant 3'Flank SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 6 27 0 ENST00000367080 NM_006212.2 0 +PGBD3 UCSF GRCh37 10 50723790 50723790 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 173 20 160 0 ENST00000374127.3:c.1371C>T p.Asn457= p.N457= ENST00000374127 NM_170753.3 457 aaC/aaT 0 +PGM1 UCSF GRCh37 1 64117389 64117389 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 8 35 0 ENST00000371084.3:c.1330G>A p.Asp444Asn p.D444N ENST00000371084 NM_002633.2 444 Gac/Aac 0 +PGR UCSF GRCh37 11 100999666 100999666 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 11 16 0 ENST00000325455.5:c.136C>T p.Pro46Ser p.P46S ENST00000325455 NM_001202474.3 46 Cct/Tct 0 +PHC2 UCSF GRCh37 1 33820166 33820166 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 7 16 0 ENST00000257118.5:c.1391C>T p.Pro464Leu p.P464L ENST00000257118 NM_198040.2 464 cCc/cTc 0 +PHF17 UCSF GRCh37 4 129778576 129778576 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 87 58 115 0 ENST00000226319.6:c.948C>T p.Ser316= p.S316= ENST00000226319 NM_199320.2 316 agC/agT 0 +PHF2 UCSF GRCh37 9 96425291 96425291 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 9 42 0 ENST00000359246.4:c.1801G>A p.Ala601Thr p.A601T ENST00000359246 NM_005392.3 601 Gcc/Acc 0 +PHF2 UCSF GRCh37 9 96439887 96439887 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 137 41 105 0 ENST00000359246.4:c.3220G>A p.Gly1074Ser p.G1074S ENST00000359246 NM_005392.3 1074 Ggc/Agc 0 +PHF2 UCSF GRCh37 9 96437996 96437996 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 7 22 0 ENST00000359246.4:c.2757G>A p.Arg919= p.R919= ENST00000359246 NM_005392.3 919 agG/agA 0 +PHF21A UCSF GRCh37 11 45991440 45991440 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 11 17 0 ENST00000418153.2:c.625C>T p.Pro209Ser p.P209S ENST00000418153 209 Cct/Tct 0 +PI4KA UCSF GRCh37 22 21107225 21107225 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 50 93 0 ENST00000255882.6:c.2953G>A p.Val985Met p.V985M ENST00000255882 NM_058004.3 985 Gtg/Atg 0 +PI4KA UCSF GRCh37 22 21104219 21104219 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 3 18 0 ENST00000255882.6:c.3217C>T p.Pro1073Ser p.P1073S ENST00000255882 NM_058004.3 1073 Cct/Tct 0 +PIAS1 UCSF GRCh37 15 68438994 68438994 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 40 121 0 ENST00000249636.6:c.784G>A p.Val262Ile p.V262I ENST00000249636 NM_016166.1 262 Gta/Ata 0 +PIBF1 UCSF GRCh37 13 73357725 73357725 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 106 16 100 0 ENST00000326291.6:c.118C>T p.Arg40Ter p.R40* ENST00000326291 NM_006346.2 40 Cga/Tga 0 +PIGM UCSF GRCh37 1 160000672 160000672 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 92 16 109 0 ENST00000368090.2:c.858G>A p.Trp286Ter p.W286* ENST00000368090 NM_145167.2 286 tgG/tgA 0 +PIGX UCSF GRCh37 3 196454922 196454922 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 23 136 0 ENST00000392391.3:c.447C>T p.His149= p.H149= ENST00000392391 149 caC/caT 0 +PILRA UCSF GRCh37 7 99997491 99997491 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 47 0 ENST00000198536.2:c.873C>T p.Ser291= p.S291= ENST00000198536 NM_013439.2 291 agC/agT 0 +PITPNM3 UCSF GRCh37 17 6387053 6387053 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 8 13 0 ENST00000262483.8:c.371C>T p.Ser124Phe p.S124F ENST00000262483 NM_031220.3 124 tCc/tTc 0 +PITPNM3 UCSF GRCh37 17 6381403 6381403 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 12 24 0 ENST00000262483.8:c.792G>A p.Gly264= p.G264= ENST00000262483 NM_031220.3 264 ggG/ggA 0 +PIWIL4 UCSF GRCh37 11 94340784 94340784 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 9 44 0 ENST00000299001.6:c.1818G>A p.Glu606= p.E606= ENST00000299001 NM_152431.2 606 gaG/gaA 0 +PKHD1L1 UCSF GRCh37 8 110457088 110457088 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 119 84 146 0 ENST00000378402.5:c.4990G>A p.Val1664Met p.V1664M ENST00000378402 NM_177531.4 1664 Gtg/Atg 0 +PKHD1L1 UCSF GRCh37 8 110447525 110447525 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 133 33 146 0 ENST00000378402.5:c.3447C>T p.Phe1149= p.F1149= ENST00000378402 NM_177531.4 1149 ttC/ttT 0 +PKP3 UCSF GRCh37 11 397590 397590 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 7 23 0 ENST00000331563.2:c.996C>T p.Asp332= p.D332= ENST00000331563 NM_007183.2 332 gaC/gaT 0 +PLA2G2A UCSF GRCh37 1 20304605 20304605 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 15 34 0 ENST00000375111.3:c.195C>T p.Val65= p.V65= ENST00000375111 NM_001161727.1 65 gtC/gtT 0 +PLA2G5 UCSF GRCh37 1 20417094 20417094 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 7 45 0 ENST00000375108.3:c.326C>T p.Ala109Val p.A109V ENST00000375108 NM_000929.2 109 gCc/gTc 0 +PLAC1 UCSF GRCh37 X 133700690 133700690 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 21 49 0 ENST00000359237.4:c.23G>A p.Gly8Glu p.G8E ENST00000359237 NM_021796.3 8 gGa/gAa 0 +PLAC8 UCSF GRCh37 4 84026056 84026056 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 27 83 0 ENST00000311507.4:c.236G>A p.Gly79Asp p.G79D ENST00000311507 NM_016619.2 79 gGc/gAc 0 +PLB1 UCSF GRCh37 2 28847925 28847925 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 23 45 0 ENST00000327757.5:c.3529G>A p.Asp1177Asn p.D1177N ENST00000327757 NM_153021.4 1177 Gac/Aac 0 +PLCB1 UCSF GRCh37 20 8626764 8626764 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 14 61 0 ENST00000338037.6:c.400G>A p.Val134Ile p.V134I ENST00000338037 NM_015192.3 134 Gtt/Att 0 +PLCD1 UCSF GRCh37 3 38049598 38049598 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 4 38 0 ENST00000334661.4:c.2092G>A p.Ala698Thr p.A698T ENST00000334661 NM_006225.3 698 Gcc/Acc 0 +PLCD4 UCSF GRCh37 2 219492808 219492808 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 24 44 0 ENST00000417849.1:c.829G>A p.Asp277Asn p.D277N ENST00000417849 277 Gat/Aat 0 +PLCE1 UCSF GRCh37 10 95892040 95892040 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 45 82 0 ENST00000260766.3:c.1316G>A p.Gly439Asp p.G439D ENST00000260766 NM_016341.3 439 gGt/gAt 0 +PLCL2 UCSF GRCh37 3 17051554 17051554 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 73 10 159 0 ENST00000418129.2:c.338C>T p.Ala113Val p.A113V ENST00000418129 NM_001144382.1 113 gCa/gTa 0 +PLD5 UCSF GRCh37 1 242253290 242253290 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 121 25 125 0 ENST00000442594.2:c.1201G>A p.Asp401Asn p.D401N ENST00000442594 NM_152666.2 401 Gac/Aac 0 +PLDN UCSF GRCh37 15 45898679 45898679 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 85 13 105 0 ENST00000220531.3:c.486G>A p.Lys162= p.K162= ENST00000220531 NM_012388.2 162 aaG/aaA 0 +PLEKHG5 UCSF GRCh37 1 6535115 6535115 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 79 17 51 0 ENST00000400915.3:c.462G>A p.Lys154= p.K154= ENST00000400915 NM_001042663.1 154 aaG/aaA 0 +PLIN4 UCSF GRCh37 19 4511488 4511488 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 89 61 116 0 ENST00000301286.3:c.2442C>T p.Thr814= p.T814= ENST00000301286 NM_001080400.1 814 acC/acT 0 +PLK1 UCSF GRCh37 16 23700000 23700000 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 9 32 0 ENST00000300093.4:c.1204G>A p.Asp402Asn p.D402N ENST00000300093 NM_005030.3 402 Gat/Aat 0 +PLK3 UCSF GRCh37 1 45270013 45270013 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 23 17 0 ENST00000372201.4:c.1345G>A p.Glu449Lys p.E449K ENST00000372201 NM_004073.2 449 Gaa/Aaa 0 +PLS3 UCSF GRCh37 X 114883769 114883769 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 10 29 1 ENST00000355899.3:c.1781G>A p.Arg594Lys p.R594K ENST00000355899 NM_005032.5 594 aGa/aAa 0 +PLXNA2 UCSF GRCh37 1 208218077 208218077 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 7 17 0 ENST00000367033.3:c.3650G>A p.Gly1217Asp p.G1217D ENST00000367033 NM_025179.3 1217 gGc/gAc 0 +PLXNA4 UCSF GRCh37 7 131883310 131883310 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 14 21 0 ENST00000321063.4:c.2672C>T p.Ala891Val p.A891V ENST00000321063 NM_020911.1 891 gCc/gTc 0 +PLXNA4 UCSF GRCh37 7 131888097 131888097 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 9 28 0 ENST00000321063.4:c.2380C>T p.Pro794Ser p.P794S ENST00000321063 NM_020911.1 794 Cca/Tca 0 +PLXNB3 UCSF GRCh37 X 153036320 153036320 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 3 12 0 ENST00000361971.5:c.2118G>A p.Arg706= p.R706= ENST00000361971 NM_005393.2 706 cgG/cgA 0 +PLXNC1 UCSF GRCh37 12 94697645 94697645 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 16 105 0 ENST00000258526.4:c.4500G>A p.Met1500Ile p.M1500I ENST00000258526 NM_005761.2 1500 atG/atA 0 +PNKD UCSF GRCh37 2 219209653 219209653 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 8 45 0 ENST00000273077.4:c.1107C>T p.Ala369= p.A369= ENST00000273077 NM_015488.4 369 gcC/gcT 0 +PNLDC1 UCSF GRCh37 6 160224997 160224997 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 21 102 0 ENST00000610273.1:c.216G>A p.Lys72= p.K72= ENST00000610273 NM_173516.2 72 aaG/aaA 0 +PNMA3 UCSF GRCh37 X 152225506 152225506 + missense_variant,NMD_transcript_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0025 P01_Rec Untested WXS Illumina HiSeq 7 24 24 0 ENST00000424805.1:c.94G>A p.Glu32Lys p.E32K ENST00000424805 32 Gag/Aag 0 +PNMA5 UCSF GRCh37 X 152159173 152159173 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 4 28 0 ENST00000361887.5:c.970C>T p.Leu324Phe p.L324F ENST00000361887 NM_052926.2 324 Ctc/Ttc 0 +POLE UCSF GRCh37 12 133253196 133253196 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 8 35 0 ENST00000320574.5:c.845C>T p.Pro282Leu p.P282L ENST00000320574 NM_006231.2 282 cCc/cTc 0 +POLE2 UCSF GRCh37 14 50130071 50130071 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 16 53 0 ENST00000216367.5:c.717C>T p.Ala239= p.A239= ENST00000216367 NM_002692.3 239 gcC/gcT 0 +POLR1A UCSF GRCh37 2 86258542 86258542 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 11 33 0 ENST00000263857.6:c.4489G>A p.Ala1497Thr p.A1497T ENST00000263857 1497 Gcc/Acc 0 +POLR1B UCSF GRCh37 2 113300155 113300155 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 13 22 0 ENST00000263331.5:c.84G>A p.Arg28= p.R28= ENST00000263331 NM_019014.4 28 cgG/cgA 0 +POLR2A UCSF GRCh37 17 7400674 7400674 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 4 24 0 ENST00000322644.6:c.820-1G>A p.X274_splice ENST00000322644 NM_000937.4 0 +POLR2E UCSF GRCh37 19 1093980 1093980 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 8 18 0 ENST00000586746.1:c.155G>A p.Arg52Gln p.R52Q ENST00000586746 NM_002695.3 52 cGg/cAg 0 +POMT2 UCSF GRCh37 14 77755164 77755164 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 22 57 0 ENST00000261534.4:c.1194C>T p.Asp398= p.D398= ENST00000261534 NM_013382.5 398 gaC/gaT 0 +POTEE UCSF GRCh37 2 132010673 132010673 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 119 25 224 0 ENST00000356920.5:c.1778+1G>A p.X593_splice ENST00000356920 NM_001083538.1 0 +POTEF UCSF GRCh37 2 130832864 130832864 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 24 88 0 ENST00000357462.5:c.2181C>T p.Pro727= p.P727= ENST00000357462 727 ccC/ccT 0 +PPFIA2 UCSF GRCh37 12 81734921 81734921 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 26 80 0 ENST00000549396.1:c.2329C>T p.Pro777Ser p.P777S ENST00000549396 NM_003625.3 777 Cct/Tct 0 +PPFIBP1 UCSF GRCh37 12 27844782 27844782 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 121 22 122 0 ENST00000318304.8:c.2804G>A p.Gly935Glu p.G935E ENST00000318304 NM_177444.2 935 gGa/gAa 0 +PPHLN1 UCSF GRCh37 12 42745695 42745695 + stop_gained Nonsense_Mutation SNP C C A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 9 38 0 ENST00000395568.2:c.81C>A p.Tyr27Ter p.Y27* ENST00000395568 NM_016488.6 27 taC/taA 0 +PPIL1 UCSF GRCh37 6 36839493 36839493 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 169 43 130 0 ENST00000373699.5:c.211+1G>A p.X71_splice ENST00000373699 NM_016059.4 0 +PPIP5K2 UCSF GRCh37 5 102526558 102526558 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 36 128 0 ENST00000358359.3:c.3368C>T p.Ser1123Phe p.S1123F ENST00000358359 NM_001281471.1 1123 tCc/tTc 0 +PPIP5K2 UCSF GRCh37 5 102526637 102526637 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 89 51 151 0 ENST00000358359.3:c.3447C>T p.Ser1149= p.S1149= ENST00000358359 NM_001281471.1 1149 tcC/tcT 0 +PPL UCSF GRCh37 16 4934721 4934721 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 105 67 135 0 ENST00000345988.2:c.3935G>A p.Arg1312Lys p.R1312K ENST00000345988 NM_002705.4 1312 aGg/aAg 0 +PPM1G UCSF GRCh37 2 27606392 27606392 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 12 43 0 ENST00000344034.4:c.1042G>A p.Asp348Asn p.D348N ENST00000344034 NM_177983.2 348 Gac/Aac 0 +PPM1H UCSF GRCh37 12 63114037 63114037 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 42 112 0 ENST00000228705.6:c.987G>A p.Glu329= p.E329= ENST00000228705 NM_020700.1 329 gaG/gaA 0 +PPP2R1B UCSF GRCh37 11 111608252 111608252 + downstream_gene_variant 3'Flank SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 6 25 0 ENST00000527614 NM_001177562.1 0 +PPP6R2 UCSF GRCh37 22 50876724 50876724 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 15 0 ENST00000216061.5:c.1961C>T p.Pro654Leu p.P654L ENST00000216061 654 cCc/cTc 0 +PPRC1 UCSF GRCh37 10 103899228 103899228 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 22 34 0 ENST00000278070.2:c.963C>T p.Thr321= p.T321= ENST00000278070 NM_015062.3 321 acC/acT 0 +PRB1 UCSF GRCh37 12 11506577 11506577 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 10 42 0 ENST00000500254.2:c.313+147C>T *105* ENST00000500254 NM_199353.2 0 +PRB4 UCSF GRCh37 12 11461462 11461462 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 172 22 157 0 ENST00000279575.1:c.455C>T p.Ser152Phe p.S152F ENST00000279575 NM_001261399.1 152 tCc/tTc 0 +PRCC UCSF GRCh37 1 156770198 156770198 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 22 50 0 ENST00000271526.4:c.1422C>T p.Thr474= p.T474= ENST00000271526 NM_005973.4 474 acC/acT 0 +PRDM10 UCSF GRCh37 11 129785651 129785651 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 6 46 0 ENST00000358825.5:c.2442G>A p.Glu814= p.E814= ENST00000358825 NM_020228.2 814 gaG/gaA 0 +PRDM15 UCSF GRCh37 21 43258144 43258144 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 36 47 0 ENST00000269844.3:c.1998C>T p.Val666= p.V666= ENST00000269844 NM_022115.3 666 gtC/gtT 0 +PRDM2 UCSF GRCh37 1 14106686 14106686 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 30 44 0 ENST00000235372.7:c.2396G>A p.Cys799Tyr p.C799Y ENST00000235372 NM_012231.4 799 tGc/tAc 0 +PRDM5 UCSF GRCh37 4 121742370 121742370 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 132 24 141 0 ENST00000264808.3:c.431G>A p.Gly144Glu p.G144E ENST00000264808 NM_018699.2 144 gGg/gAg 0 +PRDM6 UCSF GRCh37 5 122515955 122515955 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.003,1000g2011may_all_0.00696 P01_Rec Untested WXS Illumina HiSeq 44 5 39 0 ENST00000407847.4:c.1611C>T p.Ala537= p.A537= ENST00000407847 NM_001136239.1 537 gcC/gcT 0 +PRDM8 UCSF GRCh37 4 81122444 81122444 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 27 35 0 ENST00000339711.4:c.220G>A p.Val74Ile p.V74I ENST00000339711 NM_020226.3 74 Gta/Ata 0 +PREX2 UCSF GRCh37 8 68939559 68939559 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 11 92 1 ENST00000288368.4:c.543+1G>A p.X181_splice ENST00000288368 NM_024870.2 0 +PRICKLE2 UCSF GRCh37 3 64184506 64184506 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 12 69 0 ENST00000295902.6:c.98C>T p.Ala33Val p.A33V ENST00000295902 NM_198859.3 33 gCt/gTt 0 +PRKAB1 UCSF GRCh37 12 120114413 120114413 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 28 51 0 ENST00000229328.5:c.604G>A p.Ala202Thr p.A202T ENST00000229328 NM_006253.4 202 Gca/Aca 0 +PRKCD UCSF GRCh37 3 53222751 53222751 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 13 54 0 ENST00000330452.3:c.1431C>T p.Asp477= p.D477= ENST00000330452 NM_006254.3 477 gaC/gaT 0 +PRND UCSF GRCh37 20 4705476 4705476 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 8 20 0 ENST00000305817.2:c.279C>T p.Gly93= p.G93= ENST00000305817 NM_012409.2 93 ggC/ggT 0 +PROC UCSF GRCh37 2 128186326 128186326 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 9 29 0 ENST00000234071.3:c.1190C>T p.Ala397Val p.A397V ENST00000234071 NM_000312.3 397 gCc/gTc 0 +PROL1 UCSF GRCh37 4 71275779 71275779 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 7 62 0 ENST00000399575.2:c.734C>T p.Ala245Val p.A245V ENST00000399575 NM_021225.4 245 gCc/gTc 0 +PROP1 UCSF GRCh37 5 177421246 177421246 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 10 32 0 ENST00000308304.2:c.203C>T p.Ser68Phe p.S68F ENST00000308304 NM_006261.4 68 tCc/tTc 0 +PROX1 UCSF GRCh37 1 214170923 214170923 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 26 74 0 ENST00000261454.4:c.1045G>A p.Ala349Thr p.A349T ENST00000261454 349 Gct/Act 0 +PRPF38B UCSF GRCh37 1 109242410 109242410 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 34 111 0 ENST00000370025.4:c.1409G>A p.Arg470Gln p.R470Q ENST00000370025 NM_018061.2 470 cGa/cAa 0 +PRR14L UCSF GRCh37 22 32112452 32112452 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 133 26 154 0 ENST00000327423.6:c.1373C>T p.Ser458Phe p.S458F ENST00000327423 NM_173566.2 458 tCt/tTt 0 +PRR5L UCSF GRCh37 11 36422804 36422804 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 13 0 ENST00000378867.3:c.133C>T p.Leu45= p.L45= ENST00000378867 NM_024841.4 45 Ctg/Ttg 0 +PRRC2B UCSF GRCh37 9 134351008 134351008 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 9 27 0 ENST00000357304.4:c.3492G>A p.Arg1164= p.R1164= ENST00000357304 NM_013318.3 1164 agG/agA 0 +PRUNE2 UCSF GRCh37 9 79465386 79465386 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 8 62 0 ENST00000376718.3:c.337C>T p.Leu113= p.L113= ENST00000376718 NM_015225.2 113 Ctg/Ttg 0 +PSG6 UCSF GRCh37 19 43414818 43414818 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 139 79 157 0 ENST00000292125.2:c.620C>T p.Thr207Ile p.T207I ENST00000292125 NM_002782.4 207 aCa/aTa 0 +PSG7 UCSF GRCh37 19 43430146 43430146 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 98 80 150 0 ENST00000406070.2:c.1022T>C p.Phe341Ser p.F341S ENST00000406070 NM_002783.2 341 tTc/tCc 0 +PSMD1 UCSF GRCh37 2 231944942 231944942 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 8 45 0 ENST00000308696.6:c.1327C>T p.Leu443Phe p.L443F ENST00000308696 NM_002807.3 443 Ctc/Ttc 0 +PSMD13 UCSF GRCh37 11 248855 248855 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 32 45 0 ENST00000532097.1:c.648C>T p.Leu216= p.L216= ENST00000532097 NM_002817.3 216 ctC/ctT 0 +PSMD2 UCSF GRCh37 3 184017696 184017696 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 25 74 0 ENST00000310118.4:c.192+1G>A p.X64_splice ENST00000310118 NM_002808.4 0 +PSPC1 UCSF GRCh37 13 20346466 20346466 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 13 73 0 ENST00000338910.4:c.590G>A p.Gly197Glu p.G197E ENST00000338910 NM_001042414.2 197 gGa/gAa 0 +PSTPIP1 UCSF GRCh37 15 77323605 77323605 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 12 37 0 ENST00000558012.1:c.727G>A p.Val243Ile p.V243I ENST00000558012 NM_003978.3 243 Gtc/Atc 0 +PTEN UCSF GRCh37 10 89690824 89690824 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 25 57 0 ENST00000371953.3:c.231C>T p.Asp77= p.D77= ENST00000371953 NM_000314.4 77 gaC/gaT 0 +PTGER4 UCSF GRCh37 5 40692104 40692104 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 6 47 0 ENST00000302472.3:c.1091C>T p.Ser364Leu p.S364L ENST00000302472 NM_000958.2 364 tCa/tTa 0 +PTGS1 UCSF GRCh37 9 125143830 125143830 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 13 31 0 ENST00000362012.2:c.677G>A p.Gly226Glu p.G226E ENST00000362012 NM_000962.3 226 gGg/gAg 0 +PTK7 UCSF GRCh37 6 43109797 43109797 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 10 21 0 ENST00000230419.4:c.1897G>A p.Asp633Asn p.D633N ENST00000230419 NM_002821.4 633 Gac/Aac 0 +PTK7 UCSF GRCh37 6 43098292 43098292 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 33 8 9 0 ENST00000230419.4:c.705A>G p.Val235= p.V235= ENST00000230419 NM_002821.4 235 gtA/gtG 0 +PTPN13 UCSF GRCh37 4 87690936 87690936 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 22 66 0 ENST00000411767.2:c.4504G>A p.Val1502Ile p.V1502I ENST00000411767 1502 Gta/Ata 0 +PTPN13 UCSF GRCh37 4 87731108 87731108 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 53 85 0 ENST00000411767.2:c.7270G>A p.Val2424Ile p.V2424I ENST00000411767 2424 Gtt/Att 0 +PTPN14 UCSF GRCh37 1 214546053 214546053 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 29 79 0 ENST00000366956.5:c.3036+1G>A p.X1012_splice ENST00000366956 NM_005401.4 0 +PTPN18 UCSF GRCh37 2 131128349 131128349 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 5 28 0 ENST00000175756.5:c.828G>A p.Gln276= p.Q276= ENST00000175756 NM_014369.3 276 caG/caA 0 +PTPRD UCSF GRCh37 9 8524986 8524986 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 7 100 0 ENST00000356435.5:c.618G>A p.Glu206= p.E206= ENST00000356435 206 gaG/gaA 0 +PTPRH UCSF GRCh37 19 55708101 55708101 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 9 13 0 ENST00000376350.3:c.2046C>T p.Val682= p.V682= ENST00000376350 NM_002842.3 682 gtC/gtT 0 +PTPRJ UCSF GRCh37 11 48145317 48145317 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 33 60 0 ENST00000418331.2:c.769G>A p.Val257Ile p.V257I ENST00000418331 NM_002843.3 257 Gtc/Atc 0 +PTPRQ UCSF GRCh37 12 81064145 81064145 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 13 100 0 ENST00000266688.5:c.6464G>A p.Arg2155Gln p.R2155Q ENST00000266688 2155 cGa/cAa 0 +PTPRS UCSF GRCh37 19 5231373 5231373 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 3 11 0 ENST00000357368.4:c.2103G>A p.Glu701= p.E701= ENST00000357368 NM_002850.3 701 gaG/gaA 0 +PTPRT UCSF GRCh37 20 41514503 41514503 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 10 29 0 ENST00000373187.1:c.158C>T p.Thr53Ile p.T53I ENST00000373187 53 aCc/aTc 0 +PTTG1IP UCSF GRCh37 21 46276217 46276217 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 13 26 0 ENST00000330938.3:c.340G>A p.Ala114Thr p.A114T ENST00000330938 NM_004339.3 114 Gcc/Acc 0 +PWP2 UCSF GRCh37 21 45550639 45550639 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 4 39 0 ENST00000291576.7:c.2746G>A p.Glu916Lys p.E916K ENST00000291576 NM_005049.2 916 Gag/Aag 0 +PXDNL UCSF GRCh37 8 52321585 52321585 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 20 30 0 ENST00000356297.4:c.2599C>T p.Pro867Ser p.P867S ENST00000356297 NM_144651.4 867 Ccc/Tcc 0 +PYGO2 UCSF GRCh37 1 154932010 154932010 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 9 21 0 ENST00000368457.2:c.466C>T p.Pro156Ser p.P156S ENST00000368457 NM_138300.3 156 Ccc/Tcc 0 +QARS UCSF GRCh37 3 49136792 49136792 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 7 28 0 ENST00000306125.6:c.1599C>T p.Asn533= p.N533= ENST00000306125 NM_001272073.1 533 aaC/aaT 0 +QKI UCSF GRCh37 6 163986999 163986999 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 29 60 0 ENST00000361752.3:c.935-754G>A *312* ENST00000361752 NM_006775.2 0 +RAB3GAP2 UCSF GRCh37 1 220340977 220340977 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 59 114 0 ENST00000358951.2:c.2847G>A p.Gln949= p.Q949= ENST00000358951 NM_012414.3 949 caG/caA 0 +RAB5B UCSF GRCh37 12 56380896 56380896 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 33 20 44 0 ENST00000360299.5:c.152G>A p.Ser51Asn p.S51N ENST00000360299 NM_002868.3 51 aGc/aAc 0 +RAB7A UCSF GRCh37 3 128514263 128514263 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 18 79 0 ENST00000265062.3:c.53G>A p.Gly18Glu p.G18E ENST00000265062 NM_004637.5 18 gGa/gAa 0 +RABL2A UCSF GRCh37 2 114392709 114392709 + splice_donor_variant Splice_Site SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 24 10 22 0 ENST00000393166.3:c.297+2T>C p.X99_splice ENST00000393166 0 +RAD17 UCSF GRCh37 5 68669849 68669849 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 100 17 119 0 ENST00000380774.3:c.235G>A p.Glu79Lys p.E79K ENST00000380774 NM_133339.2 79 Gaa/Aaa 0 +RAD50 UCSF GRCh37 5 131926937 131926937 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 104 23 95 0 ENST00000378823.3:c.1057G>A p.Glu353Lys p.E353K ENST00000378823 NM_005732.3 353 Gag/Aag 0 +RAG1 UCSF GRCh37 11 36595248 36595248 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 19 55 0 ENST00000299440.5:c.394C>T p.Pro132Ser p.P132S ENST00000299440 NM_000448.2 132 Cct/Tct 0 +RALGAPB UCSF GRCh37 20 37150153 37150153 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 56 45 102 0 ENST00000262879.6:c.1431A>G p.Gln477= p.Q477= ENST00000262879 477 caA/caG 0 +RALYL UCSF GRCh37 8 85441705 85441705 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 126 23 113 0 ENST00000521268.1:c.149G>A p.Gly50Glu p.G50E ENST00000521268 NM_173848.5 50 gGa/gAa 0 +RAPGEF2 UCSF GRCh37 4 160264305 160264305 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 32 96 0 ENST00000264431.4:c.2610C>T p.Phe870= p.F870= ENST00000264431 NM_014247.2 870 ttC/ttT 0 +RASA3 UCSF GRCh37 13 114766378 114766378 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 12 52 0 ENST00000334062.7:c.1773G>A p.Lys591= p.K591= ENST00000334062 NM_007368.2 591 aaG/aaA 0 +RASGRP1 UCSF GRCh37 15 38852131 38852131 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 23 45 0 ENST00000310803.5:c.111C>T p.Ser37= p.S37= ENST00000310803 NM_005739.3 37 tcC/tcT 0 +RASGRP3 UCSF GRCh37 2 33774783 33774783 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 183 31 170 0 ENST00000402538.3:c.1507C>T p.Leu503Phe p.L503F ENST00000402538 NM_170672.2 503 Ctc/Ttc 0 +RB1 UCSF GRCh37 13 49047527 49047527 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 44 36 101 0 ENST00000267163.4:c.2520+1G>A p.X840_splice ENST00000267163 NM_000321.2 0 +RBBP4 UCSF GRCh37 1 33134587 33134587 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 71 79 0 ENST00000373493.5:c.615G>A p.Trp205Ter p.W205* ENST00000373493 NM_005610.2 205 tgG/tgA 0 +RBL1 UCSF GRCh37 20 35672623 35672623 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 38 68 0 ENST00000373664.3:c.1636G>A p.Gly546Arg p.G546R ENST00000373664 NM_002895.3 546 Ggg/Agg 0 +RBM12 UCSF GRCh37 20 34241488 34241488 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 109 69 158 0 ENST00000359646.1:c.1757G>A p.Gly586Glu p.G586E ENST00000359646 586 gGa/gAa 0 +RBM12B UCSF GRCh37 8 94748329 94748329 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 107 60 121 0 ENST00000399300.2:c.310G>A p.Asp104Asn p.D104N ENST00000399300 NM_203390.2 104 Gac/Aac 0 +RBM5 UCSF GRCh37 3 50144935 50144935 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 3 40 0 ENST00000347869.3:c.974G>A p.Gly325Asp p.G325D ENST00000347869 NM_005778.3 325 gGt/gAt 0 +RBP3 UCSF GRCh37 10 48388081 48388081 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 13 16 0 ENST00000224600.4:c.2797C>T p.Leu933= p.L933= ENST00000224600 NM_002900.2 933 Ctg/Ttg 0 +RECQL UCSF GRCh37 12 21639413 21639413 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 10 46 0 ENST00000421138.2:c.501G>A p.Lys167= p.K167= ENST00000421138 167 aaG/aaA 0 +RECQL5 UCSF GRCh37 17 73625024 73625024 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 14 34 0 ENST00000317905.5:c.2479G>A p.Glu827Lys p.E827K ENST00000317905 NM_004259.6 827 Gag/Aag 0 +RELN UCSF GRCh37 7 103194156 103194156 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 18 66 0 ENST00000428762.1:c.5920C>T p.Pro1974Ser p.P1974S ENST00000428762 NM_005045.3 1974 Cct/Tct 0 +RELN UCSF GRCh37 7 103194216 103194216 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 70 8 87 0 ENST00000428762.1:c.5860C>T p.Pro1954Ser p.P1954S ENST00000428762 NM_005045.3 1954 Cct/Tct 0 +REN UCSF GRCh37 1 204124220 204124220 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 6 27 0 ENST00000272190.8:c.1145G>A p.Gly382Glu p.G382E ENST00000272190 NM_000537.3 382 gGg/gAg 0 +REPS1 UCSF GRCh37 6 139265669 139265669 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 92 47 117 0 ENST00000450536.2:c.719G>A p.Ser240Asn p.S240N ENST00000450536 NM_001286611.1 240 aGt/aAt 0 +RERE UCSF GRCh37 1 8526023 8526023 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 14 27 0 ENST00000337907.3:c.1165C>T p.Pro389Ser p.P389S ENST00000337907 NM_012102.3 389 Ccc/Tcc 0 +RERG UCSF GRCh37 12 15262121 15262121 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 24 65 0 ENST00000256953.2:c.523G>A p.Gly175Ser p.G175S ENST00000256953 NM_032918.2 175 Ggc/Agc 0 +RFWD3 UCSF GRCh37 16 74662375 74662375 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 23 69 0 ENST00000361070.4:c.1944G>A p.Arg648= p.R648= ENST00000361070 NM_018124.3 648 cgG/cgA 0 +RGL2 UCSF GRCh37 6 33263494 33263494 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 15 37 0 ENST00000497454.1:c.811C>T p.Leu271= p.L271= ENST00000497454 NM_004761.4 271 Ctg/Ttg 0 +RGMA UCSF GRCh37 15 93595396 93595396 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 4 10 0 ENST00000329082.7:c.472C>T p.Pro158Ser p.P158S ENST00000329082 NM_020211.2 158 Ccc/Tcc 0 +RGS22 UCSF GRCh37 8 101011541 101011541 + missense_variant Missense_Mutation SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 24 6 69 0 ENST00000360863.6:c.2898G>C p.Trp966Cys p.W966C ENST00000360863 NM_015668.3 966 tgG/tgC 0 +RGS3 UCSF GRCh37 9 116359220 116359220 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 6 28 0 ENST00000350696.5:c.3584G>A p.Ser1195Asn p.S1195N ENST00000350696 1195 aGt/aAt 0 +RHOBTB2 UCSF GRCh37 8 22861992 22861992 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 7 13 0 ENST00000251822.6:c.45C>T p.Ile15= p.I15= ENST00000251822 NM_015178.2 15 atC/atT 0 +RHOBTB2 UCSF GRCh37 8 22868110 22868110 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 25 40 0 ENST00000251822.6:c.1680C>T p.Thr560= p.T560= ENST00000251822 NM_015178.2 560 acC/acT 0 +RHOT2 UCSF GRCh37 16 720939 720939 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 4 9 0 ENST00000315082.4:c.687G>A p.Val229= p.V229= ENST00000315082 NM_138769.2 229 gtG/gtA 0 +RHOU UCSF GRCh37 1 228879096 228879096 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 93 63 138 0 ENST00000366691.3:c.386G>A p.Ser129Asn p.S129N ENST00000366691 NM_021205.5 129 aGt/aAt 0 +RHOU UCSF GRCh37 1 228879263 228879263 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 107 16 119 0 ENST00000366691.3:c.553G>A p.Glu185Lys p.E185K ENST00000366691 NM_021205.5 185 Gaa/Aaa 0 +RIC3 UCSF GRCh37 11 8161680 8161680 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 5 61 0 ENST00000309737.6:c.185C>T p.Thr62Ile p.T62I ENST00000309737 62 aCt/aTt 0 +RIF1 UCSF GRCh37 2 152314421 152314421 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 20 76 0 ENST00000243326.5:c.2799G>A p.Gln933= p.Q933= ENST00000243326 933 caG/caA 0 +RIN1 UCSF GRCh37 11 66102639 66102639 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 9 0 ENST00000311320.4:c.631C>T p.Pro211Ser p.P211S ENST00000311320 NM_004292.2 211 Cct/Tct 0 +RIOK2 UCSF GRCh37 5 96514771 96514771 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 82 14 91 0 ENST00000283109.3:c.193G>A p.Glu65Lys p.E65K ENST00000283109 NM_018343.2 65 Gag/Aag 0 +RIPK2 UCSF GRCh37 8 90775185 90775185 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 85 14 110 0 ENST00000220751.4:c.302G>A p.Gly101Glu p.G101E ENST00000220751 NM_003821.5 101 gGa/gAa 0 +RIPK3 UCSF GRCh37 14 24805471 24805471 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 18 32 0 ENST00000216274.5:c.1467G>A p.Gln489= p.Q489= ENST00000216274 NM_006871.3 489 caG/caA 0 +RNASEH1 UCSF GRCh37 2 3593451 3593451 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 136 31 57 0 ENST00000315212.3:c.785C>T p.Pro262Leu p.P262L ENST00000315212 NM_002936.3 262 cCt/cTt 0 +RNF122 UCSF GRCh37 8 33408577 33408577 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 135 28 120 0 ENST00000256257.1:c.255G>A p.Lys85= p.K85= ENST00000256257 NM_024787.3 85 aaG/aaA 0 +RNF141 UCSF GRCh37 11 10536554 10536554 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 11 87 0 ENST00000265981.2:c.602C>T p.Ser201Phe p.S201F ENST00000265981 NM_016422.3 201 tCt/tTt 0 +RNF157 UCSF GRCh37 17 74148449 74148449 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 23 63 0 ENST00000269391.6:c.1908G>A p.Glu636= p.E636= ENST00000269391 NM_052916.2 636 gaG/gaA 0 +RNF17 UCSF GRCh37 13 25424490 25424490 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 6 27 0 ENST00000255324.5:c.3113G>A p.Gly1038Glu p.G1038E ENST00000255324 NM_031277.2 1038 gGg/gAg 0 +RNF186 UCSF GRCh37 1 20141433 20141433 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 6 16 0 ENST00000375121.2:c.162G>A p.Lys54= p.K54= ENST00000375121 NM_019062.1 54 aaG/aaA 0 +RNF19A UCSF GRCh37 8 101273935 101273935 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 14 70 0 ENST00000341084.2:c.1517G>A p.Gly506Glu p.G506E ENST00000341084 NM_183419.3 506 gGa/gAa 0 +RNF20 UCSF GRCh37 9 104324237 104324237 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 163 69 144 0 ENST00000389120.3:c.2695C>T p.Pro899Ser p.P899S ENST00000389120 NM_019592.6 899 Cca/Tca 0 +RNF213 UCSF GRCh37 17 78321193 78321193 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 18 38 0 ENST00000582970.1:c.9058C>T p.Gln3020Ter p.Q3020* ENST00000582970 NM_001256071.1 3020 Cag/Tag 0 +RNF41 UCSF GRCh37 12 56602029 56602029 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 7 29 0 ENST00000345093.4:c.416G>A p.Arg139His p.R139H ENST00000345093 NM_005785.3 139 cGc/cAc 0 +RNF43 UCSF GRCh37 17 56435144 56435144 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 19 34 0 ENST00000407977.2:c.1993C>T p.Pro665Ser p.P665S ENST00000407977 665 Cct/Tct 0 +RNGTT UCSF GRCh37 6 89614661 89614661 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 20 89 0 ENST00000369485.4:c.457G>A p.Val153Ile p.V153I ENST00000369485 NM_003800.3 153 Gtt/Att 0 +RNLS UCSF GRCh37 10 90034789 90034789 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 8 44 0 ENST00000371947.3:c.877G>A p.Val293Ile p.V293I ENST00000371947 NM_018363.3 293 Gta/Ata 0 +RNMT UCSF GRCh37 18 13742486 13742486 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 42 140 0 ENST00000262173.3:c.975-1G>A p.X325_splice ENST00000262173 0 +ROBO1 UCSF GRCh37 3 78689011 78689011 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 17 33 0 ENST00000464233.1:c.2920C>T p.Pro974Ser p.P974S ENST00000464233 NM_002941.3 974 Cca/Tca 0 +ROCK1 UCSF GRCh37 18 18690815 18690815 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 84 19 71 0 ENST00000399799.2:c.57G>A p.Arg19= p.R19= ENST00000399799 NM_005406.2 19 cgG/cgA 0 +ROS1 UCSF GRCh37 6 117609783 117609783 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 27 74 0 ENST00000368508.3:c.6916G>A p.Glu2306Lys p.E2306K ENST00000368508 NM_002944.2 2306 Gag/Aag 0 +ROS1 UCSF GRCh37 6 117686340 117686340 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 37 83 0 ENST00000368508.3:c.3001C>T p.Pro1001Ser p.P1001S ENST00000368508 NM_002944.2 1001 Cct/Tct 0 +RP1L1 UCSF GRCh37 8 10464582 10464582 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 122 26 84 0 ENST00000382483.3:c.7026G>A p.Arg2342= p.R2342= ENST00000382483 NM_178857.5 2342 agG/agA 0 +RP1L1 UCSF GRCh37 8 10468188 10468188 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 13 30 0 ENST00000382483.3:c.3420G>A p.Arg1140= p.R1140= ENST00000382483 NM_178857.5 1140 agG/agA 0 +RPAP1 UCSF GRCh37 15 41809836 41809836 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 21 97 0 ENST00000304330.4:c.4086G>A p.Glu1362= p.E1362= ENST00000304330 NM_015540.2 1362 gaG/gaA 0 +RPF1 UCSF GRCh37 1 84945059 84945059 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 10 30 0 ENST00000370654.5:c.95G>A p.Gly32Glu p.G32E ENST00000370654 NM_025065.6 32 gGg/gAg 0 +RPGRIP1 UCSF GRCh37 14 21793437 21793437 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 19 63 0 ENST00000400017.2:c.2262G>A p.Leu754= p.L754= ENST00000400017 NM_020366.3 754 ctG/ctA 0 +RPL30 UCSF GRCh37 8 99057222 99057222 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 55 103 0 ENST00000287038.3:c.116G>A p.Arg39Lys p.R39K ENST00000287038 NM_000989.3 39 aGa/aAa 0 +RPL7 UCSF GRCh37 8 74204984 74204984 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 78 98 0 ENST00000352983.2:c.63G>A p.Lys21= p.K21= ENST00000352983 21 aaG/aaA 0 +RPS16 UCSF GRCh37 19 39924353 39924353 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 15 60 0 ENST00000251453.3:c.199G>A p.Asp67Asn p.D67N ENST00000251453 NM_001020.4 67 Gac/Aac 0 +RPS27A UCSF GRCh37 2 55462702 55462702 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 117 16 122 0 ENST00000272317.6:c.460G>A p.Glu154Lys p.E154K ENST00000272317 NM_002954.5 154 Gaa/Aaa 0 +RRP12 UCSF GRCh37 10 99141531 99141531 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 12 15 0 ENST00000370992.4:c.1261G>A p.Val421Met p.V421M ENST00000370992 NM_015179.3 421 Gtg/Atg 0 +RRP8 UCSF GRCh37 11 6622723 6622723 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 27 27 0 ENST00000254605.6:c.573G>A p.Arg191= p.R191= ENST00000254605 NM_015324.3 191 cgG/cgA 0 +RS1 UCSF GRCh37 X 18674867 18674867 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 8 26 35 0 ENST00000379984.3:c.90G>A p.Glu30= p.E30= ENST00000379984 NM_000330.3 30 gaG/gaA 0 +RSAD1 UCSF GRCh37 17 48559607 48559607 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 5 14 0 ENST00000258955.2:c.630G>A p.Gly210= p.G210= ENST00000258955 NM_018346.1 210 ggG/ggA 0 +RTN4IP1 UCSF GRCh37 6 107035715 107035715 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 20 59 0 ENST00000369063.3:c.829G>A p.Val277Ile p.V277I ENST00000369063 NM_032730.4 277 Gtt/Att 0 +RXRB UCSF GRCh37 6 33162485 33162485 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 5 22 0 ENST00000374680.3:c.1576C>T p.Leu526Phe p.L526F ENST00000374680 NM_021976.4 526 Ctt/Ttt 0 +RYK UCSF GRCh37 3 133894806 133894806 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 25 99 0 ENST00000296084.4:c.1386C>T p.Val462= p.V462= ENST00000296084 NM_001005861.2 462 gtC/gtT 0 +RYR3 UCSF GRCh37 15 34015071 34015071 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 121 16 84 0 ENST00000389232.4:c.6775C>T p.Pro2259Ser p.P2259S ENST00000389232 NM_001036.3 2259 Ccc/Tcc 0 +S100A7A UCSF GRCh37 1 153390636 153390636 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 26 63 0 ENST00000329256.2:c.78G>A p.Lys26= p.K26= ENST00000329256 26 aaG/aaA 0 +S1PR4 UCSF GRCh37 19 3179754 3179754 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 7 19 0 ENST00000246115.3:c.964C>T p.Leu322Phe p.L322F ENST00000246115 NM_003775.3 322 Ctc/Ttc 0 +SAG UCSF GRCh37 2 234229373 234229373 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 10 22 0 ENST00000409110.1:c.279G>A p.Gln93= p.Q93= ENST00000409110 NM_000541.4 93 caG/caA 0 +SART3 UCSF GRCh37 12 108930558 108930558 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 21 41 0 ENST00000228284.3:c.1313C>T p.Ser438Phe p.S438F ENST00000228284 NM_014706.3 438 tCc/tTc 0 +SATL1 UCSF GRCh37 X 84362618 84362618 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 7 22 0 ENST00000395409.3:c.796C>T p.Gln266Ter p.Q266* ENST00000395409 266 Caa/Taa 0 +SBF1 UCSF GRCh37 22 50893373 50893373 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 5 12 0 ENST00000380817.3:c.4682G>A p.Gly1561Glu p.G1561E ENST00000380817 NM_002972.2 1561 gGg/gAg 0 +SBF2 UCSF GRCh37 11 9871647 9871647 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 48 24 80 0 ENST00000256190.8:c.2729A>G p.Gln910Arg p.Q910R ENST00000256190 NM_030962.3 910 cAg/cGg 0 +SCAF4 UCSF GRCh37 21 33068918 33068918 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 18 4 23 0 ENST00000286835.7:c.923C>T p.Pro308Leu p.P308L ENST00000286835 NM_020706.2 308 cCc/cTc 0 +SCAMP4 UCSF GRCh37 19 1918968 1918968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 23 27 0 ENST00000316097.8:c.374G>A p.Gly125Asp p.G125D ENST00000316097 NM_079834.2 125 gGc/gAc 0 +SCAPER UCSF GRCh37 15 77092596 77092596 + missense_variant Missense_Mutation SNP T T G NOVEL P01_Rec Untested WXS Illumina HiSeq 75 60 120 0 ENST00000324767.7:c.604A>C p.Asn202His p.N202H ENST00000324767 NM_020843.2 202 Aat/Cat 0 +SCARA3 UCSF GRCh37 8 27528549 27528549 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 3 21 0 ENST00000301904.3:c.1502C>T p.Pro501Leu p.P501L ENST00000301904 NM_016240.2 501 cCt/cTt 0 +SCARB1 UCSF GRCh37 12 125298883 125298883 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 3 47 31 0 ENST00000415380.2:c.495C>T p.Thr165= p.T165= ENST00000415380 165 acC/acT 0 +SCD UCSF GRCh37 10 102112124 102112124 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 17 56 0 ENST00000370355.2:c.312G>A p.Gly104= p.G104= ENST00000370355 NM_005063.4 104 ggG/ggA 0 +SCN11A UCSF GRCh37 3 38888991 38888991 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 23 59 0 ENST00000302328.3:c.4570C>T p.Pro1524Ser p.P1524S ENST00000302328 NM_014139.2 1524 Cca/Tca 0 +SCN1A UCSF GRCh37 2 166895998 166895998 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 15 82 0 ENST00000303395.4:c.2524C>T p.Leu842Phe p.L842F ENST00000303395 842 Ctt/Ttt 0 +SCN2A UCSF GRCh37 2 166165874 166165874 + synonymous_variant Silent SNP G G A snp132_rs2228983 P01_Rec Untested WXS Illumina HiSeq 69 44 97 0 ENST00000283256.6:c.618G>A p.Glu206= p.E206= ENST00000283256 NM_021007.2 206 gaG/gaA 0 +SCN4A UCSF GRCh37 17 62021109 62021109 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 8 46 0 ENST00000435607.1:c.4014C>T p.Pro1338= p.P1338= ENST00000435607 NM_000334.4 1338 ccC/ccT 0 +SCNN1B UCSF GRCh37 16 23392077 23392077 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 25 16 0 ENST00000343070.2:c.1878G>A p.Gln626= p.Q626= ENST00000343070 NM_000336.2 626 caG/caA 0 +SEC11C UCSF GRCh37 18 56819825 56819825 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 113 30 133 0 ENST00000587834.1:c.255G>A p.Arg85= p.R85= ENST00000587834 NM_033280.2 85 cgG/cgA 0 +SEC23B UCSF GRCh37 20 18508219 18508219 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 182 37 180 0 ENST00000262544.2:c.1073G>A p.Gly358Glu p.G358E ENST00000262544 358 gGa/gAa 0 +SEC23B UCSF GRCh37 20 18522964 18522964 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 124 15 110 0 ENST00000262544.2:c.1429G>A p.Gly477Ser p.G477S ENST00000262544 477 Ggc/Agc 0 +SEC24B UCSF GRCh37 4 110402884 110402884 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 72 48 84 0 ENST00000265175.5:c.1112C>T p.Pro371Leu p.P371L ENST00000265175 NM_006323.2 371 cCc/cTc 0 +SEL1L3 UCSF GRCh37 4 25849177 25849177 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 74 61 98 0 ENST00000399878.3:c.472G>A p.Asp158Asn p.D158N ENST00000399878 NM_015187.3 158 Gat/Aat 0 +SELE UCSF GRCh37 1 169702801 169702801 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 12 64 0 ENST00000333360.7:c.-48G>A p.X16_splice ENST00000333360 NM_000450.2 0 +SELE UCSF GRCh37 1 169702111 169702111 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 36 58 0 ENST00000333360.7:c.66G>A p.Trp22Ter p.W22* ENST00000333360 NM_000450.2 22 tgG/tgA 0 +SELRC1 UCSF GRCh37 1 53158423 53158423 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 10 47 0 ENST00000371538.3:c.223G>A p.Gly75Arg p.G75R ENST00000371538 NM_023077.2 75 Ggg/Agg 0 +SEMA3D UCSF GRCh37 7 84628924 84628924 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 31 55 0 ENST00000284136.6:c.2166C>T p.Ser722= p.S722= ENST00000284136 NM_152754.2 722 agC/agT 0 +SERINC2 UCSF GRCh37 1 31899568 31899568 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 11 38 0 ENST00000373709.3:c.678C>T p.Tyr226= p.Y226= ENST00000373709 NM_178865.4 226 taC/taT 0 +SERPINA6 UCSF GRCh37 14 94772555 94772555 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 6 21 0 ENST00000341584.3:c.885C>T p.Ser295= p.S295= ENST00000341584 NM_001756.3 295 agC/agT 0 +SERPINE1 UCSF GRCh37 7 100773852 100773852 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 102 64 105 0 ENST00000223095.4:c.422G>A p.Arg141Gln p.R141Q ENST00000223095 NM_000602.4 141 cGg/cAg 0 +SERPINE2 UCSF GRCh37 2 224866420 224866420 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 18 27 0 ENST00000258405.4:c.198G>A p.Gln66= p.Q66= ENST00000258405 NM_001136528.1 66 caG/caA 0 +SERPINF1 UCSF GRCh37 17 1679946 1679946 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 20 52 0 ENST00000254722.4:c.907C>T p.Arg303Ter p.R303* ENST00000254722 NM_002615.5 303 Cga/Tga 0 +SERPING1 UCSF GRCh37 11 57367484 57367484 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 9 55 0 ENST00000278407.4:c.184G>A p.Val62Ile p.V62I ENST00000278407 NM_000062.2 62 Gtt/Att 0 +SESN3 UCSF GRCh37 11 94911935 94911935 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 42 91 0 ENST00000536441.1:c.995G>A p.Gly332Asp p.G332D ENST00000536441 NM_144665.3 332 gGt/gAt 0 +SETD1A UCSF GRCh37 16 30977082 30977082 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 7 9 0 ENST00000262519.8:c.1880C>T p.Pro627Leu p.P627L ENST00000262519 NM_014712.1 627 cCc/cTc 0 +SETD2 UCSF GRCh37 3 47098404 47098404 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 4 45 0 ENST00000409792.3:c.6870G>A p.Gln2290= p.Q2290= ENST00000409792 NM_014159.6 2290 caG/caA 0 +SETD5 UCSF GRCh37 3 9483374 9483374 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 86 59 142 0 ENST00000402198.1:c.908G>A p.Gly303Glu p.G303E ENST00000402198 NM_001080517.1 303 gGg/gAg 0 +SEZ6 UCSF GRCh37 17 27296849 27296849 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 4 15 0 ENST00000317338.12:c.980C>T p.Thr327Ile p.T327I ENST00000317338 327 aCc/aTc 0 +SEZ6 UCSF GRCh37 17 27284412 27284412 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 31 77 0 ENST00000317338.12:c.2448C>T p.Arg816= p.R816= ENST00000317338 816 cgC/cgT 0 +SFSWAP UCSF GRCh37 12 132210037 132210037 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 14 56 0 ENST00000261674.4:c.694G>A p.Ala232Thr p.A232T ENST00000261674 NM_004592.3 232 Gcc/Acc 0 +SFTPD UCSF GRCh37 10 81702620 81702620 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 13 33 0 ENST00000372292.3:c.215C>T p.Ala72Val p.A72V ENST00000372292 NM_003019.4 72 gCa/gTa 0 +SFXN5 UCSF GRCh37 2 73215423 73215423 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 8 16 0 ENST00000272433.2:c.589C>T p.Leu197Phe p.L197F ENST00000272433 NM_144579.2 197 Ctt/Ttt 0 +SGIP1 UCSF GRCh37 1 67142712 67142712 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 26 59 0 ENST00000371037.4:c.672G>A p.Trp224Ter p.W224* ENST00000371037 NM_032291.2 224 tgG/tgA 0 +SGK1 UCSF GRCh37 6 134493417 134493417 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 89 21 114 0 ENST00000237305.7:c.700G>A p.Gly234Arg p.G234R ENST00000237305 NM_005627.3 234 Gga/Aga 0 +SGK223 UCSF GRCh37 8 8235518 8235518 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 16 29 0 ENST00000520004.1:c.401G>A p.Gly134Asp p.G134D ENST00000520004 134 gGc/gAc 0 +SH3D21 UCSF GRCh37 1 36786324 36786324 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 15 35 0 ENST00000453908.2:c.2060G>A p.Gly687Glu p.G687E ENST00000453908 NM_001162530.1 687 gGa/gAa 0 +SH3PXD2A UCSF GRCh37 10 105386875 105386875 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 9 30 0 ENST00000369774.4:c.689C>T p.Ser230Phe p.S230F ENST00000369774 230 tCc/tTc 0 +SH3PXD2A UCSF GRCh37 10 105561100 105561100 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 28 0 ENST00000369774.4:c.93C>T p.Thr31= p.T31= ENST00000369774 31 acC/acT 0 +SH3RF2 UCSF GRCh37 5 145379823 145379823 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 5 21 0 ENST00000359120.4:c.581C>T p.Ala194Val p.A194V ENST00000359120 NM_152550.3 194 gCc/gTc 0 +SH3TC1 UCSF GRCh37 4 8221106 8221106 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 13 0 ENST00000245105.3:c.961C>T p.Pro321Ser p.P321S ENST00000245105 NM_018986.3 321 Ccc/Tcc 0 +SHANK2 UCSF GRCh37 11 70332216 70332216 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 6 31 0 ENST00000423696.2:c.3045C>T p.Pro1015= p.P1015= ENST00000423696 1015 ccC/ccT 0 +SIM1 UCSF GRCh37 6 100911214 100911214 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 30 59 0 ENST00000262901.4:c.131G>A p.Arg44Lys p.R44K ENST00000262901 NM_005068.2 44 aGa/aAa 0 +SIRPB1 UCSF GRCh37 20 1552408 1552408 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 10 39 0 ENST00000381605.4:c.709G>A p.Asp237Asn p.D237N ENST00000381605 NM_006065.3 237 Gac/Aac 0 +SLAMF6 UCSF GRCh37 1 160458953 160458953 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 63 7 38 0 ENST00000368057.3:c.804C>T p.Ser268= p.S268= ENST00000368057 268 tcC/tcT 0 +SLC12A6 UCSF GRCh37 15 34526102 34526102 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 16 47 0 ENST00000354181.3:c.3433G>A p.Val1145Met p.V1145M ENST00000354181 1145 Gtg/Atg 0 +SLC15A3 UCSF GRCh37 11 60708694 60708694 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 15 0 ENST00000227880.3:c.1176C>T p.Arg392= p.R392= ENST00000227880 NM_016582.2 392 cgC/cgT 0 +SLC1A5 UCSF GRCh37 19 47280365 47280365 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 5 20 22 0 ENST00000542575.2:c.1255G>A p.Val419Ile p.V419I ENST00000542575 NM_005628.2 419 Gtc/Atc 0 +SLC1A6 UCSF GRCh37 19 15061096 15061096 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 6 19 0 ENST00000221742.3:c.1606C>T p.Leu536Phe p.L536F ENST00000221742 NM_005071.2 536 Ctc/Ttc 0 +SLC22A16 UCSF GRCh37 6 110746096 110746096 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 90 55 115 0 ENST00000368919.3:c.1714G>A p.Asp572Asn p.D572N ENST00000368919 NM_033125.3 572 Gat/Aat 0 +SLC22A20 UCSF GRCh37 11 64985117 64985117 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 9 19 0 ENST00000525264.1:n.622G>A *208* ENST00000525264 0 +SLC24A1 UCSF GRCh37 15 65916651 65916651 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 49 72 0 ENST00000261892.6:c.233G>A p.Ser78Asn p.S78N ENST00000261892 NM_004727.2 78 aGc/aAc 0 +SLC25A37 UCSF GRCh37 8 23429182 23429182 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.008,1000g2011may_all_0.0299,snp132_rs34146184 P01_Rec Untested WXS Illumina HiSeq 55 12 53 0 ENST00000519973.1:c.831C>T p.Gly277= p.G277= ENST00000519973 NM_016612.2 277 ggC/ggT 0 +SLC26A2 UCSF GRCh37 5 149357685 149357685 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 21 88 0 ENST00000286298.4:c.470C>T p.Ser157Phe p.S157F ENST00000286298 NM_000112.3 157 tCc/tTc 0 +SLC26A8 UCSF GRCh37 6 35912088 35912088 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 94 40 80 0 ENST00000355574.2:c.2502C>T p.Ser834= p.S834= ENST00000355574 NM_001193476.1 834 agC/agT 0 +SLC27A6 UCSF GRCh37 5 128351585 128351585 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 35 91 0 ENST00000262462.4:c.977G>A p.Gly326Glu p.G326E ENST00000262462 326 gGa/gAa 0 +SLC28A2 UCSF GRCh37 15 45556211 45556211 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 10 70 0 ENST00000347644.3:c.579C>T p.His193= p.H193= ENST00000347644 NM_004212.3 193 caC/caT 0 +SLC2A12 UCSF GRCh37 6 134350161 134350161 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 63 34 126 0 ENST00000275230.5:c.802C>T p.Leu268= p.L268= ENST00000275230 NM_145176.2 268 Ctg/Ttg 0 +SLC2A4 UCSF GRCh37 17 7186928 7186928 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 22 49 0 ENST00000317370.8:c.287C>T p.Ser96Phe p.S96F ENST00000317370 NM_001042.2 96 tCc/tTc 0 +SLC30A1 UCSF GRCh37 1 211749417 211749417 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 121 21 121 0 ENST00000367001.4:c.837G>A p.Gly279= p.G279= ENST00000367001 NM_021194.2 279 ggG/ggA 0 +SLC30A3 UCSF GRCh37 2 27479746 27479746 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 8 15 0 ENST00000233535.4:c.793G>A p.Ala265Thr p.A265T ENST00000233535 NM_003459.4 265 Gcc/Acc 0 +SLC30A5 UCSF GRCh37 5 68425286 68425286 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 9 86 0 ENST00000396591.3:c.2140C>T p.Leu714Phe p.L714F ENST00000396591 NM_022902.4 714 Ctt/Ttt 0 +SLC30A8 UCSF GRCh37 8 118175722 118175722 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 66 0 ENST00000456015.2:c.782C>T p.Ala261Val p.A261V ENST00000456015 NM_173851.2 261 gCc/gTc 0 +SLC34A3 UCSF GRCh37 9 140127052 140127052 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 4 9 0 ENST00000361134.2:c.201C>T p.Arg67= p.R67= ENST00000361134 NM_080877.2 67 cgC/cgT 0 +SLC35F5 UCSF GRCh37 2 114512853 114512853 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 72 10 87 0 ENST00000245680.2:c.162C>T p.Asn54= p.N54= ENST00000245680 NM_025181.2 54 aaC/aaT 0 +SLC38A9 UCSF GRCh37 5 54948412 54948412 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 27 67 0 ENST00000318672.3:c.897C>T p.Leu299= p.L299= ENST00000318672 299 ctC/ctT 0 +SLC39A4 UCSF GRCh37 8 145637955 145637955 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 8 32 0 ENST00000301305.3:c.1911G>A p.Leu637= p.L637= ENST00000301305 NM_130849.3 637 ctG/ctA 0 +SLC39A6 UCSF GRCh37 18 33704519 33704519 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 30 74 0 ENST00000269187.5:c.934G>A p.Ala312Thr p.A312T ENST00000269187 NM_012319.3 312 Gct/Act 0 +SLC44A5 UCSF GRCh37 1 75693542 75693542 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 17 72 0 ENST00000370855.5:c.854G>A p.Gly285Glu p.G285E ENST00000370855 NM_152697.4 285 gGa/gAa 0 +SLC4A5 UCSF GRCh37 2 74459741 74459741 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 12 24 0 ENST00000346834.4:c.2629G>A p.Val877Met p.V877M ENST00000346834 877 Gtg/Atg 0 +SLC4A8 UCSF GRCh37 12 51855017 51855017 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 7 49 0 ENST00000453097.2:c.1043G>A p.Gly348Glu p.G348E ENST00000453097 NM_001039960.2 348 gGg/gAg 0 +SLC5A9 UCSF GRCh37 1 48701422 48701422 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 7 19 0 ENST00000438567.2:c.1163C>T p.Ala388Val p.A388V ENST00000438567 NM_001011547.2 388 gCc/gTc 0 +SLC6A12 UCSF GRCh37 12 309904 309904 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 44 43 0 ENST00000359674.4:c.624C>T p.Ser208= p.S208= ENST00000359674 NM_001122847.2 208 tcC/tcT 0 +SLC7A8 UCSF GRCh37 14 23635544 23635544 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 12 72 0 ENST00000316902.7:c.356+1G>A p.X119_splice ENST00000316902 NM_012244.3 0 +SLC9A10 UCSF GRCh37 3 111981803 111981803 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 34 95 0 ENST00000305815.5:c.1165C>T p.Leu389Phe p.L389F ENST00000305815 NM_183061.1 389 Ctt/Ttt 0 +SLC9A11 UCSF GRCh37 1 173517646 173517646 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 13 64 0 ENST00000367714.3:c.1343C>T p.Ala448Val p.A448V ENST00000367714 NM_178527.3 448 gCc/gTc 0 +SLC9A5 UCSF GRCh37 16 67291332 67291332 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 24 51 0 ENST00000299798.11:c.1420G>A p.Glu474Lys p.E474K ENST00000299798 NM_004594.2 474 Gaa/Aaa 0 +SLCO5A1 UCSF GRCh37 8 70650373 70650373 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 24 64 0 ENST00000260126.4:c.1325C>T p.Thr442Ile p.T442I ENST00000260126 NM_030958.2 442 aCa/aTa 0 +SLITRK5 UCSF GRCh37 13 88330363 88330363 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 12 58 0 ENST00000325089.6:c.2720G>A p.Gly907Glu p.G907E ENST00000325089 NM_015567.1 907 gGg/gAg 0 +SLMAP UCSF GRCh37 3 57846543 57846543 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 19 45 0 ENST00000428312.1:c.805G>A p.Val269Ile p.V269I ENST00000428312 269 Gtt/Att 0 +SLMO2 UCSF GRCh37 20 57613588 57613588 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 32 68 0 ENST00000355937.4:c.134C>T p.Pro45Leu p.P45L ENST00000355937 NM_016045.2 45 cCc/cTc 0 +SMAP1 UCSF GRCh37 6 71508401 71508401 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 19 85 0 ENST00000370455.3:c.537G>A p.Lys179= p.K179= ENST00000370455 NM_001281440.1 179 aaG/aaA 0 +SMARCA2 UCSF GRCh37 9 2039702 2039702 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 11 25 0 ENST00000349721.2:c.592C>T p.Leu198Phe p.L198F ENST00000349721 NM_003070.3 198 Ctc/Ttc 0 +SMARCC2 UCSF GRCh37 12 56567624 56567624 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 51 67 0 ENST00000267064.4:c.1506C>T p.Ala502= p.A502= ENST00000267064 NM_003075.3 502 gcC/gcT 0 +SMARCD1 UCSF GRCh37 12 50484110 50484110 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 15 62 0 ENST00000394963.4:c.960G>A p.Trp320Ter p.W320* ENST00000394963 NM_003076.4 320 tgG/tgA 0 +SMC6 UCSF GRCh37 2 17897360 17897360 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 47 108 0 ENST00000351948.4:c.1518C>T p.Gly506= p.G506= ENST00000351948 NM_024624.5 506 ggC/ggT 0 +SMC6 UCSF GRCh37 2 17897456 17897456 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 49 56 109 0 ENST00000351948.4:c.1422T>C p.Thr474= p.T474= ENST00000351948 NM_024624.5 474 acT/acC 0 +SMCHD1 UCSF GRCh37 18 2697853 2697853 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 14 76 0 ENST00000320876.6:c.1156G>A p.Val386Ile p.V386I ENST00000320876 NM_015295.2 386 Gta/Ata 0 +SMEK2 UCSF GRCh37 2 55825776 55825776 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 44 115 0 ENST00000345102.5:c.697G>A p.Ala233Thr p.A233T ENST00000345102 NM_001122964.1 233 Gct/Act 0 +SMG7 UCSF GRCh37 1 183515267 183515267 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P01_Rec Untested WXS Illumina HiSeq 7 0 ENST00000347615.2:c.2545del p.Met849Ter p.M849* ENST00000347615 NM_173156.2 846 gAa/ga 0 +SMURF1 UCSF GRCh37 7 98649907 98649907 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 11 38 0 ENST00000361125.1:c.642C>T p.Asn214= p.N214= ENST00000361125 NM_020429.2 214 aaC/aaT 0 +SMURF2 UCSF GRCh37 17 62559045 62559045 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 28 56 0 ENST00000262435.9:c.1056G>A p.Val352= p.V352= ENST00000262435 NM_022739.3 352 gtG/gtA 0 +SNAP47 UCSF GRCh37 1 227935657 227935657 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 7 40 0 ENST00000315781.5:c.355G>A p.Gly119Ser p.G119S ENST00000315781 119 Ggc/Agc 0 +SND1 UCSF GRCh37 7 127447556 127447556 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 16 76 0 ENST00000354725.3:c.1171C>T p.Arg391Cys p.R391C ENST00000354725 NM_014390.2 391 Cgt/Tgt 0 +SNRPA UCSF GRCh37 19 41268881 41268881 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 17 0 ENST00000243563.3:c.502G>A p.Gly168Ser p.G168S ENST00000243563 NM_004596.4 168 Ggt/Agt 0 +SNX4 UCSF GRCh37 3 125223584 125223584 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 23 64 0 ENST00000251775.4:c.146C>T p.Thr49Ile p.T49I ENST00000251775 NM_003794.3 49 aCa/aTa 0 +SNX4 UCSF GRCh37 3 125179650 125179650 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 4 55 0 ENST00000251775.4:c.909G>A p.Gln303= p.Q303= ENST00000251775 NM_003794.3 303 caG/caA 0 +SON UCSF GRCh37 21 34932013 34932013 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 93 15 146 0 ENST00000356577.4:c.6589C>T p.Pro2197Ser p.P2197S ENST00000356577 NM_138927.2 2197 Cct/Tct 0 +SORBS3 UCSF GRCh37 8 22424195 22424195 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 13 0 ENST00000240123.7:c.1112G>A p.Gly371Glu p.G371E ENST00000240123 NM_005775.4 371 gGg/gAg 0 +SOS2 UCSF GRCh37 14 50597331 50597331 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 15 82 0 ENST00000216373.5:c.3225G>A p.Glu1075= p.E1075= ENST00000216373 NM_006939.2 1075 gaG/gaA 0 +SOX13 UCSF GRCh37 1 204082180 204082180 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 3 10 0 ENST00000367204.1:c.137C>T p.Pro46Leu p.P46L ENST00000367204 NM_005686.2 46 cCt/cTt 0 +SP140 UCSF GRCh37 2 231101935 231101935 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 35 0 ENST00000392045.3:c.197G>A p.Gly66Asp p.G66D ENST00000392045 NM_007237.4 66 gGc/gAc 0 +SPACA7 UCSF GRCh37 13 113053461 113053461 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 19 65 0 ENST00000283550.3:c.323G>A p.Gly108Asp p.G108D ENST00000283550 NM_145248.4 108 gGc/gAc 0 +SPAG1 UCSF GRCh37 8 101232598 101232598 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 50 106 0 ENST00000251809.3:c.1627G>A p.Asp543Asn p.D543N ENST00000251809 NM_172218.2 543 Gat/Aat 0 +SPAG11B UCSF GRCh37 8 7320246 7320246 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 15 95 0 ENST00000297498.2:c.197G>A p.Arg66His p.R66H ENST00000297498 NM_016512.3 66 cGc/cAc 0 +SPAG9 UCSF GRCh37 17 49068013 49068013 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 16 47 0 ENST00000262013.7:c.2415C>T p.Asp805= p.D805= ENST00000262013 NM_001130528.2 805 gaC/gaT 0 +SPANXN4 UCSF GRCh37 X 142121991 142121991 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 11 35 0 ENST00000446864.1:c.259G>A p.Asp87Asn p.D87N ENST00000446864 NM_001009613.2 87 Gac/Aac 0 +SPATA20 UCSF GRCh37 17 48627611 48627611 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 6 36 0 ENST00000356488.4:c.988C>T p.His330Tyr p.H330Y ENST00000356488 NM_001258372.1 330 Cac/Tac 0 +SPATA6 UCSF GRCh37 1 48865249 48865249 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 87 30 87 0 ENST00000371847.3:c.554G>A p.Arg185Lys p.R185K ENST00000371847 NM_019073.2 185 aGa/aAa 0 +SPDYE4 UCSF GRCh37 17 8656648 8656648 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 13 20 0 ENST00000328794.6:c.645G>A p.Glu215= p.E215= ENST00000328794 NM_001128076.1 215 gaG/gaA 0 +SPEF2 UCSF GRCh37 5 35759703 35759703 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 129 18 137 0 ENST00000356031.3:c.3502C>T p.Leu1168Phe p.L1168F ENST00000356031 NM_024867.3 1168 Ctc/Ttc 0 +SPEG UCSF GRCh37 2 220338590 220338590 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 12 19 0 ENST00000312358.7:c.4412G>A p.Gly1471Asp p.G1471D ENST00000312358 NM_005876.4 1471 gGc/gAc 0 +SPHKAP UCSF GRCh37 2 228884573 228884573 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 155 23 141 0 ENST00000392056.3:c.997G>A p.Glu333Lys p.E333K ENST00000392056 NM_001142644.1 333 Gaa/Aaa 0 +SPHKAP UCSF GRCh37 2 228855860 228855860 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 12 50 0 ENST00000392056.3:c.4815G>A p.Gln1605= p.Q1605= ENST00000392056 NM_001142644.1 1605 caG/caA 0 +SPO11 UCSF GRCh37 20 55909861 55909861 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 20 41 0 ENST00000371263.3:c.566G>A p.Gly189Asp p.G189D ENST00000371263 NM_012444.2 189 gGc/gAc 0 +SPTA1 UCSF GRCh37 1 158639310 158639310 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 76 66 105 0 ENST00000368147.4:c.1721G>A p.Arg574Lys p.R574K ENST00000368147 NM_003126.2 574 aGa/aAa 0 +SPTA1 UCSF GRCh37 1 158655131 158655131 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 11 69 0 ENST00000368147.4:c.31G>A p.Glu11Lys p.E11K ENST00000368147 NM_003126.2 11 Gag/Aag 0 +SPTAN1 UCSF GRCh37 9 131337077 131337077 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 75 27 56 0 ENST00000372731.4:c.487G>A p.Asp163Asn p.D163N ENST00000372731 NM_003127.3 163 Gac/Aac 0 +SPTAN1 UCSF GRCh37 9 131337540 131337540 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 33 91 0 ENST00000372731.4:c.567G>A p.Lys189= p.K189= ENST00000372731 NM_003127.3 189 aaG/aaA 0 +SRCIN1 UCSF GRCh37 17 36708983 36708983 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 29 50 0 ENST00000264659.7:c.2310G>A p.Gly770= p.G770= ENST00000264659 NM_025248.2 770 ggG/ggA 0 +SRD5A2 UCSF GRCh37 2 31758811 31758811 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 28 48 0 ENST00000405650.1:n.473C>T *158* ENST00000405650 0 +SRRM2 UCSF GRCh37 16 2817289 2817289 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 10 31 0 ENST00000301740.8:c.6760G>A p.Val2254Met p.V2254M ENST00000301740 NM_016333.3 2254 Gtg/Atg 0 +SRRM2 UCSF GRCh37 16 2807494 2807494 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 25 59 0 ENST00000301740.8:c.264G>A p.Gln88= p.Q88= ENST00000301740 NM_016333.3 88 caG/caA 0 +SRRT UCSF GRCh37 7 100482407 100482407 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 9 25 0 ENST00000347433.4:c.989G>A p.Gly330Asp p.G330D ENST00000347433 330 gGt/gAt 0 +SRSF1 UCSF GRCh37 17 56082832 56082832 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 92 19 70 0 ENST00000258962.4:c.682C>T p.Pro228Ser p.P228S ENST00000258962 NM_006924.4 228 Cca/Tca 0 +SS18 UCSF GRCh37 18 23658055 23658055 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 15 66 0 ENST00000415083.2:c.216G>A p.Gln72= p.Q72= ENST00000415083 NM_001007559.1 72 caG/caA 0 +SSH2 UCSF GRCh37 17 28004719 28004719 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 30 72 0 ENST00000269033.3:c.439G>A p.Asp147Asn p.D147N ENST00000269033 NM_033389.2 147 Gac/Aac 0 +SSPO UCSF GRCh37 7 149484482 149484482 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 9 41 0 ENST00000378016.2:n.3405C>T *1135* ENST00000378016 0 +SSTR2 UCSF GRCh37 17 71166313 71166313 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 85 11 47 0 ENST00000357585.2:c.855C>T p.Ser285= p.S285= ENST00000357585 NM_001050.2 285 agC/agT 0 +SSX1 UCSF GRCh37 X 48123289 48123289 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 22 72 0 ENST00000376919.3:c.403G>A p.Asp135Asn p.D135N ENST00000376919 NM_005635.3 135 Gat/Aat 0 +ST18 UCSF GRCh37 8 53028885 53028885 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 25 50 0 ENST00000276480.7:c.2953C>T p.Leu985= p.L985= ENST00000276480 NM_014682.2 985 Cta/Tta 0 +ST3GAL5 UCSF GRCh37 2 86090527 86090527 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 41 47 0 ENST00000377332.3:c.164G>A p.Ser55Asn p.S55N ENST00000377332 NM_003896.3 55 aGc/aAc 0 +ST8SIA1 UCSF GRCh37 12 22440198 22440198 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 7 53 0 ENST00000396037.4:c.266C>T p.Ala89Val p.A89V ENST00000396037 NM_003034.3 89 gCc/gTc 0 +STAG1 UCSF GRCh37 3 136341997 136341997 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 24 125 0 ENST00000383202.2:c.123C>T p.Gly41= p.G41= ENST00000383202 NM_005862.2 41 ggC/ggT 0 +STAG3 UCSF GRCh37 7 99808690 99808690 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 12 23 0 ENST00000317296.5:c.3295C>T p.Leu1099= p.L1099= ENST00000317296 NM_012447.2 1099 Ctg/Ttg 0 +STARD13 UCSF GRCh37 13 33686902 33686902 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 110 17 94 0 ENST00000336934.5:c.2448C>T p.Pro816= p.P816= ENST00000336934 NM_178006.3 816 ccC/ccT 0 +STAT5A UCSF GRCh37 17 40447808 40447808 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 5 21 0 ENST00000345506.4:c.547C>T p.Gln183Ter p.Q183* ENST00000345506 NM_003152.3 183 Caa/Taa 0 +STC2 UCSF GRCh37 5 172744859 172744859 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 63 12 85 0 ENST00000265087.4:c.900C>T p.Ile300= p.I300= ENST00000265087 NM_003714.2 300 atC/atT 0 +STEAP1 UCSF GRCh37 7 89790512 89790512 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 120 15 121 0 ENST00000297205.2:c.478A>G p.Thr160Ala p.T160A ENST00000297205 NM_012449.2 160 Aca/Gca 0 +STIL UCSF GRCh37 1 47767251 47767251 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 30 73 0 ENST00000360380.3:c.435C>T p.Asp145= p.D145= ENST00000360380 NM_001282936.1 145 gaC/gaT 0 +STIM1 UCSF GRCh37 11 4091387 4091387 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 27 41 0 ENST00000300737.4:c.745G>A p.Glu249Lys p.E249K ENST00000300737 NM_003156.3 249 Gag/Aag 0 +STK17B UCSF GRCh37 2 197021289 197021289 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 41 78 0 ENST00000263955.4:c.209G>A p.Gly70Glu p.G70E ENST00000263955 NM_004226.3 70 gGa/gAa 0 +STK35 UCSF GRCh37 20 2083970 2083970 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 6 14 0 ENST00000381482.3:c.851G>A p.Ser284Asn p.S284N ENST00000381482 284 aGc/aAc 0 +STMN3 UCSF GRCh37 20 62275234 62275234 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 4 15 21 0 ENST00000370053.1:c.166G>A p.Val56Ile p.V56I ENST00000370053 NM_015894.3 56 Gtc/Atc 0 +STXBP5 UCSF GRCh37 6 147685202 147685202 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 111 21 121 0 ENST00000321680.6:c.2981G>A p.Arg994Lys p.R994K ENST00000321680 NM_001127715.2 994 aGa/aAa 0 +SUGP1 UCSF GRCh37 19 19420913 19420913 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 18 36 0 ENST00000247001.5:c.303C>T p.Thr101= p.T101= ENST00000247001 NM_172231.3 101 acC/acT 0 +SULT1A2 UCSF GRCh37 16 28603601 28603601 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 11 49 0 ENST00000335715.4:c.758C>T p.Ser253Phe p.S253F ENST00000335715 NM_001054.3 253 tCc/tTc 0 +SUPT5H UCSF GRCh37 19 39949503 39949503 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 9 40 0 ENST00000432763.2:c.365C>T p.Ala122Val p.A122V ENST00000432763 NM_001111020.2 122 gCt/gTt 0 +SUPT6H UCSF GRCh37 17 27008350 27008350 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 12 44 0 ENST00000314616.6:c.1426C>T p.Pro476Ser p.P476S ENST00000314616 NM_003170.3 476 Cct/Tct 0 +SWAP70 UCSF GRCh37 11 9746358 9746358 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 42 95 0 ENST00000318950.6:c.568G>A p.Gly190Ser p.G190S ENST00000318950 NM_015055.2 190 Ggc/Agc 0 +SYCE2 UCSF GRCh37 19 13010179 13010179 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 17 36 0 ENST00000293695.7:c.633G>A p.Gln211= p.Q211= ENST00000293695 NM_001105578.1 211 caG/caA 0 +SYCP1 UCSF GRCh37 1 115400096 115400096 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 15 56 0 ENST00000369518.1:c.269G>A p.Gly90Glu p.G90E ENST00000369518 90 gGa/gAa 0 +SYF2 UCSF GRCh37 1 25549922 25549922 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 134 27 115 0 ENST00000236273.4:c.567G>A p.Gln189= p.Q189= ENST00000236273 NM_015484.4 189 caG/caA 0 +SYNE2 UCSF GRCh37 14 64519153 64519153 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 15 89 0 ENST00000344113.4:c.8522C>T p.Ala2841Val p.A2841V ENST00000344113 NM_015180.4 2841 gCt/gTt 0 +SYNM UCSF GRCh37 15 99670863 99670863 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 22 44 0 ENST00000336292.6:c.2295C>T p.Val765= p.V765= ENST00000336292 NM_145728.2 765 gtC/gtT 0 +SYNPO2 UCSF GRCh37 4 119944628 119944628 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 25 69 0 ENST00000429713.2:c.149G>A p.Gly50Glu p.G50E ENST00000429713 NM_001128933.1 50 gGa/gAa 0 +SYNPO2L UCSF GRCh37 10 75414027 75414027 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 3 9 0 ENST00000394810.2:c.117G>A p.Arg39= p.R39= ENST00000394810 NM_001114133.1 39 cgG/cgA 0 +SYNRG UCSF GRCh37 17 35946594 35946594 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 9 65 0 ENST00000339208.6:c.304C>T p.Leu102= p.L102= ENST00000339208 NM_001163544.1 102 Ctg/Ttg 0 +SYPL2 UCSF GRCh37 1 110022032 110022032 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 29 35 0 ENST00000369872.3:c.681C>T p.Ala227= p.A227= ENST00000369872 NM_001040709.1 227 gcC/gcT 0 +SYTL2 UCSF GRCh37 11 85447625 85447625 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 15 60 0 ENST00000528231.1:c.502C>T p.Pro168Ser p.P168S ENST00000528231 NM_001162951.1 168 Cca/Tca 0 +SYVN1 UCSF GRCh37 11 64898470 64898470 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 17 40 0 ENST00000377190.3:c.862G>A p.Asp288Asn p.D288N ENST00000377190 NM_172230.2 288 Gac/Aac 0 +SYVN1 UCSF GRCh37 11 64899725 64899725 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 15 28 0 ENST00000377190.3:c.525C>T p.Gly175= p.G175= ENST00000377190 NM_172230.2 175 ggC/ggT 0 +TAB2 UCSF GRCh37 6 149699780 149699780 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 46 113 0 ENST00000367456.1:c.729C>T p.Asn243= p.N243= ENST00000367456 243 aaC/aaT 0 +TACC2 UCSF GRCh37 10 123846070 123846070 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 1 13 24 0 ENST00000334433.3:c.4055G>A p.Gly1352Asp p.G1352D ENST00000334433 1352 gGt/gAt 0 +TACC2 UCSF GRCh37 10 123903218 123903218 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 4 24 0 ENST00000334433.3:c.5831G>A p.Ser1944Asn p.S1944N ENST00000334433 1944 aGc/aAc 0 +TACR1 UCSF GRCh37 2 75347752 75347752 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 28 36 0 ENST00000305249.5:c.532G>A p.Val178Ile p.V178I ENST00000305249 NM_001058.3 178 Gtc/Atc 0 +TADA2A UCSF GRCh37 17 35802753 35802753 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 9 73 0 ENST00000394395.2:c.531G>A p.Glu177= p.E177= ENST00000394395 NM_001166105.1 177 gaG/gaA 0 +TAF1L UCSF GRCh37 9 32630947 32630947 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 103 56 165 0 ENST00000242310.4:c.4631C>T p.Ser1544Phe p.S1544F ENST00000242310 NM_153809.2 1544 tCt/tTt 0 +TAF3 UCSF GRCh37 10 7866448 7866448 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 46 126 0 ENST00000344293.5:c.334C>T p.Pro112Ser p.P112S ENST00000344293 NM_031923.3 112 Cct/Tct 0 +TAGAP UCSF GRCh37 6 159457737 159457737 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 72 11 72 0 ENST00000367066.3:c.1318C>T p.Leu440= p.L440= ENST00000367066 NM_054114.4 440 Ctg/Ttg 0 +TAOK3 UCSF GRCh37 12 118627651 118627651 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 50 103 0 ENST00000392533.3:c.1290G>A p.Arg430= p.R430= ENST00000392533 NM_016281.3 430 cgG/cgA 0 +TARBP1 UCSF GRCh37 1 234563473 234563473 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 8 56 0 ENST00000040877.1:c.3100G>A p.Gly1034Arg p.G1034R ENST00000040877 NM_005646.3 1034 Gga/Aga 0 +TAS1R1 UCSF GRCh37 1 6634898 6634898 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 12 17 0 ENST00000333172.6:c.706G>A p.Gly236Arg p.G236R ENST00000333172 NM_138697.3 236 Ggg/Agg 0 +TAS2R30 UCSF GRCh37 12 11286113 11286113 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 127 50 124 0 ENST00000539585.1:c.731C>T p.Ser244Phe p.S244F ENST00000539585 NM_001097643.1 244 tCc/tTc 0 +TAS2R31 UCSF GRCh37 12 11183443 11183443 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 93 63 154 0 ENST00000390675.2:c.492G>A p.Trp164Ter p.W164* ENST00000390675 NM_176885.2 164 tgG/tgA 0 +TAS2R60 UCSF GRCh37 7 143140762 143140762 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 40 74 0 ENST00000332690.1:c.217G>A p.Val73Ile p.V73I ENST00000332690 NM_177437.1 73 Gta/Ata 0 +TBC1D1 UCSF GRCh37 4 38134768 38134768 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 62 70 0 ENST00000261439.4:c.3196G>A p.Glu1066Lys p.E1066K ENST00000261439 NM_015173.3 1066 Gaa/Aaa 0 +TBC1D10A UCSF GRCh37 22 30691779 30691779 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 6 11 0 ENST00000215790.7:c.471C>T p.Asp157= p.D157= ENST00000215790 NM_031937.2 157 gaC/gaT 0 +TBC1D25 UCSF GRCh37 X 48419031 48419031 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 8 48 0 ENST00000376771.4:c.1735G>A p.Val579Ile p.V579I ENST00000376771 NM_002536.2 579 Gta/Ata 0 +TBC1D30 UCSF GRCh37 12 65232609 65232609 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 69 85 0 ENST00000539867.1:c.910G>A p.Ala304Thr p.A304T ENST00000539867 NM_015279.1 304 Gct/Act 0 +TBCD UCSF GRCh37 17 80884302 80884302 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 32 62 0 ENST00000355528.4:c.2406C>T p.Thr802= p.T802= ENST00000355528 NM_005993.4 802 acC/acT 0 +TCEB3 UCSF GRCh37 1 24077496 24077496 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 26 54 0 ENST00000418390.2:c.479G>A p.Arg160Lys p.R160K ENST00000418390 NM_003198.2 160 aGg/aAg 0 +TCF3 UCSF GRCh37 19 1612371 1612371 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 5 19 0 ENST00000262965.5:c.1823-523G>A *608* ENST00000262965 NM_003200.3 0 +TCF7L1 UCSF GRCh37 2 85510672 85510672 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 88 56 71 0 ENST00000282111.3:c.496G>A p.Asp166Asn p.D166N ENST00000282111 NM_031283.2 166 Gac/Aac 0 +TCN2 UCSF GRCh37 22 31018968 31018968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 33 84 0 ENST00000215838.3:c.1120G>A p.Ala374Thr p.A374T ENST00000215838 374 Gcc/Acc 0 +TCP11 UCSF GRCh37 6 35107840 35107840 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 37 93 0 ENST00000512012.1:c.124+684C>T *42* ENST00000512012 0 +TCP11L1 UCSF GRCh37 11 33094171 33094171 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 93 20 91 0 ENST00000334274.4:c.1479C>T p.Val493= p.V493= ENST00000334274 NM_018393.3 493 gtC/gtT 0 +TDO2 UCSF GRCh37 4 156824919 156824919 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 32 77 0 ENST00000536354.2:c.9G>A p.Gly3= p.G3= ENST00000536354 NM_005651.3 3 ggG/ggA 0 +TDRD7 UCSF GRCh37 9 100245182 100245182 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 110 28 109 0 ENST00000355295.4:c.2464C>T p.Pro822Ser p.P822S ENST00000355295 NM_014290.2 822 Cct/Tct 0 +TECPR1 UCSF GRCh37 7 97862967 97862967 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 10 18 0 ENST00000447648.2:c.1438C>T p.Pro480Ser p.P480S ENST00000447648 NM_015395.2 480 Ccc/Tcc 0 +TENC1 UCSF GRCh37 12 53453653 53453653 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 10 19 0 ENST00000314250.6:c.2228G>A p.Gly743Glu p.G743E ENST00000314250 NM_170754.2 743 gGg/gAg 0 +TET2 UCSF GRCh37 4 106164085 106164085 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 48 22 60 0 ENST00000380013.4:c.3594+1G>A p.X1198_splice ENST00000380013 NM_001127208.2 0 +TET2 UCSF GRCh37 4 106157043 106157043 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 28 61 0 ENST00000380013.4:c.1944C>T p.Asp648= p.D648= ENST00000380013 NM_001127208.2 648 gaC/gaT 0 +TET2 UCSF GRCh37 4 106155153 106155153 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 18 48 0 ENST00000380013.4:c.54G>A p.Leu18= p.L18= ENST00000380013 NM_001127208.2 18 ctG/ctA 0 +TEX11 UCSF GRCh37 X 69811660 69811660 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 3 14 20 0 ENST00000344304.3:c.2126G>A p.Ser709Asn p.S709N ENST00000344304 709 aGt/aAt 0 +TEX11 UCSF GRCh37 X 69749812 69749812 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 3 43 41 0 ENST00000344304.3:c.2603T>C p.Val868Ala p.V868A ENST00000344304 868 gTc/gCc 0 +TFEC UCSF GRCh37 7 115596785 115596785 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 129 20 117 0 ENST00000265440.7:c.330G>A p.Gly110= p.G110= ENST00000265440 NM_012252.3 110 ggG/ggA 0 +TFIP11 UCSF GRCh37 22 26892785 26892785 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 11 53 0 ENST00000405938.1:c.1507C>T p.Pro503Ser p.P503S ENST00000405938 NM_001008697.1 503 Ccg/Tcg 0 +TG UCSF GRCh37 8 134144132 134144132 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 22 110 0 ENST00000220616.4:c.7939G>A p.Glu2647Lys p.E2647K ENST00000220616 NM_003235.4 2647 Gag/Aag 0 +TGFB2 UCSF GRCh37 1 218609363 218609363 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 67 0 ENST00000366930.4:c.806C>T p.Ser269Phe p.S269F ENST00000366930 NM_003238.3 269 tCc/tTc 0 +TGIF1 UCSF GRCh37 18 3456459 3456459 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 133 25 81 0 ENST00000330513.5:c.511C>T p.Leu171= p.L171= ENST00000330513 NM_170695.3 171 Cta/Tta 0 +TGM2 UCSF GRCh37 20 36766720 36766720 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 31 34 0 ENST00000361475.2:c.1410G>A p.Glu470= p.E470= ENST00000361475 NM_004613.2 470 gaG/gaA 0 +TGM7 UCSF GRCh37 15 43584920 43584920 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 50 114 0 ENST00000452443.2:c.426C>T p.Asn142= p.N142= ENST00000452443 NM_052955.2 142 aaC/aaT 0 +THSD7A UCSF GRCh37 7 11676112 11676112 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 23 39 0 ENST00000423059.4:c.667G>A p.Ala223Thr p.A223T ENST00000423059 NM_015204.2 223 Gcg/Acg 0 +THYN1 UCSF GRCh37 11 134118731 134118731 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 24 65 0 ENST00000341541.3:c.603G>A p.Gln201= p.Q201= ENST00000341541 NM_014174.2 201 caG/caA 0 +TIGD2 UCSF GRCh37 4 90034848 90034848 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 22 61 0 ENST00000317005.2:c.723C>T p.Asp241= p.D241= ENST00000317005 NM_145715.2 241 gaC/gaT 0 +TIMELESS UCSF GRCh37 12 56827356 56827357 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 0 ENST00000553532.1:c.332dup p.Leu111PhefsTer17 p.L111Ffs*17 ENST00000553532 111 ttg/tTtg 0 +TIPARP UCSF GRCh37 3 156421390 156421390 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 5 40 85 0 ENST00000295924.7:c.1425G>A p.Arg475= p.R475= ENST00000295924 NM_015508.4 475 cgG/cgA 0 +TLN2 UCSF GRCh37 15 63076025 63076025 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 4 32 0 ENST00000306829.6:c.5672C>T p.Thr1891Ile p.T1891I ENST00000306829 NM_015059.2 1891 aCc/aTc 0 +TLR1 UCSF GRCh37 4 38799895 38799895 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 26 76 0 ENST00000308979.2:c.558C>T p.Asp186= p.D186= ENST00000308979 NM_003263.3 186 gaC/gaT 0 +TM7SF3 UCSF GRCh37 12 27128458 27128458 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 34 100 0 ENST00000343028.4:c.1421C>T p.Ala474Val p.A474V ENST00000343028 NM_016551.2 474 gCt/gTt 0 +TMC3 UCSF GRCh37 15 81648787 81648787 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 4 18 0 ENST00000359440.5:c.891+1G>A p.X297_splice ENST00000359440 NM_001080532.1 0 +TMC3 UCSF GRCh37 15 81633784 81633784 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 23 52 0 ENST00000359440.5:c.1791C>T p.Ser597= p.S597= ENST00000359440 NM_001080532.1 597 agC/agT 0 +TMEFF2 UCSF GRCh37 2 193059093 193059093 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 28 39 0 ENST00000272771.5:c.158G>A p.Gly53Asp p.G53D ENST00000272771 NM_016192.2 53 gGc/gAc 0 +TMEM106A UCSF GRCh37 17 41368603 41368603 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 52 77 0 ENST00000588659.1:c.565G>A p.Glu189Lys p.E189K ENST00000588659 189 Gaa/Aaa 0 +TMEM108 UCSF GRCh37 3 133114716 133114716 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 12 32 0 ENST00000321871.6:c.1614C>T p.Leu538= p.L538= ENST00000321871 NM_001136469.1 538 ctC/ctT 0 +TMEM132E UCSF GRCh37 17 32964821 32964821 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 7 18 0 ENST00000321639.5:c.2525C>T p.Ser842Phe p.S842F ENST00000321639 NM_207313.1 842 tCt/tTt 0 +TMEM173 UCSF GRCh37 5 138857072 138857072 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 5 29 0 ENST00000330794.4:c.788C>T p.Thr263Ile p.T263I ENST00000330794 NM_198282.2 263 aCc/aTc 0 +TMEM188 UCSF GRCh37 16 50063641 50063641 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 7 58 0 ENST00000427478.2:c.103C>T p.Leu35Phe p.L35F ENST00000427478 NM_001281789.1 35 Ctt/Ttt 0 +TMEM196 UCSF GRCh37 7 19765226 19765226 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 27 54 0 ENST00000405764.3:c.370C>T p.Leu124Phe p.L124F ENST00000405764 NM_152774.3 124 Ctc/Ttc 0 +TMEM202 UCSF GRCh37 15 72699426 72699426 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 13 28 0 ENST00000341689.3:c.488-1G>A p.X163_splice ENST00000341689 NM_001080462.1 0 +TMEM214 UCSF GRCh37 2 27263055 27263055 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 5 48 0 ENST00000238788.9:c.1780C>T p.Leu594Phe p.L594F ENST00000238788 NM_017727.4 594 Ctc/Ttc 0 +TMEM22 UCSF GRCh37 3 136573939 136573939 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 56 94 0 ENST00000393079.3:c.637C>T p.Leu213Phe p.L213F ENST00000393079 NM_001097600.1 213 Ctc/Ttc 0 +TMEM26 UCSF GRCh37 10 63195995 63195995 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 8 33 0 ENST00000399298.3:c.203C>T p.Ala68Val p.A68V ENST00000399298 NM_178505.6 68 gCc/gTc 0 +TMEM40 UCSF GRCh37 3 12791328 12791328 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 23 35 0 ENST00000264728.8:c.4G>A p.Glu2Lys p.E2K ENST00000264728 2 Gag/Aag 0 +TMEM45A UCSF GRCh37 3 100277310 100277310 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 44 82 0 ENST00000323523.4:c.465G>A p.Leu155= p.L155= ENST00000323523 NM_018004.1 155 ctG/ctA 0 +TMEM59 UCSF GRCh37 1 54502382 54502382 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 11 85 0 ENST00000234831.5:c.717G>A p.Gly239= p.G239= ENST00000234831 NM_004872.3 239 ggG/ggA 0 +TMEM72 UCSF GRCh37 10 45430347 45430347 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 40 74 0 ENST00000389583.4:c.593C>T p.Ala198Val p.A198V ENST00000389583 NM_001123376.1 198 gCc/gTc 0 +TMPRSS11E UCSF GRCh37 4 69362515 69362515 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 163 34 226 0 ENST00000305363.4:c.1265G>A p.Gly422Asp p.G422D ENST00000305363 NM_014058.3 422 gGt/gAt 0 +TMPRSS6 UCSF GRCh37 22 37462896 37462896 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 10 17 0 ENST00000346753.3:c.2247C>T p.Gly749= p.G749= ENST00000346753 NM_153609.2 749 ggC/ggT 0 +TMPRSS7 UCSF GRCh37 3 111793177 111793177 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 17 107 0 ENST00000452346.2:c.1701C>T p.Gly567= p.G567= ENST00000452346 567 ggC/ggT 0 +TNC UCSF GRCh37 9 117853202 117853202 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.00296 P01_Rec Untested WXS Illumina HiSeq 49 20 47 0 ENST00000350763.4:c.96G>A p.Lys32= p.K32= ENST00000350763 NM_002160.3 32 aaG/aaA 0 +TNFRSF13C UCSF GRCh37 22 42321421 42321421 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 12 10 0 ENST00000291232.3:c.505G>A p.Gly169Ser p.G169S ENST00000291232 NM_052945.3 169 Ggc/Agc 0 +TNFRSF14 UCSF GRCh37 1 2493248 2493248 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 22 39 0 ENST00000355716.4:c.688C>T p.Pro230Ser p.P230S ENST00000355716 NM_003820.2 230 Cca/Tca 0 +TNFRSF8 UCSF GRCh37 1 12186062 12186062 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 6 26 0 ENST00000263932.2:c.1208C>T p.Ala403Val p.A403V ENST00000263932 NM_001243.3 403 gCc/gTc 0 +TNIK UCSF GRCh37 3 170784468 170784468 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 8 55 0 ENST00000436636.2:c.3756G>A p.Met1252Ile p.M1252I ENST00000436636 NM_015028.2 1252 atG/atA 0 +TNRC18 UCSF GRCh37 7 5399192 5399192 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 49 76 0 ENST00000430969.1:c.4670G>A p.Ser1557Asn p.S1557N ENST00000430969 NM_001080495.2 1557 aGc/aAc 0 +TNS1 UCSF GRCh37 2 218712366 218712366 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 27 27 0 ENST00000171887.4:c.2499G>A p.Gln833= p.Q833= ENST00000171887 NM_022648.4 833 caG/caA 0 +TNS4 UCSF GRCh37 17 38633947 38633947 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 8 23 0 ENST00000254051.6:c.2041C>T p.Pro681Ser p.P681S ENST00000254051 NM_032865.5 681 Cct/Tct 0 +TOM1 UCSF GRCh37 22 35742963 35742963 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 27 0 ENST00000449058.2:c.1324+1G>A p.X442_splice ENST00000449058 NM_005488.2 0 +TOM1L1 UCSF GRCh37 17 53016303 53016303 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 9 45 0 ENST00000575882.1:c.1052C>T p.Ser351Phe p.S351F ENST00000575882 NM_005486.2 351 tCt/tTt 0 +TOP2A UCSF GRCh37 17 38572281 38572281 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 10 93 0 ENST00000423485.1:c.308C>T p.Ser103Phe p.S103F ENST00000423485 NM_001067.3 103 tCt/tTt 0 +TOX UCSF GRCh37 8 59720800 59720800 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 15 67 0 ENST00000361421.1:c.1421C>T p.Thr474Ile p.T474I ENST00000361421 NM_014729.2 474 aCt/aTt 0 +TP53 UCSF GRCh37 17 7578527 7578527 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 8 8 15 0 ENST00000269305.4:c.403T>C p.Cys135Arg p.C135R ENST00000269305 NM_001126112.2 135 Tgc/Cgc 0 +TP53 UCSF GRCh37 17 7579310 7579310 + splice_donor_variant Splice_Site SNP A A C NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 17 19 55 0 ENST00000269305.4:c.375+2T>G p.X125_splice ENST00000269305 NM_001126112.2 0 +TP53I13 UCSF GRCh37 17 27898710 27898710 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 65 8 29 0 ENST00000301057.7:c.285C>T p.Thr95= p.T95= ENST00000301057 NM_138349.2 95 acC/acT 0 +TPCN2 UCSF GRCh37 11 68840147 68840147 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 4 13 0 ENST00000294309.3:c.1114G>A p.Asp372Asn p.D372N ENST00000294309 NM_139075.3 372 Gac/Aac 0 +TPPP2 UCSF GRCh37 14 21498789 21498789 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 6 13 0 ENST00000321760.6:c.49G>A p.Glu17Lys p.E17K ENST00000321760 NM_173846.4 17 Gaa/Aaa 0 +TPR UCSF GRCh37 1 186310473 186310473 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 46 79 0 ENST00000367478.4:c.3799G>A p.Glu1267Lys p.E1267K ENST00000367478 NM_003292.2 1267 Gaa/Aaa 0 +TPRG1L UCSF GRCh37 1 3542308 3542308 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 18 22 0 ENST00000378344.2:c.325C>T p.Leu109= p.L109= ENST00000378344 NM_182752.3 109 Ctg/Ttg 0 +TPX2 UCSF GRCh37 20 30366771 30366771 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 14 77 0 ENST00000300403.6:c.1038C>T p.Ser346= p.S346= ENST00000300403 NM_012112.4 346 agC/agT 0 +TRAF1 UCSF GRCh37 9 123675816 123675816 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 6 15 0 ENST00000373887.3:c.495C>T p.Tyr165= p.Y165= ENST00000373887 NM_005658.4 165 taC/taT 0 +TRAF3 UCSF GRCh37 14 103355934 103355934 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 29 94 0 ENST00000392745.2:c.689G>A p.Ser230Asn p.S230N ENST00000392745 230 aGc/aAc 0 +TRAF3IP1 UCSF GRCh37 2 239234489 239234489 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 31 93 0 ENST00000373327.4:c.232G>A p.Asp78Asn p.D78N ENST00000373327 NM_015650.3 78 Gac/Aac 0 +TRAF3IP1 UCSF GRCh37 2 239234494 239234494 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 34 87 0 ENST00000373327.4:c.237G>A p.Val79= p.V79= ENST00000373327 NM_015650.3 79 gtG/gtA 0 +TRAF7 UCSF GRCh37 16 2223935 2223935 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 20 34 0 ENST00000326181.6:c.1149G>A p.Gln383= p.Q383= ENST00000326181 NM_032271.2 383 caG/caA 0 +TRANK1 UCSF GRCh37 3 36897308 36897308 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 28 132 0 ENST00000429976.2:c.3773G>A p.Ser1258Asn p.S1258N ENST00000429976 1258 aGt/aAt 0 +TRANK1 UCSF GRCh37 3 36902590 36902590 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 16 103 0 ENST00000429976.2:c.1170C>T p.Phe390= p.F390= ENST00000429976 390 ttC/ttT 0 +TRAPPC10 UCSF GRCh37 21 45522744 45522744 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 19 29 0 ENST00000291574.4:c.3432G>A p.Arg1144= p.R1144= ENST00000291574 NM_003274.4 1144 agG/agA 0 +TRIB3 UCSF GRCh37 20 368870 368870 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 4 15 0 ENST00000217233.3:c.216C>T p.Val72= p.V72= ENST00000217233 NM_021158.3 72 gtC/gtT 0 +TRIM10 UCSF GRCh37 6 30122090 30122090 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 8 18 0 ENST00000449742.2:c.1102G>A p.Val368Met p.V368M ENST00000449742 NM_006778.3 368 Gtg/Atg 0 +TRIM33 UCSF GRCh37 1 114967346 114967346 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 35 24 59 0 ENST00000358465.2:c.1727A>G p.Gln576Arg p.Q576R ENST00000358465 NM_015906.3 576 cAa/cGa 0 +TRIM45 UCSF GRCh37 1 117663497 117663497 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 7 35 0 ENST00000256649.4:c.327G>A p.Lys109= p.K109= ENST00000256649 NM_025188.3 109 aaG/aaA 0 +TRIO UCSF GRCh37 5 14369561 14369561 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 20 22 0 ENST00000344204.4:c.3145C>T p.Pro1049Ser p.P1049S ENST00000344204 NM_007118.2 1049 Cca/Tca 0 +TRIO UCSF GRCh37 5 14368959 14368959 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 13 59 0 ENST00000344204.4:c.3017G>A p.Arg1006His p.R1006H ENST00000344204 NM_007118.2 1006 cGc/cAc 0 +TRIO UCSF GRCh37 5 14359496 14359496 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 19 40 0 ENST00000344204.4:c.2247C>T p.Pro749= p.P749= ENST00000344204 NM_007118.2 749 ccC/ccT 0 +TRMT1L UCSF GRCh37 1 185108515 185108515 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 8 36 0 ENST00000367506.5:c.1306G>A p.Val436Ile p.V436I ENST00000367506 NM_001202423.1 436 Gta/Ata 0 +TRPC4AP UCSF GRCh37 20 33637770 33637770 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 19 77 0 ENST00000252015.2:c.556G>A p.Glu186Lys p.E186K ENST00000252015 186 Gaa/Aaa 0 +TRPM2 UCSF GRCh37 21 45798961 45798961 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 7 22 0 ENST00000300482.5:c.1096G>A p.Val366Met p.V366M ENST00000300482 366 Gtg/Atg 0 +TRPM7 UCSF GRCh37 15 50935715 50935715 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 40 94 0 ENST00000313478.7:c.357C>T p.Val119= p.V119= ENST00000313478 NM_017672.4 119 gtC/gtT 0 +TRPS1 UCSF GRCh37 8 116430604 116430604 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 112 17 94 0 ENST00000220888.5:c.2738G>A p.Gly913Asp p.G913D ENST00000220888 913 gGc/gAc 0 +TRPV3 UCSF GRCh37 17 3427628 3427628 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 30 42 0 ENST00000576742.1:c.1607C>T p.Ser536Phe p.S536F ENST00000576742 NM_145068.3 536 tCt/tTt 0 +TRRAP UCSF GRCh37 7 98529278 98529278 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 51 0 ENST00000359863.4:c.3842C>T p.Pro1281Leu p.P1281L ENST00000359863 NM_001244580.1 1281 cCc/cTc 0 +TRRAP UCSF GRCh37 7 98567904 98567904 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 15 13 0 ENST00000359863.4:c.7661C>T p.Ser2554Phe p.S2554F ENST00000359863 NM_001244580.1 2554 tCc/tTc 0 +TSHR UCSF GRCh37 14 81610572 81610572 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 53 116 0 ENST00000541158.2:c.2170G>A p.Val724Ile p.V724I ENST00000541158 724 Gtt/Att 0 +TSHZ2 UCSF GRCh37 20 51870400 51870400 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 34 49 0 ENST00000371497.5:c.403G>A p.Asp135Asn p.D135N ENST00000371497 NM_173485.5 135 Gat/Aat 0 +TSPAN10 UCSF GRCh37 17 79612115 79612115 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 6 25 0 ENST00000328585.4:c.134G>A p.Cys45Tyr p.C45Y ENST00000328585 NM_031945.3 45 tGc/tAc 0 +TSPY8 UCSF GRCh37 Y 9196995 9196995 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 12 77 0 ENST00000287721.9:c.708G>A p.Glu236= p.E236= ENST00000287721 NM_001243721.1 236 gaG/gaA 0 +TSSK1B UCSF GRCh37 5 112769861 112769861 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 8 41 0 ENST00000390666.3:c.676C>T p.Arg226Cys p.R226C ENST00000390666 NM_032028.3 226 Cgt/Tgt 0 +TSTA3 UCSF GRCh37 8 144698315 144698315 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 29 54 0 ENST00000425753.2:c.222G>A p.Gly74= p.G74= ENST00000425753 NM_003313.3 74 ggG/ggA 0 +TTC25 UCSF GRCh37 17 40117175 40117175 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 13 31 0 ENST00000377540.1:n.1078G>A *360* ENST00000377540 0 +TTC28 UCSF GRCh37 22 28559236 28559236 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 38 61 0 ENST00000397906.2:c.1285G>A p.Glu429Lys p.E429K ENST00000397906 NM_001145418.1 429 Gag/Aag 0 +TTLL4 UCSF GRCh37 2 219610436 219610436 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 5 9 0 ENST00000258398.4:c.1809G>A p.Gln603= p.Q603= ENST00000258398 603 caG/caA 0 +TTLL9 UCSF GRCh37 20 30526972 30526972 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 11 24 0 ENST00000375938.4:c.1146G>A p.Gly382= p.G382= ENST00000375938 382 ggG/ggA 0 +TTN UCSF GRCh37 2 179394972 179394972 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 143 23 146 0 ENST00000591111.1:c.101447G>A p.Gly33816Glu p.G33816E ENST00000591111 33816 gGa/gAa 0 +TTN UCSF GRCh37 2 179456088 179456088 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 195 33 171 0 ENST00000591111.1:c.55441G>A p.Asp18481Asn p.D18481N ENST00000591111 18481 Gat/Aat 0 +TTN UCSF GRCh37 2 179483047 179483047 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 125 84 182 0 ENST00000591111.1:c.42215G>A p.Ser14072Asn p.S14072N ENST00000591111 14072 aGt/aAt 0 +TTN UCSF GRCh37 2 179426824 179426824 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 180 21 158 0 ENST00000591111.1:c.79112C>T p.Ser26371Phe p.S26371F ENST00000591111 26371 tCt/tTt 0 +TTN UCSF GRCh37 2 179500785 179500785 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 53 108 0 ENST00000591111.1:c.36590C>T p.Thr12197Ile p.T12197I ENST00000591111 12197 aCc/aTc 0 +TTN UCSF GRCh37 2 179411986 179411986 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 131 31 122 0 ENST00000591111.1:c.89343C>T p.Ala29781= p.A29781= ENST00000591111 29781 gcC/gcT 0 +TUB UCSF GRCh37 11 8123085 8123085 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 31 0 ENST00000299506.2:c.1440G>A p.Met480Ile p.M480I ENST00000299506 NM_177972.2 480 atG/atA 0 +TUBAL3 UCSF GRCh37 10 5436047 5436047 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 40 47 0 ENST00000380419.3:c.774C>T p.Asp258= p.D258= ENST00000380419 NM_024803.2 258 gaC/gaT 0 +TUBGCP2 UCSF GRCh37 10 135102493 135102493 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 26 44 0 ENST00000252936.3:c.1392C>T p.Gly464= p.G464= ENST00000252936 464 ggC/ggT 0 +TUBGCP3 UCSF GRCh37 13 113201934 113201934 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 13 50 0 ENST00000261965.3:c.1168G>A p.Gly390Arg p.G390R ENST00000261965 NM_006322.4 390 Gga/Aga 0 +TULP1 UCSF GRCh37 6 35480615 35480615 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 4 16 0 ENST00000229771.6:c.21C>T p.Thr7= p.T7= ENST00000229771 NM_003322.3 7 acC/acT 0 +TYW1B UCSF GRCh37 7 72277868 72277868 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 27 50 0 ENST00000438904.2:c.514G>A p.Val172Ile p.V172I ENST00000438904 172 Gtt/Att 0 +UBA6 UCSF GRCh37 4 68492153 68492153 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 13 96 0 ENST00000322244.5:c.2443C>T p.Pro815Ser p.P815S ENST00000322244 NM_018227.5 815 Cct/Tct 0 +UBA6 UCSF GRCh37 4 68547836 68547836 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 9 54 0 ENST00000322244.5:c.229+1G>A p.X77_splice ENST00000322244 NM_018227.5 0 +UBASH3B UCSF GRCh37 11 122680560 122680560 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 35 62 0 ENST00000284273.5:c.1916G>A p.Gly639Asp p.G639D ENST00000284273 NM_032873.4 639 gGc/gAc 0 +UBE2Q2 UCSF GRCh37 15 76183356 76183356 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 14 104 0 ENST00000267938.4:c.1029+1G>A p.X343_splice ENST00000267938 NM_173469.2 0 +UBFD1 UCSF GRCh37 16 23569458 23569458 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 7 14 0 ENST00000395878.3:c.213C>T p.Val71= p.V71= ENST00000395878 NM_019116.2 71 gtC/gtT 0 +UBOX5 UCSF GRCh37 20 3102359 3102359 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 8 16 0 ENST00000217173.2:c.926G>A p.Gly309Glu p.G309E ENST00000217173 NM_001267584.1 309 gGg/gAg 0 +UBR2 UCSF GRCh37 6 42626058 42626058 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 28 102 0 ENST00000372899.1:c.3063G>A p.Glu1021= p.E1021= ENST00000372899 NM_015255.2 1021 gaG/gaA 0 +UBR4 UCSF GRCh37 1 19453006 19453006 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 17 77 0 ENST00000375254.3:c.9372G>A p.Leu3124= p.L3124= ENST00000375254 NM_020765.2 3124 ttG/ttA 0 +UBR4 UCSF GRCh37 1 19411132 19411132 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 19 29 0 ENST00000375254.3:c.14874C>T p.Ile4958= p.I4958= ENST00000375254 NM_020765.2 4958 atC/atT 0 +UCK1 UCSF GRCh37 9 134400576 134400576 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 14 26 0 ENST00000372215.4:c.685G>A p.Asp229Asn p.D229N ENST00000372215 NM_031432.2 229 Gac/Aac 0 +UCMA UCSF GRCh37 10 13264130 13264130 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 7 21 0 ENST00000378681.3:c.390C>T p.Ser130= p.S130= ENST00000378681 NM_145314.1 130 tcC/tcT 0 +UFD1L UCSF GRCh37 22 19455456 19455456 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 40 81 0 ENST00000263202.10:c.362C>T p.Thr121Ile p.T121I ENST00000263202 NM_005659.6 121 aCc/aTc 0 +UGGT1 UCSF GRCh37 2 128931358 128931358 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 22 51 0 ENST00000259253.6:c.3298G>A p.Asp1100Asn p.D1100N ENST00000259253 NM_020120.3 1100 Gac/Aac 0 +UGT2B4 UCSF GRCh37 4 70352375 70352375 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 119 28 157 0 ENST00000305107.6:c.1042G>A p.Gly348Arg p.G348R ENST00000305107 NM_021139.2 348 Gga/Aga 0 +ULK2 UCSF GRCh37 17 19687113 19687113 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 5 49 0 ENST00000361658.2:c.2357C>T p.Ala786Val p.A786V ENST00000361658 NM_001142610.1 786 gCa/gTa 0 +UNC13B UCSF GRCh37 9 35399159 35399159 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 15 44 0 ENST00000378495.3:c.3829C>T p.Leu1277Phe p.L1277F ENST00000378495 NM_006377.3 1277 Ctc/Ttc 0 +UNC13C UCSF GRCh37 15 54860025 54860025 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 104 18 139 0 ENST00000260323.11:c.5986C>T p.Leu1996= p.L1996= ENST00000260323 NM_001080534.1 1996 Ctg/Ttg 0 +UNC45A UCSF GRCh37 15 91491966 91491966 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 9 0 ENST00000418476.2:c.1820C>T p.Pro607Leu p.P607L ENST00000418476 NM_018671.3 607 cCc/cTc 0 +UNC45A UCSF GRCh37 15 91488139 91488139 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 28 67 0 ENST00000418476.2:c.1045G>A p.Glu349Lys p.E349K ENST00000418476 NM_018671.3 349 Gaa/Aaa 0 +UNC80 UCSF GRCh37 2 210704070 210704070 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 53 15 52 0 ENST00000439458.1:c.3166G>A p.Ala1056Thr p.A1056T ENST00000439458 NM_032504.1 1056 Gcc/Acc 0 +UNC80 UCSF GRCh37 2 210834555 210834555 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 11 44 0 ENST00000439458.1:c.7872G>A p.Arg2624= p.R2624= ENST00000439458 NM_032504.1 2624 agG/agA 0 +UNC93A UCSF GRCh37 6 167711551 167711551 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 7 29 0 ENST00000230256.3:c.618C>T p.Ile206= p.I206= ENST00000230256 NM_018974.3 206 atC/atT 0 +UNC93B1 UCSF GRCh37 11 67765232 67765232 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 3 15 0 ENST00000227471.2:c.819G>A p.Lys273= p.K273= ENST00000227471 NM_030930.2 273 aaG/aaA 0 +UNK UCSF GRCh37 17 73816087 73816087 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 26 29 0 ENST00000589666.1:c.1735C>T p.Pro579Ser p.P579S ENST00000589666 NM_001080419.2 579 Cct/Tct 0 +UNKL UCSF GRCh37 16 1442949 1442949 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 6 10 12 0 ENST00000389221.4:c.957C>T p.Gly319= p.G319= ENST00000389221 NM_001193388.3 319 ggC/ggT 0 +UPK1B UCSF GRCh37 3 118913220 118913220 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 35 78 0 ENST00000264234.3:c.623G>A p.Gly208Asp p.G208D ENST00000264234 NM_006952.3 208 gGc/gAc 0 +URB1 UCSF GRCh37 21 33756656 33756656 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 85 47 108 0 ENST00000382751.3:c.400C>T p.Leu134Phe p.L134F ENST00000382751 NM_014825.2 134 Ctc/Ttc 0 +USH1C UCSF GRCh37 11 17517140 17517140 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 10 37 0 ENST00000318024.4:c.1646+1165G>A *549* ENST00000318024 NM_005709.3 0 +USH2A UCSF GRCh37 1 216011434 216011434 + synonymous_variant Silent SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 49 43 90 0 ENST00000307340.3:c.9270C>T p.Cys3090= p.C3090= ENST00000307340 NM_206933.2 3090 tgC/tgT 0 +USH2A UCSF GRCh37 1 215848193 215848193 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 19 32 0 ENST00000307340.3:c.13060G>A p.Ala4354Thr p.A4354T ENST00000307340 NM_206933.2 4354 Gct/Act 0 +USH2A UCSF GRCh37 1 216262370 216262370 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 37 131 0 ENST00000307340.3:c.4870G>A p.Asp1624Asn p.D1624N ENST00000307340 NM_206933.2 1624 Gat/Aat 0 +USHBP1 UCSF GRCh37 19 17362429 17362429 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 16 33 0 ENST00000252597.3:c.1884G>A p.Gln628= p.Q628= ENST00000252597 NM_031941.3 628 caG/caA 0 +USP16 UCSF GRCh37 21 30411418 30411418 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 32 48 0 ENST00000334352.4:c.804G>A p.Met268Ile p.M268I ENST00000334352 NM_001032410.1 268 atG/atA 0 +USP17L2 UCSF GRCh37 8 11995414 11995414 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 184 27 175 0 ENST00000333796.3:c.856G>A p.Val286Ile p.V286I ENST00000333796 NM_201402.2 286 Gtc/Atc 0 +USP24 UCSF GRCh37 1 55604643 55604643 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 9 74 0 ENST00000294383.6:c.2791G>A p.Ala931Thr p.A931T ENST00000294383 NM_015306.2 931 Gca/Aca 0 +USP31 UCSF GRCh37 16 23080422 23080422 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 12 62 0 ENST00000219689.7:c.3004C>T p.Pro1002Ser p.P1002S ENST00000219689 NM_020718.3 1002 Cca/Tca 0 +USP33 UCSF GRCh37 1 78194332 78194332 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 44 69 0 ENST00000357428.1:c.876G>A p.Met292Ile p.M292I ENST00000357428 292 atG/atA 0 +USP33 UCSF GRCh37 1 78167082 78167082 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 45 86 0 ENST00000357428.1:c.2574G>A p.Trp858Ter p.W858* ENST00000357428 858 tgG/tgA 0 +USP34 UCSF GRCh37 2 61441210 61441210 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 21 51 0 ENST00000398571.2:c.8667C>T p.Ala2889= p.A2889= ENST00000398571 NM_014709.3 2889 gcC/gcT 0 +USP34 UCSF GRCh37 2 61447539 61447539 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 60 106 0 ENST00000398571.2:c.7953C>T p.Pro2651= p.P2651= ENST00000398571 NM_014709.3 2651 ccC/ccT 0 +USP37 UCSF GRCh37 2 219360568 219360568 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 73 17 107 0 ENST00000258399.3:c.1387C>T p.Pro463Ser p.P463S ENST00000258399 NM_020935.2 463 Cca/Tca 0 +USP37 UCSF GRCh37 2 219353081 219353081 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 50 106 0 ENST00000258399.3:c.1536G>A p.Arg512= p.R512= ENST00000258399 NM_020935.2 512 agG/agA 0 +USP40 UCSF GRCh37 2 234429752 234429752 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 51 87 0 ENST00000251722.6:c.2207C>T p.Thr736Ile p.T736I ENST00000251722 736 aCc/aTc 0 +USP42 UCSF GRCh37 7 6155129 6155129 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 116 18 97 0 ENST00000306177.5:c.417G>A p.Met139Ile p.M139I ENST00000306177 NM_032172.2 139 atG/atA 0 +USP7 UCSF GRCh37 16 9002227 9002227 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 14 67 0 ENST00000344836.4:c.1242G>A p.Gln414= p.Q414= ENST00000344836 NM_003470.2 414 caG/caA 0 +VAC14 UCSF GRCh37 16 70806067 70806067 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 32 0 ENST00000261776.5:c.1105G>A p.Asp369Asn p.D369N ENST00000261776 NM_018052.3 369 Gat/Aat 0 +VAV2 UCSF GRCh37 9 136637120 136637120 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 23 44 0 ENST00000371850.3:c.2184G>A p.Trp728Ter p.W728* ENST00000371850 NM_001134398.1 728 tgG/tgA 0 +VCAN UCSF GRCh37 5 82837070 82837070 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 24 76 0 ENST00000265077.3:c.8248G>A p.Glu2750Lys p.E2750K ENST00000265077 NM_004385.4 2750 Gag/Aag 0 +VCAN UCSF GRCh37 5 82815919 82815919 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 57 107 0 ENST00000265077.3:c.1794G>A p.Glu598= p.E598= ENST00000265077 NM_004385.4 598 gaG/gaA 0 +VIL1 UCSF GRCh37 2 219294323 219294323 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 7 22 0 ENST00000248444.5:c.774G>A p.Val258= p.V258= ENST00000248444 NM_007127.2 258 gtG/gtA 0 +VPRBP UCSF GRCh37 3 51466911 51466911 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 38 124 0 ENST00000423656.1:c.192G>A p.Leu64= p.L64= ENST00000423656 64 ttG/ttA 0 +VPS13D UCSF GRCh37 1 12336545 12336545 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 17 61 0 ENST00000358136.3:c.2900G>A p.Gly967Asp p.G967D ENST00000358136 NM_015378.2 967 gGt/gAt 0 +VPS36 UCSF GRCh37 13 53000202 53000202 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 26 73 0 ENST00000378060.4:c.640-1G>A p.X214_splice ENST00000378060 NM_016075.2 0 +VPS52 UCSF GRCh37 6 33234964 33234964 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 17 27 0 ENST00000445902.2:c.1125+1G>A p.X375_splice ENST00000445902 NM_022553.4 0 +VPS53 UCSF GRCh37 17 556631 556631 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 89 21 94 0 ENST00000571805.1:c.508C>T p.Gln170Ter p.Q170* ENST00000571805 170 Caa/Taa 0 +VSTM2A UCSF GRCh37 7 54617556 54617556 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 82 13 90 0 ENST00000407838.3:c.327C>T p.Ser109= p.S109= ENST00000407838 NM_182546.2 109 tcC/tcT 0 +VSX2 UCSF GRCh37 14 74726340 74726340 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 8 29 0 ENST00000261980.2:c.615G>A p.Lys205= p.K205= ENST00000261980 NM_182894.2 205 aaG/aaA 0 +VTCN1 UCSF GRCh37 1 117690383 117690383 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 25 83 0 ENST00000369458.3:c.746G>A p.Ser249Asn p.S249N ENST00000369458 NM_024626.3 249 aGt/aAt 0 +VWA3A UCSF GRCh37 16 22137503 22137503 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 123 63 99 0 ENST00000389398.5:c.1537G>A p.Val513Ile p.V513I ENST00000389398 NM_173615.3 513 Gtt/Att 0 +WARS2 UCSF GRCh37 1 119584944 119584944 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 10 39 0 ENST00000235521.4:c.458G>A p.Gly153Asp p.G153D ENST00000235521 NM_201263.2 153 gGc/gAc 0 +WDFY3 UCSF GRCh37 4 85707170 85707170 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 41 123 0 ENST00000295888.4:c.4024G>A p.Val1342Met p.V1342M ENST00000295888 NM_014991.4 1342 Gtg/Atg 0 +WDFY4 UCSF GRCh37 10 49951403 49951403 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 11 10 0 ENST00000325239.5:c.2269C>T p.Pro757Ser p.P757S ENST00000325239 NM_020945.1 757 Cca/Tca 0 +WDR1 UCSF GRCh37 4 10100664 10100664 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 15 24 0 ENST00000382452.2:c.329G>A p.Trp110Ter p.W110* ENST00000382452 NM_017491.3 110 tGg/tAg 0 +WDR19 UCSF GRCh37 4 39207193 39207193 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 122 20 103 0 ENST00000399820.3:c.727G>A p.Gly243Ser p.G243S ENST00000399820 NM_025132.3 243 Ggc/Agc 0 +WDR19 UCSF GRCh37 4 39236403 39236403 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 106 16 98 0 ENST00000399820.3:c.2271G>A p.Gln757= p.Q757= ENST00000399820 NM_025132.3 757 caG/caA 0 +WDR3 UCSF GRCh37 1 118492674 118492674 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 64 129 0 ENST00000349139.5:c.1667G>A p.Ser556Asn p.S556N ENST00000349139 NM_006784.2 556 aGt/aAt 0 +WDR5 UCSF GRCh37 9 137005076 137005076 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 7 30 0 ENST00000358625.3:c.77G>A p.Ser26Asn p.S26N ENST00000358625 NM_017588.2 26 aGc/aAc 0 +WDR62 UCSF GRCh37 19 36564358 36564358 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 24 13 0 ENST00000270301.7:c.1158G>A p.Trp386Ter p.W386* ENST00000270301 386 tgG/tgA 0 +WDR81 UCSF GRCh37 17 1635993 1635993 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 9 0 ENST00000409644.1:c.4357G>A p.Gly1453Ser p.G1453S ENST00000409644 NM_001163809.1 1453 Ggc/Agc 0 +WDR87 UCSF GRCh37 19 38377201 38377201 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 71 130 0 ENST00000303868.5:c.6993C>T p.Cys2331= p.C2331= ENST00000303868 NM_031951.3 2331 tgC/tgT 0 +WDR93 UCSF GRCh37 15 90258214 90258214 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 14 79 0 ENST00000268130.7:c.644C>T p.Ala215Val p.A215V ENST00000268130 NM_020212.1 215 gCc/gTc 0 +WDR93 UCSF GRCh37 15 90270407 90270407 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 24 61 0 ENST00000268130.7:c.900C>T p.Pro300= p.P300= ENST00000268130 NM_020212.1 300 ccC/ccT 0 +WFDC3 UCSF GRCh37 20 44417682 44417682 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 37 76 0 ENST00000243938.4:c.99C>T p.Cys33= p.C33= ENST00000243938 NM_080614.1 33 tgC/tgT 0 +WHSC1 UCSF GRCh37 4 1902406 1902406 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 48 77 0 ENST00000382891.5:c.25C>T p.Pro9Ser p.P9S ENST00000382891 NM_133335.3 9 Ccc/Tcc 0 +WIPF1 UCSF GRCh37 2 175432672 175432672 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 7 22 0 ENST00000359761.3:c.1259C>T p.Pro420Leu p.P420L ENST00000359761 420 cCt/cTt 0 +WIPF3 UCSF GRCh37 7 29874426 29874426 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 23 49 0 ENST00000242140.5:c.86C>T p.Pro29Leu p.P29L ENST00000242140 29 cCc/cTc 0 +WLS UCSF GRCh37 1 68619204 68619204 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 16 43 0 ENST00000262348.4:c.799G>A p.Glu267Lys p.E267K ENST00000262348 NM_024911.6 267 Gaa/Aaa 0 +WNK3 UCSF GRCh37 X 54319365 54319365 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 4 35 0 ENST00000354646.2:c.1993C>T p.Pro665Ser p.P665S ENST00000354646 NM_020922.4 665 Ccc/Tcc 0 +WNK4 UCSF GRCh37 17 40948172 40948172 + downstream_gene_variant 3'Flank SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 14 45 0 ENST00000328434 NM_001040431.2 0 +WNT2B UCSF GRCh37 1 113010181 113010181 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 4 27 1 ENST00000369686.5:c.22G>T p.Val8Leu p.V8L ENST00000369686 NM_004185.3 8 Gta/Tta 0 +WNT4 UCSF GRCh37 1 22447772 22447772 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 11 23 0 ENST00000290167.6:c.520G>A p.Glu174Lys p.E174K ENST00000290167 NM_030761.4 174 Gag/Aag 0 +WNT5A UCSF GRCh37 3 55513516 55513516 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 219 34 152 0 ENST00000264634.4:c.217G>A p.Ala73Thr p.A73T ENST00000264634 NM_003392.4 73 Gca/Aca 0 +WWC1 UCSF GRCh37 5 167798429 167798429 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 3 17 0 ENST00000265293.4:c.120G>A p.Arg40= p.R40= ENST00000265293 NM_001161662.1 40 agG/agA 0 +WWC2 UCSF GRCh37 4 184205543 184205543 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 17 38 0 ENST00000403733.3:c.3048G>A p.Arg1016= p.R1016= ENST00000403733 NM_024949.5 1016 agG/agA 0 +XAB2 UCSF GRCh37 19 7689302 7689302 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 5 16 0 ENST00000358368.4:c.852G>A p.Arg284= p.R284= ENST00000358368 NM_020196.2 284 cgG/cgA 0 +XIRP1 UCSF GRCh37 3 39229241 39229241 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 7 42 0 ENST00000340369.3:c.1696G>A p.Glu566Lys p.E566K ENST00000340369 NM_194293.2 566 Gag/Aag 0 +XPO6 UCSF GRCh37 16 28192328 28192328 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 25 61 0 ENST00000304658.5:c.28G>A p.Ala10Thr p.A10T ENST00000304658 NM_015171.3 10 Gca/Aca 0 +XPOT UCSF GRCh37 12 64813888 64813888 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 70 12 73 0 ENST00000332707.5:c.528G>A p.Arg176= p.R176= ENST00000332707 NM_007235.4 176 agG/agA 0 +XRCC2 UCSF GRCh37 7 152346419 152346419 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 65 11 82 0 ENST00000359321.1:c.151G>A p.Gly51Arg p.G51R ENST00000359321 NM_005431.1 51 Gga/Aga 0 +XRCC4 UCSF GRCh37 5 82500646 82500646 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 6 37 0 ENST00000338635.6:c.651C>T p.Ile217= p.I217= ENST00000338635 217 atC/atT 0 +YIPF1 UCSF GRCh37 1 54348887 54348887 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 32 76 0 ENST00000072644.1:c.94G>A p.Asp32Asn p.D32N ENST00000072644 NM_018982.4 32 Gat/Aat 0 +YME1L1 UCSF GRCh37 10 27406657 27406657 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 83 25 101 0 ENST00000326799.3:c.1739-1G>A p.X580_splice ENST00000326799 NM_139312.2 0 +YTHDC2 UCSF GRCh37 5 112871458 112871458 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 25 75 0 ENST00000161863.4:c.1065C>T p.Leu355= p.L355= ENST00000161863 NM_022828.3 355 ctC/ctT 0 +YTHDF2 UCSF GRCh37 1 29069935 29069935 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 19 82 0 ENST00000373812.3:c.1153C>T p.Pro385Ser p.P385S ENST00000373812 NM_016258.2 385 Ccc/Tcc 0 +ZAN UCSF GRCh37 7 100350516 100350516 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 9 33 0 ENST00000546292.1:c.2788C>T p.Pro930Ser p.P930S ENST00000546292 NM_173059.1 930 Ccc/Tcc 0 +ZBTB1 UCSF GRCh37 14 64989761 64989761 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 130 63 162 0 ENST00000554015.1:c.1539C>T p.Asp513= p.D513= ENST00000554015 513 gaC/gaT 0 +ZBTB10 UCSF GRCh37 8 81412055 81412055 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 174 35 180 0 ENST00000430430.1:c.1299C>T p.Ser433= p.S433= ENST00000430430 433 agC/agT 0 +ZC3H12A UCSF GRCh37 1 37945949 37945949 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 15 16 0 ENST00000373087.6:c.502C>T p.Leu168= p.L168= ENST00000373087 NM_025079.2 168 Ctg/Ttg 0 +ZC3H4 UCSF GRCh37 19 47588394 47588394 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 49 0 ENST00000253048.5:c.1026C>T p.Gly342= p.G342= ENST00000253048 NM_015168.1 342 ggC/ggT 0 +ZCCHC12 UCSF GRCh37 X 117959756 117959756 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 37 52 0 ENST00000310164.2:c.549G>A p.Glu183= p.E183= ENST00000310164 NM_173798.2 183 gaG/gaA 0 +ZCCHC6 UCSF GRCh37 9 88903610 88903610 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 6 32 0 ENST00000375963.3:c.4470G>A p.Arg1490= p.R1490= ENST00000375963 NM_001185059.1 1490 agG/agA 0 +ZDBF2 UCSF GRCh37 2 207175568 207175568 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 82 66 134 0 ENST00000374423.3:c.6316C>T p.Pro2106Ser p.P2106S ENST00000374423 NM_020923.1 2106 Cct/Tct 0 +ZFHX2 UCSF GRCh37 14 24003498 24003498 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 5 31 0 ENST00000419474.3:c.1037C>T p.Pro346Leu p.P346L ENST00000419474 NM_033400.2 346 cCc/cTc 0 +ZFHX2 UCSF GRCh37 14 24002867 24002867 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 25 61 0 ENST00000419474.3:c.1668C>T p.Pro556= p.P556= ENST00000419474 NM_033400.2 556 ccC/ccT 0 +ZFHX4 UCSF GRCh37 8 77764123 77764123 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 130 27 153 0 ENST00000521891.2:c.4966G>A p.Ala1656Thr p.A1656T ENST00000521891 NM_024721.4 1656 Gca/Aca 0 +ZFYVE16 UCSF GRCh37 5 79734594 79734594 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 18 78 0 ENST00000338008.5:c.2090C>T p.Pro697Leu p.P697L ENST00000338008 NM_014733.3 697 cCa/cTa 0 +ZFYVE16 UCSF GRCh37 5 79752881 79752881 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 82 0 ENST00000338008.5:c.3913G>A p.Ala1305Thr p.A1305T ENST00000338008 NM_014733.3 1305 Gcc/Acc 0 +ZFYVE28 UCSF GRCh37 4 2306889 2306889 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 8 18 0 ENST00000290974.2:c.1178G>A p.Gly393Asp p.G393D ENST00000290974 NM_020972.2 393 gGc/gAc 0 +ZFYVE28 UCSF GRCh37 4 2306375 2306375 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0012 P01_Rec Untested WXS Illumina HiSeq 5 12 8 0 ENST00000290974.2:c.1692C>T p.Cys564= p.C564= ENST00000290974 NM_020972.2 564 tgC/tgT 0 +ZIM3 UCSF GRCh37 19 57647316 57647316 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 20 123 0 ENST00000269834.1:c.389G>A p.Gly130Asp p.G130D ENST00000269834 NM_052882.1 130 gGc/gAc 0 +ZKSCAN3 UCSF GRCh37 6 28333633 28333633 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 96 39 60 0 ENST00000252211.2:c.1188G>A p.Lys396= p.K396= ENST00000252211 NM_024493.3 396 aaG/aaA 0 +ZKSCAN5 UCSF GRCh37 7 99129352 99129352 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 43 67 0 ENST00000326775.5:c.2000G>A p.Gly667Glu p.G667E ENST00000326775 NM_145102.2 667 gGg/gAg 0 +ZMYM4 UCSF GRCh37 1 35873697 35873697 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 89 35 82 0 ENST00000314607.6:c.3885G>A p.Arg1295= p.R1295= ENST00000314607 NM_005095.2 1295 cgG/cgA 0 +ZNF17 UCSF GRCh37 19 57932525 57932525 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 17 118 0 ENST00000601808.1:c.1665G>A p.Glu555= p.E555= ENST00000601808 NM_006959.2 555 gaG/gaA 0 +ZNF211 UCSF GRCh37 19 58152405 58152405 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 24 41 0 ENST00000347302.3:c.551C>T p.Pro184Leu p.P184L ENST00000347302 NM_198855.2 184 cCc/cTc 0 +ZNF224 UCSF GRCh37 19 44605305 44605305 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 46 78 0 ENST00000336976.6:c.162G>A p.Arg54= p.R54= ENST00000336976 NM_013398.2 54 agG/agA 0 +ZNF226 UCSF GRCh37 19 44681435 44681435 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 152 18 125 0 ENST00000337433.5:c.2020G>A p.Asp674Asn p.D674N ENST00000337433 NM_001032373.1 674 Gat/Aat 0 +ZNF25 UCSF GRCh37 10 38241328 38241328 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 87 48 116 1 ENST00000302609.7:c.1098G>A p.Gly366= p.G366= ENST00000302609 NM_145011.2 366 ggG/ggA 0 +ZNF273 UCSF GRCh37 7 64377994 64377994 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 113 95 185 0 ENST00000476120.1:c.138C>T p.Phe46= p.F46= ENST00000476120 NM_021148.2 46 ttC/ttT 0 +ZNF275 UCSF GRCh37 X 152612560 152612560 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 17 0 ENST00000370251.3:c.417G>A p.Arg139= p.R139= ENST00000370251 NM_001080485.3 139 agG/agA 0 +ZNF28 UCSF GRCh37 19 53302984 53302984 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 24 86 163 0 ENST00000457749.2:c.2114A>G p.Asn705Ser p.N705S ENST00000457749 NM_006969.3 705 aAc/aGc 0 +ZNF282 UCSF GRCh37 7 148910902 148910902 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 6 10 0 ENST00000262085.3:c.1176C>T p.Gly392= p.G392= ENST00000262085 NM_003575.2 392 ggC/ggT 0 +ZNF286B UCSF GRCh37 17 18565329 18565329 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 18 92 0 ENST00000545289.1:c.1490G>A p.Cys497Tyr p.C497Y ENST00000545289 NM_001145045.1 497 tGt/tAt 0 +ZNF292 UCSF GRCh37 6 87967271 87967271 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 44 124 0 ENST00000369577.3:c.3924C>T p.Ser1308= p.S1308= ENST00000369577 NM_015021.1 1308 tcC/tcT 0 +ZNF311 UCSF GRCh37 6 28966515 28966515 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 30 69 0 ENST00000377179.3:c.411C>T p.Tyr137= p.Y137= ENST00000377179 NM_001010877.2 137 taC/taT 0 +ZNF341 UCSF GRCh37 20 32354790 32354790 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 14 84 0 ENST00000375200.1:c.1356C>T p.Ser452= p.S452= ENST00000375200 NM_001282933.1 452 agC/agT 0 +ZNF354A UCSF GRCh37 5 178152397 178152397 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 24 68 0 ENST00000335815.2:c.236G>A p.Gly79Asp p.G79D ENST00000335815 NM_005649.2 79 gGt/gAt 0 +ZNF354C UCSF GRCh37 5 178505788 178505788 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 47 91 0 ENST00000315475.6:c.355C>T p.His119Tyr p.H119Y ENST00000315475 NM_014594.1 119 Cac/Tac 0 +ZNF385B UCSF GRCh37 2 180634269 180634269 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 4 22 0 ENST00000410066.1:c.214C>T p.Pro72Ser p.P72S ENST00000410066 NM_152520.4 72 Cca/Tca 0 +ZNF410 UCSF GRCh37 14 74376048 74376048 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 49 109 0 ENST00000555044.1:c.918G>A p.Glu306= p.E306= ENST00000555044 NM_021188.2 306 gaG/gaA 0 +ZNF425 UCSF GRCh37 7 148802315 148802315 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 23 38 0 ENST00000378061.2:c.648G>A p.Gln216= p.Q216= ENST00000378061 NM_001001661.2 216 caG/caA 0 +ZNF441 UCSF GRCh37 19 11891835 11891835 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 47 119 0 ENST00000357901.4:c.1196C>T p.Ala399Val p.A399V ENST00000357901 NM_152355.2 399 gCc/gTc 0 +ZNF451 UCSF GRCh37 6 57013222 57013222 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 12 57 0 ENST00000370706.4:c.2339G>A p.Ser780Asn p.S780N ENST00000370706 NM_001031623.2 780 aGt/aAt 0 +ZNF462 UCSF GRCh37 9 109687573 109687573 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 132 21 90 0 ENST00000277225.5:c.1380C>T p.Asn460= p.N460= ENST00000277225 460 aaC/aaT 0 +ZNF483 UCSF GRCh37 9 114304193 114304193 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 241 27 151 0 ENST00000309235.5:c.978G>A p.Arg326= p.R326= ENST00000309235 NM_133464.2 326 agG/agA 0 +ZNF493 UCSF GRCh37 19 21606767 21606767 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 57 122 0 ENST00000355504.4:c.922G>A p.Glu308Lys p.E308K ENST00000355504 NM_175910.6 308 Gaa/Aaa 0 +ZNF506 UCSF GRCh37 19 19916846 19916846 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 114 13 129 0 ENST00000443905.2:c.220C>T p.Pro74Ser p.P74S ENST00000443905 74 Ccc/Tcc 0 +ZNF507 UCSF GRCh37 19 32845510 32845510 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 22 81 0 ENST00000311921.4:c.1774G>A p.Glu592Lys p.E592K ENST00000311921 NM_014910.4 592 Gaa/Aaa 0 +ZNF518B UCSF GRCh37 4 10446731 10446731 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 129 91 188 0 ENST00000326756.3:c.1222G>A p.Val408Ile p.V408I ENST00000326756 NM_053042.2 408 Gtt/Att 0 +ZNF518B UCSF GRCh37 4 10445799 10445799 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 131 28 84 0 ENST00000326756.3:c.2154C>T p.Gly718= p.G718= ENST00000326756 NM_053042.2 718 ggC/ggT 0 +ZNF546 UCSF GRCh37 19 40520361 40520361 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 14 83 0 ENST00000347077.4:c.1184G>A p.Ser395Asn p.S395N ENST00000347077 NM_178544.3 395 aGt/aAt 0 +ZNF549 UCSF GRCh37 19 58049092 58049092 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 61 136 0 ENST00000376233.3:c.720C>T p.Val240= p.V240= ENST00000376233 NM_001199295.1 240 gtC/gtT 0 +ZNF555 UCSF GRCh37 19 2850645 2850645 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 57 97 0 ENST00000334241.4:c.64G>A p.Asp22Asn p.D22N ENST00000334241 NM_152791.4 22 Gat/Aat 0 +ZNF570 UCSF GRCh37 19 37975761 37975761 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 127 20 117 0 ENST00000330173.1:c.1237C>T p.Pro413Ser p.P413S ENST00000330173 NM_144694.1 413 Cct/Tct 0 +ZNF574 UCSF GRCh37 19 42582801 42582801 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 16 63 0 ENST00000359044.4:c.43C>T p.Arg15Cys p.R15C ENST00000359044 NM_022752.5 15 Cgc/Tgc 0 +ZNF598 UCSF GRCh37 16 2048796 2048796 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.086,1000g2011may_all_0.1651,snp132_rs1058474 P01_Rec Untested WXS Illumina HiSeq 9 5 8 0 ENST00000431526.1:c.2268G>A p.Arg756= p.R756= ENST00000431526 756 agG/agA 0 +ZNF609 UCSF GRCh37 15 64972457 64972457 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 13 29 0 ENST00000326648.3:c.3843G>A p.Lys1281= p.K1281= ENST00000326648 NM_015042.1 1281 aaG/aaA 0 +ZNF616 UCSF GRCh37 19 52620039 52620039 + missense_variant Missense_Mutation SNP A A C NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 11 87 150 0 ENST00000600228.1:c.378T>G p.His126Gln p.H126Q ENST00000600228 NM_178523.3 126 caT/caG 0 +ZNF638 UCSF GRCh37 2 71654398 71654398 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 68 80 138 0 ENST00000264447.4:c.5399A>G p.Asp1800Gly p.D1800G ENST00000264447 NM_001014972.2 1800 gAc/gGc 0 +ZNF645 UCSF GRCh37 X 22291335 22291335 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P01_Rec Untested WXS Illumina HiSeq 19 0 ENST00000323684.1:c.227del p.Ala76ValfsTer26 p.A76Vfs*26 ENST00000323684 NM_152577.3 76 gCt/gt 0 +ZNF646 UCSF GRCh37 16 31089358 31089358 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 18 34 0 ENST00000394979.2:c.1713G>A p.Lys571= p.K571= ENST00000394979 571 aaG/aaA 0 +ZNF658 UCSF GRCh37 9 40773337 40773337 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.145,1000g2011may_all_0.2772,snp132_rs72624049 P01_Rec Untested WXS Illumina HiSeq 142 25 195 0 ENST00000602553.1:c.1938G>A p.Lys646= p.K646= ENST00000602553 646 aaG/aaA 0 +ZNF665 UCSF GRCh37 19 53669476 53669476 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 55 120 0 ENST00000600412.1:c.72G>A p.Gln24= p.Q24= ENST00000600412 24 caG/caA 0 +ZNF671 UCSF GRCh37 19 58232498 58232498 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 54 117 0 ENST00000317398.6:c.956G>A p.Gly319Glu p.G319E ENST00000317398 NM_024833.2 319 gGg/gAg 0 +ZNF680 UCSF GRCh37 7 63981939 63981939 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 128 21 125 0 ENST00000309683.6:c.1193G>A p.Arg398Lys p.R398K ENST00000309683 NM_178558.4 398 aGa/aAa 0 +ZNF687 UCSF GRCh37 1 151259011 151259011 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 5 46 0 ENST00000324048.5:c.244G>A p.Val82Ile p.V82I ENST00000324048 82 Gtc/Atc 0 +ZNF750 UCSF GRCh37 17 80790041 80790041 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 10 87 0 ENST00000269394.3:c.290C>T p.Ala97Val p.A97V ENST00000269394 NM_024702.2 97 gCc/gTc 0 +ZNF773 UCSF GRCh37 19 58017913 58017913 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 6 56 0 ENST00000282292.4:c.450G>A p.Arg150= p.R150= ENST00000282292 NM_198542.1 150 agG/agA 0 +ZNF789 UCSF GRCh37 7 99074104 99074104 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 3 15 0 ENST00000331410.5:c.24+1G>A p.X8_splice ENST00000331410 NM_213603.2 0 +ZNF804A UCSF GRCh37 2 185800689 185800689 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 10 90 0 ENST00000302277.6:c.566G>A p.Ser189Asn p.S189N ENST00000302277 NM_194250.1 189 aGt/aAt 0 +ZNF81 UCSF GRCh37 X 47755295 47755295 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 3 11 0 ENST00000338637.7:c.233G>A p.Gly78Glu p.G78E ENST00000338637 NM_007137.3 78 gGg/gAg 0 +ZNF90 UCSF GRCh37 19 20229997 20229997 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 102 49 114 0 ENST00000418063.2:c.1634C>T p.Ala545Val p.A545V ENST00000418063 NM_007138.1 545 gCc/gTc 0 +ZNF90 UCSF GRCh37 19 20228589 20228589 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 59 32 117 0 ENST00000418063.2:c.227-1G>A p.X76_splice ENST00000418063 NM_007138.1 0 +ZNFX1 UCSF GRCh37 20 47865631 47865631 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 7 45 0 ENST00000371752.1:c.3930C>T p.Asp1310= p.D1310= ENST00000371752 1310 gaC/gaT 0 +ZNRF3 UCSF GRCh37 22 29446120 29446120 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 15 24 0 ENST00000544604.2:c.1951G>A p.Ala651Thr p.A651T ENST00000544604 NM_001206998.1 651 Gcc/Acc 0 +ZNRF4 UCSF GRCh37 19 5455737 5455737 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 4 18 0 ENST00000222033.4:c.235G>A p.Ala79Thr p.A79T ENST00000222033 NM_181710.3 79 Gcc/Acc 0 +ZWILCH UCSF GRCh37 15 66806367 66806367 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 65 10 59 0 ENST00000307897.5:c.147C>T p.Asn49= p.N49= ENST00000307897 NM_017975.3 49 aaC/aaT 0 +ZZEF1 UCSF GRCh37 17 3999274 3999274 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 6 52 0 ENST00000381638.2:c.1765-1G>A p.X589_splice ENST00000381638 NM_015113.3 0 +ANKRA2 UCSF GRCh37 5 72858699 72858699 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Pri Untested WXS Illumina HiSeq 70 8 89 0 ENST00000296785.3:c.8C>A p.Thr3Lys p.T3K ENST00000296785 NM_023039.4 3 aCa/aAa 0 +ARID1A UCSF GRCh37 1 27106658 27106658 + missense_variant Missense_Mutation SNP A A G NOVEL P02_Pri somatic WXS Sanger Illumina HiSeq 34 13 97 0 ENST00000324856.7:c.6269A>G p.His2090Arg p.H2090R ENST00000324856 NM_006015.4 2090 cAc/cGc 0 +C7orf70 UCSF GRCh37 7 6370158 6370158 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 114 18 195 1 ENST00000313324.4:c.628C>T p.Arg210Cys p.R210C ENST00000313324 NM_001037163.1 210 Cgc/Tgc 0 +CCDC168 UCSF GRCh37 13 103381996 103381996 + frameshift_variant Frame_Shift_Del DEL A A - snp132_rs34874700 P02_Pri Untested WXS Illumina HiSeq 6 0 ENST00000322527.2:c.7164delT p.Phe2388LeufsTer25 p.F2388Lfs*25 ENST00000322527 NM_001146197.1 2388 ttT/tt 0 +CYLC2 UCSF GRCh37 9 105767104 105767104 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 27 21 45 0 ENST00000374798.3:c.308G>A p.Arg103His p.R103H ENST00000374798 NM_001340.3 103 cGt/cAt 0 +E2F8 UCSF GRCh37 11 19252368 19252368 + synonymous_variant Silent SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 36 20 48 0 ENST00000250024.4:c.1080C>T p.Val360= p.V360= ENST00000250024 NM_024680.3 360 gtC/gtT 0 +EPS8L3 UCSF GRCh37 1 110293388 110293388 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.0085 P02_Pri Untested WXS Illumina HiSeq 8 6 17 0 ENST00000361965.4:c.1664C>T p.Thr555Met p.T555M ENST00000361965 555 aCg/aTg 0 +FAM149A UCSF GRCh37 4 187084645 187084645 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 21 6 36 0 ENST00000356371.5:c.1774G>A p.Gly592Arg p.G592R ENST00000356371 592 Gga/Aga 0 +FAM171A1 UCSF GRCh37 10 15296788 15296788 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 19 12 55 0 ENST00000378116.4:c.509C>T p.Thr170Met p.T170M ENST00000378116 NM_001010924.1 170 aCg/aTg 0 +GATA6 UCSF GRCh37 18 19761487 19761487 + missense_variant Missense_Mutation SNP C C A NOVEL P02_Pri Untested WXS Illumina HiSeq 35 5 52 0 ENST00000269216.3:c.1376C>A p.Ala459Asp p.A459D ENST00000269216 NM_005257.4 459 gCc/gAc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Pri Untested WXS Illumina HiSeq 29 35 77 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LAMB3 UCSF GRCh37 1 209805972 209805972 + missense_variant Missense_Mutation SNP C C T snp132_rs113063967 P02_Pri Untested WXS Illumina HiSeq 15 7 19 0 ENST00000356082.4:c.778G>A p.Ala260Thr p.A260T ENST00000356082 NM_000228.2 260 Gca/Aca 0 +LRRC37A3 UCSF GRCh37 17 62856876 62856876 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.005,1000g2011may_all_0.0139,snp132_rs77916588 P02_Pri Untested WXS Illumina HiSeq 125 43 218 0 ENST00000319651.5:c.3388G>A p.Val1130Ile p.V1130I ENST00000319651 1130 Gtt/Att 0 +NEURL UCSF GRCh37 10 105349981 105349981 + missense_variant Missense_Mutation SNP A A C NOVEL P02_Pri Untested WXS Illumina HiSeq 15 13 47 0 ENST00000369780.4:c.1577A>C p.Glu526Ala p.E526A ENST00000369780 NM_004210.4 526 gAa/gCa 0 +OGT UCSF GRCh37 X 70787552 70787552 + missense_variant Missense_Mutation SNP C C A NOVEL P02_Pri Untested WXS Illumina HiSeq 12 12 60 0 ENST00000373719.3:c.2792C>A p.Thr931Asn p.T931N ENST00000373719 NM_181673.2 931 aCc/aAc 0 +RBBP7 UCSF GRCh37 X 16881197 16881197 + missense_variant Missense_Mutation SNP T T A NOVEL P02_Pri Untested WXS Illumina HiSeq 37 29 85 0 ENST00000380087.2:c.188A>T p.His63Leu p.H63L ENST00000380087 63 cAt/cTt 0 +RHPN2 UCSF GRCh37 19 33490566 33490566 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.110,snp132_rs74582927 P02_Pri Untested WXS Illumina HiSeq 21 5 35 0 ENST00000254260.3:c.1151A>G p.Gln384Arg p.Q384R ENST00000254260 NM_033103.4 384 cAg/cGg 0 +SERPINB12 UCSF GRCh37 18 61228397 61228397 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Pri Untested WXS Illumina HiSeq 75 26 104 0 ENST00000269491.1:c.464G>T p.Arg155Ile p.R155I ENST00000269491 NM_080474.1 155 aGa/aTa 0 +SLC39A12 UCSF GRCh37 10 18250713 18250713 + synonymous_variant Silent SNP T T C NOVEL P02_Pri Untested WXS Illumina HiSeq 58 19 94 0 ENST00000377369.2:c.465T>C p.Asp155= p.D155= ENST00000377369 NM_001145195.1 155 gaT/gaC 0 +SNCAIP UCSF GRCh37 5 121787259 121787259 + missense_variant Missense_Mutation SNP A A C NOVEL P02_Pri Untested WXS Illumina HiSeq 47 14 96 0 ENST00000261368.8:c.2717A>C p.Asn906Thr p.N906T ENST00000261368 NM_005460.2 906 aAc/aCc 0 +SPIC UCSF GRCh37 12 101880272 101880272 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Pri Untested WXS Illumina HiSeq 100 35 131 0 ENST00000551346.1:c.470G>T p.Arg157Ile p.R157I ENST00000551346 157 aGa/aTa 0 +TP53 UCSF GRCh37 17 7578370 7578370 + splice_donor_variant Splice_Site SNP C C T NOVEL P02_Pri somatic WXS Sanger Illumina HiSeq 2 14 21 0 ENST00000269305.4:c.559+1G>A p.X187_splice ENST00000269305 NM_001126112.2 0 +TPTE2 UCSF GRCh37 13 20006639 20006639 + missense_variant Missense_Mutation SNP T T A NOVEL P02_Pri Untested WXS Illumina HiSeq 96 12 90 1 ENST00000400230.2:c.1196A>T p.Lys399Ile p.K399I ENST00000400230 399 aAa/aTa 0 +TRAPPC10 UCSF GRCh37 21 45502963 45502963 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Pri Untested WXS Illumina HiSeq 35 27 92 0 ENST00000291574.4:c.2018C>T p.Ala673Val p.A673V ENST00000291574 NM_003274.4 673 gCg/gTg 0 +ZNF521 UCSF GRCh37 18 22804622 22804622 + missense_variant Missense_Mutation SNP C C G NOVEL P02_Pri Untested WXS Illumina HiSeq 43 5 69 1 ENST00000361524.3:c.3260G>C p.Gly1087Ala p.G1087A ENST00000361524 NM_015461.2 1087 gGc/gCc 0 +ZNF676 UCSF GRCh37 19 22364067 22364090 + inframe_deletion In_Frame_Del DEL CAAAATGATCTGACATATTCTTTA CAAAATGATCTGACATATTCTTTA - NOVEL P02_Pri Untested WXS Illumina HiSeq 6 0 ENST00000397121.2:c.429_452del p.Lys144_Cys151del p.K144_C151del ENST00000397121 NM_001001411.2 143 tgTAAAGAATATGTCAGATCATTTTGc/tgc 0 +ARID1A UCSF GRCh37 1 27106658 27106658 + missense_variant Missense_Mutation SNP A A G NOVEL P02_Rec somatic WXS Sanger Illumina HiSeq 87 13 97 0 ENST00000324856.7:c.6269A>G p.His2090Arg p.H2090R ENST00000324856 NM_006015.4 2090 cAc/cGc 0 +CEP350 UCSF GRCh37 1 180022947 180022948 + frameshift_variant Frame_Shift_Ins INS - - TCGACAGTATATGAAAGAGGAAGAAA NOVEL P02_Rec Untested WXS Illumina HiSeq 11 0 ENST00000367607.3:c.5052_5053insTCGACAGTATATGAAAGAGGAAGAAA p.Arg1685SerfsTer13 p.R1685Sfs*13 ENST00000367607 NM_014810.4 1684 -/TCGACAGTATATGAAAGAGGAAGAAA 0 +CYLC2 UCSF GRCh37 9 105767104 105767104 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 35 34 45 0 ENST00000374798.3:c.308G>A p.Arg103His p.R103H ENST00000374798 NM_001340.3 103 cGt/cAt 0 +E2F8 UCSF GRCh37 11 19252368 19252368 + synonymous_variant Silent SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 36 21 48 0 ENST00000250024.4:c.1080C>T p.Val360= p.V360= ENST00000250024 NM_024680.3 360 gtC/gtT 0 +EPS8L3 UCSF GRCh37 1 110293388 110293388 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.0085 P02_Rec Untested WXS Illumina HiSeq 23 20 17 0 ENST00000361965.4:c.1664C>T p.Thr555Met p.T555M ENST00000361965 555 aCg/aTg 0 +FAM171A1 UCSF GRCh37 10 15296788 15296788 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 41 15 55 0 ENST00000378116.4:c.509C>T p.Thr170Met p.T170M ENST00000378116 NM_001010924.1 170 aCg/aTg 0 +FCGBP UCSF GRCh37 19 40368330 40368330 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.124,1000g2011may_all_0.2035,snp132_rs74540349 P02_Rec Untested WXS Illumina HiSeq 72 8 47 1 ENST00000221347.6:c.13018G>A p.Glu4340Lys p.E4340K ENST00000221347 NM_003890.2 4340 Gaa/Aaa 0 +GGT1 UCSF GRCh37 22 25011077 25011077 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 19 4 24 0 ENST00000248923.4:c.365C>T p.Ser122Leu p.S122L ENST00000248923 NM_013430.2 122 tCg/tTg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 55 40 77 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LAMB3 UCSF GRCh37 1 209805972 209805972 + missense_variant Missense_Mutation SNP C C T snp132_rs113063967 P02_Rec Untested WXS Illumina HiSeq 18 8 19 0 ENST00000356082.4:c.778G>A p.Ala260Thr p.A260T ENST00000356082 NM_000228.2 260 Gca/Aca 0 +LRP4 UCSF GRCh37 11 46898772 46898772 + synonymous_variant Silent SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 70 11 70 0 ENST00000378623.1:c.3255C>T p.Ala1085= p.A1085= ENST00000378623 NM_002334.3 1085 gcC/gcT 0 +LRRC37A3 UCSF GRCh37 17 62856876 62856876 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.005,1000g2011may_all_0.0139,snp132_rs77916588 P02_Rec Untested WXS Illumina HiSeq 206 29 218 0 ENST00000319651.5:c.3388G>A p.Val1130Ile p.V1130I ENST00000319651 1130 Gtt/Att 0 +MMRN1 UCSF GRCh37 4 90874492 90874492 + stop_gained Nonsense_Mutation SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 85 16 103 0 ENST00000264790.2:c.3610C>T p.Arg1204Ter p.R1204* ENST00000264790 NM_007351.2 1204 Cga/Tga 0 +NEURL UCSF GRCh37 10 105349981 105349981 + missense_variant Missense_Mutation SNP A A C NOVEL P02_Rec Untested WXS Illumina HiSeq 35 17 47 0 ENST00000369780.4:c.1577A>C p.Glu526Ala p.E526A ENST00000369780 NM_004210.4 526 gAa/gCa 0 +NPC1L1 UCSF GRCh37 7 44578793 44578793 + synonymous_variant Silent SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 79 9 79 0 ENST00000289547.4:c.1203C>T p.Phe401= p.F401= ENST00000289547 NM_013389.2 401 ttC/ttT 0 +OGT UCSF GRCh37 X 70787552 70787552 + missense_variant Missense_Mutation SNP C C A NOVEL P02_Rec Untested WXS Illumina HiSeq 21 12 60 0 ENST00000373719.3:c.2792C>A p.Thr931Asn p.T931N ENST00000373719 NM_181673.2 931 aCc/aAc 0 +PTPRM UCSF GRCh37 18 8244164 8244164 + synonymous_variant Silent SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 103 14 85 0 ENST00000332175.8:c.2409C>T p.Asp803= p.D803= ENST00000332175 NM_002845.3 803 gaC/gaT 0 +RBBP7 UCSF GRCh37 X 16881197 16881197 + missense_variant Missense_Mutation SNP T T A NOVEL P02_Rec Untested WXS Illumina HiSeq 82 38 85 0 ENST00000380087.2:c.188A>T p.His63Leu p.H63L ENST00000380087 63 cAt/cTt 0 +SERPINB12 UCSF GRCh37 18 61228397 61228397 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Rec Untested WXS Illumina HiSeq 67 50 104 0 ENST00000269491.1:c.464G>T p.Arg155Ile p.R155I ENST00000269491 NM_080474.1 155 aGa/aTa 0 +SLC39A12 UCSF GRCh37 10 18250713 18250713 + synonymous_variant Silent SNP T T C NOVEL P02_Rec Untested WXS Illumina HiSeq 70 44 94 0 ENST00000377369.2:c.465T>C p.Asp155= p.D155= ENST00000377369 NM_001145195.1 155 gaT/gaC 0 +SPIC UCSF GRCh37 12 101880272 101880272 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Rec Untested WXS Illumina HiSeq 72 58 131 0 ENST00000551346.1:c.470G>T p.Arg157Ile p.R157I ENST00000551346 157 aGa/aTa 0 +TP53 UCSF GRCh37 17 7578370 7578370 + splice_donor_variant Splice_Site SNP C C T NOVEL P02_Rec somatic WXS Sanger Illumina HiSeq 4 39 21 0 ENST00000269305.4:c.559+1G>A p.X187_splice ENST00000269305 NM_001126112.2 0 +TRAPPC10 UCSF GRCh37 21 45502963 45502963 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 45 45 92 0 ENST00000291574.4:c.2018C>T p.Ala673Val p.A673V ENST00000291574 NM_003274.4 673 gCg/gTg 0 +WDR33 UCSF GRCh37 2 128463940 128463940 + missense_variant Missense_Mutation SNP G G C NOVEL P02_Rec Untested WXS Illumina HiSeq 107 15 101 0 ENST00000322313.4:c.3968C>G p.Pro1323Arg p.P1323R ENST00000322313 NM_018383.4 1323 cCg/cGg 0 +ZNF676 UCSF GRCh37 19 22364067 22364090 + inframe_deletion In_Frame_Del DEL CAAAATGATCTGACATATTCTTTA CAAAATGATCTGACATATTCTTTA - NOVEL P02_Rec Untested WXS Illumina HiSeq 9 0 ENST00000397121.2:c.429_452del p.Lys144_Cys151del p.K144_C151del ENST00000397121 NM_001001411.2 143 tgTAAAGAATATGTCAGATCATTTTGc/tgc 0 +ZNF676 UCSF GRCh37 19 22364102 22364146 + inframe_deletion In_Frame_Del DEL TTTCTCTCCAGTATGCCTTATCTTATGTCTGTTTGAATTTGAACA TTTCTCTCCAGTATGCCTTATCTTATGTCTGTTTGAATTTGAACA - NOVEL P02_Rec Untested WXS Illumina HiSeq 7 0 ENST00000397121.2:c.373_417del p.Cys125_Lys139del p.C125_K139del ENST00000397121 NM_001001411.2 125 TGTTCAAATTCAAACAGACATAAGATAAGGCATACTGGAGAGAAA/- 0 +ACSF2 UCSF GRCh37 17 48541208 48541208 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Pri Untested WXS Illumina HiSeq 66 31 102 0 ENST00000300441.4:c.1076T>G p.Met359Arg p.M359R ENST00000300441 NM_025149.4 359 aTg/aGg 0 +BOD1L UCSF GRCh37 4 13604659 13604659 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Pri Untested WXS Illumina HiSeq 139 76 170 0 ENST00000040738.5:c.3865G>A p.Val1289Ile p.V1289I ENST00000040738 NM_148894.2 1289 Gtt/Att 0 +CAND2 UCSF GRCh37 3 12858462 12858462 + synonymous_variant Silent SNP C C T NOVEL P04_Pri somatic WXS Sanger Illumina HiSeq 33 25 61 1 ENST00000456430.2:c.2031C>T p.Asp677= p.D677= ENST00000456430 NM_001162499.1 677 gaC/gaT 0 +CDH7 UCSF GRCh37 18 63481815 63481815 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.013,1000g2011may_all_0.0353,snp132_rs17075245 P04_Pri Untested WXS Illumina HiSeq 110 54 141 0 ENST00000323011.3:c.600G>A p.Pro200= p.P200= ENST00000323011 NM_033646.1 200 ccG/ccA 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Pri Untested WXS Illumina HiSeq 75 46 91 0 ENST00000345146.2:c.394C>T p.Arg132Cys p.R132C ENST00000345146 NM_005896.2 132 Cgt/Tgt 0 +MUC4 UCSF GRCh37 3 195506723 195506770 + inframe_deletion In_Frame_Del DEL TGTCGGTGACAGGAAGAGGGGTGGCGTGACGTGTGGATGCTGAGGAAG TGTCGGTGACAGGAAGAGGGGTGGCGTGACGTGTGGATGCTGAGGAAG - NOVEL P04_Pri Untested WXS Illumina HiSeq 8 0 ENST00000463781.3:c.11691_11738del p.Arg3900_Thr3915del p.R3900_T3915del ENST00000463781 NM_018406.6 3894 aCTTCCTCAGCATCCACACGTCACGCCACCCCTCTTCCTGTCACCGACAct/act 0 +OR10V1 UCSF GRCh37 11 59480502 59480502 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Pri Untested WXS Illumina HiSeq 83 44 124 0 ENST00000307552.2:c.817C>T p.Arg273Trp p.R273W ENST00000307552 NM_001005324.1 273 Cgg/Tgg 0 +PSAPL1 UCSF GRCh37 4 7435803 7435803 + synonymous_variant Silent SNP G G A NOVEL P04_Pri somatic WXS Sanger Illumina HiSeq 101 42 122 0 ENST00000319098.4:c.804C>T p.Ala268= p.A268= ENST00000319098 NM_001085382.1 268 gcC/gcT 0 +RYR1 UCSF GRCh37 19 38939100 38939100 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.005,1000g2011may_all_0.0263 P04_Pri somatic WXS Sanger Illumina HiSeq 111 67 128 0 ENST00000359596.3:c.906C>T p.Asp302= p.D302= ENST00000359596 302 gaC/gaT 0 +SGK223 UCSF GRCh37 8 8234869 8234870 + inframe_insertion In_Frame_Ins INS - - GCCGCT snp132_rs35972623 P04_Pri Untested WXS Illumina HiSeq 7 0 ENST00000520004.1:c.1049_1050insAGCGGC p.Ala351_Ser352insAlaAla p.A351_S352insAA ENST00000520004 350 ggc/ggAGCGGCc 0 +SLC9A4 UCSF GRCh37 2 103148842 103148842 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Pri Untested WXS Illumina HiSeq 78 36 142 0 ENST00000295269.4:c.2092C>T p.Arg698Trp p.R698W ENST00000295269 NM_001011552.3 698 Cgg/Tgg 0 +TEAD3 UCSF GRCh37 6 35454288 35454288 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Pri Untested WXS Illumina HiSeq 41 21 51 0 ENST00000338863.7:c.152C>T p.Pro51Leu p.P51L ENST00000338863 NM_003214.3 51 cCg/cTg 0 +TERF2IP UCSF GRCh37 16 75690462 75690462 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Pri Untested WXS Illumina HiSeq 128 82 160 0 ENST00000300086.4:c.1153T>C p.Phe385Leu p.F385L ENST00000300086 NM_018975.3 385 Ttt/Ctt 0 +TERF2IP UCSF GRCh37 16 75690302 75690302 + synonymous_variant Silent SNP A A C NOVEL P04_Pri Untested WXS Illumina HiSeq 131 83 138 0 ENST00000300086.4:c.993A>C p.Thr331= p.T331= ENST00000300086 NM_018975.3 331 acA/acC 0 +TP53 UCSF GRCh37 17 7577538 7577538 + missense_variant Missense_Mutation SNP C C T snp132_rs11540652 P04_Pri somatic WXS Sanger Illumina HiSeq 24 54 41 0 ENST00000269305.4:c.743G>A p.Arg248Gln p.R248Q ENST00000269305 NM_001126112.2 248 cGg/cAg 0 +WDFY4 UCSF GRCh37 10 50004488 50004488 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Pri Untested WXS Illumina HiSeq 116 50 143 0 ENST00000325239.5:c.4403A>G p.Asn1468Ser p.N1468S ENST00000325239 NM_020945.1 1468 aAt/aGt 0 +ZNF107 UCSF GRCh37 7 64167377 64167377 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Pri Untested WXS Illumina HiSeq 97 45 128 0 ENST00000344930.3:c.695C>G p.Thr232Ser p.T232S ENST00000344930 NM_001013746.1 232 aCt/aGt 0 +ACSF2 UCSF GRCh37 17 48541208 48541208 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 46 40 102 0 ENST00000300441.4:c.1076T>G p.Met359Arg p.M359R ENST00000300441 NM_025149.4 359 aTg/aGg 0 +ADAM17 UCSF GRCh37 2 9630335 9630335 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 77 16 75 0 ENST00000310823.3:c.2446C>T p.Arg816Cys p.R816C ENST00000310823 NM_003183.4 816 Cgt/Tgt 0 +ADAM29 UCSF GRCh37 4 175898766 175898766 + missense_variant Missense_Mutation SNP T T A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 117 27 111 0 ENST00000359240.3:c.2090T>A p.Leu697His p.L697H ENST00000359240 NM_014269.4 697 cTt/cAt 0 +APOPT1 UCSF GRCh37 14 104040439 104040465 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TTAAGGAAAAAGAAGAATTTATTCACT TTAAGGAAAAAGAAGAATTTATTCACT AAGGAAAAAGAAGAATTTTTTAACC NOVEL P04_Rec1 Untested WXS Illumina HiSeq 6 0 ENST00000409074.2:c.361-5_382delinsAAGGAAAAAGAAGAATTTTTTAACC p.X121_splice ENST00000409074 NM_032374.3 0 +ATXN2L UCSF GRCh37 16 28840741 28840741 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 70 17 82 0 ENST00000336783.4:c.761A>G p.Asn254Ser p.N254S ENST00000336783 NM_007245.3 254 aAt/aGt 0 +BOD1L UCSF GRCh37 4 13604659 13604659 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec1 Untested WXS Illumina HiSeq 151 111 170 0 ENST00000040738.5:c.3865G>A p.Val1289Ile p.V1289I ENST00000040738 NM_148894.2 1289 Gtt/Att 0 +C5orf54 UCSF GRCh37 5 159822214 159822214 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 186 21 168 0 ENST00000408953.3:c.284C>T p.Ser95Leu p.S95L ENST00000408953 NM_022090.3 95 tCg/tTg 0 +C6orf201 UCSF GRCh37 6 4087953 4087953 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 121 165 123 0 ENST00000380175.4:c.78G>C p.Lys26Asn p.K26N ENST00000380175 NM_001085401.2 26 aaG/aaC 0 +CDH7 UCSF GRCh37 18 63481815 63481815 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.013,1000g2011may_all_0.0353,snp132_rs17075245 P04_Rec1 Untested WXS Illumina HiSeq 111 82 141 0 ENST00000323011.3:c.600G>A p.Pro200= p.P200= ENST00000323011 NM_033646.1 200 ccG/ccA 0 +CYP2C9 UCSF GRCh37 10 96702051 96702051 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 90 56 121 0 ENST00000260682.6:c.434T>C p.Val145Ala p.V145A ENST00000260682 NM_000771.3 145 gTt/gCt 0 +DEFB126 UCSF GRCh37 20 126310 126311 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P04_Rec1 Untested WXS Illumina HiSeq 9 0 ENST00000382398.3:c.313_314del p.Thr105ProfsTer? p.T105Pfs*? ENST00000382398 NM_030931.3 105 ACc/c 0 +FAM206A UCSF GRCh37 9 111701942 111701942 + synonymous_variant Silent SNP T T C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 99 63 123 0 ENST00000322940.6:c.522T>C p.Ile174= p.I174= ENST00000322940 NM_017832.3 174 atT/atC 0 +FUT11 UCSF GRCh37 10 75532510 75532510 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 10 6 18 0 ENST00000372841.3:c.419A>G p.Gln140Arg p.Q140R ENST00000372841 NM_173540.2 140 cAg/cGg 0 +HEY2 UCSF GRCh37 6 126080810 126080810 + synonymous_variant Silent SNP C C T NOVEL P04_Rec1 somatic WXS Sanger Illumina HiSeq 65 42 97 0 ENST00000368364.3:c.876C>T p.Asn292= p.N292= ENST00000368364 NM_012259.2 292 aaC/aaT 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 101 61 91 0 ENST00000345146.2:c.394C>T p.Arg132Cys p.R132C ENST00000345146 NM_005896.2 132 Cgt/Tgt 0 +KIAA1731 UCSF GRCh37 11 93432660 93432660 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 223 68 184 0 ENST00000325212.6:c.4582G>C p.Glu1528Gln p.E1528Q ENST00000325212 1528 Gaa/Caa 0 +KRT83 UCSF GRCh37 12 52711478 52711478 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec1 Untested WXS Illumina HiSeq 93 13 88 0 ENST00000293670.3:c.737G>A p.Arg246Gln p.R246Q ENST00000293670 NM_002282.3 246 cGg/cAg 0 +LSG1 UCSF GRCh37 3 194369475 194369475 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 74 56 99 0 ENST00000265245.5:c.1478C>T p.Thr493Met p.T493M ENST00000265245 NM_018385.2 493 aCg/aTg 0 +MACF1 UCSF GRCh37 1 39934319 39934319 + synonymous_variant Silent SNP T T C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 93 26 108 0 ENST00000372915.3:c.21483T>C p.Arg7161= p.R7161= ENST00000372915 7161 cgT/cgC 0 +MGAT4C UCSF GRCh37 12 86373731 86373731 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 141 43 120 0 ENST00000548651.1:c.773G>C p.Gly258Ala p.G258A ENST00000548651 NM_013244.3 258 gGc/gCc 0 +MRPL55 UCSF GRCh37 1 228295410 228295410 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 31 6 33 2 ENST00000295008.4:c.187A>C p.Thr63Pro p.T63P ENST00000295008 NM_181464.2 63 Acc/Ccc 0 +MRPS6 UCSF GRCh37 21 35514779 35514779 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 112 16 73 0 ENST00000399312.2:c.257T>C p.Ile86Thr p.I86T ENST00000399312 NM_032476.3 86 aTa/aCa 0 +MUC16 UCSF GRCh37 19 9070009 9070009 + stop_gained Nonsense_Mutation SNP C C A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 137 123 167 0 ENST00000397910.4:c.17437G>T p.Glu5813Ter p.E5813* ENST00000397910 NM_024690.2 5813 Gag/Tag 0 +OR10T2 UCSF GRCh37 1 158368385 158368385 + missense_variant Missense_Mutation SNP C C A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 65 29 88 0 ENST00000334438.1:c.872G>T p.Ser291Ile p.S291I ENST00000334438 NM_001004475.1 291 aGt/aTt 0 +PDZD2 UCSF GRCh37 5 32087897 32087897 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec1 somatic WXS Sanger Illumina HiSeq 36 11 40 0 ENST00000438447.1:c.4343A>G p.Asp1448Gly p.D1448G ENST00000438447 1448 gAc/gGc 0 +PSAPL1 UCSF GRCh37 4 7435803 7435803 + synonymous_variant Silent SNP G G A NOVEL P04_Rec1 somatic WXS Sanger Illumina HiSeq 59 51 122 0 ENST00000319098.4:c.804C>T p.Ala268= p.A268= ENST00000319098 NM_001085382.1 268 gcC/gcT 0 +RAP1GAP2 UCSF GRCh37 17 2909313 2909313 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec1 Untested WXS Illumina HiSeq 80 24 65 0 ENST00000254695.8:c.1337C>T p.Ser446Leu p.S446L ENST00000254695 NM_015085.4 446 tCg/tTg 0 +RIMBP2 UCSF GRCh37 12 130926571 130926571 + synonymous_variant Silent SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 81 16 81 0 ENST00000261655.4:c.1275C>T p.Asn425= p.N425= ENST00000261655 NM_015347.4 425 aaC/aaT 0 +SLC9A4 UCSF GRCh37 2 103148842 103148842 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec1 Untested WXS Illumina HiSeq 81 64 142 0 ENST00000295269.4:c.2092C>T p.Arg698Trp p.R698W ENST00000295269 NM_001011552.3 698 Cgg/Tgg 0 +SPATA6 UCSF GRCh37 1 48764545 48764545 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 156 43 126 0 ENST00000371847.3:c.1307G>C p.Gly436Ala p.G436A ENST00000371847 NM_019073.2 436 gGc/gCc 0 +TDG UCSF GRCh37 12 104373729 104373730 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 9 0 ENST00000392872.3:c.292dup p.Ile98AsnfsTer6 p.I98Nfs*6 ENST00000392872 NM_003211.4 96 gaa/gaAa 0 +TEAD3 UCSF GRCh37 6 35454288 35454288 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 28 40 51 0 ENST00000338863.7:c.152C>T p.Pro51Leu p.P51L ENST00000338863 NM_003214.3 51 cCg/cTg 0 +TP53 UCSF GRCh37 17 7577538 7577538 + missense_variant Missense_Mutation SNP C C T snp132_rs11540652 P04_Rec1 somatic WXS Sanger Illumina HiSeq 5 58 41 0 ENST00000269305.4:c.743G>A p.Arg248Gln p.R248Q ENST00000269305 NM_001126112.2 248 cGg/cAg 0 +ZNF107 UCSF GRCh37 7 64167377 64167377 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 109 50 128 0 ENST00000344930.3:c.695C>G p.Thr232Ser p.T232S ENST00000344930 NM_001013746.1 232 aCt/aGt 0 +ACSF2 UCSF GRCh37 17 48541208 48541208 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Rec2 Untested WXS Illumina HiSeq 38 27 102 0 ENST00000300441.4:c.1076T>G p.Met359Arg p.M359R ENST00000300441 NM_025149.4 359 aTg/aGg 0 +APOBEC4 UCSF GRCh37 1 183617696 183617696 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec2 somatic WXS Sanger Illumina HiSeq 91 54 145 0 ENST00000308641.4:c.221C>G p.Ser74Cys p.S74C ENST00000308641 NM_203454.2 74 tCt/tGt 0 +BOD1L UCSF GRCh37 4 13604659 13604659 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 71 62 170 0 ENST00000040738.5:c.3865G>A p.Val1289Ile p.V1289I ENST00000040738 NM_148894.2 1289 Gtt/Att 0 +CDH7 UCSF GRCh37 18 63481815 63481815 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.013,1000g2011may_all_0.0353,snp132_rs17075245 P04_Rec2 Untested WXS Illumina HiSeq 66 49 141 0 ENST00000323011.3:c.600G>A p.Pro200= p.P200= ENST00000323011 NM_033646.1 200 ccG/ccA 0 +CFH UCSF GRCh37 1 196694259 196694259 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec2 Untested WXS Illumina HiSeq 70 44 95 0 ENST00000367429.4:c.1705T>C p.Cys569Arg p.C569R ENST00000367429 NM_000186.3 569 Tgc/Cgc 0 +CLASP1 UCSF GRCh37 2 122182732 122182732 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec2 Untested WXS Illumina HiSeq 59 62 135 0 ENST00000263710.4:c.2195C>G p.Pro732Arg p.P732R ENST00000263710 NM_015282.2 732 cCa/cGa 0 +COL13A1 UCSF GRCh37 10 71684757 71684757 + synonymous_variant Silent SNP C C T NOVEL P04_Rec2 somatic WXS Sanger Illumina HiSeq 18 8 25 0 ENST00000398978.3:c.1290C>T p.Gly430= p.G430= ENST00000398978 NM_001130103.1 430 ggC/ggT 0 +DPYSL4 UCSF GRCh37 10 134006219 134006219 + synonymous_variant Silent SNP C C G NOVEL P04_Rec2 Untested WXS Illumina HiSeq 54 23 95 0 ENST00000338492.4:c.186C>G p.Gly62= p.G62= ENST00000338492 NM_006426.2 62 ggC/ggG 0 +GABRE UCSF GRCh37 X 151123975 151123975 + synonymous_variant Silent SNP G G A NOVEL P04_Rec2 somatic WXS Sanger Illumina HiSeq 8 58 71 0 ENST00000370328.3:c.1002C>T p.Val334= p.V334= ENST00000370328 NM_004961.3 334 gtC/gtT 0 +GPR112 UCSF GRCh37 X 135453557 135453557 + missense_variant Missense_Mutation SNP G G T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 5 42 51 0 ENST00000370652.1:c.7467G>T p.Glu2489Asp p.E2489D ENST00000370652 2489 gaG/gaT 0 +GULP1 UCSF GRCh37 2 189449083 189449083 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec2 Untested WXS Illumina HiSeq 84 52 131 0 ENST00000359135.3:c.701G>A p.Arg234His p.R234H ENST00000359135 234 cGc/cAc 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec2 Untested WXS Illumina HiSeq 61 38 91 0 ENST00000345146.2:c.394C>T p.Arg132Cys p.R132C ENST00000345146 NM_005896.2 132 Cgt/Tgt 0 +LAMA3 UCSF GRCh37 18 21484018 21484018 + missense_variant Missense_Mutation SNP G G T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 60 44 126 0 ENST00000313654.9:c.6440G>T p.Arg2147Leu p.R2147L ENST00000313654 NM_198129.1 2147 cGg/cTg 0 +PHRF1 UCSF GRCh37 11 587424 587424 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec2 Untested WXS Illumina HiSeq 38 49 99 0 ENST00000264555.5:c.380C>G p.Ala127Gly p.A127G ENST00000264555 NM_020901.2 127 gCc/gGc 0 +PSAP UCSF GRCh37 10 73579333 73579334 + frameshift_variant Frame_Shift_Ins INS - - CTTG NOVEL P04_Rec2 Untested WXS Illumina HiSeq 18 0 ENST00000394936.3:c.1238_1239insCAAG p.Lys413AsnfsTer26 p.K413Nfs*26 ENST00000394936 413 aag/aaCAAGg 0 +SLC9A4 UCSF GRCh37 2 103148842 103148842 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 52 33 142 0 ENST00000295269.4:c.2092C>T p.Arg698Trp p.R698W ENST00000295269 NM_001011552.3 698 Cgg/Tgg 0 +SLCO1B7 UCSF GRCh37 12 21200142 21200142 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P04_Rec2 Untested WXS Illumina HiSeq 41 0 ENST00000421593.2:c.989del p.Leu330CysfsTer28 p.L330Cfs*28 ENST00000421593 NM_001009562.4 329 Ttt/tt 0 +SNRPB UCSF GRCh37 20 2443747 2443747 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 39 38 103 0 ENST00000438552.2:c.547G>A p.Ala183Thr p.A183T ENST00000438552 NM_198216.1 183 Gca/Aca 0 +SPIRE1 UCSF GRCh37 18 12449679 12449679 + synonymous_variant Silent SNP G G C NOVEL P04_Rec2 somatic WXS Sanger Illumina HiSeq 29 29 96 0 ENST00000409402.4:c.2229C>G p.Pro743= p.P743= ENST00000409402 NM_001128626.1 743 ccC/ccG 0 +TEAD3 UCSF GRCh37 6 35454288 35454288 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec2 Untested WXS Illumina HiSeq 23 14 51 0 ENST00000338863.7:c.152C>T p.Pro51Leu p.P51L ENST00000338863 NM_003214.3 51 cCg/cTg 0 +TP53 UCSF GRCh37 17 7577538 7577538 + missense_variant Missense_Mutation SNP C C T snp132_rs11540652 P04_Rec2 somatic WXS Sanger Illumina HiSeq 2 28 41 0 ENST00000269305.4:c.743G>A p.Arg248Gln p.R248Q ENST00000269305 NM_001126112.2 248 cGg/cAg 0 +UBQLNL UCSF GRCh37 11 5536309 5536309 + missense_variant Missense_Mutation SNP G G C 1000g2010nov_all_0.027,1000g2011may_all_0.04739,snp132_rs12223282 P04_Rec2 Untested WXS Illumina HiSeq 48 47 133 0 ENST00000380184.1:c.1363C>G p.Gln455Glu p.Q455E ENST00000380184 NM_145053.4 455 Cag/Gag 0 +WDR72 UCSF GRCh37 15 54004993 54004993 + synonymous_variant Silent SNP C C T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 55 43 93 0 ENST00000360509.5:c.687G>A p.Leu229= p.L229= ENST00000360509 229 ttG/ttA 0 +ZNF107 UCSF GRCh37 7 64167377 64167377 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec2 Untested WXS Illumina HiSeq 70 40 128 0 ENST00000344930.3:c.695C>G p.Thr232Ser p.T232S ENST00000344930 NM_001013746.1 232 aCt/aGt 0 +ACSF2 UCSF GRCh37 17 48541208 48541208 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 59 41 102 0 ENST00000300441.4:c.1076T>G p.Met359Arg p.M359R ENST00000300441 NM_025149.4 359 aTg/aGg 0 +AKAP6 UCSF GRCh37 14 33242972 33242973 + protein_altering_variant In_Frame_Ins INS - - GCA NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 0 ENST00000280979.4:c.3461_3462insGCA p.Cys1154delinsTrpHis p.C1154delinsWH ENST00000280979 NM_004274.4 1154 tgc/tgGCAc 0 +AKR1D1 UCSF GRCh37 7 137782608 137782611 + splice_acceptor_variant,intron_variant Splice_Site DEL TCAG TCAG CAC NOVEL P04_Rec3 Untested WXS Illumina HiSeq 7 0 ENST00000242375.3:c.379-4_379-1delinsCAC p.X127_splice ENST00000242375 NM_005989.3 0 +APOBEC4 UCSF GRCh37 1 183617696 183617696 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 89 85 145 0 ENST00000308641.4:c.221C>G p.Ser74Cys p.S74C ENST00000308641 NM_203454.2 74 tCt/tGt 0 +ARHGEF17 UCSF GRCh37 11 73076827 73076827 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 52 11 51 0 ENST00000263674.3:c.5830C>T p.Leu1944Phe p.L1944F ENST00000263674 NM_014786.3 1944 Ctc/Ttc 0 +ATXN3 UCSF GRCh37 14 92555132 92555132 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 41 0 ENST00000532032.1:c.417del p.Pro140GlnfsTer3 p.P140Qfs*3 ENST00000532032 139 ggT/gg 0 +BOD1L UCSF GRCh37 4 13604659 13604659 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 123 106 170 0 ENST00000040738.5:c.3865G>A p.Val1289Ile p.V1289I ENST00000040738 NM_148894.2 1289 Gtt/Att 0 +C1orf124 UCSF GRCh37 1 231488849 231488851 + frameshift_variant Frame_Shift_Del DEL CCC CCC A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 20 0 ENST00000295050.7:c.1212_1214delinsA p.Phe404LeufsTer3 p.F404Lfs*3 ENST00000295050 NM_032018.5 404 ttCCCa/ttAa 0 +C5orf22 UCSF GRCh37 5 31541063 31541064 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 8 0 ENST00000325366.9:c.816_817del p.Tyr272Ter p.Y272* ENST00000325366 NM_018356.2 272 tAC/t 0 +C9orf84 UCSF GRCh37 9 114486071 114486071 + splice_donor_variant Splice_Site SNP C C G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 81 15 50 0 ENST00000318737.4:c.1762+1G>C p.X588_splice ENST00000318737 NM_173521.3 0 +CASP10 UCSF GRCh37 2 202050641 202050641 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 18 0 ENST00000272879.5:c.144del p.Asn49ThrfsTer23 p.N49Tfs*23 ENST00000272879 NM_032974.4 47 gtC/gt 0 +CCR4 UCSF GRCh37 3 32994946 32994946 + missense_variant Missense_Mutation SNP T T A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 68 15 102 0 ENST00000330953.5:c.32T>A p.Leu11His p.L11H ENST00000330953 NM_005508.4 11 cTc/cAc 0 +CDH7 UCSF GRCh37 18 63481815 63481815 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.013,1000g2011may_all_0.0353,snp132_rs17075245 P04_Rec3 Untested WXS Illumina HiSeq 93 67 141 0 ENST00000323011.3:c.600G>A p.Pro200= p.P200= ENST00000323011 NM_033646.1 200 ccG/ccA 0 +CFH UCSF GRCh37 1 196694259 196694259 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 78 68 95 0 ENST00000367429.4:c.1705T>C p.Cys569Arg p.C569R ENST00000367429 NM_000186.3 569 Tgc/Cgc 0 +CHRM1 UCSF GRCh37 11 62678364 62678364 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 74 12 96 0 ENST00000306960.3:c.209C>G p.Ala70Gly p.A70G ENST00000306960 NM_000738.2 70 gCt/gGt 0 +CLASP1 UCSF GRCh37 2 122182732 122182732 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 121 106 135 0 ENST00000263710.4:c.2195C>G p.Pro732Arg p.P732R ENST00000263710 NM_015282.2 732 cCa/cGa 0 +CNKSR3 UCSF GRCh37 6 154763244 154763244 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 70 10 76 0 ENST00000607772.1:c.397G>A p.Ala133Thr p.A133T ENST00000607772 NM_173515.2 133 Gcc/Acc 0 +COL13A1 UCSF GRCh37 10 71684757 71684757 + synonymous_variant Silent SNP C C T NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 25 13 25 0 ENST00000398978.3:c.1290C>T p.Gly430= p.G430= ENST00000398978 NM_001130103.1 430 ggC/ggT 0 +CRTC2 UCSF GRCh37 1 153921068 153921068 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 95 18 92 0 ENST00000368633.1:c.1727C>T p.Pro576Leu p.P576L ENST00000368633 NM_181715.2 576 cCt/cTt 0 +CUL9 UCSF GRCh37 6 43190286 43190296 + frameshift_variant Frame_Shift_Del DEL GCGGAACCGGG GCGGAACCGGG - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 0 ENST00000252050.4:c.6939_6949del p.Leu2313PhefsTer6 p.L2313Ffs*6 ENST00000252050 NM_015089.2 2313 ttGCGGAACCGGGtg/tttg 0 +DDX60 UCSF GRCh37 4 169215051 169215051 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 118 27 114 0 ENST00000393743.3:c.769T>C p.Ser257Pro p.S257P ENST00000393743 NM_017631.5 257 Tct/Cct 0 +DGKI UCSF GRCh37 7 137172402 137172402 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 271 33 156 0 ENST00000288490.5:c.2336A>G p.Asp779Gly p.D779G ENST00000288490 NM_004717.2 779 gAc/gGc 0 +DPYSL4 UCSF GRCh37 10 134006219 134006219 + synonymous_variant Silent SNP C C G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 72 48 95 0 ENST00000338492.4:c.186C>G p.Gly62= p.G62= ENST00000338492 NM_006426.2 62 ggC/ggG 0 +DUOX1 UCSF GRCh37 15 45431646 45431649 + frameshift_variant Frame_Shift_Del DEL AGTT AGTT - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 15 0 ENST00000321429.4:c.1238_1241del p.Lys413IlefsTer66 p.K413Ifs*66 ENST00000321429 NM_017434.3 413 aAGTTt/at 0 +DYNC2H1 UCSF GRCh37 11 102984845 102984845 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 174 25 141 0 ENST00000375735.2:c.380G>A p.Ser127Asn p.S127N ENST00000375735 NM_001080463.1 127 aGc/aAc 0 +DYNC2LI1 UCSF GRCh37 2 44021791 44021791 + intron_variant Intron DEL C C - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 34 0 ENST00000260605.8:c.507+9del *169* ENST00000260605 NM_001193464.1 0 +ERC1 UCSF GRCh37 12 1192504 1192504 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 15 0 ENST00000360905.4:c.846del p.Leu283PhefsTer20 p.L283Ffs*20 ENST00000360905 282 Ttt/tt 0 +FAM75D1 UCSF GRCh37 9 84606868 84606868 + missense_variant Missense_Mutation SNP C C A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 181 52 170 0 ENST00000344803.2:c.1483C>A p.His495Asn p.H495N ENST00000344803 NM_001001670.2 495 Cat/Aat 0 +FIGNL1 UCSF GRCh37 7 50514933 50514933 + missense_variant Missense_Mutation SNP T T A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 87 21 79 0 ENST00000356889.4:c.53A>T p.Tyr18Phe p.Y18F ENST00000356889 NM_001287495.1 18 tAc/tTc 0 +FIGNL1 UCSF GRCh37 7 50514932 50514932 + synonymous_variant Silent SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 89 21 80 0 ENST00000356889.4:c.54C>T p.Tyr18= p.Y18= ENST00000356889 NM_001287495.1 18 taC/taT 0 +GABRE UCSF GRCh37 X 151123975 151123975 + synonymous_variant Silent SNP G G A NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 9 92 71 0 ENST00000370328.3:c.1002C>T p.Val334= p.V334= ENST00000370328 NM_004961.3 334 gtC/gtT 0 +GLMN UCSF GRCh37 1 92713511 92713511 + synonymous_variant Silent SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 124 26 70 0 ENST00000370360.3:c.1509T>C p.Asn503= p.N503= ENST00000370360 NM_053274.2 503 aaT/aaC 0 +GPR112 UCSF GRCh37 X 135453557 135453557 + missense_variant Missense_Mutation SNP G G T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 52 51 0 ENST00000370652.1:c.7467G>T p.Glu2489Asp p.E2489D ENST00000370652 2489 gaG/gaT 0 +GRWD1 UCSF GRCh37 19 48955968 48955968 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 34 13 61 0 ENST00000253237.5:c.1027G>A p.Gly343Ser p.G343S ENST00000253237 NM_031485.3 343 Ggt/Agt 0 +GULP1 UCSF GRCh37 2 189449083 189449083 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 86 62 131 0 ENST00000359135.3:c.701G>A p.Arg234His p.R234H ENST00000359135 234 cGc/cAc 0 +HMBOX1 UCSF GRCh37 8 28827573 28827573 + missense_variant Missense_Mutation SNP A A C NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 138 31 114 0 ENST00000287701.10:c.37A>C p.Met13Leu p.M13L ENST00000287701 NM_001135726.1 13 Atg/Ctg 0 +HPS4 UCSF GRCh37 22 26862199 26862199 + missense_variant Missense_Mutation SNP C C A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 84 12 87 0 ENST00000336873.5:c.699G>T p.Gln233His p.Q233H ENST00000336873 233 caG/caT 0 +HSP90AB1 UCSF GRCh37 6 44217180 44217180 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 184 21 176 0 ENST00000353801.3:c.214A>G p.Lys72Glu p.K72E ENST00000353801 NM_001271969.1 72 Aaa/Gaa 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 94 62 91 0 ENST00000345146.2:c.394C>T p.Arg132Cys p.R132C ENST00000345146 NM_005896.2 132 Cgt/Tgt 0 +IK UCSF GRCh37 5 140041897 140041897 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 30 0 ENST00000417647.2:c.1660del p.Arg554AspfsTer7 p.R554Dfs*7 ENST00000417647 NM_006083.3 553 Aaa/aa 0 +ITIH5L UCSF GRCh37 X 54785050 54785050 + missense_variant Missense_Mutation SNP A A T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 22 14 31 0 ENST00000218436.6:c.1457T>A p.Val486Asp p.V486D ENST00000218436 NM_198510.2 486 gTt/gAt 0 +KCTD16 UCSF GRCh37 5 143587110 143587110 + splice_donor_variant Splice_Site SNP G G T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 87 12 88 0 ENST00000507359.3:c.832+1G>T p.X278_splice ENST00000507359 NM_020768.3 0 +LAMA3 UCSF GRCh37 18 21484018 21484018 + missense_variant Missense_Mutation SNP G G T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 76 62 126 0 ENST00000313654.9:c.6440G>T p.Arg2147Leu p.R2147L ENST00000313654 NM_198129.1 2147 cGg/cTg 0 +MBD4 UCSF GRCh37 3 129155548 129155548 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 0 ENST00000249910.1:c.939delA p.Glu314LysfsTer4 p.E314Kfs*4 ENST00000249910 313 aaA/aa 0 +MTTP UCSF GRCh37 4 100521799 100521799 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 125 31 125 0 ENST00000265517.5:c.1145A>G p.Lys382Arg p.K382R ENST00000265517 382 aAa/aGa 0 +MUC4 UCSF GRCh37 3 195506723 195506770 + inframe_deletion In_Frame_Del DEL TGTCGGTGACAGGAAGAGGGGTGGCGTGACGTGTGGATGCTGAGGAAG TGTCGGTGACAGGAAGAGGGGTGGCGTGACGTGTGGATGCTGAGGAAG - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 8 0 ENST00000463781.3:c.11691_11738del p.Arg3900_Thr3915del p.R3900_T3915del ENST00000463781 NM_018406.6 3894 aCTTCCTCAGCATCCACACGTCACGCCACCCCTCTTCCTGTCACCGACAct/act 0 +MUC5B UCSF GRCh37 11 1253980 1253980 + missense_variant Missense_Mutation SNP A A G 1000g2010nov_all_0.103,snp132_rs115853043 P04_Rec3 Untested WXS Illumina HiSeq 10 4 15 1 ENST00000529681.1:c.2045A>G p.Asp682Gly p.D682G ENST00000529681 NM_002458.2 682 gAc/gGc 0 +PHRF1 UCSF GRCh37 11 587424 587424 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 66 37 99 0 ENST00000264555.5:c.380C>G p.Ala127Gly p.A127G ENST00000264555 NM_020901.2 127 gCc/gGc 0 +PSAP UCSF GRCh37 10 73579333 73579334 + frameshift_variant Frame_Shift_Ins INS - - CTTG NOVEL P04_Rec3 Untested WXS Illumina HiSeq 32 0 ENST00000394936.3:c.1238_1239insCAAG p.Lys413AsnfsTer26 p.K413Nfs*26 ENST00000394936 413 aag/aaCAAGg 0 +RFC3 UCSF GRCh37 13 34398063 34398063 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 0 ENST00000380071.3:c.244delA p.Ile82LeufsTer25 p.I82Lfs*25 ENST00000380071 NM_002915.3 79 Aaa/aa 0 +SH3TC1 UCSF GRCh37 4 8242506 8242509 + frameshift_variant Frame_Shift_Del DEL ATCT ATCT - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 11 0 ENST00000245105.3:c.3836_3839del p.Ile1279ThrfsTer96 p.I1279Tfs*96 ENST00000245105 NM_018986.3 1279 ATCTac/ac 0 +SLC9A4 UCSF GRCh37 2 103148842 103148842 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 91 53 142 0 ENST00000295269.4:c.2092C>T p.Arg698Trp p.R698W ENST00000295269 NM_001011552.3 698 Cgg/Tgg 0 +SLCO1B7 UCSF GRCh37 12 21200142 21200142 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 70 0 ENST00000421593.2:c.989del p.Leu330CysfsTer28 p.L330Cfs*28 ENST00000421593 NM_001009562.4 329 Ttt/tt 0 +SNRPB UCSF GRCh37 20 2443747 2443747 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 65 48 103 0 ENST00000438552.2:c.547G>A p.Ala183Thr p.A183T ENST00000438552 NM_198216.1 183 Gca/Aca 0 +SORCS1 UCSF GRCh37 10 108431048 108431048 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 16 0 ENST00000263054.6:c.2136del p.Tyr712Ter p.Y712* ENST00000263054 NM_001206570.1 712 taT/ta 0 +SPIRE1 UCSF GRCh37 18 12449679 12449679 + synonymous_variant Silent SNP G G C NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 49 49 96 0 ENST00000409402.4:c.2229C>G p.Pro743= p.P743= ENST00000409402 NM_001128626.1 743 ccC/ccG 0 +TEAD3 UCSF GRCh37 6 35454288 35454288 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 29 35 51 0 ENST00000338863.7:c.152C>T p.Pro51Leu p.P51L ENST00000338863 NM_003214.3 51 cCg/cTg 0 +TP53 UCSF GRCh37 17 7577538 7577538 + missense_variant Missense_Mutation SNP C C T snp132_rs11540652 P04_Rec3 somatic WXS Sanger Illumina HiSeq 7 43 41 0 ENST00000269305.4:c.743G>A p.Arg248Gln p.R248Q ENST00000269305 NM_001126112.2 248 cGg/cAg 0 +UBQLNL UCSF GRCh37 11 5536309 5536309 + missense_variant Missense_Mutation SNP G G C 1000g2010nov_all_0.027,1000g2011may_all_0.04739,snp132_rs12223282 P04_Rec3 Untested WXS Illumina HiSeq 83 84 133 0 ENST00000380184.1:c.1363C>G p.Gln455Glu p.Q455E ENST00000380184 NM_145053.4 455 Cag/Gag 0 +USP24 UCSF GRCh37 1 55591187 55591187 + synonymous_variant Silent SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 210 39 182 0 ENST00000294383.6:c.3766T>C p.Leu1256= p.L1256= ENST00000294383 NM_015306.2 1256 Tta/Cta 0 +WDR72 UCSF GRCh37 15 54004993 54004993 + synonymous_variant Silent SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 77 57 93 0 ENST00000360509.5:c.687G>A p.Leu229= p.L229= ENST00000360509 229 ttG/ttA 0 +WWC3 UCSF GRCh37 X 10046914 10046914 + frameshift_variant,splice_region_variant Frame_Shift_Del DEL G G - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 27 0 ENST00000380861.4:c.297+1del R99fs ENST00000380861 NM_015691.3 99 aGg/ag 0 +ZNF107 UCSF GRCh37 7 64167377 64167377 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 90 58 128 0 ENST00000344930.3:c.695C>G p.Thr232Ser p.T232S ENST00000344930 NM_001013746.1 232 aCt/aGt 0 +ZNF135 UCSF GRCh37 19 58579378 58579378 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 148 27 145 1 ENST00000313434.5:c.1526T>C p.Leu509Pro p.L509P ENST00000313434 NM_003436.3 509 cTc/cCc 0 +ZZEF1 UCSF GRCh37 17 3917753 3917753 + stop_gained Nonsense_Mutation SNP G G T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 128 33 115 0 ENST00000381638.2:c.8202C>A p.Cys2734Ter p.C2734* ENST00000381638 NM_015113.3 2734 tgC/tgA 0 +AHCYL1 UCSF GRCh37 1 110561727 110561727 + missense_variant Missense_Mutation SNP A A C snp132_rs75754234 P05_Pri Untested WXS Illumina HiSeq 36 7 56 1 ENST00000369799.5:c.1372A>C p.Thr458Pro p.T458P ENST00000369799 NM_001242674.1 458 Aca/Cca 0 +ARID2 UCSF GRCh37 12 46244079 46244079 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Pri Untested WXS Illumina HiSeq 63 27 100 0 ENST00000334344.6:c.2173C>T p.Gln725Ter p.Q725* ENST00000334344 NM_152641.2 725 Cag/Tag 0 +ATAD5 UCSF GRCh37 17 29219740 29219740 + missense_variant Missense_Mutation SNP T T G snp132_rs74661926 P05_Pri Untested WXS Illumina HiSeq 61 15 101 0 ENST00000321990.4:c.4374T>G p.Cys1458Trp p.C1458W ENST00000321990 NM_024857.3 1458 tgT/tgG 0 +ATRX UCSF GRCh37 X 76890167 76890167 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Pri somatic WXS Sanger Illumina HiSeq 44 23 140 0 ENST00000373344.5:c.4727G>A p.Cys1576Tyr p.C1576Y ENST00000373344 NM_000489.3 1576 tGt/tAt 0 +ATRX UCSF GRCh37 X 76875979 76875979 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Pri Untested WXS Illumina HiSeq 52 9 54 0 ENST00000373344.5:c.5156A>G p.Asp1719Gly p.D1719G ENST00000373344 NM_000489.3 1719 gAt/gGt 0 +C6orf103 UCSF GRCh37 6 147012388 147012388 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 74 32 122 0 ENST00000397944.3:c.1448G>A p.Arg483His p.R483H ENST00000397944 NM_024694.3 483 cGt/cAt 0 +C7orf63 UCSF GRCh37 7 89906426 89906426 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Pri Untested WXS Illumina HiSeq 60 29 24 0 ENST00000389297.4:c.1024T>C p.Phe342Leu p.F342L ENST00000389297 NM_001039706.2 342 Ttt/Ctt 0 +CASP12 UCSF GRCh37 11 104761174 104761174 + synonymous_variant Silent SNP A A G NOVEL P05_Pri Untested WXS Illumina HiSeq 32 4 36 1 ENST00000422698.2:c.744T>C p.Gly248= p.G248= ENST00000422698 NM_001191016.1 248 ggT/ggC 0 +CCNC UCSF GRCh37 6 99993044 99993044 + synonymous_variant Silent SNP T T C NOVEL P05_Pri Untested WXS Illumina HiSeq 67 19 49 0 ENST00000520429.1:c.741A>G p.Arg247= p.R247= ENST00000520429 NM_005190.3 247 agA/agG 0 +CEACAM6 UCSF GRCh37 19 42260811 42260811 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P05_Pri Untested WXS Illumina HiSeq 38 0 ENST00000199764.6:c.369del p.Val124SerfsTer2 p.V124Sfs*2 ENST00000199764 NM_002483.4 123 cAa/ca 0 +CELA3B UCSF GRCh37 1 22310235 22310235 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.009,snp132_rs113497474 P05_Pri Untested WXS Illumina HiSeq 17 4 62 1 ENST00000337107.6:c.411C>T p.Asp137= p.D137= ENST00000337107 NM_007352.2 137 gaC/gaT 0 +CIT UCSF GRCh37 12 120148087 120148087 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Pri Untested WXS Illumina HiSeq 60 18 99 0 ENST00000261833.7:c.4914C>G p.Ile1638Met p.I1638M ENST00000261833 NM_007174.2 1638 atC/atG 0 +CLK2 UCSF GRCh37 1 155238508 155238508 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Pri Untested WXS Illumina HiSeq 24 8 27 1 ENST00000368361.4:c.478C>A p.Gln160Lys p.Q160K ENST00000368361 160 Caa/Aaa 0 +CNNM2 UCSF GRCh37 10 104679671 104679671 + stop_gained Nonsense_Mutation SNP C C A NOVEL P05_Pri Untested WXS Illumina HiSeq 43 9 52 0 ENST00000369878.4:c.1434C>A p.Tyr478Ter p.Y478* ENST00000369878 NM_017649.4 478 taC/taA 0 +CSMD3 UCSF GRCh37 8 113326817 113326817 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Pri Untested WXS Illumina HiSeq 44 11 53 1 ENST00000297405.5:c.7390G>A p.Asp2464Asn p.D2464N ENST00000297405 NM_198123.1 2464 Gat/Aat 0 +FGF9 UCSF GRCh37 13 22246317 22246317 + missense_variant Missense_Mutation SNP A A C snp132_rs117849081 P05_Pri Untested WXS Illumina HiSeq 9 6 56 1 ENST00000382353.5:c.266A>C p.His89Pro p.H89P ENST00000382353 NM_002010.2 89 cAc/cCc 0 +GPC3 UCSF GRCh37 X 132888089 132888089 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Pri Untested WXS Illumina HiSeq 52 18 157 0 ENST00000370818.3:c.452A>T p.Asp151Val p.D151V ENST00000370818 NM_001164618.1 151 gAt/gTt 0 +HHLA1 UCSF GRCh37 8 133092007 133092007 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Pri Untested WXS Illumina HiSeq 12 11 15 1 ENST00000414222.1:c.883A>C p.Thr295Pro p.T295P ENST00000414222 NM_001145095.1 295 Aca/Cca 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Pri Untested WXS Illumina HiSeq 40 24 75 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL1R1 UCSF GRCh37 2 102785059 102785059 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 44 18 57 0 ENST00000410023.1:c.657G>A p.Glu219= p.E219= ENST00000410023 219 gaG/gaA 0 +LRRC33 UCSF GRCh37 3 196388593 196388593 + stop_lost Nonstop_Mutation SNP A A G NOVEL P05_Pri Untested WXS Illumina HiSeq 16 3 35 0 ENST00000328557.4:c.2079A>G p.Ter693TrpextTer25 p.*693Wext*25 ENST00000328557 NM_198565.1 693 tgA/tgG 0 +LYVE1 UCSF GRCh37 11 10582206 10582206 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 50 16 85 0 ENST00000256178.3:c.539C>T p.Ala180Val p.A180V ENST00000256178 NM_006691.3 180 gCc/gTc 0 +MAGEC1 UCSF GRCh37 X 140994085 140994085 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.09062,1000g2011may_all_0.1531,snp132_rs176046 P05_Pri Untested WXS Illumina HiSeq 44 8 43 0 ENST00000285879.4:c.895C>G p.Pro299Ala p.P299A ENST00000285879 NM_005462.4 299 Ccc/Gcc 0 +MAP2 UCSF GRCh37 2 210569173 210569173 + intron_variant Intron SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 50 10 45 1 ENST00000360351.4:c.4585-1131G>A *1529* ENST00000360351 NM_002374.3 0 +NR1I3 UCSF GRCh37 1 161203098 161203098 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Pri Untested WXS Illumina HiSeq 27 7 72 0 ENST00000367982.4:c.269G>A p.Arg90Gln p.R90Q ENST00000367982 90 cGg/cAg 0 +PCDH17 UCSF GRCh37 13 58298890 58298890 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Pri Untested WXS Illumina HiSeq 58 11 83 0 ENST00000377918.3:c.2942A>C p.Asn981Thr p.N981T ENST00000377918 NM_001040429.2 981 aAt/aCt 0 +PRDM5 UCSF GRCh37 4 121698436 121698436 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P05_Pri Untested WXS Illumina HiSeq 56 10 68 0 ENST00000264808.3:c.1444A>G p.Thr482Ala p.T482A ENST00000264808 NM_018699.2 482 Aca/Gca 0 +PRR14 UCSF GRCh37 16 30664057 30664057 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Pri Untested WXS Illumina HiSeq 11 5 44 0 ENST00000300835.4:c.208T>A p.Ser70Thr p.S70T ENST00000300835 NM_024031.2 70 Tca/Aca 0 +PZP UCSF GRCh37 12 9345272 9345272 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.00093 P05_Pri Untested WXS Illumina HiSeq 28 7 88 0 ENST00000261336.2:c.1318G>A p.Ala440Thr p.A440T ENST00000261336 NM_002864.2 440 Gct/Act 0 +SCN11A UCSF GRCh37 3 38888584 38888584 + synonymous_variant Silent SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 83 21 128 0 ENST00000302328.3:c.4977C>T p.Val1659= p.V1659= ENST00000302328 NM_014139.2 1659 gtC/gtT 0 +TSHZ3 UCSF GRCh37 19 31767507 31767507 + synonymous_variant Silent SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 43 18 58 0 ENST00000240587.4:c.3192C>T p.His1064= p.H1064= ENST00000240587 NM_020856.2 1064 caC/caT 0 +TSPEAR UCSF GRCh37 21 45945556 45945556 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 31 18 73 0 ENST00000323084.4:c.1316C>T p.Ala439Val p.A439V ENST00000323084 NM_001272037.1 439 gCg/gTg 0 +UNC13C UCSF GRCh37 15 54307971 54307971 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Pri Untested WXS Illumina HiSeq 19 12 39 0 ENST00000260323.11:c.2871A>C p.Glu957Asp p.E957D ENST00000260323 NM_001080534.1 957 gaA/gaC 0 +VIT UCSF GRCh37 2 37041424 37041424 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 23 4 71 0 ENST00000389975.3:c.1957G>A p.Glu653Lys p.E653K ENST00000389975 NM_001177970.1 653 Gag/Aag 0 +ZFAND2B UCSF GRCh37 2 220072104 220072104 + synonymous_variant Silent SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 12 5 47 0 ENST00000289528.5:c.111G>A p.Val37= p.V37= ENST00000289528 NM_001270999.1 37 gtG/gtA 0 +ZNF485 UCSF GRCh37 10 44104090 44104090 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Pri Untested WXS Illumina HiSeq 28 12 58 2 ENST00000361807.3:c.53T>G p.Val18Gly p.V18G ENST00000361807 NM_145312.3 18 gTg/gGg 0 +A2M UCSF GRCh37 12 9264996 9264996 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 73 139 0 ENST00000318602.7:c.407C>T p.Ser136Leu p.S136L ENST00000318602 NM_000014.4 136 tCa/tTa 0 +A4GNT UCSF GRCh37 3 137849742 137849742 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 40 87 0 ENST00000236709.3:c.357G>A p.Leu119= p.L119= ENST00000236709 NM_016161.2 119 ttG/ttA 0 +AAMP UCSF GRCh37 2 219131667 219131667 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 63 68 0 ENST00000248450.4:c.437C>T p.Ser146Phe p.S146F ENST00000248450 146 tCc/tTc 0 +AANAT UCSF GRCh37 17 74464874 74464874 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 6 11 0 ENST00000392492.3:c.46C>T p.Leu16= p.L16= ENST00000392492 NM_001088.2 16 Ctg/Ttg 0 +AARS UCSF GRCh37 16 70298924 70298924 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 25 34 0 ENST00000261772.8:c.1429G>A p.Gly477Ser p.G477S ENST00000261772 NM_001605.2 477 Ggt/Agt 0 +AASDH UCSF GRCh37 4 57204659 57204659 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 37 58 0 ENST00000205214.6:c.3206C>T p.Ser1069Phe p.S1069F ENST00000205214 NM_181806.2 1069 tCt/tTt 0 +AASS UCSF GRCh37 7 121773620 121773620 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 32 93 0 ENST00000393376.1:c.161G>A p.Gly54Glu p.G54E ENST00000393376 54 gGa/gAa 0 +ABCA1 UCSF GRCh37 9 107547804 107547804 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 50 72 0 ENST00000374736.3:c.6518G>A p.Arg2173Gln p.R2173Q ENST00000374736 NM_005502.3 2173 cGg/cAg 0 +ABCA12 UCSF GRCh37 2 215891637 215891637 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 163 108 103 0 ENST00000272895.7:c.1087G>A p.Asp363Asn p.D363N ENST00000272895 NM_173076.2 363 Gat/Aat 0 +ABCA13 UCSF GRCh37 7 48414007 48414007 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 123 48 102 0 ENST00000435803.1:c.11197G>A p.Glu3733Lys p.E3733K ENST00000435803 NM_152701.3 3733 Gag/Aag 0 +ABCA4 UCSF GRCh37 1 94546147 94546147 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 49 95 0 ENST00000370225.3:c.986G>A p.Gly329Glu p.G329E ENST00000370225 NM_000350.2 329 gGa/gAa 0 +ABCA9 UCSF GRCh37 17 66982360 66982360 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 29 61 0 ENST00000340001.4:c.4153G>A p.Val1385Met p.V1385M ENST00000340001 NM_080283.3 1385 Gtg/Atg 0 +ABCB4 UCSF GRCh37 7 87051535 87051535 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 7 44 0 ENST00000265723.4:c.2218G>A p.Gly740Arg p.G740R ENST00000265723 NM_000443.3 740 Gga/Aga 0 +ABCC12 UCSF GRCh37 16 48138152 48138152 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 206 78 126 0 ENST00000311303.3:c.2801T>G p.Phe934Cys p.F934C ENST00000311303 NM_033226.2 934 tTt/tGt 0 +ABCF3 UCSF GRCh37 3 183906749 183906749 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 33 56 0 ENST00000429586.2:c.950C>T p.Thr317Ile p.T317I ENST00000429586 NM_018358.2 317 aCc/aTc 0 +ABHD12 UCSF GRCh37 20 25304020 25304020 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 80 38 74 0 ENST00000339157.5:c.363T>C p.Gly121= p.G121= ENST00000339157 NM_001042472.2 121 ggT/ggC 0 +ABHD16B UCSF GRCh37 20 62493648 62493648 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 15 9 0 ENST00000369916.3:c.755C>T p.Thr252Met p.T252M ENST00000369916 NM_080622.3 252 aCg/aTg 0 +ABHD6 UCSF GRCh37 3 58242354 58242354 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 132 36 66 0 ENST00000295962.4:c.41G>A p.Gly14Asp p.G14D ENST00000295962 NM_020676.5 14 gGc/gAc 0 +ABI3 UCSF GRCh37 17 47297537 47297537 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 5 12 0 ENST00000225941.1:c.651C>T p.Ala217= p.A217= ENST00000225941 NM_016428.2 217 gcC/gcT 0 +ACACB UCSF GRCh37 12 109679082 109679082 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 163 66 79 0 ENST00000338432.7:c.5018G>A p.Gly1673Glu p.G1673E ENST00000338432 1673 gGa/gAa 0 +ACACB UCSF GRCh37 12 109650679 109650679 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 128 37 84 0 ENST00000338432.7:c.3288G>A p.Gln1096= p.Q1096= ENST00000338432 1096 caG/caA 0 +ACAD10 UCSF GRCh37 12 112167638 112167638 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 14 49 0 ENST00000313698.4:c.1272C>T p.Thr424= p.T424= ENST00000313698 NM_025247.5 424 acC/acT 0 +ACADVL UCSF GRCh37 17 7125571 7125571 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 41 86 0 ENST00000356839.5:c.828G>A p.Lys276= p.K276= ENST00000356839 NM_001270448.1 276 aaG/aaA 0 +ACAN UCSF GRCh37 15 89390536 89390536 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 12 10 0 ENST00000439576.2:c.1492C>T p.Gln498Ter p.Q498* ENST00000439576 NM_013227.3 498 Cag/Tag 0 +ACAN UCSF GRCh37 15 89395258 89395258 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 30 53 0 ENST00000439576.2:c.2260C>T p.Leu754= p.L754= ENST00000439576 NM_013227.3 754 Ctg/Ttg 0 +ACAN UCSF GRCh37 15 89416168 89416168 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 28 54 0 ENST00000439576.2:c.7245C>T p.Asp2415= p.D2415= ENST00000439576 NM_013227.3 2415 gaC/gaT 0 +ACCN3 UCSF GRCh37 7 150747871 150747871 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 24 26 0 ENST00000349064.5:c.840C>T p.Gly280= p.G280= ENST00000349064 NM_004769.3 280 ggC/ggT 0 +ACCN4 UCSF GRCh37 2 220379918 220379918 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 49 24 0 ENST00000347842.3:c.853C>T p.Pro285Ser p.P285S ENST00000347842 NM_182847.2 285 Cca/Tca 0 +ACE2 UCSF GRCh37 X 15599355 15599355 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 39 74 146 0 ENST00000252519.3:c.1059G>A p.Lys353= p.K353= ENST00000252519 353 aaG/aaA 0 +ACO2 UCSF GRCh37 22 41903918 41903918 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 17 32 22 0 ENST00000216254.4:c.297G>A p.Gln99= p.Q99= ENST00000216254 NM_001098.2 99 caG/caA 0 +ACOT12 UCSF GRCh37 5 80626242 80626242 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 21 71 0 ENST00000307624.3:c.1639C>T p.Pro547Ser p.P547S ENST00000307624 NM_130767.2 547 Cct/Tct 0 +ACP6 UCSF GRCh37 1 147126370 147126370 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 37 76 0 ENST00000369238.6:c.719G>A p.Gly240Asp p.G240D ENST00000369238 NM_016361.4 240 gGc/gAc 0 +ACSL6 UCSF GRCh37 5 131323748 131323748 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 59 120 0 ENST00000379240.1:c.749C>T p.Ala250Val p.A250V ENST00000379240 250 gCc/gTc 0 +ACTN4 UCSF GRCh37 19 39218666 39218666 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 22 10 0 ENST00000252699.2:c.2418G>A p.Gln806= p.Q806= ENST00000252699 NM_004924.4 806 caG/caA 0 +ACTR1B UCSF GRCh37 2 98275454 98275454 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 64 71 0 ENST00000289228.5:c.328C>T p.Leu110Phe p.L110F ENST00000289228 NM_005735.3 110 Ctc/Ttc 0 +ACTR3B UCSF GRCh37 7 152497666 152497666 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 266 87 208 0 ENST00000256001.8:c.151G>A p.Val51Met p.V51M ENST00000256001 NM_020445.5 51 Gtg/Atg 0 +ACVR2A UCSF GRCh37 2 148657339 148657339 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 177 104 251 0 ENST00000241416.7:c.400C>T p.Pro134Ser p.P134S ENST00000241416 NM_001616.4 134 Cca/Tca 0 +ACVR2B UCSF GRCh37 3 38523998 38523998 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 7 19 0 ENST00000352511.4:c.1291G>A p.Val431Met p.V431M ENST00000352511 NM_001106.3 431 Gtg/Atg 0 +ADAM22 UCSF GRCh37 7 87762229 87762229 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 19 46 0 ENST00000265727.7:c.1040G>A p.Gly347Glu p.G347E ENST00000265727 347 gGg/gAg 0 +ADAM23 UCSF GRCh37 2 207426926 207426926 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 199 124 201 0 ENST00000264377.3:c.1255-1G>A p.X419_splice ENST00000264377 NM_003812.3 0 +ADAMTS12 UCSF GRCh37 5 33561169 33561169 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 60 84 0 ENST00000504830.1:c.4088G>A p.Arg1363His p.R1363H ENST00000504830 NM_030955.2 1363 cGt/cAt 0 +ADAMTS14 UCSF GRCh37 10 72520286 72520286 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 38 41 0 ENST00000373207.1:c.3349C>T p.Pro1117Ser p.P1117S ENST00000373207 NM_080722.3 1117 Cct/Tct 0 +ADAMTS9 UCSF GRCh37 3 64666961 64666961 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 20 37 0 ENST00000498707.1:c.595G>A p.Glu199Lys p.E199K ENST00000498707 NM_182920.1 199 Gaa/Aaa 0 +ADAMTSL3 UCSF GRCh37 15 84611718 84611718 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 33 32 0 ENST00000286744.5:c.2374G>A p.Asp792Asn p.D792N ENST00000286744 NM_207517.2 792 Gat/Aat 0 +ADCY10 UCSF GRCh37 1 167815414 167815414 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 61 109 0 ENST00000367851.4:c.2525C>T p.Thr842Ile p.T842I ENST00000367851 NM_018417.4 842 aCt/aTt 0 +ADCY2 UCSF GRCh37 5 7717290 7717290 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 32 47 0 ENST00000338316.4:c.1643G>A p.Arg548Lys p.R548K ENST00000338316 NM_020546.2 548 aGa/aAa 0 +ADCY7 UCSF GRCh37 16 50348926 50348926 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 139 136 104 0 ENST00000254235.3:c.2973C>T p.Gly991= p.G991= ENST00000254235 NM_001114.3 991 ggC/ggT 0 +ADD2 UCSF GRCh37 2 70904949 70904949 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 47 58 0 ENST00000264436.4:c.1444C>T p.Pro482Ser p.P482S ENST00000264436 NM_001617.3 482 Cca/Tca 0 +ADORA1 UCSF GRCh37 1 203134985 203134985 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 40 53 0 ENST00000309502.3:c.938C>T p.Pro313Leu p.P313L ENST00000309502 313 cCt/cTt 0 +ADRA2B UCSF GRCh37 2 96781752 96781752 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 21 8 0 ENST00000409345.3:c.137C>T p.Pro46Leu p.P46L ENST00000409345 NM_000682.5 46 cCt/cTt 0 +AEBP1 UCSF GRCh37 7 44149871 44149871 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 22 35 0 ENST00000223357.3:c.1326G>A p.Gln442= p.Q442= ENST00000223357 NM_001129.4 442 caG/caA 0 +AFF3 UCSF GRCh37 2 100210059 100210059 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 88 43 0 ENST00000409236.2:c.2064C>T p.Tyr688= p.Y688= ENST00000409236 688 taC/taT 0 +AGAP11 UCSF GRCh37 10 88768200 88768200 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 115 270 1 ENST00000433214.2:n.1395G>A *465* ENST00000433214 0 +AGBL2 UCSF GRCh37 11 47707481 47707481 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 53 139 0 ENST00000525123.1:c.1752C>T p.Val584= p.V584= ENST00000525123 NM_024783.3 584 gtC/gtT 0 +AGK UCSF GRCh37 7 141352686 141352686 + splice_region_variant,intron_variant,non_coding_transcript_variant Splice_Region SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 171 57 74 0 ENST00000467537.1:n.268-3T>G p.X90_splice ENST00000467537 0 +AGL UCSF GRCh37 1 100316681 100316681 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 52 71 0 ENST00000294724.4:c.82+1G>A p.X28_splice ENST00000294724 NM_000028.2 0 +AGPAT2 UCSF GRCh37 9 139571054 139571054 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 30 20 0 ENST00000371696.2:c.571C>T p.Leu191= p.L191= ENST00000371696 NM_006412.3 191 Ctg/Ttg 0 +AHRR UCSF GRCh37 5 434260 434260 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 34 24 0 ENST00000505113.1:c.1417C>T p.Arg473Trp p.R473W ENST00000505113 NM_001242412.1 473 Cgg/Tgg 0 +AHRR UCSF GRCh37 5 427752 427752 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 51 33 0 ENST00000505113.1:c.721-170G>A *241* ENST00000505113 NM_001242412.1 0 +AHSA1 UCSF GRCh37 14 77929093 77929093 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 29 66 0 ENST00000216479.3:c.463C>T p.Leu155Phe p.L155F ENST00000216479 NM_012111.2 155 Ctc/Ttc 0 +AIFM1 UCSF GRCh37 X 129281803 129281803 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 76 155 0 ENST00000287295.3:c.398C>T p.Pro133Leu p.P133L ENST00000287295 NM_004208.3 133 cCt/cTt 0 +AIPL1 UCSF GRCh37 17 6329947 6329947 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 23 18 0 ENST00000381129.3:c.772C>T p.Arg258Trp p.R258W ENST00000381129 NM_014336.3 258 Cgg/Tgg 0 +AIPL1 UCSF GRCh37 17 6329972 6329972 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 32 21 0 ENST00000381129.3:c.747G>A p.Val249= p.V249= ENST00000381129 NM_014336.3 249 gtG/gtA 0 +AK7 UCSF GRCh37 14 96953269 96953269 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 14 42 0 ENST00000267584.4:c.2009G>A p.Arg670Lys p.R670K ENST00000267584 NM_152327.3 670 aGa/aAa 0 +AKAP8 UCSF GRCh37 19 15483797 15483797 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 19 11 0 ENST00000269701.2:c.726G>A p.Arg242= p.R242= ENST00000269701 NM_005858.3 242 cgG/cgA 0 +AKD1 UCSF GRCh37 6 109835578 109835578 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 35 94 0 ENST00000424296.2:c.4128C>T p.Ile1376= p.I1376= ENST00000424296 NM_001145128.2 1376 atC/atT 0 +AKNA UCSF GRCh37 9 117119143 117119143 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 48 54 0 ENST00000307564.4:c.2846G>A p.Ser949Asn p.S949N ENST00000307564 NM_030767.4 949 aGc/aAc 0 +AKNAD1 UCSF GRCh37 1 109395078 109395078 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 80 88 0 ENST00000370001.3:c.209C>T p.Thr70Ile p.T70I ENST00000370001 NM_152763.4 70 aCc/aTc 0 +AKNAD1 UCSF GRCh37 1 109385874 109385874 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 44 54 0 ENST00000370001.3:c.1261C>T p.Gln421Ter p.Q421* ENST00000370001 NM_152763.4 421 Cag/Tag 0 +ALCAM UCSF GRCh37 3 105260490 105260490 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 17 60 0 ENST00000306107.5:c.872G>A p.Gly291Glu p.G291E ENST00000306107 NM_001627.3 291 gGa/gAa 0 +ALDH4A1 UCSF GRCh37 1 19202840 19202840 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 31 31 0 ENST00000290597.5:c.1307G>A p.Ser436Asn p.S436N ENST00000290597 NM_170726.2 436 aGc/aAc 0 +ALDH4A1 UCSF GRCh37 1 19204034 19204034 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 19 9 0 ENST00000290597.5:c.1013G>A p.Arg338His p.R338H ENST00000290597 NM_170726.2 338 cGc/cAc 0 +ALG11 UCSF GRCh37 13 52598626 52598626 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 70 93 0 ENST00000521508.1:c.760G>A p.Val254Ile p.V254I ENST00000521508 NM_001004127.2 254 Gtc/Atc 0 +ALKBH3 UCSF GRCh37 11 43904246 43904246 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 8 26 36 0 ENST00000302708.4:c.44C>T p.Ala15Val p.A15V ENST00000302708 NM_139178.3 15 gCt/gTt 0 +ALMS1 UCSF GRCh37 2 73675096 73675096 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 20 38 66 0 ENST00000264448.6:c.1439C>T p.Thr480Ile p.T480I ENST00000264448 NM_015120.4 480 aCt/aTt 0 +ALOX15B UCSF GRCh37 17 7948887 7948887 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 25 35 0 ENST00000380183.4:c.1083C>T p.Arg361= p.R361= ENST00000380183 NM_001141.2 361 cgC/cgT 0 +ALOXE3 UCSF GRCh37 17 8020099 8020099 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 20 42 0 ENST00000448843.2:c.347G>A p.Gly116Glu p.G116E ENST00000448843 NM_021628.2 116 gGa/gAa 0 +ALOXE3 UCSF GRCh37 17 8014809 8014809 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 27 71 0 ENST00000448843.2:c.825G>A p.Gly275= p.G275= ENST00000448843 NM_021628.2 275 ggG/ggA 0 +ALPPL2 UCSF GRCh37 2 233274294 233274294 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 9 12 12 0 ENST00000295453.3:c.1311G>A p.Glu437= p.E437= ENST00000295453 NM_031313.2 437 gaG/gaA 0 +ALS2CR11 UCSF GRCh37 2 202359129 202359129 + intron_variant Intron SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 167 92 170 0 ENST00000286195.3:c.1581+1489G>A *527* ENST00000286195 NM_152525.5 0 +ALS2CR11 UCSF GRCh37 2 202359204 202359204 + intron_variant Intron SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 142 69 145 0 ENST00000286195.3:c.1581+1414T>G *527* ENST00000286195 NM_152525.5 0 +AMOTL2 UCSF GRCh37 3 134089737 134089737 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 18 23 0 ENST00000422605.2:c.539C>T p.Ser180Phe p.S180F ENST00000422605 180 tCc/tTc 0 +AMY2B UCSF GRCh37 1 104115845 104115845 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 217 135 218 0 ENST00000361355.4:c.476G>A p.Gly159Glu p.G159E ENST00000361355 NM_020978.4 159 gGa/gAa 0 +ANAPC5 UCSF GRCh37 12 121746438 121746438 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 108 40 109 0 ENST00000261819.3:c.2113G>A p.Asp705Asn p.D705N ENST00000261819 NM_016237.4 705 Gac/Aac 0 +ANK2 UCSF GRCh37 4 114294449 114294449 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 38 110 0 ENST00000357077.4:c.11703G>A p.Arg3901= p.R3901= ENST00000357077 NM_001148.4 3901 agG/agA 0 +ANKFY1 UCSF GRCh37 17 4074130 4074130 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 22 34 0 ENST00000341657.4:c.3165G>A p.Gly1055= p.G1055= ENST00000341657 NM_016376.3 1055 ggG/ggA 0 +ANKHD1 UCSF GRCh37 5 139908515 139908515 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 73 127 0 ENST00000360839.2:c.5984C>T p.Thr1995Ile p.T1995I ENST00000360839 NM_017747.2 1995 aCt/aTt 0 +ANKLE2 UCSF GRCh37 12 133324426 133324426 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 47 59 0 ENST00000357997.5:c.1222G>A p.Asp408Asn p.D408N ENST00000357997 NM_015114.1 408 Gac/Aac 0 +ANKRD1 UCSF GRCh37 10 92680047 92680047 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 82 157 0 ENST00000371697.3:c.86G>A p.Arg29Lys p.R29K ENST00000371697 NM_014391.2 29 aGa/aAa 0 +ANKRD11 UCSF GRCh37 16 89351166 89351166 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 108 42 59 0 ENST00000301030.4:c.1784G>A p.Arg595Lys p.R595K ENST00000301030 NM_001256183.1 595 aGg/aAg 0 +ANKRD11 UCSF GRCh37 16 89347886 89347886 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 255 96 39 0 ENST00000301030.4:c.5064C>T p.Val1688= p.V1688= ENST00000301030 NM_001256183.1 1688 gtC/gtT 0 +ANKRD11 UCSF GRCh37 16 89371699 89371699 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 112 29 20 0 ENST00000301030.4:c.141C>T p.Gly47= p.G47= ENST00000301030 NM_001256183.1 47 ggC/ggT 0 +ANKRD11 UCSF GRCh37 16 89341222 89341222 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 46 40 0 ENST00000301030.4:c.7713G>A p.Gln2571= p.Q2571= ENST00000301030 NM_001256183.1 2571 caG/caA 0 +ANKRD13A UCSF GRCh37 12 110456212 110456212 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 40 51 0 ENST00000261739.4:c.463C>T p.Leu155= p.L155= ENST00000261739 NM_033121.1 155 Ctg/Ttg 0 +ANKRD24 UCSF GRCh37 19 4216973 4216973 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 34 29 0 ENST00000318934.4:c.1816G>A p.Val606Ile p.V606I ENST00000318934 606 Gtc/Atc 0 +ANKRD46 UCSF GRCh37 8 101540115 101540115 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 33 75 0 ENST00000520552.1:c.428C>T p.Thr143Ile p.T143I ENST00000520552 NM_001270379.1 143 aCc/aTc 0 +ANKRD6 UCSF GRCh37 6 90333154 90333154 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 12 27 0 ENST00000339746.4:c.923C>T p.Pro308Leu p.P308L ENST00000339746 NM_001242809.1 308 cCc/cTc 0 +ANLN UCSF GRCh37 7 36455449 36455449 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 195 70 100 0 ENST00000265748.2:c.1478C>T p.Thr493Ile p.T493I ENST00000265748 NM_018685.2 493 aCc/aTc 0 +ANO10 UCSF GRCh37 3 43647213 43647213 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P05_Rec Untested WXS Illumina HiSeq 10 0 ENST00000292246.3:c.132delA p.Asp45MetfsTer12 p.D45Mfs*12 ENST00000292246 NM_018075.3 44 aaA/aa 0 +ANO2 UCSF GRCh37 12 5963241 5963241 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 143 76 141 0 ENST00000356134.5:c.589G>A p.Glu197Lys p.E197K ENST00000356134 197 Gaa/Aaa 0 +AOC3 UCSF GRCh37 17 41006513 41006513 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 22 30 0 ENST00000308423.2:c.1649C>T p.Ala550Val p.A550V ENST00000308423 NM_003734.3 550 gCt/gTt 0 +AP1AR UCSF GRCh37 4 113186173 113186173 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 108 55 94 0 ENST00000274000.5:c.390G>A p.Arg130= p.R130= ENST00000274000 NM_018569.4 130 agG/agA 0 +AP1M1 UCSF GRCh37 19 16314331 16314331 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 32 40 0 ENST00000291439.3:c.104C>T p.Pro35Leu p.P35L ENST00000291439 NM_032493.3 35 cCc/cTc 0 +APCDD1 UCSF GRCh37 18 10485656 10485656 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 32 45 0 ENST00000355285.5:c.972C>T p.Gly324= p.G324= ENST00000355285 NM_153000.4 324 ggC/ggT 0 +APCDD1L UCSF GRCh37 20 57042262 57042262 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 15 12 0 ENST00000371149.3:c.641G>A p.Arg214Gln p.R214Q ENST00000371149 NM_153360.1 214 cGg/cAg 0 +APEX2 UCSF GRCh37 X 55033194 55033194 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 51 20 30 0 ENST00000374987.3:c.883C>T p.Leu295= p.L295= ENST00000374987 NM_014481.3 295 Ctg/Ttg 0 +APOA2 UCSF GRCh37 1 161192746 161192746 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 32 63 0 ENST00000367990.3:c.147G>A p.Met49Ile p.M49I ENST00000367990 NM_001643.1 49 atG/atA 0 +APOB UCSF GRCh37 2 21232717 21232717 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 58 119 0 ENST00000233242.1:c.7023C>T p.Val2341= p.V2341= ENST00000233242 NM_000384.2 2341 gtC/gtT 0 +APOC3 UCSF GRCh37 11 116701560 116701560 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 28 11 14 0 ENST00000227667.3:c.127G>A p.Ala43Thr p.A43T ENST00000227667 NM_000040.1 43 Gcc/Acc 0 +APOF UCSF GRCh37 12 56755627 56755627 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 41 71 0 ENST00000398189.3:c.363G>A p.Gln121= p.Q121= ENST00000398189 NM_001638.2 121 caG/caA 0 +APOL2 UCSF GRCh37 22 36624040 36624040 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 22 65 0 ENST00000249066.6:c.424G>A p.Glu142Lys p.E142K ENST00000249066 NM_145637.1 142 Gaa/Aaa 0 +APOL5 UCSF GRCh37 22 36123218 36123218 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 30 41 0 ENST00000249044.2:c.1103G>A p.Gly368Glu p.G368E ENST00000249044 NM_030642.1 368 gGa/gAa 0 +APTX UCSF GRCh37 9 32987663 32987663 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 118 59 128 0 ENST00000379819.1:c.404G>A p.Ser135Asn p.S135N ENST00000379819 135 aGt/aAt 0 +AQP12B UCSF GRCh37 2 241622083 241622083 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 12 48 23 0 ENST00000407834.3:c.172G>A p.Val58Ile p.V58I ENST00000407834 NM_001102467.1 58 Gtc/Atc 0 +AR UCSF GRCh37 X 66863097 66863097 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 34 65 0 ENST00000374690.3:c.1617-1G>A p.X539_splice ENST00000374690 NM_000044.3 0 +ARAP1 UCSF GRCh37 11 72415292 72415292 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 37 9 0 ENST00000393609.3:c.1897C>T p.Pro633Ser p.P633S ENST00000393609 NM_001040118.2 633 Ccc/Tcc 0 +ARAP3 UCSF GRCh37 5 141033718 141033718 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 7 17 38 0 ENST00000239440.4:c.4434G>A p.Arg1478= p.R1478= ENST00000239440 NM_022481.5 1478 cgG/cgA 0 +ARC UCSF GRCh37 8 143694837 143694837 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 38 37 0 ENST00000356613.2:c.796G>A p.Glu266Lys p.E266K ENST00000356613 NM_015193.4 266 Gag/Aag 0 +ARFGEF1 UCSF GRCh37 8 68179357 68179357 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 42 77 0 ENST00000262215.3:c.1781G>A p.Gly594Asp p.G594D ENST00000262215 NM_006421.4 594 gGc/gAc 0 +ARGLU1 UCSF GRCh37 13 107211856 107211856 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 28 168 0 ENST00000400198.3:c.497G>A p.Arg166His p.R166H ENST00000400198 NM_018011.3 166 cGc/cAc 0 +ARHGAP20 UCSF GRCh37 11 110450171 110450171 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 60 95 0 ENST00000260283.4:c.3499G>A p.Glu1167Lys p.E1167K ENST00000260283 NM_020809.3 1167 Gag/Aag 0 +ARHGAP20 UCSF GRCh37 11 110453055 110453055 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 142 75 125 0 ENST00000260283.4:c.1710G>A p.Glu570= p.E570= ENST00000260283 NM_020809.3 570 gaG/gaA 0 +ARHGEF10L UCSF GRCh37 1 17948377 17948377 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 59 48 30 0 ENST00000361221.3:c.961C>G p.Leu321Val p.L321V ENST00000361221 NM_018125.3 321 Ctg/Gtg 0 +ARHGEF15 UCSF GRCh37 17 8219385 8219385 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 14 14 0 ENST00000361926.3:c.1623C>T p.Leu541= p.L541= ENST00000361926 NM_173728.3 541 ctC/ctT 0 +ARHGEF18 UCSF GRCh37 19 7535023 7535023 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 55 46 0 ENST00000359920.6:c.3361C>T p.Pro1121Ser p.P1121S ENST00000359920 NM_001130955.1 1121 Ccc/Tcc 0 +ARHGEF2 UCSF GRCh37 1 155935434 155935434 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 46 49 0 ENST00000361247.4:c.458C>T p.Thr153Ile p.T153I ENST00000361247 NM_001162384.1 153 aCc/aTc 0 +ARHGEF25 UCSF GRCh37 12 58008323 58008323 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 32 50 0 ENST00000286494.4:c.751G>A p.Val251Met p.V251M ENST00000286494 NM_182947.3 251 Gtg/Atg 0 +ARHGEF40 UCSF GRCh37 14 21542414 21542414 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 37 47 0 ENST00000298694.4:c.525G>A p.Arg175= p.R175= ENST00000298694 NM_001278529.1 175 cgG/cgA 0 +ARID1A UCSF GRCh37 1 27092831 27092831 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 42 70 0 ENST00000324856.7:c.2852G>A p.Gly951Asp p.G951D ENST00000324856 NM_006015.4 951 gGt/gAt 0 +ARID1B UCSF GRCh37 6 157522031 157522031 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 47 27 0 ENST00000350026.5:c.4264C>T p.Pro1422Ser p.P1422S ENST00000350026 NM_017519.2 1422 Ccg/Tcg 0 +ARL4A UCSF GRCh37 7 12728105 12728105 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 67 154 0 ENST00000356797.3:c.226G>A p.Val76Ile p.V76I ENST00000356797 76 Gta/Ata 0 +ARL6 UCSF GRCh37 3 97499033 97499033 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 49 44 0 ENST00000335979.2:c.154G>A p.Gly52Arg p.G52R ENST00000335979 NM_032146.4 52 Gga/Aga 0 +ARMC4 UCSF GRCh37 10 28225673 28225673 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 112 61 152 1 ENST00000305242.5:c.2234G>A p.Ser745Asn p.S745N ENST00000305242 NM_018076.2 745 aGc/aAc 0 +ARMCX5 UCSF GRCh37 X 101857642 101857642 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 82 136 0 ENST00000246174.2:c.573G>A p.Glu191= p.E191= ENST00000246174 NM_001168480.1 191 gaG/gaA 0 +ARNT UCSF GRCh37 1 150814899 150814899 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 25 83 0 ENST00000358595.5:c.272+1G>A p.X91_splice ENST00000358595 NM_178427.2 0 +ARPP21 UCSF GRCh37 3 35748507 35748507 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 21 65 0 ENST00000187397.4:c.728G>A p.Gly243Asp p.G243D ENST00000187397 NM_016300.4 243 gGt/gAt 0 +ARRDC5 UCSF GRCh37 19 4902759 4902759 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 60 124 0 ENST00000381781.2:c.121G>A p.Val41Met p.V41M ENST00000381781 NM_001080523.1 41 Gtg/Atg 0 +ARRDC5 UCSF GRCh37 19 4891544 4891544 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 68 77 0 ENST00000381781.2:c.543C>T p.Asn181= p.N181= ENST00000381781 NM_001080523.1 181 aaC/aaT 0 +ARSH UCSF GRCh37 X 2942141 2942141 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 11 22 27 0 ENST00000381130.2:c.981C>T p.His327= p.H327= ENST00000381130 NM_001011719.1 327 caC/caT 0 +ASAH1 UCSF GRCh37 8 17915063 17915063 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 14 23 0 ENST00000262097.6:c.1168G>A p.Asp390Asn p.D390N ENST00000262097 NM_177924.3 390 Gac/Aac 0 +ASB6 UCSF GRCh37 9 132400594 132400594 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 37 30 0 ENST00000277458.4:c.741G>A p.Leu247= p.L247= ENST00000277458 NM_017873.3 247 ctG/ctA 0 +ASCC2 UCSF GRCh37 22 30210654 30210654 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 21 33 0 ENST00000307790.3:c.712C>T p.Pro238Ser p.P238S ENST00000307790 NM_032204.4 238 Cct/Tct 0 +ASPH UCSF GRCh37 8 62430118 62430118 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 39 62 0 ENST00000379454.4:c.2095G>A p.Gly699Ser p.G699S ENST00000379454 NM_004318.3 699 Ggc/Agc 0 +ASPHD2 UCSF GRCh37 22 26830109 26830109 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 34 39 0 ENST00000215906.5:c.528G>A p.Thr176= p.T176= ENST00000215906 NM_020437.4 176 acG/acA 0 +ASPM UCSF GRCh37 1 197072633 197072633 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 64 117 0 ENST00000367409.4:c.5748G>A p.Gln1916= p.Q1916= ENST00000367409 NM_018136.4 1916 caG/caA 0 +ASXL1 UCSF GRCh37 20 31021696 31021696 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 85 86 0 ENST00000375687.4:c.1695G>A p.Glu565= p.E565= ENST00000375687 NM_015338.5 565 gaG/gaA 0 +ATF7 UCSF GRCh37 12 53931335 53931335 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 94 60 159 0 ENST00000548446.2:c.299C>T p.Ala100Val p.A100V ENST00000548446 100 gCt/gTt 0 +ATG13 UCSF GRCh37 11 46690417 46690417 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 28 57 0 ENST00000359513.4:c.1304G>A p.Gly435Asp p.G435D ENST00000359513 435 gGc/gAc 0 +ATG2A UCSF GRCh37 11 64677367 64677367 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 29 10 0 ENST00000377264.3:c.1893G>A p.Gln631= p.Q631= ENST00000377264 NM_015104.2 631 caG/caA 0 +ATM UCSF GRCh37 11 108155178 108155178 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 57 33 0 ENST00000278616.4:c.3971G>A p.Ser1324Asn p.S1324N ENST00000278616 NM_000051.3 1324 aGt/aAt 0 +ATN1 UCSF GRCh37 12 7045938 7045939 + protein_altering_variant In_Frame_Ins INS - - AGCAGCAGC NOVEL P05_Rec Untested WXS Illumina HiSeq 7 0 ENST00000356654.4:c.1508_1509insAGCAGCAGC p.His503delinsGlnAlaAlaAla p.H503delinsQAAA ENST00000356654 NM_001007026.1 503 cat/caAGCAGCAGCt 0 +ATP11A UCSF GRCh37 13 113512565 113512565 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 44 55 0 ENST00000375645.3:c.2628C>T p.Tyr876= p.Y876= ENST00000375645 NM_015205.2 876 taC/taT 0 +ATP13A4 UCSF GRCh37 3 193183851 193183851 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 145 69 145 0 ENST00000342695.4:c.1235G>A p.Gly412Glu p.G412E ENST00000342695 NM_032279.2 412 gGg/gAg 0 +ATP13A4 UCSF GRCh37 3 193166011 193166011 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 30 80 0 ENST00000342695.4:c.2136G>A p.Arg712= p.R712= ENST00000342695 NM_032279.2 712 agG/agA 0 +ATP1A2 UCSF GRCh37 1 160094966 160094966 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 30 43 0 ENST00000361216.3:c.671C>T p.Thr224Ile p.T224I ENST00000361216 NM_000702.3 224 aCc/aTc 0 +ATP1B4 UCSF GRCh37 X 119500574 119500574 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 49 63 0 ENST00000218008.3:c.258G>A p.Leu86= p.L86= ENST00000218008 NM_001142447.2 86 ttG/ttA 0 +ATP2A1 UCSF GRCh37 16 28912191 28912191 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 39 46 0 ENST00000357084.3:c.2054C>T p.Ser685Phe p.S685F ENST00000357084 NM_173201.3 685 tCc/tTc 0 +ATP2B1 UCSF GRCh37 12 89984838 89984838 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 66 117 0 ENST00000428670.3:c.3586C>T p.Leu1196Phe p.L1196F ENST00000428670 1196 Ctt/Ttt 0 +ATP2B2 UCSF GRCh37 3 10382388 10382388 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 37 37 0 ENST00000352432.4:c.2918G>A p.Gly973Asp p.G973D ENST00000352432 973 gGc/gAc 0 +ATP2B4 UCSF GRCh37 1 203668793 203668793 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 136 80 118 0 ENST00000357681.5:c.597C>T p.Ile199= p.I199= ENST00000357681 NM_001684.4 199 atC/atT 0 +ATP5J2-PTCD1 UCSF GRCh37 7 99032460 99032460 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 242 61 111 0 ENST00000292478.4:c.406C>T p.Pro136Ser p.P136S ENST00000292478 NM_015545.3 136 Ccg/Tcg 0 +ATP7B UCSF GRCh37 13 52544773 52544773 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 28 61 83 0 ENST00000242839.4:c.1398C>T p.Leu466= p.L466= ENST00000242839 NM_000053.3 466 ctC/ctT 0 +ATP8B4 UCSF GRCh37 15 50288947 50288947 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 22 26 0 ENST00000284509.6:c.516C>T p.Asn172= p.N172= ENST00000284509 NM_024837.3 172 aaC/aaT 0 +ATP9A UCSF GRCh37 20 50273508 50273508 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 21 23 0 ENST00000338821.5:c.1475G>A p.Cys492Tyr p.C492Y ENST00000338821 NM_006045.1 492 tGc/tAc 0 +ATRN UCSF GRCh37 20 3624813 3624813 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 53 106 0 ENST00000262919.5:c.4063C>T p.Pro1355Ser p.P1355S ENST00000262919 NM_139321.2 1355 Ccc/Tcc 0 +ATRX UCSF GRCh37 X 76875979 76875979 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 49 48 54 0 ENST00000373344.5:c.5156A>G p.Asp1719Gly p.D1719G ENST00000373344 NM_000489.3 1719 gAt/gGt 0 +ATXN3L UCSF GRCh37 X 13338003 13338003 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 94 192 0 ENST00000380622.2:c.51C>T p.His17= p.H17= ENST00000380622 NM_001135995.1 17 caC/caT 0 +ATXN7L2 UCSF GRCh37 1 110033657 110033657 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 65 40 0 ENST00000369870.3:c.1472G>A p.Arg491Lys p.R491K ENST00000369870 NM_153340.4 491 aGa/aAa 0 +ATXN7L2 UCSF GRCh37 1 110031543 110031543 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 49 51 0 ENST00000369870.3:c.858G>A p.Lys286= p.K286= ENST00000369870 NM_153340.4 286 aaG/aaA 0 +AUH UCSF GRCh37 9 93979608 93979608 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 14 48 0 ENST00000375731.4:c.845G>A p.Gly282Glu p.G282E ENST00000375731 NM_001698.2 282 gGa/gAa 0 +AUTS2 UCSF GRCh37 7 70254767 70254767 + synonymous_variant Silent SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 96 51 70 0 ENST00000342771.4:c.2565T>C p.Pro855= p.P855= ENST00000342771 NM_015570.2 855 ccT/ccC 0 +AVL9 UCSF GRCh37 7 32584392 32584392 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 9 28 0 ENST00000318709.4:c.300+1G>A p.X100_splice ENST00000318709 NM_015060.1 0 +AVL9 UCSF GRCh37 7 32598240 32598240 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 26 62 0 ENST00000318709.4:c.679G>A p.Gly227Ser p.G227S ENST00000318709 NM_015060.1 227 Ggc/Agc 0 +AXIN1 UCSF GRCh37 16 343703 343703 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 23 44 0 ENST00000262320.3:c.1971G>A p.Arg657= p.R657= ENST00000262320 NM_003502.3 657 agG/agA 0 +AZI1 UCSF GRCh37 17 79164773 79164773 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 43 28 0 ENST00000269392.4:c.2886G>A p.Glu962= p.E962= ENST00000269392 NM_014984.2 962 gaG/gaA 0 +AZI1 UCSF GRCh37 17 79193782 79193782 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 38 34 0 ENST00000269392.4:c.75C>T p.Leu25= p.L25= ENST00000269392 NM_014984.2 25 ctC/ctT 0 +B3GALT4 UCSF GRCh37 6 33246072 33246072 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 46 53 0 ENST00000451237.1:c.876C>T p.Val292= p.V292= ENST00000451237 NM_003782.3 292 gtC/gtT 0 +B4GALT4 UCSF GRCh37 3 118945752 118945752 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 12 39 0 ENST00000359213.3:c.390C>T p.His130= p.H130= ENST00000359213 NM_212543.1 130 caC/caT 0 +BACE1 UCSF GRCh37 11 117165989 117165989 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 36 53 0 ENST00000313005.6:c.425G>A p.Gly142Asp p.G142D ENST00000313005 NM_138971.3 142 gGc/gAc 0 +BAD UCSF GRCh37 11 64051683 64051683 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 65 58 25 0 ENST00000309032.3:c.158A>G p.Glu53Gly p.E53G ENST00000309032 NM_032989.2 53 gAg/gGg 0 +BAG3 UCSF GRCh37 10 121436297 121436297 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 34 67 0 ENST00000369085.3:c.1231G>A p.Gly411Arg p.G411R ENST00000369085 NM_004281.3 411 Gga/Aga 0 +BAHCC1 UCSF GRCh37 17 79426522 79426522 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 30 30 0 ENST00000307745.7:c.5797G>A p.Val1933Ile p.V1933I ENST00000307745 1933 Gtt/Att 0 +BAI3 UCSF GRCh37 6 69640470 69640470 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 25 17 24 0 ENST00000370598.1:c.777T>G p.Asp259Glu p.D259E ENST00000370598 NM_001704.2 259 gaT/gaG 0 +BAIAP2L1 UCSF GRCh37 7 97946557 97946557 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 216 74 147 0 ENST00000005260.8:c.460C>T p.Leu154Phe p.L154F ENST00000005260 NM_018842.4 154 Ctc/Ttc 0 +BAZ1B UCSF GRCh37 7 72892854 72892854 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 27 48 0 ENST00000339594.4:c.937C>T p.Pro313Ser p.P313S ENST00000339594 NM_032408.3 313 Cca/Tca 0 +BAZ2B UCSF GRCh37 2 160205734 160205734 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 22 41 0 ENST00000392783.2:c.4921G>A p.Val1641Ile p.V1641I ENST00000392783 NM_013450.2 1641 Gtt/Att 0 +BAZ2B UCSF GRCh37 2 160295520 160295520 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 113 62 97 0 ENST00000392783.2:c.900G>A p.Gln300= p.Q300= ENST00000392783 NM_013450.2 300 caG/caA 0 +BBS10 UCSF GRCh37 12 76741297 76741297 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 31 47 0 ENST00000393262.3:c.468C>T p.Ile156= p.I156= ENST00000393262 NM_024685.3 156 atC/atT 0 +BCAM UCSF GRCh37 19 45314506 45314506 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 39 59 0 ENST00000270233.6:c.107C>T p.Ser36Phe p.S36F ENST00000270233 NM_005581.4 36 tCt/tTt 0 +BCL11A UCSF GRCh37 2 60688616 60688616 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 25 15 0 ENST00000335712.6:c.1431C>T p.Asn477= p.N477= ENST00000335712 NM_022893.3 477 aaC/aaT 0 +BCL7C UCSF GRCh37 16 30905182 30905182 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 13 13 0 ENST00000215115.4:c.84C>T p.Val28= p.V28= ENST00000215115 NM_004765.2 28 gtC/gtT 0 +BCL9 UCSF GRCh37 1 147091456 147091456 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 53 60 0 ENST00000234739.3:c.1495G>A p.Asp499Asn p.D499N ENST00000234739 NM_004326.3 499 Gac/Aac 0 +BCMO1 UCSF GRCh37 16 81301516 81301516 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 24 31 0 ENST00000258168.2:c.623G>A p.Gly208Asp p.G208D ENST00000258168 NM_017429.2 208 gGc/gAc 0 +BCO2 UCSF GRCh37 11 112071473 112071473 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 47 102 0 ENST00000357685.5:c.1003G>A p.Val335Met p.V335M ENST00000357685 335 Gtg/Atg 0 +BCS1L UCSF GRCh37 2 219525867 219525867 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 59 81 0 ENST00000359273.3:c.157G>A p.Val53Ile p.V53I ENST00000359273 NM_001257344.1 53 Gtc/Atc 0 +BDKRB1 UCSF GRCh37 14 96731073 96731073 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.00092 P05_Rec Untested WXS Illumina HiSeq 113 41 102 0 ENST00000216629.6:c.1054C>T p.Arg352Trp p.R352W ENST00000216629 NM_000710.3 352 Cgg/Tgg 0 +BEND2 UCSF GRCh37 X 18183192 18183192 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 70 93 0 ENST00000380033.4:c.2337C>T p.Thr779= p.T779= ENST00000380033 NM_153346.4 779 acC/acT 0 +BEST2 UCSF GRCh37 19 12866441 12866441 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 12 54 0 ENST00000042931.1:c.727G>A p.Ala243Thr p.A243T ENST00000042931 NM_017682.2 243 Gca/Aca 0 +BHLHB9 UCSF GRCh37 X 102004592 102004592 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 112 125 0 ENST00000361229.4:c.669C>T p.Ala223= p.A223= ENST00000361229 NM_030639.2 223 gcC/gcT 0 +BIN2 UCSF GRCh37 12 51685495 51685495 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 20 25 0 ENST00000267012.4:c.1395C>T p.Val465= p.V465= ENST00000267012 NM_016293.2 465 gtC/gtT 0 +BIRC6 UCSF GRCh37 2 32743376 32743376 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 65 126 0 ENST00000421745.2:c.11405G>A p.Gly3802Glu p.G3802E ENST00000421745 NM_016252.3 3802 gGg/gAg 0 +BIRC7 UCSF GRCh37 20 61869967 61869967 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 55 50 49 0 ENST00000217169.3:c.577+1G>A p.X193_splice ENST00000217169 NM_139317.2 0 +BLOC1S1 UCSF GRCh37 12 56110721 56110721 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 50 84 0 ENST00000548925.1:c.150G>A p.Lys50= p.K50= ENST00000548925 50 aaG/aaA 0 +BOD1L UCSF GRCh37 4 13597562 13597562 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 148 70 115 0 ENST00000040738.5:c.8026G>A p.Val2676Met p.V2676M ENST00000040738 NM_148894.2 2676 Gtg/Atg 0 +BPGM UCSF GRCh37 7 134346582 134346582 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 38 67 0 ENST00000344924.3:c.323G>A p.Gly108Asp p.G108D ENST00000344924 NM_001724.4 108 gGt/gAt 0 +BPIFA1 UCSF GRCh37 20 31829249 31829249 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 66 146 0 ENST00000354297.4:c.640G>A p.Val214Ile p.V214I ENST00000354297 NM_130852.2 214 Gtc/Atc 0 +BPTF UCSF GRCh37 17 65908699 65908699 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 115 49 110 0 ENST00000321892.4:c.5077C>T p.Leu1693= p.L1693= ENST00000321892 1693 Ctg/Ttg 0 +BRD3 UCSF GRCh37 9 136913446 136913446 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 112 42 30 0 ENST00000303407.7:c.845G>A p.Gly282Asp p.G282D ENST00000303407 NM_007371.3 282 gGt/gAt 0 +BRI3BP UCSF GRCh37 12 125509705 125509705 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 47 52 0 ENST00000341446.8:c.485G>A p.Arg162Gln p.R162Q ENST00000341446 NM_080626.5 162 cGg/cAg 0 +BRPF1 UCSF GRCh37 3 9785495 9785495 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 20 28 0 ENST00000457855.1:c.2527G>A p.Gly843Ser p.G843S ENST00000457855 843 Ggt/Agt 0 +BRWD1 UCSF GRCh37 21 40601293 40601293 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 32 41 0 ENST00000333229.2:c.3070C>T p.Leu1024= p.L1024= ENST00000333229 NM_018963.4 1024 Cta/Tta 0 +BRWD1 UCSF GRCh37 21 40590459 40590459 + synonymous_variant Silent SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 32 46 0 ENST00000333229.2:c.3510C>A p.Ile1170= p.I1170= ENST00000333229 NM_018963.4 1170 atC/atA 0 +BRWD3 UCSF GRCh37 X 79989714 79989714 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 32 79 0 ENST00000373275.4:c.989G>A p.Gly330Asp p.G330D ENST00000373275 NM_153252.4 330 gGt/gAt 0 +BSN UCSF GRCh37 3 49689037 49689037 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 58 42 0 ENST00000296452.4:c.2048C>T p.Thr683Ile p.T683I ENST00000296452 NM_003458.3 683 aCa/aTa 0 +BSN UCSF GRCh37 3 49680541 49680541 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 20 26 0 ENST00000296452.4:c.1474G>A p.Val492Met p.V492M ENST00000296452 NM_003458.3 492 Gtg/Atg 0 +BSN UCSF GRCh37 3 49689614 49689614 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 19 25 0 ENST00000296452.4:c.2625G>A p.Gln875= p.Q875= ENST00000296452 NM_003458.3 875 caG/caA 0 +BTBD7 UCSF GRCh37 14 93712565 93712565 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 17 61 0 ENST00000334746.5:c.2189C>T p.Pro730Leu p.P730L ENST00000334746 NM_001002860.2 730 cCt/cTt 0 +BTG2 UCSF GRCh37 1 203276539 203276539 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 32 26 0 ENST00000290551.4:c.450G>A p.Lys150= p.K150= ENST00000290551 NM_006763.2 150 aaG/aaA 0 +C10orf10 UCSF GRCh37 10 45473337 45473337 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 55 39 0 ENST00000298295.3:c.142G>A p.Ala48Thr p.A48T ENST00000298295 NM_007021.3 48 Gca/Aca 0 +C10orf12 UCSF GRCh37 10 98744807 98744807 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 37 72 0 ENST00000286067.2:c.3660G>A p.Glu1220= p.E1220= ENST00000286067 NM_015652.2 1220 gaG/gaA 0 +C10orf120 UCSF GRCh37 10 124459240 124459240 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 33 61 0 ENST00000329446.4:c.67C>T p.Gln23Ter p.Q23* ENST00000329446 NM_001010912.2 23 Caa/Taa 0 +C10orf68 UCSF GRCh37 10 32983896 32983896 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 16 24 0 ENST00000375025.4:c.355C>T p.Leu119Phe p.L119F ENST00000375025 119 Ctt/Ttt 0 +C11orf66 UCSF GRCh37 11 61249350 61249350 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 34 17 0 ENST00000338608.2:c.69C>T p.Asp23= p.D23= ENST00000338608 NM_145017.2 23 gaC/gaT 0 +C12orf11 UCSF GRCh37 12 27077313 27077313 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 26 54 0 ENST00000261191.7:c.779C>T p.Thr260Ile p.T260I ENST00000261191 NM_018164.2 260 aCt/aTt 0 +C12orf11 UCSF GRCh37 12 27066981 27066981 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 33 29 0 ENST00000261191.7:c.1500C>T p.Asn500= p.N500= ENST00000261191 NM_018164.2 500 aaC/aaT 0 +C12orf51 UCSF GRCh37 12 112613626 112613626 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 160 33 126 1 ENST00000550722.1:c.11070C>T p.His3690= p.H3690= ENST00000550722 NM_001109662.3 3690 caC/caT 0 +C13orf27 UCSF GRCh37 13 103420646 103420646 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 25 56 56 0 ENST00000376032.4:c.262T>C p.Ser88Pro p.S88P ENST00000376032 NM_138779.3 88 Tca/Cca 0 +C14orf102 UCSF GRCh37 14 90770410 90770410 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 115 71 117 0 ENST00000354366.3:c.874G>A p.Glu292Lys p.E292K ENST00000354366 NM_017970.3 292 Gaa/Aaa 0 +C14orf28 UCSF GRCh37 14 45369727 45369727 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 36 74 0 ENST00000325192.3:c.89G>A p.Gly30Glu p.G30E ENST00000325192 NM_001017923.1 30 gGg/gAg 0 +C15orf27 UCSF GRCh37 15 76496215 76496215 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 56 57 0 ENST00000388942.3:c.1155C>T p.Thr385= p.T385= ENST00000388942 NM_152335.2 385 acC/acT 0 +C15orf33 UCSF GRCh37 15 49663565 49663565 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 122 63 102 0 ENST00000299338.6:c.1044C>T p.Asn348= p.N348= ENST00000299338 NM_152647.2 348 aaC/aaT 0 +C15orf55 UCSF GRCh37 15 34640819 34640819 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 47 77 0 ENST00000333756.4:c.666C>T p.Ala222= p.A222= ENST00000333756 NM_175741.1 222 gcC/gcT 0 +C16orf57 UCSF GRCh37 16 58043838 58043838 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 50 69 0 ENST00000219281.3:c.271G>A p.Ala91Thr p.A91T ENST00000219281 NM_024598.3 91 Gcc/Acc 0 +C16orf58 UCSF GRCh37 16 31510822 31510822 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 17 8 21 0 ENST00000327237.2:c.486G>A p.Lys162= p.K162= ENST00000327237 NM_022744.3 162 aaG/aaA 0 +C16orf71 UCSF GRCh37 16 4790360 4790360 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 47 28 0 ENST00000299320.5:c.483C>T p.Ser161= p.S161= ENST00000299320 NM_139170.2 161 tcC/tcT 0 +C17orf104 UCSF GRCh37 17 42745345 42745345 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 62 87 0 ENST00000409122.2:c.2066C>T p.Pro689Leu p.P689L ENST00000409122 NM_001145080.2 689 cCc/cTc 0 +C17orf74 UCSF GRCh37 17 7330099 7330099 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 45 35 0 ENST00000333870.3:c.789C>T p.Ser263= p.S263= ENST00000333870 NM_175734.4 263 tcC/tcT 0 +C17orf78 UCSF GRCh37 17 35745639 35745639 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 49 91 0 ENST00000300618.4:c.543G>A p.Trp181Ter p.W181* ENST00000300618 NM_173625.3 181 tgG/tgA 0 +C17orf80 UCSF GRCh37 17 71231716 71231716 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 26 58 0 ENST00000359042.2:c.95G>A p.Gly32Glu p.G32E ENST00000359042 NM_017941.4 32 gGa/gAa 0 +C17orf85 UCSF GRCh37 17 3721832 3721832 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 58 105 0 ENST00000389005.4:c.1035G>A p.Glu345= p.E345= ENST00000389005 NM_001114118.2 345 gaG/gaA 0 +C1orf116 UCSF GRCh37 1 207195526 207195526 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 22 30 0 ENST00000359470.5:c.1583C>T p.Pro528Leu p.P528L ENST00000359470 NM_023938.5 528 cCc/cTc 0 +C1orf55 UCSF GRCh37 1 226179064 226179064 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 25 60 0 ENST00000272091.7:c.521G>A p.Gly174Asp p.G174D ENST00000272091 NM_152608.3 174 gGt/gAt 0 +C20orf194 UCSF GRCh37 20 3275275 3275275 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 20 35 0 ENST00000252032.9:c.2019G>A p.Leu673= p.L673= ENST00000252032 NM_001009984.2 673 ttG/ttA 0 +C20orf20 UCSF GRCh37 20 61429976 61429976 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 225 154 137 0 ENST00000370487.3:c.308G>A p.Arg103Lys p.R103K ENST00000370487 NM_018270.4 103 aGg/aAg 0 +C20orf43 UCSF GRCh37 20 55092182 55092182 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 20 44 0 ENST00000357348.5:c.757G>A p.Val253Ile p.V253I ENST00000357348 NM_001283035.1 253 Gtt/Att 0 +C21orf63 UCSF GRCh37 21 33887344 33887344 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 42 84 0 ENST00000300255.2:c.1170G>A p.Leu390= p.L390= ENST00000300255 NM_058187.3 390 ctG/ctA 0 +C2orf67 UCSF GRCh37 2 210889860 210889860 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 42 44 0 ENST00000281772.9:c.2532G>A p.Trp844Ter p.W844* ENST00000281772 NM_152519.2 844 tgG/tgA 0 +C3orf20 UCSF GRCh37 3 14799102 14799102 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 27 13 0 ENST00000253697.3:c.2165C>T p.Thr722Ile p.T722I ENST00000253697 NM_032137.4 722 aCc/aTc 0 +C3orf35 UCSF GRCh37 3 37459110 37459110 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 189 39 97 0 ENST00000328376.5:c.226+127G>A *76* ENST00000328376 NM_178339.2 0 +C4A UCSF GRCh37 6 31997482 31997482 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 132 31 97 0 ENST00000435363.2:c.3816C>T p.Leu1272= p.L1272= ENST00000435363 NM_001002029.3 1272 ctC/ctT 0 +C4orf40 UCSF GRCh37 4 71024297 71024297 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 129 88 122 0 ENST00000344526.5:c.328C>T p.Pro110Ser p.P110S ENST00000344526 NM_214711.3 110 Ccg/Tcg 0 +C5orf38 UCSF GRCh37 5 2752772 2752772 + upstream_gene_variant 5'Flank SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 116 76 67 0 ENST00000302057 NM_033267.4 0 +C5orf42 UCSF GRCh37 5 37245866 37245866 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 38 37 0 ENST00000425232.2:c.163C>T p.Pro55Ser p.P55S ENST00000425232 NM_023073.3 55 Cct/Tct 0 +C5orf51 UCSF GRCh37 5 41917238 41917238 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 35 77 0 ENST00000381647.2:c.722G>A p.Gly241Glu p.G241E ENST00000381647 NM_175921.4 241 gGa/gAa 0 +C6orf103 UCSF GRCh37 6 147073673 147073673 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 27 69 0 ENST00000397944.3:c.3373G>A p.Val1125Ile p.V1125I ENST00000397944 NM_024694.3 1125 Gtt/Att 0 +C6orf106 UCSF GRCh37 6 34614419 34614419 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 52 97 0 ENST00000374023.3:c.470G>A p.Gly157Glu p.G157E ENST00000374023 NM_024294.2 157 gGa/gAa 0 +C6orf118 UCSF GRCh37 6 165703467 165703467 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 47 64 0 ENST00000230301.8:c.1210G>A p.Asp404Asn p.D404N ENST00000230301 NM_144980.3 404 Gat/Aat 0 +C6orf168 UCSF GRCh37 6 99771450 99771450 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 51 16 38 0 ENST00000389677.5:c.693G>A p.Arg231= p.R231= ENST00000389677 NM_032511.2 231 agG/agA 0 +C6orf27 UCSF GRCh37 6 31735267 31735267 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 65 111 0 ENST00000375688.4:c.1661G>A p.Gly554Asp p.G554D ENST00000375688 554 gGc/gAc 0 +C6orf48 UCSF GRCh37 6 31807392 31807392 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 36 85 0 ENST00000375633.1:c.180C>T p.Ser60= p.S60= ENST00000375633 NM_001287488.1 60 tcC/tcT 0 +C6orf97 UCSF GRCh37 6 151894324 151894324 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 28 69 0 ENST00000239374.7:c.790G>A p.Val264Ile p.V264I ENST00000239374 NM_025059.3 264 Gta/Ata 0 +C6orf97 UCSF GRCh37 6 151894326 151894326 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 74 28 72 0 ENST00000239374.7:c.792A>G p.Val264= p.V264= ENST00000239374 NM_025059.3 264 gtA/gtG 0 +C7orf30 UCSF GRCh37 7 23339170 23339170 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 3 12 0 ENST00000466681.1:c.199C>T p.Leu67= p.L67= ENST00000466681 NM_138446.1 67 Ctg/Ttg 0 +C7orf51 UCSF GRCh37 7 100085797 100085797 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 271 99 133 0 ENST00000300179.2:c.453G>A p.Glu151= p.E151= ENST00000300179 NM_173564.3 151 gaG/gaA 0 +C7orf58 UCSF GRCh37 7 120629737 120629737 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 144 66 0 ENST00000310396.5:c.62G>A p.Gly21Asp p.G21D ENST00000310396 NM_024913.4 21 gGc/gAc 0 +C7orf64 UCSF GRCh37 7 92158212 92158212 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 12 19 0 ENST00000265732.5:c.85G>A p.Glu29Lys p.E29K ENST00000265732 NM_032120.2 29 Gag/Aag 0 +C8A UCSF GRCh37 1 57373672 57373672 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 25 53 0 ENST00000361249.3:c.1266G>A p.Arg422= p.R422= ENST00000361249 NM_000562.2 422 cgG/cgA 0 +C8orf33 UCSF GRCh37 8 146278156 146278156 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 108 48 29 0 ENST00000331434.6:c.191G>A p.Gly64Asp p.G64D ENST00000331434 NM_023080.2 64 gGc/gAc 0 +C8orf34 UCSF GRCh37 8 69381015 69381015 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 32 81 0 ENST00000518698.1:c.696G>A p.Glu232= p.E232= ENST00000518698 NM_052958.2 232 gaG/gaA 0 +C8orf76 UCSF GRCh37 8 124243833 124243833 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 145 96 139 0 ENST00000276704.4:c.522C>T p.Tyr174= p.Y174= ENST00000276704 NM_032847.2 174 taC/taT 0 +C8orf80 UCSF GRCh37 8 27922104 27922104 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 119 79 128 0 ENST00000413272.2:c.856G>A p.Val286Ile p.V286I ENST00000413272 NM_001010906.1 286 Gtc/Atc 0 +C9orf117 UCSF GRCh37 9 130474170 130474170 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 13 9 0 ENST00000373295.2:c.927C>T p.Leu309= p.L309= ENST00000373295 NM_001012502.2 309 ctC/ctT 0 +C9orf152 UCSF GRCh37 9 112963293 112963293 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 35 81 0 ENST00000400613.4:c.655C>T p.Pro219Ser p.P219S ENST00000400613 NM_001012993.2 219 Ccc/Tcc 0 +C9orf152 UCSF GRCh37 9 112963491 112963491 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 52 136 0 ENST00000400613.4:c.457C>T p.Pro153Ser p.P153S ENST00000400613 NM_001012993.2 153 Cct/Tct 0 +C9orf50 UCSF GRCh37 9 132381915 132381915 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 198 74 57 0 ENST00000372478.4:c.600G>A p.Trp200Ter p.W200* ENST00000372478 NM_199350.3 200 tgG/tgA 0 +C9orf84 UCSF GRCh37 9 114454608 114454608 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 64 105 0 ENST00000318737.4:c.3457G>A p.Glu1153Lys p.E1153K ENST00000318737 NM_173521.3 1153 Gag/Aag 0 +C9orf84 UCSF GRCh37 9 114543245 114543245 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 15 46 0 ENST00000318737.4:c.30G>A p.Trp10Ter p.W10* ENST00000318737 NM_173521.3 10 tgG/tgA 0 +CA12 UCSF GRCh37 15 63618500 63618500 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 40 43 0 ENST00000178638.3:c.1049C>T p.Thr350Ile p.T350I ENST00000178638 NM_001218.3 350 aCt/aTt 0 +CABS1 UCSF GRCh37 4 71201897 71201897 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 55 37 69 0 ENST00000273936.5:c.1141G>A p.Asp381Asn p.D381N ENST00000273936 NM_033122.3 381 Gat/Aat 0 +CACNA1S UCSF GRCh37 1 201009472 201009472 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 22 20 0 ENST00000362061.3:c.5257G>A p.Asp1753Asn p.D1753N ENST00000362061 NM_000069.2 1753 Gac/Aac 0 +CACNA2D3 UCSF GRCh37 3 54661876 54661876 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 52 111 0 ENST00000288197.5:c.1026G>A p.Leu342= p.L342= ENST00000288197 342 ctG/ctA 0 +CADPS UCSF GRCh37 3 62648069 62648069 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 31 41 0 ENST00000383710.4:c.889C>T p.Leu297= p.L297= ENST00000383710 NM_003716.3 297 Ctg/Ttg 0 +CALB2 UCSF GRCh37 16 71416647 71416647 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 29 84 0 ENST00000302628.4:c.368G>A p.Arg123Lys p.R123K ENST00000302628 NM_001740.4 123 aGg/aAg 0 +CAMK1G UCSF GRCh37 1 209776620 209776620 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 21 43 0 ENST00000009105.1:c.283C>T p.Leu95= p.L95= ENST00000009105 95 Ctg/Ttg 0 +CAMSAP1 UCSF GRCh37 9 138773575 138773575 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 71 63 0 ENST00000389532.4:c.489G>A p.Glu163= p.E163= ENST00000389532 NM_015447.3 163 gaG/gaA 0 +CAMTA1 UCSF GRCh37 1 7737659 7737659 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 64 79 0 ENST00000303635.7:c.2780C>T p.Ala927Val p.A927V ENST00000303635 NM_015215.2 927 gCc/gTc 0 +CAPN1 UCSF GRCh37 11 64956121 64956121 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 35 35 0 ENST00000279247.6:c.1069G>A p.Ala357Thr p.A357T ENST00000279247 NM_005186.3 357 Gcc/Acc 0 +CAPN12 UCSF GRCh37 19 39224996 39224996 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 17 26 0 ENST00000328867.4:c.1778G>A p.Gly593Glu p.G593E ENST00000328867 NM_144691.3 593 gGg/gAg 0 +CAPN3 UCSF GRCh37 15 42703102 42703102 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 39 42 0 ENST00000397163.3:c.2284C>T p.Leu762Phe p.L762F ENST00000397163 NM_000070.2 762 Ctc/Ttc 0 +CAPS UCSF GRCh37 19 5914424 5914424 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 40 45 0 ENST00000222125.5:c.7G>A p.Ala3Thr p.A3T ENST00000222125 NM_004058.3 3 Gcc/Acc 0 +CAPZA2 UCSF GRCh37 7 116544243 116544243 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 166 34 74 0 ENST00000361183.3:c.232G>A p.Glu78Lys p.E78K ENST00000361183 NM_006136.2 78 Gaa/Aaa 0 +CARS UCSF GRCh37 11 3028128 3028128 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 98 97 0 ENST00000397111.5:c.1881G>A p.Val627= p.V627= ENST00000397111 627 gtG/gtA 0 +CASP10 UCSF GRCh37 2 202060618 202060618 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 110 47 153 0 ENST00000272879.5:c.631G>A p.Glu211Lys p.E211K ENST00000272879 NM_032974.4 211 Gag/Aag 0 +CBL UCSF GRCh37 11 119169134 119169134 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 39 54 0 ENST00000264033.4:c.2318G>A p.Gly773Glu p.G773E ENST00000264033 NM_005188.3 773 gGg/gAg 0 +CBLB UCSF GRCh37 3 105400646 105400646 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 22 44 0 ENST00000264122.4:c.2218C>T p.His740Tyr p.H740Y ENST00000264122 NM_170662.3 740 Cac/Tac 0 +CBX1 UCSF GRCh37 17 46153525 46153525 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 23 55 0 ENST00000225603.4:c.156G>A p.Trp52Ter p.W52* ENST00000225603 NM_001127228.1 52 tgG/tgA 0 +CC2D2A UCSF GRCh37 4 15569352 15569352 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 67 111 0 ENST00000424120.1:c.3341C>T p.Thr1114Met p.T1114M ENST00000424120 1114 aCg/aTg 0 +CC2D2A UCSF GRCh37 4 15538543 15538543 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 46 80 0 ENST00000424120.1:c.1608G>A p.Lys536= p.K536= ENST00000424120 536 aaG/aaA 0 +CCBE1 UCSF GRCh37 18 57105359 57105359 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 11 27 0 ENST00000439986.4:c.971G>A p.Gly324Glu p.G324E ENST00000439986 NM_133459.3 324 gGg/gAg 0 +CCDC102A UCSF GRCh37 16 57546657 57546657 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 45 29 0 ENST00000258214.2:c.1649C>T p.Ala550Val p.A550V ENST00000258214 NM_033212.3 550 gCc/gTc 0 +CCDC107 UCSF GRCh37 9 35660428 35660428 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 58 55 0 ENST00000426546.2:c.289G>A p.Glu97Lys p.E97K ENST00000426546 NM_001195201.1 97 Gag/Aag 0 +CCDC114 UCSF GRCh37 19 48806279 48806279 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 36 32 0 ENST00000315396.7:c.951G>A p.Glu317= p.E317= ENST00000315396 NM_144577.3 317 gaG/gaA 0 +CCDC134 UCSF GRCh37 22 42209290 42209290 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 38 59 0 ENST00000255784.5:c.333C>T p.Asn111= p.N111= ENST00000255784 NM_024821.2 111 aaC/aaT 0 +CCDC138 UCSF GRCh37 2 109410995 109410995 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 24 67 0 ENST00000295124.4:c.395-1G>A p.X132_splice ENST00000295124 NM_144978.1 0 +CCDC14 UCSF GRCh37 3 123680084 123680084 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 6 20 0 ENST00000433542.2:c.81G>A p.Ala27= p.A27= ENST00000433542 NM_022757.4 27 gcG/gcA 0 +CCDC146 UCSF GRCh37 7 76888377 76888377 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 15 15 0 ENST00000285871.4:c.750C>T p.Arg250= p.R250= ENST00000285871 NM_020879.2 250 cgC/cgT 0 +CCDC146 UCSF GRCh37 7 76924039 76924039 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 39 66 0 ENST00000285871.4:c.2724G>A p.Gln908= p.Q908= ENST00000285871 NM_020879.2 908 caG/caA 0 +CCDC149 UCSF GRCh37 4 24810101 24810101 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 38 34 0 ENST00000504487.1:c.1500G>A p.Glu500= p.E500= ENST00000504487 NM_001130726.2 500 gaG/gaA 0 +CCDC150 UCSF GRCh37 2 197595664 197595664 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 25 74 0 ENST00000389175.4:c.3064G>A p.Glu1022Lys p.E1022K ENST00000389175 NM_001080539.1 1022 Gaa/Aaa 0 +CCDC57 UCSF GRCh37 17 80156261 80156261 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 53 29 41 0 ENST00000389641.4:c.445T>C p.Tyr149His p.Y149H ENST00000389641 149 Tat/Cat 0 +CCDC57 UCSF GRCh37 17 80146139 80146139 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 32 20 0 ENST00000389641.4:c.1008G>A p.Trp336Ter p.W336* ENST00000389641 336 tgG/tgA 0 +CCDC57 UCSF GRCh37 17 80086473 80086473 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 24 17 0 ENST00000389641.4:c.2245G>A p.Asp749Asn p.D749N ENST00000389641 749 Gac/Aac 0 +CCDC60 UCSF GRCh37 12 119954456 119954456 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 11 46 0 ENST00000327554.2:c.912G>A p.Arg304= p.R304= ENST00000327554 NM_178499.3 304 cgG/cgA 0 +CCDC65 UCSF GRCh37 12 49310856 49310856 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 26 49 0 ENST00000320516.4:c.574G>A p.Glu192Lys p.E192K ENST00000320516 NM_033124.4 192 Gag/Aag 0 +CCDC66 UCSF GRCh37 3 56592873 56592873 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 22 23 0 ENST00000394672.3:c.12-1G>A p.X4_splice ENST00000394672 NM_001141947.1 0 +CCDC66 UCSF GRCh37 3 56651234 56651234 + synonymous_variant Silent SNP G G A snp132_rs114565523 P05_Rec Untested WXS Illumina HiSeq 62 19 50 0 ENST00000394672.3:c.1938G>A p.Ser646= p.S646= ENST00000394672 NM_001141947.1 646 tcG/tcA 0 +CCDC8 UCSF GRCh37 19 46914669 46914669 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 42 48 0 ENST00000307522.3:c.1399C>T p.Pro467Ser p.P467S ENST00000307522 NM_032040.4 467 Cca/Tca 0 +CCDC88A UCSF GRCh37 2 55522966 55522966 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 47 73 0 ENST00000436346.1:c.5318C>T p.Pro1773Leu p.P1773L ENST00000436346 NM_001135597.1 1773 cCt/cTt 0 +CCDC88B UCSF GRCh37 11 64112135 64112135 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 16 11 0 ENST00000356786.5:c.2122G>A p.Val708Ile p.V708I ENST00000356786 NM_032251.5 708 Gtc/Atc 0 +CCNG2 UCSF GRCh37 4 78080624 78080624 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 58 59 0 ENST00000316355.5:c.243C>T p.Val81= p.V81= ENST00000316355 NM_004354.2 81 gtC/gtT 0 +CCNJL UCSF GRCh37 5 159680671 159680671 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 32 30 0 ENST00000393977.3:c.1022C>T p.Thr341Ile p.T341I ENST00000393977 NM_024565.5 341 aCc/aTc 0 +CCNT1 UCSF GRCh37 12 49087669 49087669 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 44 88 0 ENST00000261900.3:c.1328G>A p.Gly443Asp p.G443D ENST00000261900 NM_001240.3 443 gGt/gAt 0 +CCP110 UCSF GRCh37 16 19547481 19547481 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 48 81 0 ENST00000381396.5:c.490G>A p.Asp164Asn p.D164N ENST00000381396 NM_001199022.1 164 Gat/Aat 0 +CD109 UCSF GRCh37 6 74528156 74528156 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 28 39 0 ENST00000287097.5:c.3957C>T p.Asn1319= p.N1319= ENST00000287097 1319 aaC/aaT 0 +CD163 UCSF GRCh37 12 7647854 7647854 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 61 88 0 ENST00000359156.4:c.1243G>A p.Gly415Arg p.G415R ENST00000359156 NM_004244.5 415 Gga/Aga 0 +CD19 UCSF GRCh37 16 28943335 28943335 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 41 53 0 ENST00000324662.3:c.14G>A p.Arg5His p.R5H ENST00000324662 5 cGc/cAc 0 +CD244 UCSF GRCh37 1 160802358 160802358 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 28 73 0 ENST00000368033.3:c.983C>T p.Ser328Phe p.S328F ENST00000368033 328 tCc/tTc 0 +CD244 UCSF GRCh37 1 160811234 160811234 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 40 77 0 ENST00000368033.3:c.436C>T p.Leu146= p.L146= ENST00000368033 146 Ctg/Ttg 0 +CD248 UCSF GRCh37 11 66083250 66083250 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 104 49 56 0 ENST00000311330.3:c.1249G>A p.Asp417Asn p.D417N ENST00000311330 NM_020404.2 417 Gac/Aac 0 +CD300LG UCSF GRCh37 17 41926176 41926176 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 34 65 0 ENST00000317310.4:c.294C>T p.Thr98= p.T98= ENST00000317310 NM_145273.3 98 acC/acT 0 +CD33 UCSF GRCh37 19 51728619 51728619 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 52 102 0 ENST00000262262.4:c.183C>T p.Phe61= p.F61= ENST00000262262 NM_001772.3 61 ttC/ttT 0 +CDC16 UCSF GRCh37 13 115037701 115037701 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 28 40 72 0 ENST00000356221.3:c.1646T>C p.Val549Ala p.V549A ENST00000356221 549 gTg/gCg 0 +CDC27 UCSF GRCh37 17 45232117 45232117 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 48 65 0 ENST00000066544.3:c.878G>A p.Gly293Glu p.G293E ENST00000066544 NM_001256.3 293 gGa/gAa 0 +CDC42BPA UCSF GRCh37 1 227204712 227204712 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 45 88 0 ENST00000334218.5:c.4550G>A p.Ser1517Asn p.S1517N ENST00000334218 1517 aGt/aAt 0 +CDC42BPG UCSF GRCh37 11 64607621 64607621 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 26 23 0 ENST00000342711.5:c.552C>T p.His184= p.H184= ENST00000342711 NM_017525.2 184 caC/caT 0 +CDC42BPG UCSF GRCh37 11 64596944 64596944 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 22 14 0 ENST00000342711.5:c.3966G>A p.Trp1322Ter p.W1322* ENST00000342711 NM_017525.2 1322 tgG/tgA 0 +CDCA7 UCSF GRCh37 2 174229627 174229627 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0030 P05_Rec Untested WXS Illumina HiSeq 46 51 57 0 ENST00000347703.3:c.567G>A p.Gly189= p.G189= ENST00000347703 NM_145810.2 189 ggG/ggA 0 +CDCP2 UCSF GRCh37 1 54610301 54610301 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 25 32 0 ENST00000371330.1:c.265G>A p.Glu89Lys p.E89K ENST00000371330 NM_201546.3 89 Gag/Aag 0 +CDH1 UCSF GRCh37 16 68867309 68867309 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 30 70 0 ENST00000261769.5:c.2556G>A p.Glu852= p.E852= ENST00000261769 NM_004360.3 852 gaG/gaA 0 +CDH19 UCSF GRCh37 18 64235770 64235770 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 49 97 0 ENST00000262150.2:c.373G>A p.Gly125Arg p.G125R ENST00000262150 NM_021153.3 125 Gga/Aga 0 +CDH23 UCSF GRCh37 10 73434906 73434906 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.252,1000g2011may_all_0.28177,snp132_rs10999947 P05_Rec Untested WXS Illumina HiSeq 20 31 54 0 ENST00000224721.6:c.1502G>A p.Ser501Asn p.S501N ENST00000224721 NM_022124.5 501 aGc/aAc 0 +CDH24 UCSF GRCh37 14 23523978 23523978 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 43 47 0 ENST00000267383.5:c.594C>T p.Phe198= p.F198= ENST00000267383 198 ttC/ttT 0 +CDH8 UCSF GRCh37 16 61858915 61858915 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 53 82 0 ENST00000577390.1:c.835+1G>A p.X279_splice ENST00000577390 NM_001796.4 0 +CDH9 UCSF GRCh37 5 26886136 26886136 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 48 88 0 ENST00000231021.4:c.1569C>T p.Phe523= p.F523= ENST00000231021 NM_016279.3 523 ttC/ttT 0 +CDHR3 UCSF GRCh37 7 105624728 105624728 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 25 48 0 ENST00000317716.9:c.506C>T p.Pro169Leu p.P169L ENST00000317716 NM_152750.4 169 cCc/cTc 0 +CDK10 UCSF GRCh37 16 89755684 89755684 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 10 29 0 ENST00000353379.7:c.112G>A p.Glu38Lys p.E38K ENST00000353379 NM_052988.4 38 Gag/Aag 0 +CDK11A UCSF GRCh37 1 1634940 1634940 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 10 26 0 ENST00000378633.1:c.2044G>A p.Asp682Asn p.D682N ENST00000378633 682 Gac/Aac 0 +CDK11B UCSF GRCh37 1 1571841 1571841 + missense_variant,splice_region_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 75 11 40 0 ENST00000407249.3:c.1929T>G p.Asp643Glu p.D643E ENST00000407249 643 gaT/gaG 0 +CDK12 UCSF GRCh37 17 37667883 37667883 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 25 61 1 ENST00000447079.4:c.2768G>A p.Gly923Glu p.G923E ENST00000447079 NM_015083.1 923 gGa/gAa 0 +CDK13 UCSF GRCh37 7 40132563 40132563 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 176 70 161 0 ENST00000181839.4:c.3415G>A p.Gly1139Ser p.G1139S ENST00000181839 NM_031267.3 1139 Ggt/Agt 0 +CDK18 UCSF GRCh37 1 205495550 205495550 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 47 71 0 ENST00000506784.1:c.717C>T p.Ile239= p.I239= ENST00000506784 239 atC/atT 0 +CDK20 UCSF GRCh37 9 90585714 90585714 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 16 16 0 ENST00000325303.8:c.477C>T p.Leu159= p.L159= ENST00000325303 NM_001039803.2 159 ctC/ctT 0 +CDK4 UCSF GRCh37 12 58145092 58145092 + synonymous_variant Silent SNP G G A NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 118 44 87 0 ENST00000257904.6:c.252C>T p.Asp84= p.D84= ENST00000257904 NM_000075.3 84 gaC/gaT 0 +CDK6 UCSF GRCh37 7 92244504 92244504 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 35 10 36 0 ENST00000265734.4:c.931G>A p.Asp311Asn p.D311N ENST00000265734 NM_001259.6 311 Gat/Aat 0 +CDKN2A UCSF GRCh37 9 21971017 21971017 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 25 34 23 0 ENST00000304494.5:c.341C>T p.Pro114Leu p.P114L ENST00000304494 NM_000077.4 114 cCc/cTc 0 +CDYL2 UCSF GRCh37 16 80654695 80654695 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 18 42 0 ENST00000570137.2:c.972G>A p.Arg324= p.R324= ENST00000570137 NM_152342.2 324 cgG/cgA 0 +CEACAM16 UCSF GRCh37 19 45208927 45208927 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 46 71 0 ENST00000405314.2:c.729C>T p.Asp243= p.D243= ENST00000405314 243 gaC/gaT 0 +CEACAM5 UCSF GRCh37 19 42224071 42224071 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 121 81 185 0 ENST00000221992.6:c.1715G>A p.Gly572Glu p.G572E ENST00000221992 NM_004363.2 572 gGa/gAa 0 +CECR2 UCSF GRCh37 22 18018789 18018789 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 133 106 179 0 ENST00000342247.5:c.1326G>A p.Lys442= p.K442= ENST00000342247 442 aaG/aaA 0 +CELF2 UCSF GRCh37 10 11367840 11367840 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 43 70 0 ENST00000416382.2:c.1297G>A p.Glu433Lys p.E433K ENST00000416382 433 Gaa/Aaa 0 +CELF4 UCSF GRCh37 18 34850748 34850748 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 22 40 0 ENST00000420428.2:c.1082G>A p.Gly361Asp p.G361D ENST00000420428 NM_020180.3 361 gGc/gAc 0 +CELSR1 UCSF GRCh37 22 46794525 46794525 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 26 30 0 ENST00000262738.3:c.5422G>A p.Asp1808Asn p.D1808N ENST00000262738 NM_014246.1 1808 Gat/Aat 0 +CELSR3 UCSF GRCh37 3 48677633 48677633 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 40 28 0 ENST00000164024.4:c.9385G>A p.Asp3129Asn p.D3129N ENST00000164024 NM_001407.2 3129 Gac/Aac 0 +CENPE UCSF GRCh37 4 104102587 104102587 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 28 33 0 ENST00000265148.3:c.990G>A p.Lys330= p.K330= ENST00000265148 NM_001813.2 330 aaG/aaA 0 +CENPJ UCSF GRCh37 13 25458563 25458563 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 24 52 0 ENST00000381884.4:c.3516G>A p.Leu1172= p.L1172= ENST00000381884 NM_018451.4 1172 ctG/ctA 0 +CENPT UCSF GRCh37 16 67865247 67865247 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 32 52 0 ENST00000440851.2:c.575C>T p.Thr192Ile p.T192I ENST00000440851 192 aCc/aTc 0 +CEP104 UCSF GRCh37 1 3768942 3768942 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 27 36 0 ENST00000378230.3:c.30C>T p.Val10= p.V10= ENST00000378230 NM_014704.3 10 gtC/gtT 0 +CEP128 UCSF GRCh37 14 80993238 80993238 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 22 52 0 ENST00000281129.3:c.3047C>T p.Thr1016Ile p.T1016I ENST00000281129 NM_152446.3 1016 aCc/aTc 0 +CEP250 UCSF GRCh37 20 34057745 34057745 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 61 62 0 ENST00000397527.1:c.882G>A p.Gln294= p.Q294= ENST00000397527 NM_007186.3 294 caG/caA 0 +CEP290 UCSF GRCh37 12 88505548 88505548 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 25 23 0 ENST00000552810.1:c.2140G>A p.Glu714Lys p.E714K ENST00000552810 NM_025114.3 714 Gaa/Aaa 0 +CHAC1 UCSF GRCh37 15 41247886 41247886 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 65 35 0 ENST00000446533.3:c.709G>A p.Asp237Asn p.D237N ENST00000446533 NM_024111.3 237 Gac/Aac 0 +CHD1L UCSF GRCh37 1 146740464 146740464 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 22 31 0 ENST00000369258.4:c.1012G>A p.Val338Ile p.V338I ENST00000369258 NM_001256336.1 338 Gtt/Att 0 +CHD5 UCSF GRCh37 1 6211163 6211163 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 25 60 0 ENST00000262450.3:c.923G>A p.Ser308Asn p.S308N ENST00000262450 NM_015557.2 308 aGt/aAt 0 +CHD8 UCSF GRCh37 14 21870663 21870663 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 26 114 0 ENST00000399982.2:c.3715-1G>A p.X1239_splice ENST00000399982 NM_001170629.1 0 +CHI3L2 UCSF GRCh37 1 111781386 111781386 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 32 82 0 ENST00000369748.4:c.750G>A p.Gly250= p.G250= ENST00000369748 NM_004000.2 250 ggG/ggA 0 +CHRD UCSF GRCh37 3 184107167 184107167 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 8 8 23 0 ENST00000204604.1:c.2825C>T p.Thr942Ile p.T942I ENST00000204604 NM_003741.2 942 aCc/aTc 0 +CHRM1 UCSF GRCh37 11 62677223 62677223 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 85 30 0 ENST00000306960.3:c.1350C>T p.Gly450= p.G450= ENST00000306960 NM_000738.2 450 ggC/ggT 0 +CHRM3 UCSF GRCh37 1 240071285 240071285 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 63 110 0 ENST00000255380.4:c.534C>T p.Ala178= p.A178= ENST00000255380 NM_000740.2 178 gcC/gcT 0 +CHRM5 UCSF GRCh37 15 34355661 34355661 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 84 94 0 ENST00000383263.5:c.743C>T p.Ala248Val p.A248V ENST00000383263 NM_012125.3 248 gCt/gTt 0 +CHRNA2 UCSF GRCh37 8 27320517 27320517 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 153 88 63 0 ENST00000407991.1:c.1443G>A p.Arg481= p.R481= ENST00000407991 NM_000742.3 481 cgG/cgA 0 +CHRNE UCSF GRCh37 17 4802823 4802823 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 17 10 0 ENST00000293780.4:c.972C>T p.Ile324= p.I324= ENST00000293780 NM_000080.3 324 atC/atT 0 +CHTOP UCSF GRCh37 1 153610925 153610925 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 28 75 0 ENST00000368694.3:c.219+1G>A p.X73_splice ENST00000368694 NM_001206612.1 0 +CHURC1-FNTB UCSF GRCh37 14 65507588 65507588 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 32 81 0 ENST00000246166.2:c.773C>T p.Ala258Val p.A258V ENST00000246166 NM_002028.3 258 gCg/gTg 0 +CIDEC UCSF GRCh37 3 9911904 9911904 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 23 51 0 ENST00000336832.2:c.310G>A p.Asp104Asn p.D104N ENST00000336832 NM_022094.3 104 Gat/Aat 0 +CIDEC UCSF GRCh37 3 9911985 9911985 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 33 68 1 ENST00000336832.2:c.229G>A p.Ala77Thr p.A77T ENST00000336832 NM_022094.3 77 Gca/Aca 0 +CIT UCSF GRCh37 12 120148087 120148087 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 68 62 99 0 ENST00000261833.7:c.4914C>G p.Ile1638Met p.I1638M ENST00000261833 NM_007174.2 1638 atC/atG 0 +CIT UCSF GRCh37 12 120198744 120198744 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 158 37 133 0 ENST00000261833.7:c.2294C>T p.Ala765Val p.A765V ENST00000261833 NM_007174.2 765 gCg/gTg 0 +CLASRP UCSF GRCh37 19 45563647 45563647 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 30 37 0 ENST00000221455.3:c.711G>A p.Arg237= p.R237= ENST00000221455 NM_007056.2 237 agG/agA 0 +CLCA4 UCSF GRCh37 1 87041026 87041026 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 33 67 0 ENST00000370563.3:c.1695G>A p.Trp565Ter p.W565* ENST00000370563 NM_012128.3 565 tgG/tgA 0 +CLCN2 UCSF GRCh37 3 184071508 184071508 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 9 9 0 ENST00000265593.4:c.1797C>T p.Asp599= p.D599= ENST00000265593 NM_004366.5 599 gaC/gaT 0 +CLCN6 UCSF GRCh37 1 11897461 11897461 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 120 66 71 0 ENST00000346436.6:c.2200G>A p.Glu734Lys p.E734K ENST00000346436 NM_001286.3 734 Gag/Aag 0 +CLCN7 UCSF GRCh37 16 1505749 1505749 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 44 21 35 0 ENST00000382745.4:c.964T>C p.Phe322Leu p.F322L ENST00000382745 NM_001287.5 322 Ttc/Ctc 0 +CLDN12 UCSF GRCh37 7 90042082 90042082 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 152 52 97 0 ENST00000287916.4:c.92C>T p.Pro31Leu p.P31L ENST00000287916 NM_001185073.2 31 cCc/cTc 0 +CLDN14 UCSF GRCh37 21 37833860 37833860 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 13 12 0 ENST00000342108.2:c.134C>T p.Ser45Phe p.S45F ENST00000342108 NM_001146077.1 45 tCc/tTc 0 +CLDN25 UCSF GRCh37 11 113651156 113651156 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 44 57 0 ENST00000453129.2:c.639G>A p.Glu213= p.E213= ENST00000453129 NM_001101389.1 213 gaG/gaA 0 +CLDN3 UCSF GRCh37 7 73183997 73183997 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 24 14 0 ENST00000395145.2:c.383C>T p.Ala128Val p.A128V ENST00000395145 NM_001306.3 128 gCc/gTc 0 +CLEC14A UCSF GRCh37 14 38723923 38723923 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 46 61 0 ENST00000342213.2:c.1305G>A p.Lys435= p.K435= ENST00000342213 NM_175060.2 435 aaG/aaA 0 +CLEC4F UCSF GRCh37 2 71046551 71046551 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 5 28 0 ENST00000272367.2:c.204G>A p.Pro68= p.P68= ENST00000272367 NM_001258027.1 68 ccG/ccA 0 +CLIC2 UCSF GRCh37 X 154528171 154528171 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 20 46 56 0 ENST00000369449.2:c.220G>A p.Val74Met p.V74M ENST00000369449 NM_001289.4 74 Gtg/Atg 0 +CLIC3 UCSF GRCh37 9 139889703 139889703 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 30 13 0 ENST00000494426.1:c.311C>T p.Ala104Val p.A104V ENST00000494426 NM_004669.2 104 gCc/gTc 0 +CLIP1 UCSF GRCh37 12 122825965 122825965 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 167 57 143 0 ENST00000540338.1:c.1786G>A p.Glu596Lys p.E596K ENST00000540338 596 Gaa/Aaa 0 +CLMN UCSF GRCh37 14 95688111 95688111 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 12 40 0 ENST00000298912.4:c.241C>T p.Leu81= p.L81= ENST00000298912 NM_024734.3 81 Ctg/Ttg 0 +CLOCK UCSF GRCh37 4 56308688 56308688 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 29 45 0 ENST00000309964.4:c.2016C>T p.Ala672= p.A672= ENST00000309964 NM_004898.3 672 gcC/gcT 0 +CLPB UCSF GRCh37 11 72012915 72012915 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 96 136 0 ENST00000294053.3:c.1351G>A p.Val451Met p.V451M ENST00000294053 NM_001258394.1 451 Gtg/Atg 0 +CLPTM1L UCSF GRCh37 5 1339018 1339018 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 43 30 0 ENST00000320895.5:c.556G>A p.Asp186Asn p.D186N ENST00000320895 NM_030782.3 186 Gac/Aac 0 +CLPX UCSF GRCh37 15 65459022 65459022 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 68 111 0 ENST00000300107.3:c.460G>A p.Ala154Thr p.A154T ENST00000300107 NM_006660.3 154 Gca/Aca 0 +CLTCL1 UCSF GRCh37 22 19222138 19222138 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 59 133 0 ENST00000427926.1:c.1061G>A p.Arg354His p.R354H ENST00000427926 354 cGt/cAt 0 +CMTM7 UCSF GRCh37 3 32493943 32493943 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 135 42 112 0 ENST00000334983.5:c.492C>G p.Ile164Met p.I164M ENST00000334983 NM_138410.2 164 atC/atG 0 +CNGA1 UCSF GRCh37 4 47939410 47939410 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 77 163 0 ENST00000358519.4:c.1101C>T p.Pro367= p.P367= ENST00000358519 367 ccC/ccT 0 +CNGB1 UCSF GRCh37 16 57921761 57921761 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 52 70 0 ENST00000251102.8:c.3460C>T p.Gln1154Ter p.Q1154* ENST00000251102 NM_001297.4 1154 Cag/Tag 0 +CNKSR1 UCSF GRCh37 1 26510576 26510576 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 51 36 59 0 ENST00000374253.5:c.891C>T p.Val297= p.V297= ENST00000374253 NM_006314.2 297 gtC/gtT 0 +CNOT10 UCSF GRCh37 3 32761616 32761616 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 32 50 0 ENST00000328834.5:c.755C>T p.Ser252Phe p.S252F ENST00000328834 NM_015442.2 252 tCt/tTt 0 +CNOT2 UCSF GRCh37 12 70739975 70739975 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 32 74 0 ENST00000229195.3:c.1407G>A p.Trp469Ter p.W469* ENST00000229195 NM_014515.5 469 tgG/tgA 0 +CNTN4 UCSF GRCh37 3 2967424 2967424 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 120 64 110 0 ENST00000397461.1:c.1319C>T p.Thr440Ile p.T440I ENST00000397461 NM_001206955.1 440 aCc/aTc 0 +CNTNAP2 UCSF GRCh37 7 147092808 147092808 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 69 97 0 ENST00000361727.3:c.1606G>A p.Val536Met p.V536M ENST00000361727 NM_014141.5 536 Gtg/Atg 0 +CNTNAP2 UCSF GRCh37 7 146471385 146471385 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 9 18 0 ENST00000361727.3:c.120C>T p.Val40= p.V40= ENST00000361727 NM_014141.5 40 gtC/gtT 0 +CNTNAP3 UCSF GRCh37 9 39109170 39109170 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 43 127 0 ENST00000297668.6:c.2352C>T p.Leu784= p.L784= ENST00000297668 NM_033655.3 784 ctC/ctT 0 +CNTRL UCSF GRCh37 9 123922424 123922424 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 35 52 0 ENST00000238341.5:c.4933G>A p.Val1645Ile p.V1645I ENST00000238341 NM_007018.4 1645 Gta/Ata 0 +COG7 UCSF GRCh37 16 23409437 23409437 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 12 26 0 ENST00000307149.5:c.1817C>T p.Ala606Val p.A606V ENST00000307149 NM_153603.3 606 gCt/gTt 0 +COL11A1 UCSF GRCh37 1 103467488 103467488 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 27 62 0 ENST00000370096.3:c.2135G>A p.Gly712Asp p.G712D ENST00000370096 NM_001854.3 712 gGt/gAt 0 +COL11A2 UCSF GRCh37 6 33156946 33156946 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 20 43 0 ENST00000374708.4:c.252C>T p.Phe84= p.F84= ENST00000374708 NM_080681.2 84 ttC/ttT 0 +COL15A1 UCSF GRCh37 9 101785659 101785659 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 5 9 0 ENST00000375001.3:c.1782C>T p.Gly594= p.G594= ENST00000375001 NM_001855.4 594 ggC/ggT 0 +COL16A1 UCSF GRCh37 1 32120459 32120459 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 149 82 107 0 ENST00000373672.3:c.4291G>A p.Gly1431Arg p.G1431R ENST00000373672 NM_001856.3 1431 Gga/Aga 0 +COL1A1 UCSF GRCh37 17 48271324 48271324 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 24 49 0 ENST00000225964.5:c.1747C>T p.Pro583Ser p.P583S ENST00000225964 NM_000088.3 583 Cct/Tct 0 +COL28A1 UCSF GRCh37 7 7400059 7400059 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 18 51 0 ENST00000399429.3:c.3167C>T p.Pro1056Leu p.P1056L ENST00000399429 NM_001037763.2 1056 cCc/cTc 0 +COL2A1 UCSF GRCh37 12 48388219 48388219 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 7 23 0 ENST00000380518.3:c.804G>A p.Pro268= p.P268= ENST00000380518 NM_033150.2 268 ccG/ccA 0 +COL3A1 UCSF GRCh37 2 189855065 189855065 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 16 37 0 ENST00000304636.3:c.777C>T p.Phe259= p.F259= ENST00000304636 NM_000090.3 259 ttC/ttT 0 +COL5A1 UCSF GRCh37 9 137646141 137646141 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 30 35 0 ENST00000371817.3:c.1796C>T p.Pro599Leu p.P599L ENST00000371817 NM_001278074.1 599 cCg/cTg 0 +COL5A1 UCSF GRCh37 9 137727017 137727017 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 19 16 0 ENST00000371817.3:c.5337C>T p.Asn1779= p.N1779= ENST00000371817 NM_001278074.1 1779 aaC/aaT 0 +COL5A2 UCSF GRCh37 2 189928723 189928723 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 14 15 0 ENST00000374866.3:c.1753G>A p.Gly585Arg p.G585R ENST00000374866 NM_000393.3 585 Gga/Aga 0 +COL5A3 UCSF GRCh37 19 10116849 10116849 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 18 14 0 ENST00000264828.3:c.147G>A p.Glu49= p.E49= ENST00000264828 NM_015719.3 49 gaG/gaA 0 +COL7A1 UCSF GRCh37 3 48618048 48618048 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 14 17 0 ENST00000328333.8:c.5018G>A p.Gly1673Glu p.G1673E ENST00000328333 NM_000094.3 1673 gGa/gAa 0 +COL7A1 UCSF GRCh37 3 48623045 48623045 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 112 42 80 0 ENST00000328333.8:c.3839C>T p.Thr1280Ile p.T1280I ENST00000328333 NM_000094.3 1280 aCc/aTc 0 +COL7A1 UCSF GRCh37 3 48610990 48610990 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 21 52 0 ENST00000328333.8:c.6574G>A p.Gly2192Ser p.G2192S ENST00000328333 NM_000094.3 2192 Ggt/Agt 0 +COMP UCSF GRCh37 19 18900034 18900034 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 5 9 0 ENST00000222271.2:c.463C>T p.Pro155Ser p.P155S ENST00000222271 NM_000095.2 155 Ccg/Tcg 0 +COPG2 UCSF GRCh37 7 130297051 130297051 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 39 52 0 ENST00000445977.2:c.551C>T p.Ala184Val p.A184V ENST00000445977 184 gCt/gTt 0 +COQ10B UCSF GRCh37 2 198327456 198327456 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 40 92 0 ENST00000263960.2:c.447+1G>A p.X149_splice ENST00000263960 NM_025147.3 0 +CORO1B UCSF GRCh37 11 67210034 67210034 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 56 42 0 ENST00000341356.5:c.66C>T p.Asn22= p.N22= ENST00000341356 NM_020441.2 22 aaC/aaT 0 +CPA1 UCSF GRCh37 7 130024402 130024402 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 31 59 0 ENST00000011292.3:c.722C>T p.Ser241Phe p.S241F ENST00000011292 NM_001868.2 241 tCc/tTc 0 +CPA2 UCSF GRCh37 7 129910532 129910532 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 26 48 0 ENST00000222481.4:c.289-1G>A p.X97_splice ENST00000222481 NM_001869.2 0 +CPA6 UCSF GRCh37 8 68423853 68423853 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 135 83 171 0 ENST00000297770.4:c.355G>A p.Gly119Arg p.G119R ENST00000297770 NM_020361.4 119 Gga/Aga 0 +CPEB2 UCSF GRCh37 4 15067995 15067995 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 24 20 0 ENST00000507071.1:c.1761C>T p.Arg587= p.R587= ENST00000507071 587 cgC/cgT 0 +CPLX4 UCSF GRCh37 18 56963995 56963995 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 15 48 0 ENST00000299721.3:c.418G>A p.Glu140Lys p.E140K ENST00000299721 NM_181654.3 140 Gaa/Aaa 0 +CPN1 UCSF GRCh37 10 101841302 101841302 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 18 36 0 ENST00000370418.3:c.81C>T p.Arg27= p.R27= ENST00000370418 NM_001308.2 27 cgC/cgT 0 +CPNE4 UCSF GRCh37 3 131261584 131261584 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 20 75 0 ENST00000429747.1:c.1356C>T p.Asp452= p.D452= ENST00000429747 NM_130808.1 452 gaC/gaT 0 +CPNE7 UCSF GRCh37 16 89655150 89655150 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 20 18 0 ENST00000268720.5:c.1220C>T p.Pro407Leu p.P407L ENST00000268720 NM_014427.4 407 cCc/cTc 0 +CPNE7 UCSF GRCh37 16 89655121 89655121 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 19 20 0 ENST00000268720.5:c.1191G>A p.Arg397= p.R397= ENST00000268720 NM_014427.4 397 cgG/cgA 0 +CPNE9 UCSF GRCh37 3 9759751 9759751 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 24 62 0 ENST00000383832.3:c.970C>T p.Pro324Ser p.P324S ENST00000383832 NM_153635.2 324 Ccc/Tcc 0 +CPO UCSF GRCh37 2 207827203 207827203 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 52 94 0 ENST00000272852.3:c.642G>A p.Glu214= p.E214= ENST00000272852 NM_173077.2 214 gaG/gaA 0 +CPS1 UCSF GRCh37 2 211540487 211540487 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 30 47 0 ENST00000233072.5:c.4197C>T p.Asn1399= p.N1399= ENST00000233072 NM_001875.4 1399 aaC/aaT 0 +CPSF2 UCSF GRCh37 14 92625468 92625468 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 29 102 0 ENST00000298875.4:c.1963G>A p.Asp655Asn p.D655N ENST00000298875 NM_017437.2 655 Gat/Aat 0 +CPSF3 UCSF GRCh37 2 9568931 9568931 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 32 21 0 ENST00000238112.3:c.88C>T p.Leu30Phe p.L30F ENST00000238112 NM_016207.3 30 Ctc/Ttc 0 +CR2 UCSF GRCh37 1 207644796 207644796 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 28 72 0 ENST00000367058.3:c.1522G>A p.Glu508Lys p.E508K ENST00000367058 NM_001877.4 508 Gag/Aag 0 +CRB1 UCSF GRCh37 1 197297784 197297784 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 29 48 0 ENST00000367400.3:c.303G>A p.Gly101= p.G101= ENST00000367400 NM_201253.2 101 ggG/ggA 0 +CRB2 UCSF GRCh37 9 126133407 126133407 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 195 136 98 0 ENST00000373631.3:c.1986C>T p.Leu662= p.L662= ENST00000373631 NM_173689.5 662 ctC/ctT 0 +CREB3L3 UCSF GRCh37 19 4157196 4157196 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 32 36 0 ENST00000078445.2:c.361G>A p.Gly121Arg p.G121R ENST00000078445 NM_032607.2 121 Ggg/Agg 0 +CREB5 UCSF GRCh37 7 28527801 28527801 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 173 51 96 0 ENST00000357727.2:c.12G>A p.Glu4= p.E4= ENST00000357727 NM_182898.2 4 gaG/gaA 0 +CREBBP UCSF GRCh37 16 3900677 3900677 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 38 40 0 ENST00000262367.5:c.419C>T p.Thr140Ile p.T140I ENST00000262367 NM_004380.2 140 aCc/aTc 0 +CRHR2 UCSF GRCh37 7 30702446 30702446 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 18 25 0 ENST00000471646.1:c.561C>T p.Ile187= p.I187= ENST00000471646 NM_001202483.1 187 atC/atT 0 +CRNN UCSF GRCh37 1 152384651 152384651 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 43 79 0 ENST00000271835.3:c.59G>A p.Arg20Lys p.R20K ENST00000271835 NM_016190.2 20 aGg/aAg 0 +CROCC UCSF GRCh37 1 17263217 17263217 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 17 11 0 ENST00000375541.5:c.1042C>T p.Leu348= p.L348= ENST00000375541 NM_014675.3 348 Ctg/Ttg 0 +CRTC2 UCSF GRCh37 1 153930932 153930932 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 18 9 0 ENST00000368633.1:c.42C>T p.Ala14= p.A14= ENST00000368633 NM_181715.2 14 gcC/gcT 0 +CRTC3 UCSF GRCh37 15 91184367 91184367 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 18 31 0 ENST00000268184.6:c.1587C>T p.Asp529= p.D529= ENST00000268184 529 gaC/gaT 0 +CRYGS UCSF GRCh37 3 186257318 186257318 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 31 38 0 ENST00000307944.5:c.90C>T p.Phe30= p.F30= ENST00000307944 30 ttC/ttT 0 +CSNK1A1L UCSF GRCh37 13 37678549 37678549 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 149 85 162 0 ENST00000379800.3:c.845G>A p.Arg282His p.R282H ENST00000379800 NM_145203.5 282 cGc/cAc 0 +CTBS UCSF GRCh37 1 85020795 85020795 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 45 77 0 ENST00000370630.5:c.1045C>T p.Arg349Trp p.R349W ENST00000370630 NM_004388.2 349 Cgg/Tgg 0 +CTNNA1 UCSF GRCh37 5 138223181 138223181 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 43 98 0 ENST00000302763.7:c.1146C>T p.Leu382= p.L382= ENST00000302763 NM_001903.2 382 ctC/ctT 0 +CTNNA2 UCSF GRCh37 2 79971605 79971605 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 21 33 0 ENST00000402739.4:c.195G>A p.Glu65= p.E65= ENST00000402739 NM_001282597.1 65 gaG/gaA 0 +CTTNBP2 UCSF GRCh37 7 117417811 117417811 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 156 69 0 ENST00000160373.3:c.2532G>A p.Trp844Ter p.W844* ENST00000160373 NM_033427.2 844 tgG/tgA 0 +CTU2 UCSF GRCh37 16 88780546 88780546 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 26 27 0 ENST00000453996.2:c.1008C>T p.Ala336= p.A336= ENST00000453996 NM_001012759.1 336 gcC/gcT 0 +CUBN UCSF GRCh37 10 17126431 17126431 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 33 46 0 ENST00000377833.4:c.2140G>A p.Asp714Asn p.D714N ENST00000377833 NM_001081.3 714 Gac/Aac 0 +CUL9 UCSF GRCh37 6 43155750 43155750 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 18 55 0 ENST00000252050.4:c.1881G>A p.Lys627= p.K627= ENST00000252050 NM_015089.2 627 aaG/aaA 0 +CWC27 UCSF GRCh37 5 64096076 64096076 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 26 55 0 ENST00000381070.3:c.671G>A p.Ser224Asn p.S224N ENST00000381070 NM_005869.2 224 aGc/aAc 0 +CWF19L1 UCSF GRCh37 10 102016038 102016038 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 42 58 0 ENST00000354105.4:c.485G>A p.Gly162Glu p.G162E ENST00000354105 NM_018294.4 162 gGg/gAg 0 +CWH43 UCSF GRCh37 4 49032932 49032932 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 56 110 0 ENST00000226432.4:c.1463G>A p.Gly488Asp p.G488D ENST00000226432 NM_025087.2 488 gGt/gAt 0 +CWH43 UCSF GRCh37 4 49032978 49032978 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 58 117 0 ENST00000226432.4:c.1508+1G>A p.X503_splice ENST00000226432 NM_025087.2 0 +CXXC1 UCSF GRCh37 18 47812419 47812419 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 129 71 58 0 ENST00000285106.6:c.432G>A p.Pro144= p.P144= ENST00000285106 NM_001101654.1 144 ccG/ccA 0 +CYB5R2 UCSF GRCh37 11 7686718 7686718 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 14 19 23 0 ENST00000299498.6:c.718C>T p.Pro240Ser p.P240S ENST00000299498 NM_016229.3 240 Cca/Tca 0 +CYFIP1 UCSF GRCh37 15 22999357 22999357 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 32 41 0 ENST00000313077.7:c.3229G>A p.Glu1077Lys p.E1077K ENST00000313077 NM_014608.2 1077 Gag/Aag 0 +CYHR1 UCSF GRCh37 8 145689659 145689659 + intron_variant Intron DEL C C - NOVEL P05_Rec Untested WXS Illumina HiSeq 6 0 ENST00000438911.2:c.246+184del *82* ENST00000438911 NM_138496.1 0 +CYLC1 UCSF GRCh37 X 83128720 83128720 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 37 80 0 ENST00000329312.4:c.1004C>T p.Ala335Val p.A335V ENST00000329312 NM_021118.2 335 gCt/gTt 0 +CYLC1 UCSF GRCh37 X 83128100 83128100 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 25 41 0 ENST00000329312.4:c.384G>A p.Lys128= p.K128= ENST00000329312 NM_021118.2 128 aaG/aaA 0 +CYP1A1 UCSF GRCh37 15 75013789 75013789 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 31 58 0 ENST00000379727.3:c.1008C>T p.Asn336= p.N336= ENST00000379727 336 aaC/aaT 0 +CYP46A1 UCSF GRCh37 14 100184439 100184439 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 14 51 0 ENST00000261835.3:c.956C>T p.Ser319Phe p.S319F ENST00000261835 NM_006668.1 319 tCt/tTt 0 +CYP4X1 UCSF GRCh37 1 47501585 47501585 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 42 84 0 ENST00000371901.3:c.600G>A p.Glu200= p.E200= ENST00000371901 NM_178033.1 200 gaG/gaA 0 +DAGLA UCSF GRCh37 11 61495691 61495691 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 72 46 0 ENST00000257215.5:c.703G>A p.Asp235Asn p.D235N ENST00000257215 NM_006133.2 235 Gac/Aac 0 +DAO UCSF GRCh37 12 109290787 109290787 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 14 61 0 ENST00000228476.3:c.618C>T p.Asp206= p.D206= ENST00000228476 NM_001917.4 206 gaC/gaT 0 +DAPK1 UCSF GRCh37 9 90252979 90252979 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 25 67 0 ENST00000358077.5:c.406G>A p.Ala136Thr p.A136T ENST00000358077 NM_001288731.1 136 Gcc/Acc 0 +DAXX UCSF GRCh37 6 33289312 33289312 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 94 61 67 0 ENST00000266000.6:c.240C>T p.Asp80= p.D80= ENST00000266000 80 gaC/gaT 0 +DBH UCSF GRCh37 9 136513028 136513028 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0020,snp132_rs75215331 P05_Rec Untested WXS Illumina HiSeq 52 21 30 0 ENST00000393056.2:c.1085C>T p.Ala362Val p.A362V ENST00000393056 NM_000787.3 362 gCg/gTg 0 +DBH UCSF GRCh37 9 136523486 136523486 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 172 61 33 0 ENST00000393056.2:c.1771G>A p.Glu591Lys p.E591K ENST00000393056 NM_000787.3 591 Gag/Aag 0 +DCAF17 UCSF GRCh37 2 172337616 172337616 + missense_variant Missense_Mutation SNP A A T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 47 84 0 ENST00000375255.3:c.1555A>T p.Ser519Cys p.S519C ENST00000375255 NM_025000.3 519 Agc/Tgc 0 +DCAF4 UCSF GRCh37 14 73406608 73406608 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 17 6 12 0 ENST00000358377.2:c.191C>T p.Pro64Leu p.P64L ENST00000358377 NM_001163509.1 64 cCa/cTa 0 +DCAF4 UCSF GRCh37 14 73425453 73425453 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 56 54 0 ENST00000358377.2:c.1428G>A p.Arg476= p.R476= ENST00000358377 NM_001163509.1 476 cgG/cgA 0 +DCAF4L2 UCSF GRCh37 8 88885864 88885864 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 122 66 75 0 ENST00000319675.3:c.336C>T p.Leu112= p.L112= ENST00000319675 NM_152418.3 112 ctC/ctT 0 +DCAF5 UCSF GRCh37 14 69520872 69520872 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 25 41 0 ENST00000341516.5:c.2531C>T p.Pro844Leu p.P844L ENST00000341516 NM_003861.2 844 cCt/cTt 0 +DCAF6 UCSF GRCh37 1 168035641 168035641 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 34 16 0 ENST00000312263.6:c.2350G>A p.Asp784Asn p.D784N ENST00000312263 NM_001017977.2 784 Gac/Aac 0 +DCAF7 UCSF GRCh37 17 61661012 61661012 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 94 57 98 0 ENST00000431926.1:c.435+3801G>A *145* ENST00000431926 0 +DCC UCSF GRCh37 18 50731599 50731599 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 167 86 153 0 ENST00000442544.2:c.1587G>A p.Gly529= p.G529= ENST00000442544 NM_005215.3 529 ggG/ggA 0 +DCHS2 UCSF GRCh37 4 155157309 155157309 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 46 69 0 ENST00000357232.4:c.7130G>A p.Gly2377Glu p.G2377E ENST00000357232 NM_017639.3 2377 gGg/gAg 0 +DDAH2 UCSF GRCh37 6 31696918 31696918 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 79 56 43 0 ENST00000375787.2:c.21G>A p.Gly7= p.G7= ENST00000375787 NM_013974.1 7 ggG/ggA 0 +DDB1 UCSF GRCh37 11 61089873 61089873 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 36 90 0 ENST00000301764.7:c.1017C>T p.Asp339= p.D339= ENST00000301764 NM_001923.4 339 gaC/gaT 0 +DDHD1 UCSF GRCh37 14 53513646 53513646 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 39 34 58 0 ENST00000323669.5:c.2543A>C p.Asp848Ala p.D848A ENST00000323669 NM_001160148.1 848 gAt/gCt 0 +DDN UCSF GRCh37 12 49390988 49390988 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 7 11 0 ENST00000421952.2:c.1671C>T p.Asn557= p.N557= ENST00000421952 NM_015086.1 557 aaC/aaT 0 +DDX10 UCSF GRCh37 11 108547856 108547856 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 51 80 0 ENST00000322536.3:c.423G>A p.Gly141= p.G141= ENST00000322536 NM_004398.2 141 ggG/ggA 0 +DDX11 UCSF GRCh37 12 31237978 31237978 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.161,1000g2011may_all_0.2074,snp132_rs74087925 P05_Rec Untested WXS Illumina HiSeq 37 14 16 1 ENST00000545668.1:c.556C>T p.Arg186Trp p.R186W ENST00000545668 NM_001257144.1 186 Cgg/Tgg 0 +DDX11 UCSF GRCh37 12 31236773 31236773 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 86 122 0 ENST00000545668.1:c.171G>A p.Gly57= p.G57= ENST00000545668 NM_001257144.1 57 ggG/ggA 0 +DDX39A UCSF GRCh37 19 14520440 14520440 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 46 44 1 ENST00000242776.4:c.882G>A p.Lys294= p.K294= ENST00000242776 NM_005804.3 294 aaG/aaA 0 +DDX42 UCSF GRCh37 17 61894274 61894274 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 12 52 0 ENST00000389924.2:c.2060C>T p.Pro687Leu p.P687L ENST00000389924 NM_203499.2 687 cCt/cTt 0 +DDX42 UCSF GRCh37 17 61894288 61894288 + missense_variant Missense_Mutation SNP A A T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 11 47 0 ENST00000389924.2:c.2074A>T p.Met692Leu p.M692L ENST00000389924 NM_203499.2 692 Atg/Ttg 0 +DDX55 UCSF GRCh37 12 124093278 124093278 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 47 103 0 ENST00000238146.4:c.453G>A p.Arg151= p.R151= ENST00000238146 NM_020936.1 151 agG/agA 0 +DEM1 UCSF GRCh37 1 40980565 40980565 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 51 87 0 ENST00000296380.4:c.349G>A p.Gly117Ser p.G117S ENST00000296380 NM_022774.1 117 Ggt/Agt 0 +DENND1A UCSF GRCh37 9 126554866 126554866 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 20 34 0 ENST00000373624.2:c.132G>A p.Gln44= p.Q44= ENST00000373624 NM_020946.1 44 caG/caA 0 +DENND2C UCSF GRCh37 1 115151491 115151491 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 24 71 0 ENST00000393274.1:c.1373G>A p.Arg458His p.R458H ENST00000393274 NM_001256404.1 458 cGc/cAc 0 +DENND3 UCSF GRCh37 8 142175334 142175334 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 47 92 0 ENST00000262585.2:c.1259G>A p.Arg420Lys p.R420K ENST00000262585 NM_014957.2 420 aGg/aAg 0 +DENND3 UCSF GRCh37 8 142151382 142151382 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 44 39 0 ENST00000262585.2:c.342C>T p.Ser114= p.S114= ENST00000262585 NM_014957.2 114 tcC/tcT 0 +DENND4C UCSF GRCh37 9 19372071 19372071 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 73 94 0 ENST00000602925.1:c.5630G>A p.Ser1877Asn p.S1877N ENST00000602925 NM_017925.5 1877 aGt/aAt 0 +DGCR2 UCSF GRCh37 22 19026602 19026602 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 28 26 0 ENST00000263196.7:c.1429C>T p.Leu477= p.L477= ENST00000263196 NM_001184781.1 477 Ctg/Ttg 0 +DHCR7 UCSF GRCh37 11 71149986 71149986 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 37 21 0 ENST00000355527.3:c.770C>T p.Ala257Val p.A257V ENST00000355527 NM_001360.2 257 gCg/gTg 0 +DHRS2 UCSF GRCh37 14 24108207 24108207 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 110 110 71 0 ENST00000250383.6:c.134C>T p.Thr45Ile p.T45I ENST00000250383 NM_005794.3 45 aCc/aTc 0 +DHTKD1 UCSF GRCh37 10 12136143 12136143 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 31 72 0 ENST00000263035.4:c.1231C>T p.Leu411= p.L411= ENST00000263035 NM_018706.6 411 Ctg/Ttg 0 +DHX37 UCSF GRCh37 12 125460028 125460028 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 19 23 0 ENST00000308736.2:c.917C>T p.Pro306Leu p.P306L ENST00000308736 NM_032656.3 306 cCc/cTc 0 +DIAPH1 UCSF GRCh37 5 140953776 140953776 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 20 27 0 ENST00000389054.3:c.1642-1G>A p.X548_splice ENST00000389054 0 +DIDO1 UCSF GRCh37 20 61528154 61528154 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 63 48 0 ENST00000266070.4:c.1783C>T p.Pro595Ser p.P595S ENST00000266070 NM_033081.2 595 Ccc/Tcc 0 +DIO1 UCSF GRCh37 1 54371821 54371821 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 22 40 0 ENST00000361921.3:c.535G>A p.Asp179Asn p.D179N ENST00000361921 NM_213593.3 179 Gat/Aat 0 +DIO3 UCSF GRCh37 14 102027864 102027864 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 18 16 0 ENST00000510508.4:c.31G>A p.Val11Ile p.V11I ENST00000510508 11 Gtc/Atc 0 +DIP2A UCSF GRCh37 21 47978178 47978178 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 32 17 0 ENST00000417564.2:c.3841G>A p.Val1281Ile p.V1281I ENST00000417564 1281 Gtc/Atc 0 +DIP2C UCSF GRCh37 10 518451 518451 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 55 34 0 ENST00000280886.6:c.196G>A p.Val66Ile p.V66I ENST00000280886 NM_014974.2 66 Gtc/Atc 0 +DISC1 UCSF GRCh37 1 232144796 232144796 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 46 74 0 ENST00000439617.2:c.2307+1G>A p.X769_splice ENST00000439617 NM_001164540.1 0 +DLC1 UCSF GRCh37 8 12957327 12957327 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 50 57 0 ENST00000276297.4:c.2519C>T p.Thr840Met p.T840M ENST00000276297 NM_182643.2 840 aCg/aTg 0 +DLG3 UCSF GRCh37 X 69670031 69670031 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 15 18 0 ENST00000374360.3:c.716G>A p.Ser239Asn p.S239N ENST00000374360 NM_021120.3 239 aGc/aAc 0 +DMXL2 UCSF GRCh37 15 51773611 51773611 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 167 89 115 0 ENST00000251076.5:c.5692C>T p.Pro1898Ser p.P1898S ENST00000251076 NM_015263.3 1898 Cct/Tct 0 +DNAAF1 UCSF GRCh37 16 84211350 84211350 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 114 54 44 0 ENST00000378553.5:c.2081C>T p.Ala694Val p.A694V ENST00000378553 NM_178452.4 694 gCc/gTc 0 +DNAH1 UCSF GRCh37 3 52430684 52430684 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.003,1000g2011may_all_0.0054 P05_Rec Untested WXS Illumina HiSeq 88 21 83 0 ENST00000420323.2:c.11481C>T p.Asn3827= p.N3827= ENST00000420323 NM_015512.4 3827 aaC/aaT 0 +DNAH10 UCSF GRCh37 12 124285920 124285920 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 62 102 0 ENST00000409039.3:c.2201C>T p.Ser734Phe p.S734F ENST00000409039 NM_207437.3 734 tCc/tTc 0 +DNAH10 UCSF GRCh37 12 124401178 124401178 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 155 56 99 0 ENST00000409039.3:c.10543G>A p.Glu3515Lys p.E3515K ENST00000409039 NM_207437.3 3515 Gaa/Aaa 0 +DNAH10 UCSF GRCh37 12 124352656 124352656 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 20 33 0 ENST00000409039.3:c.7155G>A p.Gly2385= p.G2385= ENST00000409039 NM_207437.3 2385 ggG/ggA 0 +DNAH12 UCSF GRCh37 3 57356463 57356463 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 111 33 102 0 ENST00000351747.2:c.7828C>T p.Pro2610Ser p.P2610S ENST00000351747 NM_178504.4 2610 Ccc/Tcc 0 +DNAH14 UCSF GRCh37 1 225152200 225152200 + synonymous_variant Silent SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 63 42 60 0 ENST00000445597.2:c.768G>C p.Val256= p.V256= ENST00000445597 256 gtG/gtC 0 +DNAH17 UCSF GRCh37 17 76554320 76554320 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 42 128 0 ENST00000389840.5:c.2048G>A p.Arg683Lys p.R683K ENST00000389840 683 aGa/aAa 0 +DNAH17 UCSF GRCh37 17 76421649 76421649 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 38 17 0 ENST00000389840.5:c.12988C>T p.Leu4330Phe p.L4330F ENST00000389840 4330 Ctc/Ttc 0 +DNAH2 UCSF GRCh37 17 7691239 7691239 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 46 51 0 ENST00000389173.2:c.6665G>A p.Cys2222Tyr p.C2222Y ENST00000389173 NM_020877.2 2222 tGc/tAc 0 +DNAH5 UCSF GRCh37 5 13891220 13891220 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 56 98 0 ENST00000265104.4:c.2442G>A p.Glu814= p.E814= ENST00000265104 NM_001369.2 814 gaG/gaA 0 +DNAH6 UCSF GRCh37 2 84931258 84931258 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 52 105 0 ENST00000237449.6:c.8297C>T p.Ala2766Val p.A2766V ENST00000237449 2766 gCt/gTt 0 +DNAH6 UCSF GRCh37 2 84848345 84848345 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 31 43 0 ENST00000237449.6:c.3823G>A p.Gly1275Ser p.G1275S ENST00000237449 1275 Ggc/Agc 0 +DNAH6 UCSF GRCh37 2 84915694 84915694 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 30 61 0 ENST00000237449.6:c.7269G>A p.Gln2423= p.Q2423= ENST00000237449 2423 caG/caA 0 +DNAH7 UCSF GRCh37 2 196738340 196738340 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 38 71 0 ENST00000312428.6:c.6365C>T p.Ser2122Phe p.S2122F ENST00000312428 NM_018897.2 2122 tCc/tTc 0 +DNAJC18 UCSF GRCh37 5 138755754 138755754 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 39 110 0 ENST00000302060.5:c.940G>A p.Glu314Lys p.E314K ENST00000302060 NM_152686.3 314 Gag/Aag 0 +DNAJC21 UCSF GRCh37 5 34945016 34945016 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 187 109 172 0 ENST00000342382.4:c.1028C>T p.Ala343Val p.A343V ENST00000342382 343 gCc/gTc 0 +DOCK11 UCSF GRCh37 X 117752562 117752562 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 42 82 0 ENST00000276202.7:c.3342C>T p.Phe1114= p.F1114= ENST00000276202 NM_144658.3 1114 ttC/ttT 0 +DOCK4 UCSF GRCh37 7 111387342 111387342 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 240 81 201 0 ENST00000437633.1:c.4547G>A p.Gly1516Asp p.G1516D ENST00000437633 NM_014705.3 1516 gGc/gAc 0 +DOCK4 UCSF GRCh37 7 111382189 111382189 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 161 78 123 0 ENST00000437633.1:c.4651-1G>A p.X1551_splice ENST00000437633 NM_014705.3 0 +DOCK6 UCSF GRCh37 19 11363181 11363181 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 125 68 134 0 ENST00000294618.7:c.354G>A p.Glu118= p.E118= ENST00000294618 NM_020812.3 118 gaG/gaA 0 +DOCK6 UCSF GRCh37 19 11325298 11325298 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 27 61 0 ENST00000294618.7:c.4134C>T p.Ala1378= p.A1378= ENST00000294618 NM_020812.3 1378 gcC/gcT 0 +DOCK6 UCSF GRCh37 19 11339673 11339673 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 13 17 0 ENST00000294618.7:c.2757C>T p.Ser919= p.S919= ENST00000294618 NM_020812.3 919 agC/agT 0 +DOLPP1 UCSF GRCh37 9 131847523 131847523 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 198 66 88 0 ENST00000372546.4:c.300C>T p.Pro100= p.P100= ENST00000372546 NM_020438.4 100 ccC/ccT 0 +DPH5 UCSF GRCh37 1 101458296 101458296 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 34 65 0 ENST00000370109.3:c.531G>A p.Lys177= p.K177= ENST00000370109 NM_001077395.1 177 aaG/aaA 0 +DPP4 UCSF GRCh37 2 162929997 162929997 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 35 36 0 ENST00000360534.3:c.7-1G>A p.X3_splice ENST00000360534 NM_001935.3 0 +DPP6 UCSF GRCh37 7 154679444 154679444 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 224 88 198 0 ENST00000377770.3:c.2304G>A p.Glu768= p.E768= ENST00000377770 768 gaG/gaA 0 +DPYD UCSF GRCh37 1 97544641 97544641 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 67 135 0 ENST00000370192.3:c.2969C>T p.Thr990Ile p.T990I ENST00000370192 NM_000110.3 990 aCt/aTt 0 +DRAP1 UCSF GRCh37 11 65688075 65688075 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 43 25 0 ENST00000312515.2:c.365G>A p.Gly122Asp p.G122D ENST00000312515 NM_006442.3 122 gGt/gAt 0 +DRD5 UCSF GRCh37 4 9784541 9784541 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 147 80 62 0 ENST00000304374.2:c.888G>A p.Lys296= p.K296= ENST00000304374 NM_000798.4 296 aaG/aaA 0 +DRG2 UCSF GRCh37 17 18005276 18005276 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 11 14 0 ENST00000225729.3:c.771C>T p.Asp257= p.D257= ENST00000225729 NM_001388.4 257 gaC/gaT 0 +DSC2 UCSF GRCh37 18 28672242 28672242 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 30 70 0 ENST00000280904.6:c.176C>T p.Thr59Ile p.T59I ENST00000280904 NM_024422.3 59 aCa/aTa 0 +DSCR6 UCSF GRCh37 21 38390293 38390293 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 15 27 0 ENST00000329553.2:c.359C>T p.Ala120Val p.A120V ENST00000329553 NM_018962.2 120 gCt/gTt 0 +DSG2 UCSF GRCh37 18 29121213 29121213 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 24 47 0 ENST00000261590.8:c.1937C>T p.Pro646Leu p.P646L ENST00000261590 NM_001943.3 646 cCc/cTc 0 +DST UCSF GRCh37 6 56362671 56362671 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 131 62 141 0 ENST00000244364.6:c.12208G>A p.Asp4070Asn p.D4070N ENST00000244364 NM_015548.4 4070 Gat/Aat 0 +DST UCSF GRCh37 6 56365995 56365995 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 129 64 136 0 ENST00000244364.6:c.11910C>T p.Phe3970= p.F3970= ENST00000244364 NM_015548.4 3970 ttC/ttT 0 +DTNA UCSF GRCh37 18 32455243 32455243 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 24 47 0 ENST00000399113.3:c.1703C>T p.Thr568Ile p.T568I ENST00000399113 568 aCc/aTc 0 +DTX1 UCSF GRCh37 12 113496108 113496108 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 25 16 0 ENST00000257600.3:c.111G>A p.Trp37Ter p.W37* ENST00000257600 NM_004416.2 37 tgG/tgA 0 +DTX2 UCSF GRCh37 7 76132849 76132849 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 21 48 0 ENST00000324432.5:c.1496G>A p.Gly499Asp p.G499D ENST00000324432 NM_020892.2 499 gGc/gAc 0 +DUOX1 UCSF GRCh37 15 45434294 45434294 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 31 50 0 ENST00000321429.4:c.1806C>T p.Leu602= p.L602= ENST00000321429 NM_017434.3 602 ctC/ctT 0 +DUOXA2 UCSF GRCh37 15 45408829 45408829 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 59 24 0 ENST00000323030.5:c.456C>T p.Asp152= p.D152= ENST00000323030 NM_207581.3 152 gaC/gaT 0 +DUSP16 UCSF GRCh37 12 12633232 12633232 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 44 91 0 ENST00000298573.4:c.*144G>A *48* ENST00000298573 0 +DVL1 UCSF GRCh37 1 1273693 1273693 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 31 21 0 ENST00000378888.5:c.1463C>T p.Thr488Ile p.T488I ENST00000378888 488 aCc/aTc 0 +DVL3 UCSF GRCh37 3 183887949 183887949 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 26 24 0 ENST00000313143.3:c.1654G>A p.Gly552Ser p.G552S ENST00000313143 NM_004423.3 552 Ggc/Agc 0 +DYNC1H1 UCSF GRCh37 14 102515847 102515847 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 45 27 0 ENST00000360184.4:c.13443C>T p.Asp4481= p.D4481= ENST00000360184 NM_001376.4 4481 gaC/gaT 0 +DYRK4 UCSF GRCh37 12 4719397 4719397 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 26 61 0 ENST00000010132.5:c.1092G>A p.Met364Ile p.M364I ENST00000010132 364 atG/atA 0 +DZIP1 UCSF GRCh37 13 96239920 96239920 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 33 49 0 ENST00000347108.3:c.2091C>T p.Ser697= p.S697= ENST00000347108 697 tcC/tcT 0 +E2F7 UCSF GRCh37 12 77417858 77417858 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 29 67 0 ENST00000322886.7:c.2673C>T p.Asn891= p.N891= ENST00000322886 NM_203394.2 891 aaC/aaT 0 +ECM1 UCSF GRCh37 1 150483675 150483675 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 104 53 84 0 ENST00000369047.4:c.708+1G>A p.X236_splice ENST00000369047 NM_004425.3 0 +ECT2L UCSF GRCh37 6 139164281 139164281 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 36 85 0 ENST00000367682.2:c.508C>T p.Pro170Ser p.P170S ENST00000367682 NM_001077706.2 170 Ccc/Tcc 0 +EDEM1 UCSF GRCh37 3 5252860 5252860 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 195 70 126 0 ENST00000256497.4:c.1639G>A p.Glu547Lys p.E547K ENST00000256497 NM_014674.2 547 Gag/Aag 0 +EDEM3 UCSF GRCh37 1 184679682 184679682 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 40 82 0 ENST00000318130.8:c.1692-1G>A p.X564_splice ENST00000318130 NM_025191.3 0 +EDF1 UCSF GRCh37 9 139758304 139758304 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 27 63 0 ENST00000224073.1:c.98G>A p.Arg33Lys p.R33K ENST00000224073 NM_001281298.1 33 aGa/aAa 0 +EEA1 UCSF GRCh37 12 93196237 93196237 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 33 38 0 ENST00000322349.8:c.2613C>T p.Asn871= p.N871= ENST00000322349 NM_003566.3 871 aaC/aaT 0 +EFNA1 UCSF GRCh37 1 155106219 155106219 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 58 79 0 ENST00000368407.3:c.468G>A p.Gln156= p.Q156= ENST00000368407 NM_004428.2 156 caG/caA 0 +EFNB2 UCSF GRCh37 13 107145608 107145608 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 66 57 0 ENST00000245323.4:c.782C>T p.Pro261Leu p.P261L ENST00000245323 NM_004093.3 261 cCg/cTg 0 +EHMT1 UCSF GRCh37 9 140672342 140672342 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 254 89 112 0 ENST00000460843.1:c.2027G>A p.Gly676Glu p.G676E ENST00000460843 NM_024757.4 676 gGg/gAg 0 +EHMT1 UCSF GRCh37 9 140652417 140652417 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 57 74 0 ENST00000460843.1:c.1455C>T p.Asp485= p.D485= ENST00000460843 NM_024757.4 485 gaC/gaT 0 +EHMT2 UCSF GRCh37 6 31864759 31864759 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 148 18 47 0 ENST00000375537.4:c.50C>A p.Ala17Asp p.A17D ENST00000375537 NM_006709.3 17 gCc/gAc 0 +EI24 UCSF GRCh37 11 125445200 125445200 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 6 16 0 ENST00000278903.6:c.84G>A p.Lys28= p.K28= ENST00000278903 NM_004879.3 28 aaG/aaA 0 +EIF2AK1 UCSF GRCh37 7 6066478 6066478 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 46 98 0 ENST00000199389.6:c.1645C>T p.Leu549Phe p.L549F ENST00000199389 NM_001134335.1 549 Ctc/Ttc 0 +EIF2S2 UCSF GRCh37 20 32693260 32693260 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 44 94 0 ENST00000374980.2:c.107C>T p.Thr36Ile p.T36I ENST00000374980 NM_003908.3 36 aCc/aTc 0 +EIF3B UCSF GRCh37 7 2418387 2418387 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 27 6 30 0 ENST00000360876.4:c.2218T>C p.Ser740Pro p.S740P ENST00000360876 NM_001037283.1 740 Tcc/Ccc 0 +EIF3K UCSF GRCh37 19 39123092 39123092 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 147 64 153 0 ENST00000248342.4:c.377A>G p.Asp126Gly p.D126G ENST00000248342 NM_013234.2 126 gAc/gGc 0 +EIF6 UCSF GRCh37 20 33872225 33872225 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 201 101 39 0 ENST00000374436.3:c.66C>T p.Thr22= p.T22= ENST00000374436 NM_181468.2 22 acC/acT 0 +ELL UCSF GRCh37 19 18569095 18569095 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 23 36 0 ENST00000262809.4:c.789C>T p.Asp263= p.D263= ENST00000262809 NM_006532.3 263 gaC/gaT 0 +ELMO1 UCSF GRCh37 7 37251060 37251060 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 23 63 0 ENST00000310758.4:c.1017C>T p.Asn339= p.N339= ENST00000310758 NM_014800.10 339 aaC/aaT 0 +EMILIN2 UCSF GRCh37 18 2913251 2913251 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 48 31 39 0 ENST00000254528.3:c.3011G>A p.Gly1004Asp p.G1004D ENST00000254528 NM_032048.2 1004 gGc/gAc 0 +EML5 UCSF GRCh37 14 89160752 89160752 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 46 92 0 ENST00000380664.5:c.2439-1G>A p.X813_splice ENST00000380664 0 +ENAM UCSF GRCh37 4 71508053 71508053 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 41 90 0 ENST00000396073.3:c.910G>A p.Gly304Arg p.G304R ENST00000396073 NM_031889.2 304 Gga/Aga 0 +ENAM UCSF GRCh37 4 71508405 71508405 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 110 78 103 0 ENST00000396073.3:c.1262G>A p.Gly421Asp p.G421D ENST00000396073 NM_031889.2 421 gGt/gAt 0 +ENC1 UCSF GRCh37 5 73931072 73931072 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 28 39 0 ENST00000302351.4:c.1239G>A p.Gln413= p.Q413= ENST00000302351 NM_003633.3 413 caG/caA 0 +ENO2 UCSF GRCh37 12 7030820 7030820 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 43 72 0 ENST00000229277.1:c.942G>A p.Gln314= p.Q314= ENST00000229277 NM_001975.2 314 caG/caA 0 +ENPEP UCSF GRCh37 4 111452380 111452380 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 20 24 0 ENST00000265162.5:c.1754G>A p.Trp585Ter p.W585* ENST00000265162 NM_001977.3 585 tGg/tAg 0 +ENPP2 UCSF GRCh37 8 120569856 120569856 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 57 61 0 ENST00000075322.6:c.2497C>T p.Leu833Phe p.L833F ENST00000075322 NM_001040092.2 833 Ctc/Ttc 0 +ENPP7 UCSF GRCh37 17 77707389 77707389 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 28 27 0 ENST00000328313.5:c.337C>T p.Leu113= p.L113= ENST00000328313 NM_178543.3 113 Ctg/Ttg 0 +EP400 UCSF GRCh37 12 132466904 132466904 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 152 57 53 0 ENST00000389561.2:c.1810C>T p.Pro604Ser p.P604S ENST00000389561 NM_015409.4 604 Cct/Tct 0 +EPB41L1 UCSF GRCh37 20 34785820 34785820 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 27 32 0 ENST00000338074.2:c.1525G>A p.Ala509Thr p.A509T ENST00000338074 NM_012156.2 509 Gcc/Acc 0 +EPB41L4B UCSF GRCh37 9 111965992 111965992 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 40 89 0 ENST00000374566.3:c.1897C>T p.Pro633Ser p.P633S ENST00000374566 NM_019114.3 633 Ccg/Tcg 0 +EPB42 UCSF GRCh37 15 43495332 43495332 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 40 62 0 ENST00000441366.2:c.1760G>A p.Arg587Lys p.R587K ENST00000441366 NM_001114134.1 587 aGa/aAa 0 +EPHA10 UCSF GRCh37 1 38192817 38192817 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 24 15 0 ENST00000373048.4:c.1729C>T p.Leu577Phe p.L577F ENST00000373048 NM_001099439.1 577 Ctc/Ttc 0 +EPHA10 UCSF GRCh37 1 38186467 38186467 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 7 20 0 ENST00000373048.4:c.2196C>T p.Asp732= p.D732= ENST00000373048 NM_001099439.1 732 gaC/gaT 0 +EPHA6 UCSF GRCh37 3 96945231 96945231 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 68 123 0 ENST00000389672.5:c.1238C>T p.Ala413Val p.A413V ENST00000389672 NM_001080448.2 413 gCt/gTt 0 +EPM2AIP1 UCSF GRCh37 3 37033850 37033850 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 256 97 124 0 ENST00000322716.5:c.719G>A p.Arg240Lys p.R240K ENST00000322716 NM_014805.3 240 aGa/aAa 0 +EPN2 UCSF GRCh37 17 19232186 19232186 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 31 44 0 ENST00000314728.5:c.1310C>T p.Pro437Leu p.P437L ENST00000314728 NM_014964.4 437 cCc/cTc 0 +EPOR UCSF GRCh37 19 11493890 11493890 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 26 26 0 ENST00000222139.6:c.134G>A p.Arg45Gln p.R45Q ENST00000222139 NM_000121.3 45 cGg/cAg 0 +EPOR UCSF GRCh37 19 11492447 11492447 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 23 13 0 ENST00000222139.6:c.506C>T p.Pro169Leu p.P169L ENST00000222139 NM_000121.3 169 cCg/cTg 0 +EPS8L1 UCSF GRCh37 19 55597464 55597464 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 57 39 0 ENST00000201647.6:c.1554G>A p.Arg518= p.R518= ENST00000201647 NM_133180.2 518 cgG/cgA 0 +EPS8L3 UCSF GRCh37 1 110293937 110293937 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 10 29 0 ENST00000361965.4:c.1600G>A p.Val534Ile p.V534I ENST00000361965 534 Gtc/Atc 0 +ERBB2IP UCSF GRCh37 5 65350348 65350348 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 46 75 0 ENST00000284037.5:c.3202G>A p.Ala1068Thr p.A1068T ENST00000284037 NM_001253697.1 1068 Gca/Aca 0 +ERBB4 UCSF GRCh37 2 212426739 212426739 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 49 71 0 ENST00000342788.4:c.2376C>T p.Ile792= p.I792= ENST00000342788 NM_005235.2 792 atC/atT 0 +ERC2 UCSF GRCh37 3 56330151 56330151 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 207 133 160 0 ENST00000288221.6:c.970G>A p.Asp324Asn p.D324N ENST00000288221 NM_015576.1 324 Gat/Aat 0 +ERCC6 UCSF GRCh37 10 50732465 50732465 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 52 100 0 ENST00000355832.5:c.1011G>A p.Lys337= p.K337= ENST00000355832 NM_000124.3 337 aaG/aaA 0 +ERF UCSF GRCh37 19 42752920 42752920 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 155 107 82 0 ENST00000222329.4:c.1344G>A p.Glu448= p.E448= ENST00000222329 NM_006494.2 448 gaG/gaA 0 +ERG UCSF GRCh37 21 39817432 39817432 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 23 39 0 ENST00000398919.2:c.152C>T p.Thr51Ile p.T51I ENST00000398919 NM_001243428.1 51 aCt/aTt 0 +ERGIC3 UCSF GRCh37 20 34142816 34142816 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 49 62 0 ENST00000348547.2:c.687C>T p.Val229= p.V229= ENST00000348547 NM_015966.2 229 gtC/gtT 0 +ERN1 UCSF GRCh37 17 62130161 62130161 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 34 68 0 ENST00000433197.3:c.2232C>T p.Ser744= p.S744= ENST00000433197 NM_001433.3 744 agC/agT 0 +ESCO1 UCSF GRCh37 18 19147941 19147941 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 39 103 0 ENST00000269214.5:c.1645G>A p.Gly549Ser p.G549S ENST00000269214 NM_052911.2 549 Ggt/Agt 0 +ESF1 UCSF GRCh37 20 13753186 13753186 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 40 63 0 ENST00000202816.1:c.1225C>T p.Pro409Ser p.P409S ENST00000202816 NM_001276380.1 409 Cct/Tct 0 +ESPL1 UCSF GRCh37 12 53677943 53677943 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 47 83 0 ENST00000257934.4:c.3179C>T p.Ser1060Phe p.S1060F ENST00000257934 NM_012291.4 1060 tCt/tTt 0 +ESPL1 UCSF GRCh37 12 53687255 53687255 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 15 31 0 ENST00000257934.4:c.6360G>A p.Arg2120= p.R2120= ENST00000257934 NM_012291.4 2120 cgG/cgA 0 +ESPNL UCSF GRCh37 2 239025622 239025622 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 19 26 0 ENST00000343063.3:c.934G>A p.Glu312Lys p.E312K ENST00000343063 NM_194312.2 312 Gag/Aag 0 +ESR2 UCSF GRCh37 14 64701863 64701863 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 55 9 27 0 ENST00000341099.4:c.1231T>G p.Tyr411Asp p.Y411D ENST00000341099 NM_001437.2 411 Tac/Gac 0 +ESR2 UCSF GRCh37 14 64701834 64701834 + synonymous_variant Silent SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 59 15 36 0 ENST00000341099.4:c.1260T>G p.Ala420= p.A420= ENST00000341099 NM_001437.2 420 gcT/gcG 0 +ESYT3 UCSF GRCh37 3 138189831 138189831 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 21 51 0 ENST00000389567.4:c.1703G>A p.Gly568Asp p.G568D ENST00000389567 NM_031913.3 568 gGc/gAc 0 +EXT2 UCSF GRCh37 11 44193294 44193294 + splice_donor_variant Splice_Site SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 28 59 109 0 ENST00000343631.3:c.1305+2T>C p.X435_splice ENST00000343631 0 +EZH2 UCSF GRCh37 7 148544360 148544360 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 278 87 169 0 ENST00000460911.1:c.31G>A p.Gly11Arg p.G11R ENST00000460911 11 Gga/Aga 0 +F2 UCSF GRCh37 11 46750944 46750944 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 14 26 36 0 ENST00000311907.5:c.1487G>A p.Gly496Glu p.G496E ENST00000311907 NM_000506.3 496 gGa/gAa 0 +F9 UCSF GRCh37 X 138619538 138619538 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 29 29 0 ENST00000218099.2:c.270G>A p.Gln90= p.Q90= ENST00000218099 NM_000133.3 90 caG/caA 0 +FA2H UCSF GRCh37 16 74750431 74750431 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 38 9 11 0 ENST00000219368.3:c.853T>C p.Tyr285His p.Y285H ENST00000219368 NM_024306.4 285 Tac/Cac 0 +FABP7 UCSF GRCh37 6 123104903 123104903 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 44 54 0 ENST00000368444.3:c.390G>A p.Glu130= p.E130= ENST00000368444 NM_001446.3 130 gaG/gaA 0 +FAF2 UCSF GRCh37 5 175919294 175919294 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 34 48 0 ENST00000261942.6:c.444G>A p.Gly148= p.G148= ENST00000261942 NM_014613.2 148 ggG/ggA 0 +FAM109A UCSF GRCh37 12 111801103 111801103 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 12 13 0 ENST00000547838.2:c.129G>A p.Gly43= p.G43= ENST00000547838 43 ggG/ggA 0 +FAM109B UCSF GRCh37 22 42473561 42473561 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 76 45 0 ENST00000321753.3:c.264C>T p.Ala88= p.A88= ENST00000321753 NM_001002034.2 88 gcC/gcT 0 +FAM125A UCSF GRCh37 19 17534588 17534588 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 22 24 0 ENST00000317040.7:c.620C>T p.Ser207Phe p.S207F ENST00000317040 207 tCc/tTc 0 +FAM178A UCSF GRCh37 10 102676714 102676714 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 42 76 0 ENST00000238961.4:c.572G>A p.Gly191Asp p.G191D ENST00000238961 NM_018121.3 191 gGc/gAc 0 +FAM179B UCSF GRCh37 14 45432024 45432024 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 69 63 0 ENST00000361577.3:c.400G>A p.Glu134Lys p.E134K ENST00000361577 NM_015091.2 134 Gaa/Aaa 0 +FAM186B UCSF GRCh37 12 49993278 49993278 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 17 31 0 ENST00000257894.2:c.2145C>T p.Ile715= p.I715= ENST00000257894 NM_032130.2 715 atC/atT 0 +FAM190A UCSF GRCh37 4 91229440 91229440 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 25 50 0 ENST00000509176.1:c.5G>A p.Gly2Glu p.G2E ENST00000509176 NM_001145065.1 2 gGg/gAg 0 +FAM198A UCSF GRCh37 3 43073791 43073791 + synonymous_variant,NMD_transcript_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 28 23 0 ENST00000273146.2:c.36G>A p.Lys12= p.K12= ENST00000273146 12 aaG/aaA 0 +FAM19A3 UCSF GRCh37 1 113266678 113266678 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 39 20 24 0 ENST00000361886.3:c.309C>T p.Cys103= p.C103= ENST00000361886 NM_001004440.1 103 tgC/tgT 0 +FAM208A UCSF GRCh37 3 56675640 56675640 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 57 105 0 ENST00000493960.2:c.2356G>A p.Asp786Asn p.D786N ENST00000493960 NM_001112736.1 786 Gat/Aat 0 +FAM208B UCSF GRCh37 10 5772723 5772723 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 134 85 124 0 ENST00000328090.5:c.761C>T p.Ser254Leu p.S254L ENST00000328090 NM_017782.4 254 tCa/tTa 0 +FAM20B UCSF GRCh37 1 179013332 179013332 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 23 42 0 ENST00000263733.4:c.350G>A p.Gly117Asp p.G117D ENST00000263733 NM_014864.3 117 gGc/gAc 0 +FAM46D UCSF GRCh37 X 79698982 79698982 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 51 104 0 ENST00000308293.5:c.944G>A p.Ser315Asn p.S315N ENST00000308293 NM_152630.4 315 aGt/aAt 0 +FAM50B UCSF GRCh37 6 3850294 3850294 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 31 8 0 ENST00000380272.3:c.249G>A p.Glu83= p.E83= ENST00000380272 NM_012135.1 83 gaG/gaA 0 +FAM54B UCSF GRCh37 1 26156015 26156015 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 157 19 129 0 ENST00000374300.3:c.467C>T p.Thr156Met p.T156M ENST00000374300 NM_001099626.1 156 aCg/aTg 0 +FAM65A UCSF GRCh37 16 67573757 67573757 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 278 97 114 0 ENST00000379312.3:c.381G>A p.Lys127= p.K127= ENST00000379312 NM_001193522.1 127 aaG/aaA 0 +FAM78A UCSF GRCh37 9 134136293 134136293 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 116 57 44 0 ENST00000372271.3:c.768G>A p.Lys256= p.K256= ENST00000372271 NM_033387.3 256 aaG/aaA 0 +FAM90A1 UCSF GRCh37 12 8375120 8375120 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 225 93 102 0 ENST00000307435.6:c.693C>T p.Ser231= p.S231= ENST00000307435 231 agC/agT 0 +FANCD2 UCSF GRCh37 3 10091058 10091058 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 218 35 174 0 ENST00000383807.1:c.1414G>A p.Glu472Lys p.E472K ENST00000383807 NM_001018115.1 472 Gaa/Aaa 0 +FANCE UCSF GRCh37 6 35423814 35423814 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 24 26 0 ENST00000229769.2:c.539C>T p.Ser180Phe p.S180F ENST00000229769 NM_021922.2 180 tCc/tTc 0 +FAR2 UCSF GRCh37 12 29423433 29423433 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 13 48 0 ENST00000182377.4:c.51G>A p.Gly17= p.G17= ENST00000182377 NM_018099.4 17 ggG/ggA 0 +FASLG UCSF GRCh37 1 172634901 172634901 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 54 97 0 ENST00000367721.2:c.591C>T p.Phe197= p.F197= ENST00000367721 NM_000639.1 197 ttC/ttT 0 +FAT3 UCSF GRCh37 11 92531204 92531204 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 212 121 202 0 ENST00000298047.6:c.5025C>T p.Asp1675= p.D1675= ENST00000298047 1675 gaC/gaT 0 +FAT4 UCSF GRCh37 4 126371035 126371035 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 22 73 0 ENST00000394329.3:c.8864C>T p.Ser2955Phe p.S2955F ENST00000394329 NM_024582.4 2955 tCt/tTt 0 +FBN1 UCSF GRCh37 15 48786449 48786449 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 31 50 0 ENST00000316623.5:c.2680C>T p.Pro894Ser p.P894S ENST00000316623 NM_000138.4 894 Ccc/Tcc 0 +FBN2 UCSF GRCh37 5 127680179 127680179 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 25 87 0 ENST00000262464.4:c.3241C>T p.Pro1081Ser p.P1081S ENST00000262464 NM_001999.3 1081 Cct/Tct 0 +FBN3 UCSF GRCh37 19 8160848 8160848 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 27 28 0 ENST00000270509.2:c.5656G>A p.Asp1886Asn p.D1886N ENST00000270509 NM_032447.3 1886 Gat/Aat 0 +FBXL6 UCSF GRCh37 8 145580259 145580259 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 49 25 0 ENST00000331890.5:c.993+1G>A p.X331_splice ENST00000331890 NM_012162.3 0 +FBXO30 UCSF GRCh37 6 146121445 146121445 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 41 66 0 ENST00000237281.4:c.2035G>A p.Val679Ile p.V679I ENST00000237281 NM_032145.4 679 Gta/Ata 0 +FBXO39 UCSF GRCh37 17 6690152 6690152 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 27 68 0 ENST00000321535.4:c.1077C>T p.His359= p.H359= ENST00000321535 NM_153230.2 359 caC/caT 0 +FBXO41 UCSF GRCh37 2 73493648 73493648 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 12 11 0 ENST00000295133.5:c.1251C>T p.Ala417= p.A417= ENST00000295133 NM_001080410.2 417 gcC/gcT 0 +FBXO47 UCSF GRCh37 17 37099972 37099972 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 25 64 0 ENST00000378079.2:c.811G>A p.Glu271Lys p.E271K ENST00000378079 NM_001008777.2 271 Gaa/Aaa 0 +FBXO7 UCSF GRCh37 22 32891500 32891500 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 20 30 0 ENST00000266087.7:c.1165G>A p.Asp389Asn p.D389N ENST00000266087 NM_012179.3 389 Gac/Aac 0 +FCGBP UCSF GRCh37 19 40366336 40366336 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 35 24 0 ENST00000221347.6:c.13898G>A p.Gly4633Glu p.G4633E ENST00000221347 NM_003890.2 4633 gGa/gAa 0 +FCGBP UCSF GRCh37 19 40412068 40412068 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 19 18 0 ENST00000221347.6:c.3560C>T p.Ala1187Val p.A1187V ENST00000221347 NM_003890.2 1187 gCc/gTc 0 +FCGRT UCSF GRCh37 19 50017164 50017164 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 65 96 0 ENST00000221466.5:c.99C>T p.His33= p.H33= ENST00000221466 NM_001136019.2 33 caC/caT 0 +FCRL2 UCSF GRCh37 1 157740198 157740198 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 32 72 0 ENST00000361516.3:c.310+1G>A p.X104_splice ENST00000361516 NM_030764.3 0 +FDXACB1 UCSF GRCh37 11 111747557 111747557 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 75 106 0 ENST00000260257.4:c.508G>A p.Ala170Thr p.A170T ENST00000260257 NM_138378.2 170 Gca/Aca 0 +FERMT1 UCSF GRCh37 20 6078170 6078170 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 37 67 0 ENST00000217289.4:c.957+1G>A p.X319_splice ENST00000217289 NM_017671.4 0 +FEZF1 UCSF GRCh37 7 121942396 121942396 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 138 54 73 0 ENST00000442488.2:c.1083C>T p.Asn361= p.N361= ENST00000442488 NM_001160264.1 361 aaC/aaT 0 +FFAR2 UCSF GRCh37 19 35941013 35941013 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 49 61 0 ENST00000246549.2:c.397G>A p.Ala133Thr p.A133T ENST00000246549 NM_005306.2 133 Gcc/Acc 0 +FGD2 UCSF GRCh37 6 36995279 36995279 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 69 66 0 ENST00000274963.8:c.1680G>A p.Lys560= p.K560= ENST00000274963 NM_173558.3 560 aaG/aaA 0 +FGD4 UCSF GRCh37 12 32778605 32778605 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 45 21 64 0 ENST00000427716.2:c.1653A>G p.Lys551= p.K551= ENST00000427716 NM_139241.2 551 aaA/aaG 0 +FGFBP1 UCSF GRCh37 4 15937893 15937893 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 50 90 0 ENST00000382333.1:c.363C>T p.Arg121= p.R121= ENST00000382333 NM_005130.4 121 cgC/cgT 0 +FGFBP2 UCSF GRCh37 4 15964200 15964200 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 49 74 0 ENST00000259989.6:c.553C>T p.Pro185Ser p.P185S ENST00000259989 NM_031950.3 185 Cct/Tct 0 +FGFR2 UCSF GRCh37 10 123276956 123276956 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 36 58 0 ENST00000358487.5:c.961G>A p.Asp321Asn p.D321N ENST00000358487 NM_000141.4 321 Gac/Aac 0 +FHL3 UCSF GRCh37 1 38463171 38463171 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 35 39 0 ENST00000373016.3:c.749C>T p.Ser250Phe p.S250F ENST00000373016 NM_001243878.1 250 tCc/tTc 0 +FITM2 UCSF GRCh37 20 42935321 42935321 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 26 72 0 ENST00000396825.3:c.733G>A p.Gly245Arg p.G245R ENST00000396825 NM_001080472.1 245 Gga/Aga 0 +FLG2 UCSF GRCh37 1 152330054 152330054 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 23 39 0 ENST00000388718.5:c.208G>A p.Asp70Asn p.D70N ENST00000388718 NM_001014342.2 70 Gac/Aac 0 +FLNA UCSF GRCh37 X 153590825 153590825 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 75 41 0 ENST00000369850.3:c.2526G>A p.Gly842= p.G842= ENST00000369850 NM_001110556.1 842 ggG/ggA 0 +FLNC UCSF GRCh37 7 128487825 128487825 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 51 35 0 ENST00000325888.8:c.4363G>A p.Ala1455Thr p.A1455T ENST00000325888 NM_001458.4 1455 Gct/Act 0 +FLNC UCSF GRCh37 7 128494664 128494664 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 11 9 0 ENST00000325888.8:c.6925C>T p.Leu2309= p.L2309= ENST00000325888 NM_001458.4 2309 Ctg/Ttg 0 +FLNC UCSF GRCh37 7 128490857 128490857 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 35 50 0 ENST00000325888.8:c.5399G>A p.Gly1800Glu p.G1800E ENST00000325888 NM_001458.4 1800 gGa/gAa 0 +FLOT2 UCSF GRCh37 17 27208323 27208323 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 44 69 0 ENST00000394908.4:c.985G>A p.Val329Ile p.V329I ENST00000394908 NM_004475.2 329 Gtc/Atc 0 +FLRT2 UCSF GRCh37 14 86089009 86089009 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 39 81 0 ENST00000330753.4:c.1151C>T p.Pro384Leu p.P384L ENST00000330753 NM_013231.4 384 cCc/cTc 0 +FMN1 UCSF GRCh37 15 33358853 33358853 + intron_variant Intron SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 47 126 0 ENST00000559047.1:c.2044-1578G>A *682* ENST00000559047 NM_001277313.1 0 +FMNL2 UCSF GRCh37 2 153468012 153468012 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 106 69 98 0 ENST00000288670.9:c.955G>A p.Ala319Thr p.A319T ENST00000288670 NM_052905.3 319 Gct/Act 0 +FOLH1B UCSF GRCh37 11 89429802 89429802 + splice_region_variant,non_coding_transcript_exon_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 17 34 0 ENST00000525540.1:n.1574C>T p.X525_splice ENST00000525540 0 +FOXA3 UCSF GRCh37 19 46375379 46375379 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 31 57 0 ENST00000302177.2:c.116C>T p.Ser39Phe p.S39F ENST00000302177 NM_004497.2 39 tCc/tTc 0 +FOXD4 UCSF GRCh37 9 116871 116871 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 31 38 0 ENST00000382500.2:c.1249G>A p.Glu417Lys p.E417K ENST00000382500 NM_207305.4 417 Gag/Aag 0 +FOXF1 UCSF GRCh37 16 86544368 86544368 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 136 55 35 0 ENST00000262426.4:c.193C>T p.Pro65Ser p.P65S ENST00000262426 NM_001451.2 65 Ccc/Tcc 0 +FOXM1 UCSF GRCh37 12 2981341 2981341 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 120 85 140 0 ENST00000359843.3:c.575C>T p.Ser192Phe p.S192F ENST00000359843 NM_021953.3 192 tCt/tTt 0 +FOXR1 UCSF GRCh37 11 118851225 118851225 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 38 71 0 ENST00000317011.3:c.637G>A p.Ala213Thr p.A213T ENST00000317011 NM_181721.2 213 Gcc/Acc 0 +FOXRED2 UCSF GRCh37 22 36894137 36894137 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 30 25 0 ENST00000216187.6:c.1283C>T p.Pro428Leu p.P428L ENST00000216187 NM_024955.5 428 cCc/cTc 0 +FRAS1 UCSF GRCh37 4 79432566 79432566 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 84 138 0 ENST00000264895.6:c.9919C>T p.Pro3307Ser p.P3307S ENST00000264895 NM_025074.6 3307 Cca/Tca 0 +FRAS1 UCSF GRCh37 4 79229230 79229230 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 69 142 0 ENST00000264895.6:c.1545G>A p.Glu515= p.E515= ENST00000264895 NM_025074.6 515 gaG/gaA 0 +FREM1 UCSF GRCh37 9 14770618 14770618 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 52 74 0 ENST00000380880.3:c.5044G>A p.Glu1682Lys p.E1682K ENST00000380880 1682 Gag/Aag 0 +FREM2 UCSF GRCh37 13 39263675 39263675 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 39 68 0 ENST00000280481.7:c.2194G>A p.Asp732Asn p.D732N ENST00000280481 NM_207361.4 732 Gac/Aac 0 +FRMD3 UCSF GRCh37 9 85863162 85863162 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 58 112 0 ENST00000304195.3:c.1465G>A p.Asp489Asn p.D489N ENST00000304195 NM_001244960.1 489 Gat/Aat 0 +FRMD6 UCSF GRCh37 14 52194727 52194727 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 20 31 0 ENST00000344768.5:c.1849G>A p.Val617Ile p.V617I ENST00000344768 617 Gtt/Att 0 +FRMPD1 UCSF GRCh37 9 37746123 37746123 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 82 72 0 ENST00000377765.3:c.4094C>T p.Pro1365Leu p.P1365L ENST00000377765 NM_014907.2 1365 cCc/cTc 0 +FRMPD1 UCSF GRCh37 9 37735548 37735548 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 36 88 0 ENST00000377765.3:c.1219-1G>A p.X407_splice ENST00000377765 NM_014907.2 0 +FRY UCSF GRCh37 13 32653159 32653159 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 130 80 110 0 ENST00000380250.3:c.259G>A p.Ala87Thr p.A87T ENST00000380250 NM_023037.2 87 Gca/Aca 0 +FRY UCSF GRCh37 13 32805425 32805425 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 63 86 0 ENST00000380250.3:c.5515G>A p.Asp1839Asn p.D1839N ENST00000380250 NM_023037.2 1839 Gat/Aat 0 +FRY UCSF GRCh37 13 32868530 32868530 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 37 64 0 ENST00000542859.1:c.716G>A p.Ser239Asn p.S239N ENST00000542859 239 aGt/aAt 0 +FRY UCSF GRCh37 13 32776558 32776558 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 64 68 0 ENST00000380250.3:c.3912C>T p.Leu1304= p.L1304= ENST00000380250 NM_023037.2 1304 ctC/ctT 0 +FSCB UCSF GRCh37 14 44975886 44975886 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 126 87 201 0 ENST00000340446.4:c.305G>A p.Arg102Lys p.R102K ENST00000340446 NM_032135.3 102 aGa/aAa 0 +FSCB UCSF GRCh37 14 44974999 44974999 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 39 73 0 ENST00000340446.4:c.1192C>T p.Pro398Ser p.P398S ENST00000340446 NM_032135.3 398 Cct/Tct 0 +FSCN3 UCSF GRCh37 7 127240402 127240402 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 15 49 0 ENST00000265825.5:c.1446C>T p.Thr482= p.T482= ENST00000265825 NM_020369.2 482 acC/acT 0 +FSD1 UCSF GRCh37 19 4318408 4318408 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 22 24 0 ENST00000221856.6:c.865G>A p.Glu289Lys p.E289K ENST00000221856 NM_024333.2 289 Gag/Aag 0 +FSIP1 UCSF GRCh37 15 40005681 40005681 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 72 129 0 ENST00000350221.3:c.1152G>A p.Glu384= p.E384= ENST00000350221 NM_152597.4 384 gaG/gaA 0 +FSIP2 UCSF GRCh37 2 186656884 186656884 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 159 100 165 0 ENST00000424728.1:c.5021C>T p.Pro1674Leu p.P1674L ENST00000424728 1674 cCt/cTt 0 +FSIP2 UCSF GRCh37 2 186665992 186665992 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 54 85 0 ENST00000424728.1:c.11959C>T p.Leu3987Phe p.L3987F ENST00000424728 3987 Ctc/Ttc 0 +FSIP2 UCSF GRCh37 2 186657540 186657540 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 40 85 0 ENST00000424728.1:c.5677G>A p.Ala1893Thr p.A1893T ENST00000424728 1893 Gct/Act 0 +FSIP2 UCSF GRCh37 2 186667048 186667048 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 36 78 0 ENST00000424728.1:c.13015G>A p.Val4339Ile p.V4339I ENST00000424728 4339 Gta/Ata 0 +FSTL4 UCSF GRCh37 5 132560877 132560877 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 31 80 0 ENST00000265342.7:c.1277C>T p.Ser426Phe p.S426F ENST00000265342 NM_015082.1 426 tCc/tTc 0 +FUK UCSF GRCh37 16 70497664 70497664 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 10 15 0 ENST00000288078.6:c.221G>A p.Arg74Gln p.R74Q ENST00000288078 NM_145059.2 74 cGg/cAg 0 +FUT2 UCSF GRCh37 19 49206791 49206791 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 66 40 0 ENST00000391876.4:c.578G>A p.Gly193Asp p.G193D ENST00000391876 193 gGc/gAc 0 +FUT6 UCSF GRCh37 19 5832069 5832069 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 46 42 0 ENST00000286955.5:c.510G>A p.Trp170Ter p.W170* ENST00000286955 NM_001040701.1 170 tgG/tgA 0 +FYB UCSF GRCh37 5 39202562 39202562 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 155 81 171 1 ENST00000351578.6:c.501G>A p.Lys167= p.K167= ENST00000351578 NM_199335.3 167 aaG/aaA 0 +FYCO1 UCSF GRCh37 3 46009818 46009818 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 168 45 51 0 ENST00000296137.2:c.1008C>T p.Ala336= p.A336= ENST00000296137 NM_024513.3 336 gcC/gcT 0 +FYCO1 UCSF GRCh37 3 46009686 46009686 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 287 98 172 0 ENST00000296137.2:c.1140T>C p.Asp380= p.D380= ENST00000296137 NM_024513.3 380 gaT/gaC 0 +FZD10 UCSF GRCh37 12 130647932 130647932 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 208 49 50 0 ENST00000229030.4:c.445G>A p.Glu149Lys p.E149K ENST00000229030 149 Gag/Aag 0 +FZD10 UCSF GRCh37 12 130649027 130649027 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 30 46 0 ENST00000229030.4:c.1540G>A p.Val514Met p.V514M ENST00000229030 514 Gtg/Atg 0 +GABBR1 UCSF GRCh37 6 29574681 29574681 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 38 69 0 ENST00000377034.4:c.2210C>T p.Thr737Ile p.T737I ENST00000377034 NM_001470.2 737 aCc/aTc 0 +GABBR2 UCSF GRCh37 9 101235433 101235433 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 20 36 0 ENST00000259455.2:c.994G>A p.Gly332Arg p.G332R ENST00000259455 NM_005458.7 332 Gga/Aga 0 +GABRB1 UCSF GRCh37 4 47034018 47034018 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 139 79 93 0 ENST00000295454.3:c.168C>T p.Phe56= p.F56= ENST00000295454 NM_000812.3 56 ttC/ttT 0 +GAGE2D UCSF GRCh37 X 49208299 49208313 + protein_altering_variant In_Frame_Ins INS CGGCCTAGACCAAGA CGGCCTAGACCAAGA TATTGGCCTAGACCAAGG NOVEL P05_Rec Untested WXS Illumina HiSeq 9 0 ENST00000404720.2:c.28_42delinsTATTGGCCTAGACCAAGG p.Arg10delinsTyrTrp p.R10delinsYW ENST00000404720 NM_001098407.1 10 CGGCCTAGACCAAGA/TATTGGCCTAGACCAAGG 0 +GALNS UCSF GRCh37 16 88889032 88889032 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 16 18 0 ENST00000268695.5:c.1329C>T p.His443= p.H443= ENST00000268695 NM_000512.4 443 caC/caT 0 +GALNTL5 UCSF GRCh37 7 151705015 151705015 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 127 30 100 0 ENST00000392800.2:c.1012G>A p.Glu338Lys p.E338K ENST00000392800 NM_145292.3 338 Gaa/Aaa 0 +GAPVD1 UCSF GRCh37 9 128099780 128099780 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 22 50 0 ENST00000394104.2:c.2787C>T p.Leu929= p.L929= ENST00000394104 NM_001282679.1 929 ctC/ctT 0 +GARNL3 UCSF GRCh37 9 130127616 130127616 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 225 64 123 0 ENST00000373387.4:c.2132G>A p.Gly711Glu p.G711E ENST00000373387 NM_032293.4 711 gGa/gAa 0 +GAS2L2 UCSF GRCh37 17 34072427 34072427 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 71 72 0 ENST00000254466.6:c.2089G>A p.Gly697Arg p.G697R ENST00000254466 NM_139285.3 697 Gga/Aga 0 +GAS2L3 UCSF GRCh37 12 100994246 100994246 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 35 95 0 ENST00000266754.5:c.105C>T p.Tyr35= p.Y35= ENST00000266754 35 taC/taT 0 +GATAD1 UCSF GRCh37 7 92083940 92083940 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 149 49 72 0 ENST00000287957.3:c.560G>A p.Trp187Ter p.W187* ENST00000287957 NM_021167.4 187 tGg/tAg 0 +GCAT UCSF GRCh37 22 38205992 38205992 + intron_variant Intron SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 43 61 0 ENST00000248924.6:c.197-42C>T *66* ENST00000248924 NM_014291.3 0 +GCAT UCSF GRCh37 22 38205980 38205980 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 34 59 0 ENST00000248924.6:c.197-54G>A *66* ENST00000248924 NM_014291.3 0 +GCNT3 UCSF GRCh37 15 59911202 59911202 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.004,1000g2011may_all_0.01089,snp132_rs35655456 P05_Rec Untested WXS Illumina HiSeq 192 90 169 0 ENST00000396065.1:c.765G>A p.Glu255= p.E255= ENST00000396065 NM_004751.2 255 gaG/gaA 0 +GCNT7 UCSF GRCh37 20 55070281 55070281 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 13 40 0 ENST00000243913.4:c.677G>A p.Gly226Glu p.G226E ENST00000243913 NM_080615.1 226 gGa/gAa 0 +GFI1B UCSF GRCh37 9 135862166 135862166 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 8 10 0 ENST00000339463.3:c.100+1G>A p.X34_splice ENST00000339463 0 +GFRA1 UCSF GRCh37 10 117823939 117823939 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 31 52 0 ENST00000355422.6:c.1368C>T p.Ser456= p.S456= ENST00000355422 NM_005264.4 456 tcC/tcT 0 +GGT1 UCSF GRCh37 22 25007180 25007180 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 7 24 1 ENST00000248923.4:c.132C>T p.Ala44= p.A44= ENST00000248923 NM_013430.2 44 gcC/gcT 0 +GHRHR UCSF GRCh37 7 31008476 31008476 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 21 41 0 ENST00000326139.2:c.85G>T p.Asp29Tyr p.D29Y ENST00000326139 NM_000823.3 29 Gac/Tac 0 +GIMAP2 UCSF GRCh37 7 150389551 150389551 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 29 94 0 ENST00000223293.5:c.177G>A p.Lys59= p.K59= ENST00000223293 NM_015660.2 59 aaG/aaA 0 +GIMAP8 UCSF GRCh37 7 150163967 150163967 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 160 69 115 0 ENST00000307271.3:c.181G>A p.Val61Ile p.V61I ENST00000307271 NM_175571.2 61 Gtt/Att 0 +GIMAP8 UCSF GRCh37 7 150171237 150171237 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 119 27 59 0 ENST00000307271.3:c.820C>T p.Gln274Ter p.Q274* ENST00000307271 NM_175571.2 274 Cag/Tag 0 +GIT1 UCSF GRCh37 17 27904199 27904199 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 175 106 89 0 ENST00000225394.3:c.1048G>A p.Glu350Lys p.E350K ENST00000225394 NM_014030.3 350 Gag/Aag 0 +GJB6 UCSF GRCh37 13 20797371 20797371 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 28 35 0 ENST00000241124.6:c.249C>T p.Phe83= p.F83= ENST00000241124 NM_006783.4 83 ttC/ttT 0 +GJB7 UCSF GRCh37 6 87994398 87994398 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 46 90 0 ENST00000296882.3:c.233C>T p.Ala78Val p.A78V ENST00000296882 78 gCc/gTc 0 +GLDC UCSF GRCh37 9 6592855 6592855 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 32 73 0 ENST00000321612.6:c.1397G>A p.Gly466Asp p.G466D ENST00000321612 NM_000170.2 466 gGc/gAc 0 +GLDC UCSF GRCh37 9 6587248 6587248 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 29 68 0 ENST00000321612.6:c.1743C>T p.Pro581= p.P581= ENST00000321612 NM_000170.2 581 ccC/ccT 0 +GLI3 UCSF GRCh37 7 42187981 42187981 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 12 43 0 ENST00000395925.3:c.211G>A p.Val71Ile p.V71I ENST00000395925 NM_000168.5 71 Gtc/Atc 0 +GLI3 UCSF GRCh37 7 42079724 42079724 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 39 54 0 ENST00000395925.3:c.941C>T p.Pro314Leu p.P314L ENST00000395925 NM_000168.5 314 cCc/cTc 0 +GLIS3 UCSF GRCh37 9 3937133 3937133 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 59 72 0 ENST00000324333.10:c.1302G>A p.Arg434= p.R434= ENST00000324333 NM_152629.3 434 cgG/cgA 0 +GLRA4 UCSF GRCh37 X 102977152 102977152 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 122 131 0 ENST00000372617.4:c.646G>A p.Gly216Arg p.G216R ENST00000372617 NM_001024452.2 216 Ggg/Agg 0 +GLT8D2 UCSF GRCh37 12 104387238 104387238 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 9 19 0 ENST00000360814.4:c.812C>T p.Ser271Phe p.S271F ENST00000360814 NM_031302.3 271 tCc/tTc 0 +GLUD1 UCSF GRCh37 10 88818930 88818930 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 99 132 0 ENST00000277865.4:c.1379G>A p.Arg460Lys p.R460K ENST00000277865 NM_005271.3 460 aGg/aAg 0 +GLYAT UCSF GRCh37 11 58491934 58491934 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 50 80 0 ENST00000344743.3:c.36G>A p.Gln12= p.Q12= ENST00000344743 NM_201648.2 12 caG/caA 0 +GMEB1 UCSF GRCh37 1 29041273 29041273 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 35 64 0 ENST00000294409.2:c.1710C>T p.Val570= p.V570= ENST00000294409 NM_006582.3 570 gtC/gtT 0 +GMEB2 UCSF GRCh37 20 62221730 62221730 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 16 8 0 ENST00000266068.1:c.1305C>T p.Ala435= p.A435= ENST00000266068 435 gcC/gcT 0 +GMPR UCSF GRCh37 6 16254852 16254852 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 57 125 1 ENST00000259727.4:c.351G>A p.Leu117= p.L117= ENST00000259727 NM_006877.3 117 ctG/ctA 0 +GNAI1 UCSF GRCh37 7 79818509 79818509 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 19 51 0 ENST00000351004.3:c.265G>A p.Gly89Arg p.G89R ENST00000351004 NM_002069.5 89 Ggg/Agg 0 +GNAI2 UCSF GRCh37 3 50294993 50294993 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 14 46 0 ENST00000313601.6:c.939G>A p.Lys313= p.K313= ENST00000313601 NM_002070.2 313 aaG/aaA 0 +GNG4 UCSF GRCh37 1 235715517 235715517 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 49 88 0 ENST00000366597.1:c.120C>T p.Asp40= p.D40= ENST00000366597 40 gaC/gaT 0 +GNPAT UCSF GRCh37 1 231403448 231403448 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 57 101 0 ENST00000366647.4:c.1078G>A p.Glu360Lys p.E360K ENST00000366647 NM_014236.3 360 Gag/Aag 0 +GON4L UCSF GRCh37 1 155774791 155774791 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 51 118 0 ENST00000368331.1:c.1594G>A p.Asp532Asn p.D532N ENST00000368331 NM_001037533.1 532 Gac/Aac 0 +GORASP1 UCSF GRCh37 3 39141805 39141805 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 20 27 0 ENST00000319283.3:c.756C>T p.Asp252= p.D252= ENST00000319283 NM_031899.3 252 gaC/gaT 0 +GPC3 UCSF GRCh37 X 132888089 132888089 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 92 157 0 ENST00000370818.3:c.452A>T p.Asp151Val p.D151V ENST00000370818 NM_001164618.1 151 gAt/gTt 0 +GPHN UCSF GRCh37 14 67626206 67626206 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 51 60 0 ENST00000315266.5:c.1811+1G>A p.X604_splice ENST00000315266 NM_001024218.1 0 +GPM6B UCSF GRCh37 X 13825868 13825868 + intron_variant Intron SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 45 89 0 ENST00000356942.5:c.61+9095G>A *21* ENST00000356942 NM_005278.3 0 +GPR124 UCSF GRCh37 8 37690588 37690588 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 53 50 0 ENST00000412232.2:c.1158C>T p.Thr386= p.T386= ENST00000412232 NM_032777.9 386 acC/acT 0 +GPR146 UCSF GRCh37 7 1097986 1097986 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 35 55 0 ENST00000297468.3:c.835G>A p.Asp279Asn p.D279N ENST00000297468 NM_138445.2 279 Gat/Aat 0 +GPR155 UCSF GRCh37 2 175335147 175335147 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 17 50 0 ENST00000295500.4:c.997G>A p.Ala333Thr p.A333T ENST00000295500 NM_001033045.3 333 Gca/Aca 0 +GPR179 UCSF GRCh37 17 36483358 36483358 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 53 99 0 ENST00000342292.4:c.6094G>A p.Val2032Met p.V2032M ENST00000342292 NM_001004334.2 2032 Gtg/Atg 0 +GPR179 UCSF GRCh37 17 36499107 36499107 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 42 61 0 ENST00000342292.4:c.566C>T p.Pro189Leu p.P189L ENST00000342292 NM_001004334.2 189 cCt/cTt 0 +GPR20 UCSF GRCh37 8 142367957 142367957 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 21 12 0 ENST00000377741.3:c.67G>A p.Val23Met p.V23M ENST00000377741 NM_005293.2 23 Gtg/Atg 0 +GPR20 UCSF GRCh37 8 142367775 142367775 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 62 28 0 ENST00000377741.3:c.249G>A p.Arg83= p.R83= ENST00000377741 NM_005293.2 83 cgG/cgA 0 +GPR3 UCSF GRCh37 1 27720670 27720670 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 134 81 58 0 ENST00000374024.3:c.368G>A p.Ser123Asn p.S123N ENST00000374024 NM_005281.3 123 aGc/aAc 0 +GPR97 UCSF GRCh37 16 57712211 57712211 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 36 46 0 ENST00000333493.4:c.475C>T p.Pro159Ser p.P159S ENST00000333493 NM_170776.4 159 Cca/Tca 0 +GPR98 UCSF GRCh37 5 90368287 90368287 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 68 129 0 ENST00000405460.2:c.18176C>T p.Ala6059Val p.A6059V ENST00000405460 NM_032119.3 6059 gCt/gTt 0 +GPRC5B UCSF GRCh37 16 19883984 19883984 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 46 28 0 ENST00000300571.2:c.184G>A p.Val62Met p.V62M ENST00000300571 NM_016235.1 62 Gtg/Atg 0 +GRB7 UCSF GRCh37 17 37898594 37898594 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 116 77 102 0 ENST00000309156.4:c.40C>T p.Pro14Ser p.P14S ENST00000309156 NM_005310.3 14 Ccg/Tcg 0 +GRHL3 UCSF GRCh37 1 24658026 24658026 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 49 73 0 ENST00000350501.5:c.128C>T p.Ala43Val p.A43V ENST00000350501 NM_198174.2 43 gCc/gTc 0 +GRID2 UCSF GRCh37 4 94436455 94436455 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 53 72 0 ENST00000282020.4:c.2086C>T p.Leu696= p.L696= ENST00000282020 NM_001510.2 696 Ctg/Ttg 0 +GRIN2A UCSF GRCh37 16 9857804 9857804 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 161 79 146 0 ENST00000330684.3:c.3597G>A p.Pro1199= p.P1199= ENST00000330684 NM_001134407.1 1199 ccG/ccA 0 +GRIN2A UCSF GRCh37 16 10273879 10273879 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 45 27 0 ENST00000330684.3:c.390C>T p.Gly130= p.G130= ENST00000330684 NM_001134407.1 130 ggC/ggT 0 +GRIN3B UCSF GRCh37 19 1005407 1005407 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 66 35 0 ENST00000234389.3:c.1907C>T p.Thr636Met p.T636M ENST00000234389 NM_138690.1 636 aCg/aTg 0 +GRK1 UCSF GRCh37 13 114322040 114322040 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 64 67 0 ENST00000335678.6:c.339G>A p.Gln113= p.Q113= ENST00000335678 NM_002929.2 113 caG/caA 0 +GRM1 UCSF GRCh37 6 146351336 146351336 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 31 65 0 ENST00000282753.1:c.683C>T p.Ser228Phe p.S228F ENST00000282753 NM_001278067.1 228 tCt/tTt 0 +GRM1 UCSF GRCh37 6 146673547 146673547 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 52 105 0 ENST00000282753.1:c.1348C>T p.Leu450= p.L450= ENST00000282753 NM_001278067.1 450 Ctg/Ttg 0 +GRM2 UCSF GRCh37 3 51750123 51750123 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 15 31 0 ENST00000395052.3:c.2334C>T p.Pro778= p.P778= ENST00000395052 NM_000839.3 778 ccC/ccT 0 +GSTA3 UCSF GRCh37 6 52764848 52764848 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 61 149 0 ENST00000211122.3:c.298G>A p.Ala100Thr p.A100T ENST00000211122 NM_000847.4 100 Gca/Aca 0 +GTF2A1L UCSF GRCh37 2 48874040 48874040 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 20 37 64 0 ENST00000394754.1:c.2949C>T p.Leu983= p.L983= ENST00000394754 NM_172311.2 983 ctC/ctT 0 +GTF2H4 UCSF GRCh37 6 30880904 30880904 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 27 23 0 ENST00000259895.4:c.1107G>A p.Arg369= p.R369= ENST00000259895 NM_001517.4 369 agG/agA 0 +GTF2IRD1 UCSF GRCh37 7 73927195 73927195 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 29 30 0 ENST00000265755.3:c.159C>T p.Ala53= p.A53= ENST00000265755 NM_005685.3 53 gcC/gcT 0 +GTF3C1 UCSF GRCh37 16 27506726 27506726 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 15 19 0 ENST00000356183.4:c.2438G>A p.Gly813Glu p.G813E ENST00000356183 NM_001520.3 813 gGg/gAg 0 +GTSE1 UCSF GRCh37 22 46704798 46704798 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 46 46 0 ENST00000454366.1:c.720G>A p.Ala240= p.A240= ENST00000454366 NM_016426.6 240 gcG/gcA 0 +GUCY1A2 UCSF GRCh37 11 106558395 106558395 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 142 105 117 0 ENST00000526355.2:c.2079C>T p.Ile693= p.I693= ENST00000526355 NM_000855.2 693 atC/atT 0 +GUF1 UCSF GRCh37 4 44688578 44688578 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 56 90 0 ENST00000281543.5:c.786C>T p.Thr262= p.T262= ENST00000281543 NM_021927.2 262 acC/acT 0 +GZMH UCSF GRCh37 14 25077492 25077492 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 33 74 0 ENST00000216338.4:c.182C>T p.Thr61Ile p.T61I ENST00000216338 NM_033423.4 61 aCa/aTa 0 +H1FNT UCSF GRCh37 12 48723752 48723752 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 9 13 0 ENST00000335017.1:c.678G>A p.Thr226= p.T226= ENST00000335017 NM_181788.1 226 acG/acA 0 +H6PD UCSF GRCh37 1 9324739 9324739 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 49 17 0 ENST00000377403.2:c.2187G>A p.Met729Ile p.M729I ENST00000377403 NM_004285.3 729 atG/atA 0 +HACE1 UCSF GRCh37 6 105225138 105225138 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 48 73 0 ENST00000262903.4:c.1621G>A p.Asp541Asn p.D541N ENST00000262903 NM_020771.3 541 Gat/Aat 0 +HACE1 UCSF GRCh37 6 105232911 105232911 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 46 86 0 ENST00000262903.4:c.1358G>A p.Ser453Asn p.S453N ENST00000262903 NM_020771.3 453 aGt/aAt 0 +HADHA UCSF GRCh37 2 26415196 26415196 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 66 109 0 ENST00000380649.3:c.1983G>A p.Leu661= p.L661= ENST00000380649 NM_000182.4 661 ctG/ctA 0 +HAO2 UCSF GRCh37 1 119927582 119927582 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 39 90 0 ENST00000325945.3:c.467C>T p.Thr156Ile p.T156I ENST00000325945 NM_016527.2 156 aCt/aTt 0 +HCRTR1 UCSF GRCh37 1 32084911 32084911 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 165 78 70 0 ENST00000373706.5:c.118C>T p.Leu40= p.L40= ENST00000373706 40 Ctg/Ttg 0 +HDAC4 UCSF GRCh37 2 240029877 240029877 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 12 12 0 ENST00000345617.3:c.1966C>T p.Leu656Phe p.L656F ENST00000345617 NM_006037.3 656 Ctc/Ttc 0 +HDAC6 UCSF GRCh37 X 48666703 48666703 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 7 20 0 ENST00000334136.5:c.776G>A p.Gly259Glu p.G259E ENST00000334136 259 gGa/gAa 0 +HDC UCSF GRCh37 15 50535041 50535041 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 39 46 43 0 ENST00000267845.3:c.1405G>C p.Asp469His p.D469H ENST00000267845 NM_002112.3 469 Gat/Cat 0 +HDC UCSF GRCh37 15 50546769 50546769 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 25 46 0 ENST00000267845.3:c.534G>A p.Glu178= p.E178= ENST00000267845 NM_002112.3 178 gaG/gaA 0 +HEATR1 UCSF GRCh37 1 236761195 236761195 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 37 80 0 ENST00000366582.3:c.586G>A p.Val196Met p.V196M ENST00000366582 NM_018072.5 196 Gtg/Atg 0 +HEATR3 UCSF GRCh37 16 50112689 50112689 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 26 51 0 ENST00000299192.7:c.801G>A p.Lys267= p.K267= ENST00000299192 NM_182922.2 267 aaG/aaA 0 +HEATR4 UCSF GRCh37 14 73987712 73987712 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 44 118 0 ENST00000334988.2:c.913G>A p.Val305Ile p.V305I ENST00000334988 NM_203309.2 305 Gtt/Att 0 +HECTD1 UCSF GRCh37 14 31575929 31575929 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 43 62 0 ENST00000399332.1:c.7149G>A p.Glu2383= p.E2383= ENST00000399332 NM_015382.2 2383 gaG/gaA 0 +HELQ UCSF GRCh37 4 84342833 84342833 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 30 43 0 ENST00000295488.3:c.2832G>A p.Leu944= p.L944= ENST00000295488 NM_133636.2 944 ttG/ttA 0 +HEPH UCSF GRCh37 X 65483531 65483531 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 32 85 0 ENST00000343002.2:c.3244+1G>A p.X1082_splice ENST00000343002 0 +HEPHL1 UCSF GRCh37 11 93806331 93806331 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 95 146 0 ENST00000315765.9:c.1372+1G>A p.X458_splice ENST00000315765 NM_001098672.1 0 +HERC2 UCSF GRCh37 15 28408403 28408403 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 48 57 0 ENST00000261609.7:c.10583G>A p.Gly3528Asp p.G3528D ENST00000261609 NM_004667.5 3528 gGt/gAt 0 +HERC2 UCSF GRCh37 15 28517390 28517390 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 15 48 0 ENST00000261609.7:c.1054G>A p.Asp352Asn p.D352N ENST00000261609 NM_004667.5 352 Gat/Aat 0 +HESX1 UCSF GRCh37 3 57232915 57232915 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 254 142 176 0 ENST00000295934.3:c.223G>A p.Val75Met p.V75M ENST00000295934 NM_003865.2 75 Gtg/Atg 0 +HEXDC UCSF GRCh37 17 80395092 80395092 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 141 79 40 0 ENST00000327949.9:c.752C>T p.Ala251Val p.A251V ENST00000327949 251 gCa/gTa 0 +HFM1 UCSF GRCh37 1 91844621 91844621 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 28 47 0 ENST00000370425.3:c.1157C>T p.Pro386Leu p.P386L ENST00000370425 NM_001017975.3 386 cCa/cTa 0 +HIAT1 UCSF GRCh37 1 100535242 100535242 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 36 72 0 ENST00000370152.3:c.891+1G>A p.X297_splice ENST00000370152 NM_033055.2 0 +HIF1A UCSF GRCh37 14 62204870 62204870 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 55 66 0 ENST00000337138.4:c.1315C>T p.Pro439Ser p.P439S ENST00000337138 NM_001530.3 439 Ccc/Tcc 0 +HIP1 UCSF GRCh37 7 75211432 75211432 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 5 13 0 ENST00000336926.6:c.501C>T p.Asp167= p.D167= ENST00000336926 NM_005338.6 167 gaC/gaT 0 +HIST1H2AE UCSF GRCh37 6 26217364 26217364 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 41 81 0 ENST00000303910.2:c.162G>A p.Ala54= p.A54= ENST00000303910 NM_021052.2 54 gcG/gcA 0 +HIST1H4L UCSF GRCh37 6 27841178 27841178 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 68 58 0 ENST00000355981.2:c.111C>T p.Arg37= p.R37= ENST00000355981 NM_003546.2 37 cgC/cgT 0 +HIST3H2BB UCSF GRCh37 1 228645954 228645954 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 203 113 88 0 ENST00000369160.2:c.124G>A p.Val42Met p.V42M ENST00000369160 NM_175055.2 42 Gtg/Atg 0 +HIVEP1 UCSF GRCh37 6 12164042 12164042 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 51 83 0 ENST00000379388.2:c.7505C>T p.Ala2502Val p.A2502V ENST00000379388 NM_002114.2 2502 gCc/gTc 0 +HK3 UCSF GRCh37 5 176315739 176315739 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 33 49 0 ENST00000292432.5:c.1041C>T p.Ile347= p.I347= ENST00000292432 NM_002115.2 347 atC/atT 0 +HKR1 UCSF GRCh37 19 37854105 37854105 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 41 92 0 ENST00000324411.4:c.1408G>A p.Val470Ile p.V470I ENST00000324411 NM_181786.2 470 Gtc/Atc 0 +HLA-DPB1 UCSF GRCh37 6 33053574 33053574 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 19 56 0 ENST00000418931.2:c.665C>T p.Ala222Val p.A222V ENST00000418931 NM_002121.5 222 gCc/gTc 0 +HLA-F UCSF GRCh37 6 29692880 29692880 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 61 34 62 0 ENST00000334668.4:c.683G>C p.Gly228Ala p.G228A ENST00000334668 NM_018950.2 228 gGc/gCc 0 +HMCN1 UCSF GRCh37 1 186039866 186039866 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 42 97 0 ENST00000271588.4:c.8116C>T p.Leu2706Phe p.L2706F ENST00000271588 NM_031935.2 2706 Ctc/Ttc 0 +HMCN1 UCSF GRCh37 1 186007969 186007969 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 68 47 83 0 ENST00000271588.4:c.5860T>C p.Trp1954Arg p.W1954R ENST00000271588 NM_031935.2 1954 Tgg/Cgg 0 +HMG20A UCSF GRCh37 15 77771634 77771634 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 29 86 0 ENST00000336216.4:c.1021G>A p.Val341Ile p.V341I ENST00000336216 341 Gtt/Att 0 +HMGXB4 UCSF GRCh37 22 35659100 35659100 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 26 54 0 ENST00000216106.5:c.61G>A p.Asp21Asn p.D21N ENST00000216106 NM_001003681.2 21 Gac/Aac 0 +HMGXB4 UCSF GRCh37 22 35659836 35659836 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 20 61 0 ENST00000216106.5:c.228G>A p.Arg76= p.R76= ENST00000216106 NM_001003681.2 76 agG/agA 0 +HNRNPH2 UCSF GRCh37 X 100668241 100668241 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 139 166 0 ENST00000316594.5:c.1265G>A p.Gly422Asp p.G422D ENST00000316594 NM_001199974.1 422 gGt/gAt 0 +HNRNPU UCSF GRCh37 1 245021367 245021367 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 49 73 0 ENST00000283179.9:c.1440C>T p.Pro480= p.P480= ENST00000283179 480 ccC/ccT 0 +HOOK3 UCSF GRCh37 8 42868530 42868530 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 48 51 0 ENST00000307602.4:c.2003C>T p.Ala668Val p.A668V ENST00000307602 NM_032410.3 668 gCc/gTc 0 +HOXB3 UCSF GRCh37 17 46628137 46628137 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 150 70 50 0 ENST00000311626.4:c.855C>T p.Ser285= p.S285= ENST00000311626 NM_002146.4 285 agC/agT 0 +HOXD4 UCSF GRCh37 2 177017514 177017514 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 178 83 84 0 ENST00000306324.3:c.612C>T p.Asn204= p.N204= ENST00000306324 NM_014621.2 204 aaC/aaT 0 +HPN UCSF GRCh37 19 35556929 35556929 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 119 51 63 0 ENST00000262626.2:c.1208C>T p.Ala403Val p.A403V ENST00000262626 NM_182983.2 403 gCc/gTc 0 +HPS1 UCSF GRCh37 10 100183425 100183425 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 85 82 0 ENST00000325103.6:c.1533G>A p.Arg511= p.R511= ENST00000325103 NM_000195.3 511 cgG/cgA 0 +HRC UCSF GRCh37 19 49657604 49657604 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 33 33 0 ENST00000252825.4:c.891C>T p.His297= p.H297= ENST00000252825 NM_002152.2 297 caC/caT 0 +HRH2 UCSF GRCh37 5 175110320 175110320 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 81 149 0 ENST00000231683.2:c.84C>T p.Leu28= p.L28= ENST00000231683 NM_022304.2 28 ctC/ctT 0 +HSD17B13 UCSF GRCh37 4 88231402 88231402 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 29 47 0 ENST00000328546.4:c.805C>T p.Leu269= p.L269= ENST00000328546 NM_178135.3 269 Cta/Tta 0 +HSF4 UCSF GRCh37 16 67199654 67199654 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 31 12 0 ENST00000264009.8:c.265G>A p.Gly89Ser p.G89S ENST00000264009 NM_001040667.2 89 Ggc/Agc 0 +HSPA5 UCSF GRCh37 9 127999235 127999235 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 130 63 154 0 ENST00000324460.6:c.1601C>T p.Thr534Ile p.T534I ENST00000324460 NM_005347.4 534 aCa/aTa 0 +HSPB1 UCSF GRCh37 7 75933374 75933374 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 11 13 0 ENST00000248553.6:c.502C>T p.Pro168Ser p.P168S ENST00000248553 NM_001540.3 168 Ccc/Tcc 0 +HSPBAP1 UCSF GRCh37 3 122459251 122459251 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 32 82 0 ENST00000306103.2:c.1408G>A p.Val470Met p.V470M ENST00000306103 NM_024610.5 470 Gtg/Atg 0 +HSPBP1 UCSF GRCh37 19 55790887 55790888 + inframe_insertion In_Frame_Ins INS - - GCCGCCGCC snp132_rs71743637 P05_Rec Untested WXS Illumina HiSeq 8 0 ENST00000255631.5:c.89_90insGGCGGCGGC p.Gly30_Ser31insAlaAlaAla p.G30_S31insAAA ENST00000255631 NM_012267.4 30 ggc/ggGGCGGCGGCc 0 +HSPG2 UCSF GRCh37 1 22150810 22150810 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 55 38 0 ENST00000374695.3:c.12804C>T p.His4268= p.H4268= ENST00000374695 NM_005529.5 4268 caC/caT 0 +HSPG2 UCSF GRCh37 1 22222744 22222744 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 135 74 114 0 ENST00000374695.3:c.123C>T p.Val41= p.V41= ENST00000374695 NM_005529.5 41 gtC/gtT 0 +HTR1B UCSF GRCh37 6 78172409 78172409 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 37 67 0 ENST00000369947.2:c.712C>T p.Arg238Trp p.R238W ENST00000369947 NM_000863.1 238 Cgg/Tgg 0 +HTR7 UCSF GRCh37 10 92503445 92503445 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 36 72 0 ENST00000336152.3:c.1298G>A p.Arg433Lys p.R433K ENST00000336152 NM_019859.3 433 aGg/aAg 0 +HTT UCSF GRCh37 4 3215750 3215750 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 27 29 0 ENST00000355072.5:c.6840C>T p.Asp2280= p.D2280= ENST00000355072 NM_002111.6 2280 gaC/gaT 0 +HVCN1 UCSF GRCh37 12 111099232 111099232 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 34 40 0 ENST00000242607.8:c.43G>A p.Val15Met p.V15M ENST00000242607 NM_032369.3 15 Gtg/Atg 0 +HVCN1 UCSF GRCh37 12 111099099 111099099 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 18 44 0 ENST00000242607.8:c.176C>T p.Pro59Leu p.P59L ENST00000242607 NM_032369.3 59 cCc/cTc 0 +HYDIN UCSF GRCh37 16 70867797 70867797 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 6 27 0 ENST00000393567.2:c.13672G>A p.Gly4558Ser p.G4558S ENST00000393567 NM_001270974.1 4558 Ggt/Agt 0 +HYDIN UCSF GRCh37 16 70871667 70871667 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 22 90 0 ENST00000393567.2:c.13168G>A p.Glu4390Lys p.E4390K ENST00000393567 NM_001270974.1 4390 Gaa/Aaa 0 +HYDIN UCSF GRCh37 16 70996005 70996005 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 141 24 122 0 ENST00000393567.2:c.5825C>T p.Ser1942Phe p.S1942F ENST00000393567 NM_001270974.1 1942 tCc/tTc 0 +HYDIN UCSF GRCh37 16 70972528 70972528 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 234 64 91 0 ENST00000393567.2:c.6984G>A p.Glu2328= p.E2328= ENST00000393567 NM_001270974.1 2328 gaG/gaA 0 +HYOU1 UCSF GRCh37 11 118922844 118922844 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 49 52 0 ENST00000404233.3:c.1163G>A p.Arg388Gln p.R388Q ENST00000404233 NM_001130991.1 388 cGg/cAg 0 +IBTK UCSF GRCh37 6 82912255 82912255 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 145 92 100 0 ENST00000306270.7:c.2719C>T p.Leu907Phe p.L907F ENST00000306270 NM_015525.2 907 Ctt/Ttt 0 +ICAM4 UCSF GRCh37 19 10398503 10398503 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 64 51 0 ENST00000380770.3:c.686C>T p.Thr229Ile p.T229I ENST00000380770 NM_001544.4 229 aCa/aTa 0 +ICAM5 UCSF GRCh37 19 10402332 10402332 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 110 61 41 0 ENST00000221980.4:c.520C>T p.Pro174Ser p.P174S ENST00000221980 NM_003259.3 174 Ccc/Tcc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 26 75 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IDH3A UCSF GRCh37 15 78452452 78452452 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 55 70 0 ENST00000299518.2:c.193G>A p.Glu65Lys p.E65K ENST00000299518 NM_005530.2 65 Gag/Aag 0 +IFI44L UCSF GRCh37 1 79107151 79107151 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 43 49 0 ENST00000370751.5:c.1181C>T p.Pro394Leu p.P394L ENST00000370751 NM_006820.2 394 cCt/cTt 0 +IFIT1 UCSF GRCh37 10 91163308 91163308 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 39 73 0 ENST00000371804.3:c.1276G>A p.Val426Ile p.V426I ENST00000371804 NM_001270927.1 426 Gtt/Att 0 +IFRD2 UCSF GRCh37 3 50327620 50327620 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 54 44 0 ENST00000417626.2:c.369G>A p.Leu123= p.L123= ENST00000417626 NM_006764.4 123 ctG/ctA 0 +IFT122 UCSF GRCh37 3 129234339 129234339 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 29 34 0 ENST00000348417.2:c.3162G>A p.Val1054= p.V1054= ENST00000348417 NM_052989.2 1054 gtG/gtA 0 +IFT81 UCSF GRCh37 12 110600794 110600794 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 33 81 0 ENST00000242591.5:c.1112G>A p.Ser371Asn p.S371N ENST00000242591 NM_014055.3 371 aGc/aAc 0 +IGFBPL1 UCSF GRCh37 9 38411424 38411424 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 32 59 0 ENST00000377694.1:c.810C>T p.His270= p.H270= ENST00000377694 NM_001007563.2 270 caC/caT 0 +IGFN1 UCSF GRCh37 1 201190766 201190766 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 17 20 0 ENST00000295591.8:c.1573G>A p.Gly525Arg p.G525R ENST00000295591 525 Ggg/Agg 0 +IGFN1 UCSF GRCh37 1 201183324 201183324 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 17 31 0 ENST00000295591.8:c.228C>T p.Ser76= p.S76= ENST00000295591 76 tcC/tcT 0 +IGSF3 UCSF GRCh37 1 117150657 117150657 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 48 159 0 ENST00000369486.3:c.1129C>T p.Arg377Trp p.R377W ENST00000369486 NM_001007237.2 377 Cgg/Tgg 0 +IGSF9 UCSF GRCh37 1 159898250 159898250 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 13 6 9 0 ENST00000368094.1:c.2928C>T p.Ser976= p.S976= ENST00000368094 NM_001135050.1 976 tcC/tcT 0 +IKBIP UCSF GRCh37 12 99007524 99007524 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 55 94 0 ENST00000342502.2:c.892G>A p.Val298Ile p.V298I ENST00000342502 NM_201612.2 298 Gta/Ata 0 +IL17RD UCSF GRCh37 3 57131798 57131798 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 143 39 36 0 ENST00000296318.7:c.1933C>T p.Pro645Ser p.P645S ENST00000296318 NM_017563.3 645 Ccc/Tcc 0 +IL17RD UCSF GRCh37 3 57140020 57140020 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 151 39 89 0 ENST00000296318.7:c.612C>T p.Asn204= p.N204= ENST00000296318 NM_017563.3 204 aaC/aaT 0 +IL1F10 UCSF GRCh37 2 113832830 113832830 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 50 58 0 ENST00000341010.2:c.348C>T p.Ala116= p.A116= ENST00000341010 NM_173161.2 116 gcC/gcT 0 +IL1R2 UCSF GRCh37 2 102642637 102642637 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 44 88 0 ENST00000332549.3:c.952G>A p.Glu318Lys p.E318K ENST00000332549 NM_004633.3 318 Gag/Aag 0 +IL1RL1 UCSF GRCh37 2 102968206 102968206 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 33 59 0 ENST00000233954.1:c.1496C>T p.Ser499Phe p.S499F ENST00000233954 NM_016232.4 499 tCc/tTc 0 +IL27RA UCSF GRCh37 19 14160068 14160068 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 22 43 0 ENST00000263379.2:c.1344C>T p.His448= p.H448= ENST00000263379 NM_004843.3 448 caC/caT 0 +IL27RA UCSF GRCh37 19 14162973 14162973 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 4 10 0 ENST00000263379.2:c.1782G>A p.Pro594= p.P594= ENST00000263379 NM_004843.3 594 ccG/ccA 0 +ILVBL UCSF GRCh37 19 15234266 15234266 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 68 55 31 0 ENST00000263383.3:c.257A>C p.Glu86Ala p.E86A ENST00000263383 NM_006844.4 86 gAg/gCg 0 +IMPA1 UCSF GRCh37 8 82583203 82583203 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 15 24 0 ENST00000256108.5:c.537G>A p.Met179Ile p.M179I ENST00000256108 NM_005536.3 179 atG/atA 0 +IMPDH1 UCSF GRCh37 7 128040521 128040521 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 14 12 0 ENST00000470772.1:c.394G>A p.Ala132Thr p.A132T ENST00000470772 NM_001142573.1 132 Gcc/Acc 0 +IMPDH2 UCSF GRCh37 3 49065942 49065942 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 18 37 0 ENST00000326739.4:c.171G>A p.Lys57= p.K57= ENST00000326739 NM_000884.2 57 aaG/aaA 0 +INO80 UCSF GRCh37 15 41313250 41313250 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 50 57 0 ENST00000361937.3:c.3122G>A p.Gly1041Glu p.G1041E ENST00000361937 1041 gGa/gAa 0 +INPP4B UCSF GRCh37 4 143033752 143033752 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 75 56 92 0 ENST00000262992.4:c.2219A>G p.His740Arg p.H740R ENST00000262992 NM_001101669.1 740 cAt/cGt 0 +INPP5F UCSF GRCh37 10 121582651 121582651 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 12 22 36 0 ENST00000361976.2:c.2101G>A p.Ala701Thr p.A701T ENST00000361976 NM_014937.3 701 Gcg/Acg 0 +INPPL1 UCSF GRCh37 11 71940181 71940181 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 37 26 0 ENST00000298229.2:c.566G>A p.Ser189Asn p.S189N ENST00000298229 NM_001567.3 189 aGc/aAc 0 +INSRR UCSF GRCh37 1 156823907 156823907 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 35 26 0 ENST00000368195.3:c.274G>A p.Glu92Lys p.E92K ENST00000368195 NM_014215.2 92 Gag/Aag 0 +INSRR UCSF GRCh37 1 156815549 156815549 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 25 11 0 ENST00000368195.3:c.2036C>T p.Pro679Leu p.P679L ENST00000368195 NM_014215.2 679 cCt/cTt 0 +INTS1 UCSF GRCh37 7 1511251 1511251 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 59 76 0 ENST00000404767.3:c.6211G>A p.Asp2071Asn p.D2071N ENST00000404767 NM_001080453.2 2071 Gac/Aac 0 +INTS1 UCSF GRCh37 7 1516226 1516226 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 17 30 0 ENST00000404767.3:c.5131C>T p.Arg1711Trp p.R1711W ENST00000404767 NM_001080453.2 1711 Cgg/Tgg 0 +INTS5 UCSF GRCh37 11 62415154 62415154 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 131 64 41 0 ENST00000330574.2:c.2398G>A p.Gly800Arg p.G800R ENST00000330574 NM_030628.1 800 Ggg/Agg 0 +IQCC UCSF GRCh37 1 32673044 32673044 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 27 43 0 ENST00000291358.6:c.762C>T p.Pro254= p.P254= ENST00000291358 NM_018134.2 254 ccC/ccT 0 +IQCH UCSF GRCh37 15 67692463 67692463 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 28 48 0 ENST00000335894.4:c.1917G>A p.Gln639= p.Q639= ENST00000335894 NM_001031715.2 639 caG/caA 0 +IRAK1BP1 UCSF GRCh37 6 79607818 79607818 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 39 83 0 ENST00000369940.2:c.550C>T p.Arg184Cys p.R184C ENST00000369940 NM_001010844.3 184 Cgc/Tgc 0 +IRF9 UCSF GRCh37 14 24632661 24632661 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 81 135 0 ENST00000396864.3:c.439G>A p.Asp147Asn p.D147N ENST00000396864 NM_006084.4 147 Gat/Aat 0 +IRGC UCSF GRCh37 19 44222793 44222793 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 48 37 0 ENST00000244314.5:c.83G>A p.Arg28His p.R28H ENST00000244314 NM_019612.3 28 cGc/cAc 0 +IRS1 UCSF GRCh37 2 227663066 227663066 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 59 28 0 ENST00000305123.5:c.389G>A p.Gly130Glu p.G130E ENST00000305123 NM_005544.2 130 gGa/gAa 0 +IRS4 UCSF GRCh37 X 107977851 107977851 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 93 92 0 ENST00000372129.2:c.1724G>A p.Gly575Glu p.G575E ENST00000372129 NM_003604.2 575 gGa/gAa 0 +IRX5 UCSF GRCh37 16 54965234 54965234 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 13 14 0 ENST00000394636.4:c.124G>A p.Gly42Ser p.G42S ENST00000394636 42 Ggc/Agc 0 +ISX UCSF GRCh37 22 35463225 35463225 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.031,1000g2011may_all_0.06778,snp132_rs61739193 P05_Rec Untested WXS Illumina HiSeq 14 6 11 0 ENST00000308700.6:c.145C>T p.Pro49Ser p.P49S ENST00000308700 NM_001008494.1 49 Cca/Tca 0 +ITGA11 UCSF GRCh37 15 68654023 68654023 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 29 68 0 ENST00000315757.7:c.377C>T p.Ser126Phe p.S126F ENST00000315757 NM_001004439.1 126 tCt/tTt 0 +ITGA2 UCSF GRCh37 5 52361693 52361693 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 32 73 0 ENST00000296585.5:c.1829C>T p.Ala610Val p.A610V ENST00000296585 NM_002203.3 610 gCc/gTc 0 +ITGA3 UCSF GRCh37 17 48156278 48156278 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 45 66 0 ENST00000320031.8:c.2388G>A p.Lys796= p.K796= ENST00000320031 NM_002204.2 796 aaG/aaA 0 +ITGA7 UCSF GRCh37 12 56086663 56086663 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 6 22 0 ENST00000555728.1:c.2941G>A p.Val981Met p.V981M ENST00000555728 981 Gtg/Atg 0 +ITGAE UCSF GRCh37 17 3662819 3662819 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 21 79 0 ENST00000263087.4:c.743G>A p.Gly248Glu p.G248E ENST00000263087 NM_002208.4 248 gGa/gAa 0 +ITGAM UCSF GRCh37 16 31341204 31341204 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 27 39 0 ENST00000287497.8:c.2954G>A p.Arg985His p.R985H ENST00000287497 985 cGc/cAc 0 +ITGAX UCSF GRCh37 16 31392317 31392317 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 24 26 0 ENST00000268296.4:c.3376G>A p.Val1126Ile p.V1126I ENST00000268296 NM_000887.3 1126 Gta/Ata 0 +ITPR2 UCSF GRCh37 12 26493114 26493114 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 28 59 0 ENST00000381340.3:c.8005G>A p.Glu2669Lys p.E2669K ENST00000381340 NM_002223.2 2669 Gag/Aag 0 +ITPR3 UCSF GRCh37 6 33661398 33661398 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 36 30 0 ENST00000374316.5:c.7701C>T p.Asn2567= p.N2567= ENST00000374316 2567 aaC/aaT 0 +ITSN1 UCSF GRCh37 21 35153812 35153812 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 28 43 0 ENST00000381318.3:c.1644C>T p.Leu548= p.L548= ENST00000381318 NM_003024.2 548 ctC/ctT 0 +JAG1 UCSF GRCh37 20 10622514 10622514 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 135 70 105 0 ENST00000254958.5:c.2599G>A p.Gly867Arg p.G867R ENST00000254958 NM_000214.2 867 Ggg/Agg 0 +JAG2 UCSF GRCh37 14 105609353 105609353 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 3 13 0 ENST00000331782.3:c.3396C>T p.Asn1132= p.N1132= ENST00000331782 NM_002226.4 1132 aaC/aaT 0 +JAZF1 UCSF GRCh37 7 27880336 27880336 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 273 67 102 0 ENST00000283928.5:c.536G>A p.Gly179Glu p.G179E ENST00000283928 NM_175061.3 179 gGa/gAa 0 +JHDM1D UCSF GRCh37 7 139798772 139798772 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 34 62 0 ENST00000397560.2:c.1825G>A p.Asp609Asn p.D609N ENST00000397560 NM_030647.1 609 Gat/Aat 0 +JUP UCSF GRCh37 17 39919560 39919560 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 30 19 0 ENST00000310706.5:c.1172G>A p.Ser391Asn p.S391N ENST00000310706 NM_021991.2 391 aGt/aAt 0 +KANK4 UCSF GRCh37 1 62740403 62740403 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 30 43 0 ENST00000371153.4:c.373G>A p.Val125Met p.V125M ENST00000371153 NM_181712.4 125 Gtg/Atg 0 +KBTBD8 UCSF GRCh37 3 67054544 67054544 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 56 147 0 ENST00000417314.2:c.1153C>T p.Leu385Phe p.L385F ENST00000417314 385 Ctt/Ttt 0 +KCMF1 UCSF GRCh37 2 85276656 85276656 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 135 92 104 0 ENST00000409785.4:c.769C>T p.Arg257Cys p.R257C ENST00000409785 NM_020122.4 257 Cgt/Tgt 0 +KCMF1 UCSF GRCh37 2 85270743 85270743 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 36 58 0 ENST00000409785.4:c.381C>T p.Asp127= p.D127= ENST00000409785 NM_020122.4 127 gaC/gaT 0 +KCND3 UCSF GRCh37 1 112525199 112525199 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 72 27 0 ENST00000315987.2:c.150G>A p.Arg50= p.R50= ENST00000315987 NM_004980.4 50 agG/agA 0 +KCNG4 UCSF GRCh37 16 84270739 84270739 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 140 49 30 0 ENST00000308251.4:c.353G>A p.Ser118Asn p.S118N ENST00000308251 NM_172347.2 118 aGc/aAc 0 +KCNH8 UCSF GRCh37 3 19492678 19492678 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 135 58 132 0 ENST00000328405.2:c.1607C>T p.Ser536Phe p.S536F ENST00000328405 NM_144633.2 536 tCt/tTt 0 +KCNK2 UCSF GRCh37 1 215298076 215298076 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 67 152 0 ENST00000444842.2:c.458C>T p.Thr153Ile p.T153I ENST00000444842 NM_014217.3 153 aCt/aTt 0 +KCNQ2 UCSF GRCh37 20 62073779 62073779 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 238 126 156 0 ENST00000359125.2:c.796G>A p.Asp266Asn p.D266N ENST00000359125 NM_172107.2 266 Gat/Aat 0 +KCNQ2 UCSF GRCh37 20 62046413 62046413 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 35 24 0 ENST00000359125.2:c.1368G>A p.Gly456= p.G456= ENST00000359125 NM_172107.2 456 ggG/ggA 0 +KCNT1 UCSF GRCh37 9 138656883 138656883 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 21 25 0 ENST00000488444.2:c.985G>A p.Glu329Lys p.E329K ENST00000488444 329 Gag/Aag 0 +KCTD19 UCSF GRCh37 16 67325605 67325605 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 23 33 0 ENST00000304372.5:c.2354C>T p.Thr785Ile p.T785I ENST00000304372 NM_001100915.1 785 aCc/aTc 0 +KCTD20 UCSF GRCh37 6 36454777 36454777 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 165 94 146 0 ENST00000373731.2:c.1085G>A p.Ser362Asn p.S362N ENST00000373731 NM_173562.3 362 aGt/aAt 0 +KCTD6 UCSF GRCh37 3 58487273 58487273 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 19 46 0 ENST00000355076.6:c.628G>A p.Val210Met p.V210M ENST00000355076 NM_153331.3 210 Gtg/Atg 0 +KDR UCSF GRCh37 4 55955592 55955592 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 18 26 0 ENST00000263923.4:c.3353G>A p.Arg1118Gln p.R1118Q ENST00000263923 NM_002253.2 1118 cGa/cAa 0 +KEL UCSF GRCh37 7 142641460 142641460 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 32 55 0 ENST00000355265.2:c.1441G>A p.Ala481Thr p.A481T ENST00000355265 NM_000420.2 481 Gct/Act 0 +KIAA0020 UCSF GRCh37 9 2804383 2804383 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 33 69 0 ENST00000397885.2:c.1895C>A p.Thr632Asn p.T632N ENST00000397885 NM_014878.4 632 aCc/aAc 0 +KIAA0182 UCSF GRCh37 16 85699735 85699735 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 38 52 0 ENST00000253458.7:c.2912G>A p.Gly971Glu p.G971E ENST00000253458 NM_014615.3 971 gGg/gAg 0 +KIAA0319L UCSF GRCh37 1 35972342 35972342 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 55 108 0 ENST00000325722.3:c.537G>A p.Gln179= p.Q179= ENST00000325722 NM_024874.4 179 caG/caA 0 +KIAA0430 UCSF GRCh37 16 15709764 15709764 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 45 78 0 ENST00000396368.3:c.3176G>A p.Gly1059Asp p.G1059D ENST00000396368 NM_001184998.1 1059 gGt/gAt 0 +KIAA0430 UCSF GRCh37 16 15715650 15715650 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 30 37 0 ENST00000396368.3:c.2579G>A p.Ser860Asn p.S860N ENST00000396368 NM_001184998.1 860 aGc/aAc 0 +KIAA0494 UCSF GRCh37 1 47173724 47173724 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 35 43 0 ENST00000371933.3:c.335-1G>A p.X112_splice ENST00000371933 NM_014774.2 0 +KIAA0754 UCSF GRCh37 1 39878149 39878149 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 55 90 0 ENST00000530275.1:c.1804C>T p.His602Tyr p.H602Y ENST00000530275 NM_015038.1 602 Cat/Tat 0 +KIAA0754 UCSF GRCh37 1 39879913 39879913 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 27 21 0 ENST00000530275.1:c.3568G>A p.Val1190Met p.V1190M ENST00000530275 NM_015038.1 1190 Gtg/Atg 0 +KIAA1009 UCSF GRCh37 6 84862522 84862522 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 220 141 232 0 ENST00000403245.3:c.3371C>T p.Ser1124Leu p.S1124L ENST00000403245 NM_014895.2 1124 tCa/tTa 0 +KIAA1024 UCSF GRCh37 15 79749460 79749460 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 142 90 157 0 ENST00000305428.3:c.971G>A p.Arg324Lys p.R324K ENST00000305428 NM_015206.2 324 aGg/aAg 0 +KIAA1024 UCSF GRCh37 15 79760642 79760642 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 17 34 0 ENST00000305428.3:c.2667C>T p.Val889= p.V889= ENST00000305428 NM_015206.2 889 gtC/gtT 0 +KIAA1033 UCSF GRCh37 12 105534999 105534999 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 56 91 0 ENST00000332180.5:c.1762G>A p.Asp588Asn p.D588N ENST00000332180 NM_015275.1 588 Gat/Aat 0 +KIAA1109 UCSF GRCh37 4 123268748 123268748 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 47 57 0 ENST00000264501.4:c.12943G>A p.Ala4315Thr p.A4315T ENST00000264501 4315 Gct/Act 0 +KIAA1147 UCSF GRCh37 7 141386458 141386458 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 34 68 0 ENST00000536163.1:c.269G>A p.Gly90Glu p.G90E ENST00000536163 NM_001080392.1 90 gGa/gAa 0 +KIAA1239 UCSF GRCh37 4 37440874 37440874 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 72 162 0 ENST00000309447.5:c.1158C>T p.Phe386= p.F386= ENST00000309447 NM_001144990.1 386 ttC/ttT 0 +KIAA1267 UCSF GRCh37 17 44249494 44249494 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 36 26 0 ENST00000574590.1:c.16C>T p.Pro6Ser p.P6S ENST00000574590 NM_001193465.1 6 Ccc/Tcc 0 +KIAA1279 UCSF GRCh37 10 70748592 70748592 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 62 37 0 ENST00000361983.4:c.4G>A p.Ala2Thr p.A2T ENST00000361983 NM_015634.3 2 Gcg/Acg 0 +KIAA1407 UCSF GRCh37 3 113729717 113729717 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 74 105 0 ENST00000295878.3:c.1315G>A p.Ala439Thr p.A439T ENST00000295878 NM_020817.1 439 Gca/Aca 0 +KIAA1462 UCSF GRCh37 10 30316188 30316188 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 148 58 77 0 ENST00000375377.1:c.2889C>T p.Asn963= p.N963= ENST00000375377 NM_020848.2 963 aaC/aaT 0 +KIAA1530 UCSF GRCh37 4 1348558 1348558 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 19 23 0 ENST00000389851.4:c.970G>A p.Ala324Thr p.A324T ENST00000389851 NM_020894.2 324 Gct/Act 0 +KIAA1549 UCSF GRCh37 7 138595914 138595914 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 133 27 106 0 ENST00000422774.1:c.3123G>A p.Glu1041= p.E1041= ENST00000422774 1041 gaG/gaA 0 +KIAA1671 UCSF GRCh37 22 25577768 25577768 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 26 19 0 ENST00000358431.3:c.5177G>A p.Gly1726Asp p.G1726D ENST00000358431 NM_001145206.1 1726 gGc/gAc 0 +KIAA1683 UCSF GRCh37 19 18377383 18377383 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 56 76 0 ENST00000600328.3:c.967C>T p.Pro323Ser p.P323S ENST00000600328 323 Ccc/Tcc 0 +KIAA1751 UCSF GRCh37 1 1905497 1905497 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 17 11 0 ENST00000270720.7:n.797G>A *266* ENST00000270720 0 +KIAA1751 UCSF GRCh37 1 1900103 1900104 + non_coding_transcript_exon_variant RNA INS - - TCT NOVEL P05_Rec Untested WXS Illumina HiSeq 6 0 ENST00000270720.7:n.1372_1373insGAA *458* ENST00000270720 0 +KIAA1804 UCSF GRCh37 1 233511670 233511670 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 21 46 0 ENST00000366624.3:c.1684G>A p.Asp562Asn p.D562N ENST00000366624 NM_032435.2 562 Gat/Aat 0 +KIAA2018 UCSF GRCh37 3 113377353 113377353 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 143 48 161 0 ENST00000316407.4:c.3176G>A p.Arg1059Lys p.R1059K ENST00000316407 NM_001009899.2 1059 aGa/aAa 0 +KIAA2018 UCSF GRCh37 3 113377515 113377515 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 60 137 0 ENST00000316407.4:c.3014C>T p.Thr1005Ile p.T1005I ENST00000316407 NM_001009899.2 1005 aCt/aTt 0 +KIAA2022 UCSF GRCh37 X 73962030 73962030 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 123 70 140 0 ENST00000055682.6:c.2362C>T p.Leu788= p.L788= ENST00000055682 NM_001008537.2 788 Cta/Tta 0 +KIF18B UCSF GRCh37 17 43009482 43009482 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 20 48 0 ENST00000593135.1:c.1331G>A p.Gly444Glu p.G444E ENST00000593135 NM_001265577.1 444 gGg/gAg 0 +KIF1B UCSF GRCh37 1 10386370 10386370 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 54 59 0 ENST00000377086.1:c.2877G>A p.Gly959= p.G959= ENST00000377086 959 ggG/ggA 0 +KIF21B UCSF GRCh37 1 200945916 200945916 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 18 16 0 ENST00000422435.2:c.4431C>T p.Asp1477= p.D1477= ENST00000422435 NM_001252100.1 1477 gaC/gaT 0 +KIF23 UCSF GRCh37 15 69728990 69728990 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 40 41 0 ENST00000260363.4:c.1484C>T p.Pro495Leu p.P495L ENST00000260363 NM_138555.3 495 cCa/cTa 0 +KIF24 UCSF GRCh37 9 34256456 34256456 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 121 73 87 0 ENST00000379166.2:c.3149C>T p.Ser1050Phe p.S1050F ENST00000379166 NM_194313.2 1050 tCt/tTt 0 +KIF26A UCSF GRCh37 14 104641411 104641411 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 13 9 0 ENST00000423312.2:c.2286G>A p.Val762= p.V762= ENST00000423312 NM_015656.1 762 gtG/gtA 0 +KIF26B UCSF GRCh37 1 245849530 245849530 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 133 72 63 0 ENST00000407071.2:c.3245C>T p.Pro1082Leu p.P1082L ENST00000407071 NM_018012.3 1082 cCc/cTc 0 +KIF2C UCSF GRCh37 1 45232509 45232509 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 39 22 46 0 ENST00000372224.4:c.1983C>T p.Asp661= p.D661= ENST00000372224 NM_006845.3 661 gaC/gaT 0 +KIF6 UCSF GRCh37 6 39398905 39398905 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 11 32 0 ENST00000287152.7:c.1678G>A p.Glu560Lys p.E560K ENST00000287152 NM_145027.4 560 Gag/Aag 0 +KIFC3 UCSF GRCh37 16 57805320 57805320 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 332 121 87 0 ENST00000379655.4:c.555C>T p.Ser185= p.S185= ENST00000379655 NM_005550.3 185 tcC/tcT 0 +KIT UCSF GRCh37 4 55573358 55573358 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 23 55 0 ENST00000288135.5:c.1020C>T p.Phe340= p.F340= ENST00000288135 NM_000222.2 340 ttC/ttT 0 +KLF11 UCSF GRCh37 2 10188080 10188080 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 52 99 0 ENST00000305883.1:c.616C>T p.Gln206Ter p.Q206* ENST00000305883 NM_003597.4 206 Cag/Tag 0 +KLHDC7A UCSF GRCh37 1 18808738 18808738 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 46 22 0 ENST00000400664.1:c.1263C>T p.Thr421= p.T421= ENST00000400664 NM_152375.2 421 acC/acT 0 +KLHDC7A UCSF GRCh37 1 18808561 18808561 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 28 28 19 0 ENST00000400664.1:c.1086G>A p.Arg362= p.R362= ENST00000400664 NM_152375.2 362 cgG/cgA 0 +KLHDC8A UCSF GRCh37 1 205306545 205306545 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 34 61 0 ENST00000367155.3:c.1035G>A p.Leu345= p.L345= ENST00000367155 NM_018203.2 345 ctG/ctA 0 +KLHL18 UCSF GRCh37 3 47361194 47361194 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 46 89 0 ENST00000232766.5:c.181C>T p.Pro61Ser p.P61S ENST00000232766 NM_025010.4 61 Ccg/Tcg 0 +KLHL8 UCSF GRCh37 4 88116599 88116599 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 54 98 0 ENST00000273963.5:c.93C>T p.Ser31= p.S31= ENST00000273963 NM_020803.3 31 tcC/tcT 0 +KLHL9 UCSF GRCh37 9 21333274 21333274 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 137 109 201 0 ENST00000359039.4:c.1585G>A p.Ala529Thr p.A529T ENST00000359039 529 Gcc/Acc 0 +KLHL9 UCSF GRCh37 9 21334451 21334451 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 130 15 76 0 ENST00000359039.4:c.408C>T p.Pro136= p.P136= ENST00000359039 136 ccC/ccT 0 +KLK1 UCSF GRCh37 19 51325008 51325008 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 11 20 0 ENST00000301420.2:c.166C>T p.His56Tyr p.H56Y ENST00000301420 NM_002257.3 56 Cac/Tac 0 +KLRAQ1 UCSF GRCh37 2 48688356 48688356 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 27 43 0 ENST00000294952.8:c.679C>T p.Pro227Ser p.P227S ENST00000294952 NM_001135629.2 227 Cct/Tct 0 +KPNA1 UCSF GRCh37 3 122172726 122172726 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 11 39 0 ENST00000344337.6:c.555C>T p.Val185= p.V185= ENST00000344337 NM_002264.3 185 gtC/gtT 0 +KPTN UCSF GRCh37 19 47978723 47978723 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 14 8 0 ENST00000338134.3:c.1261G>A p.Gly421Arg p.G421R ENST00000338134 NM_007059.2 421 Ggg/Agg 0 +KPTN UCSF GRCh37 19 47987232 47987232 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 45 21 0 ENST00000338134.3:c.186C>T p.Ile62= p.I62= ENST00000338134 NM_007059.2 62 atC/atT 0 +KRT10 UCSF GRCh37 17 38978210 38978210 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 54 130 0 ENST00000269576.5:c.627+1G>A p.X209_splice ENST00000269576 NM_000421.3 0 +KRT12 UCSF GRCh37 17 39019780 39019780 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 48 45 0 ENST00000251643.4:c.1052C>T p.Ala351Val p.A351V ENST00000251643 NM_000223.3 351 gCc/gTc 0 +KRT24 UCSF GRCh37 17 38859558 38859558 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 166 99 115 0 ENST00000264651.2:c.388G>A p.Val130Ile p.V130I ENST00000264651 NM_019016.2 130 Gtt/Att 0 +KRT33A UCSF GRCh37 17 39506671 39506671 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 48 67 0 ENST00000007735.3:c.348+1G>A p.X116_splice ENST00000007735 NM_004138.3 0 +KRT33A UCSF GRCh37 17 39503373 39503373 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 57 34 49 0 ENST00000007735.3:c.690T>C p.Ser230= p.S230= ENST00000007735 NM_004138.3 230 agT/agC 0 +KRT85 UCSF GRCh37 12 52756135 52756135 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 50 61 0 ENST00000257901.3:c.1198G>A p.Ala400Thr p.A400T ENST00000257901 NM_002283.3 400 Gcc/Acc 0 +KRTAP4-8 UCSF GRCh37 17 39254082 39254082 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 130 45 47 0 ENST00000333822.4:c.255C>T p.Cys85= p.C85= ENST00000333822 NM_031960.2 85 tgC/tgT 0 +KRTAP9-1 UCSF GRCh37 17 39346626 39346627 + protein_altering_variant In_Frame_Ins INS - - GTGGGTCCAGCTGCTGCCAGCCTTGCT NOVEL P05_Rec Untested WXS Illumina HiSeq 8 0 ENST00000398470.1:c.488_489insGTGGGTCCAGCTGCTGCCAGCCTTGCT p.Cys163delinsTrpTrpValGlnLeuLeuProAlaLeuLeu p.C163delinsWWVQLLPALL ENST00000398470 NM_001190460.1 163 tgc/tgGTGGGTCCAGCTGCTGCCAGCCTTGCTc 0 +KRTDAP UCSF GRCh37 19 35981326 35981326 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 21 31 0 ENST00000338897.3:c.19C>T p.Pro7Ser p.P7S ENST00000338897 NM_207392.2 7 Cct/Tct 0 +KTI12 UCSF GRCh37 1 52498894 52498894 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 126 65 53 0 ENST00000371614.1:c.540G>A p.Gly180= p.G180= ENST00000371614 NM_138417.2 180 ggG/ggA 0 +L3MBTL2 UCSF GRCh37 22 41621036 41621036 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 40 34 0 ENST00000216237.5:c.1317C>T p.Pro439= p.P439= ENST00000216237 NM_031488.4 439 ccC/ccT 0 +LAMA1 UCSF GRCh37 18 7043231 7043231 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 72 139 0 ENST00000389658.3:c.1150C>T p.His384Tyr p.H384Y ENST00000389658 NM_005559.3 384 Cac/Tac 0 +LAMB1 UCSF GRCh37 7 107601033 107601033 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 30 55 0 ENST00000222399.6:c.2171G>A p.Gly724Glu p.G724E ENST00000222399 NM_002291.2 724 gGg/gAg 0 +LAMB2 UCSF GRCh37 3 49168206 49168206 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 126 43 84 0 ENST00000305544.4:c.1003C>T p.Pro335Ser p.P335S ENST00000305544 335 Ccg/Tcg 0 +LAMB2 UCSF GRCh37 3 49160387 49160387 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 38 38 0 ENST00000305544.4:c.4323C>T p.Ser1441= p.S1441= ENST00000305544 1441 agC/agT 0 +LAMC3 UCSF GRCh37 9 133961052 133961052 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 24 31 0 ENST00000361069.4:c.4172C>T p.Ser1391Phe p.S1391F ENST00000361069 NM_006059.3 1391 tCc/tTc 0 +LAMC3 UCSF GRCh37 9 133944397 133944397 + stop_gained Nonsense_Mutation SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 144 50 37 0 ENST00000361069.4:c.2850C>A p.Cys950Ter p.C950* ENST00000361069 NM_006059.3 950 tgC/tgA 0 +LARP1 UCSF GRCh37 5 154181876 154181876 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 28 54 0 ENST00000336314.4:c.1795G>A p.Ala599Thr p.A599T ENST00000336314 NM_015315.4 599 Gcc/Acc 0 +LARP1B UCSF GRCh37 4 129012618 129012618 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 24 65 0 ENST00000326639.6:c.619G>A p.Val207Met p.V207M ENST00000326639 NM_018078.3 207 Gtg/Atg 0 +LATS2 UCSF GRCh37 13 21555650 21555650 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 18 51 0 ENST00000382592.4:c.2620G>A p.Val874Met p.V874M ENST00000382592 NM_014572.2 874 Gtg/Atg 0 +LAX1 UCSF GRCh37 1 203743271 203743271 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 29 57 0 ENST00000442561.2:c.659C>T p.Pro220Leu p.P220L ENST00000442561 NM_017773.3 220 cCc/cTc 0 +LAYN UCSF GRCh37 11 111414791 111414791 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 45 71 0 ENST00000375615.3:c.253G>A p.Asp85Asn p.D85N ENST00000375615 NM_001258390.1 85 Gat/Aat 0 +LAYN UCSF GRCh37 11 111425932 111425932 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 36 82 0 ENST00000375615.3:c.599G>A p.Gly200Asp p.G200D ENST00000375615 NM_001258390.1 200 gGt/gAt 0 +LCA5L UCSF GRCh37 21 40777899 40777899 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 29 36 0 ENST00000288350.3:c.1922C>T p.Thr641Ile p.T641I ENST00000288350 641 aCc/aTc 0 +LCA5L UCSF GRCh37 21 40778307 40778307 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 34 88 0 ENST00000288350.3:c.1514C>T p.Thr505Ile p.T505I ENST00000288350 505 aCa/aTa 0 +LCE1E UCSF GRCh37 1 152760093 152760093 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.064,1000g2011may_all_0.1443,snp132_rs112600788 P05_Rec Untested WXS Illumina HiSeq 100 15 24 0 ENST00000368770.3:c.318T>C p.Cys106= p.C106= ENST00000368770 NM_178353.1 106 tgT/tgC 0 +LCE5A UCSF GRCh37 1 152484018 152484018 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 112 61 71 0 ENST00000334269.2:c.8G>A p.Cys3Tyr p.C3Y ENST00000334269 NM_178438.4 3 tGc/tAc 0 +LCK UCSF GRCh37 1 32751132 32751132 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 21 42 0 ENST00000336890.5:c.1345G>A p.Val449Met p.V449M ENST00000336890 NM_005356.3 449 Gtg/Atg 0 +LCN10 UCSF GRCh37 9 139635365 139635365 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 35 30 0 ENST00000474369.1:c.359C>T p.Ser120Phe p.S120F ENST00000474369 120 tCc/tTc 0 +LEMD1 UCSF GRCh37 1 205385359 205385359 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 45 39 0 ENST00000367151.2:c.147+1G>A p.X49_splice ENST00000367151 NM_001199051.1 0 +LEO1 UCSF GRCh37 15 52258437 52258437 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 76 135 0 ENST00000299601.5:c.323G>A p.Ser108Asn p.S108N ENST00000299601 NM_138792.2 108 aGt/aAt 0 +LETMD1 UCSF GRCh37 12 51445875 51445875 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 41 116 0 ENST00000262055.4:c.275G>A p.Gly92Glu p.G92E ENST00000262055 NM_015416.4 92 gGa/gAa 0 +LILRB3 UCSF GRCh37 19 54725744 54725744 + stop_gained Nonsense_Mutation SNP C C T 1000g2011may_all_0.0238,snp132_rs59533602 P05_Rec Untested WXS Illumina HiSeq 45 8 24 0 ENST00000245620.9:c.614G>A p.Trp205Ter p.W205* ENST00000245620 205 tGg/tAg 0 +LILRB3 UCSF GRCh37 19 54725755 54725755 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.020,1000g2011may_all_0.1385,snp132_rs1052971 P05_Rec Untested WXS Illumina HiSeq 43 7 20 1 ENST00000245620.9:c.603A>G p.Thr201= p.T201= ENST00000245620 201 acA/acG 0 +LILRB4 UCSF GRCh37 19 55175893 55175893 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 45 70 0 ENST00000391736.1:c.612C>T p.Tyr204= p.Y204= ENST00000391736 NM_001278430.2 204 taC/taT 0 +LIMCH1 UCSF GRCh37 4 41648199 41648199 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 51 62 0 ENST00000313860.7:c.1158G>A p.Glu386= p.E386= ENST00000313860 NM_014988.2 386 gaG/gaA 0 +LINGO2 UCSF GRCh37 9 27948893 27948893 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 46 82 0 ENST00000308675.3:c.1777G>A p.Gly593Arg p.G593R ENST00000308675 593 Ggg/Agg 0 +LINS UCSF GRCh37 15 101114038 101114038 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 44 142 0 ENST00000314742.8:c.1040C>T p.Ser347Leu p.S347L ENST00000314742 NM_001040616.2 347 tCg/tTg 0 +LMBRD2 UCSF GRCh37 5 36143394 36143394 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 33 40 0 ENST00000296603.4:c.58C>T p.Leu20= p.L20= ENST00000296603 NM_001007527.1 20 Ctg/Ttg 0 +LMLN UCSF GRCh37 3 197748316 197748316 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 26 122 0 ENST00000330198.4:c.1366-1G>A p.X456_splice ENST00000330198 NM_033029.3 0 +LMTK2 UCSF GRCh37 7 97821211 97821211 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 36 57 0 ENST00000297293.5:c.1434G>A p.Trp478Ter p.W478* ENST00000297293 NM_014916.3 478 tgG/tgA 0 +LOC100130357 UCSF GRCh37 6 13281226 13281226 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 34 58 0 ENST00000606150.1:n.606C>T *202* ENST00000606150 0 +LOC100653515 UCSF GRCh37 17 76887469 76887469 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 61 75 0 ENST00000322630.2:c.1117C>T p.Pro373Ser p.P373S ENST00000322630 NM_001243540.1 373 Cct/Tct 0 +LOC81691 UCSF GRCh37 16 20837259 20837259 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 32 70 0 ENST00000261377.6:c.810C>T p.Asp270= p.D270= ENST00000261377 NM_030941.2 270 gaC/gaT 0 +LOXL1 UCSF GRCh37 15 74239441 74239441 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 22 51 0 ENST00000261921.7:c.1383C>T p.Tyr461= p.Y461= ENST00000261921 NM_005576.2 461 taC/taT 0 +LPHN1 UCSF GRCh37 19 14271099 14271099 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 23 17 0 ENST00000340736.6:c.1640G>A p.Gly547Glu p.G547E ENST00000340736 NM_001008701.2 547 gGg/gAg 0 +LPP UCSF GRCh37 3 188327481 188327481 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 43 83 0 ENST00000312675.4:c.962G>A p.Gly321Asp p.G321D ENST00000312675 NM_005578.3 321 gGt/gAt 0 +LRIG3 UCSF GRCh37 12 59271268 59271268 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 24 56 0 ENST00000320743.3:c.2450G>A p.Cys817Tyr p.C817Y ENST00000320743 NM_153377.4 817 tGc/tAc 0 +LRP1 UCSF GRCh37 12 57599204 57599204 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 37 22 0 ENST00000243077.3:c.11406G>A p.Glu3802= p.E3802= ENST00000243077 NM_002332.2 3802 gaG/gaA 0 +LRP1B UCSF GRCh37 2 141115574 141115574 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 43 72 0 ENST00000389484.3:c.11369G>A p.Gly3790Asp p.G3790D ENST00000389484 NM_018557.2 3790 gGt/gAt 0 +LRP2 UCSF GRCh37 2 170136105 170136105 + missense_variant,splice_region_variant Missense_Mutation SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 24 34 0 ENST00000263816.3:c.1342G>T p.Val448Phe p.V448F ENST00000263816 NM_004525.2 448 Gtt/Ttt 0 +LRRC16B UCSF GRCh37 14 24531705 24531705 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 111 80 105 0 ENST00000342740.5:c.2497G>A p.Val833Ile p.V833I ENST00000342740 NM_138360.3 833 Gtc/Atc 0 +LRRC37A3 UCSF GRCh37 17 62856791 62856791 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 151 100 141 0 ENST00000319651.5:c.3473G>A p.Gly1158Asp p.G1158D ENST00000319651 1158 gGc/gAc 0 +LRRC37B UCSF GRCh37 17 30374838 30374838 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 177 107 160 0 ENST00000341671.7:c.2301G>A p.Arg767= p.R767= ENST00000341671 NM_052888.2 767 cgG/cgA 0 +LRRC48 UCSF GRCh37 17 17907751 17907751 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 43 71 0 ENST00000313838.8:c.1074C>T p.Ile358= p.I358= ENST00000313838 NM_001130090.1 358 atC/atT 0 +LRRC4C UCSF GRCh37 11 40136757 40136757 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 52 100 0 ENST00000278198.2:c.1086C>T p.Asp362= p.D362= ENST00000278198 362 gaC/gaT 0 +LRRC59 UCSF GRCh37 17 48474579 48474579 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 41 22 0 ENST00000225972.7:c.100G>A p.Glu34Lys p.E34K ENST00000225972 NM_018509.3 34 Gag/Aag 0 +LRRC61 UCSF GRCh37 7 150034385 150034385 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 25 31 0 ENST00000323078.7:c.435C>T p.Ser145= p.S145= ENST00000323078 NM_023942.2 145 tcC/tcT 0 +LRRC7 UCSF GRCh37 1 70541956 70541956 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 33 68 0 ENST00000035383.5:c.4313G>A p.Arg1438Lys p.R1438K ENST00000035383 NM_020794.2 1438 aGg/aAg 0 +LRRC71 UCSF GRCh37 1 156899150 156899150 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 25 53 0 ENST00000337428.7:c.1075G>A p.Val359Met p.V359M ENST00000337428 NM_144702.2 359 Gtg/Atg 0 +LRRC8E UCSF GRCh37 19 7964090 7964090 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 33 35 0 ENST00000306708.6:c.683G>A p.Gly228Asp p.G228D ENST00000306708 NM_025061.4 228 gGt/gAt 0 +LRRFIP1 UCSF GRCh37 2 238671627 238671627 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 35 103 0 ENST00000392000.4:c.1271G>A p.Gly424Glu p.G424E ENST00000392000 NM_001137552.1 424 gGa/gAa 0 +LRRN4CL UCSF GRCh37 11 62455781 62455781 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 7 8 0 ENST00000317449.4:c.200G>A p.Gly67Glu p.G67E ENST00000317449 NM_203422.3 67 gGg/gAg 0 +LRTM1 UCSF GRCh37 3 54958759 54958759 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 29 74 0 ENST00000273286.5:c.491C>T p.Ala164Val p.A164V ENST00000273286 NM_020678.2 164 gCg/gTg 0 +LSM12 UCSF GRCh37 17 42141194 42141194 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 19 45 0 ENST00000293406.3:c.233C>T p.Pro78Leu p.P78L ENST00000293406 78 cCc/cTc 0 +LSR UCSF GRCh37 19 35739826 35739826 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 36 25 0 ENST00000361790.3:c.45G>A p.Gly15= p.G15= ENST00000361790 NM_205834.3 15 ggG/ggA 0 +LTBP1 UCSF GRCh37 2 33623560 33623560 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 33 68 0 ENST00000404816.2:c.5114G>A p.Cys1705Tyr p.C1705Y ENST00000404816 1705 tGc/tAc 0 +LUZP4 UCSF GRCh37 X 114537919 114537919 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 84 105 0 ENST00000371920.3:c.278C>T p.Ser93Phe p.S93F ENST00000371920 NM_016383.3 93 tCc/tTc 0 +LY6D UCSF GRCh37 8 143866676 143866676 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 16 11 0 ENST00000301263.4:c.348C>T p.Ala116= p.A116= ENST00000301263 NM_003695.2 116 gcC/gcT 0 +LY6G6F UCSF GRCh37 6 31675728 31675728 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 30 77 0 ENST00000375832.4:c.463G>A p.Asp155Asn p.D155N ENST00000375832 NM_001003693.1 155 Gac/Aac 0 +LY75 UCSF GRCh37 2 160738710 160738710 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 65 110 0 ENST00000263636.4:c.1171G>A p.Ala391Thr p.A391T ENST00000263636 NM_002349.3 391 Gcc/Acc 0 +LY9 UCSF GRCh37 1 160793410 160793410 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 51 71 0 ENST00000263285.6:c.1654G>A p.Val552Met p.V552M ENST00000263285 552 Gtg/Atg 0 +LY9 UCSF GRCh37 1 160784304 160784304 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 24 49 0 ENST00000263285.6:c.825G>A p.Arg275= p.R275= ENST00000263285 275 cgG/cgA 0 +LYZL1 UCSF GRCh37 10 29581576 29581576 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 34 79 0 ENST00000375500.3:c.406G>A p.Glu136Lys p.E136K ENST00000375500 NM_032517.4 136 Gag/Aag 0 +LZIC UCSF GRCh37 1 9995591 9995591 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 118 60 106 0 ENST00000377213.1:c.196G>A p.Gly66Arg p.G66R ENST00000377213 66 Gga/Aga 0 +LZTS2 UCSF GRCh37 10 102763808 102763808 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 23 28 0 ENST00000370220.1:c.953C>T p.Pro318Leu p.P318L ENST00000370220 318 cCt/cTt 0 +MACF1 UCSF GRCh37 1 39823224 39823224 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 33 64 0 ENST00000372915.3:c.11617G>A p.Glu3873Lys p.E3873K ENST00000372915 3873 Gaa/Aaa 0 +MACF1 UCSF GRCh37 1 39905119 39905119 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 25 66 0 ENST00000372915.3:c.18091G>A p.Glu6031Lys p.E6031K ENST00000372915 6031 Gaa/Aaa 0 +MACF1 UCSF GRCh37 1 39916782 39916782 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 37 70 0 ENST00000372915.3:c.20014G>A p.Ala6672Thr p.A6672T ENST00000372915 6672 Gca/Aca 0 +MAD1L1 UCSF GRCh37 7 2054237 2054237 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 12 12 0 ENST00000265854.7:c.1259G>A p.Ser420Asn p.S420N ENST00000265854 420 aGc/aAc 0 +MAG UCSF GRCh37 19 35786832 35786832 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 163 108 91 0 ENST00000392213.3:c.363G>A p.Leu121= p.L121= ENST00000392213 NM_002361.3 121 ctG/ctA 0 +MAGEE2 UCSF GRCh37 X 75004566 75004566 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 22 31 0 ENST00000373359.2:c.321G>A p.Gly107= p.G107= ENST00000373359 NM_138703.4 107 ggG/ggA 0 +MAGI2 UCSF GRCh37 7 78131015 78131015 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 120 29 61 0 ENST00000354212.4:c.844G>A p.Glu282Lys p.E282K ENST00000354212 NM_012301.3 282 Gag/Aag 0 +MALL UCSF GRCh37 2 110849244 110849244 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 20 93 0 ENST00000272462.2:c.209C>T p.Ser70Phe p.S70F ENST00000272462 NM_005434.4 70 tCc/tTc 0 +MALL UCSF GRCh37 2 110849239 110849239 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 83 19 90 0 ENST00000272462.2:c.214A>C p.Met72Leu p.M72L ENST00000272462 NM_005434.4 72 Atg/Ctg 0 +MAN1A1 UCSF GRCh37 6 119623264 119623264 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 19 39 0 ENST00000368468.3:c.705C>T p.Asn235= p.N235= ENST00000368468 NM_005907.3 235 aaC/aaT 0 +MAN2C1 UCSF GRCh37 15 75648258 75648258 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 27 19 0 ENST00000267978.5:c.3112C>T p.Pro1038Ser p.P1038S ENST00000267978 NM_006715.3 1038 Ccg/Tcg 0 +MANSC1 UCSF GRCh37 12 12483769 12483769 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 32 91 0 ENST00000535902.1:c.488C>T p.Pro163Leu p.P163L ENST00000535902 163 cCc/cTc 0 +MAP1A UCSF GRCh37 15 43822285 43822285 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 48 77 0 ENST00000300231.5:c.8275C>T p.His2759Tyr p.H2759Y ENST00000300231 2759 Cat/Tat 0 +MAP1A UCSF GRCh37 15 43821976 43821976 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 36 27 0 ENST00000300231.5:c.8164G>A p.Val2722Ile p.V2722I ENST00000300231 2722 Gtc/Atc 0 +MAP2 UCSF GRCh37 2 210559366 210559366 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 137 71 123 0 ENST00000360351.4:c.2472A>G p.Ala824= p.A824= ENST00000360351 NM_002374.3 824 gcA/gcG 0 +MAP3K12 UCSF GRCh37 12 53881086 53881086 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 42 39 0 ENST00000267079.2:c.90C>T p.Asp30= p.D30= ENST00000267079 NM_006301.3 30 gaC/gaT 0 +MAP3K13 UCSF GRCh37 3 185161342 185161342 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 29 89 0 ENST00000265026.3:c.769G>A p.Val257Ile p.V257I ENST00000265026 NM_004721.4 257 Gta/Ata 0 +MAP3K15 UCSF GRCh37 X 19478195 19478195 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 63 122 0 ENST00000338883.4:c.796G>A p.Glu266Lys p.E266K ENST00000338883 NM_001001671.3 266 Gag/Aag 0 +MAP3K2 UCSF GRCh37 2 128075877 128075877 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 74 118 0 ENST00000344908.5:c.1062C>T p.Thr354= p.T354= ENST00000344908 NM_006609.4 354 acC/acT 0 +MAP3K6 UCSF GRCh37 1 27690766 27690766 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 31 29 0 ENST00000357582.2:c.624G>A p.Gly208= p.G208= ENST00000357582 208 ggG/ggA 0 +MAP4K1 UCSF GRCh37 19 39086617 39086617 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 56 66 0 ENST00000591517.1:c.2141C>T p.Thr714Ile p.T714I ENST00000591517 NM_007181.4 714 aCc/aTc 0 +MAP4K4 UCSF GRCh37 2 102460666 102460666 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 45 43 0 ENST00000347699.4:c.1126C>T p.Leu376= p.L376= ENST00000347699 NM_145687.3 376 Cta/Tta 0 +MARCH7 UCSF GRCh37 2 160615737 160615737 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 43 62 0 ENST00000259050.4:c.1784G>A p.Gly595Asp p.G595D ENST00000259050 NM_022826.2 595 gGt/gAt 0 +MARK2 UCSF GRCh37 11 63670230 63670230 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 21 16 0 ENST00000402010.2:c.1392G>A p.Lys464= p.K464= ENST00000402010 NM_001039469.2 464 aaG/aaA 0 +MAST3 UCSF GRCh37 19 18232506 18232506 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 104 83 55 0 ENST00000262811.6:c.83G>A p.Gly28Glu p.G28E ENST00000262811 NM_015016.1 28 gGg/gAg 0 +MAT2A UCSF GRCh37 2 85769819 85769819 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 38 48 0 ENST00000306434.3:c.900G>A p.Trp300Ter p.W300* ENST00000306434 NM_005911.5 300 tgG/tgA 0 +MATN4 UCSF GRCh37 20 43932943 43932943 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 37 9 0 ENST00000372754.1:c.568G>A p.Asp190Asn p.D190N ENST00000372754 190 Gac/Aac 0 +MATR3 UCSF GRCh37 5 138643547 138643547 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 47 74 0 ENST00000394805.3:c.443G>A p.Arg148Lys p.R148K ENST00000394805 NM_001194955.1 148 aGg/aAg 0 +MAX UCSF GRCh37 14 65472892 65472898 + intron_variant Intron INS GCCACCA GCCACCA TGCCCCCT NOVEL P05_Rec Untested WXS Illumina HiSeq 6 0 ENST00000246166.2:c.209+1861_209+1867delinsTGCCCCCT *70* ENST00000246166 NM_002028.3 0 +MBD6 UCSF GRCh37 12 57919877 57919877 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 40 55 0 ENST00000355673.3:c.1126C>T p.Leu376= p.L376= ENST00000355673 NM_052897.3 376 Cta/Tta 0 +MBIP UCSF GRCh37 14 36783783 36783783 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 21 11 0 ENST00000416007.4:c.506G>A p.Arg169Lys p.R169K ENST00000416007 NM_016586.2 169 aGa/aAa 0 +MCCC2 UCSF GRCh37 5 70945963 70945963 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 68 110 0 ENST00000340941.6:c.1441G>A p.Val481Met p.V481M ENST00000340941 NM_022132.4 481 Gtg/Atg 0 +MCM2 UCSF GRCh37 3 127338011 127338011 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 22 33 0 ENST00000265056.7:c.2155G>A p.Val719Ile p.V719I ENST00000265056 NM_004526.3 719 Gtc/Atc 0 +MCOLN1 UCSF GRCh37 19 7591679 7591679 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 32 31 0 ENST00000264079.6:c.438G>A p.Arg146= p.R146= ENST00000264079 NM_020533.2 146 cgG/cgA 0 +MDC1 UCSF GRCh37 6 30680044 30680044 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 37 62 0 ENST00000376406.3:c.1675C>T p.Pro559Ser p.P559S ENST00000376406 NM_014641.2 559 Cca/Tca 0 +MDFIC UCSF GRCh37 7 114655875 114655875 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 242 63 165 0 ENST00000393486.1:c.627G>A p.Gly209= p.G209= ENST00000393486 NM_001166345.1 209 ggG/ggA 0 +MDGA1 UCSF GRCh37 6 37614108 37614108 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 18 27 0 ENST00000434837.3:c.2090G>A p.Arg697His p.R697H ENST00000434837 NM_153487.3 697 cGt/cAt 0 +MDGA1 UCSF GRCh37 6 37619918 37619918 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 29 40 0 ENST00000434837.3:c.1181C>T p.Pro394Leu p.P394L ENST00000434837 NM_153487.3 394 cCc/cTc 0 +MDM4 UCSF GRCh37 1 204511996 204511996 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 47 90 0 ENST00000367182.3:c.596C>T p.Pro199Leu p.P199L ENST00000367182 NM_001278516.1 199 cCt/cTt 0 +MED1 UCSF GRCh37 17 37566483 37566483 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 46 118 0 ENST00000300651.6:c.1991G>A p.Ser664Asn p.S664N ENST00000300651 NM_004774.3 664 aGc/aAc 0 +MED22 UCSF GRCh37 9 136211168 136211168 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 119 62 59 0 ENST00000343730.5:c.225G>A p.Leu75= p.L75= ENST00000343730 NM_133640.4 75 ctG/ctA 0 +MED23 UCSF GRCh37 6 131917238 131917238 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 64 116 0 ENST00000368068.3:c.2844G>A p.Gln948= p.Q948= ENST00000368068 NM_004830.3 948 caG/caA 0 +MED23 UCSF GRCh37 6 131949151 131949151 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 36 50 0 ENST00000368068.3:c.39G>A p.Val13= p.V13= ENST00000368068 NM_004830.3 13 gtG/gtA 0 +MED24 UCSF GRCh37 17 38182450 38182450 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.00098 P05_Rec Untested WXS Illumina HiSeq 119 68 73 0 ENST00000394128.2:c.1944G>A p.Gly648= p.G648= ENST00000394128 NM_014815.3 648 ggG/ggA 0 +MEF2B UCSF GRCh37 19 19257881 19257881 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 6 8 0 ENST00000162023.5:c.505C>T p.Pro169Ser p.P169S ENST00000162023 169 Ccc/Tcc 0 +MEIG1 UCSF GRCh37 10 15014527 15014527 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 20 87 0 ENST00000378240.1:c.154G>A p.Glu52Lys p.E52K ENST00000378240 52 Gag/Aag 0 +MEIS2 UCSF GRCh37 15 37184661 37184661 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 71 108 0 ENST00000561208.1:c.1148-1G>A p.X383_splice ENST00000561208 0 +METAP2 UCSF GRCh37 12 95887890 95887890 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 36 59 0 ENST00000323666.5:c.487G>A p.Glu163Lys p.E163K ENST00000323666 NM_006838.3 163 Gaa/Aaa 0 +METTL21D UCSF GRCh37 14 50582895 50582895 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 81 99 0 ENST00000395860.2:c.269C>T p.Ala90Val p.A90V ENST00000395860 NM_024558.2 90 gCt/gTt 0 +MFAP4 UCSF GRCh37 17 19287934 19287934 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 20 35 0 ENST00000299610.4:c.609C>T p.Ser203= p.S203= ENST00000299610 NM_002404.2 203 tcC/tcT 0 +MFSD11 UCSF GRCh37 17 74771103 74771103 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 159 67 133 0 ENST00000336509.4:c.899G>A p.Ser300Asn p.S300N ENST00000336509 NM_001242533.1 300 aGc/aAc 0 +MGAM UCSF GRCh37 7 141738364 141738364 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 9 34 0 ENST00000549489.2:c.2265C>T p.His755= p.H755= ENST00000549489 NM_004668.2 755 caC/caT 0 +MGAT2 UCSF GRCh37 14 50088200 50088200 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 26 32 0 ENST00000305386.2:c.214G>A p.Ala72Thr p.A72T ENST00000305386 NM_002408.3 72 Gcg/Acg 0 +MGAT3 UCSF GRCh37 22 39884476 39884476 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 78 22 0 ENST00000341184.6:c.1124G>A p.Gly375Glu p.G375E ENST00000341184 NM_002409.4 375 gGg/gAg 0 +MGRN1 UCSF GRCh37 16 4731676 4731676 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 57 27 0 ENST00000399577.5:c.1257C>T p.Ile419= p.I419= ENST00000399577 NM_001142290.2 419 atC/atT 0 +MIA2 4253 UCSF GRCh37 14 39703402 39703402 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 145 53 157 0 ENST00000280082.3:c.84C>T p.Asp28= p.D28= ENST00000280082 NM_054024.3 28 gaC/gaT 0 +MIB1 UCSF GRCh37 18 19378066 19378066 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 44 88 0 ENST00000261537.6:c.1114G>A p.Val372Ile p.V372I ENST00000261537 NM_020774.3 372 Gta/Ata 0 +MILR1 UCSF GRCh37 17 62462747 62462747 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 41 51 0 ENST00000605096.1:c.184C>T p.Pro62Leu p.P62L ENST00000605096 NM_001085423.1 62 cCc/cTc 0 +MIXL1 UCSF GRCh37 1 226413277 226413277 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 53 80 0 ENST00000366810.5:c.463C>T p.Pro155Ser p.P155S ENST00000366810 155 Ccg/Tcg 0 +MKNK1 UCSF GRCh37 1 47048942 47048942 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 39 88 0 ENST00000371946.4:c.94C>T p.Arg32Trp p.R32W ENST00000371946 NM_003684.5 32 Cgg/Tgg 0 +MKS1 UCSF GRCh37 17 56294080 56294080 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 15 42 0 ENST00000393119.2:c.208G>A p.Glu70Lys p.E70K ENST00000393119 NM_017777.3 70 Gaa/Aaa 0 +MLL2 UCSF GRCh37 12 49424208 49424208 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 6 10 12 0 ENST00000301067.7:c.13854C>T p.Asn4618= p.N4618= ENST00000301067 NM_003482.3 4618 aaC/aaT 0 +MLL2 UCSF GRCh37 12 49432034 49432034 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 58 72 0 ENST00000301067.7:c.9105C>T p.Asp3035= p.D3035= ENST00000301067 NM_003482.3 3035 gaC/gaT 0 +MLL3 UCSF GRCh37 7 151835881 151835881 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 250 45 132 0 ENST00000262189.6:c.14643G>A p.Glu4881= p.E4881= ENST00000262189 NM_170606.2 4881 gaG/gaA 0 +MLLT4 UCSF GRCh37 6 168319538 168319538 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 21 44 0 ENST00000447894.2:c.2812G>A p.Asp938Asn p.D938N ENST00000447894 938 Gat/Aat 0 +MLLT6 UCSF GRCh37 17 36880878 36880878 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 14 15 0 ENST00000325718.7:c.2889C>T p.His963= p.H963= ENST00000325718 NM_005937.3 963 caC/caT 0 +MLNR UCSF GRCh37 13 49795343 49795343 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 16 10 0 ENST00000218721.1:c.870G>A p.Glu290= p.E290= ENST00000218721 NM_001507.1 290 gaG/gaA 0 +MLYCD UCSF GRCh37 16 83948616 83948616 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 344 144 159 0 ENST00000262430.4:c.1004C>T p.Thr335Ile p.T335I ENST00000262430 NM_012213.2 335 aCc/aTc 0 +MMAA UCSF GRCh37 4 146572288 146572288 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 31 44 0 ENST00000281317.5:c.808G>A p.Asp270Asn p.D270N ENST00000281317 NM_172250.2 270 Gat/Aat 0 +MMAA UCSF GRCh37 4 146575229 146575229 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 55 112 0 ENST00000281317.5:c.903G>A p.Arg301= p.R301= ENST00000281317 NM_172250.2 301 agG/agA 0 +MMP14 UCSF GRCh37 14 23311145 23311145 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 52 69 0 ENST00000311852.6:c.281G>A p.Gly94Asp p.G94D ENST00000311852 NM_004995.3 94 gGt/gAt 0 +MMP15 UCSF GRCh37 16 58079067 58079067 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 18 14 0 ENST00000219271.3:c.1727C>T p.Pro576Leu p.P576L ENST00000219271 NM_002428.2 576 cCc/cTc 0 +MMP16 UCSF GRCh37 8 89339416 89339416 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 60 74 0 ENST00000286614.6:c.20G>A p.Ser7Asn p.S7N ENST00000286614 NM_005941.4 7 aGc/aAc 0 +MMP17 UCSF GRCh37 12 132329946 132329946 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 48 18 8 0 ENST00000360564.1:c.1156G>A p.Asp386Asn p.D386N ENST00000360564 NM_016155.4 386 Gac/Aac 0 +MMP24 UCSF GRCh37 20 33839763 33839763 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 184 57 181 0 ENST00000246186.6:c.451C>T p.Arg151Trp p.R151W ENST00000246186 NM_006690.3 151 Cgg/Tgg 0 +MN1 UCSF GRCh37 22 28194159 28194159 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 55 32 16 0 ENST00000302326.4:c.2373C>T p.Phe791= p.F791= ENST00000302326 NM_002430.2 791 ttC/ttT 0 +MOBP UCSF GRCh37 3 39543657 39543657 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 158 73 51 0 ENST00000420739.1:c.97C>T p.Leu33Phe p.L33F ENST00000420739 33 Ctc/Ttc 0 +MOV10 UCSF GRCh37 1 113235546 113235546 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 12 7 15 0 ENST00000357443.2:c.1135C>T p.Leu379= p.L379= ENST00000357443 379 Ctg/Ttg 0 +MPDZ UCSF GRCh37 9 13183527 13183527 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 132 76 107 0 ENST00000319217.7:c.2539C>T p.Pro847Ser p.P847S ENST00000319217 NM_001261406.1 847 Cct/Tct 0 +MPP1 UCSF GRCh37 X 154018261 154018261 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 20 43 0 ENST00000369534.3:c.448C>T p.Pro150Ser p.P150S ENST00000369534 NM_001166461.1 150 Ccc/Tcc 0 +MPP3 UCSF GRCh37 17 41891415 41891415 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 76 106 0 ENST00000398389.4:c.1219G>A p.Ala407Thr p.A407T ENST00000398389 NM_001932.4 407 Gct/Act 0 +MPP3 UCSF GRCh37 17 41901303 41901303 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 27 43 0 ENST00000398389.4:c.680G>A p.Ser227Asn p.S227N ENST00000398389 NM_001932.4 227 aGc/aAc 0 +MRC2 UCSF GRCh37 17 60741999 60741999 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 47 47 0 ENST00000303375.5:c.209C>T p.Thr70Ile p.T70I ENST00000303375 NM_006039.4 70 aCc/aTc 0 +MRPL24 UCSF GRCh37 1 156708209 156708209 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 125 99 168 0 ENST00000361531.2:c.205G>A p.Asp69Asn p.D69N ENST00000361531 69 Gat/Aat 0 +MRPS17 UCSF GRCh37 7 56022616 56022616 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 278 93 183 0 ENST00000285298.4:c.138G>A p.Arg46= p.R46= ENST00000285298 NM_015969.2 46 cgG/cgA 0 +MRPS21 UCSF GRCh37 1 150266816 150266816 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 21 47 0 ENST00000369084.5:c.30G>A p.Arg10= p.R10= ENST00000369084 NM_018997.3 10 agG/agA 0 +MRPS24 UCSF GRCh37 7 43906315 43906315 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 23 76 0 ENST00000317534.5:c.487G>A p.Val163Met p.V163M ENST00000317534 NM_032014.2 163 Gtg/Atg 0 +MSH6 UCSF GRCh37 2 48030615 48030615 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 20 38 57 0 ENST00000234420.5:c.3229C>T p.Pro1077Ser p.P1077S ENST00000234420 NM_000179.2 1077 Cca/Tca 0 +MSL2 UCSF GRCh37 3 135871035 135871035 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 22 42 0 ENST00000309993.2:c.688G>A p.Asp230Asn p.D230N ENST00000309993 NM_018133.3 230 Gat/Aat 0 +MSLNL UCSF GRCh37 16 823159 823159 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 42 28 0 ENST00000442466.1:c.1056C>T p.Cys352= p.C352= ENST00000442466 352 tgC/tgT 0 +MST1R UCSF GRCh37 3 49928724 49928724 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 19 34 0 ENST00000296474.3:c.3550G>A p.Asp1184Asn p.D1184N ENST00000296474 NM_002447.2 1184 Gac/Aac 0 +MT1A UCSF GRCh37 16 56673188 56673188 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 133 23 81 0 ENST00000290705.8:c.41C>T p.Thr14Ile p.T14I ENST00000290705 NM_005946.2 14 aCc/aTc 0 +MTCH1 UCSF GRCh37 6 36940490 36940490 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 3 15 0 ENST00000373627.5:c.844G>A p.Val282Met p.V282M ENST00000373627 NM_001271641.1 282 Gtg/Atg 0 +MTERFD2 UCSF GRCh37 2 242038848 242038848 + synonymous_variant,NMD_transcript_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 40 82 0 ENST00000241527.6:c.483G>A p.Lys161= p.K161= ENST00000241527 161 aaG/aaA 0 +MTHFD1 UCSF GRCh37 14 64905841 64905841 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 16 41 0 ENST00000216605.8:c.1625G>A p.Arg542Lys p.R542K ENST00000216605 NM_005956.3 542 aGg/aAg 0 +MTL5 UCSF GRCh37 11 68480777 68480777 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 132 109 0 ENST00000255087.5:c.1119G>A p.Arg373= p.R373= ENST00000255087 NM_004923.3 373 agG/agA 0 +MTMR8 UCSF GRCh37 X 63574685 63574685 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 32 64 0 ENST00000374852.3:c.440C>T p.Thr147Ile p.T147I ENST00000374852 NM_017677.3 147 aCc/aTc 0 +MTMR8 UCSF GRCh37 X 63579408 63579408 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 46 53 0 ENST00000374852.3:c.25-1G>A p.X9_splice ENST00000374852 NM_017677.3 0 +MTNR1A UCSF GRCh37 4 187455161 187455161 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 73 107 0 ENST00000307161.5:c.735C>T p.Val245= p.V245= ENST00000307161 NM_005958.3 245 gtC/gtT 0 +MTPAP UCSF GRCh37 10 30625909 30625909 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 132 61 101 0 ENST00000263063.4:c.603G>A p.Glu201= p.E201= ENST00000263063 NM_018109.3 201 gaG/gaA 0 +MTR UCSF GRCh37 1 236998947 236998947 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 104 62 133 0 ENST00000366577.5:c.1289G>A p.Arg430Lys p.R430K ENST00000366577 NM_000254.2 430 aGa/aAa 0 +MTUS1 UCSF GRCh37 8 17612062 17612062 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 52 73 0 ENST00000262102.6:c.1255G>A p.Val419Ile p.V419I ENST00000262102 NM_001001924.2 419 Gtc/Atc 0 +MUC15 UCSF GRCh37 11 26584798 26584798 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 48 76 0 ENST00000455601.2:c.709G>A p.Gly237Arg p.G237R ENST00000455601 NM_145650.3 237 Gga/Aga 0 +MUC16 UCSF GRCh37 19 9027261 9027261 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 22 29 0 ENST00000397910.4:c.36625G>A p.Asp12209Asn p.D12209N ENST00000397910 NM_024690.2 12209 Gat/Aat 0 +MUC16 UCSF GRCh37 19 9047729 9047729 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 58 81 0 ENST00000397910.4:c.33902C>T p.Ala11301Val p.A11301V ENST00000397910 NM_024690.2 11301 gCa/gTa 0 +MUC16 UCSF GRCh37 19 9067981 9067981 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 108 51 127 0 ENST00000397910.4:c.19465C>T p.Leu6489Phe p.L6489F ENST00000397910 NM_024690.2 6489 Ctt/Ttt 0 +MUC16 UCSF GRCh37 19 9073785 9073785 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 90 123 0 ENST00000397910.4:c.13661C>T p.Thr4554Ile p.T4554I ENST00000397910 NM_024690.2 4554 aCt/aTt 0 +MUC16 UCSF GRCh37 19 9084076 9084076 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 135 78 136 0 ENST00000397910.4:c.7739C>T p.Thr2580Ile p.T2580I ENST00000397910 NM_024690.2 2580 aCa/aTa 0 +MUC16 UCSF GRCh37 19 9084824 9084824 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 65 140 0 ENST00000397910.4:c.6991C>T p.Leu2331Phe p.L2331F ENST00000397910 NM_024690.2 2331 Ctc/Ttc 0 +MUC17 UCSF GRCh37 7 100677195 100677195 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 357 101 228 0 ENST00000306151.4:c.2498C>T p.Ser833Phe p.S833F ENST00000306151 NM_001040105.1 833 tCc/tTc 0 +MUC21 UCSF GRCh37 6 30955956 30955956 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 13 35 0 ENST00000376296.3:c.1686G>A p.Arg562= p.R562= ENST00000376296 NM_001010909.2 562 agG/agA 0 +MUC4 UCSF GRCh37 3 195507907 195507907 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 677 83 477 0 ENST00000463781.3:c.10544C>T p.Thr3515Ile p.T3515I ENST00000463781 NM_018406.6 3515 aCc/aTc 0 +MUC4 UCSF GRCh37 3 195518202 195518202 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 132 111 239 0 ENST00000463781.3:c.249G>A p.Glu83= p.E83= ENST00000463781 NM_018406.6 83 gaG/gaA 0 +MUC4 UCSF GRCh37 3 195510396 195510396 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 60 10 97 1 ENST00000463781.3:c.8055T>G p.His2685Gln p.H2685Q ENST00000463781 NM_018406.6 2685 caT/caG 0 +MUC4 UCSF GRCh37 3 195508523 195508523 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 9 35 1 ENST00000463781.3:c.9928G>A p.Ala3310Thr p.A3310T ENST00000463781 NM_018406.6 3310 Gcc/Acc 0 +MUC5B UCSF GRCh37 11 1250478 1250478 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 10 10 8 0 ENST00000529681.1:c.1055C>T p.Ala352Val p.A352V ENST00000529681 NM_002458.2 352 gCg/gTg 0 +MUC5B UCSF GRCh37 11 1266696 1266696 + synonymous_variant Silent SNP A A C 1000g2011may_all_0.1446,snp132_rs4046509 P05_Rec Untested WXS Illumina HiSeq 22 3 37 0 ENST00000529681.1:c.8586A>C p.Pro2862= p.P2862= ENST00000529681 NM_002458.2 2862 ccA/ccC 0 +MUC6 UCSF GRCh37 11 1017480 1017480 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 530 121 459 0 ENST00000421673.2:c.5321C>T p.Thr1774Ile p.T1774I ENST00000421673 NM_005961.2 1774 aCc/aTc 0 +MUC6 UCSF GRCh37 11 1027375 1027375 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 71 69 0 ENST00000421673.2:c.2124C>T p.Tyr708= p.Y708= ENST00000421673 NM_005961.2 708 taC/taT 0 +MYC UCSF GRCh37 8 128750682 128750682 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 50 17 0 ENST00000377970.2:c.219C>T p.Thr73= p.T73= ENST00000377970 NM_002467.4 73 acC/acT 0 +MYH10 UCSF GRCh37 17 8379127 8379127 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 61 95 0 ENST00000269243.4:c.5926G>A p.Glu1976Lys p.E1976K ENST00000269243 NM_005964.3 1976 Gag/Aag 0 +MYH10 UCSF GRCh37 17 8416891 8416891 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 37 66 0 ENST00000269243.4:c.2617G>A p.Gly873Arg p.G873R ENST00000269243 NM_005964.3 873 Gga/Aga 0 +MYH11 UCSF GRCh37 16 15826454 15826454 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 56 91 0 ENST00000300036.5:c.3618G>A p.Glu1206= p.E1206= ENST00000300036 NM_002474.2 1206 gaG/gaA 0 +MYH14 UCSF GRCh37 19 50764856 50764856 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 17 14 0 ENST00000376970.2:c.2525C>T p.Ser842Phe p.S842F ENST00000376970 NM_024729.3 842 tCc/tTc 0 +MYH14 UCSF GRCh37 19 50783378 50783378 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 26 24 0 ENST00000376970.2:c.4093G>A p.Ala1365Thr p.A1365T ENST00000376970 NM_024729.3 1365 Gcc/Acc 0 +MYH2 UCSF GRCh37 17 10436690 10436690 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 36 98 0 ENST00000245503.5:c.2353G>A p.Asp785Asn p.D785N ENST00000245503 NM_017534.5 785 Gac/Aac 0 +MYO18A UCSF GRCh37 17 27434097 27434097 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 40 43 0 ENST00000527372.1:c.3441+1G>A p.X1147_splice ENST00000527372 NM_078471.3 0 +MYO18B UCSF GRCh37 22 26239836 26239836 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 43 57 0 ENST00000536101.1:c.3343C>T p.Pro1115Ser p.P1115S ENST00000536101 1115 Ccc/Tcc 0 +MYO18B UCSF GRCh37 22 26422815 26422815 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 36 25 0 ENST00000536101.1:c.6875G>A p.Gly2292Asp p.G2292D ENST00000536101 2292 gGc/gAc 0 +MYO1D UCSF GRCh37 17 31039119 31039119 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 114 77 109 0 ENST00000318217.5:c.2008G>A p.Asp670Asn p.D670N ENST00000318217 NM_015194.1 670 Gat/Aat 0 +MYO1E UCSF GRCh37 15 59548493 59548493 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 11 45 0 ENST00000288235.4:c.322G>A p.Val108Ile p.V108I ENST00000288235 NM_004998.3 108 Gtc/Atc 0 +MYO1E UCSF GRCh37 15 59515337 59515337 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 37 79 0 ENST00000288235.4:c.831G>A p.Gln277= p.Q277= ENST00000288235 NM_004998.3 277 caG/caA 0 +MYO1H UCSF GRCh37 12 109874303 109874303 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 18 58 0 ENST00000310903.5:c.2103C>T p.Ile701= p.I701= ENST00000310903 701 atC/atT 0 +MYO5A UCSF GRCh37 15 52720755 52720755 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 47 104 0 ENST00000399231.3:c.150C>T p.Tyr50= p.Y50= ENST00000399231 NM_000259.3 50 taC/taT 0 +MYO5B UCSF GRCh37 18 47363930 47363930 + synonymous_variant Silent SNP A A G snp132_rs79271359 P05_Rec Untested WXS Illumina HiSeq 82 10 54 1 ENST00000285039.7:c.5095T>C p.Leu1699= p.L1699= ENST00000285039 NM_001080467.2 1699 Ttg/Ctg 0 +MYO5B UCSF GRCh37 18 47363931 47363931 + synonymous_variant Silent SNP G G C snp132_rs77840018 P05_Rec Untested WXS Illumina HiSeq 83 10 54 1 ENST00000285039.7:c.5094C>G p.Leu1698= p.L1698= ENST00000285039 NM_001080467.2 1698 ctC/ctG 0 +MYO7A UCSF GRCh37 11 76867778 76867778 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 165 28 105 0 ENST00000409709.3:c.543G>T p.Gln181His p.Q181H ENST00000409709 NM_000260.3 181 caG/caT 0 +MYO9B UCSF GRCh37 19 17305959 17305959 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 43 20 0 ENST00000594824.1:c.3723G>A p.Gly1241= p.G1241= ENST00000594824 1241 ggG/ggA 0 +MYOC UCSF GRCh37 1 171621570 171621570 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 34 42 0 ENST00000037502.6:c.182G>A p.Cys61Tyr p.C61Y ENST00000037502 NM_000261.1 61 tGc/tAc 0 +MYOG UCSF GRCh37 1 203054970 203054970 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 58 38 0 ENST00000241651.4:c.120C>T p.Leu40= p.L40= ENST00000241651 NM_002479.5 40 ctC/ctT 0 +MYOM1 UCSF GRCh37 18 3071858 3071858 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 12 24 0 ENST00000356443.4:c.4738G>A p.Asp1580Asn p.D1580N ENST00000356443 NM_019856.1 1580 Gac/Aac 0 +MYOM1 UCSF GRCh37 18 3188757 3188757 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 31 68 0 ENST00000356443.4:c.760C>T p.Leu254= p.L254= ENST00000356443 NM_019856.1 254 Ctg/Ttg 0 +MYOM3 UCSF GRCh37 1 24398469 24398469 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 14 43 0 ENST00000374434.3:c.3003C>T p.Ile1001= p.I1001= ENST00000374434 NM_152372.3 1001 atC/atT 0 +NAA15 UCSF GRCh37 4 140262178 140262178 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 27 59 0 ENST00000296543.5:c.357C>T p.Asp119= p.D119= ENST00000296543 NM_057175.3 119 gaC/gaT 0 +NAA25 UCSF GRCh37 12 112528571 112528571 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 52 78 0 ENST00000261745.4:c.242C>T p.Ser81Leu p.S81L ENST00000261745 NM_024953.3 81 tCa/tTa 0 +NAA30 UCSF GRCh37 14 57858361 57858361 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 200 157 117 1 ENST00000556492.1:c.686G>A p.Arg229Lys p.R229K ENST00000556492 NM_001011713.2 229 aGa/aAa 0 +NAALADL1 UCSF GRCh37 11 64822020 64822020 + missense_variant Missense_Mutation SNP G G A snp132_rs35867135 P05_Rec Untested WXS Illumina HiSeq 25 19 17 0 ENST00000358658.3:c.794C>T p.Pro265Leu p.P265L ENST00000358658 NM_005468.2 265 cCc/cTc 0 +NAALADL1 UCSF GRCh37 11 64815162 64815162 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 8 8 0 ENST00000358658.3:c.1465C>T p.Arg489Trp p.R489W ENST00000358658 NM_005468.2 489 Cgg/Tgg 0 +NACC1 UCSF GRCh37 19 13246770 13246770 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 17 8 0 ENST00000292431.4:c.749G>A p.Gly250Glu p.G250E ENST00000292431 NM_052876.3 250 gGg/gAg 0 +NAGS UCSF GRCh37 17 42085896 42085896 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 154 100 130 0 ENST00000293404.3:c.1532C>T p.Ser511Phe p.S511F ENST00000293404 NM_153006.2 511 tCc/tTc 0 +NARF UCSF GRCh37 17 80422223 80422223 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 44 65 0 ENST00000309794.11:c.169G>A p.Asp57Asn p.D57N ENST00000309794 NM_031968.2 57 Gac/Aac 0 +NARFL UCSF GRCh37 16 784752 784752 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 54 45 0 ENST00000251588.2:c.559G>A p.Ala187Thr p.A187T ENST00000251588 NM_022493.1 187 Gcc/Acc 0 +NBPF3 UCSF GRCh37 1 21804669 21804669 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 201 128 274 0 ENST00000318249.5:c.1025C>T p.Pro342Leu p.P342L ENST00000318249 NM_032264.4 342 cCc/cTc 0 +NCAM1 UCSF GRCh37 11 113085228 113085228 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 40 97 0 ENST00000316851.7:c.1024G>A p.Glu342Lys p.E342K ENST00000316851 NM_181351.4 342 Gaa/Aaa 0 +NCAN UCSF GRCh37 19 19327790 19327790 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 52 78 0 ENST00000252575.6:c.28G>A p.Gly10Ser p.G10S ENST00000252575 NM_004386.2 10 Ggc/Agc 0 +NCAPH UCSF GRCh37 2 97026441 97026441 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 66 77 0 ENST00000240423.4:c.1580G>A p.Gly527Asp p.G527D ENST00000240423 NM_001281711.1 527 gGc/gAc 0 +NCOA1 UCSF GRCh37 2 24930252 24930252 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 45 73 0 ENST00000348332.3:c.1913C>T p.Thr638Ile p.T638I ENST00000348332 NM_147233.2 638 aCa/aTa 0 +NCOA5 UCSF GRCh37 20 44691394 44691394 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 43 73 0 ENST00000290231.6:c.1285C>T p.Gln429Ter p.Q429* ENST00000290231 NM_020967.2 429 Caa/Taa 0 +NCOR2 UCSF GRCh37 12 124848269 124848269 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 18 27 0 ENST00000405201.1:c.2884G>A p.Asp962Asn p.D962N ENST00000405201 962 Gac/Aac 0 +NCOR2 UCSF GRCh37 12 124819735 124819735 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 14 10 0 ENST00000405201.1:c.6357C>T p.Thr2119= p.T2119= ENST00000405201 2119 acC/acT 0 +NDNF UCSF GRCh37 4 121957629 121957629 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 73 83 0 ENST00000379692.4:c.1497C>T p.Asn499= p.N499= ENST00000379692 NM_024574.3 499 aaC/aaT 0 +NDUFB10 UCSF GRCh37 16 2011557 2011557 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 44 37 0 ENST00000268668.6:c.329G>A p.Arg110Lys p.R110K ENST00000268668 NM_004548.2 110 aGg/aAg 0 +NDUFS2 UCSF GRCh37 1 161173255 161173255 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 14 15 0 ENST00000367993.3:c.124G>A p.Glu42Lys p.E42K ENST00000367993 NM_004550.4 42 Gaa/Aaa 0 +NDUFV1 UCSF GRCh37 11 67378012 67378012 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 13 31 0 ENST00000322776.6:c.671G>T p.Arg224Leu p.R224L ENST00000322776 NM_001166102.1 224 cGc/cTc 0 +NEB UCSF GRCh37 2 152580850 152580850 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 45 77 0 ENST00000172853.10:c.536C>T p.Thr179Ile p.T179I ENST00000172853 179 aCc/aTc 0 +NEFH UCSF GRCh37 22 29881757 29881757 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 18 32 0 ENST00000310624.6:c.1129G>A p.Glu377Lys p.E377K ENST00000310624 NM_021076.3 377 Gag/Aag 0 +NET1 UCSF GRCh37 10 5498729 5498729 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 45 84 0 ENST00000355029.4:c.1563G>A p.Glu521= p.E521= ENST00000355029 NM_001047160.2 521 gaG/gaA 0 +NFATC4 UCSF GRCh37 14 24843593 24843593 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 10 34 0 ENST00000250373.4:c.1794G>A p.Val598= p.V598= ENST00000250373 NM_004554.4 598 gtG/gtA 0 +NFE2L1 UCSF GRCh37 17 46128766 46128766 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 61 49 0 ENST00000362042.3:c.286C>T p.Pro96Ser p.P96S ENST00000362042 NM_003204.2 96 Cca/Tca 0 +NFE2L1 UCSF GRCh37 17 46128657 46128657 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 74 99 0 ENST00000362042.3:c.177G>A p.Arg59= p.R59= ENST00000362042 NM_003204.2 59 agG/agA 0 +NFE2L2 UCSF GRCh37 2 178095714 178095714 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 141 84 116 0 ENST00000397062.3:c.1617G>A p.Leu539= p.L539= ENST00000397062 NM_006164.4 539 ttG/ttA 0 +NFRKB UCSF GRCh37 11 129755423 129755423 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 18 37 0 ENST00000446488.3:c.547G>A p.Glu183Lys p.E183K ENST00000446488 NM_001143835.1 183 Gag/Aag 0 +NID1 UCSF GRCh37 1 236154275 236154275 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 19 35 0 ENST00000264187.6:c.2839C>T p.Leu947Phe p.L947F ENST00000264187 NM_002508.2 947 Ctc/Ttc 0 +NID2 UCSF GRCh37 14 52508869 52508869 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 35 72 0 ENST00000216286.5:c.1779C>T p.Leu593= p.L593= ENST00000216286 NM_007361.3 593 ctC/ctT 0 +NINL UCSF GRCh37 20 25456771 25456771 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 163 75 59 0 ENST00000278886.6:c.3156G>A p.Glu1052= p.E1052= ENST00000278886 NM_025176.4 1052 gaG/gaA 0 +NIPAL3 UCSF GRCh37 1 24776049 24776049 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 30 42 0 ENST00000374399.4:c.473G>A p.Ser158Asn p.S158N ENST00000374399 NM_020448.4 158 aGt/aAt 0 +NLRP1 UCSF GRCh37 17 5425059 5425059 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 23 33 0 ENST00000572272.1:c.3568G>A p.Glu1190Lys p.E1190K ENST00000572272 1190 Gag/Aag 0 +NLRP5 UCSF GRCh37 19 56530765 56530765 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 81 154 0 ENST00000390649.3:c.622+1G>A p.X208_splice ENST00000390649 NM_153447.4 0 +NMT2 UCSF GRCh37 10 15151773 15151773 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 111 53 95 0 ENST00000378165.4:c.1404G>A p.Lys468= p.K468= ENST00000378165 NM_004808.2 468 aaG/aaA 0 +NOB1 UCSF GRCh37 16 69782883 69782883 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 23 30 0 ENST00000268802.5:c.664G>A p.Glu222Lys p.E222K ENST00000268802 NM_014062.2 222 Gag/Aag 0 +NOD1 UCSF GRCh37 7 30475661 30475661 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 27 16 0 ENST00000222823.4:c.2574G>A p.Lys858= p.K858= ENST00000222823 NM_006092.2 858 aaG/aaA 0 +NOL9 UCSF GRCh37 1 6585951 6585951 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 140 73 158 0 ENST00000377705.5:c.2072C>T p.Pro691Leu p.P691L ENST00000377705 NM_024654.4 691 cCa/cTa 0 +NOMO2 UCSF GRCh37 16 18544496 18544496 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 228 46 234 0 ENST00000381474.3:c.1226G>A p.Ser409Asn p.S409N ENST00000381474 NM_001004060.1 409 aGt/aAt 0 +NOS1 UCSF GRCh37 12 117693804 117693804 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 25 57 0 ENST00000317775.6:c.2532-2245C>T *844* ENST00000317775 NM_000620.4 0 +NOS2 UCSF GRCh37 17 26093596 26093596 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 106 73 124 0 ENST00000313735.6:c.2186C>T p.Ala729Val p.A729V ENST00000313735 NM_000625.4 729 gCc/gTc 0 +NOTCH2 UCSF GRCh37 1 120612013 120612013 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.013 P05_Rec Untested WXS Illumina HiSeq 45 9 9 0 ENST00000256646.2:c.8C>T p.Ala3Val p.A3V ENST00000256646 NM_024408.3 3 gCc/gTc 0 +NOTCH2 UCSF GRCh37 1 120612014 120612014 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.013 P05_Rec Untested WXS Illumina HiSeq 45 9 10 0 ENST00000256646.2:c.7G>T p.Ala3Ser p.A3S ENST00000256646 NM_024408.3 3 Gcc/Tcc 0 +NOTCH2 UCSF GRCh37 1 120512351 120512351 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 51 28 47 0 ENST00000256646.2:c.891G>A p.Glu297= p.E297= ENST00000256646 NM_024408.3 297 gaG/gaA 0 +NOTCH4 UCSF GRCh37 6 32168963 32168963 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 39 39 0 ENST00000375023.3:c.4070C>T p.Pro1357Leu p.P1357L ENST00000375023 NM_004557.3 1357 cCc/cTc 0 +NOXA1 UCSF GRCh37 9 140328695 140328695 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 189 60 31 0 ENST00000341349.2:c.1335G>A p.Glu445= p.E445= ENST00000341349 NM_001256067.1 445 gaG/gaA 0 +NPAT UCSF GRCh37 11 108040739 108040739 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 66 111 0 ENST00000278612.8:c.2817G>A p.Gln939= p.Q939= ENST00000278612 NM_002519.2 939 caG/caA 0 +NPHP3 UCSF GRCh37 3 132418210 132418210 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 28 7 21 0 ENST00000337331.5:c.1972C>T p.Pro658Ser p.P658S ENST00000337331 NM_153240.4 658 Cct/Tct 0 +NPHP4 UCSF GRCh37 1 5940222 5940222 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 54 81 0 ENST00000378156.4:c.2563G>A p.Ala855Thr p.A855T ENST00000378156 NM_015102.3 855 Gcc/Acc 0 +NPHS1 UCSF GRCh37 19 36333406 36333406 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 45 37 0 ENST00000378910.5:c.2381C>T p.Ser794Phe p.S794F ENST00000378910 NM_004646.3 794 tCc/tTc 0 +NQO2 UCSF GRCh37 6 3015855 3015855 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 29 14 32 0 ENST00000338130.2:c.395T>C p.Phe132Ser p.F132S ENST00000338130 132 tTc/tCc 0 +NR1H2 UCSF GRCh37 19 50882000 50882000 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 60 38 0 ENST00000253727.5:c.694G>A p.Ala232Thr p.A232T ENST00000253727 NM_007121.5 232 Gcg/Acg 0 +NR1H4 UCSF GRCh37 12 100957206 100957206 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 45 87 0 ENST00000551379.1:c.1400C>T p.Ser467Leu p.S467L ENST00000551379 467 tCa/tTa 0 +NR2C1 UCSF GRCh37 12 95456424 95456424 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 38 20 38 0 ENST00000333003.5:c.145C>G p.His49Asp p.H49D ENST00000333003 NM_003297.3 49 Cac/Gac 0 +NR2C1 UCSF GRCh37 12 95456371 95456371 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0014 P05_Rec Untested WXS Illumina HiSeq 28 17 30 0 ENST00000333003.5:c.198G>A p.Pro66= p.P66= ENST00000333003 NM_003297.3 66 ccG/ccA 0 +NRG1 UCSF GRCh37 8 32453351 32453351 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 44 81 0 ENST00000405005.3:c.106C>T p.Pro36Ser p.P36S ENST00000405005 36 Cct/Tct 0 +NRL UCSF GRCh37 14 24551985 24551985 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 21 23 0 ENST00000396997.1:c.73C>T p.Arg25Trp p.R25W ENST00000396997 25 Cgg/Tgg 0 +NRSN1 UCSF GRCh37 6 24145818 24145818 + downstream_gene_variant 3'Flank SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 82 54 95 0 ENST00000378478 0 +NRXN3 UCSF GRCh37 14 79117661 79117661 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 77 145 0 ENST00000554719.1:c.94C>T p.Leu32Phe p.L32F ENST00000554719 NM_004796.5 32 Ctt/Ttt 0 +NSMAF UCSF GRCh37 8 59496711 59496711 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 37 97 0 ENST00000038176.3:c.2708C>T p.Thr903Ile p.T903I ENST00000038176 NM_003580.3 903 aCa/aTa 0 +NTRK3 UCSF GRCh37 15 88679226 88679226 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 41 73 0 ENST00000360948.2:c.811G>A p.Val271Met p.V271M ENST00000360948 NM_001012338.2 271 Gtg/Atg 0 +NUDC UCSF GRCh37 1 27272131 27272131 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 36 110 0 ENST00000321265.5:c.898G>A p.Gly300Arg p.G300R ENST00000321265 NM_006600.3 300 Ggg/Agg 0 +NUDCD2 UCSF GRCh37 5 162886898 162886898 + synonymous_variant Silent SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 15 29 1 ENST00000302764.4:c.159G>T p.Ala53= p.A53= ENST00000302764 NM_145266.4 53 gcG/gcT 0 +NUDCD3 UCSF GRCh37 7 44467172 44467172 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 19 51 0 ENST00000355451.7:c.640C>T p.Gln214Ter p.Q214* ENST00000355451 NM_015332.3 214 Cag/Tag 0 +NUMB UCSF GRCh37 14 73750891 73750891 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 59 92 0 ENST00000355058.3:c.847C>T p.Leu283Phe p.L283F ENST00000355058 283 Ctt/Ttt 0 +NUP188 UCSF GRCh37 9 131735512 131735512 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 17 29 0 ENST00000372577.2:c.1187C>T p.Thr396Ile p.T396I ENST00000372577 NM_015354.2 396 aCc/aTc 0 +NUP210 UCSF GRCh37 3 13393458 13393458 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 19 56 0 ENST00000254508.5:c.2756G>A p.Gly919Asp p.G919D ENST00000254508 NM_024923.3 919 gGc/gAc 0 +NUP210 UCSF GRCh37 3 13401975 13401975 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 12 22 0 ENST00000254508.5:c.1949C>T p.Ser650Phe p.S650F ENST00000254508 NM_024923.3 650 tCt/tTt 0 +NUP93 UCSF GRCh37 16 56878490 56878490 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 18 40 0 ENST00000308159.5:c.2429G>A p.Arg810Lys p.R810K ENST00000308159 NM_014669.4 810 aGg/aAg 0 +NUPL1 UCSF GRCh37 13 25905498 25905498 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 41 58 0 ENST00000381736.3:c.1237C>T p.Leu413= p.L413= ENST00000381736 NM_014089.3 413 Ctg/Ttg 0 +NXF3 UCSF GRCh37 X 102337686 102337686 + splice_donor_variant Splice_Site SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 58 34 112 0 ENST00000395065.3:c.780+2T>G p.X260_splice ENST00000395065 NM_022052.1 0 +OAS1 UCSF GRCh37 12 113349034 113349034 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0015 P05_Rec Untested WXS Illumina HiSeq 70 29 75 0 ENST00000202917.5:c.648C>T p.Tyr216= p.Y216= ENST00000202917 NM_016816.2 216 taC/taT 0 +OAS2 UCSF GRCh37 12 113436196 113436196 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 149 43 109 0 ENST00000342315.4:c.989C>T p.Ala330Val p.A330V ENST00000342315 NM_016817.2 330 gCa/gTa 0 +OASL UCSF GRCh37 12 121458523 121458523 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 38 68 0 ENST00000257570.5:c.1386G>A p.Gln462= p.Q462= ENST00000257570 NM_003733.3 462 caG/caA 0 +OBSCN UCSF GRCh37 1 228476566 228476566 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 57 67 0 ENST00000422127.1:c.10316C>T p.Thr3439Ile p.T3439I ENST00000422127 NM_001098623.2 3439 aCc/aTc 0 +OBSCN UCSF GRCh37 1 228403510 228403510 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 24 23 0 ENST00000422127.1:c.2075G>A p.Ser692Asn p.S692N ENST00000422127 NM_001098623.2 692 aGc/aAc 0 +OBSCN UCSF GRCh37 1 228497197 228497197 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 44 75 0 ENST00000422127.1:c.12949G>A p.Asp4317Asn p.D4317N ENST00000422127 NM_001098623.2 4317 Gat/Aat 0 +OBSCN UCSF GRCh37 1 228481893 228481893 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 155 102 130 0 ENST00000422127.1:c.11172G>A p.Glu3724= p.E3724= ENST00000422127 NM_001098623.2 3724 gaG/gaA 0 +ODF2 UCSF GRCh37 9 131262353 131262353 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 40 58 0 ENST00000434106.3:c.2309G>A p.Arg770His p.R770H ENST00000434106 NM_153433.1 770 cGc/cAc 0 +ODZ2 UCSF GRCh37 5 167420045 167420045 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0034 P05_Rec Untested WXS Illumina HiSeq 37 60 98 0 ENST00000518659.1:c.1044G>A p.Pro348= p.P348= ENST00000518659 NM_001122679.1 348 ccG/ccA 0 +ODZ4 UCSF GRCh37 11 78413374 78413374 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 131 117 150 0 ENST00000278550.7:c.4284G>A p.Val1428= p.V1428= ENST00000278550 NM_001098816.2 1428 gtG/gtA 0 +OGFR UCSF GRCh37 20 61444600 61444600 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.039,1000g2011may_all_0.0976,snp132_rs6122313 P05_Rec Untested WXS Illumina HiSeq 25 7 10 0 ENST00000290291.6:c.1633C>A p.Arg545Ser p.R545S ENST00000290291 NM_007346.2 545 Cgc/Agc 0 +OLFM1 UCSF GRCh37 9 137987827 137987827 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 106 35 44 0 ENST00000371793.3:c.418G>A p.Glu140Lys p.E140K ENST00000371793 NM_001282611.1 140 Gag/Aag 0 +OLFM4 UCSF GRCh37 13 53624333 53624333 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 66 115 0 ENST00000219022.2:c.960G>A p.Glu320= p.E320= ENST00000219022 NM_006418.4 320 gaG/gaA 0 +OPRM1 UCSF GRCh37 6 154360645 154360645 + 5_prime_UTR_variant 5'UTR SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 13 14 0 ENST00000330432.7:c.-35C>T *12* ENST00000330432 NM_000914.3 0 +OPTN UCSF GRCh37 10 13169851 13169851 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 45 92 0 ENST00000263036.5:c.1349C>T p.Thr450Ile p.T450I ENST00000263036 450 aCc/aTc 0 +OR10AG1 UCSF GRCh37 11 55735468 55735468 + missense_variant Missense_Mutation SNP G G A snp132_rs77704611 P05_Rec Untested WXS Illumina HiSeq 40 35 61 0 ENST00000312345.2:c.472C>T p.Pro158Ser p.P158S ENST00000312345 NM_001005491.1 158 Ccc/Tcc 0 +OR10G9 UCSF GRCh37 11 123894533 123894533 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 60 114 0 ENST00000375024.1:c.814G>A p.Ala272Thr p.A272T ENST00000375024 NM_001001953.1 272 Gcc/Acc 0 +OR10J3 UCSF GRCh37 1 159283715 159283715 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 63 105 0 ENST00000332217.5:c.735C>T p.His245= p.H245= ENST00000332217 NM_001004467.1 245 caC/caT 0 +OR10T2 UCSF GRCh37 1 158368825 158368825 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 36 114 0 ENST00000334438.1:c.432G>A p.Glu144= p.E144= ENST00000334438 NM_001004475.1 144 gaG/gaA 0 +OR1E2 UCSF GRCh37 17 3336691 3336691 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 43 30 55 0 ENST00000248384.1:c.445C>G p.Leu149Val p.L149V ENST00000248384 NM_003554.1 149 Ctc/Gtc 0 +OR1L8 UCSF GRCh37 9 125329947 125329947 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 25 80 0 ENST00000304865.2:c.810G>A p.Lys270= p.K270= ENST00000304865 NM_001004454.1 270 aaG/aaA 0 +OR2A25 UCSF GRCh37 7 143771842 143771842 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 223 80 170 0 ENST00000408898.2:c.530T>G p.Phe177Cys p.F177C ENST00000408898 NM_001004488.1 177 tTc/tGc 0 +OR2C1 UCSF GRCh37 16 3406567 3406567 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 46 74 0 ENST00000304936.2:c.627C>T p.Val209= p.V209= ENST00000304936 NM_012368.2 209 gtC/gtT 0 +OR56A5 UCSF GRCh37 11 5989353 5989353 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 66 179 0 ENST00000532411.1:n.372C>T *124* ENST00000532411 0 +OR5V1 UCSF GRCh37 6 29323969 29323969 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 29 42 0 ENST00000377154.1:c.4G>A p.Glu2Lys p.E2K ENST00000377154 2 Gaa/Aaa 0 +OR6V1 UCSF GRCh37 7 142749760 142749760 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 156 55 107 0 ENST00000418316.1:c.323C>T p.Thr108Ile p.T108I ENST00000418316 NM_001001667.1 108 aCc/aTc 0 +OR7A5 UCSF GRCh37 19 14938928 14938928 + synonymous_variant Silent SNP G G A snp132_rs76014757 P05_Rec Untested WXS Illumina HiSeq 133 83 141 0 ENST00000322301.3:c.126C>T p.Asn42= p.N42= ENST00000322301 42 aaC/aaT 0 +OR7G1 UCSF GRCh37 19 9226037 9226037 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 64 171 0 ENST00000541538.1:c.403C>T p.Leu135Phe p.L135F ENST00000541538 NM_001005192.2 135 Ctc/Ttc 0 +OR8H1 UCSF GRCh37 11 56057643 56057643 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 77 133 0 ENST00000313022.2:c.896C>T p.Ala299Val p.A299V ENST00000313022 NM_001005199.1 299 gCt/gTt 0 +OSBPL10 UCSF GRCh37 3 31725542 31725542 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 31 37 0 ENST00000396556.2:c.1310C>T p.Ala437Val p.A437V ENST00000396556 NM_017784.4 437 gCg/gTg 0 +OSBPL11 UCSF GRCh37 3 125271277 125271277 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 45 68 0 ENST00000296220.5:c.1402G>A p.Val468Ile p.V468I ENST00000296220 NM_022776.4 468 Gta/Ata 0 +OSBPL5 UCSF GRCh37 11 3111847 3111847 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 17 27 16 0 ENST00000263650.7:c.2339C>T p.Ser780Phe p.S780F ENST00000263650 NM_020896.3 780 tCc/tTc 0 +OTUD4 UCSF GRCh37 4 146077122 146077122 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 19 28 38 0 ENST00000447906.2:c.656A>C p.Asp219Ala p.D219A ENST00000447906 219 gAt/gCt 0 +OTUD7A UCSF GRCh37 15 31862393 31862393 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 36 36 0 ENST00000307050.4:c.159C>T p.Asn53= p.N53= ENST00000307050 NM_130901.1 53 aaC/aaT 0 +OXA1L UCSF GRCh37 14 23235862 23235862 + synonymous_variant Silent SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 128 82 93 0 ENST00000285848.5:c.132T>C p.Gly44= p.G44= ENST00000285848 NM_005015.3 44 ggT/ggC 0 +PADI2 UCSF GRCh37 1 17413169 17413169 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 35 45 0 ENST00000375486.4:c.681C>T p.Ile227= p.I227= ENST00000375486 NM_007365.2 227 atC/atT 0 +PADI6 UCSF GRCh37 1 17727751 17727751 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 34 62 0 ENST00000434762.2:n.1953G>A *651* ENST00000434762 0 +PALMD UCSF GRCh37 1 100155175 100155175 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 23 61 0 ENST00000263174.4:c.1359G>A p.Glu453= p.E453= ENST00000263174 NM_017734.4 453 gaG/gaA 0 +PANK1 UCSF GRCh37 10 91348448 91348448 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 37 56 0 ENST00000307534.4:c.1698G>A p.Trp566Ter p.W566* ENST00000307534 NM_148977.2 566 tgG/tgA 0 +PANK4 UCSF GRCh37 1 2452632 2452632 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 156 75 73 0 ENST00000378466.3:c.330C>T p.Asp110= p.D110= ENST00000378466 NM_018216.1 110 gaC/gaT 0 +PAPLN UCSF GRCh37 14 73733540 73733540 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 9 9 0 ENST00000554301.1:c.3500+1G>A p.X1167_splice ENST00000554301 0 +PAPPA2 UCSF GRCh37 1 176661375 176661375 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 76 121 0 ENST00000367662.3:c.2545C>T p.Pro849Ser p.P849S ENST00000367662 NM_020318.2 849 Cca/Tca 0 +PAPPA2 UCSF GRCh37 1 176708825 176708825 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 43 26 42 0 ENST00000367662.3:c.3862G>C p.Val1288Leu p.V1288L ENST00000367662 NM_020318.2 1288 Gtt/Ctt 0 +PARP1 UCSF GRCh37 1 226579986 226579986 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 154 92 143 0 ENST00000366794.5:c.316G>A p.Ala106Thr p.A106T ENST00000366794 NM_001618.3 106 Gca/Aca 0 +PARVG UCSF GRCh37 22 44585128 44585128 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 33 12 0 ENST00000422871.1:c.382G>A p.Val128Met p.V128M ENST00000422871 NM_001137605.2 128 Gtg/Atg 0 +PAXIP1 UCSF GRCh37 7 154755379 154755379 + splice_donor_variant Splice_Site SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 48 15 39 0 ENST00000397192.1:c.1989+2T>C p.X663_splice ENST00000397192 NM_007349.3 0 +PCDH15 UCSF GRCh37 10 56138586 56138586 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 64 109 0 ENST00000320301.6:c.274C>T p.Gln92Ter p.Q92* ENST00000320301 NM_033056.3 92 Caa/Taa 0 +PCDH20 UCSF GRCh37 13 61986537 61986537 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 50 89 0 ENST00000409186.1:c.1695G>A p.Glu565= p.E565= ENST00000409186 565 gaG/gaA 0 +PCDHA13 UCSF GRCh37 5 140263138 140263138 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 168 103 0 ENST00000289272.2:c.1285G>A p.Asp429Asn p.D429N ENST00000289272 NM_018904.2 429 Gac/Aac 0 +PCDHA13 UCSF GRCh37 5 140263738 140263738 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 126 51 0 ENST00000289272.2:c.1885G>A p.Gly629Ser p.G629S ENST00000289272 NM_018904.2 629 Ggc/Agc 0 +PCDHB15 UCSF GRCh37 5 140626910 140626910 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 95 44 0 ENST00000231173.3:c.1764G>A p.Lys588= p.K588= ENST00000231173 NM_018935.2 588 aaG/aaA 0 +PCDHB16 UCSF GRCh37 5 140563711 140563711 + missense_variant Missense_Mutation SNP A A C 1000g2011may_all_0.0597,snp132_rs17844652 P05_Rec Untested WXS Illumina HiSeq 41 8 49 1 ENST00000361016.2:c.1577A>C p.Glu526Ala p.E526A ENST00000361016 NM_020957.1 526 gAg/gCg 0 +PCDHB16 UCSF GRCh37 5 140563712 140563712 + missense_variant Missense_Mutation SNP G G T 1000g2011may_all_0.0455,snp132_rs17844653 P05_Rec Untested WXS Illumina HiSeq 41 8 52 1 ENST00000361016.2:c.1578G>T p.Glu526Asp p.E526D ENST00000361016 NM_020957.1 526 gaG/gaT 0 +PCDHGB2 UCSF GRCh37 5 140739819 140739819 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 40 68 0 ENST00000522605.1:c.117G>A p.Glu39= p.E39= ENST00000522605 NM_018923.2 39 gaG/gaA 0 +PCF11 UCSF GRCh37 11 82877001 82877001 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 147 88 97 0 ENST00000298281.4:c.1062G>A p.Lys354= p.K354= ENST00000298281 NM_015885.3 354 aaG/aaA 0 +PCLO UCSF GRCh37 7 82579344 82579344 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 248 87 181 0 ENST00000333891.9:c.10560G>A p.Thr3520= p.T3520= ENST00000333891 NM_033026.5 3520 acG/acA 0 +PCNT UCSF GRCh37 21 47786908 47786908 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 218 132 125 0 ENST00000359568.5:c.3019C>T p.Leu1007Phe p.L1007F ENST00000359568 NM_006031.5 1007 Ctt/Ttt 0 +PCNT UCSF GRCh37 21 47862463 47862463 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 31 15 0 ENST00000359568.5:c.9677C>T p.Ala3226Val p.A3226V ENST00000359568 NM_006031.5 3226 gCa/gTa 0 +PCNT UCSF GRCh37 21 47860958 47860958 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014,snp132_rs78524660 P05_Rec Untested WXS Illumina HiSeq 80 40 49 0 ENST00000359568.5:c.9584G>A p.Arg3195Lys p.R3195K ENST00000359568 NM_006031.5 3195 aGg/aAg 0 +PCNXL2 UCSF GRCh37 1 233134083 233134083 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 30 37 0 ENST00000258229.9:c.5705G>A p.Gly1902Asp p.G1902D ENST00000258229 NM_014801.3 1902 gGt/gAt 0 +PCOLCE UCSF GRCh37 7 100205689 100205689 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 28 57 0 ENST00000223061.5:c.1313C>T p.Pro438Leu p.P438L ENST00000223061 NM_002593.3 438 cCc/cTc 0 +PCOLCE2 UCSF GRCh37 3 142606618 142606618 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 29 38 0 ENST00000295992.3:c.85C>T p.Pro29Ser p.P29S ENST00000295992 NM_013363.3 29 Cct/Tct 0 +PCSK9 UCSF GRCh37 1 55524305 55524305 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 19 23 0 ENST00000302118.5:c.1488G>A p.Arg496= p.R496= ENST00000302118 NM_174936.3 496 cgG/cgA 0 +PDCD11 UCSF GRCh37 10 105178277 105178277 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 44 57 0 ENST00000369797.3:c.1992C>T p.Leu664= p.L664= ENST00000369797 NM_014976.1 664 ctC/ctT 0 +PDE1C UCSF GRCh37 7 31912975 31912975 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 16 37 0 ENST00000321453.7:c.539G>A p.Ser180Asn p.S180N ENST00000321453 NM_001191059.1 180 aGt/aAt 0 +PDE4B UCSF GRCh37 1 66384414 66384414 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 38 69 0 ENST00000329654.4:c.177G>A p.Gln59= p.Q59= ENST00000329654 NM_001037341.1 59 caG/caA 0 +PDE4DIP UCSF GRCh37 1 144852379 144852379 + 3_prime_UTR_variant 3'UTR SNP G G T 1000g2010nov_all_0.022,1000g2011may_all_0.05769,snp132_rs113954821 P05_Rec Untested WXS Illumina HiSeq 61 10 35 1 ENST00000369354.3:c.*79C>A *27* ENST00000369354 0 +PDGFRA UCSF GRCh37 4 55156572 55156572 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 179 56 89 0 ENST00000257290.5:c.2973C>T p.Val991= p.V991= ENST00000257290 NM_006206.4 991 gtC/gtT 0 +PDK4 UCSF GRCh37 7 95222149 95222149 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 132 49 100 0 ENST00000005178.5:c.452C>T p.Thr151Ile p.T151I ENST00000005178 NM_002612.3 151 aCc/aTc 0 +PDS5A UCSF GRCh37 4 39904041 39904041 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 37 74 0 ENST00000303538.8:c.1425C>T p.Pro475= p.P475= ENST00000303538 NM_001100399.1 475 ccC/ccT 0 +PDZD7 UCSF GRCh37 10 102770636 102770636 + downstream_gene_variant 3'Flank SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 5 11 9 0 ENST00000370220 0 +PEG10 UCSF GRCh37 7 94293624 94293624 + synonymous_variant Silent SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 171 35 39 0 ENST00000482108.1:c.756G>C p.Ser252= p.S252= ENST00000482108 NM_001172437.1 252 tcG/tcC 0 +PER1 UCSF GRCh37 17 8051124 8051124 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 18 17 0 ENST00000317276.4:c.1256C>T p.Pro419Leu p.P419L ENST00000317276 NM_002616.2 419 cCc/cTc 0 +PER3 UCSF GRCh37 1 7869993 7869993 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 32 26 0 ENST00000361923.2:c.1280G>A p.Gly427Glu p.G427E ENST00000361923 NM_016831.1 427 gGg/gAg 0 +PEX1 UCSF GRCh37 7 92131386 92131386 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 231 92 121 0 ENST00000248633.4:c.2234G>A p.Arg745Lys p.R745K ENST00000248633 NM_000466.2 745 aGa/aAa 0 +PFKFB4 UCSF GRCh37 3 48587361 48587361 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 21 49 0 ENST00000232375.3:c.247G>A p.Val83Ile p.V83I ENST00000232375 NM_004567.2 83 Gtc/Atc 0 +PGLYRP2 UCSF GRCh37 19 15587253 15587253 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 35 50 0 ENST00000340880.4:c.228C>T p.Leu76= p.L76= ENST00000340880 NM_052890.3 76 ctC/ctT 0 +PGS1 UCSF GRCh37 17 76399899 76399899 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 60 76 0 ENST00000262764.6:c.1131G>A p.Glu377= p.E377= ENST00000262764 NM_024419.3 377 gaG/gaA 0 +PHACTR1 UCSF GRCh37 6 13206076 13206076 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 134 57 87 0 ENST00000332995.7:c.694C>T p.Leu232= p.L232= ENST00000332995 232 Ctg/Ttg 0 +PHC3 UCSF GRCh37 3 169896720 169896720 + 5_prime_UTR_variant 5'UTR SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 192 64 182 0 ENST00000494943.1:c.-16G>A *6* ENST00000494943 0 +PHF2 UCSF GRCh37 9 96418217 96418217 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 9 11 0 ENST00000359246.4:c.954C>T p.Gly318= p.G318= ENST00000359246 NM_005392.3 318 ggC/ggT 0 +PHF20 UCSF GRCh37 20 34487567 34487567 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 7 40 0 ENST00000374012.3:c.1558C>T p.Pro520Ser p.P520S ENST00000374012 520 Cca/Tca 0 +PHLDB1 UCSF GRCh37 11 118514893 118514893 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 16 8 0 ENST00000361417.2:c.3121+1G>A p.X1041_splice ENST00000361417 NM_015157.3 0 +PHLPP2 UCSF GRCh37 16 71683592 71683592 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 181 69 52 0 ENST00000568954.1:c.3173C>T p.Thr1058Ile p.T1058I ENST00000568954 1058 aCc/aTc 0 +PI15 UCSF GRCh37 8 75757721 75757721 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 53 102 0 ENST00000260113.2:c.630C>T p.Asn210= p.N210= ENST00000260113 NM_015886.3 210 aaC/aaT 0 +PI4KA UCSF GRCh37 22 21159316 21159316 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 62 87 0 ENST00000255882.6:c.1306C>T p.Gln436Ter p.Q436* ENST00000255882 NM_058004.3 436 Cag/Tag 0 +PI4KA UCSF GRCh37 22 21101870 21101870 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 28 52 0 ENST00000255882.6:c.3363+1G>A p.X1121_splice ENST00000255882 NM_058004.3 0 +PI4KA UCSF GRCh37 22 21081530 21081530 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 21 24 0 ENST00000255882.6:c.4929G>A p.Arg1643= p.R1643= ENST00000255882 NM_058004.3 1643 cgG/cgA 0 +PIEZO2 UCSF GRCh37 18 10784940 10784940 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 39 83 0 ENST00000503781.3:c.2334C>T p.Gly778= p.G778= ENST00000503781 NM_022068.2 778 ggC/ggT 0 +PIGQ UCSF GRCh37 16 633059 633059 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 115 79 39 0 ENST00000026218.5:c.1708C>T p.Pro570Ser p.P570S ENST00000026218 NM_148920.2 570 Cca/Tca 0 +PIGR UCSF GRCh37 1 207107863 207107863 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 29 42 0 ENST00000356495.4:c.1607G>A p.Arg536Lys p.R536K ENST00000356495 NM_002644.3 536 aGg/aAg 0 +PIK3CB UCSF GRCh37 3 138433487 138433487 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 80 99 0 ENST00000289153.2:c.1125G>A p.Gly375= p.G375= ENST00000289153 NM_006219.2 375 ggG/ggA 0 +PIK3IP1 UCSF GRCh37 22 31688292 31688292 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 26 67 0 ENST00000215912.5:c.39C>T p.Asn13= p.N13= ENST00000215912 NM_052880.4 13 aaC/aaT 0 +PIK3R1 UCSF GRCh37 5 67591123 67591123 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 55 110 0 ENST00000521381.1:c.1716G>A p.Gln572= p.Q572= ENST00000521381 NM_181523.2 572 caG/caA 0 +PIN4 UCSF GRCh37 X 71401585 71401585 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 10 19 0 ENST00000373669.2:c.25G>A p.Gly9Arg p.G9R ENST00000373669 NM_006223.3 9 Ggg/Agg 0 +PION UCSF GRCh37 7 76984937 76984937 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 29 71 0 ENST00000257626.7:c.1055G>A p.Gly352Asp p.G352D ENST00000257626 NM_017439.3 352 gGt/gAt 0 +PIP5KL1 UCSF GRCh37 9 130692077 130692077 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 6 9 0 ENST00000388747.4:c.118C>T p.Arg40Cys p.R40C ENST00000388747 NM_001135219.1 40 Cgc/Tgc 0 +PITPNA UCSF GRCh37 17 1438748 1438748 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 56 115 0 ENST00000313486.7:c.521G>A p.Gly174Asp p.G174D ENST00000313486 NM_006224.3 174 gGc/gAc 0 +PIWIL1 UCSF GRCh37 12 130839435 130839435 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 104 30 114 0 ENST00000245255.3:c.1174C>T p.Leu392= p.L392= ENST00000245255 NM_004764.4 392 Cta/Tta 0 +PIWIL3 UCSF GRCh37 22 25115836 25115836 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 11 48 0 ENST00000332271.5:c.2411C>T p.Ser804Phe p.S804F ENST00000332271 NM_001255975.1 804 tCt/tTt 0 +PKD1 UCSF GRCh37 16 2155909 2155909 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 14 12 0 ENST00000262304.4:c.7820A>T p.His2607Leu p.H2607L ENST00000262304 NM_001009944.2 2607 cAc/cTc 0 +PKD1 UCSF GRCh37 16 2160968 2160968 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 54 26 0 ENST00000262304.4:c.4200G>A p.Leu1400= p.L1400= ENST00000262304 NM_001009944.2 1400 ctG/ctA 0 +PKD1L1 UCSF GRCh37 7 47920325 47920325 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 17 61 0 ENST00000289672.2:c.3520+1G>A p.X1174_splice ENST00000289672 NM_138295.3 0 +PKD1L1 UCSF GRCh37 7 47874767 47874767 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 39 14 16 0 ENST00000289672.2:c.6018G>A p.Gly2006= p.G2006= ENST00000289672 NM_138295.3 2006 ggG/ggA 0 +PKD1L1 UCSF GRCh37 7 47968988 47968988 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 141 54 100 0 ENST00000289672.2:c.873C>T p.Asn291= p.N291= ENST00000289672 NM_138295.3 291 aaC/aaT 0 +PKD1L3 UCSF GRCh37 16 71976564 71976564 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 154 46 112 0 ENST00000534738.1:n.4219G>A *1407* ENST00000534738 0 +PKDREJ UCSF GRCh37 22 46657443 46657443 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 35 69 0 ENST00000253255.5:c.1777C>T p.Pro593Ser p.P593S ENST00000253255 NM_006071.1 593 Cct/Tct 0 +PKP1 UCSF GRCh37 1 201293710 201293710 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 12 27 0 ENST00000263946.3:c.1897+1G>A p.X633_splice ENST00000263946 NM_000299.3 0 +PLA1A UCSF GRCh37 3 119316765 119316765 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 4 13 0 ENST00000273371.4:c.5C>T p.Pro2Leu p.P2L ENST00000273371 NM_015900.3 2 cCc/cTc 0 +PLA2R1 UCSF GRCh37 2 160801461 160801461 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 45 77 0 ENST00000283243.7:c.4100C>T p.Ser1367Phe p.S1367F ENST00000283243 NM_001195641.1 1367 tCc/tTc 0 +PLA2R1 UCSF GRCh37 2 160806163 160806163 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 42 71 0 ENST00000283243.7:c.3665C>T p.Ala1222Val p.A1222V ENST00000283243 NM_001195641.1 1222 gCc/gTc 0 +PLCE1 UCSF GRCh37 10 96033478 96033478 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 26 69 0 ENST00000260766.3:c.4665+1G>A p.X1555_splice ENST00000260766 NM_016341.3 0 +PLCG1 UCSF GRCh37 20 39792412 39792412 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 70 102 0 ENST00000373271.1:c.949G>A p.Val317Ile p.V317I ENST00000373271 NM_182811.1 317 Gta/Ata 0 +PLCG1 UCSF GRCh37 20 39798167 39798167 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 46 62 0 ENST00000373271.1:c.2650+1G>A p.X884_splice ENST00000373271 NM_182811.1 0 +PLCH1 UCSF GRCh37 3 155271904 155271904 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 50 15 62 0 ENST00000340059.7:c.1115T>G p.Val372Gly p.V372G ENST00000340059 NM_001130960.1 372 gTt/gGt 0 +PLCL1 UCSF GRCh37 2 198950221 198950221 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 55 45 59 0 ENST00000428675.1:c.1980G>A p.Trp660Ter p.W660* ENST00000428675 NM_006226.3 660 tgG/tgA 0 +PLCL2 UCSF GRCh37 3 17051631 17051631 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 75 77 0 ENST00000418129.2:c.415G>A p.Asp139Asn p.D139N ENST00000418129 NM_001144382.1 139 Gat/Aat 0 +PLCL2 UCSF GRCh37 3 17053574 17053574 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 153 32 73 0 ENST00000418129.2:c.2358G>A p.Trp786Ter p.W786* ENST00000418129 NM_001144382.1 786 tgG/tgA 0 +PLD2 UCSF GRCh37 17 4712455 4712455 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 43 57 0 ENST00000263088.6:c.444C>T p.Pro148= p.P148= ENST00000263088 NM_001243108.1 148 ccC/ccT 0 +PLEKHG1 UCSF GRCh37 6 151152103 151152103 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 43 92 0 ENST00000358517.2:c.1856C>T p.Pro619Leu p.P619L ENST00000358517 619 cCt/cTt 0 +PLEKHH3 UCSF GRCh37 17 40822682 40822682 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 39 28 0 ENST00000591022.1:c.1463C>T p.Ser488Phe p.S488F ENST00000591022 NM_024927.4 488 tCc/tTc 0 +PLEKHM1 UCSF GRCh37 17 43530914 43530914 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 36 77 0 ENST00000430334.3:c.2304G>A p.Trp768Ter p.W768* ENST00000430334 NM_014798.2 768 tgG/tgA 0 +PLEKHM3 UCSF GRCh37 2 208842115 208842115 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 48 102 0 ENST00000427836.2:c.806G>A p.Gly269Asp p.G269D ENST00000427836 NM_001080475.2 269 gGc/gAc 0 +PLEKHM3 UCSF GRCh37 2 208693094 208693094 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 55 96 0 ENST00000427836.2:c.2235G>A p.Glu745= p.E745= ENST00000427836 NM_001080475.2 745 gaG/gaA 0 +PLEKHN1 UCSF GRCh37 1 909744 909744 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 34 30 0 ENST00000379409.2:c.1858G>A p.Asp620Asn p.D620N ENST00000379409 620 Gat/Aat 0 +PLEKHO2 UCSF GRCh37 15 65140927 65140927 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 50 75 0 ENST00000323544.4:c.148G>A p.Val50Ile p.V50I ENST00000323544 NM_025201.4 50 Gtc/Atc 0 +PLG UCSF GRCh37 6 161128732 161128732 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 150 66 177 0 ENST00000308192.9:c.186G>A p.Arg62= p.R62= ENST00000308192 NM_000301.3 62 agG/agA 0 +PLIN4 UCSF GRCh37 19 4511827 4511827 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 682 132 341 0 ENST00000301286.3:c.2103C>T p.Val701= p.V701= ENST00000301286 NM_001080400.1 701 gtC/gtT 0 +PLK1S1 UCSF GRCh37 20 21209665 21209665 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 53 89 0 ENST00000457464.1:n.1292G>A *431* ENST00000457464 0 +PLOD2 UCSF GRCh37 3 145788564 145788564 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 41 12 35 0 ENST00000360060.3:c.2154T>G p.His718Gln p.H718Q ENST00000360060 NM_000935.2 718 caT/caG 0 +PLP1 UCSF GRCh37 X 103042780 103042780 + stop_gained Nonsense_Mutation SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 65 78 0 ENST00000418604.1:c.507C>A p.Cys169Ter p.C169* ENST00000418604 NM_001128834.1 169 tgC/tgA 0 +PLS3 UCSF GRCh37 X 114882259 114882259 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 61 98 1 ENST00000355899.3:c.1682C>T p.Ala561Val p.A561V ENST00000355899 NM_005032.5 561 gCc/gTc 0 +PLSCR4 UCSF GRCh37 3 145924354 145924354 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 31 80 0 ENST00000354952.2:c.313C>T p.Pro105Ser p.P105S ENST00000354952 NM_020353.2 105 Cct/Tct 0 +PLXNB2 UCSF GRCh37 22 50724666 50724666 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0034 P05_Rec Untested WXS Illumina HiSeq 33 68 50 0 ENST00000359337.4:c.1813C>T p.Leu605Phe p.L605F ENST00000359337 NM_012401.3 605 Ctc/Ttc 0 +PMAIP1 UCSF GRCh37 18 57569967 57569967 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 53 85 0 ENST00000316660.6:c.147C>T p.Leu49= p.L49= ENST00000316660 NM_021127.2 49 ctC/ctT 0 +PMEL UCSF GRCh37 12 56348011 56348011 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 37 62 0 ENST00000548493.1:c.1973G>A p.Gly658Glu p.G658E ENST00000548493 658 gGg/gAg 0 +PNO1 UCSF GRCh37 2 68385661 68385661 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 41 62 0 ENST00000263657.2:c.357G>A p.Arg119= p.R119= ENST00000263657 NM_020143.2 119 agG/agA 0 +PNPLA6 UCSF GRCh37 19 7623800 7623800 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 30 14 0 ENST00000414982.3:c.3492G>A p.Glu1164= p.E1164= ENST00000414982 NM_001166111.1 1164 gaG/gaA 0 +PNPLA7 UCSF GRCh37 9 140416145 140416145 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 79 32 43 0 ENST00000277531.4:c.825G>A p.Arg275= p.R275= ENST00000277531 NM_152286.3 275 agG/agA 0 +PNPLA8 UCSF GRCh37 7 108155515 108155515 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 183 53 35 0 ENST00000257694.8:c.421G>A p.Asp141Asn p.D141N ENST00000257694 NM_001256007.1 141 Gat/Aat 0 +PNPT1 UCSF GRCh37 2 55912183 55912183 + missense_variant,splice_region_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 25 41 0 ENST00000415374.1:c.298G>A p.Val100Ile p.V100I ENST00000415374 100 Gtt/Att 0 +PODN UCSF GRCh37 1 53542970 53542970 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 91 67 0 ENST00000312553.5:c.834C>T p.Arg278= p.R278= ENST00000312553 NM_001199081.1 278 cgC/cgT 0 +POF1B UCSF GRCh37 X 84600880 84600880 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 58 119 0 ENST00000262753.4:c.709C>T p.Gln237Ter p.Q237* ENST00000262753 NM_024921.3 237 Cag/Tag 0 +POFUT2 UCSF GRCh37 21 46705667 46705667 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 36 85 0 ENST00000349485.5:c.308C>T p.Pro103Leu p.P103L ENST00000349485 NM_133635.4 103 cCc/cTc 0 +POGZ UCSF GRCh37 1 151384149 151384149 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 19 74 0 ENST00000271715.2:c.1878G>A p.Lys626= p.K626= ENST00000271715 NM_015100.3 626 aaG/aaA 0 +POLD2 UCSF GRCh37 7 44157619 44157619 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 24 48 0 ENST00000406581.2:c.265G>A p.Glu89Lys p.E89K ENST00000406581 NM_001256879.1 89 Gag/Aag 0 +POLD2 UCSF GRCh37 7 44154928 44154928 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 126 33 56 0 ENST00000406581.2:c.1215C>T p.Gly405= p.G405= ENST00000406581 NM_001256879.1 405 ggC/ggT 0 +POLH UCSF GRCh37 6 43581825 43581825 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 52 98 0 ENST00000372236.4:c.1673C>T p.Ser558Phe p.S558F ENST00000372236 NM_006502.2 558 tCc/tTc 0 +POLK UCSF GRCh37 5 74892054 74892054 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 49 58 0 ENST00000241436.4:c.1536G>A p.Arg512= p.R512= ENST00000241436 NM_016218.2 512 cgG/cgA 0 +POLQ UCSF GRCh37 3 121208155 121208155 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 170 54 173 0 ENST00000264233.5:c.3623C>T p.Thr1208Ile p.T1208I ENST00000264233 NM_199420.3 1208 aCc/aTc 0 +POLR1B UCSF GRCh37 2 113308465 113308465 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 68 91 0 ENST00000263331.5:c.648G>A p.Arg216= p.R216= ENST00000263331 NM_019014.4 216 agG/agA 0 +POLR3G UCSF GRCh37 5 89781475 89781475 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 56 101 0 ENST00000399107.1:c.91G>A p.Val31Met p.V31M ENST00000399107 NM_006467.2 31 Gtg/Atg 0 +POM121 UCSF GRCh37 7 72413497 72413497 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 378 72 89 0 ENST00000434423.2:c.2965C>T p.Pro989Ser p.P989S ENST00000434423 989 Ccc/Tcc 0 +POM121 UCSF GRCh37 7 72413724 72413725 + inframe_insertion In_Frame_Ins INS - - CTC NOVEL P05_Rec Untested WXS Illumina HiSeq 6 0 ENST00000434423.2:c.3192_3193insCTC p.Phe1064_Phe1065insLeu p.F1064_F1065insL ENST00000434423 1064 -/CTC 0 +POMT1 UCSF GRCh37 9 134395559 134395559 + stop_gained Nonsense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 81 30 37 0 ENST00000372228.3:c.1743C>G p.Tyr581Ter p.Y581* ENST00000372228 NM_007171.3 581 taC/taG 0 +POTED UCSF GRCh37 21 14982904 14982904 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.1135 P05_Rec Untested WXS Illumina HiSeq 261 34 178 1 ENST00000299443.5:c.355G>A p.Ala119Thr p.A119T ENST00000299443 NM_174981.3 119 Gct/Act 0 +POTEF UCSF GRCh37 2 130877870 130877870 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 270 161 206 0 ENST00000357462.5:c.219G>A p.Arg73= p.R73= ENST00000357462 73 agG/agA 0 +POU4F1 UCSF GRCh37 13 79175722 79175722 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 66 40 0 ENST00000377208.5:c.1088C>T p.Ala363Val p.A363V ENST00000377208 NM_006237.3 363 gCc/gTc 0 +PPFIA2 UCSF GRCh37 12 81661691 81661691 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 68 55 0 ENST00000549396.1:c.3486G>A p.Gln1162= p.Q1162= ENST00000549396 NM_003625.3 1162 caG/caA 0 +PPFIBP1 UCSF GRCh37 12 27844847 27844847 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 40 97 0 ENST00000318304.8:c.2869G>A p.Asp957Asn p.D957N ENST00000318304 NM_177444.2 957 Gac/Aac 0 +PPIB UCSF GRCh37 15 64448978 64448978 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 112 82 89 0 ENST00000300026.3:c.474G>A p.Lys158= p.K158= ENST00000300026 NM_000942.4 158 aaG/aaA 0 +PPME1 UCSF GRCh37 11 73962009 73962009 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 36 88 0 ENST00000328257.8:c.1020G>A p.Gln340= p.Q340= ENST00000328257 NM_016147.2 340 caG/caA 0 +PPP1R12A UCSF GRCh37 12 80202309 80202309 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 61 91 0 ENST00000261207.5:c.1504C>T p.Pro502Ser p.P502S ENST00000261207 NM_001143885.1 502 Cca/Tca 0 +PPP1R15B UCSF GRCh37 1 204378931 204378931 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 52 44 63 0 ENST00000367188.4:c.1609T>C p.Ser537Pro p.S537P ENST00000367188 NM_032833.3 537 Tct/Cct 0 +PPP1R9A UCSF GRCh37 7 94539568 94539568 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 34 48 0 ENST00000340694.4:c.143G>A p.Gly48Asp p.G48D ENST00000340694 NM_001166163.1 48 gGt/gAt 0 +PPP1R9B UCSF GRCh37 17 48212917 48212917 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 46 56 0 ENST00000316878.6:c.2394+1G>A p.X798_splice ENST00000316878 NM_032595.3 0 +PPP6R1 UCSF GRCh37 19 55743017 55743017 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 16 10 0 ENST00000412770.2:c.2326C>T p.Pro776Ser p.P776S ENST00000412770 NM_014931.3 776 Ccc/Tcc 0 +PPP6R1 UCSF GRCh37 19 55743302 55743302 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 20 12 0 ENST00000412770.2:c.2174C>T p.Thr725Ile p.T725I ENST00000412770 NM_014931.3 725 aCc/aTc 0 +PPP6R2 UCSF GRCh37 22 50877097 50877097 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 38 33 0 ENST00000216061.5:c.2034G>A p.Lys678= p.K678= ENST00000216061 678 aaG/aaA 0 +PRAMEF1 UCSF GRCh37 1 12854622 12854622 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 153 66 149 0 ENST00000332296.7:c.846G>A p.Gly282= p.G282= ENST00000332296 NM_023013.2 282 ggG/ggA 0 +PRAMEF12 UCSF GRCh37 1 12837214 12837214 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 152 77 135 0 ENST00000357726.4:c.924C>T p.Asp308= p.D308= ENST00000357726 NM_001080830.1 308 gaC/gaT 0 +PRDM10 UCSF GRCh37 11 129800986 129800986 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 56 43 0 ENST00000358825.5:c.1455G>A p.Pro485= p.P485= ENST00000358825 NM_020228.2 485 ccG/ccA 0 +PRDM15 UCSF GRCh37 21 43274688 43274688 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 30 20 0 ENST00000269844.3:c.1623C>T p.Gly541= p.G541= ENST00000269844 NM_022115.3 541 ggC/ggT 0 +PRDM4 UCSF GRCh37 12 108128109 108128109 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 181 83 142 0 ENST00000228437.5:c.2284C>T p.Pro762Ser p.P762S ENST00000228437 NM_012406.3 762 Cca/Tca 0 +PRDM4 UCSF GRCh37 12 108134731 108134731 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 107 47 76 0 ENST00000228437.5:c.1916T>C p.Ile639Thr p.I639T ENST00000228437 NM_012406.3 639 aTa/aCa 0 +PRDM8 UCSF GRCh37 4 81123189 81123189 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 57 48 0 ENST00000339711.4:c.573C>T p.Asp191= p.D191= ENST00000339711 NM_020226.3 191 gaC/gaT 0 +PREP UCSF GRCh37 6 105825268 105825268 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 64 103 0 ENST00000369110.3:c.247G>A p.Gly83Arg p.G83R ENST00000369110 NM_002726.4 83 Gga/Aga 0 +PREX1 UCSF GRCh37 20 47270005 47270005 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 110 55 93 0 ENST00000371941.3:c.2240C>T p.Ala747Val p.A747V ENST00000371941 NM_020820.3 747 gCt/gTt 0 +PREX1 UCSF GRCh37 20 47309310 47309310 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 41 65 0 ENST00000371941.3:c.936G>A p.Lys312= p.K312= ENST00000371941 NM_020820.3 312 aaG/aaA 0 +PREX1 UCSF GRCh37 20 47269244 47269244 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 32 38 0 ENST00000371941.3:c.2347G>A p.Gly783Ser p.G783S ENST00000371941 NM_020820.3 783 Ggc/Agc 0 +PRG4 UCSF GRCh37 1 186276268 186276291 + inframe_deletion In_Frame_Del DEL GAGCCTGCACCCACCACTCCCAAA GAGCCTGCACCCACCACTCCCAAA - NOVEL P05_Rec Untested WXS Illumina HiSeq 33 0 ENST00000445192.2:c.1431_1454del p.Thr478_Thr485del p.T478_T485del ENST00000445192 NM_005807.3 473 GAGCCTGCACCCACCACTCCCAAA/- 0 +PRIMA1 UCSF GRCh37 14 94203672 94203672 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 13 47 0 ENST00000393140.1:c.274G>A p.Gly92Arg p.G92R ENST00000393140 NM_178013.3 92 Ggg/Agg 0 +PRKAB2 UCSF GRCh37 1 146639345 146639345 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 134 85 132 0 ENST00000254101.3:c.323+1G>A p.X108_splice ENST00000254101 NM_005399.4 0 +PRKAG2 UCSF GRCh37 7 151273519 151273519 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 10 16 0 ENST00000287878.4:c.884C>T p.Ala295Val p.A295V ENST00000287878 NM_016203.3 295 gCt/gTt 0 +PRKAR1B UCSF GRCh37 7 720262 720262 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 29 29 0 ENST00000360274.4:c.279C>T p.Ala93= p.A93= ENST00000360274 NM_002735.2 93 gcC/gcT 0 +PRKAR2B UCSF GRCh37 7 106799893 106799893 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 19 75 0 ENST00000265717.4:c.1124-1G>A p.X375_splice ENST00000265717 NM_002736.2 0 +PRKCE UCSF GRCh37 2 46378252 46378252 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 5 19 15 0 ENST00000306156.3:c.1804G>A p.Ala602Thr p.A602T ENST00000306156 NM_005400.2 602 Gct/Act 0 +PRKCH UCSF GRCh37 14 61915909 61915909 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 31 43 0 ENST00000332981.5:c.641G>A p.Cys214Tyr p.C214Y ENST00000332981 NM_006255.3 214 tGc/tAc 0 +PRKCZ UCSF GRCh37 1 2087490 2087490 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 64 120 0 ENST00000378567.3:c.933C>T p.Pro311= p.P311= ENST00000378567 NM_002744.4 311 ccC/ccT 0 +PRKDC UCSF GRCh37 8 48715922 48715922 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 107 60 80 0 ENST00000314191.2:c.9864G>A p.Arg3288= p.R3288= ENST00000314191 NM_006904.6 3288 cgG/cgA 0 +PRKG2 UCSF GRCh37 4 82031649 82031649 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 29 66 0 ENST00000264399.1:c.1893G>A p.Val631= p.V631= ENST00000264399 NM_006259.1 631 gtG/gtA 0 +PRLHR UCSF GRCh37 10 120354123 120354123 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 9 23 10 0 ENST00000239032.2:c.634G>A p.Glu212Lys p.E212K ENST00000239032 NM_004248.2 212 Gag/Aag 0 +PRM3 UCSF GRCh37 16 11367397 11367397 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 6 8 0 ENST00000327157.2:c.56G>A p.Gly19Asp p.G19D ENST00000327157 NM_021247.1 19 gGc/gAc 0 +PROK1 UCSF GRCh37 1 110996646 110996646 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 23 11 0 ENST00000271331.3:c.136G>A p.Gly46Arg p.G46R ENST00000271331 NM_032414.2 46 Ggg/Agg 0 +PROX2 UCSF GRCh37 14 75330486 75330486 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 25 51 0 ENST00000556489.2:c.52C>T p.Leu18= p.L18= ENST00000556489 NM_001243007.1 18 Cta/Tta 0 +PRR14 UCSF GRCh37 16 30664057 30664057 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 42 44 0 ENST00000300835.4:c.208T>A p.Ser70Thr p.S70T ENST00000300835 NM_024031.2 70 Tca/Aca 0 +PRRC2A UCSF GRCh37 6 31592294 31592294 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 22 15 0 ENST00000376007.4:c.458G>A p.Gly153Glu p.G153E ENST00000376007 NM_080686.2 153 gGa/gAa 0 +PRRC2B UCSF GRCh37 9 134350643 134350643 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 41 33 0 ENST00000357304.4:c.3127C>T p.Pro1043Ser p.P1043S ENST00000357304 NM_013318.3 1043 Ccc/Tcc 0 +PRRC2C UCSF GRCh37 1 171509690 171509690 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 62 61 0 ENST00000338920.4:c.3079G>A p.Glu1027Lys p.E1027K ENST00000338920 NM_015172.3 1027 Gaa/Aaa 0 +PRRC2C UCSF GRCh37 1 171514630 171514630 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 42 52 0 ENST00000338920.4:c.4770C>T p.Asp1590= p.D1590= ENST00000338920 NM_015172.3 1590 gaC/gaT 0 +PRSS48 UCSF GRCh37 4 152212490 152212490 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 80 90 0 ENST00000455694.2:c.872C>T p.Pro291Leu p.P291L ENST00000455694 NM_183375.2 291 cCc/cTc 0 +PRSS57 UCSF GRCh37 19 686978 686978 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 19 17 0 ENST00000329267.7:c.592C>T p.Leu198Phe p.L198F ENST00000329267 NM_214710.3 198 Ctt/Ttt 0 +PRUNE UCSF GRCh37 1 150999738 150999738 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 11 32 0 ENST00000271620.3:c.709G>T p.Asp237Tyr p.D237Y ENST00000271620 NM_021222.1 237 Gac/Tac 0 +PSG4 UCSF GRCh37 19 43699353 43699353 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 173 106 226 0 ENST00000405312.3:c.782C>T p.Thr261Ile p.T261I ENST00000405312 NM_002780.4 261 aCc/aTc 0 +PSG8 UCSF GRCh37 19 43259405 43259405 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 86 237 0 ENST00000306511.4:c.723G>A p.Lys241= p.K241= ENST00000306511 NM_182707.2 241 aaG/aaA 0 +PSMD1 UCSF GRCh37 2 232028412 232028412 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 17 35 66 0 ENST00000308696.6:c.2452G>A p.Glu818Lys p.E818K ENST00000308696 NM_002807.3 818 Gaa/Aaa 0 +PSMD2 UCSF GRCh37 3 184017640 184017640 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 114 28 67 0 ENST00000310118.4:c.137C>T p.Ser46Phe p.S46F ENST00000310118 NM_002808.4 46 tCt/tTt 0 +PSME4 UCSF GRCh37 2 54117319 54117319 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 54 102 0 ENST00000404125.1:c.4218C>T p.Cys1406= p.C1406= ENST00000404125 NM_014614.2 1406 tgC/tgT 0 +PSTPIP2 UCSF GRCh37 18 43578776 43578776 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 51 61 0 ENST00000409746.5:c.546C>T p.Thr182= p.T182= ENST00000409746 NM_024430.3 182 acC/acT 0 +PTCH1 UCSF GRCh37 9 98231306 98231306 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 107 48 66 0 ENST00000331920.6:c.1977G>A p.Gln659= p.Q659= ENST00000331920 NM_000264.3 659 caG/caA 0 +PTCHD2 UCSF GRCh37 1 11580875 11580875 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 20 11 0 ENST00000294484.6:c.2332G>A p.Ala778Thr p.A778T ENST00000294484 NM_020780.1 778 Gcc/Acc 0 +PTH1R UCSF GRCh37 3 46939927 46939927 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 17 20 30 0 ENST00000313049.5:c.603C>T p.Ser201= p.S201= ENST00000313049 201 tcC/tcT 0 +PTH2R UCSF GRCh37 2 209358284 209358284 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 106 69 67 0 ENST00000272847.2:c.1553G>A p.Gly518Glu p.G518E ENST00000272847 NM_005048.3 518 gGg/gAg 0 +PTPN13 UCSF GRCh37 4 87691066 87691066 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 147 75 139 0 ENST00000411767.2:c.4634G>A p.Ser1545Asn p.S1545N ENST00000411767 1545 aGt/aAt 0 +PTPN13 UCSF GRCh37 4 87556525 87556525 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 34 62 0 ENST00000411767.2:c.115+1G>A p.X39_splice ENST00000411767 0 +PTPN9 UCSF GRCh37 15 75819501 75819501 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 24 34 0 ENST00000306726.2:c.165G>A p.Lys55= p.K55= ENST00000306726 NM_002833.2 55 aaG/aaA 0 +PTPRB UCSF GRCh37 12 70928355 70928355 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 13 11 0 ENST00000261266.5:c.5627C>T p.Thr1876Ile p.T1876I ENST00000261266 NM_002837.4 1876 aCc/aTc 0 +PTPRD UCSF GRCh37 9 8331732 8331732 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 31 61 0 ENST00000356435.5:c.5384G>A p.Gly1795Asp p.G1795D ENST00000356435 1795 gGc/gAc 0 +PTPRD UCSF GRCh37 9 8518062 8518062 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 140 63 154 0 ENST00000356435.5:c.1329G>A p.Glu443= p.E443= ENST00000356435 443 gaG/gaA 0 +PTPRS UCSF GRCh37 19 5244361 5244361 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 49 50 0 ENST00000357368.4:c.1121G>A p.Gly374Glu p.G374E ENST00000357368 NM_002850.3 374 gGg/gAg 0 +PTPRS UCSF GRCh37 19 5231583 5231583 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 12 11 0 ENST00000357368.4:c.1893C>T p.Arg631= p.R631= ENST00000357368 NM_002850.3 631 cgC/cgT 0 +PTPRZ1 UCSF GRCh37 7 121653840 121653840 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 192 50 146 0 ENST00000393386.2:c.4740G>A p.Gly1580= p.G1580= ENST00000393386 NM_001206838.1 1580 ggG/ggA 0 +PWP2 UCSF GRCh37 21 45545915 45545915 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 30 55 0 ENST00000291576.7:c.1989G>A p.Met663Ile p.M663I ENST00000291576 NM_005049.2 663 atG/atA 0 +PWWP2A UCSF GRCh37 5 159545853 159545853 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 11 18 12 0 ENST00000307063.7:c.543G>A p.Gly181= p.G181= ENST00000307063 NM_001130864.1 181 ggG/ggA 0 +PWWP2B UCSF GRCh37 10 134218986 134218986 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 20 13 0 ENST00000305233.5:c.982C>T p.Leu328= p.L328= ENST00000305233 NM_138499.3 328 Ctg/Ttg 0 +PXK UCSF GRCh37 3 58398660 58398660 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 30 87 0 ENST00000356151.2:c.1498C>T p.Pro500Ser p.P500S ENST00000356151 NM_017771.3 500 Ccg/Tcg 0 +QRICH2 UCSF GRCh37 17 74288835 74288835 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 31 54 0 ENST00000262765.5:c.1475G>A p.Gly492Asp p.G492D ENST00000262765 NM_032134.1 492 gGt/gAt 0 +R3HDM1 UCSF GRCh37 2 136403047 136403047 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 37 53 0 ENST00000264160.4:c.1573C>T p.Pro525Ser p.P525S ENST00000264160 NM_015361.2 525 Cct/Tct 0 +R3HDM2 UCSF GRCh37 12 57662174 57662174 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 36 57 0 ENST00000347140.3:c.1900G>A p.Val634Met p.V634M ENST00000347140 634 Gtg/Atg 0 +RAB32 UCSF GRCh37 6 146870851 146870851 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 21 52 0 ENST00000367495.3:c.502G>A p.Ala168Thr p.A168T ENST00000367495 NM_006834.3 168 Gcc/Acc 0 +RAB36 UCSF GRCh37 22 23503121 23503121 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.236,1000g2011may_all_0.3625,snp132_rs5759611 P05_Rec Untested WXS Illumina HiSeq 55 35 46 1 ENST00000263116.2:c.873G>A p.Ser291= p.S291= ENST00000263116 NM_004914.2 291 tcG/tcA 0 +RAB3D UCSF GRCh37 19 11436176 11436176 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 55 42 0 ENST00000222120.3:c.558G>A p.Lys186= p.K186= ENST00000222120 NM_004283.3 186 aaG/aaA 0 +RAB3GAP1 UCSF GRCh37 2 135926128 135926128 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 65 79 0 ENST00000264158.8:c.2723C>T p.Thr908Ile p.T908I ENST00000264158 NM_012233.2 908 aCt/aTt 0 +RAB5C UCSF GRCh37 17 40280691 40280691 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 44 80 0 ENST00000346213.4:c.294C>T p.Ile98= p.I98= ENST00000346213 NM_004583.3 98 atC/atT 0 +RAD18 UCSF GRCh37 3 8940660 8940660 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 18 49 0 ENST00000264926.2:c.1240G>A p.Glu414Lys p.E414K ENST00000264926 NM_020165.3 414 Gaa/Aaa 0 +RAD18 UCSF GRCh37 3 8940694 8940694 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 106 16 54 0 ENST00000264926.2:c.1206T>C p.Phe402= p.F402= ENST00000264926 NM_020165.3 402 ttT/ttC 0 +RANBP10 UCSF GRCh37 16 67763929 67763929 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 28 28 0 ENST00000317506.3:c.910G>A p.Glu304Lys p.E304K ENST00000317506 NM_020850.1 304 Gag/Aag 0 +RANBP17 UCSF GRCh37 5 170380687 170380687 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 6 14 46 0 ENST00000523189.1:c.1555G>A p.Asp519Asn p.D519N ENST00000523189 NM_022897.3 519 Gat/Aat 0 +RANGAP1 UCSF GRCh37 22 41660817 41660817 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 39 58 0 ENST00000356244.3:c.331G>A p.Gly111Arg p.G111R ENST00000356244 NM_002883.3 111 Ggg/Agg 0 +RASSF2 UCSF GRCh37 20 4776541 4776541 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 37 45 0 ENST00000379376.2:c.207G>A p.Gln69= p.Q69= ENST00000379376 NM_170774.1 69 caG/caA 0 +RB1CC1 UCSF GRCh37 8 53573509 53573509 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 22 52 0 ENST00000025008.5:c.1604G>A p.Arg535Lys p.R535K ENST00000025008 NM_014781.4 535 aGg/aAg 0 +RB1CC1 UCSF GRCh37 8 53569395 53569395 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 137 68 129 0 ENST00000025008.5:c.2994G>A p.Arg998= p.R998= ENST00000025008 NM_014781.4 998 agG/agA 0 +RBAK UCSF GRCh37 7 5097359 5097359 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 29 104 0 ENST00000353796.3:c.187G>A p.Gly63Arg p.G63R ENST00000353796 NM_001204456.1 63 Gga/Aga 0 +RBL2 UCSF GRCh37 16 53487653 53487653 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 44 47 0 ENST00000262133.6:c.964C>T p.Leu322= p.L322= ENST00000262133 NM_005611.3 322 Cta/Tta 0 +RBM14 UCSF GRCh37 11 66392419 66392419 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 105 86 0 ENST00000310137.4:c.1072G>A p.Val358Ile p.V358I ENST00000310137 NM_006328.3 358 Gtt/Att 0 +RBP2 UCSF GRCh37 3 139195235 139195235 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 22 34 0 ENST00000232217.2:c.67G>A p.Ala23Thr p.A23T ENST00000232217 NM_004164.2 23 Gcc/Acc 0 +RBP3 UCSF GRCh37 10 48390586 48390586 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 56 40 0 ENST00000224600.4:c.292C>T p.Pro98Ser p.P98S ENST00000224600 NM_002900.2 98 Cct/Tct 0 +RBPJL UCSF GRCh37 20 43936831 43936831 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 44 30 0 ENST00000343694.3:c.71G>A p.Arg24Lys p.R24K ENST00000343694 NM_001281449.1 24 aGa/aAa 0 +RCCD1 UCSF GRCh37 15 91504989 91504989 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 43 65 0 ENST00000394258.2:c.1121G>A p.Gly374Glu p.G374E ENST00000394258 NM_033544.2 374 gGg/gAg 0 +REEP4 UCSF GRCh37 8 21997031 21997031 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 16 22 0 ENST00000306306.3:c.315G>A p.Ala105= p.A105= ENST00000306306 NM_025232.2 105 gcG/gcA 0 +RELN UCSF GRCh37 7 103183256 103183256 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 69 97 0 ENST00000428762.1:c.6593C>T p.Ser2198Phe p.S2198F ENST00000428762 NM_005045.3 2198 tCt/tTt 0 +RELN UCSF GRCh37 7 103163894 103163894 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 145 56 131 0 ENST00000428762.1:c.7434G>A p.Gly2478= p.G2478= ENST00000428762 NM_005045.3 2478 ggG/ggA 0 +REXO1L1 UCSF GRCh37 8 86575271 86575271 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 8 16 14 0 ENST00000379010.2:c.456G>A p.Gln152= p.Q152= ENST00000379010 NM_172239.4 152 caG/caA 0 +RFWD3 UCSF GRCh37 16 74685996 74685996 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 37 79 0 ENST00000361070.4:c.543C>T p.Tyr181= p.Y181= ENST00000361070 NM_018124.3 181 taC/taT 0 +RFX3 UCSF GRCh37 9 3225266 3225266 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 26 43 0 ENST00000382004.3:c.2026G>A p.Val676Ile p.V676I ENST00000382004 NM_134428.1 676 Gta/Ata 0 +RFX8 UCSF GRCh37 2 102019210 102019210 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 25 37 0 ENST00000428343.1:c.933C>T p.Ser311= p.S311= ENST00000428343 NM_001145664.1 311 tcC/tcT 0 +RGNEF UCSF GRCh37 5 73142300 73142300 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 51 85 0 ENST00000426542.2:c.1635G>A p.Lys545= p.K545= ENST00000426542 545 aaG/aaA 0 +RGPD4 UCSF GRCh37 2 108489331 108489331 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 110 63 230 0 ENST00000408999.3:c.4871C>T p.Ser1624Phe p.S1624F ENST00000408999 NM_182588.2 1624 tCc/tTc 0 +RGS12 UCSF GRCh37 4 3432488 3432488 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 14 10 0 ENST00000336727.3:c.3920C>T p.Ser1307Phe p.S1307F ENST00000336727 NM_002926.3 1307 tCc/tTc 0 +RHBDF1 UCSF GRCh37 16 108500 108500 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 123 79 86 0 ENST00000262316.6:c.2407C>T p.Gln803Ter p.Q803* ENST00000262316 NM_022450.3 803 Cag/Tag 0 +RHBDF2 UCSF GRCh37 17 74469754 74469754 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 7 12 0 ENST00000313080.4:c.1796C>T p.Pro599Leu p.P599L ENST00000313080 NM_024599.5 599 cCc/cTc 0 +RHO UCSF GRCh37 3 129252456 129252456 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 133 47 76 0 ENST00000296271.3:c.942G>A p.Arg314= p.R314= ENST00000296271 NM_000539.3 314 cgG/cgA 0 +RHOBTB3 UCSF GRCh37 5 95088031 95088031 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 61 59 0 ENST00000379982.3:c.659G>A p.Arg220Lys p.R220K ENST00000379982 NM_014899.3 220 aGa/aAa 0 +RICTOR UCSF GRCh37 5 39003668 39003668 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 23 46 0 ENST00000357387.3:c.252C>T p.Ile84= p.I84= ENST00000357387 NM_152756.3 84 atC/atT 0 +RIF1 UCSF GRCh37 2 152331414 152331414 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 14 34 0 ENST00000243326.5:c.7248C>T p.Asn2416= p.N2416= ENST00000243326 2416 aaC/aaT 0 +RIMBP2 UCSF GRCh37 12 130929794 130929794 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 20 45 0 ENST00000261655.4:c.551C>T p.Pro184Leu p.P184L ENST00000261655 NM_015347.4 184 cCg/cTg 0 +RIOK2 UCSF GRCh37 5 96503335 96503335 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 112 67 109 0 ENST00000283109.3:c.1233C>T p.Asn411= p.N411= ENST00000283109 NM_018343.2 411 aaC/aaT 0 +RLTPR UCSF GRCh37 16 67679506 67679506 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 47 30 0 ENST00000334583.6:c.104G>A p.Gly35Glu p.G35E ENST00000334583 NM_001013838.1 35 gGg/gAg 0 +RND3 UCSF GRCh37 2 151328193 151328193 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 23 56 0 ENST00000263895.4:c.431G>A p.Ser144Asn p.S144N ENST00000263895 NM_005168.4 144 aGt/aAt 0 +RNF113B UCSF GRCh37 13 98829236 98829236 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 50 14 0 ENST00000267291.6:c.255G>A p.Ala85= p.A85= ENST00000267291 NM_178861.4 85 gcG/gcA 0 +RNF114 UCSF GRCh37 20 48565871 48565871 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 37 46 0 ENST00000244061.2:c.600G>A p.Arg200= p.R200= ENST00000244061 NM_018683.3 200 cgG/cgA 0 +RNF123 UCSF GRCh37 3 49737668 49737668 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 18 21 0 ENST00000327697.6:c.993G>A p.Val331= p.V331= ENST00000327697 NM_022064.3 331 gtG/gtA 0 +RNF123 UCSF GRCh37 3 49743495 49743495 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 13 36 0 ENST00000327697.6:c.2385G>A p.Lys795= p.K795= ENST00000327697 NM_022064.3 795 aaG/aaA 0 +RNF13 UCSF GRCh37 3 149677842 149677842 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 22 67 0 ENST00000344229.3:c.701-1G>A p.X234_splice ENST00000344229 NM_007282.4 0 +RNF139 UCSF GRCh37 8 125498715 125498715 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 54 97 0 ENST00000303545.3:c.825C>T p.Asp275= p.D275= ENST00000303545 NM_007218.3 275 gaC/gaT 0 +RNF150 UCSF GRCh37 4 141870520 141870520 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 37 102 0 ENST00000515673.2:c.742C>T p.Leu248= p.L248= ENST00000515673 248 Ctg/Ttg 0 +RNF150 UCSF GRCh37 4 141888968 141888968 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 70 113 0 ENST00000515673.2:c.544C>T p.Leu182= p.L182= ENST00000515673 182 Ctg/Ttg 0 +RNF157 UCSF GRCh37 17 74158020 74158020 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 47 69 0 ENST00000269391.6:c.856G>A p.Asp286Asn p.D286N ENST00000269391 NM_052916.2 286 Gac/Aac 0 +RNF17 UCSF GRCh37 13 25428150 25428150 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 41 84 0 ENST00000255324.5:c.3478C>T p.Gln1160Ter p.Q1160* ENST00000255324 NM_031277.2 1160 Cag/Tag 0 +RNF180 UCSF GRCh37 5 63626112 63626112 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 29 52 0 ENST00000389100.4:c.1458G>A p.Leu486= p.L486= ENST00000389100 NM_001113561.1 486 ttG/ttA 0 +RNF2 UCSF GRCh37 1 185069003 185069003 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0015 P05_Rec Untested WXS Illumina HiSeq 88 53 57 0 ENST00000367510.3:c.818G>A p.Arg273Gln p.R273Q ENST00000367510 NM_007212.3 273 cGa/cAa 0 +RNF213 UCSF GRCh37 17 78323679 78323679 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 48 54 0 ENST00000582970.1:c.10061C>T p.Thr3354Ile p.T3354I ENST00000582970 NM_001256071.1 3354 aCc/aTc 0 +RNF213 UCSF GRCh37 17 78293052 78293052 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 138 65 86 0 ENST00000582970.1:c.2964G>A p.Glu988= p.E988= ENST00000582970 NM_001256071.1 988 gaG/gaA 0 +RNF214 UCSF GRCh37 11 117153912 117153912 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 48 20 51 0 ENST00000300650.4:c.2032G>A p.Val678Ile p.V678I ENST00000300650 NM_207343.3 678 Gta/Ata 0 +RNF220 UCSF GRCh37 1 44877999 44877999 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 226 123 212 0 ENST00000355387.2:c.230G>A p.Gly77Asp p.G77D ENST00000355387 77 gGt/gAt 0 +RNF24 UCSF GRCh37 20 3928926 3928926 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 31 25 0 ENST00000336095.6:c.144G>A p.Arg48= p.R48= ENST00000336095 NM_007219.3 48 agG/agA 0 +RNF40 UCSF GRCh37 16 30776630 30776630 + synonymous_variant Silent SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 82 50 64 0 ENST00000324685.6:c.900G>C p.Leu300= p.L300= ENST00000324685 NM_014771.3 300 ctG/ctC 0 +RNF5 UCSF GRCh37 6 32148052 32148052 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 161 76 167 0 ENST00000375094.3:c.492C>T p.Ser164= p.S164= ENST00000375094 NM_006913.3 164 tcC/tcT 0 +RNGTT UCSF GRCh37 6 89388107 89388107 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 37 71 0 ENST00000369485.4:c.1471G>A p.Val491Ile p.V491I ENST00000369485 NM_003800.3 491 Gtt/Att 0 +ROS1 UCSF GRCh37 6 117622266 117622266 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 42 82 0 ENST00000368508.3:c.6604C>T p.Pro2202Ser p.P2202S ENST00000368508 NM_002944.2 2202 Ccc/Tcc 0 +RP1 UCSF GRCh37 8 55534714 55534714 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 40 26 44 0 ENST00000220676.1:c.653C>G p.Ala218Gly p.A218G ENST00000220676 NM_006269.1 218 gCt/gGt 0 +RP1L1 UCSF GRCh37 8 10466129 10466129 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 194 108 182 0 ENST00000382483.3:c.5479G>A p.Gly1827Arg p.G1827R ENST00000382483 NM_178857.5 1827 Gga/Aga 0 +RP1L1 UCSF GRCh37 8 10464965 10464965 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 80 109 0 ENST00000382483.3:c.6643C>T p.Pro2215Ser p.P2215S ENST00000382483 NM_178857.5 2215 Ccg/Tcg 0 +RP2 UCSF GRCh37 X 46713289 46713289 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 47 106 0 ENST00000218340.3:c.481G>A p.Asp161Asn p.D161N ENST00000218340 NM_006915.2 161 Gat/Aat 0 +RPIA UCSF GRCh37 2 88991451 88991451 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 9 8 8 0 ENST00000283646.4:c.235G>A p.Glu79Lys p.E79K ENST00000283646 NM_144563.2 79 Gag/Aag 0 +RPL10A UCSF GRCh37 6 35437987 35437987 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 30 92 0 ENST00000322203.6:c.342G>A p.Glu114= p.E114= ENST00000322203 NM_007104.4 114 gaG/gaA 0 +RPL13 UCSF GRCh37 16 89628061 89628061 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 31 34 0 ENST00000311528.5:c.322G>A p.Glu108Lys p.E108K ENST00000311528 NM_001243130.1 108 Gag/Aag 0 +RPP21 UCSF GRCh37 6 30314507 30314507 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 150 84 121 0 ENST00000433076.2:c.409C>T p.Pro137Ser p.P137S ENST00000433076 NM_001199121.1 137 Ccc/Tcc 0 +RPS6KC1 UCSF GRCh37 1 213251046 213251046 + synonymous_variant Silent SNP A A T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 29 43 0 ENST00000366960.3:c.150A>T p.Val50= p.V50= ENST00000366960 NM_012424.3 50 gtA/gtT 0 +RPS8 UCSF GRCh37 1 45243785 45243785 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 12 7 14 0 ENST00000396651.3:c.501G>A p.Gln167= p.Q167= ENST00000396651 167 caG/caA 0 +RPTOR UCSF GRCh37 17 78704465 78704465 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 44 6 54 0 ENST00000306801.3:c.613T>C p.Ser205Pro p.S205P ENST00000306801 NM_020761.2 205 Tcc/Ccc 0 +RRAGB UCSF GRCh37 X 55757830 55757830 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 14 21 0 ENST00000262850.7:c.411C>T p.Ser137= p.S137= ENST00000262850 NM_016656.3 137 agC/agT 0 +RRN3 UCSF GRCh37 16 15180303 15180303 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 53 120 0 ENST00000198767.6:c.261G>A p.Gln87= p.Q87= ENST00000198767 NM_018427.3 87 caG/caA 0 +RSC1A1 UCSF GRCh37 1 15987061 15987061 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 44 61 0 ENST00000345034.1:c.698G>A p.Ser233Asn p.S233N ENST00000345034 NM_006511.1 233 aGt/aAt 0 +RTEL1 UCSF GRCh37 20 62292654 62292654 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 25 21 0 ENST00000370018.3:c.106G>A p.Val36Met p.V36M ENST00000370018 NM_032957.4 36 Gtg/Atg 0 +RTN1 UCSF GRCh37 14 60212941 60212941 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 37 108 0 ENST00000267484.5:c.500G>A p.Gly167Glu p.G167E ENST00000267484 NM_021136.2 167 gGa/gAa 0 +RTTN UCSF GRCh37 18 67781767 67781767 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 41 78 0 ENST00000255674.6:c.3597C>T p.Ile1199= p.I1199= ENST00000255674 NM_173630.3 1199 atC/atT 0 +RUNDC3A UCSF GRCh37 17 42390577 42390577 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 41 56 0 ENST00000426726.3:c.329G>A p.Ser110Asn p.S110N ENST00000426726 NM_001144825.1 110 aGc/aAc 0 +RXFP2 UCSF GRCh37 13 32339202 32339202 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 32 41 0 ENST00000298386.2:c.348C>T p.Asp116= p.D116= ENST00000298386 NM_130806.3 116 gaC/gaT 0 +RXRG UCSF GRCh37 1 165398050 165398050 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 17 27 0 ENST00000359842.5:c.203C>T p.Ser68Phe p.S68F ENST00000359842 NM_001256570.1 68 tCt/tTt 0 +RYR1 UCSF GRCh37 19 39013693 39013693 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 33 33 0 ENST00000359596.3:c.10285C>T p.Pro3429Ser p.P3429S ENST00000359596 3429 Ccc/Tcc 0 +RYR1 UCSF GRCh37 19 38956832 38956832 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 14 14 0 ENST00000359596.3:c.2972G>A p.Gly991Glu p.G991E ENST00000359596 991 gGg/gAg 0 +RYR1 UCSF GRCh37 19 38968400 38968400 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 12 20 0 ENST00000359596.3:c.4344G>A p.Trp1448Ter p.W1448* ENST00000359596 1448 tgG/tgA 0 +RYR2 UCSF GRCh37 1 237954787 237954787 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 49 81 0 ENST00000366574.2:c.13535C>T p.Ala4512Val p.A4512V ENST00000366574 NM_001035.2 4512 gCt/gTt 0 +SAC3D1 UCSF GRCh37 11 64812037 64812037 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 102 38 34 0 ENST00000398846.1:c.915G>A p.Glu305= p.E305= ENST00000398846 NM_013299.3 305 gaG/gaA 0 +SAFB2 UCSF GRCh37 19 5587911 5587911 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 8 9 0 ENST00000252542.4:c.2606G>A p.Gly869Asp p.G869D ENST00000252542 NM_014649.2 869 gGc/gAc 0 +SALL1 UCSF GRCh37 16 51174240 51174240 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 149 64 47 0 ENST00000251020.4:c.1893C>T p.Thr631= p.T631= ENST00000251020 NM_002968.2 631 acC/acT 0 +SAMD11 UCSF GRCh37 1 865642 865642 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 12 8 12 0 ENST00000598827.1:c.100C>T p.Pro34Ser p.P34S ENST00000598827 34 Ccc/Tcc 0 +SAMD4A UCSF GRCh37 14 55169174 55169174 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 61 91 0 ENST00000392067.3:c.591G>A p.Gly197= p.G197= ENST00000392067 NM_015589.5 197 ggG/ggA 0 +SAP25 UCSF GRCh37 7 100170545 100170545 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 8 9 0 ENST00000538735.1:c.155G>A p.Gly52Asp p.G52D ENST00000538735 NM_001168682.1 52 gGt/gAt 0 +SART1 UCSF GRCh37 11 65743872 65743872 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 25 11 0 ENST00000312397.5:c.1579G>A p.Glu527Lys p.E527K ENST00000312397 NM_005146.4 527 Gag/Aag 0 +SART1 UCSF GRCh37 11 65744536 65744536 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 37 18 0 ENST00000312397.5:c.1909G>A p.Gly637Arg p.G637R ENST00000312397 NM_005146.4 637 Ggg/Agg 0 +SATB2 UCSF GRCh37 2 200188589 200188589 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 24 58 0 ENST00000260926.5:c.1479G>A p.Gln493= p.Q493= ENST00000260926 NM_001172517.1 493 caG/caA 0 +SBDS UCSF GRCh37 7 66459269 66459269 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 189 57 109 0 ENST00000246868.2:c.188G>A p.Gly63Asp p.G63D ENST00000246868 NM_016038.2 63 gGt/gAt 0 +SBNO1 UCSF GRCh37 12 123794257 123794257 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 138 45 90 0 ENST00000420886.2:c.3442G>A p.Asp1148Asn p.D1148N ENST00000420886 NM_001167856.1 1148 Gat/Aat 0 +SCAPER UCSF GRCh37 15 76914126 76914126 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 31 45 0 ENST00000324767.7:c.2690C>T p.Ser897Phe p.S897F ENST00000324767 NM_020843.2 897 tCt/tTt 0 +SCARB1 UCSF GRCh37 12 125267329 125267329 + intron_variant Intron SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 25 59 0 ENST00000415380.2:c.1651+3324G>A *551* ENST00000415380 0 +SCML2 UCSF GRCh37 X 18264916 18264916 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 88 129 0 ENST00000251900.4:c.1603C>T p.Pro535Ser p.P535S ENST00000251900 NM_006089.2 535 Ccc/Tcc 0 +SCML4 UCSF GRCh37 6 108068037 108068037 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 60 40 0 ENST00000369020.3:c.343G>A p.Val115Met p.V115M ENST00000369020 NM_198081.3 115 Gtg/Atg 0 +SCN11A UCSF GRCh37 3 38936098 38936098 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 157 71 116 0 ENST00000302328.3:c.2761G>A p.Glu921Lys p.E921K ENST00000302328 NM_014139.2 921 Gag/Aag 0 +SCN4A UCSF GRCh37 17 62036654 62036654 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 15 32 0 ENST00000435607.1:c.1990G>A p.Gly664Arg p.G664R ENST00000435607 NM_000334.4 664 Gga/Aga 0 +SCN4A UCSF GRCh37 17 62038634 62038634 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 192 96 110 0 ENST00000435607.1:c.1764C>T p.Ile588= p.I588= ENST00000435607 NM_000334.4 588 atC/atT 0 +SCN7A UCSF GRCh37 2 167289148 167289148 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 63 65 0 ENST00000409855.1:c.2272G>A p.Gly758Arg p.G758R ENST00000409855 NM_002976.3 758 Gga/Aga 0 +SCN7A UCSF GRCh37 2 167301309 167301309 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 108 68 121 0 ENST00000409855.1:c.1589G>A p.Ser530Asn p.S530N ENST00000409855 NM_002976.3 530 aGt/aAt 0 +SCN7A UCSF GRCh37 2 167284406 167284406 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 52 67 0 ENST00000409855.1:c.2745G>A p.Lys915= p.K915= ENST00000409855 NM_002976.3 915 aaG/aaA 0 +SCUBE1 UCSF GRCh37 22 43614335 43614335 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 67 60 0 ENST00000360835.4:c.1817C>T p.Ala606Val p.A606V ENST00000360835 NM_173050.3 606 gCc/gTc 0 +SCYL1 UCSF GRCh37 11 65304221 65304221 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 110 47 77 0 ENST00000270176.5:c.1816G>A p.Gly606Arg p.G606R ENST00000270176 NM_020680.3 606 Gga/Aga 0 +SDHA UCSF GRCh37 5 224511 224511 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 204 102 187 0 ENST00000264932.6:c.187G>A p.Asp63Asn p.D63N ENST00000264932 NM_004168.2 63 Gat/Aat 0 +SDK1 UCSF GRCh37 7 4273021 4273021 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 19 31 0 ENST00000404826.2:c.5962G>A p.Glu1988Lys p.E1988K ENST00000404826 NM_152744.3 1988 Gag/Aag 0 +SDK2 UCSF GRCh37 17 71434243 71434243 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0085 P05_Rec Untested WXS Illumina HiSeq 21 9 17 0 ENST00000392650.3:c.776C>T p.Ser259Leu p.S259L ENST00000392650 NM_001144952.1 259 tCg/tTg 0 +SEC16B UCSF GRCh37 1 177913769 177913769 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 153 103 171 0 ENST00000308284.6:c.1808C>T p.Ala603Val p.A603V ENST00000308284 NM_033127.2 603 gCa/gTa 0 +SEC23A UCSF GRCh37 14 39532604 39532604 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 20 35 0 ENST00000307712.6:c.1322G>A p.Gly441Asp p.G441D ENST00000307712 NM_006364.2 441 gGt/gAt 0 +SEC24B UCSF GRCh37 4 110434905 110434905 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 36 74 0 ENST00000265175.5:c.1906C>T p.Pro636Ser p.P636S ENST00000265175 NM_006323.2 636 Cct/Tct 0 +SEC31A UCSF GRCh37 4 83772730 83772730 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 22 60 0 ENST00000355196.2:c.2182C>T p.Arg728Ter p.R728* ENST00000355196 728 Cga/Tga 0 +SEL1L UCSF GRCh37 14 81993276 81993276 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 41 79 0 ENST00000336735.4:c.141C>T p.Asp47= p.D47= ENST00000336735 NM_005065.5 47 gaC/gaT 0 +SEL1L2 UCSF GRCh37 20 13869127 13869127 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 24 34 0 ENST00000284951.5:c.581G>A p.Gly194Glu p.G194E ENST00000284951 194 gGa/gAa 0 +SEL1L3 UCSF GRCh37 4 25759371 25759371 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 17 35 0 ENST00000399878.3:c.3125C>T p.Ser1042Phe p.S1042F ENST00000399878 NM_015187.3 1042 tCc/tTc 0 +SELE UCSF GRCh37 1 169697058 169697058 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 17 103 0 ENST00000333360.7:c.1290C>T p.Cys430= p.C430= ENST00000333360 NM_000450.2 430 tgC/tgT 0 +SEMA3A UCSF GRCh37 7 83590932 83590932 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 151 62 113 0 ENST00000265362.4:c.2071A>C p.Met691Leu p.M691L ENST00000265362 NM_006080.2 691 Atg/Ctg 0 +SEMA3C UCSF GRCh37 7 80418734 80418734 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 50 106 0 ENST00000265361.3:c.1242C>T p.Ile414= p.I414= ENST00000265361 NM_006379.3 414 atC/atT 0 +SEMA3D UCSF GRCh37 7 84751156 84751156 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 27 64 0 ENST00000284136.6:c.52C>T p.Leu18Phe p.L18F ENST00000284136 NM_152754.2 18 Ctt/Ttt 0 +SEMA3F UCSF GRCh37 3 50211247 50211247 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 12 25 0 ENST00000002829.3:c.134C>T p.Ala45Val p.A45V ENST00000002829 NM_004186.3 45 gCc/gTc 0 +SEMA3F UCSF GRCh37 3 50223726 50223726 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 10 13 0 ENST00000002829.3:c.1758G>A p.Arg586= p.R586= ENST00000002829 NM_004186.3 586 cgG/cgA 0 +SEMA3G UCSF GRCh37 3 52474455 52474455 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 15 14 0 ENST00000231721.2:c.1081G>A p.Asp361Asn p.D361N ENST00000231721 NM_020163.1 361 Gat/Aat 0 +SEMA4D UCSF GRCh37 9 91996225 91996225 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 20 9 0 ENST00000356444.2:c.1483G>A p.Val495Met p.V495M ENST00000356444 495 Gtg/Atg 0 +SEMG2 UCSF GRCh37 20 43851472 43851472 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 42 88 0 ENST00000372769.3:c.1199G>A p.Gly400Asp p.G400D ENST00000372769 NM_003008.2 400 gGc/gAc 0 +SERPINA4 UCSF GRCh37 14 95033368 95033368 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 26 54 0 ENST00000298841.5:c.711G>A p.Glu237= p.E237= ENST00000298841 NM_006215.2 237 gaG/gaA 0 +SERPINB11 UCSF GRCh37 18 61377551 61377551 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 48 119 0 ENST00000544088.1:c.124G>A p.Val42Ile p.V42I ENST00000544088 NM_080475.2 42 Gtc/Atc 0 +SERPINB2 UCSF GRCh37 18 61558714 61558714 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 27 48 1 ENST00000299502.4:c.36C>T p.Ala12= p.A12= ENST00000299502 NM_002575.2 12 gcC/gcT 0 +SERPINB6 UCSF GRCh37 6 2948720 2948720 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 50 101 0 ENST00000335686.5:c.943G>A p.Val315Ile p.V315I ENST00000335686 NM_001271824.1 315 Gtc/Atc 0 +SERPINE3 UCSF GRCh37 13 51929249 51929249 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 84 94 0 ENST00000521255.1:c.970C>T p.Pro324Ser p.P324S ENST00000521255 NM_001101320.1 324 Cca/Tca 0 +SETD1A UCSF GRCh37 16 30990750 30990750 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 17 17 0 ENST00000262519.8:c.3643G>A p.Ala1215Thr p.A1215T ENST00000262519 NM_014712.1 1215 Gca/Aca 0 +SETD5 UCSF GRCh37 3 9483315 9483315 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.004,1000g2011may_all_0.01369,snp132_rs17050347 P05_Rec Untested WXS Illumina HiSeq 293 109 148 0 ENST00000402198.1:c.849G>A p.Arg283= p.R283= ENST00000402198 NM_001080517.1 283 cgG/cgA 0 +SETX UCSF GRCh37 9 135221755 135221755 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 24 54 0 ENST00000224140.5:c.281G>A p.Gly94Glu p.G94E ENST00000224140 NM_015046.5 94 gGa/gAa 0 +SEZ6L2 UCSF GRCh37 16 29900010 29900010 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 13 13 0 ENST00000308713.5:c.890C>T p.Ala297Val p.A297V ENST00000308713 NM_001114099.2 297 gCc/gTc 0 +SF3A3 UCSF GRCh37 1 38447484 38447484 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 45 71 0 ENST00000373019.4:c.469-1G>A p.X157_splice ENST00000373019 NM_006802.2 0 +SF3B3 UCSF GRCh37 16 70588362 70588362 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 160 48 108 0 ENST00000302516.5:c.1416C>T p.Ala472= p.A472= ENST00000302516 NM_012426.4 472 gcC/gcT 0 +SFI1 UCSF GRCh37 22 32011115 32011115 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 7 10 0 ENST00000400288.2:c.3150C>T p.Ala1050= p.A1050= ENST00000400288 NM_001007467.2 1050 gcC/gcT 0 +SFMBT1 UCSF GRCh37 3 52941713 52941713 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 31 59 0 ENST00000394752.3:c.1943G>A p.Gly648Glu p.G648E ENST00000394752 NM_016329.3 648 gGg/gAg 0 +SGK2 UCSF GRCh37 20 42203554 42203554 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 12 29 0 ENST00000341458.4:c.783G>A p.Leu261= p.L261= ENST00000341458 NM_016276.3 261 ttG/ttA 0 +SGSH UCSF GRCh37 17 78185869 78185869 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 25 18 0 ENST00000326317.6:c.949+1G>A p.X317_splice ENST00000326317 NM_000199.3 0 +SH3BP2 UCSF GRCh37 4 2831619 2831619 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 58 40 0 ENST00000356331.5:c.986G>A p.Arg329Lys p.R329K ENST00000356331 NM_003023.4 329 aGa/aAa 0 +SH3D21 UCSF GRCh37 1 36785572 36785572 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 39 83 0 ENST00000453908.2:c.1308G>A p.Glu436= p.E436= ENST00000453908 NM_001162530.1 436 gaG/gaA 0 +SHISA6 UCSF GRCh37 17 11145222 11145222 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 102 18 38 0 ENST00000409168.3:c.483G>A p.Pro161= p.P161= ENST00000409168 NM_001173461.1 161 ccG/ccA 0 +SHISA9 UCSF GRCh37 16 13002407 13002407 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 30 79 0 ENST00000558583.1:c.686+5923G>A *229* ENST00000558583 NM_001145204.2 0 +SHROOM3 UCSF GRCh37 4 77357299 77357299 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 56 114 0 ENST00000296043.6:c.94C>T p.Leu32= p.L32= ENST00000296043 NM_020859.3 32 Ctg/Ttg 0 +SHROOM3 UCSF GRCh37 4 77676169 77676169 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 38 61 0 ENST00000296043.6:c.4533G>A p.Arg1511= p.R1511= ENST00000296043 NM_020859.3 1511 agG/agA 0 +SIAH3 UCSF GRCh37 13 46357545 46357545 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 31 35 0 ENST00000400405.2:c.783G>A p.Glu261= p.E261= ENST00000400405 NM_198849.2 261 gaG/gaA 0 +SIDT2 UCSF GRCh37 11 117052778 117052778 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 11 32 0 ENST00000324225.4:c.473C>T p.Thr158Ile p.T158I ENST00000324225 NM_001040455.1 158 aCt/aTt 0 +SIDT2 UCSF GRCh37 11 117063895 117063895 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 233 176 216 0 ENST00000324225.4:c.2132C>T p.Pro711Leu p.P711L ENST00000324225 NM_001040455.1 711 cCc/cTc 0 +SIGLEC1 UCSF GRCh37 20 3673728 3673728 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 18 11 0 ENST00000344754.4:c.3559C>T p.Gln1187Ter p.Q1187* ENST00000344754 NM_023068.3 1187 Cag/Tag 0 +SIGLEC5 UCSF GRCh37 19 52132855 52132855 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 5 12 0 ENST00000534261.2:c.456G>A p.Glu152= p.E152= ENST00000534261 152 gaG/gaA 0 +SIK1 UCSF GRCh37 21 44841865 44841865 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 28 48 0 ENST00000270162.6:c.326G>A p.Gly109Glu p.G109E ENST00000270162 NM_173354.3 109 gGa/gAa 0 +SIK3 UCSF GRCh37 11 116746647 116746647 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 52 76 0 ENST00000292055.4:c.1000C>T p.Leu334= p.L334= ENST00000292055 NM_025164.3 334 Ctg/Ttg 0 +SIPA1L3 UCSF GRCh37 19 38579470 38579470 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 31 52 0 ENST00000222345.6:c.1644G>A p.Arg548= p.R548= ENST00000222345 NM_015073.1 548 agG/agA 0 +SIRT2 UCSF GRCh37 19 39380548 39380548 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 33 60 0 ENST00000249396.7:c.322G>A p.Glu108Lys p.E108K ENST00000249396 NM_012237.3 108 Gag/Aag 0 +SIRT4 UCSF GRCh37 12 120750410 120750410 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 11 56 0 ENST00000202967.4:c.649G>A p.Val217Ile p.V217I ENST00000202967 NM_012240.2 217 Gtc/Atc 0 +SKAP2 UCSF GRCh37 7 26709795 26709795 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 12 35 0 ENST00000345317.2:c.1004G>A p.Gly335Asp p.G335D ENST00000345317 NM_003930.3 335 gGc/gAc 0 +SKIV2L2 UCSF GRCh37 5 54639158 54639158 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 33 76 0 ENST00000230640.5:c.782-1G>A p.X261_splice ENST00000230640 NM_015360.4 0 +SLC12A9 UCSF GRCh37 7 100454542 100454542 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 25 32 0 ENST00000354161.3:c.501C>T p.Asn167= p.N167= ENST00000354161 NM_020246.3 167 aaC/aaT 0 +SLC15A2 UCSF GRCh37 3 121658311 121658311 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 58 75 0 ENST00000489711.1:c.1877C>T p.Ser626Phe p.S626F ENST00000489711 NM_021082.3 626 tCt/tTt 0 +SLC16A14 UCSF GRCh37 2 230910924 230910924 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 31 72 0 ENST00000295190.4:c.918G>A p.Gly306= p.G306= ENST00000295190 NM_152527.4 306 ggG/ggA 0 +SLC18A1 UCSF GRCh37 8 20036854 20036854 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 51 85 0 ENST00000276373.5:c.266C>T p.Thr89Ile p.T89I ENST00000276373 NM_003053.3 89 aCc/aTc 0 +SLC24A6 UCSF GRCh37 12 113756781 113756781 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 19 31 0 ENST00000202831.3:c.790C>T p.Pro264Ser p.P264S ENST00000202831 NM_024959.2 264 Cca/Tca 0 +SLC25A19 UCSF GRCh37 17 73279605 73279605 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 8 28 0 ENST00000320362.3:c.358G>A p.Val120Met p.V120M ENST00000320362 120 Gtg/Atg 0 +SLC26A3 UCSF GRCh37 7 107416971 107416971 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 14 64 0 ENST00000340010.5:c.1603G>A p.Val535Met p.V535M ENST00000340010 NM_000111.2 535 Gtg/Atg 0 +SLC26A6 UCSF GRCh37 3 48666082 48666082 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 41 68 0 ENST00000395550.2:c.1665G>A p.Glu555= p.E555= ENST00000395550 555 gaG/gaA 0 +SLC26A9 UCSF GRCh37 1 205889351 205889351 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 21 47 0 ENST00000367135.3:c.2063C>T p.Ser688Phe p.S688F ENST00000367135 NM_052934.3 688 tCc/tTc 0 +SLC27A4 UCSF GRCh37 9 131107546 131107546 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 128 32 22 0 ENST00000300456.4:c.274G>A p.Ala92Thr p.A92T ENST00000300456 NM_005094.3 92 Gcc/Acc 0 +SLC28A3 UCSF GRCh37 9 86912910 86912910 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 62 123 0 ENST00000376238.4:c.694G>A p.Gly232Arg p.G232R ENST00000376238 NM_001199633.1 232 Gga/Aga 0 +SLC2A2 UCSF GRCh37 3 170716107 170716107 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 22 65 0 ENST00000314251.3:c.1249C>T p.Pro417Ser p.P417S ENST00000314251 NM_001278659.1 417 Ccg/Tcg 0 +SLC2A5 UCSF GRCh37 1 9098964 9098964 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 5 19 0 ENST00000377424.4:c.1021C>T p.Arg341Trp p.R341W ENST00000377424 NM_003039.2 341 Cgg/Tgg 0 +SLC30A8 UCSF GRCh37 8 118165280 118165280 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 28 37 0 ENST00000456015.2:c.369G>A p.Leu123= p.L123= ENST00000456015 NM_173851.2 123 ttG/ttA 0 +SLC33A1 UCSF GRCh37 3 155571041 155571041 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 20 21 0 ENST00000359479.3:c.746C>T p.Pro249Leu p.P249L ENST00000359479 NM_004733.3 249 cCt/cTt 0 +SLC35B2 UCSF GRCh37 6 44222530 44222530 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 37 52 0 ENST00000393812.3:c.1212C>T p.Ala404= p.A404= ENST00000393812 NM_178148.2 404 gcC/gcT 0 +SLC35F5 UCSF GRCh37 2 114493359 114493359 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 17 13 0 ENST00000245680.2:c.827C>T p.Thr276Ile p.T276I ENST00000245680 NM_025181.2 276 aCt/aTt 0 +SLC35G6 UCSF GRCh37 17 7385318 7385318 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 37 24 0 ENST00000412468.2:c.15C>T p.His5= p.H5= ENST00000412468 NM_001102614.1 5 caC/caT 0 +SLC38A3 UCSF GRCh37 3 50255394 50255394 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 57 91 0 ENST00000420502.1:n.1054C>T *352* ENST00000420502 0 +SLC38A8 UCSF GRCh37 16 84050245 84050245 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 44 33 0 ENST00000299709.3:c.1041G>A p.Arg347= p.R347= ENST00000299709 NM_001080442.1 347 cgG/cgA 0 +SLC39A2 UCSF GRCh37 14 21467698 21467698 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 37 118 0 ENST00000298681.4:c.93G>A p.Trp31Ter p.W31* ENST00000298681 NM_014579.3 31 tgG/tgA 0 +SLC41A2 UCSF GRCh37 12 105260296 105260296 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 33 60 0 ENST00000258538.3:c.1089G>A p.Trp363Ter p.W363* ENST00000258538 NM_032148.3 363 tgG/tgA 0 +SLC4A10 UCSF GRCh37 2 162807267 162807267 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 40 40 0 ENST00000446997.1:c.2450C>T p.Ala817Val p.A817V ENST00000446997 NM_001178015.1 817 gCt/gTt 0 +SLC4A2 UCSF GRCh37 7 150762019 150762019 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 33 32 0 ENST00000413384.2:c.544G>A p.Ala182Thr p.A182T ENST00000413384 NM_003040.3 182 Gcg/Acg 0 +SLC4A2 UCSF GRCh37 7 150768682 150768682 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 21 21 0 ENST00000413384.2:c.2181G>A p.Gly727= p.G727= ENST00000413384 NM_003040.3 727 ggG/ggA 0 +SLC4A3 UCSF GRCh37 2 220500543 220500543 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 9 12 9 0 ENST00000317151.3:c.2121G>A p.Gln707= p.Q707= ENST00000317151 707 caG/caA 0 +SLC4A7 UCSF GRCh37 3 27424686 27424686 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 30 53 0 ENST00000295736.5:c.3521G>A p.Gly1174Glu p.G1174E ENST00000295736 NM_003615.4 1174 gGg/gAg 0 +SLC4A7 UCSF GRCh37 3 27453176 27453176 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 19 28 0 ENST00000295736.5:c.1696G>A p.Glu566Lys p.E566K ENST00000295736 NM_003615.4 566 Gag/Aag 0 +SLC5A3 UCSF GRCh37 21 35468772 35468772 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 44 64 0 ENST00000381151.3:c.1275G>A p.Trp425Ter p.W425* ENST00000381151 425 tgG/tgA 0 +SLC5A5 UCSF GRCh37 19 17986865 17986865 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 28 42 0 ENST00000222248.3:c.648C>T p.Pro216= p.P216= ENST00000222248 NM_000453.2 216 ccC/ccT 0 +SLC5A6 UCSF GRCh37 2 27426165 27426165 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 31 62 0 ENST00000310574.3:c.1143C>T p.Asp381= p.D381= ENST00000310574 NM_021095.2 381 gaC/gaT 0 +SLC5A9 UCSF GRCh37 1 48703449 48703449 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 22 45 0 ENST00000438567.2:c.1391C>T p.Thr464Ile p.T464I ENST00000438567 NM_001011547.2 464 aCc/aTc 0 +SLC6A14 UCSF GRCh37 X 115577980 115577980 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 54 39 0 ENST00000371900.4:c.863G>A p.Gly288Asp p.G288D ENST00000371900 NM_007231.3 288 gGt/gAt 0 +SLC6A16 UCSF GRCh37 19 49812602 49812602 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 13 51 0 ENST00000335875.4:c.943C>T p.Leu315= p.L315= ENST00000335875 NM_014037.2 315 Ctg/Ttg 0 +SLC6A18 UCSF GRCh37 5 1225747 1225747 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 33 40 0 ENST00000324642.3:c.155G>A p.Gly52Glu p.G52E ENST00000324642 NM_182632.2 52 gGa/gAa 0 +SLC6A20 UCSF GRCh37 3 45817423 45817423 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 53 62 0 ENST00000358525.4:c.412G>A p.Glu138Lys p.E138K ENST00000358525 NM_020208.3 138 Gag/Aag 0 +SLC7A6 UCSF GRCh37 16 68325475 68325475 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 56 89 0 ENST00000219343.6:c.933G>A p.Gln311= p.Q311= ENST00000219343 NM_003983.5 311 caG/caA 0 +SLC8A2 UCSF GRCh37 19 47935511 47935511 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 49 54 0 ENST00000236877.6:c.2302G>A p.Asp768Asn p.D768N ENST00000236877 NM_015063.2 768 Gac/Aac 0 +SLC9A3 UCSF GRCh37 5 476142 476142 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 11 8 0 ENST00000264938.3:c.2133G>A p.Lys711= p.K711= ENST00000264938 NM_004174.2 711 aaG/aaA 0 +SLC9A5 UCSF GRCh37 16 67289019 67289019 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 46 56 0 ENST00000299798.11:c.586G>A p.Val196Met p.V196M ENST00000299798 NM_004594.2 196 Gtg/Atg 0 +SLC9A8 UCSF GRCh37 20 48503313 48503313 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 51 25 0 ENST00000361573.2:c.1516C>T p.Leu506= p.L506= ENST00000361573 506 Ctg/Ttg 0 +SLFN12L UCSF GRCh37 17 33802212 33802212 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 214 122 259 0 ENST00000260908.7:c.1497G>A p.Lys499= p.K499= ENST00000260908 NM_001195790.1 499 aaG/aaA 0 +SMAD4 UCSF GRCh37 18 48573634 48573634 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 57 88 0 ENST00000342988.3:c.218C>T p.Thr73Ile p.T73I ENST00000342988 NM_005359.5 73 aCc/aTc 0 +SMAD6 UCSF GRCh37 15 67073393 67073393 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 11 10 0 ENST00000288840.5:c.1011G>A p.Trp337Ter p.W337* ENST00000288840 NM_005585.4 337 tgG/tgA 0 +SMAD7 UCSF GRCh37 18 46448254 46448254 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 25 64 0 ENST00000262158.2:c.769G>A p.Asp257Asn p.D257N ENST00000262158 NM_001190821.1 257 Gat/Aat 0 +SMAP2 UCSF GRCh37 1 40872408 40872408 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 47 88 0 ENST00000372718.3:c.104G>A p.Gly35Glu p.G35E ENST00000372718 NM_022733.2 35 gGg/gAg 0 +SMARCA4 UCSF GRCh37 19 11144135 11144135 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 120 85 31 0 ENST00000344626.4:c.3716C>T p.Ser1239Phe p.S1239F ENST00000344626 NM_003072.3 1239 tCc/tTc 0 +SMARCB1 UCSF GRCh37 22 24167504 24167504 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 38 58 0 ENST00000263121.7:c.888G>A p.Lys296= p.K296= ENST00000263121 NM_003073.3 296 aaG/aaA 0 +SMCR8 UCSF GRCh37 17 18220997 18220997 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 56 77 0 ENST00000406438.3:c.1894G>A p.Val632Met p.V632M ENST00000406438 NM_144775.2 632 Gtg/Atg 0 +SMG6 UCSF GRCh37 17 1972222 1972222 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 15 21 0 ENST00000263073.6:c.3685G>A p.Val1229Ile p.V1229I ENST00000263073 NM_017575.4 1229 Gtc/Atc 0 +SNAPC4 UCSF GRCh37 9 139292825 139292825 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 235 73 92 0 ENST00000298532.2:c.56G>A p.Arg19Lys p.R19K ENST00000298532 NM_003086.2 19 aGg/aAg 0 +SNAPC4 UCSF GRCh37 9 139282275 139282275 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 94 34 42 0 ENST00000298532.2:c.1149C>T p.Asp383= p.D383= ENST00000298532 NM_003086.2 383 gaC/gaT 0 +SNRNP200 UCSF GRCh37 2 96953181 96953181 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 53 84 0 ENST00000323853.5:c.3480G>A p.Glu1160= p.E1160= ENST00000323853 NM_014014.4 1160 gaG/gaA 0 +SNX13 UCSF GRCh37 7 17930075 17930075 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 64 72 0 ENST00000428135.3:c.351G>A p.Gln117= p.Q117= ENST00000428135 NM_015132.4 117 caG/caA 0 +SOCS2 UCSF GRCh37 12 93968767 93968767 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 38 93 0 ENST00000340600.2:c.409C>T p.Arg137Trp p.R137W ENST00000340600 NM_003877.4 137 Cgg/Tgg 0 +SORT1 UCSF GRCh37 1 109857328 109857328 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 29 20 0 ENST00000256637.6:c.2323G>A p.Val775Met p.V775M ENST00000256637 NM_002959.5 775 Gtg/Atg 0 +SOX11 UCSF GRCh37 2 5833235 5833235 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 21 8 0 ENST00000322002.3:c.382C>T p.Pro128Ser p.P128S ENST00000322002 NM_003108.3 128 Ccc/Tcc 0 +SP110 UCSF GRCh37 2 231042370 231042370 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 84 191 0 ENST00000358662.4:c.1474G>A p.Glu492Lys p.E492K ENST00000358662 NM_004509.3 492 Gag/Aag 0 +SPAG1 UCSF GRCh37 8 101251583 101251583 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 64 103 0 ENST00000251809.3:c.2231C>T p.Thr744Ile p.T744I ENST00000251809 NM_172218.2 744 aCa/aTa 0 +SPDYE3 UCSF GRCh37 7 99917195 99917195 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 288 130 256 0 ENST00000332397.6:c.1354G>A p.Ala452Thr p.A452T ENST00000332397 NM_001004351.4 452 Gcc/Acc 0 +SPHKAP UCSF GRCh37 2 228883799 228883799 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 34 45 0 ENST00000392056.3:c.1771C>T p.Pro591Ser p.P591S ENST00000392056 NM_001142644.1 591 Cct/Tct 0 +SPIN1 UCSF GRCh37 9 91083400 91083400 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 62 87 0 ENST00000375859.3:c.469G>A p.Ala157Thr p.A157T ENST00000375859 NM_006717.2 157 Gca/Aca 0 +SPINT1 UCSF GRCh37 15 41136919 41136919 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 12 9 0 ENST00000344051.4:c.167C>T p.Ala56Val p.A56V ENST00000344051 56 gCc/gTc 0 +SPOP UCSF GRCh37 17 47700133 47700133 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 71 39 87 0 ENST00000347630.2:c.40T>G p.Ser14Ala p.S14A ENST00000347630 NM_001007230.1 14 Tcg/Gcg 0 +SPR UCSF GRCh37 2 73118536 73118536 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 15 40 0 ENST00000234454.5:c.656G>A p.Arg219Gln p.R219Q ENST00000234454 NM_003124.4 219 cGa/cAa 0 +SPRR2D UCSF GRCh37 1 153012683 153012683 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 61 121 0 ENST00000360379.3:c.140C>T p.Pro47Leu p.P47L ENST00000360379 NM_006945.4 47 cCt/cTt 0 +SPTA1 UCSF GRCh37 1 158644362 158644362 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 158 103 91 0 ENST00000368147.4:c.1216G>A p.Glu406Lys p.E406K ENST00000368147 NM_003126.2 406 Gaa/Aaa 0 +SRCAP UCSF GRCh37 16 30735216 30735216 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 54 84 0 ENST00000262518.4:c.4471C>T p.Pro1491Ser p.P1491S ENST00000262518 NM_006662.2 1491 Ccc/Tcc 0 +SRD5A3 UCSF GRCh37 4 56230317 56230317 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 121 71 113 0 ENST00000264228.4:c.441C>T p.Cys147= p.C147= ENST00000264228 NM_024592.4 147 tgC/tgT 0 +SREBF2 UCSF GRCh37 22 42298982 42298982 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 9 8 0 ENST00000361204.4:c.2916G>A p.Gln972= p.Q972= ENST00000361204 NM_004599.3 972 caG/caA 0 +SRGAP1 UCSF GRCh37 12 64536317 64536317 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 52 124 0 ENST00000355086.3:c.3123G>A p.Met1041Ile p.M1041I ENST00000355086 NM_020762.2 1041 atG/atA 0 +SRGAP3 UCSF GRCh37 3 9057317 9057317 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 21 60 0 ENST00000383836.3:c.1777C>T p.Pro593Ser p.P593S ENST00000383836 NM_014850.3 593 Cct/Tct 0 +SRL UCSF GRCh37 16 4247874 4247874 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 11 43 0 ENST00000399609.3:c.302C>T p.Pro101Leu p.P101L ENST00000399609 NM_001098814.1 101 cCg/cTg 0 +SRM UCSF GRCh37 1 11118930 11118930 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 6 8 0 ENST00000376957.2:c.308G>A p.Gly103Glu p.G103E ENST00000376957 NM_003132.2 103 gGa/gAa 0 +SRRD UCSF GRCh37 22 26882013 26882013 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 40 49 0 ENST00000215917.7:c.234C>T p.Phe78= p.F78= ENST00000215917 NM_001013694.2 78 ttC/ttT 0 +SRRM2 UCSF GRCh37 16 2811898 2811898 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 203 114 126 0 ENST00000301740.8:c.1369C>T p.Pro457Ser p.P457S ENST00000301740 NM_016333.3 457 Ccc/Tcc 0 +SRRM2 UCSF GRCh37 16 2809654 2809654 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 29 72 0 ENST00000301740.8:c.825C>T p.Ser275= p.S275= ENST00000301740 NM_016333.3 275 tcC/tcT 0 +SRSF12 UCSF GRCh37 6 89808575 89808575 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 193 135 247 0 ENST00000452027.2:c.508C>T p.Pro170Ser p.P170S ENST00000452027 NM_080743.4 170 Cca/Tca 0 +SRSF9 UCSF GRCh37 12 120899861 120899861 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 42 34 0 ENST00000229390.3:c.627G>A p.Arg209= p.R209= ENST00000229390 NM_003769.2 209 agG/agA 0 +SS18L1 UCSF GRCh37 20 60737983 60737983 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 15 15 0 ENST00000331758.3:c.552C>T p.Asn184= p.N184= ENST00000331758 NM_198935.1 184 aaC/aaT 0 +SSC5D UCSF GRCh37 19 56029025 56029025 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 74 130 0 ENST00000389623.6:c.3382G>A p.Asp1128Asn p.D1128N ENST00000389623 NM_001144950.1 1128 Gac/Aac 0 +SSPO UCSF GRCh37 7 149528267 149528267 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 7 15 0 ENST00000378016.2:n.15186C>T *5062* ENST00000378016 0 +ST6GAL2 UCSF GRCh37 2 107423348 107423348 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 17 33 0 ENST00000361686.4:c.1376C>T p.Ser459Phe p.S459F ENST00000361686 NM_032528.2 459 tCc/tTc 0 +ST6GALNAC1 UCSF GRCh37 17 74621610 74621610 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 13 31 0 ENST00000156626.7:c.1606-1G>A p.X536_splice ENST00000156626 NM_018414.3 0 +ST6GALNAC5 UCSF GRCh37 1 77510220 77510220 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 242 124 100 0 ENST00000477717.1:c.593G>A p.Arg198Gln p.R198Q ENST00000477717 NM_030965.1 198 cGg/cAg 0 +STAC3 UCSF GRCh37 12 57643386 57643386 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 27 27 0 ENST00000332782.2:c.34C>T p.Pro12Ser p.P12S ENST00000332782 NM_145064.1 12 Ccc/Tcc 0 +STAG3 UCSF GRCh37 7 99798542 99798542 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 27 50 0 ENST00000317296.5:c.2011G>A p.Val671Ile p.V671I ENST00000317296 NM_012447.2 671 Gta/Ata 0 +STEAP3 UCSF GRCh37 2 120003184 120003184 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 27 41 0 ENST00000393106.2:c.112G>A p.Asp38Asn p.D38N ENST00000393106 NM_018234.2 38 Gac/Aac 0 +STK17A UCSF GRCh37 7 43647960 43647960 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 40 76 0 ENST00000319357.5:c.525C>T p.His175= p.H175= ENST00000319357 NM_004760.2 175 caC/caT 0 +STK17B UCSF GRCh37 2 197002250 197002250 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 44 87 0 ENST00000263955.4:c.1040G>A p.Ser347Asn p.S347N ENST00000263955 NM_004226.3 347 aGc/aAc 0 +STK36 UCSF GRCh37 2 219563972 219563972 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 44 53 0 ENST00000295709.3:c.3705G>A p.Gln1235= p.Q1235= ENST00000295709 NM_015690.4 1235 caG/caA 0 +STON2 UCSF GRCh37 14 81743681 81743681 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 59 61 0 ENST00000267540.2:c.1974C>T p.Asn658= p.N658= ENST00000267540 NM_033104.3 658 aaC/aaT 0 +STRAP UCSF GRCh37 12 16048406 16048406 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 68 26 57 0 ENST00000419869.2:c.614C>G p.Ser205Cys p.S205C ENST00000419869 NM_007178.3 205 tCt/tGt 0 +STXBP3 UCSF GRCh37 1 109319021 109319021 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 19 23 0 ENST00000370008.3:c.660G>A p.Lys220= p.K220= ENST00000370008 NM_007269.2 220 aaG/aaA 0 +SUPT5H UCSF GRCh37 19 39960873 39960873 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 81 91 0 ENST00000432763.2:c.1489G>A p.Glu497Lys p.E497K ENST00000432763 NM_001111020.2 497 Gag/Aag 0 +SVEP1 UCSF GRCh37 9 113244691 113244691 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 49 70 0 ENST00000374469.1:c.2051C>T p.Thr684Ile p.T684I ENST00000374469 684 aCt/aTt 0 +SYMPK UCSF GRCh37 19 46357650 46357650 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 33 33 0 ENST00000245934.7:c.104G>A p.Arg35Lys p.R35K ENST00000245934 NM_004819.2 35 aGg/aAg 0 +SYNE1 UCSF GRCh37 6 152640094 152640094 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 30 49 0 ENST00000367255.5:c.16293C>T p.Ser5431= p.S5431= ENST00000367255 NM_182961.3 5431 agC/agT 0 +SYNE2 UCSF GRCh37 14 64518895 64518895 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 112 41 150 0 ENST00000344113.4:c.8264C>T p.Pro2755Leu p.P2755L ENST00000344113 NM_015180.4 2755 cCc/cTc 0 +SYNE2 UCSF GRCh37 14 64554542 64554542 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 37 72 0 ENST00000344113.4:c.11638G>A p.Glu3880Lys p.E3880K ENST00000344113 NM_015180.4 3880 Gaa/Aaa 0 +SYNE2 UCSF GRCh37 14 64608671 64608671 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 13 44 0 ENST00000344113.4:c.15171G>A p.Glu5057= p.E5057= ENST00000344113 NM_015180.4 5057 gaG/gaA 0 +SYNGR1 UCSF GRCh37 22 39770548 39770548 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 36 40 0 ENST00000328933.5:c.327C>T p.Ile109= p.I109= ENST00000328933 NM_004711.4 109 atC/atT 0 +SYNRG UCSF GRCh37 17 35930949 35930949 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 50 131 0 ENST00000339208.6:c.1134C>T p.Asn378= p.N378= ENST00000339208 NM_001163544.1 378 aaC/aaT 0 +SYTL4 UCSF GRCh37 X 99956471 99956471 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 42 96 0 ENST00000263033.5:c.309G>A p.Lys103= p.K103= ENST00000263033 NM_001129896.2 103 aaG/aaA 0 +TAAR6 UCSF GRCh37 6 132891711 132891711 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 116 65 127 0 ENST00000275198.1:c.251C>T p.Thr84Ile p.T84I ENST00000275198 NM_175067.1 84 aCt/aTt 0 +TAAR9 UCSF GRCh37 6 132860441 132860441 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 17 13 0 ENST00000434551.1:c.1013C>T p.Thr338Ile p.T338I ENST00000434551 NM_175057.3 338 aCt/aTt 0 +TACR3 UCSF GRCh37 4 104510962 104510962 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 104 80 137 0 ENST00000304883.2:c.1275G>A p.Arg425= p.R425= ENST00000304883 NM_001059.2 425 cgG/cgA 0 +TADA1 UCSF GRCh37 1 166831645 166831645 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 32 61 0 ENST00000367874.4:c.335G>A p.Arg112Lys p.R112K ENST00000367874 NM_053053.3 112 aGa/aAa 0 +TAF3 UCSF GRCh37 10 8056708 8056708 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 107 50 65 0 ENST00000344293.5:c.2784C>T p.Ala928= p.A928= ENST00000344293 NM_031923.3 928 gcC/gcT 0 +TAF5L UCSF GRCh37 1 229730455 229730455 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 143 83 66 0 ENST00000258281.2:c.1359G>A p.Trp453Ter p.W453* ENST00000258281 NM_014409.3 453 tgG/tgA 0 +TANC1 UCSF GRCh37 2 160035165 160035165 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 38 62 0 ENST00000263635.6:c.2001G>A p.Arg667= p.R667= ENST00000263635 NM_033394.2 667 agG/agA 0 +TANC2 UCSF GRCh37 17 61489467 61489467 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 46 73 0 ENST00000424789.2:c.3652C>T p.Leu1218Phe p.L1218F ENST00000424789 NM_025185.3 1218 Ctt/Ttt 0 +TAOK3 UCSF GRCh37 12 118619193 118619193 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 45 65 1 ENST00000392533.3:c.1549G>A p.Ala517Thr p.A517T ENST00000392533 NM_016281.3 517 Gct/Act 0 +TAPT1 UCSF GRCh37 4 16177816 16177816 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 56 69 0 ENST00000405303.2:c.1033G>A p.Val345Ile p.V345I ENST00000405303 NM_153365.2 345 Gta/Ata 0 +TARBP1 UCSF GRCh37 1 234556505 234556505 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 35 62 0 ENST00000040877.1:c.3498C>T p.His1166= p.H1166= ENST00000040877 NM_005646.3 1166 caC/caT 0 +TAS2R5 UCSF GRCh37 7 141490830 141490830 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 60 92 0 ENST00000247883.4:c.669C>T p.Ser223= p.S223= ENST00000247883 NM_018980.2 223 tcC/tcT 0 +TBC1D13 UCSF GRCh37 9 131568554 131568554 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 30 34 0 ENST00000372648.5:c.1101G>A p.Leu367= p.L367= ENST00000372648 NM_018201.3 367 ctG/ctA 0 +TBC1D14 UCSF GRCh37 4 6925123 6925123 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 126 75 91 0 ENST00000409757.4:c.7G>A p.Asp3Asn p.D3N ENST00000409757 NM_020773.2 3 Gat/Aat 0 +TBC1D15 UCSF GRCh37 12 72291654 72291654 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 43 76 0 ENST00000550746.1:c.1167G>A p.Gln389= p.Q389= ENST00000550746 NM_022771.4 389 caG/caA 0 +TBC1D17 UCSF GRCh37 19 50385388 50385388 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 188 96 101 0 ENST00000221543.5:c.618G>A p.Gln206= p.Q206= ENST00000221543 NM_024682.2 206 caG/caA 0 +TBC1D22B UCSF GRCh37 6 37250008 37250008 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 33 60 0 ENST00000373491.3:c.469C>T p.Leu157Phe p.L157F ENST00000373491 NM_017772.2 157 Ctc/Ttc 0 +TBC1D24 UCSF GRCh37 16 2546449 2546449 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 37 20 0 ENST00000293970.5:c.300G>A p.Gln100= p.Q100= ENST00000293970 NM_001199107.1 100 caG/caA 0 +TBK1 UCSF GRCh37 12 64879234 64879234 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 12 12 21 0 ENST00000331710.5:c.1190-1G>A p.X397_splice ENST00000331710 NM_013254.3 0 +TBL1X UCSF GRCh37 X 9652205 9652205 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 26 59 0 ENST00000217964.7:c.334G>A p.Glu112Lys p.E112K ENST00000217964 NM_005647.3 112 Gag/Aag 0 +TBL1XR1 UCSF GRCh37 3 176752054 176752054 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 50 45 59 0 ENST00000430069.1:c.1182T>G p.Ile394Met p.I394M ENST00000430069 394 atT/atG 0 +TBX6 UCSF GRCh37 16 30097950 30097950 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 10 16 0 ENST00000279386.2:c.980C>T p.Ala327Val p.A327V ENST00000279386 327 gCc/gTc 0 +TCF4 UCSF GRCh37 18 52924585 52924585 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 44 77 0 ENST00000356073.4:c.1107C>T p.Ala369= p.A369= ENST00000356073 NM_003199.2 369 gcC/gcT 0 +TCHH UCSF GRCh37 1 152080381 152080381 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 118 60 87 0 ENST00000368804.1:c.5312G>A p.Arg1771Lys p.R1771K ENST00000368804 NM_007113.3 1771 aGa/aAa 0 +TCHH UCSF GRCh37 1 152083503 152083503 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 195 128 83 0 ENST00000368804.1:c.2190G>A p.Arg730= p.R730= ENST00000368804 NM_007113.3 730 agG/agA 0 +TCP1 UCSF GRCh37 6 160200142 160200142 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 46 88 0 ENST00000321394.7:c.1606G>A p.Glu536Lys p.E536K ENST00000321394 NM_030752.2 536 Gaa/Aaa 0 +TCP11 UCSF GRCh37 6 35090045 35090045 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 40 91 0 ENST00000512012.1:c.427G>A p.Asp143Asn p.D143N ENST00000512012 143 Gac/Aac 0 +TCP11L2 UCSF GRCh37 12 106715328 106715328 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 63 25 58 0 ENST00000299045.3:c.479A>C p.Asp160Ala p.D160A ENST00000299045 NM_152772.1 160 gAc/gCc 0 +TDRD10 UCSF GRCh37 1 154515281 154515281 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 19 26 0 ENST00000368480.3:c.487G>A p.Val163Ile p.V163I ENST00000368480 163 Gtc/Atc 0 +TDRD9 UCSF GRCh37 14 104441851 104441851 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 62 120 0 ENST00000409874.4:c.972G>A p.Glu324= p.E324= ENST00000409874 NM_153046.2 324 gaG/gaA 0 +TEAD4 UCSF GRCh37 12 3129818 3129818 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 20 19 0 ENST00000359864.2:c.602G>A p.Gly201Glu p.G201E ENST00000359864 NM_003213.3 201 gGg/gAg 0 +TECPR1 UCSF GRCh37 7 97867907 97867907 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 39 79 0 ENST00000447648.2:c.949G>A p.Gly317Ser p.G317S ENST00000447648 NM_015395.2 317 Ggc/Agc 0 +TENC1 UCSF GRCh37 12 53453496 53453496 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 34 16 0 ENST00000314250.6:c.2071C>T p.Pro691Ser p.P691S ENST00000314250 NM_170754.2 691 Cca/Tca 0 +TEP1 UCSF GRCh37 14 20852280 20852280 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 23 35 0 ENST00000262715.5:c.3451G>A p.Asp1151Asn p.D1151N ENST00000262715 NM_007110.4 1151 Gac/Aac 0 +TERF2 UCSF GRCh37 16 69419376 69419376 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 141 57 56 0 ENST00000254942.3:c.393G>A p.Arg131= p.R131= ENST00000254942 NM_005652.4 131 agG/agA 0 +TET2 UCSF GRCh37 4 106158049 106158049 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 43 94 0 ENST00000380013.4:c.2950G>A p.Glu984Lys p.E984K ENST00000380013 NM_001127208.2 984 Gaa/Aaa 0 +TEX11 UCSF GRCh37 X 69830352 69830352 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 62 99 0 ENST00000344304.3:c.1837+1G>A p.X613_splice ENST00000344304 0 +TEX15 UCSF GRCh37 8 30706062 30706062 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 24 96 0 ENST00000256246.2:c.472C>T p.Pro158Ser p.P158S ENST00000256246 NM_031271.3 158 Cca/Tca 0 +TFAP2E UCSF GRCh37 1 36056336 36056336 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 8 13 0 ENST00000373235.3:c.1006G>A p.Gly336Arg p.G336R ENST00000373235 NM_178548.3 336 Ggg/Agg 0 +TFB2M UCSF GRCh37 1 246711846 246711846 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 24 44 0 ENST00000366514.4:c.858+1G>A p.X286_splice ENST00000366514 NM_022366.2 0 +TGM2 UCSF GRCh37 20 36770591 36770591 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 26 52 0 ENST00000361475.2:c.870C>T p.Cys290= p.C290= ENST00000361475 NM_004613.2 290 tgC/tgT 0 +TGM7 UCSF GRCh37 15 43571977 43571977 + synonymous_variant Silent SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 169 24 57 1 ENST00000452443.2:c.1524G>T p.Leu508= p.L508= ENST00000452443 NM_052955.2 508 ctG/ctT 0 +TH1L UCSF GRCh37 20 57568578 57568578 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 27 60 0 ENST00000602795.1:c.1473C>T p.Ser491= p.S491= ENST00000602795 NM_198976.2 491 tcC/tcT 0 +THBS1 UCSF GRCh37 15 39880853 39880853 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 22 29 0 ENST00000260356.5:c.1598G>A p.Gly533Asp p.G533D ENST00000260356 NM_003246.2 533 gGt/gAt 0 +THNSL1 UCSF GRCh37 10 25313108 25313108 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 34 47 0 ENST00000376356.4:c.956G>A p.Gly319Glu p.G319E ENST00000376356 NM_024838.4 319 gGg/gAg 0 +THRAP3 UCSF GRCh37 1 36757032 36757032 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 37 60 0 ENST00000354618.5:c.1803C>T p.Asn601= p.N601= ENST00000354618 NM_005119.3 601 aaC/aaT 0 +THRSP UCSF GRCh37 11 77775109 77775109 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 39 55 0 ENST00000281030.2:c.182C>T p.Thr61Ile p.T61I ENST00000281030 NM_003251.3 61 aCc/aTc 0 +THSD1 UCSF GRCh37 13 52952735 52952735 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 47 42 0 ENST00000258613.4:c.1370C>T p.Pro457Leu p.P457L ENST00000258613 NM_018676.3 457 cCc/cTc 0 +THSD1 UCSF GRCh37 13 52952267 52952267 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 62 27 70 0 ENST00000258613.4:c.1838A>C p.Gln613Pro p.Q613P ENST00000258613 NM_018676.3 613 cAg/cCg 0 +TIMELESS UCSF GRCh37 12 56818588 56818588 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 48 25 49 0 ENST00000553532.1:c.1826C>T p.Ala609Val p.A609V ENST00000553532 609 gCt/gTt 0 +TIMELESS UCSF GRCh37 12 56815272 56815272 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 37 91 0 ENST00000553532.1:c.2731C>T p.Leu911= p.L911= ENST00000553532 911 Ctg/Ttg 0 +TJP2 UCSF GRCh37 9 71827508 71827508 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 18 66 0 ENST00000377245.4:c.105C>T p.Thr35= p.T35= ENST00000377245 NM_004817.3 35 acC/acT 0 +TLK1 UCSF GRCh37 2 171917607 171917607 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 30 32 0 ENST00000431350.2:c.390G>A p.Gln130= p.Q130= ENST00000431350 130 caG/caA 0 +TLL2 UCSF GRCh37 10 98133449 98133449 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 36 50 0 ENST00000357947.3:c.2566C>T p.Pro856Ser p.P856S ENST00000357947 NM_012465.3 856 Cca/Tca 0 +TLR9 UCSF GRCh37 3 52257979 52257979 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 50 57 0 ENST00000360658.2:c.353C>T p.Thr118Ile p.T118I ENST00000360658 NM_017442.3 118 aCc/aTc 0 +TM7SF2 UCSF GRCh37 11 64880745 64880745 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 32 14 0 ENST00000279263.7:c.358G>A p.Gly120Arg p.G120R ENST00000279263 NM_003273.3 120 Ggg/Agg 0 +TMC3 UCSF GRCh37 15 81627077 81627077 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 35 67 0 ENST00000359440.5:c.2443G>A p.Glu815Lys p.E815K ENST00000359440 NM_001080532.1 815 Gag/Aag 0 +TMCO7 UCSF GRCh37 16 69056828 69056828 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 33 55 0 ENST00000261778.1:c.2940C>T p.Asn980= p.N980= ENST00000261778 NM_024562.1 980 aaC/aaT 0 +TMED10 UCSF GRCh37 14 75614367 75614367 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 32 54 0 ENST00000303575.4:c.411G>A p.Glu137= p.E137= ENST00000303575 NM_006827.5 137 gaG/gaA 0 +TMEM102 UCSF GRCh37 17 7340310 7340310 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 20 8 0 ENST00000323206.1:c.1012G>A p.Gly338Ser p.G338S ENST00000323206 NM_178518.2 338 Ggt/Agt 0 +TMEM130 UCSF GRCh37 7 98457806 98457806 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 12 24 0 ENST00000416379.2:c.547G>A p.Asp183Asn p.D183N ENST00000416379 183 Gac/Aac 0 +TMEM132D UCSF GRCh37 12 129559485 129559485 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 43 57 0 ENST00000422113.2:c.2235C>T p.Ile745= p.I745= ENST00000422113 NM_133448.2 745 atC/atT 0 +TMEM154 UCSF GRCh37 4 153573939 153573939 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 36 75 0 ENST00000304385.3:c.205C>T p.Pro69Ser p.P69S ENST00000304385 NM_152680.2 69 Ccg/Tcg 0 +TMEM168 UCSF GRCh37 7 112424274 112424274 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 35 76 0 ENST00000312814.6:c.607C>T p.Pro203Ser p.P203S ENST00000312814 NM_001287497.1 203 Cca/Tca 0 +TMEM47 UCSF GRCh37 X 34657367 34657367 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 5 10 26 0 ENST00000275954.3:c.364G>A p.Ala122Thr p.A122T ENST00000275954 NM_031442.3 122 Gca/Aca 0 +TMEM48 UCSF GRCh37 1 54262697 54262697 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 36 66 0 ENST00000371429.3:c.1343G>A p.Gly448Glu p.G448E ENST00000371429 NM_001168551.1 448 gGg/gAg 0 +TMEM5 UCSF GRCh37 12 64202714 64202714 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 24 79 0 ENST00000261234.6:c.1174C>T p.Leu392Phe p.L392F ENST00000261234 NM_014254.2 392 Ctc/Ttc 0 +TMEM63A UCSF GRCh37 1 226062017 226062017 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 35 37 0 ENST00000366835.3:c.237C>T p.Gly79= p.G79= ENST00000366835 NM_014698.2 79 ggC/ggT 0 +TMEM63C UCSF GRCh37 14 77706066 77706066 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 10 10 0 ENST00000298351.4:c.927G>A p.Lys309= p.K309= ENST00000298351 NM_020431.2 309 aaG/aaA 0 +TMEM66 UCSF GRCh37 8 29927334 29927334 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 35 97 0 ENST00000256255.6:c.524G>A p.Gly175Glu p.G175E ENST00000256255 NM_016127.4 175 gGa/gAa 0 +TMEM67 UCSF GRCh37 8 94793962 94793962 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 22 26 0 ENST00000453321.3:c.1055G>A p.Gly352Asp p.G352D ENST00000453321 NM_153704.5 352 gGt/gAt 0 +TMEM8A UCSF GRCh37 16 422611 422611 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 70 46 0 ENST00000431232.2:c.2019G>A p.Trp673Ter p.W673* ENST00000431232 NM_021259.2 673 tgG/tgA 0 +TMIGD1 UCSF GRCh37 17 28652071 28652071 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 57 89 0 ENST00000328886.4:c.403G>A p.Glu135Lys p.E135K ENST00000328886 NM_206832.1 135 Gaa/Aaa 0 +TMIGD2 UCSF GRCh37 19 4297985 4297985 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 89 79 0 ENST00000301272.2:c.404C>T p.Pro135Leu p.P135L ENST00000301272 NM_144615.2 135 cCa/cTa 0 +TMOD4 UCSF GRCh37 1 151146957 151146957 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 147 76 106 0 ENST00000295314.4:c.190G>A p.Asp64Asn p.D64N ENST00000295314 NM_013353.2 64 Gac/Aac 0 +TMPRSS11D UCSF GRCh37 4 68703921 68703921 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 33 55 0 ENST00000283916.6:c.444C>T p.Asn148= p.N148= ENST00000283916 NM_004262.2 148 aaC/aaT 0 +TMPRSS15 UCSF GRCh37 21 19744516 19744516 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 45 23 51 0 ENST00000284885.3:c.658A>C p.Met220Leu p.M220L ENST00000284885 NM_002772.2 220 Atg/Ctg 0 +TMPRSS7 UCSF GRCh37 3 111797718 111797718 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 37 59 0 ENST00000452346.2:c.2354C>T p.Ala785Val p.A785V ENST00000452346 785 gCc/gTc 0 +TMX3 UCSF GRCh37 18 66364480 66364480 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 6 9 0 ENST00000299608.2:c.553G>A p.Glu185Lys p.E185K ENST00000299608 NM_019022.3 185 Gaa/Aaa 0 +TNK1 UCSF GRCh37 17 7292202 7292202 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 13 15 0 ENST00000576812.1:c.1887G>A p.Lys629= p.K629= ENST00000576812 NM_001251902.1 629 aaG/aaA 0 +TNKS1BP1 UCSF GRCh37 11 57077016 57077016 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 77 60 0 ENST00000358252.3:c.3169G>A p.Val1057Met p.V1057M ENST00000358252 NM_033396.2 1057 Gtg/Atg 0 +TNPO2 UCSF GRCh37 19 12826505 12826505 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 31 41 0 ENST00000425528.1:c.374C>T p.Pro125Leu p.P125L ENST00000425528 125 cCc/cTc 0 +TNPO2 UCSF GRCh37 19 12814595 12814595 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 11 26 0 ENST00000425528.1:c.2043G>A p.Arg681= p.R681= ENST00000425528 681 cgG/cgA 0 +TNRC6A UCSF GRCh37 16 24801750 24801750 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 58 88 0 ENST00000395799.3:c.1787G>A p.Gly596Glu p.G596E ENST00000395799 NM_014494.2 596 gGa/gAa 0 +TNS3 UCSF GRCh37 7 47408592 47408592 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 111 40 35 1 ENST00000311160.9:c.1651C>T p.Arg551Trp p.R551W ENST00000311160 NM_022748.11 551 Cgg/Tgg 0 +TOMM7 UCSF GRCh37 7 22862346 22862346 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 197 64 75 0 ENST00000358435.4:c.53G>A p.Gly18Glu p.G18E ENST00000358435 NM_019059.3 18 gGg/gAg 0 +TONSL UCSF GRCh37 8 145661746 145661746 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 32 27 0 ENST00000409379.3:c.2070G>A p.Glu690= p.E690= ENST00000409379 NM_013432.4 690 gaG/gaA 0 +TOP1 UCSF GRCh37 20 39729897 39729897 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 46 77 0 ENST00000361337.2:c.1212C>T p.Val404= p.V404= ENST00000361337 NM_003286.2 404 gtC/gtT 0 +TOP1MT UCSF GRCh37 8 144403488 144403488 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 28 16 0 ENST00000329245.4:c.1029C>T p.Leu343= p.L343= ENST00000329245 NM_052963.2 343 ctC/ctT 0 +TOP2B UCSF GRCh37 3 25650771 25650771 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 16 35 0 ENST00000264331.4:c.3996G>A p.Arg1332= p.R1332= ENST00000264331 1332 cgG/cgA 0 +TP53 UCSF GRCh37 17 7578211 7578211 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 41 23 46 0 ENST00000269305.4:c.638G>C p.Arg213Pro p.R213P ENST00000269305 NM_001126112.2 213 cGa/cCa 0 +TP53 UCSF GRCh37 17 7578275 7578275 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 46 31 43 0 ENST00000269305.4:c.574C>T p.Gln192Ter p.Q192* ENST00000269305 NM_001126112.2 192 Cag/Tag 0 +TP53BP2 UCSF GRCh37 1 223971997 223971997 + synonymous_variant Silent SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 11 84 0 ENST00000343537.7:c.3183C>A p.Gly1061= p.G1061= ENST00000343537 NM_001031685.2 1061 ggC/ggA 0 +TP53I13 UCSF GRCh37 17 27898940 27898940 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 65 67 0 ENST00000301057.7:c.378C>T p.Ala126= p.A126= ENST00000301057 NM_138349.2 126 gcC/gcT 0 +TP53INP1 UCSF GRCh37 8 95953109 95953109 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 38 60 0 ENST00000342697.4:c.61C>T p.Pro21Ser p.P21S ENST00000342697 NM_033285.3 21 Cca/Tca 0 +TP63 UCSF GRCh37 3 189587118 189587118 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 16 45 0 ENST00000264731.3:c.1135C>T p.Arg379Cys p.R379C ENST00000264731 NM_003722.4 379 Cgt/Tgt 0 +TPM3 UCSF GRCh37 1 154164488 154164488 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 43 84 0 ENST00000368530.2:c.7G>A p.Glu3Lys p.E3K ENST00000368530 NM_152263.3 3 Gag/Aag 0 +TPM3 UCSF GRCh37 1 154163740 154163740 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 31 82 0 ENST00000368530.2:c.165G>A p.Glu55= p.E55= ENST00000368530 NM_152263.3 55 gaG/gaA 0 +TPR UCSF GRCh37 1 186331971 186331971 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 31 45 0 ENST00000367478.4:c.694G>A p.Glu232Lys p.E232K ENST00000367478 NM_003292.2 232 Gag/Aag 0 +TPTE UCSF GRCh37 21 10907015 10907015 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 132 20 75 0 ENST00000361285.4:c.1546G>A p.Asp516Asn p.D516N ENST00000361285 NM_199261.2 516 Gat/Aat 0 +TRAF3 UCSF GRCh37 14 103371743 103371743 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 104 12 40 0 ENST00000392745.2:c.1329G>A p.Gln443= p.Q443= ENST00000392745 443 caG/caA 0 +TRAM1L1 UCSF GRCh37 4 118006308 118006308 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 49 56 0 ENST00000310754.4:c.242C>T p.Ala81Val p.A81V ENST00000310754 NM_152402.2 81 gCc/gTc 0 +TRDN UCSF GRCh37 6 123581772 123581772 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 19 41 0 ENST00000334268.4:c.1816G>A p.Glu606Lys p.E606K ENST00000334268 606 Gaa/Aaa 0 +TRERF1 UCSF GRCh37 6 42224797 42224797 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 41 88 0 ENST00000372922.4:c.2380C>T p.Leu794Phe p.L794F ENST00000372922 NM_033502.2 794 Ctc/Ttc 0 +TRIM16 UCSF GRCh37 17 15554749 15554749 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 88 63 0 ENST00000336708.7:c.175G>A p.Asp59Asn p.D59N ENST00000336708 NM_006470.3 59 Gac/Aac 0 +TRIM28 UCSF GRCh37 19 59061156 59061156 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 64 69 0 ENST00000253024.5:c.2035G>A p.Asp679Asn p.D679N ENST00000253024 NM_005762.2 679 Gat/Aat 0 +TRIM3 UCSF GRCh37 11 6472289 6472289 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 10 16 27 0 ENST00000345851.3:c.1703C>T p.Thr568Ile p.T568I ENST00000345851 NM_033278.3 568 aCc/aTc 0 +TRIM42 UCSF GRCh37 3 140419730 140419730 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 17 43 0 ENST00000286349.3:c.2086G>A p.Val696Met p.V696M ENST00000286349 NM_152616.4 696 Gtg/Atg 0 +TRIM50 UCSF GRCh37 7 72732893 72732893 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 135 50 65 0 ENST00000333149.2:c.654C>T p.Thr218= p.T218= ENST00000333149 NM_001281450.1 218 acC/acT 0 +TRIM50 UCSF GRCh37 7 72732686 72732686 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 107 39 68 0 ENST00000333149.2:c.749G>A p.Arg250Lys p.R250K ENST00000333149 NM_001281450.1 250 aGa/aAa 0 +TRIM56 UCSF GRCh37 7 100732393 100732393 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 188 54 41 0 ENST00000306085.6:c.1800G>A p.Gly600= p.G600= ENST00000306085 NM_030961.1 600 ggG/ggA 0 +TRIM60 UCSF GRCh37 4 165962326 165962326 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 47 104 0 ENST00000341062.5:c.1102C>T p.Gln368Ter p.Q368* ENST00000341062 368 Caa/Taa 0 +TRIM67 UCSF GRCh37 1 231299572 231299572 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 9 8 0 ENST00000366653.5:c.857G>A p.Gly286Asp p.G286D ENST00000366653 286 gGc/gAc 0 +TRIOBP UCSF GRCh37 22 38121128 38121128 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 78 165 0 ENST00000406386.3:c.2565G>A p.Gln855= p.Q855= ENST00000406386 NM_001039141.2 855 caG/caA 0 +TRMT12 UCSF GRCh37 8 125463712 125463712 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 78 76 0 ENST00000328599.3:c.544G>A p.Asp182Asn p.D182N ENST00000328599 NM_017956.3 182 Gat/Aat 0 +TRPA1 UCSF GRCh37 8 72973889 72973889 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 50 83 0 ENST00000262209.4:c.915C>T p.Thr305= p.T305= ENST00000262209 NM_007332.2 305 acC/acT 0 +TRPC3 UCSF GRCh37 4 122853901 122853901 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 98 82 33 0 ENST00000379645.3:c.512A>C p.Asn171Thr p.N171T ENST00000379645 NM_001130698.1 171 aAc/aCc 0 +TRPM2 UCSF GRCh37 21 45815341 45815341 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 35 67 0 ENST00000300482.5:c.1839C>T p.Gly613= p.G613= ENST00000300482 613 ggC/ggT 0 +TRPM3 UCSF GRCh37 9 73376591 73376591 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 35 37 55 0 ENST00000377110.3:c.1198A>G p.Thr400Ala p.T400A ENST00000377110 400 Act/Gct 0 +TRPM3 UCSF GRCh37 9 73426129 73426129 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 22 19 0 ENST00000377110.3:c.973+16634C>T *325* ENST00000377110 0 +TRPM6 UCSF GRCh37 9 77400854 77400854 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 151 41 108 0 ENST00000360774.1:c.2855G>A p.Arg952Gln p.R952Q ENST00000360774 NM_017662.4 952 cGg/cAg 0 +TRPM6 UCSF GRCh37 9 77418721 77418721 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 97 52 94 0 ENST00000360774.1:c.1720T>C p.Tyr574His p.Y574H ENST00000360774 NM_017662.4 574 Tac/Cac 0 +TRPV2 UCSF GRCh37 17 16320991 16320991 + synonymous_variant Silent SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 54 21 49 0 ENST00000338560.7:c.9A>C p.Ser3= p.S3= ENST00000338560 NM_016113.4 3 tcA/tcC 0 +TRRAP UCSF GRCh37 7 98579453 98579453 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 17 11 13 0 ENST00000359863.4:c.8675C>T p.Ala2892Val p.A2892V ENST00000359863 NM_001244580.1 2892 gCc/gTc 0 +TSGA10IP UCSF GRCh37 11 65721163 65721163 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 42 32 0 ENST00000532620.1:n.1508G>A *503* ENST00000532620 0 +TSHZ2 UCSF GRCh37 20 51871740 51871740 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 78 107 0 ENST00000371497.5:c.1743G>A p.Lys581= p.K581= ENST00000371497 NM_173485.5 581 aaG/aaA 0 +TSHZ3 UCSF GRCh37 19 31768537 31768537 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 42 49 0 ENST00000240587.4:c.2162C>T p.Pro721Leu p.P721L ENST00000240587 NM_020856.2 721 cCt/cTt 0 +TSPAN12 UCSF GRCh37 7 120428745 120428745 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 237 123 118 0 ENST00000222747.3:c.819T>C p.Cys273= p.C273= ENST00000222747 NM_012338.3 273 tgT/tgC 0 +TSSK3 UCSF GRCh37 1 32829360 32829360 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 38 50 0 ENST00000373534.3:c.310G>A p.Gly104Arg p.G104R ENST00000373534 NM_052841.3 104 Ggg/Agg 0 +TTBK1 UCSF GRCh37 6 43220535 43220535 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 23 44 0 ENST00000259750.4:c.167C>T p.Thr56Ile p.T56I ENST00000259750 NM_032538.1 56 aCc/aTc 0 +TTC21B UCSF GRCh37 2 166747022 166747022 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 33 41 0 ENST00000243344.7:c.3230G>A p.Gly1077Asp p.G1077D ENST00000243344 NM_024753.4 1077 gGt/gAt 0 +TTC3 UCSF GRCh37 21 38572625 38572625 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 17 34 0 ENST00000354749.2:c.5943G>A p.Gly1981= p.G1981= ENST00000354749 1981 ggG/ggA 0 +TTC37 UCSF GRCh37 5 94852056 94852056 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 21 43 0 ENST00000358746.2:c.2634+1G>A p.X878_splice ENST00000358746 NM_014639.3 0 +TTC7A UCSF GRCh37 2 47205951 47205951 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 63 125 0 ENST00000319190.5:c.669G>A p.Ser223= p.S223= ENST00000319190 NM_020458.2 223 tcG/tcA 0 +TTC7A UCSF GRCh37 2 47222302 47222302 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 17 53 0 ENST00000319190.5:c.1029G>A p.Glu343= p.E343= ENST00000319190 NM_020458.2 343 gaG/gaA 0 +TTN UCSF GRCh37 2 179436688 179436688 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 154 74 98 0 ENST00000591111.1:c.69248C>T p.Thr23083Ile p.T23083I ENST00000591111 23083 aCt/aTt 0 +TTN UCSF GRCh37 2 179438831 179438831 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 176 92 164 0 ENST00000591111.1:c.67105C>T p.Pro22369Ser p.P22369S ENST00000591111 22369 Cca/Tca 0 +TTN UCSF GRCh37 2 179464157 179464157 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 140 106 141 0 ENST00000591111.1:c.51440C>T p.Pro17147Leu p.P17147L ENST00000591111 17147 cCa/cTa 0 +TTN UCSF GRCh37 2 179448415 179448415 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 95 45 64 0 ENST00000591111.1:c.60571T>C p.Phe20191Leu p.F20191L ENST00000591111 20191 Ttt/Ctt 0 +TTYH2 UCSF GRCh37 17 72233571 72233571 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 32 64 0 ENST00000269346.4:c.553C>T p.Leu185Phe p.L185F ENST00000269346 NM_032646.5 185 Ctc/Ttc 0 +TUBA3D UCSF GRCh37 2 132237810 132237810 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 159 48 136 0 ENST00000321253.6:c.544G>A p.Val182Met p.V182M ENST00000321253 NM_080386.3 182 Gtg/Atg 0 +TUBA8 UCSF GRCh37 22 18607059 18607059 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 22 27 0 ENST00000330423.3:c.363C>T p.Arg121= p.R121= ENST00000330423 NM_018943.2 121 cgC/cgT 0 +TUBB1 UCSF GRCh37 20 57599701 57599701 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 91 68 80 0 ENST00000217133.1:c.1219G>A p.Glu407Lys p.E407K ENST00000217133 NM_030773.3 407 Gaa/Aaa 0 +TUBB6 UCSF GRCh37 18 12325470 12325470 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 182 109 92 0 ENST00000317702.5:c.682C>T p.Leu228= p.L228= ENST00000317702 228 Ctg/Ttg 0 +TUBG1 UCSF GRCh37 17 40762482 40762482 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 20 76 0 ENST00000251413.3:c.204C>T p.Asp68= p.D68= ENST00000251413 NM_001070.4 68 gaC/gaT 0 +TUT1 UCSF GRCh37 11 62349040 62349040 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 19 27 0 ENST00000476907.1:c.407C>T p.Ser136Phe p.S136F ENST00000476907 136 tCc/tTc 0 +TUT1 UCSF GRCh37 11 62349173 62349173 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 15 14 8 0 ENST00000476907.1:c.274G>A p.Gly92Arg p.G92R ENST00000476907 92 Gga/Aga 0 +TXNDC15 UCSF GRCh37 5 134223596 134223596 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 23 32 0 ENST00000358387.4:c.315G>A p.Val105= p.V105= ENST00000358387 NM_024715.3 105 gtG/gtA 0 +TXNIP UCSF GRCh37 1 145441183 145441183 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 44 77 0 ENST00000369317.4:c.1141G>A p.Val381Met p.V381M ENST00000369317 NM_006472.4 381 Gtg/Atg 0 +TYW1B UCSF GRCh37 7 72178617 72178617 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 160 81 99 0 ENST00000435769.2:c.1333C>T p.Leu445Phe p.L445F ENST00000435769 NM_001145440.1 445 Ctt/Ttt 0 +U2SURP UCSF GRCh37 3 142739511 142739511 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 102 83 146 0 ENST00000473835.2:c.709G>A p.Asp237Asn p.D237N ENST00000473835 NM_001080415.1 237 Gat/Aat 0 +U2SURP UCSF GRCh37 3 142741787 142741787 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 41 74 0 ENST00000473835.2:c.1111G>A p.Glu371Lys p.E371K ENST00000473835 NM_001080415.1 371 Gaa/Aaa 0 +UACA UCSF GRCh37 15 70960077 70960077 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 77 120 0 ENST00000322954.6:c.2946G>A p.Lys982= p.K982= ENST00000322954 NM_018003.2 982 aaG/aaA 0 +UBA2 UCSF GRCh37 19 34957828 34957828 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 19 45 0 ENST00000246548.4:c.1650C>T p.Ala550= p.A550= ENST00000246548 NM_005499.2 550 gcC/gcT 0 +UBE2D1 UCSF GRCh37 10 60127692 60127692 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 26 65 0 ENST00000373910.4:c.314C>T p.Ser105Phe p.S105F ENST00000373910 NM_003338.4 105 tCc/tTc 0 +UBE2H UCSF GRCh37 7 129592377 129592377 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 138 52 33 0 ENST00000355621.3:c.19G>A p.Gly7Ser p.G7S ENST00000355621 NM_003344.3 7 Ggc/Agc 0 +UBE3A UCSF GRCh37 15 25616065 25616065 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 33 51 0 ENST00000397954.2:c.1265G>A p.Gly422Asp p.G422D ENST00000397954 422 gGt/gAt 0 +UBE3B UCSF GRCh37 12 109947520 109947520 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 44 62 0 ENST00000342494.3:c.1741+1G>A p.X581_splice ENST00000342494 NM_130466.3 0 +UBE3C UCSF GRCh37 7 157009665 157009665 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 23 28 0 ENST00000348165.5:c.1914G>A p.Lys638= p.K638= ENST00000348165 NM_014671.2 638 aaG/aaA 0 +UBE4A UCSF GRCh37 11 118260552 118260552 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 73 96 0 ENST00000252108.3:c.2700C>T p.Asp900= p.D900= ENST00000252108 NM_001204077.1 900 gaC/gaT 0 +UBE4B UCSF GRCh37 1 10211387 10211387 + stop_gained Nonsense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 56 37 59 0 ENST00000343090.6:c.2694C>G p.Tyr898Ter p.Y898* ENST00000343090 NM_001105562.2 898 taC/taG 0 +UBQLN4 UCSF GRCh37 1 156021538 156021538 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 25 61 0 ENST00000368309.3:c.219G>A p.Lys73= p.K73= ENST00000368309 NM_020131.3 73 aaG/aaA 0 +UBR2 UCSF GRCh37 6 42657402 42657402 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 153 80 122 0 ENST00000372899.1:c.5120G>A p.Gly1707Glu p.G1707E ENST00000372899 NM_015255.2 1707 gGa/gAa 0 +UBR4 UCSF GRCh37 1 19454142 19454142 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 77 114 0 ENST00000375254.3:c.9203C>T p.Ser3068Phe p.S3068F ENST00000375254 NM_020765.2 3068 tCt/tTt 0 +UFL1 UCSF GRCh37 6 97001376 97001376 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 15 38 0 ENST00000369278.4:c.2382G>A p.Glu794= p.E794= ENST00000369278 NM_015323.4 794 gaG/gaA 0 +UGDH UCSF GRCh37 4 39511484 39511484 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 36 37 0 ENST00000316423.6:c.707C>T p.Ser236Phe p.S236F ENST00000316423 NM_001184701.1 236 tCc/tTc 0 +UGGT1 UCSF GRCh37 2 128877945 128877945 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 104 74 101 0 ENST00000259253.6:c.888C>T p.Asp296= p.D296= ENST00000259253 NM_020120.3 296 gaC/gaT 0 +UHRF1 UCSF GRCh37 19 4954743 4954743 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 57 33 0 ENST00000592666.1:n.2615G>A *872* ENST00000592666 0 +ULK3 UCSF GRCh37 15 75132638 75132638 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 9 12 11 0 ENST00000440863.2:c.633C>T p.Pro211= p.P211= ENST00000440863 NM_001099436.1 211 ccC/ccT 0 +UMODL1 UCSF GRCh37 21 43531503 43531503 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 39 19 0 ENST00000408910.2:c.1900-113G>A *634* ENST00000408910 NM_001004416.2 0 +UPF2 UCSF GRCh37 10 11984663 11984663 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 27 49 0 ENST00000356352.2:c.3378+1G>A p.X1126_splice ENST00000356352 0 +USH2A UCSF GRCh37 1 215848163 215848163 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 27 73 0 ENST00000307340.3:c.13090C>T p.Leu4364Phe p.L4364F ENST00000307340 NM_206933.2 4364 Ctt/Ttt 0 +USP1 UCSF GRCh37 1 62910585 62910585 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 57 92 0 ENST00000339950.4:c.734G>A p.Gly245Asp p.G245D ENST00000339950 NM_003368.4 245 gGt/gAt 0 +USP2 UCSF GRCh37 11 119227929 119227929 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 6 11 11 0 ENST00000260187.2:c.1698G>A p.Gly566= p.G566= ENST00000260187 NM_004205.4 566 ggG/ggA 0 +USP24 UCSF GRCh37 1 55591413 55591413 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 56 90 0 ENST00000294383.6:c.3654G>A p.Met1218Ile p.M1218I ENST00000294383 NM_015306.2 1218 atG/atA 0 +USP24 UCSF GRCh37 1 55612626 55612626 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 160 68 117 0 ENST00000294383.6:c.2226G>A p.Gln742= p.Q742= ENST00000294383 NM_015306.2 742 caG/caA 0 +USP28 UCSF GRCh37 11 113700020 113700020 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 38 75 0 ENST00000003302.4:c.958G>A p.Val320Ile p.V320I ENST00000003302 NM_020886.2 320 Gta/Ata 0 +USP35 UCSF GRCh37 11 77907395 77907395 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 29 12 0 ENST00000529308.1:c.104G>A p.Arg35His p.R35H ENST00000529308 NM_020798.2 35 cGt/cAt 0 +USP35 UCSF GRCh37 11 77921413 77921413 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 157 77 37 0 ENST00000529308.1:c.2512G>A p.Ala838Thr p.A838T ENST00000529308 NM_020798.2 838 Gct/Act 0 +USP37 UCSF GRCh37 2 219319679 219319679 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 49 82 0 ENST00000258399.3:c.2914G>A p.Gly972Arg p.G972R ENST00000258399 NM_020935.2 972 Ggg/Agg 0 +USP46 UCSF GRCh37 4 53492238 53492238 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 215 27 107 0 ENST00000441222.3:c.508G>A p.Glu170Lys p.E170K ENST00000441222 NM_022832.3 170 Gag/Aag 0 +USP6 UCSF GRCh37 17 5073988 5073988 + synonymous_variant Silent SNP C C T snp132_rs16964010 P05_Rec Untested WXS Illumina HiSeq 104 74 148 0 ENST00000250066.6:c.3732C>T p.Ser1244= p.S1244= ENST00000250066 NM_004505.2 1244 agC/agT 0 +USP6NL UCSF GRCh37 10 11523793 11523793 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 127 69 134 0 ENST00000609104.1:c.1054G>A p.Ala352Thr p.A352T ENST00000609104 NM_014688.2 352 Gca/Aca 0 +USPL1 UCSF GRCh37 13 31227426 31227426 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 67 95 0 ENST00000255304.4:c.1380G>A p.Trp460Ter p.W460* ENST00000255304 NM_005800.4 460 tgG/tgA 0 +UTRN UCSF GRCh37 6 144863953 144863953 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 9 14 0 ENST00000367545.3:c.6542C>T p.Thr2181Ile p.T2181I ENST00000367545 NM_007124.2 2181 aCc/aTc 0 +VARS2 UCSF GRCh37 6 30890318 30890318 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 56 91 0 ENST00000321897.5:c.2024G>A p.Gly675Glu p.G675E ENST00000321897 675 gGg/gAg 0 +VAV2 UCSF GRCh37 9 136635609 136635609 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 46 33 0 ENST00000371850.3:c.2238C>T p.Tyr746= p.Y746= ENST00000371850 NM_001134398.1 746 taC/taT 0 +VIL1 UCSF GRCh37 2 219300072 219300072 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 14 31 0 ENST00000248444.5:c.1741G>A p.Glu581Lys p.E581K ENST00000248444 NM_007127.2 581 Gag/Aag 0 +VIPAR UCSF GRCh37 14 77917622 77917622 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 74 126 0 ENST00000343765.2:c.251G>A p.Gly84Glu p.G84E ENST00000343765 84 gGg/gAg 0 +VIPAR UCSF GRCh37 14 77920421 77920421 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 27 54 0 ENST00000343765.2:c.25G>A p.Glu9Lys p.E9K ENST00000343765 9 Gag/Aag 0 +VMO1 UCSF GRCh37 17 4689213 4689213 + intron_variant Intron SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 65 83 0 ENST00000328739.5:c.311+19G>A *104* ENST00000328739 NM_182566.2 0 +VN1R5 UCSF GRCh37 1 247420069 247420069 + non_coding_transcript_exon_variant RNA SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 113 76 165 0 ENST00000472952.2:n.696T>C *232* ENST00000472952 0 +VPS11 UCSF GRCh37 11 118938649 118938649 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 51 36 0 ENST00000300793.6:c.115G>A p.Ala39Thr p.A39T ENST00000300793 NM_021729.4 39 Gct/Act 0 +VPS11 UCSF GRCh37 11 118950010 118950010 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 16 37 0 ENST00000300793.6:c.2435G>A p.Ser812Asn p.S812N ENST00000300793 NM_021729.4 812 aGt/aAt 0 +VPS13B UCSF GRCh37 8 100866404 100866404 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 37 53 0 ENST00000358544.2:c.10862G>A p.Arg3621Lys p.R3621K ENST00000358544 NM_017890.4 3621 aGa/aAa 0 +VPS13B UCSF GRCh37 8 100523518 100523518 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 51 86 0 ENST00000358544.2:c.4486G>A p.Ala1496Thr p.A1496T ENST00000358544 NM_017890.4 1496 Gca/Aca 0 +VPS13C UCSF GRCh37 15 62269303 62269303 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 33 43 0 ENST00000261517.5:c.2386G>A p.Glu796Lys p.E796K ENST00000261517 NM_020821.2 796 Gaa/Aaa 0 +VPS8 UCSF GRCh37 3 184742165 184742165 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 31 63 0 ENST00000437079.3:c.4044C>T p.Pro1348= p.P1348= ENST00000437079 NM_001009921.2 1348 ccC/ccT 0 +VWA5B2 UCSF GRCh37 3 183959043 183959043 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 19 9 0 ENST00000426955.2:c.3031G>A p.Gly1011Arg p.G1011R ENST00000426955 NM_138345.1 1011 Ggg/Agg 0 +WAPAL UCSF GRCh37 10 88203119 88203119 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 30 72 0 ENST00000298767.5:c.3324C>T p.Ala1108= p.A1108= ENST00000298767 NM_015045.2 1108 gcC/gcT 0 +WDFY3 UCSF GRCh37 4 85716108 85716108 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 18 31 0 ENST00000295888.4:c.3192C>T p.Ala1064= p.A1064= ENST00000295888 NM_014991.4 1064 gcC/gcT 0 +WDR24 UCSF GRCh37 16 739343 739343 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 44 25 0 ENST00000248142.6:c.484G>A p.Val162Ile p.V162I ENST00000248142 162 Gtc/Atc 0 +WDR3 UCSF GRCh37 1 118483801 118483801 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 35 70 0 ENST00000349139.5:c.844G>A p.Val282Ile p.V282I ENST00000349139 NM_006784.2 282 Gtt/Att 0 +WDR44 UCSF GRCh37 X 117532428 117532428 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 28 83 0 ENST00000254029.3:c.1269G>A p.Gln423= p.Q423= ENST00000254029 NM_019045.4 423 caG/caA 0 +WDR47 UCSF GRCh37 1 109553812 109553812 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.00091 P05_Rec Untested WXS Illumina HiSeq 247 157 208 0 ENST00000369962.3:c.856C>T p.Pro286Ser p.P286S ENST00000369962 286 Cct/Tct 0 +WDR49 UCSF GRCh37 3 167293884 167293884 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 45 60 0 ENST00000308378.3:c.308C>T p.Ser103Phe p.S103F ENST00000308378 NM_178824.3 103 tCt/tTt 0 +WDR52 UCSF GRCh37 3 113082355 113082355 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 15 26 0 ENST00000295868.2:c.2740C>T p.Pro914Ser p.P914S ENST00000295868 NM_018338.3 914 Cca/Tca 0 +WDR60 UCSF GRCh37 7 158715093 158715093 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 320 76 179 0 ENST00000407559.3:c.1947C>T p.Thr649= p.T649= ENST00000407559 NM_018051.4 649 acC/acT 0 +WDR65 UCSF GRCh37 1 43685208 43685208 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 36 63 0 ENST00000372492.4:c.2247G>A p.Gln749= p.Q749= ENST00000372492 NM_001195831.2 749 caG/caA 0 +WDR7 UCSF GRCh37 18 54362355 54362355 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 61 94 0 ENST00000254442.3:c.1283G>A p.Gly428Glu p.G428E ENST00000254442 NM_015285.2 428 gGa/gAa 0 +WDR72 UCSF GRCh37 15 53908093 53908093 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 126 68 132 0 ENST00000360509.5:c.2310G>A p.Lys770= p.K770= ENST00000360509 770 aaG/aaA 0 +WDR75 UCSF GRCh37 2 190327356 190327356 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 52 91 0 ENST00000314761.4:c.925C>T p.His309Tyr p.H309Y ENST00000314761 NM_032168.1 309 Cac/Tac 0 +WDR87 UCSF GRCh37 19 38378524 38378524 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 61 66 0 ENST00000303868.5:c.5670G>A p.Gln1890= p.Q1890= ENST00000303868 NM_031951.3 1890 caG/caA 0 +WDR90 UCSF GRCh37 16 716093 716093 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 54 33 0 ENST00000293879.4:c.4578G>A p.Val1526= p.V1526= ENST00000293879 1526 gtG/gtA 0 +WDR92 UCSF GRCh37 2 68361836 68361836 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 24 48 0 ENST00000295121.6:c.864G>A p.Lys288= p.K288= ENST00000295121 NM_138458.3 288 aaG/aaA 0 +WHSC1 UCSF GRCh37 4 1956990 1956990 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 35 34 0 ENST00000382891.5:c.2441C>T p.Thr814Ile p.T814I ENST00000382891 NM_133335.3 814 aCt/aTt 0 +WIPF3 UCSF GRCh37 7 29918679 29918679 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 161 32 67 0 ENST00000242140.5:c.278G>A p.Ser93Asn p.S93N ENST00000242140 93 aGc/aAc 0 +WISP1 UCSF GRCh37 8 134239825 134239825 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 50 77 0 ENST00000250160.6:c.976G>A p.Asp326Asn p.D326N ENST00000250160 NM_003882.3 326 Gat/Aat 0 +WNK1 UCSF GRCh37 12 970338 970338 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 279 90 132 0 ENST00000315939.6:c.1780G>A p.Glu594Lys p.E594K ENST00000315939 NM_018979.3 594 Gaa/Aaa 0 +WNT10A UCSF GRCh37 2 219746931 219746931 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 32 43 0 ENST00000258411.3:c.162G>A p.Val54= p.V54= ENST00000258411 NM_025216.2 54 gtG/gtA 0 +WNT11 UCSF GRCh37 11 75907610 75907610 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 154 18 40 0 ENST00000322563.3:c.236C>A p.Ala79Asp p.A79D ENST00000322563 NM_004626.2 79 gCc/gAc 0 +WNT2B UCSF GRCh37 1 113051913 113051913 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 8 11 0 ENST00000369684.4:c.29C>T p.Ala10Val p.A10V ENST00000369684 NM_024494.2 10 gCt/gTt 0 +WRN UCSF GRCh37 8 30921871 30921871 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 49 88 0 ENST00000298139.5:c.276G>A p.Gly92= p.G92= ENST00000298139 NM_000553.4 92 ggG/ggA 0 +WWC1 UCSF GRCh37 5 167858422 167858422 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 6 40 0 ENST00000265293.4:c.2253C>T p.Thr751= p.T751= ENST00000265293 NM_001161662.1 751 acC/acT 0 +XIRP1 UCSF GRCh37 3 39227263 39227263 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 15 8 0 ENST00000340369.3:c.3674C>T p.Thr1225Ile p.T1225I ENST00000340369 NM_194293.2 1225 aCc/aTc 0 +XPO7 UCSF GRCh37 8 21853052 21853052 + missense_variant Missense_Mutation SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 63 109 0 ENST00000252512.9:c.2287C>A p.His763Asn p.H763N ENST00000252512 NM_015024.4 763 Cat/Aat 0 +XPOT UCSF GRCh37 12 64819211 64819211 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 60 57 0 ENST00000332707.5:c.1546G>A p.Glu516Lys p.E516K ENST00000332707 NM_007235.4 516 Gaa/Aaa 0 +XRCC1 UCSF GRCh37 19 44050777 44050777 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 79 45 82 0 ENST00000262887.5:c.1396G>A p.Glu466Lys p.E466K ENST00000262887 466 Gaa/Aaa 0 +XRCC6 UCSF GRCh37 22 42046737 42046737 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 30 93 0 ENST00000359308.4:c.971G>A p.Ser324Asn p.S324N ENST00000359308 324 aGt/aAt 0 +XYLB UCSF GRCh37 3 38407160 38407160 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 29 24 0 ENST00000207870.3:c.440G>A p.Arg147His p.R147H ENST00000207870 NM_005108.3 147 cGc/cAc 0 +XYLB UCSF GRCh37 3 38420763 38420763 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 10 52 0 ENST00000207870.3:c.1221G>A p.Glu407= p.E407= ENST00000207870 NM_005108.3 407 gaG/gaA 0 +YIF1B UCSF GRCh37 19 38796082 38796082 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 12 11 0 ENST00000339413.6:c.855C>T p.Ala285= p.A285= ENST00000339413 NM_001039673.2 285 gcC/gcT 0 +YLPM1 UCSF GRCh37 14 75265287 75265287 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 35 84 0 ENST00000325680.7:c.3287G>A p.Gly1096Asp p.G1096D ENST00000325680 NM_019589.2 1096 gGt/gAt 0 +ZAN UCSF GRCh37 7 100345790 100345790 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 25 67 0 ENST00000546292.1:c.1054C>T p.Pro352Ser p.P352S ENST00000546292 NM_173059.1 352 Cca/Tca 0 +ZAN UCSF GRCh37 7 100382390 100382390 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 102 35 56 0 ENST00000546292.1:c.6765G>A p.Leu2255= p.L2255= ENST00000546292 NM_173059.1 2255 ctG/ctA 0 +ZBTB11 UCSF GRCh37 3 101384318 101384318 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 65 91 0 ENST00000312938.4:c.1113G>A p.Leu371= p.L371= ENST00000312938 NM_014415.3 371 ttG/ttA 0 +ZBTB40 UCSF GRCh37 1 22834591 22834591 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 36 24 39 0 ENST00000375647.4:c.1458G>C p.Met486Ile p.M486I ENST00000375647 NM_014870.3 486 atG/atC 0 +ZC3H14 UCSF GRCh37 14 89038484 89038484 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 31 75 0 ENST00000251038.5:c.346C>T p.Pro116Ser p.P116S ENST00000251038 NM_024824.4 116 Cca/Tca 0 +ZC3H7A UCSF GRCh37 16 11868307 11868307 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 37 76 0 ENST00000355758.4:c.688G>A p.Val230Ile p.V230I ENST00000355758 NM_014153.3 230 Gtt/Att 0 +ZC3HC1 UCSF GRCh37 7 129691065 129691065 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 31 48 0 ENST00000358303.4:c.142G>A p.Asp48Asn p.D48N ENST00000358303 NM_016478.3 48 Gac/Aac 0 +ZCCHC11 UCSF GRCh37 1 52991465 52991465 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 189 111 113 0 ENST00000371544.3:c.488G>A p.Gly163Glu p.G163E ENST00000371544 NM_015269.2 163 gGa/gAa 0 +ZCCHC14 UCSF GRCh37 16 87446357 87446357 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 192 68 74 0 ENST00000268616.4:c.1559G>A p.Ser520Asn p.S520N ENST00000268616 NM_015144.2 520 aGc/aAc 0 +ZCCHC14 UCSF GRCh37 16 87454311 87454311 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 13 20 0 ENST00000268616.4:c.441C>T p.Leu147= p.L147= ENST00000268616 NM_015144.2 147 ctC/ctT 0 +ZCCHC5 UCSF GRCh37 X 77913462 77913462 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 21 43 0 ENST00000321110.1:c.456G>A p.Glu152= p.E152= ENST00000321110 NM_152694.2 152 gaG/gaA 0 +ZCCHC8 UCSF GRCh37 12 122968055 122968055 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 154 60 82 0 ENST00000336229.4:c.557C>T p.Pro186Leu p.P186L ENST00000336229 NM_017612.3 186 cCg/cTg 0 +ZDBF2 UCSF GRCh37 2 207170065 207170065 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 143 76 95 0 ENST00000374423.3:c.813G>A p.Leu271= p.L271= ENST00000374423 NM_020923.1 271 ttG/ttA 0 +ZDHHC19 UCSF GRCh37 3 195935277 195935277 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 25 36 0 ENST00000296326.3:c.563C>T p.Ser188Phe p.S188F ENST00000296326 NM_001039617.1 188 tCc/tTc 0 +ZEB2 UCSF GRCh37 2 145157589 145157589 + stop_gained Nonsense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 150 53 80 0 ENST00000409487.3:c.1165A>T p.Lys389Ter p.K389* ENST00000409487 389 Aaa/Taa 0 +ZFAND2B UCSF GRCh37 2 220072104 220072104 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 59 47 0 ENST00000289528.5:c.111G>A p.Val37= p.V37= ENST00000289528 NM_001270999.1 37 gtG/gtA 0 +ZFAT UCSF GRCh37 8 135669891 135669891 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 17 58 0 ENST00000377838.3:c.109G>A p.Glu37Lys p.E37K ENST00000377838 NM_020863.3 37 Gaa/Aaa 0 +ZFHX2 UCSF GRCh37 14 24002825 24002825 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 150 93 106 0 ENST00000419474.3:c.1710G>A p.Gln570= p.Q570= ENST00000419474 NM_033400.2 570 caG/caA 0 +ZFP106 UCSF GRCh37 15 42731479 42731479 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 110 77 137 0 ENST00000263805.4:c.4227G>A p.Glu1409= p.E1409= ENST00000263805 NM_022473.1 1409 gaG/gaA 0 +ZFP37 UCSF GRCh37 9 115805715 115805715 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 65 138 0 ENST00000374227.3:c.1183C>T p.His395Tyr p.H395Y ENST00000374227 395 Cat/Tat 0 +ZFP90 UCSF GRCh37 16 68597932 68597932 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 111 46 77 0 ENST00000398253.2:c.1242G>A p.Arg414= p.R414= ENST00000398253 NM_133458.2 414 agG/agA 0 +ZFPM2 UCSF GRCh37 8 106814052 106814052 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 213 120 228 0 ENST00000407775.2:c.1742C>T p.Ser581Phe p.S581F ENST00000407775 NM_012082.3 581 tCc/tTc 0 +ZFR UCSF GRCh37 5 32385715 32385715 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 91 49 67 0 ENST00000265069.8:c.2540C>T p.Ser847Phe p.S847F ENST00000265069 NM_016107.3 847 tCt/tTt 0 +ZFR2 UCSF GRCh37 19 3823333 3823333 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 38 51 0 ENST00000262961.4:c.1282G>A p.Gly428Ser p.G428S ENST00000262961 NM_015174.1 428 Ggt/Agt 0 +ZFR2 UCSF GRCh37 19 3823340 3823340 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 35 48 0 ENST00000262961.4:c.1275A>T p.Lys425Asn p.K425N ENST00000262961 NM_015174.1 425 aaA/aaT 0 +ZGPAT UCSF GRCh37 20 62340026 62340026 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 37 10 0 ENST00000328969.5:c.94G>A p.Glu32Lys p.E32K ENST00000328969 NM_032527.4 32 Gag/Aag 0 +ZIK1 UCSF GRCh37 19 58096347 58096347 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 40 47 0 ENST00000597850.1:c.61G>A p.Asp21Asn p.D21N ENST00000597850 NM_001010879.2 21 Gac/Aac 0 +ZMAT5 UCSF GRCh37 22 30136704 30136704 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 7 13 10 0 ENST00000344318.3:c.206G>A p.Gly69Asp p.G69D ENST00000344318 NM_001003692.1 69 gGc/gAc 0 +ZMYM5 UCSF GRCh37 13 20426330 20426330 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 158 84 160 0 ENST00000337963.4:c.-10G>A p.X4_splice ENST00000337963 NM_001142684.1 0 +ZNF192 UCSF GRCh37 6 28116513 28116513 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 79 74 95 0 ENST00000330236.6:c.328C>T p.Leu110= p.L110= ENST00000330236 NM_001278122.1 110 Ctg/Ttg 0 +ZNF212 UCSF GRCh37 7 148947384 148947384 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 166 85 87 0 ENST00000335870.2:c.159G>A p.Lys53= p.K53= ENST00000335870 NM_012256.3 53 aaG/aaA 0 +ZNF217 UCSF GRCh37 20 52193739 52193739 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 65 82 0 ENST00000302342.3:c.1564C>T p.His522Tyr p.H522Y ENST00000302342 NM_006526.2 522 Cac/Tac 0 +ZNF276 UCSF GRCh37 16 89793686 89793686 + splice_acceptor_variant Splice_Site SNP G G A snp132_rs35924380 P05_Rec Untested WXS Illumina HiSeq 93 33 49 0 ENST00000443381.2:c.1007-1G>A p.X336_splice ENST00000443381 NM_001113525.1 0 +ZNF282 UCSF GRCh37 7 148895596 148895596 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 133 64 51 0 ENST00000262085.3:c.337G>A p.Asp113Asn p.D113N ENST00000262085 NM_003575.2 113 Gat/Aat 0 +ZNF287 UCSF GRCh37 17 16456380 16456380 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 60 96 0 ENST00000395824.1:c.1076G>A p.Arg359Lys p.R359K ENST00000395824 359 aGg/aAg 0 +ZNF319 UCSF GRCh37 16 58031145 58031145 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 126 50 31 0 ENST00000299237.2:c.1025C>T p.Pro342Leu p.P342L ENST00000299237 NM_020807.1 342 cCc/cTc 0 +ZNF323 UCSF GRCh37 6 28297340 28297340 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 120 69 102 0 ENST00000344279.6:c.121C>T p.Leu41Phe p.L41F ENST00000344279 41 Ctt/Ttt 0 +ZNF324 UCSF GRCh37 19 58982849 58982849 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 13 37 33 0 ENST00000196482.3:c.990G>A p.Arg330= p.R330= ENST00000196482 NM_014347.2 330 cgG/cgA 0 +ZNF333 UCSF GRCh37 19 14827864 14827864 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 13 7 12 0 ENST00000292530.6:c.786G>A p.Trp262Ter p.W262* ENST00000292530 NM_032433.2 262 tgG/tgA 0 +ZNF335 UCSF GRCh37 20 44587967 44587967 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 43 30 0 ENST00000322927.2:c.2126G>A p.Gly709Glu p.G709E ENST00000322927 NM_022095.3 709 gGg/gAg 0 +ZNF337 UCSF GRCh37 20 25657391 25657391 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 85 168 0 ENST00000252979.5:c.533G>A p.Gly178Glu p.G178E ENST00000252979 NM_015655.2 178 gGa/gAa 0 +ZNF35 UCSF GRCh37 3 44701118 44701118 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.011,1000g2011may_all_0.0223,snp132_rs116792244 P05_Rec Untested WXS Illumina HiSeq 73 29 44 0 ENST00000396056.2:c.1263C>T p.Ser421= p.S421= ENST00000396056 NM_003420.3 421 agC/agT 0 +ZNF394 UCSF GRCh37 7 99092124 99092124 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 122 53 92 0 ENST00000337673.6:c.714C>T p.Thr238= p.T238= ENST00000337673 NM_032164.2 238 acC/acT 0 +ZNF407 UCSF GRCh37 18 72347340 72347340 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 65 85 0 ENST00000299687.5:c.4365C>T p.Thr1455= p.T1455= ENST00000299687 NM_017757.2 1455 acC/acT 0 +ZNF415 UCSF GRCh37 19 53612377 53612377 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 38 78 0 ENST00000500065.4:c.921G>A p.Lys307= p.K307= ENST00000500065 NM_001136038.2 307 aaG/aaA 0 +ZNF441 UCSF GRCh37 19 11890937 11890937 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 46 100 0 ENST00000357901.4:c.298G>A p.Val100Ile p.V100I ENST00000357901 NM_152355.2 100 Gta/Ata 0 +ZNF441 UCSF GRCh37 19 11891501 11891501 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 134 61 135 0 ENST00000357901.4:c.862G>A p.Ala288Thr p.A288T ENST00000357901 NM_152355.2 288 Gca/Aca 0 +ZNF442 UCSF GRCh37 19 12461660 12461660 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 204 123 241 0 ENST00000242804.4:c.739C>T p.Pro247Ser p.P247S ENST00000242804 NM_030824.2 247 Cct/Tct 0 +ZNF467 UCSF GRCh37 7 149467538 149467538 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 16 30 0 ENST00000302017.3:c.142G>A p.Val48Met p.V48M ENST00000302017 NM_207336.1 48 Gtg/Atg 0 +ZNF467 UCSF GRCh37 7 149462662 149462662 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 10 8 0 ENST00000302017.3:c.929C>T p.Thr310Met p.T310M ENST00000302017 NM_207336.1 310 aCg/aTg 0 +ZNF48 UCSF GRCh37 16 30409098 30409098 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 46 36 0 ENST00000320159.2:c.527G>A p.Gly176Asp p.G176D ENST00000320159 NM_152652.2 176 gGt/gAt 0 +ZNF490 UCSF GRCh37 19 12692278 12692278 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 120 60 133 0 ENST00000311437.6:c.611C>T p.Thr204Ile p.T204I ENST00000311437 NM_020714.2 204 aCt/aTt 0 +ZNF490 UCSF GRCh37 19 12692468 12692468 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 60 99 0 ENST00000311437.6:c.421C>T p.Pro141Ser p.P141S ENST00000311437 NM_020714.2 141 Cct/Tct 0 +ZNF506 UCSF GRCh37 19 19917874 19917874 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 159 95 135 0 ENST00000443905.2:c.7C>T p.Pro3Ser p.P3S ENST00000443905 3 Cca/Tca 0 +ZNF532 UCSF GRCh37 18 56651271 56651271 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 48 80 0 ENST00000336078.4:c.3479C>T p.Thr1160Ile p.T1160I ENST00000336078 NM_018181.4 1160 aCt/aTt 0 +ZNF536 UCSF GRCh37 19 30936483 30936483 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 54 21 0 ENST00000355537.3:c.2014C>T p.Arg672Cys p.R672C ENST00000355537 NM_014717.1 672 Cgt/Tgt 0 +ZNF536 UCSF GRCh37 19 30935391 30935391 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 184 93 67 0 ENST00000355537.3:c.922G>A p.Ala308Thr p.A308T ENST00000355537 NM_014717.1 308 Gcg/Acg 0 +ZNF541 UCSF GRCh37 19 48047518 48047518 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 28 14 0 ENST00000391901.3:c.2268C>T p.Gly756= p.G756= ENST00000391901 NM_001277075.1 756 ggC/ggT 0 +ZNF554 UCSF GRCh37 19 2834574 2834574 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 25 75 0 ENST00000317243.5:c.1341C>T p.Asp447= p.D447= ENST00000317243 NM_001102651.1 447 gaC/gaT 0 +ZNF557 UCSF GRCh37 19 7083018 7083018 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 35 81 0 ENST00000414706.1:c.556G>A p.Gly186Arg p.G186R ENST00000414706 NM_024341.2 186 Ggg/Agg 0 +ZNF560 UCSF GRCh37 19 9577475 9577475 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 63 153 0 ENST00000301480.4:c.2148C>T p.Asp716= p.D716= ENST00000301480 NM_152476.2 716 gaC/gaT 0 +ZNF561 UCSF GRCh37 19 9727769 9727769 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 62 144 0 ENST00000302851.3:c.193C>T p.Leu65Phe p.L65F ENST00000302851 NM_152289.2 65 Ctc/Ttc 0 +ZNF585B UCSF GRCh37 19 37677650 37677650 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 146 83 137 0 ENST00000532828.2:c.789C>T p.Ile263= p.I263= ENST00000532828 NM_152279.3 263 atC/atT 0 +ZNF615 UCSF GRCh37 19 52497163 52497163 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 41 78 0 ENST00000376716.5:c.1166C>T p.Thr389Ile p.T389I ENST00000376716 NM_198480.3 389 aCa/aTa 0 +ZNF620 UCSF GRCh37 3 40557693 40557693 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 28 69 0 ENST00000314529.6:c.608G>A p.Arg203Lys p.R203K ENST00000314529 NM_175888.3 203 aGa/aAa 0 +ZNF620 UCSF GRCh37 3 40557846 40557846 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 33 88 0 ENST00000314529.6:c.761G>A p.Cys254Tyr p.C254Y ENST00000314529 NM_175888.3 254 tGt/tAt 0 +ZNF624 UCSF GRCh37 17 16527505 16527505 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 56 76 0 ENST00000311331.7:c.695C>T p.Thr232Ile p.T232I ENST00000311331 NM_020787.3 232 aCa/aTa 0 +ZNF626 UCSF GRCh37 19 20829188 20829188 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 162 99 165 0 ENST00000601440.1:c.27G>A p.Val9= p.V9= ENST00000601440 NM_001076675.2 9 gtG/gtA 0 +ZNF644 UCSF GRCh37 1 91404482 91404482 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 45 95 0 ENST00000337393.5:c.2429G>A p.Arg810Lys p.R810K ENST00000337393 NM_201269.2 810 aGa/aAa 0 +ZNF648 UCSF GRCh37 1 182026564 182026564 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 23 15 0 ENST00000339948.3:c.582G>A p.Arg194= p.R194= ENST00000339948 NM_001009992.1 194 agG/agA 0 +ZNF648 UCSF GRCh37 1 182026690 182026690 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 39 45 0 ENST00000339948.3:c.456C>T p.Tyr152= p.Y152= ENST00000339948 NM_001009992.1 152 taC/taT 0 +ZNF653 UCSF GRCh37 19 11597911 11597911 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 45 46 0 ENST00000293771.5:c.1234G>A p.Ala412Thr p.A412T ENST00000293771 NM_138783.3 412 Gca/Aca 0 +ZNF707 UCSF GRCh37 8 144773782 144773782 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 16 18 0 ENST00000358656.4:c.155C>T p.Pro52Leu p.P52L ENST00000358656 NM_001100598.1 52 cCc/cTc 0 +ZNF709 UCSF GRCh37 19 12576377 12576377 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 101 44 95 0 ENST00000397732.3:c.359A>G p.His120Arg p.H120R ENST00000397732 NM_152601.3 120 cAc/cGc 0 +ZNF729 UCSF GRCh37 19 22498434 22498434 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 147 104 115 0 ENST00000601693.1:c.2215C>T p.Pro739Ser p.P739S ENST00000601693 739 Ccc/Tcc 0 +ZNF778 UCSF GRCh37 16 89294111 89294111 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 191 79 152 0 ENST00000433976.2:c.1331C>T p.Thr444Ile p.T444I ENST00000433976 NM_001201407.1 444 aCt/aTt 0 +ZNF780A UCSF GRCh37 19 40581410 40581410 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 254 137 214 0 ENST00000340963.5:c.939C>T p.Ala313= p.A313= ENST00000340963 313 gcC/gcT 0 +ZNF813 UCSF GRCh37 19 53994800 53994800 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 102 197 0 ENST00000396403.4:c.1314C>T p.Pro438= p.P438= ENST00000396403 NM_001004301.3 438 ccC/ccT 0 +ZNF831 UCSF GRCh37 20 57767550 57767550 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 29 25 0 ENST00000371030.2:c.1476C>T p.Leu492= p.L492= ENST00000371030 NM_178457.2 492 ctC/ctT 0 +ZNF831 UCSF GRCh37 20 57829381 57829381 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 42 27 55 0 ENST00000371030.2:c.4617A>G p.Ala1539= p.A1539= ENST00000371030 NM_178457.2 1539 gcA/gcG 0 +ZNF836 UCSF GRCh37 19 52658807 52658807 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 174 96 148 0 ENST00000597252.1:c.2129C>T p.Ala710Val p.A710V ENST00000597252 710 gCa/gTa 0 +ZNF837 UCSF GRCh37 19 58879530 58879530 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 7 10 0 ENST00000427624.2:c.1170C>T p.Pro390= p.P390= ENST00000427624 390 ccC/ccT 0 +ZNF862 UCSF GRCh37 7 149558563 149558563 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 34 29 0 ENST00000223210.4:c.2314G>A p.Ala772Thr p.A772T ENST00000223210 NM_001099220.1 772 Gcg/Acg 0 +ZNHIT2 UCSF GRCh37 11 64884272 64884272 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 28 19 0 ENST00000310597.4:c.854G>A p.Gly285Glu p.G285E ENST00000310597 NM_014205.2 285 gGg/gAg 0 +ZPBP UCSF GRCh37 7 49977150 49977150 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 30 61 0 ENST00000046087.2:c.1030G>A p.Val344Met p.V344M ENST00000046087 NM_007009.2 344 Gtg/Atg 0 +ZPBP2 UCSF GRCh37 17 38028615 38028615 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 25 41 0 ENST00000348931.4:c.499C>T p.Leu167= p.L167= ENST00000348931 NM_199321.2 167 Ctg/Ttg 0 +ZSCAN10 UCSF GRCh37 16 3142594 3142594 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 12 12 0 ENST00000252463.2:c.180G>A p.Val60= p.V60= ENST00000252463 NM_032805.1 60 gtG/gtA 0 +ZSCAN21 UCSF GRCh37 7 99662011 99662011 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 22 68 0 ENST00000292450.4:c.1193G>A p.Ser398Asn p.S398N ENST00000292450 NM_145914.2 398 aGt/aAt 0 +ZSCAN5A UCSF GRCh37 19 56733035 56733035 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 61 101 0 ENST00000391713.1:c.1400C>T p.Pro467Leu p.P467L ENST00000391713 NM_024303.1 467 cCc/cTc 0 +FAM22G UCSF GRCh37 9 99697718 99697718 + synonymous_variant Silent SNP T T C snp132_rs2479289 P06_Pri Untested WXS Illumina HiSeq 24 5 27 1 ENST00000372322.3:c.822T>C p.Ile274= p.I274= ENST00000372322 NM_001170741.1 274 atT/atC 0 +GZMH UCSF GRCh37 14 25076836 25076836 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.053,snp132_rs41469548 P06_Pri Untested WXS Illumina HiSeq 28 7 53 1 ENST00000216338.4:c.321C>T p.Asn107= p.N107= ENST00000216338 NM_033423.4 107 aaC/aaT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P06_Pri Untested WXS Illumina HiSeq 40 13 45 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +RFPL1 UCSF GRCh37 22 29837847 29837847 + synonymous_variant Silent SNP G G C 1000g2010nov_all_0.077,snp132_rs61734564 P06_Pri Untested WXS Illumina HiSeq 27 6 35 1 ENST00000354373.2:c.690G>C p.Thr230= p.T230= ENST00000354373 NM_021026.2 230 acG/acC 0 +APOB UCSF GRCh37 2 21241986 21241986 + splice_acceptor_variant Splice_Site SNP C C A NOVEL P06_Rec Untested WXS Illumina HiSeq 74 9 82 0 ENST00000233242.1:c.3000-1G>T p.X1000_splice ENST00000233242 NM_000384.2 0 +ATRX UCSF GRCh37 X 76875862 76875865 + splice_donor_variant,coding_sequence_variant Splice_Site DEL CACT CACT - NOVEL P06_Rec Untested WXS Illumina HiSeq 46 0 ENST00000373344.5:c.5270_5272+1del p.X1757_splice ENST00000373344 NM_000489.3 1757 0 +CFTR UCSF GRCh37 7 117188850 117188850 + synonymous_variant Silent SNP G G T snp132_rs79074685 P06_Rec Untested WXS Illumina HiSeq 32 5 20 1 ENST00000003084.6:c.1365G>T p.Ala455= p.A455= ENST00000003084 NM_000492.3 455 gcG/gcT 0 +DNAJB4 UCSF GRCh37 1 78479131 78479131 + missense_variant Missense_Mutation SNP A A G NOVEL P06_Rec Untested WXS Illumina HiSeq 72 36 96 0 ENST00000370763.5:c.608A>G p.Glu203Gly p.E203G ENST00000370763 NM_007034.3 203 gAg/gGg 0 +DSC1 UCSF GRCh37 18 28734746 28734746 + synonymous_variant Silent SNP T T C NOVEL P06_Rec Untested WXS Illumina HiSeq 36 7 50 0 ENST00000257198.5:c.618A>G p.Glu206= p.E206= ENST00000257198 NM_024421.2 206 gaA/gaG 0 +GRIN2A UCSF GRCh37 16 9984911 9984911 + stop_gained Nonsense_Mutation SNP C C A NOVEL P06_Rec Untested WXS Illumina HiSeq 75 13 105 0 ENST00000330684.3:c.1054G>T p.Glu352Ter p.E352* ENST00000330684 NM_001134407.1 352 Gag/Tag 0 +GSN UCSF GRCh37 9 124089724 124089724 + missense_variant Missense_Mutation SNP G G A NOVEL P06_Rec Untested WXS Illumina HiSeq 8 6 10 0 ENST00000373818.4:c.1879G>A p.Ala627Thr p.A627T ENST00000373818 NM_000177.4 627 Gcc/Acc 0 +HEPHL1 UCSF GRCh37 11 93844875 93844875 + missense_variant Missense_Mutation SNP C C A NOVEL P06_Rec Untested WXS Illumina HiSeq 84 44 129 0 ENST00000315765.9:c.3295C>A p.Gln1099Lys p.Q1099K ENST00000315765 NM_001098672.1 1099 Cag/Aag 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P06_Rec Untested WXS Illumina HiSeq 29 21 45 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KLHL4 UCSF GRCh37 X 86888751 86888751 + missense_variant,splice_region_variant Missense_Mutation SNP G G T NOVEL P06_Rec Untested WXS Illumina HiSeq 27 4 28 1 ENST00000373119.4:c.1552G>T p.Val518Leu p.V518L ENST00000373119 NM_019117.4 518 Gta/Tta 0 +LARS UCSF GRCh37 5 145529208 145529208 + missense_variant Missense_Mutation SNP T T C NOVEL P06_Rec Untested WXS Illumina HiSeq 107 50 174 0 ENST00000394434.2:c.1480A>G p.Ile494Val p.I494V ENST00000394434 NM_020117.9 494 Att/Gtt 0 +LILRB1 UCSF GRCh37 19 55144532 55144532 + missense_variant Missense_Mutation SNP G G A NOVEL P06_Rec Untested WXS Illumina HiSeq 23 9 34 0 ENST00000324602.7:c.1024G>A p.Val342Met p.V342M ENST00000324602 NM_001278399.1 342 Gtg/Atg 0 +PKHD1 UCSF GRCh37 6 51612824 51612824 + missense_variant Missense_Mutation SNP T T C NOVEL P06_Rec Untested WXS Illumina HiSeq 81 40 143 0 ENST00000371117.3:c.9590A>G p.Gln3197Arg p.Q3197R ENST00000371117 NM_138694.3 3197 cAg/cGg 0 +RHOA UCSF GRCh37 3 49405899 49405899 + missense_variant Missense_Mutation SNP A A G NOVEL P06_Rec Untested WXS Illumina HiSeq 47 15 70 0 ENST00000418115.1:c.239T>C p.Ile80Thr p.I80T ENST00000418115 NM_001664.2 80 aTa/aCa 0 +SKA3 UCSF GRCh37 13 21746601 21746601 + frameshift_variant Frame_Shift_Del DEL G G - 1000g2010nov_all P06_Rec Untested WXS Illumina HiSeq 6 0 ENST00000314759.5:c.208delC p.Gln70LysfsTer7 p.Q70Kfs*7 ENST00000314759 NM_145061.5 70 Caa/aa 0 +SLC26A4 UCSF GRCh37 7 107329599 107329599 + missense_variant Missense_Mutation SNP G G A NOVEL P06_Rec Untested WXS Illumina HiSeq 46 21 80 0 ENST00000265715.3:c.1103G>A p.Gly368Glu p.G368E ENST00000265715 NM_000441.1 368 gGa/gAa 0 +SOX6 UCSF GRCh37 11 16007844 16007844 + missense_variant Missense_Mutation SNP T T C NOVEL P06_Rec Untested WXS Illumina HiSeq 99 13 101 0 ENST00000528429.1:c.2089A>G p.Thr697Ala p.T697A ENST00000528429 NM_001145819.1 697 Acc/Gcc 0 +TP53 UCSF GRCh37 17 7577120 7577120 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.000,snp132_rs28934576 P06_Rec somatic WXS Sanger Illumina HiSeq 3 18 27 0 ENST00000269305.4:c.818G>A p.Arg273His p.R273H ENST00000269305 NM_001126112.2 273 cGt/cAt 0 +UBQLNL UCSF GRCh37 11 5537008 5537008 + missense_variant Missense_Mutation SNP G G C NOVEL P06_Rec Untested WXS Illumina HiSeq 79 42 112 0 ENST00000380184.1:c.664C>G p.Leu222Val p.L222V ENST00000380184 NM_145053.4 222 Cta/Gta 0 +ULK2 UCSF GRCh37 17 19729500 19729500 + splice_acceptor_variant Splice_Site SNP C C G NOVEL P06_Rec Untested WXS Illumina HiSeq 32 23 65 0 ENST00000361658.2:c.788-1G>C p.X263_splice ENST00000361658 NM_001142610.1 0 +ZIC5 UCSF GRCh37 13 100617663 100617663 + missense_variant Missense_Mutation SNP C C T NOVEL P06_Rec Untested WXS Illumina HiSeq 21 6 21 0 ENST00000267294.4:c.1960G>A p.Gly654Arg p.G654R ENST00000267294 NM_033132.3 654 Ggg/Agg 0 +ZNF283 UCSF GRCh37 19 44352107 44352107 + missense_variant Missense_Mutation SNP A A G NOVEL P06_Rec Untested WXS Illumina HiSeq 139 57 166 0 ENST00000324461.7:c.1354A>G p.Ile452Val p.I452V ENST00000324461 NM_181845.1 452 Atc/Gtc 0 +AGAP1 UCSF GRCh37 2 237028849 237028849 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 94 13 49 0 ENST00000304032.8:c.2128C>T p.Arg710Trp p.R710W ENST00000304032 NM_001037131.2 710 Cgg/Tgg 0 +ALOX15 UCSF GRCh37 17 4542894 4542894 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.047,snp132_rs3894312 P07_Pri Untested WXS Illumina HiSeq 80 9 45 1 ENST00000293761.3:c.168T>C p.Tyr56= p.Y56= ENST00000293761 NM_001140.3 56 taT/taC 0 +ANK2 UCSF GRCh37 4 114213580 114213580 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 12 5 19 0 ENST00000357077.4:c.2286C>A p.Tyr762Ter p.Y762* ENST00000357077 NM_001148.4 762 taC/taA 0 +AP2A2 UCSF GRCh37 11 1009101 1009101 + missense_variant,splice_region_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 33 20 48 1 ENST00000448903.2:c.2422T>G p.Tyr808Asp p.Y808D ENST00000448903 NM_012305.3 808 Tat/Gat 0 +ARNT UCSF GRCh37 1 150801579 150801579 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 76 13 113 0 ENST00000358595.5:c.1157A>C p.Tyr386Ser p.Y386S ENST00000358595 NM_178427.2 386 tAc/tCc 0 +ASPM UCSF GRCh37 1 197097775 197097775 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 92 16 115 0 ENST00000367409.4:c.2781G>T p.Leu927Phe p.L927F ENST00000367409 NM_018136.4 927 ttG/ttT 0 +ASPM UCSF GRCh37 1 197097791 197097791 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 66 27 100 0 ENST00000367409.4:c.2765G>A p.Ser922Asn p.S922N ENST00000367409 NM_018136.4 922 aGt/aAt 0 +ATAD3A UCSF GRCh37 1 1451415 1451415 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 38 31 64 0 ENST00000378755.5:c.229C>G p.Leu77Val p.L77V ENST00000378755 NM_018188.3 77 Ctg/Gtg 0 +ATP6V1A UCSF GRCh37 3 113508669 113508669 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 82 11 86 0 ENST00000273398.3:c.970G>A p.Glu324Lys p.E324K ENST00000273398 NM_001690.3 324 Gaa/Aaa 0 +ATRX UCSF GRCh37 X 76912145 76912145 + splice_acceptor_variant Splice_Site SNP T T C NOVEL P07_Pri somatic WXS Sanger Illumina HiSeq 41 15 56 0 ENST00000373344.5:c.4121-2A>G p.X1374_splice ENST00000373344 NM_000489.3 0 +ATRX UCSF GRCh37 X 76937485 76937485 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 78 86 83 0 ENST00000373344.5:c.3263G>C p.Gly1088Ala p.G1088A ENST00000373344 NM_000489.3 1088 gGt/gCt 0 +ATRX UCSF GRCh37 X 76937487 76937487 + stop_gained Nonsense_Mutation SNP A A T NOVEL P07_Pri Untested WXS Illumina HiSeq 77 87 83 0 ENST00000373344.5:c.3261T>A p.Tyr1087Ter p.Y1087* ENST00000373344 NM_000489.3 1087 taT/taA 0 +ATRX UCSF GRCh37 X 76937376 76937376 + synonymous_variant Silent SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 77 99 112 0 ENST00000373344.5:c.3372T>C p.Ser1124= p.S1124= ENST00000373344 NM_000489.3 1124 tcT/tcC 0 +BMF UCSF GRCh37 15 40396521 40396521 + missense_variant Missense_Mutation SNP G G A snp132_rs77642791 P07_Pri Untested WXS Illumina HiSeq 95 20 117 0 ENST00000354670.4:c.313C>T p.Pro105Ser p.P105S ENST00000354670 NM_001003940.1 105 Cct/Tct 0 +C15orf17 UCSF GRCh37 15 75194971 75194971 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 91 12 103 0 ENST00000357635.5:c.586A>C p.Thr196Pro p.T196P ENST00000357635 NM_020447.3 196 Acc/Ccc 0 +C1orf172 UCSF GRCh37 1 27276560 27276560 + stop_lost Nonstop_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 31 5 42 0 ENST00000320567.5:c.1197A>C p.Ter399TyrextTer19 p.*399Yext*19 ENST00000320567 NM_152365.2 399 taA/taC 0 +C2orf65 UCSF GRCh37 2 74787345 74787345 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri somatic WXS Sanger Illumina HiSeq 38 26 51 0 ENST00000290536.5:c.1355T>G p.Leu452Arg p.L452R ENST00000290536 NM_138804.4 452 cTg/cGg 0 +C3 UCSF GRCh37 19 6697740 6697740 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 68 10 62 0 ENST00000245907.6:c.2506C>A p.Pro836Thr p.P836T ENST00000245907 NM_000064.2 836 Ccc/Acc 0 +C8orf80 UCSF GRCh37 8 27903051 27903051 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 128 28 106 0 ENST00000413272.2:c.1439A>C p.Asn480Thr p.N480T ENST00000413272 NM_001010906.1 480 aAc/aCc 0 +CAND1 UCSF GRCh37 12 67675701 67675701 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 111 16 102 0 ENST00000545606.1:c.80C>A p.Thr27Lys p.T27K ENST00000545606 NM_018448.3 27 aCa/aAa 0 +CBLL1 UCSF GRCh37 7 107399173 107399176 + protein_altering_variant In_Frame_Del DEL ACCA ACCA C NOVEL P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000440859.3:c.1026_1029delinsC p.Pro350del p.P350del ENST00000440859 NM_024814.2 342 gcACCA/gcC 0 +CCDC27 UCSF GRCh37 1 3680383 3680383 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 20 7 41 0 ENST00000294600.2:c.1435C>A p.Gln479Lys p.Q479K ENST00000294600 NM_152492.2 479 Caa/Aaa 0 +CHRNA2 UCSF GRCh37 8 27327497 27327497 + splice_region_variant,synonymous_variant Splice_Region SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 29 19 41 1 ENST00000407991.1:c.75T>G p.Gly25= p.G25= ENST00000407991 NM_000742.3 25 ggT/ggG 0 +CNTLN UCSF GRCh37 9 17486994 17486995 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P07_Pri Untested WXS Illumina HiSeq 25 0 ENST00000380647.3:c.4054dup p.Thr1352AsnfsTer4 p.T1352Nfs*4 ENST00000380647 1350 gaa/gaAa 0 +COIL UCSF GRCh37 17 55028118 55028119 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P07_Pri Untested WXS Illumina HiSeq 7 0 ENST00000240316.4:c.485dup p.Asn162LysfsTer6 p.N162Kfs*6 ENST00000240316 NM_004645.2 162 aac/aAac 0 +COL5A1 UCSF GRCh37 9 137642705 137642705 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 13 7 20 1 ENST00000371817.3:c.1639C>A p.Gln547Lys p.Q547K ENST00000371817 NM_001278074.1 547 Caa/Aaa 0 +CPNE3 UCSF GRCh37 8 87563330 87563330 + splice_donor_variant Splice_Site SNP T T G 1000g2011may_all_0.0465 P07_Pri Untested WXS Illumina HiSeq 56 35 103 1 ENST00000198765.4:c.1068+2T>G p.X356_splice ENST00000198765 0 +CYP26B1 UCSF GRCh37 2 72359514 72359514 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 17 7 31 2 ENST00000001146.2:c.1381A>C p.Thr461Pro p.T461P ENST00000001146 NM_019885.3 461 Acc/Ccc 0 +DDX26B UCSF GRCh37 X 134703307 134703307 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 59 75 81 0 ENST00000370752.4:c.1238G>A p.Arg413Gln p.R413Q ENST00000370752 NM_182540.4 413 cGa/cAa 0 +DEFB126 UCSF GRCh37 20 126310 126311 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P07_Pri Untested WXS Illumina HiSeq 9 0 ENST00000382398.3:c.313_314del p.Thr105ProfsTer? p.T105Pfs*? ENST00000382398 NM_030931.3 105 ACc/c 0 +DIXDC1 UCSF GRCh37 11 111853109 111853109 + frameshift_variant,splice_region_variant Frame_Shift_Ins INS T T CC NOVEL P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000440460.2:c.813delinsCC p.Gly272ArgfsTer44 p.G272Rfs*44 ENST00000440460 NM_001037954.3 271 ccT/ccCC 0 +DLEC1 UCSF GRCh37 3 38162039 38162040 + frameshift_variant Frame_Shift_Del DEL GA GA - 1000g2010nov_all P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000308059.6:c.4815_4816del p.Glu1605AspfsTer29 p.E1605Dfs*29 ENST00000308059 1602 gGA/g 0 +DNM1 UCSF GRCh37 9 131009679 131009679 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 22 6 24 0 ENST00000372923.3:c.1807C>G p.Leu603Val p.L603V ENST00000372923 NM_004408.2 603 Ctg/Gtg 0 +DTX2 UCSF GRCh37 7 76131644 76131644 + synonymous_variant Silent SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 47 6 18 0 ENST00000324432.5:c.1260C>T p.Ser420= p.S420= ENST00000324432 NM_020892.2 420 tcC/tcT 0 +DYRK1B UCSF GRCh37 19 40316909 40316909 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 47 11 64 0 ENST00000323039.5:c.1429T>C p.Ser477Pro p.S477P ENST00000323039 NM_004714.1 477 Tcc/Ccc 0 +EML6 UCSF GRCh37 2 55177866 55177866 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 139 23 83 1 ENST00000356458.6:c.4163A>G p.Asp1388Gly p.D1388G ENST00000356458 NM_001039753.2 1388 gAc/gGc 0 +ERAL1 UCSF GRCh37 17 27182065 27182065 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 30 6 52 0 ENST00000254928.5:c.13A>C p.Ser5Arg p.S5R ENST00000254928 NM_005702.2 5 Agc/Cgc 0 +ERBB2IP UCSF GRCh37 5 65374262 65374262 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 82 21 100 0 ENST00000284037.5:c.4143C>A p.Tyr1381Ter p.Y1381* ENST00000284037 NM_001253697.1 1381 taC/taA 0 +EXD3 UCSF GRCh37 9 140289784 140289784 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 18 4 25 0 ENST00000340951.4:c.26A>C p.Asp9Ala p.D9A ENST00000340951 NM_017820.3 9 gAc/gCc 0 +FAM53B UCSF GRCh37 10 126311912 126311912 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 16 6 37 0 ENST00000337318.3:c.1168A>G p.Arg390Gly p.R390G ENST00000337318 NM_014661.3 390 Aga/Gga 0 +FCER1A UCSF GRCh37 1 159275786 159275786 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 86 17 115 0 ENST00000368115.1:c.340C>G p.Leu114Val p.L114V ENST00000368115 NM_002001.3 114 Ctc/Gtc 0 +FLNA UCSF GRCh37 X 153579992 153579992 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 25 4 25 0 ENST00000369850.3:c.6980C>T p.Ser2327Phe p.S2327F ENST00000369850 NM_001110556.1 2327 tCt/tTt 0 +FLT4 UCSF GRCh37 5 180058762 180058762 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 22 5 29 0 ENST00000261937.6:c.75C>A p.Tyr25Ter p.Y25* ENST00000261937 NM_182925.4 25 taC/taA 0 +FMN1 UCSF GRCh37 15 33261341 33261341 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 53 39 70 1 ENST00000559047.1:c.2561T>C p.Leu854Pro p.L854P ENST00000559047 NM_001277313.1 854 cTc/cCc 0 +GCLM UCSF GRCh37 1 94354629 94354629 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 83 10 104 0 ENST00000370238.3:c.742C>A p.Leu248Met p.L248M ENST00000370238 NM_002061.2 248 Ctg/Atg 0 +GGT1 UCSF GRCh37 22 25011077 25011077 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 53 8 45 0 ENST00000248923.4:c.365C>T p.Ser122Leu p.S122L ENST00000248923 NM_013430.2 122 tCg/tTg 0 +GGT1 UCSF GRCh37 22 25011062 25011062 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.010 P07_Pri Untested WXS Illumina HiSeq 66 9 46 1 ENST00000248923.4:c.350C>G p.Thr117Ser p.T117S ENST00000248923 NM_013430.2 117 aCc/aGc 0 +GGTLC2 UCSF GRCh37 22 22988913 22988913 + missense_variant Missense_Mutation SNP T T A 1000g2011may_all_0.0159,snp132_rs71316771 P07_Pri Untested WXS Illumina HiSeq 26 6 16 0 ENST00000480559.1:c.98T>A p.Val33Asp p.V33D ENST00000480559 NM_199127.2 33 gTt/gAt 0 +GGTLC2 UCSF GRCh37 22 22988917 22988917 + synonymous_variant Silent SNP T T C 1000g2011may_all_0.0094,snp132_rs71316772 P07_Pri Untested WXS Illumina HiSeq 27 6 16 0 ENST00000480559.1:c.102T>C p.Asp34= p.D34= ENST00000480559 NM_199127.2 34 gaT/gaC 0 +GIGYF1 UCSF GRCh37 7 100285167 100285167 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri somatic WXS Sanger Illumina HiSeq 67 36 72 0 ENST00000275732.5:c.334G>C p.Ala112Pro p.A112P ENST00000275732 NM_022574.4 112 Gct/Cct 0 +GIMAP8 UCSF GRCh37 7 150167961 150167961 + missense_variant,splice_region_variant Missense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 77 26 61 0 ENST00000307271.3:c.681G>T p.Gln227His p.Q227H ENST00000307271 NM_175571.2 227 caG/caT 0 +GPHB5 UCSF GRCh37 14 63784413 63784414 + non_coding_transcript_exon_variant RNA INS - - C NOVEL P07_Pri Untested WXS Illumina HiSeq 8 0 ENST00000314140.1:n.150_151insG *50* ENST00000314140 0 +GRXCR1 UCSF GRCh37 4 43032401 43032401 + synonymous_variant Silent SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 135 87 120 0 ENST00000399770.2:c.717T>C p.Cys239= p.C239= ENST00000399770 NM_001080476.2 239 tgT/tgC 0 +GSTP1 UCSF GRCh37 11 67352019 67352019 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 37 10 50 0 ENST00000398606.3:c.122A>G p.Glu41Gly p.E41G ENST00000398606 NM_000852.3 41 gAg/gGg 0 +HS6ST1 UCSF GRCh37 2 129025758 129025758 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.135 P07_Pri Untested WXS Illumina HiSeq 53 7 33 1 ENST00000259241.6:c.1214G>T p.Ser405Ile p.S405I ENST00000259241 NM_004807.2 405 aGc/aTc 0 +HSF1 UCSF GRCh37 8 145534883 145534883 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 21 6 28 1 ENST00000528838.1:c.512A>G p.Glu171Gly p.E171G ENST00000528838 NM_005526.2 171 gAg/gGg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 87 57 98 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGFN1 UCSF GRCh37 1 201190723 201190723 + synonymous_variant Silent SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 40 7 39 0 ENST00000295591.8:c.1530G>C p.Pro510= p.P510= ENST00000295591 510 ccG/ccC 0 +ILK UCSF GRCh37 11 6629291 6629291 + synonymous_variant Silent SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 63 13 94 0 ENST00000299421.4:c.105C>T p.Phe35= p.F35= ENST00000299421 NM_004517.3 35 ttC/ttT 0 +IPO5 UCSF GRCh37 13 98637679 98637679 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 119 20 118 0 ENST00000357602.3:c.176G>A p.Arg59Lys p.R59K ENST00000357602 59 aGa/aAa 0 +JAG2 UCSF GRCh37 14 105615535 105615535 + synonymous_variant Silent SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 40 10 36 1 ENST00000331782.3:c.1725C>G p.Arg575= p.R575= ENST00000331782 NM_002226.4 575 cgC/cgG 0 +KDM3A UCSF GRCh37 2 86678324 86678324 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 74 9 81 0 ENST00000312912.5:c.441G>A p.Leu147= p.L147= ENST00000312912 NM_018433.5 147 ttG/ttA 0 +KIAA1267 UCSF GRCh37 17 44144000 44144002 + inframe_deletion In_Frame_Del DEL GAT GAT - NOVEL P07_Pri Untested WXS Illumina HiSeq 8 0 ENST00000574590.1:c.1749_1751del p.Ser584del p.S584del ENST00000574590 NM_001193465.1 583 tcATCt/tct 0 +KIR2DL3 UCSF GRCh37 19 55263934 55263978 + stop_lost,3_prime_UTR_variant Nonstop_Mutation DEL TCATCGTGTACACGGAACTTCCAAATGCTGAGCCCTGATCCAAAG TCATCGTGTACACGGAACTTCCAAATGCTGAGCCCTGATCCAAAG CCACCATGTACATGGAACTTCCAAATGCTAAGCCAAGATCA NOVEL P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000342376.3:c.989_*7delinsCCACCATGTACATGGAACTTCCAAATGCTAAGCCAAGATCA *330* ENST00000342376 NM_015868.2 330 0 +KLHDC10 UCSF GRCh37 7 129765709 129765709 + missense_variant Missense_Mutation SNP A A T NOVEL P07_Pri Untested WXS Illumina HiSeq 71 32 20 0 ENST00000335420.5:c.869A>T p.His290Leu p.H290L ENST00000335420 NM_014997.3 290 cAt/cTt 0 +KLHL30 UCSF GRCh37 2 239049934 239049934 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 22 4 17 0 ENST00000409223.1:c.539T>G p.Val180Gly p.V180G ENST00000409223 180 gTc/gGc 0 +LAMA2 UCSF GRCh37 6 129824352 129824352 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 137 17 106 0 ENST00000421865.2:c.8474T>C p.Phe2825Ser p.F2825S ENST00000421865 NM_001079823.1 2825 tTc/tCc 0 +LRBA UCSF GRCh37 4 151935787 151935787 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 17 5 39 0 ENST00000357115.3:c.8G>A p.Ser3Asn p.S3N ENST00000357115 NM_006726.4 3 aGc/aAc 0 +LRIT2 UCSF GRCh37 10 85985269 85985269 + missense_variant Missense_Mutation SNP G G A snp132_rs79267836 P07_Pri Untested WXS Illumina HiSeq 78 19 80 0 ENST00000372113.4:c.8C>T p.Ser3Leu p.S3L ENST00000372113 NM_001017924.2 3 tCa/tTa 0 +LRP2 UCSF GRCh37 2 169993907 169993907 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 87 67 95 0 ENST00000263816.3:c.13615A>G p.Ile4539Val p.I4539V ENST00000263816 NM_004525.2 4539 Atc/Gtc 0 +MIS18BP1 UCSF GRCh37 14 45716019 45716020 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P07_Pri Untested WXS Illumina HiSeq 7 0 ENST00000310806.4:c.471dup p.Leu158IlefsTer8 p.L158Ifs*8 ENST00000310806 NM_018353.4 157 aaa/aaAa 0 +MLH3 UCSF GRCh37 14 75514620 75514623 + frameshift_variant Frame_Shift_Del DEL TCTG TCTG - NOVEL P07_Pri Untested WXS Illumina HiSeq 8 0 ENST00000355774.2:c.1736_1739del p.Thr579ArgfsTer30 p.T579Rfs*30 ENST00000355774 NM_001040108.1 579 aCAGAg/ag 0 +MMP16 UCSF GRCh37 8 89209512 89209512 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 106 12 83 0 ENST00000286614.6:c.156C>A p.Tyr52Ter p.Y52* ENST00000286614 NM_005941.4 52 taC/taA 0 +MYEF2 UCSF GRCh37 15 48443702 48443702 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 203 81 142 0 ENST00000324324.7:c.1274A>G p.Asn425Ser p.N425S ENST00000324324 NM_016132.3 425 aAt/aGt 0 +NINJ2 UCSF GRCh37 12 772656 772656 + synonymous_variant Silent SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 94 14 105 0 ENST00000305108.4:c.9T>G p.Gly3= p.G3= ENST00000305108 NM_016533.4 3 ggT/ggG 0 +NIPA1 UCSF GRCh37 15 23060899 23060899 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 17 4 36 0 ENST00000337435.4:c.233T>G p.Val78Gly p.V78G ENST00000337435 NM_144599.4 78 gTt/gGt 0 +NLGN4Y UCSF GRCh37 Y 16942197 16942197 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 35 7 74 0 ENST00000339174.5:c.1399A>C p.Thr467Pro p.T467P ENST00000339174 467 Acc/Ccc 0 +NME6 UCSF GRCh37 3 48340012 48340012 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 21 13 29 1 ENST00000415053.1:c.-6A>G p.X2_splice ENST00000415053 0 +NTF4 UCSF GRCh37 19 49564944 49564944 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 19 9 33 1 ENST00000593537.1:c.311T>G p.Val104Gly p.V104G ENST00000593537 104 gTg/gGg 0 +NVL UCSF GRCh37 1 224455754 224455754 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 49 9 57 0 ENST00000281701.6:c.2164G>C p.Ala722Pro p.A722P ENST00000281701 NM_002533.3 722 Gca/Cca 0 +OAF UCSF GRCh37 11 120099649 120099649 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 22 14 32 1 ENST00000328965.4:c.620T>G p.Val207Gly p.V207G ENST00000328965 NM_178507.2 207 gTg/gGg 0 +PIEZO1 UCSF GRCh37 16 88786118 88786118 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 20 6 37 0 ENST00000301015.9:c.6335T>G p.Val2112Gly p.V2112G ENST00000301015 NM_001142864.2 2112 gTg/gGg 0 +PKHD1 UCSF GRCh37 6 51920409 51920409 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 57 13 75 0 ENST00000371117.3:c.1812C>T p.Gly604= p.G604= ENST00000371117 NM_138694.3 604 ggC/ggT 0 +PRKDC UCSF GRCh37 8 48866910 48866910 + frameshift_variant Frame_Shift_Del DEL T T - 1000g2010nov_all P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000314191.2:c.496del p.Ile166TyrfsTer6 p.I166Yfs*6 ENST00000314191 NM_006904.6 166 Ata/ta 0 +PRSS1 UCSF GRCh37 7 142460412 142460431 + coding_sequence_variant,intron_variant In_Frame_Del DEL ATGTCAGGTGATTTGACCAA ATGTCAGGTGATTTGACCAA CTGCCAGGTGATTTGAC NOVEL P07_Pri Untested WXS Illumina HiSeq 13 0 ENST00000311737.7:c.585_591+13delinsCTGCCAGGTGATTTGAC *195* ENST00000311737 NM_002769.4 195 0 +PRSS48 UCSF GRCh37 4 152201017 152201018 + frameshift_variant Frame_Shift_Ins INS - - GGCAG NOVEL P07_Pri Untested WXS Illumina HiSeq 9 0 ENST00000455694.2:c.123_124insGCAGG p.Gln42AlafsTer23 p.Q42Afs*23 ENST00000455694 NM_183375.2 41 tgg/tgGGCAGg 0 +PTPN3 UCSF GRCh37 9 112184987 112185008 + splice_donor_variant,coding_sequence_variant,intron_variant Splice_Site INS GGAGGACATACCAGTTGGGAGT GGAGGACATACCAGTTGGGAGT AGGAGGACATACCAGGTGGGGGG NOVEL P07_Pri Untested WXS Illumina HiSeq 7 0 ENST00000374541.2:c.1126_1136+11delinsCCCCCCACCTGGTATGTCCTCCT p.X376_splice ENST00000374541 NM_001145368.1 376 0 +RANBP3L UCSF GRCh37 5 36257584 36257584 + synonymous_variant Silent SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 70 10 77 0 ENST00000296604.3:c.744G>A p.Pro248= p.P248= ENST00000296604 NM_145000.3 248 ccG/ccA 0 +RASIP1 UCSF GRCh37 19 49243416 49243416 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 38 6 48 0 ENST00000222145.4:c.124G>C p.Ala42Pro p.A42P ENST00000222145 NM_017805.2 42 Gca/Cca 0 +RCOR3 UCSF GRCh37 1 211452617 211452617 + missense_variant Missense_Mutation SNP A A T NOVEL P07_Pri Untested WXS Illumina HiSeq 105 32 92 0 ENST00000367005.4:c.505A>T p.Asn169Tyr p.N169Y ENST00000367005 NM_018254.3 169 Aat/Tat 0 +RMND5A UCSF GRCh37 2 86998675 86998684 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TAACAGATTG TAACAGATTG AACAGATTA NOVEL P07_Pri Untested WXS Illumina HiSeq 7 0 ENST00000283632.4:c.958-6_961delinsAACAGATTA p.X320_splice ENST00000283632 NM_022780.3 0 +RNF123 UCSF GRCh37 3 49728916 49728916 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 51 6 47 0 ENST00000327697.6:c.141A>C p.Glu47Asp p.E47D ENST00000327697 NM_022064.3 47 gaA/gaC 0 +ROD1 UCSF GRCh37 9 115060107 115060119 + splice_donor_variant,intron_variant Splice_Site INS CTCACCATACACA CTCACCATACACA AACCCCCATAAACC NOVEL P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000374255.2:c.118+2_118+14delinsGGTTTATGGGGGTT p.X40_splice ENST00000374255 0 +SDR42E1 UCSF GRCh37 16 82032960 82032960 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 165 62 165 0 ENST00000328945.5:c.938G>A p.Arg313His p.R313H ENST00000328945 NM_145168.2 313 cGc/cAc 0 +SEMA3A UCSF GRCh37 7 83610763 83610763 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 61 11 37 0 ENST00000265362.4:c.1526T>G p.Val509Gly p.V509G ENST00000265362 NM_006080.2 509 gTt/gGt 0 +SIGLEC12 UCSF GRCh37 19 52001516 52001516 + synonymous_variant Silent SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 49 13 82 1 ENST00000291707.3:c.1161G>C p.Ser387= p.S387= ENST00000291707 NM_053003.2 387 tcG/tcC 0 +SLC3A1 UCSF GRCh37 2 44539860 44539860 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 102 14 77 0 ENST00000260649.6:c.1468G>T p.Val490Leu p.V490L ENST00000260649 NM_000341.3 490 Gta/Tta 0 +SLC43A1 UCSF GRCh37 11 57261571 57261571 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 66 30 66 0 ENST00000278426.3:c.766A>G p.Thr256Ala p.T256A ENST00000278426 NM_003627.5 256 Acc/Gcc 0 +SLC5A10 UCSF GRCh37 17 18923739 18923739 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 52 21 65 2 ENST00000395645.3:c.1786G>C p.Ala596Pro p.A596P ENST00000395645 NM_001042450.2 596 Gcc/Ccc 0 +SLC6A18 UCSF GRCh37 5 1244398 1244398 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 63 11 59 0 ENST00000324642.3:c.1406A>G p.Glu469Gly p.E469G ENST00000324642 NM_182632.2 469 gAg/gGg 0 +SLC7A14 UCSF GRCh37 3 170244714 170244714 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 37 5 53 0 ENST00000231706.5:c.12C>T p.Phe4= p.F4= ENST00000231706 NM_020949.2 4 ttC/ttT 0 +SLC7A4 UCSF GRCh37 22 21384142 21384142 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 34 19 54 0 ENST00000382932.2:c.1481G>T p.Cys494Phe p.C494F ENST00000382932 NM_004173.2 494 tGc/tTc 0 +SMYD1 UCSF GRCh37 2 88387386 88387386 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 16 9 33 0 ENST00000419482.2:c.320C>G p.Ala107Gly p.A107G ENST00000419482 NM_198274.3 107 gCg/gGg 0 +SNAP91 UCSF GRCh37 6 84315423 84315423 + synonymous_variant Silent SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 65 14 50 0 ENST00000369694.2:c.1122A>G p.Gly374= p.G374= ENST00000369694 NM_001242792.1 374 ggA/ggG 0 +SPATA5 UCSF GRCh37 4 123850221 123850221 + synonymous_variant Silent SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 74 14 122 1 ENST00000274008.4:c.315A>G p.Gly105= p.G105= ENST00000274008 NM_145207.2 105 ggA/ggG 0 +SPATC1 UCSF GRCh37 8 145086738 145086738 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 16 11 31 0 ENST00000377470.3:c.55C>G p.Arg19Gly p.R19G ENST00000377470 NM_198572.2 19 Cgg/Ggg 0 +SRCRB4D UCSF GRCh37 7 76033635 76033635 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 55 24 56 0 ENST00000275560.3:c.122T>C p.Leu41Pro p.L41P ENST00000275560 NM_080744.1 41 cTc/cCc 0 +SUSD3 UCSF GRCh37 9 95838089 95838089 + missense_variant Missense_Mutation SNP C C A 1000g2011may_all_0.0392 P07_Pri Untested WXS Illumina HiSeq 70 12 43 0 ENST00000375472.3:c.112C>A p.Pro38Thr p.P38T ENST00000375472 NM_145006.2 38 Ccc/Acc 0 +TMEM27 UCSF GRCh37 X 15682877 15682877 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 33 4 58 1 ENST00000380342.3:c.22C>T p.Leu8= p.L8= ENST00000380342 NM_020665.5 8 Ctg/Ttg 0 +TNN UCSF GRCh37 1 175054602 175054602 + synonymous_variant Silent SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 8 7 34 0 ENST00000239462.4:c.1296C>A p.Gly432= p.G432= ENST00000239462 NM_022093.1 432 ggC/ggA 0 +TOR1AIP2 UCSF GRCh37 1 179820453 179820453 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 119 41 122 0 ENST00000367612.3:c.80C>T p.Ala27Val p.A27V ENST00000367612 NM_145034.4 27 gCg/gTg 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 19 87 72 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TPSD1 UCSF GRCh37 16 1307050 1307050 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.019 P07_Pri Untested WXS Illumina HiSeq 27 11 32 1 ENST00000211076.3:c.507C>T p.Asp169= p.D169= ENST00000211076 NM_012217.2 169 gaC/gaT 0 +TPST2 UCSF GRCh37 22 26937357 26937357 + synonymous_variant Silent SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 39 5 30 1 ENST00000338754.4:c.240C>A p.Gly80= p.G80= ENST00000338754 NM_003595.3 80 ggC/ggA 0 +TRIM56 UCSF GRCh37 7 100732823 100732823 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 60 17 59 1 ENST00000306085.6:c.2230A>C p.Thr744Pro p.T744P ENST00000306085 NM_030961.1 744 Acc/Ccc 0 +TTF2 UCSF GRCh37 1 117622249 117622249 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 56 10 88 0 ENST00000369466.4:c.1761G>A p.Gln587= p.Q587= ENST00000369466 NM_003594.3 587 caG/caA 0 +TUBB6 UCSF GRCh37 18 12325728 12325728 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 82 69 105 0 ENST00000317702.5:c.940G>C p.Ala314Pro p.A314P ENST00000317702 314 Gcc/Ccc 0 +UNC13D UCSF GRCh37 17 73832988 73832988 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 43 11 67 1 ENST00000207549.4:c.1067C>G p.Ala356Gly p.A356G ENST00000207549 NM_199242.2 356 gCc/gGc 0 +UPK3BL UCSF GRCh37 7 102279621 102279621 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.034,1000g2011may_all_0.1195,snp132_rs56365279 P07_Pri Untested WXS Illumina HiSeq 14 3 10 0 ENST00000340457.8:c.511G>A p.Glu171Lys p.E171K ENST00000340457 NM_001114403.2 171 Gaa/Aaa 0 +VAX1 UCSF GRCh37 10 118893633 118893633 + synonymous_variant Silent SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 16 9 20 0 ENST00000369206.5:c.891T>G p.Gly297= p.G297= ENST00000369206 NM_001112704.1 297 ggT/ggG 0 +VGF UCSF GRCh37 7 100806737 100806737 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 16 9 22 0 ENST00000249330.2:c.1388A>C p.His463Pro p.H463P ENST00000249330 NM_003378.3 463 cAc/cCc 0 +WDR3 UCSF GRCh37 1 118502003 118502003 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 77 11 63 0 ENST00000349139.5:c.2765C>T p.Thr922Ile p.T922I ENST00000349139 NM_006784.2 922 aCt/aTt 0 +WHAMM UCSF GRCh37 15 83478599 83478599 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 17 9 9 0 ENST00000286760.4:c.121T>C p.Phe41Leu p.F41L ENST00000286760 NM_001080435.1 41 Ttc/Ctc 0 +YEATS2 UCSF GRCh37 3 183515780 183515780 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 128 22 96 0 ENST00000305135.5:c.3167A>G p.Lys1056Arg p.K1056R ENST00000305135 NM_018023.4 1056 aAa/aGa 0 +ZNF513 UCSF GRCh37 2 27601003 27601003 + synonymous_variant Silent SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 62 10 76 0 ENST00000323703.6:c.1035A>G p.Gly345= p.G345= ENST00000323703 NM_144631.5 345 ggA/ggG 0 +ZNF783 UCSF GRCh37 7 148978725 148978725 + intron_variant,NMD_transcript_variant Intron SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 44 9 38 0 ENST00000378052.1:c.802+3107G>C *268* ENST00000378052 0 +ABCB9 UCSF GRCh37 12 123434996 123434996 + splice_donor_variant Splice_Site SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 24 4 26 0 ENST00000280560.8:c.716+2T>G p.X239_splice ENST00000280560 NM_019625.3 0 +ABCG8 UCSF GRCh37 2 44101016 44101016 + synonymous_variant Silent SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 228 26 208 0 ENST00000272286.2:c.1302C>G p.Leu434= p.L434= ENST00000272286 NM_022437.2 434 ctC/ctG 0 +ADAMTS8 UCSF GRCh37 11 130276014 130276014 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 65 8 63 0 ENST00000257359.6:c.2109C>A p.Tyr703Ter p.Y703* ENST00000257359 NM_007037.4 703 taC/taA 0 +AGAP1 UCSF GRCh37 2 237028849 237028849 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 28 29 49 0 ENST00000304032.8:c.2128C>T p.Arg710Trp p.R710W ENST00000304032 NM_001037131.2 710 Cgg/Tgg 0 +ALDH4A1 UCSF GRCh37 1 19202933 19202933 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 18 11 48 0 ENST00000290597.5:c.1214A>G p.Glu405Gly p.E405G ENST00000290597 NM_170726.2 405 gAg/gGg 0 +ANK3 UCSF GRCh37 10 62021707 62021707 + synonymous_variant Silent SNP G G A snp132_rs79510328 P07_Rec Untested WXS Illumina HiSeq 47 8 62 0 ENST00000280772.2:c.708C>T p.Phe236= p.F236= ENST00000280772 NM_020987.3 236 ttC/ttT 0 +ANKRD33 UCSF GRCh37 12 52284892 52284892 + intron_variant Intron SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 93 12 67 0 ENST00000340970.4:c.665-78C>A *222* ENST00000340970 0 +ARNT UCSF GRCh37 1 150801579 150801579 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 90 12 113 0 ENST00000358595.5:c.1157A>C p.Tyr386Ser p.Y386S ENST00000358595 NM_178427.2 386 tAc/tCc 0 +ASH1L UCSF GRCh37 1 155490985 155490985 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 209 30 152 0 ENST00000368346.3:c.326G>C p.Arg109Pro p.R109P ENST00000368346 109 cGa/cCa 0 +ASPM UCSF GRCh37 1 197097791 197097791 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 70 21 100 0 ENST00000367409.4:c.2765G>A p.Ser922Asn p.S922N ENST00000367409 NM_018136.4 922 aGt/aAt 0 +ATAD3A UCSF GRCh37 1 1451415 1451415 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 37 19 64 0 ENST00000378755.5:c.229C>G p.Leu77Val p.L77V ENST00000378755 NM_018188.3 77 Ctg/Gtg 0 +ATF7 UCSF GRCh37 12 53925539 53925539 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 54 11 99 1 ENST00000548446.2:c.949G>C p.Ala317Pro p.A317P ENST00000548446 317 Gcc/Ccc 0 +ATP11A UCSF GRCh37 13 113485856 113485856 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 48 31 42 0 ENST00000375645.3:c.1389C>T p.Asn463= p.N463= ENST00000375645 NM_015205.2 463 aaC/aaT 0 +ATP12A UCSF GRCh37 13 25283587 25283587 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 24 13 51 1 ENST00000381946.3:c.2579T>G p.Val860Gly p.V860G ENST00000381946 860 gTg/gGg 0 +ATRX UCSF GRCh37 X 76912145 76912145 + splice_acceptor_variant Splice_Site SNP T T C NOVEL P07_Rec somatic WXS Sanger Illumina HiSeq 19 41 56 0 ENST00000373344.5:c.4121-2A>G p.X1374_splice ENST00000373344 NM_000489.3 0 +BACE2 UCSF GRCh37 21 42609457 42609457 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 97 25 112 0 ENST00000330333.6:c.419C>G p.Ser140Cys p.S140C ENST00000330333 NM_012105.4 140 tCc/tGc 0 +BIN2 UCSF GRCh37 12 51685455 51685455 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 79 21 72 0 ENST00000267012.4:c.1435C>T p.Pro479Ser p.P479S ENST00000267012 NM_016293.2 479 Cct/Tct 0 +BIN2 UCSF GRCh37 12 51690936 51690936 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 57 7 53 0 ENST00000267012.4:c.615C>G p.Cys205Trp p.C205W ENST00000267012 NM_016293.2 205 tgC/tgG 0 +BPTF UCSF GRCh37 17 65941584 65941584 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 73 9 66 1 ENST00000321892.4:c.7138A>C p.Thr2380Pro p.T2380P ENST00000321892 2380 Acc/Ccc 0 +C15orf17 UCSF GRCh37 15 75194971 75194971 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 84 10 103 0 ENST00000357635.5:c.586A>C p.Thr196Pro p.T196P ENST00000357635 NM_020447.3 196 Acc/Ccc 0 +C17orf46 UCSF GRCh37 17 43332527 43332527 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 44 7 52 2 ENST00000331780.4:c.1022T>C p.Leu341Pro p.L341P ENST00000331780 NM_152343.2 341 cTc/cCc 0 +C17orf46 UCSF GRCh37 17 43332520 43332520 + synonymous_variant Silent SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 66 11 50 1 ENST00000331780.4:c.1029A>C p.Pro343= p.P343= ENST00000331780 NM_152343.2 343 ccA/ccC 0 +C2orf54 UCSF GRCh37 2 241831112 241831112 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 24 6 51 0 ENST00000388934.4:c.583A>G p.Arg195Gly p.R195G ENST00000388934 NM_001085437.1 195 Aga/Gga 0 +C2orf65 UCSF GRCh37 2 74787345 74787345 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec somatic WXS Sanger Illumina HiSeq 33 8 51 0 ENST00000290536.5:c.1355T>G p.Leu452Arg p.L452R ENST00000290536 NM_138804.4 452 cTg/cGg 0 +C5orf55 UCSF GRCh37 5 442884 442884 + synonymous_variant Silent SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 36 8 63 0 ENST00000408966.2:c.54C>G p.Gly18= p.G18= ENST00000408966 NM_138464.2 18 ggC/ggG 0 +C9orf11 UCSF GRCh37 9 27294321 27294321 + synonymous_variant Silent SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 50 34 36 1 ENST00000380032.3:c.282A>G p.Leu94= p.L94= ENST00000380032 NM_020641.2 94 ctA/ctG 0 +CACNA2D4 UCSF GRCh37 12 2017100 2017100 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 27 5 32 0 ENST00000382722.5:c.590A>C p.Asn197Thr p.N197T ENST00000382722 NM_172364.4 197 aAc/aCc 0 +CAND1 UCSF GRCh37 12 67675701 67675701 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 109 23 102 0 ENST00000545606.1:c.80C>A p.Thr27Lys p.T27K ENST00000545606 NM_018448.3 27 aCa/aAa 0 +CARM1 UCSF GRCh37 19 11019790 11019790 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 52 9 52 0 ENST00000327064.4:c.465C>A p.Tyr155Ter p.Y155* ENST00000327064 NM_199141.1 155 taC/taA 0 +CBLL1 UCSF GRCh37 7 107399172 107399174 + inframe_deletion In_Frame_Del DEL CAC CAC - NOVEL P07_Rec Untested WXS Illumina HiSeq 10 0 ENST00000440859.3:c.1029_1031del p.Pro350del p.P350del ENST00000440859 NM_024814.2 342 gCACca/gca 0 +CBLL1 UCSF GRCh37 7 107399173 107399176 + protein_altering_variant In_Frame_Del DEL ACCA ACCA C NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000440859.3:c.1026_1029delinsC p.Pro350del p.P350del ENST00000440859 NM_024814.2 342 gcACCA/gcC 0 +CCDC103 UCSF GRCh37 17 42978399 42978399 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P07_Rec Untested WXS Illumina HiSeq 35 0 ENST00000410006.2:c.35del p.Leu12TrpfsTer45 p.L12Wfs*45 ENST00000410006 NM_001258395.1 11 gcT/gc 0 +CCDC27 UCSF GRCh37 1 3680383 3680383 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 16 8 41 0 ENST00000294600.2:c.1435C>A p.Gln479Lys p.Q479K ENST00000294600 NM_152492.2 479 Caa/Aaa 0 +CDK14 UCSF GRCh37 7 90546941 90546944 + frameshift_variant Frame_Shift_Del DEL GTCT GTCT - NOVEL P07_Rec Untested WXS Illumina HiSeq 31 0 ENST00000380050.3:c.732_735del p.Ser245ThrfsTer12 p.S245Tfs*12 ENST00000380050 NM_001287137.1 243 gGTCTg/gg 0 +CELSR1 UCSF GRCh37 22 46790131 46790131 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 20 11 59 0 ENST00000262738.3:c.5872T>G p.Trp1958Gly p.W1958G ENST00000262738 NM_014246.1 1958 Tgg/Ggg 0 +CHRNA2 UCSF GRCh37 8 27327497 27327497 + splice_region_variant,synonymous_variant Splice_Region SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 32 12 41 1 ENST00000407991.1:c.75T>G p.Gly25= p.G25= ENST00000407991 NM_000742.3 25 ggT/ggG 0 +CLEC7A UCSF GRCh37 12 10279261 10279261 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 93 11 70 0 ENST00000304084.8:c.249C>A p.Tyr83Ter p.Y83* ENST00000304084 NM_197947.2 83 taC/taA 0 +CNTLN UCSF GRCh37 9 17486994 17486995 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P07_Rec Untested WXS Illumina HiSeq 26 0 ENST00000380647.3:c.4054dup p.Thr1352AsnfsTer4 p.T1352Nfs*4 ENST00000380647 1350 gaa/gaAa 0 +COL16A1 UCSF GRCh37 1 32118347 32118370 + frameshift_variant Frame_Shift_Del DEL TGCCTGGCTGGCCCATGGGACCCG TGCCTGGCTGGCCCATGGGACCCG C NOVEL P07_Rec 24 Untested WXS Illumina HiSeq 12 0 ENST00000373672.3:c.4697_4720delinsG p.Pro1566ArgfsTer6 p.P1566Rfs*6 ENST00000373672 NM_001856.3 1566 cCGGGTCCCATGGGCCAGCCAGGCAag/cGag 0 +COL4A4 UCSF GRCh37 2 227875211 227875211 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P07_Rec Untested WXS Illumina HiSeq 9 0 ENST00000396625.3:c.4340del p.Pro1447LeufsTer105 p.P1447Lfs*105 ENST00000396625 NM_000092.4 1447 cCt/ct 0 +CPNE3 UCSF GRCh37 8 87563330 87563330 + splice_donor_variant Splice_Site SNP T T G 1000g2011may_all_0.0465 P07_Rec Untested WXS Illumina HiSeq 38 26 103 1 ENST00000198765.4:c.1068+2T>G p.X356_splice ENST00000198765 0 +CRBN UCSF GRCh37 3 3215909 3215909 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 96 12 117 0 ENST00000231948.4:c.211A>G p.Thr71Ala p.T71A ENST00000231948 NM_016302.3 71 Act/Gct 0 +CSMD2 UCSF GRCh37 1 34554724 34554724 + stop_gained,NMD_transcript_variant Nonsense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 76 10 68 0 ENST00000241312.4:c.138C>A p.Tyr46Ter p.Y46* ENST00000241312 46 taC/taA 0 +CTNNA1 UCSF GRCh37 5 138260372 138260372 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 27 4 37 0 ENST00000302763.7:c.1720G>A p.Glu574Lys p.E574K ENST00000302763 NM_001903.2 574 Gaa/Aaa 0 +CTNNAL1 UCSF GRCh37 9 111718091 111718091 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 105 15 105 0 ENST00000325551.4:c.1608C>A p.Tyr536Ter p.Y536* ENST00000325551 NM_003798.2 536 taC/taA 0 +CYBASC3 UCSF GRCh37 11 61120560 61120560 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 51 8 52 0 ENST00000294072.4:c.445C>G p.Arg149Gly p.R149G ENST00000294072 NM_153611.4 149 Cgc/Ggc 0 +DCHS1 UCSF GRCh37 11 6643472 6643472 + synonymous_variant Silent SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 11 3 29 1 ENST00000299441.3:c.9435T>G p.Gly3145= p.G3145= ENST00000299441 NM_003737.2 3145 ggT/ggG 0 +DDHD2 UCSF GRCh37 8 38111154 38111154 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 175 37 131 0 ENST00000397166.2:c.1972C>T p.Arg658Cys p.R658C ENST00000397166 NM_015214.2 658 Cgc/Tgc 0 +DDX60L UCSF GRCh37 4 169315741 169315741 + stop_gained Nonsense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 173 32 138 0 ENST00000260184.7:c.3685C>T p.Arg1229Ter p.R1229* ENST00000260184 NM_001012967.1 1229 Cga/Tga 0 +DEFB126 UCSF GRCh37 20 126310 126311 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P07_Rec Untested WXS Illumina HiSeq 8 0 ENST00000382398.3:c.313_314del p.Thr105ProfsTer? p.T105Pfs*? ENST00000382398 NM_030931.3 105 ACc/c 0 +DIS3 UCSF GRCh37 13 73337743 73337743 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 74 13 132 1 ENST00000377767.4:c.1973A>G p.Glu658Gly p.E658G ENST00000377767 NM_014953.3 658 gAa/gGa 0 +DIXDC1 UCSF GRCh37 11 111853109 111853109 + frameshift_variant,splice_region_variant Frame_Shift_Ins INS T T CC NOVEL P07_Rec Untested WXS Illumina HiSeq 11 0 ENST00000440460.2:c.813delinsCC p.Gly272ArgfsTer44 p.G272Rfs*44 ENST00000440460 NM_001037954.3 271 ccT/ccCC 0 +DNAJA3 UCSF GRCh37 16 4500462 4500462 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 21 4 14 0 ENST00000262375.6:c.1303G>A p.Glu435Lys p.E435K ENST00000262375 NM_005147.5 435 Gag/Aag 0 +DNMT1 UCSF GRCh37 19 10270707 10270742 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACTGTTTTGGCGCGAGCCATTTTTTTCTCCGTTCTG ACTGTTTTGGCGCGAGCCATTTTTTTCTCCGTTCTG GTTGTTGTGGGGGGAGCCATTTTTTTCTCCGTTCT NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000340748.4:c.996-3_1028delinsAGAACGGAGAAAAAAATGGCTCCCCCCACAACAAC p.X332_splice ENST00000340748 0 +DOK6 UCSF GRCh37 18 67508602 67508602 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 93 12 101 0 ENST00000382713.5:c.979T>C p.Ser327Pro p.S327P ENST00000382713 NM_152721.5 327 Tcc/Ccc 0 +ERBB2IP UCSF GRCh37 5 65374262 65374262 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 74 19 100 0 ENST00000284037.5:c.4143C>A p.Tyr1381Ter p.Y1381* ENST00000284037 NM_001253697.1 1381 taC/taA 0 +ERGIC3 UCSF GRCh37 20 34145203 34145203 + synonymous_variant Silent SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 69 9 89 0 ENST00000348547.2:c.1080A>G p.Gly360= p.G360= ENST00000348547 NM_015966.2 360 ggA/ggG 0 +ETFA UCSF GRCh37 15 76578040 76578040 + missense_variant Missense_Mutation SNP T T A NOVEL P07_Rec Untested WXS Illumina HiSeq 77 31 83 1 ENST00000557943.1:c.602A>T p.Asp201Val p.D201V ENST00000557943 NM_000126.3 201 gAc/gTc 0 +FAM108A1 UCSF GRCh37 19 1881408 1881408 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 60 9 40 0 ENST00000292577.7:c.158T>C p.Leu53Ser p.L53S ENST00000292577 NM_001130111.1 53 tTg/tCg 0 +FAM58BP UCSF GRCh37 1 200183278 200183278 + non_coding_transcript_exon_variant RNA SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0088 P07_Rec Untested WXS Illumina HiSeq 88 17 59 0 ENST00000424019.1:n.623C>T *208* ENST00000424019 0 +FCER1A UCSF GRCh37 1 159275786 159275786 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 72 12 115 0 ENST00000368115.1:c.340C>G p.Leu114Val p.L114V ENST00000368115 NM_002001.3 114 Ctc/Gtc 0 +FMN1 UCSF GRCh37 15 33261341 33261341 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 61 37 70 1 ENST00000559047.1:c.2561T>C p.Leu854Pro p.L854P ENST00000559047 NM_001277313.1 854 cTc/cCc 0 +GFM1 UCSF GRCh37 3 158384100 158384100 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 41 12 32 0 ENST00000486715.1:c.1526A>G p.Glu509Gly p.E509G ENST00000486715 NM_024996.5 509 gAa/gGa 0 +GGTLC2 UCSF GRCh37 22 22988917 22988917 + synonymous_variant Silent SNP T T C 1000g2011may_all_0.0094,snp132_rs71316772 P07_Rec Untested WXS Illumina HiSeq 22 5 16 0 ENST00000480559.1:c.102T>C p.Asp34= p.D34= ENST00000480559 NM_199127.2 34 gaT/gaC 0 +GIF UCSF GRCh37 11 59610508 59610508 + synonymous_variant Silent SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 56 13 67 1 ENST00000257248.2:c.363A>C p.Ala121= p.A121= ENST00000257248 NM_005142.2 121 gcA/gcC 0 +GIGYF1 UCSF GRCh37 7 100285167 100285167 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec somatic WXS Sanger Illumina HiSeq 68 13 72 0 ENST00000275732.5:c.334G>C p.Ala112Pro p.A112P ENST00000275732 NM_022574.4 112 Gct/Cct 0 +GOLGB1 UCSF GRCh37 3 121435721 121435721 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 204 37 166 0 ENST00000340645.5:c.1136C>G p.Ser379Cys p.S379C ENST00000340645 NM_001256487.1 379 tCt/tGt 0 +GORASP2 UCSF GRCh37 2 171806771 171806771 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 70 17 58 0 ENST00000234160.4:c.406A>G p.Ile136Val p.I136V ENST00000234160 NM_015530.4 136 Ata/Gta 0 +GPR26 UCSF GRCh37 10 125447449 125447449 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 45 16 76 0 ENST00000284674.1:c.787G>A p.Val263Met p.V263M ENST00000284674 NM_153442.3 263 Gtg/Atg 0 +GRXCR1 UCSF GRCh37 4 43032401 43032401 + synonymous_variant Silent SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 118 53 120 0 ENST00000399770.2:c.717T>C p.Cys239= p.C239= ENST00000399770 NM_001080476.2 239 tgT/tgC 0 +HDLBP UCSF GRCh37 2 242179463 242179463 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P07_Rec Untested WXS Illumina HiSeq 13 0 ENST00000391975.1:c.2244del p.Ile750PhefsTer24 p.I750Ffs*24 ENST00000391975 NM_203346.3 748 ggC/gg 0 +HEATR2 UCSF GRCh37 7 796564 796564 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 21 14 42 0 ENST00000297440.6:c.1403T>C p.Leu468Pro p.L468P ENST00000297440 NM_017802.3 468 cTc/cCc 0 +HLA-DQB1 UCSF GRCh37 6 32629150 32629150 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 21 47 49 0 ENST00000374943.4:c.746T>C p.Leu249Pro p.L249P ENST00000374943 NM_001243961.1 249 cTt/cCt 0 +HLX UCSF GRCh37 1 221054610 221054610 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 129 23 98 0 ENST00000366903.6:c.667T>C p.Phe223Leu p.F223L ENST00000366903 NM_021958.3 223 Ttc/Ctc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 83 51 98 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +ILK UCSF GRCh37 11 6629291 6629291 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 78 13 94 0 ENST00000299421.4:c.105C>T p.Phe35= p.F35= ENST00000299421 NM_004517.3 35 ttC/ttT 0 +IPO5 UCSF GRCh37 13 98637679 98637679 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 110 16 118 0 ENST00000357602.3:c.176G>A p.Arg59Lys p.R59K ENST00000357602 59 aGa/aAa 0 +IRX6 UCSF GRCh37 16 55361522 55361522 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 34 28 70 0 ENST00000290552.7:c.438C>T p.Gly146= p.G146= ENST00000290552 NM_024335.2 146 ggC/ggT 0 +KIAA0564 UCSF GRCh37 13 42164786 42164786 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 105 12 61 0 ENST00000379310.3:c.5102T>G p.Leu1701Arg p.L1701R ENST00000379310 NM_015058.1 1701 cTg/cGg 0 +KIAA1267 UCSF GRCh37 17 44144000 44144002 + inframe_deletion In_Frame_Del DEL GAT GAT - NOVEL P07_Rec Untested WXS Illumina HiSeq 30 0 ENST00000574590.1:c.1749_1751del p.Ser584del p.S584del ENST00000574590 NM_001193465.1 583 tcATCt/tct 0 +KIAA1462 UCSF GRCh37 10 30316881 30316881 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 75 56 69 0 ENST00000375377.1:c.2196G>A p.Thr732= p.T732= ENST00000375377 NM_020848.2 732 acG/acA 0 +KRBA1 UCSF GRCh37 7 149430470 149430470 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 98 42 68 0 ENST00000319551.8:c.2244C>T p.Ala748= p.A748= ENST00000319551 748 gcC/gcT 0 +KRT7 UCSF GRCh37 12 52642412 52642412 + synonymous_variant Silent SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 24 4 44 0 ENST00000331817.5:c.1278T>G p.Gly426= p.G426= ENST00000331817 NM_005556.3 426 ggT/ggG 0 +L3MBTL3 UCSF GRCh37 6 130387509 130387509 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 95 12 129 0 ENST00000361794.2:c.876C>A p.Tyr292Ter p.Y292* ENST00000361794 NM_032438.2 292 taC/taA 0 +LAMA2 UCSF GRCh37 6 129824352 129824352 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 96 64 106 0 ENST00000421865.2:c.8474T>C p.Phe2825Ser p.F2825S ENST00000421865 NM_001079823.1 2825 tTc/tCc 0 +LAMB4 UCSF GRCh37 7 107703235 107703235 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 67 10 64 0 ENST00000205386.4:c.3266G>T p.Ser1089Ile p.S1089I ENST00000205386 1089 aGt/aTt 0 +LANCL3 UCSF GRCh37 X 37518731 37518731 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 27 5 35 0 ENST00000378619.3:c.714G>T p.Leu238Phe p.L238F ENST00000378619 NM_001170331.1 238 ttG/ttT 0 +LRP2 UCSF GRCh37 2 169993907 169993907 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 91 54 95 0 ENST00000263816.3:c.13615A>G p.Ile4539Val p.I4539V ENST00000263816 NM_004525.2 4539 Atc/Gtc 0 +MAK16 UCSF GRCh37 8 33346526 33346526 + stop_gained Nonsense_Mutation SNP T T A NOVEL P07_Rec Untested WXS Illumina HiSeq 196 37 158 0 ENST00000360128.6:c.261T>A p.Tyr87Ter p.Y87* ENST00000360128 NM_032509.3 87 taT/taA 0 +MAPK8IP3 UCSF GRCh37 16 1815990 1815990 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 15 16 36 0 ENST00000250894.4:c.2473G>A p.Glu825Lys p.E825K ENST00000250894 NM_015133.3 825 Gag/Aag 0 +MEF2C UCSF GRCh37 5 88025121 88025121 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 109 13 64 0 ENST00000437473.2:c.878C>A p.Thr293Asn p.T293N ENST00000437473 NM_001193350.1 293 aCc/aAc 0 +MLL3 UCSF GRCh37 7 151874148 151874149 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000262189.6:c.8390dup p.Glu2798GlyfsTer11 p.E2798Gfs*11 ENST00000262189 NM_170606.2 2797 aag/aAag 0 +MPP4 UCSF GRCh37 2 202545740 202545740 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 151 18 117 0 ENST00000409474.3:c.750G>A p.Met250Ile p.M250I ENST00000409474 NM_033066.2 250 atG/atA 0 +MRPL47 UCSF GRCh37 3 179310526 179310526 + missense_variant,splice_region_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 52 16 100 0 ENST00000476781.1:c.535C>G p.His179Asp p.H179D ENST00000476781 NM_020409.2 179 Cac/Gac 0 +MTHFR UCSF GRCh37 1 11854002 11854002 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 56 12 55 0 ENST00000376590.3:c.1492G>A p.Val498Met p.V498M ENST00000376590 NM_005957.4 498 Gtg/Atg 0 +NARS2 UCSF GRCh37 11 78277317 78277317 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 90 23 135 2 ENST00000281038.5:c.374A>G p.Asp125Gly p.D125G ENST00000281038 NM_001243251.1 125 gAt/gGt 0 +NLGN4Y UCSF GRCh37 Y 16942197 16942197 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 39 9 74 0 ENST00000339174.5:c.1399A>C p.Thr467Pro p.T467P ENST00000339174 467 Acc/Ccc 0 +NLRP3 UCSF GRCh37 1 247587244 247587244 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 52 7 55 0 ENST00000336119.3:c.499C>T p.Arg167Cys p.R167C ENST00000336119 NM_001127462.2 167 Cgc/Tgc 0 +NOTCH1 UCSF GRCh37 9 139391036 139391036 + synonymous_variant Silent SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 43 8 76 0 ENST00000277541.6:c.7155G>C p.Val2385= p.V2385= ENST00000277541 NM_017617.3 2385 gtG/gtC 0 +NUDT10 UCSF GRCh37 X 51076024 51076024 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.00397,1000g2011may_all_0.0126,snp132_rs2801626 P07_Rec Untested WXS Illumina HiSeq 53 6 33 0 ENST00000356450.2:c.207G>A p.Glu69= p.E69= ENST00000356450 69 gaG/gaA 0 +OCA2 UCSF GRCh37 15 28231781 28231781 + missense_variant Missense_Mutation SNP T T A NOVEL P07_Rec Untested WXS Illumina HiSeq 146 18 160 0 ENST00000354638.3:c.1191A>T p.Leu397Phe p.L397F ENST00000354638 NM_000275.2 397 ttA/ttT 0 +OR4A15 UCSF GRCh37 11 55135516 55135516 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 212 26 196 0 ENST00000314706.3:c.157A>G p.Lys53Glu p.K53E ENST00000314706 NM_001005275.1 53 Aag/Gag 0 +PCDHB14 UCSF GRCh37 5 140604999 140604999 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 36 11 50 0 ENST00000239449.4:c.1922T>G p.Val641Gly p.V641G ENST00000239449 NM_018934.2 641 gTg/gGg 0 +PCNX UCSF GRCh37 14 71568927 71568927 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P07_Rec Untested WXS Illumina HiSeq 17 0 ENST00000304743.2:c.5812del p.Val1938SerfsTer4 p.V1938Sfs*4 ENST00000304743 NM_014982.2 1937 aGg/ag 0 +PCNXL3 UCSF GRCh37 11 65402768 65402768 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 10 4 16 1 ENST00000355703.3:c.5033T>G p.Val1678Gly p.V1678G ENST00000355703 NM_032223.2 1678 gTc/gGc 0 +PGC UCSF GRCh37 6 41715059 41715059 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 41 7 61 1 ENST00000373025.3:c.14T>G p.Val5Gly p.V5G ENST00000373025 NM_002630.3 5 gTg/gGg 0 +PNLIP UCSF GRCh37 10 118307928 118307928 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 199 30 154 0 ENST00000369221.2:c.258A>C p.Lys86Asn p.K86N ENST00000369221 NM_000936.2 86 aaA/aaC 0 +PNOC UCSF GRCh37 8 28196684 28196684 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 34 10 77 0 ENST00000301908.3:c.254A>C p.Tyr85Ser p.Y85S ENST00000301908 NM_006228.3 85 tAc/tCc 0 +PRKG1 UCSF GRCh37 10 53564389 53564389 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 82 12 97 0 ENST00000373985.1:c.556C>G p.Gln186Glu p.Q186E ENST00000373985 NM_001098512.2 186 Caa/Gaa 0 +PRSS1 UCSF GRCh37 7 142460412 142460431 + coding_sequence_variant,intron_variant In_Frame_Del DEL ATGTCAGGTGATTTGACCAA ATGTCAGGTGATTTGACCAA CTGCCAGGTGATTTGAC NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000311737.7:c.585_591+13delinsCTGCCAGGTGATTTGAC *195* ENST00000311737 NM_002769.4 195 0 +PRSS48 UCSF GRCh37 4 152201017 152201018 + frameshift_variant Frame_Shift_Ins INS - - GGCAG NOVEL P07_Rec Untested WXS Illumina HiSeq 9 0 ENST00000455694.2:c.123_124insGCAGG p.Gln42AlafsTer23 p.Q42Afs*23 ENST00000455694 NM_183375.2 41 tgg/tgGGCAGg 0 +PSMD10 UCSF GRCh37 X 107331324 107331324 + synonymous_variant Silent SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 35 11 63 0 ENST00000217958.3:c.219T>G p.Gly73= p.G73= ENST00000217958 NM_170750.2 73 ggT/ggG 0 +RNF133 UCSF GRCh37 7 122338115 122338115 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 289 35 165 0 ENST00000340112.2:c.858G>C p.Trp286Cys p.W286C ENST00000340112 NM_139175.1 286 tgG/tgC 0 +SDF2 UCSF GRCh37 17 26982450 26982450 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P07_Rec Untested WXS Illumina HiSeq 21 0 ENST00000247020.4:c.203del p.Ser68IlefsTer27 p.S68Ifs*27 ENST00000247020 NM_006923.3 68 aGt/at 0 +SEMA3G UCSF GRCh37 3 52474094 52474094 + synonymous_variant Silent SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 52 8 42 0 ENST00000231721.2:c.1164A>G p.Ala388= p.A388= ENST00000231721 NM_020163.1 388 gcA/gcG 0 +SGIP1 UCSF GRCh37 1 67147609 67147609 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 179 34 136 0 ENST00000371037.4:c.872T>C p.Leu291Ser p.L291S ENST00000371037 NM_032291.2 291 tTg/tCg 0 +SIGLEC12 UCSF GRCh37 19 52001516 52001516 + synonymous_variant Silent SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 52 10 82 1 ENST00000291707.3:c.1161G>C p.Ser387= p.S387= ENST00000291707 NM_053003.2 387 tcG/tcC 0 +SLC15A3 UCSF GRCh37 11 60714292 60714292 + missense_variant,splice_region_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 54 9 74 0 ENST00000227880.3:c.560T>G p.Val187Gly p.V187G ENST00000227880 NM_016582.2 187 gTg/gGg 0 +SLC1A5 UCSF GRCh37 19 47281995 47281995 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 45 14 46 0 ENST00000542575.2:c.995A>C p.Asn332Thr p.N332T ENST00000542575 NM_005628.2 332 aAc/aCc 0 +SLC22A15 UCSF GRCh37 1 116562262 116562262 + synonymous_variant Silent SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 252 35 192 0 ENST00000369503.4:c.360T>C p.Ser120= p.S120= ENST00000369503 NM_018420.2 120 agT/agC 0 +SLC24A1 UCSF GRCh37 15 65918177 65918179 + inframe_deletion In_Frame_Del DEL CTG CTG - 1000g2010nov_all P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000261892.6:c.1771_1773delCTG p.Leu591del p.L591del ENST00000261892 NM_004727.2 587 CTG/- 0 +SLC25A11 UCSF GRCh37 17 4841768 4841805 + splice_donor_variant,intron_variant Splice_Site INS AGACCTCACAGCCCCCAAGTCTCCAGCCCCTCCACTCA AGACCTCACAGCCCCCAAGTCTCCAGCCCCTCCACTCA CACCCCCCCCCCCCCCAACCCCCCCAGCCCCTCCCCCCC NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000225665.7:c.546+2_546+39delinsGGGGGGGAGGGGCTGGGGGGGTTGGGGGGGGGGGGGGTG p.X182_splice ENST00000225665 NM_001165417.1 0 +SLC39A10 UCSF GRCh37 2 196544942 196544942 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000359634.5:c.183del p.Lys61AsnfsTer26 p.K61Nfs*26 ENST00000359634 NM_020342.2 59 gAa/ga 0 +SLC3A1 UCSF GRCh37 2 44539860 44539860 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 83 15 77 0 ENST00000260649.6:c.1468G>T p.Val490Leu p.V490L ENST00000260649 NM_000341.3 490 Gta/Tta 0 +SLC41A1 UCSF GRCh37 1 205760812 205760812 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 42 8 57 0 ENST00000367137.3:c.1391T>G p.Val464Gly p.V464G ENST00000367137 NM_173854.4 464 gTg/gGg 0 +SLC4A9 UCSF GRCh37 5 139743677 139743677 + synonymous_variant Silent SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 34 8 51 2 ENST00000507527.1:c.1365A>G p.Gly455= p.G455= ENST00000507527 455 ggA/ggG 0 +SLC5A10 UCSF GRCh37 17 18923739 18923739 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 38 25 65 2 ENST00000395645.3:c.1786G>C p.Ala596Pro p.A596P ENST00000395645 NM_001042450.2 596 Gcc/Ccc 0 +SLC5A8 UCSF GRCh37 12 101588918 101588918 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0014 P07_Rec Untested WXS Illumina HiSeq 84 12 60 0 ENST00000536262.2:c.492C>T p.Gly164= p.G164= ENST00000536262 NM_145913.3 164 ggC/ggT 0 +SLC7A4 UCSF GRCh37 22 21384142 21384142 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 32 27 54 0 ENST00000382932.2:c.1481G>T p.Cys494Phe p.C494F ENST00000382932 NM_004173.2 494 tGc/tTc 0 +SMARCA4 UCSF GRCh37 19 11096909 11096909 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec somatic WXS Sanger Illumina HiSeq 59 10 61 0 ENST00000344626.4:c.400G>C p.Val134Leu p.V134L ENST00000344626 NM_003072.3 134 Gtt/Ctt 0 +SPATC1 UCSF GRCh37 8 145086738 145086738 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 13 12 31 0 ENST00000377470.3:c.55C>G p.Arg19Gly p.R19G ENST00000377470 NM_198572.2 19 Cgg/Ggg 0 +SRCRB4D UCSF GRCh37 7 76033635 76033635 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 27 16 56 0 ENST00000275560.3:c.122T>C p.Leu41Pro p.L41P ENST00000275560 NM_080744.1 41 cTc/cCc 0 +STOML2 UCSF GRCh37 9 35102804 35102804 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 53 8 75 0 ENST00000356493.5:c.62C>T p.Ser21Phe p.S21F ENST00000356493 NM_013442.1 21 tCt/tTt 0 +SUSD2 UCSF GRCh37 22 24583952 24583952 + synonymous_variant Silent SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 35 8 40 0 ENST00000358321.3:c.2190A>C p.Pro730= p.P730= ENST00000358321 NM_019601.3 730 ccA/ccC 0 +SUSD3 UCSF GRCh37 9 95838089 95838089 + missense_variant Missense_Mutation SNP C C A 1000g2011may_all_0.0392 P07_Rec Untested WXS Illumina HiSeq 51 11 43 0 ENST00000375472.3:c.112C>A p.Pro38Thr p.P38T ENST00000375472 NM_145006.2 38 Ccc/Acc 0 +T UCSF GRCh37 6 166576023 166576023 + synonymous_variant Silent SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 52 12 50 0 ENST00000296946.2:c.816C>T p.Ser272= p.S272= ENST00000296946 NM_003181.3 272 tcC/tcT 0 +TCEB3C UCSF GRCh37 18 44554967 44554967 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 109 13 307 0 ENST00000330682.2:c.1247A>C p.Tyr416Ser p.Y416S ENST00000330682 NM_145653.3 416 tAc/tCc 0 +TCERG1L UCSF GRCh37 10 132915117 132915117 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 54 10 84 0 ENST00000368642.4:c.1340T>C p.Leu447Pro p.L447P ENST00000368642 NM_174937.3 447 cTc/cCc 0 +TMEM144 UCSF GRCh37 4 159158783 159158783 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 58 14 88 0 ENST00000296529.6:c.670G>A p.Ala224Thr p.A224T ENST00000296529 NM_018342.4 224 Gca/Aca 0 +TMEM155 UCSF GRCh37 4 122681471 122681471 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 59 7 85 0 ENST00000337677.5:c.371C>A p.Thr124Asn p.T124N ENST00000337677 NM_152399.2 124 aCt/aAt 0 +TMEM161A UCSF GRCh37 19 19232150 19232150 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 24 9 48 1 ENST00000162044.9:c.881A>C p.His294Pro p.H294P ENST00000162044 NM_017814.2 294 cAc/cCc 0 +TMEM175 UCSF GRCh37 4 949253 949253 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 35 4 35 0 ENST00000264771.4:c.688T>G p.Cys230Gly p.C230G ENST00000264771 NM_032326.2 230 Tgc/Ggc 0 +TMEM177 UCSF GRCh37 2 120438443 120438443 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 36 6 81 0 ENST00000272521.6:c.14T>C p.Leu5Pro p.L5P ENST00000272521 NM_030577.2 5 cTg/cCg 0 +TMPRSS9 UCSF GRCh37 19 2422016 2422016 + synonymous_variant Silent SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 120 14 109 0 ENST00000332578.3:c.2217C>A p.Pro739= p.P739= ENST00000332578 NM_182973.1 739 ccC/ccA 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 17 80 72 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TPSD1 UCSF GRCh37 16 1307050 1307050 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.019 P07_Rec Untested WXS Illumina HiSeq 34 5 32 1 ENST00000211076.3:c.507C>T p.Asp169= p.D169= ENST00000211076 NM_012217.2 169 gaC/gaT 0 +TPX2 UCSF GRCh37 20 30385297 30385297 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 134 59 157 0 ENST00000300403.6:c.1924A>G p.Lys642Glu p.K642E ENST00000300403 NM_012112.4 642 Aaa/Gaa 0 +TRIM56 UCSF GRCh37 7 100732823 100732823 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 59 14 59 1 ENST00000306085.6:c.2230A>C p.Thr744Pro p.T744P ENST00000306085 NM_030961.1 744 Acc/Ccc 0 +TUBB6 UCSF GRCh37 18 12325728 12325728 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 87 57 105 0 ENST00000317702.5:c.940G>C p.Ala314Pro p.A314P ENST00000317702 314 Gcc/Ccc 0 +TUBG2 UCSF GRCh37 17 40815072 40815072 + splice_donor_variant Splice_Site SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 63 14 89 0 ENST00000251412.7:c.479+2C>A p.X160_splice ENST00000251412 NM_016437.2 0 +UGT1A3 UCSF GRCh37 2 234638624 234638624 + synonymous_variant Silent SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 81 10 165 0 ENST00000482026.1:c.852G>A p.Arg284= p.R284= ENST00000482026 284 agG/agA 0 +UPK3BL UCSF GRCh37 7 102279621 102279621 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.034,1000g2011may_all_0.1195,snp132_rs56365279 P07_Rec Untested WXS Illumina HiSeq 10 5 10 0 ENST00000340457.8:c.511G>A p.Glu171Lys p.E171K ENST00000340457 NM_001114403.2 171 Gaa/Aaa 0 +USP21 UCSF GRCh37 1 161132755 161132755 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 115 13 95 0 ENST00000289865.8:c.940C>A p.His314Asn p.H314N ENST00000289865 NM_012475.4 314 Cac/Aac 0 +VAX1 UCSF GRCh37 10 118893633 118893633 + synonymous_variant Silent SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 10 4 20 0 ENST00000369206.5:c.891T>G p.Gly297= p.G297= ENST00000369206 NM_001112704.1 297 ggT/ggG 0 +VGF UCSF GRCh37 7 100806737 100806737 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 24 9 22 0 ENST00000249330.2:c.1388A>C p.His463Pro p.H463P ENST00000249330 NM_003378.3 463 cAc/cCc 0 +ZCCHC16 UCSF GRCh37 X 111698509 111698513 + frameshift_variant Frame_Shift_Del DEL GAAAA GAAAA - NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000340433.2:c.554_558del p.Glu185GlyfsTer4 p.E185Gfs*4 ENST00000340433 NM_001004308.2 185 GAAAAg/g 0 +ZNRF3 UCSF GRCh37 22 29445795 29445795 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 30 7 56 0 ENST00000544604.2:c.1626C>A p.Tyr542Ter p.Y542* ENST00000544604 NM_001206998.1 542 taC/taA 0 +ACR UCSF GRCh37 22 51178337 51178337 + missense_variant Missense_Mutation SNP T T G NOVEL P08_Pri Untested WXS Illumina HiSeq 48 34 91 0 ENST00000216139.5:c.497T>G p.Phe166Cys p.F166C ENST00000216139 NM_001097.2 166 tTt/tGt 0 +ATR UCSF GRCh37 3 142176497 142176497 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P08_Pri Untested WXS Illumina HiSeq 25 0 ENST00000350721.4:c.7604del p.Ala2535AspfsTer6 p.A2535Dfs*6 ENST00000350721 NM_001184.3 2535 gCa/ga 0 +ATRX UCSF GRCh37 X 76938089 76938090 + frameshift_variant Frame_Shift_Del DEL TC TC - NOVEL P08_Pri Untested WXS Illumina HiSeq 26 0 ENST00000373344.5:c.2658_2659del p.Glu886AspfsTer10 p.E886Dfs*10 ENST00000373344 NM_000489.3 886 gaGAct/gact 0 +BMP10 UCSF GRCh37 2 69092971 69092971 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 62 13 141 0 ENST00000295379.1:c.1067G>A p.Cys356Tyr p.C356Y ENST00000295379 NM_014482.1 356 tGt/tAt 0 +CCDC91 UCSF GRCh37 12 28603099 28603099 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Pri Untested WXS Illumina HiSeq 74 15 153 0 ENST00000381259.1:c.768G>T p.Gln256His p.Q256H ENST00000381259 NM_018318.3 256 caG/caT 0 +CNOT6 UCSF GRCh37 5 179977041 179977041 + missense_variant Missense_Mutation SNP A A C NOVEL P08_Pri Untested WXS Illumina HiSeq 61 7 152 0 ENST00000261951.4:c.223A>C p.Asn75His p.N75H ENST00000261951 NM_015455.3 75 Aat/Cat 0 +COG4 UCSF GRCh37 16 70551568 70551568 + synonymous_variant Silent SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 58 8 131 0 ENST00000323786.5:c.330G>A p.Glu110= p.E110= ENST00000323786 NM_015386.2 110 gaG/gaA 0 +CPNE8 UCSF GRCh37 12 39047732 39047732 + synonymous_variant Silent SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 43 23 95 0 ENST00000331366.5:c.1647G>A p.Ala549= p.A549= ENST00000331366 NM_153634.2 549 gcG/gcA 0 +DDX60 UCSF GRCh37 4 169194524 169194524 + missense_variant Missense_Mutation SNP G G C NOVEL P08_Pri Untested WXS Illumina HiSeq 61 12 173 0 ENST00000393743.3:c.2480C>G p.Thr827Ser p.T827S ENST00000393743 NM_017631.5 827 aCt/aGt 0 +FANCF UCSF GRCh37 11 22646911 22646911 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Pri Untested WXS Illumina HiSeq 42 19 170 0 ENST00000327470.3:c.446A>G p.Asn149Ser p.N149S ENST00000327470 NM_022725.3 149 aAt/aGt 0 +GGT7 UCSF GRCh37 20 33440238 33440238 + stop_gained Nonsense_Mutation SNP G G A NOVEL P08_Pri Untested WXS Illumina HiSeq 34 15 92 0 ENST00000336431.5:c.1423C>T p.Gln475Ter p.Q475* ENST00000336431 NM_178026.2 475 Cag/Tag 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 65 20 143 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +MSTN UCSF GRCh37 2 190925003 190925003 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Pri Untested WXS Illumina HiSeq 77 38 204 0 ENST00000260950.4:c.532A>G p.Lys178Glu p.K178E ENST00000260950 NM_005259.2 178 Aaa/Gaa 0 +MYF5 UCSF GRCh37 12 81110945 81110945 + stop_gained Nonsense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 21 6 46 0 ENST00000228644.3:c.103C>T p.Arg35Ter p.R35* ENST00000228644 NM_005593.2 35 Cga/Tga 0 +NBAS UCSF GRCh37 2 15679476 15679476 + synonymous_variant Silent SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 68 15 152 0 ENST00000281513.5:c.384G>A p.Pro128= p.P128= ENST00000281513 NM_015909.3 128 ccG/ccA 0 +PIK3C2B UCSF GRCh37 1 204400818 204400818 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P08_Pri Untested WXS Illumina HiSeq 6 0 ENST00000367187.3:c.4259del p.Phe1420SerfsTer14 p.F1420Sfs*14 ENST00000367187 NM_002646.3 1420 tTc/tc 0 +PRMT5 UCSF GRCh37 14 23396859 23396859 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Pri somatic WXS Sanger Illumina HiSeq 52 20 110 0 ENST00000324366.8:c.326A>G p.Gln109Arg p.Q109R ENST00000324366 NM_006109.3 109 cAg/cGg 0 +RP1 UCSF GRCh37 8 55538949 55538949 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 92 18 144 0 ENST00000220676.1:c.2507C>T p.Pro836Leu p.P836L ENST00000220676 NM_006269.1 836 cCg/cTg 0 +TBCE UCSF GRCh37 1 235600735 235600735 + synonymous_variant Silent SNP G G A NOVEL P08_Pri Untested WXS Illumina HiSeq 34 23 97 0 ENST00000366601.3:c.1062G>A p.Ala354= p.A354= ENST00000366601 354 gcG/gcA 0 +TP53 UCSF GRCh37 17 7577099 7577099 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 10 20 65 0 ENST00000269305.4:c.839G>A p.Arg280Lys p.R280K ENST00000269305 NM_001126112.2 280 aGa/aAa 0 +USH2A UCSF GRCh37 1 215901628 215901628 + missense_variant Missense_Mutation SNP A A G NOVEL P08_Pri Untested WXS Illumina HiSeq 55 19 179 0 ENST00000307340.3:c.11810T>C p.Leu3937Pro p.L3937P ENST00000307340 NM_206933.2 3937 cTc/cCc 0 +USH2A UCSF GRCh37 1 216363700 216363700 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Pri Untested WXS Illumina HiSeq 80 25 185 0 ENST00000307340.3:c.4261A>G p.Thr1421Ala p.T1421A ENST00000307340 NM_206933.2 1421 Act/Gct 0 +WDR63 UCSF GRCh37 1 85583512 85583512 + missense_variant Missense_Mutation SNP C C G NOVEL P08_Pri Untested WXS Illumina HiSeq 64 33 194 0 ENST00000294664.6:c.1887C>G p.Asp629Glu p.D629E ENST00000294664 NM_145172.3 629 gaC/gaG 0 +ZBTB20 UCSF GRCh37 3 114070562 114070564 + inframe_deletion In_Frame_Del DEL CAC CAC - NOVEL P08_Pri Untested WXS Illumina HiSeq 10 0 ENST00000474710.1:c.361_363del p.Val121del p.V121del ENST00000474710 NM_001164342.1 121 GTG/- 0 +ACR UCSF GRCh37 22 51178337 51178337 + missense_variant Missense_Mutation SNP T T G NOVEL P08_Rec Untested WXS Illumina HiSeq 61 46 91 0 ENST00000216139.5:c.497T>G p.Phe166Cys p.F166C ENST00000216139 NM_001097.2 166 tTt/tGt 0 +APOH UCSF GRCh37 17 64210715 64210718 + frameshift_variant Frame_Shift_Del DEL CTCT CTCT - NOVEL P08_Rec Untested WXS Illumina HiSeq 14 0 ENST00000205948.6:c.835_838del p.Arg279Ter p.R279* ENST00000205948 NM_000042.2 279 AGAGta/ta 0 +ATR UCSF GRCh37 3 142176497 142176497 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P08_Rec Untested WXS Illumina HiSeq 48 0 ENST00000350721.4:c.7604del p.Ala2535AspfsTer6 p.A2535Dfs*6 ENST00000350721 NM_001184.3 2535 gCa/ga 0 +ATRX UCSF GRCh37 X 76938089 76938090 + frameshift_variant Frame_Shift_Del DEL TC TC - NOVEL P08_Rec Untested WXS Illumina HiSeq 72 0 ENST00000373344.5:c.2658_2659del p.Glu886AspfsTer10 p.E886Dfs*10 ENST00000373344 NM_000489.3 886 gaGAct/gact 0 +CARM1 UCSF GRCh37 19 11024651 11024651 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 26 21 46 0 ENST00000327064.4:c.768G>A p.Ser256= p.S256= ENST00000327064 NM_199141.1 256 tcG/tcA 0 +CASP5 UCSF GRCh37 11 104869682 104869682 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 71 50 149 0 ENST00000260315.3:c.1026C>T p.Asn342= p.N342= ENST00000260315 342 aaC/aaT 0 +CENPQ UCSF GRCh37 6 49438702 49438702 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P08_Rec Untested WXS Illumina HiSeq 6 0 ENST00000335783.3:c.125del p.Asn42IlefsTer5 p.N42Ifs*5 ENST00000335783 NM_018132.3 40 Aaa/aa 0 +CNOT6 UCSF GRCh37 5 179977041 179977041 + missense_variant Missense_Mutation SNP A A C NOVEL P08_Rec Untested WXS Illumina HiSeq 24 76 152 0 ENST00000261951.4:c.223A>C p.Asn75His p.N75H ENST00000261951 NM_015455.3 75 Aat/Cat 0 +COL12A1 UCSF GRCh37 6 75829108 75829108 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 88 50 196 0 ENST00000322507.8:c.7168G>A p.Ala2390Thr p.A2390T ENST00000322507 NM_004370.5 2390 Gcc/Acc 0 +COL27A1 UCSF GRCh37 9 117002729 117002729 + stop_gained Nonsense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 60 44 101 0 ENST00000356083.3:c.2797C>T p.Arg933Ter p.R933* ENST00000356083 NM_032888.2 933 Cga/Tga 0 +CPNE8 UCSF GRCh37 12 39047732 39047732 + synonymous_variant Silent SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 55 33 95 0 ENST00000331366.5:c.1647G>A p.Ala549= p.A549= ENST00000331366 NM_153634.2 549 gcG/gcA 0 +CSPG4 UCSF GRCh37 15 75982257 75982257 + synonymous_variant Silent SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 30 4 31 1 ENST00000308508.5:c.1149G>A p.Glu383= p.E383= ENST00000308508 NM_001897.4 383 gaG/gaA 0 +CUL9 UCSF GRCh37 6 43190347 43190347 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Rec Untested WXS Illumina HiSeq 16 11 40 0 ENST00000252050.4:c.7000G>T p.Asp2334Tyr p.D2334Y ENST00000252050 NM_015089.2 2334 Gat/Tat 0 +CYSLTR1 UCSF GRCh37 X 77528900 77528900 + missense_variant Missense_Mutation SNP G G C NOVEL P08_Rec Untested WXS Illumina HiSeq 19 44 63 0 ENST00000373304.3:c.344C>G p.Thr115Arg p.T115R ENST00000373304 NM_001282188.1 115 aCa/aGa 0 +DDX60 UCSF GRCh37 4 169194524 169194524 + missense_variant Missense_Mutation SNP G G C NOVEL P08_Rec Untested WXS Illumina HiSeq 13 53 173 0 ENST00000393743.3:c.2480C>G p.Thr827Ser p.T827S ENST00000393743 NM_017631.5 827 aCt/aGt 0 +DTNA UCSF GRCh37 18 32407604 32407604 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 14 119 184 0 ENST00000399113.3:c.1058C>T p.Ser353Phe p.S353F ENST00000399113 353 tCt/tTt 0 +EIF2AK3 UCSF GRCh37 2 88874385 88874385 + synonymous_variant Silent SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 123 89 254 0 ENST00000303236.3:c.2616A>G p.Thr872= p.T872= ENST00000303236 NM_004836.5 872 acA/acG 0 +FANCF UCSF GRCh37 11 22646911 22646911 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 65 55 170 0 ENST00000327470.3:c.446A>G p.Asn149Ser p.N149S ENST00000327470 NM_022725.3 149 aAt/aGt 0 +FCRL6 UCSF GRCh37 1 159779338 159779338 + missense_variant Missense_Mutation SNP C C G NOVEL P08_Rec Untested WXS Illumina HiSeq 42 36 99 0 ENST00000368106.3:c.751C>G p.His251Asp p.H251D ENST00000368106 NM_001004310.2 251 Cac/Gac 0 +GGT7 UCSF GRCh37 20 33440238 33440238 + stop_gained Nonsense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 41 42 92 0 ENST00000336431.5:c.1423C>T p.Gln475Ter p.Q475* ENST00000336431 NM_178026.2 475 Cag/Tag 0 +GNAS UCSF GRCh37 20 57429479 57429479 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 20 14 33 0 ENST00000371100.4:c.1159T>C p.Ser387Pro p.S387P ENST00000371100 NM_001077490.1 387 Tca/Cca 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 92 62 143 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFRD2 UCSF GRCh37 3 50326696 50326696 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 13 8 36 0 ENST00000417626.2:c.875G>A p.Arg292Gln p.R292Q ENST00000417626 NM_006764.4 292 cGg/cAg 0 +IGSF10 UCSF GRCh37 3 151165459 151165459 + missense_variant Missense_Mutation SNP G G C NOVEL P08_Rec Untested WXS Illumina HiSeq 76 63 139 0 ENST00000282466.3:c.2310C>G p.Asp770Glu p.D770E ENST00000282466 NM_178822.4 770 gaC/gaG 0 +INTS1 UCSF GRCh37 7 1515927 1515927 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 13 8 18 0 ENST00000404767.3:c.5316C>T p.Asp1772= p.D1772= ENST00000404767 NM_001080453.2 1772 gaC/gaT 0 +KIAA0564 UCSF GRCh37 13 42295529 42295529 + missense_variant Missense_Mutation SNP C C A NOVEL P08_Rec Untested WXS Illumina HiSeq 109 59 207 1 ENST00000379310.3:c.2941G>T p.Val981Phe p.V981F ENST00000379310 NM_015058.1 981 Gtc/Ttc 0 +LDHB UCSF GRCh37 12 21791391 21791411 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACTCCACACAGCCACTGTTTA ACTCCACACAGCCACTGTTTA CCTCCACACAGCCCCTGTTT NOVEL P08_Rec Untested WXS Illumina HiSeq 8 0 ENST00000350669.1:c.596-7_609delinsAAACAGGGGCTGTGTGGAGG p.X199_splice ENST00000350669 NM_002300.6 0 +MAPK14 UCSF GRCh37 6 35996040 35996040 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Rec Untested WXS Illumina HiSeq 14 11 38 0 ENST00000229794.4:c.106G>T p.Gly36Cys p.G36C ENST00000229794 NM_139012.2 36 Ggc/Tgc 0 +MBNL1 UCSF GRCh37 3 152132729 152132729 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 101 71 151 0 ENST00000282486.6:c.175-1G>A p.X59_splice ENST00000282486 0 +MLLT4 UCSF GRCh37 6 168299038 168299038 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P08_Rec Untested WXS Illumina HiSeq 41 0 ENST00000447894.2:c.1473del p.Phe491LeufsTer27 p.F491Lfs*27 ENST00000447894 491 Ttt/tt 0 +MPO UCSF GRCh37 17 56349077 56349077 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 26 24 75 0 ENST00000225275.3:c.1969G>A p.Val657Met p.V657M ENST00000225275 NM_000250.1 657 Gtg/Atg 0 +MSTN UCSF GRCh37 2 190925003 190925003 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 112 82 204 0 ENST00000260950.4:c.532A>G p.Lys178Glu p.K178E ENST00000260950 NM_005259.2 178 Aaa/Gaa 0 +MUC2 UCSF GRCh37 11 1103572 1103572 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Rec Untested WXS Illumina HiSeq 13 2 23 0 ENST00000441003.2:c.8085G>T p.Met2695Ile p.M2695I ENST00000441003 NM_002457.2 2695 atG/atT 0 +MYF5 UCSF GRCh37 12 81110945 81110945 + stop_gained Nonsense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 34 21 46 0 ENST00000228644.3:c.103C>T p.Arg35Ter p.R35* ENST00000228644 NM_005593.2 35 Cga/Tga 0 +MYO1A UCSF GRCh37 12 57423580 57423580 + stop_gained Nonsense_Mutation SNP C C A NOVEL P08_Rec Untested WXS Illumina HiSeq 72 47 93 0 ENST00000300119.3:c.2668G>T p.Glu890Ter p.E890* ENST00000300119 NM_005379.3 890 Gag/Tag 0 +NKX2-2 UCSF GRCh37 20 21492891 21492892 + inframe_insertion In_Frame_Ins INS - - GAGGCTGGCCAG NOVEL P08_Rec Untested WXS Illumina HiSeq 8 0 ENST00000377142.4:c.492_493insTGGCCAGCCTCC p.Leu164_Ile165insTrpProAlaSer p.L164_I165insWPAS ENST00000377142 NM_002509.3 164 ctc/ctCTGGCCAGCCTCc 0 +NPTX2 UCSF GRCh37 7 98254278 98254278 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 82 78 158 0 ENST00000265634.3:c.688C>T p.Pro230Ser p.P230S ENST00000265634 NM_002523.2 230 Cca/Tca 0 +OR2L2 UCSF GRCh37 1 248202417 248202417 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 166 109 234 0 ENST00000366479.2:c.848T>C p.Met283Thr p.M283T ENST00000366479 NM_001004686.2 283 aTg/aCg 0 +OR51B4 UCSF GRCh37 11 5322448 5322448 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 67 50 163 0 ENST00000380224.1:c.729C>T p.Ser243= p.S243= ENST00000380224 NM_033179.2 243 agC/agT 0 +OR5M9 UCSF GRCh37 11 56230866 56230866 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 29 30 85 0 ENST00000279791.1:c.12C>T p.Phe4= p.F4= ENST00000279791 NM_001004743.1 4 ttC/ttT 0 +OR6N2 UCSF GRCh37 1 158746563 158746563 + missense_variant Missense_Mutation SNP A A T NOVEL P08_Rec Untested WXS Illumina HiSeq 116 86 239 0 ENST00000339258.1:c.863T>A p.Ile288Asn p.I288N ENST00000339258 NM_001005278.1 288 aTt/aAt 0 +PDCL UCSF GRCh37 9 125585446 125585446 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 97 69 178 0 ENST00000259467.4:c.203G>A p.Arg68His p.R68H ENST00000259467 NM_005388.4 68 cGc/cAc 0 +PLD3 UCSF GRCh37 19 40882596 40882596 + stop_gained Nonsense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 33 4 65 0 ENST00000356508.5:c.1100G>A p.Trp367Ter p.W367* ENST00000356508 NM_001031696.2 367 tGg/tAg 0 +PLIN2 UCSF GRCh37 9 19123586 19123586 + missense_variant Missense_Mutation SNP T T A NOVEL P08_Rec Untested WXS Illumina HiSeq 123 72 189 0 ENST00000276914.2:c.286A>T p.Ile96Phe p.I96F ENST00000276914 NM_001122.3 96 Att/Ttt 0 +PRMT5 UCSF GRCh37 14 23396859 23396859 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec somatic WXS Sanger Illumina HiSeq 87 55 110 0 ENST00000324366.8:c.326A>G p.Gln109Arg p.Q109R ENST00000324366 NM_006109.3 109 cAg/cGg 0 +RNASEL UCSF GRCh37 1 182550475 182550475 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 129 105 195 0 ENST00000367559.3:c.1790G>A p.Arg597Gln p.R597Q ENST00000367559 NM_021133.3 597 cGg/cAg 0 +SHISA3 UCSF GRCh37 4 42403378 42403378 + synonymous_variant Silent SNP T T G NOVEL P08_Rec Untested WXS Illumina HiSeq 61 25 101 0 ENST00000319234.4:c.627T>G p.Gly209= p.G209= ENST00000319234 NM_001080505.1 209 ggT/ggG 0 +SLC6A13 UCSF GRCh37 12 332297 332297 + splice_donor_variant Splice_Site SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 29 16 63 0 ENST00000343164.4:c.1414+1G>A p.X472_splice ENST00000343164 NM_016615.4 0 +SLC6A3 UCSF GRCh37 5 1441532 1441532 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 26 18 59 0 ENST00000270349.9:c.360C>T p.Leu120= p.L120= ENST00000270349 NM_001044.4 120 ctC/ctT 0 +SSC5D UCSF GRCh37 19 56001358 56001358 + synonymous_variant Silent SNP A A T NOVEL P08_Rec Untested WXS Illumina HiSeq 3 11 30 0 ENST00000389623.6:c.471A>T p.Thr157= p.T157= ENST00000389623 NM_001144950.1 157 acA/acT 0 +TBCE UCSF GRCh37 1 235600735 235600735 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 57 37 97 0 ENST00000366601.3:c.1062G>A p.Ala354= p.A354= ENST00000366601 354 gcG/gcA 0 +TCP10L2 UCSF GRCh37 6 167585753 167585753 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Rec Untested WXS Illumina HiSeq 27 5 46 0 ENST00000366832.2:c.121G>T p.Asp41Tyr p.D41Y ENST00000366832 NM_001145121.1 41 Gac/Tac 0 +TNRC6A UCSF GRCh37 16 24802604 24802604 + missense_variant Missense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 74 60 153 0 ENST00000395799.3:c.2641G>A p.Asp881Asn p.D881N ENST00000395799 NM_014494.2 881 Gac/Aac 0 +TP53 UCSF GRCh37 17 7577099 7577099 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 7 81 65 0 ENST00000269305.4:c.839G>A p.Arg280Lys p.R280K ENST00000269305 NM_001126112.2 280 aGa/aAa 0 +TTLL3 UCSF GRCh37 3 9852311 9852311 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 15 3 23 0 ENST00000426895.4:c.395C>T p.Pro132Leu p.P132L ENST00000426895 132 cCg/cTg 0 +TTN UCSF GRCh37 2 179568917 179568917 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 127 91 255 0 ENST00000591111.1:c.29229C>T p.Cys9743= p.C9743= ENST00000591111 9743 tgC/tgT 0 +USH2A UCSF GRCh37 1 215901628 215901628 + missense_variant Missense_Mutation SNP A A G NOVEL P08_Rec Untested WXS Illumina HiSeq 85 53 179 0 ENST00000307340.3:c.11810T>C p.Leu3937Pro p.L3937P ENST00000307340 NM_206933.2 3937 cTc/cCc 0 +USH2A UCSF GRCh37 1 216144109 216144109 + missense_variant Missense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 189 27 196 0 ENST00000307340.3:c.6815C>T p.Thr2272Met p.T2272M ENST00000307340 NM_206933.2 2272 aCg/aTg 0 +USH2A UCSF GRCh37 1 216363700 216363700 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 108 66 185 0 ENST00000307340.3:c.4261A>G p.Thr1421Ala p.T1421A ENST00000307340 NM_206933.2 1421 Act/Gct 0 +USP29 UCSF GRCh37 19 57640261 57640261 + missense_variant Missense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 78 9 127 0 ENST00000254181.4:c.218G>A p.Arg73His p.R73H ENST00000254181 NM_020903.2 73 cGt/cAt 0 +WBSCR28 UCSF GRCh37 7 73279585 73279585 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 46 6 38 0 ENST00000320531.2:c.335C>T p.Ala112Val p.A112V ENST00000320531 NM_182504.3 112 gCc/gTc 0 +WDR63 UCSF GRCh37 1 85583512 85583512 + missense_variant Missense_Mutation SNP C C G NOVEL P08_Rec Untested WXS Illumina HiSeq 102 85 194 0 ENST00000294664.6:c.1887C>G p.Asp629Glu p.D629E ENST00000294664 NM_145172.3 629 gaC/gaG 0 +WT1 UCSF GRCh37 11 32449529 32449529 + missense_variant Missense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 11 6 17 0 ENST00000332351.3:c.845C>T p.Ala282Val p.A282V ENST00000332351 NM_024426.4 282 gCt/gTt 0 +XPO6 UCSF GRCh37 16 28146612 28146612 + synonymous_variant Silent SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 70 50 114 0 ENST00000304658.5:c.1368G>A p.Glu456= p.E456= ENST00000304658 NM_015171.3 456 gaG/gaA 0 +ZNF596 UCSF GRCh37 8 193006 193006 + synonymous_variant Silent SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 67 36 89 0 ENST00000308811.4:c.132C>T p.Val44= p.V44= ENST00000308811 NM_173539.2 44 gtC/gtT 0 +ZNF804B UCSF GRCh37 7 88962812 88962812 + synonymous_variant Silent SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 98 75 209 0 ENST00000333190.4:c.516T>C p.Asn172= p.N172= ENST00000333190 NM_181646.2 172 aaT/aaC 0 +ATRX UCSF GRCh37 X 76954101 76954101 + synonymous_variant Silent SNP A A G NOVEL P09_Pri Untested WXS Illumina HiSeq 8 56 69 0 ENST00000373344.5:c.150T>C p.Ser50= p.S50= ENST00000373344 NM_000489.3 50 tcT/tcC 0 +GAGE2D UCSF GRCh37 X 49208299 49208313 + protein_altering_variant In_Frame_Ins INS CGGCCTAGACCAAGA CGGCCTAGACCAAGA TATTGGCCTAGACCAAGG NOVEL P09_Pri Untested WXS Illumina HiSeq 8 0 ENST00000404720.2:c.28_42delinsTATTGGCCTAGACCAAGG p.Arg10delinsTyrTrp p.R10delinsYW ENST00000404720 NM_001098407.1 10 CGGCCTAGACCAAGA/TATTGGCCTAGACCAAGG 0 +GOLGA6B UCSF GRCh37 15 72954702 72954702 + synonymous_variant Silent SNP A A G snp132_rs74793989 P09_Pri Untested WXS Illumina HiSeq 29 4 76 1 ENST00000421285.3:c.957A>G p.Gln319= p.Q319= ENST00000421285 NM_018652.4 319 caA/caG 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P09_Pri Untested WXS Illumina HiSeq 47 40 81 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +OR4C6 UCSF GRCh37 11 55433016 55433016 + missense_variant Missense_Mutation SNP G G T NOVEL P09_Pri somatic WXS Sanger Illumina HiSeq 59 22 107 0 ENST00000314259.3:c.374G>T p.Cys125Phe p.C125F ENST00000314259 NM_001004704.1 125 tGt/tTt 0 +PDE4DIP UCSF GRCh37 1 144886132 144886132 + synonymous_variant Silent SNP A A G NOVEL P09_Pri Untested WXS Illumina HiSeq 91 33 144 0 ENST00000369354.3:c.3102T>C p.Ile1034= p.I1034= ENST00000369354 1034 atT/atC 0 +SLC38A10 UCSF GRCh37 17 79268677 79268677 + synonymous_variant Silent SNP G G A NOVEL P09_Pri Untested WXS Illumina HiSeq 29 11 35 0 ENST00000374759.3:c.45C>T p.Ile15= p.I15= ENST00000374759 NM_001037984.1 15 atC/atT 0 +TP53 UCSF GRCh37 17 7578479 7578479 + missense_variant Missense_Mutation SNP G G C NOVEL P09_Pri Untested WXS Illumina HiSeq 4 32 48 0 ENST00000269305.4:c.451C>G p.Pro151Ala p.P151A ENST00000269305 NM_001126112.2 151 Ccc/Gcc 0 +UGT2A3 UCSF GRCh37 4 69817137 69817138 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P09_Pri Untested WXS Illumina HiSeq 12 0 ENST00000251566.4:c.342dup p.Val115CysfsTer2 p.V115Cfs*2 ENST00000251566 NM_024743.3 114 ttt/ttTt 0 +ABCB4 UCSF GRCh37 7 87079392 87079392 + missense_variant Missense_Mutation SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 124 49 92 0 ENST00000265723.4:c.725G>A p.Ser242Asn p.S242N ENST00000265723 NM_000443.3 242 aGt/aAt 0 +ASB14 UCSF GRCh37 3 57322030 57322030 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P09_Rec Untested WXS Illumina HiSeq 6 0 ENST00000389601.3:c.371del p.Leu124TrpfsTer8 p.L124Wfs*8 ENST00000389601 NM_130387.5 124 tTg/tg 0 +ATRX UCSF GRCh37 X 76954101 76954101 + synonymous_variant Silent SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 71 42 69 0 ENST00000373344.5:c.150T>C p.Ser50= p.S50= ENST00000373344 NM_000489.3 50 tcT/tcC 0 +C17orf97 UCSF GRCh37 17 263615 263615 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0396,snp132_rs75457484 P09_Rec Untested WXS Illumina HiSeq 45 6 23 1 ENST00000360127.6:c.981C>T p.Pro327= p.P327= ENST00000360127 NM_001013672.4 327 ccC/ccT 0 +CCHCR1 UCSF GRCh37 6 31113527 31113527 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 89 40 49 1 ENST00000376266.5:c.1372C>T p.Pro458Ser p.P458S ENST00000376266 NM_019052.3 458 Ccc/Tcc 0 +DYSF UCSF GRCh37 2 71896760 71896760 + missense_variant Missense_Mutation SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 130 46 99 0 ENST00000258104.3:c.5551A>G p.Lys1851Glu p.K1851E ENST00000258104 NM_003494.3 1851 Aag/Gag 0 +DYSF UCSF GRCh37 2 71896763 71896763 + missense_variant Missense_Mutation SNP C C G NOVEL P09_Rec Untested WXS Illumina HiSeq 126 46 97 0 ENST00000258104.3:c.5554C>G p.Gln1852Glu p.Q1852E ENST00000258104 NM_003494.3 1852 Caa/Gaa 0 +FAM46B UCSF GRCh37 1 27333030 27333038 + frameshift_variant Frame_Shift_Del DEL AGCAACAGG AGCAACAGG CGACA NOVEL P09_Rec Untested WXS Illumina HiSeq 14 0 ENST00000289166.5:c.675_683delinsTGTCG p.Leu226ValfsTer97 p.L226Vfs*97 ENST00000289166 NM_052943.3 225 tcCCTGTTGCTc/tcTGTCGc 0 +FAM48B2 UCSF GRCh37 X 24330042 24330042 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 16 6 18 0 ENST00000536351.1:n.1391G>A *464* ENST00000536351 0 +GAGE2D UCSF GRCh37 X 49208299 49208313 + protein_altering_variant In_Frame_Ins INS CGGCCTAGACCAAGA CGGCCTAGACCAAGA TATTGGCCTAGACCAAGG NOVEL P09_Rec Untested WXS Illumina HiSeq 6 0 ENST00000404720.2:c.28_42delinsTATTGGCCTAGACCAAGG p.Arg10delinsTyrTrp p.R10delinsYW ENST00000404720 NM_001098407.1 10 CGGCCTAGACCAAGA/TATTGGCCTAGACCAAGG 0 +HHIP UCSF GRCh37 4 145580034 145580034 + missense_variant Missense_Mutation SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 95 22 117 0 ENST00000296575.3:c.565A>G p.Arg189Gly p.R189G ENST00000296575 NM_022475.2 189 Aga/Gga 0 +HLA-C UCSF GRCh37 6 31239060 31239060 + missense_variant Missense_Mutation SNP A A G 1000g2010nov_all_0.113,1000g2011may_all_0.1122,snp132_rs114934942 P09_Rec Untested WXS Illumina HiSeq 50 16 31 1 ENST00000376228.5:c.409T>C p.Tyr137His p.Y137H ENST00000376228 NM_002117.5 137 Tat/Cat 0 +HLA-G UCSF GRCh37 6 29797406 29797406 + synonymous_variant Silent SNP G G A snp132_rs79264452 P09_Rec Untested WXS Illumina HiSeq 117 18 90 1 ENST00000360323.6:c.831G>A p.Glu277= p.E277= ENST00000360323 277 gaG/gaA 0 +HLA-G UCSF GRCh37 6 29797436 29797436 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.113,snp132_rs115797657 P09_Rec Untested WXS Illumina HiSeq 110 18 74 1 ENST00000360323.6:c.861T>C p.His287= p.H287= ENST00000360323 287 caT/caC 0 +HOXB2 UCSF GRCh37 17 46622047 46622047 + missense_variant Missense_Mutation SNP G G C NOVEL P09_Rec Untested WXS Illumina HiSeq 34 5 36 0 ENST00000330070.4:c.227C>G p.Pro76Arg p.P76R ENST00000330070 NM_002145.3 76 cCt/cGt 0 +ICK UCSF GRCh37 6 52880927 52880927 + missense_variant Missense_Mutation SNP C C G NOVEL P09_Rec Untested WXS Illumina HiSeq 120 32 107 0 ENST00000350082.5:c.785G>C p.Arg262Thr p.R262T ENST00000350082 NM_014920.3 262 aGa/aCa 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 119 30 81 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGF2 UCSF GRCh37 11 2154787 2154794 + frameshift_variant Frame_Shift_Del DEL TTGGCGGG TTGGCGGG - NOVEL P09_Rec Untested WXS Illumina HiSeq 10 0 ENST00000300632.5:c.259_266del p.Pro87ValfsTer28 p.P87Vfs*28 ENST00000300632 NM_001007139.4 87 CCCGCCAAg/g 0 +INTS6 UCSF GRCh37 13 51957526 51957529 + frameshift_variant Frame_Shift_Del DEL TGCT TGCT - NOVEL P09_Rec Untested WXS Illumina HiSeq 17 0 ENST00000311234.4:c.1116_1119del p.Ala373Ter p.A373* ENST00000311234 NM_012141.2 372 acAGCA/ac 0 +JARID2 UCSF GRCh37 6 15468893 15468893 + missense_variant Missense_Mutation SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 187 61 85 0 ENST00000341776.2:c.614C>T p.Ser205Leu p.S205L ENST00000341776 NM_004973.3 205 tCa/tTa 0 +MUC4 UCSF GRCh37 3 195507919 195507919 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 36 9 57 1 ENST00000463781.3:c.10532C>T p.Ser3511Phe p.S3511F ENST00000463781 NM_018406.6 3511 tCc/tTc 0 +NUDT10 UCSF GRCh37 X 51075841 51075841 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.07393,1000g2011may_all_0.2097,snp132_rs2625875 P09_Rec Untested WXS Illumina HiSeq 28 4 19 0 ENST00000356450.2:c.24A>G p.Thr8= p.T8= ENST00000356450 8 acA/acG 0 +NUDT10 UCSF GRCh37 X 51076024 51076024 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.00397,1000g2011may_all_0.0126,snp132_rs2801626 P09_Rec Untested WXS Illumina HiSeq 36 4 34 0 ENST00000356450.2:c.207G>A p.Glu69= p.E69= ENST00000356450 69 gaG/gaA 0 +OAS2 UCSF GRCh37 12 113448284 113448309 + stop_lost,3_prime_UTR_variant Nonstop_Mutation DEL TTCTAGAGATCATCTGGCAATCGCTT TTCTAGAGATCATCTGGCAATCGCTT - NOVEL P09_Rec Untested WXS Illumina HiSeq 26 0 ENST00000342315.4:c.2157_*22del *719* ENST00000342315 NM_016817.2 719 0 +OR10C1 UCSF GRCh37 6 29408542 29408542 + missense_variant Missense_Mutation SNP C C G NOVEL P09_Rec Untested WXS Illumina HiSeq 165 105 115 0 ENST00000444197.2:c.750C>G p.Phe250Leu p.F250L ENST00000444197 NM_013941.3 250 ttC/ttG 0 +OR11G2 UCSF GRCh37 14 20665692 20665692 + synonymous_variant Silent SNP T T C NOVEL P09_Rec Untested WXS Illumina HiSeq 87 36 66 0 ENST00000357366.3:c.198T>C p.Phe66= p.F66= ENST00000357366 NM_001005503.1 66 ttT/ttC 0 +OR4C6 UCSF GRCh37 11 55433016 55433016 + missense_variant Missense_Mutation SNP G G T NOVEL P09_Rec somatic WXS Sanger Illumina HiSeq 87 41 107 0 ENST00000314259.3:c.374G>T p.Cys125Phe p.C125F ENST00000314259 NM_001004704.1 125 tGt/tTt 0 +PCF11 UCSF GRCh37 11 82877718 82877718 + synonymous_variant Silent SNP T T C NOVEL P09_Rec Untested WXS Illumina HiSeq 179 131 184 0 ENST00000298281.4:c.1779T>C p.Ser593= p.S593= ENST00000298281 NM_015885.3 593 tcT/tcC 0 +PDE4DIP UCSF GRCh37 1 144886132 144886132 + synonymous_variant Silent SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 171 32 144 0 ENST00000369354.3:c.3102T>C p.Ile1034= p.I1034= ENST00000369354 1034 atT/atC 0 +PHF3 UCSF GRCh37 6 64419048 64419048 + missense_variant,splice_region_variant Missense_Mutation SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 91 36 82 0 ENST00000262043.3:c.3713A>G p.Asp1238Gly p.D1238G ENST00000262043 1238 gAc/gGc 0 +PPFIBP1 UCSF GRCh37 12 27825398 27825415 + inframe_deletion,splice_region_variant In_Frame_Del DEL AACTGTGTGATAAACTTT AACTGTGTGATAAACTTT - NOVEL P09_Rec Untested WXS Illumina HiSeq 9 0 ENST00000318304.8:c.1352_1369del p.Gln451_Leu456del p.Q451_L456del ENST00000318304 NM_177444.2 451 cAACTGTGTGATAAACTTTta/cta 0 +PSMD5 UCSF GRCh37 9 123595695 123595695 + synonymous_variant Silent SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 164 82 134 0 ENST00000210313.3:c.213G>A p.Leu71= p.L71= ENST00000210313 NM_005047.3 71 ttG/ttA 0 +SLC28A2 UCSF GRCh37 15 45561641 45561641 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 111 25 96 0 ENST00000347644.3:c.1474G>A p.Glu492Lys p.E492K ENST00000347644 NM_004212.3 492 Gag/Aag 0 +SLC28A2 UCSF GRCh37 15 45561643 45561643 + missense_variant Missense_Mutation SNP G G T NOVEL P09_Rec Untested WXS Illumina HiSeq 114 26 97 0 ENST00000347644.3:c.1476G>T p.Glu492Asp p.E492D ENST00000347644 NM_004212.3 492 gaG/gaT 0 +SLC38A10 UCSF GRCh37 17 79268677 79268677 + synonymous_variant Silent SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 41 14 35 0 ENST00000374759.3:c.45C>T p.Ile15= p.I15= ENST00000374759 NM_001037984.1 15 atC/atT 0 +TAOK3 UCSF GRCh37 12 118588939 118588939 + missense_variant Missense_Mutation SNP G G T NOVEL P09_Rec Untested WXS Illumina HiSeq 102 36 82 0 ENST00000392533.3:c.2560C>A p.Gln854Lys p.Q854K ENST00000392533 NM_016281.3 854 Cag/Aag 0 +TAOK3 UCSF GRCh37 12 118588940 118588940 + synonymous_variant Silent SNP A A T NOVEL P09_Rec Untested WXS Illumina HiSeq 101 36 82 0 ENST00000392533.3:c.2559T>A p.Leu853= p.L853= ENST00000392533 NM_016281.3 853 ctT/ctA 0 +TEX11 UCSF GRCh37 X 70093131 70093131 + missense_variant Missense_Mutation SNP C C A NOVEL P09_Rec Untested WXS Illumina HiSeq 38 33 52 0 ENST00000344304.3:c.231G>T p.Trp77Cys p.W77C ENST00000344304 77 tgG/tgT 0 +TMED1 UCSF GRCh37 19 10945980 10945980 + missense_variant Missense_Mutation SNP T T C NOVEL P09_Rec Untested WXS Illumina HiSeq 72 20 54 0 ENST00000214869.2:c.233A>G p.Gln78Arg p.Q78R ENST00000214869 NM_006858.3 78 cAg/cGg 0 +TNF UCSF GRCh37 6 31544909 31544909 + synonymous_variant Silent SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 110 38 64 0 ENST00000449264.2:c.297G>A p.Glu99= p.E99= ENST00000449264 NM_000594.3 99 gaG/gaA 0 +TNF UCSF GRCh37 6 31545161 31545161 + synonymous_variant Silent SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 112 29 65 0 ENST00000449264.2:c.549G>A p.Glu183= p.E183= ENST00000449264 NM_000594.3 183 gaG/gaA 0 +TNNI1 UCSF GRCh37 1 201380601 201380601 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 47 8 42 0 ENST00000336092.4:c.340C>T p.Arg114Cys p.R114C ENST00000336092 114 Cgt/Tgt 0 +TNNT3 UCSF GRCh37 11 1955222 1955222 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 21 13 33 0 ENST00000397301.1:c.383G>A p.Arg128His p.R128H ENST00000397301 128 cGc/cAc 0 +TP53 UCSF GRCh37 17 7578479 7578479 + missense_variant Missense_Mutation SNP G G C NOVEL P09_Rec Untested WXS Illumina HiSeq 31 38 48 0 ENST00000269305.4:c.451C>G p.Pro151Ala p.P151A ENST00000269305 NM_001126112.2 151 Ccc/Gcc 0 +UNC13A UCSF GRCh37 19 17756853 17756853 + missense_variant Missense_Mutation SNP C C G NOVEL P09_Rec Untested WXS Illumina HiSeq 92 54 58 0 ENST00000519716.2:c.2112G>C p.Gln704His p.Q704H ENST00000519716 NM_001080421.2 704 caG/caC 0 +UNC93B1 UCSF GRCh37 11 67763353 67763353 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 35 7 22 1 ENST00000227471.2:c.1089C>T p.Gly363= p.G363= ENST00000227471 NM_030930.2 363 ggC/ggT 0 +USP28 UCSF GRCh37 11 113672332 113672335 + frameshift_variant Frame_Shift_Del DEL ATTA ATTA - NOVEL P09_Rec Untested WXS Illumina HiSeq 26 0 ENST00000003302.4:c.2928_2931del p.Ile976MetfsTer2 p.I976Mfs*2 ENST00000003302 NM_020886.2 976 atTAAT/at 0 +VPS35 UCSF GRCh37 16 46708258 46708258 + synonymous_variant Silent SNP T T C NOVEL P09_Rec Untested WXS Illumina HiSeq 88 40 78 0 ENST00000299138.7:c.1128A>G p.Thr376= p.T376= ENST00000299138 NM_018206.4 376 acA/acG 0 +ZNF292 UCSF GRCh37 6 87965102 87965103 + frameshift_variant Frame_Shift_Ins INS - - C NOVEL P09_Rec Untested WXS Illumina HiSeq 45 0 ENST00000369577.3:c.1757dup p.His587SerfsTer7 p.H587Sfs*7 ENST00000369577 NM_015021.1 585 -/C 0 +ABCD1 UCSF GRCh37 X 152991314 152991314 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri somatic WXS Sanger Illumina HiSeq 12 20 108 0 ENST00000218104.3:c.593C>T p.Thr198Met p.T198M ENST00000218104 NM_000033.3 198 aCg/aTg 0 +ADCK4 UCSF GRCh37 19 41208533 41208533 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 37 29 92 0 ENST00000324464.3:c.865C>T p.Arg289Cys p.R289C ENST00000324464 NM_024876.3 289 Cgt/Tgt 0 +ARHGEF9 UCSF GRCh37 X 62858032 62858032 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Pri Untested WXS Illumina HiSeq 11 12 49 0 ENST00000253401.6:c.1427A>G p.Asn476Ser p.N476S ENST00000253401 NM_015185.2 476 aAc/aGc 0 +ASPSCR1 UCSF GRCh37 17 79968702 79968702 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 13 9 55 1 ENST00000306739.4:c.1195G>A p.Asp399Asn p.D399N ENST00000306739 NM_024083.3 399 Gac/Aac 0 +ATRX UCSF GRCh37 X 76814225 76814225 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Pri somatic WXS Sanger Illumina HiSeq 52 42 168 0 ENST00000373344.5:c.6419A>G p.Asn2140Ser p.N2140S ENST00000373344 NM_000489.3 2140 aAt/aGt 0 +CCDC151 UCSF GRCh37 19 11537720 11537720 + synonymous_variant Silent SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 13 12 52 0 ENST00000356392.4:c.585G>A p.Ala195= p.A195= ENST00000356392 NM_145045.4 195 gcG/gcA 0 +DAGLA UCSF GRCh37 11 61505189 61505189 + synonymous_variant Silent SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 40 17 82 0 ENST00000257215.5:c.1545C>T p.Phe515= p.F515= ENST00000257215 NM_006133.2 515 ttC/ttT 0 +DSCAM UCSF GRCh37 21 41684176 41684176 + stop_gained Nonsense_Mutation SNP T T A NOVEL P10_Pri Untested WXS Illumina HiSeq 52 16 136 0 ENST00000400454.1:c.1894A>T p.Lys632Ter p.K632* ENST00000400454 NM_001271534.1 632 Aag/Tag 0 +FAM55A UCSF GRCh37 11 114392826 114392826 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Pri Untested WXS Illumina HiSeq 62 28 186 0 ENST00000424269.1:c.1508A>G p.Lys503Arg p.K503R ENST00000424269 503 aAg/aGg 0 +FAM75C2 UCSF GRCh37 9 90746733 90746733 + non_coding_transcript_exon_variant RNA SNP C C G NOVEL P10_Pri Untested WXS Illumina HiSeq 43 25 267 1 ENST00000428649.2:n.1248G>C *416* ENST00000428649 0 +FLG UCSF GRCh37 1 152280068 152280068 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 30 26 214 0 ENST00000368799.1:c.7294G>A p.Gly2432Arg p.G2432R ENST00000368799 NM_002016.1 2432 Ggg/Agg 0 +FRMPD4 UCSF GRCh37 X 12734380 12734380 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Pri Untested WXS Illumina HiSeq 44 36 188 1 ENST00000380682.1:c.1802A>G p.Tyr601Cys p.Y601C ENST00000380682 NM_014728.3 601 tAt/tGt 0 +GABRE UCSF GRCh37 X 151123325 151123325 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Pri Untested WXS Illumina HiSeq 24 13 57 0 ENST00000370328.3:c.1369T>C p.Phe457Leu p.F457L ENST00000370328 NM_004961.3 457 Ttc/Ctc 0 +GTPBP1 UCSF GRCh37 22 39123237 39123237 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 7 33 150 1 ENST00000216044.5:c.1421G>A p.Arg474Gln p.R474Q ENST00000216044 NM_004286.4 474 cGg/cAg 0 +HS3ST3A1 UCSF GRCh37 17 13400067 13400067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 35 16 124 0 ENST00000284110.1:c.668G>A p.Arg223Gln p.R223Q ENST00000284110 NM_006042.1 223 cGg/cAg 0 +HS3ST3B1 UCSF GRCh37 17 14248413 14248413 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 2 14 46 0 ENST00000360954.2:c.623G>A p.Arg208Gln p.R208Q ENST00000360954 NM_006041.1 208 cGg/cAg 0 +HTRA1 UCSF GRCh37 10 124248504 124248504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 31 33 132 0 ENST00000368984.3:c.559G>A p.Glu187Lys p.E187K ENST00000368984 NM_002775.4 187 Gaa/Aaa 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri somatic WXS Sanger Illumina HiSeq 56 46 125 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KCNJ12 UCSF GRCh37 17 21319232 21319232 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 61 10 115 0 ENST00000331718.5:c.578C>T p.Thr193Met p.T193M ENST00000331718 NM_001194958.2 193 aCg/aTg 0 +KRTAP4-1 UCSF GRCh37 17 39340795 39340795 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.020 P10_Pri Untested WXS Illumina HiSeq 34 6 97 1 ENST00000398472.1:c.312T>C p.Arg104= p.R104= ENST00000398472 104 cgT/cgC 0 +LCA5L UCSF GRCh37 21 40800200 40800200 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 67 8 182 0 ENST00000288350.3:c.220G>A p.Asp74Asn p.D74N ENST00000288350 74 Gat/Aat 0 +MYH1 UCSF GRCh37 17 10406468 10406468 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Pri Untested WXS Illumina HiSeq 18 24 218 1 ENST00000226207.5:c.2789C>A p.Ala930Asp p.A930D ENST00000226207 NM_005963.3 930 gCt/gAt 0 +MYH14 UCSF GRCh37 19 50795615 50795615 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Pri Untested WXS Illumina HiSeq 21 4 36 2 ENST00000376970.2:c.5201G>T p.Gly1734Val p.G1734V ENST00000376970 NM_024729.3 1734 gGc/gTc 0 +NBPF4 UCSF GRCh37 1 108769307 108769307 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.062,1000g2011may_all_0.2082,snp132_rs2582071 P10_Pri Untested WXS Illumina HiSeq 34 5 70 1 ENST00000415641.3:c.1869C>T p.Ser623= p.S623= ENST00000415641 NM_001143989.2 623 agC/agT 0 +NLGN4X UCSF GRCh37 X 5821576 5821576 + synonymous_variant Silent SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 26 23 150 0 ENST00000275857.6:c.1143C>T p.Asp381= p.D381= ENST00000275857 NM_020742.2 381 gaC/gaT 0 +OR4K15 UCSF GRCh37 14 20444624 20444624 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Pri Untested WXS Illumina HiSeq 36 26 172 0 ENST00000305051.5:c.947A>G p.Lys316Arg p.K316R ENST00000305051 NM_001005486.1 316 aAa/aGa 0 +PLXNA4 UCSF GRCh37 7 131831322 131831322 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 51 25 172 0 ENST00000321063.4:c.5002C>T p.Arg1668Trp p.R1668W ENST00000321063 NM_020911.1 1668 Cgg/Tgg 0 +PTK2 UCSF GRCh37 8 141829029 141829043 + inframe_deletion In_Frame_Del DEL GGATCTCAAAGAATT GGATCTCAAAGAATT - NOVEL P10_Pri Untested WXS Illumina HiSeq 109 0 ENST00000521059.1:c.725_739del p.Lys242_Leu247delinsMet p.K242_L247delinsM ENST00000521059 NM_005607.4 242 aAATTCTTTGAGATCCtg/atg 0 +S100PBP UCSF GRCh37 1 33292145 33292145 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Pri Untested WXS Illumina HiSeq 62 38 175 0 ENST00000373475.5:c.445G>T p.Ala149Ser p.A149S ENST00000373475 NM_022753.3 149 Gca/Tca 0 +SORBS2 UCSF GRCh37 4 186544879 186544879 + synonymous_variant Silent SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 43 23 118 0 ENST00000284776.7:c.1692C>T p.Pro564= p.P564= ENST00000284776 NM_021069.4 564 ccC/ccT 0 +SSBP2 UCSF GRCh37 5 80733256 80733256 + missense_variant Missense_Mutation SNP A A C NOVEL P10_Pri Untested WXS Illumina HiSeq 70 38 164 0 ENST00000320672.4:c.950T>G p.Ile317Ser p.I317S ENST00000320672 NM_001256732.1 317 aTt/aGt 0 +TMEM214 UCSF GRCh37 2 27261943 27261943 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 23 7 90 0 ENST00000238788.9:c.1436G>A p.Arg479Gln p.R479Q ENST00000238788 NM_017727.4 479 cGg/cAg 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri somatic WXS Sanger Illumina HiSeq 3 24 83 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TRIM42 UCSF GRCh37 3 140407071 140407071 + missense_variant Missense_Mutation SNP T T G NOVEL P10_Pri Untested WXS Illumina HiSeq 38 18 156 0 ENST00000286349.3:c.1547T>G p.Ile516Ser p.I516S ENST00000286349 NM_152616.4 516 aTt/aGt 0 +ZDHHC18 UCSF GRCh37 1 27177632 27177632 + synonymous_variant Silent SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 18 18 122 0 ENST00000374142.4:c.846G>A p.Leu282= p.L282= ENST00000374142 NM_032283.2 282 ttG/ttA 0 +ZNF527 UCSF GRCh37 19 37880574 37880574 + synonymous_variant Silent SNP T T C NOVEL P10_Pri Untested WXS Illumina HiSeq 53 41 132 0 ENST00000436120.2:c.1623T>C p.Leu541= p.L541= ENST00000436120 NM_032453.1 541 ctT/ctC 0 +A2ML1 UCSF GRCh37 12 8975830 8975830 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 77 173 0 ENST00000299698.7:c.115G>A p.Val39Ile p.V39I ENST00000299698 NM_144670.4 39 Gtt/Att 0 +AAMP UCSF GRCh37 2 219131576 219131576 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 51 94 0 ENST00000248450.4:c.528C>T p.Asp176= p.D176= ENST00000248450 176 gaC/gaT 0 +AANAT UCSF GRCh37 17 74465899 74465899 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 8 14 0 ENST00000392492.3:c.471G>A p.Ala157= p.A157= ENST00000392492 NM_001088.2 157 gcG/gcA 0 +ABAT UCSF GRCh37 16 8866640 8866640 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 42 140 0 ENST00000268251.8:c.820G>A p.Glu274Lys p.E274K ENST00000268251 NM_020686.5 274 Gag/Aag 0 +ABCA1 UCSF GRCh37 9 107588071 107588071 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 189 72 168 0 ENST00000374736.3:c.2435G>A p.Ser812Asn p.S812N ENST00000374736 NM_005502.3 812 aGt/aAt 0 +ABCA13 UCSF GRCh37 7 48318903 48318903 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 77 98 0 ENST00000435803.1:c.8112C>T p.Gly2704= p.G2704= ENST00000435803 NM_152701.3 2704 ggC/ggT 0 +ABCA2 UCSF GRCh37 9 139910305 139910305 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 21 43 0 ENST00000341511.6:c.3336G>A p.Glu1112= p.E1112= ENST00000341511 NM_212533.2 1112 gaG/gaA 0 +ABCA5 UCSF GRCh37 17 67260942 67260942 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 38 124 0 ENST00000392676.3:c.3249G>A p.Leu1083= p.L1083= ENST00000392676 1083 ttG/ttA 0 +ABCA9 UCSF GRCh37 17 67031836 67031836 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 83 153 0 ENST00000340001.4:c.907G>A p.Val303Ile p.V303I ENST00000340001 NM_080283.3 303 Gtc/Atc 0 +ABCB1 UCSF GRCh37 7 87168620 87168620 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 35 87 0 ENST00000265724.3:c.2361G>A p.Arg787= p.R787= ENST00000265724 NM_000927.4 787 cgG/cgA 0 +ABCB4 UCSF GRCh37 7 87076349 87076349 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 37 87 0 ENST00000265723.4:c.1005+1G>A p.X335_splice ENST00000265723 NM_000443.3 0 +ABCC11 UCSF GRCh37 16 48220964 48220964 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 75 157 0 ENST00000356608.2:c.2971G>A p.Glu991Lys p.E991K ENST00000356608 991 Gag/Aag 0 +ABCC11 UCSF GRCh37 16 48264461 48264461 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 38 81 0 ENST00000356608.2:c.123C>T p.Gly41= p.G41= ENST00000356608 41 ggC/ggT 0 +ABCC2 UCSF GRCh37 10 101567257 101567257 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 59 139 0 ENST00000370449.4:c.1647C>T p.Val549= p.V549= ENST00000370449 NM_000392.3 549 gtC/gtT 0 +ABCC3 UCSF GRCh37 17 48765012 48765012 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 70 146 0 ENST00000285238.8:c.4396G>A p.Ala1466Thr p.A1466T ENST00000285238 NM_003786.3 1466 Gct/Act 0 +ABCD1 UCSF GRCh37 X 152991314 152991314 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 58 58 108 0 ENST00000218104.3:c.593C>T p.Thr198Met p.T198M ENST00000218104 NM_000033.3 198 aCg/aTg 0 +ABHD11 UCSF GRCh37 7 73152057 73152057 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 23 48 0 ENST00000222800.3:c.297G>A p.Thr99= p.T99= ENST00000222800 NM_148912.2 99 acG/acA 0 +ABHD12 UCSF GRCh37 20 25275646 25275646 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 58 153 0 ENST00000376542.3:c.1178C>T p.Ser393Phe p.S393F ENST00000376542 NM_015600.4 393 tCc/tTc 0 +ABHD14B UCSF GRCh37 3 52004156 52004156 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 54 94 0 ENST00000361143.5:c.256G>A p.Glu86Lys p.E86K ENST00000361143 86 Gag/Aag 0 +ABL1 UCSF GRCh37 9 133760004 133760004 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 72 28 47 0 ENST00000318560.5:c.2327C>T p.Thr776Ile p.T776I ENST00000318560 NM_005157.4 776 aCc/aTc 0 +ABL1 UCSF GRCh37 9 133750256 133750256 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 142 66 163 0 ENST00000318560.5:c.1087G>A p.Asp363Asn p.D363N ENST00000318560 NM_005157.4 363 Gat/Aat 0 +ABT1 UCSF GRCh37 6 26598177 26598177 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 44 75 0 ENST00000274849.1:c.277G>A p.Ala93Thr p.A93T ENST00000274849 NM_013375.3 93 Gct/Act 0 +ACAD11 UCSF GRCh37 3 132322080 132322080 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 66 173 0 ENST00000264990.6:c.1614G>A p.Trp538Ter p.W538* ENST00000264990 NM_032169.4 538 tgG/tgA 0 +ACAP1 UCSF GRCh37 17 7247260 7247260 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 22 24 1 ENST00000158762.3:c.654G>A p.Lys218= p.K218= ENST00000158762 NM_014716.3 218 aaG/aaA 0 +ACCN3 UCSF GRCh37 7 150746101 150746101 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 66 89 0 ENST00000349064.5:c.129G>A p.Gly43= p.G43= ENST00000349064 NM_004769.3 43 ggG/ggA 0 +ACCN5 UCSF GRCh37 4 156757966 156757966 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 74 157 0 ENST00000537611.2:c.1110C>T p.Asn370= p.N370= ENST00000537611 NM_017419.2 370 aaC/aaT 0 +ACCSL UCSF GRCh37 11 44077841 44077841 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 1 42 80 0 ENST00000378832.1:c.1292C>T p.Thr431Ile p.T431I ENST00000378832 NM_001031854.2 431 aCc/aTc 0 +ACHE UCSF GRCh37 7 100490847 100490847 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 34 55 0 ENST00000241069.5:c.1007G>A p.Gly336Glu p.G336E ENST00000241069 NM_000665.3 336 gGa/gAa 0 +ACOT11 UCSF GRCh37 1 55073742 55073742 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 31 55 0 ENST00000371316.3:c.1629+1G>A p.X543_splice ENST00000371316 NM_015547.3 0 +ACOT11 UCSF GRCh37 1 55065014 55065014 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 25 113 0 ENST00000371316.3:c.810C>T p.Phe270= p.F270= ENST00000371316 NM_015547.3 270 ttC/ttT 0 +ACOXL UCSF GRCh37 2 111542360 111542360 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 51 104 0 ENST00000389811.4:c.127C>T p.Leu43Phe p.L43F ENST00000389811 43 Ctc/Ttc 0 +ACPT UCSF GRCh37 19 51297182 51297182 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 74 177 0 ENST00000270593.1:c.816G>A p.Arg272= p.R272= ENST00000270593 NM_033068.2 272 cgG/cgA 0 +ACSL4 UCSF GRCh37 X 108924505 108924505 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 74 174 0 ENST00000340800.2:c.629G>A p.Ser210Asn p.S210N ENST00000340800 NM_022977.2 210 aGt/aAt 0 +ACSL6 UCSF GRCh37 5 131309079 131309079 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 50 100 0 ENST00000379240.1:c.1008C>T p.Cys336= p.C336= ENST00000379240 336 tgC/tgT 0 +ACSM1 UCSF GRCh37 16 20702440 20702440 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 77 190 0 ENST00000307493.4:c.71C>T p.Pro24Leu p.P24L ENST00000307493 NM_052956.2 24 cCt/cTt 0 +ACSM1 UCSF GRCh37 16 20681275 20681275 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 53 103 0 ENST00000307493.4:c.786C>T p.Val262= p.V262= ENST00000307493 NM_052956.2 262 gtC/gtT 0 +ACSM5 UCSF GRCh37 16 20430602 20430602 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 56 108 0 ENST00000331849.4:c.468C>T p.Tyr156= p.Y156= ENST00000331849 NM_017888.2 156 taC/taT 0 +ACTL7B UCSF GRCh37 9 111617245 111617245 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 55 98 1 ENST00000374667.3:c.966C>T p.Cys322= p.C322= ENST00000374667 NM_006686.3 322 tgC/tgT 0 +ACTR1B UCSF GRCh37 2 98275057 98275057 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 49 121 0 ENST00000289228.5:c.490G>A p.Val164Ile p.V164I ENST00000289228 NM_005735.3 164 Gtc/Atc 0 +ACTRT2 UCSF GRCh37 1 2938970 2938970 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 49 111 0 ENST00000378404.2:c.720G>A p.Arg240= p.R240= ENST00000378404 NM_080431.4 240 agG/agA 0 +ACVR1C UCSF GRCh37 2 158443801 158443801 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 105 253 0 ENST00000243349.8:c.202G>A p.Glu68Lys p.E68K ENST00000243349 NM_001111032.1 68 Gaa/Aaa 0 +ADAD2 UCSF GRCh37 16 84230287 84230287 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 67 106 0 ENST00000315906.5:c.1561G>A p.Ala521Thr p.A521T ENST00000315906 NM_001145400.1 521 Gcc/Acc 0 +ADAM11 UCSF GRCh37 17 42855391 42855391 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 65 147 0 ENST00000200557.6:c.2142C>T p.Pro714= p.P714= ENST00000200557 NM_002390.4 714 ccC/ccT 0 +ADAM19 UCSF GRCh37 5 156915317 156915317 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 77 153 0 ENST00000517905.1:c.2506C>T p.Pro836Ser p.P836S ENST00000517905 836 Cca/Tca 0 +ADAM19 UCSF GRCh37 5 156915418 156915418 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 43 104 0 ENST00000517905.1:c.2405C>T p.Ser802Phe p.S802F ENST00000517905 802 tCc/tTc 0 +ADAM23 UCSF GRCh37 2 207310049 207310049 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 61 138 0 ENST00000264377.3:c.233C>T p.Thr78Ile p.T78I ENST00000264377 NM_003812.3 78 aCt/aTt 0 +ADAMTS14 UCSF GRCh37 10 72498678 72498678 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 27 62 0 ENST00000373207.1:c.1680G>A p.Lys560= p.K560= ENST00000373207 NM_080722.3 560 aaG/aaA 0 +ADAMTS16 UCSF GRCh37 5 5319220 5319220 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 37 83 0 ENST00000274181.7:c.3644G>A p.Cys1215Tyr p.C1215Y ENST00000274181 NM_139056.2 1215 tGc/tAc 0 +ADAMTS2 UCSF GRCh37 5 178699957 178699957 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 27 86 0 ENST00000251582.7:c.643C>T p.Pro215Ser p.P215S ENST00000251582 NM_014244.4 215 Cca/Tca 0 +ADAMTS5 UCSF GRCh37 21 28327088 28327088 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 48 127 0 ENST00000284987.5:c.1207C>T p.His403Tyr p.H403Y ENST00000284987 NM_007038.3 403 Cac/Tac 0 +ADAMTS7 UCSF GRCh37 15 79051788 79051788 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 8 19 0 ENST00000388820.4:c.5036G>A p.Gly1679Asp p.G1679D ENST00000388820 NM_014272.3 1679 gGc/gAc 0 +ADAMTS8 UCSF GRCh37 11 130275496 130275496 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 52 98 0 ENST00000257359.6:c.2627C>T p.Pro876Leu p.P876L ENST00000257359 NM_007037.4 876 cCc/cTc 0 +ADCK4 UCSF GRCh37 19 41208533 41208533 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 53 92 0 ENST00000324464.3:c.865C>T p.Arg289Cys p.R289C ENST00000324464 NM_024876.3 289 Cgt/Tgt 0 +ADCK5 UCSF GRCh37 8 145616355 145616355 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 145 40 83 0 ENST00000308860.6:c.565G>A p.Asp189Asn p.D189N ENST00000308860 NM_174922.4 189 Gac/Aac 0 +ADCY4 UCSF GRCh37 14 24798336 24798336 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 37 78 0 ENST00000310677.4:c.1455G>A p.Trp485Ter p.W485* ENST00000310677 NM_001198568.1 485 tgG/tgA 0 +ADCY5 UCSF GRCh37 3 123049809 123049809 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 35 97 0 ENST00000462833.1:c.1573G>A p.Gly525Arg p.G525R ENST00000462833 NM_183357.2 525 Ggg/Agg 0 +ADCY8 UCSF GRCh37 8 131922112 131922112 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 285 73 128 0 ENST00000286355.5:c.1482G>A p.Arg494= p.R494= ENST00000286355 NM_001115.2 494 agG/agA 0 +ADIPOR2 UCSF GRCh37 12 1895171 1895171 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 83 177 0 ENST00000357103.4:c.1094G>A p.Gly365Asp p.G365D ENST00000357103 NM_024551.2 365 gGt/gAt 0 +ADNP UCSF GRCh37 20 49508225 49508225 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 134 118 181 0 ENST00000349014.3:c.3026G>A p.Ser1009Asn p.S1009N ENST00000349014 NM_001282532.1 1009 aGt/aAt 0 +ADNP2 UCSF GRCh37 18 77893588 77893588 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 67 177 0 ENST00000262198.4:c.292G>A p.Asp98Asn p.D98N ENST00000262198 NM_014913.3 98 Gat/Aat 0 +ADPRHL2 UCSF GRCh37 1 36557297 36557297 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 64 156 0 ENST00000373178.4:c.387C>T p.Asn129= p.N129= ENST00000373178 NM_017825.2 129 aaC/aaT 0 +AFAP1 UCSF GRCh37 4 7870389 7870389 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 19 55 0 ENST00000358461.2:c.185C>T p.Pro62Leu p.P62L ENST00000358461 NM_198595.2 62 cCt/cTt 0 +AFAP1 UCSF GRCh37 4 7774726 7774726 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 23 46 0 ENST00000358461.2:c.1822C>T p.Gln608Ter p.Q608* ENST00000358461 NM_198595.2 608 Cag/Tag 0 +AFG3L2 UCSF GRCh37 18 12363780 12363780 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 57 128 0 ENST00000269143.3:c.627+1G>A p.X209_splice ENST00000269143 NM_006796.2 0 +AFM UCSF GRCh37 4 74347532 74347533 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 0 ENST00000226355.3:c.47dup p.Leu16PhefsTer3 p.L16Ffs*3 ENST00000226355 NM_001133.2 14 ttt/tTtt 0 +AGAP1 UCSF GRCh37 2 236817473 236817473 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 81 178 0 ENST00000304032.8:c.1247C>T p.Ala416Val p.A416V ENST00000304032 NM_001037131.2 416 gCc/gTc 0 +AGAP2 UCSF GRCh37 12 58126730 58126730 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 108 211 0 ENST00000547588.1:c.1582G>A p.Gly528Arg p.G528R ENST00000547588 NM_001122772.2 528 Gga/Aga 0 +AGBL4 UCSF GRCh37 1 50163095 50163095 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 71 192 0 ENST00000371839.1:c.172G>A p.Val58Met p.V58M ENST00000371839 NM_032785.3 58 Gtg/Atg 0 +AGGF1 UCSF GRCh37 5 76355552 76355552 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 55 150 0 ENST00000312916.7:c.1828C>T p.Pro610Ser p.P610S ENST00000312916 NM_018046.4 610 Cct/Tct 0 +AGPAT9 UCSF GRCh37 4 84516040 84516040 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 120 112 221 0 ENST00000264409.4:c.781G>A p.Ala261Thr p.A261T ENST00000264409 NM_032717.4 261 Gct/Act 0 +AGPAT9 UCSF GRCh37 4 84519800 84519800 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 27 86 0 ENST00000264409.4:c.1129G>A p.Gly377Arg p.G377R ENST00000264409 NM_032717.4 377 Gga/Aga 0 +AGRN UCSF GRCh37 1 978819 978819 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 11 36 0 ENST00000379370.2:c.1585G>A p.Ala529Thr p.A529T ENST00000379370 NM_198576.3 529 Gcg/Acg 0 +AHI1 UCSF GRCh37 6 135787148 135787148 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 152 126 222 0 ENST00000265602.6:c.553G>A p.Asp185Asn p.D185N ENST00000265602 NM_001134831.1 185 Gat/Aat 0 +AHNAK UCSF GRCh37 11 62288699 62288699 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 122 125 263 0 ENST00000378024.4:c.13190C>T p.Pro4397Leu p.P4397L ENST00000378024 NM_001620.2 4397 cCc/cTc 0 +AHNAK UCSF GRCh37 11 62288419 62288419 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 119 93 180 1 ENST00000378024.4:c.13470G>A p.Gly4490= p.G4490= ENST00000378024 NM_001620.2 4490 ggG/ggA 0 +AHNAK UCSF GRCh37 11 62297032 62297032 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 116 224 0 ENST00000378024.4:c.4857G>A p.Lys1619= p.K1619= ENST00000378024 NM_001620.2 1619 aaG/aaA 0 +AHNAK UCSF GRCh37 11 62287342 62287342 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 79 190 0 ENST00000378024.4:c.14547C>T p.Ile4849= p.I4849= ENST00000378024 NM_001620.2 4849 atC/atT 0 +AHNAK2 UCSF GRCh37 14 105423788 105423788 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 17 35 0 ENST00000333244.5:c.172G>A p.Val58Ile p.V58I ENST00000333244 NM_138420.2 58 Gtc/Atc 0 +AHRR UCSF GRCh37 5 422934 422934 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 33 73 0 ENST00000505113.1:c.544C>T p.Pro182Ser p.P182S ENST00000505113 NM_001242412.1 182 Ccc/Tcc 0 +AICDA UCSF GRCh37 12 8758005 8758005 + missense_variant Missense_Mutation SNP A A T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 47 104 0 ENST00000229335.6:c.233T>A p.Val78Asp p.V78D ENST00000229335 NM_020661.2 78 gTc/gAc 0 +AIPL1 UCSF GRCh37 17 6329013 6329013 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 39 51 0 ENST00000381129.3:c.922C>T p.Leu308= p.L308= ENST00000381129 NM_014336.3 308 Ctg/Ttg 0 +AIRE UCSF GRCh37 21 45713770 45713770 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 9 23 0 ENST00000291582.5:c.1377C>T p.Phe459= p.F459= ENST00000291582 NM_000383.3 459 ttC/ttT 0 +AK8 UCSF GRCh37 9 135698602 135698602 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 160 79 156 0 ENST00000298545.3:c.879G>A p.Arg293= p.R293= ENST00000298545 NM_152572.2 293 agG/agA 0 +AKAP10 UCSF GRCh37 17 19823376 19823376 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 39 99 0 ENST00000225737.6:c.1807C>T p.Pro603Ser p.P603S ENST00000225737 NM_007202.3 603 Cct/Tct 0 +AKAP12 UCSF GRCh37 6 151673720 151673720 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 73 147 0 ENST00000253332.1:c.4194C>T p.Pro1398= p.P1398= ENST00000253332 1398 ccC/ccT 0 +AKAP12 UCSF GRCh37 6 151674666 151674666 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 90 166 0 ENST00000253332.1:c.5140C>T p.Leu1714= p.L1714= ENST00000253332 1714 Ctg/Ttg 0 +AKAP4 UCSF GRCh37 X 49957587 49957587 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 80 179 0 ENST00000358526.2:c.1777G>A p.Ala593Thr p.A593T ENST00000358526 NM_003886.2 593 Gcc/Acc 0 +AKAP8L UCSF GRCh37 19 15512078 15512078 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 74 119 0 ENST00000397410.5:c.699C>T p.Phe233= p.F233= ENST00000397410 NM_014371.2 233 ttC/ttT 0 +AKAP9 UCSF GRCh37 7 91622205 91622205 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 49 109 0 ENST00000356239.3:c.412G>A p.Glu138Lys p.E138K ENST00000356239 NM_147185.2 138 Gaa/Aaa 0 +AKNA UCSF GRCh37 9 117124707 117124707 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 16 43 0 ENST00000307564.4:c.1895C>T p.Pro632Leu p.P632L ENST00000307564 NM_030767.4 632 cCt/cTt 0 +AKR1B1 UCSF GRCh37 7 134136450 134136450 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 50 99 0 ENST00000285930.4:c.122G>A p.Arg41His p.R41H ENST00000285930 NM_001628.2 41 cGc/cAc 0 +AKR1C1 UCSF GRCh37 10 5011051 5011051 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 170 67 159 0 ENST00000380872.4:c.485C>T p.Ser162Phe p.S162F ENST00000380872 NM_001353.5 162 tCc/tTc 0 +ALAD UCSF GRCh37 9 116154398 116154398 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 16 41 0 ENST00000409155.3:c.164+1G>A p.X55_splice ENST00000409155 NM_000031.5 0 +ALDH3B2 UCSF GRCh37 11 67432886 67432886 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 28 159 0 ENST00000349015.3:c.576C>T p.Gly192= p.G192= ENST00000349015 NM_000695.3 192 ggC/ggT 0 +ALDH9A1 UCSF GRCh37 1 165636589 165636589 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 43 135 0 ENST00000354775.4:c.1306G>A p.Ala436Thr p.A436T ENST00000354775 NM_000696.3 436 Gcc/Acc 0 +ALG10 UCSF GRCh37 12 34179346 34179346 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 136 132 266 0 ENST00000266483.2:c.918C>T p.Leu306= p.L306= ENST00000266483 NM_032834.3 306 ctC/ctT 0 +ALKBH4 UCSF GRCh37 7 102098081 102098081 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 16 14 0 ENST00000292566.3:c.669G>A p.Arg223= p.R223= ENST00000292566 NM_017621.3 223 cgG/cgA 0 +ALMS1 UCSF GRCh37 2 73675671 73675671 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 103 194 0 ENST00000264448.6:c.2014G>A p.Glu672Lys p.E672K ENST00000264448 NM_015120.4 672 Gag/Aag 0 +ALOX15 UCSF GRCh37 17 4542415 4542415 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 74 151 0 ENST00000293761.3:c.350G>A p.Gly117Asp p.G117D ENST00000293761 NM_001140.3 117 gGc/gAc 0 +ALOX5AP UCSF GRCh37 13 31338144 31338144 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 88 196 0 ENST00000380490.3:c.387C>T p.Gly129= p.G129= ENST00000380490 NM_001629.3 129 ggC/ggT 0 +ALPK2 UCSF GRCh37 18 56202444 56202444 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 90 196 0 ENST00000361673.3:c.4975G>A p.Glu1659Lys p.E1659K ENST00000361673 NM_052947.3 1659 Gaa/Aaa 0 +ALPK2 UCSF GRCh37 18 56246635 56246635 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 92 188 0 ENST00000361673.3:c.1373C>T p.Ala458Val p.A458V ENST00000361673 NM_052947.3 458 gCt/gTt 0 +ALPK3 UCSF GRCh37 15 85383430 85383430 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 38 108 0 ENST00000258888.5:c.1526C>T p.Ala509Val p.A509V ENST00000258888 NM_020778.4 509 gCc/gTc 0 +ALPK3 UCSF GRCh37 15 85403012 85403012 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 34 42 0 ENST00000258888.5:c.4577G>A p.Gly1526Glu p.G1526E ENST00000258888 NM_020778.4 1526 gGg/gAg 0 +ALPP UCSF GRCh37 2 233245969 233245969 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 23 73 0 ENST00000392027.2:c.1201C>T p.Pro401Ser p.P401S ENST00000392027 NM_001632.3 401 Cct/Tct 0 +ALS2CL UCSF GRCh37 3 46724728 46724728 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 1 21 40 0 ENST00000318962.4:c.1001C>T p.Pro334Leu p.P334L ENST00000318962 NM_147129.3 334 cCc/cTc 0 +AMBN UCSF GRCh37 4 71467161 71467161 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 113 197 0 ENST00000322937.6:c.321C>T p.Pro107= p.P107= ENST00000322937 NM_016519.5 107 ccC/ccT 0 +AMBRA1 UCSF GRCh37 11 46563580 46563580 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 82 133 0 ENST00000458649.2:c.1987C>T p.Gln663Ter p.Q663* ENST00000458649 663 Cag/Tag 0 +AMMECR1L UCSF GRCh37 2 128628503 128628503 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 86 81 156 0 ENST00000272647.5:c.519-1G>A p.X173_splice ENST00000272647 NM_001199140.1 0 +AMOT UCSF GRCh37 X 112058905 112058905 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 23 26 0 ENST00000371959.3:c.1073C>T p.Pro358Leu p.P358L ENST00000371959 NM_001113490.1 358 cCt/cTt 0 +AMOT UCSF GRCh37 X 112065626 112065626 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 21 42 0 ENST00000371959.3:c.729C>T p.Pro243= p.P243= ENST00000371959 NM_001113490.1 243 ccC/ccT 0 +ANGEL1 UCSF GRCh37 14 77273075 77273075 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 105 179 0 ENST00000251089.2:c.1064G>A p.Gly355Asp p.G355D ENST00000251089 NM_015305.3 355 gGc/gAc 0 +ANGPTL6 UCSF GRCh37 19 10205520 10205520 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 48 82 0 ENST00000253109.4:c.677C>T p.Pro226Leu p.P226L ENST00000253109 NM_031917.2 226 cCc/cTc 0 +ANGPTL6 UCSF GRCh37 19 10204462 10204462 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 74 168 0 ENST00000253109.4:c.858G>A p.Trp286Ter p.W286* ENST00000253109 NM_031917.2 286 tgG/tgA 0 +ANGPTL6 UCSF GRCh37 19 10205450 10205450 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 76 150 1 ENST00000253109.4:c.747C>T p.Val249= p.V249= ENST00000253109 NM_031917.2 249 gtC/gtT 0 +ANK2 UCSF GRCh37 4 114257791 114257791 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 56 135 0 ENST00000357077.4:c.3650G>A p.Ser1217Asn p.S1217N ENST00000357077 NM_001148.4 1217 aGc/aAc 0 +ANK3 UCSF GRCh37 10 61834433 61834433 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 83 60 184 0 ENST00000280772.2:c.6206A>G p.Lys2069Arg p.K2069R ENST00000280772 NM_020987.3 2069 aAa/aGa 0 +ANKDD1A UCSF GRCh37 15 65214219 65214219 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 27 65 0 ENST00000319580.8:c.*7+1G>A p.X3_splice ENST00000319580 0 +ANKHD1 UCSF GRCh37 5 139864786 139864786 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 47 99 0 ENST00000360839.2:c.1951G>A p.Val651Ile p.V651I ENST00000360839 NM_017747.2 651 Gtt/Att 0 +ANKHD1 UCSF GRCh37 5 139887397 139887397 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 55 140 0 ENST00000360839.2:c.3579C>T p.Pro1193= p.P1193= ENST00000360839 NM_017747.2 1193 ccC/ccT 0 +ANKLE2 UCSF GRCh37 12 133311100 133311100 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 94 198 0 ENST00000357997.5:c.1762G>A p.Val588Ile p.V588I ENST00000357997 NM_015114.1 588 Gtt/Att 0 +ANKLE2 UCSF GRCh37 12 133313506 133313506 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 69 106 0 ENST00000357997.5:c.1566C>T p.Ala522= p.A522= ENST00000357997 NM_015114.1 522 gcC/gcT 0 +ANKMY2 UCSF GRCh37 7 16655440 16655440 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 37 137 0 ENST00000306999.2:c.460C>T p.Pro154Ser p.P154S ENST00000306999 NM_020319.2 154 Cca/Tca 0 +ANKRD13B UCSF GRCh37 17 27936181 27936181 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 29 43 0 ENST00000394859.3:c.643G>A p.Asp215Asn p.D215N ENST00000394859 NM_152345.4 215 Gac/Aac 0 +ANKRD17 UCSF GRCh37 4 73956561 73956561 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 117 241 0 ENST00000358602.4:c.6784C>T p.Pro2262Ser p.P2262S ENST00000358602 NM_032217.3 2262 Cct/Tct 0 +ANKRD17 UCSF GRCh37 4 73964177 73964177 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 49 140 0 ENST00000358602.4:c.4634C>T p.Ser1545Phe p.S1545F ENST00000358602 NM_032217.3 1545 tCt/tTt 0 +ANKRD2 UCSF GRCh37 10 99338294 99338294 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 11 16 0 ENST00000307518.5:c.469G>A p.Val157Met p.V157M ENST00000307518 157 Gtg/Atg 0 +ANKRD20A1 UCSF GRCh37 9 67951934 67951934 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 37 211 0 ENST00000377477.2:c.897G>A p.Gln299= p.Q299= ENST00000377477 NM_032250.3 299 caG/caA 0 +ANKRD56 UCSF GRCh37 4 77817460 77817460 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 52 113 0 ENST00000334306.2:c.1543C>T p.Leu515Phe p.L515F ENST00000334306 NM_001029870.1 515 Ctc/Ttc 0 +ANKS6 UCSF GRCh37 9 101552469 101552469 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 100 51 114 0 ENST00000353234.4:c.779C>T p.Thr260Ile p.T260I ENST00000353234 260 aCc/aTc 0 +ANO10 UCSF GRCh37 3 43618310 43618310 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 51 130 0 ENST00000292246.3:c.1036C>T p.Leu346= p.L346= ENST00000292246 NM_018075.3 346 Cta/Tta 0 +ANO2 UCSF GRCh37 12 5939622 5939622 + synonymous_variant Silent SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 55 47 124 0 ENST00000356134.5:c.810T>C p.Asp270= p.D270= ENST00000356134 270 gaT/gaC 0 +ANO3 UCSF GRCh37 11 26569093 26569093 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 88 200 0 ENST00000256737.3:c.1285G>A p.Val429Ile p.V429I ENST00000256737 NM_031418.2 429 Gta/Ata 0 +ANXA11 UCSF GRCh37 10 81929013 81929013 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 16 24 0 ENST00000372231.3:c.273G>A p.Gly91= p.G91= ENST00000372231 91 ggG/ggA 0 +AOX1 UCSF GRCh37 2 201515866 201515866 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 71 157 0 ENST00000374700.2:c.3017G>A p.Gly1006Glu p.G1006E ENST00000374700 NM_001159.3 1006 gGa/gAa 0 +AP2A1 UCSF GRCh37 19 50302723 50302723 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 36 75 0 ENST00000359032.5:c.1105C>T p.His369Tyr p.H369Y ENST00000359032 NM_014203.2 369 Cac/Tac 0 +AP3D1 UCSF GRCh37 19 2137026 2137026 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 8 18 0 ENST00000345016.5:c.338C>T p.Thr113Ile p.T113I ENST00000345016 NM_003938.6 113 aCc/aTc 0 +APBB1IP UCSF GRCh37 10 26849663 26849663 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 180 84 156 0 ENST00000376236.4:c.1259G>A p.Gly420Glu p.G420E ENST00000376236 NM_019043.3 420 gGg/gAg 0 +APC UCSF GRCh37 5 112177281 112177281 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 77 82 154 0 ENST00000257430.4:c.5990G>A p.Gly1997Glu p.G1997E ENST00000257430 NM_000038.5 1997 gGa/gAa 0 +APC2 UCSF GRCh37 19 1455233 1455233 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 11 21 0 ENST00000233607.2:c.499G>A p.Asp167Asn p.D167N ENST00000233607 NM_005883.2 167 Gac/Aac 0 +APC2 UCSF GRCh37 19 1466048 1466048 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 13 13 0 ENST00000233607.2:c.2748G>A p.Lys916= p.K916= ENST00000233607 NM_005883.2 916 aaG/aaA 0 +APCDD1L UCSF GRCh37 20 57036226 57036226 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 45 71 0 ENST00000371149.3:c.1126C>T p.Pro376Ser p.P376S ENST00000371149 NM_153360.1 376 Cca/Tca 0 +API5 UCSF GRCh37 11 43350277 43350277 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 61 123 0 ENST00000531273.1:c.961C>T p.Pro321Ser p.P321S ENST00000531273 321 Cct/Tct 0 +APLP1 UCSF GRCh37 19 36365772 36365772 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 28 35 0 ENST00000221891.4:c.1344+1G>A p.X448_splice ENST00000221891 NM_001024807.1 0 +APOA1 UCSF GRCh37 11 116707873 116707873 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 40 90 0 ENST00000236850.4:c.44G>A p.Gly15Glu p.G15E ENST00000236850 NM_000039.1 15 gGg/gAg 0 +APOB UCSF GRCh37 2 21227277 21227277 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 60 145 0 ENST00000233242.1:c.11951C>T p.Thr3984Ile p.T3984I ENST00000233242 NM_000384.2 3984 aCc/aTc 0 +APOB UCSF GRCh37 2 21232067 21232067 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 105 175 0 ENST00000233242.1:c.7673C>T p.Ala2558Val p.A2558V ENST00000233242 NM_000384.2 2558 gCt/gTt 0 +APOB UCSF GRCh37 2 21232078 21232078 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 69 146 0 ENST00000233242.1:c.7662G>A p.Trp2554Ter p.W2554* ENST00000233242 NM_000384.2 2554 tgG/tgA 0 +APP UCSF GRCh37 21 27284207 27284207 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 53 121 0 ENST00000346798.3:c.1755G>A p.Arg585= p.R585= ENST00000346798 NM_000484.3 585 agG/agA 0 +AQP1 UCSF GRCh37 7 30963178 30963178 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 18 20 49 0 ENST00000311813.4:c.744C>T p.Gly248= p.G248= ENST00000311813 NM_198098.2 248 ggC/ggT 0 +AQP5 UCSF GRCh37 12 50358930 50358930 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 31 50 0 ENST00000293599.6:c.768G>A p.Arg256= p.R256= ENST00000293599 NM_001651.3 256 cgG/cgA 0 +AR UCSF GRCh37 X 66765407 66765407 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 6 14 0 ENST00000374690.3:c.419C>T p.Ala140Val p.A140V ENST00000374690 NM_000044.3 140 gCc/gTc 0 +AR UCSF GRCh37 X 66766136 66766136 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 13 30 0 ENST00000374690.3:c.1148C>T p.Pro383Leu p.P383L ENST00000374690 NM_000044.3 383 cCc/cTc 0 +ARAP2 UCSF GRCh37 4 36115845 36115845 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 124 112 201 0 ENST00000303965.4:c.4103C>T p.Pro1368Leu p.P1368L ENST00000303965 NM_015230.3 1368 cCt/cTt 0 +ARAP2 UCSF GRCh37 4 36212084 36212084 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 68 138 1 ENST00000303965.4:c.1415C>T p.Pro472Leu p.P472L ENST00000303965 NM_015230.3 472 cCc/cTc 0 +ARAP2 UCSF GRCh37 4 36109269 36109269 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 59 179 0 ENST00000303965.4:c.4203G>A p.Arg1401= p.R1401= ENST00000303965 NM_015230.3 1401 cgG/cgA 0 +ARAP3 UCSF GRCh37 5 141033734 141033734 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 40 104 0 ENST00000239440.4:c.4418G>A p.Ser1473Asn p.S1473N ENST00000239440 NM_022481.5 1473 aGc/aAc 0 +ARC UCSF GRCh37 8 143695255 143695255 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 7 25 0 ENST00000356613.2:c.378G>A p.Trp126Ter p.W126* ENST00000356613 NM_015193.4 126 tgG/tgA 0 +ARCN1 UCSF GRCh37 11 118454053 118454053 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 55 125 0 ENST00000264028.4:c.427G>A p.Val143Met p.V143M ENST00000264028 NM_001655.4 143 Gtg/Atg 0 +ARFGEF2 UCSF GRCh37 20 47582530 47582530 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 63 139 0 ENST00000371917.4:c.1029C>T p.Asp343= p.D343= ENST00000371917 NM_006420.2 343 gaC/gaT 0 +ARGLU1 UCSF GRCh37 13 107196384 107196384 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 56 72 0 ENST00000400198.3:c.782C>T p.Ser261Phe p.S261F ENST00000400198 NM_018011.3 261 tCc/tTc 0 +ARHGAP15 UCSF GRCh37 2 144193197 144193197 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 21 59 0 ENST00000295095.6:c.502C>T p.Leu168Phe p.L168F ENST00000295095 NM_018460.3 168 Ctt/Ttt 0 +ARHGAP22 UCSF GRCh37 10 49687707 49687707 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 25 34 0 ENST00000249601.4:c.423C>T p.Arg141= p.R141= ENST00000249601 NM_021226.3 141 cgC/cgT 0 +ARHGAP23 UCSF GRCh37 17 36623249 36623249 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 17 0 ENST00000431231.2:c.1325C>T p.Pro442Leu p.P442L ENST00000431231 NM_001199417.1 442 cCc/cTc 0 +ARHGAP31 UCSF GRCh37 3 119120774 119120774 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 47 99 0 ENST00000264245.4:c.1175C>T p.Thr392Ile p.T392I ENST00000264245 NM_020754.2 392 aCc/aTc 0 +ARHGAP33 UCSF GRCh37 19 36278595 36278595 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 40 68 0 ENST00000314737.5:c.2645C>T p.Pro882Leu p.P882L ENST00000314737 NM_052948.3 882 cCc/cTc 0 +ARHGAP9 UCSF GRCh37 12 57868745 57868745 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 30 80 0 ENST00000393791.3:c.1564G>A p.Gly522Ser p.G522S ENST00000393791 NM_032496.2 522 Ggc/Agc 0 +ARHGEF1 UCSF GRCh37 19 42392174 42392174 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 30 68 0 ENST00000354532.3:c.21G>A p.Gly7= p.G7= ENST00000354532 NM_004706.3 7 ggG/ggA 0 +ARHGEF10 UCSF GRCh37 8 1893800 1893800 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 46 118 0 ENST00000398564.1:c.3451C>T p.Pro1151Ser p.P1151S ENST00000398564 1151 Cct/Tct 0 +ARHGEF12 UCSF GRCh37 11 120345319 120345319 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 64 149 0 ENST00000397843.2:c.3084G>A p.Trp1028Ter p.W1028* ENST00000397843 NM_015313.2 1028 tgG/tgA 0 +ARHGEF16 UCSF GRCh37 1 3396387 3396387 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 28 68 0 ENST00000378378.4:c.1900G>A p.Val634Met p.V634M ENST00000378378 NM_014448.3 634 Gtg/Atg 0 +ARHGEF17 UCSF GRCh37 11 73073499 73073499 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 12 29 0 ENST00000263674.3:c.4716G>A p.Arg1572= p.R1572= ENST00000263674 NM_014786.3 1572 agG/agA 0 +ARHGEF18 UCSF GRCh37 19 7518385 7518385 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 71 172 0 ENST00000359920.6:c.1324G>A p.Ala442Thr p.A442T ENST00000359920 NM_001130955.1 442 Gcc/Acc 0 +ARHGEF37 UCSF GRCh37 5 149001611 149001611 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 16 42 0 ENST00000333677.6:c.1321G>A p.Gly441Arg p.G441R ENST00000333677 NM_001001669.2 441 Gga/Aga 0 +ARHGEF40 UCSF GRCh37 14 21542423 21542423 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 44 97 0 ENST00000298694.4:c.534G>A p.Trp178Ter p.W178* ENST00000298694 NM_001278529.1 178 tgG/tgA 0 +ARHGEF9 UCSF GRCh37 X 62858032 62858032 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 19 17 49 0 ENST00000253401.6:c.1427A>G p.Asn476Ser p.N476S ENST00000253401 NM_015185.2 476 aAc/aGc 0 +ARID1A UCSF GRCh37 1 27087438 27087438 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 90 85 168 0 ENST00000324856.7:c.2012G>A p.Gly671Glu p.G671E ENST00000324856 NM_006015.4 671 gGa/gAa 0 +ARID1A UCSF GRCh37 1 27106776 27106776 + synonymous_variant Silent SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 108 97 196 0 ENST00000324856.7:c.6387C>T p.Asp2129= p.D2129= ENST00000324856 NM_006015.4 2129 gaC/gaT 0 +ARID1B UCSF GRCh37 6 157405897 157405897 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 64 163 0 ENST00000350026.5:c.2100C>T p.Ser700= p.S700= ENST00000350026 NM_017519.2 700 agC/agT 0 +ARID2 UCSF GRCh37 12 46125022 46125022 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 59 140 0 ENST00000334344.6:c.209G>A p.Gly70Glu p.G70E ENST00000334344 NM_152641.2 70 gGa/gAa 0 +ARID3C UCSF GRCh37 9 34621480 34621480 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 20 40 0 ENST00000378909.2:c.1214G>A p.Gly405Glu p.G405E ENST00000378909 NM_001017363.1 405 gGg/gAg 0 +ARID4B UCSF GRCh37 1 235383229 235383229 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 49 140 0 ENST00000264183.3:c.1462G>A p.Glu488Lys p.E488K ENST00000264183 NM_016374.5 488 Gaa/Aaa 0 +ARID5B UCSF GRCh37 10 63852245 63852245 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 74 134 0 ENST00000279873.7:c.3023C>T p.Ala1008Val p.A1008V ENST00000279873 NM_032199.2 1008 gCg/gTg 0 +ARL4A UCSF GRCh37 7 12728445 12728445 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 152 119 240 0 ENST00000356797.3:c.566G>A p.Arg189Lys p.R189K ENST00000356797 189 aGa/aAa 0 +ARL8B UCSF GRCh37 3 5216037 5216037 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 70 134 0 ENST00000256496.3:c.449C>T p.Ser150Phe p.S150F ENST00000256496 NM_018184.2 150 tCt/tTt 0 +ARMC2 UCSF GRCh37 6 109225435 109225435 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 128 105 220 0 ENST00000392644.4:c.850G>A p.Glu284Lys p.E284K ENST00000392644 NM_032131.4 284 Gaa/Aaa 0 +ARMC4 UCSF GRCh37 10 28272880 28272880 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 130 56 143 0 ENST00000305242.5:c.711C>T p.Ala237= p.A237= ENST00000305242 NM_018076.2 237 gcC/gcT 0 +ARMC5 UCSF GRCh37 16 31473836 31473836 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 37 52 0 ENST00000268314.4:c.968G>A p.Gly323Asp p.G323D ENST00000268314 NM_001105247.1 323 gGc/gAc 0 +ARMCX5 UCSF GRCh37 X 101857164 101857164 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 65 160 0 ENST00000246174.2:c.95G>A p.Gly32Asp p.G32D ENST00000246174 NM_001168480.1 32 gGt/gAt 0 +ARNT2 UCSF GRCh37 15 80869262 80869262 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 77 182 0 ENST00000303329.4:c.1569C>T p.Ser523= p.S523= ENST00000303329 NM_014862.3 523 tcC/tcT 0 +ARPM1 UCSF GRCh37 3 169485867 169485867 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 54 129 0 ENST00000330368.2:c.472G>A p.Val158Ile p.V158I ENST00000330368 NM_032487.4 158 Gtt/Att 0 +ARRDC1 UCSF GRCh37 9 140508117 140508117 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 129 55 117 0 ENST00000371421.4:c.331G>A p.Val111Met p.V111M ENST00000371421 NM_152285.2 111 Gtg/Atg 0 +ARSA UCSF GRCh37 22 51065061 51065061 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 39 76 0 ENST00000216124.5:c.812G>A p.Gly271Glu p.G271E ENST00000216124 NM_000487.5 271 gGg/gAg 0 +ARSF UCSF GRCh37 X 3030361 3030361 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 84 218 0 ENST00000359361.2:c.1537C>T p.Pro513Ser p.P513S ENST00000359361 NM_004042.4 513 Ccc/Tcc 0 +ARSJ UCSF GRCh37 4 114824812 114824812 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 72 159 1 ENST00000315366.7:c.418C>T p.Leu140Phe p.L140F ENST00000315366 NM_024590.3 140 Ctt/Ttt 0 +ART3 UCSF GRCh37 4 77003181 77003181 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 75 180 0 ENST00000355810.4:c.274G>A p.Asp92Asn p.D92N ENST00000355810 NM_001130016.2 92 Gat/Aat 0 +ART4 UCSF GRCh37 12 14982321 14982321 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 44 120 1 ENST00000228936.4:c.929C>T p.Ser310Phe p.S310F ENST00000228936 NM_021071.2 310 tCc/tTc 0 +ASB1 UCSF GRCh37 2 239344428 239344428 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 38 59 0 ENST00000264607.4:c.268C>T p.His90Tyr p.H90Y ENST00000264607 NM_001040445.1 90 Cat/Tat 0 +ASF1B UCSF GRCh37 19 14231375 14231375 + missense_variant Missense_Mutation SNP A A T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 18 31 0 ENST00000263382.3:c.505T>A p.Ser169Thr p.S169T ENST00000263382 NM_018154.2 169 Tcc/Acc 0 +ASH1L UCSF GRCh37 1 155451034 155451034 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 61 167 0 ENST00000368346.3:c.1627G>A p.Ala543Thr p.A543T ENST00000368346 543 Gct/Act 0 +ASH1L UCSF GRCh37 1 155449132 155449132 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 75 159 0 ENST00000368346.3:c.3529C>T p.Leu1177Phe p.L1177F ENST00000368346 1177 Ctc/Ttc 0 +ASL UCSF GRCh37 7 65551635 65551635 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 16 42 0 ENST00000304874.9:c.510C>T p.Ser170= p.S170= ENST00000304874 NM_000048.3 170 agC/agT 0 +ASPSCR1 UCSF GRCh37 17 79968702 79968702 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 25 55 1 ENST00000306739.4:c.1195G>A p.Asp399Asn p.D399N ENST00000306739 NM_024083.3 399 Gac/Aac 0 +ASXL1 UCSF GRCh37 20 31022675 31022675 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 55 83 0 ENST00000375687.4:c.2160C>T p.Asp720= p.D720= ENST00000375687 NM_015338.5 720 gaC/gaT 0 +ASXL1 UCSF GRCh37 20 31023287 31023287 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 73 139 0 ENST00000375687.4:c.2772C>T p.Pro924= p.P924= ENST00000375687 NM_015338.5 924 ccC/ccT 0 +ATAD2 UCSF GRCh37 8 124384893 124384893 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P10_Rec Untested WXS Illumina HiSeq 46 0 ENST00000287394.5:c.354delA p.Glu119LysfsTer8 p.E119Kfs*8 ENST00000287394 NM_014109.3 118 aaA/aa 0 +ATAD2B UCSF GRCh37 2 24046250 24046250 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 138 95 188 0 ENST00000238789.5:c.2009C>T p.Ser670Phe p.S670F ENST00000238789 NM_001242338.1 670 tCt/tTt 0 +ATAD3C UCSF GRCh37 1 1394579 1394579 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 58 102 0 ENST00000378785.2:c.780C>T p.Ala260= p.A260= ENST00000378785 NM_001039211.2 260 gcC/gcT 0 +ATAD5 UCSF GRCh37 17 29196607 29196607 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 74 169 0 ENST00000321990.4:c.3550G>A p.Gly1184Ser p.G1184S ENST00000321990 NM_024857.3 1184 Ggt/Agt 0 +ATG13 UCSF GRCh37 11 46671819 46671819 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 112 202 0 ENST00000359513.4:c.410C>T p.Ala137Val p.A137V ENST00000359513 137 gCc/gTc 0 +ATG2A UCSF GRCh37 11 64674276 64674276 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 29 44 0 ENST00000377264.3:c.2844G>A p.Gly948= p.G948= ENST00000377264 NM_015104.2 948 ggG/ggA 0 +ATG2B UCSF GRCh37 14 96800741 96800741 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 34 89 0 ENST00000359933.4:c.1021+1G>A p.X341_splice ENST00000359933 NM_018036.5 0 +ATG4A UCSF GRCh37 X 107380354 107380354 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 62 213 0 ENST00000372232.3:c.501G>A p.Leu167= p.L167= ENST00000372232 NM_052936.3 167 ttG/ttA 0 +ATG4C UCSF GRCh37 1 63307111 63307111 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 40 122 0 ENST00000317868.4:c.1102C>T p.Pro368Ser p.P368S ENST00000317868 NM_032852.3 368 Cct/Tct 0 +ATG7 UCSF GRCh37 3 11348535 11348535 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 90 163 0 ENST00000354449.3:c.333+1G>A p.X111_splice ENST00000354449 NM_006395.2 0 +ATL2 UCSF GRCh37 2 38546043 38546043 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 87 155 0 ENST00000378954.4:c.482G>A p.Arg161Lys p.R161K ENST00000378954 NM_001135673.1 161 aGa/aAa 0 +ATL2 UCSF GRCh37 2 38525577 38525577 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 139 126 226 0 ENST00000378954.4:c.1341G>A p.Gln447= p.Q447= ENST00000378954 NM_001135673.1 447 caG/caA 0 +ATP11B UCSF GRCh37 3 182575747 182575747 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 92 173 0 ENST00000323116.5:c.933G>A p.Trp311Ter p.W311* ENST00000323116 NM_014616.2 311 tgG/tgA 0 +ATP13A3 UCSF GRCh37 3 194168634 194168634 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 112 178 0 ENST00000256031.4:c.1255G>A p.Ala419Thr p.A419T ENST00000256031 NM_024524.3 419 Gca/Aca 0 +ATP1A4 UCSF GRCh37 1 160128843 160128843 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 73 135 0 ENST00000368081.4:c.577G>A p.Val193Met p.V193M ENST00000368081 NM_144699.3 193 Gtg/Atg 0 +ATP2A2 UCSF GRCh37 12 110784078 110784078 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 63 179 0 ENST00000539276.2:c.2932C>T p.Leu978Phe p.L978F ENST00000539276 978 Ctc/Ttc 0 +ATP2A2 UCSF GRCh37 12 110778552 110778552 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 72 110 0 ENST00000539276.2:c.1850G>A p.Gly617Asp p.G617D ENST00000539276 617 gGc/gAc 0 +ATP2B1 UCSF GRCh37 12 89997948 89997948 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 60 99 0 ENST00000428670.3:c.2618G>A p.Gly873Asp p.G873D ENST00000428670 873 gGc/gAc 0 +ATP2B3 UCSF GRCh37 X 152807193 152807193 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 47 90 0 ENST00000263519.4:c.473C>T p.Ala158Val p.A158V ENST00000263519 NM_001001344.2 158 gCt/gTt 0 +ATP2B4 UCSF GRCh37 1 203690419 203690419 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 60 128 0 ENST00000357681.5:c.2693C>T p.Ser898Phe p.S898F ENST00000357681 NM_001684.4 898 tCt/tTt 0 +ATP2C2 UCSF GRCh37 16 84482283 84482283 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 62 102 0 ENST00000262429.4:c.1648C>T p.Leu550Phe p.L550F ENST00000262429 NM_014861.2 550 Ctc/Ttc 0 +ATP2C2 UCSF GRCh37 16 84442047 84442047 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 31 80 0 ENST00000262429.4:c.364G>A p.Ala122Thr p.A122T ENST00000262429 NM_014861.2 122 Gcc/Acc 0 +ATP6AP2 UCSF GRCh37 X 40456585 40456585 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 58 144 0 ENST00000378438.4:c.385C>T p.Pro129Ser p.P129S ENST00000378438 NM_005765.2 129 Ccc/Tcc 0 +ATP6V0D1 UCSF GRCh37 16 67472557 67472557 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 88 178 0 ENST00000290949.3:c.930C>T p.Phe310= p.F310= ENST00000290949 NM_004691.4 310 ttC/ttT 0 +ATP6V0D2 UCSF GRCh37 8 87126101 87126101 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 156 54 110 0 ENST00000285393.3:c.294C>T p.Thr98= p.T98= ENST00000285393 NM_152565.1 98 acC/acT 0 +ATP6V1A UCSF GRCh37 3 113503577 113503577 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 63 117 0 ENST00000273398.3:c.461G>A p.Gly154Glu p.G154E ENST00000273398 NM_001690.3 154 gGa/gAa 0 +ATP6V1B1 UCSF GRCh37 2 71192158 71192158 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 37 76 0 ENST00000234396.4:c.1449G>A p.Lys483= p.K483= ENST00000234396 NM_001692.3 483 aaG/aaA 0 +ATP6V1G1 UCSF GRCh37 9 117350193 117350193 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 8 11 0 ENST00000374050.3:c.75C>T p.Ala25= p.A25= ENST00000374050 NM_004888.3 25 gcC/gcT 0 +ATP6V1G2 UCSF GRCh37 6 31513939 31513939 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 54 119 0 ENST00000303892.5:c.130G>A p.Val44Met p.V44M ENST00000303892 NM_138282.2 44 Gtg/Atg 0 +ATP7B UCSF GRCh37 13 52542627 52542627 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 78 136 0 ENST00000242839.4:c.1660G>A p.Ala554Thr p.A554T ENST00000242839 NM_000053.3 554 Gca/Aca 0 +ATP7B UCSF GRCh37 13 52520511 52520511 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 16 40 0 ENST00000242839.4:c.2969C>T p.Ala990Val p.A990V ENST00000242839 NM_000053.3 990 gCc/gTc 0 +ATP7B UCSF GRCh37 13 52548653 52548653 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 105 211 0 ENST00000242839.4:c.703C>T p.Pro235Ser p.P235S ENST00000242839 NM_000053.3 235 Cct/Tct 0 +ATP8A1 UCSF GRCh37 4 42487635 42487635 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 70 195 0 ENST00000381668.5:c.2202C>T p.Leu734= p.L734= ENST00000381668 NM_006095.2 734 ctC/ctT 0 +ATP8B4 UCSF GRCh37 15 50189676 50189676 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 128 220 0 ENST00000284509.6:c.2510G>A p.Gly837Glu p.G837E ENST00000284509 NM_024837.3 837 gGa/gAa 0 +ATP8B4 UCSF GRCh37 15 50273457 50273457 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 40 112 0 ENST00000284509.6:c.783G>A p.Lys261= p.K261= ENST00000284509 NM_024837.3 261 aaG/aaA 0 +ATP9A UCSF GRCh37 20 50245563 50245563 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 85 190 0 ENST00000338821.5:c.1717G>A p.Val573Ile p.V573I ENST00000338821 NM_006045.1 573 Gtc/Atc 0 +ATP9B UCSF GRCh37 18 77097371 77097371 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 34 92 0 ENST00000426216.2:c.2205G>A p.Leu735= p.L735= ENST00000426216 NM_198531.3 735 ctG/ctA 0 +ATPBD4 UCSF GRCh37 15 35814403 35814403 + intron_variant Intron SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 49 101 0 ENST00000256538.4:c.312+16072G>A *104* ENST00000256538 NM_080650.3 0 +ATR UCSF GRCh37 3 142279142 142279142 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 71 175 0 ENST00000350721.4:c.1504C>T p.Leu502= p.L502= ENST00000350721 NM_001184.3 502 Ctg/Ttg 0 +ATRN UCSF GRCh37 20 3553565 3553565 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 59 161 0 ENST00000262919.5:c.2059G>A p.Glu687Lys p.E687K ENST00000262919 NM_139321.2 687 Gaa/Aaa 0 +ATRX UCSF GRCh37 X 76814225 76814225 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 75 68 168 0 ENST00000373344.5:c.6419A>G p.Asn2140Ser p.N2140S ENST00000373344 NM_000489.3 2140 aAt/aGt 0 +ATXN3L UCSF GRCh37 X 13337642 13337642 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 107 228 0 ENST00000380622.2:c.412G>A p.Ala138Thr p.A138T ENST00000380622 NM_001135995.1 138 Gcg/Acg 0 +AUTS2 UCSF GRCh37 7 70254999 70254999 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 27 35 0 ENST00000342771.4:c.2797G>A p.Ala933Thr p.A933T ENST00000342771 NM_015570.2 933 Gcc/Acc 0 +AVL9 UCSF GRCh37 7 32598829 32598829 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 55 126 0 ENST00000318709.4:c.968C>T p.Ser323Phe p.S323F ENST00000318709 NM_015060.1 323 tCt/tTt 0 +AVL9 UCSF GRCh37 7 32598950 32598950 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 56 118 0 ENST00000318709.4:c.1089C>T p.Val363= p.V363= ENST00000318709 NM_015060.1 363 gtC/gtT 0 +AVPR1B UCSF GRCh37 1 206230814 206230814 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 20 47 0 ENST00000367126.4:c.947C>T p.Thr316Ile p.T316I ENST00000367126 NM_000707.3 316 aCc/aTc 0 +AXIN1 UCSF GRCh37 16 347811 347811 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 10 25 0 ENST00000262320.3:c.1695C>T p.Gly565= p.G565= ENST00000262320 NM_003502.3 565 ggC/ggT 0 +AXL UCSF GRCh37 19 41759510 41759510 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 20 52 0 ENST00000301178.4:c.1933C>T p.Pro645Ser p.P645S ENST00000301178 NM_021913.4 645 Ccc/Tcc 0 +B4GALNT4 UCSF GRCh37 11 375904 375904 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 1 17 27 0 ENST00000329962.6:c.1043C>T p.Pro348Leu p.P348L ENST00000329962 NM_178537.4 348 cCc/cTc 0 +B4GALT2 UCSF GRCh37 1 44447467 44447467 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 43 85 0 ENST00000356836.6:c.420C>T p.Thr140= p.T140= ENST00000356836 NM_001005417.2 140 acC/acT 0 +BAG2 UCSF GRCh37 6 57048760 57048760 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 80 183 0 ENST00000370693.5:c.408G>A p.Met136Ile p.M136I ENST00000370693 NM_004282.3 136 atG/atA 0 +BAG2 UCSF GRCh37 6 57048888 57048888 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 63 152 0 ENST00000370693.5:c.536G>A p.Arg179Lys p.R179K ENST00000370693 NM_004282.3 179 aGa/aAa 0 +BAHD1 UCSF GRCh37 15 40758176 40758176 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 80 131 0 ENST00000416165.1:c.2190C>T p.Leu730= p.L730= ENST00000416165 NM_014952.3 730 ctC/ctT 0 +BAI1 UCSF GRCh37 8 143545905 143545905 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 8 17 0 ENST00000323289.5:c.346G>A p.Gly116Ser p.G116S ENST00000323289 NM_001702.2 116 Ggc/Agc 0 +BAIAP2L1 UCSF GRCh37 7 97935766 97935766 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 52 121 0 ENST00000005260.8:c.1226C>T p.Thr409Ile p.T409I ENST00000005260 NM_018842.4 409 aCc/aTc 0 +BAZ2B UCSF GRCh37 2 160287578 160287578 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 80 157 0 ENST00000392783.2:c.1990G>A p.Glu664Lys p.E664K ENST00000392783 NM_013450.2 664 Gaa/Aaa 0 +BBS1 UCSF GRCh37 11 66283022 66283022 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 54 134 0 ENST00000318312.7:c.444C>T p.Asp148= p.D148= ENST00000318312 NM_024649.4 148 gaC/gaT 0 +BBS12 UCSF GRCh37 4 123663752 123663752 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 82 214 0 ENST00000314218.3:c.705G>A p.Arg235= p.R235= ENST00000314218 NM_152618.2 235 agG/agA 0 +BBS4 UCSF GRCh37 15 73009191 73009191 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 16 46 0 ENST00000268057.4:c.405G>A p.Trp135Ter p.W135* ENST00000268057 NM_033028.4 135 tgG/tgA 0 +BCAS1 UCSF GRCh37 20 52645014 52645014 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 116 104 205 0 ENST00000395961.3:c.640G>A p.Glu214Lys p.E214K ENST00000395961 NM_003657.2 214 Gaa/Aaa 0 +BCL11A UCSF GRCh37 2 60679739 60679739 + downstream_gene_variant 3'Flank SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 68 126 0 ENST00000335712 NM_022893.3 0 +BCL11A UCSF GRCh37 2 60773220 60773220 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 84 188 0 ENST00000335712.6:c.271G>A p.Glu91Lys p.E91K ENST00000335712 NM_022893.3 91 Gag/Aag 0 +BCL11B UCSF GRCh37 14 99697883 99697883 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 11 0 ENST00000357195.3:c.439C>T p.Pro147Ser p.P147S ENST00000357195 NM_138576.2 147 Cct/Tct 0 +BCL2L11 UCSF GRCh37 2 111907635 111907635 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 31 72 0 ENST00000393256.3:c.409G>A p.Ala137Thr p.A137T ENST00000393256 NM_006538.4 137 Gct/Act 0 +BCL3 UCSF GRCh37 19 45260369 45260369 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 12 15 0 ENST00000164227.5:c.615C>T p.Gly205= p.G205= ENST00000164227 NM_005178.4 205 ggC/ggT 0 +BCOR UCSF GRCh37 X 39932533 39932533 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 53 81 0 ENST00000378444.4:c.2066G>A p.Gly689Asp p.G689D ENST00000378444 NM_001123385.1 689 gGc/gAc 0 +BCORL1 UCSF GRCh37 X 129171444 129171444 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 57 128 0 ENST00000218147.7:c.4408G>A p.Asp1470Asn p.D1470N ENST00000218147 1470 Gac/Aac 0 +BEAN1 UCSF GRCh37 16 66514512 66514512 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 19 24 0 ENST00000536005.2:c.464G>A p.Gly155Glu p.G155E ENST00000536005 NM_001178020.2 155 gGg/gAg 0 +BEST1 UCSF GRCh37 11 61724400 61724400 + missense_variant Missense_Mutation SNP C C T snp132_rs62639357 P10_Rec Untested WXS Illumina HiSeq 118 86 163 0 ENST00000378043.4:c.566C>T p.Ala189Val p.A189V ENST00000378043 NM_004183.3 189 gCc/gTc 0 +BEST1 UCSF GRCh37 11 61730351 61730351 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 55 140 0 ENST00000378043.4:c.1725G>A p.Trp575Ter p.W575* ENST00000378043 NM_004183.3 575 tgG/tgA 0 +BIN2 UCSF GRCh37 12 51696470 51696470 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 75 167 0 ENST00000267012.4:c.312G>A p.Trp104Ter p.W104* ENST00000267012 NM_016293.2 104 tgG/tgA 0 +BIN3 UCSF GRCh37 8 22479058 22479058 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 35 105 0 ENST00000276416.6:c.639C>T p.His213= p.H213= ENST00000276416 NM_018688.4 213 caC/caT 0 +BIRC6 UCSF GRCh37 2 32824908 32824908 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 85 209 0 ENST00000421745.2:c.13933C>T p.Leu4645= p.L4645= ENST00000421745 NM_016252.3 4645 Cta/Tta 0 +BIRC7 UCSF GRCh37 20 61870934 61870934 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 25 24 0 ENST00000217169.3:c.874C>T p.Arg292Cys p.R292C ENST00000217169 NM_139317.2 292 Cgc/Tgc 0 +BIRC7 UCSF GRCh37 20 61869332 61869332 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 17 38 0 ENST00000217169.3:c.427G>A p.Glu143Lys p.E143K ENST00000217169 NM_139317.2 143 Gag/Aag 0 +BIVM UCSF GRCh37 13 103474475 103474475 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 45 136 0 ENST00000257336.1:c.867G>A p.Lys289= p.K289= ENST00000257336 NM_017693.3 289 aaG/aaA 0 +BLNK UCSF GRCh37 10 98002540 98002540 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 46 125 0 ENST00000224337.5:c.114G>A p.Lys38= p.K38= ENST00000224337 NM_013314.3 38 aaG/aaA 0 +BLVRA UCSF GRCh37 7 43840116 43840116 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 38 80 0 ENST00000265523.4:c.405C>T p.Phe135= p.F135= ENST00000265523 NM_000712.3 135 ttC/ttT 0 +BMP1 UCSF GRCh37 8 22058659 22058659 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 45 99 0 ENST00000306385.5:c.2108-657G>A *703* ENST00000306385 NM_006129.4 0 +BMP15 UCSF GRCh37 X 50659331 50659331 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 69 165 0 ENST00000252677.3:c.903C>T p.Arg301= p.R301= ENST00000252677 NM_005448.2 301 cgC/cgT 0 +BMPER UCSF GRCh37 7 33976972 33976972 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 41 105 0 ENST00000297161.2:c.291G>A p.Gln97= p.Q97= ENST00000297161 NM_133468.4 97 caG/caA 0 +BNC1 UCSF GRCh37 15 83932486 83932486 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 56 143 0 ENST00000345382.2:c.1517G>A p.Gly506Glu p.G506E ENST00000345382 NM_001717.3 506 gGg/gAg 0 +BNC1 UCSF GRCh37 15 83932013 83932013 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 79 151 0 ENST00000345382.2:c.1990C>T p.Pro664Ser p.P664S ENST00000345382 NM_001717.3 664 Ccc/Tcc 0 +BNIP2 UCSF GRCh37 15 59970244 59970244 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 105 221 0 ENST00000607373.1:c.338G>A p.Gly113Asp p.G113D ENST00000607373 NM_004330.2 113 gGc/gAc 0 +BOD1L UCSF GRCh37 4 13604919 13604919 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 134 126 202 0 ENST00000040738.5:c.3605C>T p.Thr1202Ile p.T1202I ENST00000040738 NM_148894.2 1202 aCc/aTc 0 +BOP1 UCSF GRCh37 8 145512976 145512976 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 105 24 61 0 ENST00000307404.5:c.109C>T p.Leu37Phe p.L37F ENST00000307404 NM_015201.3 37 Ctc/Ttc 0 +BPGM UCSF GRCh37 7 134346447 134346447 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 68 126 0 ENST00000344924.3:c.188C>T p.Ser63Phe p.S63F ENST00000344924 NM_001724.4 63 tCc/tTc 0 +BRAT1 UCSF GRCh37 7 2587021 2587021 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 40 66 0 ENST00000340611.4:c.219C>T p.Leu73= p.L73= ENST00000340611 NM_152743.3 73 ctC/ctT 0 +BRCA1 UCSF GRCh37 17 41201137 41201137 + splice_donor_variant Splice_Site SNP C C T snp132_rs80358028 P10_Rec somatic WXS Sanger Illumina HiSeq 50 39 83 0 ENST00000357654.3:c.5406+1G>A p.X1802_splice ENST00000357654 NM_007294.3 0 +BRD2 UCSF GRCh37 6 32945348 32945348 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 87 187 0 ENST00000374825.4:c.1329+1G>A p.X443_splice ENST00000374825 NM_005104.3 0 +BRD2 UCSF GRCh37 6 32947668 32947668 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 39 126 0 ENST00000374825.4:c.1905G>A p.Glu635= p.E635= ENST00000374825 NM_005104.3 635 gaG/gaA 0 +BRD3 UCSF GRCh37 9 136917491 136917491 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 119 50 117 0 ENST00000303407.7:c.288G>A p.Trp96Ter p.W96* ENST00000303407 NM_007371.3 96 tgG/tgA 0 +BRD8 UCSF GRCh37 5 137513329 137513329 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 83 133 0 ENST00000254900.5:c.47C>T p.Thr16Ile p.T16I ENST00000254900 NM_139199.1 16 aCa/aTa 0 +BRF2 UCSF GRCh37 8 37707147 37707147 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 33 72 0 ENST00000220659.6:c.154+1G>A p.X52_splice ENST00000220659 NM_018310.3 0 +BRPF1 UCSF GRCh37 3 9782593 9782593 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 38 103 0 ENST00000457855.1:c.1690C>T p.Leu564= p.L564= ENST00000457855 564 Ctg/Ttg 0 +BRPF3 UCSF GRCh37 6 36169066 36169066 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 32 90 0 ENST00000357641.6:c.967C>T p.Leu323= p.L323= ENST00000357641 NM_015695.2 323 Cta/Tta 0 +BRWD1 UCSF GRCh37 21 40670433 40670433 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 76 186 0 ENST00000333229.2:c.274G>A p.Glu92Lys p.E92K ENST00000333229 NM_018963.4 92 Gaa/Aaa 0 +BSN UCSF GRCh37 3 49680186 49680186 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 41 74 0 ENST00000296452.4:c.1119C>T p.Thr373= p.T373= ENST00000296452 NM_003458.3 373 acC/acT 0 +BTBD2 UCSF GRCh37 19 1987249 1987249 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 18 61 0 ENST00000255608.4:c.1185C>T p.Phe395= p.F395= ENST00000255608 NM_017797.3 395 ttC/ttT 0 +BTN2A2 UCSF GRCh37 6 26390245 26390245 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 51 171 0 ENST00000356709.4:c.737C>T p.Pro246Leu p.P246L ENST00000356709 NM_001197240.1 246 cCc/cTc 0 +BTNL8 UCSF GRCh37 5 180376251 180376251 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 44 122 0 ENST00000340184.4:c.848C>T p.Ala283Val p.A283V ENST00000340184 NM_001040462.2 283 gCc/gTc 0 +BTNL8 UCSF GRCh37 5 180375366 180375366 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 145 125 273 0 ENST00000340184.4:c.799G>A p.Ala267Thr p.A267T ENST00000340184 NM_001040462.2 267 Gcg/Acg 0 +C10orf120 UCSF GRCh37 10 124459232 124459232 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 64 155 0 ENST00000329446.4:c.75G>A p.Arg25= p.R25= ENST00000329446 NM_001010912.2 25 agG/agA 0 +C11orf30 UCSF GRCh37 11 76234205 76234205 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 102 214 0 ENST00000334736.3:c.1691C>T p.Thr564Ile p.T564I ENST00000334736 NM_020193.3 564 aCt/aTt 0 +C11orf31 UCSF GRCh37 11 57509417 57509417 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 26 49 0 ENST00000388857.4:c.259G>A p.Asp87Asn p.D87N ENST00000388857 87 Gac/Aac 0 +C11orf88 UCSF GRCh37 11 111386773 111386773 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 61 152 0 ENST00000375618.4:c.277G>A p.Asp93Asn p.D93N ENST00000375618 NM_001100388.1 93 Gac/Aac 0 +C11orf9 UCSF GRCh37 11 61550970 61550970 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 77 168 0 ENST00000278836.5:c.3017C>T p.Ala1006Val p.A1006V ENST00000278836 NM_001127392.1 1006 gCc/gTc 0 +C12orf34 UCSF GRCh37 12 110206997 110206997 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 16 24 0 ENST00000358906.3:c.1263C>T p.Ile421= p.I421= ENST00000358906 421 atC/atT 0 +C12orf48 UCSF GRCh37 12 102542198 102542198 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 93 144 0 ENST00000327680.2:c.101G>A p.Arg34Lys p.R34K ENST00000327680 NM_017915.3 34 aGg/aAg 0 +C12orf54 UCSF GRCh37 12 48888711 48888711 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 74 166 0 ENST00000314014.2:c.373C>T p.Pro125Ser p.P125S ENST00000314014 NM_152319.3 125 Cct/Tct 0 +C12orf54 UCSF GRCh37 12 48886731 48886731 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 29 84 0 ENST00000314014.2:c.195G>A p.Gly65= p.G65= ENST00000314014 NM_152319.3 65 ggG/ggA 0 +C14orf159 UCSF GRCh37 14 91671083 91671083 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 22 56 0 ENST00000428926.2:c.1463G>A p.Gly488Asp p.G488D ENST00000428926 NM_024952.6 488 gGt/gAt 0 +C14orf159 UCSF GRCh37 14 91691107 91691107 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 27 52 0 ENST00000428926.2:c.1781G>A p.Gly594Glu p.G594E ENST00000428926 NM_024952.6 594 gGg/gAg 0 +C14orf38 UCSF GRCh37 14 60027919 60027919 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 58 122 0 ENST00000537690.2:c.871G>A p.Ala291Thr p.A291T ENST00000537690 NM_001164399.1 291 Gca/Aca 0 +C14orf49 UCSF GRCh37 14 95921754 95921754 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 39 49 0 ENST00000334258.5:c.1097G>A p.Gly366Glu p.G366E ENST00000334258 NM_152592.3 366 gGg/gAg 0 +C15orf23 UCSF GRCh37 15 40683693 40683693 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 47 125 0 ENST00000249776.8:c.686-1G>A p.X229_splice ENST00000249776 NM_033286.3 0 +C15orf33 UCSF GRCh37 15 49659753 49659753 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 50 138 0 ENST00000299338.6:c.1163G>A p.Gly388Glu p.G388E ENST00000299338 NM_152647.2 388 gGa/gAa 0 +C15orf40 UCSF GRCh37 15 83677377 83677377 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 72 162 0 ENST00000304177.5:c.208G>A p.Gly70Arg p.G70R ENST00000304177 NM_144597.2 70 Gga/Aga 0 +C15orf42 UCSF GRCh37 15 90167242 90167242 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 97 180 0 ENST00000268138.7:c.3701C>T p.Ala1234Val p.A1234V ENST00000268138 1234 gCc/gTc 0 +C15orf42 UCSF GRCh37 15 90119379 90119379 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 30 66 0 ENST00000268138.7:c.562G>A p.Val188Met p.V188M ENST00000268138 188 Gtg/Atg 0 +C16orf3 UCSF GRCh37 16 90095702 90095702 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 29 69 0 ENST00000408886.2:c.49C>T p.Pro17Ser p.P17S ENST00000408886 NM_001214.3 17 Ccc/Tcc 0 +C16orf48 UCSF GRCh37 16 67698965 67698965 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 56 148 0 ENST00000243878.4:c.387C>T p.Pro129= p.P129= ENST00000243878 NM_032140.1 129 ccC/ccT 0 +C17orf104 UCSF GRCh37 17 42743859 42743859 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 110 244 0 ENST00000409122.2:c.580G>A p.Ala194Thr p.A194T ENST00000409122 NM_001145080.2 194 Gct/Act 0 +C17orf47 UCSF GRCh37 17 56620740 56620740 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 107 214 0 ENST00000321691.3:c.808G>A p.Asp270Asn p.D270N ENST00000321691 NM_001038704.2 270 Gac/Aac 0 +C17orf63 UCSF GRCh37 17 27086333 27086333 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 12 40 0 ENST00000452648.3:c.644C>T p.Ala215Val p.A215V ENST00000452648 215 gCt/gTt 0 +C17orf87 UCSF GRCh37 17 5114220 5114220 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 56 114 0 ENST00000574081.1:c.314C>T p.Ala105Val p.A105V ENST00000574081 NM_001271842.1 105 gCt/gTt 0 +C17orf87 UCSF GRCh37 17 5126707 5126707 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 49 211 0 ENST00000574081.1:c.66C>T p.Ile22= p.I22= ENST00000574081 NM_001271842.1 22 atC/atT 0 +C18orf45 UCSF GRCh37 18 20878020 20878020 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 37 75 0 ENST00000383233.3:c.842G>A p.Gly281Asp p.G281D ENST00000383233 NM_032933.4 281 gGt/gAt 0 +C19orf12 UCSF GRCh37 19 30199172 30199172 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 59 128 0 ENST00000392278.2:c.182G>A p.Gly61Glu p.G61E ENST00000392278 NM_001031726.3 61 gGa/gAa 0 +C19orf21 UCSF GRCh37 19 758600 758600 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 47 74 0 ENST00000215582.6:c.1654G>A p.Glu552Lys p.E552K ENST00000215582 NM_173481.2 552 Gag/Aag 0 +C19orf22 UCSF GRCh37 19 902122 902122 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 26 69 0 ENST00000361574.5:c.80C>T p.Pro27Leu p.P27L ENST00000361574 NM_138774.3 27 cCc/cTc 0 +C19orf44 UCSF GRCh37 19 16625456 16625456 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 11 22 0 ENST00000221671.3:c.1884C>T p.Thr628= p.T628= ENST00000221671 NM_032207.2 628 acC/acT 0 +C1orf227 UCSF GRCh37 1 213009442 213009442 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 78 204 0 ENST00000332912.3:c.50G>A p.Ser17Asn p.S17N ENST00000332912 NM_001024601.2 17 aGc/aAc 0 +C1orf27 UCSF GRCh37 1 186349002 186349002 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 76 191 0 ENST00000287859.6:c.85C>T p.Leu29Phe p.L29F ENST00000287859 NM_017847.5 29 Ctt/Ttt 0 +C1orf53 UCSF GRCh37 1 197874934 197874934 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 98 95 175 0 ENST00000367393.3:c.273G>A p.Gln91= p.Q91= ENST00000367393 NM_001024594.2 91 caG/caA 0 +C1orf85 UCSF GRCh37 1 156264741 156264741 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 46 96 0 ENST00000362007.1:c.187G>A p.Gly63Ser p.G63S ENST00000362007 NM_001256609.1 63 Ggc/Agc 0 +C1orf87 UCSF GRCh37 1 60505833 60505833 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 77 151 0 ENST00000371201.3:c.503G>A p.Ser168Asn p.S168N ENST00000371201 NM_152377.2 168 aGt/aAt 0 +C1QA UCSF GRCh37 1 22964259 22964259 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 23 1 ENST00000374642.3:c.150G>A p.Glu50= p.E50= ENST00000374642 NM_015991.2 50 gaG/gaA 0 +C1QTNF1 UCSF GRCh37 17 77042661 77042661 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 81 127 0 ENST00000339142.2:c.180C>T p.Tyr60= p.Y60= ENST00000339142 NM_198593.3 60 taC/taT 0 +C1QTNF5 UCSF GRCh37 11 119210158 119210158 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 53 106 0 ENST00000528368.1:c.615G>A p.Val205= p.V205= ENST00000528368 NM_001278431.1 205 gtG/gtA 0 +C1R UCSF GRCh37 12 7242704 7242704 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 46 104 0 ENST00000542285.1:c.369G>A p.Glu123= p.E123= ENST00000542285 123 gaG/gaA 0 +C20orf103 UCSF GRCh37 20 9496254 9496254 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 90 162 0 ENST00000246070.2:c.219G>A p.Trp73Ter p.W73* ENST00000246070 NM_012261.3 73 tgG/tgA 0 +C20orf165 UCSF GRCh37 20 44515234 44515234 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 73 133 0 ENST00000372519.3:c.606G>A p.Gln202= p.Q202= ENST00000372519 NM_080608.3 202 caG/caA 0 +C20orf26 UCSF GRCh37 20 20177327 20177327 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 137 141 215 0 ENST00000245957.5:c.1704G>A p.Arg568= p.R568= ENST00000245957 NM_015585.3 568 cgG/cgA 0 +C20orf43 UCSF GRCh37 20 55052172 55052172 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 47 69 0 ENST00000357348.5:c.480C>T p.Gly160= p.G160= ENST00000357348 NM_001283035.1 160 ggC/ggT 0 +C21orf62 UCSF GRCh37 21 34166277 34166277 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 60 108 0 ENST00000479548.1:c.456G>A p.Glu152= p.E152= ENST00000479548 152 gaG/gaA 0 +C22orf29 UCSF GRCh37 22 19839078 19839078 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 63 121 0 ENST00000328554.4:c.707C>T p.Ala236Val p.A236V ENST00000328554 NM_024627.5 236 gCc/gTc 0 +C2orf49 UCSF GRCh37 2 105959619 105959619 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 55 146 0 ENST00000258457.2:c.581C>T p.Pro194Leu p.P194L ENST00000258457 194 cCt/cTt 0 +C2orf53 UCSF GRCh37 2 27360284 27360284 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 36 76 0 ENST00000335524.3:c.914G>A p.Gly305Asp p.G305D ENST00000335524 NM_178553.3 305 gGc/gAc 0 +C2orf78 UCSF GRCh37 2 74041181 74041181 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 134 109 249 0 ENST00000409561.1:c.675C>T p.Cys225= p.C225= ENST00000409561 NM_001080474.1 225 tgC/tgT 0 +C2orf80 UCSF GRCh37 2 209046029 209046029 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 44 132 0 ENST00000341287.4:c.207G>A p.Leu69= p.L69= ENST00000341287 NM_001099334.2 69 ctG/ctA 0 +C3orf20 UCSF GRCh37 3 14768455 14768455 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 60 113 0 ENST00000253697.3:c.1614C>T p.Ser538= p.S538= ENST00000253697 NM_032137.4 538 agC/agT 0 +C3orf77 UCSF GRCh37 3 44312208 44312208 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 52 117 0 ENST00000309765.4:c.3278C>T p.Pro1093Leu p.P1093L ENST00000309765 NM_001145030.1 1093 cCc/cTc 0 +C5 UCSF GRCh37 9 123785682 123785682 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 250 125 231 0 ENST00000223642.1:c.1116G>A p.Lys372= p.K372= ENST00000223642 NM_001735.2 372 aaG/aaA 0 +C6orf162 UCSF GRCh37 6 88046815 88046815 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 65 160 0 ENST00000229570.5:c.66C>T p.Ser22= p.S22= ENST00000229570 NM_020425.4 22 agC/agT 0 +C6orf211 UCSF GRCh37 6 151775763 151775763 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 50 138 0 ENST00000367294.3:c.122G>A p.Ser41Asn p.S41N ENST00000367294 NM_024573.1 41 aGt/aAt 0 +C6orf26 UCSF GRCh37 6 31732246 31732246 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 34 101 0 ENST00000425424.1:c.385C>T p.Pro129Ser p.P129S ENST00000425424 129 Cca/Tca 0 +C6orf97 UCSF GRCh37 6 151917610 151917610 + synonymous_variant Silent SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 74 74 154 0 ENST00000239374.7:c.1608G>A p.Arg536= p.R536= ENST00000239374 NM_025059.3 536 agG/agA 0 +C6orf97 UCSF GRCh37 6 151907095 151907095 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 25 79 0 ENST00000239374.7:c.1164G>A p.Gln388= p.Q388= ENST00000239374 NM_025059.3 388 caG/caA 0 +C7orf25 UCSF GRCh37 7 42950222 42950222 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 120 114 200 0 ENST00000350427.4:c.278G>A p.Gly93Asp p.G93D ENST00000350427 93 gGt/gAt 0 +C8B UCSF GRCh37 1 57399066 57399066 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 112 0 ENST00000371237.4:c.1494G>A p.Lys498= p.K498= ENST00000371237 NM_000066.3 498 aaG/aaA 0 +C8orf58 UCSF GRCh37 8 22459558 22459558 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 13 16 0 ENST00000289989.5:c.731G>A p.Gly244Glu p.G244E ENST00000289989 244 gGg/gAg 0 +C9orf172 UCSF GRCh37 9 139741661 139741661 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 13 11 0 ENST00000436881.1:c.2795G>A p.Arg932Lys p.R932K ENST00000436881 NM_001080482.2 932 aGg/aAg 0 +C9orf172 UCSF GRCh37 9 139739794 139739794 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 42 22 46 0 ENST00000436881.1:c.928T>C p.Tyr310His p.Y310H ENST00000436881 NM_001080482.2 310 Tat/Cat 0 +C9orf79 UCSF GRCh37 9 90499973 90499973 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 161 64 124 0 ENST00000325643.5:c.571C>T p.Pro191Ser p.P191S ENST00000325643 NM_178828.4 191 Cca/Tca 0 +C9orf79 UCSF GRCh37 9 90500779 90500779 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 201 106 183 0 ENST00000325643.5:c.1377G>A p.Arg459= p.R459= ENST00000325643 NM_178828.4 459 agG/agA 0 +C9orf86 UCSF GRCh37 9 139726289 139726289 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 33 63 0 ENST00000311502.7:c.575G>A p.Arg192His p.R192H ENST00000311502 192 cGt/cAt 0 +C9orf96 UCSF GRCh37 9 136268843 136268843 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 17 54 0 ENST00000371957.3:c.1494C>T p.Ala498= p.A498= ENST00000371957 NM_153710.4 498 gcC/gcT 0 +CA11 UCSF GRCh37 19 49143459 49143459 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 37 92 0 ENST00000084798.4:c.364G>A p.Gly122Ser p.G122S ENST00000084798 NM_001217.3 122 Ggt/Agt 0 +CA2 UCSF GRCh37 8 86377684 86377684 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 43 99 0 ENST00000285379.5:c.218C>T p.Ser73Phe p.S73F ENST00000285379 NM_000067.2 73 tCt/tTt 0 +CA8 UCSF GRCh37 8 61135318 61135318 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 44 100 0 ENST00000317995.4:c.628C>T p.Pro210Ser p.P210S ENST00000317995 NM_004056.4 210 Cct/Tct 0 +CACNA1B UCSF GRCh37 9 141015928 141015928 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 20 39 0 ENST00000371372.1:c.6497G>A p.Gly2166Asp p.G2166D ENST00000371372 NM_001243812.1 2166 gGt/gAt 0 +CACNA1B UCSF GRCh37 9 140811871 140811871 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 178 77 151 0 ENST00000371372.1:c.954C>T p.Asp318= p.D318= ENST00000371372 NM_001243812.1 318 gaC/gaT 0 +CACNA1B UCSF GRCh37 9 141012494 141012494 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 29 49 0 ENST00000371372.1:c.5874C>T p.Gly1958= p.G1958= ENST00000371372 NM_001243812.1 1958 ggC/ggT 0 +CACNA1C UCSF GRCh37 12 2614007 2614007 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 69 134 0 ENST00000347598.4:c.1114-1G>A p.X372_splice ENST00000347598 NM_199460.2 0 +CACNA1C UCSF GRCh37 12 2675744 2675744 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 32 55 0 ENST00000347598.4:c.1665C>T p.Val555= p.V555= ENST00000347598 NM_199460.2 555 gtC/gtT 0 +CACNA1H UCSF GRCh37 16 1260652 1260652 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 37 49 0 ENST00000348261.5:c.4038+1G>A p.X1346_splice ENST00000348261 NM_021098.2 0 +CACNA2D2 UCSF GRCh37 3 50404048 50404048 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 23 52 0 ENST00000479441.1:c.2619C>T p.Pro873= p.P873= ENST00000479441 873 ccC/ccT 0 +CACNA2D3 UCSF GRCh37 3 54880479 54880479 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 50 126 0 ENST00000288197.5:c.1611G>A p.Pro537= p.P537= ENST00000288197 537 ccG/ccA 0 +CACNA2D4 UCSF GRCh37 12 1910226 1910226 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 28 56 0 ENST00000382722.5:c.2851G>A p.Ala951Thr p.A951T ENST00000382722 NM_172364.4 951 Gcc/Acc 0 +CACNA2D4 UCSF GRCh37 12 2022207 2022207 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 57 131 1 ENST00000382722.5:c.408G>A p.Arg136= p.R136= ENST00000382722 NM_172364.4 136 agG/agA 0 +CADM1 UCSF GRCh37 11 115109292 115109292 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 73 143 0 ENST00000452722.3:c.352G>A p.Asp118Asn p.D118N ENST00000452722 NM_014333.3 118 Gat/Aat 0 +CADPS2 UCSF GRCh37 7 122377008 122377008 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 63 178 0 ENST00000449022.2:c.453+1G>A p.X151_splice ENST00000449022 NM_017954.10 0 +CADPS2 UCSF GRCh37 7 122303612 122303612 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 76 183 0 ENST00000449022.2:c.465G>A p.Lys155= p.K155= ENST00000449022 NM_017954.10 155 aaG/aaA 0 +CADPS2 UCSF GRCh37 7 122377060 122377060 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 63 157 0 ENST00000449022.2:c.402C>T p.Thr134= p.T134= ENST00000449022 NM_017954.10 134 acC/acT 0 +CALCB UCSF GRCh37 11 15098966 15098966 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 36 97 0 ENST00000324229.6:c.359G>A p.Arg120Lys p.R120K ENST00000324229 NM_000728.3 120 aGg/aAg 0 +CAMKK2 UCSF GRCh37 12 121687675 121687675 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 40 130 0 ENST00000324774.5:c.1238C>T p.Pro413Leu p.P413L ENST00000324774 NM_006549.3 413 cCc/cTc 0 +CAMKK2 UCSF GRCh37 12 121711908 121711908 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 10 13 0 ENST00000324774.5:c.422C>T p.Pro141Leu p.P141L ENST00000324774 NM_006549.3 141 cCc/cTc 0 +CAMTA2 UCSF GRCh37 17 4876206 4876206 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 64 100 0 ENST00000348066.3:c.2361C>T p.Asp787= p.D787= ENST00000348066 NM_015099.3 787 gaC/gaT 0 +CAND1 UCSF GRCh37 12 67696174 67696174 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 103 188 0 ENST00000545606.1:c.1072G>A p.Asp358Asn p.D358N ENST00000545606 NM_018448.3 358 Gat/Aat 0 +CARD11 UCSF GRCh37 7 2977659 2977659 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 64 63 136 0 ENST00000396946.4:c.1025A>G p.Glu342Gly p.E342G ENST00000396946 NM_032415.4 342 gAg/gGg 0 +CARD14 UCSF GRCh37 17 78169384 78169384 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 16 29 0 ENST00000344227.2:c.1527C>T p.Asp509= p.D509= ENST00000344227 NM_024110.4 509 gaC/gaT 0 +CARD17 UCSF GRCh37 11 104971470 104971470 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 131 125 228 0 ENST00000375707.1:c.44G>A p.Arg15His p.R15H ENST00000375707 NM_001007232.1 15 cGt/cAt 0 +CARD9 UCSF GRCh37 9 139265296 139265296 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 21 57 0 ENST00000371732.5:c.624G>A p.Leu208= p.L208= ENST00000371732 NM_052813.4 208 ctG/ctA 0 +CASC5 UCSF GRCh37 15 40915103 40915103 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 99 194 0 ENST00000346991.5:c.2719G>A p.Glu907Lys p.E907K ENST00000346991 907 Gaa/Aaa 0 +CASKIN2 UCSF GRCh37 17 73501718 73501718 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 60 116 0 ENST00000321617.3:c.850C>T p.Leu284= p.L284= ENST00000321617 NM_020753.4 284 Ctg/Ttg 0 +CASP7 UCSF GRCh37 10 115481526 115481526 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 58 147 0 ENST00000345633.4:c.364C>T p.Leu122= p.L122= ENST00000345633 NM_033339.4 122 Ctg/Ttg 0 +CASR UCSF GRCh37 3 122003642 122003642 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 61 65 0 ENST00000490131.1:c.2841C>T p.Pro947= p.P947= ENST00000490131 NM_000388.3 947 ccC/ccT 0 +CAST UCSF GRCh37 5 96089776 96089776 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 59 136 0 ENST00000341926.3:c.1288C>T p.Pro430Ser p.P430S ENST00000341926 430 Cca/Tca 0 +CASZ1 UCSF GRCh37 1 10720370 10720370 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 40 55 0 ENST00000377022.3:c.729C>T p.Ile243= p.I243= ENST00000377022 NM_001079843.2 243 atC/atT 0 +CATSPER1 UCSF GRCh37 11 65793321 65793321 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 30 71 0 ENST00000312106.5:c.530G>A p.Gly177Glu p.G177E ENST00000312106 NM_053054.3 177 gGg/gAg 0 +CATSPERB UCSF GRCh37 14 92159568 92159568 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 75 196 0 ENST00000256343.3:c.733G>A p.Val245Met p.V245M ENST00000256343 NM_024764.2 245 Gtg/Atg 0 +CBLN1 UCSF GRCh37 16 49315254 49315254 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 32 57 0 ENST00000219197.6:c.123C>T p.Asn41= p.N41= ENST00000219197 NM_004352.3 41 aaC/aaT 0 +CBX6 UCSF GRCh37 22 39262814 39262814 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 34 53 0 ENST00000407418.3:c.639G>A p.Lys213= p.K213= ENST00000407418 213 aaG/aaA 0 +CBY3 UCSF GRCh37 5 179106004 179106004 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 6 10 0 ENST00000376974.4:c.309C>T p.Thr103= p.T103= ENST00000376974 NM_001164444.1 103 acC/acT 0 +CCBP2 UCSF GRCh37 3 42907103 42907103 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 60 116 0 ENST00000273145.2:c.1109C>T p.Ser370Phe p.S370F ENST00000273145 370 tCt/tTt 0 +CCDC108 UCSF GRCh37 2 219870840 219870840 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 32 63 0 ENST00000341552.5:c.4825C>T p.Pro1609Ser p.P1609S ENST00000341552 NM_194302.3 1609 Cca/Tca 0 +CCDC109B UCSF GRCh37 4 110606512 110606512 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 62 143 0 ENST00000394650.4:c.922G>A p.Asp308Asn p.D308N ENST00000394650 NM_017918.4 308 Gac/Aac 0 +CCDC120 UCSF GRCh37 X 48920079 48920079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 16 43 0 ENST00000496529.2:c.130G>A p.Glu44Lys p.E44K ENST00000496529 44 Gag/Aag 0 +CCDC129 UCSF GRCh37 7 31692331 31692331 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 70 179 0 ENST00000407970.3:c.3023C>T p.Thr1008Ile p.T1008I ENST00000407970 NM_194300.3 1008 aCc/aTc 0 +CCDC151 UCSF GRCh37 19 11537720 11537720 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 35 52 0 ENST00000356392.4:c.585G>A p.Ala195= p.A195= ENST00000356392 NM_145045.4 195 gcG/gcA 0 +CCDC160 UCSF GRCh37 X 133379275 133379275 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 76 164 0 ENST00000370809.4:c.445C>T p.Leu149Phe p.L149F ENST00000370809 NM_001101357.1 149 Ctt/Ttt 0 +CCDC17 UCSF GRCh37 1 46087330 46087330 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 10 31 0 ENST00000528266.1:c.1164C>T p.Gly388= p.G388= ENST00000528266 388 ggC/ggT 0 +CCDC19 UCSF GRCh37 1 159847195 159847195 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 93 189 1 ENST00000368099.4:c.1102G>A p.Glu368Lys p.E368K ENST00000368099 NM_012337.2 368 Gag/Aag 0 +CCDC38 UCSF GRCh37 12 96310966 96310966 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 61 137 0 ENST00000344280.3:c.245G>A p.Ser82Asn p.S82N ENST00000344280 NM_182496.2 82 aGt/aAt 0 +CCDC38 UCSF GRCh37 12 96263314 96263314 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 99 195 0 ENST00000344280.3:c.1522C>T p.Gln508Ter p.Q508* ENST00000344280 NM_182496.2 508 Caa/Taa 0 +CCDC40 UCSF GRCh37 17 78073441 78073441 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 49 102 0 ENST00000397545.4:c.3296G>A p.Arg1099His p.R1099H ENST00000397545 NM_017950.3 1099 cGc/cAc 0 +CCDC60 UCSF GRCh37 12 119909884 119909884 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 106 204 0 ENST00000327554.2:c.256C>T p.Leu86Phe p.L86F ENST00000327554 NM_178499.3 86 Ctt/Ttt 0 +CCDC61 UCSF GRCh37 19 46519955 46519955 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 12 32 0 ENST00000595358.1:c.1095G>A p.Gln365= p.Q365= ENST00000595358 NM_001267723.1 365 caG/caA 0 +CCDC67 UCSF GRCh37 11 93122241 93122241 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 54 108 0 ENST00000298050.3:c.991C>T p.Leu331= p.L331= ENST00000298050 NM_181645.3 331 Ctg/Ttg 0 +CCDC69 UCSF GRCh37 5 150565012 150565012 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 79 173 0 ENST00000355417.2:c.586G>A p.Asp196Asn p.D196N ENST00000355417 NM_015621.2 196 Gac/Aac 0 +CCDC7 UCSF GRCh37 10 32740580 32740580 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 112 48 108 0 ENST00000277657.6:c.10G>A p.Val4Ile p.V4I ENST00000277657 NM_001026383.1 4 Gta/Ata 0 +CCDC83 UCSF GRCh37 11 85627205 85627205 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 91 208 0 ENST00000342404.3:c.1009G>A p.Glu337Lys p.E337K ENST00000342404 NM_001286159.1 337 Gaa/Aaa 0 +CCDC88C UCSF GRCh37 14 91766365 91766365 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 16 29 0 ENST00000389857.6:c.3685G>A p.Val1229Ile p.V1229I ENST00000389857 NM_001080414.3 1229 Gtc/Atc 0 +CCDC96 UCSF GRCh37 4 7043007 7043007 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 58 124 0 ENST00000310085.4:c.1659C>T p.Leu553= p.L553= ENST00000310085 NM_153376.2 553 ctC/ctT 0 +CCDC97 UCSF GRCh37 19 41822402 41822402 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 33 69 0 ENST00000269967.3:c.160G>A p.Asp54Asn p.D54N ENST00000269967 NM_052848.1 54 Gac/Aac 0 +CCNB3 UCSF GRCh37 X 50052651 50052651 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 47 140 0 ENST00000276014.7:c.1482G>A p.Lys494= p.K494= ENST00000276014 NM_033031.2 494 aaG/aaA 0 +CCNG1 UCSF GRCh37 5 162866334 162866334 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 85 187 0 ENST00000340828.2:c.72G>A p.Glu24= p.E24= ENST00000340828 NM_004060.3 24 gaG/gaA 0 +CCT6B UCSF GRCh37 17 33269619 33269619 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 32 117 0 ENST00000314144.5:c.769G>A p.Glu257Lys p.E257K ENST00000314144 NM_006584.3 257 Gag/Aag 0 +CCT8 UCSF GRCh37 21 30439086 30439086 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 47 127 0 ENST00000286788.4:c.575C>T p.Pro192Leu p.P192L ENST00000286788 NM_006585.2 192 cCt/cTt 0 +CD109 UCSF GRCh37 6 74519837 74519837 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 23 56 0 ENST00000287097.5:c.3486C>T p.Ile1162= p.I1162= ENST00000287097 1162 atC/atT 0 +CD163 UCSF GRCh37 12 7635298 7635298 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 96 209 0 ENST00000359156.4:c.3188C>T p.Ala1063Val p.A1063V ENST00000359156 NM_004244.5 1063 gCc/gTc 0 +CD163L1 UCSF GRCh37 12 7531826 7531826 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 43 127 0 ENST00000313599.3:c.2119G>A p.Val707Ile p.V707I ENST00000313599 707 Gtc/Atc 0 +CD1A UCSF GRCh37 1 158226682 158226682 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 62 158 0 ENST00000289429.5:c.711G>A p.Trp237Ter p.W237* ENST00000289429 NM_001763.2 237 tgG/tgA 0 +CD300C UCSF GRCh37 17 72537841 72537841 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 60 100 0 ENST00000330793.1:c.562G>A p.Val188Ile p.V188I ENST00000330793 NM_006678.4 188 Gtc/Atc 0 +CD34 UCSF GRCh37 1 208062847 208062847 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 36 97 0 ENST00000310833.7:c.717G>A p.Arg239= p.R239= ENST00000310833 NM_001025109.1 239 agG/agA 0 +CD80 UCSF GRCh37 3 119263481 119263481 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 78 159 0 ENST00000264246.3:c.334G>A p.Gly112Ser p.G112S ENST00000264246 NM_005191.3 112 Ggc/Agc 0 +CD93 UCSF GRCh37 20 23066153 23066153 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 84 147 0 ENST00000246006.4:c.677G>A p.Gly226Glu p.G226E ENST00000246006 NM_012072.3 226 gGg/gAg 0 +CDAN1 UCSF GRCh37 15 43023884 43023884 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 37 89 0 ENST00000356231.3:c.1673C>T p.Pro558Leu p.P558L ENST00000356231 NM_138477.2 558 cCc/cTc 0 +CDC42BPA UCSF GRCh37 1 227221096 227221096 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 60 88 0 ENST00000334218.5:c.3392G>A p.Ser1131Asn p.S1131N ENST00000334218 1131 aGt/aAt 0 +CDC42BPG UCSF GRCh37 11 64602989 64602989 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 58 100 1 ENST00000342711.5:c.1863G>A p.Glu621= p.E621= ENST00000342711 NM_017525.2 621 gaG/gaA 0 +CDC42BPG UCSF GRCh37 11 64597433 64597433 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 25 44 0 ENST00000342711.5:c.3477C>T p.Ala1159= p.A1159= ENST00000342711 NM_017525.2 1159 gcC/gcT 0 +CDH12 UCSF GRCh37 5 21765100 21765100 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 92 172 0 ENST00000382254.1:c.1502C>T p.Ala501Val p.A501V ENST00000382254 NM_004061.3 501 gCc/gTc 0 +CDH13 UCSF GRCh37 16 83065776 83065776 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 48 116 0 ENST00000268613.10:c.460G>A p.Ala154Thr p.A154T ENST00000268613 154 Gca/Aca 0 +CDH15 UCSF GRCh37 16 89245890 89245890 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 39 41 80 0 ENST00000289746.2:c.109G>A p.Ala37Thr p.A37T ENST00000289746 NM_004933.2 37 Gcg/Acg 0 +CDH16 UCSF GRCh37 16 66946301 66946301 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 65 136 0 ENST00000299752.4:c.1392G>A p.Glu464= p.E464= ENST00000299752 NM_001204744.1 464 gaG/gaA 0 +CDH2 UCSF GRCh37 18 25585916 25585916 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 71 155 0 ENST00000269141.3:c.744G>A p.Glu248= p.E248= ENST00000269141 NM_001792.3 248 gaG/gaA 0 +CDH22 UCSF GRCh37 20 44828073 44828073 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 19 26 0 ENST00000372262.3:c.1412C>T p.Ala471Val p.A471V ENST00000372262 471 gCc/gTc 0 +CDH23 UCSF GRCh37 10 73501557 73501557 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 33 70 0 ENST00000224721.6:c.4739C>T p.Ala1580Val p.A1580V ENST00000224721 NM_022124.5 1580 gCc/gTc 0 +CDH23 UCSF GRCh37 10 73574733 73574733 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 16 23 0 ENST00000224721.6:c.9778G>A p.Glu3260Lys p.E3260K ENST00000224721 NM_022124.5 3260 Gag/Aag 0 +CDH24 UCSF GRCh37 14 23523457 23523457 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 75 154 0 ENST00000267383.5:c.865G>A p.Gly289Arg p.G289R ENST00000267383 289 Ggg/Agg 0 +CDH4 UCSF GRCh37 20 59829975 59829975 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 73 117 0 ENST00000360469.5:c.151G>A p.Gly51Arg p.G51R ENST00000360469 NM_001794.3 51 Ggg/Agg 0 +CDH4 UCSF GRCh37 20 60318838 60318838 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 16 18 0 ENST00000360469.5:c.389G>A p.Gly130Glu p.G130E ENST00000360469 NM_001794.3 130 gGa/gAa 0 +CDH6 UCSF GRCh37 5 31317805 31317805 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 67 167 0 ENST00000265071.2:c.1656G>A p.Arg552= p.R552= ENST00000265071 NM_004932.3 552 cgG/cgA 0 +CDHR3 UCSF GRCh37 7 105635292 105635292 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 45 101 0 ENST00000317716.9:c.608+1G>A p.X203_splice ENST00000317716 NM_152750.4 0 +CDK14 UCSF GRCh37 7 90741873 90741873 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 117 98 194 0 ENST00000380050.3:c.1171C>T p.His391Tyr p.H391Y ENST00000380050 NM_001287137.1 391 Cat/Tat 0 +CDK15 UCSF GRCh37 2 202672281 202672281 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 71 209 0 ENST00000450471.2:c.188C>T p.Ala63Val p.A63V ENST00000450471 NM_001261435.1 63 gCc/gTc 0 +CDK15 UCSF GRCh37 2 202755512 202755512 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 39 142 0 ENST00000450471.2:c.1199-14G>A *400* ENST00000450471 NM_001261435.1 0 +CDK20 UCSF GRCh37 9 90582463 90582464 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P10_Rec Untested WXS Illumina HiSeq 10 0 ENST00000325303.8:c.955dup p.His319ProfsTer4 p.H319Pfs*4 ENST00000325303 NM_001039803.2 318 -/C 0 +CDK5R2 UCSF GRCh37 2 219825281 219825281 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 58 98 0 ENST00000302625.4:c.739C>T p.Leu247= p.L247= ENST00000302625 NM_003936.4 247 Ctg/Ttg 0 +CDK5RAP2 UCSF GRCh37 9 123291061 123291061 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 32 88 0 ENST00000349780.4:c.840G>A p.Glu280= p.E280= ENST00000349780 NM_018249.5 280 gaG/gaA 0 +CDKN2A UCSF GRCh37 9 21971017 21971017 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 0 36 38 0 ENST00000304494.5:c.341C>T p.Pro114Leu p.P114L ENST00000304494 NM_000077.4 114 cCc/cTc 0 +CDKN2AIP UCSF GRCh37 4 184367664 184367664 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 84 159 0 ENST00000504169.1:c.827G>A p.Gly276Asp p.G276D ENST00000504169 NM_017632.2 276 gGc/gAc 0 +CDKN2C UCSF GRCh37 1 51436058 51436058 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 64 120 0 ENST00000262662.1:c.18G>A p.Gly6= p.G6= ENST00000262662 6 ggG/ggA 0 +CDRT4 UCSF GRCh37 17 15341337 15341337 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 84 168 0 ENST00000312177.6:c.209C>T p.Ser70Phe p.S70F ENST00000312177 NM_001204477.1 70 tCc/tTc 0 +CDS2 UCSF GRCh37 20 5169773 5169773 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 76 174 0 ENST00000460006.1:c.1042C>T p.Leu348Phe p.L348F ENST00000460006 NM_003818.3 348 Ctc/Ttc 0 +CDS2 UCSF GRCh37 20 5170793 5170793 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 50 107 0 ENST00000460006.1:c.1251G>A p.Arg417= p.R417= ENST00000460006 NM_003818.3 417 cgG/cgA 0 +CEACAM1 UCSF GRCh37 19 43031476 43031476 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 90 231 0 ENST00000161559.6:c.141G>A p.Glu47= p.E47= ENST00000161559 NM_001712.4 47 gaG/gaA 0 +CEBPG UCSF GRCh37 19 33870315 33870315 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 51 125 0 ENST00000284000.4:c.170C>T p.Pro57Leu p.P57L ENST00000284000 NM_001806.3 57 cCc/cTc 0 +CELA3B UCSF GRCh37 1 22304890 22304890 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 49 113 0 ENST00000337107.6:c.72C>T p.Arg24= p.R24= ENST00000337107 NM_007352.2 24 cgC/cgT 0 +CELF3 UCSF GRCh37 1 151679767 151679767 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 8 0 ENST00000290583.4:c.776C>T p.Thr259Ile p.T259I ENST00000290583 NM_001172648.1 259 aCc/aTc 0 +CELF6 UCSF GRCh37 15 72579614 72579614 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 60 127 0 ENST00000287202.5:c.1438C>T p.Pro480Ser p.P480S ENST00000287202 NM_052840.4 480 Cct/Tct 0 +CELSR3 UCSF GRCh37 3 48688385 48688385 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 38 62 0 ENST00000164024.4:c.6310G>A p.Gly2104Ser p.G2104S ENST00000164024 NM_001407.2 2104 Ggc/Agc 0 +CENPF UCSF GRCh37 1 214818138 214818138 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 58 140 0 ENST00000366955.3:c.5225C>T p.Ser1742Phe p.S1742F ENST00000366955 NM_016343.3 1742 tCt/tTt 0 +CENPJ UCSF GRCh37 13 25480951 25480951 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 66 159 0 ENST00000381884.4:c.1225G>A p.Asp409Asn p.D409N ENST00000381884 NM_018451.4 409 Gac/Aac 0 +CENPJ UCSF GRCh37 13 25486880 25486880 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 85 211 0 ENST00000381884.4:c.284C>T p.Thr95Ile p.T95I ENST00000381884 NM_018451.4 95 aCc/aTc 0 +CENPO UCSF GRCh37 2 25040671 25040671 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 45 106 0 ENST00000260662.1:c.899C>T p.Ser300Phe p.S300F ENST00000260662 NM_024322.2 300 tCc/tTc 0 +CEP128 UCSF GRCh37 14 81259283 81259283 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 79 77 160 0 ENST00000281129.3:c.1381T>C p.Tyr461His p.Y461H ENST00000281129 NM_152446.3 461 Tac/Cac 0 +CEP164 UCSF GRCh37 11 117232558 117232558 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 108 172 0 ENST00000278935.3:c.401G>A p.Gly134Asp p.G134D ENST00000278935 NM_014956.4 134 gGt/gAt 0 +CEP250 UCSF GRCh37 20 34086486 34086486 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 55 164 0 ENST00000397527.1:c.3718G>A p.Ala1240Thr p.A1240T ENST00000397527 NM_007186.3 1240 Gca/Aca 0 +CEP290 UCSF GRCh37 12 88508271 88508271 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 65 180 0 ENST00000552810.1:c.1978G>A p.Glu660Lys p.E660K ENST00000552810 NM_025114.3 660 Gaa/Aaa 0 +CEP72 UCSF GRCh37 5 637780 637780 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 41 99 0 ENST00000264935.5:c.1053G>A p.Leu351= p.L351= ENST00000264935 NM_018140.3 351 ttG/ttA 0 +CEP78 UCSF GRCh37 9 80879119 80879119 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 181 85 205 0 ENST00000424347.2:c.1512C>T p.Ala504= p.A504= ENST00000424347 504 gcC/gcT 0 +CERCAM UCSF GRCh37 9 131193495 131193495 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 126 71 136 0 ENST00000372838.4:c.1116C>T p.Leu372= p.L372= ENST00000372838 NM_016174.4 372 ctC/ctT 0 +CFD UCSF GRCh37 19 861762 861762 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 11 10 0 ENST00000327726.6:c.421G>A p.Asp141Asn p.D141N ENST00000327726 NM_001928.2 141 Gac/Aac 0 +CFHR4 UCSF GRCh37 1 196871676 196871676 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 85 202 0 ENST00000367416.2:c.184C>T p.Pro62Ser p.P62S ENST00000367416 NM_001201551.1 62 Cct/Tct 0 +CFTR UCSF GRCh37 7 117120177 117120177 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 31 100 0 ENST00000003084.6:c.29G>A p.Ser10Asn p.S10N ENST00000003084 NM_000492.3 10 aGc/aAc 0 +CGN UCSF GRCh37 1 151491365 151491365 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 53 95 0 ENST00000271636.7:c.370C>T p.Pro124Ser p.P124S ENST00000271636 NM_020770.2 124 Cct/Tct 0 +CGRRF1 UCSF GRCh37 14 55004887 55004887 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 71 142 0 ENST00000216420.7:c.785G>A p.Ser262Asn p.S262N ENST00000216420 NM_006568.2 262 aGt/aAt 0 +CH25H UCSF GRCh37 10 90966981 90966981 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 24 0 ENST00000371852.2:c.69C>T p.Leu23= p.L23= ENST00000371852 NM_003956.3 23 ctC/ctT 0 +CHAF1B UCSF GRCh37 21 37763893 37763893 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 20 27 70 0 ENST00000314103.5:c.304G>A p.Glu102Lys p.E102K ENST00000314103 NM_005441.2 102 Gag/Aag 0 +CHD4 UCSF GRCh37 12 6687042 6687042 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 51 176 0 ENST00000357008.2:c.5270G>A p.Arg1757His p.R1757H ENST00000357008 NM_001273.2 1757 cGc/cAc 0 +CHD6 UCSF GRCh37 20 40112136 40112136 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 62 85 0 ENST00000373233.3:c.2281G>A p.Asp761Asn p.D761N ENST00000373233 NM_032221.4 761 Gat/Aat 0 +CHD6 UCSF GRCh37 20 40080485 40080485 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 60 124 0 ENST00000373233.3:c.3504G>A p.Gln1168= p.Q1168= ENST00000373233 NM_032221.4 1168 caG/caA 0 +CHD7 UCSF GRCh37 8 61754586 61754586 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 64 136 0 ENST00000423902.2:c.4825G>A p.Val1609Met p.V1609M ENST00000423902 NM_017780.3 1609 Gtg/Atg 0 +CHD8 UCSF GRCh37 14 21873407 21873407 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 112 197 0 ENST00000399982.2:c.3268G>A p.Glu1090Lys p.E1090K ENST00000399982 NM_001170629.1 1090 Gag/Aag 0 +CHD9 UCSF GRCh37 16 53190447 53190447 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 158 125 264 0 ENST00000398510.3:c.446C>T p.Ser149Phe p.S149F ENST00000398510 149 tCt/tTt 0 +CHEK2 UCSF GRCh37 22 29091791 29091791 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 62 154 0 ENST00000328354.6:c.1166C>T p.Thr389Ile p.T389I ENST00000328354 NM_007194.3 389 aCc/aTc 0 +CHGB UCSF GRCh37 20 5903741 5903741 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 50 128 0 ENST00000378961.4:c.951C>T p.Ser317= p.S317= ENST00000378961 NM_001819.2 317 agC/agT 0 +CHIA UCSF GRCh37 1 111861263 111861263 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 80 178 0 ENST00000343320.6:c.878C>T p.Pro293Leu p.P293L ENST00000343320 293 cCc/cTc 0 +CHM UCSF GRCh37 X 85133991 85133991 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 23 59 0 ENST00000357749.2:c.1588C>T p.Pro530Ser p.P530S ENST00000357749 NM_000390.2 530 Cca/Tca 0 +CHMP1B UCSF GRCh37 18 11851745 11851745 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 76 140 0 ENST00000526991.2:c.235G>A p.Val79Ile p.V79I ENST00000526991 NM_020412.4 79 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89947281 89947281 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 89 193 0 ENST00000320585.6:c.234G>A p.Lys78= p.K78= ENST00000320585 NM_012124.2 78 aaG/aaA 0 +CHRDL1 UCSF GRCh37 X 109931867 109931868 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 0 ENST00000372045.1:c.922dup p.Ile308AsnfsTer12 p.I308Nfs*12 ENST00000372045 307 -/A 0 +CHRNA10 UCSF GRCh37 11 3690508 3690508 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 31 66 0 ENST00000250699.2:c.280G>A p.Asp94Asn p.D94N ENST00000250699 NM_020402.2 94 Gac/Aac 0 +CHRNA4 UCSF GRCh37 20 61981790 61981790 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 50 97 0 ENST00000370263.4:c.973G>A p.Val325Ile p.V325I ENST00000370263 NM_000744.6 325 Gtc/Atc 0 +CHST8 UCSF GRCh37 19 34263008 34263008 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 22 34 0 ENST00000262622.4:c.315G>A p.Leu105= p.L105= ENST00000262622 NM_022467.3 105 ctG/ctA 0 +CHST9 UCSF GRCh37 18 24496452 24496452 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 163 246 0 ENST00000581714.1:c.1103G>A p.Gly368Glu p.G368E ENST00000581714 368 gGg/gAg 0 +CHST9 UCSF GRCh37 18 24497034 24497034 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 120 120 227 0 ENST00000581714.1:c.521C>T p.Thr174Ile p.T174I ENST00000581714 174 aCc/aTc 0 +CHSY3 UCSF GRCh37 5 129521088 129521088 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 78 199 0 ENST00000305031.4:c.2253C>T p.Asp751= p.D751= ENST00000305031 NM_175856.4 751 gaC/gaT 0 +CHTF18 UCSF GRCh37 16 842965 842965 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 10 11 0 ENST00000262315.9:c.1573-1G>A p.X525_splice ENST00000262315 NM_022092.2 0 +CHTF18 UCSF GRCh37 16 844054 844054 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 31 55 0 ENST00000262315.9:c.1803G>A p.Arg601= p.R601= ENST00000262315 NM_022092.2 601 agG/agA 0 +CIC UCSF GRCh37 19 42790972 42790972 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 21 45 0 ENST00000575354.2:c.117C>T p.Ser39= p.S39= ENST00000575354 NM_015125.3 39 tcC/tcT 0 +CIC UCSF GRCh37 19 42791210 42791210 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 40 64 0 ENST00000575354.2:c.270G>A p.Gly90= p.G90= ENST00000575354 NM_015125.3 90 ggG/ggA 0 +CIRBP UCSF GRCh37 19 1272022 1272022 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 52 90 0 ENST00000320936.5:c.474G>A p.Gly158= p.G158= ENST00000320936 NM_001280.2 158 ggG/ggA 0 +CIZ1 UCSF GRCh37 9 130931423 130931423 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 217 76 178 0 ENST00000372938.5:c.2203G>A p.Asp735Asn p.D735N ENST00000372938 NM_001131016.1 735 Gac/Aac 0 +CKAP5 UCSF GRCh37 11 46818424 46818424 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 111 175 0 ENST00000529230.1:c.1405G>A p.Val469Met p.V469M ENST00000529230 469 Gtg/Atg 0 +CLASP1 UCSF GRCh37 2 122165194 122165194 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 157 121 219 0 ENST00000263710.4:c.2522G>A p.Gly841Asp p.G841D ENST00000263710 NM_015282.2 841 gGc/gAc 0 +CLASRP UCSF GRCh37 19 45563812 45563812 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 18 57 0 ENST00000221455.3:c.790G>A p.Gly264Arg p.G264R ENST00000221455 NM_007056.2 264 Gga/Aga 0 +CLCN6 UCSF GRCh37 1 11896117 11896117 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 31 52 0 ENST00000346436.6:c.1887C>T p.Val629= p.V629= ENST00000346436 NM_001286.3 629 gtC/gtT 0 +CLCN7 UCSF GRCh37 16 1500610 1500610 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 10 17 0 ENST00000382745.4:c.1505G>A p.Cys502Tyr p.C502Y ENST00000382745 NM_001287.5 502 tGc/tAc 0 +CLDN9 UCSF GRCh37 16 3063446 3063446 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 26 56 0 ENST00000445369.2:c.83C>T p.Pro28Leu p.P28L ENST00000445369 NM_020982.3 28 cCc/cTc 0 +CLDN9 UCSF GRCh37 16 3063919 3063919 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 29 58 0 ENST00000445369.2:c.556C>T p.Pro186Ser p.P186S ENST00000445369 NM_020982.3 186 Ccc/Tcc 0 +CLEC16A UCSF GRCh37 16 11272427 11272427 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 53 88 0 ENST00000409790.1:c.3042C>T p.Asp1014= p.D1014= ENST00000409790 NM_015226.2 1014 gaC/gaT 0 +CLEC1B UCSF GRCh37 12 10147756 10147756 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 130 241 0 ENST00000298527.6:c.528G>A p.Ser176= p.S176= ENST00000298527 NM_016509.3 176 tcG/tcA 0 +CLEC4M UCSF GRCh37 19 7828322 7828322 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 87 157 0 ENST00000327325.5:c.90C>T p.Asp30= p.D30= ENST00000327325 NM_001144909.1 30 gaC/gaT 0 +CLK4 UCSF GRCh37 5 178043923 178043923 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 37 89 0 ENST00000316308.4:c.502G>A p.Gly168Arg p.G168R ENST00000316308 NM_020666.2 168 Gga/Aga 0 +CLPB UCSF GRCh37 11 72005736 72005736 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 48 100 0 ENST00000294053.3:c.1578G>A p.Gly526= p.G526= ENST00000294053 NM_001258394.1 526 ggG/ggA 0 +CLPP UCSF GRCh37 19 6364519 6364519 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 19 24 0 ENST00000245816.4:c.424C>T p.Pro142Ser p.P142S ENST00000245816 NM_006012.2 142 Ccg/Tcg 0 +CLPTM1L UCSF GRCh37 5 1344507 1344507 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 20 73 0 ENST00000320895.5:c.222C>T p.Val74= p.V74= ENST00000320895 NM_030782.3 74 gtC/gtT 0 +CLU UCSF GRCh37 8 27462723 27462723 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 41 87 0 ENST00000316403.10:c.547G>A p.Ala183Thr p.A183T ENST00000316403 183 Gcg/Acg 0 +CLVS1 UCSF GRCh37 8 62212733 62212733 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 60 128 0 ENST00000325897.4:c.347C>T p.Pro116Leu p.P116L ENST00000325897 NM_173519.2 116 cCc/cTc 0 +CLVS2 UCSF GRCh37 6 123319199 123319199 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 77 150 0 ENST00000275162.5:c.277G>A p.Asp93Asn p.D93N ENST00000275162 NM_001010852.3 93 Gac/Aac 0 +CMIP UCSF GRCh37 16 81703821 81703821 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 59 97 0 ENST00000537098.3:c.900G>A p.Gly300= p.G300= ENST00000537098 NM_198390.2 300 ggG/ggA 0 +CMYA5 UCSF GRCh37 5 79026452 79026452 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 137 147 275 0 ENST00000446378.2:c.1864G>A p.Glu622Lys p.E622K ENST00000446378 NM_153610.3 622 Gaa/Aaa 0 +CMYA5 UCSF GRCh37 5 79029525 79029525 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 125 115 192 0 ENST00000446378.2:c.4937G>A p.Gly1646Asp p.G1646D ENST00000446378 NM_153610.3 1646 gGt/gAt 0 +CMYA5 UCSF GRCh37 5 79034504 79034504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 138 132 232 0 ENST00000446378.2:c.9916G>A p.Glu3306Lys p.E3306K ENST00000446378 NM_153610.3 3306 Gaa/Aaa 0 +CNGA1 UCSF GRCh37 4 47939393 47939393 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 134 126 236 0 ENST00000358519.4:c.1118C>T p.Ser373Phe p.S373F ENST00000358519 373 tCt/tTt 0 +CNGA1 UCSF GRCh37 4 47942856 47942856 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 63 164 0 ENST00000358519.4:c.588C>T p.Tyr196= p.Y196= ENST00000358519 196 taC/taT 0 +CNGB1 UCSF GRCh37 16 57937766 57937766 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 25 63 0 ENST00000251102.8:c.2754G>A p.Lys918= p.K918= ENST00000251102 NM_001297.4 918 aaG/aaA 0 +CNKSR2 UCSF GRCh37 X 21627446 21627446 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 87 187 0 ENST00000379510.3:c.2403C>T p.Ser801= p.S801= ENST00000379510 NM_014927.3 801 tcC/tcT 0 +CNN2 UCSF GRCh37 19 1037819 1037819 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 65 127 0 ENST00000263097.4:c.850C>T p.Pro284Ser p.P284S ENST00000263097 NM_004368.2 284 Ccc/Tcc 0 +CNPY4 UCSF GRCh37 7 99717410 99717410 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 37 86 0 ENST00000262932.3:c.43G>A p.Ala15Thr p.A15T ENST00000262932 NM_152755.1 15 Gcc/Acc 0 +CNR1 UCSF GRCh37 6 88853924 88853924 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 102 154 0 ENST00000369499.2:c.1070G>A p.Gly357Asp p.G357D ENST00000369499 357 gGc/gAc 0 +CNTFR UCSF GRCh37 9 34557523 34557523 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 33 67 0 ENST00000351266.4:c.604+1G>A p.X202_splice ENST00000351266 NM_001842.4 0 +CNTN1 UCSF GRCh37 12 41330588 41330588 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 102 182 0 ENST00000347616.1:c.991C>T p.Pro331Ser p.P331S ENST00000347616 331 Cct/Tct 0 +CNTN2 UCSF GRCh37 1 205038637 205038637 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 22 41 0 ENST00000331830.4:c.2144C>T p.Ser715Leu p.S715L ENST00000331830 NM_005076.3 715 tCa/tTa 0 +CNTN2 UCSF GRCh37 1 205039621 205039621 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 14 44 0 ENST00000331830.4:c.2499G>A p.Trp833Ter p.W833* ENST00000331830 NM_005076.3 833 tgG/tgA 0 +COBRA1 UCSF GRCh37 9 140151381 140151381 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 50 118 0 ENST00000343053.4:c.472G>A p.Gly158Arg p.G158R ENST00000343053 NM_015456.3 158 Ggg/Agg 0 +COIL UCSF GRCh37 17 55028356 55028356 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 62 113 0 ENST00000240316.4:c.247G>A p.Val83Ile p.V83I ENST00000240316 NM_004645.2 83 Gtt/Att 0 +COL12A1 UCSF GRCh37 6 75898105 75898105 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 73 183 0 ENST00000322507.8:c.970C>T p.Leu324Phe p.L324F ENST00000322507 NM_004370.5 324 Ctt/Ttt 0 +COL14A1 UCSF GRCh37 8 121215987 121215987 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 36 85 0 ENST00000297848.3:c.917C>T p.Ala306Val p.A306V ENST00000297848 NM_021110.2 306 gCc/gTc 0 +COL14A1 UCSF GRCh37 8 121313017 121313017 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 304 89 204 0 ENST00000297848.3:c.4361C>T p.Ser1454Phe p.S1454F ENST00000297848 NM_021110.2 1454 tCt/tTt 0 +COL15A1 UCSF GRCh37 9 101810250 101810250 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 37 58 0 ENST00000375001.3:c.2761G>A p.Gly921Ser p.G921S ENST00000375001 NM_001855.4 921 Ggt/Agt 0 +COL19A1 UCSF GRCh37 6 70608851 70608851 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 35 120 0 ENST00000322773.4:c.103C>T p.Pro35Ser p.P35S ENST00000322773 NM_001858.4 35 Cct/Tct 0 +COL19A1 UCSF GRCh37 6 70859755 70859755 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 100 154 1 ENST00000322773.4:c.1942C>T p.Leu648Phe p.L648F ENST00000322773 NM_001858.4 648 Ctc/Ttc 0 +COL1A1 UCSF GRCh37 17 48263779 48263779 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 91 170 0 ENST00000225964.5:c.3904C>T p.Pro1302Ser p.P1302S ENST00000225964 NM_000088.3 1302 Ccc/Tcc 0 +COL1A1 UCSF GRCh37 17 48270368 48270368 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 21 43 0 ENST00000225964.5:c.1808C>T p.Pro603Leu p.P603L ENST00000225964 NM_000088.3 603 cCc/cTc 0 +COL1A2 UCSF GRCh37 7 94052288 94052288 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 82 180 0 ENST00000297268.6:c.2423G>A p.Gly808Asp p.G808D ENST00000297268 NM_000089.3 808 gGt/gAt 0 +COL1A2 UCSF GRCh37 7 94054440 94054440 + synonymous_variant Silent SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 30 14 95 0 ENST00000297268.6:c.2685T>C p.Gly895= p.G895= ENST00000297268 NM_000089.3 895 ggT/ggC 0 +COL22A1 UCSF GRCh37 8 139838948 139838948 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 255 51 110 1 ENST00000303045.6:c.922G>A p.Glu308Lys p.E308K ENST00000303045 NM_152888.1 308 Gaa/Aaa 0 +COL22A1 UCSF GRCh37 8 139611048 139611048 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 158 37 112 0 ENST00000303045.6:c.4279C>T p.Leu1427= p.L1427= ENST00000303045 NM_152888.1 1427 Ctg/Ttg 0 +COL23A1 UCSF GRCh37 5 177669372 177669372 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 26 69 0 ENST00000390654.3:c.1464G>A p.Glu488= p.E488= ENST00000390654 NM_173465.3 488 gaG/gaA 0 +COL23A1 UCSF GRCh37 5 177690266 177690266 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 21 26 47 0 ENST00000390654.3:c.582C>T p.Ala194= p.A194= ENST00000390654 NM_173465.3 194 gcC/gcT 0 +COL24A1 UCSF GRCh37 1 86200550 86200550 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 76 174 0 ENST00000370571.2:c.4880G>A p.Arg1627Lys p.R1627K ENST00000370571 NM_152890.5 1627 aGg/aAg 0 +COL27A1 UCSF GRCh37 9 116930191 116930191 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 43 77 0 ENST00000356083.3:c.356G>A p.Ser119Asn p.S119N ENST00000356083 NM_032888.2 119 aGc/aAc 0 +COL28A1 UCSF GRCh37 7 7493129 7493129 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 61 145 0 ENST00000399429.3:c.1382G>A p.Gly461Asp p.G461D ENST00000399429 NM_001037763.2 461 gGt/gAt 0 +COL28A1 UCSF GRCh37 7 7572463 7572463 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 94 201 0 ENST00000399429.3:c.44C>T p.Ala15Val p.A15V ENST00000399429 NM_001037763.2 15 gCg/gTg 0 +COL2A1 UCSF GRCh37 12 48377895 48377895 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 7 23 0 ENST00000380518.3:c.1916G>A p.Gly639Asp p.G639D ENST00000380518 NM_033150.2 639 gGt/gAt 0 +COL3A1 UCSF GRCh37 2 189849927 189849927 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 58 154 0 ENST00000304636.3:c.287C>T p.Thr96Ile p.T96I ENST00000304636 NM_000090.3 96 aCt/aTt 0 +COL4A6 UCSF GRCh37 X 107408120 107408120 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 32 55 0 ENST00000372216.4:c.3960G>A p.Glu1320= p.E1320= ENST00000372216 NM_001847.2 1320 gaG/gaA 0 +COL6A3 UCSF GRCh37 2 238261999 238261999 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 22 65 0 ENST00000295550.4:c.6675G>A p.Gly2225= p.G2225= ENST00000295550 NM_004369.3 2225 ggG/ggA 0 +COL6A5 UCSF GRCh37 3 130159572 130159572 + synonymous_variant,NMD_transcript_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 85 213 0 ENST00000312481.7:c.6390C>T p.Tyr2130= p.Y2130= ENST00000312481 2130 taC/taT 0 +COL6A6 UCSF GRCh37 3 130293243 130293243 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 98 175 0 ENST00000358511.6:c.3421G>A p.Asp1141Asn p.D1141N ENST00000358511 NM_001102608.1 1141 Gat/Aat 0 +COL9A1 UCSF GRCh37 6 70972963 70972963 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 21 64 0 ENST00000357250.6:c.1379G>A p.Gly460Glu p.G460E ENST00000357250 NM_001851.4 460 gGa/gAa 0 +COLEC12 UCSF GRCh37 18 346738 346738 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 64 129 0 ENST00000400256.3:c.884G>A p.Gly295Asp p.G295D ENST00000400256 NM_130386.2 295 gGt/gAt 0 +COQ10B UCSF GRCh37 2 198334869 198334869 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 24 91 0 ENST00000263960.2:c.523C>T p.Pro175Ser p.P175S ENST00000263960 NM_025147.3 175 Cca/Tca 0 +COQ2 UCSF GRCh37 4 84205914 84205914 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 18 31 0 ENST00000311469.4:c.154C>T p.Leu52= p.L52= ENST00000311469 NM_015697.7 52 Ctg/Ttg 0 +CORO2A UCSF GRCh37 9 100897104 100897104 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 25 43 0 ENST00000343933.5:c.452C>T p.Ala151Val p.A151V ENST00000343933 NM_003389.3 151 gCt/gTt 0 +COX4I1 UCSF GRCh37 16 85840402 85840402 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 66 120 0 ENST00000253452.2:c.432G>A p.Arg144= p.R144= ENST00000253452 NM_001861.3 144 agG/agA 0 +CPAMD8 UCSF GRCh37 19 17014386 17014386 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0021 P10_Rec Untested WXS Illumina HiSeq 84 63 126 0 ENST00000443236.1:c.4596C>T p.Gly1532= p.G1532= ENST00000443236 NM_015692.2 1532 ggC/ggT 0 +CPNE4 UCSF GRCh37 3 131268852 131268852 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 67 141 0 ENST00000429747.1:c.1241C>T p.Ala414Val p.A414V ENST00000429747 NM_130808.1 414 gCc/gTc 0 +CPOX UCSF GRCh37 3 98311991 98311991 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 17 20 0 ENST00000264193.2:c.358G>A p.Glu120Lys p.E120K ENST00000264193 NM_000097.5 120 Gag/Aag 0 +CPPED1 UCSF GRCh37 16 12798798 12798798 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 57 103 0 ENST00000381774.4:c.398C>T p.Thr133Ile p.T133I ENST00000381774 NM_018340.2 133 aCc/aTc 0 +CPS1 UCSF GRCh37 2 211465437 211465437 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 75 191 0 ENST00000233072.5:c.1707+1G>A p.X569_splice ENST00000233072 NM_001875.4 0 +CPSF4 UCSF GRCh37 7 99051688 99051688 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 78 139 0 ENST00000292476.5:c.670G>A p.Val224Ile p.V224I ENST00000292476 224 Gtc/Atc 0 +CRAMP1L UCSF GRCh37 16 1706298 1706298 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 18 30 0 ENST00000293925.5:c.1540C>T p.Pro514Ser p.P514S ENST00000293925 NM_020825.3 514 Ccc/Tcc 0 +CRB2 UCSF GRCh37 9 126132611 126132611 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 31 80 0 ENST00000373631.3:c.1279C>T p.Pro427Ser p.P427S ENST00000373631 NM_173689.5 427 Cca/Tca 0 +CREB3 UCSF GRCh37 9 35736396 35736396 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 95 127 0 ENST00000353704.2:c.789C>T p.Ser263= p.S263= ENST00000353704 NM_006368.4 263 tcC/tcT 0 +CREB3L4 UCSF GRCh37 1 153941022 153941022 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 58 105 0 ENST00000271889.4:c.21C>T p.Asp7= p.D7= ENST00000271889 7 gaC/gaT 0 +CRISPLD1 UCSF GRCh37 8 75941713 75941713 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 34 119 0 ENST00000262207.4:c.1412C>T p.Thr471Ile p.T471I ENST00000262207 NM_031461.5 471 aCc/aTc 0 +CRTAM UCSF GRCh37 11 122726526 122726526 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 45 173 0 ENST00000227348.4:c.614G>A p.Gly205Glu p.G205E ENST00000227348 NM_019604.2 205 gGg/gAg 0 +CRTC2 UCSF GRCh37 1 153923901 153923901 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 19 35 0 ENST00000368633.1:c.1239C>T p.Ala413= p.A413= ENST00000368633 NM_181715.2 413 gcC/gcT 0 +CRTC3 UCSF GRCh37 15 91162994 91162994 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 37 116 0 ENST00000268184.6:c.721C>T p.Pro241Ser p.P241S ENST00000268184 241 Cct/Tct 0 +CRYM UCSF GRCh37 16 21286866 21286866 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 42 78 1 ENST00000219599.3:c.374C>T p.Ala125Val p.A125V ENST00000219599 NM_001888.3 125 gCc/gTc 0 +CRYZL1 UCSF GRCh37 21 34989027 34989027 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 64 134 0 ENST00000381554.3:c.247G>A p.Asp83Asn p.D83N ENST00000381554 NM_145858.2 83 Gat/Aat 0 +CSF1 UCSF GRCh37 1 110456983 110456983 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 40 83 0 ENST00000329608.6:c.142C>T p.Leu48= p.L48= ENST00000329608 NM_000757.5 48 Ctg/Ttg 0 +CSF3R UCSF GRCh37 1 36941258 36941258 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 25 65 0 ENST00000361632.4:c.81G>A p.Gly27= p.G27= ENST00000361632 27 ggG/ggA 0 +CSMD1 UCSF GRCh37 8 3566007 3566008 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 0 ENST00000537824.1:c.938dup p.Ala314GlyfsTer3 p.A314Gfs*3 ENST00000537824 NM_033225.5 313 aag/aAag 0 +CSMD2 UCSF GRCh37 1 34164377 34164377 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 72 129 0 ENST00000241312.4:c.3781G>A p.Asp1261Asn p.D1261N ENST00000241312 1261 Gac/Aac 0 +CSMD3 UCSF GRCh37 8 113275893 113275893 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 173 50 110 0 ENST00000297405.5:c.9837G>A p.Trp3279Ter p.W3279* ENST00000297405 NM_198123.1 3279 tgG/tgA 0 +CSNK1G1 UCSF GRCh37 15 64472608 64472608 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 51 102 0 ENST00000303052.7:c.1153G>A p.Gly385Arg p.G385R ENST00000303052 NM_022048.3 385 Gga/Aga 0 +CSPG4 UCSF GRCh37 15 75968078 75968078 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 50 81 0 ENST00000308508.5:c.6782C>T p.Thr2261Ile p.T2261I ENST00000308508 NM_001897.4 2261 aCt/aTt 0 +CST1 UCSF GRCh37 20 23731336 23731336 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 54 108 0 ENST00000304749.2:c.168C>T p.Asn56= p.N56= ENST00000304749 NM_001898.2 56 aaC/aaT 0 +CSTF3 UCSF GRCh37 11 33118465 33118465 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 58 154 0 ENST00000323959.4:c.1188G>A p.Met396Ile p.M396I ENST00000323959 NM_001326.2 396 atG/atA 0 +CTAG2 UCSF GRCh37 X 153880590 153880590 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 63 102 0 ENST00000247306.4:c.585G>A p.Gly195= p.G195= ENST00000247306 NM_020994.3 195 ggG/ggA 0 +CTAGE1 UCSF GRCh37 18 19996271 19996271 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 132 89 199 0 ENST00000391403.2:c.1504G>A p.Ala502Thr p.A502T ENST00000391403 NM_172241.2 502 Gct/Act 0 +CTAGE6P UCSF GRCh37 7 143453428 143453428 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 165 79 316 0 ENST00000470691.2:c.1324G>A p.Glu442Lys p.E442K ENST00000470691 NM_178561.4 442 Gaa/Aaa 0 +CTBP2 UCSF GRCh37 10 126716248 126716248 + intron_variant Intron SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 36 48 0 ENST00000337195.5:c.58+11318G>A *20* ENST00000337195 NM_001329.2 0 +CTC1 UCSF GRCh37 17 8138531 8138531 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 52 85 0 ENST00000315684.8:c.1279G>A p.Gly427Ser p.G427S ENST00000315684 NM_025099.5 427 Ggc/Agc 0 +CTNNA3 UCSF GRCh37 10 68940213 68940213 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 71 182 0 ENST00000433211.2:c.909C>T p.Arg303= p.R303= ENST00000433211 NM_013266.2 303 cgC/cgT 0 +CTPS2 UCSF GRCh37 X 16638419 16638419 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 85 203 0 ENST00000359276.4:c.1430G>A p.Arg477Lys p.R477K ENST00000359276 NM_175859.1 477 aGa/aAa 0 +CTSC UCSF GRCh37 11 88042421 88042421 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 34 121 0 ENST00000227266.5:c.551C>T p.Ser184Phe p.S184F ENST00000227266 NM_001814.4 184 tCt/tTt 0 +CTTNBP2 UCSF GRCh37 7 117364699 117364699 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 69 74 142 0 ENST00000160373.3:c.4349G>A p.Gly1450Glu p.G1450E ENST00000160373 NM_033427.2 1450 gGa/gAa 0 +CTTNBP2NL UCSF GRCh37 1 112999829 112999829 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 90 169 0 ENST00000271277.6:c.1715C>T p.Pro572Leu p.P572L ENST00000271277 NM_018704.2 572 cCc/cTc 0 +CTU2 UCSF GRCh37 16 88780121 88780121 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 73 108 0 ENST00000453996.2:c.940G>A p.Glu314Lys p.E314K ENST00000453996 NM_001012759.1 314 Gag/Aag 0 +CUBN UCSF GRCh37 10 17032352 17032352 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 197 65 178 0 ENST00000377833.4:c.4331G>A p.Cys1444Tyr p.C1444Y ENST00000377833 NM_001081.3 1444 tGc/tAc 0 +CUL2 UCSF GRCh37 10 35299354 35299354 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 53 111 0 ENST00000374748.1:c.2123G>A p.Arg708Lys p.R708K ENST00000374748 708 aGa/aAa 0 +CUL7 UCSF GRCh37 6 43017703 43017703 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 75 204 0 ENST00000265348.3:c.1567G>A p.Glu523Lys p.E523K ENST00000265348 523 Gag/Aag 0 +CUL7 UCSF GRCh37 6 43013324 43013324 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 46 73 0 ENST00000265348.3:c.2862+1G>A p.X954_splice ENST00000265348 0 +CUL9 UCSF GRCh37 6 43156415 43156415 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 54 97 0 ENST00000252050.4:c.2142G>A p.Glu714= p.E714= ENST00000252050 NM_015089.2 714 gaG/gaA 0 +CUX1 UCSF GRCh37 7 101882782 101882782 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 60 144 0 ENST00000292535.7:c.3805C>T p.Pro1269Ser p.P1269S ENST00000292535 NM_181552.3 1269 Ccg/Tcg 0 +CUX2 UCSF GRCh37 12 111760369 111760369 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 10 25 0 ENST00000261726.6:c.2911C>T p.Pro971Ser p.P971S ENST00000261726 NM_015267.3 971 Cct/Tct 0 +CXCL1 UCSF GRCh37 4 74735288 74735288 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 32 58 0 ENST00000395761.3:c.100+1G>A p.X34_splice ENST00000395761 NM_001511.3 0 +CXCR5 UCSF GRCh37 11 118764684 118764684 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 50 80 0 ENST00000292174.4:c.431C>T p.Ala144Val p.A144V ENST00000292174 NM_001716.4 144 gCc/gTc 0 +CXXC1 UCSF GRCh37 18 47812480 47812480 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 68 126 0 ENST00000285106.6:c.371C>T p.Ser124Leu p.S124L ENST00000285106 NM_001101654.1 124 tCa/tTa 0 +CYB561 UCSF GRCh37 17 61511818 61511818 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 16 25 0 ENST00000360793.3:c.701C>T p.Ala234Val p.A234V ENST00000360793 NM_001915.3 234 gCc/gTc 0 +CYB5D1 UCSF GRCh37 17 7761957 7761957 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 54 108 0 ENST00000332439.4:c.271C>T p.Leu91= p.L91= ENST00000332439 NM_144607.4 91 Ctg/Ttg 0 +CYBASC3 UCSF GRCh37 11 61121326 61121326 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 42 74 0 ENST00000294072.4:c.323G>A p.Gly108Glu p.G108E ENST00000294072 NM_153611.4 108 gGa/gAa 0 +CYFIP1 UCSF GRCh37 15 22993045 22993045 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 18 58 0 ENST00000313077.7:c.2932C>T p.His978Tyr p.H978Y ENST00000313077 NM_014608.2 978 Cac/Tac 0 +CYHR1 UCSF GRCh37 8 145676143 145676143 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 8 16 0 ENST00000438911.2:c.708C>T p.Phe236= p.F236= ENST00000438911 NM_138496.1 236 ttC/ttT 0 +CYP1A2 UCSF GRCh37 15 75042111 75042111 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 101 205 0 ENST00000343932.4:c.32C>T p.Ala11Val p.A11V ENST00000343932 NM_000761.3 11 gCc/gTc 0 +CYP1A2 UCSF GRCh37 15 75042559 75042559 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 95 174 0 ENST00000343932.4:c.480C>T p.Tyr160= p.Y160= ENST00000343932 NM_000761.3 160 taC/taT 0 +CYP27C1 UCSF GRCh37 2 127961147 127961147 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 70 139 0 ENST00000335247.7:c.-22G>A p.X8_splice ENST00000335247 NM_001001665.3 0 +CYP2C19 UCSF GRCh37 10 96540357 96540357 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 89 229 0 ENST00000371321.3:c.583C>T p.Leu195Phe p.L195F ENST00000371321 NM_000769.1 195 Ctt/Ttt 0 +CYP2J2 UCSF GRCh37 1 60366771 60366771 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 46 127 0 ENST00000371204.3:c.1196C>T p.Thr399Ile p.T399I ENST00000371204 NM_000775.2 399 aCc/aTc 0 +CYP2S1 UCSF GRCh37 19 41703712 41703712 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 31 84 0 ENST00000310054.4:c.372G>A p.Trp124Ter p.W124* ENST00000310054 NM_030622.6 124 tgG/tgA 0 +CYP4F22 UCSF GRCh37 19 15636309 15636309 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 27 49 0 ENST00000269703.3:c.162C>T p.Arg54= p.R54= ENST00000269703 NM_173483.3 54 cgC/cgT 0 +CYTH1 UCSF GRCh37 17 76696430 76696430 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 22 51 0 ENST00000361101.4:c.533G>A p.Gly178Asp p.G178D ENST00000361101 NM_017456.2 178 gGc/gAc 0 +DAAM1 UCSF GRCh37 14 59821883 59821883 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 62 168 0 ENST00000395125.1:c.2387C>T p.Ala796Val p.A796V ENST00000395125 NM_014992.2 796 gCa/gTa 0 +DAB2 UCSF GRCh37 5 39382822 39382822 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 68 159 0 ENST00000320816.6:c.1239G>A p.Lys413= p.K413= ENST00000320816 NM_001343.3 413 aaG/aaA 0 +DACT1 UCSF GRCh37 14 59113147 59113147 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 20 29 0 ENST00000335867.4:c.1806G>A p.Arg602= p.R602= ENST00000335867 602 agG/agA 0 +DAGLA UCSF GRCh37 11 61505189 61505189 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 39 82 0 ENST00000257215.5:c.1545C>T p.Phe515= p.F515= ENST00000257215 NM_006133.2 515 ttC/ttT 0 +DAK UCSF GRCh37 11 61105600 61105600 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 42 61 0 ENST00000394900.3:c.191C>T p.Ala64Val p.A64V ENST00000394900 NM_015533.3 64 gCt/gTt 0 +DALRD3 UCSF GRCh37 3 49053920 49053920 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 1 41 86 0 ENST00000341949.4:c.1088G>A p.Gly363Asp p.G363D ENST00000341949 NM_001009996.2 363 gGt/gAt 0 +DAP3 UCSF GRCh37 1 155686916 155686916 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 87 187 1 ENST00000343043.3:c.165C>T p.Asp55= p.D55= ENST00000343043 NM_033657.2 55 gaC/gaT 0 +DAXX UCSF GRCh37 6 33289341 33289341 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 83 83 180 0 ENST00000266000.6:c.211C>T p.Leu71Phe p.L71F ENST00000266000 71 Ctt/Ttt 0 +DBC1 UCSF GRCh37 9 122075558 122075558 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 53 119 0 ENST00000265922.3:c.76G>A p.Glu26Lys p.E26K ENST00000265922 NM_014618.2 26 Gaa/Aaa 0 +DCAF4L1 UCSF GRCh37 4 41984755 41984755 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 75 149 0 ENST00000333141.5:c.946G>A p.Ala316Thr p.A316T ENST00000333141 NM_001029955.3 316 Gcc/Acc 0 +DCBLD2 UCSF GRCh37 3 98538238 98538238 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 58 158 0 ENST00000326840.6:c.895G>A p.Glu299Lys p.E299K ENST00000326840 NM_080927.3 299 Gag/Aag 0 +DCC UCSF GRCh37 18 50985745 50985745 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 99 211 0 ENST00000442544.2:c.3536C>T p.Pro1179Leu p.P1179L ENST00000442544 NM_005215.3 1179 cCc/cTc 0 +DCHS1 UCSF GRCh37 11 6662142 6662143 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P10_Rec Untested WXS Illumina HiSeq 8 0 ENST00000299441.3:c.703dup p.Arg235ProfsTer16 p.R235Pfs*16 ENST00000299441 NM_003737.2 234 -/C 0 +DCHS2 UCSF GRCh37 4 155156320 155156320 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 69 157 0 ENST00000357232.4:c.8119C>T p.Gln2707Ter p.Q2707* ENST00000357232 NM_017639.3 2707 Caa/Taa 0 +DCN UCSF GRCh37 12 91572319 91572319 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 77 137 0 ENST00000052754.5:c.11C>T p.Thr4Ile p.T4I ENST00000052754 NM_001920.3 4 aCt/aTt 0 +DCP1B UCSF GRCh37 12 2055379 2055379 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 44 111 0 ENST00000280665.6:c.1847C>T p.Thr616Ile p.T616I ENST00000280665 NM_152640.3 616 aCt/aTt 0 +DDAH1 UCSF GRCh37 1 85816190 85816190 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 94 213 0 ENST00000284031.8:c.505G>A p.Ala169Thr p.A169T ENST00000284031 NM_012137.3 169 Gca/Aca 0 +DDB2 UCSF GRCh37 11 47256340 47256340 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 67 122 0 ENST00000256996.4:c.735G>A p.Val245= p.V245= ENST00000256996 NM_000107.2 245 gtG/gtA 0 +DDR1 UCSF GRCh37 6 30862416 30862416 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 57 141 0 ENST00000324771.8:c.1481C>T p.Pro494Leu p.P494L ENST00000324771 494 cCc/cTc 0 +DDR1 UCSF GRCh37 6 30860850 30860850 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 39 80 0 ENST00000324771.8:c.1105G>A p.Val369Met p.V369M ENST00000324771 369 Gtg/Atg 0 +DDX11 UCSF GRCh37 12 31256518 31256518 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 62 78 0 ENST00000545668.1:c.2539C>T p.His847Tyr p.H847Y ENST00000545668 NM_001257144.1 847 Cat/Tat 0 +DDX11 UCSF GRCh37 12 31250914 31250914 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 18 131 0 ENST00000545668.1:c.1858G>A p.Gly620Arg p.G620R ENST00000545668 NM_001257144.1 620 Ggg/Agg 0 +DDX23 UCSF GRCh37 12 49230351 49230351 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 72 118 0 ENST00000308025.3:c.1236+1G>A p.X412_splice ENST00000308025 NM_004818.2 0 +DDX27 UCSF GRCh37 20 47836064 47836064 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 27 49 0 ENST00000371764.4:c.172G>A p.Asp58Asn p.D58N ENST00000371764 NM_017895.7 58 Gac/Aac 0 +DDX4 UCSF GRCh37 5 55063757 55063757 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 57 144 0 ENST00000505374.1:c.383C>T p.Ser128Phe p.S128F ENST00000505374 NM_024415.2 128 tCc/tTc 0 +DDX53 UCSF GRCh37 X 23018198 23018198 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 18 46 0 ENST00000327968.5:c.24G>A p.Trp8Ter p.W8* ENST00000327968 NM_182699.3 8 tgG/tgA 0 +DDX59 UCSF GRCh37 1 200635267 200635267 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 92 208 0 ENST00000331314.6:c.602C>T p.Pro201Leu p.P201L ENST00000331314 NM_001031725.4 201 cCc/cTc 0 +DDX6 UCSF GRCh37 11 118656891 118656891 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 136 119 231 0 ENST00000526070.2:c.70C>T p.Pro24Ser p.P24S ENST00000526070 NM_001257191.1 24 Cct/Tct 0 +DECR1 UCSF GRCh37 8 91054975 91054975 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 279 80 194 0 ENST00000220764.2:c.685G>A p.Gly229Ser p.G229S ENST00000220764 NM_001359.1 229 Ggt/Agt 0 +DEFB132 UCSF GRCh37 20 239761 239761 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 74 124 0 ENST00000382376.3:c.102C>T p.Tyr34= p.Y34= ENST00000382376 NM_207469.2 34 taC/taT 0 +DENND1B UCSF GRCh37 1 197510100 197510100 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 102 223 0 ENST00000391979.2:c.316C>T p.Leu106= p.L106= ENST00000391979 NM_001195215.1 106 Cta/Tta 0 +DENND2D UCSF GRCh37 1 111731408 111731408 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 81 128 0 ENST00000357640.4:c.1015G>A p.Val339Ile p.V339I ENST00000357640 NM_024901.4 339 Gtt/Att 0 +DEPDC5 UCSF GRCh37 22 32302255 32302255 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 3 68 96 0 ENST00000400246.1:c.4523G>A p.Gly1508Glu p.G1508E ENST00000400246 1508 gGa/gAa 0 +DEPDC5 UCSF GRCh37 22 32179972 32179972 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 80 181 0 ENST00000400246.1:c.562+1G>A p.X188_splice ENST00000400246 0 +DES UCSF GRCh37 2 220286152 220286152 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 62 108 0 ENST00000373960.3:c.1114G>A p.Glu372Lys p.E372K ENST00000373960 NM_001927.3 372 Gag/Aag 0 +DET1 UCSF GRCh37 15 89074632 89074632 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 114 194 0 ENST00000268148.8:c.305G>A p.Gly102Glu p.G102E ENST00000268148 NM_001144074.1 102 gGa/gAa 0 +DFNA5 UCSF GRCh37 7 24745895 24745895 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 37 69 0 ENST00000342947.3:c.1091G>A p.Gly364Glu p.G364E ENST00000342947 NM_004403.2 364 gGg/gAg 0 +DFNA5 UCSF GRCh37 7 24738789 24738789 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 43 96 0 ENST00000342947.3:c.1347G>A p.Gln449= p.Q449= ENST00000342947 NM_004403.2 449 caG/caA 0 +DFNB31 UCSF GRCh37 9 117170265 117170265 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 12 22 0 ENST00000362057.3:c.1660G>A p.Val554Ile p.V554I ENST00000362057 NM_001173425.1 554 Gtc/Atc 0 +DGCR14 UCSF GRCh37 22 19124860 19124860 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 78 156 0 ENST00000252137.6:c.1011C>T p.Asp337= p.D337= ENST00000252137 NM_022719.2 337 gaC/gaT 0 +DGCR8 UCSF GRCh37 22 20073698 20073698 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 63 116 1 ENST00000351989.3:c.212G>A p.Gly71Glu p.G71E ENST00000351989 NM_022720.6 71 gGa/gAa 0 +DHDDS UCSF GRCh37 1 26795537 26795537 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 64 115 0 ENST00000236342.7:c.917G>A p.Arg306Gln p.R306Q ENST00000236342 306 cGg/cAg 0 +DHDH UCSF GRCh37 19 49442716 49442716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 80 182 0 ENST00000221403.2:c.377C>T p.Thr126Ile p.T126I ENST00000221403 NM_014475.3 126 aCc/aTc 0 +DHRS12 UCSF GRCh37 13 52373669 52373669 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 66 131 0 ENST00000444610.2:c.190+1G>A p.X64_splice ENST00000444610 NM_001270424.1 0 +DHX29 UCSF GRCh37 5 54579056 54579056 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 41 101 0 ENST00000251636.5:c.1940G>A p.Gly647Asp p.G647D ENST00000251636 NM_019030.2 647 gGc/gAc 0 +DIDO1 UCSF GRCh37 20 61513186 61513186 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 77 162 0 ENST00000266070.4:c.4122G>A p.Lys1374= p.K1374= ENST00000266070 NM_033081.2 1374 aaG/aaA 0 +DIO3 UCSF GRCh37 14 102028251 102028251 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 50 74 0 ENST00000510508.4:c.418G>A p.Val140Met p.V140M ENST00000510508 140 Gtg/Atg 0 +DIP2C UCSF GRCh37 10 323417 323417 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 52 114 0 ENST00000280886.6:c.4519C>T p.Leu1507= p.L1507= ENST00000280886 NM_014974.2 1507 Ctg/Ttg 0 +DLD UCSF GRCh37 7 107555952 107555952 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 55 127 0 ENST00000205402.5:c.686G>A p.Gly229Asp p.G229D ENST00000205402 NM_000108.3 229 gGt/gAt 0 +DLEC1 UCSF GRCh37 3 38126876 38126876 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 54 154 0 ENST00000308059.6:c.1373C>T p.Thr458Ile p.T458I ENST00000308059 458 aCc/aTc 0 +DLG4 UCSF GRCh37 17 7122158 7122158 + upstream_gene_variant 5'Flank SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 27 92 0 ENST00000399506 0 +DLG5 UCSF GRCh37 10 79567601 79567601 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 59 112 0 ENST00000372391.2:c.4749G>A p.Glu1583= p.E1583= ENST00000372391 NM_004747.3 1583 gaG/gaA 0 +DLL3 UCSF GRCh37 19 39998575 39998575 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 38 104 0 ENST00000205143.4:c.1779C>T p.Pro593= p.P593= ENST00000205143 NM_016941.3 593 ccC/ccT 0 +DMGDH UCSF GRCh37 5 78326661 78326661 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 42 88 0 ENST00000255189.3:c.1678C>T p.Pro560Ser p.P560S ENST00000255189 NM_013391.3 560 Cca/Tca 0 +DMRTA2 UCSF GRCh37 1 50885107 50885107 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 38 57 1 ENST00000404795.3:c.859G>A p.Glu287Lys p.E287K ENST00000404795 NM_032110.2 287 Gaa/Aaa 0 +DMXL2 UCSF GRCh37 15 51772750 51772750 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 116 89 181 0 ENST00000251076.5:c.6553G>A p.Glu2185Lys p.E2185K ENST00000251076 NM_015263.3 2185 Gaa/Aaa 0 +DMXL2 UCSF GRCh37 15 51860709 51860709 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 24 62 0 ENST00000251076.5:c.260G>A p.Gly87Asp p.G87D ENST00000251076 NM_015263.3 87 gGc/gAc 0 +DNAH10 UCSF GRCh37 12 124408889 124408889 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 82 151 0 ENST00000409039.3:c.11322G>A p.Trp3774Ter p.W3774* ENST00000409039 NM_207437.3 3774 tgG/tgA 0 +DNAH17 UCSF GRCh37 17 76420176 76420176 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 48 112 0 ENST00000389840.5:c.13269C>T p.Thr4423= p.T4423= ENST00000389840 4423 acC/acT 0 +DNAH17 UCSF GRCh37 17 76488815 76488815 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 52 129 0 ENST00000389840.5:c.6399C>T p.Asn2133= p.N2133= ENST00000389840 2133 aaC/aaT 0 +DNAH2 UCSF GRCh37 17 7700504 7700504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 67 173 0 ENST00000389173.2:c.7874G>A p.Gly2625Asp p.G2625D ENST00000389173 NM_020877.2 2625 gGc/gAc 0 +DNAH5 UCSF GRCh37 5 13814842 13814842 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 59 149 0 ENST00000265104.4:c.7102C>T p.Pro2368Ser p.P2368S ENST00000265104 NM_001369.2 2368 Ccc/Tcc 0 +DNAH5 UCSF GRCh37 5 13714642 13714642 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 41 101 0 ENST00000265104.4:c.12997C>T p.Leu4333= p.L4333= ENST00000265104 NM_001369.2 4333 Ctg/Ttg 0 +DNAH7 UCSF GRCh37 2 196852860 196852860 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 55 151 0 ENST00000312428.6:c.1447G>A p.Glu483Lys p.E483K ENST00000312428 NM_018897.2 483 Gag/Aag 0 +DNAH7 UCSF GRCh37 2 196726495 196726495 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 48 139 0 ENST00000312428.6:c.7682C>T p.Thr2561Ile p.T2561I ENST00000312428 NM_018897.2 2561 aCc/aTc 0 +DNAH8 UCSF GRCh37 6 38994423 38994423 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 56 113 0 ENST00000359357.3:c.13165G>A p.Glu4389Lys p.E4389K ENST00000359357 4389 Gag/Aag 0 +DNAI1 UCSF GRCh37 9 34491538 34491538 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 51 103 0 ENST00000242317.4:c.667G>A p.Ala223Thr p.A223T ENST00000242317 NM_012144.3 223 Gcc/Acc 0 +DNAJC16 UCSF GRCh37 1 15855742 15855742 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 73 157 1 ENST00000375847.3:c.142G>A p.Ala48Thr p.A48T ENST00000375847 NM_015291.2 48 Gct/Act 0 +DNAJC17 UCSF GRCh37 15 41071767 41071767 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 44 76 0 ENST00000220496.4:c.183G>A p.Glu61= p.E61= ENST00000220496 NM_018163.2 61 gaG/gaA 0 +DNAJC19 UCSF GRCh37 3 180705975 180705975 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 66 177 1 ENST00000382564.2:c.46G>A p.Gly16Arg p.G16R ENST00000382564 NM_145261.3 16 Gga/Aga 0 +DNHD1 UCSF GRCh37 11 6524079 6524079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 74 130 0 ENST00000254579.6:c.843G>A p.Met281Ile p.M281I ENST00000254579 NM_144666.2 281 atG/atA 0 +DNMT3A UCSF GRCh37 2 25458593 25458593 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 58 63 127 0 ENST00000264709.3:c.2580G>A p.Trp860Ter p.W860* ENST00000264709 NM_175629.2 860 tgG/tgA 0 +DNMT3A UCSF GRCh37 2 25470532 25470532 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 43 43 87 0 ENST00000264709.3:c.942G>A p.Trp314Ter p.W314* ENST00000264709 NM_175629.2 314 tgG/tgA 0 +DNMT3L UCSF GRCh37 21 45668988 45668988 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 13 27 0 ENST00000270172.3:c.916C>T p.Pro306Ser p.P306S ENST00000270172 NM_013369.3 306 Cca/Tca 0 +DOC2A UCSF GRCh37 16 30017765 30017765 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 72 135 0 ENST00000350119.4:c.1026C>T p.Asp342= p.D342= ENST00000350119 NM_003586.2 342 gaC/gaT 0 +DOCK10 UCSF GRCh37 2 225781483 225781483 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 63 133 0 ENST00000258390.7:c.262G>A p.Asp88Asn p.D88N ENST00000258390 NM_014689.2 88 Gat/Aat 0 +DOCK3 UCSF GRCh37 3 51378721 51378721 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 42 77 0 ENST00000266037.9:c.3820C>T p.Pro1274Ser p.P1274S ENST00000266037 NM_004947.4 1274 Cca/Tca 0 +DOCK7 UCSF GRCh37 1 62962166 62962166 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 42 129 0 ENST00000340370.5:c.4674C>T p.Asn1558= p.N1558= ENST00000340370 NM_033407.3 1558 aaC/aaT 0 +DOK2 UCSF GRCh37 8 21771109 21771109 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 56 145 0 ENST00000276420.4:c.4G>A p.Gly2Arg p.G2R ENST00000276420 NM_003974.2 2 Gga/Aga 0 +DOK7 UCSF GRCh37 4 3494641 3494641 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 16 12 0 ENST00000340083.5:c.928G>A p.Ala310Thr p.A310T ENST00000340083 NM_173660.4 310 Gcc/Acc 0 +DOLK UCSF GRCh37 9 131708637 131708637 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 197 84 168 0 ENST00000372586.3:c.946C>T p.Leu316= p.L316= ENST00000372586 NM_014908.3 316 Ctg/Ttg 0 +DOPEY1 UCSF GRCh37 6 83848015 83848015 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0014 P10_Rec Untested WXS Illumina HiSeq 110 110 266 0 ENST00000349129.2:c.4254C>T p.Leu1418= p.L1418= ENST00000349129 NM_015018.3 1418 ctC/ctT 0 +DOPEY2 UCSF GRCh37 21 37612210 37612210 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 15 23 0 ENST00000399151.3:c.3024C>T p.Thr1008= p.T1008= ENST00000399151 NM_005128.2 1008 acC/acT 0 +DPCD UCSF GRCh37 10 103368682 103368682 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 68 160 0 ENST00000370151.4:c.495C>T p.Thr165= p.T165= ENST00000370151 NM_015448.1 165 acC/acT 0 +DPF1 UCSF GRCh37 19 38714783 38714783 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 11 8 0 ENST00000420980.2:c.81G>A p.Lys27= p.K27= ENST00000420980 NM_004647.2 27 aaG/aaA 0 +DPF1 UCSF GRCh37 19 38713076 38713076 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 62 106 0 ENST00000420980.2:c.300C>T p.Tyr100= p.Y100= ENST00000420980 NM_004647.2 100 taC/taT 0 +DPF2 UCSF GRCh37 11 65113205 65113205 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 62 115 0 ENST00000528416.1:c.706G>A p.Glu236Lys p.E236K ENST00000528416 NM_006268.4 236 Gag/Aag 0 +DPH2 UCSF GRCh37 1 44438150 44438150 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 53 99 0 ENST00000255108.3:c.1409C>T p.Thr470Ile p.T470I ENST00000255108 NM_001384.4 470 aCa/aTa 0 +DPH5 UCSF GRCh37 1 101479318 101479318 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 78 178 0 ENST00000370109.3:c.317G>A p.Arg106Lys p.R106K ENST00000370109 NM_001077395.1 106 aGa/aAa 0 +DPYSL2 UCSF GRCh37 8 26513222 26513222 + stop_retained_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 49 87 0 ENST00000311151.5:c.1719G>A p.Ter573= p.*573= ENST00000311151 NM_001386.5 573 taG/taA 0 +DRD1 UCSF GRCh37 5 174869048 174869048 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 83 153 0 ENST00000393752.2:c.1055C>T p.Pro352Leu p.P352L ENST00000393752 NM_000794.3 352 cCt/cTt 0 +DRD3 UCSF GRCh37 3 113847651 113847651 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 117 218 0 ENST00000460779.1:c.1115G>A p.Gly372Asp p.G372D ENST00000460779 NM_001282563.1 372 gGc/gAc 0 +DSC3 UCSF GRCh37 18 28611002 28611002 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 33 116 0 ENST00000360428.4:c.291G>A p.Trp97Ter p.W97* ENST00000360428 NM_001941.3 97 tgG/tgA 0 +DSCAM UCSF GRCh37 21 41385166 41385166 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 48 88 0 ENST00000400454.1:c.5834C>T p.Pro1945Leu p.P1945L ENST00000400454 NM_001271534.1 1945 cCc/cTc 0 +DSCAM UCSF GRCh37 21 41452089 41452089 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 44 147 0 ENST00000400454.1:c.4410C>T p.Thr1470= p.T1470= ENST00000400454 NM_001271534.1 1470 acC/acT 0 +DSCAML1 UCSF GRCh37 11 117303857 117303857 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 26 49 0 ENST00000321322.6:c.5203C>T p.Leu1735= p.L1735= ENST00000321322 NM_020693.2 1735 Ctg/Ttg 0 +DSE UCSF GRCh37 6 116757597 116757597 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 92 181 0 ENST00000331677.3:c.1966C>T p.Pro656Ser p.P656S ENST00000331677 656 Ccc/Tcc 0 +DSEL UCSF GRCh37 18 65179666 65179666 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 58 145 0 ENST00000310045.7:c.2210G>A p.Arg737Lys p.R737K ENST00000310045 NM_032160.2 737 aGa/aAa 0 +DST UCSF GRCh37 6 56380398 56380398 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 92 146 0 ENST00000244364.6:c.10557G>A p.Gln3519= p.Q3519= ENST00000244364 NM_015548.4 3519 caG/caA 0 +DUOX2 UCSF GRCh37 15 45401797 45401797 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 49 145 0 ENST00000603300.1:c.1159G>A p.Val387Met p.V387M ENST00000603300 NM_014080.4 387 Gtg/Atg 0 +DUOX2 UCSF GRCh37 15 45392393 45392393 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 40 103 0 ENST00000603300.1:c.3039G>A p.Glu1013= p.E1013= ENST00000603300 NM_014080.4 1013 gaG/gaA 0 +DUPD1 UCSF GRCh37 10 76818240 76818240 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 44 104 0 ENST00000338487.5:c.33G>A p.Lys11= p.K11= ENST00000338487 NM_001003892.1 11 aaG/aaA 0 +DUSP11 UCSF GRCh37 2 74007117 74007117 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 51 86 0 ENST00000272444.3:c.126G>A p.Arg42= p.R42= ENST00000272444 NM_003584.2 42 cgG/cgA 0 +DYNC1I1 UCSF GRCh37 7 95705396 95705396 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 61 136 0 ENST00000324972.6:c.1588G>A p.Asp530Asn p.D530N ENST00000324972 NM_004411.4 530 Gac/Aac 0 +DYNC2H1 UCSF GRCh37 11 103006301 103006301 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 32 106 0 ENST00000375735.2:c.2283C>T p.Tyr761= p.Y761= ENST00000375735 NM_001080463.1 761 taC/taT 0 +DYRK1A UCSF GRCh37 21 38877737 38877737 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 103 217 0 ENST00000398960.2:c.1391C>T p.Pro464Leu p.P464L ENST00000398960 NM_001396.3 464 cCc/cTc 0 +DYRK1A UCSF GRCh37 21 38884582 38884582 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 76 181 0 ENST00000398960.2:c.2040C>T p.Tyr680= p.Y680= ENST00000398960 NM_001396.3 680 taC/taT 0 +DYSF UCSF GRCh37 2 71891506 71891506 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 44 81 0 ENST00000258104.3:c.4995C>T p.Asp1665= p.D1665= ENST00000258104 NM_003494.3 1665 gaC/gaT 0 +DYTN UCSF GRCh37 2 207557959 207557959 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 79 167 0 ENST00000452335.2:c.920G>A p.Arg307Lys p.R307K ENST00000452335 NM_001093730.1 307 aGa/aAa 0 +DZIP3 UCSF GRCh37 3 108335494 108335494 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 63 159 0 ENST00000361582.3:c.365G>A p.Gly122Asp p.G122D ENST00000361582 NM_014648.3 122 gGc/gAc 0 +E2F5 UCSF GRCh37 8 86119660 86119660 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 27 91 0 ENST00000416274.2:c.551G>A p.Gly184Asp p.G184D ENST00000416274 NM_001083588.1 184 gGt/gAt 0 +ECE1 UCSF GRCh37 1 21582624 21582624 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 34 86 0 ENST00000374893.6:c.836C>T p.Thr279Ile p.T279I ENST00000374893 NM_001397.2 279 aCc/aTc 0 +ECE1 UCSF GRCh37 1 21599352 21599352 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 49 87 0 ENST00000374893.6:c.333C>T p.Ile111= p.I111= ENST00000374893 NM_001397.2 111 atC/atT 0 +ECHDC1 UCSF GRCh37 6 127611073 127611073 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 111 237 0 ENST00000531967.1:c.865G>A p.Val289Ile p.V289I ENST00000531967 NM_001139510.1 289 Gtt/Att 0 +ECM2 UCSF GRCh37 9 95277190 95277190 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 150 60 131 0 ENST00000344604.5:c.777G>A p.Arg259= p.R259= ENST00000344604 NM_001393.3 259 agG/agA 0 +ECSCR UCSF GRCh37 5 138842242 138842242 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 8 14 0 ENST00000515823.1:c.14G>A p.Gly5Glu p.G5E ENST00000515823 NM_001077693.2 5 gGa/gAa 0 +EDF1 UCSF GRCh37 9 139760663 139760663 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 14 24 0 ENST00000224073.1:c.48C>T p.Gly16= p.G16= ENST00000224073 NM_001281298.1 16 ggC/ggT 0 +EDIL3 UCSF GRCh37 5 83356203 83356203 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 58 117 0 ENST00000296591.5:c.1053G>A p.Trp351Ter p.W351* ENST00000296591 NM_005711.4 351 tgG/tgA 0 +EDN3 UCSF GRCh37 20 57897444 57897445 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 0 ENST00000337938.2:c.565dup p.Thr189AsnfsTer10 p.T189Nfs*10 ENST00000337938 NM_207034.1 187 gaa/gaAa 0 +EEF1G UCSF GRCh37 11 62340136 62340136 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 83 181 0 ENST00000329251.4:c.91G>A p.Val31Met p.V31M ENST00000329251 NM_001404.4 31 Gtg/Atg 0 +EEPD1 UCSF GRCh37 7 36324420 36324420 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 55 98 0 ENST00000242108.4:c.1167G>A p.Gly389= p.G389= ENST00000242108 NM_030636.2 389 ggG/ggA 0 +EFHA1 UCSF GRCh37 13 22141047 22141047 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 2 37 94 0 ENST00000382374.4:c.247C>T p.Pro83Ser p.P83S ENST00000382374 NM_152726.2 83 Ccg/Tcg 0 +EFHC1 UCSF GRCh37 6 52317622 52317622 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 111 228 0 ENST00000371068.5:c.710C>T p.Thr237Ile p.T237I ENST00000371068 NM_018100.3 237 aCc/aTc 0 +EFNB3 UCSF GRCh37 17 7611322 7611322 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 53 111 0 ENST00000226091.2:c.169C>T p.Arg57Trp p.R57W ENST00000226091 NM_001406.3 57 Cgg/Tgg 0 +EFR3B UCSF GRCh37 2 25377127 25377127 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 56 108 0 ENST00000403714.3:c.2372C>T p.Thr791Ile p.T791I ENST00000403714 NM_014971.1 791 aCc/aTc 0 +EHD4 UCSF GRCh37 15 42201974 42201974 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 118 191 0 ENST00000220325.4:c.1012C>T p.Leu338= p.L338= ENST00000220325 NM_139265.3 338 Cta/Tta 0 +EHD4 UCSF GRCh37 15 42211800 42211800 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 40 66 0 ENST00000220325.4:c.532C>T p.Leu178= p.L178= ENST00000220325 NM_139265.3 178 Ctg/Ttg 0 +EID2B UCSF GRCh37 19 40023266 40023266 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 27 53 0 ENST00000326282.4:c.177G>A p.Arg59= p.R59= ENST00000326282 NM_152361.1 59 cgG/cgA 0 +EIF2B4 UCSF GRCh37 2 27591954 27591954 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 49 104 0 ENST00000347454.4:c.337G>A p.Ala113Thr p.A113T ENST00000347454 NM_015636.3 113 Gcc/Acc 0 +EIF2C2 UCSF GRCh37 8 141551327 141551327 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 18 41 0 ENST00000220592.5:c.1970C>T p.Thr657Met p.T657M ENST00000220592 NM_012154.3 657 aCg/aTg 0 +EIF2C2 UCSF GRCh37 8 141554325 141554325 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 355 89 149 0 ENST00000220592.5:c.1826C>T p.Pro609Leu p.P609L ENST00000220592 NM_012154.3 609 cCc/cTc 0 +EIF3H UCSF GRCh37 8 117671106 117671106 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 179 51 173 0 ENST00000521861.1:c.403G>A p.Asp135Asn p.D135N ENST00000521861 NM_003756.2 135 Gac/Aac 0 +EIF4G1 UCSF GRCh37 3 184039886 184039886 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 47 110 0 ENST00000346169.2:c.1514C>T p.Thr505Ile p.T505I ENST00000346169 NM_198241.2 505 aCt/aTt 0 +EIF5B UCSF GRCh37 2 99977841 99977841 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 105 198 0 ENST00000289371.6:c.477G>A p.Lys159= p.K159= ENST00000289371 NM_015904.3 159 aaG/aaA 0 +ELP3 UCSF GRCh37 8 27995380 27995380 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 97 0 ENST00000256398.8:c.1072C>T p.Pro358Ser p.P358S ENST00000256398 NM_018091.5 358 Cca/Tca 0 +EML5 UCSF GRCh37 14 89171891 89171891 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 77 140 0 ENST00000380664.5:c.1867C>T p.Leu623= p.L623= ENST00000380664 623 Ctg/Ttg 0 +ENDOV UCSF GRCh37 17 78389561 78389561 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 12 33 0 ENST00000518137.1:c.168G>A p.Val56= p.V56= ENST00000518137 NM_173627.3 56 gtG/gtA 0 +ENO1 UCSF GRCh37 1 8927255 8927255 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 67 174 0 ENST00000234590.4:c.365G>A p.Gly122Asp p.G122D ENST00000234590 NM_001428.3 122 gGt/gAt 0 +ENPEP UCSF GRCh37 4 111470765 111470765 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 81 176 0 ENST00000265162.5:c.2307G>A p.Glu769= p.E769= ENST00000265162 NM_001977.3 769 gaG/gaA 0 +EOMES UCSF GRCh37 3 27758589 27758589 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 91 192 0 ENST00000295743.4:c.2033G>A p.Gly678Glu p.G678E ENST00000295743 NM_005442.3 678 gGg/gAg 0 +EPAS1 UCSF GRCh37 2 46607851 46607851 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 57 132 0 ENST00000263734.3:c.2040G>A p.Lys680= p.K680= ENST00000263734 NM_001430.4 680 aaG/aaA 0 +EPB41L4B UCSF GRCh37 9 111965953 111965953 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 150 73 158 1 ENST00000374566.3:c.1936G>A p.Ala646Thr p.A646T ENST00000374566 NM_019114.3 646 Gct/Act 0 +EPC2 UCSF GRCh37 2 149402614 149402614 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 7 18 0 ENST00000258484.6:c.28G>A p.Ala10Thr p.A10T ENST00000258484 NM_015630.3 10 Gcg/Acg 0 +EPG5 UCSF GRCh37 18 43460146 43460146 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 47 80 0 ENST00000282041.5:c.5561C>T p.Thr1854Ile p.T1854I ENST00000282041 NM_020964.2 1854 aCt/aTt 0 +EPHA10 UCSF GRCh37 1 38184480 38184480 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 17 29 0 ENST00000373048.4:c.2765C>T p.Thr922Ile p.T922I ENST00000373048 NM_001099439.1 922 aCc/aTc 0 +EPHA10 UCSF GRCh37 1 38227159 38227159 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 7 77 0 ENST00000373048.4:c.768C>T p.Cys256= p.C256= ENST00000373048 NM_001099439.1 256 tgC/tgT 0 +EPHA4 UCSF GRCh37 2 222428779 222428779 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 85 189 0 ENST00000281821.2:c.495G>A p.Lys165= p.K165= ENST00000281821 NM_004438.3 165 aaG/aaA 0 +EPHA6 UCSF GRCh37 3 96945264 96945264 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 109 201 0 ENST00000389672.5:c.1270+1G>A p.X424_splice ENST00000389672 NM_001080448.2 0 +EPHA6 UCSF GRCh37 3 97198209 97198209 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 61 113 0 ENST00000389672.5:c.2074+1G>A p.X692_splice ENST00000389672 NM_001080448.2 0 +EPHA8 UCSF GRCh37 1 22923809 22923809 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 40 103 0 ENST00000166244.3:c.1770C>T p.Pro590= p.P590= ENST00000166244 NM_020526.3 590 ccC/ccT 0 +EPHB3 UCSF GRCh37 3 184290929 184290929 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 44 61 0 ENST00000330394.2:c.821G>A p.Gly274Asp p.G274D ENST00000330394 NM_004443.3 274 gGc/gAc 0 +EPHB4 UCSF GRCh37 7 100401105 100401105 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 12 21 0 ENST00000358173.3:c.2942G>A p.Gly981Glu p.G981E ENST00000358173 NM_004444.4 981 gGa/gAa 0 +EPN1 UCSF GRCh37 19 56204063 56204063 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 12 40 0 ENST00000270460.6:c.1078G>A p.Val360Ile p.V360I ENST00000270460 NM_001130072.1 360 Gtc/Atc 0 +EPPK1 UCSF GRCh37 8 144945735 144945735 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 19 23 0 ENST00000525985.1:c.1687C>T p.Leu563= p.L563= ENST00000525985 NM_031308.2 563 Ctg/Ttg 0 +ERAP2 UCSF GRCh37 5 96232164 96232164 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 68 145 0 ENST00000437043.3:c.1327C>T p.Pro443Ser p.P443S ENST00000437043 NM_001130140.1 443 Ccg/Tcg 0 +ERBB2IP UCSF GRCh37 5 65349627 65349627 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 47 111 0 ENST00000284037.5:c.2481G>A p.Glu827= p.E827= ENST00000284037 NM_001253697.1 827 gaG/gaA 0 +ERBB3 UCSF GRCh37 12 56490602 56490602 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 77 129 0 ENST00000267101.3:c.2246G>A p.Gly749Glu p.G749E ENST00000267101 NM_001982.3 749 gGa/gAa 0 +ERBB4 UCSF GRCh37 2 212589815 212589815 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 61 137 0 ENST00000342788.4:c.727G>A p.Asp243Asn p.D243N ENST00000342788 NM_005235.2 243 Gac/Aac 0 +ERCC1 UCSF GRCh37 19 45923624 45923624 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 19 54 0 ENST00000300853.3:c.383C>T p.Pro128Leu p.P128L ENST00000300853 NM_001983.3 128 cCc/cTc 0 +ERF UCSF GRCh37 19 42754626 42754626 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 46 89 0 ENST00000222329.4:c.114G>A p.Arg38= p.R38= ENST00000222329 NM_006494.2 38 cgG/cgA 0 +ERF UCSF GRCh37 19 42753580 42753580 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 19 25 0 ENST00000222329.4:c.684C>T p.Asp228= p.D228= ENST00000222329 NM_006494.2 228 gaC/gaT 0 +ERG UCSF GRCh37 21 39763610 39763610 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 41 118 0 ENST00000398919.2:c.863C>T p.Pro288Leu p.P288L ENST00000398919 NM_001243428.1 288 cCc/cTc 0 +ERICH1 UCSF GRCh37 8 623456 623456 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 97 164 0 ENST00000262109.7:c.896C>T p.Ala299Val p.A299V ENST00000262109 NM_207332.1 299 gCg/gTg 0 +ERMAP UCSF GRCh37 1 43300733 43300733 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 67 154 0 ENST00000372514.3:c.458C>T p.Pro153Leu p.P153L ENST00000372514 NM_018538.3 153 cCc/cTc 0 +ERN2 UCSF GRCh37 16 23714018 23714018 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0022 P10_Rec Untested WXS Illumina HiSeq 69 63 125 0 ENST00000256797.4:c.1004C>T p.Thr335Met p.T335M ENST00000256797 NM_033266.3 335 aCg/aTg 0 +ESD UCSF GRCh37 13 47356811 47356811 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 74 188 0 ENST00000378720.3:c.372C>T p.Val124= p.V124= ENST00000378720 NM_001984.1 124 gtC/gtT 0 +ESPL1 UCSF GRCh37 12 53680219 53680219 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 69 184 0 ENST00000257934.4:c.3699G>A p.Glu1233= p.E1233= ENST00000257934 NM_012291.4 1233 gaG/gaA 0 +ESPN UCSF GRCh37 1 6488326 6488326 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 69 105 0 ENST00000377828.1:c.335C>T p.Ala112Val p.A112V ENST00000377828 NM_031475.2 112 gCc/gTc 0 +ESPN UCSF GRCh37 1 6512025 6512025 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 22 31 0 ENST00000377828.1:c.2194G>A p.Val732Met p.V732M ENST00000377828 NM_031475.2 732 Gtg/Atg 0 +ESR1 UCSF GRCh37 6 152265335 152265335 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 76 120 0 ENST00000206249.3:c.788G>A p.Arg263Lys p.R263K ENST00000206249 NM_000125.3 263 aGa/aAa 0 +ESR1 UCSF GRCh37 6 152265501 152265501 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 94 189 0 ENST00000206249.3:c.954C>T p.Ala318= p.A318= ENST00000206249 NM_000125.3 318 gcC/gcT 0 +ETAA1 UCSF GRCh37 2 67632437 67632437 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 46 111 0 ENST00000272342.5:c.2623C>T p.Leu875Phe p.L875F ENST00000272342 NM_019002.3 875 Ctt/Ttt 0 +ETFB UCSF GRCh37 19 51853620 51853620 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 10 45 0 ENST00000309244.4:c.401C>T p.Thr134Ile p.T134I ENST00000309244 NM_001985.2 134 aCa/aTa 0 +ETFDH UCSF GRCh37 4 159606372 159606372 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 84 172 0 ENST00000511912.1:c.606+1G>A p.X202_splice ENST00000511912 NM_004453.2 0 +ETS1 UCSF GRCh37 11 128354799 128354799 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 79 187 0 ENST00000319397.6:c.649G>A p.Asp217Asn p.D217N ENST00000319397 NM_005238.3 217 Gac/Aac 0 +ETS1 UCSF GRCh37 11 128350152 128350152 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 28 76 0 ENST00000319397.6:c.925C>T p.Arg309Trp p.R309W ENST00000319397 NM_005238.3 309 Cgg/Tgg 0 +ETV6 UCSF GRCh37 12 12022684 12022684 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 69 148 0 ENST00000396373.4:c.790C>T p.Arg264Cys p.R264C ENST00000396373 NM_001987.4 264 Cgc/Tgc 0 +EVC UCSF GRCh37 4 5785446 5785446 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 44 94 0 ENST00000264956.6:c.1731G>A p.Arg577= p.R577= ENST00000264956 NM_153717.2 577 agG/agA 0 +EVC2 UCSF GRCh37 4 5624454 5624454 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 48 90 0 ENST00000344408.5:c.2311C>T p.Leu771Phe p.L771F ENST00000344408 NM_147127.4 771 Ctc/Ttc 0 +EVI5 UCSF GRCh37 1 93167697 93167697 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 30 57 0 ENST00000370331.1:c.771+1G>A p.X257_splice ENST00000370331 NM_005665.4 0 +EVPL UCSF GRCh37 17 74019607 74019607 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 47 79 0 ENST00000301607.3:c.327C>T p.His109= p.H109= ENST00000301607 NM_001988.2 109 caC/caT 0 +EXOC4 UCSF GRCh37 7 132959927 132959927 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 55 122 0 ENST00000253861.4:c.276+1G>A p.X92_splice ENST00000253861 NM_021807.3 0 +EXOSC4 UCSF GRCh37 8 145135346 145135346 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 210 33 97 0 ENST00000316052.5:c.580G>A p.Gly194Arg p.G194R ENST00000316052 NM_019037.2 194 Gga/Aga 0 +EXT1 UCSF GRCh37 8 119122868 119122868 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 266 88 180 0 ENST00000378204.2:c.418G>A p.Gly140Ser p.G140S ENST00000378204 NM_000127.2 140 Ggc/Agc 0 +EYA2 UCSF GRCh37 20 45801378 45801378 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 63 127 0 ENST00000327619.5:c.1061G>A p.Gly354Asp p.G354D ENST00000327619 NM_005244.4 354 gGc/gAc 0 +F11 UCSF GRCh37 4 187205281 187205281 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 56 149 0 ENST00000403665.2:c.1171G>A p.Gly391Arg p.G391R ENST00000403665 NM_000128.3 391 Gga/Aga 0 +F8 UCSF GRCh37 X 154066018 154066018 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 35 80 0 ENST00000360256.4:c.6910G>A p.Gly2304Arg p.G2304R ENST00000360256 NM_000132.3 2304 Gga/Aga 0 +FADS2 UCSF GRCh37 11 61624933 61624933 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 77 97 0 ENST00000278840.4:c.813G>A p.Pro271= p.P271= ENST00000278840 NM_004265.3 271 ccG/ccA 0 +FAHD2B UCSF GRCh37 2 97750012 97750012 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 47 85 0 ENST00000272610.3:c.688C>T p.Pro230Ser p.P230S ENST00000272610 NM_199336.1 230 Cca/Tca 0 +FAM102A UCSF GRCh37 9 130716147 130716147 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 52 103 0 ENST00000373095.1:c.204G>A p.Lys68= p.K68= ENST00000373095 NM_001035254.2 68 aaG/aaA 0 +FAM110A UCSF GRCh37 20 826100 826100 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 23 34 0 ENST00000246100.3:c.653G>A p.Gly218Glu p.G218E ENST00000246100 NM_207121.3 218 gGg/gAg 0 +FAM111A UCSF GRCh37 11 58920368 58920368 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 97 195 0 ENST00000361723.3:c.1227G>A p.Arg409= p.R409= ENST00000361723 NM_198847.2 409 agG/agA 0 +FAM129B UCSF GRCh37 9 130269465 130269465 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 20 30 0 ENST00000373312.3:c.1900C>T p.Pro634Ser p.P634S ENST00000373312 NM_022833.2 634 Ccc/Tcc 0 +FAM129B UCSF GRCh37 9 130289497 130289497 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 34 55 0 ENST00000373312.3:c.291G>A p.Gly97= p.G97= ENST00000373312 NM_022833.2 97 ggG/ggA 0 +FAM135A UCSF GRCh37 6 71235693 71235693 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 55 114 0 ENST00000370479.3:c.2267C>T p.Ser756Leu p.S756L ENST00000370479 756 tCa/tTa 0 +FAM13A UCSF GRCh37 4 89912297 89912297 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 46 91 0 ENST00000264344.5:c.432C>T p.Gly144= p.G144= ENST00000264344 NM_014883.3 144 ggC/ggT 0 +FAM149A UCSF GRCh37 4 187075793 187075793 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 40 98 0 ENST00000356371.5:c.1256+1G>A p.X419_splice ENST00000356371 0 +FAM150A UCSF GRCh37 8 53451020 53451020 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 31 85 0 ENST00000358543.4:c.373C>T p.Leu125= p.L125= ENST00000358543 NM_207413.3 125 Ctg/Ttg 0 +FAM163A UCSF GRCh37 1 179783118 179783118 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 36 85 0 ENST00000341785.4:c.298C>T p.Pro100Ser p.P100S ENST00000341785 NM_173509.2 100 Cca/Tca 0 +FAM171B UCSF GRCh37 2 187626962 187626962 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 81 213 0 ENST00000304698.5:c.1893C>T p.Val631= p.V631= ENST00000304698 NM_177454.3 631 gtC/gtT 0 +FAM177A1 UCSF GRCh37 14 35515722 35515722 + 5_prime_UTR_variant 5'UTR SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 9 19 0 ENST00000382406.3:c.-17C>T *6* ENST00000382406 0 +FAM178A UCSF GRCh37 10 102672943 102672943 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 14 29 0 ENST00000238961.4:c.76C>T p.His26Tyr p.H26Y ENST00000238961 NM_018121.3 26 Cat/Tat 0 +FAM179A UCSF GRCh37 2 29274931 29274931 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 46 125 0 ENST00000379558.4:c.3032G>A p.Gly1011Asp p.G1011D ENST00000379558 NM_199280.2 1011 gGc/gAc 0 +FAM196A UCSF GRCh37 10 128973748 128973748 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 54 88 0 ENST00000522781.1:c.912C>T p.Ala304= p.A304= ENST00000522781 NM_001039762.2 304 gcC/gcT 0 +FAM199X UCSF GRCh37 X 103432806 103432806 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 139 114 222 0 ENST00000493442.1:c.815C>T p.Thr272Ile p.T272I ENST00000493442 NM_207318.3 272 aCc/aTc 0 +FAM19A2 UCSF GRCh37 12 62148678 62148678 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0015 P10_Rec Untested WXS Illumina HiSeq 56 40 100 0 ENST00000416284.3:c.234G>A p.Thr78= p.T78= ENST00000416284 NM_178539.4 78 acG/acA 0 +FAM205A UCSF GRCh37 9 34724598 34724598 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 78 181 0 ENST00000378788.3:c.2639C>T p.Pro880Leu p.P880L ENST00000378788 NM_001141917.1 880 cCc/cTc 0 +FAM205A UCSF GRCh37 9 34726559 34726559 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 86 172 0 ENST00000378788.3:c.678G>A p.Glu226= p.E226= ENST00000378788 NM_001141917.1 226 gaG/gaA 0 +FAM208B UCSF GRCh37 10 5772512 5772512 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 143 61 151 0 ENST00000328090.5:c.550C>T p.Leu184Phe p.L184F ENST00000328090 NM_017782.4 184 Ctt/Ttt 0 +FAM208B UCSF GRCh37 10 5804588 5804588 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 170 78 182 0 ENST00000328090.5:c.7268C>T p.Ala2423Val p.A2423V ENST00000328090 NM_017782.4 2423 gCt/gTt 0 +FAM208B UCSF GRCh37 10 5790701 5790701 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 55 129 0 ENST00000328090.5:c.5317G>A p.Ala1773Thr p.A1773T ENST00000328090 NM_017782.4 1773 Gcc/Acc 0 +FAM21A UCSF GRCh37 10 51885899 51885899 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 21 140 0 ENST00000282633.5:c.2771G>A p.Gly924Asp p.G924D ENST00000282633 NM_001005751.1 924 gGt/gAt 0 +FAM22F UCSF GRCh37 9 97081362 97081362 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 71 76 0 ENST00000253262.4:c.1656C>T p.Pro552= p.P552= ENST00000253262 NM_017561.1 552 ccC/ccT 0 +FAM22G UCSF GRCh37 9 99701214 99701214 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 51 140 0 ENST00000372322.3:c.2009G>A p.Gly670Asp p.G670D ENST00000372322 NM_001170741.1 670 gGc/gAc 0 +FAM46A UCSF GRCh37 6 82459934 82459934 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 63 145 0 ENST00000320172.6:c.807G>A p.Gln269= p.Q269= ENST00000320172 NM_017633.2 269 caG/caA 0 +FAM49A UCSF GRCh37 2 16769397 16769397 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 60 127 0 ENST00000381323.3:c.-10G>A p.X4_splice ENST00000381323 NM_030797.3 0 +FAM65B UCSF GRCh37 6 24869322 24869322 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 89 156 0 ENST00000259698.4:c.414G>A p.Lys138= p.K138= ENST00000259698 NM_014722.2 138 aaG/aaA 0 +FAM70A UCSF GRCh37 X 119410813 119410813 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 88 184 0 ENST00000309720.5:c.674C>T p.Ala225Val p.A225V ENST00000309720 NM_017938.3 225 gCc/gTc 0 +FAM75C2 UCSF GRCh37 9 90746733 90746733 + non_coding_transcript_exon_variant RNA SNP C C G NOVEL P10_Rec Untested WXS Illumina HiSeq 131 259 267 1 ENST00000428649.2:n.1248G>C *416* ENST00000428649 0 +FAM84A UCSF GRCh37 2 14774305 14774305 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 24 43 0 ENST00000295092.2:c.202C>T p.Pro68Ser p.P68S ENST00000295092 NM_145175.2 68 Ccc/Tcc 0 +FANCC UCSF GRCh37 9 97869483 97869483 + synonymous_variant Silent SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 59 22 49 0 ENST00000289081.3:c.1398C>T p.Asp466= p.D466= ENST00000289081 NM_000136.2 466 gaC/gaT 0 +FANCG UCSF GRCh37 9 35079448 35079448 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 43 67 0 ENST00000378643.3:c.74G>A p.Arg25Gln p.R25Q ENST00000378643 NM_004629.1 25 cGa/cAa 0 +FANCI UCSF GRCh37 15 89843080 89843080 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 74 156 0 ENST00000310775.7:c.2686G>A p.Gly896Arg p.G896R ENST00000310775 NM_001113378.1 896 Gga/Aga 0 +FASN UCSF GRCh37 17 80045069 80045069 + missense_variant Missense_Mutation SNP G G A snp132_rs4363911 P10_Rec somatic WXS Sanger Illumina HiSeq 16 11 12 0 ENST00000306749.2:c.3284C>T p.Ser1095Phe p.S1095F ENST00000306749 NM_004104.4 1095 tCc/tTc 0 +FBN2 UCSF GRCh37 5 127653923 127653923 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 94 202 0 ENST00000262464.4:c.4635C>T p.Gly1545= p.G1545= ENST00000262464 NM_001999.3 1545 ggC/ggT 0 +FBN3 UCSF GRCh37 19 8150343 8150343 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 7 15 0 ENST00000270509.2:c.6991G>A p.Gly2331Ser p.G2331S ENST00000270509 NM_032447.3 2331 Ggc/Agc 0 +FBN3 UCSF GRCh37 19 8159401 8159401 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 24 49 0 ENST00000270509.2:c.5834G>A p.Cys1945Tyr p.C1945Y ENST00000270509 NM_032447.3 1945 tGc/tAc 0 +FBN3 UCSF GRCh37 19 8160940 8160940 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 45 101 0 ENST00000270509.2:c.5564C>T p.Pro1855Leu p.P1855L ENST00000270509 NM_032447.3 1855 cCt/cTt 0 +FBN3 UCSF GRCh37 19 8130812 8130812 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 29 79 0 ENST00000270509.2:c.8421G>A p.Gln2807= p.Q2807= ENST00000270509 NM_032447.3 2807 caG/caA 0 +FBXL19 UCSF GRCh37 16 30958069 30958069 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 17 39 0 ENST00000380310.2:c.1706G>A p.Gly569Asp p.G569D ENST00000380310 NM_001099784.2 569 gGt/gAt 0 +FBXL22 UCSF GRCh37 15 63889795 63889795 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 39 89 0 ENST00000360587.2:c.204C>T p.Gly68= p.G68= ENST00000360587 NM_203373.2 68 ggC/ggT 0 +FBXL5 UCSF GRCh37 4 15640227 15640227 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 50 128 0 ENST00000341285.3:c.487G>A p.Asp163Asn p.D163N ENST00000341285 NM_001193534.1 163 Gat/Aat 0 +FBXL6 UCSF GRCh37 8 145581850 145581850 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 4 12 0 ENST00000331890.5:c.258G>A p.Arg86= p.R86= ENST00000331890 NM_012162.3 86 agG/agA 0 +FBXO18 UCSF GRCh37 10 5957475 5957475 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 116 48 90 0 ENST00000362091.4:c.1506C>T p.Phe502= p.F502= ENST00000362091 NM_001258453.1 502 ttC/ttT 0 +FBXO24 UCSF GRCh37 7 100193252 100193252 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 70 120 0 ENST00000241071.6:c.1129C>T p.Arg377Ter p.R377* ENST00000241071 NM_033506.2 377 Cga/Tga 0 +FBXO34 UCSF GRCh37 14 55817500 55817500 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 54 143 0 ENST00000313833.4:c.392G>A p.Arg131Lys p.R131K ENST00000313833 NM_017943.3 131 aGg/aAg 0 +FBXO38 UCSF GRCh37 5 147774451 147774451 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 117 84 220 0 ENST00000340253.5:c.112C>T p.Leu38Phe p.L38F ENST00000340253 NM_030793.4 38 Ctt/Ttt 0 +FBXO39 UCSF GRCh37 17 6690267 6690267 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 69 153 0 ENST00000321535.4:c.1192G>A p.Val398Ile p.V398I ENST00000321535 NM_153230.2 398 Gta/Ata 0 +FBXO40 UCSF GRCh37 3 121341947 121341947 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 70 188 0 ENST00000338040.4:c.1671G>A p.Arg557= p.R557= ENST00000338040 NM_016298.3 557 agG/agA 0 +FCGR1A UCSF GRCh37 1 149755806 149755806 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 74 206 0 ENST00000369168.4:c.300C>T p.Ile100= p.I100= ENST00000369168 NM_000566.3 100 atC/atT 0 +FCHSD1 UCSF GRCh37 5 141026182 141026182 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 30 71 0 ENST00000435817.2:c.1032C>T p.Asn344= p.N344= ENST00000435817 NM_033449.2 344 aaC/aaT 0 +FCN1 UCSF GRCh37 9 137809617 137809617 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 43 80 0 ENST00000371806.3:c.101C>T p.Pro34Leu p.P34L ENST00000371806 NM_002003.3 34 cCa/cTa 0 +FDPS UCSF GRCh37 1 155289672 155289672 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 77 139 0 ENST00000356657.6:c.1012G>A p.Val338Ile p.V338I ENST00000356657 NM_001135821.1 338 Gtt/Att 0 +FECH UCSF GRCh37 18 55218022 55218022 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 43 100 0 ENST00000262093.5:c.1194G>A p.Gln398= p.Q398= ENST00000262093 NM_000140.3 398 caG/caA 0 +FER1L5 UCSF GRCh37 2 97370003 97370003 + downstream_gene_variant 3'Flank SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 97 223 0 ENST00000377079 NM_001142292.1 0 +FER1L6 UCSF GRCh37 8 124978277 124978277 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 98 34 84 0 ENST00000399018.1:c.228G>A p.Gly76= p.G76= ENST00000399018 76 ggG/ggA 0 +FERMT1 UCSF GRCh37 20 6060213 6060213 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 53 139 0 ENST00000217289.4:c.1730G>A p.Ser577Asn p.S577N ENST00000217289 NM_017671.4 577 aGc/aAc 0 +FERMT3 UCSF GRCh37 11 63978260 63978260 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 74 100 0 ENST00000279227.5:c.338G>A p.Arg113His p.R113H ENST00000279227 NM_178443.2 113 cGt/cAt 0 +FERMT3 UCSF GRCh37 11 63988578 63988578 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 34 81 0 ENST00000279227.5:c.1648C>T p.Leu550= p.L550= ENST00000279227 NM_178443.2 550 Ctg/Ttg 0 +FFAR3 UCSF GRCh37 19 35849937 35849937 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 216 68 308 0 ENST00000327809.4:c.145G>A p.Ala49Thr p.A49T ENST00000327809 NM_005304.3 49 Gcc/Acc 0 +FGD2 UCSF GRCh37 6 36995292 36995292 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 78 101 0 ENST00000274963.8:c.1693G>A p.Gly565Ser p.G565S ENST00000274963 NM_173558.3 565 Ggc/Agc 0 +FGF12 UCSF GRCh37 3 192125961 192125961 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 24 56 0 ENST00000454309.2:c.52G>A p.Glu18Lys p.E18K ENST00000454309 NM_021032.4 18 Gag/Aag 0 +FGF3 UCSF GRCh37 11 69631120 69631120 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 50 98 0 ENST00000334134.2:c.292G>A p.Ala98Thr p.A98T ENST00000334134 NM_005247.2 98 Gcc/Acc 0 +FGF5 UCSF GRCh37 4 81188231 81188231 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 36 104 0 ENST00000312465.7:c.253G>A p.Gly85Arg p.G85R ENST00000312465 NM_004464.3 85 Ggg/Agg 0 +FGFR1 UCSF GRCh37 8 38271242 38271242 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 14 28 0 ENST00000447712.2:c.2373G>A p.Gly791= p.G791= ENST00000447712 NM_001174063.1 791 ggG/ggA 0 +FGFR3 UCSF GRCh37 4 1807330 1807330 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 44 104 0 ENST00000260795.2:c.1579G>A p.Glu527Lys p.E527K ENST00000260795 527 Gag/Aag 0 +FHL1 UCSF GRCh37 X 135290032 135290032 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 65 130 0 ENST00000345434.3:c.413C>T p.Thr138Ile p.T138I ENST00000345434 138 aCt/aTt 0 +FLG UCSF GRCh37 1 152285468 152285468 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 157 133 267 0 ENST00000368799.1:c.1894G>A p.Glu632Lys p.E632K ENST00000368799 NM_002016.1 632 Gaa/Aaa 0 +FLG UCSF GRCh37 1 152280068 152280068 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 115 214 0 ENST00000368799.1:c.7294G>A p.Gly2432Arg p.G2432R ENST00000368799 NM_002016.1 2432 Ggg/Agg 0 +FLG2 UCSF GRCh37 1 152323669 152323669 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 155 143 235 0 ENST00000388718.5:c.6593G>A p.Gly2198Glu p.G2198E ENST00000388718 NM_001014342.2 2198 gGa/gAa 0 +FLJ43860 UCSF GRCh37 8 142446962 142446962 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 9 19 0 ENST00000606664.1:n.2318C>T *773* ENST00000606664 0 +FLNA UCSF GRCh37 X 153592985 153592985 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 46 84 0 ENST00000369850.3:c.1931C>T p.Ala644Val p.A644V ENST00000369850 NM_001110556.1 644 gCc/gTc 0 +FLNB UCSF GRCh37 3 58149045 58149045 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 5 35 80 0 ENST00000295956.4:c.7186G>A p.Gly2396Arg p.G2396R ENST00000295956 NM_001457.3 2396 Ggg/Agg 0 +FLNC UCSF GRCh37 7 128482991 128482991 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 21 60 0 ENST00000325888.8:c.2533G>A p.Val845Met p.V845M ENST00000325888 NM_001458.4 845 Gtg/Atg 0 +FLRT2 UCSF GRCh37 14 86088382 86088382 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 70 124 0 ENST00000330753.4:c.524C>T p.Pro175Leu p.P175L ENST00000330753 NM_013231.4 175 cCt/cTt 0 +FLT1 UCSF GRCh37 13 28880854 28880854 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 33 93 0 ENST00000282397.4:c.3776C>T p.Thr1259Ile p.T1259I ENST00000282397 NM_002019.4 1259 aCc/aTc 0 +FLT4 UCSF GRCh37 5 180053249 180053249 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 39 90 0 ENST00000261937.6:c.1120G>A p.Ala374Thr p.A374T ENST00000261937 NM_182925.4 374 Gca/Aca 0 +FLVCR1 UCSF GRCh37 1 213061276 213061276 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 41 100 0 ENST00000366971.4:c.1240G>A p.Val414Ile p.V414I ENST00000366971 NM_014053.3 414 Gtt/Att 0 +FLVCR2 UCSF GRCh37 14 76101342 76101342 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 29 80 0 ENST00000238667.4:c.1110G>A p.Arg370= p.R370= ENST00000238667 NM_017791.2 370 agG/agA 0 +FMOD UCSF GRCh37 1 203316597 203316597 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 88 173 0 ENST00000354955.4:c.802C>T p.Pro268Ser p.P268S ENST00000354955 NM_002023.4 268 Ccc/Tcc 0 +FN3K UCSF GRCh37 17 80698656 80698656 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 25 76 0 ENST00000300784.7:c.311G>A p.Gly104Glu p.G104E ENST00000300784 NM_022158.3 104 gGa/gAa 0 +FNDC3B UCSF GRCh37 3 172098803 172098803 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 72 195 0 ENST00000336824.4:c.3223G>A p.Glu1075Lys p.E1075K ENST00000336824 NM_001135095.1 1075 Gag/Aag 0 +FNIP2 UCSF GRCh37 4 159790480 159790480 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 58 89 1 ENST00000264433.6:c.2692G>A p.Gly898Arg p.G898R ENST00000264433 NM_020840.1 898 Gga/Aga 0 +FOXA1 UCSF GRCh37 14 38060636 38060636 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 44 116 0 ENST00000250448.2:c.1353G>A p.Glu451= p.E451= ENST00000250448 NM_004496.3 451 gaG/gaA 0 +FOXD4 UCSF GRCh37 9 116953 116953 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 31 93 0 ENST00000382500.2:c.1167G>A p.Leu389= p.L389= ENST00000382500 NM_207305.4 389 ctG/ctA 0 +FOXM1 UCSF GRCh37 12 2968772 2968772 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 30 76 0 ENST00000359843.3:c.1324G>A p.Glu442Lys p.E442K ENST00000359843 NM_021953.3 442 Gag/Aag 0 +FOXN2 UCSF GRCh37 2 48602534 48602534 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 50 89 0 ENST00000340553.3:c.1248C>T p.Ser416= p.S416= ENST00000340553 NM_002158.3 416 tcC/tcT 0 +FOXO3 UCSF GRCh37 6 108984734 108984734 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 51 97 0 ENST00000343882.6:c.698G>A p.Trp233Ter p.W233* ENST00000343882 NM_201559.2 233 tGg/tAg 0 +FOXRED2 UCSF GRCh37 22 36900392 36900392 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 56 92 0 ENST00000216187.6:c.802G>A p.Asp268Asn p.D268N ENST00000216187 NM_024955.5 268 Gat/Aat 0 +FPGT-TNNI3K UCSF GRCh37 1 74905277 74905277 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 68 142 0 ENST00000326637.3:c.1982G>A p.Gly661Asp p.G661D ENST00000326637 NM_015978.2 661 gGc/gAc 0 +FPGT UCSF GRCh37 1 74667011 74667011 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 39 112 0 ENST00000370891.2:c.260G>A p.Gly87Glu p.G87E ENST00000370891 NM_001112808.2 87 gGa/gAa 0 +FPR2 UCSF GRCh37 19 52272376 52272376 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 94 191 0 ENST00000340023.6:c.465C>T p.Val155= p.V155= ENST00000340023 NM_001005738.1 155 gtC/gtT 0 +FRAS1 UCSF GRCh37 4 79239994 79239994 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 87 162 0 ENST00000264895.6:c.1991G>A p.Gly664Asp p.G664D ENST00000264895 NM_025074.6 664 gGt/gAt 0 +FRAS1 UCSF GRCh37 4 79293994 79293994 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 100 77 186 0 ENST00000264895.6:c.2992G>A p.Asp998Asn p.D998N ENST00000264895 NM_025074.6 998 Gac/Aac 0 +FRMD4A UCSF GRCh37 10 13702466 13702466 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 134 58 107 0 ENST00000357447.2:c.1748C>T p.Pro583Leu p.P583L ENST00000357447 NM_018027.3 583 cCt/cTt 0 +FRMPD2 UCSF GRCh37 10 49395323 49395323 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 22 50 0 ENST00000374201.3:c.2178C>T p.Gly726= p.G726= ENST00000374201 NM_001018071.3 726 ggC/ggT 0 +FRMPD4 UCSF GRCh37 X 12734380 12734380 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 129 102 188 1 ENST00000380682.1:c.1802A>G p.Tyr601Cys p.Y601C ENST00000380682 NM_014728.3 601 tAt/tGt 0 +FRY UCSF GRCh37 13 32735339 32735339 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 72 157 0 ENST00000380250.3:c.1843C>T p.Leu615= p.L615= ENST00000380250 NM_023037.2 615 Ctg/Ttg 0 +FSD2 UCSF GRCh37 15 83437731 83437731 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 71 155 0 ENST00000334574.8:c.1454C>T p.Ala485Val p.A485V ENST00000334574 485 gCt/gTt 0 +FSHR UCSF GRCh37 2 49191001 49191001 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 83 210 0 ENST00000406846.2:c.959C>T p.Ser320Phe p.S320F ENST00000406846 NM_000145.3 320 tCc/tTc 0 +FSTL1 UCSF GRCh37 3 120129807 120129807 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 61 145 0 ENST00000295633.3:c.323C>T p.Ala108Val p.A108V ENST00000295633 NM_007085.4 108 gCc/gTc 0 +FUK UCSF GRCh37 16 70503125 70503125 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 67 121 0 ENST00000288078.6:c.854G>A p.Arg285Lys p.R285K ENST00000288078 NM_145059.2 285 aGg/aAg 0 +FUT4 UCSF GRCh37 11 94278693 94278693 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 40 105 0 ENST00000358752.2:c.1394C>T p.Ala465Val p.A465V ENST00000358752 NM_002033.3 465 gCc/gTc 0 +FZD6 UCSF GRCh37 8 104343670 104343670 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 191 56 120 0 ENST00000358755.4:c.2054C>T p.Ser685Phe p.S685F ENST00000358755 NM_001164616.1 685 tCt/tTt 0 +G6PC3 UCSF GRCh37 17 42153172 42153172 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 83 138 0 ENST00000269097.4:c.802C>T p.Pro268Ser p.P268S ENST00000269097 NM_138387.3 268 Ccc/Tcc 0 +GABPB2 UCSF GRCh37 1 151076124 151076124 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 34 116 0 ENST00000368918.3:c.709C>T p.Pro237Ser p.P237S ENST00000368918 NM_144618.2 237 Ccc/Tcc 0 +GABRA2 UCSF GRCh37 4 46390656 46390656 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 86 209 1 ENST00000356504.1:c.68C>T p.Ala23Val p.A23V ENST00000356504 NM_001114175.1 23 gCc/gTc 0 +GABRE UCSF GRCh37 X 151123325 151123325 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 36 43 57 0 ENST00000370328.3:c.1369T>C p.Phe457Leu p.F457L ENST00000370328 NM_004961.3 457 Ttc/Ctc 0 +GABRR1 UCSF GRCh37 6 89913153 89913153 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 39 138 0 ENST00000454853.2:c.173+1G>A p.X58_splice ENST00000454853 NM_001256704.1 0 +GADD45B UCSF GRCh37 19 2477570 2477570 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 14 31 0 ENST00000215631.4:c.454G>A p.Val152Ile p.V152I ENST00000215631 NM_015675.3 152 Gtc/Atc 0 +GAK UCSF GRCh37 4 860250 860250 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 13 42 0 ENST00000314167.4:c.2945G>A p.Gly982Asp p.G982D ENST00000314167 NM_005255.2 982 gGc/gAc 0 +GAL3ST4 UCSF GRCh37 7 99764134 99764134 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 60 139 0 ENST00000360039.4:c.420C>T p.Asn140= p.N140= ENST00000360039 NM_024637.4 140 aaC/aaT 0 +GALK1 UCSF GRCh37 17 73754159 73754159 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 22 30 0 ENST00000225614.2:c.1157G>A p.Gly386Glu p.G386E ENST00000225614 386 gGa/gAa 0 +GALNT1 UCSF GRCh37 18 33283592 33283592 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 51 149 0 ENST00000269195.5:c.1518G>A p.Trp506Ter p.W506* ENST00000269195 NM_020474.3 506 tgG/tgA 0 +GALNT2 UCSF GRCh37 1 230381809 230381809 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 56 119 0 ENST00000366672.4:c.730G>A p.Asp244Asn p.D244N ENST00000366672 NM_004481.3 244 Gac/Aac 0 +GALNT5 UCSF GRCh37 2 158115100 158115100 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 58 144 0 ENST00000259056.4:c.506C>T p.Pro169Leu p.P169L ENST00000259056 NM_014568.1 169 cCa/cTa 0 +GALNT5 UCSF GRCh37 2 158115564 158115564 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 88 100 165 0 ENST00000259056.4:c.970A>G p.Ile324Val p.I324V ENST00000259056 NM_014568.1 324 Att/Gtt 0 +GALNT6 UCSF GRCh37 12 51752915 51752915 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 137 136 256 0 ENST00000356317.3:c.1368+1G>A p.X456_splice ENST00000356317 NM_007210.3 0 +GALNTL1 UCSF GRCh37 14 69814702 69814702 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 38 113 0 ENST00000337827.4:c.1522C>T p.Pro508Ser p.P508S ENST00000337827 NM_020692.2 508 Cct/Tct 0 +GALR2 UCSF GRCh37 17 74071015 74071015 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 17 20 0 ENST00000329003.3:c.51C>T p.Gly17= p.G17= ENST00000329003 NM_003857.2 17 ggC/ggT 0 +GAPT UCSF GRCh37 5 57790774 57790774 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 66 154 0 ENST00000318469.2:c.411G>A p.Gln137= p.Q137= ENST00000318469 137 caG/caA 0 +GARS UCSF GRCh37 7 30672015 30672015 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 78 189 0 ENST00000389266.3:c.2056C>T p.Leu686= p.L686= ENST00000389266 NM_002047.2 686 Ctg/Ttg 0 +GAS1 UCSF GRCh37 9 89561092 89561092 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 13 31 0 ENST00000298743.7:c.603C>T p.Asp201= p.D201= ENST00000298743 NM_002048.2 201 gaC/gaT 0 +GAS7 UCSF GRCh37 17 9885131 9885131 + synonymous_variant Silent SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 48 50 117 0 ENST00000432992.2:c.375G>A p.Leu125= p.L125= ENST00000432992 NM_201433.1 125 ctG/ctA 0 +GBF1 UCSF GRCh37 10 104128582 104128582 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 64 122 0 ENST00000369983.3:c.2963G>A p.Ser988Asn p.S988N ENST00000369983 NM_004193.2 988 aGc/aAc 0 +GBGT1 UCSF GRCh37 9 136030567 136030567 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 30 89 0 ENST00000372040.3:c.357G>A p.Gly119= p.G119= ENST00000372040 119 ggG/ggA 0 +GCDH UCSF GRCh37 19 13010315 13010315 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 56 35 92 0 ENST00000222214.5:c.1277G>A p.Arg426Lys p.R426K ENST00000222214 NM_000159.3 426 aGa/aAa 0 +GCNT2 UCSF GRCh37 6 10586567 10586567 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 99 192 0 ENST00000379597.3:c.926-35017G>A *309* ENST00000379597 0 +GDF6 UCSF GRCh37 8 97157609 97157609 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 6 30 0 ENST00000287020.5:c.550C>T p.Leu184Phe p.L184F ENST00000287020 NM_001001557.2 184 Ctc/Ttc 0 +GDI2 UCSF GRCh37 10 5815904 5815904 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 137 51 129 0 ENST00000380191.4:c.720G>A p.Arg240= p.R240= ENST00000380191 NM_001494.3 240 agG/agA 0 +GDPD2 UCSF GRCh37 X 69647004 69647004 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 57 119 0 ENST00000374382.3:c.720C>T p.Thr240= p.T240= ENST00000374382 NM_017711.3 240 acC/acT 0 +GDPD3 UCSF GRCh37 16 30123744 30123744 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 49 122 0 ENST00000406256.3:c.366C>T p.Gly122= p.G122= ENST00000406256 NM_024307.2 122 ggC/ggT 0 +GEM UCSF GRCh37 8 95264291 95264291 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 216 62 160 0 ENST00000297596.2:c.569G>A p.Gly190Asp p.G190D ENST00000297596 NM_005261.3 190 gGc/gAc 0 +GEM UCSF GRCh37 8 95262628 95262628 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 209 59 133 0 ENST00000297596.2:c.801G>A p.Arg267= p.R267= ENST00000297596 NM_005261.3 267 agG/agA 0 +GEMIN4 UCSF GRCh37 17 650358 650358 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 105 181 0 ENST00000319004.5:c.925C>T p.Pro309Ser p.P309S ENST00000319004 NM_015721.2 309 Ccc/Tcc 0 +GGCX UCSF GRCh37 2 85785661 85785661 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 78 130 0 ENST00000233838.4:c.441G>A p.Trp147Ter p.W147* ENST00000233838 NM_000821.5 147 tgG/tgA 0 +GGT7 UCSF GRCh37 20 33450626 33450626 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 32 83 0 ENST00000336431.5:c.548G>A p.Gly183Asp p.G183D ENST00000336431 NM_178026.2 183 gGc/gAc 0 +GGT7 UCSF GRCh37 20 33449338 33449338 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 46 127 0 ENST00000336431.5:c.585C>T p.Ile195= p.I195= ENST00000336431 NM_178026.2 195 atC/atT 0 +GIP UCSF GRCh37 17 47039108 47039108 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 16 41 0 ENST00000357424.2:c.331G>A p.Glu111Lys p.E111K ENST00000357424 NM_004123.2 111 Gag/Aag 0 +GJA9 UCSF GRCh37 1 39340782 39340782 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 116 96 171 0 ENST00000357771.3:c.989C>T p.Ser330Phe p.S330F ENST00000357771 NM_030772.4 330 tCt/tTt 0 +GK2 UCSF GRCh37 4 80329033 80329033 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 145 110 223 0 ENST00000358842.3:c.322C>T p.Leu108Phe p.L108F ENST00000358842 NM_033214.2 108 Ctc/Ttc 0 +GLI4 UCSF GRCh37 8 144358409 144358409 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 16 27 0 ENST00000340042.1:c.566G>A p.Gly189Asp p.G189D ENST00000340042 NM_138465.3 189 gGc/gAc 0 +GLIPR1 UCSF GRCh37 12 75892611 75892611 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 101 187 0 ENST00000266659.3:c.654C>T p.Tyr218= p.Y218= ENST00000266659 NM_006851.2 218 taC/taT 0 +GLIS2 UCSF GRCh37 16 4384834 4384834 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 47 84 0 ENST00000262366.3:c.378C>T p.Val126= p.V126= ENST00000262366 126 gtC/gtT 0 +GLIS2 UCSF GRCh37 16 4384886 4384886 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 43 69 0 ENST00000262366.3:c.430C>T p.Leu144= p.L144= ENST00000262366 144 Ctg/Ttg 0 +GLRA4 UCSF GRCh37 X 102968460 102968460 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 53 131 0 ENST00000372617.4:c.1071G>A p.Arg357= p.R357= ENST00000372617 NM_001024452.2 357 agG/agA 0 +GLTPD1 UCSF GRCh37 1 1262672 1262672 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 41 60 0 ENST00000343938.4:c.174C>T p.Val58= p.V58= ENST00000343938 NM_001029885.1 58 gtC/gtT 0 +GLYAT UCSF GRCh37 11 58478192 58478192 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 79 139 0 ENST00000344743.3:c.359C>T p.Ala120Val p.A120V ENST00000344743 NM_201648.2 120 gCc/gTc 0 +GMEB1 UCSF GRCh37 1 29030728 29030728 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 62 192 0 ENST00000294409.2:c.785G>A p.Gly262Glu p.G262E ENST00000294409 NM_006582.3 262 gGa/gAa 0 +GMEB2 UCSF GRCh37 20 62227072 62227072 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 34 70 0 ENST00000266068.1:c.510C>T p.Val170= p.V170= ENST00000266068 170 gtC/gtT 0 +GMIP UCSF GRCh37 19 19747590 19747590 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 49 57 0 ENST00000203556.4:c.1253C>T p.Thr418Ile p.T418I ENST00000203556 NM_016573.2 418 aCt/aTt 0 +GMIP UCSF GRCh37 19 19746530 19746530 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 68 142 0 ENST00000203556.4:c.1328G>A p.Gly443Asp p.G443D ENST00000203556 NM_016573.2 443 gGc/gAc 0 +GMNC UCSF GRCh37 3 190578610 190578610 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 83 196 0 ENST00000442080.1:c.41G>A p.Gly14Glu p.G14E ENST00000442080 NM_001146686.2 14 gGa/gAa 0 +GMNC UCSF GRCh37 3 190573093 190573093 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 68 138 0 ENST00000442080.1:c.996G>A p.Lys332= p.K332= ENST00000442080 NM_001146686.2 332 aaG/aaA 0 +GNE UCSF GRCh37 9 36249212 36249212 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 101 185 0 ENST00000377902.5:c.141C>T p.Gly47= p.G47= ENST00000377902 NM_001190383.1 47 ggC/ggT 0 +GNL1 UCSF GRCh37 6 30520252 30520252 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 61 102 0 ENST00000376621.3:c.1091G>A p.Gly364Asp p.G364D ENST00000376621 NM_005275.3 364 gGc/gAc 0 +GNPTAB UCSF GRCh37 12 102161819 102161819 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 66 158 0 ENST00000299314.7:c.1404C>T p.Cys468= p.C468= ENST00000299314 NM_024312.4 468 tgC/tgT 0 +GOLGA2 UCSF GRCh37 9 131020399 131020399 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 52 87 0 ENST00000421699.2:c.2287G>A p.Val763Met p.V763M ENST00000421699 NM_004486.4 763 Gtg/Atg 0 +GOLGA2 UCSF GRCh37 9 131021652 131021652 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 17 38 0 ENST00000421699.2:c.1810G>A p.Glu604Lys p.E604K ENST00000421699 NM_004486.4 604 Gag/Aag 0 +GOLGA6D UCSF GRCh37 15 75586567 75586567 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P10_Rec Untested WXS Illumina HiSeq 10 0 ENST00000434739.3:c.1924del p.Gln642ArgfsTer15 p.Q642Rfs*15 ENST00000434739 NM_001145224.1 640 gCc/gc 0 +GOLGB1 UCSF GRCh37 3 121416851 121416851 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 105 229 0 ENST00000340645.5:c.2504G>A p.Ser835Asn p.S835N ENST00000340645 NM_001256487.1 835 aGc/aAc 0 +GOLGB1 UCSF GRCh37 3 121421378 121421378 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 95 220 0 ENST00000340645.5:c.1454G>A p.Gly485Glu p.G485E ENST00000340645 NM_001256487.1 485 gGa/gAa 0 +GOLM1 UCSF GRCh37 9 88661417 88661417 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 12 48 0 ENST00000388711.3:c.435G>A p.Gln145= p.Q145= ENST00000388711 NM_177937.2 145 caG/caA 0 +GOLT1A UCSF GRCh37 1 204172028 204172028 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 38 77 0 ENST00000308302.3:c.113G>A p.Gly38Glu p.G38E ENST00000308302 NM_198447.1 38 gGa/gAa 0 +GPAA1 UCSF GRCh37 8 145140933 145140933 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 229 60 95 0 ENST00000355091.4:c.1771G>A p.Glu591Lys p.E591K ENST00000355091 NM_003801.3 591 Gag/Aag 0 +GPATCH2 UCSF GRCh37 1 217793651 217793651 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 88 167 1 ENST00000366935.3:c.247G>A p.Glu83Lys p.E83K ENST00000366935 NM_018040.2 83 Gag/Aag 0 +GPATCH2 UCSF GRCh37 1 217793830 217793830 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 61 170 0 ENST00000366935.3:c.68G>A p.Arg23Lys p.R23K ENST00000366935 NM_018040.2 23 aGa/aAa 0 +GPATCH8 UCSF GRCh37 17 42477705 42477705 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 55 181 0 ENST00000591680.1:c.1740G>A p.Arg580= p.R580= ENST00000591680 NM_001002909.2 580 agG/agA 0 +GPC1 UCSF GRCh37 2 241401769 241401769 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 5 14 0 ENST00000264039.2:c.487C>T p.Leu163= p.L163= ENST00000264039 NM_002081.2 163 Ctg/Ttg 0 +GPC5 UCSF GRCh37 13 92408593 92408593 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 85 193 0 ENST00000377067.3:c.1199G>A p.Gly400Asp p.G400D ENST00000377067 NM_004466.4 400 gGt/gAt 0 +GPCPD1 UCSF GRCh37 20 5550836 5550836 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 50 121 0 ENST00000379019.4:c.1106C>T p.Pro369Leu p.P369L ENST00000379019 NM_019593.3 369 cCc/cTc 0 +GPNMB UCSF GRCh37 7 23300324 23300324 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 94 207 0 ENST00000381990.2:c.950C>T p.Ala317Val p.A317V ENST00000381990 NM_002510.2 317 gCt/gTt 0 +GPR113 UCSF GRCh37 2 26534114 26534114 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 56 76 0 ENST00000311519.1:c.2482G>A p.Gly828Ser p.G828S ENST00000311519 NM_001145168.1 828 Ggc/Agc 0 +GPR113 UCSF GRCh37 2 26533621 26533621 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 39 100 0 ENST00000311519.1:c.2975C>T p.Thr992Ile p.T992I ENST00000311519 NM_001145168.1 992 aCt/aTt 0 +GPR124 UCSF GRCh37 8 37698907 37698907 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 16 25 0 ENST00000412232.2:c.3051C>T p.Val1017= p.V1017= ENST00000412232 NM_032777.9 1017 gtC/gtT 0 +GPR132 UCSF GRCh37 14 105517706 105517706 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 45 110 0 ENST00000329797.3:c.768C>T p.Ala256= p.A256= ENST00000329797 NM_013345.3 256 gcC/gcT 0 +GPR141 UCSF GRCh37 7 37780399 37780399 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 107 171 0 ENST00000334425.1:c.404C>T p.Ala135Val p.A135V ENST00000334425 NM_181791.1 135 gCc/gTc 0 +GPR158 UCSF GRCh37 10 25464933 25464933 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 23 49 0 ENST00000376351.3:c.584C>T p.Thr195Met p.T195M ENST00000376351 NM_020752.2 195 aCg/aTg 0 +GPR161 UCSF GRCh37 1 168066189 168066189 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 51 119 0 ENST00000367835.1:c.656C>T p.Ala219Val p.A219V ENST00000367835 NM_001267610.1 219 gCa/gTa 0 +GPR162 UCSF GRCh37 12 6933578 6933578 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 49 79 0 ENST00000311268.3:c.514G>A p.Val172Ile p.V172I ENST00000311268 NM_019858.1 172 Gtc/Atc 0 +GPR179 UCSF GRCh37 17 36485896 36485896 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 131 88 189 0 ENST00000342292.4:c.3556G>A p.Gly1186Ser p.G1186S ENST00000342292 NM_001004334.2 1186 Ggt/Agt 0 +GPR182 UCSF GRCh37 12 57390041 57390041 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 84 173 0 ENST00000300098.1:c.1048G>A p.Ala350Thr p.A350T ENST00000300098 NM_007264.3 350 Gcc/Acc 0 +GPR25 UCSF GRCh37 1 200842190 200842190 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 7 11 0 ENST00000304244.2:c.25C>T p.Pro9Ser p.P9S ENST00000304244 NM_005298.3 9 Ccc/Tcc 0 +GPR26 UCSF GRCh37 10 125447457 125447457 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 49 105 0 ENST00000284674.1:c.795C>T p.Leu265= p.L265= ENST00000284674 NM_153442.3 265 ctC/ctT 0 +GPR44 UCSF GRCh37 11 60620894 60620894 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 14 22 0 ENST00000332539.4:c.302C>T p.Thr101Ile p.T101I ENST00000332539 NM_004778.2 101 aCc/aTc 0 +GPR98 UCSF GRCh37 5 90087119 90087119 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 71 181 0 ENST00000405460.2:c.14473G>A p.Asp4825Asn p.D4825N ENST00000405460 NM_032119.3 4825 Gat/Aat 0 +GPR98 UCSF GRCh37 5 89941817 89941817 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 65 157 0 ENST00000405460.2:c.2931C>T p.Ile977= p.I977= ENST00000405460 NM_032119.3 977 atC/atT 0 +GPRC5D UCSF GRCh37 12 13102939 13102939 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 100 79 177 0 ENST00000228887.1:c.380C>T p.Thr127Met p.T127M ENST00000228887 NM_018654.1 127 aCg/aTg 0 +GPRC5D UCSF GRCh37 12 13103201 13103201 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 65 151 0 ENST00000228887.1:c.118C>T p.Leu40= p.L40= ENST00000228887 NM_018654.1 40 Cta/Tta 0 +GPRIN2 UCSF GRCh37 10 47000217 47000217 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.067,1000g2011may_all_0.1080,snp132_rs72780221 P10_Rec Untested WXS Illumina HiSeq 31 7 21 0 ENST00000374314.4:c.1337G>A p.Arg446His p.R446H ENST00000374314 446 cGc/cAc 0 +GPS1 UCSF GRCh37 17 80013898 80013898 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 28 39 0 ENST00000306823.6:c.868G>A p.Ala290Thr p.A290T ENST00000306823 290 Gcc/Acc 0 +GPSM3 UCSF GRCh37 6 32159599 32159599 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 35 65 0 ENST00000375040.3:c.232G>A p.Glu78Lys p.E78K ENST00000375040 NM_001276501.1 78 Gag/Aag 0 +GPSM3 UCSF GRCh37 6 32159654 32159654 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 18 54 0 ENST00000375040.3:c.177C>T p.Ser59= p.S59= ENST00000375040 NM_001276501.1 59 tcC/tcT 0 +GPT UCSF GRCh37 8 145731405 145731405 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 20 57 0 ENST00000394955.2:c.847G>A p.Gly283Ser p.G283S ENST00000394955 NM_005309.2 283 Ggt/Agt 0 +GPX3 UCSF GRCh37 5 150406564 150406564 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 60 121 0 ENST00000388825.4:c.345C>T p.Ile115= p.I115= ENST00000388825 NM_002084.3 115 atC/atT 0 +GRAMD1B UCSF GRCh37 11 123489414 123489414 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 47 133 0 ENST00000529750.1:c.1915G>A p.Val639Ile p.V639I ENST00000529750 NM_020716.1 639 Gtc/Atc 0 +GREB1 UCSF GRCh37 2 11756768 11756768 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 122 112 206 0 ENST00000234142.5:c.3334G>A p.Glu1112Lys p.E1112K ENST00000234142 1112 Gag/Aag 0 +GREB1L UCSF GRCh37 18 18981246 18981246 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 68 152 0 ENST00000424526.1:c.668C>T p.Ser223Phe p.S223F ENST00000424526 NM_001142966.1 223 tCc/tTc 0 +GREB1L UCSF GRCh37 18 19079801 19079801 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 54 91 0 ENST00000424526.1:c.3503G>A p.Gly1168Glu p.G1168E ENST00000424526 NM_001142966.1 1168 gGg/gAg 0 +GREB1L UCSF GRCh37 18 19019504 19019504 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 72 155 0 ENST00000424526.1:c.855C>T p.Ser285= p.S285= ENST00000424526 NM_001142966.1 285 agC/agT 0 +GRIA2 UCSF GRCh37 4 158262441 158262441 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 71 180 0 ENST00000264426.9:c.1870G>A p.Gly624Ser p.G624S ENST00000264426 NM_001083619.1 624 Ggt/Agt 0 +GRID2 UCSF GRCh37 4 94693496 94693496 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 69 162 0 ENST00000282020.4:c.2871G>A p.Val957= p.V957= ENST00000282020 NM_001510.2 957 gtG/gtA 0 +GRIK2 UCSF GRCh37 6 102124666 102124666 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 44 124 0 ENST00000421544.1:c.710G>A p.Gly237Asp p.G237D ENST00000421544 NM_021956.4 237 gGc/gAc 0 +GRIK3 UCSF GRCh37 1 37271904 37271904 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 30 56 0 ENST00000373091.3:c.2115G>A p.Glu705= p.E705= ENST00000373091 NM_000831.3 705 gaG/gaA 0 +GRIN2B UCSF GRCh37 12 13716834 13716834 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 46 69 0 ENST00000609686.1:c.3338C>T p.Pro1113Leu p.P1113L ENST00000609686 NM_000834.3 1113 cCg/cTg 0 +GRIN2B UCSF GRCh37 12 14018739 14018739 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 110 221 0 ENST00000609686.1:c.404C>T p.Ala135Val p.A135V ENST00000609686 NM_000834.3 135 gCa/gTa 0 +GRIN2D UCSF GRCh37 19 48908291 48908291 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 32 40 0 ENST00000263269.3:c.766G>A p.Val256Met p.V256M ENST00000263269 NM_000836.2 256 Gtg/Atg 0 +GRIN3B UCSF GRCh37 19 1005335 1005335 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 54 100 0 ENST00000234389.3:c.1835C>T p.Thr612Ile p.T612I ENST00000234389 NM_138690.1 612 aCc/aTc 0 +GRINA UCSF GRCh37 8 145066899 145066899 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 161 27 60 0 ENST00000313269.5:c.1006C>T p.Gln336Ter p.Q336* ENST00000313269 NM_000837.1 336 Cag/Tag 0 +GRK5 UCSF GRCh37 10 121207635 121207635 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 57 102 0 ENST00000392870.2:c.1267C>T p.Leu423= p.L423= ENST00000392870 NM_005308.2 423 Ctg/Ttg 0 +GRM3 UCSF GRCh37 7 86394480 86394480 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 101 223 0 ENST00000361669.2:c.19C>T p.Leu7= p.L7= ENST00000361669 NM_000840.2 7 Ctg/Ttg 0 +GRM4 UCSF GRCh37 6 34008508 34008508 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 48 81 0 ENST00000538487.2:c.1186C>T p.Gln396Ter p.Q396* ENST00000538487 NM_000841.2 396 Cag/Tag 0 +GRWD1 UCSF GRCh37 19 48950053 48950053 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 36 78 0 ENST00000253237.5:c.421C>T p.Leu141= p.L141= ENST00000253237 NM_031485.3 141 Ctg/Ttg 0 +GRXCR1 UCSF GRCh37 4 42964927 42964927 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 143 109 220 0 ENST00000399770.2:c.403G>A p.Glu135Lys p.E135K ENST00000399770 NM_001080476.2 135 Gaa/Aaa 0 +GSTCD UCSF GRCh37 4 106766655 106766655 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 57 147 0 ENST00000360505.5:c.1823G>A p.Gly608Glu p.G608E ENST00000360505 NM_001031720.3 608 gGa/gAa 0 +GSTM4 UCSF GRCh37 1 110200394 110200394 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 79 176 0 ENST00000369836.4:c.260G>A p.Cys87Tyr p.C87Y ENST00000369836 NM_000850.4 87 tGt/tAt 0 +GSTO1 UCSF GRCh37 10 106019413 106019413 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 65 145 0 ENST00000369713.5:c.223C>T p.Leu75= p.L75= ENST00000369713 NM_004832.2 75 Ctg/Ttg 0 +GSTT2 UCSF GRCh37 22 24323227 24323227 + splice_donor_variant Splice_Site SNP G G A 1000g2010nov_all_0.153,1000g2011may_all_0.2294,snp132_rs5996646 P10_Rec Untested WXS Illumina HiSeq 62 48 77 0 ENST00000215780.5:c.200+1G>A p.X67_splice ENST00000215780 NM_000854.3 0 +GTDC1 UCSF GRCh37 2 144709586 144709586 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 77 171 0 ENST00000344850.4:c.1256G>A p.Cys419Tyr p.C419Y ENST00000344850 419 tGc/tAc 0 +GTF3C5 UCSF GRCh37 9 135931419 135931419 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 24 68 0 ENST00000372097.5:c.1188G>A p.Arg396= p.R396= ENST00000372097 NM_012087.3 396 cgG/cgA 0 +GTPBP1 UCSF GRCh37 22 39123237 39123237 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 5 84 150 1 ENST00000216044.5:c.1421G>A p.Arg474Gln p.R474Q ENST00000216044 NM_004286.4 474 cGg/cAg 0 +GTPBP4 UCSF GRCh37 10 1046647 1046647 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 48 103 0 ENST00000360803.4:c.685C>T p.Pro229Ser p.P229S ENST00000360803 NM_012341.2 229 Cct/Tct 0 +GUK1 UCSF GRCh37 1 228336552 228336552 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 8 21 0 ENST00000312726.4:c.*154G>A *52* ENST00000312726 NM_000858.5 0 +GZMA UCSF GRCh37 5 54404211 54404211 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 50 147 0 ENST00000274306.6:c.616G>A p.Asp206Asn p.D206N ENST00000274306 NM_006144.3 206 Gac/Aac 0 +HADHB UCSF GRCh37 2 26508395 26508395 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 39 116 0 ENST00000317799.5:c.1345G>A p.Gly449Arg p.G449R ENST00000317799 NM_000183.2 449 Gga/Aga 0 +HAO1 UCSF GRCh37 20 7864306 7864306 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 45 133 0 ENST00000378789.3:c.1047C>T p.Cys349= p.C349= ENST00000378789 NM_017545.2 349 tgC/tgT 0 +HARS2 UCSF GRCh37 5 140076985 140076985 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 53 105 0 ENST00000230771.3:c.1191G>A p.Arg397= p.R397= ENST00000230771 NM_012208.3 397 agG/agA 0 +HAUS5 UCSF GRCh37 19 36104642 36104642 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 35 86 0 ENST00000203166.5:c.109G>A p.Gly37Ser p.G37S ENST00000203166 NM_015302.1 37 Ggc/Agc 0 +HBEGF UCSF GRCh37 5 139722342 139722342 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 121 124 238 0 ENST00000230990.6:c.276G>A p.Gly92= p.G92= ENST00000230990 NM_001945.2 92 ggG/ggA 0 +HCFC1 UCSF GRCh37 X 153215898 153215898 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 55 78 0 ENST00000310441.7:c.5800G>A p.Ala1934Thr p.A1934T ENST00000310441 NM_005334.2 1934 Gct/Act 0 +HCFC1 UCSF GRCh37 X 153228826 153228826 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 63 112 0 ENST00000310441.7:c.562G>A p.Asp188Asn p.D188N ENST00000310441 NM_005334.2 188 Gac/Aac 0 +HCFC1 UCSF GRCh37 X 153217516 153217516 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 10 18 0 ENST00000310441.7:c.5036C>T p.Ala1679Val p.A1679V ENST00000310441 NM_005334.2 1679 gCc/gTc 0 +HCRTR2 UCSF GRCh37 6 55142286 55142286 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 55 129 0 ENST00000370862.3:c.871G>A p.Ala291Thr p.A291T ENST00000370862 NM_001526.3 291 Gct/Act 0 +HDAC1 UCSF GRCh37 1 32793232 32793232 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 52 127 0 ENST00000373548.3:c.590C>T p.Ser197Phe p.S197F ENST00000373548 NM_004964.2 197 tCc/tTc 0 +HDAC2 UCSF GRCh37 6 114274491 114274491 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 108 186 0 ENST00000519065.1:c.589G>A p.Val197Ile p.V197I ENST00000519065 197 Gta/Ata 0 +HDAC4 UCSF GRCh37 2 240024572 240024572 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 33 65 0 ENST00000345617.3:c.2118C>T p.Ala706= p.A706= ENST00000345617 NM_006037.3 706 gcC/gcT 0 +HDAC7 UCSF GRCh37 12 48189160 48189160 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 15 28 0 ENST00000427332.2:c.974C>T p.Pro325Leu p.P325L ENST00000427332 325 cCc/cTc 0 +HDLBP UCSF GRCh37 2 242179450 242179450 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 87 171 0 ENST00000391975.1:c.2257G>A p.Val753Met p.V753M ENST00000391975 NM_203346.3 753 Gtg/Atg 0 +HDX UCSF GRCh37 X 83599315 83599315 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 61 182 0 ENST00000297977.5:c.1603G>A p.Glu535Lys p.E535K ENST00000297977 NM_001177479.1 535 Gag/Aag 0 +HEATR8 UCSF GRCh37 1 55166075 55166075 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 33 52 0 ENST00000421030.2:c.3046C>T p.Pro1016Ser p.P1016S ENST00000421030 NM_001039464.2 1016 Ccc/Tcc 0 +HECA UCSF GRCh37 6 139488196 139488196 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 45 95 1 ENST00000367658.2:c.1047C>T p.Leu349= p.L349= ENST00000367658 NM_016217.2 349 ctC/ctT 0 +HECTD1 UCSF GRCh37 14 31578805 31578805 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 31 72 0 ENST00000399332.1:c.6279-1G>A p.X2093_splice ENST00000399332 NM_015382.2 0 +HECTD1 UCSF GRCh37 14 31617926 31617926 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 46 100 0 ENST00000399332.1:c.2496+1G>A p.X832_splice ENST00000399332 NM_015382.2 0 +HECTD1 UCSF GRCh37 14 31638597 31638597 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 83 208 0 ENST00000399332.1:c.1410G>A p.Arg470= p.R470= ENST00000399332 NM_015382.2 470 agG/agA 0 +HELQ UCSF GRCh37 4 84328662 84328662 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 39 90 0 ENST00000295488.3:c.3250C>T p.Leu1084= p.L1084= ENST00000295488 NM_133636.2 1084 Cta/Tta 0 +HEMGN UCSF GRCh37 9 100689682 100689682 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 143 69 156 0 ENST00000259456.3:c.1439G>A p.Ser480Asn p.S480N ENST00000259456 NM_018437.4 480 aGt/aAt 0 +HEPHL1 UCSF GRCh37 11 93845043 93845043 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 123 204 1 ENST00000315765.9:c.3463C>T p.Pro1155Ser p.P1155S ENST00000315765 NM_001098672.1 1155 Ccc/Tcc 0 +HEPN1 UCSF GRCh37 11 124789666 124789666 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 47 86 0 ENST00000408930.5:c.20G>A p.Gly7Glu p.G7E ENST00000408930 NM_001037558.2 7 gGa/gAa 0 +HERC1 UCSF GRCh37 15 64041674 64041674 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 68 162 0 ENST00000443617.2:c.2111G>A p.Gly704Asp p.G704D ENST00000443617 NM_003922.3 704 gGt/gAt 0 +HERC1 UCSF GRCh37 15 63948464 63948464 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 85 136 0 ENST00000443617.2:c.9693G>A p.Gly3231= p.G3231= ENST00000443617 NM_003922.3 3231 ggG/ggA 0 +HERC1 UCSF GRCh37 15 63915067 63915067 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 21 89 0 ENST00000443617.2:c.13635C>T p.Asp4545= p.D4545= ENST00000443617 NM_003922.3 4545 gaC/gaT 0 +HERC2 UCSF GRCh37 15 28467217 28467217 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 78 228 0 ENST00000261609.7:c.5609G>A p.Gly1870Glu p.G1870E ENST00000261609 NM_004667.5 1870 gGa/gAa 0 +HERC2 UCSF GRCh37 15 28389922 28389922 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 49 89 0 ENST00000261609.7:c.11037G>A p.Glu3679= p.E3679= ENST00000261609 NM_004667.5 3679 gaG/gaA 0 +HEXDC UCSF GRCh37 17 80393661 80393661 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 50 78 0 ENST00000327949.9:c.544G>A p.Ala182Thr p.A182T ENST00000327949 182 Gcc/Acc 0 +HEXDC UCSF GRCh37 17 80400336 80400336 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 41 81 0 ENST00000327949.9:c.*76G>A *26* ENST00000327949 0 +HHAT UCSF GRCh37 1 210591662 210591662 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 54 137 0 ENST00000261458.3:c.849G>A p.Trp283Ter p.W283* ENST00000261458 NM_018194.4 283 tgG/tgA 0 +HHIPL2 UCSF GRCh37 1 222717259 222717259 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 96 0 ENST00000343410.6:c.594C>T p.Ala198= p.A198= ENST00000343410 NM_024746.3 198 gcC/gcT 0 +HHLA1 UCSF GRCh37 8 133088376 133088376 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 23 38 0 ENST00000434736.2:c.1349G>A p.Gly450Asp p.G450D ENST00000434736 450 gGt/gAt 0 +HIBCH UCSF GRCh37 2 191125913 191125913 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 56 159 0 ENST00000359678.5:c.486G>A p.Lys162= p.K162= ENST00000359678 NM_198047.2 162 aaG/aaA 0 +HIF1A UCSF GRCh37 14 62194253 62194253 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 68 178 0 ENST00000337138.4:c.653C>T p.Thr218Ile p.T218I ENST00000337138 NM_001530.3 218 aCc/aTc 0 +HIF3A UCSF GRCh37 19 46811518 46811518 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 40 136 0 ENST00000377670.4:c.404C>T p.Pro135Leu p.P135L ENST00000377670 NM_152795.3 135 cCc/cTc 0 +HIP1 UCSF GRCh37 7 75221383 75221383 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 79 151 0 ENST00000336926.6:c.375C>T p.Ser125= p.S125= ENST00000336926 NM_005338.6 125 agC/agT 0 +HIPK1 UCSF GRCh37 1 114499778 114499778 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 65 160 0 ENST00000369558.1:c.1625G>A p.Cys542Tyr p.C542Y ENST00000369558 542 tGc/tAc 0 +HIPK1 UCSF GRCh37 1 114499776 114499776 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 67 161 0 ENST00000369558.1:c.1623C>T p.Ile541= p.I541= ENST00000369558 541 atC/atT 0 +HIST1H2BC UCSF GRCh37 6 26123872 26123872 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 84 177 0 ENST00000314332.5:c.261C>T p.Arg87= p.R87= ENST00000314332 87 cgC/cgT 0 +HIVEP3 UCSF GRCh37 1 42047716 42047716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 74 141 0 ENST00000247584.5:c.2753G>A p.Gly918Glu p.G918E ENST00000247584 918 gGg/gAg 0 +HJURP UCSF GRCh37 2 234750489 234750489 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 71 128 0 ENST00000411486.2:c.937G>A p.Ala313Thr p.A313T ENST00000411486 NM_018410.3 313 Gcc/Acc 0 +HJURP UCSF GRCh37 2 234754383 234754383 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 54 128 0 ENST00000411486.2:c.486G>A p.Glu162= p.E162= ENST00000411486 NM_018410.3 162 gaG/gaA 0 +HLA-G UCSF GRCh37 6 29795629 29795629 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 43 20 83 0 ENST00000360323.6:c.8T>C p.Val3Ala p.V3A ENST00000360323 3 gTc/gCc 0 +HMBS UCSF GRCh37 11 118963857 118963857 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 62 126 0 ENST00000278715.3:c.950G>A p.Gly317Asp p.G317D ENST00000278715 NM_000190.3 317 gGc/gAc 0 +HMCN1 UCSF GRCh37 1 186134277 186134277 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 52 118 0 ENST00000271588.4:c.15291C>T p.Thr5097= p.T5097= ENST00000271588 NM_031935.2 5097 acC/acT 0 +HMGCLL1 UCSF GRCh37 6 55360216 55360216 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 35 149 0 ENST00000398661.2:c.885+1G>A p.X295_splice ENST00000398661 NM_019036.2 0 +HMHA1 UCSF GRCh37 19 1083224 1083224 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 12 0 ENST00000313093.2:c.2827C>T p.Pro943Ser p.P943S ENST00000313093 NM_012292.3 943 Ccc/Tcc 0 +HMX3 UCSF GRCh37 10 124896686 124896686 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 11 31 0 ENST00000357878.5:c.513C>T p.Ser171= p.S171= ENST00000357878 NM_001105574.1 171 agC/agT 0 +HNF4G UCSF GRCh37 8 76463725 76463725 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 45 101 0 ENST00000354370.1:c.344G>A p.Arg115His p.R115H ENST00000354370 115 cGc/cAc 0 +HNRNPA1 UCSF GRCh37 12 54678084 54678084 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 62 164 0 ENST00000340913.6:c.1106G>A p.Gly369Asp p.G369D ENST00000340913 NM_002136.2 369 gGc/gAc 0 +HNRNPU UCSF GRCh37 1 245026995 245026995 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 10 12 0 ENST00000283179.9:c.615G>A p.Gln205= p.Q205= ENST00000283179 205 caG/caA 0 +HNRNPUL2 UCSF GRCh37 11 62483026 62483026 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 64 137 0 ENST00000301785.5:c.2109G>A p.Gly703= p.G703= ENST00000301785 NM_001079559.2 703 ggG/ggA 0 +HNRNPUL2 UCSF GRCh37 11 62487502 62487502 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 84 144 0 ENST00000301785.5:c.1773G>A p.Glu591= p.E591= ENST00000301785 NM_001079559.2 591 gaG/gaA 0 +HOMEZ UCSF GRCh37 14 23745503 23745503 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 95 196 0 ENST00000357460.5:c.934G>A p.Val312Ile p.V312I ENST00000357460 NM_020834.2 312 Gtc/Atc 0 +HOMEZ UCSF GRCh37 14 23745147 23745147 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 116 105 176 0 ENST00000357460.5:c.1290C>T p.Phe430= p.F430= ENST00000357460 NM_020834.2 430 ttC/ttT 0 +HOXA5 UCSF GRCh37 7 27182773 27182773 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 29 63 0 ENST00000222726.3:c.454G>A p.Asp152Asn p.D152N ENST00000222726 NM_019102.3 152 Gac/Aac 0 +HOXB3 UCSF GRCh37 17 46627775 46627775 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 19 52 0 ENST00000311626.4:c.1217C>T p.Thr406Ile p.T406I ENST00000311626 NM_002146.4 406 aCc/aTc 0 +HOXC9 UCSF GRCh37 12 54396377 54396377 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 70 177 0 ENST00000303450.4:c.702G>A p.Arg234= p.R234= ENST00000303450 NM_006897.1 234 cgG/cgA 0 +HOXD12 UCSF GRCh37 2 176964675 176964675 + missense_variant Missense_Mutation SNP T T G NOVEL P10_Rec Untested WXS Illumina HiSeq 39 32 57 1 ENST00000406506.2:c.146T>G p.Leu49Arg p.L49R ENST00000406506 49 cTg/cGg 0 +HPCAL4 UCSF GRCh37 1 40149716 40149716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 16 51 0 ENST00000372844.3:c.271G>A p.Val91Ile p.V91I ENST00000372844 NM_016257.2 91 Gtc/Atc 0 +HR UCSF GRCh37 8 21977951 21977951 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 48 78 0 ENST00000381418.4:c.2680C>T p.Leu894Phe p.L894F ENST00000381418 NM_005144.4 894 Ctt/Ttt 0 +HRC UCSF GRCh37 19 49656719 49656719 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 23 42 0 ENST00000252825.4:c.1776C>T p.Asp592= p.D592= ENST00000252825 NM_002152.2 592 gaC/gaT 0 +HRNR UCSF GRCh37 1 152185889 152185889 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 8 25 0 ENST00000368801.2:c.8216G>A p.Ser2739Asn p.S2739N ENST00000368801 NM_001009931.2 2739 aGc/aAc 0 +HRNR UCSF GRCh37 1 152191061 152191061 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 98 263 0 ENST00000368801.2:c.3044G>A p.Gly1015Glu p.G1015E ENST00000368801 NM_001009931.2 1015 gGg/gAg 0 +HRNR UCSF GRCh37 1 152188064 152188064 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 488 73 912 0 ENST00000368801.2:c.6041C>T p.Ser2014Phe p.S2014F ENST00000368801 NM_001009931.2 2014 tCt/tTt 0 +HRNR UCSF GRCh37 1 152193068 152193068 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 111 207 0 ENST00000368801.2:c.1037C>T p.Ser346Phe p.S346F ENST00000368801 NM_001009931.2 346 tCt/tTt 0 +HS3ST3A1 UCSF GRCh37 17 13400067 13400067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 42 124 0 ENST00000284110.1:c.668G>A p.Arg223Gln p.R223Q ENST00000284110 NM_006042.1 223 cGg/cAg 0 +HS3ST3B1 UCSF GRCh37 17 14248413 14248413 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 1 38 46 0 ENST00000360954.2:c.623G>A p.Arg208Gln p.R208Q ENST00000360954 NM_006041.1 208 cGg/cAg 0 +HS3ST4 UCSF GRCh37 16 25704412 25704412 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 19 42 0 ENST00000331351.5:c.674C>T p.Ala225Val p.A225V ENST00000331351 NM_006040.2 225 gCg/gTg 0 +HSD11B2 UCSF GRCh37 16 67470844 67470844 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 26 72 0 ENST00000326152.5:c.1156C>T p.Pro386Ser p.P386S ENST00000326152 NM_000196.3 386 Cca/Tca 0 +HSDL1 UCSF GRCh37 16 84158330 84158330 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 41 84 0 ENST00000219439.4:c.898C>T p.Leu300Phe p.L300F ENST00000219439 NM_001146051.1 300 Ctt/Ttt 0 +HSF1 UCSF GRCh37 8 145533197 145533197 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 185 43 102 0 ENST00000528838.1:c.283G>A p.Asp95Asn p.D95N ENST00000528838 NM_005526.2 95 Gac/Aac 0 +HSPA14 UCSF GRCh37 10 14890607 14890607 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 37 108 0 ENST00000378372.3:c.222-1G>A p.X74_splice ENST00000378372 NM_016299.3 0 +HSPA1A UCSF GRCh37 6 31783580 31783580 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 34 87 0 ENST00000375651.5:c.47C>T p.Ser16Phe p.S16F ENST00000375651 NM_005345.5 16 tCc/tTc 0 +HSPA5 UCSF GRCh37 9 128001393 128001393 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 168 72 146 0 ENST00000324460.6:c.823G>A p.Gly275Ser p.G275S ENST00000324460 NM_005347.4 275 Ggc/Agc 0 +HSPA5 UCSF GRCh37 9 128001379 128001379 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 156 77 144 0 ENST00000324460.6:c.837G>A p.Arg279= p.R279= ENST00000324460 NM_005347.4 279 agG/agA 0 +HSPG2 UCSF GRCh37 1 22206914 22206914 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 32 54 0 ENST00000374695.3:c.2137G>A p.Asp713Asn p.D713N ENST00000374695 NM_005529.5 713 Gat/Aat 0 +HSPG2 UCSF GRCh37 1 22202774 22202774 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 20 9 23 0 ENST00000374695.3:c.2951T>C p.Leu984Pro p.L984P ENST00000374695 NM_005529.5 984 cTc/cCc 0 +HTATSF1 UCSF GRCh37 X 135592333 135592333 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 117 243 0 ENST00000218364.4:c.1017C>T p.Gly339= p.G339= ENST00000218364 NM_014500.4 339 ggC/ggT 0 +HTR3A UCSF GRCh37 11 113853846 113853846 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 62 152 0 ENST00000504030.2:c.379G>A p.Asp127Asn p.D127N ENST00000504030 127 Gat/Aat 0 +HTRA1 UCSF GRCh37 10 124248504 124248504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 54 132 0 ENST00000368984.3:c.559G>A p.Glu187Lys p.E187K ENST00000368984 NM_002775.4 187 Gaa/Aaa 0 +HTT UCSF GRCh37 4 3144503 3144503 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 84 141 0 ENST00000355072.5:c.2956G>A p.Gly986Ser p.G986S ENST00000355072 NM_002111.6 986 Ggc/Agc 0 +HUWE1 UCSF GRCh37 X 53591615 53591615 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 59 133 0 ENST00000262854.6:c.6949G>A p.Asp2317Asn p.D2317N ENST00000262854 NM_031407.5 2317 Gat/Aat 0 +HUWE1 UCSF GRCh37 X 53563380 53563380 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 66 231 0 ENST00000262854.6:c.12386C>T p.Thr4129Ile p.T4129I ENST00000262854 NM_031407.5 4129 aCt/aTt 0 +HUWE1 UCSF GRCh37 X 53566032 53566032 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 18 52 0 ENST00000262854.6:c.11642C>T p.Pro3881Leu p.P3881L ENST00000262854 NM_031407.5 3881 cCt/cTt 0 +HYAL2 UCSF GRCh37 3 50357097 50357097 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 34 53 0 ENST00000357750.4:c.824C>T p.Ala275Val p.A275V ENST00000357750 NM_003773.4 275 gCc/gTc 0 +HYDIN UCSF GRCh37 16 70989284 70989284 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 211 69 265 0 ENST00000393567.2:c.6310G>A p.Glu2104Lys p.E2104K ENST00000393567 NM_001270974.1 2104 Gag/Aag 0 +HYDIN UCSF GRCh37 16 71061635 71061635 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 196 56 254 0 ENST00000393567.2:c.2912C>T p.Pro971Leu p.P971L ENST00000393567 NM_001270974.1 971 cCc/cTc 0 +HYOU1 UCSF GRCh37 11 118924874 118924874 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 70 143 0 ENST00000404233.3:c.753G>A p.Lys251= p.K251= ENST00000404233 NM_001130991.1 251 aaG/aaA 0 +IARS2 UCSF GRCh37 1 220300096 220300096 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 67 146 0 ENST00000366922.1:c.1532G>A p.Gly511Asp p.G511D ENST00000366922 511 gGt/gAt 0 +IBA57 UCSF GRCh37 1 228363087 228363087 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 59 130 0 ENST00000366711.3:c.944G>A p.Gly315Asp p.G315D ENST00000366711 NM_001010867.2 315 gGc/gAc 0 +IBTK UCSF GRCh37 6 82935319 82935319 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 62 143 2 ENST00000306270.7:c.700G>A p.Val234Met p.V234M ENST00000306270 NM_015525.2 234 Gtg/Atg 0 +ICAM1 UCSF GRCh37 19 10395520 10395520 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 39 81 0 ENST00000264832.3:c.1242G>A p.Gln414= p.Q414= ENST00000264832 NM_000201.2 414 caG/caA 0 +ICAM2 UCSF GRCh37 17 62082531 62082531 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 50 100 0 ENST00000412356.1:c.264C>T p.Val88= p.V88= ENST00000412356 NM_001099786.1 88 gtC/gtT 0 +ICAM3 UCSF GRCh37 19 10445447 10445447 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 32 84 0 ENST00000160262.5:c.949C>T p.Pro317Ser p.P317S ENST00000160262 NM_002162.3 317 Ccc/Tcc 0 +ICMT UCSF GRCh37 1 6292032 6292032 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 64 154 0 ENST00000343813.5:c.602C>T p.Thr201Ile p.T201I ENST00000343813 NM_012405.3 201 aCc/aTc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 79 72 125 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IDO1 UCSF GRCh37 8 39775667 39775667 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 112 192 0 ENST00000518237.1:c.244G>A p.Val82Ile p.V82I ENST00000518237 NM_002164.5 82 Gtt/Att 0 +IFFO2 UCSF GRCh37 1 19235148 19235148 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 31 85 0 ENST00000455833.2:c.1461C>T p.Ser487= p.S487= ENST00000455833 NM_001136265.1 487 tcC/tcT 0 +IFI27L1 UCSF GRCh37 14 94568225 94568225 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 35 68 0 ENST00000393115.3:c.127G>A p.Ala43Thr p.A43T ENST00000393115 NM_145249.2 43 Gca/Aca 0 +IFIH1 UCSF GRCh37 2 163144827 163144827 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 56 119 0 ENST00000263642.2:c.913G>A p.Glu305Lys p.E305K ENST00000263642 NM_022168.3 305 Gaa/Aaa 0 +IFIT3 UCSF GRCh37 10 91098440 91098440 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 47 131 1 ENST00000371811.4:c.28G>A p.Glu10Lys p.E10K ENST00000371811 NM_001031683.2 10 Gag/Aag 0 +IFITM1 UCSF GRCh37 11 314971 314971 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 44 132 0 ENST00000328221.5:c.236C>T p.Ala79Val p.A79V ENST00000328221 79 gCc/gTc 0 +IFNAR2 UCSF GRCh37 21 34635734 34635734 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 96 166 0 ENST00000342136.4:c.1477G>A p.Asp493Asn p.D493N ENST00000342136 493 Gat/Aat 0 +IFNGR1 UCSF GRCh37 6 137519586 137519586 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 60 156 0 ENST00000367739.4:c.1052G>A p.Ser351Asn p.S351N ENST00000367739 NM_000416.2 351 aGt/aAt 0 +IFT122 UCSF GRCh37 3 129202342 129202342 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 52 117 0 ENST00000348417.2:c.1668C>T p.Asn556= p.N556= ENST00000348417 NM_052989.2 556 aaC/aaT 0 +IFT140 UCSF GRCh37 16 1614105 1614105 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 38 99 0 ENST00000426508.2:c.1960G>A p.Asp654Asn p.D654N ENST00000426508 NM_014714.3 654 Gac/Aac 0 +IFT172 UCSF GRCh37 2 27677249 27677249 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 79 152 0 ENST00000260570.3:c.3502G>A p.Ala1168Thr p.A1168T ENST00000260570 NM_015662.1 1168 Gct/Act 0 +IGSF6 UCSF GRCh37 16 21658659 21658659 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 70 133 0 ENST00000268389.4:c.222G>A p.Gln74= p.Q74= ENST00000268389 NM_005849.3 74 caG/caA 0 +IGSF8 UCSF GRCh37 1 160065004 160065004 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 35 63 0 ENST00000314485.7:c.97C>T p.Pro33Ser p.P33S ENST00000314485 NM_052868.4 33 Ccc/Tcc 0 +IKBKE UCSF GRCh37 1 206664992 206664992 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 50 109 0 ENST00000367120.3:c.1745G>A p.Ser582Asn p.S582N ENST00000367120 NM_014002.3 582 aGt/aAt 0 +IKBKG UCSF GRCh37 X 153780245 153780245 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 83 170 0 ENST00000369609.5:c.232C>T p.Leu78= p.L78= ENST00000369609 NM_001099856.2 78 Ctg/Ttg 0 +IKZF5 UCSF GRCh37 10 124753348 124753349 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 0 ENST00000368886.5:c.1208dup p.Asn403LysfsTer4 p.N403Kfs*4 ENST00000368886 NM_001271840.1 403 aac/aAac 0 +IL11RA UCSF GRCh37 9 34657129 34657129 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 75 122 0 ENST00000318041.9:c.429C>T p.Arg143= p.R143= ENST00000318041 143 cgC/cgT 0 +IL12RB2 UCSF GRCh37 1 67794023 67794023 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 123 212 0 ENST00000262345.1:c.620G>A p.Gly207Glu p.G207E ENST00000262345 NM_001559.2 207 gGa/gAa 0 +IL17RC UCSF GRCh37 3 9974353 9974353 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 103 1 ENST00000295981.3:c.1662C>T p.Ser554= p.S554= ENST00000295981 NM_153461.3 554 tcC/tcT 0 +IL17RD UCSF GRCh37 3 57136581 57136581 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 55 94 0 ENST00000296318.7:c.905C>T p.Ala302Val p.A302V ENST00000296318 NM_017563.3 302 gCc/gTc 0 +IL18RAP UCSF GRCh37 2 103068538 103068538 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 100 239 0 ENST00000264260.2:c.1697G>A p.Gly566Glu p.G566E ENST00000264260 NM_003853.2 566 gGa/gAa 0 +IL1A UCSF GRCh37 2 113537213 113537213 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 66 142 0 ENST00000263339.3:c.350G>A p.Ser117Asn p.S117N ENST00000263339 NM_000575.3 117 aGc/aAc 0 +IL1RAP UCSF GRCh37 3 190326971 190326971 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 46 113 0 ENST00000072516.3:c.537+1G>A p.X179_splice ENST00000072516 NM_001167929.1 0 +IL1RAPL2 UCSF GRCh37 X 104993017 104993017 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 77 180 0 ENST00000372582.1:c.1113G>A p.Leu371= p.L371= ENST00000372582 NM_017416.1 371 ctG/ctA 0 +IL1RL2 UCSF GRCh37 2 102804367 102804367 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 38 73 0 ENST00000264257.2:c.40C>T p.Pro14Ser p.P14S ENST00000264257 NM_003854.2 14 Cca/Tca 0 +IL21R UCSF GRCh37 16 27448847 27448847 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 53 85 0 ENST00000337929.3:c.191C>T p.Ser64Phe p.S64F ENST00000337929 NM_181078.2 64 tCc/tTc 0 +IL21R UCSF GRCh37 16 27457348 27457348 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 20 61 0 ENST00000337929.3:c.806C>T p.Ala269Val p.A269V ENST00000337929 NM_181078.2 269 gCc/gTc 0 +IL21R UCSF GRCh37 16 27460404 27460404 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 42 57 0 ENST00000337929.3:c.1417G>A p.Val473Ile p.V473I ENST00000337929 NM_181078.2 473 Gtc/Atc 0 +IL23R UCSF GRCh37 1 67724311 67724311 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 101 206 0 ENST00000347310.5:c.1390C>T p.Pro464Ser p.P464S ENST00000347310 NM_144701.2 464 Ccg/Tcg 0 +IL24 UCSF GRCh37 1 207072856 207072856 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 46 112 0 ENST00000294984.2:c.236C>T p.Thr79Ile p.T79I ENST00000294984 NM_006850.3 79 aCt/aTt 0 +IL29 UCSF GRCh37 19 39787105 39787105 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 51 101 0 ENST00000333625.2:c.44G>A p.Gly15Asp p.G15D ENST00000333625 NM_172140.1 15 gGc/gAc 0 +IL2RG UCSF GRCh37 X 70330757 70330757 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 10 56 0 ENST00000374202.2:c.259C>T p.Leu87= p.L87= ENST00000374202 NM_000206.2 87 Ctg/Ttg 0 +IL4R UCSF GRCh37 16 27374306 27374306 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 65 100 0 ENST00000395762.2:c.1633C>T p.Pro545Ser p.P545S ENST00000395762 NM_000418.3 545 Cct/Tct 0 +ILDR1 UCSF GRCh37 3 121713086 121713086 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 34 56 0 ENST00000344209.5:c.721G>A p.Gly241Arg p.G241R ENST00000344209 NM_001199799.1 241 Ggg/Agg 0 +ILF3 UCSF GRCh37 19 10781781 10781781 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 33 76 0 ENST00000590261.1:c.135G>A p.Val45= p.V45= ENST00000590261 45 gtG/gtA 0 +IMP5 UCSF GRCh37 17 43923859 43923859 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 41 106 0 ENST00000329196.5:c.1587G>A p.Gln529= p.Q529= ENST00000329196 NM_175882.2 529 caG/caA 0 +INADL UCSF GRCh37 1 62579725 62579725 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 39 89 0 ENST00000371158.2:c.4462G>A p.Val1488Ile p.V1488I ENST00000371158 NM_176877.2 1488 Gtt/Att 0 +ING1 UCSF GRCh37 13 111371609 111371609 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 32 86 0 ENST00000375774.3:c.599G>A p.Arg200His p.R200H ENST00000375774 NM_005537.4 200 cGc/cAc 0 +INPP4A UCSF GRCh37 2 99152264 99152264 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 108 231 0 ENST00000074304.5:c.343G>A p.Val115Ile p.V115I ENST00000074304 NM_001134224.1 115 Gtc/Atc 0 +INPP5E UCSF GRCh37 9 139333207 139333207 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 11 29 0 ENST00000371712.3:c.665G>A p.Arg222His p.R222H ENST00000371712 NM_019892.4 222 cGc/cAc 0 +INSR UCSF GRCh37 19 7117094 7117094 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 80 149 0 ENST00000302850.5:c.4122G>A p.Leu1374= p.L1374= ENST00000302850 NM_000208.2 1374 ctG/ctA 0 +INSRR UCSF GRCh37 1 156814407 156814407 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 49 85 0 ENST00000368195.3:c.2584G>A p.Val862Met p.V862M ENST00000368195 NM_014215.2 862 Gtg/Atg 0 +INTS10 UCSF GRCh37 8 19703296 19703296 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 43 87 0 ENST00000397977.3:c.1964G>A p.Gly655Glu p.G655E ENST00000397977 NM_018142.2 655 gGa/gAa 0 +INTS3 UCSF GRCh37 1 153745692 153745692 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 130 107 211 0 ENST00000318967.2:c.3075G>A p.Lys1025= p.K1025= ENST00000318967 NM_023015.3 1025 aaG/aaA 0 +INTS5 UCSF GRCh37 11 62416972 62416972 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 76 123 0 ENST00000330574.2:c.580G>A p.Val194Met p.V194M ENST00000330574 NM_030628.1 194 Gtg/Atg 0 +INTS7 UCSF GRCh37 1 212180717 212180717 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 55 121 0 ENST00000366994.3:c.631G>A p.Ala211Thr p.A211T ENST00000366994 NM_001199811.1 211 Gct/Act 0 +INTS8 UCSF GRCh37 8 95877891 95877891 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 404 109 238 0 ENST00000523731.1:c.2234G>A p.Arg745Lys p.R745K ENST00000523731 NM_017864.3 745 aGg/aAg 0 +INTU UCSF GRCh37 4 128565143 128565143 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 83 176 0 ENST00000335251.6:c.614G>A p.Gly205Glu p.G205E ENST00000335251 NM_015693.3 205 gGa/gAa 0 +INTU UCSF GRCh37 4 128564907 128564907 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 78 178 0 ENST00000335251.6:c.378G>A p.Lys126= p.K126= ENST00000335251 NM_015693.3 126 aaG/aaA 0 +INTU UCSF GRCh37 4 128628070 128628070 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 124 101 230 0 ENST00000335251.6:c.2217G>A p.Lys739= p.K739= ENST00000335251 NM_015693.3 739 aaG/aaA 0 +IP6K3 UCSF GRCh37 6 33695944 33695944 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 39 47 0 ENST00000293756.4:c.333G>A p.Gln111= p.Q111= ENST00000293756 NM_054111.4 111 caG/caA 0 +IPCEF1 UCSF GRCh37 6 154533945 154533945 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 23 85 0 ENST00000265198.4:c.493G>A p.Glu165Lys p.E165K ENST00000265198 NM_015553.2 165 Gag/Aag 0 +IPO8 UCSF GRCh37 12 30787141 30787141 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 69 163 0 ENST00000256079.4:c.2775G>A p.Glu925= p.E925= ENST00000256079 NM_006390.3 925 gaG/gaA 0 +IQCH UCSF GRCh37 15 67636400 67636400 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 52 125 0 ENST00000335894.4:c.509-1G>A p.X170_splice ENST00000335894 NM_001031715.2 0 +IQGAP1 UCSF GRCh37 15 91017362 91017362 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 47 114 0 ENST00000268182.5:c.2572C>T p.Leu858Phe p.L858F ENST00000268182 NM_003870.3 858 Ctc/Ttc 0 +IQGAP1 UCSF GRCh37 15 91017182 91017182 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 68 173 0 ENST00000268182.5:c.2488C>T p.Gln830Ter p.Q830* ENST00000268182 NM_003870.3 830 Cag/Tag 0 +IQSEC2 UCSF GRCh37 X 53279582 53279582 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 45 96 0 ENST00000396435.3:c.2176G>A p.Ala726Thr p.A726T ENST00000396435 NM_001111125.2 726 Gct/Act 0 +IQSEC2 UCSF GRCh37 X 53279927 53279927 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 14 26 0 ENST00000396435.3:c.1831G>A p.Asp611Asn p.D611N ENST00000396435 NM_001111125.2 611 Gat/Aat 0 +IRF5 UCSF GRCh37 7 128588798 128588798 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 57 115 0 ENST00000249375.4:c.1423G>A p.Ala475Thr p.A475T ENST00000249375 NM_032643.3 475 Gcc/Acc 0 +IRS1 UCSF GRCh37 2 227663202 227663202 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 73 121 0 ENST00000305123.5:c.253G>A p.Ala85Thr p.A85T ENST00000305123 NM_005544.2 85 Gct/Act 0 +IRX3 UCSF GRCh37 16 54319241 54319241 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 52 89 0 ENST00000329734.3:c.552C>T p.Arg184= p.R184= ENST00000329734 NM_024336.2 184 cgC/cgT 0 +ISLR UCSF GRCh37 15 74468085 74468085 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 42 87 0 ENST00000249842.3:c.886C>T p.Pro296Ser p.P296S ENST00000249842 NM_005545.3 296 Cct/Tct 0 +ITGA2 UCSF GRCh37 5 52377511 52377511 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 31 70 0 ENST00000296585.5:c.3129G>A p.Arg1043= p.R1043= ENST00000296585 NM_002203.3 1043 agG/agA 0 +ITGA2B UCSF GRCh37 17 42466653 42466653 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 99 195 0 ENST00000262407.5:c.188+1G>A p.X63_splice ENST00000262407 NM_000419.3 0 +ITGA6 UCSF GRCh37 2 173338860 173338860 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 41 112 0 ENST00000442250.1:c.970C>T p.His324Tyr p.H324Y ENST00000442250 324 Cac/Tac 0 +ITGA6 UCSF GRCh37 2 173292620 173292620 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 13 45 0 ENST00000442250.1:c.104G>A p.Arg35Gln p.R35Q ENST00000442250 35 cGg/cAg 0 +ITGA8 UCSF GRCh37 10 15573138 15573138 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 130 67 140 0 ENST00000378076.3:c.2893C>T p.Pro965Ser p.P965S ENST00000378076 NM_003638.1 965 Ccc/Tcc 0 +ITGAD UCSF GRCh37 16 31409192 31409192 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 8 26 1 ENST00000389202.2:c.389G>A p.Arg130His p.R130H ENST00000389202 NM_005353.2 130 cGc/cAc 0 +ITGB3 UCSF GRCh37 17 45376743 45376743 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 54 108 0 ENST00000559488.1:c.1760C>T p.Thr587Ile p.T587I ENST00000559488 NM_000212.2 587 aCc/aTc 0 +ITGB3 UCSF GRCh37 17 45369919 45369919 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 55 130 0 ENST00000559488.1:c.1675G>A p.Gly559Arg p.G559R ENST00000559488 NM_000212.2 559 Ggg/Agg 0 +ITIH5 UCSF GRCh37 10 7683969 7683969 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 199 92 185 0 ENST00000256861.6:c.220C>T p.Leu74= p.L74= ENST00000256861 NM_030569.6 74 Ctg/Ttg 0 +ITPK1 UCSF GRCh37 14 93418312 93418312 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 8 17 0 ENST00000267615.6:c.717G>A p.Glu239= p.E239= ENST00000267615 239 gaG/gaA 0 +ITPR1 UCSF GRCh37 3 4725105 4725105 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 140 106 227 0 ENST00000354582.6:c.3197G>A p.Gly1066Asp p.G1066D ENST00000354582 1066 gGc/gAc 0 +ITPR2 UCSF GRCh37 12 26775262 26775262 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 46 116 0 ENST00000381340.3:c.3199C>T p.His1067Tyr p.H1067Y ENST00000381340 NM_002223.2 1067 Cac/Tac 0 +ITPR3 UCSF GRCh37 6 33639817 33639817 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 38 106 0 ENST00000374316.5:c.2740C>T p.Arg914Trp p.R914W ENST00000374316 914 Cgg/Tgg 0 +ITPR3 UCSF GRCh37 6 33646227 33646227 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 21 64 0 ENST00000374316.5:c.3678C>T p.Arg1226= p.R1226= ENST00000374316 1226 cgC/cgT 0 +ITPRIP UCSF GRCh37 10 106074458 106074458 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 37 86 0 ENST00000278071.2:c.1352C>T p.Ala451Val p.A451V ENST00000278071 NM_033397.3 451 gCg/gTg 0 +ITPRIPL1 UCSF GRCh37 2 96993035 96993035 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 54 125 0 ENST00000439118.2:c.666C>T p.Ala222= p.A222= ENST00000439118 NM_001008949.2 222 gcC/gcT 0 +IVNS1ABP UCSF GRCh37 1 185276206 185276206 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 59 163 0 ENST00000367498.3:c.597C>T p.Ile199= p.I199= ENST00000367498 NM_006469.4 199 atC/atT 0 +JHDM1D UCSF GRCh37 7 139829311 139829311 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 64 133 0 ENST00000397560.2:c.541G>A p.Asp181Asn p.D181N ENST00000397560 NM_030647.1 181 Gat/Aat 0 +JMJD1C UCSF GRCh37 10 64974231 64974231 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 83 159 0 ENST00000399262.2:c.1696G>A p.Val566Ile p.V566I ENST00000399262 NM_032776.1 566 Gtc/Atc 0 +JPH2 UCSF GRCh37 20 42744429 42744429 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 20 56 0 ENST00000372980.3:c.1886C>T p.Pro629Leu p.P629L ENST00000372980 NM_020433.4 629 cCc/cTc 0 +JPH3 UCSF GRCh37 16 87677922 87677922 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 11 84 0 ENST00000284262.2:c.441C>T p.Ser147= p.S147= ENST00000284262 NM_020655.3 147 agC/agT 0 +JRK UCSF GRCh37 8 143740347 143740347 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 20 64 0 ENST00000507178.2:n.7464G>A *2488* ENST00000507178 0 +KALRN UCSF GRCh37 3 124418823 124418823 + upstream_gene_variant 5'Flank SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 85 200 0 ENST00000584173 0 +KALRN UCSF GRCh37 3 124117637 124117637 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 64 131 0 ENST00000240874.3:c.2259G>A p.Gln753= p.Q753= ENST00000240874 NM_003947.4 753 caG/caA 0 +KANK3 UCSF GRCh37 19 8398051 8398051 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 10 29 0 ENST00000593649.1:c.1783G>A p.Glu595Lys p.E595K ENST00000593649 595 Gag/Aag 0 +KBTBD4 UCSF GRCh37 11 47598997 47598997 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 76 149 0 ENST00000395288.2:c.555C>T p.His185= p.H185= ENST00000395288 NM_016506.5 185 caC/caT 0 +KCNA3 UCSF GRCh37 1 111216551 111216551 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 47 118 0 ENST00000369769.2:c.881C>T p.Pro294Leu p.P294L ENST00000369769 NM_002232.3 294 cCc/cTc 0 +KCNC1 UCSF GRCh37 11 17757750 17757750 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 27 70 0 ENST00000379472.3:c.201C>T p.Ile67= p.I67= ENST00000379472 NM_004976.4 67 atC/atT 0 +KCNH4 UCSF GRCh37 17 40318550 40318550 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 34 83 0 ENST00000264661.3:c.1605C>T p.Phe535= p.F535= ENST00000264661 NM_012285.2 535 ttC/ttT 0 +KCNH5 UCSF GRCh37 14 63246594 63246594 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 58 116 0 ENST00000322893.7:c.1871C>T p.Ala624Val p.A624V ENST00000322893 NM_139318.4 624 gCc/gTc 0 +KCNH7 UCSF GRCh37 2 163291967 163291967 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 93 183 0 ENST00000332142.5:c.1695G>A p.Trp565Ter p.W565* ENST00000332142 NM_033272.3 565 tgG/tgA 0 +KCNJ12 UCSF GRCh37 17 21319253 21319253 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 31 108 0 ENST00000331718.5:c.599C>T p.Ala200Val p.A200V ENST00000331718 NM_001194958.2 200 gCc/gTc 0 +KCNJ15 UCSF GRCh37 21 39671694 39671694 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 61 118 0 ENST00000328656.4:c.511C>T p.Pro171Ser p.P171S ENST00000328656 NM_002243.4 171 Ccc/Tcc 0 +KCNK16 UCSF GRCh37 6 39285631 39285631 + synonymous_variant Silent SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 22 28 59 0 ENST00000373229.5:c.426C>T p.His142= p.H142= ENST00000373229 NM_032115.3 142 caC/caT 0 +KCNK16 UCSF GRCh37 6 39282934 39282934 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 47 89 0 ENST00000373229.5:c.803-29C>T *268* ENST00000373229 NM_032115.3 0 +KCNN1 UCSF GRCh37 19 18084790 18084790 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 16 25 0 ENST00000222249.9:c.93C>T p.Gly31= p.G31= ENST00000222249 NM_002248.4 31 ggC/ggT 0 +KCNN3 UCSF GRCh37 1 154842381 154842381 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 12 24 0 ENST00000271915.4:c.60G>A p.Lys20= p.K20= ENST00000271915 NM_001204087.1 20 aaG/aaA 0 +KCNN4 UCSF GRCh37 19 44278504 44278504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 10 20 0 ENST00000262888.3:c.523C>T p.Leu175Phe p.L175F ENST00000262888 NM_002250.2 175 Ctc/Ttc 0 +KCNQ1 UCSF GRCh37 11 2591913 2591913 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 0 27 53 0 ENST00000155840.5:c.533C>T p.Ala178Val p.A178V ENST00000155840 NM_000218.2 178 gCc/gTc 0 +KCNQ3 UCSF GRCh37 8 133182671 133182671 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 159 30 102 0 ENST00000388996.4:c.1145C>T p.Ala382Val p.A382V ENST00000388996 NM_004519.3 382 gCc/gTc 0 +KCNQ4 UCSF GRCh37 1 41298711 41298711 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 47 100 1 ENST00000347132.5:c.1539G>A p.Glu513= p.E513= ENST00000347132 NM_004700.3 513 gaG/gaA 0 +KCNS1 UCSF GRCh37 20 43726423 43726423 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 17 44 0 ENST00000306117.1:c.990C>T p.Gly330= p.G330= ENST00000306117 NM_002251.3 330 ggC/ggT 0 +KCNS3 UCSF GRCh37 2 18112819 18112819 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 58 142 0 ENST00000304101.4:c.544C>T p.Leu182= p.L182= ENST00000304101 NM_002252.3 182 Ctg/Ttg 0 +KCNT1 UCSF GRCh37 9 138646990 138646990 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 15 38 0 ENST00000488444.2:c.458G>A p.Arg153Lys p.R153K ENST00000488444 153 aGa/aAa 0 +KCNV1 UCSF GRCh37 8 110980478 110980478 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 198 68 161 0 ENST00000297404.1:c.1342C>T p.Arg448Cys p.R448C ENST00000297404 NM_014379.2 448 Cgt/Tgt 0 +KCNV2 UCSF GRCh37 9 2717784 2717784 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 50 109 0 ENST00000382082.3:c.45C>T p.Pro15= p.P15= ENST00000382082 NM_133497.3 15 ccC/ccT 0 +KCTD9 UCSF GRCh37 8 25303750 25303750 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 86 157 1 ENST00000221200.4:c.65G>A p.Gly22Glu p.G22E ENST00000221200 NM_017634.3 22 gGa/gAa 0 +KDM5A UCSF GRCh37 12 430192 430192 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 106 204 0 ENST00000399788.2:c.2510C>T p.Pro837Leu p.P837L ENST00000399788 NM_001042603.1 837 cCg/cTg 0 +KDM5A UCSF GRCh37 12 443525 443525 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 130 89 233 0 ENST00000399788.2:c.1372C>T p.His458Tyr p.H458Y ENST00000399788 NM_001042603.1 458 Cat/Tat 0 +KDM5C UCSF GRCh37 X 53222334 53222334 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 25 45 0 ENST00000375401.3:c.4498G>A p.Glu1500Lys p.E1500K ENST00000375401 NM_004187.3 1500 Gag/Aag 0 +KIAA0100 UCSF GRCh37 17 26965374 26965374 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 61 123 0 ENST00000528896.2:c.1408C>T p.Leu470Phe p.L470F ENST00000528896 NM_014680.3 470 Ctc/Ttc 0 +KIAA0100 UCSF GRCh37 17 26948142 26948142 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 68 159 0 ENST00000528896.2:c.5106G>A p.Arg1702= p.R1702= ENST00000528896 NM_014680.3 1702 cgG/cgA 0 +KIAA0182 UCSF GRCh37 16 85687940 85687940 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 16 45 0 ENST00000253458.7:c.483G>A p.Pro161= p.P161= ENST00000253458 NM_014615.3 161 ccG/ccA 0 +KIAA0247 UCSF GRCh37 14 70175407 70175407 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 51 108 0 ENST00000342745.4:c.472G>A p.Val158Ile p.V158I ENST00000342745 NM_014734.3 158 Gta/Ata 0 +KIAA0415 UCSF GRCh37 7 4827833 4827833 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 8 13 0 ENST00000348624.4:c.1503G>A p.Arg501= p.R501= ENST00000348624 NM_014855.2 501 agG/agA 0 +KIAA0907 UCSF GRCh37 1 155884103 155884103 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 36 69 0 ENST00000368321.3:c.1654G>A p.Ala552Thr p.A552T ENST00000368321 NM_014949.2 552 Gcc/Acc 0 +KIAA0922 UCSF GRCh37 4 154512343 154512343 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 68 167 0 ENST00000409663.3:c.1806G>A p.Arg602= p.R602= ENST00000409663 NM_015196.3 602 agG/agA 0 +KIAA0947 UCSF GRCh37 5 5443358 5443358 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 21 83 0 ENST00000296564.7:c.386+1G>A p.X129_splice ENST00000296564 NM_015325.2 0 +KIAA0947 UCSF GRCh37 5 5461667 5461667 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 142 128 226 0 ENST00000296564.7:c.2220G>A p.Arg740= p.R740= ENST00000296564 NM_015325.2 740 cgG/cgA 0 +KIAA1024 UCSF GRCh37 15 79750717 79750717 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 84 160 0 ENST00000305428.3:c.2228G>A p.Gly743Asp p.G743D ENST00000305428 NM_015206.2 743 gGc/gAc 0 +KIAA1107 UCSF GRCh37 1 92646067 92646067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 72 186 0 ENST00000370378.4:c.1513C>T p.Pro505Ser p.P505S ENST00000370378 NM_015237.2 505 Cct/Tct 0 +KIAA1161 UCSF GRCh37 9 34372612 34372612 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 16 25 0 ENST00000297625.7:c.228C>T p.Val76= p.V76= ENST00000297625 NM_020702.3 76 gtC/gtT 0 +KIAA1210 UCSF GRCh37 X 118220604 118220604 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 113 189 0 ENST00000402510.2:c.4589G>A p.Gly1530Glu p.G1530E ENST00000402510 NM_020721.1 1530 gGg/gAg 0 +KIAA1217 UCSF GRCh37 10 24508627 24508627 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 54 148 0 ENST00000376454.3:c.143C>T p.Ser48Phe p.S48F ENST00000376454 NM_019590.3 48 tCt/tTt 0 +KIAA1239 UCSF GRCh37 4 37445481 37445481 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 121 196 0 ENST00000309447.5:c.1871G>A p.Arg624Lys p.R624K ENST00000309447 NM_001144990.1 624 aGa/aAa 0 +KIAA1310 UCSF GRCh37 2 97279305 97279305 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 130 115 207 0 ENST00000431828.1:c.715G>A p.Ala239Thr p.A239T ENST00000431828 239 Gct/Act 0 +KIAA1462 UCSF GRCh37 10 30336638 30336638 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 144 68 112 0 ENST00000375377.1:c.104C>T p.Thr35Ile p.T35I ENST00000375377 NM_020848.2 35 aCt/aTt 0 +KIAA1522 UCSF GRCh37 1 33236702 33236702 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 52 86 0 ENST00000373480.1:c.1745C>T p.Ala582Val p.A582V ENST00000373480 NM_001198972.1 582 gCc/gTc 0 +KIAA1524 UCSF GRCh37 3 108276236 108276236 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 63 91 0 ENST00000295746.8:c.2039G>A p.Arg680Lys p.R680K ENST00000295746 NM_020890.2 680 aGa/aAa 0 +KIAA1598 UCSF GRCh37 10 118666174 118666174 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 161 62 236 0 ENST00000355371.4:c.1444C>T p.Arg482Cys p.R482C ENST00000355371 NM_001258299.1 482 Cgt/Tgt 0 +KIAA1609 UCSF GRCh37 16 84520414 84520414 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 56 98 0 ENST00000343629.6:c.781G>A p.Glu261Lys p.E261K ENST00000343629 NM_020947.3 261 Gag/Aag 0 +KIAA1614 UCSF GRCh37 1 180885831 180885831 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 68 97 0 ENST00000367588.4:c.592G>A p.Asp198Asn p.D198N ENST00000367588 NM_020950.1 198 Gac/Aac 0 +KIAA1644 UCSF GRCh37 22 44692584 44692584 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 73 140 0 ENST00000381176.4:c.249C>T p.Asn83= p.N83= ENST00000381176 NM_001099294.1 83 aaC/aaT 0 +KIAA1683 UCSF GRCh37 19 18377737 18377737 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 32 58 0 ENST00000600328.3:c.613C>T p.Pro205Ser p.P205S ENST00000600328 205 Ccc/Tcc 0 +KIAA1751 UCSF GRCh37 1 1918471 1918471 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 37 75 0 ENST00000270720.7:n.456G>A *152* ENST00000270720 0 +KIAA1755 UCSF GRCh37 20 36841641 36841641 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 27 57 0 ENST00000279024.4:c.3406G>A p.Ala1136Thr p.A1136T ENST00000279024 NM_001029864.1 1136 Gct/Act 0 +KIAA1755 UCSF GRCh37 20 36870139 36870139 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 74 154 0 ENST00000279024.4:c.394G>A p.Asp132Asn p.D132N ENST00000279024 NM_001029864.1 132 Gac/Aac 0 +KIAA1984 UCSF GRCh37 9 139693644 139693644 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 11 52 0 ENST00000338005.6:c.161G>A p.Arg54His p.R54H ENST00000338005 NM_001039374.4 54 cGc/cAc 0 +KIAA1984 UCSF GRCh37 9 139701056 139701056 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 66 75 0 ENST00000338005.6:c.1210C>T p.Leu404= p.L404= ENST00000338005 NM_001039374.4 404 Ctg/Ttg 0 +KIAA2022 UCSF GRCh37 X 73962350 73962350 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 46 114 0 ENST00000055682.6:c.2042G>A p.Gly681Asp p.G681D ENST00000055682 NM_001008537.2 681 gGt/gAt 0 +KIDINS220 UCSF GRCh37 2 8916981 8916981 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 70 136 0 ENST00000256707.3:c.2745C>T p.Arg915= p.R915= ENST00000256707 NM_020738.2 915 cgC/cgT 0 +KIF14 UCSF GRCh37 1 200587142 200587142 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 113 229 0 ENST00000367350.4:c.710C>T p.Thr237Met p.T237M ENST00000367350 NM_014875.2 237 aCg/aTg 0 +KIF14 UCSF GRCh37 1 200549469 200549469 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 50 130 0 ENST00000367350.4:c.3378G>A p.Arg1126= p.R1126= ENST00000367350 NM_014875.2 1126 cgG/cgA 0 +KIF14 UCSF GRCh37 1 200572392 200572392 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 75 182 0 ENST00000367350.4:c.1941G>A p.Arg647= p.R647= ENST00000367350 NM_014875.2 647 agG/agA 0 +KIF18B UCSF GRCh37 17 43012728 43012728 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 35 69 0 ENST00000593135.1:c.370G>A p.Gly124Arg p.G124R ENST00000593135 NM_001265577.1 124 Ggg/Agg 0 +KIF19 UCSF GRCh37 17 72350339 72350339 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 59 74 0 ENST00000389916.4:c.2347G>A p.Val783Met p.V783M ENST00000389916 NM_153209.3 783 Gtg/Atg 0 +KIF1B UCSF GRCh37 1 10384913 10384913 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 76 162 0 ENST00000377086.1:c.2635C>T p.Pro879Ser p.P879S ENST00000377086 879 Ccc/Tcc 0 +KIF1C UCSF GRCh37 17 4910581 4910581 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 22 32 0 ENST00000320785.5:c.1359G>A p.Glu453= p.E453= ENST00000320785 NM_006612.5 453 gaG/gaA 0 +KIF20B UCSF GRCh37 10 91477410 91477410 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 71 193 0 ENST00000371728.3:c.1202G>A p.Gly401Glu p.G401E ENST00000371728 NM_001284259.1 401 gGg/gAg 0 +KIF25 UCSF GRCh37 6 168445564 168445564 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 53 122 0 ENST00000354419.2:c.1043C>T p.Ala348Val p.A348V ENST00000354419 NM_030615.2 348 gCa/gTa 0 +KIF26B UCSF GRCh37 1 245850229 245850229 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 55 85 0 ENST00000407071.2:c.3944C>T p.Ala1315Val p.A1315V ENST00000407071 NM_018012.3 1315 gCc/gTc 0 +KIF27 UCSF GRCh37 9 86495271 86495271 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 358 125 352 0 ENST00000297814.2:c.2584G>A p.Glu862Lys p.E862K ENST00000297814 NM_017576.2 862 Gaa/Aaa 0 +KIF4B UCSF GRCh37 5 154393942 154393942 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 128 102 252 0 ENST00000435029.4:c.523G>A p.Gly175Arg p.G175R ENST00000435029 NM_001099293.1 175 Gga/Aga 0 +KIF4B UCSF GRCh37 5 154396999 154396999 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 52 142 0 ENST00000435029.4:c.3580G>A p.Glu1194Lys p.E1194K ENST00000435029 NM_001099293.1 1194 Gag/Aag 0 +KIF6 UCSF GRCh37 6 39507857 39507857 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 140 105 193 0 ENST00000287152.7:c.1567C>T p.Arg523Ter p.R523* ENST00000287152 NM_145027.4 523 Cga/Tga 0 +KIF7 UCSF GRCh37 15 90188645 90188645 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 39 54 0 ENST00000394412.3:c.1960C>T p.Arg654Cys p.R654C ENST00000394412 NM_198525.2 654 Cgc/Tgc 0 +KIRREL3 UCSF GRCh37 11 126870381 126870381 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 11 36 0 ENST00000525144.2:c.25C>T p.Leu9Phe p.L9F ENST00000525144 NM_032531.3 9 Ctc/Ttc 0 +KIRREL3 UCSF GRCh37 11 126294874 126294874 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 38 0 ENST00000525144.2:c.1938C>T p.His646= p.H646= ENST00000525144 NM_032531.3 646 caC/caT 0 +KL UCSF GRCh37 13 33591182 33591182 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 15 16 0 ENST00000380099.3:c.604G>A p.Asp202Asn p.D202N ENST00000380099 NM_004795.3 202 Gac/Aac 0 +KL UCSF GRCh37 13 33635449 33635449 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 54 171 0 ENST00000380099.3:c.2233G>A p.Asp745Asn p.D745N ENST00000380099 NM_004795.3 745 Gac/Aac 0 +KLB UCSF GRCh37 4 39450107 39450107 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 72 164 0 ENST00000257408.4:c.2936C>T p.Thr979Ile p.T979I ENST00000257408 NM_175737.3 979 aCc/aTc 0 +KLB UCSF GRCh37 4 39436095 39436095 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 97 172 0 ENST00000257408.4:c.1091G>A p.Arg364Lys p.R364K ENST00000257408 NM_175737.3 364 aGa/aAa 0 +KLC1 UCSF GRCh37 14 104129146 104129146 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 49 75 0 ENST00000348520.6:c.679G>A p.Gly227Arg p.G227R ENST00000348520 NM_182923.3 227 Ggg/Agg 0 +KLC2 UCSF GRCh37 11 66026132 66026132 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 22 86 0 ENST00000316924.5:c.67G>A p.Ala23Thr p.A23T ENST00000316924 NM_022822.2 23 Gct/Act 0 +KLF15 UCSF GRCh37 3 126071339 126071339 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 36 71 0 ENST00000296233.3:c.427G>A p.Glu143Lys p.E143K ENST00000296233 NM_014079.3 143 Gag/Aag 0 +KLHL1 UCSF GRCh37 13 70549775 70549775 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 76 194 0 ENST00000377844.4:c.657G>A p.Gly219= p.G219= ENST00000377844 NM_020866.2 219 ggG/ggA 0 +KLHL11 UCSF GRCh37 17 40010205 40010205 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 113 161 0 ENST00000319121.3:c.1914G>A p.Arg638= p.R638= ENST00000319121 NM_018143.1 638 agG/agA 0 +KLHL13 UCSF GRCh37 X 117044028 117044028 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 64 143 0 ENST00000262820.3:c.602G>A p.Arg201Gln p.R201Q ENST00000262820 NM_033495.3 201 cGg/cAg 0 +KLHL21 UCSF GRCh37 1 6659327 6659327 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 28 56 0 ENST00000377658.4:c.1207G>A p.Glu403Lys p.E403K ENST00000377658 NM_014851.2 403 Gag/Aag 0 +KLHL3 UCSF GRCh37 5 136974757 136974757 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 25 62 0 ENST00000309755.4:c.1104C>T p.Asp368= p.D368= ENST00000309755 NM_017415.2 368 gaC/gaT 0 +KLHL30 UCSF GRCh37 2 239056482 239056482 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 18 43 0 ENST00000409223.1:c.1158C>T p.Thr386= p.T386= ENST00000409223 386 acC/acT 0 +KLHL33 UCSF GRCh37 14 20897381 20897381 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 21 51 0 ENST00000344581.4:c.1229G>A p.Gly410Asp p.G410D ENST00000344581 NM_001109997.2 410 gGc/gAc 0 +KLHL8 UCSF GRCh37 4 88106778 88106778 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 74 153 0 ENST00000273963.5:c.390C>T p.Leu130= p.L130= ENST00000273963 NM_020803.3 130 ctC/ctT 0 +KLK13 UCSF GRCh37 19 51563773 51563773 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 39 113 0 ENST00000595793.1:c.156C>T p.Ala52= p.A52= ENST00000595793 NM_015596.1 52 gcC/gcT 0 +KLK4 UCSF GRCh37 19 51411834 51411834 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 57 129 0 ENST00000324041.1:c.475+1G>A p.X159_splice ENST00000324041 NM_004917.3 0 +KLK8 UCSF GRCh37 19 51501085 51501085 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 51 142 1 ENST00000600767.1:c.549G>A p.Lys183= p.K183= ENST00000600767 183 aaG/aaA 0 +KLRG2 UCSF GRCh37 7 139168313 139168313 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 10 25 0 ENST00000340940.4:c.76G>A p.Val26Ile p.V26I ENST00000340940 NM_198508.2 26 Gtc/Atc 0 +KNTC1 UCSF GRCh37 12 123065191 123065191 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 62 144 0 ENST00000333479.7:c.2956C>T p.Leu986= p.L986= ENST00000333479 NM_014708.4 986 Cta/Tta 0 +KNTC1 UCSF GRCh37 12 123105155 123105155 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 129 84 196 0 ENST00000333479.7:c.6279G>A p.Lys2093= p.K2093= ENST00000333479 NM_014708.4 2093 aaG/aaA 0 +KPRP UCSF GRCh37 1 152733324 152733324 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 87 146 0 ENST00000606109.1:c.1260G>A p.Pro420= p.P420= ENST00000606109 420 ccG/ccA 0 +KPTN UCSF GRCh37 19 47979872 47979872 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 12 43 0 ENST00000338134.3:c.1099C>T p.Leu367= p.L367= ENST00000338134 NM_007059.2 367 Ctg/Ttg 0 +KREMEN2 UCSF GRCh37 16 3014543 3014543 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 17 49 0 ENST00000303746.5:c.22G>A p.Gly8Ser p.G8S ENST00000303746 8 Ggc/Agc 0 +KRT16 UCSF GRCh37 17 39766220 39766220 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 14 26 0 ENST00000301653.4:c.1389C>T p.Ser463= p.S463= ENST00000301653 NM_005557.3 463 agC/agT 0 +KRT17 UCSF GRCh37 17 39777062 39777062 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 82 148 0 ENST00000311208.8:c.1030G>A p.Gly344Arg p.G344R ENST00000311208 NM_000422.2 344 Ggg/Agg 0 +KRT23 UCSF GRCh37 17 39092689 39092689 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 62 130 0 ENST00000209718.3:c.167G>A p.Gly56Glu p.G56E ENST00000209718 NM_015515.3 56 gGa/gAa 0 +KRT38 UCSF GRCh37 17 39596466 39596466 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 46 123 0 ENST00000246646.3:c.522G>A p.Arg174= p.R174= ENST00000246646 NM_006771.3 174 agG/agA 0 +KRT5 UCSF GRCh37 12 52913654 52913654 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 87 143 0 ENST00000252242.4:c.427G>A p.Val143Ile p.V143I ENST00000252242 NM_000424.3 143 Gtc/Atc 0 +KRT78 UCSF GRCh37 12 53233613 53233613 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 70 90 0 ENST00000304620.4:c.1203C>T p.Ser401= p.S401= ENST00000304620 NM_173352.2 401 agC/agT 0 +KRT8 UCSF GRCh37 12 53292248 53292248 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 17 62 0 ENST00000293308.6:c.1258G>A p.Ala420Thr p.A420T ENST00000293308 NM_002273.3 420 Gca/Aca 0 +KRTAP4-9 UCSF GRCh37 17 39261982 39261982 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 54 81 0 ENST00000391415.1:c.342C>T p.Cys114= p.C114= ENST00000391415 NM_001146041.1 114 tgC/tgT 0 +KRTAP6-3 UCSF GRCh37 21 31964836 31964836 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 80 176 1 ENST00000391624.1:c.51C>T p.Cys17= p.C17= ENST00000391624 NM_181605.3 17 tgC/tgT 0 +KSR2 UCSF GRCh37 12 118198996 118198996 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 46 72 0 ENST00000339824.5:c.806C>T p.Thr269Ile p.T269I ENST00000339824 269 aCc/aTc 0 +LAD1 UCSF GRCh37 1 201355974 201355974 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 101 164 0 ENST00000391967.2:c.515G>A p.Gly172Glu p.G172E ENST00000391967 NM_005558.3 172 gGg/gAg 0 +LAMA2 UCSF GRCh37 6 129687384 129687384 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P10_Rec Untested WXS Illumina HiSeq 41 0 ENST00000421865.2:c.4739del p.Gly1580AlafsTer15 p.G1580Afs*15 ENST00000421865 NM_001079823.1 1580 Ggc/gc 0 +LAMA2 UCSF GRCh37 6 129714201 129714201 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 63 170 0 ENST00000421865.2:c.5246C>T p.Ala1749Val p.A1749V ENST00000421865 NM_001079823.1 1749 gCc/gTc 0 +LAMA3 UCSF GRCh37 18 21395538 21395538 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 41 120 0 ENST00000313654.9:c.2047+1G>A p.X683_splice ENST00000313654 NM_198129.1 0 +LAMA4 UCSF GRCh37 6 112499418 112499418 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 65 101 0 ENST00000230538.7:c.1094G>A p.Arg365Lys p.R365K ENST00000230538 NM_001105206.2 365 aGa/aAa 0 +LAMA4 UCSF GRCh37 6 112460974 112460974 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 76 169 0 ENST00000230538.7:c.3090C>T p.Ser1030= p.S1030= ENST00000230538 NM_001105206.2 1030 tcC/tcT 0 +LAMA5 UCSF GRCh37 20 60889928 60889928 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 48 66 0 ENST00000252999.3:c.8123C>T p.Ala2708Val p.A2708V ENST00000252999 NM_005560.4 2708 gCc/gTc 0 +LAMB1 UCSF GRCh37 7 107594095 107594095 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 75 146 0 ENST00000222399.6:c.2959C>T p.Pro987Ser p.P987S ENST00000222399 NM_002291.2 987 Cca/Tca 0 +LAMB1 UCSF GRCh37 7 107575896 107575896 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 95 204 0 ENST00000222399.6:c.4152G>A p.Lys1384= p.K1384= ENST00000222399 NM_002291.2 1384 aaG/aaA 0 +LAMB3 UCSF GRCh37 1 209800835 209800835 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 31 63 0 ENST00000356082.4:c.1378C>T p.Pro460Ser p.P460S ENST00000356082 NM_000228.2 460 Ccc/Tcc 0 +LAMC2 UCSF GRCh37 1 183197740 183197740 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 68 129 0 ENST00000264144.4:c.1700C>T p.Ala567Val p.A567V ENST00000264144 NM_005562.2 567 gCa/gTa 0 +LAMC3 UCSF GRCh37 9 133932472 133932472 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.010,1000g2011may_all_0.0351,snp132_rs61737720 P10_Rec Untested WXS Illumina HiSeq 120 61 111 0 ENST00000361069.4:c.2096G>A p.Gly699Asp p.G699D ENST00000361069 NM_006059.3 699 gGt/gAt 0 +LAP3 UCSF GRCh37 4 17608484 17608484 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 58 156 0 ENST00000226299.4:c.1293G>A p.Arg431= p.R431= ENST00000226299 NM_015907.2 431 agG/agA 0 +LARS UCSF GRCh37 5 145508612 145508612 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 36 104 0 ENST00000394434.2:c.2698C>T p.Gln900Ter p.Q900* ENST00000394434 NM_020117.9 900 Cag/Tag 0 +LAS1L UCSF GRCh37 X 64748194 64748194 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 6 26 0 ENST00000374811.3:c.902C>T p.Ser301Phe p.S301F ENST00000374811 NM_031206.4 301 tCc/tTc 0 +LATS1 UCSF GRCh37 6 149997779 149997779 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 42 71 0 ENST00000253339.5:c.2688G>A p.Arg896= p.R896= ENST00000253339 896 cgG/cgA 0 +LAX1 UCSF GRCh37 1 203743526 203743526 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 85 140 0 ENST00000442561.2:c.914G>A p.Ser305Asn p.S305N ENST00000442561 NM_017773.3 305 aGc/aAc 0 +LCE3E UCSF GRCh37 1 152538436 152538436 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 95 161 0 ENST00000368789.1:c.249C>T p.Gly83= p.G83= ENST00000368789 NM_178435.3 83 ggC/ggT 0 +LCK UCSF GRCh37 1 32740015 32740015 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 65 108 0 ENST00000336890.5:c.85C>T p.Pro29Ser p.P29S ENST00000336890 NM_005356.3 29 Cca/Tca 0 +LCT UCSF GRCh37 2 136561679 136561679 + missense_variant Missense_Mutation SNP T T A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 41 120 0 ENST00000264162.2:c.4484A>T p.Asp1495Val p.D1495V ENST00000264162 NM_002299.2 1495 gAc/gTc 0 +LDB2 UCSF GRCh37 4 16504426 16504426 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 117 104 198 0 ENST00000304523.5:c.962C>T p.Thr321Ile p.T321I ENST00000304523 NM_001290.3 321 aCt/aTt 0 +LDB2 UCSF GRCh37 4 16504319 16504319 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 110 192 0 ENST00000304523.5:c.1069C>T p.Pro357Ser p.P357S ENST00000304523 NM_001290.3 357 Ccc/Tcc 0 +LDB3 UCSF GRCh37 10 88441418 88441418 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 43 79 0 ENST00000361373.4:c.547C>T p.Pro183Ser p.P183S ENST00000361373 NM_007078.2 183 Cca/Tca 0 +LEAP2 UCSF GRCh37 5 132209757 132209757 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 52 131 0 ENST00000296877.2:c.173C>T p.Ser58Phe p.S58F ENST00000296877 NM_052971.2 58 tCt/tTt 0 +LEPREL1 UCSF GRCh37 3 189706695 189706695 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 78 183 0 ENST00000319332.5:c.955+1G>A p.X319_splice ENST00000319332 NM_018192.3 0 +LGALS9B UCSF GRCh37 17 20361598 20361598 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 48 243 0 ENST00000423676.3:c.231G>A p.Arg77= p.R77= ENST00000423676 77 agG/agA 0 +LGR5 UCSF GRCh37 12 71834027 71834027 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 42 47 0 ENST00000266674.5:c.167G>A p.Gly56Glu p.G56E ENST00000266674 NM_001277226.1 56 gGg/gAg 0 +LHFPL2 UCSF GRCh37 5 77805969 77805969 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 54 113 0 ENST00000380345.2:c.68C>T p.Ala23Val p.A23V ENST00000380345 NM_005779.2 23 gCc/gTc 0 +LHX2 UCSF GRCh37 9 126777518 126777518 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 79 141 0 ENST00000373615.4:c.441C>T p.Asn147= p.N147= ENST00000373615 NM_004789.3 147 aaC/aaT 0 +LHX4 UCSF GRCh37 1 180243477 180243477 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 96 190 0 ENST00000263726.2:c.936G>A p.Gln312= p.Q312= ENST00000263726 NM_033343.3 312 caG/caA 0 +LILRB3 UCSF GRCh37 19 54725769 54725769 + missense_variant Missense_Mutation SNP A A T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 31 109 0 ENST00000245620.9:c.589T>A p.Tyr197Asn p.Y197N ENST00000245620 197 Tat/Aat 0 +LIMA1 UCSF GRCh37 12 50615987 50615987 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 106 192 0 ENST00000341247.4:c.447G>A p.Glu149= p.E149= ENST00000341247 NM_016357.4 149 gaG/gaA 0 +LLGL1 UCSF GRCh37 17 18137478 18137478 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 24 29 0 ENST00000316843.4:c.703C>T p.Leu235= p.L235= ENST00000316843 NM_004140.3 235 Ctg/Ttg 0 +LMBRD1 UCSF GRCh37 6 70411348 70411348 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 17 63 0 ENST00000370577.3:c.1070C>T p.Pro357Leu p.P357L ENST00000370577 NM_018368.3 357 cCt/cTt 0 +LNP1 UCSF GRCh37 3 100148694 100148694 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 56 119 0 ENST00000383693.3:c.121G>A p.Ala41Thr p.A41T ENST00000383693 NM_001085451.1 41 Gcc/Acc 0 +LOC100129924 UCSF GRCh37 1 43255568 43255568 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 59 110 0 ENST00000421630.1:c.89G>A p.Val31Met p.V31M ENST00000421630 NM_001242750.1 31 Gtg/Atg 0 +LOC120824 UCSF GRCh37 11 49002870 49002870 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 112 214 0 ENST00000534741.1:n.378C>T *126* ENST00000534741 0 +LOC388946 UCSF GRCh37 2 46711561 46711561 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 121 112 231 0 ENST00000434431.1:c.656C>T p.Ser219Leu p.S219L ENST00000434431 NM_001145051.2 219 tCa/tTa 0 +LOH12CR1 UCSF GRCh37 12 12510410 12510410 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 15 30 0 ENST00000314565.4:c.25G>A p.Ala9Thr p.A9T ENST00000314565 NM_058169.3 9 Gcc/Acc 0 +LONP2 UCSF GRCh37 16 48278417 48278417 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 9 20 0 ENST00000285737.4:c.118C>T p.Gln40Ter p.Q40* ENST00000285737 NM_031490.2 40 Cag/Tag 0 +LOX UCSF GRCh37 5 121413366 121413366 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 10 11 0 ENST00000231004.4:c.315G>A p.Arg105= p.R105= ENST00000231004 NM_002317.5 105 cgG/cgA 0 +LOXHD1 UCSF GRCh37 18 44159706 44159706 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 37 83 0 ENST00000398722.4:c.862G>A p.Gly288Ser p.G288S ENST00000398722 288 Ggt/Agt 0 +LOXHD1 UCSF GRCh37 18 44122802 44122802 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 29 112 0 ENST00000300591.6:c.303G>A p.Lys101= p.K101= ENST00000300591 NM_001145472.2 101 aaG/aaA 0 +LOXHD1 UCSF GRCh37 18 44104875 44104875 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 4 30 0 ENST00000300591.6:c.1203C>T p.Asp401= p.D401= ENST00000300591 NM_001145472.2 401 gaC/gaT 0 +LPXN UCSF GRCh37 11 58318693 58318693 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 40 85 0 ENST00000395074.2:c.331G>A p.Ala111Thr p.A111T ENST00000395074 NM_004811.2 111 Gca/Aca 0 +LRBA UCSF GRCh37 4 151408963 151408963 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001 P10_Rec Untested WXS Illumina HiSeq 63 49 123 0 ENST00000357115.3:c.6505G>A p.Asp2169Asn p.D2169N ENST00000357115 NM_006726.4 2169 Gac/Aac 0 +LRBA UCSF GRCh37 4 151203777 151203777 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 53 110 0 ENST00000357115.3:c.8174C>T p.Ser2725Phe p.S2725F ENST00000357115 NM_006726.4 2725 tCc/tTc 0 +LRCH4 UCSF GRCh37 7 100173932 100173932 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 21 39 0 ENST00000310300.6:c.1567G>A p.Asp523Asn p.D523N ENST00000310300 NM_002319.3 523 Gac/Aac 0 +LRFN3 UCSF GRCh37 19 36430445 36430445 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 15 33 0 ENST00000246529.3:c.118C>T p.Pro40Ser p.P40S ENST00000246529 NM_024509.1 40 Ccc/Tcc 0 +LRG1 UCSF GRCh37 19 4538787 4538787 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 42 72 0 ENST00000306390.6:c.209C>T p.Thr70Ile p.T70I ENST00000306390 NM_052972.2 70 aCc/aTc 0 +LRP1B UCSF GRCh37 2 141259338 141259338 + missense_variant Missense_Mutation SNP C C T snp132_rs77813209 P10_Rec Untested WXS Illumina HiSeq 77 74 178 0 ENST00000389484.3:c.8768G>A p.Arg2923Lys p.R2923K ENST00000389484 NM_018557.2 2923 aGa/aAa 0 +LRP2 UCSF GRCh37 2 170101379 170101379 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 72 198 0 ENST00000263816.3:c.3254G>A p.Arg1085His p.R1085H ENST00000263816 NM_004525.2 1085 cGc/cAc 0 +LRRC24 UCSF GRCh37 8 145748767 145748767 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 20 35 0 ENST00000529415.2:c.634C>T p.Leu212= p.L212= ENST00000529415 212 Ctg/Ttg 0 +LRRC45 UCSF GRCh37 17 79983276 79983276 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 39 126 0 ENST00000306688.3:c.554G>A p.Gly185Asp p.G185D ENST00000306688 NM_144999.2 185 gGc/gAc 0 +LRRC48 UCSF GRCh37 17 17910712 17910712 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 70 152 0 ENST00000313838.8:c.1326+251G>A *442* ENST00000313838 NM_001130090.1 0 +LRRC49 UCSF GRCh37 15 71188259 71188259 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 27 111 0 ENST00000260382.5:c.177C>T p.Asn59= p.N59= ENST00000260382 NM_001199017.1 59 aaC/aaT 0 +LRRC4C UCSF GRCh37 11 40137279 40137279 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 101 206 0 ENST00000278198.2:c.564C>T p.Ile188= p.I188= ENST00000278198 188 atC/atT 0 +LRRC4C UCSF GRCh37 11 40137585 40137585 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 5 63 133 0 ENST00000278198.2:c.258C>T p.Asn86= p.N86= ENST00000278198 86 aaC/aaT 0 +LRRIQ1 UCSF GRCh37 12 85546078 85546078 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 65 159 0 ENST00000393217.2:c.4350G>A p.Trp1450Ter p.W1450* ENST00000393217 NM_001079910.1 1450 tgG/tgA 0 +LRRIQ4 UCSF GRCh37 3 169540582 169540582 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 73 163 0 ENST00000340806.6:c.873C>T p.Gly291= p.G291= ENST00000340806 NM_001080460.1 291 ggC/ggT 0 +LRRK2 UCSF GRCh37 12 40696608 40696608 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 77 194 0 ENST00000298910.7:c.3514C>T p.Pro1172Ser p.P1172S ENST00000298910 NM_198578.3 1172 Cct/Tct 0 +LRRTM1 UCSF GRCh37 2 80530170 80530170 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 52 111 0 ENST00000295057.3:c.775G>A p.Glu259Lys p.E259K ENST00000295057 NM_178839.4 259 Gag/Aag 0 +LRRTM3 UCSF GRCh37 10 68687617 68687617 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 83 181 0 ENST00000361320.4:c.943G>A p.Glu315Lys p.E315K ENST00000361320 NM_178011.3 315 Gaa/Aaa 0 +LRRTM3 UCSF GRCh37 10 68687235 68687235 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 96 203 0 ENST00000361320.4:c.561C>T p.Asp187= p.D187= ENST00000361320 NM_178011.3 187 gaC/gaT 0 +LRWD1 UCSF GRCh37 7 102108556 102108556 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 14 20 0 ENST00000292616.5:c.726C>T p.Leu242= p.L242= ENST00000292616 NM_152892.1 242 ctC/ctT 0 +LSG1 UCSF GRCh37 3 194387006 194387006 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 65 150 0 ENST00000265245.5:c.360C>T p.Asn120= p.N120= ENST00000265245 NM_018385.2 120 aaC/aaT 0 +LSMD1 UCSF GRCh37 17 7760127 7760127 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 49 100 0 ENST00000575771.1:c.144C>T p.Gly48= p.G48= ENST00000575771 48 ggC/ggT 0 +LTBP1 UCSF GRCh37 2 33623550 33623550 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 58 130 0 ENST00000404816.2:c.5104C>T p.Pro1702Ser p.P1702S ENST00000404816 1702 Cca/Tca 0 +LTK UCSF GRCh37 15 41804429 41804429 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 16 43 0 ENST00000263800.6:c.394G>A p.Ala132Thr p.A132T ENST00000263800 NM_002344.5 132 Gcc/Acc 0 +LTN1 UCSF GRCh37 21 30304865 30304865 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 132 131 227 0 ENST00000361371.5:c.4997G>A p.Gly1666Glu p.G1666E ENST00000361371 1666 gGg/gAg 0 +LTN1 UCSF GRCh37 21 30313628 30313628 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 67 184 0 ENST00000361371.5:c.4396C>T p.Pro1466Ser p.P1466S ENST00000361371 1466 Cca/Tca 0 +LTN1 UCSF GRCh37 21 30316208 30316208 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 70 173 0 ENST00000361371.5:c.4001C>T p.Ser1334Phe p.S1334F ENST00000361371 1334 tCt/tTt 0 +LUZP1 UCSF GRCh37 1 23420637 23420637 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 76 213 0 ENST00000302291.4:c.118G>A p.Ala40Thr p.A40T ENST00000302291 40 Gca/Aca 0 +LY75 UCSF GRCh37 2 160750565 160750565 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 57 186 0 ENST00000263636.4:c.497G>A p.Gly166Glu p.G166E ENST00000263636 NM_002349.3 166 gGg/gAg 0 +LYPD4 UCSF GRCh37 19 42342085 42342085 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 53 121 0 ENST00000330743.3:c.462C>T p.Leu154= p.L154= ENST00000330743 NM_173506.4 154 ctC/ctT 0 +MACF1 UCSF GRCh37 1 39759204 39759204 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 87 211 0 ENST00000372915.3:c.2082C>T p.Ile694= p.I694= ENST00000372915 694 atC/atT 0 +MACF1 UCSF GRCh37 1 39913788 39913788 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 66 152 0 ENST00000372915.3:c.19749C>T p.Asp6583= p.D6583= ENST00000372915 6583 gaC/gaT 0 +MACROD1 UCSF GRCh37 11 63766310 63766310 + splice_region_variant,3_prime_UTR_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 4 21 0 ENST00000255681.6:c.*30G>A p.X10_splice ENST00000255681 NM_014067.3 0 +MAD2L2 UCSF GRCh37 1 11736191 11736191 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 27 58 0 ENST00000235310.3:c.339C>T p.Asp113= p.D113= ENST00000235310 113 gaC/gaT 0 +MAG UCSF GRCh37 19 35793430 35793430 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 41 109 0 ENST00000392213.3:c.1050G>A p.Gln350= p.Q350= ENST00000392213 NM_002361.3 350 caG/caA 0 +MAGEB3 UCSF GRCh37 X 30254867 30254867 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 75 158 0 ENST00000361644.2:c.826G>A p.Gly276Ser p.G276S ENST00000361644 NM_002365.4 276 Ggt/Agt 0 +MAGEB6 UCSF GRCh37 X 26212424 26212424 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 76 211 0 ENST00000379034.1:c.461C>T p.Thr154Ile p.T154I ENST00000379034 NM_173523.2 154 aCt/aTt 0 +MAGED2 UCSF GRCh37 X 54841848 54841848 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 40 41 90 0 ENST00000218439.4:c.1554G>A p.Trp518Ter p.W518* ENST00000218439 518 tgG/tgA 0 +MAGED2 UCSF GRCh37 X 54838651 54838651 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 44 96 0 ENST00000218439.4:c.1052C>T p.Thr351Ile p.T351I ENST00000218439 351 aCc/aTc 0 +MAGI2 UCSF GRCh37 7 77649240 77649240 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 39 50 0 ENST00000354212.4:c.3760G>A p.Val1254Ile p.V1254I ENST00000354212 NM_012301.3 1254 Gta/Ata 0 +MAGI3 UCSF GRCh37 1 113933844 113933844 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 7 15 0 ENST00000307546.9:c.189G>A p.Lys63= p.K63= ENST00000307546 NM_001142782.1 63 aaG/aaA 0 +MAK UCSF GRCh37 6 10791958 10791958 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 64 179 0 ENST00000313243.2:c.1266G>A p.Lys422= p.K422= ENST00000313243 422 aaG/aaA 0 +MAK16 UCSF GRCh37 8 33346598 33346598 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 67 201 0 ENST00000360128.6:c.333G>A p.Gln111= p.Q111= ENST00000360128 NM_032509.3 111 caG/caA 0 +MAL2 UCSF GRCh37 8 120252459 120252459 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 348 107 164 0 ENST00000276681.6:c.358G>A p.Glu120Lys p.E120K ENST00000276681 NM_052886.2 120 Gaa/Aaa 0 +MAMDC4 UCSF GRCh37 9 139748472 139748472 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 135 47 123 0 ENST00000445819.1:c.614C>T p.Thr205Ile p.T205I ENST00000445819 205 aCc/aTc 0 +MAMDC4 UCSF GRCh37 9 139750500 139750500 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 42 96 0 ENST00000445819.1:c.1619G>A p.Gly540Glu p.G540E ENST00000445819 540 gGg/gAg 0 +MAML3 UCSF GRCh37 4 141074079 141074079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 7 23 0 ENST00000509479.2:c.403C>T p.Pro135Ser p.P135S ENST00000509479 NM_018717.4 135 Ccg/Tcg 0 +MAMSTR UCSF GRCh37 19 49218605 49218605 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 22 52 0 ENST00000318083.6:c.339G>A p.Arg113= p.R113= ENST00000318083 113 agG/agA 0 +MAN2B1 UCSF GRCh37 19 12759216 12759216 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 21 52 0 ENST00000456935.2:c.2437G>A p.Val813Met p.V813M ENST00000456935 NM_000528.3 813 Gtg/Atg 0 +MANF UCSF GRCh37 3 51425239 51425239 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 94 193 0 ENST00000528157.1:c.294C>T p.His98= p.H98= ENST00000528157 NM_006010.4 98 caC/caT 0 +MAP1A UCSF GRCh37 15 43819862 43819862 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.0018 P10_Rec Untested WXS Illumina HiSeq 35 49 72 0 ENST00000300231.5:c.6191C>T p.Pro2064Leu p.P2064L ENST00000300231 2064 cCc/cTc 0 +MAP1B UCSF GRCh37 5 71403432 71403432 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 11 16 0 ENST00000296755.7:c.74C>T p.Ser25Leu p.S25L ENST00000296755 NM_005909.3 25 tCg/tTg 0 +MAP1S UCSF GRCh37 19 17838521 17838521 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 19 41 0 ENST00000324096.4:c.2328G>A p.Gly776= p.G776= ENST00000324096 NM_018174.4 776 ggG/ggA 0 +MAP2 UCSF GRCh37 2 210560323 210560323 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 84 151 0 ENST00000360351.4:c.3429G>A p.Glu1143= p.E1143= ENST00000360351 NM_002374.3 1143 gaG/gaA 0 +MAP3K14 UCSF GRCh37 17 43345108 43345108 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 72 179 0 ENST00000344686.2:n.2097C>T *699* ENST00000344686 0 +MAP3K4 UCSF GRCh37 6 161470113 161470113 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 53 132 0 ENST00000392142.4:c.809C>T p.Ala270Val p.A270V ENST00000392142 NM_005922.2 270 gCc/gTc 0 +MAP3K4 UCSF GRCh37 6 161519420 161519420 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 76 177 0 ENST00000392142.4:c.3635C>T p.Ser1212Phe p.S1212F ENST00000392142 NM_005922.2 1212 tCt/tTt 0 +MAP3K9 UCSF GRCh37 14 71199907 71199907 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 50 93 0 ENST00000554752.2:c.2179G>A p.Ala727Thr p.A727T ENST00000554752 NM_001284230.1 727 Gcc/Acc 0 +MAP3K9 UCSF GRCh37 14 71215576 71215576 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 62 149 0 ENST00000554752.2:c.1296G>A p.Glu432= p.E432= ENST00000554752 NM_001284230.1 432 gaG/gaA 0 +MAP4K4 UCSF GRCh37 2 102477371 102477371 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 67 149 0 ENST00000347699.4:c.1789C>T p.Pro597Ser p.P597S ENST00000347699 NM_145687.3 597 Cct/Tct 0 +MAP7D2 UCSF GRCh37 X 20044013 20044013 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 115 222 0 ENST00000379651.3:c.942G>A p.Gly314= p.G314= ENST00000379651 NM_152780.3 314 ggG/ggA 0 +MAPK7 UCSF GRCh37 17 19286515 19286515 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 41 64 0 ENST00000308406.5:c.2422G>A p.Ala808Thr p.A808T ENST00000308406 NM_139033.2 808 Gct/Act 0 +MAPK8IP3 UCSF GRCh37 16 1756385 1756385 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 16 16 0 ENST00000250894.4:c.45C>T p.Tyr15= p.Y15= ENST00000250894 NM_015133.3 15 taC/taT 0 +MARVELD3 UCSF GRCh37 16 71668385 71668385 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 67 102 0 ENST00000268485.3:c.885C>T p.Val295= p.V295= ENST00000268485 NM_052858.5 295 gtC/gtT 0 +MASP1 UCSF GRCh37 3 186961389 186961389 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 83 186 0 ENST00000337774.5:c.1111G>A p.Gly371Arg p.G371R ENST00000337774 NM_001879.5 371 Gga/Aga 0 +MASP2 UCSF GRCh37 1 11094897 11094897 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 18 41 0 ENST00000400897.3:c.1075C>T p.Pro359Ser p.P359S ENST00000400897 NM_006610.3 359 Ccc/Tcc 0 +MAST1 UCSF GRCh37 19 12980027 12980027 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 63 128 0 ENST00000251472.4:c.2921G>A p.Gly974Asp p.G974D ENST00000251472 NM_014975.2 974 gGc/gAc 0 +MAST1 UCSF GRCh37 19 12981740 12981740 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 99 172 0 ENST00000251472.4:c.3106G>A p.Val1036Ile p.V1036I ENST00000251472 NM_014975.2 1036 Gtc/Atc 0 +MAST2 UCSF GRCh37 1 46295118 46295118 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 77 118 0 ENST00000361297.2:c.333G>A p.Gln111= p.Q111= ENST00000361297 NM_015112.2 111 caG/caA 0 +MAST3 UCSF GRCh37 19 18241465 18241465 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 57 136 0 ENST00000262811.6:c.1298C>T p.Ser433Phe p.S433F ENST00000262811 NM_015016.1 433 tCc/tTc 0 +MAST3 UCSF GRCh37 19 18235099 18235099 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 57 80 0 ENST00000262811.6:c.781G>A p.Glu261Lys p.E261K ENST00000262811 NM_015016.1 261 Gag/Aag 0 +MATN4 UCSF GRCh37 20 43927138 43927138 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 54 113 0 ENST00000372754.1:c.1221C>T p.Arg407= p.R407= ENST00000372754 407 cgC/cgT 0 +MC2R UCSF GRCh37 18 13884907 13884907 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 64 106 0 ENST00000327606.3:c.611C>T p.Thr204Ile p.T204I ENST00000327606 NM_000529.2 204 aCc/aTc 0 +MCCC2 UCSF GRCh37 5 70945927 70945927 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 103 214 1 ENST00000340941.6:c.1405C>T p.Arg469Cys p.R469C ENST00000340941 NM_022132.4 469 Cgt/Tgt 0 +MCF2L UCSF GRCh37 13 113741572 113741572 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 23 47 0 ENST00000375608.3:c.2487G>A p.Lys829= p.K829= ENST00000375608 829 aaG/aaA 0 +MCF2L2 UCSF GRCh37 3 183027568 183027568 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 75 150 0 ENST00000328913.3:c.1049G>A p.Gly350Glu p.G350E ENST00000328913 NM_015078.2 350 gGa/gAa 0 +MDN1 UCSF GRCh37 6 90383056 90383056 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 73 148 0 ENST00000369393.3:c.13373C>T p.Ala4458Val p.A4458V ENST00000369393 4458 gCa/gTa 0 +MED12L UCSF GRCh37 3 151148113 151148113 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 51 107 0 ENST00000474524.1:c.6330C>T p.Thr2110= p.T2110= ENST00000474524 NM_053002.4 2110 acC/acT 0 +MED13L UCSF GRCh37 12 116421027 116421027 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 62 135 0 ENST00000281928.3:c.4850G>A p.Ser1617Asn p.S1617N ENST00000281928 NM_015335.4 1617 aGc/aAc 0 +MED13L UCSF GRCh37 12 116443759 116443759 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 52 137 0 ENST00000281928.3:c.2384G>A p.Ser795Asn p.S795N ENST00000281928 NM_015335.4 795 aGt/aAt 0 +MED14 UCSF GRCh37 X 40531161 40531161 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 89 186 0 ENST00000324817.1:c.3085C>T p.His1029Tyr p.H1029Y ENST00000324817 NM_004229.3 1029 Cat/Tat 0 +MED14 UCSF GRCh37 X 40534551 40534551 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 56 139 0 ENST00000324817.1:c.2943C>T p.Asp981= p.D981= ENST00000324817 NM_004229.3 981 gaC/gaT 0 +MED14 UCSF GRCh37 X 40562802 40562802 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 51 103 0 ENST00000324817.1:c.1305C>T p.Leu435= p.L435= ENST00000324817 NM_004229.3 435 ctC/ctT 0 +MED23 UCSF GRCh37 6 131929203 131929203 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 77 152 0 ENST00000368068.3:c.1086G>A p.Gly362= p.G362= ENST00000368068 NM_004830.3 362 ggG/ggA 0 +MEGF11 UCSF GRCh37 15 66420670 66420670 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 17 29 0 ENST00000409699.2:c.72C>T p.Asp24= p.D24= ENST00000409699 24 gaC/gaT 0 +MEI1 UCSF GRCh37 22 42190449 42190449 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 129 232 0 ENST00000401548.3:c.3502C>T p.Leu1168Phe p.L1168F ENST00000401548 NM_152513.3 1168 Ctc/Ttc 0 +MESP1 UCSF GRCh37 15 90294045 90294045 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 8 15 0 ENST00000300057.4:c.418C>T p.Leu140= p.L140= ENST00000300057 NM_018670.3 140 Cta/Tta 0 +METTL10 UCSF GRCh37 10 126454016 126454017 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 0 ENST00000368836.2:c.561dup p.Leu188SerfsTer6 p.L188Sfs*6 ENST00000368836 NM_212554.2 187 ttt/ttTt 0 +METTL3 UCSF GRCh37 14 21971694 21971694 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 62 163 0 ENST00000298717.4:c.345G>A p.Gly115= p.G115= ENST00000298717 NM_019852.3 115 ggG/ggA 0 +METTL4 UCSF GRCh37 18 2547360 2547360 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 68 154 0 ENST00000574538.1:c.1068G>A p.Trp356Ter p.W356* ENST00000574538 NM_022840.3 356 tgG/tgA 0 +MEX3A UCSF GRCh37 1 156047225 156047225 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 16 58 0 ENST00000532414.2:c.703G>A p.Val235Met p.V235M ENST00000532414 NM_001093725.1 235 Gtg/Atg 0 +MFAP3L UCSF GRCh37 4 170913421 170913421 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 71 140 0 ENST00000361618.3:c.338C>T p.Thr113Ile p.T113I ENST00000361618 NM_021647.6 113 aCc/aTc 0 +MFHAS1 UCSF GRCh37 8 8749590 8749590 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 42 78 0 ENST00000276282.6:c.979G>A p.Asp327Asn p.D327N ENST00000276282 NM_004225.2 327 Gat/Aat 0 +MFSD7 UCSF GRCh37 4 680002 680002 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 27 67 0 ENST00000404286.2:c.384C>T p.Phe128= p.F128= ENST00000404286 NM_032219.2 128 ttC/ttT 0 +MGST2 UCSF GRCh37 4 140599723 140599723 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 46 98 0 ENST00000265498.1:c.85G>A p.Ala29Thr p.A29T ENST00000265498 NM_002413.4 29 Gca/Aca 0 +MICAL3 UCSF GRCh37 22 18362124 18362124 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 40 63 0 ENST00000441493.2:c.2241+6520C>T *747* ENST00000441493 NM_015241.2 0 +MINA UCSF GRCh37 3 97686406 97686406 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 38 98 0 ENST00000333396.7:c.32G>A p.Gly11Glu p.G11E ENST00000333396 NM_001042533.2 11 gGg/gAg 0 +MITF UCSF GRCh37 3 69987126 69987126 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 54 124 0 ENST00000448226.2:c.508C>T p.Pro170Ser p.P170S ENST00000448226 170 Cca/Tca 0 +MKRN2 UCSF GRCh37 3 12611623 12611623 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 64 115 0 ENST00000170447.7:c.209C>T p.Ala70Val p.A70V ENST00000170447 NM_014160.4 70 gCc/gTc 0 +MLH1 UCSF GRCh37 3 37090029 37090029 + missense_variant Missense_Mutation SNP C C T snp132_rs63749792 P10_Rec somatic WXS Sanger Illumina HiSeq 9 59 135 0 ENST00000231790.2:c.1918C>T p.Pro640Ser p.P640S ENST00000231790 NM_000249.3 640 Ccc/Tcc 0 +MLKL UCSF GRCh37 16 74706417 74706417 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 91 198 0 ENST00000308807.7:c.1401C>T p.Ser467= p.S467= ENST00000308807 NM_152649.2 467 tcC/tcT 0 +MLL UCSF GRCh37 11 118373395 118373395 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 73 161 0 ENST00000389506.5:c.6779C>T p.Thr2260Ile p.T2260I ENST00000389506 2260 aCt/aTt 0 +MLL2 UCSF GRCh37 12 49443496 49443496 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 60 110 0 ENST00000301067.7:c.3875G>A p.Arg1292His p.R1292H ENST00000301067 NM_003482.3 1292 cGc/cAc 0 +MLL2 UCSF GRCh37 12 49431862 49431862 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 51 122 0 ENST00000301067.7:c.9277C>T p.Pro3093Ser p.P3093S ENST00000301067 NM_003482.3 3093 Ccc/Tcc 0 +MLL2 UCSF GRCh37 12 49436429 49436429 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 46 126 0 ENST00000301067.7:c.5783-1G>A p.X1928_splice ENST00000301067 NM_003482.3 0 +MLL2 UCSF GRCh37 12 49416080 49416080 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 69 116 0 ENST00000301067.7:c.16395G>A p.Leu5465= p.L5465= ENST00000301067 NM_003482.3 5465 ttG/ttA 0 +MLL2 UCSF GRCh37 12 49435948 49435948 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 28 85 0 ENST00000301067.7:c.6033G>A p.Glu2011= p.E2011= ENST00000301067 NM_003482.3 2011 gaG/gaA 0 +MLL3 UCSF GRCh37 7 151851369 151851369 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 66 151 0 ENST00000262189.6:c.12122C>T p.Pro4041Leu p.P4041L ENST00000262189 NM_170606.2 4041 cCt/cTt 0 +MLL3 UCSF GRCh37 7 151884919 151884919 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 73 164 0 ENST00000262189.6:c.4674G>A p.Arg1558= p.R1558= ENST00000262189 NM_170606.2 1558 cgG/cgA 0 +MLL4 UCSF GRCh37 19 36210734 36210734 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 64 138 0 ENST00000420124.1:c.485C>T p.Pro162Leu p.P162L ENST00000420124 162 cCt/cTt 0 +MLLT10 UCSF GRCh37 10 21903804 21903804 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 31 92 0 ENST00000307729.7:c.554C>T p.Ala185Val p.A185V ENST00000307729 185 gCc/gTc 0 +MLLT10 UCSF GRCh37 10 21962612 21962612 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 221 100 213 0 ENST00000307729.7:c.1385C>T p.Thr462Ile p.T462I ENST00000307729 462 aCt/aTt 0 +MMACHC UCSF GRCh37 1 45973070 45973070 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 29 46 1 ENST00000401061.4:c.124C>T p.Pro42Ser p.P42S ENST00000401061 NM_015506.2 42 Ccg/Tcg 0 +MMP16 UCSF GRCh37 8 89058896 89058896 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 286 105 196 0 ENST00000286614.6:c.1489+1G>A p.X497_splice ENST00000286614 NM_005941.4 0 +MMP2 UCSF GRCh37 16 55525787 55525787 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 42 81 0 ENST00000219070.4:c.1255G>A p.Ala419Thr p.A419T ENST00000219070 NM_004530.4 419 Gcc/Acc 0 +MMP26 UCSF GRCh37 11 5010920 5010920 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 48 84 0 ENST00000300762.1:c.142C>T p.Leu48Phe p.L48F ENST00000300762 NM_021801.3 48 Ctc/Ttc 0 +MMRN1 UCSF GRCh37 4 90856881 90856881 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 84 153 0 ENST00000264790.2:c.2050G>A p.Ala684Thr p.A684T ENST00000264790 NM_007351.2 684 Gct/Act 0 +MMS22L UCSF GRCh37 6 97711230 97711230 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 75 157 0 ENST00000275053.4:c.923G>A p.Ser308Asn p.S308N ENST00000275053 NM_198468.2 308 aGt/aAt 0 +MOCOS UCSF GRCh37 18 33778720 33778720 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 37 96 0 ENST00000261326.5:c.299+1G>A p.X100_splice ENST00000261326 NM_017947.2 0 +MOCS1 UCSF GRCh37 6 39877675 39877675 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 58 123 0 ENST00000340692.5:c.1006G>A p.Val336Ile p.V336I ENST00000340692 336 Gta/Ata 0 +MON1A UCSF GRCh37 3 49946495 49946495 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 0 26 73 0 ENST00000296473.3:c.1911C>T p.Ile637= p.I637= ENST00000296473 NM_032355.3 637 atC/atT 0 +MON1B UCSF GRCh37 16 77227388 77227388 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 48 96 0 ENST00000248248.3:c.189G>A p.Pro63= p.P63= ENST00000248248 NM_014940.2 63 ccG/ccA 0 +MPP2 UCSF GRCh37 17 41958890 41958890 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 33 76 0 ENST00000461854.1:c.821G>A p.Gly274Asp p.G274D ENST00000461854 NM_001278372.1 274 gGc/gAc 0 +MPRIP UCSF GRCh37 17 17061919 17061919 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 38 38 0 ENST00000341712.4:c.1649C>T p.Pro550Leu p.P550L ENST00000341712 550 cCc/cTc 0 +MRGPRX1 UCSF GRCh37 11 18955369 18955369 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 78 295 0 ENST00000302797.3:c.963G>A p.Glu321= p.E321= ENST00000302797 NM_147199.3 321 gaG/gaA 0 +MRGPRX2 UCSF GRCh37 11 19077859 19077859 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 110 191 0 ENST00000329773.2:c.91C>T p.Leu31= p.L31= ENST00000329773 NM_054030.2 31 Ctg/Ttg 0 +MRGPRX3 UCSF GRCh37 11 18159399 18159399 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 66 142 0 ENST00000396275.2:c.650C>T p.Thr217Ile p.T217I ENST00000396275 NM_054031.3 217 aCc/aTc 0 +MRPL13 UCSF GRCh37 8 121426229 121426229 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 221 53 140 0 ENST00000306185.3:c.515+1G>A p.X172_splice ENST00000306185 NM_014078.5 0 +MRPL39 UCSF GRCh37 21 26960020 26960020 + intron_variant Intron SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 46 99 0 ENST00000352957.4:c.969+1127G>A *323* ENST00000352957 NM_017446.3 0 +MRPL39 UCSF GRCh37 21 26978967 26978967 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 48 102 0 ENST00000352957.4:c.74G>A p.Arg25Lys p.R25K ENST00000352957 NM_017446.3 25 aGa/aAa 0 +MRPL41 UCSF GRCh37 9 140446606 140446606 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 13 20 0 ENST00000371443.5:c.73C>T p.Arg25Trp p.R25W ENST00000371443 NM_032477.2 25 Cgg/Tgg 0 +MRPL51 UCSF GRCh37 12 6602104 6602104 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 63 142 0 ENST00000229238.3:c.114C>T p.Leu38= p.L38= ENST00000229238 NM_016497.3 38 ctC/ctT 0 +MRPS22 UCSF GRCh37 3 139065749 139065749 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 80 185 0 ENST00000310776.4:c.202C>T p.Pro68Ser p.P68S ENST00000310776 NM_020191.2 68 Cct/Tct 0 +MS4A7 UCSF GRCh37 11 60156911 60156911 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 48 115 0 ENST00000300184.3:c.388G>A p.Ala130Thr p.A130T ENST00000300184 NM_206939.1 130 Gca/Aca 0 +MSI2 UCSF GRCh37 17 55693427 55693427 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 94 154 0 ENST00000284073.2:c.634C>T p.Leu212Phe p.L212F ENST00000284073 NM_138962.2 212 Ctt/Ttt 0 +MTA2 UCSF GRCh37 11 62362016 62362016 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 61 143 0 ENST00000278823.2:c.1664G>A p.Gly555Asp p.G555D ENST00000278823 NM_004739.3 555 gGc/gAc 0 +MTA3 UCSF GRCh37 2 42836678 42836678 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 150 113 213 0 ENST00000405094.1:c.271C>T p.Leu91Phe p.L91F ENST00000405094 91 Ctc/Ttc 0 +MTBP UCSF GRCh37 8 121457794 121457794 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 167 54 109 0 ENST00000305949.1:c.84G>A p.Glu28= p.E28= ENST00000305949 NM_022045.4 28 gaG/gaA 0 +MTERFD1 UCSF GRCh37 8 97263207 97263207 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 301 98 179 0 ENST00000287025.3:c.604G>A p.Asp202Asn p.D202N ENST00000287025 NM_015942.3 202 Gat/Aat 0 +MTERFD3 UCSF GRCh37 12 107371758 107371758 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 99 177 0 ENST00000240050.4:c.735C>T p.Leu245= p.L245= ENST00000240050 NM_001033050.2 245 ctC/ctT 0 +MTFMT UCSF GRCh37 15 65313862 65313862 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 101 197 0 ENST00000220058.4:c.635G>A p.Gly212Asp p.G212D ENST00000220058 NM_139242.3 212 gGt/gAt 0 +MTMR11 UCSF GRCh37 1 149905829 149905829 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 112 127 212 0 ENST00000439741.2:c.690C>T p.Pro230= p.P230= ENST00000439741 NM_001145862.1 230 ccC/ccT 0 +MUC12 UCSF GRCh37 7 100634404 100634404 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 141 112 207 0 ENST00000379442.3:c.989C>T p.Pro330Leu p.P330L ENST00000379442 330 cCa/cTa 0 +MUC12 UCSF GRCh37 7 100636003 100636003 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 305 112 500 0 ENST00000379442.3:c.2588G>A p.Ser863Asn p.S863N ENST00000379442 863 aGc/aAc 0 +MUC16 UCSF GRCh37 19 9065187 9065187 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 113 218 0 ENST00000397910.4:c.22259C>T p.Ala7420Val p.A7420V ENST00000397910 NM_024690.2 7420 gCt/gTt 0 +MUC16 UCSF GRCh37 19 9088766 9088766 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 154 148 234 0 ENST00000397910.4:c.3049C>T p.Pro1017Ser p.P1017S ENST00000397910 NM_024690.2 1017 Cca/Tca 0 +MUC4 UCSF GRCh37 3 195507918 195507918 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 514 109 606 0 ENST00000463781.3:c.10533C>T p.Ser3511= p.S3511= ENST00000463781 NM_018406.6 3511 tcC/tcT 0 +MUC6 UCSF GRCh37 11 1017468 1017468 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 184 90 639 0 ENST00000421673.2:c.5333C>T p.Thr1778Ile p.T1778I ENST00000421673 NM_005961.2 1778 aCc/aTc 0 +MVK UCSF GRCh37 12 110028600 110028600 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 40 95 0 ENST00000228510.3:c.702G>A p.Leu234= p.L234= ENST00000228510 NM_001114185.1 234 ctG/ctA 0 +MYBL1 UCSF GRCh37 8 67478442 67478442 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 65 142 0 ENST00000522677.3:c.1987C>T p.Pro663Ser p.P663S ENST00000522677 NM_001080416.2 663 Cca/Tca 0 +MYBPC2 UCSF GRCh37 19 50940918 50940918 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 65 107 0 ENST00000357701.5:c.515G>A p.Ser172Asn p.S172N ENST00000357701 NM_004533.3 172 aGt/aAt 0 +MYBPH UCSF GRCh37 1 203138040 203138040 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 96 194 0 ENST00000255416.4:c.1411G>A p.Val471Ile p.V471I ENST00000255416 NM_004997.2 471 Gtc/Atc 0 +MYCN UCSF GRCh37 2 16085664 16085664 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 24 46 0 ENST00000281043.3:c.840C>T p.Val280= p.V280= ENST00000281043 NM_005378.4 280 gtC/gtT 0 +MYF6 UCSF GRCh37 12 81101749 81101749 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 56 83 1 ENST00000228641.3:c.251C>T p.Thr84Ile p.T84I ENST00000228641 NM_002469.2 84 aCc/aTc 0 +MYH1 UCSF GRCh37 17 10411716 10411716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 77 182 0 ENST00000226207.5:c.1861G>A p.Ala621Thr p.A621T ENST00000226207 NM_005963.3 621 Gct/Act 0 +MYH1 UCSF GRCh37 17 10406468 10406468 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 54 218 1 ENST00000226207.5:c.2789C>A p.Ala930Asp p.A930D ENST00000226207 NM_005963.3 930 gCt/gAt 0 +MYH1 UCSF GRCh37 17 10411855 10411855 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 117 202 0 ENST00000226207.5:c.1722C>T p.Gly574= p.G574= ENST00000226207 NM_005963.3 574 ggC/ggT 0 +MYH14 UCSF GRCh37 19 50764778 50764778 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 13 55 0 ENST00000376970.2:c.2447G>A p.Ser816Asn p.S816N ENST00000376970 NM_024729.3 816 aGc/aAc 0 +MYH3 UCSF GRCh37 17 10532992 10532992 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 55 157 0 ENST00000583535.1:c.5718G>A p.Glu1906= p.E1906= ENST00000583535 NM_002470.3 1906 gaG/gaA 0 +MYH3 UCSF GRCh37 17 10555770 10555770 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 66 157 0 ENST00000583535.1:c.315C>T p.Asn105= p.N105= ENST00000583535 NM_002470.3 105 aaC/aaT 0 +MYH4 UCSF GRCh37 17 10369707 10369707 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 114 194 0 ENST00000255381.2:c.231C>T p.Val77= p.V77= ENST00000255381 NM_017533.2 77 gtC/gtT 0 +MYH8 UCSF GRCh37 17 10322311 10322311 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 132 75 166 0 ENST00000403437.2:c.247A>G p.Asn83Asp p.N83D ENST00000403437 NM_002472.2 83 Aac/Gac 0 +MYH8 UCSF GRCh37 17 10310022 10310022 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 66 161 0 ENST00000403437.2:c.2156G>A p.Gly719Asp p.G719D ENST00000403437 NM_002472.2 719 gGt/gAt 0 +MYLK3 UCSF GRCh37 16 46766561 46766561 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 18 13 0 ENST00000394809.4:c.1021G>A p.Glu341Lys p.E341K ENST00000394809 NM_182493.2 341 Gag/Aag 0 +MYNN UCSF GRCh37 3 169496819 169496819 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 81 127 0 ENST00000349841.5:c.530C>T p.Ser177Phe p.S177F ENST00000349841 NM_018657.4 177 tCt/tTt 0 +MYO10 UCSF GRCh37 5 16761595 16761595 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 59 127 0 ENST00000513610.1:c.1717C>T p.Leu573Phe p.L573F ENST00000513610 NM_012334.2 573 Ctc/Ttc 0 +MYO15A UCSF GRCh37 17 18077205 18077205 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 28 43 0 ENST00000205890.5:c.10461C>T p.Ala3487= p.A3487= ENST00000205890 NM_016239.3 3487 gcC/gcT 0 +MYO18B UCSF GRCh37 22 26422559 26422559 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 141 219 0 ENST00000536101.1:c.6619G>A p.Asp2207Asn p.D2207N ENST00000536101 2207 Gac/Aac 0 +MYO1D UCSF GRCh37 17 31082612 31082612 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 58 130 0 ENST00000318217.5:c.1365C>T p.Ile455= p.I455= ENST00000318217 NM_015194.1 455 atC/atT 0 +MYO1G UCSF GRCh37 7 45010558 45010558 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 14 47 0 ENST00000258787.7:c.947C>T p.Ala316Val p.A316V ENST00000258787 NM_033054.2 316 gCc/gTc 0 +MYO1H UCSF GRCh37 12 109847811 109847811 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 42 91 0 ENST00000310903.5:c.1219C>T p.Gln407Ter p.Q407* ENST00000310903 407 Caa/Taa 0 +MYO5A UCSF GRCh37 15 52611418 52611418 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 73 156 1 ENST00000399231.3:c.4998G>A p.Arg1666= p.R1666= ENST00000399231 NM_000259.3 1666 cgG/cgA 0 +MYO7A UCSF GRCh37 11 76917230 76917230 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 20 66 0 ENST00000409709.3:c.5725C>T p.Pro1909Ser p.P1909S ENST00000409709 NM_000260.3 1909 Cct/Tct 0 +MYO7A UCSF GRCh37 11 76853811 76853811 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 27 55 0 ENST00000409709.3:c.75G>A p.Gly25= p.G25= ENST00000409709 NM_000260.3 25 ggG/ggA 0 +MYO9A UCSF GRCh37 15 72170512 72170512 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 58 142 0 ENST00000356056.5:c.5800G>A p.Glu1934Lys p.E1934K ENST00000356056 NM_006901.3 1934 Gaa/Aaa 0 +MYO9A UCSF GRCh37 15 72122464 72122464 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 94 187 0 ENST00000356056.5:c.7026C>T p.Asn2342= p.N2342= ENST00000356056 NM_006901.3 2342 aaC/aaT 0 +MYOG UCSF GRCh37 1 203054982 203054982 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 49 82 0 ENST00000241651.4:c.108G>A p.Glu36= p.E36= ENST00000241651 NM_002479.5 36 gaG/gaA 0 +MYOM2 UCSF GRCh37 8 2017412 2017412 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 49 101 0 ENST00000262113.4:c.669C>T p.Asp223= p.D223= ENST00000262113 NM_003970.2 223 gaC/gaT 0 +MYOM3 UCSF GRCh37 1 24406551 24406551 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 46 104 0 ENST00000374434.3:c.2541G>A p.Gln847= p.Q847= ENST00000374434 NM_152372.3 847 caG/caA 0 +N4BP1 UCSF GRCh37 16 48596018 48596018 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 117 220 1 ENST00000262384.3:c.536C>T p.Pro179Leu p.P179L ENST00000262384 NM_153029.3 179 cCc/cTc 0 +N4BP2 UCSF GRCh37 4 40121568 40121568 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 57 128 0 ENST00000261435.6:c.1837G>A p.Asp613Asn p.D613N ENST00000261435 NM_018177.4 613 Gat/Aat 0 +NAA16 UCSF GRCh37 13 41894916 41894916 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 67 139 0 ENST00000379406.3:c.358C>T p.Leu120Phe p.L120F ENST00000379406 NM_024561.4 120 Ctc/Ttc 0 +NAA16 UCSF GRCh37 13 41893038 41893038 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 51 91 0 ENST00000379406.3:c.236G>A p.Ser79Asn p.S79N ENST00000379406 NM_024561.4 79 aGt/aAt 0 +NACA UCSF GRCh37 12 57114999 57114999 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 39 75 0 ENST00000356769.3:c.70+3237C>T *24* ENST00000356769 NM_001113202.1 0 +NACAD UCSF GRCh37 7 45122972 45122972 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 22 76 0 ENST00000490531.2:c.2807G>A p.Gly936Asp p.G936D ENST00000490531 NM_001146334.1 936 gGt/gAt 0 +NACC1 UCSF GRCh37 19 13246135 13246135 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 32 57 0 ENST00000292431.4:c.114C>T p.Gly38= p.G38= ENST00000292431 NM_052876.3 38 ggC/ggT 0 +NAPG UCSF GRCh37 18 10533534 10533534 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 17 62 0 ENST00000322897.6:c.211C>T p.Leu71Phe p.L71F ENST00000322897 NM_003826.2 71 Ctt/Ttt 0 +NAPRT1 UCSF GRCh37 8 144660099 144660099 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 19 43 0 ENST00000449291.2:c.241G>A p.Ala81Thr p.A81T ENST00000449291 81 Gcc/Acc 0 +NAPRT1 UCSF GRCh37 8 144657681 144657681 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 26 68 0 ENST00000449291.2:c.1203G>A p.Gly401= p.G401= ENST00000449291 401 ggG/ggA 0 +NARS2 UCSF GRCh37 11 78282414 78282414 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 42 103 0 ENST00000281038.5:c.217C>T p.Leu73Phe p.L73F ENST00000281038 NM_001243251.1 73 Ctt/Ttt 0 +NBAS UCSF GRCh37 2 15629017 15629017 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 103 214 0 ENST00000281513.5:c.1083+1G>A p.X361_splice ENST00000281513 NM_015909.3 0 +NBAS UCSF GRCh37 2 15601325 15601325 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 62 143 0 ENST00000281513.5:c.2339G>A p.Cys780Tyr p.C780Y ENST00000281513 NM_015909.3 780 tGt/tAt 0 +NBEA UCSF GRCh37 13 36180590 36180590 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 73 178 0 ENST00000400445.3:c.7324C>T p.Pro2442Ser p.P2442S ENST00000400445 NM_015678.4 2442 Cca/Tca 0 +NBEA UCSF GRCh37 13 35747630 35747630 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 70 158 0 ENST00000400445.3:c.4453G>A p.Glu1485Lys p.E1485K ENST00000400445 NM_015678.4 1485 Gaa/Aaa 0 +NBEAL2 UCSF GRCh37 3 47041495 47041495 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 61 89 0 ENST00000450053.3:c.3906C>T p.Pro1302= p.P1302= ENST00000450053 NM_015175.2 1302 ccC/ccT 0 +NBPF1 UCSF GRCh37 1 16902964 16902964 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 546 63 861 0 ENST00000430580.2:c.1917C>T p.Val639= p.V639= ENST00000430580 NM_017940.4 639 gtC/gtT 0 +NCAN UCSF GRCh37 19 19330107 19330107 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 14 17 0 ENST00000252575.6:c.457G>A p.Val153Met p.V153M ENST00000252575 NM_004386.2 153 Gtg/Atg 0 +NCAN UCSF GRCh37 19 19339079 19339079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 75 127 0 ENST00000252575.6:c.2650G>A p.Val884Ile p.V884I ENST00000252575 NM_004386.2 884 Gtt/Att 0 +NCAPD2 UCSF GRCh37 12 6626819 6626819 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 49 44 121 0 ENST00000315579.5:c.1378A>G p.Met460Val p.M460V ENST00000315579 NM_014865.3 460 Atg/Gtg 0 +NCAPD2 UCSF GRCh37 12 6626830 6626830 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 38 110 0 ENST00000315579.5:c.1389G>A p.Gln463= p.Q463= ENST00000315579 NM_014865.3 463 caG/caA 0 +NCAPD2 UCSF GRCh37 12 6634766 6634766 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 56 109 0 ENST00000315579.5:c.2232G>A p.Gln744= p.Q744= ENST00000315579 NM_014865.3 744 caG/caA 0 +NCAPG2 UCSF GRCh37 7 158445019 158445019 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 156 110 194 0 ENST00000356309.3:c.2900G>A p.Arg967Gln p.R967Q ENST00000356309 NM_017760.5 967 cGg/cAg 0 +NCF2 UCSF GRCh37 1 183559494 183559494 + 5_prime_UTR_variant 5'UTR SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 48 72 0 ENST00000367535.3:c.-30C>T *10* ENST00000367535 NM_000433.3 0 +NCF2 UCSF GRCh37 1 183532372 183532372 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 53 132 0 ENST00000367535.3:c.1248G>A p.Gln416= p.Q416= ENST00000367535 NM_000433.3 416 caG/caA 0 +NCKAP1L UCSF GRCh37 12 54929930 54929930 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 56 154 0 ENST00000293373.6:c.2974G>A p.Glu992Lys p.E992K ENST00000293373 NM_005337.4 992 Gag/Aag 0 +NCLN UCSF GRCh37 19 3207468 3207468 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 51 70 0 ENST00000246117.4:c.1632+1G>A p.X544_splice ENST00000246117 NM_020170.3 0 +NCOR1 UCSF GRCh37 17 16042446 16042446 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 18 79 0 ENST00000268712.3:c.1228G>A p.Ala410Thr p.A410T ENST00000268712 NM_006311.3 410 Gca/Aca 0 +NDUFA5 UCSF GRCh37 7 123190599 123190599 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 98 159 0 ENST00000355749.2:c.108G>A p.Glu36= p.E36= ENST00000355749 NM_005000.2 36 gaG/gaA 0 +NDUFA8 UCSF GRCh37 9 124906657 124906657 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 121 45 120 0 ENST00000373768.3:c.382G>A p.Val128Ile p.V128I ENST00000373768 NM_014222.2 128 Gtc/Atc 0 +NDUFB1 UCSF GRCh37 14 92583900 92583900 + missense_variant Missense_Mutation SNP C C G NOVEL P10_Rec Untested WXS Illumina HiSeq 50 45 110 0 ENST00000553514.1:c.82G>C p.Asp28His p.D28H ENST00000553514 28 Gac/Cac 0 +NDUFB8 UCSF GRCh37 10 102286283 102286283 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 53 100 0 ENST00000299166.4:c.341G>A p.Arg114Lys p.R114K ENST00000299166 NM_005004.2 114 aGg/aAg 0 +NDUFB9 UCSF GRCh37 8 125551466 125551466 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 178 58 112 0 ENST00000276689.3:c.39G>A p.Gln13= p.Q13= ENST00000276689 NM_001278646.1 13 caG/caA 0 +NEB UCSF GRCh37 2 152550904 152550904 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0011 P10_Rec Untested WXS Illumina HiSeq 156 139 243 0 ENST00000172853.10:c.1829G>A p.Gly610Glu p.G610E ENST00000172853 610 gGa/gAa 0 +NEB UCSF GRCh37 2 152490274 152490274 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 134 131 220 0 ENST00000172853.10:c.8890-2941C>T *2964* ENST00000172853 0 +NEGR1 UCSF GRCh37 1 72400806 72400806 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 46 97 0 ENST00000357731.5:c.365C>T p.Thr122Ile p.T122I ENST00000357731 NM_173808.2 122 aCt/aTt 0 +NEIL1 UCSF GRCh37 15 75641296 75641296 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 30 53 0 ENST00000355059.4:c.50C>T p.Ala17Val p.A17V ENST00000355059 NM_024608.3 17 gCc/gTc 0 +NEK6 UCSF GRCh37 9 127101923 127101923 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 85 103 0 ENST00000320246.5:c.696C>T p.Ser232= p.S232= ENST00000320246 NM_014397.5 232 tcC/tcT 0 +NES UCSF GRCh37 1 156640343 156640343 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 76 144 0 ENST00000368223.3:c.3637G>A p.Asp1213Asn p.D1213N ENST00000368223 NM_006617.1 1213 Gat/Aat 0 +NES UCSF GRCh37 1 156642923 156642923 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 32 71 0 ENST00000368223.3:c.1057C>T p.Pro353Ser p.P353S ENST00000368223 NM_006617.1 353 Cca/Tca 0 +NET1 UCSF GRCh37 10 5488735 5488735 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 50 96 0 ENST00000355029.4:c.256-5058G>A *86* ENST00000355029 NM_001047160.2 0 +NEURL4 UCSF GRCh37 17 7227496 7227496 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 48 99 0 ENST00000399464.2:c.1993C>T p.Pro665Ser p.P665S ENST00000399464 NM_032442.2 665 Ccc/Tcc 0 +NFAT5 UCSF GRCh37 16 69727984 69727984 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 60 140 0 ENST00000354436.2:c.4202C>T p.Pro1401Leu p.P1401L ENST00000354436 NM_006599.3 1401 cCt/cTt 0 +NFATC2 UCSF GRCh37 20 50049043 50049043 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 24 30 0 ENST00000396009.3:c.2283C>T p.Ser761= p.S761= ENST00000396009 NM_001258297.1 761 agC/agT 0 +NFKB1 UCSF GRCh37 4 103528456 103528456 + missense_variant Missense_Mutation SNP G G A snp132_rs111293796 P10_Rec Untested WXS Illumina HiSeq 71 69 113 0 ENST00000394820.4:c.2101G>A p.Ala701Thr p.A701T ENST00000394820 701 Gca/Aca 0 +NFKB2 UCSF GRCh37 10 104156010 104156010 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 41 80 0 ENST00000369966.3:c.22G>A p.Gly8Ser p.G8S ENST00000369966 NM_001077494.2 8 Ggt/Agt 0 +NFRKB UCSF GRCh37 11 129755479 129755479 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 43 70 0 ENST00000446488.3:c.491G>A p.Ser164Asn p.S164N ENST00000446488 NM_001143835.1 164 aGt/aAt 0 +NFYA UCSF GRCh37 6 41048556 41048556 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 44 108 0 ENST00000341376.6:c.82G>A p.Gly28Ser p.G28S ENST00000341376 NM_002505.4 28 Ggt/Agt 0 +NGFR UCSF GRCh37 17 47590187 47590187 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 42 87 0 ENST00000172229.3:c.1100G>A p.Gly367Asp p.G367D ENST00000172229 NM_002507.3 367 gGc/gAc 0 +NID2 UCSF GRCh37 14 52496330 52496330 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 59 121 0 ENST00000216286.5:c.2336G>A p.Gly779Glu p.G779E ENST00000216286 NM_007361.3 779 gGg/gAg 0 +NINJ2 UCSF GRCh37 12 772650 772650 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 66 130 0 ENST00000305108.4:c.15C>T p.Ser5= p.S5= ENST00000305108 NM_016533.4 5 tcC/tcT 0 +NKAPL UCSF GRCh37 6 28227951 28227951 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 36 96 0 ENST00000343684.3:c.802C>T p.Gln268Ter p.Q268* ENST00000343684 NM_001007531.2 268 Cag/Tag 0 +NLGN4X UCSF GRCh37 X 5947330 5947330 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 89 177 0 ENST00000275857.6:c.616G>A p.Gly206Arg p.G206R ENST00000275857 NM_020742.2 206 Gga/Aga 0 +NLGN4X UCSF GRCh37 X 5821576 5821576 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 55 150 0 ENST00000275857.6:c.1143C>T p.Asp381= p.D381= ENST00000275857 NM_020742.2 381 gaC/gaT 0 +NLRP4 UCSF GRCh37 19 56390315 56390315 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 27 60 0 ENST00000301295.6:c.2852C>T p.Ala951Val p.A951V ENST00000301295 NM_134444.4 951 gCc/gTc 0 +NLRP4 UCSF GRCh37 19 56370596 56370596 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 49 179 0 ENST00000301295.6:c.1837G>A p.Glu613Lys p.E613K ENST00000301295 NM_134444.4 613 Gag/Aag 0 +NLRX1 UCSF GRCh37 11 119054035 119054035 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 52 111 0 ENST00000292199.2:c.2815G>A p.Asp939Asn p.D939N ENST00000292199 NM_024618.2 939 Gat/Aat 0 +NLRX1 UCSF GRCh37 11 119052980 119052980 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 58 88 0 ENST00000292199.2:c.2532C>T p.Tyr844= p.Y844= ENST00000292199 NM_024618.2 844 taC/taT 0 +NME4 UCSF GRCh37 16 450246 450246 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 46 127 0 ENST00000219479.2:c.468G>A p.Val156= p.V156= ENST00000219479 NM_005009.2 156 gtG/gtA 0 +NOC2L UCSF GRCh37 1 894347 894347 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 44 60 0 ENST00000327044.6:c.141C>T p.Ala47= p.A47= ENST00000327044 NM_015658.3 47 gcC/gcT 0 +NOD2 UCSF GRCh37 16 50745116 50745116 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 69 96 0 ENST00000300589.2:c.1294G>A p.Ala432Thr p.A432T ENST00000300589 NM_022162.1 432 Gcg/Acg 0 +NOL8 UCSF GRCh37 9 95083950 95083950 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 13 41 0 ENST00000442668.2:c.281G>A p.Arg94Lys p.R94K ENST00000442668 NM_017948.5 94 aGa/aAa 0 +NONO UCSF GRCh37 X 70510605 70510605 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 53 110 0 ENST00000276079.8:c.118C>T p.Pro40Ser p.P40S ENST00000276079 NM_007363.4 40 Cca/Tca 0 +NONO UCSF GRCh37 X 70518341 70518341 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 110 196 0 ENST00000276079.8:c.1154G>A p.Gly385Asp p.G385D ENST00000276079 NM_007363.4 385 gGt/gAt 0 +NOP2 UCSF GRCh37 12 6677046 6677046 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 62 102 0 ENST00000322166.5:c.39G>A p.Gly13= p.G13= ENST00000322166 NM_001258308.1 13 ggG/ggA 0 +NOTCH1 UCSF GRCh37 9 139395012 139395012 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 47 76 0 ENST00000277541.6:c.5926G>A p.Val1976Ile p.V1976I ENST00000277541 NM_017617.3 1976 Gtc/Atc 0 +NOTCH2 UCSF GRCh37 1 120466339 120466339 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 51 137 0 ENST00000256646.2:c.4780G>A p.Gly1594Ser p.G1594S ENST00000256646 NM_024408.3 1594 Ggt/Agt 0 +NOTCH4 UCSF GRCh37 6 32168734 32168734 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 38 65 0 ENST00000375023.3:c.4189C>T p.Pro1397Ser p.P1397S ENST00000375023 NM_004557.3 1397 Ccg/Tcg 0 +NOTCH4 UCSF GRCh37 6 32187934 32187934 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 45 66 0 ENST00000375023.3:c.1287C>T p.Cys429= p.C429= ENST00000375023 NM_004557.3 429 tgC/tgT 0 +NPAS1 UCSF GRCh37 19 47535576 47535576 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 30 72 0 ENST00000449844.2:c.399C>T p.Val133= p.V133= ENST00000449844 NM_002517.2 133 gtC/gtT 0 +NPAS2 UCSF GRCh37 2 101606778 101606778 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 59 101 0 ENST00000335681.5:c.1888C>T p.Leu630= p.L630= ENST00000335681 NM_002518.3 630 Cta/Tta 0 +NPC2 UCSF GRCh37 14 74953067 74953067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 16 14 33 0 ENST00000555619.1:c.155G>A p.Gly52Glu p.G52E ENST00000555619 NM_006432.3 52 gGa/gAa 0 +NPEPL1 UCSF GRCh37 20 57288599 57288599 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 29 59 0 ENST00000356091.6:c.1125G>A p.Gln375= p.Q375= ENST00000356091 NM_024663.3 375 caG/caA 0 +NPHP3 UCSF GRCh37 3 132419247 132419247 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 80 202 0 ENST00000337331.5:c.1674C>T p.Ser558= p.S558= ENST00000337331 NM_153240.4 558 tcC/tcT 0 +NPHS2 UCSF GRCh37 1 179521766 179521766 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 28 61 0 ENST00000367615.4:c.845C>T p.Ala282Val p.A282V ENST00000367615 NM_014625.2 282 gCt/gTt 0 +NPM3 UCSF GRCh37 10 103541607 103541607 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 81 172 0 ENST00000370110.5:c.423G>A p.Thr141= p.T141= ENST00000370110 NM_006993.2 141 acG/acA 0 +NPR2 UCSF GRCh37 9 35806481 35806481 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 65 131 0 ENST00000342694.2:c.2465C>T p.Ala822Val p.A822V ENST00000342694 NM_003995.3 822 gCc/gTc 0 +NQO2 UCSF GRCh37 6 3019826 3019826 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 60 110 0 ENST00000338130.2:c.633G>A p.Arg211= p.R211= ENST00000338130 211 agG/agA 0 +NR1H2 UCSF GRCh37 19 50880868 50880868 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 41 99 0 ENST00000253727.5:c.6C>T p.Ser2= p.S2= ENST00000253727 NM_007121.5 2 tcC/tcT 0 +NR1I2 UCSF GRCh37 3 119529028 119529028 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 12 34 0 ENST00000393716.2:c.318C>T p.Gly106= p.G106= ENST00000393716 NM_003889.3 106 ggC/ggT 0 +NR1I3 UCSF GRCh37 1 161199705 161199705 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 48 114 0 ENST00000367982.4:c.941C>T p.Ala314Val p.A314V ENST00000367982 314 gCg/gTg 0 +NRIP1 UCSF GRCh37 21 16338166 16338166 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 82 169 0 ENST00000318948.4:c.2348G>A p.Gly783Asp p.G783D ENST00000318948 NM_003489.3 783 gGt/gAt 0 +NRK UCSF GRCh37 X 105139427 105139427 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 114 138 0 ENST00000243300.9:c.491G>A p.Gly164Asp p.G164D ENST00000243300 NM_198465.2 164 gGc/gAc 0 +NRXN1 UCSF GRCh37 2 50149265 50149265 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 62 132 0 ENST00000406316.2:c.4251C>T p.Ile1417= p.I1417= ENST00000406316 NM_004801.4 1417 atC/atT 0 +NRXN2 UCSF GRCh37 11 64418013 64418013 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 75 140 0 ENST00000265459.6:c.3016G>A p.Val1006Met p.V1006M ENST00000265459 NM_015080.3 1006 Gtg/Atg 0 +NSD1 UCSF GRCh37 5 176562676 176562676 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 98 222 0 ENST00000439151.2:c.572C>T p.Ala191Val p.A191V ENST00000439151 NM_022455.4 191 gCc/gTc 0 +NSD1 UCSF GRCh37 5 176562370 176562370 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 76 168 0 ENST00000439151.2:c.266G>A p.Gly89Glu p.G89E ENST00000439151 NM_022455.4 89 gGg/gAg 0 +NSF UCSF GRCh37 17 44788375 44788375 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 59 166 0 ENST00000398238.4:c.1517G>A p.Gly506Asp p.G506D ENST00000398238 NM_006178.3 506 gGt/gAt 0 +NSUN7 UCSF GRCh37 4 40778101 40778101 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 43 161 0 ENST00000381782.2:c.861G>A p.Lys287= p.K287= ENST00000381782 NM_024677.4 287 aaG/aaA 0 +NT5C2 UCSF GRCh37 10 104934647 104934647 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 88 177 0 ENST00000343289.5:c.69C>T p.Ala23= p.A23= ENST00000343289 NM_012229.4 23 gcC/gcT 0 +NTNG2 UCSF GRCh37 9 135073502 135073502 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 35 90 0 ENST00000393229.3:c.363C>T p.Ala121= p.A121= ENST00000393229 NM_032536.2 121 gcC/gcT 0 +NTRK2 UCSF GRCh37 9 87482194 87482194 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 167 89 150 0 ENST00000323115.4:c.1433C>T p.Ala478Val p.A478V ENST00000323115 478 gCc/gTc 0 +NUDT21 UCSF GRCh37 16 56481862 56481862 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 59 122 0 ENST00000300291.5:c.156C>T p.Pro52= p.P52= ENST00000300291 NM_007006.2 52 ccC/ccT 0 +NUMB UCSF GRCh37 14 73749202 73749202 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 39 64 0 ENST00000355058.3:c.961G>A p.Glu321Lys p.E321K ENST00000355058 321 Gaa/Aaa 0 +NUMB UCSF GRCh37 14 73789900 73789900 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 34 88 0 ENST00000355058.3:c.139G>A p.Val47Ile p.V47I ENST00000355058 47 Gta/Ata 0 +NUP107 UCSF GRCh37 12 69125440 69125440 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 48 130 0 ENST00000229179.4:c.1939G>A p.Asp647Asn p.D647N ENST00000229179 NM_020401.2 647 Gat/Aat 0 +NUP107 UCSF GRCh37 12 69125424 69125424 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 44 110 0 ENST00000229179.4:c.1923G>A p.Glu641= p.E641= ENST00000229179 NM_020401.2 641 gaG/gaA 0 +NUP133 UCSF GRCh37 1 229588355 229588355 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 53 131 0 ENST00000261396.3:c.3016G>A p.Glu1006Lys p.E1006K ENST00000261396 NM_018230.2 1006 Gag/Aag 0 +NUP133 UCSF GRCh37 1 229643896 229643896 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 20 43 0 ENST00000261396.3:c.101G>A p.Arg34Lys p.R34K ENST00000261396 NM_018230.2 34 aGg/aAg 0 +NUP153 UCSF GRCh37 6 17661921 17661921 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 79 215 0 ENST00000262077.2:c.1358G>A p.Arg453Lys p.R453K ENST00000262077 NM_001278210.1 453 aGa/aAa 0 +NUP155 UCSF GRCh37 5 37328498 37328498 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 45 121 0 ENST00000231498.3:c.1838C>T p.Pro613Leu p.P613L ENST00000231498 NM_153485.2 613 cCc/cTc 0 +NUP210 UCSF GRCh37 3 13432778 13432778 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 21 55 0 ENST00000254508.5:c.466G>A p.Val156Ile p.V156I ENST00000254508 NM_024923.3 156 Gtc/Atc 0 +NUP88 UCSF GRCh37 17 5290097 5290097 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 120 86 220 0 ENST00000573584.1:c.2093G>A p.Ser698Asn p.S698N ENST00000573584 NM_002532.4 698 aGt/aAt 0 +NXF1 UCSF GRCh37 11 62563641 62563641 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 92 185 0 ENST00000294172.2:c.1358G>A p.Arg453Gln p.R453Q ENST00000294172 NM_006362.4 453 cGg/cAg 0 +NXF3 UCSF GRCh37 X 102334323 102334323 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 142 124 237 1 ENST00000395065.3:c.1299C>T p.Asp433= p.D433= ENST00000395065 NM_022052.1 433 gaC/gaT 0 +NXNL1 UCSF GRCh37 19 17566756 17566756 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 10 21 0 ENST00000301944.2:c.339C>T p.Arg113= p.R113= ENST00000301944 NM_138454.1 113 cgC/cgT 0 +OAS1 UCSF GRCh37 12 113354501 113354501 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 69 175 0 ENST00000202917.5:c.842C>T p.Pro281Leu p.P281L ENST00000202917 NM_016816.2 281 cCc/cTc 0 +OAS1 UCSF GRCh37 12 113354419 113354419 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 65 137 0 ENST00000202917.5:c.760G>A p.Gly254Arg p.G254R ENST00000202917 NM_016816.2 254 Gga/Aga 0 +OBSCN UCSF GRCh37 1 228461576 228461576 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 24 43 0 ENST00000422127.1:c.5243C>T p.Ala1748Val p.A1748V ENST00000422127 NM_001098623.2 1748 gCc/gTc 0 +OBSCN UCSF GRCh37 1 228522236 228522236 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 15 16 0 ENST00000422127.1:c.16078C>T p.Pro5360Ser p.P5360S ENST00000422127 NM_001098623.2 5360 Cct/Tct 0 +OBSCN UCSF GRCh37 1 228552705 228552705 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 9 23 0 ENST00000422127.1:c.18865C>T p.Pro6289Ser p.P6289S ENST00000422127 NM_001098623.2 6289 Ccc/Tcc 0 +OBSCN UCSF GRCh37 1 228557687 228557687 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 33 73 0 ENST00000422127.1:c.20012C>T p.Thr6671Ile p.T6671I ENST00000422127 NM_001098623.2 6671 aCc/aTc 0 +OBSCN UCSF GRCh37 1 228559004 228559004 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 10 25 0 ENST00000422127.1:c.20525C>T p.Ser6842Phe p.S6842F ENST00000422127 NM_001098623.2 6842 tCc/tTc 0 +OBSCN UCSF GRCh37 1 228432260 228432260 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 91 161 0 ENST00000422127.1:c.3469C>T p.Leu1157= p.L1157= ENST00000422127 NM_001098623.2 1157 Ctg/Ttg 0 +OBSL1 UCSF GRCh37 2 220423059 220423059 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 15 28 0 ENST00000404537.1:c.3349G>A p.Asp1117Asn p.D1117N ENST00000404537 NM_015311.2 1117 Gac/Aac 0 +OCRL UCSF GRCh37 X 128691333 128691333 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 50 123 0 ENST00000371113.4:c.270G>A p.Trp90Ter p.W90* ENST00000371113 NM_000276.3 90 tgG/tgA 0 +ODF3L2 UCSF GRCh37 19 463950 463950 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 17 28 0 ENST00000315489.4:c.764C>T p.Ala255Val p.A255V ENST00000315489 NM_182577.2 255 gCt/gTt 0 +ODZ1 UCSF GRCh37 X 123539019 123539019 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 74 141 0 ENST00000371130.3:c.5232C>T p.Ile1744= p.I1744= ENST00000371130 NM_014253.3 1744 atC/atT 0 +ODZ1 UCSF GRCh37 X 123540204 123540204 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 116 116 198 0 ENST00000371130.3:c.5097C>T p.Asn1699= p.N1699= ENST00000371130 NM_014253.3 1699 aaC/aaT 0 +ODZ1 UCSF GRCh37 X 123556420 123556420 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 70 169 0 ENST00000371130.3:c.4152C>T p.Asn1384= p.N1384= ENST00000371130 NM_014253.3 1384 aaC/aaT 0 +ODZ2 UCSF GRCh37 5 167689120 167689120 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 64 128 0 ENST00000518659.1:c.7630G>A p.Val2544Ile p.V2544I ENST00000518659 NM_001122679.1 2544 Gtc/Atc 0 +ODZ3 UCSF GRCh37 4 183664402 183664402 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 100 202 0 ENST00000511685.1:c.3459G>A p.Gly1153= p.G1153= ENST00000511685 1153 ggG/ggA 0 +ODZ4 UCSF GRCh37 11 78433848 78433848 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 71 169 0 ENST00000278550.7:c.3665G>A p.Gly1222Asp p.G1222D ENST00000278550 NM_001098816.2 1222 gGc/gAc 0 +OFD1 UCSF GRCh37 X 13764556 13764556 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 105 209 0 ENST00000340096.6:c.636G>A p.Arg212= p.R212= ENST00000340096 NM_003611.2 212 cgG/cgA 0 +OGDHL UCSF GRCh37 10 50948755 50948755 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 19 46 0 ENST00000374103.4:c.2140+1G>A p.X714_splice ENST00000374103 NM_018245.2 0 +OGT UCSF GRCh37 X 70757678 70757678 + splice_acceptor_variant Splice_Site SNP G G T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 81 167 0 ENST00000373719.3:c.219-1G>T p.X73_splice ENST00000373719 NM_181673.2 0 +OPLAH UCSF GRCh37 8 145109807 145109807 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 25 50 0 ENST00000426825.1:c.2419C>T p.Leu807= p.L807= ENST00000426825 NM_017570.3 807 Ctg/Ttg 0 +OR10G2 UCSF GRCh37 14 22102456 22102456 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 80 169 0 ENST00000542433.1:c.543C>T p.Tyr181= p.Y181= ENST00000542433 NM_001005466.1 181 taC/taT 0 +OR10G9 UCSF GRCh37 11 123894090 123894090 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 62 170 0 ENST00000375024.1:c.371C>T p.Ala124Val p.A124V ENST00000375024 NM_001001953.1 124 gCc/gTc 0 +OR10K1 UCSF GRCh37 1 158435940 158435940 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 133 201 0 ENST00000289451.2:c.589C>T p.Leu197= p.L197= ENST00000289451 NM_001004473.1 197 Ctg/Ttg 0 +OR10K1 UCSF GRCh37 1 158436158 158436158 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 107 209 0 ENST00000289451.2:c.807C>T p.Ser269= p.S269= ENST00000289451 NM_001004473.1 269 agC/agT 0 +OR13C8 UCSF GRCh37 9 107331735 107331735 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 179 107 195 0 ENST00000335040.1:c.287G>A p.Gly96Glu p.G96E ENST00000335040 NM_001004483.1 96 gGg/gAg 0 +OR2G6 UCSF GRCh37 1 248684977 248684977 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 105 87 183 0 ENST00000343414.4:c.30G>A p.Lys10= p.K10= ENST00000343414 NM_001013355.1 10 aaG/aaA 0 +OR2J3 UCSF GRCh37 6 29080164 29080164 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 118 210 0 ENST00000377169.1:c.497C>T p.Thr166Ile p.T166I ENST00000377169 NM_001005216.3 166 aCc/aTc 0 +OR2T27 UCSF GRCh37 1 248814051 248814051 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 11 110 0 ENST00000344889.3:c.135G>A p.Lys45= p.K45= ENST00000344889 NM_001001824.1 45 aaG/aaA 0 +OR4B1 UCSF GRCh37 11 48238562 48238562 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 110 199 0 ENST00000309562.2:c.201G>A p.Val67= p.V67= ENST00000309562 NM_001005470.1 67 gtG/gtA 0 +OR4C3 UCSF GRCh37 11 48347418 48347418 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 18 253 0 ENST00000319856.4:c.926C>T p.Pro309Leu p.P309L ENST00000319856 NM_001004702.1 309 cCa/cTa 0 +OR4K13 UCSF GRCh37 14 20502272 20502272 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 79 161 0 ENST00000315693.2:c.646G>A p.Val216Ile p.V216I ENST00000315693 NM_001004714.1 216 Gtc/Atc 0 +OR4N4 UCSF GRCh37 15 22382483 22382483 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 206 96 236 0 ENST00000328795.4:c.11C>T p.Ala4Val p.A4V ENST00000328795 NM_001005241.2 4 gCa/gTa 0 +OR4Q3 UCSF GRCh37 14 20216283 20216283 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 179 84 202 1 ENST00000331723.1:c.697G>A p.Gly233Ser p.G233S ENST00000331723 NM_172194.1 233 Ggc/Agc 0 +OR51L1 UCSF GRCh37 11 5020514 5020514 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 121 187 0 ENST00000321543.1:c.302C>T p.Ala101Val p.A101V ENST00000321543 NM_001004755.1 101 gCt/gTt 0 +OR52A5 UCSF GRCh37 11 5153120 5153120 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 93 193 0 ENST00000307388.1:c.753C>T p.Phe251= p.F251= ENST00000307388 NM_001005160.2 251 ttC/ttT 0 +OR5AK2 UCSF GRCh37 11 56757227 56757227 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 79 173 0 ENST00000326855.2:c.839C>T p.Thr280Ile p.T280I ENST00000326855 NM_001005323.1 280 aCa/aTa 0 +OR5L2 UCSF GRCh37 11 55595176 55595176 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 138 221 0 ENST00000378397.1:c.482C>T p.Ser161Phe p.S161F ENST00000378397 NM_001004739.1 161 tCc/tTc 0 +OR5P3 UCSF GRCh37 11 7847083 7847083 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 80 174 0 ENST00000328375.1:c.437G>A p.Gly146Asp p.G146D ENST00000328375 NM_153445.1 146 gGc/gAc 0 +OR6S1 UCSF GRCh37 14 21109787 21109787 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 102 195 0 ENST00000320704.3:c.64C>T p.Leu22Phe p.L22F ENST00000320704 NM_001001968.1 22 Ctc/Ttc 0 +OR6T1 UCSF GRCh37 11 123813611 123813611 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 104 216 0 ENST00000321252.2:c.935C>T p.Ala312Val p.A312V ENST00000321252 NM_001005187.1 312 gCt/gTt 0 +OR7C2 UCSF GRCh37 19 15053082 15053082 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 90 186 0 ENST00000248072.3:c.782C>T p.Ser261Phe p.S261F ENST00000248072 NM_012377.1 261 tCt/tTt 0 +OR9K2 UCSF GRCh37 12 55524499 55524499 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 79 168 0 ENST00000305377.5:c.947G>A p.Arg316Lys p.R316K ENST00000305377 NM_001005243.1 316 aGg/aAg 0 +OR9Q1 UCSF GRCh37 11 57947297 57947297 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 60 159 0 ENST00000335397.3:c.381C>T p.Cys127= p.C127= ENST00000335397 NM_001005212.3 127 tgC/tgT 0 +ORC1 UCSF GRCh37 1 52840505 52840505 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 23 87 0 ENST00000371566.1:c.2368C>T p.Leu790= p.L790= ENST00000371566 790 Ctg/Ttg 0 +OSBP UCSF GRCh37 11 59344079 59344079 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 137 130 240 0 ENST00000263847.1:c.2395G>A p.Asp799Asn p.D799N ENST00000263847 NM_002556.2 799 Gac/Aac 0 +OSBPL9 UCSF GRCh37 1 52231629 52231629 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 65 142 0 ENST00000428468.1:c.914G>A p.Gly305Asp p.G305D ENST00000428468 305 gGc/gAc 0 +OTC UCSF GRCh37 X 38271253 38271253 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 89 223 0 ENST00000039007.4:c.1005+1G>A p.X335_splice ENST00000039007 NM_000531.5 0 +OTC UCSF GRCh37 X 38229063 38229063 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 56 134 0 ENST00000039007.4:c.231G>A p.Leu77= p.L77= ENST00000039007 NM_000531.5 77 ttG/ttA 0 +OTOF UCSF GRCh37 2 26690087 26690087 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 78 113 0 ENST00000272371.2:c.4242G>A p.Glu1414= p.E1414= ENST00000272371 NM_194248.2 1414 gaG/gaA 0 +OTOF UCSF GRCh37 2 26696403 26696403 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 31 70 0 ENST00000272371.2:c.3441G>A p.Arg1147= p.R1147= ENST00000272371 NM_194248.2 1147 cgG/cgA 0 +OTOL1 UCSF GRCh37 3 161214879 161214879 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 138 95 243 0 ENST00000327928.4:c.284C>T p.Ala95Val p.A95V ENST00000327928 NM_001080440.1 95 gCt/gTt 0 +OTOP2 UCSF GRCh37 17 72927040 72927040 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 67 96 0 ENST00000331427.4:c.1310C>T p.Thr437Ile p.T437I ENST00000331427 NM_178160.2 437 aCc/aTc 0 +OTUD7B UCSF GRCh37 1 149931686 149931686 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 68 131 0 ENST00000369135.4:c.762G>A p.Trp254Ter p.W254* ENST00000369135 NM_020205.3 254 tgG/tgA 0 +P2RY11 UCSF GRCh37 19 10225389 10225389 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 31 64 0 ENST00000321826.4:c.1100C>T p.Pro367Leu p.P367L ENST00000321826 NM_002566.4 367 cCc/cTc 0 +P2RY2 UCSF GRCh37 11 72945864 72945864 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 34 56 0 ENST00000311131.2:c.660C>T p.Leu220= p.L220= ENST00000311131 NM_176072.2 220 ctC/ctT 0 +P2RY2 UCSF GRCh37 11 72946126 72946126 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 62 98 0 ENST00000311131.2:c.922C>T p.Leu308= p.L308= ENST00000311131 NM_176072.2 308 Ctg/Ttg 0 +PABPC3 UCSF GRCh37 13 25671444 25671444 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 133 87 194 0 ENST00000281589.3:c.1108C>T p.Arg370Cys p.R370C ENST00000281589 NM_030979.2 370 Cgc/Tgc 0 +PABPC4 UCSF GRCh37 1 40038140 40038140 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 76 183 0 ENST00000372857.3:c.312G>A p.Lys104= p.K104= ENST00000372857 NM_003819.3 104 aaG/aaA 0 +PACRGL UCSF GRCh37 4 20706157 20706157 + splice_donor_variant,NMD_transcript_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 39 112 0 ENST00000471979.2:c.52+1G>A p.X18_splice ENST00000471979 0 +PADI3 UCSF GRCh37 1 17592181 17592181 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 46 147 0 ENST00000375460.3:c.374G>A p.Cys125Tyr p.C125Y ENST00000375460 NM_016233.2 125 tGt/tAt 0 +PAF1 UCSF GRCh37 19 39880350 39880350 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 92 146 0 ENST00000221265.3:c.222C>T p.Leu74= p.L74= ENST00000221265 NM_019088.3 74 ctC/ctT 0 +PAK1 UCSF GRCh37 11 77064613 77064613 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 61 160 0 ENST00000356341.3:c.804G>A p.Lys268= p.K268= ENST00000356341 NM_002576.4 268 aaG/aaA 0 +PAK7 UCSF GRCh37 20 9561506 9561506 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 74 172 0 ENST00000353224.5:c.276C>T p.Ile92= p.I92= ENST00000353224 NM_177990.2 92 atC/atT 0 +PALM3 UCSF GRCh37 19 14166215 14166215 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 6 26 0 ENST00000340790.4:c.377C>T p.Ser126Phe p.S126F ENST00000340790 NM_001145028.1 126 tCc/tTc 0 +PAOX UCSF GRCh37 10 135197700 135197700 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 58 117 0 ENST00000278060.5:c.1105G>A p.Val369Ile p.V369I ENST00000278060 NM_152911.2 369 Gtc/Atc 0 +PAPD7 UCSF GRCh37 5 6738823 6738823 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 84 193 0 ENST00000230859.6:c.118G>A p.Gly40Ser p.G40S ENST00000230859 NM_001171805.1 40 Ggt/Agt 0 +PAPLN UCSF GRCh37 14 73726113 73726113 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 33 54 0 ENST00000554301.1:c.1845C>T p.Pro615= p.P615= ENST00000554301 615 ccC/ccT 0 +PAQR6 UCSF GRCh37 1 156215982 156215982 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 28 71 0 ENST00000292291.5:c.111C>T p.Asp37= p.D37= ENST00000292291 NM_198406.2 37 gaC/gaT 0 +PAQR9 UCSF GRCh37 3 142681301 142681301 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 57 89 0 ENST00000340634.3:c.878G>A p.Ser293Asn p.S293N ENST00000340634 NM_198504.2 293 aGc/aAc 0 +PARD3 UCSF GRCh37 10 34408598 34408598 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 18 35 0 ENST00000374789.3:c.3620G>A p.Arg1207Gln p.R1207Q ENST00000374789 NM_019619.3 1207 cGg/cAg 0 +PARD3B UCSF GRCh37 2 206480410 206480410 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 70 168 0 ENST00000406610.2:c.3491C>T p.Pro1164Leu p.P1164L ENST00000406610 NM_205863.3 1164 cCc/cTc 0 +PARP10 UCSF GRCh37 8 145060340 145060340 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 172 45 61 0 ENST00000313028.7:c.64G>A p.Val22Met p.V22M ENST00000313028 NM_032789.3 22 Gtg/Atg 0 +PARP10 UCSF GRCh37 8 145059662 145059662 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 28 52 0 ENST00000313028.7:c.591C>T p.Arg197= p.R197= ENST00000313028 NM_032789.3 197 cgC/cgT 0 +PARP8 UCSF GRCh37 5 50090071 50090071 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 83 57 162 0 ENST00000281631.5:c.768G>A p.Trp256Ter p.W256* ENST00000281631 NM_024615.3 256 tgG/tgA 0 +PARP9 UCSF GRCh37 3 122274837 122274837 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 85 123 0 ENST00000360356.2:c.286G>A p.Val96Ile p.V96I ENST00000360356 NM_001146102.1 96 Gtc/Atc 0 +PARS2 UCSF GRCh37 1 55223689 55223689 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 82 142 0 ENST00000371279.3:c.1146G>A p.Lys382= p.K382= ENST00000371279 NM_152268.3 382 aaG/aaA 0 +PAX8 UCSF GRCh37 2 114002187 114002187 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 67 152 0 ENST00000263334.5:c.206G>A p.Gly69Asp p.G69D ENST00000263334 69 gGc/gAc 0 +PAX8 UCSF GRCh37 2 113984731 113984731 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 11 17 0 ENST00000263334.5:c.1110+1G>A p.X370_splice ENST00000263334 0 +PAXIP1 UCSF GRCh37 7 154767540 154767540 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 84 155 0 ENST00000397192.1:c.940G>A p.Ala314Thr p.A314T ENST00000397192 NM_007349.3 314 Gct/Act 0 +PBK UCSF GRCh37 8 27690588 27690588 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 31 85 0 ENST00000301905.4:c.43G>A p.Glu15Lys p.E15K ENST00000301905 NM_001278945.1 15 Gaa/Aaa 0 +PCDH18 UCSF GRCh37 4 138452772 138452772 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 90 126 0 ENST00000344876.4:c.471C>T p.Pro157= p.P157= ENST00000344876 NM_019035.3 157 ccC/ccT 0 +PCDHA3 UCSF GRCh37 5 140182340 140182340 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 75 113 0 ENST00000522353.2:c.1558C>T p.Leu520= p.L520= ENST00000522353 NM_018906.2 520 Ctg/Ttg 0 +PCDHA3 UCSF GRCh37 5 140181988 140181988 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 83 191 0 ENST00000522353.2:c.1206G>A p.Lys402= p.K402= ENST00000522353 NM_018906.2 402 aaG/aaA 0 +PCDHA5 UCSF GRCh37 5 140201429 140201429 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 62 132 0 ENST00000529859.1:c.69G>A p.Trp23Ter p.W23* ENST00000529859 NM_018908.2 23 tgG/tgA 0 +PCDHA6 UCSF GRCh37 5 140208723 140208723 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 83 204 0 ENST00000529310.1:c.1047G>A p.Glu349= p.E349= ENST00000529310 NM_018909.2 349 gaG/gaA 0 +PCDHA7 UCSF GRCh37 5 140214435 140214435 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 35 174 0 ENST00000525929.1:c.467G>A p.Gly156Asp p.G156D ENST00000525929 NM_018910.2 156 gGc/gAc 0 +PCDHA9 UCSF GRCh37 5 140228547 140228547 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 33 88 0 ENST00000532602.1:c.467G>A p.Gly156Asp p.G156D ENST00000532602 NM_031857.1 156 gGc/gAc 0 +PCDHB5 UCSF GRCh37 5 140517039 140517039 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 56 126 0 ENST00000231134.5:c.2023G>A p.Ala675Thr p.A675T ENST00000231134 NM_015669.2 675 Gcg/Acg 0 +PCDHB9 UCSF GRCh37 5 140567134 140567134 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 56 152 0 ENST00000316105.4:n.242C>T *81* ENST00000316105 0 +PCDHB9 UCSF GRCh37 5 140567721 140567721 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 42 84 0 ENST00000316105.4:n.829G>A *277* ENST00000316105 0 +PCDHGB1 UCSF GRCh37 5 140732149 140732149 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 40 83 0 ENST00000523390.1:c.2322G>A p.Gln774= p.Q774= ENST00000523390 NM_018922.2 774 caG/caA 0 +PCDHGB4 UCSF GRCh37 5 140768177 140768177 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 135 111 214 0 ENST00000519479.1:c.726C>T p.Phe242= p.F242= ENST00000519479 NM_003736.2 242 ttC/ttT 0 +PCDHGB7 UCSF GRCh37 5 140797671 140797671 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 98 77 157 1 ENST00000398594.2:c.245G>A p.Gly82Glu p.G82E ENST00000398594 NM_018927.3 82 gGg/gAg 0 +PCDHGC3 UCSF GRCh37 5 140856768 140856768 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 55 92 0 ENST00000308177.3:c.1085C>T p.Pro362Leu p.P362L ENST00000308177 NM_002588.2 362 cCc/cTc 0 +PCDP1 UCSF GRCh37 2 120413987 120413987 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 31 94 0 ENST00000413369.3:c.2464C>T p.Leu822Phe p.L822F ENST00000413369 NM_001271049.1 822 Ctc/Ttc 0 +PCK1 UCSF GRCh37 20 56140507 56140507 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 73 158 0 ENST00000319441.4:c.1516G>A p.Ala506Thr p.A506T ENST00000319441 NM_002591.3 506 Gcc/Acc 0 +PCNT UCSF GRCh37 21 47783713 47783713 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 55 128 0 ENST00000359568.5:c.2473G>A p.Glu825Lys p.E825K ENST00000359568 NM_006031.5 825 Gaa/Aaa 0 +PCNX UCSF GRCh37 14 71485788 71485788 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 90 200 0 ENST00000304743.2:c.3059G>A p.Gly1020Glu p.G1020E ENST00000304743 NM_014982.2 1020 gGa/gAa 0 +PCYT1B UCSF GRCh37 X 24625961 24625961 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 21 61 0 ENST00000379144.2:c.235G>A p.Val79Ile p.V79I ENST00000379144 NM_004845.4 79 Gta/Ata 0 +PDC UCSF GRCh37 1 186413413 186413413 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 119 246 0 ENST00000391997.2:c.439G>A p.Gly147Ser p.G147S ENST00000391997 NM_002597.4 147 Ggt/Agt 0 +PDCD6 UCSF GRCh37 5 306740 306740 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 76 126 0 ENST00000264933.4:c.232G>A p.Ala78Thr p.A78T ENST00000264933 NM_001267556.1 78 Gcc/Acc 0 +PDE2A UCSF GRCh37 11 72294554 72294554 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 36 97 0 ENST00000334456.5:c.1656C>T p.Leu552= p.L552= ENST00000334456 NM_002599.4 552 ctC/ctT 0 +PDE4A UCSF GRCh37 19 10531444 10531444 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 10 8 0 ENST00000380702.2:c.254+2903G>A *85* ENST00000380702 0 +PDE4DIP UCSF GRCh37 1 144859782 144859782 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 111 24 156 1 ENST00000369354.3:c.6302G>A p.Gly2101Glu p.G2101E ENST00000369354 2101 gGa/gAa 0 +PDE4DIP UCSF GRCh37 1 145075649 145075649 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 64 10 48 0 ENST00000369345.4:c.214G>A p.Ala72Thr p.A72T ENST00000369345 72 Gcg/Acg 0 +PDE4DIP UCSF GRCh37 1 144864250 144864250 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 235 90 343 0 ENST00000369354.3:c.5845G>A p.Glu1949Lys p.E1949K ENST00000369354 1949 Gag/Aag 0 +PDE4DIP UCSF GRCh37 1 144917570 144917570 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 318 111 387 0 ENST00000369354.3:c.1534G>A p.Ala512Thr p.A512T ENST00000369354 512 Gct/Act 0 +PDE4DIP UCSF GRCh37 1 144857006 144857006 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 33 148 0 ENST00000369354.3:c.6479C>T p.Pro2160Leu p.P2160L ENST00000369354 2160 cCt/cTt 0 +PDE6B UCSF GRCh37 4 619530 619530 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 42 87 0 ENST00000496514.1:c.115G>A p.Gly39Arg p.G39R ENST00000496514 39 Ggg/Agg 0 +PDE6B UCSF GRCh37 4 657987 657987 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 30 51 0 ENST00000496514.1:c.2106G>A p.Glu702= p.E702= ENST00000496514 702 gaG/gaA 0 +PDE9A UCSF GRCh37 21 44171225 44171225 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 113 230 0 ENST00000291539.6:c.654-1G>A p.X218_splice ENST00000291539 NM_002606.2 0 +PDGFRB UCSF GRCh37 5 149516589 149516589 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 20 52 0 ENST00000261799.4:c.22C>T p.Pro8Ser p.P8S ENST00000261799 NM_002609.3 8 Cca/Tca 0 +PDIA2 UCSF GRCh37 16 334467 334467 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 8 29 0 ENST00000219406.6:c.280G>A p.Val94Met p.V94M ENST00000219406 NM_006849.2 94 Gtg/Atg 0 +PDIA5 UCSF GRCh37 3 122880194 122880194 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 46 105 0 ENST00000316218.7:c.1371C>T p.Val457= p.V457= ENST00000316218 NM_006810.3 457 gtC/gtT 0 +PDK2 UCSF GRCh37 17 48187335 48187335 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 5 16 0 ENST00000503176.1:c.1098C>T p.Asp366= p.D366= ENST00000503176 NM_002611.4 366 gaC/gaT 0 +PDLIM5 UCSF GRCh37 4 95376501 95376501 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 23 73 0 ENST00000317968.4:c.62G>A p.Gly21Asp p.G21D ENST00000317968 NM_001256428.1 21 gGt/gAt 0 +PDPR UCSF GRCh37 16 70162947 70162947 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 326 114 411 0 ENST00000288050.4:c.529G>A p.Ala177Thr p.A177T ENST00000288050 NM_017990.3 177 Gcc/Acc 0 +PDPR UCSF GRCh37 16 70176293 70176293 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 157 57 220 1 ENST00000288050.4:c.1471+1G>A p.X491_splice ENST00000288050 NM_017990.3 0 +PDS5B UCSF GRCh37 13 33222964 33222964 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 55 150 0 ENST00000315596.10:c.55G>A p.Val19Ile p.V19I ENST00000315596 NM_015032.3 19 Gtc/Atc 0 +PDZD2 UCSF GRCh37 5 32090465 32090465 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 67 162 0 ENST00000438447.1:c.6911C>T p.Thr2304Met p.T2304M ENST00000438447 2304 aCg/aTg 0 +PEAK1 UCSF GRCh37 15 77407640 77407640 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 57 131 0 ENST00000312493.4:c.4099G>A p.Glu1367Lys p.E1367K ENST00000312493 NM_024776.3 1367 Gaa/Aaa 0 +PEAK1 UCSF GRCh37 15 77425714 77425714 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 100 174 0 ENST00000312493.4:c.3710G>A p.Ser1237Asn p.S1237N ENST00000312493 NM_024776.3 1237 aGc/aAc 0 +PECR UCSF GRCh37 2 216946456 216946456 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 29 59 0 ENST00000265322.7:c.9C>T p.Ser3= p.S3= ENST00000265322 NM_018441.5 3 tcC/tcT 0 +PEG3 UCSF GRCh37 19 57327209 57327209 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 81 168 0 ENST00000326441.9:c.2601C>T p.Asp867= p.D867= ENST00000326441 NM_006210.2 867 gaC/gaT 0 +PER2 UCSF GRCh37 2 239165610 239165610 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 43 133 0 ENST00000254657.3:c.2018G>A p.Ser673Asn p.S673N ENST00000254657 NM_022817.2 673 aGc/aAc 0 +PER2 UCSF GRCh37 2 239170986 239170986 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 47 103 0 ENST00000254657.3:c.1154-1G>A p.X385_splice ENST00000254657 NM_022817.2 0 +PEX13 UCSF GRCh37 2 61259071 61259071 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 100 75 163 0 ENST00000295030.5:c.610G>A p.Gly204Ser p.G204S ENST00000295030 NM_002618.3 204 Ggc/Agc 0 +PEX5L UCSF GRCh37 3 179597902 179597902 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 45 98 0 ENST00000467460.1:c.320C>T p.Thr107Ile p.T107I ENST00000467460 NM_001256751.1 107 aCt/aTt 0 +PEX6 UCSF GRCh37 6 42933057 42933057 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 42 90 0 ENST00000304611.8:c.2521G>A p.Asp841Asn p.D841N ENST00000304611 NM_000287.3 841 Gat/Aat 0 +PFKP UCSF GRCh37 10 3147617 3147617 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 46 110 0 ENST00000381125.4:c.698G>A p.Gly233Asp p.G233D ENST00000381125 NM_002627.4 233 gGt/gAt 0 +PFN2 UCSF GRCh37 3 149686298 149686298 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 91 181 0 ENST00000239940.7:c.172G>A p.Gly58Ser p.G58S ENST00000239940 58 Ggt/Agt 0 +PGBD1 UCSF GRCh37 6 28253422 28253422 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 37 48 120 0 ENST00000259883.3:c.491G>A p.Gly164Glu p.G164E ENST00000259883 164 gGg/gAg 0 +PGBD2 UCSF GRCh37 1 249212463 249212463 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 79 153 0 ENST00000329291.5:c.1680G>A p.Arg560= p.R560= ENST00000329291 NM_170725.2 560 agG/agA 0 +PGCP UCSF GRCh37 8 97892204 97892204 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 312 76 203 0 ENST00000220763.5:c.820G>A p.Glu274Lys p.E274K ENST00000220763 NM_016134.3 274 Gag/Aag 0 +PGS1 UCSF GRCh37 17 76399989 76399989 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 73 102 0 ENST00000262764.6:c.1221G>A p.Gln407= p.Q407= ENST00000262764 NM_024419.3 407 caG/caA 0 +PHACTR2 UCSF GRCh37 6 144070135 144070135 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 30 74 0 ENST00000427704.2:c.195G>A p.Lys65= p.K65= ENST00000427704 NM_014721.2 65 aaG/aaA 0 +PHB UCSF GRCh37 17 47482379 47482379 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 8 18 0 ENST00000300408.3:c.794C>T p.Ser265Phe p.S265F ENST00000300408 NM_002634.3 265 tCc/tTc 0 +PHF12 UCSF GRCh37 17 27233388 27233388 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 44 76 0 ENST00000332830.4:c.2828G>A p.Gly943Asp p.G943D ENST00000332830 NM_001033561.1 943 gGc/gAc 0 +PHF23 UCSF GRCh37 17 7139077 7139077 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 110 166 0 ENST00000320316.3:c.1080G>A p.Gly360= p.G360= ENST00000320316 NM_024297.2 360 ggG/ggA 0 +PHKA1 UCSF GRCh37 X 71843054 71843054 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 58 150 0 ENST00000373542.4:c.1865G>A p.Gly622Glu p.G622E ENST00000373542 NM_002637.3 622 gGa/gAa 0 +PHKG1 UCSF GRCh37 7 56151003 56151003 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 39 72 0 ENST00000297373.2:c.515C>T p.Ser172Phe p.S172F ENST00000297373 NM_006213.4 172 tCc/tTc 0 +PHLDB1 UCSF GRCh37 11 118502183 118502183 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 10 29 0 ENST00000361417.2:c.2087G>A p.Ser696Asn p.S696N ENST00000361417 NM_015157.3 696 aGc/aAc 0 +PHLPP1 UCSF GRCh37 18 60527681 60527681 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 183 42 215 0 ENST00000262719.5:c.1913G>A p.Arg638His p.R638H ENST00000262719 638 cGc/cAc 0 +PHTF1 UCSF GRCh37 1 114242401 114242401 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 10 24 0 ENST00000369604.1:c.2067G>A p.Met689Ile p.M689I ENST00000369604 689 atG/atA 0 +PI4KA UCSF GRCh37 22 21096956 21096956 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 55 106 0 ENST00000255882.6:c.3553C>T p.His1185Tyr p.H1185Y ENST00000255882 NM_058004.3 1185 Cat/Tat 0 +PI4KB UCSF GRCh37 1 151278774 151278774 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 49 129 0 ENST00000368873.1:c.1248C>T p.Ala416= p.A416= ENST00000368873 416 gcC/gcT 0 +PIAS4 UCSF GRCh37 19 4028595 4028595 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 20 33 0 ENST00000262971.2:c.669C>T p.Val223= p.V223= ENST00000262971 NM_015897.2 223 gtC/gtT 0 +PIEZO1 UCSF GRCh37 16 88792793 88792793 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 9 17 0 ENST00000301015.9:c.3867C>T p.Ser1289= p.S1289= ENST00000301015 NM_001142864.2 1289 agC/agT 0 +PIEZO2 UCSF GRCh37 18 10672871 10672871 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 50 112 0 ENST00000503781.3:c.7823-1G>A p.X2608_splice ENST00000503781 NM_022068.2 0 +PIGS UCSF GRCh37 17 26898094 26898094 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 43 81 0 ENST00000308360.7:c.147C>T p.Ser49= p.S49= ENST00000308360 NM_033198.3 49 tcC/tcT 0 +PIGT UCSF GRCh37 20 44048995 44048995 + missense_variant Missense_Mutation SNP T T A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 32 44 0 ENST00000279036.6:c.793T>A p.Ser265Thr p.S265T ENST00000279036 NM_015937.5 265 Tcc/Acc 0 +PIK3C3 UCSF GRCh37 18 39613797 39613797 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 57 156 0 ENST00000262039.4:c.1715G>A p.Arg572Lys p.R572K ENST00000262039 NM_002647.2 572 aGa/aAa 0 +PIK3C3 UCSF GRCh37 18 39584421 39584421 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 32 91 0 ENST00000262039.4:c.1086C>T p.Asp362= p.D362= ENST00000262039 NM_002647.2 362 gaC/gaT 0 +PJA2 UCSF GRCh37 5 108714805 108714805 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 80 157 0 ENST00000361189.2:c.383G>A p.Gly128Asp p.G128D ENST00000361189 NM_014819.4 128 gGc/gAc 0 +PKD1 UCSF GRCh37 16 2152522 2152522 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 48 73 0 ENST00000262304.4:c.9061G>A p.Glu3021Lys p.E3021K ENST00000262304 NM_001009944.2 3021 Gag/Aag 0 +PKD1L1 UCSF GRCh37 7 47897327 47897327 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 62 62 106 0 ENST00000289672.2:c.4466T>C p.Val1489Ala p.V1489A ENST00000289672 NM_138295.3 1489 gTg/gCg 0 +PKD1L2 UCSF GRCh37 16 81145904 81145904 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 95 135 1 ENST00000525539.1:c.6847C>T p.Pro2283Ser p.P2283S ENST00000525539 NM_052892.3 2283 Cca/Tca 0 +PKD1L3 UCSF GRCh37 16 71988149 71988149 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 81 178 0 ENST00000534738.1:n.2664G>A *888* ENST00000534738 0 +PKHD1 UCSF GRCh37 6 51735337 51735337 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 50 120 0 ENST00000371117.3:c.7451C>T p.Ala2484Val p.A2484V ENST00000371117 NM_138694.3 2484 gCc/gTc 0 +PKHD1 UCSF GRCh37 6 51920389 51920389 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 34 102 0 ENST00000371117.3:c.1832C>T p.Thr611Ile p.T611I ENST00000371117 NM_138694.3 611 aCa/aTa 0 +PKHD1 UCSF GRCh37 6 51720715 51720715 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 82 225 0 ENST00000371117.3:c.7887C>T p.Asn2629= p.N2629= ENST00000371117 NM_138694.3 2629 aaC/aaT 0 +PKHD1L1 UCSF GRCh37 8 110396319 110396319 + synonymous_variant Silent SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 389 55 213 0 ENST00000378402.5:c.438A>G p.Pro146= p.P146= ENST00000378402 NM_177531.4 146 ccA/ccG 0 +PKN3 UCSF GRCh37 9 131469082 131469082 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 13 27 0 ENST00000291906.4:c.502G>A p.Ala168Thr p.A168T ENST00000291906 NM_013355.3 168 Gcc/Acc 0 +PLAC4 UCSF GRCh37 21 42551485 42551485 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 14 22 0 ENST00000330333.6:c.312+10983G>A *104* ENST00000330333 NM_012105.4 0 +PLCB1 UCSF GRCh37 20 8609010 8609010 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 55 147 0 ENST00000338037.6:c.316G>A p.Val106Met p.V106M ENST00000338037 NM_015192.3 106 Gtg/Atg 0 +PLCB1 UCSF GRCh37 20 8696941 8696941 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 34 95 0 ENST00000338037.6:c.1281C>T p.Tyr427= p.Y427= ENST00000338037 NM_015192.3 427 taC/taT 0 +PLCB2 UCSF GRCh37 15 40594532 40594532 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 36 52 0 ENST00000260402.3:c.391C>T p.Leu131= p.L131= ENST00000260402 NM_004573.2 131 Ctg/Ttg 0 +PLCD4 UCSF GRCh37 2 219487450 219487450 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 132 102 223 0 ENST00000417849.1:c.621G>A p.Glu207= p.E207= ENST00000417849 207 gaG/gaA 0 +PLCE1 UCSF GRCh37 10 96005837 96005837 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 60 109 0 ENST00000260766.3:c.2555C>T p.Ser852Phe p.S852F ENST00000260766 NM_016341.3 852 tCc/tTc 0 +PLCL1 UCSF GRCh37 2 198949169 198949169 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 113 199 0 ENST00000428675.1:c.928C>T p.Leu310Phe p.L310F ENST00000428675 NM_006226.3 310 Ctt/Ttt 0 +PLD3 UCSF GRCh37 19 40883792 40883792 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 33 65 0 ENST00000356508.5:c.1285G>A p.Gly429Arg p.G429R ENST00000356508 NM_001031696.2 429 Gga/Aga 0 +PLEC UCSF GRCh37 8 144991766 144991766 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 257 60 81 0 ENST00000322810.4:c.12634G>A p.Glu4212Lys p.E4212K ENST00000322810 NM_201380.2 4212 Gag/Aag 0 +PLEC UCSF GRCh37 8 144993812 144993812 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 28 40 0 ENST00000322810.4:c.10588G>A p.Ala3530Thr p.A3530T ENST00000322810 NM_201380.2 3530 Gcg/Acg 0 +PLEC UCSF GRCh37 8 144997025 144997025 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 16 18 0 ENST00000322810.4:c.7483G>A p.Ala2495Thr p.A2495T ENST00000322810 NM_201380.2 2495 Gcg/Acg 0 +PLEC UCSF GRCh37 8 145001197 145001197 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 24 29 0 ENST00000322810.4:c.4304C>T p.Ser1435Phe p.S1435F ENST00000322810 NM_201380.2 1435 tCc/tTc 0 +PLEC UCSF GRCh37 8 145006824 145006824 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 25 52 0 ENST00000322810.4:c.2205C>T p.Asp735= p.D735= ENST00000322810 NM_201380.2 735 gaC/gaT 0 +PLEC UCSF GRCh37 8 145010027 145010027 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 21 46 0 ENST00000322810.4:c.1002C>T p.Ile334= p.I334= ENST00000322810 NM_201380.2 334 atC/atT 0 +PLEKHA5 UCSF GRCh37 12 19511364 19511364 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 20 70 0 ENST00000299275.6:c.2843C>T p.Thr948Ile p.T948I ENST00000299275 NM_019012.5 948 aCt/aTt 0 +PLEKHA6 UCSF GRCh37 1 204226627 204226627 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 15 0 ENST00000272203.3:c.1378C>T p.Pro460Ser p.P460S ENST00000272203 NM_014935.4 460 Ccc/Tcc 0 +PLEKHA6 UCSF GRCh37 1 204237376 204237376 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 24 60 0 ENST00000272203.3:c.167C>T p.Pro56Leu p.P56L ENST00000272203 NM_014935.4 56 cCc/cTc 0 +PLEKHG5 UCSF GRCh37 1 6531862 6531862 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 7 30 0 ENST00000400915.3:c.1255C>T p.Leu419= p.L419= ENST00000400915 NM_001042663.1 419 Ctg/Ttg 0 +PLEKHH1 UCSF GRCh37 14 68042659 68042659 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 58 141 0 ENST00000329153.5:c.2289C>T p.Thr763= p.T763= ENST00000329153 NM_020715.2 763 acC/acT 0 +PLEKHH1 UCSF GRCh37 14 68045917 68045917 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 44 60 0 ENST00000329153.5:c.2916G>A p.Glu972= p.E972= ENST00000329153 NM_020715.2 972 gaG/gaA 0 +PLEKHM2 UCSF GRCh37 1 16056318 16056318 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 86 150 0 ENST00000375799.3:c.2102C>T p.Ala701Val p.A701V ENST00000375799 NM_015164.2 701 gCc/gTc 0 +PLEKHO1 UCSF GRCh37 1 150131340 150131340 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 33 74 0 ENST00000369124.4:c.852C>T p.Ala284= p.A284= ENST00000369124 NM_016274.4 284 gcC/gcT 0 +PLIN3 UCSF GRCh37 19 4859655 4859655 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 41 65 1 ENST00000221957.4:c.295G>A p.Gly99Arg p.G99R ENST00000221957 NM_001164194.1 99 Ggg/Agg 0 +PLOD2 UCSF GRCh37 3 145828149 145828149 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 66 165 0 ENST00000360060.3:c.425G>A p.Gly142Glu p.G142E ENST00000360060 NM_000935.2 142 gGa/gAa 0 +PLVAP UCSF GRCh37 19 17476650 17476650 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 44 117 0 ENST00000252590.4:c.624C>T p.His208= p.H208= ENST00000252590 NM_031310.1 208 caC/caT 0 +PLXDC2 UCSF GRCh37 10 20506382 20506382 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 45 133 0 ENST00000377252.4:c.1150G>A p.Glu384Lys p.E384K ENST00000377252 NM_032812.7 384 Gaa/Aaa 0 +PLXNA1 UCSF GRCh37 3 126710278 126710278 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 11 40 0 ENST00000393409.2:c.1246G>A p.Gly416Arg p.G416R ENST00000393409 NM_032242.3 416 Ggg/Agg 0 +PLXNA3 UCSF GRCh37 X 153694768 153694768 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 44 99 0 ENST00000369682.3:c.2849G>A p.Gly950Asp p.G950D ENST00000369682 NM_017514.3 950 gGc/gAc 0 +PLXNB1 UCSF GRCh37 3 48459638 48459638 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 29 54 0 ENST00000296440.6:c.3184G>A p.Ala1062Thr p.A1062T ENST00000296440 NM_001130082.1 1062 Gct/Act 0 +PLXNB3 UCSF GRCh37 X 153039127 153039127 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 21 22 28 0 ENST00000361971.5:c.3238G>A p.Asp1080Asn p.D1080N ENST00000361971 NM_005393.2 1080 Gac/Aac 0 +PLXNB3 UCSF GRCh37 X 153041097 153041097 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 26 54 0 ENST00000361971.5:c.4383C>T p.Cys1461= p.C1461= ENST00000361971 NM_005393.2 1461 tgC/tgT 0 +PLXND1 UCSF GRCh37 3 129279233 129279233 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 23 35 0 ENST00000324093.4:c.5073G>A p.Arg1691= p.R1691= ENST00000324093 NM_015103.2 1691 cgG/cgA 0 +PMF1 UCSF GRCh37 1 156203447 156203447 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 69 199 0 ENST00000368276.4:c.296G>A p.Gly99Glu p.G99E ENST00000368276 NM_001199661.1 99 gGg/gAg 0 +PMFBP1 UCSF GRCh37 16 72166782 72166782 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 84 155 0 ENST00000237353.10:c.1312G>A p.Ala438Thr p.A438T ENST00000237353 NM_031293.2 438 Gcc/Acc 0 +PML UCSF GRCh37 15 74315461 74315461 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 15 15 0 ENST00000268058.3:c.895G>A p.Glu299Lys p.E299K ENST00000268058 NM_033238.2 299 Gag/Aag 0 +PMM1 UCSF GRCh37 22 41973381 41973381 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 1 52 68 0 ENST00000216259.7:c.730C>T p.Gln244Ter p.Q244* ENST00000216259 NM_002676.2 244 Cag/Tag 0 +PMS1 UCSF GRCh37 2 190682849 190682849 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 39 95 0 ENST00000441310.2:c.525C>T p.Leu175= p.L175= ENST00000441310 NM_000534.4 175 ctC/ctT 0 +PNMA2 UCSF GRCh37 8 26366197 26366197 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 91 195 0 ENST00000522362.2:c.75G>A p.Gly25= p.G25= ENST00000522362 NM_007257.5 25 ggG/ggA 0 +PNO1 UCSF GRCh37 2 68385528 68385528 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 90 204 0 ENST00000263657.2:c.224C>T p.Thr75Ile p.T75I ENST00000263657 NM_020143.2 75 aCa/aTa 0 +PNP UCSF GRCh37 14 20943096 20943096 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 59 148 0 ENST00000361505.5:c.450C>T p.Pro150= p.P150= ENST00000361505 NM_000270.3 150 ccC/ccT 0 +PODXL2 UCSF GRCh37 3 127379246 127379246 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 61 161 0 ENST00000342480.6:c.375G>A p.Glu125= p.E125= ENST00000342480 NM_015720.3 125 gaG/gaA 0 +POLA1 UCSF GRCh37 X 24761422 24761422 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 77 170 0 ENST00000379059.3:c.2524G>A p.Gly842Ser p.G842S ENST00000379059 NM_016937.3 842 Ggc/Agc 0 +POLB UCSF GRCh37 8 42213081 42213081 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 60 93 0 ENST00000265421.4:c.418C>T p.Leu140= p.L140= ENST00000265421 NM_002690.2 140 Ctg/Ttg 0 +POLE UCSF GRCh37 12 133244177 133244177 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 124 91 193 0 ENST00000320574.5:c.2231C>T p.Thr744Ile p.T744I ENST00000320574 NM_006231.2 744 aCc/aTc 0 +POLN UCSF GRCh37 4 2083381 2083381 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 33 60 0 ENST00000382865.1:c.2287G>A p.Ala763Thr p.A763T ENST00000382865 NM_181808.2 763 Gca/Aca 0 +POLN UCSF GRCh37 4 2073858 2073858 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 30 112 0 ENST00000382865.1:c.2686C>T p.Pro896Ser p.P896S ENST00000382865 NM_181808.2 896 Cct/Tct 0 +POLN UCSF GRCh37 4 2209757 2209757 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 96 168 0 ENST00000382865.1:c.671C>T p.Thr224Ile p.T224I ENST00000382865 NM_181808.2 224 aCt/aTt 0 +POLQ UCSF GRCh37 3 121151764 121151764 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 79 217 0 ENST00000264233.5:c.7659+1G>A p.X2553_splice ENST00000264233 NM_199420.3 0 +POLR1D UCSF GRCh37 13 28239967 28239967 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 31 150 0 ENST00000399697.3:c.246C>T p.Asn82= p.N82= ENST00000399697 NM_152705.2 82 aaC/aaT 0 +POLR3A UCSF GRCh37 10 79767606 79767606 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 92 182 0 ENST00000372371.3:c.1928G>A p.Ser643Asn p.S643N ENST00000372371 NM_007055.3 643 aGt/aAt 0 +POLR3A UCSF GRCh37 10 79770278 79770278 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 74 104 0 ENST00000372371.3:c.1593C>T p.Thr531= p.T531= ENST00000372371 NM_007055.3 531 acC/acT 0 +POLRMT UCSF GRCh37 19 621684 621684 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 23 29 0 ENST00000588649.2:c.2014C>T p.Arg672Cys p.R672C ENST00000588649 NM_005035.3 672 Cgc/Tgc 0 +POLRMT UCSF GRCh37 19 622877 622877 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 31 0 ENST00000588649.2:c.1399C>T p.Leu467Phe p.L467F ENST00000588649 NM_005035.3 467 Ctt/Ttt 0 +POMT1 UCSF GRCh37 9 134385701 134385701 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 49 76 0 ENST00000372228.3:c.820G>A p.Val274Ile p.V274I ENST00000372228 NM_007171.3 274 Gtc/Atc 0 +POMT2 UCSF GRCh37 14 77786960 77786960 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 10 21 0 ENST00000261534.4:c.65G>A p.Gly22Asp p.G22D ENST00000261534 NM_013382.5 22 gGc/gAc 0 +PON3 UCSF GRCh37 7 95025659 95025659 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 41 90 0 ENST00000265627.5:c.4G>A p.Gly2Arg p.G2R ENST00000265627 NM_000940.2 2 Ggg/Agg 0 +POPDC2 UCSF GRCh37 3 119367215 119367215 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 53 75 0 ENST00000264231.3:c.901C>T p.Pro301Ser p.P301S ENST00000264231 NM_022135.2 301 Ccc/Tcc 0 +POT1 UCSF GRCh37 7 124510964 124510964 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 62 140 0 ENST00000357628.3:c.255+1G>A p.X85_splice ENST00000357628 NM_015450.2 0 +POU2F1 UCSF GRCh37 1 167381512 167381512 + synonymous_variant Silent SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 16 22 22 0 ENST00000541643.3:c.1803C>T p.Ser601= p.S601= ENST00000541643 601 agC/agT 0 +POU5F1B UCSF GRCh37 8 128428899 128428899 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 241 76 146 0 ENST00000465342.2:c.788C>T p.Ala263Val p.A263V ENST00000465342 263 gCc/gTc 0 +PPAPDC1B UCSF GRCh37 8 38125910 38125910 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 47 95 0 ENST00000424479.2:c.253G>A p.Asp85Asn p.D85N ENST00000424479 NM_001102559.1 85 Gac/Aac 0 +PPAPDC3 UCSF GRCh37 9 134165620 134165620 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 43 82 0 ENST00000372264.3:c.236G>A p.Gly79Asp p.G79D ENST00000372264 NM_032728.3 79 gGc/gAc 0 +PPFIA2 UCSF GRCh37 12 81768505 81768505 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 127 120 228 0 ENST00000549396.1:c.1174G>A p.Ala392Thr p.A392T ENST00000549396 NM_003625.3 392 Gct/Act 0 +PPFIA2 UCSF GRCh37 12 81657155 81657155 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 63 177 0 ENST00000549396.1:c.3570C>T p.Asn1190= p.N1190= ENST00000549396 NM_003625.3 1190 aaC/aaT 0 +PPFIBP2 UCSF GRCh37 11 7674408 7674408 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 1 43 94 0 ENST00000299492.4:c.2590C>T p.Pro864Ser p.P864S ENST00000299492 NM_003621.3 864 Cct/Tct 0 +PPIG UCSF GRCh37 2 170487383 170487383 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 64 147 0 ENST00000260970.3:c.647C>T p.Ser216Phe p.S216F ENST00000260970 NM_004792.2 216 tCc/tTc 0 +PPIP5K2 UCSF GRCh37 5 102491695 102491695 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 33 64 0 ENST00000358359.3:c.1486G>A p.Glu496Lys p.E496K ENST00000358359 NM_001281471.1 496 Gag/Aag 0 +PPM1B UCSF GRCh37 2 44428804 44428804 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 89 168 0 ENST00000282412.4:c.466C>T p.Leu156= p.L156= ENST00000282412 NM_002706.4 156 Ctg/Ttg 0 +PPM1D UCSF GRCh37 17 58740364 58740364 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 59 139 0 ENST00000305921.3:c.1269G>A p.Glu423= p.E423= ENST00000305921 NM_003620.3 423 gaG/gaA 0 +PPM1F UCSF GRCh37 22 22277491 22277491 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 58 96 0 ENST00000263212.5:c.1339G>A p.Glu447Lys p.E447K ENST00000263212 NM_014634.3 447 Gag/Aag 0 +PPM1F UCSF GRCh37 22 22277695 22277695 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 28 62 0 ENST00000263212.5:c.1135C>T p.Leu379= p.L379= ENST00000263212 NM_014634.3 379 Ctg/Ttg 0 +PPP1R12A UCSF GRCh37 12 80222115 80222115 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 92 191 0 ENST00000261207.5:c.777G>A p.Glu259= p.E259= ENST00000261207 NM_001143885.1 259 gaG/gaA 0 +PPP1R9A UCSF GRCh37 7 94913617 94913617 + intron_variant Intron SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 87 159 0 ENST00000340694.4:c.2758-1901C>T *920* ENST00000340694 NM_001166163.1 0 +PPP2R1A UCSF GRCh37 19 52719110 52719110 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 55 137 0 ENST00000322088.6:c.886G>A p.Ala296Thr p.A296T ENST00000322088 NM_014225.5 296 Gcc/Acc 0 +PPP2R2D UCSF GRCh37 10 133747977 133747977 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 112 201 0 ENST00000455566.1:c.23C>T p.Thr8Ile p.T8I ENST00000455566 NM_018461.3 8 aCc/aTc 0 +PPP2R5B UCSF GRCh37 11 64698907 64698907 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 30 68 0 ENST00000164133.2:c.892-1G>A p.X298_splice ENST00000164133 NM_006244.3 0 +PPP4R1 UCSF GRCh37 18 9550361 9550361 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 68 178 0 ENST00000400556.3:c.2327G>A p.Arg776Lys p.R776K ENST00000400556 NM_001042388.2 776 aGa/aAa 0 +PPP5C UCSF GRCh37 19 46891687 46891687 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 19 54 0 ENST00000012443.4:c.1158G>A p.Trp386Ter p.W386* ENST00000012443 NM_006247.3 386 tgG/tgA 0 +PPP6C UCSF GRCh37 9 127923179 127923179 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 47 95 0 ENST00000373547.4:c.178G>A p.Asp60Asn p.D60N ENST00000373547 NM_002721.4 60 Gac/Aac 0 +PPPDE1 UCSF GRCh37 1 244852625 244852625 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 54 141 0 ENST00000302550.11:c.190G>A p.Gly64Arg p.G64R ENST00000302550 NM_016076.3 64 Gga/Aga 0 +PPRC1 UCSF GRCh37 10 103901077 103901078 + frameshift_variant Frame_Shift_Ins INS - - C NOVEL P10_Rec Untested WXS Illumina HiSeq 29 0 ENST00000278070.2:c.2819dup p.Pro941ThrfsTer75 p.P941Tfs*75 ENST00000278070 NM_015062.3 938 ccc/cCcc 0 +PPT1 UCSF GRCh37 1 40557012 40557012 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 28 69 0 ENST00000433473.3:c.422G>A p.Gly141Glu p.G141E ENST00000433473 NM_000310.3 141 gGa/gAa 0 +PPT1 UCSF GRCh37 1 40557775 40557775 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 68 139 0 ENST00000433473.3:c.304G>A p.Asp102Asn p.D102N ENST00000433473 NM_000310.3 102 Gat/Aat 0 +PQLC3 UCSF GRCh37 2 11312087 11312087 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 80 162 0 ENST00000295083.3:c.391G>A p.Ala131Thr p.A131T ENST00000295083 NM_152391.3 131 Gca/Aca 0 +PRAM1 UCSF GRCh37 19 8564207 8564207 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 34 65 0 ENST00000423345.4:c.485C>T p.Ala162Val p.A162V ENST00000423345 162 gCg/gTg 0 +PRB2 UCSF GRCh37 12 11546792 11546792 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 66 201 0 ENST00000389362.4:c.220C>T p.Pro74Ser p.P74S ENST00000389362 NM_006248.3 74 Cct/Tct 0 +PRB3 UCSF GRCh37 12 11421042 11421042 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 60 146 0 ENST00000381842.3:c.141C>T p.Pro47= p.P47= ENST00000381842 NM_006249.4 47 ccC/ccT 0 +PRDM10 UCSF GRCh37 11 129787087 129787087 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 41 113 0 ENST00000358825.5:c.2272G>A p.Val758Met p.V758M ENST00000358825 NM_020228.2 758 Gtg/Atg 0 +PRDM13 UCSF GRCh37 6 100061157 100061157 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 14 25 0 ENST00000369215.4:c.646C>T p.Pro216Ser p.P216S ENST00000369215 NM_021620.3 216 Cca/Tca 0 +PRDM15 UCSF GRCh37 21 43259799 43259799 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 85 195 0 ENST00000269844.3:c.1902G>A p.Arg634= p.R634= ENST00000269844 NM_022115.3 634 agG/agA 0 +PRDM2 UCSF GRCh37 1 14108749 14108749 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P10_Rec Untested WXS Illumina HiSeq 7 0 ENST00000235372.7:c.4467delA p.Val1490PhefsTer74 p.V1490Ffs*74 ENST00000235372 NM_012231.4 1487 Aaa/aa 0 +PRDX4 UCSF GRCh37 X 23697334 23697334 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 76 179 0 ENST00000379341.4:c.529C>T p.Leu177Phe p.L177F ENST00000379341 NM_006406.1 177 Ctt/Ttt 0 +PREP UCSF GRCh37 6 105736761 105736761 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 50 129 0 ENST00000369110.3:c.1326C>T p.Tyr442= p.Y442= ENST00000369110 NM_002726.4 442 taC/taT 0 +PREX1 UCSF GRCh37 20 47364366 47364366 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 21 53 0 ENST00000371941.3:c.271C>T p.Leu91Phe p.L91F ENST00000371941 NM_020820.3 91 Ctc/Ttc 0 +PREX1 UCSF GRCh37 20 47273622 47273622 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 14 30 0 ENST00000371941.3:c.2079C>T p.Cys693= p.C693= ENST00000371941 NM_020820.3 693 tgC/tgT 0 +PREX2 UCSF GRCh37 8 69104660 69104660 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 35 61 0 ENST00000288368.4:c.4504G>A p.Ala1502Thr p.A1502T ENST00000288368 NM_024870.2 1502 Gct/Act 0 +PRICKLE4 UCSF GRCh37 6 41752787 41752787 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 52 127 0 ENST00000359201.5:c.355C>T p.Leu119Phe p.L119F ENST00000359201 119 Ctt/Ttt 0 +PRKAR2A UCSF GRCh37 3 48789107 48789107 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 60 85 0 ENST00000265563.8:c.1126G>A p.Asp376Asn p.D376N ENST00000265563 NM_004157.2 376 Gac/Aac 0 +PRKCZ UCSF GRCh37 1 2105397 2105397 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 47 77 0 ENST00000378567.3:c.1347C>T p.Ser449= p.S449= ENST00000378567 NM_002744.4 449 tcC/tcT 0 +PRKD3 UCSF GRCh37 2 37480324 37480324 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 113 79 197 0 ENST00000234179.2:c.2669C>T p.Pro890Leu p.P890L ENST00000234179 NM_005813.3 890 cCt/cTt 0 +PRLHR UCSF GRCh37 10 120354365 120354365 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 28 32 0 ENST00000239032.2:c.392G>A p.Gly131Asp p.G131D ENST00000239032 NM_004248.2 131 gGc/gAc 0 +PRMT10 UCSF GRCh37 4 148575327 148575327 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 99 179 0 ENST00000322396.6:c.1721C>T p.Thr574Ile p.T574I ENST00000322396 NM_138364.2 574 aCt/aTt 0 +PRNP UCSF GRCh37 20 4680067 4680067 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 35 61 0 ENST00000379440.4:c.201G>A p.Gln67= p.Q67= ENST00000379440 NM_001080121.1 67 caG/caA 0 +PRODH2 UCSF GRCh37 19 36297377 36297377 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 46 109 0 ENST00000301175.3:c.1184G>A p.Gly395Glu p.G395E ENST00000301175 NM_021232.1 395 gGg/gAg 0 +PROL1 UCSF GRCh37 4 71275286 71275286 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 125 229 0 ENST00000399575.2:c.241G>A p.Ala81Thr p.A81T ENST00000399575 NM_021225.4 81 Gca/Aca 0 +PROX1 UCSF GRCh37 1 214170076 214170076 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 58 129 0 ENST00000261454.4:c.198G>A p.Lys66= p.K66= ENST00000261454 66 aaG/aaA 0 +PRPF3 UCSF GRCh37 1 150316697 150316697 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 61 129 0 ENST00000324862.6:c.1486G>A p.Val496Ile p.V496I ENST00000324862 NM_004698.2 496 Gta/Ata 0 +PRPF40B UCSF GRCh37 12 50028958 50028958 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 36 89 0 ENST00000380281.1:c.1012G>A p.Glu338Lys p.E338K ENST00000380281 338 Gag/Aag 0 +PRPF8 UCSF GRCh37 17 1554985 1554985 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 85 169 0 ENST00000304992.6:c.6467C>T p.Thr2156Ile p.T2156I ENST00000304992 NM_006445.3 2156 aCc/aTc 0 +PRR15 UCSF GRCh37 7 29606223 29606223 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 21 8 22 0 ENST00000319694.2:c.278G>A p.Arg93His p.R93H ENST00000319694 NM_175887.2 93 cGc/cAc 0 +PRR19 UCSF GRCh37 19 42814728 42814728 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 85 151 0 ENST00000341747.3:c.907G>A p.Val303Ile p.V303I ENST00000341747 NM_199285.2 303 Gtt/Att 0 +PRRC2A UCSF GRCh37 6 31600268 31600268 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 65 103 0 ENST00000376007.4:c.3818G>A p.Gly1273Asp p.G1273D ENST00000376007 NM_080686.2 1273 gGc/gAc 0 +PRRG3 UCSF GRCh37 X 150869246 150869246 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 53 95 0 ENST00000370353.3:c.437C>T p.Ser146Phe p.S146F ENST00000370353 146 tCt/tTt 0 +PRRT2 UCSF GRCh37 16 29825136 29825136 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 46 82 0 ENST00000358758.7:c.761C>T p.Pro254Leu p.P254L ENST00000358758 NM_001256442.1 254 cCt/cTt 0 +PRRT2 UCSF GRCh37 16 29824583 29824583 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 44 97 0 ENST00000358758.7:c.208G>A p.Glu70Lys p.E70K ENST00000358758 NM_001256442.1 70 Gaa/Aaa 0 +PRSS36 UCSF GRCh37 16 31150554 31150554 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 47 65 0 ENST00000268281.4:c.2473G>A p.Gly825Ser p.G825S ENST00000268281 NM_173502.4 825 Ggc/Agc 0 +PRSS36 UCSF GRCh37 16 31159864 31159864 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 16 16 26 0 ENST00000268281.4:c.405G>A p.Glu135= p.E135= ENST00000268281 NM_173502.4 135 gaG/gaA 0 +PRUNE2 UCSF GRCh37 9 79324065 79324065 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 241 137 213 0 ENST00000376718.3:c.3125C>T p.Ser1042Phe p.S1042F ENST00000376718 NM_015225.2 1042 tCt/tTt 0 +PSAT1 UCSF GRCh37 9 80919695 80919695 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 164 56 170 0 ENST00000376588.3:c.236G>A p.Gly79Glu p.G79E ENST00000376588 NM_058179.3 79 gGg/gAg 0 +PSMA3 UCSF GRCh37 14 58718883 58718883 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 63 163 0 ENST00000216455.4:c.151G>A p.Glu51Lys p.E51K ENST00000216455 NM_152132.2 51 Gaa/Aaa 0 +PSMB11 UCSF GRCh37 14 23511517 23511517 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 53 104 1 ENST00000408907.2:c.83C>T p.Ala28Val p.A28V ENST00000408907 NM_001099780.1 28 gCt/gTt 0 +PSMB5 UCSF GRCh37 14 23503905 23503905 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 24 52 0 ENST00000361611.6:c.186C>T p.Thr62= p.T62= ENST00000361611 NM_002797.3 62 acC/acT 0 +PSMB7 UCSF GRCh37 9 127167651 127167651 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 256 109 182 0 ENST00000259457.3:c.456C>T p.His152= p.H152= ENST00000259457 NM_002799.3 152 caC/caT 0 +PSMF1 UCSF GRCh37 20 1145035 1145035 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 99 185 1 ENST00000333082.3:c.679G>A p.Gly227Ser p.G227S ENST00000333082 NM_178578.2 227 Ggc/Agc 0 +PSTPIP1 UCSF GRCh37 15 77321869 77321869 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 9 29 0 ENST00000558012.1:c.517-1G>A p.X173_splice ENST00000558012 NM_003978.3 0 +PTBP2 UCSF GRCh37 1 97250756 97250756 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 68 127 0 ENST00000426398.2:c.850C>T p.Pro284Ser p.P284S ENST00000426398 NM_021190.2 284 Cct/Tct 0 +PTCHD3 UCSF GRCh37 10 27702675 27702675 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 155 63 148 0 ENST00000438700.3:c.505G>A p.Glu169Lys p.E169K ENST00000438700 NM_001034842.3 169 Gag/Aag 0 +PTGER4 UCSF GRCh37 5 40681248 40681248 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 73 113 0 ENST00000302472.3:c.153G>A p.Glu51= p.E51= ENST00000302472 NM_000958.2 51 gaG/gaA 0 +PTGFRN UCSF GRCh37 1 117504007 117504007 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 60 110 0 ENST00000393203.2:c.1356C>T p.Asn452= p.N452= ENST00000393203 NM_020440.2 452 aaC/aaT 0 +PTGR2 UCSF GRCh37 14 74343866 74343866 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 88 159 0 ENST00000267568.4:c.514G>A p.Gly172Arg p.G172R ENST00000267568 NM_152444.2 172 Ggg/Agg 0 +PTGS1 UCSF GRCh37 9 125148858 125148858 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 195 79 200 0 ENST00000362012.2:c.1143C>T p.Asn381= p.N381= ENST00000362012 NM_000962.3 381 aaC/aaT 0 +PTGS1 UCSF GRCh37 9 125145892 125145892 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 37 71 0 ENST00000362012.2:c.867G>A p.Glu289= p.E289= ENST00000362012 NM_000962.3 289 gaG/gaA 0 +PTGS1 UCSF GRCh37 9 125145946 125145946 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 43 85 0 ENST00000362012.2:c.921G>A p.Glu307= p.E307= ENST00000362012 NM_000962.3 307 gaG/gaA 0 +PTH2R UCSF GRCh37 2 209302275 209302275 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 35 90 0 ENST00000272847.2:c.192C>T p.Phe64= p.F64= ENST00000272847 NM_005048.3 64 ttC/ttT 0 +PTK2 UCSF GRCh37 8 141829029 141829043 + inframe_deletion In_Frame_Del DEL GGATCTCAAAGAATT GGATCTCAAAGAATT - NOVEL P10_Rec Untested WXS Illumina HiSeq 199 0 ENST00000521059.1:c.725_739del p.Lys242_Leu247delinsMet p.K242_L247delinsM ENST00000521059 NM_005607.4 242 aAATTCTTTGAGATCCtg/atg 0 +PTK2B UCSF GRCh37 8 27315931 27315931 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 25 34 0 ENST00000346049.5:c.2935G>A p.Ala979Thr p.A979T ENST00000346049 NM_173176.2 979 Gct/Act 0 +PTK2B UCSF GRCh37 8 27296632 27296632 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0045 P10_Rec Untested WXS Illumina HiSeq 51 42 92 1 ENST00000346049.5:c.1728C>T p.Asp576= p.D576= ENST00000346049 NM_173176.2 576 gaC/gaT 0 +PTK6 UCSF GRCh37 20 62161534 62161534 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 44 71 0 ENST00000542869.1:c.762C>T p.Ala254= p.A254= ENST00000542869 NM_001256358.1 254 gcC/gcT 0 +PTPN13 UCSF GRCh37 4 87593580 87593580 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 47 134 0 ENST00000411767.2:c.178C>T p.Pro60Ser p.P60S ENST00000411767 60 Cca/Tca 0 +PTPN4 UCSF GRCh37 2 120702686 120702686 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 46 113 0 ENST00000263708.2:c.1385C>T p.Pro462Leu p.P462L ENST00000263708 NM_002830.3 462 cCt/cTt 0 +PTPN5 UCSF GRCh37 11 18755141 18755141 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 7 104 0 ENST00000358540.2:c.1042G>A p.Asp348Asn p.D348N ENST00000358540 NM_006906.1 348 Gac/Aac 0 +PTPN5 UCSF GRCh37 11 18764003 18764003 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 41 49 0 ENST00000358540.2:c.531C>T p.Pro177= p.P177= ENST00000358540 NM_006906.1 177 ccC/ccT 0 +PTPRA UCSF GRCh37 20 3008476 3008476 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 48 111 0 ENST00000380393.3:c.1909G>A p.Glu637Lys p.E637K ENST00000380393 NM_002836.3 637 Gag/Aag 0 +PTPRB UCSF GRCh37 12 70974815 70974815 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 61 167 0 ENST00000261266.5:c.1924+1G>A p.X642_splice ENST00000261266 NM_002837.4 0 +PTPRC UCSF GRCh37 1 198725253 198725253 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 64 173 0 ENST00000442510.2:c.3864G>A p.Glu1288= p.E1288= ENST00000442510 1288 gaG/gaA 0 +PTPRCAP UCSF GRCh37 11 67203356 67203356 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 23 44 0 ENST00000326294.3:c.469G>A p.Gly157Ser p.G157S ENST00000326294 NM_005608.2 157 Ggc/Agc 0 +PTPRH UCSF GRCh37 19 55718105 55718105 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 68 186 0 ENST00000376350.3:c.304G>A p.Glu102Lys p.E102K ENST00000376350 NM_002842.3 102 Gag/Aag 0 +PTPRH UCSF GRCh37 19 55698945 55698945 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 64 135 0 ENST00000376350.3:c.2502G>A p.Gln834= p.Q834= ENST00000376350 NM_002842.3 834 caG/caA 0 +PTPRH UCSF GRCh37 19 55697841 55697841 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 47 142 0 ENST00000376350.3:c.2634C>T p.Ser878= p.S878= ENST00000376350 NM_002842.3 878 agC/agT 0 +PTPRK UCSF GRCh37 6 128399998 128399998 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 52 137 0 ENST00000368215.3:c.1843G>A p.Val615Ile p.V615I ENST00000368215 615 Gta/Ata 0 +PTPRK UCSF GRCh37 6 128306890 128306890 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 55 135 0 ENST00000368215.3:c.3224C>T p.Ala1075Val p.A1075V ENST00000368215 1075 gCt/gTt 0 +PTPRM UCSF GRCh37 18 7888373 7888373 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 66 146 0 ENST00000332175.8:c.466C>T p.Gln156Ter p.Q156* ENST00000332175 NM_002845.3 156 Cag/Tag 0 +PTPRM UCSF GRCh37 18 8394570 8394570 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 47 100 0 ENST00000332175.8:c.4266G>A p.Lys1422= p.K1422= ENST00000332175 NM_002845.3 1422 aaG/aaA 0 +PTPRU UCSF GRCh37 1 29605526 29605526 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 11 24 0 ENST00000345512.3:c.1456C>T p.Pro486Ser p.P486S ENST00000345512 NM_005704.4 486 Ccc/Tcc 0 +PTPRU UCSF GRCh37 1 29609209 29609209 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 21 40 0 ENST00000345512.3:c.1890G>A p.Glu630= p.E630= ENST00000345512 NM_005704.4 630 gaG/gaA 0 +PTPRZ1 UCSF GRCh37 7 121680878 121680878 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 39 78 0 ENST00000393386.2:c.5646G>A p.Gln1882= p.Q1882= ENST00000393386 NM_001206838.1 1882 caG/caA 0 +PUF60 UCSF GRCh37 8 144900217 144900217 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 167 32 95 0 ENST00000526683.1:c.632C>T p.Ala211Val p.A211V ENST00000526683 NM_001271098.1 211 gCc/gTc 0 +PURA UCSF GRCh37 5 139494246 139494246 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 23 42 0 ENST00000331327.3:c.480G>A p.Lys160= p.K160= ENST00000331327 NM_005859.4 160 aaG/aaA 0 +PUS7L UCSF GRCh37 12 44149022 44149022 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 61 114 0 ENST00000344862.5:c.27C>T p.Ile9= p.I9= ENST00000344862 NM_031292.4 9 atC/atT 0 +PVRL1 UCSF GRCh37 11 119549413 119549413 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 20 32 0 ENST00000264025.3:c.142G>A p.Val48Ile p.V48I ENST00000264025 NM_002855.4 48 Gtt/Att 0 +PVRL2 UCSF GRCh37 19 45389422 45389422 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 44 83 0 ENST00000252483.5:c.1293G>A p.Glu431= p.E431= ENST00000252483 NM_001042724.1 431 gaG/gaA 0 +PWP2 UCSF GRCh37 21 45534566 45534566 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 47 95 0 ENST00000291576.7:c.387G>A p.Arg129= p.R129= ENST00000291576 NM_005049.2 129 cgG/cgA 0 +PWWP2A UCSF GRCh37 5 159520808 159520808 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 124 111 237 0 ENST00000307063.7:c.849C>T p.Asn283= p.N283= ENST00000307063 NM_001130864.1 283 aaC/aaT 0 +QRFPR UCSF GRCh37 4 122254126 122254126 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 45 144 0 ENST00000394427.2:c.647C>T p.Thr216Ile p.T216I ENST00000394427 NM_198179.2 216 aCc/aTc 0 +R3HCC1 UCSF GRCh37 8 23146530 23146530 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 52 145 0 ENST00000411463.1:c.232G>A p.Val78Ile p.V78I ENST00000411463 78 Gtt/Att 0 +R3HDM1 UCSF GRCh37 2 136403068 136403068 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 78 187 0 ENST00000264160.4:c.1594C>T p.Gln532Ter p.Q532* ENST00000264160 NM_015361.2 532 Caa/Taa 0 +R3HDM2 UCSF GRCh37 12 57696963 57696963 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 52 116 0 ENST00000347140.3:c.203C>T p.Ala68Val p.A68V ENST00000347140 68 gCc/gTc 0 +RAB2B UCSF GRCh37 14 21936563 21936563 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 29 80 0 ENST00000397762.1:c.315G>A p.Arg105= p.R105= ENST00000397762 NM_032846.3 105 cgG/cgA 0 +RAB40B UCSF GRCh37 17 80616416 80616416 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 61 123 0 ENST00000571995.1:c.516G>A p.Arg172= p.R172= ENST00000571995 NM_006822.2 172 agG/agA 0 +RABGGTB UCSF GRCh37 1 76253239 76253239 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 51 151 0 ENST00000319942.3:c.61G>A p.Glu21Lys p.E21K ENST00000319942 NM_004582.3 21 Gag/Aag 0 +RABL2B UCSF GRCh37 22 51208342 51208342 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 1 32 104 0 ENST00000395598.3:c.400A>G p.Lys134Glu p.K134E ENST00000395598 NM_001130922.1 134 Aaa/Gaa 0 +RAC3 UCSF GRCh37 17 79991357 79991357 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 18 41 0 ENST00000306897.4:c.330C>T p.Ile110= p.I110= ENST00000306897 NM_005052.2 110 atC/atT 0 +RACGAP1 UCSF GRCh37 12 50393516 50393516 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 50 128 0 ENST00000312377.5:c.631G>A p.Gly211Arg p.G211R ENST00000312377 211 Ggg/Agg 0 +RAD1 UCSF GRCh37 5 34911848 34911848 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 97 189 0 ENST00000341754.4:c.377G>A p.Gly126Glu p.G126E ENST00000341754 126 gGa/gAa 0 +RAD18 UCSF GRCh37 3 9000665 9000665 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 67 139 0 ENST00000264926.2:c.72G>A p.Arg24= p.R24= ENST00000264926 NM_020165.3 24 cgG/cgA 0 +RAD21 UCSF GRCh37 8 117868523 117868532 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACCCACTGTA ACCCACTGTA CCCCCCTGT NOVEL P10_Rec Untested WXS Illumina HiSeq 6 0 ENST00000297338.2:c.815-5_819delinsACAGGGGGG p.X272_splice ENST00000297338 NM_006265.2 0 +RAD51 UCSF GRCh37 15 41023350 41023350 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 65 143 0 ENST00000267868.3:c.994G>A p.Asp332Asn p.D332N ENST00000267868 NM_002875.4 332 Gat/Aat 0 +RAD51C UCSF GRCh37 17 56772316 56772316 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 99 210 0 ENST00000337432.4:c.170C>T p.Ala57Val p.A57V ENST00000337432 NM_058216.2 57 gCc/gTc 0 +RAD52 UCSF GRCh37 12 1040430 1040430 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 53 119 0 ENST00000358495.3:c.142G>A p.Gly48Ser p.G48S ENST00000358495 NM_134424.2 48 Ggc/Agc 0 +RAD54B UCSF GRCh37 8 95412584 95412584 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 126 43 110 0 ENST00000336148.5:c.1052G>A p.Gly351Asp p.G351D ENST00000336148 NM_012415.3 351 gGc/gAc 0 +RAD54B UCSF GRCh37 8 95479653 95479653 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 296 92 177 0 ENST00000336148.5:c.115C>T p.Pro39Ser p.P39S ENST00000336148 NM_012415.3 39 Cca/Tca 0 +RALGAPA2 UCSF GRCh37 20 20585937 20585937 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 140 125 227 0 ENST00000202677.7:c.1920G>A p.Trp640Ter p.W640* ENST00000202677 NM_020343.3 640 tgG/tgA 0 +RALGAPA2 UCSF GRCh37 20 20505167 20505167 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 67 152 0 ENST00000202677.7:c.3783C>T p.Leu1261= p.L1261= ENST00000202677 NM_020343.3 1261 ctC/ctT 0 +RALGPS1 UCSF GRCh37 9 129961336 129961336 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 142 77 135 0 ENST00000259351.5:c.1238G>A p.Gly413Glu p.G413E ENST00000259351 NM_014636.2 413 gGg/gAg 0 +RANBP17 UCSF GRCh37 5 170343577 170343577 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 81 166 0 ENST00000523189.1:c.943G>A p.Glu315Lys p.E315K ENST00000523189 NM_022897.3 315 Gaa/Aaa 0 +RANBP17 UCSF GRCh37 5 170669776 170669776 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 101 214 0 ENST00000523189.1:c.2728G>A p.Val910Ile p.V910I ENST00000523189 NM_022897.3 910 Gta/Ata 0 +RANBP2 UCSF GRCh37 2 109384589 109384589 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 201 167 293 0 ENST00000283195.6:c.7594C>T p.Pro2532Ser p.P2532S ENST00000283195 NM_006267.4 2532 Cca/Tca 0 +RANBP6 UCSF GRCh37 9 6014933 6014933 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 98 202 0 ENST00000259569.5:c.675G>A p.Leu225= p.L225= ENST00000259569 NM_012416.3 225 ttG/ttA 0 +RANBP9 UCSF GRCh37 6 13711180 13711180 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 3 16 0 ENST00000011619.3:c.558G>A p.Arg186= p.R186= ENST00000011619 NM_005493.2 186 cgG/cgA 0 +RAP1A UCSF GRCh37 1 112240111 112240111 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 61 144 0 ENST00000356415.1:c.175G>A p.Ala59Thr p.A59T ENST00000356415 59 Gca/Aca 0 +RAP1GAP UCSF GRCh37 1 21938289 21938289 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 55 138 0 ENST00000374765.4:c.633C>T p.Phe211= p.F211= ENST00000374765 NM_002885.2 211 ttC/ttT 0 +RAPGEF6 UCSF GRCh37 5 130808360 130808360 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 41 121 0 ENST00000509018.1:c.2159C>T p.Pro720Leu p.P720L ENST00000509018 NM_016340.5 720 cCc/cTc 0 +RAPGEF6 UCSF GRCh37 5 130831301 130831301 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 44 115 0 ENST00000509018.1:c.1472G>A p.Gly491Asp p.G491D ENST00000509018 NM_016340.5 491 gGt/gAt 0 +RAPH1 UCSF GRCh37 2 204309628 204309628 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 61 171 2 ENST00000319170.5:c.1739C>T p.Ala580Val p.A580V ENST00000319170 NM_213589.1 580 gCc/gTc 0 +RASA3 UCSF GRCh37 13 114786977 114786977 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 22 67 0 ENST00000334062.7:c.688C>T p.Leu230Phe p.L230F ENST00000334062 NM_007368.2 230 Ctc/Ttc 0 +RASA3 UCSF GRCh37 13 114751087 114751087 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 50 130 0 ENST00000334062.7:c.2428C>T p.Gln810Ter p.Q810* ENST00000334062 NM_007368.2 810 Cag/Tag 0 +RASGEF1C UCSF GRCh37 5 179554648 179554648 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 15 38 0 ENST00000361132.4:c.675C>T p.Val225= p.V225= ENST00000361132 NM_175062.3 225 gtC/gtT 0 +RASGRF2 UCSF GRCh37 5 80369113 80369113 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 66 200 0 ENST00000265080.4:c.729G>A p.Lys243= p.K243= ENST00000265080 NM_006909.2 243 aaG/aaA 0 +RASGRP4 UCSF GRCh37 19 38905542 38905542 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 21 33 0 ENST00000587738.1:c.1176C>T p.Leu392= p.L392= ENST00000587738 392 ctC/ctT 0 +RASSF2 UCSF GRCh37 20 4766911 4766911 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 89 201 0 ENST00000379376.2:c.877G>A p.Glu293Lys p.E293K ENST00000379376 NM_170774.1 293 Gaa/Aaa 0 +RBCK1 UCSF GRCh37 20 409726 409726 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 16 37 0 ENST00000356286.5:c.1440C>T p.Arg480= p.R480= ENST00000356286 NM_031229.2 480 cgC/cgT 0 +RBFA UCSF GRCh37 18 77794524 77794524 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 14 9 0 ENST00000306735.5:c.29G>A p.Arg10His p.R10H ENST00000306735 NM_024805.2 10 cGc/cAc 0 +RBKS UCSF GRCh37 2 28050538 28050538 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 46 89 0 ENST00000302188.3:c.691G>A p.Val231Met p.V231M ENST00000302188 NM_022128.1 231 Gtg/Atg 0 +RBL1 UCSF GRCh37 20 35632224 35632224 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 63 127 0 ENST00000373664.3:c.2917C>T p.Pro973Ser p.P973S ENST00000373664 NM_002895.3 973 Cca/Tca 0 +RBL1 UCSF GRCh37 20 35717525 35717525 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 74 154 0 ENST00000373664.3:c.157G>A p.Gly53Arg p.G53R ENST00000373664 NM_002895.3 53 Gga/Aga 0 +RBM10 UCSF GRCh37 X 47041020 47041020 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 22 48 0 ENST00000377604.3:c.1550G>A p.Ser517Asn p.S517N ENST00000377604 NM_001204468.1 517 aGc/aAc 0 +RBM12B UCSF GRCh37 8 94746508 94746508 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 225 87 157 0 ENST00000399300.2:c.2131C>T p.Pro711Ser p.P711S ENST00000399300 NM_203390.2 711 Cct/Tct 0 +RBM14 UCSF GRCh37 11 66391790 66391790 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 70 116 0 ENST00000310137.4:c.443C>T p.Thr148Ile p.T148I ENST00000310137 NM_006328.3 148 aCc/aTc 0 +RBM20 UCSF GRCh37 10 112581121 112581121 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 53 127 0 ENST00000369519.3:c.2744G>A p.Gly915Glu p.G915E ENST00000369519 NM_001134363.1 915 gGg/gAg 0 +RBM25 UCSF GRCh37 14 73544137 73544137 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 54 110 0 ENST00000261973.7:c.217G>A p.Gly73Ser p.G73S ENST00000261973 NM_021239.2 73 Ggc/Agc 0 +RBM33 UCSF GRCh37 7 155530819 155530819 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 127 194 0 ENST00000401878.3:c.1459C>T p.Pro487Ser p.P487S ENST00000401878 NM_053043.2 487 Ccg/Tcg 0 +RBM45 UCSF GRCh37 2 178988377 178988377 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 62 143 0 ENST00000286070.5:c.982G>A p.Asp328Asn p.D328N ENST00000286070 NM_152945.2 328 Gat/Aat 0 +RBMXL3 UCSF GRCh37 X 114425911 114425911 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 33 88 0 ENST00000424776.3:c.1907G>A p.Arg636His p.R636H ENST00000424776 NM_001145346.1 636 cGc/cAc 0 +RC3H2 UCSF GRCh37 9 125616365 125616365 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 236 98 179 0 ENST00000357244.2:c.2983G>A p.Ala995Thr p.A995T ENST00000357244 NM_001100588.1 995 Gcc/Acc 0 +RCAN3 UCSF GRCh37 1 24859647 24859647 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 32 103 0 ENST00000374395.4:c.444C>T p.Ser148= p.S148= ENST00000374395 NM_001251984.1 148 tcC/tcT 0 +RECQL4 UCSF GRCh37 8 145740731 145740731 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 166 36 67 0 ENST00000428558.2:c.1369G>A p.Gly457Arg p.G457R ENST00000428558 NM_004260.3 457 Ggg/Agg 0 +RECQL4 UCSF GRCh37 8 145741398 145741398 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 250 44 96 0 ENST00000428558.2:c.1105C>T p.Leu369Phe p.L369F ENST00000428558 NM_004260.3 369 Ctc/Ttc 0 +RECQL5 UCSF GRCh37 17 73625500 73625500 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 35 69 0 ENST00000317905.5:c.2003C>T p.Thr668Met p.T668M ENST00000317905 NM_004259.6 668 aCg/aTg 0 +REEP6 UCSF GRCh37 19 1496425 1496425 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 23 55 0 ENST00000233596.3:c.490G>A p.Asp164Asn p.D164N ENST00000233596 NM_138393.1 164 Gac/Aac 0 +RELN UCSF GRCh37 7 103363610 103363610 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 32 103 0 ENST00000428762.1:c.782C>T p.Ala261Val p.A261V ENST00000428762 NM_005045.3 261 gCt/gTt 0 +RENBP UCSF GRCh37 X 153209422 153209422 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 21 27 0 ENST00000393700.3:c.214G>A p.Val72Ile p.V72I ENST00000393700 NM_002910.5 72 Gta/Ata 0 +REST UCSF GRCh37 4 57798062 57798062 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 67 135 0 ENST00000309042.7:c.3038G>A p.Ser1013Asn p.S1013N ENST00000309042 NM_005612.4 1013 aGc/aAc 0 +RET UCSF GRCh37 10 43597907 43597907 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 41 106 0 ENST00000355710.3:c.455C>T p.Thr152Ile p.T152I ENST00000355710 NM_020975.4 152 aCc/aTc 0 +REXO4 UCSF GRCh37 9 136282832 136282832 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 194 106 180 0 ENST00000371942.3:c.133G>A p.Val45Ile p.V45I ENST00000371942 NM_001279350.1 45 Gta/Ata 0 +RFC5 UCSF GRCh37 12 118464746 118464746 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 84 171 0 ENST00000454402.2:c.716C>T p.Thr239Ile p.T239I ENST00000454402 NM_007370.5 239 aCc/aTc 0 +RFNG UCSF GRCh37 17 80007572 80007572 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 11 14 0 ENST00000310496.4:c.809C>T p.Pro270Leu p.P270L ENST00000310496 NM_002917.1 270 cCc/cTc 0 +RFTN1 UCSF GRCh37 3 16411748 16411748 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 102 258 0 ENST00000334133.4:c.865C>T p.His289Tyr p.H289Y ENST00000334133 NM_015150.1 289 Cat/Tat 0 +RFWD2 UCSF GRCh37 1 176012861 176012861 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 67 185 0 ENST00000367669.3:c.1515G>A p.Arg505= p.R505= ENST00000367669 NM_022457.5 505 agG/agA 0 +RFX7 UCSF GRCh37 15 56471467 56471467 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 18 8 45 0 ENST00000559447.2:c.-97+1G>A p.X33_splice ENST00000559447 0 +RFX7 UCSF GRCh37 15 56435014 56435014 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 120 180 0 ENST00000559447.2:c.72G>A p.Glu24= p.E24= ENST00000559447 24 gaG/gaA 0 +RGL3 UCSF GRCh37 19 11516053 11516053 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 22 28 0 ENST00000380456.3:c.1046C>T p.Ala349Val p.A349V ENST00000380456 NM_001035223.2 349 gCc/gTc 0 +RGS4 UCSF GRCh37 1 163044336 163044336 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 86 163 1 ENST00000367909.6:c.604C>T p.Pro202Ser p.P202S ENST00000367909 NM_005613.5 202 Cct/Tct 0 +RGS8 UCSF GRCh37 1 182617280 182617280 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 136 113 203 0 ENST00000367556.1:c.352C>T p.Pro118Ser p.P118S ENST00000367556 118 Cca/Tca 0 +RHPN1 UCSF GRCh37 8 144458815 144458815 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 11 20 0 ENST00000289013.6:c.297G>A p.Arg99= p.R99= ENST00000289013 NM_052924.2 99 cgG/cgA 0 +RHPN1 UCSF GRCh37 8 144460928 144460928 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 30 29 0 ENST00000289013.6:c.522G>A p.Gln174= p.Q174= ENST00000289013 NM_052924.2 174 caG/caA 0 +RIMBP3 UCSF GRCh37 22 20457152 20457152 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 150 70 207 0 ENST00000426804.1:c.4150G>A p.Glu1384Lys p.E1384K ENST00000426804 NM_015672.1 1384 Gag/Aag 0 +RING1 UCSF GRCh37 6 33177691 33177691 + splice_acceptor_variant Splice_Site SNP G G T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 35 101 0 ENST00000374656.4:c.240-1G>T p.X80_splice ENST00000374656 NM_002931.3 0 +RIOK3 UCSF GRCh37 18 21059389 21059389 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 32 98 0 ENST00000339486.3:c.1452+1G>A p.X484_splice ENST00000339486 NM_003831.3 0 +RIPK3 UCSF GRCh37 14 24805454 24805454 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 56 141 0 ENST00000216274.5:c.1484G>A p.Gly495Asp p.G495D ENST00000216274 NM_006871.3 495 gGt/gAt 0 +RIPK4 UCSF GRCh37 21 43169343 43169343 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 41 128 0 ENST00000352483.2:c.644G>A p.Gly215Asp p.G215D ENST00000352483 215 gGc/gAc 0 +RIPPLY1 UCSF GRCh37 X 106146371 106146371 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 49 102 0 ENST00000276173.4:c.147G>A p.Gly49= p.G49= ENST00000276173 NM_138382.2 49 ggG/ggA 0 +RIPPLY1 UCSF GRCh37 X 106146449 106146449 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 39 103 0 ENST00000276173.4:c.69C>T p.Asp23= p.D23= ENST00000276173 NM_138382.2 23 gaC/gaT 0 +RIT1 UCSF GRCh37 1 155874248 155874248 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 57 113 0 ENST00000368323.3:c.283G>A p.Gly95Arg p.G95R ENST00000368323 NM_006912.5 95 Ggg/Agg 0 +RLF UCSF GRCh37 1 40704129 40704129 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 74 166 0 ENST00000372771.4:c.3755G>A p.Ser1252Asn p.S1252N ENST00000372771 NM_012421.3 1252 aGt/aAt 0 +RMI1 UCSF GRCh37 9 86617645 86617645 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 179 90 170 0 ENST00000325875.3:c.1744C>T p.Gln582Ter p.Q582* ENST00000325875 NM_024945.2 582 Caa/Taa 0 +RNASE1 UCSF GRCh37 14 21269809 21269809 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 72 132 0 ENST00000340900.3:c.419G>A p.Gly140Glu p.G140E ENST00000340900 NM_198234.2 140 gGg/gAg 0 +RNASEL UCSF GRCh37 1 182551378 182551378 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 69 165 0 ENST00000367559.3:c.1582G>A p.Val528Ile p.V528I ENST00000367559 NM_021133.3 528 Gtc/Atc 0 +RNF11 UCSF GRCh37 1 51702498 51702498 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 20 53 0 ENST00000242719.3:c.70G>A p.Ala24Thr p.A24T ENST00000242719 NM_014372.4 24 Gct/Act 0 +RNF19A UCSF GRCh37 8 101281054 101281054 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 185 60 142 0 ENST00000341084.2:c.1150C>T p.Pro384Ser p.P384S ENST00000341084 NM_183419.3 384 Cct/Tct 0 +RNF208 UCSF GRCh37 9 140115417 140115417 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 4 17 0 ENST00000391553.1:c.248C>T p.Pro83Leu p.P83L ENST00000391553 NM_031297.4 83 cCt/cTt 0 +RNF213 UCSF GRCh37 17 78318527 78318527 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 95 197 0 ENST00000582970.1:c.6392C>T p.Thr2131Ile p.T2131I ENST00000582970 NM_001256071.1 2131 aCc/aTc 0 +RNF217 UCSF GRCh37 6 125398004 125398004 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 72 162 0 ENST00000521654.2:c.1483G>A p.Ala495Thr p.A495T ENST00000521654 NM_001286398.1 495 Gct/Act 0 +RNF31 UCSF GRCh37 14 24618685 24618685 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 54 130 0 ENST00000324103.6:c.702G>A p.Gln234= p.Q234= ENST00000324103 NM_017999.4 234 caG/caA 0 +RNF38 UCSF GRCh37 9 36390546 36390546 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 295 97 186 0 ENST00000259605.6:c.80G>A p.Arg27Lys p.R27K ENST00000259605 NM_022781.4 27 aGa/aAa 0 +RNF40 UCSF GRCh37 16 30780214 30780214 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 53 116 0 ENST00000324685.6:c.2153G>A p.Ser718Asn p.S718N ENST00000324685 NM_014771.3 718 aGc/aAc 0 +RNF43 UCSF GRCh37 17 56436066 56436066 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 5 10 0 ENST00000407977.2:c.1071C>T p.Tyr357= p.Y357= ENST00000407977 357 taC/taT 0 +ROBO3 UCSF GRCh37 11 124747872 124747872 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 19 55 0 ENST00000397801.1:c.3026G>A p.Gly1009Asp p.G1009D ENST00000397801 NM_022370.3 1009 gGc/gAc 0 +RORA UCSF GRCh37 15 60803566 60803566 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 77 161 0 ENST00000335670.6:c.679C>T p.Pro227Ser p.P227S ENST00000335670 NM_134261.2 227 Cct/Tct 0 +RP1 UCSF GRCh37 8 55537248 55537248 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 64 172 0 ENST00000220676.1:c.806C>T p.Ser269Leu p.S269L ENST00000220676 NM_006269.1 269 tCa/tTa 0 +RP1 UCSF GRCh37 8 55539071 55539071 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 72 128 0 ENST00000220676.1:c.2629G>A p.Val877Met p.V877M ENST00000220676 NM_006269.1 877 Gtg/Atg 0 +RP2 UCSF GRCh37 X 46713551 46713551 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 61 132 0 ENST00000218340.3:c.743C>T p.Ala248Val p.A248V ENST00000218340 NM_006915.2 248 gCa/gTa 0 +RPA1 UCSF GRCh37 17 1775757 1775757 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 24 42 0 ENST00000254719.5:c.391G>A p.Ala131Thr p.A131T ENST00000254719 NM_002945.3 131 Gcg/Acg 0 +RPAP1 UCSF GRCh37 15 41813134 41813134 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 41 58 0 ENST00000304330.4:c.3250G>A p.Val1084Ile p.V1084I ENST00000304330 NM_015540.2 1084 Gtc/Atc 0 +RPE UCSF GRCh37 2 210880814 210880814 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 55 57 138 0 ENST00000359429.6:c.320A>G p.Asp107Gly p.D107G ENST00000359429 NM_199229.2 107 gAc/gGc 0 +RPGRIP1L UCSF GRCh37 16 53692758 53692758 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 32 82 0 ENST00000379925.3:c.1276G>A p.Glu426Lys p.E426K ENST00000379925 NM_015272.2 426 Gaa/Aaa 0 +RPL18 UCSF GRCh37 19 49119203 49119203 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 22 49 0 ENST00000549920.1:c.422G>A p.Gly141Asp p.G141D ENST00000549920 NM_000979.3 141 gGt/gAt 0 +RPL23 UCSF GRCh37 17 37006395 37006395 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 44 105 0 ENST00000394332.1:c.413G>A p.Ser138Asn p.S138N ENST00000394332 138 aGc/aAc 0 +RPL8 UCSF GRCh37 8 146016857 146016857 + missense_variant Missense_Mutation SNP G G A snp132_rs11539887 P10_Rec somatic WXS Sanger Illumina HiSeq 120 29 60 0 ENST00000262584.3:c.304C>T p.Leu102Phe p.L102F ENST00000262584 NM_000973.3 102 Ctc/Ttc 0 +RPL8 UCSF GRCh37 8 146016729 146016729 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 179 37 83 0 ENST00000262584.3:c.432G>A p.Lys144= p.K144= ENST00000262584 NM_000973.3 144 aaG/aaA 0 +RPS2 UCSF GRCh37 16 2012774 2012774 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 29 63 0 ENST00000343262.4:c.512G>A p.Gly171Glu p.G171E ENST00000343262 NM_002952.3 171 gGg/gAg 0 +RQCD1 UCSF GRCh37 2 219458860 219458860 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 50 129 0 ENST00000273064.6:c.761C>T p.Pro254Leu p.P254L ENST00000273064 NM_005444.2 254 cCt/cTt 0 +RRBP1 UCSF GRCh37 20 17594837 17594837 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 40 107 0 ENST00000377807.2:c.2924C>T p.Thr975Ile p.T975I ENST00000377807 NM_001042576.1 975 aCc/aTc 0 +RRN3 UCSF GRCh37 16 15188002 15188002 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 11 23 0 ENST00000198767.6:c.89G>A p.Gly30Glu p.G30E ENST00000198767 NM_018427.3 30 gGg/gAg 0 +RRP1 UCSF GRCh37 21 45212611 45212611 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 63 139 0 ENST00000497547.1:c.274+1G>A p.X92_splice ENST00000497547 NM_003683.5 0 +RRP15 UCSF GRCh37 1 218480886 218480886 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 41 124 0 ENST00000366932.3:c.617C>T p.Ser206Phe p.S206F ENST00000366932 NM_016052.3 206 tCc/tTc 0 +RSAD1 UCSF GRCh37 17 48562189 48562189 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 35 47 0 ENST00000258955.2:c.1296G>A p.Gln432= p.Q432= ENST00000258955 NM_018346.1 432 caG/caA 0 +RSG1 UCSF GRCh37 1 16558551 16558551 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 46 91 0 ENST00000375599.3:c.769C>T p.Pro257Ser p.P257S ENST00000375599 NM_030907.3 257 Cct/Tct 0 +RSPO1 UCSF GRCh37 1 38095290 38095290 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 29 49 0 ENST00000356545.2:c.44C>T p.Thr15Met p.T15M ENST00000356545 NM_001038633.3 15 aCg/aTg 0 +RSPO2 UCSF GRCh37 8 109001403 109001403 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 206 69 156 0 ENST00000276659.5:c.164G>A p.Cys55Tyr p.C55Y ENST00000276659 NM_178565.4 55 tGt/tAt 0 +RTN4 UCSF GRCh37 2 55252930 55252930 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 73 182 0 ENST00000337526.6:c.2305G>A p.Glu769Lys p.E769K ENST00000337526 NM_020532.4 769 Gaa/Aaa 0 +RTP1 UCSF GRCh37 3 186917483 186917483 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 35 76 0 ENST00000312295.4:c.417G>A p.Arg139= p.R139= ENST00000312295 NM_153708.2 139 cgG/cgA 0 +RTTN UCSF GRCh37 18 67781812 67781812 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 73 182 0 ENST00000255674.6:c.3552C>T p.Leu1184= p.L1184= ENST00000255674 NM_173630.3 1184 ctC/ctT 0 +RUFY3 UCSF GRCh37 4 71634350 71634350 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 91 187 1 ENST00000226328.4:c.668G>A p.Cys223Tyr p.C223Y ENST00000226328 NM_014961.3 223 tGt/tAt 0 +RUSC2 UCSF GRCh37 9 35547678 35547678 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 104 166 0 ENST00000361226.3:c.1160C>T p.Ala387Val p.A387V ENST00000361226 NM_014806.2 387 gCc/gTc 0 +RWDD1 UCSF GRCh37 6 116914127 116914161 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TGGTTGCCTTTTGCAGCTGGAAACAACGTGGAGGT TGGTTGCCTTTTGCAGCTGGAAACAACGTGGAGGT GGTTGCCTTTTGCAGCTGGAAAAAACGGGGGGGG NOVEL P10_Rec Untested WXS Illumina HiSeq 6 0 ENST00000466444.2:c.611-16_629delinsGGTTGCCTTTTGCAGCTGGAAAAAACGGGGGGGG p.X204_splice ENST00000466444 NM_015952.2 0 +RXFP3 UCSF GRCh37 5 33937149 33937149 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 53 90 0 ENST00000330120.3:c.304G>A p.Val102Ile p.V102I ENST00000330120 NM_016568.3 102 Gtt/Att 0 +RXRG UCSF GRCh37 1 165386444 165386444 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 43 150 0 ENST00000359842.5:c.456G>A p.Gly152= p.G152= ENST00000359842 NM_001256570.1 152 ggG/ggA 0 +RYK UCSF GRCh37 3 133941301 133941301 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 50 120 0 ENST00000296084.4:c.309G>A p.Glu103= p.E103= ENST00000296084 NM_001005861.2 103 gaG/gaA 0 +RYR1 UCSF GRCh37 19 38980901 38980901 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 39 69 0 ENST00000359596.3:c.6000C>T p.Ser2000= p.S2000= ENST00000359596 2000 tcC/tcT 0 +RYR2 UCSF GRCh37 1 237837510 237837510 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 82 181 0 ENST00000366574.2:c.8705C>T p.Ala2902Val p.A2902V ENST00000366574 NM_001035.2 2902 gCt/gTt 0 +RYR3 UCSF GRCh37 15 33954719 33954719 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 72 167 0 ENST00000389232.4:c.4988C>T p.Pro1663Leu p.P1663L ENST00000389232 NM_001036.3 1663 cCc/cTc 0 +RYR3 UCSF GRCh37 15 33833074 33833074 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 69 135 0 ENST00000389232.4:c.629G>A p.Gly210Glu p.G210E ENST00000389232 NM_001036.3 210 gGa/gAa 0 +S100PBP UCSF GRCh37 1 33292145 33292145 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 86 175 0 ENST00000373475.5:c.445G>T p.Ala149Ser p.A149S ENST00000373475 NM_022753.3 149 Gca/Tca 0 +S100PBP UCSF GRCh37 1 33293638 33293638 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 46 146 0 ENST00000373475.5:c.876G>A p.Glu292= p.E292= ENST00000373475 NM_022753.3 292 gaG/gaA 0 +S1PR3 UCSF GRCh37 9 91616800 91616800 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 45 102 0 ENST00000358157.2:c.685G>A p.Val229Met p.V229M ENST00000358157 NM_005226.3 229 Gtg/Atg 0 +SAFB UCSF GRCh37 19 5653129 5653129 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 38 95 0 ENST00000292123.5:c.1297G>A p.Val433Met p.V433M ENST00000292123 NM_002967.3 433 Gtg/Atg 0 +SALL1 UCSF GRCh37 16 51173853 51173853 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 76 105 0 ENST00000251020.4:c.2280C>T p.Pro760= p.P760= ENST00000251020 NM_002968.2 760 ccC/ccT 0 +SAMSN1 UCSF GRCh37 21 15858298 15858298 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 73 193 0 ENST00000400566.1:c.1057G>A p.Asp353Asn p.D353N ENST00000400566 NM_022136.4 353 Gat/Aat 0 +SBF1 UCSF GRCh37 22 50893548 50893548 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 55 58 0 ENST00000380817.3:c.4578G>A p.Glu1526= p.E1526= ENST00000380817 NM_002972.2 1526 gaG/gaA 0 +SBNO2 UCSF GRCh37 19 1122245 1122245 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 11 22 0 ENST00000361757.3:c.1042C>T p.Leu348Phe p.L348F ENST00000361757 NM_014963.2 348 Ctc/Ttc 0 +SCAF8 UCSF GRCh37 6 155145427 155145427 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 113 192 0 ENST00000367178.3:c.1986G>A p.Ser662= p.S662= ENST00000367178 NM_014892.3 662 tcG/tcA 0 +SCAI UCSF GRCh37 9 127791974 127791974 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 35 105 0 ENST00000336505.6:c.275G>A p.Gly92Glu p.G92E ENST00000336505 NM_001144877.2 92 gGa/gAa 0 +SCARA3 UCSF GRCh37 8 27516123 27516123 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 81 152 0 ENST00000301904.3:c.436C>T p.Gln146Ter p.Q146* ENST00000301904 NM_016240.2 146 Cag/Tag 0 +SCARF2 UCSF GRCh37 22 20780139 20780139 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 12 12 0 ENST00000266214.5:c.2139G>A p.Thr713= p.T713= ENST00000266214 NM_153334.4 713 acG/acA 0 +SCARF2 UCSF GRCh37 22 20783609 20783609 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 20 44 0 ENST00000266214.5:c.1458G>A p.Arg486= p.R486= ENST00000266214 NM_153334.4 486 agG/agA 0 +SCEL UCSF GRCh37 13 78182190 78182190 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 2 40 92 0 ENST00000349847.3:c.1158-1G>A p.X386_splice ENST00000349847 NM_144777.2 0 +SCFD1 UCSF GRCh37 14 31204805 31204805 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 50 114 0 ENST00000458591.2:c.1919G>A p.Gly640Glu p.G640E ENST00000458591 NM_016106.3 640 gGa/gAa 0 +SCG2 UCSF GRCh37 2 224463348 224463348 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 123 98 221 0 ENST00000305409.2:c.653G>A p.Arg218Lys p.R218K ENST00000305409 NM_003469.4 218 aGg/aAg 0 +SCG2 UCSF GRCh37 2 224463362 224463362 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 128 108 248 0 ENST00000305409.2:c.639C>T p.Asn213= p.N213= ENST00000305409 NM_003469.4 213 aaC/aaT 0 +SCGB1A1 UCSF GRCh37 11 62189706 62189706 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 66 115 0 ENST00000278282.2:c.69C>T p.Ile23= p.I23= ENST00000278282 NM_003357.4 23 atC/atT 0 +SCN11A UCSF GRCh37 3 38938584 38938584 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 62 117 0 ENST00000302328.3:c.2155G>A p.Gly719Ser p.G719S ENST00000302328 NM_014139.2 719 Ggc/Agc 0 +SCN2A UCSF GRCh37 2 166237114 166237114 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 49 140 0 ENST00000283256.6:c.4321C>T p.Pro1441Ser p.P1441S ENST00000283256 NM_021007.2 1441 Ccc/Tcc 0 +SCN3A UCSF GRCh37 2 166018830 166018830 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 84 94 0 ENST00000360093.3:c.1019G>A p.Gly340Asp p.G340D ENST00000360093 NM_001081677.1 340 gGc/gAc 0 +SCN4A UCSF GRCh37 17 62028875 62028875 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 72 134 0 ENST00000435607.1:c.2762C>T p.Thr921Ile p.T921I ENST00000435607 NM_000334.4 921 aCc/aTc 0 +SCN8A UCSF GRCh37 12 52162792 52162792 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 97 196 0 ENST00000354534.6:c.3045G>A p.Val1015= p.V1015= ENST00000354534 NM_014191.3 1015 gtG/gtA 0 +SCNN1A UCSF GRCh37 12 6471222 6471222 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 50 117 0 ENST00000228916.2:c.870C>T p.Asn290= p.N290= ENST00000228916 NM_001038.5 290 aaC/aaT 0 +SCRIB UCSF GRCh37 8 144896224 144896224 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 8 11 0 ENST00000320476.3:c.224C>T p.Pro75Leu p.P75L ENST00000320476 NM_015356.4 75 cCt/cTt 0 +SCRIB UCSF GRCh37 8 144888643 144888643 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 8 15 0 ENST00000320476.3:c.2280C>T p.Ile760= p.I760= ENST00000320476 NM_015356.4 760 atC/atT 0 +SCRIB UCSF GRCh37 8 144891862 144891862 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 164 41 62 0 ENST00000320476.3:c.1557C>T p.Gly519= p.G519= ENST00000320476 NM_015356.4 519 ggC/ggT 0 +SDCCAG3 UCSF GRCh37 9 139301920 139301920 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 22 36 0 ENST00000357365.3:c.496G>A p.Asp166Asn p.D166N ENST00000357365 NM_001039707.1 166 Gat/Aat 0 +SDCCAG8 UCSF GRCh37 1 243542141 243542141 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 69 137 0 ENST00000366541.3:c.1592C>T p.Ser531Phe p.S531F ENST00000366541 NM_006642.3 531 tCt/tTt 0 +SDK1 UCSF GRCh37 7 4185534 4185534 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 34 58 0 ENST00000404826.2:c.4409C>T p.Thr1470Ile p.T1470I ENST00000404826 NM_152744.3 1470 aCc/aTc 0 +SDK1 UCSF GRCh37 7 3991372 3991372 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 33 92 0 ENST00000404826.2:c.970G>A p.Asp324Asn p.D324N ENST00000404826 NM_152744.3 324 Gac/Aac 0 +SDK2 UCSF GRCh37 17 71429901 71429901 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 54 90 0 ENST00000392650.3:c.1282G>A p.Ala428Thr p.A428T ENST00000392650 NM_001144952.1 428 Gcg/Acg 0 +SDR42E1 UCSF GRCh37 16 82033718 82033718 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 105 88 224 0 ENST00000328945.5:c.180C>T p.His60= p.H60= ENST00000328945 NM_145168.2 60 caC/caT 0 +SEC16A UCSF GRCh37 9 139369238 139369238 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 208 92 199 0 ENST00000313050.7:c.2830G>A p.Asp944Asn p.D944N ENST00000313050 NM_014866.1 944 Gat/Aat 0 +SEC16A UCSF GRCh37 9 139350212 139350212 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 18 30 0 ENST00000313050.7:c.5698C>T p.Leu1900Phe p.L1900F ENST00000313050 NM_014866.1 1900 Ctc/Ttc 0 +SEC16A UCSF GRCh37 9 139351971 139351971 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 47 94 0 ENST00000313050.7:c.5475C>T p.Tyr1825= p.Y1825= ENST00000313050 NM_014866.1 1825 taC/taT 0 +SEC23A UCSF GRCh37 14 39532540 39532540 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 23 67 0 ENST00000307712.6:c.1386G>A p.Glu462= p.E462= ENST00000307712 NM_006364.2 462 gaG/gaA 0 +SEC24C UCSF GRCh37 10 75530134 75530134 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 117 234 0 ENST00000339365.2:c.2959C>T p.Leu987Phe p.L987F ENST00000339365 NM_004922.3 987 Ctc/Ttc 0 +SEC24C UCSF GRCh37 10 75510875 75510875 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 45 87 0 ENST00000339365.2:c.182G>A p.Arg61Lys p.R61K ENST00000339365 NM_004922.3 61 aGa/aAa 0 +SEC61B UCSF GRCh37 9 101984832 101984832 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 26 38 0 ENST00000223641.4:c.8G>A p.Gly3Asp p.G3D ENST00000223641 NM_006808.2 3 gGt/gAt 0 +SECTM1 UCSF GRCh37 17 80280234 80280234 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 37 56 0 ENST00000269389.3:c.550C>T p.Leu184Phe p.L184F ENST00000269389 NM_003004.2 184 Ctc/Ttc 0 +SELO UCSF GRCh37 22 50649208 50649208 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 5 79 92 0 ENST00000380903.2:c.1219G>A p.Ala407Thr p.A407T ENST00000380903 NM_031454.1 407 Gcc/Acc 0 +SEMA3E UCSF GRCh37 7 82997288 82997288 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 70 137 0 ENST00000307792.3:c.1942G>A p.Asp648Asn p.D648N ENST00000307792 NM_012431.2 648 Gat/Aat 0 +SEMA3F UCSF GRCh37 3 50219793 50219793 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 60 137 0 ENST00000002829.3:c.720G>A p.Gln240= p.Q240= ENST00000002829 NM_004186.3 240 caG/caA 0 +SEMA4B UCSF GRCh37 15 90771584 90771584 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 57 98 0 ENST00000411539.2:c.2223G>A p.Arg741= p.R741= ENST00000411539 NM_198925.2 741 cgG/cgA 0 +SEMA4C UCSF GRCh37 2 97533552 97533552 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 58 121 0 ENST00000305476.5:c.72G>A p.Trp24Ter p.W24* ENST00000305476 NM_017789.4 24 tgG/tgA 0 +SEMA6A UCSF GRCh37 5 115782564 115782564 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 53 115 0 ENST00000343348.6:c.2838C>T p.His946= p.H946= ENST00000343348 NM_020796.3 946 caC/caT 0 +SENP1 UCSF GRCh37 12 48458896 48458896 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P10_Rec Untested WXS Illumina HiSeq 68 0 ENST00000448372.1:c.1227delA p.Gly410ValfsTer4 p.G410Vfs*4 ENST00000448372 NM_001267595.1 409 aaA/aa 0 +SENP1 UCSF GRCh37 12 48441857 48441857 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 53 161 0 ENST00000448372.1:c.1618G>A p.Asp540Asn p.D540N ENST00000448372 NM_001267595.1 540 Gac/Aac 0 +SERAC1 UCSF GRCh37 6 158551514 158551514 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 25 60 0 ENST00000367104.3:c.743G>A p.Gly248Asp p.G248D ENST00000367104 NM_032861.3 248 gGt/gAt 0 +SERPINA11 UCSF GRCh37 14 94914727 94914727 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 110 182 0 ENST00000334708.3:c.385C>T p.Pro129Ser p.P129S ENST00000334708 NM_001080451.1 129 Ccc/Tcc 0 +SERPINH1 UCSF GRCh37 11 75277902 75277902 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 38 75 0 ENST00000358171.3:c.508C>T p.Leu170= p.L170= ENST00000358171 NM_001235.3 170 Ctg/Ttg 0 +SERPINI2 UCSF GRCh37 3 167159929 167159929 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 27 87 0 ENST00000264677.4:c.1186G>A p.Glu396Lys p.E396K ENST00000264677 396 Gag/Aag 0 +SESN2 UCSF GRCh37 1 28601468 28601468 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 57 99 0 ENST00000253063.3:c.1153G>A p.Asp385Asn p.D385N ENST00000253063 NM_031459.4 385 Gac/Aac 0 +SETD1A UCSF GRCh37 16 30977210 30977210 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 58 100 0 ENST00000262519.8:c.2008G>A p.Gly670Arg p.G670R ENST00000262519 NM_014712.1 670 Ggg/Agg 0 +SETD1B UCSF GRCh37 12 122261376 122261376 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 9 16 0 ENST00000604567.1:c.4891G>A p.Glu1631Lys p.E1631K ENST00000604567 1631 Gaa/Aaa 0 +SEZ6 UCSF GRCh37 17 27286234 27286234 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.000,snp132_rs117276370 P10_Rec Untested WXS Illumina HiSeq 68 74 125 1 ENST00000317338.12:c.1916G>A p.Arg639His p.R639H ENST00000317338 639 cGc/cAc 0 +SF1 UCSF GRCh37 11 64533474 64533474 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 13 14 0 ENST00000377390.3:c.1736C>T p.Pro579Leu p.P579L ENST00000377390 NM_004630.3 579 cCt/cTt 0 +SF3A1 UCSF GRCh37 22 30741012 30741012 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 111 163 0 ENST00000215793.8:c.561G>A p.Gln187= p.Q187= ENST00000215793 NM_005877.4 187 caG/caA 0 +SF3B3 UCSF GRCh37 16 70566422 70566422 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 95 198 0 ENST00000302516.5:c.611C>T p.Thr204Ile p.T204I ENST00000302516 NM_012426.4 204 aCc/aTc 0 +SGK1 UCSF GRCh37 6 134528570 134528570 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 70 167 0 ENST00000367858.5:c.286-1G>A p.X96_splice ENST00000367858 NM_001143676.1 0 +SGPL1 UCSF GRCh37 10 72631678 72631678 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 51 116 0 ENST00000373202.3:c.994C>T p.Pro332Ser p.P332S ENST00000373202 NM_003901.3 332 Cca/Tca 0 +SGPP1 UCSF GRCh37 14 64153035 64153035 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 81 184 0 ENST00000247225.6:c.1114G>A p.Gly372Arg p.G372R ENST00000247225 NM_030791.2 372 Ggg/Agg 0 +SH2B1 UCSF GRCh37 16 28877820 28877820 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 42 89 0 ENST00000322610.8:c.405C>T p.Ser135= p.S135= ENST00000322610 135 tcC/tcT 0 +SH2D5 UCSF GRCh37 1 21050210 21050210 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 13 26 0 ENST00000444387.2:c.817G>A p.Ala273Thr p.A273T ENST00000444387 NM_001103161.1 273 Gca/Aca 0 +SH3BP4 UCSF GRCh37 2 235949623 235949623 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 66 140 0 ENST00000344528.4:c.210C>T p.Asn70= p.N70= ENST00000344528 70 aaC/aaT 0 +SH3GLB2 UCSF GRCh37 9 131777142 131777142 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 134 67 157 0 ENST00000372559.1:c.376G>A p.Gly126Arg p.G126R ENST00000372559 NM_001287046.1 126 Gga/Aga 0 +SH3GLB2 UCSF GRCh37 9 131772104 131772104 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 13 27 0 ENST00000372559.1:c.785C>T p.Thr262Ile p.T262I ENST00000372559 NM_001287046.1 262 aCc/aTc 0 +SH3KBP1 UCSF GRCh37 X 19564131 19564131 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 64 124 0 ENST00000397821.3:c.1532G>A p.Ser511Asn p.S511N ENST00000397821 NM_031892.2 511 aGt/aAt 0 +SH3KBP1 UCSF GRCh37 X 19555892 19555892 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 77 151 0 ENST00000397821.3:c.1899G>A p.Glu633= p.E633= ENST00000397821 NM_031892.2 633 gaG/gaA 0 +SH3PXD2B UCSF GRCh37 5 171849445 171849445 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 19 41 0 ENST00000311601.5:c.131G>A p.Arg44His p.R44H ENST00000311601 NM_001017995.2 44 cGc/cAc 0 +SH3RF3 UCSF GRCh37 2 109964222 109964222 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 48 108 0 ENST00000309415.6:c.666C>T p.Val222= p.V222= ENST00000309415 NM_001099289.1 222 gtC/gtT 0 +SH3TC2 UCSF GRCh37 5 148406208 148406208 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 63 197 0 ENST00000515425.1:c.2980C>T p.Leu994Phe p.L994F ENST00000515425 NM_024577.3 994 Ctc/Ttc 0 +SHB UCSF GRCh37 9 38068081 38068081 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 9 10 0 ENST00000377707.3:c.562G>A p.Val188Met p.V188M ENST00000377707 NM_003028.2 188 Gtg/Atg 0 +SHC1 UCSF GRCh37 1 154942858 154942858 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 29 66 0 ENST00000368445.5:c.145C>T p.Leu49= p.L49= ENST00000368445 NM_183001.4 49 Ctg/Ttg 0 +SHCBP1L UCSF GRCh37 1 182908644 182908644 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 30 77 0 ENST00000367547.3:c.815G>A p.Ser272Asn p.S272N ENST00000367547 NM_030933.2 272 aGt/aAt 0 +SHROOM4 UCSF GRCh37 X 50377013 50377013 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 41 98 0 ENST00000289292.7:c.2060C>T p.Pro687Leu p.P687L ENST00000289292 687 cCt/cTt 0 +SIDT1 UCSF GRCh37 3 113251941 113251941 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 7 17 0 ENST00000264852.4:c.73C>T p.Pro25Ser p.P25S ENST00000264852 NM_017699.2 25 Ccg/Tcg 0 +SIGLEC1 UCSF GRCh37 20 3672566 3672566 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 38 92 0 ENST00000344754.4:c.4314G>A p.Gly1438= p.G1438= ENST00000344754 NM_023068.3 1438 ggG/ggA 0 +SIGLEC8 UCSF GRCh37 19 51961292 51961292 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 116 229 0 ENST00000321424.3:c.350G>A p.Arg117Lys p.R117K ENST00000321424 NM_014442.2 117 aGg/aAg 0 +SIGLEC8 UCSF GRCh37 19 51960915 51960915 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 46 126 0 ENST00000321424.3:c.533C>T p.Pro178Leu p.P178L ENST00000321424 NM_014442.2 178 cCc/cTc 0 +SIN3A UCSF GRCh37 15 75664459 75664459 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 52 133 0 ENST00000360439.4:c.3683C>T p.Ala1228Val p.A1228V ENST00000360439 NM_001145357.1 1228 gCa/gTa 0 +SIPA1 UCSF GRCh37 11 65408730 65408730 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 56 106 0 ENST00000394224.3:c.338C>T p.Pro113Leu p.P113L ENST00000394224 NM_153253.29 113 cCt/cTt 0 +SIPA1L2 UCSF GRCh37 1 232577605 232577605 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 18 33 0 ENST00000262861.4:c.3447C>T p.Ser1149= p.S1149= ENST00000262861 NM_020808.3 1149 tcC/tcT 0 +SIRPA UCSF GRCh37 20 1902070 1902070 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 67 143 0 ENST00000356025.3:c.466C>T p.Pro156Ser p.P156S ENST00000356025 NM_080792.2 156 Cct/Tct 0 +SIT1 UCSF GRCh37 9 35650018 35650018 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 19 35 0 ENST00000259608.3:c.418C>T p.Pro140Ser p.P140S ENST00000259608 NM_014450.2 140 Ccc/Tcc 0 +SIX1 UCSF GRCh37 14 61113237 61113237 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 42 88 0 ENST00000247182.6:c.619G>A p.Glu207Lys p.E207K ENST00000247182 NM_005982.3 207 Gaa/Aaa 0 +SKIL UCSF GRCh37 3 170078528 170078528 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 118 214 0 ENST00000259119.4:c.409C>T p.Pro137Ser p.P137S ENST00000259119 137 Cct/Tct 0 +SKIV2L UCSF GRCh37 6 31935054 31935054 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 70 106 0 ENST00000375394.2:c.2483G>A p.Arg828His p.R828H ENST00000375394 NM_006929.4 828 cGc/cAc 0 +SKIV2L UCSF GRCh37 6 31928006 31928006 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 141 135 226 0 ENST00000375394.2:c.246G>A p.Gln82= p.Q82= ENST00000375394 NM_006929.4 82 caG/caA 0 +SKIV2L2 UCSF GRCh37 5 54637533 54637533 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 44 140 0 ENST00000230640.5:c.715G>A p.Gly239Ser p.G239S ENST00000230640 NM_015360.4 239 Ggt/Agt 0 +SLC10A1 UCSF GRCh37 14 70263533 70263533 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 29 65 0 ENST00000216540.4:c.340G>A p.Gly114Arg p.G114R ENST00000216540 NM_003049.3 114 Ggg/Agg 0 +SLC12A1 UCSF GRCh37 15 48548020 48548020 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 52 127 0 ENST00000380993.3:c.1955G>A p.Gly652Asp p.G652D ENST00000380993 NM_000338.2 652 gGc/gAc 0 +SLC12A1 UCSF GRCh37 15 48559879 48559879 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 93 222 0 ENST00000380993.3:c.2276G>A p.Gly759Asp p.G759D ENST00000380993 NM_000338.2 759 gGt/gAt 0 +SLC12A5 UCSF GRCh37 20 44683654 44683654 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 28 58 0 ENST00000454036.2:c.2848G>A p.Glu950Lys p.E950K ENST00000454036 NM_001134771.1 950 Gag/Aag 0 +SLC12A8 UCSF GRCh37 3 124826835 124826835 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 48 108 0 ENST00000393469.4:c.1195G>A p.Asp399Asn p.D399N ENST00000393469 NM_001195483.1 399 Gac/Aac 0 +SLC17A8 UCSF GRCh37 12 100813607 100813607 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 54 132 0 ENST00000323346.5:c.1440G>A p.Trp480Ter p.W480* ENST00000323346 NM_001145288.1 480 tgG/tgA 0 +SLC17A9 UCSF GRCh37 20 61593991 61593991 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 43 70 0 ENST00000370351.4:c.513G>A p.Gly171= p.G171= ENST00000370351 NM_022082.3 171 ggG/ggA 0 +SLC18A3 UCSF GRCh37 10 50818864 50818864 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 7 17 0 ENST00000374115.3:c.78G>A p.Gln26= p.Q26= ENST00000374115 NM_003055.2 26 caG/caA 0 +SLC20A1 UCSF GRCh37 2 113417272 113417272 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 99 197 0 ENST00000272542.3:c.1540C>T p.Leu514Phe p.L514F ENST00000272542 NM_005415.4 514 Ctc/Ttc 0 +SLC22A12 UCSF GRCh37 11 64359268 64359268 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 39 57 0 ENST00000377574.1:c.240C>T p.Gly80= p.G80= ENST00000377574 NM_144585.3 80 ggC/ggT 0 +SLC22A15 UCSF GRCh37 1 116569552 116569552 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 119 116 252 0 ENST00000369503.4:c.637C>T p.Gln213Ter p.Q213* ENST00000369503 NM_018420.2 213 Caa/Taa 0 +SLC22A25 UCSF GRCh37 11 62996921 62996921 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 79 163 0 ENST00000306494.6:c.204C>T p.Ser68= p.S68= ENST00000306494 NM_199352.3 68 agC/agT 0 +SLC22A7 UCSF GRCh37 6 43266456 43266456 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 44 96 0 ENST00000372585.5:c.360C>T p.Asp120= p.D120= ENST00000372585 NM_153320.2 120 gaC/gaT 0 +SLC22A8 UCSF GRCh37 11 62762197 62762197 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 43 106 0 ENST00000336232.2:c.1033G>A p.Ala345Thr p.A345T ENST00000336232 NM_001184736.1 345 Gct/Act 0 +SLC25A2 UCSF GRCh37 5 140682715 140682715 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 82 151 0 ENST00000239451.4:c.718C>T p.Leu240Phe p.L240F ENST00000239451 NM_031947.2 240 Ctt/Ttt 0 +SLC25A23 UCSF GRCh37 19 6454397 6454397 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 83 163 0 ENST00000301454.4:c.732C>T p.Gly244= p.G244= ENST00000301454 NM_024103.2 244 ggC/ggT 0 +SLC25A47 UCSF GRCh37 14 100793657 100793657 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 48 73 0 ENST00000361529.3:c.277C>T p.Pro93Ser p.P93S ENST00000361529 NM_207117.2 93 Ccc/Tcc 0 +SLC25A47 UCSF GRCh37 14 100792129 100792129 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 12 30 0 ENST00000361529.3:c.33C>T p.Val11= p.V11= ENST00000361529 NM_207117.2 11 gtC/gtT 0 +SLC26A3 UCSF GRCh37 7 107427920 107427920 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 75 204 0 ENST00000340010.5:c.770C>T p.Thr257Ile p.T257I ENST00000340010 NM_000111.2 257 aCt/aTt 0 +SLC26A7 UCSF GRCh37 8 92406050 92406050 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 246 70 188 0 ENST00000276609.3:c.1802G>A p.Ser601Asn p.S601N ENST00000276609 NM_052832.2 601 aGt/aAt 0 +SLC26A8 UCSF GRCh37 6 35945047 35945047 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 75 149 0 ENST00000355574.2:c.1107C>T p.Ser369= p.S369= ENST00000355574 NM_001193476.1 369 tcC/tcT 0 +SLC27A1 UCSF GRCh37 19 17608123 17608123 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 21 36 0 ENST00000252595.7:c.1056G>A p.Ala352= p.A352= ENST00000252595 NM_198580.1 352 gcG/gcA 0 +SLC27A6 UCSF GRCh37 5 128368798 128368798 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 33 81 0 ENST00000262462.4:c.1684-1G>A p.X562_splice ENST00000262462 0 +SLC29A1 UCSF GRCh37 6 44197742 44197742 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 28 69 0 ENST00000371708.1:c.413C>T p.Pro138Leu p.P138L ENST00000371708 138 cCc/cTc 0 +SLC2A12 UCSF GRCh37 6 134349911 134349911 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 82 167 0 ENST00000275230.5:c.1052C>T p.Ser351Phe p.S351F ENST00000275230 NM_145176.2 351 tCc/tTc 0 +SLC2A8 UCSF GRCh37 9 130167116 130167116 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 31 55 0 ENST00000373371.3:c.996C>T p.Ser332= p.S332= ENST00000373371 NM_014580.4 332 agC/agT 0 +SLC32A1 UCSF GRCh37 20 37356347 37356347 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 52 71 0 ENST00000217420.1:c.643G>A p.Val215Met p.V215M ENST00000217420 NM_080552.2 215 Gtg/Atg 0 +SLC34A1 UCSF GRCh37 5 176814997 176814997 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 24 40 0 ENST00000324417.5:c.647C>T p.Ala216Val p.A216V ENST00000324417 NM_003052.4 216 gCc/gTc 0 +SLC34A3 UCSF GRCh37 9 140130583 140130583 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 31 68 0 ENST00000361134.2:c.1515G>A p.Gly505= p.G505= ENST00000361134 NM_080877.2 505 ggG/ggA 0 +SLC36A1 UCSF GRCh37 5 150838470 150838470 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 49 118 0 ENST00000243389.3:c.117G>A p.Gln39= p.Q39= ENST00000243389 NM_078483.2 39 caG/caA 0 +SLC38A2 UCSF GRCh37 12 46756118 46756118 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 33 74 0 ENST00000256689.5:c.1371C>T p.Phe457= p.F457= ENST00000256689 NM_018976.4 457 ttC/ttT 0 +SLC39A11 UCSF GRCh37 17 70645311 70645311 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 30 61 0 ENST00000542342.2:c.789C>T p.Phe263= p.F263= ENST00000542342 NM_001159770.1 263 ttC/ttT 0 +SLC39A12 UCSF GRCh37 10 18292187 18292187 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 169 80 206 0 ENST00000377369.2:c.1847G>A p.Gly616Glu p.G616E ENST00000377369 NM_001145195.1 616 gGa/gAa 0 +SLC39A14 UCSF GRCh37 8 22277162 22277162 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 86 153 0 ENST00000289952.5:c.1430C>T p.Thr477Ile p.T477I ENST00000289952 NM_001135153.1 477 aCc/aTc 0 +SLC39A4 UCSF GRCh37 8 145641314 145641314 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 9 20 0 ENST00000301305.3:c.354C>T p.Leu118= p.L118= ENST00000301305 NM_130849.3 118 ctC/ctT 0 +SLC41A3 UCSF GRCh37 3 125786943 125786943 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 57 125 0 ENST00000315891.6:c.120C>T p.Leu40= p.L40= ENST00000315891 NM_017836.3 40 ctC/ctT 0 +SLC44A1 UCSF GRCh37 9 108061522 108061522 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 36 121 0 ENST00000374720.3:c.58C>T p.Pro20Ser p.P20S ENST00000374720 NM_080546.3 20 Ccg/Tcg 0 +SLC44A2 UCSF GRCh37 19 10742341 10742341 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 37 81 0 ENST00000335757.5:c.542G>A p.Gly181Asp p.G181D ENST00000335757 181 gGt/gAt 0 +SLC45A2 UCSF GRCh37 5 33947310 33947310 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 113 109 219 0 ENST00000296589.4:c.1326C>T p.Pro442= p.P442= ENST00000296589 NM_016180.3 442 ccC/ccT 0 +SLC4A10 UCSF GRCh37 2 162757488 162757488 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 56 167 0 ENST00000446997.1:c.1409G>A p.Gly470Glu p.G470E ENST00000446997 NM_001178015.1 470 gGa/gAa 0 +SLC4A2 UCSF GRCh37 7 150772436 150772436 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 68 81 0 ENST00000413384.2:c.3142C>T p.Leu1048Phe p.L1048F ENST00000413384 NM_003040.3 1048 Ctc/Ttc 0 +SLC4A3 UCSF GRCh37 2 220504259 220504259 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 44 83 0 ENST00000317151.3:c.3079G>A p.Asp1027Asn p.D1027N ENST00000317151 1027 Gac/Aac 0 +SLC4A5 UCSF GRCh37 2 74492354 74492354 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 70 136 0 ENST00000346834.4:c.439G>A p.Glu147Lys p.E147K ENST00000346834 147 Gaa/Aaa 0 +SLC4A9 UCSF GRCh37 5 139744000 139744000 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 52 97 0 ENST00000507527.1:c.1513G>A p.Ala505Thr p.A505T ENST00000507527 505 Gct/Act 0 +SLC5A10 UCSF GRCh37 17 18918429 18918429 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 24 36 0 ENST00000395645.3:c.1158C>T p.Asn386= p.N386= ENST00000395645 NM_001042450.2 386 aaC/aaT 0 +SLC5A2 UCSF GRCh37 16 31499971 31499971 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 10 17 0 ENST00000330498.3:c.1158G>A p.Met386Ile p.M386I ENST00000330498 NM_003041.3 386 atG/atA 0 +SLC5A5 UCSF GRCh37 19 17994721 17994721 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 9 9 0 ENST00000222248.3:c.1392G>A p.Thr464= p.T464= ENST00000222248 NM_000453.2 464 acG/acA 0 +SLC5A8 UCSF GRCh37 12 101581270 101581270 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 52 139 0 ENST00000536262.2:c.857G>A p.Gly286Glu p.G286E ENST00000536262 NM_145913.3 286 gGa/gAa 0 +SLC6A17 UCSF GRCh37 1 110717545 110717545 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 29 69 0 ENST00000331565.4:c.716G>A p.Gly239Glu p.G239E ENST00000331565 NM_001010898.2 239 gGg/gAg 0 +SLC7A14 UCSF GRCh37 3 170219032 170219032 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 57 96 0 ENST00000231706.5:c.407G>A p.Gly136Asp p.G136D ENST00000231706 NM_020949.2 136 gGc/gAc 0 +SLC7A5 UCSF GRCh37 16 87873374 87873374 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 35 64 0 ENST00000261622.4:c.873G>A p.Leu291= p.L291= ENST00000261622 NM_003486.5 291 ctG/ctA 0 +SLC8A2 UCSF GRCh37 19 47935628 47935628 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 54 86 0 ENST00000236877.6:c.2185C>T p.Leu729= p.L729= ENST00000236877 NM_015063.2 729 Ctg/Ttg 0 +SLCO1B1 UCSF GRCh37 12 21377716 21377716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 75 157 0 ENST00000256958.2:c.1808C>T p.Ser603Phe p.S603F ENST00000256958 NM_006446.4 603 tCc/tTc 0 +SLCO1B7 UCSF GRCh37 12 21175906 21175906 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 125 101 211 0 ENST00000421593.2:c.463G>A p.Glu155Lys p.E155K ENST00000421593 NM_001009562.4 155 Gaa/Aaa 0 +SLCO1B7 UCSF GRCh37 12 21176207 21176207 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 62 190 0 ENST00000421593.2:c.572G>A p.Gly191Glu p.G191E ENST00000421593 NM_001009562.4 191 gGa/gAa 0 +SLCO3A1 UCSF GRCh37 15 92663699 92663699 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 93 147 0 ENST00000318445.6:c.1014C>T p.Ile338= p.I338= ENST00000318445 NM_013272.3 338 atC/atT 0 +SLFN11 UCSF GRCh37 17 33689878 33689878 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 93 171 0 ENST00000308377.4:c.949G>A p.Val317Ile p.V317I ENST00000308377 NM_152270.3 317 Gta/Ata 0 +SLFN5 UCSF GRCh37 17 33592592 33592592 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 100 157 1 ENST00000299977.4:c.2361G>A p.Pro787= p.P787= ENST00000299977 NM_144975.3 787 ccG/ccA 0 +SLIT2 UCSF GRCh37 4 20618640 20618640 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 53 128 0 ENST00000504154.1:c.3955G>A p.Asp1319Asn p.D1319N ENST00000504154 NM_004787.1 1319 Gac/Aac 0 +SLIT3 UCSF GRCh37 5 168233465 168233465 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 50 106 1 ENST00000519560.1:c.921G>A p.Glu307= p.E307= ENST00000519560 NM_003062.3 307 gaG/gaA 0 +SLITRK3 UCSF GRCh37 3 164907600 164907600 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 92 252 0 ENST00000241274.3:c.1019G>A p.Arg340Gln p.R340Q ENST00000241274 NM_014926.2 340 cGa/cAa 0 +SLITRK3 UCSF GRCh37 3 164907019 164907019 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 65 140 0 ENST00000241274.3:c.1600C>T p.Leu534= p.L534= ENST00000241274 NM_014926.2 534 Ctg/Ttg 0 +SLK UCSF GRCh37 10 105727625 105727625 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 73 142 0 ENST00000369755.3:c.122G>A p.Gly41Asp p.G41D ENST00000369755 NM_014720.2 41 gGc/gAc 0 +SLX4 UCSF GRCh37 16 3651005 3651005 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 40 97 0 ENST00000294008.3:c.1138G>A p.Gly380Ser p.G380S ENST00000294008 NM_032444.2 380 Ggt/Agt 0 +SMAD4 UCSF GRCh37 18 48604826 48604826 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 82 58 147 0 ENST00000342988.3:c.1648C>T p.Pro550Ser p.P550S ENST00000342988 NM_005359.5 550 Cct/Tct 0 +SMARCA2 UCSF GRCh37 9 2123736 2123736 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 26 52 0 ENST00000349721.2:c.3780G>A p.Arg1260= p.R1260= ENST00000349721 NM_003070.3 1260 cgG/cgA 0 +SMARCC1 UCSF GRCh37 3 47663775 47663775 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 73 220 0 ENST00000254480.5:c.2703G>A p.Glu901= p.E901= ENST00000254480 NM_003074.3 901 gaG/gaA 0 +SMCR8 UCSF GRCh37 17 18220963 18220963 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 105 154 0 ENST00000406438.3:c.1860G>A p.Arg620= p.R620= ENST00000406438 NM_144775.2 620 agG/agA 0 +SMG6 UCSF GRCh37 17 2200618 2200618 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 44 121 0 ENST00000263073.6:c.2070G>A p.Gln690= p.Q690= ENST00000263073 NM_017575.4 690 caG/caA 0 +SMG8 UCSF GRCh37 17 57290819 57290819 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 114 225 0 ENST00000300917.5:c.2635G>A p.Ala879Thr p.A879T ENST00000300917 NM_018149.6 879 Gct/Act 0 +SMG9 UCSF GRCh37 19 44251629 44251629 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 46 86 0 ENST00000270066.6:c.553G>A p.Asp185Asn p.D185N ENST00000270066 NM_019108.2 185 Gat/Aat 0 +SMG9 UCSF GRCh37 19 44251950 44251950 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 19 41 0 ENST00000270066.6:c.325G>A p.Gly109Arg p.G109R ENST00000270066 NM_019108.2 109 Ggg/Agg 0 +SMOX UCSF GRCh37 20 4164244 4164244 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 32 93 0 ENST00000305958.4:c.1473G>A p.Gly491= p.G491= ENST00000305958 NM_175839.2 491 ggG/ggA 0 +SMPD3 UCSF GRCh37 16 68405569 68405569 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 23 37 0 ENST00000219334.5:c.516C>T p.Asp172= p.D172= ENST00000219334 NM_018667.3 172 gaC/gaT 0 +SMPD4 UCSF GRCh37 2 130911459 130911459 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 28 102 0 ENST00000409031.1:c.1826C>T p.Ser609Phe p.S609F ENST00000409031 NM_017951.4 609 tCc/tTc 0 +SMYD4 UCSF GRCh37 17 1690757 1690757 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 11 18 0 ENST00000305513.7:c.1679C>T p.Ser560Leu p.S560L ENST00000305513 NM_052928.2 560 tCa/tTa 0 +SNAP47 UCSF GRCh37 1 227935765 227935765 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 38 90 0 ENST00000315781.5:c.463G>A p.Ala155Thr p.A155T ENST00000315781 155 Gca/Aca 0 +SNAP91 UCSF GRCh37 6 84302924 84302924 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 82 163 0 ENST00000369694.2:c.1751C>T p.Pro584Leu p.P584L ENST00000369694 NM_001242792.1 584 cCt/cTt 0 +SNAPC4 UCSF GRCh37 9 139272750 139272750 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 15 20 0 ENST00000298532.2:c.3529G>A p.Glu1177Lys p.E1177K ENST00000298532 NM_003086.2 1177 Gag/Aag 0 +SNAPC4 UCSF GRCh37 9 139273417 139273417 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 10 23 0 ENST00000298532.2:c.2862G>A p.Gly954= p.G954= ENST00000298532 NM_003086.2 954 ggG/ggA 0 +SND1 UCSF GRCh37 7 127338952 127338952 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 37 114 0 ENST00000354725.3:c.373G>A p.Glu125Lys p.E125K ENST00000354725 NM_014390.2 125 Gaa/Aaa 0 +SNRNP70 UCSF GRCh37 19 49611115 49611115 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 9 14 0 ENST00000598441.1:c.729G>A p.Glu243= p.E243= ENST00000598441 243 gaG/gaA 0 +SNTB1 UCSF GRCh37 8 121823749 121823749 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 25 29 0 ENST00000395601.3:c.335G>A p.Gly112Asp p.G112D ENST00000395601 NM_021021.3 112 gGc/gAc 0 +SNX10 UCSF GRCh37 7 26411640 26411641 + frameshift_variant Frame_Shift_Del DEL TA TA - NOVEL P10_Rec Untested WXS Illumina HiSeq 56 0 ENST00000338523.4:c.512_513del p.Tyr171Ter p.Y171* ENST00000338523 NM_013322.2 171 TAt/t 0 +SNX14 UCSF GRCh37 6 86217778 86217778 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 34 60 0 ENST00000314673.3:c.2654-1G>A p.X885_splice ENST00000314673 NM_153816.3 0 +SNX25 UCSF GRCh37 4 186272737 186272737 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 57 135 0 ENST00000264694.8:c.1948C>T p.Pro650Ser p.P650S ENST00000264694 NM_031953.2 650 Cct/Tct 0 +SNX3 UCSF GRCh37 6 108582003 108582003 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 25 56 0 ENST00000230085.8:c.123C>T p.Val41= p.V41= ENST00000230085 NM_003795.4 41 gtC/gtT 0 +SNX30 UCSF GRCh37 9 115598667 115598667 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 199 96 159 0 ENST00000374232.3:c.792G>A p.Gln264= p.Q264= ENST00000374232 NM_001012994.1 264 caG/caA 0 +SOCS4 UCSF GRCh37 14 55510165 55510165 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 66 146 0 ENST00000339298.2:c.406C>T p.Pro136Ser p.P136S ENST00000339298 136 Cct/Tct 0 +SOCS7 UCSF GRCh37 17 36552203 36552203 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 44 92 0 ENST00000577233.1:c.1728G>A p.Glu576= p.E576= ENST00000577233 NM_014598.2 576 gaG/gaA 0 +SON UCSF GRCh37 21 34923735 34923735 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 104 199 0 ENST00000356577.4:c.2198C>T p.Ser733Phe p.S733F ENST00000356577 NM_138927.2 733 tCc/tTc 0 +SON UCSF GRCh37 21 34927520 34927520 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 50 78 0 ENST00000356577.4:c.5983C>T p.Pro1995Ser p.P1995S ENST00000356577 NM_138927.2 1995 Cca/Tca 0 +SORBS1 UCSF GRCh37 10 97131152 97131152 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 59 139 0 ENST00000361941.3:c.1836G>A p.Gln612= p.Q612= ENST00000361941 NM_001034954.1 612 caG/caA 0 +SORBS2 UCSF GRCh37 4 186508806 186508806 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 12 42 0 ENST00000284776.7:c.3278C>T p.Pro1093Leu p.P1093L ENST00000284776 NM_021069.4 1093 cCc/cTc 0 +SOX13 UCSF GRCh37 1 204095146 204095146 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 56 96 0 ENST00000367204.1:c.1753G>A p.Glu585Lys p.E585K ENST00000367204 NM_005686.2 585 Gag/Aag 0 +SOX15 UCSF GRCh37 17 7492604 7492604 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 13 32 0 ENST00000250055.2:c.391C>T p.Pro131Ser p.P131S ENST00000250055 NM_006942.1 131 Cct/Tct 0 +SOX2 UCSF GRCh37 3 181431096 181431096 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 12 22 0 ENST00000325404.1:c.948C>T p.His316= p.H316= ENST00000325404 NM_003106.3 316 caC/caT 0 +SOX6 UCSF GRCh37 11 16362714 16362714 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 86 143 0 ENST00000528429.1:c.81G>A p.Arg27= p.R27= ENST00000528429 NM_001145819.1 27 agG/agA 0 +SOX7 UCSF GRCh37 8 10587927 10587927 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 11 24 0 ENST00000304501.1:c.17G>A p.Gly6Glu p.G6E ENST00000304501 NM_031439.3 6 gGa/gAa 0 +SP7 UCSF GRCh37 12 53722435 53722435 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 38 101 0 ENST00000303846.3:c.791G>A p.Gly264Glu p.G264E ENST00000303846 NM_152860.1 264 gGg/gAg 0 +SPAG4 UCSF GRCh37 20 34207233 34207233 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 38 101 0 ENST00000374273.3:c.909+1G>A p.X303_splice ENST00000374273 NM_003116.1 0 +SPAG5 UCSF GRCh37 17 26919902 26919902 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 128 226 0 ENST00000321765.5:c.360C>T p.Asp120= p.D120= ENST00000321765 NM_006461.3 120 gaC/gaT 0 +SPAG6 UCSF GRCh37 10 22653922 22653922 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 47 110 0 ENST00000376624.3:c.262C>T p.Leu88Phe p.L88F ENST00000376624 NM_012443.3 88 Ctt/Ttt 0 +SPATA18 UCSF GRCh37 4 52946055 52946055 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 90 210 0 ENST00000295213.4:c.1325G>A p.Gly442Glu p.G442E ENST00000295213 NM_145263.2 442 gGa/gAa 0 +SPATS2 UCSF GRCh37 12 49912891 49912891 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 35 69 0 ENST00000321898.6:c.934C>T p.Leu312Phe p.L312F ENST00000321898 312 Ctt/Ttt 0 +SPDYA UCSF GRCh37 2 29039088 29039088 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 61 125 0 ENST00000334056.5:c.208G>A p.Asp70Asn p.D70N ENST00000334056 NM_182756.3 70 Gat/Aat 0 +SPEF1 UCSF GRCh37 20 3759405 3759405 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 38 63 0 ENST00000379756.3:c.467G>A p.Gly156Glu p.G156E ENST00000379756 NM_015417.4 156 gGg/gAg 0 +SPEN UCSF GRCh37 1 16262589 16262589 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 44 82 0 ENST00000375759.3:c.9854C>T p.Pro3285Leu p.P3285L ENST00000375759 NM_015001.2 3285 cCt/cTt 0 +SPEN UCSF GRCh37 1 16254682 16254682 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 90 186 0 ENST00000375759.3:c.1947C>T p.Asp649= p.D649= ENST00000375759 NM_015001.2 649 gaC/gaT 0 +SPG11 UCSF GRCh37 15 44865887 44865887 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 46 106 0 ENST00000261866.7:c.6063G>A p.Arg2021= p.R2021= ENST00000261866 NM_025137.3 2021 cgG/cgA 0 +SPON1 UCSF GRCh37 11 14284274 14284274 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 107 215 0 ENST00000310358.7:n.2548C>T *850* ENST00000310358 0 +SPTBN5 UCSF GRCh37 15 42145961 42145961 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 23 38 0 ENST00000320955.6:c.9799G>A p.Glu3267Lys p.E3267K ENST00000320955 NM_016642.3 3267 Gag/Aag 0 +SPTBN5 UCSF GRCh37 15 42143262 42143262 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 39 76 0 ENST00000320955.6:c.10830C>T p.Ser3610= p.S3610= ENST00000320955 NM_016642.3 3610 tcC/tcT 0 +SPTLC2 UCSF GRCh37 14 78028832 78028832 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 43 88 0 ENST00000216484.2:c.757G>A p.Gly253Ser p.G253S ENST00000216484 NM_004863.3 253 Ggt/Agt 0 +SQLE UCSF GRCh37 8 126034070 126034070 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 278 86 210 0 ENST00000265896.5:c.1608G>A p.Lys536= p.K536= ENST00000265896 NM_003129.3 536 aaG/aaA 0 +SRA1 UCSF GRCh37 5 139931739 139931739 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0047 P10_Rec Untested WXS Illumina HiSeq 36 21 48 0 ENST00000336283.6:c.218C>T p.Pro73Leu p.P73L ENST00000336283 NM_001035235.3 73 cCc/cTc 0 +SRCAP UCSF GRCh37 16 30749234 30749234 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 42 111 0 ENST00000262518.4:c.7873C>T p.Pro2625Ser p.P2625S ENST00000262518 NM_006662.2 2625 Cca/Tca 0 +SRCAP UCSF GRCh37 16 30749404 30749404 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 47 100 0 ENST00000262518.4:c.8043G>A p.Lys2681= p.K2681= ENST00000262518 NM_006662.2 2681 aaG/aaA 0 +SREBF1 UCSF GRCh37 17 17722445 17722445 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 52 107 0 ENST00000261646.5:c.950C>T p.Ser317Phe p.S317F ENST00000261646 NM_004176.4 317 tCt/tTt 0 +SREBF1 UCSF GRCh37 17 17719820 17719820 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 9 18 0 ENST00000261646.5:c.1998C>T p.Ala666= p.A666= ENST00000261646 NM_004176.4 666 gcC/gcT 0 +SRP68 UCSF GRCh37 17 74053530 74053530 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 55 147 0 ENST00000307877.2:c.932G>A p.Arg311His p.R311H ENST00000307877 NM_014230.3 311 cGc/cAc 0 +SRP72 UCSF GRCh37 4 57335892 57335892 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 64 150 0 ENST00000342756.5:c.183C>T p.Phe61= p.F61= ENST00000342756 NM_006947.3 61 ttC/ttT 0 +SRRT UCSF GRCh37 7 100484763 100484763 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 84 138 0 ENST00000347433.4:c.1917C>T p.Arg639= p.R639= ENST00000347433 639 cgC/cgT 0 +SSBP2 UCSF GRCh37 5 80733256 80733256 + missense_variant Missense_Mutation SNP A A C NOVEL P10_Rec Untested WXS Illumina HiSeq 82 79 164 0 ENST00000320672.4:c.950T>G p.Ile317Ser p.I317S ENST00000320672 NM_001256732.1 317 aTt/aGt 0 +SSBP2 UCSF GRCh37 5 80809501 80809501 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 79 158 0 ENST00000320672.4:c.318C>T p.Asn106= p.N106= ENST00000320672 NM_001256732.1 106 aaC/aaT 0 +SSBP3 UCSF GRCh37 1 54704825 54704825 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 88 156 0 ENST00000371320.3:c.904C>T p.Pro302Ser p.P302S ENST00000371320 NM_145716.3 302 Ccg/Tcg 0 +SSH3 UCSF GRCh37 11 67075382 67075382 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 37 59 0 ENST00000308127.4:c.857G>A p.Ser286Asn p.S286N ENST00000308127 NM_017857.3 286 aGt/aAt 0 +SSH3 UCSF GRCh37 11 67075717 67075717 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 42 87 0 ENST00000308127.4:c.958C>T p.Leu320= p.L320= ENST00000308127 NM_017857.3 320 Ctg/Ttg 0 +SSPO UCSF GRCh37 7 149494363 149494363 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 54 126 0 ENST00000378016.2:n.6834C>T *2278* ENST00000378016 0 +SSPO UCSF GRCh37 7 149521558 149521558 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 27 47 0 ENST00000378016.2:n.13637C>T *4546* ENST00000378016 0 +SSPO UCSF GRCh37 7 149517757 149517757 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 8 16 0 ENST00000378016.2:n.12194G>A *4065* ENST00000378016 0 +SSPO UCSF GRCh37 7 149496924 149496924 + splice_region_variant,non_coding_transcript_exon_variant Splice_Region SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 38 36 70 1 ENST00000378016.2:n.6964A>G p.X2322_splice ENST00000378016 0 +SSPO UCSF GRCh37 7 149490472 149490472 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 12 25 0 ENST00000378016.2:n.5948G>A *1983* ENST00000378016 0 +ST7L UCSF GRCh37 1 113124626 113124626 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 104 228 0 ENST00000358039.4:c.1057G>A p.Ala353Thr p.A353T ENST00000358039 NM_138727.3 353 Gca/Aca 0 +STAB1 UCSF GRCh37 3 52539369 52539369 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 22 40 0 ENST00000321725.6:c.1553C>T p.Ala518Val p.A518V ENST00000321725 NM_015136.2 518 gCc/gTc 0 +STAB2 UCSF GRCh37 12 104136309 104136309 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 82 211 0 ENST00000388887.2:c.6008G>A p.Gly2003Glu p.G2003E ENST00000388887 NM_017564.9 2003 gGg/gAg 0 +STAB2 UCSF GRCh37 12 104134509 104134509 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 55 133 0 ENST00000388887.2:c.5856G>A p.Lys1952= p.K1952= ENST00000388887 NM_017564.9 1952 aaG/aaA 0 +STAB2 UCSF GRCh37 12 104144413 104144413 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 57 115 0 ENST00000388887.2:c.6495G>A p.Glu2165= p.E2165= ENST00000388887 NM_017564.9 2165 gaG/gaA 0 +STAG2 UCSF GRCh37 X 123197828 123197828 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 57 51 134 0 ENST00000371144.3:c.1952A>G p.Asp651Gly p.D651G ENST00000371144 NM_001042751.1 651 gAt/gGt 0 +STAG2 UCSF GRCh37 X 123197850 123197850 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 64 60 128 0 ENST00000371144.3:c.1974A>G p.Ile658Met p.I658M ENST00000371144 NM_001042751.1 658 atA/atG 0 +STAR UCSF GRCh37 8 38001867 38001867 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 9 26 0 ENST00000276449.4:c.782C>T p.Ser261Phe p.S261F ENST00000276449 NM_000349.2 261 tCc/tTc 0 +STAT3 UCSF GRCh37 17 40481593 40481593 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 135 109 190 0 ENST00000264657.5:c.1212C>T p.Leu404= p.L404= ENST00000264657 NM_139276.2 404 ctC/ctT 0 +STK10 UCSF GRCh37 5 171481694 171481694 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 68 105 0 ENST00000176763.5:c.2531C>T p.Ser844Phe p.S844F ENST00000176763 NM_005990.3 844 tCc/tTc 0 +STK32A UCSF GRCh37 5 146752788 146752788 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 96 201 0 ENST00000397936.3:c.834C>T p.Phe278= p.F278= ENST00000397936 NM_001112724.1 278 ttC/ttT 0 +STOX1 UCSF GRCh37 10 70646337 70646337 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 57 126 0 ENST00000298596.6:c.2785C>T p.His929Tyr p.H929Y ENST00000298596 NM_152709.4 929 Cac/Tac 0 +STXBP2 UCSF GRCh37 19 7707331 7707331 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 55 118 0 ENST00000221283.5:c.811C>T p.Leu271= p.L271= ENST00000221283 NM_006949.3 271 Ctg/Ttg 0 +STXBP5 UCSF GRCh37 6 147525712 147525712 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 13 33 0 ENST00000321680.6:c.44C>T p.Ala15Val p.A15V ENST00000321680 NM_001127715.2 15 gCc/gTc 0 +STXBP5L UCSF GRCh37 3 121132107 121132107 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 73 133 0 ENST00000273666.6:c.3123C>T p.Tyr1041= p.Y1041= ENST00000273666 NM_014980.2 1041 taC/taT 0 +STYK1 UCSF GRCh37 12 10772850 10772850 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 104 234 0 ENST00000075503.3:c.1162G>A p.Asp388Asn p.D388N ENST00000075503 NM_018423.2 388 Gat/Aat 0 +SUDS3 UCSF GRCh37 12 118823930 118823930 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 68 159 0 ENST00000543473.1:c.280G>A p.Glu94Lys p.E94K ENST00000543473 NM_022491.2 94 Gaa/Aaa 0 +SULT1A2 UCSF GRCh37 16 28604784 28604784 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 67 150 0 ENST00000335715.4:c.478G>A p.Glu160Lys p.E160K ENST00000335715 NM_001054.3 160 Gag/Aag 0 +SUN5 UCSF GRCh37 20 31571649 31571649 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 74 152 0 ENST00000356173.3:c.1091C>T p.Ala364Val p.A364V ENST00000356173 NM_080675.3 364 gCc/gTc 0 +SUSD1 UCSF GRCh37 9 114875083 114875083 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 107 38 137 0 ENST00000374270.3:c.952T>C p.Ser318Pro p.S318P ENST00000374270 NM_022486.3 318 Tca/Cca 0 +SV2A UCSF GRCh37 1 149878210 149878210 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 12 81 0 ENST00000369146.3:c.1877G>A p.Arg626Lys p.R626K ENST00000369146 NM_014849.4 626 aGa/aAa 0 +SVEP1 UCSF GRCh37 9 113238568 113238568 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 199 93 172 0 ENST00000374469.1:c.2446G>A p.Asp816Asn p.D816N ENST00000374469 816 Gac/Aac 0 +SVEP1 UCSF GRCh37 9 113169029 113169029 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 249 113 278 0 ENST00000374469.1:c.8782C>T p.Pro2928Ser p.P2928S ENST00000374469 2928 Cct/Tct 0 +SYCP1 UCSF GRCh37 1 115399279 115399279 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 43 100 0 ENST00000369518.1:c.193+1G>A p.X65_splice ENST00000369518 0 +SYK UCSF GRCh37 9 93607751 93607751 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 52 140 0 ENST00000375746.1:c.453G>A p.Lys151= p.K151= ENST00000375746 NM_001174167.1 151 aaG/aaA 0 +SYNE1 UCSF GRCh37 6 152674744 152674744 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 52 130 0 ENST00000367255.5:c.11062G>A p.Ala3688Thr p.A3688T ENST00000367255 NM_182961.3 3688 Gcc/Acc 0 +SYNE1 UCSF GRCh37 6 152605293 152605293 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 45 88 0 ENST00000367255.5:c.18027G>A p.Glu6009= p.E6009= ENST00000367255 NM_182961.3 6009 gaG/gaA 0 +SYNE1 UCSF GRCh37 6 152694193 152694193 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 141 140 228 0 ENST00000367255.5:c.9486C>T p.His3162= p.H3162= ENST00000367255 NM_182961.3 3162 caC/caT 0 +SYNE2 UCSF GRCh37 14 64460688 64460688 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 75 124 0 ENST00000344113.4:c.2781+1G>A p.X927_splice ENST00000344113 NM_015180.4 0 +SYNJ1 UCSF GRCh37 21 34060638 34060638 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 22 65 0 ENST00000433931.2:c.946G>A p.Ala316Thr p.A316T ENST00000433931 NM_003895.3 316 Gcc/Acc 0 +SYNPO UCSF GRCh37 5 149997948 149997948 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 9 25 0 ENST00000394243.1:c.19C>T p.Pro7Ser p.P7S ENST00000394243 NM_001166208.1 7 Cca/Tca 0 +SYNPO2 UCSF GRCh37 4 119952515 119952515 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 86 155 0 ENST00000429713.2:c.2585C>T p.Ser862Phe p.S862F ENST00000429713 NM_001128933.1 862 tCc/tTc 0 +SYNPO2L UCSF GRCh37 10 75407132 75407132 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 66 111 0 ENST00000394810.2:c.2278G>A p.Glu760Lys p.E760K ENST00000394810 NM_001114133.1 760 Gag/Aag 0 +SYNRG UCSF GRCh37 17 35913924 35913924 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 84 173 0 ENST00000339208.6:c.1901C>T p.Ser634Leu p.S634L ENST00000339208 NM_001163544.1 634 tCa/tTa 0 +SYNRG UCSF GRCh37 17 35930963 35930963 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 83 205 0 ENST00000339208.6:c.1120C>T p.Pro374Ser p.P374S ENST00000339208 NM_001163544.1 374 Cct/Tct 0 +SYT10 UCSF GRCh37 12 33532825 33532825 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 71 175 0 ENST00000228567.3:c.1442G>A p.Trp481Ter p.W481* ENST00000228567 NM_198992.3 481 tGg/tAg 0 +SZT2 UCSF GRCh37 1 43897534 43897534 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 45 120 0 ENST00000562955.1:c.5065G>A p.Val1689Ile p.V1689I ENST00000562955 NM_015284.3 1689 Gta/Ata 0 +TAAR5 UCSF GRCh37 6 132910054 132910054 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 74 122 0 ENST00000258034.2:c.772G>A p.Val258Met p.V258M ENST00000258034 NM_003967.2 258 Gtg/Atg 0 +TACC3 UCSF GRCh37 4 1730443 1730443 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 40 66 0 ENST00000313288.4:c.1314G>A p.Arg438= p.R438= ENST00000313288 NM_006342.2 438 agG/agA 0 +TACR1 UCSF GRCh37 2 75425842 75425842 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 82 156 0 ENST00000305249.5:c.219C>T p.Asn73= p.N73= ENST00000305249 NM_001058.3 73 aaC/aaT 0 +TACR2 UCSF GRCh37 10 71176015 71176015 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 52 94 0 ENST00000373306.4:c.65G>A p.Gly22Asp p.G22D ENST00000373306 NM_001057.2 22 gGc/gAc 0 +TAF1L UCSF GRCh37 9 32633141 32633141 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 120 113 215 1 ENST00000242310.4:c.2437C>T p.Pro813Ser p.P813S ENST00000242310 NM_153809.2 813 Cct/Tct 0 +TAF3 UCSF GRCh37 10 8007315 8007315 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 156 82 170 0 ENST00000344293.5:c.1842G>A p.Glu614= p.E614= ENST00000344293 NM_031923.3 614 gaG/gaA 0 +TAF5 UCSF GRCh37 10 105145228 105145228 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 46 108 0 ENST00000369839.3:c.1810G>A p.Gly604Ser p.G604S ENST00000369839 NM_006951.3 604 Ggc/Agc 0 +TAGLN2 UCSF GRCh37 1 159889463 159889463 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 73 161 0 ENST00000320307.4:c.343G>A p.Asp115Asn p.D115N ENST00000320307 NM_001277223.1 115 Gac/Aac 0 +TANC2 UCSF GRCh37 17 61489480 61489480 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0011 P10_Rec Untested WXS Illumina HiSeq 67 64 136 0 ENST00000424789.2:c.3665G>A p.Gly1222Glu p.G1222E ENST00000424789 NM_025185.3 1222 gGa/gAa 0 +TAPBP UCSF GRCh37 6 33281012 33281012 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 57 148 0 ENST00000426633.2:c.451C>T p.Leu151Phe p.L151F ENST00000426633 NM_172208.2 151 Ctc/Ttc 0 +TARSL2 UCSF GRCh37 15 102242566 102242566 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 94 179 0 ENST00000335968.3:c.1097G>A p.Gly366Asp p.G366D ENST00000335968 NM_152334.2 366 gGc/gAc 0 +TAS1R2 UCSF GRCh37 1 19186128 19186128 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 57 131 0 ENST00000375371.3:c.27C>T p.Ser9= p.S9= ENST00000375371 NM_152232.2 9 tcC/tcT 0 +TAS2R4 UCSF GRCh37 7 141479030 141479030 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 87 180 0 ENST00000247881.2:c.742G>A p.Val248Ile p.V248I ENST00000247881 NM_016944.1 248 Gtc/Atc 0 +TATDN2 UCSF GRCh37 3 10302232 10302232 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 88 166 0 ENST00000287652.4:c.826G>A p.Val276Ile p.V276I ENST00000287652 NM_014760.3 276 Gtt/Att 0 +TBC1D1 UCSF GRCh37 4 38134843 38134843 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 84 160 0 ENST00000261439.4:c.3271C>T p.Arg1091Cys p.R1091C ENST00000261439 NM_015173.3 1091 Cgc/Tgc 0 +TBC1D19 UCSF GRCh37 4 26737084 26737084 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 15 38 0 ENST00000264866.4:c.1092C>T p.Ile364= p.I364= ENST00000264866 NM_018317.2 364 atC/atT 0 +TBC1D24 UCSF GRCh37 16 2548319 2548319 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 16 13 34 0 ENST00000293970.5:c.1064C>T p.Ser355Phe p.S355F ENST00000293970 NM_001199107.1 355 tCc/tTc 0 +TBCEL UCSF GRCh37 11 120925837 120925837 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 75 155 0 ENST00000422003.2:c.532C>T p.Leu178= p.L178= ENST00000422003 NM_152715.3 178 Cta/Tta 0 +TBL1XR1 UCSF GRCh37 3 176763952 176763952 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 28 89 0 ENST00000430069.1:c.890C>T p.Thr297Ile p.T297I ENST00000430069 297 aCt/aTt 0 +TBX2 UCSF GRCh37 17 59485626 59485626 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 32 57 0 ENST00000240328.3:c.1898G>A p.Ser633Asn p.S633N ENST00000240328 NM_005994.3 633 aGc/aAc 0 +TBX4 UCSF GRCh37 17 59560522 59560522 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 71 119 0 ENST00000240335.1:c.1283G>A p.Ser428Asn p.S428N ENST00000240335 NM_018488.2 428 aGc/aAc 0 +TBXAS1 UCSF GRCh37 7 139661920 139661920 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 67 130 0 ENST00000336425.5:c.1022C>T p.Ala341Val p.A341V ENST00000336425 341 gCt/gTt 0 +TC2N UCSF GRCh37 14 92264214 92264214 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 54 134 0 ENST00000340892.5:c.770G>A p.Gly257Glu p.G257E ENST00000340892 NM_152332.4 257 gGa/gAa 0 +TCEB3 UCSF GRCh37 1 24077927 24077927 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 71 137 0 ENST00000418390.2:c.910G>A p.Glu304Lys p.E304K ENST00000418390 NM_003198.2 304 Gag/Aag 0 +TCF23 UCSF GRCh37 2 27375694 27375694 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 72 152 0 ENST00000296096.5:c.604C>T p.Leu202Phe p.L202F ENST00000296096 NM_175769.2 202 Ctt/Ttt 0 +TCTN3 UCSF GRCh37 10 97447086 97447086 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 42 90 0 ENST00000371217.5:c.654C>T p.Phe218= p.F218= ENST00000371217 218 ttC/ttT 0 +TCTN3 UCSF GRCh37 10 97453525 97453525 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 12 27 0 ENST00000371217.5:c.132C>T p.Gly44= p.G44= ENST00000371217 44 ggC/ggT 0 +TDRD1 UCSF GRCh37 10 115963291 115963291 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 84 178 0 ENST00000251864.2:c.946G>A p.Gly316Arg p.G316R ENST00000251864 NM_198795.1 316 Ggg/Agg 0 +TDRD5 UCSF GRCh37 1 179620034 179620034 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 81 223 0 ENST00000294848.8:c.1833C>T p.Phe611= p.F611= ENST00000294848 NM_173533.3 611 ttC/ttT 0 +TDRD7 UCSF GRCh37 9 100235884 100235884 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 126 73 178 0 ENST00000355295.4:c.2055G>A p.Lys685= p.K685= ENST00000355295 NM_014290.2 685 aaG/aaA 0 +TDRD9 UCSF GRCh37 14 104431696 104431696 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 57 155 1 ENST00000409874.4:c.447C>T p.Ser149= p.S149= ENST00000409874 NM_153046.2 149 tcC/tcT 0 +TDRD9 UCSF GRCh37 14 104465049 104465049 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 119 216 0 ENST00000409874.4:c.1467C>T p.Ser489= p.S489= ENST00000409874 NM_153046.2 489 agC/agT 0 +TECPR2 UCSF GRCh37 14 102900784 102900784 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 64 160 0 ENST00000359520.7:c.1630C>T p.Pro544Ser p.P544S ENST00000359520 NM_014844.3 544 Ccc/Tcc 0 +TECPR2 UCSF GRCh37 14 102916172 102916172 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 46 130 1 ENST00000359520.7:c.3282G>A p.Lys1094= p.K1094= ENST00000359520 NM_014844.3 1094 aaG/aaA 0 +TEF UCSF GRCh37 22 41783452 41783452 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 69 102 0 ENST00000266304.4:c.255G>A p.Lys85= p.K85= ENST00000266304 NM_003216.3 85 aaG/aaA 0 +TENC1 UCSF GRCh37 12 53453352 53453352 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 34 54 0 ENST00000314250.6:c.1927C>T p.Leu643Phe p.L643F ENST00000314250 NM_170754.2 643 Ctc/Ttc 0 +TENC1 UCSF GRCh37 12 53453006 53453006 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 28 33 0 ENST00000314250.6:c.1581C>T p.Ser527= p.S527= ENST00000314250 NM_170754.2 527 tcC/tcT 0 +TEP1 UCSF GRCh37 14 20851479 20851479 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 42 65 0 ENST00000262715.5:c.3901G>A p.Ala1301Thr p.A1301T ENST00000262715 NM_007110.4 1301 Gca/Aca 0 +TERF1 UCSF GRCh37 8 73921345 73921345 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 18 45 0 ENST00000276603.5:c.224C>T p.Ala75Val p.A75V ENST00000276603 NM_017489.2 75 gCc/gTc 0 +TET2 UCSF GRCh37 4 106190870 106190870 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 55 51 114 0 ENST00000380013.4:c.4148G>A p.Arg1383Lys p.R1383K ENST00000380013 NM_001127208.2 1383 aGa/aAa 0 +TET3 UCSF GRCh37 2 74274381 74274381 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 44 119 0 ENST00000409262.3:c.932C>T p.Pro311Leu p.P311L ENST00000409262 NM_144993.1 311 cCc/cTc 0 +TEX10 UCSF GRCh37 9 103109180 103109180 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 195 100 191 0 ENST00000374902.4:c.689G>A p.Arg230Lys p.R230K ENST00000374902 NM_017746.3 230 aGa/aAa 0 +TEX15 UCSF GRCh37 8 30705592 30705592 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 50 149 0 ENST00000256246.2:c.942C>T p.Thr314= p.T314= ENST00000256246 NM_031271.3 314 acC/acT 0 +TEX15 UCSF GRCh37 8 30706429 30706429 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 105 97 202 0 ENST00000256246.2:c.105C>T p.Asn35= p.N35= ENST00000256246 NM_031271.3 35 aaC/aaT 0 +TFE3 UCSF GRCh37 X 48895560 48895560 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 12 40 0 ENST00000315869.7:c.860C>T p.Thr287Ile p.T287I ENST00000315869 NM_006521.4 287 aCc/aTc 0 +TFEB UCSF GRCh37 6 41653940 41653940 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 74 133 0 ENST00000230323.4:c.839C>T p.Ala280Val p.A280V ENST00000230323 NM_007162.2 280 gCc/gTc 0 +TG UCSF GRCh37 8 134144104 134144104 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 204 73 119 0 ENST00000220616.4:c.7911C>T p.Tyr2637= p.Y2637= ENST00000220616 NM_003235.4 2637 taC/taT 0 +TG UCSF GRCh37 8 133919027 133919027 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 38 61 0 ENST00000220616.4:c.3729G>A p.Gln1243= p.Q1243= ENST00000220616 NM_003235.4 1243 caG/caA 0 +TGFA UCSF GRCh37 2 70683575 70683575 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 11 26 0 ENST00000295400.6:c.261C>T p.Leu87= p.L87= ENST00000295400 NM_001099691.2 87 ctC/ctT 0 +TGFB1 UCSF GRCh37 19 41854289 41854289 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 84 165 0 ENST00000221930.5:c.427G>A p.Ala143Thr p.A143T ENST00000221930 NM_000660.4 143 Gcg/Acg 0 +TGFBR3 UCSF GRCh37 1 92262859 92262859 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 78 187 0 ENST00000212355.4:c.231C>T p.Gly77= p.G77= ENST00000212355 NM_001195683.1 77 ggC/ggT 0 +TGIF2LX UCSF GRCh37 X 89177490 89177490 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 67 152 0 ENST00000283891.5:c.406C>T p.Gln136Ter p.Q136* ENST00000283891 NM_138960.3 136 Cag/Tag 0 +TGM3 UCSF GRCh37 20 2290834 2290834 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 75 184 0 ENST00000381458.5:c.192C>T p.Pro64= p.P64= ENST00000381458 NM_003245.3 64 ccC/ccT 0 +THADA UCSF GRCh37 2 43655362 43655362 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 82 186 1 ENST00000405006.4:c.3935G>A p.Gly1312Glu p.G1312E ENST00000405006 NM_001083953.1 1312 gGa/gAa 0 +THBS2 UCSF GRCh37 6 169637393 169637393 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 32 81 0 ENST00000366787.3:c.1349C>T p.Ser450Phe p.S450F ENST00000366787 NM_003247.2 450 tCt/tTt 0 +THEG UCSF GRCh37 19 375960 375960 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 31 51 0 ENST00000342640.4:c.11G>A p.Ser4Asn p.S4N ENST00000342640 NM_016585.4 4 aGc/aAc 0 +THOC2 UCSF GRCh37 X 122759802 122759802 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 66 164 0 ENST00000245838.8:c.3018G>A p.Gln1006= p.Q1006= ENST00000245838 NM_001081550.1 1006 caG/caA 0 +THSD7A UCSF GRCh37 7 11468604 11468604 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 136 127 204 0 ENST00000423059.4:c.3213G>A p.Arg1071= p.R1071= ENST00000423059 NM_015204.2 1071 agG/agA 0 +THSD7B UCSF GRCh37 2 138169344 138169344 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 149 129 247 0 ENST00000272643.3:c.2861C>T p.Ala954Val p.A954V ENST00000272643 954 gCa/gTa 0 +THUMPD1 UCSF GRCh37 16 20750362 20750362 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 78 146 0 ENST00000381337.2:c.263G>A p.Ser88Asn p.S88N ENST00000381337 NM_017736.3 88 aGt/aAt 0 +TIA1 UCSF GRCh37 2 70443408 70443408 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 26 51 0 ENST00000433529.2:c.696G>A p.Gln232= p.Q232= ENST00000433529 NM_022173.2 232 caG/caA 0 +TIAM1 UCSF GRCh37 21 32525434 32525434 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 67 173 0 ENST00000286827.3:c.3190G>A p.Glu1064Lys p.E1064K ENST00000286827 NM_003253.2 1064 Gag/Aag 0 +TIGD5 UCSF GRCh37 8 144680339 144680339 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 4 9 0 ENST00000321385.3:c.119G>A p.Arg40His p.R40H ENST00000321385 40 cGc/cAc 0 +TIMELESS UCSF GRCh37 12 56826196 56826196 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 75 153 0 ENST00000553532.1:c.644G>A p.Ser215Asn p.S215N ENST00000553532 215 aGc/aAc 0 +TIMELESS UCSF GRCh37 12 56811993 56811993 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 124 94 182 0 ENST00000553532.1:c.3379A>G p.Lys1127Glu p.K1127E ENST00000553532 1127 Aaa/Gaa 0 +TJP2 UCSF GRCh37 9 71869199 71869199 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 154 80 138 0 ENST00000377245.4:c.3482C>T p.Ala1161Val p.A1161V ENST00000377245 NM_004817.3 1161 gCc/gTc 0 +TJP2 UCSF GRCh37 9 71849405 71849405 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 45 137 0 ENST00000377245.4:c.1722C>T p.Tyr574= p.Y574= ENST00000377245 NM_004817.3 574 taC/taT 0 +TKTL2 UCSF GRCh37 4 164393404 164393404 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 78 159 0 ENST00000280605.3:c.1483C>T p.Gln495Ter p.Q495* ENST00000280605 NM_032136.4 495 Cag/Tag 0 +TLK1 UCSF GRCh37 2 171884884 171884884 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 45 123 0 ENST00000431350.2:c.1201G>A p.Glu401Lys p.E401K ENST00000431350 401 Gaa/Aaa 0 +TLK1 UCSF GRCh37 2 171871453 171871453 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 78 188 0 ENST00000431350.2:c.1242G>A p.Glu414= p.E414= ENST00000431350 414 gaG/gaA 0 +TLL1 UCSF GRCh37 4 166981289 166981289 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 40 146 0 ENST00000061240.2:c.1956C>T p.Thr652= p.T652= ENST00000061240 NM_012464.4 652 acC/acT 0 +TLL2 UCSF GRCh37 10 98157046 98157046 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0015 P10_Rec Untested WXS Illumina HiSeq 54 43 81 0 ENST00000357947.3:c.1281C>T p.Gly427= p.G427= ENST00000357947 NM_012465.3 427 ggC/ggT 0 +TLN1 UCSF GRCh37 9 35725306 35725306 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 41 77 0 ENST00000314888.9:c.143G>A p.Gly48Glu p.G48E ENST00000314888 NM_006289.3 48 gGg/gAg 0 +TLN2 UCSF GRCh37 15 63008649 63008649 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 37 91 0 ENST00000306829.6:c.2754C>T p.Asn918= p.N918= ENST00000306829 NM_015059.2 918 aaC/aaT 0 +TLN2 UCSF GRCh37 15 63088326 63088326 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 40 98 0 ENST00000306829.6:c.5884G>A p.Val1962Ile p.V1962I ENST00000306829 NM_015059.2 1962 Gtc/Atc 0 +TM7SF3 UCSF GRCh37 12 27148236 27148236 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 65 135 0 ENST00000343028.4:c.624G>A p.Glu208= p.E208= ENST00000343028 NM_016551.2 208 gaG/gaA 0 +TMC2 UCSF GRCh37 20 2593935 2593935 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 51 120 0 ENST00000358864.1:c.1839C>T p.Asn613= p.N613= ENST00000358864 NM_080751.2 613 aaC/aaT 0 +TMC6 UCSF GRCh37 17 76118775 76118775 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 15 41 0 ENST00000322914.3:c.1138G>A p.Ala380Thr p.A380T ENST00000322914 NM_007267.6 380 Gcc/Acc 0 +TMC6 UCSF GRCh37 17 76116781 76116781 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 125 88 193 0 ENST00000322914.3:c.1668C>T p.Asp556= p.D556= ENST00000322914 NM_007267.6 556 gaC/gaT 0 +TMEM121 UCSF GRCh37 14 105995323 105995323 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 13 14 0 ENST00000392519.2:c.152G>A p.Cys51Tyr p.C51Y ENST00000392519 NM_025268.2 51 tGc/tAc 0 +TMEM131 UCSF GRCh37 2 98408904 98408904 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 17 40 0 ENST00000186436.5:c.4089C>T p.Ser1363= p.S1363= ENST00000186436 NM_015348.1 1363 tcC/tcT 0 +TMEM132C UCSF GRCh37 12 129190605 129190605 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 18 23 32 0 ENST00000435159.2:c.3092C>T p.Ser1031Phe p.S1031F ENST00000435159 NM_001136103.2 1031 tCc/tTc 0 +TMEM139 UCSF GRCh37 7 142983697 142983697 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 91 163 0 ENST00000359333.3:c.426G>A p.Arg142= p.R142= ENST00000359333 NM_001282876.1 142 agG/agA 0 +TMEM156 UCSF GRCh37 4 38995377 38995377 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 90 184 0 ENST00000381938.3:c.600C>T p.His200= p.H200= ENST00000381938 NM_024943.1 200 caC/caT 0 +TMEM201 UCSF GRCh37 1 9661350 9661350 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 50 84 0 ENST00000340381.6:c.794C>T p.Thr265Ile p.T265I ENST00000340381 NM_001130924.2 265 aCc/aTc 0 +TMEM205 UCSF GRCh37 19 11453739 11453739 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 37 71 0 ENST00000354882.5:c.322C>T p.Pro108Ser p.P108S ENST00000354882 108 Ccc/Tcc 0 +TMEM214 UCSF GRCh37 2 27261943 27261943 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 38 90 0 ENST00000238788.9:c.1436G>A p.Arg479Gln p.R479Q ENST00000238788 NM_017727.4 479 cGg/cAg 0 +TMEM232 UCSF GRCh37 5 109963542 109963542 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 37 84 0 ENST00000455884.2:c.541C>T p.Leu181= p.L181= ENST00000455884 181 Ctg/Ttg 0 +TMEM234 UCSF GRCh37 1 32682944 32682944 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 56 100 0 ENST00000344461.3:c.244C>T p.Leu82= p.L82= ENST00000344461 82 Ctg/Ttg 0 +TMEM237 UCSF GRCh37 2 202496808 202496808 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 126 97 216 0 ENST00000409883.2:c.519C>T p.Ser173= p.S173= ENST00000409883 NM_001044385.2 173 agC/agT 0 +TMEM38A UCSF GRCh37 19 16772124 16772124 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 10 10 0 ENST00000187762.2:c.96C>T p.Val32= p.V32= ENST00000187762 NM_024074.1 32 gtC/gtT 0 +TMEM47 UCSF GRCh37 X 34657462 34657462 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 44 77 0 ENST00000275954.3:c.269C>T p.Ala90Val p.A90V ENST00000275954 NM_031442.3 90 gCc/gTc 0 +TMEM59L UCSF GRCh37 19 18728993 18728993 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 27 96 0 ENST00000262817.3:c.693G>A p.Arg231= p.R231= ENST00000262817 NM_012109.2 231 agG/agA 0 +TMEM74 UCSF GRCh37 8 109796546 109796546 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 187 70 134 0 ENST00000297459.3:c.782G>A p.Arg261His p.R261H ENST00000297459 NM_153015.1 261 cGt/cAt 0 +TMPRSS15 UCSF GRCh37 21 19713814 19713814 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 79 177 0 ENST00000284885.3:c.1480G>A p.Asp494Asn p.D494N ENST00000284885 NM_002772.2 494 Gac/Aac 0 +TMTC3 UCSF GRCh37 12 88582692 88582692 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 58 128 0 ENST00000266712.6:c.1505C>T p.Ser502Phe p.S502F ENST00000266712 NM_181783.3 502 tCt/tTt 0 +TMUB1 UCSF GRCh37 7 150778822 150778822 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 9 15 0 ENST00000297533.4:c.555G>A p.Gly185= p.G185= ENST00000297533 NM_001136044.1 185 ggG/ggA 0 +TNC UCSF GRCh37 9 117808778 117808778 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 231 96 219 0 ENST00000350763.4:c.5036G>A p.Gly1679Asp p.G1679D ENST00000350763 NM_002160.3 1679 gGt/gAt 0 +TNC UCSF GRCh37 9 117826119 117826119 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 151 65 159 0 ENST00000350763.4:c.3716C>T p.Thr1239Ile p.T1239I ENST00000350763 NM_002160.3 1239 aCt/aTt 0 +TNC UCSF GRCh37 9 117848837 117848837 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 163 74 124 0 ENST00000350763.4:c.1173G>A p.Arg391= p.R391= ENST00000350763 NM_002160.3 391 cgG/cgA 0 +TNFRSF11A UCSF GRCh37 18 60036604 60036604 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 53 49 98 0 ENST00000586569.1:c.1454G>A p.Ser485Asn p.S485N ENST00000586569 NM_001278268.1 485 aGc/aAc 0 +TNFRSF11B UCSF GRCh37 8 119945463 119945463 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 292 79 206 0 ENST00000297350.4:c.107C>T p.Ser36Phe p.S36F ENST00000297350 NM_002546.3 36 tCt/tTt 0 +TNFRSF1B UCSF GRCh37 1 12266822 12266822 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 43 93 0 ENST00000376259.3:c.1131C>T p.Thr377= p.T377= ENST00000376259 NM_001066.2 377 acC/acT 0 +TNIP1 UCSF GRCh37 5 150443200 150443200 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 57 111 0 ENST00000315050.7:c.245C>T p.Ser82Phe p.S82F ENST00000315050 NM_001252391.1 82 tCc/tTc 0 +TNK1 UCSF GRCh37 17 7286633 7286633 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 85 169 0 ENST00000576812.1:c.228C>T p.Val76= p.V76= ENST00000576812 NM_001251902.1 76 gtC/gtT 0 +TNK2 UCSF GRCh37 3 195594767 195594767 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 9 17 0 ENST00000333602.6:c.2357C>T p.Pro786Leu p.P786L ENST00000333602 NM_005781.4 786 cCt/cTt 0 +TNKS1BP1 UCSF GRCh37 11 57069696 57069696 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 41 64 0 ENST00000358252.3:c.4686C>T p.Asp1562= p.D1562= ENST00000358252 NM_033396.2 1562 gaC/gaT 0 +TNNT2 UCSF GRCh37 1 201331124 201331124 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 64 152 0 ENST00000236918.7:c.621G>A p.Gln207= p.Q207= ENST00000236918 207 caG/caA 0 +TNRC6A UCSF GRCh37 16 24788512 24788512 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 91 166 0 ENST00000395799.3:c.422G>A p.Arg141His p.R141H ENST00000395799 NM_014494.2 141 cGc/cAc 0 +TNRC6A UCSF GRCh37 16 24802403 24802403 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 38 122 0 ENST00000395799.3:c.2440G>A p.Val814Ile p.V814I ENST00000395799 NM_014494.2 814 Gtc/Atc 0 +TNS4 UCSF GRCh37 17 38636093 38636093 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 29 33 0 ENST00000254051.6:c.1743C>T p.Gly581= p.G581= ENST00000254051 NM_032865.5 581 ggC/ggT 0 +TOP3A UCSF GRCh37 17 18208448 18208448 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 62 126 0 ENST00000321105.5:c.477G>A p.Glu159= p.E159= ENST00000321105 NM_004618.3 159 gaG/gaA 0 +TOPBP1 UCSF GRCh37 3 133320145 133320145 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 59 139 0 ENST00000260810.5:c.4518G>A p.Lys1506= p.K1506= ENST00000260810 NM_007027.3 1506 aaG/aaA 0 +TOR2A UCSF GRCh37 9 130495707 130495707 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 49 94 0 ENST00000373284.5:c.550G>A p.Val184Ile p.V184I ENST00000373284 NM_001085347.2 184 Gta/Ata 0 +TOX UCSF GRCh37 8 59728200 59728200 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 44 106 0 ENST00000361421.1:c.1089C>T p.Ser363= p.S363= ENST00000361421 NM_014729.2 363 agC/agT 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 1 82 83 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TP53BP1 UCSF GRCh37 15 43769868 43769868 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 68 171 0 ENST00000263801.3:c.863G>A p.Gly288Glu p.G288E ENST00000263801 NM_005657.2 288 gGa/gAa 0 +TP53BP2 UCSF GRCh37 1 223983936 223983936 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 91 150 0 ENST00000343537.7:c.2305G>A p.Glu769Lys p.E769K ENST00000343537 NM_001031685.2 769 Gag/Aag 0 +TP63 UCSF GRCh37 3 189455553 189455553 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 65 166 0 ENST00000264731.3:c.87C>T p.Phe29= p.F29= ENST00000264731 NM_003722.4 29 ttC/ttT 0 +TP73 UCSF GRCh37 1 3645890 3645890 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 35 57 0 ENST00000378295.4:c.1075-1G>A p.X359_splice ENST00000378295 NM_005427.3 0 +TPCN2 UCSF GRCh37 11 68840393 68840393 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 39 86 0 ENST00000294309.3:c.1154C>T p.Ser385Phe p.S385F ENST00000294309 NM_139075.3 385 tCc/tTc 0 +TPRN UCSF GRCh37 9 140086761 140086761 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0039 P10_Rec Untested WXS Illumina HiSeq 74 26 61 0 ENST00000409012.4:c.2023G>A p.Ala675Thr p.A675T ENST00000409012 NM_001128228.2 675 Gcg/Acg 0 +TPRN UCSF GRCh37 9 140087087 140087087 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 43 95 0 ENST00000409012.4:c.1782G>A p.Glu594= p.E594= ENST00000409012 NM_001128228.2 594 gaG/gaA 0 +TRABD UCSF GRCh37 22 50635990 50635990 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 46 76 0 ENST00000303434.4:c.644G>A p.Gly215Asp p.G215D ENST00000303434 NM_025204.2 215 gGc/gAc 0 +TRAF3IP3 UCSF GRCh37 1 209933650 209933650 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 25 39 0 ENST00000367024.1:c.266C>T p.Pro89Leu p.P89L ENST00000367024 89 cCc/cTc 0 +TRANK1 UCSF GRCh37 3 36873744 36873744 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 137 200 0 ENST00000429976.2:c.7198C>T p.Pro2400Ser p.P2400S ENST00000429976 2400 Cca/Tca 0 +TRAPPC6B UCSF GRCh37 14 39628700 39628700 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 43 134 0 ENST00000330149.5:c.136G>A p.Gly46Arg p.G46R ENST00000330149 NM_001079537.1 46 Gga/Aga 0 +TRAPPC9 UCSF GRCh37 8 141461167 141461167 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 294 71 138 0 ENST00000438773.2:c.306G>A p.Gln102= p.Q102= ENST00000438773 NM_001160372.1 102 caG/caA 0 +TRDMT1 UCSF GRCh37 10 17195563 17195563 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 52 114 0 ENST00000377799.3:c.1018C>T p.Leu340= p.L340= ENST00000377799 NM_004412.5 340 Ctg/Ttg 0 +TREM1 UCSF GRCh37 6 41248854 41248854 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 42 114 0 ENST00000244709.4:c.444C>T p.Thr148= p.T148= ENST00000244709 NM_018643.3 148 acC/acT 0 +TREM2 UCSF GRCh37 6 41127546 41127546 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 25 83 0 ENST00000373113.3:c.466G>A p.Glu156Lys p.E156K ENST00000373113 NM_018965.3 156 Gag/Aag 0 +TREML1 UCSF GRCh37 6 41117489 41117489 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 80 135 0 ENST00000426005.2:c.789C>T p.Ser263= p.S263= ENST00000426005 NM_178174.3 263 tcC/tcT 0 +TRHDE UCSF GRCh37 12 72667167 72667167 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 45 87 0 ENST00000261180.4:c.609C>T p.Val203= p.V203= ENST00000261180 NM_013381.2 203 gtC/gtT 0 +TRIM15 UCSF GRCh37 6 30131780 30131780 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 35 81 0 ENST00000376694.4:c.319G>A p.Glu107Lys p.E107K ENST00000376694 NM_033229.2 107 Gag/Aag 0 +TRIM16L UCSF GRCh37 17 18630996 18630996 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 80 161 0 ENST00000395671.4:c.126G>A p.Arg42= p.R42= ENST00000395671 NM_001037330.1 42 agG/agA 0 +TRIM33 UCSF GRCh37 1 114952805 114952805 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 70 142 0 ENST00000358465.2:c.2194+1G>A p.X732_splice ENST00000358465 NM_015906.3 0 +TRIM42 UCSF GRCh37 3 140407071 140407071 + missense_variant Missense_Mutation SNP T T G NOVEL P10_Rec Untested WXS Illumina HiSeq 85 65 156 0 ENST00000286349.3:c.1547T>G p.Ile516Ser p.I516S ENST00000286349 NM_152616.4 516 aTt/aGt 0 +TRIM50 UCSF GRCh37 7 72727137 72727137 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 9 14 0 ENST00000333149.2:c.1244G>A p.Gly415Glu p.G415E ENST00000333149 NM_001281450.1 415 gGg/gAg 0 +TRIM55 UCSF GRCh37 8 67040642 67040642 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 65 174 0 ENST00000315962.4:c.272G>A p.Gly91Glu p.G91E ENST00000315962 NM_184085.1 91 gGg/gAg 0 +TRIM7 UCSF GRCh37 5 180622331 180622331 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 16 31 0 ENST00000274773.7:c.1371C>T p.His457= p.H457= ENST00000274773 NM_203293.2 457 caC/caT 0 +TRIML1 UCSF GRCh37 4 189060893 189060893 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 79 154 0 ENST00000332517.3:c.181G>A p.Glu61Lys p.E61K ENST00000332517 NM_178556.3 61 Gag/Aag 0 +TRIOBP UCSF GRCh37 22 38106452 38106452 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 26 35 0 ENST00000406386.3:c.133G>A p.Gly45Ser p.G45S ENST00000406386 NM_001039141.2 45 Ggt/Agt 0 +TRIOBP UCSF GRCh37 22 38119897 38119897 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 97 201 0 ENST00000406386.3:c.1334G>A p.Arg445Lys p.R445K ENST00000406386 NM_001039141.2 445 aGa/aAa 0 +TRMT11 UCSF GRCh37 6 126319699 126319699 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 54 134 0 ENST00000334379.5:c.391C>T p.Leu131Phe p.L131F ENST00000334379 NM_001031712.2 131 Ctt/Ttt 0 +TRNAU1AP UCSF GRCh37 1 28891228 28891228 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 82 182 0 ENST00000373830.3:c.292C>T p.Leu98Phe p.L98F ENST00000373830 NM_017846.4 98 Ctc/Ttc 0 +TRO UCSF GRCh37 X 54949889 54949889 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 26 48 0 ENST00000173898.7:c.924G>A p.Arg308= p.R308= ENST00000173898 NM_001039705.2 308 agG/agA 0 +TRPC3 UCSF GRCh37 4 122803559 122803559 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 20 124 0 ENST00000379645.3:c.2573G>A p.Arg858Gln p.R858Q ENST00000379645 NM_001130698.1 858 cGg/cAg 0 +TRPC5 UCSF GRCh37 X 111195523 111195523 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 65 151 0 ENST00000262839.2:c.126G>A p.Lys42= p.K42= ENST00000262839 NM_012471.2 42 aaG/aaA 0 +TRPM2 UCSF GRCh37 21 45784113 45784113 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 61 145 0 ENST00000300482.5:c.371C>T p.Thr124Ile p.T124I ENST00000300482 124 aCc/aTc 0 +TRPM2 UCSF GRCh37 21 45826605 45826605 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 10 22 0 ENST00000300482.5:c.2919C>T p.His973= p.H973= ENST00000300482 973 caC/caT 0 +TRPM2 UCSF GRCh37 21 45825063 45825063 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 57 123 0 ENST00000300482.5:c.2577G>A p.Lys859= p.K859= ENST00000300482 859 aaG/aaA 0 +TRPM3 UCSF GRCh37 9 73150932 73150932 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 232 116 188 0 ENST00000377110.3:c.5061C>T p.Ser1687= p.S1687= ENST00000377110 1687 agC/agT 0 +TRPM3 UCSF GRCh37 9 73167824 73167824 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 192 94 200 0 ENST00000377110.3:c.3474C>T p.Phe1158= p.F1158= ENST00000377110 1158 ttC/ttT 0 +TRPM4 UCSF GRCh37 19 49714491 49714491 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 14 10 0 ENST00000252826.5:c.3605G>A p.Gly1202Asp p.G1202D ENST00000252826 NM_017636.3 1202 gGt/gAt 0 +TRPM4 UCSF GRCh37 19 49675322 49675322 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 52 128 0 ENST00000252826.5:c.1107G>A p.Gly369= p.G369= ENST00000252826 NM_017636.3 369 ggG/ggA 0 +TRPM6 UCSF GRCh37 9 77353524 77353524 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 54 119 0 ENST00000360774.1:c.5575C>T p.Leu1859= p.L1859= ENST00000360774 NM_017662.4 1859 Ctg/Ttg 0 +TRPS1 UCSF GRCh37 8 116426543 116426543 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 157 55 131 0 ENST00000220888.5:c.3554C>T p.Thr1185Met p.T1185M ENST00000220888 1185 aCg/aTg 0 +TRPV6 UCSF GRCh37 7 142572668 142572668 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 73 133 0 ENST00000359396.3:c.1275C>T p.Phe425= p.F425= ENST00000359396 NM_018646.4 425 ttC/ttT 0 +TRUB2 UCSF GRCh37 9 131071985 131071985 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 41 95 0 ENST00000372890.4:c.840G>A p.Gln280= p.Q280= ENST00000372890 NM_015679.1 280 caG/caA 0 +TSC1 UCSF GRCh37 9 135781026 135781026 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 173 80 182 0 ENST00000298552.3:c.1939G>A p.Glu647Lys p.E647K ENST00000298552 NM_001162426.1 647 Gaa/Aaa 0 +TSEN34 UCSF GRCh37 19 54695758 54695758 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 46 88 0 ENST00000302937.4:c.430G>A p.Ala144Thr p.A144T ENST00000302937 NM_024075.3 144 Gct/Act 0 +TSGA10 UCSF GRCh37 2 99635071 99635071 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 31 59 0 ENST00000355053.4:c.1850G>A p.Arg617Lys p.R617K ENST00000355053 NM_182911.3 617 aGa/aAa 0 +TSGA10IP UCSF GRCh37 11 65714692 65714692 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 23 47 0 ENST00000532620.1:n.627C>T *209* ENST00000532620 0 +TSHZ3 UCSF GRCh37 19 31768300 31768300 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 64 129 0 ENST00000240587.4:c.2399G>A p.Gly800Asp p.G800D ENST00000240587 NM_020856.2 800 gGc/gAc 0 +TSNARE1 UCSF GRCh37 8 143356193 143356193 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 8 15 0 ENST00000524325.1:c.1392C>T p.Ser464= p.S464= ENST00000524325 464 tcC/tcT 0 +TSNARE1 UCSF GRCh37 8 143427177 143427177 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 157 34 58 0 ENST00000524325.1:c.165C>T p.Arg55= p.R55= ENST00000524325 55 cgC/cgT 0 +TSPAN10 UCSF GRCh37 17 79612306 79612306 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 39 91 0 ENST00000328585.4:c.325G>A p.Gly109Arg p.G109R ENST00000328585 NM_031945.3 109 Gga/Aga 0 +TSPAN12 UCSF GRCh37 7 120450610 120450610 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 39 127 0 ENST00000222747.3:c.375G>A p.Trp125Ter p.W125* ENST00000222747 NM_012338.3 125 tgG/tgA 0 +TSPAN16 UCSF GRCh37 19 11422816 11422816 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 23 57 0 ENST00000316737.1:c.605G>A p.Gly202Asp p.G202D ENST00000316737 NM_012466.2 202 gGc/gAc 0 +TSSK1B UCSF GRCh37 5 112770079 112770079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 83 160 0 ENST00000390666.3:c.458C>T p.Ser153Phe p.S153F ENST00000390666 NM_032028.3 153 tCc/tTc 0 +TSSK3 UCSF GRCh37 1 32829748 32829748 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 74 143 0 ENST00000373534.3:c.698G>A p.Ser233Asn p.S233N ENST00000373534 NM_052841.3 233 aGc/aAc 0 +TSTA3 UCSF GRCh37 8 144695091 144695091 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 14 20 0 ENST00000425753.2:c.955G>A p.Ala319Thr p.A319T ENST00000425753 NM_003313.3 319 Gcc/Acc 0 +TSTA3 UCSF GRCh37 8 144698311 144698311 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 324 75 155 0 ENST00000425753.2:c.226C>T p.Leu76= p.L76= ENST00000425753 NM_003313.3 76 Ctg/Ttg 0 +TSTD2 UCSF GRCh37 9 100373856 100373856 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 172 79 160 0 ENST00000341170.4:c.729G>A p.Lys243= p.K243= ENST00000341170 NM_139246.4 243 aaG/aaA 0 +TTBK2 UCSF GRCh37 15 43038251 43038251 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 58 144 0 ENST00000267890.6:c.3477C>T p.Ser1159= p.S1159= ENST00000267890 NM_173500.3 1159 tcC/tcT 0 +TTC17 UCSF GRCh37 11 43429077 43429077 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 44 110 0 ENST00000039989.4:c.2014C>T p.Leu672Phe p.L672F ENST00000039989 NM_018259.5 672 Ctt/Ttt 0 +TTC18 UCSF GRCh37 10 75053137 75053137 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 68 131 0 ENST00000310715.3:c.1864G>A p.Asp622Asn p.D622N ENST00000310715 NM_145170.3 622 Gat/Aat 0 +TTC24 UCSF GRCh37 1 156555537 156555537 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 123 204 0 ENST00000368236.3:c.1489C>T p.His497Tyr p.H497Y ENST00000368236 NM_001105669.2 497 Cac/Tac 0 +TTC26 UCSF GRCh37 7 138865855 138865855 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 59 105 0 ENST00000464848.1:c.1330C>T p.Pro444Ser p.P444S ENST00000464848 NM_001287513.1 444 Cca/Tca 0 +TTC28 UCSF GRCh37 22 28389370 28389370 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 10 25 0 ENST00000397906.2:c.5381C>T p.Pro1794Leu p.P1794L ENST00000397906 NM_001145418.1 1794 cCc/cTc 0 +TTC28 UCSF GRCh37 22 28494902 28494902 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 50 88 0 ENST00000397906.2:c.3547+1G>A p.X1183_splice ENST00000397906 NM_001145418.1 0 +TTC3 UCSF GRCh37 21 38538141 38538141 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 114 203 0 ENST00000354749.2:c.3625C>T p.Pro1209Ser p.P1209S ENST00000354749 1209 Cca/Tca 0 +TTC38 UCSF GRCh37 22 46679926 46679926 + synonymous_variant Silent SNP G G A snp132_rs5768270 P10_Rec Untested WXS Illumina HiSeq 9 81 203 0 ENST00000381031.3:c.792G>A p.Glu264= p.E264= ENST00000381031 NM_017931.2 264 gaG/gaA 0 +TTC7B UCSF GRCh37 14 91211201 91211201 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 58 149 0 ENST00000328459.6:c.511G>A p.Asp171Asn p.D171N ENST00000328459 NM_001010854.1 171 Gat/Aat 0 +TTLL2 UCSF GRCh37 6 167753706 167753706 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 63 102 0 ENST00000239587.5:c.318G>A p.Arg106= p.R106= ENST00000239587 NM_031949.4 106 agG/agA 0 +TTLL5 UCSF GRCh37 14 76165563 76165563 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 35 83 0 ENST00000298832.9:c.535G>A p.Val179Ile p.V179I ENST00000298832 NM_015072.4 179 Gta/Ata 0 +TTLL7 UCSF GRCh37 1 84335694 84335694 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 59 119 0 ENST00000260505.8:c.2615G>A p.Gly872Glu p.G872E ENST00000260505 NM_024686.4 872 gGa/gAa 0 +TTN UCSF GRCh37 2 179403718 179403718 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 64 169 0 ENST00000591111.1:c.94021G>A p.Glu31341Lys p.E31341K ENST00000591111 31341 Gag/Aag 0 +TTN UCSF GRCh37 2 179616401 179616401 + intron_variant Intron SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 81 197 0 ENST00000591111.1:c.10360+1450G>A *3454* ENST00000591111 0 +TTN UCSF GRCh37 2 179469033 179469033 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 58 128 0 ENST00000591111.1:c.49459-1G>A p.X16487_splice ENST00000591111 0 +TTN UCSF GRCh37 2 179629420 179629420 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 71 174 0 ENST00000591111.1:c.9822G>A p.Lys3274= p.K3274= ENST00000591111 3274 aaG/aaA 0 +TUBD1 UCSF GRCh37 17 57963589 57963589 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 50 112 0 ENST00000325752.3:c.175C>T p.Pro59Ser p.P59S ENST00000325752 NM_016261.3 59 Cca/Tca 0 +TUBGCP3 UCSF GRCh37 13 113176698 113176698 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 63 150 0 ENST00000261965.3:c.1681G>A p.Ala561Thr p.A561T ENST00000261965 NM_006322.4 561 Gca/Aca 0 +TULP3 UCSF GRCh37 12 3046829 3046829 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 11 55 0 ENST00000448120.2:c.957G>A p.Arg319= p.R319= ENST00000448120 NM_003324.4 319 agG/agA 0 +TUSC3 UCSF GRCh37 8 15398061 15398061 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 18 41 0 ENST00000503731.1:c.122G>A p.Gly41Glu p.G41E ENST00000503731 NM_006765.3 41 gGa/gAa 0 +TWF2 UCSF GRCh37 3 52263952 52263952 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 36 59 0 ENST00000305533.5:c.744C>T p.Asp248= p.D248= ENST00000305533 NM_007284.3 248 gaC/gaT 0 +TXLNG UCSF GRCh37 X 16847817 16847817 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 67 159 0 ENST00000380122.5:c.788C>T p.Ala263Val p.A263V ENST00000380122 NM_018360.2 263 gCc/gTc 0 +TXNDC17 UCSF GRCh37 17 6546334 6546334 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 54 128 0 ENST00000250101.5:c.367G>A p.Asp123Asn p.D123N ENST00000250101 NM_032731.3 123 Gat/Aat 0 +TXNDC2 UCSF GRCh37 18 9887505 9887505 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 123 118 231 0 ENST00000306084.6:c.1029C>T p.Asp343= p.D343= ENST00000306084 NM_001098529.1 343 gaC/gaT 0 +UBE3C UCSF GRCh37 7 156967682 156967682 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 110 217 0 ENST00000348165.5:c.412C>T p.Leu138Phe p.L138F ENST00000348165 NM_014671.2 138 Ctt/Ttt 0 +UBR2 UCSF GRCh37 6 42658896 42658896 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 84 163 0 ENST00000372899.1:c.5253C>T p.Asp1751= p.D1751= ENST00000372899 NM_015255.2 1751 gaC/gaT 0 +UBR3 UCSF GRCh37 2 170806358 170806358 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 146 112 233 0 ENST00000272793.5:c.3328C>T p.Pro1110Ser p.P1110S ENST00000272793 1110 Cct/Tct 0 +UBR5 UCSF GRCh37 8 103323703 103323703 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 195 61 153 0 ENST00000520539.1:c.2440G>A p.Asp814Asn p.D814N ENST00000520539 NM_015902.5 814 Gat/Aat 0 +UBXN11 UCSF GRCh37 1 26609419 26609419 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 40 80 0 ENST00000374221.3:c.1087C>T p.Pro363Ser p.P363S ENST00000374221 NM_183008.2 363 Cca/Tca 0 +UBXN2B UCSF GRCh37 8 59346977 59346977 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 32 65 0 ENST00000399598.2:c.447G>A p.Trp149Ter p.W149* ENST00000399598 NM_001077619.1 149 tgG/tgA 0 +UCK1 UCSF GRCh37 9 134404345 134404345 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 41 44 0 ENST00000372215.4:c.589G>A p.Glu197Lys p.E197K ENST00000372215 NM_031432.2 197 Gag/Aag 0 +UGCG UCSF GRCh37 9 114676906 114676906 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 152 53 172 0 ENST00000374279.3:c.120G>A p.Lys40= p.K40= ENST00000374279 NM_003358.1 40 aaG/aaA 0 +UGT1A4 UCSF GRCh37 2 234627943 234627943 + synonymous_variant Silent SNP G G A snp132_rs45467894 P10_Rec Untested WXS Illumina HiSeq 226 36 222 0 ENST00000373409.3:c.477G>A p.Ala159= p.A159= ENST00000373409 NM_007120.2 159 gcG/gcA 0 +UGT1A7 UCSF GRCh37 2 234590941 234590942 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 0 ENST00000373426.3:c.364dup p.Ser122PhefsTer8 p.S122Ffs*8 ENST00000373426 NM_019077.2 120 ttt/tTtt 0 +UGT2A1 UCSF GRCh37 4 70512715 70512715 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 58 154 0 ENST00000503640.1:c.648C>T p.Tyr216= p.Y216= ENST00000503640 NM_006798.3 216 taC/taT 0 +UGT2B10 UCSF GRCh37 4 69886008 69886008 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 146 111 259 0 ENST00000505092.1:n.125G>A *42* ENST00000505092 0 +UHRF2 UCSF GRCh37 9 6413522 6413522 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 13 43 0 ENST00000276893.5:c.32C>T p.Ser11Phe p.S11F ENST00000276893 NM_152896.2 11 tCc/tTc 0 +ULK2 UCSF GRCh37 17 19689373 19689373 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 58 124 0 ENST00000361658.2:c.2128C>T p.Leu710= p.L710= ENST00000361658 NM_001142610.1 710 Ctg/Ttg 0 +UMOD UCSF GRCh37 16 20357622 20357622 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 37 135 0 ENST00000302509.4:c.1008G>A p.Gly336= p.G336= ENST00000302509 336 ggG/ggA 0 +UNC45A UCSF GRCh37 15 91479194 91479194 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 23 81 0 ENST00000418476.2:c.232G>A p.Glu78Lys p.E78K ENST00000418476 NM_018671.3 78 Gaa/Aaa 0 +UNC45A UCSF GRCh37 15 91486252 91486252 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 59 131 0 ENST00000418476.2:c.967G>A p.Val323Met p.V323M ENST00000418476 NM_018671.3 323 Gtg/Atg 0 +UNC5D UCSF GRCh37 8 35647908 35647908 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 68 150 0 ENST00000404895.2:c.2689C>T p.Pro897Ser p.P897S ENST00000404895 NM_080872.2 897 Cca/Tca 0 +UNC79 UCSF GRCh37 14 94121687 94121687 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 119 72 191 0 ENST00000393151.2:c.6507C>T p.Leu2169= p.L2169= ENST00000393151 2169 ctC/ctT 0 +UNKL UCSF GRCh37 16 1463919 1463919 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 8 9 0 ENST00000389221.4:c.215C>T p.Thr72Ile p.T72I ENST00000389221 NM_001193388.3 72 aCc/aTc 0 +UPF2 UCSF GRCh37 10 12071404 12071404 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 203 79 209 0 ENST00000356352.2:c.485G>A p.Ser162Asn p.S162N ENST00000356352 162 aGc/aAc 0 +UROC1 UCSF GRCh37 3 126211339 126211339 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 21 33 0 ENST00000290868.2:c.1530G>A p.Arg510= p.R510= ENST00000290868 NM_144639.2 510 agG/agA 0 +USH1G UCSF GRCh37 17 72916727 72916727 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 41 70 0 ENST00000319642.1:c.204C>T p.Pro68= p.P68= ENST00000319642 NM_173477.2 68 ccC/ccT 0 +USP14 UCSF GRCh37 18 199201 199201 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 67 164 0 ENST00000261601.7:c.762-1G>A p.X254_splice ENST00000261601 NM_005151.3 0 +USP16 UCSF GRCh37 21 30421082 30421082 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 47 96 0 ENST00000334352.4:c.2012G>A p.Gly671Asp p.G671D ENST00000334352 NM_001032410.1 671 gGt/gAt 0 +USP29 UCSF GRCh37 19 57641558 57641558 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 98 222 0 ENST00000254181.4:c.1515G>A p.Arg505= p.R505= ENST00000254181 NM_020903.2 505 agG/agA 0 +USP31 UCSF GRCh37 16 23083470 23083470 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 39 93 0 ENST00000219689.7:c.2384G>A p.Gly795Asp p.G795D ENST00000219689 NM_020718.3 795 gGc/gAc 0 +USP31 UCSF GRCh37 16 23093858 23093858 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 100 0 ENST00000219689.7:c.1851G>A p.Trp617Ter p.W617* ENST00000219689 NM_020718.3 617 tgG/tgA 0 +USP37 UCSF GRCh37 2 219399332 219399332 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 72 119 0 ENST00000258399.3:c.778G>A p.Gly260Arg p.G260R ENST00000258399 NM_020935.2 260 Ggg/Agg 0 +USP42 UCSF GRCh37 7 6193961 6193961 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 13 22 0 ENST00000306177.5:c.2776G>A p.Asp926Asn p.D926N ENST00000306177 NM_032172.2 926 Gac/Aac 0 +USP49 UCSF GRCh37 6 41773902 41773902 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 54 127 0 ENST00000373009.3:c.820C>T p.Leu274Phe p.L274F ENST00000373009 274 Ctc/Ttc 0 +USP53 UCSF GRCh37 4 120192956 120192956 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 100 201 0 ENST00000274030.6:c.1941G>A p.Lys647= p.K647= ENST00000274030 NM_019050.2 647 aaG/aaA 0 +USP6 UCSF GRCh37 17 5042941 5042941 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 57 105 0 ENST00000250066.6:c.1470C>T p.Thr490= p.T490= ENST00000250066 NM_004505.2 490 acC/acT 0 +USP6 UCSF GRCh37 17 5049340 5049340 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 85 190 0 ENST00000250066.6:c.2190C>T p.Thr730= p.T730= ENST00000250066 NM_004505.2 730 acC/acT 0 +USP6NL UCSF GRCh37 10 11531176 11531176 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 188 97 232 0 ENST00000609104.1:c.589C>T p.Leu197Phe p.L197F ENST00000609104 NM_014688.2 197 Ctc/Ttc 0 +USP7 UCSF GRCh37 16 9017133 9017133 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 67 164 0 ENST00000344836.4:c.322G>A p.Asp108Asn p.D108N ENST00000344836 NM_003470.2 108 Gac/Aac 0 +USP9X UCSF GRCh37 X 41031163 41031163 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 83 67 172 0 ENST00000324545.8:c.3100C>T p.Pro1034Ser p.P1034S ENST00000324545 NM_001039590.2 1034 Cca/Tca 0 +UST UCSF GRCh37 6 149340293 149340293 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 68 171 0 ENST00000367463.4:c.700C>T p.Leu234Phe p.L234F ENST00000367463 NM_005715.2 234 Ctt/Ttt 0 +UTP23 UCSF GRCh37 8 117783700 117783700 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 221 68 168 0 ENST00000309822.2:c.369G>A p.Gln123= p.Q123= ENST00000309822 NM_032334.2 123 caG/caA 0 +UTP6 UCSF GRCh37 17 30207669 30207669 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 90 227 0 ENST00000261708.4:c.890C>T p.Ala297Val p.A297V ENST00000261708 NM_018428.2 297 gCc/gTc 0 +UTRN UCSF GRCh37 6 145157578 145157578 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 73 147 0 ENST00000367545.3:c.9966G>A p.Arg3322= p.R3322= ENST00000367545 NM_007124.2 3322 agG/agA 0 +VANGL1 UCSF GRCh37 1 116226592 116226592 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 45 110 0 ENST00000310260.3:c.974C>T p.Ser325Phe p.S325F ENST00000310260 NM_001172412.1 325 tCc/tTc 0 +VARS2 UCSF GRCh37 6 30890299 30890299 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 70 124 0 ENST00000321897.5:c.2005C>T p.Pro669Ser p.P669S ENST00000321897 669 Cca/Tca 0 +VAV1 UCSF GRCh37 19 6825417 6825417 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 20 40 0 ENST00000602142.1:c.827G>A p.Arg276Lys p.R276K ENST00000602142 NM_005428.3 276 aGg/aAg 0 +VAV2 UCSF GRCh37 9 136648680 136648680 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 27 50 0 ENST00000371850.3:c.1668G>A p.Lys556= p.K556= ENST00000371850 NM_001134398.1 556 aaG/aaA 0 +VAX2 UCSF GRCh37 2 71160028 71160028 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 29 59 0 ENST00000234392.2:c.567C>T p.Gly189= p.G189= ENST00000234392 NM_012476.2 189 ggC/ggT 0 +VCAM1 UCSF GRCh37 1 101194751 101194751 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 92 197 0 ENST00000294728.2:c.1017C>T p.Gly339= p.G339= ENST00000294728 NM_001078.3 339 ggC/ggT 0 +VCAN UCSF GRCh37 5 82817933 82817933 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 110 209 0 ENST00000265077.3:c.3808G>A p.Glu1270Lys p.E1270K ENST00000265077 NM_004385.4 1270 Gaa/Aaa 0 +VCAN UCSF GRCh37 5 82808139 82808139 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 33 56 0 ENST00000265077.3:c.966G>A p.Val322= p.V322= ENST00000265077 NM_004385.4 322 gtG/gtA 0 +VCAN UCSF GRCh37 5 82836478 82836478 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 58 160 0 ENST00000265077.3:c.7656G>A p.Lys2552= p.K2552= ENST00000265077 NM_004385.4 2552 aaG/aaA 0 +VCX UCSF GRCh37 X 7811579 7811579 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 166 24 326 0 ENST00000381059.3:c.143G>A p.Gly48Glu p.G48E ENST00000381059 NM_013452.2 48 gGg/gAg 0 +VEGFB UCSF GRCh37 11 64004961 64004961 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 23 39 0 ENST00000309422.2:c.480C>T p.Pro160= p.P160= ENST00000309422 NM_003377.4 160 ccC/ccT 0 +VGLL4 UCSF GRCh37 3 11606380 11606380 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 21 23 0 ENST00000273038.3:c.368C>T p.Ser123Phe p.S123F ENST00000273038 NM_014667.2 123 tCc/tTc 0 +VHL UCSF GRCh37 3 10183713 10183713 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 12 5 13 0 ENST00000256474.2:c.182C>T p.Pro61Leu p.P61L ENST00000256474 NM_000551.3 61 cCc/cTc 0 +VIL1 UCSF GRCh37 2 219290394 219290394 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 47 100 0 ENST00000248444.5:c.207C>T p.Asp69= p.D69= ENST00000248444 NM_007127.2 69 gaC/gaT 0 +VOPP1 UCSF GRCh37 7 55588814 55588814 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 52 105 0 ENST00000285279.5:c.64G>A p.Ala22Thr p.A22T ENST00000285279 NM_030796.3 22 Gcc/Acc 0 +VPRBP UCSF GRCh37 3 51457206 51457206 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 117 191 0 ENST00000423656.1:c.1931G>A p.Arg644Lys p.R644K ENST00000423656 644 aGg/aAg 0 +VPS13A UCSF GRCh37 9 79897163 79897163 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 137 81 145 0 ENST00000360280.3:c.3091G>A p.Asp1031Asn p.D1031N ENST00000360280 NM_033305.2 1031 Gac/Aac 0 +VPS13B UCSF GRCh37 8 100887721 100887721 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 295 106 158 0 ENST00000358544.2:c.11896C>T p.His3966Tyr p.H3966Y ENST00000358544 NM_017890.4 3966 Cac/Tac 0 +VPS13B UCSF GRCh37 8 100880671 100880671 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 28 56 0 ENST00000358544.2:c.11445G>A p.Glu3815= p.E3815= ENST00000358544 NM_017890.4 3815 gaG/gaA 0 +VPS13C UCSF GRCh37 15 62223314 62223314 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 90 176 0 ENST00000261517.5:c.6013G>A p.Glu2005Lys p.E2005K ENST00000261517 NM_020821.2 2005 Gaa/Aaa 0 +VPS13C UCSF GRCh37 15 62302748 62302748 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 83 153 0 ENST00000261517.5:c.934G>A p.Glu312Lys p.E312K ENST00000261517 NM_020821.2 312 Gaa/Aaa 0 +VPS13D UCSF GRCh37 1 12336919 12336919 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 96 178 0 ENST00000358136.3:c.3274C>T p.Pro1092Ser p.P1092S ENST00000358136 NM_015378.2 1092 Cca/Tca 0 +VPS13D UCSF GRCh37 1 12364596 12364596 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 39 80 0 ENST00000358136.3:c.6250C>T p.Pro2084Ser p.P2084S ENST00000358136 NM_015378.2 2084 Ccc/Tcc 0 +VPS13D UCSF GRCh37 1 12343695 12343695 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 67 144 0 ENST00000358136.3:c.5536C>T p.Leu1846= p.L1846= ENST00000358136 NM_015378.2 1846 Ctg/Ttg 0 +VPS18 UCSF GRCh37 15 41192761 41192761 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 135 92 98 0 ENST00000220509.5:c.1745C>T p.Ala582Val p.A582V ENST00000220509 NM_020857.2 582 gCc/gTc 0 +VPS33A UCSF GRCh37 12 122735630 122735630 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 38 99 0 ENST00000267199.4:c.500G>A p.Gly167Asp p.G167D ENST00000267199 NM_022916.4 167 gGt/gAt 0 +VPS33B UCSF GRCh37 15 91548327 91548327 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 49 100 0 ENST00000333371.3:c.1128C>T p.Ile376= p.I376= ENST00000333371 NM_018668.3 376 atC/atT 0 +VPS35 UCSF GRCh37 16 46695702 46695702 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 91 148 0 ENST00000299138.7:c.2139C>T p.Pro713= p.P713= ENST00000299138 NM_018206.4 713 ccC/ccT 0 +VTI1B UCSF GRCh37 14 68120170 68120170 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.00092 P10_Rec Untested WXS Illumina HiSeq 42 33 76 0 ENST00000554659.1:c.586C>T p.Arg196Cys p.R196C ENST00000554659 NM_006370.2 196 Cgt/Tgt 0 +VWA5A UCSF GRCh37 11 123989046 123989046 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 67 130 0 ENST00000392748.1:c.397C>T p.Leu133= p.L133= ENST00000392748 NM_014622.4 133 Ctg/Ttg 0 +VWA5B2 UCSF GRCh37 3 183955045 183955045 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 46 81 0 ENST00000426955.2:c.1565C>T p.Pro522Leu p.P522L ENST00000426955 NM_138345.1 522 cCt/cTt 0 +VWCE UCSF GRCh37 11 61048580 61048580 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 14 26 0 ENST00000335613.5:c.915G>A p.Gly305= p.G305= ENST00000335613 NM_152718.2 305 ggG/ggA 0 +VWDE UCSF GRCh37 7 12381735 12381735 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 27 66 0 ENST00000275358.3:c.4220C>T p.Pro1407Leu p.P1407L ENST00000275358 NM_001135924.1 1407 cCa/cTa 0 +VWDE UCSF GRCh37 7 12428924 12428924 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 58 112 0 ENST00000275358.3:c.304C>T p.Pro102Ser p.P102S ENST00000275358 NM_001135924.1 102 Cca/Tca 0 +VWDE UCSF GRCh37 7 12410335 12410335 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 45 143 0 ENST00000275358.3:c.1743G>A p.Gly581= p.G581= ENST00000275358 NM_001135924.1 581 ggG/ggA 0 +VWF UCSF GRCh37 12 6125351 6125351 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 50 151 0 ENST00000261405.5:c.5359G>A p.Gly1787Ser p.G1787S ENST00000261405 NM_000552.3 1787 Ggt/Agt 0 +VWF UCSF GRCh37 12 6101071 6101071 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 46 79 0 ENST00000261405.5:c.6712C>T p.Pro2238Ser p.P2238S ENST00000261405 NM_000552.3 2238 Cct/Tct 0 +WAPAL UCSF GRCh37 10 88206137 88206137 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 74 139 0 ENST00000298767.5:c.3184C>T p.Pro1062Ser p.P1062S ENST00000298767 NM_015045.2 1062 Ccc/Tcc 0 +WARS UCSF GRCh37 14 100820200 100820200 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 54 83 0 ENST00000355338.2:c.549C>T p.Leu183= p.L183= ENST00000355338 NM_173701.1 183 ctC/ctT 0 +WASL UCSF GRCh37 7 123332789 123332789 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 65 79 0 ENST00000223023.4:c.959C>T p.Ala320Val p.A320V ENST00000223023 NM_003941.3 320 gCt/gTt 0 +WBSCR27 UCSF GRCh37 7 73256395 73256395 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 30 49 1 ENST00000297873.4:c.76G>A p.Ala26Thr p.A26T ENST00000297873 NM_152559.2 26 Gcc/Acc 0 +WDFY4 UCSF GRCh37 10 50184901 50184901 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 23 39 0 ENST00000325239.5:c.9168C>T p.Pro3056= p.P3056= ENST00000325239 NM_020945.1 3056 ccC/ccT 0 +WDR1 UCSF GRCh37 4 10086084 10086084 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 87 146 0 ENST00000382452.2:c.1022G>A p.Ser341Asn p.S341N ENST00000382452 NM_017491.3 341 aGc/aAc 0 +WDR1 UCSF GRCh37 4 10084717 10084717 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 45 80 0 ENST00000382452.2:c.1125G>A p.Glu375= p.E375= ENST00000382452 NM_017491.3 375 gaG/gaA 0 +WDR19 UCSF GRCh37 4 39217716 39217716 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 133 206 0 ENST00000399820.3:c.1135G>A p.Glu379Lys p.E379K ENST00000399820 NM_025132.3 379 Gag/Aag 0 +WDR41 UCSF GRCh37 5 76754933 76754933 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 89 162 0 ENST00000296679.4:c.365C>T p.Thr122Ile p.T122I ENST00000296679 NM_018268.2 122 aCt/aTt 0 +WDR52 UCSF GRCh37 3 113022845 113022845 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 91 206 0 ENST00000393845.2:c.4995G>A p.Lys1665= p.K1665= ENST00000393845 NM_001164496.1 1665 aaG/aaA 0 +WDR60 UCSF GRCh37 7 158672454 158672454 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 68 180 0 ENST00000407559.3:c.653C>T p.Pro218Leu p.P218L ENST00000407559 NM_018051.4 218 cCc/cTc 0 +WDR64 UCSF GRCh37 1 241842826 241842826 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 117 107 213 0 ENST00000366552.2:c.523C>T p.Leu175= p.L175= ENST00000366552 NM_144625.4 175 Ctg/Ttg 0 +WDR64 UCSF GRCh37 1 241901791 241901791 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 42 106 0 ENST00000366552.2:c.1291G>A p.Gly431Arg p.G431R ENST00000366552 NM_144625.4 431 Gga/Aga 0 +WDR67 UCSF GRCh37 8 124109547 124109547 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 249 71 176 0 ENST00000287380.1:c.697G>A p.Gly233Ser p.G233S ENST00000287380 NM_145647.3 233 Ggc/Agc 0 +WDR78 UCSF GRCh37 1 67293571 67293571 + missense_variant Missense_Mutation SNP C C T snp132_rs78356162 P10_Rec Untested WXS Illumina HiSeq 100 56 222 0 ENST00000371026.3:c.2036G>A p.Gly679Asp p.G679D ENST00000371026 NM_024763.4 679 gGc/gAc 0 +WDR87 UCSF GRCh37 19 38375629 38375629 + synonymous_variant Silent SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 76 51 144 0 ENST00000303868.5:c.8565T>C p.Pro2855= p.P2855= ENST00000303868 NM_031951.3 2855 ccT/ccC 0 +WDR90 UCSF GRCh37 16 708958 708958 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 70 90 0 ENST00000293879.4:c.2958C>T p.Val986= p.V986= ENST00000293879 986 gtC/gtT 0 +WDR93 UCSF GRCh37 15 90280885 90280885 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 64 145 0 ENST00000268130.7:c.1690G>A p.Gly564Arg p.G564R ENST00000268130 NM_020212.1 564 Gga/Aga 0 +WDYHV1 UCSF GRCh37 8 124453573 124453573 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 70 24 45 0 ENST00000287387.2:c.536T>C p.Ile179Thr p.I179T ENST00000287387 NM_018024.1 179 aTc/aCc 0 +WFDC8 UCSF GRCh37 20 44190858 44190858 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 47 92 0 ENST00000289953.2:c.27G>A p.Gly9= p.G9= ENST00000289953 NM_130896.2 9 ggG/ggA 0 +WFS1 UCSF GRCh37 4 6303446 6303446 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 75 147 0 ENST00000226760.1:c.1924G>A p.Ala642Thr p.A642T ENST00000226760 NM_001145853.1 642 Gcc/Acc 0 +WHSC2 UCSF GRCh37 4 1993350 1993350 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 69 152 0 ENST00000411638.2:c.303G>A p.Pro101= p.P101= ENST00000411638 NM_005663.4 101 ccG/ccA 0 +WIPF3 UCSF GRCh37 7 29874428 29874428 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 31 64 0 ENST00000242140.5:c.88C>T p.Pro30Ser p.P30S ENST00000242140 30 Ccg/Tcg 0 +WIPI1 UCSF GRCh37 17 66426297 66426297 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 60 95 0 ENST00000262139.5:c.805C>T p.Pro269Ser p.P269S ENST00000262139 NM_017983.5 269 Cca/Tca 0 +WISP2 UCSF GRCh37 20 43348583 43348583 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 17 30 0 ENST00000190983.4:c.106C>T p.Pro36Ser p.P36S ENST00000190983 NM_003881.2 36 Cct/Tct 0 +WISP3 UCSF GRCh37 6 112386099 112386099 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 100 212 0 ENST00000230529.5:c.488G>A p.Ser163Asn p.S163N ENST00000230529 NM_003880.3 163 aGt/aAt 0 +WIZ UCSF GRCh37 19 15558993 15558993 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 61 114 0 ENST00000263381.7:c.126C>T p.Gly42= p.G42= ENST00000263381 NM_021241.2 42 ggC/ggT 0 +WNK4 UCSF GRCh37 17 40939296 40939296 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 33 66 0 ENST00000246914.5:c.1477G>A p.Val493Met p.V493M ENST00000246914 NM_032387.4 493 Gtg/Atg 0 +WWOX UCSF GRCh37 16 78148914 78148914 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 68 179 0 ENST00000566780.1:c.272C>T p.Ala91Val p.A91V ENST00000566780 NM_016373.2 91 gCg/gTg 0 +XCL2 UCSF GRCh37 1 168510241 168510241 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 49 155 0 ENST00000367819.2:c.294G>A p.Lys98= p.K98= ENST00000367819 NM_003175.3 98 aaG/aaA 0 +XIRP1 UCSF GRCh37 3 39225432 39225432 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 1 27 39 0 ENST00000340369.3:c.5505C>T p.Cys1835= p.C1835= ENST00000340369 NM_194293.2 1835 tgC/tgT 0 +XIRP2 UCSF GRCh37 2 168104383 168104383 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 64 159 0 ENST00000409195.1:c.6481C>T p.Pro2161Ser p.P2161S ENST00000409195 NM_152381.5 2161 Ccc/Tcc 0 +XIRP2 UCSF GRCh37 2 168106448 168106448 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 120 84 201 0 ENST00000409195.1:c.8546C>T p.Ala2849Val p.A2849V ENST00000409195 NM_152381.5 2849 gCa/gTa 0 +XKR6 UCSF GRCh37 8 10755681 10755681 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 49 100 0 ENST00000416569.2:c.1707G>A p.Gly569= p.G569= ENST00000416569 NM_173683.3 569 ggG/ggA 0 +XPO6 UCSF GRCh37 16 28133067 28133067 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 66 99 0 ENST00000304658.5:c.1783C>T p.Leu595= p.L595= ENST00000304658 NM_015171.3 595 Ctg/Ttg 0 +XPO6 UCSF GRCh37 16 28187408 28187408 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 52 107 0 ENST00000304658.5:c.216C>T p.Ile72= p.I72= ENST00000304658 NM_015171.3 72 atC/atT 0 +XPO7 UCSF GRCh37 8 21840150 21840150 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 90 173 0 ENST00000252512.9:c.1105-1G>A p.X369_splice ENST00000252512 NM_015024.4 0 +XRCC5 UCSF GRCh37 2 217024854 217024854 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 57 128 0 ENST00000392132.2:c.1734C>T p.Val578= p.V578= ENST00000392132 NM_021141.3 578 gtC/gtT 0 +XRN2 UCSF GRCh37 20 21306968 21306968 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 69 125 0 ENST00000377191.3:c.127C>T p.Pro43Ser p.P43S ENST00000377191 NM_012255.3 43 Cca/Tca 0 +YEATS2 UCSF GRCh37 3 183524881 183524881 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 29 78 0 ENST00000305135.5:c.4011+1G>A p.X1337_splice ENST00000305135 NM_018023.4 0 +YIPF1 UCSF GRCh37 1 54332585 54332585 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 51 124 0 ENST00000072644.1:c.494C>T p.Ala165Val p.A165V ENST00000072644 NM_018982.4 165 gCt/gTt 0 +YIPF7 UCSF GRCh37 4 44626798 44626798 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 28 48 0 ENST00000332990.5:c.500C>T p.Ala167Val p.A167V ENST00000332990 NM_182592.2 167 gCa/gTa 0 +YLPM1 UCSF GRCh37 14 75248373 75248373 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 58 126 0 ENST00000325680.7:c.1627C>T p.Pro543Ser p.P543S ENST00000325680 NM_019589.2 543 Cca/Tca 0 +YTHDC2 UCSF GRCh37 5 112868676 112868676 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 61 147 0 ENST00000161863.4:c.776G>A p.Arg259Lys p.R259K ENST00000161863 NM_022828.3 259 aGa/aAa 0 +YTHDF1 UCSF GRCh37 20 61834707 61834707 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.014,1000g2011may_all_0.0485,snp132_rs115419512 P10_Rec Untested WXS Illumina HiSeq 51 52 75 0 ENST00000370339.3:c.585C>T p.Val195= p.V195= ENST00000370339 NM_017798.3 195 gtC/gtT 0 +YTHDF2 UCSF GRCh37 1 29069104 29069104 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 130 199 0 ENST00000373812.3:c.322C>T p.Pro108Ser p.P108S ENST00000373812 NM_016258.2 108 Cca/Tca 0 +ZBBX UCSF GRCh37 3 167086299 167086299 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 63 146 0 ENST00000392766.2:c.132G>A p.Lys44= p.K44= ENST00000392766 NM_001199201.1 44 aaG/aaA 0 +ZBED4 UCSF GRCh37 22 50278966 50278966 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 124 193 0 ENST00000216268.5:c.1656G>A p.Met552Ile p.M552I ENST00000216268 NM_014838.2 552 atG/atA 0 +ZBTB44 UCSF GRCh37 11 130131626 130131626 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 129 93 206 0 ENST00000357899.4:c.143T>C p.Val48Ala p.V48A ENST00000357899 48 gTa/gCa 0 +ZC3H11A UCSF GRCh37 1 203819029 203819029 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 70 146 0 ENST00000332127.4:c.1814C>T p.Thr605Ile p.T605I ENST00000332127 605 aCa/aTa 0 +ZC3H12B UCSF GRCh37 X 64721891 64721891 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 78 150 0 ENST00000338957.4:c.1313C>T p.Pro438Leu p.P438L ENST00000338957 NM_001010888.3 438 cCc/cTc 0 +ZC3H12D UCSF GRCh37 6 149795470 149795470 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 18 65 0 ENST00000409806.3:c.210C>T p.Ala70= p.A70= ENST00000409806 70 gcC/gcT 0 +ZC3H18 UCSF GRCh37 16 88666340 88666340 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 60 118 0 ENST00000301011.5:c.1072G>A p.Asp358Asn p.D358N ENST00000301011 NM_144604.3 358 Gat/Aat 0 +ZC3H4 UCSF GRCh37 19 47570075 47570075 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 7 21 0 ENST00000253048.5:c.3450C>T p.Asp1150= p.D1150= ENST00000253048 NM_015168.1 1150 gaC/gaT 0 +ZCCHC17 UCSF GRCh37 1 31819541 31819541 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 53 119 0 ENST00000344147.5:c.372C>T p.Thr124= p.T124= ENST00000344147 NM_016505.2 124 acC/acT 0 +ZCCHC4 UCSF GRCh37 4 25334924 25334924 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 60 156 0 ENST00000302874.4:c.449C>T p.Ser150Phe p.S150F ENST00000302874 NM_024936.2 150 tCc/tTc 0 +ZCCHC7 UCSF GRCh37 9 37357113 37357113 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 58 152 0 ENST00000336755.5:c.1480C>T p.Pro494Ser p.P494S ENST00000336755 NM_032226.2 494 Ccc/Tcc 0 +ZDBF2 UCSF GRCh37 2 207172904 207172904 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 143 118 242 0 ENST00000374423.3:c.3652G>A p.Val1218Ile p.V1218I ENST00000374423 NM_020923.1 1218 Gtt/Att 0 +ZDBF2 UCSF GRCh37 2 207146624 207146624 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 64 140 0 ENST00000374423.3:c.51C>T p.Asn17= p.N17= ENST00000374423 NM_020923.1 17 aaC/aaT 0 +ZDHHC11 UCSF GRCh37 5 837480 837480 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 245 85 294 0 ENST00000283441.8:c.900G>A p.Gln300= p.Q300= ENST00000283441 NM_024786.2 300 caG/caA 0 +ZDHHC18 UCSF GRCh37 1 27177632 27177632 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 47 122 0 ENST00000374142.4:c.846G>A p.Leu282= p.L282= ENST00000374142 NM_032283.2 282 ttG/ttA 0 +ZEB1 UCSF GRCh37 10 31810044 31810044 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 73 138 0 ENST00000320985.10:c.1781C>T p.Ser594Phe p.S594F ENST00000320985 594 tCt/tTt 0 +ZEB1 UCSF GRCh37 10 31809528 31809528 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 168 69 127 0 ENST00000320985.10:c.1265G>A p.Gly422Asp p.G422D ENST00000320985 422 gGt/gAt 0 +ZFAT UCSF GRCh37 8 135602547 135602547 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 338 87 166 0 ENST00000377838.3:c.2527C>T p.Arg843Ter p.R843* ENST00000377838 NM_020863.3 843 Cga/Tga 0 +ZFHX3 UCSF GRCh37 16 72821844 72821844 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 65 114 0 ENST00000268489.5:c.10331C>T p.Ala3444Val p.A3444V ENST00000268489 NM_006885.3 3444 gCa/gTa 0 +ZFHX3 UCSF GRCh37 16 72822098 72822098 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 33 57 0 ENST00000268489.5:c.10077C>T p.Ser3359= p.S3359= ENST00000268489 NM_006885.3 3359 tcC/tcT 0 +ZFP106 UCSF GRCh37 15 42742112 42742112 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 114 191 0 ENST00000263805.4:c.2289C>T p.His763= p.H763= ENST00000263805 NM_022473.1 763 caC/caT 0 +ZFP112 UCSF GRCh37 19 44833062 44833062 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 103 180 0 ENST00000337401.4:c.1266G>A p.Lys422= p.K422= ENST00000337401 NM_001083335.1 422 aaG/aaA 0 +ZFP37 UCSF GRCh37 9 115805440 115805440 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 138 68 163 0 ENST00000374227.3:c.1458G>A p.Glu486= p.E486= ENST00000374227 486 gaG/gaA 0 +ZFP64 UCSF GRCh37 20 50701786 50701786 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 23 59 0 ENST00000361387.2:c.1248C>T p.Cys416= p.C416= ENST00000361387 NM_199427.2 416 tgC/tgT 0 +ZFR2 UCSF GRCh37 19 3819067 3819067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 10 32 0 ENST00000262961.4:c.1907G>A p.Arg636Gln p.R636Q ENST00000262961 NM_015174.1 636 cGa/cAa 0 +ZFR2 UCSF GRCh37 19 3819223 3819223 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 6 26 0 ENST00000262961.4:c.1751G>A p.Arg584Gln p.R584Q ENST00000262961 NM_015174.1 584 cGg/cAg 0 +ZFYVE1 UCSF GRCh37 14 73437702 73437702 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 56 103 1 ENST00000556143.1:c.2222G>A p.Gly741Glu p.G741E ENST00000556143 NM_021260.2 741 gGa/gAa 0 +ZFYVE1 UCSF GRCh37 14 73490913 73490913 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 96 208 0 ENST00000556143.1:c.304G>A p.Glu102Lys p.E102K ENST00000556143 NM_021260.2 102 Gag/Aag 0 +ZMYM1 UCSF GRCh37 1 35559671 35559671 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 39 138 0 ENST00000359858.4:c.83C>T p.Pro28Leu p.P28L ENST00000359858 NM_024772.3 28 cCc/cTc 0 +ZMYND11 UCSF GRCh37 10 255829 255829 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 191 69 167 0 ENST00000381591.1:c.117G>A p.Lys39= p.K39= ENST00000381591 39 aaG/aaA 0 +ZNF131 UCSF GRCh37 5 43139398 43139398 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 86 177 0 ENST00000509156.1:c.358G>A p.Ala120Thr p.A120T ENST00000509156 120 Gcc/Acc 0 +ZNF142 UCSF GRCh37 2 219513823 219513823 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 48 88 0 ENST00000411696.2:c.808G>A p.Glu270Lys p.E270K ENST00000411696 270 Gag/Aag 0 +ZNF16 UCSF GRCh37 8 146157636 146157636 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 389 101 194 0 ENST00000276816.4:c.537G>A p.Arg179= p.R179= ENST00000276816 NM_001029976.2 179 agG/agA 0 +ZNF165 UCSF GRCh37 6 28056718 28056718 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 43 119 0 ENST00000377325.1:c.928C>T p.His310Tyr p.H310Y ENST00000377325 NM_003447.3 310 Cat/Tat 0 +ZNF184 UCSF GRCh37 6 27420104 27420104 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 62 173 0 ENST00000211936.6:c.1234C>T p.His412Tyr p.H412Y ENST00000211936 NM_007149.2 412 Cat/Tat 0 +ZNF187 UCSF GRCh37 6 28244609 28244609 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 93 225 0 ENST00000421553.2:n.1443C>T *481* ENST00000421553 0 +ZNF224 UCSF GRCh37 19 44611321 44611321 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0011 P10_Rec Untested WXS Illumina HiSeq 164 136 255 0 ENST00000336976.6:c.1008G>A p.Met336Ile p.M336I ENST00000336976 NM_013398.2 336 atG/atA 0 +ZNF259 UCSF GRCh37 11 116650508 116650508 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 49 146 0 ENST00000227322.3:c.1225G>A p.Ala409Thr p.A409T ENST00000227322 NM_003904.3 409 Gca/Aca 0 +ZNF280C UCSF GRCh37 X 129339294 129339294 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 73 155 1 ENST00000370978.4:c.2138C>T p.Thr713Ile p.T713I ENST00000370978 NM_017666.4 713 aCt/aTt 0 +ZNF281 UCSF GRCh37 1 200377972 200377972 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 134 191 0 ENST00000294740.3:c.862C>T p.Pro288Ser p.P288S ENST00000294740 NM_001281293.1 288 Cct/Tct 0 +ZNF282 UCSF GRCh37 7 148907734 148907734 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 13 28 0 ENST00000262085.3:c.890C>T p.Thr297Ile p.T297I ENST00000262085 NM_003575.2 297 aCc/aTc 0 +ZNF3 UCSF GRCh37 7 99669573 99669573 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 103 206 0 ENST00000299667.4:c.534G>A p.Gly178= p.G178= ENST00000299667 178 ggG/ggA 0 +ZNF300 UCSF GRCh37 5 150275333 150275333 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 58 154 0 ENST00000274599.5:c.1468G>A p.Glu490Lys p.E490K ENST00000274599 NM_052860.2 490 Gaa/Aaa 0 +ZNF317 UCSF GRCh37 19 9269574 9269574 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 37 96 0 ENST00000247956.6:c.458G>A p.Gly153Asp p.G153D ENST00000247956 NM_020933.4 153 gGt/gAt 0 +ZNF324B UCSF GRCh37 19 58966831 58966831 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 49 91 0 ENST00000336614.4:c.520C>T p.Pro174Ser p.P174S ENST00000336614 NM_207395.2 174 Ccc/Tcc 0 +ZNF385A UCSF GRCh37 12 54764711 54764711 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 64 117 0 ENST00000338010.5:c.834G>A p.Gln278= p.Q278= ENST00000338010 NM_001130967.1 278 caG/caA 0 +ZNF410 UCSF GRCh37 14 74388848 74388848 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 64 116 0 ENST00000555044.1:c.1209C>T p.Pro403= p.P403= ENST00000555044 NM_021188.2 403 ccC/ccT 0 +ZNF415 UCSF GRCh37 19 53619578 53619578 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 148 116 251 0 ENST00000500065.4:c.124C>T p.Leu42= p.L42= ENST00000500065 NM_001136038.2 42 Ctg/Ttg 0 +ZNF423 UCSF GRCh37 16 49669888 49669888 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 24 56 0 ENST00000262383.2:c.3175G>A p.Gly1059Arg p.G1059R ENST00000262383 1059 Ggg/Agg 0 +ZNF425 UCSF GRCh37 7 148815372 148815372 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 121 177 0 ENST00000378061.2:c.87G>A p.Trp29Ter p.W29* ENST00000378061 NM_001001661.2 29 tgG/tgA 0 +ZNF429 UCSF GRCh37 19 21719844 21719844 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 106 213 0 ENST00000358491.4:c.989G>A p.Ser330Asn p.S330N ENST00000358491 NM_001001415.2 330 aGc/aAc 0 +ZNF43 UCSF GRCh37 19 21990809 21990809 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 129 104 208 0 ENST00000354959.4:c.2030C>T p.Pro677Leu p.P677L ENST00000354959 NM_003423.3 677 cCc/cTc 0 +ZNF432 UCSF GRCh37 19 52537701 52537701 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 112 99 235 0 ENST00000221315.5:c.1231C>T p.Pro411Ser p.P411S ENST00000221315 NM_014650.2 411 Ccc/Tcc 0 +ZNF445 UCSF GRCh37 3 44489299 44489299 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 106 185 0 ENST00000396077.2:c.1864G>A p.Glu622Lys p.E622K ENST00000396077 NM_181489.5 622 Gag/Aag 0 +ZNF449 UCSF GRCh37 X 134481311 134481311 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 64 176 0 ENST00000339249.4:c.268G>A p.Val90Met p.V90M ENST00000339249 NM_152695.5 90 Gtg/Atg 0 +ZNF460 UCSF GRCh37 19 57795929 57795929 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 66 195 0 ENST00000360338.3:c.41C>T p.Thr14Ile p.T14I ENST00000360338 NM_006635.3 14 aCc/aTc 0 +ZNF470 UCSF GRCh37 19 57089633 57089633 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 62 130 0 ENST00000330619.8:c.1836G>A p.Gln612= p.Q612= ENST00000330619 NM_001001668.3 612 caG/caA 0 +ZNF483 UCSF GRCh37 9 114304687 114304687 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 144 57 129 0 ENST00000309235.5:c.1472G>A p.Gly491Glu p.G491E ENST00000309235 NM_133464.2 491 gGa/gAa 0 +ZNF484 UCSF GRCh37 9 95610568 95610568 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 240 111 209 0 ENST00000375495.3:c.501C>T p.His167= p.H167= ENST00000375495 NM_031486.2 167 caC/caT 0 +ZNF516 UCSF GRCh37 18 74091782 74091782 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 39 65 1 ENST00000443185.2:c.2288C>T p.Pro763Leu p.P763L ENST00000443185 NM_014643.3 763 cCt/cTt 0 +ZNF527 UCSF GRCh37 19 37880574 37880574 + synonymous_variant Silent SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 71 79 132 0 ENST00000436120.2:c.1623T>C p.Leu541= p.L541= ENST00000436120 NM_032453.1 541 ctT/ctC 0 +ZNF541 UCSF GRCh37 19 48058965 48058965 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 38 49 79 0 ENST00000391901.3:c.149G>A p.Ser50Asn p.S50N ENST00000391901 NM_001277075.1 50 aGt/aAt 0 +ZNF543 UCSF GRCh37 19 57839758 57839758 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 77 205 0 ENST00000321545.4:c.928C>T p.Pro310Ser p.P310S ENST00000321545 NM_213598.3 310 Ccc/Tcc 0 +ZNF543 UCSF GRCh37 19 57840242 57840242 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 95 154 0 ENST00000321545.4:c.1412G>A p.Ser471Asn p.S471N ENST00000321545 NM_213598.3 471 aGc/aAc 0 +ZNF547 UCSF GRCh37 19 57888578 57888578 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 61 154 0 ENST00000282282.3:c.234G>A p.Lys78= p.K78= ENST00000282282 NM_173631.2 78 aaG/aaA 0 +ZNF554 UCSF GRCh37 19 2834661 2834661 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 86 145 0 ENST00000317243.5:c.1428G>A p.Arg476= p.R476= ENST00000317243 NM_001102651.1 476 agG/agA 0 +ZNF578 UCSF GRCh37 19 53014224 53014224 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 102 234 0 ENST00000421239.2:c.590C>T p.Ser197Phe p.S197F ENST00000421239 NM_001099694.1 197 tCt/tTt 0 +ZNF582 UCSF GRCh37 19 56895688 56895688 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 82 204 0 ENST00000301310.4:c.1098C>T p.Pro366= p.P366= ENST00000301310 NM_144690.1 366 ccC/ccT 0 +ZNF585A UCSF GRCh37 19 37643323 37643323 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 81 181 0 ENST00000292841.5:c.1313C>T p.Ser438Phe p.S438F ENST00000292841 NM_152655.2 438 tCt/tTt 0 +ZNF585B UCSF GRCh37 19 37677780 37677780 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 93 180 0 ENST00000532828.2:c.659G>A p.Gly220Glu p.G220E ENST00000532828 NM_152279.3 220 gGg/gAg 0 +ZNF592 UCSF GRCh37 15 85326624 85326624 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 113 84 177 0 ENST00000299927.3:c.718G>A p.Glu240Lys p.E240K ENST00000299927 240 Gaa/Aaa 0 +ZNF598 UCSF GRCh37 16 2049509 2049509 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 19 0 ENST00000431526.1:c.2041C>T p.Pro681Ser p.P681S ENST00000431526 681 Ccg/Tcg 0 +ZNF607 UCSF GRCh37 19 38189934 38189934 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 130 87 192 0 ENST00000355202.4:c.1098G>A p.Lys366= p.K366= ENST00000355202 NM_032689.4 366 aaG/aaA 0 +ZNF609 UCSF GRCh37 15 64973532 64973532 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 130 96 205 0 ENST00000326648.3:c.4187C>T p.Ala1396Val p.A1396V ENST00000326648 NM_015042.1 1396 gCc/gTc 0 +ZNF609 UCSF GRCh37 15 64967741 64967741 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 67 186 0 ENST00000326648.3:c.2688G>A p.Glu896= p.E896= ENST00000326648 NM_015042.1 896 gaG/gaA 0 +ZNF622 UCSF GRCh37 5 16465647 16465647 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 43 97 0 ENST00000308683.2:c.128C>T p.Thr43Ile p.T43I ENST00000308683 NM_033414.2 43 aCc/aTc 0 +ZNF623 UCSF GRCh37 8 144733633 144733633 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 264 60 116 0 ENST00000501748.2:c.1591G>A p.Glu531Lys p.E531K ENST00000501748 NM_014789.3 531 Gaa/Aaa 0 +ZNF623 UCSF GRCh37 8 144732450 144732450 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.309,1000g2011may_all_0.3611,snp132_rs3750204 P10_Rec Untested WXS Illumina HiSeq 352 85 183 0 ENST00000501748.2:c.408G>A p.Ser136= p.S136= ENST00000501748 NM_014789.3 136 tcG/tcA 0 +ZNF627 UCSF GRCh37 19 11727672 11727672 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 141 103 223 0 ENST00000361113.5:c.354G>A p.Arg118= p.R118= ENST00000361113 NM_145295.3 118 agG/agA 0 +ZNF639 UCSF GRCh37 3 179051833 179051833 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 116 206 0 ENST00000326361.3:c.1081C>T p.Leu361Phe p.L361F ENST00000326361 NM_016331.1 361 Ctc/Ttc 0 +ZNF645 UCSF GRCh37 X 22291520 22291520 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 89 183 0 ENST00000323684.1:c.412C>T p.His138Tyr p.H138Y ENST00000323684 NM_152577.3 138 Cat/Tat 0 +ZNF658 UCSF GRCh37 9 40773158 40773158 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 223 127 241 0 ENST00000602553.1:c.2117G>A p.Arg706Lys p.R706K ENST00000602553 706 aGa/aAa 0 +ZNF665 UCSF GRCh37 19 53668410 53668410 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 124 233 0 ENST00000600412.1:c.1138C>T p.Leu380= p.L380= ENST00000600412 380 Cta/Tta 0 +ZNF668 UCSF GRCh37 16 31075243 31075243 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 9 23 0 ENST00000394983.2:c.538C>T p.Pro180Ser p.P180S ENST00000394983 180 Cct/Tct 0 +ZNF668 UCSF GRCh37 16 31075703 31075703 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 33 94 0 ENST00000394983.2:c.78C>T p.Ser26= p.S26= ENST00000394983 26 tcC/tcT 0 +ZNF700 UCSF GRCh37 19 12060846 12060846 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 119 197 0 ENST00000254321.5:c.2007G>A p.Lys669= p.K669= ENST00000254321 NM_144566.2 669 aaG/aaA 0 +ZNF711 UCSF GRCh37 X 84526171 84526171 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 51 133 0 ENST00000276123.3:c.1623G>A p.Arg541= p.R541= ENST00000276123 541 agG/agA 0 +ZNF749 UCSF GRCh37 19 57953330 57953330 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 120 207 0 ENST00000334181.4:c.93C>T p.His31= p.H31= ENST00000334181 NM_001023561.2 31 caC/caT 0 +ZNF750 UCSF GRCh37 17 80789491 80789491 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 62 124 0 ENST00000269394.3:c.840C>T p.Asp280= p.D280= ENST00000269394 NM_024702.2 280 gaC/gaT 0 +ZNF76 UCSF GRCh37 6 35255438 35255438 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 51 113 0 ENST00000373953.3:c.248G>A p.Ser83Asn p.S83N ENST00000373953 NM_003427.3 83 aGc/aAc 0 +ZNF761 UCSF GRCh37 19 53958841 53958841 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 149 128 221 0 ENST00000454407.1:n.1533C>T *511* ENST00000454407 0 +ZNF764 UCSF GRCh37 16 30569472 30569472 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 15 23 0 ENST00000252797.2:c.32G>A p.Arg11Gln p.R11Q ENST00000252797 NM_033410.3 11 cGg/cAg 0 +ZNF766 UCSF GRCh37 19 52793879 52793879 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 93 195 0 ENST00000439461.1:c.835G>A p.Val279Ile p.V279I ENST00000439461 NM_001010851.2 279 Gtc/Atc 0 +ZNF770 UCSF GRCh37 15 35273889 35273889 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 101 221 0 ENST00000356321.4:c.1747G>A p.Glu583Lys p.E583K ENST00000356321 NM_014106.3 583 Gag/Aag 0 +ZNF770 UCSF GRCh37 15 35274604 35274604 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 28 94 0 ENST00000356321.4:c.1032G>A p.Lys344= p.K344= ENST00000356321 NM_014106.3 344 aaG/aaA 0 +ZNF777 UCSF GRCh37 7 149129924 149129924 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 21 26 0 ENST00000247930.4:c.1439G>A p.Gly480Glu p.G480E ENST00000247930 NM_015694.2 480 gGg/gAg 0 +ZNF777 UCSF GRCh37 7 149153033 149153033 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 61 128 0 ENST00000247930.4:c.81C>T p.Leu27= p.L27= ENST00000247930 NM_015694.2 27 ctC/ctT 0 +ZNF804A UCSF GRCh37 2 185803266 185803266 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 103 190 0 ENST00000302277.6:c.3143C>T p.Pro1048Leu p.P1048L ENST00000302277 NM_194250.1 1048 cCa/cTa 0 +ZNF804A UCSF GRCh37 2 185802611 185802611 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 88 204 0 ENST00000302277.6:c.2488G>A p.Glu830Lys p.E830K ENST00000302277 NM_194250.1 830 Gaa/Aaa 0 +ZNF808 UCSF GRCh37 19 53057091 53057091 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 158 133 271 0 ENST00000359798.4:c.922C>T p.Leu308Phe p.L308F ENST00000359798 NM_001039886.3 308 Ctt/Ttt 0 +ZNF812 UCSF GRCh37 19 9801409 9801409 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 61 194 0 ENST00000457674.2:c.770C>T p.Ser257Phe p.S257F ENST00000457674 NM_001199814.1 257 tCc/tTc 0 +ZNF814 UCSF GRCh37 19 58384320 58384320 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 125 109 223 0 ENST00000435989.2:c.2438C>T p.Ser813Phe p.S813F ENST00000435989 NM_001144989.1 813 tCc/tTc 0 +ZNF814 UCSF GRCh37 19 58386317 58386317 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 83 254 0 ENST00000435989.2:c.441C>T p.Pro147= p.P147= ENST00000435989 NM_001144989.1 147 ccC/ccT 0 +ZNF828 UCSF GRCh37 13 115090865 115090865 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 144 143 224 0 ENST00000361283.1:c.1548G>A p.Lys516= p.K516= ENST00000361283 NM_032436.2 516 aaG/aaA 0 +ZNF839 UCSF GRCh37 14 102807822 102807822 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 51 135 0 ENST00000558850.1:c.1742C>T p.Ser581Phe p.S581F ENST00000558850 NM_001267827.1 581 tCc/tTc 0 +ZNF878 UCSF GRCh37 19 12155717 12155717 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 154 125 231 0 ENST00000547628.1:c.499G>A p.Ala167Thr p.A167T ENST00000547628 NM_001080404.2 167 Gca/Aca 0 +ZNHIT6 UCSF GRCh37 1 86173894 86173894 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 64 146 0 ENST00000370574.3:c.74G>A p.Ser25Asn p.S25N ENST00000370574 25 aGt/aAt 0 +ZNRF3 UCSF GRCh37 22 29438558 29438558 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 37 68 0 ENST00000544604.2:c.501+1G>A p.X167_splice ENST00000544604 NM_001206998.1 0 +ZNRF3 UCSF GRCh37 22 29445444 29445444 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 47 67 0 ENST00000544604.2:c.1275C>T p.Asp425= p.D425= ENST00000544604 NM_001206998.1 425 gaC/gaT 0 +ZP2 UCSF GRCh37 16 21212793 21212793 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 79 158 0 ENST00000574002.1:c.1591C>T p.Leu531= p.L531= ENST00000574002 531 Cta/Tta 0 +ZP4 UCSF GRCh37 1 238053862 238053862 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 53 119 0 ENST00000366570.4:c.74C>T p.Ala25Val p.A25V ENST00000366570 NM_021186.3 25 gCa/gTa 0 +ZSCAN20 UCSF GRCh37 1 33961067 33961067 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 43 90 0 ENST00000361328.3:c.3123G>A p.Lys1041= p.K1041= ENST00000361328 NM_145238.3 1041 aaG/aaA 0 +ZSCAN29 UCSF GRCh37 15 43654045 43654045 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 76 184 0 ENST00000396976.2:c.1785G>A p.Arg595= p.R595= ENST00000396976 NM_152455.3 595 agG/agA 0 +ZSWIM6 UCSF GRCh37 5 60839601 60839601 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 69 130 0 ENST00000252744.5:c.3105G>A p.Arg1035= p.R1035= ENST00000252744 NM_020928.1 1035 cgG/cgA 0 +ARID2 UCSF GRCh37 12 46242691 46242691 + synonymous_variant Silent SNP G G C NOVEL P11_Pri Untested WXS Illumina HiSeq 90 67 110 0 ENST00000334344.6:c.1653G>C p.Ser551= p.S551= ENST00000334344 NM_152641.2 551 tcG/tcC 0 +ATRX UCSF GRCh37 X 76938945 76938951 + frameshift_variant Frame_Shift_Del DEL TTTAATT TTTAATT - NOVEL P11_Pri Untested WXS Illumina HiSeq 88 0 ENST00000373344.5:c.1797_1803del p.Ile600ValfsTer19 p.I600Vfs*19 ENST00000373344 NM_000489.3 599 ccAATTAAA/cc 0 +CFTR UCSF GRCh37 7 117171029 117171029 + missense_variant Missense_Mutation SNP G G A snp132_rs78655421 P11_Pri Untested WXS Illumina HiSeq 49 39 82 0 ENST00000003084.6:c.350G>A p.Arg117His p.R117H ENST00000003084 NM_000492.3 117 cGc/cAc 0 +DDR1 UCSF GRCh37 6 30865364 30865364 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 33 17 42 0 ENST00000324771.8:c.2206C>T p.Pro736Ser p.P736S ENST00000324771 736 Ccc/Tcc 0 +DUX2 UCSF GRCh37 4 190989798 190989798 + non_coding_transcript_exon_variant RNA SNP G G C NOVEL P11_Pri Untested WXS Illumina HiSeq 14 4 26 1 ENST00000536428.1:n.1003G>C *335* ENST00000536428 0 +FLT4 UCSF GRCh37 5 180038348 180038348 + synonymous_variant Silent SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 55 25 60 0 ENST00000261937.6:c.3669C>T p.Arg1223= p.R1223= ENST00000261937 NM_182925.4 1223 cgC/cgT 0 +GOLGA1 UCSF GRCh37 9 127651492 127651492 + missense_variant Missense_Mutation SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 34 6 44 0 ENST00000373555.4:c.1691C>T p.Ala564Val p.A564V ENST00000373555 NM_002077.3 564 gCg/gTg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 97 70 123 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIAA1958 UCSF GRCh37 9 115336728 115336728 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 81 70 148 0 ENST00000337530.6:c.368C>T p.Ser123Phe p.S123F ENST00000337530 NM_001287038.1 123 tCc/tTc 0 +KIAA2026 UCSF GRCh37 9 5920588 5920588 + missense_variant Missense_Mutation SNP G G T NOVEL P11_Pri Untested WXS Illumina HiSeq 193 40 352 0 ENST00000399933.3:c.5408C>A p.Thr1803Lys p.T1803K ENST00000399933 NM_001017969.2 1803 aCa/aAa 0 +MADCAM1 UCSF GRCh37 19 501701 501701 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.144,1000g2011may_all_0.1863,snp132_rs72970252 P11_Pri Untested WXS Illumina HiSeq 50 7 44 1 ENST00000215637.3:c.700G>A p.Asp234Asn p.D234N ENST00000215637 NM_130760.2 234 Gac/Aac 0 +MKI67 UCSF GRCh37 10 129904284 129904284 + synonymous_variant Silent SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 115 44 236 0 ENST00000368654.3:c.5820G>A p.Arg1940= p.R1940= ENST00000368654 NM_002417.4 1940 cgG/cgA 0 +MYO10 UCSF GRCh37 5 16711041 16711041 + synonymous_variant Silent SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 98 24 118 0 ENST00000513610.1:c.2145C>T p.Ser715= p.S715= ENST00000513610 NM_012334.2 715 agC/agT 0 +NYNRIN UCSF GRCh37 14 24878453 24878453 + missense_variant Missense_Mutation SNP T T C NOVEL P11_Pri Untested WXS Illumina HiSeq 61 27 87 0 ENST00000382554.3:c.1453T>C p.Ser485Pro p.S485P ENST00000382554 NM_025081.2 485 Tct/Cct 0 +PHKA2 UCSF GRCh37 X 18924630 18924630 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 25 26 78 0 ENST00000379942.4:c.2789G>A p.Arg930Gln p.R930Q ENST00000379942 NM_000292.2 930 cGg/cAg 0 +PKD1L1 UCSF GRCh37 7 47913571 47913571 + synonymous_variant Silent SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 31 29 45 0 ENST00000289672.2:c.3822C>T p.Ser1274= p.S1274= ENST00000289672 NM_138295.3 1274 tcC/tcT 0 +PLCH1 UCSF GRCh37 3 155200415 155200415 + missense_variant Missense_Mutation SNP T T C NOVEL P11_Pri Untested WXS Illumina HiSeq 104 15 107 0 ENST00000340059.7:c.3424A>G p.Arg1142Gly p.R1142G ENST00000340059 NM_001130960.1 1142 Agg/Ggg 0 +PTCRA UCSF GRCh37 6 42893351 42893351 + synonymous_variant Silent SNP T T G NOVEL P11_Pri Untested WXS Illumina HiSeq 12 15 27 0 ENST00000304672.1:c.777T>G p.Ala259= p.A259= ENST00000304672 NM_001243168.1 259 gcT/gcG 0 +RGS5 UCSF GRCh37 1 163138051 163138051 + missense_variant Missense_Mutation SNP T T A NOVEL P11_Pri Untested WXS Illumina HiSeq 105 34 171 0 ENST00000313961.5:c.152A>T p.Gln51Leu p.Q51L ENST00000313961 NM_003617.3 51 cAg/cTg 0 +SIDT2 UCSF GRCh37 11 117060735 117060735 + missense_variant Missense_Mutation SNP A A G NOVEL P11_Pri Untested WXS Illumina HiSeq 54 35 122 0 ENST00000324225.4:c.1487A>G p.Asn496Ser p.N496S ENST00000324225 NM_001040455.1 496 aAt/aGt 0 +SLAMF1 UCSF GRCh37 1 160589601 160589601 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P11_Pri Untested WXS Illumina HiSeq 6 0 ENST00000302035.6:c.829delA p.Ser277AlafsTer54 p.S277Afs*54 ENST00000302035 NM_003037.2 277 Agc/gc 0 +SLX4 UCSF GRCh37 16 3633500 3633500 + missense_variant Missense_Mutation SNP C C A NOVEL P11_Pri Untested WXS Illumina HiSeq 77 10 85 0 ENST00000294008.3:c.4751G>T p.Arg1584Leu p.R1584L ENST00000294008 NM_032444.2 1584 cGc/cTc 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 11 71 50 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TXNDC3 UCSF GRCh37 7 37936603 37936603 + missense_variant Missense_Mutation SNP G G T NOVEL P11_Pri Untested WXS Illumina HiSeq 88 23 143 0 ENST00000199447.4:c.1676G>T p.Ser559Ile p.S559I ENST00000199447 NM_016616.4 559 aGt/aTt 0 +UNC5C UCSF GRCh37 4 96104084 96104084 + synonymous_variant Silent SNP T T C NOVEL P11_Pri Untested WXS Illumina HiSeq 91 62 153 0 ENST00000453304.1:c.2415A>G p.Glu805= p.E805= ENST00000453304 NM_003728.3 805 gaA/gaG 0 +WASH1 UCSF GRCh37 9 16967 16967 + splice_region_variant,non_coding_transcript_exon_variant Splice_Region SNP A A G 1000g2011may_all_0.2384,snp132_rs17857353 P11_Pri Untested WXS Illumina HiSeq 42 7 40 0 ENST00000442898.2:n.1024T>C p.X342_splice ENST00000442898 0 +ZNF483 UCSF GRCh37 9 114304413 114304413 + missense_variant Missense_Mutation SNP A A C NOVEL P11_Pri Untested WXS Illumina HiSeq 120 102 195 0 ENST00000309235.5:c.1198A>C p.Ile400Leu p.I400L ENST00000309235 NM_133464.2 400 Att/Ctt 0 +ALDH3B1 UCSF GRCh37 11 67795299 67795299 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.237,1000g2011may_all_0.3285,snp132_rs308341 P11_Rec Untested WXS Illumina HiSeq 5 11 8 0 ENST00000342456.6:c.1185G>A p.Pro395= p.P395= ENST00000342456 NM_001030010.1 395 ccG/ccA 0 +APOF UCSF GRCh37 12 56755364 56755364 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P11_Rec Untested WXS Illumina HiSeq 10 0 ENST00000398189.3:c.626del p.Lys209ArgfsTer11 p.K209Rfs*11 ENST00000398189 NM_001638.2 209 aAg/ag 0 +ARID2 UCSF GRCh37 12 46242691 46242691 + synonymous_variant Silent SNP G G C NOVEL P11_Rec Untested WXS Illumina HiSeq 75 42 110 0 ENST00000334344.6:c.1653G>C p.Ser551= p.S551= ENST00000334344 NM_152641.2 551 tcG/tcC 0 +ATRX UCSF GRCh37 X 76938945 76938951 + frameshift_variant Frame_Shift_Del DEL TTTAATT TTTAATT - NOVEL P11_Rec Untested WXS Illumina HiSeq 65 0 ENST00000373344.5:c.1797_1803del p.Ile600ValfsTer19 p.I600Vfs*19 ENST00000373344 NM_000489.3 599 ccAATTAAA/cc 0 +C7orf57 UCSF GRCh37 7 48080945 48080945 + missense_variant Missense_Mutation SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 102 15 115 1 ENST00000348904.3:c.70G>A p.Val24Ile p.V24I ENST00000348904 NM_001100159.2 24 Gtc/Atc 0 +CFTR UCSF GRCh37 7 117171029 117171029 + missense_variant Missense_Mutation SNP G G A snp132_rs78655421 P11_Rec Untested WXS Illumina HiSeq 62 26 82 0 ENST00000003084.6:c.350G>A p.Arg117His p.R117H ENST00000003084 NM_000492.3 117 cGc/cAc 0 +CLIP1 UCSF GRCh37 12 122758571 122758599 + splice_donor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TTCATATGAAATACCTGTCATAATTGTTT TTCATATGAAATACCTGTCATAATTGTTT - NOVEL P11_Rec Untested WXS Illumina HiSeq 6 0 ENST00000540338.1:c.4077_4091+14del p.X1359_splice ENST00000540338 1359 0 +CREG2 UCSF GRCh37 2 101971731 101971731 + missense_variant Missense_Mutation SNP G G T NOVEL P11_Rec Untested WXS Illumina HiSeq 72 12 52 1 ENST00000324768.5:c.709C>A p.Gln237Lys p.Q237K ENST00000324768 NM_153836.3 237 Caa/Aaa 0 +CROCC UCSF GRCh37 1 17272075 17272075 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.064,1000g2011may_all_0.0426,snp132_rs2781608 P11_Rec Untested WXS Illumina HiSeq 15 4 26 1 ENST00000375541.5:c.2110G>A p.Ala704Thr p.A704T ENST00000375541 NM_014675.3 704 Gcc/Acc 0 +CYP21A2 UCSF GRCh37 6 31975463 31975463 + non_coding_transcript_exon_variant RNA SNP T T C 1000g2011may_all_0.0497,snp132_rs7755898 P11_Rec Untested WXS Illumina HiSeq 18 4 12 0 ENST00000342991.6:n.1386T>C *462* ENST00000342991 0 +DDR1 UCSF GRCh37 6 30865364 30865364 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 39 28 42 0 ENST00000324771.8:c.2206C>T p.Pro736Ser p.P736S ENST00000324771 736 Ccc/Tcc 0 +DEFB126 UCSF GRCh37 20 126310 126311 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P11_Rec Untested WXS Illumina HiSeq 6 0 ENST00000382398.3:c.313_314del p.Thr105ProfsTer? p.T105Pfs*? ENST00000382398 NM_030931.3 105 ACc/c 0 +FLT4 UCSF GRCh37 5 180038348 180038348 + synonymous_variant Silent SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 51 22 60 0 ENST00000261937.6:c.3669C>T p.Arg1223= p.R1223= ENST00000261937 NM_182925.4 1223 cgC/cgT 0 +GGTLC1 UCSF GRCh37 20 23967157 23967157 + missense_variant Missense_Mutation SNP A A G NOVEL P11_Rec Untested WXS Illumina HiSeq 37 12 53 0 ENST00000278765.4:c.92T>C p.Met31Thr p.M31T ENST00000278765 NM_178312.2 31 aTg/aCg 0 +GNRH2 UCSF GRCh37 20 3026346 3026347 + frameshift_variant Frame_Shift_Ins INS - - GCCCC NOVEL P11_Rec Untested WXS Illumina HiSeq 6 0 ENST00000245983.2:c.327_328insGCCCC p.Pro110AlafsTer? p.P110Afs*? ENST00000245983 NM_001501.1 109 -/GCCCC 0 +GPRC5B UCSF GRCh37 16 19883854 19883854 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 50 8 46 0 ENST00000300571.2:c.314G>A p.Gly105Asp p.G105D ENST00000300571 NM_016235.1 105 gGc/gAc 0 +HLA-A UCSF GRCh37 6 29910572 29910572 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.067,1000g2011may_all_0.0966,snp132_rs114101108 P11_Rec Untested WXS Illumina HiSeq 26 5 38 0 ENST00000396634.1:c.112C>T p.Arg38Trp p.R38W ENST00000396634 38 Cgg/Tgg 0 +HLA-A UCSF GRCh37 6 29910558 29910558 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.473,1000g2011may_all_0.5687,snp132_rs112039894 P11_Rec Untested WXS Illumina HiSeq 19 4 37 1 ENST00000396634.1:c.98T>C p.Phe33Ser p.F33S ENST00000396634 33 tTc/tCc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 100 60 123 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KBTBD6 UCSF GRCh37 13 41704817 41704820 + frameshift_variant Frame_Shift_Del DEL AGTT AGTT - NOVEL P11_Rec Untested WXS Illumina HiSeq 7 0 ENST00000379485.1:c.1828_1831del p.Asn610PhefsTer36 p.N610Ffs*36 ENST00000379485 NM_152903.4 610 AACTtt/tt 0 +KIAA1958 UCSF GRCh37 9 115336728 115336728 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 92 60 148 0 ENST00000337530.6:c.368C>T p.Ser123Phe p.S123F ENST00000337530 NM_001287038.1 123 tCc/tTc 0 +KIAA2026 UCSF GRCh37 9 5920588 5920588 + missense_variant Missense_Mutation SNP G G T NOVEL P11_Rec Untested WXS Illumina HiSeq 231 37 352 0 ENST00000399933.3:c.5408C>A p.Thr1803Lys p.T1803K ENST00000399933 NM_001017969.2 1803 aCa/aAa 0 +MIS18BP1 UCSF GRCh37 14 45716019 45716020 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P11_Rec Untested WXS Illumina HiSeq 6 0 ENST00000310806.4:c.471dup p.Leu158IlefsTer8 p.L158Ifs*8 ENST00000310806 NM_018353.4 157 aaa/aaAa 0 +MKI67 UCSF GRCh37 10 129904284 129904284 + synonymous_variant Silent SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 157 34 236 0 ENST00000368654.3:c.5820G>A p.Arg1940= p.R1940= ENST00000368654 NM_002417.4 1940 cgG/cgA 0 +MST1 UCSF GRCh37 3 49723545 49723545 + 3_prime_UTR_variant 3'UTR SNP G G A snp132_rs4052562 P11_Rec Untested WXS Illumina HiSeq 32 6 25 1 ENST00000383728.3:c.*197C>T *66* ENST00000383728 0 +MST1 UCSF GRCh37 3 49723542 49723542 + 3_prime_UTR_variant 3'UTR SNP G G C snp132_rs2087732 P11_Rec Untested WXS Illumina HiSeq 33 6 25 1 ENST00000383728.3:c.*200C>G *67* ENST00000383728 0 +MYO10 UCSF GRCh37 5 16711041 16711041 + synonymous_variant Silent SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 125 24 118 0 ENST00000513610.1:c.2145C>T p.Ser715= p.S715= ENST00000513610 NM_012334.2 715 agC/agT 0 +NBPF4 UCSF GRCh37 1 108769307 108769307 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.062,1000g2011may_all_0.2082,snp132_rs2582071 P11_Rec Untested WXS Illumina HiSeq 72 10 79 1 ENST00000415641.3:c.1869C>T p.Ser623= p.S623= ENST00000415641 NM_001143989.2 623 agC/agT 0 +NYNRIN UCSF GRCh37 14 24878453 24878453 + missense_variant Missense_Mutation SNP T T C NOVEL P11_Rec Untested WXS Illumina HiSeq 86 37 87 0 ENST00000382554.3:c.1453T>C p.Ser485Pro p.S485P ENST00000382554 NM_025081.2 485 Tct/Cct 0 +PEAK1 UCSF GRCh37 15 77473938 77473939 + frameshift_variant Frame_Shift_Del DEL AG AG - NOVEL P11_Rec Untested WXS Illumina HiSeq 7 0 ENST00000312493.4:c.330_331del p.Leu111GlufsTer6 p.L111Efs*6 ENST00000312493 NM_024776.3 110 gcCTtg/gctg 0 +PHKA2 UCSF GRCh37 X 18924630 18924630 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 56 37 78 0 ENST00000379942.4:c.2789G>A p.Arg930Gln p.R930Q ENST00000379942 NM_000292.2 930 cGg/cAg 0 +PKD1L1 UCSF GRCh37 7 47913571 47913571 + synonymous_variant Silent SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 32 25 45 0 ENST00000289672.2:c.3822C>T p.Ser1274= p.S1274= ENST00000289672 NM_138295.3 1274 tcC/tcT 0 +PTCRA UCSF GRCh37 6 42893351 42893351 + synonymous_variant Silent SNP T T G NOVEL P11_Rec Untested WXS Illumina HiSeq 17 9 27 0 ENST00000304672.1:c.777T>G p.Ala259= p.A259= ENST00000304672 NM_001243168.1 259 gcT/gcG 0 +RGS5 UCSF GRCh37 1 163138051 163138051 + missense_variant Missense_Mutation SNP T T A NOVEL P11_Rec Untested WXS Illumina HiSeq 129 29 171 0 ENST00000313961.5:c.152A>T p.Gln51Leu p.Q51L ENST00000313961 NM_003617.3 51 cAg/cTg 0 +SIDT2 UCSF GRCh37 11 117060735 117060735 + missense_variant Missense_Mutation SNP A A G NOVEL P11_Rec Untested WXS Illumina HiSeq 84 48 122 0 ENST00000324225.4:c.1487A>G p.Asn496Ser p.N496S ENST00000324225 NM_001040455.1 496 aAt/aGt 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 26 58 50 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TPSAB1 UCSF GRCh37 16 1291639 1291639 + synonymous_variant Silent SNP A A G snp132_rs1064783 P11_Rec Untested WXS Illumina HiSeq 75 9 60 1 ENST00000338844.3:c.438A>G p.Ser146= p.S146= ENST00000338844 NM_003294.3 146 tcA/tcG 0 +UNC5C UCSF GRCh37 4 96104084 96104084 + synonymous_variant Silent SNP T T C NOVEL P11_Rec Untested WXS Illumina HiSeq 107 35 153 0 ENST00000453304.1:c.2415A>G p.Glu805= p.E805= ENST00000453304 NM_003728.3 805 gaA/gaG 0 +WDR81 UCSF GRCh37 17 1637482 1637482 + synonymous_variant Silent SNP G G T NOVEL P11_Rec Untested WXS Illumina HiSeq 29 4 27 0 ENST00000409644.1:c.5151G>T p.Gly1717= p.G1717= ENST00000409644 NM_001163809.1 1717 ggG/ggT 0 +ZNF483 UCSF GRCh37 9 114304413 114304413 + missense_variant Missense_Mutation SNP A A C NOVEL P11_Rec Untested WXS Illumina HiSeq 180 95 195 0 ENST00000309235.5:c.1198A>C p.Ile400Leu p.I400L ENST00000309235 NM_133464.2 400 Att/Ctt 0 +ASB5 UCSF GRCh37 4 177142715 177142715 + missense_variant Missense_Mutation SNP A A G NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 97 86 133 0 ENST00000296525.3:c.421T>C p.Phe141Leu p.F141L ENST00000296525 NM_080874.3 141 Ttc/Ctc 0 +ATRX UCSF GRCh37 X 76939908 76939920 + frameshift_variant Frame_Shift_Del DEL ACATGCAGTGACC ACATGCAGTGACC - NOVEL P12_Pri Untested WXS Illumina HiSeq 116 0 ENST00000373344.5:c.828_840del p.Val277ThrfsTer7 p.V277Tfs*7 ENST00000373344 NM_000489.3 276 ttGGTCACTGCATGT/tt 0 +C7orf57 UCSF GRCh37 7 48086205 48086205 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P12_Pri Untested WXS Illumina HiSeq 6 0 ENST00000348904.3:c.506del p.Lys169SerfsTer2 p.K169Sfs*2 ENST00000348904 NM_001100159.2 167 Aaa/aa 0 +CAND1 UCSF GRCh37 12 67686492 67686492 + synonymous_variant Silent SNP A A G NOVEL P12_Pri Untested WXS Illumina HiSeq 129 94 156 0 ENST00000545606.1:c.303A>G p.Gln101= p.Q101= ENST00000545606 NM_018448.3 101 caA/caG 0 +CHST8 UCSF GRCh37 19 34263267 34263267 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 8 9 63 0 ENST00000262622.4:c.574G>A p.Val192Met p.V192M ENST00000262622 NM_022467.3 192 Gtg/Atg 0 +COL6A3 UCSF GRCh37 2 238253159 238253159 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Pri Untested WXS Illumina HiSeq 123 98 164 0 ENST00000295550.4:c.7502G>A p.Arg2501His p.R2501H ENST00000295550 NM_004369.3 2501 cGt/cAt 0 +DGAT2L6 UCSF GRCh37 X 69424267 69424268 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P12_Pri Untested WXS Illumina HiSeq 39 0 ENST00000333026.3:c.766dup p.Ile256AsnfsTer42 p.I256Nfs*42 ENST00000333026 NM_198512.1 254 aaa/aAaa 0 +DNMT1 UCSF GRCh37 19 10270707 10270742 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACTGTTTTGGCGCGAGCCATTTTTTTCTCCGTTCTG ACTGTTTTGGCGCGAGCCATTTTTTTCTCCGTTCTG TTTGTTTGGGCGGGAGCCATTTTTTTCTCCGTTCT NOVEL P12_Pri Untested WXS Illumina HiSeq 6 0 ENST00000340748.4:c.996-3_1028delinsAGAACGGAGAAAAAAATGGCTCCCGCCCAAACAAA p.X332_splice ENST00000340748 0 +FAF2 UCSF GRCh37 5 175927025 175927025 + missense_variant Missense_Mutation SNP A A G NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 102 67 142 0 ENST00000261942.6:c.1033A>G p.Arg345Gly p.R345G ENST00000261942 NM_014613.2 345 Agg/Ggg 0 +GPC2 UCSF GRCh37 7 99773267 99773267 + synonymous_variant Silent SNP G G C NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 41 33 71 0 ENST00000292377.2:c.576C>G p.Leu192= p.L192= ENST00000292377 NM_152742.1 192 ctC/ctG 0 +IARS UCSF GRCh37 9 95040528 95040528 + synonymous_variant Silent SNP T T C NOVEL P12_Pri Untested WXS Illumina HiSeq 143 113 180 0 ENST00000375643.3:c.786A>G p.Arg262= p.R262= ENST00000375643 NM_013417.3 262 agA/agG 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 91 85 125 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIF25 UCSF GRCh37 6 168430348 168430348 + missense_variant Missense_Mutation SNP A A T 1000g2010nov_all_0.200,1000g2011may_all_0.2270,snp132_rs4708626 P12_Pri Untested WXS Illumina HiSeq 87 10 75 1 ENST00000354419.2:c.83A>T p.Lys28Met p.K28M ENST00000354419 NM_030615.2 28 aAg/aTg 0 +ODZ4 UCSF GRCh37 11 78437125 78437125 + splice_region_variant,synonymous_variant Splice_Region SNP A A G NOVEL P12_Pri Untested WXS Illumina HiSeq 208 105 203 0 ENST00000278550.7:c.3549T>C p.Ser1183= p.S1183= ENST00000278550 NM_001098816.2 1183 agT/agC 0 +PI4KA UCSF GRCh37 22 21065645 21065645 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.330,1000g2011may_all_0.3814,snp132_rs1135934 P12_Pri Untested WXS Illumina HiSeq 33 4 34 1 ENST00000255882.6:c.5907T>C p.Gly1969= p.G1969= ENST00000255882 NM_058004.3 1969 ggT/ggC 0 +PIEZO2 UCSF GRCh37 18 10758061 10758061 + stop_gained Nonsense_Mutation SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 136 101 193 0 ENST00000503781.3:c.3754C>T p.Arg1252Ter p.R1252* ENST00000503781 NM_022068.2 1252 Cga/Tga 0 +PMEL UCSF GRCh37 12 56351767 56351767 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 91 63 132 0 ENST00000548493.1:c.571C>T p.Arg191Cys p.R191C ENST00000548493 191 Cgc/Tgc 0 +SAG UCSF GRCh37 2 234224735 234224735 + synonymous_variant Silent SNP G G C NOVEL P12_Pri Untested WXS Illumina HiSeq 91 50 147 0 ENST00000409110.1:c.90G>C p.Leu30= p.L30= ENST00000409110 NM_000541.4 30 ctG/ctC 0 +SEZ6L2 UCSF GRCh37 16 29900024 29900024 + synonymous_variant Silent SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 48 10 41 1 ENST00000308713.5:c.876C>T p.Phe292= p.F292= ENST00000308713 NM_001114099.2 292 ttC/ttT 0 +SLC38A4 UCSF GRCh37 12 47186817 47186817 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 135 78 178 0 ENST00000266579.4:c.38C>T p.Pro13Leu p.P13L ENST00000266579 NM_018018.4 13 cCa/cTa 0 +SLC7A2 UCSF GRCh37 8 17401018 17401018 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 82 70 103 0 ENST00000494857.1:c.170G>A p.Gly57Glu p.G57E ENST00000494857 NM_001008539.3 57 gGg/gAg 0 +TP53 UCSF GRCh37 17 7578406 7578406 + missense_variant Missense_Mutation SNP C C T snp132_rs28934578 P12_Pri somatic WXS Sanger Illumina HiSeq 10 100 87 0 ENST00000269305.4:c.524G>A p.Arg175His p.R175H ENST00000269305 NM_001126112.2 175 cGc/cAc 0 +ADAM20 UCSF GRCh37 14 70990780 70990780 + missense_variant Missense_Mutation SNP T T C NOVEL P12_Rec Untested WXS Illumina HiSeq 61 92 164 0 ENST00000256389.3:c.845A>G p.His282Arg p.H282R ENST00000256389 NM_003814.4 282 cAt/cGt 0 +ASB5 UCSF GRCh37 4 177142715 177142715 + missense_variant Missense_Mutation SNP A A G NOVEL P12_Rec somatic WXS Sanger Illumina HiSeq 101 70 133 0 ENST00000296525.3:c.421T>C p.Phe141Leu p.F141L ENST00000296525 NM_080874.3 141 Ttc/Ctc 0 +ATP8B1 UCSF GRCh37 18 55315829 55315829 + missense_variant Missense_Mutation SNP C C G NOVEL P12_Rec Untested WXS Illumina HiSeq 28 6 35 0 ENST00000283684.4:c.3647G>C p.Gly1216Ala p.G1216A ENST00000283684 1216 gGc/gCc 0 +ATP8B1 UCSF GRCh37 18 55315832 55315832 + missense_variant Missense_Mutation SNP C C A NOVEL P12_Rec Untested WXS Illumina HiSeq 25 7 34 0 ENST00000283684.4:c.3644G>T p.Arg1215Leu p.R1215L ENST00000283684 1215 cGg/cTg 0 +ATRX UCSF GRCh37 X 76939908 76939920 + frameshift_variant Frame_Shift_Del DEL ACATGCAGTGACC ACATGCAGTGACC - NOVEL P12_Rec Untested WXS Illumina HiSeq 86 0 ENST00000373344.5:c.828_840del p.Val277ThrfsTer7 p.V277Tfs*7 ENST00000373344 NM_000489.3 276 ttGGTCACTGCATGT/tt 0 +B3GNT3 UCSF GRCh37 19 17922618 17922618 + missense_variant Missense_Mutation SNP G G C NOVEL P12_Rec Untested WXS Illumina HiSeq 79 141 113 0 ENST00000318683.6:c.806G>C p.Gly269Ala p.G269A ENST00000318683 NM_014256.3 269 gGg/gCg 0 +CACNA1E UCSF GRCh37 1 181686272 181686272 + synonymous_variant Silent SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 137 124 155 0 ENST00000367573.2:c.1359C>T p.Asp453= p.D453= ENST00000367573 NM_001205293.1 453 gaC/gaT 0 +COL6A3 UCSF GRCh37 2 238253159 238253159 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 124 86 164 0 ENST00000295550.4:c.7502G>A p.Arg2501His p.R2501H ENST00000295550 NM_004369.3 2501 cGt/cAt 0 +DGAT2L6 UCSF GRCh37 X 69424267 69424268 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P12_Rec Untested WXS Illumina HiSeq 30 0 ENST00000333026.3:c.766dup p.Ile256AsnfsTer42 p.I256Nfs*42 ENST00000333026 NM_198512.1 254 aaa/aAaa 0 +EVX2 UCSF GRCh37 2 176945393 176945393 + synonymous_variant Silent SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 7 10 14 0 ENST00000308618.4:c.873C>T p.Gly291= p.G291= ENST00000308618 NM_001080458.1 291 ggC/ggT 0 +GFPT2 UCSF GRCh37 5 179755331 179755331 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 119 20 56 0 ENST00000253778.8:c.542C>T p.Ala181Val p.A181V ENST00000253778 NM_005110.2 181 gCa/gTa 0 +GIPC2 UCSF GRCh37 1 78560731 78560731 + synonymous_variant Silent SNP T T C NOVEL P12_Rec Untested WXS Illumina HiSeq 158 87 172 0 ENST00000370759.3:c.522T>C p.Arg174= p.R174= ENST00000370759 NM_017655.4 174 cgT/cgC 0 +IARS UCSF GRCh37 9 95040528 95040528 + synonymous_variant Silent SNP T T C NOVEL P12_Rec Untested WXS Illumina HiSeq 126 104 180 0 ENST00000375643.3:c.786A>G p.Arg262= p.R262= ENST00000375643 NM_013417.3 262 agA/agG 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Rec somatic WXS Sanger Illumina HiSeq 75 63 125 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KBTBD5 UCSF GRCh37 3 42728091 42728091 + synonymous_variant Silent SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 123 24 108 0 ENST00000287777.4:c.981C>T p.Gly327= p.G327= ENST00000287777 NM_152393.3 327 ggC/ggT 0 +KIAA0430 UCSF GRCh37 16 15727556 15727556 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 115 101 173 0 ENST00000396368.3:c.1151G>A p.Gly384Asp p.G384D ENST00000396368 NM_001184998.1 384 gGc/gAc 0 +MRC2 UCSF GRCh37 17 60744152 60744152 + synonymous_variant Silent SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 15 15 29 0 ENST00000303375.5:c.894C>T p.Ile298= p.I298= ENST00000303375 NM_006039.4 298 atC/atT 0 +PIEZO2 UCSF GRCh37 18 10758061 10758061 + stop_gained Nonsense_Mutation SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 153 99 193 0 ENST00000503781.3:c.3754C>T p.Arg1252Ter p.R1252* ENST00000503781 NM_022068.2 1252 Cga/Tga 0 +PITX2 UCSF GRCh37 4 111553569 111553569 + synonymous_variant Silent SNP C C G NOVEL P12_Rec Untested WXS Illumina HiSeq 94 19 85 0 ENST00000354925.2:c.114G>C p.Thr38= p.T38= ENST00000354925 NM_001204397.1 38 acG/acC 0 +PMEL UCSF GRCh37 12 56351767 56351767 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 82 73 132 0 ENST00000548493.1:c.571C>T p.Arg191Cys p.R191C ENST00000548493 191 Cgc/Tgc 0 +SLC7A2 UCSF GRCh37 8 17401018 17401018 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 61 64 103 0 ENST00000494857.1:c.170G>A p.Gly57Glu p.G57E ENST00000494857 NM_001008539.3 57 gGg/gAg 0 +SMARCA4 UCSF GRCh37 19 11132549 11132549 + missense_variant Missense_Mutation SNP G G C NOVEL P12_Rec somatic WXS Sanger Illumina HiSeq 46 86 75 0 ENST00000344626.4:c.2765G>C p.Trp922Ser p.W922S ENST00000344626 NM_003072.3 922 tGg/tCg 0 +SSPO UCSF GRCh37 7 149490407 149490407 + non_coding_transcript_exon_variant RNA SNP G G A 1000g2011may_all_0.0039 P12_Rec Untested WXS Illumina HiSeq 15 7 23 0 ENST00000378016.2:n.5883G>A *1961* ENST00000378016 0 +TCHP UCSF GRCh37 12 110346455 110346455 + missense_variant Missense_Mutation SNP A A G snp132_rs78378786 P12_Rec Untested WXS Illumina HiSeq 18 4 28 1 ENST00000312777.5:c.764A>G p.Glu255Gly p.E255G ENST00000312777 NM_032300.4 255 gAg/gGg 0 +TMTC1 UCSF GRCh37 12 29920865 29920865 + missense_variant Missense_Mutation SNP A A C NOVEL P12_Rec Untested WXS Illumina HiSeq 121 15 130 0 ENST00000539277.1:c.446T>G p.Leu149Trp p.L149W ENST00000539277 NM_001193451.1 149 tTg/tGg 0 +TP53 UCSF GRCh37 17 7578406 7578406 + missense_variant Missense_Mutation SNP C C T snp132_rs28934578 P12_Rec somatic WXS Sanger Illumina HiSeq 9 99 87 0 ENST00000269305.4:c.524G>A p.Arg175His p.R175H ENST00000269305 NM_001126112.2 175 cGc/cAc 0 +WDFY3 UCSF GRCh37 4 85605229 85605229 + missense_variant Missense_Mutation SNP T T C NOVEL P12_Rec Untested WXS Illumina HiSeq 90 77 121 0 ENST00000295888.4:c.9593A>G p.Asn3198Ser p.N3198S ENST00000295888 NM_014991.4 3198 aAt/aGt 0 +ZBTB45 UCSF GRCh37 19 59028912 59028912 + synonymous_variant Silent SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 58 51 74 0 ENST00000354590.3:c.129G>A p.Ser43= p.S43= ENST00000354590 NM_032792.2 43 tcG/tcA 0 +AIM2 UCSF GRCh37 1 159032487 159032488 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000368130.4:c.1027dup p.Thr343AsnfsTer5 p.T343Nfs*5 ENST00000368130 NM_004833.1 342 -/A 0 +ASH1L UCSF GRCh37 1 155308000 155308000 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P13_Pri Untested WXS Illumina HiSeq 8 0 ENST00000368346.3:c.8698delA p.Thr2900GlnfsTer44 p.T2900Qfs*44 ENST00000368346 2900 Aca/ca 0 +ATRX UCSF GRCh37 X 76918952 76918955 + frameshift_variant Frame_Shift_Del DEL CAGT CAGT - NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 33 0 ENST00000373344.5:c.4036_4039del p.Thr1346Ter p.T1346* ENST00000373344 NM_000489.3 1346 ACTGtg/tg 0 +CDC7 UCSF GRCh37 1 91967357 91967357 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000234626.6:c.92delA p.Asn31ThrfsTer51 p.N31Tfs*51 ENST00000234626 NM_001134419.1 28 ttA/tt 0 +CNOT1 UCSF GRCh37 16 58580377 58580377 + missense_variant Missense_Mutation SNP A A C NOVEL P13_Pri Untested WXS Illumina HiSeq 110 21 126 1 ENST00000317147.5:c.3854T>G p.Val1285Gly p.V1285G ENST00000317147 NM_016284.4 1285 gTt/gGt 0 +CNOT1 UCSF GRCh37 16 58612662 58612662 + missense_variant Missense_Mutation SNP T T C snp132_rs112226008 P13_Pri Untested WXS Illumina HiSeq 115 58 147 0 ENST00000317147.5:c.1525A>G p.Ile509Val p.I509V ENST00000317147 NM_016284.4 509 Att/Gtt 0 +COL12A1 UCSF GRCh37 6 75890724 75890724 + missense_variant Missense_Mutation SNP C C A NOVEL P13_Pri Untested WXS Illumina HiSeq 99 38 171 0 ENST00000322507.8:c.2095G>T p.Val699Phe p.V699F ENST00000322507 NM_004370.5 699 Gtc/Ttc 0 +CR2 UCSF GRCh37 1 207643301 207643301 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 108 40 154 0 ENST00000367058.3:c.1079G>A p.Arg360Gln p.R360Q ENST00000367058 NM_001877.4 360 cGa/cAa 0 +DYNC1I2 UCSF GRCh37 2 172549339 172549339 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P13_Pri Untested WXS Illumina HiSeq 7 0 ENST00000397119.3:c.169delA p.Arg57GlyfsTer13 p.R57Gfs*13 ENST00000397119 NM_001378.2 54 gAa/ga 0 +ELL2 UCSF GRCh37 5 95231362 95231362 + missense_variant Missense_Mutation SNP G G C NOVEL P13_Pri Untested WXS Illumina HiSeq 65 24 72 0 ENST00000237853.4:c.1559C>G p.Pro520Arg p.P520R ENST00000237853 NM_012081.5 520 cCt/cGt 0 +FAR2 UCSF GRCh37 12 29450110 29450110 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000182377.4:c.529delA p.Ile177SerfsTer8 p.I177Sfs*8 ENST00000182377 NM_018099.4 174 ccA/cc 0 +FGF12 UCSF GRCh37 3 191888444 191888444 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P13_Pri Untested WXS Illumina HiSeq 132 52 164 0 ENST00000454309.2:c.416A>G p.Asp139Gly p.D139G ENST00000454309 NM_021032.4 139 gAt/gGt 0 +FMN2 UCSF GRCh37 1 240371223 240371223 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.149 P13_Pri Untested WXS Illumina HiSeq 12 4 18 0 ENST00000319653.9:c.3111C>T p.Pro1037= p.P1037= ENST00000319653 NM_020066.4 1037 ccC/ccT 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G C NOVEL P13_Pri Untested WXS Illumina HiSeq 86 33 136 0 ENST00000345146.2:c.394C>G p.Arg132Gly p.R132G ENST00000345146 NM_005896.2 132 Cgt/Ggt 0 +INTU UCSF GRCh37 4 128564702 128564702 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 174 37 199 0 ENST00000335251.6:c.173G>A p.Ser58Asn p.S58N ENST00000335251 NM_015693.3 58 aGt/aAt 0 +KLF17 UCSF GRCh37 1 44595246 44595246 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P13_Pri Untested WXS Illumina HiSeq 7 0 ENST00000372299.3:c.307del p.Gln103LysfsTer9 p.Q103Kfs*9 ENST00000372299 NM_173484.3 101 tgC/tg 0 +MUC5B UCSF GRCh37 11 1253980 1253980 + missense_variant Missense_Mutation SNP A A G 1000g2010nov_all_0.103,snp132_rs115853043 P13_Pri Untested WXS Illumina HiSeq 11 5 19 1 ENST00000529681.1:c.2045A>G p.Asp682Gly p.D682G ENST00000529681 NM_002458.2 682 gAc/gGc 0 +PCLO UCSF GRCh37 7 82581498 82581499 + inframe_insertion In_Frame_Ins INS - - TCT NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000333891.9:c.8770_8771insAGA p.Ile2923_Ile2924insLys p.I2923_I2924insK ENST00000333891 NM_033026.5 2924 ata/aAGAta 0 +PRDM9 UCSF GRCh37 5 23510029 23510029 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 77 20 101 0 ENST00000296682.3:c.194G>A p.Gly65Asp p.G65D ENST00000296682 NM_020227.2 65 gGt/gAt 0 +PZP UCSF GRCh37 12 9349246 9349246 + synonymous_variant Silent SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 235 35 221 0 ENST00000261336.2:c.903C>T p.His301= p.H301= ENST00000261336 NM_002864.2 301 caC/caT 0 +SEMA4B UCSF GRCh37 15 90771680 90771680 + synonymous_variant Silent SNP C C T NOVEL P13_Pri Untested WXS Illumina HiSeq 55 24 94 0 ENST00000411539.2:c.2319C>T p.Asn773= p.N773= ENST00000411539 NM_198925.2 773 aaC/aaT 0 +SHROOM3 UCSF GRCh37 4 77675759 77675759 + stop_gained Nonsense_Mutation SNP C C T NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 45 22 101 0 ENST00000296043.6:c.4123C>T p.Arg1375Ter p.R1375* ENST00000296043 NM_020859.3 1375 Cga/Tga 0 +SLFN13 UCSF GRCh37 17 33771784 33771784 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.015,1000g2011may_all_0.0426,snp132_rs78359177 P13_Pri Untested WXS Illumina HiSeq 146 67 188 0 ENST00000285013.6:c.916G>C p.Glu306Gln p.E306Q ENST00000285013 NM_144682.5 306 Gag/Cag 0 +TKTL2 UCSF GRCh37 4 164394416 164394416 + synonymous_variant Silent SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 110 18 145 0 ENST00000280605.3:c.471C>T p.Gly157= p.G157= ENST00000280605 NM_032136.4 157 ggC/ggT 0 +TP53 UCSF GRCh37 17 7579370 7579370 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 41 0 ENST00000269305.4:c.317del p.Ser106ThrfsTer17 p.S106Tfs*17 ENST00000269305 NM_001126112.2 106 aGc/ac 0 +TP53 UCSF GRCh37 17 7577515 7577516 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 11 0 ENST00000269305.4:c.766dup p.Thr256AsnfsTer8 p.T256Nfs*8 ENST00000269305 NM_001126112.2 255 -/A 0 +TRIO UCSF GRCh37 5 14389501 14389503 + inframe_deletion In_Frame_Del DEL ATA ATA - NOVEL P13_Pri Untested WXS Illumina HiSeq 8 0 ENST00000344204.4:c.4056_4058del p.Asn1353del p.N1353del ENST00000344204 NM_007118.2 1351 cATAat/cat 0 +TTC28 UCSF GRCh37 22 28501647 28501647 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 103 65 194 0 ENST00000397906.2:c.2927C>T p.Ala976Val p.A976V ENST00000397906 NM_001145418.1 976 gCc/gTc 0 +UBE2J2 UCSF GRCh37 1 1191458 1191459 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P13_Pri Untested WXS Illumina HiSeq 16 0 ENST00000349431.6:c.461_462del p.Lys154SerfsTer4 p.K154Sfs*4 ENST00000349431 NM_058167.2 154 aAA/a 0 +ZRANB3 UCSF GRCh37 2 136148382 136148396 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACCATACACCTGGAA ACCATACACCTGGAA CCCAAACCCCTGG NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000264159.6:c.162-6_170delinsCCAGGGGTTTGGG p.X54_splice ENST00000264159 NM_032143.2 0 +ATRX UCSF GRCh37 X 76918952 76918955 + frameshift_variant Frame_Shift_Del DEL CAGT CAGT - NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 35 0 ENST00000373344.5:c.4036_4039del p.Thr1346Ter p.T1346* ENST00000373344 NM_000489.3 1346 ACTGtg/tg 0 +CCDC99 UCSF GRCh37 5 169021488 169021488 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P13_Rec Untested WXS Illumina HiSeq 17 0 ENST00000265295.4:c.774del p.Phe258LeufsTer18 p.F258Lfs*18 ENST00000265295 NM_017785.4 258 Ttt/tt 0 +CNOT1 UCSF GRCh37 16 58612662 58612662 + missense_variant Missense_Mutation SNP T T C snp132_rs112226008 P13_Rec Untested WXS Illumina HiSeq 93 42 147 0 ENST00000317147.5:c.1525A>G p.Ile509Val p.I509V ENST00000317147 NM_016284.4 509 Att/Gtt 0 +COL12A1 UCSF GRCh37 6 75890724 75890724 + missense_variant Missense_Mutation SNP C C A NOVEL P13_Rec Untested WXS Illumina HiSeq 113 47 171 0 ENST00000322507.8:c.2095G>T p.Val699Phe p.V699F ENST00000322507 NM_004370.5 699 Gtc/Ttc 0 +CR2 UCSF GRCh37 1 207643301 207643301 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 111 40 154 0 ENST00000367058.3:c.1079G>A p.Arg360Gln p.R360Q ENST00000367058 NM_001877.4 360 cGa/cAa 0 +ELL2 UCSF GRCh37 5 95231362 95231362 + missense_variant Missense_Mutation SNP G G C NOVEL P13_Rec Untested WXS Illumina HiSeq 70 17 72 0 ENST00000237853.4:c.1559C>G p.Pro520Arg p.P520R ENST00000237853 NM_012081.5 520 cCt/cGt 0 +FGF12 UCSF GRCh37 3 191888444 191888444 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P13_Rec Untested WXS Illumina HiSeq 115 32 164 0 ENST00000454309.2:c.416A>G p.Asp139Gly p.D139G ENST00000454309 NM_021032.4 139 gAt/gGt 0 +GLTSCR1 UCSF GRCh37 19 48205548 48205548 + missense_variant Missense_Mutation SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 19 9 23 0 ENST00000396720.3:c.4559C>T p.Ala1520Val p.A1520V ENST00000396720 NM_015711.3 1520 gCg/gTg 0 +HACE1 UCSF GRCh37 6 105219151 105219151 + missense_variant Missense_Mutation SNP C C G NOVEL P13_Rec Untested WXS Illumina HiSeq 112 22 136 0 ENST00000262903.4:c.2128G>C p.Val710Leu p.V710L ENST00000262903 NM_020771.3 710 Gtt/Ctt 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G C NOVEL P13_Rec Untested WXS Illumina HiSeq 69 27 136 0 ENST00000345146.2:c.394C>G p.Arg132Gly p.R132G ENST00000345146 NM_005896.2 132 Cgt/Ggt 0 +INTU UCSF GRCh37 4 128564702 128564702 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 154 33 199 0 ENST00000335251.6:c.173G>A p.Ser58Asn p.S58N ENST00000335251 NM_015693.3 58 aGt/aAt 0 +LAMA1 UCSF GRCh37 18 6971860 6971860 + missense_variant Missense_Mutation SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 139 34 177 0 ENST00000389658.3:c.6895G>A p.Gly2299Arg p.G2299R ENST00000389658 NM_005559.3 2299 Gga/Aga 0 +LCA5L UCSF GRCh37 21 40777928 40777928 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0015 P13_Rec Untested WXS Illumina HiSeq 86 12 102 0 ENST00000288350.3:c.1893G>A p.Ser631= p.S631= ENST00000288350 631 tcG/tcA 0 +MPHOSPH10 UCSF GRCh37 2 71371569 71371571 + inframe_deletion In_Frame_Del DEL AGA AGA - NOVEL P13_Rec Untested WXS Illumina HiSeq 7 0 ENST00000244230.2:c.1465_1467del p.Glu489del p.E489del ENST00000244230 NM_005791.2 486 gcAGAa/gca 0 +MYO18B UCSF GRCh37 22 26194037 26194037 + missense_variant Missense_Mutation SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 62 13 108 0 ENST00000536101.1:c.2494C>T p.His832Tyr p.H832Y ENST00000536101 832 Cac/Tac 0 +MYO7A UCSF GRCh37 11 76905469 76905469 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 50 7 61 0 ENST00000409709.3:c.4223G>A p.Arg1408His p.R1408H ENST00000409709 NM_000260.3 1408 cGc/cAc 0 +MYO9B UCSF GRCh37 19 17311626 17311626 + synonymous_variant Silent SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 124 14 153 0 ENST00000594824.1:c.4551C>T p.Phe1517= p.F1517= ENST00000594824 1517 ttC/ttT 0 +NWD1 UCSF GRCh37 19 16872863 16872863 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 101 15 102 0 ENST00000552788.1:c.2047G>A p.Asp683Asn p.D683N ENST00000552788 683 Gac/Aac 0 +PRDM9 UCSF GRCh37 5 23510029 23510029 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 58 26 101 0 ENST00000296682.3:c.194G>A p.Gly65Asp p.G65D ENST00000296682 NM_020227.2 65 gGt/gAt 0 +PROL1 UCSF GRCh37 4 71275502 71275502 + missense_variant Missense_Mutation SNP A A G NOVEL P13_Rec Untested WXS Illumina HiSeq 133 19 168 0 ENST00000399575.2:c.457A>G p.Ile153Val p.I153V ENST00000399575 NM_021225.4 153 Atc/Gtc 0 +RBPJ UCSF GRCh37 4 26426014 26426017 + frameshift_variant Frame_Shift_Del DEL CAGA CAGA - NOVEL P13_Rec Untested WXS Illumina HiSeq 12 0 ENST00000342295.1:c.589_592delACAG p.Thr197LeufsTer8 p.T197Lfs*8 ENST00000342295 NM_005349.3 196 CAGAca/ca 0 +RIF1 UCSF GRCh37 2 152320028 152320028 + missense_variant Missense_Mutation SNP C C G NOVEL P13_Rec Untested WXS Illumina HiSeq 134 20 128 0 ENST00000243326.5:c.3994C>G p.Leu1332Val p.L1332V ENST00000243326 1332 Ctt/Gtt 0 +RPL35 UCSF GRCh37 9 127623796 127623798 + inframe_deletion In_Frame_Del DEL CTT CTT - NOVEL P13_Rec Untested WXS Illumina HiSeq 8 0 ENST00000348462.3:c.40_42del p.Lys14del p.K14del ENST00000348462 NM_007209.3 14 AAG/- 0 +SDK1 UCSF GRCh37 7 4153752 4153752 + synonymous_variant Silent SNP A A G NOVEL P13_Rec Untested WXS Illumina HiSeq 76 9 91 0 ENST00000404826.2:c.3669A>G p.Ser1223= p.S1223= ENST00000404826 NM_152744.3 1223 tcA/tcG 0 +SEMA4B UCSF GRCh37 15 90771680 90771680 + synonymous_variant Silent SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 78 27 94 0 ENST00000411539.2:c.2319C>T p.Asn773= p.N773= ENST00000411539 NM_198925.2 773 aaC/aaT 0 +SHROOM3 UCSF GRCh37 4 77675759 77675759 + stop_gained Nonsense_Mutation SNP C C T NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 64 12 101 0 ENST00000296043.6:c.4123C>T p.Arg1375Ter p.R1375* ENST00000296043 NM_020859.3 1375 Cga/Tga 0 +SLFN13 UCSF GRCh37 17 33771784 33771784 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.015,1000g2011may_all_0.0426,snp132_rs78359177 P13_Rec Untested WXS Illumina HiSeq 114 40 188 0 ENST00000285013.6:c.916G>C p.Glu306Gln p.E306Q ENST00000285013 NM_144682.5 306 Gag/Cag 0 +TP53 UCSF GRCh37 17 7579370 7579370 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 30 0 ENST00000269305.4:c.317del p.Ser106ThrfsTer17 p.S106Tfs*17 ENST00000269305 NM_001126112.2 106 aGc/ac 0 +TP53 UCSF GRCh37 17 7577515 7577516 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 8 0 ENST00000269305.4:c.766dup p.Thr256AsnfsTer8 p.T256Nfs*8 ENST00000269305 NM_001126112.2 255 -/A 0 +TTC28 UCSF GRCh37 22 28501647 28501647 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 125 63 194 0 ENST00000397906.2:c.2927C>T p.Ala976Val p.A976V ENST00000397906 NM_001145418.1 976 gCc/gTc 0 +UNC5C UCSF GRCh37 4 96163617 96163617 + missense_variant Missense_Mutation SNP C C G NOVEL P13_Rec Untested WXS Illumina HiSeq 69 11 81 0 ENST00000453304.1:c.1071G>C p.Leu357Phe p.L357F ENST00000453304 NM_003728.3 357 ttG/ttC 0 +ANKRD49 UCSF GRCh37 11 94230059 94230060 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P15_Pri Untested WXS Illumina HiSeq 6 0 ENST00000302755.4:c.208dup p.Met70AsnfsTer14 p.M70Nfs*14 ENST00000302755 67 gaa/gaAa 0 +AQP2 UCSF GRCh37 12 50344806 50344806 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 31 21 45 0 ENST00000199280.3:c.193G>A p.Ala65Thr p.A65T ENST00000199280 NM_000486.5 65 Gcc/Acc 0 +ATP2A3 UCSF GRCh37 17 3848013 3848013 + synonymous_variant Silent SNP A A C 1000g2010nov_all_0.333,1000g2011may_all_0.4766,snp132_rs1800911 P15_Pri Untested WXS Illumina HiSeq 17 7 12 0 ENST00000352011.3:c.1272T>G p.Ala424= p.A424= ENST00000352011 424 gcT/gcG 0 +C7orf41 UCSF GRCh37 7 30174773 30174773 + synonymous_variant Silent SNP C C G 1000g2010nov_all_0.152,1000g2011may_all_0.1580,snp132_rs73689406 P15_Pri Untested WXS Illumina HiSeq 11 18 9 0 ENST00000324453.8:c.21C>G p.Ala7= p.A7= ENST00000324453 NM_152793.2 7 gcC/gcG 0 +CCIN UCSF GRCh37 9 36170747 36170747 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0023 P15_Pri Untested WXS Illumina HiSeq 136 40 68 0 ENST00000335119.2:c.1248C>T p.Thr416= p.T416= ENST00000335119 NM_005893.2 416 acC/acT 0 +COL12A1 UCSF GRCh37 6 75892915 75892915 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 166 62 103 0 ENST00000322507.8:c.1742G>A p.Arg581His p.R581H ENST00000322507 NM_004370.5 581 cGc/cAc 0 +EDEM3 UCSF GRCh37 1 184692968 184692999 + coding_sequence_variant,intron_variant Frame_Shift_Ins INS TCAAGAGCTTTTCTGGCATATTCCTGTAATTT TCAAGAGCTTTTCTGGCATATTCCTGTAATTT AAAAAAGGTTTTTTGGCATATTCCTTTAATTTA NOVEL P15_Pri Untested WXS Illumina HiSeq 6 0 ENST00000318130.8:c.748-9_770delinsTAAATTAAAGGAATATGCCAAAAAACCTTTTTT *250fs* ENST00000318130 NM_025191.3 0 +FRMPD4 UCSF GRCh37 X 12734265 12734265 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 217 38 125 0 ENST00000380682.1:c.1687G>A p.Glu563Lys p.E563K ENST00000380682 NM_014728.3 563 Gaa/Aaa 0 +HIST1H4D UCSF GRCh37 6 26189132 26189132 + missense_variant Missense_Mutation SNP A A T NOVEL P15_Pri Untested WXS Illumina HiSeq 126 52 75 0 ENST00000340756.2:c.173T>A p.Val58Glu p.V58E ENST00000340756 NM_003539.3 58 gTg/gAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 90 53 57 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KCNMA1 UCSF GRCh37 10 78729786 78729786 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P15_Pri Untested WXS Illumina HiSeq 7 0 ENST00000286628.8:c.2306delA p.Lys769SerfsTer17 p.K769Sfs*17 ENST00000286628 NM_001161352.1 769 aAg/ag 0 +KRTAP5-5 UCSF GRCh37 11 1651608 1651637 + inframe_deletion In_Frame_Del DEL AAGCCTTACTGCTGCCAGTCCAGCTGCTGT AAGCCTTACTGCTGCCAGTCCAGCTGCTGT - NOVEL P15_Pri Untested WXS Illumina HiSeq 6 0 ENST00000399676.2:c.543_572del p.Tyr192_Pro201del p.Y192_P201del ENST00000399676 NM_001001480.2 180 AAGCCTTACTGCTGCCAGTCCAGCTGCTGT/- 0 +MUC5B UCSF GRCh37 11 1251743 1251743 + synonymous_variant Silent SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 9 8 20 0 ENST00000529681.1:c.1383C>T p.Thr461= p.T461= ENST00000529681 NM_002458.2 461 acC/acT 0 +NCAM1 UCSF GRCh37 11 113078099 113078102 + splice_donor_variant,coding_sequence_variant Splice_Site DEL AAGT AAGT - NOVEL P15_Pri Untested WXS Illumina HiSeq 18 0 ENST00000316851.7:c.716+2_716+5del p.X239_splice ENST00000316851 NM_181351.4 239 0 +OR6C68 UCSF GRCh37 12 55887087 55887087 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 116 24 82 0 ENST00000548615.1:c.926G>A p.Arg309His p.R309H ENST00000548615 NM_001005519.2 309 cGt/cAt 0 +PLA2G4A UCSF GRCh37 1 186948489 186948489 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Pri Untested WXS Illumina HiSeq 145 36 101 0 ENST00000367466.3:c.2003T>C p.Phe668Ser p.F668S ENST00000367466 NM_024420.2 668 tTt/tCt 0 +PLXNA1 UCSF GRCh37 3 126751380 126751380 + missense_variant Missense_Mutation SNP C C A NOVEL P15_Pri Untested WXS Illumina HiSeq 63 16 45 0 ENST00000393409.2:c.5382C>A p.Asp1794Glu p.D1794E ENST00000393409 NM_032242.3 1794 gaC/gaA 0 +PRG4 UCSF GRCh37 1 186282886 186282886 + synonymous_variant Silent SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 131 32 115 0 ENST00000445192.2:c.4191C>T p.Ser1397= p.S1397= ENST00000445192 NM_005807.3 1397 tcC/tcT 0 +PRR21 UCSF GRCh37 2 240981556 240981556 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 25 4 15 1 ENST00000408934.1:c.844G>A p.Gly282Ser p.G282S ENST00000408934 NM_001080835.1 282 Ggc/Agc 0 +PRR21 UCSF GRCh37 2 240981526 240981526 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 39 5 35 1 ENST00000408934.1:c.874C>T p.Pro292Ser p.P292S ENST00000408934 NM_001080835.1 292 Ccc/Tcc 0 +RBM19 UCSF GRCh37 12 114282578 114282578 + synonymous_variant Silent SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 53 7 40 1 ENST00000261741.5:c.2680C>T p.Leu894= p.L894= ENST00000261741 NM_016196.3 894 Ctg/Ttg 0 +SAMD9L UCSF GRCh37 7 92763519 92763519 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 195 40 144 0 ENST00000318238.4:c.1766G>A p.Arg589Gln p.R589Q ENST00000318238 NM_152703.2 589 cGa/cAa 0 +SIGLEC1 UCSF GRCh37 20 3675563 3675563 + stop_gained Nonsense_Mutation SNP C C T NOVEL P15_Pri somatic WXS Sanger Illumina HiSeq 41 20 33 0 ENST00000344754.4:c.2691G>A p.Trp897Ter p.W897* ENST00000344754 NM_023068.3 897 tgG/tgA 0 +SLCO1B3 UCSF GRCh37 12 21028267 21028267 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P15_Pri Untested WXS Illumina HiSeq 6 0 ENST00000261196.2:c.833delT p.Phe278SerfsTer22 p.F278Sfs*22 ENST00000261196 276 Ttt/tt 0 +SMARCA4 UCSF GRCh37 19 11144027 11144027 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri somatic WXS Sanger Illumina HiSeq 88 24 67 0 ENST00000344626.4:c.3608G>A p.Arg1203His p.R1203H ENST00000344626 NM_003072.3 1203 cGc/cAc 0 +SNX29 UCSF GRCh37 16 12162987 12162987 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 119 22 84 0 ENST00000566228.1:c.1317C>T p.Tyr439= p.Y439= ENST00000566228 NM_032167.3 439 taC/taT 0 +ACPT UCSF GRCh37 19 51297752 51297752 + synonymous_variant Silent SNP C C A NOVEL P15_Rec Untested WXS Illumina HiSeq 22 3 46 0 ENST00000270593.1:c.900C>A p.Gly300= p.G300= ENST00000270593 NM_033068.2 300 ggC/ggA 0 +AKAP1 UCSF GRCh37 17 55195794 55195794 + synonymous_variant Silent SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 26 28 65 0 ENST00000337714.3:c.2553G>A p.Gly851= p.G851= ENST00000337714 NM_003488.3 851 ggG/ggA 0 +AQP2 UCSF GRCh37 12 50344806 50344806 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 22 21 45 0 ENST00000199280.3:c.193G>A p.Ala65Thr p.A65T ENST00000199280 NM_000486.5 65 Gcc/Acc 0 +ATP2A3 UCSF GRCh37 17 3848013 3848013 + synonymous_variant Silent SNP A A C 1000g2010nov_all_0.333,1000g2011may_all_0.4766,snp132_rs1800911 P15_Rec Untested WXS Illumina HiSeq 9 5 12 0 ENST00000352011.3:c.1272T>G p.Ala424= p.A424= ENST00000352011 424 gcT/gcG 0 +C7orf41 UCSF GRCh37 7 30174773 30174773 + synonymous_variant Silent SNP C C G 1000g2010nov_all_0.152,1000g2011may_all_0.1580,snp132_rs73689406 P15_Rec Untested WXS Illumina HiSeq 8 7 9 0 ENST00000324453.8:c.21C>G p.Ala7= p.A7= ENST00000324453 NM_152793.2 7 gcC/gcG 0 +CANX UCSF GRCh37 5 179143236 179143236 + synonymous_variant Silent SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 61 24 77 0 ENST00000247461.4:c.852C>T p.Pro284= p.P284= ENST00000247461 NM_001746.3 284 ccC/ccT 0 +CCDC11 UCSF GRCh37 18 47753978 47753978 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 84 44 79 0 ENST00000398545.4:c.1318C>T p.Arg440Cys p.R440C ENST00000398545 NM_145020.3 440 Cgc/Tgc 0 +CCDC150 UCSF GRCh37 2 197537116 197537116 + synonymous_variant Silent SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 70 35 96 0 ENST00000389175.4:c.984G>A p.Leu328= p.L328= ENST00000389175 NM_001080539.1 328 ttG/ttA 0 +CCIN UCSF GRCh37 9 36170747 36170747 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0023 P15_Rec Untested WXS Illumina HiSeq 73 57 68 0 ENST00000335119.2:c.1248C>T p.Thr416= p.T416= ENST00000335119 NM_005893.2 416 acC/acT 0 +CIC UCSF GRCh37 19 42799063 42799065 + inframe_deletion In_Frame_Del DEL AGA AGA - NOVEL P15_Rec somatic WXS Sanger Illumina HiSeq 16 0 ENST00000575354.2:c.4550_4552del p.Lys1517del p.K1517del ENST00000575354 NM_015125.3 1516 cAGAag/cag 0 +CLEC18A UCSF GRCh37 16 69988359 69988359 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.049,1000g2011may_all_0.1101,snp132_rs2549095 P15_Rec Untested WXS Illumina HiSeq 38 5 23 1 ENST00000288040.6:c.339A>G p.Leu113= p.L113= ENST00000288040 NM_001136214.2 113 ctA/ctG 0 +COL12A1 UCSF GRCh37 6 75892915 75892915 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 87 60 103 0 ENST00000322507.8:c.1742G>A p.Arg581His p.R581H ENST00000322507 NM_004370.5 581 cGc/cAc 0 +DNAH17 UCSF GRCh37 17 76481017 76481017 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 37 20 39 0 ENST00000389840.5:c.7540G>A p.Glu2514Lys p.E2514K ENST00000389840 2514 Gag/Aag 0 +ERBB4 UCSF GRCh37 2 212248672 212248672 + missense_variant Missense_Mutation SNP C C G NOVEL P15_Rec Untested WXS Illumina HiSeq 86 66 126 0 ENST00000342788.4:c.3595G>C p.Glu1199Gln p.E1199Q ENST00000342788 NM_005235.2 1199 Gag/Cag 0 +GIMAP7 UCSF GRCh37 7 150217197 150217197 + missense_variant Missense_Mutation SNP G G T NOVEL P15_Rec Untested WXS Illumina HiSeq 74 38 111 0 ENST00000313543.4:c.135G>T p.Lys45Asn p.K45N ENST00000313543 NM_153236.3 45 aaG/aaT 0 +HERC1 UCSF GRCh37 15 63954081 63954081 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Rec Untested WXS Illumina HiSeq 154 63 133 0 ENST00000443617.2:c.9041A>G p.Asn3014Ser p.N3014S ENST00000443617 NM_003922.3 3014 aAt/aGt 0 +HIST1H4D UCSF GRCh37 6 26189132 26189132 + missense_variant Missense_Mutation SNP A A T NOVEL P15_Rec Untested WXS Illumina HiSeq 59 45 75 0 ENST00000340756.2:c.173T>A p.Val58Glu p.V58E ENST00000340756 NM_003539.3 58 gTg/gAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 52 37 57 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGSF3 UCSF GRCh37 1 117146592 117146592 + missense_variant Missense_Mutation SNP C C G NOVEL P15_Rec Untested WXS Illumina HiSeq 25 4 50 0 ENST00000369486.3:c.1278G>C p.Glu426Asp p.E426D ENST00000369486 NM_001007237.2 426 gaG/gaC 0 +KCND2 UCSF GRCh37 7 119915468 119915468 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Rec Untested WXS Illumina HiSeq 52 23 66 0 ENST00000331113.4:c.782T>C p.Val261Ala p.V261A ENST00000331113 NM_012281.2 261 gTc/gCc 0 +MLL3 UCSF GRCh37 7 151935894 151935894 + missense_variant Missense_Mutation SNP A A C NOVEL P15_Rec Untested WXS Illumina HiSeq 178 20 187 0 ENST00000262189.6:c.2550T>G p.His850Gln p.H850Q ENST00000262189 NM_170606.2 850 caT/caG 0 +NES UCSF GRCh37 1 156641394 156641394 + synonymous_variant Silent SNP A A C NOVEL P15_Rec Untested WXS Illumina HiSeq 94 51 121 0 ENST00000368223.3:c.2586T>G p.Pro862= p.P862= ENST00000368223 NM_006617.1 862 ccT/ccG 0 +PCDHB13 UCSF GRCh37 5 140595477 140595477 + synonymous_variant Silent SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 24 12 60 1 ENST00000341948.4:c.1782C>T p.Gly594= p.G594= ENST00000341948 NM_018933.2 594 ggC/ggT 0 +PLA2G4A UCSF GRCh37 1 186948489 186948489 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Rec Untested WXS Illumina HiSeq 67 42 101 0 ENST00000367466.3:c.2003T>C p.Phe668Ser p.F668S ENST00000367466 NM_024420.2 668 tTt/tCt 0 +PLS3 UCSF GRCh37 X 114869338 114869338 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Rec Untested WXS Illumina HiSeq 120 42 110 0 ENST00000355899.3:c.728T>C p.Ile243Thr p.I243T ENST00000355899 NM_005032.5 243 aTt/aCt 0 +PLXNA1 UCSF GRCh37 3 126751380 126751380 + missense_variant Missense_Mutation SNP C C A NOVEL P15_Rec Untested WXS Illumina HiSeq 35 27 45 0 ENST00000393409.2:c.5382C>A p.Asp1794Glu p.D1794E ENST00000393409 NM_032242.3 1794 gaC/gaA 0 +PRG4 UCSF GRCh37 1 186282886 186282886 + synonymous_variant Silent SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 74 73 115 0 ENST00000445192.2:c.4191C>T p.Ser1397= p.S1397= ENST00000445192 NM_005807.3 1397 tcC/tcT 0 +PSG11 UCSF GRCh37 19 43529085 43529085 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 53 20 112 0 ENST00000320078.7:c.188C>T p.Thr63Ile p.T63I ENST00000320078 NM_002785.2 63 aCt/aTt 0 +RBM19 UCSF GRCh37 12 114282578 114282578 + synonymous_variant Silent SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 22 20 40 1 ENST00000261741.5:c.2680C>T p.Leu894= p.L894= ENST00000261741 NM_016196.3 894 Ctg/Ttg 0 +SAMD9L UCSF GRCh37 7 92763519 92763519 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 84 69 144 0 ENST00000318238.4:c.1766G>A p.Arg589Gln p.R589Q ENST00000318238 NM_152703.2 589 cGa/cAa 0 +SIGLEC1 UCSF GRCh37 20 3675563 3675563 + stop_gained Nonsense_Mutation SNP C C T NOVEL P15_Rec somatic WXS Sanger Illumina HiSeq 21 17 33 0 ENST00000344754.4:c.2691G>A p.Trp897Ter p.W897* ENST00000344754 NM_023068.3 897 tgG/tgA 0 +SORD UCSF GRCh37 15 45361180 45361180 + missense_variant Missense_Mutation SNP A A T 1000g2010nov_all_0.196,1000g2011may_all_0.4705,snp132_rs1042079 P15_Rec Untested WXS Illumina HiSeq 19 5 32 1 ENST00000267814.9:c.716A>T p.Gln239Leu p.Q239L ENST00000267814 NM_003104.5 239 cAg/cTg 0 +TMEM132A UCSF GRCh37 11 60699305 60699305 + stop_gained Nonsense_Mutation SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 81 11 66 0 ENST00000453848.2:c.1161G>A p.Trp387Ter p.W387* ENST00000453848 387 tgG/tgA 0 +TMTC2 UCSF GRCh37 12 83251171 83251171 + missense_variant Missense_Mutation SNP A A G NOVEL P15_Rec Untested WXS Illumina HiSeq 47 36 68 0 ENST00000321196.3:c.466A>G p.Ile156Val p.I156V ENST00000321196 NM_152588.1 156 Att/Gtt 0 +VAV2 UCSF GRCh37 9 136662918 136662918 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 16 8 36 0 ENST00000371850.3:c.850G>A p.Gly284Arg p.G284R ENST00000371850 NM_001134398.1 284 Ggg/Agg 0 +ANKRD30B UCSF GRCh37 18 14852419 14852419 + missense_variant Missense_Mutation SNP A A T NOVEL P16_Pri Untested WXS Illumina HiSeq 35 21 102 0 ENST00000358984.4:c.4119A>T p.Glu1373Asp p.E1373D ENST00000358984 NM_001145029.1 1373 gaA/gaT 0 +ATM UCSF GRCh37 11 108159724 108159724 + missense_variant Missense_Mutation SNP A A C NOVEL P16_Pri Untested WXS Illumina HiSeq 99 12 150 0 ENST00000278616.4:c.4130A>C p.Asn1377Thr p.N1377T ENST00000278616 NM_000051.3 1377 aAt/aCt 0 +ATRX UCSF GRCh37 X 76939906 76939907 + frameshift_variant Frame_Shift_Ins INS - - TTACATGCAGTGACCAAGTCCAACAAAGGCTCTGGGTGACAAATGTAGC NOVEL P16_Pri Untested WXS Illumina HiSeq 10 0 ENST00000373344.5:c.841_842insGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAA p.Asn281SerfsTer21 p.N281Sfs*21 ENST00000373344 NM_000489.3 281 aac/aGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAAac 0 +BLMH UCSF GRCh37 17 28614922 28614922 + missense_variant Missense_Mutation SNP G G C NOVEL P16_Pri Untested WXS Illumina HiSeq 77 21 127 0 ENST00000261714.6:c.365C>G p.Ala122Gly p.A122G ENST00000261714 NM_000386.3 122 gCc/gGc 0 +C10orf12 UCSF GRCh37 10 98744566 98744566 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 52 44 165 0 ENST00000286067.2:c.3419C>T p.Thr1140Met p.T1140M ENST00000286067 NM_015652.2 1140 aCg/aTg 0 +C17orf97 UCSF GRCh37 17 263652 263652 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.1126,snp132_rs111543298 P16_Pri Untested WXS Illumina HiSeq 40 7 56 1 ENST00000360127.6:c.1018G>A p.Glu340Lys p.E340K ENST00000360127 NM_001013672.4 340 Gag/Aag 0 +CRIPAK UCSF GRCh37 4 1388817 1388817 + missense_variant Missense_Mutation SNP C C G 1000g2011may_all_0.1284 P16_Pri Untested WXS Illumina HiSeq 90 11 25 1 ENST00000324803.4:c.518C>G p.Pro173Arg p.P173R ENST00000324803 NM_175918.3 173 cCa/cGa 0 +CRIPAK UCSF GRCh37 4 1388819 1388819 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 93 13 29 1 ENST00000324803.4:c.520T>C p.Cys174Arg p.C174R ENST00000324803 NM_175918.3 174 Tgt/Cgt 0 +CT47B1 UCSF GRCh37 X 120009392 120009392 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 31 6 9 0 ENST00000371311.3:c.133A>G p.Met45Val p.M45V ENST00000371311 NM_001145718.1 45 Atg/Gtg 0 +CTPS2 UCSF GRCh37 X 16627738 16627738 + synonymous_variant Silent SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 44 36 100 0 ENST00000359276.4:c.1617G>A p.Pro539= p.P539= ENST00000359276 NM_175859.1 539 ccG/ccA 0 +CYP2D6 UCSF GRCh37 22 42524214 42524215 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P16_Pri Untested WXS Illumina HiSeq 6 0 ENST00000360608.5:c.805dup p.Arg269ProfsTer5 p.R269Pfs*5 ENST00000360608 NM_000106.5 268 -/C 0 +DIP2A UCSF GRCh37 21 47924280 47924280 + missense_variant Missense_Mutation SNP A A C NOVEL P16_Pri Untested WXS Illumina HiSeq 86 58 203 0 ENST00000417564.2:c.662A>C p.His221Pro p.H221P ENST00000417564 221 cAt/cCt 0 +EPB41L4B UCSF GRCh37 9 111979226 111979226 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 50 44 129 0 ENST00000374566.3:c.1609A>G p.Asn537Asp p.N537D ENST00000374566 NM_019114.3 537 Aac/Gac 0 +EPPK1 UCSF GRCh37 8 144940543 144940543 + synonymous_variant Silent SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 135 16 10 0 ENST00000525985.1:c.6879C>T p.Gly2293= p.G2293= ENST00000525985 NM_031308.2 2293 ggC/ggT 0 +GATA3 UCSF GRCh37 10 8115916 8115916 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 58 9 123 0 ENST00000346208.3:c.1262C>T p.Pro421Leu p.P421L ENST00000346208 421 cCg/cTg 0 +GBA3 UCSF GRCh37 4 22749378 22749378 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 93 11 235 0 ENST00000508166.1:c.746T>C p.Phe249Ser p.F249S ENST00000508166 NM_020973.4 249 tTc/tCc 0 +HLA-C UCSF GRCh37 6 31239602 31239602 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.030,1000g2011may_all_0.1058,snp132_rs1050441 P16_Pri Untested WXS Illumina HiSeq 14 3 9 0 ENST00000376228.5:c.117C>T p.Pro39= p.P39= ENST00000376228 NM_002117.5 39 ccC/ccT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 54 32 148 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIAA0319 UCSF GRCh37 6 24581174 24581174 + missense_variant Missense_Mutation SNP A A G NOVEL P16_Pri Untested WXS Illumina HiSeq 42 34 214 0 ENST00000378214.3:c.1259T>C p.Val420Ala p.V420A ENST00000378214 NM_014809.3 420 gTc/gCc 0 +KIAA1024 UCSF GRCh37 15 79748599 79748599 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 65 9 124 0 ENST00000305428.3:c.110G>A p.Arg37Gln p.R37Q ENST00000305428 NM_015206.2 37 cGg/cAg 0 +LARP7 UCSF GRCh37 4 113575231 113575231 + synonymous_variant Silent SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 51 33 114 0 ENST00000324052.6:c.1584C>T p.His528= p.H528= ENST00000324052 NM_015454.2 528 caC/caT 0 +LRCH4 UCSF GRCh37 7 100179740 100179740 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 20 19 48 0 ENST00000310300.6:c.416G>A p.Arg139Lys p.R139K ENST00000310300 NM_002319.3 139 aGg/aAg 0 +MATN3 UCSF GRCh37 2 20205936 20205936 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 64 52 153 0 ENST00000407540.3:c.359C>T p.Thr120Met p.T120M ENST00000407540 NM_002381.4 120 aCg/aTg 0 +MYCBP2 UCSF GRCh37 13 77844582 77844582 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 46 31 140 0 ENST00000357337.6:c.923A>G p.Lys308Arg p.K308R ENST00000357337 308 aAg/aGg 0 +PGBD1 UCSF GRCh37 6 28269997 28269997 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 41 40 123 0 ENST00000259883.3:c.2366C>T p.Pro789Leu p.P789L ENST00000259883 789 cCc/cTc 0 +PLD2 UCSF GRCh37 17 4722104 4722104 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 50 6 66 0 ENST00000263088.6:c.2159G>A p.Arg720His p.R720H ENST00000263088 NM_001243108.1 720 cGc/cAc 0 +RGS6 UCSF GRCh37 14 72818887 72818887 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 35 9 60 0 ENST00000553530.1:c.169C>T p.Pro57Ser p.P57S ENST00000553530 NM_004296.5 57 Ccc/Tcc 0 +SCN9A UCSF GRCh37 2 167137077 167137077 + synonymous_variant Silent SNP T T A NOVEL P16_Pri Untested WXS Illumina HiSeq 70 9 132 0 ENST00000303354.6:c.2136A>T p.Pro712= p.P712= ENST00000303354 712 ccA/ccT 0 +SLC29A4 UCSF GRCh37 7 5340228 5340228 + missense_variant Missense_Mutation SNP A A C 1000g2010nov_all_0.042 P16_Pri Untested WXS Illumina HiSeq 47 6 35 1 ENST00000297195.4:c.1385A>C p.Tyr462Ser p.Y462S ENST00000297195 NM_001040661.1 462 tAc/tCc 0 +SLC29A4 UCSF GRCh37 7 5340256 5340256 + synonymous_variant Silent SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 34 6 33 1 ENST00000297195.4:c.1413G>A p.Ala471= p.A471= ENST00000297195 NM_001040661.1 471 gcG/gcA 0 +SMARCA4 UCSF GRCh37 19 11123695 11123695 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Pri somatic WXS Sanger Illumina HiSeq 38 9 81 0 ENST00000344626.4:c.2345G>A p.Gly782Asp p.G782D ENST00000344626 NM_003072.3 782 gGc/gAc 0 +TBC1D9 UCSF GRCh37 4 141578740 141578740 + synonymous_variant Silent SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 88 25 257 0 ENST00000442267.2:c.2148A>G p.Ala716= p.A716= ENST00000442267 NM_015130.2 716 gcA/gcG 0 +TH1L UCSF GRCh37 20 57565028 57565028 + missense_variant Missense_Mutation SNP G G C NOVEL P16_Pri Untested WXS Illumina HiSeq 20 27 63 0 ENST00000602795.1:c.827G>C p.Arg276Pro p.R276P ENST00000602795 NM_198976.2 276 cGc/cCc 0 +TP53 UCSF GRCh37 17 7578535 7578535 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 3 39 44 0 ENST00000269305.4:c.395A>G p.Lys132Arg p.K132R ENST00000269305 NM_001126112.2 132 aAg/aGg 0 +TPSD1 UCSF GRCh37 16 1306346 1306346 + missense_variant Missense_Mutation SNP C C G snp132_rs3865205 P16_Pri Untested WXS Illumina HiSeq 27 9 13 0 ENST00000211076.3:c.65C>G p.Pro22Arg p.P22R ENST00000211076 NM_012217.2 22 cCg/cGg 0 +ZNF595 UCSF GRCh37 4 85996 85997 + non_coding_transcript_exon_variant RNA INS - - A NOVEL P16_Pri Untested WXS Illumina HiSeq 6 0 ENST00000380882.5:n.377dup *126* ENST00000380882 0 +ABR UCSF GRCh37 17 953786 953786 + synonymous_variant Silent SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 28 11 61 0 ENST00000302538.5:c.1650G>A p.Lys550= p.K550= ENST00000302538 NM_021962.3 550 aaG/aaA 0 +ANKRD30B UCSF GRCh37 18 14852419 14852419 + missense_variant Missense_Mutation SNP A A T NOVEL P16_Rec Untested WXS Illumina HiSeq 44 22 102 0 ENST00000358984.4:c.4119A>T p.Glu1373Asp p.E1373D ENST00000358984 NM_001145029.1 1373 gaA/gaT 0 +ATRX UCSF GRCh37 X 76939906 76939907 + frameshift_variant Frame_Shift_Ins INS - - TTACATGCAGTGACCAAGTCCAACAAAGGCTCTGGGTGACAAATGTAGC NOVEL P16_Rec Untested WXS Illumina HiSeq 6 0 ENST00000373344.5:c.841_842insGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAA p.Asn281SerfsTer21 p.N281Sfs*21 ENST00000373344 NM_000489.3 281 aac/aGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAAac 0 +C10orf12 UCSF GRCh37 10 98744566 98744566 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 58 29 165 0 ENST00000286067.2:c.3419C>T p.Thr1140Met p.T1140M ENST00000286067 NM_015652.2 1140 aCg/aTg 0 +CALN1 UCSF GRCh37 7 71252852 71252852 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 29 19 80 0 ENST00000329008.5:c.568C>T p.Arg190Trp p.R190W ENST00000329008 NM_001017440.2 190 Cgg/Tgg 0 +COL6A3 UCSF GRCh37 2 238289831 238289831 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 76 12 138 0 ENST00000295550.4:c.1624G>A p.Gly542Ser p.G542S ENST00000295550 NM_004369.3 542 Ggc/Agc 0 +CRIPAK UCSF GRCh37 4 1388817 1388817 + missense_variant Missense_Mutation SNP C C G 1000g2011may_all_0.1284 P16_Rec Untested WXS Illumina HiSeq 58 16 25 1 ENST00000324803.4:c.518C>G p.Pro173Arg p.P173R ENST00000324803 NM_175918.3 173 cCa/cGa 0 +CRIPAK UCSF GRCh37 4 1388819 1388819 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 58 16 29 1 ENST00000324803.4:c.520T>C p.Cys174Arg p.C174R ENST00000324803 NM_175918.3 174 Tgt/Cgt 0 +CTPS2 UCSF GRCh37 X 16627738 16627738 + synonymous_variant Silent SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 45 31 100 0 ENST00000359276.4:c.1617G>A p.Pro539= p.P539= ENST00000359276 NM_175859.1 539 ccG/ccA 0 +CYP2D6 UCSF GRCh37 22 42524214 42524215 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P16_Rec Untested WXS Illumina HiSeq 9 0 ENST00000360608.5:c.805dup p.Arg269ProfsTer5 p.R269Pfs*5 ENST00000360608 NM_000106.5 268 -/C 0 +DIP2A UCSF GRCh37 21 47924280 47924280 + missense_variant Missense_Mutation SNP A A C NOVEL P16_Rec Untested WXS Illumina HiSeq 84 62 203 0 ENST00000417564.2:c.662A>C p.His221Pro p.H221P ENST00000417564 221 cAt/cCt 0 +DMD UCSF GRCh37 X 31792227 31792227 + synonymous_variant Silent SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 75 15 128 0 ENST00000357033.4:c.7392C>T p.Ser2464= p.S2464= ENST00000357033 NM_004007.2 2464 tcC/tcT 0 +DUX2 UCSF GRCh37 4 190989668 190989668 + non_coding_transcript_exon_variant RNA SNP C C G 1000g2010nov_all_0.054 P16_Rec Untested WXS Illumina HiSeq 63 8 40 1 ENST00000536428.1:n.873C>G *291* ENST00000536428 0 +EPB41L4B UCSF GRCh37 9 111979226 111979226 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 60 41 129 0 ENST00000374566.3:c.1609A>G p.Asn537Asp p.N537D ENST00000374566 NM_019114.3 537 Aac/Gac 0 +EPPK1 UCSF GRCh37 8 144940543 144940543 + synonymous_variant Silent SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 46 7 10 0 ENST00000525985.1:c.6879C>T p.Gly2293= p.G2293= ENST00000525985 NM_031308.2 2293 ggC/ggT 0 +FSCB UCSF GRCh37 14 44974261 44974261 + missense_variant Missense_Mutation SNP C C A NOVEL P16_Rec Untested WXS Illumina HiSeq 14 4 51 1 ENST00000340446.4:c.1930G>T p.Ala644Ser p.A644S ENST00000340446 NM_032135.3 644 Gct/Tct 0 +GBP4 UCSF GRCh37 1 89651065 89651065 + missense_variant Missense_Mutation SNP T T A NOVEL P16_Rec Untested WXS Illumina HiSeq 96 37 176 0 ENST00000355754.6:c.1795A>T p.Ser599Cys p.S599C ENST00000355754 NM_052941.4 599 Agc/Tgc 0 +HIRIP3 UCSF GRCh37 16 30006689 30006689 + missense_variant Missense_Mutation SNP A A C NOVEL P16_Rec Untested WXS Illumina HiSeq 21 6 25 2 ENST00000279392.3:c.161T>G p.Val54Gly p.V54G ENST00000279392 NM_003609.4 54 gTg/gGg 0 +HLA-B UCSF GRCh37 6 31324104 31324104 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.092,1000g2011may_all_0.1271,snp132_rs17839985 P16_Rec Untested WXS Illumina HiSeq 18 5 26 1 ENST00000412585.2:c.459C>T p.Asp153= p.D153= ENST00000412585 NM_005514.6 153 gaC/gaT 0 +HLA-C UCSF GRCh37 6 31239602 31239602 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.030,1000g2011may_all_0.1058,snp132_rs1050441 P16_Rec Untested WXS Illumina HiSeq 8 7 9 0 ENST00000376228.5:c.117C>T p.Pro39= p.P39= ENST00000376228 NM_002117.5 39 ccC/ccT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 52 29 148 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LARP7 UCSF GRCh37 4 113575231 113575231 + synonymous_variant Silent SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 65 41 114 0 ENST00000324052.6:c.1584C>T p.His528= p.H528= ENST00000324052 NM_015454.2 528 caC/caT 0 +LRCH4 UCSF GRCh37 7 100179740 100179740 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 20 18 48 0 ENST00000310300.6:c.416G>A p.Arg139Lys p.R139K ENST00000310300 NM_002319.3 139 aGg/aAg 0 +MATN3 UCSF GRCh37 2 20205936 20205936 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 64 48 153 0 ENST00000407540.3:c.359C>T p.Thr120Met p.T120M ENST00000407540 NM_002381.4 120 aCg/aTg 0 +MGAT5 UCSF GRCh37 2 135185961 135185961 + missense_variant Missense_Mutation SNP T T G NOVEL P16_Rec Untested WXS Illumina HiSeq 49 23 120 0 ENST00000281923.2:c.1820T>G p.Phe607Cys p.F607C ENST00000281923 NM_002410.4 607 tTt/tGt 0 +MS4A6A UCSF GRCh37 11 59949075 59949075 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0028,snp132_rs113133013 P16_Rec Untested WXS Illumina HiSeq 81 46 151 0 ENST00000530839.1:c.126C>T p.His42= p.H42= ENST00000530839 NM_152852.2 42 caC/caT 0 +MYCBP2 UCSF GRCh37 13 77844582 77844582 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 37 41 140 0 ENST00000357337.6:c.923A>G p.Lys308Arg p.K308R ENST00000357337 308 aAg/aGg 0 +NAV3 UCSF GRCh37 12 78513514 78513514 + missense_variant Missense_Mutation SNP G G C NOVEL P16_Rec Untested WXS Illumina HiSeq 64 31 129 0 ENST00000397909.2:c.3538G>C p.Glu1180Gln p.E1180Q ENST00000397909 NM_001024383.1 1180 Gaa/Caa 0 +NBPF3 UCSF GRCh37 1 21806606 21806606 + missense_variant Missense_Mutation SNP T T G NOVEL P16_Rec Untested WXS Illumina HiSeq 68 8 138 1 ENST00000318249.5:c.1271T>G p.Phe424Cys p.F424C ENST00000318249 NM_032264.4 424 tTt/tGt 0 +ODZ1 UCSF GRCh37 X 124097540 124097540 + synonymous_variant Silent SNP T T A NOVEL P16_Rec Untested WXS Illumina HiSeq 152 18 247 0 ENST00000371130.3:c.63A>T p.Leu21= p.L21= ENST00000371130 NM_014253.3 21 ctA/ctT 0 +PARP3 UCSF GRCh37 3 51979175 51979175 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 38 7 97 0 ENST00000417220.2:c.796G>A p.Gly266Ser p.G266S ENST00000417220 266 Ggc/Agc 0 +PGBD1 UCSF GRCh37 6 28269997 28269997 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 54 42 123 0 ENST00000259883.3:c.2366C>T p.Pro789Leu p.P789L ENST00000259883 789 cCc/cTc 0 +PLEKHG3 UCSF GRCh37 14 65208349 65208349 + missense_variant Missense_Mutation SNP A A G NOVEL P16_Rec Untested WXS Illumina HiSeq 47 16 95 0 ENST00000394691.1:c.2114A>G p.Lys705Arg p.K705R ENST00000394691 705 aAg/aGg 0 +PLXNA3 UCSF GRCh37 X 153698095 153698095 + missense_variant Missense_Mutation SNP C C A NOVEL P16_Rec Untested WXS Illumina HiSeq 25 7 61 0 ENST00000369682.3:c.4763C>A p.Ser1588Tyr p.S1588Y ENST00000369682 NM_017514.3 1588 tCc/tAc 0 +PTPRK UCSF GRCh37 6 128385918 128385918 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 71 17 99 0 ENST00000368215.3:c.2179C>T p.Arg727Cys p.R727C ENST00000368215 727 Cgc/Tgc 0 +SLC39A12 UCSF GRCh37 10 18292136 18292136 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 131 35 172 0 ENST00000377369.2:c.1796T>C p.Met599Thr p.M599T ENST00000377369 NM_001145195.1 599 aTg/aCg 0 +TH1L UCSF GRCh37 20 57565028 57565028 + missense_variant Missense_Mutation SNP G G C NOVEL P16_Rec Untested WXS Illumina HiSeq 17 16 63 0 ENST00000602795.1:c.827G>C p.Arg276Pro p.R276P ENST00000602795 NM_198976.2 276 cGc/cCc 0 +TP53 UCSF GRCh37 17 7578535 7578535 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 6 25 44 0 ENST00000269305.4:c.395A>G p.Lys132Arg p.K132R ENST00000269305 NM_001126112.2 132 aAg/aGg 0 +TPSD1 UCSF GRCh37 16 1306346 1306346 + missense_variant Missense_Mutation SNP C C G snp132_rs3865205 P16_Rec Untested WXS Illumina HiSeq 19 14 13 0 ENST00000211076.3:c.65C>G p.Pro22Arg p.P22R ENST00000211076 NM_012217.2 22 cCg/cGg 0 +TSR1 UCSF GRCh37 17 2234404 2234404 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 78 30 124 0 ENST00000301364.5:c.1497-1G>A p.X499_splice ENST00000301364 NM_018128.4 0 +ZCCHC14 UCSF GRCh37 16 87451327 87451327 + synonymous_variant Silent SNP A A C NOVEL P16_Rec Untested WXS Illumina HiSeq 31 8 16 1 ENST00000268616.4:c.711T>G p.Gly237= p.G237= ENST00000268616 NM_015144.2 237 ggT/ggG 0 +ZNF560 UCSF GRCh37 19 9578900 9578900 + synonymous_variant Silent SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 112 16 163 0 ENST00000301480.4:c.723G>A p.Thr241= p.T241= ENST00000301480 NM_152476.2 241 acG/acA 0 +ABCA10 UCSF GRCh37 17 67170804 67170804 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Pri_A somatic WXS Sanger Illumina HiSeq 165 142 240 0 ENST00000269081.4:c.2992A>C p.Ile998Leu p.I998L ENST00000269081 NM_080282.3 998 Att/Ctt 0 +ANKRD33 UCSF GRCh37 12 52283232 52283232 + synonymous_variant Silent SNP C C A NOVEL P17_Pri_A Untested WXS Illumina HiSeq 66 59 119 1 ENST00000340970.4:c.198C>A p.Leu66= p.L66= ENST00000340970 66 ctC/ctA 0 +ATRX UCSF GRCh37 X 76937641 76937645 + frameshift_variant Frame_Shift_Del DEL TTAAT TTAAT - NOVEL P17_Pri_A Untested WXS Illumina HiSeq 105 0 ENST00000373344.5:c.3103_3107del p.Ile1035GlufsTer5 p.I1035Efs*5 ENST00000373344 NM_000489.3 1035 ATTAAg/g 0 +C7orf10 UCSF GRCh37 7 40221586 40221586 + stop_gained Nonsense_Mutation SNP T T G NOVEL P17_Pri_A Untested WXS Illumina HiSeq 67 46 93 0 ENST00000335693.4:c.206T>G p.Leu69Ter p.L69* ENST00000335693 NM_001193313.1 69 tTa/tGa 0 +CD24 UCSF GRCh37 Y 21154569 21154569 + non_coding_transcript_exon_variant RNA SNP A A G snp132_rs17855271 P17_Pri_A Untested WXS Illumina HiSeq 20 4 22 1 ENST00000382840.3:n.27T>C *9* ENST00000382840 0 +CD3EAP UCSF GRCh37 19 45911872 45911873 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P17_Pri_A Untested WXS Illumina HiSeq 18 0 ENST00000309424.3:c.653dup p.Asn218LysfsTer58 p.N218Kfs*58 ENST00000309424 NM_012099.1 216 aaa/aAaa 0 +CECR5 UCSF GRCh37 22 17619009 17619009 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Pri_A Untested WXS Illumina HiSeq 78 31 82 0 ENST00000336737.4:c.1174T>C p.Cys392Arg p.C392R ENST00000336737 NM_033070.2 392 Tgc/Cgc 0 +GPR128 UCSF GRCh37 3 100349558 100349558 + missense_variant Missense_Mutation SNP G G C NOVEL P17_Pri_A Untested WXS Illumina HiSeq 68 41 83 0 ENST00000273352.3:c.239G>C p.Cys80Ser p.C80S ENST00000273352 NM_032787.2 80 tGt/tCt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_A Untested WXS Illumina HiSeq 90 69 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LRRC16B UCSF GRCh37 14 24531921 24531921 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_A Untested WXS Illumina HiSeq 46 39 72 0 ENST00000342740.5:c.2572C>T p.Arg858Trp p.R858W ENST00000342740 NM_138360.3 858 Cgg/Tgg 0 +MED20 UCSF GRCh37 6 41875026 41875026 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P17_Pri_A somatic WXS Sanger Illumina HiSeq 59 15 47 0 ENST00000265350.4:c.424-1G>A p.X142_splice ENST00000265350 NM_004275.3 0 +NOTCH4 UCSF GRCh37 6 32170335 32170335 + missense_variant Missense_Mutation SNP G G C NOVEL P17_Pri_A Untested WXS Illumina HiSeq 22 3 33 0 ENST00000375023.3:c.3273C>G p.Cys1091Trp p.C1091W ENST00000375023 NM_004557.3 1091 tgC/tgG 0 +RFX7 UCSF GRCh37 15 56385946 56385946 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Pri_A Untested WXS Illumina HiSeq 171 140 322 0 ENST00000559447.2:c.3689A>G p.Asn1230Ser p.N1230S ENST00000559447 1230 aAt/aGt 0 +SLC4A3 UCSF GRCh37 2 220497665 220497665 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Pri_A Untested WXS Illumina HiSeq 49 10 64 0 ENST00000317151.3:c.1211T>C p.Ile404Thr p.I404T ENST00000317151 404 aTt/aCt 0 +SOX8 UCSF GRCh37 16 1035205 1035205 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Pri_A somatic WXS Sanger Illumina HiSeq 30 5 28 0 ENST00000293894.3:c.1160A>G p.Gln387Arg p.Q387R ENST00000293894 NM_014587.3 387 cAg/cGg 0 +TMEM131 UCSF GRCh37 2 98388775 98388775 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Pri_A Untested WXS Illumina HiSeq 215 174 334 0 ENST00000186436.5:c.4433C>A p.Thr1478Lys p.T1478K ENST00000186436 NM_015348.1 1478 aCa/aAa 0 +TP53 UCSF GRCh37 17 7578403 7578403 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Pri_A somatic WXS Sanger Illumina HiSeq 17 111 73 0 ENST00000269305.4:c.527G>T p.Cys176Phe p.C176F ENST00000269305 NM_001126112.2 176 tGc/tTc 0 +ZNF628 UCSF GRCh37 19 55993060 55993060 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Pri_A Untested WXS Illumina HiSeq 49 45 63 0 ENST00000598519.1:c.500G>A p.Arg167His p.R167H ENST00000598519 NM_033113.2 167 cGc/cAc 0 +ABCA10 UCSF GRCh37 17 67170804 67170804 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Pri_B somatic WXS Sanger Illumina HiSeq 172 122 240 0 ENST00000269081.4:c.2992A>C p.Ile998Leu p.I998L ENST00000269081 NM_080282.3 998 Att/Ctt 0 +ANKRD33 UCSF GRCh37 12 52283232 52283232 + synonymous_variant Silent SNP C C A NOVEL P17_Pri_B Untested WXS Illumina HiSeq 77 57 119 1 ENST00000340970.4:c.198C>A p.Leu66= p.L66= ENST00000340970 66 ctC/ctA 0 +ATRX UCSF GRCh37 X 76937641 76937645 + frameshift_variant Frame_Shift_Del DEL TTAAT TTAAT - NOVEL P17_Pri_B Untested WXS Illumina HiSeq 107 0 ENST00000373344.5:c.3103_3107del p.Ile1035GlufsTer5 p.I1035Efs*5 ENST00000373344 NM_000489.3 1035 ATTAAg/g 0 +C7orf10 UCSF GRCh37 7 40221586 40221586 + stop_gained Nonsense_Mutation SNP T T G NOVEL P17_Pri_B Untested WXS Illumina HiSeq 54 36 93 0 ENST00000335693.4:c.206T>G p.Leu69Ter p.L69* ENST00000335693 NM_001193313.1 69 tTa/tGa 0 +CD3EAP UCSF GRCh37 19 45911872 45911873 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P17_Pri_B Untested WXS Illumina HiSeq 39 0 ENST00000309424.3:c.653dup p.Asn218LysfsTer58 p.N218Kfs*58 ENST00000309424 NM_012099.1 216 aaa/aAaa 0 +CECR5 UCSF GRCh37 22 17619009 17619009 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Pri_B Untested WXS Illumina HiSeq 44 35 82 0 ENST00000336737.4:c.1174T>C p.Cys392Arg p.C392R ENST00000336737 NM_033070.2 392 Tgc/Cgc 0 +GPR128 UCSF GRCh37 3 100349558 100349558 + missense_variant Missense_Mutation SNP G G C NOVEL P17_Pri_B Untested WXS Illumina HiSeq 47 44 83 0 ENST00000273352.3:c.239G>C p.Cys80Ser p.C80S ENST00000273352 NM_032787.2 80 tGt/tCt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_B Untested WXS Illumina HiSeq 52 50 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LRRC16B UCSF GRCh37 14 24531921 24531921 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_B Untested WXS Illumina HiSeq 41 47 72 0 ENST00000342740.5:c.2572C>T p.Arg858Trp p.R858W ENST00000342740 NM_138360.3 858 Cgg/Tgg 0 +RFX7 UCSF GRCh37 15 56385946 56385946 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Pri_B Untested WXS Illumina HiSeq 251 208 322 0 ENST00000559447.2:c.3689A>G p.Asn1230Ser p.N1230S ENST00000559447 1230 aAt/aGt 0 +TMEM131 UCSF GRCh37 2 98388775 98388775 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Pri_B Untested WXS Illumina HiSeq 265 193 334 0 ENST00000186436.5:c.4433C>A p.Thr1478Lys p.T1478K ENST00000186436 NM_015348.1 1478 aCa/aAa 0 +TP53 UCSF GRCh37 17 7578403 7578403 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Pri_B somatic WXS Sanger Illumina HiSeq 17 101 73 0 ENST00000269305.4:c.527G>T p.Cys176Phe p.C176F ENST00000269305 NM_001126112.2 176 tGc/tTc 0 +ZNF628 UCSF GRCh37 19 55993060 55993060 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Pri_B Untested WXS Illumina HiSeq 48 33 63 0 ENST00000598519.1:c.500G>A p.Arg167His p.R167H ENST00000598519 NM_033113.2 167 cGc/cAc 0 +ABCA10 UCSF GRCh37 17 67170804 67170804 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Pri_C somatic WXS Sanger Illumina HiSeq 139 115 240 0 ENST00000269081.4:c.2992A>C p.Ile998Leu p.I998L ENST00000269081 NM_080282.3 998 Att/Ctt 0 +ANKRD33 UCSF GRCh37 12 52283232 52283232 + synonymous_variant Silent SNP C C A NOVEL P17_Pri_C Untested WXS Illumina HiSeq 62 57 119 1 ENST00000340970.4:c.198C>A p.Leu66= p.L66= ENST00000340970 66 ctC/ctA 0 +ATRX UCSF GRCh37 X 76937641 76937645 + frameshift_variant Frame_Shift_Del DEL TTAAT TTAAT - NOVEL P17_Pri_C Untested WXS Illumina HiSeq 105 0 ENST00000373344.5:c.3103_3107del p.Ile1035GlufsTer5 p.I1035Efs*5 ENST00000373344 NM_000489.3 1035 ATTAAg/g 0 +C7orf10 UCSF GRCh37 7 40221586 40221586 + stop_gained Nonsense_Mutation SNP T T G NOVEL P17_Pri_C Untested WXS Illumina HiSeq 44 36 93 0 ENST00000335693.4:c.206T>G p.Leu69Ter p.L69* ENST00000335693 NM_001193313.1 69 tTa/tGa 0 +CD3EAP UCSF GRCh37 19 45911872 45911873 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P17_Pri_C Untested WXS Illumina HiSeq 24 0 ENST00000309424.3:c.653dup p.Asn218LysfsTer58 p.N218Kfs*58 ENST00000309424 NM_012099.1 216 aaa/aAaa 0 +CECR5 UCSF GRCh37 22 17619009 17619009 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Pri_C Untested WXS Illumina HiSeq 48 35 82 0 ENST00000336737.4:c.1174T>C p.Cys392Arg p.C392R ENST00000336737 NM_033070.2 392 Tgc/Cgc 0 +GPR128 UCSF GRCh37 3 100349558 100349558 + missense_variant Missense_Mutation SNP G G C NOVEL P17_Pri_C Untested WXS Illumina HiSeq 42 26 83 0 ENST00000273352.3:c.239G>C p.Cys80Ser p.C80S ENST00000273352 NM_032787.2 80 tGt/tCt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_C Untested WXS Illumina HiSeq 67 48 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LRRC16B UCSF GRCh37 14 24531921 24531921 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_C Untested WXS Illumina HiSeq 57 45 72 0 ENST00000342740.5:c.2572C>T p.Arg858Trp p.R858W ENST00000342740 NM_138360.3 858 Cgg/Tgg 0 +RFX7 UCSF GRCh37 15 56385946 56385946 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Pri_C Untested WXS Illumina HiSeq 224 175 322 0 ENST00000559447.2:c.3689A>G p.Asn1230Ser p.N1230S ENST00000559447 1230 aAt/aGt 0 +TMEM131 UCSF GRCh37 2 98388775 98388775 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Pri_C Untested WXS Illumina HiSeq 276 159 334 0 ENST00000186436.5:c.4433C>A p.Thr1478Lys p.T1478K ENST00000186436 NM_015348.1 1478 aCa/aAa 0 +TP53 UCSF GRCh37 17 7578403 7578403 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Pri_C somatic WXS Sanger Illumina HiSeq 9 105 73 0 ENST00000269305.4:c.527G>T p.Cys176Phe p.C176F ENST00000269305 NM_001126112.2 176 tGc/tTc 0 +ZNF628 UCSF GRCh37 19 55993060 55993060 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Pri_C Untested WXS Illumina HiSeq 48 49 63 0 ENST00000598519.1:c.500G>A p.Arg167His p.R167H ENST00000598519 NM_033113.2 167 cGc/cAc 0 +ABCC9 UCSF GRCh37 12 21954093 21954093 + downstream_gene_variant 3'Flank SNP G G A NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 133 43 151 0 ENST00000261201 NM_005691.2 0 +ADAMTSL1 UCSF GRCh37 9 18795416 18795416 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 83 0 ENST00000380548.4:c.3700del p.Ser1234ProfsTer34 p.S1234Pfs*34 ENST00000380548 NM_001040272.5 1233 gaT/ga 0 +APLF UCSF GRCh37 2 68765111 68765111 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 149 22 118 0 ENST00000303795.4:c.912T>C p.Val304= p.V304= ENST00000303795 NM_173545.2 304 gtT/gtC 0 +ARNT UCSF GRCh37 1 150795783 150795783 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 222 46 187 0 ENST00000358595.5:c.1281C>A p.Phe427Leu p.F427L ENST00000358595 NM_178427.2 427 ttC/ttA 0 +ATP2B4 UCSF GRCh37 1 203677182 203677182 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 156 119 224 0 ENST00000357681.5:c.1507C>T p.Leu503Phe p.L503F ENST00000357681 NM_001684.4 503 Ctc/Ttc 0 +ATRX UCSF GRCh37 X 76952141 76952148 + frameshift_variant Frame_Shift_Del DEL CAAAGGTT CAAAGGTT - NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 117 0 ENST00000373344.5:c.287_294del p.Lys96ArgfsTer2 p.K96Rfs*2 ENST00000373344 NM_000489.3 96 aAACCTTTG/a 0 +BCL11B UCSF GRCh37 14 99641792 99641792 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 38 9 34 0 ENST00000357195.3:c.1381G>A p.Asp461Asn p.D461N ENST00000357195 NM_138576.2 461 Gac/Aac 0 +BRD4 UCSF GRCh37 19 15354224 15354224 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 6 11 9 0 ENST00000263377.2:c.2656C>T p.Arg886Trp p.R886W ENST00000263377 NM_058243.2 886 Cgg/Tgg 0 +C19orf2 UCSF GRCh37 19 30503247 30503247 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 229 40 210 1 ENST00000392271.1:c.1006T>C p.Ser336Pro p.S336P ENST00000392271 NM_003796.3 336 Tct/Cct 0 +CARD6 UCSF GRCh37 5 40852331 40852331 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 120 47 138 0 ENST00000254691.5:c.897A>G p.Arg299= p.R299= ENST00000254691 NM_032587.3 299 agA/agG 0 +CDHR3 UCSF GRCh37 7 105662691 105662691 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014 P17_Rec1_A Untested WXS Illumina HiSeq 317 63 338 0 ENST00000317716.9:c.1873G>A p.Val625Ile p.V625I ENST00000317716 NM_152750.4 625 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89943710 89943710 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 126 53 76 0 ENST00000320585.6:c.486T>G p.Cys162Trp p.C162W ENST00000320585 NM_012124.2 162 tgT/tgG 0 +CLTC UCSF GRCh37 17 57758404 57758404 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 229 41 208 0 ENST00000269122.3:c.3051A>G p.Val1017= p.V1017= ENST00000269122 NM_004859.3 1017 gtA/gtG 0 +CRTAP UCSF GRCh37 3 33183903 33183903 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 76 33 128 0 ENST00000320954.6:c.1169A>G p.Tyr390Cys p.Y390C ENST00000320954 NM_006371.4 390 tAt/tGt 0 +CUL4A UCSF GRCh37 13 113889388 113889388 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 130 24 111 0 ENST00000375440.4:c.777T>C p.Tyr259= p.Y259= ENST00000375440 NM_001008895.2 259 taT/taC 0 +DIDO1 UCSF GRCh37 20 61513252 61513252 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 120 98 187 0 ENST00000266070.4:c.4056C>T p.Asp1352= p.D1352= ENST00000266070 NM_033081.2 1352 gaC/gaT 0 +FAT1 UCSF GRCh37 4 187518024 187518024 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P17_Rec1_A somatic WXS Sanger Illumina HiSeq 236 65 285 0 ENST00000441802.2:c.12670G>A p.Ala4224Thr p.A4224T ENST00000441802 NM_005245.3 4224 Gct/Act 0 +FRG1 UCSF GRCh37 4 190878556 190878557 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 8 0 ENST00000226798.4:c.439dup p.Met147AsnfsTer8 p.M147Nfs*8 ENST00000226798 NM_004477.2 146 aaa/aAaa 0 +FRG1 UCSF GRCh37 4 190878542 190878571 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS GTTTCACTTAGGGGAAAATGGCTTTGTTGG GTTTCACTTAGGGGAAAATGGCTTTGTTGG TGTTTCACTTAGGGGAAAATGGCTTTGTCGA NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 6 0 ENST00000226798.4:c.433-11_451delinsTGTTTCACTTAGGGGAAAATGGCTTTGTCGA p.X145_splice ENST00000226798 NM_004477.2 0 +GPR142 UCSF GRCh37 17 72363835 72363835 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 96 13 99 0 ENST00000335666.4:c.191G>T p.Gly64Val p.G64V ENST00000335666 NM_181790.1 64 gGa/gTa 0 +HEPH UCSF GRCh37 X 65409555 65409555 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 27 102 100 0 ENST00000343002.2:c.838C>A p.Pro280Thr p.P280T ENST00000343002 280 Cct/Act 0 +HYAL4 UCSF GRCh37 7 123517035 123517035 + synonymous_variant Silent SNP A A T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 224 48 193 0 ENST00000223026.4:c.1272A>T p.Thr424= p.T424= ENST00000223026 NM_012269.2 424 acA/acT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 99 114 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL23R UCSF GRCh37 1 67724210 67724210 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 261 60 260 0 ENST00000347310.5:c.1289T>C p.Val430Ala p.V430A ENST00000347310 NM_144701.2 430 gTt/gCt 0 +KCNK15 UCSF GRCh37 20 43379023 43379023 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 70 8 60 0 ENST00000372861.3:c.537G>A p.Ser179= p.S179= ENST00000372861 NM_022358.3 179 tcG/tcA 0 +KIAA1383 UCSF GRCh37 1 232941658 232941658 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 31 17 38 0 ENST00000418460.1:c.889T>G p.Ser297Ala p.S297A ENST00000418460 NM_019090.2 297 Tcc/Gcc 0 +MDH1B UCSF GRCh37 2 207621736 207621736 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 206 29 157 0 ENST00000374412.3:c.299C>T p.Thr100Met p.T100M ENST00000374412 NM_001039845.1 100 aCg/aTg 0 +MYO7B UCSF GRCh37 2 128331590 128331590 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 200 40 194 0 ENST00000409816.2:c.688G>A p.Ala230Thr p.A230T ENST00000409816 230 Gcg/Acg 0 +PIK3CA UCSF GRCh37 3 178952085 178952085 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 134 31 156 0 ENST00000263967.3:c.3140A>G p.His1047Arg p.H1047R ENST00000263967 NM_006218.2 1047 cAt/cGt 0 +RAD54B UCSF GRCh37 8 95390425 95390425 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 49 37 71 0 ENST00000336148.5:c.2498G>A p.Gly833Glu p.G833E ENST00000336148 NM_012415.3 833 gGa/gAa 0 +SDAD1 UCSF GRCh37 4 76902575 76902575 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 153 34 100 0 ENST00000356260.5:c.244A>G p.Lys82Glu p.K82E ENST00000356260 NM_018115.2 82 Aaa/Gaa 0 +SHISA9 UCSF GRCh37 16 13010641 13010641 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 176 54 175 0 ENST00000558583.1:c.783C>T p.Asn261= p.N261= ENST00000558583 NM_001145204.2 261 aaC/aaT 0 +SHKBP1 UCSF GRCh37 19 41096697 41096697 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 61 54 94 0 ENST00000291842.5:c.1830G>A p.Pro610= p.P610= ENST00000291842 NM_138392.3 610 ccG/ccA 0 +SLC22A25 UCSF GRCh37 11 62951251 62951251 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 270 106 193 0 ENST00000306494.6:c.869A>G p.Asn290Ser p.N290S ENST00000306494 NM_199352.3 290 aAc/aGc 0 +SPAG17 UCSF GRCh37 1 118584652 118584652 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 140 104 209 0 ENST00000336338.5:c.2828A>G p.Glu943Gly p.E943G ENST00000336338 NM_206996.2 943 gAg/gGg 0 +SPTLC1 UCSF GRCh37 9 94817753 94817753 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 140 20 115 0 ENST00000262554.2:c.714T>C p.Thr238= p.T238= ENST00000262554 NM_001281303.1 238 acT/acC 0 +TMEM63B UCSF GRCh37 6 44122598 44122598 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 56 33 66 0 ENST00000259746.9:c.2477T>C p.Ile826Thr p.I826T ENST00000259746 826 aTa/aCa 0 +TP53 UCSF GRCh37 17 7578550 7578550 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 12 48 42 0 ENST00000269305.4:c.380C>T p.Ser127Phe p.S127F ENST00000269305 NM_001126112.2 127 tCc/tTc 0 +TSHB UCSF GRCh37 1 115576706 115576706 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 301 50 282 0 ENST00000256592.1:c.275C>A p.Ala92Asp p.A92D ENST00000256592 NM_000549.4 92 gCt/gAt 0 +ZNF211 UCSF GRCh37 19 58152143 58152143 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 174 33 137 0 ENST00000347302.3:c.289T>C p.Phe97Leu p.F97L ENST00000347302 NM_198855.2 97 Ttc/Ctc 0 +ABCC9 UCSF GRCh37 12 21954093 21954093 + downstream_gene_variant 3'Flank SNP G G A NOVEL P17_Rec1_B somatic WXS Sanger Illumina HiSeq 91 30 151 0 ENST00000261201 NM_005691.2 0 +ADAMTS3 UCSF GRCh37 4 73149155 73149155 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 189 54 182 0 ENST00000286657.4:c.3316A>G p.Ile1106Val p.I1106V ENST00000286657 NM_014243.2 1106 Atc/Gtc 0 +ADAMTSL1 UCSF GRCh37 9 18795416 18795416 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 67 0 ENST00000380548.4:c.3700del p.Ser1234ProfsTer34 p.S1234Pfs*34 ENST00000380548 NM_001040272.5 1233 gaT/ga 0 +ASCC2 UCSF GRCh37 22 30198032 30198032 + stop_gained Nonsense_Mutation SNP C C A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 43 7 38 0 ENST00000307790.3:c.1519G>T p.Glu507Ter p.E507* ENST00000307790 NM_032204.4 507 Gag/Tag 0 +ATP2B4 UCSF GRCh37 1 203677182 203677182 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 186 118 224 0 ENST00000357681.5:c.1507C>T p.Leu503Phe p.L503F ENST00000357681 NM_001684.4 503 Ctc/Ttc 0 +ATRX UCSF GRCh37 X 76952141 76952148 + frameshift_variant Frame_Shift_Del DEL CAAAGGTT CAAAGGTT - NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 70 0 ENST00000373344.5:c.287_294del p.Lys96ArgfsTer2 p.K96Rfs*2 ENST00000373344 NM_000489.3 96 aAACCTTTG/a 0 +AXL UCSF GRCh37 19 41727930 41727930 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_B somatic WXS Sanger Illumina HiSeq 21 6 14 0 ENST00000301178.4:c.555T>C p.Gly185= p.G185= ENST00000301178 NM_021913.4 185 ggT/ggC 0 +BCL11B UCSF GRCh37 14 99641792 99641792 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 44 10 34 0 ENST00000357195.3:c.1381G>A p.Asp461Asn p.D461N ENST00000357195 NM_138576.2 461 Gac/Aac 0 +BRD4 UCSF GRCh37 19 15354224 15354224 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 11 10 9 0 ENST00000263377.2:c.2656C>T p.Arg886Trp p.R886W ENST00000263377 NM_058243.2 886 Cgg/Tgg 0 +BRIP1 UCSF GRCh37 17 59876511 59876511 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 105 19 162 1 ENST00000259008.2:c.1290A>G p.Ile430Met p.I430M ENST00000259008 NM_032043.2 430 atA/atG 0 +CARD6 UCSF GRCh37 5 40852331 40852331 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 72 18 138 0 ENST00000254691.5:c.897A>G p.Arg299= p.R299= ENST00000254691 NM_032587.3 299 agA/agG 0 +CDHR3 UCSF GRCh37 7 105662691 105662691 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014 P17_Rec1_B Untested WXS Illumina HiSeq 404 119 338 0 ENST00000317716.9:c.1873G>A p.Val625Ile p.V625I ENST00000317716 NM_152750.4 625 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89943710 89943710 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 46 22 76 0 ENST00000320585.6:c.486T>G p.Cys162Trp p.C162W ENST00000320585 NM_012124.2 162 tgT/tgG 0 +CRTAP UCSF GRCh37 3 33183903 33183903 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 42 20 128 0 ENST00000320954.6:c.1169A>G p.Tyr390Cys p.Y390C ENST00000320954 NM_006371.4 390 tAt/tGt 0 +DIDO1 UCSF GRCh37 20 61513252 61513252 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 123 96 187 0 ENST00000266070.4:c.4056C>T p.Asp1352= p.D1352= ENST00000266070 NM_033081.2 1352 gaC/gaT 0 +DNM1L UCSF GRCh37 12 32861097 32861097 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 48 14 78 0 ENST00000549701.1:c.308A>G p.Asp103Gly p.D103G ENST00000549701 103 gAt/gGt 0 +ECI2 UCSF GRCh37 6 4133876 4133876 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 183 35 201 0 ENST00000380118.3:c.120G>A p.Gln40= p.Q40= ENST00000380118 40 caG/caA 0 +FANCA UCSF GRCh37 16 89862354 89862354 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 77 25 118 0 ENST00000389301.3:c.966T>C p.His322= p.H322= ENST00000389301 NM_000135.2 322 caT/caC 0 +FAT1 UCSF GRCh37 4 187518024 187518024 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P17_Rec1_B somatic WXS Sanger Illumina HiSeq 295 72 285 0 ENST00000441802.2:c.12670G>A p.Ala4224Thr p.A4224T ENST00000441802 NM_005245.3 4224 Gct/Act 0 +FAT1 UCSF GRCh37 4 187531037 187531037 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 242 53 246 0 ENST00000441802.2:c.9986A>G p.Asn3329Ser p.N3329S ENST00000441802 NM_005245.3 3329 aAc/aGc 0 +FLAD1 UCSF GRCh37 1 154962825 154962825 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 142 30 120 0 ENST00000292180.3:c.1375C>A p.Gln459Lys p.Q459K ENST00000292180 NM_025207.4 459 Cag/Aag 0 +GORAB UCSF GRCh37 1 170521320 170521320 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 121 33 121 0 ENST00000367763.3:c.902T>C p.Val301Ala p.V301A ENST00000367763 NM_152281.2 301 gTa/gCa 0 +HEPH UCSF GRCh37 X 65409555 65409555 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 19 97 100 0 ENST00000343002.2:c.838C>A p.Pro280Thr p.P280T ENST00000343002 280 Cct/Act 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 75 110 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KAT6B UCSF GRCh37 10 76790463 76790463 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 254 69 210 0 ENST00000287239.4:c.5881A>G p.Met1961Val p.M1961V ENST00000287239 NM_001256468.1 1961 Atg/Gtg 0 +KIAA1383 UCSF GRCh37 1 232941658 232941658 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 29 13 38 0 ENST00000418460.1:c.889T>G p.Ser297Ala p.S297A ENST00000418460 NM_019090.2 297 Tcc/Gcc 0 +MACC1 UCSF GRCh37 7 20199790 20199790 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 86 33 151 0 ENST00000332878.4:c.194A>G p.Asn65Ser p.N65S ENST00000332878 65 aAt/aGt 0 +MBD6 UCSF GRCh37 12 57921732 57921732 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 7 0 ENST00000355673.3:c.2345delG p.Gly782GlufsTer13 p.G782Efs*13 ENST00000355673 NM_052897.3 780 Ggg/gg 0 +MYO7B UCSF GRCh37 2 128331590 128331590 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 178 61 194 0 ENST00000409816.2:c.688G>A p.Ala230Thr p.A230T ENST00000409816 230 Gcg/Acg 0 +PIK3CA UCSF GRCh37 3 178952085 178952085 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B somatic WXS Sanger Illumina HiSeq 77 42 156 0 ENST00000263967.3:c.3140A>G p.His1047Arg p.H1047R ENST00000263967 NM_006218.2 1047 cAt/cGt 0 +PRKCH UCSF GRCh37 14 61788905 61788905 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 50 15 27 1 ENST00000332981.5:c.86T>C p.Leu29Pro p.L29P ENST00000332981 NM_006255.3 29 cTg/cCg 0 +RAD54B UCSF GRCh37 8 95390425 95390425 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 34 27 71 0 ENST00000336148.5:c.2498G>A p.Gly833Glu p.G833E ENST00000336148 NM_012415.3 833 gGa/gAa 0 +RGPD2 UCSF GRCh37 2 88125234 88125234 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 36 4 23 1 ENST00000398146.3:c.15A>G p.Lys5= p.K5= ENST00000398146 5 aaA/aaG 0 +SHISA9 UCSF GRCh37 16 13010641 13010641 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 136 38 175 0 ENST00000558583.1:c.783C>T p.Asn261= p.N261= ENST00000558583 NM_001145204.2 261 aaC/aaT 0 +SHKBP1 UCSF GRCh37 19 41096697 41096697 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 67 52 94 0 ENST00000291842.5:c.1830G>A p.Pro610= p.P610= ENST00000291842 NM_138392.3 610 ccG/ccA 0 +SLC22A25 UCSF GRCh37 11 62951251 62951251 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 216 102 193 0 ENST00000306494.6:c.869A>G p.Asn290Ser p.N290S ENST00000306494 NM_199352.3 290 aAc/aGc 0 +SORCS2 UCSF GRCh37 4 7691261 7691261 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 75 31 75 0 ENST00000507866.2:c.1537G>A p.Val513Ile p.V513I ENST00000507866 NM_020777.2 513 Gta/Ata 0 +SOX6 UCSF GRCh37 11 16068204 16068204 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_B somatic WXS Sanger Illumina HiSeq 63 26 100 0 ENST00000528429.1:c.1479G>A p.Gln493= p.Q493= ENST00000528429 NM_001145819.1 493 caG/caA 0 +SP6 UCSF GRCh37 17 45924768 45924768 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 22 8 22 0 ENST00000342234.2:c.1028C>T p.Ala343Val p.A343V ENST00000342234 NM_199262.2 343 gCg/gTg 0 +SPAG17 UCSF GRCh37 1 118584652 118584652 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 140 100 209 0 ENST00000336338.5:c.2828A>G p.Glu943Gly p.E943G ENST00000336338 NM_206996.2 943 gAg/gGg 0 +TLN2 UCSF GRCh37 15 63047743 63047743 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 75 30 58 0 ENST00000306829.6:c.4489G>A p.Ala1497Thr p.A1497T ENST00000306829 NM_015059.2 1497 Gcc/Acc 0 +TMEM40 UCSF GRCh37 3 12779654 12779654 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 16 7 47 0 ENST00000264728.8:c.405A>G p.Arg135= p.R135= ENST00000264728 135 agA/agG 0 +TMEM63B UCSF GRCh37 6 44122598 44122598 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 37 32 66 0 ENST00000259746.9:c.2477T>C p.Ile826Thr p.I826T ENST00000259746 826 aTa/aCa 0 +TMPRSS11B UCSF GRCh37 4 69095151 69095151 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 123 32 173 0 ENST00000332644.5:c.770T>G p.Ile257Ser p.I257S ENST00000332644 NM_182502.3 257 aTt/aGt 0 +TP53 UCSF GRCh37 17 7578550 7578550 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 3 46 42 0 ENST00000269305.4:c.380C>T p.Ser127Phe p.S127F ENST00000269305 NM_001126112.2 127 tCc/tTc 0 +TTN UCSF GRCh37 2 179641275 179641275 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 136 41 205 0 ENST00000591111.1:c.5316T>C p.Ser1772= p.S1772= ENST00000591111 1772 agT/agC 0 +UGT3A1 UCSF GRCh37 5 35965819 35965819 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 120 35 145 0 ENST00000274278.3:c.512G>T p.Gly171Val p.G171V ENST00000274278 NM_152404.3 171 gGc/gTc 0 +WFDC12 UCSF GRCh37 20 43752784 43752784 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 76 17 78 0 ENST00000372785.3:c.202T>C p.Phe68Leu p.F68L ENST00000372785 NM_080869.1 68 Ttc/Ctc 0 +ABCC9 UCSF GRCh37 12 21954093 21954093 + downstream_gene_variant 3'Flank SNP G G A NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 97 32 151 0 ENST00000261201 NM_005691.2 0 +ADAMTSL1 UCSF GRCh37 9 18795416 18795416 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 55 0 ENST00000380548.4:c.3700del p.Ser1234ProfsTer34 p.S1234Pfs*34 ENST00000380548 NM_001040272.5 1233 gaT/ga 0 +ARNT UCSF GRCh37 1 150795783 150795783 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 108 15 187 0 ENST00000358595.5:c.1281C>A p.Phe427Leu p.F427L ENST00000358595 NM_178427.2 427 ttC/ttA 0 +ATP2B4 UCSF GRCh37 1 203677182 203677182 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 165 86 224 0 ENST00000357681.5:c.1507C>T p.Leu503Phe p.L503F ENST00000357681 NM_001684.4 503 Ctc/Ttc 0 +ATRX UCSF GRCh37 X 76952141 76952148 + frameshift_variant Frame_Shift_Del DEL CAAAGGTT CAAAGGTT - NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 74 0 ENST00000373344.5:c.287_294del p.Lys96ArgfsTer2 p.K96Rfs*2 ENST00000373344 NM_000489.3 96 aAACCTTTG/a 0 +BCL11B UCSF GRCh37 14 99641792 99641792 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 25 12 34 0 ENST00000357195.3:c.1381G>A p.Asp461Asn p.D461N ENST00000357195 NM_138576.2 461 Gac/Aac 0 +BRD4 UCSF GRCh37 19 15354224 15354224 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 9 7 9 0 ENST00000263377.2:c.2656C>T p.Arg886Trp p.R886W ENST00000263377 NM_058243.2 886 Cgg/Tgg 0 +C19orf2 UCSF GRCh37 19 30503247 30503247 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 152 24 210 1 ENST00000392271.1:c.1006T>C p.Ser336Pro p.S336P ENST00000392271 NM_003796.3 336 Tct/Cct 0 +CARD6 UCSF GRCh37 5 40852331 40852331 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 69 18 138 0 ENST00000254691.5:c.897A>G p.Arg299= p.R299= ENST00000254691 NM_032587.3 299 agA/agG 0 +CDHR3 UCSF GRCh37 7 105662691 105662691 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014 P17_Rec1_C Untested WXS Illumina HiSeq 476 93 338 0 ENST00000317716.9:c.1873G>A p.Val625Ile p.V625I ENST00000317716 NM_152750.4 625 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89943710 89943710 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 49 18 76 0 ENST00000320585.6:c.486T>G p.Cys162Trp p.C162W ENST00000320585 NM_012124.2 162 tgT/tgG 0 +CLTC UCSF GRCh37 17 57758404 57758404 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 160 26 208 0 ENST00000269122.3:c.3051A>G p.Val1017= p.V1017= ENST00000269122 NM_004859.3 1017 gtA/gtG 0 +CRTAP UCSF GRCh37 3 33183903 33183903 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 54 14 128 0 ENST00000320954.6:c.1169A>G p.Tyr390Cys p.Y390C ENST00000320954 NM_006371.4 390 tAt/tGt 0 +DIDO1 UCSF GRCh37 20 61513252 61513252 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 152 82 187 0 ENST00000266070.4:c.4056C>T p.Asp1352= p.D1352= ENST00000266070 NM_033081.2 1352 gaC/gaT 0 +FAT1 UCSF GRCh37 4 187518024 187518024 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P17_Rec1_C somatic WXS Sanger Illumina HiSeq 291 87 285 0 ENST00000441802.2:c.12670G>A p.Ala4224Thr p.A4224T ENST00000441802 NM_005245.3 4224 Gct/Act 0 +HEPH UCSF GRCh37 X 65409555 65409555 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 23 76 100 0 ENST00000343002.2:c.838C>A p.Pro280Thr p.P280T ENST00000343002 280 Cct/Act 0 +HYAL4 UCSF GRCh37 7 123517035 123517035 + synonymous_variant Silent SNP A A T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 182 31 193 0 ENST00000223026.4:c.1272A>T p.Thr424= p.T424= ENST00000223026 NM_012269.2 424 acA/acT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 60 77 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL23R UCSF GRCh37 1 67724210 67724210 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 173 39 260 0 ENST00000347310.5:c.1289T>C p.Val430Ala p.V430A ENST00000347310 NM_144701.2 430 gTt/gCt 0 +KCNK15 UCSF GRCh37 20 43379023 43379023 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 123 24 60 0 ENST00000372861.3:c.537G>A p.Ser179= p.S179= ENST00000372861 NM_022358.3 179 tcG/tcA 0 +KIAA1383 UCSF GRCh37 1 232941658 232941658 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 28 17 38 0 ENST00000418460.1:c.889T>G p.Ser297Ala p.S297A ENST00000418460 NM_019090.2 297 Tcc/Gcc 0 +MDH1B UCSF GRCh37 2 207621736 207621736 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 92 14 157 0 ENST00000374412.3:c.299C>T p.Thr100Met p.T100M ENST00000374412 NM_001039845.1 100 aCg/aTg 0 +MYO7B UCSF GRCh37 2 128331590 128331590 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 180 57 194 0 ENST00000409816.2:c.688G>A p.Ala230Thr p.A230T ENST00000409816 230 Gcg/Acg 0 +PIK3CA UCSF GRCh37 3 178952085 178952085 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 88 16 156 0 ENST00000263967.3:c.3140A>G p.His1047Arg p.H1047R ENST00000263967 NM_006218.2 1047 cAt/cGt 0 +RAD54B UCSF GRCh37 8 95390425 95390425 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 40 18 71 0 ENST00000336148.5:c.2498G>A p.Gly833Glu p.G833E ENST00000336148 NM_012415.3 833 gGa/gAa 0 +SDAD1 UCSF GRCh37 4 76902575 76902575 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 72 8 100 0 ENST00000356260.5:c.244A>G p.Lys82Glu p.K82E ENST00000356260 NM_018115.2 82 Aaa/Gaa 0 +SHISA9 UCSF GRCh37 16 13010641 13010641 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 122 27 175 0 ENST00000558583.1:c.783C>T p.Asn261= p.N261= ENST00000558583 NM_001145204.2 261 aaC/aaT 0 +SHKBP1 UCSF GRCh37 19 41096697 41096697 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 64 44 94 0 ENST00000291842.5:c.1830G>A p.Pro610= p.P610= ENST00000291842 NM_138392.3 610 ccG/ccA 0 +SLC22A25 UCSF GRCh37 11 62951251 62951251 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 218 90 193 0 ENST00000306494.6:c.869A>G p.Asn290Ser p.N290S ENST00000306494 NM_199352.3 290 aAc/aGc 0 +SPAG17 UCSF GRCh37 1 118584652 118584652 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 146 87 209 0 ENST00000336338.5:c.2828A>G p.Glu943Gly p.E943G ENST00000336338 NM_206996.2 943 gAg/gGg 0 +TMEM63B UCSF GRCh37 6 44122598 44122598 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 35 24 66 0 ENST00000259746.9:c.2477T>C p.Ile826Thr p.I826T ENST00000259746 826 aTa/aCa 0 +TNFSF9 UCSF GRCh37 19 6535032 6535032 + synonymous_variant Silent SNP G G T NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 25 6 32 0 ENST00000245817.3:c.720G>T p.Val240= p.V240= ENST00000245817 NM_003811.3 240 gtG/gtT 0 +TP53 UCSF GRCh37 17 7578550 7578550 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 9 38 42 0 ENST00000269305.4:c.380C>T p.Ser127Phe p.S127F ENST00000269305 NM_001126112.2 127 tCc/tTc 0 +TSHB UCSF GRCh37 1 115576706 115576706 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 300 49 282 0 ENST00000256592.1:c.275C>A p.Ala92Asp p.A92D ENST00000256592 NM_000549.4 92 gCt/gAt 0 +ZNF211 UCSF GRCh37 19 58152143 58152143 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 130 24 137 0 ENST00000347302.3:c.289T>C p.Phe97Leu p.F97L ENST00000347302 NM_198855.2 97 Ttc/Ctc 0 +ABCC9 UCSF GRCh37 12 21954093 21954093 + downstream_gene_variant 3'Flank SNP G G A NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 86 44 151 0 ENST00000261201 NM_005691.2 0 +ADAMTS3 UCSF GRCh37 4 73149155 73149155 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 191 57 182 0 ENST00000286657.4:c.3316A>G p.Ile1106Val p.I1106V ENST00000286657 NM_014243.2 1106 Atc/Gtc 0 +ADAMTSL1 UCSF GRCh37 9 18795416 18795416 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 55 0 ENST00000380548.4:c.3700del p.Ser1234ProfsTer34 p.S1234Pfs*34 ENST00000380548 NM_001040272.5 1233 gaT/ga 0 +ASCC2 UCSF GRCh37 22 30198032 30198032 + stop_gained Nonsense_Mutation SNP C C A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 30 13 38 0 ENST00000307790.3:c.1519G>T p.Glu507Ter p.E507* ENST00000307790 NM_032204.4 507 Gag/Tag 0 +ATP2B4 UCSF GRCh37 1 203677182 203677182 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 150 122 224 0 ENST00000357681.5:c.1507C>T p.Leu503Phe p.L503F ENST00000357681 NM_001684.4 503 Ctc/Ttc 0 +ATRX UCSF GRCh37 X 76952141 76952148 + frameshift_variant Frame_Shift_Del DEL CAAAGGTT CAAAGGTT - NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 67 0 ENST00000373344.5:c.287_294del p.Lys96ArgfsTer2 p.K96Rfs*2 ENST00000373344 NM_000489.3 96 aAACCTTTG/a 0 +BCL11B UCSF GRCh37 14 99641792 99641792 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 40 12 34 0 ENST00000357195.3:c.1381G>A p.Asp461Asn p.D461N ENST00000357195 NM_138576.2 461 Gac/Aac 0 +BRD4 UCSF GRCh37 19 15354224 15354224 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 13 7 9 0 ENST00000263377.2:c.2656C>T p.Arg886Trp p.R886W ENST00000263377 NM_058243.2 886 Cgg/Tgg 0 +BRIP1 UCSF GRCh37 17 59876511 59876511 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 82 21 162 1 ENST00000259008.2:c.1290A>G p.Ile430Met p.I430M ENST00000259008 NM_032043.2 430 atA/atG 0 +CARD6 UCSF GRCh37 5 40852331 40852331 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 73 16 138 0 ENST00000254691.5:c.897A>G p.Arg299= p.R299= ENST00000254691 NM_032587.3 299 agA/agG 0 +CDHR3 UCSF GRCh37 7 105662691 105662691 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014 P17_Rec1_D Untested WXS Illumina HiSeq 424 111 338 0 ENST00000317716.9:c.1873G>A p.Val625Ile p.V625I ENST00000317716 NM_152750.4 625 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89943710 89943710 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 46 11 76 0 ENST00000320585.6:c.486T>G p.Cys162Trp p.C162W ENST00000320585 NM_012124.2 162 tgT/tgG 0 +CRTAP UCSF GRCh37 3 33183903 33183903 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 37 17 128 0 ENST00000320954.6:c.1169A>G p.Tyr390Cys p.Y390C ENST00000320954 NM_006371.4 390 tAt/tGt 0 +DIDO1 UCSF GRCh37 20 61513252 61513252 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 102 98 187 0 ENST00000266070.4:c.4056C>T p.Asp1352= p.D1352= ENST00000266070 NM_033081.2 1352 gaC/gaT 0 +DNM1L UCSF GRCh37 12 32861097 32861097 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 39 9 78 0 ENST00000549701.1:c.308A>G p.Asp103Gly p.D103G ENST00000549701 103 gAt/gGt 0 +ECI2 UCSF GRCh37 6 4133876 4133876 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 133 29 201 0 ENST00000380118.3:c.120G>A p.Gln40= p.Q40= ENST00000380118 40 caG/caA 0 +FANCA UCSF GRCh37 16 89862354 89862354 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 77 28 118 0 ENST00000389301.3:c.966T>C p.His322= p.H322= ENST00000389301 NM_000135.2 322 caT/caC 0 +FAT1 UCSF GRCh37 4 187518024 187518024 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P17_Rec1_D somatic WXS Sanger Illumina HiSeq 269 73 285 0 ENST00000441802.2:c.12670G>A p.Ala4224Thr p.A4224T ENST00000441802 NM_005245.3 4224 Gct/Act 0 +FAT1 UCSF GRCh37 4 187531037 187531037 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 248 71 246 0 ENST00000441802.2:c.9986A>G p.Asn3329Ser p.N3329S ENST00000441802 NM_005245.3 3329 aAc/aGc 0 +FGFBP1 UCSF GRCh37 4 15937919 15937919 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 163 38 192 0 ENST00000382333.1:c.337T>C p.Trp113Arg p.W113R ENST00000382333 NM_005130.4 113 Tgg/Cgg 0 +FLAD1 UCSF GRCh37 1 154962825 154962825 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 114 31 120 0 ENST00000292180.3:c.1375C>A p.Gln459Lys p.Q459K ENST00000292180 NM_025207.4 459 Cag/Aag 0 +GORAB UCSF GRCh37 1 170521320 170521320 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 113 46 121 0 ENST00000367763.3:c.902T>C p.Val301Ala p.V301A ENST00000367763 NM_152281.2 301 gTa/gCa 0 +HEPH UCSF GRCh37 X 65409555 65409555 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 9 90 100 0 ENST00000343002.2:c.838C>A p.Pro280Thr p.P280T ENST00000343002 280 Cct/Act 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 57 91 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KAT6B UCSF GRCh37 10 76790463 76790463 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 273 71 210 0 ENST00000287239.4:c.5881A>G p.Met1961Val p.M1961V ENST00000287239 NM_001256468.1 1961 Atg/Gtg 0 +KIAA1383 UCSF GRCh37 1 232941658 232941658 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 13 12 38 0 ENST00000418460.1:c.889T>G p.Ser297Ala p.S297A ENST00000418460 NM_019090.2 297 Tcc/Gcc 0 +MACC1 UCSF GRCh37 7 20199790 20199790 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 86 19 151 0 ENST00000332878.4:c.194A>G p.Asn65Ser p.N65S ENST00000332878 65 aAt/aGt 0 +MBD6 UCSF GRCh37 12 57921732 57921732 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 8 0 ENST00000355673.3:c.2345delG p.Gly782GlufsTer13 p.G782Efs*13 ENST00000355673 NM_052897.3 780 Ggg/gg 0 +MDH1B UCSF GRCh37 2 207621736 207621736 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 87 12 157 0 ENST00000374412.3:c.299C>T p.Thr100Met p.T100M ENST00000374412 NM_001039845.1 100 aCg/aTg 0 +MYO7B UCSF GRCh37 2 128331590 128331590 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 176 58 194 0 ENST00000409816.2:c.688G>A p.Ala230Thr p.A230T ENST00000409816 230 Gcg/Acg 0 +PIK3CA UCSF GRCh37 3 178952085 178952085 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 73 28 156 0 ENST00000263967.3:c.3140A>G p.His1047Arg p.H1047R ENST00000263967 NM_006218.2 1047 cAt/cGt 0 +PLEKHG1 UCSF GRCh37 6 151151933 151151933 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 132 40 163 0 ENST00000358517.2:c.1686C>T p.Phe562= p.F562= ENST00000358517 562 ttC/ttT 0 +PRKCH UCSF GRCh37 14 61788905 61788905 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 55 18 27 1 ENST00000332981.5:c.86T>C p.Leu29Pro p.L29P ENST00000332981 NM_006255.3 29 cTg/cCg 0 +RAD54B UCSF GRCh37 8 95390425 95390425 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 36 27 71 0 ENST00000336148.5:c.2498G>A p.Gly833Glu p.G833E ENST00000336148 NM_012415.3 833 gGa/gAa 0 +RGPD2 UCSF GRCh37 2 88125234 88125234 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 46 6 23 1 ENST00000398146.3:c.15A>G p.Lys5= p.K5= ENST00000398146 5 aaA/aaG 0 +SHISA9 UCSF GRCh37 16 13010641 13010641 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 114 34 175 0 ENST00000558583.1:c.783C>T p.Asn261= p.N261= ENST00000558583 NM_001145204.2 261 aaC/aaT 0 +SHKBP1 UCSF GRCh37 19 41096697 41096697 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 65 61 94 0 ENST00000291842.5:c.1830G>A p.Pro610= p.P610= ENST00000291842 NM_138392.3 610 ccG/ccA 0 +SLC22A25 UCSF GRCh37 11 62951251 62951251 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 235 94 193 0 ENST00000306494.6:c.869A>G p.Asn290Ser p.N290S ENST00000306494 NM_199352.3 290 aAc/aGc 0 +SORCS2 UCSF GRCh37 4 7691261 7691261 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 64 23 75 0 ENST00000507866.2:c.1537G>A p.Val513Ile p.V513I ENST00000507866 NM_020777.2 513 Gta/Ata 0 +SOX6 UCSF GRCh37 11 16068204 16068204 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 84 24 100 0 ENST00000528429.1:c.1479G>A p.Gln493= p.Q493= ENST00000528429 NM_001145819.1 493 caG/caA 0 +SP6 UCSF GRCh37 17 45924768 45924768 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 36 10 22 0 ENST00000342234.2:c.1028C>T p.Ala343Val p.A343V ENST00000342234 NM_199262.2 343 gCg/gTg 0 +SPAG17 UCSF GRCh37 1 118584652 118584652 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 116 93 209 0 ENST00000336338.5:c.2828A>G p.Glu943Gly p.E943G ENST00000336338 NM_206996.2 943 gAg/gGg 0 +TLN2 UCSF GRCh37 15 63047743 63047743 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 60 15 58 0 ENST00000306829.6:c.4489G>A p.Ala1497Thr p.A1497T ENST00000306829 NM_015059.2 1497 Gcc/Acc 0 +TMEM40 UCSF GRCh37 3 12779654 12779654 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 14 7 47 0 ENST00000264728.8:c.405A>G p.Arg135= p.R135= ENST00000264728 135 agA/agG 0 +TMEM63B UCSF GRCh37 6 44122598 44122598 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 34 33 66 0 ENST00000259746.9:c.2477T>C p.Ile826Thr p.I826T ENST00000259746 826 aTa/aCa 0 +TMPRSS11B UCSF GRCh37 4 69095151 69095151 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 108 32 173 0 ENST00000332644.5:c.770T>G p.Ile257Ser p.I257S ENST00000332644 NM_182502.3 257 aTt/aGt 0 +TP53 UCSF GRCh37 17 7578550 7578550 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 5 47 42 0 ENST00000269305.4:c.380C>T p.Ser127Phe p.S127F ENST00000269305 NM_001126112.2 127 tCc/tTc 0 +TTN UCSF GRCh37 2 179641275 179641275 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 119 45 205 0 ENST00000591111.1:c.5316T>C p.Ser1772= p.S1772= ENST00000591111 1772 agT/agC 0 +UGT3A1 UCSF GRCh37 5 35965819 35965819 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 114 34 145 0 ENST00000274278.3:c.512G>T p.Gly171Val p.G171V ENST00000274278 NM_152404.3 171 gGc/gTc 0 +WFDC12 UCSF GRCh37 20 43752784 43752784 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 85 25 78 0 ENST00000372785.3:c.202T>C p.Phe68Leu p.F68L ENST00000372785 NM_080869.1 68 Ttc/Ctc 0 +AATK UCSF GRCh37 17 79095911 79095911 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 13 5 23 0 ENST00000326724.4:c.1825T>C p.Ser609Pro p.S609P ENST00000326724 NM_001080395.2 609 Tct/Cct 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 106 62 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ABHD6 UCSF GRCh37 3 58255111 58255111 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 38 15 81 0 ENST00000295962.4:c.340T>C p.Ser114Pro p.S114P ENST00000295962 NM_020676.5 114 Tcc/Ccc 0 +ANKRD57 UCSF GRCh37 2 110372925 110372925 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 10 7 32 0 ENST00000356454.3:c.859C>G p.Leu287Val p.L287V ENST00000356454 NM_023016.3 287 Ctc/Gtc 0 +APOB UCSF GRCh37 2 21230912 21230912 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 143 74 265 0 ENST00000233242.1:c.8828A>G p.Glu2943Gly p.E2943G ENST00000233242 NM_000384.2 2943 gAa/gGa 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Pri_A somatic WXS Sanger Illumina HiSeq 60 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +BRAF UCSF GRCh37 7 140453136 140453136 + missense_variant Missense_Mutation SNP A A T snp132_rs113488022 P18_Pri_A somatic WXS Sanger Illumina HiSeq 143 35 190 0 ENST00000288602.6:c.1799T>A p.Val600Glu p.V600E ENST00000288602 NM_004333.4 600 gTg/gAg 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 74 63 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C6orf204 UCSF GRCh37 6 118791763 118791763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 135 62 179 0 ENST00000368491.3:c.1959G>C p.Lys653Asn p.K653N ENST00000368491 NM_001042475.2 653 aaG/aaC 0 +CACNA1A UCSF GRCh37 19 13563763 13563763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 124 92 300 0 ENST00000360228.5:c.466G>C p.Gly156Arg p.G156R ENST00000360228 NM_001127222.1 156 Ggg/Cgg 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 111 61 161 0 ENST00000381259.1:c.412A>G p.Ile138Val p.I138V ENST00000381259 NM_018318.3 138 Att/Gtt 0 +CCT8L2 UCSF GRCh37 22 17071975 17071975 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 142 67 253 0 ENST00000359963.3:c.1466C>T p.Ala489Val p.A489V ENST00000359963 NM_014406.4 489 gCc/gTc 0 +CDKAL1 UCSF GRCh37 6 21201505 21201505 + missense_variant,splice_region_variant Missense_Mutation SNP G G C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 98 39 165 0 ENST00000274695.4:c.1548G>C p.Lys516Asn p.K516N ENST00000274695 NM_017774.3 516 aaG/aaC 0 +CHRNA7 UCSF GRCh37 15 32393502 32393510 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS GAAGGATGA GAAGGATGA TTAAGGGTGG NOVEL P18_Pri_A Untested WXS Illumina HiSeq 6 0 ENST00000306901.3:c.196-4_200delinsTTAAGGGTGG p.X66_splice ENST00000306901 NM_000746.5 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 16 8 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DLEC1 UCSF GRCh37 3 38141899 38141899 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 79 34 155 0 ENST00000308059.6:c.2847G>A p.Val949= p.V949= ENST00000308059 949 gtG/gtA 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 21 95 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 78 63 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +ECEL1 UCSF GRCh37 2 233348784 233348784 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 99 11 125 2 ENST00000304546.1:c.1334C>A p.Ala445Asp p.A445D ENST00000304546 NM_004826.2 445 gCc/gAc 0 +EGF UCSF GRCh37 4 110932410 110932410 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 83 37 148 0 ENST00000265171.5:c.3423C>T p.Gly1141= p.G1141= ENST00000265171 NM_001963.4 1141 ggC/ggT 0 +ETHE1 UCSF GRCh37 19 44011007 44011007 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 94 17 94 0 ENST00000292147.2:c.760G>T p.Ala254Ser p.A254S ENST00000292147 NM_014297.3 254 Gcc/Tcc 0 +FAM189A2 UCSF GRCh37 9 71986494 71986494 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 73 51 213 0 ENST00000257515.8:c.92A>G p.Gln31Arg p.Q31R ENST00000257515 NM_004816.3 31 cAg/cGg 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 124 76 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 142 89 226 0 ENST00000356889.4:c.1599A>G p.Thr533= p.T533= ENST00000356889 NM_001287495.1 533 acA/acG 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 126 60 247 0 ENST00000295956.4:c.6231C>G p.Asp2077Glu p.D2077E ENST00000295956 NM_001457.3 2077 gaC/gaG 0 +FMN1 UCSF GRCh37 15 33261055 33261055 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 41 8 65 1 ENST00000559047.1:c.2847A>C p.Pro949= p.P949= ENST00000559047 NM_001277313.1 949 ccA/ccC 0 +GATA5 UCSF GRCh37 20 61048578 61048578 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 17 8 17 0 ENST00000252997.2:c.580G>A p.Ala194Thr p.A194T ENST00000252997 NM_080473.4 194 Gcc/Acc 0 +GMNC UCSF GRCh37 3 190578563 190578563 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 105 54 167 0 ENST00000442080.1:c.88A>T p.Ser30Cys p.S30C ENST00000442080 NM_001146686.2 30 Agt/Tgt 0 +GRM1 UCSF GRCh37 6 146755345 146755345 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 68 9 113 0 ENST00000282753.1:c.2998A>G p.Thr1000Ala p.T1000A ENST00000282753 NM_001278067.1 1000 Acc/Gcc 0 +HEATR4 UCSF GRCh37 14 73989203 73989203 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 79 17 123 0 ENST00000334988.2:c.654C>T p.Ile218= p.I218= ENST00000334988 NM_203309.2 218 atC/atT 0 +HOXC12 UCSF GRCh37 12 54350163 54350163 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 106 50 213 0 ENST00000243103.3:c.662A>G p.Tyr221Cys p.Y221C ENST00000243103 NM_173860.1 221 tAt/tGt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 67 51 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGSF10 UCSF GRCh37 3 151154586 151154586 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 104 56 197 0 ENST00000282466.3:c.7763G>T p.Gly2588Val p.G2588V ENST00000282466 NM_178822.4 2588 gGt/gTt 0 +INPPL1 UCSF GRCh37 11 71949087 71949087 + missense_variant,splice_region_variant Missense_Mutation SNP C C A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 14 7 21 0 ENST00000298229.2:c.3554C>A p.Ala1185Asp p.A1185D ENST00000298229 NM_001567.3 1185 gCt/gAt 0 +IRF2BPL UCSF GRCh37 14 77492740 77492740 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 35 10 58 0 ENST00000238647.3:c.1396C>A p.His466Asn p.H466N ENST00000238647 NM_024496.3 466 Cac/Aac 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 102 41 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +NPTN UCSF GRCh37 15 73884321 73884321 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 184 28 265 0 ENST00000345330.4:c.597C>A p.Ser199Arg p.S199R ENST00000345330 NM_012428.3 199 agC/agA 0 +NUP188 UCSF GRCh37 9 131755524 131755524 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 83 53 186 0 ENST00000372577.2:c.2689A>T p.Ile897Phe p.I897F ENST00000372577 NM_015354.2 897 Att/Ttt 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 87 47 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR51T1 UCSF GRCh37 11 4903156 4903156 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 34 71 170 0 ENST00000322049.1:c.27G>A p.Ser9= p.S9= ENST00000322049 9 tcG/tcA 0 +OR5B3 UCSF GRCh37 11 58170636 58170636 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 145 73 217 1 ENST00000309403.2:c.247T>A p.Phe83Ile p.F83I ENST00000309403 NM_001005469.1 83 Ttc/Atc 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 126 94 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +OR6C70 UCSF GRCh37 12 55863388 55863388 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 207 36 262 0 ENST00000327335.4:c.535A>G p.Ile179Val p.I179V ENST00000327335 NM_001005499.1 179 Att/Gtt 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 125 45 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PRPF40A UCSF GRCh37 2 153527822 153527822 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 146 107 242 0 ENST00000410080.1:c.1444G>A p.Glu482Lys p.E482K ENST00000410080 NM_017892.3 482 Gaa/Aaa 0 +RACGAP1 UCSF GRCh37 12 50387942 50387942 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 98 54 222 0 ENST00000312377.5:c.1311C>T p.Arg437= p.R437= ENST00000312377 437 cgC/cgT 0 +RAI14 UCSF GRCh37 5 34824590 34824590 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 69 34 110 0 ENST00000265109.3:c.2643T>C p.Asp881= p.D881= ENST00000265109 NM_015577.2 881 gaT/gaC 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 90 45 117 0 ENST00000272274.4:c.398C>T p.Ala133Val p.A133V ENST00000272274 133 gCt/gTt 0 +RYR1 UCSF GRCh37 19 38991267 38991267 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 62 14 84 0 ENST00000359596.3:c.7345G>A p.Glu2449Lys p.E2449K ENST00000359596 2449 Gag/Aag 0 +SIGLEC12 UCSF GRCh37 19 52004795 52004795 + frameshift_variant Frame_Shift_Ins INS G G CT NOVEL P18_Pri_A Untested WXS Illumina HiSeq 7 0 ENST00000291707.3:c.193delinsAG p.Ala66GlyfsTer50 p.A66Gfs*50 ENST00000291707 NM_053003.2 65 Cgg/AGgg 0 +SORT1 UCSF GRCh37 1 109890108 109890108 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 98 36 89 0 ENST00000256637.6:c.829T>A p.Cys277Ser p.C277S ENST00000256637 NM_002959.5 277 Tgc/Agc 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 94 57 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +SULT1A1 UCSF GRCh37 16 28617217 28617217 + synonymous_variant Silent SNP C C T snp132_rs11569762 P18_Pri_A Untested WXS Illumina HiSeq 67 13 101 0 ENST00000314752.7:c.813G>A p.Ala271= p.A271= ENST00000314752 NM_177529.2 271 gcG/gcA 0 +TAAR8 UCSF GRCh37 6 132874197 132874197 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 111 72 267 0 ENST00000275200.1:c.366G>T p.Leu122Phe p.L122F ENST00000275200 NM_053278.1 122 ttG/ttT 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 32 21 79 0 ENST00000541714.2:c.1372G>C p.Val458Leu p.V458L ENST00000541714 NM_001267560.1 458 Gtg/Ctg 0 +TMEM201 UCSF GRCh37 1 9658524 9658524 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 44 21 97 0 ENST00000340381.6:c.447G>T p.Glu149Asp p.E149D ENST00000340381 NM_001130924.2 149 gaG/gaT 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 110 76 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A somatic WXS Sanger Illumina HiSeq 19 50 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 101 52 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 105 48 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +TRIM59 UCSF GRCh37 3 160156368 160156369 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 6 0 ENST00000309784.4:c.604dup p.Ser202LysfsTer8 p.S202Kfs*8 ENST00000309784 NM_173084.2 201 -/A 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 114 78 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +WDR1 UCSF GRCh37 4 10089922 10089922 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 10 6 27 0 ENST00000382452.2:c.712T>G p.Tyr238Asp p.Y238D ENST00000382452 NM_017491.3 238 Tac/Gac 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 135 75 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 86 49 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +ZNF518B UCSF GRCh37 4 10445063 10445063 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 149 29 233 0 ENST00000326756.3:c.2890A>T p.Asn964Tyr p.N964Y ENST00000326756 NM_053042.2 964 Aat/Tat 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 80 31 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ADAM19 UCSF GRCh37 5 156934130 156934130 + synonymous_variant Silent SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 52 9 87 1 ENST00000517905.1:c.924C>A p.Gly308= p.G308= ENST00000517905 308 ggC/ggA 0 +ANGPT4 UCSF GRCh37 20 858877 858877 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 37 16 62 0 ENST00000381922.3:c.1147C>A p.Gln383Lys p.Q383K ENST00000381922 NM_015985.2 383 Caa/Aaa 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 19 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +C14orf49 UCSF GRCh37 14 95932381 95932381 + synonymous_variant Silent SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 106 41 119 0 ENST00000334258.5:c.514C>A p.Arg172= p.R172= ENST00000334258 NM_152592.3 172 Cgg/Agg 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 88 24 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C4BPA UCSF GRCh37 1 207317200 207317200 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 89 26 161 0 ENST00000367070.3:c.1482G>T p.Leu494Phe p.L494F ENST00000367070 NM_000715.3 494 ttG/ttT 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 106 44 161 0 ENST00000381259.1:c.412A>G p.Ile138Val p.I138V ENST00000381259 NM_018318.3 138 Att/Gtt 0 +CELA2A UCSF GRCh37 1 15789929 15789929 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 143 47 211 0 ENST00000359621.4:c.405C>A p.Asp135Glu p.D135E ENST00000359621 NM_033440.2 135 gaC/gaA 0 +CILP2 UCSF GRCh37 19 19655073 19655073 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 149 18 142 0 ENST00000291495.5:c.1719C>T p.Gly573= p.G573= ENST00000291495 NM_153221.2 573 ggC/ggT 0 +CRNN UCSF GRCh37 1 152382931 152382931 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 286 54 276 0 ENST00000271835.3:c.627G>C p.Glu209Asp p.E209D ENST00000271835 NM_016190.2 209 gaG/gaC 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 24 6 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 62 87 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 63 30 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +EFR3A UCSF GRCh37 8 132980635 132980635 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 214 38 283 0 ENST00000254624.5:c.949G>T p.Val317Phe p.V317F ENST00000254624 NM_015137.4 317 Gtt/Ttt 0 +FAM81B UCSF GRCh37 5 94731872 94731872 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 146 26 197 0 ENST00000283357.5:c.286G>T p.Val96Phe p.V96F ENST00000283357 NM_152548.2 96 Gtt/Ttt 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 222 74 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 158 72 226 0 ENST00000356889.4:c.1599A>G p.Thr533= p.T533= ENST00000356889 NM_001287495.1 533 acA/acG 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 202 59 247 0 ENST00000295956.4:c.6231C>G p.Asp2077Glu p.D2077E ENST00000295956 NM_001457.3 2077 gaC/gaG 0 +GPR158 UCSF GRCh37 10 25701295 25701295 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 304 42 301 0 ENST00000376351.3:c.1228G>A p.Val410Ile p.V410I ENST00000376351 NM_020752.2 410 Gtc/Atc 0 +GPRIN2 UCSF GRCh37 10 46999601 46999601 + missense_variant Missense_Mutation SNP G G A snp132_rs9422022 P18_Pri_B Untested WXS Illumina HiSeq 62 19 73 1 ENST00000374314.4:c.721G>A p.Val241Met p.V241M ENST00000374314 241 Gtg/Atg 0 +HOXC12 UCSF GRCh37 12 54350163 54350163 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 117 38 213 0 ENST00000243103.3:c.662A>G p.Tyr221Cys p.Y221C ENST00000243103 NM_173860.1 221 tAt/tGt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 79 33 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIAA0513 UCSF GRCh37 16 85111032 85111032 + splice_region_variant,synonymous_variant Splice_Region SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 31 7 66 0 ENST00000258180.3:c.576A>G p.Gly192= p.G192= ENST00000258180 NM_014732.2 192 ggA/ggG 0 +KRTAP4-7 UCSF GRCh37 17 39240829 39240829 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 57 10 64 0 ENST00000391417.4:c.371T>C p.Val124Ala p.V124A ENST00000391417 NM_033061.3 124 gTc/gCc 0 +LAMC2 UCSF GRCh37 1 183212454 183212454 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 119 17 161 0 ENST00000264144.4:c.3501G>C p.Leu1167= p.L1167= ENST00000264144 NM_005562.2 1167 ctG/ctC 0 +LRRIQ3 UCSF GRCh37 1 74507485 74507485 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 111 45 208 0 ENST00000354431.4:c.1130T>C p.Phe377Ser p.F377S ENST00000354431 NM_001105659.1 377 tTt/tCt 0 +LRRK1 UCSF GRCh37 15 101566207 101566207 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 52 87 118 0 ENST00000388948.3:c.2270C>T p.Thr757Met p.T757M ENST00000388948 NM_024652.3 757 aCg/aTg 0 +LTBP3 UCSF GRCh37 11 65321611 65321611 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 32 12 39 0 ENST00000301873.5:c.572T>C p.Ile191Thr p.I191T ENST00000301873 NM_001130144.2 191 aTc/aCc 0 +MAD1L1 UCSF GRCh37 7 2020096 2020096 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.015,snp132_rs113127342 P18_Pri_B Untested WXS Illumina HiSeq 15 3 35 1 ENST00000265854.7:c.1497C>T p.Asp499= p.D499= ENST00000265854 499 gaC/gaT 0 +MAGEA8 UCSF GRCh37 X 149013393 149013393 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 78 39 126 0 ENST00000286482.1:c.347T>C p.Val116Ala p.V116A ENST00000286482 NM_005364.4 116 gTg/gCg 0 +MET UCSF GRCh37 7 116339260 116339260 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 103 58 182 0 ENST00000397752.3:c.122A>G p.Tyr41Cys p.Y41C ENST00000397752 NM_000245.2 41 tAt/tGt 0 +METTL11B UCSF GRCh37 1 170135792 170135792 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 180 95 238 0 ENST00000439373.2:c.480G>A p.Gln160= p.Q160= ENST00000439373 NM_001136107.1 160 caG/caA 0 +MTUS1 UCSF GRCh37 8 17611815 17611815 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 230 117 292 0 ENST00000262102.6:c.1502G>A p.Ser501Asn p.S501N ENST00000262102 NM_001001924.2 501 aGt/aAt 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 109 60 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +NTN1 UCSF GRCh37 17 9066252 9066252 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 33 6 42 0 ENST00000173229.2:c.1141C>G p.His381Asp p.H381D ENST00000173229 NM_004822.2 381 Cat/Gat 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 159 71 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 229 104 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +PCLO UCSF GRCh37 7 82581498 82581499 + inframe_insertion In_Frame_Ins INS - - TCT NOVEL P18_Pri_B Untested WXS Illumina HiSeq 6 0 ENST00000333891.9:c.8770_8771insAGA p.Ile2923_Ile2924insLys p.I2923_I2924insK ENST00000333891 NM_033026.5 2924 ata/aAGAta 0 +PCNT UCSF GRCh37 21 47831434 47831434 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 52 8 66 1 ENST00000359568.5:c.5447C>A p.Ala1816Asp p.A1816D ENST00000359568 NM_006031.5 1816 gCc/gAc 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 126 49 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PKHD1L1 UCSF GRCh37 8 110457191 110457191 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 276 104 305 0 ENST00000378402.5:c.5093T>C p.Phe1698Ser p.F1698S ENST00000378402 NM_177531.4 1698 tTc/tCc 0 +PPP1R11 UCSF GRCh37 6 30037034 30037034 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 63 9 76 0 ENST00000376772.3:c.332C>T p.Pro111Leu p.P111L ENST00000376772 NM_021959.2 111 cCc/cTc 0 +PRR12 UCSF GRCh37 19 50100979 50100979 + synonymous_variant Silent SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 31 7 43 0 ENST00000418929.2:c.3387C>G p.Arg1129= p.R1129= ENST00000418929 NM_020719.1 1129 cgC/cgG 0 +QRFPR UCSF GRCh37 4 122257975 122257975 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 221 29 259 0 ENST00000394427.2:c.548T>C p.Val183Ala p.V183A ENST00000394427 NM_198179.2 183 gTg/gCg 0 +RAB11FIP1 UCSF GRCh37 8 37756731 37756731 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 6 8 20 0 ENST00000330843.4:c.229C>T p.Leu77= p.L77= ENST00000330843 NM_001002814.2 77 Ctg/Ttg 0 +RACGAP1 UCSF GRCh37 12 50387942 50387942 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 116 22 222 0 ENST00000312377.5:c.1311C>T p.Arg437= p.R437= ENST00000312377 437 cgC/cgT 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 53 16 117 0 ENST00000272274.4:c.398C>T p.Ala133Val p.A133V ENST00000272274 133 gCt/gTt 0 +SON UCSF GRCh37 21 34923851 34923851 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 278 41 324 0 ENST00000356577.4:c.2314G>T p.Asp772Tyr p.D772Y ENST00000356577 NM_138927.2 772 Gac/Tac 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 123 45 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +SRCAP UCSF GRCh37 16 30720835 30720835 + missense_variant,splice_region_variant Missense_Mutation SNP T T G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 76 18 111 2 ENST00000262518.4:c.635T>G p.Val212Gly p.V212G ENST00000262518 NM_006662.2 212 gTg/gGg 0 +TBL1X UCSF GRCh37 X 9652214 9652214 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 22 8 61 0 ENST00000217964.7:c.343A>G p.Ile115Val p.I115V ENST00000217964 NM_005647.3 115 Atc/Gtc 0 +TFAP2C UCSF GRCh37 20 55206427 55206427 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 37 9 59 0 ENST00000201031.2:c.215C>T p.Ser72Leu p.S72L ENST00000201031 NM_003222.3 72 tCg/tTg 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 57 26 79 0 ENST00000541714.2:c.1372G>C p.Val458Leu p.V458L ENST00000541714 NM_001267560.1 458 Gtg/Ctg 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 79 32 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 18 39 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 193 91 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 198 89 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +TTF2 UCSF GRCh37 1 117626650 117626650 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 137 47 185 0 ENST00000369466.4:c.1914C>G p.Asp638Glu p.D638E ENST00000369466 NM_003594.3 638 gaC/gaG 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 182 67 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +WWC2 UCSF GRCh37 4 184129248 184129248 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 115 42 211 0 ENST00000403733.3:c.384C>T p.Ala128= p.A128= ENST00000403733 NM_024949.5 128 gcC/gcT 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 161 26 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 60 14 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +AATK UCSF GRCh37 17 79095911 79095911 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 9 12 23 0 ENST00000326724.4:c.1825T>C p.Ser609Pro p.S609P ENST00000326724 NM_001080395.2 609 Tct/Cct 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 88 45 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ABHD6 UCSF GRCh37 3 58255111 58255111 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 54 14 81 0 ENST00000295962.4:c.340T>C p.Ser114Pro p.S114P ENST00000295962 NM_020676.5 114 Tcc/Ccc 0 +ALOX15 UCSF GRCh37 17 4542725 4542725 + missense_variant,splice_region_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.060,snp132_rs41509647 P18_Pri_C Untested WXS Illumina HiSeq 53 6 79 2 ENST00000293761.3:c.337G>A p.Gly113Ser p.G113S ENST00000293761 NM_001140.3 113 Ggc/Agc 0 +ANKRD57 UCSF GRCh37 2 110372925 110372925 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 17 22 32 0 ENST00000356454.3:c.859C>G p.Leu287Val p.L287V ENST00000356454 NM_023016.3 287 Ctc/Gtc 0 +APOB UCSF GRCh37 2 21230912 21230912 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 185 122 265 0 ENST00000233242.1:c.8828A>G p.Glu2943Gly p.E2943G ENST00000233242 NM_000384.2 2943 gAa/gGa 0 +APOBR UCSF GRCh37 16 28507445 28507445 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 11 5 32 0 ENST00000431282.1:c.1056G>C p.Glu352Asp p.E352D ENST00000431282 352 gaG/gaC 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 58 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 87 42 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C6orf204 UCSF GRCh37 6 118791763 118791763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 95 37 179 0 ENST00000368491.3:c.1959G>C p.Lys653Asn p.K653N ENST00000368491 NM_001042475.2 653 aaG/aaC 0 +CACNA1A UCSF GRCh37 19 13563763 13563763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 290 171 300 0 ENST00000360228.5:c.466G>C p.Gly156Arg p.G156R ENST00000360228 NM_001127222.1 156 Ggg/Cgg 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 89 54 161 0 ENST00000381259.1:c.412A>G p.Ile138Val p.I138V ENST00000381259 NM_018318.3 138 Att/Gtt 0 +CCT8L2 UCSF GRCh37 22 17071975 17071975 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 180 102 253 0 ENST00000359963.3:c.1466C>T p.Ala489Val p.A489V ENST00000359963 NM_014406.4 489 gCc/gTc 0 +CDKAL1 UCSF GRCh37 6 21201505 21201505 + missense_variant,splice_region_variant Missense_Mutation SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 146 25 165 0 ENST00000274695.4:c.1548G>C p.Lys516Asn p.K516N ENST00000274695 NM_017774.3 516 aaG/aaC 0 +CHRM2 UCSF GRCh37 7 136700565 136700565 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 169 34 184 0 ENST00000320658.5:c.953A>G p.Glu318Gly p.E318G ENST00000320658 NM_001006632.1 318 gAg/gGg 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 21 17 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DLEC1 UCSF GRCh37 3 38141899 38141899 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 124 22 155 0 ENST00000308059.6:c.2847G>A p.Val949= p.V949= ENST00000308059 949 gtG/gtA 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 30 125 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 83 55 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +EGF UCSF GRCh37 4 110932410 110932410 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 98 62 148 0 ENST00000265171.5:c.3423C>T p.Gly1141= p.G1141= ENST00000265171 NM_001963.4 1141 ggC/ggT 0 +F2 UCSF GRCh37 11 46751000 46751000 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 108 13 132 0 ENST00000311907.5:c.1543G>A p.Val515Ile p.V515I ENST00000311907 NM_000506.3 515 Gtt/Att 0 +FAM129A UCSF GRCh37 1 184764507 184764529 + frameshift_variant Frame_Shift_Ins INS CGGAGAGGCTGGGCTGCCTACCT CGGAGAGGCTGGGCTGCCTACCT GGGGGGGGCTGGGGTGCCCACCCC NOVEL P18_Pri_C Untested WXS Illumina HiSeq 8 0 ENST00000367511.3:c.2369_2391delinsGGGGTGGGCACCCCAGCCCCCCCC p.Glu790GlyfsTer37 p.E790Gfs*37 ENST00000367511 NM_052966.3 790 gAGGTAGGCAGCCCAGCCTCTCCG/gGGGGTGGGCACCCCAGCCCCCCCC 0 +FAM189A2 UCSF GRCh37 9 71986494 71986494 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 145 62 213 0 ENST00000257515.8:c.92A>G p.Gln31Arg p.Q31R ENST00000257515 NM_004816.3 31 cAg/cGg 0 +FAM47C UCSF GRCh37 X 37028925 37028925 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 79 14 100 0 ENST00000358047.3:c.2442G>A p.Pro814= p.P814= ENST00000358047 NM_001013736.2 814 ccG/ccA 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 214 163 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 147 110 226 0 ENST00000356889.4:c.1599A>G p.Thr533= p.T533= ENST00000356889 NM_001287495.1 533 acA/acG 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 188 104 247 0 ENST00000295956.4:c.6231C>G p.Asp2077Glu p.D2077E ENST00000295956 NM_001457.3 2077 gaC/gaG 0 +GATA5 UCSF GRCh37 20 61048578 61048578 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 10 7 17 0 ENST00000252997.2:c.580G>A p.Ala194Thr p.A194T ENST00000252997 NM_080473.4 194 Gcc/Acc 0 +GMNC UCSF GRCh37 3 190578563 190578563 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 112 80 167 0 ENST00000442080.1:c.88A>T p.Ser30Cys p.S30C ENST00000442080 NM_001146686.2 30 Agt/Tgt 0 +GP2 UCSF GRCh37 16 20337743 20337743 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 34 8 80 0 ENST00000381362.4:c.11T>G p.Leu4Arg p.L4R ENST00000381362 NM_001007240.1 4 cTt/cGt 0 +GPRIN2 UCSF GRCh37 10 46999601 46999601 + missense_variant Missense_Mutation SNP G G A snp132_rs9422022 P18_Pri_C Untested WXS Illumina HiSeq 86 20 73 1 ENST00000374314.4:c.721G>A p.Val241Met p.V241M ENST00000374314 241 Gtg/Atg 0 +HOXC12 UCSF GRCh37 12 54350163 54350163 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 116 86 213 0 ENST00000243103.3:c.662A>G p.Tyr221Cys p.Y221C ENST00000243103 NM_173860.1 221 tAt/tGt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 58 55 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFT74 UCSF GRCh37 9 26980584 26980584 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P18_Pri_C Untested WXS Illumina HiSeq 10 0 ENST00000380062.5:c.275del p.Leu92Ter p.L92* ENST00000380062 NM_025103.2 91 aTt/at 0 +IGSF10 UCSF GRCh37 3 151154586 151154586 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 180 23 197 0 ENST00000282466.3:c.7763G>T p.Gly2588Val p.G2588V ENST00000282466 NM_178822.4 2588 gGt/gTt 0 +KRAS UCSF GRCh37 12 25398220 25398220 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 32 4 45 0 ENST00000256078.4:c.99T>G p.Asp33Glu p.D33E ENST00000256078 NM_033360.2 33 gaT/gaG 0 +MKI67 UCSF GRCh37 10 129905112 129905113 + frameshift_variant Frame_Shift_Del DEL TG TG - 1000g2010nov_all P18_Pri_C Untested WXS Illumina HiSeq 7 0 ENST00000368654.3:c.4991_4992delCA p.Thr1664ArgfsTer7 p.T1664Rfs*7 ENST00000368654 NM_002417.4 1664 aCA/a 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 142 93 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +NOTCH1 UCSF GRCh37 9 139412283 139412285 + inframe_deletion In_Frame_Del DEL GTT GTT - NOVEL P18_Pri_C Untested WXS Illumina HiSeq 7 0 ENST00000277541.6:c.1360_1362delAAC p.Asn454del p.N454del ENST00000277541 NM_017617.3 454 AAC/- 0 +NUP188 UCSF GRCh37 9 131755524 131755524 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 108 57 186 0 ENST00000372577.2:c.2689A>T p.Ile897Phe p.I897F ENST00000372577 NM_015354.2 897 Att/Ttt 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 153 94 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR51T1 UCSF GRCh37 11 4903156 4903156 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 29 64 170 0 ENST00000322049.1:c.27G>A p.Ser9= p.S9= ENST00000322049 9 tcG/tcA 0 +OR5B3 UCSF GRCh37 11 58170636 58170636 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 243 32 217 1 ENST00000309403.2:c.247T>A p.Phe83Ile p.F83I ENST00000309403 NM_001005469.1 83 Ttc/Atc 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 219 160 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +OR6C70 UCSF GRCh37 12 55863388 55863388 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 255 30 262 0 ENST00000327335.4:c.535A>G p.Ile179Val p.I179V ENST00000327335 NM_001005499.1 179 Att/Gtt 0 +PAGE4 UCSF GRCh37 X 49595090 49595090 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 76 23 133 0 ENST00000218068.6:c.59A>T p.Asp20Val p.D20V ENST00000218068 NM_007003.2 20 gAt/gTt 0 +PCLO UCSF GRCh37 7 82581498 82581499 + inframe_insertion In_Frame_Ins INS - - TCT NOVEL P18_Pri_C Untested WXS Illumina HiSeq 10 0 ENST00000333891.9:c.8770_8771insAGA p.Ile2923_Ile2924insLys p.I2923_I2924insK ENST00000333891 NM_033026.5 2924 ata/aAGAta 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 174 66 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PRPF40A UCSF GRCh37 2 153527822 153527822 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 99 87 242 0 ENST00000410080.1:c.1444G>A p.Glu482Lys p.E482K ENST00000410080 NM_017892.3 482 Gaa/Aaa 0 +RACGAP1 UCSF GRCh37 12 50387942 50387942 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 119 76 222 0 ENST00000312377.5:c.1311C>T p.Arg437= p.R437= ENST00000312377 437 cgC/cgT 0 +RAF1 UCSF GRCh37 3 12645699 12645699 + missense_variant Missense_Mutation SNP G G A snp132_rs80338796 P18_Pri_C Untested WXS Illumina HiSeq 82 18 152 0 ENST00000251849.4:c.770C>T p.Ser257Leu p.S257L ENST00000251849 NM_002880.3 257 tCg/tTg 0 +RAI14 UCSF GRCh37 5 34824590 34824590 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 24 22 110 0 ENST00000265109.3:c.2643T>C p.Asp881= p.D881= ENST00000265109 NM_015577.2 881 gaT/gaC 0 +RASAL3 UCSF GRCh37 19 15567379 15567379 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 99 12 106 0 ENST00000343625.7:c.1510T>C p.Leu504= p.L504= ENST00000343625 NM_022904.1 504 Ttg/Ctg 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 53 29 117 0 ENST00000272274.4:c.398C>T p.Ala133Val p.A133V ENST00000272274 133 gCt/gTt 0 +RYR1 UCSF GRCh37 19 38991267 38991267 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 81 11 84 0 ENST00000359596.3:c.7345G>A p.Glu2449Lys p.E2449K ENST00000359596 2449 Gag/Aag 0 +SNAP91 UCSF GRCh37 6 84315432 84315432 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 33 5 54 0 ENST00000369694.2:c.1113A>C p.Pro371= p.P371= ENST00000369694 NM_001242792.1 371 ccA/ccC 0 +SORT1 UCSF GRCh37 1 109890108 109890108 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 78 26 89 0 ENST00000256637.6:c.829T>A p.Cys277Ser p.C277S ENST00000256637 NM_002959.5 277 Tgc/Agc 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 97 72 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +TAAR8 UCSF GRCh37 6 132874197 132874197 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 337 179 267 0 ENST00000275200.1:c.366G>T p.Leu122Phe p.L122F ENST00000275200 NM_053278.1 122 ttG/ttT 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 67 43 79 0 ENST00000541714.2:c.1372G>C p.Val458Leu p.V458L ENST00000541714 NM_001267560.1 458 Gtg/Ctg 0 +TLR7 UCSF GRCh37 X 12905935 12905935 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 69 11 131 0 ENST00000380659.3:c.2308A>T p.Asn770Tyr p.N770Y ENST00000380659 NM_016562.3 770 Aat/Tat 0 +TMEM201 UCSF GRCh37 1 9658524 9658524 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 45 26 97 0 ENST00000340381.6:c.447G>T p.Glu149Asp p.E149D ENST00000340381 NM_001130924.2 149 gaG/gaT 0 +TMLHE UCSF GRCh37 X 154743884 154743884 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 94 14 128 1 ENST00000334398.3:c.401T>G p.Val134Gly p.V134G ENST00000334398 NM_018196.3 134 gTg/gGg 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 89 52 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 9 66 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 185 161 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 187 166 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +TUBA3D UCSF GRCh37 2 132238306 132238306 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 193 29 160 2 ENST00000321253.6:c.1040G>T p.Cys347Phe p.C347F ENST00000321253 NM_080386.3 347 tGc/tTc 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 164 110 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +WDR1 UCSF GRCh37 4 10089922 10089922 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 17 4 27 0 ENST00000382452.2:c.712T>G p.Tyr238Asp p.Y238D ENST00000382452 NM_017491.3 238 Tac/Gac 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 161 89 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 72 41 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +AATK UCSF GRCh37 17 79095911 79095911 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 18 5 23 0 ENST00000326724.4:c.1825T>C p.Ser609Pro p.S609P ENST00000326724 NM_001080395.2 609 Tct/Cct 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 91 45 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ABHD6 UCSF GRCh37 3 58255111 58255111 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 45 18 81 0 ENST00000295962.4:c.340T>C p.Ser114Pro p.S114P ENST00000295962 NM_020676.5 114 Tcc/Ccc 0 +ANKRD57 UCSF GRCh37 2 110372925 110372925 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 30 17 32 0 ENST00000356454.3:c.859C>G p.Leu287Val p.L287V ENST00000356454 NM_023016.3 287 Ctc/Gtc 0 +APOB UCSF GRCh37 2 21230912 21230912 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 226 123 265 0 ENST00000233242.1:c.8828A>G p.Glu2943Gly p.E2943G ENST00000233242 NM_000384.2 2943 gAa/gGa 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 48 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +BCAP31 UCSF GRCh37 X 152986398 152986398 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 89 10 93 1 ENST00000345046.6:c.122T>G p.Val41Gly p.V41G ENST00000345046 NM_001256447.1 41 gTg/gGg 0 +BRAF UCSF GRCh37 7 140453136 140453136 + missense_variant Missense_Mutation SNP A A T snp132_rs113488022 P18_Pri_D somatic WXS Sanger Illumina HiSeq 159 22 190 0 ENST00000288602.6:c.1799T>A p.Val600Glu p.V600E ENST00000288602 NM_004333.4 600 gTg/gAg 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 68 39 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C6orf204 UCSF GRCh37 6 118791763 118791763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 134 53 179 0 ENST00000368491.3:c.1959G>C p.Lys653Asn p.K653N ENST00000368491 NM_001042475.2 653 aaG/aaC 0 +CACNA1A UCSF GRCh37 19 13563763 13563763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 378 193 300 0 ENST00000360228.5:c.466G>C p.Gly156Arg p.G156R ENST00000360228 NM_001127222.1 156 Ggg/Cgg 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 92 50 161 0 ENST00000381259.1:c.412A>G p.Ile138Val p.I138V ENST00000381259 NM_018318.3 138 Att/Gtt 0 +CCT8L2 UCSF GRCh37 22 17071975 17071975 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 228 117 253 0 ENST00000359963.3:c.1466C>T p.Ala489Val p.A489V ENST00000359963 NM_014406.4 489 gCc/gTc 0 +CDKAL1 UCSF GRCh37 6 21201505 21201505 + missense_variant,splice_region_variant Missense_Mutation SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 122 35 165 0 ENST00000274695.4:c.1548G>C p.Lys516Asn p.K516N ENST00000274695 NM_017774.3 516 aaG/aaC 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 27 11 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DLEC1 UCSF GRCh37 3 38141899 38141899 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 102 25 155 0 ENST00000308059.6:c.2847G>A p.Val949= p.V949= ENST00000308059 949 gtG/gtA 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 57 111 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 79 51 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +EGF UCSF GRCh37 4 110932410 110932410 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 99 28 148 0 ENST00000265171.5:c.3423C>T p.Gly1141= p.G1141= ENST00000265171 NM_001963.4 1141 ggC/ggT 0 +FAM189A2 UCSF GRCh37 9 71986494 71986494 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 166 52 213 0 ENST00000257515.8:c.92A>G p.Gln31Arg p.Q31R ENST00000257515 NM_004816.3 31 cAg/cGg 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 292 130 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 192 93 226 0 ENST00000356889.4:c.1599A>G p.Thr533= p.T533= ENST00000356889 NM_001287495.1 533 acA/acG 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 238 96 247 0 ENST00000295956.4:c.6231C>G p.Asp2077Glu p.D2077E ENST00000295956 NM_001457.3 2077 gaC/gaG 0 +GMNC UCSF GRCh37 3 190578563 190578563 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 157 67 167 0 ENST00000442080.1:c.88A>T p.Ser30Cys p.S30C ENST00000442080 NM_001146686.2 30 Agt/Tgt 0 +GPRIN2 UCSF GRCh37 10 46999601 46999601 + missense_variant Missense_Mutation SNP G G A snp132_rs9422022 P18_Pri_D Untested WXS Illumina HiSeq 89 11 73 1 ENST00000374314.4:c.721G>A p.Val241Met p.V241M ENST00000374314 241 Gtg/Atg 0 +HOXC12 UCSF GRCh37 12 54350163 54350163 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 160 71 213 0 ENST00000243103.3:c.662A>G p.Tyr221Cys p.Y221C ENST00000243103 NM_173860.1 221 tAt/tGt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 83 37 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGSF10 UCSF GRCh37 3 151154586 151154586 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 141 46 197 0 ENST00000282466.3:c.7763G>T p.Gly2588Val p.G2588V ENST00000282466 NM_178822.4 2588 gGt/gTt 0 +JUNB UCSF GRCh37 19 12903427 12903427 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 14 5 14 0 ENST00000302754.4:c.842C>G p.Ala281Gly p.A281G ENST00000302754 NM_002229.2 281 gCg/gGg 0 +MED8 UCSF GRCh37 1 43850143 43850144 + 3_prime_UTR_variant 3'UTR INS - - T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 6 0 ENST00000372457.4:c.*570dup *190* ENST00000372457 NM_201542.4 0 +MKI67 UCSF GRCh37 10 129905112 129905113 + frameshift_variant Frame_Shift_Del DEL TG TG - 1000g2010nov_all P18_Pri_D Untested WXS Illumina HiSeq 6 0 ENST00000368654.3:c.4991_4992delCA p.Thr1664ArgfsTer7 p.T1664Rfs*7 ENST00000368654 NM_002417.4 1664 aCA/a 0 +MN1 UCSF GRCh37 22 28194166 28194166 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 38 7 40 0 ENST00000302326.4:c.2366C>G p.Pro789Arg p.P789R ENST00000302326 NM_002430.2 789 cCt/cGt 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 145 72 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +NUP188 UCSF GRCh37 9 131755524 131755524 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 125 65 186 0 ENST00000372577.2:c.2689A>T p.Ile897Phe p.I897F ENST00000372577 NM_015354.2 897 Att/Ttt 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 188 105 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR51T1 UCSF GRCh37 11 4903156 4903156 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 67 73 170 0 ENST00000322049.1:c.27G>A p.Ser9= p.S9= ENST00000322049 9 tcG/tcA 0 +OR5B3 UCSF GRCh37 11 58170636 58170636 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 232 89 217 1 ENST00000309403.2:c.247T>A p.Phe83Ile p.F83I ENST00000309403 NM_001005469.1 83 Ttc/Atc 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 309 154 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +OR6C70 UCSF GRCh37 12 55863388 55863388 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 299 40 262 0 ENST00000327335.4:c.535A>G p.Ile179Val p.I179V ENST00000327335 NM_001005499.1 179 Att/Gtt 0 +OTOP1 UCSF GRCh37 4 4228243 4228243 + missense_variant Missense_Mutation SNP G G T 1000g2010nov_all_0.081 P18_Pri_D Untested WXS Illumina HiSeq 9 6 15 0 ENST00000296358.4:c.349C>A p.His117Asn p.H117N ENST00000296358 NM_177998.1 117 Cac/Aac 0 +PCDP1 UCSF GRCh37 2 120366070 120366085 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS CTCCCCAGGCAGGTGC CTCCCCAGGCAGGTGC TCTCCCCAGGCAGGGGG NOVEL P18_Pri_D Untested WXS Illumina HiSeq 6 0 ENST00000413369.3:c.1134-8_1141delinsTCTCCCCAGGCAGGGGG p.X378_splice ENST00000413369 NM_001271049.1 0 +PCLO UCSF GRCh37 7 82581498 82581499 + inframe_insertion In_Frame_Ins INS - - TCT NOVEL P18_Pri_D Untested WXS Illumina HiSeq 15 0 ENST00000333891.9:c.8770_8771insAGA p.Ile2923_Ile2924insLys p.I2923_I2924insK ENST00000333891 NM_033026.5 2924 ata/aAGAta 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 191 70 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PRPF40A UCSF GRCh37 2 153527822 153527822 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 155 53 242 0 ENST00000410080.1:c.1444G>A p.Glu482Lys p.E482K ENST00000410080 NM_017892.3 482 Gaa/Aaa 0 +RACGAP1 UCSF GRCh37 12 50387942 50387942 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 117 56 222 0 ENST00000312377.5:c.1311C>T p.Arg437= p.R437= ENST00000312377 437 cgC/cgT 0 +RAI14 UCSF GRCh37 5 34824590 34824590 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 50 24 110 0 ENST00000265109.3:c.2643T>C p.Asp881= p.D881= ENST00000265109 NM_015577.2 881 gaT/gaC 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 60 44 117 0 ENST00000272274.4:c.398C>T p.Ala133Val p.A133V ENST00000272274 133 gCt/gTt 0 +RYR1 UCSF GRCh37 19 38991267 38991267 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 78 28 84 0 ENST00000359596.3:c.7345G>A p.Glu2449Lys p.E2449K ENST00000359596 2449 Gag/Aag 0 +SORT1 UCSF GRCh37 1 109890108 109890108 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 103 27 89 0 ENST00000256637.6:c.829T>A p.Cys277Ser p.C277S ENST00000256637 NM_002959.5 277 Tgc/Agc 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 127 50 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +TAAR8 UCSF GRCh37 6 132874197 132874197 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 486 179 267 0 ENST00000275200.1:c.366G>T p.Leu122Phe p.L122F ENST00000275200 NM_053278.1 122 ttG/ttT 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 90 41 79 0 ENST00000541714.2:c.1372G>C p.Val458Leu p.V458L ENST00000541714 NM_001267560.1 458 Gtg/Ctg 0 +TMEM201 UCSF GRCh37 1 9658524 9658524 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 88 30 97 0 ENST00000340381.6:c.447G>T p.Glu149Asp p.E149D ENST00000340381 NM_001130924.2 149 gaG/gaT 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 100 50 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 17 65 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 258 84 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 257 83 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +UGT1A3 UCSF GRCh37 2 234638283 234638284 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 6 0 ENST00000482026.1:c.518dup p.Leu173PhefsTer7 p.L173Ffs*7 ENST00000482026 171 ttt/tTtt 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 226 101 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +WDR1 UCSF GRCh37 4 10089922 10089922 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 16 3 27 0 ENST00000382452.2:c.712T>G p.Tyr238Asp p.Y238D ENST00000382452 NM_017491.3 238 Tac/Gac 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 185 78 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 55 34 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +ZNF518B UCSF GRCh37 4 10445063 10445063 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 226 35 233 0 ENST00000326756.3:c.2890A>T p.Asn964Tyr p.N964Y ENST00000326756 NM_053042.2 964 Aat/Tat 0 +A1BG UCSF GRCh37 19 58862971 58862971 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 25 60 0 ENST00000263100.3:c.696C>T p.Cys232= p.C232= ENST00000263100 NM_130786.3 232 tgC/tgT 0 +A2M UCSF GRCh37 12 9229956 9229956 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 24 16 51 0 ENST00000318602.7:c.3337C>T p.Pro1113Ser p.P1113S ENST00000318602 NM_000014.4 1113 Cct/Tct 0 +AADACL4 UCSF GRCh37 1 12721866 12721866 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 81 158 0 ENST00000376221.1:c.449+1G>A p.X150_splice ENST00000376221 NM_001013630.1 0 +AARS UCSF GRCh37 16 70287616 70287616 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 35 35 75 0 ENST00000261772.8:c.2607+1G>A p.X869_splice ENST00000261772 NM_001605.2 0 +AARS2 UCSF GRCh37 6 44271120 44271120 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 44 65 0 ENST00000244571.4:c.2048C>T p.Thr683Ile p.T683I ENST00000244571 NM_020745.3 683 aCt/aTt 0 +AARSD1 UCSF GRCh37 17 41107981 41107981 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 88 192 0 ENST00000421990.2:c.1194G>A p.Lys398= p.K398= ENST00000421990 NM_001136042.2 398 aaG/aaA 0 +AASDH UCSF GRCh37 4 57204898 57204898 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 64 135 0 ENST00000205214.6:c.2967G>A p.Glu989= p.E989= ENST00000205214 NM_181806.2 989 gaG/gaA 0 +AATK UCSF GRCh37 17 79094371 79094371 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 7 17 0 ENST00000326724.4:c.3365G>A p.Gly1122Glu p.G1122E ENST00000326724 NM_001080395.2 1122 gGa/gAa 0 +ABCA1 UCSF GRCh37 9 107547874 107547874 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 81 171 0 ENST00000374736.3:c.6448C>T p.Pro2150Ser p.P2150S ENST00000374736 NM_005502.3 2150 Ccg/Tcg 0 +ABCA1 UCSF GRCh37 9 107549232 107549232 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 75 177 0 ENST00000374736.3:c.6230C>T p.Pro2077Leu p.P2077L ENST00000374736 NM_005502.3 2077 cCc/cTc 0 +ABCA12 UCSF GRCh37 2 215917211 215917211 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 49 105 0 ENST00000272895.7:c.507G>A p.Lys169= p.K169= ENST00000272895 NM_173076.2 169 aaG/aaA 0 +ABCA13 UCSF GRCh37 7 48391970 48391970 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P18_Rec Untested WXS Illumina HiSeq 64 0 ENST00000435803.1:c.10577del p.Pro3526HisfsTer5 p.P3526Hfs*5 ENST00000435803 NM_152701.3 3525 gCc/gc 0 +ABCA2 UCSF GRCh37 9 139910874 139910874 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 54 124 0 ENST00000341511.6:c.2973C>T p.Val991= p.V991= ENST00000341511 NM_212533.2 991 gtC/gtT 0 +ABCA2 UCSF GRCh37 9 139902948 139902948 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 7 10 0 ENST00000341511.6:c.7195G>A p.Glu2399Lys p.E2399K ENST00000341511 NM_212533.2 2399 Gag/Aag 0 +ABCA3 UCSF GRCh37 16 2374452 2374452 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 12 35 0 ENST00000301732.5:c.400G>A p.Val134Ile p.V134I ENST00000301732 NM_001089.2 134 Gtc/Atc 0 +ABCA3 UCSF GRCh37 16 2336836 2336836 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 59 117 0 ENST00000301732.5:c.3137C>T p.Ala1046Val p.A1046V ENST00000301732 NM_001089.2 1046 gCg/gTg 0 +ABCA3 UCSF GRCh37 16 2334326 2334326 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 140 46 75 0 ENST00000301732.5:c.3816G>A p.Arg1272= p.R1272= ENST00000301732 NM_001089.2 1272 agG/agA 0 +ABCA4 UCSF GRCh37 1 94544147 94544147 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 64 140 0 ENST00000370225.3:c.1355G>A p.Arg452Lys p.R452K ENST00000370225 NM_000350.2 452 aGa/aAa 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 63 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ABCA6 UCSF GRCh37 17 67103919 67103919 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 67 125 0 ENST00000284425.2:c.2307G>A p.Gln769= p.Q769= ENST00000284425 NM_080284.2 769 caG/caA 0 +ABCB1 UCSF GRCh37 7 87175303 87175303 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 94 217 0 ENST00000265724.3:c.1763G>A p.Arg588His p.R588H ENST00000265724 NM_000927.4 588 cGt/cAt 0 +ABCB9 UCSF GRCh37 12 123419954 123419954 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 40 73 0 ENST00000280560.8:c.1768G>A p.Val590Met p.V590M ENST00000280560 NM_019625.3 590 Gtg/Atg 0 +ABCC10 UCSF GRCh37 6 43400588 43400588 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 45 94 0 ENST00000372530.4:c.870G>A p.Leu290= p.L290= ENST00000372530 NM_001198934.1 290 ctG/ctA 0 +ABL1 UCSF GRCh37 9 133760187 133760187 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 21 46 0 ENST00000318560.5:c.2510G>A p.Gly837Glu p.G837E ENST00000318560 NM_005157.4 837 gGa/gAa 0 +ABLIM3 UCSF GRCh37 5 148620338 148620338 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 65 124 0 ENST00000309868.7:c.1303+1G>A p.X435_splice ENST00000309868 NM_014945.2 0 +ABTB2 UCSF GRCh37 11 34184228 34184228 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 28 53 0 ENST00000435224.2:c.2113G>A p.Gly705Arg p.G705R ENST00000435224 NM_145804.2 705 Ggg/Agg 0 +ACAA2 UCSF GRCh37 18 47311620 47311620 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 67 131 0 ENST00000285093.10:c.1056C>T p.His352= p.H352= ENST00000285093 NM_006111.2 352 caC/caT 0 +ACACA UCSF GRCh37 17 35545383 35545383 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 53 116 0 ENST00000353139.5:c.4610G>A p.Gly1537Glu p.G1537E ENST00000353139 NM_198834.1 1537 gGa/gAa 0 +ACACA UCSF GRCh37 17 35603853 35603853 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 164 88 210 0 ENST00000353139.5:c.2349G>A p.Glu783= p.E783= ENST00000353139 NM_198834.1 783 gaG/gaA 0 +ACAD10 UCSF GRCh37 12 112186993 112186993 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 166 111 268 0 ENST00000313698.4:c.2661C>T p.Val887= p.V887= ENST00000313698 NM_025247.5 887 gtC/gtT 0 +ACAD9 UCSF GRCh37 3 128612436 128612436 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 42 103 0 ENST00000308982.7:c.283G>A p.Asp95Asn p.D95N ENST00000308982 NM_014049.4 95 Gat/Aat 0 +ACADVL UCSF GRCh37 17 7128190 7128190 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 39 84 0 ENST00000356839.5:c.1814C>T p.Thr605Ile p.T605I ENST00000356839 NM_001270448.1 605 aCc/aTc 0 +ACAN UCSF GRCh37 15 89398830 89398830 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 65 231 0 ENST00000439576.2:c.3014C>T p.Ala1005Val p.A1005V ENST00000439576 NM_013227.3 1005 gCc/gTc 0 +ACAN UCSF GRCh37 15 89400170 89400170 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 237 147 365 0 ENST00000439576.2:c.4354C>T p.Pro1452Ser p.P1452S ENST00000439576 NM_013227.3 1452 Cct/Tct 0 +ACAN UCSF GRCh37 15 89417131 89417131 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 39 92 0 ENST00000439576.2:c.7392C>T p.Asp2464= p.D2464= ENST00000439576 NM_013227.3 2464 gaC/gaT 0 +ACAN UCSF GRCh37 15 89415235 89415235 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 98 182 0 ENST00000439576.2:c.7107C>T p.Asn2369= p.N2369= ENST00000439576 NM_013227.3 2369 aaC/aaT 0 +ACHE UCSF GRCh37 7 100490427 100490427 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 8 20 0 ENST00000241069.5:c.1081G>A p.Val361Met p.V361M ENST00000241069 NM_000665.3 361 Gtg/Atg 0 +ACO1 UCSF GRCh37 9 32427404 32427404 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 25 85 207 0 ENST00000309951.6:c.1454G>A p.Ser485Asn p.S485N ENST00000309951 NM_002197.2 485 aGc/aAc 0 +ACOT12 UCSF GRCh37 5 80626249 80626249 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 65 187 0 ENST00000307624.3:c.1632G>A p.Glu544= p.E544= ENST00000307624 NM_130767.2 544 gaG/gaA 0 +ACOT4 UCSF GRCh37 14 74061941 74061941 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 70 201 0 ENST00000326303.4:c.849G>A p.Lys283= p.K283= ENST00000326303 NM_152331.3 283 aaG/aaA 0 +ACOX2 UCSF GRCh37 3 58520818 58520818 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 143 111 259 0 ENST00000302819.5:c.16C>T p.His6Tyr p.H6Y ENST00000302819 NM_003500.3 6 Cac/Tac 0 +ACOX2 UCSF GRCh37 3 58510152 58510152 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 45 114 0 ENST00000302819.5:c.1526+1G>A p.X509_splice ENST00000302819 NM_003500.3 0 +ACOXL UCSF GRCh37 2 111551752 111551752 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 38 63 0 ENST00000389811.4:c.345+1G>A p.X115_splice ENST00000389811 0 +ACP5 UCSF GRCh37 19 11688112 11688112 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 21 44 0 ENST00000218758.5:c.21G>A p.Leu7= p.L7= ENST00000218758 NM_001111035.1 7 ctG/ctA 0 +ACP6 UCSF GRCh37 1 147122026 147122026 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 47 41 76 0 ENST00000369238.6:c.897G>A p.Met299Ile p.M299I ENST00000369238 NM_016361.4 299 atG/atA 0 +ACP6 UCSF GRCh37 1 147131086 147131086 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 99 221 0 ENST00000369238.6:c.548G>A p.Cys183Tyr p.C183Y ENST00000369238 NM_016361.4 183 tGt/tAt 0 +ACP6 UCSF GRCh37 1 147131860 147131860 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 47 108 0 ENST00000369238.6:c.250C>T p.Pro84Ser p.P84S ENST00000369238 NM_016361.4 84 Cca/Tca 0 +ACPP UCSF GRCh37 3 132068815 132068815 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 72 150 0 ENST00000336375.5:c.833C>T p.Pro278Leu p.P278L ENST00000336375 NM_001099.4 278 cCa/cTa 0 +ACSBG2 UCSF GRCh37 19 6151774 6151774 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 14 22 0 ENST00000586696.1:c.354G>A p.Trp118Ter p.W118* ENST00000586696 118 tgG/tgA 0 +ACTG1 UCSF GRCh37 17 79477785 79477785 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 75 177 0 ENST00000331925.2:c.1059G>A p.Gln353= p.Q353= ENST00000331925 NM_001614.3 353 caG/caA 0 +ACTN1 UCSF GRCh37 14 69343938 69343938 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 47 133 0 ENST00000193403.6:c.2381G>A p.Arg794His p.R794H ENST00000193403 NM_001102.3 794 cGc/cAc 0 +ACTN1 UCSF GRCh37 14 69347572 69347572 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 86 196 0 ENST00000193403.6:c.2088G>A p.Gln696= p.Q696= ENST00000193403 NM_001102.3 696 caG/caA 0 +ACTR5 UCSF GRCh37 20 37396227 37396227 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 95 187 0 ENST00000243903.4:c.1554G>A p.Arg518= p.R518= ENST00000243903 NM_024855.3 518 cgG/cgA 0 +ADAM10 UCSF GRCh37 15 58938330 58938330 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P18_Rec Untested WXS Illumina HiSeq 8 0 ENST00000260408.3:c.659del p.Asn220IlefsTer23 p.N220Ifs*23 ENST00000260408 NM_001110.2 220 aAt/at 0 +ADAM15 UCSF GRCh37 1 155028467 155028467 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 38 103 0 ENST00000356955.2:c.735G>A p.Leu245= p.L245= ENST00000356955 NM_207197.2 245 ttG/ttA 0 +ADAM2 UCSF GRCh37 8 39624683 39624683 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 163 111 225 0 ENST00000265708.4:c.1300G>A p.Glu434Lys p.E434K ENST00000265708 NM_001464.4 434 Gaa/Aaa 0 +ADAM8 UCSF GRCh37 10 135085974 135085974 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 36 17 48 0 ENST00000445355.3:c.821G>A p.Trp274Ter p.W274* ENST00000445355 NM_001109.4 274 tGg/tAg 0 +ADAMTS13 UCSF GRCh37 9 136320640 136320640 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 30 81 0 ENST00000371929.3:c.3483G>A p.Trp1161Ter p.W1161* ENST00000371929 NM_139025.4 1161 tgG/tgA 0 +ADAMTS13 UCSF GRCh37 9 136303014 136303014 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 36 95 0 ENST00000371929.3:c.1581C>T p.Cys527= p.C527= ENST00000371929 NM_139025.4 527 tgC/tgT 0 +ADAMTS13 UCSF GRCh37 9 136313814 136313814 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 24 62 0 ENST00000371929.3:c.2826G>A p.Arg942= p.R942= ENST00000371929 NM_139025.4 942 cgG/cgA 0 +ADAMTS15 UCSF GRCh37 11 130319744 130319744 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 50 121 0 ENST00000299164.2:c.876C>T p.Phe292= p.F292= ENST00000299164 NM_139055.2 292 ttC/ttT 0 +ADAMTS4 UCSF GRCh37 1 161166346 161166346 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 34 117 0 ENST00000367996.5:c.957+1G>A p.X319_splice ENST00000367996 NM_005099.4 0 +ADAMTS9 UCSF GRCh37 3 64607929 64607929 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 63 127 0 ENST00000498707.1:c.2631G>A p.Gln877= p.Q877= ENST00000498707 NM_182920.1 877 caG/caA 0 +ADAMTSL4 UCSF GRCh37 1 150531823 150531823 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 56 115 0 ENST00000271643.4:c.2824G>A p.Gly942Arg p.G942R ENST00000271643 NM_019032.4 942 Ggg/Agg 0 +ADCK5 UCSF GRCh37 8 145618060 145618060 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 12 0 ENST00000308860.6:c.1590C>T p.Arg530= p.R530= ENST00000308860 NM_174922.4 530 cgC/cgT 0 +ADCY10 UCSF GRCh37 1 167847697 167847697 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 110 92 176 0 ENST00000367851.4:c.1393C>G p.Arg465Gly p.R465G ENST00000367851 NM_018417.4 465 Cgt/Ggt 0 +ADCY9 UCSF GRCh37 16 4015884 4015884 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 185 72 200 0 ENST00000294016.3:c.3954C>T p.Ala1318= p.A1318= ENST00000294016 NM_001116.3 1318 gcC/gcT 0 +ADCY9 UCSF GRCh37 16 4163830 4163830 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 265 99 244 0 ENST00000294016.3:c.1614C>T p.Tyr538= p.Y538= ENST00000294016 NM_001116.3 538 taC/taT 0 +ADH5 UCSF GRCh37 4 100006287 100006287 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 171 130 246 0 ENST00000296412.8:c.93G>A p.Lys31= p.K31= ENST00000296412 NM_000671.3 31 aaG/aaA 0 +ADORA3 UCSF GRCh37 1 112042978 112042978 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 203 148 309 0 ENST00000241356.4:c.551C>T p.Thr184Ile p.T184I ENST00000241356 NM_000677.3 184 aCc/aTc 0 +ADRB3 UCSF GRCh37 8 37823551 37823551 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 15 0 ENST00000345060.3:c.437G>A p.Gly146Asp p.G146D ENST00000345060 NM_000025.2 146 gGc/gAc 0 +ADRBK2 UCSF GRCh37 22 26110537 26110537 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 51 99 0 ENST00000324198.6:c.1654G>A p.Asp552Asn p.D552N ENST00000324198 NM_005160.3 552 Gat/Aat 0 +ADSL UCSF GRCh37 22 40749101 40749101 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 74 56 116 0 ENST00000216194.7:c.382C>T p.Leu128Phe p.L128F ENST00000216194 NM_000026.2 128 Ctt/Ttt 0 +AFF2 UCSF GRCh37 X 148037697 148037697 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 123 104 0 ENST00000370460.2:c.2122C>T p.Arg708Trp p.R708W ENST00000370460 NM_002025.3 708 Cgg/Tgg 0 +AFF4 UCSF GRCh37 5 132238158 132238158 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 34 90 0 ENST00000265343.5:c.1109C>T p.Thr370Ile p.T370I ENST00000265343 NM_014423.3 370 aCt/aTt 0 +AGA UCSF GRCh37 4 178357482 178357482 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 51 142 0 ENST00000264595.2:c.646G>A p.Gly216Arg p.G216R ENST00000264595 NM_001171988.1 216 Gga/Aga 0 +AGAP1 UCSF GRCh37 2 237029007 237029007 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 46 121 0 ENST00000304032.8:c.2286G>A p.Glu762= p.E762= ENST00000304032 NM_001037131.2 762 gaG/gaA 0 +AGAP5 UCSF GRCh37 10 75434558 75434558 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 66 285 0 ENST00000374094.4:c.1860G>A p.Gly620= p.G620= ENST00000374094 NM_001144000.1 620 ggG/ggA 0 +AGBL1 UCSF GRCh37 15 86790901 86790901 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 34 16 76 0 ENST00000441037.2:c.389-1G>A p.X130_splice ENST00000441037 NM_152336.2 0 +AGBL3 UCSF GRCh37 7 134674001 134674001 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 34 63 0 ENST00000436302.2:c.64G>A p.Asp22Asn p.D22N ENST00000436302 NM_178563.3 22 Gat/Aat 0 +AGBL5 UCSF GRCh37 2 27282331 27282331 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 69 151 0 ENST00000360131.4:c.2089+59G>A *697* ENST00000360131 NM_021831.5 0 +AGRP UCSF GRCh37 16 67516602 67516602 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 73 64 112 0 ENST00000290953.2:c.336C>T p.Phe112= p.F112= ENST00000290953 NM_001138.1 112 ttC/ttT 0 +AHCY UCSF GRCh37 20 32880197 32880197 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 37 88 0 ENST00000217426.2:c.412C>T p.Leu138Phe p.L138F ENST00000217426 NM_000687.2 138 Ctc/Ttc 0 +AHI1 UCSF GRCh37 6 135732643 135732643 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 162 116 240 0 ENST00000265602.6:c.2804G>A p.Gly935Glu p.G935E ENST00000265602 NM_001134831.1 935 gGa/gAa 0 +AHI1 UCSF GRCh37 6 135787067 135787067 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 164 325 0 ENST00000265602.6:c.634C>T p.Leu212= p.L212= ENST00000265602 NM_001134831.1 212 Ctg/Ttg 0 +AHNAK UCSF GRCh37 11 62284334 62284334 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 121 254 0 ENST00000378024.4:c.17555G>A p.Gly5852Glu p.G5852E ENST00000378024 NM_001620.2 5852 gGg/gAg 0 +AHNAK UCSF GRCh37 11 62294198 62294198 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 205 180 305 0 ENST00000378024.4:c.7691G>A p.Gly2564Glu p.G2564E ENST00000378024 NM_001620.2 2564 gGg/gAg 0 +AIM2 UCSF GRCh37 1 159036085 159036085 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 70 197 0 ENST00000368130.4:c.431C>T p.Ser144Phe p.S144F ENST00000368130 NM_004833.1 144 tCt/tTt 0 +AKAP11 UCSF GRCh37 13 42874392 42874392 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 110 66 188 0 ENST00000025301.2:c.1510C>T p.Leu504Phe p.L504F ENST00000025301 NM_016248.3 504 Ctt/Ttt 0 +AKAP2 UCSF GRCh37 9 112899087 112899087 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 67 129 0 ENST00000259318.7:c.570C>T p.Pro190= p.P190= ENST00000259318 NM_001136562.2 190 ccC/ccT 0 +AKAP3 UCSF GRCh37 12 4736817 4736817 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 172 129 258 0 ENST00000228850.1:c.1251C>T p.Asn417= p.N417= ENST00000228850 417 aaC/aaT 0 +AKAP8L UCSF GRCh37 19 15512246 15512246 + synonymous_variant Silent SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 34 89 0 ENST00000397410.5:c.531T>A p.Gly177= p.G177= ENST00000397410 NM_014371.2 177 ggT/ggA 0 +AKR1C1 UCSF GRCh37 10 5008159 5008159 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 269 102 207 0 ENST00000380872.4:c.138C>T p.Phe46= p.F46= ENST00000380872 NM_001353.5 46 ttC/ttT 0 +AKR1E2 UCSF GRCh37 10 4872956 4872956 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 199 76 178 0 ENST00000298375.7:c.129G>A p.Glu43= p.E43= ENST00000298375 NM_001040177.2 43 gaG/gaA 0 +AKTIP UCSF GRCh37 16 53532381 53532381 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 117 278 0 ENST00000394657.7:c.170C>T p.Ala57Val p.A57V ENST00000394657 NM_022476.2 57 gCc/gTc 0 +ALDH1L1 UCSF GRCh37 3 125826076 125826076 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 77 172 0 ENST00000393434.2:c.2361G>A p.Glu787= p.E787= ENST00000393434 NM_012190.3 787 gaG/gaA 0 +ALDH3B1 UCSF GRCh37 11 67790074 67790074 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 41 70 0 ENST00000342456.6:c.847C>T p.Leu283= p.L283= ENST00000342456 NM_001030010.1 283 Ctg/Ttg 0 +ALDH3B2 UCSF GRCh37 11 67433865 67433865 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 13 17 0 ENST00000349015.3:c.159C>T p.Cys53= p.C53= ENST00000349015 NM_000695.3 53 tgC/tgT 0 +ALDH6A1 UCSF GRCh37 14 74533452 74533452 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 91 201 0 ENST00000553458.1:c.1180G>A p.Glu394Lys p.E394K ENST00000553458 NM_001278593.1 394 Gaa/Aaa 0 +ALG9 UCSF GRCh37 11 111708288 111708288 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 58 146 0 ENST00000531154.1:c.862G>A p.Asp288Asn p.D288N ENST00000531154 NM_024740.2 288 Gac/Aac 0 +ALKBH5 UCSF GRCh37 17 18110225 18110225 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 196 125 261 0 ENST00000399138.4:c.948G>A p.Arg316= p.R316= ENST00000399138 NM_017758.3 316 agG/agA 0 +ALMS1 UCSF GRCh37 2 73678109 73678109 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 165 137 267 0 ENST00000264448.6:c.4452C>T p.Ile1484= p.I1484= ENST00000264448 NM_015120.4 1484 atC/atT 0 +ALOX12B UCSF GRCh37 17 7977054 7977054 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 24 64 0 ENST00000319144.4:c.1676C>T p.Thr559Ile p.T559I ENST00000319144 NM_001139.2 559 aCc/aTc 0 +ALPL UCSF GRCh37 1 21890579 21890579 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 30 72 0 ENST00000374832.1:c.518C>T p.Thr173Ile p.T173I ENST00000374832 173 aCc/aTc 0 +ALPPL2 UCSF GRCh37 2 233274457 233274457 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 17 22 0 ENST00000295453.3:c.1474G>A p.Ala492Thr p.A492T ENST00000295453 NM_031313.2 492 Gcc/Acc 0 +ALS2CL UCSF GRCh37 3 46729143 46729143 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 22 46 0 ENST00000318962.4:c.334G>A p.Val112Met p.V112M ENST00000318962 NM_147129.3 112 Gtg/Atg 0 +ALS2CL UCSF GRCh37 3 46713075 46713075 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 39 88 0 ENST00000318962.4:c.2685-1G>A p.X895_splice ENST00000318962 NM_147129.3 0 +AMBRA1 UCSF GRCh37 11 46430176 46430176 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 38 73 0 ENST00000458649.2:c.3290C>T p.Thr1097Ile p.T1097I ENST00000458649 1097 aCc/aTc 0 +AMPD2 UCSF GRCh37 1 110173373 110173373 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 20 0 ENST00000256578.3:c.2388G>A p.Glu796= p.E796= ENST00000256578 NM_004037.7 796 gaG/gaA 0 +AMPH UCSF GRCh37 7 38534069 38534069 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 97 183 0 ENST00000356264.2:c.264C>T p.Asp88= p.D88= ENST00000356264 NM_001635.3 88 gaC/gaT 0 +AMT UCSF GRCh37 3 49455068 49455068 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 85 169 0 ENST00000273588.3:c.1117G>A p.Gly373Arg p.G373R ENST00000273588 NM_000481.3 373 Ggg/Agg 0 +AMY2A UCSF GRCh37 1 104160104 104160104 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 412 106 634 0 ENST00000414303.2:c.42G>A p.Trp14Ter p.W14* ENST00000414303 NM_000699.2 14 tgG/tgA 0 +ANK2 UCSF GRCh37 4 114276282 114276282 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 79 154 0 ENST00000357077.4:c.6508C>T p.Leu2170Phe p.L2170F ENST00000357077 NM_001148.4 2170 Ctc/Ttc 0 +ANK3 UCSF GRCh37 10 61898737 61898737 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 135 103 184 0 ENST00000280772.2:c.2723G>A p.Gly908Glu p.G908E ENST00000280772 NM_020987.3 908 gGa/gAa 0 +ANK3 UCSF GRCh37 10 61835701 61835701 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 66 154 0 ENST00000280772.2:c.4938C>T p.Ser1646= p.S1646= ENST00000280772 NM_020987.3 1646 tcC/tcT 0 +ANKDD1A UCSF GRCh37 15 65208096 65208096 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 30 63 0 ENST00000319580.8:c.34+3933C>T *12* ENST00000319580 0 +ANKRA2 UCSF GRCh37 5 72858513 72858513 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 184 147 257 0 ENST00000296785.3:c.194G>A p.Cys65Tyr p.C65Y ENST00000296785 NM_023039.4 65 tGt/tAt 0 +ANKRD11 UCSF GRCh37 16 89371633 89371633 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 35 64 0 ENST00000301030.4:c.207G>A p.Glu69= p.E69= ENST00000301030 NM_001256183.1 69 gaG/gaA 0 +ANKRD13B UCSF GRCh37 17 27939242 27939242 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 66 165 0 ENST00000394859.3:c.1209C>T p.Leu403= p.L403= ENST00000394859 NM_152345.4 403 ctC/ctT 0 +ANKRD13C UCSF GRCh37 1 70819858 70819858 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 60 134 0 ENST00000370944.4:c.234G>A p.Leu78= p.L78= ENST00000370944 NM_030816.4 78 ctG/ctA 0 +ANKRD13C UCSF GRCh37 1 70736609 70736609 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 34 102 0 ENST00000370944.4:c.1425C>T p.Pro475= p.P475= ENST00000370944 NM_030816.4 475 ccC/ccT 0 +ANKRD17 UCSF GRCh37 4 73957296 73957296 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 202 148 352 0 ENST00000358602.4:c.6049G>A p.Ala2017Thr p.A2017T ENST00000358602 NM_032217.3 2017 Gca/Aca 0 +ANKRD17 UCSF GRCh37 4 74017241 74017241 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 41 127 0 ENST00000358602.4:c.1235G>A p.Gly412Glu p.G412E ENST00000358602 NM_032217.3 412 gGa/gAa 0 +ANKRD2 UCSF GRCh37 10 99342361 99342361 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 66 168 0 ENST00000307518.5:c.835G>A p.Glu279Lys p.E279K ENST00000307518 279 Gaa/Aaa 0 +ANKRD20A4 UCSF GRCh37 9 69423583 69423583 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 444 83 953 0 ENST00000357336.3:c.1879G>A p.Glu627Lys p.E627K ENST00000357336 NM_001098805.1 627 Gaa/Aaa 0 +ANKRD36 UCSF GRCh37 2 97909671 97909671 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 156 93 300 0 ENST00000420699.2:c.4474C>T p.Gln1492Ter p.Q1492* ENST00000420699 NM_001164315.1 1492 Caa/Taa 0 +ANKRD57 UCSF GRCh37 2 110373562 110373562 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 49 108 0 ENST00000356454.3:c.1496G>A p.Gly499Glu p.G499E ENST00000356454 NM_023016.3 499 gGg/gAg 0 +ANKZF1 UCSF GRCh37 2 220095054 220095054 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 40 72 0 ENST00000323348.5:c.75C>T p.Val25= p.V25= ENST00000323348 NM_018089.2 25 gtC/gtT 0 +ANO10 UCSF GRCh37 3 43602826 43602826 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 80 213 0 ENST00000292246.3:c.1362G>A p.Trp454Ter p.W454* ENST00000292246 NM_018075.3 454 tgG/tgA 0 +ANO3 UCSF GRCh37 11 26484612 26484612 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 69 155 0 ENST00000256737.3:c.349G>A p.Glu117Lys p.E117K ENST00000256737 NM_031418.2 117 Gaa/Aaa 0 +ANO3 UCSF GRCh37 11 26664788 26664788 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 89 189 0 ENST00000256737.3:c.2335G>A p.Ala779Thr p.A779T ENST00000256737 NM_031418.2 779 Gct/Act 0 +ANXA7 UCSF GRCh37 10 75158082 75158082 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 34 79 0 ENST00000372919.4:c.116C>T p.Pro39Leu p.P39L ENST00000372919 NM_004034.2 39 cCt/cTt 0 +AOC3 UCSF GRCh37 17 41006484 41006484 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 44 33 74 0 ENST00000308423.2:c.1620G>A p.Trp540Ter p.W540* ENST00000308423 NM_003734.3 540 tgG/tgA 0 +AP1M1 UCSF GRCh37 19 16339647 16339647 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 41 86 0 ENST00000291439.3:c.955G>A p.Asp319Asn p.D319N ENST00000291439 NM_032493.3 319 Gat/Aat 0 +AP3D1 UCSF GRCh37 19 2114812 2114812 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 40 108 0 ENST00000345016.5:c.2358G>A p.Leu786= p.L786= ENST00000345016 NM_003938.6 786 ctG/ctA 0 +AP3M2 UCSF GRCh37 8 42025183 42025183 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 91 224 0 ENST00000174653.3:c.1012-1G>A p.X338_splice ENST00000174653 NM_006803.3 0 +APBB1IP UCSF GRCh37 10 26856330 26856330 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 17 52 0 ENST00000376236.4:c.1914G>A p.Gly638= p.G638= ENST00000376236 NM_019043.3 638 ggG/ggA 0 +APBB3 UCSF GRCh37 5 139942017 139942017 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 119 256 0 ENST00000357560.4:c.419G>A p.Ser140Asn p.S140N ENST00000357560 NM_133173.2 140 aGt/aAt 0 +APC UCSF GRCh37 5 112177881 112177881 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 76 219 0 ENST00000257430.4:c.6590G>A p.Ser2197Asn p.S2197N ENST00000257430 NM_000038.5 2197 aGt/aAt 0 +APLP1 UCSF GRCh37 19 36362177 36362177 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 13 28 0 ENST00000221891.4:c.463G>A p.Gly155Ser p.G155S ENST00000221891 NM_001024807.1 155 Ggc/Agc 0 +APOA4 UCSF GRCh37 11 116692033 116692033 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 72 170 0 ENST00000357780.3:c.741G>A p.Lys247= p.K247= ENST00000357780 NM_000482.3 247 aaG/aaA 0 +APPBP2 UCSF GRCh37 17 58571898 58571898 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 128 93 180 0 ENST00000083182.3:c.308G>A p.Arg103Lys p.R103K ENST00000083182 NM_006380.2 103 aGg/aAg 0 +AQP12B UCSF GRCh37 2 241621893 241621893 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 25 61 0 ENST00000407834.3:c.362G>A p.Gly121Asp p.G121D ENST00000407834 NM_001102467.1 121 gGc/gAc 0 +AQPEP UCSF GRCh37 5 115298720 115298720 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 36 68 0 ENST00000357872.4:c.406C>T p.Arg136Cys p.R136C ENST00000357872 NM_173800.4 136 Cgc/Tgc 0 +ARAP2 UCSF GRCh37 4 36212219 36212219 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 160 104 270 0 ENST00000303965.4:c.1280G>A p.Arg427Lys p.R427K ENST00000303965 NM_015230.3 427 aGa/aAa 0 +ARAP2 UCSF GRCh37 4 36149369 36149369 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 30 65 0 ENST00000303965.4:c.3001-1G>A p.X1001_splice ENST00000303965 NM_015230.3 0 +ARFGEF2 UCSF GRCh37 20 47601368 47601368 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 134 88 187 0 ENST00000371917.4:c.2061C>T p.Arg687= p.R687= ENST00000371917 NM_006420.2 687 cgC/cgT 0 +ARG1 UCSF GRCh37 6 131904993 131904993 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 76 159 0 ENST00000368087.3:c.914G>A p.Gly305Glu p.G305E ENST00000368087 305 gGa/gAa 0 +ARHGAP12 UCSF GRCh37 10 32120720 32120720 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 199 66 116 1 ENST00000344936.2:c.1395G>A p.Glu465= p.E465= ENST00000344936 NM_001270697.1 465 gaG/gaA 0 +ARHGAP17 UCSF GRCh37 16 24946897 24946897 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 31 59 0 ENST00000289968.6:c.1788G>A p.Gln596= p.Q596= ENST00000289968 NM_001006634.1 596 caG/caA 0 +ARHGAP21 UCSF GRCh37 10 24885691 24885691 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 211 74 166 0 ENST00000396432.2:c.3455G>A p.Cys1152Tyr p.C1152Y ENST00000396432 NM_020824.3 1152 tGc/tAc 0 +ARHGAP21 UCSF GRCh37 10 24922386 24922386 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 47 115 0 ENST00000396432.2:c.385G>A p.Gly129Arg p.G129R ENST00000396432 NM_020824.3 129 Gga/Aga 0 +ARHGAP24 UCSF GRCh37 4 86915904 86915904 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 183 158 302 0 ENST00000395184.1:c.1097C>T p.Thr366Ile p.T366I ENST00000395184 NM_001025616.2 366 aCc/aTc 0 +ARHGAP29 UCSF GRCh37 1 94643491 94643491 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 100 189 0 ENST00000260526.6:c.2713G>A p.Gly905Ser p.G905S ENST00000260526 NM_004815.3 905 Ggc/Agc 0 +ARHGAP29 UCSF GRCh37 1 94650550 94650550 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 32 79 0 ENST00000260526.6:c.1987C>T p.Pro663Ser p.P663S ENST00000260526 NM_004815.3 663 Cca/Tca 0 +ARHGAP29 UCSF GRCh37 1 94655595 94655595 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 55 109 0 ENST00000260526.6:c.1326C>T p.Ser442= p.S442= ENST00000260526 NM_004815.3 442 tcC/tcT 0 +ARHGAP35 UCSF GRCh37 19 47422027 47422027 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 175 149 251 0 ENST00000404338.3:c.95G>A p.Gly32Glu p.G32E ENST00000404338 NM_004491.4 32 gGg/gAg 0 +ARHGAP35 UCSF GRCh37 19 47423996 47423996 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 87 184 0 ENST00000404338.3:c.2064G>A p.Arg688= p.R688= ENST00000404338 NM_004491.4 688 cgG/cgA 0 +ARHGAP39 UCSF GRCh37 8 145759561 145759561 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 35 111 0 ENST00000276826.5:c.2547G>A p.Lys849= p.K849= ENST00000276826 849 aaG/aaA 0 +ARHGAP9 UCSF GRCh37 12 57869182 57869182 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 3 11 19 0 ENST00000393791.3:c.1445-1G>A p.X482_splice ENST00000393791 NM_032496.2 0 +ARHGAP9 UCSF GRCh37 12 57872322 57872322 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 75 137 0 ENST00000393791.3:c.534+1G>A p.X178_splice ENST00000393791 NM_032496.2 0 +ARHGEF17 UCSF GRCh37 11 73022664 73022664 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 65 129 0 ENST00000263674.3:c.2981C>T p.Ala994Val p.A994V ENST00000263674 NM_014786.3 994 gCc/gTc 0 +ARHGEF17 UCSF GRCh37 11 73076881 73076881 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 40 104 0 ENST00000263674.3:c.5884C>T p.Pro1962Ser p.P1962S ENST00000263674 NM_014786.3 1962 Ccc/Tcc 0 +ARID1A UCSF GRCh37 1 27101587 27101587 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 88 173 0 ENST00000324856.7:c.4869G>A p.Ser1623= p.S1623= ENST00000324856 NM_006015.4 1623 tcG/tcA 0 +ARL4D UCSF GRCh37 17 41477501 41477501 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 15 46 0 ENST00000320033.4:c.401C>T p.Ala134Val p.A134V ENST00000320033 NM_001661.3 134 gCc/gTc 0 +ARMC8 UCSF GRCh37 3 137956329 137956329 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 59 147 0 ENST00000469044.1:c.691G>A p.Val231Ile p.V231I ENST00000469044 NM_001267041.1 231 Gtt/Att 0 +ARNTL2 UCSF GRCh37 12 27554297 27554297 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 80 171 0 ENST00000266503.5:c.1267+1G>A p.X423_splice ENST00000266503 0 +ARSI UCSF GRCh37 5 149678062 149678062 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 47 70 0 ENST00000328668.7:c.425C>T p.Thr142Ile p.T142I ENST00000328668 NM_001012301.2 142 aCc/aTc 0 +ASB14 UCSF GRCh37 3 57322030 57322030 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P18_Rec Untested WXS Illumina HiSeq 6 0 ENST00000389601.3:c.371del p.Leu124TrpfsTer8 p.L124Wfs*8 ENST00000389601 NM_130387.5 124 tTg/tg 0 +ASB14 UCSF GRCh37 3 57317424 57317424 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 64 141 0 ENST00000389601.3:c.516C>T p.Asn172= p.N172= ENST00000389601 NM_130387.5 172 aaC/aaT 0 +ASCL4 UCSF GRCh37 12 108169329 108169329 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 8 17 0 ENST00000342331.4:c.337G>A p.Glu113Lys p.E113K ENST00000342331 NM_203436.2 113 Gag/Aag 0 +ASH1L UCSF GRCh37 1 155449560 155449560 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 109 198 0 ENST00000368346.3:c.3101G>A p.Gly1034Asp p.G1034D ENST00000368346 1034 gGc/gAc 0 +ASH1L UCSF GRCh37 1 155451426 155451426 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 89 220 0 ENST00000368346.3:c.1235C>T p.Pro412Leu p.P412L ENST00000368346 412 cCt/cTt 0 +ASTN2 UCSF GRCh37 9 119568068 119568068 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 113 266 0 ENST00000313400.4:c.2239G>A p.Gly747Arg p.G747R ENST00000313400 747 Gga/Aga 0 +ASTN2 UCSF GRCh37 9 120053656 120053656 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 37 88 0 ENST00000313400.4:c.579G>A p.Glu193= p.E193= ENST00000313400 193 gaG/gaA 0 +ASXL3 UCSF GRCh37 18 31326351 31326351 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 151 108 207 0 ENST00000269197.5:c.6539G>A p.Ser2180Asn p.S2180N ENST00000269197 NM_030632.1 2180 aGt/aAt 0 +ATAD3A UCSF GRCh37 1 1464667 1464667 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 15 40 0 ENST00000378755.5:c.1714G>A p.Gly572Ser p.G572S ENST00000378755 NM_018188.3 572 Ggc/Agc 0 +ATF7IP UCSF GRCh37 12 14631306 14631306 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 125 271 0 ENST00000261168.4:c.2997G>A p.Val999= p.V999= ENST00000261168 NM_018179.3 999 gtG/gtA 0 +ATG14 UCSF GRCh37 14 55836494 55836494 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 102 62 154 0 ENST00000247178.5:c.1322C>T p.Pro441Leu p.P441L ENST00000247178 NM_014924.4 441 cCc/cTc 0 +ATG2B UCSF GRCh37 14 96772039 96772039 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 65 127 0 ENST00000359933.4:c.4620C>T p.His1540= p.H1540= ENST00000359933 NM_018036.5 1540 caC/caT 0 +ATG3 UCSF GRCh37 3 112280342 112280342 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 16 60 0 ENST00000283290.5:c.34G>A p.Ala12Thr p.A12T ENST00000283290 NM_022488.4 12 Gca/Aca 0 +ATG9B UCSF GRCh37 7 150720273 150720273 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 172 116 229 0 ENST00000377974.2:c.680C>T p.Thr227Ile p.T227I ENST00000377974 227 aCc/aTc 0 +ATIC UCSF GRCh37 2 216177284 216177284 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 91 211 0 ENST00000236959.9:c.83G>A p.Gly28Asp p.G28D ENST00000236959 NM_004044.6 28 gGt/gAt 0 +ATM UCSF GRCh37 11 108183179 108183179 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 94 231 0 ENST00000278616.4:c.5960C>T p.Ser1987Phe p.S1987F ENST00000278616 NM_000051.3 1987 tCt/tTt 0 +ATP10D UCSF GRCh37 4 47537949 47537949 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 93 156 0 ENST00000273859.3:c.914G>A p.Ser305Asn p.S305N ENST00000273859 NM_020453.3 305 aGt/aAt 0 +ATP11B UCSF GRCh37 3 182554943 182554943 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 61 138 0 ENST00000323116.5:c.637C>T p.Pro213Ser p.P213S ENST00000323116 NM_014616.2 213 Cca/Tca 0 +ATP13A1 UCSF GRCh37 19 19767531 19767531 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 46 123 0 ENST00000357324.6:c.1021C>T p.Leu341= p.L341= ENST00000357324 NM_020410.2 341 Ctg/Ttg 0 +ATP13A5 UCSF GRCh37 3 193007755 193007755 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 65 132 0 ENST00000342358.4:c.2942C>T p.Ser981Phe p.S981F ENST00000342358 NM_198505.2 981 tCc/tTc 0 +ATP13A5 UCSF GRCh37 3 193032873 193032873 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 135 87 238 0 ENST00000342358.4:c.2046G>A p.Glu682= p.E682= ENST00000342358 NM_198505.2 682 gaG/gaA 0 +ATP1A2 UCSF GRCh37 1 160099137 160099137 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 137 236 0 ENST00000361216.3:c.1408G>A p.Asp470Asn p.D470N ENST00000361216 NM_000702.3 470 Gac/Aac 0 +ATP1A4 UCSF GRCh37 1 160136808 160136808 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 60 127 0 ENST00000368081.4:c.1297G>A p.Ala433Thr p.A433T ENST00000368081 NM_144699.3 433 Gct/Act 0 +ATP2A1 UCSF GRCh37 16 28893772 28893772 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 146 42 103 0 ENST00000357084.3:c.325G>A p.Glu109Lys p.E109K ENST00000357084 NM_173201.3 109 Gag/Aag 0 +ATP2B1 UCSF GRCh37 12 89992395 89992395 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 215 142 282 0 ENST00000428670.3:c.3351+499C>T *1117* ENST00000428670 0 +ATP2B2 UCSF GRCh37 3 10401790 10401790 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 23 74 0 ENST00000352432.4:c.1677C>T p.Gly559= p.G559= ENST00000352432 559 ggC/ggT 0 +ATP2B4 UCSF GRCh37 1 203676351 203676351 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 44 114 0 ENST00000357681.5:c.1314G>A p.Lys438= p.K438= ENST00000357681 NM_001684.4 438 aaG/aaA 0 +ATP4A UCSF GRCh37 19 36051518 36051518 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 22 40 0 ENST00000262623.3:c.535-1G>A p.X179_splice ENST00000262623 NM_000704.2 0 +ATP5B UCSF GRCh37 12 57036564 57036564 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 80 166 0 ENST00000262030.3:c.844G>A p.Val282Ile p.V282I ENST00000262030 NM_001686.3 282 Gta/Ata 0 +ATP5D UCSF GRCh37 19 1244102 1244102 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 10 16 0 ENST00000215375.2:c.302G>A p.Ser101Asn p.S101N ENST00000215375 NM_001687.4 101 aGc/aAc 0 +ATP6V1B1 UCSF GRCh37 2 71191996 71191996 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 55 91 0 ENST00000234396.4:c.1378+1G>A p.X460_splice ENST00000234396 NM_001692.3 0 +ATP7B UCSF GRCh37 13 52511448 52511448 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 62 138 0 ENST00000242839.4:c.3985C>T p.Leu1329= p.L1329= ENST00000242839 NM_000053.3 1329 Ctg/Ttg 0 +ATP8B2 UCSF GRCh37 1 154310054 154310054 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 111 219 0 ENST00000368489.3:c.1133+34G>A *378* ENST00000368489 NM_020452.3 0 +ATP8B4 UCSF GRCh37 15 50190448 50190448 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 53 100 0 ENST00000284509.6:c.2290G>A p.Ala764Thr p.A764T ENST00000284509 NM_024837.3 764 Gct/Act 0 +ATPIF1 UCSF GRCh37 1 28562889 28562889 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 62 143 0 ENST00000335514.5:c.105G>A p.Arg35= p.R35= ENST00000335514 NM_016311.4 35 cgG/cgA 0 +ATRN UCSF GRCh37 20 3624900 3624900 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 93 176 0 ENST00000262919.5:c.4150C>T p.Pro1384Ser p.P1384S ENST00000262919 NM_139321.2 1384 Cct/Tct 0 +ATRN UCSF GRCh37 20 3624889 3624889 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 77 162 0 ENST00000262919.5:c.4139G>A p.Gly1380Asp p.G1380D ENST00000262919 NM_139321.2 1380 gGt/gAt 0 +ATRN UCSF GRCh37 20 3556596 3556596 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 60 138 0 ENST00000262919.5:c.2214+1G>A p.X738_splice ENST00000262919 NM_139321.2 0 +ATRN UCSF GRCh37 20 3575208 3575208 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 36 23 78 0 ENST00000262919.5:c.3405C>T p.Asp1135= p.D1135= ENST00000262919 NM_139321.2 1135 gaC/gaT 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 62 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +ATXN1 UCSF GRCh37 6 16326873 16326873 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 49 117 1 ENST00000244769.4:c.1669G>A p.Val557Met p.V557M ENST00000244769 NM_000332.3 557 Gtg/Atg 0 +ATXN7L1 UCSF GRCh37 7 105254967 105254967 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 85 165 0 ENST00000419735.3:c.1814C>T p.Ser605Phe p.S605F ENST00000419735 NM_020725.1 605 tCc/tTc 0 +AURKC UCSF GRCh37 19 57744827 57744827 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 65 150 0 ENST00000302804.7:c.436-1G>A p.X146_splice ENST00000302804 NM_001015878.1 0 +AUTS2 UCSF GRCh37 7 69755436 69755436 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 111 208 0 ENST00000342771.4:c.661-145302C>T *221* ENST00000342771 NM_015570.2 0 +AVP UCSF GRCh37 20 3065294 3065294 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 80 129 0 ENST00000380293.3:c.27C>T p.Cys9= p.C9= ENST00000380293 NM_000490.4 9 tgC/tgT 0 +AVPI1 UCSF GRCh37 10 99439523 99439523 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 16 66 0 ENST00000370626.3:c.140G>A p.Gly47Glu p.G47E ENST00000370626 NM_021732.2 47 gGg/gAg 0 +AVPR1B UCSF GRCh37 1 206224614 206224614 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 48 133 0 ENST00000367126.4:c.174C>T p.Thr58= p.T58= ENST00000367126 NM_000707.3 58 acC/acT 0 +AXIN2 UCSF GRCh37 17 63554369 63554369 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 183 128 254 0 ENST00000307078.5:c.370G>A p.Asp124Asn p.D124N ENST00000307078 NM_004655.3 124 Gat/Aat 0 +AXIN2 UCSF GRCh37 17 63526149 63526149 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 91 195 0 ENST00000307078.5:c.2477C>T p.Thr826Met p.T826M ENST00000307078 NM_004655.3 826 aCg/aTg 0 +AZI2 UCSF GRCh37 3 28378370 28378370 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 76 186 0 ENST00000479665.1:c.446G>A p.Arg149Lys p.R149K ENST00000479665 NM_022461.4 149 aGg/aAg 0 +B3GALT5 UCSF GRCh37 21 41033171 41033171 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 82 214 0 ENST00000343118.4:c.685G>A p.Val229Met p.V229M ENST00000343118 NM_033171.2 229 Gtg/Atg 0 +B3GNT7 UCSF GRCh37 2 232262835 232262835 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 41 93 0 ENST00000287590.5:c.405C>T p.Tyr135= p.Y135= ENST00000287590 NM_145236.2 135 taC/taT 0 +B4GALNT2 UCSF GRCh37 17 47210398 47210398 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 24 37 0 ENST00000300404.2:c.11C>T p.Ala4Val p.A4V ENST00000300404 NM_153446.2 4 gCt/gTt 0 +B4GALNT2 UCSF GRCh37 17 47246984 47246984 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 58 142 0 ENST00000300404.2:c.1595C>T p.Ala532Val p.A532V ENST00000300404 NM_153446.2 532 gCt/gTt 0 +B4GALNT2 UCSF GRCh37 17 47247083 47247083 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 47 41 99 0 ENST00000300404.2:c.1694C>T p.Ala565Val p.A565V ENST00000300404 NM_153446.2 565 gCc/gTc 0 +B4GALT5 UCSF GRCh37 20 48257080 48257080 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 82 198 1 ENST00000371711.4:c.729C>T p.Arg243= p.R243= ENST00000371711 NM_004776.3 243 cgC/cgT 0 +BACH1 UCSF GRCh37 21 30714969 30714969 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 61 183 0 ENST00000286800.3:c.2026C>T p.Pro676Ser p.P676S ENST00000286800 NM_001186.2 676 Cct/Tct 0 +BACH2 UCSF GRCh37 6 90718495 90718495 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 67 145 0 ENST00000257749.4:c.69C>T p.Ile23= p.I23= ENST00000257749 NM_021813.2 23 atC/atT 0 +BAG2 UCSF GRCh37 6 57048790 57048790 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 76 183 0 ENST00000370693.5:c.438G>A p.Val146= p.V146= ENST00000370693 NM_004282.3 146 gtG/gtA 0 +BAIAP3 UCSF GRCh37 16 1397301 1397301 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 36 9 31 0 ENST00000324385.5:c.2859C>T p.Ala953= p.A953= ENST00000324385 NM_003933.4 953 gcC/gcT 0 +BANK1 UCSF GRCh37 4 102984291 102984291 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 33 108 0 ENST00000322953.4:c.2208C>T p.Val736= p.V736= ENST00000322953 NM_017935.4 736 gtC/gtT 0 +BAZ2B UCSF GRCh37 2 160269006 160269006 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 51 101 0 ENST00000392783.2:c.2517G>A p.Arg839= p.R839= ENST00000392783 NM_013450.2 839 agG/agA 0 +BBS7 UCSF GRCh37 4 122768661 122768661 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 91 181 0 ENST00000264499.4:c.935G>A p.Gly312Asp p.G312D ENST00000264499 NM_176824.2 312 gGc/gAc 0 +BBX UCSF GRCh37 3 107497265 107497265 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 84 194 0 ENST00000325805.8:c.2102C>T p.Pro701Leu p.P701L ENST00000325805 701 cCt/cTt 0 +BCAR3 UCSF GRCh37 1 94032835 94032835 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 64 119 0 ENST00000260502.6:c.2299+1G>A p.X767_splice ENST00000260502 NM_003567.3 0 +BCAT2 UCSF GRCh37 19 49300543 49300543 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 23 40 0 ENST00000316273.6:c.743G>A p.Gly248Asp p.G248D ENST00000316273 NM_001190.3 248 gGc/gAc 0 +BCL11A UCSF GRCh37 2 60688867 60688867 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 73 113 0 ENST00000335712.6:c.1180G>A p.Val394Met p.V394M ENST00000335712 NM_022893.3 394 Gtg/Atg 0 +BCL11B UCSF GRCh37 14 99723979 99723979 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 67 129 0 ENST00000357195.3:c.256G>A p.Gly86Ser p.G86S ENST00000357195 NM_138576.2 86 Ggt/Agt 0 +BCL11B UCSF GRCh37 14 99724090 99724090 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 58 107 0 ENST00000357195.3:c.145G>A p.Gly49Ser p.G49S ENST00000357195 NM_138576.2 49 Ggt/Agt 0 +BCL9L UCSF GRCh37 11 118770897 118770897 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 10 47 0 ENST00000334801.3:c.3135G>A p.Pro1045= p.P1045= ENST00000334801 NM_182557.2 1045 ccG/ccA 0 +BCLAF1 UCSF GRCh37 6 136597646 136597646 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 110 83 246 0 ENST00000531224.1:c.1017G>A p.Arg339= p.R339= ENST00000531224 NM_001077441.1 339 agG/agA 0 +BCORL1 UCSF GRCh37 X 129148508 129148508 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 7 50 77 0 ENST00000218147.7:c.1760C>T p.Thr587Ile p.T587I ENST00000218147 587 aCc/aTc 0 +BDP1 UCSF GRCh37 5 70819776 70819776 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 72 176 0 ENST00000358731.4:c.5398C>T p.Pro1800Ser p.P1800S ENST00000358731 NM_018429.2 1800 Ccg/Tcg 0 +BEX2 UCSF GRCh37 X 102564611 102564611 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 152 153 0 ENST00000372674.1:c.294G>A p.Lys98= p.K98= ENST00000372674 NM_001168401.1 98 aaG/aaA 0 +BHLHE40 UCSF GRCh37 3 5024966 5024966 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 317 75 178 0 ENST00000256495.3:c.828C>T p.Gly276= p.G276= ENST00000256495 NM_003670.2 276 ggC/ggT 0 +BIN1 UCSF GRCh37 2 127808783 127808783 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 20 33 0 ENST00000316724.5:c.1408C>T p.Pro470Ser p.P470S ENST00000316724 NM_139343.2 470 Cct/Tct 0 +BLM UCSF GRCh37 15 91328173 91328173 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 139 252 0 ENST00000355112.3:c.2685C>T p.Cys895= p.C895= ENST00000355112 NM_000057.2 895 tgC/tgT 0 +BMP4 UCSF GRCh37 14 54417031 54417031 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 50 109 0 ENST00000245451.4:c.946G>A p.Asp316Asn p.D316N ENST00000245451 NM_001202.3 316 Gac/Aac 0 +BOD1L UCSF GRCh37 4 13603033 13603033 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 222 159 354 0 ENST00000040738.5:c.5491G>A p.Asp1831Asn p.D1831N ENST00000040738 NM_148894.2 1831 Gac/Aac 0 +BOD1L UCSF GRCh37 4 13616011 13616011 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 80 212 0 ENST00000040738.5:c.983G>A p.Ser328Asn p.S328N ENST00000040738 NM_148894.2 328 aGc/aAc 0 +BPHL UCSF GRCh37 6 3140744 3140744 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 166 88 214 0 ENST00000380379.5:c.788+1G>A p.X263_splice ENST00000380379 NM_004332.2 0 +BPIFB1 UCSF GRCh37 20 31897518 31897518 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 74 54 138 1 ENST00000253354.1:c.1400C>T p.Ala467Val p.A467V ENST00000253354 NM_033197.2 467 gCc/gTc 0 +BPIFB3 UCSF GRCh37 20 31644420 31644420 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 77 180 0 ENST00000375494.3:c.197G>A p.Gly66Asp p.G66D ENST00000375494 NM_182658.1 66 gGc/gAc 0 +BPTF UCSF GRCh37 17 65955886 65955886 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 61 112 0 ENST00000321892.4:c.8534C>T p.Ser2845Phe p.S2845F ENST00000321892 2845 tCc/tTc 0 +BRCA1 UCSF GRCh37 17 41215370 41215370 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 45 125 0 ENST00000357654.3:c.5173G>A p.Glu1725Lys p.E1725K ENST00000357654 NM_007294.3 1725 Gaa/Aaa 0 +BRCA2 UCSF GRCh37 13 32910602 32910602 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 61 148 0 ENST00000380152.3:c.2110C>T p.Pro704Ser p.P704S ENST00000380152 704 Cca/Tca 0 +BRCA2 UCSF GRCh37 13 32930720 32930720 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 85 262 0 ENST00000380152.3:c.7591G>A p.Val2531Ile p.V2531I ENST00000380152 2531 Gtt/Att 0 +BRD1 UCSF GRCh37 22 50187939 50187939 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 43 93 0 ENST00000216267.8:c.2102A>T p.Asp701Val p.D701V ENST00000216267 NM_014577.1 701 gAc/gTc 0 +BRD2 UCSF GRCh37 6 32944590 32944590 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 160 132 238 0 ENST00000374825.4:c.1077G>A p.Glu359= p.E359= ENST00000374825 NM_005104.3 359 gaG/gaA 0 +BRF1 UCSF GRCh37 14 105685573 105685573 + splice_region_variant,intron_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 51 126 0 ENST00000546474.1:c.1378-4C>T p.X460_splice ENST00000546474 NM_001519.3 0 +BRI3 UCSF GRCh37 7 97920429 97920429 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 48 118 0 ENST00000297290.3:c.252G>A p.Gly84= p.G84= ENST00000297290 NM_015379.4 84 ggG/ggA 0 +BRPF1 UCSF GRCh37 3 9775866 9775866 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 60 131 0 ENST00000457855.1:c.42G>A p.Leu14= p.L14= ENST00000457855 14 ttG/ttA 0 +BRPF3 UCSF GRCh37 6 36178173 36178173 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 78 146 0 ENST00000357641.6:c.2047C>T p.Arg683Trp p.R683W ENST00000357641 NM_015695.2 683 Cgg/Tgg 0 +BRPF3 UCSF GRCh37 6 36185780 36185780 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 62 121 0 ENST00000357641.6:c.3076G>A p.Ala1026Thr p.A1026T ENST00000357641 NM_015695.2 1026 Gct/Act 0 +BSND UCSF GRCh37 1 55473906 55473906 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 23 78 0 ENST00000371265.4:c.568G>A p.Gly190Ser p.G190S ENST00000371265 NM_057176.2 190 Ggc/Agc 0 +BTBD9 UCSF GRCh37 6 38545422 38545422 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 74 182 0 ENST00000481247.1:c.1108C>T p.Leu370= p.L370= ENST00000481247 NM_052893.1 370 Ctg/Ttg 0 +BTD UCSF GRCh37 3 15686403 15686403 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 99 209 0 ENST00000303498.5:c.1040C>T p.Ala347Val p.A347V ENST00000303498 NM_000060.2 347 gCa/gTa 0 +BTN2A2 UCSF GRCh37 6 26385433 26385433 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 62 162 0 ENST00000356709.4:c.285G>A p.Glu95= p.E95= ENST00000356709 NM_001197240.1 95 gaG/gaA 0 +BUD13 UCSF GRCh37 11 116633778 116633778 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 96 257 0 ENST00000260210.4:c.527C>T p.Pro176Leu p.P176L ENST00000260210 NM_032725.3 176 cCt/cTt 0 +BZRAP1 UCSF GRCh37 17 56382433 56382433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 28 63 0 ENST00000343736.4:c.5533G>A p.Ala1845Thr p.A1845T ENST00000343736 1845 Gct/Act 0 +C10orf10 UCSF GRCh37 10 45473473 45473473 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 39 77 0 ENST00000298295.3:c.6G>A p.Arg2= p.R2= ENST00000298295 NM_007021.3 2 agG/agA 0 +C10orf12 UCSF GRCh37 10 98744434 98744434 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 72 157 0 ENST00000286067.2:c.3287G>A p.Ser1096Asn p.S1096N ENST00000286067 NM_015652.2 1096 aGc/aAc 0 +C10orf92 UCSF GRCh37 10 134647012 134647012 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 34 141 0 ENST00000368586.5:c.6967G>A p.Val2323Ile p.V2323I ENST00000368586 NM_001200049.2 2323 Gtt/Att 0 +C11orf2 UCSF GRCh37 11 64875733 64875733 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 18 6 26 0 ENST00000279281.3:c.790C>T p.Pro264Ser p.P264S ENST00000279281 NM_013265.3 264 Cct/Tct 0 +C11orf34 UCSF GRCh37 11 112123133 112123133 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 59 141 0 ENST00000338832.2:c.387-1G>A p.X129_splice ENST00000338832 NM_001145024.1 0 +C11orf41 UCSF GRCh37 11 33680437 33680437 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 42 33 54 0 ENST00000321505.4:c.5109T>C p.Asn1703= p.N1703= ENST00000321505 1703 aaT/aaC 0 +C11orf67 UCSF GRCh37 11 77553552 77553552 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 48 136 0 ENST00000393427.2:c.10C>T p.Pro4Ser p.P4S ENST00000393427 NM_024684.2 4 Cct/Tct 0 +C11orf80 UCSF GRCh37 11 66583523 66583523 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 98 202 0 ENST00000360962.4:c.1190-1G>A p.X397_splice ENST00000360962 NM_024650.3 0 +C12orf41 UCSF GRCh37 12 49054188 49054188 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 94 192 0 ENST00000420613.2:c.1188G>A p.Glu396= p.E396= ENST00000420613 NM_017822.3 396 gaG/gaA 0 +C12orf51 UCSF GRCh37 12 112605305 112605305 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 34 102 0 ENST00000550722.1:c.11912G>A p.Gly3971Glu p.G3971E ENST00000550722 NM_001109662.3 3971 gGg/gAg 0 +C13orf35 UCSF GRCh37 13 113333890 113333890 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 17 83 0 ENST00000356049.1:c.197G>A p.Gly66Asp p.G66D ENST00000356049 NM_207440.1 66 gGt/gAt 0 +C14orf169 UCSF GRCh37 14 73959400 73959400 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 56 48 111 0 ENST00000304061.5:n.1755G>A *585* ENST00000304061 0 +C14orf93 UCSF GRCh37 14 23467838 23467838 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 60 127 0 ENST00000299088.6:c.395G>A p.Gly132Glu p.G132E ENST00000299088 NM_001130708.1 132 gGg/gAg 0 +C15orf2 UCSF GRCh37 15 24921955 24921955 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 72 143 0 ENST00000329468.2:c.941G>A p.Ser314Asn p.S314N ENST00000329468 NM_018958.2 314 aGc/aAc 0 +C15orf38 UCSF GRCh37 15 90454051 90454051 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 44 77 0 ENST00000357484.5:c.93G>A p.Gly31= p.G31= ENST00000357484 NM_182616.2 31 ggG/ggA 0 +C15orf48 UCSF GRCh37 15 45723270 45723270 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 81 231 0 ENST00000344300.3:c.108G>A p.Trp36Ter p.W36* ENST00000344300 NM_032413.3 36 tgG/tgA 0 +C16orf11 UCSF GRCh37 16 613964 613964 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 8 13 0 ENST00000409413.3:c.670G>A p.Gly224Arg p.G224R ENST00000409413 NM_145270.2 224 Ggg/Agg 0 +C16orf79 UCSF GRCh37 16 2260557 2260557 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 27 37 0 ENST00000562360.1:c.146G>A p.Gly49Glu p.G49E ENST00000562360 49 gGa/gAa 0 +C16orf88 UCSF GRCh37 16 19722714 19722714 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 57 100 0 ENST00000219837.7:c.967G>A p.Asp323Asn p.D323N ENST00000219837 NM_001012991.2 323 Gat/Aat 0 +C16orf93 UCSF GRCh37 16 30770562 30770562 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 64 150 0 ENST00000543610.1:c.664C>T p.Leu222= p.L222= ENST00000543610 NM_001014979.2 222 Ctg/Ttg 0 +C17orf104 UCSF GRCh37 17 42745396 42745396 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 79 223 0 ENST00000409122.2:c.2117C>T p.Ser706Phe p.S706F ENST00000409122 NM_001145080.2 706 tCc/tTc 0 +C17orf108 UCSF GRCh37 17 26207345 26207345 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 85 210 0 ENST00000379102.3:c.174G>A p.Gln58= p.Q58= ENST00000379102 58 caG/caA 0 +C17orf61 UCSF GRCh37 17 7306428 7306428 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 71 141 0 ENST00000302422.3:c.299G>A p.Gly100Glu p.G100E ENST00000302422 NM_152766.3 100 gGa/gAa 0 +C17orf74 UCSF GRCh37 17 7330367 7330367 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 22 49 0 ENST00000333870.3:c.1057C>T p.Leu353Phe p.L353F ENST00000333870 NM_175734.4 353 Ctt/Ttt 0 +C19orf55 UCSF GRCh37 19 36258896 36258896 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 8 17 0 ENST00000396908.4:c.1149G>A p.Pro383= p.P383= ENST00000396908 NM_001039887.2 383 ccG/ccA 0 +C1orf101 UCSF GRCh37 1 244715903 244715903 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 103 214 0 ENST00000366534.4:c.816C>T p.Ile272= p.I272= ENST00000366534 NM_001130957.1 272 atC/atT 0 +C1orf141 UCSF GRCh37 1 67559268 67559268 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 54 119 0 ENST00000371006.1:c.623C>T p.Pro208Leu p.P208L ENST00000371006 208 cCc/cTc 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 74 50 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C1orf172 UCSF GRCh37 1 27278215 27278215 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 40 93 0 ENST00000320567.5:c.657C>T p.Phe219= p.F219= ENST00000320567 NM_152365.2 219 ttC/ttT 0 +C1orf174 UCSF GRCh37 1 3806606 3806606 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 69 163 0 ENST00000361605.3:c.650C>T p.Ser217Leu p.S217L ENST00000361605 NM_207356.2 217 tCa/tTa 0 +C1orf177 UCSF GRCh37 1 55273208 55273208 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 14 22 0 ENST00000371273.3:c.202G>A p.Gly68Ser p.G68S ENST00000371273 NM_001110533.1 68 Ggc/Agc 0 +C1orf185 UCSF GRCh37 1 51578242 51578242 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 48 137 0 ENST00000371759.2:c.122+1G>A p.X41_splice ENST00000371759 NM_001136508.1 0 +C1orf201 UCSF GRCh37 1 24687346 24687346 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 153 138 261 0 ENST00000337248.4:c.923G>A p.Gly308Asp p.G308D ENST00000337248 NM_001199014.1 308 gGc/gAc 0 +C1orf55 UCSF GRCh37 1 226176044 226176044 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 89 179 0 ENST00000272091.7:c.687G>A p.Glu229= p.E229= ENST00000272091 NM_152608.3 229 gaG/gaA 0 +C1orf9 UCSF GRCh37 1 172525047 172525047 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 46 122 0 ENST00000263688.3:c.327G>A p.Glu109= p.E109= ENST00000263688 NM_014283.3 109 gaG/gaA 0 +C1QC UCSF GRCh37 1 22974240 22974240 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 49 132 0 ENST00000374637.1:c.702C>T p.Asp234= p.D234= ENST00000374637 234 gaC/gaT 0 +C1QL1 UCSF GRCh37 17 43037688 43037688 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 53 93 0 ENST00000253407.3:c.645C>T p.Tyr215= p.Y215= ENST00000253407 NM_006688.3 215 taC/taT 0 +C1QTNF7 UCSF GRCh37 4 15444252 15444252 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 97 193 0 ENST00000429690.1:c.699G>A p.Gly233= p.G233= ENST00000429690 NM_001135171.1 233 ggG/ggA 0 +C1S UCSF GRCh37 12 7172428 7172428 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 57 128 0 ENST00000328916.3:c.542C>T p.Thr181Ile p.T181I ENST00000328916 NM_201442.2 181 aCt/aTt 0 +C20orf118 UCSF GRCh37 20 35515860 35515860 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 85 155 0 ENST00000217320.3:c.441C>T p.Val147= p.V147= ENST00000217320 NM_080628.1 147 gtC/gtT 0 +C20orf152 UCSF GRCh37 20 34571991 34571991 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 60 110 0 ENST00000373973.3:c.495G>A p.Lys165= p.K165= ENST00000373973 165 aaG/aaA 0 +C20orf173 UCSF GRCh37 20 34117064 34117064 + 5_prime_UTR_variant 5'UTR SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 33 76 0 ENST00000246199.2:c.-206C>T *69* ENST00000246199 0 +C20orf194 UCSF GRCh37 20 3296417 3296417 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 119 76 171 0 ENST00000252032.9:c.1555G>A p.Val519Ile p.V519I ENST00000252032 NM_001009984.2 519 Gta/Ata 0 +C20orf194 UCSF GRCh37 20 3305607 3305607 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 119 95 219 0 ENST00000252032.9:c.1197G>A p.Glu399= p.E399= ENST00000252032 NM_001009984.2 399 gaG/gaA 0 +C20orf203 UCSF GRCh37 20 31238448 31238448 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 13 20 0 ENST00000608990.1:n.944G>A *315* ENST00000608990 0 +C20orf4 UCSF GRCh37 20 34828399 34828399 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 69 163 0 ENST00000320849.4:c.609G>A p.Gly203= p.G203= ENST00000320849 NM_001271874.1 203 ggG/ggA 0 +C20orf43 UCSF GRCh37 20 55088414 55088414 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 13 29 0 ENST00000357348.5:c.611G>A p.Gly204Asp p.G204D ENST00000357348 NM_001283035.1 204 gGc/gAc 0 +C20orf54 UCSF GRCh37 20 745983 745983 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 67 43 87 0 ENST00000217254.7:c.436G>A p.Gly146Arg p.G146R ENST00000217254 NM_033409.3 146 Gga/Aga 0 +C20orf79 UCSF GRCh37 20 18794477 18794477 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 63 143 0 ENST00000377428.2:c.18C>T p.Asp6= p.D6= ENST00000377428 NM_178483.2 6 gaC/gaT 0 +C22orf13 UCSF GRCh37 22 24944004 24944004 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 51 77 0 ENST00000407471.3:c.166G>A p.Ala56Thr p.A56T ENST00000407471 NM_001284251.1 56 Gcc/Acc 0 +C22orf28 UCSF GRCh37 22 32793982 32793982 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 90 179 0 ENST00000216038.5:c.760G>A p.Val254Met p.V254M ENST00000216038 NM_014306.4 254 Gtg/Atg 0 +C2CD3 UCSF GRCh37 11 73789637 73789637 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 85 200 0 ENST00000334126.7:c.4126G>A p.Glu1376Lys p.E1376K ENST00000334126 NM_001286577.1 1376 Gaa/Aaa 0 +C2orf16 UCSF GRCh37 2 27799614 27799614 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 82 138 0 ENST00000408964.2:c.175G>A p.Asp59Asn p.D59N ENST00000408964 NM_032266.3 59 Gat/Aat 0 +C2orf40 UCSF GRCh37 2 106694240 106694240 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0054,snp132_rs117849769 P18_Rec Untested WXS Illumina HiSeq 129 106 196 0 ENST00000238044.3:c.305C>T p.Thr102Ile p.T102I ENST00000238044 NM_032411.2 102 aCc/aTc 0 +C2orf44 UCSF GRCh37 2 24260791 24260791 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 76 151 0 ENST00000295148.4:c.1574C>T p.Pro525Leu p.P525L ENST00000295148 NM_025203.2 525 cCc/cTc 0 +C2orf67 UCSF GRCh37 2 210896241 210896241 + stop_gained Nonsense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 194 151 283 1 ENST00000281772.9:c.2059G>T p.Gly687Ter p.G687* ENST00000281772 NM_152519.2 687 Gga/Tga 0 +C2orf68 UCSF GRCh37 2 85839061 85839061 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 13 23 0 ENST00000306336.5:c.47G>A p.Gly16Glu p.G16E ENST00000306336 NM_001013649.3 16 gGg/gAg 0 +C3orf25 UCSF GRCh37 3 129140431 129140431 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 74 197 0 ENST00000326085.3:c.265G>A p.Val89Ile p.V89I ENST00000326085 89 Gtt/Att 0 +C3orf30 UCSF GRCh37 3 118865880 118865880 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 122 85 163 0 ENST00000295622.1:c.844G>A p.Ala282Thr p.A282T ENST00000295622 NM_152539.2 282 Gct/Act 0 +C3orf30 UCSF GRCh37 3 118865621 118865621 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 131 243 0 ENST00000295622.1:c.585C>T p.Asp195= p.D195= ENST00000295622 NM_152539.2 195 gaC/gaT 0 +C4orf41 UCSF GRCh37 4 184628085 184628085 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 55 146 0 ENST00000334690.6:c.3181C>T p.Leu1061Phe p.L1061F ENST00000334690 NM_021942.5 1061 Ctc/Ttc 0 +C4orf46 UCSF GRCh37 4 159590829 159590829 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 75 146 0 ENST00000379205.4:c.278G>A p.Arg93His p.R93H ENST00000379205 NM_001008393.3 93 cGt/cAt 0 +C5 UCSF GRCh37 9 123742447 123742447 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 164 162 0 ENST00000223642.1:c.3572C>T p.Ser1191Phe p.S1191F ENST00000223642 NM_001735.2 1191 tCt/tTt 0 +C5AR1 UCSF GRCh37 19 47823952 47823952 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 66 176 0 ENST00000355085.3:c.918C>T p.Gly306= p.G306= ENST00000355085 NM_001736.3 306 ggC/ggT 0 +C5orf22 UCSF GRCh37 5 31538470 31538470 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 59 191 0 ENST00000325366.9:c.481C>T p.Pro161Ser p.P161S ENST00000325366 NM_018356.2 161 Cct/Tct 0 +C5orf51 UCSF GRCh37 5 41917241 41917241 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 130 67 188 0 ENST00000381647.2:c.725C>T p.Ala242Val p.A242V ENST00000381647 NM_175921.4 242 gCg/gTg 0 +C6orf132 UCSF GRCh37 6 42071557 42071557 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 22 55 0 ENST00000341865.4:c.3509G>A p.Gly1170Glu p.G1170E ENST00000341865 NM_001164446.1 1170 gGg/gAg 0 +C6orf165 UCSF GRCh37 6 88126492 88126492 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 51 125 0 ENST00000369562.4:c.578G>A p.Gly193Glu p.G193E ENST00000369562 NM_001031743.2 193 gGa/gAa 0 +C6orf174 UCSF GRCh37 6 127796620 127796620 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 50 154 0 ENST00000481848.2:c.2551G>A p.Asp851Asn p.D851N ENST00000481848 851 Gac/Aac 0 +C6orf211 UCSF GRCh37 6 151785748 151785748 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 27 67 0 ENST00000367294.3:c.553C>T p.Leu185= p.L185= ENST00000367294 NM_024573.1 185 Ctg/Ttg 0 +C6orf223 UCSF GRCh37 6 43970685 43970685 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 29 54 0 ENST00000336600.5:c.551C>T p.Pro184Leu p.P184L ENST00000336600 NM_001171992.1 184 cCc/cTc 0 +C6orf47 UCSF GRCh37 6 31627559 31627559 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 56 108 0 ENST00000375911.1:c.166C>T p.Pro56Ser p.P56S ENST00000375911 NM_021184.3 56 Ccc/Tcc 0 +C6orf70 UCSF GRCh37 6 170168254 170168254 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 47 116 0 ENST00000366773.3:c.1046G>A p.Gly349Glu p.G349E ENST00000366773 NM_018341.2 349 gGa/gAa 0 +C6orf97 UCSF GRCh37 6 151865852 151865852 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 79 205 0 ENST00000239374.7:c.588+1G>A p.X196_splice ENST00000239374 NM_025059.3 0 +C7orf47 UCSF GRCh37 7 100033560 100033560 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 22 0 ENST00000292330.2:c.362G>A p.Gly121Glu p.G121E ENST00000292330 NM_145030.2 121 gGg/gAg 0 +C7orf65 UCSF GRCh37 7 47698652 47698652 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 60 159 0 ENST00000408988.2:c.282C>T p.Thr94= p.T94= ENST00000408988 NM_001123065.1 94 acC/acT 0 +C8A UCSF GRCh37 1 57351790 57351790 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 85 210 0 ENST00000361249.3:c.1046G>A p.Gly349Asp p.G349D ENST00000361249 NM_000562.2 349 gGc/gAc 0 +C8orf37 UCSF GRCh37 8 96259901 96259901 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 61 155 0 ENST00000286688.5:c.568G>A p.Glu190Lys p.E190K ENST00000286688 NM_177965.3 190 Gaa/Aaa 0 +C8orf40 UCSF GRCh37 8 42407718 42407718 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 93 224 0 ENST00000414154.2:c.291C>T p.Asn97= p.N97= ENST00000414154 NM_138436.3 97 aaC/aaT 0 +C9orf172 UCSF GRCh37 9 139739664 139739664 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 12 27 0 ENST00000436881.1:c.798G>A p.Glu266= p.E266= ENST00000436881 NM_001080482.2 266 gaG/gaA 0 +C9orf93 UCSF GRCh37 9 15571644 15571644 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 24 105 215 0 ENST00000380701.3:c.64G>A p.Val22Ile p.V22I ENST00000380701 NM_173550.2 22 Gta/Ata 0 +CA14 UCSF GRCh37 1 150234659 150234659 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 144 102 195 0 ENST00000369111.4:c.359G>A p.Gly120Glu p.G120E ENST00000369111 NM_012113.1 120 gGg/gAg 0 +CA4 UCSF GRCh37 17 58235074 58235074 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 69 179 0 ENST00000300900.4:c.438G>A p.Glu146= p.E146= ENST00000300900 NM_000717.3 146 gaG/gaA 0 +CA5A UCSF GRCh37 16 87925507 87925507 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 19 55 0 ENST00000309893.2:c.672C>T p.Cys224= p.C224= ENST00000309893 NM_001739.1 224 tgC/tgT 0 +CABS1 UCSF GRCh37 4 71201071 71201072 + frameshift_variant Frame_Shift_Del DEL CA CA G NOVEL P18_Rec Untested WXS Illumina HiSeq 46 0 ENST00000273936.5:c.315_316delinsG p.Ile106Ter p.I106* ENST00000273936 NM_033122.3 105 tcCAta/tcGta 0 +CABYR UCSF GRCh37 18 21736260 21736260 + synonymous_variant,NMD_transcript_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 65 159 0 ENST00000463087.1:c.795G>A p.Gln265= p.Q265= ENST00000463087 265 caG/caA 0 +CACHD1 UCSF GRCh37 1 65131847 65131847 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 77 93 0 ENST00000290039.5:c.2231C>T p.Ser744Phe p.S744F ENST00000290039 NM_020925.2 744 tCc/tTc 0 +CACNA1A UCSF GRCh37 19 13470554 13470554 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 59 110 0 ENST00000360228.5:c.844C>T p.Pro282Ser p.P282S ENST00000360228 NM_001127222.1 282 Ccc/Tcc 0 +CACNA1D UCSF GRCh37 3 53707796 53707796 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 65 168 0 ENST00000350061.5:c.1220+643C>T *407* ENST00000350061 NM_001128840.2 0 +CACNA1E UCSF GRCh37 1 181762842 181762842 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 119 74 168 0 ENST00000367573.2:c.5940C>T p.Asn1980= p.N1980= ENST00000367573 NM_001205293.1 1980 aaC/aaT 0 +CACNA1F UCSF GRCh37 X 49088147 49088147 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 67 75 0 ENST00000376265.2:c.268G>A p.Glu90Lys p.E90K ENST00000376265 NM_005183.2 90 Gag/Aag 0 +CACNA1I UCSF GRCh37 22 40066139 40066139 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 95 221 0 ENST00000402142.3:c.4291G>A p.Val1431Met p.V1431M ENST00000402142 NM_021096.3 1431 Gtg/Atg 0 +CACNA1I UCSF GRCh37 22 40015336 40015336 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 48 121 0 ENST00000402142.3:c.504C>T p.Asp168= p.D168= ENST00000402142 NM_021096.3 168 gaC/gaT 0 +CACNA1S UCSF GRCh37 1 201018178 201018178 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 33 55 0 ENST00000362061.3:c.4291C>T p.Pro1431Ser p.P1431S ENST00000362061 NM_000069.2 1431 Ccc/Tcc 0 +CACNA1S UCSF GRCh37 1 201030429 201030429 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 59 98 0 ENST00000362061.3:c.3221C>T p.Thr1074Ile p.T1074I ENST00000362061 NM_000069.2 1074 aCt/aTt 0 +CACNA2D2 UCSF GRCh37 3 50402395 50402395 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 14 45 0 ENST00000479441.1:c.3236G>A p.Gly1079Asp p.G1079D ENST00000479441 1079 gGc/gAc 0 +CACNA2D2 UCSF GRCh37 3 50404897 50404897 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 29 73 0 ENST00000479441.1:c.2350C>T p.Pro784Ser p.P784S ENST00000479441 784 Ccc/Tcc 0 +CACNB1 UCSF GRCh37 17 37331830 37331830 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 48 121 0 ENST00000394303.3:c.1413G>A p.Glu471= p.E471= ENST00000394303 NM_000723.4 471 gaG/gaA 0 +CACNG1 UCSF GRCh37 17 65040959 65040959 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 30 71 0 ENST00000226021.3:c.183C>T p.Ile61= p.I61= ENST00000226021 NM_000727.3 61 atC/atT 0 +CADPS UCSF GRCh37 3 62478043 62478043 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 209 165 297 0 ENST00000383710.4:c.2806G>A p.Ala936Thr p.A936T ENST00000383710 NM_003716.3 936 Gcc/Acc 0 +CADPS2 UCSF GRCh37 7 121960334 121960334 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 208 173 339 0 ENST00000449022.2:c.3776C>T p.Thr1259Ile p.T1259I ENST00000449022 NM_017954.10 1259 aCt/aTt 0 +CADPS2 UCSF GRCh37 7 122377059 122377059 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 86 197 0 ENST00000449022.2:c.403C>T p.Gln135Ter p.Q135* ENST00000449022 NM_017954.10 135 Caa/Taa 0 +CALCOCO1 UCSF GRCh37 12 54107963 54107963 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 6 32 91 1 ENST00000550804.1:c.1545G>A p.Trp515Ter p.W515* ENST00000550804 515 tgG/tgA 0 +CALR3 UCSF GRCh37 19 16593283 16593283 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 54 133 0 ENST00000269881.3:c.896C>T p.Ala299Val p.A299V ENST00000269881 NM_145046.4 299 gCc/gTc 0 +CAMK1G UCSF GRCh37 1 209783195 209783195 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 58 117 0 ENST00000009105.1:c.749-1G>A p.X250_splice ENST00000009105 0 +CAMK2G UCSF GRCh37 10 75612997 75612997 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 41 98 0 ENST00000322680.3:c.228C>T p.Leu76= p.L76= ENST00000322680 NM_172170.4 76 ctC/ctT 0 +CAMTA1 UCSF GRCh37 1 7723491 7723491 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 71 142 0 ENST00000303635.7:c.884G>A p.Gly295Glu p.G295E ENST00000303635 NM_015215.2 295 gGg/gAg 0 +CAPN11 UCSF GRCh37 6 44140111 44140111 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 18 36 0 ENST00000398776.1:c.482G>A p.Arg161Lys p.R161K ENST00000398776 NM_007058.3 161 aGa/aAa 0 +CAPN12 UCSF GRCh37 19 39226149 39226149 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 14 47 0 ENST00000328867.4:c.1619C>T p.Ser540Phe p.S540F ENST00000328867 NM_144691.3 540 tCt/tTt 0 +CAPNS1 UCSF GRCh37 19 36633571 36633571 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 100 179 0 ENST00000246533.3:c.261C>T p.Tyr87= p.Y87= ENST00000246533 NM_001749.2 87 taC/taT 0 +CAPZA1 UCSF GRCh37 1 113189886 113189886 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 96 228 0 ENST00000263168.3:c.94G>A p.Val32Ile p.V32I ENST00000263168 NM_006135.2 32 Gta/Ata 0 +CARD11 UCSF GRCh37 7 2977541 2977541 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 39 76 0 ENST00000396946.4:c.1143G>A p.Gln381= p.Q381= ENST00000396946 NM_032415.4 381 caG/caA 0 +CARD16 UCSF GRCh37 11 104912389 104912389 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 96 221 0 ENST00000375706.2:c.332G>A p.Arg111Lys p.R111K ENST00000375706 NM_001017534.1 111 aGa/aAa 0 +CARM1 UCSF GRCh37 19 11024706 11024706 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 15 47 0 ENST00000327064.4:c.823G>A p.Ala275Thr p.A275T ENST00000327064 NM_199141.1 275 Gcc/Acc 0 +CARNS1 UCSF GRCh37 11 67192040 67192040 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 18 10 26 0 ENST00000307823.3:c.2452C>T p.Pro818Ser p.P818S ENST00000307823 NM_020811.1 818 Cct/Tct 0 +CASP5 UCSF GRCh37 11 104871090 104871090 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 171 102 235 0 ENST00000260315.3:c.850G>A p.Asp284Asn p.D284N ENST00000260315 284 Gat/Aat 0 +CASP8AP2 UCSF GRCh37 6 90571890 90571890 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 131 89 223 0 ENST00000551025.1:n.1899G>A *633* ENST00000551025 0 +CASS4 UCSF GRCh37 20 55012249 55012249 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 86 168 0 ENST00000360314.3:c.66C>T p.Asn22= p.N22= ENST00000360314 NM_001164116.1 22 aaC/aaT 0 +CASZ1 UCSF GRCh37 1 10720317 10720317 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 31 71 0 ENST00000377022.3:c.782C>T p.Thr261Ile p.T261I ENST00000377022 NM_001079843.2 261 aCc/aTc 0 +CATSPER2 UCSF GRCh37 15 43924482 43924482 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 72 133 1 ENST00000321596.5:c.1476C>T p.Pro492= p.P492= ENST00000321596 492 ccC/ccT 0 +CCBL2 UCSF GRCh37 1 89414918 89414918 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 68 153 0 ENST00000260508.4:c.997G>A p.Asp333Asn p.D333N ENST00000260508 NM_001008661.2 333 Gat/Aat 0 +CCBP2 UCSF GRCh37 3 42906810 42906810 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 176 98 245 0 ENST00000273145.2:c.816G>A p.Leu272= p.L272= ENST00000273145 272 ctG/ctA 0 +CCDC102B UCSF GRCh37 18 66504265 66504265 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 154 127 250 0 ENST00000319445.6:c.265G>A p.Glu89Lys p.E89K ENST00000319445 NM_001093729.1 89 Gaa/Aaa 0 +CCDC107 UCSF GRCh37 9 35661073 35661073 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 66 129 0 ENST00000426546.2:c.741G>A p.Arg247= p.R247= ENST00000426546 NM_001195201.1 247 cgG/cgA 0 +CCDC129 UCSF GRCh37 7 31691601 31691601 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 78 164 0 ENST00000407970.3:c.2760G>A p.Gln920= p.Q920= ENST00000407970 NM_194300.3 920 caG/caA 0 +CCDC132 UCSF GRCh37 7 92963441 92963441 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 159 104 214 0 ENST00000305866.5:c.1990G>A p.Gly664Arg p.G664R ENST00000305866 NM_017667.3 664 Gga/Aga 0 +CCDC134 UCSF GRCh37 22 42209287 42209287 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 62 163 0 ENST00000255784.5:c.330G>A p.Glu110= p.E110= ENST00000255784 NM_024821.2 110 gaG/gaA 0 +CCDC135 UCSF GRCh37 16 57756942 57756942 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 82 156 0 ENST00000360716.3:c.1437G>A p.Trp479Ter p.W479* ENST00000360716 479 tgG/tgA 0 +CCDC149 UCSF GRCh37 4 24810064 24810064 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 47 85 0 ENST00000504487.1:c.1537G>A p.Asp513Asn p.D513N ENST00000504487 NM_001130726.2 513 Gac/Aac 0 +CCDC36 UCSF GRCh37 3 49294536 49294536 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 116 255 0 ENST00000296449.5:c.1606C>T p.Leu536Phe p.L536F ENST00000296449 NM_178173.3 536 Ctc/Ttc 0 +CCDC57 UCSF GRCh37 17 80141668 80141668 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 87 155 0 ENST00000389641.4:c.1193C>T p.Ser398Phe p.S398F ENST00000389641 398 tCc/tTc 0 +CCDC58 UCSF GRCh37 3 122078754 122078754 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 65 161 0 ENST00000291458.5:c.397C>T p.Arg133Cys p.R133C ENST00000291458 NM_001017928.2 133 Cgc/Tgc 0 +CCDC75 UCSF GRCh37 2 37316927 37316927 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 18 78 185 0 ENST00000608836.1:c.192G>A p.Lys64= p.K64= ENST00000608836 64 aaG/aaA 0 +CCDC77 UCSF GRCh37 12 550148 550148 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 58 161 0 ENST00000239830.4:c.1306C>T p.Gln436Ter p.Q436* ENST00000239830 NM_032358.3 436 Caa/Taa 0 +CCDC83 UCSF GRCh37 11 85630413 85630413 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 87 187 0 ENST00000342404.3:c.1102C>T p.Leu368= p.L368= ENST00000342404 NM_001286159.1 368 Ctg/Ttg 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 100 79 161 0 ENST00000381259.1:c.412A>G p.Ile138Val p.I138V ENST00000381259 NM_018318.3 138 Att/Gtt 0 +CCNDBP1 UCSF GRCh37 15 43483770 43483770 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 67 150 0 ENST00000300213.4:c.757G>A p.Ala253Thr p.A253T ENST00000300213 NM_012142.4 253 Gcc/Acc 0 +CCNE1 UCSF GRCh37 19 30303917 30303917 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 32 76 0 ENST00000262643.3:c.153G>A p.Arg51= p.R51= ENST00000262643 NM_001238.2 51 agG/agA 0 +CCNH UCSF GRCh37 5 86700661 86700661 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 33 74 0 ENST00000256897.4:c.689G>A p.Ser230Asn p.S230N ENST00000256897 NM_001239.3 230 aGt/aAt 0 +CCNK UCSF GRCh37 14 99977096 99977096 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 8 21 0 ENST00000389879.5:c.1720G>A p.Gly574Arg p.G574R ENST00000389879 NM_001099402.1 574 Ggg/Agg 0 +CCNT1 UCSF GRCh37 12 49089613 49089613 + splice_acceptor_variant Splice_Site SNP C C T snp132_rs11833923 P18_Rec Untested WXS Illumina HiSeq 19 47 133 0 ENST00000261900.3:c.707-1G>A p.X236_splice ENST00000261900 NM_001240.3 0 +CCNT2 UCSF GRCh37 2 135696633 135696633 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 76 190 0 ENST00000264157.5:c.430+1G>A p.X144_splice ENST00000264157 NM_058241.2 0 +CCR8 UCSF GRCh37 3 39374006 39374006 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 169 117 271 0 ENST00000326306.4:c.184G>A p.Val62Ile p.V62I ENST00000326306 NM_005201.3 62 Gtc/Atc 0 +CCRL1 UCSF GRCh37 3 132320132 132320132 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 477 84 638 0 ENST00000249887.2:c.891C>T p.Cys297= p.C297= ENST00000249887 NM_016557.3 297 tgC/tgT 0 +CCT7 UCSF GRCh37 2 73466919 73466919 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 102 216 0 ENST00000258091.5:c.155G>A p.Gly52Asp p.G52D ENST00000258091 NM_006429.3 52 gGc/gAc 0 +CCT7 UCSF GRCh37 2 73471675 73471675 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 77 173 0 ENST00000258091.5:c.450G>A p.Glu150= p.E150= ENST00000258091 NM_006429.3 150 gaG/gaA 0 +CCT8L2 UCSF GRCh37 22 17073014 17073014 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 62 149 0 ENST00000359963.3:c.427G>A p.Val143Ile p.V143I ENST00000359963 NM_014406.4 143 Gtc/Atc 0 +CD101 UCSF GRCh37 1 117559965 117559965 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 76 173 0 ENST00000256652.4:c.1482C>T p.Phe494= p.F494= ENST00000256652 NM_004258.5 494 ttC/ttT 0 +CD207 UCSF GRCh37 2 71062662 71062662 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 52 110 0 ENST00000410009.3:c.150G>A p.Thr50= p.T50= ENST00000410009 NM_015717.3 50 acG/acA 0 +CD2BP2 UCSF GRCh37 16 30365523 30365523 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 95 220 0 ENST00000305596.3:c.199G>A p.Ala67Thr p.A67T ENST00000305596 NM_006110.2 67 Gcc/Acc 0 +CD300E UCSF GRCh37 17 72608796 72608796 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 43 96 0 ENST00000392619.1:c.695G>A p.Arg232Lys p.R232K ENST00000392619 NM_181449.2 232 aGa/aAa 0 +CD300LD UCSF GRCh37 17 72584665 72584665 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 112 75 166 0 ENST00000375352.1:c.364G>A p.Val122Met p.V122M ENST00000375352 NM_001115152.1 122 Gtg/Atg 0 +CD40 UCSF GRCh37 20 44750474 44750474 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 74 247 0 ENST00000372285.3:c.67C>T p.Pro23Ser p.P23S ENST00000372285 NM_001250.4 23 Ccc/Tcc 0 +CD5 UCSF GRCh37 11 60889194 60889194 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 38 86 0 ENST00000347785.3:c.917C>T p.Ala306Val p.A306V ENST00000347785 NM_014207.3 306 gCc/gTc 0 +CD6 UCSF GRCh37 11 60786787 60786787 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 11 56 0 ENST00000313421.7:c.2004C>T p.Ala668= p.A668= ENST00000313421 NM_006725.4 668 gcC/gcT 0 +CD79B UCSF GRCh37 17 62007564 62007564 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 51 107 0 ENST00000006750.3:c.300G>A p.Gln100= p.Q100= ENST00000006750 NM_021602.2 100 caG/caA 0 +CD83 UCSF GRCh37 6 14118245 14118245 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 36 13 56 0 ENST00000379153.3:c.102C>T p.Pro34= p.P34= ENST00000379153 NM_001040280.1 34 ccC/ccT 0 +CD86 UCSF GRCh37 3 121836932 121836932 + synonymous_variant Silent SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 52 128 0 ENST00000330540.2:c.885C>A p.Thr295= p.T295= ENST00000330540 NM_175862.4 295 acC/acA 0 +CD8A UCSF GRCh37 2 87013087 87013087 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 78 196 0 ENST00000283635.3:c.664G>A p.Val222Ile p.V222I ENST00000283635 NM_001768.6 222 Gtc/Atc 0 +CDADC1 UCSF GRCh37 13 49833592 49833592 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 161 77 231 0 ENST00000251108.6:c.363G>A p.Arg121= p.R121= ENST00000251108 NM_001193478.1 121 agG/agA 0 +CDADC1 UCSF GRCh37 13 49841626 49841626 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 49 125 0 ENST00000251108.6:c.431C>T p.Ala144Val p.A144V ENST00000251108 NM_001193478.1 144 gCt/gTt 0 +CDC16 UCSF GRCh37 13 115024859 115024859 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 43 141 0 ENST00000356221.3:c.1300G>A p.Ala434Thr p.A434T ENST00000356221 434 Gca/Aca 0 +CDC23 UCSF GRCh37 5 137534175 137534175 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 49 147 0 ENST00000394886.2:c.870G>A p.Arg290= p.R290= ENST00000394886 NM_004661.3 290 agG/agA 0 +CDC34 UCSF GRCh37 19 537137 537137 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 27 69 0 ENST00000215574.4:c.487G>A p.Asp163Asn p.D163N ENST00000215574 NM_004359.1 163 Gac/Aac 0 +CDC7 UCSF GRCh37 1 91973874 91973874 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 38 66 0 ENST00000234626.6:c.255G>A p.Glu85= p.E85= ENST00000234626 NM_001134419.1 85 gaG/gaA 0 +CDC7 UCSF GRCh37 1 91977338 91977338 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 68 139 0 ENST00000234626.6:c.430G>A p.Asp144Asn p.D144N ENST00000234626 NM_001134419.1 144 Gac/Aac 0 +CDCA4 UCSF GRCh37 14 105478160 105478160 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 65 170 0 ENST00000336219.3:c.107C>T p.Ser36Leu p.S36L ENST00000336219 NM_017955.3 36 tCg/tTg 0 +CDH2 UCSF GRCh37 18 25583066 25583066 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 73 183 0 ENST00000269141.3:c.915G>A p.Arg305= p.R305= ENST00000269141 NM_001792.3 305 agG/agA 0 +CDH2 UCSF GRCh37 18 25570165 25570165 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 69 203 0 ENST00000269141.3:c.1494C>T p.Ala498= p.A498= ENST00000269141 NM_001792.3 498 gcC/gcT 0 +CDH23 UCSF GRCh37 10 73556947 73556947 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 46 113 0 ENST00000224721.6:c.6814C>T p.Leu2272= p.L2272= ENST00000224721 NM_022124.5 2272 Cta/Tta 0 +CDH23 UCSF GRCh37 10 73437387 73437387 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 39 92 0 ENST00000224721.6:c.1704G>A p.Lys568= p.K568= ENST00000224721 NM_022124.5 568 aaG/aaA 0 +CDH23 UCSF GRCh37 10 73498296 73498296 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 106 178 0 ENST00000224721.6:c.4266G>A p.Arg1422= p.R1422= ENST00000224721 NM_022124.5 1422 cgG/cgA 0 +CDIPT UCSF GRCh37 16 29872497 29872497 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 49 136 0 ENST00000219789.6:c.262C>T p.Pro88Ser p.P88S ENST00000219789 NM_006319.3 88 Cct/Tct 0 +CDK12 UCSF GRCh37 17 37676277 37676277 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 140 89 203 0 ENST00000447079.4:c.3032C>T p.Ala1011Val p.A1011V ENST00000447079 NM_015083.1 1011 gCt/gTt 0 +CDK5 UCSF GRCh37 7 150754902 150754902 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 29 96 0 ENST00000485972.1:c.34G>A p.Glu12Lys p.E12K ENST00000485972 NM_004935.3 12 Gaa/Aaa 0 +CDRT1 UCSF GRCh37 17 15522780 15522780 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 235 133 468 0 ENST00000395906.3:c.47G>A p.Cys16Tyr p.C16Y ENST00000395906 NM_006382.3 16 tGt/tAt 0 +CDRT1 UCSF GRCh37 17 15496780 15496780 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 228 170 349 0 ENST00000395906.3:c.1877T>A p.Leu626His p.L626H ENST00000395906 NM_006382.3 626 cTc/cAc 0 +CEACAM20 UCSF GRCh37 19 45021256 45021256 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 53 146 0 ENST00000454753.1:n.1339G>A *447* ENST00000454753 0 +CEACAM21 UCSF GRCh37 19 42092212 42092212 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 44 113 0 ENST00000401445.2:c.870C>T p.Ser290= p.S290= ENST00000401445 290 agC/agT 0 +CELSR3 UCSF GRCh37 3 48684203 48684203 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 27 59 0 ENST00000164024.4:c.7288G>A p.Gly2430Ser p.G2430S ENST00000164024 NM_001407.2 2430 Ggt/Agt 0 +CELSR3 UCSF GRCh37 3 48697265 48697265 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 63 142 0 ENST00000164024.4:c.2803G>A p.Asp935Asn p.D935N ENST00000164024 NM_001407.2 935 Gac/Aac 0 +CELSR3 UCSF GRCh37 3 48698563 48698563 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 16 18 37 0 ENST00000164024.4:c.1505A>G p.Asp502Gly p.D502G ENST00000164024 NM_001407.2 502 gAc/gGc 0 +CEMP1 UCSF GRCh37 16 2580808 2580808 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 19 45 0 ENST00000567119.1:c.267G>A p.Gly89= p.G89= ENST00000567119 NM_001048212.3 89 ggG/ggA 0 +CENPB UCSF GRCh37 20 3766747 3766747 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 26 37 0 ENST00000379751.4:c.384G>A p.Arg128= p.R128= ENST00000379751 NM_001810.5 128 cgG/cgA 0 +CENPE UCSF GRCh37 4 104066777 104066777 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 72 172 0 ENST00000265148.3:c.4475C>T p.Thr1492Ile p.T1492I ENST00000265148 NM_001813.2 1492 aCt/aTt 0 +CENPF UCSF GRCh37 1 214814907 214814907 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 81 199 0 ENST00000366955.3:c.3226G>A p.Glu1076Lys p.E1076K ENST00000366955 NM_016343.3 1076 Gaa/Aaa 0 +CENPT UCSF GRCh37 16 67862212 67862212 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 34 38 90 0 ENST00000440851.2:c.1644C>T p.Ile548= p.I548= ENST00000440851 548 atC/atT 0 +CEP112 UCSF GRCh37 17 64092721 64092721 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 41 97 0 ENST00000392769.2:c.672G>A p.Lys224= p.K224= ENST00000392769 NM_145036.3 224 aaG/aaA 0 +CEP135 UCSF GRCh37 4 56876058 56876058 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 115 104 176 0 ENST00000257287.4:c.2494A>G p.Arg832Gly p.R832G ENST00000257287 NM_025009.4 832 Aga/Gga 0 +CEP170 UCSF GRCh37 1 243327806 243327806 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 77 316 0 ENST00000366542.1:c.3456G>A p.Gln1152= p.Q1152= ENST00000366542 NM_014812.2 1152 caG/caA 0 +CEP192 UCSF GRCh37 18 13096183 13096183 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 65 145 0 ENST00000506447.1:c.6434G>A p.Cys2145Tyr p.C2145Y ENST00000506447 NM_032142.3 2145 tGt/tAt 0 +CEP290 UCSF GRCh37 12 88500814 88500814 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 64 155 0 ENST00000552810.1:c.2545G>A p.Asp849Asn p.D849N ENST00000552810 NM_025114.3 849 Gat/Aat 0 +CEP78 UCSF GRCh37 9 80881440 80881440 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 59 144 0 ENST00000424347.2:c.1880G>A p.Gly627Glu p.G627E ENST00000424347 627 gGa/gAa 0 +CES3 UCSF GRCh37 16 67006937 67006937 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 52 106 0 ENST00000303334.4:c.1701C>T p.Ala567= p.A567= ENST00000303334 NM_024922.5 567 gcC/gcT 0 +CFHR3 UCSF GRCh37 1 196749019 196749019 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 68 137 0 ENST00000367425.4:c.346C>T p.Pro116Ser p.P116S ENST00000367425 NM_021023.5 116 Cct/Tct 0 +CHAF1A UCSF GRCh37 19 4423333 4423333 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 102 193 0 ENST00000301280.5:c.1249G>A p.Ala417Thr p.A417T ENST00000301280 NM_005483.2 417 Gct/Act 0 +CHAT UCSF GRCh37 10 50873074 50873074 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 69 156 0 ENST00000337653.2:c.2229C>T p.Ser743= p.S743= ENST00000337653 NM_020549.4 743 agC/agT 0 +CHD1L UCSF GRCh37 1 146765378 146765378 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 147 359 0 ENST00000369258.4:c.2478G>A p.Lys826= p.K826= ENST00000369258 NM_001256336.1 826 aaG/aaA 0 +CHD6 UCSF GRCh37 20 40065937 40065937 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 65 138 0 ENST00000373233.3:c.4045G>A p.Val1349Ile p.V1349I ENST00000373233 NM_032221.4 1349 Gta/Ata 0 +CHD6 UCSF GRCh37 20 40127937 40127937 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 22 55 0 ENST00000373233.3:c.913G>A p.Glu305Lys p.E305K ENST00000373233 NM_032221.4 305 Gag/Aag 0 +CHD9 UCSF GRCh37 16 53308204 53308204 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 169 128 237 0 ENST00000398510.3:c.4957G>A p.Val1653Ile p.V1653I ENST00000398510 1653 Gtt/Att 0 +CHI3L2 UCSF GRCh37 1 111781529 111781529 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 81 185 0 ENST00000369748.4:c.893C>T p.Ser298Phe p.S298F ENST00000369748 NM_004000.2 298 tCt/tTt 0 +CHIT1 UCSF GRCh37 1 203192374 203192374 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 79 175 0 ENST00000367229.1:c.494C>T p.Ala165Val p.A165V ENST00000367229 NM_003465.2 165 gCc/gTc 0 +CHPF2 UCSF GRCh37 7 150934555 150934555 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 49 111 0 ENST00000035307.2:c.1107C>T p.Arg369= p.R369= ENST00000035307 NM_019015.1 369 cgC/cgT 0 +CHRM1 UCSF GRCh37 11 62677564 62677564 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 59 143 0 ENST00000306960.3:c.1009G>A p.Ala337Thr p.A337T ENST00000306960 NM_000738.2 337 Gct/Act 0 +CHRM2 UCSF GRCh37 7 136700241 136700241 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 65 113 0 ENST00000320658.5:c.629C>T p.Ser210Phe p.S210F ENST00000320658 NM_001006632.1 210 tCc/tTc 0 +CHST11 UCSF GRCh37 12 105150931 105150931 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 45 114 0 ENST00000303694.5:c.409G>A p.Val137Ile p.V137I ENST00000303694 NM_018413.5 137 Gtc/Atc 0 +CHST12 UCSF GRCh37 7 2472470 2472470 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 55 95 0 ENST00000258711.6:c.196G>A p.Val66Ile p.V66I ENST00000258711 NM_001243794.1 66 Gtc/Atc 0 +CHST13 UCSF GRCh37 3 126260857 126260857 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.014,1000g2011may_all_0.0310,snp132_rs58576050 P18_Rec Untested WXS Illumina HiSeq 13 15 25 0 ENST00000319340.2:c.462C>T p.Asp154= p.D154= ENST00000319340 NM_152889.2 154 gaC/gaT 0 +CHST4 UCSF GRCh37 16 71570604 71570604 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 93 171 0 ENST00000338482.5:c.24G>A p.Lys8= p.K8= ENST00000338482 8 aaG/aaA 0 +CHST5 UCSF GRCh37 16 75564161 75564161 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 17 28 0 ENST00000336257.3:c.122C>T p.Thr41Ile p.T41I ENST00000336257 NM_024533.4 41 aCc/aTc 0 +CIT UCSF GRCh37 12 120295477 120295477 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 156 103 248 0 ENST00000261833.7:c.264G>A p.Gln88= p.Q88= ENST00000261833 NM_007174.2 88 caG/caA 0 +CITED2 UCSF GRCh37 6 139695002 139695002 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 12 34 0 ENST00000367651.2:c.80G>A p.Arg27His p.R27H ENST00000367651 NM_006079.4 27 cGc/cAc 0 +CKAP2 UCSF GRCh37 13 53039430 53039430 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 76 197 0 ENST00000378037.5:c.1309G>A p.Gly437Arg p.G437R ENST00000378037 NM_018204.3 437 Gga/Aga 0 +CKAP5 UCSF GRCh37 11 46819722 46819722 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 144 109 202 0 ENST00000529230.1:c.1084G>A p.Val362Ile p.V362I ENST00000529230 362 Gtt/Att 0 +CKMT2 UCSF GRCh37 5 80555039 80555039 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 45 110 0 ENST00000254035.4:c.980C>T p.Ala327Val p.A327V ENST00000254035 327 gCt/gTt 0 +CLCN1 UCSF GRCh37 7 143043243 143043243 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 41 85 0 ENST00000343257.2:c.2183C>T p.Ser728Phe p.S728F ENST00000343257 NM_000083.2 728 tCc/tTc 0 +CLCN2 UCSF GRCh37 3 184076576 184076576 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 22 39 0 ENST00000265593.4:c.246C>T p.Phe82= p.F82= ENST00000265593 NM_004366.5 82 ttC/ttT 0 +CLCN3 UCSF GRCh37 4 170613362 170613362 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 159 136 274 0 ENST00000513761.1:c.827G>A p.Gly276Asp p.G276D ENST00000513761 NM_001829.3 276 gGt/gAt 0 +CLCN7 UCSF GRCh37 16 1500513 1500513 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 5 20 0 ENST00000382745.4:c.1602C>T p.Tyr534= p.Y534= ENST00000382745 NM_001287.5 534 taC/taT 0 +CLDN1 UCSF GRCh37 3 190030796 190030796 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 188 132 269 0 ENST00000295522.3:c.253G>A p.Val85Met p.V85M ENST00000295522 NM_021101.4 85 Gtg/Atg 0 +CLEC9A UCSF GRCh37 12 10217414 10217414 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 76 165 0 ENST00000355819.1:c.555C>T p.Arg185= p.R185= ENST00000355819 NM_207345.2 185 cgC/cgT 0 +CLINT1 UCSF GRCh37 5 157221923 157221923 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 31 91 0 ENST00000411809.2:c.1070G>A p.Gly357Asp p.G357D ENST00000411809 NM_014666.3 357 gGc/gAc 0 +CLIP1 UCSF GRCh37 12 122862435 122862435 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 200 147 277 0 ENST00000540338.1:c.158A>G p.Glu53Gly p.E53G ENST00000540338 53 gAa/gGa 0 +CLMP UCSF GRCh37 11 122968596 122968596 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 86 167 0 ENST00000448775.2:c.93C>T p.Val31= p.V31= ENST00000448775 NM_024769.2 31 gtC/gtT 0 +CLSTN2 UCSF GRCh37 3 140280982 140280982 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 52 136 0 ENST00000458420.3:c.2044C>T p.Pro682Ser p.P682S ENST00000458420 NM_022131.2 682 Ccc/Tcc 0 +CLVS2 UCSF GRCh37 6 123318973 123318973 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 52 162 0 ENST00000275162.5:c.51C>T p.Arg17= p.R17= ENST00000275162 NM_001010852.3 17 cgC/cgT 0 +CMTM4 UCSF GRCh37 16 66651192 66651192 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 48 68 0 ENST00000330687.4:c.693G>A p.Trp231Ter p.W231* ENST00000330687 NM_181521.2 231 tgG/tgA 0 +CMYA5 UCSF GRCh37 5 79035216 79035216 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 62 141 0 ENST00000446378.2:c.10628G>A p.Ser3543Asn p.S3543N ENST00000446378 NM_153610.3 3543 aGt/aAt 0 +CMYA5 UCSF GRCh37 5 79041083 79041083 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 104 216 0 ENST00000446378.2:c.10773G>A p.Gln3591= p.Q3591= ENST00000446378 NM_153610.3 3591 caG/caA 0 +CNGB1 UCSF GRCh37 16 57954336 57954336 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 52 129 0 ENST00000251102.8:c.1756C>T p.Leu586Phe p.L586F ENST00000251102 NM_001297.4 586 Ctc/Ttc 0 +CNKSR1 UCSF GRCh37 1 26510770 26510770 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 92 155 0 ENST00000374253.5:c.1013C>T p.Ala338Val p.A338V ENST00000374253 NM_006314.2 338 gCc/gTc 0 +CNNM4 UCSF GRCh37 2 97475190 97475190 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 49 102 0 ENST00000377075.2:c.2264C>T p.Thr755Ile p.T755I ENST00000377075 NM_020184.3 755 aCc/aTc 0 +CNNM4 UCSF GRCh37 2 97427097 97427097 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 70 164 0 ENST00000377075.2:c.361G>A p.Val121Ile p.V121I ENST00000377075 NM_020184.3 121 Gtc/Atc 0 +CNTN3 UCSF GRCh37 3 74349022 74349022 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 42 133 0 ENST00000263665.6:c.2163G>A p.Trp721Ter p.W721* ENST00000263665 NM_020872.1 721 tgG/tgA 0 +CNTNAP4 UCSF GRCh37 16 76389299 76389299 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 92 75 159 0 ENST00000478060.1:c.206T>C p.Val69Ala p.V69A ENST00000478060 NM_138994.3 69 gTg/gCg 0 +CNTRL UCSF GRCh37 9 123886221 123886221 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 119 143 0 ENST00000238341.5:c.1663G>A p.Ala555Thr p.A555T ENST00000238341 NM_007018.4 555 Gct/Act 0 +CNTROB UCSF GRCh37 17 7837463 7837463 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 73 175 0 ENST00000563694.1:c.278C>T p.Ser93Phe p.S93F ENST00000563694 NM_053051.3 93 tCt/tTt 0 +CNTROB UCSF GRCh37 17 7847867 7847867 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 56 89 0 ENST00000563694.1:c.1645C>T p.Leu549= p.L549= ENST00000563694 NM_053051.3 549 Ctg/Ttg 0 +COIL UCSF GRCh37 17 55027908 55027908 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 109 212 0 ENST00000240316.4:c.695G>A p.Arg232Lys p.R232K ENST00000240316 NM_004645.2 232 aGg/aAg 0 +COL16A1 UCSF GRCh37 1 32122668 32122668 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 69 126 0 ENST00000373672.3:c.4022G>A p.Gly1341Asp p.G1341D ENST00000373672 NM_001856.3 1341 gGc/gAc 0 +COL17A1 UCSF GRCh37 10 105824195 105824195 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 29 49 0 ENST00000353479.5:c.766+1G>A p.X256_splice ENST00000353479 NM_000494.3 0 +COL20A1 UCSF GRCh37 20 61951530 61951530 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 46 0 ENST00000358894.6:c.3056C>T p.Pro1019Leu p.P1019L ENST00000358894 NM_020882.2 1019 cCc/cTc 0 +COL20A1 UCSF GRCh37 20 61959774 61959774 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 40 71 0 ENST00000358894.6:c.3705G>A p.Leu1235= p.L1235= ENST00000358894 NM_020882.2 1235 ctG/ctA 0 +COL21A1 UCSF GRCh37 6 55989066 55989066 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 86 92 139 0 ENST00000244728.5:c.1675G>A p.Ala559Thr p.A559T ENST00000244728 NM_030820.3 559 Gct/Act 0 +COL21A1 UCSF GRCh37 6 56031718 56031718 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 67 154 0 ENST00000244728.5:c.1264G>A p.Glu422Lys p.E422K ENST00000244728 NM_030820.3 422 Gag/Aag 0 +COL22A1 UCSF GRCh37 8 139606353 139606353 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 30 95 0 ENST00000303045.6:c.4522G>A p.Asp1508Asn p.D1508N ENST00000303045 NM_152888.1 1508 Gat/Aat 0 +COL22A1 UCSF GRCh37 8 139661982 139661982 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 34 65 0 ENST00000303045.6:c.3373C>T p.Pro1125Ser p.P1125S ENST00000303045 NM_152888.1 1125 Cct/Tct 0 +COL28A1 UCSF GRCh37 7 7410432 7410432 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 70 159 0 ENST00000399429.3:c.2990C>T p.Pro997Leu p.P997L ENST00000399429 NM_001037763.2 997 cCt/cTt 0 +COL28A1 UCSF GRCh37 7 7477036 7477036 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 29 60 0 ENST00000399429.3:c.1780C>T p.Pro594Ser p.P594S ENST00000399429 NM_001037763.2 594 Cct/Tct 0 +COL3A1 UCSF GRCh37 2 189864614 189864614 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 3 11 0 ENST00000304636.3:c.2276G>A p.Gly759Asp p.G759D ENST00000304636 NM_000090.3 759 gGc/gAc 0 +COL4A1 UCSF GRCh37 13 110815821 110815821 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 15 69 0 ENST00000375820.4:c.4238C>T p.Ala1413Val p.A1413V ENST00000375820 NM_001845.4 1413 gCc/gTc 0 +COL4A2 UCSF GRCh37 13 111102651 111102651 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 42 95 0 ENST00000360467.5:c.1190-1G>A p.X397_splice ENST00000360467 NM_001846.2 0 +COL5A2 UCSF GRCh37 2 189927939 189927939 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 72 145 0 ENST00000374866.3:c.1828C>T p.Gln610Ter p.Q610* ENST00000374866 NM_000393.3 610 Cag/Tag 0 +COL6A3 UCSF GRCh37 2 238290014 238290014 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 75 192 1 ENST00000295550.4:c.1441C>T p.Leu481Phe p.L481F ENST00000295550 NM_004369.3 481 Ctt/Ttt 0 +COL7A1 UCSF GRCh37 3 48619761 48619761 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 60 148 0 ENST00000328333.8:c.4630G>A p.Val1544Met p.V1544M ENST00000328333 NM_000094.3 1544 Gtg/Atg 0 +COL8A1 UCSF GRCh37 3 99514361 99514361 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 6 24 0 ENST00000261037.3:c.1616G>A p.Gly539Glu p.G539E ENST00000261037 NM_001850.4 539 gGa/gAa 0 +COL8A2 UCSF GRCh37 1 36564612 36564612 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 28 60 0 ENST00000303143.4:c.670G>A p.Ala224Thr p.A224T ENST00000303143 NM_005202.2 224 Gcc/Acc 0 +COMP UCSF GRCh37 19 18896951 18896951 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 68 115 0 ENST00000222271.2:c.1313G>A p.Gly438Glu p.G438E ENST00000222271 NM_000095.2 438 gGa/gAa 0 +COPS3 UCSF GRCh37 17 17171289 17171289 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 75 116 0 ENST00000268717.5:c.351C>T p.Pro117= p.P117= ENST00000268717 NM_003653.3 117 ccC/ccT 0 +COPS4 UCSF GRCh37 4 83971051 83971051 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 122 91 247 0 ENST00000264389.2:c.324G>A p.Gln108= p.Q108= ENST00000264389 NM_016129.2 108 caG/caA 0 +CORO7 UCSF GRCh37 16 4414887 4414887 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 10 28 0 ENST00000251166.4:c.933G>A p.Gly311= p.G311= ENST00000251166 NM_024535.4 311 ggG/ggA 0 +CPA2 UCSF GRCh37 7 129909590 129909590 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 139 147 0 ENST00000222481.4:c.235G>A p.Val79Met p.V79M ENST00000222481 NM_001869.2 79 Gtg/Atg 0 +CPA4 UCSF GRCh37 7 129939224 129939224 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 132 130 0 ENST00000222482.4:c.265G>A p.Val89Met p.V89M ENST00000222482 NM_016352.3 89 Gtg/Atg 0 +CPEB4 UCSF GRCh37 5 173372078 173372078 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 126 227 0 ENST00000265085.5:c.1391G>A p.Gly464Glu p.G464E ENST00000265085 NM_030627.2 464 gGg/gAg 0 +CPLX3 UCSF GRCh37 15 75120402 75120402 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 11 40 0 ENST00000395018.4:c.192G>A p.Gln64= p.Q64= ENST00000395018 NM_001030005.2 64 caG/caA 0 +CPNE8 UCSF GRCh37 12 39087557 39087557 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 85 202 0 ENST00000331366.5:c.1045G>A p.Glu349Lys p.E349K ENST00000331366 NM_153634.2 349 Gaa/Aaa 0 +CPNE8 UCSF GRCh37 12 39069519 39069519 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 49 101 0 ENST00000331366.5:c.1432G>A p.Ala478Thr p.A478T ENST00000331366 NM_153634.2 478 Gca/Aca 0 +CRAT UCSF GRCh37 9 131864202 131864202 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 48 107 0 ENST00000318080.2:c.765C>T p.His255= p.H255= ENST00000318080 NM_001257363.1 255 caC/caT 0 +CREB1 UCSF GRCh37 2 208420369 208420369 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 43 80 0 ENST00000432329.2:c.10G>A p.Glu4Lys p.E4K ENST00000432329 NM_134442.3 4 Gaa/Aaa 0 +CREB3L2 UCSF GRCh37 7 137569861 137569861 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 77 53 103 0 ENST00000330387.6:c.1150G>A p.Val384Met p.V384M ENST00000330387 NM_194071.3 384 Gtg/Atg 0 +CREBBP UCSF GRCh37 16 3778942 3778942 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 17 15 0 ENST00000262367.5:c.6106C>T p.Pro2036Ser p.P2036S ENST00000262367 NM_004380.2 2036 Ccc/Tcc 0 +CRELD1 UCSF GRCh37 3 9976276 9976276 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 25 95 0 ENST00000383811.3:c.154C>T p.Leu52= p.L52= ENST00000383811 NM_015513.4 52 Ctg/Ttg 0 +CRHBP UCSF GRCh37 5 76264612 76264612 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 84 171 0 ENST00000274368.4:c.871G>A p.Val291Ile p.V291I ENST00000274368 NM_001882.3 291 Gta/Ata 0 +CRLF1 UCSF GRCh37 19 18709378 18709378 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 38 132 0 ENST00000392386.3:c.561C>T p.Tyr187= p.Y187= ENST00000392386 NM_004750.4 187 taC/taT 0 +CROCC UCSF GRCh37 1 17292500 17292500 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 35 79 0 ENST00000375541.5:c.4582C>T p.Leu1528Phe p.L1528F ENST00000375541 NM_014675.3 1528 Ctt/Ttt 0 +CSE1L UCSF GRCh37 20 47688968 47688968 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 117 79 196 0 ENST00000262982.2:c.914G>A p.Gly305Asp p.G305D ENST00000262982 NM_001316.3 305 gGt/gAt 0 +CSF1R UCSF GRCh37 5 149434822 149434822 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 46 89 0 ENST00000286301.3:c.2632C>T p.Pro878Ser p.P878S ENST00000286301 NM_005211.3 878 Cct/Tct 0 +CSF3R UCSF GRCh37 1 36932337 36932337 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 60 130 0 ENST00000361632.4:c.2132C>T p.Ser711Phe p.S711F ENST00000361632 711 tCc/tTc 0 +CSF3R UCSF GRCh37 1 36934774 36934774 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 45 74 0 ENST00000361632.4:c.1559C>T p.Ala520Val p.A520V ENST00000361632 520 gCc/gTc 0 +CSF3R UCSF GRCh37 1 36933197 36933197 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 28 48 0 ENST00000361632.4:c.1920C>T p.Thr640= p.T640= ENST00000361632 640 acC/acT 0 +CSNK1A1 UCSF GRCh37 5 148897381 148897381 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 116 236 0 ENST00000377843.2:c.456+2472C>T *152* ENST00000377843 NM_001271741.1 0 +CSPG4 UCSF GRCh37 15 75977233 75977233 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 71 181 0 ENST00000308508.5:c.4293C>T p.Arg1431= p.R1431= ENST00000308508 NM_001897.4 1431 cgC/cgT 0 +CST7 UCSF GRCh37 20 24937999 24937999 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 164 110 267 0 ENST00000480798.1:c.147C>T p.Val49= p.V49= ENST00000480798 NM_003650.3 49 gtC/gtT 0 +CSTF2 UCSF GRCh37 X 100079185 100079185 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 68 85 0 ENST00000372972.2:c.641G>A p.Gly214Asp p.G214D ENST00000372972 NM_001325.2 214 gGc/gAc 0 +CTIF UCSF GRCh37 18 46284610 46284610 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 93 160 1 ENST00000256413.3:c.905C>T p.Thr302Ile p.T302I ENST00000256413 NM_014772.2 302 aCc/aTc 0 +CTNNAL1 UCSF GRCh37 9 111705072 111705072 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 80 173 0 ENST00000325551.4:c.2182G>A p.Asp728Asn p.D728N ENST00000325551 NM_003798.2 728 Gac/Aac 0 +CTSA UCSF GRCh37 20 44520380 44520380 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 87 147 0 ENST00000191018.5:c.173G>A p.Gly58Asp p.G58D ENST00000191018 58 gGc/gAc 0 +CTSC UCSF GRCh37 11 88068104 88068104 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 56 130 0 ENST00000227266.5:c.318+1G>A p.X106_splice ENST00000227266 NM_001814.4 0 +CTSL2 UCSF GRCh37 9 99795242 99795242 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 46 96 0 ENST00000259470.5:c.994C>T p.Pro332Ser p.P332S ENST00000259470 NM_001333.3 332 Ccc/Tcc 0 +CUBN UCSF GRCh37 10 16870808 16870808 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 87 133 0 ENST00000377833.4:c.10760G>A p.Gly3587Glu p.G3587E ENST00000377833 NM_001081.3 3587 gGa/gAa 0 +CUBN UCSF GRCh37 10 16962047 16962047 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 38 116 0 ENST00000377833.4:c.6736G>A p.Asp2246Asn p.D2246N ENST00000377833 NM_001081.3 2246 Gat/Aat 0 +CUBN UCSF GRCh37 10 17145230 17145230 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 159 54 101 0 ENST00000377833.4:c.1424G>A p.Gly475Glu p.G475E ENST00000377833 NM_001081.3 475 gGa/gAa 0 +CUL1 UCSF GRCh37 7 148480875 148480875 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 80 154 0 ENST00000325222.4:c.1084G>A p.Asp362Asn p.D362N ENST00000325222 NM_003592.2 362 Gac/Aac 0 +CUL3 UCSF GRCh37 2 225339030 225339030 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 64 164 0 ENST00000264414.4:c.2239G>A p.Gly747Arg p.G747R ENST00000264414 NM_003590.4 747 Gga/Aga 0 +CUL3 UCSF GRCh37 2 225342968 225342968 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 83 135 0 ENST00000264414.4:c.2124G>A p.Val708= p.V708= ENST00000264414 NM_003590.4 708 gtG/gtA 0 +CXCL1 UCSF GRCh37 4 74735207 74735207 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 8 18 0 ENST00000395761.3:c.20C>T p.Ser7Phe p.S7F ENST00000395761 NM_001511.3 7 tCc/tTc 0 +CXCL11 UCSF GRCh37 4 76957089 76957089 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 97 185 0 ENST00000306621.3:c.52G>A p.Val18Ile p.V18I ENST00000306621 NM_005409.4 18 Gtt/Att 0 +CYB561D2 UCSF GRCh37 3 50390813 50390813 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 42 127 0 ENST00000232508.5:c.307C>T p.Leu103Phe p.L103F ENST00000232508 NM_007022.3 103 Ctt/Ttt 0 +CYB5R1 UCSF GRCh37 1 202931800 202931800 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 52 105 0 ENST00000367249.4:c.773C>T p.Thr258Ile p.T258I ENST00000367249 NM_016243.2 258 aCt/aTt 0 +CYFIP2 UCSF GRCh37 5 156787375 156787375 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 93 230 0 ENST00000521420.1:c.2825C>T p.Ser942Phe p.S942F ENST00000521420 942 tCc/tTc 0 +CYP2C19 UCSF GRCh37 10 96522537 96522537 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 133 261 0 ENST00000371321.3:c.75G>A p.Gly25= p.G25= ENST00000371321 NM_000769.1 25 ggG/ggA 0 +CYP2D6 UCSF GRCh37 22 42523985 42523985 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 41 111 0 ENST00000360608.5:c.844G>A p.Ala282Thr p.A282T ENST00000360608 NM_000106.5 282 Gcc/Acc 0 +CYP2W1 UCSF GRCh37 7 1028323 1028323 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 16 28 0 ENST00000308919.7:c.1338G>A p.Leu446= p.L446= ENST00000308919 NM_017781.2 446 ctG/ctA 0 +CYP4A11 UCSF GRCh37 1 47398447 47398447 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 251 169 337 0 ENST00000310638.4:c.1350C>T p.Phe450= p.F450= ENST00000310638 NM_000778.3 450 ttC/ttT 0 +CYP4B1 UCSF GRCh37 1 47283665 47283665 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 107 224 0 ENST00000271153.4:c.1233C>T p.Ala411= p.A411= ENST00000271153 411 gcC/gcT 0 +DAB2IP UCSF GRCh37 9 124535010 124535010 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 46 77 0 ENST00000408936.3:c.2203C>T p.Pro735Ser p.P735S ENST00000408936 735 Cct/Tct 0 +DACH1 UCSF GRCh37 13 72440792 72440792 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 24 0 ENST00000305425.4:c.116C>T p.Ser39Phe p.S39F ENST00000305425 NM_080759.4 39 tCt/tTt 0 +DACT1 UCSF GRCh37 14 59107532 59107532 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 157 120 255 0 ENST00000335867.4:c.424G>A p.Asp142Asn p.D142N ENST00000335867 142 Gat/Aat 0 +DAG1 UCSF GRCh37 3 49568292 49568292 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 50 86 0 ENST00000308775.2:c.348C>T p.Thr116= p.T116= ENST00000308775 NM_001177639.2 116 acC/acT 0 +DAG1 UCSF GRCh37 3 49548030 49548030 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 62 114 0 ENST00000308775.2:c.63G>A p.Leu21= p.L21= ENST00000308775 NM_001177639.2 21 ctG/ctA 0 +DAO UCSF GRCh37 12 109294270 109294270 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 80 163 0 ENST00000228476.3:c.1003G>A p.Glu335Lys p.E335K ENST00000228476 NM_001917.4 335 Gaa/Aaa 0 +DAPK1 UCSF GRCh37 9 90263709 90263709 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 65 168 0 ENST00000358077.5:c.1343C>T p.Ala448Val p.A448V ENST00000358077 NM_001288731.1 448 gCc/gTc 0 +DAXX UCSF GRCh37 6 33288940 33288940 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 24 55 0 ENST00000266000.6:c.612G>A p.Arg204= p.R204= ENST00000266000 204 cgG/cgA 0 +DAXX UCSF GRCh37 6 33287477 33287477 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 74 178 0 ENST00000266000.6:c.1620C>T p.Pro540= p.P540= ENST00000266000 540 ccC/ccT 0 +DCAF11 UCSF GRCh37 14 24592253 24592253 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 58 115 0 ENST00000446197.3:c.1473G>A p.Trp491Ter p.W491* ENST00000446197 NM_025230.4 491 tgG/tgA 0 +DCAF4 UCSF GRCh37 14 73422231 73422231 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 116 232 0 ENST00000358377.2:c.1006G>A p.Ala336Thr p.A336T ENST00000358377 NM_001163509.1 336 Gct/Act 0 +DCAF4L1 UCSF GRCh37 4 41984708 41984708 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 93 206 0 ENST00000333141.5:c.899G>A p.Arg300Lys p.R300K ENST00000333141 NM_001029955.3 300 aGg/aAg 0 +DCAF5 UCSF GRCh37 14 69589060 69589060 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 53 136 0 ENST00000341516.5:c.232G>A p.Val78Ile p.V78I ENST00000341516 NM_003861.2 78 Gtt/Att 0 +DCBLD2 UCSF GRCh37 3 98518407 98518407 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 210 118 333 0 ENST00000326840.6:c.2137G>A p.Gly713Arg p.G713R ENST00000326840 NM_080927.3 713 Gga/Aga 0 +DCC UCSF GRCh37 18 50923802 50923802 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 70 149 0 ENST00000442544.2:c.2813C>T p.Thr938Ile p.T938I ENST00000442544 NM_005215.3 938 aCc/aTc 0 +DCDC5 UCSF GRCh37 11 30946895 30946895 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 185 129 290 0 ENST00000339794.5:c.195G>A p.Lys65= p.K65= ENST00000339794 65 aaG/aaA 0 +DCHS2 UCSF GRCh37 4 155156392 155156392 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 54 137 0 ENST00000357232.4:c.8047G>A p.Asp2683Asn p.D2683N ENST00000357232 NM_017639.3 2683 Gac/Aac 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 16 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DCLK2 UCSF GRCh37 4 151114344 151114344 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 90 225 0 ENST00000296550.7:c.811C>T p.Pro271Ser p.P271S ENST00000296550 NM_001040260.3 271 Cca/Tca 0 +DCLK2 UCSF GRCh37 4 151023922 151023922 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 59 171 0 ENST00000296550.7:c.714C>T p.Asp238= p.D238= ENST00000296550 NM_001040260.3 238 gaC/gaT 0 +DCLRE1A UCSF GRCh37 10 115608882 115608882 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 223 179 387 0 ENST00000361384.2:c.1982C>T p.Ser661Phe p.S661F ENST00000361384 NM_014881.4 661 tCt/tTt 0 +DCTN4 UCSF GRCh37 5 150133040 150133040 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 35 72 0 ENST00000447998.2:c.385+1G>A p.X129_splice ENST00000447998 NM_016221.3 0 +DDX17 UCSF GRCh37 22 38881953 38881953 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 64 94 0 ENST00000403230.1:c.2177C>T p.Pro726Leu p.P726L ENST00000403230 726 cCt/cTt 0 +DDX24 UCSF GRCh37 14 94528656 94528656 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 171 132 236 0 ENST00000330836.5:c.1030C>T p.Leu344= p.L344= ENST00000330836 NM_020414.3 344 Ctg/Ttg 0 +DDX28 UCSF GRCh37 16 68056152 68056152 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 101 181 0 ENST00000332395.5:c.954C>T p.Asp318= p.D318= ENST00000332395 NM_018380.3 318 gaC/gaT 0 +DDX41 UCSF GRCh37 5 176941964 176941964 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 48 78 0 ENST00000507955.1:c.751C>T p.Pro251Ser p.P251S ENST00000507955 NM_016222.2 251 Ccc/Tcc 0 +DDX60 UCSF GRCh37 4 169206643 169206643 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 34 67 0 ENST00000393743.3:c.1346C>T p.Ser449Phe p.S449F ENST00000393743 NM_017631.5 449 tCc/tTc 0 +DDX60L UCSF GRCh37 4 169343778 169343778 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 67 116 0 ENST00000260184.7:c.2141G>A p.Gly714Glu p.G714E ENST00000260184 NM_001012967.1 714 gGa/gAa 0 +DEC1 UCSF GRCh37 9 118163567 118163567 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 64 147 0 ENST00000374016.1:c.183G>A p.Arg61= p.R61= ENST00000374016 NM_017418.2 61 agG/agA 0 +DEDD2 UCSF GRCh37 19 42703731 42703731 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 35 70 0 ENST00000595337.1:c.840G>A p.Leu280= p.L280= ENST00000595337 NM_001270614.1 280 ctG/ctA 0 +DEFA6 UCSF GRCh37 8 6783437 6783437 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 24 63 0 ENST00000297436.2:c.121C>T p.Gln41Ter p.Q41* ENST00000297436 NM_001926.3 41 Cag/Tag 0 +DEFB115 UCSF GRCh37 20 29845509 29845509 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 56 138 0 ENST00000400552.1:c.43C>T p.Leu15Phe p.L15F ENST00000400552 NM_001037730.1 15 Ctc/Ttc 0 +DENND3 UCSF GRCh37 8 142146891 142146891 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 22 0 ENST00000262585.2:c.145+1G>A p.X49_splice ENST00000262585 NM_014957.2 0 +DENND3 UCSF GRCh37 8 142165968 142165968 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 104 203 0 ENST00000262585.2:c.855G>A p.Leu285= p.L285= ENST00000262585 NM_014957.2 285 ctG/ctA 0 +DENND4B UCSF GRCh37 1 153915483 153915483 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 49 112 0 ENST00000361217.4:c.441C>T p.Tyr147= p.Y147= ENST00000361217 NM_014856.2 147 taC/taT 0 +DEPDC1B UCSF GRCh37 5 59943252 59943252 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 51 118 0 ENST00000265036.5:c.423G>A p.Glu141= p.E141= ENST00000265036 NM_018369.2 141 gaG/gaA 0 +DGKH UCSF GRCh37 13 42772728 42772728 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 69 164 0 ENST00000337343.4:c.2282C>T p.Ser761Phe p.S761F ENST00000337343 NM_178009.3 761 tCc/tTc 0 +DHRS3 UCSF GRCh37 1 12640563 12640563 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 48 104 0 ENST00000376223.2:c.327C>T p.Ala109= p.A109= ENST00000376223 NM_004753.4 109 gcC/gcT 0 +DHRS4 UCSF GRCh37 14 24429110 24429110 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 250 92 339 0 ENST00000313250.5:c.307-1G>A p.X103_splice ENST00000313250 NM_021004.2 0 +DHRS4L2 UCSF GRCh37 14 24464240 24464240 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 424 90 413 0 ENST00000335125.6:c.307-1G>A p.X103_splice ENST00000335125 NM_198083.3 0 +DHX16 UCSF GRCh37 6 30622538 30622538 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 83 135 0 ENST00000376442.3:c.2942C>T p.Pro981Leu p.P981L ENST00000376442 NM_001164239.1 981 cCa/cTa 0 +DHX34 UCSF GRCh37 19 47865856 47865856 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 27 57 0 ENST00000328771.4:c.1499G>A p.Cys500Tyr p.C500Y ENST00000328771 NM_014681.5 500 tGc/tAc 0 +DHX36 UCSF GRCh37 3 154032946 154032946 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 86 158 0 ENST00000496811.1:c.492C>T p.Asp164= p.D164= ENST00000496811 NM_020865.2 164 gaC/gaT 0 +DHX38 UCSF GRCh37 16 72134369 72134369 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 43 80 0 ENST00000268482.3:c.1151C>T p.Thr384Ile p.T384I ENST00000268482 NM_014003.3 384 aCc/aTc 0 +DHX9 UCSF GRCh37 1 182849668 182849668 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 69 138 0 ENST00000367549.3:c.2549C>T p.Pro850Leu p.P850L ENST00000367549 NM_001357.4 850 cCt/cTt 0 +DIABLO UCSF GRCh37 12 122693086 122693086 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 44 113 0 ENST00000443649.3:c.562C>T p.Gln188Ter p.Q188* ENST00000443649 NM_019887.5 188 Cag/Tag 0 +DIEXF UCSF GRCh37 1 210024658 210024658 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 78 144 0 ENST00000491415.2:c.2137G>A p.Ala713Thr p.A713T ENST00000491415 NM_014388.6 713 Gcc/Acc 0 +DIP2B UCSF GRCh37 12 51069194 51069194 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 67 142 0 ENST00000301180.5:c.879G>A p.Lys293= p.K293= ENST00000301180 NM_173602.2 293 aaG/aaA 0 +DISP1 UCSF GRCh37 1 223164090 223164090 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 148 71 231 0 ENST00000284476.6:c.663G>A p.Leu221= p.L221= ENST00000284476 NM_032890.3 221 ctG/ctA 0 +DIXDC1 UCSF GRCh37 11 111857613 111857613 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 76 182 0 ENST00000440460.2:c.1024C>T p.Leu342= p.L342= ENST00000440460 NM_001037954.3 342 Ctg/Ttg 0 +DLG5 UCSF GRCh37 10 79579141 79579141 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 26 66 0 ENST00000372391.2:c.3609G>A p.Arg1203= p.R1203= ENST00000372391 NM_004747.3 1203 agG/agA 0 +DLGAP2 UCSF GRCh37 8 1497055 1497055 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 4 19 0 ENST00000421627.2:c.196G>A p.Val66Met p.V66M ENST00000421627 NM_004745.4 66 Gtg/Atg 0 +DLGAP3 UCSF GRCh37 1 35369974 35369974 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 67 123 0 ENST00000235180.4:c.1011C>T p.Val337= p.V337= ENST00000235180 NM_001080418.1 337 gtC/gtT 0 +DLK2 UCSF GRCh37 6 43420863 43420863 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 37 62 0 ENST00000357338.3:c.151G>A p.Gly51Ser p.G51S ENST00000357338 NM_206539.1 51 Ggc/Agc 0 +DLL1 UCSF GRCh37 6 170597827 170597827 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 68 190 0 ENST00000366756.3:c.402C>T p.Asp134= p.D134= ENST00000366756 NM_005618.3 134 gaC/gaT 0 +DMAP1 UCSF GRCh37 1 44684045 44684045 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 104 193 0 ENST00000315913.5:c.456G>A p.Trp152Ter p.W152* ENST00000315913 152 tgG/tgA 0 +DMXL1 UCSF GRCh37 5 118470064 118470064 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 182 101 326 1 ENST00000311085.8:c.2356C>T p.Leu786Phe p.L786F ENST00000311085 NM_005509.4 786 Ctt/Ttt 0 +DNAAF1 UCSF GRCh37 16 84188229 84188229 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 49 159 0 ENST00000378553.5:c.400C>T p.Leu134Phe p.L134F ENST00000378553 NM_178452.4 134 Ctc/Ttc 0 +DNAH14 UCSF GRCh37 1 225334902 225334902 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 102 197 0 ENST00000445597.2:c.3537+2572G>A *1179* ENST00000445597 0 +DNAH14 UCSF GRCh37 1 225577523 225577523 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 173 125 258 0 ENST00000445597.2:c.9948C>T p.Phe3316= p.F3316= ENST00000445597 3316 ttC/ttT 0 +DNAH17 UCSF GRCh37 17 76525584 76525584 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 98 191 0 ENST00000389840.5:c.3477G>A p.Glu1159= p.E1159= ENST00000389840 1159 gaG/gaA 0 +DNAH2 UCSF GRCh37 17 7736727 7736727 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 43 139 0 ENST00000389173.2:c.13160C>T p.Pro4387Leu p.P4387L ENST00000389173 NM_020877.2 4387 cCc/cTc 0 +DNAH2 UCSF GRCh37 17 7637966 7637966 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 70 159 0 ENST00000389173.2:c.918C>T p.Ile306= p.I306= ENST00000389173 NM_020877.2 306 atC/atT 0 +DNAH3 UCSF GRCh37 16 21080757 21080757 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 86 221 0 ENST00000261383.3:c.3360G>A p.Trp1120Ter p.W1120* ENST00000261383 NM_017539.1 1120 tgG/tgA 0 +DNAH7 UCSF GRCh37 2 196728926 196728926 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 71 140 0 ENST00000312428.6:c.7453C>T p.Arg2485Cys p.R2485C ENST00000312428 NM_018897.2 2485 Cgt/Tgt 0 +DNAH8 UCSF GRCh37 6 38690880 38690880 + upstream_gene_variant 5'Flank SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 188 157 297 0 ENST00000359357 0 +DNAH9 UCSF GRCh37 17 11835454 11835454 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 82 210 0 ENST00000262442.4:c.12229C>T p.Pro4077Ser p.P4077S ENST00000262442 NM_001372.3 4077 Ccc/Tcc 0 +DNAH9 UCSF GRCh37 17 11865278 11865278 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 125 96 226 0 ENST00000262442.4:c.12938C>T p.Ser4313Phe p.S4313F ENST00000262442 NM_001372.3 4313 tCc/tTc 0 +DNAH9 UCSF GRCh37 17 11523033 11523033 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 157 116 237 0 ENST00000262442.4:c.1285G>A p.Asp429Asn p.D429N ENST00000262442 NM_001372.3 429 Gat/Aat 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 124 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DNAI2 UCSF GRCh37 17 72295924 72295924 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 41 89 0 ENST00000311014.6:c.792C>T p.Asp264= p.D264= ENST00000311014 264 gaC/gaT 0 +DNAJC1 UCSF GRCh37 10 22171240 22171240 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 40 95 1 ENST00000376980.3:c.949G>A p.Glu317Lys p.E317K ENST00000376980 NM_022365.3 317 Gaa/Aaa 0 +DNAJC2 UCSF GRCh37 7 102957397 102957397 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 131 89 211 0 ENST00000379263.3:c.1307C>T p.Ala436Val p.A436V ENST00000379263 NM_014377.1 436 gCa/gTa 0 +DNASE1L1 UCSF GRCh37 X 153633810 153633810 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 39 24 0 ENST00000014935.3:c.100G>A p.Val34Met p.V34M ENST00000014935 34 Gtg/Atg 0 +DNHD1 UCSF GRCh37 11 6588286 6588286 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 98 207 0 ENST00000254579.6:c.11547C>T p.Pro3849= p.P3849= ENST00000254579 NM_144666.2 3849 ccC/ccT 0 +DNM2 UCSF GRCh37 19 10916604 10916604 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 43 111 0 ENST00000355667.6:c.1506G>A p.Arg502= p.R502= ENST00000355667 NM_001005360.2 502 agG/agA 0 +DOCK1 UCSF GRCh37 10 129172097 129172097 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 57 169 0 ENST00000280333.6:c.3422G>A p.Gly1141Glu p.G1141E ENST00000280333 NM_001380.3 1141 gGa/gAa 0 +DOCK10 UCSF GRCh37 2 225714287 225714287 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 50 0 ENST00000258390.7:c.2172C>T p.Leu724= p.L724= ENST00000258390 NM_014689.2 724 ctC/ctT 0 +DOCK3 UCSF GRCh37 3 51308422 51308422 + synonymous_variant Silent SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 164 137 259 0 ENST00000266037.9:c.2532C>T p.Arg844= p.R844= ENST00000266037 NM_004947.4 844 cgC/cgT 0 +DOCK3 UCSF GRCh37 3 51264836 51264836 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 168 133 285 0 ENST00000266037.9:c.1500C>T p.Phe500= p.F500= ENST00000266037 NM_004947.4 500 ttC/ttT 0 +DOCK7 UCSF GRCh37 1 63027353 63027353 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 107 65 161 0 ENST00000340370.5:c.2134T>C p.Trp712Arg p.W712R ENST00000340370 NM_033407.3 712 Tgg/Cgg 0 +DOK2 UCSF GRCh37 8 21766883 21766883 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 61 134 0 ENST00000276420.4:c.1178C>T p.Ala393Val p.A393V ENST00000276420 NM_003974.2 393 gCt/gTt 0 +DOM3Z UCSF GRCh37 6 31939281 31939281 + missense_variant Missense_Mutation SNP G G A snp132_rs115027323 P18_Rec Untested WXS Illumina HiSeq 65 59 98 0 ENST00000337523.5:c.172C>T p.Arg58Cys p.R58C ENST00000337523 NM_005510.3 58 Cgc/Tgc 0 +DPEP3 UCSF GRCh37 16 68014163 68014163 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 18 30 0 ENST00000268793.4:c.196G>A p.Gly66Ser p.G66S ENST00000268793 NM_022357.3 66 Ggc/Agc 0 +DPF1 UCSF GRCh37 19 38713026 38713026 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 63 130 0 ENST00000420980.2:c.350C>T p.Pro117Leu p.P117L ENST00000420980 NM_004647.2 117 cCc/cTc 0 +DPH2 UCSF GRCh37 1 44436675 44436675 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 11 15 0 ENST00000255108.3:c.298G>A p.Ala100Thr p.A100T ENST00000255108 NM_001384.4 100 Gct/Act 0 +DPH2 UCSF GRCh37 1 44437200 44437200 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 77 149 0 ENST00000255108.3:c.626G>A p.Arg209Lys p.R209K ENST00000255108 NM_001384.4 209 aGg/aAg 0 +DPY19L3 UCSF GRCh37 19 32971452 32971452 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 42 75 0 ENST00000342179.5:c.1978G>A p.Ala660Thr p.A660T ENST00000342179 NM_207325.2 660 Gcc/Acc 0 +DPY19L4 UCSF GRCh37 8 95793303 95793310 + splice_acceptor_variant,intron_variant Splice_Site INS GCATTTTA GCATTTTA TTCCTTTTT NOVEL P18_Rec Untested WXS Illumina HiSeq 10 0 ENST00000414645.2:c.1633-9_1633-2delinsTTCCTTTTT p.X545_splice ENST00000414645 NM_181787.2 0 +DPYD UCSF GRCh37 1 97564070 97564070 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 93 247 0 ENST00000370192.3:c.2741C>T p.Pro914Leu p.P914L ENST00000370192 NM_000110.3 914 cCc/cTc 0 +DPYSL2 UCSF GRCh37 8 26485411 26485411 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 19 50 0 ENST00000311151.5:c.645G>A p.Leu215= p.L215= ENST00000311151 NM_001386.5 215 ctG/ctA 0 +DSCAML1 UCSF GRCh37 11 117387190 117387190 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 21 54 0 ENST00000321322.6:c.1955C>T p.Ala652Val p.A652V ENST00000321322 NM_020693.2 652 gCc/gTc 0 +DSCR4 UCSF GRCh37 21 39492435 39492435 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 46 116 0 ENST00000328264.3:c.196C>T p.Pro66Ser p.P66S ENST00000328264 NM_005867.2 66 Cct/Tct 0 +DSP UCSF GRCh37 6 7582925 7582925 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 122 86 172 0 ENST00000379802.3:c.5430G>A p.Gln1810= p.Q1810= ENST00000379802 NM_004415.2 1810 caG/caA 0 +DSPP UCSF GRCh37 4 88534257 88534257 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 56 166 1 ENST00000282478.7:c.919C>A p.Pro307Thr p.P307T ENST00000282478 307 Cct/Act 0 +DST UCSF GRCh37 6 56330989 56330989 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 86 210 0 ENST00000244364.6:c.14705G>A p.Gly4902Glu p.G4902E ENST00000244364 NM_015548.4 4902 gGa/gAa 0 +DST UCSF GRCh37 6 56422302 56422302 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 71 170 0 ENST00000244364.6:c.6586G>A p.Glu2196Lys p.E2196K ENST00000244364 NM_015548.4 2196 Gaa/Aaa 0 +DST UCSF GRCh37 6 56433267 56433267 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 191 128 295 0 ENST00000244364.6:c.6136G>A p.Gly2046Ser p.G2046S ENST00000244364 NM_015548.4 2046 Ggt/Agt 0 +DUOX2 UCSF GRCh37 15 45393011 45393011 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 58 119 0 ENST00000603300.1:c.2947C>T p.Pro983Ser p.P983S ENST00000603300 NM_014080.4 983 Cct/Tct 0 +DUOX2 UCSF GRCh37 15 45401098 45401098 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 67 170 0 ENST00000603300.1:c.1287C>T p.Ser429= p.S429= ENST00000603300 NM_014080.4 429 agC/agT 0 +DUS1L UCSF GRCh37 17 80022025 80022025 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 20 46 0 ENST00000306796.5:c.323G>A p.Cys108Tyr p.C108Y ENST00000306796 NM_022156.4 108 tGc/tAc 0 +DUSP11 UCSF GRCh37 2 74005494 74005494 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 54 127 0 ENST00000272444.3:c.252C>T p.Asp84= p.D84= ENST00000272444 NM_003584.2 84 gaC/gaT 0 +DUSP22 UCSF GRCh37 6 348153 348153 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 225 73 284 0 ENST00000344450.5:c.314C>T p.Thr105Ile p.T105I ENST00000344450 NM_020185.3 105 aCc/aTc 0 +DUSP22 UCSF GRCh37 6 345859 345859 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 27 113 0 ENST00000344450.5:c.194G>A p.Arg65Lys p.R65K ENST00000344450 NM_020185.3 65 aGa/aAa 0 +DVL2 UCSF GRCh37 17 7133431 7133431 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 63 153 0 ENST00000005340.5:c.454G>A p.Glu152Lys p.E152K ENST00000005340 NM_004422.2 152 Gaa/Aaa 0 +DYNC1H1 UCSF GRCh37 14 102446879 102446879 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 41 88 0 ENST00000360184.4:c.953C>T p.Thr318Ile p.T318I ENST00000360184 NM_001376.4 318 aCt/aTt 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 75 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +DZIP3 UCSF GRCh37 3 108403174 108403174 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 195 146 283 0 ENST00000361582.3:c.2995C>T p.Pro999Ser p.P999S ENST00000361582 NM_014648.3 999 Cct/Tct 0 +E2F3 UCSF GRCh37 6 20483110 20483110 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 65 163 0 ENST00000346618.3:c.843C>T p.Thr281= p.T281= ENST00000346618 NM_001949.4 281 acC/acT 0 +E2F8 UCSF GRCh37 11 19259421 19259421 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 176 113 256 0 ENST00000250024.4:c.274G>A p.Glu92Lys p.E92K ENST00000250024 NM_024680.3 92 Gag/Aag 0 +E4F1 UCSF GRCh37 16 2282801 2282801 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 45 99 0 ENST00000301727.4:c.775G>A p.Glu259Lys p.E259K ENST00000301727 NM_004424.3 259 Gag/Aag 0 +EBF3 UCSF GRCh37 10 131755587 131755587 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 77 156 0 ENST00000355311.5:c.489G>A p.Arg163= p.R163= ENST00000355311 163 cgG/cgA 0 +ECD UCSF GRCh37 10 74923685 74923685 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 83 175 0 ENST00000372979.4:c.11C>T p.Thr4Ile p.T4I ENST00000372979 NM_007265.2 4 aCc/aTc 0 +ECE2 UCSF GRCh37 3 184009200 184009200 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 29 81 0 ENST00000402825.3:c.2448C>T p.His816= p.H816= ENST00000402825 NM_014693.3 816 caC/caT 0 +ECEL1 UCSF GRCh37 2 233346327 233346327 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 14 38 0 ENST00000304546.1:c.1878C>T p.Asp626= p.D626= ENST00000304546 NM_004826.2 626 gaC/gaT 0 +ECT2L UCSF GRCh37 6 139186154 139186154 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 43 133 0 ENST00000367682.2:c.1313C>T p.Ser438Phe p.S438F ENST00000367682 NM_001077706.2 438 tCc/tTc 0 +EDC4 UCSF GRCh37 16 67914460 67914460 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 85 181 0 ENST00000358933.5:c.2098G>A p.Val700Met p.V700M ENST00000358933 NM_014329.4 700 Gtg/Atg 0 +EDDM3B UCSF GRCh37 14 21238360 21238360 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 65 129 0 ENST00000326783.3:c.51C>T p.Ile17= p.I17= ENST00000326783 NM_022360.4 17 atC/atT 0 +EEF1G UCSF GRCh37 11 62339367 62339367 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 43 82 0 ENST00000329251.4:c.178G>A p.Ala60Thr p.A60T ENST00000329251 NM_001404.4 60 Gca/Aca 0 +EEFSEC UCSF GRCh37 3 128060344 128060344 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 84 68 139 0 ENST00000254730.6:c.1055G>A p.Ser352Asn p.S352N ENST00000254730 NM_021937.3 352 aGt/aAt 0 +EFCAB4B UCSF GRCh37 12 3757770 3757770 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 44 29 76 0 ENST00000252322.1:c.1056C>T p.Tyr352= p.Y352= ENST00000252322 NM_032680.3 352 taC/taT 0 +EFNA2 UCSF GRCh37 19 1295590 1295590 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 8 26 0 ENST00000215368.2:c.187G>A p.Val63Met p.V63M ENST00000215368 NM_001405.3 63 Gtg/Atg 0 +EFNA3 UCSF GRCh37 1 155058671 155058671 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 13 37 0 ENST00000368408.3:c.576C>T p.Ile192= p.I192= ENST00000368408 NM_004952.4 192 atC/atT 0 +EFS UCSF GRCh37 14 23829833 23829833 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 28 70 0 ENST00000216733.3:c.228C>T p.Leu76= p.L76= ENST00000216733 NM_005864.3 76 ctC/ctT 0 +EGFR UCSF GRCh37 7 55242501 55242501 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 56 144 0 ENST00000275493.2:c.2271G>A p.Lys757= p.K757= ENST00000275493 NM_005228.3 757 aaG/aaA 0 +EGR2 UCSF GRCh37 10 64574204 64574204 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 49 111 0 ENST00000242480.3:c.194C>T p.Thr65Ile p.T65I ENST00000242480 NM_001136177.1 65 aCt/aTt 0 +EHD2 UCSF GRCh37 19 48220001 48220001 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 19 51 0 ENST00000263277.3:c.132C>T p.Ala44= p.A44= ENST00000263277 NM_014601.3 44 gcC/gcT 0 +EHMT2 UCSF GRCh37 6 31854826 31854826 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 37 74 0 ENST00000375537.4:c.2064C>T p.Pro688= p.P688= ENST00000375537 NM_006709.3 688 ccC/ccT 0 +EHMT2 UCSF GRCh37 6 31864507 31864507 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 55 146 0 ENST00000375537.4:c.204C>T p.Ala68= p.A68= ENST00000375537 NM_006709.3 68 gcC/gcT 0 +EIF2AK1 UCSF GRCh37 7 6064421 6064421 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 84 178 0 ENST00000199389.6:c.1776C>T p.Thr592= p.T592= ENST00000199389 NM_001134335.1 592 acC/acT 0 +EIF2C1 UCSF GRCh37 1 36385140 36385140 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 15 46 0 ENST00000373204.4:c.2506G>A p.Asp836Asn p.D836N ENST00000373204 NM_012199.2 836 Gac/Aac 0 +EIF2C2 UCSF GRCh37 8 141568663 141568663 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 49 114 0 ENST00000220592.5:c.799G>A p.Val267Met p.V267M ENST00000220592 NM_012154.3 267 Gtg/Atg 0 +EIF3A UCSF GRCh37 10 120833414 120833414 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 63 127 0 ENST00000369144.3:c.85G>A p.Asp29Asn p.D29N ENST00000369144 NM_003750.2 29 Gat/Aat 0 +EIF5B UCSF GRCh37 2 99984995 99984995 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 43 115 0 ENST00000289371.6:c.1328G>A p.Arg443Lys p.R443K ENST00000289371 NM_015904.3 443 aGg/aAg 0 +ELF1 UCSF GRCh37 13 41515250 41515250 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 134 270 0 ENST00000239882.3:c.1063C>T p.Pro355Ser p.P355S ENST00000239882 NM_172373.3 355 Ccc/Tcc 0 +ELF5 UCSF GRCh37 11 34502512 34502512 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 48 127 0 ENST00000312319.2:c.508C>T p.Leu170Phe p.L170F ENST00000312319 NM_001243081.1 170 Ctc/Ttc 0 +ELP4 UCSF GRCh37 11 31531461 31531461 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 30 71 0 ENST00000350638.5:c.130C>T p.Pro44Ser p.P44S ENST00000350638 NM_019040.3 44 Cct/Tct 0 +ELP4 UCSF GRCh37 11 31561313 31561313 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 97 192 0 ENST00000350638.5:c.364C>T p.Pro122Ser p.P122S ENST00000350638 NM_019040.3 122 Cct/Tct 0 +EMID1 UCSF GRCh37 22 29654839 29654839 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 26 69 0 ENST00000334018.6:c.1238G>A p.Gly413Asp p.G413D ENST00000334018 NM_001267895.1 413 gGc/gAc 0 +EML4 UCSF GRCh37 2 42513493 42513493 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 125 195 0 ENST00000318522.5:c.1096G>A p.Val366Ile p.V366I ENST00000318522 NM_019063.3 366 Gta/Ata 0 +ENC1 UCSF GRCh37 5 73932029 73932029 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 72 159 0 ENST00000302351.4:c.282C>T p.His94= p.H94= ENST00000302351 NM_003633.3 94 caC/caT 0 +ENOSF1 UCSF GRCh37 18 677400 677400 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 60 156 0 ENST00000251101.7:c.1093G>A p.Val365Met p.V365M ENST00000251101 NM_017512.5 365 Gtg/Atg 0 +ENPP2 UCSF GRCh37 8 120575108 120575108 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 57 170 0 ENST00000075322.6:c.2410G>A p.Glu804Lys p.E804K ENST00000075322 NM_001040092.2 804 Gag/Aag 0 +ENPP3 UCSF GRCh37 6 131962671 131962671 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 51 86 0 ENST00000357639.3:c.154+1G>A p.X52_splice ENST00000357639 NM_005021.3 0 +EP300 UCSF GRCh37 22 41554450 41554450 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 45 93 0 ENST00000263253.7:c.3536G>A p.Gly1179Asp p.G1179D ENST00000263253 NM_001429.3 1179 gGc/gAc 0 +EP400 UCSF GRCh37 12 132445312 132445312 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 35 73 0 ENST00000389561.2:c.148G>A p.Ala50Thr p.A50T ENST00000389561 NM_015409.4 50 Gca/Aca 0 +EPB41L1 UCSF GRCh37 20 34802304 34802304 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 29 51 0 ENST00000338074.2:c.2210G>A p.Gly737Glu p.G737E ENST00000338074 NM_012156.2 737 gGg/gAg 0 +EPB42 UCSF GRCh37 15 43489632 43489632 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 49 120 0 ENST00000441366.2:c.1944G>A p.Met648Ile p.M648I ENST00000441366 NM_001114134.1 648 atG/atA 0 +EPG5 UCSF GRCh37 18 43460180 43460180 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 48 88 0 ENST00000282041.5:c.5527G>A p.Glu1843Lys p.E1843K ENST00000282041 NM_020964.2 1843 Gag/Aag 0 +EPHA3 UCSF GRCh37 3 89259579 89259579 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 191 130 282 0 ENST00000336596.2:c.723G>A p.Arg241= p.R241= ENST00000336596 NM_005233.5 241 agG/agA 0 +EPHB2 UCSF GRCh37 1 23233224 23233224 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 34 36 83 0 ENST00000400191.3:c.1910G>A p.Ser637Asn p.S637N ENST00000400191 NM_004442.6 637 aGt/aAt 0 +EPHB2 UCSF GRCh37 1 23236953 23236953 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 61 128 0 ENST00000400191.3:c.2581G>A p.Asp861Asn p.D861N ENST00000400191 NM_004442.6 861 Gac/Aac 0 +EPHB4 UCSF GRCh37 7 100405188 100405188 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 43 138 0 ENST00000358173.3:c.2133G>A p.Gln711= p.Q711= ENST00000358173 NM_004444.4 711 caG/caA 0 +EPM2AIP1 UCSF GRCh37 3 37033760 37033760 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 107 184 0 ENST00000322716.5:c.809C>T p.Pro270Leu p.P270L ENST00000322716 NM_014805.3 270 cCc/cTc 0 +EPPK1 UCSF GRCh37 8 144941870 144941870 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 91 194 1 ENST00000525985.1:c.5552G>A p.Arg1851Lys p.R1851K ENST00000525985 NM_031308.2 1851 aGa/aAa 0 +EPPK1 UCSF GRCh37 8 144945283 144945283 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 65 146 0 ENST00000525985.1:c.2139G>A p.Arg713= p.R713= ENST00000525985 NM_031308.2 713 cgG/cgA 0 +EPX UCSF GRCh37 17 56274611 56274611 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 43 97 0 ENST00000225371.5:c.1113C>T p.Phe371= p.F371= ENST00000225371 NM_000502.4 371 ttC/ttT 0 +ERAP1 UCSF GRCh37 5 96139106 96139106 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 69 147 0 ENST00000443439.2:c.524G>A p.Arg175Lys p.R175K ENST00000443439 NM_001040458.1 175 aGg/aAg 0 +ERBB2IP UCSF GRCh37 5 65350661 65350661 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 51 156 0 ENST00000284037.5:c.3515G>A p.Arg1172Lys p.R1172K ENST00000284037 NM_001253697.1 1172 aGa/aAa 0 +ERBB4 UCSF GRCh37 2 212483992 212483992 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 39 98 0 ENST00000342788.4:c.2211G>A p.Trp737Ter p.W737* ENST00000342788 NM_005235.2 737 tgG/tgA 0 +ERP27 UCSF GRCh37 12 15070178 15070178 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 85 198 0 ENST00000266397.2:c.510G>A p.Lys170= p.K170= ENST00000266397 NM_152321.2 170 aaG/aaA 0 +ESRRB UCSF GRCh37 14 76966402 76966402 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 63 139 0 ENST00000380887.2:c.1493G>A p.Gly498Glu p.G498E ENST00000380887 498 gGa/gAa 0 +ESRRG UCSF GRCh37 1 216692502 216692502 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 45 152 0 ENST00000408911.3:c.1124C>T p.Ala375Val p.A375V ENST00000408911 NM_001438.3 375 gCt/gTt 0 +ETFB UCSF GRCh37 19 51869553 51869553 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 16 26 0 ENST00000309244.4:c.28G>A p.Val10Ile p.V10I ENST00000309244 NM_001985.2 10 Gtc/Atc 0 +ETFDH UCSF GRCh37 4 159627470 159627470 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 73 156 0 ENST00000511912.1:c.1415G>A p.Gly472Glu p.G472E ENST00000511912 NM_004453.2 472 gGa/gAa 0 +ETS1 UCSF GRCh37 11 128359262 128359262 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 174 153 313 0 ENST00000319397.6:c.326G>A p.Gly109Asp p.G109D ENST00000319397 NM_005238.3 109 gGt/gAt 0 +ETV3 UCSF GRCh37 1 157095543 157095543 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 31 46 0 ENST00000368192.4:c.629C>T p.Ser210Phe p.S210F ENST00000368192 NM_001145312.1 210 tCc/tTc 0 +EXOC6 UCSF GRCh37 10 94700484 94700484 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 27 88 0 ENST00000260762.6:c.1213G>A p.Gly405Ser p.G405S ENST00000260762 NM_019053.4 405 Ggt/Agt 0 +EXOSC2 UCSF GRCh37 9 133573605 133573605 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 54 89 0 ENST00000372358.5:c.327G>A p.Leu109= p.L109= ENST00000372358 109 ctG/ctA 0 +EXPH5 UCSF GRCh37 11 108382821 108382821 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 75 222 0 ENST00000265843.4:c.3413G>A p.Gly1138Glu p.G1138E ENST00000265843 NM_015065.2 1138 gGa/gAa 0 +EYA3 UCSF GRCh37 1 28362189 28362189 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 88 209 0 ENST00000373871.3:c.227C>T p.Pro76Leu p.P76L ENST00000373871 76 cCt/cTt 0 +EZR UCSF GRCh37 6 159205752 159205752 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 32 91 0 ENST00000337147.7:c.475G>A p.Asp159Asn p.D159N ENST00000337147 NM_003379.4 159 Gac/Aac 0 +F2RL3 UCSF GRCh37 19 17000773 17000773 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 6 19 0 ENST00000248076.3:c.499C>T p.Leu167= p.L167= ENST00000248076 NM_003950.2 167 Ctg/Ttg 0 +FAF1 UCSF GRCh37 1 51253837 51253837 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 56 168 0 ENST00000396153.2:c.202C>T p.Pro68Ser p.P68S ENST00000396153 NM_007051.2 68 Cca/Tca 0 +FAF2 UCSF GRCh37 5 175913454 175913454 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 70 145 0 ENST00000261942.6:c.231G>A p.Arg77= p.R77= ENST00000261942 NM_014613.2 77 agG/agA 0 +FAM105A UCSF GRCh37 5 14609106 14609106 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0011 P18_Rec Untested WXS Illumina HiSeq 208 135 280 0 ENST00000274217.3:c.877G>A p.Asp293Asn p.D293N ENST00000274217 NM_019018.2 293 Gac/Aac 0 +FAM107B UCSF GRCh37 10 14816616 14816616 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 71 149 0 ENST00000181796.2:c.47C>T p.Ser16Phe p.S16F ENST00000181796 NM_031453.2 16 tCt/tTt 0 +FAM109B UCSF GRCh37 22 42474031 42474031 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 9 20 0 ENST00000321753.3:c.734G>A p.Arg245Lys p.R245K ENST00000321753 NM_001002034.2 245 aGg/aAg 0 +FAM110B UCSF GRCh37 8 59059803 59059803 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 60 112 0 ENST00000361488.3:c.1014G>A p.Val338= p.V338= ENST00000361488 NM_147189.2 338 gtG/gtA 0 +FAM116A UCSF GRCh37 3 57614579 57614579 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 84 204 0 ENST00000311128.5:c.1654G>A p.Val552Ile p.V552I ENST00000311128 NM_152678.2 552 Gta/Ata 0 +FAM123C UCSF GRCh37 2 131519926 131519926 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 12 28 0 ENST00000321420.4:c.281C>T p.Thr94Ile p.T94I ENST00000321420 94 aCt/aTt 0 +FAM129C UCSF GRCh37 19 17653039 17653039 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 82 145 1 ENST00000335393.4:c.1358C>T p.Ala453Val p.A453V ENST00000335393 NM_173544.4 453 gCa/gTa 0 +FAM131C UCSF GRCh37 1 16386429 16386429 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 6 36 0 ENST00000375662.4:c.386C>T p.Ser129Phe p.S129F ENST00000375662 NM_182623.2 129 tCc/tTc 0 +FAM13B UCSF GRCh37 5 137278595 137278595 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 111 209 0 ENST00000033079.3:c.2491C>T p.Leu831Phe p.L831F ENST00000033079 NM_016603.2 831 Ctc/Ttc 0 +FAM149A UCSF GRCh37 4 187078868 187078868 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 72 113 0 ENST00000356371.5:c.1597C>T p.Pro533Ser p.P533S ENST00000356371 533 Ccc/Tcc 0 +FAM149B1 UCSF GRCh37 10 74995047 74995047 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 142 105 226 0 ENST00000242505.6:c.1573C>T p.Pro525Ser p.P525S ENST00000242505 NM_173348.1 525 Ccc/Tcc 0 +FAM154B UCSF GRCh37 15 82574934 82574934 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 69 170 0 ENST00000339465.5:c.728G>A p.Gly243Asp p.G243D ENST00000339465 NM_001008226.1 243 gGt/gAt 0 +FAM160A2 UCSF GRCh37 11 6245656 6245656 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 50 137 0 ENST00000449352.2:c.91G>A p.Ala31Thr p.A31T ENST00000449352 31 Gct/Act 0 +FAM161B UCSF GRCh37 14 74411536 74411536 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 21 43 0 ENST00000286544.3:c.616C>A p.Pro206Thr p.P206T ENST00000286544 NM_152445.2 206 Ccc/Acc 0 +FAM163A UCSF GRCh37 1 179783116 179783116 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 32 83 0 ENST00000341785.4:c.296C>T p.Ser99Phe p.S99F ENST00000341785 NM_173509.2 99 tCc/tTc 0 +FAM171B UCSF GRCh37 2 187605111 187605111 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 68 159 1 ENST00000304698.5:c.395G>A p.Gly132Glu p.G132E ENST00000304698 NM_177454.3 132 gGa/gAa 0 +FAM171B UCSF GRCh37 2 187627152 187627152 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 76 160 0 ENST00000304698.5:c.2083G>A p.Gly695Ser p.G695S ENST00000304698 NM_177454.3 695 Ggc/Agc 0 +FAM178B UCSF GRCh37 2 97637810 97637810 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 16 0 ENST00000417561.3:c.836C>T p.Ala279Val p.A279V ENST00000417561 279 gCc/gTc 0 +FAM180B UCSF GRCh37 11 47609803 47609803 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 34 83 0 ENST00000356737.2:c.492C>T p.Leu164= p.L164= ENST00000356737 164 ctC/ctT 0 +FAM184B UCSF GRCh37 4 17654527 17654527 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 11 20 0 ENST00000265018.3:c.2117C>T p.Ala706Val p.A706V ENST00000265018 NM_015688.1 706 gCc/gTc 0 +FAM188A UCSF GRCh37 10 15902243 15902243 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 19 28 0 ENST00000277632.3:c.56C>T p.Pro19Leu p.P19L ENST00000277632 NM_024948.2 19 cCc/cTc 0 +FAM194B UCSF GRCh37 13 46171026 46171026 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 95 220 0 ENST00000298738.2:c.115G>A p.Asp39Asn p.D39N ENST00000298738 NM_182542.2 39 Gat/Aat 0 +FAM203A UCSF GRCh37 8 145193675 145193675 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 29 88 0 ENST00000347708.4:c.752C>T p.Pro251Leu p.P251L ENST00000347708 NM_016458.2 251 cCc/cTc 0 +FAM208B UCSF GRCh37 10 5788719 5788719 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 358 148 299 0 ENST00000328090.5:c.3335C>T p.Ser1112Phe p.S1112F ENST00000328090 NM_017782.4 1112 tCt/tTt 0 +FAM20A UCSF GRCh37 17 66537057 66537057 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 18 20 34 0 ENST00000592554.1:c.1152C>T p.Ile384= p.I384= ENST00000592554 NM_001243746.1 384 atC/atT 0 +FAM32A UCSF GRCh37 19 16296498 16296498 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 11 24 0 ENST00000263384.7:c.138G>A p.Lys46= p.K46= ENST00000263384 NM_014077.2 46 aaG/aaA 0 +FAM40A UCSF GRCh37 1 110590402 110590402 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 8 13 0 ENST00000369795.3:c.1572C>T p.Leu524= p.L524= ENST00000369795 NM_033088.3 524 ctC/ctT 0 +FAM47E UCSF GRCh37 4 77199326 77199326 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 59 125 0 ENST00000424749.2:c.975G>A p.Glu325= p.E325= ENST00000424749 NM_001136570.2 325 gaG/gaA 0 +FAM65A UCSF GRCh37 16 67572917 67572917 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 35 103 0 ENST00000379312.3:c.294G>A p.Gln98= p.Q98= ENST00000379312 NM_001193522.1 98 caG/caA 0 +FAM71B UCSF GRCh37 5 156590120 156590120 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 46 101 0 ENST00000302938.4:c.1156G>A p.Ala386Thr p.A386T ENST00000302938 NM_130899.2 386 Gca/Aca 0 +FAM71F1 UCSF GRCh37 7 128355653 128355653 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 73 128 0 ENST00000315184.5:c.158G>A p.Gly53Asp p.G53D ENST00000315184 NM_032599.2 53 gGt/gAt 0 +FAM73B UCSF GRCh37 9 131825526 131825526 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 13 51 0 ENST00000358369.4:c.1014G>A p.Thr338= p.T338= ENST00000358369 NM_032809.2 338 acG/acA 0 +FAM83G UCSF GRCh37 17 18891670 18891670 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 64 158 0 ENST00000345041.4:c.580G>A p.Asp194Asn p.D194N ENST00000345041 194 Gac/Aac 0 +FAM84A UCSF GRCh37 2 14774968 14774968 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 28 46 0 ENST00000295092.2:c.865G>A p.Asp289Asn p.D289N ENST00000295092 NM_145175.2 289 Gac/Aac 0 +FANCD2 UCSF GRCh37 3 10128823 10128823 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 201 147 313 0 ENST00000383807.1:c.3341G>A p.Ser1114Asn p.S1114N ENST00000383807 NM_001018115.1 1114 aGc/aAc 0 +FANCM UCSF GRCh37 14 45636326 45636326 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 88 200 0 ENST00000267430.5:c.1962G>A p.Arg654= p.R654= ENST00000267430 NM_020937.2 654 cgG/cgA 0 +FARP1 UCSF GRCh37 13 99047730 99047730 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 37 101 0 ENST00000319562.6:c.1414G>A p.Gly472Ser p.G472S ENST00000319562 NM_005766.2 472 Ggc/Agc 0 +FARSB UCSF GRCh37 2 223464748 223464748 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 118 210 0 ENST00000281828.6:c.1517C>T p.Pro506Leu p.P506L ENST00000281828 NM_005687.3 506 cCt/cTt 0 +FASN UCSF GRCh37 17 80045130 80045130 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 5 26 0 ENST00000306749.2:c.3224-1G>A p.X1075_splice ENST00000306749 NM_004104.4 0 +FAT1 UCSF GRCh37 4 187558026 187558026 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 219 182 348 0 ENST00000441802.2:c.3685G>A p.Ala1229Thr p.A1229T ENST00000441802 NM_005245.3 1229 Gca/Aca 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 118 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FAT3 UCSF GRCh37 11 92539561 92539561 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 89 197 0 ENST00000298047.6:c.9127C>T p.Pro3043Ser p.P3043S ENST00000298047 3043 Cca/Tca 0 +FAT3 UCSF GRCh37 11 92592401 92592401 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 167 97 211 0 ENST00000298047.6:c.11571G>A p.Glu3857= p.E3857= ENST00000298047 3857 gaG/gaA 0 +FAT4 UCSF GRCh37 4 126241968 126241968 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 93 210 0 ENST00000394329.3:c.4402C>T p.His1468Tyr p.H1468Y ENST00000394329 NM_024582.4 1468 Cac/Tac 0 +FAT4 UCSF GRCh37 4 126239253 126239253 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 61 162 0 ENST00000394329.3:c.1687G>A p.Val563Met p.V563M ENST00000394329 NM_024582.4 563 Gtg/Atg 0 +FAT4 UCSF GRCh37 4 126411568 126411568 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 93 185 0 ENST00000394329.3:c.13591G>A p.Gly4531Arg p.G4531R ENST00000394329 NM_024582.4 4531 Ggg/Agg 0 +FBN2 UCSF GRCh37 5 127674694 127674694 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 79 176 0 ENST00000262464.4:c.3403C>T p.Pro1135Ser p.P1135S ENST00000262464 NM_001999.3 1135 Ccg/Tcg 0 +FBN3 UCSF GRCh37 19 8131101 8131101 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 27 46 0 ENST00000270509.2:c.8132G>A p.Gly2711Asp p.G2711D ENST00000270509 NM_032447.3 2711 gGc/gAc 0 +FBN3 UCSF GRCh37 19 8171033 8171033 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 47 81 0 ENST00000270509.2:c.4772C>T p.Pro1591Leu p.P1591L ENST00000270509 NM_032447.3 1591 cCa/cTa 0 +FBXL2 UCSF GRCh37 3 33418797 33418797 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 65 166 0 ENST00000484457.1:c.821C>T p.Thr274Ile p.T274I ENST00000484457 NM_012157.3 274 aCt/aTt 0 +FBXL5 UCSF GRCh37 4 15607372 15607372 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 28 78 0 ENST00000341285.3:c.2050C>T p.Arg684Ter p.R684* ENST00000341285 NM_001193534.1 684 Cga/Tga 0 +FBXO15 UCSF GRCh37 18 71797856 71797856 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 48 123 0 ENST00000419743.2:c.370C>T p.Pro124Ser p.P124S ENST00000419743 NM_001142958.1 124 Cct/Tct 0 +FBXO25 UCSF GRCh37 8 413085 413085 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 320 133 267 0 ENST00000382824.1:c.721C>T p.Pro241Ser p.P241S ENST00000382824 241 Cca/Tca 0 +FBXO34 UCSF GRCh37 14 55818764 55818764 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 152 97 239 0 ENST00000313833.4:c.1656G>A p.Lys552= p.K552= ENST00000313833 NM_017943.3 552 aaG/aaA 0 +FBXO36 UCSF GRCh37 2 230787285 230787285 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 36 77 0 ENST00000283946.3:c.56C>T p.Pro19Leu p.P19L ENST00000283946 NM_174899.4 19 cCt/cTt 0 +FBXO40 UCSF GRCh37 3 121341334 121341334 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 113 66 191 0 ENST00000338040.4:c.1058C>T p.Pro353Leu p.P353L ENST00000338040 NM_016298.3 353 cCt/cTt 0 +FCGBP UCSF GRCh37 19 40421162 40421162 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 37 50 0 ENST00000221347.6:c.2759C>T p.Thr920Met p.T920M ENST00000221347 NM_003890.2 920 aCg/aTg 0 +FCGR2B UCSF GRCh37 1 161642974 161642974 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 125 32 232 1 ENST00000358671.5:c.601G>A p.Gly201Ser p.G201S ENST00000358671 NM_001002275.2 201 Ggc/Agc 0 +FCRL1 UCSF GRCh37 1 157772450 157772450 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 29 72 0 ENST00000368176.3:c.324C>T p.Val108= p.V108= ENST00000368176 NM_001159398.1 108 gtC/gtT 0 +FCRL3 UCSF GRCh37 1 157659708 157659708 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 51 111 0 ENST00000368184.3:c.1691-1G>A p.X564_splice ENST00000368184 NM_052939.3 0 +FCRL5 UCSF GRCh37 1 157490246 157490246 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 8 21 0 ENST00000361835.3:c.2607C>T p.Leu869= p.L869= ENST00000361835 NM_001195388.1 869 ctC/ctT 0 +FCRLA UCSF GRCh37 1 161681016 161681016 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 33 52 1 ENST00000367959.2:c.320G>A p.Gly107Asp p.G107D ENST00000367959 NM_001184866.1 107 gGt/gAt 0 +FDXR UCSF GRCh37 17 72868192 72868192 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 23 42 0 ENST00000293195.5:c.146C>T p.Ala49Val p.A49V ENST00000293195 NM_001258014.1 49 gCt/gTt 0 +FEM1B UCSF GRCh37 15 68583057 68583057 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 124 255 0 ENST00000306917.4:c.1361C>T p.Ser454Phe p.S454F ENST00000306917 NM_015322.4 454 tCt/tTt 0 +FEM1C UCSF GRCh37 5 114860449 114860449 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 149 125 264 0 ENST00000274457.3:c.1410C>T p.Tyr470= p.Y470= ENST00000274457 NM_020177.2 470 taC/taT 0 +FER1L5 UCSF GRCh37 2 97361303 97361303 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 29 50 0 ENST00000397978.2:n.110G>A *37* ENST00000397978 0 +FER1L6 UCSF GRCh37 8 124978482 124978482 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 43 107 0 ENST00000399018.1:c.336G>A p.Lys112= p.K112= ENST00000399018 112 aaG/aaA 0 +FERD3L UCSF GRCh37 7 19184684 19184684 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 46 82 0 ENST00000275461.3:c.302C>T p.Ala101Val p.A101V ENST00000275461 NM_152898.2 101 gCc/gTc 0 +FERMT3 UCSF GRCh37 11 63978082 63978082 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 56 150 0 ENST00000279227.5:c.161-1G>A p.X54_splice ENST00000279227 NM_178443.2 0 +FES UCSF GRCh37 15 91428447 91428447 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 40 103 0 ENST00000328850.3:c.172G>A p.Gly58Ser p.G58S ENST00000328850 NM_002005.3 58 Ggc/Agc 0 +FGF7 UCSF GRCh37 15 49716728 49716728 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 83 175 0 ENST00000267843.4:c.234G>A p.Arg78= p.R78= ENST00000267843 NM_002009.3 78 agG/agA 0 +FGFBP2 UCSF GRCh37 4 15964451 15964451 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 8 81 0 ENST00000259989.6:c.302G>A p.Arg101His p.R101H ENST00000259989 NM_031950.3 101 cGc/cAc 0 +FGGY UCSF GRCh37 1 60133032 60133032 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 130 205 0 ENST00000303721.7:c.1374C>T p.Leu458= p.L458= ENST00000303721 NM_018291.3 458 ctC/ctT 0 +FHOD1 UCSF GRCh37 16 67265109 67265109 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 28 69 0 ENST00000258201.4:c.2649C>T p.Ala883= p.A883= ENST00000258201 NM_013241.2 883 gcC/gcT 0 +FIBCD1 UCSF GRCh37 9 133799169 133799169 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 30 62 0 ENST00000372338.4:c.811G>A p.Val271Met p.V271M ENST00000372338 NM_032843.4 271 Gtg/Atg 0 +FICD UCSF GRCh37 12 108912289 108912289 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 64 166 0 ENST00000552695.1:c.414C>T p.Asp138= p.D138= ENST00000552695 NM_007076.2 138 gaC/gaT 0 +FIGF UCSF GRCh37 X 15365310 15365310 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 17 129 157 0 ENST00000297904.3:c.914A>G p.Lys305Arg p.K305R ENST00000297904 NM_004469.4 305 aAg/aGg 0 +FIGF UCSF GRCh37 X 15376203 15376203 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 25 139 150 0 ENST00000297904.3:c.414C>T p.Asn138= p.N138= ENST00000297904 NM_004469.4 138 aaC/aaT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 163 142 226 0 ENST00000356889.4:c.1599A>G p.Thr533= p.T533= ENST00000356889 NM_001287495.1 533 acA/acG 0 +FITM2 UCSF GRCh37 20 42935488 42935488 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 50 109 0 ENST00000396825.3:c.566C>T p.Thr189Ile p.T189I ENST00000396825 NM_001080472.1 189 aCc/aTc 0 +FLG UCSF GRCh37 1 152276776 152276776 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 201 144 319 0 ENST00000368799.1:c.10586C>T p.Pro3529Leu p.P3529L ENST00000368799 NM_002016.1 3529 cCc/cTc 0 +FLJ43860 UCSF GRCh37 8 142517203 142517203 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 9 49 0 ENST00000430863.1:c.47G>A p.Gly16Asp p.G16D ENST00000430863 NM_207414.2 16 gGt/gAt 0 +FLNA UCSF GRCh37 X 153585643 153585643 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 3 33 32 0 ENST00000369850.3:c.4946-1G>A p.X1649_splice ENST00000369850 NM_001110556.1 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec Untested WXS Illumina HiSeq 159 106 247 0 ENST00000295956.4:c.6231C>G p.Asp2077Glu p.D2077E ENST00000295956 NM_001457.3 2077 gaC/gaG 0 +FLNB UCSF GRCh37 3 58067382 58067382 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 129 90 175 0 ENST00000295956.4:c.666C>T p.His222= p.H222= ENST00000295956 NM_001457.3 222 caC/caT 0 +FLNC UCSF GRCh37 7 128485171 128485171 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 37 94 0 ENST00000325888.8:c.3652C>T p.Pro1218Ser p.P1218S ENST00000325888 NM_001458.4 1218 Cct/Tct 0 +FLT3LG UCSF GRCh37 19 49983734 49983734 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 15 24 0 ENST00000594009.1:c.660+1G>A p.X220_splice ENST00000594009 NM_001204503.1 0 +FLT4 UCSF GRCh37 5 180057073 180057073 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 21 62 0 ENST00000261937.6:c.546G>A p.Glu182= p.E182= ENST00000261937 NM_182925.4 182 gaG/gaA 0 +FLVCR1 UCSF GRCh37 1 213062556 213062556 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 82 136 0 ENST00000366971.4:c.1482C>T p.Asn494= p.N494= ENST00000366971 NM_014053.3 494 aaC/aaT 0 +FMO4 UCSF GRCh37 1 171310886 171310886 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 39 88 0 ENST00000367749.3:c.1585C>T p.Leu529Phe p.L529F ENST00000367749 NM_002022.1 529 Ctt/Ttt 0 +FMO5 UCSF GRCh37 1 146687361 146687361 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 74 198 0 ENST00000254090.4:c.287C>T p.Ala96Val p.A96V ENST00000254090 NM_001461.3 96 gCc/gTc 0 +FN1 UCSF GRCh37 2 216296570 216296570 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 112 218 0 ENST00000359671.1:c.533C>T p.Thr178Ile p.T178I ENST00000359671 178 aCc/aTc 0 +FNDC1 UCSF GRCh37 6 159642672 159642672 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 69 178 0 ENST00000297267.9:c.710C>T p.Ser237Phe p.S237F ENST00000297267 NM_032532.2 237 tCt/tTt 0 +FNDC1 UCSF GRCh37 6 159653946 159653946 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 45 115 0 ENST00000297267.9:c.2402C>T p.Ala801Val p.A801V ENST00000297267 NM_032532.2 801 gCg/gTg 0 +FOXA2 UCSF GRCh37 20 22564892 22564892 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 20 44 0 ENST00000377115.4:c.7G>A p.Gly3Arg p.G3R ENST00000377115 NM_153675.2 3 Gga/Aga 0 +FOXA2 UCSF GRCh37 20 22563629 22563629 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 63 0 ENST00000377115.4:c.233C>T p.Ala78Val p.A78V ENST00000377115 NM_153675.2 78 gCg/gTg 0 +FOXJ2 UCSF GRCh37 12 8203198 8203198 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 59 152 0 ENST00000162391.3:c.1618G>A p.Ala540Thr p.A540T ENST00000162391 NM_018416.2 540 Gca/Aca 0 +FREM1 UCSF GRCh37 9 14824818 14824818 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 81 190 0 ENST00000380880.3:c.2054C>T p.Pro685Leu p.P685L ENST00000380880 685 cCt/cTt 0 +FREM2 UCSF GRCh37 13 39264884 39264884 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 79 194 0 ENST00000280481.7:c.3403G>A p.Ala1135Thr p.A1135T ENST00000280481 NM_207361.4 1135 Gct/Act 0 +FRG2 UCSF GRCh37 4 190946914 190946914 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 62 207 0 ENST00000378763.1:c.639C>T p.Leu213= p.L213= ENST00000378763 NM_001005217.1 213 ctC/ctT 0 +FRMD4B UCSF GRCh37 3 69336917 69336917 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 52 81 0 ENST00000398540.3:c.487G>A p.Ala163Thr p.A163T ENST00000398540 NM_015123.1 163 Gcc/Acc 0 +FRMD5 UCSF GRCh37 15 44180383 44180383 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 49 112 0 ENST00000417257.1:c.874G>A p.Ala292Thr p.A292T ENST00000417257 NM_032892.3 292 Gcc/Acc 0 +FRYL UCSF GRCh37 4 48514613 48514613 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 74 179 0 ENST00000358350.4:c.8030C>T p.Pro2677Leu p.P2677L ENST00000358350 NM_015030.1 2677 cCc/cTc 0 +FSCB UCSF GRCh37 14 44974174 44974174 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 18 88 0 ENST00000340446.4:c.2017C>T p.Pro673Ser p.P673S ENST00000340446 NM_032135.3 673 Cca/Tca 0 +FSIP2 UCSF GRCh37 2 186665922 186665922 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 153 103 252 0 ENST00000424728.1:c.11889G>A p.Gln3963= p.Q3963= ENST00000424728 3963 caG/caA 0 +FTCD UCSF GRCh37 21 47575416 47575416 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 29 69 0 ENST00000291670.5:c.22G>A p.Val8Ile p.V8I ENST00000291670 NM_006657.2 8 Gtc/Atc 0 +FTSJD1 UCSF GRCh37 16 71318179 71318179 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 47 122 0 ENST00000338099.5:c.1645G>A p.Val549Ile p.V549I ENST00000338099 549 Gtt/Att 0 +FTSJD1 UCSF GRCh37 16 71318132 71318132 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 45 132 0 ENST00000338099.5:c.1692G>A p.Glu564= p.E564= ENST00000338099 564 gaG/gaA 0 +FUBP3 UCSF GRCh37 9 133506129 133506129 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 50 91 0 ENST00000319725.9:c.1232C>T p.Pro411Leu p.P411L ENST00000319725 NM_003934.1 411 cCc/cTc 0 +FZD6 UCSF GRCh37 8 104337348 104337348 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 137 246 0 ENST00000358755.4:c.1014G>A p.Leu338= p.L338= ENST00000358755 NM_001164616.1 338 ctG/ctA 0 +FZD8 UCSF GRCh37 10 35928730 35928730 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 14 77 0 ENST00000374694.1:c.1628C>T p.Pro543Leu p.P543L ENST00000374694 NM_031866.2 543 cCc/cTc 0 +FZD9 UCSF GRCh37 7 72849769 72849769 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 39 95 0 ENST00000344575.3:c.1432C>T p.Leu478Phe p.L478F ENST00000344575 NM_003508.2 478 Ctt/Ttt 0 +G2E3 UCSF GRCh37 14 31061611 31061611 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 80 117 0 ENST00000206595.6:c.320G>A p.Gly107Glu p.G107E ENST00000206595 NM_017769.3 107 gGa/gAa 0 +G3BP1 UCSF GRCh37 5 151176891 151176891 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 61 148 0 ENST00000356245.3:c.643C>T p.Pro215Ser p.P215S ENST00000356245 NM_005754.2 215 Cct/Tct 0 +G3BP1 UCSF GRCh37 5 151176792 151176792 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 54 79 0 ENST00000356245.3:c.544G>A p.Asp182Asn p.D182N ENST00000356245 NM_005754.2 182 Gac/Aac 0 +GABARAP UCSF GRCh37 17 7144983 7144983 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 89 185 0 ENST00000302386.5:c.106G>A p.Ala36Thr p.A36T ENST00000302386 NM_007278.1 36 Gct/Act 0 +GABBR2 UCSF GRCh37 9 101304178 101304178 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 47 120 0 ENST00000259455.2:c.607C>T p.Gln203Ter p.Q203* ENST00000259455 NM_005458.7 203 Caa/Taa 0 +GABPA UCSF GRCh37 21 27136631 27136631 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 62 183 0 ENST00000354828.3:c.913G>A p.Glu305Lys p.E305K ENST00000354828 NM_001197297.1 305 Gaa/Aaa 0 +GABRA4 UCSF GRCh37 4 46930490 46930490 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 134 98 266 1 ENST00000264318.3:c.1417G>A p.Ala473Thr p.A473T ENST00000264318 NM_000809.3 473 Gct/Act 0 +GABRB1 UCSF GRCh37 4 47163377 47163377 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 170 144 306 0 ENST00000295454.3:c.352G>A p.Val118Ile p.V118I ENST00000295454 NM_000812.3 118 Gta/Ata 0 +GABRB3 UCSF GRCh37 15 26812804 26812804 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 58 160 0 ENST00000311550.5:c.759C>T p.Pro253= p.P253= ENST00000311550 NM_000814.5 253 ccC/ccT 0 +GABRR3 UCSF GRCh37 3 97720581 97720581 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 87 63 130 0 ENST00000472788.1:c.785T>C p.Val262Ala p.V262A ENST00000472788 NM_001105580.2 262 gTg/gCg 0 +GAL3ST2 UCSF GRCh37 2 242743054 242743054 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 7 15 0 ENST00000192314.6:c.670G>A p.Val224Met p.V224M ENST00000192314 NM_022134.2 224 Gtg/Atg 0 +GALNT1 UCSF GRCh37 18 33271053 33271053 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 177 145 263 0 ENST00000269195.5:c.1056C>T p.Tyr352= p.Y352= ENST00000269195 NM_020474.3 352 taC/taT 0 +GALNT4 UCSF GRCh37 12 89917070 89917070 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 114 216 0 ENST00000529983.2:c.1257G>A p.Leu419= p.L419= ENST00000529983 NM_003774.4 419 ttG/ttA 0 +GALNT5 UCSF GRCh37 2 158115847 158115847 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 77 212 0 ENST00000259056.4:c.1253G>A p.Ser418Asn p.S418N ENST00000259056 NM_014568.1 418 aGt/aAt 0 +GALNT7 UCSF GRCh37 4 174225262 174225262 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 60 147 0 ENST00000265000.4:c.1382C>T p.Thr461Ile p.T461I ENST00000265000 NM_017423.2 461 aCt/aTt 0 +GAPDHS UCSF GRCh37 19 36034723 36034723 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 29 65 0 ENST00000222286.4:c.1050G>A p.Glu350= p.E350= ENST00000222286 NM_014364.4 350 gaG/gaA 0 +GAPVD1 UCSF GRCh37 9 128099513 128099513 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 57 133 0 ENST00000394104.2:c.2520G>A p.Val840= p.V840= ENST00000394104 NM_001282679.1 840 gtG/gtA 0 +GARNL3 UCSF GRCh37 9 130098462 130098462 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 51 137 0 ENST00000373387.4:c.929G>A p.Gly310Glu p.G310E ENST00000373387 NM_032293.4 310 gGa/gAa 0 +GARNL3 UCSF GRCh37 9 130149546 130149546 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 61 130 0 ENST00000373387.4:c.2463C>T p.Ala821= p.A821= ENST00000373387 NM_032293.4 821 gcC/gcT 0 +GAS6 UCSF GRCh37 13 114542772 114542772 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 55 129 0 ENST00000327773.6:c.395C>T p.Ala132Val p.A132V ENST00000327773 NM_000820.2 132 gCc/gTc 0 +GBP3 UCSF GRCh37 1 89476628 89476628 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 183 186 0 ENST00000370481.4:c.1321C>T p.Leu441= p.L441= ENST00000370481 NM_018284.2 441 Ctg/Ttg 0 +GDAP2 UCSF GRCh37 1 118420712 118420712 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 57 130 0 ENST00000369443.5:c.1365G>A p.Val455= p.V455= ENST00000369443 NM_017686.3 455 gtG/gtA 0 +GDF15 UCSF GRCh37 19 18499125 18499125 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 14 33 0 ENST00000252809.3:c.307C>T p.Leu103= p.L103= ENST00000252809 NM_004864.2 103 Ctg/Ttg 0 +GDF2 UCSF GRCh37 10 48416610 48416610 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 26 18 56 0 ENST00000249598.1:c.84G>A p.Trp28Ter p.W28* ENST00000249598 NM_016204.1 28 tgG/tgA 0 +GFM2 UCSF GRCh37 5 74034354 74034354 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 62 161 0 ENST00000296805.3:c.1193C>T p.Ala398Val p.A398V ENST00000296805 NM_032380.4 398 gCc/gTc 0 +GGA1 UCSF GRCh37 22 38028003 38028003 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 29 88 0 ENST00000343632.4:c.1529G>A p.Ser510Asn p.S510N ENST00000343632 NM_013365.4 510 aGc/aAc 0 +GGA3 UCSF GRCh37 17 73238537 73238537 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 143 112 232 0 ENST00000537686.1:c.*61G>A *21* ENST00000537686 0 +GGCX UCSF GRCh37 2 85778691 85778691 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 77 185 0 ENST00000233838.4:c.1652C>T p.Thr551Ile p.T551I ENST00000233838 NM_000821.5 551 aCt/aTt 0 +GGCX UCSF GRCh37 2 85780478 85780478 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 83 184 0 ENST00000233838.4:c.1032G>A p.Val344= p.V344= ENST00000233838 NM_000821.5 344 gtG/gtA 0 +GHDC UCSF GRCh37 17 40344541 40344541 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 83 177 0 ENST00000301671.8:c.607G>A p.Ala203Thr p.A203T ENST00000301671 203 Gct/Act 0 +GHDC UCSF GRCh37 17 40342239 40342239 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 82 175 0 ENST00000301671.8:c.1338G>A p.Arg446= p.R446= ENST00000301671 446 agG/agA 0 +GIMAP8 UCSF GRCh37 7 150171727 150171727 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 58 132 0 ENST00000307271.3:c.1309+1G>A p.X437_splice ENST00000307271 NM_175571.2 0 +GIP UCSF GRCh37 17 47038273 47038273 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 10 21 0 ENST00000357424.2:c.427G>A p.Asp143Asn p.D143N ENST00000357424 NM_004123.2 143 Gat/Aat 0 +GIT2 UCSF GRCh37 12 110405292 110405292 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 63 136 0 ENST00000355312.3:c.735G>A p.Gln245= p.Q245= ENST00000355312 NM_057169.3 245 caG/caA 0 +GJA5 UCSF GRCh37 1 147230420 147230420 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 89 186 0 ENST00000271348.2:c.927G>A p.Gly309= p.G309= ENST00000271348 NM_005266.6 309 ggG/ggA 0 +GJB6 UCSF GRCh37 13 20796987 20796987 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 56 130 0 ENST00000241124.6:c.633C>T p.Cys211= p.C211= ENST00000241124 NM_006783.4 211 tgC/tgT 0 +GLI2 UCSF GRCh37 2 121747119 121747119 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 15 31 0 ENST00000361492.4:c.3629G>A p.Gly1210Glu p.G1210E ENST00000361492 NM_005270.4 1210 gGa/gAa 0 +GLOD5 UCSF GRCh37 X 48631750 48631750 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 125 110 0 ENST00000303227.6:c.382G>A p.Gly128Arg p.G128R ENST00000303227 NM_001080489.2 128 Ggg/Agg 0 +GLS2 UCSF GRCh37 12 56866533 56866533 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 90 199 0 ENST00000311966.4:c.1452C>T p.Asn484= p.N484= ENST00000311966 NM_001280797.1 484 aaC/aaT 0 +GLT25D1 UCSF GRCh37 19 17691630 17691630 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 23 83 0 ENST00000252599.4:c.1517C>T p.Ala506Val p.A506V ENST00000252599 NM_024656.2 506 gCc/gTc 0 +GLT25D1 UCSF GRCh37 19 17688209 17688209 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 7 9 0 ENST00000252599.4:c.1066G>A p.Glu356Lys p.E356K ENST00000252599 NM_024656.2 356 Gag/Aag 0 +GLT6D1 UCSF GRCh37 9 138516249 138516249 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 59 119 0 ENST00000371763.1:c.525C>T p.Asn175= p.N175= ENST00000371763 NM_182974.2 175 aaC/aaT 0 +GNAI3 UCSF GRCh37 1 110116530 110116530 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 83 182 0 ENST00000369851.4:c.174G>A p.Glu58= p.E58= ENST00000369851 NM_006496.3 58 gaG/gaA 0 +GNB2 UCSF GRCh37 7 100275839 100275839 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 96 161 0 ENST00000303210.4:c.616G>A p.Ala206Thr p.A206T ENST00000303210 NM_005273.3 206 Gcc/Acc 0 +GNG2 UCSF GRCh37 14 52433376 52433376 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 94 216 0 ENST00000335281.4:c.187G>A p.Glu63Lys p.E63K ENST00000335281 NM_001243774.1 63 Gag/Aag 0 +GNL1 UCSF GRCh37 6 30514932 30514932 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 50 124 0 ENST00000376621.3:c.1398C>T p.Asp466= p.D466= ENST00000376621 NM_005275.3 466 gaC/gaT 0 +GNL3L UCSF GRCh37 X 54570681 54570681 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 4 19 33 0 ENST00000336470.4:c.552G>A p.Glu184= p.E184= ENST00000336470 NM_019067.5 184 gaG/gaA 0 +GNPAT UCSF GRCh37 1 231386751 231386751 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 119 97 178 0 ENST00000366647.4:c.123G>A p.Glu41= p.E41= ENST00000366647 NM_014236.3 41 gaG/gaA 0 +GON4L UCSF GRCh37 1 155735038 155735038 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 151 121 263 0 ENST00000368331.1:c.4226G>A p.Gly1409Glu p.G1409E ENST00000368331 NM_001037533.1 1409 gGa/gAa 0 +GOT1L1 UCSF GRCh37 8 37796328 37796328 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 86 192 0 ENST00000307599.4:c.187G>A p.Asp63Asn p.D63N ENST00000307599 NM_152413.2 63 Gat/Aat 0 +GP1BA UCSF GRCh37 17 4836177 4836177 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 95 187 0 ENST00000329125.5:c.278C>T p.Pro93Leu p.P93L ENST00000329125 NM_000173.5 93 cCa/cTa 0 +GPAA1 UCSF GRCh37 8 145138941 145138941 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 70 104 0 ENST00000355091.4:c.614C>T p.Thr205Ile p.T205I ENST00000355091 NM_003801.3 205 aCt/aTt 0 +GPATCH1 UCSF GRCh37 19 33608917 33608917 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 56 128 0 ENST00000170564.2:c.2383G>A p.Asp795Asn p.D795N ENST00000170564 NM_018025.2 795 Gac/Aac 0 +GPATCH3 UCSF GRCh37 1 27217646 27217646 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 43 79 0 ENST00000361720.5:c.1433C>T p.Ser478Phe p.S478F ENST00000361720 NM_022078.2 478 tCc/tTc 0 +GPC5 UCSF GRCh37 13 92345775 92345775 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 34 113 0 ENST00000377067.3:c.660G>A p.Leu220= p.L220= ENST00000377067 NM_004466.4 220 ctG/ctA 0 +GPR108 UCSF GRCh37 19 6734315 6734315 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 15 36 0 ENST00000264080.7:c.378C>T p.Val126= p.V126= ENST00000264080 NM_001080452.1 126 gtC/gtT 0 +GPR112 UCSF GRCh37 X 135432197 135432197 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 106 112 0 ENST00000370652.1:c.6332C>T p.Thr2111Ile p.T2111I ENST00000370652 2111 aCc/aTc 0 +GPR113 UCSF GRCh37 2 26534502 26534502 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 73 101 0 ENST00000311519.1:c.2094C>T p.Ser698= p.S698= ENST00000311519 NM_001145168.1 698 agC/agT 0 +GPR116 UCSF GRCh37 6 46839599 46839599 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 126 99 197 0 ENST00000265417.7:c.1392A>G p.Lys464= p.K464= ENST00000265417 NM_015234.4 464 aaA/aaG 0 +GPR125 UCSF GRCh37 4 22446699 22446699 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 45 117 0 ENST00000334304.5:c.603G>A p.Trp201Ter p.W201* ENST00000334304 NM_145290.3 201 tgG/tgA 0 +GPR158 UCSF GRCh37 10 25701324 25701324 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 338 108 265 0 ENST00000376351.3:c.1257C>T p.Ala419= p.A419= ENST00000376351 NM_020752.2 419 gcC/gcT 0 +GPR179 UCSF GRCh37 17 36499172 36499172 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 62 143 0 ENST00000342292.4:c.501C>T p.Thr167= p.T167= ENST00000342292 NM_001004334.2 167 acC/acT 0 +GPR26 UCSF GRCh37 10 125426578 125426578 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 9 31 0 ENST00000284674.1:c.655G>T p.Asp219Tyr p.D219Y ENST00000284674 NM_153442.3 219 Gac/Tac 0 +GPR32 UCSF GRCh37 19 51274536 51274536 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 54 120 0 ENST00000270590.4:c.679G>A p.Gly227Arg p.G227R ENST00000270590 NM_001506.2 227 Ggg/Agg 0 +GPR35 UCSF GRCh37 2 241569429 241569429 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 43 96 0 ENST00000319838.5:c.60G>A p.Lys20= p.K20= ENST00000319838 NM_001195381.1 20 aaG/aaA 0 +GPR37 UCSF GRCh37 7 124404799 124404799 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 26 51 0 ENST00000303921.2:c.232G>A p.Ala78Thr p.A78T ENST00000303921 NM_005302.3 78 Gca/Aca 0 +GPR56 UCSF GRCh37 16 57687213 57687213 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 17 41 0 ENST00000567835.1:c.586G>A p.Ala196Thr p.A196T ENST00000567835 196 Gcc/Acc 0 +GPR56 UCSF GRCh37 16 57693441 57693441 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 48 110 0 ENST00000567835.1:c.1421G>A p.Gly474Asp p.G474D ENST00000567835 474 gGc/gAc 0 +GPR64 UCSF GRCh37 X 19028836 19028836 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 115 132 0 ENST00000379869.3:c.1160C>T p.Ala387Val p.A387V ENST00000379869 NM_001079858.2 387 gCt/gTt 0 +GPR82 UCSF GRCh37 X 41586742 41586742 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 96 97 0 ENST00000302548.4:c.463C>T p.Leu155= p.L155= ENST00000302548 NM_080817.4 155 Cta/Tta 0 +GPR98 UCSF GRCh37 5 90083954 90083954 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 140 94 198 0 ENST00000405460.2:c.13720G>A p.Asp4574Asn p.D4574N ENST00000405460 NM_032119.3 4574 Gac/Aac 0 +GPRIN1 UCSF GRCh37 5 176025149 176025149 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 90 193 0 ENST00000303991.4:c.1687C>T p.Pro563Ser p.P563S ENST00000303991 NM_052899.2 563 Ccc/Tcc 0 +GPS1 UCSF GRCh37 17 80010317 80010317 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 19 34 0 ENST00000306823.6:c.33+477C>T *11* ENST00000306823 0 +GPSM1 UCSF GRCh37 9 139252516 139252516 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 19 51 0 ENST00000440944.1:c.1872G>A p.Arg624= p.R624= ENST00000440944 NM_001145638.2 624 cgG/cgA 0 +GPX3 UCSF GRCh37 5 150407620 150407620 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 23 72 0 ENST00000388825.4:c.610G>A p.Val204Ile p.V204I ENST00000388825 NM_002084.3 204 Gtc/Atc 0 +GPX8 UCSF GRCh37 5 54456129 54456129 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 81 189 0 ENST00000503787.1:c.109C>T p.Leu37= p.L37= ENST00000503787 NM_001008397.2 37 Cta/Tta 0 +GREB1L UCSF GRCh37 18 18983857 18983857 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 175 141 316 0 ENST00000424526.1:c.734C>T p.Ala245Val p.A245V ENST00000424526 NM_001142966.1 245 gCt/gTt 0 +GREB1L UCSF GRCh37 18 19080545 19080545 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 19 42 0 ENST00000424526.1:c.4014C>T p.Phe1338= p.F1338= ENST00000424526 NM_001142966.1 1338 ttC/ttT 0 +GRID1 UCSF GRCh37 10 87966175 87966175 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 44 99 0 ENST00000327946.7:c.466C>T p.Leu156= p.L156= ENST00000327946 NM_017551.2 156 Ctg/Ttg 0 +GRIK5 UCSF GRCh37 19 42558519 42558519 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 35 82 0 ENST00000262895.3:c.1009G>A p.Ala337Thr p.A337T ENST00000262895 NM_002088.4 337 Gcc/Acc 0 +GRIN2A UCSF GRCh37 16 9858036 9858036 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 231 95 200 0 ENST00000330684.3:c.3365G>A p.Gly1122Asp p.G1122D ENST00000330684 NM_001134407.1 1122 gGt/gAt 0 +GRIN2A UCSF GRCh37 16 9923338 9923338 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 206 80 173 0 ENST00000330684.3:c.1949C>T p.Ala650Val p.A650V ENST00000330684 NM_001134407.1 650 gCt/gTt 0 +GRIN2C UCSF GRCh37 17 72848181 72848181 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 10 16 0 ENST00000293190.5:c.969C>T p.Pro323= p.P323= ENST00000293190 NM_000835.4 323 ccC/ccT 0 +GRIN3A UCSF GRCh37 9 104499668 104499668 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 43 123 0 ENST00000361820.3:c.594C>T p.Ala198= p.A198= ENST00000361820 NM_133445.2 198 gcC/gcT 0 +GRK6 UCSF GRCh37 5 176862108 176862108 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 19 54 0 ENST00000355472.5:c.1043C>T p.Thr348Ile p.T348I ENST00000355472 NM_002082.3 348 aCc/aTc 0 +GRK7 UCSF GRCh37 3 141497563 141497563 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 49 104 0 ENST00000264952.2:c.437C>T p.Ala146Val p.A146V ENST00000264952 NM_139209.2 146 gCa/gTa 0 +GSDMD UCSF GRCh37 8 144642028 144642028 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 23 56 0 ENST00000262580.4:c.299G>A p.Gly100Glu p.G100E ENST00000262580 NM_024736.6 100 gGa/gAa 0 +GTDC1 UCSF GRCh37 2 144714815 144714815 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 63 153 0 ENST00000344850.4:c.1077C>T p.Cys359= p.C359= ENST00000344850 359 tgC/tgT 0 +GTF2B UCSF GRCh37 1 89353037 89353037 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 171 129 260 0 ENST00000370500.5:c.31C>T p.Pro11Ser p.P11S ENST00000370500 NM_001514.5 11 Cca/Tca 0 +GTF2E2 UCSF GRCh37 8 30437797 30437797 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 183 125 284 0 ENST00000355904.4:c.759+1G>A p.X253_splice ENST00000355904 NM_002095.4 0 +GTF2F1 UCSF GRCh37 19 6380678 6380678 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 43 90 0 ENST00000394456.5:c.1255G>A p.Ala419Thr p.A419T ENST00000394456 NM_002096.2 419 Gca/Aca 0 +GTF2IRD1 UCSF GRCh37 7 73973225 73973225 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 42 95 0 ENST00000265755.3:c.2187C>T p.Val729= p.V729= ENST00000265755 NM_005685.3 729 gtC/gtT 0 +GTF3C2 UCSF GRCh37 2 27551736 27551736 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 54 93 0 ENST00000264720.3:c.2102C>T p.Thr701Ile p.T701I ENST00000264720 NM_001035521.2 701 aCt/aTt 0 +GYG1 UCSF GRCh37 3 148744574 148744574 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 61 152 0 ENST00000345003.4:c.907C>T p.Leu303= p.L303= ENST00000345003 NM_004130.3 303 Ctg/Ttg 0 +GYS1 UCSF GRCh37 19 49494637 49494637 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 93 159 0 ENST00000323798.3:c.222G>A p.Arg74= p.R74= ENST00000323798 NM_002103.4 74 agG/agA 0 +GZMA UCSF GRCh37 5 54404196 54404196 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 69 165 0 ENST00000274306.6:c.601C>T p.Leu201Phe p.L201F ENST00000274306 NM_006144.3 201 Ctc/Ttc 0 +GZMH UCSF GRCh37 14 25076612 25076612 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 26 71 0 ENST00000216338.4:c.340C>T p.Leu114= p.L114= ENST00000216338 NM_033423.4 114 Ctg/Ttg 0 +HAS1 UCSF GRCh37 19 52217087 52217087 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 13 30 0 ENST00000222115.1:c.1330G>A p.Ala444Thr p.A444T ENST00000222115 NM_001523.2 444 Gcc/Acc 0 +HAT1 UCSF GRCh37 2 172803277 172803277 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 74 158 0 ENST00000264108.4:c.162G>A p.Glu54= p.E54= ENST00000264108 NM_003642.3 54 gaG/gaA 0 +HBQ1 UCSF GRCh37 16 230818 230818 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 7 12 0 ENST00000199708.2:c.249G>A p.Ala83= p.A83= ENST00000199708 NM_005331.4 83 gcG/gcA 0 +HCK UCSF GRCh37 20 30674508 30674508 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 31 72 0 ENST00000534862.1:c.853G>A p.Glu285Lys p.E285K ENST00000534862 NM_001172132.1 285 Gag/Aag 0 +HCN4 UCSF GRCh37 15 73617356 73617356 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 64 111 0 ENST00000261917.3:c.1918G>A p.Val640Ile p.V640I ENST00000261917 NM_005477.2 640 Gtc/Atc 0 +HCRTR1 UCSF GRCh37 1 32087185 32087185 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 65 160 0 ENST00000373706.5:c.730G>A p.Gly244Ser p.G244S ENST00000373706 244 Ggc/Agc 0 +HDAC3 UCSF GRCh37 5 141004869 141004869 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 207 138 295 0 ENST00000305264.3:c.1123G>A p.Val375Ile p.V375I ENST00000305264 NM_003883.3 375 Gtc/Atc 0 +HDGFRP2 UCSF GRCh37 19 4499544 4499544 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 19 53 0 ENST00000301284.4:c.1632C>T p.Thr544= p.T544= ENST00000301284 NM_001001520.1 544 acC/acT 0 +HEATR1 UCSF GRCh37 1 236744649 236744649 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 196 124 244 0 ENST00000366582.3:c.2628C>T p.Ser876= p.S876= ENST00000366582 NM_018072.5 876 agC/agT 0 +HEATR5B UCSF GRCh37 2 37235830 37235830 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 95 201 0 ENST00000233099.5:c.4446C>T p.Arg1482= p.R1482= ENST00000233099 NM_019024.1 1482 cgC/cgT 0 +HEATR8 UCSF GRCh37 1 55145099 55145099 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 23 73 0 ENST00000421030.2:c.2213G>A p.Arg738Lys p.R738K ENST00000421030 NM_001039464.2 738 aGg/aAg 0 +HEG1 UCSF GRCh37 3 124731715 124731715 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 161 130 305 0 ENST00000311127.4:c.2708G>A p.Arg903Lys p.R903K ENST00000311127 NM_020733.1 903 aGg/aAg 0 +HEG1 UCSF GRCh37 3 124746251 124746251 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 131 73 162 0 ENST00000311127.4:c.711G>A p.Glu237= p.E237= ENST00000311127 NM_020733.1 237 gaG/gaA 0 +HEG1 UCSF GRCh37 3 124692647 124692647 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 185 158 283 0 ENST00000311127.4:c.3924C>T p.Gly1308= p.G1308= ENST00000311127 NM_020733.1 1308 ggC/ggT 0 +HELZ UCSF GRCh37 17 65144795 65144795 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 186 106 290 0 ENST00000358691.5:c.2511G>A p.Glu837= p.E837= ENST00000358691 NM_014877.3 837 gaG/gaA 0 +HEMGN UCSF GRCh37 9 100693034 100693034 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 200 191 371 0 ENST00000259456.3:c.643C>T p.Pro215Ser p.P215S ENST00000259456 NM_018437.4 215 Cct/Tct 0 +HEMGN UCSF GRCh37 9 100692353 100692353 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 144 124 229 0 ENST00000259456.3:c.1324C>T p.Gln442Ter p.Q442* ENST00000259456 NM_018437.4 442 Cag/Tag 0 +HEPACAM UCSF GRCh37 11 124793894 124793894 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 18 40 0 ENST00000298251.4:c.440G>A p.Arg147Lys p.R147K ENST00000298251 NM_152722.4 147 aGg/aAg 0 +HERC2 UCSF GRCh37 15 28412840 28412840 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 103 203 0 ENST00000261609.7:c.10547C>T p.Thr3516Ile p.T3516I ENST00000261609 NM_004667.5 3516 aCc/aTc 0 +HERC2 UCSF GRCh37 15 28518093 28518093 + synonymous_variant Silent SNP C C T snp132_rs59154112 P18_Rec Untested WXS Illumina HiSeq 73 32 83 0 ENST00000261609.7:c.858G>A p.Gln286= p.Q286= ENST00000261609 NM_004667.5 286 caG/caA 0 +HERC2 UCSF GRCh37 15 28482229 28482229 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 94 284 0 ENST00000261609.7:c.3883C>T p.Leu1295= p.L1295= ENST00000261609 NM_004667.5 1295 Ctg/Ttg 0 +HESX1 UCSF GRCh37 3 57232851 57232851 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 287 188 402 0 ENST00000295934.3:c.287G>A p.Arg96Lys p.R96K ENST00000295934 NM_003865.2 96 aGa/aAa 0 +HFM1 UCSF GRCh37 1 91788756 91788756 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 96 242 0 ENST00000370425.3:c.2428G>A p.Val810Ile p.V810I ENST00000370425 NM_001017975.3 810 Gtt/Att 0 +HGF UCSF GRCh37 7 81374400 81374400 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 54 135 0 ENST00000222390.5:c.662G>A p.Gly221Asp p.G221D ENST00000222390 NM_000601.4 221 gGt/gAt 0 +HHIP UCSF GRCh37 4 145659036 145659036 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 121 232 0 ENST00000296575.3:c.2030C>T p.Thr677Ile p.T677I ENST00000296575 NM_022475.2 677 aCc/aTc 0 +HIATL1 UCSF GRCh37 9 97221478 97221478 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 86 176 0 ENST00000375344.3:c.1305G>A p.Gly435= p.G435= ENST00000375344 NM_032558.2 435 ggG/ggA 0 +HIPK2 UCSF GRCh37 7 139257685 139257685 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 14 25 0 ENST00000406875.3:c.3585C>T p.Tyr1195= p.Y1195= ENST00000406875 NM_022740.4 1195 taC/taT 0 +HIVEP1 UCSF GRCh37 6 12122847 12122847 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 40 112 0 ENST00000379388.2:c.2819T>A p.Leu940Gln p.L940Q ENST00000379388 NM_002114.2 940 cTg/cAg 0 +HIVEP3 UCSF GRCh37 1 42049788 42049788 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 55 119 0 ENST00000247584.5:c.681C>T p.Phe227= p.F227= ENST00000247584 227 ttC/ttT 0 +HKDC1 UCSF GRCh37 10 71018671 71018671 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 44 95 0 ENST00000354624.5:c.2172C>T p.Tyr724= p.Y724= ENST00000354624 NM_025130.3 724 taC/taT 0 +HLA-C UCSF GRCh37 6 31238956 31238956 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 10 94 0 ENST00000376228.5:c.513G>A p.Leu171= p.L171= ENST00000376228 NM_002117.5 171 ttG/ttA 0 +HLA-DQA1 UCSF GRCh37 6 32609823 32609823 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 18 38 52 0 ENST00000343139.5:c.406G>A p.Asp136Asn p.D136N ENST00000343139 NM_002122.3 136 Gac/Aac 0 +HLA-DQA2 UCSF GRCh37 6 32713642 32713642 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 276 45 352 0 ENST00000374940.3:c.406G>A p.Asp136Asn p.D136N ENST00000374940 NM_020056.4 136 Gac/Aac 0 +HLA-DRA UCSF GRCh37 6 32411128 32411128 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 111 207 0 ENST00000395388.2:c.495G>A p.Arg165= p.R165= ENST00000395388 NM_019111.4 165 agG/agA 0 +HLA-DRB5 UCSF GRCh37 6 32489786 32489786 + missense_variant Missense_Mutation SNP T T G 1000g2010nov_all_0.101,1000g2011may_all_0.1594,snp132_rs41541218 P18_Rec Untested WXS Illumina HiSeq 44 8 58 1 ENST00000374975.3:c.266A>C p.Tyr89Ser p.Y89S ENST00000374975 NM_002125.3 89 tAc/tCc 0 +HLA-DRB5 UCSF GRCh37 6 32489806 32489806 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.029,snp132_rs1059349 P18_Rec Untested WXS Illumina HiSeq 56 8 64 1 ENST00000374975.3:c.246G>A p.Leu82= p.L82= ENST00000374975 NM_002125.3 82 ctG/ctA 0 +HMCN1 UCSF GRCh37 1 186026477 186026477 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 86 204 0 ENST00000271588.4:c.7256C>T p.Thr2419Ile p.T2419I ENST00000271588 NM_031935.2 2419 aCc/aTc 0 +HMCN1 UCSF GRCh37 1 186136014 186136014 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 68 149 0 ENST00000271588.4:c.15514C>T p.Arg5172Cys p.R5172C ENST00000271588 NM_031935.2 5172 Cgc/Tgc 0 +HMCN1 UCSF GRCh37 1 186084079 186084079 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 167 139 266 0 ENST00000271588.4:c.11404+1G>A p.X3802_splice ENST00000271588 NM_031935.2 0 +HMGB1 UCSF GRCh37 13 31036689 31036689 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 218 118 345 0 ENST00000339872.4:c.457G>A p.Glu153Lys p.E153K ENST00000339872 153 Gaa/Aaa 0 +HMX2 UCSF GRCh37 10 124909357 124909357 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 26 43 0 ENST00000339992.3:c.540C>T p.Ala180= p.A180= ENST00000339992 NM_005519.1 180 gcC/gcT 0 +HN1L UCSF GRCh37 16 1741846 1741846 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 88 84 0 ENST00000248098.3:c.196G>A p.Gly66Ser p.G66S ENST00000248098 NM_144570.2 66 Ggt/Agt 0 +HNF1A UCSF GRCh37 12 121432194 121432194 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec Untested WXS Illumina HiSeq 10 12 23 0 ENST00000257555.6:c.941C>G p.Pro314Arg p.P314R ENST00000257555 314 cCc/cGc 0 +HNRNPC UCSF GRCh37 14 21699190 21699190 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 155 113 237 0 ENST00000420743.2:c.283G>A p.Ala95Thr p.A95T ENST00000420743 95 Gca/Aca 0 +HNRNPR UCSF GRCh37 1 23640128 23640128 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 65 180 0 ENST00000302271.6:c.1085C>T p.Ser362Phe p.S362F ENST00000302271 362 tCt/tTt 0 +HNRNPR UCSF GRCh37 1 23664278 23664278 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 150 83 182 0 ENST00000302271.6:c.353C>T p.Ser118Phe p.S118F ENST00000302271 118 tCc/tTc 0 +HNRNPU UCSF GRCh37 1 245021312 245021312 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 52 100 0 ENST00000283179.9:c.1494+1G>A p.X498_splice ENST00000283179 0 +HOMER1 UCSF GRCh37 5 78746835 78746835 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 60 140 0 ENST00000334082.6:c.272C>T p.Ser91Phe p.S91F ENST00000334082 NM_004272.4 91 tCc/tTc 0 +HOXA11 UCSF GRCh37 7 27224621 27224621 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 51 134 0 ENST00000006015.3:c.143C>T p.Ser48Phe p.S48F ENST00000006015 NM_005523.5 48 tCc/tTc 0 +HOXA3 UCSF GRCh37 7 27147692 27147692 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 35 81 0 ENST00000317201.2:c.1174G>A p.Ala392Thr p.A392T ENST00000317201 NM_153631.2 392 Gcc/Acc 0 +HOXD3 UCSF GRCh37 2 177036434 177036434 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 75 45 146 0 ENST00000249440.3:c.731A>G p.Asn244Ser p.N244S ENST00000249440 NM_006898.4 244 aAc/aGc 0 +HOXD9 UCSF GRCh37 2 176988780 176988780 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 148 98 224 0 ENST00000249499.6:c.936G>A p.Arg312= p.R312= ENST00000249499 NM_014213.3 312 cgG/cgA 0 +HP1BP3 UCSF GRCh37 1 21097494 21097494 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 82 134 0 ENST00000312239.5:c.583G>A p.Glu195Lys p.E195K ENST00000312239 NM_016287.3 195 Gag/Aag 0 +HPD UCSF GRCh37 12 122281701 122281701 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 68 124 0 ENST00000289004.4:c.869C>T p.Ser290Phe p.S290F ENST00000289004 NM_002150.2 290 tCt/tTt 0 +HPN UCSF GRCh37 19 35556509 35556509 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 60 108 0 ENST00000262626.2:c.974C>T p.Ala325Val p.A325V ENST00000262626 NM_182983.2 325 gCt/gTt 0 +HS3ST5 UCSF GRCh37 6 114378655 114378655 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 61 143 0 ENST00000312719.5:c.807G>A p.Val269= p.V269= ENST00000312719 269 gtG/gtA 0 +HS6ST1 UCSF GRCh37 2 129026197 129026197 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 22 94 0 ENST00000259241.6:c.775C>T p.Leu259= p.L259= ENST00000259241 NM_004807.2 259 Ctg/Ttg 0 +HSD17B1 UCSF GRCh37 17 40706695 40706695 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 27 24 47 0 ENST00000585807.1:c.726C>T p.Leu242= p.L242= ENST00000585807 NM_000413.2 242 ctC/ctT 0 +HSD3B1 UCSF GRCh37 1 120057019 120057019 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 108 210 0 ENST00000369413.3:c.873G>A p.Met291Ile p.M291I ENST00000369413 291 atG/atA 0 +HSDL2 UCSF GRCh37 9 115179137 115179137 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 50 106 0 ENST00000398805.3:c.412C>T p.Pro138Ser p.P138S ENST00000398805 NM_032303.4 138 Cct/Tct 0 +HSF4 UCSF GRCh37 16 67202963 67202963 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 28 82 0 ENST00000264009.8:c.1213C>T p.Arg405Ter p.R405* ENST00000264009 NM_001040667.2 405 Cga/Tga 0 +HSPA1A UCSF GRCh37 6 31785229 31785229 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 41 121 0 ENST00000375651.5:c.1696G>A p.Asp566Asn p.D566N ENST00000375651 NM_005345.5 566 Gac/Aac 0 +HSPA2 UCSF GRCh37 14 65008270 65008270 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 54 112 0 ENST00000247207.6:c.703G>A p.Asp235Asn p.D235N ENST00000247207 NM_021979.3 235 Gac/Aac 0 +HSPA6 UCSF GRCh37 1 161495582 161495582 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 19 93 0 ENST00000309758.4:c.1134G>A p.Gln378= p.Q378= ENST00000309758 NM_002155.3 378 caG/caA 0 +HSPBAP1 UCSF GRCh37 3 122459361 122459361 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 100 236 0 ENST00000306103.2:c.1298G>A p.Arg433Lys p.R433K ENST00000306103 NM_024610.5 433 aGa/aAa 0 +HSPG2 UCSF GRCh37 1 22217131 22217131 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 64 164 0 ENST00000374695.3:c.301G>A p.Glu101Lys p.E101K ENST00000374695 NM_005529.5 101 Gag/Aag 0 +HTR3D UCSF GRCh37 3 183754189 183754189 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 50 102 0 ENST00000382489.3:c.407T>A p.Met136Lys p.M136K ENST00000382489 NM_001163646.1 136 aTg/aAg 0 +HYDIN UCSF GRCh37 16 70929894 70929894 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 286 56 310 0 ENST00000393567.2:c.9138C>T p.Thr3046= p.T3046= ENST00000393567 NM_001270974.1 3046 acC/acT 0 +HYDIN UCSF GRCh37 16 71113831 71113831 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 152 27 159 0 ENST00000393567.2:c.1695C>T p.Phe565= p.F565= ENST00000393567 NM_001270974.1 565 ttC/ttT 0 +IARS2 UCSF GRCh37 1 220267700 220267700 + 5_prime_UTR_variant 5'UTR SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 10 33 0 ENST00000366922.1:c.-75G>A *25* ENST00000366922 0 +IARS2 UCSF GRCh37 1 220315250 220315250 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 107 232 0 ENST00000366922.1:c.2304C>T p.His768= p.H768= ENST00000366922 768 caC/caT 0 +ICAM1 UCSF GRCh37 19 10395087 10395087 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 42 118 0 ENST00000264832.3:c.934G>A p.Ala312Thr p.A312T ENST00000264832 NM_000201.2 312 Gcg/Acg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 54 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFIT1B UCSF GRCh37 10 91143734 91143734 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 207 179 342 0 ENST00000371809.3:c.664C>T p.Leu222Phe p.L222F ENST00000371809 NM_001010987.2 222 Ctc/Ttc 0 +IFRD2 UCSF GRCh37 3 50326905 50326905 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 21 59 0 ENST00000417626.2:c.752G>A p.Ser251Asn p.S251N ENST00000417626 NM_006764.4 251 aGc/aAc 0 +IFT122 UCSF GRCh37 3 129197029 129197029 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 44 100 0 ENST00000348417.2:c.1318G>A p.Val440Met p.V440M ENST00000348417 NM_052989.2 440 Gtg/Atg 0 +IGF2BP1 UCSF GRCh37 17 47122362 47122362 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 66 205 0 ENST00000290341.3:c.1330C>T p.Pro444Ser p.P444S ENST00000290341 NM_006546.3 444 Ccc/Tcc 0 +IGF2R UCSF GRCh37 6 160493852 160493852 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 66 167 0 ENST00000356956.1:c.4626C>T p.Tyr1542= p.Y1542= ENST00000356956 NM_000876.2 1542 taC/taT 0 +IGF2R UCSF GRCh37 6 160467530 160467530 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 36 73 0 ENST00000356956.1:c.1904G>A p.Gly635Glu p.G635E ENST00000356956 NM_000876.2 635 gGg/gAg 0 +IGFN1 UCSF GRCh37 1 201185818 201185818 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 29 87 0 ENST00000295591.8:c.1012G>A p.Ala338Thr p.A338T ENST00000295591 338 Gct/Act 0 +IGHMBP2 UCSF GRCh37 11 68703919 68703919 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 65 121 0 ENST00000255078.3:c.1971G>A p.Gln657= p.Q657= ENST00000255078 NM_002180.2 657 caG/caA 0 +IGSF23 UCSF GRCh37 19 45127135 45127135 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 53 160 0 ENST00000402988.1:c.257G>A p.Ser86Asn p.S86N ENST00000402988 NM_001205280.1 86 aGt/aAt 0 +IGSF9 UCSF GRCh37 1 159898138 159898138 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 14 38 0 ENST00000368094.1:c.3040C>T p.Pro1014Ser p.P1014S ENST00000368094 NM_001135050.1 1014 Cct/Tct 0 +IK UCSF GRCh37 5 140037151 140037151 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 236 154 353 0 ENST00000417647.2:c.814C>T p.Leu272= p.L272= ENST00000417647 NM_006083.3 272 Ctg/Ttg 0 +IKBKB UCSF GRCh37 8 42174227 42174227 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 33 72 0 ENST00000520810.1:c.931-1G>A p.X311_splice ENST00000520810 NM_001556.2 0 +IKZF1 UCSF GRCh37 7 50444387 50444387 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 164 99 244 0 ENST00000331340.3:c.317G>A p.Gly106Glu p.G106E ENST00000331340 NM_006060.4 106 gGa/gAa 0 +IKZF5 UCSF GRCh37 10 124753424 124753424 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 91 193 0 ENST00000368886.5:c.1132C>T p.Leu378Phe p.L378F ENST00000368886 NM_001271840.1 378 Ctt/Ttt 0 +IL17RC UCSF GRCh37 3 9974706 9974706 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 10 23 0 ENST00000295981.3:c.1805G>A p.Gly602Asp p.G602D ENST00000295981 NM_153461.3 602 gGc/gAc 0 +IL20RB UCSF GRCh37 3 136710806 136710806 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 82 163 0 ENST00000329582.4:c.558G>A p.Gly186= p.G186= ENST00000329582 NM_144717.3 186 ggG/ggA 0 +ILF3 UCSF GRCh37 19 10793267 10793267 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 36 79 0 ENST00000590261.1:c.1435G>A p.Gly479Arg p.G479R ENST00000590261 479 Ggg/Agg 0 +IMP5 UCSF GRCh37 17 43924060 43924060 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 73 134 0 ENST00000329196.5:c.1788C>T p.Asp596= p.D596= ENST00000329196 NM_175882.2 596 gaC/gaT 0 +IMPG2 UCSF GRCh37 3 100994553 100994553 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 61 141 0 ENST00000193391.7:c.620C>T p.Ala207Val p.A207V ENST00000193391 NM_016247.3 207 gCc/gTc 0 +IMPG2 UCSF GRCh37 3 100961716 100961716 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 73 167 0 ENST00000193391.7:c.2838C>T p.Phe946= p.F946= ENST00000193391 NM_016247.3 946 ttC/ttT 0 +INADL UCSF GRCh37 1 62240978 62240978 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 168 117 276 0 ENST00000371158.2:c.821C>T p.Thr274Ile p.T274I ENST00000371158 NM_176877.2 274 aCt/aTt 0 +INO80D UCSF GRCh37 2 206921489 206921489 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0021 P18_Rec Untested WXS Illumina HiSeq 112 86 211 0 ENST00000403263.1:c.397C>T p.Pro133Ser p.P133S ENST00000403263 NM_017759.4 133 Cca/Tca 0 +INPP4A UCSF GRCh37 2 99136584 99136584 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 8 57 0 ENST00000074304.5:c.73G>A p.Val25Met p.V25M ENST00000074304 NM_001134224.1 25 Gtg/Atg 0 +INPP4A UCSF GRCh37 2 99170778 99170778 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 48 82 0 ENST00000074304.5:c.1407C>T p.Asn469= p.N469= ENST00000074304 NM_001134224.1 469 aaC/aaT 0 +INPP5F UCSF GRCh37 10 121579000 121579000 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 37 117 0 ENST00000361976.2:c.1887-1358G>A *629* ENST00000361976 NM_014937.3 0 +INPP5K UCSF GRCh37 17 1416790 1416790 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 165 114 231 0 ENST00000421807.2:c.218G>A p.Ser73Asn p.S73N ENST00000421807 NM_016532.3 73 aGc/aAc 0 +INTS10 UCSF GRCh37 8 19675133 19675133 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 7 8 15 0 ENST00000397977.3:c.85C>T p.Leu29= p.L29= ENST00000397977 NM_018142.2 29 Ctg/Ttg 0 +INTS3 UCSF GRCh37 1 153736307 153736307 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 14 42 0 ENST00000318967.2:c.1767-1G>A p.X589_splice ENST00000318967 NM_023015.3 0 +INTS3 UCSF GRCh37 1 153740288 153740288 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 63 109 0 ENST00000318967.2:c.2229C>T p.Pro743= p.P743= ENST00000318967 NM_023015.3 743 ccC/ccT 0 +INTS5 UCSF GRCh37 11 62414821 62414821 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 108 176 0 ENST00000330574.2:c.2731G>A p.Val911Met p.V911M ENST00000330574 NM_030628.1 911 Gtg/Atg 0 +IP6K3 UCSF GRCh37 6 33696027 33696027 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 37 84 0 ENST00000293756.4:c.250G>A p.Val84Ile p.V84I ENST00000293756 NM_054111.4 84 Gtt/Att 0 +IPO4 UCSF GRCh37 14 24656119 24656119 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 41 111 0 ENST00000354464.6:c.721C>T p.Pro241Ser p.P241S ENST00000354464 NM_024658.3 241 Ccc/Tcc 0 +IPO5 UCSF GRCh37 13 98654779 98654779 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 66 186 0 ENST00000357602.3:c.1167C>T p.Cys389= p.C389= ENST00000357602 389 tgC/tgT 0 +IQCB1 UCSF GRCh37 3 121544935 121544935 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 46 122 0 ENST00000310864.6:c.356G>A p.Gly119Glu p.G119E ENST00000310864 NM_001023570.2 119 gGg/gAg 0 +IQCG UCSF GRCh37 3 197619574 197619574 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 165 133 320 0 ENST00000265239.6:c.1020G>A p.Met340Ile p.M340I ENST00000265239 NM_032263.3 340 atG/atA 0 +IQCJ-SCHIP1 UCSF GRCh37 3 159606716 159606716 + synonymous_variant Silent SNP C C T snp132_rs2306063 P18_Rec Untested WXS Illumina HiSeq 121 93 201 0 ENST00000337808.6:c.1302C>T p.Leu434= p.L434= ENST00000337808 NM_001197107.1 434 ctC/ctT 0 +IREB2 UCSF GRCh37 15 78786575 78786575 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 224 125 301 0 ENST00000258886.8:c.2564G>A p.Arg855Lys p.R855K ENST00000258886 NM_004136.2 855 aGa/aAa 0 +IRF2 UCSF GRCh37 4 185350210 185350210 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 44 78 0 ENST00000393593.3:c.9G>A p.Val3= p.V3= ENST00000393593 NM_002199.3 3 gtG/gtA 0 +IRF2BP2 UCSF GRCh37 1 234743566 234743566 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 35 87 0 ENST00000366609.3:c.1081C>T p.Pro361Ser p.P361S ENST00000366609 NM_182972.2 361 Cca/Tca 0 +IRS4 UCSF GRCh37 X 107977198 107977198 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 166 159 0 ENST00000372129.2:c.2377C>T p.Pro793Ser p.P793S ENST00000372129 NM_003604.2 793 Ccc/Tcc 0 +IRX1 UCSF GRCh37 5 3600728 3600728 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 32 90 0 ENST00000302006.3:c.1318G>A p.Asp440Asn p.D440N ENST00000302006 NM_024337.3 440 Gac/Aac 0 +ITFG1 UCSF GRCh37 16 47409814 47409814 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 45 118 0 ENST00000320640.6:c.693C>T p.Thr231= p.T231= ENST00000320640 NM_030790.3 231 acC/acT 0 +ITGA5 UCSF GRCh37 12 54795811 54795811 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 51 131 0 ENST00000293379.4:c.2200G>A p.Gly734Ser p.G734S ENST00000293379 NM_002205.2 734 Ggc/Agc 0 +ITGA8 UCSF GRCh37 10 15647730 15647730 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 36 89 0 ENST00000378076.3:c.1963G>A p.Ala655Thr p.A655T ENST00000378076 NM_003638.1 655 Gct/Act 0 +ITGA8 UCSF GRCh37 10 15719614 15719614 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 239 126 185 0 ENST00000378076.3:c.653G>A p.Gly218Glu p.G218E ENST00000378076 NM_003638.1 218 gGa/gAa 0 +ITGAD UCSF GRCh37 16 31429662 31429662 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 56 115 0 ENST00000389202.2:c.2657C>T p.Thr886Ile p.T886I ENST00000389202 NM_005353.2 886 aCc/aTc 0 +ITGAL UCSF GRCh37 16 30500707 30500707 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 49 123 1 ENST00000356798.6:c.1213G>A p.Gly405Ser p.G405S ENST00000356798 NM_002209.2 405 Ggt/Agt 0 +ITGB3 UCSF GRCh37 17 45360902 45360902 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 46 121 0 ENST00000559488.1:c.348C>T p.Leu116= p.L116= ENST00000559488 NM_000212.2 116 ctC/ctT 0 +ITGB4 UCSF GRCh37 17 73739880 73739880 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 19 40 0 ENST00000200181.3:c.3049C>T p.Leu1017= p.L1017= ENST00000200181 NM_000213.3 1017 Ctg/Ttg 0 +ITGB4 UCSF GRCh37 17 73752517 73752517 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 41 112 0 ENST00000200181.3:c.4716G>A p.Leu1572= p.L1572= ENST00000200181 NM_000213.3 1572 ctG/ctA 0 +ITIH1 UCSF GRCh37 3 52812466 52812466 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 90 220 0 ENST00000273283.2:c.249G>A p.Arg83= p.R83= ENST00000273283 NM_002215.3 83 agG/agA 0 +ITPKC UCSF GRCh37 19 41224119 41224119 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 55 111 0 ENST00000263370.2:c.1079C>T p.Ala360Val p.A360V ENST00000263370 NM_025194.2 360 gCc/gTc 0 +ITPR1 UCSF GRCh37 3 4715049 4715049 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 580 120 296 0 ENST00000354582.6:c.2434C>T p.Pro812Ser p.P812S ENST00000354582 812 Ccc/Tcc 0 +ITPR1 UCSF GRCh37 3 4722322 4722322 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 292 56 135 0 ENST00000354582.6:c.3053C>T p.Thr1018Ile p.T1018I ENST00000354582 1018 aCt/aTt 0 +ITPR1 UCSF GRCh37 3 4681123 4681123 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 355 76 154 0 ENST00000354582.6:c.335G>A p.Gly112Glu p.G112E ENST00000354582 112 gGg/gAg 0 +ITPR1 UCSF GRCh37 3 4808213 4808213 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 428 88 233 0 ENST00000354582.6:c.5500-1G>A p.X1834_splice ENST00000354582 0 +ITPR1 UCSF GRCh37 3 4829658 4829658 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 551 132 263 0 ENST00000354582.6:c.6598C>T p.Gln2200Ter p.Q2200* ENST00000354582 2200 Cag/Tag 0 +ITPR1 UCSF GRCh37 3 4817088 4817088 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 629 140 305 0 ENST00000354582.6:c.6097C>T p.Leu2033= p.L2033= ENST00000354582 2033 Ctg/Ttg 0 +IWS1 UCSF GRCh37 2 128238734 128238734 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 70 157 0 ENST00000295321.4:c.2346G>A p.Lys782= p.K782= ENST00000295321 NM_017969.2 782 aaG/aaA 0 +JAG1 UCSF GRCh37 20 10620400 10620400 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 53 139 0 ENST00000254958.5:c.3403C>T p.Pro1135Ser p.P1135S ENST00000254958 NM_000214.2 1135 Ccc/Tcc 0 +JAKMIP2 UCSF GRCh37 5 147030033 147030033 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 60 146 0 ENST00000265272.5:c.705G>A p.Gln235= p.Q235= ENST00000265272 NM_014790.4 235 caG/caA 0 +JKAMP UCSF GRCh37 14 59970668 59970668 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 173 135 272 0 ENST00000261247.9:c.814G>A p.Asp272Asn p.D272N ENST00000261247 NM_001098625.1 272 Gat/Aat 0 +JUB UCSF GRCh37 14 23443256 23443256 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 144 103 249 0 ENST00000262713.2:c.1491G>A p.Glu497= p.E497= ENST00000262713 NM_032876.4 497 gaG/gaA 0 +JUNB UCSF GRCh37 19 12902742 12902742 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 28 47 0 ENST00000302754.4:c.157C>T p.Pro53Ser p.P53S ENST00000302754 NM_002229.2 53 Cct/Tct 0 +KANK1 UCSF GRCh37 9 713345 713345 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 108 229 0 ENST00000382297.2:c.2579G>A p.Gly860Asp p.G860D ENST00000382297 NM_001256877.1 860 gGc/gAc 0 +KANK4 UCSF GRCh37 1 62740568 62740568 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 97 194 0 ENST00000371153.4:c.208C>T p.Pro70Ser p.P70S ENST00000371153 NM_181712.4 70 Ccc/Tcc 0 +KAT6B UCSF GRCh37 10 76602646 76602646 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 103 246 0 ENST00000287239.4:c.31G>A p.Glu11Lys p.E11K ENST00000287239 NM_001256468.1 11 Gag/Aag 0 +KAZN UCSF GRCh37 1 15382767 15382767 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 26 57 0 ENST00000376030.2:c.907G>A p.Asp303Asn p.D303N ENST00000376030 NM_201628.2 303 Gac/Aac 0 +KBTBD10 UCSF GRCh37 2 170382119 170382119 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 80 197 0 ENST00000284669.1:c.1734G>A p.Trp578Ter p.W578* ENST00000284669 NM_006063.2 578 tgG/tgA 0 +KBTBD10 UCSF GRCh37 2 170374757 170374757 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 73 149 0 ENST00000284669.1:c.1434G>A p.Leu478= p.L478= ENST00000284669 NM_006063.2 478 ctG/ctA 0 +KBTBD6 UCSF GRCh37 13 41705456 41705456 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 92 239 0 ENST00000379485.1:c.1192G>A p.Ala398Thr p.A398T ENST00000379485 NM_152903.4 398 Gct/Act 0 +KCNA4 UCSF GRCh37 11 30033280 30033280 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 91 203 0 ENST00000328224.6:c.946G>A p.Val316Ile p.V316I ENST00000328224 NM_002233.3 316 Gtc/Atc 0 +KCND2 UCSF GRCh37 7 119914851 119914851 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 117 237 0 ENST00000331113.4:c.165G>A p.Trp55Ter p.W55* ENST00000331113 NM_012281.2 55 tgG/tgA 0 +KCND3 UCSF GRCh37 1 112524839 112524839 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 33 101 0 ENST00000315987.2:c.510G>A p.Trp170Ter p.W170* ENST00000315987 NM_004980.4 170 tgG/tgA 0 +KCNF1 UCSF GRCh37 2 11053062 11053062 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 24 82 0 ENST00000295082.1:c.510G>A p.Lys170= p.K170= ENST00000295082 NM_002236.4 170 aaG/aaA 0 +KCNH1 UCSF GRCh37 1 210857328 210857328 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 38 86 0 ENST00000271751.4:c.2265G>A p.Glu755= p.E755= ENST00000271751 755 gaG/gaA 0 +KCNH6 UCSF GRCh37 17 61607784 61607784 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 59 132 0 ENST00000583023.1:c.556C>T p.Leu186Phe p.L186F ENST00000583023 NM_030779.3 186 Ctc/Ttc 0 +KCNH8 UCSF GRCh37 3 19295191 19295191 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 104 236 0 ENST00000328405.2:c.122C>T p.Pro41Leu p.P41L ENST00000328405 NM_144633.2 41 cCc/cTc 0 +KCNJ16 UCSF GRCh37 17 68129012 68129012 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 182 114 274 0 ENST00000283936.1:c.784C>T p.Pro262Ser p.P262S ENST00000283936 NM_018658.2 262 Cct/Tct 0 +KCNJ3 UCSF GRCh37 2 155711415 155711415 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 75 196 0 ENST00000295101.2:c.1096C>T p.Leu366Phe p.L366F ENST00000295101 NM_002239.3 366 Ctc/Ttc 0 +KCNK1 UCSF GRCh37 1 233802420 233802420 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 39 100 0 ENST00000366621.3:c.435C>T p.Thr145= p.T145= ENST00000366621 NM_002245.3 145 acC/acT 0 +KCNK13 UCSF GRCh37 14 90650846 90650846 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 90 208 0 ENST00000282146.4:c.726C>T p.Asp242= p.D242= ENST00000282146 NM_022054.3 242 gaC/gaT 0 +KCNK16 UCSF GRCh37 6 39282863 39282863 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 61 142 0 ENST00000373229.5:c.845G>A p.Arg282Lys p.R282K ENST00000373229 NM_032115.3 282 aGa/aAa 0 +KCNK17 UCSF GRCh37 6 39267491 39267491 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 76 139 0 ENST00000373231.4:c.711C>T p.Tyr237= p.Y237= ENST00000373231 NM_031460.3 237 taC/taT 0 +KCNK4 UCSF GRCh37 11 64065096 64065096 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 86 57 131 0 ENST00000394525.2:c.632C>T p.Thr211Ile p.T211I ENST00000394525 211 aCc/aTc 0 +KCNK5 UCSF GRCh37 6 39162060 39162060 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 75 145 0 ENST00000359534.3:c.519C>T p.Val173= p.V173= ENST00000359534 NM_003740.3 173 gtC/gtT 0 +KCNMA1 UCSF GRCh37 10 79163778 79163778 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 54 106 0 ENST00000286628.8:c.382G>A p.Ala128Thr p.A128T ENST00000286628 NM_001161352.1 128 Gcc/Acc 0 +KCNT1 UCSF GRCh37 9 138645788 138645788 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 27 64 1 ENST00000488444.2:c.383G>A p.Gly128Asp p.G128D ENST00000488444 128 gGc/gAc 0 +KCNT1 UCSF GRCh37 9 138649046 138649046 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 44 119 0 ENST00000488444.2:c.588G>A p.Glu196= p.E196= ENST00000488444 196 gaG/gaA 0 +KCNT1 UCSF GRCh37 9 138678090 138678090 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 9 18 0 ENST00000488444.2:c.3162G>A p.Val1054= p.V1054= ENST00000488444 1054 gtG/gtA 0 +KCNU1 UCSF GRCh37 8 36691074 36691074 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 229 201 371 0 ENST00000399881.3:c.1109C>T p.Thr370Ile p.T370I ENST00000399881 NM_001031836.2 370 aCc/aTc 0 +KDM2B UCSF GRCh37 12 122016746 122016746 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 42 68 0 ENST00000377071.4:c.232C>T p.Leu78= p.L78= ENST00000377071 NM_032590.4 78 Ctg/Ttg 0 +KDM3B UCSF GRCh37 5 137754882 137754882 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 54 131 0 ENST00000314358.5:c.3676G>A p.Ala1226Thr p.A1226T ENST00000314358 NM_016604.3 1226 Gca/Aca 0 +KDM3B UCSF GRCh37 5 137767249 137767249 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 74 212 0 ENST00000314358.5:c.5205+1G>A p.X1735_splice ENST00000314358 NM_016604.3 0 +KERA UCSF GRCh37 12 91445287 91445287 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 52 134 0 ENST00000266719.3:c.895G>A p.Val299Ile p.V299I ENST00000266719 NM_007035.3 299 Gtc/Atc 0 +KIAA0100 UCSF GRCh37 17 26945953 26945953 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 57 105 0 ENST00000528896.2:c.5679G>A p.Lys1893= p.K1893= ENST00000528896 NM_014680.3 1893 aaG/aaA 0 +KIAA0100 UCSF GRCh37 17 26950785 26950785 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 83 171 0 ENST00000528896.2:c.4952G>A p.Trp1651Ter p.W1651* ENST00000528896 NM_014680.3 1651 tGg/tAg 0 +KIAA0100 UCSF GRCh37 17 26960944 26960944 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 65 137 0 ENST00000528896.2:c.3231G>A p.Met1077Ile p.M1077I ENST00000528896 NM_014680.3 1077 atG/atA 0 +KIAA0141 UCSF GRCh37 5 141305047 141305047 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 67 162 0 ENST00000194118.4:c.219G>A p.Met73Ile p.M73I ENST00000194118 73 atG/atA 0 +KIAA0196 UCSF GRCh37 8 126093945 126093945 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 119 60 185 0 ENST00000318410.7:c.476G>A p.Gly159Glu p.G159E ENST00000318410 NM_014846.3 159 gGa/gAa 0 +KIAA0226 UCSF GRCh37 3 197421334 197421334 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 77 177 0 ENST00000296343.5:c.1596C>T p.Ile532= p.I532= ENST00000296343 NM_014687.1 532 atC/atT 0 +KIAA0232 UCSF GRCh37 4 6863304 6863304 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 89 163 0 ENST00000307659.5:c.1195G>A p.Glu399Lys p.E399K ENST00000307659 NM_014743.2 399 Gag/Aag 0 +KIAA0240 UCSF GRCh37 6 42797076 42797076 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 188 157 330 0 ENST00000314073.5:c.1005G>A p.Gln335= p.Q335= ENST00000314073 335 caG/caA 0 +KIAA0284 UCSF GRCh37 14 105350247 105350247 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 17 52 0 ENST00000414716.3:c.1131G>A p.Leu377= p.L377= ENST00000414716 NM_001112726.2 377 ttG/ttA 0 +KIAA0415 UCSF GRCh37 7 4821359 4821359 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 28 78 0 ENST00000348624.4:c.340C>T p.Leu114= p.L114= ENST00000348624 NM_014855.2 114 Ctg/Ttg 0 +KIAA0430 UCSF GRCh37 16 15710946 15710946 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 205 77 188 0 ENST00000396368.3:c.3040C>T p.Leu1014Phe p.L1014F ENST00000396368 NM_001184998.1 1014 Ctt/Ttt 0 +KIAA0564 UCSF GRCh37 13 42295652 42295652 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 95 156 0 ENST00000379310.3:c.2818C>T p.Leu940Phe p.L940F ENST00000379310 NM_015058.1 940 Ctc/Ttc 0 +KIAA0889 UCSF GRCh37 20 35444374 35444374 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 27 70 0 ENST00000237536.4:c.1471C>T p.Pro491Ser p.P491S ENST00000237536 NM_080627.2 491 Cct/Tct 0 +KIAA0922 UCSF GRCh37 4 154512332 154512332 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 109 267 0 ENST00000409663.3:c.1795C>T p.Leu599Phe p.L599F ENST00000409663 NM_015196.3 599 Ctt/Ttt 0 +KIAA0947 UCSF GRCh37 5 5464975 5464975 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 40 69 0 ENST00000296564.7:c.5528G>A p.Arg1843Lys p.R1843K ENST00000296564 NM_015325.2 1843 aGa/aAa 0 +KIAA1211 UCSF GRCh37 4 57190331 57190331 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 36 120 0 ENST00000264229.6:c.3440C>T p.Ser1147Phe p.S1147F ENST00000264229 NM_020722.1 1147 tCc/tTc 0 +KIAA1211 UCSF GRCh37 4 57182328 57182328 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 20 73 0 ENST00000264229.6:c.2660G>A p.Gly887Glu p.G887E ENST00000264229 NM_020722.1 887 gGg/gAg 0 +KIAA1217 UCSF GRCh37 10 24813287 24813287 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 63 110 0 ENST00000376454.3:c.2492C>T p.Ala831Val p.A831V ENST00000376454 NM_019590.3 831 gCa/gTa 0 +KIAA1217 UCSF GRCh37 10 24813626 24813626 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 141 41 98 0 ENST00000376454.3:c.2831C>T p.Ala944Val p.A944V ENST00000376454 NM_019590.3 944 gCc/gTc 0 +KIAA1217 UCSF GRCh37 10 24831845 24831845 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 59 104 0 ENST00000376454.3:c.3646C>T p.Pro1216Ser p.P1216S ENST00000376454 NM_019590.3 1216 Cct/Tct 0 +KIAA1217 UCSF GRCh37 10 24834887 24834887 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 279 149 263 0 ENST00000376454.3:c.5466C>T p.Ser1822= p.S1822= ENST00000376454 NM_019590.3 1822 agC/agT 0 +KIAA1310 UCSF GRCh37 2 97267863 97267863 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 26 57 0 ENST00000431828.1:c.2472C>T p.Asn824= p.N824= ENST00000431828 824 aaC/aaT 0 +KIAA1370 UCSF GRCh37 15 52903407 52903407 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 132 341 0 ENST00000261844.7:c.450C>T p.Val150= p.V150= ENST00000261844 NM_019600.2 150 gtC/gtT 0 +KIAA1383 UCSF GRCh37 1 232942673 232942673 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 149 126 213 0 ENST00000418460.1:c.1904G>A p.Gly635Glu p.G635E ENST00000418460 NM_019090.2 635 gGg/gAg 0 +KIAA1468 UCSF GRCh37 18 59942649 59942649 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 34 81 0 ENST00000398130.2:c.2910G>A p.Trp970Ter p.W970* ENST00000398130 NM_020854.3 970 tgG/tgA 0 +KIAA1614 UCSF GRCh37 1 180885292 180885292 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 18 52 0 ENST00000367588.4:c.53G>A p.Gly18Glu p.G18E ENST00000367588 NM_020950.1 18 gGg/gAg 0 +KIAA1671 UCSF GRCh37 22 25424711 25424711 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 5 17 28 0 ENST00000358431.3:c.745G>A p.Glu249Lys p.E249K ENST00000358431 NM_001145206.1 249 Gag/Aag 0 +KIAA1958 UCSF GRCh37 9 115408050 115408050 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 81 182 0 ENST00000337530.6:c.1292G>A p.Trp431Ter p.W431* ENST00000337530 NM_001287038.1 431 tGg/tAg 0 +KIAA2018 UCSF GRCh37 3 113377351 113377351 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 167 107 268 0 ENST00000316407.4:c.3178G>A p.Asp1060Asn p.D1060N ENST00000316407 NM_001009899.2 1060 Gat/Aat 0 +KIAA2018 UCSF GRCh37 3 113380149 113380149 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 143 96 227 0 ENST00000316407.4:c.380G>A p.Gly127Glu p.G127E ENST00000316407 NM_001009899.2 127 gGa/gAa 0 +KIF12 UCSF GRCh37 9 116854152 116854152 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 41 0 ENST00000374118.3:c.1531C>T p.Pro511Ser p.P511S ENST00000374118 NM_138424.1 511 Cct/Tct 0 +KIF13A UCSF GRCh37 6 17817358 17817358 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 70 105 0 ENST00000259711.6:c.1893C>T p.Leu631= p.L631= ENST00000259711 NM_022113.5 631 ctC/ctT 0 +KIF13A UCSF GRCh37 6 17799560 17799560 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 69 137 0 ENST00000259711.6:c.2727C>T p.Asp909= p.D909= ENST00000259711 NM_022113.5 909 gaC/gaT 0 +KIF15 UCSF GRCh37 3 44868999 44868999 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 43 119 0 ENST00000326047.4:c.2835G>A p.Glu945= p.E945= ENST00000326047 NM_020242.2 945 gaG/gaA 0 +KIF19 UCSF GRCh37 17 72351387 72351387 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 29 77 0 ENST00000389916.4:c.2933G>A p.Arg978His p.R978H ENST00000389916 NM_153209.3 978 cGt/cAt 0 +KIF1B UCSF GRCh37 1 10386370 10386370 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 71 151 0 ENST00000377086.1:c.2877G>A p.Gly959= p.G959= ENST00000377086 959 ggG/ggA 0 +KIF1B UCSF GRCh37 1 10402188 10402188 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 187 133 312 0 ENST00000377086.1:c.3594G>A p.Gln1198= p.Q1198= ENST00000377086 1198 caG/caA 0 +KIF21B UCSF GRCh37 1 200959124 200959124 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 32 91 0 ENST00000422435.2:c.3078C>T p.Ser1026= p.S1026= ENST00000422435 NM_001252100.1 1026 tcC/tcT 0 +KIF26A UCSF GRCh37 14 104639339 104639339 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 30 19 51 0 ENST00000423312.2:c.1446G>A p.Lys482= p.K482= ENST00000423312 NM_015656.1 482 aaG/aaA 0 +KIF3B UCSF GRCh37 20 30919053 30919053 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 69 166 0 ENST00000375712.3:c.2175C>T p.Ser725= p.S725= ENST00000375712 NM_004798.3 725 tcC/tcT 0 +KIF5B UCSF GRCh37 10 32321645 32321645 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 79 182 0 ENST00000302418.4:c.1363G>A p.Asp455Asn p.D455N ENST00000302418 NM_004521.2 455 Gat/Aat 0 +KIF5B UCSF GRCh37 10 32311839 32311839 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 87 192 0 ENST00000302418.4:c.1851G>A p.Glu617= p.E617= ENST00000302418 NM_004521.2 617 gaG/gaA 0 +KIFC3 UCSF GRCh37 16 57793698 57793698 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 7 19 0 ENST00000379655.4:c.2418C>T p.Ala806= p.A806= ENST00000379655 NM_005550.3 806 gcC/gcT 0 +KIRREL3 UCSF GRCh37 11 126333116 126333116 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 32 70 0 ENST00000525144.2:c.678G>A p.Val226= p.V226= ENST00000525144 NM_032531.3 226 gtG/gtA 0 +KLF17 UCSF GRCh37 1 44595450 44595450 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 48 133 0 ENST00000372299.3:c.507G>A p.Met169Ile p.M169I ENST00000372299 NM_173484.3 169 atG/atA 0 +KLF6 UCSF GRCh37 10 3824180 3824180 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 245 159 227 0 ENST00000497571.1:c.329G>A p.Ser110Asn p.S110N ENST00000497571 NM_001300.5 110 aGc/aAc 0 +KLHDC10 UCSF GRCh37 7 129762040 129762040 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 186 215 0 ENST00000335420.5:c.777G>A p.Glu259= p.E259= ENST00000335420 NM_014997.3 259 gaG/gaA 0 +KLHDC8B UCSF GRCh37 3 49211804 49211804 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 56 157 0 ENST00000332780.2:c.509C>T p.Thr170Ile p.T170I ENST00000332780 NM_173546.2 170 aCc/aTc 0 +KLHL17 UCSF GRCh37 1 899356 899356 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 80 134 0 ENST00000338591.3:c.1412C>T p.Thr471Ile p.T471I ENST00000338591 NM_198317.2 471 aCc/aTc 0 +KLHL17 UCSF GRCh37 1 898853 898853 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 25 54 0 ENST00000338591.3:c.1324G>A p.Gly442Ser p.G442S ENST00000338591 NM_198317.2 442 Ggc/Agc 0 +KLHL17 UCSF GRCh37 1 897130 897130 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 15 63 0 ENST00000338591.3:c.489G>A p.Gln163= p.Q163= ENST00000338591 NM_198317.2 163 caG/caA 0 +KLHL21 UCSF GRCh37 1 6653605 6653605 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 44 31 85 0 ENST00000377658.4:c.1614C>T p.Arg538= p.R538= ENST00000377658 NM_014851.2 538 cgC/cgT 0 +KLHL7 UCSF GRCh37 7 23205492 23205492 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 66 156 0 ENST00000339077.5:c.1112C>A p.Pro371His p.P371H ENST00000339077 NM_001031710.2 371 cCt/cAt 0 +KLHL8 UCSF GRCh37 4 88106529 88106529 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 163 135 256 0 ENST00000273963.5:c.639C>T p.Leu213= p.L213= ENST00000273963 NM_020803.3 213 ctC/ctT 0 +KLK10 UCSF GRCh37 19 51519265 51519265 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 6 11 0 ENST00000309958.3:c.417G>A p.Met139Ile p.M139I ENST00000309958 NM_002776.4 139 atG/atA 0 +KLK12 UCSF GRCh37 19 51534051 51534051 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 68 139 0 ENST00000319590.4:c.584C>T p.Ala195Val p.A195V ENST00000319590 NM_145894.1 195 gCc/gTc 0 +KPNA3 UCSF GRCh37 13 50306749 50306749 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 68 190 0 ENST00000261667.3:c.279G>A p.Gln93= p.Q93= ENST00000261667 NM_002267.3 93 caG/caA 0 +KPRP UCSF GRCh37 1 152733154 152733154 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 44 96 0 ENST00000606109.1:c.1090G>A p.Gly364Ser p.G364S ENST00000606109 364 Ggc/Agc 0 +KREMEN1 UCSF GRCh37 22 29490366 29490366 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 68 8 141 0 ENST00000407188.1:c.212A>C p.Tyr71Ser p.Y71S ENST00000407188 71 tAc/tCc 0 +KRT12 UCSF GRCh37 17 39019559 39019559 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 30 26 64 0 ENST00000251643.4:c.1132G>A p.Gly378Ser p.G378S ENST00000251643 NM_000223.3 378 Ggc/Agc 0 +KRT17 UCSF GRCh37 17 39777949 39777949 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 98 171 0 ENST00000311208.8:c.730G>A p.Ala244Thr p.A244T ENST00000311208 NM_000422.2 244 Gcc/Acc 0 +KRT23 UCSF GRCh37 17 39081672 39081672 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 60 154 0 ENST00000209718.3:c.1076G>A p.Gly359Asp p.G359D ENST00000209718 NM_015515.3 359 gGc/gAc 0 +KRTAP10-3 UCSF GRCh37 21 45977945 45977945 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.005,1000g2011may_all_0.0170,snp132_rs13047815 P18_Rec Untested WXS Illumina HiSeq 42 29 66 0 ENST00000391620.1:c.654G>A p.Lys218= p.K218= ENST00000391620 NM_198696.2 218 aaG/aaA 0 +KRTAP4-7 UCSF GRCh37 17 39240848 39240848 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 49 96 0 ENST00000391417.4:c.390C>T p.Cys130= p.C130= ENST00000391417 NM_033061.3 130 tgC/tgT 0 +KRTCAP3 UCSF GRCh37 2 27666821 27666821 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 56 96 0 ENST00000288873.3:c.621G>A p.Glu207= p.E207= ENST00000288873 NM_173853.3 207 gaG/gaA 0 +KSR2 UCSF GRCh37 12 118199019 118199019 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 56 91 0 ENST00000339824.5:c.783G>A p.Pro261= p.P261= ENST00000339824 261 ccG/ccA 0 +KTI12 UCSF GRCh37 1 52498937 52498937 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 59 151 0 ENST00000371614.1:c.497C>T p.Ala166Val p.A166V ENST00000371614 NM_138417.2 166 gCc/gTc 0 +LAG3 UCSF GRCh37 12 6882393 6882393 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 62 104 0 ENST00000203629.2:c.94G>A p.Val32Met p.V32M ENST00000203629 NM_002286.5 32 Gtg/Atg 0 +LAIR2 UCSF GRCh37 19 55021774 55021774 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 76 220 0 ENST00000301202.2:c.454C>T p.Pro152Ser p.P152S ENST00000301202 NM_002288.4 152 Cca/Tca 0 +LAMA3 UCSF GRCh37 18 21529802 21529802 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 56 145 0 ENST00000313654.9:c.9425C>T p.Ser3142Phe p.S3142F ENST00000313654 NM_198129.1 3142 tCt/tTt 0 +LAMA5 UCSF GRCh37 20 60909396 60909396 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 17 0 ENST00000252999.3:c.2585C>T p.Pro862Leu p.P862L ENST00000252999 NM_005560.4 862 cCt/cTt 0 +LAMB1 UCSF GRCh37 7 107599749 107599749 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 131 92 212 0 ENST00000222399.6:c.2635G>A p.Val879Met p.V879M ENST00000222399 NM_002291.2 879 Gtg/Atg 0 +LAMB4 UCSF GRCh37 7 107696233 107696233 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 53 131 0 ENST00000205386.4:c.3599C>T p.Ala1200Val p.A1200V ENST00000205386 1200 gCt/gTt 0 +LAMB4 UCSF GRCh37 7 107708557 107708557 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 93 164 0 ENST00000205386.4:c.2350C>T p.Leu784Phe p.L784F ENST00000205386 784 Ctt/Ttt 0 +LAMTOR2 UCSF GRCh37 1 156025217 156025217 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 59 121 0 ENST00000368305.4:c.231+1G>A p.X77_splice ENST00000368305 NM_014017.3 0 +LANCL2 UCSF GRCh37 7 55467677 55467677 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 120 264 0 ENST00000254770.2:c.558C>T p.Val186= p.V186= ENST00000254770 NM_018697.3 186 gtC/gtT 0 +LARS2 UCSF GRCh37 3 45518014 45518014 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 75 187 0 ENST00000265537.3:c.913G>A p.Ala305Thr p.A305T ENST00000265537 NM_015340.3 305 Gcc/Acc 0 +LARS2 UCSF GRCh37 3 45561725 45561725 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 110 80 174 0 ENST00000265537.3:c.2229C>T p.Phe743= p.F743= ENST00000265537 NM_015340.3 743 ttC/ttT 0 +LBP UCSF GRCh37 20 37005267 37005267 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 171 114 271 0 ENST00000217407.2:c.1402G>A p.Asp468Asn p.D468N ENST00000217407 NM_004139.3 468 Gac/Aac 0 +LCA5 UCSF GRCh37 6 80198823 80198823 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 105 208 0 ENST00000369846.4:c.1209G>A p.Gln403= p.Q403= ENST00000369846 NM_001122769.2 403 caG/caA 0 +LCE1B UCSF GRCh37 1 152785227 152785227 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 45 118 0 ENST00000360090.3:c.305G>A p.Gly102Asp p.G102D ENST00000360090 NM_178349.1 102 gGc/gAc 0 +LCORL UCSF GRCh37 4 17847453 17847453 + downstream_gene_variant 3'Flank SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 154 114 230 0 ENST00000251496 NM_022346.4 0 +LCT UCSF GRCh37 2 136594109 136594109 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 140 83 215 0 ENST00000264162.2:c.631G>T p.Ala211Ser p.A211S ENST00000264162 NM_002299.2 211 Gct/Tct 0 +LETM1 UCSF GRCh37 4 1823919 1823919 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 58 112 0 ENST00000302787.2:c.1597G>A p.Glu533Lys p.E533K ENST00000302787 NM_012318.2 533 Gag/Aag 0 +LGALS4 UCSF GRCh37 19 39297145 39297145 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 68 139 0 ENST00000307751.4:c.430C>T p.Leu144Phe p.L144F ENST00000307751 NM_006149.3 144 Ctt/Ttt 0 +LGALS9C UCSF GRCh37 17 18392297 18392297 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 22 81 0 ENST00000328114.6:c.487C>T p.Pro163Ser p.P163S ENST00000328114 NM_001040078.2 163 Ccg/Tcg 0 +LILRA6 UCSF GRCh37 19 54744315 54744315 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 246 75 304 0 ENST00000396365.2:c.1093C>T p.Pro365Ser p.P365S ENST00000396365 NM_024318.2 365 Cca/Tca 0 +LILRB1 UCSF GRCh37 19 55148046 55148046 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 54 150 0 ENST00000324602.7:c.1755G>A p.Gly585= p.G585= ENST00000324602 NM_001278399.1 585 ggG/ggA 0 +LILRB5 UCSF GRCh37 19 54756405 54756405 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 37 89 0 ENST00000449561.2:c.1482C>T p.Phe494= p.F494= ENST00000449561 494 ttC/ttT 0 +LIMCH1 UCSF GRCh37 4 41652573 41652573 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 53 116 0 ENST00000313860.7:c.1829G>A p.Gly610Asp p.G610D ENST00000313860 NM_014988.2 610 gGt/gAt 0 +LIMK1 UCSF GRCh37 7 73520545 73520545 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 50 154 0 ENST00000336180.2:c.853G>A p.Gly285Ser p.G285S ENST00000336180 NM_002314.3 285 Ggc/Agc 0 +LINGO3 UCSF GRCh37 19 2291415 2291415 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 23 74 0 ENST00000585527.1:c.361G>A p.Val121Ile p.V121I ENST00000585527 121 Gtc/Atc 0 +LIPH UCSF GRCh37 3 185252808 185252808 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 193 134 333 0 ENST00000296252.4:c.162A>G p.Ala54= p.A54= ENST00000296252 NM_139248.2 54 gcA/gcG 0 +LMCD1 UCSF GRCh37 3 8607163 8607163 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 233 64 145 0 ENST00000157600.3:c.769G>A p.Val257Ile p.V257I ENST00000157600 NM_014583.3 257 Gtc/Atc 0 +LMNA UCSF GRCh37 1 156105024 156105024 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 25 68 0 ENST00000368300.4:c.857G>A p.Gly286Glu p.G286E ENST00000368300 NM_170707.3 286 gGg/gAg 0 +LMO7 UCSF GRCh37 13 76379635 76379635 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 156 104 262 0 ENST00000465261.2:c.236G>A p.Gly79Asp p.G79D ENST00000465261 NM_015842.2 79 gGc/gAc 0 +LMO7 UCSF GRCh37 13 76407286 76407286 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 187 162 374 0 ENST00000465261.2:c.2350G>A p.Ala784Thr p.A784T ENST00000465261 NM_015842.2 784 Gca/Aca 0 +LMOD3 UCSF GRCh37 3 69168785 69168785 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 198 154 353 0 ENST00000420581.2:c.721C>T p.Leu241= p.L241= ENST00000420581 NM_198271.3 241 Ctg/Ttg 0 +LMTK2 UCSF GRCh37 7 97770709 97770709 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 86 193 0 ENST00000297293.5:c.232G>A p.Glu78Lys p.E78K ENST00000297293 NM_014916.3 78 Gaa/Aaa 0 +LMTK3 UCSF GRCh37 19 49001311 49001311 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 85 174 0 ENST00000600059.1:c.3015G>A p.Glu1005= p.E1005= ENST00000600059 1005 gaG/gaA 0 +LNPEP UCSF GRCh37 5 96362436 96362436 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 99 175 0 ENST00000231368.5:c.2839G>A p.Glu947Lys p.E947K ENST00000231368 NM_005575.2 947 Gag/Aag 0 +LONP1 UCSF GRCh37 19 5711911 5711911 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 53 88 0 ENST00000360614.3:c.741G>A p.Glu247= p.E247= ENST00000360614 NM_004793.3 247 gaG/gaA 0 +LPA UCSF GRCh37 6 161022079 161022079 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 65 195 0 ENST00000316300.5:c.2997G>A p.Trp999Ter p.W999* ENST00000316300 999 tgG/tgA 0 +LPHN2 UCSF GRCh37 1 82436047 82436047 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 125 85 220 0 ENST00000370717.2:c.2771C>T p.Ala924Val p.A924V ENST00000370717 924 gCt/gTt 0 +LPHN3 UCSF GRCh37 4 62598985 62598985 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 195 136 317 0 ENST00000514591.1:c.908C>T p.Thr303Ile p.T303I ENST00000514591 303 aCt/aTt 0 +LPO UCSF GRCh37 17 56345285 56345285 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 44 155 0 ENST00000262290.4:c.2069C>T p.Pro690Leu p.P690L ENST00000262290 NM_006151.2 690 cCc/cTc 0 +LRCH1 UCSF GRCh37 13 47262035 47262035 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 48 157 0 ENST00000389798.3:c.871G>A p.Ala291Thr p.A291T ENST00000389798 NM_015116.2 291 Gca/Aca 0 +LRFN4 UCSF GRCh37 11 66625310 66625310 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 19 59 0 ENST00000309602.4:c.95C>T p.Thr32Ile p.T32I ENST00000309602 NM_024036.4 32 aCc/aTc 0 +LRG1 UCSF GRCh37 19 4538924 4538924 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 38 101 0 ENST00000306390.6:c.72C>T p.Phe24= p.F24= ENST00000306390 NM_052972.2 24 ttC/ttT 0 +LRGUK UCSF GRCh37 7 133848209 133848209 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 87 166 0 ENST00000285928.2:c.856G>A p.Asp286Asn p.D286N ENST00000285928 NM_144648.1 286 Gat/Aat 0 +LRIT1 UCSF GRCh37 10 85994012 85994012 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 80 173 0 ENST00000372105.3:c.712C>T p.Leu238= p.L238= ENST00000372105 NM_015613.2 238 Ctg/Ttg 0 +LRRC15 UCSF GRCh37 3 194081183 194081183 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 155 122 248 0 ENST00000347624.3:c.590G>A p.Gly197Asp p.G197D ENST00000347624 NM_130830.4 197 gGc/gAc 0 +LRRC16B UCSF GRCh37 14 24534907 24534907 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 62 114 0 ENST00000342740.5:c.3473C>T p.Ala1158Val p.A1158V ENST00000342740 NM_138360.3 1158 gCc/gTc 0 +LRRC17 UCSF GRCh37 7 102584853 102584853 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 134 101 212 0 ENST00000339431.4:c.1125C>T p.Gly375= p.G375= ENST00000339431 NM_001031692.2 375 ggC/ggT 0 +LRRC25 UCSF GRCh37 19 18507245 18507245 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 21 84 0 ENST00000339007.3:c.529C>T p.Leu177Phe p.L177F ENST00000339007 NM_145256.2 177 Ctt/Ttt 0 +LRRC36 UCSF GRCh37 16 67400959 67400959 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 93 194 0 ENST00000329956.6:c.794C>T p.Ser265Phe p.S265F ENST00000329956 NM_018296.5 265 tCc/tTc 0 +LRRC37B UCSF GRCh37 17 30376161 30376161 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 176 126 374 0 ENST00000341671.7:c.2424C>T p.Ser808= p.S808= ENST00000341671 NM_052888.2 808 tcC/tcT 0 +LRRC43 UCSF GRCh37 12 122684865 122684865 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 47 104 0 ENST00000339777.4:c.1479C>T p.Ile493= p.I493= ENST00000339777 NM_152759.4 493 atC/atT 0 +LRRC46 UCSF GRCh37 17 45913823 45913823 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 45 75 0 ENST00000269025.4:c.577C>T p.Pro193Ser p.P193S ENST00000269025 NM_033413.3 193 Cca/Tca 0 +LRRC46 UCSF GRCh37 17 45914311 45914311 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 82 169 0 ENST00000269025.4:c.791C>T p.Ala264Val p.A264V ENST00000269025 NM_033413.3 264 gCc/gTc 0 +LRRC47 UCSF GRCh37 1 3712429 3712429 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 14 12 0 ENST00000378251.1:c.612C>T p.Leu204= p.L204= ENST00000378251 NM_020710.2 204 ctC/ctT 0 +LRRC4B UCSF GRCh37 19 51022257 51022257 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 30 23 49 0 ENST00000389201.3:c.713G>A p.Gly238Asp p.G238D ENST00000389201 NM_001080457.1 238 gGc/gAc 0 +LRRC56 UCSF GRCh37 11 550220 550220 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 2 23 39 0 ENST00000270115.7:c.572C>T p.Thr191Ile p.T191I ENST00000270115 NM_198075.3 191 aCc/aTc 0 +LRRC56 UCSF GRCh37 11 551933 551933 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 2 23 51 0 ENST00000270115.7:c.1004C>T p.Thr335Ile p.T335I ENST00000270115 NM_198075.3 335 aCc/aTc 0 +LRRC61 UCSF GRCh37 7 150034028 150034028 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 45 98 0 ENST00000323078.7:c.78C>T p.Gly26= p.G26= ENST00000323078 NM_023942.2 26 ggC/ggT 0 +LRRC7 UCSF GRCh37 1 70257745 70257745 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 166 85 229 0 ENST00000035383.5:c.209C>T p.Ala70Val p.A70V ENST00000035383 NM_020794.2 70 gCt/gTt 0 +LRRFIP1 UCSF GRCh37 2 238628200 238628200 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 58 125 0 ENST00000392000.4:c.188G>A p.Arg63Lys p.R63K ENST00000392000 NM_001137552.1 63 aGa/aAa 0 +LRRK2 UCSF GRCh37 12 40728953 40728953 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 72 98 0 ENST00000298910.7:c.5942G>A p.Gly1981Asp p.G1981D ENST00000298910 NM_198578.3 1981 gGt/gAt 0 +LRRK2 UCSF GRCh37 12 40734120 40734120 + synonymous_variant Silent SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 43 143 243 0 ENST00000298910.7:c.5973A>C p.Ile1991= p.I1991= ENST00000298910 NM_198578.3 1991 atA/atC 0 +LRRN2 UCSF GRCh37 1 204588972 204588972 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 26 57 0 ENST00000367175.1:c.149C>T p.Ala50Val p.A50V ENST00000367175 50 gCt/gTt 0 +LRRTM2 UCSF GRCh37 5 138208784 138208784 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 217 186 317 0 ENST00000274711.6:c.1466C>T p.Pro489Leu p.P489L ENST00000274711 NM_015564.2 489 cCc/cTc 0 +LRTM2 UCSF GRCh37 12 1943854 1943854 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 24 63 0 ENST00000299194.1:c.1080C>T p.His360= p.H360= ENST00000299194 360 caC/caT 0 +LRWD1 UCSF GRCh37 7 102106690 102106690 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 60 118 0 ENST00000292616.5:c.405G>A p.Glu135= p.E135= ENST00000292616 NM_152892.1 135 gaG/gaA 0 +LSAMP UCSF GRCh37 3 115560705 115560705 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 76 158 0 ENST00000490035.2:c.906C>T p.Ser302= p.S302= ENST00000490035 NM_002338.3 302 agC/agT 0 +LSM14B UCSF GRCh37 20 60699695 60699695 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 131 102 254 0 ENST00000279068.6:c.150C>T p.Asp50= p.D50= ENST00000279068 NM_144703.2 50 gaC/gaT 0 +LTB4R2 UCSF GRCh37 14 24780661 24780661 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 30 82 0 ENST00000528054.1:c.884G>A p.Gly295Glu p.G295E ENST00000528054 295 gGa/gAa 0 +LTBP4 UCSF GRCh37 19 41128531 41128531 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 18 21 31 0 ENST00000308370.7:c.3641G>A p.Gly1214Asp p.G1214D ENST00000308370 NM_001042544.1 1214 gGc/gAc 0 +LTK UCSF GRCh37 15 41796765 41796765 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 71 159 0 ENST00000263800.6:c.2194G>A p.Val732Met p.V732M ENST00000263800 NM_002344.5 732 Gtg/Atg 0 +LTN1 UCSF GRCh37 21 30329198 30329198 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 52 133 0 ENST00000361371.5:c.2965C>T p.Gln989Ter p.Q989* ENST00000361371 989 Cag/Tag 0 +LTN1 UCSF GRCh37 21 30365211 30365211 + upstream_gene_variant 5'Flank SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 30 30 81 0 ENST00000361371 0 +LYZL2 UCSF GRCh37 10 30918612 30918612 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 190 35 165 0 ENST00000375318.2:c.23G>A p.Cys8Tyr p.C8Y ENST00000375318 NM_183058.2 8 tGc/tAc 0 +MAGEA10-MAGEA5 UCSF GRCh37 X 151283771 151283771 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 99 96 0 ENST00000427663.2:n.447G>A *149* ENST00000427663 0 +MAGEA8 UCSF GRCh37 X 149013490 149013490 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 113 113 0 ENST00000286482.1:c.444C>T p.Asn148= p.N148= ENST00000286482 NM_005364.4 148 aaC/aaT 0 +MAGEB1 UCSF GRCh37 X 30269223 30269223 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 3 38 56 0 ENST00000378981.3:c.613C>T p.Leu205= p.L205= ENST00000378981 NM_002363.4 205 Ctg/Ttg 0 +MAGEB16 UCSF GRCh37 X 35820630 35820630 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 66 68 0 ENST00000399985.1:c.317G>A p.Arg106Lys p.R106K ENST00000399985 106 aGg/aAg 0 +MAGI3 UCSF GRCh37 1 114189228 114189228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 126 106 162 0 ENST00000307546.9:c.2119G>A p.Val707Ile p.V707I ENST00000307546 NM_001142782.1 707 Gtc/Atc 0 +MAGI3 UCSF GRCh37 1 114196583 114196583 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 171 116 310 0 ENST00000307546.9:c.2572G>A p.Glu858Lys p.E858K ENST00000307546 NM_001142782.1 858 Gaa/Aaa 0 +MAGI3 UCSF GRCh37 1 114226361 114226361 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 106 199 0 ENST00000307546.9:c.4171G>A p.Gly1391Arg p.G1391R ENST00000307546 NM_001142782.1 1391 Gga/Aga 0 +MAL2 UCSF GRCh37 8 120252508 120252508 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 161 120 221 0 ENST00000276681.6:c.407C>T p.Thr136Ile p.T136I ENST00000276681 NM_052886.2 136 aCc/aTc 0 +MAMDC2 UCSF GRCh37 9 72840741 72840741 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 40 92 0 ENST00000377182.4:c.1987C>T p.Pro663Ser p.P663S ENST00000377182 NM_153267.4 663 Ccc/Tcc 0 +MANBA UCSF GRCh37 4 103571823 103571823 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 92 188 0 ENST00000226578.4:c.1740G>A p.Lys580= p.K580= ENST00000226578 NM_005908.3 580 aaG/aaA 0 +MANEA UCSF GRCh37 6 96034533 96034533 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 91 176 0 ENST00000358812.4:c.218C>T p.Thr73Ile p.T73I ENST00000358812 NM_024641.3 73 aCc/aTc 0 +MAP1B UCSF GRCh37 5 71491723 71491723 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 140 284 0 ENST00000296755.7:c.2541G>A p.Glu847= p.E847= ENST00000296755 NM_005909.3 847 gaG/gaA 0 +MAP2K4 UCSF GRCh37 17 12016621 12016621 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 108 84 203 0 ENST00000353533.5:c.757C>T p.Gln253Ter p.Q253* ENST00000353533 NM_003010.3 253 Cag/Tag 0 +MAP3K1 UCSF GRCh37 5 56174819 56174819 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 86 186 0 ENST00000399503.3:c.1978G>A p.Ala660Thr p.A660T ENST00000399503 NM_005921.1 660 Gcc/Acc 0 +MAP3K1 UCSF GRCh37 5 56177605 56177605 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 91 186 0 ENST00000399503.3:c.2578G>A p.Ala860Thr p.A860T ENST00000399503 NM_005921.1 860 Gca/Aca 0 +MAP3K15 UCSF GRCh37 X 19444406 19444406 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 103 92 0 ENST00000338883.4:c.1222G>A p.Val408Ile p.V408I ENST00000338883 NM_001001671.3 408 Gtt/Att 0 +MAP3K4 UCSF GRCh37 6 161469930 161469930 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 52 135 0 ENST00000392142.4:c.626C>T p.Pro209Leu p.P209L ENST00000392142 NM_005922.2 209 cCt/cTt 0 +MAPK10 UCSF GRCh37 4 87022299 87022299 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 73 130 0 ENST00000359221.3:c.636G>A p.Arg212= p.R212= ENST00000359221 212 agG/agA 0 +MAPKAPK3 UCSF GRCh37 3 50655216 50655216 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 30 67 0 ENST00000357955.2:c.219+1G>A p.X73_splice ENST00000357955 NM_001243925.1 0 +MAPKBP1 UCSF GRCh37 15 42116180 42116180 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 64 166 0 ENST00000456763.2:c.4152C>T p.Asn1384= p.N1384= ENST00000456763 NM_001128608.1 1384 aaC/aaT 0 +MARCH6 UCSF GRCh37 5 10394868 10394868 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 26 64 0 ENST00000274140.5:c.832C>T p.Leu278= p.L278= ENST00000274140 NM_005885.3 278 Cta/Tta 0 +MARS2 UCSF GRCh37 2 198570902 198570902 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 59 136 0 ENST00000282276.6:c.773G>A p.Arg258Lys p.R258K ENST00000282276 NM_138395.3 258 aGa/aAa 0 +MAST3 UCSF GRCh37 19 18256562 18256562 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 14 32 0 ENST00000262811.6:c.2962G>A p.Asp988Asn p.D988N ENST00000262811 NM_015016.1 988 Gac/Aac 0 +MASTL UCSF GRCh37 10 27448577 27448577 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 247 87 200 0 ENST00000375940.4:c.354C>T p.Val118= p.V118= ENST00000375940 118 gtC/gtT 0 +MATR3 UCSF GRCh37 5 138657666 138657666 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 75 190 0 ENST00000394805.3:c.1682G>A p.Gly561Glu p.G561E ENST00000394805 NM_001194955.1 561 gGg/gAg 0 +MAVS UCSF GRCh37 20 3845391 3845391 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0015 P18_Rec Untested WXS Illumina HiSeq 88 71 143 0 ENST00000428216.2:c.1114G>A p.Val372Met p.V372M ENST00000428216 NM_020746.4 372 Gtg/Atg 0 +MBD3 UCSF GRCh37 19 1585198 1585198 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 17 31 0 ENST00000434436.3:c.126G>A p.Lys42= p.K42= ENST00000434436 NM_001281453.1 42 aaG/aaA 0 +MBD6 UCSF GRCh37 12 57918856 57918856 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 44 112 0 ENST00000355673.3:c.337C>T p.Leu113= p.L113= ENST00000355673 NM_052897.3 113 Ctg/Ttg 0 +MBNL3 UCSF GRCh37 X 131540357 131540357 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 64 86 0 ENST00000370853.3:c.241G>A p.Glu81Lys p.E81K ENST00000370853 NM_018388.3 81 Gag/Aag 0 +MBOAT7 UCSF GRCh37 19 54677978 54677978 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 64 122 0 ENST00000245615.1:c.1179G>A p.Lys393= p.K393= ENST00000245615 NM_024298.3 393 aaG/aaA 0 +MCCC2 UCSF GRCh37 5 70948514 70948514 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 47 133 0 ENST00000340941.6:c.1507G>A p.Ala503Thr p.A503T ENST00000340941 NM_022132.4 503 Gcg/Acg 0 +MCHR2 UCSF GRCh37 6 100395771 100395771 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 96 251 0 ENST00000281806.2:c.259C>T p.Pro87Ser p.P87S ENST00000281806 NM_001040179.1 87 Cct/Tct 0 +MCM3 UCSF GRCh37 6 52141149 52141149 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 34 83 0 ENST00000229854.7:c.1291G>A p.Val431Met p.V431M ENST00000229854 431 Gtg/Atg 0 +MDH2 UCSF GRCh37 7 75686800 75686800 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 48 100 0 ENST00000315758.5:c.308C>T p.Pro103Leu p.P103L ENST00000315758 NM_005918.2 103 cCc/cTc 0 +MDN1 UCSF GRCh37 6 90402360 90402360 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 111 228 0 ENST00000369393.3:c.10389G>A p.Lys3463= p.K3463= ENST00000369393 3463 aaG/aaA 0 +MED11 UCSF GRCh37 17 4636437 4636437 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 53 87 0 ENST00000293777.5:c.309G>A p.Lys103= p.K103= ENST00000293777 NM_001001683.2 103 aaG/aaA 0 +MED13 UCSF GRCh37 17 60042453 60042453 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 57 132 0 ENST00000397786.2:c.4758G>A p.Gly1586= p.G1586= ENST00000397786 NM_005121.2 1586 ggG/ggA 0 +MED13L UCSF GRCh37 12 116429432 116429432 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 46 131 0 ENST00000281928.3:c.3327C>T p.Leu1109= p.L1109= ENST00000281928 NM_015335.4 1109 ctC/ctT 0 +MED27 UCSF GRCh37 9 134889740 134889740 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 68 110 0 ENST00000292035.5:c.463C>T p.Leu155Phe p.L155F ENST00000292035 NM_004269.3 155 Ctt/Ttt 0 +MED27 UCSF GRCh37 9 134889742 134889742 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 59 109 0 ENST00000292035.5:c.461C>T p.Thr154Ile p.T154I ENST00000292035 NM_004269.3 154 aCt/aTt 0 +MED28 UCSF GRCh37 4 17625266 17625266 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 62 144 0 ENST00000237380.7:c.382C>T p.Leu128= p.L128= ENST00000237380 NM_025205.3 128 Cta/Tta 0 +MED4 UCSF GRCh37 13 48669160 48669160 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 27 58 0 ENST00000258648.2:c.55G>A p.Gly19Arg p.G19R ENST00000258648 NM_014166.3 19 Gga/Aga 0 +MED4 UCSF GRCh37 13 48669152 48669152 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 30 45 0 ENST00000258648.2:c.63G>A p.Ala21= p.A21= ENST00000258648 NM_014166.3 21 gcG/gcA 0 +MEGF6 UCSF GRCh37 1 3407119 3407119 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 9 33 0 ENST00000356575.4:c.4599C>T p.Ser1533= p.S1533= ENST00000356575 NM_001409.3 1533 tcC/tcT 0 +MEGF8 UCSF GRCh37 19 42860343 42860343 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 7 27 0 ENST00000251268.6:c.4501G>A p.Ala1501Thr p.A1501T ENST00000251268 1501 Gcc/Acc 0 +MEOX2 UCSF GRCh37 7 15725839 15725839 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 11 32 0 ENST00000262041.5:c.189G>A p.Gln63= p.Q63= ENST00000262041 NM_005924.4 63 caG/caA 0 +MEP1A UCSF GRCh37 6 46797172 46797172 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 144 105 216 0 ENST00000230588.4:c.1008C>T p.Tyr336= p.Y336= ENST00000230588 NM_005588.2 336 taC/taT 0 +MEPCE UCSF GRCh37 7 100030654 100030654 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 83 176 0 ENST00000310512.2:c.1784G>A p.Gly595Asp p.G595D ENST00000310512 NM_019606.5 595 gGc/gAc 0 +METTL22 UCSF GRCh37 16 8722649 8722649 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 62 130 1 ENST00000381920.3:c.196G>A p.Gly66Ser p.G66S ENST00000381920 NM_024109.2 66 Ggt/Agt 0 +METTL3 UCSF GRCh37 14 21967728 21967728 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 99 207 0 ENST00000298717.4:c.1360G>A p.Glu454Lys p.E454K ENST00000298717 NM_019852.3 454 Gaa/Aaa 0 +MEX3C UCSF GRCh37 18 48703067 48703067 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 110 218 0 ENST00000406189.3:c.1634C>T p.Ser545Phe p.S545F ENST00000406189 NM_016626.4 545 tCt/tTt 0 +MFRP UCSF GRCh37 11 119215654 119215654 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 6 24 0 ENST00000449574.2:c.702C>T p.Val234= p.V234= ENST00000449574 234 gtC/gtT 0 +MGA UCSF GRCh37 15 42041421 42041421 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 227 176 332 0 ENST00000219905.7:c.5616G>A p.Gly1872= p.G1872= ENST00000219905 NM_001164273.1 1872 ggG/ggA 0 +MGMT UCSF GRCh37 10 131506280 131506280 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 87 173 0 ENST00000306010.7:c.340G>A p.Ala114Thr p.A114T ENST00000306010 NM_002412.3 114 Gct/Act 0 +MGRN1 UCSF GRCh37 16 4732837 4732837 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 15 51 0 ENST00000399577.5:c.1372C>T p.Pro458Ser p.P458S ENST00000399577 NM_001142290.2 458 Ccg/Tcg 0 +MGRN1 UCSF GRCh37 16 4730053 4730053 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 45 103 0 ENST00000399577.5:c.1086G>A p.Lys362= p.K362= ENST00000399577 NM_001142290.2 362 aaG/aaA 0 +MGST1 UCSF GRCh37 12 16510545 16510545 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 41 106 0 ENST00000010404.2:c.133G>A p.Ala45Thr p.A45T ENST00000010404 NM_145792.2 45 Gcc/Acc 0 +MIA3 UCSF GRCh37 1 222826618 222826618 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 72 164 0 ENST00000344922.5:c.4258G>A p.Glu1420Lys p.E1420K ENST00000344922 NM_198551.2 1420 Gaa/Aaa 0 +MIA3 UCSF GRCh37 1 222802863 222802863 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 69 168 0 ENST00000344922.5:c.2301G>A p.Gly767= p.G767= ENST00000344922 NM_198551.2 767 ggG/ggA 0 +MID2 UCSF GRCh37 X 107084129 107084129 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 111 120 0 ENST00000262843.6:c.234C>T p.Thr78= p.T78= ENST00000262843 NM_052817.2 78 acC/acT 0 +MIER1 UCSF GRCh37 1 67396083 67396083 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 17 39 0 ENST00000355356.3:c.9G>A p.Glu3= p.E3= ENST00000355356 NM_001077701.2 3 gaG/gaA 0 +MIER2 UCSF GRCh37 19 327170 327170 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 103 187 0 ENST00000264819.4:c.456C>T p.Ser152= p.S152= ENST00000264819 NM_017550.1 152 tcC/tcT 0 +MKI67 UCSF GRCh37 10 129911709 129911709 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 150 89 219 0 ENST00000368654.3:c.1638C>T p.Val546= p.V546= ENST00000368654 NM_002417.4 546 gtC/gtT 0 +MKL2 UCSF GRCh37 16 14340383 14340383 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 154 73 141 0 ENST00000318282.5:c.1266C>T p.Thr422= p.T422= ENST00000318282 422 acC/acT 0 +MLL UCSF GRCh37 11 118360597 118360597 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 85 141 0 ENST00000389506.5:c.4570G>A p.Val1524Ile p.V1524I ENST00000389506 1524 Gtc/Atc 0 +MLL2 UCSF GRCh37 12 49431402 49431402 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 9 32 60 0 ENST00000301067.7:c.9737C>T p.Pro3246Leu p.P3246L ENST00000301067 NM_003482.3 3246 cCc/cTc 0 +MLL2 UCSF GRCh37 12 49431257 49431257 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 25 78 0 ENST00000301067.7:c.9882C>T p.Ala3294= p.A3294= ENST00000301067 NM_003482.3 3294 gcC/gcT 0 +MLL3 UCSF GRCh37 7 151875061 151875061 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 45 119 0 ENST00000262189.6:c.7477C>T p.Pro2493Ser p.P2493S ENST00000262189 NM_170606.2 2493 Ccg/Tcg 0 +MLL4 UCSF GRCh37 19 36218834 36218834 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 17 21 0 ENST00000420124.1:c.4445G>A p.Gly1482Glu p.G1482E ENST00000420124 1482 gGa/gAa 0 +MLL4 UCSF GRCh37 19 36220182 36220182 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 25 50 0 ENST00000420124.1:c.4902C>T p.Ala1634= p.A1634= ENST00000420124 1634 gcC/gcT 0 +MLL4 UCSF GRCh37 19 36221731 36221731 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 20 76 0 ENST00000420124.1:c.5400G>A p.Glu1800= p.E1800= ENST00000420124 1800 gaG/gaA 0 +MLLT10 UCSF GRCh37 10 21827796 21827796 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.300,1000g2011may_all_0.31727,snp132_rs1802669 P18_Rec Untested WXS Illumina HiSeq 194 83 148 0 ENST00000307729.7:c.195G>A p.Pro65= p.P65= ENST00000307729 65 ccG/ccA 0 +MLPH UCSF GRCh37 2 238419422 238419422 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 18 74 0 ENST00000264605.3:c.316C>T p.Pro106Ser p.P106S ENST00000264605 NM_024101.6 106 Ccc/Tcc 0 +MMAA UCSF GRCh37 4 146567273 146567273 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 156 110 248 0 ENST00000281317.5:c.698G>A p.Gly233Glu p.G233E ENST00000281317 NM_172250.2 233 gGa/gAa 0 +MMACHC UCSF GRCh37 1 45974779 45974779 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 124 222 0 ENST00000401061.4:c.741C>T p.Ser247= p.S247= ENST00000401061 NM_015506.2 247 tcC/tcT 0 +MME UCSF GRCh37 3 154884718 154884718 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 121 200 0 ENST00000360490.2:c.1688C>T p.Pro563Leu p.P563L ENST00000360490 NM_007289.2 563 cCc/cTc 0 +MMP24 UCSF GRCh37 20 33842359 33842359 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 227 191 363 0 ENST00000246186.6:c.619C>T p.Pro207Ser p.P207S ENST00000246186 NM_006690.3 207 Cca/Tca 0 +MMP7 UCSF GRCh37 11 102398543 102398543 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 97 237 0 ENST00000260227.4:c.280G>A p.Glu94Lys p.E94K ENST00000260227 NM_002423.3 94 Gaa/Aaa 0 +MMP8 UCSF GRCh37 11 102584500 102584500 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 170 101 250 0 ENST00000236826.3:c.1279G>A p.Val427Ile p.V427I ENST00000236826 NM_002424.2 427 Gtt/Att 0 +MOGAT3 UCSF GRCh37 7 100841566 100841566 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 33 57 0 ENST00000223114.4:c.574G>A p.Gly192Arg p.G192R ENST00000223114 NM_178176.2 192 Ggg/Agg 0 +MORN4 UCSF GRCh37 10 99379358 99379358 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 111 232 0 ENST00000307450.6:c.53G>A p.Gly18Asp p.G18D ENST00000307450 NM_178832.3 18 gGc/gAc 0 +MORN5 UCSF GRCh37 9 124922265 124922265 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 49 152 0 ENST00000373764.3:c.14G>A p.Gly5Glu p.G5E ENST00000373764 NM_198469.2 5 gGg/gAg 0 +MOSC1 UCSF GRCh37 1 220971342 220971342 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.00182 P18_Rec somatic WXS Sanger Illumina HiSeq 196 167 298 0 ENST00000366910.5:c.739G>A p.Asp247Asn p.D247N ENST00000366910 NM_022746.3 247 Gat/Aat 0 +MPDZ UCSF GRCh37 9 13110053 13110053 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 119 210 0 ENST00000319217.7:c.5840G>A p.Gly1947Glu p.G1947E ENST00000319217 NM_001261406.1 1947 gGa/gAa 0 +MPO UCSF GRCh37 17 56350997 56350997 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 77 162 0 ENST00000225275.3:c.1399C>T p.Leu467= p.L467= ENST00000225275 NM_000250.1 467 Ctg/Ttg 0 +MRFAP1 UCSF GRCh37 4 6642626 6642626 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 102 166 0 ENST00000320912.4:c.37G>A p.Glu13Lys p.E13K ENST00000320912 NM_001272053.1 13 Gag/Aag 0 +MRPL14 UCSF GRCh37 6 44084277 44084277 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 155 112 234 0 ENST00000372014.3:c.71+1G>A p.X24_splice ENST00000372014 NM_032111.2 0 +MRPL34 UCSF GRCh37 19 17417154 17417154 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 25 0 ENST00000252602.1:c.245G>A p.Arg82Gln p.R82Q ENST00000252602 NM_023937.3 82 cGa/cAa 0 +MRPL36 UCSF GRCh37 5 1798955 1798955 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 39 123 0 ENST00000382647.7:c.95G>A p.Gly32Glu p.G32E ENST00000382647 32 gGa/gAa 0 +MRPL52 UCSF GRCh37 14 23299290 23299290 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 35 76 0 ENST00000355151.5:c.60C>T p.Ala20= p.A20= ENST00000355151 NM_181306.2 20 gcC/gcT 0 +MRPL9 UCSF GRCh37 1 151732528 151732528 + stop_lost Nonstop_Mutation SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 52 104 0 ENST00000368830.3:c.802T>A p.Ter268LysextTer23 p.*268Kext*23 ENST00000368830 NM_031420.2 268 Taa/Aaa 0 +MRPS16 UCSF GRCh37 10 75011752 75011752 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 34 59 0 ENST00000372945.3:c.43G>A p.Gly15Ser p.G15S ENST00000372945 NM_016065.3 15 Ggc/Agc 0 +MRPS18B UCSF GRCh37 6 30593558 30593558 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 66 132 0 ENST00000259873.4:c.761C>T p.Pro254Leu p.P254L ENST00000259873 NM_014046.3 254 cCt/cTt 0 +MRPS18B UCSF GRCh37 6 30587270 30587270 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 68 120 0 ENST00000259873.4:c.79G>A p.Val27Ile p.V27I ENST00000259873 NM_014046.3 27 Gtt/Att 0 +MRPS5 UCSF GRCh37 2 95773982 95773982 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 78 158 0 ENST00000272418.2:c.575G>A p.Gly192Glu p.G192E ENST00000272418 NM_031902.3 192 gGa/gAa 0 +MS4A6E UCSF GRCh37 11 60105419 60105419 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 47 137 0 ENST00000300182.4:c.353C>T p.Ala118Val p.A118V ENST00000300182 NM_139249.2 118 gCt/gTt 0 +MSH2 UCSF GRCh37 2 47709944 47709944 + synonymous_variant Silent SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 16 56 125 0 ENST00000233146.2:c.2661C>T p.Phe887= p.F887= ENST00000233146 NM_000251.2 887 ttC/ttT 0 +MSH3 UCSF GRCh37 5 79974745 79974745 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 159 94 193 0 ENST00000265081.6:c.1174-1G>A p.X392_splice ENST00000265081 NM_002439.4 0 +MSH5 UCSF GRCh37 6 31713013 31713013 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 72 53 118 0 ENST00000375750.3:c.684-1G>A p.X228_splice ENST00000375750 NM_172165.3 0 +MSLNL UCSF GRCh37 16 830474 830474 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 203 75 196 0 ENST00000442466.1:c.38-312C>T *13* ENST00000442466 0 +MST4 UCSF GRCh37 X 131206346 131206346 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 44 63 0 ENST00000394334.2:c.983C>T p.Thr328Ile p.T328I ENST00000394334 NM_016542.3 328 aCc/aTc 0 +MTA1 UCSF GRCh37 14 105927194 105927194 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 31 60 0 ENST00000331320.7:c.846G>A p.Arg282= p.R282= ENST00000331320 NM_004689.3 282 agG/agA 0 +MTA2 UCSF GRCh37 11 62361989 62361989 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 84 183 0 ENST00000278823.2:c.1691C>T p.Thr564Ile p.T564I ENST00000278823 NM_004739.3 564 aCt/aTt 0 +MTF1 UCSF GRCh37 1 38280883 38280883 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 65 138 0 ENST00000373036.4:c.2187G>A p.Pro729= p.P729= ENST00000373036 NM_005955.2 729 ccG/ccA 0 +MTL5 UCSF GRCh37 11 68518092 68518092 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 5 22 0 ENST00000255087.5:c.37C>T p.Pro13Ser p.P13S ENST00000255087 NM_004923.3 13 Ccc/Tcc 0 +MTMR3 UCSF GRCh37 22 30394841 30394841 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 0 25 44 0 ENST00000401950.2:c.552G>A p.Lys184= p.K184= ENST00000401950 NM_021090.3 184 aaG/aaA 0 +MTR UCSF GRCh37 1 237001873 237001873 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 75 153 0 ENST00000366577.5:c.1489G>A p.Val497Ile p.V497I ENST00000366577 NM_000254.2 497 Gtc/Atc 0 +MTSS1L UCSF GRCh37 16 70698214 70698214 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 13 16 0 ENST00000338779.6:c.1610C>T p.Ala537Val p.A537V ENST00000338779 NM_138383.2 537 gCc/gTc 0 +MTSS1L UCSF GRCh37 16 70698015 70698015 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 8 19 0 ENST00000338779.6:c.1809C>T p.Gly603= p.G603= ENST00000338779 NM_138383.2 603 ggC/ggT 0 +MTUS1 UCSF GRCh37 8 17612340 17612340 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 193 121 283 0 ENST00000262102.6:c.977G>A p.Ser326Asn p.S326N ENST00000262102 NM_001001924.2 326 aGc/aAc 0 +MTUS1 UCSF GRCh37 8 17612346 17612346 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 117 273 0 ENST00000262102.6:c.971C>T p.Ser324Leu p.S324L ENST00000262102 NM_001001924.2 324 tCa/tTa 0 +MTX2 UCSF GRCh37 2 177193039 177193039 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 146 110 193 0 ENST00000249442.6:c.304G>A p.Gly102Arg p.G102R ENST00000249442 NM_006554.4 102 Ggg/Agg 0 +MUC12 UCSF GRCh37 7 100644479 100644479 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 351 160 480 0 ENST00000379442.3:c.11064G>A p.Gln3688= p.Q3688= ENST00000379442 3688 caG/caA 0 +MUC13 UCSF GRCh37 3 124646780 124646780 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 127 95 189 0 ENST00000311075.3:c.110G>A p.Gly37Asp p.G37D ENST00000311075 NM_033049.3 37 gGt/gAt 0 +MUC13 UCSF GRCh37 3 124646678 124646678 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 203 155 301 0 ENST00000311075.3:c.212C>T p.Pro71Leu p.P71L ENST00000311075 NM_033049.3 71 cCc/cTc 0 +MUC16 UCSF GRCh37 19 8993478 8993478 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 143 106 219 0 ENST00000397910.4:c.41611C>T p.Pro13871Ser p.P13871S ENST00000397910 NM_024690.2 13871 Cct/Tct 0 +MUC16 UCSF GRCh37 19 9049298 9049298 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 244 185 382 0 ENST00000397910.4:c.32333C>T p.Ser10778Leu p.S10778L ENST00000397910 NM_024690.2 10778 tCg/tTg 0 +MUC16 UCSF GRCh37 19 9061560 9061560 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.024,1000g2011may_all_0.0668,snp132_rs56807558 P18_Rec Untested WXS Illumina HiSeq 212 49 324 0 ENST00000397910.4:c.25886C>T p.Thr8629Met p.T8629M ENST00000397910 NM_024690.2 8629 aCg/aTg 0 +MUC16 UCSF GRCh37 19 9066635 9066635 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 247 194 388 0 ENST00000397910.4:c.20811G>A p.Glu6937= p.E6937= ENST00000397910 NM_024690.2 6937 gaG/gaA 0 +MUC16 UCSF GRCh37 19 9061022 9061022 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 223 145 306 0 ENST00000397910.4:c.26424C>T p.Ser8808= p.S8808= ENST00000397910 NM_024690.2 8808 agC/agT 0 +MUC16 UCSF GRCh37 19 9066128 9066128 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 166 127 290 0 ENST00000397910.4:c.21318C>T p.Thr7106= p.T7106= ENST00000397910 NM_024690.2 7106 acC/acT 0 +MUC17 UCSF GRCh37 7 100696713 100696713 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 24 80 0 ENST00000306151.4:c.13359C>T p.Cys4453= p.C4453= ENST00000306151 NM_001040105.1 4453 tgC/tgT 0 +MUC17 UCSF GRCh37 7 100678195 100678195 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 257 176 371 0 ENST00000306151.4:c.3498T>C p.Pro1166= p.P1166= ENST00000306151 NM_001040105.1 1166 ccT/ccC 0 +MUC4 UCSF GRCh37 3 195513137 195513137 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 694 100 828 0 ENST00000463781.3:c.5314G>A p.Ala1772Thr p.A1772T ENST00000463781 NM_018406.6 1772 Gct/Act 0 +MUC4 UCSF GRCh37 3 195513194 195513194 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 451 167 617 0 ENST00000463781.3:c.5257G>A p.Ala1753Thr p.A1753T ENST00000463781 NM_018406.6 1753 Gca/Aca 0 +MVP UCSF GRCh37 16 29856151 29856151 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 77 149 0 ENST00000357402.5:c.1972G>A p.Val658Ile p.V658I ENST00000357402 NM_017458.3 658 Gtc/Atc 0 +MVP UCSF GRCh37 16 29842379 29842379 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 19 43 0 ENST00000357402.5:c.306G>A p.Gly102= p.G102= ENST00000357402 NM_017458.3 102 ggG/ggA 0 +MYBBP1A UCSF GRCh37 17 4455460 4455460 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 53 104 0 ENST00000254718.4:c.865G>A p.Val289Met p.V289M ENST00000254718 289 Gtg/Atg 0 +MYBPC1 UCSF GRCh37 12 102036311 102036311 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 30 54 0 ENST00000550270.1:c.705C>T p.Arg235= p.R235= ENST00000550270 235 cgC/cgT 0 +MYBPC2 UCSF GRCh37 19 50944141 50944141 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 26 55 0 ENST00000357701.5:c.577G>A p.Val193Met p.V193M ENST00000357701 NM_004533.3 193 Gtg/Atg 0 +MYCBP2 UCSF GRCh37 13 77635855 77635855 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 30 112 0 ENST00000357337.6:c.12731G>A p.Cys4244Tyr p.C4244Y ENST00000357337 4244 tGt/tAt 0 +MYCBP2 UCSF GRCh37 13 77669565 77669565 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 58 137 0 ENST00000357337.6:c.10013C>T p.Pro3338Leu p.P3338L ENST00000357337 3338 cCc/cTc 0 +MYCBP2 UCSF GRCh37 13 77763129 77763129 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 55 178 0 ENST00000357337.6:c.4094C>T p.Pro1365Leu p.P1365L ENST00000357337 1365 cCt/cTt 0 +MYH10 UCSF GRCh37 17 8381764 8381764 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 47 133 0 ENST00000269243.4:c.5505G>A p.Lys1835= p.K1835= ENST00000269243 NM_005964.3 1835 aaG/aaA 0 +MYH13 UCSF GRCh37 17 10231375 10231375 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 68 163 0 ENST00000252172.4:c.2499G>A p.Trp833Ter p.W833* ENST00000252172 NM_003802.2 833 tgG/tgA 0 +MYH13 UCSF GRCh37 17 10212743 10212743 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 18 21 34 0 ENST00000252172.4:c.4977G>A p.Leu1659= p.L1659= ENST00000252172 NM_003802.2 1659 ctG/ctA 0 +MYH15 UCSF GRCh37 3 108156540 108156540 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 142 106 246 0 ENST00000273353.3:c.3142G>A p.Gly1048Ser p.G1048S ENST00000273353 NM_014981.1 1048 Ggt/Agt 0 +MYH2 UCSF GRCh37 17 10447245 10447245 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 174 124 272 0 ENST00000245503.5:c.622G>A p.Glu208Lys p.E208K ENST00000245503 NM_017534.5 208 Gaa/Aaa 0 +MYH3 UCSF GRCh37 17 10533424 10533424 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 181 120 253 0 ENST00000583535.1:c.5547G>A p.Lys1849= p.K1849= ENST00000583535 NM_002470.3 1849 aaG/aaA 0 +MYH4 UCSF GRCh37 17 10353882 10353882 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 90 168 1 ENST00000255381.2:c.4069G>A p.Ala1357Thr p.A1357T ENST00000255381 NM_017533.2 1357 Gcc/Acc 0 +MYH4 UCSF GRCh37 17 10355605 10355605 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 90 205 0 ENST00000255381.2:c.3391G>A p.Ala1131Thr p.A1131T ENST00000255381 NM_017533.2 1131 Gcc/Acc 0 +MYH4 UCSF GRCh37 17 10348301 10348301 + stop_gained Nonsense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 113 226 0 ENST00000255381.2:c.5458G>T p.Glu1820Ter p.E1820* ENST00000255381 NM_017533.2 1820 Gag/Tag 0 +MYH6 UCSF GRCh37 14 23868031 23868031 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 77 162 0 ENST00000356287.3:c.1797G>A p.Lys599= p.K599= ENST00000356287 599 aaG/aaA 0 +MYH9 UCSF GRCh37 22 36684872 36684872 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 82 170 0 ENST00000216181.5:c.4671G>A p.Arg1557= p.R1557= ENST00000216181 NM_002473.4 1557 cgG/cgA 0 +MYL1 UCSF GRCh37 2 211163168 211163168 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 65 179 0 ENST00000352451.3:c.280G>T p.Val94Phe p.V94F ENST00000352451 NM_079420.2 94 Gtt/Ttt 0 +MYL12B UCSF GRCh37 18 3277370 3277370 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 123 194 0 ENST00000237500.5:c.304G>A p.Val102Ile p.V102I ENST00000237500 NM_033546.3 102 Gtc/Atc 0 +MYLK UCSF GRCh37 3 123383000 123383000 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 135 84 220 0 ENST00000360304.3:c.3937G>A p.Glu1313Lys p.E1313K ENST00000360304 NM_053025.3 1313 Gag/Aag 0 +MYO18A UCSF GRCh37 17 27417083 27417083 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 47 153 0 ENST00000527372.1:c.5422G>A p.Glu1808Lys p.E1808K ENST00000527372 NM_078471.3 1808 Gag/Aag 0 +MYO1F UCSF GRCh37 19 8616672 8616672 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 70 132 0 ENST00000338257.8:c.723C>T p.Thr241= p.T241= ENST00000338257 NM_012335.3 241 acC/acT 0 +MYO5C UCSF GRCh37 15 52548869 52548869 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 95 214 0 ENST00000261839.7:c.1362C>T p.Tyr454= p.Y454= ENST00000261839 NM_018728.3 454 taC/taT 0 +MYO9A UCSF GRCh37 15 72190819 72190819 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 129 252 0 ENST00000356056.5:c.4025G>A p.Ser1342Asn p.S1342N ENST00000356056 NM_006901.3 1342 aGc/aAc 0 +MYO9B UCSF GRCh37 19 17273863 17273863 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 55 103 0 ENST00000594824.1:c.1602G>A p.Gln534= p.Q534= ENST00000594824 534 caG/caA 0 +MYOC UCSF GRCh37 1 171605628 171605628 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 82 160 0 ENST00000037502.6:c.952C>T p.Leu318= p.L318= ENST00000037502 NM_000261.1 318 Ctg/Ttg 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 159 85 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +MYOF UCSF GRCh37 10 95069906 95069906 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 56 109 0 ENST00000359263.4:c.6018C>T p.Phe2006= p.F2006= ENST00000359263 NM_013451.3 2006 ttC/ttT 0 +MYOM1 UCSF GRCh37 18 3188831 3188831 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 62 151 0 ENST00000356443.4:c.686C>T p.Ala229Val p.A229V ENST00000356443 NM_019856.1 229 gCt/gTt 0 +MYOM1 UCSF GRCh37 18 3151867 3151867 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 165 97 251 0 ENST00000356443.4:c.1668G>A p.Trp556Ter p.W556* ENST00000356443 NM_019856.1 556 tgG/tgA 0 +MYOM1 UCSF GRCh37 18 3215153 3215153 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 37 107 0 ENST00000356443.4:c.69C>T p.Arg23= p.R23= ENST00000356443 NM_019856.1 23 cgC/cgT 0 +MYOZ3 UCSF GRCh37 5 150056363 150056363 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 86 63 177 0 ENST00000297130.4:c.682C>T p.Leu228Phe p.L228F ENST00000297130 NM_133371.4 228 Ctc/Ttc 0 +MYT1 UCSF GRCh37 20 62839012 62839012 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 74 151 0 ENST00000328439.1:c.463G>A p.Gly155Ser p.G155S ENST00000328439 NM_004535.2 155 Ggc/Agc 0 +MYT1L UCSF GRCh37 2 1796216 1796216 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 46 98 0 ENST00000399161.2:c.3297C>T p.Asn1099= p.N1099= ENST00000399161 NM_015025.2 1099 aaC/aaT 0 +MZF1 UCSF GRCh37 19 59074195 59074195 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 6 9 12 0 ENST00000215057.2:c.1449C>T p.Gly483= p.G483= ENST00000215057 NM_001267033.1 483 ggC/ggT 0 +N4BP2 UCSF GRCh37 4 40103856 40103856 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 157 119 289 0 ENST00000261435.6:c.391G>A p.Asp131Asn p.D131N ENST00000261435 NM_018177.4 131 Gat/Aat 0 +N4BP2 UCSF GRCh37 4 40119559 40119559 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 73 174 0 ENST00000261435.6:c.1735G>A p.Val579Met p.V579M ENST00000261435 NM_018177.4 579 Gtg/Atg 0 +NAA16 UCSF GRCh37 13 41894911 41894911 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 42 150 0 ENST00000379406.3:c.353G>A p.Arg118Lys p.R118K ENST00000379406 NM_024561.4 118 aGg/aAg 0 +NAA35 UCSF GRCh37 9 88593224 88593224 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 130 300 0 ENST00000361671.5:c.805G>A p.Ala269Thr p.A269T ENST00000361671 NM_024635.3 269 Gca/Aca 0 +NACAD UCSF GRCh37 7 45124894 45124894 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 6 13 0 ENST00000490531.2:c.885C>T p.Phe295= p.F295= ENST00000490531 NM_001146334.1 295 ttC/ttT 0 +NADSYN1 UCSF GRCh37 11 71183505 71183505 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 50 108 0 ENST00000319023.2:c.418G>A p.Glu140Lys p.E140K ENST00000319023 NM_018161.4 140 Gag/Aag 0 +NAPSA UCSF GRCh37 19 50861859 50861859 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 24 35 0 ENST00000253719.2:c.1214G>A p.Gly405Glu p.G405E ENST00000253719 NM_004851.1 405 gGa/gAa 0 +NASP UCSF GRCh37 1 46073426 46073426 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 40 111 0 ENST00000350030.3:c.843G>A p.Gln281= p.Q281= ENST00000350030 NM_002482.3 281 caG/caA 0 +NAT10 UCSF GRCh37 11 34153694 34153694 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 229 164 358 0 ENST00000257829.3:c.1543C>T p.Leu515Phe p.L515F ENST00000257829 NM_024662.2 515 Ctc/Ttc 0 +NAT8B UCSF GRCh37 2 73928149 73928149 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 138 257 0 ENST00000377712.2:n.284C>T *95* ENST00000377712 0 +NBEA UCSF GRCh37 13 35692373 35692373 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 27 84 0 ENST00000400445.3:c.2091G>A p.Gly697= p.G697= ENST00000400445 NM_015678.4 697 ggG/ggA 0 +NBPF14 UCSF GRCh37 1 148015760 148015760 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 256 156 423 0 ENST00000310701.10:c.888G>A p.Val297Ile p.V297I ENST00000310701 297 Gtc/Atc 0 +NBPF7 UCSF GRCh37 1 120382012 120382012 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 156 150 243 0 ENST00000401014.1:n.1254G>A *418* ENST00000401014 0 +NBPF9 UCSF GRCh37 1 144825474 144825474 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 290 146 467 0 ENST00000375552.4:c.1422G>A p.Ala475Thr p.A475T ENST00000375552 NM_001277444.1 475 Gct/Act 0 +NCAPH2 UCSF GRCh37 22 50956631 50956631 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 40 67 0 ENST00000420993.2:c.570G>A p.Gly190= p.G190= ENST00000420993 NM_001185011.1 190 ggG/ggA 0 +NCKAP1L UCSF GRCh37 12 54905614 54905614 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 73 170 0 ENST00000293373.6:c.763G>A p.Val255Ile p.V255I ENST00000293373 NM_005337.4 255 Gta/Ata 0 +NCKAP5 UCSF GRCh37 2 133540839 133540839 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 153 108 264 0 ENST00000409261.1:c.3545C>T p.Ser1182Phe p.S1182F ENST00000409261 NM_207363.2 1182 tCc/tTc 0 +NCKIPSD UCSF GRCh37 3 48717086 48717086 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 62 147 0 ENST00000294129.2:c.1411G>A p.Asp471Asn p.D471N ENST00000294129 NM_016453.3 471 Gat/Aat 0 +NCOA1 UCSF GRCh37 2 24949505 24949505 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 80 155 0 ENST00000348332.3:c.2647C>T p.Pro883Ser p.P883S ENST00000348332 NM_147233.2 883 Cca/Tca 0 +NCOA2 UCSF GRCh37 8 71069245 71069245 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 110 94 190 0 ENST00000452400.2:c.1355G>A p.Gly452Asp p.G452D ENST00000452400 NM_006540.2 452 gGc/gAc 0 +NCOA3 UCSF GRCh37 20 46264805 46264805 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.018,1000g2011may_all_0.0462,snp132_rs2230781 P18_Rec Untested WXS Illumina HiSeq 107 96 208 0 ENST00000371998.3:c.1675C>T p.Pro559Ser p.P559S ENST00000371998 559 Cca/Tca 0 +NCOR2 UCSF GRCh37 12 124971028 124971028 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 13 29 0 ENST00000405201.1:c.192G>A p.Arg64= p.R64= ENST00000405201 64 cgG/cgA 0 +NCR1 UCSF GRCh37 19 55420876 55420876 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 50 106 0 ENST00000291890.4:c.628G>A p.Val210Ile p.V210I ENST00000291890 NM_004829.6 210 Gtc/Atc 0 +NDC80 UCSF GRCh37 18 2574999 2574999 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 52 113 0 ENST00000261597.4:c.113C>T p.Pro38Leu p.P38L ENST00000261597 NM_006101.2 38 cCa/cTa 0 +NDST1 UCSF GRCh37 5 149901129 149901129 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 72 156 0 ENST00000261797.6:c.313G>A p.Glu105Lys p.E105K ENST00000261797 NM_001543.4 105 Gag/Aag 0 +NDST4 UCSF GRCh37 4 115769441 115769441 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 83 196 0 ENST00000264363.2:c.1870C>T p.Leu624Phe p.L624F ENST00000264363 NM_022569.1 624 Ctc/Ttc 0 +NDUFS1 UCSF GRCh37 2 207011800 207011800 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 73 178 0 ENST00000233190.6:c.564G>A p.Glu188= p.E188= ENST00000233190 NM_005006.6 188 gaG/gaA 0 +NDUFS8 UCSF GRCh37 11 67803812 67803812 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 35 48 0 ENST00000313468.5:c.465C>T p.Phe155= p.F155= ENST00000313468 NM_002496.3 155 ttC/ttT 0 +NEB UCSF GRCh37 2 152424671 152424671 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 75 178 0 ENST00000172853.10:c.12655G>A p.Glu4219Lys p.E4219K ENST00000172853 4219 Gag/Aag 0 +NEB UCSF GRCh37 2 152477474 152477474 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 108 185 0 ENST00000172853.10:c.9790C>T p.Pro3264Ser p.P3264S ENST00000172853 3264 Ccc/Tcc 0 +NEB UCSF GRCh37 2 152424833 152424833 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 89 174 0 ENST00000172853.10:c.12630C>T p.Asp4210= p.D4210= ENST00000172853 4210 gaC/gaT 0 +NEB UCSF GRCh37 2 152468757 152468757 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 104 258 0 ENST00000172853.10:c.11019C>T p.Cys3673= p.C3673= ENST00000172853 3673 tgC/tgT 0 +NEBL UCSF GRCh37 10 21134283 21134283 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 43 97 0 ENST00000377122.4:c.1131G>A p.Glu377= p.E377= ENST00000377122 NM_006393.2 377 gaG/gaA 0 +NECAB2 UCSF GRCh37 16 84005771 84005771 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 41 88 0 ENST00000305202.4:c.217G>A p.Asp73Asn p.D73N ENST00000305202 NM_019065.2 73 Gac/Aac 0 +NEO1 UCSF GRCh37 15 73528829 73528829 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 98 220 0 ENST00000261908.6:c.1433C>T p.Thr478Ile p.T478I ENST00000261908 NM_002499.3 478 aCc/aTc 0 +NETO1 UCSF GRCh37 18 70450940 70450940 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 105 189 0 ENST00000327305.6:c.841C>T p.Gln281Ter p.Q281* ENST00000327305 NM_138966.3 281 Cag/Tag 0 +NEURL4 UCSF GRCh37 17 7220873 7220873 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 52 111 0 ENST00000399464.2:c.4225G>A p.Ala1409Thr p.A1409T ENST00000399464 NM_032442.2 1409 Gct/Act 0 +NF1 UCSF GRCh37 17 29587442 29587442 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 182 98 247 0 ENST00000358273.4:c.4486C>T p.Leu1496Phe p.L1496F ENST00000358273 NM_001042492.2 1496 Ctt/Ttt 0 +NF1 UCSF GRCh37 17 29661958 29661958 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 124 73 159 0 ENST00000358273.4:c.5915C>T p.Thr1972Ile p.T1972I ENST00000358273 NM_001042492.2 1972 aCt/aTt 0 +NFATC2IP UCSF GRCh37 16 28965910 28965910 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 271 105 241 0 ENST00000320805.4:c.485G>A p.Gly162Asp p.G162D ENST00000320805 NM_032815.3 162 gGt/gAt 0 +NFIX UCSF GRCh37 19 13192670 13192670 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 35 74 0 ENST00000592199.1:c.1254+1G>A p.X418_splice ENST00000592199 0 +NFIX UCSF GRCh37 19 13136017 13136017 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 67 162 0 ENST00000592199.1:c.210G>A p.Lys70= p.K70= ENST00000592199 70 aaG/aaA 0 +NGEF UCSF GRCh37 2 233748155 233748155 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 10 36 0 ENST00000264051.3:c.1623C>T p.Asp541= p.D541= ENST00000264051 NM_019850.2 541 gaC/gaT 0 +NGEF UCSF GRCh37 2 233839466 233839466 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 153 137 246 0 ENST00000264051.3:c.135C>T p.Asp45= p.D45= ENST00000264051 NM_019850.2 45 gaC/gaT 0 +NHSL1 UCSF GRCh37 6 138752305 138752305 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 38 93 0 ENST00000427025.2:c.3189G>A p.Glu1063= p.E1063= ENST00000427025 NM_020464.1 1063 gaG/gaA 0 +NID2 UCSF GRCh37 14 52527059 52527059 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 32 53 0 ENST00000216286.5:c.550G>A p.Ala184Thr p.A184T ENST00000216286 NM_007361.3 184 Gca/Aca 0 +NIPSNAP1 UCSF GRCh37 22 29966495 29966495 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 23 63 0 ENST00000216121.7:c.125G>A p.Ser42Asn p.S42N ENST00000216121 NM_001202502.1 42 aGc/aAc 0 +NISCH UCSF GRCh37 3 52514312 52514312 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 40 83 0 ENST00000345716.4:c.1528+1G>A p.X510_splice ENST00000345716 NM_007184.3 0 +NLRC5 UCSF GRCh37 16 57111876 57111876 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 16 44 0 ENST00000262510.6:c.5025G>A p.Gly1675= p.G1675= ENST00000262510 NM_032206.4 1675 ggG/ggA 0 +NMUR1 UCSF GRCh37 2 232390053 232390053 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 31 74 0 ENST00000305141.4:c.982G>A p.Asp328Asn p.D328N ENST00000305141 NM_006056.4 328 Gat/Aat 0 +NNT UCSF GRCh37 5 43653298 43653298 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 40 71 0 ENST00000264663.5:c.2042C>T p.Ala681Val p.A681V ENST00000264663 NM_012343.3 681 gCt/gTt 0 +NOD2 UCSF GRCh37 16 50733518 50733518 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 59 136 0 ENST00000300589.2:c.193G>A p.Val65Ile p.V65I ENST00000300589 NM_022162.1 65 Gtc/Atc 0 +NOL11 UCSF GRCh37 17 65720295 65720295 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 70 126 0 ENST00000253247.4:c.650C>T p.Ser217Phe p.S217F ENST00000253247 NM_015462.3 217 tCt/tTt 0 +NOL11 UCSF GRCh37 17 65733707 65733707 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 119 267 0 ENST00000253247.4:c.1302G>A p.Gly434= p.G434= ENST00000253247 NM_015462.3 434 ggG/ggA 0 +NOL11 UCSF GRCh37 17 65734319 65734319 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 77 156 0 ENST00000253247.4:c.1611G>A p.Glu537= p.E537= ENST00000253247 NM_015462.3 537 gaG/gaA 0 +NOL8 UCSF GRCh37 9 95060548 95060548 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 39 85 0 ENST00000442668.2:c.3444C>T p.Asn1148= p.N1148= ENST00000442668 NM_017948.5 1148 aaC/aaT 0 +NOP16 UCSF GRCh37 5 175812280 175812280 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 59 164 0 ENST00000510123.1:c.335C>T p.Ser112Phe p.S112F ENST00000510123 NM_001256539.1 112 tCt/tTt 0 +NOTCH4 UCSF GRCh37 6 32168681 32168681 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 12 45 0 ENST00000375023.3:c.4242G>A p.Ala1414= p.A1414= ENST00000375023 NM_004557.3 1414 gcG/gcA 0 +NOX4 UCSF GRCh37 11 89069061 89069061 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 76 147 0 ENST00000263317.4:c.1568G>A p.Arg523His p.R523H ENST00000263317 523 cGt/cAt 0 +NPEPL1 UCSF GRCh37 20 57276164 57276164 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 28 34 0 ENST00000356091.6:c.772G>A p.Val258Met p.V258M ENST00000356091 NM_024663.3 258 Gtg/Atg 0 +NPEPPS UCSF GRCh37 17 45673785 45673785 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 49 134 0 ENST00000322157.4:c.1493C>T p.Thr498Ile p.T498I ENST00000322157 NM_006310.3 498 aCc/aTc 0 +NPFFR2 UCSF GRCh37 4 72897682 72897682 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 42 87 0 ENST00000308744.6:c.64G>A p.Ala22Thr p.A22T ENST00000308744 NM_004885.2 22 Gca/Aca 0 +NPHP3 UCSF GRCh37 3 132435724 132435724 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 79 159 0 ENST00000337331.5:c.700G>A p.Gly234Ser p.G234S ENST00000337331 NM_153240.4 234 Ggc/Agc 0 +NPR1 UCSF GRCh37 1 153660173 153660173 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 80 184 0 ENST00000368680.3:c.2156C>T p.Ala719Val p.A719V ENST00000368680 NM_000906.3 719 gCt/gTt 0 +NR2F1 UCSF GRCh37 5 92923623 92923623 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 50 128 0 ENST00000327111.3:c.464C>T p.Ala155Val p.A155V ENST00000327111 NM_005654.4 155 gCg/gTg 0 +NR3C1 UCSF GRCh37 5 142779230 142779230 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 80 192 0 ENST00000343796.2:c.1175G>A p.Gly392Asp p.G392D ENST00000343796 NM_001018075.1 392 gGc/gAc 0 +NR4A1 UCSF GRCh37 12 52449925 52449925 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 9 34 88 0 ENST00000243050.1:c.988G>A p.Val330Met p.V330M ENST00000243050 NM_002135.4 330 Gtg/Atg 0 +NR6A1 UCSF GRCh37 9 127302330 127302330 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 154 105 232 0 ENST00000487099.2:c.578G>A p.Gly193Asp p.G193D ENST00000487099 NM_001489.4 193 gGc/gAc 0 +NRF1 UCSF GRCh37 7 129330360 129330360 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 50 128 0 ENST00000223190.4:c.580C>T p.Pro194Ser p.P194S ENST00000223190 194 Cca/Tca 0 +NRM UCSF GRCh37 6 30656569 30656569 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 40 92 0 ENST00000259953.4:c.658C>T p.Leu220Phe p.L220F ENST00000259953 NM_007243.2 220 Ctt/Ttt 0 +NRP2 UCSF GRCh37 2 206608113 206608113 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 68 146 0 ENST00000360409.3:c.1478G>A p.Gly493Glu p.G493E ENST00000360409 NM_003872.2 493 gGa/gAa 0 +NRP2 UCSF GRCh37 2 206610533 206610533 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 10 82 0 ENST00000360409.3:c.1705C>A p.Gln569Lys p.Q569K ENST00000360409 NM_003872.2 569 Cag/Aag 0 +NRSN2 UCSF GRCh37 20 334046 334046 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 45 112 0 ENST00000382285.2:c.382G>A p.Val128Ile p.V128I ENST00000382285 128 Gtt/Att 0 +NSRP1 UCSF GRCh37 17 28512333 28512333 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 71 129 0 ENST00000247026.5:c.1318C>T p.Arg440Ter p.R440* ENST00000247026 NM_032141.3 440 Cga/Tga 0 +NSUN2 UCSF GRCh37 5 6616964 6616964 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 69 158 0 ENST00000264670.6:c.897G>A p.Gln299= p.Q299= ENST00000264670 NM_017755.5 299 caG/caA 0 +NSUN4 UCSF GRCh37 1 46827324 46827324 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 116 217 0 ENST00000474844.1:c.961G>A p.Val321Met p.V321M ENST00000474844 NM_199044.3 321 Gtg/Atg 0 +NT5DC1 UCSF GRCh37 6 116542237 116542237 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 61 136 0 ENST00000319550.4:c.550C>T p.Pro184Ser p.P184S ENST00000319550 NM_152729.2 184 Cca/Tca 0 +NTF4 UCSF GRCh37 19 49564937 49564937 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 17 50 0 ENST00000593537.1:c.318C>T p.Asp106= p.D106= ENST00000593537 106 gaC/gaT 0 +NTN4 UCSF GRCh37 12 96180889 96180889 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 58 161 0 ENST00000343702.4:c.413G>A p.Arg138Lys p.R138K ENST00000343702 NM_021229.3 138 aGg/aAg 0 +NTN5 UCSF GRCh37 19 49173998 49173998 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 19 44 0 ENST00000270235.4:c.246C>T p.Phe82= p.F82= ENST00000270235 NM_145807.1 82 ttC/ttT 0 +NTNG1 UCSF GRCh37 1 107867358 107867358 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 64 150 0 ENST00000370068.1:c.701G>A p.Gly234Glu p.G234E ENST00000370068 234 gGa/gAa 0 +NUDC UCSF GRCh37 1 27268067 27268067 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 22 41 0 ENST00000321265.5:c.279G>A p.Lys93= p.K93= ENST00000321265 NM_006600.3 93 aaG/aaA 0 +NUP155 UCSF GRCh37 5 37338020 37338020 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 57 160 0 ENST00000231498.3:c.1247G>A p.Gly416Asp p.G416D ENST00000231498 NM_153485.2 416 gGt/gAt 0 +NUP210 UCSF GRCh37 3 13384708 13384708 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 57 106 0 ENST00000254508.5:c.2931C>T p.Asp977= p.D977= ENST00000254508 NM_024923.3 977 gaC/gaT 0 +NUP210L UCSF GRCh37 1 153974448 153974448 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 57 116 0 ENST00000368559.3:c.4944C>T p.Cys1648= p.C1648= ENST00000368559 NM_207308.2 1648 tgC/tgT 0 +NUP214 UCSF GRCh37 9 134108860 134108860 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 45 102 0 ENST00000359428.5:c.6259G>A p.Gly2087Ser p.G2087S ENST00000359428 NM_005085.3 2087 Ggc/Agc 0 +NUP54 UCSF GRCh37 4 77065364 77065364 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 187 172 336 0 ENST00000264883.3:c.233G>A p.Gly78Asp p.G78D ENST00000264883 NM_001278603.1 78 gGt/gAt 0 +NXF3 UCSF GRCh37 X 102335083 102335083 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 134 153 0 ENST00000395065.3:c.989C>T p.Thr330Ile p.T330I ENST00000395065 NM_022052.1 330 aCc/aTc 0 +OAS2 UCSF GRCh37 12 113446917 113446917 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 141 129 250 0 ENST00000342315.4:c.1921C>T p.Pro641Ser p.P641S ENST00000342315 NM_016817.2 641 Ccc/Tcc 0 +OASL UCSF GRCh37 12 121469348 121469348 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 64 153 0 ENST00000257570.5:c.554G>A p.Gly185Glu p.G185E ENST00000257570 NM_003733.3 185 gGa/gAa 0 +OBSCN UCSF GRCh37 1 228559629 228559629 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 33 61 0 ENST00000422127.1:c.21150C>T p.His7050= p.H7050= ENST00000422127 NM_001098623.2 7050 caC/caT 0 +OCRL UCSF GRCh37 X 128723821 128723821 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 79 87 0 ENST00000371113.4:c.2470-1G>A p.X824_splice ENST00000371113 NM_000276.3 0 +ODF2 UCSF GRCh37 9 131262385 131262385 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 76 187 0 ENST00000434106.3:c.2341G>A p.Asp781Asn p.D781N ENST00000434106 NM_153433.1 781 Gat/Aat 0 +ODF3L1 UCSF GRCh37 15 76019491 76019491 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 158 109 206 0 ENST00000332145.2:c.435C>T p.Tyr145= p.Y145= ENST00000332145 NM_175881.3 145 taC/taT 0 +ODF3L2 UCSF GRCh37 19 463984 463984 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 20 36 0 ENST00000315489.4:c.730T>A p.Cys244Ser p.C244S ENST00000315489 NM_182577.2 244 Tgc/Agc 0 +ODZ1 UCSF GRCh37 X 123518169 123518169 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 75 86 0 ENST00000371130.3:c.6591C>T p.Asp2197= p.D2197= ENST00000371130 NM_014253.3 2197 gaC/gaT 0 +ODZ3 UCSF GRCh37 4 183676192 183676192 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 201 138 331 0 ENST00000511685.1:c.4672G>A p.Asp1558Asn p.D1558N ENST00000511685 1558 Gac/Aac 0 +ODZ4 UCSF GRCh37 11 78523317 78523317 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 22 60 0 ENST00000278550.7:c.1828G>A p.Gly610Ser p.G610S ENST00000278550 NM_001098816.2 610 Ggc/Agc 0 +OGFR UCSF GRCh37 20 61444910 61444910 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 32 85 0 ENST00000290291.6:c.1943G>A p.Gly648Glu p.G648E ENST00000290291 NM_007346.2 648 gGa/gAa 0 +OPLAH UCSF GRCh37 8 145114911 145114911 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 14 52 0 ENST00000426825.1:c.25C>T p.His9Tyr p.H9Y ENST00000426825 NM_017570.3 9 Cac/Tac 0 +OPRM1 UCSF GRCh37 6 154412611 154412611 + splice_region_variant,intron_variant Splice_Region SNP C C T snp132_rs79668187 P18_Rec Untested WXS Illumina HiSeq 68 45 107 0 ENST00000330432.7:c.1164+4C>T p.X388_splice ENST00000330432 NM_000914.3 0 +OPTN UCSF GRCh37 10 13152332 13152332 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 67 152 0 ENST00000263036.5:c.225G>A p.Trp75Ter p.W75* ENST00000263036 75 tgG/tgA 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 125 94 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR10H4 UCSF GRCh37 19 16059991 16059991 + synonymous_variant Silent SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 247 156 320 0 ENST00000322107.1:c.174A>G p.Thr58= p.T58= ENST00000322107 NM_001004465.1 58 acA/acG 0 +OR13C5 UCSF GRCh37 9 107361276 107361276 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 151 121 267 0 ENST00000374779.2:c.419C>T p.Ala140Val p.A140V ENST00000374779 NM_001004482.1 140 gCc/gTc 0 +OR1E1 UCSF GRCh37 17 3301584 3301584 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 130 81 228 0 ENST00000322608.2:c.121G>A p.Gly41Arg p.G41R ENST00000322608 NM_003553.2 41 Ggg/Agg 0 +OR1K1 UCSF GRCh37 9 125563103 125563103 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 53 116 0 ENST00000277309.2:c.702G>A p.Gly234= p.G234= ENST00000277309 NM_080859.1 234 ggG/ggA 0 +OR2A7 UCSF GRCh37 7 143955843 143955843 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 379 76 777 0 ENST00000493325.1:c.879C>A p.Asn293Lys p.N293K ENST00000493325 NM_001005328.1 293 aaC/aaA 0 +OR2B3 UCSF GRCh37 6 29054995 29054995 + stop_gained Nonsense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 59 104 0 ENST00000377173.2:c.31G>T p.Glu11Ter p.E11* ENST00000377173 NM_001005226.2 11 Gag/Tag 0 +OR2G2 UCSF GRCh37 1 247752168 247752168 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 154 113 201 0 ENST00000320065.1:c.507G>A p.Leu169= p.L169= ENST00000320065 NM_001001915.1 169 ctG/ctA 0 +OR2G3 UCSF GRCh37 1 247769095 247769095 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 215 167 345 0 ENST00000320002.2:c.208G>A p.Asp70Asn p.D70N ENST00000320002 NM_001001914.1 70 Gac/Aac 0 +OR2M7 UCSF GRCh37 1 248487743 248487743 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 166 324 0 ENST00000317965.2:c.128C>T p.Ser43Phe p.S43F ENST00000317965 NM_001004691.1 43 tCc/tTc 0 +OR2T27 UCSF GRCh37 1 248813649 248813649 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 32 108 0 ENST00000344889.3:c.537C>T p.Cys179= p.C179= ENST00000344889 NM_001001824.1 179 tgC/tgT 0 +OR4F6 UCSF GRCh37 15 102346758 102346758 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 72 150 0 ENST00000328882.4:c.836C>T p.Thr279Ile p.T279I ENST00000328882 NM_001005326.1 279 aCt/aTt 0 +OR4S2 UCSF GRCh37 11 55418984 55418984 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 169 131 251 0 ENST00000312422.2:c.605G>A p.Gly202Asp p.G202D ENST00000312422 NM_001004059.2 202 gGt/gAt 0 +OR51F1 UCSF GRCh37 11 4790433 4790433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 101 232 0 ENST00000380383.1:c.736G>A p.Val246Ile p.V246I ENST00000380383 246 Gtc/Atc 0 +OR51I1 UCSF GRCh37 11 5462162 5462162 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 39 119 0 ENST00000380211.1:c.583C>T p.His195Tyr p.H195Y ENST00000380211 NM_001005288.2 195 Cat/Tat 0 +OR56B1 UCSF GRCh37 11 5758081 5758081 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 71 125 0 ENST00000317121.3:c.335C>T p.Ala112Val p.A112V ENST00000317121 NM_001005180.2 112 gCc/gTc 0 +OR5B17 UCSF GRCh37 11 58125703 58125703 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 97 221 0 ENST00000357377.3:c.840C>T p.Ile280= p.I280= ENST00000357377 NM_001005489.1 280 atC/atT 0 +OR5B3 UCSF GRCh37 11 58170526 58170526 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 106 248 0 ENST00000309403.2:c.357C>T p.Asp119= p.D119= ENST00000309403 NM_001005469.1 119 gaC/gaT 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 185 110 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +OR5M10 UCSF GRCh37 11 56344312 56344312 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 230 161 343 0 ENST00000526812.2:c.886G>A p.Asp296Asn p.D296N ENST00000526812 NM_001004741.1 296 Gat/Aat 0 +OR5M9 UCSF GRCh37 11 56230263 56230263 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 58 126 0 ENST00000279791.1:c.615C>T p.Phe205= p.F205= ENST00000279791 NM_001004743.1 205 ttC/ttT 0 +OR6K2 UCSF GRCh37 1 158669593 158669593 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 73 161 0 ENST00000359610.2:c.850C>T p.Pro284Ser p.P284S ENST00000359610 NM_001005279.1 284 Ccc/Tcc 0 +OR6Y1 UCSF GRCh37 1 158517323 158517323 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 39 108 0 ENST00000302617.3:c.573C>T p.Asn191= p.N191= ENST00000302617 NM_001005189.1 191 aaC/aaT 0 +OR7G1 UCSF GRCh37 19 9226257 9226257 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 213 151 323 0 ENST00000541538.1:c.183C>T p.Phe61= p.F61= ENST00000541538 NM_001005192.2 61 ttC/ttT 0 +OR8G1 UCSF GRCh37 11 124120655 124120655 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 180 180 376 0 ENST00000341493.2:c.233C>T p.Thr78Ile p.T78I ENST00000341493 NM_001002905.1 78 aCc/aTc 0 +OR8G2 UCSF GRCh37 11 124095866 124095866 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 224 176 366 0 ENST00000366149.3:n.430C>T *144* ENST00000366149 0 +OR8G5 UCSF GRCh37 11 124135083 124135083 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 205 168 330 0 ENST00000524943.2:c.361G>A p.Val121Met p.V121M ENST00000524943 NM_001005198.1 121 Gtg/Atg 0 +ORC1 UCSF GRCh37 1 52859350 52859350 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 76 165 0 ENST00000371566.1:c.847C>T p.Leu283Phe p.L283F ENST00000371566 283 Ctt/Ttt 0 +ORC1 UCSF GRCh37 1 52850228 52850228 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 72 154 0 ENST00000371566.1:c.1749C>T p.Ile583= p.I583= ENST00000371566 583 atC/atT 0 +ORC4 UCSF GRCh37 2 148710093 148710093 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 51 176 0 ENST00000264169.2:c.437G>A p.Gly146Asp p.G146D ENST00000264169 NM_181742.3 146 gGt/gAt 0 +ORMDL2 UCSF GRCh37 12 56212905 56212905 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 52 141 0 ENST00000243045.5:c.122C>T p.Pro41Leu p.P41L ENST00000243045 NM_014182.4 41 cCc/cTc 0 +OTOGL UCSF GRCh37 12 80665526 80665526 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 125 248 0 ENST00000547103.1:c.2590C>T p.Leu864= p.L864= ENST00000547103 864 Cta/Tta 0 +OTOL1 UCSF GRCh37 3 161220824 161220824 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 35 87 0 ENST00000327928.4:c.528C>T p.Gly176= p.G176= ENST00000327928 NM_001080440.1 176 ggC/ggT 0 +OTOR UCSF GRCh37 20 16730562 16730562 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 47 35 72 0 ENST00000246081.2:c.270C>T p.Gly90= p.G90= ENST00000246081 NM_020157.3 90 ggC/ggT 0 +OTUD6B UCSF GRCh37 8 92090594 92090594 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 32 95 0 ENST00000404789.3:c.23C>T p.Ala8Val p.A8V ENST00000404789 NM_001286745.1 8 gCt/gTt 0 +OTUD7B UCSF GRCh37 1 149921614 149921614 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 53 106 0 ENST00000369135.4:c.1041C>T p.Arg347= p.R347= ENST00000369135 NM_020205.3 347 cgC/cgT 0 +OXCT1 UCSF GRCh37 5 41850167 41850167 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 45 122 0 ENST00000196371.5:c.529G>A p.Asp177Asn p.D177N ENST00000196371 NM_000436.3 177 Gat/Aat 0 +OXCT1 UCSF GRCh37 5 41803240 41803240 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 88 202 0 ENST00000196371.5:c.981C>T p.Leu327= p.L327= ENST00000196371 NM_000436.3 327 ctC/ctT 0 +OXCT1 UCSF GRCh37 5 41870383 41870383 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 20 53 0 ENST00000196371.5:c.78G>A p.Lys26= p.K26= ENST00000196371 NM_000436.3 26 aaG/aaA 0 +OXT UCSF GRCh37 20 3052734 3052734 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 8 8 0 ENST00000217386.2:c.132C>T p.Cys44= p.C44= ENST00000217386 NM_000915.3 44 tgC/tgT 0 +P2RX1 UCSF GRCh37 17 3808555 3808555 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 49 44 110 0 ENST00000225538.3:c.244C>T p.Pro82Ser p.P82S ENST00000225538 NM_002558.3 82 Ccc/Tcc 0 +P4HB UCSF GRCh37 17 79817154 79817154 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 64 161 0 ENST00000331483.4:c.255G>A p.Thr85= p.T85= ENST00000331483 NM_000918.3 85 acG/acA 0 +PACSIN1 UCSF GRCh37 6 34498080 34498080 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 30 29 51 0 ENST00000244458.2:c.849C>T p.Asp283= p.D283= ENST00000244458 283 gaC/gaT 0 +PACSIN1 UCSF GRCh37 6 34496419 34496419 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 88 149 0 ENST00000244458.2:c.221G>A p.Gly74Asp p.G74D ENST00000244458 74 gGc/gAc 0 +PADI4 UCSF GRCh37 1 17681089 17681089 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 67 134 0 ENST00000375448.4:c.1217C>T p.Ser406Phe p.S406F ENST00000375448 NM_012387.2 406 tCc/tTc 0 +PADI4 UCSF GRCh37 1 17668568 17668568 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 49 140 0 ENST00000375448.4:c.783C>T p.Phe261= p.F261= ENST00000375448 NM_012387.2 261 ttC/ttT 0 +PAF1 UCSF GRCh37 19 39880286 39880286 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 84 162 0 ENST00000221265.3:c.286C>T p.Pro96Ser p.P96S ENST00000221265 NM_019088.3 96 Ccc/Tcc 0 +PAFAH1B3 UCSF GRCh37 19 42804127 42804127 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 86 208 0 ENST00000262890.3:c.403G>A p.Val135Met p.V135M ENST00000262890 NM_002573.3 135 Gtg/Atg 0 +PAK2 UCSF GRCh37 3 196509539 196509539 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 186 128 250 0 ENST00000327134.3:c.22G>A p.Glu8Lys p.E8K ENST00000327134 NM_002577.4 8 Gaa/Aaa 0 +PALLD UCSF GRCh37 4 169847516 169847516 + downstream_gene_variant 3'Flank SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 69 135 0 ENST00000505667 0 +PALLD UCSF GRCh37 4 169632805 169632805 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 62 143 0 ENST00000505667.1:c.1695C>T p.Pro565= p.P565= ENST00000505667 565 ccC/ccT 0 +PANK2 UCSF GRCh37 20 3891437 3891437 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 99 274 0 ENST00000316562.4:c.1195G>A p.Val399Ile p.V399I ENST00000316562 NM_153638.2 399 Gta/Ata 0 +PAPL UCSF GRCh37 19 39590972 39590972 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 88 198 0 ENST00000331256.5:c.611G>A p.Gly204Glu p.G204E ENST00000331256 NM_001004318.2 204 gGg/gAg 0 +PAPLN UCSF GRCh37 14 73727430 73727430 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 15 36 0 ENST00000554301.1:c.1999C>T p.Pro667Ser p.P667S ENST00000554301 667 Cct/Tct 0 +PAPOLB UCSF GRCh37 7 4900571 4900571 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 209 174 338 0 ENST00000404991.1:c.868C>T p.Pro290Ser p.P290S ENST00000404991 NM_020144.4 290 Cct/Tct 0 +PAPOLG UCSF GRCh37 2 60987413 60987413 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 82 156 0 ENST00000238714.3:c.162G>A p.Glu54= p.E54= ENST00000238714 NM_022894.3 54 gaG/gaA 0 +PAQR6 UCSF GRCh37 1 156213739 156213739 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 128 224 0 ENST00000292291.5:c.*181G>A *61* ENST00000292291 NM_198406.2 0 +PARD3B UCSF GRCh37 2 205990383 205990383 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 169 113 221 0 ENST00000406610.2:c.1356G>A p.Met452Ile p.M452I ENST00000406610 NM_205863.3 452 atG/atA 0 +PARD6A UCSF GRCh37 16 67695000 67695000 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 34 59 0 ENST00000219255.3:c.59G>A p.Ser20Asn p.S20N ENST00000219255 20 aGc/aAc 0 +PARD6A UCSF GRCh37 16 67696373 67696373 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 33 84 0 ENST00000219255.3:c.864G>A p.Glu288= p.E288= ENST00000219255 288 gaG/gaA 0 +PARP3 UCSF GRCh37 3 51978176 51978176 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 120 248 0 ENST00000417220.2:c.255C>T p.Ile85= p.I85= ENST00000417220 85 atC/atT 0 +PARVA UCSF GRCh37 11 12399244 12399244 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 5 14 26 0 ENST00000334956.8:c.170C>T p.Pro57Leu p.P57L ENST00000334956 NM_018222.4 57 cCc/cTc 0 +PATL1 UCSF GRCh37 11 59418277 59418277 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 34 115 0 ENST00000300146.9:c.1534G>A p.Glu512Lys p.E512K ENST00000300146 NM_152716.2 512 Gaa/Aaa 0 +PAX6 UCSF GRCh37 11 31815068 31815068 + missense_variant Missense_Mutation SNP C C T snp132_rs75572362 P18_Rec Untested WXS Illumina HiSeq 101 102 199 0 ENST00000241001.8:c.950G>A p.Arg317Gln p.R317Q ENST00000241001 317 cGa/cAa 0 +PAX7 UCSF GRCh37 1 19062467 19062467 + intron_variant Intron SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 35 10 43 0 ENST00000420770.2:c.1402+95A>T *468* ENST00000420770 NM_001135254.1 0 +PAX8 UCSF GRCh37 2 114002114 114002114 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 174 112 265 0 ENST00000263334.5:c.279G>A p.Gly93= p.G93= ENST00000263334 93 ggG/ggA 0 +PBRM1 UCSF GRCh37 3 52702642 52702642 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 42 92 0 ENST00000296302.7:c.256G>A p.Glu86Lys p.E86K ENST00000296302 86 Gaa/Aaa 0 +PCBP2 UCSF GRCh37 12 53854828 53854828 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 79 142 0 ENST00000439930.3:c.405G>A p.Gly135= p.G135= ENST00000439930 135 ggG/ggA 0 +PCDH1 UCSF GRCh37 5 141248699 141248699 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 42 106 0 ENST00000394536.3:c.338C>T p.Thr113Ile p.T113I ENST00000394536 NM_002587.4 113 aCc/aTc 0 +PCDH12 UCSF GRCh37 5 141336753 141336753 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 75 141 0 ENST00000231484.3:c.664C>T p.Pro222Ser p.P222S ENST00000231484 NM_016580.3 222 Ccc/Tcc 0 +PCDH19 UCSF GRCh37 X 99661951 99661951 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 85 109 0 ENST00000373034.4:c.1645G>A p.Val549Met p.V549M ENST00000373034 NM_001184880.1 549 Gtg/Atg 0 +PCDHA5 UCSF GRCh37 5 140202528 140202528 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 127 93 217 0 ENST00000529859.1:c.1168C>T p.Pro390Ser p.P390S ENST00000529859 NM_018908.2 390 Ccc/Tcc 0 +PCDHB1 UCSF GRCh37 5 140432771 140432771 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 78 167 0 ENST00000306549.3:c.1716C>T p.Pro572= p.P572= ENST00000306549 NM_013340.2 572 ccC/ccT 0 +PCDHB16 UCSF GRCh37 5 140563139 140563139 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 77 177 0 ENST00000361016.2:c.1005G>A p.Leu335= p.L335= ENST00000361016 NM_020957.1 335 ctG/ctA 0 +PCDHB4 UCSF GRCh37 5 140503344 140503344 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 37 115 0 ENST00000194152.1:c.1764G>A p.Val588= p.V588= ENST00000194152 NM_018938.2 588 gtG/gtA 0 +PCDHB6 UCSF GRCh37 5 140531894 140531894 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 69 195 0 ENST00000231136.1:c.2056G>A p.Val686Ile p.V686I ENST00000231136 NM_018939.2 686 Gtc/Atc 0 +PCDHGA1 UCSF GRCh37 5 140711739 140711739 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 169 141 280 0 ENST00000517417.1:c.1488C>T p.Ile496= p.I496= ENST00000517417 NM_018912.2 496 atC/atT 0 +PCDHGA2 UCSF GRCh37 5 140719980 140719980 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 102 249 0 ENST00000394576.2:c.1442G>A p.Ser481Asn p.S481N ENST00000394576 NM_018915.2 481 aGc/aAc 0 +PCDHGA5 UCSF GRCh37 5 140744805 140744805 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 53 108 0 ENST00000518069.1:c.908C>T p.Thr303Ile p.T303I ENST00000518069 NM_018918.2 303 aCt/aTt 0 +PCDHGA8 UCSF GRCh37 5 140774817 140774817 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 178 120 246 0 ENST00000253812.6:c.2424+48793C>T *808* ENST00000253812 NM_018916.3 0 +PCDHGB1 UCSF GRCh37 5 140729999 140729999 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 46 112 0 ENST00000523390.1:c.172G>A p.Glu58Lys p.E58K ENST00000523390 NM_018922.2 58 Gag/Aag 0 +PCDHGB3 UCSF GRCh37 5 140751620 140751620 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 46 117 0 ENST00000576222.1:c.1659C>T p.Asp553= p.D553= ENST00000576222 NM_018924.2 553 gaC/gaT 0 +PCDHGB4 UCSF GRCh37 5 140768577 140768577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 83 212 0 ENST00000519479.1:c.1126C>T p.His376Tyr p.H376Y ENST00000519479 NM_003736.2 376 Cac/Tac 0 +PCDHGB6 UCSF GRCh37 5 140789820 140789820 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 74 202 0 ENST00000520790.1:c.2051C>T p.Pro684Leu p.P684L ENST00000520790 NM_018926.2 684 cCc/cTc 0 +PCDHGB7 UCSF GRCh37 5 140798542 140798542 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 155 116 272 0 ENST00000398594.2:c.1116G>A p.Arg372= p.R372= ENST00000398594 NM_018927.3 372 cgG/cgA 0 +PCDP1 UCSF GRCh37 2 120362768 120362768 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 53 130 0 ENST00000413369.3:c.1036G>A p.Gly346Ser p.G346S ENST00000413369 NM_001271049.1 346 Ggc/Agc 0 +PCF11 UCSF GRCh37 11 82875381 82875381 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 109 294 0 ENST00000298281.4:c.640C>T p.Gln214Ter p.Q214* ENST00000298281 NM_015885.3 214 Cag/Tag 0 +PCK2 UCSF GRCh37 14 24572399 24572399 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 24 51 0 ENST00000216780.4:c.1403G>A p.Trp468Ter p.W468* ENST00000216780 NM_004563.2 468 tGg/tAg 0 +PCK2 UCSF GRCh37 14 24572975 24572975 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 64 160 0 ENST00000216780.4:c.1725G>A p.Leu575= p.L575= ENST00000216780 NM_004563.2 575 ctG/ctA 0 +PCLO UCSF GRCh37 7 82583428 82583428 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 253 190 359 0 ENST00000333891.9:c.6841C>T p.Pro2281Ser p.P2281S ENST00000333891 NM_033026.5 2281 Cct/Tct 0 +PCLO UCSF GRCh37 7 82585868 82585868 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 254 159 408 0 ENST00000333891.9:c.4401G>A p.Glu1467= p.E1467= ENST00000333891 NM_033026.5 1467 gaG/gaA 0 +PCLO UCSF GRCh37 7 82579026 82579026 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 115 235 0 ENST00000333891.9:c.10878C>T p.Pro3626= p.P3626= ENST00000333891 NM_033026.5 3626 ccC/ccT 0 +PCNX UCSF GRCh37 14 71518672 71518672 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 97 200 0 ENST00000304743.2:c.4520G>A p.Ser1507Asn p.S1507N ENST00000304743 NM_014982.2 1507 aGt/aAt 0 +PCSK7 UCSF GRCh37 11 117079743 117079743 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 8 73 0 ENST00000320934.3:c.1561G>A p.Gly521Arg p.G521R ENST00000320934 NM_004716.2 521 Ggg/Agg 0 +PCSK7 UCSF GRCh37 11 117100424 117100424 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 26 30 65 0 ENST00000320934.3:c.137G>A p.Gly46Asp p.G46D ENST00000320934 NM_004716.2 46 gGc/gAc 0 +PCYOX1L UCSF GRCh37 5 148742296 148742296 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 111 78 188 0 ENST00000274569.4:c.185C>T p.Thr62Ile p.T62I ENST00000274569 NM_024028.3 62 aCc/aTc 0 +PDE1C UCSF GRCh37 7 31864559 31864559 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 175 112 274 0 ENST00000321453.7:c.1328C>T p.Thr443Met p.T443M ENST00000321453 NM_001191059.1 443 aCg/aTg 0 +PDE1C UCSF GRCh37 7 31887640 31887640 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 159 111 240 0 ENST00000321453.7:c.922C>T p.Leu308Phe p.L308F ENST00000321453 NM_001191059.1 308 Ctt/Ttt 0 +PDE2A UCSF GRCh37 11 72293528 72293528 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 50 118 0 ENST00000334456.5:c.1811C>T p.Thr604Ile p.T604I ENST00000334456 NM_002599.4 604 aCc/aTc 0 +PDE4D UCSF GRCh37 5 59284412 59284412 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 191 147 266 0 ENST00000502484.2:c.175G>A p.Ala59Thr p.A59T ENST00000502484 NM_001165899.1 59 Gct/Act 0 +PDE4DIP UCSF GRCh37 1 144879476 144879476 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 300 83 330 0 ENST00000369354.3:c.3974G>A p.Ser1325Asn p.S1325N ENST00000369354 1325 aGt/aAt 0 +PDE5A UCSF GRCh37 4 120422325 120422325 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 56 138 0 ENST00000354960.3:c.2490G>A p.Glu830= p.E830= ENST00000354960 NM_001083.3 830 gaG/gaA 0 +PDE6B UCSF GRCh37 4 657647 657647 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 20 29 0 ENST00000496514.1:c.2009C>T p.Ala670Val p.A670V ENST00000496514 670 gCc/gTc 0 +PDE6C UCSF GRCh37 10 95385407 95385407 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 53 85 0 ENST00000371447.3:c.939+1G>A p.X313_splice ENST00000371447 NM_006204.3 0 +PDE8A UCSF GRCh37 15 85664105 85664105 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 96 163 0 ENST00000310298.4:c.1812C>T p.Thr604= p.T604= ENST00000310298 604 acC/acT 0 +PDGFA UCSF GRCh37 7 551993 551993 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 20 63 0 ENST00000354513.5:c.260G>A p.Ser87Asn p.S87N ENST00000354513 NM_002607.5 87 aGc/aAc 0 +PDLIM3 UCSF GRCh37 4 186429600 186429600 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 79 168 0 ENST00000284770.5:c.515C>T p.Pro172Leu p.P172L ENST00000284770 NM_014476.5 172 cCt/cTt 0 +PDLIM7 UCSF GRCh37 5 176911158 176911158 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 50 118 0 ENST00000355841.2:c.1084G>A p.Val362Met p.V362M ENST00000355841 NM_005451.4 362 Gtg/Atg 0 +PDLIM7 UCSF GRCh37 5 176915113 176915113 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 75 134 0 ENST00000355841.2:c.1006C>T p.Arg336Cys p.R336C ENST00000355841 NM_005451.4 336 Cgc/Tgc 0 +PDZD2 UCSF GRCh37 5 32087729 32087729 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 40 100 0 ENST00000438447.1:c.4175C>T p.Ala1392Val p.A1392V ENST00000438447 1392 gCc/gTc 0 +PDZD2 UCSF GRCh37 5 31995702 31995702 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 54 141 0 ENST00000438447.1:c.999G>A p.Trp333Ter p.W333* ENST00000438447 333 tgG/tgA 0 +PEG3 UCSF GRCh37 19 57327800 57327800 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 155 106 227 0 ENST00000326441.9:c.2010G>A p.Gln670= p.Q670= ENST00000326441 NM_006210.2 670 caG/caA 0 +PELO UCSF GRCh37 5 52096954 52096954 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 71 142 0 ENST00000274311.2:c.726G>A p.Gln242= p.Q242= ENST00000274311 NM_015946.4 242 caG/caA 0 +PET112 UCSF GRCh37 4 152637283 152637283 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 43 110 0 ENST00000263985.6:c.641G>A p.Gly214Glu p.G214E ENST00000263985 NM_004564.2 214 gGa/gAa 0 +PEX13 UCSF GRCh37 2 61272904 61272904 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 71 168 0 ENST00000295030.5:c.831C>T p.Ala277= p.A277= ENST00000295030 NM_002618.3 277 gcC/gcT 0 +PEX14 UCSF GRCh37 1 10684432 10684432 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 66 127 0 ENST00000356607.4:c.523G>A p.Glu175Lys p.E175K ENST00000356607 NM_004565.2 175 Gag/Aag 0 +PEX5L UCSF GRCh37 3 179597794 179597794 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 68 141 0 ENST00000467460.1:c.428G>A p.Gly143Glu p.G143E ENST00000467460 NM_001256751.1 143 gGa/gAa 0 +PEX6 UCSF GRCh37 6 42936056 42936056 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 22 60 0 ENST00000304611.8:c.1660C>T p.Leu554Phe p.L554F ENST00000304611 NM_000287.3 554 Ctc/Ttc 0 +PFKM UCSF GRCh37 12 48536631 48536631 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 75 142 0 ENST00000312352.7:c.1720G>A p.Gly574Ser p.G574S ENST00000312352 NM_001166687.1 574 Ggt/Agt 0 +PGLS UCSF GRCh37 19 17628524 17628528 + frameshift_variant Frame_Shift_Del DEL GGAGA GGAGA - NOVEL P18_Rec Untested WXS Illumina HiSeq 49 0 ENST00000252603.2:c.504_508del p.Glu169AspfsTer7 p.E169Dfs*7 ENST00000252603 NM_012088.2 168 cgGGAGAag/cgag 0 +PGM3 UCSF GRCh37 6 83900605 83900605 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 82 191 0 ENST00000513973.1:c.127G>A p.Gly43Arg p.G43R ENST00000513973 NM_001199918.1 43 Gga/Aga 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 54 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PHF12 UCSF GRCh37 17 27233392 27233392 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 47 121 0 ENST00000332830.4:c.2824G>A p.Glu942Lys p.E942K ENST00000332830 NM_001033561.1 942 Gag/Aag 0 +PHF14 UCSF GRCh37 7 11022578 11022578 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 134 254 0 ENST00000403050.3:c.692G>A p.Gly231Glu p.G231E ENST00000403050 NM_014660.3 231 gGa/gAa 0 +PHF17 UCSF GRCh37 4 129783248 129783248 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 53 169 0 ENST00000226319.6:c.1371G>A p.Lys457= p.K457= ENST00000226319 NM_199320.2 457 aaG/aaA 0 +PHF6 UCSF GRCh37 X 133547969 133547969 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 106 126 0 ENST00000332070.3:c.702G>A p.Lys234= p.K234= ENST00000332070 NM_032458.2 234 aaG/aaA 0 +PHIP UCSF GRCh37 6 79650787 79650787 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 128 259 0 ENST00000275034.4:c.5089G>A p.Glu1697Lys p.E1697K ENST00000275034 NM_017934.5 1697 Gaa/Aaa 0 +PHKB UCSF GRCh37 16 47533749 47533749 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 131 114 245 0 ENST00000323584.5:c.249G>A p.Lys83= p.K83= ENST00000323584 NM_000293.2 83 aaG/aaA 0 +PHKG2 UCSF GRCh37 16 30767589 30767589 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 86 187 0 ENST00000563588.1:c.643G>A p.Asp215Asn p.D215N ENST00000563588 NM_000294.2 215 Gac/Aac 0 +PHOX2B UCSF GRCh37 4 41750393 41750393 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 29 102 0 ENST00000226382.2:c.235G>A p.Ala79Thr p.A79T ENST00000226382 NM_003924.3 79 Gcc/Acc 0 +PHRF1 UCSF GRCh37 11 606577 606577 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 22 65 0 ENST00000264555.5:c.1590C>T p.Ser530= p.S530= ENST00000264555 NM_020901.2 530 tcC/tcT 0 +PHTF2 UCSF GRCh37 7 77549735 77549735 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 200 130 300 0 ENST00000248550.7:c.916G>A p.Glu306Lys p.E306K ENST00000248550 306 Gaa/Aaa 0 +PHYHD1 UCSF GRCh37 9 131696310 131696310 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 59 108 0 ENST00000372592.3:c.289G>A p.Glu97Lys p.E97K ENST00000372592 NM_001100876.1 97 Gag/Aag 0 +PI4K2B UCSF GRCh37 4 25270136 25270136 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 58 115 0 ENST00000264864.6:c.1150C>T p.Pro384Ser p.P384S ENST00000264864 NM_018323.3 384 Cca/Tca 0 +PIAS1 UCSF GRCh37 15 68473593 68473593 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 186 147 297 0 ENST00000249636.6:c.1525C>T p.Pro509Ser p.P509S ENST00000249636 NM_016166.1 509 Cca/Tca 0 +PIDD UCSF GRCh37 11 799413 799413 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 53 112 0 ENST00000347755.5:c.2627G>A p.Gly876Asp p.G876D ENST00000347755 NM_145886.3 876 gGc/gAc 0 +PIEZO2 UCSF GRCh37 18 10680198 10680198 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 59 143 0 ENST00000503781.3:c.7611G>A p.Gln2537= p.Q2537= ENST00000503781 NM_022068.2 2537 caG/caA 0 +PIGL UCSF GRCh37 17 16221183 16221183 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 68 145 0 ENST00000225609.5:c.621C>T p.Val207= p.V207= ENST00000225609 NM_004278.3 207 gtC/gtT 0 +PIGO UCSF GRCh37 9 35095060 35095060 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 61 145 0 ENST00000378617.3:c.503C>T p.Thr168Ile p.T168I ENST00000378617 NM_032634.3 168 aCc/aTc 0 +PIGW UCSF GRCh37 17 34892953 34892953 + start_lost Translation_Start_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 54 148 0 ENST00000592983.1:c.3G>A p.Met1? p.M1? ENST00000592983 1 atG/atA 0 +PIK3CA UCSF GRCh37 3 178936082 178936082 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 76 58 158 0 ENST00000263967.3:c.1624G>A p.Glu542Lys p.E542K ENST00000263967 NM_006218.2 542 Gaa/Aaa 0 +PIK3CA UCSF GRCh37 3 178936076 178936076 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 70 57 153 0 ENST00000263967.3:c.1618C>G p.Leu540Val p.L540V ENST00000263967 NM_006218.2 540 Ctc/Gtc 0 +PIK3CD UCSF GRCh37 1 9775947 9775947 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 22 58 0 ENST00000377346.4:c.411C>T p.Asn137= p.N137= ENST00000377346 NM_005026.3 137 aaC/aaT 0 +PIK3R3 UCSF GRCh37 1 46532727 46532727 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 206 140 288 0 ENST00000262741.5:c.351C>T p.His117= p.H117= ENST00000262741 NM_003629.3 117 caC/caT 0 +PIK3R5 UCSF GRCh37 17 8791876 8791876 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 22 44 0 ENST00000447110.1:c.1228G>A p.Glu410Lys p.E410K ENST00000447110 NM_001251855.1 410 Gaa/Aaa 0 +PIKFYVE UCSF GRCh37 2 209214753 209214753 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 85 197 1 ENST00000264380.4:c.5380G>A p.Val1794Ile p.V1794I ENST00000264380 NM_015040.3 1794 Gta/Ata 0 +PILRB UCSF GRCh37 7 99956627 99956627 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 73 195 0 ENST00000452089.1:c.379G>A p.Val127Ile p.V127I ENST00000452089 127 Gtc/Atc 0 +PINX1 UCSF GRCh37 8 10623210 10623210 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 161 110 230 0 ENST00000314787.3:c.688C>T p.Pro230Ser p.P230S ENST00000314787 NM_017884.4 230 Cct/Tct 0 +PIP5KL1 UCSF GRCh37 9 130688199 130688199 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 34 77 0 ENST00000388747.4:c.710C>T p.Pro237Leu p.P237L ENST00000388747 NM_001135219.1 237 cCc/cTc 0 +PIWIL4 UCSF GRCh37 11 94341853 94341853 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 106 177 0 ENST00000299001.6:c.1943+1G>A p.X648_splice ENST00000299001 NM_152431.2 0 +PKD1 UCSF GRCh37 16 2160943 2160943 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 152 39 99 0 ENST00000262304.4:c.4225C>T p.Pro1409Ser p.P1409S ENST00000262304 NM_001009944.2 1409 Ccc/Tcc 0 +PKD1 UCSF GRCh37 16 2164604 2164604 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 8 16 0 ENST00000262304.4:c.2420C>T p.Ser807Phe p.S807F ENST00000262304 NM_001009944.2 807 tCc/tTc 0 +PKD1 UCSF GRCh37 16 2149911 2149911 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 34 69 0 ENST00000262304.4:c.9874C>T p.Leu3292= p.L3292= ENST00000262304 NM_001009944.2 3292 Ctg/Ttg 0 +PKD1 UCSF GRCh37 16 2159333 2159333 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 43 39 0 ENST00000262304.4:c.5835C>T p.Asp1945= p.D1945= ENST00000262304 NM_001009944.2 1945 gaC/gaT 0 +PKD2L1 UCSF GRCh37 10 102051073 102051073 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 64 191 0 ENST00000318222.3:c.1992C>T p.Asp664= p.D664= ENST00000318222 NM_016112.2 664 gaC/gaT 0 +PKHD1 UCSF GRCh37 6 51612952 51612952 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 219 170 363 0 ENST00000371117.3:c.9462C>T p.Asp3154= p.D3154= ENST00000371117 NM_138694.3 3154 gaC/gaT 0 +PLA2R1 UCSF GRCh37 2 160832690 160832690 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 47 115 0 ENST00000283243.7:c.2484C>T p.Thr828= p.T828= ENST00000283243 NM_001195641.1 828 acC/acT 0 +PLAGL1 UCSF GRCh37 6 144263210 144263210 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 69 152 0 ENST00000354765.2:c.743C>T p.Ala248Val p.A248V ENST00000354765 248 gCc/gTc 0 +PLAU UCSF GRCh37 10 75673360 75673360 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 180 138 301 0 ENST00000372764.3:c.524C>T p.Pro175Leu p.P175L ENST00000372764 NM_002658.3 175 cCc/cTc 0 +PLAUR UCSF GRCh37 19 44169538 44169538 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 68 155 0 ENST00000340093.3:c.240G>A p.Arg80= p.R80= ENST00000340093 NM_002659.3 80 cgG/cgA 0 +PLCB3 UCSF GRCh37 11 64030184 64030184 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 55 151 0 ENST00000279230.6:c.2259C>T p.Gly753= p.G753= ENST00000279230 753 ggC/ggT 0 +PLCD1 UCSF GRCh37 3 38050863 38050863 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 53 133 0 ENST00000334661.4:c.1506C>T p.Val502= p.V502= ENST00000334661 NM_006225.3 502 gtC/gtT 0 +PLCH1 UCSF GRCh37 3 155301352 155301352 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 100 197 0 ENST00000340059.7:c.644G>A p.Arg215Gln p.R215Q ENST00000340059 NM_001130960.1 215 cGa/cAa 0 +PLCL1 UCSF GRCh37 2 198950615 198950615 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 132 93 200 0 ENST00000428675.1:c.2374G>A p.Ala792Thr p.A792T ENST00000428675 NM_006226.3 792 Gcc/Acc 0 +PLCL1 UCSF GRCh37 2 198949378 198949378 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 170 121 257 0 ENST00000428675.1:c.1137G>A p.Gln379= p.Q379= ENST00000428675 NM_006226.3 379 caG/caA 0 +PLEC UCSF GRCh37 8 145007028 145007028 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 12 35 0 ENST00000322810.4:c.2081G>A p.Ser694Asn p.S694N ENST00000322810 NM_201380.2 694 aGc/aAc 0 +PLEC UCSF GRCh37 8 145010156 145010156 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 37 73 0 ENST00000322810.4:c.873G>A p.Gln291= p.Q291= ENST00000322810 NM_201380.2 291 caG/caA 0 +PLEC UCSF GRCh37 8 144992720 144992720 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 16 41 0 ENST00000322810.4:c.11680C>T p.Leu3894= p.L3894= ENST00000322810 NM_201380.2 3894 Ctg/Ttg 0 +PLEKHA6 UCSF GRCh37 1 204197900 204197900 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 59 113 0 ENST00000272203.3:c.2841G>A p.Lys947= p.K947= ENST00000272203 NM_014935.4 947 aaG/aaA 0 +PLEKHA6 UCSF GRCh37 1 204198137 204198137 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 41 89 0 ENST00000272203.3:c.2679C>T p.Pro893= p.P893= ENST00000272203 NM_014935.4 893 ccC/ccT 0 +PLEKHD1 UCSF GRCh37 14 69995020 69995020 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 9 31 0 ENST00000322564.7:c.1405G>A p.Glu469Lys p.E469K ENST00000322564 NM_001161498.1 469 Gag/Aag 0 +PLEKHG1 UCSF GRCh37 6 151130280 151130280 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 60 144 0 ENST00000358517.2:c.952C>T p.Leu318= p.L318= ENST00000358517 318 Ctg/Ttg 0 +PLEKHG6 UCSF GRCh37 12 6427914 6427914 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 30 88 0 ENST00000011684.7:c.1279G>A p.Asp427Asn p.D427N ENST00000011684 NM_018173.3 427 Gac/Aac 0 +PLEKHM2 UCSF GRCh37 1 16051828 16051828 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 6 26 0 ENST00000375799.3:c.729C>T p.Asp243= p.D243= ENST00000375799 NM_015164.2 243 gaC/gaT 0 +PLIN2 UCSF GRCh37 9 19121023 19121023 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 30 114 242 0 ENST00000276914.2:c.450G>A p.Glu150= p.E150= ENST00000276914 NM_001122.3 150 gaG/gaA 0 +PLIN4 UCSF GRCh37 19 4512632 4512632 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 195 145 329 0 ENST00000301286.3:c.1298C>T p.Ala433Val p.A433V ENST00000301286 NM_001080400.1 433 gCc/gTc 0 +PLK3 UCSF GRCh37 1 45270338 45270338 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 93 235 0 ENST00000372201.4:c.1522C>T p.Pro508Ser p.P508S ENST00000372201 NM_004073.2 508 Ccc/Tcc 0 +PLP2 UCSF GRCh37 X 49029528 49029528 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 41 60 0 ENST00000376327.5:c.149C>T p.Ser50Phe p.S50F ENST00000376327 NM_002668.2 50 tCc/tTc 0 +PLS1 UCSF GRCh37 3 142430816 142430816 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 186 155 291 0 ENST00000337777.3:c.1857C>T p.Cys619= p.C619= ENST00000337777 NM_002670.2 619 tgC/tgT 0 +PLSCR3 UCSF GRCh37 17 7296785 7296785 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 157 151 269 0 ENST00000535512.1:c.286+1G>A p.X96_splice ENST00000535512 0 +PLSCR4 UCSF GRCh37 3 145924492 145924492 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 34 62 0 ENST00000354952.2:c.175G>A p.Gly59Arg p.G59R ENST00000354952 NM_020353.2 59 Gga/Aga 0 +PLXDC2 UCSF GRCh37 10 20432236 20432236 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 303 94 230 0 ENST00000377252.4:c.554C>T p.Thr185Ile p.T185I ENST00000377252 NM_032812.7 185 aCt/aTt 0 +PLXNA2 UCSF GRCh37 1 208218062 208218062 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 17 64 0 ENST00000367033.3:c.3665C>T p.Ser1222Leu p.S1222L ENST00000367033 NM_025179.3 1222 tCg/tTg 0 +PLXNA2 UCSF GRCh37 1 208272261 208272261 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 26 58 0 ENST00000367033.3:c.1661C>T p.Ala554Val p.A554V ENST00000367033 NM_025179.3 554 gCc/gTc 0 +PLXNA2 UCSF GRCh37 1 208227865 208227865 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 51 77 0 ENST00000367033.3:c.2757C>T p.Gly919= p.G919= ENST00000367033 NM_025179.3 919 ggC/ggT 0 +PLXNB1 UCSF GRCh37 3 48462134 48462134 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 16 59 0 ENST00000296440.6:c.1968G>A p.Trp656Ter p.W656* ENST00000296440 NM_001130082.1 656 tgG/tgA 0 +PLXND1 UCSF GRCh37 3 129290040 129290040 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 55 48 126 0 ENST00000324093.4:c.3443A>G p.Asp1148Gly p.D1148G ENST00000324093 NM_015103.2 1148 gAc/gGc 0 +PML UCSF GRCh37 15 74325727 74325727 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 37 75 0 ENST00000268058.3:c.1629C>T p.Asn543= p.N543= ENST00000268058 NM_033238.2 543 aaC/aaT 0 +PMM1 UCSF GRCh37 22 41973821 41973821 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 55 139 0 ENST00000216259.7:c.657G>A p.Glu219= p.E219= ENST00000216259 NM_002676.2 219 gaG/gaA 0 +PNLIPRP3 UCSF GRCh37 10 118220511 118220511 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 125 69 189 0 ENST00000369230.3:c.599C>T p.Thr200Ile p.T200I ENST00000369230 NM_001011709.2 200 aCt/aTt 0 +POC1A UCSF GRCh37 3 52109984 52109984 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 76 171 0 ENST00000296484.2:c.1143G>A p.Glu381= p.E381= ENST00000296484 NM_015426.4 381 gaG/gaA 0 +POGK UCSF GRCh37 1 166810316 166810316 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 59 137 0 ENST00000367875.1:c.123G>A p.Glu41= p.E41= ENST00000367875 41 gaG/gaA 0 +POGZ UCSF GRCh37 1 151396657 151396657 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 108 184 0 ENST00000271715.2:c.1291C>T p.Pro431Ser p.P431S ENST00000271715 NM_015100.3 431 Cct/Tct 0 +POLA1 UCSF GRCh37 X 25014013 25014013 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 75 73 0 ENST00000379059.3:c.4335C>T p.Gly1445= p.G1445= ENST00000379059 NM_016937.3 1445 ggC/ggT 0 +POLD1 UCSF GRCh37 19 50905276 50905276 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 32 85 0 ENST00000440232.2:c.484G>T p.Gly162Cys p.G162C ENST00000440232 NM_002691.3 162 Ggt/Tgt 0 +POLDIP3 UCSF GRCh37 22 42988024 42988024 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 104 224 0 ENST00000252115.5:c.958G>A p.Val320Met p.V320M ENST00000252115 NM_001278657.1 320 Gtg/Atg 0 +POLH UCSF GRCh37 6 43582155 43582155 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 235 152 309 0 ENST00000372236.4:c.2003C>T p.Ser668Phe p.S668F ENST00000372236 NM_006502.2 668 tCt/tTt 0 +POLN UCSF GRCh37 4 2129915 2129915 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 203 141 308 1 ENST00000382865.1:c.1907C>T p.Ser636Phe p.S636F ENST00000382865 NM_181808.2 636 tCt/tTt 0 +POLN UCSF GRCh37 4 2159619 2159619 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 117 251 0 ENST00000382865.1:c.1631C>T p.Thr544Ile p.T544I ENST00000382865 NM_181808.2 544 aCc/aTc 0 +POLR1E UCSF GRCh37 9 37503132 37503132 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 65 166 0 ENST00000377792.3:c.1379C>T p.Thr460Ile p.T460I ENST00000377792 460 aCc/aTc 0 +POLR1E UCSF GRCh37 9 37486787 37486787 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 104 224 0 ENST00000377792.3:c.350G>A p.Arg117Lys p.R117K ENST00000377792 117 aGg/aAg 0 +POLR3A UCSF GRCh37 10 79745098 79745098 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 91 145 0 ENST00000372371.3:c.3072G>A p.Arg1024= p.R1024= ENST00000372371 NM_007055.3 1024 agG/agA 0 +POM121 UCSF GRCh37 7 72400590 72400590 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 190 141 339 0 ENST00000434423.2:c.1216C>T p.Pro406Ser p.P406S ENST00000434423 406 Cct/Tct 0 +POMZP3 UCSF GRCh37 7 76240803 76240803 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 100 149 0 ENST00000310842.4:c.543G>A p.Trp181Ter p.W181* ENST00000310842 NM_012230.3 181 tgG/tgA 0 +POU2F3 UCSF GRCh37 11 120139950 120139950 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 64 120 0 ENST00000543440.2:c.129G>A p.Arg43= p.R43= ENST00000543440 NM_014352.3 43 agG/agA 0 +POU3F1 UCSF GRCh37 1 38511573 38511573 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 44 91 0 ENST00000373012.2:c.843C>T p.Gly281= p.G281= ENST00000373012 NM_002699.3 281 ggC/ggT 0 +PPAPDC3 UCSF GRCh37 9 134165721 134165721 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 49 108 0 ENST00000372264.3:c.337G>A p.Val113Ile p.V113I ENST00000372264 NM_032728.3 113 Gtc/Atc 0 +PPARGC1A UCSF GRCh37 4 23826108 23826108 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 151 310 0 ENST00000264867.2:c.781C>T p.Pro261Ser p.P261S ENST00000264867 NM_013261.3 261 Cct/Tct 0 +PPARGC1B UCSF GRCh37 5 149214929 149214929 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 78 163 0 ENST00000309241.5:c.1807+1G>A p.X603_splice ENST00000309241 NM_133263.3 0 +PPEF2 UCSF GRCh37 4 76797592 76797592 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 42 26 79 0 ENST00000286719.7:c.1168G>A p.Val390Met p.V390M ENST00000286719 NM_006239.2 390 Gtg/Atg 0 +PPFIA1 UCSF GRCh37 11 70201767 70201767 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 81 141 0 ENST00000253925.7:c.2338C>T p.Pro780Ser p.P780S ENST00000253925 NM_003626.3 780 Ccc/Tcc 0 +PPIG UCSF GRCh37 2 170493450 170493450 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 94 197 0 ENST00000260970.3:c.1682G>A p.Arg561Lys p.R561K ENST00000260970 NM_004792.2 561 aGa/aAa 0 +PPIP5K1 UCSF GRCh37 15 43827298 43827298 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 103 209 0 ENST00000396923.3:c.3876C>T p.Asn1292= p.N1292= ENST00000396923 1292 aaC/aaT 0 +PPL UCSF GRCh37 16 4953973 4953973 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 21 64 0 ENST00000345988.2:c.231C>T p.Asp77= p.D77= ENST00000345988 NM_002705.4 77 gaC/gaT 0 +PPP1R13B UCSF GRCh37 14 104219354 104219354 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 62 141 0 ENST00000202556.9:c.811C>T p.Leu271= p.L271= ENST00000202556 NM_015316.2 271 Ctg/Ttg 0 +PPP1R15A UCSF GRCh37 19 49376632 49376632 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 29 62 0 ENST00000200453.5:c.142G>A p.Glu48Lys p.E48K ENST00000200453 NM_014330.3 48 Gaa/Aaa 0 +PPP1R16A UCSF GRCh37 8 145722709 145722709 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 23 49 0 ENST00000292539.4:c.132C>T p.Ala44= p.A44= ENST00000292539 44 gcC/gcT 0 +PPP1R3D UCSF GRCh37 20 58514666 58514666 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 27 6 20 0 ENST00000370996.3:c.321C>T p.Asp107= p.D107= ENST00000370996 NM_006242.3 107 gaC/gaT 0 +PPP2R5C UCSF GRCh37 14 102368190 102368190 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 57 153 0 ENST00000334743.5:c.987G>A p.Arg329= p.R329= ENST00000334743 NM_002719.3 329 cgG/cgA 0 +PPP3CB UCSF GRCh37 10 75230479 75230479 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 64 136 0 ENST00000360663.5:c.948G>A p.Ser316= p.S316= ENST00000360663 316 tcG/tcA 0 +PPP3CC UCSF GRCh37 8 22368658 22368658 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 135 96 200 0 ENST00000240139.5:c.544C>T p.Pro182Ser p.P182S ENST00000240139 NM_005605.4 182 Cct/Tct 0 +PPP6R2 UCSF GRCh37 22 50869666 50869666 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 58 188 0 ENST00000216061.5:c.1190C>T p.Ala397Val p.A397V ENST00000216061 397 gCt/gTt 0 +PPT1 UCSF GRCh37 1 40544268 40544268 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 66 177 0 ENST00000433473.3:c.690C>T p.Phe230= p.F230= ENST00000433473 NM_000310.3 230 ttC/ttT 0 +PRAMEF1 UCSF GRCh37 1 12854201 12854201 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 351 176 605 0 ENST00000332296.7:c.425G>A p.Gly142Glu p.G142E ENST00000332296 NM_023013.2 142 gGa/gAa 0 +PRAMEF12 UCSF GRCh37 1 12836049 12836049 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 156 114 239 0 ENST00000357726.4:c.651C>T p.Ser217= p.S217= ENST00000357726 NM_001080830.1 217 tcC/tcT 0 +PRAMEF4 UCSF GRCh37 1 12941966 12941966 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 105 301 0 ENST00000235349.5:c.584G>A p.Arg195His p.R195H ENST00000235349 NM_001009611.2 195 cGc/cAc 0 +PRAMEF6 UCSF GRCh37 1 13001251 13001251 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 420 108 732 0 ENST00000376189.1:c.432G>A p.Gln144= p.Q144= ENST00000376189 NM_001010889.2 144 caG/caA 0 +PRAMEF7 UCSF GRCh37 1 12979697 12979697 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 45 235 0 ENST00000330881.5:c.889G>A p.Val297Ile p.V297I ENST00000330881 NM_001012277.1 297 Gtc/Atc 0 +PRB4 UCSF GRCh37 12 11461546 11461546 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 214 69 289 0 ENST00000279575.1:c.371C>T p.Pro124Leu p.P124L ENST00000279575 NM_001261399.1 124 cCc/cTc 0 +PRDM10 UCSF GRCh37 11 129814713 129814713 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 114 85 190 0 ENST00000358825.5:c.715C>T p.Pro239Ser p.P239S ENST00000358825 NM_020228.2 239 Cct/Tct 0 +PRDM15 UCSF GRCh37 21 43221771 43221771 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 38 104 0 ENST00000269844.3:c.4153C>T p.Leu1385Phe p.L1385F ENST00000269844 NM_022115.3 1385 Ctc/Ttc 0 +PRDM15 UCSF GRCh37 21 43258105 43258105 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 76 202 0 ENST00000269844.3:c.2037G>A p.Arg679= p.R679= ENST00000269844 NM_022115.3 679 cgG/cgA 0 +PRDM16 UCSF GRCh37 1 3334421 3334421 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 97 177 0 ENST00000270722.5:c.2721G>A p.Lys907= p.K907= ENST00000270722 907 aaG/aaA 0 +PRDM2 UCSF GRCh37 1 14106287 14106287 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 70 148 0 ENST00000235372.7:c.1997G>A p.Ser666Asn p.S666N ENST00000235372 NM_012231.4 666 aGt/aAt 0 +PRDM2 UCSF GRCh37 1 14106776 14106776 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 80 180 0 ENST00000235372.7:c.2486G>A p.Gly829Asp p.G829D ENST00000235372 NM_012231.4 829 gGt/gAt 0 +PRDM4 UCSF GRCh37 12 108147759 108147759 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 47 98 0 ENST00000228437.5:c.273C>T p.Thr91= p.T91= ENST00000228437 NM_012406.3 91 acC/acT 0 +PRDX2 UCSF GRCh37 19 12911811 12911811 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 33 72 0 ENST00000301522.2:c.176G>A p.Ser59Asn p.S59N ENST00000301522 NM_005809.5 59 aGc/aAc 0 +PREX2 UCSF GRCh37 8 69017553 69017553 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 61 151 0 ENST00000288368.4:c.2716-2791C>T *906* ENST00000288368 NM_024870.2 0 +PRG4 UCSF GRCh37 1 186276020 186276020 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 63 126 0 ENST00000445192.2:c.1169C>T p.Pro390Leu p.P390L ENST00000445192 NM_005807.3 390 cCc/cTc 0 +PRIC285 UCSF GRCh37 20 62191299 62191299 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 25 56 0 ENST00000467148.1:c.7807G>A p.Glu2603Lys p.E2603K ENST00000467148 NM_001037335.2 2603 Gag/Aag 0 +PRIM2 UCSF GRCh37 6 57398214 57398214 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 428 114 714 1 ENST00000607273.1:c.917G>A p.Arg306Gln p.R306Q ENST00000607273 NM_000947.3 306 cGa/cAa 0 +PRKACG UCSF GRCh37 9 71628387 71628387 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 43 110 0 ENST00000377276.2:c.622C>T p.Pro208Ser p.P208S ENST00000377276 NM_002732.3 208 Ccc/Tcc 0 +PRKAG2 UCSF GRCh37 7 151573591 151573591 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 28 49 1 ENST00000287878.4:c.114+1G>A p.X38_splice ENST00000287878 NM_016203.3 0 +PRKCH UCSF GRCh37 14 61857951 61857951 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0014 P18_Rec Untested WXS Illumina HiSeq 75 67 130 0 ENST00000332981.5:c.372C>T p.Leu124= p.L124= ENST00000332981 NM_006255.3 124 ctC/ctT 0 +PRKCSH UCSF GRCh37 19 11552127 11552127 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 67 217 0 ENST00000589838.1:c.423G>A p.Lys141= p.K141= ENST00000589838 141 aaG/aaA 0 +PRKD1 UCSF GRCh37 14 30100122 30100122 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 90 179 0 ENST00000331968.5:c.1498G>A p.Val500Met p.V500M ENST00000331968 NM_002742.2 500 Gtg/Atg 0 +PRKD2 UCSF GRCh37 19 47195006 47195006 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 72 150 0 ENST00000291281.4:c.1688G>A p.Gly563Glu p.G563E ENST00000291281 563 gGa/gAa 0 +PRKD2 UCSF GRCh37 19 47204305 47204305 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 55 83 0 ENST00000291281.4:c.954C>T p.Ala318= p.A318= ENST00000291281 318 gcC/gcT 0 +PRMT10 UCSF GRCh37 4 148604985 148604985 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 41 108 0 ENST00000322396.6:c.154C>T p.Leu52Phe p.L52F ENST00000322396 NM_138364.2 52 Ctc/Ttc 0 +PRMT6 UCSF GRCh37 1 107600343 107600343 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 29 83 1 ENST00000370078.1:c.1006G>A p.Asp336Asn p.D336N ENST00000370078 336 Gac/Aac 0 +PRMT7 UCSF GRCh37 16 68380067 68380067 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 71 159 0 ENST00000339507.5:c.1075G>A p.Val359Ile p.V359I ENST00000339507 359 Gtc/Atc 0 +PROKR2 UCSF GRCh37 20 5294982 5294982 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 61 130 0 ENST00000217270.3:c.34C>T p.Pro12Ser p.P12S ENST00000217270 NM_144773.2 12 Ccc/Tcc 0 +PROL1 UCSF GRCh37 4 71275570 71275570 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 71 194 0 ENST00000399575.2:c.525C>T p.Ile175= p.I175= ENST00000399575 NM_021225.4 175 atC/atT 0 +PROM2 UCSF GRCh37 2 95941741 95941741 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 16 29 0 ENST00000317620.9:c.358G>A p.Val120Met p.V120M ENST00000317620 NM_001165978.1 120 Gtg/Atg 0 +PRPF19 UCSF GRCh37 11 60665699 60665699 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 60 137 0 ENST00000227524.4:c.1185C>T p.Ile395= p.I395= ENST00000227524 NM_014502.4 395 atC/atT 0 +PRPF31 UCSF GRCh37 19 54634839 54634839 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 48 99 0 ENST00000321030.4:c.1476G>A p.Glu492= p.E492= ENST00000321030 NM_015629.3 492 gaG/gaA 0 +PRPH2 UCSF GRCh37 6 42689649 42689649 + missense_variant Missense_Mutation SNP G G A snp132_rs61755783 P18_Rec Untested WXS Illumina HiSeq 83 89 162 0 ENST00000230381.5:c.424C>T p.Arg142Trp p.R142W ENST00000230381 NM_000322.4 142 Cgg/Tgg 0 +PRR13 UCSF GRCh37 12 53837352 53837352 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 7 25 90 0 ENST00000429243.2:c.197C>T p.Pro66Leu p.P66L ENST00000429243 NM_018457.3 66 cCa/cTa 0 +PRR14 UCSF GRCh37 16 30664424 30664424 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 42 85 0 ENST00000300835.4:c.504G>A p.Glu168= p.E168= ENST00000300835 NM_024031.2 168 gaG/gaA 0 +PRR14L UCSF GRCh37 22 32111480 32111480 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 129 308 0 ENST00000327423.6:c.2345C>T p.Ser782Phe p.S782F ENST00000327423 NM_173566.2 782 tCt/tTt 0 +PRR3 UCSF GRCh37 6 30529888 30529888 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 73 205 0 ENST00000376560.3:c.447C>T p.Pro149= p.P149= ENST00000376560 NM_025263.3 149 ccC/ccT 0 +PRRC2A UCSF GRCh37 6 31599022 31599022 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 102 73 164 0 ENST00000376007.4:c.2572G>A p.Glu858Lys p.E858K ENST00000376007 NM_080686.2 858 Gaa/Aaa 0 +PRRC2B UCSF GRCh37 9 134350096 134350096 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 62 141 0 ENST00000357304.4:c.2580C>T p.Val860= p.V860= ENST00000357304 NM_013318.3 860 gtC/gtT 0 +PRRC2B UCSF GRCh37 9 134362554 134362554 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 45 95 0 ENST00000357304.4:c.5857G>A p.Ala1953Thr p.A1953T ENST00000357304 NM_013318.3 1953 Gcc/Acc 0 +PRRC2C UCSF GRCh37 1 171519286 171519286 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 147 114 237 0 ENST00000338920.4:c.5028G>A p.Leu1676= p.L1676= ENST00000338920 NM_015172.3 1676 ttG/ttA 0 +PRRT2 UCSF GRCh37 16 29824379 29824379 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 44 91 0 ENST00000358758.7:c.4G>A p.Ala2Thr p.A2T ENST00000358758 NM_001256442.1 2 Gca/Aca 0 +PRSS1 UCSF GRCh37 7 142460858 142460858 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 173 107 209 0 ENST00000311737.7:c.731C>T p.Ala244Val p.A244V ENST00000311737 NM_002769.4 244 gCt/gTt 0 +PRSS21 UCSF GRCh37 16 2871579 2871579 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 50 106 0 ENST00000005995.3:c.918G>A p.Trp306Ter p.W306* ENST00000005995 306 tgG/tgA 0 +PRSS27 UCSF GRCh37 16 2763685 2763685 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 27 92 0 ENST00000302641.3:c.523C>T p.Pro175Ser p.P175S ENST00000302641 NM_031948.3 175 Ccg/Tcg 0 +PRSS36 UCSF GRCh37 16 31160803 31160803 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 34 105 1 ENST00000268281.4:c.90G>A p.Gln30= p.Q30= ENST00000268281 NM_173502.4 30 caG/caA 0 +PRSS48 UCSF GRCh37 4 152203454 152203454 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 180 327 0 ENST00000455694.2:c.370G>A p.Val124Ile p.V124I ENST00000455694 NM_183375.2 124 Gtc/Atc 0 +PSAP UCSF GRCh37 10 73594165 73594165 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 42 69 0 ENST00000394936.3:c.138G>A p.Lys46= p.K46= ENST00000394936 46 aaG/aaA 0 +PSAP UCSF GRCh37 10 73579249 73579249 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 48 143 0 ENST00000394936.3:c.1323C>T p.Ser441= p.S441= ENST00000394936 441 agC/agT 0 +PSD2 UCSF GRCh37 5 139219697 139219697 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 54 122 0 ENST00000274710.3:c.2054G>A p.Gly685Asp p.G685D ENST00000274710 NM_032289.2 685 gGc/gAc 0 +PSD3 UCSF GRCh37 8 18413857 18413857 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 113 242 0 ENST00000440756.2:c.2796G>A p.Glu932= p.E932= ENST00000440756 932 gaG/gaA 0 +PSD4 UCSF GRCh37 2 113953307 113953307 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 59 160 0 ENST00000245796.6:c.2185C>T p.Leu729Phe p.L729F ENST00000245796 NM_012455.2 729 Ctc/Ttc 0 +PSEN1 UCSF GRCh37 14 73683941 73683941 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 95 169 0 ENST00000324501.5:c.1237G>A p.Ala413Thr p.A413T ENST00000324501 NM_000021.3 413 Gcc/Acc 0 +PSMB1 UCSF GRCh37 6 170858151 170858151 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 61 108 0 ENST00000262193.6:c.164C>T p.Thr55Ile p.T55I ENST00000262193 NM_002793.3 55 aCt/aTt 0 +PSMB8 UCSF GRCh37 6 32809339 32809339 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 144 101 213 0 ENST00000374882.3:c.711C>T p.His237= p.H237= ENST00000374882 NM_148919.3 237 caC/caT 0 +PSMC1 UCSF GRCh37 14 90725515 90725515 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 43 118 0 ENST00000261303.8:c.15G>A p.Gln5= p.Q5= ENST00000261303 NM_002802.2 5 caG/caA 0 +PTBP1 UCSF GRCh37 19 806408 806408 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 21 19 0 ENST00000349038.4:c.893G>A p.Gly298Asp p.G298D ENST00000349038 NM_031991.3 298 gGc/gAc 0 +PTCHD1 UCSF GRCh37 X 23410906 23410906 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 143 151 1 ENST00000379361.4:c.1271G>A p.Ser424Asn p.S424N ENST00000379361 NM_173495.2 424 aGc/aAc 0 +PTCHD2 UCSF GRCh37 1 11579791 11579791 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 67 139 0 ENST00000294484.6:c.2054G>A p.Gly685Glu p.G685E ENST00000294484 NM_020780.1 685 gGa/gAa 0 +PTCRA UCSF GRCh37 6 42890938 42890938 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 70 155 0 ENST00000304672.1:c.232C>T p.Pro78Ser p.P78S ENST00000304672 NM_001243168.1 78 Cct/Tct 0 +PTDSS2 UCSF GRCh37 11 489641 489641 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 5 9 26 0 ENST00000308020.5:c.1023C>T p.Pro341= p.P341= ENST00000308020 NM_030783.1 341 ccC/ccT 0 +PTGS2 UCSF GRCh37 1 186647536 186647536 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 42 145 0 ENST00000367468.5:c.314C>T p.Ser105Phe p.S105F ENST00000367468 NM_000963.2 105 tCc/tTc 0 +PTPN12 UCSF GRCh37 7 77247874 77247874 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 106 226 0 ENST00000248594.6:c.1017G>A p.Arg339= p.R339= ENST00000248594 NM_002835.3 339 agG/agA 0 +PTPN13 UCSF GRCh37 4 87706518 87706518 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 77 57 115 0 ENST00000411767.2:c.6253C>T p.Pro2085Ser p.P2085S ENST00000411767 2085 Cca/Tca 0 +PTPN13 UCSF GRCh37 4 87732259 87732259 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 53 115 0 ENST00000411767.2:c.7360G>A p.Glu2454Lys p.E2454K ENST00000411767 2454 Gag/Aag 0 +PTPN14 UCSF GRCh37 1 214557113 214557113 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 42 39 94 0 ENST00000366956.5:c.2085G>A p.Lys695= p.K695= ENST00000366956 NM_005401.4 695 aaG/aaA 0 +PTPN23 UCSF GRCh37 3 47449443 47449443 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 19 47 0 ENST00000265562.4:c.1182G>A p.Leu394= p.L394= ENST00000265562 NM_015466.2 394 ctG/ctA 0 +PTPRA UCSF GRCh37 20 2968684 2968684 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 147 121 265 0 ENST00000380393.3:c.534G>A p.Lys178= p.K178= ENST00000380393 NM_002836.3 178 aaG/aaA 0 +PTPRD UCSF GRCh37 9 8518354 8518354 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 97 147 0 ENST00000356435.5:c.1037G>A p.Gly346Glu p.G346E ENST00000356435 346 gGg/gAg 0 +PTPRK UCSF GRCh37 6 128302298 128302298 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 44 104 0 ENST00000368215.3:c.3671G>A p.Gly1224Glu p.G1224E ENST00000368215 1224 gGg/gAg 0 +PTPRM UCSF GRCh37 18 7955142 7955142 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 45 149 0 ENST00000332175.8:c.862C>T p.Pro288Ser p.P288S ENST00000332175 NM_002845.3 288 Cct/Tct 0 +PTPRN UCSF GRCh37 2 220155002 220155002 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 23 55 0 ENST00000295718.2:c.2886C>T p.Ala962= p.A962= ENST00000295718 NM_002846.3 962 gcC/gcT 0 +PTPRT UCSF GRCh37 20 40790034 40790034 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 61 145 0 ENST00000373187.1:c.2640G>A p.Gln880= p.Q880= ENST00000373187 880 caG/caA 0 +PTPRZ1 UCSF GRCh37 7 121653306 121653306 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 105 234 0 ENST00000393386.2:c.4206G>A p.Leu1402= p.L1402= ENST00000393386 NM_001206838.1 1402 ctG/ctA 0 +PUF60 UCSF GRCh37 8 144898928 144898928 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 104 180 0 ENST00000526683.1:c.1442G>A p.Gly481Glu p.G481E ENST00000526683 NM_001271098.1 481 gGg/gAg 0 +PVRL3 UCSF GRCh37 3 110830999 110830999 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 75 191 0 ENST00000485303.1:c.283C>T p.His95Tyr p.H95Y ENST00000485303 NM_001243286.1 95 Cat/Tat 0 +PWP2 UCSF GRCh37 21 45542135 45542135 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 80 160 0 ENST00000291576.7:c.1714C>T p.Pro572Ser p.P572S ENST00000291576 NM_005049.2 572 Cct/Tct 0 +PWP2 UCSF GRCh37 21 45535238 45535238 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 86 189 0 ENST00000291576.7:c.564G>A p.Lys188= p.K188= ENST00000291576 NM_005049.2 188 aaG/aaA 0 +PXDN UCSF GRCh37 2 1670193 1670193 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 6 25 55 0 ENST00000252804.4:c.1084G>A p.Glu362Lys p.E362K ENST00000252804 NM_012293.1 362 Gag/Aag 0 +PYGM UCSF GRCh37 11 64514753 64514753 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 38 126 0 ENST00000164139.3:c.2255C>T p.Ser752Phe p.S752F ENST00000164139 NM_005609.2 752 tCc/tTc 0 +PYHIN1 UCSF GRCh37 1 158906715 158906715 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 65 133 0 ENST00000368140.1:c.15C>T p.Tyr5= p.Y5= ENST00000368140 NM_152501.4 5 taC/taT 0 +PYHIN1 UCSF GRCh37 1 158946491 158946491 + splice_region_variant,3_prime_UTR_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 140 80 198 0 ENST00000368140.1:c.*6G>A p.X2_splice ENST00000368140 NM_152501.4 0 +PYROXD2 UCSF GRCh37 10 100143560 100143560 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 131 93 201 0 ENST00000370575.4:c.1741A>G p.Met581Val p.M581V ENST00000370575 NM_032709.2 581 Atg/Gtg 0 +RAB11FIP5 UCSF GRCh37 2 73316440 73316440 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 97 184 0 ENST00000258098.6:c.435G>A p.Trp145Ter p.W145* ENST00000258098 NM_015470.2 145 tgG/tgA 0 +RAB18 UCSF GRCh37 10 27821451 27821451 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 315 128 219 0 ENST00000356940.6:c.202G>A p.Glu68Lys p.E68K ENST00000356940 NM_001256410.1 68 Gag/Aag 0 +RAB19 UCSF GRCh37 7 140125911 140125911 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 52 132 0 ENST00000356407.3:c.615G>A p.Met205Ile p.M205I ENST00000356407 205 atG/atA 0 +RAB20 UCSF GRCh37 13 111176438 111176438 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 52 128 0 ENST00000267328.3:c.279C>T p.Asp93= p.D93= ENST00000267328 NM_017817.1 93 gaC/gaT 0 +RAB26 UCSF GRCh37 16 2198927 2198927 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 7 15 11 0 ENST00000210187.6:c.143C>T p.Pro48Leu p.P48L ENST00000210187 NM_014353.4 48 cCc/cTc 0 +RAB3D UCSF GRCh37 19 11446138 11446138 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 35 62 0 ENST00000222120.3:c.457C>T p.Leu153Phe p.L153F ENST00000222120 NM_004283.3 153 Ctc/Ttc 0 +RAB40AL UCSF GRCh37 X 102192759 102192759 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 49 77 0 ENST00000218249.5:c.513C>T p.Ala171= p.A171= ENST00000218249 NM_001031834.1 171 gcC/gcT 0 +RAD1 UCSF GRCh37 5 34908987 34908987 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 113 245 0 ENST00000341754.4:c.732G>A p.Arg244= p.R244= ENST00000341754 244 cgG/cgA 0 +RAD18 UCSF GRCh37 3 8940731 8940731 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 193 56 105 0 ENST00000264926.2:c.1169G>A p.Gly390Glu p.G390E ENST00000264926 NM_020165.3 390 gGa/gAa 0 +RAD9B UCSF GRCh37 12 110960024 110960024 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 98 217 0 ENST00000392672.4:c.933C>T p.Gly311= p.G311= ENST00000392672 NM_152442.3 311 ggC/ggT 0 +RAET1E UCSF GRCh37 6 150210512 150210512 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 55 128 0 ENST00000357183.4:c.594G>A p.Gly198= p.G198= ENST00000357183 NM_139165.2 198 ggG/ggA 0 +RAI1 UCSF GRCh37 17 17697865 17697865 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 52 94 0 ENST00000353383.1:c.1603G>A p.Ala535Thr p.A535T ENST00000353383 NM_030665.3 535 Gcc/Acc 0 +RALA UCSF GRCh37 7 39726287 39726287 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 64 158 0 ENST00000005257.2:c.21G>A p.Lys7= p.K7= ENST00000005257 NM_005402.3 7 aaG/aaA 0 +RANBP17 UCSF GRCh37 5 170640635 170640635 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 132 76 151 0 ENST00000523189.1:c.2232G>A p.Met744Ile p.M744I ENST00000523189 NM_022897.3 744 atG/atA 0 +RANBP2 UCSF GRCh37 2 109398766 109398766 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 130 115 253 0 ENST00000283195.6:c.8943G>A p.Val2981= p.V2981= ENST00000283195 NM_006267.4 2981 gtG/gtA 0 +RANBP2 UCSF GRCh37 2 109392223 109392223 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 84 221 0 ENST00000283195.6:c.8328C>T p.Asp2776= p.D2776= ENST00000283195 NM_006267.4 2776 gaC/gaT 0 +RANBP2 UCSF GRCh37 2 109382380 109382380 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 132 90 216 0 ENST00000283195.6:c.5385G>A p.Glu1795= p.E1795= ENST00000283195 NM_006267.4 1795 gaG/gaA 0 +RAP1GAP2 UCSF GRCh37 17 2901517 2901517 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 193 123 291 0 ENST00000254695.8:c.1047C>T p.Leu349= p.L349= ENST00000254695 NM_015085.4 349 ctC/ctT 0 +RAP1GDS1 UCSF GRCh37 4 99264359 99264359 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 113 106 177 1 ENST00000408927.3:c.182A>C p.Gln61Pro p.Q61P ENST00000408927 NM_021159.4 61 cAg/cCg 0 +RAPGEF1 UCSF GRCh37 9 134463203 134463203 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 52 104 0 ENST00000372189.3:c.2595G>A p.Leu865= p.L865= ENST00000372189 NM_005312.2 865 ttG/ttA 0 +RAPGEF2 UCSF GRCh37 4 160277170 160277170 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 20 62 0 ENST00000264431.4:c.4334C>T p.Ala1445Val p.A1445V ENST00000264431 NM_014247.2 1445 gCt/gTt 0 +RAPH1 UCSF GRCh37 2 204304764 204304764 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 56 118 0 ENST00000319170.5:c.3149C>T p.Ala1050Val p.A1050V ENST00000319170 NM_213589.1 1050 gCc/gTc 0 +RAPH1 UCSF GRCh37 2 204306084 204306084 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 17 23 0 ENST00000319170.5:c.1829C>T p.Ser610Phe p.S610F ENST00000319170 NM_213589.1 610 tCc/tTc 0 +RASAL1 UCSF GRCh37 12 113573235 113573235 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 16 16 0 ENST00000261729.5:c.33G>A p.Val11= p.V11= ENST00000261729 11 gtG/gtA 0 +RAVER2 UCSF GRCh37 1 65278515 65278515 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 60 117 0 ENST00000294428.3:c.1775C>T p.Pro592Leu p.P592L ENST00000294428 592 cCc/cTc 0 +RBCK1 UCSF GRCh37 20 390563 390563 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 82 208 0 ENST00000356286.5:c.61G>A p.Gly21Ser p.G21S ENST00000356286 NM_031229.2 21 Ggc/Agc 0 +RBFOX1 UCSF GRCh37 16 7568257 7568257 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 208 92 195 0 ENST00000547338.1:c.136C>T p.Pro46Ser p.P46S ENST00000547338 NM_001142334.1 46 Ccc/Tcc 0 +RBM12 UCSF GRCh37 20 34241744 34241744 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 200 141 280 0 ENST00000359646.1:c.1501C>T p.Gln501Ter p.Q501* ENST00000359646 501 Caa/Taa 0 +RBM14 UCSF GRCh37 11 66392770 66392770 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 126 103 192 0 ENST00000310137.4:c.1423G>A p.Gly475Arg p.G475R ENST00000310137 NM_006328.3 475 Ggg/Agg 0 +RBM15 UCSF GRCh37 1 110883854 110883854 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 38 67 0 ENST00000369784.3:c.1827G>A p.Glu609= p.E609= ENST00000369784 NM_022768.4 609 gaG/gaA 0 +RBM19 UCSF GRCh37 12 114377894 114377894 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 56 153 0 ENST00000261741.5:c.1809G>A p.Leu603= p.L603= ENST00000261741 NM_016196.3 603 ctG/ctA 0 +RBM26 UCSF GRCh37 13 79932554 79932554 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 36 115 0 ENST00000438737.2:c.1544G>A p.Arg515Lys p.R515K ENST00000438737 NM_001286631.1 515 aGa/aAa 0 +RBMS2 UCSF GRCh37 12 56975264 56975264 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 25 54 113 0 ENST00000262031.5:c.704G>A p.Gly235Glu p.G235E ENST00000262031 NM_002898.3 235 gGa/gAa 0 +RBP3 UCSF GRCh37 10 48388215 48388215 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 26 71 0 ENST00000224600.4:c.2663C>T p.Pro888Leu p.P888L ENST00000224600 NM_002900.2 888 cCc/cTc 0 +RBPJL UCSF GRCh37 20 43942178 43942178 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 22 44 0 ENST00000343694.3:c.690C>T p.Tyr230= p.Y230= ENST00000343694 NM_001281449.1 230 taC/taT 0 +RCOR1 UCSF GRCh37 14 103188554 103188554 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 78 186 0 ENST00000570597.1:c.1211C>T p.Ala404Val p.A404V ENST00000570597 404 gCa/gTa 0 +RDX UCSF GRCh37 11 110124675 110124675 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 65 142 0 ENST00000343115.4:c.955G>A p.Glu319Lys p.E319K ENST00000343115 NM_001260494.1 319 Gaa/Aaa 0 +RECK UCSF GRCh37 9 36112353 36112353 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 61 112 0 ENST00000377966.3:c.1940G>A p.Gly647Glu p.G647E ENST00000377966 NM_021111.2 647 gGg/gAg 0 +RECK UCSF GRCh37 9 36118754 36118754 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 42 84 0 ENST00000377966.3:c.2254C>T p.Pro752Ser p.P752S ENST00000377966 NM_021111.2 752 Ccc/Tcc 0 +REEP1 UCSF GRCh37 2 86444230 86444230 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 44 95 0 ENST00000165698.5:c.599C>T p.Thr200Ile p.T200I ENST00000165698 NM_022912.2 200 aCc/aTc 0 +REEP5 UCSF GRCh37 5 112257851 112257851 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 13 38 0 ENST00000379638.4:c.37C>T p.Leu13= p.L13= ENST00000379638 NM_005669.4 13 Ctg/Ttg 0 +RELB UCSF GRCh37 19 45537734 45537734 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 18 63 0 ENST00000221452.8:c.1302G>A p.Arg434= p.R434= ENST00000221452 NM_006509.3 434 cgG/cgA 0 +REM2 UCSF GRCh37 14 23354170 23354170 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 51 87 0 ENST00000267396.4:c.391G>A p.Ala131Thr p.A131T ENST00000267396 NM_173527.2 131 Gca/Aca 0 +REV3L UCSF GRCh37 6 111694354 111694354 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 154 121 213 0 ENST00000358835.3:c.5204G>A p.Ser1735Asn p.S1735N ENST00000358835 1735 aGc/aAc 0 +REV3L UCSF GRCh37 6 111678216 111678216 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 83 208 0 ENST00000358835.3:c.7184+1G>A p.X2395_splice ENST00000358835 0 +RFPL2 UCSF GRCh37 22 32588955 32588955 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 99 212 0 ENST00000248983.4:c.220A>T p.Ile74Phe p.I74F ENST00000248983 NM_001159545.1 74 Atc/Ttc 0 +RGNEF UCSF GRCh37 5 73072480 73072480 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 233 141 367 0 ENST00000426542.2:c.799C>T p.Leu267Phe p.L267F ENST00000426542 267 Ctc/Ttc 0 +RGS10 UCSF GRCh37 10 121285617 121285617 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P18_Rec Untested WXS Illumina HiSeq 30 0 ENST00000369101.3:c.158del p.Lys53ArgfsTer12 p.K53Rfs*12 ENST00000369101 53 aAg/ag 0 +RGS20 UCSF GRCh37 8 54791981 54791981 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 38 94 0 ENST00000297313.3:c.329C>T p.Ala110Val p.A110V ENST00000297313 NM_170587.2 110 gCc/gTc 0 +RGS22 UCSF GRCh37 8 101076176 101076176 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 153 105 244 0 ENST00000360863.6:c.820G>A p.Glu274Lys p.E274K ENST00000360863 NM_015668.3 274 Gaa/Aaa 0 +RHBDF2 UCSF GRCh37 17 74469187 74469187 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 35 61 0 ENST00000313080.4:c.1897G>A p.Val633Met p.V633M ENST00000313080 NM_024599.5 633 Gtg/Atg 0 +RHCE UCSF GRCh37 1 25715505 25715505 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 51 140 0 ENST00000294413.7:c.901G>A p.Ala301Thr p.A301T ENST00000294413 NM_020485.4 301 Gct/Act 0 +RHOBTB1 UCSF GRCh37 10 62670645 62670645 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 43 112 0 ENST00000337910.5:c.296G>A p.Arg99Lys p.R99K ENST00000337910 NM_001242359.1 99 aGg/aAg 0 +RHOBTB2 UCSF GRCh37 8 22868171 22868171 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 101 198 0 ENST00000251822.6:c.1741C>T p.Leu581Phe p.L581F ENST00000251822 NM_015178.2 581 Ctc/Ttc 0 +RHPN1 UCSF GRCh37 8 144462236 144462236 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 15 28 0 ENST00000289013.6:c.1107G>A p.Ala369= p.A369= ENST00000289013 NM_052924.2 369 gcG/gcA 0 +RIMS1 UCSF GRCh37 6 72892596 72892596 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 11 14 0 ENST00000521978.1:c.1422C>T p.Ser474= p.S474= ENST00000521978 NM_014989.5 474 agC/agT 0 +RIN2 UCSF GRCh37 20 19970700 19970700 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 46 112 0 ENST00000255006.6:c.1960G>A p.Gly654Arg p.G654R ENST00000255006 NM_018993.3 654 Ggg/Agg 0 +RIN2 UCSF GRCh37 20 19945668 19945668 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 173 130 267 0 ENST00000255006.6:c.683G>A p.Arg228Lys p.R228K ENST00000255006 NM_018993.3 228 aGg/aAg 0 +RING1 UCSF GRCh37 6 33179242 33179242 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 8 24 0 ENST00000374656.4:c.763C>T p.Pro255Ser p.P255S ENST00000374656 NM_002931.3 255 Ccc/Tcc 0 +RIPK4 UCSF GRCh37 21 43161833 43161833 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 47 118 0 ENST00000352483.2:c.1664C>T p.Ala555Val p.A555V ENST00000352483 555 gCc/gTc 0 +RIPK4 UCSF GRCh37 21 43171318 43171318 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 68 129 0 ENST00000352483.2:c.562C>T p.Leu188Phe p.L188F ENST00000352483 188 Ctc/Ttc 0 +RLF UCSF GRCh37 1 40688383 40688383 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 69 180 0 ENST00000372771.4:c.947+1G>A p.X316_splice ENST00000372771 NM_012421.3 0 +RLN3 UCSF GRCh37 19 14141712 14141712 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 43 157 0 ENST00000431365.2:c.381C>T p.Ser127= p.S127= ENST00000431365 NM_080864.2 127 agC/agT 0 +RLTPR UCSF GRCh37 16 67690536 67690536 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 29 64 0 ENST00000334583.6:c.4024C>T p.Pro1342Ser p.P1342S ENST00000334583 NM_001013838.1 1342 Ccc/Tcc 0 +RNF123 UCSF GRCh37 3 49750002 49750002 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 56 121 0 ENST00000327697.6:c.2587C>T p.Pro863Ser p.P863S ENST00000327697 NM_022064.3 863 Ccc/Tcc 0 +RNF168 UCSF GRCh37 3 196229968 196229968 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 57 129 0 ENST00000318037.3:c.77C>T p.Pro26Leu p.P26L ENST00000318037 NM_152617.3 26 cCc/cTc 0 +RNF208 UCSF GRCh37 9 140114906 140114906 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 8 12 0 ENST00000391553.1:c.759C>T p.Asn253= p.N253= ENST00000391553 NM_031297.4 253 aaC/aaT 0 +RNF25 UCSF GRCh37 2 219528704 219528704 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 72 150 0 ENST00000295704.2:c.1356C>T p.Gly452= p.G452= ENST00000295704 NM_022453.2 452 ggC/ggT 0 +RNF32 UCSF GRCh37 7 156437244 156437244 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 63 101 0 ENST00000317955.5:c.67G>A p.Asp23Asn p.D23N ENST00000317955 NM_030936.3 23 Gat/Aat 0 +RP1L1 UCSF GRCh37 8 10468205 10468205 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 69 174 0 ENST00000382483.3:c.3403C>T p.Pro1135Ser p.P1135S ENST00000382483 NM_178857.5 1135 Cct/Tct 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 51 117 0 ENST00000272274.4:c.398C>T p.Ala133Val p.A133V ENST00000272274 133 gCt/gTt 0 +RPL22L1 UCSF GRCh37 3 170584270 170584270 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 61 141 0 ENST00000295830.8:c.268C>T p.Leu90Phe p.L90F ENST00000295830 NM_001099645.1 90 Ctt/Ttt 0 +RPL5 UCSF GRCh37 1 93300406 93300406 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 200 133 278 0 ENST00000370321.3:c.260G>A p.Gly87Asp p.G87D ENST00000370321 NM_000969.3 87 gGt/gAt 0 +RPL5 UCSF GRCh37 1 93301773 93301773 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 160 99 254 0 ENST00000370321.3:c.351G>A p.Lys117= p.K117= ENST00000370321 NM_000969.3 117 aaG/aaA 0 +RPL8 UCSF GRCh37 8 146017481 146017481 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 11 37 0 ENST00000262584.3:c.34G>A p.Ala12Thr p.A12T ENST00000262584 NM_000973.3 12 Gcc/Acc 0 +RPLP0 UCSF GRCh37 12 120637204 120637204 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 62 142 0 ENST00000228306.4:c.139C>T p.Leu47Phe p.L47F ENST00000228306 NM_053275.3 47 Ctt/Ttt 0 +RPP38 UCSF GRCh37 10 15145394 15145394 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 238 92 190 0 ENST00000378197.4:c.81C>T p.Asn27= p.N27= ENST00000378197 NM_183005.4 27 aaC/aaT 0 +RPS10 UCSF GRCh37 6 34389575 34389575 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 143 125 213 0 ENST00000326199.8:c.332G>A p.Gly111Asp p.G111D ENST00000326199 NM_001014.4 111 gGt/gAt 0 +RPS6KA4 UCSF GRCh37 11 64129475 64129475 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 34 91 0 ENST00000334205.4:c.906+1G>A p.X302_splice ENST00000334205 NM_003942.2 0 +RRP15 UCSF GRCh37 1 218480844 218480844 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 72 137 0 ENST00000366932.3:c.575G>A p.Gly192Glu p.G192E ENST00000366932 NM_016052.3 192 gGa/gAa 0 +RSAD1 UCSF GRCh37 17 48559649 48559649 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 43 100 0 ENST00000258955.2:c.672C>T p.Ser224= p.S224= ENST00000258955 NM_018346.1 224 tcC/tcT 0 +RSPH10B UCSF GRCh37 7 5967960 5967960 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 583 156 606 0 ENST00000337579.3:c.2299G>A p.Val767Ile p.V767I ENST00000337579 767 Gtc/Atc 0 +RSU1 UCSF GRCh37 10 16794618 16794618 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 293 169 279 0 ENST00000345264.5:c.518C>T p.Pro173Leu p.P173L ENST00000345264 NM_012425.3 173 cCt/cTt 0 +RTCD1 UCSF GRCh37 1 100757039 100757039 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 158 114 257 0 ENST00000370128.4:c.1080G>A p.Gly360= p.G360= ENST00000370128 NM_003729.3 360 ggG/ggA 0 +RTL1 UCSF GRCh37 14 101348097 101348097 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 80 187 0 ENST00000534062.1:c.3029C>T p.Ala1010Val p.A1010V ENST00000534062 NM_001134888.2 1010 gCc/gTc 0 +RUFY2 UCSF GRCh37 10 70115139 70115139 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 21 108 0 ENST00000388768.2:c.1675G>A p.Asp559Asn p.D559N ENST00000388768 NM_017987.4 559 Gac/Aac 0 +RUSC1 UCSF GRCh37 1 155296523 155296523 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 49 126 0 ENST00000368352.5:c.2014C>T p.Pro672Ser p.P672S ENST00000368352 NM_001105203.1 672 Ccc/Tcc 0 +RYR1 UCSF GRCh37 19 38964107 38964107 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 22 72 0 ENST00000359596.3:c.3856C>T p.Leu1286Phe p.L1286F ENST00000359596 1286 Ctt/Ttt 0 +RYR2 UCSF GRCh37 1 237811891 237811891 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 67 136 0 ENST00000366574.2:c.7490G>A p.Arg2497Gln p.R2497Q ENST00000366574 NM_001035.2 2497 cGg/cAg 0 +RYR3 UCSF GRCh37 15 34023823 34023823 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 186 124 280 0 ENST00000389232.4:c.7352G>A p.Arg2451Lys p.R2451K ENST00000389232 NM_001036.3 2451 aGg/aAg 0 +RYR3 UCSF GRCh37 15 33936690 33936690 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 85 221 0 ENST00000389232.4:c.3735C>T p.Val1245= p.V1245= ENST00000389232 NM_001036.3 1245 gtC/gtT 0 +S100A7 UCSF GRCh37 1 153430419 153430419 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 195 30 176 1 ENST00000368722.1:c.169G>A p.Asp57Asn p.D57N ENST00000368722 57 Gat/Aat 0 +S100A7 UCSF GRCh37 1 153430418 153430418 + missense_variant Missense_Mutation SNP T T G NOVEL P18_Rec Untested WXS Illumina HiSeq 196 33 178 0 ENST00000368722.1:c.170A>C p.Asp57Ala p.D57A ENST00000368722 57 gAt/gCt 0 +S100A7 UCSF GRCh37 1 153430338 153430338 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.003,snp132_rs56232841 P18_Rec Untested WXS Illumina HiSeq 158 52 146 0 ENST00000368722.1:c.250A>G p.Thr84Ala p.T84A ENST00000368722 84 Aca/Gca 0 +S100A7 UCSF GRCh37 1 153430309 153430309 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 139 38 125 0 ENST00000368722.1:c.279A>G p.Ala93= p.A93= ENST00000368722 93 gcA/gcG 0 +S1PR3 UCSF GRCh37 9 91616518 91616518 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 63 138 0 ENST00000358157.2:c.403G>A p.Glu135Lys p.E135K ENST00000358157 NM_005226.3 135 Gag/Aag 0 +S1PR5 UCSF GRCh37 19 10625409 10625409 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 12 29 0 ENST00000333430.4:c.279C>T p.Ile93= p.I93= ENST00000333430 NM_030760.4 93 atC/atT 0 +SAFB UCSF GRCh37 19 5653197 5653197 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 55 115 0 ENST00000292123.5:c.1365C>T p.Ser455= p.S455= ENST00000292123 NM_002967.3 455 tcC/tcT 0 +SALL3 UCSF GRCh37 18 76753259 76753259 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 29 50 1 ENST00000537592.2:c.1268G>A p.Arg423His p.R423H ENST00000537592 NM_171999.3 423 cGc/cAc 0 +SAMD11 UCSF GRCh37 1 865678 865678 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 5 20 0 ENST00000342066.3:c.216G>A p.Lys72= p.K72= ENST00000342066 NM_152486.2 72 aaG/aaA 0 +SAMD15 UCSF GRCh37 14 77844599 77844599 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 143 129 269 0 ENST00000216471.4:c.838C>T p.Pro280Ser p.P280S ENST00000216471 NM_001010860.1 280 Cct/Tct 0 +SAMD9L UCSF GRCh37 7 92763754 92763754 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 143 99 195 0 ENST00000318238.4:c.1531C>T p.Pro511Ser p.P511S ENST00000318238 NM_152703.2 511 Cct/Tct 0 +SARS2 UCSF GRCh37 19 39421155 39421155 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 34 91 0 ENST00000221431.6:c.222G>A p.Leu74= p.L74= ENST00000221431 NM_017827.3 74 ctG/ctA 0 +SART1 UCSF GRCh37 11 65743941 65743941 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 27 17 54 0 ENST00000312397.5:c.1648G>A p.Ala550Thr p.A550T ENST00000312397 NM_005146.4 550 Gcc/Acc 0 +SBF1 UCSF GRCh37 22 50893824 50893824 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 23 58 0 ENST00000380817.3:c.4383G>A p.Val1461= p.V1461= ENST00000380817 NM_002972.2 1461 gtG/gtA 0 +SBK2 UCSF GRCh37 19 56041272 56041272 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 6 15 0 ENST00000344158.3:c.875C>T p.Pro292Leu p.P292L ENST00000344158 292 cCc/cTc 0 +SCAI UCSF GRCh37 9 127783049 127783049 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 76 164 0 ENST00000336505.6:c.513-1G>A p.X171_splice ENST00000336505 NM_001144877.2 0 +SCAPER UCSF GRCh37 15 77067433 77067433 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 82 189 0 ENST00000324767.7:c.798G>A p.Glu266= p.E266= ENST00000324767 NM_020843.2 266 gaG/gaA 0 +SCLY UCSF GRCh37 2 238973011 238973011 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 41 119 0 ENST00000254663.6:c.127G>A p.Asp43Asn p.D43N ENST00000254663 NM_016510.5 43 Gac/Aac 0 +SCN3A UCSF GRCh37 2 166003442 166003442 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 104 243 0 ENST00000360093.3:c.1478C>T p.Ser493Phe p.S493F ENST00000360093 NM_001081677.1 493 tCc/tTc 0 +SCNN1D UCSF GRCh37 1 1223152 1223152 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 6 13 0 ENST00000338555.2:c.1007C>T p.Pro336Leu p.P336L ENST00000338555 336 cCc/cTc 0 +SCO2 UCSF GRCh37 22 50962564 50962564 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 43 81 0 ENST00000252785.3:c.277G>A p.Ala93Thr p.A93T ENST00000252785 NM_001169111.1 93 Gcc/Acc 0 +SCOC UCSF GRCh37 4 141300319 141300319 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 199 142 313 0 ENST00000608372.1:c.226C>T p.Pro76Ser p.P76S ENST00000608372 76 Ccc/Tcc 0 +SCRIB UCSF GRCh37 8 144873903 144873903 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 48 0 ENST00000320476.3:c.4695+143C>T *1565* ENST00000320476 NM_015356.4 0 +SCYL1 UCSF GRCh37 11 65293669 65293669 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 33 71 0 ENST00000270176.5:c.450C>T p.Asp150= p.D150= ENST00000270176 NM_020680.3 150 gaC/gaT 0 +SDC4 UCSF GRCh37 20 43964433 43964433 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 54 122 0 ENST00000372733.3:c.188C>T p.Ser63Phe p.S63F ENST00000372733 NM_002999.3 63 tCt/tTt 0 +SDCCAG3 UCSF GRCh37 9 139301615 139301615 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 22 78 0 ENST00000357365.3:c.801G>A p.Leu267= p.L267= ENST00000357365 NM_001039707.1 267 ctG/ctA 0 +SDK1 UCSF GRCh37 7 4119212 4119212 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 68 168 0 ENST00000404826.2:c.3320G>A p.Gly1107Glu p.G1107E ENST00000404826 NM_152744.3 1107 gGg/gAg 0 +SEBOX UCSF GRCh37 17 26691913 26691913 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 30 58 0 ENST00000555059.2:c.394G>A p.Gly132Arg p.G132R ENST00000555059 132 Gga/Aga 0 +SEC11A UCSF GRCh37 15 85223946 85223946 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 158 111 232 0 ENST00000268220.7:c.429G>A p.Arg143= p.R143= ENST00000268220 NM_014300.3 143 agG/agA 0 +SEC13 UCSF GRCh37 3 10346745 10346745 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 40 87 0 ENST00000350697.3:c.680C>T p.Pro227Leu p.P227L ENST00000350697 NM_183352.2 227 cCc/cTc 0 +SEC14L6 UCSF GRCh37 22 30921822 30921822 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 40 111 0 ENST00000402034.2:c.762C>T p.Cys254= p.C254= ENST00000402034 NM_001193336.2 254 tgC/tgT 0 +SEC16A UCSF GRCh37 9 139361486 139361486 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 86 178 0 ENST00000313050.7:c.3852C>T p.Pro1284= p.P1284= ENST00000313050 NM_014866.1 1284 ccC/ccT 0 +SEC22A UCSF GRCh37 3 122928095 122928095 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 79 162 0 ENST00000309934.4:c.31C>T p.Arg11Cys p.R11C ENST00000309934 NM_012430.4 11 Cgt/Tgt 0 +SEC24B UCSF GRCh37 4 110394304 110394304 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 83 171 0 ENST00000265175.5:c.1022C>T p.Thr341Ile p.T341I ENST00000265175 NM_006323.2 341 aCc/aTc 0 +SEC24D UCSF GRCh37 4 119718875 119718875 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 69 158 0 ENST00000280551.6:c.1004C>T p.Ala335Val p.A335V ENST00000280551 335 gCt/gTt 0 +SEC31A UCSF GRCh37 4 83799897 83799897 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 71 150 0 ENST00000355196.2:c.388G>A p.Val130Met p.V130M ENST00000355196 130 Gtg/Atg 0 +SEC31B UCSF GRCh37 10 102258480 102258480 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 75 146 0 ENST00000370345.3:c.1666G>A p.Glu556Lys p.E556K ENST00000370345 NM_015490.3 556 Gag/Aag 0 +SEC61A1 UCSF GRCh37 3 127785931 127785931 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 142 94 194 0 ENST00000243253.3:c.912C>T p.Ile304= p.I304= ENST00000243253 NM_013336.3 304 atC/atT 0 +SELE UCSF GRCh37 1 169698710 169698710 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 91 175 0 ENST00000333360.7:c.820G>A p.Glu274Lys p.E274K ENST00000333360 NM_000450.2 274 Gaa/Aaa 0 +SELV UCSF GRCh37 19 40009788 40009788 + stop_retained_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 35 74 0 ENST00000335426.4:c.1041G>A p.Ter347= p.*347= ENST00000335426 NM_182704.1 347 taG/taA 0 +SEMA3E UCSF GRCh37 7 83047781 83047781 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 36 61 0 ENST00000307792.3:c.475G>A p.Glu159Lys p.E159K ENST00000307792 NM_012431.2 159 Gaa/Aaa 0 +SEMA4A UCSF GRCh37 1 156128558 156128558 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 156 99 220 0 ENST00000355014.2:c.511G>A p.Glu171Lys p.E171K ENST00000355014 NM_001193301.1 171 Gag/Aag 0 +SEMA4B UCSF GRCh37 15 90764230 90764230 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 47 98 0 ENST00000411539.2:c.500C>T p.Thr167Ile p.T167I ENST00000411539 NM_198925.2 167 aCc/aTc 0 +SEMA4C UCSF GRCh37 2 97529843 97529843 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 24 60 0 ENST00000305476.5:c.1150C>T p.Leu384= p.L384= ENST00000305476 NM_017789.4 384 Ctg/Ttg 0 +SEMA4D UCSF GRCh37 9 91978436 91978436 + downstream_gene_variant 3'Flank SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 26 60 0 ENST00000375807 NM_024077.3 0 +SEMA5A UCSF GRCh37 5 9122932 9122932 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 47 117 0 ENST00000382496.5:c.1617G>A p.Val539= p.V539= ENST00000382496 NM_003966.2 539 gtG/gtA 0 +SEMA6C UCSF GRCh37 1 151105838 151105838 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 8 19 0 ENST00000341697.3:c.1915G>A p.Asp639Asn p.D639N ENST00000341697 639 Gac/Aac 0 +SEMA6D UCSF GRCh37 15 48056446 48056446 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 83 151 0 ENST00000316364.5:c.1041G>A p.Gln347= p.Q347= ENST00000316364 NM_153618.1 347 caG/caA 0 +SEMG2 UCSF GRCh37 20 43852008 43852008 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 58 138 0 ENST00000372769.3:c.1735C>T p.Pro579Ser p.P579S ENST00000372769 NM_003008.2 579 Cca/Tca 0 +SEPN1 UCSF GRCh37 1 26131720 26131720 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 59 146 0 ENST00000361547.2:c.491C>T p.Pro164Leu p.P164L ENST00000361547 NM_020451.2 164 cCt/cTt 0 +SEPT1 UCSF GRCh37 16 30392662 30392662 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 74 94 0 ENST00000321367.3:c.579G>A p.Arg193= p.R193= ENST00000321367 NM_052838.4 193 cgG/cgA 0 +SEPT3 UCSF GRCh37 22 42388723 42388723 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 13 45 0 ENST00000396426.3:c.821G>A p.Gly274Asp p.G274D ENST00000396426 NM_145733.2 274 gGc/gAc 0 +SEPT3 UCSF GRCh37 22 42382070 42382070 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 29 57 0 ENST00000396426.3:c.285G>A p.Arg95= p.R95= ENST00000396426 NM_145733.2 95 cgG/cgA 0 +SERAC1 UCSF GRCh37 6 158576362 158576362 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 39 90 0 ENST00000367104.3:c.113G>A p.Gly38Glu p.G38E ENST00000367104 NM_032861.3 38 gGa/gAa 0 +SERPINB12 UCSF GRCh37 18 61228327 61228327 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 111 262 0 ENST00000269491.1:c.394G>A p.Asp132Asn p.D132N ENST00000269491 NM_080474.1 132 Gat/Aat 0 +SERPINB3 UCSF GRCh37 18 61323037 61323037 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 144 104 202 0 ENST00000283752.5:c.1027G>A p.Ala343Thr p.A343T ENST00000283752 NM_006919.2 343 Gct/Act 0 +SERPINF1 UCSF GRCh37 17 1675304 1675304 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 36 107 0 ENST00000254722.4:c.578C>T p.Ala193Val p.A193V ENST00000254722 NM_002615.5 193 gCc/gTc 0 +SETBP1 UCSF GRCh37 18 42531407 42531407 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 61 107 0 ENST00000282030.5:c.2102G>A p.Gly701Glu p.G701E ENST00000282030 NM_015559.2 701 gGg/gAg 0 +SETD1A UCSF GRCh37 16 30977303 30977303 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 54 143 0 ENST00000262519.8:c.2101G>A p.Ala701Thr p.A701T ENST00000262519 NM_014712.1 701 Gcc/Acc 0 +SETMAR UCSF GRCh37 3 4355176 4355176 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 352 86 190 0 ENST00000358065.4:c.751G>A p.Asp251Asn p.D251N ENST00000358065 NM_006515.3 251 Gat/Aat 0 +SEZ6 UCSF GRCh37 17 27286898 27286898 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 24 54 0 ENST00000317338.12:c.1589G>A p.Gly530Asp p.G530D ENST00000317338 530 gGc/gAc 0 +SF3B2 UCSF GRCh37 11 65824827 65824827 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 77 160 0 ENST00000322535.6:c.758C>T p.Pro253Leu p.P253L ENST00000322535 NM_006842.2 253 cCt/cTt 0 +SFSWAP UCSF GRCh37 12 132237854 132237854 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 50 89 0 ENST00000261674.4:c.1268C>T p.Pro423Leu p.P423L ENST00000261674 NM_004592.3 423 cCc/cTc 0 +SFTPA1 UCSF GRCh37 10 81371624 81371624 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 85 173 0 ENST00000398636.3:c.43G>A p.Ala15Thr p.A15T ENST00000398636 NM_005411.4 15 Gcc/Acc 0 +SFTPA2 UCSF GRCh37 10 81319071 81319071 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 48 134 0 ENST00000372325.2:c.169C>T p.Pro57Ser p.P57S ENST00000372325 NM_001098668.2 57 Cca/Tca 0 +SGIP1 UCSF GRCh37 1 67195022 67195022 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P18_Rec Untested WXS Illumina HiSeq 113 81 185 0 ENST00000371037.4:c.1818G>A p.Pro606= p.P606= ENST00000371037 NM_032291.2 606 ccG/ccA 0 +SGK223 UCSF GRCh37 8 8185635 8185635 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 158 124 201 0 ENST00000520004.1:c.2657G>A p.Gly886Asp p.G886D ENST00000520004 886 gGc/gAc 0 +SGK223 UCSF GRCh37 8 8185896 8185896 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 39 87 0 ENST00000520004.1:c.2396C>T p.Thr799Ile p.T799I ENST00000520004 799 aCt/aTt 0 +SGK223 UCSF GRCh37 8 8176294 8176294 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 9 35 0 ENST00000520004.1:c.3591G>A p.Pro1197= p.P1197= ENST00000520004 1197 ccG/ccA 0 +SGMS1 UCSF GRCh37 10 52067029 52067029 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 48 94 0 ENST00000361781.2:c.1115G>A p.Arg372Lys p.R372K ENST00000361781 NM_147156.3 372 aGg/aAg 0 +SGPL1 UCSF GRCh37 10 72619236 72619236 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 44 107 0 ENST00000373202.3:c.595G>A p.Gly199Arg p.G199R ENST00000373202 NM_003901.3 199 Gga/Aga 0 +SGPP2 UCSF GRCh37 2 223423585 223423585 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 72 154 0 ENST00000321276.7:c.1168C>T p.Pro390Ser p.P390S ENST00000321276 NM_152386.2 390 Ccg/Tcg 0 +SH3BP4 UCSF GRCh37 2 235949844 235949844 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 102 61 153 0 ENST00000344528.4:c.431G>A p.Gly144Glu p.G144E ENST00000344528 144 gGa/gAa 0 +SH3BP4 UCSF GRCh37 2 235949878 235949878 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 66 165 0 ENST00000344528.4:c.465G>A p.Met155Ile p.M155I ENST00000344528 155 atG/atA 0 +SH3RF2 UCSF GRCh37 5 145442142 145442142 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 53 119 0 ENST00000359120.4:c.2068G>A p.Ala690Thr p.A690T ENST00000359120 NM_152550.3 690 Gcc/Acc 0 +SHANK1 UCSF GRCh37 19 51172385 51172385 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 6 8 16 0 ENST00000293441.1:c.2832C>T p.Arg944= p.R944= ENST00000293441 NM_016148.2 944 cgC/cgT 0 +SHANK2 UCSF GRCh37 11 70319358 70319358 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 48 126 0 ENST00000423696.2:c.4029G>A p.Leu1343= p.L1343= ENST00000423696 1343 ctG/ctA 0 +SHC1 UCSF GRCh37 1 154942558 154942558 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 61 133 0 ENST00000368445.5:c.445C>T p.Leu149= p.L149= ENST00000368445 NM_183001.4 149 Ctg/Ttg 0 +SHC2 UCSF GRCh37 19 422180 422180 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 26 45 0 ENST00000264554.6:c.1586C>T p.Pro529Leu p.P529L ENST00000264554 NM_012435.2 529 cCc/cTc 0 +SHD UCSF GRCh37 19 4288240 4288240 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 25 97 0 ENST00000543264.2:c.717G>A p.Pro239= p.P239= ENST00000543264 NM_020209.3 239 ccG/ccA 0 +SHMT1 UCSF GRCh37 17 18250882 18250882 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 80 190 0 ENST00000316694.3:c.447G>A p.Leu149= p.L149= ENST00000316694 NM_004169.3 149 ctG/ctA 0 +SHROOM3 UCSF GRCh37 4 77700237 77700237 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 76 168 0 ENST00000296043.6:c.5898C>T p.Ala1966= p.A1966= ENST00000296043 NM_020859.3 1966 gcC/gcT 0 +SI UCSF GRCh37 3 164750338 164750338 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 68 180 0 ENST00000264382.3:c.2708C>T p.Ser903Phe p.S903F ENST00000264382 NM_001041.3 903 tCc/tTc 0 +SIGLEC1 UCSF GRCh37 20 3677521 3677521 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 39 22 50 0 ENST00000344754.4:c.2395C>T p.Pro799Ser p.P799S ENST00000344754 NM_023068.3 799 Cca/Tca 0 +SIK1 UCSF GRCh37 21 44839319 44839319 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 18 46 0 ENST00000270162.6:c.1159G>A p.Ala387Thr p.A387T ENST00000270162 NM_173354.3 387 Gcc/Acc 0 +SIK2 UCSF GRCh37 11 111591297 111591297 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 76 157 0 ENST00000304987.3:c.1591G>A p.Asp531Asn p.D531N ENST00000304987 NM_015191.1 531 Gac/Aac 0 +SIL1 UCSF GRCh37 5 138282962 138282962 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 23 79 0 ENST00000265195.5:c.1230C>T p.Asp410= p.D410= ENST00000265195 NM_001037633.1 410 gaC/gaT 0 +SIN3A UCSF GRCh37 15 75715130 75715130 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 31 141 0 ENST00000360439.4:c.224G>A p.Gly75Glu p.G75E ENST00000360439 NM_001145357.1 75 gGg/gAg 0 +SIPA1L1 UCSF GRCh37 14 72196876 72196876 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 60 175 1 ENST00000555818.1:c.4782G>A p.Arg1594= p.R1594= ENST00000555818 NM_015556.1 1594 agG/agA 0 +SIPA1L3 UCSF GRCh37 19 38597280 38597280 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 58 116 0 ENST00000222345.6:c.2133G>A p.Gln711= p.Q711= ENST00000222345 NM_015073.1 711 caG/caA 0 +SKAP2 UCSF GRCh37 7 26778483 26778483 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 81 163 0 ENST00000345317.2:c.400G>A p.Gly134Arg p.G134R ENST00000345317 NM_003930.3 134 Gga/Aga 0 +SKI UCSF GRCh37 1 2235395 2235395 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 18 36 0 ENST00000378536.4:c.1328C>T p.Pro443Leu p.P443L ENST00000378536 NM_003036.3 443 cCc/cTc 0 +SKIV2L UCSF GRCh37 6 31936246 31936246 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 50 92 0 ENST00000375394.2:c.3000C>T p.Leu1000= p.L1000= ENST00000375394 NM_006929.4 1000 ctC/ctT 0 +SKIV2L UCSF GRCh37 6 31928217 31928217 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 173 135 282 0 ENST00000375394.2:c.363G>A p.Leu121= p.L121= ENST00000375394 NM_006929.4 121 ctG/ctA 0 +SKIV2L2 UCSF GRCh37 5 54640934 54640934 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 32 84 0 ENST00000230640.5:c.1018G>A p.Glu340Lys p.E340K ENST00000230640 NM_015360.4 340 Gaa/Aaa 0 +SLAMF1 UCSF GRCh37 1 160607134 160607134 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 88 193 0 ENST00000302035.6:c.262C>T p.Pro88Ser p.P88S ENST00000302035 NM_003037.2 88 Cct/Tct 0 +SLAMF6 UCSF GRCh37 1 160465922 160465922 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 99 178 0 ENST00000368057.3:c.311C>T p.Thr104Ile p.T104I ENST00000368057 104 aCa/aTa 0 +SLC12A3 UCSF GRCh37 16 56913080 56913080 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 44 10 54 1 ENST00000563236.1:c.1276A>G p.Asn426Asp p.N426D ENST00000563236 426 Aac/Gac 0 +SLC14A2 UCSF GRCh37 18 43212405 43212405 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 89 212 0 ENST00000255226.6:c.612G>T p.Trp204Cys p.W204C ENST00000255226 NM_007163.3 204 tgG/tgT 0 +SLC15A1 UCSF GRCh37 13 99361913 99361913 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 61 146 0 ENST00000376503.5:c.980C>T p.Thr327Ile p.T327I ENST00000376503 NM_005073.3 327 aCc/aTc 0 +SLC15A2 UCSF GRCh37 3 121659250 121659250 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 52 113 0 ENST00000489711.1:c.1928C>T p.Ser643Phe p.S643F ENST00000489711 NM_021082.3 643 tCt/tTt 0 +SLC15A3 UCSF GRCh37 11 60706981 60706981 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 21 63 0 ENST00000227880.3:c.1406G>A p.Gly469Glu p.G469E ENST00000227880 NM_016582.2 469 gGg/gAg 0 +SLC16A1 UCSF GRCh37 1 113464699 113464699 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 73 149 0 ENST00000369626.3:c.274G>A p.Gly92Ser p.G92S ENST00000369626 NM_003051.3 92 Ggt/Agt 0 +SLC17A3 UCSF GRCh37 6 25850111 25850111 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 92 201 0 ENST00000360657.3:c.959C>T p.Ala320Val p.A320V ENST00000360657 320 gCc/gTc 0 +SLC17A9 UCSF GRCh37 20 61588814 61588814 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 36 85 0 ENST00000370351.4:c.279C>T p.Ile93= p.I93= ENST00000370351 NM_022082.3 93 atC/atT 0 +SLC18A3 UCSF GRCh37 10 50819055 50819055 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 35 81 0 ENST00000374115.3:c.269C>T p.Ala90Val p.A90V ENST00000374115 NM_003055.2 90 gCc/gTc 0 +SLC19A3 UCSF GRCh37 2 228564098 228564098 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 140 120 262 0 ENST00000258403.3:c.333C>T p.Phe111= p.F111= ENST00000258403 NM_025243.3 111 ttC/ttT 0 +SLC1A7 UCSF GRCh37 1 53569205 53569205 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 14 6 24 0 ENST00000371494.4:c.510C>T p.Pro170= p.P170= ENST00000371494 NM_006671.4 170 ccC/ccT 0 +SLC1A7 UCSF GRCh37 1 53558287 53558287 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 43 92 0 ENST00000371494.4:c.970C>T p.Pro324Ser p.P324S ENST00000371494 NM_006671.4 324 Ccc/Tcc 0 +SLC22A23 UCSF GRCh37 6 3324091 3324091 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 18 58 0 ENST00000406686.3:c.1059C>T p.Phe353= p.F353= ENST00000406686 NM_015482.1 353 ttC/ttT 0 +SLC22A24 UCSF GRCh37 11 62910949 62910949 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 59 186 0 ENST00000326192.5:c.303G>A p.Leu101= p.L101= ENST00000326192 101 ctG/ctA 0 +SLC22A9 UCSF GRCh37 11 63174117 63174117 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 78 120 0 ENST00000279178.3:c.1222G>A p.Ala408Thr p.A408T ENST00000279178 NM_080866.2 408 Gca/Aca 0 +SLC22A9 UCSF GRCh37 11 63176153 63176153 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 53 109 0 ENST00000279178.3:c.1403G>A p.Arg468Lys p.R468K ENST00000279178 NM_080866.2 468 aGa/aAa 0 +SLC22A9 UCSF GRCh37 11 63174096 63174096 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec Untested WXS Illumina HiSeq 104 89 141 0 ENST00000279178.3:c.1201C>G p.Leu401Val p.L401V ENST00000279178 NM_080866.2 401 Ctg/Gtg 0 +SLC23A2 UCSF GRCh37 20 4842731 4842731 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 50 104 0 ENST00000338244.1:c.1487G>A p.Gly496Glu p.G496E ENST00000338244 NM_005116.5 496 gGa/gAa 0 +SLC24A1 UCSF GRCh37 15 65917613 65917613 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 66 174 0 ENST00000261892.6:c.1195C>T p.Pro399Ser p.P399S ENST00000261892 NM_004727.2 399 Cca/Tca 0 +SLC24A1 UCSF GRCh37 15 65943185 65943185 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 79 201 0 ENST00000261892.6:c.2698G>A p.Asp900Asn p.D900N ENST00000261892 NM_004727.2 900 Gac/Aac 0 +SLC24A3 UCSF GRCh37 20 19261715 19261715 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 45 130 0 ENST00000328041.6:c.255G>A p.Lys85= p.K85= ENST00000328041 NM_020689.3 85 aaG/aaA 0 +SLC24A6 UCSF GRCh37 12 113744348 113744348 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 39 67 0 ENST00000202831.3:c.1444G>A p.Gly482Ser p.G482S ENST00000202831 NM_024959.2 482 Ggc/Agc 0 +SLC24A6 UCSF GRCh37 12 113753213 113753213 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 6 9 20 0 ENST00000202831.3:c.1062G>A p.Trp354Ter p.W354* ENST00000202831 NM_024959.2 354 tgG/tgA 0 +SLC25A13 UCSF GRCh37 7 95799390 95799390 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 113 237 0 ENST00000265631.5:c.1278C>T p.Val426= p.V426= ENST00000265631 426 gtC/gtT 0 +SLC25A32 UCSF GRCh37 8 104417054 104417054 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 39 98 0 ENST00000297578.4:c.341G>A p.Arg114Lys p.R114K ENST00000297578 NM_030780.4 114 aGa/aAa 0 +SLC26A2 UCSF GRCh37 5 149360728 149360728 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 174 152 280 0 ENST00000286298.4:c.1572G>A p.Leu524= p.L524= ENST00000286298 NM_000112.3 524 ctG/ctA 0 +SLC26A7 UCSF GRCh37 8 92307932 92307932 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 57 118 0 ENST00000276609.3:c.477+1G>A p.X159_splice ENST00000276609 NM_052832.2 0 +SLC27A4 UCSF GRCh37 9 131107677 131107677 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 31 58 0 ENST00000300456.4:c.405C>T p.Asn135= p.N135= ENST00000300456 NM_005094.3 135 aaC/aaT 0 +SLC29A1 UCSF GRCh37 6 44199835 44199835 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 51 92 0 ENST00000371708.1:c.965G>A p.Ser322Asn p.S322N ENST00000371708 322 aGc/aAc 0 +SLC2A1 UCSF GRCh37 1 43395384 43395384 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 76 161 0 ENST00000426263.3:c.747G>A p.Arg249= p.R249= ENST00000426263 NM_006516.2 249 cgG/cgA 0 +SLC35A5 UCSF GRCh37 3 112299912 112299912 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 75 193 0 ENST00000492406.1:c.948G>A p.Gln316= p.Q316= ENST00000492406 NM_017945.3 316 caG/caA 0 +SLC35B2 UCSF GRCh37 6 44223172 44223172 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 92 161 0 ENST00000393812.3:c.570C>T p.Ser190= p.S190= ENST00000393812 NM_178148.2 190 agC/agT 0 +SLC35C2 UCSF GRCh37 20 44979157 44979157 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 45 106 0 ENST00000243896.2:c.974G>A p.Gly325Asp p.G325D ENST00000243896 NM_173179.3 325 gGt/gAt 0 +SLC35D2 UCSF GRCh37 9 99106194 99106194 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 155 126 318 0 ENST00000253270.7:c.676C>T p.Leu226= p.L226= ENST00000253270 NM_007001.2 226 Ctg/Ttg 0 +SLC36A3 UCSF GRCh37 5 150663711 150663711 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 101 237 0 ENST00000335230.3:c.868G>A p.Gly290Arg p.G290R ENST00000335230 NM_181774.3 290 Ggg/Agg 0 +SLC38A1 UCSF GRCh37 12 46582843 46582843 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 95 204 0 ENST00000398637.5:c.1374C>T p.Phe458= p.F458= ENST00000398637 NM_030674.3 458 ttC/ttT 0 +SLC38A7 UCSF GRCh37 16 58701337 58701337 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 61 103 0 ENST00000219320.4:c.1341C>T p.Ile447= p.I447= ENST00000219320 NM_018231.1 447 atC/atT 0 +SLC39A1 UCSF GRCh37 1 153932594 153932594 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 64 125 0 ENST00000310483.6:c.955C>T p.Leu319= p.L319= ENST00000310483 NM_014437.4 319 Ctg/Ttg 0 +SLC39A13 UCSF GRCh37 11 47436366 47436366 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 40 138 0 ENST00000362021.4:c.825C>T p.Asp275= p.D275= ENST00000362021 NM_001128225.2 275 gaC/gaT 0 +SLC39A4 UCSF GRCh37 8 145641309 145641309 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 4 19 0 ENST00000301305.3:c.359C>T p.Ala120Val p.A120V ENST00000301305 NM_130849.3 120 gCc/gTc 0 +SLC41A2 UCSF GRCh37 12 105239662 105239662 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 66 131 0 ENST00000258538.3:c.1346C>T p.Pro449Leu p.P449L ENST00000258538 NM_032148.3 449 cCc/cTc 0 +SLC44A2 UCSF GRCh37 19 10748407 10748407 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 76 200 0 ENST00000335757.5:c.1679G>A p.Arg560Lys p.R560K ENST00000335757 560 aGg/aAg 0 +SLC44A4 UCSF GRCh37 6 31831431 31831431 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 23 42 0 ENST00000229729.6:c.2106C>T p.Pro702= p.P702= ENST00000229729 NM_025257.2 702 ccC/ccT 0 +SLC4A4 UCSF GRCh37 4 72429552 72429552 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 151 110 223 0 ENST00000264485.5:c.3142C>T p.Pro1048Ser p.P1048S ENST00000264485 NM_001098484.2 1048 Cca/Tca 0 +SLC4A4 UCSF GRCh37 4 72432773 72432773 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 49 138 0 ENST00000264485.5:c.*9C>T *3* ENST00000264485 NM_001098484.2 0 +SLC5A10 UCSF GRCh37 17 18922759 18922759 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 16 48 0 ENST00000395645.3:c.1265G>A p.Gly422Asp p.G422D ENST00000395645 NM_001042450.2 422 gGc/gAc 0 +SLC5A3 UCSF GRCh37 21 35469301 35469301 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 155 99 238 0 ENST00000381151.3:c.1804G>A p.Asp602Asn p.D602N ENST00000381151 602 Gat/Aat 0 +SLC5A5 UCSF GRCh37 19 17986914 17986914 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 40 79 0 ENST00000222248.3:c.697G>A p.Asp233Asn p.D233N ENST00000222248 NM_000453.2 233 Gac/Aac 0 +SLC5A8 UCSF GRCh37 12 101603315 101603315 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 27 48 0 ENST00000536262.2:c.312C>T p.Leu104= p.L104= ENST00000536262 NM_145913.3 104 ctC/ctT 0 +SLC6A18 UCSF GRCh37 5 1243822 1243822 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 41 76 0 ENST00000324642.3:c.1284C>T p.Pro428= p.P428= ENST00000324642 NM_182632.2 428 ccC/ccT 0 +SLC6A3 UCSF GRCh37 5 1422087 1422087 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 62 125 0 ENST00000270349.9:c.696C>T p.Asp232= p.D232= ENST00000270349 NM_001044.4 232 gaC/gaT 0 +SLC6A5 UCSF GRCh37 11 20628611 20628611 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 36 86 0 ENST00000525748.1:c.738C>T p.Phe246= p.F246= ENST00000525748 NM_004211.3 246 ttC/ttT 0 +SLC9A10 UCSF GRCh37 3 111993771 111993771 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 158 109 209 0 ENST00000305815.5:c.586C>T p.Leu196= p.L196= ENST00000305815 NM_183061.1 196 Cta/Tta 0 +SLC9A3 UCSF GRCh37 5 483527 483527 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 3 23 0 ENST00000264938.3:c.1003G>A p.Val335Met p.V335M ENST00000264938 NM_004174.2 335 Gtg/Atg 0 +SLC9A5 UCSF GRCh37 16 67300129 67300129 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 39 80 0 ENST00000299798.11:c.2218+1G>A p.X740_splice ENST00000299798 NM_004594.2 0 +SLFN5 UCSF GRCh37 17 33591579 33591579 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 87 211 0 ENST00000299977.4:c.1516G>A p.Val506Ile p.V506I ENST00000299977 NM_144975.3 506 Gtt/Att 0 +SLIT1 UCSF GRCh37 10 98945240 98945240 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 8 31 0 ENST00000266058.4:c.192G>A p.Glu64= p.E64= ENST00000266058 NM_003061.2 64 gaG/gaA 0 +SLITRK5 UCSF GRCh37 13 88328840 88328840 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 45 120 0 ENST00000325089.6:c.1197G>A p.Glu399= p.E399= ENST00000325089 NM_015567.1 399 gaG/gaA 0 +SLX4 UCSF GRCh37 16 3647861 3647861 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 76 132 0 ENST00000294008.3:c.1303G>A p.Gly435Ser p.G435S ENST00000294008 NM_032444.2 435 Ggt/Agt 0 +SMAP2 UCSF GRCh37 1 40882730 40882730 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 44 41 59 0 ENST00000372718.3:c.1126G>A p.Val376Ile p.V376I ENST00000372718 NM_022733.2 376 Gtc/Atc 0 +SMARCA4 UCSF GRCh37 19 11144114 11144114 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 99 70 162 0 ENST00000344626.4:c.3695G>A p.Gly1232Asp p.G1232D ENST00000344626 NM_003072.3 1232 gGc/gAc 0 +SMARCA4 UCSF GRCh37 19 11145748 11145748 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 17 30 0 ENST00000344626.4:c.4110C>T p.Gly1370= p.G1370= ENST00000344626 NM_003072.3 1370 ggC/ggT 0 +SMARCAD1 UCSF GRCh37 4 95173835 95173835 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 23 62 0 ENST00000354268.4:c.958C>T p.Pro320Ser p.P320S ENST00000354268 320 Cct/Tct 0 +SMARCB1 UCSF GRCh37 22 24145540 24145540 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 67 190 0 ENST00000263121.7:c.559G>A p.Val187Ile p.V187I ENST00000263121 NM_003073.3 187 Gtc/Atc 0 +SMC4 UCSF GRCh37 3 160130152 160130152 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 86 161 0 ENST00000344722.5:c.891C>T p.Ala297= p.A297= ENST00000344722 NM_005496.3 297 gcC/gcT 0 +SMG1 UCSF GRCh37 16 18896968 18896968 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 360 147 308 0 ENST00000446231.2:c.843G>A p.Gln281= p.Q281= ENST00000446231 281 caG/caA 0 +SMG6 UCSF GRCh37 17 2203390 2203390 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 91 200 0 ENST00000263073.6:c.657G>A p.Arg219= p.R219= ENST00000263073 NM_017575.4 219 agG/agA 0 +SMG9 UCSF GRCh37 19 44251867 44251867 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 8 17 0 ENST00000270066.6:c.408G>A p.Glu136= p.E136= ENST00000270066 NM_019108.2 136 gaG/gaA 0 +SMYD2 UCSF GRCh37 1 214504359 214504359 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 80 215 0 ENST00000366957.5:c.883G>A p.Val295Ile p.V295I ENST00000366957 NM_020197.2 295 Gtc/Atc 0 +SNAP25 UCSF GRCh37 20 10279964 10279964 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 96 235 0 ENST00000254976.2:c.456G>A p.Gln152= p.Q152= ENST00000254976 NM_130811.2 152 caG/caA 0 +SNAPC4 UCSF GRCh37 9 139279233 139279233 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 56 184 0 ENST00000298532.2:c.1359G>A p.Lys453= p.K453= ENST00000298532 NM_003086.2 453 aaG/aaA 0 +SNCAIP UCSF GRCh37 5 121787009 121787009 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 79 169 0 ENST00000261368.8:c.2467G>A p.Val823Met p.V823M ENST00000261368 NM_005460.2 823 Gtg/Atg 0 +SNCAIP UCSF GRCh37 5 121758579 121758579 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 62 143 0 ENST00000261368.8:c.147G>A p.Trp49Ter p.W49* ENST00000261368 NM_005460.2 49 tgG/tgA 0 +SND1 UCSF GRCh37 7 127343361 127343361 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 60 116 0 ENST00000354725.3:c.824G>A p.Gly275Asp p.G275D ENST00000354725 NM_014390.2 275 gGt/gAt 0 +SNRNP25 UCSF GRCh37 16 105853 105853 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 28 63 0 ENST00000383018.3:c.237G>A p.Glu79= p.E79= ENST00000383018 NM_024571.3 79 gaG/gaA 0 +SNRPA1 UCSF GRCh37 15 101826467 101826467 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 59 154 0 ENST00000254193.6:c.491G>A p.Gly164Asp p.G164D ENST00000254193 NM_003090.2 164 gGc/gAc 0 +SNRPB UCSF GRCh37 20 2448337 2448337 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 71 169 0 ENST00000438552.2:c.71G>A p.Gly24Asp p.G24D ENST00000438552 NM_198216.1 24 gGc/gAc 0 +SNTG1 UCSF GRCh37 8 51415431 51415431 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 61 108 0 ENST00000518864.1:c.457G>A p.Asp153Asn p.D153N ENST00000518864 153 Gat/Aat 0 +SNW1 UCSF GRCh37 14 78198932 78198932 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 67 172 0 ENST00000261531.7:c.787C>T p.Pro263Ser p.P263S ENST00000261531 NM_012245.2 263 Cca/Tca 0 +SNX24 UCSF GRCh37 5 122281781 122281781 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 48 90 0 ENST00000261369.4:c.176C>T p.Pro59Leu p.P59L ENST00000261369 NM_014035.2 59 cCt/cTt 0 +SNX27 UCSF GRCh37 1 151638437 151638437 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 116 58 159 0 ENST00000458013.2:c.935G>A p.Ser312Asn p.S312N ENST00000458013 312 aGt/aAt 0 +SNX33 UCSF GRCh37 15 75949512 75949512 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 77 156 0 ENST00000308527.5:c.1681G>A p.Gly561Ser p.G561S ENST00000308527 NM_153271.1 561 Ggc/Agc 0 +SOCS6 UCSF GRCh37 18 67992170 67992170 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 88 207 0 ENST00000397942.3:c.266G>A p.Gly89Asp p.G89D ENST00000397942 NM_004232.3 89 gGc/gAc 0 +SON UCSF GRCh37 21 34945614 34945614 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 69 161 0 ENST00000356577.4:c.6886G>A p.Asp2296Asn p.D2296N ENST00000356577 NM_138927.2 2296 Gat/Aat 0 +SORCS1 UCSF GRCh37 10 108357112 108357112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 41 83 0 ENST00000263054.6:c.3262G>A p.Ala1088Thr p.A1088T ENST00000263054 NM_001206570.1 1088 Gcg/Acg 0 +SORCS3 UCSF GRCh37 10 106802835 106802835 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 90 207 0 ENST00000369701.3:c.977G>A p.Gly326Glu p.G326E ENST00000369701 NM_014978.1 326 gGa/gAa 0 +SOX2 UCSF GRCh37 3 181430304 181430304 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 44 87 0 ENST00000325404.1:c.156C>T p.Ser52= p.S52= ENST00000325404 NM_003106.3 52 tcC/tcT 0 +SOX8 UCSF GRCh37 16 1035317 1035317 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 10 21 0 ENST00000293894.3:c.1272C>T p.Ala424= p.A424= ENST00000293894 NM_014587.3 424 gcC/gcT 0 +SPAG5 UCSF GRCh37 17 26905492 26905492 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 64 146 0 ENST00000321765.5:c.3253G>A p.Glu1085Lys p.E1085K ENST00000321765 NM_006461.3 1085 Gag/Aag 0 +SPATA19 UCSF GRCh37 11 133711925 133711925 + splice_region_variant,3_prime_UTR_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 64 122 0 ENST00000299140.3:c.*9G>A p.X3_splice ENST00000299140 NM_174927.1 0 +SPATA4 UCSF GRCh37 4 177113852 177113852 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 59 149 0 ENST00000280191.2:c.614C>T p.Thr205Ile p.T205I ENST00000280191 NM_144644.2 205 aCc/aTc 0 +SPATA4 UCSF GRCh37 4 177113937 177113937 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 43 101 0 ENST00000280191.2:c.529C>T p.Pro177Ser p.P177S ENST00000280191 NM_144644.2 177 Ccc/Tcc 0 +SPDYE1 UCSF GRCh37 7 44047166 44047166 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 153 84 326 0 ENST00000258704.3:c.932C>T p.Ser311Phe p.S311F ENST00000258704 NM_175064.2 311 tCc/tTc 0 +SPEN UCSF GRCh37 1 16255398 16255398 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 220 163 308 0 ENST00000375759.3:c.2663G>A p.Gly888Glu p.G888E ENST00000375759 NM_015001.2 888 gGa/gAa 0 +SPEN UCSF GRCh37 1 16264397 16264397 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 78 160 0 ENST00000375759.3:c.10600G>A p.Ala3534Thr p.A3534T ENST00000375759 NM_015001.2 3534 Gcc/Acc 0 +SPEN UCSF GRCh37 1 16264466 16264466 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 70 103 0 ENST00000375759.3:c.10669G>A p.Ala3557Thr p.A3557T ENST00000375759 NM_015001.2 3557 Gca/Aca 0 +SPG11 UCSF GRCh37 15 44887641 44887641 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 49 116 0 ENST00000261866.7:c.4451C>T p.Ser1484Phe p.S1484F ENST00000261866 NM_025137.3 1484 tCt/tTt 0 +SPG20 UCSF GRCh37 13 36886372 36886372 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 111 208 0 ENST00000355182.4:c.1643G>A p.Gly548Glu p.G548E ENST00000355182 NM_001142294.1 548 gGa/gAa 0 +SPHK1 UCSF GRCh37 17 74382100 74382100 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 9 35 0 ENST00000392496.3:c.45C>T p.Cys15= p.C15= ENST00000392496 NM_001142602.1 15 tgC/tgT 0 +SPHKAP UCSF GRCh37 2 228883796 228883796 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 55 133 0 ENST00000392056.3:c.1774G>A p.Ala592Thr p.A592T ENST00000392056 NM_001142644.1 592 Gca/Aca 0 +SPINK5 UCSF GRCh37 5 147478850 147478850 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 51 111 0 ENST00000256084.7:c.1064G>A p.Arg355Lys p.R355K ENST00000256084 NM_006846.3 355 aGa/aAa 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 133 87 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +SPINK8 UCSF GRCh37 3 48351427 48351427 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 33 78 0 ENST00000434006.1:c.249G>A p.Gly83= p.G83= ENST00000434006 NM_001080525.1 83 ggG/ggA 0 +SPIRE1 UCSF GRCh37 18 12546786 12546786 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 158 126 260 0 ENST00000409402.4:c.490G>A p.Val164Met p.V164M ENST00000409402 NM_001128626.1 164 Gtg/Atg 0 +SPIRE1 UCSF GRCh37 18 12464913 12464913 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 37 71 0 ENST00000409402.4:c.1449C>T p.Pro483= p.P483= ENST00000409402 NM_001128626.1 483 ccC/ccT 0 +SPNS1 UCSF GRCh37 16 28993726 28993726 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 44 134 0 ENST00000311008.11:c.1015C>T p.Leu339= p.L339= ENST00000311008 NM_032038.2 339 Ctg/Ttg 0 +SPRED1 UCSF GRCh37 15 38641642 38641642 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 83 125 0 ENST00000299084.4:c.602G>A p.Gly201Asp p.G201D ENST00000299084 NM_152594.2 201 gGc/gAc 0 +SPTAN1 UCSF GRCh37 9 131394412 131394412 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 22 52 0 ENST00000372731.4:c.6754C>T p.His2252Tyr p.H2252Y ENST00000372731 NM_003127.3 2252 Cac/Tac 0 +SPTAN1 UCSF GRCh37 9 131349977 131349977 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 45 108 0 ENST00000372731.4:c.2871G>A p.Arg957= p.R957= ENST00000372731 NM_003127.3 957 cgG/cgA 0 +SPTBN5 UCSF GRCh37 15 42179555 42179555 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 18 41 0 ENST00000320955.6:c.744G>A p.Glu248= p.E248= ENST00000320955 NM_016642.3 248 gaG/gaA 0 +SPZ1 UCSF GRCh37 5 79616573 79616573 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 97 251 0 ENST00000296739.4:c.539C>T p.Ala180Val p.A180V ENST00000296739 NM_032567.3 180 gCc/gTc 0 +SRCAP UCSF GRCh37 16 30722945 30722945 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 85 150 0 ENST00000262518.4:c.1372G>A p.Gly458Ser p.G458S ENST00000262518 NM_006662.2 458 Ggc/Agc 0 +SRCAP UCSF GRCh37 16 30724618 30724618 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 109 212 0 ENST00000262518.4:c.2220G>A p.Trp740Ter p.W740* ENST00000262518 NM_006662.2 740 tgG/tgA 0 +SRCIN1 UCSF GRCh37 17 36714548 36714548 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 36 79 0 ENST00000264659.7:c.2116G>A p.Asp706Asn p.D706N ENST00000264659 NM_025248.2 706 Gac/Aac 0 +SRCRB4D UCSF GRCh37 7 76027005 76027005 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 25 46 0 ENST00000275560.3:c.698G>A p.Gly233Glu p.G233E ENST00000275560 NM_080744.1 233 gGg/gAg 0 +SREBF1 UCSF GRCh37 17 17723659 17723659 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 31 82 0 ENST00000261646.5:c.268C>T p.Pro90Ser p.P90S ENST00000261646 NM_004176.4 90 Ccg/Tcg 0 +SREBF1 UCSF GRCh37 17 17723768 17723768 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 32 81 0 ENST00000261646.5:c.159G>A p.Gly53= p.G53= ENST00000261646 NM_004176.4 53 ggG/ggA 0 +SRGAP1 UCSF GRCh37 12 64536263 64536263 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 97 187 0 ENST00000355086.3:c.3069G>A p.Gln1023= p.Q1023= ENST00000355086 NM_020762.2 1023 caG/caA 0 +SRGAP3 UCSF GRCh37 3 9097938 9097938 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 234 62 161 0 ENST00000383836.3:c.1104C>T p.Thr368= p.T368= ENST00000383836 NM_014850.3 368 acC/acT 0 +SRGAP3 UCSF GRCh37 3 9099983 9099983 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 294 79 179 0 ENST00000383836.3:c.975C>T p.Val325= p.V325= ENST00000383836 NM_014850.3 325 gtC/gtT 0 +SRL UCSF GRCh37 16 4247852 4247852 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 57 144 0 ENST00000399609.3:c.324C>T p.Thr108= p.T108= ENST00000399609 NM_001098814.1 108 acC/acT 0 +SRRM2 UCSF GRCh37 16 2813421 2813421 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 347 120 279 0 ENST00000301740.8:c.2892G>A p.Leu964= p.L964= ENST00000301740 NM_016333.3 964 ttG/ttA 0 +SRRM3 UCSF GRCh37 7 75914999 75914999 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 13 29 0 ENST00000326382.8:c.*6G>A *2* ENST00000326382 NM_001110199.1 0 +SSBP4 UCSF GRCh37 19 18542824 18542824 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 7 42 0 ENST00000270061.7:c.580G>A p.Gly194Ser p.G194S ENST00000270061 NM_032627.4 194 Ggc/Agc 0 +SSH3 UCSF GRCh37 11 67074528 67074528 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 46 74 0 ENST00000308127.4:c.480C>T p.Thr160= p.T160= ENST00000308127 NM_017857.3 160 acC/acT 0 +SSPO UCSF GRCh37 7 149504001 149504001 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 9 27 0 ENST00000378016.2:n.8825G>A *2942* ENST00000378016 0 +SSTR4 UCSF GRCh37 20 23017130 23017130 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 51 104 0 ENST00000255008.3:c.1010G>A p.Gly337Glu p.G337E ENST00000255008 NM_001052.2 337 gGa/gAa 0 +SSX1 UCSF GRCh37 X 48125757 48125757 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 178 195 0 ENST00000376919.3:c.502C>T p.Leu168= p.L168= ENST00000376919 NM_005635.3 168 Ctg/Ttg 0 +ST3GAL4 UCSF GRCh37 11 126277205 126277205 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 106 235 0 ENST00000392669.2:c.241C>T p.Pro81Ser p.P81S ENST00000392669 NM_001254758.1 81 Cca/Tca 0 +STAB1 UCSF GRCh37 3 52540864 52540864 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 27 38 0 ENST00000321725.6:c.1987G>A p.Ala663Thr p.A663T ENST00000321725 NM_015136.2 663 Gcg/Acg 0 +STAB1 UCSF GRCh37 3 52536691 52536691 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 39 73 0 ENST00000321725.6:c.531G>A p.Gly177= p.G177= ENST00000321725 NM_015136.2 177 ggG/ggA 0 +STAG3 UCSF GRCh37 7 99778250 99778250 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 198 127 286 0 ENST00000317296.5:c.71C>T p.Ala24Val p.A24V ENST00000317296 NM_012447.2 24 gCc/gTc 0 +STARD10 UCSF GRCh37 11 72470348 72470348 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 61 149 0 ENST00000334805.6:c.286G>A p.Asp96Asn p.D96N ENST00000334805 NM_006645.2 96 Gac/Aac 0 +STARD9 UCSF GRCh37 15 42930238 42930238 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 81 184 0 ENST00000290607.7:c.399G>A p.Arg133= p.R133= ENST00000290607 NM_020759.2 133 agG/agA 0 +STAT3 UCSF GRCh37 17 40475363 40475363 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 83 180 0 ENST00000264657.5:c.1663G>A p.Ala555Thr p.A555T ENST00000264657 NM_139276.2 555 Gct/Act 0 +STAT5B UCSF GRCh37 17 40354446 40354446 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 25 62 0 ENST00000293328.3:c.2149G>A p.Asp717Asn p.D717N ENST00000293328 NM_012448.3 717 Gat/Aat 0 +STIM1 UCSF GRCh37 11 4112853 4112853 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 62 158 0 ENST00000300737.4:c.1883C>T p.Ser628Phe p.S628F ENST00000300737 NM_003156.3 628 tCt/tTt 0 +STK11IP UCSF GRCh37 2 220471515 220471515 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 71 161 0 ENST00000295641.10:c.1102C>T p.Pro368Ser p.P368S ENST00000295641 NM_052902.2 368 Cct/Tct 0 +STK32A UCSF GRCh37 5 146763487 146763487 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 90 208 0 ENST00000397936.3:c.1132C>T p.Leu378= p.L378= ENST00000397936 NM_001112724.1 378 Cta/Tta 0 +STOML3 UCSF GRCh37 13 39541032 39541032 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 92 169 0 ENST00000379631.4:c.806C>T p.Pro269Leu p.P269L ENST00000379631 NM_145286.2 269 cCc/cTc 0 +STON1 UCSF GRCh37 2 48809625 48809625 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 76 180 0 ENST00000309835.3:c.1853C>T p.Thr618Ile p.T618I ENST00000309835 618 aCt/aTt 0 +STXBP5 UCSF GRCh37 6 147646219 147646219 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 45 128 0 ENST00000321680.6:c.1927C>T p.Leu643= p.L643= ENST00000321680 NM_001127715.2 643 Ctg/Ttg 0 +SULT2A1 UCSF GRCh37 19 48387013 48387013 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 53 102 0 ENST00000222002.3:c.166C>T p.Leu56= p.L56= ENST00000222002 NM_003167.3 56 Ctg/Ttg 0 +SULT2B1 UCSF GRCh37 19 49100093 49100093 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 16 42 0 ENST00000201586.2:c.743C>T p.Ala248Val p.A248V ENST00000201586 NM_177973.1 248 gCc/gTc 0 +SVIL UCSF GRCh37 10 29756720 29756720 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 167 65 130 0 ENST00000355867.4:c.5928G>A p.Trp1976Ter p.W1976* ENST00000355867 NM_021738.2 1976 tgG/tgA 0 +SYCE1 UCSF GRCh37 10 135369349 135369349 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 50 110 0 ENST00000343131.5:c.654G>A p.Gly218= p.G218= ENST00000343131 NM_001143764.1 218 ggG/ggA 0 +SYCE2 UCSF GRCh37 19 13011406 13011406 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 126 89 193 0 ENST00000293695.7:c.363C>T p.His121= p.H121= ENST00000293695 NM_001105578.1 121 caC/caT 0 +SYNE1 UCSF GRCh37 6 152603061 152603061 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 60 47 116 0 ENST00000367255.5:c.18262T>C p.Tyr6088His p.Y6088H ENST00000367255 NM_182961.3 6088 Tat/Cat 0 +SYNE1 UCSF GRCh37 6 152545661 152545661 + stop_gained Nonsense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 71 205 0 ENST00000367255.5:c.21490G>T p.Glu7164Ter p.E7164* ENST00000367255 NM_182961.3 7164 Gaa/Taa 0 +SYNE2 UCSF GRCh37 14 64469624 64469624 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 86 186 0 ENST00000344113.4:c.3973C>T p.Leu1325= p.L1325= ENST00000344113 NM_015180.4 1325 Ctg/Ttg 0 +SYNGAP1 UCSF GRCh37 6 33412273 33412273 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 52 137 0 ENST00000418600.2:c.3461C>T p.Thr1154Ile p.T1154I ENST00000418600 NM_006772.2 1154 aCa/aTa 0 +SYNGR3 UCSF GRCh37 16 2042036 2042036 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 3 13 0 ENST00000248121.2:c.161G>A p.Gly54Asp p.G54D ENST00000248121 NM_004209.5 54 gGc/gAc 0 +SYNJ1 UCSF GRCh37 21 34038826 34038826 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 182 102 243 0 ENST00000433931.2:c.1986C>T p.Asn662= p.N662= ENST00000433931 NM_003895.3 662 aaC/aaT 0 +SYNJ2 UCSF GRCh37 6 158449942 158449942 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 50 160 0 ENST00000355585.4:c.369C>T p.Ile123= p.I123= ENST00000355585 NM_001178088.1 123 atC/atT 0 +SYT11 UCSF GRCh37 1 155838193 155838193 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 107 215 0 ENST00000368324.4:c.472C>T p.Leu158= p.L158= ENST00000368324 NM_152280.4 158 Cta/Tta 0 +SYT12 UCSF GRCh37 11 66816106 66816106 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 42 66 0 ENST00000393946.2:c.1144G>A p.Asp382Asn p.D382N ENST00000393946 382 Gac/Aac 0 +SYT3 UCSF GRCh37 19 51132555 51132555 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 16 32 0 ENST00000338916.4:c.1277G>A p.Gly426Asp p.G426D ENST00000338916 NM_032298.2 426 gGc/gAc 0 +SZT2 UCSF GRCh37 1 43907023 43907023 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 85 196 0 ENST00000562955.1:c.7312G>A p.Gly2438Ser p.G2438S ENST00000562955 NM_015284.3 2438 Ggc/Agc 0 +T UCSF GRCh37 6 166580152 166580152 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 59 150 0 ENST00000296946.2:c.399G>A p.Gly133= p.G133= ENST00000296946 NM_003181.3 133 ggG/ggA 0 +TAB3 UCSF GRCh37 X 30873508 30873508 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 4 33 43 0 ENST00000378933.1:c.274C>T p.Leu92Phe p.L92F ENST00000378933 NM_152787.3 92 Ctt/Ttt 0 +TACC2 UCSF GRCh37 10 123843783 123843783 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 47 120 0 ENST00000334433.3:c.1768G>A p.Asp590Asn p.D590N ENST00000334433 590 Gac/Aac 0 +TADA2A UCSF GRCh37 17 35802719 35802719 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 38 113 0 ENST00000394395.2:c.497C>T p.Ala166Val p.A166V ENST00000394395 NM_001166105.1 166 gCc/gTc 0 +TAF11 UCSF GRCh37 6 34846481 34846481 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 60 147 0 ENST00000361288.4:c.522G>A p.Glu174= p.E174= ENST00000361288 NM_005643.3 174 gaG/gaA 0 +TAF1L UCSF GRCh37 9 32635537 32635537 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 55 131 0 ENST00000242310.4:c.41C>T p.Thr14Ile p.T14I ENST00000242310 NM_153809.2 14 aCc/aTc 0 +TAF4B UCSF GRCh37 18 23866446 23866446 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 93 185 0 ENST00000269142.5:c.1573G>A p.Val525Ile p.V525I ENST00000269142 NM_005640.1 525 Gtt/Att 0 +TAGLN UCSF GRCh37 11 117074071 117074071 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 67 156 0 ENST00000278968.6:c.229G>A p.Val77Met p.V77M ENST00000278968 NM_001001522.1 77 Gtg/Atg 0 +TANK UCSF GRCh37 2 162061305 162061305 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 50 137 0 ENST00000259075.2:c.327+1G>A p.X109_splice ENST00000259075 NM_004180.2 0 +TAOK1 UCSF GRCh37 17 27857551 27857551 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 94 197 0 ENST00000261716.3:c.2275C>T p.Arg759Trp p.R759W ENST00000261716 NM_020791.2 759 Cgg/Tgg 0 +TAOK3 UCSF GRCh37 12 118639265 118639265 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 54 121 0 ENST00000392533.3:c.823G>A p.Asp275Asn p.D275N ENST00000392533 NM_016281.3 275 Gac/Aac 0 +TARDBP UCSF GRCh37 1 11082189 11082189 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 86 154 0 ENST00000240185.3:c.723G>A p.Gln241= p.Q241= ENST00000240185 NM_007375.3 241 caG/caA 0 +TAS2R20 UCSF GRCh37 12 11149806 11149806 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 185 155 326 0 ENST00000538986.1:c.669C>T p.Ile223= p.I223= ENST00000538986 NM_176889.2 223 atC/atT 0 +TASP1 UCSF GRCh37 20 13539702 13539702 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 85 180 0 ENST00000337743.4:c.628G>A p.Asp210Asn p.D210N ENST00000337743 NM_017714.2 210 Gac/Aac 0 +TBC1D10A UCSF GRCh37 22 30700641 30700641 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 18 33 96 0 ENST00000215790.7:c.210-22G>A *70* ENST00000215790 NM_031937.2 0 +TBC1D14 UCSF GRCh37 4 6925299 6925299 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 59 144 0 ENST00000409757.4:c.183C>T p.Leu61= p.L61= ENST00000409757 NM_020773.2 61 ctC/ctT 0 +TBC1D16 UCSF GRCh37 17 77984396 77984396 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 5 21 0 ENST00000310924.2:c.342G>A p.Arg114= p.R114= ENST00000310924 NM_019020.3 114 cgG/cgA 0 +TBC1D19 UCSF GRCh37 4 26585897 26585897 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 13 32 0 ENST00000264866.4:c.82C>T p.Leu28= p.L28= ENST00000264866 NM_018317.2 28 Ctg/Ttg 0 +TBC1D30 UCSF GRCh37 12 65230282 65230282 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 41 114 0 ENST00000539867.1:c.607C>T p.Leu203Phe p.L203F ENST00000539867 NM_015279.1 203 Ctt/Ttt 0 +TBC1D4 UCSF GRCh37 13 75866342 75866342 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 71 131 0 ENST00000377636.3:c.3382G>A p.Glu1128Lys p.E1128K ENST00000377636 NM_014832.2 1128 Gag/Aag 0 +TBC1D4 UCSF GRCh37 13 75894149 75894149 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 30 94 0 ENST00000377636.3:c.2222+1G>A p.X741_splice ENST00000377636 NM_014832.2 0 +TBC1D8 UCSF GRCh37 2 101648800 101648800 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 91 140 0 ENST00000376840.4:c.1821G>A p.Glu607= p.E607= ENST00000376840 607 gaG/gaA 0 +TBCCD1 UCSF GRCh37 3 186272541 186272541 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 50 96 0 ENST00000338733.5:c.1047-1G>A p.X349_splice ENST00000338733 NM_018138.3 0 +TBCD UCSF GRCh37 17 80739489 80739489 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 88 206 0 ENST00000355528.4:c.663G>A p.Lys221= p.K221= ENST00000355528 NM_005993.4 221 aaG/aaA 0 +TBX15 UCSF GRCh37 1 119474318 119474318 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 42 110 0 ENST00000369429.3:c.343G>A p.Val115Met p.V115M ENST00000369429 115 Gtg/Atg 0 +TBX5 UCSF GRCh37 12 114804055 114804055 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 83 142 0 ENST00000310346.4:c.897C>T p.Gly299= p.G299= ENST00000310346 NM_000192.3 299 ggC/ggT 0 +TBXAS1 UCSF GRCh37 7 139657524 139657524 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 68 141 0 ENST00000336425.5:c.780G>A p.Arg260= p.R260= ENST00000336425 260 agG/agA 0 +TCEAL5 UCSF GRCh37 X 102529174 102529174 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 123 137 0 ENST00000372680.1:c.318C>T p.Arg106= p.R106= ENST00000372680 NM_001012979.2 106 cgC/cgT 0 +TCEB3B UCSF GRCh37 18 44561448 44561448 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 32 87 0 ENST00000332567.4:c.188G>A p.Gly63Asp p.G63D ENST00000332567 NM_016427.2 63 gGc/gAc 0 +TCERG1 UCSF GRCh37 5 145838501 145838501 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 96 205 0 ENST00000296702.5:c.493G>A p.Val165Ile p.V165I ENST00000296702 NM_006706.3 165 Gtt/Att 0 +TCF25 UCSF GRCh37 16 89958648 89958648 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 23 46 0 ENST00000263346.8:c.662C>T p.Thr221Ile p.T221I ENST00000263346 NM_014972.2 221 aCc/aTc 0 +TCHH UCSF GRCh37 1 152084192 152084192 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 27 164 0 ENST00000368804.1:c.1501G>A p.Glu501Lys p.E501K ENST00000368804 NM_007113.3 501 Gag/Aag 0 +TCHH UCSF GRCh37 1 152084210 152084210 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 16 163 0 ENST00000368804.1:c.1483G>A p.Glu495Lys p.E495K ENST00000368804 NM_007113.3 495 Gag/Aag 0 +TCHH UCSF GRCh37 1 152084193 152084194 + inframe_insertion In_Frame_Ins INS - - CTGCTGCTCGCGCCTCTT NOVEL P18_Rec Untested WXS Illumina HiSeq 10 0 ENST00000368804.1:c.1499_1500insAAGAGGCGCGAGCAGCAG p.Gln500_Glu501insArgGlyAlaSerSerArg p.Q500_E501insRGASSR ENST00000368804 NM_007113.3 500 cag/caAAGAGGCGCGAGCAGCAGg 0 +TCP10L2 UCSF GRCh37 6 167592009 167592009 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 350 75 415 0 ENST00000366832.2:c.636G>A p.Arg212= p.R212= ENST00000366832 NM_001145121.1 212 cgG/cgA 0 +TCTN1 UCSF GRCh37 12 111078207 111078207 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 65 105 0 ENST00000551590.1:c.863C>T p.Ser288Phe p.S288F ENST00000551590 288 tCc/tTc 0 +TDRD1 UCSF GRCh37 10 115991270 115991270 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 41 100 0 ENST00000251864.2:c.3564C>T p.Pro1188= p.P1188= ENST00000251864 NM_198795.1 1188 ccC/ccT 0 +TDRD9 UCSF GRCh37 14 104472730 104472730 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 174 119 284 0 ENST00000409874.4:c.1718G>A p.Gly573Glu p.G573E ENST00000409874 NM_153046.2 573 gGa/gAa 0 +TDRD9 UCSF GRCh37 14 104482389 104482389 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 58 123 0 ENST00000409874.4:c.2295G>A p.Arg765= p.R765= ENST00000409874 NM_153046.2 765 agG/agA 0 +TEC 7006 UCSF GRCh37 4 48147290 48147290 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 112 67 145 0 ENST00000381501.3:c.1276G>A p.Val426Met p.V426M ENST00000381501 NM_003215.2 426 Gtg/Atg 0 +TECTA UCSF GRCh37 11 120989349 120989349 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 105 195 0 ENST00000264037.2:c.1125C>T p.Val375= p.V375= ENST00000264037 NM_005422.2 375 gtC/gtT 0 +TECTA UCSF GRCh37 11 120996226 120996226 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 109 214 0 ENST00000264037.2:c.1419C>T p.Leu473= p.L473= ENST00000264037 NM_005422.2 473 ctC/ctT 0 +TERF1 UCSF GRCh37 8 73958219 73958219 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 147 93 206 0 ENST00000276603.5:c.1167G>A p.Lys389= p.K389= ENST00000276603 NM_017489.2 389 aaG/aaA 0 +TEX11 UCSF GRCh37 X 70080787 70080787 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 49 55 0 ENST00000344304.3:c.290-1G>A p.X97_splice ENST00000344304 0 +TEX19 UCSF GRCh37 17 80320513 80320513 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 53 126 0 ENST00000333437.4:c.487C>T p.Pro163Ser p.P163S ENST00000333437 NM_207459.3 163 Cct/Tct 0 +TFAM UCSF GRCh37 10 60146021 60146021 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 122 88 182 0 ENST00000487519.1:c.143G>A p.Ser48Asn p.S48N ENST00000487519 NM_003201.2 48 aGt/aAt 0 +TFF2 UCSF GRCh37 21 43771060 43771060 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.006,1000g2011may_all_0.0182,snp132_rs7277409 P18_Rec Untested WXS Illumina HiSeq 34 37 64 0 ENST00000291526.4:c.7C>T p.Arg3Trp p.R3W ENST00000291526 NM_005423.4 3 Cgg/Tgg 0 +TFR2 UCSF GRCh37 7 100229785 100229785 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 56 167 0 ENST00000223051.3:c.886C>T p.Leu296Phe p.L296F ENST00000223051 NM_003227.3 296 Ctc/Ttc 0 +TGFBR2 UCSF GRCh37 3 30713734 30713734 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 104 208 0 ENST00000295754.5:c.1059C>T p.Ser353= p.S353= ENST00000295754 NM_003242.5 353 tcC/tcT 0 +TGM3 UCSF GRCh37 20 2293603 2293603 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 128 118 205 0 ENST00000381458.5:c.600C>T p.Arg200= p.R200= ENST00000381458 NM_003245.3 200 cgC/cgT 0 +TH1L UCSF GRCh37 20 57564990 57564990 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 49 90 0 ENST00000602795.1:c.789G>A p.Gly263= p.G263= ENST00000602795 NM_198976.2 263 ggG/ggA 0 +THBS3 UCSF GRCh37 1 155170289 155170289 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 142 116 224 0 ENST00000368378.3:c.1661A>G p.Asp554Gly p.D554G ENST00000368378 NM_007112.4 554 gAt/gGt 0 +THBS3 UCSF GRCh37 1 155171292 155171292 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 58 90 0 ENST00000368378.3:c.1245C>T p.Ala415= p.A415= ENST00000368378 NM_007112.4 415 gcC/gcT 0 +THOC5 UCSF GRCh37 22 29916062 29916062 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 38 98 0 ENST00000397871.1:c.1309C>T p.Leu437= p.L437= ENST00000397871 NM_001002879.1 437 Cta/Tta 0 +THSD7B UCSF GRCh37 2 138030196 138030196 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 111 237 0 ENST00000272643.3:c.2360G>A p.Arg787Lys p.R787K ENST00000272643 787 aGa/aAa 0 +THUMPD3 UCSF GRCh37 3 9408637 9408637 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 299 63 170 0 ENST00000345094.3:c.298G>A p.Glu100Lys p.E100K ENST00000345094 NM_001114092.1 100 Gag/Aag 0 +TIE1 UCSF GRCh37 1 43772556 43772556 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 57 113 0 ENST00000372476.3:c.530G>A p.Arg177Gln p.R177Q ENST00000372476 NM_005424.4 177 cGg/cAg 0 +TIGIT UCSF GRCh37 3 114026946 114026946 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 105 271 0 ENST00000383671.3:c.703G>A p.Gly235Ser p.G235S ENST00000383671 NM_173799.3 235 Ggt/Agt 0 +TIMM50 UCSF GRCh37 19 39971203 39971203 + upstream_gene_variant 5'Flank SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 61 134 0 ENST00000607714 0 +TIMP1 UCSF GRCh37 X 47442895 47442895 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 70 68 0 ENST00000218388.4:c.81C>T p.Val27= p.V27= ENST00000218388 NM_003254.2 27 gtC/gtT 0 +TINAG UCSF GRCh37 6 54173386 54173386 + missense_variant Missense_Mutation SNP T T G NOVEL P18_Rec Untested WXS Illumina HiSeq 58 29 73 0 ENST00000259782.4:c.38T>G p.Leu13Arg p.L13R ENST00000259782 NM_014464.3 13 cTt/cGt 0 +TINAGL1 UCSF GRCh37 1 32050857 32050857 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 97 164 0 ENST00000271064.7:c.963C>T p.Arg321= p.R321= ENST00000271064 NM_022164.2 321 cgC/cgT 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 64 44 79 0 ENST00000541714.2:c.1372G>C p.Val458Leu p.V458L ENST00000541714 NM_001267560.1 458 Gtg/Ctg 0 +TKT UCSF GRCh37 3 53265544 53265544 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 43 107 0 ENST00000423525.2:c.771G>A p.Trp257Ter p.W257* ENST00000423525 NM_001135055.2 257 tgG/tgA 0 +TLE3 UCSF GRCh37 15 70347554 70347554 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 63 127 0 ENST00000558939.1:c.1421C>T p.Pro474Leu p.P474L ENST00000558939 NM_001282979.1 474 cCg/cTg 0 +TLE6 UCSF GRCh37 19 2989107 2989107 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 47 124 0 ENST00000246112.4:c.789C>T p.Ala263= p.A263= ENST00000246112 NM_001143986.1 263 gcC/gcT 0 +TLN2 UCSF GRCh37 15 63125806 63125806 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 70 178 0 ENST00000306829.6:c.7106G>A p.Arg2369Lys p.R2369K ENST00000306829 NM_015059.2 2369 aGg/aAg 0 +TM9SF4 UCSF GRCh37 20 30737484 30737484 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 50 63 0 ENST00000398022.2:c.1002C>T p.Val334= p.V334= ENST00000398022 NM_014742.3 334 gtC/gtT 0 +TMBIM4 UCSF GRCh37 12 66539731 66539731 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 55 135 0 ENST00000358230.3:c.354C>T p.Phe118= p.F118= ENST00000358230 NM_016056.2 118 ttC/ttT 0 +TMC8 UCSF GRCh37 17 76134223 76134223 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 50 105 0 ENST00000318430.5:c.1487C>T p.Pro496Leu p.P496L ENST00000318430 NM_152468.4 496 cCc/cTc 0 +TMEM109 UCSF GRCh37 11 60687263 60687263 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 112 202 0 ENST00000227525.3:c.98C>T p.Ala33Val p.A33V ENST00000227525 NM_024092.2 33 gCc/gTc 0 +TMEM115 UCSF GRCh37 3 50395655 50395655 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.00097 P18_Rec Untested WXS Illumina HiSeq 111 89 165 0 ENST00000266025.3:c.840C>T p.Ala280= p.A280= ENST00000266025 NM_007024.4 280 gcC/gcT 0 +TMEM131 UCSF GRCh37 2 98409175 98409175 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 68 158 0 ENST00000186436.5:c.3818G>A p.Gly1273Asp p.G1273D ENST00000186436 NM_015348.1 1273 gGt/gAt 0 +TMEM132A UCSF GRCh37 11 60694802 60694802 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 54 135 0 ENST00000453848.2:c.227C>T p.Ser76Phe p.S76F ENST00000453848 76 tCc/tTc 0 +TMEM132C UCSF GRCh37 12 129178440 129178440 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 68 159 0 ENST00000435159.2:c.1516G>A p.Val506Met p.V506M ENST00000435159 NM_001136103.2 506 Gtg/Atg 0 +TMEM143 UCSF GRCh37 19 48845943 48845943 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 37 76 0 ENST00000293261.3:c.819G>A p.Thr273= p.T273= ENST00000293261 NM_018273.2 273 acG/acA 0 +TMEM151B UCSF GRCh37 6 44243428 44243428 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 4 17 0 ENST00000451188.2:c.865G>A p.Asp289Asn p.D289N ENST00000451188 NM_001137560.1 289 Gac/Aac 0 +TMEM164 UCSF GRCh37 X 109247135 109247135 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 82 93 0 ENST00000372068.2:c.133G>A p.Val45Ile p.V45I ENST00000372068 NM_032227.3 45 Gtc/Atc 0 +TMEM165 UCSF GRCh37 4 56290810 56290810 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 40 97 0 ENST00000381334.5:c.898G>A p.Val300Met p.V300M ENST00000381334 NM_018475.4 300 Gtg/Atg 0 +TMEM173 UCSF GRCh37 5 138858022 138858022 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 111 246 0 ENST00000330794.4:c.592C>T p.Leu198= p.L198= ENST00000330794 NM_198282.2 198 Ctg/Ttg 0 +TMEM176A UCSF GRCh37 7 150501561 150501561 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 51 121 0 ENST00000004103.3:c.666+1G>A p.X222_splice ENST00000004103 NM_018487.2 0 +TMEM177 UCSF GRCh37 2 120439314 120439314 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 45 156 0 ENST00000272521.6:c.885G>A p.Arg295= p.R295= ENST00000272521 NM_030577.2 295 cgG/cgA 0 +TMEM181 UCSF GRCh37 6 158957729 158957729 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 9 19 0 ENST00000367090.3:c.251G>A p.Gly84Asp p.G84D ENST00000367090 NM_020823.1 84 gGt/gAt 0 +TMEM207 UCSF GRCh37 3 190167548 190167548 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 66 139 0 ENST00000354905.2:c.51G>A p.Gly17= p.G17= ENST00000354905 NM_207316.1 17 ggG/ggA 0 +TMEM209 UCSF GRCh37 7 129841783 129841783 + synonymous_variant Silent SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 240 99 216 0 ENST00000397622.2:c.480T>C p.Thr160= p.T160= ENST00000397622 NM_032842.3 160 acT/acC 0 +TMEM214 UCSF GRCh37 2 27258058 27258058 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 51 99 0 ENST00000238788.9:c.407G>A p.Gly136Glu p.G136E ENST00000238788 NM_017727.4 136 gGa/gAa 0 +TMEM38A UCSF GRCh37 19 16791263 16791263 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 199 139 310 0 ENST00000187762.2:c.337C>T p.Pro113Ser p.P113S ENST00000187762 NM_024074.1 113 Cct/Tct 0 +TMEM39A UCSF GRCh37 3 119156784 119156784 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 59 141 0 ENST00000319172.5:c.742C>T p.Leu248= p.L248= ENST00000319172 NM_018266.2 248 Cta/Tta 0 +TMEM44 UCSF GRCh37 3 194343978 194343978 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 40 102 0 ENST00000392432.2:c.587C>T p.Ser196Phe p.S196F ENST00000392432 NM_001166305.1 196 tCt/tTt 0 +TMEM63B UCSF GRCh37 6 44117599 44117599 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 16 21 0 ENST00000259746.9:c.1417C>T p.Pro473Ser p.P473S ENST00000259746 473 Ccc/Tcc 0 +TMEM63C UCSF GRCh37 14 77705765 77705765 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 37 70 0 ENST00000298351.4:c.736C>T p.Pro246Ser p.P246S ENST00000298351 NM_020431.2 246 Cca/Tca 0 +TMEM85 UCSF GRCh37 15 34520724 34520724 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 213 152 310 0 ENST00000267750.4:c.450G>A p.Lys150= p.K150= ENST00000267750 NM_016454.2 150 aaG/aaA 0 +TMF1 UCSF GRCh37 3 69092917 69092917 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 70 135 0 ENST00000398559.2:c.1562G>A p.Arg521Lys p.R521K ENST00000398559 521 aGa/aAa 0 +TMPRSS11A UCSF GRCh37 4 68795751 68795751 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 77 189 0 ENST00000334830.7:c.337G>A p.Glu113Lys p.E113K ENST00000334830 113 Gaa/Aaa 0 +TMPRSS11D UCSF GRCh37 4 68688127 68688127 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 127 92 226 0 ENST00000283916.6:c.1185G>A p.Leu395= p.L395= ENST00000283916 NM_004262.2 395 ctG/ctA 0 +TMPRSS13 UCSF GRCh37 11 117784494 117784494 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 55 119 0 ENST00000524993.1:c.807G>A p.Glu269= p.E269= ENST00000524993 NM_001077263.2 269 gaG/gaA 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 125 85 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TMPRSS3 UCSF GRCh37 21 43796669 43796669 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 53 98 0 ENST00000291532.3:c.1175G>A p.Gly392Asp p.G392D ENST00000291532 NM_032404.2 392 gGt/gAt 0 +TNFAIP1 UCSF GRCh37 17 26669339 26669339 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 42 34 80 0 ENST00000226225.2:c.585C>T p.Gly195= p.G195= ENST00000226225 NM_021137.4 195 ggC/ggT 0 +TNFAIP8L3 UCSF GRCh37 15 51350625 51350625 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 33 80 0 ENST00000327536.5:c.332G>A p.Ser111Asn p.S111N ENST00000327536 NM_207381.2 111 aGt/aAt 0 +TNFRSF10B UCSF GRCh37 8 22926275 22926275 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 14 22 0 ENST00000276431.4:c.133G>A p.Val45Ile p.V45I ENST00000276431 NM_147187.2 45 Gtc/Atc 0 +TNFRSF13C UCSF GRCh37 22 42322114 42322114 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 13 30 0 ENST00000291232.3:c.358G>A p.Asp120Asn p.D120N ENST00000291232 NM_052945.3 120 Gac/Aac 0 +TNFRSF4 UCSF GRCh37 1 1147450 1147450 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 9 18 0 ENST00000379236.3:c.506G>A p.Arg169Lys p.R169K ENST00000379236 NM_003327.3 169 aGg/aAg 0 +TNK1 UCSF GRCh37 17 7290413 7290413 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 31 49 0 ENST00000576812.1:c.1352C>T p.Thr451Ile p.T451I ENST00000576812 NM_001251902.1 451 aCc/aTc 0 +TNK2 UCSF GRCh37 3 195608963 195608963 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 48 120 0 ENST00000333602.6:c.846C>T p.Asp282= p.D282= ENST00000333602 NM_005781.4 282 gaC/gaT 0 +TNNI1 UCSF GRCh37 1 201383683 201383683 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 16 33 0 ENST00000336092.4:c.152C>T p.Thr51Met p.T51M ENST00000336092 51 aCg/aTg 0 +TNNI3 UCSF GRCh37 19 55665468 55665468 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 69 129 0 ENST00000344887.5:c.479G>A p.Gly160Glu p.G160E ENST00000344887 NM_000363.4 160 gGg/gAg 0 +TNRC18 UCSF GRCh37 7 5353477 5353477 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 28 52 0 ENST00000430969.1:c.7045G>A p.Glu2349Lys p.E2349K ENST00000430969 NM_001080495.2 2349 Gag/Aag 0 +TNRC18 UCSF GRCh37 7 5410939 5410939 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 12 26 0 ENST00000430969.1:c.3286C>T p.Pro1096Ser p.P1096S ENST00000430969 NM_001080495.2 1096 Cct/Tct 0 +TNXB UCSF GRCh37 6 32065707 32065707 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 53 105 0 ENST00000375244.3:c.269G>A p.Gly90Asp p.G90D ENST00000375244 90 gGc/gAc 0 +TOB1 UCSF GRCh37 17 48941018 48941018 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 71 171 0 ENST00000268957.3:c.361G>A p.Gly121Arg p.G121R ENST00000268957 NM_001243877.1 121 Gga/Aga 0 +TOM1 UCSF GRCh37 22 35713897 35713897 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 62 133 0 ENST00000449058.2:c.80G>A p.Ser27Asn p.S27N ENST00000449058 NM_005488.2 27 aGc/aAc 0 +TONSL UCSF GRCh37 8 145659615 145659615 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 9 23 0 ENST00000409379.3:c.3133C>T p.Leu1045Phe p.L1045F ENST00000409379 NM_013432.4 1045 Ctc/Ttc 0 +TOP1 UCSF GRCh37 20 39741529 39741529 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 55 126 0 ENST00000361337.2:c.1416C>T p.Val472= p.V472= ENST00000361337 NM_003286.2 472 gtC/gtT 0 +TOP2A UCSF GRCh37 17 38563110 38563110 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 128 231 0 ENST00000423485.1:c.1711G>A p.Glu571Lys p.E571K ENST00000423485 NM_001067.3 571 Gag/Aag 0 +TOP2B UCSF GRCh37 3 25670612 25670612 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 179 115 250 0 ENST00000264331.4:c.1714G>A p.Gly572Ser p.G572S ENST00000264331 572 Ggc/Agc 0 +TOR1AIP2 UCSF GRCh37 1 179820072 179820072 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 79 200 0 ENST00000367612.3:c.461C>T p.Pro154Leu p.P154L ENST00000367612 NM_145034.4 154 cCt/cTt 0 +TOR1B UCSF GRCh37 9 132571237 132571237 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 67 161 0 ENST00000259339.2:c.695G>A p.Gly232Glu p.G232E ENST00000259339 NM_014506.1 232 gGa/gAa 0 +TOR2A UCSF GRCh37 9 130495599 130495599 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 57 133 0 ENST00000373284.5:c.593+65C>T *198* ENST00000373284 NM_001085347.2 0 +TP53 UCSF GRCh37 17 7578242 7578242 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 69 41 111 0 ENST00000269305.4:c.607G>A p.Val203Met p.V203M ENST00000269305 NM_001126112.2 203 Gtg/Atg 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 18 61 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TPR UCSF GRCh37 1 186287932 186287932 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 74 190 0 ENST00000367478.4:c.6597C>T p.Phe2199= p.F2199= ENST00000367478 NM_003292.2 2199 ttC/ttT 0 +TRAF3IP1 UCSF GRCh37 2 239242654 239242654 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 31 69 0 ENST00000373327.4:c.1041G>A p.Arg347= p.R347= ENST00000373327 NM_015650.3 347 cgG/cgA 0 +TRAF3IP3 UCSF GRCh37 1 209936207 209936207 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 71 196 0 ENST00000367024.1:c.543G>A p.Gln181= p.Q181= ENST00000367024 181 caG/caA 0 +TRAFD1 UCSF GRCh37 12 112585941 112585941 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 60 112 0 ENST00000257604.5:c.991G>A p.Val331Met p.V331M ENST00000257604 NM_001143906.1 331 Gtg/Atg 0 +TRANK1 UCSF GRCh37 3 36896976 36896976 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 198 148 338 0 ENST00000429976.2:c.4105G>A p.Val1369Ile p.V1369I ENST00000429976 1369 Gtt/Att 0 +TRAPPC10 UCSF GRCh37 21 45506703 45506703 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 74 156 0 ENST00000291574.4:c.2401C>T p.Pro801Ser p.P801S ENST00000291574 NM_003274.4 801 Cct/Tct 0 +TREX1 UCSF GRCh37 3 48508814 48508814 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 81 157 0 ENST00000422277.2:c.925C>T p.Leu309= p.L309= ENST00000422277 NM_016381.4 309 Ctg/Ttg 0 +TRIM29 UCSF GRCh37 11 120008683 120008683 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 23 70 0 ENST00000341846.5:c.57C>T p.Ala19= p.A19= ENST00000341846 NM_012101.3 19 gcC/gcT 0 +TRIM33 UCSF GRCh37 1 114940462 114940462 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 167 135 246 0 ENST00000358465.2:c.3192G>A p.Gln1064= p.Q1064= ENST00000358465 NM_015906.3 1064 caG/caA 0 +TRIM43B UCSF GRCh37 2 96147415 96147415 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 51 162 0 ENST00000454263.2:n.565G>A *189* ENST00000454263 0 +TRIM45 UCSF GRCh37 1 117663495 117663495 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 66 112 0 ENST00000256649.4:c.329C>T p.Ala110Val p.A110V ENST00000256649 NM_025188.3 110 gCt/gTt 0 +TRIM47 UCSF GRCh37 17 73872525 73872525 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 15 40 0 ENST00000254816.2:c.820G>A p.Ala274Thr p.A274T ENST00000254816 NM_033452.2 274 Gct/Act 0 +TRIM50 UCSF GRCh37 7 72738554 72738554 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 58 123 0 ENST00000333149.2:c.232C>T p.Leu78= p.L78= ENST00000333149 NM_001281450.1 78 Ctg/Ttg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 159 107 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Rec Untested WXS Illumina HiSeq 147 106 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +TRIM55 UCSF GRCh37 8 67086798 67086798 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 179 112 235 0 ENST00000315962.4:c.1617C>T p.Ser539= p.S539= ENST00000315962 NM_184085.1 539 tcC/tcT 0 +TRIM71 UCSF GRCh37 3 32933098 32933098 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 81 145 0 ENST00000383763.5:c.2402C>T p.Ala801Val p.A801V ENST00000383763 NM_001039111.1 801 gCt/gTt 0 +TRIM71 UCSF GRCh37 3 32932469 32932469 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 45 95 0 ENST00000383763.5:c.1773C>T p.Leu591= p.L591= ENST00000383763 NM_001039111.1 591 ctC/ctT 0 +TRIM77P UCSF GRCh37 11 89443679 89443679 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 90 211 0 ENST00000398290.3:c.213G>A p.Glu71= p.E71= ENST00000398290 NM_001146162.1 71 gaG/gaA 0 +TRIM9 UCSF GRCh37 14 51446261 51446261 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 166 105 231 0 ENST00000298355.3:c.1914G>A p.Glu638= p.E638= ENST00000298355 NM_015163.5 638 gaG/gaA 0 +TRIM9 UCSF GRCh37 14 51448685 51448685 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 84 144 0 ENST00000298355.3:c.1740C>T p.Tyr580= p.Y580= ENST00000298355 NM_015163.5 580 taC/taT 0 +TRIO UCSF GRCh37 5 14368834 14368834 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 81 162 0 ENST00000344204.4:c.2892G>A p.Ala964= p.A964= ENST00000344204 NM_007118.2 964 gcG/gcA 0 +TRIP11 UCSF GRCh37 14 92482083 92482083 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 66 154 0 ENST00000267622.4:c.780C>T p.Asp260= p.D260= ENST00000267622 NM_004239.3 260 gaC/gaT 0 +TRMT5 UCSF GRCh37 14 61441857 61441857 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0014 P18_Rec Untested WXS Illumina HiSeq 71 49 98 0 ENST00000261249.6:c.1500C>T p.Asp500= p.D500= ENST00000261249 NM_020810.2 500 gaC/gaT 0 +TRPA1 UCSF GRCh37 8 72968057 72968057 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 64 116 0 ENST00000262209.4:c.1228G>A p.Asp410Asn p.D410N ENST00000262209 NM_007332.2 410 Gac/Aac 0 +TRPC4AP UCSF GRCh37 20 33600840 33600840 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 74 184 0 ENST00000252015.2:c.1380G>A p.Arg460= p.R460= ENST00000252015 460 agG/agA 0 +TRPM2 UCSF GRCh37 21 45859007 45859007 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 36 72 0 ENST00000300482.5:c.4225G>A p.Glu1409Lys p.E1409K ENST00000300482 1409 Gag/Aag 0 +TRPM5 UCSF GRCh37 11 2441483 2441483 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 40 77 0 ENST00000155858.6:c.618G>A p.Lys206= p.K206= ENST00000155858 NM_014555.3 206 aaG/aaA 0 +TRPM6 UCSF GRCh37 9 77397347 77397347 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 85 176 0 ENST00000360774.1:c.3140C>T p.Pro1047Leu p.P1047L ENST00000360774 NM_017662.4 1047 cCa/cTa 0 +TRPS1 UCSF GRCh37 8 116616617 116616617 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 161 109 235 0 ENST00000220888.5:c.1540G>A p.Gly514Arg p.G514R ENST00000220888 514 Gga/Aga 0 +TRPV2 UCSF GRCh37 17 16330800 16330800 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 96 64 113 0 ENST00000338560.7:c.1289C>T p.Ser430Phe p.S430F ENST00000338560 NM_016113.4 430 tCc/tTc 0 +TRPV2 UCSF GRCh37 17 16330170 16330170 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 59 127 0 ENST00000338560.7:c.1230C>T p.Tyr410= p.Y410= ENST00000338560 NM_016113.4 410 taC/taT 0 +TRRAP UCSF GRCh37 7 98581887 98581887 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 368 118 397 0 ENST00000359863.4:c.9206C>T p.Thr3069Ile p.T3069I ENST00000359863 NM_001244580.1 3069 aCt/aTt 0 +TSC1 UCSF GRCh37 9 135772893 135772893 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 182 125 287 0 ENST00000298552.3:c.2730G>A p.Leu910= p.L910= ENST00000298552 NM_001162426.1 910 ttG/ttA 0 +TSEN2 UCSF GRCh37 3 12544891 12544891 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 88 179 0 ENST00000284995.6:c.439G>A p.Ala147Thr p.A147T ENST00000284995 NM_025265.3 147 Gct/Act 0 +TSHZ3 UCSF GRCh37 19 31768396 31768396 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 48 109 0 ENST00000240587.4:c.2303C>T p.Pro768Leu p.P768L ENST00000240587 NM_020856.2 768 cCc/cTc 0 +TSN UCSF GRCh37 2 122519079 122519079 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 154 307 0 ENST00000389682.3:c.352G>A p.Ala118Thr p.A118T ENST00000389682 NM_004622.2 118 Gca/Aca 0 +TSN UCSF GRCh37 2 122514836 122514836 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 50 122 0 ENST00000389682.3:c.87G>A p.Gln29= p.Q29= ENST00000389682 NM_004622.2 29 caG/caA 0 +TSPAN32 UCSF GRCh37 11 2325364 2325364 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 19 31 0 ENST00000182290.4:c.209G>A p.Gly70Asp p.G70D ENST00000182290 NM_139022.2 70 gGc/gAc 0 +TSPAN5 UCSF GRCh37 4 99579356 99579356 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 70 171 0 ENST00000305798.3:c.22G>A p.Gly8Ser p.G8S ENST00000305798 NM_005723.3 8 Ggt/Agt 0 +TSPYL2 UCSF GRCh37 X 53112481 53112481 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 47 54 0 ENST00000375442.4:c.801C>T p.Val267= p.V267= ENST00000375442 NM_022117.3 267 gtC/gtT 0 +TSSK4 UCSF GRCh37 14 24676709 24676709 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 44 119 0 ENST00000287913.6:c.798G>A p.Glu266= p.E266= ENST00000287913 266 gaG/gaA 0 +TTBK1 UCSF GRCh37 6 43250801 43250801 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 18 0 ENST00000259750.4:c.2323G>A p.Ala775Thr p.A775T ENST00000259750 NM_032538.1 775 Gca/Aca 0 +TTC38 UCSF GRCh37 22 46668245 46668245 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 51 133 0 ENST00000381031.3:c.125C>T p.Thr42Ile p.T42I ENST00000381031 NM_017931.2 42 aCc/aTc 0 +TTC38 UCSF GRCh37 22 46669910 46669910 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 66 129 0 ENST00000381031.3:c.309G>A p.Gln103= p.Q103= ENST00000381031 NM_017931.2 103 caG/caA 0 +TTC39A UCSF GRCh37 1 51760071 51760071 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 76 109 0 ENST00000447632.2:c.1366C>T p.Pro456Ser p.P456S ENST00000447632 456 Cct/Tct 0 +TTC39C UCSF GRCh37 18 21660666 21660666 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 86 67 149 0 ENST00000317571.3:c.578C>T p.Thr193Ile p.T193I ENST00000317571 NM_001135993.1 193 aCt/aTt 0 +TTC7B UCSF GRCh37 14 91142910 91142910 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 91 207 0 ENST00000328459.6:c.1109C>T p.Thr370Ile p.T370I ENST00000328459 NM_001010854.1 370 aCc/aTc 0 +TTF2 UCSF GRCh37 1 117618096 117618096 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 99 65 197 0 ENST00000369466.4:c.890A>G p.Asp297Gly p.D297G ENST00000369466 NM_003594.3 297 gAt/gGt 0 +TTI1 UCSF GRCh37 20 36641885 36641885 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 103 235 0 ENST00000373447.3:c.334C>T p.Pro112Ser p.P112S ENST00000373447 112 Cct/Tct 0 +TTLL2 UCSF GRCh37 6 167755101 167755101 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 87 65 148 0 ENST00000239587.5:c.1713G>A p.Arg571= p.R571= ENST00000239587 NM_031949.4 571 agG/agA 0 +TTLL4 UCSF GRCh37 2 219603311 219603311 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 105 184 0 ENST00000258398.4:c.912G>A p.Trp304Ter p.W304* ENST00000258398 304 tgG/tgA 0 +TTLL5 UCSF GRCh37 14 76211907 76211907 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 51 125 0 ENST00000298832.9:c.1470G>A p.Glu490= p.E490= ENST00000298832 NM_015072.4 490 gaG/gaA 0 +TTN UCSF GRCh37 2 179429104 179429104 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 160 107 256 0 ENST00000591111.1:c.76832G>A p.Gly25611Glu p.G25611E ENST00000591111 25611 gGa/gAa 0 +TTN UCSF GRCh37 2 179425139 179425139 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 214 189 343 0 ENST00000591111.1:c.80797C>T p.Pro26933Ser p.P26933S ENST00000591111 26933 Ccc/Tcc 0 +TTN UCSF GRCh37 2 179500188 179500188 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 163 95 222 0 ENST00000591111.1:c.36940C>T p.Pro12314Ser p.P12314S ENST00000591111 12314 Cct/Tct 0 +TTN UCSF GRCh37 2 179642652 179642652 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 47 108 0 ENST00000591111.1:c.4259C>T p.Ala1420Val p.A1420V ENST00000591111 1420 gCa/gTa 0 +TTN UCSF GRCh37 2 179429433 179429433 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 129 106 194 0 ENST00000591111.1:c.76503G>A p.Glu25501= p.E25501= ENST00000591111 25501 gaG/gaA 0 +TUBAL3 UCSF GRCh37 10 5436157 5436157 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 70 144 0 ENST00000380419.3:c.664C>T p.Arg222Cys p.R222C ENST00000380419 NM_024803.2 222 Cgt/Tgt 0 +TUBAL3 UCSF GRCh37 10 5435827 5435827 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.00094 P18_Rec Untested WXS Illumina HiSeq 146 96 153 0 ENST00000380419.3:c.994C>T p.Pro332Ser p.P332S ENST00000380419 NM_024803.2 332 Ccc/Tcc 0 +TUBB UCSF GRCh37 6 30691620 30691620 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 129 102 220 0 ENST00000327892.8:c.781C>T p.Pro261Ser p.P261S ENST00000327892 NM_178014.2 261 Cca/Tca 0 +TUBB6 UCSF GRCh37 18 12308752 12308752 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 54 108 0 ENST00000317702.5:c.124C>T p.Leu42= p.L42= ENST00000317702 42 Ctg/Ttg 0 +TUFM UCSF GRCh37 16 28856684 28856684 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 211 84 204 0 ENST00000313511.3:c.365C>T p.Ala122Val p.A122V ENST00000313511 NM_003321.4 122 gCc/gTc 0 +TWF2 UCSF GRCh37 3 52269091 52269091 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 37 67 0 ENST00000305533.5:c.57G>A p.Lys19= p.K19= ENST00000305533 NM_007284.3 19 aaG/aaA 0 +TXLNG UCSF GRCh37 X 16859664 16859664 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 75 79 0 ENST00000380122.5:c.1362C>T p.Val454= p.V454= ENST00000380122 NM_018360.2 454 gtC/gtT 0 +TXNL4B UCSF GRCh37 16 72124636 72124636 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 101 198 0 ENST00000268483.3:c.13C>T p.Leu5= p.L5= ENST00000268483 NM_017853.2 5 Ctg/Ttg 0 +TXNRD1 UCSF GRCh37 12 104712817 104712817 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 191 155 290 0 ENST00000525566.1:c.857G>A p.Gly286Asp p.G286D ENST00000525566 NM_001093771.2 286 gGt/gAt 0 +TYK2 UCSF GRCh37 19 10475430 10475430 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 57 114 0 ENST00000264818.6:c.1227C>T p.Ser409= p.S409= ENST00000264818 409 tcC/tcT 0 +TYW1B UCSF GRCh37 7 72267497 72267497 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 191 144 289 0 ENST00000438904.2:c.764G>A p.Gly255Asp p.G255D ENST00000438904 255 gGt/gAt 0 +UBA6 UCSF GRCh37 4 68530983 68530983 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 59 179 0 ENST00000322244.5:c.821G>A p.Gly274Asp p.G274D ENST00000322244 NM_018227.5 274 gGt/gAt 0 +UBE2F UCSF GRCh37 2 238881803 238881803 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 152 100 234 0 ENST00000272930.4:c.54G>A p.Arg18= p.R18= ENST00000272930 NM_001278308.1 18 cgG/cgA 0 +UBE2O UCSF GRCh37 17 74397137 74397137 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 36 77 0 ENST00000319380.7:c.849G>A p.Lys283= p.K283= ENST00000319380 NM_022066.3 283 aaG/aaA 0 +UBE4B UCSF GRCh37 1 10186901 10186901 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 68 173 0 ENST00000343090.6:c.1604C>T p.Ser535Phe p.S535F ENST00000343090 NM_001105562.2 535 tCc/tTc 0 +UBQLN1 UCSF GRCh37 9 86294846 86294846 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 185 137 280 0 ENST00000376395.4:c.555G>A p.Met185Ile p.M185I ENST00000376395 NM_053067.2 185 atG/atA 0 +UBR3 UCSF GRCh37 2 170734087 170734087 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 77 173 0 ENST00000272793.5:c.928G>A p.Asp310Asn p.D310N ENST00000272793 310 Gat/Aat 0 +UBR3 UCSF GRCh37 2 170912076 170912076 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 60 102 0 ENST00000272793.5:c.4767C>T p.His1589= p.H1589= ENST00000272793 1589 caC/caT 0 +UBR4 UCSF GRCh37 1 19453150 19453150 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 42 86 0 ENST00000375254.3:c.9229-1G>A p.X3077_splice ENST00000375254 NM_020765.2 0 +UBR5 UCSF GRCh37 8 103283366 103283366 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 70 125 0 ENST00000520539.1:c.7081G>A p.Asp2361Asn p.D2361N ENST00000520539 NM_015902.5 2361 Gat/Aat 0 +UBTF UCSF GRCh37 17 42288315 42288315 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 25 74 0 ENST00000302904.4:c.1204G>A p.Gly402Ser p.G402S ENST00000302904 402 Ggc/Agc 0 +UCN3 UCSF GRCh37 10 5415867 5415867 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 35 43 0 ENST00000380433.3:c.184C>T p.Leu62= p.L62= ENST00000380433 NM_053049.2 62 Ctg/Ttg 0 +UGT2A3 UCSF GRCh37 4 69817062 69817062 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 63 170 0 ENST00000251566.4:c.417G>A p.Gln139= p.Q139= ENST00000251566 NM_024743.3 139 caG/caA 0 +UGT2B7 UCSF GRCh37 4 69964261 69964261 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 173 111 283 0 ENST00000305231.7:c.725G>A p.Arg242Lys p.R242K ENST00000305231 NM_001074.2 242 aGa/aAa 0 +UGT3A1 UCSF GRCh37 5 35965937 35965937 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 63 166 0 ENST00000274278.3:c.394G>A p.Asp132Asn p.D132N ENST00000274278 NM_152404.3 132 Gat/Aat 0 +UGT3A2 UCSF GRCh37 5 36035916 36035916 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 39 102 1 ENST00000282507.3:c.1456C>T p.Leu486Phe p.L486F ENST00000282507 NM_174914.3 486 Ctc/Ttc 0 +UGT3A2 UCSF GRCh37 5 36038081 36038081 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 64 165 0 ENST00000282507.3:c.1113G>A p.Gly371= p.G371= ENST00000282507 NM_174914.3 371 ggG/ggA 0 +UHRF1BP1L UCSF GRCh37 12 100453025 100453025 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 92 180 0 ENST00000279907.7:c.2030C>T p.Thr677Ile p.T677I ENST00000279907 NM_015054.1 677 aCt/aTt 0 +ULK2 UCSF GRCh37 17 19700973 19700973 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 39 72 0 ENST00000361658.2:c.1545G>A p.Gln515= p.Q515= ENST00000361658 NM_001142610.1 515 caG/caA 0 +UNC45A UCSF GRCh37 15 91486148 91486148 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 127 89 221 0 ENST00000418476.2:c.863C>T p.Ala288Val p.A288V ENST00000418476 NM_018671.3 288 gCc/gTc 0 +UNC5C UCSF GRCh37 4 96104058 96104058 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 90 199 0 ENST00000453304.1:c.2441C>T p.Thr814Ile p.T814I ENST00000453304 NM_003728.3 814 aCc/aTc 0 +UPF2 UCSF GRCh37 10 12021094 12021094 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 241 79 195 0 ENST00000356352.2:c.1915G>A p.Asp639Asn p.D639N ENST00000356352 639 Gat/Aat 0 +UPF2 UCSF GRCh37 10 12077080 12077080 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 282 166 267 0 ENST00000356352.2:c.343G>A p.Glu115Lys p.E115K ENST00000356352 115 Gaa/Aaa 0 +URB1 UCSF GRCh37 21 33755740 33755740 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 31 71 0 ENST00000382751.3:c.558G>A p.Arg186= p.R186= ENST00000382751 NM_014825.2 186 agG/agA 0 +URGCP UCSF GRCh37 7 43917741 43917741 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 105 213 0 ENST00000453200.1:c.1321G>A p.Ala441Thr p.A441T ENST00000453200 441 Gca/Aca 0 +USH2A UCSF GRCh37 1 216420210 216420210 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 129 223 0 ENST00000307340.3:c.2526C>T p.Phe842= p.F842= ENST00000307340 NM_206933.2 842 ttC/ttT 0 +USHBP1 UCSF GRCh37 19 17370229 17370229 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 68 151 0 ENST00000252597.3:c.915G>A p.Glu305= p.E305= ENST00000252597 NM_031941.3 305 gaG/gaA 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 27 106 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +USP19 UCSF GRCh37 3 49154746 49154746 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 27 78 0 ENST00000398888.2:c.606+124G>A *202* ENST00000398888 NM_006677.2 0 +USP20 UCSF GRCh37 9 132635984 132635984 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 50 128 0 ENST00000315480.4:c.1701G>A p.Arg567= p.R567= ENST00000315480 567 cgG/cgA 0 +USP32 UCSF GRCh37 17 58303402 58303402 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 91 197 0 ENST00000300896.4:c.1430G>A p.Ser477Asn p.S477N ENST00000300896 NM_032582.3 477 aGc/aAc 0 +USP34 UCSF GRCh37 2 61597500 61597500 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 25 244 0 ENST00000398571.2:c.1207C>T p.Arg403Ter p.R403* ENST00000398571 NM_014709.3 403 Cga/Tga 0 +USP36 UCSF GRCh37 17 76816091 76816091 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 63 192 0 ENST00000542802.3:c.832G>A p.Ala278Thr p.A278T ENST00000542802 278 Gct/Act 0 +USP42 UCSF GRCh37 7 6196395 6196395 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 34 148 0 ENST00000306177.5:c.3652G>A p.Asp1218Asn p.D1218N ENST00000306177 NM_032172.2 1218 Gac/Aac 0 +USP43 UCSF GRCh37 17 9580186 9580186 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 56 109 0 ENST00000285199.7:c.957C>T p.Val319= p.V319= ENST00000285199 NM_001267576.1 319 gtC/gtT 0 +USP43 UCSF GRCh37 17 9631548 9631548 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 52 162 0 ENST00000285199.7:c.2613C>T p.Ala871= p.A871= ENST00000285199 NM_001267576.1 871 gcC/gcT 0 +USP44 UCSF GRCh37 12 95926690 95926690 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 68 182 0 ENST00000258499.3:c.1343C>T p.Ala448Val p.A448V ENST00000258499 NM_032147.3 448 gCt/gTt 0 +USP48 UCSF GRCh37 1 22083161 22083161 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 102 244 0 ENST00000308271.9:c.290C>T p.Thr97Ile p.T97I ENST00000308271 NM_032236.5 97 aCt/aTt 0 +USP51 UCSF GRCh37 X 55513774 55513774 + synonymous_variant Silent SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 8 51 69 0 ENST00000500968.3:c.1599T>G p.Ala533= p.A533= ENST00000500968 NM_201286.3 533 gcT/gcG 0 +USP7 UCSF GRCh37 16 8997143 8997143 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 49 139 0 ENST00000344836.4:c.1821G>A p.Gln607= p.Q607= ENST00000344836 NM_003470.2 607 caG/caA 0 +USP7 UCSF GRCh37 16 9009190 9009190 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 227 92 203 0 ENST00000344836.4:c.999G>A p.Gln333= p.Q333= ENST00000344836 NM_003470.2 333 caG/caA 0 +USPL1 UCSF GRCh37 13 31232629 31232629 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 55 189 0 ENST00000255304.4:c.2415C>T p.Asn805= p.N805= ENST00000255304 NM_005800.4 805 aaC/aaT 0 +VAMP1 UCSF GRCh37 12 6575007 6575007 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 69 124 0 ENST00000396308.3:c.288+1G>A p.X96_splice ENST00000396308 NM_199245.1 0 +VAMP4 UCSF GRCh37 1 171697711 171697711 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 27 21 49 0 ENST00000236192.7:c.67-1G>A p.X23_splice ENST00000236192 NM_003762.4 0 +VANGL1 UCSF GRCh37 1 116206884 116206884 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 27 19 52 0 ENST00000310260.3:c.807C>T p.His269= p.H269= ENST00000310260 NM_001172412.1 269 caC/caT 0 +VARS UCSF GRCh37 6 31760855 31760855 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 34 60 0 ENST00000375663.3:c.430G>A p.Glu144Lys p.E144K ENST00000375663 NM_006295.2 144 Gag/Aag 0 +VARS2 UCSF GRCh37 6 30882677 30882677 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 64 134 0 ENST00000321897.5:c.64C>T p.Leu22Phe p.L22F ENST00000321897 22 Ctc/Ttc 0 +VARS2 UCSF GRCh37 6 30892185 30892185 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 25 62 0 ENST00000321897.5:c.2521G>A p.Val841Ile p.V841I ENST00000321897 841 Gtc/Atc 0 +VAT1 UCSF GRCh37 17 41168536 41168536 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 29 70 0 ENST00000355653.3:c.886C>T p.Arg296Trp p.R296W ENST00000355653 NM_006373.3 296 Cgg/Tgg 0 +VAV2 UCSF GRCh37 9 136857324 136857324 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 9 15 0 ENST00000371850.3:c.77C>T p.Pro26Leu p.P26L ENST00000371850 NM_001134398.1 26 cCc/cTc 0 +VAX2 UCSF GRCh37 2 71160000 71160000 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 22 67 0 ENST00000234392.2:c.539C>T p.Ser180Phe p.S180F ENST00000234392 NM_012476.2 180 tCc/tTc 0 +VEGFC UCSF GRCh37 4 177649081 177649081 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 69 150 0 ENST00000280193.2:c.403G>A p.Glu135Lys p.E135K ENST00000280193 NM_005429.3 135 Gag/Aag 0 +VGLL3 UCSF GRCh37 3 87039824 87039824 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 10 44 0 ENST00000398399.2:c.70G>A p.Ala24Thr p.A24T ENST00000398399 NM_016206.2 24 Gca/Aca 0 +VIL1 UCSF GRCh37 2 219295554 219295554 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 34 103 0 ENST00000248444.5:c.1055C>T p.Ser352Phe p.S352F ENST00000248444 NM_007127.2 352 tCc/tTc 0 +VIL1 UCSF GRCh37 2 219301967 219301967 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 73 145 0 ENST00000248444.5:c.2092G>A p.Val698Met p.V698M ENST00000248444 NM_007127.2 698 Gtg/Atg 0 +VIPR2 UCSF GRCh37 7 158824555 158824555 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 43 113 0 ENST00000262178.2:c.1107G>A p.Leu369= p.L369= ENST00000262178 NM_003382.4 369 ctG/ctA 0 +VIT UCSF GRCh37 2 37041492 37041492 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 64 147 0 ENST00000389975.3:c.2025G>A p.Gln675= p.Q675= ENST00000389975 NM_001177970.1 675 caG/caA 0 +VOPP1 UCSF GRCh37 7 55560094 55560094 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 13 41 0 ENST00000285279.5:c.209G>A p.Gly70Asp p.G70D ENST00000285279 NM_030796.3 70 gGc/gAc 0 +VPRBP UCSF GRCh37 3 51475733 51475733 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 211 150 346 0 ENST00000504652.1:c.694G>A p.Glu232Lys p.E232K ENST00000504652 232 Gaa/Aaa 0 +VPS13D UCSF GRCh37 1 12429692 12429692 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 99 228 0 ENST00000358136.3:c.10743C>T p.Phe3581= p.F3581= ENST00000358136 NM_015378.2 3581 ttC/ttT 0 +VPS13D UCSF GRCh37 1 12557575 12557575 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 66 110 0 ENST00000358136.3:c.12684G>A p.Arg4228= p.R4228= ENST00000358136 NM_015378.2 4228 cgG/cgA 0 +VPS33A UCSF GRCh37 12 122726966 122726966 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 94 209 0 ENST00000267199.4:c.1059C>T p.Asn353= p.N353= ENST00000267199 NM_022916.4 353 aaC/aaT 0 +VPS33B UCSF GRCh37 15 91543182 91543182 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 102 205 0 ENST00000333371.3:c.1605G>A p.Gln535= p.Q535= ENST00000333371 NM_018668.3 535 caG/caA 0 +VPS39 UCSF GRCh37 15 42454583 42454583 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 51 116 0 ENST00000348544.4:c.2305C>T p.Gln769Ter p.Q769* ENST00000348544 769 Cag/Tag 0 +VPS39 UCSF GRCh37 15 42453939 42453939 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 175 109 221 0 ENST00000348544.4:c.2526G>A p.Val842= p.V842= ENST00000348544 842 gtG/gtA 0 +VPS53 UCSF GRCh37 17 465893 465893 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 65 118 0 ENST00000571805.1:c.1406C>T p.Pro469Leu p.P469L ENST00000571805 469 cCc/cTc 0 +VPS54 UCSF GRCh37 2 64161058 64161058 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 56 117 0 ENST00000272322.4:c.1488G>A p.Lys496= p.K496= ENST00000272322 496 aaG/aaA 0 +VSIG10L UCSF GRCh37 19 51840535 51840535 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 19 51 0 ENST00000335624.4:c.2262G>A p.Gly754= p.G754= ENST00000335624 NM_001163922.1 754 ggG/ggA 0 +VSTM4 UCSF GRCh37 10 50315883 50315883 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 46 142 0 ENST00000332853.4:c.213G>A p.Gln71= p.Q71= ENST00000332853 NM_001031746.3 71 caG/caA 0 +VTN UCSF GRCh37 17 26694933 26694933 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 25 62 0 ENST00000226218.4:c.1127G>A p.Arg376His p.R376H ENST00000226218 NM_000638.3 376 cGc/cAc 0 +VWA3B UCSF GRCh37 2 98846658 98846658 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 61 118 0 ENST00000477737.1:c.2296G>A p.Val766Ile p.V766I ENST00000477737 NM_144992.4 766 Gtc/Atc 0 +VWA5B2 UCSF GRCh37 3 183958847 183958847 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 16 35 0 ENST00000426955.2:c.2914C>T p.His972Tyr p.H972Y ENST00000426955 NM_138345.1 972 Cac/Tac 0 +VWDE UCSF GRCh37 7 12376886 12376886 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 45 122 0 ENST00000275358.3:c.4379C>T p.Pro1460Leu p.P1460L ENST00000275358 NM_001135924.1 1460 cCt/cTt 0 +WAPAL UCSF GRCh37 10 88211755 88211755 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 79 165 0 ENST00000298767.5:c.3083G>A p.Gly1028Glu p.G1028E ENST00000298767 NM_015045.2 1028 gGa/gAa 0 +WAPAL UCSF GRCh37 10 88233649 88233649 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 90 212 0 ENST00000298767.5:c.1726C>T p.Pro576Ser p.P576S ENST00000298767 NM_015045.2 576 Cct/Tct 0 +WBP4 UCSF GRCh37 13 41639178 41639178 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 49 134 0 ENST00000379487.3:c.102G>A p.Lys34= p.K34= ENST00000379487 NM_007187.3 34 aaG/aaA 0 +WDFY3 UCSF GRCh37 4 85771060 85771060 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 154 100 247 0 ENST00000295888.4:c.299C>T p.Ser100Phe p.S100F ENST00000295888 NM_014991.4 100 tCc/tTc 0 +WDFY3 UCSF GRCh37 4 85599335 85599335 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 72 177 0 ENST00000295888.4:c.10245C>T p.Ala3415= p.A3415= ENST00000295888 NM_014991.4 3415 gcC/gcT 0 +WDFY3 UCSF GRCh37 4 85605246 85605246 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 50 143 0 ENST00000295888.4:c.9576C>T p.Ile3192= p.I3192= ENST00000295888 NM_014991.4 3192 atC/atT 0 +WDFY4 UCSF GRCh37 10 50040716 50040716 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 112 108 168 0 ENST00000325239.5:c.6625C>T p.Pro2209Ser p.P2209S ENST00000325239 NM_020945.1 2209 Ccc/Tcc 0 +WDFY4 UCSF GRCh37 10 49951044 49951044 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 21 51 0 ENST00000325239.5:c.1910G>A p.Gly637Asp p.G637D ENST00000325239 NM_020945.1 637 gGt/gAt 0 +WDR11 UCSF GRCh37 10 122645451 122645451 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 68 144 0 ENST00000263461.6:c.1973+1G>A p.X658_splice ENST00000263461 NM_018117.11 0 +WDR36 UCSF GRCh37 5 110441832 110441832 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 80 162 0 ENST00000506538.2:c.1338G>A p.Lys446= p.K446= ENST00000506538 NM_139281.2 446 aaG/aaA 0 +WDR47 UCSF GRCh37 1 109533922 109533922 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 88 193 1 ENST00000369962.3:c.1721C>T p.Pro574Leu p.P574L ENST00000369962 574 cCt/cTt 0 +WDR48 UCSF GRCh37 3 39116230 39116230 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 52 111 0 ENST00000302313.5:c.686G>A p.Ser229Asn p.S229N ENST00000302313 NM_020839.2 229 aGt/aAt 0 +WDR54 UCSF GRCh37 2 74650480 74650480 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 111 187 0 ENST00000348227.4:c.320G>A p.Trp107Ter p.W107* ENST00000348227 NM_032118.2 107 tGg/tAg 0 +WDR60 UCSF GRCh37 7 158662547 158662547 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 68 186 0 ENST00000407559.3:c.17G>A p.Arg6Lys p.R6K ENST00000407559 NM_018051.4 6 aGa/aAa 0 +WDR61 UCSF GRCh37 15 78585531 78585531 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 80 184 0 ENST00000267973.2:c.124G>A p.Asp42Asn p.D42N ENST00000267973 42 Gac/Aac 0 +WDR63 UCSF GRCh37 1 85592310 85592310 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 75 139 0 ENST00000294664.6:c.2229G>A p.Trp743Ter p.W743* ENST00000294664 NM_145172.3 743 tgG/tgA 0 +WDR69 UCSF GRCh37 2 228786134 228786134 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 96 182 0 ENST00000309931.2:c.1070G>A p.Gly357Glu p.G357E ENST00000309931 NM_178821.1 357 gGg/gAg 0 +WDR76 UCSF GRCh37 15 44158475 44158475 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 122 212 0 ENST00000263795.6:c.1766G>A p.Gly589Glu p.G589E ENST00000263795 NM_001167941.1 589 gGa/gAa 0 +WDR82 UCSF GRCh37 3 52293841 52293841 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 201 139 258 0 ENST00000296490.3:c.591G>A p.Trp197Ter p.W197* ENST00000296490 NM_025222.3 197 tgG/tgA 0 +WDR87 UCSF GRCh37 19 38377607 38377607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 104 241 0 ENST00000303868.5:c.6587G>A p.Arg2196Lys p.R2196K ENST00000303868 NM_031951.3 2196 aGg/aAg 0 +WDR87 UCSF GRCh37 19 38385526 38385526 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 17 33 0 ENST00000303868.5:c.700G>A p.Gly234Ser p.G234S ENST00000303868 NM_031951.3 234 Ggc/Agc 0 +WDR90 UCSF GRCh37 16 706475 706475 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 3 16 0 ENST00000293879.4:c.2140C>T p.Gln714Ter p.Q714* ENST00000293879 714 Cag/Tag 0 +WDR91 UCSF GRCh37 7 134873185 134873185 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 74 142 0 ENST00000354475.4:c.1881G>A p.Lys627= p.K627= ENST00000354475 NM_014149.3 627 aaG/aaA 0 +WFDC12 UCSF GRCh37 20 43752816 43752816 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 34 123 0 ENST00000372785.3:c.170G>A p.Gly57Glu p.G57E ENST00000372785 NM_080869.1 57 gGg/gAg 0 +WFDC12 UCSF GRCh37 20 43752779 43752779 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec Untested WXS Illumina HiSeq 65 34 114 0 ENST00000372785.3:c.207G>C p.Lys69Asn p.K69N ENST00000372785 NM_080869.1 69 aaG/aaC 0 +WHSC1 UCSF GRCh37 4 1902712 1902712 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 65 140 0 ENST00000382891.5:c.331C>T p.Pro111Ser p.P111S ENST00000382891 NM_133335.3 111 Ccc/Tcc 0 +WHSC1 UCSF GRCh37 4 1936936 1936936 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 111 213 0 ENST00000382891.5:c.1621G>A p.Ala541Thr p.A541T ENST00000382891 NM_133335.3 541 Gct/Act 0 +WHSC1 UCSF GRCh37 4 1962801 1962801 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 101 208 0 ENST00000382891.5:c.3295G>A p.Glu1099Lys p.E1099K ENST00000382891 NM_133335.3 1099 Gag/Aag 0 +WIPI2 UCSF GRCh37 7 5254295 5254295 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 109 226 0 ENST00000288828.4:c.341G>A p.Ser114Asn p.S114N ENST00000288828 NM_001278299.1 114 aGc/aAc 0 +WIZ UCSF GRCh37 19 15537936 15537936 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 43 91 0 ENST00000263381.7:c.938C>T p.Pro313Leu p.P313L ENST00000263381 NM_021241.2 313 cCc/cTc 0 +WNK3 UCSF GRCh37 X 54259424 54259424 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 89 106 0 ENST00000354646.2:c.4658C>T p.Thr1553Ile p.T1553I ENST00000354646 NM_020922.4 1553 aCc/aTc 0 +WNT1 UCSF GRCh37 12 49373497 49373497 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 24 48 0 ENST00000293549.3:c.351C>T p.Val117= p.V117= ENST00000293549 NM_005430.3 117 gtC/gtT 0 +WNT2B UCSF GRCh37 1 113057690 113057690 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 38 93 0 ENST00000369684.4:c.377C>T p.Thr126Ile p.T126I ENST00000369684 NM_024494.2 126 aCc/aTc 0 +WNT7B UCSF GRCh37 22 46327072 46327072 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 34 103 0 ENST00000339464.4:c.476G>A p.Gly159Asp p.G159D ENST00000339464 NM_058238.2 159 gGc/gAc 0 +WNT9A UCSF GRCh37 1 228109320 228109320 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 26 68 0 ENST00000272164.5:c.997C>T p.Arg333Trp p.R333W ENST00000272164 NM_003395.2 333 Cgg/Tgg 0 +WSB2 UCSF GRCh37 12 118476159 118476159 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 36 77 0 ENST00000315436.3:c.594G>A p.Gln198= p.Q198= ENST00000315436 NM_018639.4 198 caG/caA 0 +WWP2 UCSF GRCh37 16 69964091 69964091 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 61 86 0 ENST00000359154.2:c.1375G>A p.Val459Met p.V459M ENST00000359154 NM_001270454.1 459 Gtg/Atg 0 +WWTR1 UCSF GRCh37 3 149260308 149260308 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 42 108 0 ENST00000360632.3:c.585C>T p.His195= p.H195= ENST00000360632 NM_015472.4 195 caC/caT 0 +XCL2 UCSF GRCh37 1 168510233 168510233 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 67 145 0 ENST00000367819.2:c.302G>A p.Gly101Glu p.G101E ENST00000367819 NM_003175.3 101 gGa/gAa 0 +XCR1 UCSF GRCh37 3 46063248 46063248 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 50 98 0 ENST00000309285.3:c.192C>T p.Ser64= p.S64= ENST00000309285 NM_001024644.1 64 tcC/tcT 0 +XIRP1 UCSF GRCh37 3 39228860 39228860 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 55 103 0 ENST00000340369.3:c.2077G>A p.Val693Met p.V693M ENST00000340369 NM_194293.2 693 Gtg/Atg 0 +XIRP1 UCSF GRCh37 3 39229708 39229708 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 178 133 249 0 ENST00000340369.3:c.1229G>A p.Gly410Asp p.G410D ENST00000340369 NM_194293.2 410 gGt/gAt 0 +XIRP1 UCSF GRCh37 3 39228192 39228192 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 29 83 0 ENST00000340369.3:c.2745G>A p.Arg915= p.R915= ENST00000340369 NM_194293.2 915 cgG/cgA 0 +XIRP2 UCSF GRCh37 2 168103905 168103905 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 77 142 0 ENST00000409195.1:c.6003G>A p.Met2001Ile p.M2001I ENST00000409195 NM_152381.5 2001 atG/atA 0 +XIRP2 UCSF GRCh37 2 168107768 168107768 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 150 101 244 0 ENST00000409195.1:c.9866G>C p.Ser3289Thr p.S3289T ENST00000409195 NM_152381.5 3289 aGt/aCt 0 +XIRP2 UCSF GRCh37 2 168115309 168115309 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 72 198 0 ENST00000409195.1:c.*982G>A *328* ENST00000409195 NM_152381.5 0 +XKR7 UCSF GRCh37 20 30584735 30584735 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 59 136 0 ENST00000562532.2:c.1215C>T p.Ser405= p.S405= ENST00000562532 NM_001011718.1 405 agC/agT 0 +XKRX UCSF GRCh37 X 100169423 100169423 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 147 144 0 ENST00000372956.2:c.1254C>T p.Asp418= p.D418= ENST00000372956 418 gaC/gaT 0 +XPR1 UCSF GRCh37 1 180772570 180772570 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 90 161 0 ENST00000367590.4:c.270G>A p.Glu90= p.E90= ENST00000367590 NM_004736.3 90 gaG/gaA 0 +YSK4 UCSF GRCh37 2 135744645 135744645 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 160 96 248 0 ENST00000375845.3:c.1797G>A p.Lys599= p.K599= ENST00000375845 NM_025052.3 599 aaG/aaA 0 +YTHDC1 UCSF GRCh37 4 69196001 69196001 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 33 100 0 ENST00000344157.4:c.1150G>A p.Glu384Lys p.E384K ENST00000344157 NM_001031732.2 384 Gag/Aag 0 +YTHDC1 UCSF GRCh37 4 69184300 69184300 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 46 83 0 ENST00000344157.4:c.1762-1G>A p.X588_splice ENST00000344157 NM_001031732.2 0 +YTHDC2 UCSF GRCh37 5 112851004 112851004 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 142 92 169 0 ENST00000161863.4:c.223A>G p.Arg75Gly p.R75G ENST00000161863 NM_022828.3 75 Aga/Gga 0 +YTHDF2 UCSF GRCh37 1 29069051 29069051 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 156 109 261 0 ENST00000373812.3:c.269G>A p.Gly90Glu p.G90E ENST00000373812 NM_016258.2 90 gGa/gAa 0 +YY1 UCSF GRCh37 14 100742893 100742893 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 80 190 0 ENST00000262238.4:c.970G>A p.Val324Ile p.V324I ENST00000262238 NM_003403.4 324 Gtc/Atc 0 +YY1 UCSF GRCh37 14 100743830 100743830 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 86 187 0 ENST00000262238.4:c.1138G>A p.Asp380Asn p.D380N ENST00000262238 NM_003403.4 380 Gac/Aac 0 +ZAN UCSF GRCh37 7 100350307 100350307 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 16 15 0 ENST00000546292.1:c.2579C>T p.Pro860Leu p.P860L ENST00000546292 NM_173059.1 860 cCc/cTc 0 +ZAN UCSF GRCh37 7 100383720 100383720 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 128 78 177 0 ENST00000546292.1:c.6933C>T p.Cys2311= p.C2311= ENST00000546292 NM_173059.1 2311 tgC/tgT 0 +ZAN UCSF GRCh37 7 100365518 100365518 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 69 123 0 ENST00000546292.1:c.4925G>A p.Ser1642Asn p.S1642N ENST00000546292 NM_173059.1 1642 aGc/aAc 0 +ZBED4 UCSF GRCh37 22 50278716 50278716 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 91 205 0 ENST00000216268.5:c.1406C>T p.Pro469Leu p.P469L ENST00000216268 NM_014838.2 469 cCc/cTc 0 +ZBTB11 UCSF GRCh37 3 101371436 101371436 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 91 248 0 ENST00000312938.4:c.2548G>A p.Gly850Arg p.G850R ENST00000312938 NM_014415.3 850 Gga/Aga 0 +ZBTB38 UCSF GRCh37 3 141164212 141164212 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 42 84 0 ENST00000321464.5:c.2985G>A p.Gly995= p.G995= ENST00000321464 995 ggG/ggA 0 +ZBTB45 UCSF GRCh37 19 59028884 59028884 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 51 121 0 ENST00000354590.3:c.157G>A p.Ala53Thr p.A53T ENST00000354590 NM_032792.2 53 Gcc/Acc 0 +ZBTB45 UCSF GRCh37 19 59028490 59028490 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 59 126 0 ENST00000354590.3:c.551C>T p.Pro184Leu p.P184L ENST00000354590 NM_032792.2 184 cCc/cTc 0 +ZBTB7C UCSF GRCh37 18 45566509 45566509 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 46 123 0 ENST00000535628.2:c.970C>T p.Pro324Ser p.P324S ENST00000535628 NM_001039360.2 324 Ccc/Tcc 0 +ZC3H12A UCSF GRCh37 1 37948447 37948447 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 51 116 0 ENST00000373087.6:c.1035C>T p.Pro345= p.P345= ENST00000373087 NM_025079.2 345 ccC/ccT 0 +ZC3H12C UCSF GRCh37 11 110035699 110035699 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 143 297 0 ENST00000278590.3:c.1889G>A p.Gly630Glu p.G630E ENST00000278590 NM_033390.1 630 gGg/gAg 0 +ZC3H6 UCSF GRCh37 2 113069414 113069414 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 98 240 0 ENST00000343936.4:c.647G>A p.Gly216Asp p.G216D ENST00000343936 216 gGt/gAt 0 +ZC3H6 UCSF GRCh37 2 113088668 113088668 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 90 195 0 ENST00000343936.4:c.2173G>A p.Glu725Lys p.E725K ENST00000343936 725 Gaa/Aaa 0 +ZC3H6 UCSF GRCh37 2 113089968 113089968 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 153 105 234 0 ENST00000343936.4:c.3473G>A p.Ser1158Asn p.S1158N ENST00000343936 1158 aGc/aAc 0 +ZCCHC14 UCSF GRCh37 16 87445700 87445700 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 25 67 0 ENST00000268616.4:c.2216C>T p.Pro739Leu p.P739L ENST00000268616 NM_015144.2 739 cCt/cTt 0 +ZCWPW2 UCSF GRCh37 3 28476702 28476702 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 94 181 0 ENST00000383768.2:c.434C>T p.Pro145Leu p.P145L ENST00000383768 145 cCc/cTc 0 +ZDHHC17 UCSF GRCh37 12 77244705 77244705 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 176 123 306 0 ENST00000426126.2:c.1839G>A p.Trp613Ter p.W613* ENST00000426126 NM_015336.2 613 tgG/tgA 0 +ZDHHC23 UCSF GRCh37 3 113673143 113673143 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 37 105 0 ENST00000330212.3:c.758C>T p.Pro253Leu p.P253L ENST00000330212 NM_173570.3 253 cCc/cTc 0 +ZEB1 UCSF GRCh37 10 31812964 31812964 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 357 129 302 0 ENST00000320985.10:c.2705G>A p.Gly902Glu p.G902E ENST00000320985 902 gGa/gAa 0 +ZFC3H1 UCSF GRCh37 12 72020039 72020039 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 70 168 0 ENST00000378743.3:c.4317+1G>A p.X1439_splice ENST00000378743 NM_144982.4 0 +ZFHX2 UCSF GRCh37 14 24002695 24002695 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 29 58 0 ENST00000419474.3:c.1840G>A p.Gly614Arg p.G614R ENST00000419474 NM_033400.2 614 Ggg/Agg 0 +ZFHX2 UCSF GRCh37 14 24004210 24004210 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 44 118 0 ENST00000419474.3:c.325G>A p.Asp109Asn p.D109N ENST00000419474 NM_033400.2 109 Gac/Aac 0 +ZFHX3 UCSF GRCh37 16 72829959 72829959 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 144 103 218 0 ENST00000268489.5:c.6622C>T p.Pro2208Ser p.P2208S ENST00000268489 NM_006885.3 2208 Cct/Tct 0 +ZFP30 UCSF GRCh37 19 38126599 38126599 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 93 207 0 ENST00000351218.2:c.843G>A p.Gln281= p.Q281= ENST00000351218 NM_014898.2 281 caG/caA 0 +ZFP92 UCSF GRCh37 X 152686803 152686803 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 1 24 28 0 ENST00000338647.5:c.968G>A p.Arg323His p.R323H ENST00000338647 NM_001136273.1 323 cGc/cAc 0 +ZFPM2 UCSF GRCh37 8 106573677 106573677 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 171 110 254 0 ENST00000407775.2:c.388C>T p.Pro130Ser p.P130S ENST00000407775 NM_012082.3 130 Cct/Tct 0 +ZFY UCSF GRCh37 Y 2829565 2829565 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 24 131 159 0 ENST00000155093.3:c.512T>C p.Ile171Thr p.I171T ENST00000155093 NM_003411.3 171 aTa/aCa 0 +ZFYVE16 UCSF GRCh37 5 79733758 79733758 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 67 154 0 ENST00000338008.5:c.1254G>A p.Gln418= p.Q418= ENST00000338008 NM_014733.3 418 caG/caA 0 +ZFYVE20 UCSF GRCh37 3 15115414 15115414 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 68 163 0 ENST00000253699.3:c.2230G>A p.Asp744Asn p.D744N ENST00000253699 NM_022340.2 744 Gat/Aat 0 +ZFYVE26 UCSF GRCh37 14 68234548 68234548 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 82 155 0 ENST00000347230.4:c.5663G>A p.Ser1888Asn p.S1888N ENST00000347230 NM_015346.3 1888 aGc/aAc 0 +ZFYVE26 UCSF GRCh37 14 68264935 68264935 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 49 130 0 ENST00000347230.4:c.2044G>A p.Glu682Lys p.E682K ENST00000347230 NM_015346.3 682 Gaa/Aaa 0 +ZFYVE28 UCSF GRCh37 4 2306047 2306047 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 48 84 0 ENST00000290974.2:c.2020C>T p.His674Tyr p.H674Y ENST00000290974 NM_020972.2 674 Cac/Tac 0 +ZFYVE9 UCSF GRCh37 1 52803605 52803605 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 33 70 0 ENST00000287727.3:c.3832G>A p.Gly1278Ser p.G1278S ENST00000287727 NM_004799.3 1278 Ggt/Agt 0 +ZKSCAN5 UCSF GRCh37 7 99123443 99123443 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 99 197 0 ENST00000326775.5:c.780G>A p.Glu260= p.E260= ENST00000326775 NM_145102.2 260 gaG/gaA 0 +ZMYM2 UCSF GRCh37 13 20632781 20632781 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 210 111 313 0 ENST00000382871.2:c.2560C>T p.Pro854Ser p.P854S ENST00000382871 854 Cct/Tct 0 +ZNF12 UCSF GRCh37 7 6730763 6730763 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 167 142 250 0 ENST00000405858.1:c.1810G>A p.Ala604Thr p.A604T ENST00000405858 NM_016265.3 604 Gcc/Acc 0 +ZNF133 UCSF GRCh37 20 18296873 18296873 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 71 158 0 ENST00000316358.4:c.1378C>T p.His460Tyr p.H460Y ENST00000316358 NM_001283008.1 460 Cac/Tac 0 +ZNF133 UCSF GRCh37 20 18286988 18286988 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 33 84 0 ENST00000316358.4:c.168G>A p.Gly56= p.G56= ENST00000316358 NM_001283008.1 56 ggG/ggA 0 +ZNF141 UCSF GRCh37 4 367239 367239 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 212 105 306 0 ENST00000240499.7:c.1013C>T p.Pro338Leu p.P338L ENST00000240499 NM_003441.2 338 cCc/cTc 0 +ZNF148 UCSF GRCh37 3 125007042 125007042 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 68 125 0 ENST00000360647.4:c.364G>A p.Asp122Asn p.D122N ENST00000360647 NM_021964.2 122 Gat/Aat 0 +ZNF167 UCSF GRCh37 3 44612845 44612845 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 89 216 0 ENST00000273320.3:c.2243G>A p.Gly748Asp p.G748D ENST00000273320 NM_018651.2 748 gGt/gAt 0 +ZNF189 UCSF GRCh37 9 104171069 104171069 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 167 113 197 0 ENST00000339664.2:c.1019G>A p.Gly340Asp p.G340D ENST00000339664 NM_001278240.1 340 gGc/gAc 0 +ZNF207 UCSF GRCh37 17 30688510 30688510 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 25 82 0 ENST00000321233.6:c.551+524C>T *184* ENST00000321233 NM_003457.3 0 +ZNF208 UCSF GRCh37 19 22156272 22156272 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 104 314 0 ENST00000397126.4:c.1564G>A p.Glu522Lys p.E522K ENST00000397126 NM_007153.3 522 Gag/Aag 0 +ZNF232 UCSF GRCh37 17 5009700 5009700 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 77 198 0 ENST00000250076.3:c.754G>A p.Asp252Asn p.D252N ENST00000250076 NM_014519.2 252 Gac/Aac 0 +ZNF259 UCSF GRCh37 11 116655613 116655613 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 42 96 0 ENST00000227322.3:c.778C>T p.Pro260Ser p.P260S ENST00000227322 NM_003904.3 260 Cca/Tca 0 +ZNF273 UCSF GRCh37 7 64388509 64388509 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 48 167 0 ENST00000319636.5:c.608G>A p.Gly203Asp p.G203D ENST00000319636 203 gGc/gAc 0 +ZNF273 UCSF GRCh37 7 64378666 64378666 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 189 89 244 0 ENST00000319636.5:c.126C>T p.Pro42= p.P42= ENST00000319636 42 ccC/ccT 0 +ZNF274 UCSF GRCh37 19 58718448 58718448 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 19 53 0 ENST00000326804.4:c.616G>A p.Glu206Lys p.E206K ENST00000326804 NM_133502.2 206 Gag/Aag 0 +ZNF276 UCSF GRCh37 16 89804646 89804646 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 17 28 0 ENST00000443381.2:c.1837C>T p.Pro613Ser p.P613S ENST00000443381 NM_001113525.1 613 Ccc/Tcc 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 158 97 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 75 46 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +ZNF281 UCSF GRCh37 1 200376691 200376691 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 98 219 0 ENST00000294740.3:c.2143C>T p.Pro715Ser p.P715S ENST00000294740 NM_001281293.1 715 Cct/Tct 0 +ZNF282 UCSF GRCh37 7 148895529 148895529 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 72 141 0 ENST00000262085.3:c.270G>A p.Gln90= p.Q90= ENST00000262085 NM_003575.2 90 caG/caA 0 +ZNF317 UCSF GRCh37 19 9271310 9271310 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 45 119 0 ENST00000247956.6:c.989G>A p.Gly330Glu p.G330E ENST00000247956 NM_020933.4 330 gGa/gAa 0 +ZNF335 UCSF GRCh37 20 44596467 44596467 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 30 104 0 ENST00000322927.2:c.720G>A p.Val240= p.V240= ENST00000322927 NM_022095.3 240 gtG/gtA 0 +ZNF343 UCSF GRCh37 20 2464326 2464326 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 93 210 0 ENST00000278772.4:c.1281C>T p.His427= p.H427= ENST00000278772 NM_024325.4 427 caC/caT 0 +ZNF418 UCSF GRCh37 19 58437817 58437817 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 93 225 0 ENST00000396147.1:c.1732C>T p.Leu578Phe p.L578F ENST00000396147 NM_133460.1 578 Ctc/Ttc 0 +ZNF432 UCSF GRCh37 19 52537770 52537770 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 166 133 272 0 ENST00000221315.5:c.1162A>G p.Met388Val p.M388V ENST00000221315 NM_014650.2 388 Atg/Gtg 0 +ZNF434 UCSF GRCh37 16 3433147 3433147 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 157 85 134 0 ENST00000396846.3:c.1799C>T p.Thr600Ile p.T600I ENST00000396846 600 aCc/aTc 0 +ZNF440 UCSF GRCh37 19 11943637 11943637 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 99 216 0 ENST00000304060.5:c.1646G>A p.Gly549Glu p.G549E ENST00000304060 NM_152357.2 549 gGa/gAa 0 +ZNF445 UCSF GRCh37 3 44488170 44488170 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 129 275 0 ENST00000396077.2:c.2993G>A p.Arg998Lys p.R998K ENST00000396077 NM_181489.5 998 aGa/aAa 0 +ZNF451 UCSF GRCh37 6 57017077 57017077 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 66 154 0 ENST00000370706.4:c.2811G>A p.Arg937= p.R937= ENST00000370706 NM_001031623.2 937 agG/agA 0 +ZNF462 UCSF GRCh37 9 109688504 109688504 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 102 76 164 0 ENST00000277225.5:c.2311G>A p.Glu771Lys p.E771K ENST00000277225 771 Gag/Aag 0 +ZNF462 UCSF GRCh37 9 109691673 109691673 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 78 150 0 ENST00000277225.5:c.5480G>A p.Gly1827Asp p.G1827D ENST00000277225 1827 gGc/gAc 0 +ZNF473 UCSF GRCh37 19 50542435 50542435 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 65 162 0 ENST00000270617.3:c.27G>A p.Lys9= p.K9= ENST00000270617 NM_015428.1 9 aaG/aaA 0 +ZNF496 UCSF GRCh37 1 247473629 247473629 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 50 106 0 ENST00000294753.4:c.781C>T p.Pro261Ser p.P261S ENST00000294753 NM_032752.1 261 Cca/Tca 0 +ZNF497 UCSF GRCh37 19 58867996 58867996 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 10 18 0 ENST00000311044.3:c.1006G>A p.Gly336Ser p.G336S ENST00000311044 NM_198458.2 336 Ggc/Agc 0 +ZNF500 UCSF GRCh37 16 4815955 4815955 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 42 118 0 ENST00000219478.6:c.25C>T p.Pro9Ser p.P9S ENST00000219478 9 Ccc/Tcc 0 +ZNF500 UCSF GRCh37 16 4815944 4815944 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 58 112 0 ENST00000219478.6:c.36C>T p.Thr12= p.T12= ENST00000219478 12 acC/acT 0 +ZNF513 UCSF GRCh37 2 27600534 27600534 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0011 P18_Rec Untested WXS Illumina HiSeq 25 65 162 0 ENST00000323703.6:c.1504C>T p.Pro502Ser p.P502S ENST00000323703 NM_144631.5 502 Cct/Tct 0 +ZNF516 UCSF GRCh37 18 74091160 74091160 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 27 65 0 ENST00000443185.2:c.2910C>T p.Ala970= p.A970= ENST00000443185 NM_014643.3 970 gcC/gcT 0 +ZNF517 UCSF GRCh37 8 146032905 146032905 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 4 26 0 ENST00000359971.3:c.604G>A p.Ala202Thr p.A202T ENST00000359971 NM_213605.2 202 Gcc/Acc 0 +ZNF518B UCSF GRCh37 4 10445190 10445190 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 163 139 254 0 ENST00000326756.3:c.2763G>A p.Arg921= p.R921= ENST00000326756 NM_053042.2 921 agG/agA 0 +ZNF534 UCSF GRCh37 19 52942513 52942513 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 176 132 271 0 ENST00000332323.6:c.1839T>C p.His613= p.H613= ENST00000332323 NM_001143939.1 613 caT/caC 0 +ZNF540 UCSF GRCh37 19 38090612 38090612 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 90 182 0 ENST00000316433.4:c.95G>A p.Arg32Lys p.R32K ENST00000316433 NM_001172225.2 32 aGa/aAa 0 +ZNF570 UCSF GRCh37 19 37975761 37975761 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 156 119 238 0 ENST00000330173.1:c.1237C>T p.Pro413Ser p.P413S ENST00000330173 NM_144694.1 413 Cct/Tct 0 +ZNF570 UCSF GRCh37 19 37975724 37975724 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 106 191 0 ENST00000330173.1:c.1200C>T p.His400= p.H400= ENST00000330173 NM_144694.1 400 caC/caT 0 +ZNF586 UCSF GRCh37 19 58290725 58290725 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 80 246 0 ENST00000396154.2:c.770C>T p.Thr257Ile p.T257I ENST00000396154 NM_017652.3 257 aCa/aTa 0 +ZNF592 UCSF GRCh37 15 85326026 85326026 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 129 104 226 0 ENST00000299927.3:c.120C>T p.Pro40= p.P40= ENST00000299927 40 ccC/ccT 0 +ZNF608 UCSF GRCh37 5 124079985 124079985 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 62 144 0 ENST00000306315.5:c.698G>A p.Gly233Glu p.G233E ENST00000306315 NM_020747.2 233 gGg/gAg 0 +ZNF621 UCSF GRCh37 3 40571750 40571750 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 57 107 0 ENST00000339296.5:c.202G>A p.Glu68Lys p.E68K ENST00000339296 NM_198484.3 68 Gaa/Aaa 0 +ZNF628 UCSF GRCh37 19 55995469 55995469 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 15 15 0 ENST00000598519.1:c.2909C>T p.Pro970Leu p.P970L ENST00000598519 NM_033113.2 970 cCc/cTc 0 +ZNF646 UCSF GRCh37 16 31088860 31088860 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 15 43 0 ENST00000394979.2:c.1215C>T p.Leu405= p.L405= ENST00000394979 405 ctC/ctT 0 +ZNF648 UCSF GRCh37 1 182026975 182026975 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 56 159 0 ENST00000339948.3:c.171C>T p.Gly57= p.G57= ENST00000339948 NM_001009992.1 57 ggC/ggT 0 +ZNF672 UCSF GRCh37 1 249142351 249142351 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 24 32 0 ENST00000306562.3:c.878G>A p.Gly293Glu p.G293E ENST00000306562 NM_024836.1 293 gGg/gAg 0 +ZNF691 UCSF GRCh37 1 43315411 43315411 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 103 201 0 ENST00000397044.3:c.82G>A p.Glu28Lys p.E28K ENST00000397044 28 Gag/Aag 0 +ZNF77 UCSF GRCh37 19 2936675 2936675 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 66 113 0 ENST00000314531.4:c.158G>A p.Gly53Glu p.G53E ENST00000314531 NM_021217.2 53 gGa/gAa 0 +ZNF778 UCSF GRCh37 16 89294114 89294114 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 158 124 264 0 ENST00000433976.2:c.1334G>A p.Gly445Glu p.G445E ENST00000433976 NM_001201407.1 445 gGa/gAa 0 +ZNF800 UCSF GRCh37 7 127014204 127014204 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 172 108 250 0 ENST00000265827.3:c.1186G>A p.Gly396Ser p.G396S ENST00000265827 NM_176814.3 396 Ggc/Agc 0 +ZNF804B UCSF GRCh37 7 88964016 88964016 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 76 190 0 ENST00000333190.4:c.1720G>A p.Glu574Lys p.E574K ENST00000333190 NM_181646.2 574 Gaa/Aaa 0 +ZNF836 UCSF GRCh37 19 52660411 52660411 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 227 163 330 0 ENST00000597252.1:c.525C>T p.Ser175= p.S175= ENST00000597252 175 tcC/tcT 0 +ZNF846 UCSF GRCh37 19 9868417 9868417 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 87 167 0 ENST00000397902.2:c.1336G>A p.Gly446Arg p.G446R ENST00000397902 NM_001077624.1 446 Gga/Aga 0 +ZNF846 UCSF GRCh37 19 9868865 9868865 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 97 197 0 ENST00000397902.2:c.888C>T p.Tyr296= p.Y296= ENST00000397902 NM_001077624.1 296 taC/taT 0 +ZNF862 UCSF GRCh37 7 149558596 149558596 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 24 58 0 ENST00000223210.4:c.2347G>A p.Asp783Asn p.D783N ENST00000223210 NM_001099220.1 783 Gat/Aat 0 +ZNHIT3 UCSF GRCh37 17 34842624 34842624 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 65 83 0 ENST00000225410.4:c.81G>A p.Val27= p.V27= ENST00000225410 NM_004773.3 27 gtG/gtA 0 +ZPBP UCSF GRCh37 7 49977191 49977191 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 125 78 171 0 ENST00000046087.2:c.989C>T p.Pro330Leu p.P330L ENST00000046087 NM_007009.2 330 cCc/cTc 0 +ZSCAN10 UCSF GRCh37 16 3142133 3142133 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 28 91 0 ENST00000252463.2:c.416C>T p.Pro139Leu p.P139L ENST00000252463 NM_032805.1 139 cCg/cTg 0 +ZSCAN12 UCSF GRCh37 6 28358508 28358508 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 75 184 0 ENST00000361028.1:c.1559C>T p.Thr520Ile p.T520I ENST00000361028 520 aCt/aTt 0 +ZSCAN2 UCSF GRCh37 15 85164774 85164774 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 69 135 0 ENST00000448803.2:c.1348G>A p.Val450Met p.V450M ENST00000448803 NM_181877.3 450 Gtg/Atg 0 +ZSWIM1 UCSF GRCh37 20 44512582 44512582 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 57 92 0 ENST00000372520.1:c.1351G>A p.Gly451Ser p.G451S ENST00000372520 451 Ggt/Agt 0 +ZSWIM2 UCSF GRCh37 2 187702039 187702039 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 89 204 0 ENST00000295131.2:c.737G>A p.Cys246Tyr p.C246Y ENST00000295131 NM_182521.2 246 tGt/tAt 0 +ZWILCH UCSF GRCh37 15 66807978 66807978 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 57 134 0 ENST00000307897.5:c.316G>A p.Ala106Thr p.A106T ENST00000307897 NM_017975.3 106 Gca/Aca 0 +ZYG11B UCSF GRCh37 1 53250719 53250719 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 49 111 0 ENST00000294353.6:c.1263C>T p.His421= p.H421= ENST00000294353 NM_024646.2 421 caC/caT 0 +ATRX UCSF GRCh37 X 76845402 76845403 + frameshift_variant Frame_Shift_Del DEL AA AA - NOVEL P21_Pri Untested WXS Illumina HiSeq 36 0 ENST00000373344.5:c.6118_6119del p.Phe2040GlnfsTer11 p.F2040Qfs*11 ENST00000373344 NM_000489.3 2040 TTc/c 0 +CAPN12 UCSF GRCh37 19 39228950 39228950 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 10 8 53 0 ENST00000328867.4:c.928G>A p.Asp310Asn p.D310N ENST00000328867 NM_144691.3 310 Gat/Aat 0 +CDC16 UCSF GRCh37 13 115002355 115002355 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 74 58 95 0 ENST00000356221.3:c.185C>T p.Ser62Leu p.S62L ENST00000356221 62 tCa/tTa 0 +CDKN1B UCSF GRCh37 12 12870849 12870849 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P21_Pri somatic WXS Sanger Illumina HiSeq 186 0 ENST00000228872.4:c.78del p.Ser27ArgfsTer15 p.S27Rfs*15 ENST00000228872 NM_004064.3 26 Ccc/cc 0 +CENPE UCSF GRCh37 4 104066758 104066758 + synonymous_variant Silent SNP C C G NOVEL P21_Pri Untested WXS Illumina HiSeq 134 17 239 0 ENST00000265148.3:c.4494G>C p.Val1498= p.V1498= ENST00000265148 NM_001813.2 1498 gtG/gtC 0 +COL6A3 UCSF GRCh37 2 238289888 238289888 + synonymous_variant Silent SNP G G A NOVEL P21_Pri Untested WXS Illumina HiSeq 130 32 303 0 ENST00000295550.4:c.1567C>T p.Leu523= p.L523= ENST00000295550 NM_004369.3 523 Ctg/Ttg 0 +DENND2D UCSF GRCh37 1 111740573 111740573 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 40 20 48 0 ENST00000357640.4:c.395G>A p.Ser132Asn p.S132N ENST00000357640 NM_024901.4 132 aGc/aAc 0 +HIST1H2AH UCSF GRCh37 6 27115070 27115070 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Pri Untested WXS Illumina HiSeq 100 56 280 0 ENST00000377459.1:c.163G>C p.Val55Leu p.V55L ENST00000377459 NM_080596.2 55 Gtg/Ctg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 55 41 126 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +INPPL1 UCSF GRCh37 11 71948227 71948227 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Pri Untested WXS Illumina HiSeq 96 56 223 0 ENST00000298229.2:c.2939G>C p.Ser980Thr p.S980T ENST00000298229 NM_001567.3 980 aGc/aCc 0 +KDM5A UCSF GRCh37 12 416215 416215 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Pri Untested WXS Illumina HiSeq 275 110 339 0 ENST00000399788.2:c.3971T>C p.Val1324Ala p.V1324A ENST00000399788 NM_001042603.1 1324 gTg/gCg 0 +KIAA0020 UCSF GRCh37 9 2837245 2837245 + missense_variant Missense_Mutation SNP T T A NOVEL P21_Pri Untested WXS Illumina HiSeq 223 235 542 0 ENST00000397885.2:c.239A>T p.Asn80Ile p.N80I ENST00000397885 NM_014878.4 80 aAc/aTc 0 +KIF6 UCSF GRCh37 6 39563952 39563952 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Pri Untested WXS Illumina HiSeq 61 30 98 0 ENST00000287152.7:c.724C>T p.Arg242Ter p.R242* ENST00000287152 NM_145027.4 242 Cga/Tga 0 +LTB4R UCSF GRCh37 14 24785606 24785606 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 15 6 21 0 ENST00000345363.3:c.749C>T p.Ala250Val p.A250V ENST00000345363 250 gCc/gTc 0 +NBPF10 UCSF GRCh37 1 145327548 145327548 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Pri Untested WXS Illumina HiSeq 47 11 17 0 ENST00000342960.5:c.4105A>G p.Asn1369Asp p.N1369D ENST00000342960 NM_001039703.5 1369 Aat/Gat 0 +NECAP2 UCSF GRCh37 1 16767274 16767274 + synonymous_variant Silent SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 45 8 103 0 ENST00000337132.5:c.18C>T p.Tyr6= p.Y6= ENST00000337132 NM_018090.4 6 taC/taT 0 +NPY UCSF GRCh37 7 24324899 24324899 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Pri Untested WXS Illumina HiSeq 39 19 106 0 ENST00000242152.2:c.40C>G p.Leu14Val p.L14V ENST00000242152 NM_000905.3 14 Ctc/Gtc 0 +PIK3AP1 UCSF GRCh37 10 98405415 98405415 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Pri somatic WXS Sanger Illumina HiSeq 67 16 144 0 ENST00000339364.5:c.1190C>T p.Thr397Met p.T397M ENST00000339364 NM_152309.2 397 aCg/aTg 0 +RAP1GAP2 UCSF GRCh37 17 2908700 2908700 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Pri Untested WXS Illumina HiSeq 216 115 544 0 ENST00000254695.8:c.1238G>T p.Gly413Val p.G413V ENST00000254695 NM_015085.4 413 gGt/gTt 0 +SCAF4 UCSF GRCh37 21 33058004 33058004 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Pri Untested WXS Illumina HiSeq 34 23 62 0 ENST00000286835.7:c.2086C>T p.Gln696Ter p.Q696* ENST00000286835 NM_020706.2 696 Cag/Tag 0 +SPTBN4 UCSF GRCh37 19 41019235 41019235 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Pri Untested WXS Illumina HiSeq 14 5 24 0 ENST00000352632.3:c.2539C>A p.Pro847Thr p.P847T ENST00000352632 847 Cca/Aca 0 +TBX2 UCSF GRCh37 17 59479224 59479224 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Pri Untested WXS Illumina HiSeq 52 8 116 0 ENST00000240328.3:c.575G>T p.Ser192Ile p.S192I ENST00000240328 NM_005994.3 192 aGc/aTc 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Pri somatic WXS Sanger Illumina HiSeq 52 40 129 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TP53 UCSF GRCh37 17 7578388 7578388 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Pri Untested WXS Illumina HiSeq 46 31 127 0 ENST00000269305.4:c.542G>C p.Arg181Pro p.R181P ENST00000269305 NM_001126112.2 181 cGc/cCc 0 +TRDN UCSF GRCh37 6 123824996 123824996 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P21_Pri Untested WXS Illumina HiSeq 29 0 ENST00000334268.4:c.661del p.Glu221LysfsTer2 p.E221Kfs*2 ENST00000334268 221 Gaa/aa 0 +UNC5B UCSF GRCh37 10 73051501 73051501 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Pri Untested WXS Illumina HiSeq 32 7 88 0 ENST00000335350.6:c.1607G>C p.Gly536Ala p.G536A ENST00000335350 NM_170744.4 536 gGc/gCc 0 +UNC5B UCSF GRCh37 10 73051475 73051475 + synonymous_variant Silent SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 51 9 104 0 ENST00000335350.6:c.1581C>T p.Ala527= p.A527= ENST00000335350 NM_170744.4 527 gcC/gcT 0 +A2ML1 UCSF GRCh37 12 9001452 9001452 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 368 58 422 0 ENST00000299698.7:c.1970G>A p.Arg657His p.R657H ENST00000299698 NM_144670.4 657 cGt/cAt 0 +AADACL3 UCSF GRCh37 1 12785370 12785370 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 241 63 313 0 ENST00000359318.5:c.460G>A p.Asp154Asn p.D154N ENST00000359318 NM_001103170.1 154 Gat/Aat 0 +ABCB4 UCSF GRCh37 7 87068997 87068997 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 101 39 179 0 ENST00000265723.4:c.1717G>T p.Ala573Ser p.A573S ENST00000265723 NM_000443.3 573 Gca/Tca 0 +ABCC1 UCSF GRCh37 16 16184294 16184294 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 48 11 72 0 ENST00000399410.3:c.2493C>T p.Tyr831= p.Y831= ENST00000399410 NM_004996.3 831 taC/taT 0 +ABR UCSF GRCh37 17 995003 995003 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 135 26 188 1 ENST00000302538.5:c.433G>A p.Asp145Asn p.D145N ENST00000302538 NM_021962.3 145 Gac/Aac 0 +ABR UCSF GRCh37 17 914089 914089 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 28 181 0 ENST00000302538.5:c.2116C>T p.Leu706= p.L706= ENST00000302538 NM_021962.3 706 Ctg/Ttg 0 +ACACA UCSF GRCh37 17 35598915 35598915 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 109 22 118 0 ENST00000353139.5:c.2986G>A p.Glu996Lys p.E996K ENST00000353139 NM_198834.1 996 Gaa/Aaa 0 +ACBD4 UCSF GRCh37 17 43214454 43214454 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 74 17 110 0 ENST00000376955.4:c.363G>A p.Gln121= p.Q121= ENST00000376955 NM_001135707.1 121 caG/caA 0 +ACE UCSF GRCh37 17 61574338 61574338 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 34 6 49 0 ENST00000290866.4:c.3683C>T p.Pro1228Leu p.P1228L ENST00000290866 NM_000789.3 1228 cCg/cTg 0 +ACO1 UCSF GRCh37 9 32431790 32431790 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 26 127 0 ENST00000309951.6:c.1800G>A p.Glu600= p.E600= ENST00000309951 NM_002197.2 600 gaG/gaA 0 +ACRC UCSF GRCh37 X 70832774 70832774 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 43 7 46 0 ENST00000373695.1:c.2018C>T p.Ser673Phe p.S673F ENST00000373695 673 tCt/tTt 0 +ACTL7B UCSF GRCh37 9 111617807 111617807 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 84 55 151 0 ENST00000374667.3:c.404G>A p.Arg135His p.R135H ENST00000374667 NM_006686.3 135 cGc/cAc 0 +ACTR1A UCSF GRCh37 10 104241629 104241629 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 126 39 258 0 ENST00000369905.4:c.952G>A p.Val318Met p.V318M ENST00000369905 NM_005736.3 318 Gtg/Atg 0 +ACTR8 UCSF GRCh37 3 53916017 53916017 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 14 6 34 0 ENST00000335754.3:c.112T>C p.Ser38Pro p.S38P ENST00000335754 NM_022899.4 38 Tcg/Ccg 0 +ADAMTS15 UCSF GRCh37 11 130318956 130318956 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 27 19 93 0 ENST00000299164.2:c.88C>T p.Arg30Ter p.R30* ENST00000299164 NM_139055.2 30 Cga/Tga 0 +ADAP1 UCSF GRCh37 7 938844 938844 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 15 142 0 ENST00000265846.5:c.922G>T p.Val308Leu p.V308L ENST00000265846 NM_006869.2 308 Gtg/Ttg 0 +ADCY9 UCSF GRCh37 16 4016763 4016763 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 280 79 526 0 ENST00000294016.3:c.3075G>A p.Arg1025= p.R1025= ENST00000294016 NM_001116.3 1025 cgG/cgA 0 +ADNP UCSF GRCh37 20 49509195 49509195 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 194 60 286 0 ENST00000349014.3:c.2056C>T p.His686Tyr p.H686Y ENST00000349014 NM_001282532.1 686 Cac/Tac 0 +AGAP3 UCSF GRCh37 7 150839618 150839618 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 85 10 107 0 ENST00000397238.2:c.2170C>T p.Pro724Ser p.P724S ENST00000397238 NM_031946.5 724 Cct/Tct 0 +AGBL1 UCSF GRCh37 15 87531263 87531263 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 412 96 492 0 ENST00000441037.2:c.3129C>T p.Tyr1043= p.Y1043= ENST00000441037 NM_152336.2 1043 taC/taT 0 +AGBL3 UCSF GRCh37 7 134719029 134719029 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 37 195 0 ENST00000436302.2:c.687C>T p.Thr229= p.T229= ENST00000436302 NM_178563.3 229 acC/acT 0 +AGPAT5 UCSF GRCh37 8 6605321 6605321 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 114 30 123 0 ENST00000285518.6:c.717G>A p.Gly239= p.G239= ENST00000285518 NM_018361.3 239 ggG/ggA 0 +AGTR1 UCSF GRCh37 3 148458912 148458912 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 37 134 0 ENST00000349243.3:c.90G>A p.Met30Ile p.M30I ENST00000349243 NM_000685.4 30 atG/atA 0 +AHNAK UCSF GRCh37 11 62300649 62300649 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 125 19 164 0 ENST00000378024.4:c.1240G>A p.Glu414Lys p.E414K ENST00000378024 NM_001620.2 414 Gaa/Aaa 0 +AHNAK2 UCSF GRCh37 14 105414940 105414940 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 400 153 852 0 ENST00000333244.5:c.6848G>A p.Ser2283Asn p.S2283N ENST00000333244 NM_138420.2 2283 aGc/aAc 0 +AHNAK2 UCSF GRCh37 14 105418590 105418590 + synonymous_variant Silent SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 354 125 656 0 ENST00000333244.5:c.3198C>G p.Leu1066= p.L1066= ENST00000333244 NM_138420.2 1066 ctC/ctG 0 +AKAP13 UCSF GRCh37 15 86284312 86284312 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 30 12 71 0 ENST00000394518.2:c.7644C>T p.Asp2548= p.D2548= ENST00000394518 NM_007200.4 2548 gaC/gaT 0 +AKAP6 UCSF GRCh37 14 33046434 33046434 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 120 23 151 0 ENST00000280979.4:c.2455C>T p.Leu819= p.L819= ENST00000280979 NM_004274.4 819 Ctg/Ttg 0 +AKAP9 UCSF GRCh37 7 91631287 91631287 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 11 113 0 ENST00000356239.3:c.2056G>A p.Asp686Asn p.D686N ENST00000356239 NM_147185.2 686 Gac/Aac 0 +AKT2 UCSF GRCh37 19 40747844 40747844 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 48 17 84 0 ENST00000392038.2:c.573+1G>A p.X191_splice ENST00000392038 NM_001626.4 0 +ALDH3B1 UCSF GRCh37 11 67790122 67790122 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 64 11 95 0 ENST00000342456.6:c.895G>A p.Gly299Arg p.G299R ENST00000342456 NM_001030010.1 299 Ggg/Agg 0 +ALDH6A1 UCSF GRCh37 14 74539242 74539242 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 30 154 0 ENST00000553458.1:c.184C>T p.Pro62Ser p.P62S ENST00000553458 NM_001278593.1 62 Cca/Tca 0 +ALG12 UCSF GRCh37 22 50307094 50307094 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 39 196 0 ENST00000330817.6:c.234C>T p.Ser78= p.S78= ENST00000330817 NM_024105.3 78 tcC/tcT 0 +ALG13 UCSF GRCh37 X 111003111 111003111 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 100 80 172 1 ENST00000394780.3:c.3298C>T p.Pro1100Ser p.P1100S ENST00000394780 NM_001257231.1 1100 Cca/Tca 0 +ALK UCSF GRCh37 2 29430102 29430102 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 54 22 85 1 ENST00000389048.3:c.3873G>A p.Leu1291= p.L1291= ENST00000389048 NM_004304.4 1291 ctG/ctA 0 +ALMS1 UCSF GRCh37 2 73786249 73786249 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 68 12 112 0 ENST00000264448.6:c.10361C>T p.Ser3454Phe p.S3454F ENST00000264448 NM_015120.4 3454 tCc/tTc 0 +ALOX15 UCSF GRCh37 17 4542834 4542834 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 54 12 77 1 ENST00000293761.3:c.228G>A p.Trp76Ter p.W76* ENST00000293761 NM_001140.3 76 tgG/tgA 0 +ALOX5 UCSF GRCh37 10 45907762 45907762 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 91 23 138 0 ENST00000374391.2:c.554+1G>A p.X185_splice ENST00000374391 NM_000698.3 0 +ALS2 UCSF GRCh37 2 202589068 202589068 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 141 43 248 1 ENST00000264276.6:c.3462G>A p.Gln1154= p.Q1154= ENST00000264276 NM_020919.3 1154 caG/caA 0 +ALS2 UCSF GRCh37 2 202598137 202598137 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 40 18 49 0 ENST00000264276.6:c.2442G>A p.Glu814= p.E814= ENST00000264276 NM_020919.3 814 gaG/gaA 0 +AMOTL2 UCSF GRCh37 3 134078188 134078188 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 78 13 122 0 ENST00000422605.2:c.2041G>A p.Gly681Ser p.G681S ENST00000422605 681 Ggc/Agc 0 +ANGPTL1 UCSF GRCh37 1 178822772 178822772 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 155 41 179 0 ENST00000234816.2:c.974C>T p.Thr325Ile p.T325I ENST00000234816 NM_004673.3 325 aCa/aTa 0 +ANK1 UCSF GRCh37 8 41550641 41550641 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 96 31 120 0 ENST00000347528.4:c.3611C>T p.Thr1204Ile p.T1204I ENST00000347528 NM_020477.2 1204 aCc/aTc 0 +AP2A1 UCSF GRCh37 19 50304848 50304848 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 82 20 140 0 ENST00000359032.5:c.1755C>T p.Thr585= p.T585= ENST00000359032 NM_014203.2 585 acC/acT 0 +AP2B1 UCSF GRCh37 17 33984689 33984689 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 97 30 139 0 ENST00000312678.8:c.1868C>T p.Ser623Phe p.S623F ENST00000312678 NM_001030006.1 623 tCt/tTt 0 +AP3B1 UCSF GRCh37 5 77396850 77396850 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 22 3 19 0 ENST00000255194.6:c.2398-1G>A p.X800_splice ENST00000255194 0 +APC UCSF GRCh37 5 112174811 112174811 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 164 49 209 0 ENST00000257430.4:c.3520G>A p.Asp1174Asn p.D1174N ENST00000257430 NM_000038.5 1174 Gat/Aat 0 +ARHGAP15 UCSF GRCh37 2 144314015 144314015 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 159 43 262 0 ENST00000295095.6:c.964C>T p.Leu322= p.L322= ENST00000295095 NM_018460.3 322 Ctg/Ttg 0 +ARHGAP31 UCSF GRCh37 3 119134420 119134420 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 78 25 111 0 ENST00000264245.4:c.3644C>T p.Pro1215Leu p.P1215L ENST00000264245 NM_020754.2 1215 cCc/cTc 0 +ARHGAP32 UCSF GRCh37 11 128840445 128840445 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 107 26 157 0 ENST00000310343.9:c.4621G>A p.Gly1541Arg p.G1541R ENST00000310343 NM_001142685.1 1541 Gga/Aga 0 +ARHGEF2 UCSF GRCh37 1 155920170 155920170 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 101 33 160 1 ENST00000361247.4:c.2807G>A p.Arg936Gln p.R936Q ENST00000361247 NM_001162384.1 936 cGg/cAg 0 +ARL13A UCSF GRCh37 X 100240728 100240728 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 159 114 345 0 ENST00000450457.2:c.203C>T p.Ser68Phe p.S68F ENST00000450457 68 tCc/tTc 0 +ARMC5 UCSF GRCh37 16 31478036 31478036 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 16 3 22 0 ENST00000268314.4:c.2634C>T p.Pro878= p.P878= ENST00000268314 NM_001105247.1 878 ccC/ccT 0 +ARNT UCSF GRCh37 1 150788827 150788827 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 19 62 0 ENST00000358595.5:c.1858C>T p.Gln620Ter p.Q620* ENST00000358595 NM_178427.2 620 Cag/Tag 0 +ARPM1 UCSF GRCh37 3 169485464 169485464 + missense_variant Missense_Mutation SNP G G A snp132_rs55656133 P21_Rec Untested WXS Illumina HiSeq 237 56 287 1 ENST00000330368.2:c.875C>T p.Ser292Phe p.S292F ENST00000330368 NM_032487.4 292 tCc/tTc 0 +ASCC3 UCSF GRCh37 6 101247327 101247327 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 41 17 106 0 ENST00000369162.2:c.1249G>A p.Ala417Thr p.A417T ENST00000369162 NM_006828.2 417 Gca/Aca 0 +ASXL1 UCSF GRCh37 20 31024066 31024066 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 153 33 212 1 ENST00000375687.4:c.3551C>T p.Thr1184Ile p.T1184I ENST00000375687 NM_015338.5 1184 aCa/aTa 0 +ASXL1 UCSF GRCh37 20 31023784 31023784 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 224 77 359 0 ENST00000375687.4:c.3269G>A p.Arg1090Lys p.R1090K ENST00000375687 NM_015338.5 1090 aGa/aAa 0 +ATG4A UCSF GRCh37 X 107381120 107381120 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 27 183 275 0 ENST00000372232.3:c.634G>A p.Gly212Ser p.G212S ENST00000372232 NM_052936.3 212 Ggc/Agc 0 +ATP13A4 UCSF GRCh37 3 193156272 193156272 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 46 30 122 0 ENST00000342695.4:c.2664C>T p.His888= p.H888= ENST00000342695 NM_032279.2 888 caC/caT 0 +ATP1A2 UCSF GRCh37 1 160105700 160105700 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 221 33 268 1 ENST00000361216.3:c.2356C>T p.Pro786Ser p.P786S ENST00000361216 NM_000702.3 786 Ccc/Tcc 0 +ATP5L UCSF GRCh37 11 118279715 118279715 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 15 9 35 0 ENST00000300688.3:c.214G>A p.Glu72Lys p.E72K ENST00000300688 NM_006476.4 72 Gaa/Aaa 0 +ATP5S UCSF GRCh37 14 50789230 50789230 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 12 167 0 ENST00000311459.7:c.154G>A p.Val52Met p.V52M ENST00000311459 NM_001003803.2 52 Gtg/Atg 0 +ATP6V1B1 UCSF GRCh37 2 71187101 71187101 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 71 32 159 0 ENST00000234396.4:c.478C>T p.Pro160Ser p.P160S ENST00000234396 NM_001692.3 160 Ccc/Tcc 0 +ATRX UCSF GRCh37 X 76845402 76845403 + frameshift_variant Frame_Shift_Del DEL AA AA - NOVEL P21_Rec Untested WXS Illumina HiSeq 23 0 ENST00000373344.5:c.6118_6119del p.Phe2040GlnfsTer11 p.F2040Qfs*11 ENST00000373344 NM_000489.3 2040 TTc/c 0 +B4GALNT1 UCSF GRCh37 12 58024853 58024853 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 55 285 0 ENST00000341156.4:c.400G>A p.Asp134Asn p.D134N ENST00000341156 NM_001478.4 134 Gac/Aac 0 +B7H6 UCSF GRCh37 11 17388734 17388734 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 94 57 286 1 ENST00000338965.4:c.600C>T p.Ile200= p.I200= ENST00000338965 NM_001202439.1 200 atC/atT 0 +BAAT UCSF GRCh37 9 104130406 104130406 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 52 20 78 0 ENST00000259407.2:c.665C>T p.Pro222Leu p.P222L ENST00000259407 NM_001127610.1 222 cCa/cTa 0 +BAG3 UCSF GRCh37 10 121429613 121429613 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 42 27 165 0 ENST00000369085.3:c.431C>T p.Thr144Ile p.T144I ENST00000369085 NM_004281.3 144 aCc/aTc 0 +BAHCC1 UCSF GRCh37 17 79410157 79410157 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 30 9 61 0 ENST00000307745.7:c.1782G>A p.Met594Ile p.M594I ENST00000307745 594 atG/atA 0 +BARD1 UCSF GRCh37 2 215645709 215645709 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 103 28 196 0 ENST00000260947.4:c.889G>A p.Val297Ile p.V297I ENST00000260947 NM_000465.2 297 Gta/Ata 0 +BARD1 UCSF GRCh37 2 215593469 215593469 + synonymous_variant Silent SNP G G A snp132_rs13389324 P21_Rec Untested WXS Illumina HiSeq 78 27 133 0 ENST00000260947.4:c.2265C>T p.Val755= p.V755= ENST00000260947 NM_000465.2 755 gtC/gtT 0 +BATF2 UCSF GRCh37 11 64756758 64756758 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 65 16 85 0 ENST00000301887.4:c.668C>T p.Pro223Leu p.P223L ENST00000301887 NM_138456.3 223 cCc/cTc 0 +BBS1 UCSF GRCh37 11 66283345 66283345 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 18 120 0 ENST00000318312.7:c.532G>A p.Glu178Lys p.E178K ENST00000318312 NM_024649.4 178 Gag/Aag 0 +BCR UCSF GRCh37 22 23523778 23523778 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 96 28 158 0 ENST00000305877.8:c.631G>A p.Glu211Lys p.E211K ENST00000305877 NM_004327.3 211 Gag/Aag 0 +BDH2 UCSF GRCh37 4 104016418 104016418 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 57 37 120 0 ENST00000296424.4:c.93C>T p.Ala31= p.A31= ENST00000296424 NM_020139.3 31 gcC/gcT 0 +BICC1 UCSF GRCh37 10 60556125 60556125 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 108 29 191 0 ENST00000373886.3:c.1205G>A p.Arg402Gln p.R402Q ENST00000373886 NM_001080512.1 402 cGa/cAa 0 +BIRC6 UCSF GRCh37 2 32656086 32656086 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 147 49 324 0 ENST00000421745.2:c.3176C>T p.Pro1059Leu p.P1059L ENST00000421745 NM_016252.3 1059 cCt/cTt 0 +BMI1 UCSF GRCh37 10 22615405 22615405 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 257 53 231 0 ENST00000376663.3:c.27C>T p.Ile9= p.I9= ENST00000376663 NM_005180.8 9 atC/atT 0 +BOD1L UCSF GRCh37 4 13605438 13605438 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 404 107 475 1 ENST00000040738.5:c.3086G>A p.Ser1029Asn p.S1029N ENST00000040738 NM_148894.2 1029 aGt/aAt 0 +BPNT1 UCSF GRCh37 1 220236275 220236275 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 107 26 125 0 ENST00000322067.7:c.496G>A p.Gly166Arg p.G166R ENST00000322067 NM_006085.4 166 Ggg/Agg 0 +BPTF UCSF GRCh37 17 65850839 65850839 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 114 18 112 0 ENST00000321892.4:c.1397G>A p.Ser466Asn p.S466N ENST00000321892 466 aGt/aAt 0 +BRCA2 UCSF GRCh37 13 32907452 32907452 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 4 78 0 ENST00000380152.3:c.1837C>T p.Leu613= p.L613= ENST00000380152 613 Cta/Tta 0 +BRIP1 UCSF GRCh37 17 59871087 59871087 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 68 22 91 0 ENST00000259008.2:c.1344G>A p.Trp448Ter p.W448* ENST00000259008 NM_032043.2 448 tgG/tgA 0 +BTN2A1 UCSF GRCh37 6 26468761 26468761 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 485 74 352 1 ENST00000312541.5:c.1568C>T p.Thr523Ile p.T523I ENST00000312541 NM_007049.4 523 aCc/aTc 0 +BTNL3 UCSF GRCh37 5 180419994 180419994 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 77 61 272 0 ENST00000342868.6:c.231G>A p.Gln77= p.Q77= ENST00000342868 NM_197975.2 77 caG/caA 0 +BTNL8 UCSF GRCh37 5 180335635 180335635 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 26 187 0 ENST00000340184.4:c.99G>A p.Gly33= p.G33= ENST00000340184 NM_001040462.2 33 ggG/ggA 0 +BUB3 UCSF GRCh37 10 124919988 124919988 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 60 45 212 0 ENST00000368865.4:c.483G>A p.Val161= p.V161= ENST00000368865 NM_004725.3 161 gtG/gtA 0 +C11orf30 UCSF GRCh37 11 76207340 76207340 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 171 61 229 0 ENST00000334736.3:c.1190T>C p.Leu397Pro p.L397P ENST00000334736 NM_020193.3 397 cTt/cCt 0 +C11orf91 UCSF GRCh37 11 33719981 33719981 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 29 21 101 0 ENST00000379011.4:c.576C>T p.Leu192= p.L192= ENST00000379011 NM_001166692.1 192 ctC/ctT 0 +C12orf4 UCSF GRCh37 12 4609359 4609359 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 149 21 121 0 ENST00000261250.3:c.1385C>T p.Thr462Ile p.T462I ENST00000261250 NM_020374.2 462 aCc/aTc 0 +C15orf43 UCSF GRCh37 15 45258369 45258369 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 29 10 30 0 ENST00000340827.3:c.362C>T p.Thr121Ile p.T121I ENST00000340827 NM_152448.2 121 aCa/aTa 0 +C17orf101 UCSF GRCh37 17 80373330 80373330 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 165 47 221 0 ENST00000313056.5:c.248G>A p.Gly83Glu p.G83E ENST00000313056 NM_024648.2 83 gGg/gAg 0 +C1orf112 UCSF GRCh37 1 169819407 169819407 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 42 8 44 0 ENST00000286031.6:c.2165G>A p.Gly722Glu p.G722E ENST00000286031 NM_018186.2 722 gGa/gAa 0 +C1QC UCSF GRCh37 1 22974090 22974090 + synonymous_variant Silent SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 182 59 340 0 ENST00000374637.1:c.552C>G p.Arg184= p.R184= ENST00000374637 184 cgC/cgG 0 +C20orf194 UCSF GRCh37 20 3236766 3236766 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 120 25 171 0 ENST00000252032.9:c.3147C>T p.Asp1049= p.D1049= ENST00000252032 NM_001009984.2 1049 gaC/gaT 0 +C2CD3 UCSF GRCh37 11 73785467 73785467 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 125 28 149 0 ENST00000334126.7:c.4782C>T p.Leu1594= p.L1594= ENST00000334126 NM_001286577.1 1594 ctC/ctT 0 +C2orf18 UCSF GRCh37 2 26997143 26997143 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 82 19 138 0 ENST00000344420.5:c.102G>A p.Glu34= p.E34= ENST00000344420 NM_017877.3 34 gaG/gaA 0 +C3orf39 UCSF GRCh37 3 43122166 43122166 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 105 53 208 1 ENST00000344697.2:c.758C>A p.Pro253Gln p.P253Q ENST00000344697 NM_032806.5 253 cCg/cAg 0 +C3orf39 UCSF GRCh37 3 43121571 43121571 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 33 131 0 ENST00000344697.2:c.1353G>A p.Lys451= p.K451= ENST00000344697 NM_032806.5 451 aaG/aaA 0 +C6orf138 UCSF GRCh37 6 47847449 47847449 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 521 67 388 0 ENST00000339488.4:c.1131G>A p.Leu377= p.L377= ENST00000339488 NM_001013732.3 377 ttG/ttA 0 +C9orf172 UCSF GRCh37 9 139739679 139739679 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 27 10 33 0 ENST00000436881.1:c.813C>T p.Pro271= p.P271= ENST00000436881 NM_001080482.2 271 ccC/ccT 0 +C9orf84 UCSF GRCh37 9 114490030 114490030 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 161 33 146 0 ENST00000318737.4:c.1525G>A p.Glu509Lys p.E509K ENST00000318737 NM_173521.3 509 Gaa/Aaa 0 +C9orf96 UCSF GRCh37 9 136270002 136270002 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 98 28 166 0 ENST00000371957.3:c.1822C>T p.Pro608Ser p.P608S ENST00000371957 NM_153710.4 608 Ccg/Tcg 0 +CA7 UCSF GRCh37 16 66886645 66886645 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 10 98 0 ENST00000338437.2:c.547C>T p.Pro183Ser p.P183S ENST00000338437 NM_005182.2 183 Ccc/Tcc 0 +CAD UCSF GRCh37 2 27447343 27447343 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 110 17 152 0 ENST00000264705.4:c.1239C>T p.Asp413= p.D413= ENST00000264705 NM_004341.3 413 gaC/gaT 0 +CAMKK2 UCSF GRCh37 12 121711942 121711942 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 19 9 23 0 ENST00000324774.5:c.388C>T p.Pro130Ser p.P130S ENST00000324774 NM_006549.3 130 Ccc/Tcc 0 +CAP2 UCSF GRCh37 6 17551772 17551772 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 215 34 194 0 ENST00000229922.2:c.1287C>T p.Asp429= p.D429= ENST00000229922 NM_006366.2 429 gaC/gaT 0 +CAPN12 UCSF GRCh37 19 39228950 39228950 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 31 22 53 0 ENST00000328867.4:c.928G>A p.Asp310Asn p.D310N ENST00000328867 NM_144691.3 310 Gat/Aat 0 +CAPN9 UCSF GRCh37 1 230891097 230891097 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 86 20 118 0 ENST00000271971.2:c.228C>T p.Asn76= p.N76= ENST00000271971 NM_006615.2 76 aaC/aaT 0 +CARD6 UCSF GRCh37 5 40841605 40841605 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 107 39 144 0 ENST00000254691.5:c.121G>A p.Glu41Lys p.E41K ENST00000254691 NM_032587.3 41 Gag/Aag 0 +CASD1 UCSF GRCh37 7 94168278 94168278 + splice_acceptor_variant Splice_Site SNP G G A snp132_rs115186017 P21_Rec Untested WXS Illumina HiSeq 51 21 65 0 ENST00000297273.4:c.1267-1G>A p.X423_splice ENST00000297273 NM_022900.4 0 +CASKIN2 UCSF GRCh37 17 73499007 73499007 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 9 57 0 ENST00000321617.3:c.2148C>T p.Ala716= p.A716= ENST00000321617 NM_020753.4 716 gcC/gcT 0 +CASZ1 UCSF GRCh37 1 10720283 10720283 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 77 31 103 0 ENST00000377022.3:c.816C>T p.Thr272= p.T272= ENST00000377022 NM_001079843.2 272 acC/acT 0 +CAT UCSF GRCh37 11 34472578 34472578 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 116 63 275 0 ENST00000241052.4:c.282C>T p.Tyr94= p.Y94= ENST00000241052 NM_001752.3 94 taC/taT 0 +CBFA2T2 UCSF GRCh37 20 32199107 32199107 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 168 51 229 0 ENST00000346541.3:c.413G>A p.Gly138Glu p.G138E ENST00000346541 NM_005093.3 138 gGg/gAg 0 +CCDC108 UCSF GRCh37 2 219888018 219888018 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 17 6 45 0 ENST00000341552.5:c.2731C>T p.Leu911= p.L911= ENST00000341552 NM_194302.3 911 Ctg/Ttg 0 +CCDC132 UCSF GRCh37 7 92979301 92979301 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 16 117 0 ENST00000305866.5:c.2419G>A p.Glu807Lys p.E807K ENST00000305866 NM_017667.3 807 Gaa/Aaa 0 +CCDC135 UCSF GRCh37 16 57764849 57764849 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 106 31 159 0 ENST00000360716.3:c.2398C>T p.Gln800Ter p.Q800* ENST00000360716 800 Cag/Tag 0 +CCDC86 UCSF GRCh37 11 60609982 60609982 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 135 28 164 0 ENST00000227520.5:c.385C>T p.Gln129Ter p.Q129* ENST00000227520 NM_024098.3 129 Cag/Tag 0 +CCDC97 UCSF GRCh37 19 41825651 41825651 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 52 16 76 0 ENST00000269967.3:c.675C>T p.Leu225= p.L225= ENST00000269967 NM_052848.1 225 ctC/ctT 0 +CCND2 UCSF GRCh37 12 4385225 4385225 + splice_region_variant,non_coding_transcript_exon_variant Splice_Region SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 143 24 143 0 ENST00000539135.1:n.126G>A p.X42_splice ENST00000539135 0 +CCNJ UCSF GRCh37 10 97816568 97816568 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 82 40 141 0 ENST00000265992.5:c.391G>A p.Glu131Lys p.E131K ENST00000265992 NM_019084.4 131 Gaa/Aaa 0 +CCT8 UCSF GRCh37 21 30439053 30439053 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 106 20 114 0 ENST00000286788.4:c.608G>A p.Arg203Lys p.R203K ENST00000286788 NM_006585.2 203 aGa/aAa 0 +CD163L1 UCSF GRCh37 12 7559158 7559158 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 251 61 322 0 ENST00000313599.3:c.1057C>T p.His353Tyr p.H353Y ENST00000313599 353 Cat/Tat 0 +CD1B UCSF GRCh37 1 158299756 158299756 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.006,1000g2011may_all_0.01772,snp132_rs62642467 P21_Rec Untested WXS Illumina HiSeq 354 95 446 0 ENST00000368168.3:c.493C>T p.Leu165= p.L165= ENST00000368168 NM_001764.2 165 Cta/Tta 0 +CD276 UCSF GRCh37 15 73995123 73995123 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 23 66 0 ENST00000318443.5:c.429G>A p.Ser143= p.S143= ENST00000318443 NM_001024736.1 143 tcG/tcA 0 +CDAN1 UCSF GRCh37 15 43023168 43023168 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 48 222 0 ENST00000356231.3:c.1962C>T p.Pro654= p.P654= ENST00000356231 NM_138477.2 654 ccC/ccT 0 +CDC16 UCSF GRCh37 13 115002355 115002355 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 42 18 95 0 ENST00000356221.3:c.185C>T p.Ser62Leu p.S62L ENST00000356221 62 tCa/tTa 0 +CDC40 UCSF GRCh37 6 110541060 110541060 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 37 158 0 ENST00000307731.1:c.1328G>A p.Arg443Lys p.R443K ENST00000307731 NM_015891.2 443 aGa/aAa 0 +CDC42EP1 UCSF GRCh37 22 37962634 37962634 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 21 106 0 ENST00000249014.4:c.278G>A p.Gly93Glu p.G93E ENST00000249014 NM_152243.2 93 gGg/gAg 0 +CDH11 UCSF GRCh37 16 64981800 64981800 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 180 50 266 0 ENST00000268603.4:c.2097G>A p.Glu699= p.E699= ENST00000268603 NM_001797.2 699 gaG/gaA 0 +CDH12 UCSF GRCh37 5 21752025 21752025 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 138 38 212 0 ENST00000382254.1:c.2206C>T p.Leu736= p.L736= ENST00000382254 NM_004061.3 736 Ctg/Ttg 0 +CDH23 UCSF GRCh37 10 73405665 73405665 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 80 28 200 0 ENST00000224721.6:c.1233G>A p.Gln411= p.Q411= ENST00000224721 NM_022124.5 411 caG/caA 0 +CDH23 UCSF GRCh37 10 73544108 73544108 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 66 29 160 0 ENST00000224721.6:c.5448G>A p.Arg1816= p.R1816= ENST00000224721 NM_022124.5 1816 cgG/cgA 0 +CDHR3 UCSF GRCh37 7 105672892 105672892 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 108 38 167 0 ENST00000317716.9:c.2407G>A p.Asp803Asn p.D803N ENST00000317716 NM_152750.4 803 Gat/Aat 0 +CDKN1B UCSF GRCh37 12 12870849 12870849 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 39 0 ENST00000228872.4:c.78del p.Ser27ArgfsTer15 p.S27Rfs*15 ENST00000228872 NM_004064.3 26 Ccc/cc 0 +CDKN2A UCSF GRCh37 9 21974770 21974770 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 12 0 ENST00000304494.5:c.57del p.Ala20ArgfsTer6 p.A20Rfs*6 ENST00000304494 NM_000077.4 19 gcC/gc 0 +CDON UCSF GRCh37 11 125851126 125851126 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 98 12 173 0 ENST00000392693.3:c.3094G>A p.Val1032Ile p.V1032I ENST00000392693 NM_001243597.1 1032 Gtt/Att 0 +CDX4 UCSF GRCh37 X 72667505 72667505 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 4 42 63 0 ENST00000373514.2:c.416C>T p.Thr139Met p.T139M ENST00000373514 NM_005193.1 139 aCg/aTg 0 +CELSR3 UCSF GRCh37 3 48696345 48696345 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 60 15 103 0 ENST00000164024.4:c.3723G>A p.Val1241= p.V1241= ENST00000164024 NM_001407.2 1241 gtG/gtA 0 +CENPF UCSF GRCh37 1 214819208 214819208 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 142 18 157 0 ENST00000366955.3:c.6295G>A p.Glu2099Lys p.E2099K ENST00000366955 NM_016343.3 2099 Gag/Aag 0 +CEP350 UCSF GRCh37 1 179961206 179961206 + missense_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 36 7 42 0 ENST00000367607.3:c.245A>T p.Tyr82Phe p.Y82F ENST00000367607 NM_014810.4 82 tAc/tTc 0 +CEP72 UCSF GRCh37 5 620366 620366 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 21 133 0 ENST00000264935.5:c.393C>T p.Leu131= p.L131= ENST00000264935 NM_018140.3 131 ctC/ctT 0 +CEP78 UCSF GRCh37 9 80880305 80880305 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 29 154 0 ENST00000424347.2:c.1643C>T p.Thr548Ile p.T548I ENST00000424347 548 aCa/aTa 0 +CETN2 UCSF GRCh37 X 151997217 151997217 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 40 26 85 0 ENST00000370277.3:c.293C>T p.Ser98Phe p.S98F ENST00000370277 NM_004344.1 98 tCt/tTt 0 +CFHR5 UCSF GRCh37 1 196965270 196965270 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 156 38 189 0 ENST00000256785.4:c.909G>A p.Met303Ile p.M303I ENST00000256785 303 atG/atA 0 +CHCHD7 UCSF GRCh37 8 57129925 57129925 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 52 13 63 0 ENST00000355315.3:c.189G>A p.Val63= p.V63= ENST00000355315 NM_001011671.1 63 gtG/gtA 0 +CHD6 UCSF GRCh37 20 40162013 40162013 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 173 52 209 0 ENST00000373233.3:c.230C>T p.Thr77Ile p.T77I ENST00000373233 NM_032221.4 77 aCa/aTa 0 +CHD9 UCSF GRCh37 16 53357969 53357969 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 312 46 394 0 ENST00000398510.3:c.7856C>T p.Thr2619Ile p.T2619I ENST00000398510 2619 aCt/aTt 0 +CHEK2 UCSF GRCh37 22 29085187 29085187 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 122 30 260 0 ENST00000328354.6:c.1478G>A p.Arg493Lys p.R493K ENST00000328354 NM_007194.3 493 aGa/aAa 0 +CHI3L1 UCSF GRCh37 1 203151876 203151876 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 17 114 0 ENST00000255409.3:c.570C>T p.Asp190= p.D190= ENST00000255409 NM_001276.2 190 gaC/gaT 0 +CHMP7 UCSF GRCh37 8 23114047 23114047 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 226 58 359 0 ENST00000313219.7:c.732G>A p.Leu244= p.L244= ENST00000313219 244 ctG/ctA 0 +CHRM5 UCSF GRCh37 15 34356140 34356140 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 216 48 319 0 ENST00000383263.5:c.1222C>G p.Pro408Ala p.P408A ENST00000383263 NM_012125.3 408 Cca/Gca 0 +CHRNA1 UCSF GRCh37 2 175619138 175619138 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 70 25 142 0 ENST00000261007.5:c.424G>A p.Asp142Asn p.D142N ENST00000261007 NM_001039523.2 142 Gat/Aat 0 +CHST9 UCSF GRCh37 18 24604085 24604085 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 29 16 43 0 ENST00000581714.1:c.197G>A p.Arg66Lys p.R66K ENST00000581714 66 aGa/aAa 0 +CLCNKA UCSF GRCh37 1 16355325 16355325 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 21 123 0 ENST00000331433.4:c.1038C>T p.His346= p.H346= ENST00000331433 346 caC/caT 0 +CLEC6A UCSF GRCh37 12 8618156 8618156 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 25 169 0 ENST00000382073.3:c.300G>A p.Trp100Ter p.W100* ENST00000382073 NM_001007033.1 100 tgG/tgA 0 +CLK2 UCSF GRCh37 1 155233756 155233756 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 48 187 0 ENST00000368361.4:c.1302C>T p.Asn434= p.N434= ENST00000368361 434 aaC/aaT 0 +CLSPN UCSF GRCh37 1 36230067 36230067 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 136 26 100 1 ENST00000318121.3:c.382G>A p.Val128Met p.V128M ENST00000318121 NM_022111.3 128 Gtg/Atg 0 +CLSTN3 UCSF GRCh37 12 7285717 7285717 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 59 15 82 0 ENST00000266546.6:c.162C>T p.Asp54= p.D54= ENST00000266546 NM_014718.3 54 gaC/gaT 0 +CMAS UCSF GRCh37 12 22218154 22218154 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 210 34 190 0 ENST00000229329.2:c.1214G>A p.Cys405Tyr p.C405Y ENST00000229329 NM_018686.4 405 tGc/tAc 0 +CMYA5 UCSF GRCh37 5 79025325 79025325 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 193 47 194 0 ENST00000446378.2:c.737G>A p.Gly246Glu p.G246E ENST00000446378 NM_153610.3 246 gGa/gAa 0 +CNGA1 UCSF GRCh37 4 47951873 47951873 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 74 21 89 0 ENST00000358519.4:c.276G>A p.Val92= p.V92= ENST00000358519 92 gtG/gtA 0 +CNPY4 UCSF GRCh37 7 99722496 99722496 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 46 217 0 ENST00000262932.3:c.732C>T p.Asp244= p.D244= ENST00000262932 NM_152755.1 244 gaC/gaT 0 +CNR2 UCSF GRCh37 1 24201575 24201575 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 107 27 151 0 ENST00000374472.4:c.533C>T p.Pro178Leu p.P178L ENST00000374472 NM_001841.2 178 cCc/cTc 0 +CNTN6 UCSF GRCh37 3 1444021 1444021 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 75 29 127 0 ENST00000350110.2:c.2837G>A p.Arg946Lys p.R946K ENST00000350110 NM_014461.2 946 aGa/aAa 0 +CNTNAP1 UCSF GRCh37 17 40849300 40849300 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 85 16 109 0 ENST00000264638.4:c.3483C>T p.Tyr1161= p.Y1161= ENST00000264638 NM_003632.2 1161 taC/taT 0 +COG8 UCSF GRCh37 16 69366747 69366747 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 127 34 191 0 ENST00000306875.4:c.1452G>A p.Glu484= p.E484= ENST00000306875 NM_032382.4 484 gaG/gaA 0 +COL10A1 UCSF GRCh37 6 116442735 116442735 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 37 5 82 0 ENST00000243222.4:c.544C>T p.Pro182Ser p.P182S ENST00000243222 NM_000493.3 182 Cct/Tct 0 +COL1A1 UCSF GRCh37 17 48273995 48273995 + missense_variant Missense_Mutation SNP C C T snp132_rs72645334 P21_Rec Untested WXS Illumina HiSeq 370 93 491 0 ENST00000225964.5:c.841G>A p.Gly281Ser p.G281S ENST00000225964 NM_000088.3 281 Ggt/Agt 0 +COL5A3 UCSF GRCh37 19 10108817 10108817 + synonymous_variant Silent SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 270 59 364 0 ENST00000264828.3:c.1119A>G p.Gly373= p.G373= ENST00000264828 NM_015719.3 373 ggA/ggG 0 +COL6A2 UCSF GRCh37 21 47544812 47544812 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 66 17 80 0 ENST00000300527.4:c.1748C>T p.Pro583Leu p.P583L ENST00000300527 NM_001849.3 583 cCc/cTc 0 +COL6A3 UCSF GRCh37 2 238303787 238303787 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 46 23 75 0 ENST00000295550.4:c.152G>A p.Gly51Glu p.G51E ENST00000295550 NM_004369.3 51 gGa/gAa 0 +COL6A3 UCSF GRCh37 2 238275523 238275523 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 106 38 214 0 ENST00000295550.4:c.5307G>A p.Arg1769= p.R1769= ENST00000295550 NM_004369.3 1769 agG/agA 0 +COL6A6 UCSF GRCh37 3 130286093 130286093 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 303 74 365 0 ENST00000358511.6:c.1830C>T p.Ile610= p.I610= ENST00000358511 NM_001102608.1 610 atC/atT 0 +COL6A6 UCSF GRCh37 3 130300508 130300508 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 365 97 443 0 ENST00000358511.6:c.3651C>T p.Ile1217= p.I1217= ENST00000358511 NM_001102608.1 1217 atC/atT 0 +COL9A1 UCSF GRCh37 6 70973001 70973001 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 17 3 29 0 ENST00000357250.6:c.1342-1G>A p.X448_splice ENST00000357250 NM_001851.4 0 +COL9A2 UCSF GRCh37 1 40777380 40777380 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 26 123 0 ENST00000372748.3:c.425C>T p.Pro142Leu p.P142L ENST00000372748 NM_001852.3 142 cCt/cTt 0 +COPA UCSF GRCh37 1 160281759 160281759 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 81 21 128 0 ENST00000241704.7:c.975C>T p.Ala325= p.A325= ENST00000241704 NM_004371.3 325 gcC/gcT 0 +COPB1 UCSF GRCh37 11 14510097 14510097 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 22 12 62 0 ENST00000249923.3:c.640G>A p.Asp214Asn p.D214N ENST00000249923 NM_016451.4 214 Gat/Aat 0 +COQ2 UCSF GRCh37 4 84191112 84191112 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 83 44 229 1 ENST00000311469.4:c.813G>A p.Trp271Ter p.W271* ENST00000311469 NM_015697.7 271 tgG/tgA 0 +CORO1A UCSF GRCh37 16 30199523 30199523 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 129 18 213 0 ENST00000219150.5:c.1018C>T p.Leu340= p.L340= ENST00000219150 NM_007074.3 340 Ctg/Ttg 0 +CP UCSF GRCh37 3 148899850 148899850 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 126 38 163 0 ENST00000264613.6:c.2496C>T p.Tyr832= p.Y832= ENST00000264613 NM_000096.3 832 taC/taT 0 +CPNE3 UCSF GRCh37 8 87540831 87540831 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 85 19 115 0 ENST00000198765.4:c.58G>T p.Asp20Tyr p.D20Y ENST00000198765 20 Gat/Tat 0 +CPNE3 UCSF GRCh37 8 87559997 87559997 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 42 6 40 0 ENST00000198765.4:c.878C>T p.Thr293Ile p.T293I ENST00000198765 293 aCt/aTt 0 +CPNE6 UCSF GRCh37 14 24546809 24546809 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 104 48 249 0 ENST00000397016.2:c.1544C>T p.Pro515Leu p.P515L ENST00000397016 NM_001280558.1 515 cCc/cTc 0 +CPNE9 UCSF GRCh37 3 9746480 9746480 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 25 4 29 0 ENST00000383832.3:c.156+1G>A p.X52_splice ENST00000383832 NM_153635.2 0 +CPT1A UCSF GRCh37 11 68540840 68540840 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 102 37 161 0 ENST00000265641.5:c.1633G>A p.Asp545Asn p.D545N ENST00000265641 NM_001876.3 545 Gat/Aat 0 +CRADD UCSF GRCh37 12 94244012 94244012 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 46 11 58 0 ENST00000332896.3:c.565G>A p.Val189Met p.V189M ENST00000332896 NM_003805.3 189 Gtg/Atg 0 +CREBBP UCSF GRCh37 16 3779333 3779333 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 14 5 24 0 ENST00000262367.5:c.5715C>T p.Pro1905= p.P1905= ENST00000262367 NM_004380.2 1905 ccC/ccT 0 +CRLF3 UCSF GRCh37 17 29112936 29112936 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 81 16 96 0 ENST00000324238.6:c.1072+1G>A p.X358_splice ENST00000324238 NM_015986.3 0 +CRMP1 UCSF GRCh37 4 5827243 5827243 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 105 27 145 0 ENST00000397890.2:c.1605C>T p.His535= p.H535= ENST00000397890 NM_001313.3 535 caC/caT 0 +CRTC1 UCSF GRCh37 19 18888034 18888034 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 262 100 327 0 ENST00000321949.8:c.1747G>A p.Gly583Arg p.G583R ENST00000321949 NM_015321.2 583 Ggg/Agg 0 +CSHL1 UCSF GRCh37 17 61987262 61987262 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 242 70 341 0 ENST00000309894.5:c.478G>A p.Glu160Lys p.E160K ENST00000309894 NM_022579.1 160 Gaa/Aaa 0 +CTDP1 UCSF GRCh37 18 77474755 77474755 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 13 5 25 0 ENST00000299543.7:c.1295G>A p.Gly432Asp p.G432D ENST00000299543 NM_001202504.1 432 gGt/gAt 0 +CTLA4 UCSF GRCh37 2 204736188 204736188 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 114 32 179 0 ENST00000302823.3:c.545C>T p.Thr182Ile p.T182I ENST00000302823 NM_005214.4 182 aCa/aTa 0 +CTNNA3 UCSF GRCh37 10 69281603 69281603 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 76 20 146 0 ENST00000433211.2:c.576G>A p.Gln192= p.Q192= ENST00000433211 NM_013266.2 192 caG/caA 0 +CTSL2 UCSF GRCh37 9 99799878 99799878 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 266 62 339 0 ENST00000259470.5:c.146G>A p.Arg49Lys p.R49K ENST00000259470 NM_001333.3 49 aGa/aAa 0 +CTTNBP2NL UCSF GRCh37 1 112991731 112991731 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 81 22 91 0 ENST00000271277.6:c.267G>A p.Gln89= p.Q89= ENST00000271277 NM_018704.2 89 caG/caA 0 +CTU2 UCSF GRCh37 16 88776418 88776418 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 122 31 274 0 ENST00000453996.2:c.216C>T p.Gly72= p.G72= ENST00000453996 NM_001012759.1 72 ggC/ggT 0 +CUL7 UCSF GRCh37 6 43005665 43005665 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 90 15 72 0 ENST00000265348.3:c.4858G>A p.Asp1620Asn p.D1620N ENST00000265348 1620 Gac/Aac 0 +CX3CL1 UCSF GRCh37 16 57416257 57416257 + synonymous_variant Silent SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 56 29 102 0 ENST00000006053.6:c.507C>A p.Leu169= p.L169= ENST00000006053 NM_002996.3 169 ctC/ctA 0 +CYB5D1 UCSF GRCh37 17 7762789 7762789 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 121 39 199 0 ENST00000332439.4:c.546G>A p.Gly182= p.G182= ENST00000332439 NM_144607.4 182 ggG/ggA 0 +CYFIP2 UCSF GRCh37 5 156747704 156747704 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 58 37 169 0 ENST00000521420.1:c.1487G>A p.Gly496Glu p.G496E ENST00000521420 496 gGa/gAa 0 +CYP26C1 UCSF GRCh37 10 94828367 94828367 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 17 10 37 0 ENST00000285949.5:c.1482G>A p.Thr494= p.T494= ENST00000285949 NM_183374.2 494 acG/acA 0 +CYTH2 UCSF GRCh37 19 48973630 48973630 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 157 53 231 0 ENST00000427476.1:c.40G>A p.Glu14Lys p.E14K ENST00000427476 NM_017457.5 14 Gag/Aag 0 +DACT1 UCSF GRCh37 14 59107525 59107525 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 152 56 243 0 ENST00000335867.4:c.417G>A p.Leu139= p.L139= ENST00000335867 139 ctG/ctA 0 +DBF4B UCSF GRCh37 17 42828469 42828469 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 167 59 280 0 ENST00000315005.3:c.1696C>T p.Pro566Ser p.P566S ENST00000315005 NM_145663.2 566 Ccc/Tcc 0 +DCHS1 UCSF GRCh37 11 6648774 6648774 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 8 117 0 ENST00000299441.3:c.5496G>A p.Gln1832= p.Q1832= ENST00000299441 NM_003737.2 1832 caG/caA 0 +DCHS1 UCSF GRCh37 11 6643673 6643673 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 11 46 0 ENST00000299441.3:c.9234C>T p.Asp3078= p.D3078= ENST00000299441 NM_003737.2 3078 gaC/gaT 0 +DDR1 UCSF GRCh37 6 30865957 30865957 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 204 27 145 0 ENST00000324771.8:c.2324G>A p.Gly775Glu p.G775E ENST00000324771 775 gGg/gAg 0 +DDX18 UCSF GRCh37 2 118586528 118586528 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 46 8 57 0 ENST00000263239.2:c.1639C>T p.Pro547Ser p.P547S ENST00000263239 NM_006773.3 547 Cca/Tca 0 +DDX49 UCSF GRCh37 19 19033453 19033453 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 29 141 0 ENST00000247003.4:c.676G>A p.Val226Met p.V226M ENST00000247003 NM_019070.4 226 Gtg/Atg 0 +DENND2D UCSF GRCh37 1 111740573 111740573 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 40 18 48 0 ENST00000357640.4:c.395G>A p.Ser132Asn p.S132N ENST00000357640 NM_024901.4 132 aGc/aAc 0 +DIDO1 UCSF GRCh37 20 61511428 61511428 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 209 52 314 0 ENST00000266070.4:c.5880G>A p.Arg1960= p.R1960= ENST00000266070 NM_033081.2 1960 agG/agA 0 +DLEC1 UCSF GRCh37 3 38125727 38125727 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 129 35 150 1 ENST00000308059.6:c.1252C>T p.Leu418= p.L418= ENST00000308059 418 Ctg/Ttg 0 +DLGAP4 UCSF GRCh37 20 35125306 35125306 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 22 155 0 ENST00000339266.5:c.1847C>T p.Thr616Ile p.T616I ENST00000339266 616 aCc/aTc 0 +DLL4 UCSF GRCh37 15 41229048 41229048 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 137 42 171 0 ENST00000249749.5:c.1863C>T p.Pro621= p.P621= ENST00000249749 NM_019074.3 621 ccC/ccT 0 +DMXL1 UCSF GRCh37 5 118469874 118469874 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 168 27 188 0 ENST00000311085.8:c.2254+1G>A p.X752_splice ENST00000311085 NM_005509.4 0 +DNAH11 UCSF GRCh37 7 21723468 21723468 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 253 109 475 1 ENST00000409508.3:c.5527C>T p.His1843Tyr p.H1843Y ENST00000409508 NM_001277115.1 1843 Cac/Tac 0 +DNAH9 UCSF GRCh37 17 11583146 11583146 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 154 46 251 1 ENST00000262442.4:c.3426C>T p.Phe1142= p.F1142= ENST00000262442 NM_001372.3 1142 ttC/ttT 0 +DNAH9 UCSF GRCh37 17 11795177 11795177 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 187 39 242 1 ENST00000262442.4:c.11196C>T p.Asp3732= p.D3732= ENST00000262442 NM_001372.3 3732 gaC/gaT 0 +DNAJC13 UCSF GRCh37 3 132203503 132203503 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 133 26 142 0 ENST00000260818.6:c.3254C>T p.Pro1085Leu p.P1085L ENST00000260818 NM_015268.3 1085 cCc/cTc 0 +DNAJC13 UCSF GRCh37 3 132172971 132172971 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 86 12 85 0 ENST00000260818.6:c.902G>A p.Gly301Glu p.G301E ENST00000260818 NM_015268.3 301 gGg/gAg 0 +DNAJC14 UCSF GRCh37 12 56221696 56221696 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 103 46 214 0 ENST00000317269.3:c.747G>A p.Gln249= p.Q249= ENST00000317269 NM_032364.5 249 caG/caA 0 +DNPEP UCSF GRCh37 2 220251054 220251054 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 50 246 0 ENST00000273075.4:c.413C>T p.Thr138Ile p.T138I ENST00000273075 NM_012100.2 138 aCc/aTc 0 +DOCK5 UCSF GRCh37 8 25174587 25174587 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 345 42 467 1 ENST00000276440.7:c.1383G>A p.Lys461= p.K461= ENST00000276440 NM_024940.6 461 aaG/aaA 0 +DPCD UCSF GRCh37 10 103361091 103361091 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 95 40 221 0 ENST00000370151.4:c.402G>A p.Lys134= p.K134= ENST00000370151 NM_015448.1 134 aaG/aaA 0 +DPEP2 UCSF GRCh37 16 68026929 68026929 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 11 6 31 0 ENST00000393847.1:c.187A>G p.Thr63Ala p.T63A ENST00000393847 NM_022355.3 63 Aca/Gca 0 +DPP8 UCSF GRCh37 15 65756199 65756199 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 72 16 89 0 ENST00000341861.5:c.1919G>A p.Ser640Asn p.S640N ENST00000341861 NM_197960.2 640 aGt/aAt 0 +DPP8 UCSF GRCh37 15 65771336 65771336 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 64 24 63 0 ENST00000341861.5:c.1386G>A p.Glu462= p.E462= ENST00000341861 NM_197960.2 462 gaG/gaA 0 +DPP9 UCSF GRCh37 19 4697580 4697580 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 37 31 85 0 ENST00000598800.1:c.1071G>A p.Trp357Ter p.W357* ENST00000598800 357 tgG/tgA 0 +DPYSL5 UCSF GRCh37 2 27165609 27165609 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 69 24 126 0 ENST00000288699.6:c.1431G>A p.Gln477= p.Q477= ENST00000288699 NM_001253724.1 477 caG/caA 0 +DSCAM UCSF GRCh37 21 41668075 41668075 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 133 27 138 0 ENST00000400454.1:c.2089C>T p.Arg697Trp p.R697W ENST00000400454 NM_001271534.1 697 Cgg/Tgg 0 +DST UCSF GRCh37 6 56483139 56483139 + intron_variant Intron SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 164 24 119 0 ENST00000244364.6:c.3319-3857G>A *1107* ENST00000244364 NM_015548.4 0 +DST UCSF GRCh37 6 56438626 56438626 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 333 39 281 0 ENST00000244364.6:c.5218C>T p.Leu1740Phe p.L1740F ENST00000244364 NM_015548.4 1740 Ctc/Ttc 0 +DTNA UCSF GRCh37 18 32462088 32462088 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 20 137 0 ENST00000399113.3:c.2137G>A p.Asp713Asn p.D713N ENST00000399113 713 Gac/Aac 0 +DUOX2 UCSF GRCh37 15 45386450 45386450 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 84 25 103 0 ENST00000603300.1:c.4545C>T p.Phe1515= p.F1515= ENST00000603300 NM_014080.4 1515 ttC/ttT 0 +DYTN UCSF GRCh37 2 207569614 207569614 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 51 250 0 ENST00000452335.2:c.436C>T p.Arg146Cys p.R146C ENST00000452335 NM_001093730.1 146 Cgc/Tgc 0 +EBF4 UCSF GRCh37 20 2690257 2690257 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 18 3 34 0 ENST00000609451.1:c.526G>A p.Glu176Lys p.E176K ENST00000609451 176 Gag/Aag 0 +EDC4 UCSF GRCh37 16 67915601 67915601 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 25 135 0 ENST00000358933.5:c.2857C>T p.Leu953= p.L953= ENST00000358933 NM_014329.4 953 Cta/Tta 0 +EEF1A1 UCSF GRCh37 6 74228138 74228138 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 52 33 288 0 ENST00000309268.6:c.968G>A p.Gly323Asp p.G323D ENST00000309268 323 gGc/gAc 0 +EFR3A UCSF GRCh37 8 132966207 132966207 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 150 29 126 0 ENST00000254624.5:c.631G>A p.Val211Ile p.V211I ENST00000254624 NM_015137.4 211 Gtt/Att 0 +EHD1 UCSF GRCh37 11 64645795 64645795 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 147 48 248 0 ENST00000320631.3:c.142C>T p.Pro48Ser p.P48S ENST00000320631 NM_006795.2 48 Ccc/Tcc 0 +EHMT2 UCSF GRCh37 6 31864468 31864468 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 199 29 135 0 ENST00000375537.4:c.243C>T p.Thr81= p.T81= ENST00000375537 NM_006709.3 81 acC/acT 0 +EIF2AK2 UCSF GRCh37 2 37374877 37374877 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 155 51 268 0 ENST00000233057.4:c.73C>T p.Leu25Phe p.L25F ENST00000233057 NM_001135651.2 25 Ctt/Ttt 0 +EIF2AK3 UCSF GRCh37 2 88874467 88874467 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 188 45 273 0 ENST00000303236.3:c.2534G>A p.Ser845Asn p.S845N ENST00000303236 NM_004836.5 845 aGc/aAc 0 +EIF2C1 UCSF GRCh37 1 36360759 36360759 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 135 23 199 0 ENST00000373204.4:c.909G>A p.Glu303= p.E303= ENST00000373204 NM_012199.2 303 gaG/gaA 0 +EIF2D UCSF GRCh37 1 206772907 206772907 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 141 28 179 0 ENST00000271764.2:c.1112G>A p.Ser371Asn p.S371N ENST00000271764 NM_006893.2 371 aGc/aAc 0 +ELANE UCSF GRCh37 19 855770 855770 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 31 100 0 ENST00000263621.1:c.573G>A p.Arg191= p.R191= ENST00000263621 NM_001972.2 191 agG/agA 0 +ELL UCSF GRCh37 19 18572590 18572590 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 127 20 142 0 ENST00000262809.4:c.542C>T p.Pro181Leu p.P181L ENST00000262809 NM_006532.3 181 cCc/cTc 0 +ELMO3 UCSF GRCh37 16 67236151 67236151 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 168 56 291 0 ENST00000393997.2:c.1384G>A p.Val462Met p.V462M ENST00000393997 NM_024712.3 462 Gtg/Atg 0 +EME1 UCSF GRCh37 17 48456458 48456458 + intron_variant Intron SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 118 30 151 1 ENST00000338165.4:c.1113-10C>T *371* ENST00000338165 NM_152463.2 0 +EMR1 UCSF GRCh37 19 6937382 6937382 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 102 43 194 1 ENST00000312053.4:c.2510G>A p.Gly837Glu p.G837E ENST00000312053 NM_001974.4 837 gGg/gAg 0 +ENTHD1 UCSF GRCh37 22 40140178 40140178 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 112 28 132 0 ENST00000325157.6:c.1330C>T p.Pro444Ser p.P444S ENST00000325157 NM_152512.3 444 Cct/Tct 0 +EP400 UCSF GRCh37 12 132529870 132529870 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 54 16 98 0 ENST00000389561.2:c.6791G>A p.Gly2264Asp p.G2264D ENST00000389561 NM_015409.4 2264 gGc/gAc 0 +EPB41L4B UCSF GRCh37 9 111947801 111947801 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 55 11 72 0 ENST00000374566.3:c.2386G>A p.Val796Ile p.V796I ENST00000374566 NM_019114.3 796 Gtt/Att 0 +EPC2 UCSF GRCh37 2 149447906 149447906 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 282 59 375 0 ENST00000258484.6:c.277G>A p.Glu93Lys p.E93K ENST00000258484 NM_015630.3 93 Gag/Aag 0 +EPHA6 UCSF GRCh37 3 97198182 97198182 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 63 10 96 0 ENST00000389672.5:c.2048G>A p.Arg683Lys p.R683K ENST00000389672 NM_001080448.2 683 aGa/aAa 0 +EPHB3 UCSF GRCh37 3 184293762 184293762 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 51 222 0 ENST00000330394.2:c.1001G>A p.Ser334Asn p.S334N ENST00000330394 NM_004443.3 334 aGt/aAt 0 +EPRS UCSF GRCh37 1 220160503 220160503 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 108 30 130 0 ENST00000366923.3:c.3019G>A p.Gly1007Arg p.G1007R ENST00000366923 NM_004446.2 1007 Ggg/Agg 0 +ERCC6L UCSF GRCh37 X 71427075 71427075 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 80 44 126 0 ENST00000334463.3:c.1542G>A p.Leu514= p.L514= ENST00000334463 NM_017669.2 514 ttG/ttA 0 +ERCC8 UCSF GRCh37 5 60240799 60240799 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 153 22 171 0 ENST00000265038.5:c.37G>A p.Glu13Lys p.E13K ENST00000265038 NM_000082.3 13 Gag/Aag 0 +ESPL1 UCSF GRCh37 12 53663436 53663436 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 209 88 413 0 ENST00000257934.4:c.710G>A p.Gly237Glu p.G237E ENST00000257934 NM_012291.4 237 gGg/gAg 0 +ESRP1 UCSF GRCh37 8 95654212 95654212 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 217 43 206 0 ENST00000433389.2:c.161G>A p.Arg54Lys p.R54K ENST00000433389 NM_001034915.2 54 aGa/aAa 0 +EVC2 UCSF GRCh37 4 5624425 5624425 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 48 37 99 0 ENST00000344408.5:c.2340C>T p.His780= p.H780= ENST00000344408 NM_147127.4 780 caC/caT 0 +EYA3 UCSF GRCh37 1 28384522 28384522 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 139 36 163 0 ENST00000373871.3:c.16G>A p.Asp6Asn p.D6N ENST00000373871 6 Gat/Aat 0 +FAAH UCSF GRCh37 1 46871454 46871454 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 61 23 105 0 ENST00000243167.8:c.773G>A p.Gly258Glu p.G258E ENST00000243167 NM_001441.2 258 gGg/gAg 0 +FAF2 UCSF GRCh37 5 175906208 175906208 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 25 133 0 ENST00000261942.6:c.83C>T p.Ser28Phe p.S28F ENST00000261942 NM_014613.2 28 tCt/tTt 0 +FAM109B UCSF GRCh37 22 42474031 42474031 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 16 7 15 0 ENST00000321753.3:c.734G>A p.Arg245Lys p.R245K ENST00000321753 NM_001002034.2 245 aGg/aAg 0 +FAM110B UCSF GRCh37 8 59059817 59059817 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 81 17 131 0 ENST00000361488.3:c.1028C>T p.Ser343Phe p.S343F ENST00000361488 NM_147189.2 343 tCt/tTt 0 +FAM117B UCSF GRCh37 2 203622117 203622117 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 77 14 138 0 ENST00000392238.2:c.1286G>A p.Ser429Asn p.S429N ENST00000392238 429 aGt/aAt 0 +FAM120A UCSF GRCh37 9 96320950 96320950 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 112 36 144 0 ENST00000277165.6:c.2756G>A p.Cys919Tyr p.C919Y ENST00000277165 NM_014612.3 919 tGc/tAc 0 +FAM120AOS UCSF GRCh37 9 96214878 96214878 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 36 13 54 0 ENST00000375412.5:c.114C>T p.Asp38= p.D38= ENST00000375412 NM_198841.2 38 gaC/gaT 0 +FAM153A UCSF GRCh37 5 177166124 177166124 + synonymous_variant,NMD_transcript_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 60 9 136 1 ENST00000360669.6:c.321C>T p.Thr107= p.T107= ENST00000360669 107 acC/acT 0 +FAM179B UCSF GRCh37 14 45432574 45432574 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 33 148 0 ENST00000361577.3:c.950G>A p.Ser317Asn p.S317N ENST00000361577 NM_015091.2 317 aGt/aAt 0 +FAM184B UCSF GRCh37 4 17636702 17636702 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 110 29 129 0 ENST00000265018.3:c.2819G>A p.Ser940Asn p.S940N ENST00000265018 NM_015688.1 940 aGt/aAt 0 +FAM208B UCSF GRCh37 10 5789811 5789811 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 151 22 146 0 ENST00000328090.5:c.4427C>T p.Ser1476Phe p.S1476F ENST00000328090 NM_017782.4 1476 tCt/tTt 0 +FAM21B UCSF GRCh37 10 47911067 47911067 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 28 5 73 0 ENST00000358474.5:c.935C>T p.Pro312Leu p.P312L ENST00000358474 NM_018232.1 312 cCt/cTt 0 +FAM40A UCSF GRCh37 1 110582130 110582130 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 12 6 37 0 ENST00000369795.3:c.574G>A p.Glu192Lys p.E192K ENST00000369795 NM_033088.3 192 Gaa/Aaa 0 +FAM40B UCSF GRCh37 7 129096376 129096376 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 86 33 189 0 ENST00000249344.2:c.931G>A p.Val311Met p.V311M ENST00000249344 NM_020704.2 311 Gtg/Atg 0 +FAM47C UCSF GRCh37 X 37026847 37026847 + stop_gained Nonsense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 82 56 152 0 ENST00000358047.3:c.364G>T p.Glu122Ter p.E122* ENST00000358047 NM_001013736.2 122 Gaa/Taa 0 +FAM76A UCSF GRCh37 1 28081740 28081740 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 178 48 232 0 ENST00000373954.6:c.634A>G p.Thr212Ala p.T212A ENST00000373954 NM_152660.2 212 Act/Gct 0 +FAM96A UCSF GRCh37 15 64365200 64365200 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 136 50 144 0 ENST00000300030.3:c.413G>A p.Arg138Gln p.R138Q ENST00000300030 NM_032231.4 138 cGa/cAa 0 +FAN1 UCSF GRCh37 15 31221558 31221558 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 173 38 222 0 ENST00000362065.4:c.2745C>T p.Ser915= p.S915= ENST00000362065 NM_014967.4 915 tcC/tcT 0 +FANCM UCSF GRCh37 14 45668044 45668044 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 86 34 122 0 ENST00000267430.5:c.5914G>A p.Ala1972Thr p.A1972T ENST00000267430 NM_020937.2 1972 Gca/Aca 0 +FAT1 UCSF GRCh37 4 187557930 187557930 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 332 173 707 1 ENST00000441802.2:c.3781G>A p.Asp1261Asn p.D1261N ENST00000441802 NM_005245.3 1261 Gac/Aac 0 +FBXL18 UCSF GRCh37 7 5530973 5530973 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 24 8 39 0 ENST00000382368.3:c.1889C>T p.Pro630Leu p.P630L ENST00000382368 NM_024963.4 630 cCc/cTc 0 +FBXO5 UCSF GRCh37 6 153296649 153296649 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 85 45 181 0 ENST00000229758.3:c.211C>T p.Leu71= p.L71= ENST00000229758 NM_012177.3 71 Cta/Tta 0 +FCGR2A UCSF GRCh37 1 161483691 161483691 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 249 57 355 1 ENST00000271450.6:c.749C>T p.Ser250Phe p.S250F ENST00000271450 NM_021642.3 250 tCc/tTc 0 +FCGR3B UCSF GRCh37 1 161600921 161600921 + 5_prime_UTR_variant 5'UTR SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 157 43 259 0 ENST00000294800.3:c.-37G>A *13* ENST00000294800 NM_001271035.1 0 +FEM1C UCSF GRCh37 5 114879155 114879155 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 111 35 130 0 ENST00000274457.3:c.36G>A p.Arg12= p.R12= ENST00000274457 NM_020177.2 12 cgG/cgA 0 +FERMT3 UCSF GRCh37 11 63978216 63978216 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 266 60 368 0 ENST00000279227.5:c.294G>A p.Arg98= p.R98= ENST00000279227 NM_178443.2 98 cgG/cgA 0 +FGFR2 UCSF GRCh37 10 123278254 123278254 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 37 24 143 0 ENST00000358487.5:c.939+1239C>T *313* ENST00000358487 NM_000141.4 0 +FILIP1L UCSF GRCh37 3 99643078 99643078 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 239 71 349 0 ENST00000354552.3:c.601G>A p.Glu201Lys p.E201K ENST00000354552 NM_182909.2 201 Gaa/Aaa 0 +FIP1L1 UCSF GRCh37 4 54319248 54319249 + frameshift_variant Frame_Shift_Del DEL AG AG - 1000g2010nov_all P21_Rec Untested WXS Illumina HiSeq 20 0 ENST00000337488.6:c.1459_1460delAG p.Arg487GlyfsTer3 p.R487Gfs*3 ENST00000337488 NM_030917.3 483 AGa/a 0 +FKBP10 UCSF GRCh37 17 39974720 39974720 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 57 19 96 0 ENST00000321562.4:c.668C>T p.Pro223Leu p.P223L ENST00000321562 NM_021939.3 223 cCt/cTt 0 +FLG UCSF GRCh37 1 152280250 152280250 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 545 153 995 0 ENST00000368799.1:c.7112G>A p.Ser2371Asn p.S2371N ENST00000368799 NM_002016.1 2371 aGt/aAt 0 +FLG UCSF GRCh37 1 152287016 152287016 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 175 31 196 0 ENST00000368799.1:c.346G>A p.Glu116Lys p.E116K ENST00000368799 NM_002016.1 116 Gaa/Aaa 0 +FLNB UCSF GRCh37 3 58064451 58064451 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 27 3 29 0 ENST00000295956.4:c.549C>T p.Cys183= p.C183= ENST00000295956 NM_001457.3 183 tgC/tgT 0 +FLT1 UCSF GRCh37 13 29012374 29012374 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 30 5 86 0 ENST00000282397.4:c.497C>T p.Thr166Ile p.T166I ENST00000282397 NM_002019.4 166 aCt/aTt 0 +FMN2 UCSF GRCh37 1 240370916 240370916 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 60 27 118 1 ENST00000319653.9:c.2804C>T p.Pro935Leu p.P935L ENST00000319653 NM_020066.4 935 cCc/cTc 0 +FMO1 UCSF GRCh37 1 171254589 171254589 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 164 39 167 0 ENST00000354841.4:c.1505G>A p.Arg502Gln p.R502Q ENST00000354841 NM_001282692.1 502 cGa/cAa 0 +FOXJ3 UCSF GRCh37 1 42657376 42657376 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 184 24 286 0 ENST00000361346.1:c.949C>T p.Pro317Ser p.P317S ENST00000361346 NM_014947.4 317 Cct/Tct 0 +FPGT UCSF GRCh37 1 74671005 74671005 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 44 175 0 ENST00000609362.1:c.1274G>A p.Gly425Glu p.G425E ENST00000609362 425 gGg/gAg 0 +FRAS1 UCSF GRCh37 4 79430074 79430074 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 71 44 216 0 ENST00000264895.6:c.9694G>A p.Val3232Met p.V3232M ENST00000264895 NM_025074.6 3232 Gtg/Atg 0 +FSIP2 UCSF GRCh37 2 186670828 186670828 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 115 32 204 0 ENST00000424728.1:c.16795G>C p.Val5599Leu p.V5599L ENST00000424728 5599 Gta/Cta 0 +FTSJD1 UCSF GRCh37 16 71318473 71318473 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 105 31 118 0 ENST00000338099.5:c.1351G>A p.Glu451Lys p.E451K ENST00000338099 451 Gaa/Aaa 0 +FYTTD1 UCSF GRCh37 3 197482706 197482706 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 108 23 221 0 ENST00000241502.4:c.104-591G>A *35* ENST00000241502 NM_032288.6 0 +GABRA4 UCSF GRCh37 4 46979087 46979087 + missense_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 30 4 46 0 ENST00000264318.3:c.568T>A p.Phe190Ile p.F190I ENST00000264318 NM_000809.3 190 Ttc/Atc 0 +GABRG3 UCSF GRCh37 15 27765224 27765224 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 35 147 0 ENST00000333743.6:c.819G>A p.Val273= p.V273= ENST00000333743 NM_033223.4 273 gtG/gtA 0 +GADD45B UCSF GRCh37 19 2477114 2477114 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 69 15 95 0 ENST00000215631.4:c.234C>T p.Ile78= p.I78= ENST00000215631 NM_015675.3 78 atC/atT 0 +GALNT8 UCSF GRCh37 12 4853683 4853683 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 22 107 0 ENST00000252318.2:c.677G>A p.Gly226Glu p.G226E ENST00000252318 NM_017417.1 226 gGa/gAa 0 +GALNTL1 UCSF GRCh37 14 69799836 69799836 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 51 18 105 0 ENST00000337827.4:c.813G>A p.Gln271= p.Q271= ENST00000337827 NM_020692.2 271 caG/caA 0 +GATA2 UCSF GRCh37 3 128204813 128204813 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 45 9 76 0 ENST00000341105.2:c.628G>A p.Gly210Ser p.G210S ENST00000341105 NM_032638.4 210 Ggc/Agc 0 +GBA UCSF GRCh37 1 155204985 155204985 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 186 56 305 0 ENST00000327247.5:c.1505+1G>A p.X502_splice ENST00000327247 NM_001005742.2 0 +GBGT1 UCSF GRCh37 9 136030687 136030687 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 44 9 67 0 ENST00000372040.3:c.237G>A p.Leu79= p.L79= ENST00000372040 79 ctG/ctA 0 +GGA1 UCSF GRCh37 22 38019349 38019349 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 262 67 371 0 ENST00000343632.4:c.625G>A p.Glu209Lys p.E209K ENST00000343632 NM_013365.4 209 Gag/Aag 0 +GHRHR UCSF GRCh37 7 31008546 31008546 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 69 21 117 0 ENST00000326139.2:c.155C>T p.Thr52Ile p.T52I ENST00000326139 NM_000823.3 52 aCc/aTc 0 +GIPC3 UCSF GRCh37 19 3586840 3586840 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 57 14 99 0 ENST00000322315.5:c.440G>A p.Arg147Gln p.R147Q ENST00000322315 NM_133261.2 147 cGg/cAg 0 +GJA4 UCSF GRCh37 1 35260362 35260362 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 18 170 0 ENST00000342280.4:c.548C>T p.Pro183Leu p.P183L ENST00000342280 NM_002060.2 183 cCc/cTc 0 +GLG1 UCSF GRCh37 16 74542750 74542750 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 66 9 86 0 ENST00000422840.2:c.545C>T p.Ser182Phe p.S182F ENST00000422840 NM_001145667.1 182 tCt/tTt 0 +GLI3 UCSF GRCh37 7 42005317 42005317 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 198 24 316 0 ENST00000395925.3:c.3354C>T p.Asp1118= p.D1118= ENST00000395925 NM_000168.5 1118 gaC/gaT 0 +GLIPR1 UCSF GRCh37 12 75874799 75874799 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 38 154 0 ENST00000266659.3:c.139G>A p.Glu47Lys p.E47K ENST00000266659 NM_006851.2 47 Gag/Aag 0 +GMCL1 UCSF GRCh37 2 70096865 70096865 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 24 134 0 ENST00000282570.3:c.1233G>A p.Trp411Ter p.W411* ENST00000282570 NM_178439.3 411 tgG/tgA 0 +GMIP UCSF GRCh37 19 19745726 19745726 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 165 74 182 0 ENST00000203556.4:c.1762G>A p.Val588Ile p.V588I ENST00000203556 NM_016573.2 588 Gtc/Atc 0 +GMIP UCSF GRCh37 19 19740773 19740773 + stop_retained_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 23 4 24 0 ENST00000203556.4:c.2912G>A p.Ter971= p.*971= ENST00000203556 NM_016573.2 971 tGa/tAa 0 +GNAI2 UCSF GRCh37 3 50290583 50290583 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 192 24 289 0 ENST00000313601.6:c.431C>T p.Ser144Leu p.S144L ENST00000313601 NM_002070.2 144 tCa/tTa 0 +GNL3L UCSF GRCh37 X 54569664 54569664 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 24 5 53 0 ENST00000336470.4:c.415C>T p.Leu139= p.L139= ENST00000336470 NM_019067.5 139 Ctg/Ttg 0 +GPC1 UCSF GRCh37 2 241401873 241401873 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 43 9 43 0 ENST00000264039.2:c.591G>A p.Glu197= p.E197= ENST00000264039 NM_002081.2 197 gaG/gaA 0 +GPER UCSF GRCh37 7 1131933 1131933 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 83 40 169 0 ENST00000297469.3:c.569T>C p.Leu190Pro p.L190P ENST00000297469 NM_001505.2 190 cTg/cCg 0 +GPLD1 UCSF GRCh37 6 24475433 24475433 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 138 18 154 0 ENST00000230036.1:c.357G>A p.Leu119= p.L119= ENST00000230036 NM_001503.3 119 ttG/ttA 0 +GPR111 UCSF GRCh37 6 47649587 47649587 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 437 53 322 0 ENST00000296862.1:c.1292C>T p.Ser431Phe p.S431F ENST00000296862 431 tCt/tTt 0 +GPR112 UCSF GRCh37 X 135432388 135432388 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 66 57 130 0 ENST00000370652.1:c.6523C>T p.Leu2175= p.L2175= ENST00000370652 2175 Ctg/Ttg 0 +GPR114 UCSF GRCh37 16 57600590 57600590 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 37 214 0 ENST00000340339.4:c.626G>A p.Cys209Tyr p.C209Y ENST00000340339 NM_153837.1 209 tGt/tAt 0 +GPR125 UCSF GRCh37 4 22390463 22390463 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 141 24 138 0 ENST00000334304.5:c.2831G>A p.Arg944Lys p.R944K ENST00000334304 NM_145290.3 944 aGa/aAa 0 +GPR125 UCSF GRCh37 4 22389518 22389518 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 159 34 171 0 ENST00000334304.5:c.3776C>T p.Thr1259Ile p.T1259I ENST00000334304 NM_145290.3 1259 aCc/aTc 0 +GPR15 UCSF GRCh37 3 98251207 98251207 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 116 34 174 0 ENST00000284311.3:c.330C>T p.Ser110= p.S110= ENST00000284311 NM_005290.2 110 tcC/tcT 0 +GPR155 UCSF GRCh37 2 175335141 175335141 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 55 17 101 0 ENST00000295500.4:c.1003C>T p.Gln335Ter p.Q335* ENST00000295500 NM_001033045.3 335 Caa/Taa 0 +GRIN3A UCSF GRCh37 9 104432882 104432882 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 114 30 167 0 ENST00000361820.3:c.1812G>A p.Lys604= p.K604= ENST00000361820 NM_133445.2 604 aaG/aaA 0 +GSTA5 UCSF GRCh37 6 52701042 52701042 + synonymous_variant Silent SNP C C T snp132_rs61735553 P21_Rec Untested WXS Illumina HiSeq 503 67 463 0 ENST00000284562.2:c.264G>A p.Glu88= p.E88= ENST00000284562 NM_153699.1 88 gaG/gaA 0 +GTF2F1 UCSF GRCh37 19 6380431 6380431 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 326 83 504 1 ENST00000394456.5:c.1415A>G p.Asp472Gly p.D472G ENST00000394456 NM_002096.2 472 gAc/gGc 0 +GTPBP2 UCSF GRCh37 6 43596768 43596768 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 9 28 0 ENST00000307126.5:c.132G>A p.Lys44= p.K44= ENST00000307126 NM_019096.3 44 aaG/aaA 0 +GTPBP4 UCSF GRCh37 10 1054927 1054927 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 116 42 180 0 ENST00000360803.4:c.1143G>A p.Val381= p.V381= ENST00000360803 NM_012341.2 381 gtG/gtA 0 +GULP1 UCSF GRCh37 2 189405948 189405948 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 71 37 124 0 ENST00000359135.3:c.302G>A p.Cys101Tyr p.C101Y ENST00000359135 101 tGt/tAt 0 +GZF1 UCSF GRCh37 20 23351007 23351007 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 148 27 202 0 ENST00000338121.5:c.2065G>A p.Glu689Lys p.E689K ENST00000338121 689 Gag/Aag 0 +GZF1 UCSF GRCh37 20 23346133 23346133 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 167 58 341 0 ENST00000338121.5:c.1113C>T p.His371= p.H371= ENST00000338121 371 caC/caT 0 +H2AFY UCSF GRCh37 5 134670722 134670722 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 148 48 206 0 ENST00000510038.1:c.1063G>A p.Asp355Asn p.D355N ENST00000510038 355 Gac/Aac 0 +HAUS1 UCSF GRCh37 18 43702472 43702472 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 90 24 140 0 ENST00000282058.6:c.516G>A p.Arg172= p.R172= ENST00000282058 NM_138443.3 172 agG/agA 0 +HAUS5 UCSF GRCh37 19 36113550 36113550 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 83 17 80 0 ENST00000203166.5:c.1699C>T p.Leu567= p.L567= ENST00000203166 NM_015302.1 567 Ctg/Ttg 0 +HAUS8 UCSF GRCh37 19 17160698 17160698 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 231 59 331 0 ENST00000253669.5:c.1218G>A p.Gly406= p.G406= ENST00000253669 406 ggG/ggA 0 +HEATR1 UCSF GRCh37 1 236722401 236722401 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 91 20 112 0 ENST00000366582.3:c.4805C>T p.Pro1602Leu p.P1602L ENST00000366582 NM_018072.5 1602 cCt/cTt 0 +HEATR5A UCSF GRCh37 14 31813262 31813262 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 37 169 0 ENST00000389961.3:c.3050C>T p.Thr1017Ile p.T1017I ENST00000389961 1017 aCt/aTt 0 +HEATR5B UCSF GRCh37 2 37302778 37302778 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 105 33 177 0 ENST00000233099.5:c.448-1G>A p.X150_splice ENST00000233099 NM_019024.1 0 +HECW2 UCSF GRCh37 2 197184437 197184437 + stop_gained Nonsense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 95 44 197 0 ENST00000260983.3:c.1177G>T p.Glu393Ter p.E393* ENST00000260983 NM_020760.1 393 Gaa/Taa 0 +HERC1 UCSF GRCh37 15 63964892 63964892 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 130 23 144 1 ENST00000443617.2:c.7848G>A p.Glu2616= p.E2616= ENST00000443617 NM_003922.3 2616 gaG/gaA 0 +HERC2 UCSF GRCh37 15 28408402 28408402 + synonymous_variant Silent SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 115 17 165 0 ENST00000261609.7:c.10584T>C p.Gly3528= p.G3528= ENST00000261609 NM_004667.5 3528 ggT/ggC 0 +HERC3 UCSF GRCh37 4 89583686 89583686 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 47 39 111 0 ENST00000264345.3:c.1251C>T p.His417= p.H417= ENST00000264345 417 caC/caT 0 +HGS UCSF GRCh37 17 79663016 79663016 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 59 18 101 0 ENST00000329138.4:c.1380G>A p.Leu460= p.L460= ENST00000329138 NM_004712.4 460 ctG/ctA 0 +HHIPL2 UCSF GRCh37 1 222721267 222721267 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 46 24 83 0 ENST00000343410.6:c.120G>A p.Gln40= p.Q40= ENST00000343410 NM_024746.3 40 caG/caA 0 +HIBADH UCSF GRCh37 7 27582634 27582634 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 47 22 83 0 ENST00000265395.2:c.570G>A p.Gly190= p.G190= ENST00000265395 NM_152740.3 190 ggG/ggA 0 +HINFP UCSF GRCh37 11 119001584 119001584 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 104 57 318 0 ENST00000350777.2:c.331C>T p.Pro111Ser p.P111S ENST00000350777 NM_198971.2 111 Ccc/Tcc 0 +HIPK1 UCSF GRCh37 1 114516014 114516014 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 243 66 329 0 ENST00000369558.1:c.3513C>T p.Ala1171= p.A1171= ENST00000369558 1171 gcC/gcT 0 +HIST1H2AH UCSF GRCh37 6 27115070 27115070 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 235 193 280 0 ENST00000377459.1:c.163G>C p.Val55Leu p.V55L ENST00000377459 NM_080596.2 55 Gtg/Ctg 0 +HK3 UCSF GRCh37 5 176314586 176314586 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 26 12 88 0 ENST00000292432.5:c.1466C>T p.Pro489Leu p.P489L ENST00000292432 NM_002115.2 489 cCa/cTa 0 +HLA-DQA2 UCSF GRCh37 6 32713057 32713057 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 499 67 352 0 ENST00000374940.3:c.204C>T p.Val68= p.V68= ENST00000374940 NM_020056.4 68 gtC/gtT 0 +HMOX2 UCSF GRCh37 16 4556969 4556969 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 339 50 568 0 ENST00000219700.6:c.160G>A p.Val54Ile p.V54I ENST00000219700 NM_001286268.1 54 Gtc/Atc 0 +HNRNPH1 UCSF GRCh37 5 179046349 179046349 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 129 74 331 0 ENST00000356731.5:c.457G>A p.Gly153Arg p.G153R ENST00000356731 153 Ggg/Agg 0 +HOXB2 UCSF GRCh37 17 46620758 46620758 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 34 16 30 0 ENST00000330070.4:c.743C>T p.Pro248Leu p.P248L ENST00000330070 NM_002145.3 248 cCg/cTg 0 +HP1BP3 UCSF GRCh37 1 21106840 21106840 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 59 9 55 0 ENST00000312239.5:c.94G>A p.Glu32Lys p.E32K ENST00000312239 NM_016287.3 32 Gag/Aag 0 +HRNR UCSF GRCh37 1 152193713 152193713 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 285 65 301 0 ENST00000368801.2:c.392G>A p.Ser131Asn p.S131N ENST00000368801 NM_001009931.2 131 aGt/aAt 0 +HSP90AB1 UCSF GRCh37 6 44216400 44216400 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 546 86 320 0 ENST00000353801.3:c.34G>A p.Val12Met p.V12M ENST00000353801 NM_001271969.1 12 Gtg/Atg 0 +HSPA4 UCSF GRCh37 5 132426984 132426984 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 191 47 246 1 ENST00000304858.2:c.1478C>A p.Ser493Tyr p.S493Y ENST00000304858 NM_002154.3 493 tCc/tAc 0 +HSPG2 UCSF GRCh37 1 22206919 22206919 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 55 13 103 0 ENST00000374695.3:c.2132C>T p.Ala711Val p.A711V ENST00000374695 NM_005529.5 711 gCc/gTc 0 +HTR7 UCSF GRCh37 10 92508880 92508880 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 36 200 1 ENST00000336152.3:c.1011C>T p.Thr337= p.T337= ENST00000336152 NM_019859.3 337 acC/acT 0 +HUWE1 UCSF GRCh37 X 53579645 53579645 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 57 28 91 0 ENST00000262854.6:c.8704G>A p.Gly2902Ser p.G2902S ENST00000262854 NM_031407.5 2902 Ggc/Agc 0 +IARS2 UCSF GRCh37 1 220273858 220273858 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 84 16 74 0 ENST00000366922.1:c.201C>T p.Phe67= p.F67= ENST00000366922 67 ttC/ttT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 30 74 126 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IDO1 UCSF GRCh37 8 39776390 39776390 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 381 65 450 0 ENST00000518237.1:c.360G>A p.Leu120= p.L120= ENST00000518237 NM_002164.5 120 ctG/ctA 0 +IFITM1 UCSF GRCh37 11 314927 314927 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 48 18 172 0 ENST00000328221.5:c.192G>A p.Arg64= p.R64= ENST00000328221 64 agG/agA 0 +IFT172 UCSF GRCh37 2 27668177 27668177 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 4 34 0 ENST00000260570.3:c.5054C>T p.Pro1685Leu p.P1685L ENST00000260570 NM_015662.1 1685 cCc/cTc 0 +IFT172 UCSF GRCh37 2 27704119 27704119 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 39 21 65 0 ENST00000260570.3:c.579G>A p.Leu193= p.L193= ENST00000260570 NM_015662.1 193 ttG/ttA 0 +IGSF10 UCSF GRCh37 3 151166450 151166450 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 189 50 258 0 ENST00000282466.3:c.1319G>A p.Arg440Lys p.R440K ENST00000282466 NM_178822.4 440 aGa/aAa 0 +IGSF22 UCSF GRCh37 11 18730979 18730979 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 49 230 0 ENST00000319338.6:c.2650G>A p.Glu884Lys p.E884K ENST00000319338 884 Gag/Aag 0 +IGSF9 UCSF GRCh37 1 159900927 159900927 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 70 23 95 1 ENST00000368094.1:c.1637+1G>A p.X546_splice ENST00000368094 NM_001135050.1 0 +IKBKAP UCSF GRCh37 9 111679912 111679912 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 207 41 185 0 ENST00000374647.5:c.779C>T p.Pro260Leu p.P260L ENST00000374647 NM_003640.3 260 cCc/cTc 0 +IKBKAP UCSF GRCh37 9 111692117 111692117 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 242 28 295 1 ENST00000374647.5:c.235G>A p.Asp79Asn p.D79N ENST00000374647 NM_003640.3 79 Gat/Aat 0 +IL10RB UCSF GRCh37 21 34648906 34648906 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 365 55 295 1 ENST00000290200.2:c.179G>A p.Arg60Lys p.R60K ENST00000290200 NM_000628.4 60 aGg/aAg 0 +INA UCSF GRCh37 10 105037185 105037185 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 16 73 0 ENST00000369849.4:c.217G>A p.Asp73Asn p.D73N ENST00000369849 NM_032727.3 73 Gac/Aac 0 +INA UCSF GRCh37 10 105037961 105037961 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 12 6 33 0 ENST00000369849.4:c.993G>A p.Gly331= p.G331= ENST00000369849 NM_032727.3 331 ggG/ggA 0 +INCENP UCSF GRCh37 11 61917663 61917663 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 32 184 0 ENST00000394818.3:c.2526C>T p.Ile842= p.I842= ENST00000394818 NM_001040694.1 842 atC/atT 0 +INF2 UCSF GRCh37 14 105169465 105169465 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 34 193 0 ENST00000392634.4:c.415G>A p.Val139Met p.V139M ENST00000392634 NM_022489.3 139 Gtg/Atg 0 +INO80 UCSF GRCh37 15 41289801 41289801 + splice_acceptor_variant Splice_Site SNP T T A NOVEL P21_Rec Untested WXS Illumina HiSeq 65 17 86 1 ENST00000361937.3:c.3498-2A>T p.X1166_splice ENST00000361937 0 +INO80 UCSF GRCh37 15 41313228 41313228 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 94 30 135 0 ENST00000361937.3:c.3144G>A p.Gln1048= p.Q1048= ENST00000361937 1048 caG/caA 0 +INPPL1 UCSF GRCh37 11 71948227 71948227 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 104 96 223 0 ENST00000298229.2:c.2939G>C p.Ser980Thr p.S980T ENST00000298229 NM_001567.3 980 aGc/aCc 0 +INSR UCSF GRCh37 19 7141710 7141710 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 110 22 148 0 ENST00000302850.5:c.2660G>A p.Ser887Asn p.S887N ENST00000302850 NM_000208.2 887 aGt/aAt 0 +INSRR UCSF GRCh37 1 156828357 156828357 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 109 23 137 0 ENST00000368195.3:c.57C>T p.Ser19= p.S19= ENST00000368195 NM_014215.2 19 tcC/tcT 0 +INTS10 UCSF GRCh37 8 19703277 19703277 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 21 80 0 ENST00000397977.3:c.1945G>A p.Glu649Lys p.E649K ENST00000397977 NM_018142.2 649 Gaa/Aaa 0 +INVS UCSF GRCh37 9 103054908 103054908 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 95 31 125 0 ENST00000262457.2:c.2369C>T p.Pro790Leu p.P790L ENST00000262457 NM_014425.3 790 cCc/cTc 0 +IQGAP3 UCSF GRCh37 1 156504354 156504354 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 58 10 72 0 ENST00000361170.2:c.3679G>A p.Gly1227Arg p.G1227R ENST00000361170 NM_178229.4 1227 Ggg/Agg 0 +IRAK4 UCSF GRCh37 12 44165049 44165049 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 65 27 86 0 ENST00000551736.1:c.188G>A p.Gly63Glu p.G63E ENST00000551736 NM_001114182.2 63 gGa/gAa 0 +IRF2BP2 UCSF GRCh37 1 234743379 234743379 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 147 38 212 0 ENST00000366609.3:c.1268C>T p.Ser423Phe p.S423F ENST00000366609 NM_182972.2 423 tCc/tTc 0 +IRF2BPL UCSF GRCh37 14 77491854 77491854 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 96 45 169 0 ENST00000238647.3:c.2282G>A p.Gly761Glu p.G761E ENST00000238647 NM_024496.3 761 gGa/gAa 0 +IRF2BPL UCSF GRCh37 14 77492290 77492290 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 17 5 21 0 ENST00000238647.3:c.1846G>A p.Ala616Thr p.A616T ENST00000238647 NM_024496.3 616 Gcc/Acc 0 +ITGB1 UCSF GRCh37 10 33211251 33211251 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 195 58 176 0 ENST00000302278.3:c.1062G>A p.Lys354= p.K354= ENST00000302278 NM_002211.3 354 aaG/aaA 0 +ITGB2 UCSF GRCh37 21 46306818 46306818 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 14 112 0 ENST00000302347.5:c.2081-1G>A p.X694_splice ENST00000302347 NM_000211.3 0 +ITIH4 UCSF GRCh37 3 52848224 52848224 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 16 77 0 ENST00000266041.4:c.2626+1G>A p.X876_splice ENST00000266041 NM_002218.4 0 +ITIH5 UCSF GRCh37 10 7618900 7618900 + synonymous_variant Silent SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 111 58 137 0 ENST00000256861.6:c.1494C>A p.Ala498= p.A498= ENST00000256861 NM_030569.6 498 gcC/gcA 0 +JAKMIP2 UCSF GRCh37 5 147020296 147020296 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 93 49 233 0 ENST00000265272.5:c.1372C>T p.Pro458Ser p.P458S ENST00000265272 NM_014790.4 458 Cca/Tca 0 +JAM2 UCSF GRCh37 21 27071072 27071072 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 145 24 130 0 ENST00000480456.1:c.478G>A p.Gly160Arg p.G160R ENST00000480456 NM_001270407.1 160 Ggg/Agg 0 +JARID2 UCSF GRCh37 6 15496685 15496685 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 156 22 147 0 ENST00000341776.2:c.1229G>A p.Ser410Asn p.S410N ENST00000341776 NM_004973.3 410 aGt/aAt 0 +KAT6B UCSF GRCh37 10 76737107 76737107 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 22 140 0 ENST00000287239.4:c.2027G>A p.Ser676Asn p.S676N ENST00000287239 NM_001256468.1 676 aGt/aAt 0 +KCNH7 UCSF GRCh37 2 163302755 163302755 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 93 25 200 0 ENST00000332142.5:c.1327G>A p.Glu443Lys p.E443K ENST00000332142 NM_033272.3 443 Gaa/Aaa 0 +KCNJ14 UCSF GRCh37 19 48967778 48967778 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 30 147 0 ENST00000342291.2:c.1055C>T p.Thr352Ile p.T352I ENST00000342291 NM_013348.3 352 aCt/aTt 0 +KCNJ3 UCSF GRCh37 2 155711377 155711377 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 128 31 197 0 ENST00000295101.2:c.1058C>T p.Thr353Ile p.T353I ENST00000295101 NM_002239.3 353 aCc/aTc 0 +KCNMA1 UCSF GRCh37 10 78870030 78870030 + synonymous_variant Silent SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 194 82 334 0 ENST00000286628.8:c.1032T>C p.Tyr344= p.Y344= ENST00000286628 NM_001161352.1 344 taT/taC 0 +KCNQ5 UCSF GRCh37 6 73332281 73332281 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 16 7 44 0 ENST00000370398.1:c.364C>T p.Pro122Ser p.P122S ENST00000370398 NM_019842.3 122 Ccc/Tcc 0 +KCTD15 UCSF GRCh37 19 34302256 34302256 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 14 60 0 ENST00000430256.3:c.492G>A p.Arg164= p.R164= ENST00000430256 164 cgG/cgA 0 +KDM4D UCSF GRCh37 11 94731128 94731128 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 115 59 318 0 ENST00000335080.5:c.592C>T p.Leu198Phe p.L198F ENST00000335080 NM_018039.2 198 Ctt/Ttt 0 +KDM5C UCSF GRCh37 X 53225875 53225875 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 36 27 78 0 ENST00000375401.3:c.2974G>A p.Glu992Lys p.E992K ENST00000375401 NM_004187.3 992 Gag/Aag 0 +KDM5D UCSF GRCh37 Y 21877842 21877842 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 46 106 0 ENST00000317961.4:c.2080G>A p.Glu694Lys p.E694K ENST00000317961 NM_004653.4 694 Gaa/Aaa 0 +KDM5D UCSF GRCh37 Y 21868399 21868399 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 13 11 45 0 ENST00000317961.4:c.4197G>A p.Glu1399= p.E1399= ENST00000317961 NM_004653.4 1399 gaG/gaA 0 +KIAA0020 UCSF GRCh37 9 2837245 2837245 + missense_variant Missense_Mutation SNP T T A NOVEL P21_Rec Untested WXS Illumina HiSeq 71 245 542 0 ENST00000397885.2:c.239A>T p.Asn80Ile p.N80I ENST00000397885 NM_014878.4 80 aAc/aTc 0 +KIAA0319L UCSF GRCh37 1 35944779 35944779 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 26 125 0 ENST00000325722.3:c.701C>T p.Thr234Ile p.T234I ENST00000325722 NM_024874.4 234 aCc/aTc 0 +KIAA0753 UCSF GRCh37 17 6531854 6531854 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 53 210 0 ENST00000361413.3:c.301G>A p.Val101Ile p.V101I ENST00000361413 NM_014804.2 101 Gtc/Atc 0 +KIAA0825 UCSF GRCh37 5 93775796 93775796 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 182 29 233 0 ENST00000513200.3:c.2388G>A p.Glu796= p.E796= ENST00000513200 NM_001145678.1 796 gaG/gaA 0 +KIAA0889 UCSF GRCh37 20 35421664 35421664 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 15 82 0 ENST00000237536.4:c.4821C>T p.Val1607= p.V1607= ENST00000237536 NM_080627.2 1607 gtC/gtT 0 +KIAA1191 UCSF GRCh37 5 175774703 175774703 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 102 14 215 0 ENST00000298569.4:c.818C>T p.Pro273Leu p.P273L ENST00000298569 NM_020444.3 273 cCc/cTc 0 +KIAA1199 UCSF GRCh37 15 81201554 81201554 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 93 18 139 0 ENST00000220244.3:c.1704G>A p.Arg568= p.R568= ENST00000220244 NM_018689.1 568 agG/agA 0 +KIAA1211 UCSF GRCh37 4 57181573 57181573 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 70 8 64 0 ENST00000264229.6:c.1905G>A p.Gly635= p.G635= ENST00000264229 NM_020722.1 635 ggG/ggA 0 +KIAA1486 UCSF GRCh37 2 226378195 226378195 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 197 82 368 0 ENST00000272907.6:c.330C>T p.Cys110= p.C110= ENST00000272907 NM_020864.1 110 tgC/tgT 0 +KIAA1704 UCSF GRCh37 13 45589195 45589195 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 26 8 90 0 ENST00000379151.4:c.517G>A p.Glu173Lys p.E173K ENST00000379151 NM_018559.2 173 Gaa/Aaa 0 +KIAA2018 UCSF GRCh37 3 113376584 113376584 + synonymous_variant Silent SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 234 77 296 0 ENST00000316407.4:c.3945A>G p.Pro1315= p.P1315= ENST00000316407 NM_001009899.2 1315 ccA/ccG 0 +KIF13A UCSF GRCh37 6 17817420 17817422 + frameshift_variant Frame_Shift_Del DEL CTA CTA TT NOVEL P21_Rec Untested WXS Illumina HiSeq 30 0 ENST00000259711.6:c.1829_1831delinsAA p.Leu610GlnfsTer8 p.L610Qfs*8 ENST00000259711 NM_022113.5 610 cTAGaa/cAAaa 0 +KIF17 UCSF GRCh37 1 20991147 20991147 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 71 9 98 0 ENST00000247986.2:c.3020C>T p.Ser1007Phe p.S1007F ENST00000247986 1007 tCc/tTc 0 +KIF1B UCSF GRCh37 1 10363361 10363361 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 120 21 132 0 ENST00000377086.1:c.2115+6057G>A *705* ENST00000377086 0 +KIF20B UCSF GRCh37 10 91483742 91483742 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 56 11 112 0 ENST00000371728.3:c.1744G>A p.Asp582Asn p.D582N ENST00000371728 NM_001284259.1 582 Gac/Aac 0 +KIF23 UCSF GRCh37 15 69737233 69737233 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 43 210 0 ENST00000260363.4:c.2484G>A p.Met828Ile p.M828I ENST00000260363 NM_138555.3 828 atG/atA 0 +KIF23 UCSF GRCh37 15 69738636 69738636 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 100 21 96 0 ENST00000260363.4:c.2729G>A p.Arg910Lys p.R910K ENST00000260363 NM_138555.3 910 aGa/aAa 0 +KIF6 UCSF GRCh37 6 39563952 39563952 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 89 98 0 ENST00000287152.7:c.724C>T p.Arg242Ter p.R242* ENST00000287152 NM_145027.4 242 Cga/Tga 0 +KIFC1 UCSF GRCh37 6 33372666 33372666 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 153 20 120 0 ENST00000428849.2:c.794G>A p.Ser265Asn p.S265N ENST00000428849 NM_002263.3 265 aGc/aAc 0 +KL UCSF GRCh37 13 33591228 33591228 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 27 3 46 0 ENST00000380099.3:c.650G>A p.Arg217Lys p.R217K ENST00000380099 NM_004795.3 217 aGg/aAg 0 +KLHDC7B UCSF GRCh37 22 50988351 50988351 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 24 4 39 0 ENST00000395676.2:c.1756C>T p.Pro586Ser p.P586S ENST00000395676 NM_138433.3 586 Cct/Tct 0 +KLHL20 UCSF GRCh37 1 173702880 173702880 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 146 29 190 0 ENST00000209884.4:c.52G>A p.Gly18Arg p.G18R ENST00000209884 NM_014458.3 18 Gga/Aga 0 +KLK3 UCSF GRCh37 19 51362853 51362853 + intron_variant Intron SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 104 25 159 0 ENST00000326003.2:c.631-375C>T *211* ENST00000326003 NM_001030047.1 0 +KLRC2 UCSF GRCh37 12 10586474 10586474 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 185 68 163 1 ENST00000381902.2:c.399G>A p.Lys133= p.K133= ENST00000381902 NM_002260.3 133 aaG/aaA 0 +KMO UCSF GRCh37 1 241755331 241755331 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 183 37 233 0 ENST00000366559.4:c.1337C>T p.Ser446Leu p.S446L ENST00000366559 NM_003679.4 446 tCa/tTa 0 +KPNA2 UCSF GRCh37 17 66040553 66040553 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 398 115 528 0 ENST00000330459.3:c.1281C>T p.Asn427= p.N427= ENST00000330459 NM_002266.2 427 aaC/aaT 0 +KPNB1 UCSF GRCh37 17 45755738 45755738 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 122 17 140 0 ENST00000290158.4:c.2312G>A p.Gly771Glu p.G771E ENST00000290158 NM_002265.5 771 gGa/gAa 0 +KRT9 UCSF GRCh37 17 39728026 39728026 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 19 12 38 0 ENST00000246662.4:c.219C>T p.Tyr73= p.Y73= ENST00000246662 NM_000226.3 73 taC/taT 0 +KRTAP4-1 UCSF GRCh37 17 39341039 39341039 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 93 37 160 0 ENST00000398472.1:c.68C>A p.Thr23Asn p.T23N ENST00000398472 23 aCc/aAc 0 +KSR1 UCSF GRCh37 17 25909824 25909824 + missense_variant Missense_Mutation SNP C C T snp132_rs34914492 P21_Rec Untested WXS Illumina HiSeq 44 14 77 0 ENST00000398988.3:c.262C>T p.Pro88Ser p.P88S ENST00000398988 NM_014238.1 88 Cca/Tca 0 +LAMA1 UCSF GRCh37 18 7023359 7023359 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 70 19 110 0 ENST00000389658.3:c.2505C>T p.Tyr835= p.Y835= ENST00000389658 NM_005559.3 835 taC/taT 0 +LAMA3 UCSF GRCh37 18 21494764 21494764 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 8 51 0 ENST00000313654.9:c.7584C>T p.Leu2528= p.L2528= ENST00000313654 NM_198129.1 2528 ctC/ctT 0 +LAMB4 UCSF GRCh37 7 107671346 107671346 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 163 32 228 0 ENST00000205386.4:c.4897C>T p.Leu1633= p.L1633= ENST00000205386 1633 Ctg/Ttg 0 +LETM1 UCSF GRCh37 4 1823925 1823925 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 99 11 119 0 ENST00000302787.2:c.1591G>A p.Val531Met p.V531M ENST00000302787 NM_012318.2 531 Gtg/Atg 0 +LETM1 UCSF GRCh37 4 1827392 1827392 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 61 20 74 0 ENST00000302787.2:c.1099G>A p.Val367Met p.V367M ENST00000302787 NM_012318.2 367 Gtg/Atg 0 +LGALS14 UCSF GRCh37 19 40197953 40197953 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 366 97 482 1 ENST00000392052.3:c.228G>A p.Glu76= p.E76= ENST00000392052 NM_020129.2 76 gaG/gaA 0 +LIX1L UCSF GRCh37 1 145487444 145487444 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 118 25 131 0 ENST00000369308.3:c.433G>A p.Gly145Arg p.G145R ENST00000369308 NM_153713.2 145 Gga/Aga 0 +LMOD2 UCSF GRCh37 7 123303046 123303046 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 36 16 65 0 ENST00000458573.2:c.1406C>T p.Ala469Val p.A469V ENST00000458573 NM_207163.1 469 gCc/gTc 0 +LOXL3 UCSF GRCh37 2 74779470 74779470 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 34 9 82 0 ENST00000264094.3:c.292G>A p.Ala98Thr p.A98T ENST00000264094 NM_032603.2 98 Gcc/Acc 0 +LPA UCSF GRCh37 6 160952788 160952788 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 65 40 221 0 ENST00000316300.5:c.6096G>A p.Trp2032Ter p.W2032* ENST00000316300 2032 tgG/tgA 0 +LPA UCSF GRCh37 6 161056204 161056204 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 487 62 972 0 ENST00000316300.5:c.1026G>A p.Ala342= p.A342= ENST00000316300 342 gcG/gcA 0 +LPAR3 UCSF GRCh37 1 85331417 85331417 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 456 91 694 0 ENST00000370611.3:c.387G>A p.Met129Ile p.M129I ENST00000370611 NM_012152.2 129 atG/atA 0 +LPHN3 UCSF GRCh37 4 62453029 62453029 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 59 235 0 ENST00000514591.1:c.140G>A p.Gly47Glu p.G47E ENST00000514591 47 gGa/gAa 0 +LRMP UCSF GRCh37 12 25232607 25232607 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 152 35 119 0 ENST00000354454.3:c.154C>T p.Leu52= p.L52= ENST00000354454 NM_006152.3 52 Ctg/Ttg 0 +LRRC19 UCSF GRCh37 9 26995558 26995558 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 39 8 46 0 ENST00000380055.5:c.1074C>T p.Asp358= p.D358= ENST00000380055 NM_022901.2 358 gaC/gaT 0 +LRRC8C UCSF GRCh37 1 90179564 90179564 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 139 41 212 0 ENST00000370454.4:c.1435G>A p.Val479Ile p.V479I ENST00000370454 NM_032270.4 479 Gtc/Atc 0 +LRRC8C UCSF GRCh37 1 90180190 90180190 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 118 34 121 0 ENST00000370454.4:c.2061C>T p.Tyr687= p.Y687= ENST00000370454 NM_032270.4 687 taC/taT 0 +LRRIQ1 UCSF GRCh37 12 85432020 85432020 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 76 21 126 0 ENST00000393217.2:c.66C>T p.Ser22= p.S22= ENST00000393217 NM_001079910.1 22 tcC/tcT 0 +LRRK2 UCSF GRCh37 12 40758823 40758823 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 143 27 136 0 ENST00000298910.7:c.7361C>T p.Ser2454Leu p.S2454L ENST00000298910 NM_198578.3 2454 tCg/tTg 0 +LRRTM2 UCSF GRCh37 5 138209046 138209046 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 163 93 440 0 ENST00000274711.6:c.1204G>A p.Gly402Ser p.G402S ENST00000274711 NM_015564.2 402 Ggc/Agc 0 +LTBP2 UCSF GRCh37 14 75078270 75078270 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.006,1000g2011may_all_0.0052 P21_Rec Untested WXS Illumina HiSeq 32 6 40 0 ENST00000261978.4:c.378C>T p.Pro126= p.P126= ENST00000261978 NM_000428.2 126 ccC/ccT 0 +LTN1 UCSF GRCh37 21 30329684 30329684 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 150 28 114 0 ENST00000361371.5:c.2862G>T p.Trp954Cys p.W954C ENST00000361371 954 tgG/tgT 0 +M6PR UCSF GRCh37 12 9098119 9098119 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 169 36 199 0 ENST00000000412.3:c.238G>A p.Glu80Lys p.E80K ENST00000000412 NM_002355.3 80 Gaa/Aaa 0 +MACF1 UCSF GRCh37 1 39753082 39753082 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 334 60 462 0 ENST00000372915.3:c.1648G>A p.Ala550Thr p.A550T ENST00000372915 550 Gca/Aca 0 +MAGI2 UCSF GRCh37 7 78636498 78636498 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 20 132 0 ENST00000354212.4:c.326G>A p.Arg109His p.R109H ENST00000354212 NM_012301.3 109 cGt/cAt 0 +MAN2A1 UCSF GRCh37 5 109200736 109200736 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 25 110 0 ENST00000261483.4:c.3172-1G>A p.X1058_splice ENST00000261483 NM_002372.2 0 +MAP2 UCSF GRCh37 2 210560059 210560059 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 352 66 306 0 ENST00000360351.4:c.3165G>A p.Gln1055= p.Q1055= ENST00000360351 NM_002374.3 1055 caG/caA 0 +MAP3K1 UCSF GRCh37 5 56177036 56177036 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 87 17 85 0 ENST00000399503.3:c.2306C>T p.Pro769Leu p.P769L ENST00000399503 NM_005921.1 769 cCt/cTt 0 +MAP3K14 UCSF GRCh37 17 43344879 43344879 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 58 15 69 0 ENST00000344686.2:n.2326G>A *776* ENST00000344686 0 +MAP3K6 UCSF GRCh37 1 27683593 27683593 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 35 8 55 0 ENST00000357582.2:c.3271C>T p.Leu1091Phe p.L1091F ENST00000357582 1091 Ctc/Ttc 0 +MAP4K2 UCSF GRCh37 11 64557083 64557083 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 25 8 47 0 ENST00000294066.2:c.2389G>A p.Glu797Lys p.E797K ENST00000294066 NM_004579.3 797 Gag/Aag 0 +MAP4K4 UCSF GRCh37 2 102488148 102488148 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 90 30 173 0 ENST00000347699.4:c.2517+1271G>A *839* ENST00000347699 NM_145687.3 0 +MAP6 UCSF GRCh37 11 75299168 75299168 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 173 46 231 0 ENST00000304771.3:c.1378G>A p.Asp460Asn p.D460N ENST00000304771 NM_033063.1 460 Gac/Aac 0 +MAP7D1 UCSF GRCh37 1 36644187 36644187 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 13 4 19 0 ENST00000373151.2:c.1876G>A p.Glu626Lys p.E626K ENST00000373151 NM_018067.3 626 Gaa/Aaa 0 +MAP7D1 UCSF GRCh37 1 36638150 36638150 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 8 45 0 ENST00000373151.2:c.546G>A p.Leu182= p.L182= ENST00000373151 NM_018067.3 182 ctG/ctA 0 +MAPK13 UCSF GRCh37 6 36106555 36106555 + missense_variant,splice_region_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 91 14 73 0 ENST00000211287.4:c.839A>T p.Gln280Leu p.Q280L ENST00000211287 NM_002754.4 280 cAg/cTg 0 +MAPKAPK5 UCSF GRCh37 12 112321443 112321443 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 210 73 407 0 ENST00000551404.2:c.719C>T p.Pro240Leu p.P240L ENST00000551404 240 cCt/cTt 0 +MBTPS1 UCSF GRCh37 16 84089694 84089694 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 30 175 0 ENST00000343411.3:c.2878G>A p.Val960Met p.V960M ENST00000343411 NM_003791.2 960 Gtg/Atg 0 +MCC UCSF GRCh37 5 112478934 112478934 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 75 17 80 0 ENST00000302475.4:c.295C>T p.Leu99= p.L99= ENST00000302475 NM_002387.2 99 Ctg/Ttg 0 +MCM3AP UCSF GRCh37 21 47695166 47695166 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 45 14 55 0 ENST00000291688.1:c.1932G>A p.Lys644= p.K644= ENST00000291688 NM_003906.3 644 aaG/aaA 0 +MCM4 UCSF GRCh37 8 48885522 48885522 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 12 81 0 ENST00000262105.2:c.2034G>A p.Glu678= p.E678= ENST00000262105 NM_005914.3 678 gaG/gaA 0 +MCM6 UCSF GRCh37 2 136610432 136610432 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 24 112 0 ENST00000264156.2:c.1680G>A p.Glu560= p.E560= ENST00000264156 NM_005915.5 560 gaG/gaA 0 +MECOM UCSF GRCh37 3 169099279 169099279 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 112 91 176 1 ENST00000486748.1:c.143T>C p.Ile48Thr p.I48T ENST00000486748 48 aTa/aCa 0 +MED12 UCSF GRCh37 X 70341647 70341647 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 53 28 73 0 ENST00000374080.3:c.1082G>A p.Gly361Asp p.G361D ENST00000374080 361 gGc/gAc 0 +MED12 UCSF GRCh37 X 70347192 70347192 + synonymous_variant Silent SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 37 24 48 0 ENST00000374080.3:c.2856T>C p.Cys952= p.C952= ENST00000374080 952 tgT/tgC 0 +MFAP1 UCSF GRCh37 15 44109561 44109561 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 190 47 212 0 ENST00000267812.3:c.165G>A p.Glu55= p.E55= ENST00000267812 NM_005926.2 55 gaG/gaA 0 +MFHAS1 UCSF GRCh37 8 8748927 8748927 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 102 47 150 0 ENST00000276282.6:c.1642G>A p.Glu548Lys p.E548K ENST00000276282 NM_004225.2 548 Gag/Aag 0 +MFHAS1 UCSF GRCh37 8 8749257 8749257 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 86 27 151 0 ENST00000276282.6:c.1312C>T p.Pro438Ser p.P438S ENST00000276282 NM_004225.2 438 Cca/Tca 0 +MFSD8 UCSF GRCh37 4 128861044 128861044 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 34 39 127 0 ENST00000296468.3:c.662G>A p.Gly221Glu p.G221E ENST00000296468 NM_152778.2 221 gGa/gAa 0 +MICAL3 UCSF GRCh37 22 18347444 18347444 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 3 36 0 ENST00000441493.2:c.2605+221C>T *869* ENST00000441493 NM_015241.2 0 +MIER1 UCSF GRCh37 1 67411859 67411859 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 153 37 162 0 ENST00000355356.3:c.61G>A p.Glu21Lys p.E21K ENST00000355356 NM_001077701.2 21 Gaa/Aaa 0 +MIOS UCSF GRCh37 7 7646697 7646697 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 58 9 122 1 ENST00000340080.4:c.2602G>A p.Val868Ile p.V868I ENST00000340080 NM_019005.3 868 Gta/Ata 0 +MKI67 UCSF GRCh37 10 129902612 129902612 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 72 386 0 ENST00000368654.3:c.7492G>A p.Val2498Ile p.V2498I ENST00000368654 NM_002417.4 2498 Gtc/Atc 0 +MKRN2 UCSF GRCh37 3 12623345 12623345 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 284 76 310 0 ENST00000170447.7:c.1007C>T p.Thr336Ile p.T336I ENST00000170447 NM_014160.4 336 aCc/aTc 0 +MLF2 UCSF GRCh37 12 6861100 6861100 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 157 26 183 0 ENST00000203630.5:c.171G>A p.Arg57= p.R57= ENST00000203630 57 cgG/cgA 0 +MLL UCSF GRCh37 11 118373420 118373420 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 101 23 259 1 ENST00000389506.5:c.6804G>A p.Arg2268= p.R2268= ENST00000389506 2268 agG/agA 0 +MLL2 UCSF GRCh37 12 49443842 49443842 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 85 32 128 0 ENST00000301067.7:c.3529G>A p.Gly1177Arg p.G1177R ENST00000301067 NM_003482.3 1177 Ggg/Agg 0 +MLL3 UCSF GRCh37 7 152027799 152027799 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 37 178 0 ENST00000262189.6:c.276G>A p.Glu92= p.E92= ENST00000262189 NM_170606.2 92 gaG/gaA 0 +MMS19 UCSF GRCh37 10 99236698 99236698 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 150 61 336 0 ENST00000370782.2:c.516C>T p.Asp172= p.D172= ENST00000370782 172 gaC/gaT 0 +MOV10L1 UCSF GRCh37 22 50572463 50572463 + synonymous_variant Silent SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 42 8 42 0 ENST00000262794.5:c.1938A>G p.Ala646= p.A646= ENST00000262794 NM_018995.2 646 gcA/gcG 0 +MRPL39 UCSF GRCh37 21 26973701 26973701 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 89 15 84 0 ENST00000352957.4:c.499G>A p.Val167Ile p.V167I ENST00000352957 NM_017446.3 167 Gtc/Atc 0 +MRPL48 UCSF GRCh37 11 73556001 73556001 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 183 56 210 0 ENST00000310614.7:c.351C>T p.Leu117= p.L117= ENST00000310614 NM_016055.5 117 ctC/ctT 0 +MRPS18B UCSF GRCh37 6 30593516 30593516 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 234 44 198 0 ENST00000259873.4:c.719C>T p.Pro240Leu p.P240L ENST00000259873 NM_014046.3 240 cCt/cTt 0 +MRPS7 UCSF GRCh37 17 73257992 73257992 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 20 3 22 0 ENST00000245539.6:c.11C>T p.Pro4Leu p.P4L ENST00000245539 NM_015971.3 4 cCc/cTc 0 +MTERFD1 UCSF GRCh37 8 97256170 97256170 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 173 32 133 0 ENST00000287025.3:c.1036C>T p.His346Tyr p.H346Y ENST00000287025 NM_015942.3 346 Cac/Tac 0 +MTHFR UCSF GRCh37 1 11862938 11862938 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 71 20 160 0 ENST00000376590.3:c.236G>A p.Arg79Lys p.R79K ENST00000376590 NM_005957.4 79 aGg/aAg 0 +MTMR10 UCSF GRCh37 15 31253149 31253149 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 235 48 264 0 ENST00000435680.1:c.693C>T p.Ile231= p.I231= ENST00000435680 NM_017762.2 231 atC/atT 0 +MUC16 UCSF GRCh37 19 9071859 9071859 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 445 115 601 1 ENST00000397910.4:c.15587G>A p.Ser5196Asn p.S5196N ENST00000397910 NM_024690.2 5196 aGt/aAt 0 +MUC5B UCSF GRCh37 11 1264731 1264731 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 86 38 219 0 ENST00000529681.1:c.6621C>T p.Pro2207= p.P2207= ENST00000529681 NM_002458.2 2207 ccC/ccT 0 +MX1 UCSF GRCh37 21 42817417 42817417 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 215 46 199 0 ENST00000398598.3:c.1051C>G p.Gln351Glu p.Q351E ENST00000398598 NM_002462.3 351 Cag/Gag 0 +MYCBP2 UCSF GRCh37 13 77844511 77844511 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 38 28 109 0 ENST00000357337.6:c.994C>T p.Gln332Ter p.Q332* ENST00000357337 332 Cag/Tag 0 +MYCBP2 UCSF GRCh37 13 77635322 77635322 + stop_gained Nonsense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 39 19 99 0 ENST00000357337.6:c.12904G>T p.Glu4302Ter p.E4302* ENST00000357337 4302 Gaa/Taa 0 +MYH1 UCSF GRCh37 17 10402076 10402076 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 153 55 255 0 ENST00000226207.5:c.4048C>T p.Gln1350Ter p.Q1350* ENST00000226207 NM_005963.3 1350 Cag/Tag 0 +MYH6 UCSF GRCh37 14 23873582 23873582 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 142 63 267 0 ENST00000356287.3:c.658C>T p.Gln220Ter p.Q220* ENST00000356287 220 Cag/Tag 0 +MYH9 UCSF GRCh37 22 36681211 36681211 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 120 30 201 0 ENST00000216181.5:c.5439G>A p.Glu1813= p.E1813= ENST00000216181 NM_002473.4 1813 gaG/gaA 0 +MYLK UCSF GRCh37 3 123333125 123333125 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 191 71 283 0 ENST00000360304.3:c.5572G>C p.Asp1858His p.D1858H ENST00000360304 NM_053025.3 1858 Gac/Cac 0 +MYO1C UCSF GRCh37 17 1384175 1384175 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 61 22 107 0 ENST00000359786.5:c.632C>T p.Ala211Val p.A211V ENST00000359786 NM_001080779.1 211 gCc/gTc 0 +MYO1G UCSF GRCh37 7 45005692 45005692 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 41 9 78 0 ENST00000258787.7:c.2137A>G p.Ile713Val p.I713V ENST00000258787 NM_033054.2 713 Att/Gtt 0 +MYO7B UCSF GRCh37 2 128378042 128378042 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 26 15 63 0 ENST00000409816.2:c.3447+1G>A p.X1149_splice ENST00000409816 0 +MZT2A UCSF GRCh37 2 132241665 132241665 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 101 36 196 0 ENST00000309451.6:c.446C>T p.Pro149Leu p.P149L ENST00000309451 NM_001085365.1 149 cCt/cTt 0 +N4BP2 UCSF GRCh37 4 40144355 40144355 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 78 23 144 0 ENST00000261435.6:c.4848C>T p.Tyr1616= p.Y1616= ENST00000261435 NM_018177.4 1616 taC/taT 0 +NALCN UCSF GRCh37 13 101725987 101725987 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 42 15 111 0 ENST00000251127.6:c.4146G>A p.Leu1382= p.L1382= ENST00000251127 NM_052867.2 1382 ctG/ctA 0 +NAT8L UCSF GRCh37 4 2062856 2062856 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 29 9 38 0 ENST00000423729.2:c.508G>A p.Ala170Thr p.A170T ENST00000423729 NM_178557.3 170 Gcg/Acg 0 +NBPF10 UCSF GRCh37 1 145327548 145327548 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 23 7 17 0 ENST00000342960.5:c.4105A>G p.Asn1369Asp p.N1369D ENST00000342960 NM_001039703.5 1369 Aat/Gat 0 +NCBP1 UCSF GRCh37 9 100410414 100410414 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 89 15 123 1 ENST00000375147.3:c.806C>T p.Pro269Leu p.P269L ENST00000375147 NM_002486.4 269 cCt/cTt 0 +NCOA4 UCSF GRCh37 10 51585212 51585212 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 180 70 372 0 ENST00000452682.1:c.1359G>A p.Lys453= p.K453= ENST00000452682 NM_001145260.1 453 aaG/aaA 0 +NCOR2 UCSF GRCh37 12 124885083 124885083 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 101 47 212 0 ENST00000405201.1:c.1777G>A p.Glu593Lys p.E593K ENST00000405201 593 Gag/Aag 0 +NES UCSF GRCh37 1 156641450 156641450 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 138 40 138 0 ENST00000368223.3:c.2530G>A p.Glu844Lys p.E844K ENST00000368223 NM_006617.1 844 Gaa/Aaa 0 +NET1 UCSF GRCh37 10 5494478 5494478 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 17 88 0 ENST00000355029.4:c.521G>A p.Arg174Lys p.R174K ENST00000355029 NM_001047160.2 174 aGa/aAa 0 +NFASC UCSF GRCh37 1 204948528 204948528 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 244 60 345 0 ENST00000339876.6:c.2017G>A p.Gly673Arg p.G673R ENST00000339876 NM_001005388.2 673 Ggg/Agg 0 +NFATC3 UCSF GRCh37 16 68160380 68160380 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 128 43 182 0 ENST00000346183.3:c.1268C>T p.Pro423Leu p.P423L ENST00000346183 NM_173165.2 423 cCt/cTt 0 +NFIX UCSF GRCh37 19 13184830 13184830 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 158 38 220 0 ENST00000592199.1:c.808C>T p.Pro270Ser p.P270S ENST00000592199 270 Cct/Tct 0 +NHSL1 UCSF GRCh37 6 138745224 138745224 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 20 8 54 0 ENST00000427025.2:c.4827G>A p.Glu1609= p.E1609= ENST00000427025 NM_020464.1 1609 gaG/gaA 0 +NIN UCSF GRCh37 14 51211012 51211012 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 130 48 223 0 ENST00000382041.3:c.5136G>A p.Leu1712= p.L1712= ENST00000382041 NM_016350.4 1712 ctG/ctA 0 +NKTR UCSF GRCh37 3 42679042 42679042 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 69 316 1 ENST00000232978.8:c.1846C>T p.Pro616Ser p.P616S ENST00000232978 NM_005385.3 616 Cct/Tct 0 +NLGN4X UCSF GRCh37 X 6069303 6069303 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 55 155 0 ENST00000275857.6:c.205C>T p.Pro69Ser p.P69S ENST00000275857 NM_020742.2 69 Cca/Tca 0 +NLRC3 UCSF GRCh37 16 3614574 3614574 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 59 20 109 0 ENST00000359128.5:c.364G>A p.Val122Ile p.V122I ENST00000359128 122 Gtc/Atc 0 +NLRC3 UCSF GRCh37 16 3594294 3594294 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 120 42 206 0 ENST00000359128.5:c.2720G>A p.Cys907Tyr p.C907Y ENST00000359128 907 tGt/tAt 0 +NLRP8 UCSF GRCh37 19 56467155 56467155 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 130 38 144 0 ENST00000291971.3:c.1731C>T p.Cys577= p.C577= ENST00000291971 NM_176811.2 577 tgC/tgT 0 +NOS2 UCSF GRCh37 17 26091083 26091083 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 21 8 34 0 ENST00000313735.6:c.2516C>T p.Thr839Ile p.T839I ENST00000313735 NM_000625.4 839 aCc/aTc 0 +NOTCH2 UCSF GRCh37 1 120460309 120460309 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 28 164 0 ENST00000256646.2:c.6006C>T p.Asn2002= p.N2002= ENST00000256646 NM_024408.3 2002 aaC/aaT 0 +NOTCH3 UCSF GRCh37 19 15289943 15289943 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 37 27 61 0 ENST00000263388.2:c.3611C>T p.Ala1204Val p.A1204V ENST00000263388 NM_000435.2 1204 gCa/gTa 0 +NOTCH4 UCSF GRCh37 6 32165142 32165142 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 115 13 109 0 ENST00000375023.3:c.4986G>A p.Gln1662= p.Q1662= ENST00000375023 NM_004557.3 1662 caG/caA 0 +NPL UCSF GRCh37 1 182797922 182797922 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 38 125 0 ENST00000258317.2:c.842C>T p.Pro281Leu p.P281L ENST00000258317 281 cCc/cTc 0 +NPTN UCSF GRCh37 15 73862565 73862565 + missense_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 129 50 164 0 ENST00000345330.4:c.1040T>A p.Leu347Gln p.L347Q ENST00000345330 NM_012428.3 347 cTg/cAg 0 +NPY2R UCSF GRCh37 4 156135396 156135397 + frameshift_variant Frame_Shift_Del DEL TG TG - NOVEL P21_Rec Untested WXS Illumina HiSeq 26 0 ENST00000329476.3:c.308_309del p.Cys103SerfsTer90 p.C103Sfs*90 ENST00000329476 NM_000910.2 102 cTG/c 0 +NR0B1 UCSF GRCh37 X 30327138 30327138 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 26 3 39 0 ENST00000378970.4:c.343G>A p.Val115Met p.V115M ENST00000378970 NM_000475.4 115 Gtg/Atg 0 +NRBF2 UCSF GRCh37 10 64913831 64913831 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0014 P21_Rec Untested WXS Illumina HiSeq 61 16 110 0 ENST00000277746.6:c.717C>T p.Ala239= p.A239= ENST00000277746 NM_030759.3 239 gcC/gcT 0 +NSL1 UCSF GRCh37 1 212911796 212911796 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 174 30 161 0 ENST00000366977.3:c.800G>A p.Arg267Lys p.R267K ENST00000366977 NM_015471.3 267 aGa/aAa 0 +NT5C1B-RDH14 UCSF GRCh37 2 18736478 18736478 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 137 36 217 0 ENST00000381249.3:c.990G>A p.Val330= p.V330= ENST00000381249 NM_020905.3 330 gtG/gtA 0 +NT5E UCSF GRCh37 6 86195118 86195118 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 49 32 143 0 ENST00000257770.3:c.917A>G p.Asn306Ser p.N306S ENST00000257770 NM_002526.3 306 aAt/aGt 0 +NTRK3 UCSF GRCh37 15 88678426 88678426 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 163 44 235 0 ENST00000360948.2:c.1110C>T p.His370= p.H370= ENST00000360948 NM_001012338.2 370 caC/caT 0 +NTSR2 UCSF GRCh37 2 11798712 11798712 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 42 186 0 ENST00000306928.5:c.1126C>T p.Leu376= p.L376= ENST00000306928 NM_012344.3 376 Ctg/Ttg 0 +NUDT17 UCSF GRCh37 1 145586887 145586887 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 208 58 262 0 ENST00000334513.5:c.801G>A p.Met267Ile p.M267I ENST00000334513 NM_001012758.2 267 atG/atA 0 +NUDT9 UCSF GRCh37 4 88356236 88356236 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 53 56 142 0 ENST00000302174.4:c.211C>T p.Pro71Ser p.P71S ENST00000302174 NM_024047.4 71 Cca/Tca 0 +NUMA1 UCSF GRCh37 11 71734170 71734170 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 148 41 196 0 ENST00000393695.3:c.232C>T p.Pro78Ser p.P78S ENST00000393695 NM_006185.2 78 Cca/Tca 0 +NUMB UCSF GRCh37 14 73750804 73750804 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 87 27 194 0 ENST00000355058.3:c.934C>T p.Pro312Ser p.P312S ENST00000355058 312 Ccc/Tcc 0 +NUP133 UCSF GRCh37 1 229623317 229623317 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 139 30 158 0 ENST00000261396.3:c.1238C>T p.Ser413Leu p.S413L ENST00000261396 NM_018230.2 413 tCa/tTa 0 +NUP188 UCSF GRCh37 9 131741577 131741577 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 172 22 170 0 ENST00000372577.2:c.1240C>T p.Pro414Ser p.P414S ENST00000372577 NM_015354.2 414 Cct/Tct 0 +NUP188 UCSF GRCh37 9 131721310 131721310 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 72 10 81 0 ENST00000372577.2:c.482G>A p.Cys161Tyr p.C161Y ENST00000372577 NM_015354.2 161 tGt/tAt 0 +NUP214 UCSF GRCh37 9 134064441 134064441 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 20 136 0 ENST00000359428.5:c.3497G>A p.Gly1166Glu p.G1166E ENST00000359428 NM_005085.3 1166 gGg/gAg 0 +NUP93 UCSF GRCh37 16 56863004 56863004 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 143 45 154 0 ENST00000308159.5:c.910C>T p.Pro304Ser p.P304S ENST00000308159 NM_014669.4 304 Ccc/Tcc 0 +NWD1 UCSF GRCh37 19 16875883 16875883 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 45 27 98 0 ENST00000552788.1:c.2290G>A p.Gly764Ser p.G764S ENST00000552788 764 Ggc/Agc 0 +OBSCN UCSF GRCh37 1 228520590 228520590 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 124 37 210 0 ENST00000422127.1:c.15682G>A p.Asp5228Asn p.D5228N ENST00000422127 NM_001098623.2 5228 Gat/Aat 0 +OBSL1 UCSF GRCh37 2 220430123 220430123 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 201 55 439 0 ENST00000404537.1:c.2248T>C p.Tyr750His p.Y750H ENST00000404537 NM_015311.2 750 Tac/Cac 0 +ODZ1 UCSF GRCh37 X 123519885 123519885 + synonymous_variant Silent SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 80 46 121 0 ENST00000371130.3:c.5697G>T p.Arg1899= p.R1899= ENST00000371130 NM_014253.3 1899 cgG/cgT 0 +OLFM1 UCSF GRCh37 9 137967582 137967582 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 13 6 22 0 ENST00000252854.4:c.30C>T p.Asp10= p.D10= ENST00000252854 NM_014279.4 10 gaC/gaT 0 +OR14J1 UCSF GRCh37 6 29275388 29275388 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 255 47 181 0 ENST00000377160.2:c.922C>T p.Leu308Phe p.L308F ENST00000377160 NM_030946.1 308 Ctt/Ttt 0 +OR1G1 UCSF GRCh37 17 3030177 3030177 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 61 173 0 ENST00000328890.2:c.669G>A p.Ser223= p.S223= ENST00000328890 NM_003555.1 223 tcG/tcA 0 +OR2B6 UCSF GRCh37 6 27925897 27925897 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 242 28 151 0 ENST00000244623.1:c.879G>A p.Arg293= p.R293= ENST00000244623 NM_012367.1 293 agG/agA 0 +OR51I2 UCSF GRCh37 11 5474787 5474787 + synonymous_variant Silent SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 22 64 155 0 ENST00000341449.2:c.69T>C p.Ser23= p.S23= ENST00000341449 NM_001004754.2 23 tcT/tcC 0 +OR52B4 UCSF GRCh37 11 4389013 4389013 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 42 39 141 0 ENST00000408920.2:c.513C>T p.Cys171= p.C171= ENST00000408920 NM_001005161.3 171 tgC/tgT 0 +OR5AS1 UCSF GRCh37 11 55798225 55798225 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 223 57 252 0 ENST00000313555.1:c.331G>A p.Glu111Lys p.E111K ENST00000313555 NM_001001921.1 111 Gag/Aag 0 +OR5B12 UCSF GRCh37 11 58206872 58206872 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 128 25 147 1 ENST00000302572.2:c.753G>A p.Gly251= p.G251= ENST00000302572 NM_001004733.2 251 ggG/ggA 0 +OR5K3 UCSF GRCh37 3 98110426 98110426 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 60 12 43 0 ENST00000383695.1:c.917G>A p.Arg306Lys p.R306K ENST00000383695 NM_001005516.1 306 aGa/aAa 0 +OR8B4 UCSF GRCh37 11 124293998 124293998 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 51 23 133 0 ENST00000356130.3:c.770C>T p.Thr257Ile p.T257I ENST00000356130 NM_001005196.1 257 aCc/aTc 0 +OR8J1 UCSF GRCh37 11 56128341 56128341 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 168 46 183 0 ENST00000303039.3:c.619G>A p.Val207Met p.V207M ENST00000303039 NM_001005205.2 207 Gtg/Atg 0 +ORC1 UCSF GRCh37 1 52854139 52854139 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 280 33 370 0 ENST00000371566.1:c.1358C>T p.Thr453Ile p.T453I ENST00000371566 453 aCc/aTc 0 +OSGIN2 UCSF GRCh37 8 90937737 90937737 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 27 92 0 ENST00000297438.2:c.1495G>A p.Gly499Arg p.G499R ENST00000297438 NM_004337.2 499 Gga/Aga 0 +OTOGL UCSF GRCh37 12 80645976 80645976 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 262 35 424 0 ENST00000547103.1:c.1253C>T p.Pro418Leu p.P418L ENST00000547103 418 cCa/cTa 0 +OTOS UCSF GRCh37 2 241078726 241078726 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 129 18 185 0 ENST00000319460.1:c.131C>T p.Thr44Ile p.T44I ENST00000319460 NM_148961.3 44 aCc/aTc 0 +OVCH1 UCSF GRCh37 12 29630283 29630283 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 496 106 518 1 ENST00000318184.5:c.1237T>C p.Ser413Pro p.S413P ENST00000318184 NM_183378.2 413 Tca/Cca 0 +OXA1L UCSF GRCh37 14 23240692 23240692 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 212 62 327 0 ENST00000285848.5:c.1413G>A p.Lys471= p.K471= ENST00000285848 NM_005015.3 471 aaG/aaA 0 +P2RY12 UCSF GRCh37 3 151055634 151055634 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 138 41 159 0 ENST00000302632.3:c.1000G>A p.Gly334Ser p.G334S ENST00000302632 NM_022788.4 334 Ggt/Agt 0 +P2RY12 UCSF GRCh37 3 151056491 151056491 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 97 19 89 0 ENST00000302632.3:c.143G>A p.Arg48Lys p.R48K ENST00000302632 NM_022788.4 48 aGg/aAg 0 +PACSIN3 UCSF GRCh37 11 47204082 47204082 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 55 41 159 0 ENST00000298838.6:c.83G>A p.Arg28Gln p.R28Q ENST00000298838 NM_016223.4 28 cGg/cAg 0 +PADI1 UCSF GRCh37 1 17563920 17563920 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 80 25 128 0 ENST00000375471.4:c.1425G>A p.Glu475= p.E475= ENST00000375471 NM_013358.2 475 gaG/gaA 0 +PAH UCSF GRCh37 12 103306658 103306658 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 100 38 174 0 ENST00000553106.1:c.79G>C p.Asp27His p.D27H ENST00000553106 NM_000277.1 27 Gac/Cac 0 +PAPPA2 UCSF GRCh37 1 176525700 176525700 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 291 66 376 1 ENST00000367662.3:c.242C>T p.Pro81Leu p.P81L ENST00000367662 NM_020318.2 81 cCc/cTc 0 +PAPSS2 UCSF GRCh37 10 89503288 89503288 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 124 18 242 0 ENST00000361175.4:c.1366G>A p.Asp456Asn p.D456N ENST00000361175 NM_004670.3 456 Gac/Aac 0 +PC UCSF GRCh37 11 66620748 66620748 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 135 16 175 0 ENST00000393955.2:c.1475C>T p.Pro492Leu p.P492L ENST00000393955 NM_022172.2 492 cCt/cTt 0 +PCDHB13 UCSF GRCh37 5 140595033 140595033 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 149 99 537 0 ENST00000341948.4:c.1338C>T p.Asp446= p.D446= ENST00000341948 NM_018933.2 446 gaC/gaT 0 +PCDP1 UCSF GRCh37 2 120362788 120362788 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 60 13 114 0 ENST00000413369.3:c.1056G>A p.Thr352= p.T352= ENST00000413369 NM_001271049.1 352 acG/acA 0 +PCGF5 UCSF GRCh37 10 93038059 93038059 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 62 17 101 0 ENST00000336126.5:c.757A>G p.Ile253Val p.I253V ENST00000336126 NM_032373.4 253 Att/Gtt 0 +PCSK2 UCSF GRCh37 20 17208024 17208024 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 53 41 106 0 ENST00000262545.2:c.74C>A p.Ala25Asp p.A25D ENST00000262545 NM_002594.3 25 gCt/gAt 0 +PDE11A UCSF GRCh37 2 178576529 178576529 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 35 11 84 0 ENST00000286063.6:c.2121C>T p.Asp707= p.D707= ENST00000286063 NM_016953.3 707 gaC/gaT 0 +PDGFRA UCSF GRCh37 4 55131142 55131142 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 253 689 207 0 ENST00000257290.5:c.685G>A p.Glu229Lys p.E229K ENST00000257290 NM_006206.4 229 Gaa/Aaa 0 +PDGFRB UCSF GRCh37 5 149501589 149501589 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 53 16 134 0 ENST00000261799.4:c.2198C>T p.Thr733Ile p.T733I ENST00000261799 NM_002609.3 733 aCc/aTc 0 +PDPR UCSF GRCh37 16 70176162 70176162 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 247 33 310 0 ENST00000288050.4:c.1341C>T p.Pro447= p.P447= ENST00000288050 NM_017990.3 447 ccC/ccT 0 +PEAK1 UCSF GRCh37 15 77450873 77450873 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 120 33 152 0 ENST00000312493.4:c.3303C>T p.Asn1101= p.N1101= ENST00000312493 NM_024776.3 1101 aaC/aaT 0 +PENK UCSF GRCh37 8 57354046 57354046 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 175 67 228 0 ENST00000314922.3:c.589C>T p.Pro197Ser p.P197S ENST00000314922 NM_006211.3 197 Ccc/Tcc 0 +PER3 UCSF GRCh37 1 7886742 7886742 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 59 25 99 0 ENST00000361923.2:c.2136G>A p.Arg712= p.R712= ENST00000361923 NM_016831.1 712 agG/agA 0 +PEX5 UCSF GRCh37 12 7360673 7360673 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 19 110 0 ENST00000420616.2:c.1178G>A p.Arg393Gln p.R393Q ENST00000420616 NM_001131025.1 393 cGg/cAg 0 +PFAS UCSF GRCh37 17 8168739 8168739 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 142 44 224 0 ENST00000314666.6:c.2414C>T p.Ser805Phe p.S805F ENST00000314666 NM_012393.2 805 tCc/tTc 0 +PFAS UCSF GRCh37 17 8172160 8172160 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 55 18 90 0 ENST00000314666.6:c.3692G>A p.Ser1231Asn p.S1231N ENST00000314666 NM_012393.2 1231 aGt/aAt 0 +PFKFB2 UCSF GRCh37 1 207240875 207240875 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 122 41 177 0 ENST00000367080.3:c.664G>A p.Gly222Ser p.G222S ENST00000367080 NM_006212.2 222 Ggc/Agc 0 +PFKFB4 UCSF GRCh37 3 48576744 48576744 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 36 11 65 0 ENST00000232375.3:c.454-1G>A p.X152_splice ENST00000232375 NM_004567.2 0 +PGP UCSF GRCh37 16 2263816 2263816 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 179 41 243 0 ENST00000333503.7:c.879G>A p.Gln293= p.Q293= ENST00000333503 NM_001042371.2 293 caG/caA 0 +PHF21A UCSF GRCh37 11 45955610 45955610 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 42 5 79 0 ENST00000418153.2:c.1952C>T p.Pro651Leu p.P651L ENST00000418153 651 cCc/cTc 0 +PHF21B UCSF GRCh37 22 45281750 45281750 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 147 48 205 0 ENST00000313237.5:c.1266C>T p.His422= p.H422= ENST00000313237 NM_138415.4 422 caC/caT 0 +PHLDB1 UCSF GRCh37 11 118495696 118495696 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 48 34 168 0 ENST00000361417.2:c.402C>T p.His134= p.H134= ENST00000361417 NM_015157.3 134 caC/caT 0 +PIGT UCSF GRCh37 20 44052855 44052855 + splice_acceptor_variant Splice_Site SNP G G A snp132_rs112243674 P21_Rec Untested WXS Illumina HiSeq 79 24 140 0 ENST00000279036.6:c.1235-1G>A p.X412_splice ENST00000279036 NM_015937.5 0 +PIKFYVE UCSF GRCh37 2 209198074 209198074 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 95 11 142 0 ENST00000264380.4:c.3999G>A p.Trp1333Ter p.W1333* ENST00000264380 NM_015040.3 1333 tgG/tgA 0 +PIWIL2 UCSF GRCh37 8 22171841 22171841 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 34 10 43 0 ENST00000356766.6:c.1990G>A p.Gly664Arg p.G664R ENST00000356766 NM_018068.3 664 Ggg/Agg 0 +PKD1 UCSF GRCh37 16 2153526 2153526 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 248 75 463 0 ENST00000262304.4:c.8532C>T p.Val2844= p.V2844= ENST00000262304 NM_001009944.2 2844 gtC/gtT 0 +PKHD1L1 UCSF GRCh37 8 110498908 110498908 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 551 75 508 0 ENST00000378402.5:c.9738G>A p.Glu3246= p.E3246= ENST00000378402 NM_177531.4 3246 gaG/gaA 0 +PKLR UCSF GRCh37 1 155269984 155269984 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 62 18 79 0 ENST00000342741.4:c.188C>T p.Ala63Val p.A63V ENST00000342741 NM_000298.5 63 gCt/gTt 0 +PKN2 UCSF GRCh37 1 89294219 89294219 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 16 75 0 ENST00000370521.3:c.2475C>T p.Ala825= p.A825= ENST00000370521 NM_006256.2 825 gcC/gcT 0 +PLEKHG2 UCSF GRCh37 19 39904836 39904836 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 17 6 30 0 ENST00000425673.1:c.109+1G>A p.X37_splice ENST00000425673 0 +PLEKHG3 UCSF GRCh37 14 65194574 65194574 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 24 10 51 0 ENST00000394691.1:c.225C>T p.Leu75= p.L75= ENST00000394691 75 ctC/ctT 0 +PLEKHM1 UCSF GRCh37 17 43552712 43552712 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 154 40 268 0 ENST00000430334.3:c.677C>T p.Ser226Phe p.S226F ENST00000430334 NM_014798.2 226 tCt/tTt 0 +PLOD1 UCSF GRCh37 1 12032969 12032969 + missense_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 119 25 184 0 ENST00000196061.4:c.1943A>T p.Asp648Val p.D648V ENST00000196061 NM_000302.3 648 gAt/gTt 0 +PLSCR3 UCSF GRCh37 17 7296919 7296919 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 159 40 202 0 ENST00000535512.1:c.243+1G>A p.X81_splice ENST00000535512 0 +PLXNA1 UCSF GRCh37 3 126741603 126741603 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 170 39 301 2 ENST00000393409.2:c.4304C>T p.Ser1435Leu p.S1435L ENST00000393409 NM_032242.3 1435 tCg/tTg 0 +PML UCSF GRCh37 15 74290735 74290735 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 20 118 0 ENST00000268058.3:c.520G>A p.Val174Met p.V174M ENST00000268058 NM_033238.2 174 Gtg/Atg 0 +POLI UCSF GRCh37 18 51800296 51800296 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 115 47 174 0 ENST00000579534.1:c.242G>A p.Gly81Glu p.G81E ENST00000579534 NM_007195.2 81 gGg/gAg 0 +POLK UCSF GRCh37 5 74892598 74892598 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 19 74 0 ENST00000241436.4:c.2080G>A p.Glu694Lys p.E694K ENST00000241436 NM_016218.2 694 Gaa/Aaa 0 +POLN UCSF GRCh37 4 2082740 2082740 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 139 31 191 0 ENST00000382865.1:c.2332C>T p.Leu778= p.L778= ENST00000382865 NM_181808.2 778 Ctg/Ttg 0 +PON2 UCSF GRCh37 7 95039262 95039262 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 157 46 277 0 ENST00000222572.3:c.646G>A p.Ala216Thr p.A216T ENST00000222572 216 Gca/Aca 0 +POSTN UCSF GRCh37 13 38161957 38161957 + splice_donor_variant Splice_Site SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 40 33 96 0 ENST00000379747.4:c.606+2T>C p.X202_splice ENST00000379747 NM_006475.2 0 +PPFIA4 UCSF GRCh37 1 203022984 203022984 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 21 8 30 0 ENST00000447715.2:c.1693G>A p.Val565Ile p.V565I ENST00000447715 565 Gtc/Atc 0 +PPFIBP1 UCSF GRCh37 12 27841986 27841986 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 216 95 245 0 ENST00000318304.8:c.2553G>T p.Gln851His p.Q851H ENST00000318304 NM_177444.2 851 caG/caT 0 +PPIB UCSF GRCh37 15 64448950 64448950 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 268 96 434 0 ENST00000300026.3:c.502G>A p.Val168Met p.V168M ENST00000300026 NM_000942.4 168 Gtg/Atg 0 +PPM1B UCSF GRCh37 2 44445214 44445214 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 54 22 73 0 ENST00000282412.4:c.1073G>A p.Gly358Asp p.G358D ENST00000282412 NM_002706.4 358 gGc/gAc 0 +PPP1R13L UCSF GRCh37 19 45889151 45889151 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 6 37 0 ENST00000360957.5:c.2012C>T p.Ala671Val p.A671V ENST00000360957 NM_006663.3 671 gCc/gTc 0 +PPP2R1A UCSF GRCh37 19 52715981 52715981 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 131 47 184 0 ENST00000322088.6:c.546G>A p.Arg182= p.R182= ENST00000322088 NM_014225.5 182 cgG/cgA 0 +PPP2R2C UCSF GRCh37 4 6325083 6325083 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 93 23 152 0 ENST00000382599.4:c.1290C>T p.Ala430= p.A430= ENST00000382599 430 gcC/gcT 0 +PPWD1 UCSF GRCh37 5 64867978 64867978 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 142 39 162 0 ENST00000261308.5:c.834G>A p.Lys278= p.K278= ENST00000261308 NM_001278927.1 278 aaG/aaA 0 +PRG2 UCSF GRCh37 11 57156716 57156716 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 127 26 189 0 ENST00000311862.5:c.133G>A p.Glu45Lys p.E45K ENST00000311862 NM_002728.4 45 Gag/Aag 0 +PRKCB UCSF GRCh37 16 24135240 24135240 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 174 58 357 0 ENST00000321728.7:c.1003G>A p.Asp335Asn p.D335N ENST00000321728 NM_212535.2 335 Gac/Aac 0 +PRKD1 UCSF GRCh37 14 30194858 30194858 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 90 40 177 0 ENST00000331968.5:c.287G>A p.Gly96Glu p.G96E ENST00000331968 NM_002742.2 96 gGa/gAa 0 +PRKDC UCSF GRCh37 8 48792051 48792051 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 93 14 93 0 ENST00000314191.2:c.5232+1G>A p.X1744_splice ENST00000314191 NM_006904.6 0 +PRKDC UCSF GRCh37 8 48842573 48842573 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 122 32 131 0 ENST00000314191.2:c.1893-1G>A p.X631_splice ENST00000314191 NM_006904.6 0 +PRODH UCSF GRCh37 22 18910629 18910629 + missense_variant,splice_region_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 131 41 201 0 ENST00000357068.6:c.731T>C p.Leu244Pro p.L244P ENST00000357068 NM_016335.4 244 cTg/cCg 0 +PRPF40B UCSF GRCh37 12 50027730 50027730 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 18 115 0 ENST00000380281.1:c.601C>T p.Pro201Ser p.P201S ENST00000380281 201 Ccc/Tcc 0 +PRPF40B UCSF GRCh37 12 50035712 50035712 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 22 109 0 ENST00000380281.1:c.1723G>A p.Val575Met p.V575M ENST00000380281 575 Gtg/Atg 0 +PRR12 UCSF GRCh37 19 50098109 50098109 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 15 5 20 0 ENST00000418929.2:c.517C>T p.Pro173Ser p.P173S ENST00000418929 NM_020719.1 173 Ccc/Tcc 0 +PRRC2C UCSF GRCh37 1 171510733 171510733 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.0061,snp132_rs74122867 P21_Rec Untested WXS Illumina HiSeq 192 45 241 0 ENST00000338920.4:c.4122G>A p.Gln1374= p.Q1374= ENST00000338920 NM_015172.3 1374 caG/caA 0 +PRSS3 UCSF GRCh37 9 33797843 33797843 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 418 92 659 0 ENST00000361005.5:c.388C>T p.Leu130= p.L130= ENST00000361005 NM_007343.3 130 Ctg/Ttg 0 +PSAPL1 UCSF GRCh37 4 7435437 7435437 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 148 47 233 0 ENST00000319098.4:c.1170G>A p.Glu390= p.E390= ENST00000319098 NM_001085382.1 390 gaG/gaA 0 +PSD3 UCSF GRCh37 8 18725432 18725432 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 231 62 310 0 ENST00000440756.2:c.1386G>A p.Glu462= p.E462= ENST00000440756 462 gaG/gaA 0 +PSMB1 UCSF GRCh37 6 170844403 170844403 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 63 33 213 0 ENST00000262193.6:c.631G>A p.Ala211Thr p.A211T ENST00000262193 NM_002793.3 211 Gct/Act 0 +PTCH1 UCSF GRCh37 9 98209333 98209333 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 109 27 174 0 ENST00000331920.6:c.4205C>T p.Pro1402Leu p.P1402L ENST00000331920 NM_000264.3 1402 cCt/cTt 0 +PTCHD2 UCSF GRCh37 1 11561820 11561820 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 25 14 53 0 ENST00000294484.6:c.771C>T p.Asp257= p.D257= ENST00000294484 NM_020780.1 257 gaC/gaT 0 +PTPLAD2 UCSF GRCh37 9 21026605 21026605 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 95 37 200 0 ENST00000495827.2:c.260G>A p.Arg87Lys p.R87K ENST00000495827 NM_001010915.3 87 aGg/aAg 0 +PTPRN2 UCSF GRCh37 7 157926724 157926724 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 80 24 166 0 ENST00000389418.4:c.1201G>A p.Gly401Ser p.G401S ENST00000389418 NM_002847.3 401 Ggc/Agc 0 +PUM2 UCSF GRCh37 2 20478577 20478577 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 114 57 218 0 ENST00000338086.5:c.1724G>A p.Gly575Asp p.G575D ENST00000338086 NM_015317.1 575 gGc/gAc 0 +PXDN UCSF GRCh37 2 1677534 1677534 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 302 93 630 0 ENST00000252804.4:c.899G>A p.Gly300Glu p.G300E ENST00000252804 NM_012293.1 300 gGg/gAg 0 +QSOX2 UCSF GRCh37 9 139108532 139108532 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 70 21 102 0 ENST00000358701.5:c.1123G>A p.Glu375Lys p.E375K ENST00000358701 NM_181701.3 375 Gag/Aag 0 +R3HCC1 UCSF GRCh37 8 23147752 23147752 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 18 5 16 0 ENST00000411463.1:c.742C>T p.Leu248= p.L248= ENST00000411463 248 Ctg/Ttg 0 +RAB3GAP2 UCSF GRCh37 1 220364547 220364547 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 99 36 159 0 ENST00000358951.2:c.1350C>T p.Ser450= p.S450= ENST00000358951 NM_012414.3 450 tcC/tcT 0 +RABGAP1L UCSF GRCh37 1 174957826 174957826 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 19 82 0 ENST00000325589.5:c.775G>A p.Gly259Ser p.G259S ENST00000325589 259 Ggt/Agt 0 +RAD17 UCSF GRCh37 5 68692336 68692336 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 51 14 61 0 ENST00000380774.3:c.1568C>T p.Pro523Leu p.P523L ENST00000380774 NM_133339.2 523 cCc/cTc 0 +RAD21 UCSF GRCh37 8 117866648 117866648 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 309 38 266 0 ENST00000297338.2:c.997G>A p.Asp333Asn p.D333N ENST00000297338 NM_006265.2 333 Gat/Aat 0 +RAD51 UCSF GRCh37 15 40991018 40991018 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 32 155 0 ENST00000267868.3:c.62G>A p.Gly21Asp p.G21D ENST00000267868 NM_002875.4 21 gGc/gAc 0 +RAD54L2 UCSF GRCh37 3 51672310 51672310 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 136 50 150 0 ENST00000409535.2:c.1833C>T p.Pro611= p.P611= ENST00000409535 NM_015106.2 611 ccC/ccT 0 +RALGAPB UCSF GRCh37 20 37137727 37137727 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 50 246 0 ENST00000262879.6:c.748C>T p.Arg250Cys p.R250C ENST00000262879 250 Cgc/Tgc 0 +RALGDS UCSF GRCh37 9 135974021 135974021 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 13 127 0 ENST00000372050.3:c.2698C>T p.Pro900Ser p.P900S ENST00000372050 NM_006266.3 900 Cct/Tct 0 +RANBP3 UCSF GRCh37 19 5923259 5923259 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 98 15 139 0 ENST00000340578.6:c.1155G>A p.Leu385= p.L385= ENST00000340578 NM_007322.2 385 ttG/ttA 0 +RAP1GAP2 UCSF GRCh37 17 2908700 2908700 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 247 158 544 0 ENST00000254695.8:c.1238G>T p.Gly413Val p.G413V ENST00000254695 NM_015085.4 413 gGt/gTt 0 +RAPGEF5 UCSF GRCh37 7 22349610 22349610 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 144 64 270 0 ENST00000344041.6:c.30G>A p.Leu10= p.L10= ENST00000344041 NM_012294.3 10 ctG/ctA 0 +RASGRF1 UCSF GRCh37 15 79382719 79382719 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 246 61 324 0 ENST00000419573.3:c.122C>T p.Thr41Ile p.T41I ENST00000419573 NM_002891.4 41 aCc/aTc 0 +RASGRF1 UCSF GRCh37 15 79298560 79298560 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 37 240 0 ENST00000419573.3:c.2082C>T p.Ile694= p.I694= ENST00000419573 NM_002891.4 694 atC/atT 0 +RBAK UCSF GRCh37 7 5104026 5104026 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 132 56 231 0 ENST00000353796.3:c.939G>A p.Glu313= p.E313= ENST00000353796 NM_001204456.1 313 gaG/gaA 0 +RBM12 UCSF GRCh37 20 34241916 34241916 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 37 160 0 ENST00000359646.1:c.1329C>T p.Asn443= p.N443= ENST00000359646 443 aaC/aaT 0 +RBM15 UCSF GRCh37 1 110884780 110884780 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 145 55 201 0 ENST00000369784.3:c.2753G>A p.Gly918Glu p.G918E ENST00000369784 NM_022768.4 918 gGg/gAg 0 +RBM17 UCSF GRCh37 10 6151953 6151953 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 214 33 172 0 ENST00000379888.4:c.567C>T p.Pro189= p.P189= ENST00000379888 NM_032905.4 189 ccC/ccT 0 +RBM26 UCSF GRCh37 13 79928639 79928639 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 8 123 0 ENST00000438737.2:c.1921G>A p.Gly641Ser p.G641S ENST00000438737 NM_001286631.1 641 Ggt/Agt 0 +RBMS3 UCSF GRCh37 3 29476270 29476270 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 37 182 1 ENST00000383767.2:c.112C>A p.Pro38Thr p.P38T ENST00000383767 38 Ccc/Acc 0 +RC3H2 UCSF GRCh37 9 125659702 125659702 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 96 25 133 0 ENST00000357244.2:c.87C>T p.Ile29= p.I29= ENST00000357244 NM_001100588.1 29 atC/atT 0 +RCSD1 UCSF GRCh37 1 167666688 167666688 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 19 4 31 0 ENST00000367854.3:c.827C>T p.Pro276Leu p.P276L ENST00000367854 NM_052862.3 276 cCg/cTg 0 +REV1 UCSF GRCh37 2 100024589 100024589 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 148 18 174 0 ENST00000258428.3:c.2350G>A p.Val784Ile p.V784I ENST00000258428 NM_001037872.1 784 Gta/Ata 0 +REV3L UCSF GRCh37 6 111695087 111695087 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 107 80 244 0 ENST00000358835.3:c.4471G>A p.Val1491Ile p.V1491I ENST00000358835 1491 Gta/Ata 0 +RG9MTD3 UCSF GRCh37 9 37770683 37770683 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 56 17 91 0 ENST00000297994.3:c.667G>A p.Asp223Asn p.D223N ENST00000297994 NM_144964.2 223 Gat/Aat 0 +RGS12 UCSF GRCh37 4 3318901 3318901 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 177 45 247 1 ENST00000336727.3:c.1004C>T p.Thr335Ile p.T335I ENST00000336727 NM_002926.3 335 aCt/aTt 0 +RGS14 UCSF GRCh37 5 176795777 176795777 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 15 59 136 0 ENST00000408923.3:c.909C>T p.Tyr303= p.Y303= ENST00000408923 NM_006480.4 303 taC/taT 0 +RHAG UCSF GRCh37 6 49604443 49604443 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0042,snp132_rs114042395 P21_Rec Untested WXS Illumina HiSeq 368 52 259 0 ENST00000371175.4:c.83C>T p.Thr28Met p.T28M ENST00000371175 NM_000324.2 28 aCg/aTg 0 +RHBDF2 UCSF GRCh37 17 74470598 74470598 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 27 113 0 ENST00000313080.4:c.1408G>A p.Gly470Arg p.G470R ENST00000313080 NM_024599.5 470 Ggg/Agg 0 +RHOB UCSF GRCh37 2 20647261 20647261 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 34 15 84 0 ENST00000272233.4:c.35G>A p.Gly12Asp p.G12D ENST00000272233 NM_004040.2 12 gGc/gAc 0 +RHOT2 UCSF GRCh37 16 722944 722944 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 36 153 0 ENST00000315082.4:c.1544G>A p.Gly515Glu p.G515E ENST00000315082 NM_138769.2 515 gGg/gAg 0 +RIMS1 UCSF GRCh37 6 73110251 73110251 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 119 35 332 0 ENST00000521978.1:c.4914G>A p.Val1638= p.V1638= ENST00000521978 NM_014989.5 1638 gtG/gtA 0 +RIN2 UCSF GRCh37 20 19956118 19956118 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 141 32 259 0 ENST00000255006.6:c.1596G>A p.Arg532= p.R532= ENST00000255006 NM_018993.3 532 agG/agA 0 +RNF19B UCSF GRCh37 1 33407982 33407982 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 37 132 0 ENST00000373456.7:c.1484C>T p.Thr495Ile p.T495I ENST00000373456 NM_153341.2 495 aCt/aTt 0 +RNF20 UCSF GRCh37 9 104303258 104303258 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 31 134 0 ENST00000389120.3:c.628+1G>A p.X210_splice ENST00000389120 NM_019592.6 0 +RNF212 UCSF GRCh37 4 1087248 1087248 + intron_variant Intron SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 53 7 66 0 ENST00000433731.2:c.247-2622G>A *83* ENST00000433731 0 +RNF26 UCSF GRCh37 11 119206973 119206973 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 91 12 172 0 ENST00000311413.4:c.1141G>A p.Val381Ile p.V381I ENST00000311413 NM_032015.4 381 Gtc/Atc 0 +RNF43 UCSF GRCh37 17 56434896 56434896 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 118 40 186 1 ENST00000407977.2:c.2241G>A p.Trp747Ter p.W747* ENST00000407977 747 tgG/tgA 0 +RNGTT UCSF GRCh37 6 89673110 89673110 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 21 9 59 0 ENST00000369485.4:c.19C>T p.Pro7Ser p.P7S ENST00000369485 NM_003800.3 7 Ccg/Tcg 0 +RNMTL1 UCSF GRCh37 17 686449 686449 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 149 26 173 0 ENST00000304478.4:c.441C>T p.Ser147= p.S147= ENST00000304478 NM_018146.2 147 agC/agT 0 +ROBO2 UCSF GRCh37 3 77638066 77638066 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 114 82 181 0 ENST00000461745.1:c.2665G>A p.Gly889Arg p.G889R ENST00000461745 NM_002942.4 889 Gga/Aga 0 +ROR2 UCSF GRCh37 9 94487067 94487067 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 109 24 171 0 ENST00000375708.3:c.1709C>T p.Pro570Leu p.P570L ENST00000375708 NM_004560.3 570 cCg/cTg 0 +RPP25 UCSF GRCh37 15 75248436 75248436 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 23 9 23 0 ENST00000322177.5:c.489G>A p.Pro163= p.P163= ENST00000322177 NM_017793.2 163 ccG/ccA 0 +RREB1 UCSF GRCh37 6 7248786 7248786 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 20 148 0 ENST00000349384.6:c.4649C>T p.Thr1550Ile p.T1550I ENST00000349384 NM_001003698.3 1550 aCc/aTc 0 +RRM2 UCSF GRCh37 2 10263567 10263567 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 45 18 98 0 ENST00000304567.5:c.228C>T p.Asn76= p.N76= ENST00000304567 NM_001034.3 76 aaC/aaT 0 +RRP1B UCSF GRCh37 21 45103245 45103245 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 98 13 94 0 ENST00000340648.4:c.882C>T p.Pro294= p.P294= ENST00000340648 NM_015056.2 294 ccC/ccT 0 +RRP36 UCSF GRCh37 6 42996950 42996950 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 515 61 297 0 ENST00000244496.5:c.764C>T p.Pro255Leu p.P255L ENST00000244496 NM_033112.2 255 cCt/cTt 0 +RTN4RL2 UCSF GRCh37 11 57235467 57235467 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 112 39 182 0 ENST00000335099.3:c.417C>T p.Tyr139= p.Y139= ENST00000335099 NM_178570.2 139 taC/taT 0 +RUNDC1 UCSF GRCh37 17 41143444 41143444 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 132 34 218 0 ENST00000361677.1:c.1553C>T p.Thr518Ile p.T518I ENST00000361677 NM_173079.2 518 aCa/aTa 0 +RYR3 UCSF GRCh37 15 34049710 34049710 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 53 11 85 0 ENST00000389232.4:c.8618G>A p.Ser2873Asn p.S2873N ENST00000389232 NM_001036.3 2873 aGt/aAt 0 +SAFB2 UCSF GRCh37 19 5594077 5594077 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 11 4 25 0 ENST00000252542.4:c.2032G>A p.Glu678Lys p.E678K ENST00000252542 NM_014649.2 678 Gag/Aag 0 +SAMD8 UCSF GRCh37 10 76936330 76936330 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 33 194 0 ENST00000542569.1:c.1128G>A p.Arg376= p.R376= ENST00000542569 NM_144660.2 376 agG/agA 0 +SAP130 UCSF GRCh37 2 128750879 128750879 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 185 51 280 0 ENST00000259235.3:c.1437G>A p.Pro479= p.P479= ENST00000259235 NM_024545.3 479 ccG/ccA 0 +SARS UCSF GRCh37 1 109777933 109777933 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 55 234 0 ENST00000234677.2:c.849G>A p.Glu283= p.E283= ENST00000234677 NM_006513.3 283 gaG/gaA 0 +SART1 UCSF GRCh37 11 65746346 65746346 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 146 26 187 0 ENST00000312397.5:c.2345C>T p.Pro782Leu p.P782L ENST00000312397 NM_005146.4 782 cCc/cTc 0 +SART1 UCSF GRCh37 11 65743865 65743865 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 8 35 0 ENST00000312397.5:c.1573-1G>A p.X525_splice ENST00000312397 NM_005146.4 0 +SBNO1 UCSF GRCh37 12 123798194 123798194 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 32 18 45 0 ENST00000420886.2:c.3193C>T p.Pro1065Ser p.P1065S ENST00000420886 NM_001167856.1 1065 Cca/Tca 0 +SCAF11 UCSF GRCh37 12 46357889 46357889 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 23 7 30 0 ENST00000369367.3:c.61+1G>A p.X21_splice ENST00000369367 NM_004719.2 0 +SCAF4 UCSF GRCh37 21 33058004 33058004 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 53 62 0 ENST00000286835.7:c.2086C>T p.Gln696Ter p.Q696* ENST00000286835 NM_020706.2 696 Cag/Tag 0 +SCAF8 UCSF GRCh37 6 155145444 155145444 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 45 221 0 ENST00000367178.3:c.2003C>T p.Pro668Leu p.P668L ENST00000367178 NM_014892.3 668 cCt/cTt 0 +SCARA3 UCSF GRCh37 8 27516386 27516386 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 64 9 95 0 ENST00000301904.3:c.699G>T p.Trp233Cys p.W233C ENST00000301904 NM_016240.2 233 tgG/tgT 0 +SCN11A UCSF GRCh37 3 38924723 38924723 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 13 136 0 ENST00000302328.3:c.3219+1G>A p.X1073_splice ENST00000302328 NM_014139.2 0 +SCN3B UCSF GRCh37 11 123513277 123513277 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 87 13 190 0 ENST00000299333.3:c.322C>T p.Leu108Phe p.L108F ENST00000299333 NM_001040151.1 108 Ctc/Ttc 0 +SCNM1 UCSF GRCh37 1 151139625 151139625 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 251 58 314 0 ENST00000368905.4:c.240G>A p.Gln80= p.Q80= ENST00000368905 NM_024041.3 80 caG/caA 0 +SCPEP1 UCSF GRCh37 17 55078335 55078335 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 187 58 266 0 ENST00000262288.3:c.1114C>T p.Leu372Phe p.L372F ENST00000262288 NM_021626.2 372 Ctc/Ttc 0 +SCUBE2 UCSF GRCh37 11 9052337 9052337 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 99 41 270 0 ENST00000520467.1:c.2138G>A p.Gly713Glu p.G713E ENST00000520467 NM_020974.2 713 gGa/gAa 0 +SCYL2 UCSF GRCh37 12 100723044 100723044 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 69 12 77 0 ENST00000360820.2:c.1708G>A p.Val570Met p.V570M ENST00000360820 NM_017988.4 570 Gtg/Atg 0 +SCYL3 UCSF GRCh37 1 169847817 169847817 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 151 39 203 0 ENST00000367770.1:c.309G>A p.Gly103= p.G103= ENST00000367770 103 ggG/ggA 0 +SEMA6A UCSF GRCh37 5 115808768 115808768 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 199 54 225 0 ENST00000343348.6:c.1729+1G>A p.X577_splice ENST00000343348 NM_020796.3 0 +SEMA6A UCSF GRCh37 5 115814408 115814408 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 217 66 292 0 ENST00000343348.6:c.1257C>T p.Arg419= p.R419= ENST00000343348 NM_020796.3 419 cgC/cgT 0 +SERTAD1 UCSF GRCh37 19 40929159 40929159 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 18 3 27 0 ENST00000357949.4:c.295G>A p.Val99Met p.V99M ENST00000357949 NM_013376.3 99 Gtg/Atg 0 +SETD5 UCSF GRCh37 3 9512549 9512549 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 299 61 247 0 ENST00000402198.1:c.3131C>T p.Pro1044Leu p.P1044L ENST00000402198 NM_001080517.1 1044 cCt/cTt 0 +SETD5 UCSF GRCh37 3 9485095 9485095 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 92 14 90 0 ENST00000402198.1:c.1181G>A p.Ser394Asn p.S394N ENST00000402198 NM_001080517.1 394 aGt/aAt 0 +SETD6 UCSF GRCh37 16 58550503 58550503 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 68 22 102 0 ENST00000219315.4:c.598C>T p.Pro200Ser p.P200S ENST00000219315 200 Ccc/Tcc 0 +SF3B3 UCSF GRCh37 16 70601401 70601401 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 106 21 123 1 ENST00000302516.5:c.2914C>T p.Leu972= p.L972= ENST00000302516 NM_012426.4 972 Ctg/Ttg 0 +SFXN2 UCSF GRCh37 10 104491966 104491966 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 62 29 152 0 ENST00000369893.5:c.712C>T p.Pro238Ser p.P238S ENST00000369893 NM_178858.4 238 Cct/Tct 0 +SGOL1 UCSF GRCh37 3 20216193 20216193 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 87 23 112 0 ENST00000263753.4:c.830C>T p.Ser277Phe p.S277F ENST00000263753 NM_001012410.3 277 tCt/tTt 0 +SGSM3 UCSF GRCh37 22 40803205 40803205 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 93 22 126 0 ENST00000248929.9:c.1241G>A p.Gly414Glu p.G414E ENST00000248929 NM_015705.4 414 gGg/gAg 0 +SHANK2 UCSF GRCh37 11 70332736 70332736 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 25 122 0 ENST00000423696.2:c.2525C>T p.Ser842Phe p.S842F ENST00000423696 842 tCc/tTc 0 +SHBG UCSF GRCh37 17 7534144 7534144 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 9 121 0 ENST00000380450.4:c.350C>T p.Thr117Met p.T117M ENST00000380450 NM_001040.3 117 aCg/aTg 0 +SHMT2 UCSF GRCh37 12 57627415 57627415 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 33 166 0 ENST00000328923.3:c.1093C>T p.Leu365= p.L365= ENST00000328923 NM_005412.5 365 Ctg/Ttg 0 +SI UCSF GRCh37 3 164777734 164777734 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 257 77 302 0 ENST00000264382.3:c.1102G>A p.Val368Met p.V368M ENST00000264382 NM_001041.3 368 Gtg/Atg 0 +SIAH3 UCSF GRCh37 13 46358136 46358136 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 23 18 114 0 ENST00000400405.2:c.192C>T p.His64= p.H64= ENST00000400405 NM_198849.2 64 caC/caT 0 +SIDT1 UCSF GRCh37 3 113331041 113331041 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 85 27 99 0 ENST00000264852.4:c.1966G>A p.Asp656Asn p.D656N ENST00000264852 NM_017699.2 656 Gat/Aat 0 +SLC10A2 UCSF GRCh37 13 103698539 103698539 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 48 6 108 0 ENST00000245312.3:c.991G>A p.Glu331Lys p.E331K ENST00000245312 NM_000452.2 331 Gag/Aag 0 +SLC10A4 UCSF GRCh37 4 48490831 48490831 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 79 20 88 0 ENST00000273861.4:c.1189G>A p.Asp397Asn p.D397N ENST00000273861 NM_152679.3 397 Gat/Aat 0 +SLC12A1 UCSF GRCh37 15 48539196 48539196 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0029 P21_Rec Untested WXS Illumina HiSeq 310 199 501 0 ENST00000380993.3:c.1543G>A p.Ala515Thr p.A515T ENST00000380993 NM_000338.2 515 Gca/Aca 0 +SLC12A6 UCSF GRCh37 15 34533453 34533453 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 10 40 0 ENST00000354181.3:c.2248C>A p.Pro750Thr p.P750T ENST00000354181 750 Cca/Aca 0 +SLC17A2 UCSF GRCh37 6 25917232 25917232 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 189 36 141 0 ENST00000265425.3:c.733G>A p.Glu245Lys p.E245K ENST00000265425 245 Gaa/Aaa 0 +SLC24A5 UCSF GRCh37 15 48428997 48428997 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 136 37 146 0 ENST00000341459.3:c.708C>T p.Ala236= p.A236= ENST00000341459 NM_205850.2 236 gcC/gcT 0 +SLC25A14 UCSF GRCh37 X 129506898 129506898 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 126 100 210 0 ENST00000218197.5:c.952G>A p.Glu318Lys p.E318K ENST00000218197 NM_022810.1 318 Gag/Aag 0 +SLC25A25 UCSF GRCh37 9 130869597 130869597 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 147 33 211 0 ENST00000373064.5:c.1284G>A p.Arg428= p.R428= ENST00000373064 NM_052901.4 428 cgG/cgA 0 +SLC26A8 UCSF GRCh37 6 35927270 35927270 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 269 54 195 0 ENST00000355574.2:c.1830C>T p.Phe610= p.F610= ENST00000355574 NM_001193476.1 610 ttC/ttT 0 +SLC27A3 UCSF GRCh37 1 153750305 153750305 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 106 23 175 0 ENST00000368661.3:c.1246G>A p.Val416Met p.V416M ENST00000368661 NM_024330.1 416 Gtg/Atg 0 +SLC28A1 UCSF GRCh37 15 85438637 85438637 + intron_variant Intron SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 62 28 86 0 ENST00000286749.3:c.461+283C>T *154* ENST00000286749 NM_001287762.1 0 +SLC29A4 UCSF GRCh37 7 5340179 5340179 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 162 61 343 0 ENST00000297195.4:c.1336C>T p.Pro446Ser p.P446S ENST00000297195 NM_001040661.1 446 Ccc/Tcc 0 +SLC30A1 UCSF GRCh37 1 211749269 211749269 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 178 48 241 1 ENST00000367001.4:c.985C>T p.Leu329Phe p.L329F ENST00000367001 NM_021194.2 329 Ctt/Ttt 0 +SLC30A6 UCSF GRCh37 2 32445766 32445766 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 68 42 167 0 ENST00000282587.5:c.1370G>A p.Gly457Glu p.G457E ENST00000282587 NM_017964.3 457 gGa/gAa 0 +SLC35G1 UCSF GRCh37 10 95661083 95661083 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 92 18 144 0 ENST00000427197.1:c.934G>A p.Gly312Arg p.G312R ENST00000427197 NM_001134658.1 312 Ggg/Agg 0 +SLC41A2 UCSF GRCh37 12 105199074 105199074 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 259 30 390 1 ENST00000258538.3:c.1578C>T p.His526= p.H526= ENST00000258538 NM_032148.3 526 caC/caT 0 +SLC4A4 UCSF GRCh37 4 72222843 72222843 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 81 54 244 0 ENST00000264485.5:c.669C>T p.Ser223= p.S223= ENST00000264485 NM_001098484.2 223 tcC/tcT 0 +SLC5A6 UCSF GRCh37 2 27423865 27423865 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 62 13 112 0 ENST00000310574.3:c.1764+1G>A p.X588_splice ENST00000310574 NM_021095.2 0 +SLC6A11 UCSF GRCh37 3 10970906 10970906 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 261 43 322 0 ENST00000254488.2:c.1252C>T p.Leu418= p.L418= ENST00000254488 NM_014229.1 418 Ctg/Ttg 0 +SLC6A17 UCSF GRCh37 1 110741056 110741056 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 93 34 134 0 ENST00000331565.4:c.2174C>T p.Ser725Leu p.S725L ENST00000331565 NM_001010898.2 725 tCg/tTg 0 +SLC7A5 UCSF GRCh37 16 87874719 87874719 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 28 154 0 ENST00000261622.4:c.707C>T p.Thr236Ile p.T236I ENST00000261622 NM_003486.5 236 aCc/aTc 0 +SLC9A1 UCSF GRCh37 1 27426843 27426843 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 26 137 0 ENST00000263980.3:c.2403C>T p.His801= p.H801= ENST00000263980 NM_003047.4 801 caC/caT 0 +SLCO1B1 UCSF GRCh37 12 21350030 21350030 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 376 57 275 1 ENST00000256958.2:c.878C>T p.Ser293Leu p.S293L ENST00000256958 NM_006446.4 293 tCa/tTa 0 +SLCO1B7 UCSF GRCh37 12 21201727 21201727 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 178 26 108 0 ENST00000421593.2:c.1076G>T p.Gly359Val p.G359V ENST00000421593 NM_001009562.4 359 gGa/gTa 0 +SLITRK2 UCSF GRCh37 X 144905522 144905522 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 66 42 138 0 ENST00000370490.1:c.1579C>T p.Gln527Ter p.Q527* ENST00000370490 527 Cag/Tag 0 +SMC2 UCSF GRCh37 9 106880459 106880459 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 112 18 133 0 ENST00000286398.7:c.1799C>T p.Pro600Leu p.P600L ENST00000286398 NM_006444.2 600 cCt/cTt 0 +SMG7 UCSF GRCh37 1 183514090 183514090 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 222 36 262 0 ENST00000347615.2:c.2013C>T p.Ile671= p.I671= ENST00000347615 NM_173156.2 671 atC/atT 0 +SMG9 UCSF GRCh37 19 44251951 44251951 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 55 10 53 0 ENST00000270066.6:c.324G>A p.Lys108= p.K108= ENST00000270066 NM_019108.2 108 aaG/aaA 0 +SMOC1 UCSF GRCh37 14 70418989 70418989 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 33 226 0 ENST00000381280.4:c.234C>T p.Thr78= p.T78= ENST00000381280 NM_022137.5 78 acC/acT 0 +SMOX UCSF GRCh37 20 4155907 4155907 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 102 36 162 0 ENST00000305958.4:c.205C>T p.Leu69Phe p.L69F ENST00000305958 NM_175839.2 69 Ctt/Ttt 0 +SNF8 UCSF GRCh37 17 47010644 47010644 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 125 32 169 0 ENST00000502492.1:c.487G>A p.Val163Met p.V163M ENST00000502492 163 Gtg/Atg 0 +SNIP1 UCSF GRCh37 1 38005897 38005897 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 47 214 0 ENST00000296215.6:c.787C>T p.Pro263Ser p.P263S ENST00000296215 NM_024700.3 263 Cca/Tca 0 +SNRPD2 UCSF GRCh37 19 46191721 46191721 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 45 217 0 ENST00000342669.3:c.106G>A p.Val36Ile p.V36I ENST00000342669 NM_004597.5 36 Gtc/Atc 0 +SNTG1 UCSF GRCh37 8 51362269 51362269 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 16 44 0 ENST00000518864.1:c.261C>T p.Ile87= p.I87= ENST00000518864 87 atC/atT 0 +SNUPN UCSF GRCh37 15 75890747 75890747 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 152 44 193 0 ENST00000308588.5:c.1035G>A p.Lys345= p.K345= ENST00000308588 NM_001042581.1 345 aaG/aaA 0 +SORBS3 UCSF GRCh37 8 22423953 22423953 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 170 19 209 0 ENST00000240123.7:c.1046C>T p.Pro349Leu p.P349L ENST00000240123 NM_005775.4 349 cCc/cTc 0 +SOS2 UCSF GRCh37 14 50585328 50585328 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 81 27 144 0 ENST00000216373.5:c.3733G>A p.Asp1245Asn p.D1245N ENST00000216373 NM_006939.2 1245 Gat/Aat 0 +SPAG11B UCSF GRCh37 8 7320250 7320250 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 173 32 503 0 ENST00000297498.2:c.193C>T p.Pro65Ser p.P65S ENST00000297498 NM_016512.3 65 Ccg/Tcg 0 +SPAG17 UCSF GRCh37 1 118565973 118565973 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 21 111 0 ENST00000336338.5:c.4023G>A p.Gln1341= p.Q1341= ENST00000336338 NM_206996.2 1341 caG/caA 0 +SPAG9 UCSF GRCh37 17 49083481 49083481 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 238 60 306 0 ENST00000262013.7:c.1389G>A p.Glu463= p.E463= ENST00000262013 NM_001130528.2 463 gaG/gaA 0 +SPEN UCSF GRCh37 1 16259115 16259115 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 57 303 0 ENST00000375759.3:c.6380C>T p.Pro2127Leu p.P2127L ENST00000375759 NM_015001.2 2127 cCc/cTc 0 +SPON1 UCSF GRCh37 11 14287095 14287095 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 60 32 148 0 ENST00000310358.7:n.2821C>T *941* ENST00000310358 0 +SPRED2 UCSF GRCh37 2 65571911 65571911 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 35 12 95 0 ENST00000356388.4:c.146C>T p.Pro49Leu p.P49L ENST00000356388 NM_181784.2 49 cCc/cTc 0 +SRRM3 UCSF GRCh37 7 75915110 75915110 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 9 6 16 0 ENST00000326382.8:c.*117C>T *39* ENST00000326382 NM_001110199.1 0 +SRSF4 UCSF GRCh37 1 29475117 29475117 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 341 47 508 0 ENST00000373795.4:c.1290G>A p.Glu430= p.E430= ENST00000373795 NM_005626.4 430 gaG/gaA 0 +SRSF7 UCSF GRCh37 2 38977222 38977222 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 41 188 0 ENST00000313117.6:c.143G>A p.Gly48Glu p.G48E ENST00000313117 NM_001195446.1 48 gGa/gAa 0 +SSC5D UCSF GRCh37 19 56009384 56009384 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 52 13 55 0 ENST00000389623.6:c.1525G>A p.Gly509Ser p.G509S ENST00000389623 NM_001144950.1 509 Ggc/Agc 0 +SSPN UCSF GRCh37 12 26377228 26377228 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 348 65 304 0 ENST00000242729.2:c.282C>T p.Val94= p.V94= ENST00000242729 NM_005086.4 94 gtC/gtT 0 +SSPO UCSF GRCh37 7 149489775 149489775 + non_coding_transcript_exon_variant RNA SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 43 12 100 0 ENST00000378016.2:n.5831G>T *1944* ENST00000378016 0 +STAM UCSF GRCh37 10 17750927 17750927 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 42 160 0 ENST00000377524.3:c.1362G>A p.Gln454= p.Q454= ENST00000377524 NM_003473.3 454 caG/caA 0 +STBD1 UCSF GRCh37 4 77228007 77228007 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 11 6 30 0 ENST00000237642.6:c.85G>A p.Asp29Asn p.D29N ENST00000237642 NM_003943.4 29 Gac/Aac 0 +STK4 UCSF GRCh37 20 43629817 43629817 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 85 19 112 0 ENST00000372806.3:c.970G>A p.Glu324Lys p.E324K ENST00000372806 NM_006282.2 324 Gaa/Aaa 0 +STRA6 UCSF GRCh37 15 74473662 74473662 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 37 6 46 0 ENST00000323940.5:c.1658C>T p.Pro553Leu p.P553L ENST00000323940 NM_001142618.1 553 cCa/cTa 0 +SUFU UCSF GRCh37 10 104309744 104309744 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 133 44 256 0 ENST00000369902.3:c.335G>A p.Gly112Glu p.G112E ENST00000369902 NM_016169.3 112 gGa/gAa 0 +SUMF1 UCSF GRCh37 3 4452646 4452646 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 150 29 175 0 ENST00000272902.5:c.857C>T p.Pro286Leu p.P286L ENST00000272902 NM_182760.3 286 cCc/cTc 0 +SUPV3L1 UCSF GRCh37 10 70949130 70949130 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 14 143 0 ENST00000359655.4:c.680G>A p.Gly227Glu p.G227E ENST00000359655 NM_003171.3 227 gGa/gAa 0 +SVEP1 UCSF GRCh37 9 113151837 113151837 + missense_variant Missense_Mutation SNP T T C 1000g2011may_all_0.0014 P21_Rec Untested WXS Illumina HiSeq 133 107 239 0 ENST00000374469.1:c.9784A>G p.Arg3262Gly p.R3262G ENST00000374469 3262 Aga/Gga 0 +SVIL UCSF GRCh37 10 29822130 29822130 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 30 189 0 ENST00000355867.4:c.1166C>T p.Ser389Phe p.S389F ENST00000355867 NM_021738.2 389 tCt/tTt 0 +SYCE1 UCSF GRCh37 10 135369192 135369192 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 21 17 74 0 ENST00000343131.5:c.739C>T p.His247Tyr p.H247Y ENST00000343131 NM_001143764.1 247 Cac/Tac 0 +SYMPK UCSF GRCh37 19 46352083 46352083 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 108 66 179 0 ENST00000245934.7:c.351C>T p.Leu117= p.L117= ENST00000245934 NM_004819.2 117 ctC/ctT 0 +SYNJ1 UCSF GRCh37 21 34067381 34067381 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 272 35 211 0 ENST00000433931.2:c.808G>A p.Val270Ile p.V270I ENST00000433931 NM_003895.3 270 Gta/Ata 0 +SYNPO UCSF GRCh37 5 150028638 150028638 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 16 92 0 ENST00000394243.1:c.1533G>A p.Glu511= p.E511= ENST00000394243 NM_001166208.1 511 gaG/gaA 0 +TAF1 UCSF GRCh37 X 70618489 70618489 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 38 21 78 0 ENST00000373790.4:c.3685G>A p.Glu1229Lys p.E1229K ENST00000373790 NM_004606.3 1229 Gag/Aag 0 +TAF1L UCSF GRCh37 9 32633675 32633675 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 200 54 240 0 ENST00000242310.4:c.1903C>T p.His635Tyr p.H635Y ENST00000242310 NM_153809.2 635 Cat/Tat 0 +TAP1 UCSF GRCh37 6 32816791 32816791 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 43 8 30 0 ENST00000354258.4:c.1533G>A p.Gln511= p.Q511= ENST00000354258 NM_000593.5 511 caG/caA 0 +TARBP1 UCSF GRCh37 1 234534285 234534285 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 66 18 75 0 ENST00000040877.1:c.4086C>T p.Ile1362= p.I1362= ENST00000040877 NM_005646.3 1362 atC/atT 0 +TAS2R30 UCSF GRCh37 12 11286352 11286352 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 525 110 535 0 ENST00000539585.1:c.492G>A p.Trp164Ter p.W164* ENST00000539585 NM_001097643.1 164 tgG/tgA 0 +TBC1D10A UCSF GRCh37 22 30722783 30722783 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 27 10 36 0 ENST00000215790.7:c.88C>T p.Pro30Ser p.P30S ENST00000215790 NM_031937.2 30 Ccc/Tcc 0 +TBCB UCSF GRCh37 19 36611642 36611642 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 53 11 68 0 ENST00000221855.3:c.289G>C p.Glu97Gln p.E97Q ENST00000221855 NM_001281.2 97 Gag/Cag 0 +TBP UCSF GRCh37 6 170876034 170876034 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 18 9 68 0 ENST00000230354.6:c.614G>A p.Arg205Lys p.R205K ENST00000230354 205 aGa/aAa 0 +TBX10 UCSF GRCh37 11 67399796 67399796 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 100 27 136 0 ENST00000335385.3:c.861G>A p.Arg287= p.R287= ENST00000335385 NM_005995.4 287 agG/agA 0 +TCEB3 UCSF GRCh37 1 24078002 24078002 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.00094 P21_Rec Untested WXS Illumina HiSeq 137 34 206 0 ENST00000418390.2:c.985G>A p.Asp329Asn p.D329N ENST00000418390 NM_003198.2 329 Gac/Aac 0 +TCOF1 UCSF GRCh37 5 149756077 149756077 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 24 8 52 0 ENST00000377797.3:c.2234G>A p.Gly745Glu p.G745E ENST00000377797 NM_001135243.1 745 gGg/gAg 0 +TDP1 UCSF GRCh37 14 90458304 90458304 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 52 14 89 0 ENST00000335725.4:c.1410G>A p.Gln470= p.Q470= ENST00000335725 NM_018319.3 470 caG/caA 0 +TDRD1 UCSF GRCh37 10 115986970 115986970 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 79 28 185 0 ENST00000251864.2:c.3315G>A p.Glu1105= p.E1105= ENST00000251864 NM_198795.1 1105 gaG/gaA 0 +TET1 UCSF GRCh37 10 70427014 70427014 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 45 5 53 0 ENST00000373644.4:c.4673+1G>A p.X1558_splice ENST00000373644 NM_030625.2 0 +TEX2 UCSF GRCh37 17 62290570 62290570 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 37 140 0 ENST00000583097.1:c.1008G>A p.Gly336= p.G336= ENST00000583097 336 ggG/ggA 0 +TFEB UCSF GRCh37 6 41658886 41658886 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 26 6 17 0 ENST00000230323.4:c.66G>A p.Arg22= p.R22= ENST00000230323 NM_007162.2 22 cgG/cgA 0 +TFG UCSF GRCh37 3 100438827 100438827 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 59 13 80 0 ENST00000240851.4:c.193C>T p.Leu65Phe p.L65F ENST00000240851 NM_001195478.1 65 Ctt/Ttt 0 +THAP6 UCSF GRCh37 4 76442089 76442089 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 38 38 121 0 ENST00000311638.3:c.188C>T p.Ser63Leu p.S63L ENST00000311638 NM_144721.4 63 tCg/tTg 0 +THBS1 UCSF GRCh37 15 39882761 39882761 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 26 107 0 ENST00000260356.5:c.2190C>T p.Asp730= p.D730= ENST00000260356 NM_003246.2 730 gaC/gaT 0 +THRA UCSF GRCh37 17 38242972 38242972 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 25 117 0 ENST00000264637.4:c.589G>A p.Gly197Ser p.G197S ENST00000264637 NM_003250.5 197 Ggc/Agc 0 +THSD4 UCSF GRCh37 15 72030269 72030269 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 132 27 229 0 ENST00000355327.3:c.1829C>T p.Pro610Leu p.P610L ENST00000355327 610 cCg/cTg 0 +THSD7A UCSF GRCh37 7 11632897 11632897 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 236 51 411 0 ENST00000423059.4:c.1255G>A p.Val419Ile p.V419I ENST00000423059 NM_015204.2 419 Gtt/Att 0 +THSD7A UCSF GRCh37 7 11632919 11632919 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 237 36 422 0 ENST00000423059.4:c.1233C>T p.Pro411= p.P411= ENST00000423059 NM_015204.2 411 ccC/ccT 0 +THUMPD2 UCSF GRCh37 2 39982434 39982434 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 38 21 57 0 ENST00000505747.1:c.1078+1G>A p.X360_splice ENST00000505747 NM_025264.4 0 +TIGD3 UCSF GRCh37 11 65124305 65124305 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 99 22 129 0 ENST00000309880.5:c.1026C>A p.His342Gln p.H342Q ENST00000309880 NM_145719.2 342 caC/caA 0 +TIMP3 UCSF GRCh37 22 33253331 33253331 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 17 163 0 ENST00000266085.6:c.300C>T p.Tyr100= p.Y100= ENST00000266085 NM_000362.4 100 taC/taT 0 +TLE2 UCSF GRCh37 19 3011090 3011090 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 13 6 34 0 ENST00000262953.6:c.942C>T p.Thr314= p.T314= ENST00000262953 NM_003260.4 314 acC/acT 0 +TLR9 UCSF GRCh37 3 52255337 52255337 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 116 26 172 0 ENST00000360658.2:c.2995C>T p.Pro999Ser p.P999S ENST00000360658 NM_017442.3 999 Ccc/Tcc 0 +TMBIM6 UCSF GRCh37 12 50146858 50146858 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 61 25 144 0 ENST00000267115.5:c.159C>T p.Phe53= p.F53= ENST00000267115 NM_003217.2 53 ttC/ttT 0 +TMC3 UCSF GRCh37 15 81627309 81627309 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 162 42 253 0 ENST00000359440.5:c.2211C>T p.Ile737= p.I737= ENST00000359440 NM_001080532.1 737 atC/atT 0 +TMC6 UCSF GRCh37 17 76122611 76122611 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 37 11 66 0 ENST00000322914.3:c.175G>A p.Val59Met p.V59M ENST00000322914 NM_007267.6 59 Gtg/Atg 0 +TMCO4 UCSF GRCh37 1 20066374 20066374 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 81 35 119 0 ENST00000294543.6:c.1122C>T p.Leu374= p.L374= ENST00000294543 NM_181719.4 374 ctC/ctT 0 +TMEM106B UCSF GRCh37 7 12258127 12258127 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 14 43 0 ENST00000396667.3:c.261G>A p.Gln87= p.Q87= ENST00000396667 NM_018374.3 87 caG/caA 0 +TMEM237 UCSF GRCh37 2 202503751 202503751 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 72 18 116 0 ENST00000409883.2:c.97C>T p.Arg33Cys p.R33C ENST00000409883 NM_001044385.2 33 Cgt/Tgt 0 +TMEM74 UCSF GRCh37 8 109796670 109796670 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 123 19 122 0 ENST00000297459.3:c.658G>A p.Glu220Lys p.E220K ENST00000297459 NM_153015.1 220 Gag/Aag 0 +TMPRSS15 UCSF GRCh37 21 19685352 19685352 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 163 32 163 0 ENST00000284885.3:c.2075G>A p.Arg692Gln p.R692Q ENST00000284885 NM_002772.2 692 cGg/cAg 0 +TMPRSS15 UCSF GRCh37 21 19687538 19687538 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 108 26 117 0 ENST00000284885.3:c.1957G>A p.Gly653Arg p.G653R ENST00000284885 NM_002772.2 653 Gga/Aga 0 +TMTC2 UCSF GRCh37 12 83290098 83290098 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 240 77 402 0 ENST00000321196.3:c.1156C>T p.Gln386Ter p.Q386* ENST00000321196 NM_152588.1 386 Cag/Tag 0 +TMTC4 UCSF GRCh37 13 101288914 101288914 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 56 29 230 0 ENST00000376234.3:c.1017G>A p.Trp339Ter p.W339* ENST00000376234 NM_001079669.1 339 tgG/tgA 0 +TNFRSF10A UCSF GRCh37 8 23082424 23082424 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 19 5 23 0 ENST00000221132.3:c.151G>A p.Gly51Ser p.G51S ENST00000221132 NM_003844.3 51 Ggc/Agc 0 +TNFRSF1A UCSF GRCh37 12 6439070 6439070 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 8 21 0 ENST00000162749.2:c.931C>T p.Arg311Cys p.R311C ENST00000162749 NM_001065.3 311 Cgc/Tgc 0 +TNFRSF8 UCSF GRCh37 1 12198444 12198444 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 4 58 0 ENST00000263932.2:c.1494G>A p.Arg498= p.R498= ENST00000263932 NM_001243.3 498 agG/agA 0 +TNKS1BP1 UCSF GRCh37 11 57088121 57088121 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 30 6 43 0 ENST00000358252.3:c.160C>T p.Pro54Ser p.P54S ENST00000358252 NM_033396.2 54 Cct/Tct 0 +TNPO3 UCSF GRCh37 7 128610265 128610265 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 165 68 295 0 ENST00000265388.5:c.2535C>T p.Leu845= p.L845= ENST00000265388 845 ctC/ctT 0 +TNRC6A UCSF GRCh37 16 24826609 24826609 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 67 21 91 0 ENST00000395799.3:c.4814G>A p.Ser1605Asn p.S1605N ENST00000395799 NM_014494.2 1605 aGt/aAt 0 +TNRC6B UCSF GRCh37 22 40681770 40681770 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 339 73 405 0 ENST00000454349.2:c.3704C>T p.Pro1235Leu p.P1235L ENST00000454349 NM_001162501.1 1235 cCc/cTc 0 +TOM1L2 UCSF GRCh37 17 17786035 17786035 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 116 28 153 0 ENST00000379504.3:c.644C>T p.Thr215Ile p.T215I ENST00000379504 NM_001082968.1 215 aCa/aTa 0 +TOPBP1 UCSF GRCh37 3 133331320 133331320 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 164 37 206 0 ENST00000260810.5:c.3948G>A p.Glu1316= p.E1316= ENST00000260810 NM_007027.3 1316 gaG/gaA 0 +TOPBP1 UCSF GRCh37 3 133375522 133375522 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 237 59 234 0 ENST00000260810.5:c.543G>A p.Glu181= p.E181= ENST00000260810 NM_007027.3 181 gaG/gaA 0 +TOR2A UCSF GRCh37 9 130496642 130496642 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 62 19 70 0 ENST00000373284.5:c.353C>T p.Pro118Leu p.P118L ENST00000373284 NM_001085347.2 118 cCc/cTc 0 +TP53 UCSF GRCh37 17 7578388 7578388 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 53 43 127 0 ENST00000269305.4:c.542G>C p.Arg181Pro p.R181P ENST00000269305 NM_001126112.2 181 cGc/cCc 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 58 44 129 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TP53 UCSF GRCh37 17 7579434 7579434 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 152 59 241 0 ENST00000269305.4:c.253C>T p.Pro85Ser p.P85S ENST00000269305 NM_001126112.2 85 Cct/Tct 0 +TPM4 UCSF GRCh37 19 16186900 16186900 + upstream_gene_variant 5'Flank SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 24 3 31 0 ENST00000300933 NM_003290.2 0 +TPO UCSF GRCh37 2 1507752 1507752 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 68 25 136 0 ENST00000329066.4:c.2419C>T p.Pro807Ser p.P807S ENST00000329066 NM_001206744.1 807 Ccc/Tcc 0 +TPTE2 UCSF GRCh37 13 20056662 20056662 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 63 26 189 0 ENST00000400230.2:c.145G>A p.Glu49Lys p.E49K ENST00000400230 49 Gaa/Aaa 0 +TRHDE UCSF GRCh37 12 72771831 72771831 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 73 15 75 0 ENST00000261180.4:c.1110C>T p.Leu370= p.L370= ENST00000261180 NM_013381.2 370 ctC/ctT 0 +TRIM14 UCSF GRCh37 9 100850237 100850237 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 13 4 17 0 ENST00000341469.2:c.844C>T p.Leu282= p.L282= ENST00000341469 NM_014788.2 282 Ctg/Ttg 0 +TRIM28 UCSF GRCh37 19 59059517 59059517 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 316 77 457 0 ENST00000253024.5:c.1071C>T p.Asn357= p.N357= ENST00000253024 NM_005762.2 357 aaC/aaT 0 +TRIM44 UCSF GRCh37 11 35706878 35706878 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 29 23 111 0 ENST00000299413.5:c.741C>T p.Asp247= p.D247= ENST00000299413 NM_017583.4 247 gaC/gaT 0 +TRIOBP UCSF GRCh37 22 38151613 38151613 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 107 30 156 0 ENST00000406386.3:c.5634G>A p.Trp1878Ter p.W1878* ENST00000406386 NM_001039141.2 1878 tgG/tgA 0 +TRMT12 UCSF GRCh37 8 125464397 125464397 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 175 27 153 0 ENST00000328599.3:c.1229T>C p.Val410Ala p.V410A ENST00000328599 NM_017956.3 410 gTg/gCg 0 +TRO UCSF GRCh37 X 54949475 54949475 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 13 70 0 ENST00000173898.7:c.510G>A p.Leu170= p.L170= ENST00000173898 NM_001039705.2 170 ttG/ttA 0 +TRPS1 UCSF GRCh37 8 116426892 116426892 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 315 48 228 0 ENST00000220888.5:c.3205G>A p.Glu1069Lys p.E1069K ENST00000220888 1069 Gaa/Aaa 0 +TSFM UCSF GRCh37 12 58190181 58190181 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 41 10 60 0 ENST00000454289.3:c.793C>T p.Pro265Ser p.P265S ENST00000454289 NM_005726.5 265 Ccc/Tcc 0 +TSHZ3 UCSF GRCh37 19 31768293 31768293 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 157 31 216 0 ENST00000240587.4:c.2406C>T p.Ser802= p.S802= ENST00000240587 NM_020856.2 802 tcC/tcT 0 +TSPAN3 UCSF GRCh37 15 77339196 77339196 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 17 4 35 0 ENST00000267970.4:c.743C>T p.Thr248Ile p.T248I ENST00000267970 NM_001168412.1 248 aCt/aTt 0 +TST UCSF GRCh37 22 37414267 37414267 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 53 13 69 0 ENST00000249042.3:c.507G>A p.Leu169= p.L169= ENST00000249042 NM_003312.5 169 ctG/ctA 0 +TTC17 UCSF GRCh37 11 43469637 43469637 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 40 158 0 ENST00000039989.4:c.2751G>A p.Val917= p.V917= ENST00000039989 NM_018259.5 917 gtG/gtA 0 +TTC21B UCSF GRCh37 2 166756331 166756331 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 23 91 0 ENST00000243344.7:c.2817G>A p.Arg939= p.R939= ENST00000243344 NM_024753.4 939 cgG/cgA 0 +TTC21B UCSF GRCh37 2 166797655 166797655 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 81 25 128 0 ENST00000243344.7:c.592C>T p.Leu198= p.L198= ENST00000243344 NM_024753.4 198 Ctg/Ttg 0 +TTC4 UCSF GRCh37 1 55207137 55207137 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 161 28 216 0 ENST00000371281.3:c.1115C>T p.Pro372Leu p.P372L ENST00000371281 NM_004623.4 372 cCt/cTt 0 +TTK UCSF GRCh37 6 80736183 80736183 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 80 39 229 0 ENST00000369798.2:c.1346C>T p.Ser449Phe p.S449F ENST00000369798 NM_003318.4 449 tCt/tTt 0 +TTN UCSF GRCh37 2 179560080 179560080 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 68 25 127 0 ENST00000591111.1:c.30314C>T p.Pro10105Leu p.P10105L ENST00000591111 10105 cCt/cTt 0 +TTN UCSF GRCh37 2 179427207 179427207 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 223 75 385 0 ENST00000591111.1:c.78729G>A p.Trp26243Ter p.W26243* ENST00000591111 26243 tgG/tgA 0 +TUBAL3 UCSF GRCh37 10 5436278 5436278 + synonymous_variant Silent SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 115 57 142 0 ENST00000380419.3:c.543C>A p.Ala181= p.A181= ENST00000380419 NM_024803.2 181 gcC/gcA 0 +TUFT1 UCSF GRCh37 1 151546806 151546806 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 21 93 0 ENST00000368849.3:c.655G>A p.Glu219Lys p.E219K ENST00000368849 NM_020127.2 219 Gag/Aag 0 +TXNDC12 UCSF GRCh37 1 52489209 52489209 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 107 30 144 0 ENST00000371626.4:c.393G>A p.Glu131= p.E131= ENST00000371626 NM_015913.3 131 gaG/gaA 0 +TXNDC16 UCSF GRCh37 14 52899137 52899137 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 103 28 155 1 ENST00000281741.4:c.2363G>A p.Arg788Lys p.R788K ENST00000281741 NM_020784.2 788 aGa/aAa 0 +TXNDC5 UCSF GRCh37 6 7884664 7884664 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 174 38 213 0 ENST00000379757.4:c.1104C>T p.Phe368= p.F368= ENST00000379757 NM_030810.3 368 ttC/ttT 0 +TYMP UCSF GRCh37 22 50967706 50967706 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 74 18 102 0 ENST00000252029.3:c.276C>T p.Thr92= p.T92= ENST00000252029 NM_001953.4 92 acC/acT 0 +TYW1B UCSF GRCh37 7 72178679 72178679 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 121 41 330 0 ENST00000343721.5:c.148C>T p.Pro50Ser p.P50S ENST00000343721 50 Cca/Tca 0 +TYW5 UCSF GRCh37 2 200798002 200798002 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 29 132 0 ENST00000354611.4:c.736G>A p.Val246Met p.V246M ENST00000354611 NM_001039693.2 246 Gtg/Atg 0 +U2AF2 UCSF GRCh37 19 56171880 56171880 + splice_acceptor_variant Splice_Site SNP A A C NOVEL P21_Rec Untested WXS Illumina HiSeq 18 6 28 1 ENST00000308924.4:c.231-2A>C p.X77_splice ENST00000308924 0 +U2SURP UCSF GRCh37 3 142735817 142735817 + splice_region_variant,synonymous_variant Splice_Region SNP T T A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 26 167 0 ENST00000473835.2:c.570T>A p.Pro190= p.P190= ENST00000473835 NM_001080415.1 190 ccT/ccA 0 +UBE4B UCSF GRCh37 1 10221321 10221321 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 101 27 141 0 ENST00000343090.6:c.3175G>A p.Glu1059Lys p.E1059K ENST00000343090 NM_001105562.2 1059 Gaa/Aaa 0 +UBFD1 UCSF GRCh37 16 23570865 23570865 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 24 134 0 ENST00000395878.3:c.432G>A p.Val144= p.V144= ENST00000395878 NM_019116.2 144 gtG/gtA 0 +UBOX5 UCSF GRCh37 20 3102943 3102943 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 16 133 0 ENST00000217173.2:c.342G>A p.Ala114= p.A114= ENST00000217173 NM_001267584.1 114 gcG/gcA 0 +UGDH UCSF GRCh37 4 39511429 39511429 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.003,1000g2011may_all_0.0022 P21_Rec Untested WXS Illumina HiSeq 92 15 114 1 ENST00000316423.6:c.762G>A p.Ala254= p.A254= ENST00000316423 NM_001184701.1 254 gcG/gcA 0 +UGP2 UCSF GRCh37 2 64109776 64109776 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 99 41 173 1 ENST00000337130.5:c.432G>A p.Gln144= p.Q144= ENST00000337130 NM_006759.3 144 caG/caA 0 +UMODL1 UCSF GRCh37 21 43543178 43543178 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 15 151 0 ENST00000408910.2:c.3065C>T p.Pro1022Leu p.P1022L ENST00000408910 NM_001004416.2 1022 cCc/cTc 0 +UNC13B UCSF GRCh37 9 35385781 35385781 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 151 45 184 0 ENST00000378495.3:c.2689C>T p.Leu897= p.L897= ENST00000378495 NM_006377.3 897 Ctg/Ttg 0 +UNC79 UCSF GRCh37 14 94063753 94063753 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 135 29 241 0 ENST00000393151.2:c.3239C>T p.Thr1080Ile p.T1080I ENST00000393151 1080 aCc/aTc 0 +UNC80 UCSF GRCh37 2 210840926 210840926 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 30 21 92 0 ENST00000439458.1:c.8473C>T p.Leu2825= p.L2825= ENST00000439458 NM_032504.1 2825 Ctg/Ttg 0 +UNKL UCSF GRCh37 16 1416349 1416349 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 10 5 29 0 ENST00000389221.4:c.1935G>A p.Arg645= p.R645= ENST00000389221 NM_001193388.3 645 cgG/cgA 0 +URM1 UCSF GRCh37 9 131140376 131140376 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 305 87 432 0 ENST00000372853.4:c.97G>A p.Glu33Lys p.E33K ENST00000372853 NM_001265582.1 33 Gag/Aag 0 +UROC1 UCSF GRCh37 3 126211359 126211359 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 39 6 60 0 ENST00000290868.2:c.1510G>A p.Val504Met p.V504M ENST00000290868 NM_144639.2 504 Gtg/Atg 0 +USP15 UCSF GRCh37 12 62688014 62688014 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 16 87 0 ENST00000280377.5:c.144C>T p.Asp48= p.D48= ENST00000280377 NM_001252078.1 48 gaC/gaT 0 +USP24 UCSF GRCh37 1 55591349 55591349 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 112 36 179 0 ENST00000294383.6:c.3718C>T p.Leu1240= p.L1240= ENST00000294383 NM_015306.2 1240 Cta/Tta 0 +USP4 UCSF GRCh37 3 49316274 49316274 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 228 59 342 1 ENST00000265560.4:c.2706G>A p.Val902= p.V902= ENST00000265560 NM_003363.3 902 gtG/gtA 0 +VARS UCSF GRCh37 6 31759704 31759704 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 53 6 49 0 ENST00000375663.3:c.916G>A p.Glu306Lys p.E306K ENST00000375663 NM_006295.2 306 Gag/Aag 0 +VARS UCSF GRCh37 6 31747218 31747218 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 74 9 39 0 ENST00000375663.3:c.3384C>T p.Thr1128= p.T1128= ENST00000375663 NM_006295.2 1128 acC/acT 0 +VPRBP UCSF GRCh37 3 51440745 51440745 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 294 90 442 0 ENST00000423656.1:c.3010C>T p.Leu1004= p.L1004= ENST00000423656 1004 Ctg/Ttg 0 +VPS13C UCSF GRCh37 15 62202505 62202505 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 44 8 57 0 ENST00000261517.5:c.8716-1G>A p.X2906_splice ENST00000261517 NM_020821.2 0 +VPS37C UCSF GRCh37 11 60900006 60900006 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 40 14 76 0 ENST00000301765.5:c.354G>A p.Met118Ile p.M118I ENST00000301765 NM_017966.4 118 atG/atA 0 +VPS41 UCSF GRCh37 7 38835080 38835080 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 87 28 196 0 ENST00000310301.4:c.702G>A p.Trp234Ter p.W234* ENST00000310301 NM_014396.3 234 tgG/tgA 0 +VWC2 UCSF GRCh37 7 49951759 49951759 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 66 11 130 0 ENST00000340652.4:c.956G>A p.Arg319Lys p.R319K ENST00000340652 NM_198570.3 319 aGa/aAa 0 +WAPAL UCSF GRCh37 10 88259980 88259980 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 200 66 406 0 ENST00000298767.5:c.1020G>A p.Gly340= p.G340= ENST00000298767 NM_015045.2 340 ggG/ggA 0 +WBP2NL UCSF GRCh37 22 42418293 42418293 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 34 150 0 ENST00000328823.9:c.447C>T p.Phe149= p.F149= ENST00000328823 NM_152613.2 149 ttC/ttT 0 +WDHD1 UCSF GRCh37 14 55408278 55408278 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 68 21 85 0 ENST00000360586.3:c.3320C>T p.Ser1107Phe p.S1107F ENST00000360586 NM_007086.3 1107 tCt/tTt 0 +WDR19 UCSF GRCh37 4 39206875 39206875 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 228 45 204 0 ENST00000399820.3:c.705C>T p.Val235= p.V235= ENST00000399820 NM_025132.3 235 gtC/gtT 0 +WDR33 UCSF GRCh37 2 128463960 128463960 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 161 55 310 0 ENST00000322313.4:c.3948G>A p.Gly1316= p.G1316= ENST00000322313 NM_018383.4 1316 ggG/ggA 0 +WDR34 UCSF GRCh37 9 131403107 131403107 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 79 22 124 0 ENST00000372715.2:c.298C>T p.Pro100Ser p.P100S ENST00000372715 NM_052844.3 100 Ccg/Tcg 0 +WDR35 UCSF GRCh37 2 20166556 20166556 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 61 22 118 0 ENST00000345530.3:c.1123G>A p.Gly375Ser p.G375S ENST00000345530 NM_001006657.1 375 Ggt/Agt 0 +WDR36 UCSF GRCh37 5 110445982 110445982 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 218 48 229 0 ENST00000506538.2:c.1589G>A p.Gly530Glu p.G530E ENST00000506538 NM_139281.2 530 gGa/gAa 0 +WDR60 UCSF GRCh37 7 158718922 158718922 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 123 42 235 0 ENST00000407559.3:c.2302G>A p.Val768Ile p.V768I ENST00000407559 NM_018051.4 768 Gta/Ata 0 +WDR7 UCSF GRCh37 18 54363620 54363620 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 102 25 187 0 ENST00000254442.3:c.1505G>A p.Gly502Glu p.G502E ENST00000254442 NM_015285.2 502 gGa/gAa 0 +WDR7 UCSF GRCh37 18 54385293 54385293 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 91 28 160 0 ENST00000254442.3:c.1677C>T p.His559= p.H559= ENST00000254442 NM_015285.2 559 caC/caT 0 +WNK2 UCSF GRCh37 9 96010058 96010058 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 14 6 26 0 ENST00000297954.4:c.1776G>A p.Pro592= p.P592= ENST00000297954 NM_001282394.1 592 ccG/ccA 0 +WNK2 UCSF GRCh37 9 96051290 96051290 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 28 7 40 0 ENST00000297954.4:c.4365G>A p.Gly1455= p.G1455= ENST00000297954 NM_001282394.1 1455 ggG/ggA 0 +WT1 UCSF GRCh37 11 32456391 32456391 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 13 4 26 0 ENST00000332351.3:c.501G>A p.Gln167= p.Q167= ENST00000332351 NM_024426.4 167 caG/caA 0 +XAB2 UCSF GRCh37 19 7687515 7687515 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 70 21 113 0 ENST00000358368.4:c.1404G>A p.Glu468= p.E468= ENST00000358368 NM_020196.2 468 gaG/gaA 0 +XAB2 UCSF GRCh37 19 7692635 7692635 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 159 31 186 0 ENST00000358368.4:c.303G>A p.Arg101= p.R101= ENST00000358368 NM_020196.2 101 agG/agA 0 +XIRP2 UCSF GRCh37 2 168106609 168106609 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 105 44 179 0 ENST00000409195.1:c.8707G>A p.Gly2903Ser p.G2903S ENST00000409195 NM_152381.5 2903 Ggc/Agc 0 +XKR6 UCSF GRCh37 8 11058163 11058163 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 17 9 51 0 ENST00000416569.2:c.686G>A p.Gly229Glu p.G229E ENST00000416569 NM_173683.3 229 gGg/gAg 0 +YAF2 UCSF GRCh37 12 42555550 42555550 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 49 6 98 0 ENST00000534854.2:c.170C>T p.Ser57Phe p.S57F ENST00000534854 NM_005748.4 57 tCc/tTc 0 +YLPM1 UCSF GRCh37 14 75295966 75295966 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 252 53 423 0 ENST00000325680.7:c.6214G>A p.Ala2072Thr p.A2072T ENST00000325680 NM_019589.2 2072 Gcc/Acc 0 +YWHAZ UCSF GRCh37 8 101932975 101932975 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 15 112 0 ENST00000353245.3:c.684G>A p.Trp228Ter p.W228* ENST00000353245 NM_003406.3 228 tgG/tgA 0 +ZACN UCSF GRCh37 17 74078655 74078655 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 105 20 136 0 ENST00000334586.5:c.1160G>A p.Gly387Glu p.G387E ENST00000334586 NM_180990.3 387 gGa/gAa 0 +ZBTB9 UCSF GRCh37 6 33423368 33423368 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 290 38 212 0 ENST00000395064.2:c.491C>T p.Ser164Phe p.S164F ENST00000395064 NM_152735.3 164 tCc/tTc 0 +ZEB1 UCSF GRCh37 10 31784732 31784732 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 273 46 279 0 ENST00000320985.10:c.284G>A p.Gly95Glu p.G95E ENST00000320985 95 gGg/gAg 0 +ZFHX3 UCSF GRCh37 16 72821920 72821920 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 68 27 111 0 ENST00000268489.5:c.10255C>T p.Pro3419Ser p.P3419S ENST00000268489 NM_006885.3 3419 Ccc/Tcc 0 +ZFHX4 UCSF GRCh37 8 77766808 77766808 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 250 87 398 0 ENST00000521891.2:c.7651C>T p.Leu2551= p.L2551= ENST00000521891 NM_024721.4 2551 Ctg/Ttg 0 +ZFPM2 UCSF GRCh37 8 106813523 106813523 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 517 58 505 0 ENST00000407775.2:c.1213G>A p.Glu405Lys p.E405K ENST00000407775 NM_012082.3 405 Gaa/Aaa 0 +ZFPM2 UCSF GRCh37 8 106813752 106813752 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 443 84 453 0 ENST00000407775.2:c.1442C>T p.Ser481Leu p.S481L ENST00000407775 NM_012082.3 481 tCa/tTa 0 +ZFYVE26 UCSF GRCh37 14 68282603 68282603 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 105 21 176 0 ENST00000347230.4:c.78G>A p.Arg26= p.R26= ENST00000347230 NM_015346.3 26 agG/agA 0 +ZFYVE9 UCSF GRCh37 1 52811748 52811748 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 36 184 0 ENST00000287727.3:c.4133G>A p.Gly1378Glu p.G1378E ENST00000287727 NM_004799.3 1378 gGg/gAg 0 +ZHX2 UCSF GRCh37 8 123964106 123964106 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 252 45 236 1 ENST00000314393.4:c.356C>T p.Thr119Ile p.T119I ENST00000314393 NM_014943.3 119 aCc/aTc 0 +ZHX3 UCSF GRCh37 20 39833299 39833299 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 188 39 202 0 ENST00000309060.3:c.258C>T p.Ser86= p.S86= ENST00000309060 86 tcC/tcT 0 +ZNF107 UCSF GRCh37 7 64168031 64168031 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 102 16 103 0 ENST00000344930.3:c.1349G>A p.Ser450Asn p.S450N ENST00000344930 NM_001013746.1 450 aGc/aAc 0 +ZNF155 UCSF GRCh37 19 44501158 44501158 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 346 95 441 1 ENST00000270014.2:c.1149G>A p.Trp383Ter p.W383* ENST00000270014 NM_198089.2 383 tgG/tgA 0 +ZNF167 UCSF GRCh37 3 44612356 44612356 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 202 77 332 0 ENST00000273320.3:c.1754G>A p.Gly585Glu p.G585E ENST00000273320 NM_018651.2 585 gGg/gAg 0 +ZNF211 UCSF GRCh37 19 58152509 58152509 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 201 48 289 0 ENST00000347302.3:c.655G>A p.Ala219Thr p.A219T ENST00000347302 NM_198855.2 219 Gcg/Acg 0 +ZNF217 UCSF GRCh37 20 52192575 52192575 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 118 31 140 0 ENST00000302342.3:c.2728G>A p.Ala910Thr p.A910T ENST00000302342 NM_006526.2 910 Gca/Aca 0 +ZNF225 UCSF GRCh37 19 44635006 44635006 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 187 145 345 0 ENST00000262894.6:c.239G>A p.Gly80Asp p.G80D ENST00000262894 NM_013362.2 80 gGc/gAc 0 +ZNF248 UCSF GRCh37 10 38120932 38120932 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 338 65 277 1 ENST00000357328.4:c.1351C>T p.Leu451Phe p.L451F ENST00000357328 NM_001267597.1 451 Ctc/Ttc 0 +ZNF267 UCSF GRCh37 16 31925937 31925937 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 138 21 168 0 ENST00000300870.10:c.367G>A p.Glu123Lys p.E123K ENST00000300870 NM_003414.5 123 Gaa/Aaa 0 +ZNF292 UCSF GRCh37 6 87964427 87964427 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 139 81 346 0 ENST00000369577.3:c.1080G>A p.Glu360= p.E360= ENST00000369577 NM_015021.1 360 gaG/gaA 0 +ZNF331 UCSF GRCh37 19 54080807 54080807 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 19 207 0 ENST00000253144.9:c.993G>A p.Glu331= p.E331= ENST00000253144 NM_018555.5 331 gaG/gaA 0 +ZNF34 UCSF GRCh37 8 145999772 145999772 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 100 56 229 0 ENST00000343459.4:c.562C>T p.Pro188Ser p.P188S ENST00000343459 188 Cct/Tct 0 +ZNF410 UCSF GRCh37 14 74360506 74360506 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 90 36 167 0 ENST00000555044.1:c.40G>A p.Val14Ile p.V14I ENST00000555044 NM_021188.2 14 Gta/Ata 0 +ZNF434 UCSF GRCh37 16 3433513 3433513 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 84 27 149 0 ENST00000396846.3:c.1433C>T p.Ser478Phe p.S478F ENST00000396846 478 tCc/tTc 0 +ZNF444 UCSF GRCh37 19 56658566 56658566 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 10 7 28 0 ENST00000337080.3:c.286G>A p.Glu96Lys p.E96K ENST00000337080 NM_018337.3 96 Gag/Aag 0 +ZNF446 UCSF GRCh37 19 58989194 58989194 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 23 8 36 0 ENST00000594369.1:c.532+1G>A p.X178_splice ENST00000594369 NM_017908.2 0 +ZNF451 UCSF GRCh37 6 57017100 57017100 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 204 32 165 0 ENST00000370706.4:c.2834C>T p.Pro945Leu p.P945L ENST00000370706 NM_001031623.2 945 cCt/cTt 0 +ZNF454 UCSF GRCh37 5 178373410 178373410 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 105 15 203 0 ENST00000320129.3:c.84G>A p.Trp28Ter p.W28* ENST00000320129 NM_182594.2 28 tgG/tgA 0 +ZNF484 UCSF GRCh37 9 95610124 95610124 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 144 33 150 0 ENST00000375495.3:c.945G>A p.Lys315= p.K315= ENST00000375495 NM_031486.2 315 aaG/aaA 0 +ZNF497 UCSF GRCh37 19 58868933 58868933 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 19 8 36 0 ENST00000311044.3:c.69G>A p.Lys23= p.K23= ENST00000311044 NM_198458.2 23 aaG/aaA 0 +ZNF502 UCSF GRCh37 3 44762784 44762784 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 179 50 243 0 ENST00000296091.4:c.475G>A p.Glu159Lys p.E159K ENST00000296091 NM_001134440.1 159 Gaa/Aaa 0 +ZNF518B UCSF GRCh37 4 10445645 10445645 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 175 55 252 0 ENST00000326756.3:c.2308G>A p.Val770Met p.V770M ENST00000326756 NM_053042.2 770 Gtg/Atg 0 +ZNF546 UCSF GRCh37 19 40520077 40520077 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 194 64 233 0 ENST00000347077.4:c.900C>T p.Pro300= p.P300= ENST00000347077 NM_178544.3 300 ccC/ccT 0 +ZNF551 UCSF GRCh37 19 58196644 58196644 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 367 53 395 0 ENST00000282296.5:c.96G>A p.Glu32= p.E32= ENST00000282296 32 gaG/gaA 0 +ZNF564 UCSF GRCh37 19 12638717 12638717 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 52 161 0 ENST00000339282.7:c.205G>A p.Glu69Lys p.E69K ENST00000339282 NM_144976.3 69 Gag/Aag 0 +ZNF595 UCSF GRCh37 4 86793 86793 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 168 46 212 0 ENST00000380882.5:n.1171C>T *391* ENST00000380882 0 +ZNF614 UCSF GRCh37 19 52520123 52520123 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 101 87 160 0 ENST00000270649.6:c.728G>A p.Ser243Asn p.S243N ENST00000270649 NM_025040.3 243 aGt/aAt 0 +ZNF627 UCSF GRCh37 19 11725386 11725386 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 349 89 408 0 ENST00000361113.5:c.48G>A p.Glu16= p.E16= ENST00000361113 NM_145295.3 16 gaG/gaA 0 +ZNF653 UCSF GRCh37 19 11596546 11596546 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 228 45 294 0 ENST00000293771.5:c.1495G>A p.Val499Met p.V499M ENST00000293771 NM_138783.3 499 Gtg/Atg 0 +ZNF660 UCSF GRCh37 3 44636524 44636524 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 30 121 0 ENST00000322734.2:c.839G>A p.Gly280Glu p.G280E ENST00000322734 NM_173658.2 280 gGg/gAg 0 +ZNF689 UCSF GRCh37 16 30616479 30616479 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 28 176 0 ENST00000287461.3:c.609C>T p.Cys203= p.C203= ENST00000287461 NM_138447.2 203 tgC/tgT 0 +ZNF701 UCSF GRCh37 19 53077350 53077350 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 250 50 294 0 ENST00000301093.2:c.148G>A p.Val50Ile p.V50I ENST00000301093 50 Gta/Ata 0 +ZNF716 UCSF GRCh37 7 57510025 57510025 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 108 81 209 0 ENST00000420713.1:c.31C>T p.Arg11Ter p.R11* ENST00000420713 NM_001159279.1 11 Cga/Tga 0 +ZNF808 UCSF GRCh37 19 53058370 53058370 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 493 346 906 1 ENST00000359798.4:c.2201C>T p.Pro734Leu p.P734L ENST00000359798 NM_001039886.3 734 cCt/cTt 0 +ZNF93 UCSF GRCh37 19 20044216 20044216 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 116 33 103 0 ENST00000343769.5:c.452G>A p.Gly151Glu p.G151E ENST00000343769 NM_031218.3 151 gGg/gAg 0 +ZP3 UCSF GRCh37 7 76069815 76069815 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 211 43 345 0 ENST00000394857.3:c.947C>T p.Ala316Val p.A316V ENST00000394857 NM_001110354.1 316 gCt/gTt 0 +ZSCAN2 UCSF GRCh37 15 85164467 85164467 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 187 51 289 0 ENST00000448803.2:c.1041C>T p.Ser347= p.S347= ENST00000448803 NM_181877.3 347 tcC/tcT 0 +ZSCAN2 UCSF GRCh37 15 85165136 85165136 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 207 57 256 0 ENST00000448803.2:c.1710C>T p.Asn570= p.N570= ENST00000448803 NM_181877.3 570 aaC/aaT 0 +ZSWIM5 UCSF GRCh37 1 45525839 45525839 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 94 15 119 0 ENST00000359600.5:c.1033G>A p.Val345Met p.V345M ENST00000359600 NM_020883.1 345 Gtg/Atg 0 +ACVRL1 UCSF GRCh37 12 52309821 52309821 + splice_region_variant,synonymous_variant Splice_Region SNP C C A NOVEL P24_Pri Untested WXS Illumina HiSeq 99 22 89 1 ENST00000388922.4:c.1050C>A p.Gly350= p.G350= ENST00000388922 NM_000020.2 350 ggC/ggA 0 +ASPM UCSF GRCh37 1 197071895 197071895 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Pri Untested WXS Illumina HiSeq 202 119 445 0 ENST00000367409.4:c.6486G>C p.Lys2162Asn p.K2162N ENST00000367409 NM_018136.4 2162 aaG/aaC 0 +ATRX UCSF GRCh37 X 76939340 76939343 + frameshift_variant Frame_Shift_Del DEL CTAC CTAC - NOVEL P24_Pri Untested WXS Illumina HiSeq 53 0 ENST00000373344.5:c.1405_1408delGTAG p.Val469IlefsTer44 p.V469Ifs*44 ENST00000373344 NM_000489.3 469 GTAGat/at 0 +ATRX UCSF GRCh37 X 76920171 76920172 + frameshift_variant Frame_Shift_Del DEL TC TC - NOVEL P24_Pri Untested WXS Illumina HiSeq 15 0 ENST00000373344.5:c.3905_3906del p.Arg1302AsnfsTer6 p.R1302Nfs*6 ENST00000373344 NM_000489.3 1302 aGA/a 0 +CNTN6 UCSF GRCh37 3 1262473 1262473 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Pri Untested WXS Illumina HiSeq 93 11 144 0 ENST00000350110.2:c.158A>G p.Asn53Ser p.N53S ENST00000350110 NM_014461.2 53 aAt/aGt 0 +CYP4A22 UCSF GRCh37 1 47606476 47606476 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Pri Untested WXS Illumina HiSeq 179 39 258 0 ENST00000371891.3:c.220C>T p.Arg74Trp p.R74W ENST00000371891 NM_001010969.2 74 Cgg/Tgg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Pri Untested WXS Illumina HiSeq 16 3 28 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +MARK4 UCSF GRCh37 19 45769492 45769492 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Pri Untested WXS Illumina HiSeq 130 53 207 0 ENST00000262891.4:c.502G>T p.Ala168Ser p.A168S ENST00000262891 NM_001199867.1 168 Gct/Tct 0 +MTUS1 UCSF GRCh37 8 17504501 17504501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Pri Untested WXS Illumina HiSeq 162 48 269 0 ENST00000262102.6:c.3589G>A p.Ala1197Thr p.A1197T ENST00000262102 NM_001001924.2 1197 Gca/Aca 0 +TMEM55B UCSF GRCh37 14 20927400 20927400 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Pri Untested WXS Illumina HiSeq 35 18 71 0 ENST00000250489.4:c.655G>C p.Gly219Arg p.G219R ENST00000250489 219 Ggc/Cgc 0 +TP53 UCSF GRCh37 17 7576858 7576858 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P24_Pri Untested WXS Illumina HiSeq 117 0 ENST00000269305.4:c.988delC p.Leu330PhefsTer15 p.L330Ffs*15 ENST00000269305 NM_001126112.2 330 Ctt/tt 0 +UNC5C UCSF GRCh37 4 96123949 96123949 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Pri Untested WXS Illumina HiSeq 52 16 57 0 ENST00000453304.1:c.2069T>A p.Leu690Gln p.L690Q ENST00000453304 NM_003728.3 690 cTg/cAg 0 +VGLL1 UCSF GRCh37 X 135630884 135630884 + synonymous_variant Silent SNP G G A NOVEL P24_Pri Untested WXS Illumina HiSeq 168 19 207 0 ENST00000370634.3:c.351G>A p.Pro117= p.P117= ENST00000370634 NM_016267.3 117 ccG/ccA 0 +ABHD11 UCSF GRCh37 7 73153014 73153014 + synonymous_variant Silent SNP G G T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 150 20 148 0 ENST00000222800.3:c.114C>A p.Pro38= p.P38= ENST00000222800 NM_148912.2 38 ccC/ccA 0 +AKAP3 UCSF GRCh37 12 4736308 4736308 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec1 Untested WXS Illumina HiSeq 238 36 211 1 ENST00000228850.1:c.1760A>G p.Lys587Arg p.K587R ENST00000228850 587 aAg/aGg 0 +ASB2 UCSF GRCh37 14 94423111 94423111 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 27 5 24 0 ENST00000315988.4:c.167+1G>A p.X56_splice ENST00000315988 NM_016150.4 0 +ASPM UCSF GRCh37 1 197071895 197071895 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec1 Untested WXS Illumina HiSeq 398 48 445 0 ENST00000367409.4:c.6486G>C p.Lys2162Asn p.K2162N ENST00000367409 NM_018136.4 2162 aaG/aaC 0 +ATRX UCSF GRCh37 X 76939340 76939343 + frameshift_variant Frame_Shift_Del DEL CTAC CTAC - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 30 0 ENST00000373344.5:c.1405_1408delGTAG p.Val469IlefsTer44 p.V469Ifs*44 ENST00000373344 NM_000489.3 469 GTAGat/at 0 +BBS7 UCSF GRCh37 4 122754493 122754493 + missense_variant Missense_Mutation SNP C C A NOVEL P24_Rec1 Untested WXS Illumina HiSeq 80 12 108 0 ENST00000264499.4:c.1569G>T p.Trp523Cys p.W523C ENST00000264499 NM_176824.2 523 tgG/tgT 0 +C4A UCSF GRCh37 6 31996966 31996966 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.041,1000g2011may_all_0.0752,snp132_rs17855807 P24_Rec1 Untested WXS Illumina HiSeq 30 5 41 0 ENST00000435363.2:c.3527G>A p.Ser1176Asn p.S1176N ENST00000435363 NM_001002029.3 1176 aGc/aAc 0 +DROSHA UCSF GRCh37 5 31435970 31435970 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 69 11 67 0 ENST00000344624.3:c.2944G>A p.Val982Ile p.V982I ENST00000344624 982 Gtc/Atc 0 +GLCE UCSF GRCh37 15 69560951 69560951 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 11 0 ENST00000261858.2:c.1222del p.Ala408LeufsTer5 p.A408Lfs*5 ENST00000261858 NM_015554.1 408 Gct/ct 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 27 4 28 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KRT6B UCSF GRCh37 12 52843581 52843581 + synonymous_variant Silent SNP A A G snp132_rs3194297 P24_Rec1 Untested WXS Illumina HiSeq 10 5 12 0 ENST00000252252.3:c.873T>C p.Leu291= p.L291= ENST00000252252 NM_005555.3 291 ctT/ctC 0 +MNS1 UCSF GRCh37 15 56736723 56736723 + frameshift_variant Frame_Shift_Del DEL T T - 1000g2010nov_all P24_Rec1 Untested WXS Illumina HiSeq 6 0 ENST00000260453.3:c.605del p.Lys202SerfsTer9 p.K202Sfs*9 ENST00000260453 NM_018365.2 202 aAg/ag 0 +MS4A6E UCSF GRCh37 11 60105330 60105330 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0042 P24_Rec1 Untested WXS Illumina HiSeq 157 18 193 0 ENST00000300182.4:c.264C>T p.Asp88= p.D88= ENST00000300182 NM_139249.2 88 gaC/gaT 0 +MTUS1 UCSF GRCh37 8 17504501 17504501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 257 49 269 0 ENST00000262102.6:c.3589G>A p.Ala1197Thr p.A1197T ENST00000262102 NM_001001924.2 1197 Gca/Aca 0 +PREX1 UCSF GRCh37 20 47274678 47274678 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec1 Untested WXS Illumina HiSeq 733 84 686 0 ENST00000371941.3:c.1970C>T p.Ala657Val p.A657V ENST00000371941 NM_020820.3 657 gCt/gTt 0 +PRPH UCSF GRCh37 12 49690754 49690754 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 69 8 36 0 ENST00000257860.4:c.785C>T p.Thr262Met p.T262M ENST00000257860 NM_006262.3 262 aCg/aTg 0 +RC3H1 UCSF GRCh37 1 173933175 173933175 + synonymous_variant Silent SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 80 9 76 0 ENST00000258349.4:c.1767G>A p.Thr589= p.T589= ENST00000258349 NM_172071.2 589 acG/acA 0 +SIGLEC5 UCSF GRCh37 19 52132668 52132668 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.008,1000g2011may_all_0.0309,snp132_rs1807124 P24_Rec1 Untested WXS Illumina HiSeq 23 3 17 0 ENST00000534261.2:c.643A>G p.Met215Val p.M215V ENST00000534261 215 Atg/Gtg 0 +TP53 UCSF GRCh37 17 7576858 7576858 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 25 0 ENST00000269305.4:c.988delC p.Leu330PhefsTer15 p.L330Ffs*15 ENST00000269305 NM_001126112.2 330 Ctt/tt 0 +TRRAP UCSF GRCh37 7 98608691 98608694 + frameshift_variant Frame_Shift_Del DEL TCAA TCAA - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 10 0 ENST00000359863.4:c.10913_10916del p.Leu3638ArgfsTer40 p.L3638Rfs*40 ENST00000359863 NM_001244580.1 3638 cTCAAg/cg 0 +TSKS UCSF GRCh37 19 50265271 50265275 + frameshift_variant Frame_Shift_Del DEL GTGAT GTGAT - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 8 0 ENST00000246801.3:c.385_389del p.Ile129GlyfsTer28 p.I129Gfs*28 ENST00000246801 NM_021733.1 129 ATCACg/g 0 +VGLL1 UCSF GRCh37 X 135630884 135630884 + synonymous_variant Silent SNP G G A NOVEL P24_Rec1 Untested WXS Illumina HiSeq 187 43 207 0 ENST00000370634.3:c.351G>A p.Pro117= p.P117= ENST00000370634 NM_016267.3 117 ccG/ccA 0 +ZNF185 UCSF GRCh37 X 152083371 152083371 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec1 Untested WXS Illumina HiSeq 26 7 17 0 ENST00000370268.4:c.152G>A p.Arg51His p.R51H ENST00000370268 51 cGc/cAc 0 +ZNF286B UCSF GRCh37 17 18565409 18565409 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.010,snp132_rs2530065 P24_Rec1 Untested WXS Illumina HiSeq 20 4 29 1 ENST00000545289.1:c.1410T>C p.Ser470= p.S470= ENST00000545289 NM_001145045.1 470 agT/agC 0 +ZNF324 UCSF GRCh37 19 58982237 58982237 + synonymous_variant Silent SNP G G T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 140 16 124 0 ENST00000196482.3:c.378G>T p.Arg126= p.R126= ENST00000196482 NM_014347.2 126 cgG/cgT 0 +A4GALT UCSF GRCh37 22 43089120 43089120 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 203 26 300 0 ENST00000249005.2:c.838C>T p.Pro280Ser p.P280S ENST00000249005 NM_017436.4 280 Ccc/Tcc 0 +AACS UCSF GRCh37 12 125626687 125626687 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 9 60 0 ENST00000316519.6:c.1931C>T p.Ala644Val p.A644V ENST00000316519 NM_023928.3 644 gCt/gTt 0 +AACS UCSF GRCh37 12 125561117 125561117 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 3 37 0 ENST00000316519.6:c.318G>A p.Leu106= p.L106= ENST00000316519 NM_023928.3 106 ctG/ctA 0 +AASS UCSF GRCh37 7 121755269 121755269 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 22 205 0 ENST00000393376.1:c.902C>T p.Pro301Leu p.P301L ENST00000393376 301 cCc/cTc 0 +ABCA10 UCSF GRCh37 17 67190083 67190083 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 77 404 0 ENST00000269081.4:c.1393G>A p.Glu465Lys p.E465K ENST00000269081 NM_080282.3 465 Gaa/Aaa 0 +ABCA13 UCSF GRCh37 7 48559782 48559782 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 87 275 0 ENST00000435803.1:c.13943C>T p.Pro4648Leu p.P4648L ENST00000435803 NM_152701.3 4648 cCc/cTc 0 +ABCA2 UCSF GRCh37 9 139905759 139905759 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 20 164 0 ENST00000341511.6:c.5802C>T p.Asp1934= p.D1934= ENST00000341511 NM_212533.2 1934 gaC/gaT 0 +ABCA4 UCSF GRCh37 1 94546205 94546205 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 10 99 0 ENST00000370225.3:c.928G>A p.Glu310Lys p.E310K ENST00000370225 NM_000350.2 310 Gag/Aag 0 +ABCA6 UCSF GRCh37 17 67102285 67102285 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 9 94 0 ENST00000284425.2:c.2457C>T p.Ser819= p.S819= ENST00000284425 NM_080284.2 819 tcC/tcT 0 +ABCB1 UCSF GRCh37 7 87160729 87160729 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 20 192 0 ENST00000265724.3:c.2566C>T p.Gln856Ter p.Q856* ENST00000265724 NM_000927.4 856 Caa/Taa 0 +ABCB10 UCSF GRCh37 1 229654102 229654102 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 20 184 0 ENST00000344517.4:c.2041G>A p.Asp681Asn p.D681N ENST00000344517 NM_012089.2 681 Gat/Aat 0 +ABCB11 UCSF GRCh37 2 169833173 169833173 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 8 113 0 ENST00000263817.6:c.1222G>A p.Glu408Lys p.E408K ENST00000263817 NM_003742.2 408 Gaa/Aaa 0 +ABCB11 UCSF GRCh37 2 169788987 169788987 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 11 61 0 ENST00000263817.6:c.3113C>T p.Thr1038Ile p.T1038I ENST00000263817 NM_003742.2 1038 aCc/aTc 0 +ABCB11 UCSF GRCh37 2 169792807 169792807 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 12 78 0 ENST00000263817.6:c.2747C>T p.Ala916Val p.A916V ENST00000263817 NM_003742.2 916 gCc/gTc 0 +ABCB4 UCSF GRCh37 7 87049328 87049328 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 34 247 0 ENST00000265723.4:c.2380G>A p.Ala794Thr p.A794T ENST00000265723 NM_000443.3 794 Gca/Aca 0 +ABCB5 UCSF GRCh37 7 20766690 20766690 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 37 0 ENST00000404938.2:c.2653C>T p.Arg885Cys p.R885C ENST00000404938 NM_001163941.1 885 Cgt/Tgt 0 +ABCC4 UCSF GRCh37 13 95696034 95696034 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 10 88 0 ENST00000376887.4:c.3637G>A p.Glu1213Lys p.E1213K ENST00000376887 NM_005845.3 1213 Gag/Aag 0 +ABCC6 UCSF GRCh37 16 16284056 16284056 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 5 47 0 ENST00000205557.7:c.1600G>A p.Val534Met p.V534M ENST00000205557 NM_001171.5 534 Gtg/Atg 0 +ABCC8 UCSF GRCh37 11 17449921 17449921 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 16 149 0 ENST00000389817.3:c.1955C>T p.Ala652Val p.A652V ENST00000389817 652 gCc/gTc 0 +ABCD1 UCSF GRCh37 X 153002673 153002673 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 5 40 0 ENST00000218104.3:c.1456G>A p.Gly486Arg p.G486R ENST00000218104 NM_000033.3 486 Gga/Aga 0 +ABCD2 UCSF GRCh37 12 40012872 40012872 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0042,snp132_rs35217341 P24_Rec2 Untested WXS Illumina HiSeq 225 31 263 0 ENST00000308666.3:c.546C>T p.His182= p.H182= ENST00000308666 NM_005164.3 182 caC/caT 0 +ABCD4 UCSF GRCh37 14 74761851 74761851 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 211 26 309 0 ENST00000356924.4:c.719G>A p.Arg240Lys p.R240K ENST00000356924 NM_005050.3 240 aGa/aAa 0 +ABCF1 UCSF GRCh37 6 30547723 30547723 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 3 25 0 ENST00000326195.8:c.505C>T p.Gln169Ter p.Q169* ENST00000326195 NM_001025091.1 169 Cag/Tag 0 +ABCF1 UCSF GRCh37 6 30550959 30550959 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 15 123 0 ENST00000326195.8:c.909C>T p.Asp303= p.D303= ENST00000326195 NM_001025091.1 303 gaC/gaT 0 +ABCF1 UCSF GRCh37 6 30553437 30553437 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 9 106 0 ENST00000326195.8:c.1578C>T p.Leu526= p.L526= ENST00000326195 NM_001025091.1 526 ctC/ctT 0 +ABCF3 UCSF GRCh37 3 183905677 183905677 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 10 85 0 ENST00000429586.2:c.475G>A p.Ala159Thr p.A159T ENST00000429586 NM_018358.2 159 Gca/Aca 0 +ABCF3 UCSF GRCh37 3 183910922 183910922 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 18 136 0 ENST00000429586.2:c.1783G>A p.Gly595Ser p.G595S ENST00000429586 NM_018358.2 595 Ggt/Agt 0 +ABCG8 UCSF GRCh37 2 44079759 44079759 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 27 318 0 ENST00000272286.2:c.716C>T p.Pro239Leu p.P239L ENST00000272286 NM_022437.2 239 cCc/cTc 0 +ABHD4 UCSF GRCh37 14 23072957 23072957 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 12 89 0 ENST00000428304.2:c.613G>A p.Ala205Thr p.A205T ENST00000428304 NM_022060.2 205 Gct/Act 0 +ABI3BP UCSF GRCh37 3 100568891 100568891 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 18 124 0 ENST00000284322.5:c.1373C>T p.Pro458Leu p.P458L ENST00000284322 NM_015429.3 458 cCt/cTt 0 +ABL1 UCSF GRCh37 9 133738375 133738375 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 6 47 0 ENST00000318560.5:c.775G>A p.Gly259Ser p.G259S ENST00000318560 NM_005157.4 259 Ggc/Agc 0 +ABRA UCSF GRCh37 8 107781887 107781887 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 73 249 0 ENST00000311955.3:c.532G>A p.Glu178Lys p.E178K ENST00000311955 NM_139166.4 178 Gag/Aag 0 +ACACA UCSF GRCh37 17 35518718 35518718 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 51 0 ENST00000353139.5:c.5326G>A p.Val1776Ile p.V1776I ENST00000353139 NM_198834.1 1776 Gta/Ata 0 +ACACB UCSF GRCh37 12 109623490 109623490 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 15 171 0 ENST00000338432.7:c.1925C>T p.Pro642Leu p.P642L ENST00000338432 642 cCc/cTc 0 +ACACB UCSF GRCh37 12 109629491 109629491 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 21 196 0 ENST00000338432.7:c.2218C>T p.Leu740Phe p.L740F ENST00000338432 740 Ctc/Ttc 0 +ACAD11 UCSF GRCh37 3 132360879 132360879 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 37 268 0 ENST00000264990.6:c.474C>T p.Ser158= p.S158= ENST00000264990 NM_032169.4 158 tcC/tcT 0 +ACAP1 UCSF GRCh37 17 7252391 7252391 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 21 154 0 ENST00000158762.3:c.1756C>T p.Pro586Ser p.P586S ENST00000158762 NM_014716.3 586 Ccc/Tcc 0 +ACBD6 UCSF GRCh37 1 180471299 180471299 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 273 43 366 0 ENST00000367595.3:c.103G>A p.Glu35Lys p.E35K ENST00000367595 NM_032360.3 35 Gag/Aag 0 +ACCN2 UCSF GRCh37 12 50474479 50474479 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 17 163 0 ENST00000447966.2:c.1297+107C>T *433* ENST00000447966 NM_001095.3 0 +ACE UCSF GRCh37 17 61557699 61557699 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 12 47 0 ENST00000290866.4:c.657C>T p.Gly219= p.G219= ENST00000290866 NM_000789.3 219 ggC/ggT 0 +ACSBG1 UCSF GRCh37 15 78526734 78526734 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 31 214 0 ENST00000258873.4:c.110C>T p.Thr37Ile p.T37I ENST00000258873 NM_001199377.1 37 aCc/aTc 0 +ACSS2 UCSF GRCh37 20 33470605 33470605 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 75 0 ENST00000360596.2:c.187G>A p.Gly63Arg p.G63R ENST00000360596 NM_018677.3 63 Gga/Aga 0 +ACSS2 UCSF GRCh37 20 33507237 33507237 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 29 178 0 ENST00000360596.2:c.835-1G>A p.X279_splice ENST00000360596 NM_018677.3 0 +ACTA1 UCSF GRCh37 1 229568828 229568828 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 48 0 ENST00000366684.3:c.35G>A p.Cys12Tyr p.C12Y ENST00000366684 NM_001100.3 12 tGc/tAc 0 +ACTB UCSF GRCh37 7 5567397 5567397 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 9 0 ENST00000331789.5:c.1110C>T p.Val370= p.V370= ENST00000331789 NM_001101.3 370 gtC/gtT 0 +ACTL7B UCSF GRCh37 9 111616998 111616998 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 19 163 0 ENST00000374667.3:c.1213G>A p.Glu405Lys p.E405K ENST00000374667 NM_006686.3 405 Gag/Aag 0 +ACTL7B UCSF GRCh37 9 111617665 111617665 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 28 257 0 ENST00000374667.3:c.546G>A p.Ser182= p.S182= ENST00000374667 NM_006686.3 182 tcG/tcA 0 +ACTL8 UCSF GRCh37 1 18152819 18152819 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 33 229 0 ENST00000375406.1:c.906C>T p.Thr302= p.T302= ENST00000375406 NM_030812.2 302 acC/acT 0 +ACTN4 UCSF GRCh37 19 39214964 39214964 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 23 126 0 ENST00000252699.2:c.1860C>T p.Asn620= p.N620= ENST00000252699 NM_004924.4 620 aaC/aaT 0 +ACTR5 UCSF GRCh37 20 37380900 37380900 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 9 60 0 ENST00000243903.4:c.732G>A p.Glu244= p.E244= ENST00000243903 NM_024855.3 244 gaG/gaA 0 +ACVR1B UCSF GRCh37 12 52387891 52387891 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 10 52 0 ENST00000257963.4:c.1515C>T p.Ile505= p.I505= ENST00000257963 NM_020328.3 505 atC/atT 0 +ADAM12 UCSF GRCh37 10 127753543 127753543 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 5 38 0 ENST00000368679.4:c.1450G>A p.Asp484Asn p.D484N ENST00000368679 NM_003474.4 484 Gac/Aac 0 +ADAM12 UCSF GRCh37 10 127760187 127760187 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 192 50 445 0 ENST00000368679.4:c.1191G>A p.Arg397= p.R397= ENST00000368679 NM_003474.4 397 agG/agA 0 +ADAM17 UCSF GRCh37 2 9630458 9630458 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 58 172 0 ENST00000310823.3:c.2323G>A p.Asp775Asn p.D775N ENST00000310823 NM_003183.4 775 Gat/Aat 0 +ADAM22 UCSF GRCh37 7 87760657 87760657 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 192 33 300 0 ENST00000265727.7:c.899C>T p.Ala300Val p.A300V ENST00000265727 300 gCc/gTc 0 +ADAM9 UCSF GRCh37 8 38913251 38913251 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 37 177 0 ENST00000487273.2:c.1551C>T p.Cys517= p.C517= ENST00000487273 NM_003816.2 517 tgC/tgT 0 +ADAMTS1 UCSF GRCh37 21 28217227 28217227 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 27 189 0 ENST00000284984.3:c.47G>A p.Ser16Asn p.S16N ENST00000284984 NM_006988.3 16 aGc/aAc 0 +ADAMTS13 UCSF GRCh37 9 136310022 136310022 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 36 108 0 ENST00000371929.3:c.2459G>A p.Gly820Asp p.G820D ENST00000371929 NM_139025.4 820 gGt/gAt 0 +ADAMTS13 UCSF GRCh37 9 136314999 136314999 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 30 0 ENST00000371929.3:c.2957G>A p.Gly986Asp p.G986D ENST00000371929 NM_139025.4 986 gGt/gAt 0 +ADAMTS18 UCSF GRCh37 16 77396097 77396097 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 10 76 0 ENST00000282849.5:c.1121C>T p.Ala374Val p.A374V ENST00000282849 NM_199355.2 374 gCc/gTc 0 +ADAMTS19 UCSF GRCh37 5 128983457 128983457 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 22 215 0 ENST00000274487.4:c.1855-1G>A p.X619_splice ENST00000274487 NM_133638.3 0 +ADAMTS5 UCSF GRCh37 21 28296430 28296430 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 391 60 490 0 ENST00000284987.5:c.2735G>A p.Gly912Glu p.G912E ENST00000284987 NM_007038.3 912 gGa/gAa 0 +ADAMTS6 UCSF GRCh37 5 64766794 64766794 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 38 277 0 ENST00000381055.3:c.273C>T p.Ala91= p.A91= ENST00000381055 NM_197941.2 91 gcC/gcT 0 +ADCK2 UCSF GRCh37 7 140373796 140373796 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 35 207 0 ENST00000072869.4:c.666C>T p.Ala222= p.A222= ENST00000072869 NM_052853.3 222 gcC/gcT 0 +ADCY10 UCSF GRCh37 1 167805696 167805696 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 9 84 0 ENST00000367851.4:c.3160C>T p.Pro1054Ser p.P1054S ENST00000367851 NM_018417.4 1054 Cct/Tct 0 +ADCY10 UCSF GRCh37 1 167852699 167852699 + synonymous_variant Silent SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 33 135 0 ENST00000367851.4:c.996C>A p.Ile332= p.I332= ENST00000367851 NM_018417.4 332 atC/atA 0 +ADCY8 UCSF GRCh37 8 132052082 132052082 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 21 101 0 ENST00000286355.5:c.498G>A p.Leu166= p.L166= ENST00000286355 NM_001115.2 166 ttG/ttA 0 +ADD2 UCSF GRCh37 2 70900457 70900457 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 18 150 0 ENST00000264436.4:c.1742-319G>A *581* ENST00000264436 NM_001617.3 0 +ADRBK1 UCSF GRCh37 11 67050605 67050605 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 143 404 0 ENST00000308595.5:c.1234G>A p.Glu412Lys p.E412K ENST00000308595 NM_001619.3 412 Gag/Aag 0 +ADRBK1 UCSF GRCh37 11 67049810 67049810 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 21 128 0 ENST00000308595.5:c.1026C>T p.Phe342= p.F342= ENST00000308595 NM_001619.3 342 ttC/ttT 0 +AEN UCSF GRCh37 15 89172585 89172585 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 40 0 ENST00000332810.3:c.669G>A p.Glu223= p.E223= ENST00000332810 NM_022767.3 223 gaG/gaA 0 +AFAP1 UCSF GRCh37 4 7802206 7802206 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 27 255 0 ENST00000358461.2:c.1229G>A p.Arg410Gln p.R410Q ENST00000358461 NM_198595.2 410 cGg/cAg 0 +AFAP1 UCSF GRCh37 4 7774616 7774616 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 228 43 320 0 ENST00000358461.2:c.1932G>A p.Lys644= p.K644= ENST00000358461 NM_198595.2 644 aaG/aaA 0 +AFAP1L2 UCSF GRCh37 10 116064684 116064684 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 4 45 0 ENST00000304129.4:c.1078C>T p.Leu360= p.L360= ENST00000304129 NM_001287824.1 360 Ctg/Ttg 0 +AFF3 UCSF GRCh37 2 100203737 100203737 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 21 197 0 ENST00000409236.2:c.2470G>A p.Asp824Asn p.D824N ENST00000409236 824 Gac/Aac 0 +AGER UCSF GRCh37 6 32151714 32151714 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 26 192 0 ENST00000375076.4:c.103G>A p.Val35Met p.V35M ENST00000375076 NM_001206929.1 35 Gtg/Atg 0 +AGFG2 UCSF GRCh37 7 100159897 100159897 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.0012 P24_Rec2 Untested WXS Illumina HiSeq 51 9 85 0 ENST00000300176.4:c.893C>T p.Thr298Ile p.T298I ENST00000300176 NM_006076.4 298 aCt/aTt 0 +AGK UCSF GRCh37 7 141349127 141349127 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 281 37 294 0 ENST00000355413.4:c.1040C>T p.Thr347Ile p.T347I ENST00000355413 NM_018238.3 347 aCt/aTt 0 +AGL UCSF GRCh37 1 100335995 100335995 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 31 263 0 ENST00000294724.4:c.704C>T p.Ala235Val p.A235V ENST00000294724 NM_000028.2 235 gCc/gTc 0 +AHNAK2 UCSF GRCh37 14 105404793 105404793 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 23 198 0 ENST00000333244.5:c.16995C>T p.Ser5665= p.S5665= ENST00000333244 NM_138420.2 5665 tcC/tcT 0 +AIF1 UCSF GRCh37 6 31583111 31583111 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 23 72 0 ENST00000376059.3:c.5G>A p.Ser2Asn p.S2N ENST00000376059 NM_001623.3 2 aGc/aAc 0 +AIM1L UCSF GRCh37 1 26670384 26670384 + 5_prime_UTR_variant 5'UTR SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 15 159 0 ENST00000308182.5:c.-371C>T *124* ENST00000308182 0 +AIM2 UCSF GRCh37 1 159036072 159036072 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 22 170 0 ENST00000368130.4:c.444G>A p.Gly148= p.G148= ENST00000368130 NM_004833.1 148 ggG/ggA 0 +AK5 UCSF GRCh37 1 77752629 77752629 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 5 68 0 ENST00000354567.2:c.64C>T p.Leu22Phe p.L22F ENST00000354567 NM_174858.2 22 Ctt/Ttt 0 +AKAP13 UCSF GRCh37 15 86123161 86123161 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 24 221 0 ENST00000394518.2:c.1862C>T p.Ala621Val p.A621V ENST00000394518 NM_007200.4 621 gCc/gTc 0 +AKAP3 UCSF GRCh37 12 4736308 4736308 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 120 211 1 ENST00000228850.1:c.1760A>G p.Lys587Arg p.K587R ENST00000228850 587 aAg/aGg 0 +AKAP4 UCSF GRCh37 X 49958781 49958781 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 27 152 0 ENST00000358526.2:c.583C>T p.Pro195Ser p.P195S ENST00000358526 NM_003886.2 195 Cca/Tca 0 +AKAP5 UCSF GRCh37 14 64935379 64935379 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 36 350 0 ENST00000320636.5:c.267G>A p.Arg89= p.R89= ENST00000320636 89 agG/agA 0 +AKAP6 UCSF GRCh37 14 33046377 33046377 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 14 103 0 ENST00000280979.4:c.2398G>A p.Glu800Lys p.E800K ENST00000280979 NM_004274.4 800 Gaa/Aaa 0 +AKAP8 UCSF GRCh37 19 15479045 15479045 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 725 86 656 0 ENST00000269701.2:c.1160+1G>A p.X387_splice ENST00000269701 NM_005858.3 0 +ALAS1 UCSF GRCh37 3 52240740 52240740 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 283 37 411 0 ENST00000310271.2:c.1138G>A p.Ala380Thr p.A380T ENST00000310271 NM_199166.2 380 Gca/Aca 0 +ALDH1L1 UCSF GRCh37 3 125833449 125833449 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 18 152 0 ENST00000393434.2:c.2033C>T p.Ser678Leu p.S678L ENST00000393434 NM_012190.3 678 tCa/tTa 0 +ALDH1L1 UCSF GRCh37 3 125879707 125879707 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 13 72 0 ENST00000393434.2:c.116C>T p.Ala39Val p.A39V ENST00000393434 NM_012190.3 39 gCc/gTc 0 +ALDH6A1 UCSF GRCh37 14 74531550 74531550 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 27 247 0 ENST00000553458.1:c.1478G>A p.Gly493Glu p.G493E ENST00000553458 NM_001278593.1 493 gGa/gAa 0 +ALG2 UCSF GRCh37 9 101980970 101980970 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 6 74 0 ENST00000476832.1:c.497C>T p.Thr166Ile p.T166I ENST00000476832 NM_033087.3 166 aCc/aTc 0 +ALKBH2 UCSF GRCh37 12 109526108 109526108 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 12 114 0 ENST00000343075.3:c.689C>T p.Thr230Ile p.T230I ENST00000343075 NM_001001655.2 230 aCc/aTc 0 +ALLC UCSF GRCh37 2 3749131 3749131 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 8 66 0 ENST00000252505.3:c.880G>A p.Gly294Arg p.G294R ENST00000252505 NM_018436.3 294 Ggg/Agg 0 +ALMS1 UCSF GRCh37 2 73676891 73676891 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 443 76 650 0 ENST00000264448.6:c.3234C>T p.Phe1078= p.F1078= ENST00000264448 NM_015120.4 1078 ttC/ttT 0 +ALMS1 UCSF GRCh37 2 73800038 73800038 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 12 118 0 ENST00000264448.6:c.11031G>A p.Arg3677= p.R3677= ENST00000264448 NM_015120.4 3677 cgG/cgA 0 +ALPI UCSF GRCh37 2 233321741 233321741 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 47 0 ENST00000295463.3:c.433G>A p.Gly145Ser p.G145S ENST00000295463 NM_001631.3 145 Ggc/Agc 0 +ALPK1 UCSF GRCh37 4 113352584 113352584 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 45 482 0 ENST00000177648.9:c.1881G>A p.Glu627= p.E627= ENST00000177648 627 gaG/gaA 0 +ALPK2 UCSF GRCh37 18 56205132 56205132 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 282 47 354 0 ENST00000361673.3:c.2287G>A p.Asp763Asn p.D763N ENST00000361673 NM_052947.3 763 Gat/Aat 0 +ALPK2 UCSF GRCh37 18 56246191 56246191 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 209 122 444 0 ENST00000361673.3:c.1817C>T p.Thr606Ile p.T606I ENST00000361673 NM_052947.3 606 aCc/aTc 0 +ALPL UCSF GRCh37 1 21894608 21894608 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 41 144 0 ENST00000374832.1:c.660G>A p.Gly220= p.G220= ENST00000374832 220 ggG/ggA 0 +ALX4 UCSF GRCh37 11 44286642 44286642 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 12 80 0 ENST00000329255.3:c.998C>T p.Ser333Phe p.S333F ENST00000329255 NM_021926.3 333 tCc/tTc 0 +AMDHD1 UCSF GRCh37 12 96354252 96354252 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 26 303 0 ENST00000266736.2:c.664G>A p.Gly222Arg p.G222R ENST00000266736 NM_152435.2 222 Ggg/Agg 0 +AMHR2 UCSF GRCh37 12 53825207 53825207 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 603 97 843 0 ENST00000257863.4:c.1672G>A p.Gly558Ser p.G558S ENST00000257863 NM_001164690.1 558 Ggc/Agc 0 +AMPD2 UCSF GRCh37 1 110167963 110167963 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 248 53 320 0 ENST00000256578.3:c.292G>A p.Ala98Thr p.A98T ENST00000256578 NM_004037.7 98 Gcc/Acc 0 +ANGPTL5 UCSF GRCh37 11 101773398 101773398 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 17 228 0 ENST00000334289.3:c.494G>A p.Ser165Asn p.S165N ENST00000334289 NM_178127.4 165 aGt/aAt 0 +ANKAR UCSF GRCh37 2 190595295 190595295 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 12 115 0 ENST00000313581.4:c.3268C>T p.Leu1090= p.L1090= ENST00000313581 1090 Cta/Tta 0 +ANKHD1 UCSF GRCh37 5 139838875 139838875 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 8 97 0 ENST00000360839.2:c.1607C>T p.Ser536Phe p.S536F ENST00000360839 NM_017747.2 536 tCc/tTc 0 +ANKLE1 UCSF GRCh37 19 17394429 17394429 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 384 47 372 0 ENST00000394458.3:c.856G>A p.Ala286Thr p.A286T ENST00000394458 NM_001278444.1 286 Gct/Act 0 +ANKRD13D UCSF GRCh37 11 67059142 67059142 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 36 271 0 ENST00000308440.6:c.205G>A p.Val69Ile p.V69I ENST00000308440 69 Gta/Ata 0 +ANKRD40 UCSF GRCh37 17 48776819 48776819 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 12 61 0 ENST00000285243.6:c.719G>A p.Gly240Glu p.G240E ENST00000285243 NM_052855.3 240 gGa/gAa 0 +ANKRD44 UCSF GRCh37 2 197946370 197946370 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 3 33 0 ENST00000282272.8:c.1513C>T p.Leu505= p.L505= ENST00000282272 NM_001195144.1 505 Cta/Tta 0 +ANKS1B UCSF GRCh37 12 99548209 99548209 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 12 58 0 ENST00000547776.2:c.2420-36C>T *807* ENST00000547776 NM_152788.4 0 +ANKS3 UCSF GRCh37 16 4752160 4752160 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 10 48 0 ENST00000304283.4:c.952G>A p.Val318Ile p.V318I ENST00000304283 NM_133450.3 318 Gtc/Atc 0 +ANO2 UCSF GRCh37 12 5685114 5685114 + missense_variant Missense_Mutation SNP T T A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 280 73 228 0 ENST00000356134.5:c.2510A>T p.Asn837Ile p.N837I ENST00000356134 837 aAt/aTt 0 +ANTXR1 UCSF GRCh37 2 69330008 69330008 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 14 132 0 ENST00000303714.4:c.738C>T p.Phe246= p.F246= ENST00000303714 NM_032208.2 246 ttC/ttT 0 +ANTXR2 UCSF GRCh37 4 80992803 80992803 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 25 275 0 ENST00000307333.7:c.158G>A p.Gly53Glu p.G53E ENST00000307333 NM_001145794.1 53 gGg/gAg 0 +AOC3 UCSF GRCh37 17 41004671 41004671 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 209 29 329 0 ENST00000308423.2:c.1311C>T p.Gly437= p.G437= ENST00000308423 NM_003734.3 437 ggC/ggT 0 +AP3B1 UCSF GRCh37 5 77452093 77452093 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 229 30 388 0 ENST00000255194.6:c.1462G>A p.Asp488Asn p.D488N ENST00000255194 488 Gac/Aac 0 +AP3B2 UCSF GRCh37 15 83349459 83349459 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 43 210 0 ENST00000261722.3:c.820G>A p.Glu274Lys p.E274K ENST00000261722 NM_004644.4 274 Gag/Aag 0 +AP3D1 UCSF GRCh37 19 2115382 2115382 + missense_variant Missense_Mutation SNP C C T snp132_rs34098352 P24_Rec2 Untested WXS Illumina HiSeq 402 45 371 0 ENST00000345016.5:c.2185G>A p.Glu729Lys p.E729K ENST00000345016 NM_003938.6 729 Gag/Aag 0 +AP3D1 UCSF GRCh37 19 2110730 2110730 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 28 0 ENST00000345016.5:c.2965C>T p.Pro989Ser p.P989S ENST00000345016 NM_003938.6 989 Ccc/Tcc 0 +AP4B1 UCSF GRCh37 1 114438498 114438498 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 18 149 0 ENST00000256658.4:c.1673C>T p.Ser558Leu p.S558L ENST00000256658 NM_006594.3 558 tCa/tTa 0 +APBA1 UCSF GRCh37 9 72067119 72067119 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 23 258 0 ENST00000265381.4:c.1887G>A p.Lys629= p.K629= ENST00000265381 NM_001163.3 629 aaG/aaA 0 +APEH UCSF GRCh37 3 49713502 49713502 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 337 62 424 0 ENST00000296456.5:c.456C>T p.Cys152= p.C152= ENST00000296456 NM_001640.3 152 tgC/tgT 0 +APH1B UCSF GRCh37 15 63597957 63597957 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 275 39 393 0 ENST00000261879.5:c.751C>T p.Leu251Phe p.L251F ENST00000261879 NM_031301.3 251 Ctt/Ttt 0 +APITD1 UCSF GRCh37 1 10500457 10500457 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 8 93 0 ENST00000309048.3:c.263G>A p.Arg88Lys p.R88K ENST00000309048 NM_199294.2 88 aGg/aAg 0 +APLF UCSF GRCh37 2 68753356 68753356 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 15 106 0 ENST00000303795.4:c.786G>A p.Glu262= p.E262= ENST00000303795 NM_173545.2 262 gaG/gaA 0 +APLNR UCSF GRCh37 11 57003475 57003475 + missense_variant,NMD_transcript_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 42 273 0 ENST00000257254.3:c.1004C>T p.Ser335Phe p.S335F ENST00000257254 335 tCc/tTc 0 +APOA5 UCSF GRCh37 11 116660927 116660927 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 31 209 0 ENST00000227665.4:c.1018C>T p.Leu340= p.L340= ENST00000227665 340 Ctg/Ttg 0 +APOB UCSF GRCh37 2 21228815 21228815 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 270 51 391 0 ENST00000233242.1:c.10925G>A p.Gly3642Glu p.G3642E ENST00000233242 NM_000384.2 3642 gGg/gAg 0 +APOB UCSF GRCh37 2 21236226 21236226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 45 171 1 ENST00000233242.1:c.4022C>T p.Thr1341Ile p.T1341I ENST00000233242 NM_000384.2 1341 aCc/aTc 0 +APOBEC3B UCSF GRCh37 22 39382097 39382097 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 10 93 0 ENST00000333467.3:c.454+1G>A p.X152_splice ENST00000333467 NM_004900.4 0 +APOD UCSF GRCh37 3 195295876 195295876 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 31 117 0 ENST00000343267.3:c.465C>T p.Leu155= p.L155= ENST00000343267 NM_001647.3 155 ctC/ctT 0 +APOH UCSF GRCh37 17 64210600 64210600 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 21 203 0 ENST00000205948.6:c.953G>A p.Gly318Asp p.G318D ENST00000205948 NM_000042.2 318 gGc/gAc 0 +APOL3 UCSF GRCh37 22 36537471 36537471 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 177 34 260 0 ENST00000349314.2:c.986C>T p.Thr329Ile p.T329I ENST00000349314 NM_145640.2 329 aCc/aTc 0 +APOL4 UCSF GRCh37 22 36587897 36587897 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 36 307 0 ENST00000352371.1:c.280G>A p.Asp94Asn p.D94N ENST00000352371 94 Gac/Aac 0 +APOL6 UCSF GRCh37 22 36055273 36055273 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 21 139 0 ENST00000409652.4:c.662C>T p.Ala221Val p.A221V ENST00000409652 NM_030641.3 221 gCc/gTc 0 +APPL1 UCSF GRCh37 3 57291453 57291453 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 20 188 0 ENST00000288266.3:c.1427G>A p.Gly476Asp p.G476D ENST00000288266 NM_012096.2 476 gGc/gAc 0 +AQP10 UCSF GRCh37 1 154295472 154295472 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 82 0 ENST00000324978.3:c.247C>T p.Pro83Ser p.P83S ENST00000324978 NM_080429.2 83 Cca/Tca 0 +ARAP3 UCSF GRCh37 5 141036200 141036200 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 17 122 0 ENST00000239440.4:c.3660C>T p.Ile1220= p.I1220= ENST00000239440 NM_022481.5 1220 atC/atT 0 +ARC UCSF GRCh37 8 143694825 143694825 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 21 252 0 ENST00000356613.2:c.808G>A p.Glu270Lys p.E270K ENST00000356613 NM_015193.4 270 Gag/Aag 0 +ARHGAP20 UCSF GRCh37 11 110477462 110477462 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 16 199 0 ENST00000260283.4:c.787C>T p.Pro263Ser p.P263S ENST00000260283 NM_020809.3 263 Cca/Tca 0 +ARHGAP28 UCSF GRCh37 18 6896535 6896535 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 10 120 0 ENST00000383472.4:c.1940C>T p.Ala647Val p.A647V ENST00000383472 647 gCt/gTt 0 +ARHGAP29 UCSF GRCh37 1 94645456 94645456 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 16 113 0 ENST00000260526.6:c.2305G>A p.Glu769Lys p.E769K ENST00000260526 NM_004815.3 769 Gag/Aag 0 +ARHGAP30 UCSF GRCh37 1 161021503 161021503 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 16 108 0 ENST00000368013.3:c.1021C>T p.Pro341Ser p.P341S ENST00000368013 NM_181720.2 341 Cca/Tca 0 +ARHGAP39 UCSF GRCh37 8 145773405 145773405 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 41 245 0 ENST00000276826.5:c.1065G>A p.Pro355= p.P355= ENST00000276826 355 ccG/ccA 0 +ARHGAP44 UCSF GRCh37 17 12887937 12887937 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 28 194 0 ENST00000379672.5:c.2029G>A p.Val677Ile p.V677I ENST00000379672 NM_014859.4 677 Gtc/Atc 0 +ARHGAP6 UCSF GRCh37 X 11157559 11157559 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 9 51 0 ENST00000337414.4:c.2349G>A p.Trp783Ter p.W783* ENST00000337414 NM_013427.2 783 tgG/tgA 0 +ARHGAP9 UCSF GRCh37 12 57871385 57871385 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 308 40 33 0 ENST00000393791.3:c.613C>T p.Pro205Ser p.P205S ENST00000393791 NM_032496.2 205 Ccc/Tcc 0 +ARHGEF16 UCSF GRCh37 1 3386008 3386008 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 12 111 0 ENST00000378378.4:c.873G>A p.Glu291= p.E291= ENST00000378378 NM_014448.3 291 gaG/gaA 0 +ARHGEF18 UCSF GRCh37 19 7516038 7516038 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 38 174 0 ENST00000359920.6:c.1177A>T p.Ile393Phe p.I393F ENST00000359920 NM_001130955.1 393 Att/Ttt 0 +ARHGEF2 UCSF GRCh37 1 155935512 155935512 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 4 42 0 ENST00000361247.4:c.380C>T p.Ser127Phe p.S127F ENST00000361247 NM_001162384.1 127 tCc/tTc 0 +ARHGEF26 UCSF GRCh37 3 153840604 153840604 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 12 67 0 ENST00000356448.4:c.823C>T p.Leu275Phe p.L275F ENST00000356448 NM_001251962.1 275 Ctc/Ttc 0 +ARHGEF33 UCSF GRCh37 2 39178263 39178263 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 187 23 245 0 ENST00000409978.1:c.1053+1G>A p.X351_splice ENST00000409978 0 +ARHGEF38 UCSF GRCh37 4 106588455 106588455 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 97 340 0 ENST00000420470.2:c.1859G>A p.Ser620Asn p.S620N ENST00000420470 NM_001242729.1 620 aGt/aAt 0 +ARHGEF7 UCSF GRCh37 13 111935647 111935647 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 8 50 0 ENST00000375741.2:c.1950G>A p.Trp650Ter p.W650* ENST00000375741 NM_145735.2 650 tgG/tgA 0 +ARID1B UCSF GRCh37 6 157527695 157527695 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 37 136 0 ENST00000350026.5:c.5381G>A p.Gly1794Glu p.G1794E ENST00000350026 NM_017519.2 1794 gGg/gAg 0 +ARMC2 UCSF GRCh37 6 109294624 109294624 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 16 175 0 ENST00000392644.4:c.2511G>A p.Trp837Ter p.W837* ENST00000392644 NM_032131.4 837 tgG/tgA 0 +ARMC2 UCSF GRCh37 6 109190146 109190146 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 12 111 0 ENST00000392644.4:c.411G>A p.Arg137= p.R137= ENST00000392644 NM_032131.4 137 agG/agA 0 +ARMC4 UCSF GRCh37 10 28151470 28151470 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 20 137 0 ENST00000305242.5:c.2692C>T p.Leu898= p.L898= ENST00000305242 NM_018076.2 898 Ctg/Ttg 0 +ARMC6 UCSF GRCh37 19 19153577 19153577 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 32 224 0 ENST00000392336.3:c.87G>A p.Lys29= p.K29= ENST00000392336 29 aaG/aaA 0 +ARMC8 UCSF GRCh37 3 138003305 138003305 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 24 228 0 ENST00000469044.1:c.1758G>A p.Gly586= p.G586= ENST00000469044 NM_001267041.1 586 ggG/ggA 0 +ARMCX2 UCSF GRCh37 X 100910957 100910957 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 32 149 0 ENST00000328766.5:c.1618G>A p.Asp540Asn p.D540N ENST00000328766 NM_014782.5 540 Gat/Aat 0 +ARNT UCSF GRCh37 1 150786699 150786699 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 27 232 0 ENST00000358595.5:c.1967C>T p.Ala656Val p.A656V ENST00000358595 NM_178427.2 656 gCt/gTt 0 +ARPP19 UCSF GRCh37 15 52849334 52849334 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 19 114 0 ENST00000249822.4:c.131G>A p.Gly44Glu p.G44E ENST00000249822 NM_006628.4 44 gGa/gAa 0 +ARPP21 UCSF GRCh37 3 35785374 35785374 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 18 185 0 ENST00000187397.4:c.1949C>T p.Thr650Ile p.T650I ENST00000187397 NM_016300.4 650 aCc/aTc 0 +ARRB1 UCSF GRCh37 11 74985189 74985189 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 12 99 0 ENST00000420843.2:c.843C>T p.Asn281= p.N281= ENST00000420843 NM_004041.4 281 aaC/aaT 0 +ARRDC2 UCSF GRCh37 19 18112378 18112378 + downstream_gene_variant 3'Flank SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 7 62 0 ENST00000222249 NM_002248.4 0 +ARSJ UCSF GRCh37 4 114899759 114899759 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 17 184 0 ENST00000315366.7:c.232C>T p.Leu78Phe p.L78F ENST00000315366 NM_024590.3 78 Ctc/Ttc 0 +ARX UCSF GRCh37 X 25031293 25031293 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 42 142 0 ENST00000379044.4:c.819C>T p.Ala273= p.A273= ENST00000379044 NM_139058.2 273 gcC/gcT 0 +ASAP1 UCSF GRCh37 8 131073167 131073167 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 38 164 0 ENST00000518721.1:c.2850C>T p.Pro950= p.P950= ENST00000518721 NM_001247996.1 950 ccC/ccT 0 +ASB10 UCSF GRCh37 7 150878373 150878373 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 208 30 199 0 ENST00000420175.2:c.757C>T p.Leu253= p.L253= ENST00000420175 253 Ctg/Ttg 0 +ASB16 UCSF GRCh37 17 42254374 42254374 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 29 0 ENST00000293414.1:c.838G>A p.Ala280Thr p.A280T ENST00000293414 NM_080863.4 280 Gcc/Acc 0 +ASH1L UCSF GRCh37 1 155451559 155451559 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 342 50 521 0 ENST00000368346.3:c.1102G>A p.Val368Ile p.V368I ENST00000368346 368 Gtt/Att 0 +ASH1L UCSF GRCh37 1 155448314 155448314 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 58 0 ENST00000368346.3:c.4347G>A p.Gln1449= p.Q1449= ENST00000368346 1449 caG/caA 0 +ASNSD1 UCSF GRCh37 2 190531191 190531191 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 161 30 250 0 ENST00000260952.4:c.333C>T p.Leu111= p.L111= ENST00000260952 NM_019048.2 111 ctC/ctT 0 +ASPG UCSF GRCh37 14 104569962 104569962 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 5 34 0 ENST00000551177.1:c.703G>A p.Glu235Lys p.E235K ENST00000551177 NM_001080464.2 235 Gag/Aag 0 +ASPH UCSF GRCh37 8 62438590 62438590 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 16 136 0 ENST00000379454.4:c.1846G>A p.Asp616Asn p.D616N ENST00000379454 NM_004318.3 616 Gat/Aat 0 +ASPM UCSF GRCh37 1 197071895 197071895 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 119 445 0 ENST00000367409.4:c.6486G>C p.Lys2162Asn p.K2162N ENST00000367409 NM_018136.4 2162 aaG/aaC 0 +ASTN2 UCSF GRCh37 9 119249637 119249637 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 3 41 0 ENST00000313400.4:c.3497+1G>A p.X1166_splice ENST00000313400 0 +ASTN2 UCSF GRCh37 9 119976908 119976908 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 16 143 0 ENST00000313400.4:c.744C>T p.Ala248= p.A248= ENST00000313400 248 gcC/gcT 0 +ASXL3 UCSF GRCh37 18 31324781 31324781 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 27 280 0 ENST00000269197.5:c.4969C>T p.Pro1657Ser p.P1657S ENST00000269197 NM_030632.1 1657 Ccc/Tcc 0 +ASXL3 UCSF GRCh37 18 31263528 31263528 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 18 128 0 ENST00000269197.5:c.875G>A p.Arg292Lys p.R292K ENST00000269197 NM_030632.1 292 aGg/aAg 0 +ATAD1 UCSF GRCh37 10 89552427 89552427 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 11 113 0 ENST00000308448.7:c.248C>T p.Pro83Leu p.P83L ENST00000308448 NM_032810.2 83 cCt/cTt 0 +ATAD2B UCSF GRCh37 2 23985174 23985174 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 344 53 428 0 ENST00000238789.5:c.3299G>A p.Gly1100Glu p.G1100E ENST00000238789 NM_001242338.1 1100 gGa/gAa 0 +ATF5 UCSF GRCh37 19 50436164 50436164 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 215 52 298 0 ENST00000423777.2:c.664G>A p.Ala222Thr p.A222T ENST00000423777 NM_001193646.1 222 Gct/Act 0 +ATP12A UCSF GRCh37 13 25266679 25266679 + missense_variant Missense_Mutation SNP G G A snp132_rs112162533 P24_Rec2 Untested WXS Illumina HiSeq 130 17 167 0 ENST00000381946.3:c.1181G>A p.Gly394Glu p.G394E ENST00000381946 394 gGg/gAg 0 +ATP1A1 UCSF GRCh37 1 116930849 116930849 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 0 ENST00000295598.5:c.488del p.Asn163ThrfsTer9 p.N163Tfs*9 ENST00000295598 NM_000701.7 162 Aaa/aa 0 +ATP1B2 UCSF GRCh37 17 7557516 7557516 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 293 44 330 0 ENST00000250111.4:c.493G>A p.Asp165Asn p.D165N ENST00000250111 NM_001678.3 165 Gac/Aac 0 +ATP5J2-PTCD1 UCSF GRCh37 7 99032499 99032499 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 11 109 0 ENST00000292478.4:c.367G>A p.Glu123Lys p.E123K ENST00000292478 NM_015545.3 123 Gaa/Aaa 0 +ATP6AP1 UCSF GRCh37 X 153662579 153662579 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 11 85 0 ENST00000369762.2:c.710C>T p.Ala237Val p.A237V ENST00000369762 NM_001183.4 237 gCc/gTc 0 +ATR UCSF GRCh37 3 142176554 142176554 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 235 37 351 0 ENST00000350721.4:c.7547C>T p.Thr2516Ile p.T2516I ENST00000350721 NM_001184.3 2516 aCt/aTt 0 +ATR UCSF GRCh37 3 142280101 142280101 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 163 24 274 0 ENST00000350721.4:c.1333C>T p.Pro445Ser p.P445S ENST00000350721 NM_001184.3 445 Cca/Tca 0 +ATRN UCSF GRCh37 20 3527970 3527970 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 13 150 0 ENST00000262919.5:c.777G>A p.Glu259= p.E259= ENST00000262919 NM_139321.2 259 gaG/gaA 0 +ATRNL1 UCSF GRCh37 10 116853739 116853739 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 56 150 0 ENST00000355044.3:c.230C>T p.Ser77Phe p.S77F ENST00000355044 NM_207303.2 77 tCc/tTc 0 +ATRX UCSF GRCh37 X 76939340 76939343 + frameshift_variant Frame_Shift_Del DEL CTAC CTAC - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 0 ENST00000373344.5:c.1405_1408delGTAG p.Val469IlefsTer44 p.V469Ifs*44 ENST00000373344 NM_000489.3 469 GTAGat/at 0 +ATXN10 UCSF GRCh37 22 46085607 46085607 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 10 4 26 0 ENST00000252934.5:c.132G>A p.Arg44= p.R44= ENST00000252934 NM_013236.3 44 agG/agA 0 +ATXN2 UCSF GRCh37 12 111956165 111956165 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 23 118 0 ENST00000377617.3:c.1533G>A p.Gln511= p.Q511= ENST00000377617 NM_002973.3 511 caG/caA 0 +ATXN7 UCSF GRCh37 3 63898902 63898902 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 192 35 291 0 ENST00000295900.6:c.394+1G>A p.X132_splice ENST00000295900 NM_000333.3 0 +AUTS2 UCSF GRCh37 7 70255005 70255005 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 17 120 0 ENST00000342771.4:c.2803C>T p.Gln935Ter p.Q935* ENST00000342771 NM_015570.2 935 Cag/Tag 0 +AXIN1 UCSF GRCh37 16 360045 360045 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 10 84 0 ENST00000262320.3:c.1044C>T p.Ile348= p.I348= ENST00000262320 NM_003502.3 348 atC/atT 0 +B3GNT2 UCSF GRCh37 2 62449935 62449935 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 136 18 207 0 ENST00000301998.4:c.580C>T p.Leu194Phe p.L194F ENST00000301998 NM_006577.5 194 Ctt/Ttt 0 +B3GNT3 UCSF GRCh37 19 17922609 17922609 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 32 251 0 ENST00000318683.6:c.797C>T p.Pro266Leu p.P266L ENST00000318683 NM_014256.3 266 cCc/cTc 0 +B4GALT2 UCSF GRCh37 1 44447495 44447495 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 264 42 332 0 ENST00000356836.6:c.448C>T p.Pro150Ser p.P150S ENST00000356836 NM_001005417.2 150 Ccc/Tcc 0 +B4GALT4 UCSF GRCh37 3 118948697 118948697 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 20 206 0 ENST00000359213.3:c.250C>T p.Leu84Phe p.L84F ENST00000359213 NM_212543.1 84 Ctc/Ttc 0 +B4GALT4 UCSF GRCh37 3 118942904 118942904 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 8 74 0 ENST00000359213.3:c.674+1G>A p.X225_splice ENST00000359213 NM_212543.1 0 +B4GALT6 UCSF GRCh37 18 29246326 29246326 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 41 356 0 ENST00000306851.5:c.125A>G p.Tyr42Cys p.Y42C ENST00000306851 NM_004775.3 42 tAt/tGt 0 +BAG5 UCSF GRCh37 14 104027253 104027253 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 25 264 0 ENST00000299204.4:c.249G>A p.Glu83= p.E83= ENST00000299204 NM_001015048.2 83 gaG/gaA 0 +BAIAP2 UCSF GRCh37 17 79089586 79089586 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 38 232 0 ENST00000321300.6:c.1552G>A p.Val518Ile p.V518I ENST00000321300 NM_001144888.1 518 Gtc/Atc 0 +BANF2 UCSF GRCh37 20 17716437 17716437 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 273 49 408 0 ENST00000246090.5:c.254G>A p.Trp85Ter p.W85* ENST00000246090 NM_178477.4 85 tGg/tAg 0 +BAZ2A UCSF GRCh37 12 56992689 56992689 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 18 144 0 ENST00000551812.1:c.5515G>A p.Asp1839Asn p.D1839N ENST00000551812 NM_013449.3 1839 Gat/Aat 0 +BBS9 UCSF GRCh37 7 33573761 33573761 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 310 43 332 0 ENST00000242067.6:c.2494G>A p.Ala832Thr p.A832T ENST00000242067 NM_198428.2 832 Gca/Aca 0 +BCHE UCSF GRCh37 3 165547469 165547469 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 372 55 471 0 ENST00000264381.3:c.1353C>T p.His451= p.H451= ENST00000264381 NM_000055.2 451 caC/caT 0 +BCKDHB UCSF GRCh37 6 80838912 80838912 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 18 131 0 ENST00000320393.6:c.309C>T p.Val103= p.V103= ENST00000320393 NM_183050.2 103 gtC/gtT 0 +BCL7A UCSF GRCh37 12 122481940 122481940 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 19 67 0 ENST00000261822.4:c.420G>A p.Lys140= p.K140= ENST00000261822 NM_001024808.1 140 aaG/aaA 0 +BCL9L UCSF GRCh37 11 118773773 118773773 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 9 66 0 ENST00000334801.3:c.760G>A p.Ala254Thr p.A254T ENST00000334801 NM_182557.2 254 Gca/Aca 0 +BDP1 UCSF GRCh37 5 70840967 70840967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 3 28 0 ENST00000358731.4:c.6665G>A p.Gly2222Asp p.G2222D ENST00000358731 NM_018429.2 2222 gGt/gAt 0 +BEND7 UCSF GRCh37 10 13481494 13481494 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 23 156 0 ENST00000341083.3:c.1085C>T p.Ala362Val p.A362V ENST00000341083 NM_152751.2 362 gCt/gTt 0 +BEST1 UCSF GRCh37 11 61730178 61730178 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 350 53 540 0 ENST00000378043.4:c.1552G>A p.Glu518Lys p.E518K ENST00000378043 NM_004183.3 518 Gag/Aag 0 +BFAR UCSF GRCh37 16 14761652 14761652 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 34 175 0 ENST00000261658.2:c.1321G>A p.Glu441Lys p.E441K ENST00000261658 NM_016561.2 441 Gaa/Aaa 0 +BFSP2 UCSF GRCh37 3 133167362 133167362 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 8 51 0 ENST00000302334.2:c.602C>T p.Ala201Val p.A201V ENST00000302334 NM_003571.2 201 gCg/gTg 0 +BHLHE23 UCSF GRCh37 20 61637563 61637563 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 10 102 0 ENST00000370346.2:c.516G>A p.Gln172= p.Q172= ENST00000370346 NM_080606.3 172 caG/caA 0 +BIRC6 UCSF GRCh37 2 32656052 32656052 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 30 276 0 ENST00000421745.2:c.3142G>A p.Glu1048Lys p.E1048K ENST00000421745 NM_016252.3 1048 Gaa/Aaa 0 +BIRC6 UCSF GRCh37 2 32836611 32836611 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 8 60 0 ENST00000421745.2:c.14356G>A p.Val4786Ile p.V4786I ENST00000421745 NM_016252.3 4786 Gta/Ata 0 +BIRC6 UCSF GRCh37 2 32695362 32695362 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 17 229 0 ENST00000421745.2:c.6474G>A p.Arg2158= p.R2158= ENST00000421745 NM_016252.3 2158 agG/agA 0 +BLM UCSF GRCh37 15 91304351 91304351 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 22 217 0 ENST00000355112.3:c.1748C>T p.Ala583Val p.A583V ENST00000355112 NM_000057.2 583 gCc/gTc 0 +BMP5 UCSF GRCh37 6 55638867 55638867 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 10 75 0 ENST00000370830.3:c.1007C>T p.Ser336Phe p.S336F ENST00000370830 NM_021073.2 336 tCc/tTc 0 +BMP7 UCSF GRCh37 20 55841041 55841041 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 29 200 0 ENST00000395863.3:c.138C>T p.Leu46= p.L46= ENST00000395863 NM_001719.2 46 ctC/ctT 0 +BMPER UCSF GRCh37 7 34125541 34125541 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 92 296 0 ENST00000297161.2:c.1582G>A p.Val528Met p.V528M ENST00000297161 NM_133468.4 528 Gtg/Atg 0 +BNIPL UCSF GRCh37 1 151010133 151010133 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 11 68 0 ENST00000368931.3:c.132C>T p.Phe44= p.F44= ENST00000368931 NM_138278.3 44 ttC/ttT 0 +BOD1L UCSF GRCh37 4 13616314 13616314 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 17 205 0 ENST00000040738.5:c.680C>T p.Ala227Val p.A227V ENST00000040738 NM_148894.2 227 gCc/gTc 0 +BOD1L UCSF GRCh37 4 13597497 13597497 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 16 222 0 ENST00000040738.5:c.8091G>A p.Lys2697= p.K2697= ENST00000040738 NM_148894.2 2697 aaG/aaA 0 +BOLL UCSF GRCh37 2 198607882 198607882 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 60 0 ENST00000392296.4:c.731C>T p.Pro244Leu p.P244L ENST00000392296 NM_033030.5 244 cCt/cTt 0 +BRAP UCSF GRCh37 12 112087772 112087772 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 14 114 0 ENST00000419234.4:c.1386C>T p.Leu462= p.L462= ENST00000419234 NM_006768.3 462 ctC/ctT 0 +BRCA2 UCSF GRCh37 13 32921010 32921010 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 9 135 0 ENST00000380152.3:c.6984G>A p.Glu2328= p.E2328= ENST00000380152 2328 gaG/gaA 0 +BRD8 UCSF GRCh37 5 137497771 137497771 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 9 109 0 ENST00000254900.5:c.2152C>T p.Leu718Phe p.L718F ENST00000254900 NM_139199.1 718 Ctt/Ttt 0 +BRDT UCSF GRCh37 1 92470740 92470740 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 13 147 0 ENST00000362005.3:c.2659G>A p.Glu887Lys p.E887K ENST00000362005 NM_001242805.1 887 Gaa/Aaa 0 +BRE UCSF GRCh37 2 28460089 28460089 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 4 51 0 ENST00000342045.2:c.701C>T p.Ala234Val p.A234V ENST00000342045 NM_199194.2 234 gCt/gTt 0 +BRF1 UCSF GRCh37 14 105766903 105766903 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 11 50 0 ENST00000546474.1:c.64G>A p.Asp22Asn p.D22N ENST00000546474 NM_001519.3 22 Gac/Aac 0 +BRIP1 UCSF GRCh37 17 59761284 59761284 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 25 267 0 ENST00000259008.2:c.3123G>A p.Met1041Ile p.M1041I ENST00000259008 NM_032043.2 1041 atG/atA 0 +BRSK1 UCSF GRCh37 19 55798397 55798397 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 15 75 1 ENST00000309383.1:c.159C>T p.His53= p.H53= ENST00000309383 NM_032430.1 53 caC/caT 0 +BRSK2 UCSF GRCh37 11 1471823 1471823 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 6 93 0 ENST00000528841.1:c.1294C>T p.Pro432Ser p.P432S ENST00000528841 432 Cct/Tct 0 +BSCL2 UCSF GRCh37 11 62457979 62457979 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 8 68 0 ENST00000403550.1:c.1057G>A p.Glu353Lys p.E353K ENST00000403550 353 Gaa/Aaa 0 +BTBD7 UCSF GRCh37 14 93727962 93727962 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 247 39 434 0 ENST00000334746.5:c.1433G>A p.Arg478Lys p.R478K ENST00000334746 NM_001002860.2 478 aGa/aAa 0 +BTN2A1 UCSF GRCh37 6 26465535 26465535 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 29 226 0 ENST00000312541.5:c.835C>T p.Leu279= p.L279= ENST00000312541 NM_007049.4 279 Ctg/Ttg 0 +BTN2A2 UCSF GRCh37 6 26384079 26384079 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 157 27 202 0 ENST00000356709.4:c.30C>T p.Ser10= p.S10= ENST00000356709 NM_001197240.1 10 tcC/tcT 0 +BTNL8 UCSF GRCh37 5 180376252 180376252 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 5 41 0 ENST00000340184.4:c.849C>T p.Ala283= p.A283= ENST00000340184 NM_001040462.2 283 gcC/gcT 0 +BTRC UCSF GRCh37 10 103310583 103310583 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 13 6 32 0 ENST00000370187.3:c.1784C>T p.Ser595Phe p.S595F ENST00000370187 NM_033637.3 595 tCc/tTc 0 +BZRAP1 UCSF GRCh37 17 56388331 56388331 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 7 96 0 ENST00000343736.4:c.3325C>T p.Pro1109Ser p.P1109S ENST00000343736 1109 Cct/Tct 0 +C10orf12 UCSF GRCh37 10 98743405 98743405 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 12 217 0 ENST00000286067.2:c.2258C>T p.Ala753Val p.A753V ENST00000286067 NM_015652.2 753 gCt/gTt 0 +C10orf12 UCSF GRCh37 10 98744660 98744660 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 4 94 0 ENST00000286067.2:c.3513G>A p.Arg1171= p.R1171= ENST00000286067 NM_015652.2 1171 agG/agA 0 +C10orf71 UCSF GRCh37 10 50534068 50534068 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 45 111 0 ENST00000374144.3:c.3478C>T p.Pro1160Ser p.P1160S ENST00000374144 1160 Cct/Tct 0 +C10orf71 UCSF GRCh37 10 50534110 50534110 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 8 99 0 ENST00000374144.3:c.3520C>T p.Pro1174Ser p.P1174S ENST00000374144 1174 Cca/Tca 0 +C10orf76 UCSF GRCh37 10 103753294 103753294 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 7 129 0 ENST00000370033.4:c.1275+1G>A p.X425_splice ENST00000370033 NM_024541.2 0 +C11orf24 UCSF GRCh37 11 68029451 68029451 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 26 186 0 ENST00000304271.6:c.1012C>T p.Pro338Ser p.P338S ENST00000304271 NM_022338.3 338 Cca/Tca 0 +C11orf35 UCSF GRCh37 11 557923 557923 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 7 33 0 ENST00000329451.3:c.516G>A p.Trp172Ter p.W172* ENST00000329451 NM_173573.2 172 tgG/tgA 0 +C12orf10 UCSF GRCh37 12 53696882 53696882 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 10 62 0 ENST00000267103.5:c.394G>A p.Ala132Thr p.A132T ENST00000267103 NM_021640.3 132 Gcg/Acg 0 +C12orf48 UCSF GRCh37 12 102542166 102542166 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 175 24 274 0 ENST00000327680.2:c.69G>A p.Met23Ile p.M23I ENST00000327680 NM_017915.3 23 atG/atA 0 +C12orf51 UCSF GRCh37 12 112623136 112623136 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 8 47 0 ENST00000550722.1:c.9196C>T p.Leu3066= p.L3066= ENST00000550722 NM_001109662.3 3066 Ctg/Ttg 0 +C12orf68 UCSF GRCh37 12 48578225 48578225 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 33 196 0 ENST00000316554.3:c.320G>A p.Gly107Asp p.G107D ENST00000316554 NM_001013635.3 107 gGc/gAc 0 +C13orf16 UCSF GRCh37 13 111995112 111995112 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 30 221 0 ENST00000283547.1:c.249G>A p.Gln83= p.Q83= ENST00000283547 NM_152324.1 83 caG/caA 0 +C14orf182 UCSF GRCh37 14 50472417 50472417 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 287 41 452 0 ENST00000399206.1:c.101C>T p.Ala34Val p.A34V ENST00000399206 NM_001012706.1 34 gCc/gTc 0 +C14orf183 UCSF GRCh37 14 50558446 50558446 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 14 165 0 ENST00000305273.1:c.122C>T p.Pro41Leu p.P41L ENST00000305273 NM_001014830.1 41 cCc/cTc 0 +C14orf37 UCSF GRCh37 14 58604864 58604864 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 25 215 0 ENST00000267485.7:c.1213G>A p.Glu405Lys p.E405K ENST00000267485 NM_001001872.2 405 Gaa/Aaa 0 +C15orf33 UCSF GRCh37 15 49907317 49907317 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 33 263 0 ENST00000299338.6:c.51+1G>A p.X17_splice ENST00000299338 NM_152647.2 0 +C15orf42 UCSF GRCh37 15 90150057 90150057 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 19 197 0 ENST00000268138.7:c.2722+1G>A p.X908_splice ENST00000268138 0 +C15orf59 UCSF GRCh37 15 74032417 74032417 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 12 144 0 ENST00000379822.4:c.723G>A p.Arg241= p.R241= ENST00000379822 NM_001039614.1 241 cgG/cgA 0 +C17orf101 UCSF GRCh37 17 80373362 80373362 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 248 53 363 0 ENST00000313056.5:c.216G>A p.Glu72= p.E72= ENST00000313056 NM_024648.2 72 gaG/gaA 0 +C17orf39 UCSF GRCh37 17 17943049 17943049 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 4 45 0 ENST00000268719.4:c.271C>T p.Pro91Ser p.P91S ENST00000268719 NM_024052.4 91 Ccc/Tcc 0 +C17orf47 UCSF GRCh37 17 56621224 56621224 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 111 400 0 ENST00000321691.3:c.324G>A p.Lys108= p.K108= ENST00000321691 NM_001038704.2 108 aaG/aaA 0 +C17orf51 UCSF GRCh37 17 21454409 21454409 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 14 95 0 ENST00000391411.5:c.277C>T p.Leu93= p.L93= ENST00000391411 NM_001113434.3 93 Ctg/Ttg 0 +C17orf53 UCSF GRCh37 17 42225701 42225701 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 9 87 0 ENST00000319977.4:c.530G>A p.Gly177Glu p.G177E ENST00000319977 NM_024032.3 177 gGa/gAa 0 +C17orf75 UCSF GRCh37 17 30662460 30662460 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 29 203 1 ENST00000577809.1:c.551C>T p.Ala184Val p.A184V ENST00000577809 NM_022344.3 184 gCa/gTa 0 +C17orf80 UCSF GRCh37 17 71232924 71232924 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 249 35 320 0 ENST00000359042.2:c.1303G>A p.Ala435Thr p.A435T ENST00000359042 NM_017941.4 435 Gcc/Acc 0 +C17orf97 UCSF GRCh37 17 263205 263205 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 30 180 0 ENST00000360127.6:c.571C>T p.Leu191= p.L191= ENST00000360127 NM_001013672.4 191 Ctg/Ttg 0 +C18orf8 UCSF GRCh37 18 21098917 21098917 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 13 44 0 ENST00000269221.3:c.717G>A p.Ala239= p.A239= ENST00000269221 NM_013326.4 239 gcG/gcA 0 +C19orf29 UCSF GRCh37 19 3623943 3623943 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 193 70 208 0 ENST00000221899.3:c.181G>A p.Ala61Thr p.A61T ENST00000221899 61 Gcg/Acg 0 +C19orf29 UCSF GRCh37 19 3623985 3623985 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 12 112 0 ENST00000221899.3:c.139G>A p.Ala47Thr p.A47T ENST00000221899 47 Gca/Aca 0 +C19orf29 UCSF GRCh37 19 3613530 3613530 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 136 17 145 0 ENST00000221899.3:c.1206G>A p.Gln402= p.Q402= ENST00000221899 402 caG/caA 0 +C1orf106 UCSF GRCh37 1 200876961 200876961 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 4 23 0 ENST00000367342.4:c.776-1G>A p.X259_splice ENST00000367342 NM_018265.3 0 +C1orf127 UCSF GRCh37 1 11007896 11007896 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 12 101 0 ENST00000377004.4:c.2296C>T p.Pro766Ser p.P766S ENST00000377004 NM_001170754.1 766 Ccc/Tcc 0 +C1orf141 UCSF GRCh37 1 67592920 67592920 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 328 54 571 1 ENST00000371006.1:c.4G>A p.Ala2Thr p.A2T ENST00000371006 2 Gca/Aca 0 +C1orf173 UCSF GRCh37 1 75055443 75055443 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 32 299 0 ENST00000326665.5:c.2048G>A p.Gly683Asp p.G683D ENST00000326665 NM_001002912.4 683 gGt/gAt 0 +C1orf63 UCSF GRCh37 1 25573350 25573350 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 26 190 0 ENST00000243189.7:c.105G>A p.Arg35= p.R35= ENST00000243189 NM_020317.3 35 agG/agA 0 +C1orf65 UCSF GRCh37 1 223568113 223568113 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 4 17 0 ENST00000366875.3:c.1296C>T p.Ala432= p.A432= ENST00000366875 NM_152610.2 432 gcC/gcT 0 +C1S UCSF GRCh37 12 7173913 7173913 + synonymous_variant Silent SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 23 126 0 ENST00000328916.3:c.963T>C p.Cys321= p.C321= ENST00000328916 NM_201442.2 321 tgT/tgC 0 +C2 UCSF GRCh37 6 31905227 31905227 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 5 35 0 ENST00000299367.5:c.1120C>T p.Leu374= p.L374= ENST00000299367 NM_000063.4 374 Ctg/Ttg 0 +C20orf132 UCSF GRCh37 20 35788532 35788532 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 284 46 412 0 ENST00000343811.4:c.776C>T p.Arg259= p.R259= ENST00000343811 NM_152503.4 259 cgC/cgT 0 +C20orf177 UCSF GRCh37 20 58519916 58519916 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 13 160 0 ENST00000358293.3:c.918G>A p.Trp306Ter p.W306* ENST00000358293 NM_001190826.1 306 tgG/tgA 0 +C20orf3 UCSF GRCh37 20 24950902 24950902 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 32 251 0 ENST00000217456.2:c.644C>T p.Thr215Ile p.T215I ENST00000217456 NM_020531.2 215 aCc/aTc 0 +C22orf29 UCSF GRCh37 22 19839202 19839202 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 22 241 0 ENST00000328554.4:c.583C>T p.Pro195Ser p.P195S ENST00000328554 NM_024627.5 195 Ccc/Tcc 0 +C2orf15 UCSF GRCh37 2 99766983 99766983 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 19 180 0 ENST00000302513.2:c.64G>A p.Val22Ile p.V22I ENST00000302513 NM_144706.2 22 Gta/Ata 0 +C2orf16 UCSF GRCh37 2 27802966 27802966 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 217 28 342 1 ENST00000408964.2:c.3527C>T p.Ser1176Phe p.S1176F ENST00000408964 NM_032266.3 1176 tCc/tTc 0 +C2orf16 UCSF GRCh37 2 27802761 27802761 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 379 67 584 0 ENST00000408964.2:c.3322C>T p.Pro1108Ser p.P1108S ENST00000408964 NM_032266.3 1108 Cca/Tca 0 +C2orf28 UCSF GRCh37 2 27439390 27439390 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 16 154 0 ENST00000606999.1:c.488-1G>A p.X163_splice ENST00000606999 NM_001170795.1 0 +C2orf29 UCSF GRCh37 2 101869740 101869740 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 11 143 0 ENST00000289382.3:c.314G>A p.Gly105Asp p.G105D ENST00000289382 NM_017546.4 105 gGc/gAc 0 +C2orf65 UCSF GRCh37 2 74785967 74785967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 285 52 380 0 ENST00000290536.5:c.1469C>T p.Thr490Ile p.T490I ENST00000290536 NM_138804.4 490 aCt/aTt 0 +C3orf17 UCSF GRCh37 3 112730247 112730247 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 37 256 0 ENST00000314400.5:c.558C>T p.Leu186= p.L186= ENST00000314400 NM_015412.3 186 ctC/ctT 0 +C3orf25 UCSF GRCh37 3 129120583 129120583 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 28 0 ENST00000326085.3:c.1572C>T p.Asp524= p.D524= ENST00000326085 524 gaC/gaT 0 +C3orf58 UCSF GRCh37 3 143708377 143708377 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 17 185 0 ENST00000315691.3:c.987G>A p.Trp329Ter p.W329* ENST00000315691 NM_173552.3 329 tgG/tgA 0 +C3orf77 UCSF GRCh37 3 44310793 44310793 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 14 115 0 ENST00000309765.4:c.3246G>A p.Gly1082= p.G1082= ENST00000309765 NM_001145030.1 1082 ggG/ggA 0 +C4BPB UCSF GRCh37 1 207271536 207271536 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 21 202 0 ENST00000243611.5:c.545G>A p.Gly182Glu p.G182E ENST00000243611 NM_000716.3 182 gGg/gAg 0 +C4orf14 UCSF GRCh37 4 57843376 57843376 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 39 219 0 ENST00000264230.4:c.376G>A p.Val126Ile p.V126I ENST00000264230 NM_032313.2 126 Gtc/Atc 0 +C4orf17 UCSF GRCh37 4 100443827 100443827 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 10 42 0 ENST00000326581.4:c.298G>A p.Ala100Thr p.A100T ENST00000326581 NM_032149.2 100 Gcc/Acc 0 +C4orf21 UCSF GRCh37 4 113538832 113538832 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 342 48 507 0 ENST00000445203.2:c.2273G>A p.Gly758Glu p.G758E ENST00000445203 758 gGa/gAa 0 +C5orf34 UCSF GRCh37 5 43503809 43503809 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 228 26 317 0 ENST00000306862.2:c.986C>T p.Pro329Leu p.P329L ENST00000306862 NM_198566.2 329 cCt/cTt 0 +C5orf35 UCSF GRCh37 5 56205488 56205488 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 18 144 0 ENST00000285947.2:c.16C>T p.Leu6= p.L6= ENST00000285947 NM_153706.3 6 Ctg/Ttg 0 +C5orf42 UCSF GRCh37 5 37244646 37244646 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 58 220 0 ENST00000425232.2:c.401C>T p.Pro134Leu p.P134L ENST00000425232 NM_023073.3 134 cCt/cTt 0 +C5orf54 UCSF GRCh37 5 159820941 159820941 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 293 47 412 0 ENST00000408953.3:c.1557C>T p.Ala519= p.A519= ENST00000408953 NM_022090.3 519 gcC/gcT 0 +C6orf106 UCSF GRCh37 6 34664256 34664256 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 77 1 ENST00000374023.3:c.125C>T p.Ala42Val p.A42V ENST00000374023 NM_024294.2 42 gCc/gTc 0 +C6orf203 UCSF GRCh37 6 107372309 107372309 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 7 59 0 ENST00000311381.5:c.592G>A p.Ala198Thr p.A198T ENST00000311381 NM_016487.3 198 Gca/Aca 0 +C6orf25 UCSF GRCh37 6 31691969 31691969 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 39 296 0 ENST00000375806.2:c.460C>T p.Leu154Phe p.L154F ENST00000375806 154 Ctc/Ttc 0 +C6orf27 UCSF GRCh37 6 31737510 31737510 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 14 51 0 ENST00000375688.4:c.1259C>T p.Pro420Leu p.P420L ENST00000375688 420 cCc/cTc 0 +C7orf36 UCSF GRCh37 7 39612265 39612265 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 16 195 0 ENST00000223273.2:c.641G>A p.Gly214Asp p.G214D ENST00000223273 NM_020192.3 214 gGc/gAc 0 +C7orf47 UCSF GRCh37 7 100032988 100032988 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 11 93 0 ENST00000292330.2:c.757G>A p.Ala253Thr p.A253T ENST00000292330 NM_145030.2 253 Gcg/Acg 0 +C7orf70 UCSF GRCh37 7 6370050 6370050 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 18 117 0 ENST00000313324.4:c.736G>A p.Ala246Thr p.A246T ENST00000313324 NM_001037163.1 246 Gct/Act 0 +C9orf139 UCSF GRCh37 9 139929283 139929283 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 199 34 237 0 ENST00000314330.2:c.350C>T p.Pro117Leu p.P117L ENST00000314330 NM_207511.1 117 cCc/cTc 0 +C9orf140 UCSF GRCh37 9 139960809 139960809 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 15 123 0 ENST00000409687.3:c.589G>A p.Ala197Thr p.A197T ENST00000409687 NM_178448.3 197 Gcc/Acc 0 +C9orf156 UCSF GRCh37 9 100672771 100672771 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 13 136 0 ENST00000375119.3:c.537G>A p.Gln179= p.Q179= ENST00000375119 NM_016481.3 179 caG/caA 0 +C9orf169 UCSF GRCh37 9 140120399 140120399 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 11 138 0 ENST00000359069.2:c.326G>A p.Gly109Glu p.G109E ENST00000359069 NM_199001.2 109 gGg/gAg 0 +C9orf47 UCSF GRCh37 9 91606069 91606069 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 15 127 0 ENST00000334490.5:c.159C>T p.Phe53= p.F53= ENST00000334490 53 ttC/ttT 0 +C9orf68 UCSF GRCh37 9 4622455 4622455 + missense_variant,NMD_transcript_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 14 88 0 ENST00000461761.1:c.725C>T p.Ser242Phe p.S242F ENST00000461761 242 tCt/tTt 0 +C9orf86 UCSF GRCh37 9 139731824 139731824 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 3 25 0 ENST00000311502.7:c.836G>A p.Ser279Asn p.S279N ENST00000311502 279 aGc/aAc 0 +CABIN1 UCSF GRCh37 22 24456476 24456476 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 144 28 195 0 ENST00000263119.5:c.1489C>T p.His497Tyr p.H497Y ENST00000263119 NM_012295.3 497 Cac/Tac 0 +CACHD1 UCSF GRCh37 1 65117844 65117844 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 19 149 0 ENST00000290039.5:c.1238G>A p.Gly413Asp p.G413D ENST00000290039 NM_020925.2 413 gGt/gAt 0 +CACNA1A UCSF GRCh37 19 13340982 13340982 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 14 99 0 ENST00000360228.5:c.5442G>A p.Glu1814= p.E1814= ENST00000360228 NM_001127222.1 1814 gaG/gaA 0 +CACNA1E UCSF GRCh37 1 181701955 181701955 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 8 84 0 ENST00000367573.2:c.2733G>A p.Arg911= p.R911= ENST00000367573 NM_001205293.1 911 cgG/cgA 0 +CACNA1F UCSF GRCh37 X 49063214 49063214 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 78 0 ENST00000376265.2:c.5367C>T p.Arg1789= p.R1789= ENST00000376265 NM_005183.2 1789 cgC/cgT 0 +CACNA2D2 UCSF GRCh37 3 50425020 50425020 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 7 63 1 ENST00000479441.1:c.489C>T p.Asp163= p.D163= ENST00000479441 163 gaC/gaT 0 +CACNA2D4 UCSF GRCh37 12 1969357 1969357 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 29 234 0 ENST00000382722.5:c.1894C>T p.Leu632= p.L632= ENST00000382722 NM_172364.4 632 Ctg/Ttg 0 +CACNB4 UCSF GRCh37 2 152698533 152698533 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 212 38 307 0 ENST00000539935.1:c.1186G>A p.Glu396Lys p.E396K ENST00000539935 NM_001145798.1 396 Gag/Aag 0 +CAD UCSF GRCh37 2 27448004 27448004 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 85 191 0 ENST00000264705.4:c.1513C>T p.Pro505Ser p.P505S ENST00000264705 NM_004341.3 505 Cca/Tca 0 +CALCR UCSF GRCh37 7 93067438 93067438 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 11 112 0 ENST00000359558.2:c.966C>T p.Asn322= p.N322= ENST00000359558 NM_001164737.1 322 aaC/aaT 0 +CALCRL UCSF GRCh37 2 188217005 188217005 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 23 228 0 ENST00000392370.3:c.964G>A p.Val322Ile p.V322I ENST00000392370 NM_005795.5 322 Gtt/Att 0 +CALD1 UCSF GRCh37 7 134625943 134625943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 26 97 0 ENST00000361675.2:c.1487G>A p.Gly496Glu p.G496E ENST00000361675 496 gGa/gAa 0 +CALR3 UCSF GRCh37 19 16596053 16596053 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 31 233 0 ENST00000269881.3:c.413G>A p.Gly138Glu p.G138E ENST00000269881 NM_145046.4 138 gGa/gAa 0 +CAMKK1 UCSF GRCh37 17 3785649 3785649 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 26 160 0 ENST00000348335.2:c.685+173C>T *229* ENST00000348335 NM_032294.2 0 +CAND2 UCSF GRCh37 3 12854500 12854500 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 8 85 0 ENST00000456430.2:c.769G>A p.Asp257Asn p.D257N ENST00000456430 NM_001162499.1 257 Gac/Aac 0 +CAPG UCSF GRCh37 2 85628372 85628372 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 15 172 0 ENST00000263867.4:c.432G>A p.Gly144= p.G144= ENST00000263867 NM_001256140.1 144 ggG/ggA 0 +CAPN1 UCSF GRCh37 11 64951005 64951005 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 22 131 0 ENST00000279247.6:c.398G>A p.Arg133Gln p.R133Q ENST00000279247 NM_005186.3 133 cGa/cAa 0 +CARD10 UCSF GRCh37 22 37902215 37902215 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 18 0 ENST00000251973.5:c.1367G>A p.Gly456Asp p.G456D ENST00000251973 NM_014550.3 456 gGt/gAt 0 +CARD10 UCSF GRCh37 22 37903890 37903890 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 18 115 0 ENST00000251973.5:c.1137C>T p.His379= p.H379= ENST00000251973 NM_014550.3 379 caC/caT 0 +CARD14 UCSF GRCh37 17 78165266 78165266 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 52 0 ENST00000344227.2:c.1234G>A p.Gly412Ser p.G412S ENST00000344227 NM_024110.4 412 Ggt/Agt 0 +CARD14 UCSF GRCh37 17 78166319 78166319 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 6 46 0 ENST00000344227.2:c.1257G>A p.Arg419= p.R419= ENST00000344227 NM_024110.4 419 agG/agA 0 +CARD8 UCSF GRCh37 19 48733713 48733713 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 25 239 0 ENST00000391898.3:c.1017C>T p.Ser339= p.S339= ENST00000391898 NM_001184900.1 339 agC/agT 0 +CARD8 UCSF GRCh37 19 48734242 48734242 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 4 63 0 ENST00000391898.3:c.564C>T p.Gly188= p.G188= ENST00000391898 NM_001184900.1 188 ggC/ggT 0 +CARM1 UCSF GRCh37 19 11022892 11022892 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 401 151 508 0 ENST00000327064.4:c.591C>T p.Ile197= p.I197= ENST00000327064 NM_199141.1 197 atC/atT 0 +CARS UCSF GRCh37 11 3028116 3028116 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 16 193 0 ENST00000397111.5:c.1893C>T p.Asp631= p.D631= ENST00000397111 631 gaC/gaT 0 +CASKIN1 UCSF GRCh37 16 2230836 2230836 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 51 0 ENST00000343516.6:c.2533G>A p.Gly845Arg p.G845R ENST00000343516 NM_020764.3 845 Ggg/Agg 0 +CASKIN2 UCSF GRCh37 17 73498124 73498124 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 17 111 0 ENST00000321617.3:c.3031G>A p.Val1011Met p.V1011M ENST00000321617 NM_020753.4 1011 Gtg/Atg 0 +CASKIN2 UCSF GRCh37 17 73509868 73509868 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 214 47 296 0 ENST00000321617.3:c.18C>T p.Asp6= p.D6= ENST00000321617 NM_020753.4 6 gaC/gaT 0 +CASP1 UCSF GRCh37 11 104897673 104897673 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 20 165 0 ENST00000436863.3:c.1012G>A p.Val338Ile p.V338I ENST00000436863 NM_033292.3 338 Gtt/Att 0 +CASP8AP2 UCSF GRCh37 6 90562942 90562942 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 33 241 0 ENST00000551025.1:n.1550G>A *517* ENST00000551025 0 +CBFA2T2 UCSF GRCh37 20 32212628 32212628 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 41 305 0 ENST00000346541.3:c.778G>A p.Val260Ile p.V260I ENST00000346541 NM_005093.3 260 Gta/Ata 0 +CBL UCSF GRCh37 11 119145623 119145623 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 12 104 0 ENST00000264033.4:c.829G>A p.Val277Met p.V277M ENST00000264033 NM_005188.3 277 Gtg/Atg 0 +CBX2 UCSF GRCh37 17 77758206 77758206 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 18 141 0 ENST00000310942.4:c.964G>A p.Gly322Arg p.G322R ENST00000310942 NM_005189.2 322 Ggg/Agg 0 +CBX6 UCSF GRCh37 22 39262663 39262663 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 13 59 0 ENST00000407418.3:c.790C>T p.Pro264Ser p.P264S ENST00000407418 264 Ccc/Tcc 0 +CCBE1 UCSF GRCh37 18 57107014 57107014 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 6 37 0 ENST00000439986.4:c.810C>T p.Pro270= p.P270= ENST00000439986 NM_133459.3 270 ccC/ccT 0 +CCDC108 UCSF GRCh37 2 219903674 219903674 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 9 70 0 ENST00000341552.5:c.97C>T p.Leu33Phe p.L33F ENST00000341552 NM_194302.3 33 Ctc/Ttc 0 +CCDC112 UCSF GRCh37 5 114612683 114612683 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 9 80 0 ENST00000395557.4:c.181G>A p.Asp61Asn p.D61N ENST00000395557 NM_152549.2 61 Gat/Aat 0 +CCDC113 UCSF GRCh37 16 58312424 58312424 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 7 36 0 ENST00000219299.4:c.930G>A p.Arg310= p.R310= ENST00000219299 NM_014157.3 310 cgG/cgA 0 +CCDC13 UCSF GRCh37 3 42798628 42798628 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 263 35 374 0 ENST00000310232.6:c.300G>A p.Leu100= p.L100= ENST00000310232 NM_144719.3 100 ctG/ctA 0 +CCDC157 UCSF GRCh37 22 30771592 30771592 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 21 115 0 ENST00000338306.3:c.1797C>T p.Asn599= p.N599= ENST00000338306 NM_001017437.2 599 aaC/aaT 0 +CCDC158 UCSF GRCh37 4 77288491 77288491 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 12 141 0 ENST00000388914.3:c.1786G>A p.Glu596Lys p.E596K ENST00000388914 NM_001042784.1 596 Gag/Aag 0 +CCDC169 UCSF GRCh37 13 36869981 36869981 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 30 282 0 ENST00000239859.7:c.97C>T p.Leu33Phe p.L33F ENST00000239859 33 Ctc/Ttc 0 +CCDC28A UCSF GRCh37 6 139100982 139100982 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 7 55 0 ENST00000332797.6:c.452C>T p.Pro151Leu p.P151L ENST00000332797 NM_015439.2 151 cCt/cTt 0 +CCDC42B UCSF GRCh37 12 113592333 113592333 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 3 19 0 ENST00000335621.6:c.583C>T p.Leu195= p.L195= ENST00000335621 NM_001144872.1 195 Ctg/Ttg 0 +CCDC48 UCSF GRCh37 3 128758672 128758672 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 337 38 446 0 ENST00000436022.2:c.467C>T p.Pro156Leu p.P156L ENST00000436022 NM_024768.2 156 cCc/cTc 0 +CCDC67 UCSF GRCh37 11 93127823 93127823 + splice_donor_variant Splice_Site SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 4 34 0 ENST00000298050.3:c.1239+1G>T p.X413_splice ENST00000298050 NM_181645.3 0 +CCDC70 UCSF GRCh37 13 52440126 52440126 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 11 140 0 ENST00000242819.4:c.612C>T p.Gly204= p.G204= ENST00000242819 NM_031290.2 204 ggC/ggT 0 +CCDC80 UCSF GRCh37 3 112358176 112358176 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 29 203 0 ENST00000206423.3:c.577G>A p.Ala193Thr p.A193T ENST00000206423 NM_199512.1 193 Gca/Aca 0 +CCDC87 UCSF GRCh37 11 66360341 66360341 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 43 133 0 ENST00000333861.3:c.146C>T p.Pro49Leu p.P49L ENST00000333861 NM_018219.2 49 cCt/cTt 0 +CCDC88B UCSF GRCh37 11 64117117 64117117 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 6 42 0 ENST00000356786.5:c.2839C>T p.Gln947Ter p.Q947* ENST00000356786 NM_032251.5 947 Cag/Tag 0 +CCDC88B UCSF GRCh37 11 64111020 64111020 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 43 296 0 ENST00000356786.5:c.1251G>A p.Glu417= p.E417= ENST00000356786 NM_032251.5 417 gaG/gaA 0 +CCDC96 UCSF GRCh37 4 7044063 7044063 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 708 115 847 1 ENST00000310085.4:c.603C>T p.Leu201= p.L201= ENST00000310085 NM_153376.2 201 ctC/ctT 0 +CCKBR UCSF GRCh37 11 6281250 6281250 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 5 57 0 ENST00000334619.2:c.92G>A p.Ser31Asn p.S31N ENST00000334619 NM_176875.3 31 aGc/aAc 0 +CCNE1 UCSF GRCh37 19 30313252 30313252 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 27 276 0 ENST00000262643.3:c.946G>A p.Val316Ile p.V316I ENST00000262643 NM_001238.2 316 Gtt/Att 0 +CCPG1 UCSF GRCh37 15 55669234 55669234 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 46 154 0 ENST00000310958.6:c.367G>A p.Val123Ile p.V123I ENST00000310958 NM_001204451.1 123 Gtc/Atc 0 +CCPG1 UCSF GRCh37 15 55652252 55652252 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 233 31 398 0 ENST00000310958.6:c.1719G>A p.Gln573= p.Q573= ENST00000310958 NM_001204451.1 573 caG/caA 0 +CCR4 UCSF GRCh37 3 32994996 32994996 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 22 196 0 ENST00000330953.5:c.82C>T p.Pro28Ser p.P28S ENST00000330953 NM_005508.4 28 Cct/Tct 0 +CCT7 UCSF GRCh37 2 73470250 73470250 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 404 73 563 0 ENST00000258091.5:c.386C>T p.Thr129Ile p.T129I ENST00000258091 NM_006429.3 129 aCc/aTc 0 +CCT7 UCSF GRCh37 2 73471671 73471671 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 13 132 0 ENST00000258091.5:c.447-1G>A p.X149_splice ENST00000258091 NM_006429.3 0 +CD101 UCSF GRCh37 1 117559842 117559842 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 10 67 0 ENST00000256652.4:c.1359C>T p.Asp453= p.D453= ENST00000256652 NM_004258.5 453 gaC/gaT 0 +CD19 UCSF GRCh37 16 28946795 28946795 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 26 239 0 ENST00000324662.3:c.866G>A p.Gly289Asp p.G289D ENST00000324662 289 gGc/gAc 0 +CD1E UCSF GRCh37 1 158325748 158325748 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 4 57 0 ENST00000368167.3:c.757G>A p.Gly253Ser p.G253S ENST00000368167 NM_030893.3 253 Ggc/Agc 0 +CD22 UCSF GRCh37 19 35837562 35837562 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 17 195 0 ENST00000085219.5:c.2506G>A p.Ala836Thr p.A836T ENST00000085219 NM_001771.3 836 Gca/Aca 0 +CD248 UCSF GRCh37 11 66084293 66084293 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 5 38 1 ENST00000311330.3:c.206G>A p.Arg69His p.R69H ENST00000311330 NM_020404.2 69 cGt/cAt 0 +CD300LB UCSF GRCh37 17 72522017 72522017 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 369 47 545 0 ENST00000392621.1:c.351C>T p.Asp117= p.D117= ENST00000392621 NM_174892.3 117 gaC/gaT 0 +CD300LG UCSF GRCh37 17 41932684 41932684 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 30 248 0 ENST00000317310.4:c.829G>A p.Glu277Lys p.E277K ENST00000317310 NM_145273.3 277 Gaa/Aaa 0 +CD79B UCSF GRCh37 17 62009612 62009612 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 39 0 ENST00000006750.3:c.10C>T p.Leu4= p.L4= ENST00000006750 NM_021602.2 4 Ctg/Ttg 0 +CD82 UCSF GRCh37 11 44640662 44640662 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 72 468 0 ENST00000227155.4:c.790G>A p.Val264Ile p.V264I ENST00000227155 NM_002231.3 264 Gtc/Atc 0 +CD86 UCSF GRCh37 3 121838324 121838324 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 14 74 0 ENST00000330540.2:c.933G>A p.Gln311= p.Q311= ENST00000330540 NM_175862.4 311 caG/caA 0 +CDADC1 UCSF GRCh37 13 49822220 49822220 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 5 24 0 ENST00000251108.6:c.47G>A p.Gly16Glu p.G16E ENST00000251108 NM_001193478.1 16 gGg/gAg 0 +CDAN1 UCSF GRCh37 15 43017755 43017755 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 17 112 0 ENST00000356231.3:c.3382C>T p.Pro1128Ser p.P1128S ENST00000356231 NM_138477.2 1128 Ccg/Tcg 0 +CDAN1 UCSF GRCh37 15 43028098 43028098 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 37 232 0 ENST00000356231.3:c.748G>A p.Glu250Lys p.E250K ENST00000356231 NM_138477.2 250 Gag/Aag 0 +CDC14A UCSF GRCh37 1 100889822 100889822 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 351 58 561 0 ENST00000336454.3:c.354C>T p.Leu118= p.L118= ENST00000336454 NM_003672.3 118 ctC/ctT 0 +CDC42BPA UCSF GRCh37 1 227219128 227219128 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 255 43 401 0 ENST00000334218.5:c.3541G>A p.Gly1181Arg p.G1181R ENST00000334218 1181 Gga/Aga 0 +CDC42BPA UCSF GRCh37 1 227300117 227300117 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 22 235 0 ENST00000334218.5:c.1897G>A p.Val633Ile p.V633I ENST00000334218 633 Gtt/Att 0 +CDC42EP4 UCSF GRCh37 17 71281979 71281979 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 29 226 0 ENST00000335793.3:c.661G>A p.Val221Ile p.V221I ENST00000335793 221 Gtc/Atc 0 +CDC5L UCSF GRCh37 6 44360425 44360425 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 8 45 0 ENST00000371477.3:c.171C>T p.Ser57= p.S57= ENST00000371477 NM_001253.3 57 agC/agT 0 +CDC6 UCSF GRCh37 17 38447468 38447468 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 93 354 0 ENST00000209728.4:c.337G>A p.Ala113Thr p.A113T ENST00000209728 NM_001254.3 113 Gcc/Acc 0 +CDCA7L UCSF GRCh37 7 21947778 21947778 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 6 35 0 ENST00000406877.3:c.651G>A p.Arg217= p.R217= ENST00000406877 NM_018719.4 217 agG/agA 0 +CDH11 UCSF GRCh37 16 64984895 64984895 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 84 0 ENST00000268603.4:c.1669C>T p.Arg557Cys p.R557C ENST00000268603 NM_001797.2 557 Cgt/Tgt 0 +CDH23 UCSF GRCh37 10 73437447 73437447 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 7 8 35 0 ENST00000224721.6:c.1764C>T p.Leu588= p.L588= ENST00000224721 NM_022124.5 588 ctC/ctT 0 +CDH6 UCSF GRCh37 5 31302331 31302331 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 10 93 0 ENST00000265071.2:c.925G>A p.Asp309Asn p.D309N ENST00000265071 NM_004932.3 309 Gac/Aac 0 +CDH7 UCSF GRCh37 18 63477089 63477089 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 8 103 0 ENST00000323011.3:c.360C>T p.Leu120= p.L120= ENST00000323011 NM_033646.1 120 ctC/ctT 0 +CDHR5 UCSF GRCh37 11 618993 618993 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 11 61 0 ENST00000358353.3:c.1566G>A p.Pro522= p.P522= ENST00000358353 522 ccG/ccA 0 +CDK19 UCSF GRCh37 6 110953334 110953334 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 27 359 0 ENST00000368911.3:c.545C>T p.Ser182Phe p.S182F ENST00000368911 NM_015076.3 182 tCt/tTt 0 +CDK6 UCSF GRCh37 7 92247402 92247402 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 78 11 106 0 ENST00000265734.4:c.818G>A p.Gly273Asp p.G273D ENST00000265734 NM_001259.6 273 gGc/gAc 0 +CDKL3 UCSF GRCh37 5 133695755 133695755 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 7 42 0 ENST00000265334.4:c.193C>T p.Leu65= p.L65= ENST00000265334 NM_001113575.1 65 Ctg/Ttg 0 +CDKL4 UCSF GRCh37 2 39456661 39456661 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 47 439 0 ENST00000395035.3:c.13G>A p.Glu5Lys p.E5K ENST00000395035 5 Gaa/Aaa 0 +CDS2 UCSF GRCh37 20 5157294 5157294 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 19 163 0 ENST00000460006.1:c.292G>A p.Val98Met p.V98M ENST00000460006 NM_003818.3 98 Gtg/Atg 0 +CDX2 UCSF GRCh37 13 28542701 28542701 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 11 82 0 ENST00000381020.7:c.443C>T p.Ala148Val p.A148V ENST00000381020 NM_001265.4 148 gCc/gTc 0 +CECR2 UCSF GRCh37 22 18021882 18021882 + downstream_gene_variant 3'Flank SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 57 0 ENST00000342247 0 +CELF6 UCSF GRCh37 15 72581778 72581778 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 21 112 0 ENST00000287202.5:c.818C>T p.Ala273Val p.A273V ENST00000287202 NM_052840.4 273 gCg/gTg 0 +CELSR2 UCSF GRCh37 1 109801126 109801126 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 13 107 0 ENST00000271332.3:c.3383G>A p.Ser1128Asn p.S1128N ENST00000271332 NM_001408.2 1128 aGc/aAc 0 +CELSR2 UCSF GRCh37 1 109806880 109806880 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 16 162 0 ENST00000271332.3:c.5182G>A p.Gly1728Ser p.G1728S ENST00000271332 NM_001408.2 1728 Ggc/Agc 0 +CELSR3 UCSF GRCh37 3 48698042 48698042 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 272 45 368 1 ENST00000164024.4:c.2026G>A p.Val676Ile p.V676I ENST00000164024 NM_001407.2 676 Gtc/Atc 0 +CELSR3 UCSF GRCh37 3 48681069 48681069 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 8 30 0 ENST00000164024.4:c.8207C>T p.Ala2736Val p.A2736V ENST00000164024 NM_001407.2 2736 gCc/gTc 0 +CENPB UCSF GRCh37 20 3766314 3766314 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 15 156 0 ENST00000379751.4:c.817G>A p.Ala273Thr p.A273T ENST00000379751 NM_001810.5 273 Gcc/Acc 0 +CENPO UCSF GRCh37 2 25016798 25016798 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 19 136 0 ENST00000260662.1:c.10G>A p.Ala4Thr p.A4T ENST00000260662 NM_024322.2 4 Gcg/Acg 0 +CEP112 UCSF GRCh37 17 64128857 64128857 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 15 136 0 ENST00000392769.2:c.495C>T p.Leu165= p.L165= ENST00000392769 NM_145036.3 165 ctC/ctT 0 +CEP135 UCSF GRCh37 4 56846433 56846433 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 25 96 0 ENST00000257287.4:c.1598G>A p.Arg533Lys p.R533K ENST00000257287 NM_025009.4 533 aGa/aAa 0 +CEP250 UCSF GRCh37 20 34092083 34092083 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 7 74 0 ENST00000397527.1:c.5886G>A p.Arg1962= p.R1962= ENST00000397527 NM_007186.3 1962 cgG/cgA 0 +CEP350 UCSF GRCh37 1 180059928 180059928 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 22 333 0 ENST00000367607.3:c.6505G>A p.Val2169Ile p.V2169I ENST00000367607 NM_014810.4 2169 Gtt/Att 0 +CEP85 UCSF GRCh37 1 26597537 26597537 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 23 159 1 ENST00000252992.4:c.1682G>A p.Ser561Asn p.S561N ENST00000252992 NM_022778.3 561 aGt/aAt 0 +CEP97 UCSF GRCh37 3 101450725 101450725 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 22 226 0 ENST00000341893.3:c.489G>A p.Met163Ile p.M163I ENST00000341893 163 atG/atA 0 +CFTR UCSF GRCh37 7 117232451 117232451 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 378 47 394 0 ENST00000003084.6:c.2230C>T p.Gln744Ter p.Q744* ENST00000003084 NM_000492.3 744 Cag/Tag 0 +CHD2 UCSF GRCh37 15 93540211 93540211 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 7 97 0 ENST00000394196.4:c.3620G>A p.Gly1207Asp p.G1207D ENST00000394196 NM_001271.3 1207 gGt/gAt 0 +CHD3 UCSF GRCh37 17 7806808 7806808 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 511 95 708 0 ENST00000330494.7:c.3714G>A p.Lys1238= p.K1238= ENST00000330494 NM_001005273.2 1238 aaG/aaA 0 +CHD8 UCSF GRCh37 14 21876526 21876526 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 12 147 0 ENST00000399982.2:c.2675G>A p.Ser892Asn p.S892N ENST00000399982 NM_001170629.1 892 aGt/aAt 0 +CHD9 UCSF GRCh37 16 53355489 53355489 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 10 134 0 ENST00000398510.3:c.7765G>A p.Glu2589Lys p.E2589K ENST00000398510 2589 Gaa/Aaa 0 +CHD9 UCSF GRCh37 16 53190970 53190970 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 44 387 0 ENST00000398510.3:c.969G>A p.Gln323= p.Q323= ENST00000398510 323 caG/caA 0 +CHFR UCSF GRCh37 12 133454233 133454233 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 8 118 0 ENST00000432561.2:c.141C>T p.Asp47= p.D47= ENST00000432561 47 gaC/gaT 0 +CHPF UCSF GRCh37 2 220404996 220404996 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 60 384 0 ENST00000243776.6:c.1437G>A p.Arg479= p.R479= ENST00000243776 NM_024536.5 479 cgG/cgA 0 +CHPF2 UCSF GRCh37 7 150934836 150934836 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 23 112 0 ENST00000035307.2:c.1388C>T p.Ala463Val p.A463V ENST00000035307 NM_019015.1 463 gCt/gTt 0 +CHRM4 UCSF GRCh37 11 46408064 46408064 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 224 32 293 0 ENST00000433765.2:c.44C>T p.Ser15Phe p.S15F ENST00000433765 NM_000741.2 15 tCc/tTc 0 +CHRNB2 UCSF GRCh37 1 154543944 154543944 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 298 39 370 0 ENST00000368476.3:c.645C>T p.Asn215= p.N215= ENST00000368476 NM_000748.2 215 aaC/aaT 0 +CHRNB2 UCSF GRCh37 1 154544313 154544313 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 31 310 0 ENST00000368476.3:c.1014C>T p.Val338= p.V338= ENST00000368476 NM_000748.2 338 gtC/gtT 0 +CHST12 UCSF GRCh37 7 2473490 2473490 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 39 415 0 ENST00000258711.6:c.1216C>T p.Pro406Ser p.P406S ENST00000258711 NM_001243794.1 406 Ccc/Tcc 0 +CHSY3 UCSF GRCh37 5 129240784 129240784 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 33 0 ENST00000305031.4:c.262C>T p.Leu88= p.L88= ENST00000305031 NM_175856.4 88 Ctg/Ttg 0 +CHUK UCSF GRCh37 10 101964296 101964296 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 48 386 0 ENST00000370397.7:c.1474G>A p.Glu492Lys p.E492K ENST00000370397 NM_001278.3 492 Gag/Aag 0 +CHURC1-FNTB UCSF GRCh37 14 65520017 65520017 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 16 141 0 ENST00000246166.2:c.1017C>T p.Ile339= p.I339= ENST00000246166 NM_002028.3 339 atC/atT 0 +CILP UCSF GRCh37 15 65490810 65490810 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 19 176 0 ENST00000261883.4:c.1814C>T p.Ser605Phe p.S605F ENST00000261883 NM_003613.3 605 tCc/tTc 0 +CITED2 UCSF GRCh37 6 139694288 139694288 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 495 89 625 0 ENST00000367651.2:c.794C>T p.Pro265Leu p.P265L ENST00000367651 NM_006079.4 265 cCc/cTc 0 +CKAP2L UCSF GRCh37 2 113514239 113514239 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 30 278 0 ENST00000302450.6:c.709C>T p.Leu237= p.L237= ENST00000302450 NM_152515.3 237 Ctg/Ttg 0 +CKM UCSF GRCh37 19 45810018 45810018 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 139 372 0 ENST00000221476.3:c.1136C>T p.Ala379Val p.A379V ENST00000221476 NM_001824.4 379 gCc/gTc 0 +CLCA2 UCSF GRCh37 1 86920950 86920950 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 332 63 560 0 ENST00000370565.4:c.2572G>A p.Glu858Lys p.E858K ENST00000370565 NM_006536.5 858 Gaa/Aaa 0 +CLCNKA UCSF GRCh37 1 16356567 16356567 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 8 72 0 ENST00000331433.4:c.1405G>A p.Ala469Thr p.A469T ENST00000331433 469 Gca/Aca 0 +CLDN25 UCSF GRCh37 11 113651151 113651151 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 63 433 0 ENST00000453129.2:c.634G>A p.Glu212Lys p.E212K ENST00000453129 NM_001101389.1 212 Gag/Aag 0 +CLEC10A UCSF GRCh37 17 6978505 6978505 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 24 158 0 ENST00000254868.4:c.819G>A p.Gly273= p.G273= ENST00000254868 NM_182906.2 273 ggG/ggA 0 +CLIP1 UCSF GRCh37 12 122825374 122825374 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 247 43 341 0 ENST00000540338.1:c.2377C>T p.Leu793Phe p.L793F ENST00000540338 793 Ctt/Ttt 0 +CLIP2 UCSF GRCh37 7 73787293 73787293 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 31 105 0 ENST00000223398.6:c.1412G>A p.Gly471Glu p.G471E ENST00000223398 NM_003388.4 471 gGg/gAg 0 +CLIP3 UCSF GRCh37 19 36508860 36508860 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 12 108 0 ENST00000360535.4:c.1217G>A p.Gly406Asp p.G406D ENST00000360535 NM_015526.2 406 gGc/gAc 0 +CLIP4 UCSF GRCh37 2 29366752 29366752 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 33 211 0 ENST00000320081.5:c.826G>A p.Ala276Thr p.A276T ENST00000320081 NM_024692.4 276 Gca/Aca 0 +CLK1 UCSF GRCh37 2 201719370 201719370 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 12 131 0 ENST00000321356.4:c.1189C>T p.Pro397Ser p.P397S ENST00000321356 NM_004071.3 397 Cct/Tct 0 +CLNK UCSF GRCh37 4 10542122 10542122 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 356 66 489 1 ENST00000226951.6:c.598C>T p.Pro200Ser p.P200S ENST00000226951 NM_052964.2 200 Ccc/Tcc 0 +CLP1 UCSF GRCh37 11 57427059 57427059 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 101 311 0 ENST00000525602.1:c.111G>A p.Leu37= p.L37= ENST00000525602 37 ttG/ttA 0 +CLRN2 UCSF GRCh37 4 17528641 17528641 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 228 28 316 0 ENST00000511148.2:c.635C>T p.Pro212Leu p.P212L ENST00000511148 NM_001079827.2 212 cCc/cTc 0 +CLSPN UCSF GRCh37 1 36215397 36215397 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 34 0 ENST00000318121.3:c.2044C>T p.Leu682Phe p.L682F ENST00000318121 NM_022111.3 682 Ctt/Ttt 0 +CLSPN UCSF GRCh37 1 36213585 36213585 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 32 209 0 ENST00000318121.3:c.2550G>A p.Lys850= p.K850= ENST00000318121 NM_022111.3 850 aaG/aaA 0 +CLSTN2 UCSF GRCh37 3 140178480 140178480 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 28 222 1 ENST00000458420.3:c.1091C>T p.Ala364Val p.A364V ENST00000458420 NM_022131.2 364 gCc/gTc 0 +CLSTN2 UCSF GRCh37 3 140282922 140282922 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 19 166 0 ENST00000458420.3:c.2602G>A p.Ala868Thr p.A868T ENST00000458420 NM_022131.2 868 Gct/Act 0 +CLTCL1 UCSF GRCh37 22 19230420 19230420 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 21 232 0 ENST00000427926.1:c.559G>A p.Asp187Asn p.D187N ENST00000427926 187 Gat/Aat 0 +CLUAP1 UCSF GRCh37 16 3582786 3582786 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 30 225 0 ENST00000576634.1:c.1037G>A p.Gly346Glu p.G346E ENST00000576634 NM_015041.2 346 gGa/gAa 0 +CLVS2 UCSF GRCh37 6 123319024 123319024 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 31 202 0 ENST00000275162.5:c.102G>A p.Val34= p.V34= ENST00000275162 NM_001010852.3 34 gtG/gtA 0 +CMYA5 UCSF GRCh37 5 79030057 79030057 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 33 355 0 ENST00000446378.2:c.5469G>A p.Lys1823= p.K1823= ENST00000446378 NM_153610.3 1823 aaG/aaA 0 +CNR1 UCSF GRCh37 6 88854268 88854268 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 33 236 0 ENST00000369499.2:c.726C>T p.Thr242= p.T242= ENST00000369499 242 acC/acT 0 +CNTN5 UCSF GRCh37 11 99715592 99715592 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 27 206 0 ENST00000524871.1:c.286G>A p.Asp96Asn p.D96N ENST00000524871 NM_014361.3 96 Gac/Aac 0 +CNTN5 UCSF GRCh37 11 99941273 99941273 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 3 18 0 ENST00000524871.1:c.1280G>A p.Gly427Glu p.G427E ENST00000524871 NM_014361.3 427 gGa/gAa 0 +CNTN6 UCSF GRCh37 3 1367580 1367580 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 208 31 312 0 ENST00000350110.2:c.1028G>A p.Gly343Glu p.G343E ENST00000350110 NM_014461.2 343 gGa/gAa 0 +COBL UCSF GRCh37 7 51096010 51096010 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 381 75 577 0 ENST00000265136.7:c.2783G>A p.Gly928Asp p.G928D ENST00000265136 NM_015198.3 928 gGt/gAt 0 +COBL UCSF GRCh37 7 51152960 51152960 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 14 57 0 ENST00000265136.7:c.999G>A p.Arg333= p.R333= ENST00000265136 NM_015198.3 333 cgG/cgA 0 +COG2 UCSF GRCh37 1 230829119 230829119 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 31 167 0 ENST00000366669.4:c.2197G>A p.Ala733Thr p.A733T ENST00000366669 NM_001145036.1 733 Gca/Aca 0 +COG2 UCSF GRCh37 1 230827142 230827142 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 13 164 0 ENST00000366669.4:c.1947C>T p.Thr649= p.T649= ENST00000366669 NM_001145036.1 649 acC/acT 0 +COL11A1 UCSF GRCh37 1 103352413 103352413 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 20 210 0 ENST00000370096.3:c.4808C>A p.Pro1603Gln p.P1603Q ENST00000370096 NM_001854.3 1603 cCa/cAa 0 +COL11A2 UCSF GRCh37 6 33143431 33143431 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 19 107 0 ENST00000374708.4:c.2038G>A p.Gly680Arg p.G680R ENST00000374708 NM_080681.2 680 Gga/Aga 0 +COL12A1 UCSF GRCh37 6 75848226 75848226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 24 228 0 ENST00000322507.8:c.5168C>T p.Ser1723Phe p.S1723F ENST00000322507 NM_004370.5 1723 tCc/tTc 0 +COL12A1 UCSF GRCh37 6 75893059 75893059 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 24 192 0 ENST00000322507.8:c.1598C>T p.Pro533Leu p.P533L ENST00000322507 NM_004370.5 533 cCt/cTt 0 +COL18A1 UCSF GRCh37 21 46925147 46925147 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 13 125 0 ENST00000359759.4:c.4213C>T p.Pro1405Ser p.P1405S ENST00000359759 1405 Cca/Tca 0 +COL20A1 UCSF GRCh37 20 61943349 61943349 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 9 65 0 ENST00000358894.6:c.1745G>A p.Arg582Lys p.R582K ENST00000358894 NM_020882.2 582 aGg/aAg 0 +COL20A1 UCSF GRCh37 20 61945187 61945187 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 9 99 0 ENST00000358894.6:c.2302G>A p.Val768Met p.V768M ENST00000358894 NM_020882.2 768 Gtg/Atg 0 +COL23A1 UCSF GRCh37 5 177684567 177684567 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 107 0 ENST00000390654.3:c.731G>A p.Gly244Asp p.G244D ENST00000390654 NM_173465.3 244 gGc/gAc 0 +COL24A1 UCSF GRCh37 1 86591741 86591741 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 22 287 0 ENST00000370571.2:c.278C>T p.Pro93Leu p.P93L ENST00000370571 NM_152890.5 93 cCt/cTt 0 +COL27A1 UCSF GRCh37 9 117068906 117068906 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 29 191 0 ENST00000356083.3:c.5045C>T p.Thr1682Ile p.T1682I ENST00000356083 NM_032888.2 1682 aCc/aTc 0 +COL28A1 UCSF GRCh37 7 7483230 7483230 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 182 21 192 0 ENST00000399429.3:c.1636C>T p.Gln546Ter p.Q546* ENST00000399429 NM_001037763.2 546 Cag/Tag 0 +COL2A1 UCSF GRCh37 12 48375911 48375911 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.00399,snp132_rs35504014 P24_Rec2 Untested WXS Illumina HiSeq 108 15 134 0 ENST00000380518.3:c.2334C>T p.Ala778= p.A778= ENST00000380518 NM_033150.2 778 gcC/gcT 0 +COL2A1 UCSF GRCh37 12 48380671 48380671 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 24 193 0 ENST00000380518.3:c.1366G>A p.Gly456Ser p.G456S ENST00000380518 NM_033150.2 456 Ggt/Agt 0 +COL3A1 UCSF GRCh37 2 189868993 189868993 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 24 98 0 ENST00000304636.3:c.2834G>A p.Gly945Asp p.G945D ENST00000304636 NM_000090.3 945 gGc/gAc 0 +COL3A1 UCSF GRCh37 2 189868138 189868138 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 11 53 0 ENST00000304636.3:c.2555G>A p.Gly852Asp p.G852D ENST00000304636 NM_000090.3 852 gGt/gAt 0 +COL4A3BP UCSF GRCh37 5 74676916 74676916 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 22 245 0 ENST00000405807.4:c.1728G>A p.Lys576= p.K576= ENST00000405807 NM_005713.2 576 aaG/aaA 0 +COL5A3 UCSF GRCh37 19 10089569 10089569 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 5 30 0 ENST00000264828.3:c.2962C>T p.Pro988Ser p.P988S ENST00000264828 NM_015719.3 988 Ccg/Tcg 0 +COL5A3 UCSF GRCh37 19 10089303 10089303 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 12 68 0 ENST00000264828.3:c.2965G>A p.Gly989Arg p.G989R ENST00000264828 NM_015719.3 989 Gga/Aga 0 +COL6A2 UCSF GRCh37 21 47546141 47546141 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 13 87 0 ENST00000300527.4:c.2412C>T p.Val804= p.V804= ENST00000300527 NM_001849.3 804 gtC/gtT 0 +COL6A3 UCSF GRCh37 2 238280963 238280963 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 17 156 0 ENST00000295550.4:c.3697G>A p.Asp1233Asn p.D1233N ENST00000295550 NM_004369.3 1233 Gac/Aac 0 +COL6A3 UCSF GRCh37 2 238242168 238242168 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 12 97 0 ENST00000295550.4:c.9253C>T p.Gln3085Ter p.Q3085* ENST00000295550 NM_004369.3 3085 Cag/Tag 0 +COL7A1 UCSF GRCh37 3 48612894 48612894 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 12 148 0 ENST00000328333.8:c.6058G>A p.Ala2020Thr p.A2020T ENST00000328333 NM_000094.3 2020 Gcc/Acc 0 +COL7A1 UCSF GRCh37 3 48618560 48618560 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 215 102 281 0 ENST00000328333.8:c.4930C>T p.Pro1644Ser p.P1644S ENST00000328333 NM_000094.3 1644 Cct/Tct 0 +COL7A1 UCSF GRCh37 3 48627934 48627934 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 306 56 477 1 ENST00000328333.8:c.1864C>T p.Pro622Ser p.P622S ENST00000328333 NM_000094.3 622 Cct/Tct 0 +COL7A1 UCSF GRCh37 3 48612931 48612931 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 17 134 0 ENST00000328333.8:c.6021C>T p.Asp2007= p.D2007= ENST00000328333 NM_000094.3 2007 gaC/gaT 0 +COL9A2 UCSF GRCh37 1 40776907 40776907 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 18 157 0 ENST00000372748.3:c.571G>A p.Val191Met p.V191M ENST00000372748 NM_001852.3 191 Gtg/Atg 0 +COLEC11 UCSF GRCh37 2 3691697 3691697 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 20 212 0 ENST00000349077.4:c.805G>A p.Glu269Lys p.E269K ENST00000349077 NM_024027.4 269 Gag/Aag 0 +COMP UCSF GRCh37 19 18895739 18895739 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 9 65 0 ENST00000222271.2:c.1881C>T p.Phe627= p.F627= ENST00000222271 NM_000095.2 627 ttC/ttT 0 +COPS5 UCSF GRCh37 8 67971558 67971558 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 446 77 707 0 ENST00000357849.4:c.266C>T p.Thr89Ile p.T89I ENST00000357849 NM_006837.2 89 aCc/aTc 0 +COPS6 UCSF GRCh37 7 99687306 99687306 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 21 203 0 ENST00000303904.3:c.271T>C p.Ser91Pro p.S91P ENST00000303904 NM_006833.4 91 Tcc/Ccc 0 +COX11 UCSF GRCh37 17 53040774 53040774 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 193 39 348 0 ENST00000299335.3:c.541G>A p.Ala181Thr p.A181T ENST00000299335 NM_004375.3 181 Gca/Aca 0 +CPA4 UCSF GRCh37 7 129950789 129950789 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 6 39 0 ENST00000222482.4:c.956G>A p.Gly319Glu p.G319E ENST00000222482 NM_016352.3 319 gGg/gAg 0 +CPAMD8 UCSF GRCh37 19 17088233 17088233 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 15 50 0 ENST00000443236.1:c.1844G>A p.Gly615Glu p.G615E ENST00000443236 NM_015692.2 615 gGa/gAa 0 +CPN1 UCSF GRCh37 10 101825120 101825120 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 4 95 0 ENST00000370418.3:c.584C>T p.Pro195Leu p.P195L ENST00000370418 NM_001308.2 195 cCc/cTc 0 +CPNE2 UCSF GRCh37 16 57144746 57144746 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 5 115 0 ENST00000290776.8:c.92G>A p.Ser31Asn p.S31N ENST00000290776 NM_152727.5 31 aGt/aAt 0 +CPNE2 UCSF GRCh37 16 57149387 57149387 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 10 168 0 ENST00000290776.8:c.361-1G>A p.X121_splice ENST00000290776 NM_152727.5 0 +CPNE3 UCSF GRCh37 8 87540889 87540889 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 6 57 0 ENST00000198765.4:c.116G>A p.Gly39Asp p.G39D ENST00000198765 39 gGt/gAt 0 +CPNE6 UCSF GRCh37 14 24542228 24542228 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 9 55 1 ENST00000397016.2:c.83G>A p.Cys28Tyr p.C28Y ENST00000397016 NM_001280558.1 28 tGc/tAc 0 +CPNE7 UCSF GRCh37 16 89642466 89642466 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 10 56 0 ENST00000268720.5:c.161G>A p.Gly54Asp p.G54D ENST00000268720 NM_014427.4 54 gGc/gAc 0 +CPS1 UCSF GRCh37 2 211512707 211512707 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 6 63 0 ENST00000233072.5:c.3262G>A p.Asp1088Asn p.D1088N ENST00000233072 NM_001875.4 1088 Gat/Aat 0 +CPSF1 UCSF GRCh37 8 145626860 145626860 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 30 271 0 ENST00000349769.3:c.270G>A p.Lys90= p.K90= ENST00000349769 NM_013291.2 90 aaG/aaA 0 +CPT1C UCSF GRCh37 19 50195544 50195544 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 29 94 0 ENST00000323446.5:c.35C>G p.Pro12Arg p.P12R ENST00000323446 NM_152359.2 12 cCc/cGc 0 +CPXCR1 UCSF GRCh37 X 88009037 88009037 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 26 181 0 ENST00000276127.4:c.622C>T p.Leu208Phe p.L208F ENST00000276127 NM_033048.5 208 Ctc/Ttc 0 +CR2 UCSF GRCh37 1 207648192 207648192 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 4 58 0 ENST00000367058.3:c.2170G>A p.Val724Met p.V724M ENST00000367058 NM_001877.4 724 Gtg/Atg 0 +CRAT UCSF GRCh37 9 131858276 131858276 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 16 142 0 ENST00000318080.2:c.1665+1G>A p.X555_splice ENST00000318080 NM_001257363.1 0 +CRB2 UCSF GRCh37 9 126135458 126135458 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 4 37 0 ENST00000373631.3:c.2648G>A p.Ser883Asn p.S883N ENST00000373631 NM_173689.5 883 aGc/aAc 0 +CREBBP UCSF GRCh37 16 3779736 3779736 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 23 219 0 ENST00000262367.5:c.5312G>A p.Ser1771Asn p.S1771N ENST00000262367 NM_004380.2 1771 aGc/aAc 0 +CRIM1 UCSF GRCh37 2 36775817 36775817 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 381 54 533 0 ENST00000280527.2:c.3084G>A p.Gln1028= p.Q1028= ENST00000280527 NM_016441.2 1028 caG/caA 0 +CRIPT UCSF GRCh37 2 46851351 46851351 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 23 279 0 ENST00000238892.3:c.291G>A p.Lys97= p.K97= ENST00000238892 NM_014171.4 97 aaG/aaA 0 +CRTC1 UCSF GRCh37 19 18870884 18870884 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 10 77 0 ENST00000321949.8:c.732G>A p.Gly244= p.G244= ENST00000321949 NM_015321.2 244 ggG/ggA 0 +CRTC2 UCSF GRCh37 1 153921856 153921856 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 17 61 0 ENST00000368633.1:c.1409T>C p.Val470Ala p.V470A ENST00000368633 NM_181715.2 470 gTc/gCc 0 +CRTC3 UCSF GRCh37 15 91150639 91150639 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 38 287 0 ENST00000268184.6:c.506G>A p.Ser169Asn p.S169N ENST00000268184 169 aGt/aAt 0 +CRYZ UCSF GRCh37 1 75190394 75190394 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 9 91 0 ENST00000340866.5:c.111+1G>A p.X37_splice ENST00000340866 NM_001889.3 0 +CSF1 UCSF GRCh37 1 110466112 110466112 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 196 31 272 0 ENST00000329608.6:c.869G>A p.Gly290Glu p.G290E ENST00000329608 NM_000757.5 290 gGg/gAg 0 +CSF2RB UCSF GRCh37 22 37325470 37325470 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 15 37 0 ENST00000403662.3:c.418C>T p.Gln140Ter p.Q140* ENST00000403662 140 Cag/Tag 0 +CSMD1 UCSF GRCh37 8 2836219 2836219 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 222 29 176 0 ENST00000537824.1:c.8481C>T p.Cys2827= p.C2827= ENST00000537824 NM_033225.5 2827 tgC/tgT 0 +CSPP1 UCSF GRCh37 8 68049803 68049803 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 12 121 0 ENST00000262210.5:c.1925G>A p.Gly642Asp p.G642D ENST00000262210 NM_024790.6 642 gGt/gAt 0 +CSRNP2 UCSF GRCh37 12 51457544 51457544 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 16 95 0 ENST00000228515.1:c.1617C>T p.Leu539= p.L539= ENST00000228515 NM_030809.2 539 ctC/ctT 0 +CTNNA2 UCSF GRCh37 2 79878746 79878746 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 12 165 0 ENST00000402739.4:c.64C>T p.Leu22= p.L22= ENST00000402739 NM_001282597.1 22 Cta/Tta 0 +CTR9 UCSF GRCh37 11 10777265 10777265 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 12 64 0 ENST00000361367.2:c.425G>A p.Gly142Asp p.G142D ENST00000361367 NM_014633.3 142 gGt/gAt 0 +CTSL1 UCSF GRCh37 9 90343719 90343719 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 335 194 674 0 ENST00000340342.6:c.616G>A p.Ala206Thr p.A206T ENST00000340342 NM_001257971.1 206 Gca/Aca 0 +CTSO UCSF GRCh37 4 156864339 156864339 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 8 192 0 ENST00000433477.3:c.213G>A p.Gln71= p.Q71= ENST00000433477 NM_001334.2 71 caG/caA 0 +CTTNBP2 UCSF GRCh37 7 117451031 117451031 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 12 101 0 ENST00000160373.3:c.202G>A p.Glu68Lys p.E68K ENST00000160373 NM_033427.2 68 Gag/Aag 0 +CTTNBP2NL UCSF GRCh37 1 112991673 112991673 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 26 134 0 ENST00000271277.6:c.209G>A p.Gly70Asp p.G70D ENST00000271277 NM_018704.2 70 gGc/gAc 0 +CUL4B UCSF GRCh37 X 119680994 119680994 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 4 35 0 ENST00000404115.3:c.827G>A p.Arg276Lys p.R276K ENST00000404115 NM_003588.3 276 aGa/aAa 0 +CUL9 UCSF GRCh37 6 43184060 43184060 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 22 250 0 ENST00000252050.4:c.6101G>A p.Gly2034Asp p.G2034D ENST00000252050 NM_015089.2 2034 gGc/gAc 0 +CUX1 UCSF GRCh37 7 101460925 101460925 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 7 55 0 ENST00000292535.7:c.6G>A p.Leu2= p.L2= ENST00000292535 NM_181552.3 2 ttG/ttA 0 +CWC27 UCSF GRCh37 5 64077783 64077783 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 17 110 0 ENST00000381070.3:c.175C>T p.Pro59Ser p.P59S ENST00000381070 NM_005869.2 59 Cct/Tct 0 +CXCL11 UCSF GRCh37 4 76956392 76956392 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 26 207 0 ENST00000306621.3:c.165C>T p.Asn55= p.N55= ENST00000306621 NM_005409.4 55 aaC/aaT 0 +CXCL2 UCSF GRCh37 4 74964383 74964383 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 18 180 0 ENST00000508487.2:c.243G>A p.Gly81= p.G81= ENST00000508487 NM_002089.3 81 ggG/ggA 0 +CXCL3 UCSF GRCh37 4 74902982 74902982 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 24 174 0 ENST00000296026.4:c.321C>T p.Asn107= p.N107= ENST00000296026 NM_002090.2 107 aaC/aaT 0 +CXorf26 UCSF GRCh37 X 75394773 75394773 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 31 120 0 ENST00000373358.3:c.145G>A p.Val49Ile p.V49I ENST00000373358 NM_016500.3 49 Gtc/Atc 0 +CXorf59 UCSF GRCh37 X 36103639 36103639 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 21 114 0 ENST00000313548.4:c.625C>T p.Leu209Phe p.L209F ENST00000313548 NM_173695.2 209 Ctt/Ttt 0 +CXXC1 UCSF GRCh37 18 47811482 47811482 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 279 57 395 0 ENST00000285106.6:c.802G>A p.Glu268Lys p.E268K ENST00000285106 NM_001101654.1 268 Gag/Aag 0 +CYB561 UCSF GRCh37 17 61514898 61514898 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 4 51 0 ENST00000360793.3:c.11G>A p.Gly4Glu p.G4E ENST00000360793 NM_001915.3 4 gGg/gAg 0 +CYB5D1 UCSF GRCh37 17 7761524 7761524 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 5 40 0 ENST00000332439.4:c.72G>A p.Glu24= p.E24= ENST00000332439 NM_144607.4 24 gaG/gaA 0 +CYB5R1 UCSF GRCh37 1 202931713 202931713 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 18 119 0 ENST00000367249.4:c.860C>T p.Ala287Val p.A287V ENST00000367249 NM_016243.2 287 gCc/gTc 0 +CYB5R4 UCSF GRCh37 6 84574011 84574011 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 84 0 ENST00000369681.5:c.193C>T p.His65Tyr p.H65Y ENST00000369681 NM_016230.3 65 Cac/Tac 0 +CYFIP1 UCSF GRCh37 15 22993035 22993035 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 33 0 ENST00000313077.7:c.2922G>A p.Glu974= p.E974= ENST00000313077 NM_014608.2 974 gaG/gaA 0 +CYLD UCSF GRCh37 16 50810181 50810181 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 4 61 0 ENST00000311559.9:c.1014G>A p.Lys338= p.K338= ENST00000311559 NM_015247.2 338 aaG/aaA 0 +CYP24A1 UCSF GRCh37 20 52789884 52789884 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 310 37 403 0 ENST00000216862.3:c.235C>T p.Leu79Phe p.L79F ENST00000216862 NM_000782.4 79 Ctc/Ttc 0 +CYP3A7 UCSF GRCh37 7 99306796 99306796 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 47 338 0 ENST00000336374.2:c.1115G>A p.Arg372Lys p.R372K ENST00000336374 NM_000765.3 372 aGa/aAa 0 +CYP46A1 UCSF GRCh37 14 100187631 100187631 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 11 109 0 ENST00000261835.3:c.1036G>A p.Asp346Asn p.D346N ENST00000261835 NM_006668.1 346 Gac/Aac 0 +CYP4F11 UCSF GRCh37 19 16045165 16045165 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 13 52 0 ENST00000248041.8:c.54G>A p.Pro18= p.P18= ENST00000248041 NM_001128932.1 18 ccG/ccA 0 +CYP4F2 UCSF GRCh37 19 15989703 15989703 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 5 17 0 ENST00000221700.6:c.1441G>A p.Val481Ile p.V481I ENST00000221700 NM_001082.3 481 Gtc/Atc 0 +CYTH1 UCSF GRCh37 17 76697834 76697834 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 30 95 0 ENST00000361101.4:c.357-1G>A p.X119_splice ENST00000361101 NM_017456.2 0 +CYTIP UCSF GRCh37 2 158290915 158290915 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 95 427 0 ENST00000264192.3:c.246G>A p.Lys82= p.K82= ENST00000264192 NM_004288.4 82 aaG/aaA 0 +DAAM2 UCSF GRCh37 6 39846317 39846317 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 11 103 0 ENST00000274867.4:c.1498G>A p.Ala500Thr p.A500T ENST00000274867 NM_001201427.1 500 Gct/Act 0 +DACT2 UCSF GRCh37 6 168709332 168709332 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 332 38 437 1 ENST00000366795.3:c.1105G>A p.Gly369Ser p.G369S ENST00000366795 NM_214462.3 369 Ggt/Agt 0 +DAGLA UCSF GRCh37 11 61502445 61502445 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 33 214 0 ENST00000257215.5:c.1099G>A p.Asp367Asn p.D367N ENST00000257215 NM_006133.2 367 Gac/Aac 0 +DAGLA UCSF GRCh37 11 61511131 61511131 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 4 59 0 ENST00000257215.5:c.2299G>A p.Ala767Thr p.A767T ENST00000257215 NM_006133.2 767 Gcg/Acg 0 +DAK UCSF GRCh37 11 61113195 61113195 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 32 299 0 ENST00000394900.3:c.1463C>T p.Ala488Val p.A488V ENST00000394900 NM_015533.3 488 gCt/gTt 0 +DAK UCSF GRCh37 11 61108958 61108958 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 24 196 0 ENST00000394900.3:c.537G>A p.Lys179= p.K179= ENST00000394900 NM_015533.3 179 aaG/aaA 0 +DAOA UCSF GRCh37 13 106125018 106125018 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 3 47 0 ENST00000375936.3:c.265C>T p.Pro89Ser p.P89S ENST00000375936 NM_001161812.1 89 Cct/Tct 0 +DAP3 UCSF GRCh37 1 155695795 155695795 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 13 150 0 ENST00000343043.3:c.457C>T p.Leu153= p.L153= ENST00000343043 NM_033657.2 153 Cta/Tta 0 +DARS2 UCSF GRCh37 1 173825858 173825858 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 21 216 0 ENST00000361951.4:c.1729C>T p.Pro577Ser p.P577S ENST00000361951 NM_018122.4 577 Cct/Tct 0 +DAXX UCSF GRCh37 6 33286520 33286520 + stop_retained_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 16 82 0 ENST00000266000.6:c.2223G>A p.Ter741= p.*741= ENST00000266000 741 taG/taA 0 +DBC1 UCSF GRCh37 9 121929590 121929590 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 31 279 0 ENST00000265922.3:c.2058C>T p.Phe686= p.F686= ENST00000265922 NM_014618.2 686 ttC/ttT 0 +DBR1 UCSF GRCh37 3 137881420 137881420 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 9 82 0 ENST00000260803.4:c.946G>A p.Asp316Asn p.D316N ENST00000260803 NM_016216.3 316 Gat/Aat 0 +DBR1 UCSF GRCh37 3 137885932 137885932 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 8 70 0 ENST00000260803.4:c.705G>A p.Met235Ile p.M235I ENST00000260803 NM_016216.3 235 atG/atA 0 +DCAF6 UCSF GRCh37 1 167921037 167921037 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 13 149 0 ENST00000312263.6:c.98-1G>A p.X33_splice ENST00000312263 NM_001017977.2 0 +DCHS1 UCSF GRCh37 11 6645226 6645226 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 30 302 0 ENST00000299441.3:c.7681G>A p.Asp2561Asn p.D2561N ENST00000299441 NM_003737.2 2561 Gac/Aac 0 +DCLK2 UCSF GRCh37 4 151145687 151145687 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 16 148 0 ENST00000296550.7:c.1276G>A p.Asp426Asn p.D426N ENST00000296550 NM_001040260.3 426 Gac/Aac 0 +DCLK3 UCSF GRCh37 3 36779519 36779519 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 127 467 0 ENST00000416516.2:c.632C>T p.Thr211Ile p.T211I ENST00000416516 NM_033403.1 211 aCt/aTt 0 +DCLRE1A UCSF GRCh37 10 115603981 115603981 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 12 113 0 ENST00000361384.2:c.2401C>T p.Leu801Phe p.L801F ENST00000361384 NM_014881.4 801 Ctc/Ttc 0 +DCST1 UCSF GRCh37 1 155019721 155019721 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 30 235 0 ENST00000295542.1:c.1545G>A p.Arg515= p.R515= ENST00000295542 NM_152494.3 515 cgG/cgA 0 +DCST2 UCSF GRCh37 1 155002654 155002654 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 12 117 0 ENST00000368424.3:c.1083C>T p.Ser361= p.S361= ENST00000368424 NM_144622.2 361 agC/agT 0 +DCT UCSF GRCh37 13 95114294 95114294 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 26 194 0 ENST00000377028.5:c.1013C>T p.Pro338Leu p.P338L ENST00000377028 NM_001922.3 338 cCc/cTc 0 +DCTN2 UCSF GRCh37 12 57927880 57927880 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 685 80 117 0 ENST00000548249.1:c.525G>A p.Lys175= p.K175= ENST00000548249 NM_001261412.1 175 aaG/aaA 0 +DDIT4 UCSF GRCh37 10 74034840 74034840 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 138 42 330 0 ENST00000307365.3:c.593C>T p.Ser198Phe p.S198F ENST00000307365 NM_019058.2 198 tCt/tTt 0 +DDOST UCSF GRCh37 1 20982629 20982629 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 12 50 0 ENST00000375048.3:c.368G>A p.Gly123Glu p.G123E ENST00000375048 NM_005216.4 123 gGa/gAa 0 +DDX18 UCSF GRCh37 2 118575155 118575155 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 10 49 0 ENST00000263239.2:c.221C>T p.Ser74Phe p.S74F ENST00000263239 NM_006773.3 74 tCt/tTt 0 +DDX39B UCSF GRCh37 6 31498696 31498696 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 20 135 0 ENST00000396172.1:c.1130G>A p.Arg377Lys p.R377K ENST00000396172 NM_004640.6 377 aGa/aAa 0 +DDX39B UCSF GRCh37 6 31504281 31504281 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 460 58 687 0 ENST00000396172.1:c.612G>A p.Gln204= p.Q204= ENST00000396172 NM_004640.6 204 caG/caA 0 +DDX54 UCSF GRCh37 12 113602091 113602091 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 15 124 0 ENST00000306014.5:c.1720-1G>A p.X574_splice ENST00000306014 NM_024072.3 0 +DDX60L UCSF GRCh37 4 169294816 169294816 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 62 491 0 ENST00000260184.7:c.4776+1G>A p.X1592_splice ENST00000260184 NM_001012967.1 0 +DECR2 UCSF GRCh37 16 461398 461398 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 24 146 0 ENST00000219481.5:c.699C>T p.Ala233= p.A233= ENST00000219481 NM_020664.3 233 gcC/gcT 0 +DEFA5 UCSF GRCh37 8 6914189 6914189 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 32 0 ENST00000330590.2:c.31C>T p.Leu11Phe p.L11F ENST00000330590 NM_021010.1 11 Ctc/Ttc 0 +DEGS1 UCSF GRCh37 1 224377858 224377858 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 258 53 384 0 ENST00000323699.4:c.662G>A p.Gly221Asp p.G221D ENST00000323699 NM_003676.3 221 gGt/gAt 0 +DENND1A UCSF GRCh37 9 126144555 126144555 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 19 151 0 ENST00000373624.2:c.2186C>T p.Ala729Val p.A729V ENST00000373624 NM_020946.1 729 gCc/gTc 0 +DENND2A UCSF GRCh37 7 140301242 140301242 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 13 103 0 ENST00000275884.6:c.956G>A p.Arg319Lys p.R319K ENST00000275884 319 aGa/aAa 0 +DENND4A UCSF GRCh37 15 65994642 65994642 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 61 0 ENST00000431932.2:c.2430+1G>A p.X810_splice ENST00000431932 NM_005848.3 0 +DENND5B UCSF GRCh37 12 31555512 31555512 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 18 168 0 ENST00000389082.5:c.2869C>T p.Pro957Ser p.P957S ENST00000389082 NM_144973.3 957 Cct/Tct 0 +DENND5B UCSF GRCh37 12 31552652 31552652 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 14 126 0 ENST00000389082.5:c.3004C>T p.Leu1002= p.L1002= ENST00000389082 NM_144973.3 1002 Ctg/Ttg 0 +DEPDC7 UCSF GRCh37 11 33054986 33054986 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 243 47 377 0 ENST00000241051.3:c.1521G>A p.Glu507= p.E507= ENST00000241051 NM_001077242.1 507 gaG/gaA 0 +DES UCSF GRCh37 2 220286117 220286117 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 47 154 0 ENST00000373960.3:c.1079C>T p.Ala360Val p.A360V ENST00000373960 NM_001927.3 360 gCc/gTc 0 +DFFB UCSF GRCh37 1 3775390 3775390 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 25 139 0 ENST00000378209.3:c.223G>A p.Gly75Ser p.G75S ENST00000378209 NM_004402.2 75 Ggc/Agc 0 +DHRS4L1 UCSF GRCh37 14 24505775 24505775 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 62 195 0 ENST00000606840.1:n.66C>T *22* ENST00000606840 0 +DHTKD1 UCSF GRCh37 10 12160815 12160815 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 211 40 159 0 ENST00000263035.4:c.2470G>A p.Gly824Arg p.G824R ENST00000263035 NM_018706.6 824 Ggg/Agg 0 +DHX15 UCSF GRCh37 4 24529649 24529649 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 18 165 0 ENST00000336812.4:c.2286C>T p.Ala762= p.A762= ENST00000336812 NM_001358.2 762 gcC/gcT 0 +DHX33 UCSF GRCh37 17 5358557 5358557 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 17 194 0 ENST00000225296.3:c.1070C>T p.Ala357Val p.A357V ENST00000225296 NM_001199699.1 357 gCt/gTt 0 +DHX58 UCSF GRCh37 17 40253810 40253810 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 10 100 0 ENST00000251642.3:c.2006C>T p.Ala669Val p.A669V ENST00000251642 NM_024119.2 669 gCc/gTc 0 +DIDO1 UCSF GRCh37 20 61542417 61542417 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 219 36 321 0 ENST00000266070.4:c.548G>A p.Gly183Glu p.G183E ENST00000266070 NM_033081.2 183 gGg/gAg 0 +DIEXF UCSF GRCh37 1 210010214 210010214 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 219 112 464 0 ENST00000491415.2:c.720G>A p.Lys240= p.K240= ENST00000491415 NM_014388.6 240 aaG/aaA 0 +DIP2B UCSF GRCh37 12 51097957 51097957 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 16 96 0 ENST00000301180.5:c.2360G>A p.Gly787Glu p.G787E ENST00000301180 NM_173602.2 787 gGg/gAg 0 +DIP2C UCSF GRCh37 10 329328 329328 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 8 59 0 ENST00000280886.6:c.4178C>T p.Ser1393Phe p.S1393F ENST00000280886 NM_014974.2 1393 tCc/tTc 0 +DIRAS1 UCSF GRCh37 19 2717666 2717666 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 196 22 154 0 ENST00000323469.4:c.139G>A p.Val47Met p.V47M ENST00000323469 NM_145173.3 47 Gtg/Atg 0 +DIS3L UCSF GRCh37 15 66587480 66587480 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 13 130 0 ENST00000319212.4:c.293+1G>A p.X98_splice ENST00000319212 NM_001143688.1 0 +DLAT UCSF GRCh37 11 111896382 111896382 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 17 110 0 ENST00000280346.6:c.186C>T p.Thr62= p.T62= ENST00000280346 NM_001931.4 62 acC/acT 0 +DLC1 UCSF GRCh37 8 12957533 12957533 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 299 36 333 0 ENST00000276297.4:c.2313G>A p.Arg771= p.R771= ENST00000276297 NM_182643.2 771 cgG/cgA 0 +DMAP1 UCSF GRCh37 1 44684349 44684349 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 240 41 358 0 ENST00000315913.5:c.642G>A p.Lys214= p.K214= ENST00000315913 214 aaG/aaA 0 +DMPK UCSF GRCh37 19 46281768 46281768 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 14 115 0 ENST00000291270.4:c.564G>A p.Arg188= p.R188= ENST00000291270 NM_004409.3 188 cgG/cgA 0 +DMRTA2 UCSF GRCh37 1 50886967 50886967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 24 220 0 ENST00000404795.3:c.242C>T p.Ala81Val p.A81V ENST00000404795 NM_032110.2 81 gCc/gTc 0 +DMTF1 UCSF GRCh37 7 86822635 86822635 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 21 174 0 ENST00000331242.7:c.1616C>T p.Ala539Val p.A539V ENST00000331242 NM_001142326.1 539 gCt/gTt 0 +DMXL1 UCSF GRCh37 5 118407301 118407301 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 20 161 0 ENST00000311085.8:c.37C>T p.Pro13Ser p.P13S ENST00000311085 NM_005509.4 13 Cct/Tct 0 +DNAH1 UCSF GRCh37 3 52386630 52386630 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 8 51 0 ENST00000420323.2:c.2934G>A p.Glu978= p.E978= ENST00000420323 NM_015512.4 978 gaG/gaA 0 +DNAH1 UCSF GRCh37 3 52398656 52398656 + splice_region_variant,synonymous_variant Splice_Region SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 48 140 1 ENST00000420323.2:c.5247T>C p.Asp1749= p.D1749= ENST00000420323 NM_015512.4 1749 gaT/gaC 0 +DNAH10 UCSF GRCh37 12 124413843 124413843 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 474 74 603 0 ENST00000409039.3:c.11974G>A p.Gly3992Arg p.G3992R ENST00000409039 NM_207437.3 3992 Ggg/Agg 0 +DNAH10 UCSF GRCh37 12 124311386 124311386 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 4 50 0 ENST00000409039.3:c.3978G>A p.Lys1326= p.K1326= ENST00000409039 NM_207437.3 1326 aaG/aaA 0 +DNAH2 UCSF GRCh37 17 7636501 7636501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 604 100 719 0 ENST00000389173.2:c.496C>T p.Pro166Ser p.P166S ENST00000389173 NM_020877.2 166 Ccc/Tcc 0 +DNAH2 UCSF GRCh37 17 7696469 7696469 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 274 48 460 0 ENST00000389173.2:c.7515G>A p.Trp2505Ter p.W2505* ENST00000389173 NM_020877.2 2505 tgG/tgA 0 +DNAH2 UCSF GRCh37 17 7663129 7663129 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 552 79 775 0 ENST00000389173.2:c.2658G>A p.Leu886= p.L886= ENST00000389173 NM_020877.2 886 ctG/ctA 0 +DNAH6 UCSF GRCh37 2 84774620 84774620 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 21 254 0 ENST00000237449.6:c.1070C>T p.Thr357Ile p.T357I ENST00000237449 357 aCa/aTa 0 +DNAH8 UCSF GRCh37 6 38840477 38840477 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 26 247 0 ENST00000359357.3:c.6505G>A p.Gly2169Ser p.G2169S ENST00000359357 2169 Ggc/Agc 0 +DNAH8 UCSF GRCh37 6 38690630 38690630 + upstream_gene_variant 5'Flank SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 43 0 ENST00000359357 0 +DNAJB1 UCSF GRCh37 19 14627575 14627575 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 16 113 0 ENST00000254322.2:c.495C>T p.Thr165= p.T165= ENST00000254322 NM_006145.1 165 acC/acT 0 +DNAJB7 UCSF GRCh37 22 41257988 41257988 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 19 183 0 ENST00000307221.4:c.11A>G p.Tyr4Cys p.Y4C ENST00000307221 NM_145174.1 4 tAc/tGc 0 +DNAJC2 UCSF GRCh37 7 102957322 102957322 + stop_gained Nonsense_Mutation SNP A A C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 39 133 0 ENST00000379263.3:c.1382T>G p.Leu461Ter p.L461* ENST00000379263 NM_014377.1 461 tTa/tGa 0 +DNAJC6 UCSF GRCh37 1 65855296 65855296 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 12 126 0 ENST00000395325.3:c.1283C>T p.Ser428Phe p.S428F ENST00000395325 NM_014787.3 428 tCt/tTt 0 +DNASE1 UCSF GRCh37 16 3707321 3707321 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 8 47 0 ENST00000246949.5:c.683C>T p.Pro228Leu p.P228L ENST00000246949 NM_005223.3 228 cCc/cTc 0 +DNHD1 UCSF GRCh37 11 6540976 6540976 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 59 163 0 ENST00000254579.6:c.1539G>A p.Trp513Ter p.W513* ENST00000254579 NM_144666.2 513 tgG/tgA 0 +DNM2 UCSF GRCh37 19 10934513 10934513 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 301 35 308 0 ENST00000355667.6:c.1831G>A p.Glu611Lys p.E611K ENST00000355667 NM_001005360.2 611 Gaa/Aaa 0 +DOCK11 UCSF GRCh37 X 117707891 117707891 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 16 92 0 ENST00000276202.7:c.1299C>T p.Thr433= p.T433= ENST00000276202 NM_144658.3 433 acC/acT 0 +DOCK3 UCSF GRCh37 3 51112786 51112786 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 11 103 0 ENST00000266037.9:c.465-1G>A p.X155_splice ENST00000266037 NM_004947.4 0 +DOCK5 UCSF GRCh37 8 25168013 25168013 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 198 24 213 0 ENST00000276440.7:c.1283C>T p.Ala428Val p.A428V ENST00000276440 NM_024940.6 428 gCc/gTc 0 +DOK2 UCSF GRCh37 8 21767047 21767047 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 49 172 0 ENST00000276420.4:c.1014C>T p.Pro338= p.P338= ENST00000276420 NM_003974.2 338 ccC/ccT 0 +DOLPP1 UCSF GRCh37 9 131847825 131847825 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 32 94 0 ENST00000372546.4:c.391C>T p.Leu131= p.L131= ENST00000372546 NM_020438.4 131 Ctg/Ttg 0 +DPEP3 UCSF GRCh37 16 68012174 68012174 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 10 119 0 ENST00000268793.4:c.757C>T p.Pro253Ser p.P253S ENST00000268793 NM_022357.3 253 Cca/Tca 0 +DPF2 UCSF GRCh37 11 65113252 65113252 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 12 110 0 ENST00000528416.1:c.753C>T p.Ser251= p.S251= ENST00000528416 NM_006268.4 251 tcC/tcT 0 +DPP8 UCSF GRCh37 15 65777486 65777486 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 18 234 0 ENST00000341861.5:c.1016C>T p.Pro339Leu p.P339L ENST00000341861 NM_197960.2 339 cCt/cTt 0 +DPP9 UCSF GRCh37 19 4704019 4704019 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 11 99 0 ENST00000598800.1:c.561C>T p.Pro187= p.P187= ENST00000598800 187 ccC/ccT 0 +DRD1 UCSF GRCh37 5 174869973 174869973 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 12 156 0 ENST00000393752.2:c.130G>A p.Val44Ile p.V44I ENST00000393752 NM_000794.3 44 Gtc/Atc 0 +DROSHA UCSF GRCh37 5 31435970 31435970 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 19 67 0 ENST00000344624.3:c.2944G>A p.Val982Ile p.V982I ENST00000344624 982 Gtc/Atc 0 +DSCAM UCSF GRCh37 21 41496237 41496237 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 7 60 0 ENST00000400454.1:c.3581G>A p.Gly1194Asp p.G1194D ENST00000400454 NM_001271534.1 1194 gGt/gAt 0 +DSCAM UCSF GRCh37 21 41711201 41711201 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 20 186 0 ENST00000400454.1:c.1352G>A p.Gly451Asp p.G451D ENST00000400454 NM_001271534.1 451 gGc/gAc 0 +DSCAM UCSF GRCh37 21 41710220 41710220 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 25 250 0 ENST00000400454.1:c.1591C>T p.Pro531Ser p.P531S ENST00000400454 NM_001271534.1 531 Ccg/Tcg 0 +DSCAM UCSF GRCh37 21 41725552 41725552 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 18 111 0 ENST00000400454.1:c.774G>A p.Trp258Ter p.W258* ENST00000400454 NM_001271534.1 258 tgG/tgA 0 +DSG2 UCSF GRCh37 18 29121189 29121189 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 17 87 0 ENST00000261590.8:c.1913G>A p.Gly638Glu p.G638E ENST00000261590 NM_001943.3 638 gGa/gAa 0 +DST UCSF GRCh37 6 56334743 56334743 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 34 277 0 ENST00000244364.6:c.14620G>A p.Val4874Ile p.V4874I ENST00000244364 NM_015548.4 4874 Gta/Ata 0 +DSTYK UCSF GRCh37 1 205126440 205126440 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 24 237 0 ENST00000367162.3:c.2313G>A p.Gln771= p.Q771= ENST00000367162 NM_015375.2 771 caG/caA 0 +DTX1 UCSF GRCh37 12 113515352 113515352 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 22 213 0 ENST00000257600.3:c.383C>T p.Thr128Ile p.T128I ENST00000257600 NM_004416.2 128 aCc/aTc 0 +DUOXA1 UCSF GRCh37 15 45410176 45410176 + downstream_gene_variant 3'Flank SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 5 71 0 ENST00000560572 NM_001276266.1 0 +DUS4L UCSF GRCh37 7 107211613 107211613 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 8 52 0 ENST00000265720.3:c.140G>A p.Arg47Lys p.R47K ENST00000265720 NM_001270419.1 47 aGa/aAa 0 +DUS4L UCSF GRCh37 7 107217867 107217867 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 59 236 0 ENST00000265720.3:c.816G>A p.Gly272= p.G272= ENST00000265720 NM_001270419.1 272 ggG/ggA 0 +DUSP13 UCSF GRCh37 10 76854607 76854607 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 47 0 ENST00000372702.3:c.*732G>A *244* ENST00000372702 0 +DUSP6 UCSF GRCh37 12 89745677 89745677 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 263 30 358 0 ENST00000279488.7:c.140C>T p.Ser47Leu p.S47L ENST00000279488 NM_001946.2 47 tCg/tTg 0 +DVL1 UCSF GRCh37 1 1275467 1275467 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 6 44 0 ENST00000378888.5:c.860G>A p.Gly287Glu p.G287E ENST00000378888 287 gGg/gAg 0 +DVL3 UCSF GRCh37 3 183888396 183888396 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 56 452 1 ENST00000313143.3:c.2004G>A p.Met668Ile p.M668I ENST00000313143 NM_004423.3 668 atG/atA 0 +DVL3 UCSF GRCh37 3 183882976 183882976 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 27 171 0 ENST00000313143.3:c.675G>A p.Lys225= p.K225= ENST00000313143 NM_004423.3 225 aaG/aaA 0 +DYNC1H1 UCSF GRCh37 14 102452456 102452456 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 234 34 322 0 ENST00000360184.4:c.1894G>A p.Ala632Thr p.A632T ENST00000360184 NM_001376.4 632 Gct/Act 0 +DYNC2H1 UCSF GRCh37 11 103005056 103005056 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 25 185 0 ENST00000375735.2:c.2113G>A p.Val705Ile p.V705I ENST00000375735 NM_001080463.1 705 Gtt/Att 0 +DYNC2H1 UCSF GRCh37 11 103107235 103107235 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 13 157 0 ENST00000375735.2:c.9786C>T p.Asp3262= p.D3262= ENST00000375735 NM_001080463.1 3262 gaC/gaT 0 +DYSF UCSF GRCh37 2 71795384 71795384 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 23 235 1 ENST00000258104.3:c.2726G>A p.Gly909Asp p.G909D ENST00000258104 NM_003494.3 909 gGc/gAc 0 +DYSF UCSF GRCh37 2 71766326 71766326 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 257 40 386 0 ENST00000258104.3:c.1437C>T p.Tyr479= p.Y479= ENST00000258104 NM_003494.3 479 taC/taT 0 +DYX1C1 UCSF GRCh37 15 55790479 55790479 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 74 232 0 ENST00000321149.3:c.49G>A p.Val17Ile p.V17I ENST00000321149 NM_130810.3 17 Gtc/Atc 0 +DYX1C1 UCSF GRCh37 15 55790464 55790464 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 24 218 0 ENST00000321149.3:c.64C>T p.Pro22Ser p.P22S ENST00000321149 NM_130810.3 22 Ccc/Tcc 0 +E2F2 UCSF GRCh37 1 23848374 23848374 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 24 176 0 ENST00000361729.2:c.533G>A p.Gly178Asp p.G178D ENST00000361729 NM_004091.3 178 gGc/gAc 0 +E2F3 UCSF GRCh37 6 20490487 20490487 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 28 262 0 ENST00000346618.3:c.1224G>A p.Gln408= p.Q408= ENST00000346618 NM_001949.4 408 caG/caA 0 +E2F7 UCSF GRCh37 12 77421803 77421803 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 29 268 0 ENST00000322886.7:c.2000G>A p.Gly667Glu p.G667E ENST00000322886 NM_203394.2 667 gGa/gAa 0 +E2F7 UCSF GRCh37 12 77423701 77423701 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 10 57 0 ENST00000322886.7:c.1794G>A p.Glu598= p.E598= ENST00000322886 NM_203394.2 598 gaG/gaA 0 +EARS2 UCSF GRCh37 16 23540917 23540917 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 10 114 0 ENST00000449606.1:c.1258G>A p.Val420Ile p.V420I ENST00000449606 NM_001083614.1 420 Gta/Ata 0 +EARS2 UCSF GRCh37 16 23563625 23563625 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 36 116 0 ENST00000449606.1:c.140G>A p.Gly47Asp p.G47D ENST00000449606 NM_001083614.1 47 gGc/gAc 0 +EBAG9 UCSF GRCh37 8 110573142 110573142 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 20 206 0 ENST00000337573.5:c.505G>A p.Ala169Thr p.A169T ENST00000337573 NM_004215.4 169 Gca/Aca 0 +ECM2 UCSF GRCh37 9 95277008 95277008 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 303 47 436 0 ENST00000344604.5:c.959G>A p.Cys320Tyr p.C320Y ENST00000344604 NM_001393.3 320 tGc/tAc 0 +EDC3 UCSF GRCh37 15 74925151 74925151 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 65 180 0 ENST00000315127.4:c.1329C>T p.Asp443= p.D443= ENST00000315127 NM_025083.3 443 gaC/gaT 0 +EEF2 UCSF GRCh37 19 3979880 3979880 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 7 52 0 ENST00000309311.6:c.1531G>A p.Ala511Thr p.A511T ENST00000309311 NM_001961.3 511 Gcc/Acc 0 +EEFSEC UCSF GRCh37 3 128060196 128060196 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 20 211 0 ENST00000254730.6:c.907G>A p.Val303Met p.V303M ENST00000254730 NM_021937.3 303 Gtg/Atg 0 +EFCAB5 UCSF GRCh37 17 28380852 28380852 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 338 47 486 0 ENST00000394835.3:c.1880G>A p.Gly627Glu p.G627E ENST00000394835 NM_198529.3 627 gGa/gAa 0 +EFEMP1 UCSF GRCh37 2 56094295 56094295 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 12 140 0 ENST00000355426.3:c.1395G>A p.Leu465= p.L465= ENST00000355426 465 ctG/ctA 0 +EFNB1 UCSF GRCh37 X 68058563 68058563 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 7 72 0 ENST00000204961.4:c.232C>T p.Leu78= p.L78= ENST00000204961 NM_004429.4 78 Ctg/Ttg 0 +EFNB3 UCSF GRCh37 17 7608984 7608984 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 19 141 0 ENST00000226091.2:c.68G>A p.Gly23Glu p.G23E ENST00000226091 NM_001406.3 23 gGg/gAg 0 +EGF UCSF GRCh37 4 110884380 110884380 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 15 87 0 ENST00000265171.5:c.1364G>A p.Ser455Asn p.S455N ENST00000265171 NM_001963.4 455 aGc/aAc 0 +EGFL7 UCSF GRCh37 9 139564675 139564675 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 19 94 1 ENST00000308874.7:c.464C>T p.Thr155Ile p.T155I ENST00000308874 155 aCc/aTc 0 +EGR2 UCSF GRCh37 10 64574184 64574184 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 7 70 0 ENST00000242480.3:c.214G>A p.Asp72Asn p.D72N ENST00000242480 NM_001136177.1 72 Gat/Aat 0 +EHHADH UCSF GRCh37 3 184922287 184922287 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 20 116 0 ENST00000231887.3:c.827G>A p.Arg276Lys p.R276K ENST00000231887 NM_001166415.1 276 aGg/aAg 0 +EHHADH UCSF GRCh37 3 184922469 184922469 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 37 230 0 ENST00000231887.3:c.645G>A p.Glu215= p.E215= ENST00000231887 NM_001166415.1 215 gaG/gaA 0 +EHMT2 UCSF GRCh37 6 31860229 31860229 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 38 123 0 ENST00000375537.4:c.819C>T p.Tyr273= p.Y273= ENST00000375537 NM_006709.3 273 taC/taT 0 +EIF2B4 UCSF GRCh37 2 27590049 27590049 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 31 268 0 ENST00000347454.4:c.905C>T p.Ala302Val p.A302V ENST00000347454 NM_015636.3 302 gCa/gTa 0 +EIF5A UCSF GRCh37 17 7210382 7210382 + upstream_gene_variant 5'Flank SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 39 78 0 ENST00000336458 NM_001970.4 0 +ELF5 UCSF GRCh37 11 34515099 34515099 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 22 251 0 ENST00000312319.2:c.312G>A p.Gln104= p.Q104= ENST00000312319 NM_001243081.1 104 caG/caA 0 +ELMO2 UCSF GRCh37 20 44999118 44999118 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 315 49 415 0 ENST00000290246.6:c.1848C>T p.Pro616= p.P616= ENST00000290246 NM_133171.3 616 ccC/ccT 0 +ELMO3 UCSF GRCh37 16 67237579 67237579 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 40 376 0 ENST00000393997.2:c.2121G>A p.Trp707Ter p.W707* ENST00000393997 NM_024712.3 707 tgG/tgA 0 +ELP3 UCSF GRCh37 8 27987165 27987165 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 22 93 0 ENST00000256398.8:c.764C>T p.Ala255Val p.A255V ENST00000256398 NM_018091.5 255 gCt/gTt 0 +EMILIN3 UCSF GRCh37 20 39989948 39989948 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 12 119 0 ENST00000332312.3:c.2261C>T p.Ala754Val p.A754V ENST00000332312 NM_052846.1 754 gCc/gTc 0 +EML3 UCSF GRCh37 11 62371283 62371283 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 49 436 1 ENST00000394773.2:c.2175C>T p.His725= p.H725= ENST00000394773 NM_153265.2 725 caC/caT 0 +EMR3 UCSF GRCh37 19 14755077 14755077 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 10 27 0 ENST00000253673.5:c.893G>A p.Ser298Asn p.S298N ENST00000253673 NM_032571.3 298 aGt/aAt 0 +ENPEP UCSF GRCh37 4 111430940 111430940 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 17 127 0 ENST00000265162.5:c.1171G>A p.Val391Ile p.V391I ENST00000265162 NM_001977.3 391 Gtt/Att 0 +ENTPD5 UCSF GRCh37 14 74436818 74436818 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 12 189 0 ENST00000334696.6:c.1095C>T p.Asn365= p.N365= ENST00000334696 NM_001249.2 365 aaC/aaT 0 +ENTPD8 UCSF GRCh37 9 140332632 140332632 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 5 42 0 ENST00000371506.2:c.106C>T p.Leu36Phe p.L36F ENST00000371506 NM_001033113.1 36 Ctc/Ttc 0 +EOMES UCSF GRCh37 3 27761734 27761734 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 15 133 0 ENST00000295743.4:c.964G>A p.Ala322Thr p.A322T ENST00000295743 NM_005442.3 322 Gcg/Acg 0 +EPC2 UCSF GRCh37 2 149542240 149542240 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 313 41 450 0 ENST00000258484.6:c.2021C>T p.Thr674Ile p.T674I ENST00000258484 NM_015630.3 674 aCc/aTc 0 +EPC2 UCSF GRCh37 2 149526793 149526793 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 23 210 0 ENST00000258484.6:c.1214G>A p.Gly405Glu p.G405E ENST00000258484 NM_015630.3 405 gGa/gAa 0 +EPHA5 UCSF GRCh37 4 66467870 66467870 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 28 242 0 ENST00000273854.3:c.399C>T p.Thr133= p.T133= ENST00000273854 NM_004439.5 133 acC/acT 0 +EPHA7 UCSF GRCh37 6 94124467 94124470 + protein_altering_variant In_Frame_Del DEL TTAG TTAG A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 0 ENST00000369303.4:c.113_116delinsT p.Ser38_Lys39delinsLeu p.S38_K39delinsL ENST00000369303 NM_004440.3 38 tCTAAa/tTa 0 +EPHB3 UCSF GRCh37 3 184298276 184298276 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 22 170 0 ENST00000330394.2:c.2259C>T p.Asn753= p.N753= ENST00000330394 NM_004443.3 753 aaC/aaT 0 +EPHB4 UCSF GRCh37 7 100402857 100402857 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 101 342 1 ENST00000358173.3:c.2765G>A p.Gly922Glu p.G922E ENST00000358173 NM_004444.4 922 gGa/gAa 0 +EPHB6 UCSF GRCh37 7 142566777 142566777 + synonymous_variant Silent SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 39 107 0 ENST00000392957.2:c.2334A>T p.Gly778= p.G778= ENST00000392957 NM_004445.4 778 ggA/ggT 0 +EPM2AIP1 UCSF GRCh37 3 37033028 37033028 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 401 57 586 0 ENST00000322716.5:c.1541C>T p.Thr514Ile p.T514I ENST00000322716 NM_014805.3 514 aCt/aTt 0 +EPOR UCSF GRCh37 19 11494794 11494794 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 15 116 0 ENST00000222139.6:c.90C>T p.Leu30= p.L30= ENST00000222139 NM_000121.3 30 ctC/ctT 0 +EPS15 UCSF GRCh37 1 51829613 51829613 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 17 195 0 ENST00000371733.3:c.2284G>A p.Val762Ile p.V762I ENST00000371733 NM_001981.2 762 Gtc/Atc 0 +EPS15L1 UCSF GRCh37 19 16539545 16539545 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 9 89 0 ENST00000248070.6:c.526G>A p.Asp176Asn p.D176N ENST00000248070 NM_021235.2 176 Gat/Aat 0 +ERBB2 UCSF GRCh37 17 37883081 37883081 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 88 10 97 0 ENST00000269571.5:c.2984G>A p.Gly995Asp p.G995D ENST00000269571 995 gGc/gAc 0 +ERBB3 UCSF GRCh37 12 56489094 56489094 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 25 156 0 ENST00000267101.3:c.1913G>A p.Gly638Asp p.G638D ENST00000267101 NM_001982.3 638 gGc/gAc 0 +ERCC2 UCSF GRCh37 19 45872002 45872002 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 22 241 0 ENST00000391945.4:c.247-1G>A p.X83_splice ENST00000391945 NM_000400.3 0 +ERCC6L UCSF GRCh37 X 71427460 71427460 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 47 177 0 ENST00000334463.3:c.1157C>T p.Ser386Phe p.S386F ENST00000334463 NM_017669.2 386 tCt/tTt 0 +ERG UCSF GRCh37 21 39775600 39775600 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 23 176 1 ENST00000398919.2:c.441G>A p.Arg147= p.R147= ENST00000398919 NM_001243428.1 147 cgG/cgA 0 +ERN1 UCSF GRCh37 17 62130215 62130215 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 11 79 0 ENST00000433197.3:c.2178C>T p.Ser726= p.S726= ENST00000433197 NM_001433.3 726 agC/agT 0 +ESF1 UCSF GRCh37 20 13740436 13740438 + inframe_deletion In_Frame_Del DEL TTC TTC - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 0 ENST00000202816.1:c.1729_1731del p.Glu577del p.E577del ENST00000202816 NM_001276380.1 577 GAA/- 0 +ESPN UCSF GRCh37 1 6500850 6500850 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 5 20 0 ENST00000377828.1:c.840C>T p.Ala280= p.A280= ENST00000377828 NM_031475.2 280 gcC/gcT 0 +ESR1 UCSF GRCh37 6 152129195 152129195 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 75 553 0 ENST00000206249.3:c.148G>A p.Ala50Thr p.A50T ENST00000206249 NM_000125.3 50 Gcc/Acc 0 +ETV5 UCSF GRCh37 3 185797664 185797664 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 4 32 0 ENST00000306376.5:c.592C>T p.His198Tyr p.H198Y ENST00000306376 NM_004454.2 198 Cat/Tat 0 +EVPL UCSF GRCh37 17 74006574 74006574 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 23 231 0 ENST00000301607.3:c.2712C>T p.Ser904= p.S904= ENST00000301607 NM_001988.2 904 tcC/tcT 0 +EVX1 UCSF GRCh37 7 27285969 27285969 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 73 250 0 ENST00000496902.4:c.1149C>T p.Thr383= p.T383= ENST00000496902 383 acC/acT 0 +EXD2 UCSF GRCh37 14 69704378 69704378 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 238 41 338 0 ENST00000312994.5:c.1379C>T p.Thr460Ile p.T460I ENST00000312994 460 aCc/aTc 0 +EXOC5 UCSF GRCh37 14 57675449 57675449 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 10 69 0 ENST00000413566.2:c.2005G>A p.Asp669Asn p.D669N ENST00000413566 NM_006544.3 669 Gat/Aat 0 +EXOSC1 UCSF GRCh37 10 99200978 99200978 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 12 196 0 ENST00000370902.3:c.261C>T p.Ile87= p.I87= ENST00000370902 NM_016046.3 87 atC/atT 0 +EXOSC2 UCSF GRCh37 9 133570909 133570909 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 25 179 0 ENST00000372358.5:c.153G>A p.Lys51= p.K51= ENST00000372358 51 aaG/aaA 0 +F12 UCSF GRCh37 5 176829423 176829423 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 19 147 0 ENST00000253496.3:c.1718C>T p.Ala573Val p.A573V ENST00000253496 NM_000505.3 573 gCt/gTt 0 +F8 UCSF GRCh37 X 154132241 154132241 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 49 191 0 ENST00000360256.4:c.5938C>T p.His1980Tyr p.H1980Y ENST00000360256 NM_000132.3 1980 Cat/Tat 0 +F9 UCSF GRCh37 X 138644119 138644119 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 17 112 0 ENST00000218099.2:c.1275A>T p.Leu425Phe p.L425F ENST00000218099 NM_000133.3 425 ttA/ttT 0 +FAF2 UCSF GRCh37 5 175925919 175925919 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 20 102 0 ENST00000261942.6:c.844G>A p.Glu282Lys p.E282K ENST00000261942 NM_014613.2 282 Gaa/Aaa 0 +FAF2 UCSF GRCh37 5 175923506 175923506 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 22 190 0 ENST00000261942.6:c.681G>A p.Glu227= p.E227= ENST00000261942 NM_014613.2 227 gaG/gaA 0 +FAIM UCSF GRCh37 3 138340249 138340249 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 65 0 ENST00000393034.2:c.-22C>T p.X8_splice ENST00000393034 NM_018147.3 0 +FAM111B UCSF GRCh37 11 58892470 58892470 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 29 292 0 ENST00000343597.3:c.900G>A p.Gln300= p.Q300= ENST00000343597 NM_198947.3 300 caG/caA 0 +FAM120A UCSF GRCh37 9 96214591 96214591 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 23 142 0 ENST00000277165.6:c.394C>T p.Pro132Ser p.P132S ENST00000277165 NM_014612.3 132 Ccg/Tcg 0 +FAM123B UCSF GRCh37 X 63412254 63412254 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 32 152 0 ENST00000330258.3:c.913G>A p.Val305Met p.V305M ENST00000330258 NM_152424.3 305 Gtg/Atg 0 +FAM124A UCSF GRCh37 13 51854925 51854925 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 24 195 0 ENST00000322475.8:c.1174G>A p.Ala392Thr p.A392T ENST00000322475 NM_001242312.1 392 Gca/Aca 0 +FAM125B UCSF GRCh37 9 129102882 129102882 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 27 189 0 ENST00000361171.3:c.177G>A p.Arg59= p.R59= ENST00000361171 NM_033446.2 59 cgG/cgA 0 +FAM129B UCSF GRCh37 9 130270371 130270371 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 14 121 0 ENST00000373312.3:c.1542+1G>A p.X514_splice ENST00000373312 NM_022833.2 0 +FAM13A UCSF GRCh37 4 89658648 89658648 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 171 30 231 0 ENST00000264344.5:c.2621C>T p.Thr874Ile p.T874I ENST00000264344 NM_014883.3 874 aCt/aTt 0 +FAM13A UCSF GRCh37 4 89950686 89950686 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 20 136 0 ENST00000264344.5:c.142C>T p.Leu48Phe p.L48F ENST00000264344 NM_014883.3 48 Ctt/Ttt 0 +FAM150A UCSF GRCh37 8 53477802 53477802 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 7 30 0 ENST00000358543.4:c.15G>A p.Lys5= p.K5= ENST00000358543 NM_207413.3 5 aaG/aaA 0 +FAM159B UCSF GRCh37 5 63986544 63986544 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 19 139 0 ENST00000389074.5:c.94G>A p.Ala32Thr p.A32T ENST00000389074 NM_001164442.1 32 Gcg/Acg 0 +FAM161A UCSF GRCh37 2 62054254 62054254 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 27 255 0 ENST00000405894.3:c.1823C>T p.Thr608Ile p.T608I ENST00000405894 NM_032180.2 608 aCt/aTt 0 +FAM169A UCSF GRCh37 5 74137408 74137408 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 17 91 0 ENST00000389156.4:c.94C>T p.Pro32Ser p.P32S ENST00000389156 NM_015566.2 32 Cct/Tct 0 +FAM178B UCSF GRCh37 2 97637851 97637851 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 8 78 0 ENST00000417561.3:c.795C>T p.Phe265= p.F265= ENST00000417561 265 ttC/ttT 0 +FAM179B UCSF GRCh37 14 45478150 45478150 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 22 194 0 ENST00000361577.3:c.2939C>T p.Ala980Val p.A980V ENST00000361577 NM_015091.2 980 gCa/gTa 0 +FAM184A UCSF GRCh37 6 119345658 119345658 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 23 261 0 ENST00000338891.7:c.480G>A p.Glu160= p.E160= ENST00000338891 NM_024581.4 160 gaG/gaA 0 +FAM184B UCSF GRCh37 4 17654508 17654508 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 12 125 0 ENST00000265018.3:c.2136G>A p.Arg712= p.R712= ENST00000265018 NM_015688.1 712 agG/agA 0 +FAM193A UCSF GRCh37 4 2695364 2695364 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 230 40 336 1 ENST00000324666.5:c.1982C>T p.Ala661Val p.A661V ENST00000324666 NM_001256666.1 661 gCc/gTc 0 +FAM19A1 UCSF GRCh37 3 68466434 68466434 + synonymous_variant Silent SNP A A C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 9 29 0 ENST00000478136.1:c.123A>C p.Gly41= p.G41= ENST00000478136 NM_213609.3 41 ggA/ggC 0 +FAM20A UCSF GRCh37 17 66551789 66551789 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 13 113 0 ENST00000592554.1:c.500G>A p.Gly167Asp p.G167D ENST00000592554 NM_001243746.1 167 gGt/gAt 0 +FAM40A UCSF GRCh37 1 110582044 110582044 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 15 152 0 ENST00000369795.3:c.488C>T p.Ala163Val p.A163V ENST00000369795 NM_033088.3 163 gCa/gTa 0 +FAM69A UCSF GRCh37 1 93309726 93309726 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 25 154 0 ENST00000370310.4:c.501C>T p.Leu167= p.L167= ENST00000370310 NM_001006605.4 167 ctC/ctT 0 +FAM69B UCSF GRCh37 9 139617667 139617667 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 71 0 ENST00000371692.4:c.737C>T p.Pro246Leu p.P246L ENST00000371692 NM_152421.3 246 cCc/cTc 0 +FAM71E1 UCSF GRCh37 19 50979499 50979499 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 27 265 0 ENST00000600100.1:c.147C>T p.Leu49= p.L49= ENST00000600100 49 ctC/ctT 0 +FAM83G UCSF GRCh37 17 18874698 18874698 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 18 179 0 ENST00000345041.4:c.2446G>A p.Ala816Thr p.A816T ENST00000345041 816 Gcc/Acc 0 +FAM89A UCSF GRCh37 1 231175885 231175885 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 9 38 0 ENST00000366654.4:c.73C>T p.Pro25Ser p.P25S ENST00000366654 NM_198552.2 25 Ccc/Tcc 0 +FANCL UCSF GRCh37 2 58390002 58390002 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 34 0 ENST00000233741.4:c.902C>T p.Ser301Phe p.S301F ENST00000233741 NM_018062.3 301 tCt/tTt 0 +FAR2 UCSF GRCh37 12 29486702 29486702 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 16 168 0 ENST00000182377.4:c.1523G>A p.Arg508Lys p.R508K ENST00000182377 NM_018099.4 508 aGa/aAa 0 +FASN UCSF GRCh37 17 80037425 80037425 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 29 208 0 ENST00000306749.2:c.7206C>T p.Asp2402= p.D2402= ENST00000306749 NM_004104.4 2402 gaC/gaT 0 +FASTKD1 UCSF GRCh37 2 170393787 170393787 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 11 178 0 ENST00000453153.2:c.2138G>A p.Gly713Glu p.G713E ENST00000453153 NM_024622.4 713 gGa/gAa 0 +FAT1 UCSF GRCh37 4 187542680 187542680 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 20 235 0 ENST00000441802.2:c.5060G>A p.Gly1687Glu p.G1687E ENST00000441802 NM_005245.3 1687 gGg/gAg 0 +FAT2 UCSF GRCh37 5 150886790 150886790 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 254 37 380 0 ENST00000261800.5:c.12442C>T p.Leu4148Phe p.L4148F ENST00000261800 NM_001447.2 4148 Ctc/Ttc 0 +FAT2 UCSF GRCh37 5 150908849 150908849 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 15 64 0 ENST00000261800.5:c.9916A>G p.Thr3306Ala p.T3306A ENST00000261800 NM_001447.2 3306 Aca/Gca 0 +FAT3 UCSF GRCh37 11 92533914 92533914 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 8 61 0 ENST00000298047.6:c.7735G>A p.Gly2579Arg p.G2579R ENST00000298047 2579 Ggg/Agg 0 +FAT4 UCSF GRCh37 4 126355424 126355424 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 43 375 0 ENST00000394329.3:c.7043G>A p.Gly2348Glu p.G2348E ENST00000394329 NM_024582.4 2348 gGa/gAa 0 +FAT4 UCSF GRCh37 4 126241448 126241448 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 243 87 688 0 ENST00000394329.3:c.3882C>T p.Pro1294= p.P1294= ENST00000394329 NM_024582.4 1294 ccC/ccT 0 +FBN3 UCSF GRCh37 19 8174197 8174197 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 11 68 0 ENST00000270509.2:c.4532G>A p.Gly1511Glu p.G1511E ENST00000270509 NM_032447.3 1511 gGa/gAa 0 +FBP1 UCSF GRCh37 9 97372255 97372255 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 9 82 0 ENST00000375326.4:c.515C>T p.Thr172Ile p.T172I ENST00000375326 NM_000507.3 172 aCc/aTc 0 +FBXL14 UCSF GRCh37 12 1702849 1702849 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 57 124 0 ENST00000339235.3:c.384G>A p.Lys128= p.K128= ENST00000339235 NM_152441.2 128 aaG/aaA 0 +FBXL15 UCSF GRCh37 10 104181808 104181808 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 22 95 0 ENST00000224862.3:c.472C>T p.Leu158= p.L158= ENST00000224862 NM_024326.3 158 Ctg/Ttg 0 +FBXO24 UCSF GRCh37 7 100190601 100190601 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 10 43 0 ENST00000241071.6:c.754G>A p.Val252Ile p.V252I ENST00000241071 NM_033506.2 252 Gtt/Att 0 +FBXO38 UCSF GRCh37 5 147785859 147785859 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 39 379 0 ENST00000340253.5:c.770G>A p.Gly257Asp p.G257D ENST00000340253 NM_030793.4 257 gGc/gAc 0 +FBXO40 UCSF GRCh37 3 121340471 121340471 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 207 26 312 0 ENST00000338040.4:c.195C>T p.Cys65= p.C65= ENST00000338040 NM_016298.3 65 tgC/tgT 0 +FBXO41 UCSF GRCh37 2 73496421 73496421 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 11 97 0 ENST00000295133.5:c.521C>T p.Ala174Val p.A174V ENST00000295133 NM_001080410.2 174 gCt/gTt 0 +FBXO8 UCSF GRCh37 4 175158624 175158624 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 34 285 0 ENST00000393674.2:c.899G>A p.Ser300Asn p.S300N ENST00000393674 NM_012180.2 300 aGt/aAt 0 +FBXW11 UCSF GRCh37 5 171337700 171337700 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 17 148 0 ENST00000265094.5:c.249G>A p.Trp83Ter p.W83* ENST00000265094 NM_012300.2 83 tgG/tgA 0 +FBXW7 UCSF GRCh37 4 153303474 153303474 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 15 206 0 ENST00000281708.4:c.501+28981G>A *167* ENST00000281708 NM_033632.3 0 +FCGBP UCSF GRCh37 19 40362965 40362965 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 17 118 0 ENST00000221347.6:c.15105G>A p.Val5035= p.V5035= ENST00000221347 NM_003890.2 5035 gtG/gtA 0 +FDX1L UCSF GRCh37 19 10426655 10426655 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 30 232 0 ENST00000393708.3:c.18C>T p.Ala6= p.A6= ENST00000393708 NM_001031734.2 6 gcC/gcT 0 +FER1L5 UCSF GRCh37 2 97363883 97363883 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 14 169 0 ENST00000397978.2:n.657G>A *219* ENST00000397978 0 +FES UCSF GRCh37 15 91433429 91433429 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 10 96 0 ENST00000328850.3:c.1157C>T p.Thr386Ile p.T386I ENST00000328850 NM_002005.3 386 aCc/aTc 0 +FFAR1 UCSF GRCh37 19 35843297 35843297 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 10 100 0 ENST00000246553.2:c.843G>A p.Arg281= p.R281= ENST00000246553 NM_005303.2 281 agG/agA 0 +FGD2 UCSF GRCh37 6 36990014 36990014 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 15 124 0 ENST00000274963.8:c.1327-1G>A p.X443_splice ENST00000274963 NM_173558.3 0 +FGD4 UCSF GRCh37 12 32764155 32764155 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 26 187 0 ENST00000427716.2:c.1276G>A p.Glu426Lys p.E426K ENST00000427716 NM_139241.2 426 Gaa/Aaa 0 +FHAD1 UCSF GRCh37 1 15639596 15639596 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 12 80 0 ENST00000358897.4:c.1083G>A p.Glu361= p.E361= ENST00000358897 NM_052929.1 361 gaG/gaA 0 +FIGNL2 UCSF GRCh37 12 52214542 52214542 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 15 151 0 ENST00000564840.1:n.1658C>T *553* ENST00000564840 0 +FILIP1L UCSF GRCh37 3 99569857 99569857 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 34 365 0 ENST00000354552.3:c.663G>A p.Lys221= p.K221= ENST00000354552 NM_182909.2 221 aaG/aaA 0 +FIP1L1 UCSF GRCh37 4 54319155 54319155 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 14 105 0 ENST00000337488.6:c.1354G>A p.Asp452Asn p.D452N ENST00000337488 NM_030917.3 452 Gac/Aac 0 +FKBP15 UCSF GRCh37 9 115935780 115935780 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 12 152 0 ENST00000238256.3:c.2485G>A p.Ala829Thr p.A829T ENST00000238256 NM_015258.1 829 Gca/Aca 0 +FKBP5 UCSF GRCh37 6 35545001 35545001 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 21 191 0 ENST00000357266.4:c.1036C>T p.Leu346= p.L346= ENST00000357266 NM_004117.3 346 Ctg/Ttg 0 +FLG UCSF GRCh37 1 152286765 152286765 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 255 36 463 0 ENST00000368799.1:c.597G>A p.Arg199= p.R199= ENST00000368799 NM_002016.1 199 agG/agA 0 +FLG UCSF GRCh37 1 152280705 152280705 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 31 394 0 ENST00000368799.1:c.6657C>T p.Ser2219= p.S2219= ENST00000368799 NM_002016.1 2219 agC/agT 0 +FLJ22184 UCSF GRCh37 19 7934003 7934003 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 18 70 0 ENST00000539422.1:c.3957C>T p.Ile1319= p.I1319= ENST00000539422 NM_001190467.1 1319 atC/atT 0 +FLNB UCSF GRCh37 3 58092550 58092550 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 292 177 518 0 ENST00000295956.4:c.1891C>T p.Pro631Ser p.P631S ENST00000295956 NM_001457.3 631 Ccg/Tcg 0 +FLNC UCSF GRCh37 7 128478320 128478320 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 269 38 261 0 ENST00000325888.8:c.1048-1G>A p.X350_splice ENST00000325888 NM_001458.4 0 +FLT3LG UCSF GRCh37 19 49983661 49983661 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 13 100 0 ENST00000594009.1:c.588C>T p.Leu196= p.L196= ENST00000594009 NM_001204503.1 196 ctC/ctT 0 +FLVCR1 UCSF GRCh37 1 213032485 213032485 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 47 0 ENST00000366971.4:c.691C>T p.Pro231Ser p.P231S ENST00000366971 NM_014053.3 231 Ccc/Tcc 0 +FLYWCH1 UCSF GRCh37 16 2988390 2988390 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 23 167 0 ENST00000253928.9:c.1983C>T p.Asp661= p.D661= ENST00000253928 661 gaC/gaT 0 +FMO5 UCSF GRCh37 1 146673066 146673066 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 9 105 0 ENST00000254090.4:c.851C>T p.Thr284Ile p.T284I ENST00000254090 NM_001461.3 284 aCc/aTc 0 +FMOD UCSF GRCh37 1 203317066 203317066 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 16 108 0 ENST00000354955.4:c.333C>T p.Tyr111= p.Y111= ENST00000354955 NM_002023.4 111 taC/taT 0 +FNDC8 UCSF GRCh37 17 33454374 33454374 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 47 314 0 ENST00000158009.5:c.523G>A p.Val175Ile p.V175I ENST00000158009 NM_017559.2 175 Gtt/Att 0 +FOXC1 UCSF GRCh37 6 1610723 1610723 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 7 27 0 ENST00000380874.2:c.43G>A p.Val15Met p.V15M ENST00000380874 NM_001453.2 15 Gtg/Atg 0 +FOXE1 UCSF GRCh37 9 100616951 100616951 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 14 102 0 ENST00000375123.3:c.755C>T p.Ala252Val p.A252V ENST00000375123 NM_004473.3 252 gCc/gTc 0 +FOXM1 UCSF GRCh37 12 2983270 2983270 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 11 106 0 ENST00000359843.3:c.375C>T p.Thr125= p.T125= ENST00000359843 NM_021953.3 125 acC/acT 0 +FOXP1 UCSF GRCh37 3 71008464 71008464 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 328 55 478 0 ENST00000318789.4:c.1968C>T p.Asn656= p.N656= ENST00000318789 NM_032682.5 656 aaC/aaT 0 +FRAS1 UCSF GRCh37 4 79295343 79295343 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 5 43 0 ENST00000264895.6:c.3089C>T p.Ala1030Val p.A1030V ENST00000264895 NM_025074.6 1030 gCc/gTc 0 +FRAS1 UCSF GRCh37 4 79334210 79334210 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 12 128 0 ENST00000264895.6:c.4396G>A p.Val1466Met p.V1466M ENST00000264895 NM_025074.6 1466 Gtg/Atg 0 +FRAS1 UCSF GRCh37 4 79461764 79461764 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 13 100 0 ENST00000264895.6:c.11525G>A p.Arg3842His p.R3842H ENST00000264895 NM_025074.6 3842 cGc/cAc 0 +FRMD7 UCSF GRCh37 X 131212018 131212018 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 18 126 0 ENST00000298542.4:c.2027G>A p.Arg676Lys p.R676K ENST00000298542 NM_194277.2 676 aGa/aAa 0 +FRS3 UCSF GRCh37 6 41738438 41738438 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 32 184 0 ENST00000259748.2:c.1398G>A p.Met466Ile p.M466I ENST00000259748 466 atG/atA 0 +FSD2 UCSF GRCh37 15 83449004 83449004 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 7 39 0 ENST00000334574.8:c.982G>A p.Ala328Thr p.A328T ENST00000334574 328 Gct/Act 0 +FSIP1 UCSF GRCh37 15 39910257 39910257 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 16 266 0 ENST00000350221.3:c.1378G>A p.Val460Ile p.V460I ENST00000350221 NM_152597.4 460 Gtc/Atc 0 +FTSJ3 UCSF GRCh37 17 61903936 61903936 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 8 59 0 ENST00000427159.2:c.164C>T p.Pro55Leu p.P55L ENST00000427159 NM_017647.3 55 cCa/cTa 0 +FURIN UCSF GRCh37 15 91423126 91423126 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 13 119 0 ENST00000268171.3:c.1288G>A p.Asp430Asn p.D430N ENST00000268171 NM_002569.2 430 Gac/Aac 0 +FUT5 UCSF GRCh37 19 5867208 5867208 + missense_variant Missense_Mutation SNP C C T snp132_rs61731581 P24_Rec2 Untested WXS Illumina HiSeq 60 13 67 0 ENST00000252675.5:c.529G>A p.Asp177Asn p.D177N ENST00000252675 177 Gac/Aac 0 +FUT9 UCSF GRCh37 6 96651405 96651405 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 206 24 269 0 ENST00000302103.5:c.374G>A p.Arg125Lys p.R125K ENST00000302103 NM_006581.3 125 aGg/aAg 0 +FXN UCSF GRCh37 9 71668084 71668084 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 7 65 0 ENST00000377270.3:c.292C>T p.Leu98= p.L98= ENST00000377270 NM_000144.4 98 Cta/Tta 0 +FZD10 UCSF GRCh37 12 130648588 130648588 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 23 234 0 ENST00000229030.4:c.1101C>T p.Ile367= p.I367= ENST00000229030 367 atC/atT 0 +G3BP2 UCSF GRCh37 4 76571553 76571553 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 19 273 0 ENST00000359707.4:c.1145C>T p.Ser382Phe p.S382F ENST00000359707 NM_203505.2 382 tCt/tTt 0 +GABBR1 UCSF GRCh37 6 29599359 29599359 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 7 60 0 ENST00000377034.4:c.103C>T p.Pro35Ser p.P35S ENST00000377034 NM_001470.2 35 Ccg/Tcg 0 +GABRR1 UCSF GRCh37 6 89888600 89888600 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 206 33 272 0 ENST00000454853.2:c.1329C>T p.Ser443= p.S443= ENST00000454853 NM_001256704.1 443 agC/agT 0 +GALNT10 UCSF GRCh37 5 153570543 153570543 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 8 51 0 ENST00000297107.6:c.117C>T p.Thr39= p.T39= ENST00000297107 NM_198321.3 39 acC/acT 0 +GALNT5 UCSF GRCh37 2 158115992 158115992 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 10 94 0 ENST00000259056.4:c.1398C>T p.Val466= p.V466= ENST00000259056 NM_014568.1 466 gtC/gtT 0 +GALNT7 UCSF GRCh37 4 174169194 174169194 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 3 42 0 ENST00000265000.4:c.190G>A p.Asp64Asn p.D64N ENST00000265000 NM_017423.2 64 Gac/Aac 0 +GALNTL1 UCSF GRCh37 14 69814638 69814638 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 20 185 0 ENST00000337827.4:c.1458C>T p.Cys486= p.C486= ENST00000337827 NM_020692.2 486 tgC/tgT 0 +GALNTL2 UCSF GRCh37 3 16237308 16237308 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 9 20 0 ENST00000339732.5:c.581G>A p.Ser194Asn p.S194N ENST00000339732 NM_054110.4 194 aGc/aAc 0 +GANAB UCSF GRCh37 11 62402333 62402333 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 26 162 0 ENST00000356638.3:c.520G>A p.Gly174Arg p.G174R ENST00000356638 NM_198334.2 174 Gga/Aga 0 +GATA1 UCSF GRCh37 X 48650557 48650557 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 17 192 0 ENST00000376670.3:c.527C>T p.Thr176Ile p.T176I ENST00000376670 NM_002049.3 176 aCc/aTc 0 +GBAS UCSF GRCh37 7 56049253 56049253 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 4 38 0 ENST00000322090.3:c.366C>T p.Asp122= p.D122= ENST00000322090 NM_001483.2 122 gaC/gaT 0 +GBF1 UCSF GRCh37 10 104136322 104136322 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 50 378 0 ENST00000369983.3:c.4050G>A p.Gly1350= p.G1350= ENST00000369983 NM_004193.2 1350 ggG/ggA 0 +GCLC UCSF GRCh37 6 53372382 53372382 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 47 136 0 ENST00000229416.6:c.980C>T p.Ser327Phe p.S327F ENST00000229416 NM_001197115.1 327 tCc/tTc 0 +GCN1L1 UCSF GRCh37 12 120585002 120585002 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 39 112 0 ENST00000300648.6:c.4801G>A p.Asp1601Asn p.D1601N ENST00000300648 NM_006836.1 1601 Gac/Aac 0 +GCNT2 UCSF GRCh37 6 10586526 10586526 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 34 307 0 ENST00000379597.3:c.926-35058G>A *309* ENST00000379597 0 +GDAP1 UCSF GRCh37 8 75276411 75276411 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 24 214 0 ENST00000220822.7:c.886G>A p.Val296Ile p.V296I ENST00000220822 NM_001040875.2 296 Gtc/Atc 0 +GDPD4 UCSF GRCh37 11 76928350 76928350 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 18 199 0 ENST00000376217.2:c.1535G>A p.Ser512Asn p.S512N ENST00000376217 512 aGt/aAt 0 +GDPD4 UCSF GRCh37 11 76990369 76990369 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 9 65 0 ENST00000376217.2:c.129C>T p.Ala43= p.A43= ENST00000376217 43 gcC/gcT 0 +GDPD5 UCSF GRCh37 11 75154180 75154180 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 12 75 0 ENST00000336898.3:c.948+1G>A p.X316_splice ENST00000336898 NM_030792.6 0 +GFOD1 UCSF GRCh37 6 13487026 13487026 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 218 164 395 0 ENST00000379287.3:c.97G>A p.Gly33Ser p.G33S ENST00000379287 NM_018988.3 33 Ggc/Agc 0 +GGA1 UCSF GRCh37 22 38026166 38026166 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 7 53 0 ENST00000343632.4:c.1320G>A p.Gln440= p.Q440= ENST00000343632 NM_013365.4 440 caG/caA 0 +GGA3 UCSF GRCh37 17 73237757 73237757 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 21 194 0 ENST00000537686.1:c.*202G>A *68* ENST00000537686 0 +GGT7 UCSF GRCh37 20 33460541 33460541 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 5 43 0 ENST00000336431.5:c.78C>T p.Ser26= p.S26= ENST00000336431 NM_178026.2 26 agC/agT 0 +GHITM UCSF GRCh37 10 85901270 85901270 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 29 199 0 ENST00000372134.3:c.14G>A p.Arg5Lys p.R5K ENST00000372134 NM_014394.2 5 aGg/aAg 0 +GIGYF1 UCSF GRCh37 7 100285184 100285184 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 49 165 0 ENST00000275732.5:c.317G>A p.Gly106Glu p.G106E ENST00000275732 NM_022574.4 106 gGg/gAg 0 +GIGYF1 UCSF GRCh37 7 100285626 100285626 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 21 200 0 ENST00000275732.5:c.143C>T p.Ala48Val p.A48V ENST00000275732 NM_022574.4 48 gCt/gTt 0 +GIGYF1 UCSF GRCh37 7 100280392 100280392 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 13 79 0 ENST00000275732.5:c.2421G>A p.Gly807= p.G807= ENST00000275732 NM_022574.4 807 ggG/ggA 0 +GIPC2 UCSF GRCh37 1 78511943 78511943 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 10 51 0 ENST00000370759.3:c.165C>T p.Gly55= p.G55= ENST00000370759 NM_017655.4 55 ggC/ggT 0 +GJA9 UCSF GRCh37 1 39340326 39340326 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 22 242 0 ENST00000357771.3:c.1445G>A p.Gly482Glu p.G482E ENST00000357771 NM_030772.4 482 gGg/gAg 0 +GJC2 UCSF GRCh37 1 228345498 228345498 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 7 85 0 ENST00000366714.2:c.39G>A p.Leu13= p.L13= ENST00000366714 NM_020435.3 13 ctG/ctA 0 +GLA UCSF GRCh37 X 100653432 100653432 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 12 53 0 ENST00000218516.3:c.925G>A p.Ala309Thr p.A309T ENST00000218516 NM_000169.2 309 Gct/Act 0 +GLI1 UCSF GRCh37 12 57865572 57865572 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 802 108 171 0 ENST00000228682.2:c.3049G>A p.Gly1017Ser p.G1017S ENST00000228682 NM_005269.2 1017 Ggc/Agc 0 +GNA11 UCSF GRCh37 19 3121050 3121050 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 17 130 0 ENST00000078429.4:c.953C>T p.Pro318Leu p.P318L ENST00000078429 NM_002067.2 318 cCc/cTc 0 +GNA12 UCSF GRCh37 7 2834768 2834768 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 74 236 0 ENST00000275364.3:c.319G>A p.Val107Ile p.V107I ENST00000275364 NM_007353.2 107 Gtt/Att 0 +GNB2L1 UCSF GRCh37 5 180666492 180666492 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 20 137 0 ENST00000512805.1:c.520G>A p.Val174Ile p.V174I ENST00000512805 NM_006098.4 174 Gtc/Atc 0 +GNPDA2 UCSF GRCh37 4 44709880 44709880 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 32 307 0 ENST00000295448.3:c.658G>A p.Val220Ile p.V220I ENST00000295448 NM_138335.2 220 Gtc/Atc 0 +GNPTAB UCSF GRCh37 12 102163923 102163923 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 27 254 0 ENST00000299314.7:c.1160C>T p.Ala387Val p.A387V ENST00000299314 NM_024312.4 387 gCt/gTt 0 +GNPTG UCSF GRCh37 16 1411918 1411918 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 25 222 0 ENST00000204679.4:c.279G>A p.Glu93= p.E93= ENST00000204679 NM_032520.4 93 gaG/gaA 0 +GOLGA1 UCSF GRCh37 9 127693594 127693594 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 6 48 0 ENST00000373555.4:c.226+1G>A p.X76_splice ENST00000373555 NM_002077.3 0 +GOLGA2 UCSF GRCh37 9 131028282 131028282 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 29 0 ENST00000421699.2:c.618C>T p.His206= p.H206= ENST00000421699 NM_004486.4 206 caC/caT 0 +GOLGB1 UCSF GRCh37 3 121412909 121412909 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 406 190 771 0 ENST00000340645.5:c.6446G>A p.Arg2149His p.R2149H ENST00000340645 NM_001256487.1 2149 cGc/cAc 0 +GOLGB1 UCSF GRCh37 3 121386937 121386937 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 8 77 0 ENST00000340645.5:c.9375C>T p.Asp3125= p.D3125= ENST00000340645 NM_001256487.1 3125 gaC/gaT 0 +GPIHBP1 UCSF GRCh37 8 144296979 144296979 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 10 97 0 ENST00000330824.2:c.273C>T p.Thr91= p.T91= ENST00000330824 NM_178172.3 91 acC/acT 0 +GPR124 UCSF GRCh37 8 37691227 37691227 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 28 189 0 ENST00000412232.2:c.1318G>A p.Ala440Thr p.A440T ENST00000412232 NM_032777.9 440 Gcg/Acg 0 +GPR126 UCSF GRCh37 6 142741137 142741137 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 18 154 0 ENST00000230173.6:c.3215G>A p.Ser1072Asn p.S1072N ENST00000230173 NM_020455.5 1072 aGc/aAc 0 +GPR132 UCSF GRCh37 14 105518041 105518041 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 22 199 0 ENST00000329797.3:c.433G>A p.Val145Met p.V145M ENST00000329797 NM_013345.3 145 Gtg/Atg 0 +GPR143 UCSF GRCh37 X 9714171 9714171 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 52 0 ENST00000467482.1:c.571G>A p.Ala191Thr p.A191T ENST00000467482 191 Gcc/Acc 0 +GPR156 UCSF GRCh37 3 119905531 119905531 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 37 276 0 ENST00000315843.3:c.574C>T p.Leu192Phe p.L192F ENST00000315843 NM_153002.2 192 Ctc/Ttc 0 +GPR160 UCSF GRCh37 3 169801841 169801841 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 224 29 368 0 ENST00000355897.5:c.81G>A p.Leu27= p.L27= ENST00000355897 NM_014373.2 27 ctG/ctA 0 +GPR179 UCSF GRCh37 17 36482967 36482967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 468 90 649 0 ENST00000342292.4:c.6485C>T p.Pro2162Leu p.P2162L ENST00000342292 NM_001004334.2 2162 cCt/cTt 0 +GPR37L1 UCSF GRCh37 1 202097390 202097390 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 212 47 249 0 ENST00000367282.5:c.1152C>T p.Tyr384= p.Y384= ENST00000367282 NM_004767.3 384 taC/taT 0 +GPR50 UCSF GRCh37 X 150349701 150349701 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 49 231 0 ENST00000218316.3:c.1646C>T p.Ala549Val p.A549V ENST00000218316 NM_004224.3 549 gCc/gTc 0 +GPR77 UCSF GRCh37 19 47844575 47844575 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 27 226 0 ENST00000595464.1:c.519C>T p.Arg173= p.R173= ENST00000595464 NM_001271749.1 173 cgC/cgT 0 +GPR77 UCSF GRCh37 19 47844816 47844816 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 26 164 0 ENST00000595464.1:c.760C>T p.Leu254= p.L254= ENST00000595464 NM_001271749.1 254 Ctg/Ttg 0 +GPR98 UCSF GRCh37 5 89979842 89979842 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 27 228 0 ENST00000405460.2:c.6104C>T p.Thr2035Ile p.T2035I ENST00000405460 NM_032119.3 2035 aCt/aTt 0 +GPR98 UCSF GRCh37 5 90459629 90459629 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 23 212 0 ENST00000405460.2:c.18833C>T p.Ser6278Phe p.S6278F ENST00000405460 NM_032119.3 6278 tCt/tTt 0 +GPR98 UCSF GRCh37 5 89930943 89930943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 13 128 0 ENST00000405460.2:c.1852G>A p.Glu618Lys p.E618K ENST00000405460 NM_032119.3 618 Gag/Aag 0 +GPR98 UCSF GRCh37 5 89939622 89939622 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 32 111 0 ENST00000405460.2:c.2556G>A p.Leu852= p.L852= ENST00000405460 NM_032119.3 852 ttG/ttA 0 +GPRIN3 UCSF GRCh37 4 90168988 90168988 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 14 142 0 ENST00000333209.4:c.2274G>A p.Gln758= p.Q758= ENST00000333209 758 caG/caA 0 +GRAMD1B UCSF GRCh37 11 123479372 123479372 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 233 42 361 0 ENST00000529750.1:c.1090G>A p.Val364Ile p.V364I ENST00000529750 NM_020716.1 364 Gtc/Atc 0 +GRAMD1B UCSF GRCh37 11 123448180 123448180 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 34 271 0 ENST00000529750.1:c.129G>A p.Glu43= p.E43= ENST00000529750 NM_020716.1 43 gaG/gaA 0 +GRHPR UCSF GRCh37 9 37436728 37436728 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 7 94 0 ENST00000318158.6:c.936C>T p.Asn312= p.N312= ENST00000318158 NM_012203.1 312 aaC/aaT 0 +GRID1 UCSF GRCh37 10 87362214 87362214 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 15 99 0 ENST00000327946.7:c.2846G>A p.Ser949Asn p.S949N ENST00000327946 NM_017551.2 949 aGc/aAc 0 +GRIN2A UCSF GRCh37 16 9857613 9857613 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 24 241 0 ENST00000330684.3:c.3788G>A p.Gly1263Glu p.G1263E ENST00000330684 NM_001134407.1 1263 gGg/gAg 0 +GRIPAP1 UCSF GRCh37 X 48832511 48832511 + downstream_gene_variant 3'Flank SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 9 23 47 0 ENST00000376423 NM_207672.1 0 +GRK4 UCSF GRCh37 4 3029687 3029687 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 20 120 0 ENST00000398052.4:c.1019G>A p.Gly340Glu p.G340E ENST00000398052 NM_182982.2 340 gGa/gAa 0 +GRK4 UCSF GRCh37 4 3021409 3021409 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 32 227 0 ENST00000398052.4:c.783C>T p.Cys261= p.C261= ENST00000398052 NM_182982.2 261 tgC/tgT 0 +GRM2 UCSF GRCh37 3 51743012 51743012 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 6 63 0 ENST00000395052.3:c.13C>T p.Leu5Phe p.L5F ENST00000395052 NM_000839.3 5 Ctt/Ttt 0 +GRM7 UCSF GRCh37 3 6903548 6903548 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 64 203 0 ENST00000357716.4:c.473G>A p.Gly158Glu p.G158E ENST00000357716 NM_000844.3 158 gGg/gAg 0 +GRM7 UCSF GRCh37 3 7620195 7620195 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 211 25 280 0 ENST00000357716.4:c.1602G>A p.Lys534= p.K534= ENST00000357716 NM_000844.3 534 aaG/aaA 0 +GRM8 UCSF GRCh37 7 126086146 126086146 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 45 165 0 ENST00000339582.2:c.2677+34G>A *893* ENST00000339582 0 +GRSF1 UCSF GRCh37 4 71698972 71698972 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 16 124 0 ENST00000254799.6:c.533G>A p.Gly178Asp p.G178D ENST00000254799 NM_002092.3 178 gGt/gAt 0 +GSDMA UCSF GRCh37 17 38132196 38132196 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 27 251 0 ENST00000301659.4:c.1041G>A p.Gln347= p.Q347= ENST00000301659 NM_178171.4 347 caG/caA 0 +GSDMB UCSF GRCh37 17 38062477 38062477 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 277 35 374 0 ENST00000418519.1:c.775G>A p.Glu259Lys p.E259K ENST00000418519 NM_001165958.1 259 Gag/Aag 0 +GSG2 UCSF GRCh37 17 3628465 3628465 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 490 68 672 0 ENST00000325418.4:c.1236C>T p.Leu412= p.L412= ENST00000325418 NM_031965.2 412 ctC/ctT 0 +GSPT1 UCSF GRCh37 16 11981543 11981543 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 23 132 0 ENST00000420576.2:c.427G>A p.Gly143Ser p.G143S ENST00000420576 NM_001130007.1 143 Ggt/Agt 0 +GTF3C1 UCSF GRCh37 16 27500465 27500465 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 28 172 0 ENST00000356183.4:c.3328C>T p.Pro1110Ser p.P1110S ENST00000356183 NM_001520.3 1110 Cct/Tct 0 +GUCY1A2 UCSF GRCh37 11 106680975 106680975 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 234 41 325 0 ENST00000526355.2:c.1436C>T p.Thr479Ile p.T479I ENST00000526355 NM_000855.2 479 aCt/aTt 0 +GUCY2D UCSF GRCh37 17 7906839 7906839 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 10 22 0 ENST00000254854.4:c.474G>A p.Glu158= p.E158= ENST00000254854 NM_000180.3 158 gaG/gaA 0 +GUSB UCSF GRCh37 7 65441159 65441159 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 21 158 0 ENST00000304895.4:c.755G>A p.Gly252Asp p.G252D ENST00000304895 NM_000181.3 252 gGc/gAc 0 +H6PD UCSF GRCh37 1 9324292 9324292 + synonymous_variant Silent SNP G G A snp132_rs112516051 P24_Rec2 Untested WXS Illumina HiSeq 107 21 123 0 ENST00000377403.2:c.1740G>A p.Arg580= p.R580= ENST00000377403 NM_004285.3 580 cgG/cgA 0 +HACL1 UCSF GRCh37 3 15631079 15631079 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 5 70 0 ENST00000321169.5:c.349G>A p.Glu117Lys p.E117K ENST00000321169 NM_012260.2 117 Gaa/Aaa 0 +HCAR1 UCSF GRCh37 12 123214554 123214554 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 13 125 0 ENST00000432564.1:c.333G>A p.Ala111= p.A111= ENST00000432564 NM_032554.3 111 gcG/gcA 0 +HCN2 UCSF GRCh37 19 613904 613904 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 8 51 0 ENST00000251287.2:c.1878C>T p.Thr626= p.T626= ENST00000251287 NM_001194.3 626 acC/acT 0 +HCN3 UCSF GRCh37 1 155257939 155257939 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 18 143 0 ENST00000368358.3:c.2010C>T p.Arg670= p.R670= ENST00000368358 NM_020897.2 670 cgC/cgT 0 +HCST UCSF GRCh37 19 36394294 36394294 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 363 42 484 0 ENST00000246551.4:c.85C>T p.Pro29Ser p.P29S ENST00000246551 29 Cct/Tct 0 +HDAC1 UCSF GRCh37 1 32782331 32782331 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 136 24 159 0 ENST00000373548.3:c.228G>A p.Leu76= p.L76= ENST00000373548 NM_004964.2 76 ttG/ttA 0 +HDDC3 UCSF GRCh37 15 91475314 91475314 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 103 0 ENST00000394272.3:c.139G>A p.Ala47Thr p.A47T ENST00000394272 NM_001286451.1 47 Gcg/Acg 0 +HEATR4 UCSF GRCh37 14 73989011 73989011 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 9 98 0 ENST00000334988.2:c.846G>A p.Lys282= p.K282= ENST00000334988 NM_203309.2 282 aaG/aaA 0 +HEATR5B UCSF GRCh37 2 37215869 37215869 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 5 50 0 ENST00000233099.5:c.5831C>T p.Ala1944Val p.A1944V ENST00000233099 NM_019024.1 1944 gCc/gTc 0 +HECTD1 UCSF GRCh37 14 31576053 31576053 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 26 235 0 ENST00000399332.1:c.7025G>A p.Gly2342Glu p.G2342E ENST00000399332 NM_015382.2 2342 gGa/gAa 0 +HECTD1 UCSF GRCh37 14 31613428 31613428 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 25 263 0 ENST00000399332.1:c.2667G>A p.Met889Ile p.M889I ENST00000399332 NM_015382.2 889 atG/atA 0 +HECTD1 UCSF GRCh37 14 31576304 31576304 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 11 161 0 ENST00000399332.1:c.6774C>T p.Asp2258= p.D2258= ENST00000399332 NM_015382.2 2258 gaC/gaT 0 +HECW1 UCSF GRCh37 7 43483838 43483838 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 16 120 0 ENST00000395891.2:c.1067G>A p.Ser356Asn p.S356N ENST00000395891 NM_015052.3 356 aGt/aAt 0 +HELT UCSF GRCh37 4 185941579 185941579 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 10 135 0 ENST00000515777.1:c.382C>T p.Leu128= p.L128= ENST00000515777 128 Ctg/Ttg 0 +HELZ UCSF GRCh37 17 65104735 65104735 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 20 141 0 ENST00000358691.5:c.4597C>T p.Pro1533Ser p.P1533S ENST00000358691 NM_014877.3 1533 Cca/Tca 0 +HENMT1 UCSF GRCh37 1 109192907 109192910 + frameshift_variant Frame_Shift_Del DEL TTCC TTCC - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 0 ENST00000370032.5:c.679_682del p.Gly227SerfsTer55 p.G227Sfs*55 ENST00000370032 NM_144584.2 227 GGAAtc/tc 0 +HEPACAM UCSF GRCh37 11 124794649 124794649 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 36 240 0 ENST00000298251.4:c.402G>A p.Glu134= p.E134= ENST00000298251 NM_152722.4 134 gaG/gaA 0 +HEPH UCSF GRCh37 X 65414964 65414964 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 3 22 0 ENST00000343002.2:c.1394G>A p.Gly465Asp p.G465D ENST00000343002 465 gGt/gAt 0 +HEPHL1 UCSF GRCh37 11 93797501 93797501 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 11 91 0 ENST00000315765.9:c.633C>T p.Ile211= p.I211= ENST00000315765 NM_001098672.1 211 atC/atT 0 +HERC1 UCSF GRCh37 15 63922732 63922732 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 392 55 511 0 ENST00000443617.2:c.12899C>T p.Ala4300Val p.A4300V ENST00000443617 NM_003922.3 4300 gCt/gTt 0 +HERC2 UCSF GRCh37 15 28436142 28436142 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 75 0 ENST00000261609.7:c.8618C>T p.Thr2873Ile p.T2873I ENST00000261609 NM_004667.5 2873 aCc/aTc 0 +HERC2 UCSF GRCh37 15 28386941 28386941 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 234 32 333 0 ENST00000261609.7:c.11752C>T p.Leu3918= p.L3918= ENST00000261609 NM_004667.5 3918 Ctg/Ttg 0 +HERC5 UCSF GRCh37 4 89389506 89389506 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 7 76 0 ENST00000264350.3:c.1067C>T p.Thr356Ile p.T356I ENST00000264350 NM_016323.3 356 aCc/aTc 0 +HFE2 UCSF GRCh37 1 145416933 145416933 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 311 55 453 0 ENST00000336751.5:c.1278G>A p.Gln426= p.Q426= ENST00000336751 NM_213653.3 426 caG/caA 0 +HGFAC UCSF GRCh37 4 3449664 3449664 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 4 60 0 ENST00000382774.3:c.1538G>A p.Arg513His p.R513H ENST00000382774 NM_001528.2 513 cGc/cAc 0 +HIC2 UCSF GRCh37 22 21799854 21799854 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 8 73 0 ENST00000407464.2:c.670G>A p.Glu224Lys p.E224K ENST00000407464 NM_015094.2 224 Gag/Aag 0 +HIP1 UCSF GRCh37 7 75176264 75176264 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 63 0 ENST00000336926.6:c.2532C>T p.Leu844= p.L844= ENST00000336926 NM_005338.6 844 ctC/ctT 0 +HIST1H2AK UCSF GRCh37 6 27805862 27805862 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 12 104 0 ENST00000330180.2:c.256C>T p.Leu86= p.L86= ENST00000330180 NM_003510.2 86 Ctg/Ttg 0 +HIST1H2BK UCSF GRCh37 6 27114231 27114231 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 11 98 0 ENST00000356950.1:c.347C>T p.Thr116Ile p.T116I ENST00000356950 116 aCc/aTc 0 +HJURP UCSF GRCh37 2 234750741 234750741 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 28 294 0 ENST00000411486.2:c.685C>T p.Pro229Ser p.P229S ENST00000411486 NM_018410.3 229 Cct/Tct 0 +HMCN1 UCSF GRCh37 1 186039746 186039746 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 25 254 0 ENST00000271588.4:c.7996C>T p.Pro2666Ser p.P2666S ENST00000271588 NM_031935.2 2666 Cca/Tca 0 +HMCN1 UCSF GRCh37 1 186107095 186107095 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 4 37 0 ENST00000271588.4:c.13915C>T p.Pro4639Ser p.P4639S ENST00000271588 NM_031935.2 4639 Cct/Tct 0 +HMMR UCSF GRCh37 5 162896656 162896656 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 13 89 0 ENST00000358715.3:c.280C>T p.Leu94Phe p.L94F ENST00000358715 94 Ctt/Ttt 0 +HNRNPU UCSF GRCh37 1 245021421 245021421 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 222 31 271 0 ENST00000283179.9:c.1386G>A p.Lys462= p.K462= ENST00000283179 462 aaG/aaA 0 +HNRNPUL1 UCSF GRCh37 19 41774156 41774156 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 58 0 ENST00000392006.3:c.324C>T p.Asn108= p.N108= ENST00000392006 NM_007040.3 108 aaC/aaT 0 +HOGA1 UCSF GRCh37 10 99358621 99358621 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 9 116 0 ENST00000370646.4:c.301C>T p.Pro101Ser p.P101S ENST00000370646 NM_138413.3 101 Ccc/Tcc 0 +HOXA11 UCSF GRCh37 7 27224318 27224318 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 28 120 0 ENST00000006015.3:c.446G>A p.Gly149Asp p.G149D ENST00000006015 NM_005523.5 149 gGc/gAc 0 +HOXB1 UCSF GRCh37 17 46608212 46608212 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 8 91 0 ENST00000239174.6:c.55C>T p.Pro19Ser p.P19S ENST00000239174 NM_002144.3 19 Ccc/Tcc 0 +HOXB2 UCSF GRCh37 17 46622042 46622042 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 8 42 0 ENST00000330070.4:c.232C>T p.Leu78= p.L78= ENST00000330070 NM_002145.3 78 Ctg/Ttg 0 +HOXB8 UCSF GRCh37 17 46691826 46691826 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 24 220 0 ENST00000239144.4:c.241G>A p.Asp81Asn p.D81N ENST00000239144 NM_024016.3 81 Gac/Aac 0 +HOXC12 UCSF GRCh37 12 54350237 54350237 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 11 62 0 ENST00000243103.3:c.736G>A p.Glu246Lys p.E246K ENST00000243103 NM_173860.1 246 Gaa/Aaa 0 +HOXC8 UCSF GRCh37 12 54403386 54403389 + frameshift_variant Frame_Shift_Del DEL GAGC GAGC AAG NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 0 ENST00000040584.4:c.318_321delinsAAG p.Ser107ArgfsTer23 p.S107Rfs*23 ENST00000040584 NM_022658.3 106 gcGAGC/gcAAG 0 +HOXD9 UCSF GRCh37 2 176987832 176987832 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 7 86 0 ENST00000249499.6:c.336C>T p.Pro112= p.P112= ENST00000249499 NM_014213.3 112 ccC/ccT 0 +HPCA UCSF GRCh37 1 33359382 33359382 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 161 31 226 0 ENST00000373467.3:c.501G>A p.Glu167= p.E167= ENST00000373467 NM_002143.2 167 gaG/gaA 0 +HPS4 UCSF GRCh37 22 26864578 26864578 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 18 115 0 ENST00000336873.5:c.608C>T p.Thr203Ile p.T203I ENST00000336873 203 aCc/aTc 0 +HPS4 UCSF GRCh37 22 26860252 26860252 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 27 149 0 ENST00000336873.5:c.1344C>T p.Gly448= p.G448= ENST00000336873 448 ggC/ggT 0 +HR UCSF GRCh37 8 21978318 21978318 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 22 158 0 ENST00000381418.4:c.2521C>T p.Pro841Ser p.P841S ENST00000381418 NM_005144.4 841 Ccc/Tcc 0 +HRC UCSF GRCh37 19 49656929 49656929 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 332 57 505 0 ENST00000252825.4:c.1566G>A p.Glu522= p.E522= ENST00000252825 NM_002152.2 522 gaG/gaA 0 +HRH2 UCSF GRCh37 5 175110611 175110611 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 423 74 627 0 ENST00000231683.2:c.375G>A p.Arg125= p.R125= ENST00000231683 NM_022304.2 125 cgG/cgA 0 +HRNR UCSF GRCh37 1 152191458 152191458 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 13 131 0 ENST00000368801.2:c.2647C>T p.His883Tyr p.H883Y ENST00000368801 NM_001009931.2 883 Cat/Tat 0 +HSD3B1 UCSF GRCh37 1 120056648 120056648 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 9 113 0 ENST00000369413.3:c.502G>A p.Ala168Thr p.A168T ENST00000369413 168 Gcg/Acg 0 +HSD3B2 UCSF GRCh37 1 119964551 119964551 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 7 73 0 ENST00000369416.3:c.427G>A p.Glu143Lys p.E143K ENST00000369416 NM_000198.3 143 Gaa/Aaa 0 +HSPA9 UCSF GRCh37 5 137895578 137895578 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 12 103 0 ENST00000297185.3:c.1385C>T p.Thr462Ile p.T462I ENST00000297185 NM_004134.6 462 aCc/aTc 0 +HSPB3 UCSF GRCh37 5 53751797 53751797 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 22 219 0 ENST00000302005.1:c.178G>A p.Ala60Thr p.A60T ENST00000302005 NM_006308.2 60 Gca/Aca 0 +HSPB9 UCSF GRCh37 17 40275126 40275126 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 19 141 0 ENST00000355067.3:c.258C>T p.Asp86= p.D86= ENST00000355067 NM_033194.2 86 gaC/gaT 0 +HSPB9 UCSF GRCh37 17 40275195 40275195 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 248 45 311 0 ENST00000355067.3:c.327C>T p.Asn109= p.N109= ENST00000355067 NM_033194.2 109 aaC/aaT 0 +HTRA3 UCSF GRCh37 4 8304200 8304200 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 21 223 0 ENST00000307358.2:c.1062G>A p.Lys354= p.K354= ENST00000307358 NM_053044.3 354 aaG/aaA 0 +HYAL2 UCSF GRCh37 3 50357515 50357515 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 70 169 0 ENST00000357750.4:c.406G>A p.Asp136Asn p.D136N ENST00000357750 NM_003773.4 136 Gac/Aac 0 +HYDIN UCSF GRCh37 16 70841568 70841568 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 35 138 0 ENST00000393567.2:c.15281C>T p.Thr5094Ile p.T5094I ENST00000393567 NM_001270974.1 5094 aCc/aTc 0 +HYI UCSF GRCh37 1 43917481 43917481 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 16 143 0 ENST00000372425.4:c.543C>T p.Leu181= p.L181= ENST00000372425 181 ctC/ctT 0 +IARS UCSF GRCh37 9 95009661 95009661 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 38 221 0 ENST00000375643.3:c.2789C>T p.Thr930Ile p.T930I ENST00000375643 NM_013417.3 930 aCt/aTt 0 +IBTK UCSF GRCh37 6 82936964 82936964 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 33 332 0 ENST00000306270.7:c.599C>T p.Thr200Ile p.T200I ENST00000306270 NM_015525.2 200 aCc/aTc 0 +ICA1L UCSF GRCh37 2 203644301 203644301 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 12 155 0 ENST00000358299.2:c.1404C>T p.Asn468= p.N468= ENST00000358299 468 aaC/aaT 0 +ID2 UCSF GRCh37 2 8822431 8822431 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 28 234 0 ENST00000234091.4:c.136C>T p.Leu46Phe p.L46F ENST00000234091 46 Ctc/Ttc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 9 8 28 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IER5 UCSF GRCh37 1 181058475 181058475 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 13 35 0 ENST00000367577.4:c.437G>A p.Gly146Glu p.G146E ENST00000367577 NM_016545.4 146 gGg/gAg 0 +IER5L UCSF GRCh37 9 131940255 131940255 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 14 131 0 ENST00000372491.2:c.77G>A p.Gly26Asp p.G26D ENST00000372491 NM_203434.2 26 gGc/gAc 0 +IFFO1 UCSF GRCh37 12 6660128 6660128 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 11 61 0 ENST00000396840.2:c.813C>T p.Asp271= p.D271= ENST00000396840 271 gaC/gaT 0 +IFIT2 UCSF GRCh37 10 91066329 91066329 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 36 338 0 ENST00000371826.3:c.616C>T p.Pro206Ser p.P206S ENST00000371826 NM_001547.4 206 Cct/Tct 0 +IFITM2 UCSF GRCh37 11 308246 308246 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 8 40 0 ENST00000399817.4:c.54C>T p.Asn18= p.N18= ENST00000399817 NM_006435.2 18 aaC/aaT 0 +IFITM3 UCSF GRCh37 11 319894 319894 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 18 203 0 ENST00000399808.4:c.346C>T p.Leu116Phe p.L116F ENST00000399808 NM_021034.2 116 Ctc/Ttc 0 +IFNA8 UCSF GRCh37 9 21409203 21409203 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 25 292 0 ENST00000380205.1:c.28G>A p.Ala10Thr p.A10T ENST00000380205 NM_002170.3 10 Gcc/Acc 0 +IFNAR2 UCSF GRCh37 21 34635415 34635415 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 58 197 0 ENST00000342136.4:c.1158G>A p.Gln386= p.Q386= ENST00000342136 386 caG/caA 0 +IFT80 UCSF GRCh37 3 159976317 159976317 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 18 139 0 ENST00000326448.7:c.2330C>T p.Pro777Leu p.P777L ENST00000326448 NM_020800.2 777 cCc/cTc 0 +IGF1R UCSF GRCh37 15 99465622 99465622 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 32 235 0 ENST00000268035.6:c.2447G>A p.Ser816Asn p.S816N ENST00000268035 NM_000875.3 816 aGc/aAc 0 +IGF2R UCSF GRCh37 6 160485892 160485892 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 39 257 0 ENST00000356956.1:c.4074G>A p.Gln1358= p.Q1358= ENST00000356956 NM_000876.2 1358 caG/caA 0 +IGFBP1 UCSF GRCh37 7 45928394 45928394 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 5 45 0 ENST00000275525.3:c.143G>A p.Cys48Tyr p.C48Y ENST00000275525 NM_000596.2 48 tGc/tAc 0 +IGLON5 UCSF GRCh37 19 51830417 51830417 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 15 147 0 ENST00000270642.8:c.730C>T p.Pro244Ser p.P244S ENST00000270642 NM_001101372.1 244 Ccc/Tcc 0 +IGSF3 UCSF GRCh37 1 117122089 117122089 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 14 145 0 ENST00000369486.3:c.3259C>T p.Pro1087Ser p.P1087S ENST00000369486 NM_001007237.2 1087 Ccc/Tcc 0 +IKBKB UCSF GRCh37 8 42129684 42129684 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 22 140 0 ENST00000520810.1:c.66G>A p.Gly22= p.G22= ENST00000520810 NM_001556.2 22 ggG/ggA 0 +IL17RB UCSF GRCh37 3 53890927 53890927 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 24 202 0 ENST00000288167.3:c.586G>A p.Val196Met p.V196M ENST00000288167 NM_018725.3 196 Gtg/Atg 0 +IL17RE UCSF GRCh37 3 9956252 9956252 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 29 214 0 ENST00000383814.3:c.1317G>A p.Gln439= p.Q439= ENST00000383814 NM_153480.1 439 caG/caA 0 +IL18 UCSF GRCh37 11 112025712 112025712 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.00273,snp132_rs61734549 P24_Rec2 Untested WXS Illumina HiSeq 90 38 171 0 ENST00000280357.7:c.65C>T p.Thr22Met p.T22M ENST00000280357 NM_001562.3 22 aCg/aTg 0 +IL1RAP UCSF GRCh37 3 190326923 190326923 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 11 139 0 ENST00000072516.3:c.490G>A p.Asp164Asn p.D164N ENST00000072516 NM_001167929.1 164 Gat/Aat 0 +IL1RAP UCSF GRCh37 3 190345117 190345117 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 11 138 0 ENST00000072516.3:c.781G>A p.Glu261Lys p.E261K ENST00000072516 NM_001167929.1 261 Gag/Aag 0 +IL20RB UCSF GRCh37 3 136710829 136710829 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 10 94 0 ENST00000329582.4:c.581C>T p.Thr194Ile p.T194I ENST00000329582 NM_144717.3 194 aCc/aTc 0 +IL21 UCSF GRCh37 4 123542065 123542065 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 80 290 0 ENST00000264497.3:c.102C>T p.Arg34= p.R34= ENST00000264497 NM_021803.3 34 cgC/cgT 0 +IL4R UCSF GRCh37 16 27353453 27353453 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 55 168 0 ENST00000395762.2:c.82G>A p.Val28Ile p.V28I ENST00000395762 NM_000418.3 28 Gtc/Atc 0 +IL4R UCSF GRCh37 16 27351507 27351507 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 30 71 0 ENST00000395762.2:c.-18G>A p.X6_splice ENST00000395762 NM_000418.3 0 +IMMP2L UCSF GRCh37 7 110303686 110303686 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 25 238 0 ENST00000331762.3:c.500G>A p.Arg167His p.R167H ENST00000331762 NM_001244606.1 167 cGc/cAc 0 +INADL UCSF GRCh37 1 62293175 62293175 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 13 48 0 ENST00000371158.2:c.1900G>A p.Val634Ile p.V634I ENST00000371158 NM_176877.2 634 Gtt/Att 0 +INO80D UCSF GRCh37 2 206874416 206874416 + stop_gained Nonsense_Mutation SNP T T A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 12 65 0 ENST00000403263.1:c.1645A>T p.Lys549Ter p.K549* ENST00000403263 NM_017759.4 549 Aag/Tag 0 +INPP1 UCSF GRCh37 2 191224847 191224847 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 11 34 0 ENST00000322522.4:c.19G>A p.Glu7Lys p.E7K ENST00000322522 NM_002194.3 7 Gag/Aag 0 +INPP5J UCSF GRCh37 22 31529913 31529913 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 19 133 0 ENST00000331075.5:c.2529C>T p.Ser843= p.S843= ENST00000331075 NM_001284285.1 843 tcC/tcT 0 +INTS1 UCSF GRCh37 7 1517564 1517564 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 10 5 24 0 ENST00000404767.3:c.4639G>A p.Gly1547Arg p.G1547R ENST00000404767 NM_001080453.2 1547 Ggg/Agg 0 +INTS12 UCSF GRCh37 4 106613132 106613132 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 12 121 0 ENST00000340139.5:c.657+1G>A p.X219_splice ENST00000340139 NM_020395.3 0 +INTS3 UCSF GRCh37 1 153737438 153737438 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 272 43 324 0 ENST00000318967.2:c.1989G>A p.Gln663= p.Q663= ENST00000318967 NM_023015.3 663 caG/caA 0 +INTS6 UCSF GRCh37 13 51952403 51952403 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 6 65 0 ENST00000311234.4:c.1574C>T p.Thr525Ile p.T525I ENST00000311234 NM_012141.2 525 aCt/aTt 0 +INTS9 UCSF GRCh37 8 28635391 28635391 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 13 132 0 ENST00000521022.1:c.1350C>T p.Thr450= p.T450= ENST00000521022 NM_018250.3 450 acC/acT 0 +IPO13 UCSF GRCh37 1 44415262 44415262 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 217 25 291 0 ENST00000372343.3:c.258C>T p.Ile86= p.I86= ENST00000372343 NM_014652.3 86 atC/atT 0 +IQCG UCSF GRCh37 3 197665484 197665484 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 24 343 0 ENST00000265239.6:c.450C>T p.Val150= p.V150= ENST00000265239 NM_032263.3 150 gtC/gtT 0 +IQCH UCSF GRCh37 15 67713652 67713652 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 10 101 0 ENST00000335894.4:c.2242C>T p.Pro748Ser p.P748S ENST00000335894 NM_001031715.2 748 Cct/Tct 0 +IQGAP1 UCSF GRCh37 15 90997763 90997763 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 11 129 0 ENST00000268182.5:c.1591G>A p.Val531Met p.V531M ENST00000268182 NM_003870.3 531 Gtg/Atg 0 +IQGAP1 UCSF GRCh37 15 91035809 91035809 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 8 106 0 ENST00000268182.5:c.4494G>A p.Arg1498= p.R1498= ENST00000268182 NM_003870.3 1498 agG/agA 0 +IQGAP3 UCSF GRCh37 1 156524122 156524122 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 13 91 0 ENST00000361170.2:c.1353C>T p.Asn451= p.N451= ENST00000361170 NM_178229.4 451 aaC/aaT 0 +IQSEC2 UCSF GRCh37 X 53350028 53350028 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 57 170 0 ENST00000396435.3:c.294C>T p.His98= p.H98= ENST00000396435 NM_001111125.2 98 caC/caT 0 +IRAK2 UCSF GRCh37 3 10280464 10280464 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 18 171 0 ENST00000256458.4:c.1506G>A p.Arg502= p.R502= ENST00000256458 NM_001570.3 502 cgG/cgA 0 +IRF5 UCSF GRCh37 7 128587398 128587398 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 16 79 0 ENST00000249375.4:c.548C>T p.Thr183Ile p.T183I ENST00000249375 NM_032643.3 183 aCt/aTt 0 +IRS2 UCSF GRCh37 13 110436746 110436746 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 32 230 0 ENST00000375856.3:c.1655G>A p.Cys552Tyr p.C552Y ENST00000375856 NM_003749.2 552 tGt/tAt 0 +ISLR2 UCSF GRCh37 15 74425298 74425298 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 16 123 0 ENST00000361742.3:c.203G>A p.Arg68His p.R68H ENST00000361742 NM_001130136.1 68 cGc/cAc 0 +ISM1 UCSF GRCh37 20 13251391 13251391 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 175 26 249 0 ENST00000262487.4:c.378+1G>A p.X126_splice ENST00000262487 NM_080826.1 0 +ITFG1 UCSF GRCh37 16 47494809 47494809 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 144 25 172 0 ENST00000320640.6:c.148C>T p.Leu50Phe p.L50F ENST00000320640 NM_030790.3 50 Ctt/Ttt 0 +ITGA11 UCSF GRCh37 15 68612657 68612657 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 13 104 0 ENST00000315757.7:c.2482G>A p.Val828Ile p.V828I ENST00000315757 NM_001004439.1 828 Gtc/Atc 0 +ITGAL UCSF GRCh37 16 30492887 30492887 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 25 206 0 ENST00000356798.6:c.704G>A p.Gly235Asp p.G235D ENST00000356798 NM_002209.2 235 gGt/gAt 0 +ITGAL UCSF GRCh37 16 30532967 30532967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 5 33 0 ENST00000356798.6:c.3494G>A p.Ser1165Asn p.S1165N ENST00000356798 NM_002209.2 1165 aGt/aAt 0 +ITGAX UCSF GRCh37 16 31382817 31382817 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 34 351 1 ENST00000268296.4:c.2004C>T p.Ser668= p.S668= ENST00000268296 NM_000887.3 668 agC/agT 0 +ITIH3 UCSF GRCh37 3 52836799 52836799 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 16 99 0 ENST00000449956.2:c.1686C>T p.Thr562= p.T562= ENST00000449956 NM_002217.3 562 acC/acT 0 +ITPKB UCSF GRCh37 1 226924158 226924158 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 27 191 0 ENST00000272117.3:c.1002G>A p.Glu334= p.E334= ENST00000272117 334 gaG/gaA 0 +ITPR1 UCSF GRCh37 3 4699885 4699885 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 43 347 1 ENST00000354582.6:c.1074G>A p.Val358= p.V358= ENST00000354582 358 gtG/gtA 0 +ITPR2 UCSF GRCh37 12 26748513 26748513 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 5 95 0 ENST00000381340.3:c.4265C>T p.Ala1422Val p.A1422V ENST00000381340 NM_002223.2 1422 gCt/gTt 0 +ITPRIPL2 UCSF GRCh37 16 19126795 19126795 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 15 131 0 ENST00000381440.3:c.1012C>T p.Pro338Ser p.P338S ENST00000381440 NM_001034841.3 338 Cct/Tct 0 +ITSN1 UCSF GRCh37 21 35140087 35140087 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 17 192 0 ENST00000381318.3:c.997C>T p.Pro333Ser p.P333S ENST00000381318 NM_003024.2 333 Cca/Tca 0 +ITSN2 UCSF GRCh37 2 24432863 24432863 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 7 89 0 ENST00000355123.4:c.4297C>T p.Arg1433Trp p.R1433W ENST00000355123 NM_006277.2 1433 Cgg/Tgg 0 +ITSN2 UCSF GRCh37 2 24433813 24433813 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 42 0 ENST00000355123.4:c.4093C>T p.Leu1365= p.L1365= ENST00000355123 NM_006277.2 1365 Ctg/Ttg 0 +IWS1 UCSF GRCh37 2 128250901 128250901 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 12 102 0 ENST00000295321.4:c.1885C>T p.Pro629Ser p.P629S ENST00000295321 NM_017969.2 629 Cct/Tct 0 +JAG2 UCSF GRCh37 14 105609197 105609197 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 34 212 0 ENST00000331782.3:c.3552C>T p.Gly1184= p.G1184= ENST00000331782 NM_002226.4 1184 ggC/ggT 0 +JAKMIP1 UCSF GRCh37 4 6107536 6107536 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 33 244 0 ENST00000282924.5:c.288G>A p.Glu96= p.E96= ENST00000282924 NM_144720.3 96 gaG/gaA 0 +JAM2 UCSF GRCh37 21 27078290 27078290 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 49 176 0 ENST00000480456.1:c.698-1G>A p.X233_splice ENST00000480456 NM_001270407.1 0 +JMJD7-PLA2G4B UCSF GRCh37 15 42139646 42139646 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 258 47 390 0 ENST00000382448.4:c.2752C>T p.Pro918Ser p.P918S ENST00000382448 918 Ccc/Tcc 0 +KALRN UCSF GRCh37 3 124303687 124303687 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 6 45 0 ENST00000291478.5:c.19G>A p.Ala7Thr p.A7T ENST00000291478 NM_007064.3 7 Gct/Act 0 +KATNAL1 UCSF GRCh37 13 30804647 30804647 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 17 175 0 ENST00000380615.3:c.970G>A p.Ala324Thr p.A324T ENST00000380615 NM_032116.4 324 Gca/Aca 0 +KAZN UCSF GRCh37 1 15287323 15287323 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 6 29 0 ENST00000376030.2:c.370C>T p.Leu124= p.L124= ENST00000376030 NM_201628.2 124 Ctg/Ttg 0 +KBTBD12 UCSF GRCh37 3 127642929 127642929 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 7 115 0 ENST00000405109.1:c.1025C>T p.Ala342Val p.A342V ENST00000405109 342 gCc/gTc 0 +KBTBD7 UCSF GRCh37 13 41768322 41768322 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 262 45 331 0 ENST00000379483.3:c.72G>A p.Arg24= p.R24= ENST00000379483 NM_032138.4 24 agG/agA 0 +KBTBD8 UCSF GRCh37 3 67058550 67058550 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 43 152 0 ENST00000417314.2:c.1547C>T p.Pro516Leu p.P516L ENST00000417314 516 cCa/cTa 0 +KCNA10 UCSF GRCh37 1 111060543 111060543 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 25 155 0 ENST00000369771.2:c.867G>A p.Arg289= p.R289= ENST00000369771 NM_005549.2 289 cgG/cgA 0 +KCNA4 UCSF GRCh37 11 30033372 30033372 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 28 202 0 ENST00000328224.6:c.854C>T p.Pro285Leu p.P285L ENST00000328224 NM_002233.3 285 cCc/cTc 0 +KCNAB1 UCSF GRCh37 3 156009754 156009754 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 18 218 0 ENST00000490337.1:c.276-129651C>T *92* ENST00000490337 NM_172160.2 0 +KCNH6 UCSF GRCh37 17 61615962 61615962 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 13 118 0 ENST00000583023.1:c.1893C>T p.Leu631= p.L631= ENST00000583023 NM_030779.3 631 ctC/ctT 0 +KCNH6 UCSF GRCh37 17 61613308 61613308 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 45 331 0 ENST00000583023.1:c.1380G>A p.Gln460= p.Q460= ENST00000583023 NM_030779.3 460 caG/caA 0 +KCNK16 UCSF GRCh37 6 39290301 39290301 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 28 0 ENST00000373229.5:c.16C>T p.Leu6Phe p.L6F ENST00000373229 NM_032115.3 6 Ctc/Ttc 0 +KCNK4 UCSF GRCh37 11 64060554 64060554 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 13 66 0 ENST00000394525.2:c.64C>T p.Leu22= p.L22= ENST00000394525 22 Ctg/Ttg 0 +KCNK6 UCSF GRCh37 19 38817562 38817562 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 405 74 524 0 ENST00000263372.3:c.652G>A p.Gly218Ser p.G218S ENST00000263372 NM_004823.1 218 Ggc/Agc 0 +KCNN2 UCSF GRCh37 5 113740307 113740307 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 24 231 0 ENST00000264773.3:c.755C>T p.Ala252Val p.A252V ENST00000264773 NM_001278204.1 252 gCt/gTt 0 +KCNQ4 UCSF GRCh37 1 41304096 41304096 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 373 58 483 0 ENST00000347132.5:c.1989C>T p.Asp663= p.D663= ENST00000347132 NM_004700.3 663 gaC/gaT 0 +KCNS2 UCSF GRCh37 8 99441166 99441166 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 27 227 0 ENST00000287042.4:c.959C>T p.Ala320Val p.A320V ENST00000287042 NM_020697.2 320 gCc/gTc 0 +KCNU1 UCSF GRCh37 8 36666241 36666241 + stop_gained Nonsense_Mutation SNP C C A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 50 179 0 ENST00000399881.3:c.662C>A p.Ser221Ter p.S221* ENST00000399881 NM_001031836.2 221 tCa/tAa 0 +KCTD18 UCSF GRCh37 2 201357981 201357981 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 25 215 0 ENST00000359878.3:c.678G>A p.Arg226= p.R226= ENST00000359878 NM_152387.2 226 cgG/cgA 0 +KCTD8 UCSF GRCh37 4 44449706 44449706 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 17 185 0 ENST00000360029.3:c.835G>A p.Ala279Thr p.A279T ENST00000360029 NM_198353.2 279 Gcc/Acc 0 +KCTD8 UCSF GRCh37 4 44449677 44449677 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 20 168 0 ENST00000360029.3:c.864C>T p.Phe288= p.F288= ENST00000360029 NM_198353.2 288 ttC/ttT 0 +KDELR1 UCSF GRCh37 19 48893746 48893746 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 15 166 0 ENST00000330720.2:c.127G>A p.Val43Met p.V43M ENST00000330720 NM_006801.2 43 Gtg/Atg 0 +KDELR3 UCSF GRCh37 22 38875687 38875687 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 68 245 0 ENST00000216014.4:c.282C>T p.Arg94= p.R94= ENST00000216014 NM_006855.3 94 cgC/cgT 0 +KDM1B UCSF GRCh37 6 18215319 18215319 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 11 74 1 ENST00000297792.5:c.1495C>T p.Gln499Ter p.Q499* ENST00000297792 499 Cag/Tag 0 +KDM2B UCSF GRCh37 12 122013723 122013723 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 49 156 0 ENST00000377071.4:c.313C>T p.Pro105Ser p.P105S ENST00000377071 NM_032590.4 105 Ccc/Tcc 0 +KDM3A UCSF GRCh37 2 86693750 86693750 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 29 258 0 ENST00000312912.5:c.1263G>A p.Lys421= p.K421= ENST00000312912 NM_018433.5 421 aaG/aaA 0 +KDM5B UCSF GRCh37 1 202715307 202715307 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 30 245 0 ENST00000367265.3:c.2161G>A p.Glu721Lys p.E721K ENST00000367265 NM_006618.3 721 Gaa/Aaa 0 +KDM5C UCSF GRCh37 X 53222430 53222430 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 25 143 0 ENST00000375401.3:c.4402G>A p.Glu1468Lys p.E1468K ENST00000375401 NM_004187.3 1468 Gag/Aag 0 +KIAA0247 UCSF GRCh37 14 70170146 70170146 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 12 82 0 ENST00000342745.4:c.156C>T p.Gly52= p.G52= ENST00000342745 NM_014734.3 52 ggC/ggT 0 +KIAA0284 UCSF GRCh37 14 105349562 105349562 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 13 143 0 ENST00000414716.3:c.768G>A p.Gly256= p.G256= ENST00000414716 NM_001112726.2 256 ggG/ggA 0 +KIAA0408 UCSF GRCh37 6 127767619 127767619 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 380 65 624 0 ENST00000483725.3:c.1845G>A p.Gln615= p.Q615= ENST00000483725 NM_014702.4 615 caG/caA 0 +KIAA0556 UCSF GRCh37 16 27763144 27763144 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 16 181 0 ENST00000261588.4:c.3451G>A p.Asp1151Asn p.D1151N ENST00000261588 NM_015202.2 1151 Gac/Aac 0 +KIAA0664 UCSF GRCh37 17 2607704 2607704 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 397 57 593 0 ENST00000435359.1:c.141C>T p.Gly47= p.G47= ENST00000435359 NM_015229.3 47 ggC/ggT 0 +KIAA0889 UCSF GRCh37 20 35422950 35422950 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 20 205 0 ENST00000237536.4:c.3535C>T p.Pro1179Ser p.P1179S ENST00000237536 NM_080627.2 1179 Cct/Tct 0 +KIAA0889 UCSF GRCh37 20 35422834 35422834 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 27 158 0 ENST00000237536.4:c.3651C>T p.Leu1217= p.L1217= ENST00000237536 NM_080627.2 1217 ctC/ctT 0 +KIAA1009 UCSF GRCh37 6 84862339 84862339 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 18 166 0 ENST00000403245.3:c.3554G>A p.Gly1185Glu p.G1185E ENST00000403245 NM_014895.2 1185 gGa/gAa 0 +KIAA1009 UCSF GRCh37 6 84836120 84836120 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 357 69 574 0 ENST00000403245.3:c.3982C>T p.Gln1328Ter p.Q1328* ENST00000403245 NM_014895.2 1328 Caa/Taa 0 +KIAA1033 UCSF GRCh37 12 105520060 105520060 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 14 139 0 ENST00000332180.5:c.958G>A p.Gly320Arg p.G320R ENST00000332180 NM_015275.1 320 Gga/Aga 0 +KIAA1109 UCSF GRCh37 4 123160789 123160789 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 22 261 0 ENST00000264501.4:c.3952C>T p.Leu1318Phe p.L1318F ENST00000264501 1318 Ctt/Ttt 0 +KIAA1109 UCSF GRCh37 4 123161284 123161284 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 246 42 417 0 ENST00000264501.4:c.4447G>A p.Glu1483Lys p.E1483K ENST00000264501 1483 Gaa/Aaa 0 +KIAA1109 UCSF GRCh37 4 123185567 123185567 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 40 178 0 ENST00000264501.4:c.7302G>A p.Gln2434= p.Q2434= ENST00000264501 2434 caG/caA 0 +KIAA1217 UCSF GRCh37 10 24790376 24790376 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 15 123 0 ENST00000376454.3:c.1903C>T p.Pro635Ser p.P635S ENST00000376454 NM_019590.3 635 Cca/Tca 0 +KIAA1217 UCSF GRCh37 10 24833394 24833394 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 439 58 333 0 ENST00000376454.3:c.5195C>T p.Pro1732Leu p.P1732L ENST00000376454 NM_019590.3 1732 cCt/cTt 0 +KIAA1217 UCSF GRCh37 10 24809110 24809110 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 27 78 0 ENST00000376454.3:c.2236G>A p.Val746Ile p.V746I ENST00000376454 NM_019590.3 746 Gtt/Att 0 +KIAA1239 UCSF GRCh37 4 37440706 37440706 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 30 246 0 ENST00000309447.5:c.990C>T p.Tyr330= p.Y330= ENST00000309447 NM_001144990.1 330 taC/taT 0 +KIAA1239 UCSF GRCh37 4 37445900 37445900 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 21 197 0 ENST00000309447.5:c.2290C>T p.Leu764= p.L764= ENST00000309447 NM_001144990.1 764 Ctg/Ttg 0 +KIAA1239 UCSF GRCh37 4 37440478 37440478 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 16 138 0 ENST00000309447.5:c.762G>A p.Lys254= p.K254= ENST00000309447 NM_001144990.1 254 aaG/aaA 0 +KIAA1244 UCSF GRCh37 6 138576629 138576629 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 309 50 474 0 ENST00000251691.4:c.827C>T p.Thr276Ile p.T276I ENST00000251691 NM_020340.4 276 aCc/aTc 0 +KIAA1274 UCSF GRCh37 10 72285826 72285826 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 14 89 0 ENST00000263563.6:c.119G>A p.Ser40Asn p.S40N ENST00000263563 NM_014431.2 40 aGc/aAc 0 +KIAA1383 UCSF GRCh37 1 232943021 232943021 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 17 256 0 ENST00000418460.1:c.2252G>A p.Arg751Lys p.R751K ENST00000418460 NM_019090.2 751 aGa/aAa 0 +KIAA1432 UCSF GRCh37 9 5772967 5772967 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 15 151 0 ENST00000414202.2:c.3870C>T p.Ser1290= p.S1290= ENST00000414202 NM_001206557.1 1290 tcC/tcT 0 +KIAA1522 UCSF GRCh37 1 33207765 33207765 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 3 23 0 ENST00000401073.2:c.210C>T p.Ala70= p.A70= ENST00000401073 NM_020888.2 70 gcC/gcT 0 +KIAA1671 UCSF GRCh37 22 25581079 25581079 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 8 58 0 ENST00000358431.3:c.5335G>A p.Asp1779Asn p.D1779N ENST00000358431 NM_001145206.1 1779 Gat/Aat 0 +KIAA1683 UCSF GRCh37 19 18376086 18376086 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 24 123 0 ENST00000600328.3:c.2264G>A p.Cys755Tyr p.C755Y ENST00000600328 755 tGc/tAc 0 +KIAA1731 UCSF GRCh37 11 93402014 93402014 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 57 0 ENST00000325212.6:c.350G>A p.Arg117Lys p.R117K ENST00000325212 117 aGg/aAg 0 +KIAA1797 UCSF GRCh37 9 20789539 20789539 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 6 109 0 ENST00000338382.6:c.1387G>A p.Asp463Asn p.D463N ENST00000338382 463 Gac/Aac 0 +KIAA1797 UCSF GRCh37 9 20720401 20720401 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 17 166 0 ENST00000338382.6:c.155G>A p.Trp52Ter p.W52* ENST00000338382 52 tGg/tAg 0 +KIAA1984 UCSF GRCh37 9 139694861 139694861 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 196 27 292 0 ENST00000338005.6:c.459C>T p.Asn153= p.N153= ENST00000338005 NM_001039374.4 153 aaC/aaT 0 +KIAA2026 UCSF GRCh37 9 6007765 6007765 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 49 124 0 ENST00000399933.3:c.23G>A p.Gly8Glu p.G8E ENST00000399933 NM_001017969.2 8 gGa/gAa 0 +KIF13A UCSF GRCh37 6 17785781 17785781 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 34 326 0 ENST00000259711.6:c.3453C>T p.Ala1151= p.A1151= ENST00000259711 NM_022113.5 1151 gcC/gcT 0 +KIF14 UCSF GRCh37 1 200559261 200559261 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 12 98 0 ENST00000367350.4:c.2953G>A p.Ala985Thr p.A985T ENST00000367350 NM_014875.2 985 Gca/Aca 0 +KIF16B UCSF GRCh37 20 16359469 16359469 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 43 0 ENST00000354981.2:c.3178C>T p.Leu1060= p.L1060= ENST00000354981 NM_024704.4 1060 Ctg/Ttg 0 +KIF18B UCSF GRCh37 17 43011932 43011932 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 62 223 0 ENST00000593135.1:c.630C>T p.Arg210= p.R210= ENST00000593135 NM_001265577.1 210 cgC/cgT 0 +KIF1A UCSF GRCh37 2 241660422 241660422 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 12 98 0 ENST00000320389.7:c.4474C>T p.Pro1492Ser p.P1492S ENST00000320389 NM_004321.6 1492 Ccg/Tcg 0 +KIF1A UCSF GRCh37 2 241685214 241685214 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 67 0 ENST00000320389.7:c.3012G>A p.Val1004= p.V1004= ENST00000320389 NM_004321.6 1004 gtG/gtA 0 +KIF20B UCSF GRCh37 10 91478491 91478491 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 24 290 0 ENST00000371728.3:c.1296G>A p.Arg432= p.R432= ENST00000371728 NM_001284259.1 432 cgG/cgA 0 +KIF21B UCSF GRCh37 1 200978397 200978397 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 23 122 0 ENST00000422435.2:c.261G>A p.Gly87= p.G87= ENST00000422435 NM_001252100.1 87 ggG/ggA 0 +KIF26A UCSF GRCh37 14 104640048 104640048 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 6 38 0 ENST00000423312.2:c.1873G>A p.Gly625Arg p.G625R ENST00000423312 NM_015656.1 625 Gga/Aga 0 +KIRREL UCSF GRCh37 1 158064889 158064889 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 287 53 329 0 ENST00000359209.6:c.2253G>A p.Gln751= p.Q751= ENST00000359209 751 caG/caA 0 +KLF1 UCSF GRCh37 19 12997911 12997911 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 8 56 0 ENST00000264834.4:c.44C>T p.Thr15Ile p.T15I ENST00000264834 NM_006563.3 15 aCc/aTc 0 +KLF16 UCSF GRCh37 19 1863116 1863116 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 3 51 0 ENST00000250916.4:c.381C>T p.His127= p.H127= ENST00000250916 NM_031918.3 127 caC/caT 0 +KLF9 UCSF GRCh37 9 73002854 73002854 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 14 105 0 ENST00000377126.2:c.573C>T p.Thr191= p.T191= ENST00000377126 NM_001206.2 191 acC/acT 0 +KLHDC7A UCSF GRCh37 1 18807887 18807887 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 16 137 0 ENST00000400664.1:c.412C>T p.Pro138Ser p.P138S ENST00000400664 NM_152375.2 138 Cct/Tct 0 +KLHDC9 UCSF GRCh37 1 161068684 161068684 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 13 121 0 ENST00000368011.4:c.359G>A p.Trp120Ter p.W120* ENST00000368011 NM_152366.4 120 tGg/tAg 0 +KLHL1 UCSF GRCh37 13 70293505 70293505 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 16 160 0 ENST00000377844.4:c.2011G>A p.Glu671Lys p.E671K ENST00000377844 NM_020866.2 671 Gaa/Aaa 0 +KLHL15 UCSF GRCh37 X 24006440 24006440 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 161 63 247 0 ENST00000328046.8:c.1413G>A p.Lys471= p.K471= ENST00000328046 NM_030624.2 471 aaG/aaA 0 +KLHL29 UCSF GRCh37 2 23919339 23919339 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 5 54 0 ENST00000486442.1:c.2061C>T p.Thr687= p.T687= ENST00000486442 NM_052920.1 687 acC/acT 0 +KLHL30 UCSF GRCh37 2 239057685 239057685 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 57 169 0 ENST00000409223.1:c.1377G>A p.Lys459= p.K459= ENST00000409223 459 aaG/aaA 0 +KLHL4 UCSF GRCh37 X 86921482 86921482 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 13 4 34 0 ENST00000373119.4:c.2105C>T p.Pro702Leu p.P702L ENST00000373119 NM_019117.4 702 cCt/cTt 0 +KLK14 UCSF GRCh37 19 51581312 51581312 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 16 141 0 ENST00000156499.2:c.756C>T p.Asn252= p.N252= ENST00000156499 252 aaC/aaT 0 +KLK9 UCSF GRCh37 19 51509714 51509714 + missense_variant,splice_region_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 24 0 ENST00000250366.6:c.466G>A p.Ala156Thr p.A156T ENST00000250366 NM_012315.1 156 Gcg/Acg 0 +KLRAQ1 UCSF GRCh37 2 48737178 48737178 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 13 108 0 ENST00000294952.8:c.2110G>A p.Ala704Thr p.A704T ENST00000294952 NM_001135629.2 704 Gcc/Acc 0 +KNTC1 UCSF GRCh37 12 123099634 123099634 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 45 321 0 ENST00000333479.7:c.5973+1G>A p.X1991_splice ENST00000333479 NM_014708.4 0 +KPNB1 UCSF GRCh37 17 45755444 45755444 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 177 28 227 0 ENST00000290158.4:c.2136G>A p.Gln712= p.Q712= ENST00000290158 NM_002265.5 712 caG/caA 0 +KRBA1 UCSF GRCh37 7 149422489 149422489 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 24 189 0 ENST00000319551.8:c.1210C>T p.Leu404= p.L404= ENST00000319551 404 Ctg/Ttg 0 +KREMEN2 UCSF GRCh37 16 3017392 3017392 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 7 28 0 ENST00000303746.5:c.1045G>A p.Gly349Arg p.G349R ENST00000303746 349 Ggg/Agg 0 +KREMEN2 UCSF GRCh37 16 3017388 3017388 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 3 24 0 ENST00000303746.5:c.1041C>T p.Leu347= p.L347= ENST00000303746 347 ctC/ctT 0 +KRT26 UCSF GRCh37 17 38928333 38928333 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 22 194 0 ENST00000335552.4:c.33G>A p.Arg11= p.R11= ENST00000335552 NM_181539.4 11 agG/agA 0 +KRT36 UCSF GRCh37 17 39642793 39642793 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 4 36 0 ENST00000328119.6:c.1239C>T p.Cys413= p.C413= ENST00000328119 NM_003771.4 413 tgC/tgT 0 +KRT38 UCSF GRCh37 17 39596854 39596854 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 21 231 0 ENST00000246646.3:c.320C>T p.Thr107Ile p.T107I ENST00000246646 NM_006771.3 107 aCc/aTc 0 +KRT74 UCSF GRCh37 12 52967372 52967372 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 23 136 0 ENST00000305620.2:c.190G>A p.Ala64Thr p.A64T ENST00000305620 NM_175053.3 64 Gct/Act 0 +KRT76 UCSF GRCh37 12 53165733 53165733 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 23 232 0 ENST00000332411.2:c.1185G>A p.Arg395= p.R395= ENST00000332411 NM_015848.4 395 agG/agA 0 +KRT84 UCSF GRCh37 12 52771896 52771896 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 4 38 1 ENST00000257951.3:c.1725C>T p.Gly575= p.G575= ENST00000257951 NM_033045.3 575 ggC/ggT 0 +KRTAP13-2 UCSF GRCh37 21 31744248 31744248 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 22 212 0 ENST00000399889.2:c.284C>T p.Thr95Ile p.T95I ENST00000399889 NM_181621.3 95 aCt/aTt 0 +KRTAP4-11 UCSF GRCh37 17 39274332 39274332 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 11 23 0 ENST00000391413.2:c.236G>A p.Cys79Tyr p.C79Y ENST00000391413 NM_033059.3 79 tGc/tAc 0 +KY UCSF GRCh37 3 134369669 134369669 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 12 101 0 ENST00000423778.2:c.134G>A p.Gly45Glu p.G45E ENST00000423778 NM_178554.4 45 gGa/gAa 0 +L3MBTL1 UCSF GRCh37 20 42169455 42169455 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 42 336 0 ENST00000427442.2:c.2328G>A p.Glu776= p.E776= ENST00000427442 776 gaG/gaA 0 +L3MBTL3 UCSF GRCh37 6 130370449 130370449 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 242 31 350 0 ENST00000361794.2:c.125C>T p.Ala42Val p.A42V ENST00000361794 NM_032438.2 42 gCc/gTc 0 +LAMA3 UCSF GRCh37 18 21481116 21481116 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 5 32 0 ENST00000313654.9:c.6030G>A p.Gln2010= p.Q2010= ENST00000313654 NM_198129.1 2010 caG/caA 0 +LAMA4 UCSF GRCh37 6 112438987 112438987 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 8 99 0 ENST00000230538.7:c.4936G>A p.Glu1646Lys p.E1646K ENST00000230538 NM_001105206.2 1646 Gaa/Aaa 0 +LAMB1 UCSF GRCh37 7 107603473 107603473 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 7 90 0 ENST00000222399.6:c.1734C>T p.Asp578= p.D578= ENST00000222399 NM_002291.2 578 gaC/gaT 0 +LAMB2 UCSF GRCh37 3 49161261 49161261 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 24 198 0 ENST00000305544.4:c.3697C>T p.His1233Tyr p.H1233Y ENST00000305544 1233 Cac/Tac 0 +LAMB4 UCSF GRCh37 7 107704388 107704388 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 10 77 0 ENST00000205386.4:c.2879C>T p.Pro960Leu p.P960L ENST00000205386 960 cCa/cTa 0 +LAMC2 UCSF GRCh37 1 183197619 183197619 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 16 144 0 ENST00000264144.4:c.1579G>A p.Ala527Thr p.A527T ENST00000264144 NM_005562.2 527 Gcc/Acc 0 +LAMP3 UCSF GRCh37 3 182871876 182871876 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 11 91 0 ENST00000265598.3:c.353C>T p.Pro118Leu p.P118L ENST00000265598 NM_014398.3 118 cCt/cTt 0 +LARGE UCSF GRCh37 22 33712154 33712154 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 3 32 0 ENST00000354992.2:c.1368C>T p.Thr456= p.T456= ENST00000354992 NM_004737.4 456 acC/acT 0 +LARS2 UCSF GRCh37 3 45436039 45436039 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 58 0 ENST00000265537.3:c.94G>A p.Val32Ile p.V32I ENST00000265537 NM_015340.3 32 Gta/Ata 0 +LAT UCSF GRCh37 16 28997983 28997983 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 94 223 0 ENST00000360872.5:c.433G>A p.Ala145Thr p.A145T ENST00000360872 145 Gcc/Acc 0 +LATS1 UCSF GRCh37 6 150004816 150004816 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 28 194 0 ENST00000253339.5:c.1409G>A p.Gly470Glu p.G470E ENST00000253339 470 gGa/gAa 0 +LATS2 UCSF GRCh37 13 21563229 21563229 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 10 87 0 ENST00000382592.4:c.690C>T p.His230= p.H230= ENST00000382592 NM_014572.2 230 caC/caT 0 +LBR UCSF GRCh37 1 225600175 225600175 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 4 30 0 ENST00000272163.4:c.1065C>T p.Asp355= p.D355= ENST00000272163 NM_002296.3 355 gaC/gaT 0 +LCA5L UCSF GRCh37 21 40778481 40778481 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 214 31 364 0 ENST00000288350.3:c.1340G>A p.Arg447Lys p.R447K ENST00000288350 447 aGa/aAa 0 +LCK UCSF GRCh37 1 32751172 32751172 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 4 32 0 ENST00000336890.5:c.1385C>T p.Pro462Leu p.P462L ENST00000336890 NM_005356.3 462 cCt/cTt 0 +LCMT2 UCSF GRCh37 15 43621541 43621541 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 288 57 428 0 ENST00000305641.5:c.1147C>T p.His383Tyr p.H383Y ENST00000305641 NM_014793.4 383 Cac/Tac 0 +LENG8 UCSF GRCh37 19 54966627 54966627 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 12 47 0 ENST00000326764.5:c.906C>T p.Thr302= p.T302= ENST00000326764 NM_052925.2 302 acC/acT 0 +LEPREL1 UCSF GRCh37 3 189688682 189688682 + splice_acceptor_variant Splice_Site SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 40 134 0 ENST00000319332.5:c.1818-2A>G p.X606_splice ENST00000319332 NM_018192.3 0 +LEPREL1 UCSF GRCh37 3 189713109 189713109 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 7 40 0 ENST00000319332.5:c.603G>A p.Gln201= p.Q201= ENST00000319332 NM_018192.3 201 caG/caA 0 +LEPREL2 UCSF GRCh37 12 6937907 6937907 + upstream_gene_variant 5'Flank SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 5 22 0 ENST00000290510 0 +LEPREL4 UCSF GRCh37 17 39968144 39968144 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 19 137 0 ENST00000355468.3:c.24G>A p.Leu8= p.L8= ENST00000355468 8 ctG/ctA 0 +LGALS12 UCSF GRCh37 11 63276249 63276249 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 217 37 284 0 ENST00000394618.3:c.225-1G>A p.X75_splice ENST00000394618 NM_033101.3 0 +LGALS2 UCSF GRCh37 22 37966674 37966674 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 22 246 0 ENST00000215886.4:c.158C>T p.Ser53Phe p.S53F ENST00000215886 NM_006498.2 53 tCc/tTc 0 +LGALS3BP UCSF GRCh37 17 76969137 76969137 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 25 218 0 ENST00000262776.3:c.544G>A p.Ala182Thr p.A182T ENST00000262776 NM_005567.3 182 Gcc/Acc 0 +LGALS3BP UCSF GRCh37 17 76968372 76968372 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 27 213 0 ENST00000262776.3:c.1044C>T p.Phe348= p.F348= ENST00000262776 NM_005567.3 348 ttC/ttT 0 +LGALS8 UCSF GRCh37 1 236706260 236706260 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 27 264 0 ENST00000341872.6:c.549+173G>A *183* ENST00000341872 NM_201543.2 0 +LGR5 UCSF GRCh37 12 71977498 71977498 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 394 71 546 0 ENST00000266674.5:c.1708C>T p.Leu570= p.L570= ENST00000266674 NM_001277226.1 570 Ctg/Ttg 0 +LGSN UCSF GRCh37 6 63990557 63990557 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 23 243 0 ENST00000370657.4:c.899C>T p.Ala300Val p.A300V ENST00000370657 300 gCc/gTc 0 +LHCGR UCSF GRCh37 2 48958435 48958435 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 14 156 0 ENST00000294954.7:c.164C>T p.Ser55Leu p.S55L ENST00000294954 NM_000233.3 55 tCa/tTa 0 +LHX8 UCSF GRCh37 1 75602876 75602876 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 263 44 359 0 ENST00000294638.5:c.197C>T p.Ser66Phe p.S66F ENST00000294638 NM_001001933.1 66 tCc/tTc 0 +LIFR UCSF GRCh37 5 38481941 38481941 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 27 292 0 ENST00000263409.4:c.3050C>T p.Ala1017Val p.A1017V ENST00000263409 NM_002310.5 1017 gCt/gTt 0 +LILRB2 UCSF GRCh37 19 54781751 54781751 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 9 82 0 ENST00000391749.4:c.1301C>T p.Ser434Phe p.S434F ENST00000391749 NM_001278406.1 434 tCc/tTc 0 +LIMA1 UCSF GRCh37 12 50616006 50616006 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 59 148 0 ENST00000341247.4:c.428C>T p.Pro143Leu p.P143L ENST00000341247 NM_016357.4 143 cCc/cTc 0 +LIMK1 UCSF GRCh37 7 73513509 73513509 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 21 206 0 ENST00000336180.2:c.549C>T p.Asp183= p.D183= ENST00000336180 NM_002314.3 183 gaC/gaT 0 +LIMS2 UCSF GRCh37 2 128400530 128400530 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 5 49 0 ENST00000355119.4:c.477C>T p.Tyr159= p.Y159= ENST00000355119 NM_001161403.1 159 taC/taT 0 +LIN7C UCSF GRCh37 11 27520323 27520323 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 15 143 0 ENST00000278193.2:c.467C>T p.Ala156Val p.A156V ENST00000278193 NM_018362.3 156 gCt/gTt 0 +LLGL2 UCSF GRCh37 17 73567161 73567161 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 17 186 0 ENST00000392550.3:c.2156C>T p.Ala719Val p.A719V ENST00000392550 NM_001031803.1 719 gCt/gTt 0 +LMO7 UCSF GRCh37 13 76395518 76395518 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 28 248 0 ENST00000465261.2:c.1714G>A p.Val572Ile p.V572I ENST00000465261 NM_015842.2 572 Gta/Ata 0 +LMOD1 UCSF GRCh37 1 201868704 201868704 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 46 390 0 ENST00000367288.4:c.1437G>A p.Leu479= p.L479= ENST00000367288 NM_012134.2 479 ctG/ctA 0 +LMTK2 UCSF GRCh37 7 97821000 97821000 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 15 95 0 ENST00000297293.5:c.1223C>T p.Thr408Ile p.T408I ENST00000297293 NM_014916.3 408 aCt/aTt 0 +LONP2 UCSF GRCh37 16 48385588 48385588 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 8 65 0 ENST00000285737.4:c.2434C>T p.Pro812Ser p.P812S ENST00000285737 NM_031490.2 812 Cca/Tca 0 +LOX UCSF GRCh37 5 121409721 121409721 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 13 158 0 ENST00000231004.4:c.1022C>T p.Thr341Ile p.T341I ENST00000231004 NM_002317.5 341 aCt/aTt 0 +LOXHD1 UCSF GRCh37 18 44057582 44057582 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 24 164 0 ENST00000300591.6:c.3307+35C>T *1103* ENST00000300591 NM_001145472.2 0 +LPAR4 UCSF GRCh37 X 78010399 78010399 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 25 103 0 ENST00000435339.3:c.33C>T p.Phe11= p.F11= ENST00000435339 NM_005296.2 11 ttC/ttT 0 +LPHN3 UCSF GRCh37 4 62679599 62679599 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 231 33 352 0 ENST00000514591.1:c.1268C>T p.Ser423Phe p.S423F ENST00000514591 423 tCt/tTt 0 +LPIN3 UCSF GRCh37 20 39980780 39980780 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 24 226 0 ENST00000373257.3:c.1283C>T p.Pro428Leu p.P428L ENST00000373257 NM_022896.1 428 cCt/cTt 0 +LPO UCSF GRCh37 17 56343536 56343536 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 28 158 0 ENST00000262290.4:c.1542G>A p.Arg514= p.R514= ENST00000262290 NM_006151.2 514 cgG/cgA 0 +LPP UCSF GRCh37 3 188426154 188426154 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 32 263 0 ENST00000312675.4:c.1213G>A p.Glu405Lys p.E405K ENST00000312675 NM_005578.3 405 Gaa/Aaa 0 +LPPR3 UCSF GRCh37 19 815058 815058 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 9 83 0 ENST00000520876.3:c.427G>A p.Ala143Thr p.A143T ENST00000520876 NM_001270366.1 143 Gcc/Acc 0 +LRBA UCSF GRCh37 4 151849989 151849989 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 19 265 0 ENST00000357115.3:c.445G>A p.Ala149Thr p.A149T ENST00000357115 NM_006726.4 149 Gca/Aca 0 +LRIG2 UCSF GRCh37 1 113616265 113616265 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 19 120 0 ENST00000361127.5:c.237C>T p.Ile79= p.I79= ENST00000361127 NM_014813.1 79 atC/atT 0 +LRP1 UCSF GRCh37 12 57594524 57594524 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 12 135 0 ENST00000243077.3:c.10151G>A p.Gly3384Asp p.G3384D ENST00000243077 NM_002332.2 3384 gGt/gAt 0 +LRP1 UCSF GRCh37 12 57539009 57539009 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 291 63 352 0 ENST00000243077.3:c.578-1G>A p.X193_splice ENST00000243077 NM_002332.2 0 +LRP10 UCSF GRCh37 14 23346348 23346348 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 25 182 0 ENST00000359591.4:c.1754C>T p.Ser585Phe p.S585F ENST00000359591 NM_014045.3 585 tCt/tTt 0 +LRP10 UCSF GRCh37 14 23345910 23345910 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 171 21 209 0 ENST00000359591.4:c.1437C>T p.Pro479= p.P479= ENST00000359591 NM_014045.3 479 ccC/ccT 0 +LRP10 UCSF GRCh37 14 23344297 23344297 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 473 284 799 0 ENST00000359591.4:c.249G>A p.Glu83= p.E83= ENST00000359591 NM_014045.3 83 gaG/gaA 0 +LRP12 UCSF GRCh37 8 105503379 105503379 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.0014 P24_Rec2 Untested WXS Illumina HiSeq 115 29 150 0 ENST00000276654.5:c.2102G>A p.Arg701Gln p.R701Q ENST00000276654 NM_013437.4 701 cGa/cAa 0 +LRP6 UCSF GRCh37 12 12419625 12419625 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 177 26 208 0 ENST00000261349.4:c.45G>A p.Val15= p.V15= ENST00000261349 NM_002336.2 15 gtG/gtA 0 +LRRC14B UCSF GRCh37 5 195220 195220 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 4 44 0 ENST00000328278.3:c.1297G>A p.Gly433Ser p.G433S ENST00000328278 NM_001080478.1 433 Ggt/Agt 0 +LRRC16B UCSF GRCh37 14 24531989 24531989 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 11 97 0 ENST00000342740.5:c.2640C>T p.Ser880= p.S880= ENST00000342740 NM_138360.3 880 tcC/tcT 0 +LRRC33 UCSF GRCh37 3 196387682 196387682 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 186 31 265 0 ENST00000328557.4:c.1168G>A p.Glu390Lys p.E390K ENST00000328557 NM_198565.1 390 Gag/Aag 0 +LRRC33 UCSF GRCh37 3 196386848 196386848 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 14 127 0 ENST00000328557.4:c.334C>T p.Leu112= p.L112= ENST00000328557 NM_198565.1 112 Ctg/Ttg 0 +LRRC43 UCSF GRCh37 12 122675926 122675926 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 8 66 0 ENST00000339777.4:c.902-1G>A p.X301_splice ENST00000339777 NM_152759.4 0 +LRRC4B UCSF GRCh37 19 51021391 51021391 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 29 197 0 ENST00000389201.3:c.1579C>T p.Pro527Ser p.P527S ENST00000389201 NM_001080457.1 527 Cct/Tct 0 +LRRC4C UCSF GRCh37 11 40137452 40137452 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 91 320 0 ENST00000278198.2:c.391C>T p.Leu131Phe p.L131F ENST00000278198 131 Ctc/Ttc 0 +LRRC61 UCSF GRCh37 7 150034302 150034302 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 40 253 0 ENST00000323078.7:c.352C>T p.Leu118= p.L118= ENST00000323078 NM_023942.2 118 Ctg/Ttg 0 +LRRC8A UCSF GRCh37 9 131669632 131669632 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 42 312 0 ENST00000259324.5:c.189C>T p.Asp63= p.D63= ENST00000259324 NM_001127244.1 63 gaC/gaT 0 +LRRC8B UCSF GRCh37 1 90049588 90049588 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 40 330 0 ENST00000330947.2:c.1379C>T p.Ser460Leu p.S460L ENST00000330947 NM_001134476.1 460 tCa/tTa 0 +LRRC8B UCSF GRCh37 1 90049725 90049725 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 23 169 0 ENST00000330947.2:c.1516G>A p.Val506Ile p.V506I ENST00000330947 NM_001134476.1 506 Gta/Ata 0 +LRRC8B UCSF GRCh37 1 90050269 90050269 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 64 526 0 ENST00000330947.2:c.2060G>A p.Ser687Asn p.S687N ENST00000330947 NM_001134476.1 687 aGc/aAc 0 +LRRC8E UCSF GRCh37 19 7963609 7963609 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 272 32 261 0 ENST00000306708.6:c.202C>T p.Pro68Ser p.P68S ENST00000306708 NM_025061.4 68 Ccg/Tcg 0 +LRRFIP1 UCSF GRCh37 2 238683017 238683017 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 9 49 0 ENST00000308482.9:c.1724G>A p.Ser575Asn p.S575N ENST00000308482 NM_001137550.1 575 aGt/aAt 0 +LRRN4 UCSF GRCh37 20 6031501 6031501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 7 103 0 ENST00000378858.4:c.784G>A p.Asp262Asn p.D262N ENST00000378858 NM_152611.4 262 Gac/Aac 0 +LRWD1 UCSF GRCh37 7 102110255 102110255 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 261 46 313 0 ENST00000292616.5:c.1368C>T p.Asp456= p.D456= ENST00000292616 NM_152892.1 456 gaC/gaT 0 +LTA UCSF GRCh37 6 31541433 31541433 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 38 278 0 ENST00000454783.1:c.581G>A p.Ser194Asn p.S194N ENST00000454783 NM_001159740.2 194 aGc/aAc 0 +LTBP1 UCSF GRCh37 2 33590523 33590523 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 32 0 ENST00000404816.2:c.4664G>A p.Gly1555Glu p.G1555E ENST00000404816 1555 gGa/gAa 0 +LTBP4 UCSF GRCh37 19 41128865 41128865 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 70 191 0 ENST00000308370.7:c.3693G>A p.Gln1231= p.Q1231= ENST00000308370 NM_001042544.1 1231 caG/caA 0 +LUZP1 UCSF GRCh37 1 23418977 23418977 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 305 48 390 0 ENST00000302291.4:c.1778G>A p.Ser593Asn p.S593N ENST00000302291 593 aGt/aAt 0 +LY6G6F UCSF GRCh37 6 31675669 31675669 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 19 143 0 ENST00000375832.4:c.404C>T p.Ala135Val p.A135V ENST00000375832 NM_001003693.1 135 gCt/gTt 0 +LYG2 UCSF GRCh37 2 99860569 99860569 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 15 130 0 ENST00000333017.2:c.413C>T p.Ala138Val p.A138V ENST00000333017 NM_175735.3 138 gCc/gTc 0 +LYL1 UCSF GRCh37 19 13211472 13211472 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 737 87 717 0 ENST00000264824.4:c.426G>A p.Glu142= p.E142= ENST00000264824 NM_005583.4 142 gaG/gaA 0 +MAB21L2 UCSF GRCh37 4 151504418 151504418 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 20 186 0 ENST00000317605.4:c.237C>T p.Tyr79= p.Y79= ENST00000317605 NM_006439.4 79 taC/taT 0 +MACF1 UCSF GRCh37 1 39846008 39846008 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 8 87 0 ENST00000372915.3:c.13626G>A p.Gln4542= p.Q4542= ENST00000372915 4542 caG/caA 0 +MAEL UCSF GRCh37 1 166973532 166973532 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 11 101 0 ENST00000367872.4:c.639C>T p.Ile213= p.I213= ENST00000367872 NM_032858.1 213 atC/atT 0 +MAGED1 UCSF GRCh37 X 51640158 51640158 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 11 144 0 ENST00000326587.7:c.1407C>T p.Ala469= p.A469= ENST00000326587 NM_006986.3 469 gcC/gcT 0 +MAGEF1 UCSF GRCh37 3 184429328 184429328 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 584 91 780 0 ENST00000317897.3:c.282G>A p.Lys94= p.K94= ENST00000317897 NM_022149.4 94 aaG/aaA 0 +MAGEL2 UCSF GRCh37 15 23889682 23889682 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 203 27 277 0 ENST00000532292.1:c.1399G>A p.Glu467Lys p.E467K ENST00000532292 NM_019066.4 467 Gag/Aag 0 +MAGEL2 UCSF GRCh37 15 23890315 23890315 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 33 215 0 ENST00000532292.1:c.766G>A p.Ala256Thr p.A256T ENST00000532292 NM_019066.4 256 Gca/Aca 0 +MAK16 UCSF GRCh37 8 33354807 33354807 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 13 89 0 ENST00000360128.6:c.697G>A p.Asp233Asn p.D233N ENST00000360128 NM_032509.3 233 Gat/Aat 0 +MAOB UCSF GRCh37 X 43655077 43655077 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 27 165 0 ENST00000378069.4:c.677G>A p.Gly226Glu p.G226E ENST00000378069 NM_000898.4 226 gGa/gAa 0 +MAP1A UCSF GRCh37 15 43818123 43818123 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 12 120 0 ENST00000300231.5:c.4452C>T p.Val1484= p.V1484= ENST00000300231 1484 gtC/gtT 0 +MAP2 UCSF GRCh37 2 210560342 210560342 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 82 238 0 ENST00000360351.4:c.3448G>A p.Gly1150Ser p.G1150S ENST00000360351 NM_002374.3 1150 Ggc/Agc 0 +MAP2K1 UCSF GRCh37 15 66727510 66727510 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 12 90 0 ENST00000307102.5:c.226G>A p.Ala76Thr p.A76T ENST00000307102 NM_002755.3 76 Gct/Act 0 +MAP2K1 UCSF GRCh37 15 66782084 66782084 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 273 58 396 0 ENST00000307102.5:c.1051G>A p.Asp351Asn p.D351N ENST00000307102 NM_002755.3 351 Gat/Aat 0 +MAP3K5 UCSF GRCh37 6 136926391 136926391 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 19 45 0 ENST00000359015.4:c.2635C>T p.Pro879Ser p.P879S ENST00000359015 NM_005923.3 879 Ccc/Tcc 0 +MAP3K6 UCSF GRCh37 1 27684060 27684060 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 21 196 0 ENST00000357582.2:c.3089G>A p.Arg1030His p.R1030H ENST00000357582 1030 cGt/cAt 0 +MAP3K6 UCSF GRCh37 1 27685280 27685280 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 24 124 0 ENST00000357582.2:c.2503C>T p.Leu835= p.L835= ENST00000357582 835 Ctg/Ttg 0 +MAP3K7 UCSF GRCh37 6 91226378 91226378 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 14 117 0 ENST00000369329.3:c.1663G>A p.Asp555Asn p.D555N ENST00000369329 NM_145331.2 555 Gac/Aac 0 +MAP4K3 UCSF GRCh37 2 39487780 39487780 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 18 180 0 ENST00000263881.3:c.2275C>T p.Pro759Ser p.P759S ENST00000263881 NM_003618.3 759 Cca/Tca 0 +MAP7D1 UCSF GRCh37 1 36643628 36643628 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 22 142 0 ENST00000373151.2:c.1534G>A p.Glu512Lys p.E512K ENST00000373151 NM_018067.3 512 Gag/Aag 0 +MAPK11 UCSF GRCh37 22 50705860 50705860 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 3 53 0 ENST00000330651.6:c.357C>T p.Cys119= p.C119= ENST00000330651 NM_002751.5 119 tgC/tgT 0 +MAPK8IP3 UCSF GRCh37 16 1816017 1816017 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 13 137 0 ENST00000250894.4:c.2500C>T p.Pro834Ser p.P834S ENST00000250894 NM_015133.3 834 Cca/Tca 0 +MAPKAP1 UCSF GRCh37 9 128434850 128434850 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 12 83 0 ENST00000265960.3:c.4G>A p.Ala2Thr p.A2T ENST00000265960 NM_001006617.1 2 Gcc/Acc 0 +MARK4 UCSF GRCh37 19 45769492 45769492 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 46 207 0 ENST00000262891.4:c.502G>T p.Ala168Ser p.A168S ENST00000262891 NM_001199867.1 168 Gct/Tct 0 +MARS UCSF GRCh37 12 57882776 57882802 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TAACCCATTTTCCATTCTTGCATCAGA TAACCCATTTTCCATTCTTGCATCAGA AACCCATTTTCCCTTCTTGCCTCAGT NOVEL P24_Rec2 Untested WXS Illumina HiSeq 7 0 ENST00000262027.5:c.110-26_110delinsAACCCATTTTCCCTTCTTGCCTCAGT p.X37_splice ENST00000262027 NM_004990.3 0 +MARS UCSF GRCh37 12 57908940 57908940 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 797 102 262 1 ENST00000262027.5:c.2212G>A p.Ala738Thr p.A738T ENST00000262027 NM_004990.3 738 Gca/Aca 0 +MATN2 UCSF GRCh37 8 98943633 98943633 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 18 148 0 ENST00000254898.5:c.595G>A p.Val199Ile p.V199I ENST00000254898 NM_002380.3 199 Gta/Ata 0 +MATN2 UCSF GRCh37 8 98973655 98973655 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 19 195 0 ENST00000254898.5:c.855G>A p.Met285Ile p.M285I ENST00000254898 NM_002380.3 285 atG/atA 0 +MAVS UCSF GRCh37 20 3843000 3843000 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 8 84 0 ENST00000428216.2:c.565C>T p.Pro189Ser p.P189S ENST00000428216 NM_020746.4 189 Cct/Tct 0 +MBOAT7 UCSF GRCh37 19 54684759 54684759 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 63 0 ENST00000245615.1:c.585C>T p.Ala195= p.A195= ENST00000245615 NM_024298.3 195 gcC/gcT 0 +MBP UCSF GRCh37 18 74700469 74700469 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 8 81 0 ENST00000355994.2:c.732C>T p.Ser244= p.S244= ENST00000355994 NM_001025101.1 244 tcC/tcT 0 +MCF2L UCSF GRCh37 13 113718681 113718681 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 12 135 0 ENST00000375608.3:c.643G>A p.Asp215Asn p.D215N ENST00000375608 215 Gac/Aac 0 +MCM3AP UCSF GRCh37 21 47655304 47655304 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 34 245 0 ENST00000291688.1:c.5821G>A p.Ala1941Thr p.A1941T ENST00000291688 NM_003906.3 1941 Gcg/Acg 0 +MCM3AP UCSF GRCh37 21 47664949 47664949 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 20 193 1 ENST00000291688.1:c.4810G>A p.Glu1604Lys p.E1604K ENST00000291688 NM_003906.3 1604 Gag/Aag 0 +MCM5 UCSF GRCh37 22 35799454 35799454 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 26 174 0 ENST00000216122.4:c.342G>A p.Arg114= p.R114= ENST00000216122 NM_006739.3 114 cgG/cgA 0 +MCM5 UCSF GRCh37 22 35812631 35812631 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 26 191 0 ENST00000216122.4:c.1414G>A p.Ala472Thr p.A472T ENST00000216122 NM_006739.3 472 Gct/Act 0 +MCM9 UCSF GRCh37 6 119147334 119147334 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 225 39 322 0 ENST00000316316.6:c.1937G>A p.Ser646Asn p.S646N ENST00000316316 NM_017696.2 646 aGt/aAt 0 +MCOLN1 UCSF GRCh37 19 7591692 7591692 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 35 107 0 ENST00000264079.6:c.451C>T p.Arg151Cys p.R151C ENST00000264079 NM_020533.2 151 Cgt/Tgt 0 +MCTP2 UCSF GRCh37 15 94841544 94841544 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 14 117 0 ENST00000357742.4:c.50G>A p.Arg17Lys p.R17K ENST00000357742 NM_018349.3 17 aGg/aAg 0 +MDGA1 UCSF GRCh37 6 37617999 37617999 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 17 85 0 ENST00000434837.3:c.1495C>T p.Leu499= p.L499= ENST00000434837 NM_153487.3 499 Ctg/Ttg 0 +ME3 UCSF GRCh37 11 86158185 86158185 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 18 155 0 ENST00000393324.3:c.1302G>A p.Glu434= p.E434= ENST00000393324 NM_001014811.1 434 gaG/gaA 0 +MECP2 UCSF GRCh37 X 153297923 153297923 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 9 78 0 ENST00000303391.6:c.112G>A p.Glu38Lys p.E38K ENST00000303391 NM_004992.3 38 Gag/Aag 0 +MECR UCSF GRCh37 1 29542612 29542612 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 5 39 0 ENST00000263702.6:c.311G>A p.Gly104Glu p.G104E ENST00000263702 104 gGa/gAa 0 +MED1 UCSF GRCh37 17 37564974 37564974 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 48 363 0 ENST00000300651.6:c.3500C>T p.Ser1167Phe p.S1167F ENST00000300651 NM_004774.3 1167 tCt/tTt 0 +MED13L UCSF GRCh37 12 116450687 116450687 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 18 174 0 ENST00000281928.3:c.1195C>T p.Pro399Ser p.P399S ENST00000281928 NM_015335.4 399 Cca/Tca 0 +MED26 UCSF GRCh37 19 16687952 16687952 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 41 255 0 ENST00000263390.3:c.689C>T p.Thr230Ile p.T230I ENST00000263390 NM_004831.3 230 aCc/aTc 0 +MED27 UCSF GRCh37 9 134738489 134738489 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 10 80 0 ENST00000292035.5:c.762G>A p.Gln254= p.Q254= ENST00000292035 NM_004269.3 254 caG/caA 0 +MEF2B UCSF GRCh37 19 19257685 19257685 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 12 97 0 ENST00000162023.5:c.542-1G>A p.X181_splice ENST00000162023 0 +MEGF8 UCSF GRCh37 19 42858034 42858034 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 25 243 0 ENST00000251268.6:c.3869G>A p.Gly1290Asp p.G1290D ENST00000251268 1290 gGc/gAc 0 +MEGF8 UCSF GRCh37 19 42863080 42863080 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 6 19 0 ENST00000251268.6:c.5317G>A p.Glu1773Lys p.E1773K ENST00000251268 1773 Gag/Aag 0 +MEGF8 UCSF GRCh37 19 42848871 42848871 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 22 184 0 ENST00000251268.6:c.1983G>A p.Trp661Ter p.W661* ENST00000251268 661 tgG/tgA 0 +MEI1 UCSF GRCh37 22 42144223 42144223 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 8 74 0 ENST00000401548.3:c.1792+1G>A p.X598_splice ENST00000401548 NM_152513.3 0 +MEIS3 UCSF GRCh37 19 47920520 47920520 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 5 21 0 ENST00000558555.1:c.100C>T p.Pro34Ser p.P34S ENST00000558555 34 Ccc/Tcc 0 +MEOX1 UCSF GRCh37 17 41720962 41720962 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 15 85 0 ENST00000318579.4:c.536C>T p.Thr179Ile p.T179I ENST00000318579 NM_001040002.1 179 aCc/aTc 0 +MET UCSF GRCh37 7 116339509 116339509 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 319 108 417 0 ENST00000397752.3:c.371C>T p.Thr124Ile p.T124I ENST00000397752 NM_000245.2 124 aCc/aTc 0 +METRN UCSF GRCh37 16 765688 765688 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 8 22 0 ENST00000568223.2:c.209G>A p.Gly70Asp p.G70D ENST00000568223 NM_024042.2 70 gGc/gAc 0 +MFSD10 UCSF GRCh37 4 2934423 2934423 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 17 109 0 ENST00000329687.4:c.435C>T p.Ala145= p.A145= ENST00000329687 NM_001120.4 145 gcC/gcT 0 +MFSD11 UCSF GRCh37 17 74735066 74735066 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 42 282 0 ENST00000336509.4:c.143G>A p.Gly48Glu p.G48E ENST00000336509 NM_001242533.1 48 gGa/gAa 0 +MGA UCSF GRCh37 15 42054537 42054537 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 18 131 0 ENST00000219905.7:c.7721C>T p.Ser2574Phe p.S2574F ENST00000219905 NM_001164273.1 2574 tCc/tTc 0 +MGAM UCSF GRCh37 7 141724908 141724908 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 19 188 0 ENST00000549489.2:c.941G>A p.Gly314Glu p.G314E ENST00000549489 NM_004668.2 314 gGa/gAa 0 +MIB1 UCSF GRCh37 18 19395702 19395702 + synonymous_variant Silent SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 59 221 0 ENST00000261537.6:c.1605T>C p.His535= p.H535= ENST00000261537 NM_020774.3 535 caT/caC 0 +MICAL2 UCSF GRCh37 11 12183794 12183794 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 37 283 0 ENST00000256194.4:c.92C>T p.Ala31Val p.A31V ENST00000256194 NM_014632.2 31 gCc/gTc 0 +MICAL3 UCSF GRCh37 22 18301123 18301123 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 6 29 0 ENST00000441493.2:c.4304C>T p.Ser1435Phe p.S1435F ENST00000441493 NM_015241.2 1435 tCc/tTc 0 +MICALCL UCSF GRCh37 11 12315524 12315524 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 16 168 0 ENST00000256186.2:c.546C>T p.Val182= p.V182= ENST00000256186 NM_032867.2 182 gtC/gtT 0 +MICB UCSF GRCh37 6 31466001 31466001 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 10 110 0 ENST00000252229.6:c.31G>A p.Ala11Thr p.A11T ENST00000252229 NM_005931.3 11 Gcc/Acc 0 +MLL3 UCSF GRCh37 7 151880171 151880171 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 25 183 0 ENST00000262189.6:c.5153G>A p.Arg1718Lys p.R1718K ENST00000262189 NM_170606.2 1718 aGg/aAg 0 +MLL3 UCSF GRCh37 7 152012300 152012300 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 16 153 0 ENST00000262189.6:c.513G>A p.Lys171= p.K171= ENST00000262189 NM_170606.2 171 aaG/aaA 0 +MLL4 UCSF GRCh37 19 36221339 36221339 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 231 676 1 ENST00000420124.1:c.5173C>T p.Pro1725Ser p.P1725S ENST00000420124 1725 Ccc/Tcc 0 +MLL4 UCSF GRCh37 19 36223240 36223240 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 56 433 0 ENST00000420124.1:c.5790C>T p.Ser1930= p.S1930= ENST00000420124 1930 tcC/tcT 0 +MLL5 UCSF GRCh37 7 104745961 104745961 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 330 66 456 0 ENST00000257745.4:c.2272C>T p.Leu758= p.L758= ENST00000257745 NM_018682.3 758 Cta/Tta 0 +MMEL1 UCSF GRCh37 1 2540829 2540829 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 56 0 ENST00000378412.3:c.484C>T p.Arg162Trp p.R162W ENST00000378412 162 Cgg/Tgg 0 +MMP1 UCSF GRCh37 11 102666337 102666337 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 8 56 0 ENST00000315274.6:c.627G>A p.Glu209= p.E209= ENST00000315274 NM_002421.3 209 gaG/gaA 0 +MMP13 UCSF GRCh37 11 102819875 102819875 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 14 136 0 ENST00000260302.3:c.930C>T p.Arg310= p.R310= ENST00000260302 NM_002427.3 310 cgC/cgT 0 +MMP15 UCSF GRCh37 16 58075765 58075765 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 7 90 0 ENST00000219271.3:c.1155C>T p.Phe385= p.F385= ENST00000219271 NM_002428.2 385 ttC/ttT 0 +MMP3 UCSF GRCh37 11 102712885 102712885 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 9 66 0 ENST00000299855.5:c.625G>A p.Gly209Arg p.G209R ENST00000299855 NM_002422.3 209 Ggg/Agg 0 +MN1 UCSF GRCh37 22 28193613 28193613 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 16 113 0 ENST00000302326.4:c.2919G>A p.Gly973= p.G973= ENST00000302326 NM_002430.2 973 ggG/ggA 0 +MOB3B UCSF GRCh37 9 27359113 27359113 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 25 255 0 ENST00000262244.5:c.540C>T p.Ala180= p.A180= ENST00000262244 NM_024761.4 180 gcC/gcT 0 +MORC1 UCSF GRCh37 3 108829620 108829620 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 5 20 0 ENST00000232603.5:c.130G>A p.Ala44Thr p.A44T ENST00000232603 NM_014429.3 44 Gct/Act 0 +MPHOSPH9 UCSF GRCh37 12 123651312 123651312 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 17 102 0 ENST00000606320.1:c.2481C>T p.Ser827= p.S827= ENST00000606320 NM_022782.3 827 agC/agT 0 +MPL UCSF GRCh37 1 43817944 43817944 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 18 159 0 ENST00000372470.3:c.1623G>A p.Gln541= p.Q541= ENST00000372470 NM_005373.2 541 caG/caA 0 +MPO UCSF GRCh37 17 56357791 56357791 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 6 63 0 ENST00000225275.3:c.184G>A p.Val62Met p.V62M ENST00000225275 NM_000250.1 62 Gtg/Atg 0 +MPZL3 UCSF GRCh37 11 118104212 118104212 + missense_variant Missense_Mutation SNP C C T snp132_rs116163888 P24_Rec2 Untested WXS Illumina HiSeq 175 30 237 0 ENST00000278949.4:c.644G>A p.Cys215Tyr p.C215Y ENST00000278949 215 tGt/tAt 0 +MRGPRF UCSF GRCh37 11 68773465 68773465 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 14 146 0 ENST00000309099.6:c.313G>A p.Gly105Arg p.G105R ENST00000309099 NM_145015.4 105 Ggg/Agg 0 +MRPL2 UCSF GRCh37 6 43024112 43024112 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 28 224 0 ENST00000388752.3:c.337C>T p.Arg113Trp p.R113W ENST00000388752 NM_015950.3 113 Cgg/Tgg 0 +MRPS18B UCSF GRCh37 6 30587281 30587281 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 31 317 0 ENST00000259873.4:c.90G>A p.Gln30= p.Q30= ENST00000259873 NM_014046.3 30 caG/caA 0 +MRPS35 UCSF GRCh37 12 27863847 27863847 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 21 198 0 ENST00000081029.3:c.71C>T p.Thr24Ile p.T24I ENST00000081029 NM_021821.3 24 aCt/aTt 0 +MRPS5 UCSF GRCh37 2 95770404 95770404 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 228 33 340 0 ENST00000272418.2:c.744G>A p.Gly248= p.G248= ENST00000272418 NM_031902.3 248 ggG/ggA 0 +MS4A15 UCSF GRCh37 11 60531267 60531267 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 231 157 483 0 ENST00000405633.3:c.61G>A p.Gly21Ser p.G21S ENST00000405633 NM_001098835.1 21 Ggc/Agc 0 +MS4A6E UCSF GRCh37 11 60105330 60105330 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0042 P24_Rec2 Untested WXS Illumina HiSeq 85 42 193 0 ENST00000300182.4:c.264C>T p.Asp88= p.D88= ENST00000300182 NM_139249.2 88 gaC/gaT 0 +MSH4 UCSF GRCh37 1 76269570 76269570 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 21 218 0 ENST00000263187.3:c.399G>A p.Lys133= p.K133= ENST00000263187 NM_002440.3 133 aaG/aaA 0 +MSH5 UCSF GRCh37 6 31710893 31710893 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 3 23 0 ENST00000375750.3:c.361G>A p.Glu121Lys p.E121K ENST00000375750 NM_172165.3 121 Gag/Aag 0 +MSH6 UCSF GRCh37 2 48026834 48026834 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 154 95 325 0 ENST00000234420.5:c.1712G>A p.Gly571Asp p.G571D ENST00000234420 NM_000179.2 571 gGt/gAt 0 +MSH6 UCSF GRCh37 2 48032083 48032083 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 103 61 192 0 ENST00000234420.5:c.3473G>A p.Cys1158Tyr p.C1158Y ENST00000234420 NM_000179.2 1158 tGt/tAt 0 +MSLN UCSF GRCh37 16 817429 817429 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 35 0 ENST00000382862.3:c.1579G>A p.Asp527Asn p.D527N ENST00000382862 NM_013404.4 527 Gac/Aac 0 +MSLN UCSF GRCh37 16 812704 812704 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 29 217 0 ENST00000382862.3:c.24C>T p.Pro8= p.P8= ENST00000382862 NM_013404.4 8 ccC/ccT 0 +MTERFD3 UCSF GRCh37 12 107372461 107372461 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 123 16 169 0 ENST00000240050.4:c.32C>T p.Ser11Phe p.S11F ENST00000240050 NM_001033050.2 11 tCc/tTc 0 +MTFMT UCSF GRCh37 15 65298465 65298465 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 22 238 0 ENST00000220058.4:c.878G>A p.Ser293Asn p.S293N ENST00000220058 NM_139242.3 293 aGt/aAt 0 +MTHFD2 UCSF GRCh37 2 74438910 74438910 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 8 46 0 ENST00000394053.2:c.806C>T p.Ala269Val p.A269V ENST00000394053 NM_006636.3 269 gCa/gTa 0 +MTMR3 UCSF GRCh37 22 30403157 30403157 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 8 31 0 ENST00000401950.2:c.726G>A p.Trp242Ter p.W242* ENST00000401950 NM_021090.3 242 tgG/tgA 0 +MTNR1B UCSF GRCh37 11 92714758 92714758 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 49 306 1 ENST00000257068.2:c.369C>T p.Ser123= p.S123= ENST00000257068 NM_005959.3 123 agC/agT 0 +MTUS1 UCSF GRCh37 8 17504501 17504501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 139 269 0 ENST00000262102.6:c.3589G>A p.Ala1197Thr p.A1197T ENST00000262102 NM_001001924.2 1197 Gca/Aca 0 +MUC1 UCSF GRCh37 1 155161911 155161911 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 14 130 0 ENST00000368395.1:c.222G>A p.Gln74= p.Q74= ENST00000368395 NM_001204285.1 74 caG/caA 0 +MUC16 UCSF GRCh37 19 9073741 9073741 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 20 166 0 ENST00000397910.4:c.13705G>A p.Val4569Ile p.V4569I ENST00000397910 NM_024690.2 4569 Gtt/Att 0 +MUC16 UCSF GRCh37 19 9060954 9060954 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 247 29 276 0 ENST00000397910.4:c.26492C>T p.Pro8831Leu p.P8831L ENST00000397910 NM_024690.2 8831 cCt/cTt 0 +MUC2 UCSF GRCh37 11 1090790 1090790 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 11 126 0 ENST00000441003.2:c.3685C>T p.Leu1229Phe p.L1229F ENST00000441003 NM_002457.2 1229 Ctt/Ttt 0 +MUC2 UCSF GRCh37 11 1096427 1096427 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 24 183 0 ENST00000441003.2:c.6452C>T p.Pro2151Leu p.P2151L ENST00000441003 NM_002457.2 2151 cCc/cTc 0 +MUC5B UCSF GRCh37 11 1250966 1250966 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 30 285 0 ENST00000529681.1:c.1149G>A p.Gly383= p.G383= ENST00000529681 NM_002458.2 383 ggG/ggA 0 +MUC6 UCSF GRCh37 11 1030681 1030681 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 12 103 0 ENST00000421673.2:c.784C>T p.Pro262Ser p.P262S ENST00000421673 NM_005961.2 262 Ccc/Tcc 0 +MUM1 UCSF GRCh37 19 1371047 1371047 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 253 32 227 0 ENST00000344663.3:c.1959C>T p.Ile653= p.I653= ENST00000344663 653 atC/atT 0 +MVP UCSF GRCh37 16 29855860 29855860 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 24 196 0 ENST00000357402.5:c.1681C>T p.Leu561Phe p.L561F ENST00000357402 NM_017458.3 561 Ctc/Ttc 0 +MXRA8 UCSF GRCh37 1 1290246 1290246 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 16 142 0 ENST00000309212.6:c.765C>T p.Phe255= p.F255= ENST00000309212 NM_032348.2 255 ttC/ttT 0 +MYADM UCSF GRCh37 19 54377419 54377419 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 171 31 267 0 ENST00000336967.3:c.636C>T p.Ile212= p.I212= ENST00000336967 NM_001020820.1 212 atC/atT 0 +MYCL1 UCSF GRCh37 1 40363471 40363471 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 28 214 0 ENST00000372816.2:c.668G>A p.Cys223Tyr p.C223Y ENST00000372816 223 tGc/tAc 0 +MYH1 UCSF GRCh37 17 10411982 10411982 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 10 5 24 0 ENST00000226207.5:c.1595G>A p.Gly532Asp p.G532D ENST00000226207 NM_005963.3 532 gGc/gAc 0 +MYH1 UCSF GRCh37 17 10415188 10415188 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 11 26 0 ENST00000226207.5:c.1384G>A p.Val462Ile p.V462I ENST00000226207 NM_005963.3 462 Gtc/Atc 0 +MYH10 UCSF GRCh37 17 8473102 8473102 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 10 114 0 ENST00000269243.4:c.662C>T p.Ala221Val p.A221V ENST00000269243 NM_005964.3 221 gCa/gTa 0 +MYH11 UCSF GRCh37 16 15818827 15818827 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 18 170 0 ENST00000300036.5:c.3881G>A p.Gly1294Glu p.G1294E ENST00000300036 NM_002474.2 1294 gGg/gAg 0 +MYH2 UCSF GRCh37 17 10440993 10440993 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 49 0 ENST00000245503.5:c.1576C>T p.Leu526Phe p.L526F ENST00000245503 NM_017534.5 526 Ctc/Ttc 0 +MYH9 UCSF GRCh37 22 36702043 36702043 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 13 116 0 ENST00000216181.5:c.2092C>A p.Leu698Ile p.L698I ENST00000216181 NM_002473.4 698 Ctc/Atc 0 +MYLK UCSF GRCh37 3 123452730 123452730 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 175 24 208 0 ENST00000360304.3:c.1113G>A p.Arg371= p.R371= ENST00000360304 NM_053025.3 371 agG/agA 0 +MYO15A UCSF GRCh37 17 18055258 18055258 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 76 213 1 ENST00000205890.5:c.7886G>A p.Gly2629Asp p.G2629D ENST00000205890 NM_016239.3 2629 gGc/gAc 0 +MYO18A UCSF GRCh37 17 27424829 27424829 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 41 300 1 ENST00000527372.1:c.4079G>A p.Gly1360Glu p.G1360E ENST00000527372 NM_078471.3 1360 gGg/gAg 0 +MYO18A UCSF GRCh37 17 27448665 27448665 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 10 49 0 ENST00000527372.1:c.1271C>T p.Thr424Ile p.T424I ENST00000527372 NM_078471.3 424 aCc/aTc 0 +MYO5A UCSF GRCh37 15 52708393 52708393 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 11 94 0 ENST00000399231.3:c.561C>T p.Ala187= p.A187= ENST00000399231 NM_000259.3 187 gcC/gcT 0 +MYO5B UCSF GRCh37 18 47431193 47431193 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 12 120 0 ENST00000285039.7:c.2420C>T p.Ala807Val p.A807V ENST00000285039 NM_001080467.2 807 gCt/gTt 0 +MYO7A UCSF GRCh37 11 76895733 76895733 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 19 142 0 ENST00000409709.3:c.3476G>A p.Gly1159Asp p.G1159D ENST00000409709 NM_000260.3 1159 gGc/gAc 0 +MYO7B UCSF GRCh37 2 128383042 128383042 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 18 190 0 ENST00000409816.2:c.4069C>T p.Pro1357Ser p.P1357S ENST00000409816 1357 Ccc/Tcc 0 +MYO7B UCSF GRCh37 2 128387376 128387376 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 10 59 0 ENST00000409816.2:c.4703T>C p.Val1568Ala p.V1568A ENST00000409816 1568 gTc/gCc 0 +MYO7B UCSF GRCh37 2 128339968 128339968 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 13 122 0 ENST00000409816.2:c.1290G>A p.Arg430= p.R430= ENST00000409816 430 cgG/cgA 0 +MYO9A UCSF GRCh37 15 72190181 72190181 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 198 35 287 0 ENST00000356056.5:c.4663G>A p.Glu1555Lys p.E1555K ENST00000356056 NM_006901.3 1555 Gag/Aag 0 +MYO9A UCSF GRCh37 15 72196314 72196314 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 9 132 0 ENST00000356056.5:c.2833G>A p.Val945Ile p.V945I ENST00000356056 NM_006901.3 945 Gtt/Att 0 +MYOM1 UCSF GRCh37 18 3215166 3215166 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 14 84 0 ENST00000356443.4:c.56A>G p.Asn19Ser p.N19S ENST00000356443 NM_019856.1 19 aAc/aGc 0 +MYOT UCSF GRCh37 5 137206617 137206617 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 378 59 588 0 ENST00000239926.4:c.277C>T p.Pro93Ser p.P93S ENST00000239926 NM_006790.2 93 Cca/Tca 0 +MYOZ2 UCSF GRCh37 4 120072107 120072107 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 17 198 0 ENST00000307128.5:c.157C>T p.Arg53Cys p.R53C ENST00000307128 NM_016599.4 53 Cgt/Tgt 0 +NAB1 UCSF GRCh37 2 191551996 191551996 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 53 340 0 ENST00000337386.5:c.1328G>A p.Gly443Glu p.G443E ENST00000337386 NM_005966.3 443 gGg/gAg 0 +NACAD UCSF GRCh37 7 45124928 45124928 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 12 55 0 ENST00000490531.2:c.851G>A p.Ser284Asn p.S284N ENST00000490531 NM_001146334.1 284 aGc/aAc 0 +NAGPA UCSF GRCh37 16 5081863 5081863 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 27 183 0 ENST00000312251.3:c.565C>T p.Leu189= p.L189= ENST00000312251 NM_016256.3 189 Ctg/Ttg 0 +NALCN UCSF GRCh37 13 101753175 101753175 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 10 67 0 ENST00000251127.6:c.3122G>A p.Gly1041Glu p.G1041E ENST00000251127 NM_052867.2 1041 gGa/gAa 0 +NASP UCSF GRCh37 1 46073227 46073227 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 4 25 0 ENST00000350030.3:c.644G>A p.Gly215Glu p.G215E ENST00000350030 NM_002482.3 215 gGa/gAa 0 +NAT10 UCSF GRCh37 11 34129869 34129869 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 31 136 0 ENST00000257829.3:c.97G>A p.Gly33Arg p.G33R ENST00000257829 NM_024662.2 33 Gga/Aga 0 +NAV1 UCSF GRCh37 1 201750262 201750262 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 13 151 0 ENST00000367296.4:c.1488G>A p.Gly496= p.G496= ENST00000367296 NM_020443.4 496 ggG/ggA 0 +NAV2 UCSF GRCh37 11 20044667 20044667 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 6 35 0 ENST00000396087.3:c.2838-12838G>A *946* ENST00000396087 NM_001244963.1 0 +NAV3 UCSF GRCh37 12 78400710 78400710 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 10 137 0 ENST00000397909.2:c.1392G>A p.Gln464= p.Q464= ENST00000397909 NM_001024383.1 464 caG/caA 0 +NBEA UCSF GRCh37 13 35751142 35751142 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 17 209 0 ENST00000400445.3:c.4564G>A p.Glu1522Lys p.E1522K ENST00000400445 NM_015678.4 1522 Gaa/Aaa 0 +NCAPG2 UCSF GRCh37 7 158454921 158454921 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0014,snp132_rs61746693 P24_Rec2 Untested WXS Illumina HiSeq 145 17 151 0 ENST00000356309.3:c.1954G>A p.Ala652Thr p.A652T ENST00000356309 NM_017760.5 652 Gcc/Acc 0 +NCKAP1L UCSF GRCh37 12 54920453 54920453 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 58 184 0 ENST00000293373.6:c.2298C>T p.Ile766= p.I766= ENST00000293373 NM_005337.4 766 atC/atT 0 +NCKAP5 UCSF GRCh37 2 133542583 133542583 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 427 66 634 0 ENST00000409261.1:c.1801C>T p.Pro601Ser p.P601S ENST00000409261 NM_207363.2 601 Cct/Tct 0 +NCL UCSF GRCh37 2 232326445 232326445 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 370 51 544 0 ENST00000322723.4:c.419C>T p.Ala140Val p.A140V ENST00000322723 NM_005381.2 140 gCc/gTc 0 +NCL UCSF GRCh37 2 232319968 232319968 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 384 64 581 1 ENST00000322723.4:c.2067C>T p.Gly689= p.G689= ENST00000322723 NM_005381.2 689 ggC/ggT 0 +NCOA6 UCSF GRCh37 20 33328235 33328235 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 20 154 0 ENST00000359003.2:c.5825C>T p.Ser1942Phe p.S1942F ENST00000359003 NM_014071.3 1942 tCt/tTt 0 +NCOR2 UCSF GRCh37 12 124821445 124821445 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 10 64 0 ENST00000405201.1:c.5969C>T p.Thr1990Ile p.T1990I ENST00000405201 1990 aCc/aTc 0 +NDUFA7 UCSF GRCh37 19 8386193 8386193 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 8 41 0 ENST00000301457.2:c.50G>A p.Gly17Glu p.G17E ENST00000301457 NM_005001.3 17 gGg/gAg 0 +NEDD4L UCSF GRCh37 18 56033398 56033398 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 136 19 177 0 ENST00000400345.3:c.2001G>A p.Trp667Ter p.W667* ENST00000400345 NM_001144967.2 667 tgG/tgA 0 +NEDD9 UCSF GRCh37 6 11213641 11213641 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 32 212 0 ENST00000379446.5:c.332C>T p.Ser111Phe p.S111F ENST00000379446 NM_001271033.1 111 tCc/tTc 0 +NEK5 UCSF GRCh37 13 52701586 52701586 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 28 306 0 ENST00000355568.4:c.33G>A p.Gly11= p.G11= ENST00000355568 NM_199289.1 11 ggG/ggA 0 +NELF UCSF GRCh37 9 140347022 140347022 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 12 115 0 ENST00000371475.3:c.1148C>T p.Thr383Ile p.T383I ENST00000371475 NM_001130969.1 383 aCc/aTc 0 +NES UCSF GRCh37 1 156639827 156639827 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 322 174 541 1 ENST00000368223.3:c.4153G>A p.Glu1385Lys p.E1385K ENST00000368223 NM_006617.1 1385 Gag/Aag 0 +NES UCSF GRCh37 1 156646436 156646436 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 15 114 0 ENST00000368223.3:c.621C>T p.Ala207= p.A207= ENST00000368223 NM_006617.1 207 gcC/gcT 0 +NEURL4 UCSF GRCh37 17 7229659 7229659 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 19 141 0 ENST00000399464.2:c.1208C>T p.Thr403Ile p.T403I ENST00000399464 NM_032442.2 403 aCc/aTc 0 +NEUROG2 UCSF GRCh37 4 113436633 113436633 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 13 113 0 ENST00000313341.3:c.-1-1G>A p.X1_splice ENST00000313341 NM_024019.3 0 +NF1 UCSF GRCh37 17 29559818 29559818 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 88 71 162 0 ENST00000358273.4:c.3415G>A p.Ala1139Thr p.A1139T ENST00000358273 NM_001042492.2 1139 Gca/Aca 0 +NF1 UCSF GRCh37 17 29654615 29654620 + inframe_deletion In_Frame_Del DEL AGAAAT AGAAAT - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 0 ENST00000358273.4:c.5367_5372del p.Glu1789_Ile1791delinsAsp p.E1789_I1791delinsD ENST00000358273 NM_001042492.2 1789 gaAGAAATc/gac 0 +NF2 UCSF GRCh37 22 30077550 30077550 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 37 141 0 ENST00000338641.4:c.1697C>T p.Ser566Phe p.S566F ENST00000338641 NM_000268.3 566 tCc/tTc 0 +NFASC UCSF GRCh37 1 204943842 204943842 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 85 0 ENST00000339876.6:c.1449C>T p.Asn483= p.N483= ENST00000339876 NM_001005388.2 483 aaC/aaT 0 +NFIL3 UCSF GRCh37 9 94172319 94172319 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 418 70 588 0 ENST00000297689.3:c.698G>A p.Arg233Lys p.R233K ENST00000297689 NM_005384.2 233 aGa/aAa 0 +NFKBIA UCSF GRCh37 14 35871683 35871683 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 18 174 0 ENST00000216797.5:c.823G>A p.Glu275Lys p.E275K ENST00000216797 NM_020529.2 275 Gaa/Aaa 0 +NFYA UCSF GRCh37 6 41051812 41051812 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 9 54 0 ENST00000341376.6:c.190G>A p.Val64Ile p.V64I ENST00000341376 NM_002505.4 64 Gtc/Atc 0 +NGDN UCSF GRCh37 14 23946745 23946745 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 23 131 0 ENST00000408901.3:c.904C>T p.Pro302Ser p.P302S ENST00000408901 NM_015514.1 302 Cct/Tct 0 +NHEJ1 UCSF GRCh37 2 220012486 220012486 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 22 86 0 ENST00000356853.5:c.422G>A p.Gly141Asp p.G141D ENST00000356853 NM_024782.2 141 gGc/gAc 0 +NID2 UCSF GRCh37 14 52477742 52477742 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 16 184 1 ENST00000216286.5:c.3574G>A p.Ala1192Thr p.A1192T ENST00000216286 NM_007361.3 1192 Gcc/Acc 0 +NIF3L1 UCSF GRCh37 2 201759992 201759992 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 23 273 0 ENST00000409020.1:c.605G>A p.Gly202Asp p.G202D ENST00000409020 202 gGt/gAt 0 +NIF3L1 UCSF GRCh37 2 201760089 201760089 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 21 210 0 ENST00000409020.1:c.702G>A p.Lys234= p.K234= ENST00000409020 234 aaG/aaA 0 +NIPBL UCSF GRCh37 5 37017264 37017264 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 21 163 0 ENST00000282516.8:c.4920G>A p.Gln1640= p.Q1640= ENST00000282516 NM_133433.3 1640 caG/caA 0 +NKD2 UCSF GRCh37 5 1034924 1034924 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 8 81 0 ENST00000296849.5:c.480C>T p.Asn160= p.N160= ENST00000296849 NM_033120.3 160 aaC/aaT 0 +NKIRAS1 UCSF GRCh37 3 23934754 23934754 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 379 54 523 0 ENST00000388759.3:c.411G>A p.Gln137= p.Q137= ENST00000388759 137 caG/caA 0 +NKPD1 UCSF GRCh37 19 45656002 45656002 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 35 160 0 ENST00000438936.2:c.1027G>A p.Asp343Asn p.D343N ENST00000438936 343 Gac/Aac 0 +NLRC4 UCSF GRCh37 2 32476057 32476057 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 41 375 0 ENST00000360906.5:c.876C>T p.Ala292= p.A292= ENST00000360906 NM_001199139.1 292 gcC/gcT 0 +NLRP5 UCSF GRCh37 19 56561867 56561867 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 16 189 0 ENST00000390649.3:c.3041G>A p.Ser1014Asn p.S1014N ENST00000390649 NM_153447.4 1014 aGc/aAc 0 +NLRP8 UCSF GRCh37 19 56466187 56466187 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 14 90 0 ENST00000291971.3:c.763A>G p.Ser255Gly p.S255G ENST00000291971 NM_176811.2 255 Agc/Ggc 0 +NLRP9 UCSF GRCh37 19 56249712 56249712 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 16 189 0 ENST00000332836.2:c.29G>A p.Gly10Asp p.G10D ENST00000332836 NM_176820.2 10 gGc/gAc 0 +NMB UCSF GRCh37 15 85201240 85201240 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 15 162 0 ENST00000360476.3:c.144C>T p.Asn48= p.N48= ENST00000360476 48 aaC/aaT 0 +NMT1 UCSF GRCh37 17 43138709 43138709 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 8 72 0 ENST00000258960.2:c.12G>A p.Glu4= p.E4= ENST00000258960 NM_021079.3 4 gaG/gaA 0 +NNMT UCSF GRCh37 11 114182874 114182874 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 10 106 0 ENST00000299964.3:c.470C>T p.Ala157Val p.A157V ENST00000299964 NM_006169.2 157 gCt/gTt 0 +NOB1 UCSF GRCh37 16 69776273 69776273 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 5 52 0 ENST00000268802.5:c.1201C>T p.Pro401Ser p.P401S ENST00000268802 NM_014062.2 401 Ccc/Tcc 0 +NOC4L UCSF GRCh37 12 132635830 132635830 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 391 57 522 0 ENST00000330579.1:c.990C>T p.Leu330= p.L330= ENST00000330579 NM_024078.1 330 ctC/ctT 0 +NOD2 UCSF GRCh37 16 50745218 50745218 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 272 50 303 0 ENST00000300589.2:c.1396G>A p.Ala466Thr p.A466T ENST00000300589 NM_022162.1 466 Gcg/Acg 0 +NOL11 UCSF GRCh37 17 65714129 65714129 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0024 P24_Rec2 Untested WXS Illumina HiSeq 65 12 86 0 ENST00000253247.4:c.66C>T p.Leu22= p.L22= ENST00000253247 NM_015462.3 22 ctC/ctT 0 +NOL12 UCSF GRCh37 22 38084991 38084991 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 22 123 0 ENST00000359114.4:c.373C>T p.Pro125Ser p.P125S ENST00000359114 NM_024313.2 125 Cca/Tca 0 +NOL6 UCSF GRCh37 9 33466700 33466700 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 37 0 ENST00000297990.4:c.1958G>A p.Ser653Asn p.S653N ENST00000297990 NM_022917.4 653 aGc/aAc 0 +NOTCH2 UCSF GRCh37 1 120510832 120510832 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 7 101 0 ENST00000256646.2:c.1132G>A p.Ala378Thr p.A378T ENST00000256646 NM_024408.3 378 Gca/Aca 0 +NOTCH3 UCSF GRCh37 19 15303236 15303236 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 17 115 0 ENST00000263388.2:c.292G>A p.Val98Met p.V98M ENST00000263388 NM_000435.2 98 Gtg/Atg 0 +NOX4 UCSF GRCh37 11 89073276 89073276 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 3 38 0 ENST00000263317.4:c.1401G>A p.Gln467= p.Q467= ENST00000263317 467 caG/caA 0 +NOXO1 UCSF GRCh37 16 2031163 2031163 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 14 112 0 ENST00000397280.4:c.18C>T p.Tyr6= p.Y6= ENST00000397280 6 taC/taT 0 +NPAS2 UCSF GRCh37 2 101607309 101607309 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 8 82 0 ENST00000335681.5:c.2086G>A p.Val696Ile p.V696I ENST00000335681 NM_002518.3 696 Gtc/Atc 0 +NPEPL1 UCSF GRCh37 20 57268858 57268858 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 36 272 0 ENST00000356091.6:c.216C>T p.Asn72= p.N72= ENST00000356091 NM_024663.3 72 aaC/aaT 0 +NPM1 UCSF GRCh37 5 170832397 170832397 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 40 0 ENST00000296930.5:c.761G>A p.Ser254Asn p.S254N ENST00000296930 NM_002520.6 254 aGt/aAt 0 +NPR1 UCSF GRCh37 1 153651984 153651984 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 12 73 0 ENST00000368680.3:c.400G>A p.Val134Ile p.V134I ENST00000368680 NM_000906.3 134 Gtc/Atc 0 +NPR3 UCSF GRCh37 5 32780919 32780919 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 19 144 0 ENST00000265074.8:c.1287G>A p.Gln429= p.Q429= ENST00000265074 NM_001204375.1 429 caG/caA 0 +NR1H2 UCSF GRCh37 19 50883108 50883108 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 39 245 0 ENST00000253727.5:c.999C>T p.Thr333= p.T333= ENST00000253727 NM_007121.5 333 acC/acT 0 +NRAP UCSF GRCh37 10 115364464 115364464 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 26 115 0 ENST00000359988.3:c.4131C>T p.Ser1377= p.S1377= ENST00000359988 NM_001261463.1 1377 agC/agT 0 +NRG1 UCSF GRCh37 8 32620750 32620750 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 27 204 0 ENST00000405005.3:c.1269-516C>T *423* ENST00000405005 0 +NRG1 UCSF GRCh37 8 31498022 31498022 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 11 91 0 ENST00000520407.1:c.522C>T p.Gly174= p.G174= ENST00000520407 NM_013962.2 174 ggC/ggT 0 +NRL UCSF GRCh37 14 24550553 24550553 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 8 83 0 ENST00000396997.1:c.606G>A p.Arg202= p.R202= ENST00000396997 202 cgG/cgA 0 +NRL UCSF GRCh37 14 24550568 24550568 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 6 70 0 ENST00000396997.1:c.591G>A p.Gln197= p.Q197= ENST00000396997 197 caG/caA 0 +NRXN1 UCSF GRCh37 2 50573959 50573959 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 10 56 0 ENST00000406316.2:c.3365-109851C>T *1122* ENST00000406316 NM_004801.4 0 +NRXN3 UCSF GRCh37 14 79181181 79181181 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 35 240 0 ENST00000554719.1:c.624C>T p.Tyr208= p.Y208= ENST00000554719 NM_004796.5 208 taC/taT 0 +NSDHL UCSF GRCh37 X 152037444 152037444 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 61 250 0 ENST00000370274.3:c.906C>T p.Tyr302= p.Y302= ENST00000370274 NM_015922.2 302 taC/taT 0 +NT5C2 UCSF GRCh37 10 104865512 104865512 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 18 391 1 ENST00000343289.5:c.340G>A p.Ala114Thr p.A114T ENST00000343289 NM_012229.4 114 Gcc/Acc 0 +NT5M UCSF GRCh37 17 17209926 17209926 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 9 83 0 ENST00000389022.4:c.337G>A p.Glu113Lys p.E113K ENST00000389022 NM_020201.3 113 Gaa/Aaa 0 +NTN4 UCSF GRCh37 12 96131783 96131786 + frameshift_variant Frame_Shift_Del DEL TTCA TTCA - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 7 0 ENST00000343702.4:c.722_725del p.Leu241ProfsTer159 p.L241Pfs*159 ENST00000343702 NM_021229.3 241 cTGAAc/cc 0 +NTN5 UCSF GRCh37 19 49164996 49164996 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 10 84 0 ENST00000270235.4:c.1408G>A p.Glu470Lys p.E470K ENST00000270235 NM_145807.1 470 Gag/Aag 0 +NTRK1 UCSF GRCh37 1 156845411 156845411 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 78 0 ENST00000524377.1:c.1454G>A p.Gly485Glu p.G485E ENST00000524377 NM_002529.3 485 gGg/gAg 0 +NTRK3 UCSF GRCh37 15 88678626 88678626 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 11 49 0 ENST00000360948.2:c.910C>T p.Pro304Ser p.P304S ENST00000360948 NM_001012338.2 304 Ccc/Tcc 0 +NTSR2 UCSF GRCh37 2 11802235 11802235 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 18 137 0 ENST00000306928.5:c.756C>T p.Ser252= p.S252= ENST00000306928 NM_012344.3 252 agC/agT 0 +NUDT6 UCSF GRCh37 4 123843525 123843525 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 18 131 0 ENST00000304430.5:c.203G>A p.Arg68His p.R68H ENST00000304430 NM_007083.4 68 cGc/cAc 0 +NUMA1 UCSF GRCh37 11 71725214 71725214 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 249 51 322 0 ENST00000393695.3:c.3335C>T p.Ala1112Val p.A1112V ENST00000393695 NM_006185.2 1112 gCt/gTt 0 +NUMA1 UCSF GRCh37 11 71730027 71730027 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 5 44 0 ENST00000393695.3:c.585-1G>A p.X195_splice ENST00000393695 NM_006185.2 0 +NUP133 UCSF GRCh37 1 229611474 229611474 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 9 150 0 ENST00000261396.3:c.1762C>T p.Pro588Ser p.P588S ENST00000261396 NM_018230.2 588 Cct/Tct 0 +NUP153 UCSF GRCh37 6 17626056 17626056 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 12 99 0 ENST00000262077.2:c.3884C>T p.Thr1295Ile p.T1295I ENST00000262077 NM_001278210.1 1295 aCc/aTc 0 +NUP153 UCSF GRCh37 6 17669248 17669248 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 8 91 0 ENST00000262077.2:c.1026G>A p.Arg342= p.R342= ENST00000262077 NM_001278210.1 342 agG/agA 0 +NUP210 UCSF GRCh37 3 13364863 13364863 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 17 204 0 ENST00000254508.5:c.4714G>A p.Ala1572Thr p.A1572T ENST00000254508 NM_024923.3 1572 Gct/Act 0 +NUP210L UCSF GRCh37 1 153995709 153995709 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 17 106 0 ENST00000368559.3:c.4187C>T p.Thr1396Ile p.T1396I ENST00000368559 NM_207308.2 1396 aCc/aTc 0 +NUP85 UCSF GRCh37 17 73208118 73208118 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 6 82 0 ENST00000245544.4:c.322G>A p.Val108Ile p.V108I ENST00000245544 NM_024844.3 108 Gtc/Atc 0 +NWD1 UCSF GRCh37 19 16870075 16870075 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 186 307 0 ENST00000552788.1:c.1809C>T p.Ser603= p.S603= ENST00000552788 603 tcC/tcT 0 +NXPH2 UCSF GRCh37 2 139428815 139428815 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 193 36 257 0 ENST00000272641.3:c.472G>A p.Val158Met p.V158M ENST00000272641 NM_007226.2 158 Gtg/Atg 0 +NXPH2 UCSF GRCh37 2 139429013 139429013 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 344 44 473 0 ENST00000272641.3:c.274G>A p.Glu92Lys p.E92K ENST00000272641 NM_007226.2 92 Gag/Aag 0 +OBSCN UCSF GRCh37 1 228548193 228548193 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 20 89 0 ENST00000422127.1:c.18662-2084C>T *6221* ENST00000422127 NM_001098623.2 0 +OBSCN UCSF GRCh37 1 228476009 228476009 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 19 113 0 ENST00000422127.1:c.10059C>T p.Ala3353= p.A3353= ENST00000422127 NM_001098623.2 3353 gcC/gcT 0 +OBSL1 UCSF GRCh37 2 220435838 220435838 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 38 80 0 ENST00000404537.1:c.117G>A p.Pro39= p.P39= ENST00000404537 NM_015311.2 39 ccG/ccA 0 +OBSL1 UCSF GRCh37 2 220435388 220435388 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 10 113 0 ENST00000404537.1:c.567C>T p.Gly189= p.G189= ENST00000404537 NM_015311.2 189 ggC/ggT 0 +ODZ1 UCSF GRCh37 X 123519840 123519840 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 16 49 0 ENST00000371130.3:c.5742C>T p.Val1914= p.V1914= ENST00000371130 NM_014253.3 1914 gtC/gtT 0 +ODZ4 UCSF GRCh37 11 78399263 78399263 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 27 269 0 ENST00000278550.7:c.5096G>A p.Ser1699Asn p.S1699N ENST00000278550 NM_001098816.2 1699 aGc/aAc 0 +OGFR UCSF GRCh37 20 61444254 61444254 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 7 68 0 ENST00000290291.6:c.1287G>A p.Gln429= p.Q429= ENST00000290291 NM_007346.2 429 caG/caA 0 +OLFML3 UCSF GRCh37 1 114524379 114524379 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.00188 P24_Rec2 Untested WXS Illumina HiSeq 193 34 265 0 ENST00000320334.4:c.1209G>A p.Glu403= p.E403= ENST00000320334 NM_020190.2 403 gaG/gaA 0 +OPA1 UCSF GRCh37 3 193335075 193335075 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 82 390 0 ENST00000392438.3:c.556+1G>A p.X186_splice ENST00000392438 NM_015560.2 0 +OPRD1 UCSF GRCh37 1 29189789 29189789 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 17 135 0 ENST00000234961.2:c.1113C>T p.Ala371= p.A371= ENST00000234961 NM_000911.3 371 gcC/gcT 0 +OR10A6 UCSF GRCh37 11 7950088 7950088 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 32 298 0 ENST00000309838.2:c.122G>A p.Gly41Glu p.G41E ENST00000309838 NM_001004461.1 41 gGa/gAa 0 +OR11L1 UCSF GRCh37 1 248004999 248004999 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 10 79 0 ENST00000355784.2:c.200C>T p.Ser67Phe p.S67F ENST00000355784 NM_001001959.1 67 tCc/tTc 0 +OR12D3 UCSF GRCh37 6 29342990 29342990 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 39 282 0 ENST00000396806.3:c.75C>T p.Phe25= p.F25= ENST00000396806 NM_030959.2 25 ttC/ttT 0 +OR13A1 UCSF GRCh37 10 45799010 45799010 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 7 92 0 ENST00000374401.2:c.861G>A p.Gly287= p.G287= ENST00000374401 287 ggG/ggA 0 +OR13C2 UCSF GRCh37 9 107367283 107367283 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 26 259 0 ENST00000542196.1:c.626C>T p.Thr209Ile p.T209I ENST00000542196 NM_001004481.1 209 aCa/aTa 0 +OR1N2 UCSF GRCh37 9 125316357 125316357 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 18 242 0 ENST00000373688.2:c.909C>T p.Asn303= p.N303= ENST00000373688 NM_001004457.1 303 aaC/aaT 0 +OR2C1 UCSF GRCh37 16 3406282 3406282 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 239 33 359 0 ENST00000304936.2:c.342G>A p.Leu114= p.L114= ENST00000304936 NM_012368.2 114 ctG/ctA 0 +OR2L13 UCSF GRCh37 1 248262866 248262866 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 447 63 721 0 ENST00000358120.2:c.189C>T p.Ser63= p.S63= ENST00000358120 63 agC/agT 0 +OR2T1 UCSF GRCh37 1 248570216 248570216 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 22 158 0 ENST00000366474.1:c.921C>T p.Tyr307= p.Y307= ENST00000366474 NM_030904.1 307 taC/taT 0 +OR4D2 UCSF GRCh37 17 56247215 56247215 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 383 62 617 0 ENST00000545221.1:c.199G>A p.Ala67Thr p.A67T ENST00000545221 NM_001004707.3 67 Gct/Act 0 +OR4L1 UCSF GRCh37 14 20528749 20528749 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 286 35 432 0 ENST00000315683.1:c.546C>T p.Pro182= p.P182= ENST00000315683 NM_001004717.1 182 ccC/ccT 0 +OR4N5 UCSF GRCh37 14 20612588 20612588 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 238 42 437 0 ENST00000333629.1:c.694G>A p.Gly232Arg p.G232R ENST00000333629 NM_001004724.1 232 Gga/Aga 0 +OR5C1 UCSF GRCh37 9 125551690 125551690 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 27 241 0 ENST00000373680.2:c.479C>T p.Ala160Val p.A160V ENST00000373680 NM_001001923.1 160 gCc/gTc 0 +OR5M3 UCSF GRCh37 11 56237418 56237418 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 33 0 ENST00000312240.2:c.556G>A p.Ala186Thr p.A186T ENST00000312240 NM_001004742.2 186 Gcc/Acc 0 +OR6B3 UCSF GRCh37 2 240984737 240984737 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 10 112 0 ENST00000319423.4:c.753C>T p.Phe251= p.F251= ENST00000319423 NM_173351.1 251 ttC/ttT 0 +OR6C2 UCSF GRCh37 12 55846226 55846226 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 316 40 497 0 ENST00000322678.1:c.229C>T p.Pro77Ser p.P77S ENST00000322678 NM_054105.1 77 Ccc/Tcc 0 +OR6Q1 UCSF GRCh37 11 57799189 57799189 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 278 40 422 0 ENST00000302622.3:c.765C>T p.Phe255= p.F255= ENST00000302622 NM_001005186.2 255 ttC/ttT 0 +OR7E24 UCSF GRCh37 19 9361896 9361896 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 9 77 0 ENST00000456448.1:c.177G>A p.Gly59= p.G59= ENST00000456448 NM_001079935.1 59 ggG/ggA 0 +OR8S1 UCSF GRCh37 12 48920197 48920197 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 299 53 433 0 ENST00000310194.1:c.783G>A p.Met261Ile p.M261I ENST00000310194 NM_001005203.2 261 atG/atA 0 +OR9Q2 UCSF GRCh37 11 57958336 57958336 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 359 64 496 0 ENST00000311591.3:c.374C>T p.Ala125Val p.A125V ENST00000311591 NM_001005283.2 125 gCc/gTc 0 +ORAI1 UCSF GRCh37 12 122079075 122079075 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 21 159 0 ENST00000330079.7:c.438C>T p.Ile146= p.I146= ENST00000330079 NM_032790.3 146 atC/atT 0 +ORMDL2 UCSF GRCh37 12 56212844 56212844 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 486 84 676 0 ENST00000243045.5:c.61G>A p.Gly21Ser p.G21S ENST00000243045 NM_014182.4 21 Ggc/Agc 0 +OSBPL2 UCSF GRCh37 20 60861698 60861698 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 123 20 137 0 ENST00000313733.3:c.1056G>A p.Glu352= p.E352= ENST00000313733 NM_144498.2 352 gaG/gaA 0 +OSMR UCSF GRCh37 5 38919054 38919054 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 507 210 847 0 ENST00000274276.3:c.1475G>A p.Ser492Asn p.S492N ENST00000274276 NM_003999.2 492 aGc/aAc 0 +OSMR UCSF GRCh37 5 38876472 38876472 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 26 279 0 ENST00000274276.3:c.243G>A p.Trp81Ter p.W81* ENST00000274276 NM_003999.2 81 tgG/tgA 0 +OTOF UCSF GRCh37 2 26699183 26699183 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 17 111 0 ENST00000272371.2:c.2679G>A p.Leu893= p.L893= ENST00000272371 NM_194248.2 893 ctG/ctA 0 +OTOP1 UCSF GRCh37 4 4199408 4199408 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 11 116 0 ENST00000296358.4:c.1153C>T p.Pro385Ser p.P385S ENST00000296358 NM_177998.1 385 Ccg/Tcg 0 +OTOR UCSF GRCh37 20 16729077 16729077 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 32 323 0 ENST00000246081.2:c.31G>A p.Gly11Ser p.G11S ENST00000246081 NM_020157.3 11 Ggt/Agt 0 +OTP UCSF GRCh37 5 76926188 76926188 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 8 51 0 ENST00000306422.3:c.879C>T p.Leu293= p.L293= ENST00000306422 NM_032109.2 293 ctC/ctT 0 +OTUD7A UCSF GRCh37 15 31851175 31851175 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 177 62 433 0 ENST00000307050.4:c.547G>A p.Ala183Thr p.A183T ENST00000307050 NM_130901.1 183 Gca/Aca 0 +OXER1 UCSF GRCh37 2 42990903 42990903 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 9 76 0 ENST00000378661.2:c.417C>T p.Phe139= p.F139= ENST00000378661 NM_148962.4 139 ttC/ttT 0 +OXNAD1 UCSF GRCh37 3 16343261 16343261 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 10 89 0 ENST00000285083.5:c.561C>T p.Ile187= p.I187= ENST00000285083 NM_138381.3 187 atC/atT 0 +P2RX5 UCSF GRCh37 17 3593904 3593904 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 252 45 409 0 ENST00000225328.5:c.431G>A p.Gly144Glu p.G144E ENST00000225328 NM_001204519.1 144 gGa/gAa 0 +PA2G4 UCSF GRCh37 12 56501380 56501380 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 19 175 0 ENST00000303305.6:c.469G>A p.Val157Ile p.V157I ENST00000303305 NM_006191.2 157 Gtc/Atc 0 +PADI4 UCSF GRCh37 1 17666209 17666209 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 9 41 0 ENST00000375448.4:c.553C>T p.Leu185= p.L185= ENST00000375448 NM_012387.2 185 Ctg/Ttg 0 +PAK1 UCSF GRCh37 11 77054972 77054972 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 27 251 0 ENST00000356341.3:c.890C>T p.Ala297Val p.A297V ENST00000356341 NM_002576.4 297 gCc/gTc 0 +PANK2 UCSF GRCh37 20 3888757 3888757 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 23 207 0 ENST00000316562.4:c.813G>A p.Lys271= p.K271= ENST00000316562 NM_153638.2 271 aaG/aaA 0 +PAPD7 UCSF GRCh37 5 6746357 6746357 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 21 257 0 ENST00000230859.6:c.526G>A p.Asp176Asn p.D176N ENST00000230859 NM_001171805.1 176 Gat/Aat 0 +PAQR8 UCSF GRCh37 6 52268237 52268237 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 315 53 431 0 ENST00000360726.3:c.226G>A p.Val76Met p.V76M ENST00000360726 76 Gtg/Atg 0 +PARD3B UCSF GRCh37 2 206165297 206165297 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 5 35 0 ENST00000406610.2:c.2229G>A p.Lys743= p.K743= ENST00000406610 NM_205863.3 743 aaG/aaA 0 +PARP10 UCSF GRCh37 8 145051948 145051948 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 20 91 0 ENST00000313028.7:c.2782G>A p.Val928Met p.V928M ENST00000313028 NM_032789.3 928 Gtg/Atg 0 +PATZ1 UCSF GRCh37 22 31741085 31741085 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 40 213 0 ENST00000266269.5:c.504C>T p.Ala168= p.A168= ENST00000266269 NM_014323.2 168 gcC/gcT 0 +PBX3 UCSF GRCh37 9 128725342 128725342 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 6 45 0 ENST00000373489.5:c.1174C>T p.Leu392Phe p.L392F ENST00000373489 NM_006195.5 392 Ctt/Ttt 0 +PCBP1 UCSF GRCh37 2 70315113 70315113 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 11 113 0 ENST00000303577.5:c.238G>A p.Glu80Lys p.E80K ENST00000303577 NM_006196.3 80 Gag/Aag 0 +PCCB UCSF GRCh37 3 135980893 135980893 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 11 70 0 ENST00000251654.4:c.529G>A p.Ala177Thr p.A177T ENST00000251654 NM_000532.4 177 Gca/Aca 0 +PCCB UCSF GRCh37 3 136046504 136046504 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 31 100 0 ENST00000251654.4:c.1328G>A p.Ser443Asn p.S443N ENST00000251654 NM_000532.4 443 aGc/aAc 0 +PCDH17 UCSF GRCh37 13 58207455 58207455 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 37 291 0 ENST00000377918.3:c.775G>A p.Gly259Ser p.G259S ENST00000377918 NM_001040429.2 259 Ggt/Agt 0 +PCDHA1 UCSF GRCh37 5 140166180 140166180 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 14 62 0 ENST00000504120.2:c.305G>A p.Cys102Tyr p.C102Y ENST00000504120 NM_018900.2 102 tGc/tAc 0 +PCDHA1 UCSF GRCh37 5 140167511 140167511 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 4 27 0 ENST00000504120.2:c.1636G>A p.Gly546Ser p.G546S ENST00000504120 NM_018900.2 546 Ggc/Agc 0 +PCDHA4 UCSF GRCh37 5 140187587 140187587 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 208 30 346 0 ENST00000530339.1:c.815G>A p.Gly272Glu p.G272E ENST00000530339 NM_018907.2 272 gGa/gAa 0 +PCDHGA2 UCSF GRCh37 5 140720468 140720468 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 8 97 0 ENST00000394576.2:c.1930G>A p.Val644Met p.V644M ENST00000394576 NM_018915.2 644 Gtg/Atg 0 +PCDHGA2 UCSF GRCh37 5 140720761 140720761 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 22 80 0 ENST00000394576.2:c.2223G>A p.Val741= p.V741= ENST00000394576 NM_018915.2 741 gtG/gtA 0 +PCDHGB4 UCSF GRCh37 5 140769026 140769026 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 16 137 0 ENST00000519479.1:c.1575C>T p.Ala525= p.A525= ENST00000519479 NM_003736.2 525 gcC/gcT 0 +PCDHGB6 UCSF GRCh37 5 140789693 140789693 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 10 94 0 ENST00000520790.1:c.1924C>T p.Leu642= p.L642= ENST00000520790 NM_018926.2 642 Ctg/Ttg 0 +PCK1 UCSF GRCh37 20 56138627 56138627 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 4 28 0 ENST00000319441.4:c.805G>A p.Gly269Ser p.G269S ENST00000319441 NM_002591.3 269 Ggt/Agt 0 +PCLO UCSF GRCh37 7 82583161 82583161 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 12 124 0 ENST00000333891.9:c.7108G>A p.Glu2370Lys p.E2370K ENST00000333891 NM_033026.5 2370 Gaa/Aaa 0 +PCNT UCSF GRCh37 21 47805859 47805859 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 12 66 0 ENST00000359568.5:c.3425C>T p.Ser1142Phe p.S1142F ENST00000359568 NM_006031.5 1142 tCc/tTc 0 +PCNX UCSF GRCh37 14 71572113 71572113 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 10 65 0 ENST00000304743.2:c.6257G>A p.Gly2086Glu p.G2086E ENST00000304743 NM_014982.2 2086 gGa/gAa 0 +PDCD6IP UCSF GRCh37 3 33853593 33853593 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 285 37 427 0 ENST00000307296.3:c.239C>T p.Pro80Leu p.P80L ENST00000307296 80 cCc/cTc 0 +PDCD6IP UCSF GRCh37 3 33896693 33896693 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 6 20 0 ENST00000307296.3:c.2061C>T p.Phe687= p.F687= ENST00000307296 687 ttC/ttT 0 +PDE2A UCSF GRCh37 11 72292464 72292464 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 9 39 0 ENST00000334456.5:c.1982C>T p.Ala661Val p.A661V ENST00000334456 NM_002599.4 661 gCc/gTc 0 +PDE2A UCSF GRCh37 11 72291938 72291938 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 18 90 0 ENST00000334456.5:c.2125G>C p.Val709Leu p.V709L ENST00000334456 NM_002599.4 709 Gtg/Ctg 0 +PDE8A UCSF GRCh37 15 85610248 85610248 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 15 148 0 ENST00000310298.4:c.247C>T p.Leu83Phe p.L83F ENST00000310298 83 Ctt/Ttt 0 +PDGFB UCSF GRCh37 22 39639950 39639950 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 20 124 0 ENST00000331163.6:c.19C>T p.Leu7Phe p.L7F ENST00000331163 NM_002608.2 7 Ctc/Ttc 0 +PDGFC UCSF GRCh37 4 157689065 157689065 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 23 283 0 ENST00000502773.1:c.781G>A p.Glu261Lys p.E261K ENST00000502773 NM_016205.2 261 Gaa/Aaa 0 +PDHA2 UCSF GRCh37 4 96762127 96762127 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 17 71 0 ENST00000295266.4:c.826G>A p.Gly276Arg p.G276R ENST00000295266 NM_005390.4 276 Ggg/Agg 0 +PDHB UCSF GRCh37 3 58416454 58416454 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 13 89 0 ENST00000302746.6:c.519G>A p.Lys173= p.K173= ENST00000302746 NM_000925.3 173 aaG/aaA 0 +PDHX UCSF GRCh37 11 34938345 34938345 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 6 50 0 ENST00000227868.4:c.143G>A p.Ser48Asn p.S48N ENST00000227868 48 aGc/aAc 0 +PDIA5 UCSF GRCh37 3 122808018 122808018 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 13 105 0 ENST00000316218.7:c.46G>A p.Val16Ile p.V16I ENST00000316218 NM_006810.3 16 Gtc/Atc 0 +PDLIM3 UCSF GRCh37 4 186435434 186435434 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 28 284 0 ENST00000284770.5:c.388G>A p.Gly130Ser p.G130S ENST00000284770 NM_014476.5 130 Ggc/Agc 0 +PDXDC1 UCSF GRCh37 16 15125643 15125643 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 7 94 0 ENST00000396410.4:c.1451G>A p.Ser484Asn p.S484N ENST00000396410 NM_015027.2 484 aGc/aAc 0 +PDZD7 UCSF GRCh37 10 102778682 102778682 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 6 89 0 ENST00000370215.3:c.1221C>T p.Arg407= p.R407= ENST00000370215 NM_024895.4 407 cgC/cgT 0 +PDZRN4 UCSF GRCh37 12 41967428 41967428 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 240 40 356 0 ENST00000402685.2:c.2847C>T p.His949= p.H949= ENST00000402685 NM_001164595.1 949 caC/caT 0 +PEAK1 UCSF GRCh37 15 77425452 77425452 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 91 275 0 ENST00000312493.4:c.3972G>A p.Trp1324Ter p.W1324* ENST00000312493 NM_024776.3 1324 tgG/tgA 0 +PEBP1 UCSF GRCh37 12 118577290 118577290 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 7 98 0 ENST00000261313.2:c.280G>A p.Gly94Ser p.G94S ENST00000261313 NM_002567.2 94 Ggc/Agc 0 +PEX6 UCSF GRCh37 6 42941759 42941759 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 390 71 524 0 ENST00000304611.8:c.1112G>A p.Ser371Asn p.S371N ENST00000304611 NM_000287.3 371 aGt/aAt 0 +PFKFB4 UCSF GRCh37 3 48587613 48587613 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 28 229 0 ENST00000232375.3:c.152G>A p.Gly51Asp p.G51D ENST00000232375 NM_004567.2 51 gGc/gAc 0 +PGBD2 UCSF GRCh37 1 249211522 249211522 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 370 51 540 0 ENST00000329291.5:c.739C>T p.Pro247Ser p.P247S ENST00000329291 NM_170725.2 247 Cct/Tct 0 +PGM2 UCSF GRCh37 4 37831716 37831716 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 12 91 0 ENST00000381967.4:c.212C>T p.Ser71Phe p.S71F ENST00000381967 NM_018290.3 71 tCt/tTt 0 +PHACTR3 UCSF GRCh37 20 58152623 58152623 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 15 120 0 ENST00000359926.3:c.60C>T p.Gly20= p.G20= ENST00000359926 NM_001199505.1 20 ggC/ggT 0 +PHACTR3 UCSF GRCh37 20 58330317 58330317 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 30 181 0 ENST00000371015.1:c.439C>T p.Leu147= p.L147= ENST00000371015 NM_080672.4 147 Ctg/Ttg 0 +PHF1 UCSF GRCh37 6 33382758 33382758 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 7 27 0 ENST00000374516.3:c.1076G>A p.Gly359Glu p.G359E ENST00000374516 NM_024165.2 359 gGa/gAa 0 +PHF12 UCSF GRCh37 17 27251136 27251136 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 30 257 0 ENST00000332830.4:c.506C>T p.Ser169Phe p.S169F ENST00000332830 NM_001033561.1 169 tCc/tTc 0 +PHF12 UCSF GRCh37 17 27240296 27240296 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 17 85 0 ENST00000332830.4:c.1294-1G>A p.X432_splice ENST00000332830 NM_001033561.1 0 +PHF19 UCSF GRCh37 9 123620309 123620309 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 30 256 0 ENST00000373896.3:c.1656G>A p.Gly552= p.G552= ENST00000373896 NM_015651.1 552 ggG/ggA 0 +PHF2 UCSF GRCh37 9 96407928 96407928 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 19 102 0 ENST00000359246.4:c.317C>T p.Ala106Val p.A106V ENST00000359246 NM_005392.3 106 gCc/gTc 0 +PHF20 UCSF GRCh37 20 34458943 34458943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 19 142 0 ENST00000374012.3:c.989G>A p.Arg330Lys p.R330K ENST00000374012 330 aGg/aAg 0 +PHF8 UCSF GRCh37 X 54043128 54043128 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 23 81 0 ENST00000357988.5:c.604G>A p.Ala202Thr p.A202T ENST00000357988 NM_001184896.1 202 Gct/Act 0 +PHGDH UCSF GRCh37 1 120254733 120254733 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 22 138 0 ENST00000369409.4:c.88G>A p.Val30Met p.V30M ENST00000369409 NM_006623.3 30 Gtg/Atg 0 +PHKA2 UCSF GRCh37 X 18912438 18912438 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 16 132 0 ENST00000379942.4:c.3421G>A p.Val1141Met p.V1141M ENST00000379942 NM_000292.2 1141 Gtg/Atg 0 +PHKG1 UCSF GRCh37 7 56149333 56149333 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 25 0 ENST00000297373.2:c.908G>A p.Gly303Glu p.G303E ENST00000297373 NM_006213.4 303 gGg/gAg 0 +PI4KB UCSF GRCh37 1 151280276 151280276 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 13 89 0 ENST00000368873.1:c.956C>T p.Pro319Leu p.P319L ENST00000368873 319 cCt/cTt 0 +PIAS3 UCSF GRCh37 1 145578398 145578398 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 315 49 462 0 ENST00000393045.2:c.361C>T p.Gln121Ter p.Q121* ENST00000393045 NM_006099.3 121 Cag/Tag 0 +PIEZO2 UCSF GRCh37 18 10691261 10691261 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 12 113 0 ENST00000503781.3:c.6972C>T p.Thr2324= p.T2324= ENST00000503781 NM_022068.2 2324 acC/acT 0 +PIGL UCSF GRCh37 17 16120652 16120652 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 27 205 0 ENST00000225609.5:c.112G>A p.Gly38Arg p.G38R ENST00000225609 NM_004278.3 38 Gga/Aga 0 +PIGZ UCSF GRCh37 3 196674425 196674425 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 7 54 0 ENST00000412723.1:c.1343C>T p.Ala448Val p.A448V ENST00000412723 NM_025163.3 448 gCc/gTc 0 +PIK3C2A UCSF GRCh37 11 17172087 17172087 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 23 262 1 ENST00000265970.7:c.1285G>A p.Asp429Asn p.D429N ENST00000265970 NM_002645.2 429 Gac/Aac 0 +PIK3R1 UCSF GRCh37 5 67522637 67522637 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 132 23 196 0 ENST00000521381.1:c.134G>A p.Gly45Glu p.G45E ENST00000521381 NM_181523.2 45 gGa/gAa 0 +PIK3R4 UCSF GRCh37 3 130398229 130398229 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 66 198 0 ENST00000356763.3:c.4007C>T p.Ala1336Val p.A1336V ENST00000356763 NM_014602.2 1336 gCc/gTc 0 +PITPNM3 UCSF GRCh37 17 6406878 6406878 + synonymous_variant Silent SNP C C A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 12 56 0 ENST00000262483.8:c.243G>T p.Pro81= p.P81= ENST00000262483 NM_031220.3 81 ccG/ccT 0 +PKD1 UCSF GRCh37 16 2142185 2142185 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 12 96 0 ENST00000262304.4:c.11274C>T p.Leu3758= p.L3758= ENST00000262304 NM_001009944.2 3758 ctC/ctT 0 +PKHD1L1 UCSF GRCh37 8 110535461 110535461 + splice_acceptor_variant Splice_Site SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 15 54 0 ENST00000378402.5:c.12331-1G>T p.X4111_splice ENST00000378402 NM_177531.4 0 +PKIG UCSF GRCh37 20 43243344 43243344 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 8 45 0 ENST00000349959.3:c.147G>A p.Gly49= p.G49= ENST00000349959 49 ggG/ggA 0 +PKN2 UCSF GRCh37 1 89298952 89298952 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 33 300 0 ENST00000370521.3:c.2776G>A p.Asp926Asn p.D926N ENST00000370521 NM_006256.2 926 Gac/Aac 0 +PKP1 UCSF GRCh37 1 201292273 201292273 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 53 0 ENST00000263946.3:c.1699G>A p.Ala567Thr p.A567T ENST00000263946 NM_000299.3 567 Gcc/Acc 0 +PKP4 UCSF GRCh37 2 159498999 159498999 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 41 0 ENST00000389759.3:c.1697T>C p.Val566Ala p.V566A ENST00000389759 NM_003628.3 566 gTg/gCg 0 +PLB1 UCSF GRCh37 2 28823694 28823694 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 12 79 0 ENST00000327757.5:c.2493C>T p.Val831= p.V831= ENST00000327757 NM_153021.4 831 gtC/gtT 0 +PLBD2 UCSF GRCh37 12 113806940 113806940 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 20 186 0 ENST00000280800.3:c.310G>A p.Gly104Ser p.G104S ENST00000280800 NM_173542.3 104 Ggc/Agc 0 +PLCD3 UCSF GRCh37 17 43194151 43194151 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 6 44 0 ENST00000322765.5:c.1261C>T p.Leu421= p.L421= ENST00000322765 NM_133373.3 421 Ctg/Ttg 0 +PLCD4 UCSF GRCh37 2 219496999 219496999 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 3 31 0 ENST00000417849.1:c.1413C>T p.Pro471= p.P471= ENST00000417849 471 ccC/ccT 0 +PLCH2 UCSF GRCh37 1 2435776 2435776 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.0138 P24_Rec2 Untested WXS Illumina HiSeq 211 36 249 0 ENST00000378486.3:c.3375G>A p.Thr1125= p.T1125= ENST00000378486 NM_014638.2 1125 acG/acA 0 +PLD5 UCSF GRCh37 1 242271036 242271036 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 19 136 0 ENST00000442594.2:c.900G>A p.Thr300= p.T300= ENST00000442594 NM_152666.2 300 acG/acA 0 +PLEC UCSF GRCh37 8 144996554 144996554 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 6 61 0 ENST00000322810.4:c.7846G>A p.Val2616Met p.V2616M ENST00000322810 NM_201380.2 2616 Gtg/Atg 0 +PLEC UCSF GRCh37 8 145003922 145003922 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 82 0 ENST00000322810.4:c.3226G>A p.Asp1076Asn p.D1076N ENST00000322810 NM_201380.2 1076 Gac/Aac 0 +PLEKHA7 UCSF GRCh37 11 16823347 16823347 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 8 42 0 ENST00000355661.3:c.2175G>A p.Val725= p.V725= ENST00000355661 725 gtG/gtA 0 +PLEKHA8 UCSF GRCh37 7 30118238 30118238 + missense_variant Missense_Mutation SNP T T G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 61 170 0 ENST00000449726.1:c.1395T>G p.Asp465Glu p.D465E ENST00000449726 NM_001197027.1 465 gaT/gaG 0 +PLEKHG4 UCSF GRCh37 16 67318226 67318226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 22 212 0 ENST00000360461.5:c.1558G>A p.Glu520Lys p.E520K ENST00000360461 NM_001129727.1 520 Gag/Aag 0 +PLEKHG5 UCSF GRCh37 1 6579521 6579521 + downstream_gene_variant 3'Flank SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 17 141 0 ENST00000377705 NM_024654.4 0 +PLEKHH1 UCSF GRCh37 14 68029130 68029130 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 28 195 0 ENST00000329153.5:c.782G>A p.Arg261Lys p.R261K ENST00000329153 NM_020715.2 261 aGa/aAa 0 +PLEKHJ1 UCSF GRCh37 19 2235921 2235921 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 23 134 0 ENST00000326631.2:c.162+1G>A p.X54_splice ENST00000326631 NM_018049.1 0 +PLEKHM1 UCSF GRCh37 17 43555292 43555292 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 34 0 ENST00000430334.3:c.270G>A p.Trp90Ter p.W90* ENST00000430334 NM_014798.2 90 tgG/tgA 0 +PLEKHM2 UCSF GRCh37 1 16054173 16054173 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 13 104 0 ENST00000375799.3:c.1606G>A p.Glu536Lys p.E536K ENST00000375799 NM_015164.2 536 Gag/Aag 0 +PLIN4 UCSF GRCh37 19 4512416 4512416 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 79 259 0 ENST00000301286.3:c.1514C>T p.Thr505Ile p.T505I ENST00000301286 NM_001080400.1 505 aCc/aTc 0 +PLIN4 UCSF GRCh37 19 4504779 4504779 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 16 75 0 ENST00000301286.3:c.3766C>T p.Leu1256= p.L1256= ENST00000301286 NM_001080400.1 1256 Ctg/Ttg 0 +PLXNA2 UCSF GRCh37 1 208272276 208272276 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 14 83 0 ENST00000367033.3:c.1646C>T p.Pro549Leu p.P549L ENST00000367033 NM_025179.3 549 cCt/cTt 0 +PLXNA4 UCSF GRCh37 7 131888179 131888179 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 16 117 0 ENST00000321063.4:c.2299-1G>A p.X767_splice ENST00000321063 NM_020911.1 0 +PLXNB3 UCSF GRCh37 X 153040007 153040007 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 31 132 0 ENST00000361971.5:c.3811C>T p.Leu1271Phe p.L1271F ENST00000361971 NM_005393.2 1271 Ctc/Ttc 0 +PLXNB3 UCSF GRCh37 X 153041605 153041605 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 6 35 0 ENST00000361971.5:c.4665G>A p.Val1555= p.V1555= ENST00000361971 NM_005393.2 1555 gtG/gtA 0 +PNPLA6 UCSF GRCh37 19 7616255 7616255 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 12 82 0 ENST00000414982.3:c.2219C>T p.Thr740Ile p.T740I ENST00000414982 NM_001166111.1 740 aCc/aTc 0 +PNPO UCSF GRCh37 17 46023984 46023984 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 23 127 0 ENST00000225573.4:c.622G>A p.Gly208Ser p.G208S ENST00000225573 NM_018129.3 208 Ggc/Agc 0 +PODXL UCSF GRCh37 7 131196090 131196090 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 19 142 0 ENST00000378555.3:c.203C>T p.Thr68Ile p.T68I ENST00000378555 68 aCt/aTt 0 +POGLUT1 UCSF GRCh37 3 119196263 119196263 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 6 36 0 ENST00000295588.4:c.424G>A p.Glu142Lys p.E142K ENST00000295588 NM_152305.2 142 Gag/Aag 0 +POLD1 UCSF GRCh37 19 50918726 50918726 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 13 83 0 ENST00000440232.2:c.2596G>A p.Asp866Asn p.D866N ENST00000440232 NM_002691.3 866 Gac/Aac 0 +POLE UCSF GRCh37 12 133250267 133250267 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 30 252 0 ENST00000320574.5:c.1253C>T p.Pro418Leu p.P418L ENST00000320574 NM_006231.2 418 cCt/cTt 0 +POLG UCSF GRCh37 15 89859994 89859994 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 114 349 0 ENST00000268124.5:c.3708G>A p.Gln1236= p.Q1236= ENST00000268124 NM_001126131.1 1236 caG/caA 0 +POLK UCSF GRCh37 5 74886260 74886260 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 11 85 0 ENST00000241436.4:c.1351C>T p.Leu451Phe p.L451F ENST00000241436 NM_016218.2 451 Ctt/Ttt 0 +POLQ UCSF GRCh37 3 121238772 121238772 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 4 41 0 ENST00000264233.5:c.1414C>T p.Leu472Phe p.L472F ENST00000264233 NM_199420.3 472 Ctt/Ttt 0 +POLQ UCSF GRCh37 3 121192275 121192275 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 33 296 0 ENST00000264233.5:c.6465G>A p.Lys2155= p.K2155= ENST00000264233 NM_199420.3 2155 aaG/aaA 0 +POLR1A UCSF GRCh37 2 86276299 86276299 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 8 65 0 ENST00000263857.6:c.2459C>T p.Thr820Ile p.T820I ENST00000263857 820 aCc/aTc 0 +POLR3B UCSF GRCh37 12 106786810 106786810 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 19 173 1 ENST00000228347.4:c.725C>T p.Ala242Val p.A242V ENST00000228347 NM_018082.5 242 gCc/gTc 0 +POLR3C UCSF GRCh37 1 145608438 145608438 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 253 42 345 0 ENST00000334163.3:c.369G>A p.Lys123= p.K123= ENST00000334163 NM_006468.6 123 aaG/aaA 0 +POLR3G UCSF GRCh37 5 89791543 89791543 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 198 22 350 0 ENST00000399107.1:c.297G>A p.Trp99Ter p.W99* ENST00000399107 NM_006467.2 99 tgG/tgA 0 +POLR3GL UCSF GRCh37 1 145457265 145457265 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 21 182 0 ENST00000369314.1:c.427G>A p.Asp143Asn p.D143N ENST00000369314 NM_032305.1 143 Gat/Aat 0 +POLRMT UCSF GRCh37 19 619040 619040 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 30 0 ENST00000588649.2:c.3224G>A p.Gly1075Asp p.G1075D ENST00000588649 NM_005035.3 1075 gGc/gAc 0 +PORCN UCSF GRCh37 X 48370884 48370884 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 17 64 0 ENST00000326194.6:c.544G>A p.Gly182Ser p.G182S ENST00000326194 NM_203475.1 182 Ggc/Agc 0 +POU1F1 UCSF GRCh37 3 87313588 87313588 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 17 164 0 ENST00000350375.2:c.289C>T p.Leu97Phe p.L97F ENST00000350375 NM_000306.2 97 Ctt/Ttt 0 +POU2AF1 UCSF GRCh37 11 111225225 111225225 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 7 61 0 ENST00000393067.3:c.532C>T p.Pro178Ser p.P178S ENST00000393067 NM_006235.2 178 Ccg/Tcg 0 +POU2F1 UCSF GRCh37 1 167358932 167358932 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 88 267 0 ENST00000541643.3:c.852C>T p.Asp284= p.D284= ENST00000541643 284 gaC/gaT 0 +PPAP2C UCSF GRCh37 19 281472 281472 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 8 63 0 ENST00000434325.2:c.615G>A p.Leu205= p.L205= ENST00000434325 205 ctG/ctA 0 +PPAPDC2 UCSF GRCh37 9 4662876 4662876 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 14 136 0 ENST00000381883.2:c.501G>A p.Met167Ile p.M167I ENST00000381883 NM_203453.3 167 atG/atA 0 +PPARGC1A UCSF GRCh37 4 23814383 23814383 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 536 93 841 0 ENST00000264867.2:c.2006G>A p.Arg669Lys p.R669K ENST00000264867 NM_013261.3 669 aGg/aAg 0 +PPCS UCSF GRCh37 1 42925543 42925543 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 20 201 0 ENST00000372561.3:c.882G>A p.Lys294= p.K294= ENST00000372561 NM_024664.2 294 aaG/aaA 0 +PPIC UCSF GRCh37 5 122359692 122359692 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 34 279 0 ENST00000306442.4:c.517G>A p.Val173Met p.V173M ENST00000306442 NM_000943.4 173 Gtg/Atg 0 +PPIG UCSF GRCh37 2 170493243 170493243 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 7 77 0 ENST00000260970.3:c.1475G>A p.Arg492Lys p.R492K ENST00000260970 NM_004792.2 492 aGg/aAg 0 +PPL UCSF GRCh37 16 4934223 4934223 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 42 276 0 ENST00000345988.2:c.4433G>A p.Gly1478Glu p.G1478E ENST00000345988 NM_002705.4 1478 gGg/gAg 0 +PPL UCSF GRCh37 16 4945402 4945402 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 7 64 0 ENST00000345988.2:c.1102G>A p.Glu368Lys p.E368K ENST00000345988 NM_002705.4 368 Gag/Aag 0 +PPL UCSF GRCh37 16 4935581 4935581 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 477 61 577 0 ENST00000345988.2:c.3075C>T p.Gly1025= p.G1025= ENST00000345988 NM_002705.4 1025 ggC/ggT 0 +PPP1R10 UCSF GRCh37 6 30569755 30569755 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 11 81 0 ENST00000376511.2:c.2671G>A p.Gly891Arg p.G891R ENST00000376511 NM_002714.3 891 Ggg/Agg 0 +PPP1R12A UCSF GRCh37 12 80199970 80199970 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 48 0 ENST00000261207.5:c.1799C>T p.Ser600Phe p.S600F ENST00000261207 NM_001143885.1 600 tCt/tTt 0 +PPP1R12C UCSF GRCh37 19 55603275 55603275 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 4 17 0 ENST00000263433.3:c.2163G>A p.Arg721= p.R721= ENST00000263433 NM_017607.3 721 agG/agA 0 +PPP1R1B UCSF GRCh37 17 37791937 37791937 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 19 113 0 ENST00000254079.4:c.523G>A p.Asp175Asn p.D175N ENST00000254079 NM_032192.3 175 Gat/Aat 0 +PPP1R1B UCSF GRCh37 17 37792068 37792068 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 29 274 0 ENST00000254079.4:c.566-1G>A p.X189_splice ENST00000254079 NM_032192.3 0 +PPP1R9A UCSF GRCh37 7 94539523 94539523 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 19 154 0 ENST00000340694.4:c.98C>T p.Thr33Ile p.T33I ENST00000340694 NM_001166163.1 33 aCc/aTc 0 +PPP2R1A UCSF GRCh37 19 52723488 52723488 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 25 180 0 ENST00000322088.6:c.1349G>A p.Trp450Ter p.W450* ENST00000322088 NM_014225.5 450 tGg/tAg 0 +PPP4R1 UCSF GRCh37 18 9550083 9550083 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 14 165 0 ENST00000400556.3:c.2514G>A p.Trp838Ter p.W838* ENST00000400556 NM_001042388.2 838 tgG/tgA 0 +PPP6R2 UCSF GRCh37 22 50860692 50860692 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 10 114 0 ENST00000216061.5:c.855C>T p.Gly285= p.G285= ENST00000216061 285 ggC/ggT 0 +PQLC1 UCSF GRCh37 18 77679347 77679347 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 12 36 0 ENST00000397778.2:c.445T>C p.Cys149Arg p.C149R ENST00000397778 NM_025078.4 149 Tgc/Cgc 0 +PQLC2 UCSF GRCh37 1 19652012 19652012 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 18 94 0 ENST00000375153.3:c.318C>T p.Val106= p.V106= ENST00000375153 NM_001040125.1 106 gtC/gtT 0 +PRAM1 UCSF GRCh37 19 8563584 8563584 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 19 178 0 ENST00000423345.4:c.1108C>T p.Pro370Ser p.P370S ENST00000423345 370 Ccg/Tcg 0 +PRB2 UCSF GRCh37 12 11546488 11546488 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 4 25 0 ENST00000389362.4:c.524C>T p.Ser175Phe p.S175F ENST00000389362 NM_006248.3 175 tCt/tTt 0 +PRDM1 UCSF GRCh37 6 106547225 106547225 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 9 75 0 ENST00000369096.4:c.462G>A p.Glu154= p.E154= ENST00000369096 NM_001198.3 154 gaG/gaA 0 +PRELID2 UCSF GRCh37 5 145198978 145198978 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 15 160 0 ENST00000334744.4:c.208-1G>A p.X70_splice ENST00000334744 NM_182960.2 0 +PREX1 UCSF GRCh37 20 47274678 47274678 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 251 686 0 ENST00000371941.3:c.1970C>T p.Ala657Val p.A657V ENST00000371941 NM_020820.3 657 gCt/gTt 0 +PRKAA2 UCSF GRCh37 1 57169883 57169883 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 377 58 544 0 ENST00000371244.4:c.1028C>T p.Ala343Val p.A343V ENST00000371244 NM_006252.3 343 gCc/gTc 0 +PRKAR2B UCSF GRCh37 7 106793633 106793633 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 18 214 0 ENST00000265717.4:c.855C>T p.Arg285= p.R285= ENST00000265717 NM_002736.2 285 cgC/cgT 0 +PRKCE UCSF GRCh37 2 46411943 46411943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 252 148 555 0 ENST00000306156.3:c.2137G>A p.Asp713Asn p.D713N ENST00000306156 NM_005400.2 713 Gac/Aac 0 +PRKCE UCSF GRCh37 2 45879539 45879539 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 6 41 0 ENST00000306156.3:c.300C>T p.Ile100= p.I100= ENST00000306156 NM_005400.2 100 atC/atT 0 +PRKD2 UCSF GRCh37 19 47207845 47207845 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 28 163 0 ENST00000291281.4:c.573C>T p.Ala191= p.A191= ENST00000291281 191 gcC/gcT 0 +PRKDC UCSF GRCh37 8 48746825 48746825 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 17 118 0 ENST00000314191.2:c.8081C>T p.Ser2694Leu p.S2694L ENST00000314191 NM_006904.6 2694 tCa/tTa 0 +PRKDC UCSF GRCh37 8 48686847 48686847 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 20 204 0 ENST00000314191.2:c.12271C>T p.Gln4091Ter p.Q4091* ENST00000314191 NM_006904.6 4091 Caa/Taa 0 +PRKX UCSF GRCh37 X 3631222 3631222 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 4 14 0 ENST00000262848.5:c.73G>A p.Asp25Asn p.D25N ENST00000262848 NM_005044.4 25 Gac/Aac 0 +PRMT5 UCSF GRCh37 14 23393582 23393582 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 27 216 0 ENST00000324366.8:c.1096G>A p.Ala366Thr p.A366T ENST00000324366 NM_006109.3 366 Gca/Aca 0 +PRMT6 UCSF GRCh37 1 107599844 107599844 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 18 144 0 ENST00000370078.1:c.507C>T p.Ser169= p.S169= ENST00000370078 169 tcC/tcT 0 +PRMT7 UCSF GRCh37 16 68349966 68349966 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 3 78 0 ENST00000339507.5:c.84G>A p.Gln28= p.Q28= ENST00000339507 28 caG/caA 0 +PRODH2 UCSF GRCh37 19 36303727 36303727 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 10 96 0 ENST00000301175.3:c.209G>A p.Gly70Glu p.G70E ENST00000301175 NM_021232.1 70 gGa/gAa 0 +PRODH2 UCSF GRCh37 19 36303717 36303717 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 17 101 0 ENST00000301175.3:c.219G>A p.Gln73= p.Q73= ENST00000301175 NM_021232.1 73 caG/caA 0 +PROS1 UCSF GRCh37 3 93595954 93595954 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 28 222 0 ENST00000394236.3:c.1726G>A p.Glu576Lys p.E576K ENST00000394236 NM_000313.3 576 Gaa/Aaa 0 +PROSER1 UCSF GRCh37 13 39586978 39586978 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 9 57 0 ENST00000352251.3:c.2411C>T p.Pro804Leu p.P804L ENST00000352251 NM_025138.4 804 cCc/cTc 0 +PROX1 UCSF GRCh37 1 214170574 214170574 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 17 98 0 ENST00000261454.4:c.696G>A p.Lys232= p.K232= ENST00000261454 232 aaG/aaA 0 +PRPH UCSF GRCh37 12 49690754 49690754 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 13 36 0 ENST00000257860.4:c.785C>T p.Thr262Met p.T262M ENST00000257860 NM_006262.3 262 aCg/aTg 0 +PRR11 UCSF GRCh37 17 57272127 57272127 + synonymous_variant Silent SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 32 91 0 ENST00000262293.4:c.655T>C p.Leu219= p.L219= ENST00000262293 NM_018304.3 219 Tta/Cta 0 +PRR12 UCSF GRCh37 19 50098074 50098074 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 36 364 0 ENST00000418929.2:c.482C>T p.Pro161Leu p.P161L ENST00000418929 NM_020719.1 161 cCc/cTc 0 +PRR14L UCSF GRCh37 22 32081545 32081545 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 360 65 583 1 ENST00000327423.6:c.6424G>A p.Glu2142Lys p.E2142K ENST00000327423 NM_173566.2 2142 Gaa/Aaa 0 +PRR5L UCSF GRCh37 11 36458955 36458955 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 68 534 0 ENST00000378867.3:c.373C>T p.Leu125= p.L125= ENST00000378867 NM_024841.4 125 Ctg/Ttg 0 +PRRC2A UCSF GRCh37 6 31593028 31593028 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 22 187 0 ENST00000376007.4:c.544G>A p.Ala182Thr p.A182T ENST00000376007 NM_080686.2 182 Gct/Act 0 +PRRC2C UCSF GRCh37 1 171535927 171535927 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 12 142 0 ENST00000338920.4:c.6497C>T p.Thr2166Ile p.T2166I ENST00000338920 NM_015172.3 2166 aCt/aTt 0 +PRRC2C UCSF GRCh37 1 171509943 171509943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 44 289 0 ENST00000338920.4:c.3332G>A p.Ser1111Asn p.S1111N ENST00000338920 NM_015172.3 1111 aGt/aAt 0 +PRRT3 UCSF GRCh37 3 9987933 9987933 + missense_variant,NMD_transcript_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 23 151 0 ENST00000295984.3:c.2924C>T p.Ser975Phe p.S975F ENST00000295984 975 tCc/tTc 0 +PRRX1 UCSF GRCh37 1 170695366 170695366 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 29 190 0 ENST00000239461.6:c.423G>A p.Trp141Ter p.W141* ENST00000239461 NM_022716.2 141 tgG/tgA 0 +PRSS27 UCSF GRCh37 16 2764279 2764279 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 22 202 0 ENST00000302641.3:c.295G>A p.Gly99Arg p.G99R ENST00000302641 NM_031948.3 99 Gga/Aga 0 +PRSS36 UCSF GRCh37 16 31155070 31155070 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 161 19 200 0 ENST00000268281.4:c.809G>A p.Arg270Lys p.R270K ENST00000268281 NM_173502.4 270 aGa/aAa 0 +PRSS57 UCSF GRCh37 19 691942 691942 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 16 58 0 ENST00000329267.7:c.297C>T p.Thr99= p.T99= ENST00000329267 NM_214710.3 99 acC/acT 0 +PRUNE2 UCSF GRCh37 9 79323744 79323744 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 429 65 600 0 ENST00000376718.3:c.3446G>A p.Ser1149Asn p.S1149N ENST00000376718 NM_015225.2 1149 aGt/aAt 0 +PRUNE2 UCSF GRCh37 9 79320935 79320935 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 46 336 0 ENST00000376718.3:c.6255G>A p.Glu2085= p.E2085= ENST00000376718 NM_015225.2 2085 gaG/gaA 0 +PRX UCSF GRCh37 19 40899917 40899917 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 4 31 0 ENST00000324001.7:c.4342C>T p.Pro1448Ser p.P1448S ENST00000324001 NM_181882.2 1448 Cca/Tca 0 +PSD UCSF GRCh37 10 104172277 104172277 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 18 176 0 ENST00000020673.5:c.1609G>A p.Glu537Lys p.E537K ENST00000020673 NM_001270966.1 537 Gag/Aag 0 +PSD2 UCSF GRCh37 5 139189372 139189372 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 22 84 0 ENST00000274710.3:c.347C>T p.Pro116Leu p.P116L ENST00000274710 NM_032289.2 116 cCa/cTa 0 +PSEN2 UCSF GRCh37 1 227083262 227083262 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 42 210 0 ENST00000366783.3:c.1329C>T p.Ser443= p.S443= ENST00000366783 NM_000447.2 443 tcC/tcT 0 +PSMB5 UCSF GRCh37 14 23502717 23502717 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 35 315 0 ENST00000361611.6:c.365G>A p.Cys122Tyr p.C122Y ENST00000361611 NM_002797.3 122 tGt/tAt 0 +PSMB6 UCSF GRCh37 17 4700831 4700831 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 36 250 1 ENST00000270586.3:c.269C>T p.Ala90Val p.A90V ENST00000270586 NM_002798.2 90 gCt/gTt 0 +PSMD3 UCSF GRCh37 17 38146367 38146367 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 7 23 0 ENST00000264639.4:c.898C>T p.Leu300= p.L300= ENST00000264639 NM_002809.3 300 Ctg/Ttg 0 +PSPC1 UCSF GRCh37 13 20325505 20325505 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 19 97 0 ENST00000338910.4:c.873G>A p.Glu291= p.E291= ENST00000338910 NM_001042414.2 291 gaG/gaA 0 +PSTPIP1 UCSF GRCh37 15 77328155 77328155 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 17 84 0 ENST00000558012.1:c.998C>T p.Thr333Ile p.T333I ENST00000558012 NM_003978.3 333 aCc/aTc 0 +PTAR1 UCSF GRCh37 9 72374784 72374784 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 15 119 0 ENST00000340434.4:c.71G>A p.Arg24Lys p.R24K ENST00000340434 NM_001099666.1 24 aGg/aAg 0 +PTBP2 UCSF GRCh37 1 97217025 97217025 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 10 110 0 ENST00000426398.2:c.84G>A p.Pro28= p.P28= ENST00000426398 NM_021190.2 28 ccG/ccA 0 +PTCH1 UCSF GRCh37 9 98222034 98222034 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 15 90 0 ENST00000331920.6:c.2735G>A p.Gly912Asp p.G912D ENST00000331920 NM_000264.3 912 gGc/gAc 0 +PTEN UCSF GRCh37 10 89692877 89692877 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 146 49 394 0 ENST00000371953.3:c.361G>A p.Ala121Thr p.A121T ENST00000371953 NM_000314.4 121 Gca/Aca 0 +PTEN UCSF GRCh37 10 89711875 89711875 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 49 15 134 0 ENST00000371953.3:c.493G>A p.Gly165Arg p.G165R ENST00000371953 NM_000314.4 165 Gga/Aga 0 +PTGDR UCSF GRCh37 14 52735256 52735256 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 211 45 319 0 ENST00000306051.2:c.724G>A p.Asp242Asn p.D242N ENST00000306051 NM_000953.2 242 Gac/Aac 0 +PTK2B UCSF GRCh37 8 27287616 27287616 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 617 78 603 0 ENST00000346049.5:c.558C>T p.Phe186= p.F186= ENST00000346049 NM_173176.2 186 ttC/ttT 0 +PTPDC1 UCSF GRCh37 9 96860280 96860280 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 25 296 0 ENST00000375360.3:c.1270C>T p.Pro424Ser p.P424S ENST00000375360 NM_001253830.1 424 Ccc/Tcc 0 +PTPN14 UCSF GRCh37 1 214557450 214557450 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 25 128 0 ENST00000366956.5:c.1748C>T p.Ala583Val p.A583V ENST00000366956 NM_005401.4 583 gCc/gTc 0 +PTPN21 UCSF GRCh37 14 88946277 88946277 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.000,1000g2011may_all_0.0020 P24_Rec2 Untested WXS Illumina HiSeq 67 14 71 0 ENST00000328736.3:c.1498G>A p.Ala500Thr p.A500T ENST00000328736 500 Gca/Aca 0 +PTPN23 UCSF GRCh37 3 47451032 47451032 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 12 92 0 ENST00000265562.4:c.1923G>A p.Arg641= p.R641= ENST00000265562 NM_015466.2 641 cgG/cgA 0 +PTPRD UCSF GRCh37 9 8485797 8485797 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 10 87 0 ENST00000356435.5:c.3020C>T p.Pro1007Leu p.P1007L ENST00000356435 1007 cCc/cTc 0 +PTPRH UCSF GRCh37 19 55693383 55693383 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 337 61 511 0 ENST00000376350.3:c.3198+1G>A p.X1066_splice ENST00000376350 NM_002842.3 0 +PTPRH UCSF GRCh37 19 55715304 55715304 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 37 262 0 ENST00000376350.3:c.732G>A p.Gln244= p.Q244= ENST00000376350 NM_002842.3 244 caG/caA 0 +PTPRM UCSF GRCh37 18 8069855 8069855 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 24 186 0 ENST00000332175.8:c.1304G>A p.Trp435Ter p.W435* ENST00000332175 NM_002845.3 435 tGg/tAg 0 +PUM1 UCSF GRCh37 1 31425201 31425201 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 5 58 0 ENST00000257075.5:c.2601G>A p.Gln867= p.Q867= ENST00000257075 NM_014676.2 867 caG/caA 0 +PUS7 UCSF GRCh37 7 105148954 105148954 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 67 203 0 ENST00000356362.2:c.6G>A p.Glu2= p.E2= ENST00000356362 NM_019042.3 2 gaG/gaA 0 +PUS7 UCSF GRCh37 7 105105815 105105815 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 59 226 0 ENST00000356362.2:c.1572C>T p.Ile524= p.I524= ENST00000356362 NM_019042.3 524 atC/atT 0 +PUSL1 UCSF GRCh37 1 1244534 1244534 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 19 144 0 ENST00000379031.5:c.204G>A p.Gly68= p.G68= ENST00000379031 NM_153339.1 68 ggG/ggA 0 +PVRL4 UCSF GRCh37 1 161042643 161042643 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 171 24 225 0 ENST00000368012.3:c.1341G>A p.Thr447= p.T447= ENST00000368012 NM_030916.2 447 acG/acA 0 +PXN UCSF GRCh37 12 120661972 120661972 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 15 114 0 ENST00000228307.7:c.222C>T p.Ser74= p.S74= ENST00000228307 NM_001080855.2 74 tcC/tcT 0 +PYCARD UCSF GRCh37 16 31212947 31212947 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 12 86 0 ENST00000247470.9:c.547G>A p.Glu183Lys p.E183K ENST00000247470 NM_013258.4 183 Gag/Aag 0 +QRICH1 UCSF GRCh37 3 49095184 49095184 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 30 213 0 ENST00000357496.2:c.449C>T p.Ser150Phe p.S150F ENST00000357496 NM_017730.2 150 tCc/tTc 0 +RAB11B UCSF GRCh37 19 8467013 8467013 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 9 74 0 ENST00000328024.6:c.280G>A p.Ala94Thr p.A94T ENST00000328024 NM_004218.3 94 Gcc/Acc 0 +RAB25 UCSF GRCh37 1 156040048 156040048 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 263 49 341 0 ENST00000361084.5:c.612G>A p.Gly204= p.G204= ENST00000361084 NM_020387.2 204 ggG/ggA 0 +RAB33B UCSF GRCh37 4 140394125 140394125 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 9 216 0 ENST00000305626.5:c.535G>A p.Ala179Thr p.A179T ENST00000305626 NM_031296.1 179 Gct/Act 0 +RAB39 UCSF GRCh37 11 107832857 107832857 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 30 256 0 ENST00000320578.2:c.413C>T p.Thr138Ile p.T138I ENST00000320578 NM_017516.1 138 aCa/aTa 0 +RAB41 UCSF GRCh37 X 69502395 69502395 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 62 108 0 ENST00000374473.2:c.137C>T p.Ser46Phe p.S46F ENST00000374473 46 tCc/tTc 0 +RAB6A UCSF GRCh37 11 73441816 73441816 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 11 42 0 ENST00000336083.3:c.123C>T p.Thr41= p.T41= ENST00000336083 NM_198896.1 41 acC/acT 0 +RAB7A UCSF GRCh37 3 128514235 128514235 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 23 161 0 ENST00000265062.3:c.25C>T p.Leu9= p.L9= ENST00000265062 NM_004637.5 9 Ctg/Ttg 0 +RAB8A UCSF GRCh37 19 16229055 16229055 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 12 107 0 ENST00000300935.3:c.144G>A p.Arg48= p.R48= ENST00000300935 NM_005370.4 48 agG/agA 0 +RAB9B UCSF GRCh37 X 103080138 103080138 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 29 129 0 ENST00000243298.2:c.577G>A p.Gly193Ser p.G193S ENST00000243298 NM_016370.2 193 Ggc/Agc 0 +RAB9B UCSF GRCh37 X 103080687 103080687 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 14 195 0 ENST00000243298.2:c.28G>A p.Val10Ile p.V10I ENST00000243298 NM_016370.2 10 Gtc/Atc 0 +RABEP1 UCSF GRCh37 17 5253909 5253909 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 21 257 0 ENST00000537505.1:c.819G>A p.Leu273= p.L273= ENST00000537505 273 ctG/ctA 0 +RAD52 UCSF GRCh37 12 1042140 1042140 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 333 47 381 0 ENST00000358495.3:c.84+1G>A p.X28_splice ENST00000358495 NM_134424.2 0 +RADIL UCSF GRCh37 7 4841284 4841284 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 23 0 ENST00000399583.3:c.2842G>A p.Gly948Arg p.G948R ENST00000399583 NM_018059.4 948 Gga/Aga 0 +RAET1G UCSF GRCh37 6 150239357 150239357 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 16 87 0 ENST00000367360.2:c.795C>T p.Pro265= p.P265= ENST00000367360 NM_001001788.2 265 ccC/ccT 0 +RAG1 UCSF GRCh37 11 36596534 36596534 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 12 108 0 ENST00000299440.5:c.1680C>T p.Phe560= p.F560= ENST00000299440 NM_000448.2 560 ttC/ttT 0 +RAI14 UCSF GRCh37 5 34823332 34823332 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 28 260 0 ENST00000265109.3:c.1385G>A p.Arg462Gln p.R462Q ENST00000265109 NM_015577.2 462 cGa/cAa 0 +RALGAPA2 UCSF GRCh37 20 20506958 20506958 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 15 149 0 ENST00000202677.7:c.3631C>T p.Leu1211= p.L1211= ENST00000202677 NM_020343.3 1211 Ctg/Ttg 0 +RAPGEF5 UCSF GRCh37 7 22186635 22186635 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 428 54 456 0 ENST00000401957.2:c.978C>T p.Asn326= p.N326= ENST00000401957 326 aaC/aaT 0 +RARS UCSF GRCh37 5 167944905 167944905 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 19 229 0 ENST00000231572.3:c.1711G>A p.Glu571Lys p.E571K ENST00000231572 NM_002887.3 571 Gaa/Aaa 0 +RASAL3 UCSF GRCh37 19 15564017 15564017 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 14 104 0 ENST00000343625.7:c.2571C>T p.Ser857= p.S857= ENST00000343625 NM_022904.1 857 tcC/tcT 0 +RASGRF1 UCSF GRCh37 15 79307703 79307703 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 13 160 0 ENST00000419573.3:c.1792G>A p.Glu598Lys p.E598K ENST00000419573 NM_002891.4 598 Gaa/Aaa 0 +RASGRF2 UCSF GRCh37 5 80366380 80366380 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 13 129 0 ENST00000265080.4:c.613G>A p.Asp205Asn p.D205N ENST00000265080 NM_006909.2 205 Gac/Aac 0 +RASGRF2 UCSF GRCh37 5 80497218 80497218 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 12 169 0 ENST00000265080.4:c.2863G>A p.Asp955Asn p.D955N ENST00000265080 NM_006909.2 955 Gac/Aac 0 +RASGRP3 UCSF GRCh37 2 33774715 33774715 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 233 26 333 0 ENST00000402538.3:c.1439G>A p.Arg480Lys p.R480K ENST00000402538 NM_170672.2 480 aGa/aAa 0 +RASGRP4 UCSF GRCh37 19 38900712 38900712 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 17 118 0 ENST00000587738.1:c.1990C>T p.Pro664Ser p.P664S ENST00000587738 664 Cca/Tca 0 +RASSF2 UCSF GRCh37 20 4771121 4771121 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 14 148 0 ENST00000379376.2:c.513C>T p.Ile171= p.I171= ENST00000379376 NM_170774.1 171 atC/atT 0 +RB1CC1 UCSF GRCh37 8 53574101 53574101 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 10 68 0 ENST00000025008.5:c.1352G>A p.Arg451Lys p.R451K ENST00000025008 NM_014781.4 451 aGa/aAa 0 +RBBP7 UCSF GRCh37 X 16887659 16887659 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 61 86 0 ENST00000380087.2:c.17-316G>A *6* ENST00000380087 0 +RBFOX1 UCSF GRCh37 16 7726800 7726800 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 31 227 0 ENST00000547338.1:c.955G>A p.Ala319Thr p.A319T ENST00000547338 NM_001142334.1 319 Gcc/Acc 0 +RBFOX2 UCSF GRCh37 22 36142030 36142030 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 8 82 0 ENST00000438146.2:c.1251G>A p.Val417= p.V417= ENST00000438146 NM_001082578.1 417 gtG/gtA 0 +RBL1 UCSF GRCh37 20 35635934 35635934 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 17 139 0 ENST00000373664.3:c.2751C>T p.Asp917= p.D917= ENST00000373664 NM_002895.3 917 gaC/gaT 0 +RBM12 UCSF GRCh37 20 34241786 34241786 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 339 82 588 0 ENST00000359646.1:c.1459G>A p.Ala487Thr p.A487T ENST00000359646 487 Gct/Act 0 +RBM14 UCSF GRCh37 11 66393129 66393129 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 13 22 0 ENST00000310137.4:c.1782G>A p.Lys594= p.K594= ENST00000310137 NM_006328.3 594 aaG/aaA 0 +RBM15 UCSF GRCh37 1 110882844 110882844 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 25 175 0 ENST00000369784.3:c.817G>A p.Val273Ile p.V273I ENST00000369784 NM_022768.4 273 Gtc/Atc 0 +RBM15 UCSF GRCh37 1 110888949 110888949 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 11 114 0 ENST00000369784.3:c.*60G>A *20* ENST00000369784 NM_022768.4 0 +RBM15B UCSF GRCh37 3 51431474 51431474 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 20 233 0 ENST00000323686.4:c.2644G>A p.Val882Met p.V882M ENST00000323686 NM_013286.4 882 Gtg/Atg 0 +RBM19 UCSF GRCh37 12 114282513 114282513 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 32 0 ENST00000261741.5:c.2745C>T p.Thr915= p.T915= ENST00000261741 NM_016196.3 915 acC/acT 0 +RBM20 UCSF GRCh37 10 112570210 112570210 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 12 65 0 ENST00000369519.3:c.1870G>A p.Glu624Lys p.E624K ENST00000369519 NM_001134363.1 624 Gaa/Aaa 0 +RBM45 UCSF GRCh37 2 178981094 178981094 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 22 233 0 ENST00000286070.5:c.406C>T p.Leu136= p.L136= ENST00000286070 NM_152945.2 136 Ctg/Ttg 0 +RBM47 UCSF GRCh37 4 40438596 40438596 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 448 66 693 0 ENST00000295971.7:c.1192C>T p.Leu398Phe p.L398F ENST00000295971 NM_001098634.1 398 Ctc/Ttc 0 +RBMS3 UCSF GRCh37 3 29323205 29323205 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 11 91 0 ENST00000383767.2:c.33C>T p.Tyr11= p.Y11= ENST00000383767 11 taC/taT 0 +RBPJ UCSF GRCh37 4 26431661 26431661 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 33 137 0 ENST00000342295.1:c.1069G>A p.Val357Ile p.V357I ENST00000342295 NM_005349.3 357 Gta/Ata 0 +RBPJL UCSF GRCh37 20 43943147 43943147 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 4 32 0 ENST00000343694.3:c.962C>T p.Pro321Leu p.P321L ENST00000343694 NM_001281449.1 321 cCc/cTc 0 +RC3H1 UCSF GRCh37 1 173916628 173916628 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 26 161 0 ENST00000258349.4:c.2616C>T p.Asp872= p.D872= ENST00000258349 NM_172071.2 872 gaC/gaT 0 +RDBP UCSF GRCh37 6 31922509 31922509 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 479 86 601 0 ENST00000375429.3:c.565G>A p.Asp189Asn p.D189N ENST00000375429 NM_002904.5 189 Gac/Aac 0 +RDBP UCSF GRCh37 6 31922869 31922869 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 43 338 0 ENST00000375429.3:c.371C>T p.Ser124Phe p.S124F ENST00000375429 NM_002904.5 124 tCc/tTc 0 +RDX UCSF GRCh37 11 110150413 110150413 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 12 101 0 ENST00000343115.4:c.5C>T p.Pro2Leu p.P2L ENST00000343115 NM_001260494.1 2 cCg/cTg 0 +RELN UCSF GRCh37 7 103230049 103230049 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 29 176 0 ENST00000428762.1:c.4139C>T p.Ala1380Val p.A1380V ENST00000428762 NM_005045.3 1380 gCa/gTa 0 +REPIN1 UCSF GRCh37 7 150068904 150068904 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 224 26 186 0 ENST00000397281.2:c.574C>T p.Leu192= p.L192= ENST00000397281 NM_013400.3 192 Cta/Tta 0 +RERE UCSF GRCh37 1 8422742 8422742 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 27 349 0 ENST00000337907.3:c.1902+1G>A p.X634_splice ENST00000337907 NM_012102.3 0 +RET UCSF GRCh37 10 43608383 43608383 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 76 0 ENST00000355710.3:c.1731C>T p.Asp577= p.D577= ENST00000355710 NM_020975.4 577 gaC/gaT 0 +RET UCSF GRCh37 10 43610025 43610025 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 426 63 627 0 ENST00000355710.3:c.1977C>T p.Cys659= p.C659= ENST00000355710 NM_020975.4 659 tgC/tgT 0 +REV3L UCSF GRCh37 6 111737541 111737541 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 16 199 0 ENST00000358835.3:c.274G>A p.Gly92Ser p.G92S ENST00000358835 92 Ggc/Agc 0 +RFC4 UCSF GRCh37 3 186512468 186512468 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 16 131 0 ENST00000296273.2:c.389C>T p.Thr130Ile p.T130I ENST00000296273 NM_002916.3 130 aCt/aTt 0 +RFNG UCSF GRCh37 17 80009379 80009379 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 3 29 0 ENST00000310496.4:c.264G>A p.Gln88= p.Q88= ENST00000310496 NM_002917.1 88 caG/caA 0 +RFTN2 UCSF GRCh37 2 198436747 198436747 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 542 78 743 0 ENST00000295049.4:c.1491G>A p.Gln497= p.Q497= ENST00000295049 NM_144629.2 497 caG/caA 0 +RFX6 UCSF GRCh37 6 117199071 117199071 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 7 72 0 ENST00000332958.2:c.336G>A p.Gln112= p.Q112= ENST00000332958 NM_173560.3 112 caG/caA 0 +RFX7 UCSF GRCh37 15 56435004 56435004 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 16 140 0 ENST00000559447.2:c.82C>T p.Pro28Ser p.P28S ENST00000559447 28 Ccc/Tcc 0 +RGS18 UCSF GRCh37 1 192153595 192153595 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 81 324 0 ENST00000367460.3:c.619C>T p.Gln207Ter p.Q207* ENST00000367460 NM_130782.2 207 Cag/Tag 0 +RHAG UCSF GRCh37 6 49587023 49587023 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 3 33 0 ENST00000371175.4:c.210C>T p.Thr70= p.T70= ENST00000371175 NM_000324.2 70 acC/acT 0 +RHOT2 UCSF GRCh37 16 718393 718393 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 71 203 0 ENST00000315082.4:c.78C>T p.Gly26= p.G26= ENST00000315082 NM_138769.2 26 ggC/ggT 0 +RHOXF1 UCSF GRCh37 X 119249374 119249374 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 13 83 0 ENST00000217999.2:c.398+1G>A p.X133_splice ENST00000217999 NM_139282.2 0 +RHPN1 UCSF GRCh37 8 144460959 144460959 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 139 356 0 ENST00000289013.6:c.553C>T p.Pro185Ser p.P185S ENST00000289013 NM_052924.2 185 Cct/Tct 0 +RICTOR UCSF GRCh37 5 38957753 38957753 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 35 322 0 ENST00000357387.3:c.2499+1G>A p.X833_splice ENST00000357387 NM_152756.3 0 +RICTOR UCSF GRCh37 5 38952427 38952427 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 281 41 397 0 ENST00000357387.3:c.2998C>T p.Leu1000= p.L1000= ENST00000357387 NM_152756.3 1000 Ctg/Ttg 0 +RIMBP2 UCSF GRCh37 12 130963546 130963546 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 7 64 0 ENST00000261655.4:c.13G>A p.Ala5Thr p.A5T ENST00000261655 NM_015347.4 5 Gct/Act 0 +RLF UCSF GRCh37 1 40661304 40661304 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 14 67 0 ENST00000372771.4:c.475G>A p.Glu159Lys p.E159K ENST00000372771 NM_012421.3 159 Gag/Aag 0 +RMI1 UCSF GRCh37 9 86617385 86617385 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 293 55 430 1 ENST00000325875.3:c.1484C>T p.Ser495Phe p.S495F ENST00000325875 NM_024945.2 495 tCt/tTt 0 +RND1 UCSF GRCh37 12 49254849 49254849 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 10 72 0 ENST00000309739.5:c.384C>T p.Asp128= p.D128= ENST00000309739 NM_014470.3 128 gaC/gaT 0 +RNF126 UCSF GRCh37 19 650255 650255 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 13 25 0 ENST00000292363.5:c.485C>T p.Thr162Ile p.T162I ENST00000292363 NM_194460.2 162 aCc/aTc 0 +RNF144A UCSF GRCh37 2 7164616 7164616 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 23 192 0 ENST00000320892.6:c.626C>T p.Ala209Val p.A209V ENST00000320892 NM_014746.3 209 gCc/gTc 0 +RNF146 UCSF GRCh37 6 127608726 127608726 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 36 268 0 ENST00000368314.1:c.968C>T p.Pro323Leu p.P323L ENST00000368314 NM_001242850.1 323 cCc/cTc 0 +RNF17 UCSF GRCh37 13 25418078 25418078 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 16 259 0 ENST00000255324.5:c.2800C>T p.Gln934Ter p.Q934* ENST00000255324 NM_031277.2 934 Cag/Tag 0 +RNF182 UCSF GRCh37 6 13977943 13977943 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 72 256 0 ENST00000488300.1:c.593C>T p.Pro198Leu p.P198L ENST00000488300 NM_152737.3 198 cCc/cTc 0 +RNF2 UCSF GRCh37 1 185067214 185067214 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 10 86 0 ENST00000367510.3:c.475G>A p.Gly159Ser p.G159S ENST00000367510 NM_007212.3 159 Ggc/Agc 0 +RNF213 UCSF GRCh37 17 78343302 78343302 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 6 64 0 ENST00000582970.1:c.12156G>A p.Arg4052= p.R4052= ENST00000582970 NM_001256071.1 4052 agG/agA 0 +RNF34 UCSF GRCh37 12 121858387 121858387 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 11 67 0 ENST00000361234.5:c.734G>A p.Gly245Glu p.G245E ENST00000361234 NM_025126.3 245 gGg/gAg 0 +RNF44 UCSF GRCh37 5 175958506 175958506 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 45 0 ENST00000274811.4:c.423G>A p.Met141Ile p.M141I ENST00000274811 NM_014901.4 141 atG/atA 0 +RNH1 UCSF GRCh37 11 498538 498538 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 21 161 0 ENST00000354420.2:c.875C>T p.Ala292Val p.A292V ENST00000354420 NM_203387.2 292 gCc/gTc 0 +RORA UCSF GRCh37 15 61521328 61521328 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 11 96 0 ENST00000335670.6:c.90G>A p.Pro30= p.P30= ENST00000335670 NM_134261.2 30 ccG/ccA 0 +RPAP1 UCSF GRCh37 15 41816446 41816446 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 7 61 0 ENST00000304330.4:c.2082C>T p.Leu694= p.L694= ENST00000304330 NM_015540.2 694 ctC/ctT 0 +RPL5 UCSF GRCh37 1 93299127 93299127 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 16 99 0 ENST00000370321.3:c.99G>A p.Arg33= p.R33= ENST00000370321 NM_000969.3 33 cgG/cgA 0 +RPL7 UCSF GRCh37 8 74204015 74204015 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 25 235 0 ENST00000352983.2:c.421G>A p.Ala141Thr p.A141T ENST00000352983 141 Gca/Aca 0 +RPP25 UCSF GRCh37 15 75248864 75248864 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 72 184 0 ENST00000322177.5:c.61G>A p.Gly21Ser p.G21S ENST00000322177 NM_017793.2 21 Ggc/Agc 0 +RPRD2 UCSF GRCh37 1 150443190 150443190 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 19 256 0 ENST00000369068.4:c.1766G>A p.Ser589Asn p.S589N ENST00000369068 NM_015203.3 589 aGc/aAc 0 +RPS23 UCSF GRCh37 5 81573621 81573621 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 242 45 335 0 ENST00000296674.8:c.55G>A p.Asp19Asn p.D19N ENST00000296674 NM_001025.4 19 Gac/Aac 0 +RPS6KA2 UCSF GRCh37 6 167275595 167275595 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 7 97 0 ENST00000503859.1:c.63+1G>A p.X21_splice ENST00000503859 NM_001006932.1 0 +RPS6KA4 UCSF GRCh37 11 64135622 64135622 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 30 293 0 ENST00000334205.4:c.1090C>T p.Pro364Ser p.P364S ENST00000334205 NM_003942.2 364 Ccc/Tcc 0 +RPS6KA5 UCSF GRCh37 14 91389456 91389456 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 24 274 0 ENST00000261991.3:c.702+1G>A p.X234_splice ENST00000261991 NM_004755.2 0 +RPS6KL1 UCSF GRCh37 14 75374226 75374226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 26 198 0 ENST00000354625.2:c.1358C>T p.Ser453Phe p.S453F ENST00000354625 453 tCc/tTc 0 +RPTN UCSF GRCh37 1 152127274 152127274 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 762 127 903 0 ENST00000316073.3:c.2301C>T p.Asn767= p.N767= ENST00000316073 NM_001122965.1 767 aaC/aaT 0 +RPTOR UCSF GRCh37 17 78765296 78765296 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 10 123 0 ENST00000306801.3:c.877G>A p.Asp293Asn p.D293N ENST00000306801 NM_020761.2 293 Gat/Aat 0 +RPUSD2 UCSF GRCh37 15 40861556 40861556 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 10 77 0 ENST00000315616.7:c.20G>A p.Gly7Glu p.G7E ENST00000315616 NM_152260.1 7 gGa/gAa 0 +RRAGA UCSF GRCh37 9 19049980 19049980 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 22 230 0 ENST00000380527.1:c.323C>T p.Ser108Leu p.S108L ENST00000380527 NM_006570.4 108 tCg/tTg 0 +RREB1 UCSF GRCh37 6 7231216 7231216 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 17 137 0 ENST00000349384.6:c.2884G>A p.Glu962Lys p.E962K ENST00000349384 NM_001003698.3 962 Gag/Aag 0 +RREB1 UCSF GRCh37 6 7231282 7231282 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 14 104 0 ENST00000349384.6:c.2950G>A p.Gly984Arg p.G984R ENST00000349384 NM_001003698.3 984 Ggg/Agg 0 +RRN3 UCSF GRCh37 16 15166849 15166849 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 10 118 0 ENST00000198767.6:c.1086C>T p.Cys362= p.C362= ENST00000198767 NM_018427.3 362 tgC/tgT 0 +RRP1 UCSF GRCh37 21 45217919 45217919 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 7 43 0 ENST00000497547.1:c.749C>T p.Ser250Phe p.S250F ENST00000497547 NM_003683.5 250 tCc/tTc 0 +RRP9 UCSF GRCh37 3 51968521 51968521 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 21 153 0 ENST00000232888.6:c.1227C>T p.Phe409= p.F409= ENST00000232888 NM_004704.4 409 ttC/ttT 0 +RSAD1 UCSF GRCh37 17 48557042 48557042 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 9 67 0 ENST00000258955.2:c.188C>T p.Pro63Leu p.P63L ENST00000258955 NM_018346.1 63 cCt/cTt 0 +RSF1 UCSF GRCh37 11 77394779 77394779 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 43 373 0 ENST00000308488.6:c.3041G>A p.Arg1014Lys p.R1014K ENST00000308488 1014 aGa/aAa 0 +RSPH4A UCSF GRCh37 6 116937853 116937853 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 43 135 0 ENST00000229554.5:c.67C>T p.Pro23Ser p.P23S ENST00000229554 NM_001010892.2 23 Cca/Tca 0 +RSPH6A UCSF GRCh37 19 46305384 46305384 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 258 38 398 0 ENST00000221538.3:c.1792G>A p.Asp598Asn p.D598N ENST00000221538 NM_030785.3 598 Gat/Aat 0 +RTCD1 UCSF GRCh37 1 100732140 100732140 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 17 143 0 ENST00000370128.4:c.106G>A p.Val36Met p.V36M ENST00000370128 NM_003729.3 36 Gtg/Atg 0 +RTEL1 UCSF GRCh37 20 62292650 62292650 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 5 30 0 ENST00000370018.3:c.103-1G>A p.X35_splice ENST00000370018 NM_032957.4 0 +RTTN UCSF GRCh37 18 67857947 67857947 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 11 173 0 ENST00000255674.6:c.1016G>A p.Ser339Asn p.S339N ENST00000255674 NM_173630.3 339 aGt/aAt 0 +RUNDC1 UCSF GRCh37 17 41143722 41143722 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 28 290 0 ENST00000361677.1:c.1831G>A p.Asp611Asn p.D611N ENST00000361677 NM_173079.2 611 Gat/Aat 0 +RUNDC3A UCSF GRCh37 17 42386308 42386308 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 6 52 0 ENST00000426726.3:c.107+1G>A p.X36_splice ENST00000426726 NM_001144825.1 0 +RUSC2 UCSF GRCh37 9 35555506 35555506 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 55 165 0 ENST00000361226.3:c.2464C>T p.Pro822Ser p.P822S ENST00000361226 NM_014806.2 822 Cct/Tct 0 +RXFP1 UCSF GRCh37 4 159554622 159554622 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 8 160 0 ENST00000307765.5:c.965C>T p.Ser322Leu p.S322L ENST00000307765 NM_001253728.1 322 tCa/tTa 0 +RXRA UCSF GRCh37 9 137320968 137320968 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 33 284 0 ENST00000481739.1:c.925C>T p.Leu309Phe p.L309F ENST00000481739 NM_002957.4 309 Ctc/Ttc 0 +RXRA UCSF GRCh37 9 137321053 137321053 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 60 159 0 ENST00000481739.1:c.1010C>T p.Ala337Val p.A337V ENST00000481739 NM_002957.4 337 gCc/gTc 0 +RYBP UCSF GRCh37 3 72427537 72427537 + stop_retained_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 16 211 0 ENST00000477973.2:c.951G>A p.Ter318= p.*318= ENST00000477973 NM_012234.5 318 tGa/tAa 0 +RYR1 UCSF GRCh37 19 38931413 38931413 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 47 0 ENST00000359596.3:c.74C>T p.Ala25Val p.A25V ENST00000359596 25 gCt/gTt 0 +RYR1 UCSF GRCh37 19 38985127 38985127 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 14 91 0 ENST00000359596.3:c.6410C>T p.Ala2137Val p.A2137V ENST00000359596 2137 gCc/gTc 0 +RYR1 UCSF GRCh37 19 38993213 38993213 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 48 333 0 ENST00000359596.3:c.7681C>T p.Leu2561Phe p.L2561F ENST00000359596 2561 Ctc/Ttc 0 +RYR1 UCSF GRCh37 19 38985070 38985070 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 7 39 0 ENST00000359596.3:c.6353G>A p.Arg2118Gln p.R2118Q ENST00000359596 2118 cGg/cAg 0 +RYR1 UCSF GRCh37 19 38964070 38964070 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 10 111 0 ENST00000359596.3:c.3819C>T p.His1273= p.H1273= ENST00000359596 1273 caC/caT 0 +RYR3 UCSF GRCh37 15 34040384 34040384 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 3 58 0 ENST00000389232.4:c.8059G>A p.Glu2687Lys p.E2687K ENST00000389232 NM_001036.3 2687 Gag/Aag 0 +S100PBP UCSF GRCh37 1 33292420 33292420 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 22 122 0 ENST00000373475.5:c.720G>A p.Arg240= p.R240= ENST00000373475 NM_022753.3 240 cgG/cgA 0 +S1PR1 UCSF GRCh37 1 101705160 101705160 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 446 51 564 0 ENST00000305352.6:c.620C>T p.Thr207Ile p.T207I ENST00000305352 NM_001400.4 207 aCc/aTc 0 +S1PR1 UCSF GRCh37 1 101705464 101705464 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 282 53 366 0 ENST00000305352.6:c.924C>T p.Pro308= p.P308= ENST00000305352 NM_001400.4 308 ccC/ccT 0 +SAG UCSF GRCh37 2 234237205 234237205 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 16 148 0 ENST00000409110.1:c.594G>A p.Trp198Ter p.W198* ENST00000409110 NM_000541.4 198 tgG/tgA 0 +SAMD15 UCSF GRCh37 14 77844770 77844770 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 15 154 0 ENST00000216471.4:c.1009C>T p.Pro337Ser p.P337S ENST00000216471 NM_001010860.1 337 Cct/Tct 0 +SAMD9 UCSF GRCh37 7 92730948 92730948 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 293 53 505 0 ENST00000379958.2:c.4463G>A p.Arg1488Lys p.R1488K ENST00000379958 NM_017654.3 1488 aGa/aAa 0 +SARDH UCSF GRCh37 9 136577769 136577769 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 10 77 0 ENST00000371872.4:c.1300G>A p.Glu434Lys p.E434K ENST00000371872 NM_007101.3 434 Gag/Aag 0 +SARDH UCSF GRCh37 9 136568071 136568071 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 9 54 0 ENST00000371872.4:c.1635G>A p.Glu545= p.E545= ENST00000371872 NM_007101.3 545 gaG/gaA 0 +SARM1 UCSF GRCh37 17 26715552 26715552 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 12 66 0 ENST00000457710.3:c.1815G>A p.Val605= p.V605= ENST00000457710 NM_015077.3 605 gtG/gtA 0 +SARS UCSF GRCh37 1 109779146 109779146 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 7 80 0 ENST00000234677.2:c.1233G>A p.Gly411= p.G411= ENST00000234677 NM_006513.3 411 ggG/ggA 0 +SART3 UCSF GRCh37 12 108931935 108931935 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 15 156 0 ENST00000228284.3:c.1107C>T p.Asn369= p.N369= ENST00000228284 NM_014706.3 369 aaC/aaT 0 +SBF2 UCSF GRCh37 11 9812175 9812175 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 16 155 0 ENST00000256190.8:c.4626G>A p.Trp1542Ter p.W1542* ENST00000256190 NM_030962.3 1542 tgG/tgA 0 +SCAF1 UCSF GRCh37 19 50154164 50154164 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 123 63 208 0 ENST00000360565.3:c.518G>A p.Arg173His p.R173H ENST00000360565 NM_021228.2 173 cGt/cAt 0 +SCAF1 UCSF GRCh37 19 50158012 50158012 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 239 34 370 0 ENST00000360565.3:c.3503G>A p.Gly1168Asp p.G1168D ENST00000360565 NM_021228.2 1168 gGc/gAc 0 +SCAF1 UCSF GRCh37 19 50157655 50157655 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 11 114 0 ENST00000360565.3:c.3366G>A p.Ala1122= p.A1122= ENST00000360565 NM_021228.2 1122 gcG/gcA 0 +SCAND3 UCSF GRCh37 6 28542726 28542726 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 16 213 0 ENST00000452236.2:c.1756C>T p.Pro586Ser p.P586S ENST00000452236 NM_052923.1 586 Cct/Tct 0 +SCIN UCSF GRCh37 7 12617790 12617790 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 12 105 0 ENST00000297029.5:c.301G>A p.Gly101Arg p.G101R ENST00000297029 NM_001112706.2 101 Gga/Aga 0 +SCN10A UCSF GRCh37 3 38783835 38783835 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 9 92 0 ENST00000449082.2:c.2053G>A p.Glu685Lys p.E685K ENST00000449082 NM_006514.2 685 Gag/Aag 0 +SCN1A UCSF GRCh37 2 166930062 166930062 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 32 270 0 ENST00000303395.4:c.70G>A p.Ala24Thr p.A24T ENST00000303395 24 Gct/Act 0 +SCN2A UCSF GRCh37 2 166152547 166152547 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 12 86 0 ENST00000283256.6:c.214G>A p.Glu72Lys p.E72K ENST00000283256 NM_021007.2 72 Gag/Aag 0 +SCN5A UCSF GRCh37 3 38592472 38592472 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 87 255 0 ENST00000333535.4:c.5391C>T p.Ile1797= p.I1797= ENST00000333535 1797 atC/atT 0 +SCNN1B UCSF GRCh37 16 23364211 23364211 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 252 35 376 0 ENST00000343070.2:c.401C>T p.Ala134Val p.A134V ENST00000343070 NM_000336.2 134 gCc/gTc 0 +SCNN1D UCSF GRCh37 1 1226800 1226800 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 26 71 0 ENST00000338555.2:c.1727G>A p.Ser576Asn p.S576N ENST00000338555 576 aGc/aAc 0 +SCNN1G UCSF GRCh37 16 23226446 23226446 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 36 109 0 ENST00000300061.2:c.1606G>A p.Gly536Ser p.G536S ENST00000300061 NM_001039.3 536 Ggc/Agc 0 +SCP2 UCSF GRCh37 1 53446172 53446172 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 27 254 0 ENST00000371514.3:c.930C>T p.Thr310= p.T310= ENST00000371514 NM_002979.4 310 acC/acT 0 +SCRN1 UCSF GRCh37 7 29983761 29983761 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 239 30 227 0 ENST00000242059.5:c.376G>A p.Ala126Thr p.A126T ENST00000242059 NM_001145515.1 126 Gcc/Acc 0 +SCYL1 UCSF GRCh37 11 65293787 65293787 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 4 19 0 ENST00000270176.5:c.568G>A p.Ala190Thr p.A190T ENST00000270176 NM_020680.3 190 Gct/Act 0 +SDCCAG3 UCSF GRCh37 9 139301920 139301920 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 4 33 0 ENST00000357365.3:c.496G>A p.Asp166Asn p.D166N ENST00000357365 NM_001039707.1 166 Gat/Aat 0 +SDF2L1 UCSF GRCh37 22 21997337 21997337 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 10 31 0 ENST00000248958.4:c.374C>T p.Ser125Phe p.S125F ENST00000248958 NM_022044.2 125 tCc/tTc 0 +SDK1 UCSF GRCh37 7 4249791 4249791 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 14 96 0 ENST00000404826.2:c.5536C>T p.Gln1846Ter p.Q1846* ENST00000404826 NM_152744.3 1846 Caa/Taa 0 +SEC14L1 UCSF GRCh37 17 75202374 75202374 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 4 22 0 ENST00000430767.4:c.1233G>A p.Val411= p.V411= ENST00000430767 NM_001204410.1 411 gtG/gtA 0 +SEC16B UCSF GRCh37 1 177901632 177901632 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 4 16 0 ENST00000308284.6:c.3005G>A p.Gly1002Glu p.G1002E ENST00000308284 NM_033127.2 1002 gGa/gAa 0 +SEC31B UCSF GRCh37 10 102266174 102266174 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 39 172 0 ENST00000370345.3:c.786G>A p.Gly262= p.G262= ENST00000370345 NM_015490.3 262 ggG/ggA 0 +SEC61A1 UCSF GRCh37 3 127785845 127785845 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 281 43 433 0 ENST00000243253.3:c.826T>C p.Tyr276His p.Y276H ENST00000243253 NM_013336.3 276 Tac/Cac 0 +SEC63 UCSF GRCh37 6 108243022 108243022 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 43 332 0 ENST00000369002.4:c.431G>A p.Arg144Lys p.R144K ENST00000369002 NM_007214.4 144 aGg/aAg 0 +SEC63 UCSF GRCh37 6 108215043 108215043 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 187 30 395 0 ENST00000369002.4:c.1499G>A p.Gly500Glu p.G500E ENST00000369002 NM_007214.4 500 gGg/gAg 0 +SECISBP2L UCSF GRCh37 15 49311736 49311736 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 8 79 0 ENST00000559471.1:c.1049G>A p.Cys350Tyr p.C350Y ENST00000559471 NM_001193489.1 350 tGc/tAc 0 +SEL1L UCSF GRCh37 14 81993227 81993227 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 35 261 0 ENST00000336735.4:c.190G>A p.Glu64Lys p.E64K ENST00000336735 NM_005065.5 64 Gaa/Aaa 0 +SEL1L2 UCSF GRCh37 20 13867010 13867010 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 16 192 0 ENST00000284951.5:c.824C>T p.Ser275Phe p.S275F ENST00000284951 275 tCt/tTt 0 +SELENBP1 UCSF GRCh37 1 151341631 151341631 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 8 38 0 ENST00000368868.5:c.209A>G p.Asp70Gly p.D70G ENST00000368868 NM_003944.3 70 gAc/gGc 0 +SELT UCSF GRCh37 3 150321233 150321233 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 71 0 ENST00000471696.1:c.84C>T p.Ser28= p.S28= ENST00000471696 NM_016275.3 28 agC/agT 0 +SEMA3E UCSF GRCh37 7 83036460 83036460 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 13 147 0 ENST00000307792.3:c.766G>A p.Glu256Lys p.E256K ENST00000307792 NM_012431.2 256 Gaa/Aaa 0 +SEMA3F UCSF GRCh37 3 50220407 50220407 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 18 150 0 ENST00000002829.3:c.974C>T p.Ser325Phe p.S325F ENST00000002829 NM_004186.3 325 tCt/tTt 0 +SEMA4C UCSF GRCh37 2 97530011 97530011 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 10 80 0 ENST00000305476.5:c.1071C>T p.Arg357= p.R357= ENST00000305476 NM_017789.4 357 cgC/cgT 0 +SEMA4D UCSF GRCh37 9 91994525 91994525 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 11 138 0 ENST00000356444.2:c.1683C>T p.Tyr561= p.Y561= ENST00000356444 561 taC/taT 0 +SEMA5B UCSF GRCh37 3 122631167 122631167 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 13 90 0 ENST00000357599.3:c.2748G>A p.Trp916Ter p.W916* ENST00000357599 NM_001256348.1 916 tgG/tgA 0 +SEMA6A UCSF GRCh37 5 115782924 115782924 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 20 192 0 ENST00000343348.6:c.2478G>A p.Gln826= p.Q826= ENST00000343348 NM_020796.3 826 caG/caA 0 +SENP7 UCSF GRCh37 3 101066866 101066866 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 45 189 0 ENST00000394095.2:c.1687G>A p.Asp563Asn p.D563N ENST00000394095 NM_020654.3 563 Gat/Aat 0 +SENP7 UCSF GRCh37 3 101049182 101049182 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 207 35 379 0 ENST00000394095.2:c.2747C>T p.Ser916Phe p.S916F ENST00000394095 NM_020654.3 916 tCc/tTc 0 +SEPT9 UCSF GRCh37 17 75488714 75488714 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 41 144 0 ENST00000427177.1:c.1392C>T p.Asp464= p.D464= ENST00000427177 NM_001113491.1 464 gaC/gaT 0 +SERPINA10 UCSF GRCh37 14 94752585 94752585 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 29 255 0 ENST00000261994.4:c.1003G>A p.Val335Ile p.V335I ENST00000261994 NM_001100607.2 335 Gtt/Att 0 +SERPINA11 UCSF GRCh37 14 94914700 94914700 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 15 183 0 ENST00000334708.3:c.412G>A p.Gly138Arg p.G138R ENST00000334708 NM_001080451.1 138 Gga/Aga 0 +SERPINA11 UCSF GRCh37 14 94914822 94914822 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 15 143 0 ENST00000334708.3:c.290C>T p.Ala97Val p.A97V ENST00000334708 NM_001080451.1 97 gCt/gTt 0 +SERPINF2 UCSF GRCh37 17 1649012 1649012 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 8 78 0 ENST00000324015.3:c.176G>A p.Gly59Asp p.G59D ENST00000324015 NM_000934.3 59 gGc/gAc 0 +SERTAD1 UCSF GRCh37 19 40929053 40929053 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 16 106 0 ENST00000357949.4:c.401C>T p.Pro134Leu p.P134L ENST00000357949 NM_013376.3 134 cCc/cTc 0 +SERTAD2 UCSF GRCh37 2 64863823 64863823 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 10 121 1 ENST00000313349.3:c.183G>A p.Lys61= p.K61= ENST00000313349 NM_014755.2 61 aaG/aaA 0 +SESN3 UCSF GRCh37 11 94910922 94910922 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 8 154 0 ENST00000536441.1:c.1208G>A p.Arg403Lys p.R403K ENST00000536441 NM_144665.3 403 aGa/aAa 0 +SETBP1 UCSF GRCh37 18 42530356 42530356 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 317 55 437 0 ENST00000282030.5:c.1051G>A p.Asp351Asn p.D351N ENST00000282030 NM_015559.2 351 Gac/Aac 0 +SETD8 UCSF GRCh37 12 123880969 123880969 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 14 110 0 ENST00000402868.3:c.587C>T p.Ala196Val p.A196V ENST00000402868 196 gCc/gTc 0 +SETDB2 UCSF GRCh37 13 50050655 50050655 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 7 109 0 ENST00000354234.4:c.349G>A p.Val117Ile p.V117I ENST00000354234 NM_001160308.1 117 Gta/Ata 0 +SETX UCSF GRCh37 9 135140211 135140211 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 22 206 0 ENST00000224140.5:c.7449G>A p.Gly2483= p.G2483= ENST00000224140 NM_015046.5 2483 ggG/ggA 0 +SEZ6L2 UCSF GRCh37 16 29899902 29899902 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 16 106 0 ENST00000308713.5:c.998G>A p.Gly333Asp p.G333D ENST00000308713 NM_001114099.2 333 gGc/gAc 0 +SF3A1 UCSF GRCh37 22 30749022 30749022 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 16 145 0 ENST00000215793.8:c.103C>T p.Pro35Ser p.P35S ENST00000215793 NM_005877.4 35 Cct/Tct 0 +SF3B2 UCSF GRCh37 11 65825560 65825560 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 5 57 0 ENST00000322535.6:c.813G>A p.Gln271= p.Q271= ENST00000322535 NM_006842.2 271 caG/caA 0 +SFI1 UCSF GRCh37 22 31946261 31946261 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 10 73 0 ENST00000400288.2:c.471G>A p.Met157Ile p.M157I ENST00000400288 NM_001007467.2 157 atG/atA 0 +SFI1 UCSF GRCh37 22 32000897 32000897 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 14 32 0 ENST00000400288.2:c.2020G>A p.Ala674Thr p.A674T ENST00000400288 NM_001007467.2 674 Gcc/Acc 0 +SFI1 UCSF GRCh37 22 31974436 31974436 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 7 51 0 ENST00000400288.2:c.1153C>T p.Leu385= p.L385= ENST00000400288 NM_001007467.2 385 Ctg/Ttg 0 +SFMBT1 UCSF GRCh37 3 52955848 52955848 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 16 143 0 ENST00000394752.3:c.1132-1G>A p.X378_splice ENST00000394752 NM_016329.3 0 +SFSWAP UCSF GRCh37 12 132195854 132195854 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 21 152 0 ENST00000261674.4:c.80G>A p.Gly27Asp p.G27D ENST00000261674 NM_004592.3 27 gGc/gAc 0 +SFTPB UCSF GRCh37 2 85895263 85895263 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 8 25 0 ENST00000393822.3:c.80C>T p.Pro27Leu p.P27L ENST00000393822 27 cCc/cTc 0 +SFTPB UCSF GRCh37 2 85894253 85894253 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 9 110 0 ENST00000393822.3:c.279G>A p.Lys93= p.K93= ENST00000393822 93 aaG/aaA 0 +SGCG UCSF GRCh37 13 23777883 23777883 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 11 116 0 ENST00000218867.3:c.50G>A p.Arg17Lys p.R17K ENST00000218867 NM_000231.2 17 aGg/aAg 0 +SGK223 UCSF GRCh37 8 8185591 8185591 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 20 107 0 ENST00000520004.1:c.2701G>A p.Gly901Ser p.G901S ENST00000520004 901 Ggc/Agc 0 +SGSM2 UCSF GRCh37 17 2275523 2275523 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 16 83 0 ENST00000426855.2:c.1482G>A p.Gln494= p.Q494= ENST00000426855 NM_001098509.1 494 caG/caA 0 +SGSM2 UCSF GRCh37 17 2276363 2276363 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 12 95 0 ENST00000426855.2:c.1770G>A p.Lys590= p.K590= ENST00000426855 NM_001098509.1 590 aaG/aaA 0 +SH2B1 UCSF GRCh37 16 28880534 28880534 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 84 248 0 ENST00000322610.8:c.1139G>A p.Cys380Tyr p.C380Y ENST00000322610 380 tGc/tAc 0 +SH2D1B UCSF GRCh37 1 162368778 162368778 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 24 198 0 ENST00000367929.2:c.298C>T p.Pro100Ser p.P100S ENST00000367929 NM_053282.4 100 Cca/Tca 0 +SH2D7 UCSF GRCh37 15 78393664 78393664 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 16 156 0 ENST00000328828.5:c.1069G>A p.Glu357Lys p.E357K ENST00000328828 NM_001101404.1 357 Gaa/Aaa 0 +SH3BGR UCSF GRCh37 21 40883652 40883652 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 10 35 0 ENST00000333634.4:c.670G>A p.Glu224Lys p.E224K ENST00000333634 NM_007341.2 224 Gag/Aag 0 +SHANK1 UCSF GRCh37 19 51170655 51170655 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 13 111 0 ENST00000293441.1:c.4562C>T p.Pro1521Leu p.P1521L ENST00000293441 NM_016148.2 1521 cCc/cTc 0 +SHANK1 UCSF GRCh37 19 51165271 51165271 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 321 38 488 0 ENST00000293441.1:c.6437G>A p.Gly2146Asp p.G2146D ENST00000293441 NM_016148.2 2146 gGc/gAc 0 +SHANK3 UCSF GRCh37 22 51154125 51154125 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 14 187 0 ENST00000262795.3:c.2342G>A p.Gly781Asp p.G781D ENST00000262795 NM_033517.1 781 gGc/gAc 0 +SHMT2 UCSF GRCh37 12 57625625 57625625 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 712 152 252 0 ENST00000328923.3:c.441C>T p.Asn147= p.N147= ENST00000328923 NM_005412.5 147 aaC/aaT 0 +SHROOM2 UCSF GRCh37 X 9900536 9900536 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 15 60 0 ENST00000380913.3:c.3213G>A p.Glu1071= p.E1071= ENST00000380913 NM_001649.2 1071 gaG/gaA 0 +SIGIRR UCSF GRCh37 11 406357 406357 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 15 124 0 ENST00000332725.3:c.1061G>A p.Gly354Asp p.G354D ENST00000332725 NM_001135053.1 354 gGc/gAc 0 +SIGLEC1 UCSF GRCh37 20 3670327 3670327 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 13 108 0 ENST00000344754.4:c.4917C>T p.Phe1639= p.F1639= ENST00000344754 NM_023068.3 1639 ttC/ttT 0 +SIGLEC1 UCSF GRCh37 20 3678704 3678704 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 12 54 0 ENST00000344754.4:c.1863C>T p.Leu621= p.L621= ENST00000344754 NM_023068.3 621 ctC/ctT 0 +SIGLEC10 UCSF GRCh37 19 51914392 51914392 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 207 44 364 0 ENST00000339313.5:c.2055G>A p.Lys685= p.K685= ENST00000339313 685 aaG/aaA 0 +SIK3 UCSF GRCh37 11 116741100 116741100 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 5 60 0 ENST00000292055.4:c.1581C>T p.Thr527= p.T527= ENST00000292055 NM_025164.3 527 acC/acT 0 +SIPA1L1 UCSF GRCh37 14 72055812 72055812 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 34 121 0 ENST00000555818.1:c.1223A>G p.Asn408Ser p.N408S ENST00000555818 NM_015556.1 408 aAt/aGt 0 +SIPA1L3 UCSF GRCh37 19 38643479 38643479 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 18 189 0 ENST00000222345.6:c.3534-1G>A p.X1178_splice ENST00000222345 NM_015073.1 0 +SIRT2 UCSF GRCh37 19 39384465 39384465 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 14 120 0 ENST00000249396.7:c.106G>A p.Ala36Thr p.A36T ENST00000249396 NM_012237.3 36 Gca/Aca 0 +SIRT6 UCSF GRCh37 19 4174726 4174726 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 8 48 0 ENST00000337491.2:c.956C>T p.Pro319Leu p.P319L ENST00000337491 NM_016539.2 319 cCc/cTc 0 +SIRT7 UCSF GRCh37 17 79870343 79870343 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 279 49 377 0 ENST00000328666.6:c.1152C>T p.Gly384= p.G384= ENST00000328666 NM_016538.2 384 ggC/ggT 0 +SIX5 UCSF GRCh37 19 46268871 46268871 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 23 237 0 ENST00000317578.6:c.2108G>A p.Gly703Glu p.G703E ENST00000317578 NM_175875.4 703 gGg/gAg 0 +SKI UCSF GRCh37 1 2160727 2160727 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 20 169 0 ENST00000378536.4:c.522C>T p.Cys174= p.C174= ENST00000378536 NM_003036.3 174 tgC/tgT 0 +SKI UCSF GRCh37 1 2235787 2235787 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 28 238 0 ENST00000378536.4:c.1530C>T p.Ala510= p.A510= ENST00000378536 NM_003036.3 510 gcC/gcT 0 +SKOR1 UCSF GRCh37 15 68121556 68121556 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 5 27 0 ENST00000380035.2:c.2356G>A p.Ala786Thr p.A786T ENST00000380035 786 Gcg/Acg 0 +SLC12A5 UCSF GRCh37 20 44669993 44669993 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 10 101 0 ENST00000454036.2:c.949C>T p.Leu317= p.L317= ENST00000454036 NM_001134771.1 317 Ctg/Ttg 0 +SLC12A8 UCSF GRCh37 3 124930185 124930185 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 16 165 0 ENST00000393469.4:c.9G>A p.Gln3= p.Q3= ENST00000393469 NM_001195483.1 3 caG/caA 0 +SLC13A3 UCSF GRCh37 20 45188771 45188771 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 12 62 0 ENST00000279027.4:c.1699G>A p.Ala567Thr p.A567T ENST00000279027 NM_001193342.1 567 Gca/Aca 0 +SLC14A2 UCSF GRCh37 18 43252921 43252921 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 371 61 548 0 ENST00000255226.6:c.2286G>A p.Trp762Ter p.W762* ENST00000255226 NM_007163.3 762 tgG/tgA 0 +SLC16A10 UCSF GRCh37 6 111409271 111409271 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 336 40 459 0 ENST00000368851.5:c.316G>A p.Asp106Asn p.D106N ENST00000368851 NM_018593.4 106 Gac/Aac 0 +SLC16A6 UCSF GRCh37 17 66267099 66267099 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 753 120 887 0 ENST00000327268.4:c.1202G>A p.Gly401Glu p.G401E ENST00000327268 NM_001174166.1 401 gGg/gAg 0 +SLC16A8 UCSF GRCh37 22 38477584 38477584 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 13 3 19 0 ENST00000320521.5:c.461C>T p.Pro154Leu p.P154L ENST00000320521 NM_013356.2 154 cCc/cTc 0 +SLC16A9 UCSF GRCh37 10 61413468 61413468 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 27 268 0 ENST00000395347.1:c.1316C>T p.Ala439Val p.A439V ENST00000395347 439 gCt/gTt 0 +SLC19A3 UCSF GRCh37 2 228564226 228564226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 7 120 0 ENST00000258403.3:c.205C>T p.Pro69Ser p.P69S ENST00000258403 NM_025243.3 69 Cct/Tct 0 +SLC1A2 UCSF GRCh37 11 35338955 35338955 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 7 69 0 ENST00000278379.3:c.126G>A p.Gly42= p.G42= ENST00000278379 NM_004171.3 42 ggG/ggA 0 +SLC22A10 UCSF GRCh37 11 63065069 63065069 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 41 157 0 ENST00000332793.6:c.700G>A p.Val234Ile p.V234I ENST00000332793 NM_001039752.3 234 Gta/Ata 0 +SLC22A8 UCSF GRCh37 11 62762159 62762159 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 21 199 0 ENST00000336232.2:c.1071C>T p.Ile357= p.I357= ENST00000336232 NM_001184736.1 357 atC/atT 0 +SLC25A17 UCSF GRCh37 22 41173090 41173090 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 12 62 0 ENST00000435456.2:c.647C>T p.Ala216Val p.A216V ENST00000435456 NM_006358.2 216 gCc/gTc 0 +SLC25A18 UCSF GRCh37 22 18070052 18070052 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 6 38 0 ENST00000327451.6:c.560G>A p.Gly187Asp p.G187D ENST00000327451 NM_031481.1 187 gGt/gAt 0 +SLC25A25 UCSF GRCh37 9 130866028 130866028 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 11 78 0 ENST00000373064.5:c.555G>A p.Met185Ile p.M185I ENST00000373064 NM_052901.4 185 atG/atA 0 +SLC25A31 UCSF GRCh37 4 128665894 128665894 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 20 247 0 ENST00000281154.4:c.300C>T p.Asn100= p.N100= ENST00000281154 NM_031291.2 100 aaC/aaT 0 +SLC25A33 UCSF GRCh37 1 9613713 9613713 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 16 129 0 ENST00000302692.6:c.86C>T p.Thr29Ile p.T29I ENST00000302692 NM_032315.2 29 aCt/aTt 0 +SLC25A42 UCSF GRCh37 19 19221405 19221405 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 12 56 0 ENST00000318596.7:c.677C>T p.Pro226Leu p.P226L ENST00000318596 NM_178526.4 226 cCc/cTc 0 +SLC26A10 UCSF GRCh37 12 58015596 58015596 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 668 99 174 0 ENST00000320442.4:c.679C>T p.Pro227Ser p.P227S ENST00000320442 NM_133489.2 227 Ccc/Tcc 0 +SLC26A2 UCSF GRCh37 5 149357587 149357587 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 65 231 0 ENST00000286298.4:c.372C>T p.Pro124= p.P124= ENST00000286298 NM_000112.3 124 ccC/ccT 0 +SLC26A3 UCSF GRCh37 7 107415274 107415274 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 196 32 301 0 ENST00000340010.5:c.1721C>T p.Ala574Val p.A574V ENST00000340010 NM_000111.2 574 gCt/gTt 0 +SLC26A8 UCSF GRCh37 6 35923186 35923186 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 28 269 0 ENST00000355574.2:c.1975G>A p.Asp659Asn p.D659N ENST00000355574 NM_001193476.1 659 Gac/Aac 0 +SLC27A1 UCSF GRCh37 19 17615328 17615328 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 21 188 0 ENST00000252595.7:c.1848C>T p.Asp616= p.D616= ENST00000252595 NM_198580.1 616 gaC/gaT 0 +SLC27A3 UCSF GRCh37 1 153747976 153747976 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 24 213 0 ENST00000368661.3:c.144G>A p.Met48Ile p.M48I ENST00000368661 NM_024330.1 48 atG/atA 0 +SLC27A4 UCSF GRCh37 9 131105537 131105537 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 7 50 0 ENST00000300456.4:c.126C>T p.Ile42= p.I42= ENST00000300456 NM_005094.3 42 atC/atT 0 +SLC27A5 UCSF GRCh37 19 59010240 59010240 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 62 165 1 ENST00000263093.2:c.1808C>T p.Pro603Leu p.P603L ENST00000263093 NM_012254.2 603 cCc/cTc 0 +SLC2A13 UCSF GRCh37 12 40258622 40258622 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 17 237 0 ENST00000280871.4:c.1261C>T p.Arg421Cys p.R421C ENST00000280871 NM_052885.3 421 Cgc/Tgc 0 +SLC2A8 UCSF GRCh37 9 130165022 130165022 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 55 0 ENST00000373371.3:c.713G>A p.Gly238Glu p.G238E ENST00000373371 NM_014580.4 238 gGg/gAg 0 +SLC34A1 UCSF GRCh37 5 176823753 176823753 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 23 138 0 ENST00000324417.5:c.1194C>T p.Thr398= p.T398= ENST00000324417 NM_003052.4 398 acC/acT 0 +SLC35E1 UCSF GRCh37 19 16664598 16664598 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 31 269 0 ENST00000595753.1:c.1125C>T p.Pro375= p.P375= ENST00000595753 NM_024881.4 375 ccC/ccT 0 +SLC37A1 UCSF GRCh37 21 43967234 43967234 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 270 45 353 0 ENST00000352133.2:c.752C>T p.Ser251Phe p.S251F ENST00000352133 251 tCc/tTc 0 +SLC38A5 UCSF GRCh37 X 48324630 48324630 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 17 40 0 ENST00000376876.3:c.399G>A p.Leu133= p.L133= ENST00000376876 133 ctG/ctA 0 +SLC45A3 UCSF GRCh37 1 205631136 205631136 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 7 35 0 ENST00000367145.3:c.1077G>A p.Val359= p.V359= ENST00000367145 NM_033102.2 359 gtG/gtA 0 +SLC46A2 UCSF GRCh37 9 115649617 115649617 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 15 148 0 ENST00000374228.4:c.1206C>T p.Ser402= p.S402= ENST00000374228 NM_033051.3 402 tcC/tcT 0 +SLC4A11 UCSF GRCh37 20 3211578 3211578 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 22 173 0 ENST00000380056.3:c.1216+1G>A p.X406_splice ENST00000380056 NM_032034.3 0 +SLC4A3 UCSF GRCh37 2 220498145 220498145 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 5 72 0 ENST00000317151.3:c.1427C>T p.Ala476Val p.A476V ENST00000317151 476 gCc/gTc 0 +SLC4A3 UCSF GRCh37 2 220502411 220502411 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 268 47 392 0 ENST00000317151.3:c.2644G>A p.Gly882Ser p.G882S ENST00000317151 882 Ggc/Agc 0 +SLC4A4 UCSF GRCh37 4 72413408 72413408 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 16 186 0 ENST00000264485.5:c.2665C>T p.Leu889= p.L889= ENST00000264485 NM_001098484.2 889 Ctg/Ttg 0 +SLC5A12 UCSF GRCh37 11 26743097 26743097 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 27 195 0 ENST00000396005.3:c.165G>A p.Leu55= p.L55= ENST00000396005 NM_178498.3 55 ttG/ttA 0 +SLC5A4 UCSF GRCh37 22 32628991 32628991 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 13 68 0 ENST00000266086.4:c.916G>A p.Asp306Asn p.D306N ENST00000266086 NM_014227.2 306 Gac/Aac 0 +SLC6A11 UCSF GRCh37 3 10861192 10861192 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 23 241 0 ENST00000254488.2:c.299G>A p.Gly100Glu p.G100E ENST00000254488 NM_014229.1 100 gGa/gAa 0 +SLC6A19 UCSF GRCh37 5 1208922 1208922 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 51 0 ENST00000304460.10:c.264G>A p.Leu88= p.L88= ENST00000304460 NM_001003841.2 88 ctG/ctA 0 +SLC6A4 UCSF GRCh37 17 28542628 28542628 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 24 239 0 ENST00000261707.3:c.1076+1G>A p.X359_splice ENST00000261707 NM_001045.5 0 +SLC7A14 UCSF GRCh37 3 170198521 170198521 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 207 34 293 0 ENST00000231706.5:c.1550C>T p.Thr517Ile p.T517I ENST00000231706 NM_020949.2 517 aCc/aTc 0 +SLC9A3 UCSF GRCh37 5 482251 482251 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 11 97 0 ENST00000264938.3:c.1378G>A p.Val460Met p.V460M ENST00000264938 NM_004174.2 460 Gtg/Atg 0 +SLC9A3R2 UCSF GRCh37 16 2086443 2086443 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 32 187 0 ENST00000424542.2:c.533C>T p.Ser178Phe p.S178F ENST00000424542 NM_001130012.2 178 tCt/tTt 0 +SLFN11 UCSF GRCh37 17 33689953 33689953 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 283 57 483 0 ENST00000308377.4:c.874C>T p.Pro292Ser p.P292S ENST00000308377 NM_152270.3 292 Ccg/Tcg 0 +SLITRK2 UCSF GRCh37 X 144905964 144905964 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 49 200 0 ENST00000370490.1:c.2021C>T p.Thr674Ile p.T674I ENST00000370490 674 aCt/aTt 0 +SLITRK3 UCSF GRCh37 3 164906241 164906241 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 27 266 0 ENST00000241274.3:c.2378G>A p.Gly793Glu p.G793E ENST00000241274 NM_014926.2 793 gGa/gAa 0 +SLMAP UCSF GRCh37 3 57843847 57843847 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 13 193 0 ENST00000428312.1:c.648G>A p.Arg216= p.R216= ENST00000428312 216 cgG/cgA 0 +SMAD9 UCSF GRCh37 13 37441475 37441475 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 9 90 0 ENST00000379826.4:c.716C>T p.Thr239Ile p.T239I ENST00000379826 NM_001127217.2 239 aCc/aTc 0 +SMARCA4 UCSF GRCh37 19 11132499 11132499 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 19 94 0 ENST00000344626.4:c.2715C>T p.Arg905= p.R905= ENST00000344626 NM_003072.3 905 cgC/cgT 0 +SMARCC2 UCSF GRCh37 12 56575805 56575805 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 21 188 0 ENST00000267064.4:c.691C>T p.Pro231Ser p.P231S ENST00000267064 NM_003075.3 231 Cct/Tct 0 +SMARCD2 UCSF GRCh37 17 61914339 61914339 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 20 145 0 ENST00000448276.2:c.510C>T p.Asp170= p.D170= ENST00000448276 NM_001098426.1 170 gaC/gaT 0 +SMCR7 UCSF GRCh37 17 18167100 18167100 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 42 0 ENST00000323019.4:c.387G>A p.Glu129= p.E129= ENST00000323019 NM_139162.3 129 gaG/gaA 0 +SMCR8 UCSF GRCh37 17 18221380 18221380 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 316 60 443 0 ENST00000406438.3:c.2277C>T p.Cys759= p.C759= ENST00000406438 NM_144775.2 759 tgC/tgT 0 +SMG6 UCSF GRCh37 17 1989101 1989101 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 22 95 0 ENST00000263073.6:c.3452G>A p.Gly1151Glu p.G1151E ENST00000263073 NM_017575.4 1151 gGa/gAa 0 +SMG8 UCSF GRCh37 17 57288108 57288108 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 500 77 697 1 ENST00000300917.5:c.696G>A p.Gly232= p.G232= ENST00000300917 NM_018149.6 232 ggG/ggA 0 +SMOC2 UCSF GRCh37 6 168949859 168949859 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 8 90 0 ENST00000356284.2:c.613C>T p.Gln205Ter p.Q205* ENST00000356284 NM_001166412.1 205 Cag/Tag 0 +SMTN UCSF GRCh37 22 31483980 31483980 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 9 93 0 ENST00000347557.2:c.81G>A p.Arg27= p.R27= ENST00000347557 NM_001207017.1 27 cgG/cgA 0 +SNAPC4 UCSF GRCh37 9 139277901 139277901 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 49 124 0 ENST00000298532.2:c.1720C>T p.Pro574Ser p.P574S ENST00000298532 NM_003086.2 574 Cct/Tct 0 +SNAPC4 UCSF GRCh37 9 139270934 139270934 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 14 59 0 ENST00000298532.2:c.4285-1G>A p.X1429_splice ENST00000298532 NM_003086.2 0 +SND1 UCSF GRCh37 7 127361376 127361376 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 52 168 0 ENST00000354725.3:c.1074G>A p.Val358= p.V358= ENST00000354725 NM_014390.2 358 gtG/gtA 0 +SNIP1 UCSF GRCh37 1 38006318 38006318 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 60 502 0 ENST00000296215.6:c.366G>A p.Arg122= p.R122= ENST00000296215 NM_024700.3 122 cgG/cgA 0 +SNRNP35 UCSF GRCh37 12 123950397 123950397 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 35 212 0 ENST00000350887.5:c.310G>A p.Ala104Thr p.A104T ENST00000350887 104 Gcc/Acc 0 +SNRNP70 UCSF GRCh37 19 49601749 49601749 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 11 58 0 ENST00000598441.1:c.330+1G>A p.X110_splice ENST00000598441 0 +SNTG2 UCSF GRCh37 2 1204830 1204830 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 9 121 0 ENST00000308624.5:c.633G>A p.Arg211= p.R211= ENST00000308624 NM_018968.3 211 agG/agA 0 +SNX16 UCSF GRCh37 8 82752050 82752050 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 24 273 0 ENST00000345957.4:c.172C>T p.Pro58Ser p.P58S ENST00000345957 NM_152836.2 58 Cct/Tct 0 +SNX27 UCSF GRCh37 1 151584906 151584906 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 19 118 0 ENST00000458013.2:c.229C>T p.Pro77Ser p.P77S ENST00000458013 77 Ccg/Tcg 0 +SNX29 UCSF GRCh37 16 12571605 12571605 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 20 124 0 ENST00000566228.1:c.2067G>A p.Trp689Ter p.W689* ENST00000566228 NM_032167.3 689 tgG/tgA 0 +SNX8 UCSF GRCh37 7 2314805 2314805 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 22 195 0 ENST00000222990.3:c.360C>T p.Leu120= p.L120= ENST00000222990 NM_013321.2 120 ctC/ctT 0 +SOBP UCSF GRCh37 6 107955882 107955882 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 16 124 0 ENST00000317357.5:c.1834C>T p.Pro612Ser p.P612S ENST00000317357 NM_018013.3 612 Ccc/Tcc 0 +SORBS1 UCSF GRCh37 10 97192287 97192287 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 6 103 0 ENST00000361941.3:c.219C>T p.Leu73= p.L73= ENST00000361941 NM_001034954.1 73 ctC/ctT 0 +SORBS3 UCSF GRCh37 8 22412459 22412459 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 8 47 0 ENST00000240123.7:c.186C>T p.Gly62= p.G62= ENST00000240123 NM_005775.4 62 ggC/ggT 0 +SORCS1 UCSF GRCh37 10 108366924 108366924 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 16 158 0 ENST00000263054.6:c.3165G>A p.Gln1055= p.Q1055= ENST00000263054 NM_001206570.1 1055 caG/caA 0 +SORL1 UCSF GRCh37 11 121498476 121498476 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 4 21 0 ENST00000260197.7:c.6577G>A p.Gly2193Arg p.G2193R ENST00000260197 NM_003105.5 2193 Ggg/Agg 0 +SOX11 UCSF GRCh37 2 5834108 5834108 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 30 184 0 ENST00000322002.3:c.1255C>T p.Pro419Ser p.P419S ENST00000322002 NM_003108.3 419 Ccg/Tcg 0 +SOX11 UCSF GRCh37 2 5833051 5833051 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 17 164 0 ENST00000322002.3:c.198G>A p.Lys66= p.K66= ENST00000322002 NM_003108.3 66 aaG/aaA 0 +SOX17 UCSF GRCh37 8 55370876 55370876 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 16 144 0 ENST00000297316.4:c.178G>A p.Gly60Ser p.G60S ENST00000297316 NM_022454.3 60 Ggc/Agc 0 +SOX4 UCSF GRCh37 6 21595585 21595585 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 71 0 ENST00000244745.1:c.820G>A p.Ala274Thr p.A274T ENST00000244745 NM_003107.2 274 Gca/Aca 0 +SP8 UCSF GRCh37 7 20824335 20824335 + missense_variant Missense_Mutation SNP G G C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 24 53 0 ENST00000361443.4:c.1047C>G p.Ser349Arg p.S349R ENST00000361443 NM_198956.2 349 agC/agG 0 +SPAG17 UCSF GRCh37 1 118539353 118539353 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 37 216 0 ENST00000336338.5:c.4790G>A p.Gly1597Asp p.G1597D ENST00000336338 NM_206996.2 1597 gGt/gAt 0 +SPAG17 UCSF GRCh37 1 118640307 118640307 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 40 317 0 ENST00000336338.5:c.997G>A p.Asp333Asn p.D333N ENST00000336338 NM_206996.2 333 Gat/Aat 0 +SPAM1 UCSF GRCh37 7 123593687 123593687 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 182 23 194 0 ENST00000223028.7:c.63C>T p.Ser21= p.S21= ENST00000223028 21 tcC/tcT 0 +SPATA13 UCSF GRCh37 13 24798455 24798455 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 18 113 0 ENST00000382095.4:c.-222-25160C>T *74* ENST00000382095 NM_153023.2 0 +SPATA21 UCSF GRCh37 1 16736310 16736310 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 28 174 0 ENST00000335496.1:c.373C>T p.Pro125Ser p.P125S ENST00000335496 NM_198546.1 125 Cca/Tca 0 +SPATA22 UCSF GRCh37 17 3346536 3346536 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 14 240 0 ENST00000397168.3:c.832C>T p.Pro278Ser p.P278S ENST00000397168 NM_032598.4 278 Cca/Tca 0 +SPATA5 UCSF GRCh37 4 123844347 123844347 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 241 46 315 0 ENST00000274008.4:c.50G>A p.Gly17Asp p.G17D ENST00000274008 NM_145207.2 17 gGt/gAt 0 +SPATS2 UCSF GRCh37 12 49883272 49883272 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 73 277 0 ENST00000321898.6:c.130C>T p.Pro44Ser p.P44S ENST00000321898 44 Cct/Tct 0 +SPATS2 UCSF GRCh37 12 49919843 49919843 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 29 202 0 ENST00000321898.6:c.1443G>A p.Trp481Ter p.W481* ENST00000321898 481 tgG/tgA 0 +SPEG UCSF GRCh37 2 220353344 220353344 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 13 127 0 ENST00000312358.7:c.7983C>T p.Asn2661= p.N2661= ENST00000312358 NM_005876.4 2661 aaC/aaT 0 +SPINT3 UCSF GRCh37 20 44144178 44144178 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 92 292 0 ENST00000217428.6:c.71C>T p.Ala24Val p.A24V ENST00000217428 NM_006652.1 24 gCa/gTa 0 +SPNS1 UCSF GRCh37 16 28993752 28993752 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 24 127 0 ENST00000311008.11:c.1041C>T p.Leu347= p.L347= ENST00000311008 NM_032038.2 347 ctC/ctT 0 +SPOPL UCSF GRCh37 2 139308548 139308548 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 15 124 0 ENST00000280098.4:c.276C>T p.Ser92= p.S92= ENST00000280098 NM_001001664.2 92 agC/agT 0 +SPRYD4 UCSF GRCh37 12 56863083 56863083 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 28 172 0 ENST00000338146.5:c.346G>A p.Gly116Ser p.G116S ENST00000338146 NM_207344.3 116 Ggt/Agt 0 +SPSB4 UCSF GRCh37 3 140784965 140784965 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 6 30 0 ENST00000310546.2:c.19G>A p.Gly7Arg p.G7R ENST00000310546 NM_080862.1 7 Ggg/Agg 0 +SPTAN1 UCSF GRCh37 9 131388710 131388710 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 74 0 ENST00000372731.4:c.6305C>T p.Ala2102Val p.A2102V ENST00000372731 NM_003127.3 2102 gCc/gTc 0 +SPTB UCSF GRCh37 14 65216827 65216827 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 25 164 0 ENST00000389722.3:c.6648C>T p.Thr2216= p.T2216= ENST00000389722 NM_001024858.2 2216 acC/acT 0 +SPTBN1 UCSF GRCh37 2 54876290 54876290 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 6 17 0 ENST00000356805.4:c.5165G>A p.Gly1722Glu p.G1722E ENST00000356805 NM_003128.2 1722 gGg/gAg 0 +SPTBN2 UCSF GRCh37 11 66481114 66481114 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 17 187 0 ENST00000309996.2:c.760C>T p.Leu254= p.L254= ENST00000309996 NM_006946.2 254 Ctg/Ttg 0 +SPTBN2 UCSF GRCh37 11 66466553 66466553 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 363 58 456 0 ENST00000309996.2:c.3777G>A p.Arg1259= p.R1259= ENST00000309996 NM_006946.2 1259 agG/agA 0 +SPTBN4 UCSF GRCh37 19 41021267 41021267 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 6 28 0 ENST00000352632.3:c.2815G>A p.Asp939Asn p.D939N ENST00000352632 939 Gac/Aac 0 +SPTBN4 UCSF GRCh37 19 40993674 40993674 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 7 57 0 ENST00000352632.3:c.240C>T p.Cys80= p.C80= ENST00000352632 80 tgC/tgT 0 +SPTBN5 UCSF GRCh37 15 42144889 42144889 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 59 174 0 ENST00000320955.6:c.10392C>T p.Asp3464= p.D3464= ENST00000320955 NM_016642.3 3464 gaC/gaT 0 +SQSTM1 UCSF GRCh37 5 179250015 179250015 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 20 145 0 ENST00000389805.4:c.263C>T p.Ser88Phe p.S88F ENST00000389805 NM_003900.4 88 tCc/tTc 0 +SRCAP UCSF GRCh37 16 30715577 30715577 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 18 168 0 ENST00000262518.4:c.247G>A p.Ala83Thr p.A83T ENST00000262518 NM_006662.2 83 Gct/Act 0 +SREBF2 UCSF GRCh37 22 42280908 42280908 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 9 80 0 ENST00000361204.4:c.2101G>A p.Ala701Thr p.A701T ENST00000361204 NM_004599.3 701 Gct/Act 0 +SREBF2 UCSF GRCh37 22 42263059 42263059 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 417 70 556 0 ENST00000361204.4:c.313G>A p.Ala105Thr p.A105T ENST00000361204 NM_004599.3 105 Gcc/Acc 0 +SRGAP1 UCSF GRCh37 12 64536324 64536324 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 35 279 0 ENST00000355086.3:c.3130C>T p.Pro1044Ser p.P1044S ENST00000355086 NM_020762.2 1044 Ccc/Tcc 0 +SRGAP1 UCSF GRCh37 12 64410738 64410738 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 15 181 0 ENST00000355086.3:c.435G>A p.Glu145= p.E145= ENST00000355086 NM_020762.2 145 gaG/gaA 0 +SRM UCSF GRCh37 1 11116668 11116668 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 11 73 0 ENST00000376957.2:c.528C>T p.Asp176= p.D176= ENST00000376957 NM_003132.2 176 gaC/gaT 0 +SRRM2 UCSF GRCh37 16 2819002 2819002 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 84 216 0 ENST00000301740.8:c.7738C>T p.Pro2580Ser p.P2580S ENST00000301740 NM_016333.3 2580 Ccc/Tcc 0 +SRRM2 UCSF GRCh37 16 2806587 2806587 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 25 64 0 ENST00000301740.8:c.222G>A p.Glu74= p.E74= ENST00000301740 NM_016333.3 74 gaG/gaA 0 +SRRM3 UCSF GRCh37 7 75877587 75877587 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 6 26 0 ENST00000326382.8:c.315G>A p.Glu105= p.E105= ENST00000326382 NM_001110199.1 105 gaG/gaA 0 +SRRM5 UCSF GRCh37 19 44118416 44118416 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 20 146 0 ENST00000300811.3:c.41C>T p.Ala14Val p.A14V ENST00000300811 NM_182498.3 14 gCc/gTc 0 +SRY UCSF GRCh37 Y 2655091 2655091 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 17 113 0 ENST00000383070.1:c.554C>T p.Pro185Leu p.P185L ENST00000383070 NM_003140.2 185 cCc/cTc 0 +SSPN UCSF GRCh37 12 26348790 26348790 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 17 118 0 ENST00000242729.2:c.185C>T p.Ala62Val p.A62V ENST00000242729 NM_005086.4 62 gCc/gTc 0 +SSPO UCSF GRCh37 7 149488952 149488952 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 17 127 0 ENST00000378016.2:n.5293C>T *1765* ENST00000378016 0 +SSPO UCSF GRCh37 7 149479365 149479365 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 26 206 0 ENST00000378016.2:n.1878C>T *626* ENST00000378016 0 +SSTR1 UCSF GRCh37 14 38679367 38679367 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 62 205 0 ENST00000267377.2:c.773G>A p.Gly258Asp p.G258D ENST00000267377 NM_001049.2 258 gGc/gAc 0 +ST14 UCSF GRCh37 11 130068262 130068262 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 9 86 0 ENST00000278742.5:c.1519G>A p.Val507Ile p.V507I ENST00000278742 NM_021978.3 507 Gtc/Atc 0 +ST6GAL1 UCSF GRCh37 3 186760523 186760523 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 27 242 0 ENST00000169298.3:c.32G>A p.Ser11Asn p.S11N ENST00000169298 NM_173216.2 11 aGc/aAc 0 +ST6GALNAC1 UCSF GRCh37 17 74622111 74622111 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 18 104 0 ENST00000156626.7:c.1482C>T p.Asp494= p.D494= ENST00000156626 NM_018414.3 494 gaC/gaT 0 +STAB1 UCSF GRCh37 3 52554234 52554234 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 444 77 586 0 ENST00000321725.6:c.5427C>T p.Asp1809= p.D1809= ENST00000321725 NM_015136.2 1809 gaC/gaT 0 +STAG1 UCSF GRCh37 3 136068156 136068156 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 9 88 0 ENST00000383202.2:c.3115G>A p.Glu1039Lys p.E1039K ENST00000383202 NM_005862.2 1039 Gag/Aag 0 +STAG1 UCSF GRCh37 3 136136787 136136787 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 29 276 0 ENST00000383202.2:c.2136C>T p.Leu712= p.L712= ENST00000383202 NM_005862.2 712 ctC/ctT 0 +STARD7 UCSF GRCh37 2 96859011 96859011 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 214 34 361 0 ENST00000337288.5:c.629C>T p.Ser210Phe p.S210F ENST00000337288 NM_020151.3 210 tCc/tTc 0 +STAT5A UCSF GRCh37 17 40458446 40458446 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 4 22 0 ENST00000345506.4:c.1661C>T p.Ser554Phe p.S554F ENST00000345506 NM_003152.3 554 tCc/tTc 0 +STC2 UCSF GRCh37 5 172755116 172755116 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 79 289 0 ENST00000265087.4:c.81C>T p.Ala27= p.A27= ENST00000265087 NM_003714.2 27 gcC/gcT 0 +STIM2 UCSF GRCh37 4 27024410 27024410 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 369 67 566 0 ENST00000467087.1:c.2033C>T p.Ser678Phe p.S678F ENST00000467087 NM_020860.3 678 tCc/tTc 0 +STIM2 UCSF GRCh37 4 27004714 27004714 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 6 57 0 ENST00000467087.1:c.969G>A p.Gln323= p.Q323= ENST00000467087 NM_020860.3 323 caG/caA 0 +STK10 UCSF GRCh37 5 171510076 171510076 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 15 112 0 ENST00000176763.5:c.1698C>T p.Leu566= p.L566= ENST00000176763 NM_005990.3 566 ctC/ctT 0 +STK25 UCSF GRCh37 2 242441087 242441087 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0010 P24_Rec2 Untested WXS Illumina HiSeq 235 42 378 0 ENST00000316586.4:c.67C>T p.Leu23Phe p.L23F ENST00000316586 NM_001282308.1 23 Ctc/Ttc 0 +STK4 UCSF GRCh37 20 43615866 43615866 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 24 225 0 ENST00000372806.3:c.454G>A p.Ala152Thr p.A152T ENST00000372806 NM_006282.2 152 Gca/Aca 0 +STK4 UCSF GRCh37 20 43623731 43623731 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 18 131 0 ENST00000372806.3:c.526G>A p.Asp176Asn p.D176N ENST00000372806 NM_006282.2 176 Gat/Aat 0 +STON1 UCSF GRCh37 2 48807954 48807954 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 296 45 506 0 ENST00000309835.3:c.182C>T p.Pro61Leu p.P61L ENST00000309835 61 cCt/cTt 0 +STT3A UCSF GRCh37 11 125482999 125482999 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 182 23 265 0 ENST00000392708.4:c.1481G>A p.Gly494Asp p.G494D ENST00000392708 NM_001278503.1 494 gGt/gAt 0 +STX17 UCSF GRCh37 9 102713352 102713352 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 123 23 191 0 ENST00000259400.6:c.200C>T p.Ser67Phe p.S67F ENST00000259400 NM_017919.2 67 tCc/tTc 0 +STX18 UCSF GRCh37 4 4440217 4440217 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 84 209 0 ENST00000306200.2:c.517C>T p.Pro173Ser p.P173S ENST00000306200 NM_016930.2 173 Cca/Tca 0 +STXBP5 UCSF GRCh37 6 147680301 147680301 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 24 242 0 ENST00000321680.6:c.2387C>T p.Ala796Val p.A796V ENST00000321680 NM_001127715.2 796 gCt/gTt 0 +STXBP5L UCSF GRCh37 3 120973866 120973866 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 16 157 0 ENST00000273666.6:c.1566G>A p.Trp522Ter p.W522* ENST00000273666 NM_014980.2 522 tgG/tgA 0 +SUGP2 UCSF GRCh37 19 19115330 19115330 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 573 83 621 0 ENST00000337018.6:c.2576G>A p.Gly859Asp p.G859D ENST00000337018 NM_014884.3 859 gGt/gAt 0 +SULT1C2 UCSF GRCh37 2 108921630 108921630 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 7 59 0 ENST00000251481.6:c.505G>A p.Val169Ile p.V169I ENST00000251481 NM_001056.3 169 Gtt/Att 0 +SUOX UCSF GRCh37 12 56397638 56397638 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 118 354 0 ENST00000266971.3:c.465C>T p.Tyr155= p.Y155= ENST00000266971 NM_001032386.1 155 taC/taT 0 +SUPV3L1 UCSF GRCh37 10 70949174 70949174 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 8 86 0 ENST00000359655.4:c.724G>A p.Glu242Lys p.E242K ENST00000359655 NM_003171.3 242 Gaa/Aaa 0 +SURF2 UCSF GRCh37 9 136226929 136226929 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 8 89 0 ENST00000371964.4:c.441G>A p.Arg147= p.R147= ENST00000371964 NM_001278928.1 147 cgG/cgA 0 +SUV420H1 UCSF GRCh37 11 67926313 67926313 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 15 132 0 ENST00000304363.4:c.1500C>T p.Ala500= p.A500= ENST00000304363 NM_017635.3 500 gcC/gcT 0 +SV2B UCSF GRCh37 15 91769927 91769927 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 110 0 ENST00000330276.4:c.434C>T p.Ser145Phe p.S145F ENST00000330276 145 tCc/tTc 0 +SWT1 UCSF GRCh37 1 185259900 185259900 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 12 145 0 ENST00000367500.4:c.2668G>A p.Gly890Arg p.G890R ENST00000367500 NM_017673.6 890 Gga/Aga 0 +SYAP1 UCSF GRCh37 X 16773095 16773095 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 18 80 0 ENST00000380155.3:c.603C>T p.Asn201= p.N201= ENST00000380155 NM_032796.3 201 aaC/aaT 0 +SYMPK UCSF GRCh37 19 46331177 46331177 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 9 83 0 ENST00000245934.7:c.1986-1G>A p.X662_splice ENST00000245934 NM_004819.2 0 +SYMPK UCSF GRCh37 19 46355767 46355767 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 271 38 422 0 ENST00000245934.7:c.198C>T p.Asp66= p.D66= ENST00000245934 NM_004819.2 66 gaC/gaT 0 +SYN1 UCSF GRCh37 X 47478988 47478988 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 4 55 0 ENST00000295987.7:c.140G>A p.Gly47Glu p.G47E ENST00000295987 NM_006950.3 47 gGg/gAg 0 +SYNE1 UCSF GRCh37 6 152725353 152725353 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 23 101 0 ENST00000367255.5:c.6820C>A p.Leu2274Ile p.L2274I ENST00000367255 NM_182961.3 2274 Ctt/Att 0 +SYNE1 UCSF GRCh37 6 152665324 152665324 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 19 89 0 ENST00000367255.5:c.12117C>T p.Val4039= p.V4039= ENST00000367255 NM_182961.3 4039 gtC/gtT 0 +SYNE2 UCSF GRCh37 14 64626029 64626029 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 22 178 0 ENST00000344113.4:c.15964-1G>A p.X5322_splice ENST00000344113 NM_015180.4 0 +SYT16 UCSF GRCh37 14 62547594 62547594 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 14 75 0 ENST00000430451.2:c.1036G>A p.Glu346Lys p.E346K ENST00000430451 NM_031914.2 346 Gag/Aag 0 +SYT5 UCSF GRCh37 19 55686648 55686648 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 26 153 1 ENST00000354308.3:c.600C>T p.Arg200= p.R200= ENST00000354308 NM_003180.2 200 cgC/cgT 0 +SYT9 UCSF GRCh37 11 7324534 7324534 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 13 71 0 ENST00000318881.6:c.410C>T p.Pro137Leu p.P137L ENST00000318881 NM_175733.3 137 cCc/cTc 0 +SZT2 UCSF GRCh37 1 43893377 43893377 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 6 48 0 ENST00000562955.1:c.3604C>T p.Pro1202Ser p.P1202S ENST00000562955 NM_015284.3 1202 Cct/Tct 0 +SZT2 UCSF GRCh37 1 43894075 43894075 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 17 97 0 ENST00000562955.1:c.3913C>T p.Pro1305Ser p.P1305S ENST00000562955 NM_015284.3 1305 Cct/Tct 0 +SZT2 UCSF GRCh37 1 43898012 43898012 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 25 239 0 ENST00000562955.1:c.5173G>A p.Ala1725Thr p.A1725T ENST00000562955 NM_015284.3 1725 Gca/Aca 0 +SZT2 UCSF GRCh37 1 43911930 43911930 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 12 144 0 ENST00000562955.1:c.8826G>A p.Gln2942= p.Q2942= ENST00000562955 NM_015284.3 2942 caG/caA 0 +TAAR9 UCSF GRCh37 6 132859688 132859688 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 315 52 425 0 ENST00000434551.1:c.260C>T p.Pro87Leu p.P87L ENST00000434551 NM_175057.3 87 cCc/cTc 0 +TAAR9 UCSF GRCh37 6 132859645 132859645 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 312 49 408 0 ENST00000434551.1:c.217T>C p.Ser73Pro p.S73P ENST00000434551 NM_175057.3 73 Tcg/Ccg 0 +TACC1 UCSF GRCh37 8 38699936 38699936 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 21 131 0 ENST00000317827.4:c.2092C>G p.Leu698Val p.L698V ENST00000317827 NM_006283.2 698 Ctg/Gtg 0 +TACC3 UCSF GRCh37 4 1739337 1739337 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 15 120 0 ENST00000313288.4:c.1849C>T p.Pro617Ser p.P617S ENST00000313288 NM_006342.2 617 Ccc/Tcc 0 +TACR3 UCSF GRCh37 4 104579464 104579464 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 68 240 0 ENST00000304883.2:c.645C>T p.Ala215= p.A215= ENST00000304883 NM_001059.2 215 gcC/gcT 0 +TACSTD2 UCSF GRCh37 1 59042226 59042226 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 23 224 0 ENST00000371225.2:c.603C>T p.Ile201= p.I201= ENST00000371225 NM_002353.2 201 atC/atT 0 +TACSTD2 UCSF GRCh37 1 59042664 59042664 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 13 108 0 ENST00000371225.2:c.165C>T p.Cys55= p.C55= ENST00000371225 NM_002353.2 55 tgC/tgT 0 +TADA2B UCSF GRCh37 4 7056411 7056411 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 14 144 0 ENST00000310074.7:c.893G>A p.Gly298Glu p.G298E ENST00000310074 NM_152293.2 298 gGg/gAg 0 +TADA3 UCSF GRCh37 3 9829012 9829012 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 9 70 0 ENST00000301964.2:c.577G>A p.Gly193Arg p.G193R ENST00000301964 NM_006354.3 193 Ggg/Agg 0 +TAF9 UCSF GRCh37 5 68661436 68661436 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 341 45 482 0 ENST00000217893.5:c.129C>T p.Ala43= p.A43= ENST00000217893 NM_003187.4 43 gcC/gcT 0 +TAOK3 UCSF GRCh37 12 118590125 118590125 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 405 76 566 0 ENST00000392533.3:c.2442C>T p.Ser814= p.S814= ENST00000392533 NM_016281.3 814 agC/agT 0 +TAP2 UCSF GRCh37 6 32800159 32800159 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 30 202 0 ENST00000374897.2:c.1223G>A p.Ser408Asn p.S408N ENST00000374897 NM_000544.3 408 aGc/aAc 0 +TAP2 UCSF GRCh37 6 32805988 32805988 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 7 43 0 ENST00000374897.2:c.23C>T p.Pro8Leu p.P8L ENST00000374897 NM_000544.3 8 cCc/cTc 0 +TARS UCSF GRCh37 5 33462252 33462252 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 18 79 0 ENST00000265112.3:c.1779C>T p.Ile593= p.I593= ENST00000265112 NM_152295.4 593 atC/atT 0 +TAS1R2 UCSF GRCh37 1 19166441 19166441 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 24 183 0 ENST00000375371.3:c.2172C>T p.Tyr724= p.Y724= ENST00000375371 NM_152232.2 724 taC/taT 0 +TAS2R16 UCSF GRCh37 7 122634918 122634918 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 342 45 394 0 ENST00000249284.2:c.771G>A p.Trp257Ter p.W257* ENST00000249284 NM_016945.2 257 tgG/tgA 0 +TBC1D1 UCSF GRCh37 4 38138876 38138876 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 9 52 0 ENST00000261439.4:c.3427G>A p.Val1143Met p.V1143M ENST00000261439 NM_015173.3 1143 Gtg/Atg 0 +TBC1D16 UCSF GRCh37 17 77984245 77984245 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 17 140 0 ENST00000310924.2:c.493G>A p.Ala165Thr p.A165T ENST00000310924 NM_019020.3 165 Gcg/Acg 0 +TBC1D24 UCSF GRCh37 16 2548302 2548302 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 144 17 161 0 ENST00000293970.5:c.1047G>A p.Glu349= p.E349= ENST00000293970 NM_001199107.1 349 gaG/gaA 0 +TBC1D24 UCSF GRCh37 16 2549836 2549836 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 27 73 0 ENST00000293970.5:c.1207G>A p.Val403Met p.V403M ENST00000293970 NM_001199107.1 403 Gtg/Atg 0 +TBC1D2B UCSF GRCh37 15 78369778 78369778 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 4 35 0 ENST00000300584.3:c.217C>T p.Pro73Ser p.P73S ENST00000300584 NM_144572.1 73 Ccg/Tcg 0 +TBC1D9 UCSF GRCh37 4 141543756 141543756 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 24 253 0 ENST00000442267.2:c.3394G>A p.Asp1132Asn p.D1132N ENST00000442267 NM_015130.2 1132 Gac/Aac 0 +TBX19 UCSF GRCh37 1 168260609 168260609 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 12 74 0 ENST00000367821.3:c.415C>T p.Pro139Ser p.P139S ENST00000367821 NM_005149.2 139 Ccc/Tcc 0 +TBX20 UCSF GRCh37 7 35289735 35289735 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 5 47 0 ENST00000408931.3:c.208G>A p.Gly70Ser p.G70S ENST00000408931 NM_001077653.2 70 Ggc/Agc 0 +TBX4 UCSF GRCh37 17 59534957 59534957 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 15 90 0 ENST00000240335.1:c.246G>A p.Glu82= p.E82= ENST00000240335 NM_018488.2 82 gaG/gaA 0 +TCF25 UCSF GRCh37 16 89954120 89954120 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 3 68 0 ENST00000263346.8:c.609G>A p.Glu203= p.E203= ENST00000263346 NM_014972.2 203 gaG/gaA 0 +TCF7L1 UCSF GRCh37 2 85532455 85532455 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 38 199 0 ENST00000282111.3:c.918C>T p.Pro306= p.P306= ENST00000282111 NM_031283.2 306 ccC/ccT 0 +TCFL5 UCSF GRCh37 20 61488834 61488834 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 305 83 457 0 ENST00000335351.3:c.1151C>T p.Ala384Val p.A384V ENST00000335351 NM_006602.2 384 gCa/gTa 0 +TCHH UCSF GRCh37 1 152083914 152083914 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 480 100 754 0 ENST00000368804.1:c.1779G>A p.Glu593= p.E593= ENST00000368804 NM_007113.3 593 gaG/gaA 0 +TCIRG1 UCSF GRCh37 11 67815257 67815257 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 18 134 0 ENST00000265686.3:c.1449C>T p.Asn483= p.N483= ENST00000265686 NM_006019.3 483 aaC/aaT 0 +TCN2 UCSF GRCh37 22 31010439 31010439 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 8 48 0 ENST00000215838.3:c.531C>T p.Asp177= p.D177= ENST00000215838 177 gaC/gaT 0 +TCTE1 UCSF GRCh37 6 44250156 44250156 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 17 112 0 ENST00000371505.4:c.987G>A p.Lys329= p.K329= ENST00000371505 NM_182539.3 329 aaG/aaA 0 +TDP1 UCSF GRCh37 14 90429642 90429642 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 23 153 0 ENST00000335725.4:c.184C>T p.Pro62Ser p.P62S ENST00000335725 NM_018319.3 62 Cct/Tct 0 +TDRD7 UCSF GRCh37 9 100222459 100222459 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 22 85 0 ENST00000355295.4:c.856-1G>A p.X286_splice ENST00000355295 NM_014290.2 0 +TDRD9 UCSF GRCh37 14 104484461 104484461 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 8 105 0 ENST00000409874.4:c.2364C>T p.Tyr788= p.Y788= ENST00000409874 NM_153046.2 788 taC/taT 0 +TEC 7006 UCSF GRCh37 4 48230504 48230504 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 10 87 0 ENST00000381501.3:c.128G>A p.Gly43Asp p.G43D ENST00000381501 NM_003215.2 43 gGt/gAt 0 +TEKT3 UCSF GRCh37 17 15231345 15231345 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 27 193 0 ENST00000338696.2:c.627C>T p.Asp209= p.D209= ENST00000338696 209 gaC/gaT 0 +TEKT4 UCSF GRCh37 2 95542486 95542486 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 19 272 0 ENST00000295201.4:c.1280C>T p.Thr427Ile p.T427I ENST00000295201 NM_144705.2 427 aCc/aTc 0 +TET1 UCSF GRCh37 10 70412308 70412308 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 19 148 0 ENST00000373644.4:c.4418G>A p.Gly1473Asp p.G1473D ENST00000373644 NM_030625.2 1473 gGt/gAt 0 +TFAP2A UCSF GRCh37 6 10410254 10410254 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 19 126 0 ENST00000482890.1:c.360C>T p.Gly120= p.G120= ENST00000482890 120 ggC/ggT 0 +TFAP2D UCSF GRCh37 6 50712900 50712900 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 29 131 0 ENST00000008391.3:c.964G>A p.Ala322Thr p.A322T ENST00000008391 NM_172238.3 322 Gcc/Acc 0 +TFE3 UCSF GRCh37 X 48891659 48891659 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 19 87 0 ENST00000315869.7:c.993G>A p.Arg331= p.R331= ENST00000315869 NM_006521.4 331 cgG/cgA 0 +TGFB1 UCSF GRCh37 19 41858729 41858729 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 15 62 0 ENST00000221930.5:c.221C>T p.Pro74Leu p.P74L ENST00000221930 NM_000660.4 74 cCc/cTc 0 +THAP10 UCSF GRCh37 15 71184308 71184308 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 8 90 0 ENST00000249861.4:c.304G>A p.Glu102Lys p.E102K ENST00000249861 NM_020147.3 102 Gag/Aag 0 +THAP8 UCSF GRCh37 19 36526365 36526365 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 23 186 0 ENST00000292894.1:c.802G>A p.Asp268Asn p.D268N ENST00000292894 NM_152658.2 268 Gac/Aac 0 +THBS2 UCSF GRCh37 6 169646295 169646295 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 11 112 0 ENST00000366787.3:c.691G>A p.Gly231Arg p.G231R ENST00000366787 NM_003247.2 231 Gga/Aga 0 +THBS2 UCSF GRCh37 6 169622376 169622376 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 9 72 0 ENST00000366787.3:c.3189G>A p.Val1063= p.V1063= ENST00000366787 NM_003247.2 1063 gtG/gtA 0 +THBS3 UCSF GRCh37 1 155172176 155172176 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 19 130 0 ENST00000368378.3:c.974C>T p.Pro325Leu p.P325L ENST00000368378 NM_007112.4 325 cCc/cTc 0 +THRAP3 UCSF GRCh37 1 36752234 36752234 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 229 140 422 0 ENST00000354618.5:c.403C>T p.Pro135Ser p.P135S ENST00000354618 NM_005119.3 135 Cct/Tct 0 +THSD7B UCSF GRCh37 2 137990496 137990496 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 26 192 0 ENST00000272643.3:c.1943C>T p.Ala648Val p.A648V ENST00000272643 648 gCt/gTt 0 +THSD7B UCSF GRCh37 2 138378229 138378229 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 11 134 1 ENST00000272643.3:c.3741C>T p.Cys1247= p.C1247= ENST00000272643 1247 tgC/tgT 0 +TIAM1 UCSF GRCh37 21 32617945 32617945 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 11 94 0 ENST00000286827.3:c.1443C>T p.Gly481= p.G481= ENST00000286827 NM_003253.2 481 ggC/ggT 0 +TIAM2 UCSF GRCh37 6 155577830 155577830 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 10 62 0 ENST00000318981.5:c.4681C>T p.Leu1561Phe p.L1561F ENST00000318981 NM_012454.3 1561 Ctc/Ttc 0 +TIGD5 UCSF GRCh37 8 144680968 144680968 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 23 166 0 ENST00000321385.3:c.748G>A p.Asp250Asn p.D250N ENST00000321385 250 Gac/Aac 0 +TIGD6 UCSF GRCh37 5 149375414 149375414 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 339 48 567 0 ENST00000296736.3:c.498G>A p.Leu166= p.L166= ENST00000296736 NM_030953.3 166 ctG/ctA 0 +TIMELESS UCSF GRCh37 12 56822416 56822416 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 8 47 0 ENST00000553532.1:c.1325C>T p.Ala442Val p.A442V ENST00000553532 442 gCc/gTc 0 +TIMP3 UCSF GRCh37 22 33255238 33255238 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 16 142 0 ENST00000266085.6:c.510C>T p.Ser170= p.S170= ENST00000266085 NM_000362.4 170 tcC/tcT 0 +TINAG UCSF GRCh37 6 54212223 54212223 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 26 233 0 ENST00000259782.4:c.807C>T p.Ser269= p.S269= ENST00000259782 NM_014464.3 269 tcC/tcT 0 +TINAG UCSF GRCh37 6 54185408 54185408 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 17 175 0 ENST00000259782.4:c.387G>A p.Glu129= p.E129= ENST00000259782 NM_014464.3 129 gaG/gaA 0 +TKT UCSF GRCh37 3 53275214 53275214 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 25 258 0 ENST00000423525.2:c.273C>T p.Phe91= p.F91= ENST00000423525 NM_001135055.2 91 ttC/ttT 0 +TLCD1 UCSF GRCh37 17 27051565 27051565 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 26 142 0 ENST00000292090.3:c.707C>T p.Pro236Leu p.P236L ENST00000292090 NM_138463.3 236 cCc/cTc 0 +TLE1 UCSF GRCh37 9 84200524 84200524 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 5 70 0 ENST00000376499.3:c.2024G>A p.Gly675Asp p.G675D ENST00000376499 NM_005077.3 675 gGc/gAc 0 +TLE1 UCSF GRCh37 9 84249150 84249150 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 29 77 0 ENST00000376499.3:c.439C>T p.Pro147Ser p.P147S ENST00000376499 NM_005077.3 147 Cct/Tct 0 +TLK2 UCSF GRCh37 17 60598179 60598179 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 4 34 0 ENST00000326270.9:c.127G>A p.Gly43Arg p.G43R ENST00000326270 NM_001284333.1 43 Gga/Aga 0 +TLK2 UCSF GRCh37 17 60598172 60598172 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 4 35 1 ENST00000326270.9:c.120C>T p.Cys40= p.C40= ENST00000326270 NM_001284333.1 40 tgC/tgT 0 +TLN1 UCSF GRCh37 9 35711782 35711782 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 32 282 0 ENST00000314888.9:c.3689C>T p.Pro1230Leu p.P1230L ENST00000314888 NM_006289.3 1230 cCt/cTt 0 +TLX2 UCSF GRCh37 2 74742762 74742762 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 15 119 0 ENST00000233638.7:c.403G>A p.Ala135Thr p.A135T ENST00000233638 NM_016170.4 135 Gcg/Acg 0 +TM2D1 UCSF GRCh37 1 62175098 62175098 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 16 191 1 ENST00000294613.5:c.250C>T p.Pro84Ser p.P84S ENST00000294613 84 Cca/Tca 0 +TM4SF5 UCSF GRCh37 17 4675277 4675277 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 39 253 1 ENST00000270560.3:c.60C>T p.Val20= p.V20= ENST00000270560 NM_003963.2 20 gtC/gtT 0 +TM9SF2 UCSF GRCh37 13 100206648 100206648 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 31 283 0 ENST00000376387.4:c.1579G>A p.Gly527Arg p.G527R ENST00000376387 NM_004800.2 527 Gga/Aga 0 +TMC6 UCSF GRCh37 17 76122428 76122428 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 14 108 0 ENST00000322914.3:c.201C>T p.Leu67= p.L67= ENST00000322914 NM_007267.6 67 ctC/ctT 0 +TMC7 UCSF GRCh37 16 19033040 19033040 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 9 119 0 ENST00000304381.5:c.550C>T p.Leu184= p.L184= ENST00000304381 NM_024847.3 184 Ctg/Ttg 0 +TMCC2 UCSF GRCh37 1 205238657 205238657 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 192 24 295 0 ENST00000358024.3:c.1327G>A p.Ala443Thr p.A443T ENST00000358024 NM_014858.3 443 Gcc/Acc 0 +TMED3 UCSF GRCh37 15 79614385 79614385 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 15 155 0 ENST00000299705.5:c.483C>T p.Tyr161= p.Y161= ENST00000299705 NM_007364.2 161 taC/taT 0 +TMEM119 UCSF GRCh37 12 108985533 108985533 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 244 40 321 0 ENST00000392806.3:c.627G>A p.Glu209= p.E209= ENST00000392806 NM_181724.2 209 gaG/gaA 0 +TMEM130 UCSF GRCh37 7 98460878 98460878 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 24 259 0 ENST00000416379.2:c.231C>T p.Thr77= p.T77= ENST00000416379 77 acC/acT 0 +TMEM132D UCSF GRCh37 12 130184605 130184605 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 242 45 355 0 ENST00000422113.2:c.718G>A p.Val240Ile p.V240I ENST00000422113 NM_133448.2 240 Gtc/Atc 0 +TMEM132D UCSF GRCh37 12 130185023 130185023 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 29 235 0 ENST00000422113.2:c.300C>T p.Phe100= p.F100= ENST00000422113 NM_133448.2 100 ttC/ttT 0 +TMEM132E UCSF GRCh37 17 32962033 32962033 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 15 94 0 ENST00000321639.5:c.1634G>A p.Gly545Asp p.G545D ENST00000321639 NM_207313.1 545 gGc/gAc 0 +TMEM132E UCSF GRCh37 17 32965084 32965084 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 5 38 0 ENST00000321639.5:c.2788A>G p.Thr930Ala p.T930A ENST00000321639 NM_207313.1 930 Acg/Gcg 0 +TMEM169 UCSF GRCh37 2 216960818 216960818 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 5 55 0 ENST00000295658.4:c.132G>A p.Arg44= p.R44= ENST00000295658 NM_001142311.1 44 agG/agA 0 +TMEM181 UCSF GRCh37 6 158957817 158957817 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 8 54 0 ENST00000367090.3:c.339G>A p.Lys113= p.K113= ENST00000367090 NM_020823.1 113 aaG/aaA 0 +TMEM201 UCSF GRCh37 1 9661372 9661372 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 234 48 260 0 ENST00000340381.6:c.816G>A p.Arg272= p.R272= ENST00000340381 NM_001130924.2 272 cgG/cgA 0 +TMEM222 UCSF GRCh37 1 27660449 27660449 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 15 116 0 ENST00000374076.4:c.312G>A p.Lys104= p.K104= ENST00000374076 NM_032125.2 104 aaG/aaA 0 +TMEM25 UCSF GRCh37 11 118403728 118403728 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 157 21 165 0 ENST00000313236.5:c.479C>T p.Pro160Leu p.P160L ENST00000313236 NM_032780.3 160 cCg/cTg 0 +TMEM42 UCSF GRCh37 3 44903518 44903518 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 37 0 ENST00000302392.4:c.102G>A p.Arg34= p.R34= ENST00000302392 NM_144638.1 34 cgG/cgA 0 +TMEM53 UCSF GRCh37 1 45120392 45120392 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 12 106 0 ENST00000372237.3:c.673G>A p.Ala225Thr p.A225T ENST00000372237 NM_024587.2 225 Gcc/Acc 0 +TMEM55B UCSF GRCh37 14 20927400 20927400 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 20 71 0 ENST00000250489.4:c.655G>C p.Gly219Arg p.G219R ENST00000250489 219 Ggc/Cgc 0 +TMEM59 UCSF GRCh37 1 54518683 54518683 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 15 76 0 ENST00000234831.5:c.179C>T p.Thr60Ile p.T60I ENST00000234831 NM_004872.3 60 aCc/aTc 0 +TMEM62 UCSF GRCh37 15 43470893 43470893 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 10 141 0 ENST00000260403.2:c.1470C>T p.Thr490= p.T490= ENST00000260403 NM_024956.3 490 acC/acT 0 +TMEM8A UCSF GRCh37 16 427491 427491 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 20 95 0 ENST00000431232.2:c.394C>T p.Pro132Ser p.P132S ENST00000431232 NM_021259.2 132 Ccg/Tcg 0 +TMPRSS11A UCSF GRCh37 4 68788560 68788560 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 21 151 0 ENST00000334830.7:c.614C>T p.Ala205Val p.A205V ENST00000334830 205 gCt/gTt 0 +TMPRSS3 UCSF GRCh37 21 43808636 43808636 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 13 92 0 ENST00000291532.3:c.323-1G>A p.X108_splice ENST00000291532 NM_032404.2 0 +TMPRSS9 UCSF GRCh37 19 2415743 2415743 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 15 96 0 ENST00000332578.3:c.1547C>T p.Pro516Leu p.P516L ENST00000332578 NM_182973.1 516 cCc/cTc 0 +TMTC2 UCSF GRCh37 12 83251288 83251288 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 16 119 0 ENST00000321196.3:c.583G>A p.Val195Ile p.V195I ENST00000321196 NM_152588.1 195 Gtt/Att 0 +TNC UCSF GRCh37 9 117822222 117822222 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 15 154 0 ENST00000350763.4:c.4093C>T p.Leu1365Phe p.L1365F ENST00000350763 NM_002160.3 1365 Ctc/Ttc 0 +TNC UCSF GRCh37 9 117797614 117797614 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 72 0 ENST00000350763.4:c.5657-1G>A p.X1886_splice ENST00000350763 NM_002160.3 0 +TNFAIP3 UCSF GRCh37 6 138196016 138196016 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 19 70 0 ENST00000237289.4:c.330G>A p.Gln110= p.Q110= ENST00000237289 NM_001270507.1 110 caG/caA 0 +TNFRSF12A UCSF GRCh37 16 3071622 3071622 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 9 103 0 ENST00000326577.4:c.266C>T p.Thr89Ile p.T89I ENST00000326577 NM_016639.2 89 aCc/aTc 0 +TNFRSF12A UCSF GRCh37 16 3071303 3071303 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 30 0 ENST00000326577.4:c.182G>A p.Ser61Asn p.S61N ENST00000326577 NM_016639.2 61 aGc/aAc 0 +TNFRSF4 UCSF GRCh37 1 1149139 1149139 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 5 59 0 ENST00000379236.3:c.172C>T p.Arg58Cys p.R58C ENST00000379236 NM_003327.3 58 Cgc/Tgc 0 +TNN UCSF GRCh37 1 175063312 175063312 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 8 88 0 ENST00000239462.4:c.1511G>A p.Gly504Glu p.G504E ENST00000239462 NM_022093.1 504 gGa/gAa 0 +TNNI3 UCSF GRCh37 19 55666175 55666175 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 426 74 506 0 ENST00000344887.5:c.306C>T p.Ala102= p.A102= ENST00000344887 NM_000363.4 102 gcC/gcT 0 +TNR UCSF GRCh37 1 175304879 175304879 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 43 181 0 ENST00000263525.2:c.3599G>A p.Gly1200Asp p.G1200D ENST00000263525 NM_003285.2 1200 gGc/gAc 0 +TNRC6A UCSF GRCh37 16 24802848 24802848 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 19 216 0 ENST00000395799.3:c.2885C>T p.Thr962Ile p.T962I ENST00000395799 NM_014494.2 962 aCa/aTa 0 +TNRC6A UCSF GRCh37 16 24802814 24802814 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 33 236 0 ENST00000395799.3:c.2851G>A p.Asp951Asn p.D951N ENST00000395799 NM_014494.2 951 Gac/Aac 0 +TNRC6B UCSF GRCh37 22 40708906 40708906 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 35 272 0 ENST00000454349.2:c.4583G>A p.Gly1528Glu p.G1528E ENST00000454349 NM_001162501.1 1528 gGg/gAg 0 +TNS1 UCSF GRCh37 2 218682831 218682831 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 47 116 0 ENST00000171887.4:c.3912C>T p.Leu1304= p.L1304= ENST00000171887 NM_022648.4 1304 ctC/ctT 0 +TOM1 UCSF GRCh37 22 35713910 35713910 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 29 249 1 ENST00000449058.2:c.93C>T p.Ala31= p.A31= ENST00000449058 NM_005488.2 31 gcC/gcT 0 +TOM1L2 UCSF GRCh37 17 17810816 17810816 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 8 52 0 ENST00000379504.3:c.82G>A p.Glu28Lys p.E28K ENST00000379504 NM_001082968.1 28 Gag/Aag 0 +TOMM20L UCSF GRCh37 14 58862680 58862680 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 7 68 0 ENST00000360945.2:c.5C>T p.Pro2Leu p.P2L ENST00000360945 NM_207377.2 2 cCc/cTc 0 +TOP3B UCSF GRCh37 22 22323107 22323107 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 13 133 0 ENST00000357179.5:c.622G>A p.Asp208Asn p.D208N ENST00000357179 NM_001282113.1 208 Gac/Aac 0 +TOPBP1 UCSF GRCh37 3 133376764 133376764 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 5 47 0 ENST00000260810.5:c.241C>T p.Pro81Ser p.P81S ENST00000260810 NM_007027.3 81 Cct/Tct 0 +TOR1A UCSF GRCh37 9 132584870 132584870 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 38 267 0 ENST00000351698.4:c.434C>T p.Thr145Ile p.T145I ENST00000351698 NM_000113.2 145 aCc/aTc 0 +TOR1B UCSF GRCh37 9 132571844 132571844 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 18 172 0 ENST00000259339.2:c.993G>A p.Ser331= p.S331= ENST00000259339 NM_014506.1 331 tcG/tcA 0 +TOX2 UCSF GRCh37 20 42694411 42694411 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 30 209 0 ENST00000358131.5:c.966C>T p.Leu322= p.L322= ENST00000358131 NM_001098798.1 322 ctC/ctT 0 +TP53 UCSF GRCh37 17 7576858 7576858 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 0 ENST00000269305.4:c.988delC p.Leu330PhefsTer15 p.L330Ffs*15 ENST00000269305 NM_001126112.2 330 Ctt/tt 0 +TP53I11 UCSF GRCh37 11 44958415 44958415 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 8 28 0 ENST00000308212.5:c.273C>T p.Val91= p.V91= ENST00000308212 NM_001258321.1 91 gtC/gtT 0 +TP73 UCSF GRCh37 1 3599662 3599662 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 25 154 0 ENST00000378295.4:c.104G>A p.Ser35Asn p.S35N ENST00000378295 NM_005427.3 35 aGc/aAc 0 +TPP2 UCSF GRCh37 13 103326689 103326689 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 4 36 0 ENST00000376065.4:c.3389C>T p.Ala1130Val p.A1130V ENST00000376065 NM_003291.2 1130 gCc/gTc 0 +TRADD UCSF GRCh37 16 67188669 67188669 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 25 194 0 ENST00000345057.4:c.822G>A p.Gln274= p.Q274= ENST00000345057 NM_003789.3 274 caG/caA 0 +TRAK2 UCSF GRCh37 2 202260088 202260088 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 199 37 268 0 ENST00000332624.3:c.849G>A p.Glu283= p.E283= ENST00000332624 NM_015049.2 283 gaG/gaA 0 +TRAM2 UCSF GRCh37 6 52370449 52370449 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 68 175 0 ENST00000182527.3:c.823G>A p.Glu275Lys p.E275K ENST00000182527 NM_012288.3 275 Gaa/Aaa 0 +TRAPPC10 UCSF GRCh37 21 45514041 45514041 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 14 125 0 ENST00000291574.4:c.3095C>T p.Ser1032Phe p.S1032F ENST00000291574 NM_003274.4 1032 tCc/tTc 0 +TRAPPC8 UCSF GRCh37 18 29522635 29522635 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 13 87 0 ENST00000283351.4:c.93C>T p.Leu31= p.L31= ENST00000283351 NM_014939.3 31 ctC/ctT 0 +TRIM29 UCSF GRCh37 11 120008482 120008482 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 23 196 0 ENST00000341846.5:c.258G>A p.Gly86= p.G86= ENST00000341846 NM_012101.3 86 ggG/ggA 0 +TRIM38 UCSF GRCh37 6 25972150 25972150 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 16 162 0 ENST00000357085.3:c.561G>A p.Gln187= p.Q187= ENST00000357085 NM_006355.3 187 caG/caA 0 +TRIM46 UCSF GRCh37 1 155156634 155156634 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 221 37 301 0 ENST00000334634.4:c.2248G>A p.Val750Ile p.V750I ENST00000334634 NM_001282378.1 750 Gtc/Atc 0 +TRIM59 UCSF GRCh37 3 160156831 160156831 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 19 171 0 ENST00000309784.4:c.141G>A p.Trp47Ter p.W47* ENST00000309784 NM_173084.2 47 tgG/tgA 0 +TRIM6 UCSF GRCh37 11 5624670 5624670 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 43 178 0 ENST00000278302.5:c.128G>A p.Gly43Asp p.G43D ENST00000278302 NM_058166.4 43 gGc/gAc 0 +TRIM6 UCSF GRCh37 11 5631473 5631473 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 14 128 0 ENST00000278302.5:c.872G>A p.Arg291Lys p.R291K ENST00000278302 NM_058166.4 291 aGa/aAa 0 +TRIM69 UCSF GRCh37 15 45051860 45051860 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 12 145 0 ENST00000329464.4:c.836G>A p.Ser279Asn p.S279N ENST00000329464 NM_182985.3 279 aGc/aAc 0 +TRIM8 UCSF GRCh37 10 104416075 104416075 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 20 163 0 ENST00000302424.7:c.981C>T p.His327= p.H327= ENST00000302424 NM_030912.2 327 caC/caT 0 +TRIOBP UCSF GRCh37 22 38121147 38121147 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 378 62 565 1 ENST00000406386.3:c.2584G>A p.Asp862Asn p.D862N ENST00000406386 NM_001039141.2 862 Gac/Aac 0 +TRIP11 UCSF GRCh37 14 92505980 92505980 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 4 46 0 ENST00000267622.4:c.50G>A p.Gly17Asp p.G17D ENST00000267622 NM_004239.3 17 gGt/gAt 0 +TRMT11 UCSF GRCh37 6 126329619 126329619 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 25 200 0 ENST00000334379.5:c.760+1G>A p.X254_splice ENST00000334379 NM_001031712.2 0 +TRO UCSF GRCh37 X 54949066 54949066 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 15 135 0 ENST00000173898.7:c.101C>T p.Thr34Ile p.T34I ENST00000173898 NM_001039705.2 34 aCt/aTt 0 +TRPC4 UCSF GRCh37 13 38211153 38211153 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 41 380 0 ENST00000379705.3:c.2821G>A p.Val941Ile p.V941I ENST00000379705 941 Gtt/Att 0 +TRPM1 UCSF GRCh37 15 31330285 31330285 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 20 123 0 ENST00000397795.2:c.2335G>A p.Glu779Lys p.E779K ENST00000397795 NM_002420.5 779 Gaa/Aaa 0 +TRPM8 UCSF GRCh37 2 234888831 234888831 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 53 0 ENST00000324695.4:c.2356-1G>A p.X786_splice ENST00000324695 NM_024080.4 0 +TRPM8 UCSF GRCh37 2 234851359 234851359 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 10 83 0 ENST00000324695.4:c.666C>T p.Asn222= p.N222= ENST00000324695 NM_024080.4 222 aaC/aaT 0 +TRPM8 UCSF GRCh37 2 234863816 234863816 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 27 345 0 ENST00000324695.4:c.1284G>A p.Gly428= p.G428= ENST00000324695 NM_024080.4 428 ggG/ggA 0 +TRPV2 UCSF GRCh37 17 16321100 16321100 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 8 96 0 ENST00000338560.7:c.118G>A p.Glu40Lys p.E40K ENST00000338560 NM_016113.4 40 Gag/Aag 0 +TRPV4 UCSF GRCh37 12 110222122 110222122 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 6 79 0 ENST00000261740.2:c.2457G>A p.Arg819= p.R819= ENST00000261740 NM_021625.4 819 agG/agA 0 +TRUB2 UCSF GRCh37 9 131077889 131077889 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 21 198 0 ENST00000372890.4:c.335G>A p.Gly112Glu p.G112E ENST00000372890 NM_015679.1 112 gGa/gAa 0 +TSGA14 UCSF GRCh37 7 130041759 130041759 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 28 207 0 ENST00000223208.5:c.605G>A p.Arg202Lys p.R202K ENST00000223208 NM_018718.2 202 aGa/aAa 0 +TSNAXIP1 UCSF GRCh37 16 67855009 67855009 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 18 129 0 ENST00000388833.3:c.106C>T p.Gln36Ter p.Q36* ENST00000388833 NM_018430.2 36 Cag/Tag 0 +TSPYL2 UCSF GRCh37 X 53112164 53112164 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 17 67 0 ENST00000375442.4:c.484C>T p.Pro162Ser p.P162S ENST00000375442 NM_022117.3 162 Ccg/Tcg 0 +TSTD2 UCSF GRCh37 9 100367915 100367915 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 71 0 ENST00000341170.4:c.963C>T p.Phe321= p.F321= ENST00000341170 NM_139246.4 321 ttC/ttT 0 +TTBK1 UCSF GRCh37 6 43221096 43221096 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 11 80 1 ENST00000259750.4:c.324G>A p.Gln108= p.Q108= ENST00000259750 NM_032538.1 108 caG/caA 0 +TTC16 UCSF GRCh37 9 130491936 130491936 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 14 135 0 ENST00000373289.3:c.1841C>T p.Ser614Phe p.S614F ENST00000373289 NM_144965.1 614 tCc/tTc 0 +TTC17 UCSF GRCh37 11 43422997 43422997 + frameshift_variant,splice_region_variant Frame_Shift_Del DEL A A - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 0 ENST00000039989.4:c.1223del p.Asn408IlefsTer47 p.N408Ifs*47 ENST00000039989 NM_018259.5 407 ggA/gg 0 +TTC24 UCSF GRCh37 1 156551840 156551840 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 13 83 0 ENST00000368236.3:c.684G>A p.Arg228= p.R228= ENST00000368236 NM_001105669.2 228 agG/agA 0 +TTC28 UCSF GRCh37 22 28693690 28693690 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 9 87 0 ENST00000397906.2:c.680C>T p.Thr227Ile p.T227I ENST00000397906 NM_001145418.1 227 aCc/aTc 0 +TTC3 UCSF GRCh37 21 38466339 38466339 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 14 116 0 ENST00000354749.2:c.636C>T p.Asp212= p.D212= ENST00000354749 212 gaC/gaT 0 +TTC5 UCSF GRCh37 14 20764555 20764555 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 61 0 ENST00000258821.3:c.690G>A p.Arg230= p.R230= ENST00000258821 NM_138376.2 230 agG/agA 0 +TTC8 UCSF GRCh37 14 89336424 89336424 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 27 296 0 ENST00000380656.2:c.931G>A p.Ala311Thr p.A311T ENST00000380656 NM_144596.2 311 Gca/Aca 0 +TTF2 UCSF GRCh37 1 117624491 117624491 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 39 162 0 ENST00000369466.4:c.1825C>G p.Leu609Val p.L609V ENST00000369466 NM_003594.3 609 Ctc/Gtc 0 +TTLL10 UCSF GRCh37 1 1116199 1116199 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 3 36 0 ENST00000379289.1:c.714C>T p.Ala238= p.A238= ENST00000379289 NM_001130045.1 238 gcC/gcT 0 +TTN UCSF GRCh37 2 179422822 179422822 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 10 145 0 ENST00000591111.1:c.82336G>A p.Ala27446Thr p.A27446T ENST00000591111 27446 Gca/Aca 0 +TTN UCSF GRCh37 2 179485448 179485448 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 256 43 428 0 ENST00000591111.1:c.40966G>A p.Val13656Ile p.V13656I ENST00000591111 13656 Gta/Ata 0 +TTN UCSF GRCh37 2 179633595 179633595 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 30 317 0 ENST00000591111.1:c.8968G>A p.Val2990Met p.V2990M ENST00000591111 2990 Gtg/Atg 0 +TTN UCSF GRCh37 2 179417827 179417827 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 12 146 0 ENST00000591111.1:c.84877C>T p.Pro28293Ser p.P28293S ENST00000591111 28293 Cca/Tca 0 +TTN UCSF GRCh37 2 179587979 179587979 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 180 23 276 0 ENST00000591111.1:c.20804C>T p.Thr6935Ile p.T6935I ENST00000591111 6935 aCc/aTc 0 +TTN UCSF GRCh37 2 179401238 179401238 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 13 132 0 ENST00000591111.1:c.95313C>T p.Ala31771= p.A31771= ENST00000591111 31771 gcC/gcT 0 +TUBA3C UCSF GRCh37 13 19748285 19748285 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 29 0 ENST00000400113.3:c.1071C>T p.Tyr357= p.Y357= ENST00000400113 NM_006001.2 357 taC/taT 0 +TUBGCP5 UCSF GRCh37 15 22855156 22855156 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 6 26 0 ENST00000283645.4:c.1617G>A p.Gln539= p.Q539= ENST00000283645 NM_052903.4 539 caG/caA 0 +TUFM UCSF GRCh37 16 28855093 28855093 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 4 13 0 ENST00000313511.3:c.1158G>A p.Trp386Ter p.W386* ENST00000313511 NM_003321.4 386 tgG/tgA 0 +TXLNB UCSF GRCh37 6 139591620 139591620 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 13 118 0 ENST00000358430.3:c.660G>A p.Glu220= p.E220= ENST00000358430 NM_153235.3 220 gaG/gaA 0 +TXNDC11 UCSF GRCh37 16 11773604 11773604 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 20 201 1 ENST00000356957.3:c.2405C>T p.Ser802Phe p.S802F ENST00000356957 802 tCc/tTc 0 +TXNL1 UCSF GRCh37 18 54281696 54281696 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 22 235 0 ENST00000217515.6:c.694C>T p.Pro232Ser p.P232S ENST00000217515 NM_004786.2 232 Cca/Tca 0 +TYW3 UCSF GRCh37 1 75229704 75229704 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 250 49 388 0 ENST00000370867.3:c.687C>T p.Ala229= p.A229= ENST00000370867 NM_138467.2 229 gcC/gcT 0 +UACA UCSF GRCh37 15 70975129 70975129 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 5 104 0 ENST00000322954.6:c.790G>A p.Glu264Lys p.E264K ENST00000322954 NM_018003.2 264 Gaa/Aaa 0 +UBA1 UCSF GRCh37 X 47074325 47074325 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 32 112 0 ENST00000335972.6:c.3174C>T p.Arg1058= p.R1058= ENST00000335972 NM_003334.3 1058 cgC/cgT 0 +UBA7 UCSF GRCh37 3 49846990 49846990 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 275 44 379 0 ENST00000333486.3:c.2073C>T p.His691= p.H691= ENST00000333486 NM_003335.2 691 caC/caT 0 +UBE2E2 UCSF GRCh37 3 23631264 23631264 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 24 215 0 ENST00000396703.1:c.548C>T p.Thr183Ile p.T183I ENST00000396703 NM_152653.3 183 aCc/aTc 0 +UBE2E2 UCSF GRCh37 3 23250183 23250183 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 36 113 0 ENST00000396703.1:c.-8G>A p.X3_splice ENST00000396703 NM_152653.3 0 +UBE2G2 UCSF GRCh37 21 46197237 46197237 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 48 182 0 ENST00000345496.2:c.221C>T p.Thr74Ile p.T74I ENST00000345496 NM_003343.5 74 aCc/aTc 0 +UBE2Q1 UCSF GRCh37 1 154525615 154525615 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 15 151 0 ENST00000292211.4:c.622G>A p.Glu208Lys p.E208K ENST00000292211 NM_017582.6 208 Gag/Aag 0 +UBE2U UCSF GRCh37 1 64680588 64680588 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 9 70 0 ENST00000371076.3:c.430C>T p.Leu144= p.L144= ENST00000371076 NM_152489.1 144 Cta/Tta 0 +UBE4B UCSF GRCh37 1 10211519 10211519 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 34 297 0 ENST00000343090.6:c.2826C>T p.Asn942= p.N942= ENST00000343090 NM_001105562.2 942 aaC/aaT 0 +UBL4A UCSF GRCh37 X 153713937 153713937 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 12 75 0 ENST00000369660.4:c.415G>A p.Ala139Thr p.A139T ENST00000369660 NM_014235.3 139 Gcc/Acc 0 +UBN1 UCSF GRCh37 16 4926992 4926992 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 25 151 0 ENST00000262376.6:c.3145G>A p.Val1049Ile p.V1049I ENST00000262376 NM_001079514.1 1049 Gtc/Atc 0 +UBQLN2 UCSF GRCh37 X 56590846 56590846 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 19 58 0 ENST00000338222.5:c.540G>A p.Glu180= p.E180= ENST00000338222 NM_013444.3 180 gaG/gaA 0 +UBR1 UCSF GRCh37 15 43360098 43360098 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 11 35 0 ENST00000290650.4:c.796G>A p.Glu266Lys p.E266K ENST00000290650 NM_174916.2 266 Gag/Aag 0 +UBR1 UCSF GRCh37 15 43317174 43317174 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 14 156 0 ENST00000290650.4:c.2592G>A p.Pro864= p.P864= ENST00000290650 NM_174916.2 864 ccG/ccA 0 +UBR1 UCSF GRCh37 15 43346981 43346981 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 238 33 309 0 ENST00000290650.4:c.1398G>A p.Gln466= p.Q466= ENST00000290650 NM_174916.2 466 caG/caA 0 +UBR3 UCSF GRCh37 2 170917685 170917685 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 25 364 0 ENST00000272793.5:c.4882G>A p.Glu1628Lys p.E1628K ENST00000272793 1628 Gaa/Aaa 0 +UBR4 UCSF GRCh37 1 19525077 19525077 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 10 118 0 ENST00000375254.3:c.606C>T p.Asn202= p.N202= ENST00000375254 NM_020765.2 202 aaC/aaT 0 +UBR5 UCSF GRCh37 8 103317361 103317361 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 21 171 0 ENST00000520539.1:c.2779G>A p.Val927Ile p.V927I ENST00000520539 NM_015902.5 927 Gta/Ata 0 +UBR5 UCSF GRCh37 8 103266681 103266681 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 17 138 0 ENST00000520539.1:c.8249C>T p.Pro2750Leu p.P2750L ENST00000520539 NM_015902.5 2750 cCc/cTc 0 +UCK2 UCSF GRCh37 1 165859506 165859506 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 7 72 0 ENST00000367879.4:c.165G>A p.Gln55= p.Q55= ENST00000367879 NM_012474.4 55 caG/caA 0 +UCN3 UCSF GRCh37 10 5416100 5416100 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 407 73 227 0 ENST00000380433.3:c.417G>A p.Lys139= p.K139= ENST00000380433 NM_053049.2 139 aaG/aaA 0 +UFSP2 UCSF GRCh37 4 186329183 186329183 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 12 143 0 ENST00000264689.6:c.1028C>T p.Thr343Ile p.T343I ENST00000264689 NM_018359.3 343 aCa/aTa 0 +UGDH UCSF GRCh37 4 39512330 39512330 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 298 35 408 0 ENST00000316423.6:c.416G>A p.Ser139Asn p.S139N ENST00000316423 NM_001184701.1 139 aGt/aAt 0 +UGT2B10 UCSF GRCh37 4 69885857 69885857 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 26 205 0 ENST00000505092.1:n.276G>A *92* ENST00000505092 0 +UGT2B11 UCSF GRCh37 4 70080370 70080370 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 7 64 0 ENST00000446444.1:c.71G>A p.Gly24Glu p.G24E ENST00000446444 NM_001073.1 24 gGa/gAa 0 +UHRF1BP1 UCSF GRCh37 6 34827090 34827090 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 22 175 0 ENST00000192788.5:c.2957C>T p.Ser986Phe p.S986F ENST00000192788 NM_017754.3 986 tCc/tTc 0 +ULK1 UCSF GRCh37 12 132379581 132379581 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 7 45 0 ENST00000321867.4:c.35G>A p.Gly12Asp p.G12D ENST00000321867 NM_003565.2 12 gGc/gAc 0 +ULK2 UCSF GRCh37 17 19741882 19741882 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 17 170 0 ENST00000361658.2:c.719C>T p.Thr240Ile p.T240I ENST00000361658 NM_001142610.1 240 aCa/aTa 0 +ULK3 UCSF GRCh37 15 75131027 75131027 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 24 189 0 ENST00000440863.2:c.1059G>A p.Gln353= p.Q353= ENST00000440863 NM_001099436.1 353 caG/caA 0 +UMOD UCSF GRCh37 16 20360023 20360023 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 8 45 0 ENST00000302509.4:c.600C>T p.Arg200= p.R200= ENST00000302509 200 cgC/cgT 0 +UMODL1 UCSF GRCh37 21 43533867 43533867 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 11 103 0 ENST00000408910.2:c.2289C>T p.Val763= p.V763= ENST00000408910 NM_001004416.2 763 gtC/gtT 0 +UNC13B UCSF GRCh37 9 35396476 35396476 + missense_variant Missense_Mutation SNP A A G snp132_rs17849220 P24_Rec2 Untested WXS Illumina HiSeq 179 37 413 0 ENST00000378495.3:c.3065A>G p.His1022Arg p.H1022R ENST00000378495 NM_006377.3 1022 cAt/cGt 0 +UNC13B UCSF GRCh37 9 35313986 35313986 + missense_variant,splice_region_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 7 94 0 ENST00000378495.3:c.1167G>T p.Glu389Asp p.E389D ENST00000378495 NM_006377.3 389 gaG/gaT 0 +UNC13D UCSF GRCh37 17 73839293 73839293 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 11 56 0 ENST00000207549.4:c.208C>T p.Pro70Ser p.P70S ENST00000207549 NM_199242.2 70 Cct/Tct 0 +UNC5C UCSF GRCh37 4 96123949 96123949 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 19 57 0 ENST00000453304.1:c.2069T>A p.Leu690Gln p.L690Q ENST00000453304 NM_003728.3 690 cTg/cAg 0 +UNC5C UCSF GRCh37 4 96166234 96166234 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 18 206 0 ENST00000453304.1:c.837G>A p.Gly279= p.G279= ENST00000453304 NM_003728.3 279 ggG/ggA 0 +UNC5D UCSF GRCh37 8 35648074 35648074 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 20 183 0 ENST00000404895.2:c.2855G>A p.Gly952Glu p.G952E ENST00000404895 NM_080872.2 952 gGa/gAa 0 +UNC79 UCSF GRCh37 14 94107551 94107551 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 21 210 0 ENST00000393151.2:c.5978C>T p.Pro1993Leu p.P1993L ENST00000393151 1993 cCt/cTt 0 +UNC79 UCSF GRCh37 14 94038423 94038423 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 5 68 0 ENST00000393151.2:c.1939G>A p.Val647Ile p.V647I ENST00000393151 647 Gta/Ata 0 +UNC80 UCSF GRCh37 2 210841652 210841652 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 6 54 0 ENST00000439458.1:c.8590G>A p.Ala2864Thr p.A2864T ENST00000439458 NM_032504.1 2864 Gca/Aca 0 +UNC80 UCSF GRCh37 2 210642283 210642283 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 14 109 0 ENST00000439458.1:c.600G>A p.Lys200= p.K200= ENST00000439458 NM_032504.1 200 aaG/aaA 0 +UPF3B UCSF GRCh37 X 118968844 118968844 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 47 238 0 ENST00000276201.2:c.1449G>A p.Glu483= p.E483= ENST00000276201 NM_080632.2 483 gaG/gaA 0 +UPK3B UCSF GRCh37 7 76142480 76142480 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 20 152 0 ENST00000257632.5:c.627-784G>A *209* ENST00000257632 0 +URB1 UCSF GRCh37 21 33691589 33691589 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 15 166 0 ENST00000382751.3:c.5730G>A p.Arg1910= p.R1910= ENST00000382751 NM_014825.2 1910 cgG/cgA 0 +UROD UCSF GRCh37 1 45478816 45478816 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 13 101 0 ENST00000246337.4:c.142G>A p.Glu48Lys p.E48K ENST00000246337 NM_000374.4 48 Gaa/Aaa 0 +USF1 UCSF GRCh37 1 161010078 161010078 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 19 164 0 ENST00000368020.1:c.757G>A p.Glu253Lys p.E253K ENST00000368020 NM_001276373.1 253 Gag/Aag 0 +USH2A UCSF GRCh37 1 216243514 216243514 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 65 260 0 ENST00000307340.3:c.5978G>A p.Ser1993Asn p.S1993N ENST00000307340 NM_206933.2 1993 aGt/aAt 0 +USH2A UCSF GRCh37 1 216373016 216373016 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 28 97 0 ENST00000307340.3:c.3764G>A p.Ser1255Asn p.S1255N ENST00000307340 NM_206933.2 1255 aGt/aAt 0 +USP24 UCSF GRCh37 1 55603253 55603253 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 18 131 0 ENST00000294383.6:c.3136G>A p.Asp1046Asn p.D1046N ENST00000294383 NM_015306.2 1046 Gat/Aat 0 +USP26 UCSF GRCh37 X 132159747 132159747 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 29 202 0 ENST00000370832.1:c.2502G>A p.Gly834= p.G834= ENST00000370832 NM_031907.1 834 ggG/ggA 0 +USP35 UCSF GRCh37 11 77921284 77921284 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 26 209 0 ENST00000529308.1:c.2383G>A p.Val795Met p.V795M ENST00000529308 NM_020798.2 795 Gtg/Atg 0 +USP36 UCSF GRCh37 17 76832208 76832208 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 7 49 0 ENST00000542802.3:c.238C>T p.Pro80Ser p.P80S ENST00000542802 80 Ccg/Tcg 0 +USP37 UCSF GRCh37 2 219324517 219324517 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 49 235 0 ENST00000258399.3:c.2639C>T p.Ala880Val p.A880V ENST00000258399 NM_020935.2 880 gCt/gTt 0 +USP38 UCSF GRCh37 4 144136024 144136024 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 72 250 0 ENST00000307017.4:c.2895G>A p.Trp965Ter p.W965* ENST00000307017 NM_032557.5 965 tgG/tgA 0 +USP42 UCSF GRCh37 7 6187440 6187440 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 20 169 0 ENST00000306177.5:c.1303C>T p.Pro435Ser p.P435S ENST00000306177 NM_032172.2 435 Ccc/Tcc 0 +USP43 UCSF GRCh37 17 9603504 9603504 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 13 94 0 ENST00000285199.7:c.1473G>A p.Arg491= p.R491= ENST00000285199 NM_001267576.1 491 agG/agA 0 +USP43 UCSF GRCh37 17 9631785 9631785 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 16 162 0 ENST00000285199.7:c.2850G>A p.Gln950= p.Q950= ENST00000285199 NM_001267576.1 950 caG/caA 0 +USP49 UCSF GRCh37 6 41774193 41774193 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 45 0 ENST00000373009.3:c.529G>A p.Ala177Thr p.A177T ENST00000373009 177 Gcc/Acc 0 +USP54 UCSF GRCh37 10 75289484 75289484 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 31 290 0 ENST00000339859.4:c.2014C>T p.Pro672Ser p.P672S ENST00000339859 672 Cct/Tct 0 +USP54 UCSF GRCh37 10 75276770 75276770 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 6 113 0 ENST00000339859.4:c.3414G>A p.Arg1138= p.R1138= ENST00000339859 1138 agG/agA 0 +USP54 UCSF GRCh37 10 75279635 75279635 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 3 43 0 ENST00000339859.4:c.2598G>A p.Gln866= p.Q866= ENST00000339859 866 caG/caA 0 +UTP20 UCSF GRCh37 12 101755786 101755786 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 41 114 0 ENST00000261637.4:c.5738C>T p.Thr1913Ile p.T1913I ENST00000261637 NM_014503.2 1913 aCc/aTc 0 +UTP20 UCSF GRCh37 12 101728261 101728261 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 9 46 0 ENST00000261637.4:c.3620G>A p.Ser1207Asn p.S1207N ENST00000261637 NM_014503.2 1207 aGt/aAt 0 +UTP20 UCSF GRCh37 12 101763522 101763522 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 9 99 0 ENST00000261637.4:c.6408C>T p.Cys2136= p.C2136= ENST00000261637 NM_014503.2 2136 tgC/tgT 0 +UTY UCSF GRCh37 Y 15409660 15409660 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 11 75 0 ENST00000331397.4:c.3646C>T p.Pro1216Ser p.P1216S ENST00000331397 NM_001258267.1 1216 Ccc/Tcc 0 +UVRAG UCSF GRCh37 11 75851986 75851986 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 50 186 0 ENST00000356136.3:c.1629G>A p.Lys543= p.K543= ENST00000356136 NM_003369.3 543 aaG/aaA 0 +VAC14 UCSF GRCh37 16 70796792 70796792 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 13 140 0 ENST00000261776.5:c.1297C>T p.Pro433Ser p.P433S ENST00000261776 NM_018052.3 433 Cct/Tct 0 +VARS UCSF GRCh37 6 31748671 31748671 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 16 176 0 ENST00000375663.3:c.2694G>A p.Glu898= p.E898= ENST00000375663 NM_006295.2 898 gaG/gaA 0 +VCAN UCSF GRCh37 5 82835603 82835603 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 243 41 378 0 ENST00000265077.3:c.6781G>A p.Glu2261Lys p.E2261K ENST00000265077 NM_004385.4 2261 Gaa/Aaa 0 +VDAC1 UCSF GRCh37 5 133309511 133309511 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 22 246 0 ENST00000265333.3:c.731G>A p.Gly244Asp p.G244D ENST00000265333 NM_003374.2 244 gGt/gAt 0 +VENTX UCSF GRCh37 10 135053573 135053573 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 34 292 0 ENST00000325980.9:c.540G>A p.Leu180= p.L180= ENST00000325980 NM_014468.3 180 ctG/ctA 0 +VEPH1 UCSF GRCh37 3 157034872 157034872 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 17 174 0 ENST00000362010.2:c.1854G>A p.Gln618= p.Q618= ENST00000362010 NM_001167912.1 618 caG/caA 0 +VGLL1 UCSF GRCh37 X 135630884 135630884 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 140 207 0 ENST00000370634.3:c.351G>A p.Pro117= p.P117= ENST00000370634 NM_016267.3 117 ccG/ccA 0 +VIL1 UCSF GRCh37 2 219301264 219301264 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 25 179 0 ENST00000248444.5:c.1886G>A p.Gly629Glu p.G629E ENST00000248444 NM_007127.2 629 gGg/gAg 0 +VMO1 UCSF GRCh37 17 4689332 4689332 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 219 38 292 0 ENST00000328739.5:c.211G>A p.Gly71Ser p.G71S ENST00000328739 NM_182566.2 71 Ggc/Agc 0 +VPRBP UCSF GRCh37 3 51475506 51475506 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 221 45 365 0 ENST00000504652.1:c.921G>A p.Met307Ile p.M307I ENST00000504652 307 atG/atA 0 +VPRBP UCSF GRCh37 3 51440740 51440740 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 373 79 565 0 ENST00000423656.1:c.3015G>A p.Glu1005= p.E1005= ENST00000423656 1005 gaG/gaA 0 +VPS13A UCSF GRCh37 9 79959108 79959108 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 12 200 0 ENST00000360280.3:c.7066C>T p.Leu2356Phe p.L2356F ENST00000360280 NM_033305.2 2356 Ctt/Ttt 0 +VPS13B UCSF GRCh37 8 100887766 100887766 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 21 214 0 ENST00000358544.2:c.11941G>A p.Val3981Met p.V3981M ENST00000358544 NM_017890.4 3981 Gtg/Atg 0 +VPS13C UCSF GRCh37 15 62237972 62237972 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 242 41 347 0 ENST00000261517.5:c.5090G>A p.Ser1697Asn p.S1697N ENST00000261517 NM_020821.2 1697 aGt/aAt 0 +VPS13D UCSF GRCh37 1 12327930 12327930 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 8 65 0 ENST00000358136.3:c.1754C>T p.Ser585Phe p.S585F ENST00000358136 NM_015378.2 585 tCt/tTt 0 +VPS13D UCSF GRCh37 1 12364765 12364765 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 8 74 0 ENST00000358136.3:c.6419G>A p.Gly2140Asp p.G2140D ENST00000358136 NM_015378.2 2140 gGc/gAc 0 +VPS39 UCSF GRCh37 15 42453941 42453941 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 16 211 0 ENST00000348544.4:c.2524G>A p.Val842Met p.V842M ENST00000348544 842 Gtg/Atg 0 +VPS45 UCSF GRCh37 1 150064042 150064042 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 14 106 0 ENST00000369130.3:c.1116G>A p.Arg372= p.R372= ENST00000369130 NM_001279354.1 372 agG/agA 0 +VPS4B UCSF GRCh37 18 61064452 61064452 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 20 303 0 ENST00000238497.5:c.907C>T p.Pro303Ser p.P303S ENST00000238497 NM_004869.3 303 Ccc/Tcc 0 +VSIG8 UCSF GRCh37 1 159828607 159828607 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 11 72 0 ENST00000368100.1:c.145G>A p.Asp49Asn p.D49N ENST00000368100 NM_001013661.1 49 Gac/Aac 0 +VWA3A UCSF GRCh37 16 22130344 22130344 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 6 76 0 ENST00000389398.5:c.1112A>G p.Glu371Gly p.E371G ENST00000389398 NM_173615.3 371 gAg/gGg 0 +VWF UCSF GRCh37 12 6101129 6101129 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 10 61 0 ENST00000261405.5:c.6654G>A p.Arg2218= p.R2218= ENST00000261405 NM_000552.3 2218 cgG/cgA 0 +WASL UCSF GRCh37 7 123336632 123336632 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 12 140 0 ENST00000223023.4:c.629+1G>A p.X210_splice ENST00000223023 NM_003941.3 0 +WBP4 UCSF GRCh37 13 41639412 41639412 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 15 132 0 ENST00000379487.3:c.251G>A p.Gly84Asp p.G84D ENST00000379487 NM_007187.3 84 gGc/gAc 0 +WBP5 UCSF GRCh37 X 102612721 102612721 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 31 82 0 ENST00000372656.3:c.109G>A p.Glu37Lys p.E37K ENST00000372656 NM_001006614.1 37 Gag/Aag 0 +WBSCR17 UCSF GRCh37 7 70853291 70853291 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 306 53 455 0 ENST00000333538.5:c.493C>T p.Leu165= p.L165= ENST00000333538 NM_022479.2 165 Ctg/Ttg 0 +WBSCR17 UCSF GRCh37 7 70885975 70885975 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 519 65 700 0 ENST00000333538.5:c.846C>T p.Asn282= p.N282= ENST00000333538 NM_022479.2 282 aaC/aaT 0 +WDFY3 UCSF GRCh37 4 85717804 85717804 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 15 186 0 ENST00000295888.4:c.3037G>A p.Glu1013Lys p.E1013K ENST00000295888 NM_014991.4 1013 Gaa/Aaa 0 +WDR11 UCSF GRCh37 10 122612079 122612079 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 24 191 0 ENST00000263461.6:c.130G>A p.Val44Ile p.V44I ENST00000263461 NM_018117.11 44 Gta/Ata 0 +WDR17 UCSF GRCh37 4 177061100 177061100 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 36 286 0 ENST00000280190.4:c.1489G>A p.Ala497Thr p.A497T ENST00000280190 497 Gca/Aca 0 +WDR34 UCSF GRCh37 9 131396082 131396082 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 26 172 0 ENST00000372715.2:c.1552G>A p.Glu518Lys p.E518K ENST00000372715 NM_052844.3 518 Gaa/Aaa 0 +WDR45 UCSF GRCh37 X 48933538 48933538 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 9 40 0 ENST00000376372.3:c.503G>A p.Ser168Asn p.S168N ENST00000376372 NM_001029896.1 168 aGt/aAt 0 +WDR5B UCSF GRCh37 3 122133933 122133933 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 240 38 344 0 ENST00000330689.4:c.443C>T p.Thr148Ile p.T148I ENST00000330689 NM_019069.3 148 aCt/aTt 0 +WDR6 UCSF GRCh37 3 49051328 49051328 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 113 293 0 ENST00000608424.1:c.2361C>T p.Thr787= p.T787= ENST00000608424 787 acC/acT 0 +WDR66 UCSF GRCh37 12 122389392 122389392 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 11 83 0 ENST00000288912.4:c.1276G>A p.Glu426Lys p.E426K ENST00000288912 NM_144668.5 426 Gag/Aag 0 +WDR83 UCSF GRCh37 19 12780631 12780631 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 12 94 0 ENST00000418543.3:c.27G>A p.Arg9= p.R9= ENST00000418543 NM_001099737.2 9 cgG/cgA 0 +WDR87 UCSF GRCh37 19 38376127 38376127 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 60 221 0 ENST00000303868.5:c.8067G>A p.Met2689Ile p.M2689I ENST00000303868 NM_031951.3 2689 atG/atA 0 +WDR90 UCSF GRCh37 16 711344 711344 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 27 207 0 ENST00000293879.4:c.3516C>T p.Val1172= p.V1172= ENST00000293879 1172 gtC/gtT 0 +WDR92 UCSF GRCh37 2 68384413 68384413 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 33 110 0 ENST00000295121.6:c.163G>A p.Asp55Asn p.D55N ENST00000295121 NM_138458.3 55 Gac/Aac 0 +WISP1 UCSF GRCh37 8 134239654 134239654 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 12 50 0 ENST00000250160.6:c.805G>A p.Ala269Thr p.A269T ENST00000250160 NM_003882.3 269 Gca/Aca 0 +WIZ UCSF GRCh37 19 15536149 15536149 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 7 44 0 ENST00000263381.7:c.1512G>A p.Glu504= p.E504= ENST00000263381 NM_021241.2 504 gaG/gaA 0 +WNK2 UCSF GRCh37 9 96024314 96024314 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 85 0 ENST00000297954.4:c.3285C>T p.Asn1095= p.N1095= ENST00000297954 NM_001282394.1 1095 aaC/aaT 0 +WNT11 UCSF GRCh37 11 75902790 75902790 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 36 0 ENST00000322563.3:c.708C>T p.Asp236= p.D236= ENST00000322563 NM_004626.2 236 gaC/gaT 0 +WNT8A UCSF GRCh37 5 137426465 137426465 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 16 128 1 ENST00000398754.1:c.759G>A p.Glu253= p.E253= ENST00000398754 NM_058244.2 253 gaG/gaA 0 +WRN UCSF GRCh37 8 30999288 30999288 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 7 73 0 ENST00000298139.5:c.3230C>T p.Pro1077Leu p.P1077L ENST00000298139 NM_000553.4 1077 cCt/cTt 0 +WRN UCSF GRCh37 8 31015035 31015035 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 7 34 0 ENST00000298139.5:c.3971C>T p.Pro1324Leu p.P1324L ENST00000298139 NM_000553.4 1324 cCc/cTc 0 +WRN UCSF GRCh37 8 30977791 30977791 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 21 163 0 ENST00000298139.5:c.2481C>T p.Gly827= p.G827= ENST00000298139 NM_000553.4 827 ggC/ggT 0 +XAB2 UCSF GRCh37 19 7684699 7684699 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 213 84 246 0 ENST00000358368.4:c.2440G>A p.Val814Ile p.V814I ENST00000358368 NM_020196.2 814 Gtc/Atc 0 +XKR7 UCSF GRCh37 20 30584969 30584969 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 218 35 277 0 ENST00000562532.2:c.1449G>A p.Glu483= p.E483= ENST00000562532 NM_001011718.1 483 gaG/gaA 0 +XPO4 UCSF GRCh37 13 21417107 21417107 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 8 90 0 ENST00000255305.6:c.654G>A p.Gln218= p.Q218= ENST00000255305 218 caG/caA 0 +XPO7 UCSF GRCh37 8 21856752 21856752 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 10 54 0 ENST00000252512.9:c.2579C>T p.Ala860Val p.A860V ENST00000252512 NM_015024.4 860 gCc/gTc 0 +XRCC3 UCSF GRCh37 14 104165783 104165783 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 26 122 0 ENST00000352127.7:c.692G>A p.Arg231Lys p.R231K ENST00000352127 NM_001100118.1 231 aGg/aAg 0 +XRN1 UCSF GRCh37 3 142131443 142131443 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 15 97 0 ENST00000264951.4:c.1656C>T p.Asp552= p.D552= ENST00000264951 NM_019001.3 552 gaC/gaT 0 +XYLT2 UCSF GRCh37 17 48432314 48432314 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 8 59 0 ENST00000017003.2:c.904A>T p.Ser302Cys p.S302C ENST00000017003 NM_022167.2 302 Agc/Tgc 0 +XYLT2 UCSF GRCh37 17 48434120 48434120 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 17 84 0 ENST00000017003.2:c.1731C>T p.Gly577= p.G577= ENST00000017003 NM_022167.2 577 ggC/ggT 0 +YARS2 UCSF GRCh37 12 32908188 32908188 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 12 64 0 ENST00000324868.8:c.621G>A p.Arg207= p.R207= ENST00000324868 NM_001040436.2 207 cgG/cgA 0 +YIF1B UCSF GRCh37 19 38799920 38799920 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 12 117 0 ENST00000339413.6:c.346G>A p.Asp116Asn p.D116N ENST00000339413 NM_001039673.2 116 Gac/Aac 0 +YME1L1 UCSF GRCh37 10 27420824 27420824 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 306 34 259 0 ENST00000326799.3:c.993C>T p.Val331= p.V331= ENST00000326799 NM_139312.2 331 gtC/gtT 0 +ZAN UCSF GRCh37 7 100391805 100391805 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 10 127 0 ENST00000546292.1:c.7850-1013C>T *2617* ENST00000546292 NM_173059.1 0 +ZBED4 UCSF GRCh37 22 50279926 50279926 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 9 157 0 ENST00000216268.5:c.2616G>A p.Glu872= p.E872= ENST00000216268 NM_014838.2 872 gaG/gaA 0 +ZBP1 UCSF GRCh37 20 56179653 56179653 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.012,1000g2011may_all_0.0614,snp132_rs6099680 P24_Rec2 Untested WXS Illumina HiSeq 275 40 402 0 ENST00000371173.3:c.1266G>A p.Gly422= p.G422= ENST00000371173 NM_001160417.1 422 ggG/ggA 0 +ZBTB10 UCSF GRCh37 8 81399803 81399803 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 34 356 0 ENST00000430430.1:c.758C>T p.Ser253Phe p.S253F ENST00000430430 253 tCc/tTc 0 +ZBTB2 UCSF GRCh37 6 151686972 151686972 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 372 68 540 0 ENST00000325144.4:c.1229G>A p.Cys410Tyr p.C410Y ENST00000325144 NM_020861.1 410 tGc/tAc 0 +ZBTB4 UCSF GRCh37 17 7365866 7365866 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 12 102 0 ENST00000311403.4:c.2435G>A p.Gly812Glu p.G812E ENST00000311403 NM_020899.3 812 gGg/gAg 0 +ZBTB4 UCSF GRCh37 17 7369919 7369919 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 15 53 0 ENST00000311403.4:c.202C>T p.Pro68Ser p.P68S ENST00000311403 NM_020899.3 68 Cca/Tca 0 +ZBTB45 UCSF GRCh37 19 59028727 59028727 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 30 215 0 ENST00000354590.3:c.314C>T p.Ala105Val p.A105V ENST00000354590 NM_032792.2 105 gCc/gTc 0 +ZBTB47 UCSF GRCh37 3 42701201 42701201 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 13 115 0 ENST00000232974.6:c.1354G>A p.Glu452Lys p.E452K ENST00000232974 452 Gag/Aag 0 +ZBTB47 UCSF GRCh37 3 42701253 42701253 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 10 83 0 ENST00000232974.6:c.1406G>A p.Gly469Asp p.G469D ENST00000232974 469 gGc/gAc 0 +ZBTB7A UCSF GRCh37 19 4054382 4054382 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 34 133 0 ENST00000322357.4:c.849G>A p.Leu283= p.L283= ENST00000322357 NM_015898.2 283 ctG/ctA 0 +ZC3H12B UCSF GRCh37 X 64718939 64718939 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 11 82 0 ENST00000338957.4:c.809G>A p.Arg270Lys p.R270K ENST00000338957 NM_001010888.3 270 aGa/aAa 0 +ZC3H12B UCSF GRCh37 X 64722305 64722305 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 50 223 1 ENST00000338957.4:c.1727C>T p.Ala576Val p.A576V ENST00000338957 NM_001010888.3 576 gCc/gTc 0 +ZC3H12C UCSF GRCh37 11 110007586 110007586 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 193 25 224 0 ENST00000278590.3:c.220G>A p.Gly74Arg p.G74R ENST00000278590 NM_033390.1 74 Ggg/Agg 0 +ZC3H12C UCSF GRCh37 11 110036273 110036273 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 218 30 261 0 ENST00000278590.3:c.2463G>A p.Arg821= p.R821= ENST00000278590 NM_033390.1 821 cgG/cgA 0 +ZC3H7B UCSF GRCh37 22 41745306 41745306 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 9 50 0 ENST00000352645.4:c.1948+1G>A p.X650_splice ENST00000352645 NM_017590.5 0 +ZC3HAV1 UCSF GRCh37 7 138761068 138761068 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 69 238 0 ENST00000242351.5:c.1661C>T p.Thr554Met p.T554M ENST00000242351 NM_020119.3 554 aCg/aTg 0 +ZC3HAV1L UCSF GRCh37 7 138720571 138720571 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 42 0 ENST00000275766.1:c.193G>A p.Ala65Thr p.A65T ENST00000275766 NM_080660.3 65 Gcc/Acc 0 +ZCCHC11 UCSF GRCh37 1 52991715 52991715 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 273 45 425 0 ENST00000371544.3:c.238C>T p.Leu80Phe p.L80F ENST00000371544 NM_015269.2 80 Ctt/Ttt 0 +ZCCHC2 UCSF GRCh37 18 60217659 60217659 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 13 136 0 ENST00000269499.5:c.1279G>A p.Glu427Lys p.E427K ENST00000269499 NM_017742.4 427 Gaa/Aaa 0 +ZCCHC3 UCSF GRCh37 20 279310 279310 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 44 122 0 ENST00000382352.3:c.1083G>A p.Gly361= p.G361= ENST00000382352 NM_033089.6 361 ggG/ggA 0 +ZDHHC13 UCSF GRCh37 11 19177349 19177349 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 34 320 0 ENST00000446113.2:c.880C>T p.Leu294= p.L294= ENST00000446113 NM_019028.2 294 Ctg/Ttg 0 +ZDHHC5 UCSF GRCh37 11 57467469 57467469 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 12 70 0 ENST00000287169.3:c.2114G>A p.Gly705Glu p.G705E ENST00000287169 NM_015457.2 705 gGg/gAg 0 +ZDHHC8 UCSF GRCh37 22 20132889 20132889 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 13 110 0 ENST00000334554.7:c.2264G>A p.Gly755Asp p.G755D ENST00000334554 NM_013373.3 755 gGc/gAc 0 +ZFHX2 UCSF GRCh37 14 24001885 24001885 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 23 226 0 ENST00000419474.3:c.2450C>T p.Ser817Phe p.S817F ENST00000419474 NM_033400.2 817 tCc/tTc 0 +ZFHX3 UCSF GRCh37 16 72829408 72829408 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 29 247 0 ENST00000268489.5:c.7173C>T p.Tyr2391= p.Y2391= ENST00000268489 NM_006885.3 2391 taC/taT 0 +ZFHX4 UCSF GRCh37 8 77619971 77619971 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 15 173 0 ENST00000521891.2:c.2781G>A p.Glu927= p.E927= ENST00000521891 NM_024721.4 927 gaG/gaA 0 +ZFP106 UCSF GRCh37 15 42743419 42743419 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 29 182 0 ENST00000263805.4:c.982G>A p.Asp328Asn p.D328N ENST00000263805 NM_022473.1 328 Gac/Aac 0 +ZFP36 UCSF GRCh37 19 39898603 39898603 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 214 27 270 1 ENST00000248673.3:c.245G>A p.Arg82His p.R82H ENST00000248673 NM_003407.3 82 cGc/cAc 0 +ZFP41 UCSF GRCh37 8 144332454 144332454 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 17 371 0 ENST00000330701.4:c.441G>A p.Glu147= p.E147= ENST00000330701 NM_173832.4 147 gaG/gaA 0 +ZFPM2 UCSF GRCh37 8 106814665 106814665 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 182 29 280 0 ENST00000407775.2:c.2355C>T p.His785= p.H785= ENST00000407775 NM_012082.3 785 caC/caT 0 +ZFYVE1 UCSF GRCh37 14 73464894 73464894 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 22 200 0 ENST00000556143.1:c.613C>T p.Arg205Cys p.R205C ENST00000556143 NM_021260.2 205 Cgt/Tgt 0 +ZFYVE26 UCSF GRCh37 14 68282515 68282515 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 11 77 0 ENST00000347230.4:c.166G>A p.Ala56Thr p.A56T ENST00000347230 NM_015346.3 56 Gca/Aca 0 +ZFYVE9 UCSF GRCh37 1 52811820 52811820 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 25 71 0 ENST00000287727.3:c.4205G>A p.Gly1402Glu p.G1402E ENST00000287727 NM_004799.3 1402 gGa/gAa 0 +ZG16B UCSF GRCh37 16 2881803 2881803 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 19 132 0 ENST00000382280.3:c.270G>A p.Gln90= p.Q90= ENST00000382280 NM_145252.2 90 caG/caA 0 +ZMYND15 UCSF GRCh37 17 4647099 4647099 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 13 105 0 ENST00000433935.1:c.1335C>T p.Ala445= p.A445= ENST00000433935 NM_001136046.2 445 gcC/gcT 0 +ZNF117 UCSF GRCh37 7 64438752 64438752 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 14 123 0 ENST00000282869.6:c.1197C>T p.His399= p.H399= ENST00000282869 NM_015852.3 399 caC/caT 0 +ZNF132 UCSF GRCh37 19 58945830 58945830 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 11 99 0 ENST00000254166.3:c.981C>T p.Thr327= p.T327= ENST00000254166 NM_003433.3 327 acC/acT 0 +ZNF155 UCSF GRCh37 19 44500799 44500799 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 22 171 0 ENST00000270014.2:c.790G>A p.Ala264Thr p.A264T ENST00000270014 NM_198089.2 264 Gca/Aca 0 +ZNF177 UCSF GRCh37 19 9491788 9491788 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 23 206 0 ENST00000589262.1:c.781C>T p.His261Tyr p.H261Y ENST00000589262 NM_001172651.1 261 Cat/Tat 0 +ZNF180 UCSF GRCh37 19 44981244 44981244 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 12 144 0 ENST00000221327.4:c.1454G>A p.Arg485Lys p.R485K ENST00000221327 NM_013256.4 485 aGa/aAa 0 +ZNF185 UCSF GRCh37 X 152100223 152100223 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 8 83 0 ENST00000370268.4:c.922C>T p.Pro308Ser p.P308S ENST00000370268 308 Cca/Tca 0 +ZNF185 UCSF GRCh37 X 152083371 152083371 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 2 12 17 0 ENST00000370268.4:c.152G>A p.Arg51His p.R51H ENST00000370268 51 cGc/cAc 0 +ZNF192 UCSF GRCh37 6 28116521 28116521 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 15 166 0 ENST00000330236.6:c.336G>A p.Lys112= p.K112= ENST00000330236 NM_001278122.1 112 aaG/aaA 0 +ZNF20 UCSF GRCh37 19 12244492 12244492 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 598 67 626 0 ENST00000334213.5:c.509C>T p.Pro170Leu p.P170L ENST00000334213 NM_001203250.1 170 cCc/cTc 0 +ZNF229 UCSF GRCh37 19 44933981 44933981 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 106 465 0 ENST00000588931.1:c.975G>A p.Glu325= p.E325= ENST00000588931 NM_014518.2 325 gaG/gaA 0 +ZNF24 UCSF GRCh37 18 32920385 32920385 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 16 136 0 ENST00000261332.6:c.230G>A p.Cys77Tyr p.C77Y ENST00000261332 NM_006965.2 77 tGc/tAc 0 +ZNF24 UCSF GRCh37 18 32920566 32920566 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 33 245 0 ENST00000261332.6:c.49C>T p.Pro17Ser p.P17S ENST00000261332 NM_006965.2 17 Cca/Tca 0 +ZNF24 UCSF GRCh37 18 32917559 32917559 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 34 289 0 ENST00000261332.6:c.744G>A p.Lys248= p.K248= ENST00000261332 NM_006965.2 248 aaG/aaA 0 +ZNF253 UCSF GRCh37 19 20003111 20003111 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 3 25 0 ENST00000589717.1:c.1055C>T p.Ser352Phe p.S352F ENST00000589717 NM_021047.2 352 tCc/tTc 0 +ZNF253 UCSF GRCh37 19 20003434 20003434 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 4 14 0 ENST00000589717.1:c.1378G>A p.Ala460Thr p.A460T ENST00000589717 NM_021047.2 460 Gct/Act 0 +ZNF259 UCSF GRCh37 11 116654325 116654325 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 21 112 0 ENST00000227322.3:c.902G>A p.Gly301Glu p.G301E ENST00000227322 NM_003904.3 301 gGa/gAa 0 +ZNF276 UCSF GRCh37 16 89790020 89790020 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.011,1000g2011may_all_0.0260,snp132_rs34629175 P24_Rec2 Untested WXS Illumina HiSeq 32 6 95 0 ENST00000443381.2:c.909C>T p.Pro303= p.P303= ENST00000443381 NM_001113525.1 303 ccC/ccT 0 +ZNF286A UCSF GRCh37 17 15611511 15611511 + missense_variant,NMD_transcript_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 7 94 0 ENST00000413242.2:c.284G>A p.Gly95Glu p.G95E ENST00000413242 95 gGa/gAa 0 +ZNF287 UCSF GRCh37 17 16456713 16456713 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 16 165 0 ENST00000395824.1:c.743C>T p.Thr248Ile p.T248I ENST00000395824 248 aCt/aTt 0 +ZNF292 UCSF GRCh37 6 87966064 87966064 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 215 31 294 0 ENST00000369577.3:c.2717C>T p.Ser906Phe p.S906F ENST00000369577 NM_015021.1 906 tCt/tTt 0 +ZNF295 UCSF GRCh37 21 43412147 43412147 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 144 21 195 0 ENST00000310826.5:c.2058G>A p.Lys686= p.K686= ENST00000310826 NM_001098402.1 686 aaG/aaA 0 +ZNF296 UCSF GRCh37 19 45575741 45575741 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 10 100 0 ENST00000303809.2:c.546G>A p.Leu182= p.L182= ENST00000303809 NM_145288.1 182 ctG/ctA 0 +ZNF318 UCSF GRCh37 6 43306112 43306112 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 37 234 0 ENST00000361428.2:c.5624G>A p.Arg1875Lys p.R1875K ENST00000361428 NM_014345.2 1875 aGg/aAg 0 +ZNF318 UCSF GRCh37 6 43323442 43323442 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 335 68 486 0 ENST00000361428.2:c.1630G>A p.Glu544Lys p.E544K ENST00000361428 NM_014345.2 544 Gag/Aag 0 +ZNF343 UCSF GRCh37 20 2463888 2463888 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 276 42 392 0 ENST00000278772.4:c.1719G>A p.Gly573= p.G573= ENST00000278772 NM_024325.4 573 ggG/ggA 0 +ZNF35 UCSF GRCh37 3 44694194 44694194 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 6 71 0 ENST00000396056.2:c.337+1G>A p.X113_splice ENST00000396056 NM_003420.3 0 +ZNF385C UCSF GRCh37 17 40183686 40183686 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 30 142 0 ENST00000436535.3:c.627C>T p.Ser209= p.S209= ENST00000436535 209 tcC/tcT 0 +ZNF396 UCSF GRCh37 18 32953488 32953488 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 7 70 0 ENST00000589332.1:c.494G>A p.Ser165Asn p.S165N ENST00000589332 165 aGc/aAc 0 +ZNF407 UCSF GRCh37 18 72775186 72775186 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 27 232 0 ENST00000299687.5:c.5509G>A p.Ala1837Thr p.A1837T ENST00000299687 NM_017757.2 1837 Gcg/Acg 0 +ZNF414 UCSF GRCh37 19 8576704 8576704 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 7 26 0 ENST00000255616.8:c.671C>T p.Pro224Leu p.P224L ENST00000255616 NM_032370.2 224 cCg/cTg 0 +ZNF418 UCSF GRCh37 19 58437815 58437815 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 20 224 0 ENST00000396147.1:c.1734C>T p.Leu578= p.L578= ENST00000396147 NM_133460.1 578 ctC/ctT 0 +ZNF439 UCSF GRCh37 19 11979318 11979318 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 9 88 0 ENST00000304030.2:c.1434C>T p.Val478= p.V478= ENST00000304030 NM_152262.2 478 gtC/gtT 0 +ZNF44 UCSF GRCh37 19 12384680 12384680 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 395 44 420 0 ENST00000356109.5:c.534C>T p.His178= p.H178= ENST00000356109 NM_001164276.1 178 caC/caT 0 +ZNF460 UCSF GRCh37 19 57802913 57802913 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 23 202 0 ENST00000360338.3:c.1004C>T p.Pro335Leu p.P335L ENST00000360338 NM_006635.3 335 cCc/cTc 0 +ZNF48 UCSF GRCh37 16 30409691 30409691 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 399 75 496 0 ENST00000320159.2:c.1120C>T p.Leu374Phe p.L374F ENST00000320159 NM_152652.2 374 Ctt/Ttt 0 +ZNF496 UCSF GRCh37 1 247492641 247492641 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 18 151 0 ENST00000294753.4:c.240G>A p.Gln80= p.Q80= ENST00000294753 NM_032752.1 80 caG/caA 0 +ZNF513 UCSF GRCh37 2 27601401 27601401 + synonymous_variant Silent SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 22 78 0 ENST00000323703.6:c.732T>C p.Cys244= p.C244= ENST00000323703 NM_144631.5 244 tgT/tgC 0 +ZNF517 UCSF GRCh37 8 146033708 146033708 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 9 65 0 ENST00000359971.3:c.1407G>A p.Gln469= p.Q469= ENST00000359971 NM_213605.2 469 caG/caA 0 +ZNF518B UCSF GRCh37 4 10445190 10445190 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 208 32 277 1 ENST00000326756.3:c.2763G>A p.Arg921= p.R921= ENST00000326756 NM_053042.2 921 agG/agA 0 +ZNF521 UCSF GRCh37 18 22805963 22805963 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 30 217 0 ENST00000361524.3:c.1919G>A p.Gly640Asp p.G640D ENST00000361524 NM_015461.2 640 gGt/gAt 0 +ZNF526 UCSF GRCh37 19 42729057 42729057 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 269 37 377 0 ENST00000301215.3:c.502G>A p.Val168Ile p.V168I ENST00000301215 NM_133444.1 168 Gta/Ata 0 +ZNF543 UCSF GRCh37 19 57839308 57839308 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 29 196 0 ENST00000321545.4:c.478G>A p.Asp160Asn p.D160N ENST00000321545 NM_213598.3 160 Gat/Aat 0 +ZNF544 UCSF GRCh37 19 58757770 58757770 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.010,1000g2011may_all_0.00554 P24_Rec2 Untested WXS Illumina HiSeq 81 14 79 0 ENST00000269829.4:c.137C>T p.Thr46Ile p.T46I ENST00000269829 NM_014480.2 46 aCc/aTc 0 +ZNF544 UCSF GRCh37 19 58772931 58772931 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 40 238 0 ENST00000269829.4:c.959G>A p.Gly320Asp p.G320D ENST00000269829 NM_014480.2 320 gGc/gAc 0 +ZNF546 UCSF GRCh37 19 40521124 40521124 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 8 67 0 ENST00000347077.4:c.1947C>T p.Ser649= p.S649= ENST00000347077 NM_178544.3 649 agC/agT 0 +ZNF552 UCSF GRCh37 19 58319917 58319917 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 80 263 0 ENST00000391701.1:c.715C>T p.Pro239Ser p.P239S ENST00000391701 NM_024762.3 239 Cct/Tct 0 +ZNF563 UCSF GRCh37 19 12429560 12429560 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 5 54 0 ENST00000293725.5:c.1279G>A p.Gly427Arg p.G427R ENST00000293725 NM_145276.2 427 Ggg/Agg 0 +ZNF571 UCSF GRCh37 19 38056308 38056308 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 10 75 0 ENST00000328550.2:c.1022G>A p.Gly341Glu p.G341E ENST00000328550 341 gGg/gAg 0 +ZNF573 UCSF GRCh37 19 38230154 38230154 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 20 239 0 ENST00000536220.1:c.973C>T p.Pro325Ser p.P325S ENST00000536220 NM_001172689.1 325 Ccc/Tcc 0 +ZNF574 UCSF GRCh37 19 42584099 42584099 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 21 211 0 ENST00000359044.4:c.1341C>T p.Ala447= p.A447= ENST00000359044 NM_022752.5 447 gcC/gcT 0 +ZNF577 UCSF GRCh37 19 52376415 52376415 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 212 36 340 0 ENST00000301399.5:c.828G>A p.Gly276= p.G276= ENST00000301399 NM_032679.2 276 ggG/ggA 0 +ZNF585B UCSF GRCh37 19 37680656 37680656 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 298 55 509 0 ENST00000532828.2:c.200-1G>A p.X67_splice ENST00000532828 NM_152279.3 0 +ZNF593 UCSF GRCh37 1 26496631 26496631 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 24 204 0 ENST00000374266.5:c.157C>T p.Pro53Ser p.P53S ENST00000374266 NM_015871.4 53 Ccc/Tcc 0 +ZNF599 UCSF GRCh37 19 35250905 35250905 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 8 93 0 ENST00000329285.8:c.801G>A p.Arg267= p.R267= ENST00000329285 NM_001007248.2 267 agG/agA 0 +ZNF609 UCSF GRCh37 15 64967341 64967341 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 36 294 0 ENST00000326648.3:c.2288C>T p.Ser763Phe p.S763F ENST00000326648 NM_015042.1 763 tCt/tTt 0 +ZNF613 UCSF GRCh37 19 52448084 52448084 + synonymous_variant Silent SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 239 30 358 0 ENST00000293471.6:c.948T>C p.His316= p.H316= ENST00000293471 NM_001031721.3 316 caT/caC 0 +ZNF618 UCSF GRCh37 9 116778436 116778436 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 12 113 0 ENST00000374126.5:c.755-539G>A *252* ENST00000374126 0 +ZNF649 UCSF GRCh37 19 52394838 52394838 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 357 57 541 0 ENST00000354957.3:c.551G>A p.Gly184Glu p.G184E ENST00000354957 NM_023074.3 184 gGg/gAg 0 +ZNF662 UCSF GRCh37 3 42956793 42956793 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 187 110 427 0 ENST00000440367.2:c.1228C>T p.His410Tyr p.H410Y ENST00000440367 NM_207404.3 410 Cat/Tat 0 +ZNF689 UCSF GRCh37 16 30615959 30615959 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 8 77 0 ENST00000287461.3:c.1129G>A p.Asp377Asn p.D377N ENST00000287461 NM_138447.2 377 Gac/Aac 0 +ZNF692 UCSF GRCh37 1 249151525 249151525 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 22 106 0 ENST00000306601.4:c.383C>T p.Pro128Leu p.P128L ENST00000306601 NM_017865.3 128 cCt/cTt 0 +ZNF699 UCSF GRCh37 19 9415792 9415792 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 22 194 0 ENST00000308650.3:c.4G>A p.Glu2Lys p.E2K ENST00000308650 NM_198535.1 2 Gag/Aag 0 +ZNF700 UCSF GRCh37 19 12059222 12059222 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 4 34 0 ENST00000254321.5:c.383G>A p.Ser128Asn p.S128N ENST00000254321 NM_144566.2 128 aGc/aAc 0 +ZNF709 UCSF GRCh37 19 12575879 12575879 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 28 97 0 ENST00000397732.3:c.857G>A p.Gly286Asp p.G286D ENST00000397732 NM_152601.3 286 gGt/gAt 0 +ZNF711 UCSF GRCh37 X 84525896 84525896 + missense_variant Missense_Mutation SNP G G C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 36 64 0 ENST00000276123.3:c.1348G>C p.Glu450Gln p.E450Q ENST00000276123 450 Gaa/Caa 0 +ZNF74 UCSF GRCh37 22 20754989 20754989 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 31 249 0 ENST00000400451.2:c.188C>T p.Pro63Leu p.P63L ENST00000400451 NM_003426.3 63 cCt/cTt 0 +ZNF768 UCSF GRCh37 16 30536258 30536258 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 10 96 0 ENST00000380412.5:c.1203C>T p.Phe401= p.F401= ENST00000380412 NM_024671.3 401 ttC/ttT 0 +ZNF770 UCSF GRCh37 15 35274747 35274747 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 146 600 0 ENST00000356321.4:c.889C>T p.Pro297Ser p.P297S ENST00000356321 NM_014106.3 297 Cca/Tca 0 +ZNF776 UCSF GRCh37 19 58265946 58265946 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 12 91 0 ENST00000317178.5:c.1448C>T p.Ser483Phe p.S483F ENST00000317178 NM_173632.3 483 tCt/tTt 0 +ZNF777 UCSF GRCh37 7 149152608 149152608 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 20 173 0 ENST00000247930.4:c.506C>T p.Ser169Phe p.S169F ENST00000247930 NM_015694.2 169 tCt/tTt 0 +ZNF780A UCSF GRCh37 19 40580810 40580810 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 16 141 0 ENST00000340963.5:c.1539C>T p.Tyr513= p.Y513= ENST00000340963 513 taC/taT 0 +ZNF783 UCSF GRCh37 7 148963769 148963769 + missense_variant,NMD_transcript_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 10 45 0 ENST00000378052.1:c.368G>A p.Arg123Lys p.R123K ENST00000378052 123 aGg/aAg 0 +ZNF785 UCSF GRCh37 16 30594687 30594687 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 24 324 1 ENST00000395216.2:c.412G>A p.Val138Ile p.V138I ENST00000395216 NM_152458.6 138 Gtc/Atc 0 +ZNF827 UCSF GRCh37 4 146824083 146824083 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 22 249 0 ENST00000508784.1:c.328G>A p.Asp110Asn p.D110N ENST00000508784 110 Gac/Aac 0 +ZNF835 UCSF GRCh37 19 57175523 57175523 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 70 170 0 ENST00000537055.2:c.1044C>T p.His348= p.H348= ENST00000537055 NM_001005850.2 348 caC/caT 0 +ZNF836 UCSF GRCh37 19 52660772 52660772 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 13 149 0 ENST00000597252.1:c.164C>T p.Thr55Ile p.T55I ENST00000597252 55 aCc/aTc 0 +ZNF850 UCSF GRCh37 19 37253264 37253264 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 7 51 0 ENST00000591344.1:c.82C>T p.Gln28Ter p.Q28* ENST00000591344 NM_001193552.1 28 Cag/Tag 0 +ZNF91 UCSF GRCh37 19 23542428 23542428 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 3 12 0 ENST00000300619.7:c.3353C>T p.Ser1118Phe p.S1118F ENST00000300619 NM_003430.2 1118 tCc/tTc 0 +ZNF91 UCSF GRCh37 19 23543844 23543844 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 4 24 0 ENST00000300619.7:c.1937C>T p.Ala646Val p.A646V ENST00000300619 NM_003430.2 646 gCt/gTt 0 +ZNF92 UCSF GRCh37 7 64864293 64864293 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 6 38 0 ENST00000328747.7:c.1266G>A p.Glu422= p.E422= ENST00000328747 NM_152626.2 422 gaG/gaA 0 +ZNFX1 UCSF GRCh37 20 47887104 47887104 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 309 50 471 0 ENST00000371752.1:c.1245G>A p.Arg415= p.R415= ENST00000371752 415 agG/agA 0 +ZSCAN2 UCSF GRCh37 15 85147240 85147240 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 8 40 0 ENST00000448803.2:c.82G>A p.Glu28Lys p.E28K ENST00000448803 NM_181877.3 28 Gag/Aag 0 +ZSCAN2 UCSF GRCh37 15 85164314 85164314 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 15 111 0 ENST00000448803.2:c.888C>T p.His296= p.H296= ENST00000448803 NM_181877.3 296 caC/caT 0 +ZSCAN2 UCSF GRCh37 15 85164869 85164869 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 7 93 0 ENST00000448803.2:c.1443G>A p.Glu481= p.E481= ENST00000448803 NM_181877.3 481 gaG/gaA 0 +ZSCAN20 UCSF GRCh37 1 33954780 33954780 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 29 152 0 ENST00000361328.3:c.670G>A p.Ala224Thr p.A224T ENST00000361328 NM_145238.3 224 Gct/Act 0 +ZSCAN29 UCSF GRCh37 15 43656390 43656390 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 27 233 0 ENST00000396976.2:c.1413C>T p.Ser471= p.S471= ENST00000396976 NM_152455.3 471 agC/agT 0 +ZSCAN5A UCSF GRCh37 19 56733157 56733157 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 12 97 0 ENST00000391713.1:c.1278C>T p.Tyr426= p.Y426= ENST00000391713 NM_024303.1 426 taC/taT 0 +ZW10 UCSF GRCh37 11 113619026 113619026 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 26 340 0 ENST00000200135.3:c.1042G>A p.Val348Ile p.V348I ENST00000200135 NM_004724.3 348 Gtt/Att 0 +ABCA4 UCSF GRCh37 1 94497337 94497337 + synonymous_variant Silent SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 39 21 56 0 ENST00000370225.3:c.4125G>A p.Ala1375= p.A1375= ENST00000370225 NM_000350.2 1375 gcG/gcA 0 +ATRX UCSF GRCh37 X 76918873 76918874 + frameshift_variant,splice_region_variant Frame_Shift_Del DEL TT TT - NOVEL P25_Pri Untested WXS Illumina HiSeq 33 0 ENST00000373344.5:c.4117_4118del p.Lys1373GlyfsTer4 p.K1373Gfs*4 ENST00000373344 NM_000489.3 1373 AAg/g 0 +CCNA1 UCSF GRCh37 13 37007335 37007335 + stop_gained Nonsense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 48 47 110 0 ENST00000255465.4:c.274C>T p.Gln92Ter p.Q92* ENST00000255465 92 Cag/Tag 0 +CDHR5 UCSF GRCh37 11 618683 618683 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.023,1000g2011may_all_0.0158 P25_Pri Untested WXS Illumina HiSeq 39 6 37 1 ENST00000358353.3:c.1876A>G p.Thr626Ala p.T626A ENST00000358353 626 Acc/Gcc 0 +CFHR4 UCSF GRCh37 1 196876134 196876134 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 51 38 92 0 ENST00000367416.2:c.580G>A p.Glu194Lys p.E194K ENST00000367416 NM_001201551.1 194 Gaa/Aaa 0 +DNAJC11 UCSF GRCh37 1 6727803 6727804 + frameshift_variant Frame_Shift_Del DEL TC TC - 1000g2010nov_all P25_Pri Untested WXS Illumina HiSeq 8 0 ENST00000377577.5:c.343_344delGA p.Glu115ArgfsTer25 p.E115Rfs*25 ENST00000377577 NM_018198.3 115 GAa/a 0 +FAM48A UCSF GRCh37 13 37583915 37583915 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 48 10 60 0 ENST00000350612.6:c.2234T>C p.Met745Thr p.M745T ENST00000350612 NM_001014286.2 745 aTg/aCg 0 +GSDMD UCSF GRCh37 8 144641513 144641513 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 90 69 146 0 ENST00000262580.4:c.8C>T p.Ser3Leu p.S3L ENST00000262580 NM_024736.6 3 tCg/tTg 0 +HIVEP2 UCSF GRCh37 6 143092015 143092015 + synonymous_variant Silent SNP C C G NOVEL P25_Pri Untested WXS Illumina HiSeq 435 310 810 0 ENST00000012134.2:c.3861G>C p.Gly1287= p.G1287= ENST00000012134 1287 ggG/ggC 0 +HOOK3 UCSF GRCh37 8 42819516 42819519 + frameshift_variant Frame_Shift_Del DEL ACTC ACTC - NOVEL P25_Pri Untested WXS Illumina HiSeq 217 0 ENST00000307602.4:c.679_682del p.Leu227IlefsTer6 p.L227Ifs*6 ENST00000307602 NM_032410.3 226 agACTC/ag 0 +HS6ST1 UCSF GRCh37 2 129075919 129075919 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0243,snp132_rs61732019 P25_Pri Untested WXS Illumina HiSeq 11 4 28 1 ENST00000259241.6:c.219C>T p.Arg73= p.R73= ENST00000259241 NM_004807.2 73 cgC/cgT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 20 19 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFNAR2 UCSF GRCh37 21 34635055 34635084 + intron_variant Intron DEL ACAGCTGATACGGACTCTCTCTCTCTTTTT ACAGCTGATACGGACTCTCTCTCTCTTTTT TACAGCTGATATGGACTCTCTCTCTC NOVEL P25_Pri Untested WXS Illumina HiSeq 31 0 ENST00000342136.4:c.841-43_841-14delinsTACAGCTGATATGGACTCTCTCTCTC *281* ENST00000342136 0 +KIAA1524 UCSF GRCh37 3 108276093 108276093 + missense_variant Missense_Mutation SNP T T A NOVEL P25_Pri Untested WXS Illumina HiSeq 64 28 103 0 ENST00000295746.8:c.2182A>T p.Thr728Ser p.T728S ENST00000295746 NM_020890.2 728 Aca/Tca 0 +KRT75 UCSF GRCh37 12 52825420 52825420 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 129 87 202 0 ENST00000252245.5:c.777C>T p.Asp259= p.D259= ENST00000252245 NM_004693.2 259 gaC/gaT 0 +MFSD7 UCSF GRCh37 4 680052 680052 + missense_variant Missense_Mutation SNP G G C NOVEL P25_Pri Untested WXS Illumina HiSeq 60 26 58 0 ENST00000404286.2:c.334C>G p.Leu112Val p.L112V ENST00000404286 NM_032219.2 112 Cta/Gta 0 +MFSD7 UCSF GRCh37 4 679684 679684 + synonymous_variant Silent SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 316 136 294 0 ENST00000404286.2:c.525C>T p.Val175= p.V175= ENST00000404286 NM_032219.2 175 gtC/gtT 0 +MUC16 UCSF GRCh37 19 9065233 9065233 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 100 77 162 1 ENST00000397910.4:c.22213T>C p.Ser7405Pro p.S7405P ENST00000397910 NM_024690.2 7405 Tct/Cct 0 +NAGS UCSF GRCh37 17 42084844 42084844 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 81 42 72 0 ENST00000293404.3:c.1250C>T p.Ser417Phe p.S417F ENST00000293404 NM_153006.2 417 tCc/tTc 0 +NOTCH4 UCSF GRCh37 6 32169238 32169238 + synonymous_variant Silent SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 126 123 222 0 ENST00000375023.3:c.3795C>T p.Asn1265= p.N1265= ENST00000375023 NM_004557.3 1265 aaC/aaT 0 +NRXN1 UCSF GRCh37 2 50464102 50464102 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 116 40 176 0 ENST00000406316.2:c.3371C>T p.Thr1124Met p.T1124M ENST00000406316 NM_004801.4 1124 aCg/aTg 0 +NSRP1 UCSF GRCh37 17 28506119 28506119 + missense_variant Missense_Mutation SNP T T G NOVEL P25_Pri Untested WXS Illumina HiSeq 8 7 9 0 ENST00000247026.5:c.312T>G p.Ile104Met p.I104M ENST00000247026 NM_032141.3 104 atT/atG 0 +NXF1 UCSF GRCh37 11 62564841 62564841 + synonymous_variant Silent SNP G G T NOVEL P25_Pri Untested WXS Illumina HiSeq 25 32 52 0 ENST00000294172.2:c.1071C>A p.Pro357= p.P357= ENST00000294172 NM_006362.4 357 ccC/ccA 0 +ODZ3 UCSF GRCh37 4 183574952 183574952 + missense_variant Missense_Mutation SNP G G C NOVEL P25_Pri Untested WXS Illumina HiSeq 209 128 384 0 ENST00000511685.1:c.1017G>C p.Gln339His p.Q339H ENST00000511685 339 caG/caC 0 +OGFR UCSF GRCh37 20 61441865 61441865 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 101 44 134 0 ENST00000290291.6:c.413G>A p.Arg138Gln p.R138Q ENST00000290291 NM_007346.2 138 cGa/cAa 0 +OR13C8 UCSF GRCh37 9 107332403 107332403 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 80 9 81 0 ENST00000335040.1:c.955G>A p.Gly319Arg p.G319R ENST00000335040 NM_001004483.1 319 Gga/Aga 0 +OR2M7 UCSF GRCh37 1 248487504 248487504 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 12 2 22 0 ENST00000317965.2:c.367T>C p.Tyr123His p.Y123H ENST00000317965 NM_001004691.1 123 Tac/Cac 0 +PCDHB7 UCSF GRCh37 5 140553940 140553940 + synonymous_variant Silent SNP G G A snp132_rs17844458 P25_Pri Untested WXS Illumina HiSeq 14 7 9 0 ENST00000231137.3:c.1524G>A p.Ala508= p.A508= ENST00000231137 NM_018940.2 508 gcG/gcA 0 +PDE6B UCSF GRCh37 4 659088 659088 + synonymous_variant Silent SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 61 31 75 0 ENST00000496514.1:c.2238G>A p.Leu746= p.L746= ENST00000496514 746 ttG/ttA 0 +PUS10 UCSF GRCh37 2 61181117 61181117 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Pri Untested WXS Illumina HiSeq 172 55 214 0 ENST00000316752.6:c.1141A>G p.Asn381Asp p.N381D ENST00000316752 NM_144709.2 381 Aat/Gat 0 +PYCR2 UCSF GRCh37 1 226108161 226108163 + inframe_deletion In_Frame_Del DEL CTT CTT - NOVEL P25_Pri Untested WXS Illumina HiSeq 7 0 ENST00000343818.6:c.955_957del p.Lys319del p.K319del ENST00000343818 NM_013328.3 319 AAG/- 0 +QRICH2 UCSF GRCh37 17 74288509 74288510 + inframe_insertion In_Frame_Ins INS - - CTGCACCAGGTTGGACCAAACCACGCTGAT NOVEL P25_Pri Untested WXS Illumina HiSeq 9 0 ENST00000262765.5:c.1800_1801insATCAGCGTGGTTTGGTCCAACCTGGTGCAG p.Ala600_Asp601insIleSerValValTrpSerAsnLeuValGln p.A600_D601insISVVWSNLVQ ENST00000262765 NM_032134.1 600 -/ATCAGCGTGGTTTGGTCCAACCTGGTGCAG 0 +RPS6KC1 UCSF GRCh37 1 213415490 213415492 + inframe_deletion In_Frame_Del DEL AAA AAA - NOVEL P25_Pri Untested WXS Illumina HiSeq 7 0 ENST00000366960.3:c.2674_2676del p.Lys892del p.K892del ENST00000366960 NM_012424.3 891 AAA/- 0 +SLC23A2 UCSF GRCh37 20 4850569 4850570 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P25_Pri Untested WXS Illumina HiSeq 13 0 ENST00000338244.1:c.1233dup p.Ile412HisfsTer18 p.I412Hfs*18 ENST00000338244 NM_005116.5 411 ccc/ccCc 0 +SLC9A1 UCSF GRCh37 1 27440317 27440317 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 142 17 142 0 ENST00000263980.3:c.813G>A p.Val271= p.V271= ENST00000263980 NM_003047.4 271 gtG/gtA 0 +SPEN UCSF GRCh37 1 16257644 16257644 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 128 131 237 0 ENST00000375759.3:c.4909G>A p.Val1637Ile p.V1637I ENST00000375759 NM_015001.2 1637 Gtt/Att 0 +STXBP5 UCSF GRCh37 6 147648347 147648347 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 41 36 94 0 ENST00000321680.6:c.2015A>G p.Tyr672Cys p.Y672C ENST00000321680 NM_001127715.2 672 tAt/tGt 0 +TCF12 UCSF GRCh37 15 57524581 57524582 + frameshift_variant Frame_Shift_Del DEL AT AT - NOVEL P25_Pri Untested WXS Illumina HiSeq 13 0 ENST00000267811.5:c.778_779del p.Met260ValfsTer5 p.M260Vfs*5 ENST00000267811 NM_003205.3 260 ATg/g 0 +TEP1 UCSF GRCh37 14 20871601 20871601 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 148 26 131 0 ENST00000262715.5:c.1201G>A p.Glu401Lys p.E401K ENST00000262715 NM_007110.4 401 Gag/Aag 0 +THAP5 UCSF GRCh37 7 108205526 108205526 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P25_Pri Untested WXS Illumina HiSeq 10 0 ENST00000415914.3:c.297delA p.Lys99AsnfsTer25 p.K99Nfs*25 ENST00000415914 NM_001130475.1 99 aaA/aa 0 +TRPM1 UCSF GRCh37 15 31334362 31334362 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.012,1000g2011may_all_0.02529,snp132_rs17815774 P25_Pri Untested WXS Illumina HiSeq 91 49 186 0 ENST00000397795.2:c.1813G>A p.Val605Met p.V605M ENST00000397795 NM_002420.5 605 Gtg/Atg 0 +VPS35 UCSF GRCh37 16 46706301 46706301 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 119 16 360 0 ENST00000299138.7:c.1244T>C p.Val415Ala p.V415A ENST00000299138 NM_018206.4 415 gTc/gCc 0 +YARS UCSF GRCh37 1 33245060 33245060 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 173 170 343 0 ENST00000373477.4:c.1399G>A p.Val467Met p.V467M ENST00000373477 NM_003680.3 467 Gtg/Atg 0 +YES1 UCSF GRCh37 18 756607 756607 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 75 47 138 0 ENST00000314574.4:c.221C>T p.Ala74Val p.A74V ENST00000314574 NM_005433.3 74 gCa/gTa 0 +ZNF761 UCSF GRCh37 19 53952869 53952869 + non_coding_transcript_exon_variant RNA SNP T T C NOVEL P25_Pri Untested WXS Illumina HiSeq 22 4 25 1 ENST00000454407.1:n.573T>C *191* ENST00000454407 0 +ZNF844 UCSF GRCh37 19 12186387 12186387 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Pri Untested WXS Illumina HiSeq 100 77 183 0 ENST00000439326.3:c.452G>T p.Arg151Ile p.R151I ENST00000439326 NM_001136501.1 151 aGa/aTa 0 +ADAM32 UCSF GRCh37 8 39007313 39007313 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 86 16 97 0 ENST00000379907.4:c.280C>G p.Gln94Glu p.Q94E ENST00000379907 NM_145004.5 94 Caa/Gaa 0 +ALB UCSF GRCh37 4 74280766 74280766 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 68 51 156 0 ENST00000295897.4:c.1073A>G p.Tyr358Cys p.Y358C ENST00000295897 NM_000477.5 358 tAt/tGt 0 +ALG8 UCSF GRCh37 11 77832193 77832193 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000299626.5:c.396delA p.Val133TrpfsTer24 p.V133Wfs*24 ENST00000299626 NM_024079.4 132 aaA/aa 0 +ALG8 UCSF GRCh37 11 77824924 77824971 + splice_donor_variant,coding_sequence_variant,intron_variant Splice_Site DEL AGGCTTACCAAGGCCAGGAAAGGACCCAATGAAAGAGCAGAAACTAAG AGGCTTACCAAGGCCAGGAAAGGACCCAATGAAAGAGCAGAAACTAAG GGCTTACCAAGGCCAGGAAAGGACCCAATGAAAGAGCAAAAACAAAA NOVEL P25_Rec Untested WXS Illumina HiSeq 11 0 ENST00000299626.5:c.738_777+8delinsTTTTGTTTTTGCTCTTTCATTGGGTCCTTTCCTGGCCTTGGTAAGCC p.X246_splice ENST00000299626 NM_024079.4 246 0 +ATRX UCSF GRCh37 X 76918873 76918874 + frameshift_variant,splice_region_variant Frame_Shift_Del DEL TT TT - NOVEL P25_Rec Untested WXS Illumina HiSeq 33 0 ENST00000373344.5:c.4117_4118del p.Lys1373GlyfsTer4 p.K1373Gfs*4 ENST00000373344 NM_000489.3 1373 AAg/g 0 +BAI3 UCSF GRCh37 6 69943256 69943257 + frameshift_variant Frame_Shift_Del DEL TA TA - NOVEL P25_Rec Untested WXS Illumina HiSeq 106 0 ENST00000370598.1:c.2556_2557del p.Cys853Ter p.C853* ENST00000370598 NM_001704.2 852 tTA/t 0 +BMPR2 UCSF GRCh37 2 203383749 203383752 + frameshift_variant Frame_Shift_Del DEL TTGC TTGC - NOVEL P25_Rec Untested WXS Illumina HiSeq 79 0 ENST00000374580.4:c.829_832del p.Leu277Ter p.L277* ENST00000374580 NM_001204.6 276 TTGCtt/tt 0 +CACNA1H UCSF GRCh37 16 1270131 1270131 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 252 28 285 0 ENST00000348261.5:c.6199G>A p.Val2067Ile p.V2067I ENST00000348261 NM_021098.2 2067 Gtc/Atc 0 +CCDC114 UCSF GRCh37 19 48800560 48800561 + frameshift_variant Frame_Shift_Del DEL AA AA - NOVEL P25_Rec Untested WXS Illumina HiSeq 57 0 ENST00000315396.7:c.1685_1686del p.Phe562TrpfsTer18 p.F562Wfs*18 ENST00000315396 NM_144577.3 562 tTT/t 0 +CCNA1 UCSF GRCh37 13 37007335 37007335 + stop_gained Nonsense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 41 13 110 0 ENST00000255465.4:c.274C>T p.Gln92Ter p.Q92* ENST00000255465 92 Cag/Tag 0 +CCNB1 UCSF GRCh37 5 68464167 68464167 + synonymous_variant Silent SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 157 40 189 0 ENST00000256442.5:c.360T>C p.Ile120= p.I120= ENST00000256442 NM_031966.3 120 atT/atC 0 +CCND1 UCSF GRCh37 11 69458623 69458623 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec somatic WXS Sanger Illumina HiSeq 544 420 87 0 ENST00000227507.2:c.438C>G p.Asn146Lys p.N146K ENST00000227507 NM_053056.2 146 aaC/aaG 0 +CD93 UCSF GRCh37 20 23065795 23065795 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 137 77 299 0 ENST00000246006.4:c.1035C>T p.Asp345= p.D345= ENST00000246006 NM_012072.3 345 gaC/gaT 0 +CDH17 UCSF GRCh37 8 95201472 95201472 + synonymous_variant Silent SNP C C A NOVEL P25_Rec Untested WXS Illumina HiSeq 200 108 293 1 ENST00000027335.3:c.93G>T p.Leu31= p.L31= ENST00000027335 NM_004063.3 31 ctG/ctT 0 +CLSPN UCSF GRCh37 1 36215290 36215290 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 106 25 142 0 ENST00000318121.3:c.2151G>C p.Lys717Asn p.K717N ENST00000318121 NM_022111.3 717 aaG/aaC 0 +CNGA3 UCSF GRCh37 2 99013128 99013128 + stop_gained Nonsense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 86 13 109 0 ENST00000272602.2:c.1495C>T p.Arg499Ter p.R499* ENST00000272602 499 Cga/Tga 0 +CNTLN UCSF GRCh37 9 17462971 17462973 + inframe_deletion In_Frame_Del DEL CTC CTC - NOVEL P25_Rec Untested WXS Illumina HiSeq 43 0 ENST00000380647.3:c.3366_3368del p.Leu1123del p.L1123del ENST00000380647 1122 CTC/- 0 +COL17A1 UCSF GRCh37 10 105815696 105815696 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 38 191 362 0 ENST00000353479.5:c.1531C>T p.Pro511Ser p.P511S ENST00000353479 NM_000494.3 511 Ccc/Tcc 0 +COL4A4 UCSF GRCh37 2 227920746 227920746 + synonymous_variant Silent SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 80 28 150 0 ENST00000396625.3:c.2631G>A p.Arg877= p.R877= ENST00000396625 NM_000092.4 877 cgG/cgA 0 +COL4A5 UCSF GRCh37 X 107846253 107846253 + stop_gained Nonsense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 59 42 103 0 ENST00000361603.2:c.2206G>T p.Glu736Ter p.E736* ENST00000361603 NM_000495.4 736 Gaa/Taa 0 +COL5A1 UCSF GRCh37 9 137703350 137703350 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 342 38 393 1 ENST00000371817.3:c.3595G>A p.Glu1199Lys p.E1199K ENST00000371817 NM_001278074.1 1199 Gag/Aag 0 +CPEB1 UCSF GRCh37 15 83226697 83226697 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 86 68 171 0 ENST00000568128.1:c.419G>A p.Gly140Glu p.G140E ENST00000568128 NM_030594.3 140 gGa/gAa 0 +DDX28 UCSF GRCh37 16 68055853 68055853 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 305 230 440 0 ENST00000332395.5:c.1253A>G p.Asp418Gly p.D418G ENST00000332395 NM_018380.3 418 gAt/gGt 0 +DNAJC21 UCSF GRCh37 5 34950377 34950377 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 57 12 79 0 ENST00000342382.4:c.1288A>G p.Ser430Gly p.S430G ENST00000342382 430 Agt/Ggt 0 +ESM1 UCSF GRCh37 5 54275251 54275252 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P25_Rec Untested WXS Illumina HiSeq 177 0 ENST00000381405.4:c.464dup p.Ser156IlefsTer66 p.S156Ifs*66 ENST00000381405 NM_007036.4 155 gca/gCca 0 +FAM169B UCSF GRCh37 15 98995135 98995135 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 61 14 86 0 ENST00000558256.1:c.289C>A p.Leu97Met p.L97M ENST00000558256 NM_182562.2 97 Ctg/Atg 0 +FAM47C UCSF GRCh37 X 37027335 37027335 + synonymous_variant Silent SNP A A T NOVEL P25_Rec Untested WXS Illumina HiSeq 68 50 123 0 ENST00000358047.3:c.852A>T p.Pro284= p.P284= ENST00000358047 NM_001013736.2 284 ccA/ccT 0 +FSIP2 UCSF GRCh37 2 186697826 186697826 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 104 71 223 0 ENST00000424728.1:c.20597A>G p.Lys6866Arg p.K6866R ENST00000424728 6866 aAg/aGg 0 +GNAS UCSF GRCh37 20 57429313 57429313 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 303 47 311 0 ENST00000371100.4:c.993G>A p.Ala331= p.A331= ENST00000371100 NM_001077490.1 331 gcG/gcA 0 +GSDMD UCSF GRCh37 8 144641513 144641513 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 94 103 146 0 ENST00000262580.4:c.8C>T p.Ser3Leu p.S3L ENST00000262580 NM_024736.6 3 tCg/tTg 0 +HIVEP2 UCSF GRCh37 6 143092015 143092015 + synonymous_variant Silent SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 285 241 810 0 ENST00000012134.2:c.3861G>C p.Gly1287= p.G1287= ENST00000012134 1287 ggG/ggC 0 +HMG20A UCSF GRCh37 15 77770709 77770709 + missense_variant Missense_Mutation SNP A A T NOVEL P25_Rec Untested WXS Illumina HiSeq 129 17 106 0 ENST00000336216.4:c.764A>T p.Lys255Met p.K255M ENST00000336216 255 aAg/aTg 0 +HMG20B UCSF GRCh37 19 3576984 3576984 + synonymous_variant Silent SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 64 19 82 0 ENST00000333651.6:c.687C>T p.Ser229= p.S229= ENST00000333651 NM_006339.2 229 agC/agT 0 +HRASLS2 UCSF GRCh37 11 63320450 63320450 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0030 P25_Rec Untested WXS Illumina HiSeq 163 23 377 0 ENST00000255695.1:c.475C>T p.Arg159Trp p.R159W ENST00000255695 NM_017878.1 159 Cgg/Tgg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 8 8 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL7R UCSF GRCh37 5 35875666 35875666 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 98 24 134 0 ENST00000303115.3:c.853C>T p.His285Tyr p.H285Y ENST00000303115 NM_002185.3 285 Cat/Tat 0 +INHBA UCSF GRCh37 7 41729606 41729606 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 345 103 528 0 ENST00000242208.4:c.923G>A p.Arg308His p.R308H ENST00000242208 NM_002192.2 308 cGt/cAt 0 +INTS4 UCSF GRCh37 11 77672161 77672189 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region INS ACCATGAGACGTATCTGTCAGATGCTATT ACCATGAGACGTATCTGTCAGATGCTATT CCCAAGAGACGTATCTTTCAAATGCTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 7 0 ENST00000534064.1:c.472-5_495delinsTAATAGCATTTGAAAGATACGTCTCTTGGG p.X158_splice ENST00000534064 NM_033547.3 0 +INTS4 UCSF GRCh37 11 77672148 77672189 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region INS ACTTATTTCTTACACCATGAGACGTATCTGTCAGATGCTATT ACTTATTTCTTACACCATGAGACGTATCTGTCAGATGCTATT CCTTTTTTTTTTCACCATGAGACGTATTTTTCAGAAGCTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 9 0 ENST00000534064.1:c.472-5_508delinsTAATAGCTTCTGAAAAATACGTCTCATGGTGAAAAAAAAAAGG p.X158_splice ENST00000534064 NM_033547.3 0 +INTS4 UCSF GRCh37 11 77672152 77672189 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS ATTTCTTACACCATGAGACGTATCTGTCAGATGCTATT ATTTCTTACACCATGAGACGTATCTGTCAGATGCTATT TTTTTTTTCACCATAAGACGTATCTTTCAAATGTTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 17 0 ENST00000534064.1:c.472-5_504delinsTAATAACATTTGAAAGATACGTCTTATGGTGAAAAAAAA p.X158_splice ENST00000534064 NM_033547.3 0 +INTS4 UCSF GRCh37 11 77672175 77672189 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS CTGTCAGATGCTATT CTGTCAGATGCTATT ATTTCAGATGTTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 7 0 ENST00000534064.1:c.472-5_481delinsTAATAACATCTGAAAT p.X158_splice ENST00000534064 NM_033547.3 0 +INTS4 UCSF GRCh37 11 77672165 77672189 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS TGAGACGTATCTGTCAGATGCTATT TGAGACGTATCTGTCAGATGCTATT AGAAAAGTTTTTTTAAAAAGTTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 7 0 ENST00000534064.1:c.472-5_491delinsTAATAACTTTTTAAAAAAACTTTTCT p.X158_splice ENST00000534064 NM_033547.3 0 +ITGA2 UCSF GRCh37 5 52385787 52385787 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 220 27 231 0 ENST00000296585.5:c.3360G>A p.Met1120Ile p.M1120I ENST00000296585 NM_002203.3 1120 atG/atA 0 +KLHDC4 UCSF GRCh37 16 87744934 87744934 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 318 38 355 0 ENST00000270583.5:c.951C>T p.Asp317= p.D317= ENST00000270583 NM_017566.3 317 gaC/gaT 0 +KRT75 UCSF GRCh37 12 52825420 52825420 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 116 91 202 0 ENST00000252245.5:c.777C>T p.Asp259= p.D259= ENST00000252245 NM_004693.2 259 gaC/gaT 0 +KRT82 UCSF GRCh37 12 52793852 52793852 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.010,1000g2011may_all_0.0015,snp132_rs61730589 P25_Rec Untested WXS Illumina HiSeq 86 20 97 0 ENST00000257974.2:c.859G>A p.Gly287Ser p.G287S ENST00000257974 NM_033033.3 287 Ggc/Agc 0 +LLGL2 UCSF GRCh37 17 73569328 73569328 + synonymous_variant Silent SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 78 23 59 0 ENST00000392550.3:c.2694C>T p.Ile898= p.I898= ENST00000392550 NM_001031803.1 898 atC/atT 0 +LONRF1 UCSF GRCh37 8 12612285 12612285 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 25 30 76 0 ENST00000398246.3:c.645C>T p.Ala215= p.A215= ENST00000398246 NM_152271.3 215 gcC/gcT 0 +MARS UCSF GRCh37 12 57883053 57883053 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P25_Rec Untested WXS Illumina HiSeq 13 0 ENST00000262027.5:c.212del p.Leu71CysfsTer33 p.L71Cfs*33 ENST00000262027 NM_004990.3 68 taT/ta 0 +MARS UCSF GRCh37 12 57882776 57882808 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TAACCCATTTTCCATTCTTGCATCAGATTGTGT TAACCCATTTTCCATTCTTGCATCAGATTGTGT AACCCATTTTCCATTCTTGCATCAGATTTTGG NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000262027.5:c.110-26_116delinsAACCCATTTTCCATTCTTGCATCAGATTTTGG p.X37_splice ENST00000262027 NM_004990.3 0 +MFSD7 UCSF GRCh37 4 680052 680052 + missense_variant Missense_Mutation SNP G G C NOVEL P25_Rec Untested WXS Illumina HiSeq 72 17 58 0 ENST00000404286.2:c.334C>G p.Leu112Val p.L112V ENST00000404286 NM_032219.2 112 Cta/Gta 0 +MFSD7 UCSF GRCh37 4 679684 679684 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 458 120 294 0 ENST00000404286.2:c.525C>T p.Val175= p.V175= ENST00000404286 NM_032219.2 175 gtC/gtT 0 +MORC4 UCSF GRCh37 X 106185751 106185751 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 129 99 218 0 ENST00000355610.4:c.2370G>C p.Gln790His p.Q790H ENST00000355610 NM_001085354.2 790 caG/caC 0 +MUC16 UCSF GRCh37 19 9065233 9065233 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 99 72 162 1 ENST00000397910.4:c.22213T>C p.Ser7405Pro p.S7405P ENST00000397910 NM_024690.2 7405 Tct/Cct 0 +MYCN UCSF GRCh37 2 16082314 16082315 + frameshift_variant Frame_Shift_Ins INS - - C NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000281043.3:c.134dup p.Glu47GlyfsTer8 p.E47Gfs*8 ENST00000281043 NM_005378.4 43 acc/acCc 0 +MYEOV UCSF GRCh37 11 69063724 69063724 + frameshift_variant Frame_Shift_Del DEL G G - 1000g2010nov_all P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000308946.3:c.813delG p.Trp272GlyfsTer66 p.W272Gfs*66 ENST00000308946 NM_138768.2 269 ctG/ct 0 +MYH14 UCSF GRCh37 19 50780049 50780049 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 57 11 67 0 ENST00000376970.2:c.3692A>G p.Lys1231Arg p.K1231R ENST00000376970 NM_024729.3 1231 aAg/aGg 0 +NAGS UCSF GRCh37 17 42084844 42084844 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 84 39 72 0 ENST00000293404.3:c.1250C>T p.Ser417Phe p.S417F ENST00000293404 NM_153006.2 417 tCc/tTc 0 +NBPF1 UCSF GRCh37 1 16893721 16893721 + missense_variant Missense_Mutation SNP A A C 1000g2010nov_all_0.064 P25_Rec Untested WXS Illumina HiSeq 10 5 13 0 ENST00000430580.2:c.2792T>G p.Phe931Cys p.F931C ENST00000430580 NM_017940.4 931 tTt/tGt 0 +NLRP9 UCSF GRCh37 19 56243414 56243414 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 50 39 118 0 ENST00000332836.2:c.1783C>T p.Arg595Cys p.R595C ENST00000332836 NM_176820.2 595 Cgc/Tgc 0 +NOTCH4 UCSF GRCh37 6 32169238 32169238 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 235 106 222 0 ENST00000375023.3:c.3795C>T p.Asn1265= p.N1265= ENST00000375023 NM_004557.3 1265 aaC/aaT 0 +NRP2 UCSF GRCh37 2 206605343 206605345 + inframe_deletion In_Frame_Del DEL CAG CAG - NOVEL P25_Rec Untested WXS Illumina HiSeq 10 0 ENST00000360409.3:c.1247_1249del p.Ser416_Gly417delinsCys p.S416_G417delinsC ENST00000360409 NM_003872.2 416 tCAGgt/tgt 0 +NXF1 UCSF GRCh37 11 62564841 62564841 + synonymous_variant Silent SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 7 31 52 0 ENST00000294172.2:c.1071C>A p.Pro357= p.P357= ENST00000294172 NM_006362.4 357 ccC/ccA 0 +OGFR UCSF GRCh37 20 61441865 61441865 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 97 74 134 0 ENST00000290291.6:c.413G>A p.Arg138Gln p.R138Q ENST00000290291 NM_007346.2 138 cGa/cAa 0 +OR2A5 UCSF GRCh37 7 143747979 143747979 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 132 56 285 0 ENST00000408906.2:c.485T>C p.Leu162Pro p.L162P ENST00000408906 NM_012365.1 162 cTc/cCc 0 +OR4S2 UCSF GRCh37 11 55419231 55419231 + synonymous_variant Silent SNP T T A NOVEL P25_Rec Untested WXS Illumina HiSeq 71 55 285 0 ENST00000312422.2:c.852T>A p.Ile284= p.I284= ENST00000312422 NM_001004059.2 284 atT/atA 0 +OR52A5 UCSF GRCh37 11 5153593 5153593 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 177 149 573 0 ENST00000307388.1:c.280A>G p.Ile94Val p.I94V ENST00000307388 NM_001005160.2 94 Att/Gtt 0 +OR6C6 UCSF GRCh37 12 55688653 55688653 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 148 33 196 0 ENST00000358433.2:c.364G>A p.Val122Ile p.V122I ENST00000358433 NM_001005493.1 122 Gtt/Att 0 +PDE6B UCSF GRCh37 4 659088 659088 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 96 22 75 0 ENST00000496514.1:c.2238G>A p.Leu746= p.L746= ENST00000496514 746 ttG/ttA 0 +PGLYRP3 UCSF GRCh37 1 153279615 153279615 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 79 26 81 0 ENST00000290722.1:c.184G>A p.Val62Ile p.V62I ENST00000290722 NM_052891.1 62 Gtt/Att 0 +PGR UCSF GRCh37 11 100996839 100996839 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 48 24 176 0 ENST00000325455.5:c.1688C>T p.Pro563Leu p.P563L ENST00000325455 NM_001202474.3 563 cCt/cTt 0 +PIGR UCSF GRCh37 1 207105892 207105892 + synonymous_variant Silent SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 59 26 107 0 ENST00000356495.4:c.1917G>A p.Ala639= p.A639= ENST00000356495 NM_002644.3 639 gcG/gcA 0 +PLA2G4A UCSF GRCh37 1 186909194 186909194 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 364 113 469 0 ENST00000367466.3:c.1001T>C p.Val334Ala p.V334A ENST00000367466 NM_024420.2 334 gTc/gCc 0 +PLEKHG1 UCSF GRCh37 6 151161729 151161731 + inframe_deletion In_Frame_Del DEL AGA AGA - NOVEL P25_Rec Untested WXS Illumina HiSeq 47 0 ENST00000358517.2:c.3861_3863del p.Glu1287del p.E1287del ENST00000358517 1285 tcAGAa/tca 0 +PLEKHG6 UCSF GRCh37 12 6436644 6436644 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 68 46 96 0 ENST00000011684.7:c.1895G>A p.Arg632His p.R632H ENST00000011684 NM_018173.3 632 cGt/cAt 0 +PRSS21 UCSF GRCh37 16 2867889 2867889 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 46 6 47 0 ENST00000005995.3:c.179G>A p.Arg60His p.R60H ENST00000005995 60 cGc/cAc 0 +QRICH2 UCSF GRCh37 17 74288509 74288510 + inframe_insertion In_Frame_Ins INS - - CTGCACCAGGTTGGACCAAACCACGCTGAT NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000262765.5:c.1800_1801insATCAGCGTGGTTTGGTCCAACCTGGTGCAG p.Ala600_Asp601insIleSerValValTrpSerAsnLeuValGln p.A600_D601insISVVWSNLVQ ENST00000262765 NM_032134.1 600 -/ATCAGCGTGGTTTGGTCCAACCTGGTGCAG 0 +RPH3A UCSF GRCh37 12 113314503 113314503 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 63 11 69 0 ENST00000389385.4:c.1003G>A p.Gly335Arg p.G335R ENST00000389385 NM_001143854.1 335 Gga/Aga 0 +SCAND3 UCSF GRCh37 6 28543477 28543477 + missense_variant Missense_Mutation SNP C C A NOVEL P25_Rec Untested WXS Illumina HiSeq 499 78 490 0 ENST00000452236.2:c.1005G>T p.Lys335Asn p.K335N ENST00000452236 NM_052923.1 335 aaG/aaT 0 +SEC63 UCSF GRCh37 6 108214774 108214774 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000369002.4:c.1586del p.Lys529ArgfsTer4 p.K529Rfs*4 ENST00000369002 NM_007214.4 529 aAg/ag 0 +SEMA3B UCSF GRCh37 3 50310793 50310795 + intron_variant,non_coding_transcript_variant Intron DEL CTT CTT - NOVEL P25_Rec Untested WXS Illumina HiSeq 84 0 ENST00000456210.1:n.158+54_158+56delCTT *53* ENST00000456210 0 +SEMA6D UCSF GRCh37 15 48058784 48058784 + intron_variant Intron SNP G G C NOVEL P25_Rec Untested WXS Illumina HiSeq 128 30 174 0 ENST00000316364.5:c.1647-29G>C *549* ENST00000316364 NM_153618.1 0 +SIN3B UCSF GRCh37 19 16976309 16976311 + inframe_deletion In_Frame_Del DEL AGG AGG - NOVEL P25_Rec Untested WXS Illumina HiSeq 9 0 ENST00000379803.1:c.1570_1572del p.Glu524del p.E524del ENST00000379803 NM_015260.2 523 cAGGag/cag 0 +SLC23A2 UCSF GRCh37 20 4850569 4850570 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P25_Rec Untested WXS Illumina HiSeq 13 0 ENST00000338244.1:c.1233dup p.Ile412HisfsTer18 p.I412Hfs*18 ENST00000338244 NM_005116.5 411 ccc/ccCc 0 +SLC26A9 UCSF GRCh37 1 205899074 205899074 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 59 14 80 0 ENST00000367135.3:c.663G>C p.Lys221Asn p.K221N ENST00000367135 NM_052934.3 221 aaG/aaC 0 +SLC6A3 UCSF GRCh37 5 1422076 1422076 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 122 28 141 0 ENST00000270349.9:c.707C>T p.Pro236Leu p.P236L ENST00000270349 NM_001044.4 236 cCg/cTg 0 +SLIT3 UCSF GRCh37 5 168093656 168093656 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 46 40 154 0 ENST00000519560.1:c.4375C>T p.Arg1459Cys p.R1459C ENST00000519560 NM_003062.3 1459 Cgc/Tgc 0 +SPATS2L UCSF GRCh37 2 201303884 201303884 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 147 52 216 0 ENST00000358677.5:c.485G>A p.Gly162Glu p.G162E ENST00000358677 NM_015535.2 162 gGg/gAg 0 +SPEN UCSF GRCh37 1 16257644 16257644 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 258 134 237 0 ENST00000375759.3:c.4909G>A p.Val1637Ile p.V1637I ENST00000375759 NM_015001.2 1637 Gtt/Att 0 +STXBP5 UCSF GRCh37 6 147648347 147648347 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 34 18 94 0 ENST00000321680.6:c.2015A>G p.Tyr672Cys p.Y672C ENST00000321680 NM_001127715.2 672 tAt/tGt 0 +TGM3 UCSF GRCh37 20 2312794 2312794 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 119 51 228 0 ENST00000381458.5:c.1480G>T p.Ala494Ser p.A494S ENST00000381458 NM_003245.3 494 Gca/Tca 0 +TRPV5 UCSF GRCh37 7 142606703 142606703 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 23 6 47 0 ENST00000265310.1:c.1848C>T p.Ser616= p.S616= ENST00000265310 NM_019841.4 616 tcC/tcT 0 +UACA UCSF GRCh37 15 70959163 70959163 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 334 46 424 1 ENST00000322954.6:c.3860A>G p.Lys1287Arg p.K1287R ENST00000322954 NM_018003.2 1287 aAg/aGg 0 +USP35 UCSF GRCh37 11 77920720 77920722 + inframe_deletion In_Frame_Del DEL CGC CGC - NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000529308.1:c.1829_1831del p.Arg610del p.R610del ENST00000529308 NM_020798.2 607 CGC/- 0 +VPS35 UCSF GRCh37 16 46706301 46706301 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 227 195 360 0 ENST00000299138.7:c.1244T>C p.Val415Ala p.V415A ENST00000299138 NM_018206.4 415 gTc/gCc 0 +WDR49 UCSF GRCh37 3 167249025 167249025 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 63 12 105 0 ENST00000308378.3:c.1040C>A p.Pro347His p.P347H ENST00000308378 NM_178824.3 347 cCc/cAc 0 +WIF1 UCSF GRCh37 12 65514908 65514908 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 15 3 25 0 ENST00000286574.4:c.64C>A p.Leu22Met p.L22M ENST00000286574 NM_007191.4 22 Ctg/Atg 0 +WRAP53 UCSF GRCh37 17 7592209 7592210 + frameshift_variant Frame_Shift_Del DEL AG AG - NOVEL P25_Rec Untested WXS Illumina HiSeq 70 0 ENST00000316024.5:c.245_246del p.Glu82ValfsTer5 p.E82Vfs*5 ENST00000316024 81 acAGag/acag 0 +YARS UCSF GRCh37 1 33245060 33245060 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 293 159 343 0 ENST00000373477.4:c.1399G>A p.Val467Met p.V467M ENST00000373477 NM_003680.3 467 Gtg/Atg 0 +YES1 UCSF GRCh37 18 756607 756607 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 86 73 138 0 ENST00000314574.4:c.221C>T p.Ala74Val p.A74V ENST00000314574 NM_005433.3 74 gCa/gTa 0 +ZDBF2 UCSF GRCh37 2 207176038 207176038 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 150 50 243 0 ENST00000374423.3:c.6786G>A p.Ala2262= p.A2262= ENST00000374423 NM_020923.1 2262 gcG/gcA 0 +ZMYM6 UCSF GRCh37 1 35496163 35496165 + inframe_deletion In_Frame_Del DEL TTC TTC - NOVEL P25_Rec Untested WXS Illumina HiSeq 22 0 ENST00000357182.4:c.76_78del p.Glu26del p.E26del ENST00000357182 NM_007167.3 26 GAA/- 0 +ZNF202 UCSF GRCh37 11 123596991 123596991 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 256 38 512 0 ENST00000336139.4:c.1661C>T p.Ala554Val p.A554V ENST00000336139 554 gCg/gTg 0 +ZNF208 UCSF GRCh37 19 22157024 22157024 + missense_variant Missense_Mutation SNP A A T NOVEL P25_Rec Untested WXS Illumina HiSeq 24 6 23 0 ENST00000397126.4:c.812T>A p.Ile271Asn p.I271N ENST00000397126 NM_007153.3 271 aTc/aAc 0 +ZNF844 UCSF GRCh37 19 12186387 12186387 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 116 94 183 0 ENST00000439326.3:c.452G>T p.Arg151Ile p.R151I ENST00000439326 NM_001136501.1 151 aGa/aTa 0 +ZNF90 UCSF GRCh37 19 20228765 20228765 + missense_variant Missense_Mutation SNP C C A NOVEL P25_Rec Untested WXS Illumina HiSeq 154 41 222 0 ENST00000418063.2:c.402C>A p.Asn134Lys p.N134K ENST00000418063 NM_007138.1 134 aaC/aaA 0 +ANK3 UCSF GRCh37 10 61946630 61946630 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 42 29 101 0 ENST00000280772.2:c.1928A>G p.Gln643Arg p.Q643R ENST00000280772 NM_020987.3 643 cAg/cGg 0 +ANKRD30B UCSF GRCh37 18 14851953 14851953 + missense_variant Missense_Mutation SNP A A T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 33 5 56 0 ENST00000358984.4:c.3653A>T p.Asp1218Val p.D1218V ENST00000358984 NM_001145029.1 1218 gAt/gTt 0 +ATRX UCSF GRCh37 X 76909677 76909681 + frameshift_variant Frame_Shift_Del DEL CTTTC CTTTC - NOVEL P26_Pri_A Untested WXS Illumina HiSeq 73 0 ENST00000373344.5:c.4224_4228del p.Lys1408AsnfsTer11 p.K1408Nfs*11 ENST00000373344 NM_000489.3 1408 aaGAAAGca/aaca 0 +CHD4 UCSF GRCh37 12 6692539 6692539 + synonymous_variant Silent SNP T T C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 27 28 49 0 ENST00000357008.2:c.3885A>G p.Glu1295= p.E1295= ENST00000357008 NM_001273.2 1295 gaA/gaG 0 +EMR3 UCSF GRCh37 19 14748981 14748981 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 98 57 163 0 ENST00000253673.5:c.1420G>A p.Val474Ile p.V474I ENST00000253673 NM_032571.3 474 Gtt/Att 0 +EYS UCSF GRCh37 6 66112482 66112482 + missense_variant Missense_Mutation SNP C C G NOVEL P26_Pri_A Untested WXS Illumina HiSeq 84 54 138 0 ENST00000370616.2:c.1073G>C p.Cys358Ser p.C358S ENST00000370616 358 tGt/tCt 0 +FGFR4 UCSF GRCh37 5 176522719 176522719 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 29 20 36 0 ENST00000292408.4:c.1816C>T p.Arg606Trp p.R606W ENST00000292408 NM_213647.1 606 Cgg/Tgg 0 +GAD1 UCSF GRCh37 2 171700560 171700565 + inframe_deletion In_Frame_Del DEL CATATG CATATG - NOVEL P26_Pri_A Untested WXS Illumina HiSeq 73 0 ENST00000358196.3:c.644_649del p.Thr215_Glu217delinsLys p.T215_E217delinsK ENST00000358196 NM_000817.2 215 aCATATGaa/aaa 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 13 16 27 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGHMBP2 UCSF GRCh37 11 68707014 68707014 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 8 12 25 0 ENST00000255078.3:c.2797G>A p.Gly933Ser p.G933S ENST00000255078 NM_002180.2 933 Ggt/Agt 0 +KIF26B UCSF GRCh37 1 245848890 245848890 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 91 66 164 0 ENST00000407071.2:c.2605G>A p.Gly869Arg p.G869R ENST00000407071 NM_018012.3 869 Ggg/Agg 0 +MED12 UCSF GRCh37 X 70357661 70357661 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 164 117 283 0 ENST00000374080.3:c.5912A>C p.Gln1971Pro p.Q1971P ENST00000374080 1971 cAg/cCg 0 +MURC UCSF GRCh37 9 103348678 103348678 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Pri_A Untested WXS Illumina HiSeq 190 49 156 0 ENST00000307584.5:c.1040A>G p.Gln347Arg p.Q347R ENST00000307584 NM_001018116.2 347 cAg/cGg 0 +NCOA6 UCSF GRCh37 20 33338237 33338237 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 43 43 94 0 ENST00000359003.2:c.1761T>G p.Ile587Met p.I587M ENST00000359003 NM_014071.3 587 atT/atG 0 +PCDHB2 UCSF GRCh37 5 140475862 140475862 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0149,snp132_rs61745643 P26_Pri_A Untested WXS Illumina HiSeq 22 4 28 1 ENST00000194155.4:c.1488G>A p.Gln496= p.Q496= ENST00000194155 NM_018936.2 496 caG/caA 0 +PGGT1B UCSF GRCh37 5 114552629 114552629 + missense_variant Missense_Mutation SNP T T A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 14 17 25 0 ENST00000419445.1:c.885A>T p.Arg295Ser p.R295S ENST00000419445 NM_005023.3 295 agA/agT 0 +RBMX UCSF GRCh37 X 135958696 135958696 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.08188,snp132_rs112800567 P26_Pri_A Untested WXS Illumina HiSeq 19 6 20 1 ENST00000320676.7:c.507A>G p.Gly169= p.G169= ENST00000320676 NM_002139.3 169 ggA/ggG 0 +RELN UCSF GRCh37 7 103138574 103138574 + synonymous_variant Silent SNP T T G NOVEL P26_Pri_A Untested WXS Illumina HiSeq 114 38 153 0 ENST00000428762.1:c.8793A>C p.Gly2931= p.G2931= ENST00000428762 NM_005045.3 2931 ggA/ggC 0 +RETSAT UCSF GRCh37 2 85570849 85570849 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.169,snp132_rs28418594 P26_Pri_A Untested WXS Illumina HiSeq 12 4 17 0 ENST00000295802.4:c.1606G>A p.Gly536Arg p.G536R ENST00000295802 NM_017750.3 536 Ggg/Agg 0 +SCN9A UCSF GRCh37 2 167056179 167056179 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Pri_A Untested WXS Illumina HiSeq 49 35 92 0 ENST00000303354.6:c.4973T>C p.Ile1658Thr p.I1658T ENST00000303354 1658 aTc/aCc 0 +SFI1 UCSF GRCh37 22 32014359 32014359 + synonymous_variant Silent SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 39 43 70 0 ENST00000400288.2:c.3684C>T p.Gly1228= p.G1228= ENST00000400288 NM_001007467.2 1228 ggC/ggT 0 +SLC38A8 UCSF GRCh37 16 84050190 84050190 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 28 26 43 1 ENST00000299709.3:c.1096C>T p.Pro366Ser p.P366S ENST00000299709 NM_001080442.1 366 Cct/Tct 0 +SPP1 UCSF GRCh37 4 88903874 88903875 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P26_Pri_A Untested WXS Illumina HiSeq 73 0 ENST00000395080.3:c.771_772del p.Ser258ArgfsTer4 p.S258Rfs*4 ENST00000395080 NM_001040058.1 257 caTTcc/cacc 0 +TBC1D5 UCSF GRCh37 3 17279718 17279718 + stop_gained Nonsense_Mutation SNP G G A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 189 134 261 0 ENST00000253692.7:c.1525C>T p.Gln509Ter p.Q509* ENST00000253692 NM_014744.2 509 Caa/Taa 0 +TIAM1 UCSF GRCh37 21 32639259 32639259 + synonymous_variant Silent SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 36 16 68 0 ENST00000286827.3:c.30G>A p.Glu10= p.E10= ENST00000286827 NM_003253.2 10 gaG/gaA 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 6 67 73 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +XPO7 UCSF GRCh37 8 21862569 21862569 + synonymous_variant Silent SNP T T C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 240 181 396 1 ENST00000252512.9:c.3234T>C p.Tyr1078= p.Y1078= ENST00000252512 NM_015024.4 1078 taT/taC 0 +AIM2 UCSF GRCh37 1 159032487 159032487 + frameshift_variant Frame_Shift_Del DEL T T - 1000g2010nov_all P26_Pri_B Untested WXS Illumina HiSeq 6 0 ENST00000368130.4:c.1027delA p.Thr343HisfsTer14 p.T343Hfs*14 ENST00000368130 NM_004833.1 343 Aca/ca 0 +ANK3 UCSF GRCh37 10 61946630 61946630 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 27 21 101 0 ENST00000280772.2:c.1928A>G p.Gln643Arg p.Q643R ENST00000280772 NM_020987.3 643 cAg/cGg 0 +ATRX UCSF GRCh37 X 76909677 76909681 + frameshift_variant Frame_Shift_Del DEL CTTTC CTTTC - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 85 0 ENST00000373344.5:c.4224_4228del p.Lys1408AsnfsTer11 p.K1408Nfs*11 ENST00000373344 NM_000489.3 1408 aaGAAAGca/aaca 0 +C20orf96(NM_080571:exon2:c.17+2->TA) UCSF GRCh37 20 271226 271227 + splice_region_variant,intron_variant Splice_Region INS - - TA NOVEL P26_Pri_B Untested WXS Illumina HiSeq 11 0 ENST00000360321.2:c.20+6_20+7dup p.X7_splice ENST00000360321 NM_153269.2 0 +CDC27 UCSF GRCh37 17 45234707 45234707 + missense_variant Missense_Mutation SNP T T A 1000g2010nov_all_0.209,snp132_rs75353677 P26_Pri_B Untested WXS Illumina HiSeq 44 7 47 1 ENST00000066544.3:c.519A>T p.Leu173Phe p.L173F ENST00000066544 NM_001256.3 173 ttA/ttT 0 +CHD4 UCSF GRCh37 12 6692539 6692539 + synonymous_variant Silent SNP T T C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 22 16 49 0 ENST00000357008.2:c.3885A>G p.Glu1295= p.E1295= ENST00000357008 NM_001273.2 1295 gaA/gaG 0 +EMR3 UCSF GRCh37 19 14748981 14748981 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 71 48 163 0 ENST00000253673.5:c.1420G>A p.Val474Ile p.V474I ENST00000253673 NM_032571.3 474 Gtt/Att 0 +EYS UCSF GRCh37 6 66112482 66112482 + missense_variant Missense_Mutation SNP C C G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 81 48 138 0 ENST00000370616.2:c.1073G>C p.Cys358Ser p.C358S ENST00000370616 358 tGt/tCt 0 +FGFR4 UCSF GRCh37 5 176522719 176522719 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 11 6 36 0 ENST00000292408.4:c.1816C>T p.Arg606Trp p.R606W ENST00000292408 NM_213647.1 606 Cgg/Tgg 0 +GAD1 UCSF GRCh37 2 171700560 171700565 + inframe_deletion In_Frame_Del DEL CATATG CATATG - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 55 0 ENST00000358196.3:c.644_649del p.Thr215_Glu217delinsLys p.T215_E217delinsK ENST00000358196 NM_000817.2 215 aCATATGaa/aaa 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 13 10 27 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGHMBP2 UCSF GRCh37 11 68707014 68707014 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 13 9 25 0 ENST00000255078.3:c.2797G>A p.Gly933Ser p.G933S ENST00000255078 NM_002180.2 933 Ggt/Agt 0 +KIF26B UCSF GRCh37 1 245848890 245848890 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 82 47 164 0 ENST00000407071.2:c.2605G>A p.Gly869Arg p.G869R ENST00000407071 NM_018012.3 869 Ggg/Agg 0 +MED12 UCSF GRCh37 X 70357661 70357661 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 82 71 283 0 ENST00000374080.3:c.5912A>C p.Gln1971Pro p.Q1971P ENST00000374080 1971 cAg/cCg 0 +MURC UCSF GRCh37 9 103348678 103348678 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 159 56 156 0 ENST00000307584.5:c.1040A>G p.Gln347Arg p.Q347R ENST00000307584 NM_001018116.2 347 cAg/cGg 0 +NCOA6 UCSF GRCh37 20 33338237 33338237 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 38 29 94 0 ENST00000359003.2:c.1761T>G p.Ile587Met p.I587M ENST00000359003 NM_014071.3 587 atT/atG 0 +NEUROD6 UCSF GRCh37 7 31378635 31378635 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 6 0 ENST00000297142.3:c.248delA p.Lys83ArgfsTer35 p.K83Rfs*35 ENST00000297142 NM_022728.3 83 aAg/ag 0 +PCNXL3 UCSF GRCh37 11 65383789 65383789 + missense_variant Missense_Mutation SNP T T G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 27 4 61 1 ENST00000355703.3:c.7T>G p.Ser3Ala p.S3A ENST00000355703 NM_032223.2 3 Tcg/Gcg 0 +PGGT1B UCSF GRCh37 5 114552629 114552629 + missense_variant Missense_Mutation SNP T T A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 16 8 25 0 ENST00000419445.1:c.885A>T p.Arg295Ser p.R295S ENST00000419445 NM_005023.3 295 agA/agT 0 +POPDC2 UCSF GRCh37 3 119378815 119378815 + synonymous_variant Silent SNP T T G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 16 10 38 0 ENST00000264231.3:c.456A>C p.Thr152= p.T152= ENST00000264231 NM_022135.2 152 acA/acC 0 +PRG4 UCSF GRCh37 1 186276052 186276052 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 37 6 71 1 ENST00000445192.2:c.1201A>C p.Thr401Pro p.T401P ENST00000445192 NM_005807.3 401 Acc/Ccc 0 +PRICKLE4 UCSF GRCh37 6 41754576 41754595 + downstream_gene_variant 3'Flank INS CGCTGCTGCCGGCGGTTCCA CGCTGCTGCCGGCGGTTCCA TCTCGCTGCTGCCGGCGGTTTCC NOVEL P26_Pri_B Untested WXS Illumina HiSeq 14 0 ENST00000359201 0 +RBM45 UCSF GRCh37 2 178988920 178988920 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 6 0 ENST00000286070.5:c.1143delA p.Ala382LeufsTer7 p.A382Lfs*7 ENST00000286070 NM_152945.2 379 Aaa/aa 0 +RELN UCSF GRCh37 7 103138574 103138574 + synonymous_variant Silent SNP T T G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 138 37 153 0 ENST00000428762.1:c.8793A>C p.Gly2931= p.G2931= ENST00000428762 NM_005045.3 2931 ggA/ggC 0 +SCN9A UCSF GRCh37 2 167056179 167056179 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 40 26 92 0 ENST00000303354.6:c.4973T>C p.Ile1658Thr p.I1658T ENST00000303354 1658 aTc/aCc 0 +SFI1 UCSF GRCh37 22 32014359 32014359 + synonymous_variant Silent SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 28 27 70 0 ENST00000400288.2:c.3684C>T p.Gly1228= p.G1228= ENST00000400288 NM_001007467.2 1228 ggC/ggT 0 +SLC38A8 UCSF GRCh37 16 84050190 84050190 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 35 18 43 1 ENST00000299709.3:c.1096C>T p.Pro366Ser p.P366S ENST00000299709 NM_001080442.1 366 Cct/Tct 0 +SPP1 UCSF GRCh37 4 88903874 88903875 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 92 0 ENST00000395080.3:c.771_772del p.Ser258ArgfsTer4 p.S258Rfs*4 ENST00000395080 NM_001040058.1 257 caTTcc/cacc 0 +TBC1D5 UCSF GRCh37 3 17279718 17279718 + stop_gained Nonsense_Mutation SNP G G A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 206 134 261 0 ENST00000253692.7:c.1525C>T p.Gln509Ter p.Q509* ENST00000253692 NM_014744.2 509 Caa/Taa 0 +TIAM1 UCSF GRCh37 21 32639259 32639259 + synonymous_variant Silent SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 38 20 68 0 ENST00000286827.3:c.30G>A p.Glu10= p.E10= ENST00000286827 NM_003253.2 10 gaG/gaA 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 11 44 73 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +XPO7 UCSF GRCh37 8 21862569 21862569 + synonymous_variant Silent SNP T T C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 262 191 396 1 ENST00000252512.9:c.3234T>C p.Tyr1078= p.Y1078= ENST00000252512 NM_015024.4 1078 taT/taC 0 +ANK3 UCSF GRCh37 10 61946630 61946630 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 56 43 101 0 ENST00000280772.2:c.1928A>G p.Gln643Arg p.Q643R ENST00000280772 NM_020987.3 643 cAg/cGg 0 +ATN1 UCSF GRCh37 12 7044946 7044946 + synonymous_variant Silent SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 667 180 581 0 ENST00000356654.4:c.516A>G p.Pro172= p.P172= ENST00000356654 NM_001007026.1 172 ccA/ccG 0 +ATRX UCSF GRCh37 X 76909677 76909681 + frameshift_variant Frame_Shift_Del DEL CTTTC CTTTC - NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 89 0 ENST00000373344.5:c.4224_4228del p.Lys1408AsnfsTer11 p.K1408Nfs*11 ENST00000373344 NM_000489.3 1408 aaGAAAGca/aaca 0 +BNIP3L UCSF GRCh37 8 26265590 26265590 + missense_variant Missense_Mutation SNP G G C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 140 39 157 0 ENST00000380629.2:c.432G>C p.Trp144Cys p.W144C ENST00000380629 NM_004331.2 144 tgG/tgC 0 +CHD4 UCSF GRCh37 12 6692539 6692539 + synonymous_variant Silent SNP T T C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 49 34 49 0 ENST00000357008.2:c.3885A>G p.Glu1295= p.E1295= ENST00000357008 NM_001273.2 1295 gaA/gaG 0 +CSNK1G1 UCSF GRCh37 15 64496629 64496639 + splice_donor_variant,intron_variant Splice_Site DEL AGGATACTTAC AGGATACTTAC GGATACTTAA NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 8 0 ENST00000303052.7:c.999+1_999+11delinsTTAAGTATCC p.X333_splice ENST00000303052 NM_022048.3 0 +EMR3 UCSF GRCh37 19 14748981 14748981 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 125 72 163 0 ENST00000253673.5:c.1420G>A p.Val474Ile p.V474I ENST00000253673 NM_032571.3 474 Gtt/Att 0 +ESX1 UCSF GRCh37 X 103495090 103495090 + missense_variant Missense_Mutation SNP G G C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 16 9 10 1 ENST00000372588.4:c.1040C>G p.Pro347Arg p.P347R ENST00000372588 NM_153448.3 347 cCt/cGt 0 +EYS UCSF GRCh37 6 66112482 66112482 + missense_variant Missense_Mutation SNP C C G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 107 85 138 0 ENST00000370616.2:c.1073G>C p.Cys358Ser p.C358S ENST00000370616 358 tGt/tCt 0 +FAM108A1 UCSF GRCh37 19 1881408 1881408 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 8 6 11 0 ENST00000292577.7:c.158T>C p.Leu53Ser p.L53S ENST00000292577 NM_001130111.1 53 tTg/tCg 0 +FGFR4 UCSF GRCh37 5 176522719 176522719 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 20 27 36 0 ENST00000292408.4:c.1816C>T p.Arg606Trp p.R606W ENST00000292408 NM_213647.1 606 Cgg/Tgg 0 +GAD1 UCSF GRCh37 2 171700560 171700565 + inframe_deletion In_Frame_Del DEL CATATG CATATG - NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 68 0 ENST00000358196.3:c.644_649del p.Thr215_Glu217delinsLys p.T215_E217delinsK ENST00000358196 NM_000817.2 215 aCATATGaa/aaa 0 +GPRC6A UCSF GRCh37 6 117114050 117114050 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.00362,snp132_rs118009892 P26_Rec1_A Untested WXS Illumina HiSeq 399 129 373 0 ENST00000310357.3:c.2036C>T p.Thr679Met p.T679M ENST00000310357 NM_148963.2 679 aCg/aTg 0 +HSPA6 UCSF GRCh37 1 161495338 161495338 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.001,1000g2011may_all_0.0102,snp132_rs41297718 P26_Rec1_A Untested WXS Illumina HiSeq 15 3 9 0 ENST00000309758.4:c.890C>A p.Thr297Lys p.T297K ENST00000309758 NM_002155.3 297 aCg/aAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 16 21 27 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGHMBP2 UCSF GRCh37 11 68707014 68707014 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 23 11 25 0 ENST00000255078.3:c.2797G>A p.Gly933Ser p.G933S ENST00000255078 NM_002180.2 933 Ggt/Agt 0 +KIF26B UCSF GRCh37 1 245848890 245848890 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 115 102 164 0 ENST00000407071.2:c.2605G>A p.Gly869Arg p.G869R ENST00000407071 NM_018012.3 869 Ggg/Agg 0 +KIR2DS4 UCSF GRCh37 19 55349113 55349113 + synonymous_variant Silent SNP G G A snp132_rs1049284 P26_Rec1_A Untested WXS Illumina HiSeq 18 4 18 1 ENST00000339924.8:c.153G>A p.Ser51= p.S51= ENST00000339924 NM_001281971.1 51 tcG/tcA 0 +KRT8 UCSF GRCh37 12 53298675 53298675 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 13 3 25 0 ENST00000293308.6:c.91T>G p.Ser31Ala p.S31A ENST00000293308 NM_002273.3 31 Tcc/Gcc 0 +MED12 UCSF GRCh37 X 70357661 70357661 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 255 131 283 0 ENST00000374080.3:c.5912A>C p.Gln1971Pro p.Q1971P ENST00000374080 1971 cAg/cCg 0 +MURC UCSF GRCh37 9 103348678 103348678 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 197 43 156 0 ENST00000307584.5:c.1040A>G p.Gln347Arg p.Q347R ENST00000307584 NM_001018116.2 347 cAg/cGg 0 +MYBPC2 UCSF GRCh37 19 50967755 50967755 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 137 36 103 0 ENST00000357701.5:c.3381C>T p.Gly1127= p.G1127= ENST00000357701 NM_004533.3 1127 ggC/ggT 0 +MYO1G UCSF GRCh37 7 45009376 45009376 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 507 60 459 0 ENST00000258787.7:c.1431C>T p.Thr477= p.T477= ENST00000258787 NM_033054.2 477 acC/acT 0 +NBPF10 UCSF GRCh37 1 145293510 145293510 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.173,snp132_rs4356110 P26_Rec1_A Untested WXS Illumina HiSeq 22 5 14 1 ENST00000342960.5:c.105C>G p.Phe35Leu p.F35L ENST00000342960 NM_001039703.5 35 ttC/ttG 0 +NBPF10 UCSF GRCh37 1 145293498 145293498 + missense_variant Missense_Mutation SNP G G C 1000g2010nov_all_0.245,1000g2011may_all_0.29821,snp132_rs4409714 P26_Rec1_A Untested WXS Illumina HiSeq 23 4 13 0 ENST00000342960.5:c.93G>C p.Lys31Asn p.K31N ENST00000342960 NM_001039703.5 31 aaG/aaC 0 +NBPF10 UCSF GRCh37 1 145293490 145293490 + missense_variant Missense_Mutation SNP G G C 1000g2010nov_all_0.242,1000g2011may_all_0.26292,snp132_rs6671335 P26_Rec1_A Untested WXS Illumina HiSeq 23 5 13 0 ENST00000342960.5:c.85G>C p.Ala29Pro p.A29P ENST00000342960 NM_001039703.5 29 Gca/Cca 0 +NCOA6 UCSF GRCh37 20 33338237 33338237 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 80 54 94 0 ENST00000359003.2:c.1761T>G p.Ile587Met p.I587M ENST00000359003 NM_014071.3 587 atT/atG 0 +PGGT1B UCSF GRCh37 5 114552629 114552629 + missense_variant Missense_Mutation SNP T T A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 22 12 25 0 ENST00000419445.1:c.885A>T p.Arg295Ser p.R295S ENST00000419445 NM_005023.3 295 agA/agT 0 +POTED UCSF GRCh37 21 14982676 14982676 + missense_variant Missense_Mutation SNP A A G snp132_rs2605913 P26_Rec1_A Untested WXS Illumina HiSeq 19 3 23 1 ENST00000299443.5:c.127A>G p.Met43Val p.M43V ENST00000299443 NM_174981.3 43 Atg/Gtg 0 +RBM45 UCSF GRCh37 2 178988920 178988920 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 7 0 ENST00000286070.5:c.1143delA p.Ala382LeufsTer7 p.A382Lfs*7 ENST00000286070 NM_152945.2 379 Aaa/aa 0 +RBMX UCSF GRCh37 X 135958696 135958696 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.08188,snp132_rs112800567 P26_Rec1_A Untested WXS Illumina HiSeq 20 6 20 1 ENST00000320676.7:c.507A>G p.Gly169= p.G169= ENST00000320676 NM_002139.3 169 ggA/ggG 0 +SCN9A UCSF GRCh37 2 167056179 167056179 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 56 42 92 0 ENST00000303354.6:c.4973T>C p.Ile1658Thr p.I1658T ENST00000303354 1658 aTc/aCc 0 +SELE UCSF GRCh37 1 169698648 169698648 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 219 49 201 0 ENST00000333360.7:c.882C>T p.Asn294= p.N294= ENST00000333360 NM_000450.2 294 aaC/aaT 0 +SFI1 UCSF GRCh37 22 32014359 32014359 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 52 57 70 0 ENST00000400288.2:c.3684C>T p.Gly1228= p.G1228= ENST00000400288 NM_001007467.2 1228 ggC/ggT 0 +SLC38A8 UCSF GRCh37 16 84050190 84050190 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 39 26 43 1 ENST00000299709.3:c.1096C>T p.Pro366Ser p.P366S ENST00000299709 NM_001080442.1 366 Cct/Tct 0 +SPP1 UCSF GRCh37 4 88903874 88903875 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 136 0 ENST00000395080.3:c.771_772del p.Ser258ArgfsTer4 p.S258Rfs*4 ENST00000395080 NM_001040058.1 257 caTTcc/cacc 0 +TBC1D5 UCSF GRCh37 3 17279718 17279718 + stop_gained Nonsense_Mutation SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 220 152 261 0 ENST00000253692.7:c.1525C>T p.Gln509Ter p.Q509* ENST00000253692 NM_014744.2 509 Caa/Taa 0 +TIAM1 UCSF GRCh37 21 32639259 32639259 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 50 45 68 0 ENST00000286827.3:c.30G>A p.Glu10= p.E10= ENST00000286827 NM_003253.2 10 gaG/gaA 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 16 76 73 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +TXLNB UCSF GRCh37 6 139563882 139563882 + synonymous_variant Silent SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 153 33 98 0 ENST00000358430.3:c.1836T>C p.Gly612= p.G612= ENST00000358430 NM_153235.3 612 ggT/ggC 0 +WNK3 UCSF GRCh37 X 54224946 54224946 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 148 42 121 0 ENST00000354646.2:c.5214C>T p.His1738= p.H1738= ENST00000354646 NM_020922.4 1738 caC/caT 0 +XPO7 UCSF GRCh37 8 21862569 21862569 + synonymous_variant Silent SNP T T C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 309 236 396 1 ENST00000252512.9:c.3234T>C p.Tyr1078= p.Y1078= ENST00000252512 NM_015024.4 1078 taT/taC 0 +ANK3 UCSF GRCh37 10 61946630 61946630 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 26 15 101 0 ENST00000280772.2:c.1928A>G p.Gln643Arg p.Q643R ENST00000280772 NM_020987.3 643 cAg/cGg 0 +ATN1 UCSF GRCh37 12 7044946 7044946 + synonymous_variant Silent SNP A A G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 268 64 581 0 ENST00000356654.4:c.516A>G p.Pro172= p.P172= ENST00000356654 NM_001007026.1 172 ccA/ccG 0 +ATRX UCSF GRCh37 X 76909677 76909681 + frameshift_variant Frame_Shift_Del DEL CTTTC CTTTC - NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 73 0 ENST00000373344.5:c.4224_4228del p.Lys1408AsnfsTer11 p.K1408Nfs*11 ENST00000373344 NM_000489.3 1408 aaGAAAGca/aaca 0 +BNIP3L UCSF GRCh37 8 26265590 26265590 + missense_variant Missense_Mutation SNP G G C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 110 24 157 0 ENST00000380629.2:c.432G>C p.Trp144Cys p.W144C ENST00000380629 NM_004331.2 144 tgG/tgC 0 +C8A UCSF GRCh37 1 57351611 57351611 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.008,1000g2011may_all_0.0213,snp132_rs77289345 P26_Rec1_B Untested WXS Illumina HiSeq 39 6 66 0 ENST00000361249.3:c.867C>T p.Phe289= p.F289= ENST00000361249 NM_000562.2 289 ttC/ttT 0 +CHD4 UCSF GRCh37 12 6692539 6692539 + synonymous_variant Silent SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 14 11 49 0 ENST00000357008.2:c.3885A>G p.Glu1295= p.E1295= ENST00000357008 NM_001273.2 1295 gaA/gaG 0 +DYNC1H1 UCSF GRCh37 14 102468978 102468978 + synonymous_variant Silent SNP T T G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 18 6 49 0 ENST00000360184.4:c.4647T>G p.Gly1549= p.G1549= ENST00000360184 NM_001376.4 1549 ggT/ggG 0 +EFS UCSF GRCh37 14 23828664 23828664 + synonymous_variant Silent SNP T T G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 26 8 72 1 ENST00000216733.3:c.1023A>C p.Pro341= p.P341= ENST00000216733 NM_005864.3 341 ccA/ccC 0 +EMR3 UCSF GRCh37 19 14748981 14748981 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 51 38 163 0 ENST00000253673.5:c.1420G>A p.Val474Ile p.V474I ENST00000253673 NM_032571.3 474 Gtt/Att 0 +EYS UCSF GRCh37 6 66112482 66112482 + missense_variant Missense_Mutation SNP C C G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 58 57 138 0 ENST00000370616.2:c.1073G>C p.Cys358Ser p.C358S ENST00000370616 358 tGt/tCt 0 +FGFR4 UCSF GRCh37 5 176522719 176522719 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 3 16 36 0 ENST00000292408.4:c.1816C>T p.Arg606Trp p.R606W ENST00000292408 NM_213647.1 606 Cgg/Tgg 0 +GAD1 UCSF GRCh37 2 171700560 171700565 + inframe_deletion In_Frame_Del DEL CATATG CATATG - NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 44 0 ENST00000358196.3:c.644_649del p.Thr215_Glu217delinsLys p.T215_E217delinsK ENST00000358196 NM_000817.2 215 aCATATGaa/aaa 0 +GPRC6A UCSF GRCh37 6 117114050 117114050 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.00362,snp132_rs118009892 P26_Rec1_B Untested WXS Illumina HiSeq 236 59 373 0 ENST00000310357.3:c.2036C>T p.Thr679Met p.T679M ENST00000310357 NM_148963.2 679 aCg/aTg 0 +HERC3 UCSF GRCh37 4 89627987 89627987 + missense_variant Missense_Mutation SNP A A T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 170 27 388 0 ENST00000264345.3:c.3029A>T p.Glu1010Val p.E1010V ENST00000264345 1010 gAg/gTg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 10 9 27 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGHMBP2 UCSF GRCh37 11 68707014 68707014 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 9 12 25 0 ENST00000255078.3:c.2797G>A p.Gly933Ser p.G933S ENST00000255078 NM_002180.2 933 Ggt/Agt 0 +IL17RA UCSF GRCh37 22 17581248 17581248 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 148 19 309 0 ENST00000319363.6:c.427C>T p.Arg143Cys p.R143C ENST00000319363 NM_014339.6 143 Cgt/Tgt 0 +KIF26B UCSF GRCh37 1 245848890 245848890 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 36 36 164 0 ENST00000407071.2:c.2605G>A p.Gly869Arg p.G869R ENST00000407071 NM_018012.3 869 Ggg/Agg 0 +MED12 UCSF GRCh37 X 70357661 70357661 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 64 43 283 0 ENST00000374080.3:c.5912A>C p.Gln1971Pro p.Q1971P ENST00000374080 1971 cAg/cCg 0 +MURC UCSF GRCh37 9 103348678 103348678 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 146 24 156 0 ENST00000307584.5:c.1040A>G p.Gln347Arg p.Q347R ENST00000307584 NM_001018116.2 347 cAg/cGg 0 +MYBPC2 UCSF GRCh37 19 50967755 50967755 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 60 12 103 0 ENST00000357701.5:c.3381C>T p.Gly1127= p.G1127= ENST00000357701 NM_004533.3 1127 ggC/ggT 0 +NCOA6 UCSF GRCh37 20 33338237 33338237 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 39 22 94 0 ENST00000359003.2:c.1761T>G p.Ile587Met p.I587M ENST00000359003 NM_014071.3 587 atT/atG 0 +PRICKLE4 UCSF GRCh37 6 41754576 41754595 + downstream_gene_variant 3'Flank INS CGCTGCTGCCGGCGGTTCCA CGCTGCTGCCGGCGGTTCCA TCTCGCTGCTGCCGGCGGTTTCC NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 6 0 ENST00000359201 0 +RBMX UCSF GRCh37 X 135958696 135958696 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.08188,snp132_rs112800567 P26_Rec1_B Untested WXS Illumina HiSeq 13 3 20 1 ENST00000320676.7:c.507A>G p.Gly169= p.G169= ENST00000320676 NM_002139.3 169 ggA/ggG 0 +SCN9A UCSF GRCh37 2 167056179 167056179 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 35 26 92 0 ENST00000303354.6:c.4973T>C p.Ile1658Thr p.I1658T ENST00000303354 1658 aTc/aCc 0 +SELE UCSF GRCh37 1 169698648 169698648 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 86 32 201 0 ENST00000333360.7:c.882C>T p.Asn294= p.N294= ENST00000333360 NM_000450.2 294 aaC/aaT 0 +SFI1 UCSF GRCh37 22 32014359 32014359 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 15 18 70 0 ENST00000400288.2:c.3684C>T p.Gly1228= p.G1228= ENST00000400288 NM_001007467.2 1228 ggC/ggT 0 +SLC38A8 UCSF GRCh37 16 84050190 84050190 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 12 12 43 1 ENST00000299709.3:c.1096C>T p.Pro366Ser p.P366S ENST00000299709 NM_001080442.1 366 Cct/Tct 0 +SPP1 UCSF GRCh37 4 88903874 88903875 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 60 0 ENST00000395080.3:c.771_772del p.Ser258ArgfsTer4 p.S258Rfs*4 ENST00000395080 NM_001040058.1 257 caTTcc/cacc 0 +TBC1D5 UCSF GRCh37 3 17279718 17279718 + stop_gained Nonsense_Mutation SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 158 127 261 0 ENST00000253692.7:c.1525C>T p.Gln509Ter p.Q509* ENST00000253692 NM_014744.2 509 Caa/Taa 0 +TIAM1 UCSF GRCh37 21 32639259 32639259 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 22 28 68 0 ENST00000286827.3:c.30G>A p.Glu10= p.E10= ENST00000286827 NM_003253.2 10 gaG/gaA 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 2 32 73 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +TRIM3 UCSF GRCh37 11 6472156 6472156 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 29 7 74 0 ENST00000345851.3:c.1836T>G p.Phe612Leu p.F612L ENST00000345851 NM_033278.3 612 ttT/ttG 0 +TXLNB UCSF GRCh37 6 139563882 139563882 + synonymous_variant Silent SNP A A G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 58 10 98 0 ENST00000358430.3:c.1836T>C p.Gly612= p.G612= ENST00000358430 NM_153235.3 612 ggT/ggC 0 +USP51 UCSF GRCh37 X 55514172 55514172 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 135 18 193 0 ENST00000500968.3:c.1201A>G p.Thr401Ala p.T401A ENST00000500968 NM_201286.3 401 Aca/Gca 0 +WNK3 UCSF GRCh37 X 54224946 54224946 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 75 14 121 0 ENST00000354646.2:c.5214C>T p.His1738= p.H1738= ENST00000354646 NM_020922.4 1738 caC/caT 0 +XPO7 UCSF GRCh37 8 21862569 21862569 + synonymous_variant Silent SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 186 184 396 1 ENST00000252512.9:c.3234T>C p.Tyr1078= p.Y1078= ENST00000252512 NM_015024.4 1078 taT/taC 0 +AKR1D1 UCSF GRCh37 7 137791441 137791441 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 182 63 221 0 ENST00000242375.3:c.667G>C p.Gly223Arg p.G223R ENST00000242375 NM_005989.3 223 Ggg/Cgg 0 +AMIGO1 UCSF GRCh37 1 110051079 110051079 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 149 67 207 0 ENST00000369862.1:c.456C>T p.Cys152= p.C152= ENST00000369862 NM_020703.2 152 tgC/tgT 0 +ATRX UCSF GRCh37 X 76938099 76938100 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P27_Pri_A Untested WXS Illumina HiSeq 121 0 ENST00000373344.5:c.2648_2649del p.Gln883ArgfsTer13 p.Q883Rfs*13 ENST00000373344 NM_000489.3 883 cAA/c 0 +BIRC6 UCSF GRCh37 2 32740799 32740823 + frameshift_variant Frame_Shift_Del DEL ATTTCATGCCATCCTAATAATCAAA ATTTCATGCCATCCTAATAATCAAA - NOVEL P27_Pri_A Untested WXS Illumina HiSeq 6 0 ENST00000421745.2:c.11312_11336del p.Ile3771SerfsTer2 p.I3771Sfs*2 ENST00000421745 NM_016252.3 3771 ATTTCATGCCATCCTAATAATCAAAag/ag 0 +CDKN2A UCSF GRCh37 9 21970993 21970993 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P27_Pri_A Untested WXS Illumina HiSeq 9 0 ENST00000304494.5:c.365del p.Gly122AlafsTer24 p.G122Afs*24 ENST00000304494 NM_000077.4 122 gGc/gc 0 +CNTNAP2 UCSF GRCh37 7 147844772 147844772 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 71 18 57 0 ENST00000361727.3:c.2744G>A p.Arg915His p.R915H ENST00000361727 NM_014141.5 915 cGc/cAc 0 +CTNND2 UCSF GRCh37 5 11364832 11364832 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 29 25 49 0 ENST00000304623.8:c.1348A>G p.Thr450Ala p.T450A ENST00000304623 NM_001332.2 450 Acc/Gcc 0 +DMWD UCSF GRCh37 19 46287928 46287928 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 68 66 142 0 ENST00000270223.6:c.1948C>T p.Pro650Ser p.P650S ENST00000270223 NM_004943.1 650 Ccc/Tcc 0 +DNAJC11 UCSF GRCh37 1 6700009 6700009 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 45 18 63 0 ENST00000377577.5:c.1206C>T p.Ala402= p.A402= ENST00000377577 NM_018198.3 402 gcC/gcT 0 +DUOXA2 UCSF GRCh37 15 45408389 45408389 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 155 113 307 0 ENST00000323030.5:c.273C>T p.Ser91= p.S91= ENST00000323030 NM_207581.3 91 agC/agT 0 +FLG UCSF GRCh37 1 152284325 152284325 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 28 18 47 0 ENST00000368799.1:c.3037T>C p.Ser1013Pro p.S1013P ENST00000368799 NM_002016.1 1013 Tcc/Ccc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 7 25 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL11 UCSF GRCh37 19 55879672 55879672 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.010,1000g2011may_all_0.0145,snp132_rs4252548 P27_Pri_A Untested WXS Illumina HiSeq 17 11 31 0 ENST00000264563.2:c.335G>A p.Arg112His p.R112H ENST00000264563 NM_000641.3 112 cGc/cAc 0 +KATNB1 UCSF GRCh37 16 57787370 57787370 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 99 49 116 0 ENST00000379661.3:c.1116C>T p.Ser372= p.S372= ENST00000379661 NM_005886.2 372 tcC/tcT 0 +KRT12 UCSF GRCh37 17 39023245 39023246 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 151 0 ENST00000251643.4:c.194dup p.Ser66Ter p.S66* ENST00000251643 NM_000223.3 65 tct/tCct 0 +KRTAP4-6 UCSF GRCh37 17 39296422 39296422 + synonymous_variant Silent SNP A A G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 24 6 19 0 ENST00000345847.4:c.318T>C p.Arg106= p.R106= ENST00000345847 NM_030976.1 106 cgT/cgC 0 +MUC6 UCSF GRCh37 11 1031684 1031684 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 106 41 158 0 ENST00000421673.2:c.406G>A p.Gly136Ser p.G136S ENST00000421673 NM_005961.2 136 Ggc/Agc 0 +MYO18B UCSF GRCh37 22 26159269 26159269 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 105 80 213 0 ENST00000536101.1:c.111C>T p.Phe37= p.F37= ENST00000536101 37 ttC/ttT 0 +NBPF1 UCSF GRCh37 1 16918473 16918473 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.016,snp132_rs60465633 P27_Pri_A somatic WXS Sanger Illumina HiSeq 19 4 23 1 ENST00000430580.2:c.44C>T p.Thr15Met p.T15M ENST00000430580 NM_017940.4 15 aCg/aTg 0 +OGFR UCSF GRCh37 20 61444845 61444845 + synonymous_variant Silent SNP G G A snp132_rs112106909 P27_Pri_A Untested WXS Illumina HiSeq 16 3 18 1 ENST00000290291.6:c.1878G>A p.Pro626= p.P626= ENST00000290291 NM_007346.2 626 ccG/ccA 0 +OR10AG1 UCSF GRCh37 11 55735772 55735772 + missense_variant Missense_Mutation SNP A A T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 109 43 166 1 ENST00000312345.2:c.168T>A p.Asn56Lys p.N56K ENST00000312345 NM_001005491.1 56 aaT/aaA 0 +POTEH UCSF GRCh37 22 16287368 16287368 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 13 5 14 0 ENST00000343518.6:c.518G>A p.Arg173His p.R173H ENST00000343518 NM_001136213.1 173 cGt/cAt 0 +PRAMEF20 UCSF GRCh37 1 13743058 13743058 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.039,1000g2011may_all_0.0457,snp132_rs77164784 P27_Pri_A Untested WXS Illumina HiSeq 14 8 17 0 ENST00000316412.5:c.247G>A p.Asp83Asn p.D83N ENST00000316412 NM_001099852.1 83 Gat/Aat 0 +PRF1 UCSF GRCh37 10 72358862 72358862 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 41 41 107 0 ENST00000373209.2:c.615C>T p.Asn205= p.N205= ENST00000373209 205 aaC/aaT 0 +PRSS50 UCSF GRCh37 3 46753929 46753929 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 32 22 43 0 ENST00000315170.7:c.965G>T p.Trp322Leu p.W322L ENST00000315170 NM_013270.4 322 tGg/tTg 0 +PSKH2 UCSF GRCh37 8 87060758 87060758 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 66 45 160 0 ENST00000276616.2:c.1091A>G p.Lys364Arg p.K364R ENST00000276616 NM_033126.1 364 aAa/aGa 0 +SCN2A UCSF GRCh37 2 166237141 166237141 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 173 26 138 0 ENST00000283256.6:c.4348T>G p.Tyr1450Asp p.Y1450D ENST00000283256 NM_021007.2 1450 Tat/Gat 0 +SEMA4D UCSF GRCh37 9 92008491 92008491 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 29 20 76 0 ENST00000356444.2:c.494C>T p.Thr165Ile p.T165I ENST00000356444 165 aCa/aTa 0 +SLCO6A1 UCSF GRCh37 5 101735273 101735273 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 61 32 63 0 ENST00000379807.3:c.1800C>T p.Val600= p.V600= ENST00000379807 NM_173488.3 600 gtC/gtT 0 +SMARCA4 UCSF GRCh37 19 11141559 11141559 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Pri_A somatic WXS Sanger Illumina HiSeq 22 4 36 0 ENST00000344626.4:c.3536A>G p.Asn1179Ser p.N1179S ENST00000344626 NM_003072.3 1179 aAt/aGt 0 +SPHKAP UCSF GRCh37 2 228883637 228883637 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 114 104 199 0 ENST00000392056.3:c.1933A>G p.Arg645Gly p.R645G ENST00000392056 NM_001142644.1 645 Agg/Ggg 0 +TMEM95 UCSF GRCh37 17 7258580 7258580 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 69 42 118 0 ENST00000576060.1:c.57C>T p.Phe19= p.F19= ENST00000576060 19 ttC/ttT 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 14 71 71 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +WDR62 UCSF GRCh37 19 36585008 36585008 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 114 45 166 0 ENST00000270301.7:c.2409G>A p.Glu803= p.E803= ENST00000270301 803 gaG/gaA 0 +ZKSCAN4 UCSF GRCh37 6 28213206 28213206 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 280 197 579 0 ENST00000377294.2:c.1326G>C p.Arg442Ser p.R442S ENST00000377294 NM_019110.3 442 agG/agC 0 +ZSWIM5 UCSF GRCh37 1 45516885 45516885 + synonymous_variant Silent SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 59 66 186 0 ENST00000359600.5:c.1293A>G p.Lys431= p.K431= ENST00000359600 NM_020883.1 431 aaA/aaG 0 +ABI3BP UCSF GRCh37 3 100712213 100712213 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 44 5 75 0 ENST00000284322.5:c.37G>T p.Gly13Trp p.G13W ENST00000284322 NM_015429.3 13 Ggg/Tgg 0 +AKR1D1 UCSF GRCh37 7 137791441 137791441 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 137 63 221 0 ENST00000242375.3:c.667G>C p.Gly223Arg p.G223R ENST00000242375 NM_005989.3 223 Ggg/Cgg 0 +AMIGO1 UCSF GRCh37 1 110051079 110051079 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 76 38 207 0 ENST00000369862.1:c.456C>T p.Cys152= p.C152= ENST00000369862 NM_020703.2 152 tgC/tgT 0 +ANKRD22 UCSF GRCh37 10 90591731 90591731 + missense_variant Missense_Mutation SNP A A C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 36 14 130 0 ENST00000371930.4:c.74T>G p.Val25Gly p.V25G ENST00000371930 NM_144590.2 25 gTg/gGg 0 +ATP7B UCSF GRCh37 13 52524503 52524503 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 36 4 121 0 ENST00000242839.4:c.2480G>T p.Arg827Leu p.R827L ENST00000242839 NM_000053.3 827 cGg/cTg 0 +ATRX UCSF GRCh37 X 76938099 76938100 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P27_Pri_B Untested WXS Illumina HiSeq 96 0 ENST00000373344.5:c.2648_2649del p.Gln883ArgfsTer13 p.Q883Rfs*13 ENST00000373344 NM_000489.3 883 cAA/c 0 +B3GNT3 UCSF GRCh37 19 17918779 17918779 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 24 4 69 0 ENST00000318683.6:c.163C>A p.Arg55Ser p.R55S ENST00000318683 NM_014256.3 55 Cgc/Agc 0 +CBX4 UCSF GRCh37 17 77808322 77808322 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 24 3 58 0 ENST00000269397.4:c.1119G>T p.Pro373= p.P373= ENST00000269397 NM_003655.2 373 ccG/ccT 0 +CCDC60 UCSF GRCh37 12 119773023 119773023 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 34 4 105 0 ENST00000327554.2:c.42C>A p.Pro14= p.P14= ENST00000327554 NM_178499.3 14 ccC/ccA 0 +CNTNAP2 UCSF GRCh37 7 147844772 147844772 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 34 16 57 0 ENST00000361727.3:c.2744G>A p.Arg915His p.R915H ENST00000361727 NM_014141.5 915 cGc/cAc 0 +CTNND2 UCSF GRCh37 5 11364832 11364832 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 16 10 49 0 ENST00000304623.8:c.1348A>G p.Thr450Ala p.T450A ENST00000304623 NM_001332.2 450 Acc/Gcc 0 +DMWD UCSF GRCh37 19 46287928 46287928 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 37 42 142 0 ENST00000270223.6:c.1948C>T p.Pro650Ser p.P650S ENST00000270223 NM_004943.1 650 Ccc/Tcc 0 +DNAJC11 UCSF GRCh37 1 6700009 6700009 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 20 13 63 0 ENST00000377577.5:c.1206C>T p.Ala402= p.A402= ENST00000377577 NM_018198.3 402 gcC/gcT 0 +DUOXA2 UCSF GRCh37 15 45408389 45408389 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 67 42 307 0 ENST00000323030.5:c.273C>T p.Ser91= p.S91= ENST00000323030 NM_207581.3 91 agC/agT 0 +FLG UCSF GRCh37 1 152284325 152284325 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 15 10 47 0 ENST00000368799.1:c.3037T>C p.Ser1013Pro p.S1013P ENST00000368799 NM_002016.1 1013 Tcc/Ccc 0 +FMN2 UCSF GRCh37 1 240255560 240255560 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 35 19 85 0 ENST00000319653.9:c.151G>A p.Gly51Arg p.G51R ENST00000319653 NM_020066.4 51 Ggg/Agg 0 +FUCA1 UCSF GRCh37 1 24181025 24181025 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 36 4 51 0 ENST00000374479.3:c.794G>T p.Trp265Leu p.W265L ENST00000374479 NM_000147.4 265 tGg/tTg 0 +GGA2 UCSF GRCh37 16 23481419 23481419 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 27 3 57 0 ENST00000309859.4:c.1518G>T p.Thr506= p.T506= ENST00000309859 NM_015044.4 506 acG/acT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 10 16 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +INPP5F UCSF GRCh37 10 121556378 121556378 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 13 3 37 0 ENST00000361976.2:c.821C>A p.Pro274Gln p.P274Q ENST00000361976 NM_014937.3 274 cCa/cAa 0 +KATNB1 UCSF GRCh37 16 57787370 57787370 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 24 27 116 0 ENST00000379661.3:c.1116C>T p.Ser372= p.S372= ENST00000379661 NM_005886.2 372 tcC/tcT 0 +KRT12 UCSF GRCh37 17 39023245 39023246 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 63 0 ENST00000251643.4:c.194dup p.Ser66Ter p.S66* ENST00000251643 NM_000223.3 65 tct/tCct 0 +MATK UCSF GRCh37 19 3784435 3784435 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 19 3 28 0 ENST00000310132.6:c.147G>T p.Pro49= p.P49= ENST00000310132 NM_139355.2 49 ccG/ccT 0 +MUC6 UCSF GRCh37 11 1031684 1031684 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 46 18 158 0 ENST00000421673.2:c.406G>A p.Gly136Ser p.G136S ENST00000421673 NM_005961.2 136 Ggc/Agc 0 +MYO18B UCSF GRCh37 22 26159269 26159269 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 36 24 213 0 ENST00000536101.1:c.111C>T p.Phe37= p.F37= ENST00000536101 37 ttC/ttT 0 +NBPF1 UCSF GRCh37 1 16893813 16893813 + synonymous_variant Silent SNP A A G snp132_rs58611269 P27_Pri_B Untested WXS Illumina HiSeq 11 4 19 0 ENST00000430580.2:c.2700T>C p.Pro900= p.P900= ENST00000430580 NM_017940.4 900 ccT/ccC 0 +OPN4 UCSF GRCh37 10 88418431 88418431 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 18 3 31 0 ENST00000241891.5:c.615C>A p.Pro205= p.P205= ENST00000241891 NM_033282.3 205 ccC/ccA 0 +OR10AG1 UCSF GRCh37 11 55735772 55735772 + missense_variant Missense_Mutation SNP A A T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 55 23 166 1 ENST00000312345.2:c.168T>A p.Asn56Lys p.N56K ENST00000312345 NM_001005491.1 56 aaT/aaA 0 +PRF1 UCSF GRCh37 10 72358862 72358862 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 18 15 107 0 ENST00000373209.2:c.615C>T p.Asn205= p.N205= ENST00000373209 205 aaC/aaT 0 +PRSS50 UCSF GRCh37 3 46753929 46753929 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 19 11 43 0 ENST00000315170.7:c.965G>T p.Trp322Leu p.W322L ENST00000315170 NM_013270.4 322 tGg/tTg 0 +PSKH2 UCSF GRCh37 8 87060758 87060758 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 38 28 160 0 ENST00000276616.2:c.1091A>G p.Lys364Arg p.K364R ENST00000276616 NM_033126.1 364 aAa/aGa 0 +RASGRP2 UCSF GRCh37 11 64509576 64509576 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 24 3 73 0 ENST00000354024.3:c.82G>T p.Gly28Trp p.G28W ENST00000354024 NM_153819.1 28 Ggg/Tgg 0 +SCN2A UCSF GRCh37 2 166237141 166237141 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 106 13 138 0 ENST00000283256.6:c.4348T>G p.Tyr1450Asp p.Y1450D ENST00000283256 NM_021007.2 1450 Tat/Gat 0 +SEMA4D UCSF GRCh37 9 92008491 92008491 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 28 17 76 0 ENST00000356444.2:c.494C>T p.Thr165Ile p.T165I ENST00000356444 165 aCa/aTa 0 +SH3BGRL2 UCSF GRCh37 6 80383448 80383448 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 29 4 54 0 ENST00000369838.4:c.163C>A p.Pro55Thr p.P55T ENST00000369838 NM_031469.2 55 Ccg/Acg 0 +SLCO6A1 UCSF GRCh37 5 101735273 101735273 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 37 16 63 0 ENST00000379807.3:c.1800C>T p.Val600= p.V600= ENST00000379807 NM_173488.3 600 gtC/gtT 0 +SMARCA4 UCSF GRCh37 19 11141559 11141559 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 13 5 36 0 ENST00000344626.4:c.3536A>G p.Asn1179Ser p.N1179S ENST00000344626 NM_003072.3 1179 aAt/aGt 0 +SPHKAP UCSF GRCh37 2 228883637 228883637 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 82 51 199 0 ENST00000392056.3:c.1933A>G p.Arg645Gly p.R645G ENST00000392056 NM_001142644.1 645 Agg/Ggg 0 +TMEM95 UCSF GRCh37 17 7258580 7258580 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 26 17 118 0 ENST00000576060.1:c.57C>T p.Phe19= p.F19= ENST00000576060 19 ttC/ttT 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 7 25 71 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +WDR62 UCSF GRCh37 19 36585008 36585008 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 90 40 166 0 ENST00000270301.7:c.2409G>A p.Glu803= p.E803= ENST00000270301 803 gaG/gaA 0 +ZAK UCSF GRCh37 2 174081976 174081976 + missense_variant,splice_region_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 14 3 29 0 ENST00000375213.3:c.985C>A p.Pro329Thr p.P329T ENST00000375213 NM_016653.2 329 Ccg/Acg 0 +ZKSCAN4 UCSF GRCh37 6 28213206 28213206 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 146 103 579 0 ENST00000377294.2:c.1326G>C p.Arg442Ser p.R442S ENST00000377294 NM_019110.3 442 agG/agC 0 +ZNF365 UCSF GRCh37 10 64416220 64416220 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.011,1000g2011may_all_0.0406,snp132_rs76895268 P27_Pri_B Untested WXS Illumina HiSeq 49 6 71 0 ENST00000410046.3:c.1194C>T p.Asp398= p.D398= ENST00000410046 NM_199451.2 398 gaC/gaT 0 +ZNF674 UCSF GRCh37 X 46360197 46360197 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 28 4 47 0 ENST00000523374.1:c.827G>T p.Gly276Val p.G276V ENST00000523374 NM_001039891.2 276 gGg/gTg 0 +ZSWIM5 UCSF GRCh37 1 45516885 45516885 + synonymous_variant Silent SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 35 33 186 0 ENST00000359600.5:c.1293A>G p.Lys431= p.K431= ENST00000359600 NM_020883.1 431 aaA/aaG 0 +ZYX UCSF GRCh37 7 143079428 143079428 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 34 4 89 0 ENST00000322764.5:c.296C>A p.Pro99Gln p.P99Q ENST00000322764 NM_003461.4 99 cCg/cAg 0 +AKR1D1 UCSF GRCh37 7 137791441 137791441 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 166 85 221 0 ENST00000242375.3:c.667G>C p.Gly223Arg p.G223R ENST00000242375 NM_005989.3 223 Ggg/Cgg 0 +AMIGO1 UCSF GRCh37 1 110051079 110051079 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 105 86 207 0 ENST00000369862.1:c.456C>T p.Cys152= p.C152= ENST00000369862 NM_020703.2 152 tgC/tgT 0 +ATP13A2 UCSF GRCh37 1 17316753 17316753 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 58 9 77 0 ENST00000326735.8:c.2281G>T p.Ala761Ser p.A761S ENST00000326735 761 Gcc/Tcc 0 +ATRX UCSF GRCh37 X 76938099 76938100 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 120 0 ENST00000373344.5:c.2648_2649del p.Gln883ArgfsTer13 p.Q883Rfs*13 ENST00000373344 NM_000489.3 883 cAA/c 0 +CDH2 UCSF GRCh37 18 25727679 25727679 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 54 28 81 0 ENST00000269141.3:c.130G>C p.Val44Leu p.V44L ENST00000269141 NM_001792.3 44 Gtc/Ctc 0 +CDKN2A UCSF GRCh37 9 21970993 21970993 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 8 0 ENST00000304494.5:c.365del p.Gly122AlafsTer24 p.G122Afs*24 ENST00000304494 NM_000077.4 122 gGc/gc 0 +CNTNAP2 UCSF GRCh37 7 147844772 147844772 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 52 24 57 0 ENST00000361727.3:c.2744G>A p.Arg915His p.R915H ENST00000361727 NM_014141.5 915 cGc/cAc 0 +CTNND2 UCSF GRCh37 5 11364832 11364832 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 29 20 49 0 ENST00000304623.8:c.1348A>G p.Thr450Ala p.T450A ENST00000304623 NM_001332.2 450 Acc/Gcc 0 +DHX34 UCSF GRCh37 19 47876868 47876868 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 30 16 43 0 ENST00000328771.4:c.1975C>T p.Arg659Trp p.R659W ENST00000328771 NM_014681.5 659 Cgg/Tgg 0 +DMWD UCSF GRCh37 19 46287928 46287928 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 74 46 142 0 ENST00000270223.6:c.1948C>T p.Pro650Ser p.P650S ENST00000270223 NM_004943.1 650 Ccc/Tcc 0 +DNAJC11 UCSF GRCh37 1 6700009 6700009 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 23 17 63 0 ENST00000377577.5:c.1206C>T p.Ala402= p.A402= ENST00000377577 NM_018198.3 402 gcC/gcT 0 +DUOXA2 UCSF GRCh37 15 45408389 45408389 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 168 101 307 0 ENST00000323030.5:c.273C>T p.Ser91= p.S91= ENST00000323030 NM_207581.3 91 agC/agT 0 +EYA2 UCSF GRCh37 20 45771717 45771717 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 104 78 170 0 ENST00000327619.5:c.908G>A p.Arg303His p.R303H ENST00000327619 NM_005244.4 303 cGc/cAc 0 +FLG UCSF GRCh37 1 152284325 152284325 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 24 16 47 0 ENST00000368799.1:c.3037T>C p.Ser1013Pro p.S1013P ENST00000368799 NM_002016.1 1013 Tcc/Ccc 0 +FMN2 UCSF GRCh37 1 240255560 240255560 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 60 48 85 0 ENST00000319653.9:c.151G>A p.Gly51Arg p.G51R ENST00000319653 NM_020066.4 51 Ggg/Agg 0 +GNE UCSF GRCh37 9 36217503 36217503 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 172 69 188 0 ENST00000377902.5:c.2028C>G p.Ile676Met p.I676M ENST00000377902 NM_001190383.1 676 atC/atG 0 +GNE UCSF GRCh37 9 36217533 36217533 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 166 61 171 0 ENST00000377902.5:c.1998C>G p.Ile666Met p.I666M ENST00000377902 NM_001190383.1 666 atC/atG 0 +GPR44 UCSF GRCh37 11 60620792 60620792 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 38 22 77 0 ENST00000332539.4:c.404G>A p.Arg135Gln p.R135Q ENST00000332539 NM_004778.2 135 cGg/cAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 12 11 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL11 UCSF GRCh37 19 55879672 55879672 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.010,1000g2011may_all_0.0145,snp132_rs4252548 P27_Rec1_A Untested WXS Illumina HiSeq 15 12 31 0 ENST00000264563.2:c.335G>A p.Arg112His p.R112H ENST00000264563 NM_000641.3 112 cGc/cAc 0 +KATNB1 UCSF GRCh37 16 57787370 57787370 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 54 45 116 0 ENST00000379661.3:c.1116C>T p.Ser372= p.S372= ENST00000379661 NM_005886.2 372 tcC/tcT 0 +KRT12 UCSF GRCh37 17 39023245 39023246 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 129 0 ENST00000251643.4:c.194dup p.Ser66Ter p.S66* ENST00000251643 NM_000223.3 65 tct/tCct 0 +MUC6 UCSF GRCh37 11 1031684 1031684 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 83 48 158 0 ENST00000421673.2:c.406G>A p.Gly136Ser p.G136S ENST00000421673 NM_005961.2 136 Ggc/Agc 0 +MYO18A UCSF GRCh37 17 27437604 27437604 + synonymous_variant Silent SNP G G T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 57 8 53 0 ENST00000527372.1:c.2937C>A p.Gly979= p.G979= ENST00000527372 NM_078471.3 979 ggC/ggA 0 +MYO18B UCSF GRCh37 22 26159269 26159269 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 108 72 213 0 ENST00000536101.1:c.111C>T p.Phe37= p.F37= ENST00000536101 37 ttC/ttT 0 +NBPF1 UCSF GRCh37 1 16893813 16893813 + synonymous_variant Silent SNP A A G snp132_rs58611269 P27_Rec1_A Untested WXS Illumina HiSeq 15 3 19 0 ENST00000430580.2:c.2700T>C p.Pro900= p.P900= ENST00000430580 NM_017940.4 900 ccT/ccC 0 +OR10AG1 UCSF GRCh37 11 55735772 55735772 + missense_variant Missense_Mutation SNP A A T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 86 60 166 1 ENST00000312345.2:c.168T>A p.Asn56Lys p.N56K ENST00000312345 NM_001005491.1 56 aaT/aaA 0 +PRAMEF20 UCSF GRCh37 1 13743058 13743058 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.039,1000g2011may_all_0.0457,snp132_rs77164784 P27_Rec1_A Untested WXS Illumina HiSeq 15 3 17 0 ENST00000316412.5:c.247G>A p.Asp83Asn p.D83N ENST00000316412 NM_001099852.1 83 Gat/Aat 0 +PRB1 UCSF GRCh37 12 11506350 11506350 + intron_variant Intron SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 11 3 14 0 ENST00000500254.2:c.314-26G>A *105* ENST00000500254 NM_199353.2 0 +PRF1 UCSF GRCh37 10 72358862 72358862 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 48 39 107 0 ENST00000373209.2:c.615C>T p.Asn205= p.N205= ENST00000373209 205 aaC/aaT 0 +PRSS50 UCSF GRCh37 3 46753929 46753929 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 22 17 43 0 ENST00000315170.7:c.965G>T p.Trp322Leu p.W322L ENST00000315170 NM_013270.4 322 tGg/tTg 0 +PSKH2 UCSF GRCh37 8 87060758 87060758 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 80 51 160 0 ENST00000276616.2:c.1091A>G p.Lys364Arg p.K364R ENST00000276616 NM_033126.1 364 aAa/aGa 0 +SCN2A UCSF GRCh37 2 166237141 166237141 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 105 40 138 0 ENST00000283256.6:c.4348T>G p.Tyr1450Asp p.Y1450D ENST00000283256 NM_021007.2 1450 Tat/Gat 0 +SEMA4D UCSF GRCh37 9 92008491 92008491 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 28 32 76 0 ENST00000356444.2:c.494C>T p.Thr165Ile p.T165I ENST00000356444 165 aCa/aTa 0 +SLCO6A1 UCSF GRCh37 5 101735273 101735273 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 40 27 63 0 ENST00000379807.3:c.1800C>T p.Val600= p.V600= ENST00000379807 NM_173488.3 600 gtC/gtT 0 +SMARCA4 UCSF GRCh37 19 11141559 11141559 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Rec1_A somatic WXS Sanger Illumina HiSeq 17 5 36 0 ENST00000344626.4:c.3536A>G p.Asn1179Ser p.N1179S ENST00000344626 NM_003072.3 1179 aAt/aGt 0 +SPHKAP UCSF GRCh37 2 228883637 228883637 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 105 89 199 0 ENST00000392056.3:c.1933A>G p.Arg645Gly p.R645G ENST00000392056 NM_001142644.1 645 Agg/Ggg 0 +ST18 UCSF GRCh37 8 53084929 53084929 + synonymous_variant Silent SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 140 72 230 1 ENST00000276480.7:c.492A>G p.Ala164= p.A164= ENST00000276480 NM_014682.2 164 gcA/gcG 0 +STAT4 UCSF GRCh37 2 191937835 191937835 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 203 139 466 0 ENST00000358470.4:c.454A>G p.Asn152Asp p.N152D ENST00000358470 NM_001243835.1 152 Aac/Gac 0 +STYK1 UCSF GRCh37 12 10780287 10780287 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 184 112 300 0 ENST00000075503.3:c.670A>G p.Thr224Ala p.T224A ENST00000075503 NM_018423.2 224 Aca/Gca 0 +TH1L UCSF GRCh37 20 57569284 57569284 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 96 54 169 0 ENST00000602795.1:c.1755G>A p.Thr585= p.T585= ENST00000602795 NM_198976.2 585 acG/acA 0 +TMEM95 UCSF GRCh37 17 7258580 7258580 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 56 41 118 0 ENST00000576060.1:c.57C>T p.Phe19= p.F19= ENST00000576060 19 ttC/ttT 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 12 56 71 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +WDR62 UCSF GRCh37 19 36585008 36585008 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 73 58 166 0 ENST00000270301.7:c.2409G>A p.Glu803= p.E803= ENST00000270301 803 gaG/gaA 0 +XKRX UCSF GRCh37 X 100169574 100169574 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 70 186 249 0 ENST00000372956.2:c.1103A>C p.Lys368Thr p.K368T ENST00000372956 368 aAg/aCg 0 +ZKSCAN4 UCSF GRCh37 6 28213206 28213206 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 316 209 579 0 ENST00000377294.2:c.1326G>C p.Arg442Ser p.R442S ENST00000377294 NM_019110.3 442 agG/agC 0 +ZSWIM5 UCSF GRCh37 1 45516885 45516885 + synonymous_variant Silent SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 74 41 186 0 ENST00000359600.5:c.1293A>G p.Lys431= p.K431= ENST00000359600 NM_020883.1 431 aaA/aaG 0 +AKR1D1 UCSF GRCh37 7 137791441 137791441 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 168 58 221 0 ENST00000242375.3:c.667G>C p.Gly223Arg p.G223R ENST00000242375 NM_005989.3 223 Ggg/Cgg 0 +AMIGO1 UCSF GRCh37 1 110051079 110051079 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 86 41 207 0 ENST00000369862.1:c.456C>T p.Cys152= p.C152= ENST00000369862 NM_020703.2 152 tgC/tgT 0 +ATRX UCSF GRCh37 X 76938099 76938100 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 87 0 ENST00000373344.5:c.2648_2649del p.Gln883ArgfsTer13 p.Q883Rfs*13 ENST00000373344 NM_000489.3 883 cAA/c 0 +CDH2 UCSF GRCh37 18 25727679 25727679 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 57 16 81 0 ENST00000269141.3:c.130G>C p.Val44Leu p.V44L ENST00000269141 NM_001792.3 44 Gtc/Ctc 0 +CDKN2A UCSF GRCh37 9 21970993 21970993 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 23 0 ENST00000304494.5:c.365del p.Gly122AlafsTer24 p.G122Afs*24 ENST00000304494 NM_000077.4 122 gGc/gc 0 +CNTNAP2 UCSF GRCh37 7 147844772 147844772 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 36 20 57 0 ENST00000361727.3:c.2744G>A p.Arg915His p.R915H ENST00000361727 NM_014141.5 915 cGc/cAc 0 +CTNND2 UCSF GRCh37 5 11364832 11364832 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 14 15 49 0 ENST00000304623.8:c.1348A>G p.Thr450Ala p.T450A ENST00000304623 NM_001332.2 450 Acc/Gcc 0 +DHX34 UCSF GRCh37 19 47876868 47876868 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 24 13 43 0 ENST00000328771.4:c.1975C>T p.Arg659Trp p.R659W ENST00000328771 NM_014681.5 659 Cgg/Tgg 0 +DMWD UCSF GRCh37 19 46287928 46287928 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 58 40 142 0 ENST00000270223.6:c.1948C>T p.Pro650Ser p.P650S ENST00000270223 NM_004943.1 650 Ccc/Tcc 0 +DNAJC11 UCSF GRCh37 1 6700009 6700009 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 29 21 63 0 ENST00000377577.5:c.1206C>T p.Ala402= p.A402= ENST00000377577 NM_018198.3 402 gcC/gcT 0 +DUOXA2 UCSF GRCh37 15 45408389 45408389 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 101 49 307 0 ENST00000323030.5:c.273C>T p.Ser91= p.S91= ENST00000323030 NM_207581.3 91 agC/agT 0 +EYA2 UCSF GRCh37 20 45771717 45771717 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 121 37 170 0 ENST00000327619.5:c.908G>A p.Arg303His p.R303H ENST00000327619 NM_005244.4 303 cGc/cAc 0 +FLG UCSF GRCh37 1 152284325 152284325 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 19 15 47 0 ENST00000368799.1:c.3037T>C p.Ser1013Pro p.S1013P ENST00000368799 NM_002016.1 1013 Tcc/Ccc 0 +FMN2 UCSF GRCh37 1 240255560 240255560 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 34 24 85 0 ENST00000319653.9:c.151G>A p.Gly51Arg p.G51R ENST00000319653 NM_020066.4 51 Ggg/Agg 0 +GNE UCSF GRCh37 9 36217503 36217503 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 158 38 188 0 ENST00000377902.5:c.2028C>G p.Ile676Met p.I676M ENST00000377902 NM_001190383.1 676 atC/atG 0 +GNE UCSF GRCh37 9 36217533 36217533 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 154 35 171 0 ENST00000377902.5:c.1998C>G p.Ile666Met p.I666M ENST00000377902 NM_001190383.1 666 atC/atG 0 +GPR44 UCSF GRCh37 11 60620792 60620792 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 31 11 77 0 ENST00000332539.4:c.404G>A p.Arg135Gln p.R135Q ENST00000332539 NM_004778.2 135 cGg/cAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 9 20 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KATNB1 UCSF GRCh37 16 57787370 57787370 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 42 20 116 0 ENST00000379661.3:c.1116C>T p.Ser372= p.S372= ENST00000379661 NM_005886.2 372 tcC/tcT 0 +KRT12 UCSF GRCh37 17 39023245 39023246 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 70 0 ENST00000251643.4:c.194dup p.Ser66Ter p.S66* ENST00000251643 NM_000223.3 65 tct/tCct 0 +MUC6 UCSF GRCh37 11 1031684 1031684 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 60 24 158 0 ENST00000421673.2:c.406G>A p.Gly136Ser p.G136S ENST00000421673 NM_005961.2 136 Ggc/Agc 0 +MYO18B UCSF GRCh37 22 26159269 26159269 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 67 46 213 0 ENST00000536101.1:c.111C>T p.Phe37= p.F37= ENST00000536101 37 ttC/ttT 0 +OR10AG1 UCSF GRCh37 11 55735772 55735772 + missense_variant Missense_Mutation SNP A A T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 78 65 166 1 ENST00000312345.2:c.168T>A p.Asn56Lys p.N56K ENST00000312345 NM_001005491.1 56 aaT/aaA 0 +PRF1 UCSF GRCh37 10 72358862 72358862 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 35 20 107 0 ENST00000373209.2:c.615C>T p.Asn205= p.N205= ENST00000373209 205 aaC/aaT 0 +PRSS50 UCSF GRCh37 3 46753929 46753929 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 12 14 43 0 ENST00000315170.7:c.965G>T p.Trp322Leu p.W322L ENST00000315170 NM_013270.4 322 tGg/tTg 0 +PSKH2 UCSF GRCh37 8 87060758 87060758 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 62 35 160 0 ENST00000276616.2:c.1091A>G p.Lys364Arg p.K364R ENST00000276616 NM_033126.1 364 aAa/aGa 0 +SCN2A UCSF GRCh37 2 166237141 166237141 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 95 34 138 0 ENST00000283256.6:c.4348T>G p.Tyr1450Asp p.Y1450D ENST00000283256 NM_021007.2 1450 Tat/Gat 0 +SEMA4D UCSF GRCh37 9 92008491 92008491 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 31 28 76 0 ENST00000356444.2:c.494C>T p.Thr165Ile p.T165I ENST00000356444 165 aCa/aTa 0 +SLCO6A1 UCSF GRCh37 5 101735273 101735273 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 45 26 63 0 ENST00000379807.3:c.1800C>T p.Val600= p.V600= ENST00000379807 NM_173488.3 600 gtC/gtT 0 +SMARCA4 UCSF GRCh37 19 11141559 11141559 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 13 9 36 0 ENST00000344626.4:c.3536A>G p.Asn1179Ser p.N1179S ENST00000344626 NM_003072.3 1179 aAt/aGt 0 +SPHKAP UCSF GRCh37 2 228883637 228883637 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 122 66 199 0 ENST00000392056.3:c.1933A>G p.Arg645Gly p.R645G ENST00000392056 NM_001142644.1 645 Agg/Ggg 0 +ST18 UCSF GRCh37 8 53084929 53084929 + synonymous_variant Silent SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 131 48 230 1 ENST00000276480.7:c.492A>G p.Ala164= p.A164= ENST00000276480 NM_014682.2 164 gcA/gcG 0 +STAT4 UCSF GRCh37 2 191937835 191937835 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 212 86 466 0 ENST00000358470.4:c.454A>G p.Asn152Asp p.N152D ENST00000358470 NM_001243835.1 152 Aac/Gac 0 +STYK1 UCSF GRCh37 12 10780287 10780287 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 165 68 300 0 ENST00000075503.3:c.670A>G p.Thr224Ala p.T224A ENST00000075503 NM_018423.2 224 Aca/Gca 0 +TH1L UCSF GRCh37 20 57569284 57569284 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 62 20 169 0 ENST00000602795.1:c.1755G>A p.Thr585= p.T585= ENST00000602795 NM_198976.2 585 acG/acA 0 +TMEM95 UCSF GRCh37 17 7258580 7258580 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 44 29 118 0 ENST00000576060.1:c.57C>T p.Phe19= p.F19= ENST00000576060 19 ttC/ttT 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 5 29 71 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +WDR62 UCSF GRCh37 19 36585008 36585008 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 83 57 166 0 ENST00000270301.7:c.2409G>A p.Glu803= p.E803= ENST00000270301 803 gaG/gaA 0 +XKRX UCSF GRCh37 X 100169574 100169574 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 68 136 249 0 ENST00000372956.2:c.1103A>C p.Lys368Thr p.K368T ENST00000372956 368 aAg/aCg 0 +ZKSCAN4 UCSF GRCh37 6 28213206 28213206 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 218 149 579 0 ENST00000377294.2:c.1326G>C p.Arg442Ser p.R442S ENST00000377294 NM_019110.3 442 agG/agC 0 +ZSWIM5 UCSF GRCh37 1 45516885 45516885 + synonymous_variant Silent SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 42 48 186 0 ENST00000359600.5:c.1293A>G p.Lys431= p.K431= ENST00000359600 NM_020883.1 431 aaA/aaG 0 +AMPD1 UCSF GRCh37 1 115222309 115222309 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Pri Untested WXS Illumina HiSeq 53 37 81 0 ENST00000520113.2:c.887G>A p.Arg296His p.R296H ENST00000520113 296 cGc/cAc 0 +AMZ2 UCSF GRCh37 17 66250631 66250631 + missense_variant Missense_Mutation SNP T T C NOVEL P28_Pri Untested WXS Illumina HiSeq 114 47 171 0 ENST00000359904.3:c.673T>C p.Ser225Pro p.S225P ENST00000359904 NM_016627.4 225 Tct/Cct 0 +ARSI UCSF GRCh37 5 149677736 149677736 + missense_variant Missense_Mutation SNP G G A NOVEL P28_Pri Untested WXS Illumina HiSeq 97 60 145 0 ENST00000328668.7:c.751C>T p.Arg251Cys p.R251C ENST00000328668 NM_001012301.2 251 Cgc/Tgc 0 +ATRX UCSF GRCh37 X 76937611 76937615 + frameshift_variant Frame_Shift_Del DEL CTTTT CTTTT - NOVEL P28_Pri Untested WXS Illumina HiSeq 180 0 ENST00000373344.5:c.3133_3137delAAAAG p.Lys1045Ter p.K1045* ENST00000373344 NM_000489.3 1045 AAAAGt/t 0 +C20orf96(NM_080571:exon2:c.17+2->TA) UCSF GRCh37 20 271226 271227 + splice_region_variant,intron_variant Splice_Region INS - - TA NOVEL P28_Pri Untested WXS Illumina HiSeq 7 0 ENST00000360321.2:c.20+6_20+7dup p.X7_splice ENST00000360321 NM_153269.2 0 +CYB5D2 UCSF GRCh37 17 4053185 4053185 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P28_Pri Untested WXS Illumina HiSeq 30 10 50 0 ENST00000301391.3:c.251G>A p.Gly84Asp p.G84D ENST00000301391 NM_144611.3 84 gGc/gAc 0 +FLG UCSF GRCh37 1 152284806 152284806 + synonymous_variant Silent SNP C C T snp132_rs71625190 P28_Pri Untested WXS Illumina HiSeq 16 7 15 1 ENST00000368799.1:c.2556G>A p.Arg852= p.R852= ENST00000368799 NM_002016.1 852 agG/agA 0 +FZR1 UCSF GRCh37 19 3533340 3533340 + missense_variant Missense_Mutation SNP C C G NOVEL P28_Pri Untested WXS Illumina HiSeq 83 12 72 0 ENST00000395095.3:c.1291C>G p.Pro431Ala p.P431A ENST00000395095 NM_001136198.1 431 Ccc/Gcc 0 +GPR98 UCSF GRCh37 5 90085648 90085648 + missense_variant Missense_Mutation SNP G G A NOVEL P28_Pri Untested WXS Illumina HiSeq 29 18 41 0 ENST00000405460.2:c.14023G>A p.Gly4675Ser p.G4675S ENST00000405460 NM_032119.3 4675 Ggc/Agc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Pri Untested WXS Illumina HiSeq 13 13 24 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KRTAP4-9 UCSF GRCh37 17 39261693 39261693 + missense_variant Missense_Mutation SNP A A T 1000g2010nov_all_0.281,snp132_rs113059833 P28_Pri Untested WXS Illumina HiSeq 32 5 41 0 ENST00000391415.1:c.53A>T p.Asp18Val p.D18V ENST00000391415 NM_001146041.1 18 gAc/gTc 0 +LOXHD1 UCSF GRCh37 18 44152078 44152078 + missense_variant Missense_Mutation SNP A A G NOVEL P28_Pri Untested WXS Illumina HiSeq 107 64 165 0 ENST00000398722.4:c.1184T>C p.Leu395Pro p.L395P ENST00000398722 395 cTa/cCa 0 +MICAL2 UCSF GRCh37 11 12263921 12263921 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Pri Untested WXS Illumina HiSeq 99 56 138 0 ENST00000256194.4:c.2498C>T p.Ala833Val p.A833V ENST00000256194 NM_014632.2 833 gCg/gTg 0 +MLL3 UCSF GRCh37 7 151945313 151945313 + synonymous_variant Silent SNP A A G NOVEL P28_Pri Untested WXS Illumina HiSeq 22 3 22 1 ENST00000262189.6:c.2206T>C p.Leu736= p.L736= ENST00000262189 NM_170606.2 736 Ttg/Ctg 0 +PKP2 UCSF GRCh37 12 33031211 33031211 + synonymous_variant Silent SNP C C T NOVEL P28_Pri Untested WXS Illumina HiSeq 76 63 153 0 ENST00000070846.6:c.603G>A p.Gly201= p.G201= ENST00000070846 NM_004572.3 201 ggG/ggA 0 +RAPGEF4 UCSF GRCh37 2 173679042 173679042 + synonymous_variant Silent SNP G G A NOVEL P28_Pri Untested WXS Illumina HiSeq 204 147 299 1 ENST00000397081.3:c.333G>A p.Thr111= p.T111= ENST00000397081 NM_007023.3 111 acG/acA 0 +SLC18A2 UCSF GRCh37 10 119026521 119026521 + missense_variant Missense_Mutation SNP T T C NOVEL P28_Pri Untested WXS Illumina HiSeq 117 75 190 0 ENST00000298472.5:c.1097T>C p.Ile366Thr p.I366T ENST00000298472 NM_003054.4 366 aTa/aCa 0 +SPATA5 UCSF GRCh37 4 123848842 123848842 + missense_variant Missense_Mutation SNP A A T NOVEL P28_Pri Untested WXS Illumina HiSeq 168 123 296 0 ENST00000274008.4:c.217A>T p.Asn73Tyr p.N73Y ENST00000274008 NM_145207.2 73 Aac/Tac 0 +THAP5 UCSF GRCh37 7 108205526 108205526 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P28_Pri Untested WXS Illumina HiSeq 7 0 ENST00000415914.3:c.297delA p.Lys99AsnfsTer25 p.K99Nfs*25 ENST00000415914 NM_001130475.1 99 aaA/aa 0 +TP53 UCSF GRCh37 17 7578541 7578541 + missense_variant Missense_Mutation SNP A A C NOVEL P28_Pri Untested WXS Illumina HiSeq 11 63 74 0 ENST00000269305.4:c.389T>G p.Leu130Arg p.L130R ENST00000269305 NM_001126112.2 130 cTc/cGc 0 +AMPD1 UCSF GRCh37 1 115222309 115222309 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 48 36 81 0 ENST00000520113.2:c.887G>A p.Arg296His p.R296H ENST00000520113 296 cGc/cAc 0 +AMZ2 UCSF GRCh37 17 66250631 66250631 + missense_variant Missense_Mutation SNP T T C NOVEL P28_Rec Untested WXS Illumina HiSeq 148 76 171 0 ENST00000359904.3:c.673T>C p.Ser225Pro p.S225P ENST00000359904 NM_016627.4 225 Tct/Cct 0 +ARSI UCSF GRCh37 5 149677736 149677736 + missense_variant Missense_Mutation SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 81 76 145 0 ENST00000328668.7:c.751C>T p.Arg251Cys p.R251C ENST00000328668 NM_001012301.2 251 Cgc/Tgc 0 +ATRX UCSF GRCh37 X 76937611 76937615 + frameshift_variant Frame_Shift_Del DEL CTTTT CTTTT - NOVEL P28_Rec Untested WXS Illumina HiSeq 198 0 ENST00000373344.5:c.3133_3137delAAAAG p.Lys1045Ter p.K1045* ENST00000373344 NM_000489.3 1045 AAAAGt/t 0 +CPNE2 UCSF GRCh37 16 57180218 57180218 + synonymous_variant Silent SNP T T C NOVEL P28_Rec Untested WXS Illumina HiSeq 254 29 189 0 ENST00000290776.8:c.1524T>C p.Phe508= p.F508= ENST00000290776 NM_152727.5 508 ttT/ttC 0 +CYB5D2 UCSF GRCh37 17 4053185 4053185 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 28 27 50 0 ENST00000301391.3:c.251G>A p.Gly84Asp p.G84D ENST00000301391 NM_144611.3 84 gGc/gAc 0 +DENND2D UCSF GRCh37 1 111741364 111741364 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 85 10 87 0 ENST00000357640.4:c.244C>T p.Arg82Trp p.R82W ENST00000357640 NM_024901.4 82 Cgg/Tgg 0 +DNMT1 UCSF GRCh37 19 10262139 10262139 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P28_Rec Untested WXS Illumina HiSeq 8 0 ENST00000340748.4:c.2152delA p.Met718CysfsTer59 p.M718Cfs*59 ENST00000340748 718 Atg/tg 0 +FZR1 UCSF GRCh37 19 3533340 3533340 + missense_variant Missense_Mutation SNP C C G NOVEL P28_Rec Untested WXS Illumina HiSeq 107 30 72 0 ENST00000395095.3:c.1291C>G p.Pro431Ala p.P431A ENST00000395095 NM_001136198.1 431 Ccc/Gcc 0 +GCN1L1 UCSF GRCh37 12 120612953 120612984 + splice_donor_variant,coding_sequence_variant,intron_variant Splice_Site DEL GAAATCCTATACCTGAGAGGACGCTCATCTTC GAAATCCTATACCTGAGAGGACGCTCATCTTC AAATCCTATACCTGGGAGGACGCTCATCTTT NOVEL P28_Rec Untested WXS Illumina HiSeq 7 0 ENST00000300648.6:c.1074_1093+12delinsAAAGATGAGCGTCCTCCCAGGTATAGGATTT p.X358_splice ENST00000300648 NM_006836.1 358 0 +GPR98 UCSF GRCh37 5 90085648 90085648 + missense_variant Missense_Mutation SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 31 18 41 0 ENST00000405460.2:c.14023G>A p.Gly4675Ser p.G4675S ENST00000405460 NM_032119.3 4675 Ggc/Agc 0 +HNRNPCL1 UCSF GRCh37 1 12907762 12907762 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.028,1000g2011may_all_0.0727,snp132_rs57026768 P28_Rec Untested WXS Illumina HiSeq 16 4 23 1 ENST00000317869.6:c.381A>G p.Pro127= p.P127= ENST00000317869 NM_001013631.1 127 ccA/ccG 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 8 16 24 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LOXHD1 UCSF GRCh37 18 44152078 44152078 + missense_variant Missense_Mutation SNP A A G NOVEL P28_Rec Untested WXS Illumina HiSeq 96 72 165 0 ENST00000398722.4:c.1184T>C p.Leu395Pro p.L395P ENST00000398722 395 cTa/cCa 0 +MCM7 UCSF GRCh37 7 99697025 99697041 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL ACCTAAAGGAGAAGAAC ACCTAAAGGAGAAGAAC CCCAAAAGGAAAAAAA NOVEL P28_Rec Untested WXS Illumina HiSeq 6 0 ENST00000303887.5:c.277-15_278delinsTTTTTTTCCTTTTGGG p.X93_splice ENST00000303887 NM_001278595.1 0 +MICAL2 UCSF GRCh37 11 12263921 12263921 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 98 51 138 0 ENST00000256194.4:c.2498C>T p.Ala833Val p.A833V ENST00000256194 NM_014632.2 833 gCg/gTg 0 +NMT2 UCSF GRCh37 10 15172208 15172208 + missense_variant Missense_Mutation SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 17 3 19 0 ENST00000378165.4:c.823C>A p.Leu275Met p.L275M ENST00000378165 NM_004808.2 275 Ctg/Atg 0 +PKP2 UCSF GRCh37 12 33031211 33031211 + synonymous_variant Silent SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 92 63 153 0 ENST00000070846.6:c.603G>A p.Gly201= p.G201= ENST00000070846 NM_004572.3 201 ggG/ggA 0 +POLA1 UCSF GRCh37 X 24833131 24833131 + missense_variant Missense_Mutation SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 21 3 23 0 ENST00000379059.3:c.3314G>T p.Arg1105Leu p.R1105L ENST00000379059 NM_016937.3 1105 cGg/cTg 0 +POLR3B UCSF GRCh37 12 106820973 106820987 + splice_acceptor_variant,coding_sequence_variant Splice_Site INS AGCTTTTATCTCTTC AGCTTTTATCTCTTC TAGCTTTTTTCTTTTT NOVEL P28_Rec Untested WXS Illumina HiSeq 6 0 ENST00000228347.4:c.1102-2_1114delinsTAGCTTTTTTCTTTTT p.X368_splice ENST00000228347 NM_018082.5 0 +RAPGEF4 UCSF GRCh37 2 173679042 173679042 + synonymous_variant Silent SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 202 158 299 1 ENST00000397081.3:c.333G>A p.Thr111= p.T111= ENST00000397081 NM_007023.3 111 acG/acA 0 +RHPN1 UCSF GRCh37 8 144460938 144460938 + synonymous_variant Silent SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 228 381 370 0 ENST00000289013.6:c.532C>T p.Leu178= p.L178= ENST00000289013 NM_052924.2 178 Ctg/Ttg 0 +RPL18 UCSF GRCh37 19 49119149 49119149 + missense_variant Missense_Mutation SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 24 3 42 0 ENST00000549920.1:c.476C>A p.Pro159Gln p.P159Q ENST00000549920 NM_000979.3 159 cCg/cAg 0 +SDK1 UCSF GRCh37 7 4304761 4304761 + synonymous_variant Silent SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 25 3 45 0 ENST00000404826.2:c.6387G>T p.Thr2129= p.T2129= ENST00000404826 NM_152744.3 2129 acG/acT 0 +SERPINB3 UCSF GRCh37 18 61326651 61326651 + synonymous_variant Silent SNP T T C NOVEL P28_Rec Untested WXS Illumina HiSeq 26 9 50 0 ENST00000283752.5:c.333A>G p.Lys111= p.K111= ENST00000283752 NM_006919.2 111 aaA/aaG 0 +SERPINI1 UCSF GRCh37 3 167508159 167508159 + splice_acceptor_variant Splice_Site SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 35 4 51 0 ENST00000295777.5:c.251-1G>T p.X84_splice ENST00000295777 NM_005025.4 0 +SLC18A2 UCSF GRCh37 10 119026521 119026521 + missense_variant Missense_Mutation SNP T T C NOVEL P28_Rec Untested WXS Illumina HiSeq 91 86 190 0 ENST00000298472.5:c.1097T>C p.Ile366Thr p.I366T ENST00000298472 NM_003054.4 366 aTa/aCa 0 +SPATA5 UCSF GRCh37 4 123848842 123848842 + missense_variant Missense_Mutation SNP A A T NOVEL P28_Rec Untested WXS Illumina HiSeq 180 146 296 0 ENST00000274008.4:c.217A>T p.Asn73Tyr p.N73Y ENST00000274008 NM_145207.2 73 Aac/Tac 0 +TCEAL3 UCSF GRCh37 X 102864442 102864442 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.02464 P28_Rec Untested WXS Illumina HiSeq 12 5 12 0 ENST00000243286.3:c.450A>G p.Gln150= p.Q150= ENST00000243286 NM_001006933.1 150 caA/caG 0 +TP53 UCSF GRCh37 17 7578541 7578541 + missense_variant Missense_Mutation SNP A A C NOVEL P28_Rec Untested WXS Illumina HiSeq 7 94 74 0 ENST00000269305.4:c.389T>G p.Leu130Arg p.L130R ENST00000269305 NM_001126112.2 130 cTc/cGc 0 +ADNP UCSF GRCh37 20 49508204 49508204 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P29_Pri Untested WXS Illumina HiSeq 7 0 ENST00000349014.3:c.3047delA p.Lys1016ArgfsTer11 p.K1016Rfs*11 ENST00000349014 NM_001282532.1 1016 aAg/ag 0 +AP2A1 UCSF GRCh37 19 50306222 50306222 + missense_variant Missense_Mutation SNP A A G NOVEL P29_Pri Untested WXS Illumina HiSeq 13 21 25 0 ENST00000359032.5:c.2197A>G p.Ile733Val p.I733V ENST00000359032 NM_014203.2 733 Atc/Gtc 0 +ATRX UCSF GRCh37 X 76813051 76813084 + frameshift_variant Frame_Shift_Del DEL AACAACTCGAAAAGACAGTGACTGCTTAGTTACT AACAACTCGAAAAGACAGTGACTGCTTAGTTACT - NOVEL P29_Pri Untested WXS Illumina HiSeq 33 0 ENST00000373344.5:c.6537_6570del p.Val2180IlefsTer11 p.V2180Ifs*11 ENST00000373344 NM_000489.3 2179 caAGTAACTAAGCAGTCACTGTCTTTTCGAGTTGTT/ca 0 +CAPN9 UCSF GRCh37 1 230903389 230903389 + synonymous_variant Silent SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 132 87 236 0 ENST00000271971.2:c.639C>T p.Pro213= p.P213= ENST00000271971 NM_006615.2 213 ccC/ccT 0 +CDC25B UCSF GRCh37 20 3785568 3785568 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 140 262 248 0 ENST00000245960.5:c.1703G>A p.Arg568Gln p.R568Q ENST00000245960 NM_021873.2 568 cGg/cAg 0 +COL4A4 UCSF GRCh37 2 227966580 227966580 + splice_donor_variant Splice_Site SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 83 45 138 0 ENST00000396625.3:c.975+1G>A p.X325_splice ENST00000396625 NM_000092.4 0 +CUX1 UCSF GRCh37 7 101892124 101892124 + synonymous_variant Silent SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 36 5 38 0 ENST00000292535.7:c.4320G>A p.Pro1440= p.P1440= ENST00000292535 NM_181552.3 1440 ccG/ccA 0 +DNAH5 UCSF GRCh37 5 13830849 13830849 + missense_variant Missense_Mutation SNP C C A NOVEL P29_Pri Untested WXS Illumina HiSeq 139 102 228 0 ENST00000265104.4:c.5918G>T p.Ser1973Ile p.S1973I ENST00000265104 NM_001369.2 1973 aGc/aTc 0 +DND1 UCSF GRCh37 5 140052430 140052430 + missense_variant Missense_Mutation SNP G G T 1000g2010nov_all_0.231,snp132_rs112925426 P29_Pri Untested WXS Illumina HiSeq 36 4 29 0 ENST00000542735.1:c.204C>A p.Asp68Glu p.D68E ENST00000542735 NM_194249.2 68 gaC/gaA 0 +DND1 UCSF GRCh37 5 140052424 140052424 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.301,snp132_rs72800921 P29_Pri Untested WXS Illumina HiSeq 35 4 27 1 ENST00000542735.1:c.210C>T p.Tyr70= p.Y70= ENST00000542735 NM_194249.2 70 taC/taT 0 +DPP6 UCSF GRCh37 7 153749963 153749963 + missense_variant Missense_Mutation SNP G G A snp132_rs2533731 P29_Pri Untested WXS Illumina HiSeq 17 4 9 0 ENST00000377770.3:c.58G>A p.Ala20Thr p.A20T ENST00000377770 20 Gcg/Acg 0 +EFTUD2 UCSF GRCh37 17 42937310 42937310 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 19 19 46 0 ENST00000426333.2:c.1823G>A p.Arg608His p.R608H ENST00000426333 NM_001142605.1 608 cGc/cAc 0 +EPHA8 UCSF GRCh37 1 22903034 22903034 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 164 164 301 0 ENST00000166244.3:c.484C>T p.Arg162Trp p.R162W ENST00000166244 NM_020526.3 162 Cgg/Tgg 0 +FAM114A1 UCSF GRCh37 4 38916617 38916617 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 119 64 205 0 ENST00000358869.2:c.868G>A p.Gly290Arg p.G290R ENST00000358869 NM_138389.2 290 Ggg/Agg 0 +FAM83H UCSF GRCh37 8 144808239 144808239 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 372 136 319 0 ENST00000388913.3:c.3392G>A p.Arg1131His p.R1131H ENST00000388913 NM_198488.3 1131 cGc/cAc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 11 18 20 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL1RL2 UCSF GRCh37 2 102851729 102851729 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 58 54 137 0 ENST00000264257.2:c.1670G>A p.Arg557His p.R557H ENST00000264257 NM_003854.2 557 cGc/cAc 0 +INTS1 UCSF GRCh37 7 1539622 1539622 + synonymous_variant Silent SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 69 62 151 0 ENST00000404767.3:c.582C>T p.Ile194= p.I194= ENST00000404767 NM_001080453.2 194 atC/atT 0 +KCND1 UCSF GRCh37 X 48826075 48826075 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 17 66 92 0 ENST00000218176.3:c.604G>A p.Ala202Thr p.A202T ENST00000218176 NM_004979.4 202 Gcc/Acc 0 +KEL UCSF GRCh37 7 142650990 142650990 + synonymous_variant Silent SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 286 105 275 0 ENST00000355265.2:c.978G>A p.Pro326= p.P326= ENST00000355265 NM_000420.2 326 ccG/ccA 0 +KIAA1267 UCSF GRCh37 17 44249468 44249469 + protein_altering_variant In_Frame_Ins INS - - TGA NOVEL P29_Pri Untested WXS Illumina HiSeq 31 0 ENST00000574590.1:c.41_42insTCA p.Glu14delinsAspGln p.E14delinsDQ ENST00000574590 NM_001193465.1 14 gaa/gaTCAa 0 +KRT15 UCSF GRCh37 17 39673204 39673204 + missense_variant Missense_Mutation SNP C C A NOVEL P29_Pri Untested WXS Illumina HiSeq 34 31 67 0 ENST00000254043.3:c.594G>T p.Glu198Asp p.E198D ENST00000254043 NM_002275.3 198 gaG/gaT 0 +LAMB1 UCSF GRCh37 7 107626783 107626783 + missense_variant Missense_Mutation SNP A A T NOVEL P29_Pri Untested WXS Illumina HiSeq 182 120 291 0 ENST00000222399.6:c.449T>A p.Ile150Lys p.I150K ENST00000222399 NM_002291.2 150 aTa/aAa 0 +MEIS2 UCSF GRCh37 15 37376018 37376018 + synonymous_variant Silent SNP G G C NOVEL P29_Pri Untested WXS Illumina HiSeq 104 61 130 0 ENST00000561208.1:c.708C>G p.Ser236= p.S236= ENST00000561208 236 tcC/tcG 0 +MRVI1 UCSF GRCh37 11 10625991 10625991 + missense_variant Missense_Mutation SNP G G C NOVEL P29_Pri Untested WXS Illumina HiSeq 25 14 39 0 ENST00000423302.2:c.1704C>G p.Asn568Lys p.N568K ENST00000423302 NM_130385.3 568 aaC/aaG 0 +OR7C1 UCSF GRCh37 19 14910208 14910208 + synonymous_variant Silent SNP C C A NOVEL P29_Pri Untested WXS Illumina HiSeq 88 57 173 0 ENST00000248073.2:c.741G>T p.Val247= p.V247= ENST00000248073 NM_198944.1 247 gtG/gtT 0 +PIK3CG UCSF GRCh37 7 106509501 106509501 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 197 143 383 0 ENST00000359195.3:c.1495G>A p.Ala499Thr p.A499T ENST00000359195 NM_002649.2 499 Gct/Act 0 +POLL UCSF GRCh37 10 103345866 103345866 + stop_gained Nonsense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 17 11 27 0 ENST00000299206.4:c.163C>T p.Arg55Ter p.R55* ENST00000299206 55 Cga/Tga 0 +POLR1A UCSF GRCh37 2 86260786 86260786 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 1 15 22 0 ENST00000263857.6:c.4159C>T p.Arg1387Trp p.R1387W ENST00000263857 1387 Cgg/Tgg 0 +PSMD13 UCSF GRCh37 11 251848 251848 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 69 48 122 0 ENST00000532097.1:c.947C>T p.Ser316Leu p.S316L ENST00000532097 NM_002817.3 316 tCg/tTg 0 +RETNLB UCSF GRCh37 3 108474653 108474653 + missense_variant Missense_Mutation SNP G G T NOVEL P29_Pri Untested WXS Illumina HiSeq 107 45 152 0 ENST00000295755.6:c.308C>A p.Thr103Asn p.T103N ENST00000295755 NM_032579.2 103 aCc/aAc 0 +RIN3 UCSF GRCh37 14 93118725 93118725 + missense_variant Missense_Mutation SNP A A G NOVEL P29_Pri Untested WXS Illumina HiSeq 36 29 68 0 ENST00000216487.7:c.1331A>G p.His444Arg p.H444R ENST00000216487 NM_024832.3 444 cAc/cGc 0 +RNF167 UCSF GRCh37 17 4846190 4846190 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 17 182 216 0 ENST00000262482.6:c.424G>A p.Glu142Lys p.E142K ENST00000262482 NM_015528.1 142 Gag/Aag 0 +RYK UCSF GRCh37 3 133928607 133928607 + missense_variant Missense_Mutation SNP T T C NOVEL P29_Pri Untested WXS Illumina HiSeq 77 44 113 0 ENST00000296084.4:c.515A>G p.Asn172Ser p.N172S ENST00000296084 NM_001005861.2 172 aAc/aGc 0 +STAG2 UCSF GRCh37 X 123200019 123200060 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TTACAGTGCCCATGACCTTTCAAAGTGGGATTTATTTGCTTG TTACAGTGCCCATGACCTTTCAAAGTGGGATTTATTTGCTTG ACAGGGCCCATGCCCTTTCAAAGGGGGATTTTTTTTTTTT NOVEL P29_Pri Untested WXS Illumina HiSeq 6 0 ENST00000371144.3:c.2097-6_2132delinsACAGGGCCCATGCCCTTTCAAAGGGGGATTTTTTTTTTTT p.X699_splice ENST00000371144 NM_001042751.1 0 +TEX11 UCSF GRCh37 X 69849501 69849501 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 10 100 149 0 ENST00000344304.3:c.1613C>T p.Pro538Leu p.P538L ENST00000344304 538 cCt/cTt 0 +THEG UCSF GRCh37 19 367122 367122 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 34 44 91 0 ENST00000342640.4:c.856C>T p.Pro286Ser p.P286S ENST00000342640 NM_016585.4 286 Ccc/Tcc 0 +TMCC3 UCSF GRCh37 12 94975905 94975905 + missense_variant Missense_Mutation SNP A A T NOVEL P29_Pri Untested WXS Illumina HiSeq 194 112 329 0 ENST00000261226.4:c.488T>A p.Ile163Lys p.I163K ENST00000261226 NM_020698.2 163 aTa/aAa 0 +TMEM176A UCSF GRCh37 7 150498790 150498790 + missense_variant Missense_Mutation SNP G G T NOVEL P29_Pri Untested WXS Illumina HiSeq 43 12 22 0 ENST00000004103.3:c.152G>T p.Ser51Ile p.S51I ENST00000004103 NM_018487.2 51 aGc/aTc 0 +TMTC4 UCSF GRCh37 13 101320994 101320994 + start_lost Translation_Start_Site SNP T T C NOVEL P29_Pri Untested WXS Illumina HiSeq 15 16 37 0 ENST00000376234.3:c.1A>G p.Met1? p.M1? ENST00000376234 NM_001079669.1 1 Atg/Gtg 0 +TP53 UCSF GRCh37 17 7577115 7577115 + missense_variant Missense_Mutation SNP A A G NOVEL P29_Pri Untested WXS Illumina HiSeq 6 101 153 0 ENST00000269305.4:c.823T>C p.Cys275Arg p.C275R ENST00000269305 NM_001126112.2 275 Tgt/Cgt 0 +ZNF236 UCSF GRCh37 18 74625704 74625704 + missense_variant,splice_region_variant Missense_Mutation SNP T T A NOVEL P29_Pri Untested WXS Illumina HiSeq 189 108 325 0 ENST00000253159.8:c.2905T>A p.Cys969Ser p.C969S ENST00000253159 NM_007345.3 969 Tgt/Agt 0 +ZNF394 UCSF GRCh37 7 99097486 99097486 + synonymous_variant Silent SNP T T C NOVEL P29_Pri Untested WXS Illumina HiSeq 75 58 138 0 ENST00000337673.6:c.231A>G p.Gly77= p.G77= ENST00000337673 NM_032164.2 77 ggA/ggG 0 +ADNP UCSF GRCh37 20 49508204 49508204 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P29_Rec Untested WXS Illumina HiSeq 6 0 ENST00000349014.3:c.3047delA p.Lys1016ArgfsTer11 p.K1016Rfs*11 ENST00000349014 NM_001282532.1 1016 aAg/ag 0 +AHNAK2 UCSF GRCh37 14 105413143 105413143 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.044 P29_Rec Untested WXS Illumina HiSeq 11 3 14 0 ENST00000333244.5:c.8645C>T p.Pro2882Leu p.P2882L ENST00000333244 NM_138420.2 2882 cCa/cTa 0 +AHNAK2 UCSF GRCh37 14 105413142 105413142 + synonymous_variant Silent SNP T T C NOVEL P29_Rec Untested WXS Illumina HiSeq 11 3 13 0 ENST00000333244.5:c.8646A>G p.Pro2882= p.P2882= ENST00000333244 NM_138420.2 2882 ccA/ccG 0 +APBA1 UCSF GRCh37 9 72067044 72067045 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P29_Rec Untested WXS Illumina HiSeq 15 0 ENST00000265381.4:c.1961_1962del p.Cys654Ter p.C654* ENST00000265381 NM_001163.3 654 tGT/t 0 +ATRX UCSF GRCh37 X 76813051 76813084 + frameshift_variant Frame_Shift_Del DEL AACAACTCGAAAAGACAGTGACTGCTTAGTTACT AACAACTCGAAAAGACAGTGACTGCTTAGTTACT - NOVEL P29_Rec Untested WXS Illumina HiSeq 28 0 ENST00000373344.5:c.6537_6570del p.Val2180IlefsTer11 p.V2180Ifs*11 ENST00000373344 NM_000489.3 2179 caAGTAACTAAGCAGTCACTGTCTTTTCGAGTTGTT/ca 0 +C16orf73 UCSF GRCh37 16 1884364 1884364 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 200 40 131 0 ENST00000397344.3:c.1222G>A p.Val408Ile p.V408I ENST00000397344 NM_152764.2 408 Gtt/Att 0 +C20orf107 UCSF GRCh37 20 55108415 55108415 + synonymous_variant Silent SNP G G T NOVEL P29_Rec Untested WXS Illumina HiSeq 251 51 238 0 ENST00000371325.1:c.18G>T p.Ser6= p.S6= ENST00000371325 NM_001013646.3 6 tcG/tcT 0 +C6orf165 UCSF GRCh37 6 88144700 88144700 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P29_Rec Untested WXS Illumina HiSeq 6 0 ENST00000369562.4:c.1430delA p.Asn477IlefsTer4 p.N477Ifs*4 ENST00000369562 NM_001031743.2 475 Aaa/aa 0 +C6orf89 UCSF GRCh37 6 36867371 36867371 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P29_Rec Untested WXS Illumina HiSeq 6 0 ENST00000373685.1:c.158delC p.Pro53ArgfsTer7 p.P53Rfs*7 ENST00000373685 51 Ccc/cc 0 +CDC25B UCSF GRCh37 20 3785568 3785568 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 271 214 248 0 ENST00000245960.5:c.1703G>A p.Arg568Gln p.R568Q ENST00000245960 NM_021873.2 568 cGg/cAg 0 +COL4A4 UCSF GRCh37 2 227966580 227966580 + splice_donor_variant Splice_Site SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 121 54 138 0 ENST00000396625.3:c.975+1G>A p.X325_splice ENST00000396625 NM_000092.4 0 +DNAH5 UCSF GRCh37 5 13830849 13830849 + missense_variant Missense_Mutation SNP C C A NOVEL P29_Rec Untested WXS Illumina HiSeq 230 94 228 0 ENST00000265104.4:c.5918G>T p.Ser1973Ile p.S1973I ENST00000265104 NM_001369.2 1973 aGc/aTc 0 +DND1 UCSF GRCh37 5 140052430 140052430 + missense_variant Missense_Mutation SNP G G T 1000g2010nov_all_0.231,snp132_rs112925426 P29_Rec Untested WXS Illumina HiSeq 47 6 29 0 ENST00000542735.1:c.204C>A p.Asp68Glu p.D68E ENST00000542735 NM_194249.2 68 gaC/gaA 0 +DND1 UCSF GRCh37 5 140052424 140052424 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.301,snp132_rs72800921 P29_Rec Untested WXS Illumina HiSeq 42 6 27 1 ENST00000542735.1:c.210C>T p.Tyr70= p.Y70= ENST00000542735 NM_194249.2 70 taC/taT 0 +EFTUD2 UCSF GRCh37 17 42937310 42937310 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 38 24 46 0 ENST00000426333.2:c.1823G>A p.Arg608His p.R608H ENST00000426333 NM_001142605.1 608 cGc/cAc 0 +EPHA8 UCSF GRCh37 1 22903034 22903034 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 262 130 301 0 ENST00000166244.3:c.484C>T p.Arg162Trp p.R162W ENST00000166244 NM_020526.3 162 Cgg/Tgg 0 +FAM83H UCSF GRCh37 8 144808239 144808239 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 197 154 319 0 ENST00000388913.3:c.3392G>A p.Arg1131His p.R1131H ENST00000388913 NM_198488.3 1131 cGc/cAc 0 +GAS2 UCSF GRCh37 11 22707300 22707300 + missense_variant Missense_Mutation SNP T T C NOVEL P29_Rec Untested WXS Illumina HiSeq 97 30 75 0 ENST00000278187.3:c.232T>C p.Phe78Leu p.F78L ENST00000278187 NM_177553.2 78 Ttc/Ctc 0 +HERC2 UCSF GRCh37 15 28419659 28419659 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.004,1000g2011may_all_0.0126,snp132_rs117437554 P29_Rec Untested WXS Illumina HiSeq 23 5 18 0 ENST00000261609.7:c.9939C>T p.Arg3313= p.R3313= ENST00000261609 NM_004667.5 3313 cgC/cgT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 27 10 20 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL1RL2 UCSF GRCh37 2 102851729 102851729 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 101 46 137 0 ENST00000264257.2:c.1670G>A p.Arg557His p.R557H ENST00000264257 NM_003854.2 557 cGc/cAc 0 +INTS1 UCSF GRCh37 7 1539622 1539622 + synonymous_variant Silent SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 131 68 151 0 ENST00000404767.3:c.582C>T p.Ile194= p.I194= ENST00000404767 NM_001080453.2 194 atC/atT 0 +KIAA1267 UCSF GRCh37 17 44249468 44249469 + protein_altering_variant In_Frame_Ins INS - - TGA NOVEL P29_Rec Untested WXS Illumina HiSeq 19 0 ENST00000574590.1:c.41_42insTCA p.Glu14delinsAspGln p.E14delinsDQ ENST00000574590 NM_001193465.1 14 gaa/gaTCAa 0 +KRT15 UCSF GRCh37 17 39673204 39673204 + missense_variant Missense_Mutation SNP C C A NOVEL P29_Rec Untested WXS Illumina HiSeq 57 19 67 0 ENST00000254043.3:c.594G>T p.Glu198Asp p.E198D ENST00000254043 NM_002275.3 198 gaG/gaT 0 +KRTAP5-1 UCSF GRCh37 11 1605979 1605979 + synonymous_variant Silent SNP A A G snp132_rs59646474 P29_Rec Untested WXS Illumina HiSeq 12 3 12 0 ENST00000382171.2:c.501T>C p.Cys167= p.C167= ENST00000382171 NM_001005922.1 167 tgT/tgC 0 +MEIS2 UCSF GRCh37 15 37376018 37376018 + synonymous_variant Silent SNP G G C NOVEL P29_Rec Untested WXS Illumina HiSeq 129 70 130 0 ENST00000561208.1:c.708C>G p.Ser236= p.S236= ENST00000561208 236 tcC/tcG 0 +MRVI1 UCSF GRCh37 11 10625991 10625991 + missense_variant Missense_Mutation SNP G G C NOVEL P29_Rec Untested WXS Illumina HiSeq 50 14 39 0 ENST00000423302.2:c.1704C>G p.Asn568Lys p.N568K ENST00000423302 NM_130385.3 568 aaC/aaG 0 +OBSCN UCSF GRCh37 1 228467634 228467634 + missense_variant Missense_Mutation SNP G G C NOVEL P29_Rec Untested WXS Illumina HiSeq 353 65 324 0 ENST00000422127.1:c.7509G>C p.Lys2503Asn p.K2503N ENST00000422127 NM_001098623.2 2503 aaG/aaC 0 +OR7C1 UCSF GRCh37 19 14910208 14910208 + synonymous_variant Silent SNP C C A NOVEL P29_Rec Untested WXS Illumina HiSeq 144 68 173 0 ENST00000248073.2:c.741G>T p.Val247= p.V247= ENST00000248073 NM_198944.1 247 gtG/gtT 0 +PIK3CG UCSF GRCh37 7 106509501 106509501 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 443 130 383 0 ENST00000359195.3:c.1495G>A p.Ala499Thr p.A499T ENST00000359195 NM_002649.2 499 Gct/Act 0 +POLR1A UCSF GRCh37 2 86260786 86260786 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 23 12 22 0 ENST00000263857.6:c.4159C>T p.Arg1387Trp p.R1387W ENST00000263857 1387 Cgg/Tgg 0 +POM121 UCSF GRCh37 7 72413581 72413581 + missense_variant Missense_Mutation SNP G G A snp132_rs71554687 P29_Rec Untested WXS Illumina HiSeq 24 5 10 0 ENST00000434423.2:c.3049G>A p.Val1017Ile p.V1017I ENST00000434423 1017 Gtc/Atc 0 +POM121 UCSF GRCh37 7 72413593 72413593 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.170,snp132_rs71554688 P29_Rec Untested WXS Illumina HiSeq 24 5 11 0 ENST00000434423.2:c.3061T>C p.Tyr1021His p.Y1021H ENST00000434423 1021 Tac/Cac 0 +PSMD13 UCSF GRCh37 11 251848 251848 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 118 52 122 0 ENST00000532097.1:c.947C>T p.Ser316Leu p.S316L ENST00000532097 NM_002817.3 316 tCg/tTg 0 +PTGIR UCSF GRCh37 19 47127054 47127054 + missense_variant Missense_Mutation SNP G G C NOVEL P29_Rec Untested WXS Illumina HiSeq 36 14 53 0 ENST00000291294.2:c.429C>G p.Ile143Met p.I143M ENST00000291294 NM_000960.3 143 atC/atG 0 +RBBP7 UCSF GRCh37 X 16870935 16870935 + missense_variant Missense_Mutation SNP T T G NOVEL P29_Rec Untested WXS Illumina HiSeq 24 10 36 0 ENST00000380087.2:c.822A>C p.Glu274Asp p.E274D ENST00000380087 274 gaA/gaC 0 +RNF167 UCSF GRCh37 17 4846190 4846190 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 122 163 216 0 ENST00000262482.6:c.424G>A p.Glu142Lys p.E142K ENST00000262482 NM_015528.1 142 Gag/Aag 0 +SGOL1 UCSF GRCh37 3 20216031 20216031 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 596 121 449 0 ENST00000263753.4:c.992C>T p.Ser331Phe p.S331F ENST00000263753 NM_001012410.3 331 tCc/tTc 0 +SMARCAD1 UCSF GRCh37 4 95197556 95197556 + synonymous_variant Silent SNP A A G NOVEL P29_Rec Untested WXS Illumina HiSeq 267 42 253 0 ENST00000354268.4:c.1875A>G p.Ala625= p.A625= ENST00000354268 625 gcA/gcG 0 +TBC1D3G UCSF GRCh37 17 34797608 34797608 + missense_variant Missense_Mutation SNP T T C NOVEL P29_Rec Untested WXS Illumina HiSeq 12 4 22 1 ENST00000341264.6:c.1528A>G p.Ser510Gly p.S510G ENST00000341264 NM_001040282.2 510 Agc/Ggc 0 +TCHH UCSF GRCh37 1 152086556 152086557 + upstream_gene_variant 5'Flank INS - - TT NOVEL P29_Rec Untested WXS Illumina HiSeq 18 0 ENST00000368804 NM_007113.3 0 +TEX11 UCSF GRCh37 X 69849501 69849501 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 78 80 149 0 ENST00000344304.3:c.1613C>T p.Pro538Leu p.P538L ENST00000344304 538 cCt/cTt 0 +THEG UCSF GRCh37 19 367122 367122 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 84 27 91 0 ENST00000342640.4:c.856C>T p.Pro286Ser p.P286S ENST00000342640 NM_016585.4 286 Ccc/Tcc 0 +TMTC4 UCSF GRCh37 13 101320994 101320994 + start_lost Translation_Start_Site SNP T T C NOVEL P29_Rec Untested WXS Illumina HiSeq 31 23 37 0 ENST00000376234.3:c.1A>G p.Met1? p.M1? ENST00000376234 NM_001079669.1 1 Atg/Gtg 0 +TP53 UCSF GRCh37 17 7577115 7577115 + missense_variant Missense_Mutation SNP A A G NOVEL P29_Rec Untested WXS Illumina HiSeq 91 105 153 0 ENST00000269305.4:c.823T>C p.Cys275Arg p.C275R ENST00000269305 NM_001126112.2 275 Tgt/Cgt 0 +XPC UCSF GRCh37 3 14219966 14219968 + inframe_deletion,splice_region_variant In_Frame_Del DEL CCT CCT - 1000g2010nov_all P29_Rec Untested WXS Illumina HiSeq 6 0 ENST00000285021.7:c.101_103delAGG p.Glu34del p.E34del ENST00000285021 NM_004628.4 34 gAGGat/gat 0 +ZNF394 UCSF GRCh37 7 99097486 99097486 + synonymous_variant Silent SNP T T C NOVEL P29_Rec Untested WXS Illumina HiSeq 204 82 138 0 ENST00000337673.6:c.231A>G p.Gly77= p.G77= ENST00000337673 NM_032164.2 77 ggA/ggG 0 diff --git a/end-to-end-test/local/studies/lgg_ucsf_2014_test_generic_assay/data_mutations_extended.txt.REMOVED.git-id b/end-to-end-test/local/studies/lgg_ucsf_2014_test_generic_assay/data_mutations_extended.txt.REMOVED.git-id deleted file mode 100644 index 1a7aeb92f60..00000000000 --- a/end-to-end-test/local/studies/lgg_ucsf_2014_test_generic_assay/data_mutations_extended.txt.REMOVED.git-id +++ /dev/null @@ -1 +0,0 @@ -12ba2798ce5da79a292865354d12da077dbf4370 \ No newline at end of file diff --git a/end-to-end-test/local/studies/lgg_ucsf_2014_test_generic_assay/data_mutations_mskcc.txt b/end-to-end-test/local/studies/lgg_ucsf_2014_test_generic_assay/data_mutations_mskcc.txt new file mode 100644 index 00000000000..a801aa89d9e --- /dev/null +++ b/end-to-end-test/local/studies/lgg_ucsf_2014_test_generic_assay/data_mutations_mskcc.txt @@ -0,0 +1,15156 @@ +Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Consequence Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer t_ref_count t_alt_count n_ref_count n_alt_count HGVSc HGVSp HGVSp_Short Transcript_ID RefSeq Protein_position Codons Hotspot +ANK2 UCSF GRCh37 4 114257011 114257011 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 27 5 40 1 ENST00000357077.4:c.3389G>A p.Ser1130Asn p.S1130N ENST00000357077 NM_001148.4 1130 aGc/aAc 0 +ATRX UCSF GRCh37 X 76938230 76938231 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Pri Untested WXS Illumina HiSeq 45 0 ENST00000373344.5:c.2518dup p.Arg840LysfsTer9 p.R840Kfs*9 ENST00000373344 NM_000489.3 839 -/A 0 +BCLAF1 UCSF GRCh37 6 136599392 136599392 + synonymous_variant Silent SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 151 31 206 0 ENST00000531224.1:c.627C>T p.Ser209= p.S209= ENST00000531224 NM_001077441.1 209 tcC/tcT 0 +BDP1 UCSF GRCh37 5 70811923 70811923 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 32 13 45 0 ENST00000358731.4:c.4685A>G p.Lys1562Arg p.K1562R ENST00000358731 NM_018429.2 1562 aAg/aGg 0 +BRIX1 UCSF GRCh37 5 34925341 34925341 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Pri Untested WXS Illumina HiSeq 20 6 31 0 ENST00000336767.5:c.803T>C p.Val268Ala p.V268A ENST00000336767 NM_018321.3 268 gTc/gCc 0 +CDHR5 UCSF GRCh37 11 618860 618860 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.029 P01_Pri Untested WXS Illumina HiSeq 21 3 24 1 ENST00000358353.3:c.1699A>G p.Ser567Gly p.S567G ENST00000358353 567 Agt/Ggt 0 +CES1 UCSF GRCh37 16 55862883 55862883 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.320,snp132_rs34380375 P01_Pri Untested WXS Illumina HiSeq 14 6 25 1 ENST00000360526.3:c.56G>T p.Gly19Val p.G19V ENST00000360526 NM_001266.4 19 gGg/gTg 0 +CHRM2 UCSF GRCh37 7 136701008 136701008 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 41 5 64 0 ENST00000445907.2:c.1396A>G p.Arg466Gly p.R466G ENST00000445907 NM_001006627.1 466 Agg/Ggg 0 +CNOT4 UCSF GRCh37 7 135122975 135122975 + stop_gained Nonsense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 40 6 48 1 ENST00000541284.1:c.105C>A p.Tyr35Ter p.Y35* ENST00000541284 NM_001190849.1 35 taC/taA 0 +DDR1 UCSF GRCh37 6 30864491 30864491 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 31 24 25 0 ENST00000376575.3:c.1718A>G p.Asp573Gly p.D573G ENST00000376575 573 gAc/gGc 0 +DLC1 UCSF GRCh37 8 12950182 12950182 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 21 6 37 0 ENST00000276297.4:c.3679G>A p.Val1227Met p.V1227M ENST00000276297 NM_182643.2 1227 Gtg/Atg 0 +ERBB2IP UCSF GRCh37 5 65371004 65371004 + synonymous_variant Silent SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 54 21 89 0 ENST00000506030.1:c.3930A>G p.Pro1310= p.P1310= ENST00000506030 1310 ccA/ccG 0 +FBXO18 UCSF GRCh37 10 5965617 5965617 + missense_variant Missense_Mutation SNP G G C NOVEL P01_Pri Untested WXS Illumina HiSeq 37 19 61 0 ENST00000379999.5:c.2509G>C p.Asp837His p.D837H ENST00000379999 NM_032807.4 837 Gat/Cat 0 +FYB UCSF GRCh37 5 39122471 39122471 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 31 5 52 1 ENST00000540520.1:c.2135C>A p.Thr712Asn p.T712N ENST00000540520 NM_001243093.1 712 aCc/aAc 0 +HGSNAT UCSF GRCh37 8 43046714 43046714 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Pri Untested WXS Illumina HiSeq 33 12 56 0 ENST00000379644.4:c.1226T>C p.Leu409Pro p.L409P ENST00000379644 NM_152419.2 409 cTc/cCc 0 +HLA-C UCSF GRCh37 6 31238897 31238897 + missense_variant Missense_Mutation SNP C C G NOVEL P01_Pri Untested WXS Illumina HiSeq 39 6 25 1 ENST00000376228.5:c.572G>C p.Trp191Ser p.W191S ENST00000376228 NM_002117.5 191 tGg/tCg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 40 21 74 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIF3C UCSF GRCh37 2 26204031 26204031 + synonymous_variant Silent SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 12 3 15 0 ENST00000264712.3:c.756G>A p.Arg252= p.R252= ENST00000264712 NM_002254.6 252 agG/agA 0 +KIR2DS4 UCSF GRCh37 19 55350964 55350965 + stop_gained,frameshift_variant Nonsense_Mutation INS - - CCCGGAGCTCCTATGACATGTA snp132_rs35757649 P01_Pri Untested WXS Illumina HiSeq 6 0 ENST00000339924.8:c.453_454insCCGGAGCTCCTATGACATGTAC p.Ile152ProfsTer5 p.I152Pfs*5 ENST00000339924 NM_001281971.1 151 tcc/tcCCCGGAGCTCCTATGACATGTAc 0 +LOXL4 UCSF GRCh37 10 100013411 100013411 + stop_gained Nonsense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 13 7 28 1 ENST00000260702.3:c.1734C>A p.Tyr578Ter p.Y578* ENST00000260702 NM_032211.6 578 taC/taA 0 +LTK UCSF GRCh37 15 41796420 41796420 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 12 4 22 0 ENST00000263800.6:c.2369T>C p.Leu790Pro p.L790P ENST00000263800 NM_002344.5 790 cTc/cCc 0 +MGAT4A UCSF GRCh37 2 99342774 99342774 + missense_variant Missense_Mutation SNP C C A snp132_rs79141144 P01_Pri Untested WXS Illumina HiSeq 28 4 35 1 ENST00000264968.3:c.22G>T p.Val8Leu p.V8L ENST00000264968 8 Gta/Tta 0 +MYH9 UCSF GRCh37 22 36717828 36717828 + stop_gained Nonsense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 29 5 36 0 ENST00000216181.5:c.744C>A p.Tyr248Ter p.Y248* ENST00000216181 NM_002473.4 248 taC/taA 0 +MYOCD UCSF GRCh37 17 12666467 12666467 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 45 23 77 0 ENST00000425538.1:c.2467A>G p.Thr823Ala p.T823A ENST00000425538 NM_001146312.1 823 Act/Gct 0 +MYOCD UCSF GRCh37 17 12620673 12620673 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 17 4 58 0 ENST00000425538.1:c.188C>T p.Ser63Phe p.S63F ENST00000425538 NM_001146312.1 63 tCc/tTc 0 +NUDT10 UCSF GRCh37 X 51076024 51076024 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.00397,1000g2011may_all_0.0126,snp132_rs2801626 P01_Pri Untested WXS Illumina HiSeq 13 3 10 0 ENST00000376006.3:c.207G>A p.Glu69= p.E69= ENST00000376006 NM_153183.2 69 gaG/gaA 0 +OR7C2 UCSF GRCh37 19 15052698 15052698 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 70 38 127 0 ENST00000248072.3:c.398C>T p.Thr133Met p.T133M ENST00000248072 NM_012377.1 133 aCg/aTg 0 +OVOL2 UCSF GRCh37 20 18005411 18005411 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 23 7 38 0 ENST00000278780.6:c.697G>A p.Val233Met p.V233M ENST00000278780 NM_021220.2 233 Gtg/Atg 0 +PRB1 UCSF GRCh37 12 11506582 11506582 + intron_variant Intron SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 41 6 35 1 ENST00000500254.2:c.313+142G>A *105* ENST00000500254 NM_199353.2 0 +PRKAB1 UCSF GRCh37 12 120114413 120114413 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 31 17 51 0 ENST00000229328.5:c.604G>A p.Ala202Thr p.A202T ENST00000229328 NM_006253.4 202 Gca/Aca 0 +PSG7 UCSF GRCh37 19 43430146 43430146 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 113 14 150 0 ENST00000406070.2:c.1022T>C p.Phe341Ser p.F341S ENST00000406070 NM_002783.2 341 tTc/tCc 0 +PSMD13 UCSF GRCh37 11 248855 248855 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Pri Untested WXS Illumina HiSeq 24 12 45 0 ENST00000431206.2:c.654C>T p.Leu218= p.L218= ENST00000431206 NM_175932.2 218 ctC/ctT 0 +RALGAPB UCSF GRCh37 20 37150153 37150153 + synonymous_variant Silent SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 74 36 102 0 ENST00000262879.6:c.1431A>G p.Gln477= p.Q477= ENST00000262879 477 caA/caG 0 +SERPINE1 UCSF GRCh37 7 100773852 100773852 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 85 32 105 0 ENST00000223095.4:c.422G>A p.Arg141Gln p.R141Q ENST00000223095 NM_000602.4 141 cGg/cAg 0 +SMPD4 UCSF GRCh37 2 130912789 130912789 + missense_variant Missense_Mutation SNP A A C NOVEL P01_Pri Untested WXS Illumina HiSeq 14 4 14 0 ENST00000409031.1:c.1450T>G p.Phe484Val p.F484V ENST00000409031 NM_017951.4 484 Ttt/Gtt 0 +SMPD4 UCSF GRCh37 2 130912778 130912778 + synonymous_variant Silent SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 15 4 15 0 ENST00000409031.1:c.1461T>C p.Phe487= p.F487= ENST00000409031 NM_017951.4 487 ttT/ttC 0 +SRRM2 UCSF GRCh37 16 2807494 2807494 + synonymous_variant Silent SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 40 13 59 0 ENST00000301740.8:c.264G>A p.Gln88= p.Q88= ENST00000301740 NM_016333.3 88 caG/caA 0 +TEX11 UCSF GRCh37 X 69749812 69749812 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri Untested WXS Illumina HiSeq 14 16 41 0 ENST00000395889.2:c.2603T>C p.Val868Ala p.V868A ENST00000395889 NM_001003811.1 868 gTc/gCc 0 +TMPRSS15 UCSF GRCh37 21 19666630 19666630 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 34 8 44 0 ENST00000284885.3:c.2443G>A p.Val815Ile p.V815I ENST00000284885 NM_002772.2 815 Gtc/Atc 0 +TP53 UCSF GRCh37 17 7578527 7578527 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 14 4 15 0 ENST00000269305.4:c.403T>C p.Cys135Arg p.C135R ENST00000269305 NM_001126112.2 135 Tgc/Cgc 0 +TP53 UCSF GRCh37 17 7579310 7579310 + splice_donor_variant Splice_Site SNP A A C NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 24 9 55 0 ENST00000269305.4:c.375+2T>G p.X125_splice ENST00000269305 NM_001126112.2 0 +TPR UCSF GRCh37 1 186301466 186301466 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Pri Untested WXS Illumina HiSeq 32 8 58 0 ENST00000367478.4:c.5465C>A p.Thr1822Asn p.T1822N ENST00000367478 NM_003292.2 1822 aCc/aAc 0 +TRIM33 UCSF GRCh37 1 114967346 114967346 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 28 15 59 0 ENST00000358465.2:c.1727A>G p.Gln576Arg p.Q576R ENST00000358465 NM_015906.3 576 cAa/cGa 0 +TYW1B UCSF GRCh37 7 72093896 72093896 + missense_variant Missense_Mutation SNP C C T snp132_rs7776775 P01_Pri Untested WXS Illumina HiSeq 35 4 38 1 ENST00000435769.2:c.1594G>A p.Glu532Lys p.E532K ENST00000435769 NM_001145440.1 532 Gaa/Aaa 0 +VCAN UCSF GRCh37 5 82815180 82815180 + missense_variant Missense_Mutation SNP C C A NOVEL P01_Pri Untested WXS Illumina HiSeq 43 7 57 1 ENST00000265077.3:c.1055C>A p.Thr352Lys p.T352K ENST00000265077 NM_004385.4 352 aCa/aAa 0 +WBSCR17 UCSF GRCh37 7 71175875 71175875 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Pri Untested WXS Illumina HiSeq 10 5 19 0 ENST00000333538.5:c.1630G>A p.Val544Ile p.V544I ENST00000333538 NM_022479.2 544 Gtc/Atc 0 +ZNF598 UCSF GRCh37 16 2048796 2048796 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.086,1000g2011may_all_0.1651,snp132_rs1058474 P01_Pri Untested WXS Illumina HiSeq 8 7 8 0 ENST00000431526.1:c.2268G>A p.Arg756= p.R756= ENST00000431526 756 agG/agA 0 +ZNF616 UCSF GRCh37 19 52620039 52620039 + missense_variant Missense_Mutation SNP A A C NOVEL P01_Pri somatic WXS Sanger Illumina HiSeq 105 19 150 0 ENST00000600228.1:c.378T>G p.His126Gln p.H126Q ENST00000600228 NM_178523.3 126 caT/caG 0 +AADAT UCSF GRCh37 4 170989794 170989794 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 24 91 0 ENST00000337664.4:c.848G>A p.Arg283Lys p.R283K ENST00000337664 NM_016228.3 283 aGa/aAa 0 +AAK1 UCSF GRCh37 2 69746264 69746264 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 13 0 ENST00000409085.4:c.1319C>T p.Pro440Leu p.P440L ENST00000409085 NM_014911.3 440 cCc/cTc 0 +ABCA2 UCSF GRCh37 9 139914833 139914833 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 7 11 0 ENST00000341511.6:c.1380C>T p.Ile460= p.I460= ENST00000341511 NM_212533.2 460 atC/atT 0 +ABCA4 UCSF GRCh37 1 94548977 94548977 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 154 34 179 0 ENST00000370225.3:c.789C>T p.Ser263= p.S263= ENST00000370225 NM_000350.2 263 agC/agT 0 +ABCA8 UCSF GRCh37 17 66914202 66914202 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 22 43 0 ENST00000269080.2:c.1913C>T p.Ala638Val p.A638V ENST00000269080 NM_007168.2 638 gCc/gTc 0 +ABCC10 UCSF GRCh37 6 43415071 43415071 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 7 23 0 ENST00000372530.4:c.3630C>T p.Ala1210= p.A1210= ENST00000372530 NM_001198934.1 1210 gcC/gcT 0 +ABCC3 UCSF GRCh37 17 48733333 48733333 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 8 16 0 ENST00000285238.8:c.186C>T p.Gly62= p.G62= ENST00000285238 NM_003786.3 62 ggC/ggT 0 +ABCC6 UCSF GRCh37 16 16281014 16281014 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 5 17 0 ENST00000205557.7:c.1834C>T p.Pro612Ser p.P612S ENST00000205557 NM_001171.5 612 Cct/Tct 0 +ABCC6 UCSF GRCh37 16 16259656 16259656 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 7 50 0 ENST00000205557.7:c.3130C>T p.Leu1044= p.L1044= ENST00000205557 NM_001171.5 1044 Ctg/Ttg 0 +ABCF1 UCSF GRCh37 6 30552213 30552213 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 53 6 21 0 ENST00000326195.8:c.1261G>A p.Ala421Thr p.A421T ENST00000326195 NM_001025091.1 421 Gcc/Acc 0 +ABCG4 UCSF GRCh37 11 119025283 119025283 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 4 22 0 ENST00000307417.3:c.538C>T p.Leu180= p.L180= ENST00000307417 NM_022169.4 180 Ctg/Ttg 0 +ABHD1 UCSF GRCh37 2 27353277 27353277 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0014 P01_Rec Untested WXS Illumina HiSeq 61 59 95 0 ENST00000316470.4:c.999C>T p.Pro333= p.P333= ENST00000316470 NM_032604.3 333 ccC/ccT 0 +ABHD14A UCSF GRCh37 3 52011925 52011925 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0106,snp132_rs34991570 P01_Rec Untested WXS Illumina HiSeq 7 33 74 0 ENST00000273596.3:c.108C>T p.Ala36= p.A36= ENST00000273596 NM_015407.4 36 gcC/gcT 0 +ABI3BP UCSF GRCh37 3 100523699 100523699 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 31 54 0 ENST00000284322.5:c.1684C>T p.Pro562Ser p.P562S ENST00000284322 NM_015429.3 562 Ccc/Tcc 0 +ABRA UCSF GRCh37 8 107781939 107781939 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 75 9 46 0 ENST00000311955.3:c.480G>A p.Arg160= p.R160= ENST00000311955 NM_139166.4 160 agG/agA 0 +ACACB UCSF GRCh37 12 109671612 109671612 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 4 28 51 0 ENST00000338432.7:c.4199G>A p.Ser1400Asn p.S1400N ENST00000338432 1400 aGc/aAc 0 +ACADSB UCSF GRCh37 10 124804002 124804002 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 5 48 0 ENST00000358776.4:c.900+1G>A p.X300_splice ENST00000358776 NM_001609.3 0 +ACCN1 UCSF GRCh37 17 32483105 32483105 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 29 38 0 ENST00000359872.6:c.447G>A p.Lys149= p.K149= ENST00000359872 NM_001094.4 149 aaG/aaA 0 +ACCN2 UCSF GRCh37 12 50473742 50473742 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 18 40 0 ENST00000228468.4:c.1109C>T p.Thr370Ile p.T370I ENST00000228468 NM_020039.3 370 aCc/aTc 0 +ACCN2 UCSF GRCh37 12 50473707 50473707 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 9 56 0 ENST00000228468.4:c.1074G>A p.Gln358= p.Q358= ENST00000228468 NM_020039.3 358 caG/caA 0 +ACHE UCSF GRCh37 7 100490086 100490086 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 11 22 0 ENST00000302913.4:c.1422G>A p.Met474Ile p.M474I ENST00000302913 NM_015831.2 474 atG/atA 0 +ACHE UCSF GRCh37 7 100491439 100491439 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 9 30 0 ENST00000302913.4:c.415C>T p.Pro139Ser p.P139S ENST00000302913 NM_015831.2 139 Cct/Tct 0 +ACIN1 UCSF GRCh37 14 23564285 23564285 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 6 17 0 ENST00000262710.1:c.211C>T p.Pro71Ser p.P71S ENST00000262710 NM_001164814.1 71 Cct/Tct 0 +ACOT7 UCSF GRCh37 1 6399581 6399581 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 3 11 0 ENST00000377855.2:c.360G>A p.Glu120= p.E120= ENST00000377855 NM_181864.2 120 gaG/gaA 0 +ACOT7 UCSF GRCh37 1 6399629 6399629 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 5 14 0 ENST00000377855.2:c.312G>A p.Leu104= p.L104= ENST00000377855 NM_181864.2 104 ctG/ctA 0 +ACOX2 UCSF GRCh37 3 58514680 58514680 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 6 47 0 ENST00000302819.5:c.996C>T p.Asp332= p.D332= ENST00000302819 NM_003500.3 332 gaC/gaT 0 +ACSF2 UCSF GRCh37 17 48551629 48551629 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 24 44 0 ENST00000300441.4:c.1797+1G>A p.X599_splice ENST00000300441 NM_025149.4 0 +ACSM2A UCSF GRCh37 16 20482518 20482518 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 13 75 0 ENST00000573854.1:c.720C>T p.Leu240= p.L240= ENST00000573854 NM_001010845.2 240 ctC/ctT 0 +ACSS1 UCSF GRCh37 20 24988489 24988489 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 6 20 0 ENST00000323482.4:c.1979G>A p.Gly660Glu p.G660E ENST00000323482 NM_001252675.1 660 gGa/gAa 0 +ACTL9 UCSF GRCh37 19 8808284 8808284 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 8 9 0 ENST00000324436.3:c.768C>T p.His256= p.H256= ENST00000324436 NM_178525.3 256 caC/caT 0 +ACTR2 UCSF GRCh37 2 65478212 65478212 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 21 101 0 ENST00000377982.4:c.442G>A p.Val148Ile p.V148I ENST00000377982 NM_001005386.2 148 Gtt/Att 0 +ACY3 UCSF GRCh37 11 67410218 67410218 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 18 28 0 ENST00000255082.3:c.937C>T p.Pro313Ser p.P313S ENST00000255082 NM_080658.1 313 Cct/Tct 0 +ADAM10 UCSF GRCh37 15 58889799 58889799 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 35 61 0 ENST00000260408.3:c.2194C>T p.Pro732Ser p.P732S ENST00000260408 NM_001110.2 732 Ccc/Tcc 0 +ADAM11 UCSF GRCh37 17 42850761 42850761 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 16 11 14 0 ENST00000200557.6:c.958C>T p.Leu320= p.L320= ENST00000200557 NM_002390.4 320 Ctg/Ttg 0 +ADAM11 UCSF GRCh37 17 42854295 42854295 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 26 32 0 ENST00000200557.6:c.1646C>T p.Thr549Ile p.T549I ENST00000200557 NM_002390.4 549 aCc/aTc 0 +ADAM12 UCSF GRCh37 10 127824179 127824179 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 25 0 ENST00000368679.4:c.399C>T p.Val133= p.V133= ENST00000368679 NM_003474.4 133 gtC/gtT 0 +ADAMTS15 UCSF GRCh37 11 130331452 130331452 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 17 26 0 ENST00000299164.2:c.1026G>A p.Lys342= p.K342= ENST00000299164 NM_139055.2 342 aaG/aaA 0 +ADAMTS16 UCSF GRCh37 5 5306737 5306737 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 14 50 0 ENST00000274181.7:c.3307C>T p.Leu1103= p.L1103= ENST00000274181 NM_139056.2 1103 Ctg/Ttg 0 +ADAMTSL4 UCSF GRCh37 1 150528791 150528791 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 5 19 0 ENST00000271643.4:c.1525G>A p.Gly509Arg p.G509R ENST00000271643 NM_019032.4 509 Gga/Aga 0 +ADCY8 UCSF GRCh37 8 131848647 131848647 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 9 42 0 ENST00000286355.5:c.2551C>T p.Leu851Phe p.L851F ENST00000286355 NM_001115.2 851 Ctc/Ttc 0 +ADI1 UCSF GRCh37 2 3504731 3504731 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 11 25 0 ENST00000327435.6:c.274G>A p.Asp92Asn p.D92N ENST00000327435 NM_018269.3 92 Gac/Aac 0 +ADNP2 UCSF GRCh37 18 77896524 77896524 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 28 107 0 ENST00000262198.4:c.3228G>A p.Leu1076= p.L1076= ENST00000262198 NM_014913.3 1076 ttG/ttA 0 +ADORA3 UCSF GRCh37 1 112028394 112028394 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 29 84 0 ENST00000369716.4:c.941C>T p.Thr314Ile p.T314I ENST00000369716 NM_020683.6 314 aCc/aTc 0 +AEBP1 UCSF GRCh37 7 44151787 44151787 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 10 29 0 ENST00000223357.3:c.2084G>A p.Gly695Asp p.G695D ENST00000223357 NM_001129.4 695 gGc/gAc 0 +AFAP1 UCSF GRCh37 4 7770645 7770645 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 20 42 0 ENST00000420658.1:c.2344G>A p.Ala782Thr p.A782T ENST00000420658 NM_001134647.1 782 Gcg/Acg 0 +AFAP1 UCSF GRCh37 4 7811454 7811454 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 16 70 0 ENST00000420658.1:c.941G>A p.Gly314Asp p.G314D ENST00000420658 NM_001134647.1 314 gGc/gAc 0 +AFAP1L2 UCSF GRCh37 10 116059077 116059077 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 5 37 0 ENST00000304129.4:c.2055C>T p.His685= p.H685= ENST00000304129 NM_001287824.1 685 caC/caT 0 +AFF3 UCSF GRCh37 2 100627968 100627968 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 79 12 77 0 ENST00000356421.2:c.119G>A p.Arg40Lys p.R40K ENST00000356421 NM_001025108.1 40 aGa/aAa 0 +AGBL1 UCSF GRCh37 15 86697787 86697787 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 8 44 0 ENST00000441037.2:c.251C>T p.Ser84Phe p.S84F ENST00000441037 NM_152336.2 84 tCc/tTc 0 +AGBL2 UCSF GRCh37 11 47684615 47684615 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 110 19 147 1 ENST00000525123.1:c.2498C>T p.Ala833Val p.A833V ENST00000525123 NM_024783.3 833 gCc/gTc 0 +AGER UCSF GRCh37 6 32150123 32150123 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 24 43 0 ENST00000375076.4:c.865C>T p.Pro289Ser p.P289S ENST00000375076 NM_001206929.1 289 Cct/Tct 0 +AGRN UCSF GRCh37 1 979635 979635 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 3 13 0 ENST00000379370.2:c.2146C>T p.Pro716Ser p.P716S ENST00000379370 NM_198576.3 716 Ccg/Tcg 0 +AGT UCSF GRCh37 1 230839975 230839975 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 5 27 0 ENST00000366667.4:c.1233G>A p.Leu411= p.L411= ENST00000366667 NM_000029.3 411 ctG/ctA 0 +AGXT2L1 UCSF GRCh37 4 109681017 109681017 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 9 59 0 ENST00000296486.3:c.223G>A p.Glu75Lys p.E75K ENST00000296486 NM_031279.3 75 Gaa/Aaa 0 +AHNAK UCSF GRCh37 11 62297645 62297645 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 136 70 131 0 ENST00000378024.4:c.4244G>A p.Gly1415Glu p.G1415E ENST00000378024 NM_001620.2 1415 gGa/gAa 0 +AHNAK2 UCSF GRCh37 14 105411656 105411656 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 62 98 0 ENST00000333244.5:c.10132G>A p.Glu3378Lys p.E3378K ENST00000333244 NM_138420.2 3378 Gag/Aag 0 +AHNAK2 UCSF GRCh37 14 105416524 105416524 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 80 102 0 ENST00000333244.5:c.5264C>T p.Ala1755Val p.A1755V ENST00000333244 NM_138420.2 1755 gCc/gTc 0 +AIM1L UCSF GRCh37 1 26673016 26673016 + upstream_gene_variant 5'Flank SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 8 14 0 ENST00000527815 NM_001039775.3 0 +AIPL1 UCSF GRCh37 17 6330210 6330210 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 16 26 0 ENST00000381129.3:c.633G>A p.Leu211= p.L211= ENST00000381129 NM_014336.3 211 ctG/ctA 0 +AK5 UCSF GRCh37 1 78001692 78001692 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 6 48 0 ENST00000354567.2:c.1589C>T p.Ala530Val p.A530V ENST00000354567 NM_174858.2 530 gCc/gTc 0 +AKAP1 UCSF GRCh37 17 55193506 55193506 + synonymous_variant Silent SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 25 19 26 0 ENST00000337714.3:c.2316G>A p.Gly772= p.G772= ENST00000337714 NM_003488.3 772 ggG/ggA 0 +AKAP1 UCSF GRCh37 17 55183547 55183547 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 14 38 0 ENST00000337714.3:c.722G>A p.Gly241Glu p.G241E ENST00000337714 NM_003488.3 241 gGg/gAg 0 +AKAP10 UCSF GRCh37 17 19812583 19812583 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 23 59 0 ENST00000225737.6:c.1894G>A p.Glu632Lys p.E632K ENST00000225737 NM_007202.3 632 Gaa/Aaa 0 +AKAP12 UCSF GRCh37 6 151670458 151670458 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 23 64 0 ENST00000402676.2:c.932C>T p.Thr311Ile p.T311I ENST00000402676 NM_005100.3 311 aCc/aTc 0 +AKAP9 UCSF GRCh37 7 91706181 91706181 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 21 61 0 ENST00000356239.3:c.6625G>A p.Glu2209Lys p.E2209K ENST00000356239 NM_147185.2 2209 Gaa/Aaa 0 +AKNAD1 UCSF GRCh37 1 109394475 109394475 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 87 53 120 0 ENST00000370001.3:c.812C>T p.Pro271Leu p.P271L ENST00000370001 NM_152763.4 271 cCt/cTt 0 +AKR1E2 UCSF GRCh37 10 4872960 4872960 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 32 53 0 ENST00000298375.7:c.133G>A p.Glu45Lys p.E45K ENST00000298375 NM_001040177.2 45 Gag/Aag 0 +ALDH8A1 UCSF GRCh37 6 135260414 135260414 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 30 51 0 ENST00000265605.2:c.582G>A p.Leu194= p.L194= ENST00000265605 NM_022568.3 194 ctG/ctA 0 +ALDOA UCSF GRCh37 16 30080180 30080180 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 24 48 0 ENST00000395248.1:c.583G>A p.Asp195Asn p.D195N ENST00000395248 195 Gac/Aac 0 +ALDOB UCSF GRCh37 9 104192239 104192239 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 22 48 0 ENST00000374855.4:c.122G>A p.Gly41Glu p.G41E ENST00000374855 NM_000035.3 41 gGg/gAg 0 +ALG6 UCSF GRCh37 1 63894432 63894432 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 43 106 0 ENST00000371108.4:c.1087C>T p.Pro363Ser p.P363S ENST00000371108 NM_013339.3 363 Cct/Tct 0 +ALKBH3 UCSF GRCh37 11 43941489 43941489 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 39 75 0 ENST00000302708.4:c.790C>T p.His264Tyr p.H264Y ENST00000302708 NM_139178.3 264 Cac/Tac 0 +ALMS1 UCSF GRCh37 2 73679463 73679463 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 47 87 0 ENST00000264448.6:c.5806C>T p.Pro1936Ser p.P1936S ENST00000264448 NM_015120.4 1936 Cct/Tct 0 +ALMS1 UCSF GRCh37 2 73717043 73717043 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 74 51 121 0 ENST00000264448.6:c.7954C>T p.Pro2652Ser p.P2652S ENST00000264448 NM_015120.4 2652 Cca/Tca 0 +ALMS1 UCSF GRCh37 2 73830377 73830377 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 23 34 0 ENST00000264448.6:c.12305C>T p.Ala4102Val p.A4102V ENST00000264448 NM_015120.4 4102 gCt/gTt 0 +ALPK1 UCSF GRCh37 4 113333097 113333097 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 5 21 0 ENST00000458497.1:c.391G>A p.Ala131Thr p.A131T ENST00000458497 NM_001102406.1 131 Gcc/Acc 0 +ALS2 UCSF GRCh37 2 202606440 202606440 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 6 30 0 ENST00000264276.6:c.2308G>A p.Val770Ile p.V770I ENST00000264276 NM_020919.3 770 Gtc/Atc 0 +AMACR UCSF GRCh37 5 33989386 33989386 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 13 44 0 ENST00000382085.3:c.961C>T p.Gln321Ter p.Q321* ENST00000382085 321 Cag/Tag 0 +AMACR UCSF GRCh37 5 33988422 33988422 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 13 58 0 ENST00000382085.3:c.1176C>T p.Ile392= p.I392= ENST00000382085 392 atC/atT 0 +AMBRA1 UCSF GRCh37 11 46569868 46569868 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 84 54 124 0 ENST00000314845.3:c.63G>A p.Arg21= p.R21= ENST00000314845 NM_017749.3 21 cgG/cgA 0 +AMFR UCSF GRCh37 16 56419852 56419852 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 9 21 0 ENST00000290649.5:c.1359C>T p.Ser453= p.S453= ENST00000290649 NM_001144.5 453 agC/agT 0 +AMMECR1 UCSF GRCh37 X 109507796 109507796 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 13 44 0 ENST00000262844.5:c.505G>A p.Asp169Asn p.D169N ENST00000262844 NM_015365.2 169 Gac/Aac 0 +AMOT UCSF GRCh37 X 112065871 112065871 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 9 29 0 ENST00000371959.3:c.484G>A p.Gly162Arg p.G162R ENST00000371959 NM_001113490.1 162 Gga/Aga 0 +AMY2B UCSF GRCh37 1 104120231 104120231 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 120 69 255 0 ENST00000361355.4:c.1220+1G>A p.X407_splice ENST00000361355 NM_020978.4 0 +AMZ1 UCSF GRCh37 7 2752379 2752379 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 10 9 0 ENST00000312371.4:c.1364C>T p.Pro455Leu p.P455L ENST00000312371 NM_133463.1 455 cCc/cTc 0 +ANK1 UCSF GRCh37 8 41552836 41552836 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 9 26 0 ENST00000265709.8:c.3097G>A p.Glu1033Lys p.E1033K ENST00000265709 NM_001142446.1 1033 Gag/Aag 0 +ANK1 UCSF GRCh37 8 41542129 41542129 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 3 22 0 ENST00000265709.8:c.4593C>T p.Ser1531= p.S1531= ENST00000265709 NM_001142446.1 1531 agC/agT 0 +ANK2 UCSF GRCh37 4 114239724 114239724 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 6 28 0 ENST00000357077.4:c.2848G>A p.Gly950Ser p.G950S ENST00000357077 NM_001148.4 950 Ggc/Agc 0 +ANK2 UCSF GRCh37 4 114275995 114275995 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 111 20 90 0 ENST00000357077.4:c.6221G>A p.Gly2074Glu p.G2074E ENST00000357077 NM_001148.4 2074 gGa/gAa 0 +ANK3 UCSF GRCh37 10 61829559 61829559 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 31 38 0 ENST00000280772.2:c.11080G>A p.Glu3694Lys p.E3694K ENST00000280772 NM_020987.3 3694 Gaa/Aaa 0 +ANK3 UCSF GRCh37 10 61830291 61830291 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 37 69 0 ENST00000280772.2:c.10348G>A p.Gly3450Ser p.G3450S ENST00000280772 NM_020987.3 3450 Ggc/Agc 0 +ANKRD13C UCSF GRCh37 1 70819825 70819825 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 14 24 0 ENST00000370944.4:c.267C>T p.Ser89= p.S89= ENST00000370944 NM_030816.4 89 tcC/tcT 0 +ANKRD18B UCSF GRCh37 9 33548687 33548687 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 86 58 104 0 ENST00000290943.6:c.1715C>T p.Ala572Val p.A572V ENST00000290943 NM_001244752.1 572 gCt/gTt 0 +ANKRD30A UCSF GRCh37 10 37486358 37486358 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 111 19 135 0 ENST00000361713.1:c.2498C>T p.Ser833Phe p.S833F ENST00000361713 NM_052997.2 833 tCt/tTt 0 +ANKRD35 UCSF GRCh37 1 145562121 145562121 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 14 30 0 ENST00000355594.4:c.1809G>A p.Lys603= p.K603= ENST00000355594 NM_144698.4 603 aaG/aaA 0 +ANKRD5 UCSF GRCh37 20 10030860 10030860 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 20 64 0 ENST00000378380.3:c.1643G>A p.Gly548Glu p.G548E ENST00000378380 NM_198798.1 548 gGa/gAa 0 +ANKRD54 UCSF GRCh37 22 38228727 38228727 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 5 22 0 ENST00000215941.4:c.745C>T p.Leu249= p.L249= ENST00000215941 NM_138797.2 249 Ctg/Ttg 0 +ANKS1B UCSF GRCh37 12 99166907 99166907 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 26 113 0 ENST00000547776.2:c.3417C>T p.Asp1139= p.D1139= ENST00000547776 NM_152788.4 1139 gaC/gaT 0 +ANO3 UCSF GRCh37 11 26556003 26556003 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 19 44 0 ENST00000256737.3:c.870C>T p.His290= p.H290= ENST00000256737 NM_031418.2 290 caC/caT 0 +ANO7 UCSF GRCh37 2 242138787 242138787 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 5 18 0 ENST00000274979.8:c.528G>A p.Trp176Ter p.W176* ENST00000274979 NM_001001891.3 176 tgG/tgA 0 +ANTXR2 UCSF GRCh37 4 80905121 80905121 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 80 20 109 0 ENST00000307333.7:c.1090G>A p.Glu364Lys p.E364K ENST00000307333 NM_001145794.1 364 Gaa/Aaa 0 +AP3D1 UCSF GRCh37 19 2129445 2129445 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 5 21 0 ENST00000355272.6:c.604G>A p.Ala202Thr p.A202T ENST00000355272 NM_001261826.1 202 Gct/Act 0 +AP4E1 UCSF GRCh37 15 51250900 51250900 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 135 26 147 0 ENST00000261842.5:c.1760G>A p.Arg587Lys p.R587K ENST00000261842 NM_001252127.1 587 aGa/aAa 0 +APEH UCSF GRCh37 3 49720324 49720324 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 15 26 0 ENST00000296456.5:c.1932C>T p.Asp644= p.D644= ENST00000296456 NM_001640.3 644 gaC/gaT 0 +APIP UCSF GRCh37 11 34916587 34916587 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 91 11 65 0 ENST00000395787.3:c.128G>A p.Gly43Glu p.G43E ENST00000395787 NM_015957.2 43 gGg/gAg 0 +APOBEC3H UCSF GRCh37 22 39497501 39497501 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 7 18 0 ENST00000401756.1:c.410G>A p.Gly137Asp p.G137D ENST00000401756 NM_001166003.1 137 gGc/gAc 0 +APOO UCSF GRCh37 X 23897071 23897071 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 3 21 16 0 ENST00000379226.4:c.198G>A p.Gln66= p.Q66= ENST00000379226 NM_024122.4 66 caG/caA 0 +APPL2 UCSF GRCh37 12 105591584 105591584 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 11 34 0 ENST00000551662.1:c.1029C>T p.Asp343= p.D343= ENST00000551662 343 gaC/gaT 0 +ARAP3 UCSF GRCh37 5 141033770 141033770 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 13 17 0 ENST00000239440.4:c.4382G>A p.Arg1461Lys p.R1461K ENST00000239440 NM_022481.5 1461 aGg/aAg 0 +ARFGAP3 UCSF GRCh37 22 43243638 43243638 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 8 106 0 ENST00000263245.5:c.70G>A p.Val24Met p.V24M ENST00000263245 NM_014570.4 24 Gtg/Atg 0 +ARHGAP21 UCSF GRCh37 10 24874187 24874187 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 89 54 164 0 ENST00000396432.2:c.5031C>T p.Thr1677= p.T1677= ENST00000396432 NM_020824.3 1677 acC/acT 0 +ARHGAP28 UCSF GRCh37 18 6896545 6896545 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 8 57 0 ENST00000419673.2:c.1473C>T p.Leu491= p.L491= ENST00000419673 NM_001010000.2 491 ctC/ctT 0 +ARHGAP30 UCSF GRCh37 1 161024235 161024235 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 19 0 ENST00000368013.3:c.457G>A p.Val153Ile p.V153I ENST00000368013 NM_181720.2 153 Gta/Ata 0 +ARHGAP35 UCSF GRCh37 19 47425094 47425094 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 25 92 0 ENST00000404338.3:c.3162G>A p.Gly1054= p.G1054= ENST00000404338 NM_004491.4 1054 ggG/ggA 0 +ARHGAP42 UCSF GRCh37 11 100847606 100847606 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 35 60 0 ENST00000298815.8:c.2297C>T p.Pro766Leu p.P766L ENST00000298815 NM_152432.2 766 cCc/cTc 0 +ARHGDIA UCSF GRCh37 17 79827721 79827721 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 3 13 0 ENST00000269321.7:c.86C>T p.Pro29Leu p.P29L ENST00000269321 NM_001185078.1 29 cCc/cTc 0 +ARHGEF15 UCSF GRCh37 17 8218574 8218574 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 11 21 0 ENST00000361926.3:c.1239C>T p.Pro413= p.P413= ENST00000361926 NM_173728.3 413 ccC/ccT 0 +ARHGEF2 UCSF GRCh37 1 155931569 155931569 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 18 35 0 ENST00000361247.4:c.1351C>T p.Pro451Ser p.P451S ENST00000361247 NM_001162384.1 451 Cct/Tct 0 +ARHGEF33 UCSF GRCh37 2 39193159 39193159 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 88 41 107 0 ENST00000409978.1:c.2356G>A p.Glu786Lys p.E786K ENST00000409978 786 Gaa/Aaa 0 +ARHGEF40 UCSF GRCh37 14 21543874 21543874 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 9 18 0 ENST00000298694.4:c.1689C>T p.Pro563= p.P563= ENST00000298694 NM_001278529.1 563 ccC/ccT 0 +ARHGEF6 UCSF GRCh37 X 135767925 135767925 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 8 77 0 ENST00000250617.6:c.1303C>T p.Pro435Ser p.P435S ENST00000250617 NM_004840.2 435 Cct/Tct 0 +ARID1A UCSF GRCh37 1 27106143 27106143 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 41 74 0 ENST00000324856.7:c.5754G>A p.Arg1918= p.R1918= ENST00000324856 NM_006015.4 1918 cgG/cgA 0 +ARID4B UCSF GRCh37 1 235386532 235386532 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 42 0 ENST00000264183.3:c.1014G>A p.Leu338= p.L338= ENST00000264183 NM_016374.5 338 ttG/ttA 0 +ARID5B UCSF GRCh37 10 63851799 63851799 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 112 16 113 1 ENST00000279873.7:c.2577G>A p.Arg859= p.R859= ENST00000279873 NM_032199.2 859 agG/agA 0 +ARNT2 UCSF GRCh37 15 80845102 80845102 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 56 107 0 ENST00000303329.4:c.1076G>A p.Gly359Asp p.G359D ENST00000303329 NM_014862.3 359 gGc/gAc 0 +ARSI UCSF GRCh37 5 149677350 149677350 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 4 19 0 ENST00000328668.7:c.1137G>A p.Glu379= p.E379= ENST00000328668 NM_001012301.2 379 gaG/gaA 0 +ART5 UCSF GRCh37 11 3661212 3661212 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 5 22 51 0 ENST00000397068.3:c.447C>T p.Gly149= p.G149= ENST00000397068 NM_053017.3 149 ggC/ggT 0 +ASAP2 UCSF GRCh37 2 9496363 9496363 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 115 17 72 0 ENST00000281419.3:c.1216G>A p.Gly406Arg p.G406R ENST00000281419 NM_003887.2 406 Ggg/Agg 0 +ASAP3 UCSF GRCh37 1 23758293 23758293 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 14 36 0 ENST00000336689.3:c.2442C>T p.Ala814= p.A814= ENST00000336689 NM_017707.3 814 gcC/gcT 0 +ASCC3 UCSF GRCh37 6 101053571 101053571 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 22 67 0 ENST00000369162.2:c.5050C>T p.Leu1684Phe p.L1684F ENST00000369162 NM_006828.2 1684 Ctc/Ttc 0 +ASGR2 UCSF GRCh37 17 7017555 7017555 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 15 35 0 ENST00000380952.2:c.5C>T p.Ala2Val p.A2V ENST00000380952 NM_080912.3 2 gCc/gTc 0 +ASGR2 UCSF GRCh37 17 7010367 7010367 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 7 34 0 ENST00000380952.2:c.615C>T p.Cys205= p.C205= ENST00000380952 NM_080912.3 205 tgC/tgT 0 +ASNA1 UCSF GRCh37 19 12858848 12858849 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P01_Rec Untested WXS Illumina HiSeq 6 0 ENST00000591090.1:c.982dup p.Ala328GlyfsTer90 p.A328Gfs*90 ENST00000591090 326 cgg/cgGg 0 +ASNA1 UCSF GRCh37 19 12858790 12858790 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 9 28 0 ENST00000591090.1:c.919G>A p.Glu307Lys p.E307K ENST00000591090 307 Gag/Aag 0 +ASNS UCSF GRCh37 7 97488694 97488694 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 25 66 0 ENST00000175506.4:c.504G>A p.Lys168= p.K168= ENST00000175506 NM_183356.3 168 aaG/aaA 0 +ASPM UCSF GRCh37 1 197102528 197102528 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 30 60 0 ENST00000367409.4:c.2371G>A p.Ala791Thr p.A791T ENST00000367409 NM_018136.4 791 Gct/Act 0 +ASPM UCSF GRCh37 1 197104229 197104229 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 13 50 0 ENST00000367409.4:c.2170G>A p.Glu724Lys p.E724K ENST00000367409 NM_018136.4 724 Gaa/Aaa 0 +ASTL UCSF GRCh37 2 96795688 96795688 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 6 24 0 ENST00000342380.2:c.749C>T p.Thr250Ile p.T250I ENST00000342380 NM_001002036.3 250 aCc/aTc 0 +ASTN2 UCSF GRCh37 9 119203066 119203066 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 35 70 0 ENST00000361209.2:c.3451G>A p.Ala1151Thr p.A1151T ENST00000361209 NM_014010.4 1151 Gct/Act 0 +ATE1 UCSF GRCh37 10 123600639 123600639 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 19 44 0 ENST00000369043.3:c.1115C>T p.Pro372Leu p.P372L ENST00000369043 NM_007041.2 372 cCt/cTt 0 +ATF6B UCSF GRCh37 6 32085767 32085767 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 14 25 0 ENST00000375203.3:c.1293G>A p.Gly431= p.G431= ENST00000375203 NM_001136153.1 431 ggG/ggA 0 +ATG13 UCSF GRCh37 11 46671758 46671758 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 42 75 0 ENST00000528494.1:c.349G>A p.Val117Met p.V117M ENST00000528494 NM_001205119.1 117 Gtg/Atg 0 +ATM UCSF GRCh37 11 108165786 108165786 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 77 48 143 0 ENST00000278616.4:c.4909G>A p.Asp1637Asn p.D1637N ENST00000278616 NM_000051.3 1637 Gat/Aat 0 +ATN1 UCSF GRCh37 12 7046299 7046299 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 12 38 0 ENST00000356654.4:c.1869C>T p.Ser623= p.S623= ENST00000356654 NM_001007026.1 623 tcC/tcT 0 +ATP10D UCSF GRCh37 4 47583992 47583992 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 39 83 0 ENST00000273859.3:c.3664G>A p.Asp1222Asn p.D1222N ENST00000273859 NM_020453.3 1222 Gat/Aat 0 +ATP10D UCSF GRCh37 4 47514620 47514620 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 62 0 ENST00000273859.3:c.63G>A p.Arg21= p.R21= ENST00000273859 NM_020453.3 21 agG/agA 0 +ATP1A4 UCSF GRCh37 1 160136342 160136342 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 6 46 0 ENST00000368081.4:c.1072C>T p.Arg358Cys p.R358C ENST00000368081 NM_144699.3 358 Cgc/Tgc 0 +ATP5J2-PTCD1 UCSF GRCh37 7 99017752 99017752 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 35 58 0 ENST00000413834.1:c.2088C>T p.Tyr696= p.Y696= ENST00000413834 696 taC/taT 0 +ATP6AP1L UCSF GRCh37 5 81608429 81608429 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 38 125 0 ENST00000380167.4:c.132-1G>A p.X44_splice ENST00000380167 0 +ATP6V0A1 UCSF GRCh37 17 40652850 40652850 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 63 103 0 ENST00000264649.6:c.1826C>T p.Ser609Phe p.S609F ENST00000264649 NM_001130020.1 609 tCt/tTt 0 +ATP8B4 UCSF GRCh37 15 50168672 50168672 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 29 58 0 ENST00000284509.6:c.2830G>A p.Gly944Arg p.G944R ENST00000284509 NM_024837.3 944 Gga/Aga 0 +ATP9B UCSF GRCh37 18 77133916 77133916 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 11 28 0 ENST00000426216.2:c.3089G>A p.Gly1030Glu p.G1030E ENST00000426216 NM_198531.3 1030 gGg/gAg 0 +ATRX UCSF GRCh37 X 76938230 76938231 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Rec Untested WXS Illumina HiSeq 92 0 ENST00000373344.5:c.2518dup p.Arg840LysfsTer9 p.R840Kfs*9 ENST00000373344 NM_000489.3 839 -/A 0 +ATXN2L UCSF GRCh37 16 28841357 28841357 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 4 11 0 ENST00000395547.2:c.1012G>A p.Glu338Lys p.E338K ENST00000395547 NM_148414.2 338 Gag/Aag 0 +ATXN7L1 UCSF GRCh37 7 105279975 105279975 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 29 79 0 ENST00000419735.3:c.904C>T p.Pro302Ser p.P302S ENST00000419735 NM_020725.1 302 Ccc/Tcc 0 +AUTS2 UCSF GRCh37 7 70228160 70228160 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 11 11 0 ENST00000342771.4:c.1047G>A p.Gln349= p.Q349= ENST00000342771 NM_015570.2 349 caG/caA 0 +AVPR2 UCSF GRCh37 X 153171289 153171289 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 2 17 11 0 ENST00000358927.2:c.329C>T p.Ala110Val p.A110V ENST00000358927 110 gCc/gTc 0 +AXDND1 UCSF GRCh37 1 179364322 179364322 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 127 154 0 ENST00000367618.3:c.1094C>T p.Ala365Val p.A365V ENST00000367618 NM_144696.5 365 gCg/gTg 0 +B4GALNT4 UCSF GRCh37 11 373242 373242 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 5 34 0 ENST00000329962.6:c.587G>A p.Ser196Asn p.S196N ENST00000329962 NM_178537.4 196 aGt/aAt 0 +B7H6 UCSF GRCh37 11 17378221 17378221 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 16 33 0 ENST00000338965.4:c.94G>A p.Ala32Thr p.A32T ENST00000338965 NM_001202439.1 32 Gca/Aca 0 +BATF UCSF GRCh37 14 76012859 76012859 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 13 0 ENST00000286639.6:c.223C>T p.Leu75Phe p.L75F ENST00000286639 NM_006399.3 75 Ctc/Ttc 0 +BAZ1A UCSF GRCh37 14 35262103 35262103 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 82 16 76 0 ENST00000360310.1:c.1388G>A p.Gly463Glu p.G463E ENST00000360310 NM_013448.2 463 gGa/gAa 0 +BBS10 UCSF GRCh37 12 76740484 76740484 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 23 98 0 ENST00000393262.3:c.1281C>T p.Asp427= p.D427= ENST00000393262 NM_024685.3 427 gaC/gaT 0 +BBX UCSF GRCh37 3 107435664 107435664 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 35 68 0 ENST00000325805.8:c.373G>A p.Glu125Lys p.E125K ENST00000325805 125 Gaa/Aaa 0 +BCAS1 UCSF GRCh37 20 52644934 52644934 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 79 58 89 0 ENST00000395961.3:c.720G>A p.Gly240= p.G240= ENST00000395961 NM_003657.2 240 ggG/ggA 0 +BCLAF1 UCSF GRCh37 6 136599392 136599392 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 213 46 206 0 ENST00000531224.1:c.627C>T p.Ser209= p.S209= ENST00000531224 NM_001077441.1 209 tcC/tcT 0 +BCO2 UCSF GRCh37 11 112050076 112050076 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 91 16 136 0 ENST00000357685.5:c.164C>T p.Ala55Val p.A55V ENST00000357685 55 gCa/gTa 0 +BCO2 UCSF GRCh37 11 112064368 112064368 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0021 P01_Rec Untested WXS Illumina HiSeq 43 7 61 0 ENST00000357685.5:c.465G>A p.Lys155= p.K155= ENST00000357685 155 aaG/aaA 0 +BCOR UCSF GRCh37 X 39931725 39931725 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 6 14 0 ENST00000378444.4:c.2874G>A p.Lys958= p.K958= ENST00000378444 NM_001123385.1 958 aaG/aaA 0 +BDP1 UCSF GRCh37 5 70763227 70763227 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 108 53 185 0 ENST00000358731.4:c.832G>A p.Glu278Lys p.E278K ENST00000358731 NM_018429.2 278 Gaa/Aaa 0 +BDP1 UCSF GRCh37 5 70811923 70811923 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 26 25 45 0 ENST00000358731.4:c.4685A>G p.Lys1562Arg p.K1562R ENST00000358731 NM_018429.2 1562 aAg/aGg 0 +BDP1 UCSF GRCh37 5 70806948 70806948 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 28 150 0 ENST00000358731.4:c.4029C>T p.Asp1343= p.D1343= ENST00000358731 NM_018429.2 1343 gaC/gaT 0 +BEND2 UCSF GRCh37 X 18183254 18183254 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 66 11 49 0 ENST00000380033.4:c.2275C>T p.Arg759Cys p.R759C ENST00000380033 NM_153346.4 759 Cgt/Tgt 0 +BIRC2 UCSF GRCh37 11 102234398 102234398 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 14 48 0 ENST00000227758.2:c.1075-1G>A p.X359_splice ENST00000227758 NM_001166.4 0 +BIVM UCSF GRCh37 13 103492195 103492195 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 47 103 0 ENST00000257336.1:c.1492G>A p.Asp498Asn p.D498N ENST00000257336 NM_017693.3 498 Gat/Aat 0 +BMPER UCSF GRCh37 7 34125416 34125416 + missense_variant Missense_Mutation SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 24 9 33 0 ENST00000297161.2:c.1457C>G p.Ala486Gly p.A486G ENST00000297161 NM_133468.4 486 gCg/gGg 0 +BMS1 UCSF GRCh37 10 43294010 43294010 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 38 64 0 ENST00000374518.5:c.2184G>A p.Lys728= p.K728= ENST00000374518 NM_014753.3 728 aaG/aaA 0 +BOLL UCSF GRCh37 2 198631273 198631273 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 33 16 47 0 ENST00000321801.7:c.571C>T p.Pro191Ser p.P191S ENST00000321801 NM_197970.2 191 Cct/Tct 0 +BPGM UCSF GRCh37 7 134346330 134346330 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 32 68 0 ENST00000393132.2:c.71G>A p.Ser24Asn p.S24N ENST00000393132 NM_199186.2 24 aGc/aAc 0 +BPGM UCSF GRCh37 7 134346538 134346538 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 16 36 0 ENST00000393132.2:c.279G>A p.Gly93= p.G93= ENST00000393132 NM_199186.2 93 ggG/ggA 0 +BPIFA1 UCSF GRCh37 20 31829272 31829272 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 58 48 66 0 ENST00000354297.4:c.663C>T p.Gly221= p.G221= ENST00000354297 NM_130852.2 221 ggC/ggT 0 +BPIFB2 UCSF GRCh37 20 31606597 31606597 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 19 29 0 ENST00000170150.3:c.824G>A p.Gly275Asp p.G275D ENST00000170150 NM_025227.2 275 gGt/gAt 0 +BRE UCSF GRCh37 2 28464226 28464226 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 16 58 0 ENST00000344773.2:c.817G>A p.Glu273Lys p.E273K ENST00000344773 NM_004899.4 273 Gag/Aag 0 +BRIP1 UCSF GRCh37 17 59878736 59878736 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 128 59 172 0 ENST00000259008.2:c.1018C>T p.Leu340Phe p.L340F ENST00000259008 NM_032043.2 340 Ctt/Ttt 0 +BRIX1 UCSF GRCh37 5 34925341 34925341 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 16 12 31 0 ENST00000336767.5:c.803T>C p.Val268Ala p.V268A ENST00000336767 NM_018321.3 268 gTc/gCc 0 +BSCL2 UCSF GRCh37 11 62457979 62457979 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 8 35 0 ENST00000433053.1:c.1249G>A p.Glu417Lys p.E417K ENST00000433053 417 Gaa/Aaa 0 +BTN2A1 UCSF GRCh37 6 26459959 26459959 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 23 53 0 ENST00000312541.5:c.333C>T p.Val111= p.V111= ENST00000312541 NM_007049.4 111 gtC/gtT 0 +BTNL8 UCSF GRCh37 5 180376987 180376987 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 33 26 0 ENST00000340184.4:c.946C>T p.Gln316Ter p.Q316* ENST00000340184 NM_001040462.2 316 Cag/Tag 0 +BZRAP1 UCSF GRCh37 17 56384227 56384227 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 9 48 0 ENST00000343736.4:c.5086C>T p.Pro1696Ser p.P1696S ENST00000343736 1696 Cct/Tct 0 +BZRAP1 UCSF GRCh37 17 56395646 56395646 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 6 27 0 ENST00000343736.4:c.1867C>T p.Pro623Ser p.P623S ENST00000343736 623 Cct/Tct 0 +C10orf12 UCSF GRCh37 10 98744633 98744633 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 32 112 0 ENST00000286067.2:c.3486G>A p.Arg1162= p.R1162= ENST00000286067 NM_015652.2 1162 agG/agA 0 +C10orf120 UCSF GRCh37 10 124457495 124457496 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Rec Untested WXS Illumina HiSeq 8 0 ENST00000329446.4:c.762dup p.Cys255MetfsTer8 p.C255Mfs*8 ENST00000329446 NM_001010912.2 254 aaa/aaAa 0 +C10orf2 UCSF GRCh37 10 102748828 102748828 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 110 20 76 0 ENST00000311916.2:c.861G>A p.Thr287= p.T287= ENST00000311916 NM_021830.4 287 acG/acA 0 +C10orf28 UCSF GRCh37 10 99968816 99968816 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 64 110 0 ENST00000298999.3:c.945C>T p.Ile315= p.I315= ENST00000298999 NM_014472.4 315 atC/atT 0 +C10orf92 UCSF GRCh37 10 134628221 134628221 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 2 14 20 0 ENST00000368586.5:c.7218C>T p.Asp2406= p.D2406= ENST00000368586 NM_001200049.2 2406 gaC/gaT 0 +C11orf41 UCSF GRCh37 11 33604909 33604909 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 8 32 0 ENST00000321505.4:c.3537C>T p.Asn1179= p.N1179= ENST00000321505 1179 aaC/aaT 0 +C11orf80 UCSF GRCh37 11 66571660 66571660 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 25 96 0 ENST00000360962.4:c.1037C>T p.Ser346Phe p.S346F ENST00000360962 NM_024650.3 346 tCc/tTc 0 +C14orf159 UCSF GRCh37 14 91681764 91681764 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 15 52 0 ENST00000518868.1:c.1580G>A p.Gly527Glu p.G527E ENST00000518868 NM_001286470.1 527 gGa/gAa 0 +C14orf159 UCSF GRCh37 14 91681784 91681784 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0069,snp132_rs115874122 P01_Rec Untested WXS Illumina HiSeq 25 15 51 0 ENST00000518868.1:c.1600G>A p.Ala534Thr p.A534T ENST00000518868 NM_001286470.1 534 Gca/Aca 0 +C14orf183 UCSF GRCh37 14 50558224 50558224 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 4 22 0 ENST00000305273.1:c.344C>T p.Ser115Phe p.S115F ENST00000305273 NM_001014830.1 115 tCc/tTc 0 +C15orf55 UCSF GRCh37 15 34640190 34640190 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 29 44 0 ENST00000333756.4:c.37G>A p.Asp13Asn p.D13N ENST00000333756 NM_175741.1 13 Gat/Aat 0 +C17orf57 UCSF GRCh37 17 45479557 45479557 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 13 65 0 ENST00000331493.2:c.2005G>A p.Ala669Thr p.A669T ENST00000331493 NM_152347.4 669 Gcc/Acc 0 +C17orf90 UCSF GRCh37 17 79632460 79632460 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 8 19 0 ENST00000374741.3:c.215G>A p.Gly72Asp p.G72D ENST00000374741 NM_001039842.1 72 gGc/gAc 0 +C18orf1 UCSF GRCh37 18 13645276 13645276 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 27 55 0 ENST00000361205.4:c.541C>T p.Pro181Ser p.P181S ENST00000361205 181 Cct/Tct 0 +C18orf34 UCSF GRCh37 18 30913143 30913143 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P01_Rec Untested WXS Illumina HiSeq 6 0 ENST00000383096.3:c.874delA p.Met292TrpfsTer3 p.M292Wfs*3 ENST00000383096 292 Atg/tg 0 +C18orf34 UCSF GRCh37 18 30803094 30803094 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 44 148 0 ENST00000383096.3:c.1908C>T p.Thr636= p.T636= ENST00000383096 636 acC/acT 0 +C18orf55 UCSF GRCh37 18 71816298 71816298 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 59 31 76 0 ENST00000169551.6:c.255G>A p.Val85= p.V85= ENST00000169551 NM_014177.2 85 gtG/gtA 0 +C1GALT1 UCSF GRCh37 7 7278542 7278542 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 15 53 0 ENST00000436587.2:c.877C>T p.Pro293Ser p.P293S ENST00000436587 NM_020156.4 293 Cct/Tct 0 +C1orf112 UCSF GRCh37 1 169773349 169773349 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 112 26 121 0 ENST00000286031.6:c.446A>G p.Asp149Gly p.D149G ENST00000286031 NM_018186.2 149 gAt/gGt 0 +C1orf116 UCSF GRCh37 1 207196449 207196449 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 13 42 0 ENST00000359470.5:c.660G>A p.Gly220= p.G220= ENST00000359470 NM_023938.5 220 ggG/ggA 0 +C1orf87 UCSF GRCh37 1 60505800 60505800 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.00092 P01_Rec Untested WXS Illumina HiSeq 76 34 81 0 ENST00000371201.3:c.536C>T p.Ala179Val p.A179V ENST00000371201 NM_152377.2 179 gCc/gTc 0 +C1orf95 UCSF GRCh37 1 226784582 226784582 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 28 45 0 ENST00000366788.3:c.282G>A p.Trp94Ter p.W94* ENST00000366788 NM_001003665.3 94 tgG/tgA 0 +C1QTNF2 UCSF GRCh37 5 159776608 159776608 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 4 38 0 ENST00000393975.3:c.560G>A p.Ser187Asn p.S187N ENST00000393975 NM_031908.4 187 aGc/aAc 0 +C1S UCSF GRCh37 12 7172489 7172489 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 16 84 0 ENST00000406697.1:c.603G>A p.Arg201= p.R201= ENST00000406697 201 agG/agA 0 +C20orf12 UCSF GRCh37 20 18395058 18395058 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 27 55 0 ENST00000262547.5:c.1176C>T p.Ser392= p.S392= ENST00000262547 NM_001099407.1 392 tcC/tcT 0 +C20orf12 UCSF GRCh37 20 18371103 18371103 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 14 67 0 ENST00000262547.5:c.1810C>T p.Pro604Ser p.P604S ENST00000262547 NM_001099407.1 604 Cct/Tct 0 +C20orf194 UCSF GRCh37 20 3251135 3251135 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 23 43 0 ENST00000252032.9:c.2724C>T p.Ser908= p.S908= ENST00000252032 NM_001009984.2 908 agC/agT 0 +C21orf7 UCSF GRCh37 21 30464779 30464779 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 40 73 0 ENST00000399947.2:c.247G>A p.Ala83Thr p.A83T ENST00000399947 NM_020152.2 83 Gca/Aca 0 +C22orf29 UCSF GRCh37 22 19839596 19839596 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 13 23 0 ENST00000405640.1:c.189G>A p.Glu63= p.E63= ENST00000405640 63 gaG/gaA 0 +C2CD3 UCSF GRCh37 11 73825484 73825484 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 17 21 0 ENST00000313663.7:c.1675C>T p.Pro559Ser p.P559S ENST00000313663 NM_015531.4 559 Cct/Tct 0 +C3orf20 UCSF GRCh37 3 14724457 14724457 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 17 33 0 ENST00000253697.3:c.237G>A p.Val79= p.V79= ENST00000253697 NM_032137.4 79 gtG/gtA 0 +C3orf39 UCSF GRCh37 3 43121858 43121858 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 8 24 0 ENST00000344697.2:c.1066C>T p.Pro356Ser p.P356S ENST00000344697 NM_032806.5 356 Ccc/Tcc 0 +C3orf54 UCSF GRCh37 3 49842058 49842058 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 3 21 0 ENST00000333323.4:c.502G>A p.Glu168Lys p.E168K ENST00000333323 NM_203370.1 168 Gaa/Aaa 0 +C3orf55 UCSF GRCh37 3 157289050 157289050 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 15 27 0 ENST00000449199.2:c.168G>A p.Leu56= p.L56= ENST00000449199 NM_001130002.2 56 ctG/ctA 0 +C3orf77 UCSF GRCh37 3 44285883 44285883 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P01_Rec Untested WXS Illumina HiSeq 17 0 ENST00000309765.4:c.1893del p.Ala632LeufsTer5 p.A632Lfs*5 ENST00000309765 NM_001145030.1 629 Aaa/aa 0 +C3orf77 UCSF GRCh37 3 44285367 44285367 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 23 116 0 ENST00000309765.4:c.1369C>T p.Pro457Ser p.P457S ENST00000309765 NM_001145030.1 457 Cct/Tct 0 +C3orf77 UCSF GRCh37 3 44286639 44286639 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 39 85 0 ENST00000309765.4:c.2641G>A p.Glu881Lys p.E881K ENST00000309765 NM_001145030.1 881 Gag/Aag 0 +C4orf19 UCSF GRCh37 4 37592527 37592527 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 24 44 0 ENST00000284437.6:c.850G>A p.Asp284Asn p.D284N ENST00000284437 NM_018302.2 284 Gat/Aat 0 +C4orf6 UCSF GRCh37 4 5527144 5527144 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 26 38 0 ENST00000195455.2:c.87G>A p.Gly29= p.G29= ENST00000195455 NM_005750.2 29 ggG/ggA 0 +C5 UCSF GRCh37 9 123734242 123734242 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 16 43 0 ENST00000223642.1:c.4046G>A p.Ser1349Asn p.S1349N ENST00000223642 NM_001735.2 1349 aGt/aAt 0 +C5 UCSF GRCh37 9 123783936 123783936 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 112 48 83 0 ENST00000223642.1:c.1153G>A p.Gly385Arg p.G385R ENST00000223642 NM_001735.2 385 Gga/Aga 0 +C5orf42 UCSF GRCh37 5 37125417 37125417 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 118 32 142 0 ENST00000425232.2:c.8725G>A p.Ala2909Thr p.A2909T ENST00000425232 NM_023073.3 2909 Gca/Aca 0 +C5orf43 UCSF GRCh37 5 60455983 60455983 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 16 73 0 ENST00000339020.3:c.16G>A p.Ala6Thr p.A6T ENST00000339020 NM_001048249.3 6 Gct/Act 0 +C6orf204 UCSF GRCh37 6 118832578 118832578 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 26 76 1 ENST00000368488.5:c.1149G>A p.Arg383= p.R383= ENST00000368488 NM_001178035.1 383 cgG/cgA 0 +C6orf58 UCSF GRCh37 6 127899845 127899845 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 83 46 101 0 ENST00000329722.7:c.316C>T p.Pro106Ser p.P106S ENST00000329722 NM_001010905.2 106 Cca/Tca 0 +C7 UCSF GRCh37 5 40958327 40958327 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 29 68 0 ENST00000313164.9:c.1453G>A p.Ala485Thr p.A485T ENST00000313164 NM_000587.2 485 Gcg/Acg 0 +C7 UCSF GRCh37 5 40979915 40979915 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 73 18 69 0 ENST00000313164.9:c.2254G>A p.Gly752Ser p.G752S ENST00000313164 NM_000587.2 752 Ggt/Agt 0 +C7orf42 UCSF GRCh37 7 66416123 66416123 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 29 29 0 ENST00000341567.4:c.780+1G>A p.X260_splice ENST00000341567 NM_017994.4 0 +C7orf61 UCSF GRCh37 7 100061155 100061155 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 20 39 0 ENST00000332375.3:c.218C>T p.Ser73Phe p.S73F ENST00000332375 NM_001004323.1 73 tCc/tTc 0 +C8B UCSF GRCh37 1 57395081 57395081 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 20 46 0 ENST00000371237.4:c.1772C>T p.Ser591Phe p.S591F ENST00000371237 NM_000066.3 591 tCc/tTc 0 +C9orf102 UCSF GRCh37 9 98678678 98678678 + missense_variant Missense_Mutation SNP A A T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 28 71 0 ENST00000288985.7:c.1153A>T p.Thr385Ser p.T385S ENST00000288985 NM_001010895.2 385 Act/Tct 0 +C9orf135 UCSF GRCh37 9 72435886 72435886 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 21 10 16 0 ENST00000377197.3:c.91G>A p.Gly31Ser p.G31S ENST00000377197 NM_001010940.1 31 Ggc/Agc 0 +C9orf79 UCSF GRCh37 9 90500676 90500676 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 33 62 0 ENST00000325643.5:c.1274C>T p.Ala425Val p.A425V ENST00000325643 NM_178828.4 425 gCc/gTc 0 +CA13 UCSF GRCh37 8 86171690 86171690 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 6 76 0 ENST00000321764.3:c.276G>A p.Arg92= p.R92= ENST00000321764 NM_198584.2 92 cgG/cgA 0 +CABIN1 UCSF GRCh37 22 24468334 24468334 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 10 15 0 ENST00000398319.2:c.2506G>A p.Glu836Lys p.E836K ENST00000398319 NM_001199281.1 836 Gag/Aag 0 +CABYR UCSF GRCh37 18 21739906 21739906 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 72 135 0 ENST00000399496.3:c.1012G>A p.Val338Ile p.V338I ENST00000399496 NM_012189.3 338 Gta/Ata 0 +CACNA1B UCSF GRCh37 9 140811728 140811728 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 96 23 43 0 ENST00000371372.1:c.811G>A p.Glu271Lys p.E271K ENST00000371372 NM_001243812.1 271 Gag/Aag 0 +CACNA1H UCSF GRCh37 16 1262081 1262081 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 19 31 0 ENST00000348261.5:c.4702G>A p.Glu1568Lys p.E1568K ENST00000348261 NM_021098.2 1568 Gag/Aag 0 +CACNA2D1 UCSF GRCh37 7 81636994 81636994 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 5 30 0 ENST00000356860.3:c.1440+1G>A p.X480_splice ENST00000356860 NM_000722.2 0 +CACNA2D3 UCSF GRCh37 3 54871232 54871232 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 120 39 92 0 ENST00000474759.1:c.1445C>T p.Pro482Leu p.P482L ENST00000474759 NM_018398.2 482 cCt/cTt 0 +CACNA2D3 UCSF GRCh37 3 54786625 54786625 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 73 24 39 0 ENST00000474759.1:c.1168-1G>A p.X390_splice ENST00000474759 NM_018398.2 0 +CACNA2D3 UCSF GRCh37 3 55108230 55108230 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 29 58 0 ENST00000474759.1:c.3273G>A p.Arg1091= p.R1091= ENST00000474759 NM_018398.2 1091 agG/agA 0 +CACNB4 UCSF GRCh37 2 152830192 152830192 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 66 18 66 0 ENST00000539935.1:c.148-90308C>T *50* ENST00000539935 NM_001145798.1 0 +CAD UCSF GRCh37 2 27454858 27454858 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 21 49 0 ENST00000264705.4:c.2411C>T p.Thr804Ile p.T804I ENST00000264705 NM_004341.3 804 aCt/aTt 0 +CALML4 UCSF GRCh37 15 68497602 68497602 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 4 36 0 ENST00000467889.1:c.113G>A p.Ser38Asn p.S38N ENST00000467889 NM_033429.2 38 aGc/aAc 0 +CAMK2D UCSF GRCh37 4 114458538 114458538 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 29 87 0 ENST00000342666.5:c.476G>A p.Gly159Asp p.G159D ENST00000342666 159 gGc/gAc 0 +CAMSAP3 UCSF GRCh37 19 7673051 7673051 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 4 10 0 ENST00000446248.2:c.742C>T p.Pro248Ser p.P248S ENST00000446248 NM_001080429.2 248 Ccc/Tcc 0 +CAPN9 UCSF GRCh37 1 230883271 230883271 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 23 25 0 ENST00000271971.2:c.29C>T p.Pro10Leu p.P10L ENST00000271971 NM_006615.2 10 cCt/cTt 0 +CAPS2 UCSF GRCh37 12 75715268 75715268 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 44 133 0 ENST00000409445.3:c.437G>A p.Gly146Asp p.G146D ENST00000409445 NM_032606.3 146 gGc/gAc 0 +CARM1 UCSF GRCh37 19 11018797 11018797 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 5 26 0 ENST00000327064.4:c.429G>A p.Glu143= p.E143= ENST00000327064 NM_199141.1 143 gaG/gaA 0 +CASC1 UCSF GRCh37 12 25308335 25308335 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 18 49 0 ENST00000395987.3:c.210G>A p.Arg70= p.R70= ENST00000395987 NM_018272.3 70 agG/agA 0 +CASKIN2 UCSF GRCh37 17 73499335 73499335 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 8 16 0 ENST00000321617.3:c.1820G>A p.Gly607Glu p.G607E ENST00000321617 NM_020753.4 607 gGg/gAg 0 +CASP7 UCSF GRCh37 10 115489265 115489265 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 18 34 0 ENST00000369321.2:c.977C>T p.Ser326Phe p.S326F ENST00000369321 NM_033338.5 326 tCc/tTc 0 +CASP8 UCSF GRCh37 2 202134309 202134309 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 35 0 ENST00000358485.4:c.483-1930G>A *161* ENST00000358485 NM_001080125.1 0 +CASP8AP2 UCSF GRCh37 6 90573777 90573777 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 63 182 0 ENST00000551025.1:n.3786C>T *1262* ENST00000551025 0 +CASP8AP2 UCSF GRCh37 6 90575760 90575760 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 4 32 65 0 ENST00000551025.1:n.4188C>T *1396* ENST00000551025 0 +CASZ1 UCSF GRCh37 1 10713516 10713516 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 6 12 0 ENST00000377022.3:c.2598C>T p.Ile866= p.I866= ENST00000377022 NM_001079843.2 866 atC/atT 0 +CATSPER2 UCSF GRCh37 15 43931847 43931847 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 11 105 0 ENST00000321596.5:c.711C>T p.Ala237= p.A237= ENST00000321596 237 gcC/gcT 0 +CBL UCSF GRCh37 11 119167732 119167732 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 30 42 0 ENST00000264033.4:c.2141C>T p.Ser714Phe p.S714F ENST00000264033 NM_005188.3 714 tCc/tTc 0 +CBLL1 UCSF GRCh37 7 107389382 107389382 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 131 23 91 0 ENST00000440859.3:c.71G>A p.Arg24Lys p.R24K ENST00000440859 NM_024814.2 24 aGa/aAa 0 +CBS UCSF GRCh37 21 44483181 44483181 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 14 17 0 ENST00000398165.3:c.836G>A p.Gly279Glu p.G279E ENST00000398165 NM_000071.2 279 gGg/gAg 0 +CBX1 UCSF GRCh37 17 46154300 46154300 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 48 79 0 ENST00000393408.3:c.67G>A p.Val23Met p.V23M ENST00000393408 NM_006807.4 23 Gtg/Atg 0 +CBX1 UCSF GRCh37 17 46153494 46153494 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 25 39 0 ENST00000393408.3:c.187C>T p.Leu63Phe p.L63F ENST00000393408 NM_006807.4 63 Ctc/Ttc 0 +CC2D1A UCSF GRCh37 19 14038004 14038004 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 8 21 0 ENST00000318003.7:c.2242G>A p.Asp748Asn p.D748N ENST00000318003 NM_017721.4 748 Gac/Aac 0 +CC2D1A UCSF GRCh37 19 14037861 14037861 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 12 24 0 ENST00000318003.7:c.2196G>A p.Lys732= p.K732= ENST00000318003 NM_017721.4 732 aaG/aaA 0 +CC2D2A UCSF GRCh37 4 15565134 15565134 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 7 41 0 ENST00000424120.1:c.3171G>A p.Lys1057= p.K1057= ENST00000424120 1057 aaG/aaA 0 +CCDC108 UCSF GRCh37 2 219896288 219896288 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 25 54 0 ENST00000341552.5:c.738C>T p.Cys246= p.C246= ENST00000341552 NM_194302.3 246 tgC/tgT 0 +CCDC116 UCSF GRCh37 22 21990936 21990936 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 24 31 0 ENST00000292779.3:c.1419G>A p.Arg473= p.R473= ENST00000292779 NM_152612.2 473 agG/agA 0 +CCDC135 UCSF GRCh37 16 57734080 57734080 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 41 56 0 ENST00000360716.3:c.402G>A p.Arg134= p.R134= ENST00000360716 134 cgG/cgA 0 +CCDC165 UCSF GRCh37 18 8825043 8825043 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 5 11 0 ENST00000359865.3:c.3535C>T p.Leu1179= p.L1179= ENST00000359865 NM_015210.3 1179 Ctg/Ttg 0 +CCDC17 UCSF GRCh37 1 46087995 46087995 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 5 32 0 ENST00000528266.1:c.885G>A p.Glu295= p.E295= ENST00000528266 295 gaG/gaA 0 +CCDC82 UCSF GRCh37 11 96117446 96117446 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 150 30 134 0 ENST00000278520.5:c.466G>A p.Glu156Lys p.E156K ENST00000278520 156 Gag/Aag 0 +CCDC93 UCSF GRCh37 2 118766140 118766140 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 47 147 0 ENST00000376300.2:c.137G>A p.Gly46Asp p.G46D ENST00000376300 NM_019044.4 46 gGc/gAc 0 +CCHCR1 UCSF GRCh37 6 31118537 31118537 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 127 50 74 0 ENST00000396268.3:c.1066G>A p.Glu356Lys p.E356K ENST00000396268 NM_001105563.1 356 Gaa/Aaa 0 +CCNA1 UCSF GRCh37 13 37014243 37014243 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 25 124 0 ENST00000255465.4:c.1021G>A p.Val341Ile p.V341I ENST00000255465 341 Gta/Ata 0 +CCNH UCSF GRCh37 5 86700720 86700720 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 34 95 0 ENST00000256897.4:c.630C>T p.Ser210= p.S210= ENST00000256897 NM_001239.3 210 tcC/tcT 0 +CCP110 UCSF GRCh37 16 19548215 19548215 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 40 128 0 ENST00000381396.5:c.1224G>A p.Met408Ile p.M408I ENST00000381396 NM_001199022.1 408 atG/atA 0 +CD163 UCSF GRCh37 12 7637880 7637880 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 14 77 0 ENST00000359156.4:c.2591G>A p.Cys864Tyr p.C864Y ENST00000359156 NM_004244.5 864 tGc/tAc 0 +CD180 UCSF GRCh37 5 66478865 66478865 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 11 90 0 ENST00000256447.4:c.1806G>A p.Ser602= p.S602= ENST00000256447 NM_005582.2 602 tcG/tcA 0 +CD1D UCSF GRCh37 1 158151967 158151967 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 152 19 164 0 ENST00000368171.3:c.474G>A p.Trp158Ter p.W158* ENST00000368171 NM_001766.3 158 tgG/tgA 0 +CD209 UCSF GRCh37 19 7810855 7810855 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 91 58 74 0 ENST00000315599.7:c.297G>A p.Glu99= p.E99= ENST00000315599 NM_021155.3 99 gaG/gaA 0 +CD82 UCSF GRCh37 11 44640606 44640606 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 14 15 0 ENST00000227155.4:c.734G>A p.Gly245Glu p.G245E ENST00000227155 NM_002231.3 245 gGg/gAg 0 +CDAN1 UCSF GRCh37 15 43020446 43020446 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 15 24 0 ENST00000356231.3:c.2824C>T p.Pro942Ser p.P942S ENST00000356231 NM_138477.2 942 Cct/Tct 0 +CDCP2 UCSF GRCh37 1 54605765 54605765 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 8 14 0 ENST00000371330.1:c.778G>A p.Val260Ile p.V260I ENST00000371330 NM_201546.3 260 Gta/Ata 0 +CDH10 UCSF GRCh37 5 24537507 24537507 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 134 21 165 0 ENST00000264463.4:c.508C>T p.Pro170Ser p.P170S ENST00000264463 NM_006727.3 170 Ccc/Tcc 0 +CDH16 UCSF GRCh37 16 66944378 66944378 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 4 31 0 ENST00000299752.4:c.1952C>T p.Pro651Leu p.P651L ENST00000299752 NM_001204744.1 651 cCc/cTc 0 +CDH7 UCSF GRCh37 18 63511133 63511133 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 20 110 0 ENST00000397968.2:c.1067G>A p.Gly356Asp p.G356D ENST00000397968 NM_004361.2 356 gGt/gAt 0 +CDK11B UCSF GRCh37 1 1572140 1572140 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 28 43 0 ENST00000407249.3:c.1830C>T p.Asp610= p.D610= ENST00000407249 610 gaC/gaT 0 +CDK13 UCSF GRCh37 7 40134284 40134284 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 48 87 0 ENST00000181839.4:c.4244G>A p.Gly1415Asp p.G1415D ENST00000181839 NM_031267.3 1415 gGt/gAt 0 +CDK13 UCSF GRCh37 7 40134455 40134455 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 25 63 0 ENST00000181839.4:c.4415G>A p.Gly1472Asp p.G1472D ENST00000181839 NM_031267.3 1472 gGc/gAc 0 +CDKL3 UCSF GRCh37 5 133702168 133702168 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 17 76 0 ENST00000265334.4:c.47G>A p.Gly16Glu p.G16E ENST00000265334 NM_001113575.1 16 gGa/gAa 0 +CDKL5 UCSF GRCh37 X 18606251 18606251 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 6 54 66 0 ENST00000379989.3:c.732C>T p.Phe244= p.F244= ENST00000379989 NM_001037343.1 244 ttC/ttT 0 +CDR2L UCSF GRCh37 17 72997562 72997562 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 3 13 0 ENST00000337231.5:c.319G>A p.Ala107Thr p.A107T ENST00000337231 NM_014603.2 107 Gct/Act 0 +CECR2 UCSF GRCh37 22 17978518 17978518 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 10 96 0 ENST00000262608.8:c.359G>A p.Gly120Glu p.G120E ENST00000262608 NM_031413.3 120 gGa/gAa 0 +CELF2 UCSF GRCh37 10 11312703 11312703 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 18 27 0 ENST00000450189.1:c.693G>A p.Gln231= p.Q231= ENST00000450189 NM_006561.3 231 caG/caA 0 +CELF4 UCSF GRCh37 18 34850818 34850818 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.0041 P01_Rec Untested WXS Illumina HiSeq 15 14 17 0 ENST00000420428.2:c.1012G>A p.Val338Met p.V338M ENST00000420428 NM_020180.3 338 Gtg/Atg 0 +CELF4 UCSF GRCh37 18 34854413 34854413 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 8 24 0 ENST00000420428.2:c.662C>T p.Ala221Val p.A221V ENST00000420428 NM_020180.3 221 gCc/gTc 0 +CELSR1 UCSF GRCh37 22 46807624 46807624 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 11 42 0 ENST00000262738.3:c.4644G>A p.Gly1548= p.G1548= ENST00000262738 NM_014246.1 1548 ggG/ggA 0 +CELSR1 UCSF GRCh37 22 46931463 46931463 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 22 32 0 ENST00000262738.3:c.1605G>A p.Lys535= p.K535= ENST00000262738 NM_014246.1 535 aaG/aaA 0 +CELSR2 UCSF GRCh37 1 109795561 109795561 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 30 41 0 ENST00000271332.3:c.2860G>A p.Ala954Thr p.A954T ENST00000271332 NM_001408.2 954 Gcc/Acc 0 +CELSR2 UCSF GRCh37 1 109805763 109805763 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 16 20 0 ENST00000271332.3:c.4709-1G>A p.X1570_splice ENST00000271332 NM_001408.2 0 +CELSR2 UCSF GRCh37 1 109807557 109807557 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 25 51 0 ENST00000271332.3:c.5532C>T p.Thr1844= p.T1844= ENST00000271332 NM_001408.2 1844 acC/acT 0 +CENPC1 UCSF GRCh37 4 68378153 68378153 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 92 21 158 0 ENST00000273853.6:c.1579C>T p.Pro527Ser p.P527S ENST00000273853 NM_001812.2 527 Cca/Tca 0 +CENPJ UCSF GRCh37 13 25457353 25457353 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 76 36 131 0 ENST00000381884.4:c.3979G>A p.Asp1327Asn p.D1327N ENST00000381884 NM_018451.4 1327 Gac/Aac 0 +CEP104 UCSF GRCh37 1 3740108 3740108 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 31 69 0 ENST00000378230.3:c.2383C>T p.Leu795= p.L795= ENST00000378230 NM_014704.3 795 Ctg/Ttg 0 +CEP112 UCSF GRCh37 17 63898345 63898345 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 23 79 0 ENST00000392769.2:c.2088C>T p.Asn696= p.N696= ENST00000392769 NM_145036.3 696 aaC/aaT 0 +CEP95 UCSF GRCh37 17 62504709 62504709 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 153 24 145 0 ENST00000556440.2:c.20-1G>A p.X7_splice ENST00000556440 NM_138363.1 0 +CES2 UCSF GRCh37 16 66975428 66975428 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 7 32 0 ENST00000317091.4:c.1127G>A p.Gly376Glu p.G376E ENST00000317091 NM_003869.5 376 gGa/gAa 0 +CES3 UCSF GRCh37 16 66997748 66997748 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 4 14 0 ENST00000303334.4:c.470C>T p.Ala157Val p.A157V ENST00000303334 NM_024922.5 157 gCc/gTc 0 +CES3 UCSF GRCh37 16 66997711 66997711 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 11 24 0 ENST00000303334.4:c.433G>A p.Val145Ile p.V145I ENST00000303334 NM_024922.5 145 Gta/Ata 0 +CES3 UCSF GRCh37 16 67006758 67006758 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 24 56 0 ENST00000303334.4:c.1522G>A p.Asp508Asn p.D508N ENST00000303334 NM_024922.5 508 Gac/Aac 0 +CETN1 UCSF GRCh37 18 580808 580808 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 11 30 0 ENST00000327228.3:c.400G>A p.Gly134Arg p.G134R ENST00000327228 NM_004066.1 134 Ggg/Agg 0 +CFDP1 UCSF GRCh37 16 75338931 75338931 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 46 144 0 ENST00000283882.3:c.800G>A p.Gly267Glu p.G267E ENST00000283882 NM_006324.2 267 gGg/gAg 0 +CFH UCSF GRCh37 1 196695721 196695721 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 26 106 0 ENST00000367429.4:c.1995G>A p.Met665Ile p.M665I ENST00000367429 NM_000186.3 665 atG/atA 0 +CHAD UCSF GRCh37 17 48545744 48545744 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 3 20 0 ENST00000508540.1:c.431C>T p.Ser144Phe p.S144F ENST00000508540 NM_001267.2 144 tCc/tTc 0 +CHD3 UCSF GRCh37 17 7798765 7798765 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P01_Rec Untested WXS Illumina HiSeq 17 0 ENST00000380358.4:c.1795delC p.Arg599ValfsTer16 p.R599Vfs*16 ENST00000380358 NM_001005271.2 597 Ccc/cc 0 +CHI3L1 UCSF GRCh37 1 203154428 203154428 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 8 32 0 ENST00000255409.3:c.141C>T p.Asp47= p.D47= ENST00000255409 NM_001276.2 47 gaC/gaT 0 +CHIA UCSF GRCh37 1 111863037 111863037 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 5 42 0 ENST00000369740.1:c.1380C>T p.Cys460= p.C460= ENST00000369740 NM_001258001.1 460 tgC/tgT 0 +CHST4 UCSF GRCh37 16 71570829 71570829 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 17 41 0 ENST00000338482.5:c.249G>A p.Lys83= p.K83= ENST00000338482 83 aaG/aaA 0 +CHST5 UCSF GRCh37 16 75563991 75563991 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 9 19 0 ENST00000336257.3:c.292G>A p.Val98Met p.V98M ENST00000336257 NM_024533.4 98 Gtg/Atg 0 +CIITA UCSF GRCh37 16 11000510 11000510 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 7 10 0 ENST00000324288.8:c.1161G>A p.Trp387Ter p.W387* ENST00000324288 NM_000246.3 387 tgG/tgA 0 +CKAP5 UCSF GRCh37 11 46772992 46772992 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 51 84 0 ENST00000529230.1:c.5226C>T p.Val1742= p.V1742= ENST00000529230 1742 gtC/gtT 0 +CKM UCSF GRCh37 19 45821138 45821138 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 3 12 25 0 ENST00000221476.3:c.293G>A p.Gly98Glu p.G98E ENST00000221476 NM_001824.4 98 gGg/gAg 0 +CLASP1 UCSF GRCh37 2 122125250 122125250 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 60 32 63 0 ENST00000263710.4:c.3800A>G p.Tyr1267Cys p.Y1267C ENST00000263710 NM_015282.2 1267 tAc/tGc 0 +CLCN6 UCSF GRCh37 1 11888662 11888662 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 13 67 0 ENST00000346436.6:c.1102C>T p.Pro368Ser p.P368S ENST00000346436 NM_001286.3 368 Ccg/Tcg 0 +CLCN7 UCSF GRCh37 16 1511666 1511666 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 5 9 0 ENST00000382745.4:c.223C>T p.Pro75Ser p.P75S ENST00000382745 NM_001287.5 75 Cct/Tct 0 +CLCNKB UCSF GRCh37 1 16377381 16377381 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 7 9 16 0 ENST00000375679.4:c.1065G>A p.Lys355= p.K355= ENST00000375679 NM_000085.4 355 aaG/aaA 0 +CLDN12 UCSF GRCh37 7 90042263 90042263 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 95 29 65 0 ENST00000535571.1:c.273C>T p.Pro91= p.P91= ENST00000535571 NM_001185072.2 91 ccC/ccT 0 +CLEC16A UCSF GRCh37 16 11272435 11272435 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 8 20 0 ENST00000409790.1:c.3050G>A p.Ser1017Asn p.S1017N ENST00000409790 NM_015226.2 1017 aGc/aAc 0 +CLEC4M UCSF GRCh37 19 7831562 7831562 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 18 29 0 ENST00000327325.5:c.805C>T p.Pro269Ser p.P269S ENST00000327325 NM_001144909.1 269 Ccc/Tcc 0 +CLMN UCSF GRCh37 14 95669764 95669764 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 25 53 0 ENST00000298912.4:c.1922G>A p.Gly641Asp p.G641D ENST00000298912 NM_024734.3 641 gGc/gAc 0 +CLN6 UCSF GRCh37 15 68500543 68500543 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 14 26 0 ENST00000249806.5:c.871C>T p.Pro291Ser p.P291S ENST00000249806 NM_017882.2 291 Ccg/Tcg 0 +CLN8 UCSF GRCh37 8 1719420 1719420 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 4 32 0 ENST00000331222.4:c.200C>T p.Ala67Val p.A67V ENST00000331222 NM_018941.3 67 gCg/gTg 0 +CLNK UCSF GRCh37 4 10566344 10566344 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 62 100 0 ENST00000226951.6:c.350C>T p.Ser117Phe p.S117F ENST00000226951 NM_052964.2 117 tCt/tTt 0 +CLTCL1 UCSF GRCh37 22 19187248 19187248 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 11 49 0 ENST00000263200.10:c.3870C>T p.Tyr1290= p.Y1290= ENST00000263200 NM_007098.3 1290 taC/taT 0 +CMYA5 UCSF GRCh37 5 79034707 79034707 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 105 35 98 0 ENST00000446378.2:c.10119C>T p.Val3373= p.V3373= ENST00000446378 NM_153610.3 3373 gtC/gtT 0 +CNGA3 UCSF GRCh37 2 99008330 99008330 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 8 24 0 ENST00000393504.1:c.570C>T p.Ala190= p.A190= ENST00000393504 NM_001298.2 190 gcC/gcT 0 +CNTD1 UCSF GRCh37 17 40961508 40961508 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 26 43 0 ENST00000588408.1:c.948C>T p.His316= p.H316= ENST00000588408 NM_173478.2 316 caC/caT 0 +CNTNAP2 UCSF GRCh37 7 148106483 148106483 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 27 51 0 ENST00000361727.3:c.3716C>T p.Ala1239Val p.A1239V ENST00000361727 NM_014141.5 1239 gCc/gTc 0 +CNTNAP5 UCSF GRCh37 2 125367388 125367388 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 95 17 69 0 ENST00000431078.1:c.1764G>A p.Glu588= p.E588= ENST00000431078 NM_130773.3 588 gaG/gaA 0 +COASY UCSF GRCh37 17 40715185 40715185 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 13 29 0 ENST00000590958.1:c.632G>A p.Gly211Glu p.G211E ENST00000590958 211 gGg/gAg 0 +COASY UCSF GRCh37 17 40717701 40717701 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 3 19 0 ENST00000590958.1:c.1597G>A p.Asp533Asn p.D533N ENST00000590958 533 Gat/Aat 0 +COG1 UCSF GRCh37 17 71193510 71193510 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 7 48 0 ENST00000299886.4:c.888G>A p.Glu296= p.E296= ENST00000299886 NM_018714.2 296 gaG/gaA 0 +COG5 UCSF GRCh37 7 107167779 107167779 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 10 25 0 ENST00000297135.3:c.534G>A p.Arg178= p.R178= ENST00000297135 NM_006348.3 178 agG/agA 0 +COL10A1 UCSF GRCh37 6 116442681 116442681 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 12 62 0 ENST00000327673.4:c.598G>A p.Gly200Ser p.G200S ENST00000327673 200 Ggt/Agt 0 +COL11A1 UCSF GRCh37 1 103412473 103412473 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 14 4 18 0 ENST00000370096.3:c.3208C>T p.Pro1070Ser p.P1070S ENST00000370096 NM_001854.3 1070 Cca/Tca 0 +COL11A1 UCSF GRCh37 1 103354311 103354311 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 38 78 0 ENST00000370096.3:c.4522C>T p.Pro1508Ser p.P1508S ENST00000370096 NM_001854.3 1508 Cct/Tct 0 +COL17A1 UCSF GRCh37 10 105795079 105795079 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 3 8 0 ENST00000353479.5:c.3561G>A p.Gly1187= p.G1187= ENST00000353479 NM_000494.3 1187 ggG/ggA 0 +COL19A1 UCSF GRCh37 6 70639353 70639353 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 7 18 64 0 ENST00000322773.4:c.427G>A p.Glu143Lys p.E143K ENST00000322773 NM_001858.4 143 Gaa/Aaa 0 +COL25A1 UCSF GRCh37 4 109753579 109753579 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 10 54 0 ENST00000399132.1:c.1667G>A p.Gly556Asp p.G556D ENST00000399132 NM_198721.2 556 gGt/gAt 0 +COL27A1 UCSF GRCh37 9 116931127 116931127 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 120 38 99 0 ENST00000356083.3:c.1292G>A p.Gly431Glu p.G431E ENST00000356083 NM_032888.2 431 gGa/gAa 0 +COL27A1 UCSF GRCh37 9 117029826 117029826 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 7 14 0 ENST00000356083.3:c.3490G>A p.Ala1164Thr p.A1164T ENST00000356083 NM_032888.2 1164 Gcc/Acc 0 +COL4A1 UCSF GRCh37 13 110826345 110826345 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 15 30 0 ENST00000375820.4:c.3407G>A p.Gly1136Asp p.G1136D ENST00000375820 NM_001845.4 1136 gGt/gAt 0 +COL4A3 UCSF GRCh37 2 228134689 228134689 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 15 70 0 ENST00000396578.3:c.1568G>A p.Gly523Glu p.G523E ENST00000396578 NM_000091.4 523 gGa/gAa 0 +COL4A4 UCSF GRCh37 2 227979410 227979410 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 19 83 0 ENST00000396625.3:c.492C>T p.Gly164= p.G164= ENST00000396625 NM_000092.4 164 ggC/ggT 0 +COL4A6 UCSF GRCh37 X 107408677 107408677 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 14 23 0 ENST00000372216.4:c.3734C>T p.Ala1245Val p.A1245V ENST00000372216 NM_001847.2 1245 gCc/gTc 0 +COL5A1 UCSF GRCh37 9 137642402 137642402 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 8 25 0 ENST00000371817.3:c.1509C>T p.Arg503= p.R503= ENST00000371817 NM_001278074.1 503 cgC/cgT 0 +COL6A3 UCSF GRCh37 2 238253370 238253370 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 28 38 0 ENST00000295550.4:c.7291G>A p.Asp2431Asn p.D2431N ENST00000295550 NM_004369.3 2431 Gac/Aac 0 +COL6A3 UCSF GRCh37 2 238287287 238287287 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 11 52 0 ENST00000295550.4:c.2489C>T p.Ala830Val p.A830V ENST00000295550 NM_004369.3 830 gCt/gTt 0 +COPS2 UCSF GRCh37 15 49437259 49437259 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 40 44 93 0 ENST00000299259.6:c.71G>A p.Ser24Asn p.S24N ENST00000299259 24 aGt/aAt 0 +CORIN UCSF GRCh37 4 47605463 47605463 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 6 26 0 ENST00000273857.4:c.2763G>A p.Glu921= p.E921= ENST00000273857 NM_006587.3 921 gaG/gaA 0 +CPA2 UCSF GRCh37 7 129917712 129917712 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 5 19 0 ENST00000222481.4:c.743G>A p.Cys248Tyr p.C248Y ENST00000222481 NM_001869.2 248 tGt/tAt 0 +CPAMD8 UCSF GRCh37 19 17007002 17007002 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 3 9 0 ENST00000443236.1:c.5552G>A p.Gly1851Glu p.G1851E ENST00000443236 NM_015692.2 1851 gGg/gAg 0 +CPAMD8 UCSF GRCh37 19 17100452 17100452 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 7 23 0 ENST00000443236.1:c.1536+1G>A p.X512_splice ENST00000443236 NM_015692.2 0 +CPEB2 UCSF GRCh37 4 15009220 15009220 + intron_variant,non_coding_transcript_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 23 54 0 ENST00000502344.1:n.315-1026C>T *105* ENST00000502344 0 +CPEB4 UCSF GRCh37 5 173378942 173378942 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 32 122 0 ENST00000265085.5:c.1780+1G>A p.X594_splice ENST00000265085 NM_030627.2 0 +CPNE3 UCSF GRCh37 8 87558910 87558910 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 75 61 136 0 ENST00000521271.1:c.819+1G>A p.X273_splice ENST00000521271 NM_003909.3 0 +CPNE4 UCSF GRCh37 3 131624151 131624151 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 6 57 0 ENST00000512055.1:c.137C>T p.Pro46Leu p.P46L ENST00000512055 46 cCc/cTc 0 +CPSF3 UCSF GRCh37 2 9583672 9583672 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 179 20 171 0 ENST00000238112.3:c.1124C>T p.Thr375Ile p.T375I ENST00000238112 NM_016207.3 375 aCt/aTt 0 +CPSF6 UCSF GRCh37 12 69652471 69652471 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 39 51 0 ENST00000435070.2:c.796C>T p.Pro266Ser p.P266S ENST00000435070 NM_007007.2 266 Cct/Tct 0 +CPSF7 UCSF GRCh37 11 61183722 61183722 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 24 31 0 ENST00000340437.4:c.949C>T p.Pro317Ser p.P317S ENST00000340437 NM_024811.3 317 Cct/Tct 0 +CPT1A UCSF GRCh37 11 68574938 68574938 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 6 19 0 ENST00000265641.5:c.450G>A p.Trp150Ter p.W150* ENST00000265641 NM_001876.3 150 tgG/tgA 0 +CPT1B UCSF GRCh37 22 51011961 51011961 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 4 29 0 ENST00000360719.2:c.1154C>T p.Thr385Ile p.T385I ENST00000360719 NM_001145135.1 385 aCt/aTt 0 +CPT1B UCSF GRCh37 22 51012002 51012002 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 6 20 0 ENST00000360719.2:c.1113C>T p.Pro371= p.P371= ENST00000360719 NM_001145135.1 371 ccC/ccT 0 +CPT1B UCSF GRCh37 22 51010435 51010435 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 13 27 0 ENST00000360719.2:c.1575G>A p.Gln525= p.Q525= ENST00000360719 NM_001145135.1 525 caG/caA 0 +CR1 UCSF GRCh37 1 207741179 207741179 + synonymous_variant Silent SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 95 11 114 0 ENST00000367049.4:c.3963T>C p.Cys1321= p.C1321= ENST00000367049 NM_000651.4 1321 tgT/tgC 0 +CREB1 UCSF GRCh37 2 208439999 208439999 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 76 53 88 0 ENST00000432329.2:c.551C>T p.Ala184Val p.A184V ENST00000432329 NM_134442.3 184 gCc/gTc 0 +CREB3L2 UCSF GRCh37 7 137569748 137569748 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 16 53 0 ENST00000330387.6:c.1263C>T p.Ala421= p.A421= ENST00000330387 NM_194071.3 421 gcC/gcT 0 +CRIPAK UCSF GRCh37 4 1388759 1388759 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.037,snp132_rs112233131 P01_Rec Untested WXS Illumina HiSeq 65 10 26 1 ENST00000324803.4:c.460C>T p.Arg154Trp p.R154W ENST00000324803 NM_175918.3 154 Cgg/Tgg 0 +CRYZL1 UCSF GRCh37 21 34997057 34997057 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 36 96 0 ENST00000381554.3:c.76C>T p.Pro26Ser p.P26S ENST00000381554 NM_145858.2 26 Cct/Tct 0 +CSDE1 UCSF GRCh37 1 115261250 115261250 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 8 37 0 ENST00000438362.2:c.2471G>A p.Gly824Glu p.G824E ENST00000438362 NM_001242891.1 824 gGa/gAa 0 +CSRNP3 UCSF GRCh37 2 166514344 166514344 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 37 56 0 ENST00000314499.7:c.222C>T p.Tyr74= p.Y74= ENST00000314499 NM_001172173.1 74 taC/taT 0 +CST9 UCSF GRCh37 20 23586283 23586283 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 29 52 0 ENST00000376971.3:c.219C>T p.Val73= p.V73= ENST00000376971 NM_001008693.2 73 gtC/gtT 0 +CSTF2T UCSF GRCh37 10 53459172 53459172 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 42 92 0 ENST00000331173.4:c.138G>A p.Arg46= p.R46= ENST00000331173 NM_015235.2 46 cgG/cgA 0 +CTBP2 UCSF GRCh37 10 126683197 126683197 + missense_variant Missense_Mutation SNP T T C snp132_rs74341800 P01_Rec Untested WXS Illumina HiSeq 24 5 39 1 ENST00000309035.6:c.2241A>G p.Ile747Met p.I747M ENST00000309035 NM_022802.2 747 atA/atG 0 +CTC1 UCSF GRCh37 17 8138176 8138176 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 10 28 0 ENST00000315684.8:c.1508G>A p.Gly503Glu p.G503E ENST00000315684 NM_025099.5 503 gGa/gAa 0 +CTIF UCSF GRCh37 18 46284567 46284567 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 31 41 0 ENST00000382998.4:c.862G>A p.Asp288Asn p.D288N ENST00000382998 NM_001142397.1 288 Gac/Aac 0 +CTLA4 UCSF GRCh37 2 204732679 204732679 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 53 14 58 0 ENST00000302823.3:c.14G>A p.Gly5Glu p.G5E ENST00000302823 NM_005214.4 5 gGa/gAa 0 +CTNNAL1 UCSF GRCh37 9 111705105 111705105 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 91 46 75 0 ENST00000325551.4:c.2149G>A p.Glu717Lys p.E717K ENST00000325551 NM_003798.2 717 Gaa/Aaa 0 +CTNNAL1 UCSF GRCh37 9 111714757 111714757 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 8 59 0 ENST00000325551.4:c.1647G>A p.Leu549= p.L549= ENST00000325551 NM_003798.2 549 ctG/ctA 0 +CTNNB1 UCSF GRCh37 3 41279535 41279535 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 26 107 0 ENST00000349496.5:c.2105C>T p.Ala702Val p.A702V ENST00000349496 NM_001904.3 702 gCc/gTc 0 +CTNND1 UCSF GRCh37 11 57583390 57583390 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 10 21 0 ENST00000399050.4:c.2812G>A p.Asp938Asn p.D938N ENST00000399050 NM_001085458.1 938 Gac/Aac 0 +CTPS UCSF GRCh37 1 41450499 41450500 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 0 ENST00000372621.4:c.177dup p.Val60CysfsTer4 p.V60Cfs*4 ENST00000372621 NM_001905.2 58 gtt/gtTt 0 +CTR9 UCSF GRCh37 11 10785061 10785061 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 24 46 0 ENST00000361367.2:c.933G>A p.Gln311= p.Q311= ENST00000361367 NM_014633.3 311 caG/caA 0 +CTSL2 UCSF GRCh37 9 99797080 99797080 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 110 50 113 0 ENST00000259470.5:c.833G>A p.Gly278Asp p.G278D ENST00000259470 NM_001333.3 278 gGt/gAt 0 +CTTNBP2NL UCSF GRCh37 1 112999270 112999270 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 54 99 0 ENST00000271277.6:c.1156C>T p.Pro386Ser p.P386S ENST00000271277 NM_018704.2 386 Cca/Tca 0 +CUL4A UCSF GRCh37 13 113897333 113897333 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 48 71 0 ENST00000375440.4:c.1087C>T p.Gln363Ter p.Q363* ENST00000375440 NM_001008895.2 363 Caa/Taa 0 +CUL9 UCSF GRCh37 6 43156361 43156361 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 13 40 0 ENST00000252050.4:c.2088C>T p.Asn696= p.N696= ENST00000252050 NM_015089.2 696 aaC/aaT 0 +CXorf26 UCSF GRCh37 X 75395376 75395376 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 5 21 36 0 ENST00000373358.3:c.225C>T p.Phe75= p.F75= ENST00000373358 NM_016500.3 75 ttC/ttT 0 +CYB5RL UCSF GRCh37 1 54661173 54661173 + synonymous_variant,NMD_transcript_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 3 9 0 ENST00000311841.7:c.117C>T p.Asp39= p.D39= ENST00000311841 39 gaC/gaT 0 +CYLD UCSF GRCh37 16 50810182 50810182 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 19 48 0 ENST00000398568.2:c.1006G>A p.Ala336Thr p.A336T ENST00000398568 NM_001042412.1 336 Gct/Act 0 +CYP20A1 UCSF GRCh37 2 204137398 204137398 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 7 46 0 ENST00000356079.4:c.606G>A p.Trp202Ter p.W202* ENST00000356079 NM_177538.2 202 tgG/tgA 0 +CYP21A2 UCSF GRCh37 6 31974229 31974229 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 3 19 0 ENST00000342991.6:n.817G>A *273* ENST00000342991 0 +CYP26B1 UCSF GRCh37 2 72360198 72360198 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 6 19 0 ENST00000001146.2:c.1100C>T p.Pro367Leu p.P367L ENST00000001146 NM_019885.3 367 cCc/cTc 0 +CYP2A13 UCSF GRCh37 19 41594918 41594918 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 16 22 0 ENST00000330436.3:c.265G>A p.Glu89Lys p.E89K ENST00000330436 NM_000766.4 89 Gag/Aag 0 +CYP2C8 UCSF GRCh37 10 96802705 96802705 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 88 19 66 0 ENST00000371270.3:c.1091C>T p.Thr364Ile p.T364I ENST00000371270 NM_000770.3 364 aCc/aTc 0 +CYP2S1 UCSF GRCh37 19 41700576 41700576 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 10 33 0 ENST00000310054.4:c.305G>A p.Gly102Glu p.G102E ENST00000310054 NM_030622.6 102 gGa/gAa 0 +CYP3A43 UCSF GRCh37 7 99457614 99457614 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 17 82 0 ENST00000222382.5:c.1026+1G>A p.X342_splice ENST00000222382 0 +CYP4A11 UCSF GRCh37 1 47402439 47402439 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 5 27 0 ENST00000310638.4:c.407G>A p.Gly136Glu p.G136E ENST00000310638 NM_000778.3 136 gGg/gAg 0 +CYP4X1 UCSF GRCh37 1 47512236 47512236 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 12 47 0 ENST00000371901.3:c.1171C>T p.Pro391Ser p.P391S ENST00000371901 NM_178033.1 391 Cca/Tca 0 +DAGLB UCSF GRCh37 7 6472571 6472571 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 3 19 0 ENST00000297056.6:c.698G>A p.Ser233Asn p.S233N ENST00000297056 NM_139179.3 233 aGc/aAc 0 +DBH UCSF GRCh37 9 136509382 136509382 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 10 25 0 ENST00000393056.2:c.964C>T p.Pro322Ser p.P322S ENST00000393056 NM_000787.3 322 Cca/Tca 0 +DBH UCSF GRCh37 9 136522333 136522333 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 10 17 0 ENST00000393056.2:c.1704C>T p.Ser568= p.S568= ENST00000393056 NM_000787.3 568 tcC/tcT 0 +DCDC2B UCSF GRCh37 1 32674838 32674838 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 28 30 0 ENST00000409358.1:c.144G>A p.Gln48= p.Q48= ENST00000409358 NM_001099434.1 48 caG/caA 0 +DCDC5 UCSF GRCh37 11 30921143 30921143 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 133 19 142 0 ENST00000303697.4:c.772G>C p.Lys258Asn p.K258N ENST00000303697 258 aaG/aaC 0 +DCHS2 UCSF GRCh37 4 155237124 155237124 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 27 55 0 ENST00000357232.4:c.3671C>A p.Thr1224Asn p.T1224N ENST00000357232 NM_017639.3 1224 aCc/aAc 0 +DDB1 UCSF GRCh37 11 61076544 61076544 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 25 47 0 ENST00000301764.7:c.2572C>T p.Leu858= p.L858= ENST00000301764 NM_001923.4 858 Cta/Tta 0 +DDHD1 UCSF GRCh37 14 53570506 53570506 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 22 75 0 ENST00000323669.5:c.907G>A p.Glu303Lys p.E303K ENST00000323669 NM_001160148.1 303 Gaa/Aaa 0 +DDR1 UCSF GRCh37 6 30864491 30864491 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 23 43 25 0 ENST00000376575.3:c.1718A>G p.Asp573Gly p.D573G ENST00000376575 573 gAc/gGc 0 +DDX11 UCSF GRCh37 12 31256558 31256558 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 13 27 0 ENST00000407793.2:c.2579G>A p.Gly860Glu p.G860E ENST00000407793 NM_030653.3 860 gGa/gAa 0 +DDX3X UCSF GRCh37 X 41203567 41203567 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 11 36 0 ENST00000399959.2:c.940G>A p.Glu314Lys p.E314K ENST00000399959 NM_001193417.1 314 Gaa/Aaa 0 +DDX50 UCSF GRCh37 10 70666491 70666491 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 16 68 0 ENST00000373585.3:c.112C>T p.His38Tyr p.H38Y ENST00000373585 NM_024045.1 38 Cat/Tat 0 +DDX56 UCSF GRCh37 7 44610391 44610391 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 36 45 0 ENST00000258772.5:c.976G>A p.Gly326Ser p.G326S ENST00000258772 NM_001257189.1 326 Ggc/Agc 0 +DENND2A UCSF GRCh37 7 140301329 140301329 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 34 71 0 ENST00000275884.6:c.869G>A p.Arg290Lys p.R290K ENST00000275884 290 aGg/aAg 0 +DENND2A UCSF GRCh37 7 140268573 140268573 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 23 36 0 ENST00000275884.6:c.1581G>A p.Glu527= p.E527= ENST00000275884 527 gaG/gaA 0 +DENND2C UCSF GRCh37 1 115161059 115161059 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 41 135 0 ENST00000393274.1:c.1272G>A p.Lys424= p.K424= ENST00000393274 NM_001256404.1 424 aaG/aaA 0 +DENND3 UCSF GRCh37 8 142176467 142176467 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 23 40 0 ENST00000262585.2:c.1492G>A p.Gly498Ser p.G498S ENST00000262585 NM_014957.2 498 Ggc/Agc 0 +DFNB31 UCSF GRCh37 9 117185744 117185744 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 13 20 0 ENST00000362057.3:c.1476C>T p.Asp492= p.D492= ENST00000362057 NM_001173425.1 492 gaC/gaT 0 +DGKH UCSF GRCh37 13 42799463 42799463 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 98 15 101 0 ENST00000337343.4:c.3574-3772G>A *1192* ENST00000337343 NM_178009.3 0 +DHCR24 UCSF GRCh37 1 55337053 55337053 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 10 19 0 ENST00000371269.3:c.846G>A p.Gly282= p.G282= ENST00000371269 NM_014762.3 282 ggG/ggA 0 +DIEXF UCSF GRCh37 1 210010322 210010322 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 33 77 0 ENST00000491415.2:c.828C>T p.Thr276= p.T276= ENST00000491415 NM_014388.6 276 acC/acT 0 +DIP2C UCSF GRCh37 10 410500 410500 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 3 20 0 ENST00000280886.6:c.2291G>A p.Gly764Glu p.G764E ENST00000280886 NM_014974.2 764 gGg/gAg 0 +DLAT UCSF GRCh37 11 111930758 111930758 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 43 162 0 ENST00000280346.6:c.1646G>A p.Arg549Lys p.R549K ENST00000280346 NM_001931.4 549 aGa/aAa 0 +DLC1 UCSF GRCh37 8 12957987 12957987 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 32 6 26 0 ENST00000276297.4:c.1859C>T p.Ser620Phe p.S620F ENST00000276297 NM_182643.2 620 tCc/tTc 0 +DLC1 UCSF GRCh37 8 12950182 12950182 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 20 13 37 0 ENST00000276297.4:c.3679G>A p.Val1227Met p.V1227M ENST00000276297 NM_182643.2 1227 Gtg/Atg 0 +DLG3 UCSF GRCh37 X 69720346 69720346 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 4 14 0 ENST00000374360.3:c.2171C>T p.Ser724Phe p.S724F ENST00000374360 NM_021120.3 724 tCc/tTc 0 +DLG4 UCSF GRCh37 17 7100192 7100192 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 15 0 ENST00000399510.2:c.1096C>T p.Leu366= p.L366= ENST00000399510 NM_001365.3 366 Ctg/Ttg 0 +DLGAP1 UCSF GRCh37 18 3534464 3534464 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 6 39 0 ENST00000315677.3:c.2207C>T p.Thr736Ile p.T736I ENST00000315677 NM_004746.3 736 aCc/aTc 0 +DMD UCSF GRCh37 X 31697623 31697623 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 5 45 0 ENST00000357033.4:c.7741G>A p.Asp2581Asn p.D2581N ENST00000357033 NM_004007.2 2581 Gat/Aat 0 +DMD UCSF GRCh37 X 31893450 31893450 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 3 32 0 ENST00000357033.4:c.6953C>T p.Ala2318Val p.A2318V ENST00000357033 NM_004007.2 2318 gCt/gTt 0 +DMD UCSF GRCh37 X 32407765 32407765 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 33 59 0 ENST00000357033.4:c.4371G>A p.Lys1457= p.K1457= ENST00000357033 NM_004007.2 1457 aaG/aaA 0 +DMGDH UCSF GRCh37 5 78347287 78347287 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 27 61 0 ENST00000255189.3:c.568G>A p.Asp190Asn p.D190N ENST00000255189 NM_013391.3 190 Gat/Aat 0 +DMGDH UCSF GRCh37 5 78325822 78325822 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 18 57 0 ENST00000255189.3:c.1719C>T p.Pro573= p.P573= ENST00000255189 NM_013391.3 573 ccC/ccT 0 +DMRTC2 UCSF GRCh37 19 42355670 42355670 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 11 45 0 ENST00000269945.3:c.1010G>A p.Gly337Glu p.G337E ENST00000269945 NM_001040283.1 337 gGa/gAa 0 +DMXL1 UCSF GRCh37 5 118484522 118484522 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 18 104 0 ENST00000311085.8:c.3000G>A p.Trp1000Ter p.W1000* ENST00000311085 NM_005509.4 1000 tgG/tgA 0 +DNA2 UCSF GRCh37 10 70204774 70204774 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 25 127 0 ENST00000399180.2:c.1382G>A p.Arg461Lys p.R461K ENST00000399180 461 aGa/aAa 0 +DNAH1 UCSF GRCh37 3 52400863 52400863 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 7 31 0 ENST00000420323.2:c.5725G>A p.Gly1909Ser p.G1909S ENST00000420323 NM_015512.4 1909 Ggc/Agc 0 +DNAH11 UCSF GRCh37 7 21609755 21609755 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 136 32 105 0 ENST00000328843.6:c.1263G>A p.Gln421= p.Q421= ENST00000328843 421 caG/caA 0 +DNAH12 UCSF GRCh37 3 57458321 57458321 + upstream_gene_variant 5'Flank SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 39 93 0 ENST00000459308 0 +DNAH17 UCSF GRCh37 17 76421618 76421618 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 5 24 0 ENST00000389840.5:c.13019C>T p.Pro4340Leu p.P4340L ENST00000389840 4340 cCc/cTc 0 +DNAH3 UCSF GRCh37 16 21132064 21132064 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 8 73 0 ENST00000261383.3:c.1696G>A p.Ala566Thr p.A566T ENST00000261383 NM_017539.1 566 Gca/Aca 0 +DNAH5 UCSF GRCh37 5 13792290 13792290 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 10 89 0 ENST00000265104.4:c.8261G>A p.Gly2754Asp p.G2754D ENST00000265104 NM_001369.2 2754 gGt/gAt 0 +DNAH8 UCSF GRCh37 6 38994438 38994438 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 19 38 0 ENST00000359357.3:c.13180C>T p.Pro4394Ser p.P4394S ENST00000359357 4394 Cct/Tct 0 +DNAH9 UCSF GRCh37 17 11550496 11550496 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 9 57 0 ENST00000262442.4:c.2078C>T p.Thr693Ile p.T693I ENST00000262442 NM_001372.3 693 aCt/aTt 0 +DNAI1 UCSF GRCh37 9 34512186 34512186 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 4 36 0 ENST00000242317.4:c.1391C>T p.Thr464Ile p.T464I ENST00000242317 NM_012144.3 464 aCt/aTt 0 +DNAJA2 UCSF GRCh37 16 47005263 47005263 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 21 72 0 ENST00000317089.5:c.360C>T p.Leu120= p.L120= ENST00000317089 NM_005880.3 120 ctC/ctT 0 +DNAJC10 UCSF GRCh37 2 183627480 183627480 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 39 86 0 ENST00000264065.7:c.2217G>A p.Gly739= p.G739= ENST00000264065 NM_018981.2 739 ggG/ggA 0 +DNAJC12 UCSF GRCh37 10 69565489 69565489 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 56 152 0 ENST00000225171.2:c.354G>A p.Lys118= p.K118= ENST00000225171 NM_021800.2 118 aaG/aaA 0 +DNAJC14 UCSF GRCh37 12 56216254 56216254 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 43 84 0 ENST00000357606.3:c.1801G>A p.Ala601Thr p.A601T ENST00000357606 601 Gct/Act 0 +DNAJC2 UCSF GRCh37 7 102982259 102982259 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 124 22 133 0 ENST00000379263.3:c.207G>A p.Gln69= p.Q69= ENST00000379263 NM_014377.1 69 caG/caA 0 +DNAJC4 UCSF GRCh37 11 64000195 64000195 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 19 35 0 ENST00000321685.3:c.385G>A p.Ala129Thr p.A129T ENST00000321685 NM_005528.3 129 Gca/Aca 0 +DNAJC6 UCSF GRCh37 1 65877089 65877089 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 22 62 0 ENST00000371069.4:c.2791C>T p.Leu931= p.L931= ENST00000371069 NM_001256864.1 931 Ctg/Ttg 0 +DNHD1 UCSF GRCh37 11 6591862 6591862 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 4 23 0 ENST00000254579.6:c.13120G>A p.Asp4374Asn p.D4374N ENST00000254579 NM_144666.2 4374 Gat/Aat 0 +DNM1 UCSF GRCh37 9 130984532 130984532 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 13 30 0 ENST00000372923.3:c.906C>T p.Ser302= p.S302= ENST00000372923 NM_004408.2 302 agC/agT 0 +DNMT3B UCSF GRCh37 20 31386392 31386392 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 13 31 0 ENST00000328111.2:c.1617G>A p.Arg539= p.R539= ENST00000328111 NM_006892.3 539 cgG/cgA 0 +DOCK10 UCSF GRCh37 2 225639660 225639660 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 20 35 0 ENST00000258390.7:c.5975G>A p.Gly1992Glu p.G1992E ENST00000258390 NM_014689.2 1992 gGg/gAg 0 +DOCK3 UCSF GRCh37 3 51315054 51315054 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 7 17 30 0 ENST00000266037.9:c.2692G>A p.Glu898Lys p.E898K ENST00000266037 NM_004947.4 898 Gag/Aag 0 +DOCK4 UCSF GRCh37 7 111584879 111584879 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 56 94 0 ENST00000437633.1:c.831C>T p.His277= p.H277= ENST00000437633 NM_014705.3 277 caC/caT 0 +DOCK5 UCSF GRCh37 8 25257466 25257466 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 70 33 136 0 ENST00000276440.7:c.4744G>A p.Asp1582Asn p.D1582N ENST00000276440 NM_024940.6 1582 Gac/Aac 0 +DOCK9 UCSF GRCh37 13 99461624 99461624 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 7 65 0 ENST00000376460.1:c.5349G>A p.Arg1783= p.R1783= ENST00000376460 NM_015296.2 1783 cgG/cgA 0 +DOPEY2 UCSF GRCh37 21 37586854 37586854 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 66 50 116 0 ENST00000399151.3:c.1129G>A p.Gly377Arg p.G377R ENST00000399151 NM_005128.2 377 Ggg/Agg 0 +DPY19L4 UCSF GRCh37 8 95792605 95792605 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 28 90 0 ENST00000414645.2:c.1594G>A p.Ala532Thr p.A532T ENST00000414645 NM_181787.2 532 Gcc/Acc 0 +DPY19L4 UCSF GRCh37 8 95801990 95801990 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 53 148 0 ENST00000414645.2:c.2024G>A p.Gly675Asp p.G675D ENST00000414645 NM_181787.2 675 gGt/gAt 0 +DPY19L4 UCSF GRCh37 8 95800133 95800133 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 13 64 0 ENST00000414645.2:c.1860C>T p.Ile620= p.I620= ENST00000414645 NM_181787.2 620 atC/atT 0 +DR1 UCSF GRCh37 1 93819517 93819517 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 32 60 0 ENST00000370272.4:c.273G>A p.Leu91= p.L91= ENST00000370272 NM_001938.2 91 ttG/ttA 0 +DSCAML1 UCSF GRCh37 11 117352816 117352816 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 3 12 0 ENST00000321322.6:c.2601G>A p.Glu867= p.E867= ENST00000321322 NM_020693.2 867 gaG/gaA 0 +DSE UCSF GRCh37 6 116757372 116757372 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 6 39 0 ENST00000331677.3:c.1741G>A p.Glu581Lys p.E581K ENST00000331677 581 Gag/Aag 0 +DSG2 UCSF GRCh37 18 29116190 29116190 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 15 97 0 ENST00000261590.8:c.1449C>T p.Gly483= p.G483= ENST00000261590 NM_001943.3 483 ggC/ggT 0 +DSPP UCSF GRCh37 4 88533898 88533898 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 20 81 0 ENST00000399271.1:c.560C>T p.Ala187Val p.A187V ENST00000399271 NM_014208.3 187 gCt/gTt 0 +DST UCSF GRCh37 6 56382342 56382342 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 115 16 114 0 ENST00000244364.6:c.10337G>A p.Arg3446Lys p.R3446K ENST00000244364 NM_015548.4 3446 aGg/aAg 0 +DTNBP1 UCSF GRCh37 6 15523293 15523293 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 132 15 52 0 ENST00000344537.5:c.969G>A p.Glu323= p.E323= ENST00000344537 NM_001271667.1 323 gaG/gaA 0 +DUOX1 UCSF GRCh37 15 45431639 45431639 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 4 31 0 ENST00000321429.4:c.1231C>T p.Pro411Ser p.P411S ENST00000321429 NM_017434.3 411 Cca/Tca 0 +DUOX1 UCSF GRCh37 15 45454105 45454105 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 9 13 0 ENST00000321429.4:c.4026G>A p.Trp1342Ter p.W1342* ENST00000321429 NM_017434.3 1342 tgG/tgA 0 +DUOX1 UCSF GRCh37 15 45439634 45439634 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 6 8 12 0 ENST00000321429.4:c.2326C>T p.Leu776= p.L776= ENST00000321429 NM_017434.3 776 Ctg/Ttg 0 +DUOX2 UCSF GRCh37 15 45386390 45386390 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 27 11 41 0 ENST00000603300.1:c.4605G>A p.Arg1535= p.R1535= ENST00000603300 NM_014080.4 1535 agG/agA 0 +DUSP15 UCSF GRCh37 20 30452768 30452768 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 7 32 0 ENST00000339738.5:c.176C>T p.Pro59Leu p.P59L ENST00000339738 NM_080611.3 59 cCt/cTt 0 +DUSP16 UCSF GRCh37 12 12630433 12630433 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 33 45 0 ENST00000228862.2:c.1332G>A p.Gln444= p.Q444= ENST00000228862 NM_030640.2 444 caG/caA 0 +DYNC1I2 UCSF GRCh37 2 172604285 172604285 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 42 137 0 ENST00000397119.3:c.1804-1G>A p.X602_splice ENST00000397119 NM_001378.2 0 +DYNC2H1 UCSF GRCh37 11 103052580 103052580 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 32 0 ENST00000398093.3:c.6442T>C p.Tyr2148His p.Y2148H ENST00000398093 2148 Tat/Cat 0 +DYRK1A UCSF GRCh37 21 38884787 38884787 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 29 104 0 ENST00000398960.2:c.2245C>T p.Pro749Ser p.P749S ENST00000398960 NM_001396.3 749 Ccc/Tcc 0 +DYRK1A UCSF GRCh37 21 38845044 38845044 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 37 87 0 ENST00000398960.2:c.69C>T p.Phe23= p.F23= ENST00000398960 NM_001396.3 23 ttC/ttT 0 +E2F3 UCSF GRCh37 6 20481556 20481556 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 193 26 134 0 ENST00000346618.3:c.625G>A p.Glu209Lys p.E209K ENST00000346618 NM_001949.4 209 Gaa/Aaa 0 +EBP UCSF GRCh37 X 48385564 48385564 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 9 29 0 ENST00000495186.1:c.360C>T p.Cys120= p.C120= ENST00000495186 NM_006579.2 120 tgC/tgT 0 +ECE1 UCSF GRCh37 1 21573749 21573749 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 8 28 0 ENST00000374893.6:c.1128G>A p.Glu376= p.E376= ENST00000374893 NM_001397.2 376 gaG/gaA 0 +EDIL3 UCSF GRCh37 5 83362330 83362330 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 11 82 0 ENST00000296591.5:c.747C>T p.Ala249= p.A249= ENST00000296591 NM_005711.4 249 gcC/gcT 0 +EFEMP2 UCSF GRCh37 11 65638811 65638811 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 15 32 0 ENST00000307998.6:c.184C>T p.Pro62Ser p.P62S ENST00000307998 NM_016938.4 62 Cct/Tct 0 +EHF UCSF GRCh37 11 34664174 34664174 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 5 26 0 ENST00000531794.1:c.64-1G>A p.X22_splice ENST00000531794 NM_001206616.1 0 +EIF2B5 UCSF GRCh37 3 183858423 183858423 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 6 52 0 ENST00000273783.3:c.1061G>A p.Ser354Asn p.S354N ENST00000273783 NM_003907.2 354 aGc/aAc 0 +EIF4ENIF1 UCSF GRCh37 22 31850321 31850321 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 11 34 0 ENST00000397525.1:c.1321G>A p.Gly441Ser p.G441S ENST00000397525 NM_001164501.1 441 Ggt/Agt 0 +EIF4G1 UCSF GRCh37 3 184045073 184045073 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 4 13 19 0 ENST00000424196.1:c.3519G>A p.Arg1173= p.R1173= ENST00000424196 1173 cgG/cgA 0 +ELANE UCSF GRCh37 19 855960 855960 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 14 19 0 ENST00000590230.1:c.600G>A p.Gly200= p.G200= ENST00000590230 200 ggG/ggA 0 +ELL UCSF GRCh37 19 18572433 18572433 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 3 18 0 ENST00000262809.4:c.699C>T p.Gly233= p.G233= ENST00000262809 NM_006532.3 233 ggC/ggT 0 +ELN UCSF GRCh37 7 73450886 73450886 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 22 34 0 ENST00000252034.7:c.135G>A p.Gly45= p.G45= ENST00000252034 NM_000501.3 45 ggG/ggA 0 +EML3 UCSF GRCh37 11 62378778 62378778 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 12 8 0 ENST00000394773.2:c.233C>T p.Pro78Leu p.P78L ENST00000394773 NM_153265.2 78 cCt/cTt 0 +EML5 UCSF GRCh37 14 89083072 89083072 + missense_variant,splice_region_variant Missense_Mutation SNP A A T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 14 73 0 ENST00000554922.1:c.5794T>A p.Phe1932Ile p.F1932I ENST00000554922 NM_183387.2 1932 Ttt/Att 0 +EMR2 UCSF GRCh37 19 14863278 14863278 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 19 25 0 ENST00000315576.3:c.1651C>T p.Leu551Phe p.L551F ENST00000315576 NM_013447.3 551 Ctc/Ttc 0 +EMR3 UCSF GRCh37 19 14748988 14748988 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 33 53 0 ENST00000253673.5:c.1413C>T p.Gly471= p.G471= ENST00000253673 NM_032571.3 471 ggC/ggT 0 +ENAM UCSF GRCh37 4 71507948 71507948 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 94 16 74 0 ENST00000396073.3:c.805C>T p.Pro269Ser p.P269S ENST00000396073 NM_031889.2 269 Ccc/Tcc 0 +ENGASE UCSF GRCh37 17 77075600 77075600 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 14 43 0 ENST00000579016.1:c.446C>T p.Pro149Leu p.P149L ENST00000579016 NM_001042573.2 149 cCc/cTc 0 +ENOX1 UCSF GRCh37 13 43987009 43987009 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 10 64 0 ENST00000261488.6:c.42C>T p.Pro14= p.P14= ENST00000261488 NM_017993.3 14 ccC/ccT 0 +ENPEP UCSF GRCh37 4 111470771 111470771 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 35 71 0 ENST00000265162.5:c.2313G>A p.Trp771Ter p.W771* ENST00000265162 NM_001977.3 771 tgG/tgA 0 +ENPP3 UCSF GRCh37 6 131973802 131973802 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 88 11 80 0 ENST00000414305.1:c.398G>A p.Cys133Tyr p.C133Y ENST00000414305 133 tGc/tAc 0 +ENTPD4 UCSF GRCh37 8 23297262 23297262 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 18 45 0 ENST00000358689.4:c.1049G>A p.Arg350Lys p.R350K ENST00000358689 NM_001128930.2 350 aGg/aAg 0 +EP300 UCSF GRCh37 22 41523561 41523561 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 32 82 0 ENST00000263253.7:c.977G>A p.Gly326Glu p.G326E ENST00000263253 NM_001429.3 326 gGa/gAa 0 +EPB41L4A UCSF GRCh37 5 111540139 111540139 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 39 86 0 ENST00000261486.5:c.1309C>T p.Pro437Ser p.P437S ENST00000261486 NM_022140.3 437 Cct/Tct 0 +EPCAM UCSF GRCh37 2 47601173 47601173 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 8 33 0 ENST00000263735.4:c.411G>A p.Glu137= p.E137= ENST00000263735 NM_002354.2 137 gaG/gaA 0 +EPG5 UCSF GRCh37 18 43496476 43496476 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 17 18 0 ENST00000282041.5:c.3311C>T p.Thr1104Ile p.T1104I ENST00000282041 NM_020964.2 1104 aCc/aTc 0 +EPHA10 UCSF GRCh37 1 38188718 38188718 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 3 27 0 ENST00000373048.4:c.1955G>A p.Gly652Glu p.G652E ENST00000373048 NM_001099439.1 652 gGa/gAa 0 +EPHA2 UCSF GRCh37 1 16475000 16475000 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 7 18 0 ENST00000358432.5:c.696C>T p.Asp232= p.D232= ENST00000358432 NM_004431.3 232 gaC/gaT 0 +EPHA7 UCSF GRCh37 6 93969092 93969092 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 50 43 69 0 ENST00000369303.4:c.1904T>C p.Ile635Thr p.I635T ENST00000369303 NM_004440.3 635 aTt/aCt 0 +EPHB3 UCSF GRCh37 3 184298559 184298559 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 4 27 33 0 ENST00000330394.2:c.2431G>A p.Ala811Thr p.A811T ENST00000330394 NM_004443.3 811 Gcc/Acc 0 +EPHB6 UCSF GRCh37 7 142563309 142563309 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 4 13 0 ENST00000392957.2:c.1026C>T p.Asn342= p.N342= ENST00000392957 NM_004445.4 342 aaC/aaT 0 +EPS8L3 UCSF GRCh37 1 110294697 110294697 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 15 79 0 ENST00000369805.3:c.1357G>A p.Ala453Thr p.A453T ENST00000369805 NM_139053.2 453 Gcc/Acc 0 +ERBB2 UCSF GRCh37 17 37883152 37883152 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 35 18 32 0 ENST00000269571.5:c.3055G>A p.Asp1019Asn p.D1019N ENST00000269571 1019 Gat/Aat 0 +ERBB2IP UCSF GRCh37 5 65371004 65371004 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 64 57 89 0 ENST00000506030.1:c.3930A>G p.Pro1310= p.P1310= ENST00000506030 1310 ccA/ccG 0 +ERC2 UCSF GRCh37 3 55733445 55733445 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 162 19 95 0 ENST00000288221.6:c.2808G>A p.Gly936= p.G936= ENST00000288221 NM_015576.1 936 ggG/ggA 0 +ERCC6L UCSF GRCh37 X 71426212 71426212 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 44 38 0 ENST00000334463.3:c.2405G>A p.Gly802Asp p.G802D ENST00000334463 NM_017669.2 802 gGt/gAt 0 +ERCC6L UCSF GRCh37 X 71426791 71426791 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 14 45 0 ENST00000334463.3:c.1826C>T p.Thr609Ile p.T609I ENST00000334463 NM_017669.2 609 aCt/aTt 0 +ERI1 UCSF GRCh37 8 8887368 8887368 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 37 92 0 ENST00000523898.1:c.874C>T p.Pro292Ser p.P292S ENST00000523898 292 Cct/Tct 0 +ERI1 UCSF GRCh37 8 8887425 8887425 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 90 15 114 0 ENST00000523898.1:c.931C>T p.Gln311Ter p.Q311* ENST00000523898 311 Cag/Tag 0 +ESAM UCSF GRCh37 11 124623720 124623720 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 10 17 0 ENST00000278927.5:c.995C>T p.Thr332Ile p.T332I ENST00000278927 NM_138961.2 332 aCc/aTc 0 +ESCO2 UCSF GRCh37 8 27634036 27634036 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 13 81 0 ENST00000305188.8:c.211G>A p.Ala71Thr p.A71T ENST00000305188 NM_001017420.2 71 Gca/Aca 0 +ESRP1 UCSF GRCh37 8 95653643 95653643 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 17 113 0 ENST00000433389.2:c.97C>T p.Leu33= p.L33= ENST00000433389 NM_001034915.2 33 Ctg/Ttg 0 +ESRRA UCSF GRCh37 11 64083256 64083256 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 6 36 0 ENST00000405666.1:c.1090G>A p.Ala364Thr p.A364T ENST00000405666 NM_001282450.1 364 Gcc/Acc 0 +ETS2 UCSF GRCh37 21 40194711 40194711 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 7 23 0 ENST00000360214.3:c.1308G>A p.Lys436= p.K436= ENST00000360214 NM_001256295.1 436 aaG/aaA 0 +EVPL UCSF GRCh37 17 74006448 74006448 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 9 20 0 ENST00000301607.3:c.2838G>A p.Arg946= p.R946= ENST00000301607 NM_001988.2 946 agG/agA 0 +EVPL UCSF GRCh37 17 74003406 74003406 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 15 29 0 ENST00000301607.3:c.5880C>T p.Leu1960= p.L1960= ENST00000301607 NM_001988.2 1960 ctC/ctT 0 +EXD2 UCSF GRCh37 14 69704412 69704412 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 3 11 0 ENST00000409018.3:c.1413C>T p.Asn471= p.N471= ENST00000409018 NM_001193361.1 471 aaC/aaT 0 +EXOC1 UCSF GRCh37 4 56768539 56768539 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 63 8 53 0 ENST00000381295.2:c.2367G>A p.Val789= p.V789= ENST00000381295 NM_001024924.1 789 gtG/gtA 0 +EXOC2 UCSF GRCh37 6 489001 489001 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 182 28 99 0 ENST00000230449.4:c.2659C>T p.Leu887Phe p.L887F ENST00000230449 NM_018303.5 887 Ctt/Ttt 0 +EXOSC1 UCSF GRCh37 10 99203044 99203044 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 106 19 106 0 ENST00000370902.3:c.172G>A p.Glu58Lys p.E58K ENST00000370902 NM_016046.3 58 Gaa/Aaa 0 +F5 UCSF GRCh37 1 169484688 169484688 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 98 76 128 0 ENST00000367797.3:c.6522G>A p.Val2174= p.V2174= ENST00000367797 NM_000130.4 2174 gtG/gtA 0 +F5 UCSF GRCh37 1 169510620 169510620 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 146 26 112 0 ENST00000367797.3:c.3708C>T p.Ser1236= p.S1236= ENST00000367797 NM_000130.4 1236 agC/agT 0 +F8 UCSF GRCh37 X 154157439 154157439 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 69 56 0 ENST00000360256.4:c.4626G>A p.Gly1542= p.G1542= ENST00000360256 NM_000132.3 1542 ggG/ggA 0 +FAAH2 UCSF GRCh37 X 57475016 57475016 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 12 42 0 ENST00000374900.4:c.1288G>A p.Ala430Thr p.A430T ENST00000374900 NM_174912.3 430 Gca/Aca 0 +FABP4 UCSF GRCh37 8 82391107 82391107 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 9 71 0 ENST00000256104.4:c.392G>A p.Arg131Lys p.R131K ENST00000256104 NM_001442.2 131 aGa/aAa 0 +FAM108C1 UCSF GRCh37 15 81046697 81046697 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 31 81 0 ENST00000258884.4:c.976C>T p.Leu326Phe p.L326F ENST00000258884 NM_021214.1 326 Ctt/Ttt 0 +FAM117B UCSF GRCh37 2 203589645 203589645 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 112 60 153 0 ENST00000392238.2:c.759G>A p.Glu253= p.E253= ENST00000392238 253 gaG/gaA 0 +FAM129A UCSF GRCh37 1 184765105 184765105 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 12 75 0 ENST00000367511.3:c.1793C>T p.Ala598Val p.A598V ENST00000367511 NM_052966.3 598 gCc/gTc 0 +FAM134C UCSF GRCh37 17 40761264 40761264 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 7 15 0 ENST00000309428.5:c.79G>A p.Gly27Ser p.G27S ENST00000309428 NM_178126.3 27 Ggc/Agc 0 +FAM135A UCSF GRCh37 6 71185377 71185377 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 19 66 0 ENST00000418814.2:c.309C>T p.Thr103= p.T103= ENST00000418814 NM_001162529.1 103 acC/acT 0 +FAM157A UCSF GRCh37 3 197894633 197894633 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 25 1 ENST00000437428.2:n.794G>A *265* ENST00000437428 0 +FAM164A UCSF GRCh37 8 79601489 79601489 + missense_variant Missense_Mutation SNP T T A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 19 89 0 ENST00000263849.4:c.385T>A p.Phe129Ile p.F129I ENST00000263849 NM_016010.2 129 Ttc/Atc 0 +FAM166A UCSF GRCh37 9 140139640 140139640 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 6 9 0 ENST00000344774.4:c.553C>T p.Pro185Ser p.P185S ENST00000344774 NM_001001710.1 185 Ccc/Tcc 0 +FAM173B UCSF GRCh37 5 10227654 10227654 + missense_variant Missense_Mutation SNP C C T snp132_rs3177295 P01_Rec Untested WXS Illumina HiSeq 21 26 47 0 ENST00000511437.1:c.601G>A p.Glu201Lys p.E201K ENST00000511437 NM_199133.3 201 Gag/Aag 0 +FAM179B UCSF GRCh37 14 45481213 45481213 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 28 49 0 ENST00000361577.3:c.3173G>A p.Cys1058Tyr p.C1058Y ENST00000361577 NM_015091.2 1058 tGt/tAt 0 +FAM19A1 UCSF GRCh37 3 68466435 68466435 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 99 15 95 0 ENST00000478136.1:c.124G>A p.Gly42Arg p.G42R ENST00000478136 NM_213609.3 42 Ggg/Agg 0 +FAM26E UCSF GRCh37 6 116836991 116836991 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 19 105 0 ENST00000368599.3:c.769C>T p.Pro257Ser p.P257S ENST00000368599 NM_153711.2 257 Cct/Tct 0 +FAM46C UCSF GRCh37 1 118166409 118166409 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 8 38 0 ENST00000369448.3:c.919C>T p.Leu307Phe p.L307F ENST00000369448 NM_017709.3 307 Ctc/Ttc 0 +FAM48A UCSF GRCh37 13 37598537 37598537 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 8 64 0 ENST00000350612.6:c.1372G>A p.Gly458Ser p.G458S ENST00000350612 NM_001014286.2 458 Ggt/Agt 0 +FAM63A UCSF GRCh37 1 150973040 150973040 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 14 55 0 ENST00000361738.6:c.772G>A p.Val258Ile p.V258I ENST00000361738 NM_001163258.1 258 Gtc/Atc 0 +FAM69B UCSF GRCh37 9 139617831 139617831 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 4 21 0 ENST00000371692.4:c.901G>A p.Ala301Thr p.A301T ENST00000371692 NM_152421.3 301 Gcc/Acc 0 +FAM71A UCSF GRCh37 1 212799161 212799161 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 26 0 ENST00000294829.3:c.942G>A p.Gly314= p.G314= ENST00000294829 NM_153606.3 314 ggG/ggA 0 +FAM71F2 UCSF GRCh37 7 128320204 128320204 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 13 42 0 ENST00000480462.1:c.734+1G>A p.X245_splice ENST00000480462 0 +FAM75A6 UCSF GRCh37 9 43627812 43627812 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 115 26 148 0 ENST00000332857.6:c.875C>T p.Ala292Val p.A292V ENST00000332857 NM_001145196.1 292 gCc/gTc 0 +FAM83B UCSF GRCh37 6 54806653 54806653 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 11 121 0 ENST00000306858.7:c.2884G>A p.Glu962Lys p.E962K ENST00000306858 NM_001010872.2 962 Gaa/Aaa 0 +FAM83B UCSF GRCh37 6 54806562 54806562 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 25 118 0 ENST00000306858.7:c.2793G>A p.Arg931= p.R931= ENST00000306858 NM_001010872.2 931 cgG/cgA 0 +FAM90A1 UCSF GRCh37 12 8374486 8374486 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 10 47 0 ENST00000538603.1:c.1327C>T p.Pro443Ser p.P443S ENST00000538603 NM_018088.3 443 Cca/Tca 0 +FANCA UCSF GRCh37 16 89805354 89805354 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 8 59 0 ENST00000389301.3:c.4196C>T p.Ala1399Val p.A1399V ENST00000389301 NM_000135.2 1399 gCt/gTt 0 +FARP1 UCSF GRCh37 13 99091386 99091386 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 23 35 0 ENST00000319562.6:c.2369G>A p.Ser790Asn p.S790N ENST00000319562 NM_005766.2 790 aGc/aAc 0 +FARS2 UCSF GRCh37 6 5369382 5369382 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 9 41 0 ENST00000324331.6:c.579G>A p.Gln193= p.Q193= ENST00000324331 193 caG/caA 0 +FASTKD1 UCSF GRCh37 2 170386416 170386416 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 6 52 0 ENST00000453153.2:c.2463C>T p.Asn821= p.N821= ENST00000453153 NM_024622.4 821 aaC/aaT 0 +FASTKD3 UCSF GRCh37 5 7863012 7863012 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 151 24 141 0 ENST00000264669.5:c.1623G>A p.Lys541= p.K541= ENST00000264669 NM_024091.3 541 aaG/aaA 0 +FAT1 UCSF GRCh37 4 187509963 187509963 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 37 14 78 0 ENST00000441802.2:c.13550C>T p.Ala4517Val p.A4517V ENST00000441802 NM_005245.3 4517 gCc/gTc 0 +FAT1 UCSF GRCh37 4 187542914 187542914 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 15 52 112 0 ENST00000441802.2:c.4826C>T p.Ser1609Phe p.S1609F ENST00000441802 NM_005245.3 1609 tCt/tTt 0 +FAT1 UCSF GRCh37 4 187627860 187627860 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 71 123 0 ENST00000441802.2:c.3122G>A p.Gly1041Glu p.G1041E ENST00000441802 NM_005245.3 1041 gGg/gAg 0 +FAT3 UCSF GRCh37 11 92086268 92086268 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 94 57 109 0 ENST00000298047.6:c.990G>A p.Lys330= p.K330= ENST00000298047 330 aaG/aaA 0 +FAT4 UCSF GRCh37 4 126240599 126240599 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 45 118 0 ENST00000394329.3:c.3033G>A p.Val1011= p.V1011= ENST00000394329 NM_024582.4 1011 gtG/gtA 0 +FBLN1 UCSF GRCh37 22 45959103 45959103 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 10 22 0 ENST00000327858.6:c.1698-11288C>T *566* ENST00000327858 NM_006486.2 0 +FBLN2 UCSF GRCh37 3 13613057 13613057 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 7 20 0 ENST00000404922.3:c.1202C>T p.Pro401Leu p.P401L ENST00000404922 NM_001004019.1 401 cCc/cTc 0 +FBLN5 UCSF GRCh37 14 92349365 92349365 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 11 26 0 ENST00000342058.4:c.795G>A p.Gln265= p.Q265= ENST00000342058 NM_006329.3 265 caG/caA 0 +FBN1 UCSF GRCh37 15 48717668 48717668 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 12 49 0 ENST00000316623.5:c.7351G>A p.Ala2451Thr p.A2451T ENST00000316623 NM_000138.4 2451 Gct/Act 0 +FBN1 UCSF GRCh37 15 48757772 48757772 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 12 68 0 ENST00000316623.5:c.4935G>A p.Val1645= p.V1645= ENST00000316623 NM_000138.4 1645 gtG/gtA 0 +FBN3 UCSF GRCh37 19 8148151 8148151 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 19 37 0 ENST00000600128.1:c.7193C>T p.Ala2398Val p.A2398V ENST00000600128 2398 gCt/gTt 0 +FBXL5 UCSF GRCh37 4 15627527 15627527 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 24 66 0 ENST00000341285.3:c.1198G>A p.Ala400Thr p.A400T ENST00000341285 NM_001193534.1 400 Gcc/Acc 0 +FBXO18 UCSF GRCh37 10 5965617 5965617 + missense_variant Missense_Mutation SNP G G C NOVEL P01_Rec Untested WXS Illumina HiSeq 40 35 61 0 ENST00000379999.5:c.2509G>C p.Asp837His p.D837H ENST00000379999 NM_032807.4 837 Gat/Cat 0 +FBXO34 UCSF GRCh37 14 55818571 55818571 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 59 107 0 ENST00000313833.4:c.1463G>A p.Gly488Asp p.G488D ENST00000313833 NM_017943.3 488 gGt/gAt 0 +FCER1A UCSF GRCh37 1 159273926 159273926 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 12 75 0 ENST00000368115.1:c.285C>T p.His95= p.H95= ENST00000368115 NM_002001.3 95 caC/caT 0 +FCHO2 UCSF GRCh37 5 72264375 72264375 + synonymous_variant Silent SNP A A T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 30 98 0 ENST00000430046.2:c.84A>T p.Gly28= p.G28= ENST00000430046 NM_138782.2 28 ggA/ggT 0 +FCRLA UCSF GRCh37 1 161680678 161680678 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 5 42 0 ENST00000367959.2:c.277C>T p.Pro93Ser p.P93S ENST00000367959 NM_001184866.1 93 Ccc/Tcc 0 +FER1L5 UCSF GRCh37 2 97370246 97370246 + downstream_gene_variant 3'Flank SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 113 65 128 0 ENST00000377079 NM_001142292.1 0 +FER1L6 UCSF GRCh37 8 125072466 125072466 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 22 78 0 ENST00000522917.1:c.2920G>A p.Asp974Asn p.D974N ENST00000522917 NM_001039112.2 974 Gac/Aac 0 +FFAR2 UCSF GRCh37 19 35941280 35941280 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 13 23 0 ENST00000599180.2:c.664G>A p.Gly222Arg p.G222R ENST00000599180 222 Ggg/Agg 0 +FGA UCSF GRCh37 4 155507088 155507088 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 6 82 0 ENST00000302053.3:c.1493G>A p.Gly498Asp p.G498D ENST00000302053 NM_000508.3 498 gGc/gAc 0 +FH UCSF GRCh37 1 241671969 241671969 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 11 74 0 ENST00000366560.3:c.672G>A p.Glu224= p.E224= ENST00000366560 NM_000143.3 224 gaG/gaA 0 +FHOD3 UCSF GRCh37 18 34320685 34320685 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 7 48 0 ENST00000257209.4:c.3118C>T p.Pro1040Ser p.P1040S ENST00000257209 NM_025135.2 1040 Cct/Tct 0 +FHOD3 UCSF GRCh37 18 34205546 34205546 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 19 40 0 ENST00000257209.4:c.1030G>A p.Ala344Thr p.A344T ENST00000257209 NM_025135.2 344 Gcc/Acc 0 +FKBP10 UCSF GRCh37 17 39975921 39975921 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 5 19 0 ENST00000321562.4:c.1057G>A p.Gly353Arg p.G353R ENST00000321562 NM_021939.3 353 Gga/Aga 0 +FLII UCSF GRCh37 17 18157899 18157899 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 4 15 0 ENST00000327031.4:c.511C>T p.Arg171Cys p.R171C ENST00000327031 NM_002018.3 171 Cgc/Tgc 0 +FLII UCSF GRCh37 17 18149750 18149751 + inframe_insertion In_Frame_Ins INS - - CTC NOVEL P01_Rec Untested WXS Illumina HiSeq 6 0 ENST00000327031.4:c.3079_3080insGGA p.Glu1026_Asn1027insArg p.E1026_N1027insR ENST00000327031 NM_002018.3 1026 gag/gaGAGg 0 +FLNB UCSF GRCh37 3 58108939 58108939 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 27 81 0 ENST00000490882.1:c.3246G>A p.Glu1082= p.E1082= ENST00000490882 NM_001164317.1 1082 gaG/gaA 0 +FMNL2 UCSF GRCh37 2 153496531 153496531 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 12 0 ENST00000288670.9:c.3006C>T p.Leu1002= p.L1002= ENST00000288670 NM_052905.3 1002 ctC/ctT 0 +FN1 UCSF GRCh37 2 216248897 216248897 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 46 82 0 ENST00000354785.4:c.4740C>T p.Ser1580= p.S1580= ENST00000354785 1580 agC/agT 0 +FNDC7 UCSF GRCh37 1 109276039 109276039 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 40 80 0 ENST00000370017.3:c.2025C>T p.Gly675= p.G675= ENST00000370017 NM_001144937.1 675 ggC/ggT 0 +FNIP1 UCSF GRCh37 5 131007197 131007197 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 25 93 0 ENST00000510461.1:c.2939+1G>A p.X980_splice ENST00000510461 NM_133372.2 0 +FOLH1 UCSF GRCh37 11 49221860 49221860 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 54 132 0 ENST00000256999.2:c.358C>T p.Pro120Ser p.P120S ENST00000256999 NM_004476.1 120 Cca/Tca 0 +FOLR1 UCSF GRCh37 11 71906504 71906504 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 45 70 0 ENST00000393679.1:c.357+1G>A p.X119_splice ENST00000393679 0 +FOSB UCSF GRCh37 19 45974128 45974128 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 5 10 14 0 ENST00000353609.3:c.368C>T p.Pro123Leu p.P123L ENST00000353609 NM_006732.2 123 cCt/cTt 0 +FOXB1 UCSF GRCh37 15 60297264 60297264 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 25 26 0 ENST00000396057.4:c.102G>A p.Leu34= p.L34= ENST00000396057 NM_012182.2 34 ctG/ctA 0 +FOXD2 UCSF GRCh37 1 47904249 47904249 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 18 34 0 ENST00000334793.5:c.442C>T p.Leu148= p.L148= ENST00000334793 NM_004474.3 148 Ctg/Ttg 0 +FOXF2 UCSF GRCh37 6 1390553 1390553 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 8 13 0 ENST00000259806.1:c.371G>A p.Ser124Asn p.S124N ENST00000259806 NM_001452.1 124 aGc/aAc 0 +FOXJ3 UCSF GRCh37 1 42657092 42657092 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 35 56 0 ENST00000372572.1:c.1233G>A p.Gln411= p.Q411= ENST00000372572 NM_001198851.1 411 caG/caA 0 +FOXP2 UCSF GRCh37 7 114282468 114282468 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 35 39 0 ENST00000408937.3:c.854G>A p.Gly285Asp p.G285D ENST00000408937 NM_014491.3 285 gGc/gAc 0 +FOXR2 UCSF GRCh37 X 55650852 55650852 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 6 39 0 ENST00000339140.3:c.708G>A p.Trp236Ter p.W236* ENST00000339140 NM_198451.3 236 tgG/tgA 0 +FPGT UCSF GRCh37 1 74670257 74670257 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 55 87 0 ENST00000609362.1:c.526G>A p.Gly176Arg p.G176R ENST00000609362 176 Gga/Aga 0 +FRMD7 UCSF GRCh37 X 131212643 131212643 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 17 49 0 ENST00000298542.4:c.1402C>T p.Arg468Cys p.R468C ENST00000298542 NM_194277.2 468 Cgt/Tgt 0 +FRRS1 UCSF GRCh37 1 100195235 100195235 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 9 24 0 ENST00000287474.5:c.829G>A p.Gly277Arg p.G277R ENST00000287474 NM_001013660.2 277 Ggg/Agg 0 +FSD2 UCSF GRCh37 15 83437672 83437672 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 5 37 0 ENST00000334574.8:c.1513C>T p.Leu505= p.L505= ENST00000334574 505 Ctg/Ttg 0 +FSTL4 UCSF GRCh37 5 132561419 132561419 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 22 42 0 ENST00000265342.7:c.1108C>T p.Pro370Ser p.P370S ENST00000265342 NM_015082.1 370 Ccc/Tcc 0 +FUT9 UCSF GRCh37 6 96651854 96651854 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 27 62 0 ENST00000302103.5:c.823G>A p.Glu275Lys p.E275K ENST00000302103 NM_006581.3 275 Gaa/Aaa 0 +FYB UCSF GRCh37 5 39119705 39119705 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 83 43 151 0 ENST00000540520.1:c.2200G>A p.Glu734Lys p.E734K ENST00000540520 NM_001243093.1 734 Gaa/Aaa 0 +FZD2 UCSF GRCh37 17 42636154 42636154 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 11 24 0 ENST00000315323.3:c.1098G>A p.Glu366= p.E366= ENST00000315323 NM_001466.3 366 gaG/gaA 0 +FZD7 UCSF GRCh37 2 202900847 202900847 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 26 0 ENST00000286201.1:c.1477C>T p.Gln493Ter p.Q493* ENST00000286201 NM_003507.1 493 Cag/Tag 0 +GAB1 UCSF GRCh37 4 144359379 144359379 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 12 43 0 ENST00000262995.4:c.821C>T p.Ser274Phe p.S274F ENST00000262995 NM_207123.2 274 tCt/tTt 0 +GADD45G UCSF GRCh37 9 92220582 92220582 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 4 10 0 ENST00000252506.6:c.156G>A p.Val52= p.V52= ENST00000252506 NM_006705.3 52 gtG/gtA 0 +GAL3ST4 UCSF GRCh37 7 99758503 99758503 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 6 27 0 ENST00000360039.4:c.509C>T p.Ser170Phe p.S170F ENST00000360039 NM_024637.4 170 tCc/tTc 0 +GALNT13 UCSF GRCh37 2 155099216 155099216 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 19 83 0 ENST00000392825.3:c.484C>T p.Leu162Phe p.L162F ENST00000392825 NM_052917.2 162 Ctc/Ttc 0 +GALNTL6 UCSF GRCh37 4 173961168 173961168 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 6 94 0 ENST00000506823.1:c.1723C>T p.Pro575Ser p.P575S ENST00000506823 NM_001034845.2 575 Cct/Tct 0 +GANAB UCSF GRCh37 11 62398076 62398076 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 28 31 0 ENST00000346178.4:c.1449G>A p.Arg483= p.R483= ENST00000346178 NM_198335.3 483 cgG/cgA 0 +GAS2L2 UCSF GRCh37 17 34072163 34072163 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 18 39 0 ENST00000254466.6:c.2353G>A p.Asp785Asn p.D785N ENST00000254466 NM_139285.3 785 Gac/Aac 0 +GAS6 UCSF GRCh37 13 114535664 114535664 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 18 22 0 ENST00000327773.6:c.896G>A p.Arg299Gln p.R299Q ENST00000327773 NM_000820.2 299 cGg/cAg 0 +GATM UCSF GRCh37 15 45656140 45656140 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 8 63 0 ENST00000396659.3:c.1117G>A p.Asp373Asn p.D373N ENST00000396659 NM_001482.2 373 Gat/Aat 0 +GBA2 UCSF GRCh37 9 35741757 35741757 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 4 35 0 ENST00000378103.3:c.698C>T p.Pro233Leu p.P233L ENST00000378103 NM_020944.2 233 cCc/cTc 0 +GBP3 UCSF GRCh37 1 89473487 89473487 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 35 96 0 ENST00000370481.4:c.1708C>T p.Leu570Phe p.L570F ENST00000370481 NM_018284.2 570 Ctt/Ttt 0 +GCDH UCSF GRCh37 19 13007724 13007724 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 5 10 0 ENST00000222214.5:c.853G>A p.Gly285Ser p.G285S ENST00000222214 NM_000159.3 285 Ggt/Agt 0 +GCHFR UCSF GRCh37 15 41059451 41059451 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 14 29 0 ENST00000260447.4:c.159C>T p.Pro53= p.P53= ENST00000260447 NM_005258.2 53 ccC/ccT 0 +GCK UCSF GRCh37 7 44187403 44187403 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 10 17 0 ENST00000345378.2:c.712G>A p.Glu238Lys p.E238K ENST00000345378 NM_033507.1 238 Gag/Aag 0 +GCLC UCSF GRCh37 6 53381010 53381010 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 25 58 0 ENST00000229416.6:c.457C>T p.Pro153Ser p.P153S ENST00000229416 NM_001197115.1 153 Cct/Tct 0 +GDF2 UCSF GRCh37 10 48413747 48413747 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 18 31 0 ENST00000249598.1:c.1121C>T p.Ala374Val p.A374V ENST00000249598 NM_016204.1 374 gCt/gTt 0 +GDPD1 UCSF GRCh37 17 57348345 57348345 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 43 98 0 ENST00000284116.4:c.759G>A p.Trp253Ter p.W253* ENST00000284116 NM_182569.3 253 tgG/tgA 0 +GEMIN5 UCSF GRCh37 5 154292500 154292500 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 7 52 0 ENST00000285873.7:c.1954G>A p.Asp652Asn p.D652N ENST00000285873 NM_001252156.1 652 Gat/Aat 0 +GFER UCSF GRCh37 16 2034833 2034833 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 5 25 0 ENST00000248114.6:c.344C>T p.Ala115Val p.A115V ENST00000248114 NM_005262.2 115 gCc/gTc 0 +GFRA2 UCSF GRCh37 8 21560357 21560357 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 6 12 0 ENST00000524240.1:c.1178G>A p.Ser393Asn p.S393N ENST00000524240 NM_001495.4 393 aGc/aAc 0 +GH2 UCSF GRCh37 17 61957741 61957741 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 31 75 0 ENST00000332800.7:c.*76G>A *26* ENST00000332800 NM_002059.4 0 +GIF UCSF GRCh37 11 59604702 59604702 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 30 63 0 ENST00000257248.2:c.816C>T p.Leu272= p.L272= ENST00000257248 NM_005142.2 272 ctC/ctT 0 +GIGYF1 UCSF GRCh37 7 100280950 100280950 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 4 17 0 ENST00000275732.5:c.2170G>A p.Glu724Lys p.E724K ENST00000275732 NM_022574.4 724 Gaa/Aaa 0 +GIT1 UCSF GRCh37 17 27903626 27903626 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 8 11 16 0 ENST00000394869.3:c.1321G>A p.Ala441Thr p.A441T ENST00000394869 NM_001085454.1 441 Gcc/Acc 0 +GJA8 UCSF GRCh37 1 147380848 147380848 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 23 54 0 ENST00000240986.4:c.766G>A p.Ala256Thr p.A256T ENST00000240986 NM_005267.4 256 Gct/Act 0 +GLG1 UCSF GRCh37 16 74526903 74526903 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 11 81 0 ENST00000205061.5:c.1186G>A p.Ala396Thr p.A396T ENST00000205061 NM_012201.5 396 Gcc/Acc 0 +GLT25D2 UCSF GRCh37 1 183913371 183913371 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 32 59 0 ENST00000361927.4:c.1356G>A p.Leu452= p.L452= ENST00000361927 NM_015101.2 452 ctG/ctA 0 +GMIP UCSF GRCh37 19 19750912 19750912 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 11 14 0 ENST00000203556.4:c.519G>A p.Gln173= p.Q173= ENST00000203556 NM_016573.2 173 caG/caA 0 +GNA14 UCSF GRCh37 9 80040551 80040551 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 85 44 132 0 ENST00000341700.6:c.804C>T p.Phe268= p.F268= ENST00000341700 NM_004297.3 268 ttC/ttT 0 +GNA15 UCSF GRCh37 19 3162822 3162822 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 13 15 0 ENST00000262958.3:c.930G>A p.Arg310= p.R310= ENST00000262958 NM_002068.2 310 agG/agA 0 +GNAL UCSF GRCh37 18 11872322 11872322 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 37 146 0 ENST00000334049.6:c.1087G>A p.Glu363Lys p.E363K ENST00000334049 NM_182978.3 363 Gaa/Aaa 0 +GNAS UCSF GRCh37 20 57415344 57415344 + intron_variant,non_coding_transcript_variant Intron SNP C C T snp132_rs1800901 P01_Rec Untested WXS Illumina HiSeq 25 3 20 0 ENST00000424094.2:n.819+1648G>A *273* ENST00000424094 0 +GNB5 UCSF GRCh37 15 52446146 52446146 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 27 60 0 ENST00000261837.7:c.366C>T p.Ser122= p.S122= ENST00000261837 NM_016194.3 122 agC/agT 0 +GNPNAT1 UCSF GRCh37 14 53248573 53248573 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 17 98 0 ENST00000216410.3:c.274G>A p.Val92Met p.V92M ENST00000216410 NM_198066.3 92 Gtg/Atg 0 +GOLGA1 UCSF GRCh37 9 127642825 127642825 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0015 P01_Rec Untested WXS Illumina HiSeq 70 35 72 0 ENST00000373555.4:c.2288G>A p.Arg763Gln p.R763Q ENST00000373555 NM_002077.3 763 cGg/cAg 0 +GOLGA4 UCSF GRCh37 3 37368568 37368568 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 25 145 0 ENST00000356847.4:c.5257C>T p.Gln1753Ter p.Q1753* ENST00000356847 NM_001172713.1 1753 Cag/Tag 0 +GOLGA4 UCSF GRCh37 3 37367002 37367002 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 46 128 0 ENST00000356847.4:c.3691C>T p.Leu1231= p.L1231= ENST00000356847 NM_001172713.1 1231 Ctg/Ttg 0 +GOLGA6C UCSF GRCh37 15 75562438 75562438 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 24 62 0 ENST00000300576.5:c.1980C>T p.Asn660= p.N660= ENST00000300576 NM_001164404.1 660 aaC/aaT 0 +GORASP2 UCSF GRCh37 2 171806194 171806194 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 32 108 0 ENST00000234160.4:c.290G>A p.Gly97Glu p.G97E ENST00000234160 NM_015530.4 97 gGa/gAa 0 +GPAA1 UCSF GRCh37 8 145139655 145139655 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 26 3 45 0 ENST00000355091.4:c.1041C>T p.Asn347= p.N347= ENST00000355091 NM_003801.3 347 aaC/aaT 0 +GPR107 UCSF GRCh37 9 132837988 132837988 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 22 0 ENST00000372406.1:c.215G>T p.Ser72Ile p.S72I ENST00000372406 NM_001136557.1 72 aGt/aTt 0 +GPR112 UCSF GRCh37 X 135405205 135405205 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 66 43 0 ENST00000394143.1:c.339C>T p.His113= p.H113= ENST00000394143 NM_153834.3 113 caC/caT 0 +GPR137C UCSF GRCh37 14 53098962 53098962 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 44 79 0 ENST00000321662.6:c.802G>A p.Val268Ile p.V268I ENST00000321662 NM_001099652.1 268 Gtc/Atc 0 +GPR158 UCSF GRCh37 10 25886967 25886967 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 141 21 110 0 ENST00000376351.3:c.2412G>A p.Glu804= p.E804= ENST00000376351 NM_020752.2 804 gaG/gaA 0 +GPR172A UCSF GRCh37 8 145583449 145583449 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 23 51 0 ENST00000532887.1:c.297G>A p.Trp99Ter p.W99* ENST00000532887 99 tgG/tgA 0 +GPR176 UCSF GRCh37 15 40093646 40093646 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 24 45 0 ENST00000561100.1:c.1235G>A p.Gly412Glu p.G412E ENST00000561100 NM_007223.2 412 gGa/gAa 0 +GPR19 UCSF GRCh37 12 12814250 12814250 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 45 142 0 ENST00000540510.1:c.1133C>T p.Pro378Leu p.P378L ENST00000540510 378 cCt/cTt 0 +GPR22 UCSF GRCh37 7 107115668 107115668 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 58 143 0 ENST00000304402.4:c.1163C>T p.Ser388Phe p.S388F ENST00000304402 NM_005295.2 388 tCt/tTt 0 +GPR37L1 UCSF GRCh37 1 202092434 202092434 + missense_variant Missense_Mutation SNP C C A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 6 22 1 ENST00000367282.5:c.343C>A p.Gln115Lys p.Q115K ENST00000367282 NM_004767.3 115 Cag/Aag 0 +GPR45 UCSF GRCh37 2 105858490 105858490 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 17 41 0 ENST00000258456.1:c.175G>A p.Val59Met p.V59M ENST00000258456 NM_007227.3 59 Gtg/Atg 0 +GPR64 UCSF GRCh37 X 19032072 19032072 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 8 28 0 ENST00000379869.3:c.831C>T p.Thr277= p.T277= ENST00000379869 NM_001079858.2 277 acC/acT 0 +GPRC6A UCSF GRCh37 6 117127574 117127574 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 21 51 0 ENST00000310357.3:c.1294G>A p.Ala432Thr p.A432T ENST00000310357 NM_148963.2 432 Gct/Act 0 +GPRC6A UCSF GRCh37 6 117130700 117130700 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 27 56 0 ENST00000310357.3:c.275G>A p.Gly92Glu p.G92E ENST00000310357 NM_148963.2 92 gGa/gAa 0 +GPRC6A UCSF GRCh37 6 117127942 117127942 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 54 120 0 ENST00000310357.3:c.926C>T p.Thr309Ile p.T309I ENST00000310357 NM_148963.2 309 aCc/aTc 0 +GPX4 UCSF GRCh37 19 1106459 1106459 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 5 21 0 ENST00000354171.8:c.561+1G>A p.X187_splice ENST00000354171 NM_001039847.1 0 +GPX6 UCSF GRCh37 6 28478643 28478643 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 18 49 0 ENST00000361902.1:c.126G>A p.Glu42= p.E42= ENST00000361902 NM_182701.1 42 gaG/gaA 0 +GREB1 UCSF GRCh37 2 11765424 11765424 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 171 61 112 0 ENST00000381486.2:c.4292G>A p.Gly1431Asp p.G1431D ENST00000381486 NM_014668.3 1431 gGt/gAt 0 +GRHL1 UCSF GRCh37 2 10104452 10104452 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 19 43 0 ENST00000324907.9:c.992C>T p.Ala331Val p.A331V ENST00000324907 NM_198182.2 331 gCt/gTt 0 +GRID1 UCSF GRCh37 10 87406962 87406962 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 35 75 0 ENST00000327946.7:c.2190G>A p.Arg730= p.R730= ENST00000327946 NM_017551.2 730 agG/agA 0 +GRID2 UCSF GRCh37 4 94138039 94138039 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 27 116 0 ENST00000282020.4:c.940G>A p.Asp314Asn p.D314N ENST00000282020 NM_001510.2 314 Gat/Aat 0 +GRID2 UCSF GRCh37 4 94376896 94376896 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 27 70 0 ENST00000282020.4:c.1629C>T p.Tyr543= p.Y543= ENST00000282020 NM_001510.2 543 taC/taT 0 +GRID2 UCSF GRCh37 4 94316793 94316793 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 35 98 0 ENST00000282020.4:c.1281G>A p.Gly427= p.G427= ENST00000282020 NM_001510.2 427 ggG/ggA 0 +GRIK1 UCSF GRCh37 21 31062291 31062291 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 11 35 0 ENST00000399907.1:c.301G>A p.Ala101Thr p.A101T ENST00000399907 NM_000830.3 101 Gct/Act 0 +GRIN1 UCSF GRCh37 9 140058244 140058244 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 17 33 0 ENST00000371553.3:c.2540C>T p.Ala847Val p.A847V ENST00000371553 NM_001185090.1 847 gCc/gTc 0 +GRIP2 UCSF GRCh37 3 14536441 14536441 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 18 0 ENST00000273083.3:n.2945C>T *982* ENST00000273083 0 +GRM1 UCSF GRCh37 6 146720776 146720776 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 21 18 0 ENST00000361719.2:c.2601C>T p.Cys867= p.C867= ENST00000361719 867 tgC/tgT 0 +GRM1 UCSF GRCh37 6 146747734 146747734 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 24 62 0 ENST00000361719.2:c.2661-7274G>A *887* ENST00000361719 0 +GRM2 UCSF GRCh37 3 51749551 51749551 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 18 22 0 ENST00000395052.3:c.1762G>A p.Val588Ile p.V588I ENST00000395052 NM_000839.3 588 Gtc/Atc 0 +GRM8 UCSF GRCh37 7 126882895 126882895 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 26 82 0 ENST00000339582.2:c.364G>A p.Ala122Thr p.A122T ENST00000339582 122 Gca/Aca 0 +GRTP1 UCSF GRCh37 13 113980369 113980369 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 10 17 0 ENST00000375431.4:c.600C>T p.Asp200= p.D200= ENST00000375431 NM_024719.2 200 gaC/gaT 0 +GRXCR1 UCSF GRCh37 4 42895398 42895398 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 77 48 89 0 ENST00000399770.2:c.115T>C p.Ser39Pro p.S39P ENST00000399770 NM_001080476.2 39 Tca/Cca 0 +GRXCR2 UCSF GRCh37 5 145239346 145239346 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 23 57 0 ENST00000377976.1:c.697C>T p.Pro233Ser p.P233S ENST00000377976 NM_001080516.1 233 Cct/Tct 0 +GSG2 UCSF GRCh37 17 3628523 3628523 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 35 82 0 ENST00000325418.4:c.1294G>A p.Ala432Thr p.A432T ENST00000325418 NM_031965.2 432 Gct/Act 0 +GTSE1 UCSF GRCh37 22 46708062 46708062 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 30 61 0 ENST00000454366.1:c.787C>T p.Pro263Ser p.P263S ENST00000454366 NM_016426.6 263 Cct/Tct 0 +GXYLT1 UCSF GRCh37 12 42481737 42481737 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 25 60 0 ENST00000398675.3:c.1174G>A p.Asp392Asn p.D392N ENST00000398675 NM_173601.1 392 Gat/Aat 0 +GXYLT1 UCSF GRCh37 12 42491349 42491349 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 124 14 111 0 ENST00000398675.3:c.1056C>T p.Cys352= p.C352= ENST00000398675 NM_173601.1 352 tgC/tgT 0 +HAP1 UCSF GRCh37 17 39881070 39881070 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 93 11 61 0 ENST00000347901.4:c.1743C>T p.Asn581= p.N581= ENST00000347901 NM_177977.2 581 aaC/aaT 0 +HBS1L UCSF GRCh37 6 135358639 135358639 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 12 69 0 ENST00000367837.5:c.430+2072G>A *144* ENST00000367837 NM_006620.3 0 +HBS1L UCSF GRCh37 6 135360725 135360725 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 100 22 125 0 ENST00000367837.5:c.416G>A p.Gly139Glu p.G139E ENST00000367837 NM_006620.3 139 gGa/gAa 0 +HDAC4 UCSF GRCh37 2 239990216 239990216 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 5 16 0 ENST00000345617.3:c.2823C>T p.Thr941= p.T941= ENST00000345617 NM_006037.3 941 acC/acT 0 +HEATR4 UCSF GRCh37 14 73965842 73965842 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 37 73 0 ENST00000553558.1:c.2289G>A p.Val763= p.V763= ENST00000553558 NM_001220484.1 763 gtG/gtA 0 +HEATR5A UCSF GRCh37 14 31852965 31852965 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 53 0 ENST00000389961.3:c.1340G>A p.Ser447Asn p.S447N ENST00000389961 447 aGt/aAt 0 +HEATR6 UCSF GRCh37 17 58123567 58123567 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 36 103 0 ENST00000184956.6:c.2793C>T p.Ala931= p.A931= ENST00000184956 NM_022070.4 931 gcC/gcT 0 +HECTD1 UCSF GRCh37 14 31592144 31592144 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 107 20 111 0 ENST00000399332.1:c.5091G>A p.Glu1697= p.E1697= ENST00000399332 NM_015382.2 1697 gaG/gaA 0 +HECTD1 UCSF GRCh37 14 31597876 31597876 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 35 71 0 ENST00000399332.1:c.4701C>T p.Ser1567= p.S1567= ENST00000399332 NM_015382.2 1567 agC/agT 0 +HELZ UCSF GRCh37 17 65147165 65147165 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 38 93 0 ENST00000358691.5:c.2353C>T p.Pro785Ser p.P785S ENST00000358691 NM_014877.3 785 Cct/Tct 0 +HERC1 UCSF GRCh37 15 63986511 63986511 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 118 15 98 0 ENST00000443617.2:c.5480G>A p.Gly1827Glu p.G1827E ENST00000443617 NM_003922.3 1827 gGg/gAg 0 +HERC4 UCSF GRCh37 10 69748441 69748441 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 18 142 0 ENST00000395198.3:c.1785G>A p.Lys595= p.K595= ENST00000395198 NM_022079.2 595 aaG/aaA 0 +HGSNAT UCSF GRCh37 8 43046714 43046714 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 45 15 56 0 ENST00000379644.4:c.1226T>C p.Leu409Pro p.L409P ENST00000379644 NM_152419.2 409 cTc/cCc 0 +HINFP UCSF GRCh37 11 119003262 119003262 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 8 36 0 ENST00000350777.2:c.733C>T p.Arg245Trp p.R245W ENST00000350777 NM_198971.2 245 Cgg/Tgg 0 +HINT3 UCSF GRCh37 6 126296071 126296071 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 44 106 0 ENST00000229633.5:c.468C>T p.Gly156= p.G156= ENST00000229633 NM_138571.4 156 ggC/ggT 0 +HIPK1 UCSF GRCh37 1 114512655 114512655 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 102 24 54 0 ENST00000369558.1:c.2849G>A p.Ser950Asn p.S950N ENST00000369558 950 aGc/aAc 0 +HIRA UCSF GRCh37 22 19347002 19347002 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 5 18 0 ENST00000263208.5:c.2091C>T p.Ser697= p.S697= ENST00000263208 NM_003325.3 697 agC/agT 0 +HIVEP1 UCSF GRCh37 6 12123966 12123966 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 105 14 58 0 ENST00000379388.2:c.3938C>T p.Ser1313Phe p.S1313F ENST00000379388 NM_002114.2 1313 tCt/tTt 0 +HIVEP1 UCSF GRCh37 6 12124361 12124361 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 143 30 112 0 ENST00000379388.2:c.4333C>T p.Pro1445Ser p.P1445S ENST00000379388 NM_002114.2 1445 Cct/Tct 0 +HIVEP1 UCSF GRCh37 6 12122439 12122439 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 119 44 103 0 ENST00000379388.2:c.2411G>A p.Ser804Asn p.S804N ENST00000379388 NM_002114.2 804 aGt/aAt 0 +HLA-B UCSF GRCh37 6 31323134 31323134 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.020,snp132_rs1050240 P01_Rec Untested WXS Illumina HiSeq 62 10 26 1 ENST00000412585.2:c.855A>G p.Val285= p.V285= ENST00000412585 NM_005514.6 285 gtA/gtG 0 +HLA-C UCSF GRCh37 6 31239616 31239616 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.000,1000g2011may_all_0.0851,snp132_rs1050445 P01_Rec Untested WXS Illumina HiSeq 26 4 11 0 ENST00000376228.5:c.103G>T p.Ala35Ser p.A35S ENST00000376228 NM_002117.5 35 Gcc/Tcc 0 +HLA-DMA UCSF GRCh37 6 32917118 32917118 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 36 7 20 0 ENST00000374843.4:c.711T>C p.Phe237= p.F237= ENST00000374843 NM_006120.3 237 ttT/ttC 0 +HLA-DPB1 UCSF GRCh37 6 33053616 33053616 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 23 34 0 ENST00000418931.2:c.707G>A p.Gly236Glu p.G236E ENST00000418931 NM_002121.5 236 gGg/gAg 0 +HMCN1 UCSF GRCh37 1 186072691 186072691 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 30 57 0 ENST00000271588.4:c.10661G>A p.Gly3554Glu p.G3554E ENST00000271588 NM_031935.2 3554 gGa/gAa 0 +HMGCS2 UCSF GRCh37 1 120301844 120301844 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 9 65 0 ENST00000369406.3:c.747G>A p.Glu249= p.E249= ENST00000369406 NM_005518.3 249 gaG/gaA 0 +HMOX1 UCSF GRCh37 22 35789569 35789569 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 38 57 0 ENST00000216117.8:c.845C>T p.Ala282Val p.A282V ENST00000216117 NM_002133.2 282 gCt/gTt 0 +HNRNPA1 UCSF GRCh37 12 54677599 54677599 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 122 75 111 0 ENST00000340913.6:c.911G>A p.Ser304Asn p.S304N ENST00000340913 NM_002136.2 304 aGc/aAc 0 +HOGA1 UCSF GRCh37 10 99359865 99359865 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 16 58 0 ENST00000370646.4:c.645G>A p.Gln215= p.Q215= ENST00000370646 NM_138413.3 215 caG/caA 0 +HOMEZ UCSF GRCh37 14 23745354 23745354 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 123 16 72 0 ENST00000357460.5:c.1083G>A p.Lys361= p.K361= ENST00000357460 NM_020834.2 361 aaG/aaA 0 +HOOK2 UCSF GRCh37 19 12881784 12881784 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 17 0 ENST00000397668.3:c.864G>A p.Gln288= p.Q288= ENST00000397668 NM_013312.2 288 caG/caA 0 +HOOK3 UCSF GRCh37 8 42819560 42819560 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 16 107 0 ENST00000307602.4:c.722G>A p.Gly241Glu p.G241E ENST00000307602 NM_032410.3 241 gGa/gAa 0 +HOXA4 UCSF GRCh37 7 27169181 27169181 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 20 24 0 ENST00000360046.5:c.626G>A p.Ser209Asn p.S209N ENST00000360046 NM_002141.4 209 aGt/aAt 0 +HOXB13 UCSF GRCh37 17 46804157 46804157 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 27 35 0 ENST00000290295.7:c.850C>T p.Pro284Ser p.P284S ENST00000290295 NM_006361.5 284 Cct/Tct 0 +HOXC5 UCSF GRCh37 12 54426994 54426994 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 6 39 0 ENST00000312492.2:c.88G>A p.Ala30Thr p.A30T ENST00000312492 NM_018953.2 30 Gcc/Acc 0 +HPD UCSF GRCh37 12 122284968 122284968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 21 58 0 ENST00000289004.4:c.749C>T p.Ser250Phe p.S250F ENST00000289004 NM_002150.2 250 tCc/tTc 0 +HR UCSF GRCh37 8 21979143 21979143 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 11 20 0 ENST00000381418.4:c.2186C>T p.Thr729Ile p.T729I ENST00000381418 NM_005144.4 729 aCc/aTc 0 +HSF4 UCSF GRCh37 16 67201407 67201407 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 33 38 0 ENST00000264009.8:c.759C>T p.Ser253= p.S253= ENST00000264009 NM_001040667.2 253 agC/agT 0 +HSPA5 UCSF GRCh37 9 127998941 127998941 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 33 76 0 ENST00000324460.6:c.1895G>A p.Ser632Asn p.S632N ENST00000324460 NM_005347.4 632 aGc/aAc 0 +HSPG2 UCSF GRCh37 1 22203049 22203049 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 6 11 0 ENST00000374695.3:c.2782G>A p.Gly928Ser p.G928S ENST00000374695 NM_005529.5 928 Ggt/Agt 0 +HSPH1 UCSF GRCh37 13 31712963 31712963 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 33 93 0 ENST00000320027.5:c.2163G>A p.Gln721= p.Q721= ENST00000320027 NM_006644.2 721 caG/caA 0 +HYDIN UCSF GRCh37 16 70902603 70902603 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 15 44 0 ENST00000393567.2:c.11180G>A p.Arg3727Lys p.R3727K ENST00000393567 NM_001270974.1 3727 aGg/aAg 0 +HYOU1 UCSF GRCh37 11 118923365 118923365 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 8 15 0 ENST00000404233.3:c.971C>T p.Ala324Val p.A324V ENST00000404233 NM_001130991.1 324 gCt/gTt 0 +IARS2 UCSF GRCh37 1 220307830 220307830 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 16 51 0 ENST00000302637.5:c.1924G>A p.Ala642Thr p.A642T ENST00000302637 NM_018060.3 642 Gca/Aca 0 +IBTK UCSF GRCh37 6 82882227 82882227 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 10 84 0 ENST00000306270.7:c.3800C>T p.Pro1267Leu p.P1267L ENST00000306270 NM_015525.2 1267 cCc/cTc 0 +ICK UCSF GRCh37 6 52870001 52870001 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 22 51 0 ENST00000356971.3:c.1845C>T p.Ala615= p.A615= ENST00000356971 NM_016513.4 615 gcC/gcT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 47 22 74 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFFO1 UCSF GRCh37 12 6649714 6649714 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 15 0 ENST00000356896.4:c.1627C>T p.Pro543Ser p.P543S ENST00000356896 NM_001039670.2 543 Ccg/Tcg 0 +IFT122 UCSF GRCh37 3 129195505 129195505 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 4 47 0 ENST00000296266.3:c.1162-1G>A p.X388_splice ENST00000296266 NM_052985.3 0 +IGF2BP3 UCSF GRCh37 7 23358756 23358756 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 94 13 104 0 ENST00000258729.3:c.1320+1G>A p.X440_splice ENST00000258729 NM_006547.2 0 +IGFBP3 UCSF GRCh37 7 45956908 45956908 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 35 42 0 ENST00000381083.4:c.552G>A p.Gly184= p.G184= ENST00000381083 184 ggG/ggA 0 +IGFBP5 UCSF GRCh37 2 217543670 217543670 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 14 25 0 ENST00000233813.4:c.470G>A p.Arg157Lys p.R157K ENST00000233813 NM_000599.3 157 aGa/aAa 0 +IGSF10 UCSF GRCh37 3 151166242 151166242 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 63 105 0 ENST00000282466.3:c.1527G>A p.Trp509Ter p.W509* ENST00000282466 NM_178822.4 509 tgG/tgA 0 +IGSF21 UCSF GRCh37 1 18692125 18692125 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 8 23 0 ENST00000251296.1:c.949G>A p.Ala317Thr p.A317T ENST00000251296 NM_032880.4 317 Gcc/Acc 0 +IGSF3 UCSF GRCh37 1 117131413 117131413 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 9 12 0 ENST00000369483.1:c.2403C>T p.Tyr801= p.Y801= ENST00000369483 NM_001542.3 801 taC/taT 0 +IGSF5 UCSF GRCh37 21 41142851 41142851 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 8 42 0 ENST00000380588.4:c.427G>A p.Glu143Lys p.E143K ENST00000380588 NM_001080444.1 143 Gag/Aag 0 +IKBKB UCSF GRCh37 8 42179941 42179941 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 41 49 0 ENST00000520810.1:c.1915G>A p.Asp639Asn p.D639N ENST00000520810 NM_001556.2 639 Gat/Aat 0 +IL12RB2 UCSF GRCh37 1 67796484 67796484 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 75 69 120 0 ENST00000262345.1:c.949C>T p.Pro317Ser p.P317S ENST00000262345 NM_001559.2 317 Cca/Tca 0 +IL13RA2 UCSF GRCh37 X 114245322 114245322 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 7 64 0 ENST00000371936.1:c.591C>T p.Cys197= p.C197= ENST00000371936 197 tgC/tgT 0 +IL1R1 UCSF GRCh37 2 102789257 102789257 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 19 77 0 ENST00000410023.1:c.950C>T p.Thr317Ile p.T317I ENST00000410023 317 aCa/aTa 0 +IL1R2 UCSF GRCh37 2 102626154 102626154 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 40 96 0 ENST00000332549.3:c.198C>T p.Asn66= p.N66= ENST00000332549 NM_004633.3 66 aaC/aaT 0 +IL1RAPL2 UCSF GRCh37 X 104728355 104728355 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 5 41 0 ENST00000372582.1:c.748C>T p.Pro250Ser p.P250S ENST00000372582 NM_017416.1 250 Cca/Tca 0 +IL1RN UCSF GRCh37 2 113885288 113885288 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 30 53 0 ENST00000259206.5:c.96G>A p.Gly32= p.G32= ENST00000259206 NM_173841.2 32 ggG/ggA 0 +IL26 UCSF GRCh37 12 68618974 68618974 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 11 102 0 ENST00000229134.4:c.318C>T p.Arg106= p.R106= ENST00000229134 NM_018402.1 106 cgC/cgT 0 +IL2RA UCSF GRCh37 10 6063440 6063440 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 22 49 0 ENST00000379959.3:c.583+1G>A p.X195_splice ENST00000379959 NM_000417.2 0 +IL3 UCSF GRCh37 5 131398045 131398045 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 142 40 97 0 ENST00000296870.2:c.245G>A p.Arg82Lys p.R82K ENST00000296870 NM_000588.3 82 aGg/aAg 0 +IL36B UCSF GRCh37 2 113788669 113788669 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 27 58 0 ENST00000259213.4:c.77G>A p.Gly26Glu p.G26E ENST00000259213 NM_014438.4 26 gGa/gAa 0 +IL6R UCSF GRCh37 1 154401885 154401885 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 5 21 0 ENST00000368485.3:c.299G>A p.Gly100Asp p.G100D ENST00000368485 NM_000565.3 100 gGc/gAc 0 +IMP5 UCSF GRCh37 17 43922988 43922988 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 17 28 0 ENST00000329196.5:c.716C>T p.Ala239Val p.A239V ENST00000329196 NM_175882.2 239 gCc/gTc 0 +INPP5D UCSF GRCh37 2 234085968 234085968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 30 61 0 ENST00000359570.5:c.2011G>A p.Val671Met p.V671M ENST00000359570 671 Gtg/Atg 0 +INPP5F UCSF GRCh37 10 121586293 121586293 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 25 119 0 ENST00000361976.2:c.2400C>T p.Leu800= p.L800= ENST00000361976 NM_014937.3 800 ctC/ctT 0 +INPPL1 UCSF GRCh37 11 71942216 71942216 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 16 50 0 ENST00000298229.2:c.1480G>A p.Asp494Asn p.D494N ENST00000298229 NM_001567.3 494 Gat/Aat 0 +INSM2 UCSF GRCh37 14 36004874 36004874 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 9 13 0 ENST00000307169.3:c.1416C>T p.Cys472= p.C472= ENST00000307169 NM_032594.3 472 tgC/tgT 0 +INSRR UCSF GRCh37 1 156819111 156819111 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 21 31 0 ENST00000368195.3:c.1371G>A p.Glu457= p.E457= ENST00000368195 NM_014215.2 457 gaG/gaA 0 +INTS1 UCSF GRCh37 7 1523477 1523477 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 5 25 0 ENST00000404767.3:c.3442G>A p.Asp1148Asn p.D1148N ENST00000404767 NM_001080453.2 1148 Gac/Aac 0 +IP6K3 UCSF GRCh37 6 33690912 33690912 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 76 9 44 0 ENST00000451316.1:c.818G>A p.Arg273Lys p.R273K ENST00000451316 NM_001142883.1 273 aGa/aAa 0 +IPO11 UCSF GRCh37 5 61762983 61762983 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 28 97 0 ENST00000409296.3:c.662C>T p.Ala221Val p.A221V ENST00000409296 NM_001134779.1 221 gCc/gTc 0 +IPO9 UCSF GRCh37 1 201823974 201823974 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 8 68 0 ENST00000361565.4:c.834C>T p.Asn278= p.N278= ENST00000361565 NM_018085.4 278 aaC/aaT 0 +IRAK3 UCSF GRCh37 12 66620604 66620604 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 109 26 130 0 ENST00000261233.4:c.755G>A p.Arg252Lys p.R252K ENST00000261233 NM_007199.2 252 aGa/aAa 0 +IREB2 UCSF GRCh37 15 78758799 78758799 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 6 78 0 ENST00000258886.8:c.597C>T p.Ile199= p.I199= ENST00000258886 NM_004136.2 199 atC/atT 0 +IRF2 UCSF GRCh37 4 185310032 185310032 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 13 71 0 ENST00000393593.3:c.930C>T p.Asp310= p.D310= ENST00000393593 NM_002199.3 310 gaC/gaT 0 +IRS4 UCSF GRCh37 X 107977413 107977413 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 7 39 0 ENST00000372129.2:c.2162C>T p.Ala721Val p.A721V ENST00000372129 NM_003604.2 721 gCt/gTt 0 +ISLR UCSF GRCh37 15 74467567 74467567 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 11 14 0 ENST00000249842.3:c.368C>T p.Ala123Val p.A123V ENST00000249842 NM_005545.3 123 gCc/gTc 0 +ISM1 UCSF GRCh37 20 13251231 13251231 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 38 86 0 ENST00000262487.4:c.219C>T p.Asp73= p.D73= ENST00000262487 NM_080826.1 73 gaC/gaT 0 +ITGA7 UCSF GRCh37 12 56092242 56092242 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 9 17 0 ENST00000553804.1:c.1129C>T p.Leu377Phe p.L377F ENST00000553804 NM_001144996.1 377 Ctc/Ttc 0 +ITGA8 UCSF GRCh37 10 15617487 15617487 + splice_donor_variant Splice_Site SNP C C A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 10 38 1 ENST00000378076.3:c.2478+1G>T p.X826_splice ENST00000378076 NM_003638.1 0 +ITGA8 UCSF GRCh37 10 15639251 15639251 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 13 104 0 ENST00000378076.3:c.2166G>A p.Arg722= p.R722= ENST00000378076 NM_003638.1 722 agG/agA 0 +ITGAD UCSF GRCh37 16 31419115 31419115 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 9 25 0 ENST00000389202.2:c.887C>T p.Ala296Val p.A296V ENST00000389202 NM_005353.2 296 gCc/gTc 0 +ITGAL UCSF GRCh37 16 30507834 30507834 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 22 30 0 ENST00000356798.6:c.1779G>A p.Gly593= p.G593= ENST00000356798 NM_002209.2 593 ggG/ggA 0 +ITGAL UCSF GRCh37 16 30529162 30529162 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 9 43 0 ENST00000356798.6:c.3078G>A p.Arg1026= p.R1026= ENST00000356798 NM_002209.2 1026 agG/agA 0 +ITGAX UCSF GRCh37 16 31366602 31366602 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 3 14 0 ENST00000268296.4:c.27C>T p.Leu9= p.L9= ENST00000268296 NM_000887.3 9 ctC/ctT 0 +ITGB2 UCSF GRCh37 21 46311833 46311833 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 9 14 0 ENST00000397850.2:c.1303G>A p.Asp435Asn p.D435N ENST00000397850 435 Gac/Aac 0 +ITPKA UCSF GRCh37 15 41794648 41794648 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 12 13 0 ENST00000260386.5:c.1057G>A p.Glu353Lys p.E353K ENST00000260386 NM_002220.2 353 Gag/Aag 0 +IYD UCSF GRCh37 6 150713488 150713488 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 50 116 0 ENST00000229447.5:c.378C>T p.Ala126= p.A126= ENST00000229447 NM_001164694.1 126 gcC/gcT 0 +JAKMIP1 UCSF GRCh37 4 6043926 6043926 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 49 76 0 ENST00000409021.3:c.2057C>T p.Ala686Val p.A686V ENST00000409021 NM_001099433.1 686 gCc/gTc 0 +JAKMIP1 UCSF GRCh37 4 6080714 6080714 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 10 21 0 ENST00000409021.3:c.1254G>A p.Arg418= p.R418= ENST00000409021 NM_001099433.1 418 cgG/cgA 0 +JMJD1C UCSF GRCh37 10 64958453 64958453 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 31 75 0 ENST00000399262.2:c.5311G>A p.Asp1771Asn p.D1771N ENST00000399262 NM_032776.1 1771 Gat/Aat 0 +JRKL UCSF GRCh37 11 96123920 96123920 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 21 71 0 ENST00000458427.1:c.107G>A p.Gly36Glu p.G36E ENST00000458427 NM_003772.3 36 gGa/gAa 0 +KANK1 UCSF GRCh37 9 732573 732573 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 42 94 0 ENST00000382303.1:c.3201G>A p.Met1067Ile p.M1067I ENST00000382303 NM_001256876.1 1067 atG/atA 0 +KAT5 UCSF GRCh37 11 65480933 65480933 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 4 14 0 ENST00000341318.4:c.499C>T p.Leu167Phe p.L167F ENST00000341318 NM_182710.2 167 Ctc/Ttc 0 +KCMF1 UCSF GRCh37 2 85276592 85276592 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 69 76 0 ENST00000409785.4:c.705G>A p.Gln235= p.Q235= ENST00000409785 NM_020122.4 235 caG/caA 0 +KCNC1 UCSF GRCh37 11 17794140 17794140 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 21 96 0 ENST00000265969.6:c.1499G>A p.Arg500Lys p.R500K ENST00000265969 NM_001112741.1 500 aGa/aAa 0 +KCNC4 UCSF GRCh37 1 110765873 110765873 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 10 32 0 ENST00000369787.3:c.966C>T p.Ile322= p.I322= ENST00000369787 NM_004978.4 322 atC/atT 0 +KCNE1 UCSF GRCh37 21 35821789 35821789 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 12 19 0 ENST00000337385.3:c.144C>T p.Leu48= p.L48= ENST00000337385 NM_001270403.1 48 ctC/ctT 0 +KCNH2 UCSF GRCh37 7 150648065 150648065 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 7 14 0 ENST00000262186.5:c.2089C>T p.Leu697Phe p.L697F ENST00000262186 NM_000238.3 697 Ctc/Ttc 0 +KCNH6 UCSF GRCh37 17 61613299 61613299 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 3 16 0 ENST00000583023.1:c.1371C>T p.Pro457= p.P457= ENST00000583023 NM_030779.3 457 ccC/ccT 0 +KCNJ1 UCSF GRCh37 11 128709396 128709396 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 37 81 0 ENST00000392664.2:c.800C>T p.Thr267Ile p.T267I ENST00000392664 NM_000220.4 267 aCa/aTa 0 +KCNJ13 UCSF GRCh37 2 233633281 233633281 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 103 18 90 0 ENST00000233826.3:c.703C>T p.Pro235Ser p.P235S ENST00000233826 NM_002242.4 235 Cca/Tca 0 +KCNJ5 UCSF GRCh37 11 128781514 128781514 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 12 78 0 ENST00000529694.1:c.346G>A p.Gly116Ser p.G116S ENST00000529694 NM_000890.3 116 Ggt/Agt 0 +KCNK3 UCSF GRCh37 2 26950561 26950561 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 26 57 0 ENST00000302909.3:c.310G>A p.Asp104Asn p.D104N ENST00000302909 NM_002246.2 104 Gat/Aat 0 +KCNK6 UCSF GRCh37 19 38817548 38817548 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 18 57 0 ENST00000263372.3:c.638C>T p.Ser213Phe p.S213F ENST00000263372 NM_004823.1 213 tCc/tTc 0 +KCNK6 UCSF GRCh37 19 38817379 38817379 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 30 61 0 ENST00000263372.3:c.469C>T p.Leu157= p.L157= ENST00000263372 NM_004823.1 157 Ctg/Ttg 0 +KCNMA1 UCSF GRCh37 10 79397125 79397125 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 5 9 0 ENST00000404857.1:c.276C>T p.Ala92= p.A92= ENST00000404857 NM_001161353.1 92 gcC/gcT 0 +KCNQ3 UCSF GRCh37 8 133192525 133192525 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 5 26 0 ENST00000388996.4:c.656G>A p.Gly219Asp p.G219D ENST00000388996 NM_004519.3 219 gGc/gAc 0 +KCTD18 UCSF GRCh37 2 201369581 201369581 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 9 60 0 ENST00000359878.3:c.262C>T p.Leu88= p.L88= ENST00000359878 NM_152387.2 88 Cta/Tta 0 +KDM6B UCSF GRCh37 17 7755606 7755606 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 23 0 ENST00000254846.5:c.4420G>A p.Ala1474Thr p.A1474T ENST00000254846 NM_001080424.1 1474 Gcc/Acc 0 +KDM6B UCSF GRCh37 17 7750671 7750671 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 13 18 0 ENST00000254846.5:c.1158C>T p.Ala386= p.A386= ENST00000254846 NM_001080424.1 386 gcC/gcT 0 +KHDRBS1 UCSF GRCh37 1 32503455 32503455 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 43 87 0 ENST00000327300.7:c.925C>T p.Pro309Ser p.P309S ENST00000327300 NM_006559.2 309 Cct/Tct 0 +KHDRBS1 UCSF GRCh37 1 32498872 32498872 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 24 69 0 ENST00000327300.7:c.708C>T p.Pro236= p.P236= ENST00000327300 NM_006559.2 236 ccC/ccT 0 +KHDRBS2 UCSF GRCh37 6 62611213 62611213 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 27 79 0 ENST00000281156.4:c.547G>A p.Asp183Asn p.D183N ENST00000281156 NM_152688.2 183 Gac/Aac 0 +KHSRP UCSF GRCh37 19 6416415 6416415 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 9 12 0 ENST00000398148.3:c.1492C>T p.Pro498Ser p.P498S ENST00000398148 NM_003685.2 498 Cct/Tct 0 +KIAA0100 UCSF GRCh37 17 26962186 26962186 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 54 126 1 ENST00000528896.2:c.2419C>T p.Pro807Ser p.P807S ENST00000528896 NM_014680.3 807 Cct/Tct 0 +KIAA0226 UCSF GRCh37 3 197401911 197401911 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 3 19 0 ENST00000296343.5:c.2897C>T p.Ala966Val p.A966V ENST00000296343 NM_014687.1 966 gCc/gTc 0 +KIAA0319L UCSF GRCh37 1 35972241 35972241 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 108 27 108 0 ENST00000325722.3:c.638G>A p.Gly213Asp p.G213D ENST00000325722 NM_024874.4 213 gGt/gAt 0 +KIAA0513 UCSF GRCh37 16 85121913 85121913 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 21 36 0 ENST00000566428.1:c.1218G>A p.Glu406= p.E406= ENST00000566428 NM_001286565.1 406 gaG/gaA 0 +KIAA0564 UCSF GRCh37 13 42164844 42164844 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 32 58 0 ENST00000379310.3:c.5044G>A p.Ala1682Thr p.A1682T ENST00000379310 NM_015058.1 1682 Gcc/Acc 0 +KIAA0586 UCSF GRCh37 14 58965622 58965622 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 89 24 100 0 ENST00000354386.6:c.4271C>T p.Ser1424Phe p.S1424F ENST00000354386 NM_001244189.1 1424 tCt/tTt 0 +KIAA1033 UCSF GRCh37 12 105527557 105527557 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 67 120 0 ENST00000332180.5:c.1209G>A p.Gln403= p.Q403= ENST00000332180 NM_015275.1 403 caG/caA 0 +KIAA1191 UCSF GRCh37 5 175777694 175777694 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 28 33 0 ENST00000298569.4:c.381G>A p.Leu127= p.L127= ENST00000298569 NM_020444.3 127 ctG/ctA 0 +KIAA1239 UCSF GRCh37 4 37327621 37327621 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 30 91 0 ENST00000309447.5:c.215G>A p.Arg72Lys p.R72K ENST00000309447 NM_001144990.1 72 aGa/aAa 0 +KIAA1244 UCSF GRCh37 6 138655542 138655542 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 30 35 0 ENST00000251691.4:c.5559G>A p.Gln1853= p.Q1853= ENST00000251691 NM_020340.4 1853 caG/caA 0 +KIAA1539 UCSF GRCh37 9 35107943 35107943 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 5 27 0 ENST00000378561.1:c.329G>A p.Gly110Glu p.G110E ENST00000378561 110 gGa/gAa 0 +KIAA1715 UCSF GRCh37 2 176804319 176804319 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 26 70 0 ENST00000272748.4:c.773G>A p.Arg258Lys p.R258K ENST00000272748 NM_030650.1 258 aGa/aAa 0 +KIAA1751 UCSF GRCh37 1 1887143 1887143 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 10 80 0 ENST00000493964.1:c.12G>A p.Glu4= p.E4= ENST00000493964 4 gaG/gaA 0 +KIAA1755 UCSF GRCh37 20 36867969 36867969 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 13 37 0 ENST00000279024.4:c.1708G>A p.Gly570Ser p.G570S ENST00000279024 NM_001029864.1 570 Ggt/Agt 0 +KIAA1755 UCSF GRCh37 20 36870058 36870058 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 14 77 0 ENST00000279024.4:c.475G>A p.Gly159Arg p.G159R ENST00000279024 NM_001029864.1 159 Gga/Aga 0 +KIAA1958 UCSF GRCh37 9 115422322 115422322 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 8 23 0 ENST00000337530.6:c.2124G>A p.Arg708= p.R708= ENST00000337530 NM_001287038.1 708 agG/agA 0 +KIF13B UCSF GRCh37 8 28984764 28984764 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 63 132 0 ENST00000524189.1:c.3097G>A p.Val1033Ile p.V1033I ENST00000524189 NM_015254.3 1033 Gtc/Atc 0 +KIF18A UCSF GRCh37 11 28058011 28058011 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 104 12 101 0 ENST00000263181.6:c.2149C>T p.Pro717Ser p.P717S ENST00000263181 NM_031217.3 717 Ccg/Tcg 0 +KIF1C UCSF GRCh37 17 4925549 4925549 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 8 15 0 ENST00000320785.5:c.2173G>A p.Val725Ile p.V725I ENST00000320785 NM_006612.5 725 Gtt/Att 0 +KIF2C UCSF GRCh37 1 45223768 45223768 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 27 49 0 ENST00000372224.4:c.1180G>A p.Gly394Ser p.G394S ENST00000372224 NM_006845.3 394 Ggc/Agc 0 +KIF3C UCSF GRCh37 2 26204031 26204031 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 10 15 0 ENST00000264712.3:c.756G>A p.Arg252= p.R252= ENST00000264712 NM_002254.6 252 agG/agA 0 +KIF4A UCSF GRCh37 X 69561757 69561757 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 8 45 0 ENST00000374403.3:c.1242C>T p.Ala414= p.A414= ENST00000374403 NM_012310.4 414 gcC/gcT 0 +KLHDC2 UCSF GRCh37 14 50247481 50247481 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 25 101 0 ENST00000298307.5:c.944C>T p.Thr315Ile p.T315I ENST00000298307 NM_014315.2 315 aCc/aTc 0 +KLHL13 UCSF GRCh37 X 117053549 117053549 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 46 68 0 ENST00000539496.1:c.514G>A p.Glu172Lys p.E172K ENST00000539496 NM_001168299.1 172 Gaa/Aaa 0 +KLHL25 UCSF GRCh37 15 86312642 86312642 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 5 21 0 ENST00000337975.5:c.400G>A p.Asp134Asn p.D134N ENST00000337975 NM_022480.3 134 Gat/Aat 0 +KLK7 UCSF GRCh37 19 51483713 51483713 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 6 10 18 0 ENST00000391807.1:c.252G>A p.Thr84= p.T84= ENST00000391807 NM_139277.2 84 acG/acA 0 +KLRAQ1 UCSF GRCh37 2 48718230 48718230 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 37 79 0 ENST00000294952.8:c.1520G>A p.Gly507Glu p.G507E ENST00000294952 NM_001135629.2 507 gGa/gAa 0 +KLRC4-KLRK1 UCSF GRCh37 12 10525748 10525748 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 36 66 0 ENST00000240618.6:c.616C>T p.Pro206Ser p.P206S ENST00000240618 NM_007360.3 206 Cca/Tca 0 +KRBA2 UCSF GRCh37 17 8273222 8273222 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 95 21 74 0 ENST00000331336.2:c.709C>T p.Gln237Ter p.Q237* ENST00000331336 NM_213597.2 237 Cag/Tag 0 +KREMEN1 UCSF GRCh37 22 29533386 29533386 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 10 45 0 ENST00000327813.5:c.688C>T p.Pro230Ser p.P230S ENST00000327813 NM_032045.4 230 Cct/Tct 0 +KRI1 UCSF GRCh37 19 10672368 10672368 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 12 70 0 ENST00000312962.6:c.481G>A p.Glu161Lys p.E161K ENST00000312962 NM_023008.3 161 Gag/Aag 0 +KRT31 UCSF GRCh37 17 39552765 39552765 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 13 33 0 ENST00000251645.2:c.495C>T p.Ile165= p.I165= ENST00000251645 NM_002277.2 165 atC/atT 0 +KRT34 UCSF GRCh37 17 39534360 39534360 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 10 33 0 ENST00000394001.1:c.1262G>A p.Gly421Asp p.G421D ENST00000394001 NM_021013.3 421 gGc/gAc 0 +KRT5 UCSF GRCh37 12 52909602 52909602 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 25 70 0 ENST00000252242.4:c.1454G>A p.Gly485Glu p.G485E ENST00000252242 NM_000424.3 485 gGa/gAa 0 +KRT6B UCSF GRCh37 12 52845458 52845458 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 33 73 0 ENST00000252252.3:c.405C>T p.Ile135= p.I135= ENST00000252252 NM_005555.3 135 atC/atT 0 +KRT85 UCSF GRCh37 12 52756677 52756677 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 28 46 0 ENST00000257901.3:c.1038C>T p.Ile346= p.I346= ENST00000257901 NM_002283.3 346 atC/atT 0 +KRTAP1-5 UCSF GRCh37 17 39183012 39183012 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 5 28 0 ENST00000361883.5:c.396C>T p.Pro132= p.P132= ENST00000361883 NM_031957.1 132 ccC/ccT 0 +KRTAP10-7 UCSF GRCh37 21 46021353 46021353 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 73 12 54 0 ENST00000380102.2:c.832C>T p.Pro278Ser p.P278S ENST00000380102 NM_198689.2 278 Cct/Tct 0 +KRTAP5-4 UCSF GRCh37 11 1642838 1642838 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 12 48 0 ENST00000399682.1:c.486G>A p.Lys162= p.K162= ENST00000399682 NM_001012709.1 162 aaG/aaA 0 +KRTAP6-3 UCSF GRCh37 21 31965042 31965042 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 9 22 0 ENST00000391624.1:c.257G>A p.Gly86Asp p.G86D ENST00000391624 NM_181605.3 86 gGc/gAc 0 +KSR1 UCSF GRCh37 17 25932612 25932612 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 3 11 0 ENST00000398988.3:c.1422G>A p.Glu474= p.E474= ENST00000398988 NM_014238.1 474 gaG/gaA 0 +LAMA1 UCSF GRCh37 18 6999530 6999530 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 7 23 0 ENST00000389658.3:c.4577G>A p.Gly1526Glu p.G1526E ENST00000389658 NM_005559.3 1526 gGg/gAg 0 +LAMA1 UCSF GRCh37 18 7034641 7034641 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 24 78 0 ENST00000389658.3:c.1888C>T p.Pro630Ser p.P630S ENST00000389658 NM_005559.3 630 Cct/Tct 0 +LAMA2 UCSF GRCh37 6 129636958 129636958 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 72 29 111 0 ENST00000421865.2:c.3787G>A p.Glu1263Lys p.E1263K ENST00000421865 NM_001079823.1 1263 Gaa/Aaa 0 +LAMA2 UCSF GRCh37 6 129581855 129581855 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 97 16 73 0 ENST00000421865.2:c.2097-1G>A p.X699_splice ENST00000421865 NM_001079823.1 0 +LAMB1 UCSF GRCh37 7 107621127 107621127 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 37 81 0 ENST00000222399.6:c.806G>A p.Gly269Glu p.G269E ENST00000222399 NM_002291.2 269 gGa/gAa 0 +LAMB1 UCSF GRCh37 7 107591753 107591753 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 9 21 0 ENST00000222399.6:c.3309C>T p.Cys1103= p.C1103= ENST00000222399 NM_002291.2 1103 tgC/tgT 0 +LAMC2 UCSF GRCh37 1 183184600 183184600 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 13 42 0 ENST00000264144.4:c.281C>T p.Ala94Val p.A94V ENST00000264144 NM_005562.2 94 gCt/gTt 0 +LANCL3 UCSF GRCh37 X 37515001 37515001 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 22 13 36 0 ENST00000378619.3:c.634T>C p.Tyr212His p.Y212H ENST00000378619 NM_001170331.1 212 Tat/Cat 0 +LARGE UCSF GRCh37 22 34157444 34157444 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 28 83 0 ENST00000354992.2:c.20G>A p.Gly7Glu p.G7E ENST00000354992 NM_004737.4 7 gGg/gAg 0 +LCAT UCSF GRCh37 16 67976808 67976808 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 9 39 0 ENST00000264005.5:c.383G>A p.Gly128Asp p.G128D ENST00000264005 NM_000229.1 128 gGc/gAc 0 +LCLAT1 UCSF GRCh37 2 30790968 30790968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 16 86 0 ENST00000309052.4:c.668G>A p.Gly223Glu p.G223E ENST00000309052 NM_182551.3 223 gGa/gAa 0 +LCN10 UCSF GRCh37 9 139635381 139635381 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 6 17 0 ENST00000497771.1:c.382G>A p.Ala128Thr p.A128T ENST00000497771 NM_001001712.2 128 Gcc/Acc 0 +LCN2 UCSF GRCh37 9 130911921 130911921 + synonymous_variant Silent SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 59 14 23 0 ENST00000373017.1:c.117G>A p.Gln39= p.Q39= ENST00000373017 39 caG/caA 0 +LDHB UCSF GRCh37 12 21788613 21788613 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 59 21 63 0 ENST00000396076.1:c.868C>T p.Leu290= p.L290= ENST00000396076 NM_001174097.1 290 Ctg/Ttg 0 +LEO1 UCSF GRCh37 15 52252231 52252231 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 36 69 0 ENST00000299601.5:c.1025G>A p.Gly342Glu p.G342E ENST00000299601 NM_138792.2 342 gGa/gAa 0 +LFNG UCSF GRCh37 7 2552829 2552829 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 15 77 0 ENST00000402506.1:c.86G>A p.Arg29Lys p.R29K ENST00000402506 NM_001166355.1 29 aGg/aAg 0 +LGALS12 UCSF GRCh37 11 63283765 63283765 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 8 14 0 ENST00000340246.5:c.914G>A p.Gly305Glu p.G305E ENST00000340246 305 gGg/gAg 0 +LGALS3 UCSF GRCh37 14 55604841 55604841 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 15 27 0 ENST00000254301.9:c.97G>A p.Ala33Thr p.A33T ENST00000254301 NM_002306.3 33 Gca/Aca 0 +LGI1 UCSF GRCh37 10 95557376 95557376 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 83 11 103 0 ENST00000371418.4:c.1490C>T p.Ser497Phe p.S497F ENST00000371418 NM_005097.2 497 tCc/tTc 0 +LGI3 UCSF GRCh37 8 22006117 22006117 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 6 9 0 ENST00000306317.2:c.1203C>T p.Ile401= p.I401= ENST00000306317 NM_139278.2 401 atC/atT 0 +LIG1 UCSF GRCh37 19 48665530 48665530 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 23 155 0 ENST00000263274.7:c.96G>A p.Glu32= p.E32= ENST00000263274 NM_000234.1 32 gaG/gaA 0 +LIMK2 UCSF GRCh37 22 31668561 31668561 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 9 48 0 ENST00000340552.4:c.1366G>A p.Val456Met p.V456M ENST00000340552 NM_001031801.1 456 Gtg/Atg 0 +LIPE UCSF GRCh37 19 42911853 42911853 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 8 0 ENST00000244289.4:c.1747C>T p.Pro583Ser p.P583S ENST00000244289 NM_005357.2 583 Ccc/Tcc 0 +LLPH UCSF GRCh37 12 66517628 66517628 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 124 16 164 0 ENST00000266604.2:c.382G>A p.Ala128Thr p.A128T ENST00000266604 NM_032338.3 128 Gcc/Acc 0 +LNP1 UCSF GRCh37 3 100174747 100174747 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0011 P01_Rec Untested WXS Illumina HiSeq 47 12 116 0 ENST00000383693.3:c.514C>T p.Leu172= p.L172= ENST00000383693 NM_001085451.1 172 Ctg/Ttg 0 +LNX1 UCSF GRCh37 4 54424114 54424114 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 15 27 0 ENST00000263925.7:c.380+15676C>T *127* ENST00000263925 NM_001126328.2 0 +LOC100289561 UCSF GRCh37 7 102016320 102016320 + 5_prime_UTR_variant 5'UTR SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 47 72 0 ENST00000496391.1:c.-623G>A *208* ENST00000496391 0 +LOC200726 UCSF GRCh37 2 207509296 207509296 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 3 13 0 ENST00000543490.1:n.511C>T *171* ENST00000543490 0 +LOC554223 UCSF GRCh37 6 29759888 29759888 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 15 23 0 ENST00000320533.2:n.961G>A *321* ENST00000320533 0 +LPA UCSF GRCh37 6 160968838 160968838 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 86 11 89 0 ENST00000447678.1:c.5287G>A p.Ala1763Thr p.A1763T ENST00000447678 NM_005577.2 1763 Gca/Aca 0 +LPA UCSF GRCh37 6 161026196 161026196 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 95 151 0 ENST00000447678.1:c.2827G>A p.Gly943Arg p.G943R ENST00000447678 NM_005577.2 943 Gga/Aga 0 +LPCAT4 UCSF GRCh37 15 34657243 34657243 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 13 27 0 ENST00000314891.6:c.444C>T p.Ser148= p.S148= ENST00000314891 NM_153613.2 148 tcC/tcT 0 +LPHN2 UCSF GRCh37 1 82435041 82435041 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 73 57 111 0 ENST00000319517.6:c.2652C>T p.Phe884= p.F884= ENST00000319517 NM_012302.2 884 ttC/ttT 0 +LPHN3 UCSF GRCh37 4 62758677 62758677 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 17 56 0 ENST00000514591.1:c.1579+1G>A p.X527_splice ENST00000514591 0 +LPIN1 UCSF GRCh37 2 11922351 11922351 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 32 82 0 ENST00000449576.2:c.1129G>A p.Glu377Lys p.E377K ENST00000449576 NM_001261428.1 377 Gag/Aag 0 +LRBA UCSF GRCh37 4 151765869 151765869 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 30 77 0 ENST00000357115.3:c.4402G>A p.Gly1468Arg p.G1468R ENST00000357115 NM_006726.4 1468 Gga/Aga 0 +LRBA UCSF GRCh37 4 151818947 151818947 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 6 43 0 ENST00000357115.3:c.1948G>A p.Glu650Lys p.E650K ENST00000357115 NM_006726.4 650 Gaa/Aaa 0 +LRFN3 UCSF GRCh37 19 36431118 36431118 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0018 P01_Rec Untested WXS Illumina HiSeq 17 9 10 0 ENST00000588831.1:c.791C>T p.Ala264Val p.A264V ENST00000588831 264 gCg/gTg 0 +LRIF1 UCSF GRCh37 1 111494283 111494283 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 127 76 137 0 ENST00000369763.4:c.1223C>T p.Ser408Phe p.S408F ENST00000369763 NM_018372.3 408 tCc/tTc 0 +LRIG1 UCSF GRCh37 3 66434672 66434672 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 28 74 0 ENST00000273261.3:c.1814C>T p.Pro605Leu p.P605L ENST00000273261 NM_015541.2 605 cCc/cTc 0 +LRIG2 UCSF GRCh37 1 113655109 113655109 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 90 57 110 0 ENST00000361127.5:c.1807T>C p.Ser603Pro p.S603P ENST00000361127 NM_014813.1 603 Tct/Cct 0 +LRIT2 UCSF GRCh37 10 85982122 85982122 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 18 28 0 ENST00000372113.4:c.1207G>A p.Ala403Thr p.A403T ENST00000372113 NM_001017924.2 403 Gcc/Acc 0 +LRP2 UCSF GRCh37 2 170094605 170094605 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 19 39 0 ENST00000263816.3:c.4502G>A p.Arg1501Lys p.R1501K ENST00000263816 NM_004525.2 1501 aGa/aAa 0 +LRRC39 UCSF GRCh37 1 100620671 100620671 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 30 130 0 ENST00000370138.1:c.748C>T p.Leu250Phe p.L250F ENST00000370138 NM_001256385.1 250 Ctt/Ttt 0 +LRRC39 UCSF GRCh37 1 100620731 100620731 + missense_variant Missense_Mutation SNP G G C NOVEL P01_Rec Untested WXS Illumina HiSeq 33 9 74 1 ENST00000370138.1:c.688C>G p.Gln230Glu p.Q230E ENST00000370138 NM_001256385.1 230 Caa/Gaa 0 +LRRFIP1 UCSF GRCh37 2 238672239 238672240 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 0 ENST00000392000.4:c.1886dup p.Asn629LysfsTer12 p.N629Kfs*12 ENST00000392000 NM_001137552.1 628 gaa/gaAa 0 +LTF UCSF GRCh37 3 46492162 46492162 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 6 14 33 0 ENST00000231751.4:c.705G>A p.Glu235= p.E235= ENST00000231751 NM_002343.3 235 gaG/gaA 0 +LUZP1 UCSF GRCh37 1 23418565 23418565 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 101 63 109 0 ENST00000302291.4:c.2190C>T p.Leu730= p.L730= ENST00000302291 730 ctC/ctT 0 +LYG2 UCSF GRCh37 2 99870748 99870748 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 11 54 0 ENST00000333017.2:c.-25G>A p.X9_splice ENST00000333017 NM_175735.3 0 +LYPD3 UCSF GRCh37 19 43965763 43965763 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 3 17 0 ENST00000244333.3:c.781G>A p.Ala261Thr p.A261T ENST00000244333 NM_014400.2 261 Gcc/Acc 0 +LYST UCSF GRCh37 1 235933476 235933476 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 48 100 0 ENST00000389794.3:c.5906C>T p.Thr1969Ile p.T1969I ENST00000389794 1969 aCt/aTt 0 +MACC1 UCSF GRCh37 7 20199857 20199857 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 13 65 0 ENST00000400331.5:c.127C>T p.Pro43Ser p.P43S ENST00000400331 NM_182762.3 43 Cca/Tca 0 +MACC1 UCSF GRCh37 7 20193893 20193893 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 44 32 58 0 ENST00000400331.5:c.2269T>C p.Leu757= p.L757= ENST00000400331 NM_182762.3 757 Tta/Cta 0 +MADD UCSF GRCh37 11 47305933 47305933 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 13 50 0 ENST00000311027.5:c.1974C>T p.Asp658= p.D658= ENST00000311027 NM_003682.3 658 gaC/gaT 0 +MAGEC1 UCSF GRCh37 X 140994939 140994939 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 87 57 0 ENST00000285879.4:c.1749C>T p.Ser583= p.S583= ENST00000285879 NM_005462.4 583 agC/agT 0 +MAGI1 UCSF GRCh37 3 65416464 65416464 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 10 68 0 ENST00000402939.2:c.1456G>A p.Val486Met p.V486M ENST00000402939 NM_001033057.1 486 Gtg/Atg 0 +MAGI1 UCSF GRCh37 3 65456070 65456070 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 12 66 0 ENST00000402939.2:c.847C>T p.Pro283Ser p.P283S ENST00000402939 NM_001033057.1 283 Cct/Tct 0 +MAML1 UCSF GRCh37 5 179201692 179201692 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 12 33 0 ENST00000292599.3:c.2865G>A p.Leu955= p.L955= ENST00000292599 NM_014757.4 955 ctG/ctA 0 +MAML3 UCSF GRCh37 4 140812018 140812018 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 14 81 0 ENST00000509479.2:c.572G>A p.Arg191Gln p.R191Q ENST00000509479 NM_018717.4 191 cGa/cAa 0 +MAMLD1 UCSF GRCh37 X 149638978 149638978 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 38 29 0 ENST00000432680.2:c.1058G>A p.Ser353Asn p.S353N ENST00000432680 NM_001177465.2 353 aGc/aAc 0 +MAN1B1 UCSF GRCh37 9 139995469 139995469 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 122 20 39 0 ENST00000371589.4:c.929C>T p.Ala310Val p.A310V ENST00000371589 NM_016219.4 310 gCc/gTc 0 +MAP1B UCSF GRCh37 5 71492237 71492237 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 17 34 0 ENST00000296755.7:c.3055G>A p.Glu1019Lys p.E1019K ENST00000296755 NM_005909.3 1019 Gag/Aag 0 +MAP1B UCSF GRCh37 5 71492669 71492669 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 46 0 ENST00000296755.7:c.3487A>G p.Thr1163Ala p.T1163A ENST00000296755 NM_005909.3 1163 Acc/Gcc 0 +MAP2K1 UCSF GRCh37 15 66735651 66735651 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 21 64 0 ENST00000307102.5:c.472G>A p.Ala158Thr p.A158T ENST00000307102 NM_002755.3 158 Gct/Act 0 +MAP2K5 UCSF GRCh37 15 67873162 67873162 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 10 107 0 ENST00000178640.5:c.322+1G>A p.X108_splice ENST00000178640 NM_145160.2 0 +MAP3K1 UCSF GRCh37 5 56178158 56178158 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 79 12 102 0 ENST00000399503.3:c.3131C>T p.Pro1044Leu p.P1044L ENST00000399503 NM_005921.1 1044 cCa/cTa 0 +MAP3K14 UCSF GRCh37 17 43364087 43364087 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 7 24 0 ENST00000344686.2:n.969C>T *323* ENST00000344686 0 +MAP3K9 UCSF GRCh37 14 71197444 71197444 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 11 31 0 ENST00000555993.2:c.3010G>A p.Glu1004Lys p.E1004K ENST00000555993 NM_033141.2 1004 Gag/Aag 0 +MAPK8IP3 UCSF GRCh37 16 1817179 1817179 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 6 18 0 ENST00000250894.4:c.3115C>T p.Leu1039= p.L1039= ENST00000250894 NM_015133.3 1039 Cta/Tta 0 +MARCH3 UCSF GRCh37 5 126214081 126214081 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 10 14 0 ENST00000308660.5:c.399G>A p.Leu133= p.L133= ENST00000308660 NM_178450.4 133 ctG/ctA 0 +MARK1 UCSF GRCh37 1 220805553 220805553 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 121 24 165 0 ENST00000366917.4:c.1020C>T p.Val340= p.V340= ENST00000366917 NM_001286124.1 340 gtC/gtT 0 +MASP1 UCSF GRCh37 3 186961306 186961306 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 7 73 0 ENST00000296280.6:c.1194G>A p.Gln398= p.Q398= ENST00000296280 NM_139125.3 398 caG/caA 0 +MAT1A UCSF GRCh37 10 82036304 82036304 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 42 46 0 ENST00000372213.3:c.596G>A p.Arg199His p.R199H ENST00000372213 NM_000429.2 199 cGc/cAc 0 +MBD2 UCSF GRCh37 18 51729304 51729304 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 129 17 92 0 ENST00000256429.3:c.702+2064C>T *234* ENST00000256429 NM_003927.4 0 +MCTS1 UCSF GRCh37 X 119742162 119742162 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 43 0 ENST00000371315.3:c.348C>T p.Gly116= p.G116= ENST00000371315 NM_001137554.1 116 ggC/ggT 0 +MDGA1 UCSF GRCh37 6 37612308 37612308 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 7 21 0 ENST00000434837.3:c.2366C>T p.Thr789Ile p.T789I ENST00000434837 NM_153487.3 789 aCt/aTt 0 +MDM1 UCSF GRCh37 12 68724946 68724946 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 116 58 138 0 ENST00000303145.7:c.74C>T p.Ser25Phe p.S25F ENST00000303145 NM_017440.4 25 tCt/tTt 0 +MDN1 UCSF GRCh37 6 90353891 90353891 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 23 55 0 ENST00000369393.3:c.16624G>A p.Val5542Ile p.V5542I ENST00000369393 5542 Gta/Ata 0 +MECOM UCSF GRCh37 3 168834238 168834238 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 47 75 0 ENST00000264674.3:c.1053G>A p.Arg351= p.R351= ENST00000264674 NM_001105077.3 351 agG/agA 0 +MED23 UCSF GRCh37 6 131944578 131944578 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 27 55 0 ENST00000368068.3:c.309C>T p.Asn103= p.N103= ENST00000368068 NM_004830.3 103 aaC/aaT 0 +MED6 UCSF GRCh37 14 71063384 71063384 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 14 49 0 ENST00000256379.5:c.218C>T p.Ala73Val p.A73V ENST00000256379 NM_005466.2 73 gCt/gTt 0 +MEF2D UCSF GRCh37 1 156453081 156453081 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 8 47 0 ENST00000348159.4:c.4G>A p.Gly2Arg p.G2R ENST00000348159 NM_005920.3 2 Ggg/Agg 0 +MEGF11 UCSF GRCh37 15 66206268 66206268 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 6 28 0 ENST00000409699.2:c.2517C>T p.Ser839= p.S839= ENST00000409699 839 agC/agT 0 +MEGF9 UCSF GRCh37 9 123370235 123370235 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 157 37 128 0 ENST00000373930.3:c.1141C>T p.Pro381Ser p.P381S ENST00000373930 NM_001080497.2 381 Ccg/Tcg 0 +METTL21D UCSF GRCh37 14 50583152 50583152 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 7 15 0 ENST00000395860.2:c.119G>A p.Cys40Tyr p.C40Y ENST00000395860 NM_024558.2 40 tGc/tAc 0 +METTL22 UCSF GRCh37 16 8729153 8729153 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 3 18 0 ENST00000381920.3:c.684G>A p.Arg228= p.R228= ENST00000381920 NM_024109.2 228 cgG/cgA 0 +MFGE8 UCSF GRCh37 15 89444857 89444857 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 5 23 0 ENST00000268150.8:c.795C>T p.Ser265= p.S265= ENST00000268150 NM_005928.2 265 tcC/tcT 0 +MFN1 UCSF GRCh37 3 179096384 179096384 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 6 37 0 ENST00000471841.1:c.1444C>T p.Pro482Ser p.P482S ENST00000471841 NM_033540.2 482 Cca/Tca 0 +MFSD11 UCSF GRCh37 17 74771222 74771222 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 20 73 0 ENST00000588460.1:c.1018G>A p.Gly340Arg p.G340R ENST00000588460 NM_001242534.1 340 Gga/Aga 0 +MFSD6L UCSF GRCh37 17 8700813 8700813 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 9 17 0 ENST00000329805.4:c.1626G>A p.Gln542= p.Q542= ENST00000329805 NM_152599.3 542 caG/caA 0 +MGAM UCSF GRCh37 7 141734145 141734145 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 9 50 0 ENST00000549489.2:c.1753C>T p.Leu585= p.L585= ENST00000549489 NM_004668.2 585 Ctg/Ttg 0 +MGAT5 UCSF GRCh37 2 135185983 135185983 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 16 46 0 ENST00000409645.1:c.1842G>A p.Gln614= p.Q614= ENST00000409645 614 caG/caA 0 +MGLL UCSF GRCh37 3 127441406 127441406 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 9 25 0 ENST00000265052.5:c.266G>A p.Gly89Asp p.G89D ENST00000265052 NM_001256585.1 89 gGc/gAc 0 +MICAL1 UCSF GRCh37 6 109770019 109770019 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 20 45 0 ENST00000358807.3:c.1580G>A p.Gly527Glu p.G527E ENST00000358807 NM_022765.3 527 gGa/gAa 0 +MICALL1 UCSF GRCh37 22 38318007 38318007 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 11 12 0 ENST00000215957.6:c.598C>T p.Pro200Ser p.P200S ENST00000215957 NM_033386.3 200 Cct/Tct 0 +MICB UCSF GRCh37 6 31473641 31473641 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 6 22 0 ENST00000252229.6:c.318G>A p.Gln106= p.Q106= ENST00000252229 NM_005931.3 106 caG/caA 0 +MICU1 UCSF GRCh37 10 74183121 74183121 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 100 65 107 0 ENST00000361114.5:c.942C>T p.Arg314= p.R314= ENST00000361114 NM_001195518.1 314 cgC/cgT 0 +MLH1 UCSF GRCh37 3 37090054 37090054 + missense_variant Missense_Mutation SNP C C T snp132_rs63750610 P01_Rec somatic WXS Sanger Illumina HiSeq 5 18 44 0 ENST00000231790.2:c.1943C>T p.Pro648Leu p.P648L ENST00000231790 NM_000249.3 648 cCc/cTc 0 +MLH3 UCSF GRCh37 14 75513566 75513566 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 156 21 198 0 ENST00000355774.2:c.2793G>A p.Glu931= p.E931= ENST00000355774 NM_001040108.1 931 gaG/gaA 0 +MLL UCSF GRCh37 11 118352750 118352750 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 27 48 0 ENST00000534358.1:c.3955G>A p.Val1319Ile p.V1319I ENST00000534358 NM_005933.3 1319 Gtt/Att 0 +MLL UCSF GRCh37 11 118366480 118366480 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 40 16 75 0 ENST00000534358.1:c.5429A>G p.Glu1810Gly p.E1810G ENST00000534358 NM_005933.3 1810 gAg/gGg 0 +MLL2 UCSF GRCh37 12 49436538 49436538 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 44 67 0 ENST00000301067.7:c.5768G>A p.Arg1923Lys p.R1923K ENST00000301067 NM_003482.3 1923 aGg/aAg 0 +MLL2 UCSF GRCh37 12 49448494 49448494 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 12 28 0 ENST00000301067.7:c.217G>A p.Glu73Lys p.E73K ENST00000301067 NM_003482.3 73 Gag/Aag 0 +MLL2 UCSF GRCh37 12 49440104 49440104 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 28 40 0 ENST00000301067.7:c.4522C>T p.Pro1508Ser p.P1508S ENST00000301067 NM_003482.3 1508 Cct/Tct 0 +MLL2 UCSF GRCh37 12 49433798 49433798 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 5 29 0 ENST00000301067.7:c.7755G>A p.Gly2585= p.G2585= ENST00000301067 NM_003482.3 2585 ggG/ggA 0 +MLL3 UCSF GRCh37 7 151874749 151874749 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 12 69 0 ENST00000262189.6:c.7789C>T p.Pro2597Ser p.P2597S ENST00000262189 NM_170606.2 2597 Cca/Tca 0 +MLL3 UCSF GRCh37 7 151874636 151874636 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 92 18 64 0 ENST00000262189.6:c.7902G>A p.Glu2634= p.E2634= ENST00000262189 NM_170606.2 2634 gaG/gaA 0 +MLL5 UCSF GRCh37 7 104745979 104745979 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 17 107 0 ENST00000311117.3:c.2290C>T p.Pro764Ser p.P764S ENST00000311117 NM_182931.2 764 Cct/Tct 0 +MLLT4 UCSF GRCh37 6 168352396 168352396 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 9 71 0 ENST00000392108.3:c.4341G>A p.Gln1447= p.Q1447= ENST00000392108 NM_001040000.2 1447 caG/caA 0 +MLPH UCSF GRCh37 2 238419669 238419669 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 143 17 94 0 ENST00000264605.3:c.370C>T p.His124Tyr p.H124Y ENST00000264605 NM_024101.6 124 Cat/Tat 0 +MMP9 UCSF GRCh37 20 44640922 44640922 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 10 27 0 ENST00000372330.3:c.1144G>A p.Asp382Asn p.D382N ENST00000372330 NM_004994.2 382 Gac/Aac 0 +MOAP1 UCSF GRCh37 14 93650341 93650341 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 20 130 0 ENST00000556883.1:c.247C>T p.Pro83Ser p.P83S ENST00000556883 83 Ccg/Tcg 0 +MOAP1 UCSF GRCh37 14 93649577 93649577 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 29 66 0 ENST00000556883.1:c.1011G>A p.Glu337= p.E337= ENST00000556883 337 gaG/gaA 0 +MOB3A UCSF GRCh37 19 2078282 2078282 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 9 10 0 ENST00000357066.3:c.278G>A p.Gly93Glu p.G93E ENST00000357066 NM_130807.2 93 gGg/gAg 0 +MORC4 UCSF GRCh37 X 106229341 106229341 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 30 56 0 ENST00000355610.4:c.398G>A p.Gly133Glu p.G133E ENST00000355610 NM_001085354.2 133 gGa/gAa 0 +MOSPD1 UCSF GRCh37 X 134033430 134033430 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 8 44 0 ENST00000370783.3:c.34G>A p.Glu12Lys p.E12K ENST00000370783 NM_019556.1 12 Gaa/Aaa 0 +MOV10L1 UCSF GRCh37 22 50588095 50588095 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 3 15 0 ENST00000262794.5:c.2679G>A p.Glu893= p.E893= ENST00000262794 NM_018995.2 893 gaG/gaA 0 +MRPL10 UCSF GRCh37 17 45904022 45904022 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 3 37 0 ENST00000290208.7:c.543G>A p.Val181= p.V181= ENST00000290208 181 gtG/gtA 0 +MRPS17 UCSF GRCh37 7 56022783 56022783 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 49 76 0 ENST00000285298.4:c.305G>A p.Gly102Glu p.G102E ENST00000285298 NM_015969.2 102 gGa/gAa 0 +MRVI1 UCSF GRCh37 11 10602125 10602125 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 113 21 92 0 ENST00000423302.2:c.2372G>A p.Gly791Asp p.G791D ENST00000423302 NM_130385.3 791 gGt/gAt 0 +MSLN UCSF GRCh37 16 816698 816698 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 22 0 ENST00000382862.3:c.1285G>A p.Gly429Arg p.G429R ENST00000382862 NM_013404.4 429 Gga/Aga 0 +MSN UCSF GRCh37 X 64949352 64949352 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 12 40 0 ENST00000360270.5:c.245C>T p.Ala82Val p.A82V ENST00000360270 NM_002444.2 82 gCc/gTc 0 +MST1 UCSF GRCh37 3 49725201 49725201 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 5 15 31 0 ENST00000449682.2:c.224G>A p.Gly75Glu p.G75E ENST00000449682 NM_020998.3 75 gGg/gAg 0 +MST1 UCSF GRCh37 3 49723144 49723144 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.040,snp132_rs9713630 P01_Rec Untested WXS Illumina HiSeq 17 7 25 1 ENST00000449682.2:c.1272G>A p.Pro424= p.P424= ENST00000449682 NM_020998.3 424 ccG/ccA 0 +MSX1 UCSF GRCh37 4 4864447 4864447 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 27 37 0 ENST00000382723.4:c.489C>T p.Ala163= p.A163= ENST00000382723 NM_002448.3 163 gcC/gcT 0 +MTIF3 UCSF GRCh37 13 28014446 28014446 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 87 13 108 0 ENST00000381116.1:c.140C>T p.Ser47Phe p.S47F ENST00000381116 47 tCc/tTc 0 +MTMR14 UCSF GRCh37 3 9712828 9712828 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 23 54 0 ENST00000296003.4:c.651G>A p.Glu217= p.E217= ENST00000296003 NM_001077525.2 217 gaG/gaA 0 +MTNR1B UCSF GRCh37 11 92715267 92715267 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 39 72 0 ENST00000257068.2:c.878G>A p.Ser293Asn p.S293N ENST00000257068 NM_005959.3 293 aGc/aAc 0 +MTOR UCSF GRCh37 1 11184573 11184573 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 36 26 41 0 ENST00000361445.4:c.6644C>T p.Ser2215Phe p.S2215F ENST00000361445 NM_004958.3 2215 tCt/tTt 0 +MUC12 UCSF GRCh37 7 100646542 100646542 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 213 47 168 0 ENST00000536621.1:c.12698G>A p.Ser4233Asn p.S4233N ENST00000536621 NM_001164462.1 4233 aGc/aAc 0 +MUC17 UCSF GRCh37 7 100676996 100676996 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 192 25 155 0 ENST00000306151.4:c.2299C>T p.Leu767Phe p.L767F ENST00000306151 NM_001040105.1 767 Ctt/Ttt 0 +MUC17 UCSF GRCh37 7 100684346 100684346 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 129 75 155 0 ENST00000306151.4:c.9649C>T p.Pro3217Ser p.P3217S ENST00000306151 NM_001040105.1 3217 Cct/Tct 0 +MUC2 UCSF GRCh37 11 1092260 1092260 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 7 52 0 ENST00000441003.2:c.4079C>T p.Ser1360Phe p.S1360F ENST00000441003 NM_002457.2 1360 tCt/tTt 0 +MUC21 UCSF GRCh37 6 30954428 30954428 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 153 17 71 0 ENST00000376296.3:c.476C>T p.Ser159Phe p.S159F ENST00000376296 NM_001010909.2 159 tCc/tTc 0 +MUC21 UCSF GRCh37 6 30954650 30954650 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 139 22 83 0 ENST00000376296.3:c.698C>T p.Thr233Ile p.T233I ENST00000376296 NM_001010909.2 233 aCc/aTc 0 +MUC4 UCSF GRCh37 3 195513478 195513478 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 206 88 326 0 ENST00000463781.3:c.4973C>T p.Ser1658Phe p.S1658F ENST00000463781 NM_018406.6 1658 tCc/tTc 0 +MYBL1 UCSF GRCh37 8 67484738 67484739 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 0 ENST00000522677.3:c.1707dup p.Tyr570IlefsTer5 p.Y570Ifs*5 ENST00000522677 NM_001080416.2 569 aaa/aaAa 0 +MYBL2 UCSF GRCh37 20 42338616 42338616 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 107 25 95 0 ENST00000217026.4:c.1519G>A p.Asp507Asn p.D507N ENST00000217026 NM_002466.3 507 Gat/Aat 0 +MYBPHL UCSF GRCh37 1 109839724 109839724 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 20 60 0 ENST00000357155.1:c.518G>A p.Gly173Glu p.G173E ENST00000357155 NM_001265613.1 173 gGg/gAg 0 +MYCBP2 UCSF GRCh37 13 77642966 77642966 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 12 65 0 ENST00000544440.2:c.11791G>A p.Val3931Met p.V3931M ENST00000544440 3931 Gtg/Atg 0 +MYH10 UCSF GRCh37 17 8416890 8416890 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 34 38 0 ENST00000360416.3:c.2711G>A p.Gly904Glu p.G904E ENST00000360416 NM_001256012.1 904 gGa/gAa 0 +MYH11 UCSF GRCh37 16 15835500 15835500 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 65 38 62 0 ENST00000396324.3:c.2700G>A p.Gln900= p.Q900= ENST00000396324 NM_001040114.1 900 caG/caA 0 +MYH13 UCSF GRCh37 17 10206579 10206579 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 84 46 69 0 ENST00000418404.3:c.5601G>A p.Arg1867= p.R1867= ENST00000418404 1867 agG/agA 0 +MYH13 UCSF GRCh37 17 10267644 10267644 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 15 120 0 ENST00000418404.3:c.204G>A p.Arg68= p.R68= ENST00000418404 68 cgG/cgA 0 +MYH4 UCSF GRCh37 17 10363607 10363607 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 55 46 64 0 ENST00000255381.2:c.1179G>A p.Leu393= p.L393= ENST00000255381 NM_017533.2 393 ctG/ctA 0 +MYH6 UCSF GRCh37 14 23862195 23862195 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 11 32 0 ENST00000405093.3:c.3177C>T p.Gly1059= p.G1059= ENST00000405093 NM_002471.3 1059 ggC/ggT 0 +MYH7 UCSF GRCh37 14 23884352 23884352 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 29 41 0 ENST00000355349.3:c.5411C>T p.Ala1804Val p.A1804V ENST00000355349 NM_000257.2 1804 gCc/gTc 0 +MYH8 UCSF GRCh37 17 10305018 10305018 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 115 74 146 0 ENST00000403437.2:c.2773G>A p.Val925Met p.V925M ENST00000403437 NM_002472.2 925 Gtg/Atg 0 +MYL3 UCSF GRCh37 3 46904778 46904778 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 4 46 0 ENST00000395869.1:c.103G>A p.Val35Ile p.V35I ENST00000395869 35 Gtc/Atc 0 +MYLK UCSF GRCh37 3 123419528 123419528 + synonymous_variant Silent SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 26 10 64 1 ENST00000360304.3:c.2787G>A p.Leu929= p.L929= ENST00000360304 NM_053025.3 929 ctG/ctA 0 +MYO10 UCSF GRCh37 5 16701512 16701512 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 16 24 0 ENST00000513610.1:c.2992G>A p.Glu998Lys p.E998K ENST00000513610 NM_012334.2 998 Gaa/Aaa 0 +MYO10 UCSF GRCh37 5 16701948 16701948 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 12 54 0 ENST00000513610.1:c.2557-1G>A p.X853_splice ENST00000513610 NM_012334.2 0 +MYO15A UCSF GRCh37 17 18047868 18047868 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 17 0 ENST00000205890.5:c.6235G>A p.Ala2079Thr p.A2079T ENST00000205890 NM_016239.3 2079 Gcc/Acc 0 +MYO16 UCSF GRCh37 13 109365014 109365014 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 8 43 0 ENST00000356711.2:c.232C>T p.Arg78Trp p.R78W ENST00000356711 NM_015011.1 78 Cgg/Tgg 0 +MYO1E UCSF GRCh37 15 59445946 59445946 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 36 39 0 ENST00000288235.4:c.2923C>T p.Pro975Ser p.P975S ENST00000288235 NM_004998.3 975 Ccc/Tcc 0 +MYO3A UCSF GRCh37 10 26305789 26305789 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 35 88 0 ENST00000265944.5:c.549C>T p.Asn183= p.N183= ENST00000265944 NM_017433.4 183 aaC/aaT 0 +MYO3B UCSF GRCh37 2 171262121 171262121 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 13 55 0 ENST00000408978.4:c.2498G>A p.Gly833Asp p.G833D ENST00000408978 NM_138995.4 833 gGc/gAc 0 +MYO3B UCSF GRCh37 2 171238526 171238526 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 94 15 97 0 ENST00000408978.4:c.972G>A p.Arg324= p.R324= ENST00000408978 NM_138995.4 324 agG/agA 0 +MYO7B UCSF GRCh37 2 128393887 128393887 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 10 14 0 ENST00000428314.1:c.6033C>T p.Phe2011= p.F2011= ENST00000428314 NM_001080527.1 2011 ttC/ttT 0 +MYOCD UCSF GRCh37 17 12666467 12666467 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 41 42 77 0 ENST00000425538.1:c.2467A>G p.Thr823Ala p.T823A ENST00000425538 NM_001146312.1 823 Act/Gct 0 +MYOCD UCSF GRCh37 17 12620673 12620673 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 22 58 0 ENST00000425538.1:c.188C>T p.Ser63Phe p.S63F ENST00000425538 NM_001146312.1 63 tCc/tTc 0 +MYOF UCSF GRCh37 10 95111245 95111245 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 21 73 0 ENST00000359263.4:c.3747C>T p.Leu1249= p.L1249= ENST00000359263 NM_013451.3 1249 ctC/ctT 0 +MYOM1 UCSF GRCh37 18 3151764 3151764 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 60 87 0 ENST00000356443.4:c.1771G>A p.Gly591Arg p.G591R ENST00000356443 NM_019856.1 591 Gga/Aga 0 +MYOM1 UCSF GRCh37 18 3173967 3173967 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 20 76 0 ENST00000356443.4:c.1143C>T p.Phe381= p.F381= ENST00000356443 NM_019856.1 381 ttC/ttT 0 +MYPN UCSF GRCh37 10 69959267 69959267 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 17 59 0 ENST00000358913.5:c.3428C>T p.Thr1143Ile p.T1143I ENST00000358913 NM_032578.3 1143 aCc/aTc 0 +MYPN UCSF GRCh37 10 69881321 69881321 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 21 47 0 ENST00000358913.5:c.126C>T p.Cys42= p.C42= ENST00000358913 NM_032578.3 42 tgC/tgT 0 +MYRIP UCSF GRCh37 3 40208666 40208666 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 4 26 24 0 ENST00000302541.6:c.665C>T p.Ala222Val p.A222V ENST00000302541 NM_015460.2 222 gCc/gTc 0 +NAALADL1 UCSF GRCh37 11 64821987 64821987 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 9 19 0 ENST00000358658.3:c.827C>T p.Ser276Phe p.S276F ENST00000358658 NM_005468.2 276 tCc/tTc 0 +NACA UCSF GRCh37 12 57114689 57114689 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 36 77 0 ENST00000550952.1:c.625G>A p.Val209Ile p.V209I ENST00000550952 209 Gtc/Atc 0 +NAE1 UCSF GRCh37 16 66850916 66850916 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 17 94 0 ENST00000290810.3:c.700C>T p.Pro234Ser p.P234S ENST00000290810 234 Cct/Tct 0 +NAIF1 UCSF GRCh37 9 130829281 130829281 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 10 38 0 ENST00000373078.4:c.100C>T p.His34Tyr p.H34Y ENST00000373078 NM_197956.3 34 Cac/Tac 0 +NALCN UCSF GRCh37 13 101721137 101721137 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 12 51 0 ENST00000251127.6:c.4240G>A p.Ala1414Thr p.A1414T ENST00000251127 NM_052867.2 1414 Gca/Aca 0 +NAV1 UCSF GRCh37 1 201682021 201682021 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 20 43 0 ENST00000367296.4:c.834C>T p.Ser278= p.S278= ENST00000367296 NM_020443.4 278 agC/agT 0 +NAV3 UCSF GRCh37 12 78401021 78401021 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 11 65 0 ENST00000536525.2:c.1703C>T p.Pro568Leu p.P568L ENST00000536525 NM_014903.4 568 cCt/cTt 0 +NBEAL2 UCSF GRCh37 3 47043734 47043734 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 7 9 30 0 ENST00000450053.3:c.5107G>A p.Ala1703Thr p.A1703T ENST00000450053 NM_015175.2 1703 Gct/Act 0 +NBPF3 UCSF GRCh37 1 21806654 21806654 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 97 46 107 0 ENST00000318249.5:c.1319C>T p.Pro440Leu p.P440L ENST00000318249 NM_032264.4 440 cCc/cTc 0 +NBPF3 UCSF GRCh37 1 21805842 21805842 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 142 22 131 0 ENST00000318249.5:c.1157G>A p.Arg386Lys p.R386K ENST00000318249 NM_032264.4 386 aGa/aAa 0 +NCAPG UCSF GRCh37 4 17844947 17844947 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 33 101 0 ENST00000251496.2:c.2947G>A p.Glu983Lys p.E983K ENST00000251496 NM_022346.4 983 Gaa/Aaa 0 +NCKAP1L UCSF GRCh37 12 54917237 54917237 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 97 21 107 0 ENST00000293373.6:c.1938G>A p.Lys646= p.K646= ENST00000293373 NM_005337.4 646 aaG/aaA 0 +NCKAP5 UCSF GRCh37 2 133540233 133540233 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 11 31 0 ENST00000409261.1:c.4151G>A p.Gly1384Glu p.G1384E ENST00000409261 NM_207363.2 1384 gGa/gAa 0 +NCOA3 UCSF GRCh37 20 46279918 46279918 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.00197 P01_Rec Untested WXS Illumina HiSeq 35 7 48 0 ENST00000371998.3:c.3844C>T p.Pro1282Ser p.P1282S ENST00000371998 1282 Cca/Tca 0 +NCOR1 UCSF GRCh37 17 16022800 16022800 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 93 33 105 0 ENST00000268712.3:c.1853-1G>A p.X618_splice ENST00000268712 NM_006311.3 0 +NCSTN UCSF GRCh37 1 160321500 160321500 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 131 21 116 0 ENST00000294785.5:c.748C>T p.Pro250Ser p.P250S ENST00000294785 NM_015331.2 250 Ccc/Tcc 0 +NDST1 UCSF GRCh37 5 149907410 149907410 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 11 14 0 ENST00000261797.6:c.558C>T p.Pro186= p.P186= ENST00000261797 NM_001543.4 186 ccC/ccT 0 +NDST3 UCSF GRCh37 4 119059216 119059216 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 14 59 0 ENST00000296499.5:c.1232G>A p.Gly411Asp p.G411D ENST00000296499 NM_004784.2 411 gGc/gAc 0 +NDUFS1 UCSF GRCh37 2 207014633 207014633 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 26 63 0 ENST00000455934.2:c.212G>A p.Gly71Asp p.G71D ENST00000455934 NM_001199984.1 71 gGc/gAc 0 +NEB UCSF GRCh37 2 152468732 152468732 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 113 20 119 0 ENST00000397345.3:c.11773C>T p.Leu3925= p.L3925= ENST00000397345 NM_001164508.1 3925 Cta/Tta 0 +NECAB1 UCSF GRCh37 8 91937778 91937778 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 35 73 0 ENST00000417640.2:c.510G>A p.Lys170= p.K170= ENST00000417640 NM_022351.4 170 aaG/aaA 0 +NEDD4 UCSF GRCh37 15 56139232 56139232 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 12 79 0 ENST00000338963.2:c.2584G>A p.Ala862Thr p.A862T ENST00000338963 NM_198400.2 862 Gca/Aca 0 +NEDD9 UCSF GRCh37 6 11191145 11191145 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 8 39 0 ENST00000379446.5:c.957C>T p.Val319= p.V319= ENST00000379446 NM_001271033.1 319 gtC/gtT 0 +NEK3 UCSF GRCh37 13 52715162 52715162 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 14 50 0 ENST00000400357.2:c.876+2889C>T *292* ENST00000400357 0 +NEK9 UCSF GRCh37 14 75558142 75558142 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 23 0 ENST00000238616.5:c.2273G>A p.Gly758Asp p.G758D ENST00000238616 NM_033116.4 758 gGc/gAc 0 +NELF UCSF GRCh37 9 140346820 140346820 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 104 22 47 0 ENST00000371475.3:c.1233C>T p.Cys411= p.C411= ENST00000371475 NM_001130969.1 411 tgC/tgT 0 +NET1 UCSF GRCh37 10 5494459 5494459 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 10 28 0 ENST00000355029.4:c.502C>T p.Leu168Phe p.L168F ENST00000355029 NM_001047160.2 168 Ctc/Ttc 0 +NEU1 UCSF GRCh37 6 31827515 31827515 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 14 64 0 ENST00000375631.4:c.1229G>A p.Ser410Asn p.S410N ENST00000375631 NM_000434.3 410 aGt/aAt 0 +NEURL2 UCSF GRCh37 20 44518890 44518890 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 9 11 0 ENST00000372518.4:c.741C>T p.Gly247= p.G247= ENST00000372518 NM_001278535.1 247 ggC/ggT 0 +NEUROG3 UCSF GRCh37 10 71332566 71332566 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 6 10 0 ENST00000242462.4:c.234C>T p.Ser78= p.S78= ENST00000242462 NM_020999.3 78 agC/agT 0 +NF1 UCSF GRCh37 17 29553505 29553505 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 34 22 47 0 ENST00000358273.4:c.2054C>T p.Thr685Ile p.T685I ENST00000358273 NM_001042492.2 685 aCc/aTc 0 +NFASC UCSF GRCh37 1 204970336 204970336 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 5 29 0 ENST00000339876.6:c.3058C>T p.Pro1020Ser p.P1020S ENST00000339876 NM_001005388.2 1020 Ccc/Tcc 0 +NFATC3 UCSF GRCh37 16 68224758 68224758 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 47 74 0 ENST00000346183.3:c.2186C>T p.Pro729Leu p.P729L ENST00000346183 NM_173165.2 729 cCt/cTt 0 +NFKBID UCSF GRCh37 19 36387847 36387847 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 11 30 0 ENST00000396901.1:c.120G>A p.Gln40= p.Q40= ENST00000396901 NM_139239.1 40 caG/caA 0 +NFKBIE UCSF GRCh37 6 44230365 44230365 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 9 22 0 ENST00000275015.5:c.817G>A p.Ala273Thr p.A273T ENST00000275015 NM_004556.2 273 Gcg/Acg 0 +NHS UCSF GRCh37 X 17744999 17744999 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 58 62 0 ENST00000380060.3:c.2710C>T p.Pro904Ser p.P904S ENST00000380060 NM_198270.2 904 Cct/Tct 0 +NHSL1 UCSF GRCh37 6 138752697 138752697 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 9 17 0 ENST00000427025.2:c.2797G>A p.Ala933Thr p.A933T ENST00000427025 NM_020464.1 933 Gct/Act 0 +NHSL1 UCSF GRCh37 6 138753049 138753049 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 18 24 0 ENST00000427025.2:c.2445G>A p.Gly815= p.G815= ENST00000427025 NM_020464.1 815 ggG/ggA 0 +NHSL1 UCSF GRCh37 6 138753691 138753691 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 107 14 88 0 ENST00000427025.2:c.1803G>A p.Gly601= p.G601= ENST00000427025 NM_020464.1 601 ggG/ggA 0 +NID1 UCSF GRCh37 1 236180524 236180524 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 10 74 0 ENST00000264187.6:c.2178C>T p.Ile726= p.I726= ENST00000264187 NM_002508.2 726 atC/atT 0 +NKTR UCSF GRCh37 3 42662979 42662979 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 7 70 0 ENST00000232978.8:c.345G>A p.Gly115= p.G115= ENST00000232978 NM_005385.3 115 ggG/ggA 0 +NLN UCSF GRCh37 5 65105515 65105515 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 29 85 0 ENST00000380985.5:c.1701G>A p.Arg567= p.R567= ENST00000380985 NM_020726.4 567 agG/agA 0 +NLRC3 UCSF GRCh37 16 3604266 3604266 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 4 16 0 ENST00000448023.2:c.2385C>T p.Ser795= p.S795= ENST00000448023 795 tcC/tcT 0 +NLRP14 UCSF GRCh37 11 7083698 7083698 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 69 44 119 0 ENST00000299481.4:c.2939C>T p.Ala980Val p.A980V ENST00000299481 NM_176822.3 980 gCt/gTt 0 +NLRP4 UCSF GRCh37 19 56382267 56382267 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 7 46 0 ENST00000301295.6:c.2429G>A p.Arg810His p.R810H ENST00000301295 NM_134444.4 810 cGc/cAc 0 +NMBR UCSF GRCh37 6 142409531 142409531 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 17 15 0 ENST00000258042.1:c.265G>A p.Asp89Asn p.D89N ENST00000258042 NM_002511.2 89 Gac/Aac 0 +NME1-NME2 UCSF GRCh37 17 49248858 49248858 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 39 59 0 ENST00000393193.2:c.697C>T p.His233Tyr p.H233Y ENST00000393193 233 Cat/Tat 0 +NME1-NME2 UCSF GRCh37 17 49248924 49248924 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 18 78 0 ENST00000393193.2:c.763G>A p.Val255Ile p.V255I ENST00000393193 255 Gtt/Att 0 +NOB1 UCSF GRCh37 16 69783509 69783509 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 11 80 0 ENST00000268802.5:c.352C>T p.His118Tyr p.H118Y ENST00000268802 NM_014062.2 118 Cac/Tac 0 +NOL8 UCSF GRCh37 9 95077331 95077331 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 22 66 0 ENST00000545558.1:c.1576C>T p.Pro526Ser p.P526S ENST00000545558 526 Ccc/Tcc 0 +NOL9 UCSF GRCh37 1 6592067 6592067 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 12 80 0 ENST00000377705.5:c.1608C>T p.Pro536= p.P536= ENST00000377705 NM_024654.4 536 ccC/ccT 0 +NOMO2 UCSF GRCh37 16 18555043 18555043 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 15 141 0 ENST00000381474.3:c.631C>T p.Pro211Ser p.P211S ENST00000381474 NM_001004060.1 211 Ccc/Tcc 0 +NOS2 UCSF GRCh37 17 26107878 26107878 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 10 20 0 ENST00000313735.6:c.919C>T p.Leu307= p.L307= ENST00000313735 NM_000625.4 307 Ctg/Ttg 0 +NOTCH2 UCSF GRCh37 1 120478152 120478152 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 48 90 0 ENST00000256646.2:c.3598G>A p.Gly1200Ser p.G1200S ENST00000256646 NM_024408.3 1200 Ggc/Agc 0 +NPAS3 UCSF GRCh37 14 34269087 34269087 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 4 9 0 ENST00000356141.4:c.1574G>A p.Ser525Asn p.S525N ENST00000356141 525 aGc/aAc 0 +NPFF UCSF GRCh37 12 53900629 53900629 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 38 98 0 ENST00000267017.3:c.273C>T p.Pro91= p.P91= ENST00000267017 NM_003717.2 91 ccC/ccT 0 +NPHP1 UCSF GRCh37 2 110922642 110922642 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 75 12 84 0 ENST00000316534.4:c.715G>A p.Glu239Lys p.E239K ENST00000316534 239 Gaa/Aaa 0 +NPRL2 UCSF GRCh37 3 50386307 50386307 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 11 28 48 0 ENST00000232501.3:c.583C>T p.Gln195Ter p.Q195* ENST00000232501 NM_006545.4 195 Caa/Taa 0 +NR1H3 UCSF GRCh37 11 47282796 47282796 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 7 16 0 ENST00000467728.1:c.504C>T p.Val168= p.V168= ENST00000467728 168 gtC/gtT 0 +NRIP1 UCSF GRCh37 21 16337740 16337740 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 97 68 143 0 ENST00000400202.1:c.2774G>A p.Ser925Asn p.S925N ENST00000400202 925 aGt/aAt 0 +NRIP1 UCSF GRCh37 21 16340169 16340169 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 16 107 0 ENST00000400202.1:c.345G>A p.Leu115= p.L115= ENST00000400202 115 ttG/ttA 0 +NRIP2 UCSF GRCh37 12 2944109 2944109 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 6 16 0 ENST00000337508.4:c.41C>T p.Ser14Phe p.S14F ENST00000337508 NM_031474.2 14 tCc/tTc 0 +NRIP2 UCSF GRCh37 12 2937137 2937137 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 6 24 0 ENST00000337508.4:c.655C>T p.Leu219= p.L219= ENST00000337508 NM_031474.2 219 Cta/Tta 0 +NRP1 UCSF GRCh37 10 33486635 33486635 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 6 48 0 ENST00000265371.4:c.1867G>A p.Gly623Ser p.G623S ENST00000265371 623 Ggc/Agc 0 +NRXN1 UCSF GRCh37 2 50850507 50850507 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 55 141 0 ENST00000404971.1:c.1178G>A p.Gly393Glu p.G393E ENST00000404971 NM_001135659.1 393 gGa/gAa 0 +NSUN6 UCSF GRCh37 10 18903531 18903531 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 43 0 ENST00000377304.4:c.433G>A p.Gly145Arg p.G145R ENST00000377304 NM_182543.2 145 Gga/Aga 0 +NT5C2 UCSF GRCh37 10 104849440 104849440 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 14 20 0 ENST00000343289.5:c.1675G>A p.Glu559Lys p.E559K ENST00000343289 NM_012229.4 559 Gag/Aag 0 +NTNG1 UCSF GRCh37 1 107979300 107979300 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 56 102 0 ENST00000370068.1:c.1269C>T p.Asn423= p.N423= ENST00000370068 423 aaC/aaT 0 +NUDT21 UCSF GRCh37 16 56485037 56485037 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 5 37 0 ENST00000300291.5:c.78G>A p.Gln26= p.Q26= ENST00000300291 NM_007006.2 26 caG/caA 0 +NUFIP1 UCSF GRCh37 13 45563287 45563287 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 14 16 0 ENST00000379161.4:c.285C>T p.Ala95= p.A95= ENST00000379161 NM_012345.2 95 gcC/gcT 0 +NUP133 UCSF GRCh37 1 229611477 229611477 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 9 62 0 ENST00000261396.3:c.1759G>A p.Ala587Thr p.A587T ENST00000261396 NM_018230.2 587 Gca/Aca 0 +NUP153 UCSF GRCh37 6 17632906 17632906 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 132 16 78 0 ENST00000262077.2:c.2634G>A p.Lys878= p.K878= ENST00000262077 NM_001278210.1 878 aaG/aaA 0 +NUP210 UCSF GRCh37 3 13363194 13363194 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 50 72 0 ENST00000254508.5:c.5057C>T p.Pro1686Leu p.P1686L ENST00000254508 NM_024923.3 1686 cCc/cTc 0 +NUP214 UCSF GRCh37 9 134074253 134074253 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 101 24 49 0 ENST00000359428.5:c.5372C>T p.Pro1791Leu p.P1791L ENST00000359428 NM_005085.3 1791 cCc/cTc 0 +NUP214 UCSF GRCh37 9 134038400 134038400 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 96 32 63 0 ENST00000359428.5:c.2563G>A p.Glu855Lys p.E855K ENST00000359428 NM_005085.3 855 Gag/Aag 0 +NUP214 UCSF GRCh37 9 134074061 134074061 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 9 37 0 ENST00000359428.5:c.5180G>A p.Gly1727Glu p.G1727E ENST00000359428 NM_005085.3 1727 gGg/gAg 0 +NUP98 UCSF GRCh37 11 3697537 3697537 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 4 14 25 0 ENST00000324932.7:c.5255C>T p.Ser1752Phe p.S1752F ENST00000324932 NM_139132.3 1752 tCc/tTc 0 +NUP98 UCSF GRCh37 11 3733811 3733811 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 40 68 0 ENST00000324932.7:c.2725C>T p.Pro909Ser p.P909S ENST00000324932 NM_139132.3 909 Cct/Tct 0 +NUPL1 UCSF GRCh37 13 25905536 25905536 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 28 43 0 ENST00000381736.3:c.1275G>A p.Leu425= p.L425= ENST00000381736 NM_014089.3 425 ttG/ttA 0 +NVL UCSF GRCh37 1 224468833 224468833 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 28 89 0 ENST00000281701.6:c.1954C>T p.Leu652= p.L652= ENST00000281701 NM_002533.3 652 Cta/Tta 0 +NYNRIN UCSF GRCh37 14 24878470 24878470 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 53 17 46 0 ENST00000382554.3:c.1470G>A p.Gln490= p.Q490= ENST00000382554 NM_025081.2 490 caG/caA 0 +OBSCN UCSF GRCh37 1 228451969 228451969 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 11 63 0 ENST00000570156.2:c.5290G>A p.Val1764Met p.V1764M ENST00000570156 NM_001271223.2 1764 Gtg/Atg 0 +OBSCN UCSF GRCh37 1 228509188 228509188 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 14 21 0 ENST00000570156.2:c.17517C>T p.Ala5839= p.A5839= ENST00000570156 NM_001271223.2 5839 gcC/gcT 0 +ODF2 UCSF GRCh37 9 131261283 131261283 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 29 40 0 ENST00000434106.3:c.2179G>A p.Glu727Lys p.E727K ENST00000434106 NM_153433.1 727 Gaa/Aaa 0 +OGDHL UCSF GRCh37 10 50952079 50952079 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 10 10 0 ENST00000374103.4:c.1822G>A p.Ala608Thr p.A608T ENST00000374103 NM_018245.2 608 Gcc/Acc 0 +OGFRL1 UCSF GRCh37 6 72006265 72006265 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 14 63 0 ENST00000370435.4:c.546+1G>A p.X182_splice ENST00000370435 NM_024576.3 0 +OLFML2A UCSF GRCh37 9 127563934 127563934 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 9 27 0 ENST00000373580.3:c.911C>T p.Ala304Val p.A304V ENST00000373580 NM_182487.2 304 gCg/gTg 0 +OLFML2A UCSF GRCh37 9 127570103 127570103 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 8 21 0 ENST00000373580.3:c.1212C>T p.Pro404= p.P404= ENST00000373580 NM_182487.2 404 ccC/ccT 0 +OLFML3 UCSF GRCh37 1 114523942 114523942 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 23 38 0 ENST00000320334.4:c.772C>T p.Pro258Ser p.P258S ENST00000320334 NM_020190.2 258 Cca/Tca 0 +OPCML UCSF GRCh37 11 132306126 132306126 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 45 60 0 ENST00000331898.7:c.791C>T p.Ala264Val p.A264V ENST00000331898 NM_002545.3 264 gCc/gTc 0 +OPCML UCSF GRCh37 11 132527148 132527148 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 18 32 0 ENST00000331898.7:c.234G>A p.Gly78= p.G78= ENST00000331898 NM_002545.3 78 ggG/ggA 0 +OR10A3 UCSF GRCh37 11 7960335 7960335 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 37 63 0 ENST00000360759.3:c.733C>T p.Leu245Phe p.L245F ENST00000360759 NM_001003745.1 245 Ctc/Ttc 0 +OR10R2 UCSF GRCh37 1 158450020 158450020 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 151 34 119 0 ENST00000368152.1:c.353C>T p.Ala118Val p.A118V ENST00000368152 NM_001004472.1 118 gCt/gTt 0 +OR10S1 UCSF GRCh37 11 123848113 123848113 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 8 17 0 ENST00000531945.1:c.286G>A p.Ala96Thr p.A96T ENST00000531945 NM_001004474.1 96 Gca/Aca 0 +OR10S1 UCSF GRCh37 11 123848289 123848289 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 8 49 0 ENST00000531945.1:c.110C>T p.Ser37Phe p.S37F ENST00000531945 NM_001004474.1 37 tCt/tTt 0 +OR14J1 UCSF GRCh37 6 29274902 29274902 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 95 34 67 0 ENST00000377160.2:c.436G>A p.Val146Met p.V146M ENST00000377160 NM_030946.1 146 Gtg/Atg 0 +OR1A2 UCSF GRCh37 17 3101003 3101003 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 59 100 0 ENST00000381951.1:c.191C>T p.Ala64Val p.A64V ENST00000381951 NM_012352.1 64 gCc/gTc 0 +OR1C1 UCSF GRCh37 1 247921698 247921698 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 9 51 0 ENST00000408896.2:c.11G>A p.Arg4Lys p.R4K ENST00000408896 NM_012353.2 4 aGa/aAa 0 +OR2B3 UCSF GRCh37 6 29054960 29054960 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 21 54 0 ENST00000377173.2:c.66G>A p.Trp22Ter p.W22* ENST00000377173 NM_001005226.2 22 tgG/tgA 0 +OR2G2 UCSF GRCh37 1 247752365 247752365 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 27 51 0 ENST00000320065.1:c.704C>T p.Thr235Ile p.T235I ENST00000320065 NM_001001915.1 235 aCc/aTc 0 +OR3A2 UCSF GRCh37 17 3181566 3181566 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 20 50 0 ENST00000408891.2:c.664C>T p.Leu222Phe p.L222F ENST00000408891 NM_002551.3 222 Ctc/Ttc 0 +OR51B2 UCSF GRCh37 11 5345160 5345160 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 17 103 0 ENST00000328813.2:c.368C>T p.Ala123Val p.A123V ENST00000328813 NM_033180.4 123 gCc/gTc 0 +OR52B2 UCSF GRCh37 11 6190897 6190897 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 20 27 0 ENST00000530810.1:c.660C>T p.Tyr220= p.Y220= ENST00000530810 NM_001004052.1 220 taC/taT 0 +OR52W1 UCSF GRCh37 11 6220526 6220526 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 12 73 0 ENST00000311352.2:c.73C>T p.Leu25= p.L25= ENST00000311352 NM_001005178.1 25 Cta/Tta 0 +OR5K4 UCSF GRCh37 3 98073030 98073030 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 72 130 0 ENST00000354924.2:c.333C>T p.Asp111= p.D111= ENST00000354924 NM_001005517.1 111 gaC/gaT 0 +OR5L2 UCSF GRCh37 11 55595315 55595315 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 35 83 0 ENST00000378397.1:c.621G>A p.Glu207= p.E207= ENST00000378397 NM_001004739.1 207 gaG/gaA 0 +OR6C3 UCSF GRCh37 12 55725859 55725859 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 66 129 0 ENST00000379667.1:c.375G>A p.Lys125= p.K125= ENST00000379667 NM_054104.1 125 aaG/aaA 0 +OR7C1 UCSF GRCh37 19 14910638 14910638 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P01_Rec Untested WXS Illumina HiSeq 10 0 ENST00000248073.2:c.311delT p.Phe104SerfsTer12 p.F104Sfs*12 ENST00000248073 NM_198944.1 104 tTc/tc 0 +OR8G1 UCSF GRCh37 11 124121243 124121243 + intron_variant Intron SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 100 14 95 0 ENST00000341493.2:c.776+45C>T *259* ENST00000341493 NM_001002905.1 0 +OSBPL6 UCSF GRCh37 2 179170939 179170939 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 62 53 71 1 ENST00000392505.2:c.28C>T p.Pro10Ser p.P10S ENST00000392505 NM_001201480.1 10 Cct/Tct 0 +OSCAR UCSF GRCh37 19 54600250 54600250 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 3 24 0 ENST00000359649.4:c.284C>T p.Thr95Ile p.T95I ENST00000359649 NM_206818.1 95 aCt/aTt 0 +OSGEPL1 UCSF GRCh37 2 190618771 190618771 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 122 19 106 0 ENST00000264151.5:c.834C>T p.Ile278= p.I278= ENST00000264151 NM_022353.2 278 atC/atT 0 +OTOA UCSF GRCh37 16 21742223 21742223 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 9 50 0 ENST00000388958.3:c.2273G>A p.Gly758Glu p.G758E ENST00000388958 NM_144672.3 758 gGa/gAa 0 +OTUD4 UCSF GRCh37 4 146076591 146076591 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 6 32 129 0 ENST00000454497.2:c.650T>C p.Leu217Ser p.L217S ENST00000454497 NM_001102653.1 217 tTa/tCa 0 +OVOL2 UCSF GRCh37 20 18005411 18005411 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 10 38 0 ENST00000278780.6:c.697G>A p.Val233Met p.V233M ENST00000278780 NM_021220.2 233 Gtg/Atg 0 +OXCT2 UCSF GRCh37 1 40236219 40236219 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 18 56 0 ENST00000327582.5:c.709G>A p.Ala237Thr p.A237T ENST00000327582 NM_022120.1 237 Gct/Act 0 +OXNAD1 UCSF GRCh37 3 16343361 16343361 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 86 29 66 0 ENST00000285083.5:c.661G>A p.Glu221Lys p.E221K ENST00000285083 NM_138381.3 221 Gaa/Aaa 0 +P2RY14 UCSF GRCh37 3 150931103 150931103 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 55 155 0 ENST00000309170.3:c.1002C>T p.Ser334= p.S334= ENST00000309170 NM_014879.3 334 agC/agT 0 +P2RY4 UCSF GRCh37 X 69478678 69478678 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 6 15 0 ENST00000374519.2:c.797C>T p.Thr266Ile p.T266I ENST00000374519 NM_002565.3 266 aCc/aTc 0 +PABPC1 UCSF GRCh37 8 101717192 101717192 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 17 95 0 ENST00000318607.5:c.1780C>T p.Leu594Phe p.L594F ENST00000318607 NM_002568.3 594 Ctt/Ttt 0 +PABPC3 UCSF GRCh37 13 25672036 25672036 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 61 100 0 ENST00000281589.3:c.1700C>T p.Ala567Val p.A567V ENST00000281589 NM_030979.2 567 gCc/gTc 0 +PACSIN1 UCSF GRCh37 6 34496435 34496435 + missense_variant Missense_Mutation SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 62 14 42 2 ENST00000538621.1:c.237C>G p.Ser79Arg p.S79R ENST00000538621 NM_001199583.2 79 agC/agG 0 +PACSIN2 UCSF GRCh37 22 43289512 43289512 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 10 19 0 ENST00000263246.3:c.168G>A p.Ala56= p.A56= ENST00000263246 NM_001184970.1 56 gcG/gcA 0 +PADI3 UCSF GRCh37 1 17592190 17592190 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 24 35 0 ENST00000375460.3:c.383G>A p.Arg128Lys p.R128K ENST00000375460 NM_016233.2 128 aGg/aAg 0 +PADI4 UCSF GRCh37 1 17674544 17674544 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 4 17 0 ENST00000375448.4:c.1155+1G>A p.X385_splice ENST00000375448 NM_012387.2 0 +PADI6 UCSF GRCh37 1 17707598 17707598 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 7 18 0 ENST00000434762.2:n.542C>T *181* ENST00000434762 0 +PAIP1 UCSF GRCh37 5 43529973 43529973 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 26 109 0 ENST00000306846.3:c.1261G>A p.Glu421Lys p.E421K ENST00000306846 NM_006451.4 421 Gag/Aag 0 +PAN2 UCSF GRCh37 12 56726781 56726781 + missense_variant Missense_Mutation SNP A A T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 15 65 0 ENST00000425394.2:c.98T>A p.Leu33Gln p.L33Q ENST00000425394 NM_001127460.2 33 cTg/cAg 0 +PANK4 UCSF GRCh37 1 2452596 2452596 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 17 55 0 ENST00000378466.3:c.366G>A p.Ala122= p.A122= ENST00000378466 NM_018216.1 122 gcG/gcA 0 +PAPD7 UCSF GRCh37 5 6750520 6750520 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 8 36 0 ENST00000230859.6:c.1014C>T p.Pro338= p.P338= ENST00000230859 NM_001171805.1 338 ccC/ccT 0 +PAPOLA UCSF GRCh37 14 96986446 96986446 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 74 13 75 0 ENST00000216277.8:c.63C>T p.Gly21= p.G21= ENST00000216277 NM_032632.4 21 ggC/ggT 0 +PAPPA UCSF GRCh37 9 118950399 118950399 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 9 27 0 ENST00000328252.3:c.1382G>A p.Cys461Tyr p.C461Y ENST00000328252 NM_002581.3 461 tGc/tAc 0 +PAQR3 UCSF GRCh37 4 79856412 79856412 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 58 37 80 0 ENST00000512733.1:c.211G>A p.Val71Ile p.V71I ENST00000512733 NM_001040202.1 71 Gta/Ata 0 +PARD3B UCSF GRCh37 2 206037097 206037097 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 14 37 0 ENST00000358768.2:c.1597C>T p.Pro533Ser p.P533S ENST00000358768 533 Cca/Tca 0 +PARM1 UCSF GRCh37 4 75938106 75938106 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 97 49 110 0 ENST00000307428.7:c.515C>T p.Ser172Phe p.S172F ENST00000307428 NM_015393.3 172 tCc/tTc 0 +PARS2 UCSF GRCh37 1 55223436 55223436 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 22 35 0 ENST00000371279.3:c.1399G>A p.Asp467Asn p.D467N ENST00000371279 NM_152268.3 467 Gat/Aat 0 +PBRM1 UCSF GRCh37 3 52588816 52588816 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 4 11 15 0 ENST00000394830.3:c.4212G>A p.Gln1404= p.Q1404= ENST00000394830 NM_018313.4 1404 caG/caA 0 +PCDH12 UCSF GRCh37 5 141334941 141334941 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 4 16 0 ENST00000231484.3:c.2476C>T p.Leu826= p.L826= ENST00000231484 NM_016580.3 826 Ctg/Ttg 0 +PCDH15 UCSF GRCh37 10 55581869 55581869 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 135 18 140 0 ENST00000361849.3:c.5623A>G p.Thr1875Ala p.T1875A ENST00000361849 NM_001142768.1 1875 Aca/Gca 0 +PCDH15 UCSF GRCh37 10 55591215 55591215 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 47 85 0 ENST00000361849.3:c.4062C>T p.Ile1354= p.I1354= ENST00000361849 NM_001142768.1 1354 atC/atT 0 +PCDH9 UCSF GRCh37 13 66879031 66879031 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 9 66 0 ENST00000544246.1:c.3470C>T p.Pro1157Leu p.P1157L ENST00000544246 NM_203487.2 1157 cCt/cTt 0 +PCDHA1 UCSF GRCh37 5 140167217 140167217 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 26 37 0 ENST00000504120.2:c.1342G>A p.Val448Met p.V448M ENST00000504120 NM_018900.2 448 Gtg/Atg 0 +PCDHA2 UCSF GRCh37 5 140176090 140176090 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 8 15 0 ENST00000526136.1:c.1541G>A p.Ser514Asn p.S514N ENST00000526136 NM_018905.2 514 aGc/aAc 0 +PCDHA3 UCSF GRCh37 5 140182041 140182041 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 33 76 0 ENST00000522353.2:c.1259C>T p.Ala420Val p.A420V ENST00000522353 NM_018906.2 420 gCc/gTc 0 +PCDHB12 UCSF GRCh37 5 140590444 140590444 + synonymous_variant Silent SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 19 4 17 1 ENST00000239450.2:c.1965C>G p.Thr655= p.T655= ENST00000239450 NM_018932.3 655 acC/acG 0 +PCDHB16 UCSF GRCh37 5 140564227 140564227 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 8 30 0 ENST00000361016.2:c.2093C>T p.Ser698Leu p.S698L ENST00000361016 NM_020957.1 698 tCg/tTg 0 +PCDHB3 UCSF GRCh37 5 140481391 140481391 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 28 64 0 ENST00000231130.2:c.1158G>A p.Glu386= p.E386= ENST00000231130 NM_018937.2 386 gaG/gaA 0 +PCDHB8 UCSF GRCh37 5 140559730 140559730 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 15 38 0 ENST00000239444.2:c.2115G>A p.Ser705= p.S705= ENST00000239444 NM_019120.3 705 tcG/tcA 0 +PCDHGA1 UCSF GRCh37 5 140710722 140710722 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 51 104 0 ENST00000517417.1:c.471G>A p.Gly157= p.G157= ENST00000517417 NM_018912.2 157 ggG/ggA 0 +PCDHGB1 UCSF GRCh37 5 140729899 140729899 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 8 25 0 ENST00000523390.1:c.72C>T p.Cys24= p.C24= ENST00000523390 NM_018922.2 24 tgC/tgT 0 +PCDHGB7 UCSF GRCh37 5 140798736 140798736 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 11 75 0 ENST00000398594.2:c.1310C>T p.Thr437Ile p.T437I ENST00000398594 NM_018927.3 437 aCc/aTc 0 +PCDHGC4 UCSF GRCh37 5 140866462 140866462 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 23 40 0 ENST00000306593.1:c.1722C>T p.Ser574= p.S574= ENST00000306593 NM_018928.2 574 tcC/tcT 0 +PCDHGC5 UCSF GRCh37 5 140868812 140868812 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 10 21 0 ENST00000252087.1:c.5G>A p.Gly2Glu p.G2E ENST00000252087 NM_018929.2 2 gGg/gAg 0 +PCK2 UCSF GRCh37 14 24568906 24568906 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 14 29 0 ENST00000216780.4:c.992C>T p.Ala331Val p.A331V ENST00000216780 NM_004563.2 331 gCt/gTt 0 +PCLO UCSF GRCh37 7 82579900 82579900 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 99 23 81 0 ENST00000333891.9:c.10004C>T p.Ala3335Val p.A3335V ENST00000333891 NM_033026.5 3335 gCa/gTa 0 +PCNT UCSF GRCh37 21 47766078 47766078 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 10 24 0 ENST00000359568.5:c.676C>T p.Leu226= p.L226= ENST00000359568 NM_006031.5 226 Ctg/Ttg 0 +PDCD11 UCSF GRCh37 10 105202186 105202186 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 23 38 0 ENST00000369797.3:c.4924G>A p.Ala1642Thr p.A1642T ENST00000369797 NM_014976.1 1642 Gct/Act 0 +PDCD6IP UCSF GRCh37 3 33877759 33877759 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 39 95 0 ENST00000457054.2:c.1072+1G>A p.X358_splice ENST00000457054 NM_013374.5 0 +PDE4A UCSF GRCh37 19 10577842 10577842 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 18 37 0 ENST00000352831.6:c.2206G>A p.Ala736Thr p.A736T ENST00000352831 NM_001111307.1 736 Gcg/Acg 0 +PDE5A UCSF GRCh37 4 120463649 120463649 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 23 53 0 ENST00000354960.3:c.1537G>A p.Glu513Lys p.E513K ENST00000354960 NM_001083.3 513 Gag/Aag 0 +PDE8A UCSF GRCh37 15 85634350 85634350 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 24 43 0 ENST00000310298.4:c.790C>T p.Pro264Ser p.P264S ENST00000310298 264 Cct/Tct 0 +PDGFRL UCSF GRCh37 8 17491717 17491717 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 74 16 71 0 ENST00000541323.1:c.934C>T p.Gln312Ter p.Q312* ENST00000541323 NM_006207.2 312 Cag/Tag 0 +PDIA4 UCSF GRCh37 7 148703056 148703056 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 4 20 0 ENST00000286091.4:c.1221G>A p.Lys407= p.K407= ENST00000286091 NM_004911.4 407 aaG/aaA 0 +PDPK1 UCSF GRCh37 16 2607947 2607947 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 16 75 0 ENST00000342085.4:c.268G>A p.Glu90Lys p.E90K ENST00000342085 NM_002613.4 90 Gaa/Aaa 0 +PDPR UCSF GRCh37 16 70165289 70165289 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 34 161 0 ENST00000288050.4:c.814C>T p.Pro272Ser p.P272S ENST00000288050 NM_017990.3 272 Ccc/Tcc 0 +PDS5B UCSF GRCh37 13 33275510 33275510 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 86 44 123 0 ENST00000315596.10:c.1791C>T p.Phe597= p.F597= ENST00000315596 NM_015032.3 597 ttC/ttT 0 +PEG3 UCSF GRCh37 19 57326617 57326617 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 4 64 0 ENST00000326441.9:c.3193G>A p.Gly1065Ser p.G1065S ENST00000326441 NM_006210.2 1065 Ggc/Agc 0 +PELI2 UCSF GRCh37 14 56763632 56763632 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 22 65 0 ENST00000267460.4:c.1011G>A p.Met337Ile p.M337I ENST00000267460 NM_021255.2 337 atG/atA 0 +PER2 UCSF GRCh37 2 239161738 239161738 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 6 20 0 ENST00000254657.3:c.2926G>A p.Ala976Thr p.A976T ENST00000254657 NM_022817.2 976 Gcc/Acc 0 +PFAS UCSF GRCh37 17 8166462 8166462 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 11 54 0 ENST00000314666.6:c.1446G>A p.Gly482= p.G482= ENST00000314666 NM_012393.2 482 ggG/ggA 0 +PFAS UCSF GRCh37 17 8167880 8167880 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 3 14 0 ENST00000314666.6:c.2010G>A p.Arg670= p.R670= ENST00000314666 NM_012393.2 670 agG/agA 0 +PFKFB2 UCSF GRCh37 1 207252331 207252331 + downstream_gene_variant 3'Flank SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 6 27 0 ENST00000367080 NM_006212.2 0 +PGBD3 UCSF GRCh37 10 50723790 50723790 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 173 20 160 0 ENST00000374127.3:c.1371C>T p.Asn457= p.N457= ENST00000374127 NM_170753.3 457 aaC/aaT 0 +PGM1 UCSF GRCh37 1 64117389 64117389 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 8 35 0 ENST00000371083.4:c.1384G>A p.Asp462Asn p.D462N ENST00000371083 NM_001172818.1 462 Gac/Aac 0 +PGR UCSF GRCh37 11 100999666 100999666 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 11 16 0 ENST00000325455.5:c.136C>T p.Pro46Ser p.P46S ENST00000325455 NM_001202474.3 46 Cct/Tct 0 +PHC2 UCSF GRCh37 1 33820166 33820166 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 7 16 0 ENST00000257118.5:c.1391C>T p.Pro464Leu p.P464L ENST00000257118 NM_198040.2 464 cCc/cTc 0 +PHF17 UCSF GRCh37 4 129778576 129778576 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 87 58 115 0 ENST00000226319.6:c.948C>T p.Ser316= p.S316= ENST00000226319 NM_199320.2 316 agC/agT 0 +PHF2 UCSF GRCh37 9 96425291 96425291 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 64 9 42 0 ENST00000359246.4:c.1801G>A p.Ala601Thr p.A601T ENST00000359246 NM_005392.3 601 Gcc/Acc 0 +PHF2 UCSF GRCh37 9 96439887 96439887 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 137 41 105 0 ENST00000359246.4:c.3220G>A p.Gly1074Ser p.G1074S ENST00000359246 NM_005392.3 1074 Ggc/Agc 0 +PHF2 UCSF GRCh37 9 96437996 96437996 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 7 22 0 ENST00000359246.4:c.2757G>A p.Arg919= p.R919= ENST00000359246 NM_005392.3 919 agG/agA 0 +PHF21A UCSF GRCh37 11 45991440 45991440 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 11 17 0 ENST00000418153.2:c.625C>T p.Pro209Ser p.P209S ENST00000418153 209 Cct/Tct 0 +PI4KA UCSF GRCh37 22 21107225 21107225 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 50 93 0 ENST00000255882.6:c.2953G>A p.Val985Met p.V985M ENST00000255882 NM_058004.3 985 Gtg/Atg 0 +PI4KA UCSF GRCh37 22 21104219 21104219 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 3 18 0 ENST00000255882.6:c.3217C>T p.Pro1073Ser p.P1073S ENST00000255882 NM_058004.3 1073 Cct/Tct 0 +PIAS1 UCSF GRCh37 15 68438994 68438994 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 40 121 0 ENST00000249636.6:c.784G>A p.Val262Ile p.V262I ENST00000249636 NM_016166.1 262 Gta/Ata 0 +PIBF1 UCSF GRCh37 13 73357725 73357725 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 106 16 100 0 ENST00000326291.6:c.118C>T p.Arg40Ter p.R40* ENST00000326291 NM_006346.2 40 Cga/Tga 0 +PIGM UCSF GRCh37 1 160000672 160000672 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 92 16 109 0 ENST00000368090.2:c.858G>A p.Trp286Ter p.W286* ENST00000368090 NM_145167.2 286 tgG/tgA 0 +PIGX UCSF GRCh37 3 196454922 196454922 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 23 136 0 ENST00000296333.5:c.447C>T p.His149= p.H149= ENST00000296333 NM_001166304.1 149 caC/caT 0 +PILRA UCSF GRCh37 7 99997491 99997491 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 47 0 ENST00000198536.2:c.873C>T p.Ser291= p.S291= ENST00000198536 NM_013439.2 291 agC/agT 0 +PITPNM3 UCSF GRCh37 17 6387053 6387053 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 8 13 0 ENST00000262483.8:c.371C>T p.Ser124Phe p.S124F ENST00000262483 NM_031220.3 124 tCc/tTc 0 +PITPNM3 UCSF GRCh37 17 6381403 6381403 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 12 24 0 ENST00000262483.8:c.792G>A p.Gly264= p.G264= ENST00000262483 NM_031220.3 264 ggG/ggA 0 +PIWIL4 UCSF GRCh37 11 94340784 94340784 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 51 9 44 0 ENST00000299001.6:c.1818G>A p.Glu606= p.E606= ENST00000299001 NM_152431.2 606 gaG/gaA 0 +PKHD1L1 UCSF GRCh37 8 110457088 110457088 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 119 84 146 0 ENST00000378402.5:c.4990G>A p.Val1664Met p.V1664M ENST00000378402 NM_177531.4 1664 Gtg/Atg 0 +PKHD1L1 UCSF GRCh37 8 110447525 110447525 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 133 33 146 0 ENST00000378402.5:c.3447C>T p.Phe1149= p.F1149= ENST00000378402 NM_177531.4 1149 ttC/ttT 0 +PKP3 UCSF GRCh37 11 397590 397590 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 7 23 0 ENST00000331563.2:c.996C>T p.Asp332= p.D332= ENST00000331563 NM_007183.2 332 gaC/gaT 0 +PLA2G2A UCSF GRCh37 1 20304605 20304605 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 15 34 0 ENST00000375111.3:c.195C>T p.Val65= p.V65= ENST00000375111 NM_001161727.1 65 gtC/gtT 0 +PLA2G5 UCSF GRCh37 1 20417094 20417094 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 7 45 0 ENST00000375108.3:c.326C>T p.Ala109Val p.A109V ENST00000375108 NM_000929.2 109 gCc/gTc 0 +PLAC1 UCSF GRCh37 X 133700690 133700690 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 21 49 0 ENST00000359237.4:c.23G>A p.Gly8Glu p.G8E ENST00000359237 NM_021796.3 8 gGa/gAa 0 +PLAC8 UCSF GRCh37 4 84026056 84026056 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 27 83 0 ENST00000426923.2:c.236G>A p.Gly79Asp p.G79D ENST00000426923 NM_001130715.1 79 gGc/gAc 0 +PLB1 UCSF GRCh37 2 28847925 28847925 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 23 45 0 ENST00000327757.5:c.3529G>A p.Asp1177Asn p.D1177N ENST00000327757 NM_153021.4 1177 Gac/Aac 0 +PLCB1 UCSF GRCh37 20 8626764 8626764 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 14 61 0 ENST00000338037.6:c.400G>A p.Val134Ile p.V134I ENST00000338037 NM_015192.3 134 Gtt/Att 0 +PLCD1 UCSF GRCh37 3 38049598 38049598 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 4 38 0 ENST00000463876.1:c.2155G>A p.Ala719Thr p.A719T ENST00000463876 NM_001130964.1 719 Gcc/Acc 0 +PLCD4 UCSF GRCh37 2 219492808 219492808 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 24 44 0 ENST00000450993.2:c.829G>A p.Asp277Asn p.D277N ENST00000450993 NM_032726.3 277 Gat/Aat 0 +PLCE1 UCSF GRCh37 10 95892040 95892040 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 45 82 0 ENST00000371380.3:c.1316G>A p.Gly439Asp p.G439D ENST00000371380 439 gGt/gAt 0 +PLCL2 UCSF GRCh37 3 17051554 17051554 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 73 10 159 0 ENST00000418129.2:c.338C>T p.Ala113Val p.A113V ENST00000418129 NM_001144382.1 113 gCa/gTa 0 +PLD5 UCSF GRCh37 1 242253290 242253290 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 121 25 125 0 ENST00000536534.2:c.1477G>A p.Asp493Asn p.D493N ENST00000536534 493 Gac/Aac 0 +PLDN UCSF GRCh37 15 45898679 45898679 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 85 13 105 0 ENST00000220531.3:c.486G>A p.Lys162= p.K162= ENST00000220531 NM_012388.2 162 aaG/aaA 0 +PLEKHG5 UCSF GRCh37 1 6535115 6535115 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 79 17 51 0 ENST00000537245.1:c.531G>A p.Lys177= p.K177= ENST00000537245 NM_001265592.1 177 aaG/aaA 0 +PLIN4 UCSF GRCh37 19 4511488 4511488 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 89 61 116 0 ENST00000301286.3:c.2442C>T p.Thr814= p.T814= ENST00000301286 NM_001080400.1 814 acC/acT 0 +PLK1 UCSF GRCh37 16 23700000 23700000 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 9 32 0 ENST00000300093.4:c.1204G>A p.Asp402Asn p.D402N ENST00000300093 NM_005030.3 402 Gat/Aat 0 +PLK3 UCSF GRCh37 1 45270013 45270013 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 23 17 0 ENST00000372201.4:c.1345G>A p.Glu449Lys p.E449K ENST00000372201 NM_004073.2 449 Gaa/Aaa 0 +PLS3 UCSF GRCh37 X 114883769 114883769 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 10 29 1 ENST00000420625.2:c.1781G>A p.Arg594Lys p.R594K ENST00000420625 NM_001136025.3 594 aGa/aAa 0 +PLXNA2 UCSF GRCh37 1 208218077 208218077 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 7 17 0 ENST00000367033.3:c.3650G>A p.Gly1217Asp p.G1217D ENST00000367033 NM_025179.3 1217 gGc/gAc 0 +PLXNA4 UCSF GRCh37 7 131883310 131883310 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 14 21 0 ENST00000359827.3:c.2672C>T p.Ala891Val p.A891V ENST00000359827 891 gCc/gTc 0 +PLXNA4 UCSF GRCh37 7 131888097 131888097 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 9 28 0 ENST00000359827.3:c.2380C>T p.Pro794Ser p.P794S ENST00000359827 794 Cca/Tca 0 +PLXNB3 UCSF GRCh37 X 153036320 153036320 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 3 12 0 ENST00000538966.1:c.2187G>A p.Arg729= p.R729= ENST00000538966 NM_001163257.1 729 cgG/cgA 0 +PLXNC1 UCSF GRCh37 12 94697645 94697645 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 16 105 0 ENST00000258526.4:c.4500G>A p.Met1500Ile p.M1500I ENST00000258526 NM_005761.2 1500 atG/atA 0 +PNKD UCSF GRCh37 2 219209653 219209653 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 8 45 0 ENST00000273077.4:c.1107C>T p.Ala369= p.A369= ENST00000273077 NM_015488.4 369 gcC/gcT 0 +PNLDC1 UCSF GRCh37 6 160224997 160224997 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 21 102 0 ENST00000610273.1:c.216G>A p.Lys72= p.K72= ENST00000610273 NM_173516.2 72 aaG/aaA 0 +PNMA3 UCSF GRCh37 X 152225506 152225506 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0025 P01_Rec Untested WXS Illumina HiSeq 7 24 24 0 ENST00000447306.1:c.94G>A p.Glu32Lys p.E32K ENST00000447306 NM_013364.4 32 Gag/Aag 0 +PNMA5 UCSF GRCh37 X 152159173 152159173 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 4 28 0 ENST00000439251.1:c.970C>T p.Leu324Phe p.L324F ENST00000439251 NM_001103150.1 324 Ctc/Ttc 0 +POLE UCSF GRCh37 12 133253196 133253196 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 8 35 0 ENST00000320574.5:c.845C>T p.Pro282Leu p.P282L ENST00000320574 NM_006231.2 282 cCc/cTc 0 +POLE2 UCSF GRCh37 14 50130071 50130071 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 16 53 0 ENST00000216367.5:c.717C>T p.Ala239= p.A239= ENST00000216367 NM_002692.3 239 gcC/gcT 0 +POLR1A UCSF GRCh37 2 86258542 86258542 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 11 33 0 ENST00000263857.6:c.4489G>A p.Ala1497Thr p.A1497T ENST00000263857 1497 Gcc/Acc 0 +POLR1B UCSF GRCh37 2 113300155 113300155 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 13 22 0 ENST00000263331.5:c.84G>A p.Arg28= p.R28= ENST00000263331 NM_019014.4 28 cgG/cgA 0 +POLR2A UCSF GRCh37 17 7400674 7400674 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 4 24 0 ENST00000322644.6:c.820-1G>A p.X274_splice ENST00000322644 NM_000937.4 0 +POLR2E UCSF GRCh37 19 1093980 1093980 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 8 18 0 ENST00000215587.7:c.155G>A p.Arg52Gln p.R52Q ENST00000215587 52 cGg/cAg 0 +POMT2 UCSF GRCh37 14 77755164 77755164 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 22 57 0 ENST00000261534.4:c.1194C>T p.Asp398= p.D398= ENST00000261534 NM_013382.5 398 gaC/gaT 0 +POTEE UCSF GRCh37 2 132010673 132010673 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 119 25 224 0 ENST00000356920.5:c.1778+1G>A p.X593_splice ENST00000356920 NM_001083538.1 0 +POTEF UCSF GRCh37 2 130832864 130832864 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 24 88 0 ENST00000357462.5:c.2181C>T p.Pro727= p.P727= ENST00000357462 727 ccC/ccT 0 +PPFIA2 UCSF GRCh37 12 81734921 81734921 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 26 80 0 ENST00000549396.1:c.2329C>T p.Pro777Ser p.P777S ENST00000549396 NM_003625.3 777 Cct/Tct 0 +PPFIBP1 UCSF GRCh37 12 27844782 27844782 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 121 22 122 0 ENST00000318304.8:c.2804G>A p.Gly935Glu p.G935E ENST00000318304 NM_177444.2 935 gGa/gAa 0 +PPHLN1 UCSF GRCh37 12 42745695 42745695 + stop_gained Nonsense_Mutation SNP C C A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 9 38 0 ENST00000395568.2:c.81C>A p.Tyr27Ter p.Y27* ENST00000395568 NM_016488.6 27 taC/taA 0 +PPIL1 UCSF GRCh37 6 36839493 36839493 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 169 43 130 0 ENST00000373699.5:c.211+1G>A p.X71_splice ENST00000373699 NM_016059.4 0 +PPIP5K2 UCSF GRCh37 5 102526558 102526558 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 36 128 0 ENST00000321521.9:c.3305C>T p.Ser1102Phe p.S1102F ENST00000321521 1102 tCc/tTc 0 +PPIP5K2 UCSF GRCh37 5 102526637 102526637 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 89 51 151 0 ENST00000321521.9:c.3384C>T p.Ser1128= p.S1128= ENST00000321521 1128 tcC/tcT 0 +PPL UCSF GRCh37 16 4934721 4934721 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 105 67 135 0 ENST00000345988.2:c.3935G>A p.Arg1312Lys p.R1312K ENST00000345988 NM_002705.4 1312 aGg/aAg 0 +PPM1G UCSF GRCh37 2 27606392 27606392 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 12 43 0 ENST00000344034.4:c.1042G>A p.Asp348Asn p.D348N ENST00000344034 NM_177983.2 348 Gac/Aac 0 +PPM1H UCSF GRCh37 12 63114037 63114037 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 42 112 0 ENST00000228705.6:c.987G>A p.Glu329= p.E329= ENST00000228705 NM_020700.1 329 gaG/gaA 0 +PPP2R1B UCSF GRCh37 11 111608252 111608252 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 6 25 0 ENST00000311129.5:c.1831G>A p.Asp611Asn p.D611N ENST00000311129 NM_181699.2 611 Gac/Aac 0 +PPP6R2 UCSF GRCh37 22 50876724 50876724 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 15 0 ENST00000395741.3:c.1883C>T p.Pro628Leu p.P628L ENST00000395741 628 cCc/cTc 0 +PPRC1 UCSF GRCh37 10 103899228 103899228 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 22 34 0 ENST00000278070.2:c.963C>T p.Thr321= p.T321= ENST00000278070 NM_015062.3 321 acC/acT 0 +PRB1 UCSF GRCh37 12 11506577 11506577 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 10 42 0 ENST00000500254.2:c.313+147C>T *105* ENST00000500254 NM_199353.2 0 +PRB4 UCSF GRCh37 12 11461462 11461462 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 172 22 157 0 ENST00000279575.1:c.455C>T p.Ser152Phe p.S152F ENST00000279575 NM_001261399.1 152 tCc/tTc 0 +PRCC UCSF GRCh37 1 156770198 156770198 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 22 50 0 ENST00000271526.4:c.1422C>T p.Thr474= p.T474= ENST00000271526 NM_005973.4 474 acC/acT 0 +PRDM10 UCSF GRCh37 11 129785651 129785651 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 6 46 0 ENST00000358825.5:c.2442G>A p.Glu814= p.E814= ENST00000358825 NM_020228.2 814 gaG/gaA 0 +PRDM15 UCSF GRCh37 21 43258144 43258144 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 36 47 0 ENST00000269844.3:c.1998C>T p.Val666= p.V666= ENST00000269844 NM_022115.3 666 gtC/gtT 0 +PRDM2 UCSF GRCh37 1 14106686 14106686 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 30 44 0 ENST00000235372.7:c.2396G>A p.Cys799Tyr p.C799Y ENST00000235372 NM_012231.4 799 tGc/tAc 0 +PRDM5 UCSF GRCh37 4 121742370 121742370 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 132 24 141 0 ENST00000264808.3:c.431G>A p.Gly144Glu p.G144E ENST00000264808 NM_018699.2 144 gGg/gAg 0 +PRDM6 UCSF GRCh37 5 122515955 122515955 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.003,1000g2011may_all_0.00696 P01_Rec Untested WXS Illumina HiSeq 44 5 39 0 ENST00000407847.4:c.1611C>T p.Ala537= p.A537= ENST00000407847 NM_001136239.1 537 gcC/gcT 0 +PRDM8 UCSF GRCh37 4 81122444 81122444 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 27 35 0 ENST00000339711.4:c.220G>A p.Val74Ile p.V74I ENST00000339711 NM_020226.3 74 Gta/Ata 0 +PREX2 UCSF GRCh37 8 68939559 68939559 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 11 92 1 ENST00000288368.4:c.543+1G>A p.X181_splice ENST00000288368 NM_024870.2 0 +PRICKLE2 UCSF GRCh37 3 64184506 64184506 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 12 69 0 ENST00000295902.6:c.98C>T p.Ala33Val p.A33V ENST00000295902 NM_198859.3 33 gCt/gTt 0 +PRKAB1 UCSF GRCh37 12 120114413 120114413 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 28 51 0 ENST00000229328.5:c.604G>A p.Ala202Thr p.A202T ENST00000229328 NM_006253.4 202 Gca/Aca 0 +PRKCD UCSF GRCh37 3 53222751 53222751 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 13 54 0 ENST00000394729.2:c.1431C>T p.Asp477= p.D477= ENST00000394729 NM_212539.1 477 gaC/gaT 0 +PRND UCSF GRCh37 20 4705476 4705476 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 8 20 0 ENST00000305817.2:c.279C>T p.Gly93= p.G93= ENST00000305817 NM_012409.2 93 ggC/ggT 0 +PROC UCSF GRCh37 2 128186326 128186326 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 9 29 0 ENST00000234071.3:c.1190C>T p.Ala397Val p.A397V ENST00000234071 NM_000312.3 397 gCc/gTc 0 +PROL1 UCSF GRCh37 4 71275779 71275779 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 56 7 62 0 ENST00000399575.2:c.734C>T p.Ala245Val p.A245V ENST00000399575 NM_021225.4 245 gCc/gTc 0 +PROP1 UCSF GRCh37 5 177421246 177421246 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 10 32 0 ENST00000308304.2:c.203C>T p.Ser68Phe p.S68F ENST00000308304 NM_006261.4 68 tCc/tTc 0 +PROX1 UCSF GRCh37 1 214170923 214170923 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 26 74 0 ENST00000366958.4:c.1045G>A p.Ala349Thr p.A349T ENST00000366958 NM_001270616.1 349 Gct/Act 0 +PRPF38B UCSF GRCh37 1 109242410 109242410 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 34 111 0 ENST00000370025.4:c.1409G>A p.Arg470Gln p.R470Q ENST00000370025 NM_018061.2 470 cGa/cAa 0 +PRR14L UCSF GRCh37 22 32112452 32112452 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 133 26 154 0 ENST00000327423.6:c.1373C>T p.Ser458Phe p.S458F ENST00000327423 NM_173566.2 458 tCt/tTt 0 +PRR5L UCSF GRCh37 11 36422804 36422804 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 13 0 ENST00000378867.3:c.133C>T p.Leu45= p.L45= ENST00000378867 NM_024841.4 45 Ctg/Ttg 0 +PRRC2B UCSF GRCh37 9 134351008 134351008 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 9 27 0 ENST00000357304.4:c.3492G>A p.Arg1164= p.R1164= ENST00000357304 NM_013318.3 1164 agG/agA 0 +PRUNE2 UCSF GRCh37 9 79465386 79465386 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 8 62 0 ENST00000376718.3:c.337C>T p.Leu113= p.L113= ENST00000376718 NM_015225.2 113 Ctg/Ttg 0 +PSG6 UCSF GRCh37 19 43414818 43414818 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 139 79 157 0 ENST00000292125.2:c.620C>T p.Thr207Ile p.T207I ENST00000292125 NM_002782.4 207 aCa/aTa 0 +PSG7 UCSF GRCh37 19 43430146 43430146 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 98 80 150 0 ENST00000406070.2:c.1022T>C p.Phe341Ser p.F341S ENST00000406070 NM_002783.2 341 tTc/tCc 0 +PSMD1 UCSF GRCh37 2 231944942 231944942 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 8 45 0 ENST00000308696.6:c.1327C>T p.Leu443Phe p.L443F ENST00000308696 NM_002807.3 443 Ctc/Ttc 0 +PSMD13 UCSF GRCh37 11 248855 248855 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 32 45 0 ENST00000431206.2:c.654C>T p.Leu218= p.L218= ENST00000431206 NM_175932.2 218 ctC/ctT 0 +PSMD2 UCSF GRCh37 3 184017696 184017696 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 25 74 0 ENST00000310118.4:c.192+1G>A p.X64_splice ENST00000310118 NM_002808.4 0 +PSPC1 UCSF GRCh37 13 20346466 20346466 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 13 73 0 ENST00000338910.4:c.590G>A p.Gly197Glu p.G197E ENST00000338910 NM_001042414.2 197 gGa/gAa 0 +PSTPIP1 UCSF GRCh37 15 77323605 77323605 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 12 37 0 ENST00000558012.1:c.727G>A p.Val243Ile p.V243I ENST00000558012 NM_003978.3 243 Gtc/Atc 0 +PTEN UCSF GRCh37 10 89690824 89690824 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 25 57 0 ENST00000371953.3:c.231C>T p.Asp77= p.D77= ENST00000371953 NM_000314.4 77 gaC/gaT 0 +PTGER4 UCSF GRCh37 5 40692104 40692104 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 6 47 0 ENST00000302472.3:c.1091C>T p.Ser364Leu p.S364L ENST00000302472 NM_000958.2 364 tCa/tTa 0 +PTGS1 UCSF GRCh37 9 125143830 125143830 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 13 31 0 ENST00000362012.2:c.677G>A p.Gly226Glu p.G226E ENST00000362012 NM_000962.3 226 gGg/gAg 0 +PTK7 UCSF GRCh37 6 43109797 43109797 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 10 21 0 ENST00000481273.1:c.1921G>A p.Asp641Asn p.D641N ENST00000481273 NM_001270398.1 641 Gac/Aac 0 +PTK7 UCSF GRCh37 6 43098292 43098292 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 33 8 9 0 ENST00000481273.1:c.729A>G p.Val243= p.V243= ENST00000481273 NM_001270398.1 243 gtA/gtG 0 +PTPN13 UCSF GRCh37 4 87690936 87690936 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 22 66 0 ENST00000436978.1:c.4519G>A p.Val1507Ile p.V1507I ENST00000436978 NM_080685.2 1507 Gta/Ata 0 +PTPN13 UCSF GRCh37 4 87731108 87731108 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 53 85 0 ENST00000436978.1:c.7285G>A p.Val2429Ile p.V2429I ENST00000436978 NM_080685.2 2429 Gtt/Att 0 +PTPN14 UCSF GRCh37 1 214546053 214546053 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 29 79 0 ENST00000366956.5:c.3036+1G>A p.X1012_splice ENST00000366956 NM_005401.4 0 +PTPN18 UCSF GRCh37 2 131128349 131128349 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 5 28 0 ENST00000175756.5:c.828G>A p.Gln276= p.Q276= ENST00000175756 NM_014369.3 276 caG/caA 0 +PTPRD UCSF GRCh37 9 8524986 8524986 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 7 100 0 ENST00000356435.5:c.618G>A p.Glu206= p.E206= ENST00000356435 206 gaG/gaA 0 +PTPRH UCSF GRCh37 19 55708101 55708101 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 9 13 0 ENST00000376350.3:c.2046C>T p.Val682= p.V682= ENST00000376350 NM_002842.3 682 gtC/gtT 0 +PTPRJ UCSF GRCh37 11 48145317 48145317 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 33 60 0 ENST00000418331.2:c.769G>A p.Val257Ile p.V257I ENST00000418331 NM_002843.3 257 Gtc/Atc 0 +PTPRQ UCSF GRCh37 12 81064145 81064145 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 13 100 0 ENST00000266688.5:c.6464G>A p.Arg2155Gln p.R2155Q ENST00000266688 2155 cGa/cAa 0 +PTPRS UCSF GRCh37 19 5231373 5231373 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 3 11 0 ENST00000357368.4:c.2103G>A p.Glu701= p.E701= ENST00000357368 NM_002850.3 701 gaG/gaA 0 +PTPRT UCSF GRCh37 20 41514503 41514503 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 35 10 29 0 ENST00000373198.4:c.158C>T p.Thr53Ile p.T53I ENST00000373198 NM_133170.3 53 aCc/aTc 0 +PTTG1IP UCSF GRCh37 21 46276217 46276217 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 13 26 0 ENST00000330938.3:c.340G>A p.Ala114Thr p.A114T ENST00000330938 NM_004339.3 114 Gcc/Acc 0 +PWP2 UCSF GRCh37 21 45550639 45550639 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 4 39 0 ENST00000291576.7:c.2746G>A p.Glu916Lys p.E916K ENST00000291576 NM_005049.2 916 Gag/Aag 0 +PXDNL UCSF GRCh37 8 52321585 52321585 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 20 30 0 ENST00000356297.4:c.2599C>T p.Pro867Ser p.P867S ENST00000356297 NM_144651.4 867 Ccc/Tcc 0 +PYGO2 UCSF GRCh37 1 154932010 154932010 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 9 21 0 ENST00000368457.2:c.466C>T p.Pro156Ser p.P156S ENST00000368457 NM_138300.3 156 Ccc/Tcc 0 +QARS UCSF GRCh37 3 49136792 49136792 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 7 28 0 ENST00000306125.6:c.1599C>T p.Asn533= p.N533= ENST00000306125 NM_001272073.1 533 aaC/aaT 0 +QKI UCSF GRCh37 6 163986999 163986999 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 29 60 0 ENST00000361752.3:c.935-754G>A *312* ENST00000361752 NM_006775.2 0 +RAB3GAP2 UCSF GRCh37 1 220340977 220340977 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 59 114 0 ENST00000358951.2:c.2847G>A p.Gln949= p.Q949= ENST00000358951 NM_012414.3 949 caG/caA 0 +RAB5B UCSF GRCh37 12 56380896 56380896 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 33 20 44 0 ENST00000360299.5:c.152G>A p.Ser51Asn p.S51N ENST00000360299 NM_002868.3 51 aGc/aAc 0 +RAB7A UCSF GRCh37 3 128514263 128514263 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 18 79 0 ENST00000265062.3:c.53G>A p.Gly18Glu p.G18E ENST00000265062 NM_004637.5 18 gGa/gAa 0 +RABL2A UCSF GRCh37 2 114392709 114392709 + splice_donor_variant Splice_Site SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 24 10 22 0 ENST00000393167.3:c.297+2T>C p.X99_splice ENST00000393167 NM_013412.2 0 +RAD17 UCSF GRCh37 5 68669849 68669849 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 100 17 119 0 ENST00000509734.1:c.235G>A p.Glu79Lys p.E79K ENST00000509734 79 Gaa/Aaa 0 +RAD50 UCSF GRCh37 5 131926937 131926937 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 104 23 95 0 ENST00000265335.6:c.1474G>A p.Glu492Lys p.E492K ENST00000265335 492 Gag/Aag 0 +RAG1 UCSF GRCh37 11 36595248 36595248 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 19 55 0 ENST00000299440.5:c.394C>T p.Pro132Ser p.P132S ENST00000299440 NM_000448.2 132 Cct/Tct 0 +RALGAPB UCSF GRCh37 20 37150153 37150153 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 56 45 102 0 ENST00000262879.6:c.1431A>G p.Gln477= p.Q477= ENST00000262879 477 caA/caG 0 +RALYL UCSF GRCh37 8 85441705 85441705 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 126 23 113 0 ENST00000517638.1:c.188G>A p.Gly63Glu p.G63E ENST00000517638 NM_001100391.1 63 gGa/gAa 0 +RAPGEF2 UCSF GRCh37 4 160264305 160264305 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 32 96 0 ENST00000264431.4:c.2610C>T p.Phe870= p.F870= ENST00000264431 NM_014247.2 870 ttC/ttT 0 +RASA3 UCSF GRCh37 13 114766378 114766378 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 47 12 52 0 ENST00000334062.7:c.1773G>A p.Lys591= p.K591= ENST00000334062 NM_007368.2 591 aaG/aaA 0 +RASGRP1 UCSF GRCh37 15 38852131 38852131 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 23 45 0 ENST00000310803.5:c.111C>T p.Ser37= p.S37= ENST00000310803 NM_005739.3 37 tcC/tcT 0 +RASGRP3 UCSF GRCh37 2 33774783 33774783 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 183 31 170 0 ENST00000403687.3:c.1507C>T p.Leu503Phe p.L503F ENST00000403687 NM_001139488.1 503 Ctc/Ttc 0 +RB1 UCSF GRCh37 13 49047527 49047527 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 44 36 101 0 ENST00000267163.4:c.2520+1G>A p.X840_splice ENST00000267163 NM_000321.2 0 +RBBP4 UCSF GRCh37 1 33134587 33134587 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 71 79 0 ENST00000373493.5:c.615G>A p.Trp205Ter p.W205* ENST00000373493 NM_005610.2 205 tgG/tgA 0 +RBL1 UCSF GRCh37 20 35672623 35672623 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 38 68 0 ENST00000373664.3:c.1636G>A p.Gly546Arg p.G546R ENST00000373664 NM_002895.3 546 Ggg/Agg 0 +RBM12 UCSF GRCh37 20 34241488 34241488 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 109 69 158 0 ENST00000374114.3:c.1757G>A p.Gly586Glu p.G586E ENST00000374114 NM_001198838.1 586 gGa/gAa 0 +RBM12B UCSF GRCh37 8 94748329 94748329 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 107 60 121 0 ENST00000399300.2:c.310G>A p.Asp104Asn p.D104N ENST00000399300 NM_203390.2 104 Gac/Aac 0 +RBM5 UCSF GRCh37 3 50144935 50144935 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 3 40 0 ENST00000347869.3:c.974G>A p.Gly325Asp p.G325D ENST00000347869 NM_005778.3 325 gGt/gAt 0 +RBP3 UCSF GRCh37 10 48388081 48388081 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 13 16 0 ENST00000224600.4:c.2797C>T p.Leu933= p.L933= ENST00000224600 NM_002900.2 933 Ctg/Ttg 0 +RECQL UCSF GRCh37 12 21639413 21639413 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 10 46 0 ENST00000421138.2:c.501G>A p.Lys167= p.K167= ENST00000421138 167 aaG/aaA 0 +RECQL5 UCSF GRCh37 17 73625024 73625024 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 14 34 0 ENST00000317905.5:c.2479G>A p.Glu827Lys p.E827K ENST00000317905 NM_004259.6 827 Gag/Aag 0 +RELN UCSF GRCh37 7 103194156 103194156 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 18 66 0 ENST00000428762.1:c.5920C>T p.Pro1974Ser p.P1974S ENST00000428762 NM_005045.3 1974 Cct/Tct 0 +RELN UCSF GRCh37 7 103194216 103194216 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 70 8 87 0 ENST00000428762.1:c.5860C>T p.Pro1954Ser p.P1954S ENST00000428762 NM_005045.3 1954 Cct/Tct 0 +REN UCSF GRCh37 1 204124220 204124220 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 6 27 0 ENST00000272190.8:c.1145G>A p.Gly382Glu p.G382E ENST00000272190 NM_000537.3 382 gGg/gAg 0 +REPS1 UCSF GRCh37 6 139265669 139265669 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 92 47 117 0 ENST00000258062.5:c.719G>A p.Ser240Asn p.S240N ENST00000258062 NM_031922.3 240 aGt/aAt 0 +RERE UCSF GRCh37 1 8526023 8526023 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 23 14 27 0 ENST00000337907.3:c.1165C>T p.Pro389Ser p.P389S ENST00000337907 NM_012102.3 389 Ccc/Tcc 0 +RERG UCSF GRCh37 12 15262121 15262121 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 50 24 65 0 ENST00000256953.2:c.523G>A p.Gly175Ser p.G175S ENST00000256953 NM_032918.2 175 Ggc/Agc 0 +RFWD3 UCSF GRCh37 16 74662375 74662375 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 23 69 0 ENST00000361070.4:c.1944G>A p.Arg648= p.R648= ENST00000361070 NM_018124.3 648 cgG/cgA 0 +RGL2 UCSF GRCh37 6 33263494 33263494 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 15 37 0 ENST00000497454.1:c.811C>T p.Leu271= p.L271= ENST00000497454 NM_004761.4 271 Ctg/Ttg 0 +RGMA UCSF GRCh37 15 93595396 93595396 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 4 10 0 ENST00000557301.1:c.496C>T p.Pro166Ser p.P166S ENST00000557301 NM_001166283.1 166 Ccc/Tcc 0 +RGS22 UCSF GRCh37 8 101011541 101011541 + missense_variant Missense_Mutation SNP C C G NOVEL P01_Rec Untested WXS Illumina HiSeq 24 6 69 0 ENST00000360863.6:c.2898G>C p.Trp966Cys p.W966C ENST00000360863 NM_015668.3 966 tgG/tgC 0 +RGS3 UCSF GRCh37 9 116359220 116359220 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 6 28 0 ENST00000374140.2:c.3584G>A p.Ser1195Asn p.S1195N ENST00000374140 NM_144488.5 1195 aGt/aAt 0 +RHOBTB2 UCSF GRCh37 8 22861992 22861992 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 7 13 0 ENST00000519685.1:c.111C>T p.Ile37= p.I37= ENST00000519685 NM_001160036.1 37 atC/atT 0 +RHOBTB2 UCSF GRCh37 8 22868110 22868110 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 25 40 0 ENST00000519685.1:c.1746C>T p.Thr582= p.T582= ENST00000519685 NM_001160036.1 582 acC/acT 0 +RHOT2 UCSF GRCh37 16 720939 720939 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 4 9 0 ENST00000315082.4:c.687G>A p.Val229= p.V229= ENST00000315082 NM_138769.2 229 gtG/gtA 0 +RHOU UCSF GRCh37 1 228879096 228879096 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 93 63 138 0 ENST00000366691.3:c.386G>A p.Ser129Asn p.S129N ENST00000366691 NM_021205.5 129 aGt/aAt 0 +RHOU UCSF GRCh37 1 228879263 228879263 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 107 16 119 0 ENST00000366691.3:c.553G>A p.Glu185Lys p.E185K ENST00000366691 NM_021205.5 185 Gaa/Aaa 0 +RIC3 UCSF GRCh37 11 8161680 8161680 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 5 61 0 ENST00000309737.6:c.185C>T p.Thr62Ile p.T62I ENST00000309737 62 aCt/aTt 0 +RIF1 UCSF GRCh37 2 152314421 152314421 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 20 76 0 ENST00000243326.5:c.2799G>A p.Gln933= p.Q933= ENST00000243326 933 caG/caA 0 +RIN1 UCSF GRCh37 11 66102639 66102639 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 9 0 ENST00000311320.4:c.631C>T p.Pro211Ser p.P211S ENST00000311320 NM_004292.2 211 Cct/Tct 0 +RIOK2 UCSF GRCh37 5 96514771 96514771 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 82 14 91 0 ENST00000283109.3:c.193G>A p.Glu65Lys p.E65K ENST00000283109 NM_018343.2 65 Gag/Aag 0 +RIPK2 UCSF GRCh37 8 90775185 90775185 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 85 14 110 0 ENST00000220751.4:c.302G>A p.Gly101Glu p.G101E ENST00000220751 NM_003821.5 101 gGa/gAa 0 +RIPK3 UCSF GRCh37 14 24805471 24805471 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 18 32 0 ENST00000216274.5:c.1467G>A p.Gln489= p.Q489= ENST00000216274 NM_006871.3 489 caG/caA 0 +RNASEH1 UCSF GRCh37 2 3593451 3593451 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 136 31 57 0 ENST00000315212.3:c.785C>T p.Pro262Leu p.P262L ENST00000315212 NM_002936.3 262 cCt/cTt 0 +RNF122 UCSF GRCh37 8 33408577 33408577 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 135 28 120 0 ENST00000256257.1:c.255G>A p.Lys85= p.K85= ENST00000256257 NM_024787.3 85 aaG/aaA 0 +RNF141 UCSF GRCh37 11 10536554 10536554 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 11 87 0 ENST00000265981.2:c.602C>T p.Ser201Phe p.S201F ENST00000265981 NM_016422.3 201 tCt/tTt 0 +RNF157 UCSF GRCh37 17 74148449 74148449 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 23 63 0 ENST00000269391.6:c.1908G>A p.Glu636= p.E636= ENST00000269391 NM_052916.2 636 gaG/gaA 0 +RNF17 UCSF GRCh37 13 25424490 25424490 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 6 27 0 ENST00000255324.5:c.3113G>A p.Gly1038Glu p.G1038E ENST00000255324 NM_031277.2 1038 gGg/gAg 0 +RNF186 UCSF GRCh37 1 20141433 20141433 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 6 16 0 ENST00000375121.2:c.162G>A p.Lys54= p.K54= ENST00000375121 NM_019062.1 54 aaG/aaA 0 +RNF19A UCSF GRCh37 8 101273935 101273935 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 14 70 0 ENST00000519449.1:c.1517G>A p.Gly506Glu p.G506E ENST00000519449 NM_015435.4 506 gGa/gAa 0 +RNF20 UCSF GRCh37 9 104324237 104324237 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 163 69 144 0 ENST00000389120.3:c.2695C>T p.Pro899Ser p.P899S ENST00000389120 NM_019592.6 899 Cca/Tca 0 +RNF213 UCSF GRCh37 17 78321193 78321193 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 18 38 0 ENST00000582970.1:c.9058C>T p.Gln3020Ter p.Q3020* ENST00000582970 NM_001256071.1 3020 Cag/Tag 0 +RNF41 UCSF GRCh37 12 56602029 56602029 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 30 7 29 0 ENST00000345093.4:c.416G>A p.Arg139His p.R139H ENST00000345093 NM_005785.3 139 cGc/cAc 0 +RNF43 UCSF GRCh37 17 56435144 56435144 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 19 34 0 ENST00000407977.2:c.1993C>T p.Pro665Ser p.P665S ENST00000407977 665 Cct/Tct 0 +RNGTT UCSF GRCh37 6 89614661 89614661 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 20 89 0 ENST00000369485.4:c.457G>A p.Val153Ile p.V153I ENST00000369485 NM_003800.3 153 Gtt/Att 0 +RNLS UCSF GRCh37 10 90034789 90034789 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 8 44 0 ENST00000371947.3:c.877G>A p.Val293Ile p.V293I ENST00000371947 NM_018363.3 293 Gta/Ata 0 +RNMT UCSF GRCh37 18 13742486 13742486 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 74 42 140 0 ENST00000383314.2:c.975-1G>A p.X325_splice ENST00000383314 0 +ROBO1 UCSF GRCh37 3 78689011 78689011 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 17 33 0 ENST00000464233.1:c.2920C>T p.Pro974Ser p.P974S ENST00000464233 NM_002941.3 974 Cca/Tca 0 +ROCK1 UCSF GRCh37 18 18690815 18690815 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 84 19 71 0 ENST00000399799.2:c.57G>A p.Arg19= p.R19= ENST00000399799 NM_005406.2 19 cgG/cgA 0 +ROS1 UCSF GRCh37 6 117609783 117609783 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 27 74 0 ENST00000368508.3:c.6916G>A p.Glu2306Lys p.E2306K ENST00000368508 NM_002944.2 2306 Gag/Aag 0 +ROS1 UCSF GRCh37 6 117686340 117686340 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 37 83 0 ENST00000368508.3:c.3001C>T p.Pro1001Ser p.P1001S ENST00000368508 NM_002944.2 1001 Cct/Tct 0 +RP1L1 UCSF GRCh37 8 10464582 10464582 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 122 26 84 0 ENST00000382483.3:c.7026G>A p.Arg2342= p.R2342= ENST00000382483 NM_178857.5 2342 agG/agA 0 +RP1L1 UCSF GRCh37 8 10468188 10468188 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 13 30 0 ENST00000382483.3:c.3420G>A p.Arg1140= p.R1140= ENST00000382483 NM_178857.5 1140 agG/agA 0 +RPAP1 UCSF GRCh37 15 41809836 41809836 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 21 97 0 ENST00000304330.4:c.4086G>A p.Glu1362= p.E1362= ENST00000304330 NM_015540.2 1362 gaG/gaA 0 +RPF1 UCSF GRCh37 1 84945059 84945059 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 10 30 0 ENST00000370654.5:c.95G>A p.Gly32Glu p.G32E ENST00000370654 NM_025065.6 32 gGg/gAg 0 +RPGRIP1 UCSF GRCh37 14 21793437 21793437 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 19 63 0 ENST00000400017.2:c.2262G>A p.Leu754= p.L754= ENST00000400017 NM_020366.3 754 ctG/ctA 0 +RPL30 UCSF GRCh37 8 99057222 99057222 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 55 103 0 ENST00000521291.1:c.116G>A p.Arg39Lys p.R39K ENST00000521291 39 aGa/aAa 0 +RPL7 UCSF GRCh37 8 74204984 74204984 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 78 98 0 ENST00000352983.2:c.63G>A p.Lys21= p.K21= ENST00000352983 21 aaG/aaA 0 +RPS16 UCSF GRCh37 19 39924353 39924353 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 15 60 0 ENST00000251453.3:c.199G>A p.Asp67Asn p.D67N ENST00000251453 NM_001020.4 67 Gac/Aac 0 +RPS27A UCSF GRCh37 2 55462702 55462702 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 117 16 122 0 ENST00000272317.6:c.460G>A p.Glu154Lys p.E154K ENST00000272317 NM_002954.5 154 Gaa/Aaa 0 +RRP12 UCSF GRCh37 10 99141531 99141531 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 12 15 0 ENST00000370992.4:c.1261G>A p.Val421Met p.V421M ENST00000370992 NM_015179.3 421 Gtg/Atg 0 +RRP8 UCSF GRCh37 11 6622723 6622723 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 27 27 0 ENST00000254605.6:c.573G>A p.Arg191= p.R191= ENST00000254605 NM_015324.3 191 cgG/cgA 0 +RS1 UCSF GRCh37 X 18674867 18674867 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 8 26 35 0 ENST00000379984.3:c.90G>A p.Glu30= p.E30= ENST00000379984 NM_000330.3 30 gaG/gaA 0 +RSAD1 UCSF GRCh37 17 48559607 48559607 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 5 14 0 ENST00000258955.2:c.630G>A p.Gly210= p.G210= ENST00000258955 NM_018346.1 210 ggG/ggA 0 +RTN4IP1 UCSF GRCh37 6 107035715 107035715 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 20 59 0 ENST00000369063.3:c.829G>A p.Val277Ile p.V277I ENST00000369063 NM_032730.4 277 Gtt/Att 0 +RXRB UCSF GRCh37 6 33162485 33162485 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 5 22 0 ENST00000374685.4:c.1588C>T p.Leu530Phe p.L530F ENST00000374685 530 Ctt/Ttt 0 +RYK UCSF GRCh37 3 133894806 133894806 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 25 99 0 ENST00000296084.4:c.1386C>T p.Val462= p.V462= ENST00000296084 NM_001005861.2 462 gtC/gtT 0 +RYR3 UCSF GRCh37 15 34015071 34015071 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 121 16 84 0 ENST00000389232.4:c.6775C>T p.Pro2259Ser p.P2259S ENST00000389232 NM_001036.3 2259 Ccc/Tcc 0 +S100A7A UCSF GRCh37 1 153390636 153390636 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 26 63 0 ENST00000368729.4:c.78G>A p.Lys26= p.K26= ENST00000368729 NM_176823.3 26 aaG/aaA 0 +S1PR4 UCSF GRCh37 19 3179754 3179754 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 7 19 0 ENST00000246115.3:c.964C>T p.Leu322Phe p.L322F ENST00000246115 NM_003775.3 322 Ctc/Ttc 0 +SAG UCSF GRCh37 2 234229373 234229373 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 10 22 0 ENST00000409110.1:c.279G>A p.Gln93= p.Q93= ENST00000409110 NM_000541.4 93 caG/caA 0 +SART3 UCSF GRCh37 12 108930558 108930558 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 21 41 0 ENST00000228284.3:c.1313C>T p.Ser438Phe p.S438F ENST00000228284 NM_014706.3 438 tCc/tTc 0 +SATL1 UCSF GRCh37 X 84362618 84362618 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 7 22 0 ENST00000509231.1:c.1357C>T p.Gln453Ter p.Q453* ENST00000509231 453 Caa/Taa 0 +SBF1 UCSF GRCh37 22 50893373 50893373 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 5 12 0 ENST00000380817.3:c.4682G>A p.Gly1561Glu p.G1561E ENST00000380817 NM_002972.2 1561 gGg/gAg 0 +SBF2 UCSF GRCh37 11 9871647 9871647 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 48 24 80 0 ENST00000256190.8:c.2729A>G p.Gln910Arg p.Q910R ENST00000256190 NM_030962.3 910 cAg/cGg 0 +SCAF4 UCSF GRCh37 21 33068918 33068918 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 18 4 23 0 ENST00000286835.7:c.923C>T p.Pro308Leu p.P308L ENST00000286835 NM_020706.2 308 cCc/cTc 0 +SCAMP4 UCSF GRCh37 19 1918968 1918968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 23 27 0 ENST00000316097.8:c.374G>A p.Gly125Asp p.G125D ENST00000316097 NM_079834.2 125 gGc/gAc 0 +SCAPER UCSF GRCh37 15 77092596 77092596 + missense_variant Missense_Mutation SNP T T G NOVEL P01_Rec Untested WXS Illumina HiSeq 75 60 120 0 ENST00000563290.1:c.604A>C p.Asn202His p.N202H ENST00000563290 202 Aat/Cat 0 +SCARA3 UCSF GRCh37 8 27528549 27528549 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 3 21 0 ENST00000301904.3:c.1502C>T p.Pro501Leu p.P501L ENST00000301904 NM_016240.2 501 cCt/cTt 0 +SCARB1 UCSF GRCh37 12 125298883 125298883 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 3 47 31 0 ENST00000261693.6:c.495C>T p.Thr165= p.T165= ENST00000261693 NM_005505.4 165 acC/acT 0 +SCD UCSF GRCh37 10 102112124 102112124 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 17 56 0 ENST00000370355.2:c.312G>A p.Gly104= p.G104= ENST00000370355 NM_005063.4 104 ggG/ggA 0 +SCN11A UCSF GRCh37 3 38888991 38888991 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 23 59 0 ENST00000302328.3:c.4570C>T p.Pro1524Ser p.P1524S ENST00000302328 NM_014139.2 1524 Cca/Tca 0 +SCN1A UCSF GRCh37 2 166895998 166895998 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 15 82 0 ENST00000303395.4:c.2524C>T p.Leu842Phe p.L842F ENST00000303395 842 Ctt/Ttt 0 +SCN2A UCSF GRCh37 2 166165874 166165874 + intron_variant Intron SNP G G A snp132_rs2228983 P01_Rec Untested WXS Illumina HiSeq 69 44 97 0 ENST00000357398.3:c.697+108G>A *233* ENST00000357398 0 +SCN4A UCSF GRCh37 17 62021109 62021109 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 8 46 0 ENST00000435607.1:c.4014C>T p.Pro1338= p.P1338= ENST00000435607 NM_000334.4 1338 ccC/ccT 0 +SCNN1B UCSF GRCh37 16 23392077 23392077 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 25 16 0 ENST00000343070.2:c.1878G>A p.Gln626= p.Q626= ENST00000343070 NM_000336.2 626 caG/caA 0 +SEC11C UCSF GRCh37 18 56819825 56819825 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 113 30 133 0 ENST00000587834.1:c.255G>A p.Arg85= p.R85= ENST00000587834 NM_033280.2 85 cgG/cgA 0 +SEC23B UCSF GRCh37 20 18508219 18508219 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 182 37 180 0 ENST00000336714.3:c.1073G>A p.Gly358Glu p.G358E ENST00000336714 NM_032985.4 358 gGa/gAa 0 +SEC23B UCSF GRCh37 20 18522964 18522964 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 124 15 110 0 ENST00000336714.3:c.1429G>A p.Gly477Ser p.G477S ENST00000336714 NM_032985.4 477 Ggc/Agc 0 +SEC24B UCSF GRCh37 4 110402884 110402884 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 72 48 84 0 ENST00000265175.5:c.1112C>T p.Pro371Leu p.P371L ENST00000265175 NM_006323.2 371 cCc/cTc 0 +SEL1L3 UCSF GRCh37 4 25849177 25849177 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 74 61 98 0 ENST00000399878.3:c.472G>A p.Asp158Asn p.D158N ENST00000399878 NM_015187.3 158 Gat/Aat 0 +SELE UCSF GRCh37 1 169702801 169702801 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 12 64 0 ENST00000333360.7:c.-48G>A p.X16_splice ENST00000333360 NM_000450.2 0 +SELE UCSF GRCh37 1 169702111 169702111 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 36 58 0 ENST00000333360.7:c.66G>A p.Trp22Ter p.W22* ENST00000333360 NM_000450.2 22 tgG/tgA 0 +SELRC1 UCSF GRCh37 1 53158423 53158423 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 10 47 0 ENST00000371538.3:c.223G>A p.Gly75Arg p.G75R ENST00000371538 NM_023077.2 75 Ggg/Agg 0 +SEMA3D UCSF GRCh37 7 84628924 84628924 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 31 55 0 ENST00000284136.6:c.2166C>T p.Ser722= p.S722= ENST00000284136 NM_152754.2 722 agC/agT 0 +SERINC2 UCSF GRCh37 1 31899568 31899568 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 11 38 0 ENST00000373710.1:c.705C>T p.Tyr235= p.Y235= ENST00000373710 NM_001199038.1 235 taC/taT 0 +SERPINA6 UCSF GRCh37 14 94772555 94772555 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 6 21 0 ENST00000341584.3:c.885C>T p.Ser295= p.S295= ENST00000341584 NM_001756.3 295 agC/agT 0 +SERPINE1 UCSF GRCh37 7 100773852 100773852 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 102 64 105 0 ENST00000223095.4:c.422G>A p.Arg141Gln p.R141Q ENST00000223095 NM_000602.4 141 cGg/cAg 0 +SERPINE2 UCSF GRCh37 2 224866420 224866420 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 18 27 0 ENST00000447280.2:c.234G>A p.Gln78= p.Q78= ENST00000447280 NM_001136530.1 78 caG/caA 0 +SERPINF1 UCSF GRCh37 17 1679946 1679946 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 20 52 0 ENST00000254722.4:c.907C>T p.Arg303Ter p.R303* ENST00000254722 NM_002615.5 303 Cga/Tga 0 +SERPING1 UCSF GRCh37 11 57367484 57367484 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 9 55 0 ENST00000278407.4:c.184G>A p.Val62Ile p.V62I ENST00000278407 NM_000062.2 62 Gtt/Att 0 +SESN3 UCSF GRCh37 11 94911935 94911935 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 42 91 0 ENST00000536441.1:c.995G>A p.Gly332Asp p.G332D ENST00000536441 NM_144665.3 332 gGt/gAt 0 +SETD1A UCSF GRCh37 16 30977082 30977082 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 7 9 0 ENST00000262519.8:c.1880C>T p.Pro627Leu p.P627L ENST00000262519 NM_014712.1 627 cCc/cTc 0 +SETD2 UCSF GRCh37 3 47098404 47098404 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 36 4 45 0 ENST00000409792.3:c.6870G>A p.Gln2290= p.Q2290= ENST00000409792 NM_014159.6 2290 caG/caA 0 +SETD5 UCSF GRCh37 3 9483374 9483374 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 86 59 142 0 ENST00000402198.1:c.908G>A p.Gly303Glu p.G303E ENST00000402198 NM_001080517.1 303 gGg/gAg 0 +SEZ6 UCSF GRCh37 17 27296849 27296849 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 4 15 0 ENST00000317338.12:c.980C>T p.Thr327Ile p.T327I ENST00000317338 327 aCc/aTc 0 +SEZ6 UCSF GRCh37 17 27284412 27284412 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 31 77 0 ENST00000317338.12:c.2448C>T p.Arg816= p.R816= ENST00000317338 816 cgC/cgT 0 +SFSWAP UCSF GRCh37 12 132210037 132210037 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 14 56 0 ENST00000541286.1:c.694G>A p.Ala232Thr p.A232T ENST00000541286 NM_001261411.1 232 Gcc/Acc 0 +SFTPD UCSF GRCh37 10 81702620 81702620 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 13 33 0 ENST00000372292.3:c.215C>T p.Ala72Val p.A72V ENST00000372292 NM_003019.4 72 gCa/gTa 0 +SFXN5 UCSF GRCh37 2 73215423 73215423 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 16 8 16 0 ENST00000272433.2:c.589C>T p.Leu197Phe p.L197F ENST00000272433 NM_144579.2 197 Ctt/Ttt 0 +SGIP1 UCSF GRCh37 1 67142712 67142712 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 26 59 0 ENST00000371037.4:c.672G>A p.Trp224Ter p.W224* ENST00000371037 NM_032291.2 224 tgG/tgA 0 +SGK1 UCSF GRCh37 6 134493417 134493417 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 89 21 114 0 ENST00000367858.5:c.985G>A p.Gly329Arg p.G329R ENST00000367858 NM_001143676.1 329 Gga/Aga 0 +SGK223 UCSF GRCh37 8 8235518 8235518 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 16 29 0 ENST00000520004.1:c.401G>A p.Gly134Asp p.G134D ENST00000520004 134 gGc/gAc 0 +SH3D21 UCSF GRCh37 1 36786324 36786324 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 28 15 35 0 ENST00000453908.2:c.2060G>A p.Gly687Glu p.G687E ENST00000453908 NM_001162530.1 687 gGa/gAa 0 +SH3PXD2A UCSF GRCh37 10 105386875 105386875 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 9 30 0 ENST00000355946.2:c.689C>T p.Ser230Phe p.S230F ENST00000355946 NM_014631.2 230 tCc/tTc 0 +SH3PXD2A UCSF GRCh37 10 105561100 105561100 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 28 0 ENST00000355946.2:c.93C>T p.Thr31= p.T31= ENST00000355946 NM_014631.2 31 acC/acT 0 +SH3RF2 UCSF GRCh37 5 145379823 145379823 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 18 5 21 0 ENST00000511217.1:c.581C>T p.Ala194Val p.A194V ENST00000511217 194 gCc/gTc 0 +SH3TC1 UCSF GRCh37 4 8221106 8221106 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 13 0 ENST00000245105.3:c.961C>T p.Pro321Ser p.P321S ENST00000245105 NM_018986.3 321 Ccc/Tcc 0 +SHANK2 UCSF GRCh37 11 70332216 70332216 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 6 31 0 ENST00000338508.4:c.4185C>T p.Pro1395= p.P1395= ENST00000338508 1395 ccC/ccT 0 +SIM1 UCSF GRCh37 6 100911214 100911214 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 30 59 0 ENST00000369208.3:c.131G>A p.Arg44Lys p.R44K ENST00000369208 44 aGa/aAa 0 +SIRPB1 UCSF GRCh37 20 1552408 1552408 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 10 39 0 ENST00000381605.4:c.709G>A p.Asp237Asn p.D237N ENST00000381605 NM_006065.3 237 Gac/Aac 0 +SLAMF6 UCSF GRCh37 1 160458953 160458953 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 63 7 38 0 ENST00000368057.3:c.804C>T p.Ser268= p.S268= ENST00000368057 268 tcC/tcT 0 +SLC12A6 UCSF GRCh37 15 34526102 34526102 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 16 47 0 ENST00000354181.3:c.3433G>A p.Val1145Met p.V1145M ENST00000354181 1145 Gtg/Atg 0 +SLC15A3 UCSF GRCh37 11 60708694 60708694 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 7 15 0 ENST00000227880.3:c.1176C>T p.Arg392= p.R392= ENST00000227880 NM_016582.2 392 cgC/cgT 0 +SLC1A5 UCSF GRCh37 19 47280365 47280365 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 5 20 22 0 ENST00000542575.2:c.1255G>A p.Val419Ile p.V419I ENST00000542575 NM_005628.2 419 Gtc/Atc 0 +SLC1A6 UCSF GRCh37 19 15061096 15061096 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 18 6 19 0 ENST00000221742.3:c.1606C>T p.Leu536Phe p.L536F ENST00000221742 NM_005071.2 536 Ctc/Ttc 0 +SLC22A16 UCSF GRCh37 6 110746096 110746096 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 90 55 115 0 ENST00000368919.3:c.1714G>A p.Asp572Asn p.D572N ENST00000368919 NM_033125.3 572 Gat/Aat 0 +SLC22A20 UCSF GRCh37 11 64985117 64985117 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 9 19 0 ENST00000525264.1:n.622G>A *208* ENST00000525264 0 +SLC24A1 UCSF GRCh37 15 65916651 65916651 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 49 72 0 ENST00000261892.6:c.233G>A p.Ser78Asn p.S78N ENST00000261892 NM_004727.2 78 aGc/aAc 0 +SLC25A37 UCSF GRCh37 8 23429182 23429182 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.008,1000g2011may_all_0.0299,snp132_rs34146184 P01_Rec Untested WXS Illumina HiSeq 55 12 53 0 ENST00000519973.1:c.831C>T p.Gly277= p.G277= ENST00000519973 NM_016612.2 277 ggC/ggT 0 +SLC26A2 UCSF GRCh37 5 149357685 149357685 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 21 88 0 ENST00000286298.4:c.470C>T p.Ser157Phe p.S157F ENST00000286298 NM_000112.3 157 tCc/tTc 0 +SLC26A8 UCSF GRCh37 6 35912088 35912088 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 94 40 80 0 ENST00000490799.1:c.2502C>T p.Ser834= p.S834= ENST00000490799 NM_052961.3 834 agC/agT 0 +SLC27A6 UCSF GRCh37 5 128351585 128351585 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 35 91 0 ENST00000262462.4:c.977G>A p.Gly326Glu p.G326E ENST00000262462 326 gGa/gAa 0 +SLC28A2 UCSF GRCh37 15 45556211 45556211 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 10 70 0 ENST00000347644.3:c.579C>T p.His193= p.H193= ENST00000347644 NM_004212.3 193 caC/caT 0 +SLC2A12 UCSF GRCh37 6 134350161 134350161 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 63 34 126 0 ENST00000275230.5:c.802C>T p.Leu268= p.L268= ENST00000275230 NM_145176.2 268 Ctg/Ttg 0 +SLC2A4 UCSF GRCh37 17 7186928 7186928 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 22 49 0 ENST00000317370.8:c.287C>T p.Ser96Phe p.S96F ENST00000317370 NM_001042.2 96 tCc/tTc 0 +SLC30A1 UCSF GRCh37 1 211749417 211749417 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 121 21 121 0 ENST00000367001.4:c.837G>A p.Gly279= p.G279= ENST00000367001 NM_021194.2 279 ggG/ggA 0 +SLC30A3 UCSF GRCh37 2 27479746 27479746 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 11 8 15 0 ENST00000233535.4:c.793G>A p.Ala265Thr p.A265T ENST00000233535 NM_003459.4 265 Gcc/Acc 0 +SLC30A5 UCSF GRCh37 5 68425286 68425286 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 9 86 0 ENST00000396591.3:c.2140C>T p.Leu714Phe p.L714F ENST00000396591 NM_022902.4 714 Ctt/Ttt 0 +SLC30A8 UCSF GRCh37 8 118175722 118175722 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 66 0 ENST00000456015.2:c.782C>T p.Ala261Val p.A261V ENST00000456015 NM_173851.2 261 gCc/gTc 0 +SLC34A3 UCSF GRCh37 9 140127052 140127052 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 4 9 0 ENST00000538474.1:c.201C>T p.Arg67= p.R67= ENST00000538474 NM_001177317.1 67 cgC/cgT 0 +SLC35F5 UCSF GRCh37 2 114512853 114512853 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 72 10 87 0 ENST00000245680.2:c.162C>T p.Asn54= p.N54= ENST00000245680 NM_025181.2 54 aaC/aaT 0 +SLC38A9 UCSF GRCh37 5 54948412 54948412 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 27 67 0 ENST00000396865.2:c.897C>T p.Leu299= p.L299= ENST00000396865 NM_173514.3 299 ctC/ctT 0 +SLC39A4 UCSF GRCh37 8 145637955 145637955 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 8 32 0 ENST00000301305.3:c.1911G>A p.Leu637= p.L637= ENST00000301305 NM_130849.3 637 ctG/ctA 0 +SLC39A6 UCSF GRCh37 18 33704519 33704519 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 30 74 0 ENST00000269187.5:c.934G>A p.Ala312Thr p.A312T ENST00000269187 NM_012319.3 312 Gct/Act 0 +SLC44A5 UCSF GRCh37 1 75693542 75693542 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 17 72 0 ENST00000370855.5:c.854G>A p.Gly285Glu p.G285E ENST00000370855 NM_152697.4 285 gGa/gAa 0 +SLC4A5 UCSF GRCh37 2 74459741 74459741 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 12 24 0 ENST00000377634.4:c.2629G>A p.Val877Met p.V877M ENST00000377634 877 Gtg/Atg 0 +SLC4A8 UCSF GRCh37 12 51855017 51855017 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 7 49 0 ENST00000453097.2:c.1043G>A p.Gly348Glu p.G348E ENST00000453097 NM_001039960.2 348 gGg/gAg 0 +SLC5A9 UCSF GRCh37 1 48701422 48701422 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 7 19 0 ENST00000236495.5:c.1238C>T p.Ala413Val p.A413V ENST00000236495 NM_001135181.1 413 gCc/gTc 0 +SLC6A12 UCSF GRCh37 12 309904 309904 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 44 43 0 ENST00000428720.1:c.624C>T p.Ser208= p.S208= ENST00000428720 NM_001122848.2 208 tcC/tcT 0 +SLC7A8 UCSF GRCh37 14 23635544 23635544 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 80 12 72 0 ENST00000316902.7:c.356+1G>A p.X119_splice ENST00000316902 NM_012244.3 0 +SLC9A10 UCSF GRCh37 3 111981803 111981803 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 34 95 0 ENST00000305815.5:c.1165C>T p.Leu389Phe p.L389F ENST00000305815 NM_183061.1 389 Ctt/Ttt 0 +SLC9A11 UCSF GRCh37 1 173517646 173517646 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 13 64 0 ENST00000367714.3:c.1343C>T p.Ala448Val p.A448V ENST00000367714 NM_178527.3 448 gCc/gTc 0 +SLC9A5 UCSF GRCh37 16 67291332 67291332 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 24 51 0 ENST00000299798.11:c.1420G>A p.Glu474Lys p.E474K ENST00000299798 NM_004594.2 474 Gaa/Aaa 0 +SLCO5A1 UCSF GRCh37 8 70650373 70650373 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 24 64 0 ENST00000260126.4:c.1325C>T p.Thr442Ile p.T442I ENST00000260126 NM_030958.2 442 aCa/aTa 0 +SLITRK5 UCSF GRCh37 13 88330363 88330363 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 12 58 0 ENST00000325089.6:c.2720G>A p.Gly907Glu p.G907E ENST00000325089 NM_015567.1 907 gGg/gAg 0 +SLMAP UCSF GRCh37 3 57846543 57846543 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 19 45 0 ENST00000295951.3:c.805G>A p.Val269Ile p.V269I ENST00000295951 269 Gtt/Att 0 +SLMO2 UCSF GRCh37 20 57613588 57613588 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 32 68 0 ENST00000355937.4:c.134C>T p.Pro45Leu p.P45L ENST00000355937 NM_016045.2 45 cCc/cTc 0 +SMAP1 UCSF GRCh37 6 71508401 71508401 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 19 85 0 ENST00000370455.3:c.537G>A p.Lys179= p.K179= ENST00000370455 NM_001281440.1 179 aaG/aaA 0 +SMARCA2 UCSF GRCh37 9 2039702 2039702 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 7 11 25 0 ENST00000382203.1:c.592C>T p.Leu198Phe p.L198F ENST00000382203 198 Ctc/Ttc 0 +SMARCC2 UCSF GRCh37 12 56567624 56567624 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 51 67 0 ENST00000267064.4:c.1506C>T p.Ala502= p.A502= ENST00000267064 NM_003075.3 502 gcC/gcT 0 +SMARCD1 UCSF GRCh37 12 50484110 50484110 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 15 62 0 ENST00000394963.4:c.960G>A p.Trp320Ter p.W320* ENST00000394963 NM_003076.4 320 tgG/tgA 0 +SMC6 UCSF GRCh37 2 17897360 17897360 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 47 108 0 ENST00000448223.2:c.1518C>T p.Gly506= p.G506= ENST00000448223 NM_001142286.1 506 ggC/ggT 0 +SMC6 UCSF GRCh37 2 17897456 17897456 + synonymous_variant Silent SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 49 56 109 0 ENST00000448223.2:c.1422T>C p.Thr474= p.T474= ENST00000448223 NM_001142286.1 474 acT/acC 0 +SMCHD1 UCSF GRCh37 18 2697853 2697853 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 14 76 0 ENST00000320876.6:c.1156G>A p.Val386Ile p.V386I ENST00000320876 NM_015295.2 386 Gta/Ata 0 +SMEK2 UCSF GRCh37 2 55825776 55825776 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 44 115 0 ENST00000345102.5:c.697G>A p.Ala233Thr p.A233T ENST00000345102 NM_001122964.1 233 Gct/Act 0 +SMG7 UCSF GRCh37 1 183515267 183515267 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P01_Rec Untested WXS Illumina HiSeq 7 0 ENST00000507469.1:c.2407del p.Met803Ter p.M803* ENST00000507469 NM_201569.2 800 gAa/ga 0 +SMURF1 UCSF GRCh37 7 98649907 98649907 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 52 11 38 0 ENST00000361125.1:c.642C>T p.Asn214= p.N214= ENST00000361125 NM_020429.2 214 aaC/aaT 0 +SMURF2 UCSF GRCh37 17 62559045 62559045 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 40 28 56 0 ENST00000262435.9:c.1056G>A p.Val352= p.V352= ENST00000262435 NM_022739.3 352 gtG/gtA 0 +SNAP47 UCSF GRCh37 1 227935657 227935657 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 7 40 0 ENST00000366759.4:c.355G>A p.Gly119Ser p.G119S ENST00000366759 NM_053052.3 119 Ggc/Agc 0 +SND1 UCSF GRCh37 7 127447556 127447556 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 68 16 76 0 ENST00000354725.3:c.1171C>T p.Arg391Cys p.R391C ENST00000354725 NM_014390.2 391 Cgt/Tgt 0 +SNRPA UCSF GRCh37 19 41268881 41268881 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 4 17 0 ENST00000243563.3:c.502G>A p.Gly168Ser p.G168S ENST00000243563 NM_004596.4 168 Ggt/Agt 0 +SNX4 UCSF GRCh37 3 125223584 125223584 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 8 23 64 0 ENST00000251775.4:c.146C>T p.Thr49Ile p.T49I ENST00000251775 NM_003794.3 49 aCa/aTa 0 +SNX4 UCSF GRCh37 3 125179650 125179650 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 4 55 0 ENST00000251775.4:c.909G>A p.Gln303= p.Q303= ENST00000251775 NM_003794.3 303 caG/caA 0 +SON UCSF GRCh37 21 34932013 34932013 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 93 15 146 0 ENST00000356577.4:c.6589C>T p.Pro2197Ser p.P2197S ENST00000356577 NM_138927.2 2197 Cct/Tct 0 +SORBS3 UCSF GRCh37 8 22424195 22424195 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 7 13 0 ENST00000240123.7:c.1112G>A p.Gly371Glu p.G371E ENST00000240123 NM_005775.4 371 gGg/gAg 0 +SOS2 UCSF GRCh37 14 50597331 50597331 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 15 82 0 ENST00000216373.5:c.3225G>A p.Glu1075= p.E1075= ENST00000216373 NM_006939.2 1075 gaG/gaA 0 +SOX13 UCSF GRCh37 1 204082180 204082180 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 3 10 0 ENST00000367204.1:c.137C>T p.Pro46Leu p.P46L ENST00000367204 NM_005686.2 46 cCt/cTt 0 +SP140 UCSF GRCh37 2 231101935 231101935 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 35 0 ENST00000392045.3:c.197G>A p.Gly66Asp p.G66D ENST00000392045 NM_007237.4 66 gGc/gAc 0 +SPACA7 UCSF GRCh37 13 113053461 113053461 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 19 65 0 ENST00000283550.3:c.323G>A p.Gly108Asp p.G108D ENST00000283550 NM_145248.4 108 gGc/gAc 0 +SPAG1 UCSF GRCh37 8 101232598 101232598 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 50 106 0 ENST00000388798.2:c.1627G>A p.Asp543Asn p.D543N ENST00000388798 NM_003114.4 543 Gat/Aat 0 +SPAG11B UCSF GRCh37 8 7320246 7320246 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 43 15 95 0 ENST00000398462.2:c.197G>A p.Arg66His p.R66H ENST00000398462 NM_058201.2 66 cGc/cAc 0 +SPAG9 UCSF GRCh37 17 49068013 49068013 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 16 47 0 ENST00000262013.7:c.2415C>T p.Asp805= p.D805= ENST00000262013 NM_001130528.2 805 gaC/gaT 0 +SPANXN4 UCSF GRCh37 X 142121991 142121991 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 11 35 0 ENST00000446864.1:c.259G>A p.Asp87Asn p.D87N ENST00000446864 NM_001009613.2 87 Gac/Aac 0 +SPATA20 UCSF GRCh37 17 48627611 48627611 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 6 36 0 ENST00000006658.6:c.1036C>T p.His346Tyr p.H346Y ENST00000006658 NM_022827.3 346 Cac/Tac 0 +SPATA6 UCSF GRCh37 1 48865249 48865249 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 87 30 87 0 ENST00000371847.3:c.554G>A p.Arg185Lys p.R185K ENST00000371847 NM_019073.2 185 aGa/aAa 0 +SPDYE4 UCSF GRCh37 17 8656648 8656648 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 13 20 0 ENST00000328794.6:c.645G>A p.Glu215= p.E215= ENST00000328794 NM_001128076.1 215 gaG/gaA 0 +SPEF2 UCSF GRCh37 5 35759703 35759703 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 129 18 137 0 ENST00000356031.3:c.3502C>T p.Leu1168Phe p.L1168F ENST00000356031 NM_024867.3 1168 Ctc/Ttc 0 +SPEG UCSF GRCh37 2 220338590 220338590 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 12 19 0 ENST00000312358.7:c.4412G>A p.Gly1471Asp p.G1471D ENST00000312358 NM_005876.4 1471 gGc/gAc 0 +SPHKAP UCSF GRCh37 2 228884573 228884573 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 155 23 141 0 ENST00000392056.3:c.997G>A p.Glu333Lys p.E333K ENST00000392056 NM_001142644.1 333 Gaa/Aaa 0 +SPHKAP UCSF GRCh37 2 228855860 228855860 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 12 50 0 ENST00000392056.3:c.4815G>A p.Gln1605= p.Q1605= ENST00000392056 NM_001142644.1 1605 caG/caA 0 +SPO11 UCSF GRCh37 20 55909861 55909861 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 20 41 0 ENST00000371263.3:c.566G>A p.Gly189Asp p.G189D ENST00000371263 NM_012444.2 189 gGc/gAc 0 +SPTA1 UCSF GRCh37 1 158639310 158639310 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 76 66 105 0 ENST00000368147.4:c.1721G>A p.Arg574Lys p.R574K ENST00000368147 NM_003126.2 574 aGa/aAa 0 +SPTA1 UCSF GRCh37 1 158655131 158655131 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 67 11 69 0 ENST00000368147.4:c.31G>A p.Glu11Lys p.E11K ENST00000368147 NM_003126.2 11 Gag/Aag 0 +SPTAN1 UCSF GRCh37 9 131337077 131337077 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 75 27 56 0 ENST00000372739.3:c.487G>A p.Asp163Asn p.D163N ENST00000372739 NM_001130438.2 163 Gac/Aac 0 +SPTAN1 UCSF GRCh37 9 131337540 131337540 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 91 33 91 0 ENST00000372739.3:c.567G>A p.Lys189= p.K189= ENST00000372739 NM_001130438.2 189 aaG/aaA 0 +SRCIN1 UCSF GRCh37 17 36708983 36708983 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 28 29 50 0 ENST00000264659.7:c.2310G>A p.Gly770= p.G770= ENST00000264659 NM_025248.2 770 ggG/ggA 0 +SRD5A2 UCSF GRCh37 2 31758811 31758811 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 28 48 0 ENST00000405650.1:n.473C>T *158* ENST00000405650 0 +SRRM2 UCSF GRCh37 16 2817289 2817289 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 10 31 0 ENST00000301740.8:c.6760G>A p.Val2254Met p.V2254M ENST00000301740 NM_016333.3 2254 Gtg/Atg 0 +SRRM2 UCSF GRCh37 16 2807494 2807494 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 44 25 59 0 ENST00000301740.8:c.264G>A p.Gln88= p.Q88= ENST00000301740 NM_016333.3 88 caG/caA 0 +SRRT UCSF GRCh37 7 100482407 100482407 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 9 25 0 ENST00000347433.4:c.989G>A p.Gly330Asp p.G330D ENST00000347433 330 gGt/gAt 0 +SRSF1 UCSF GRCh37 17 56082832 56082832 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 92 19 70 0 ENST00000258962.4:c.682C>T p.Pro228Ser p.P228S ENST00000258962 NM_006924.4 228 Cca/Tca 0 +SS18 UCSF GRCh37 18 23658055 23658055 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 15 66 0 ENST00000415083.2:c.216G>A p.Gln72= p.Q72= ENST00000415083 NM_001007559.1 72 caG/caA 0 +SSH2 UCSF GRCh37 17 28004719 28004719 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 30 72 0 ENST00000269033.3:c.439G>A p.Asp147Asn p.D147N ENST00000269033 NM_033389.2 147 Gac/Aac 0 +SSPO UCSF GRCh37 7 149484482 149484482 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 9 41 0 ENST00000378016.2:n.3405C>T *1135* ENST00000378016 0 +SSTR2 UCSF GRCh37 17 71166313 71166313 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 85 11 47 0 ENST00000357585.2:c.855C>T p.Ser285= p.S285= ENST00000357585 NM_001050.2 285 agC/agT 0 +SSX1 UCSF GRCh37 X 48123289 48123289 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 22 72 0 ENST00000376919.3:c.403G>A p.Asp135Asn p.D135N ENST00000376919 NM_005635.3 135 Gat/Aat 0 +ST18 UCSF GRCh37 8 53028885 53028885 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 25 50 0 ENST00000276480.7:c.2953C>T p.Leu985= p.L985= ENST00000276480 NM_014682.2 985 Cta/Tta 0 +ST3GAL5 UCSF GRCh37 2 86090527 86090527 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 41 47 0 ENST00000377332.3:c.164G>A p.Ser55Asn p.S55N ENST00000377332 NM_003896.3 55 aGc/aAc 0 +ST8SIA1 UCSF GRCh37 12 22440198 22440198 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 7 53 0 ENST00000396037.4:c.266C>T p.Ala89Val p.A89V ENST00000396037 NM_003034.3 89 gCc/gTc 0 +STAG1 UCSF GRCh37 3 136341997 136341997 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 24 125 0 ENST00000383202.2:c.123C>T p.Gly41= p.G41= ENST00000383202 NM_005862.2 41 ggC/ggT 0 +STAG3 UCSF GRCh37 7 99808690 99808690 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 12 23 0 ENST00000426455.1:c.3295C>T p.Leu1099= p.L1099= ENST00000426455 NM_001282716.1 1099 Ctg/Ttg 0 +STARD13 UCSF GRCh37 13 33686902 33686902 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 110 17 94 0 ENST00000336934.5:c.2448C>T p.Pro816= p.P816= ENST00000336934 NM_178006.3 816 ccC/ccT 0 +STAT5A UCSF GRCh37 17 40447808 40447808 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 5 21 0 ENST00000345506.4:c.547C>T p.Gln183Ter p.Q183* ENST00000345506 NM_003152.3 183 Caa/Taa 0 +STC2 UCSF GRCh37 5 172744859 172744859 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 63 12 85 0 ENST00000265087.4:c.900C>T p.Ile300= p.I300= ENST00000265087 NM_003714.2 300 atC/atT 0 +STEAP1 UCSF GRCh37 7 89790512 89790512 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 120 15 121 0 ENST00000297205.2:c.478A>G p.Thr160Ala p.T160A ENST00000297205 NM_012449.2 160 Aca/Gca 0 +STIL UCSF GRCh37 1 47767251 47767251 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 30 73 0 ENST00000371877.3:c.435C>T p.Asp145= p.D145= ENST00000371877 145 gaC/gaT 0 +STIM1 UCSF GRCh37 11 4091387 4091387 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 27 41 0 ENST00000300737.4:c.745G>A p.Glu249Lys p.E249K ENST00000300737 NM_003156.3 249 Gag/Aag 0 +STK17B UCSF GRCh37 2 197021289 197021289 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 41 78 0 ENST00000263955.4:c.209G>A p.Gly70Glu p.G70E ENST00000263955 NM_004226.3 70 gGa/gAa 0 +STK35 UCSF GRCh37 20 2083970 2083970 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 9 6 14 0 ENST00000381482.3:c.851G>A p.Ser284Asn p.S284N ENST00000381482 284 aGc/aAc 0 +STMN3 UCSF GRCh37 20 62275234 62275234 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 4 15 21 0 ENST00000370053.1:c.166G>A p.Val56Ile p.V56I ENST00000370053 NM_015894.3 56 Gtc/Atc 0 +STXBP5 UCSF GRCh37 6 147685202 147685202 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 111 21 121 0 ENST00000321680.6:c.2981G>A p.Arg994Lys p.R994K ENST00000321680 NM_001127715.2 994 aGa/aAa 0 +SUGP1 UCSF GRCh37 19 19420913 19420913 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 18 36 0 ENST00000247001.5:c.303C>T p.Thr101= p.T101= ENST00000247001 NM_172231.3 101 acC/acT 0 +SULT1A2 UCSF GRCh37 16 28603601 28603601 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 11 49 0 ENST00000395630.1:c.758C>T p.Ser253Phe p.S253F ENST00000395630 NM_177528.2 253 tCc/tTc 0 +SUPT5H UCSF GRCh37 19 39949503 39949503 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 9 40 0 ENST00000599117.1:c.365C>T p.Ala122Val p.A122V ENST00000599117 122 gCt/gTt 0 +SUPT6H UCSF GRCh37 17 27008350 27008350 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 12 44 0 ENST00000314616.6:c.1426C>T p.Pro476Ser p.P476S ENST00000314616 NM_003170.3 476 Cct/Tct 0 +SWAP70 UCSF GRCh37 11 9746358 9746358 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 42 95 0 ENST00000318950.6:c.568G>A p.Gly190Ser p.G190S ENST00000318950 NM_015055.2 190 Ggc/Agc 0 +SYCE2 UCSF GRCh37 19 13010179 13010179 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 17 36 0 ENST00000293695.7:c.633G>A p.Gln211= p.Q211= ENST00000293695 NM_001105578.1 211 caG/caA 0 +SYCP1 UCSF GRCh37 1 115400096 115400096 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 15 56 0 ENST00000369522.3:c.269G>A p.Gly90Glu p.G90E ENST00000369522 NM_003176.2 90 gGa/gAa 0 +SYF2 UCSF GRCh37 1 25549922 25549922 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 134 27 115 0 ENST00000236273.4:c.567G>A p.Gln189= p.Q189= ENST00000236273 NM_015484.4 189 caG/caA 0 +SYNE2 UCSF GRCh37 14 64519153 64519153 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 15 89 0 ENST00000358025.3:c.8522C>T p.Ala2841Val p.A2841V ENST00000358025 NM_182914.2 2841 gCt/gTt 0 +SYNM UCSF GRCh37 15 99670863 99670863 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 22 44 0 ENST00000336292.6:c.2295C>T p.Val765= p.V765= ENST00000336292 NM_145728.2 765 gtC/gtT 0 +SYNPO2 UCSF GRCh37 4 119944628 119944628 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 25 69 0 ENST00000307142.4:c.149G>A p.Gly50Glu p.G50E ENST00000307142 NM_133477.2 50 gGa/gAa 0 +SYNPO2L UCSF GRCh37 10 75414027 75414027 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 3 9 0 ENST00000394810.2:c.117G>A p.Arg39= p.R39= ENST00000394810 NM_001114133.1 39 cgG/cgA 0 +SYNRG UCSF GRCh37 17 35946594 35946594 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 9 65 0 ENST00000339208.6:c.304C>T p.Leu102= p.L102= ENST00000339208 NM_001163544.1 102 Ctg/Ttg 0 +SYPL2 UCSF GRCh37 1 110022032 110022032 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 29 35 0 ENST00000369872.3:c.681C>T p.Ala227= p.A227= ENST00000369872 NM_001040709.1 227 gcC/gcT 0 +SYTL2 UCSF GRCh37 11 85447625 85447625 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 15 60 0 ENST00000316356.4:c.505C>T p.Pro169Ser p.P169S ENST00000316356 169 Cca/Tca 0 +SYVN1 UCSF GRCh37 11 64898470 64898470 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 17 40 0 ENST00000377190.3:c.862G>A p.Asp288Asn p.D288N ENST00000377190 NM_172230.2 288 Gac/Aac 0 +SYVN1 UCSF GRCh37 11 64899725 64899725 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 15 28 0 ENST00000377190.3:c.525C>T p.Gly175= p.G175= ENST00000377190 NM_172230.2 175 ggC/ggT 0 +TAB2 UCSF GRCh37 6 149699780 149699780 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 46 113 0 ENST00000367456.1:c.729C>T p.Asn243= p.N243= ENST00000367456 243 aaC/aaT 0 +TACC2 UCSF GRCh37 10 123846070 123846070 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 1 13 24 0 ENST00000369005.1:c.4055G>A p.Gly1352Asp p.G1352D ENST00000369005 NM_206862.2 1352 gGt/gAt 0 +TACC2 UCSF GRCh37 10 123903218 123903218 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 4 24 0 ENST00000369005.1:c.5831G>A p.Ser1944Asn p.S1944N ENST00000369005 NM_206862.2 1944 aGc/aAc 0 +TACR1 UCSF GRCh37 2 75347752 75347752 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 28 36 0 ENST00000305249.5:c.532G>A p.Val178Ile p.V178I ENST00000305249 NM_001058.3 178 Gtc/Atc 0 +TADA2A UCSF GRCh37 17 35802753 35802753 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 42 9 73 0 ENST00000394395.2:c.531G>A p.Glu177= p.E177= ENST00000394395 NM_001166105.1 177 gaG/gaA 0 +TAF1L UCSF GRCh37 9 32630947 32630947 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 103 56 165 0 ENST00000242310.4:c.4631C>T p.Ser1544Phe p.S1544F ENST00000242310 NM_153809.2 1544 tCt/tTt 0 +TAF3 UCSF GRCh37 10 7866448 7866448 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 88 46 126 0 ENST00000344293.5:c.334C>T p.Pro112Ser p.P112S ENST00000344293 NM_031923.3 112 Cct/Tct 0 +TAGAP UCSF GRCh37 6 159457737 159457737 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 72 11 72 0 ENST00000367066.3:c.1318C>T p.Leu440= p.L440= ENST00000367066 NM_054114.4 440 Ctg/Ttg 0 +TAOK3 UCSF GRCh37 12 118627651 118627651 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 50 103 0 ENST00000392533.3:c.1290G>A p.Arg430= p.R430= ENST00000392533 NM_016281.3 430 cgG/cgA 0 +TARBP1 UCSF GRCh37 1 234563473 234563473 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 8 56 0 ENST00000040877.1:c.3100G>A p.Gly1034Arg p.G1034R ENST00000040877 NM_005646.3 1034 Gga/Aga 0 +TAS1R1 UCSF GRCh37 1 6634898 6634898 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 12 17 0 ENST00000333172.6:c.706G>A p.Gly236Arg p.G236R ENST00000333172 NM_138697.3 236 Ggg/Agg 0 +TAS2R30 UCSF GRCh37 12 11286113 11286113 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 127 50 124 0 ENST00000539585.1:c.731C>T p.Ser244Phe p.S244F ENST00000539585 NM_001097643.1 244 tCc/tTc 0 +TAS2R31 UCSF GRCh37 12 11183443 11183443 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 93 63 154 0 ENST00000390675.2:c.492G>A p.Trp164Ter p.W164* ENST00000390675 NM_176885.2 164 tgG/tgA 0 +TAS2R60 UCSF GRCh37 7 143140762 143140762 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 40 74 0 ENST00000332690.1:c.217G>A p.Val73Ile p.V73I ENST00000332690 NM_177437.1 73 Gta/Ata 0 +TBC1D1 UCSF GRCh37 4 38134768 38134768 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 62 70 0 ENST00000261439.4:c.3196G>A p.Glu1066Lys p.E1066K ENST00000261439 NM_015173.3 1066 Gaa/Aaa 0 +TBC1D10A UCSF GRCh37 22 30691779 30691779 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 6 11 0 ENST00000403477.3:c.492C>T p.Asp164= p.D164= ENST00000403477 NM_001204240.1 164 gaC/gaT 0 +TBC1D25 UCSF GRCh37 X 48419031 48419031 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 8 48 0 ENST00000376771.4:c.1735G>A p.Val579Ile p.V579I ENST00000376771 NM_002536.2 579 Gta/Ata 0 +TBC1D30 UCSF GRCh37 12 65232609 65232609 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 81 69 85 0 ENST00000539867.1:c.910G>A p.Ala304Thr p.A304T ENST00000539867 NM_015279.1 304 Gct/Act 0 +TBCD UCSF GRCh37 17 80884302 80884302 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 59 32 62 0 ENST00000355528.4:c.2406C>T p.Thr802= p.T802= ENST00000355528 NM_005993.4 802 acC/acT 0 +TCEB3 UCSF GRCh37 1 24077496 24077496 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 45 26 54 0 ENST00000418390.2:c.479G>A p.Arg160Lys p.R160K ENST00000418390 NM_003198.2 160 aGg/aAg 0 +TCF3 UCSF GRCh37 19 1612371 1612371 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 5 19 0 ENST00000344749.5:c.1648G>A p.Ala550Thr p.A550T ENST00000344749 NM_001136139.2 550 Gcc/Acc 0 +TCF7L1 UCSF GRCh37 2 85510672 85510672 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 88 56 71 0 ENST00000282111.3:c.496G>A p.Asp166Asn p.D166N ENST00000282111 NM_031283.2 166 Gac/Aac 0 +TCN2 UCSF GRCh37 22 31018968 31018968 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 33 84 0 ENST00000215838.3:c.1120G>A p.Ala374Thr p.A374T ENST00000215838 374 Gcc/Acc 0 +TCP11 UCSF GRCh37 6 35107840 35107840 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 37 93 0 ENST00000311875.5:c.163+684C>T *55* ENST00000311875 0 +TCP11L1 UCSF GRCh37 11 33094171 33094171 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 93 20 91 0 ENST00000334274.4:c.1479C>T p.Val493= p.V493= ENST00000334274 NM_018393.3 493 gtC/gtT 0 +TDO2 UCSF GRCh37 4 156824919 156824919 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 32 77 0 ENST00000536354.2:c.9G>A p.Gly3= p.G3= ENST00000536354 NM_005651.3 3 ggG/ggA 0 +TDRD7 UCSF GRCh37 9 100245182 100245182 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 110 28 109 0 ENST00000355295.4:c.2464C>T p.Pro822Ser p.P822S ENST00000355295 NM_014290.2 822 Cct/Tct 0 +TECPR1 UCSF GRCh37 7 97862967 97862967 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 10 18 0 ENST00000447648.2:c.1438C>T p.Pro480Ser p.P480S ENST00000447648 NM_015395.2 480 Ccc/Tcc 0 +TENC1 UCSF GRCh37 12 53453653 53453653 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 10 19 0 ENST00000314276.3:c.2258G>A p.Gly753Glu p.G753E ENST00000314276 NM_015319.2 753 gGg/gAg 0 +TET2 UCSF GRCh37 4 106164085 106164085 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 48 22 60 0 ENST00000380013.4:c.3594+1G>A p.X1198_splice ENST00000380013 NM_001127208.2 0 +TET2 UCSF GRCh37 4 106157043 106157043 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 28 61 0 ENST00000380013.4:c.1944C>T p.Asp648= p.D648= ENST00000380013 NM_001127208.2 648 gaC/gaT 0 +TET2 UCSF GRCh37 4 106155153 106155153 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 18 48 0 ENST00000380013.4:c.54G>A p.Leu18= p.L18= ENST00000380013 NM_001127208.2 18 ctG/ctA 0 +TEX11 UCSF GRCh37 X 69811660 69811660 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 3 14 20 0 ENST00000395889.2:c.2126G>A p.Ser709Asn p.S709N ENST00000395889 NM_001003811.1 709 aGt/aAt 0 +TEX11 UCSF GRCh37 X 69749812 69749812 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 3 43 41 0 ENST00000395889.2:c.2603T>C p.Val868Ala p.V868A ENST00000395889 NM_001003811.1 868 gTc/gCc 0 +TFEC UCSF GRCh37 7 115596785 115596785 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 129 20 117 0 ENST00000265440.7:c.330G>A p.Gly110= p.G110= ENST00000265440 NM_012252.3 110 ggG/ggA 0 +TFIP11 UCSF GRCh37 22 26892785 26892785 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 11 53 0 ENST00000407690.1:c.1507C>T p.Pro503Ser p.P503S ENST00000407690 NM_012143.2 503 Ccg/Tcg 0 +TG UCSF GRCh37 8 134144132 134144132 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 22 110 0 ENST00000220616.4:c.7939G>A p.Glu2647Lys p.E2647K ENST00000220616 NM_003235.4 2647 Gag/Aag 0 +TGFB2 UCSF GRCh37 1 218609363 218609363 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 67 0 ENST00000366929.4:c.890C>T p.Ser297Phe p.S297F ENST00000366929 NM_001135599.2 297 tCc/tTc 0 +TGIF1 UCSF GRCh37 18 3456459 3456459 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 133 25 81 0 ENST00000330513.5:c.511C>T p.Leu171= p.L171= ENST00000330513 NM_170695.3 171 Cta/Tta 0 +TGM2 UCSF GRCh37 20 36766720 36766720 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 34 31 34 0 ENST00000361475.2:c.1410G>A p.Glu470= p.E470= ENST00000361475 NM_004613.2 470 gaG/gaA 0 +TGM7 UCSF GRCh37 15 43584920 43584920 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 50 114 0 ENST00000452443.2:c.426C>T p.Asn142= p.N142= ENST00000452443 NM_052955.2 142 aaC/aaT 0 +THSD7A UCSF GRCh37 7 11676112 11676112 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 23 39 0 ENST00000423059.4:c.667G>A p.Ala223Thr p.A223T ENST00000423059 NM_015204.2 223 Gcg/Acg 0 +THYN1 UCSF GRCh37 11 134118731 134118731 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 24 65 0 ENST00000341541.3:c.603G>A p.Gln201= p.Q201= ENST00000341541 NM_014174.2 201 caG/caA 0 +TIGD2 UCSF GRCh37 4 90034848 90034848 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 22 61 0 ENST00000317005.2:c.723C>T p.Asp241= p.D241= ENST00000317005 NM_145715.2 241 gaC/gaT 0 +TIMELESS UCSF GRCh37 12 56827356 56827357 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 0 ENST00000553532.1:c.332dup p.Leu111PhefsTer17 p.L111Ffs*17 ENST00000553532 111 ttg/tTtg 0 +TIPARP UCSF GRCh37 3 156421390 156421390 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 5 40 85 0 ENST00000461166.1:c.1425G>A p.Arg475= p.R475= ENST00000461166 NM_001184717.1 475 cgG/cgA 0 +TLN2 UCSF GRCh37 15 63076025 63076025 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 4 32 0 ENST00000561311.1:c.5672C>T p.Thr1891Ile p.T1891I ENST00000561311 1891 aCc/aTc 0 +TLR1 UCSF GRCh37 4 38799895 38799895 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 26 76 0 ENST00000308979.2:c.558C>T p.Asp186= p.D186= ENST00000308979 NM_003263.3 186 gaC/gaT 0 +TM7SF3 UCSF GRCh37 12 27128458 27128458 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 34 100 0 ENST00000343028.4:c.1421C>T p.Ala474Val p.A474V ENST00000343028 NM_016551.2 474 gCt/gTt 0 +TMC3 UCSF GRCh37 15 81648787 81648787 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 4 18 0 ENST00000359440.5:c.891+1G>A p.X297_splice ENST00000359440 NM_001080532.1 0 +TMC3 UCSF GRCh37 15 81633784 81633784 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 23 52 0 ENST00000359440.5:c.1791C>T p.Ser597= p.S597= ENST00000359440 NM_001080532.1 597 agC/agT 0 +TMEFF2 UCSF GRCh37 2 193059093 193059093 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 28 39 0 ENST00000272771.5:c.158G>A p.Gly53Asp p.G53D ENST00000272771 NM_016192.2 53 gGc/gAc 0 +TMEM106A UCSF GRCh37 17 41368603 41368603 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 68 52 77 0 ENST00000331615.3:c.565G>A p.Glu189Lys p.E189K ENST00000331615 NM_145041.1 189 Gaa/Aaa 0 +TMEM108 UCSF GRCh37 3 133114716 133114716 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 12 32 0 ENST00000321871.6:c.1614C>T p.Leu538= p.L538= ENST00000321871 NM_001136469.1 538 ctC/ctT 0 +TMEM132E UCSF GRCh37 17 32964821 32964821 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 7 18 0 ENST00000321639.5:c.2525C>T p.Ser842Phe p.S842F ENST00000321639 NM_207313.1 842 tCt/tTt 0 +TMEM173 UCSF GRCh37 5 138857072 138857072 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 5 29 0 ENST00000330794.4:c.788C>T p.Thr263Ile p.T263I ENST00000330794 NM_198282.2 263 aCc/aTc 0 +TMEM188 UCSF GRCh37 16 50063641 50063641 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 7 58 0 ENST00000458059.3:c.154C>T p.Leu52Phe p.L52F ENST00000458059 NM_153261.4 52 Ctt/Ttt 0 +TMEM196 UCSF GRCh37 7 19765226 19765226 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 27 54 0 ENST00000405764.3:c.370C>T p.Leu124Phe p.L124F ENST00000405764 NM_152774.3 124 Ctc/Ttc 0 +TMEM202 UCSF GRCh37 15 72699426 72699426 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 13 28 0 ENST00000341689.3:c.488-1G>A p.X163_splice ENST00000341689 NM_001080462.1 0 +TMEM214 UCSF GRCh37 2 27263055 27263055 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 5 48 0 ENST00000238788.9:c.1780C>T p.Leu594Phe p.L594F ENST00000238788 NM_017727.4 594 Ctc/Ttc 0 +TMEM22 UCSF GRCh37 3 136573939 136573939 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 56 94 0 ENST00000446465.2:c.637C>T p.Leu213Phe p.L213F ENST00000446465 NM_025246.2 213 Ctc/Ttc 0 +TMEM26 UCSF GRCh37 10 63195995 63195995 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 8 33 0 ENST00000399298.3:c.203C>T p.Ala68Val p.A68V ENST00000399298 NM_178505.6 68 gCc/gTc 0 +TMEM40 UCSF GRCh37 3 12791328 12791328 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 23 35 0 ENST00000314124.7:c.4G>A p.Glu2Lys p.E2K ENST00000314124 NM_018306.2 2 Gag/Aag 0 +TMEM45A UCSF GRCh37 3 100277310 100277310 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 44 82 0 ENST00000323523.4:c.465G>A p.Leu155= p.L155= ENST00000323523 NM_018004.1 155 ctG/ctA 0 +TMEM59 UCSF GRCh37 1 54502382 54502382 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 11 85 0 ENST00000234831.5:c.717G>A p.Gly239= p.G239= ENST00000234831 NM_004872.3 239 ggG/ggA 0 +TMEM72 UCSF GRCh37 10 45430347 45430347 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 40 74 0 ENST00000389583.4:c.593C>T p.Ala198Val p.A198V ENST00000389583 NM_001123376.1 198 gCc/gTc 0 +TMPRSS11E UCSF GRCh37 4 69362515 69362515 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 163 34 226 0 ENST00000305363.4:c.1265G>A p.Gly422Asp p.G422D ENST00000305363 NM_014058.3 422 gGt/gAt 0 +TMPRSS6 UCSF GRCh37 22 37462896 37462896 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 24 10 17 0 ENST00000346753.3:c.2247C>T p.Gly749= p.G749= ENST00000346753 NM_153609.2 749 ggC/ggT 0 +TMPRSS7 UCSF GRCh37 3 111793177 111793177 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 17 107 0 ENST00000419127.1:c.1323C>T p.Gly441= p.G441= ENST00000419127 NM_001042575.2 441 ggC/ggT 0 +TNC UCSF GRCh37 9 117853202 117853202 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.00296 P01_Rec Untested WXS Illumina HiSeq 49 20 47 0 ENST00000350763.4:c.96G>A p.Lys32= p.K32= ENST00000350763 NM_002160.3 32 aaG/aaA 0 +TNFRSF13C UCSF GRCh37 22 42321421 42321421 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 12 10 0 ENST00000291232.3:c.505G>A p.Gly169Ser p.G169S ENST00000291232 NM_052945.3 169 Ggc/Agc 0 +TNFRSF14 UCSF GRCh37 1 2493248 2493248 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 22 39 0 ENST00000355716.4:c.688C>T p.Pro230Ser p.P230S ENST00000355716 NM_003820.2 230 Cca/Tca 0 +TNFRSF8 UCSF GRCh37 1 12186062 12186062 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 45 6 26 0 ENST00000263932.2:c.1208C>T p.Ala403Val p.A403V ENST00000263932 NM_001243.3 403 gCc/gTc 0 +TNIK UCSF GRCh37 3 170784468 170784468 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 8 55 0 ENST00000436636.2:c.3756G>A p.Met1252Ile p.M1252I ENST00000436636 NM_015028.2 1252 atG/atA 0 +TNRC18 UCSF GRCh37 7 5399192 5399192 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 63 49 76 0 ENST00000430969.1:c.4670G>A p.Ser1557Asn p.S1557N ENST00000430969 NM_001080495.2 1557 aGc/aAc 0 +TNS1 UCSF GRCh37 2 218712366 218712366 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 27 27 0 ENST00000171887.4:c.2499G>A p.Gln833= p.Q833= ENST00000171887 NM_022648.4 833 caG/caA 0 +TNS4 UCSF GRCh37 17 38633947 38633947 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 8 23 0 ENST00000254051.6:c.2041C>T p.Pro681Ser p.P681S ENST00000254051 NM_032865.5 681 Cct/Tct 0 +TOM1 UCSF GRCh37 22 35742963 35742963 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 27 0 ENST00000411850.1:c.1325G>A p.Gly442Asp p.G442D ENST00000411850 NM_001135732.1 442 gGt/gAt 0 +TOM1L1 UCSF GRCh37 17 53016303 53016303 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 9 45 0 ENST00000575882.1:c.1052C>T p.Ser351Phe p.S351F ENST00000575882 NM_005486.2 351 tCt/tTt 0 +TOP2A UCSF GRCh37 17 38572281 38572281 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 84 10 93 0 ENST00000423485.1:c.308C>T p.Ser103Phe p.S103F ENST00000423485 NM_001067.3 103 tCt/tTt 0 +TOX UCSF GRCh37 8 59720800 59720800 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 57 15 67 0 ENST00000361421.1:c.1421C>T p.Thr474Ile p.T474I ENST00000361421 NM_014729.2 474 aCt/aTt 0 +TP53 UCSF GRCh37 17 7578527 7578527 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 8 8 15 0 ENST00000269305.4:c.403T>C p.Cys135Arg p.C135R ENST00000269305 NM_001126112.2 135 Tgc/Cgc 0 +TP53 UCSF GRCh37 17 7579310 7579310 + splice_donor_variant Splice_Site SNP A A C NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 17 19 55 0 ENST00000269305.4:c.375+2T>G p.X125_splice ENST00000269305 NM_001126112.2 0 +TP53I13 UCSF GRCh37 17 27898710 27898710 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 65 8 29 0 ENST00000301057.7:c.285C>T p.Thr95= p.T95= ENST00000301057 NM_138349.2 95 acC/acT 0 +TPCN2 UCSF GRCh37 11 68840147 68840147 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 4 13 0 ENST00000294309.3:c.1114G>A p.Asp372Asn p.D372N ENST00000294309 NM_139075.3 372 Gac/Aac 0 +TPPP2 UCSF GRCh37 14 21498789 21498789 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 10 6 13 0 ENST00000321760.6:c.49G>A p.Glu17Lys p.E17K ENST00000321760 NM_173846.4 17 Gaa/Aaa 0 +TPR UCSF GRCh37 1 186310473 186310473 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 51 46 79 0 ENST00000367478.4:c.3799G>A p.Glu1267Lys p.E1267K ENST00000367478 NM_003292.2 1267 Gaa/Aaa 0 +TPRG1L UCSF GRCh37 1 3542308 3542308 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 18 22 0 ENST00000378344.2:c.325C>T p.Leu109= p.L109= ENST00000378344 NM_182752.3 109 Ctg/Ttg 0 +TPX2 UCSF GRCh37 20 30366771 30366771 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 14 77 0 ENST00000300403.6:c.1038C>T p.Ser346= p.S346= ENST00000300403 NM_012112.4 346 agC/agT 0 +TRAF1 UCSF GRCh37 9 123675816 123675816 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 6 15 0 ENST00000373887.3:c.495C>T p.Tyr165= p.Y165= ENST00000373887 NM_005658.4 165 taC/taT 0 +TRAF3 UCSF GRCh37 14 103355934 103355934 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 29 94 0 ENST00000560371.1:c.689G>A p.Ser230Asn p.S230N ENST00000560371 NM_145725.2 230 aGc/aAc 0 +TRAF3IP1 UCSF GRCh37 2 239234489 239234489 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 31 93 0 ENST00000373327.4:c.232G>A p.Asp78Asn p.D78N ENST00000373327 NM_015650.3 78 Gac/Aac 0 +TRAF3IP1 UCSF GRCh37 2 239234494 239234494 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 34 87 0 ENST00000373327.4:c.237G>A p.Val79= p.V79= ENST00000373327 NM_015650.3 79 gtG/gtA 0 +TRAF7 UCSF GRCh37 16 2223935 2223935 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 20 34 0 ENST00000326181.6:c.1149G>A p.Gln383= p.Q383= ENST00000326181 NM_032271.2 383 caG/caA 0 +TRANK1 UCSF GRCh37 3 36897308 36897308 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 28 132 0 ENST00000429976.2:c.3773G>A p.Ser1258Asn p.S1258N ENST00000429976 1258 aGt/aAt 0 +TRANK1 UCSF GRCh37 3 36902590 36902590 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 46 16 103 0 ENST00000429976.2:c.1170C>T p.Phe390= p.F390= ENST00000429976 390 ttC/ttT 0 +TRAPPC10 UCSF GRCh37 21 45522744 45522744 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 39 19 29 0 ENST00000291574.4:c.3432G>A p.Arg1144= p.R1144= ENST00000291574 NM_003274.4 1144 agG/agA 0 +TRIB3 UCSF GRCh37 20 368870 368870 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 4 15 0 ENST00000217233.3:c.216C>T p.Val72= p.V72= ENST00000217233 NM_021158.3 72 gtC/gtT 0 +TRIM10 UCSF GRCh37 6 30122090 30122090 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 8 18 0 ENST00000449742.2:c.1102G>A p.Val368Met p.V368M ENST00000449742 NM_006778.3 368 Gtg/Atg 0 +TRIM33 UCSF GRCh37 1 114967346 114967346 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 35 24 59 0 ENST00000358465.2:c.1727A>G p.Gln576Arg p.Q576R ENST00000358465 NM_015906.3 576 cAa/cGa 0 +TRIM45 UCSF GRCh37 1 117663497 117663497 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 33 7 35 0 ENST00000256649.4:c.327G>A p.Lys109= p.K109= ENST00000256649 NM_025188.3 109 aaG/aaA 0 +TRIO UCSF GRCh37 5 14369561 14369561 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 20 22 0 ENST00000344204.4:c.3145C>T p.Pro1049Ser p.P1049S ENST00000344204 NM_007118.2 1049 Cca/Tca 0 +TRIO UCSF GRCh37 5 14368959 14368959 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 13 59 0 ENST00000344204.4:c.3017G>A p.Arg1006His p.R1006H ENST00000344204 NM_007118.2 1006 cGc/cAc 0 +TRIO UCSF GRCh37 5 14359496 14359496 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 27 19 40 0 ENST00000344204.4:c.2247C>T p.Pro749= p.P749= ENST00000344204 NM_007118.2 749 ccC/ccT 0 +TRMT1L UCSF GRCh37 1 185108515 185108515 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 31 8 36 0 ENST00000367506.5:c.1306G>A p.Val436Ile p.V436I ENST00000367506 NM_001202423.1 436 Gta/Ata 0 +TRPC4AP UCSF GRCh37 20 33637770 33637770 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 70 19 77 0 ENST00000252015.2:c.556G>A p.Glu186Lys p.E186K ENST00000252015 186 Gaa/Aaa 0 +TRPM2 UCSF GRCh37 21 45798961 45798961 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 7 22 0 ENST00000397928.1:c.1096G>A p.Val366Met p.V366M ENST00000397928 NM_003307.3 366 Gtg/Atg 0 +TRPM7 UCSF GRCh37 15 50935715 50935715 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 40 94 0 ENST00000313478.7:c.357C>T p.Val119= p.V119= ENST00000313478 NM_017672.4 119 gtC/gtT 0 +TRPS1 UCSF GRCh37 8 116430604 116430604 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 112 17 94 0 ENST00000395715.3:c.2777G>A p.Gly926Asp p.G926D ENST00000395715 NM_014112.2 926 gGc/gAc 0 +TRPV3 UCSF GRCh37 17 3427628 3427628 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 55 30 42 0 ENST00000301365.4:c.1607C>T p.Ser536Phe p.S536F ENST00000301365 536 tCt/tTt 0 +TRRAP UCSF GRCh37 7 98529278 98529278 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 44 8 51 0 ENST00000359863.4:c.3842C>T p.Pro1281Leu p.P1281L ENST00000359863 NM_001244580.1 1281 cCc/cTc 0 +TRRAP UCSF GRCh37 7 98567904 98567904 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 15 13 0 ENST00000359863.4:c.7661C>T p.Ser2554Phe p.S2554F ENST00000359863 NM_001244580.1 2554 tCc/tTc 0 +TSHR UCSF GRCh37 14 81610572 81610572 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 62 53 116 0 ENST00000298171.2:c.2170G>A p.Val724Ile p.V724I ENST00000298171 NM_000369.2 724 Gtt/Att 0 +TSHZ2 UCSF GRCh37 20 51870400 51870400 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 34 49 0 ENST00000371497.5:c.403G>A p.Asp135Asn p.D135N ENST00000371497 NM_173485.5 135 Gat/Aat 0 +TSPAN10 UCSF GRCh37 17 79612115 79612115 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 32 6 25 0 ENST00000328585.4:c.134G>A p.Cys45Tyr p.C45Y ENST00000328585 NM_031945.3 45 tGc/tAc 0 +TSPY8 UCSF GRCh37 Y 9196995 9196995 + intron_variant Intron SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 12 77 0 ENST00000330628.9:c.237+1307G>A *79* ENST00000330628 0 +TSSK1B UCSF GRCh37 5 112769861 112769861 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 43 8 41 0 ENST00000390666.3:c.676C>T p.Arg226Cys p.R226C ENST00000390666 NM_032028.3 226 Cgt/Tgt 0 +TSTA3 UCSF GRCh37 8 144698315 144698315 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 19 29 54 0 ENST00000425753.2:c.222G>A p.Gly74= p.G74= ENST00000425753 NM_003313.3 74 ggG/ggA 0 +TTC25 UCSF GRCh37 17 40117175 40117175 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 49 13 31 0 ENST00000591658.1:n.1564G>A *522* ENST00000591658 0 +TTC28 UCSF GRCh37 22 28559236 28559236 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 38 61 0 ENST00000397906.2:c.1285G>A p.Glu429Lys p.E429K ENST00000397906 NM_001145418.1 429 Gag/Aag 0 +TTLL4 UCSF GRCh37 2 219610436 219610436 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 5 9 0 ENST00000392102.1:c.1809G>A p.Gln603= p.Q603= ENST00000392102 NM_014640.4 603 caG/caA 0 +TTLL9 UCSF GRCh37 20 30526972 30526972 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 11 24 0 ENST00000375938.4:c.1146G>A p.Gly382= p.G382= ENST00000375938 382 ggG/ggA 0 +TTN UCSF GRCh37 2 179394972 179394972 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 143 23 146 0 ENST00000589042.1:c.106370G>A p.Gly35457Glu p.G35457E ENST00000589042 NM_001267550.1 35457 gGa/gAa 0 +TTN UCSF GRCh37 2 179456088 179456088 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 195 33 171 0 ENST00000589042.1:c.60364G>A p.Asp20122Asn p.D20122N ENST00000589042 NM_001267550.1 20122 Gat/Aat 0 +TTN UCSF GRCh37 2 179483047 179483047 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 125 84 182 0 ENST00000589042.1:c.47138G>A p.Ser15713Asn p.S15713N ENST00000589042 NM_001267550.1 15713 aGt/aAt 0 +TTN UCSF GRCh37 2 179426824 179426824 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 180 21 158 0 ENST00000589042.1:c.84035C>T p.Ser28012Phe p.S28012F ENST00000589042 NM_001267550.1 28012 tCt/tTt 0 +TTN UCSF GRCh37 2 179500785 179500785 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 78 53 108 0 ENST00000589042.1:c.41513C>T p.Thr13838Ile p.T13838I ENST00000589042 NM_001267550.1 13838 aCc/aTc 0 +TTN UCSF GRCh37 2 179411986 179411986 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 131 31 122 0 ENST00000589042.1:c.94266C>T p.Ala31422= p.A31422= ENST00000589042 NM_001267550.1 31422 gcC/gcT 0 +TUB UCSF GRCh37 11 8123085 8123085 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 31 0 ENST00000305253.4:c.1605G>A p.Met535Ile p.M535I ENST00000305253 NM_003320.4 535 atG/atA 0 +TUBAL3 UCSF GRCh37 10 5436047 5436047 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 48 40 47 0 ENST00000380419.3:c.774C>T p.Asp258= p.D258= ENST00000380419 NM_024803.2 258 gaC/gaT 0 +TUBGCP2 UCSF GRCh37 10 135102493 135102493 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 13 26 44 0 ENST00000543663.1:c.1476C>T p.Gly492= p.G492= ENST00000543663 492 ggC/ggT 0 +TUBGCP3 UCSF GRCh37 13 113201934 113201934 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 13 50 0 ENST00000261965.3:c.1168G>A p.Gly390Arg p.G390R ENST00000261965 NM_006322.4 390 Gga/Aga 0 +TULP1 UCSF GRCh37 6 35480615 35480615 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 33 4 16 0 ENST00000229771.6:c.21C>T p.Thr7= p.T7= ENST00000229771 NM_003322.3 7 acC/acT 0 +TYW1B UCSF GRCh37 7 72277868 72277868 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 27 50 0 ENST00000438904.2:c.514G>A p.Val172Ile p.V172I ENST00000438904 172 Gtt/Att 0 +UBA6 UCSF GRCh37 4 68492153 68492153 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 13 96 0 ENST00000322244.5:c.2443C>T p.Pro815Ser p.P815S ENST00000322244 NM_018227.5 815 Cct/Tct 0 +UBA6 UCSF GRCh37 4 68547836 68547836 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 9 54 0 ENST00000322244.5:c.229+1G>A p.X77_splice ENST00000322244 NM_018227.5 0 +UBASH3B UCSF GRCh37 11 122680560 122680560 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 41 35 62 0 ENST00000284273.5:c.1916G>A p.Gly639Asp p.G639D ENST00000284273 NM_032873.4 639 gGc/gAc 0 +UBE2Q2 UCSF GRCh37 15 76183356 76183356 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 14 104 0 ENST00000267938.4:c.1029+1G>A p.X343_splice ENST00000267938 NM_173469.2 0 +UBFD1 UCSF GRCh37 16 23569458 23569458 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 7 14 0 ENST00000395878.3:c.213C>T p.Val71= p.V71= ENST00000395878 NM_019116.2 71 gtC/gtT 0 +UBOX5 UCSF GRCh37 20 3102359 3102359 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 8 16 0 ENST00000217173.2:c.926G>A p.Gly309Glu p.G309E ENST00000217173 NM_001267584.1 309 gGg/gAg 0 +UBR2 UCSF GRCh37 6 42626058 42626058 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 28 102 0 ENST00000372899.1:c.3063G>A p.Glu1021= p.E1021= ENST00000372899 NM_015255.2 1021 gaG/gaA 0 +UBR4 UCSF GRCh37 1 19453006 19453006 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 17 77 0 ENST00000375254.3:c.9372G>A p.Leu3124= p.L3124= ENST00000375254 NM_020765.2 3124 ttG/ttA 0 +UBR4 UCSF GRCh37 1 19411132 19411132 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 19 29 0 ENST00000375254.3:c.14874C>T p.Ile4958= p.I4958= ENST00000375254 NM_020765.2 4958 atC/atT 0 +UCK1 UCSF GRCh37 9 134400576 134400576 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 41 14 26 0 ENST00000372211.3:c.700G>A p.Asp234Asn p.D234N ENST00000372211 234 Gac/Aac 0 +UCMA UCSF GRCh37 10 13264130 13264130 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 11 7 21 0 ENST00000378681.3:c.390C>T p.Ser130= p.S130= ENST00000378681 NM_145314.1 130 tcC/tcT 0 +UFD1L UCSF GRCh37 22 19455456 19455456 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 40 81 0 ENST00000263202.10:c.362C>T p.Thr121Ile p.T121I ENST00000263202 NM_005659.6 121 aCc/aTc 0 +UGGT1 UCSF GRCh37 2 128931358 128931358 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 22 51 0 ENST00000259253.6:c.3298G>A p.Asp1100Asn p.D1100N ENST00000259253 NM_020120.3 1100 Gac/Aac 0 +UGT2B4 UCSF GRCh37 4 70352375 70352375 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 119 28 157 0 ENST00000305107.6:c.1042G>A p.Gly348Arg p.G348R ENST00000305107 NM_021139.2 348 Gga/Aga 0 +ULK2 UCSF GRCh37 17 19687113 19687113 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 38 5 49 0 ENST00000395544.4:c.2357C>T p.Ala786Val p.A786V ENST00000395544 NM_014683.3 786 gCa/gTa 0 +UNC13B UCSF GRCh37 9 35399159 35399159 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 15 44 0 ENST00000378495.3:c.3829C>T p.Leu1277Phe p.L1277F ENST00000378495 NM_006377.3 1277 Ctc/Ttc 0 +UNC13C UCSF GRCh37 15 54860025 54860025 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 104 18 139 0 ENST00000260323.11:c.5986C>T p.Leu1996= p.L1996= ENST00000260323 NM_001080534.1 1996 Ctg/Ttg 0 +UNC45A UCSF GRCh37 15 91491966 91491966 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 9 0 ENST00000418476.2:c.1820C>T p.Pro607Leu p.P607L ENST00000418476 NM_018671.3 607 cCc/cTc 0 +UNC45A UCSF GRCh37 15 91488139 91488139 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 28 67 0 ENST00000418476.2:c.1045G>A p.Glu349Lys p.E349K ENST00000418476 NM_018671.3 349 Gaa/Aaa 0 +UNC80 UCSF GRCh37 2 210704070 210704070 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 53 15 52 0 ENST00000439458.1:c.3166G>A p.Ala1056Thr p.A1056T ENST00000439458 NM_032504.1 1056 Gcc/Acc 0 +UNC80 UCSF GRCh37 2 210834555 210834555 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 11 44 0 ENST00000439458.1:c.7872G>A p.Arg2624= p.R2624= ENST00000439458 NM_032504.1 2624 agG/agA 0 +UNC93A UCSF GRCh37 6 167711551 167711551 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 7 29 0 ENST00000230256.3:c.618C>T p.Ile206= p.I206= ENST00000230256 NM_018974.3 206 atC/atT 0 +UNC93B1 UCSF GRCh37 11 67765232 67765232 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 3 15 0 ENST00000227471.2:c.819G>A p.Lys273= p.K273= ENST00000227471 NM_030930.2 273 aaG/aaA 0 +UNK UCSF GRCh37 17 73816087 73816087 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 26 29 0 ENST00000589666.1:c.1735C>T p.Pro579Ser p.P579S ENST00000589666 NM_001080419.2 579 Cct/Tct 0 +UNKL UCSF GRCh37 16 1442949 1442949 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 6 10 12 0 ENST00000389221.4:c.957C>T p.Gly319= p.G319= ENST00000389221 NM_001193388.3 319 ggC/ggT 0 +UPK1B UCSF GRCh37 3 118913220 118913220 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 17 35 78 0 ENST00000264234.3:c.623G>A p.Gly208Asp p.G208D ENST00000264234 NM_006952.3 208 gGc/gAc 0 +URB1 UCSF GRCh37 21 33756656 33756656 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 85 47 108 0 ENST00000382751.3:c.400C>T p.Leu134Phe p.L134F ENST00000382751 NM_014825.2 134 Ctc/Ttc 0 +USH1C UCSF GRCh37 11 17517140 17517140 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 39 10 37 0 ENST00000005226.7:c.2631G>A p.Gly877= p.G877= ENST00000005226 NM_153676.3 877 ggG/ggA 0 +USH2A UCSF GRCh37 1 216011434 216011434 + synonymous_variant Silent SNP G G A NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 49 43 90 0 ENST00000307340.3:c.9270C>T p.Cys3090= p.C3090= ENST00000307340 NM_206933.2 3090 tgC/tgT 0 +USH2A UCSF GRCh37 1 215848193 215848193 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 19 32 0 ENST00000307340.3:c.13060G>A p.Ala4354Thr p.A4354T ENST00000307340 NM_206933.2 4354 Gct/Act 0 +USH2A UCSF GRCh37 1 216262370 216262370 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 37 131 0 ENST00000307340.3:c.4870G>A p.Asp1624Asn p.D1624N ENST00000307340 NM_206933.2 1624 Gat/Aat 0 +USHBP1 UCSF GRCh37 19 17362429 17362429 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 37 16 33 0 ENST00000252597.3:c.1884G>A p.Gln628= p.Q628= ENST00000252597 NM_031941.3 628 caG/caA 0 +USP16 UCSF GRCh37 21 30411418 30411418 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 67 32 48 0 ENST00000334352.4:c.804G>A p.Met268Ile p.M268I ENST00000334352 NM_001032410.1 268 atG/atA 0 +USP17L2 UCSF GRCh37 8 11995414 11995414 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 184 27 175 0 ENST00000333796.3:c.856G>A p.Val286Ile p.V286I ENST00000333796 NM_201402.2 286 Gtc/Atc 0 +USP24 UCSF GRCh37 1 55604643 55604643 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 9 74 0 ENST00000294383.6:c.2791G>A p.Ala931Thr p.A931T ENST00000294383 NM_015306.2 931 Gca/Aca 0 +USP31 UCSF GRCh37 16 23080422 23080422 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 60 12 62 0 ENST00000219689.7:c.3004C>T p.Pro1002Ser p.P1002S ENST00000219689 NM_020718.3 1002 Cca/Tca 0 +USP33 UCSF GRCh37 1 78194332 78194332 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 44 69 0 ENST00000370793.1:c.876G>A p.Met292Ile p.M292I ENST00000370793 NM_015017.4 292 atG/atA 0 +USP33 UCSF GRCh37 1 78167082 78167082 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 96 45 86 0 ENST00000370793.1:c.2574G>A p.Trp858Ter p.W858* ENST00000370793 NM_015017.4 858 tgG/tgA 0 +USP34 UCSF GRCh37 2 61441210 61441210 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 21 51 0 ENST00000398571.2:c.8667C>T p.Ala2889= p.A2889= ENST00000398571 NM_014709.3 2889 gcC/gcT 0 +USP34 UCSF GRCh37 2 61447539 61447539 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 90 60 106 0 ENST00000398571.2:c.7953C>T p.Pro2651= p.P2651= ENST00000398571 NM_014709.3 2651 ccC/ccT 0 +USP37 UCSF GRCh37 2 219360568 219360568 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 73 17 107 0 ENST00000258399.3:c.1387C>T p.Pro463Ser p.P463S ENST00000258399 NM_020935.2 463 Cca/Tca 0 +USP37 UCSF GRCh37 2 219353081 219353081 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 50 106 0 ENST00000258399.3:c.1536G>A p.Arg512= p.R512= ENST00000258399 NM_020935.2 512 agG/agA 0 +USP40 UCSF GRCh37 2 234429752 234429752 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 58 51 87 0 ENST00000450966.1:c.2243C>T p.Thr748Ile p.T748I ENST00000450966 NM_018218.2 748 aCc/aTc 0 +USP42 UCSF GRCh37 7 6155129 6155129 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 116 18 97 0 ENST00000306177.5:c.417G>A p.Met139Ile p.M139I ENST00000306177 NM_032172.2 139 atG/atA 0 +USP7 UCSF GRCh37 16 9002227 9002227 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 14 67 0 ENST00000344836.4:c.1242G>A p.Gln414= p.Q414= ENST00000344836 NM_003470.2 414 caG/caA 0 +VAC14 UCSF GRCh37 16 70806067 70806067 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 3 32 0 ENST00000261776.5:c.1105G>A p.Asp369Asn p.D369N ENST00000261776 NM_018052.3 369 Gat/Aat 0 +VAV2 UCSF GRCh37 9 136637120 136637120 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 23 44 0 ENST00000371850.3:c.2184G>A p.Trp728Ter p.W728* ENST00000371850 NM_001134398.1 728 tgG/tgA 0 +VCAN UCSF GRCh37 5 82837070 82837070 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 54 24 76 0 ENST00000265077.3:c.8248G>A p.Glu2750Lys p.E2750K ENST00000265077 NM_004385.4 2750 Gag/Aag 0 +VCAN UCSF GRCh37 5 82815919 82815919 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 57 107 0 ENST00000265077.3:c.1794G>A p.Glu598= p.E598= ENST00000265077 NM_004385.4 598 gaG/gaA 0 +VIL1 UCSF GRCh37 2 219294323 219294323 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 7 22 0 ENST00000248444.5:c.774G>A p.Val258= p.V258= ENST00000248444 NM_007127.2 258 gtG/gtA 0 +VPRBP UCSF GRCh37 3 51466911 51466911 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 14 38 124 0 ENST00000423656.1:c.192G>A p.Leu64= p.L64= ENST00000423656 64 ttG/ttA 0 +VPS13D UCSF GRCh37 1 12336545 12336545 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 77 17 61 0 ENST00000358136.3:c.2900G>A p.Gly967Asp p.G967D ENST00000358136 NM_015378.2 967 gGt/gAt 0 +VPS36 UCSF GRCh37 13 53000202 53000202 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 53 26 73 0 ENST00000378060.4:c.640-1G>A p.X214_splice ENST00000378060 NM_016075.2 0 +VPS52 UCSF GRCh37 6 33234964 33234964 + splice_donor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 17 27 0 ENST00000445902.2:c.1125+1G>A p.X375_splice ENST00000445902 NM_022553.4 0 +VPS53 UCSF GRCh37 17 556631 556631 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 89 21 94 0 ENST00000437048.2:c.508C>T p.Gln170Ter p.Q170* ENST00000437048 NM_001128159.2 170 Caa/Taa 0 +VSTM2A UCSF GRCh37 7 54617556 54617556 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 82 13 90 0 ENST00000407838.3:c.327C>T p.Ser109= p.S109= ENST00000407838 NM_182546.2 109 tcC/tcT 0 +VSX2 UCSF GRCh37 14 74726340 74726340 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 29 8 29 0 ENST00000261980.2:c.615G>A p.Lys205= p.K205= ENST00000261980 NM_182894.2 205 aaG/aaA 0 +VTCN1 UCSF GRCh37 1 117690383 117690383 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 62 25 83 0 ENST00000369458.3:c.746G>A p.Ser249Asn p.S249N ENST00000369458 NM_024626.3 249 aGt/aAt 0 +VWA3A UCSF GRCh37 16 22137503 22137503 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 123 63 99 0 ENST00000389398.5:c.1537G>A p.Val513Ile p.V513I ENST00000389398 NM_173615.3 513 Gtt/Att 0 +WARS2 UCSF GRCh37 1 119584944 119584944 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 57 10 39 0 ENST00000235521.4:c.458G>A p.Gly153Asp p.G153D ENST00000235521 NM_201263.2 153 gGc/gAc 0 +WDFY3 UCSF GRCh37 4 85707170 85707170 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 41 123 0 ENST00000295888.4:c.4024G>A p.Val1342Met p.V1342M ENST00000295888 NM_014991.4 1342 Gtg/Atg 0 +WDFY4 UCSF GRCh37 10 49951403 49951403 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 11 10 0 ENST00000325239.5:c.2269C>T p.Pro757Ser p.P757S ENST00000325239 NM_020945.1 757 Cca/Tca 0 +WDR1 UCSF GRCh37 4 10100664 10100664 + stop_gained Nonsense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 15 24 0 ENST00000499869.2:c.329G>A p.Trp110Ter p.W110* ENST00000499869 110 tGg/tAg 0 +WDR19 UCSF GRCh37 4 39207193 39207193 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 122 20 103 0 ENST00000399820.3:c.727G>A p.Gly243Ser p.G243S ENST00000399820 NM_025132.3 243 Ggc/Agc 0 +WDR19 UCSF GRCh37 4 39236403 39236403 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 106 16 98 0 ENST00000399820.3:c.2271G>A p.Gln757= p.Q757= ENST00000399820 NM_025132.3 757 caG/caA 0 +WDR3 UCSF GRCh37 1 118492674 118492674 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 79 64 129 0 ENST00000349139.5:c.1667G>A p.Ser556Asn p.S556N ENST00000349139 NM_006784.2 556 aGt/aAt 0 +WDR5 UCSF GRCh37 9 137005076 137005076 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 7 30 0 ENST00000358625.3:c.77G>A p.Ser26Asn p.S26N ENST00000358625 NM_017588.2 26 aGc/aAc 0 +WDR62 UCSF GRCh37 19 36564358 36564358 + stop_gained Nonsense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 22 24 13 0 ENST00000401500.2:c.1158G>A p.Trp386Ter p.W386* ENST00000401500 NM_001083961.1 386 tgG/tgA 0 +WDR81 UCSF GRCh37 17 1635993 1635993 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 4 9 0 ENST00000409644.1:c.4357G>A p.Gly1453Ser p.G1453S ENST00000409644 NM_001163809.1 1453 Ggc/Agc 0 +WDR87 UCSF GRCh37 19 38377201 38377201 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 105 71 130 0 ENST00000303868.5:c.6993C>T p.Cys2331= p.C2331= ENST00000303868 NM_031951.3 2331 tgC/tgT 0 +WDR93 UCSF GRCh37 15 90258214 90258214 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 66 14 79 0 ENST00000268130.7:c.644C>T p.Ala215Val p.A215V ENST00000268130 NM_020212.1 215 gCc/gTc 0 +WDR93 UCSF GRCh37 15 90270407 90270407 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 35 24 61 0 ENST00000268130.7:c.900C>T p.Pro300= p.P300= ENST00000268130 NM_020212.1 300 ccC/ccT 0 +WFDC3 UCSF GRCh37 20 44417682 44417682 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 37 76 0 ENST00000243938.4:c.99C>T p.Cys33= p.C33= ENST00000243938 NM_080614.1 33 tgC/tgT 0 +WHSC1 UCSF GRCh37 4 1902406 1902406 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 48 77 0 ENST00000382891.5:c.25C>T p.Pro9Ser p.P9S ENST00000382891 NM_133335.3 9 Ccc/Tcc 0 +WIPF1 UCSF GRCh37 2 175432672 175432672 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 25 7 22 0 ENST00000392547.2:c.1259C>T p.Pro420Leu p.P420L ENST00000392547 NM_003387.4 420 cCt/cTt 0 +WIPF3 UCSF GRCh37 7 29874426 29874426 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 26 23 49 0 ENST00000409290.1:c.86C>T p.Pro29Leu p.P29L ENST00000409290 NM_001080529.2 29 cCc/cTc 0 +WLS UCSF GRCh37 1 68619204 68619204 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 54 16 43 0 ENST00000354777.2:c.793G>A p.Glu265Lys p.E265K ENST00000354777 NM_001002292.3 265 Gaa/Aaa 0 +WNK3 UCSF GRCh37 X 54319365 54319365 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 4 35 0 ENST00000354646.2:c.1993C>T p.Pro665Ser p.P665S ENST00000354646 NM_020922.4 665 Ccc/Tcc 0 +WNK4 UCSF GRCh37 17 40948172 40948172 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 42 14 45 0 ENST00000246914.5:c.3463C>T p.Leu1155= p.L1155= ENST00000246914 NM_032387.4 1155 Cta/Tta 0 +WNT2B UCSF GRCh37 1 113010181 113010181 + missense_variant Missense_Mutation SNP G G T NOVEL P01_Rec Untested WXS Illumina HiSeq 17 4 27 1 ENST00000369686.5:c.22G>T p.Val8Leu p.V8L ENST00000369686 NM_004185.3 8 Gta/Tta 0 +WNT4 UCSF GRCh37 1 22447772 22447772 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 22 11 23 0 ENST00000290167.6:c.520G>A p.Glu174Lys p.E174K ENST00000290167 NM_030761.4 174 Gag/Aag 0 +WNT5A UCSF GRCh37 3 55513516 55513516 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 219 34 152 0 ENST00000474267.1:c.217G>A p.Ala73Thr p.A73T ENST00000474267 73 Gca/Aca 0 +WWC1 UCSF GRCh37 5 167798429 167798429 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 21 3 17 0 ENST00000521089.1:c.120G>A p.Arg40= p.R40= ENST00000521089 40 agG/agA 0 +WWC2 UCSF GRCh37 4 184205543 184205543 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 12 17 38 0 ENST00000403733.3:c.3048G>A p.Arg1016= p.R1016= ENST00000403733 NM_024949.5 1016 agG/agA 0 +XAB2 UCSF GRCh37 19 7689302 7689302 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 24 5 16 0 ENST00000358368.4:c.852G>A p.Arg284= p.R284= ENST00000358368 NM_020196.2 284 cgG/cgA 0 +XIRP1 UCSF GRCh37 3 39229241 39229241 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 7 42 0 ENST00000340369.3:c.1696G>A p.Glu566Lys p.E566K ENST00000340369 NM_194293.2 566 Gag/Aag 0 +XPO6 UCSF GRCh37 16 28192328 28192328 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 25 61 0 ENST00000304658.5:c.28G>A p.Ala10Thr p.A10T ENST00000304658 NM_015171.3 10 Gca/Aca 0 +XPOT UCSF GRCh37 12 64813888 64813888 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 70 12 73 0 ENST00000332707.5:c.528G>A p.Arg176= p.R176= ENST00000332707 NM_007235.4 176 agG/agA 0 +XRCC2 UCSF GRCh37 7 152346419 152346419 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 65 11 82 0 ENST00000359321.1:c.151G>A p.Gly51Arg p.G51R ENST00000359321 NM_005431.1 51 Gga/Aga 0 +XRCC4 UCSF GRCh37 5 82500646 82500646 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 48 6 37 0 ENST00000511817.1:c.651C>T p.Ile217= p.I217= ENST00000511817 217 atC/atT 0 +YIPF1 UCSF GRCh37 1 54348887 54348887 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 38 32 76 0 ENST00000072644.1:c.94G>A p.Asp32Asn p.D32N ENST00000072644 NM_018982.4 32 Gat/Aat 0 +YME1L1 UCSF GRCh37 10 27406657 27406657 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 83 25 101 0 ENST00000326799.3:c.1739-1G>A p.X580_splice ENST00000326799 NM_139312.2 0 +YTHDC2 UCSF GRCh37 5 112871458 112871458 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 23 25 75 0 ENST00000161863.4:c.1065C>T p.Leu355= p.L355= ENST00000161863 NM_022828.3 355 ctC/ctT 0 +YTHDF2 UCSF GRCh37 1 29069935 29069935 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 60 19 82 0 ENST00000373812.3:c.1153C>T p.Pro385Ser p.P385S ENST00000373812 NM_016258.2 385 Ccc/Tcc 0 +ZAN UCSF GRCh37 7 100350516 100350516 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 16 9 33 0 ENST00000546292.1:c.2788C>T p.Pro930Ser p.P930S ENST00000546292 NM_173059.1 930 Ccc/Tcc 0 +ZBTB1 UCSF GRCh37 14 64989761 64989761 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 130 63 162 0 ENST00000394712.2:c.1539C>T p.Asp513= p.D513= ENST00000394712 NM_001123329.1 513 gaC/gaT 0 +ZBTB10 UCSF GRCh37 8 81412055 81412055 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 174 35 180 0 ENST00000430430.1:c.1299C>T p.Ser433= p.S433= ENST00000430430 433 agC/agT 0 +ZC3H12A UCSF GRCh37 1 37945949 37945949 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 9 15 16 0 ENST00000373087.6:c.502C>T p.Leu168= p.L168= ENST00000373087 NM_025079.2 168 Ctg/Ttg 0 +ZC3H4 UCSF GRCh37 19 47588394 47588394 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 27 4 49 0 ENST00000253048.5:c.1026C>T p.Gly342= p.G342= ENST00000253048 NM_015168.1 342 ggC/ggT 0 +ZCCHC12 UCSF GRCh37 X 117959756 117959756 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 37 52 0 ENST00000310164.2:c.549G>A p.Glu183= p.E183= ENST00000310164 NM_173798.2 183 gaG/gaA 0 +ZCCHC6 UCSF GRCh37 9 88903610 88903610 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 20 6 32 0 ENST00000375963.3:c.4470G>A p.Arg1490= p.R1490= ENST00000375963 NM_001185059.1 1490 agG/agA 0 +ZDBF2 UCSF GRCh37 2 207175568 207175568 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 82 66 134 0 ENST00000374423.3:c.6316C>T p.Pro2106Ser p.P2106S ENST00000374423 NM_020923.1 2106 Cct/Tct 0 +ZFHX2 UCSF GRCh37 14 24003498 24003498 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 5 31 0 ENST00000419474.3:c.1037C>T p.Pro346Leu p.P346L ENST00000419474 NM_033400.2 346 cCc/cTc 0 +ZFHX2 UCSF GRCh37 14 24002867 24002867 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 65 25 61 0 ENST00000419474.3:c.1668C>T p.Pro556= p.P556= ENST00000419474 NM_033400.2 556 ccC/ccT 0 +ZFHX4 UCSF GRCh37 8 77764123 77764123 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 130 27 153 0 ENST00000521891.2:c.4966G>A p.Ala1656Thr p.A1656T ENST00000521891 NM_024721.4 1656 Gca/Aca 0 +ZFYVE16 UCSF GRCh37 5 79734594 79734594 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 78 18 78 0 ENST00000338008.5:c.2090C>T p.Pro697Leu p.P697L ENST00000338008 NM_014733.3 697 cCa/cTa 0 +ZFYVE16 UCSF GRCh37 5 79752881 79752881 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 71 12 82 0 ENST00000338008.5:c.3913G>A p.Ala1305Thr p.A1305T ENST00000338008 NM_014733.3 1305 Gcc/Acc 0 +ZFYVE28 UCSF GRCh37 4 2306889 2306889 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 21 8 18 0 ENST00000290974.2:c.1178G>A p.Gly393Asp p.G393D ENST00000290974 NM_020972.2 393 gGc/gAc 0 +ZFYVE28 UCSF GRCh37 4 2306375 2306375 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0012 P01_Rec Untested WXS Illumina HiSeq 5 12 8 0 ENST00000290974.2:c.1692C>T p.Cys564= p.C564= ENST00000290974 NM_020972.2 564 tgC/tgT 0 +ZIM3 UCSF GRCh37 19 57647316 57647316 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 52 20 123 0 ENST00000269834.1:c.389G>A p.Gly130Asp p.G130D ENST00000269834 NM_052882.1 130 gGc/gAc 0 +ZKSCAN3 UCSF GRCh37 6 28333633 28333633 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 96 39 60 0 ENST00000377255.3:c.1188G>A p.Lys396= p.K396= ENST00000377255 NM_001242894.1 396 aaG/aaA 0 +ZKSCAN5 UCSF GRCh37 7 99129352 99129352 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 83 43 67 0 ENST00000394170.2:c.2000G>A p.Gly667Glu p.G667E ENST00000394170 NM_014569.3 667 gGg/gAg 0 +ZMYM4 UCSF GRCh37 1 35873697 35873697 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 89 35 82 0 ENST00000314607.6:c.3885G>A p.Arg1295= p.R1295= ENST00000314607 NM_005095.2 1295 cgG/cgA 0 +ZNF17 UCSF GRCh37 19 57932525 57932525 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 47 17 118 0 ENST00000601808.1:c.1665G>A p.Glu555= p.E555= ENST00000601808 NM_006959.2 555 gaG/gaA 0 +ZNF211 UCSF GRCh37 19 58152405 58152405 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 12 24 41 0 ENST00000299871.5:c.746C>T p.Pro249Leu p.P249L ENST00000299871 NM_001265597.1 249 cCc/cTc 0 +ZNF224 UCSF GRCh37 19 44605305 44605305 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 50 46 78 0 ENST00000336976.6:c.162G>A p.Arg54= p.R54= ENST00000336976 NM_013398.2 54 agG/agA 0 +ZNF226 UCSF GRCh37 19 44681435 44681435 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 152 18 125 0 ENST00000590089.1:c.2020G>A p.Asp674Asn p.D674N ENST00000590089 674 Gat/Aat 0 +ZNF25 UCSF GRCh37 10 38241328 38241328 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 87 48 116 1 ENST00000302609.7:c.1098G>A p.Gly366= p.G366= ENST00000302609 NM_145011.2 366 ggG/ggA 0 +ZNF273 UCSF GRCh37 7 64377994 64377994 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 113 95 185 0 ENST00000476120.1:c.138C>T p.Phe46= p.F46= ENST00000476120 NM_021148.2 46 ttC/ttT 0 +ZNF275 UCSF GRCh37 X 152612560 152612560 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 20 12 17 0 ENST00000370251.3:c.417G>A p.Arg139= p.R139= ENST00000370251 NM_001080485.3 139 agG/agA 0 +ZNF28 UCSF GRCh37 19 53302984 53302984 + missense_variant Missense_Mutation SNP T T C NOVEL P01_Rec Untested WXS Illumina HiSeq 24 86 163 0 ENST00000457749.2:c.2114A>G p.Asn705Ser p.N705S ENST00000457749 NM_006969.3 705 aAc/aGc 0 +ZNF282 UCSF GRCh37 7 148910902 148910902 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 10 6 10 0 ENST00000262085.3:c.1176C>T p.Gly392= p.G392= ENST00000262085 NM_003575.2 392 ggC/ggT 0 +ZNF286B UCSF GRCh37 17 18565329 18565329 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 64 18 92 0 ENST00000545289.1:c.1490G>A p.Cys497Tyr p.C497Y ENST00000545289 NM_001145045.1 497 tGt/tAt 0 +ZNF292 UCSF GRCh37 6 87967271 87967271 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 25 44 124 0 ENST00000369577.3:c.3924C>T p.Ser1308= p.S1308= ENST00000369577 NM_015021.1 1308 tcC/tcT 0 +ZNF311 UCSF GRCh37 6 28966515 28966515 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 30 69 0 ENST00000377179.3:c.411C>T p.Tyr137= p.Y137= ENST00000377179 NM_001010877.2 137 taC/taT 0 +ZNF341 UCSF GRCh37 20 32354790 32354790 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 99 14 84 0 ENST00000342427.2:c.1335C>T p.Ser445= p.S445= ENST00000342427 NM_032819.3 445 agC/agT 0 +ZNF354A UCSF GRCh37 5 178152397 178152397 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 46 24 68 0 ENST00000335815.2:c.236G>A p.Gly79Asp p.G79D ENST00000335815 NM_005649.2 79 gGt/gAt 0 +ZNF354C UCSF GRCh37 5 178505788 178505788 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 61 47 91 0 ENST00000315475.6:c.355C>T p.His119Tyr p.H119Y ENST00000315475 NM_014594.1 119 Cac/Tac 0 +ZNF385B UCSF GRCh37 2 180634269 180634269 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 19 4 22 0 ENST00000410066.1:c.214C>T p.Pro72Ser p.P72S ENST00000410066 NM_152520.4 72 Cca/Tca 0 +ZNF410 UCSF GRCh37 14 74376048 74376048 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 61 49 109 0 ENST00000442160.3:c.969G>A p.Glu323= p.E323= ENST00000442160 NM_001242924.1 323 gaG/gaA 0 +ZNF425 UCSF GRCh37 7 148802315 148802315 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 29 23 38 0 ENST00000378061.2:c.648G>A p.Gln216= p.Q216= ENST00000378061 NM_001001661.2 216 caG/caA 0 +ZNF441 UCSF GRCh37 19 11891835 11891835 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 77 47 119 0 ENST00000357901.4:c.1196C>T p.Ala399Val p.A399V ENST00000357901 NM_152355.2 399 gCc/gTc 0 +ZNF451 UCSF GRCh37 6 57013222 57013222 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 37 12 57 0 ENST00000370706.4:c.2339G>A p.Ser780Asn p.S780N ENST00000370706 NM_001031623.2 780 aGt/aAt 0 +ZNF462 UCSF GRCh37 9 109687573 109687573 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 132 21 90 0 ENST00000277225.5:c.1380C>T p.Asn460= p.N460= ENST00000277225 460 aaC/aaT 0 +ZNF483 UCSF GRCh37 9 114304193 114304193 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 241 27 151 0 ENST00000309235.5:c.978G>A p.Arg326= p.R326= ENST00000309235 NM_133464.2 326 agG/agA 0 +ZNF493 UCSF GRCh37 19 21606767 21606767 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 57 122 0 ENST00000392288.2:c.1306G>A p.Glu436Lys p.E436K ENST00000392288 NM_001076678.2 436 Gaa/Aaa 0 +ZNF506 UCSF GRCh37 19 19916846 19916846 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 114 13 129 0 ENST00000443905.2:c.220C>T p.Pro74Ser p.P74S ENST00000443905 74 Ccc/Tcc 0 +ZNF507 UCSF GRCh37 19 32845510 32845510 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 34 22 81 0 ENST00000311921.4:c.1774G>A p.Glu592Lys p.E592K ENST00000311921 NM_014910.4 592 Gaa/Aaa 0 +ZNF518B UCSF GRCh37 4 10446731 10446731 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 129 91 188 0 ENST00000326756.3:c.1222G>A p.Val408Ile p.V408I ENST00000326756 NM_053042.2 408 Gtt/Att 0 +ZNF518B UCSF GRCh37 4 10445799 10445799 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 131 28 84 0 ENST00000326756.3:c.2154C>T p.Gly718= p.G718= ENST00000326756 NM_053042.2 718 ggC/ggT 0 +ZNF546 UCSF GRCh37 19 40520361 40520361 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 69 14 83 0 ENST00000347077.4:c.1184G>A p.Ser395Asn p.S395N ENST00000347077 NM_178544.3 395 aGt/aAt 0 +ZNF549 UCSF GRCh37 19 58049092 58049092 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 15 61 136 0 ENST00000376233.3:c.720C>T p.Val240= p.V240= ENST00000376233 NM_001199295.1 240 gtC/gtT 0 +ZNF555 UCSF GRCh37 19 2850645 2850645 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 80 57 97 0 ENST00000334241.4:c.64G>A p.Asp22Asn p.D22N ENST00000334241 NM_152791.4 22 Gat/Aat 0 +ZNF570 UCSF GRCh37 19 37975761 37975761 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 127 20 117 0 ENST00000330173.1:c.1237C>T p.Pro413Ser p.P413S ENST00000330173 NM_144694.1 413 Cct/Tct 0 +ZNF574 UCSF GRCh37 19 42582801 42582801 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 81 16 63 0 ENST00000600245.1:c.43C>T p.Arg15Cys p.R15C ENST00000600245 15 Cgc/Tgc 0 +ZNF598 UCSF GRCh37 16 2048796 2048796 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.086,1000g2011may_all_0.1651,snp132_rs1058474 P01_Rec Untested WXS Illumina HiSeq 9 5 8 0 ENST00000431526.1:c.2268G>A p.Arg756= p.R756= ENST00000431526 756 agG/agA 0 +ZNF609 UCSF GRCh37 15 64972457 64972457 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 31 13 29 0 ENST00000326648.3:c.3843G>A p.Lys1281= p.K1281= ENST00000326648 NM_015042.1 1281 aaG/aaA 0 +ZNF616 UCSF GRCh37 19 52620039 52620039 + missense_variant Missense_Mutation SNP A A C NOVEL P01_Rec somatic WXS Sanger Illumina HiSeq 11 87 150 0 ENST00000600228.1:c.378T>G p.His126Gln p.H126Q ENST00000600228 NM_178523.3 126 caT/caG 0 +ZNF638 UCSF GRCh37 2 71654398 71654398 + missense_variant Missense_Mutation SNP A A G NOVEL P01_Rec Untested WXS Illumina HiSeq 68 80 138 0 ENST00000409544.1:c.5399A>G p.Asp1800Gly p.D1800G ENST00000409544 NM_001252612.1 1800 gAc/gGc 0 +ZNF645 UCSF GRCh37 X 22291335 22291335 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P01_Rec Untested WXS Illumina HiSeq 19 0 ENST00000323684.1:c.227del p.Ala76ValfsTer26 p.A76Vfs*26 ENST00000323684 NM_152577.3 76 gCt/gt 0 +ZNF646 UCSF GRCh37 16 31089358 31089358 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 30 18 34 0 ENST00000300850.5:c.1713G>A p.Lys571= p.K571= ENST00000300850 NM_014699.3 571 aaG/aaA 0 +ZNF658 UCSF GRCh37 9 40773337 40773337 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.145,1000g2011may_all_0.2772,snp132_rs72624049 P01_Rec Untested WXS Illumina HiSeq 142 25 195 0 ENST00000602553.1:c.1938G>A p.Lys646= p.K646= ENST00000602553 646 aaG/aaA 0 +ZNF665 UCSF GRCh37 19 53669476 53669476 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 32 55 120 0 ENST00000396424.3:c.267G>A p.Gln89= p.Q89= ENST00000396424 NM_024733.3 89 caG/caA 0 +ZNF671 UCSF GRCh37 19 58232498 58232498 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 13 54 117 0 ENST00000317398.6:c.956G>A p.Gly319Glu p.G319E ENST00000317398 NM_024833.2 319 gGg/gAg 0 +ZNF680 UCSF GRCh37 7 63981939 63981939 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 128 21 125 0 ENST00000309683.6:c.1193G>A p.Arg398Lys p.R398K ENST00000309683 NM_178558.4 398 aGa/aAa 0 +ZNF687 UCSF GRCh37 1 151259011 151259011 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 40 5 46 0 ENST00000324048.5:c.244G>A p.Val82Ile p.V82I ENST00000324048 82 Gtc/Atc 0 +ZNF750 UCSF GRCh37 17 80790041 80790041 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 82 10 87 0 ENST00000269394.3:c.290C>T p.Ala97Val p.A97V ENST00000269394 NM_024702.2 97 gCc/gTc 0 +ZNF773 UCSF GRCh37 19 58017913 58017913 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 36 6 56 0 ENST00000282292.4:c.450G>A p.Arg150= p.R150= ENST00000282292 NM_198542.1 150 agG/agA 0 +ZNF789 UCSF GRCh37 7 99074104 99074104 + splice_donor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 3 15 0 ENST00000331410.5:c.24+1G>A p.X8_splice ENST00000331410 NM_213603.2 0 +ZNF804A UCSF GRCh37 2 185800689 185800689 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 76 10 90 0 ENST00000302277.6:c.566G>A p.Ser189Asn p.S189N ENST00000302277 NM_194250.1 189 aGt/aAt 0 +ZNF81 UCSF GRCh37 X 47755295 47755295 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 3 11 0 ENST00000376954.1:c.233G>A p.Gly78Glu p.G78E ENST00000376954 78 gGg/gAg 0 +ZNF90 UCSF GRCh37 19 20229997 20229997 + missense_variant Missense_Mutation SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 102 49 114 0 ENST00000418063.2:c.1634C>T p.Ala545Val p.A545V ENST00000418063 NM_007138.1 545 gCc/gTc 0 +ZNF90 UCSF GRCh37 19 20228589 20228589 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 59 32 117 0 ENST00000418063.2:c.227-1G>A p.X76_splice ENST00000418063 NM_007138.1 0 +ZNFX1 UCSF GRCh37 20 47865631 47865631 + synonymous_variant Silent SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 56 7 45 0 ENST00000396105.1:c.3930C>T p.Asp1310= p.D1310= ENST00000396105 NM_021035.2 1310 gaC/gaT 0 +ZNRF3 UCSF GRCh37 22 29446120 29446120 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 15 15 24 0 ENST00000544604.2:c.1951G>A p.Ala651Thr p.A651T ENST00000544604 NM_001206998.1 651 Gcc/Acc 0 +ZNRF4 UCSF GRCh37 19 5455737 5455737 + missense_variant Missense_Mutation SNP G G A NOVEL P01_Rec Untested WXS Illumina HiSeq 14 4 18 0 ENST00000222033.4:c.235G>A p.Ala79Thr p.A79T ENST00000222033 NM_181710.3 79 Gcc/Acc 0 +ZWILCH UCSF GRCh37 15 66806367 66806367 + synonymous_variant Silent SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 65 10 59 0 ENST00000307897.5:c.147C>T p.Asn49= p.N49= ENST00000307897 NM_017975.3 49 aaC/aaT 0 +ZZEF1 UCSF GRCh37 17 3999274 3999274 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P01_Rec Untested WXS Illumina HiSeq 49 6 52 0 ENST00000381638.2:c.1765-1G>A p.X589_splice ENST00000381638 NM_015113.3 0 +ANKRA2 UCSF GRCh37 5 72858699 72858699 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Pri Untested WXS Illumina HiSeq 70 8 89 0 ENST00000296785.3:c.8C>A p.Thr3Lys p.T3K ENST00000296785 NM_023039.4 3 aCa/aAa 0 +ARID1A UCSF GRCh37 1 27106658 27106658 + missense_variant Missense_Mutation SNP A A G NOVEL P02_Pri somatic WXS Sanger Illumina HiSeq 34 13 97 0 ENST00000324856.7:c.6269A>G p.His2090Arg p.H2090R ENST00000324856 NM_006015.4 2090 cAc/cGc 0 +C7orf70 UCSF GRCh37 7 6370158 6370158 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 114 18 195 1 ENST00000313324.4:c.628C>T p.Arg210Cys p.R210C ENST00000313324 NM_001037163.1 210 Cgc/Tgc 0 +CCDC168 UCSF GRCh37 13 103381996 103381996 + frameshift_variant Frame_Shift_Del DEL A A - snp132_rs34874700 P02_Pri Untested WXS Illumina HiSeq 6 0 ENST00000322527.2:c.7164delT p.Phe2388LeufsTer25 p.F2388Lfs*25 ENST00000322527 NM_001146197.1 2388 ttT/tt 0 +CYLC2 UCSF GRCh37 9 105767104 105767104 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 27 21 45 0 ENST00000374798.3:c.308G>A p.Arg103His p.R103H ENST00000374798 NM_001340.3 103 cGt/cAt 0 +E2F8 UCSF GRCh37 11 19252368 19252368 + synonymous_variant Silent SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 36 20 48 0 ENST00000527884.1:c.1080C>T p.Val360= p.V360= ENST00000527884 NM_001256372.1 360 gtC/gtT 0 +EPS8L3 UCSF GRCh37 1 110293388 110293388 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.0085 P02_Pri Untested WXS Illumina HiSeq 8 6 17 0 ENST00000369805.3:c.1667C>T p.Thr556Met p.T556M ENST00000369805 NM_139053.2 556 aCg/aTg 0 +FAM149A UCSF GRCh37 4 187084645 187084645 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 21 6 36 0 ENST00000227065.4:c.901G>A p.Gly301Arg p.G301R ENST00000227065 NM_015398.2 301 Gga/Aga 0 +FAM171A1 UCSF GRCh37 10 15296788 15296788 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Pri Untested WXS Illumina HiSeq 19 12 55 0 ENST00000378116.4:c.509C>T p.Thr170Met p.T170M ENST00000378116 NM_001010924.1 170 aCg/aTg 0 +GATA6 UCSF GRCh37 18 19761487 19761487 + missense_variant Missense_Mutation SNP C C A NOVEL P02_Pri Untested WXS Illumina HiSeq 35 5 52 0 ENST00000269216.3:c.1376C>A p.Ala459Asp p.A459D ENST00000269216 NM_005257.4 459 gCc/gAc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Pri Untested WXS Illumina HiSeq 29 35 77 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LAMB3 UCSF GRCh37 1 209805972 209805972 + missense_variant Missense_Mutation SNP C C T snp132_rs113063967 P02_Pri Untested WXS Illumina HiSeq 15 7 19 0 ENST00000391911.1:c.778G>A p.Ala260Thr p.A260T ENST00000391911 NM_001017402.1 260 Gca/Aca 0 +LRRC37A3 UCSF GRCh37 17 62856876 62856876 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.005,1000g2011may_all_0.0139,snp132_rs77916588 P02_Pri Untested WXS Illumina HiSeq 125 43 218 0 ENST00000584306.1:c.3388G>A p.Val1130Ile p.V1130I ENST00000584306 NM_199340.2 1130 Gtt/Att 0 +NEURL UCSF GRCh37 10 105349981 105349981 + missense_variant Missense_Mutation SNP A A C NOVEL P02_Pri Untested WXS Illumina HiSeq 15 13 47 0 ENST00000369780.4:c.1577A>C p.Glu526Ala p.E526A ENST00000369780 NM_004210.4 526 gAa/gCa 0 +OGT UCSF GRCh37 X 70787552 70787552 + missense_variant Missense_Mutation SNP C C A NOVEL P02_Pri Untested WXS Illumina HiSeq 12 12 60 0 ENST00000373719.3:c.2792C>A p.Thr931Asn p.T931N ENST00000373719 NM_181673.2 931 aCc/aAc 0 +RBBP7 UCSF GRCh37 X 16881197 16881197 + missense_variant Missense_Mutation SNP T T A NOVEL P02_Pri Untested WXS Illumina HiSeq 37 29 85 0 ENST00000380084.4:c.320A>T p.His107Leu p.H107L ENST00000380084 NM_001198719.1 107 cAt/cTt 0 +RHPN2 UCSF GRCh37 19 33490566 33490566 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.110,snp132_rs74582927 P02_Pri Untested WXS Illumina HiSeq 21 5 35 0 ENST00000254260.3:c.1151A>G p.Gln384Arg p.Q384R ENST00000254260 NM_033103.4 384 cAg/cGg 0 +SERPINB12 UCSF GRCh37 18 61228397 61228397 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Pri Untested WXS Illumina HiSeq 75 26 104 0 ENST00000269491.1:c.464G>T p.Arg155Ile p.R155I ENST00000269491 NM_080474.1 155 aGa/aTa 0 +SLC39A12 UCSF GRCh37 10 18250713 18250713 + synonymous_variant Silent SNP T T C NOVEL P02_Pri Untested WXS Illumina HiSeq 58 19 94 0 ENST00000377369.2:c.465T>C p.Asp155= p.D155= ENST00000377369 NM_001145195.1 155 gaT/gaC 0 +SNCAIP UCSF GRCh37 5 121787259 121787259 + missense_variant Missense_Mutation SNP A A C NOVEL P02_Pri Untested WXS Illumina HiSeq 47 14 96 0 ENST00000261368.8:c.2717A>C p.Asn906Thr p.N906T ENST00000261368 NM_005460.2 906 aAc/aCc 0 +SPIC UCSF GRCh37 12 101880272 101880272 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Pri Untested WXS Illumina HiSeq 100 35 131 0 ENST00000551346.1:c.470G>T p.Arg157Ile p.R157I ENST00000551346 157 aGa/aTa 0 +TP53 UCSF GRCh37 17 7578370 7578370 + splice_donor_variant Splice_Site SNP C C T NOVEL P02_Pri somatic WXS Sanger Illumina HiSeq 2 14 21 0 ENST00000269305.4:c.559+1G>A p.X187_splice ENST00000269305 NM_001126112.2 0 +TPTE2 UCSF GRCh37 13 20006639 20006639 + missense_variant Missense_Mutation SNP T T A NOVEL P02_Pri Untested WXS Illumina HiSeq 96 12 90 1 ENST00000400230.2:c.1196A>T p.Lys399Ile p.K399I ENST00000400230 399 aAa/aTa 0 +TRAPPC10 UCSF GRCh37 21 45502963 45502963 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Pri Untested WXS Illumina HiSeq 35 27 92 0 ENST00000291574.4:c.2018C>T p.Ala673Val p.A673V ENST00000291574 NM_003274.4 673 gCg/gTg 0 +ZNF521 UCSF GRCh37 18 22804622 22804622 + missense_variant Missense_Mutation SNP C C G NOVEL P02_Pri Untested WXS Illumina HiSeq 43 5 69 1 ENST00000361524.3:c.3260G>C p.Gly1087Ala p.G1087A ENST00000361524 NM_015461.2 1087 gGc/gCc 0 +ZNF676 UCSF GRCh37 19 22364067 22364090 + inframe_deletion In_Frame_Del DEL CAAAATGATCTGACATATTCTTTA CAAAATGATCTGACATATTCTTTA - NOVEL P02_Pri Untested WXS Illumina HiSeq 6 0 ENST00000397121.2:c.429_452del p.Lys144_Cys151del p.K144_C151del ENST00000397121 NM_001001411.2 143 tgTAAAGAATATGTCAGATCATTTTGc/tgc 0 +ARID1A UCSF GRCh37 1 27106658 27106658 + missense_variant Missense_Mutation SNP A A G NOVEL P02_Rec somatic WXS Sanger Illumina HiSeq 87 13 97 0 ENST00000324856.7:c.6269A>G p.His2090Arg p.H2090R ENST00000324856 NM_006015.4 2090 cAc/cGc 0 +CEP350 UCSF GRCh37 1 180022947 180022948 + frameshift_variant Frame_Shift_Ins INS - - TCGACAGTATATGAAAGAGGAAGAAA NOVEL P02_Rec Untested WXS Illumina HiSeq 11 0 ENST00000367607.3:c.5052_5053insTCGACAGTATATGAAAGAGGAAGAAA p.Arg1685SerfsTer13 p.R1685Sfs*13 ENST00000367607 NM_014810.4 1684 -/TCGACAGTATATGAAAGAGGAAGAAA 0 +CYLC2 UCSF GRCh37 9 105767104 105767104 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 35 34 45 0 ENST00000374798.3:c.308G>A p.Arg103His p.R103H ENST00000374798 NM_001340.3 103 cGt/cAt 0 +E2F8 UCSF GRCh37 11 19252368 19252368 + synonymous_variant Silent SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 36 21 48 0 ENST00000527884.1:c.1080C>T p.Val360= p.V360= ENST00000527884 NM_001256372.1 360 gtC/gtT 0 +EPS8L3 UCSF GRCh37 1 110293388 110293388 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.0085 P02_Rec Untested WXS Illumina HiSeq 23 20 17 0 ENST00000369805.3:c.1667C>T p.Thr556Met p.T556M ENST00000369805 NM_139053.2 556 aCg/aTg 0 +FAM171A1 UCSF GRCh37 10 15296788 15296788 + missense_variant Missense_Mutation SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 41 15 55 0 ENST00000378116.4:c.509C>T p.Thr170Met p.T170M ENST00000378116 NM_001010924.1 170 aCg/aTg 0 +FCGBP UCSF GRCh37 19 40368330 40368330 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.124,1000g2011may_all_0.2035,snp132_rs74540349 P02_Rec Untested WXS Illumina HiSeq 72 8 47 1 ENST00000221347.6:c.13018G>A p.Glu4340Lys p.E4340K ENST00000221347 NM_003890.2 4340 Gaa/Aaa 0 +GGT1 UCSF GRCh37 22 25011077 25011077 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 19 4 24 0 ENST00000400382.1:c.365C>T p.Ser122Leu p.S122L ENST00000400382 NM_001288833.1 122 tCg/tTg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 55 40 77 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LAMB3 UCSF GRCh37 1 209805972 209805972 + missense_variant Missense_Mutation SNP C C T snp132_rs113063967 P02_Rec Untested WXS Illumina HiSeq 18 8 19 0 ENST00000391911.1:c.778G>A p.Ala260Thr p.A260T ENST00000391911 NM_001017402.1 260 Gca/Aca 0 +LRP4 UCSF GRCh37 11 46898772 46898772 + synonymous_variant Silent SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 70 11 70 0 ENST00000378623.1:c.3255C>T p.Ala1085= p.A1085= ENST00000378623 NM_002334.3 1085 gcC/gcT 0 +LRRC37A3 UCSF GRCh37 17 62856876 62856876 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.005,1000g2011may_all_0.0139,snp132_rs77916588 P02_Rec Untested WXS Illumina HiSeq 206 29 218 0 ENST00000584306.1:c.3388G>A p.Val1130Ile p.V1130I ENST00000584306 NM_199340.2 1130 Gtt/Att 0 +MMRN1 UCSF GRCh37 4 90874492 90874492 + stop_gained Nonsense_Mutation SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 85 16 103 0 ENST00000394980.1:c.3610C>T p.Arg1204Ter p.R1204* ENST00000394980 1204 Cga/Tga 0 +NEURL UCSF GRCh37 10 105349981 105349981 + missense_variant Missense_Mutation SNP A A C NOVEL P02_Rec Untested WXS Illumina HiSeq 35 17 47 0 ENST00000369780.4:c.1577A>C p.Glu526Ala p.E526A ENST00000369780 NM_004210.4 526 gAa/gCa 0 +NPC1L1 UCSF GRCh37 7 44578793 44578793 + synonymous_variant Silent SNP G G A NOVEL P02_Rec Untested WXS Illumina HiSeq 79 9 79 0 ENST00000289547.4:c.1203C>T p.Phe401= p.F401= ENST00000289547 NM_013389.2 401 ttC/ttT 0 +OGT UCSF GRCh37 X 70787552 70787552 + missense_variant Missense_Mutation SNP C C A NOVEL P02_Rec Untested WXS Illumina HiSeq 21 12 60 0 ENST00000373719.3:c.2792C>A p.Thr931Asn p.T931N ENST00000373719 NM_181673.2 931 aCc/aAc 0 +PTPRM UCSF GRCh37 18 8244164 8244164 + synonymous_variant Silent SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 103 14 85 0 ENST00000580170.1:c.2409C>T p.Asp803= p.D803= ENST00000580170 NM_001105244.1 803 gaC/gaT 0 +RBBP7 UCSF GRCh37 X 16881197 16881197 + missense_variant Missense_Mutation SNP T T A NOVEL P02_Rec Untested WXS Illumina HiSeq 82 38 85 0 ENST00000380084.4:c.320A>T p.His107Leu p.H107L ENST00000380084 NM_001198719.1 107 cAt/cTt 0 +SERPINB12 UCSF GRCh37 18 61228397 61228397 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Rec Untested WXS Illumina HiSeq 67 50 104 0 ENST00000269491.1:c.464G>T p.Arg155Ile p.R155I ENST00000269491 NM_080474.1 155 aGa/aTa 0 +SLC39A12 UCSF GRCh37 10 18250713 18250713 + synonymous_variant Silent SNP T T C NOVEL P02_Rec Untested WXS Illumina HiSeq 70 44 94 0 ENST00000377369.2:c.465T>C p.Asp155= p.D155= ENST00000377369 NM_001145195.1 155 gaT/gaC 0 +SPIC UCSF GRCh37 12 101880272 101880272 + missense_variant Missense_Mutation SNP G G T NOVEL P02_Rec Untested WXS Illumina HiSeq 72 58 131 0 ENST00000551346.1:c.470G>T p.Arg157Ile p.R157I ENST00000551346 157 aGa/aTa 0 +TP53 UCSF GRCh37 17 7578370 7578370 + splice_donor_variant Splice_Site SNP C C T NOVEL P02_Rec somatic WXS Sanger Illumina HiSeq 4 39 21 0 ENST00000269305.4:c.559+1G>A p.X187_splice ENST00000269305 NM_001126112.2 0 +TRAPPC10 UCSF GRCh37 21 45502963 45502963 + missense_variant Missense_Mutation SNP C C T NOVEL P02_Rec Untested WXS Illumina HiSeq 45 45 92 0 ENST00000291574.4:c.2018C>T p.Ala673Val p.A673V ENST00000291574 NM_003274.4 673 gCg/gTg 0 +WDR33 UCSF GRCh37 2 128463940 128463940 + missense_variant Missense_Mutation SNP G G C NOVEL P02_Rec Untested WXS Illumina HiSeq 107 15 101 0 ENST00000322313.4:c.3968C>G p.Pro1323Arg p.P1323R ENST00000322313 NM_018383.4 1323 cCg/cGg 0 +ZNF676 UCSF GRCh37 19 22364067 22364090 + inframe_deletion In_Frame_Del DEL CAAAATGATCTGACATATTCTTTA CAAAATGATCTGACATATTCTTTA - NOVEL P02_Rec Untested WXS Illumina HiSeq 9 0 ENST00000397121.2:c.429_452del p.Lys144_Cys151del p.K144_C151del ENST00000397121 NM_001001411.2 143 tgTAAAGAATATGTCAGATCATTTTGc/tgc 0 +ZNF676 UCSF GRCh37 19 22364102 22364146 + inframe_deletion In_Frame_Del DEL TTTCTCTCCAGTATGCCTTATCTTATGTCTGTTTGAATTTGAACA TTTCTCTCCAGTATGCCTTATCTTATGTCTGTTTGAATTTGAACA - NOVEL P02_Rec Untested WXS Illumina HiSeq 7 0 ENST00000397121.2:c.373_417del p.Cys125_Lys139del p.C125_K139del ENST00000397121 NM_001001411.2 125 TGTTCAAATTCAAACAGACATAAGATAAGGCATACTGGAGAGAAA/- 0 +ACSF2 UCSF GRCh37 17 48541208 48541208 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Pri Untested WXS Illumina HiSeq 66 31 102 0 ENST00000300441.4:c.1076T>G p.Met359Arg p.M359R ENST00000300441 NM_025149.4 359 aTg/aGg 0 +BOD1L UCSF GRCh37 4 13604659 13604659 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Pri Untested WXS Illumina HiSeq 139 76 170 0 ENST00000040738.5:c.3865G>A p.Val1289Ile p.V1289I ENST00000040738 NM_148894.2 1289 Gtt/Att 0 +CAND2 UCSF GRCh37 3 12858462 12858462 + synonymous_variant Silent SNP C C T NOVEL P04_Pri somatic WXS Sanger Illumina HiSeq 33 25 61 1 ENST00000456430.2:c.2031C>T p.Asp677= p.D677= ENST00000456430 NM_001162499.1 677 gaC/gaT 0 +CDH7 UCSF GRCh37 18 63481815 63481815 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.013,1000g2011may_all_0.0353,snp132_rs17075245 P04_Pri Untested WXS Illumina HiSeq 110 54 141 0 ENST00000397968.2:c.600G>A p.Pro200= p.P200= ENST00000397968 NM_004361.2 200 ccG/ccA 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Pri Untested WXS Illumina HiSeq 75 46 91 0 ENST00000345146.2:c.394C>T p.Arg132Cys p.R132C ENST00000345146 NM_005896.2 132 Cgt/Tgt 0 +MUC4 UCSF GRCh37 3 195506723 195506770 + inframe_deletion In_Frame_Del DEL TGTCGGTGACAGGAAGAGGGGTGGCGTGACGTGTGGATGCTGAGGAAG TGTCGGTGACAGGAAGAGGGGTGGCGTGACGTGTGGATGCTGAGGAAG - NOVEL P04_Pri Untested WXS Illumina HiSeq 8 0 ENST00000463781.3:c.11691_11738del p.Arg3900_Thr3915del p.R3900_T3915del ENST00000463781 NM_018406.6 3894 aCTTCCTCAGCATCCACACGTCACGCCACCCCTCTTCCTGTCACCGACAct/act 0 +OR10V1 UCSF GRCh37 11 59480502 59480502 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Pri Untested WXS Illumina HiSeq 83 44 124 0 ENST00000307552.2:c.817C>T p.Arg273Trp p.R273W ENST00000307552 NM_001005324.1 273 Cgg/Tgg 0 +PSAPL1 UCSF GRCh37 4 7435803 7435803 + synonymous_variant Silent SNP G G A NOVEL P04_Pri somatic WXS Sanger Illumina HiSeq 101 42 122 0 ENST00000319098.4:c.804C>T p.Ala268= p.A268= ENST00000319098 NM_001085382.1 268 gcC/gcT 0 +RYR1 UCSF GRCh37 19 38939100 38939100 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.005,1000g2011may_all_0.0263 P04_Pri somatic WXS Sanger Illumina HiSeq 111 67 128 0 ENST00000359596.3:c.906C>T p.Asp302= p.D302= ENST00000359596 302 gaC/gaT 0 +SGK223 UCSF GRCh37 8 8234869 8234870 + inframe_insertion In_Frame_Ins INS - - GCCGCT snp132_rs35972623 P04_Pri Untested WXS Illumina HiSeq 7 0 ENST00000520004.1:c.1049_1050insAGCGGC p.Ala351_Ser352insAlaAla p.A351_S352insAA ENST00000520004 350 ggc/ggAGCGGCc 0 +SLC9A4 UCSF GRCh37 2 103148842 103148842 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Pri Untested WXS Illumina HiSeq 78 36 142 0 ENST00000295269.4:c.2092C>T p.Arg698Trp p.R698W ENST00000295269 NM_001011552.3 698 Cgg/Tgg 0 +TEAD3 UCSF GRCh37 6 35454288 35454288 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Pri Untested WXS Illumina HiSeq 41 21 51 0 ENST00000338863.7:c.152C>T p.Pro51Leu p.P51L ENST00000338863 NM_003214.3 51 cCg/cTg 0 +TERF2IP UCSF GRCh37 16 75690462 75690462 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Pri Untested WXS Illumina HiSeq 128 82 160 0 ENST00000300086.4:c.1153T>C p.Phe385Leu p.F385L ENST00000300086 NM_018975.3 385 Ttt/Ctt 0 +TERF2IP UCSF GRCh37 16 75690302 75690302 + synonymous_variant Silent SNP A A C NOVEL P04_Pri Untested WXS Illumina HiSeq 131 83 138 0 ENST00000300086.4:c.993A>C p.Thr331= p.T331= ENST00000300086 NM_018975.3 331 acA/acC 0 +TP53 UCSF GRCh37 17 7577538 7577538 + missense_variant Missense_Mutation SNP C C T snp132_rs11540652 P04_Pri somatic WXS Sanger Illumina HiSeq 24 54 41 0 ENST00000269305.4:c.743G>A p.Arg248Gln p.R248Q ENST00000269305 NM_001126112.2 248 cGg/cAg 0 +WDFY4 UCSF GRCh37 10 50004488 50004488 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Pri Untested WXS Illumina HiSeq 116 50 143 0 ENST00000325239.5:c.4403A>G p.Asn1468Ser p.N1468S ENST00000325239 NM_020945.1 1468 aAt/aGt 0 +ZNF107 UCSF GRCh37 7 64167377 64167377 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Pri Untested WXS Illumina HiSeq 97 45 128 0 ENST00000395391.1:c.695C>G p.Thr232Ser p.T232S ENST00000395391 232 aCt/aGt 0 +ACSF2 UCSF GRCh37 17 48541208 48541208 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 46 40 102 0 ENST00000300441.4:c.1076T>G p.Met359Arg p.M359R ENST00000300441 NM_025149.4 359 aTg/aGg 0 +ADAM17 UCSF GRCh37 2 9630335 9630335 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 77 16 75 0 ENST00000310823.3:c.2446C>T p.Arg816Cys p.R816C ENST00000310823 NM_003183.4 816 Cgt/Tgt 0 +ADAM29 UCSF GRCh37 4 175898766 175898766 + missense_variant Missense_Mutation SNP T T A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 117 27 111 0 ENST00000359240.3:c.2090T>A p.Leu697His p.L697H ENST00000359240 NM_014269.4 697 cTt/cAt 0 +APOPT1 UCSF GRCh37 14 104040439 104040465 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TTAAGGAAAAAGAAGAATTTATTCACT TTAAGGAAAAAGAAGAATTTATTCACT AAGGAAAAAGAAGAATTTTTTAACC NOVEL P04_Rec1 Untested WXS Illumina HiSeq 6 0 ENST00000409074.2:c.361-5_382delinsAAGGAAAAAGAAGAATTTTTTAACC p.X121_splice ENST00000409074 NM_032374.3 0 +ATXN2L UCSF GRCh37 16 28840741 28840741 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 70 17 82 0 ENST00000395547.2:c.761A>G p.Asn254Ser p.N254S ENST00000395547 NM_148414.2 254 aAt/aGt 0 +BOD1L UCSF GRCh37 4 13604659 13604659 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec1 Untested WXS Illumina HiSeq 151 111 170 0 ENST00000040738.5:c.3865G>A p.Val1289Ile p.V1289I ENST00000040738 NM_148894.2 1289 Gtt/Att 0 +C5orf54 UCSF GRCh37 5 159822214 159822214 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 186 21 168 0 ENST00000408953.3:c.284C>T p.Ser95Leu p.S95L ENST00000408953 NM_022090.3 95 tCg/tTg 0 +C6orf201 UCSF GRCh37 6 4087953 4087953 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 121 165 123 0 ENST00000380175.4:c.78G>C p.Lys26Asn p.K26N ENST00000380175 NM_001085401.2 26 aaG/aaC 0 +CDH7 UCSF GRCh37 18 63481815 63481815 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.013,1000g2011may_all_0.0353,snp132_rs17075245 P04_Rec1 Untested WXS Illumina HiSeq 111 82 141 0 ENST00000397968.2:c.600G>A p.Pro200= p.P200= ENST00000397968 NM_004361.2 200 ccG/ccA 0 +CYP2C9 UCSF GRCh37 10 96702051 96702051 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 90 56 121 0 ENST00000260682.6:c.434T>C p.Val145Ala p.V145A ENST00000260682 NM_000771.3 145 gTt/gCt 0 +DEFB126 UCSF GRCh37 20 126310 126311 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P04_Rec1 Untested WXS Illumina HiSeq 9 0 ENST00000382398.3:c.313_314del p.Thr105ProfsTer? p.T105Pfs*? ENST00000382398 NM_030931.3 105 ACc/c 0 +FAM206A UCSF GRCh37 9 111701942 111701942 + synonymous_variant Silent SNP T T C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 99 63 123 0 ENST00000322940.6:c.522T>C p.Ile174= p.I174= ENST00000322940 NM_017832.3 174 atT/atC 0 +FUT11 UCSF GRCh37 10 75532510 75532510 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 10 6 18 0 ENST00000372841.3:c.419A>G p.Gln140Arg p.Q140R ENST00000372841 NM_173540.2 140 cAg/cGg 0 +HEY2 UCSF GRCh37 6 126080810 126080810 + synonymous_variant Silent SNP C C T NOVEL P04_Rec1 somatic WXS Sanger Illumina HiSeq 65 42 97 0 ENST00000368364.3:c.876C>T p.Asn292= p.N292= ENST00000368364 NM_012259.2 292 aaC/aaT 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 101 61 91 0 ENST00000345146.2:c.394C>T p.Arg132Cys p.R132C ENST00000345146 NM_005896.2 132 Cgt/Tgt 0 +KIAA1731 UCSF GRCh37 11 93432660 93432660 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 223 68 184 0 ENST00000325212.6:c.4582G>C p.Glu1528Gln p.E1528Q ENST00000325212 1528 Gaa/Caa 0 +KRT83 UCSF GRCh37 12 52711478 52711478 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec1 Untested WXS Illumina HiSeq 93 13 88 0 ENST00000293670.3:c.737G>A p.Arg246Gln p.R246Q ENST00000293670 NM_002282.3 246 cGg/cAg 0 +LSG1 UCSF GRCh37 3 194369475 194369475 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 74 56 99 0 ENST00000265245.5:c.1478C>T p.Thr493Met p.T493M ENST00000265245 NM_018385.2 493 aCg/aTg 0 +MACF1 UCSF GRCh37 1 39934319 39934319 + synonymous_variant Silent SNP T T C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 93 26 108 0 ENST00000545844.1:c.15609T>C p.Arg5203= p.R5203= ENST00000545844 5203 cgT/cgC 0 +MGAT4C UCSF GRCh37 12 86373731 86373731 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 141 43 120 0 ENST00000604798.1:c.773G>C p.Gly258Ala p.G258A ENST00000604798 258 gGc/gCc 0 +MRPL55 UCSF GRCh37 1 228295410 228295410 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 31 6 33 2 ENST00000366731.5:c.295A>C p.Thr99Pro p.T99P ENST00000366731 99 Acc/Ccc 0 +MRPS6 UCSF GRCh37 21 35514779 35514779 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec1 Untested WXS Illumina HiSeq 112 16 73 0 ENST00000399312.2:c.257T>C p.Ile86Thr p.I86T ENST00000399312 NM_032476.3 86 aTa/aCa 0 +MUC16 UCSF GRCh37 19 9070009 9070009 + stop_gained Nonsense_Mutation SNP C C A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 137 123 167 0 ENST00000397910.4:c.17437G>T p.Glu5813Ter p.E5813* ENST00000397910 NM_024690.2 5813 Gag/Tag 0 +OR10T2 UCSF GRCh37 1 158368385 158368385 + missense_variant Missense_Mutation SNP C C A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 65 29 88 0 ENST00000334438.1:c.872G>T p.Ser291Ile p.S291I ENST00000334438 NM_001004475.1 291 aGt/aTt 0 +PDZD2 UCSF GRCh37 5 32087897 32087897 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec1 somatic WXS Sanger Illumina HiSeq 36 11 40 0 ENST00000438447.1:c.4343A>G p.Asp1448Gly p.D1448G ENST00000438447 1448 gAc/gGc 0 +PSAPL1 UCSF GRCh37 4 7435803 7435803 + synonymous_variant Silent SNP G G A NOVEL P04_Rec1 somatic WXS Sanger Illumina HiSeq 59 51 122 0 ENST00000319098.4:c.804C>T p.Ala268= p.A268= ENST00000319098 NM_001085382.1 268 gcC/gcT 0 +RAP1GAP2 UCSF GRCh37 17 2909313 2909313 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec1 Untested WXS Illumina HiSeq 80 24 65 0 ENST00000254695.8:c.1337C>T p.Ser446Leu p.S446L ENST00000254695 NM_015085.4 446 tCg/tTg 0 +RIMBP2 UCSF GRCh37 12 130926571 130926571 + synonymous_variant Silent SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 81 16 81 0 ENST00000261655.4:c.1275C>T p.Asn425= p.N425= ENST00000261655 NM_015347.4 425 aaC/aaT 0 +SLC9A4 UCSF GRCh37 2 103148842 103148842 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec1 Untested WXS Illumina HiSeq 81 64 142 0 ENST00000295269.4:c.2092C>T p.Arg698Trp p.R698W ENST00000295269 NM_001011552.3 698 Cgg/Tgg 0 +SPATA6 UCSF GRCh37 1 48764545 48764545 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 156 43 126 0 ENST00000371847.3:c.1307G>C p.Gly436Ala p.G436A ENST00000371847 NM_019073.2 436 gGc/gCc 0 +TDG UCSF GRCh37 12 104373729 104373730 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 9 0 ENST00000392872.3:c.292dup p.Ile98AsnfsTer6 p.I98Nfs*6 ENST00000392872 NM_003211.4 96 gaa/gaAa 0 +TEAD3 UCSF GRCh37 6 35454288 35454288 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec1 Untested WXS Illumina HiSeq 28 40 51 0 ENST00000338863.7:c.152C>T p.Pro51Leu p.P51L ENST00000338863 NM_003214.3 51 cCg/cTg 0 +TP53 UCSF GRCh37 17 7577538 7577538 + missense_variant Missense_Mutation SNP C C T snp132_rs11540652 P04_Rec1 somatic WXS Sanger Illumina HiSeq 5 58 41 0 ENST00000269305.4:c.743G>A p.Arg248Gln p.R248Q ENST00000269305 NM_001126112.2 248 cGg/cAg 0 +ZNF107 UCSF GRCh37 7 64167377 64167377 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec1 Untested WXS Illumina HiSeq 109 50 128 0 ENST00000395391.1:c.695C>G p.Thr232Ser p.T232S ENST00000395391 232 aCt/aGt 0 +ACSF2 UCSF GRCh37 17 48541208 48541208 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Rec2 Untested WXS Illumina HiSeq 38 27 102 0 ENST00000300441.4:c.1076T>G p.Met359Arg p.M359R ENST00000300441 NM_025149.4 359 aTg/aGg 0 +APOBEC4 UCSF GRCh37 1 183617696 183617696 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec2 somatic WXS Sanger Illumina HiSeq 91 54 145 0 ENST00000308641.4:c.221C>G p.Ser74Cys p.S74C ENST00000308641 NM_203454.2 74 tCt/tGt 0 +BOD1L UCSF GRCh37 4 13604659 13604659 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 71 62 170 0 ENST00000040738.5:c.3865G>A p.Val1289Ile p.V1289I ENST00000040738 NM_148894.2 1289 Gtt/Att 0 +CDH7 UCSF GRCh37 18 63481815 63481815 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.013,1000g2011may_all_0.0353,snp132_rs17075245 P04_Rec2 Untested WXS Illumina HiSeq 66 49 141 0 ENST00000397968.2:c.600G>A p.Pro200= p.P200= ENST00000397968 NM_004361.2 200 ccG/ccA 0 +CFH UCSF GRCh37 1 196694259 196694259 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec2 Untested WXS Illumina HiSeq 70 44 95 0 ENST00000367429.4:c.1705T>C p.Cys569Arg p.C569R ENST00000367429 NM_000186.3 569 Tgc/Cgc 0 +CLASP1 UCSF GRCh37 2 122182732 122182732 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec2 Untested WXS Illumina HiSeq 59 62 135 0 ENST00000263710.4:c.2195C>G p.Pro732Arg p.P732R ENST00000263710 NM_015282.2 732 cCa/cGa 0 +COL13A1 UCSF GRCh37 10 71684757 71684757 + synonymous_variant Silent SNP C C T NOVEL P04_Rec2 somatic WXS Sanger Illumina HiSeq 18 8 25 0 ENST00000398978.3:c.1290C>T p.Gly430= p.G430= ENST00000398978 NM_001130103.1 430 ggC/ggT 0 +DPYSL4 UCSF GRCh37 10 134006219 134006219 + synonymous_variant Silent SNP C C G NOVEL P04_Rec2 Untested WXS Illumina HiSeq 54 23 95 0 ENST00000338492.4:c.186C>G p.Gly62= p.G62= ENST00000338492 NM_006426.2 62 ggC/ggG 0 +GABRE UCSF GRCh37 X 151123975 151123975 + synonymous_variant Silent SNP G G A NOVEL P04_Rec2 somatic WXS Sanger Illumina HiSeq 8 58 71 0 ENST00000370328.3:c.1002C>T p.Val334= p.V334= ENST00000370328 NM_004961.3 334 gtC/gtT 0 +GPR112 UCSF GRCh37 X 135453557 135453557 + missense_variant Missense_Mutation SNP G G T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 5 42 51 0 ENST00000394143.1:c.7467G>T p.Glu2489Asp p.E2489D ENST00000394143 NM_153834.3 2489 gaG/gaT 0 +GULP1 UCSF GRCh37 2 189449083 189449083 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec2 Untested WXS Illumina HiSeq 84 52 131 0 ENST00000409580.1:c.701G>A p.Arg234His p.R234H ENST00000409580 234 cGc/cAc 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec2 Untested WXS Illumina HiSeq 61 38 91 0 ENST00000345146.2:c.394C>T p.Arg132Cys p.R132C ENST00000345146 NM_005896.2 132 Cgt/Tgt 0 +LAMA3 UCSF GRCh37 18 21484018 21484018 + missense_variant Missense_Mutation SNP G G T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 60 44 126 0 ENST00000313654.9:c.6440G>T p.Arg2147Leu p.R2147L ENST00000313654 NM_198129.1 2147 cGg/cTg 0 +PHRF1 UCSF GRCh37 11 587424 587424 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec2 Untested WXS Illumina HiSeq 38 49 99 0 ENST00000416188.2:c.380C>G p.Ala127Gly p.A127G ENST00000416188 127 gCc/gGc 0 +PSAP UCSF GRCh37 10 73579333 73579334 + frameshift_variant Frame_Shift_Ins INS - - CTTG NOVEL P04_Rec2 Untested WXS Illumina HiSeq 18 0 ENST00000394936.3:c.1238_1239insCAAG p.Lys413AsnfsTer26 p.K413Nfs*26 ENST00000394936 413 aag/aaCAAGg 0 +SLC9A4 UCSF GRCh37 2 103148842 103148842 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 52 33 142 0 ENST00000295269.4:c.2092C>T p.Arg698Trp p.R698W ENST00000295269 NM_001011552.3 698 Cgg/Tgg 0 +SLCO1B7 UCSF GRCh37 12 21200142 21200142 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P04_Rec2 Untested WXS Illumina HiSeq 41 0 ENST00000421593.2:c.989del p.Leu330CysfsTer28 p.L330Cfs*28 ENST00000421593 NM_001009562.4 329 Ttt/tt 0 +SNRPB UCSF GRCh37 20 2443747 2443747 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 39 38 103 0 ENST00000438552.2:c.547G>A p.Ala183Thr p.A183T ENST00000438552 NM_198216.1 183 Gca/Aca 0 +SPIRE1 UCSF GRCh37 18 12449679 12449679 + synonymous_variant Silent SNP G G C NOVEL P04_Rec2 somatic WXS Sanger Illumina HiSeq 29 29 96 0 ENST00000409402.4:c.2229C>G p.Pro743= p.P743= ENST00000409402 NM_001128626.1 743 ccC/ccG 0 +TEAD3 UCSF GRCh37 6 35454288 35454288 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec2 Untested WXS Illumina HiSeq 23 14 51 0 ENST00000338863.7:c.152C>T p.Pro51Leu p.P51L ENST00000338863 NM_003214.3 51 cCg/cTg 0 +TP53 UCSF GRCh37 17 7577538 7577538 + missense_variant Missense_Mutation SNP C C T snp132_rs11540652 P04_Rec2 somatic WXS Sanger Illumina HiSeq 2 28 41 0 ENST00000269305.4:c.743G>A p.Arg248Gln p.R248Q ENST00000269305 NM_001126112.2 248 cGg/cAg 0 +UBQLNL UCSF GRCh37 11 5536309 5536309 + missense_variant Missense_Mutation SNP G G C 1000g2010nov_all_0.027,1000g2011may_all_0.04739,snp132_rs12223282 P04_Rec2 Untested WXS Illumina HiSeq 48 47 133 0 ENST00000380184.1:c.1363C>G p.Gln455Glu p.Q455E ENST00000380184 NM_145053.4 455 Cag/Gag 0 +WDR72 UCSF GRCh37 15 54004993 54004993 + synonymous_variant Silent SNP C C T NOVEL P04_Rec2 Untested WXS Illumina HiSeq 55 43 93 0 ENST00000396328.1:c.687G>A p.Leu229= p.L229= ENST00000396328 NM_182758.3 229 ttG/ttA 0 +ZNF107 UCSF GRCh37 7 64167377 64167377 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec2 Untested WXS Illumina HiSeq 70 40 128 0 ENST00000395391.1:c.695C>G p.Thr232Ser p.T232S ENST00000395391 232 aCt/aGt 0 +ACSF2 UCSF GRCh37 17 48541208 48541208 + missense_variant Missense_Mutation SNP T T G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 59 41 102 0 ENST00000300441.4:c.1076T>G p.Met359Arg p.M359R ENST00000300441 NM_025149.4 359 aTg/aGg 0 +AKAP6 UCSF GRCh37 14 33242972 33242973 + protein_altering_variant In_Frame_Ins INS - - GCA NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 0 ENST00000280979.4:c.3461_3462insGCA p.Cys1154delinsTrpHis p.C1154delinsWH ENST00000280979 NM_004274.4 1154 tgc/tgGCAc 0 +AKR1D1 UCSF GRCh37 7 137782608 137782611 + splice_acceptor_variant,intron_variant Splice_Site DEL TCAG TCAG CAC NOVEL P04_Rec3 Untested WXS Illumina HiSeq 7 0 ENST00000242375.3:c.379-4_379-1delinsCAC p.X127_splice ENST00000242375 NM_005989.3 0 +APOBEC4 UCSF GRCh37 1 183617696 183617696 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 89 85 145 0 ENST00000308641.4:c.221C>G p.Ser74Cys p.S74C ENST00000308641 NM_203454.2 74 tCt/tGt 0 +ARHGEF17 UCSF GRCh37 11 73076827 73076827 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 52 11 51 0 ENST00000263674.3:c.5830C>T p.Leu1944Phe p.L1944F ENST00000263674 NM_014786.3 1944 Ctc/Ttc 0 +ATXN3 UCSF GRCh37 14 92555132 92555132 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 41 0 ENST00000393287.5:c.417del p.Pro140GlnfsTer3 p.P140Qfs*3 ENST00000393287 139 ggT/gg 0 +BOD1L UCSF GRCh37 4 13604659 13604659 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 123 106 170 0 ENST00000040738.5:c.3865G>A p.Val1289Ile p.V1289I ENST00000040738 NM_148894.2 1289 Gtt/Att 0 +C1orf124 UCSF GRCh37 1 231488849 231488851 + frameshift_variant Frame_Shift_Del DEL CCC CCC A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 20 0 ENST00000295050.7:c.1212_1214delinsA p.Phe404LeufsTer3 p.F404Lfs*3 ENST00000295050 NM_032018.5 404 ttCCCa/ttAa 0 +C5orf22 UCSF GRCh37 5 31541063 31541064 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 8 0 ENST00000325366.9:c.816_817del p.Tyr272Ter p.Y272* ENST00000325366 NM_018356.2 272 tAC/t 0 +C9orf84 UCSF GRCh37 9 114486071 114486071 + splice_donor_variant Splice_Site SNP C C G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 81 15 50 0 ENST00000374287.3:c.1762+1G>C p.X588_splice ENST00000374287 0 +CASP10 UCSF GRCh37 2 202050641 202050641 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 18 0 ENST00000286186.6:c.144del p.Asn49ThrfsTer23 p.N49Tfs*23 ENST00000286186 NM_032977.3 47 gtC/gt 0 +CCR4 UCSF GRCh37 3 32994946 32994946 + missense_variant Missense_Mutation SNP T T A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 68 15 102 0 ENST00000330953.5:c.32T>A p.Leu11His p.L11H ENST00000330953 NM_005508.4 11 cTc/cAc 0 +CDH7 UCSF GRCh37 18 63481815 63481815 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.013,1000g2011may_all_0.0353,snp132_rs17075245 P04_Rec3 Untested WXS Illumina HiSeq 93 67 141 0 ENST00000397968.2:c.600G>A p.Pro200= p.P200= ENST00000397968 NM_004361.2 200 ccG/ccA 0 +CFH UCSF GRCh37 1 196694259 196694259 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 78 68 95 0 ENST00000367429.4:c.1705T>C p.Cys569Arg p.C569R ENST00000367429 NM_000186.3 569 Tgc/Cgc 0 +CHRM1 UCSF GRCh37 11 62678364 62678364 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 74 12 96 0 ENST00000306960.3:c.209C>G p.Ala70Gly p.A70G ENST00000306960 NM_000738.2 70 gCt/gGt 0 +CLASP1 UCSF GRCh37 2 122182732 122182732 + missense_variant Missense_Mutation SNP G G C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 121 106 135 0 ENST00000263710.4:c.2195C>G p.Pro732Arg p.P732R ENST00000263710 NM_015282.2 732 cCa/cGa 0 +CNKSR3 UCSF GRCh37 6 154763244 154763244 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 70 10 76 0 ENST00000607772.1:c.397G>A p.Ala133Thr p.A133T ENST00000607772 NM_173515.2 133 Gcc/Acc 0 +COL13A1 UCSF GRCh37 10 71684757 71684757 + synonymous_variant Silent SNP C C T NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 25 13 25 0 ENST00000398978.3:c.1290C>T p.Gly430= p.G430= ENST00000398978 NM_001130103.1 430 ggC/ggT 0 +CRTC2 UCSF GRCh37 1 153921068 153921068 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 95 18 92 0 ENST00000368633.1:c.1727C>T p.Pro576Leu p.P576L ENST00000368633 NM_181715.2 576 cCt/cTt 0 +CUL9 UCSF GRCh37 6 43190286 43190296 + frameshift_variant Frame_Shift_Del DEL GCGGAACCGGG GCGGAACCGGG - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 0 ENST00000252050.4:c.6939_6949del p.Leu2313PhefsTer6 p.L2313Ffs*6 ENST00000252050 NM_015089.2 2313 ttGCGGAACCGGGtg/tttg 0 +DDX60 UCSF GRCh37 4 169215051 169215051 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 118 27 114 0 ENST00000393743.3:c.769T>C p.Ser257Pro p.S257P ENST00000393743 NM_017631.5 257 Tct/Cct 0 +DGKI UCSF GRCh37 7 137172402 137172402 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 271 33 156 0 ENST00000288490.5:c.2336A>G p.Asp779Gly p.D779G ENST00000288490 NM_004717.2 779 gAc/gGc 0 +DPYSL4 UCSF GRCh37 10 134006219 134006219 + synonymous_variant Silent SNP C C G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 72 48 95 0 ENST00000338492.4:c.186C>G p.Gly62= p.G62= ENST00000338492 NM_006426.2 62 ggC/ggG 0 +DUOX1 UCSF GRCh37 15 45431646 45431649 + frameshift_variant Frame_Shift_Del DEL AGTT AGTT - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 15 0 ENST00000321429.4:c.1238_1241del p.Lys413IlefsTer66 p.K413Ifs*66 ENST00000321429 NM_017434.3 413 aAGTTt/at 0 +DYNC2H1 UCSF GRCh37 11 102984845 102984845 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 174 25 141 0 ENST00000398093.3:c.380G>A p.Ser127Asn p.S127N ENST00000398093 127 aGc/aAc 0 +DYNC2LI1 UCSF GRCh37 2 44021791 44021791 + intron_variant Intron DEL C C - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 34 0 ENST00000260605.8:c.507+9del *169* ENST00000260605 NM_001193464.1 0 +ERC1 UCSF GRCh37 12 1192504 1192504 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 15 0 ENST00000397203.2:c.846del p.Leu283PhefsTer20 p.L283Ffs*20 ENST00000397203 282 Ttt/tt 0 +FAM75D1 UCSF GRCh37 9 84606868 84606868 + missense_variant Missense_Mutation SNP C C A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 181 52 170 0 ENST00000344803.2:c.1483C>A p.His495Asn p.H495N ENST00000344803 NM_001001670.2 495 Cat/Aat 0 +FIGNL1 UCSF GRCh37 7 50514933 50514933 + missense_variant Missense_Mutation SNP T T A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 87 21 79 0 ENST00000419119.1:c.53A>T p.Tyr18Phe p.Y18F ENST00000419119 18 tAc/tTc 0 +FIGNL1 UCSF GRCh37 7 50514932 50514932 + synonymous_variant Silent SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 89 21 80 0 ENST00000419119.1:c.54C>T p.Tyr18= p.Y18= ENST00000419119 18 taC/taT 0 +GABRE UCSF GRCh37 X 151123975 151123975 + synonymous_variant Silent SNP G G A NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 9 92 71 0 ENST00000370328.3:c.1002C>T p.Val334= p.V334= ENST00000370328 NM_004961.3 334 gtC/gtT 0 +GLMN UCSF GRCh37 1 92713511 92713511 + synonymous_variant Silent SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 124 26 70 0 ENST00000370360.3:c.1509T>C p.Asn503= p.N503= ENST00000370360 NM_053274.2 503 aaT/aaC 0 +GPR112 UCSF GRCh37 X 135453557 135453557 + missense_variant Missense_Mutation SNP G G T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 52 51 0 ENST00000394143.1:c.7467G>T p.Glu2489Asp p.E2489D ENST00000394143 NM_153834.3 2489 gaG/gaT 0 +GRWD1 UCSF GRCh37 19 48955968 48955968 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 34 13 61 0 ENST00000253237.5:c.1027G>A p.Gly343Ser p.G343S ENST00000253237 NM_031485.3 343 Ggt/Agt 0 +GULP1 UCSF GRCh37 2 189449083 189449083 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 86 62 131 0 ENST00000409580.1:c.701G>A p.Arg234His p.R234H ENST00000409580 234 cGc/cAc 0 +HMBOX1 UCSF GRCh37 8 28827573 28827573 + missense_variant Missense_Mutation SNP A A C NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 138 31 114 0 ENST00000397358.3:c.37A>C p.Met13Leu p.M13L ENST00000397358 NM_024567.3 13 Atg/Ctg 0 +HPS4 UCSF GRCh37 22 26862199 26862199 + missense_variant Missense_Mutation SNP C C A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 84 12 87 0 ENST00000398145.2:c.699G>T p.Gln233His p.Q233H ENST00000398145 NM_022081.5 233 caG/caT 0 +HSP90AB1 UCSF GRCh37 6 44217180 44217180 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 184 21 176 0 ENST00000371554.1:c.214A>G p.Lys72Glu p.K72E ENST00000371554 72 Aaa/Gaa 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 94 62 91 0 ENST00000345146.2:c.394C>T p.Arg132Cys p.R132C ENST00000345146 NM_005896.2 132 Cgt/Tgt 0 +IK UCSF GRCh37 5 140041897 140041897 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 30 0 ENST00000417647.2:c.1660del p.Arg554AspfsTer7 p.R554Dfs*7 ENST00000417647 NM_006083.3 553 Aaa/aa 0 +ITIH5L UCSF GRCh37 X 54785050 54785050 + missense_variant Missense_Mutation SNP A A T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 22 14 31 0 ENST00000218436.6:c.1457T>A p.Val486Asp p.V486D ENST00000218436 NM_198510.2 486 gTt/gAt 0 +KCTD16 UCSF GRCh37 5 143587110 143587110 + splice_donor_variant Splice_Site SNP G G T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 87 12 88 0 ENST00000507359.3:c.832+1G>T p.X278_splice ENST00000507359 NM_020768.3 0 +LAMA3 UCSF GRCh37 18 21484018 21484018 + missense_variant Missense_Mutation SNP G G T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 76 62 126 0 ENST00000313654.9:c.6440G>T p.Arg2147Leu p.R2147L ENST00000313654 NM_198129.1 2147 cGg/cTg 0 +MBD4 UCSF GRCh37 3 129155548 129155548 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 0 ENST00000249910.1:c.939delA p.Glu314LysfsTer4 p.E314Kfs*4 ENST00000249910 313 aaA/aa 0 +MTTP UCSF GRCh37 4 100521799 100521799 + missense_variant Missense_Mutation SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 125 31 125 0 ENST00000457717.1:c.1145A>G p.Lys382Arg p.K382R ENST00000457717 NM_000253.2 382 aAa/aGa 0 +MUC4 UCSF GRCh37 3 195506723 195506770 + inframe_deletion In_Frame_Del DEL TGTCGGTGACAGGAAGAGGGGTGGCGTGACGTGTGGATGCTGAGGAAG TGTCGGTGACAGGAAGAGGGGTGGCGTGACGTGTGGATGCTGAGGAAG - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 8 0 ENST00000463781.3:c.11691_11738del p.Arg3900_Thr3915del p.R3900_T3915del ENST00000463781 NM_018406.6 3894 aCTTCCTCAGCATCCACACGTCACGCCACCCCTCTTCCTGTCACCGACAct/act 0 +MUC5B UCSF GRCh37 11 1253980 1253980 + missense_variant Missense_Mutation SNP A A G 1000g2010nov_all_0.103,snp132_rs115853043 P04_Rec3 Untested WXS Illumina HiSeq 10 4 15 1 ENST00000529681.1:c.2045A>G p.Asp682Gly p.D682G ENST00000529681 NM_002458.2 682 gAc/gGc 0 +PHRF1 UCSF GRCh37 11 587424 587424 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 66 37 99 0 ENST00000416188.2:c.380C>G p.Ala127Gly p.A127G ENST00000416188 127 gCc/gGc 0 +PSAP UCSF GRCh37 10 73579333 73579334 + frameshift_variant Frame_Shift_Ins INS - - CTTG NOVEL P04_Rec3 Untested WXS Illumina HiSeq 32 0 ENST00000394936.3:c.1238_1239insCAAG p.Lys413AsnfsTer26 p.K413Nfs*26 ENST00000394936 413 aag/aaCAAGg 0 +RFC3 UCSF GRCh37 13 34398063 34398063 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 6 0 ENST00000380071.3:c.244delA p.Ile82LeufsTer25 p.I82Lfs*25 ENST00000380071 NM_002915.3 79 Aaa/aa 0 +SH3TC1 UCSF GRCh37 4 8242506 8242509 + frameshift_variant Frame_Shift_Del DEL ATCT ATCT - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 11 0 ENST00000245105.3:c.3836_3839del p.Ile1279ThrfsTer96 p.I1279Tfs*96 ENST00000245105 NM_018986.3 1279 ATCTac/ac 0 +SLC9A4 UCSF GRCh37 2 103148842 103148842 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 91 53 142 0 ENST00000295269.4:c.2092C>T p.Arg698Trp p.R698W ENST00000295269 NM_001011552.3 698 Cgg/Tgg 0 +SLCO1B7 UCSF GRCh37 12 21200142 21200142 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 70 0 ENST00000421593.2:c.989del p.Leu330CysfsTer28 p.L330Cfs*28 ENST00000421593 NM_001009562.4 329 Ttt/tt 0 +SNRPB UCSF GRCh37 20 2443747 2443747 + missense_variant Missense_Mutation SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 65 48 103 0 ENST00000438552.2:c.547G>A p.Ala183Thr p.A183T ENST00000438552 NM_198216.1 183 Gca/Aca 0 +SORCS1 UCSF GRCh37 10 108431048 108431048 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 16 0 ENST00000344440.6:c.2136del p.Tyr712Ter p.Y712* ENST00000344440 NM_001206571.1 712 taT/ta 0 +SPIRE1 UCSF GRCh37 18 12449679 12449679 + synonymous_variant Silent SNP G G C NOVEL P04_Rec3 somatic WXS Sanger Illumina HiSeq 49 49 96 0 ENST00000409402.4:c.2229C>G p.Pro743= p.P743= ENST00000409402 NM_001128626.1 743 ccC/ccG 0 +TEAD3 UCSF GRCh37 6 35454288 35454288 + missense_variant Missense_Mutation SNP G G A NOVEL P04_Rec3 Untested WXS Illumina HiSeq 29 35 51 0 ENST00000338863.7:c.152C>T p.Pro51Leu p.P51L ENST00000338863 NM_003214.3 51 cCg/cTg 0 +TP53 UCSF GRCh37 17 7577538 7577538 + missense_variant Missense_Mutation SNP C C T snp132_rs11540652 P04_Rec3 somatic WXS Sanger Illumina HiSeq 7 43 41 0 ENST00000269305.4:c.743G>A p.Arg248Gln p.R248Q ENST00000269305 NM_001126112.2 248 cGg/cAg 0 +UBQLNL UCSF GRCh37 11 5536309 5536309 + missense_variant Missense_Mutation SNP G G C 1000g2010nov_all_0.027,1000g2011may_all_0.04739,snp132_rs12223282 P04_Rec3 Untested WXS Illumina HiSeq 83 84 133 0 ENST00000380184.1:c.1363C>G p.Gln455Glu p.Q455E ENST00000380184 NM_145053.4 455 Cag/Gag 0 +USP24 UCSF GRCh37 1 55591187 55591187 + synonymous_variant Silent SNP A A G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 210 39 182 0 ENST00000294383.6:c.3766T>C p.Leu1256= p.L1256= ENST00000294383 NM_015306.2 1256 Tta/Cta 0 +WDR72 UCSF GRCh37 15 54004993 54004993 + synonymous_variant Silent SNP C C T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 77 57 93 0 ENST00000396328.1:c.687G>A p.Leu229= p.L229= ENST00000396328 NM_182758.3 229 ttG/ttA 0 +WWC3 UCSF GRCh37 X 10046914 10046914 + frameshift_variant,splice_region_variant Frame_Shift_Del DEL G G - NOVEL P04_Rec3 Untested WXS Illumina HiSeq 27 0 ENST00000380861.4:c.297+1del R99fs ENST00000380861 NM_015691.3 99 aGg/ag 0 +ZNF107 UCSF GRCh37 7 64167377 64167377 + missense_variant Missense_Mutation SNP C C G NOVEL P04_Rec3 Untested WXS Illumina HiSeq 90 58 128 0 ENST00000395391.1:c.695C>G p.Thr232Ser p.T232S ENST00000395391 232 aCt/aGt 0 +ZNF135 UCSF GRCh37 19 58579378 58579378 + missense_variant Missense_Mutation SNP T T C NOVEL P04_Rec3 Untested WXS Illumina HiSeq 148 27 145 1 ENST00000401053.4:c.1598T>C p.Leu533Pro p.L533P ENST00000401053 NM_001164529.1 533 cTc/cCc 0 +ZZEF1 UCSF GRCh37 17 3917753 3917753 + stop_gained Nonsense_Mutation SNP G G T NOVEL P04_Rec3 Untested WXS Illumina HiSeq 128 33 115 0 ENST00000381638.2:c.8202C>A p.Cys2734Ter p.C2734* ENST00000381638 NM_015113.3 2734 tgC/tgA 0 +AHCYL1 UCSF GRCh37 1 110561727 110561727 + missense_variant Missense_Mutation SNP A A C snp132_rs75754234 P05_Pri Untested WXS Illumina HiSeq 36 7 56 1 ENST00000369799.5:c.1372A>C p.Thr458Pro p.T458P ENST00000369799 NM_001242674.1 458 Aca/Cca 0 +ARID2 UCSF GRCh37 12 46244079 46244079 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Pri Untested WXS Illumina HiSeq 63 27 100 0 ENST00000334344.6:c.2173C>T p.Gln725Ter p.Q725* ENST00000334344 NM_152641.2 725 Cag/Tag 0 +ATAD5 UCSF GRCh37 17 29219740 29219740 + missense_variant Missense_Mutation SNP T T G snp132_rs74661926 P05_Pri Untested WXS Illumina HiSeq 61 15 101 0 ENST00000321990.4:c.4374T>G p.Cys1458Trp p.C1458W ENST00000321990 NM_024857.3 1458 tgT/tgG 0 +ATRX UCSF GRCh37 X 76890167 76890167 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Pri somatic WXS Sanger Illumina HiSeq 44 23 140 0 ENST00000373344.5:c.4727G>A p.Cys1576Tyr p.C1576Y ENST00000373344 NM_000489.3 1576 tGt/tAt 0 +ATRX UCSF GRCh37 X 76875979 76875979 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Pri Untested WXS Illumina HiSeq 52 9 54 0 ENST00000373344.5:c.5156A>G p.Asp1719Gly p.D1719G ENST00000373344 NM_000489.3 1719 gAt/gGt 0 +C6orf103 UCSF GRCh37 6 147012388 147012388 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 74 32 122 0 ENST00000397944.3:c.1448G>A p.Arg483His p.R483H ENST00000397944 NM_024694.3 483 cGt/cAt 0 +C7orf63 UCSF GRCh37 7 89906426 89906426 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Pri Untested WXS Illumina HiSeq 60 29 24 0 ENST00000389297.4:c.1024T>C p.Phe342Leu p.F342L ENST00000389297 NM_001039706.2 342 Ttt/Ctt 0 +CASP12 UCSF GRCh37 11 104761174 104761174 + synonymous_variant Silent SNP A A G NOVEL P05_Pri Untested WXS Illumina HiSeq 32 4 36 1 ENST00000422698.2:c.744T>C p.Gly248= p.G248= ENST00000422698 NM_001191016.1 248 ggT/ggC 0 +CCNC UCSF GRCh37 6 99993044 99993044 + synonymous_variant Silent SNP T T C NOVEL P05_Pri Untested WXS Illumina HiSeq 67 19 49 0 ENST00000520429.1:c.741A>G p.Arg247= p.R247= ENST00000520429 NM_005190.3 247 agA/agG 0 +CEACAM6 UCSF GRCh37 19 42260811 42260811 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P05_Pri Untested WXS Illumina HiSeq 38 0 ENST00000199764.6:c.369del p.Val124SerfsTer2 p.V124Sfs*2 ENST00000199764 NM_002483.4 123 cAa/ca 0 +CELA3B UCSF GRCh37 1 22310235 22310235 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.009,snp132_rs113497474 P05_Pri Untested WXS Illumina HiSeq 17 4 62 1 ENST00000337107.6:c.411C>T p.Asp137= p.D137= ENST00000337107 NM_007352.2 137 gaC/gaT 0 +CIT UCSF GRCh37 12 120148087 120148087 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Pri Untested WXS Illumina HiSeq 60 18 99 0 ENST00000392521.2:c.5040C>G p.Ile1680Met p.I1680M ENST00000392521 NM_001206999.1 1680 atC/atG 0 +CLK2 UCSF GRCh37 1 155238508 155238508 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Pri Untested WXS Illumina HiSeq 24 8 27 1 ENST00000361168.5:c.475C>A p.Gln159Lys p.Q159K ENST00000361168 159 Caa/Aaa 0 +CNNM2 UCSF GRCh37 10 104679671 104679671 + stop_gained Nonsense_Mutation SNP C C A NOVEL P05_Pri Untested WXS Illumina HiSeq 43 9 52 0 ENST00000369878.4:c.1434C>A p.Tyr478Ter p.Y478* ENST00000369878 NM_017649.4 478 taC/taA 0 +CSMD3 UCSF GRCh37 8 113326817 113326817 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Pri Untested WXS Illumina HiSeq 44 11 53 1 ENST00000297405.5:c.7390G>A p.Asp2464Asn p.D2464N ENST00000297405 NM_198123.1 2464 Gat/Aat 0 +FGF9 UCSF GRCh37 13 22246317 22246317 + missense_variant Missense_Mutation SNP A A C snp132_rs117849081 P05_Pri Untested WXS Illumina HiSeq 9 6 56 1 ENST00000382353.5:c.266A>C p.His89Pro p.H89P ENST00000382353 NM_002010.2 89 cAc/cCc 0 +GPC3 UCSF GRCh37 X 132888089 132888089 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Pri Untested WXS Illumina HiSeq 52 18 157 0 ENST00000394299.2:c.452A>T p.Asp151Val p.D151V ENST00000394299 NM_001164617.1 151 gAt/gTt 0 +HHLA1 UCSF GRCh37 8 133092007 133092007 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Pri Untested WXS Illumina HiSeq 12 11 15 1 ENST00000434736.2:c.991A>C p.Thr331Pro p.T331P ENST00000434736 331 Aca/Cca 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Pri Untested WXS Illumina HiSeq 40 24 75 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL1R1 UCSF GRCh37 2 102785059 102785059 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 44 18 57 0 ENST00000410023.1:c.657G>A p.Glu219= p.E219= ENST00000410023 219 gaG/gaA 0 +LRRC33 UCSF GRCh37 3 196388593 196388593 + stop_lost Nonstop_Mutation SNP A A G NOVEL P05_Pri Untested WXS Illumina HiSeq 16 3 35 0 ENST00000328557.4:c.2079A>G p.Ter693TrpextTer25 p.*693Wext*25 ENST00000328557 NM_198565.1 693 tgA/tgG 0 +LYVE1 UCSF GRCh37 11 10582206 10582206 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 50 16 85 0 ENST00000256178.3:c.539C>T p.Ala180Val p.A180V ENST00000256178 NM_006691.3 180 gCc/gTc 0 +MAGEC1 UCSF GRCh37 X 140994085 140994085 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.09062,1000g2011may_all_0.1531,snp132_rs176046 P05_Pri Untested WXS Illumina HiSeq 44 8 43 0 ENST00000285879.4:c.895C>G p.Pro299Ala p.P299A ENST00000285879 NM_005462.4 299 Ccc/Gcc 0 +MAP2 UCSF GRCh37 2 210569173 210569173 + intron_variant Intron SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 50 10 45 1 ENST00000360351.4:c.4585-1131G>A *1529* ENST00000360351 NM_002374.3 0 +NR1I3 UCSF GRCh37 1 161203098 161203098 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Pri Untested WXS Illumina HiSeq 27 7 72 0 ENST00000367980.2:c.269G>A p.Arg90Gln p.R90Q ENST00000367980 NM_001077481.2 90 cGg/cAg 0 +PCDH17 UCSF GRCh37 13 58298890 58298890 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Pri Untested WXS Illumina HiSeq 58 11 83 0 ENST00000377918.3:c.2942A>C p.Asn981Thr p.N981T ENST00000377918 NM_001040429.2 981 aAt/aCt 0 +PRDM5 UCSF GRCh37 4 121698436 121698436 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P05_Pri Untested WXS Illumina HiSeq 56 10 68 0 ENST00000264808.3:c.1444A>G p.Thr482Ala p.T482A ENST00000264808 NM_018699.2 482 Aca/Gca 0 +PRR14 UCSF GRCh37 16 30664057 30664057 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Pri Untested WXS Illumina HiSeq 11 5 44 0 ENST00000542965.2:c.208T>A p.Ser70Thr p.S70T ENST00000542965 70 Tca/Aca 0 +PZP UCSF GRCh37 12 9345272 9345272 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.00093 P05_Pri Untested WXS Illumina HiSeq 28 7 88 0 ENST00000261336.2:c.1318G>A p.Ala440Thr p.A440T ENST00000261336 NM_002864.2 440 Gct/Act 0 +SCN11A UCSF GRCh37 3 38888584 38888584 + synonymous_variant Silent SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 83 21 128 0 ENST00000302328.3:c.4977C>T p.Val1659= p.V1659= ENST00000302328 NM_014139.2 1659 gtC/gtT 0 +TSHZ3 UCSF GRCh37 19 31767507 31767507 + synonymous_variant Silent SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 43 18 58 0 ENST00000240587.4:c.3192C>T p.His1064= p.H1064= ENST00000240587 NM_020856.2 1064 caC/caT 0 +TSPEAR UCSF GRCh37 21 45945556 45945556 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 31 18 73 0 ENST00000323084.4:c.1316C>T p.Ala439Val p.A439V ENST00000323084 NM_001272037.1 439 gCg/gTg 0 +UNC13C UCSF GRCh37 15 54307971 54307971 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Pri Untested WXS Illumina HiSeq 19 12 39 0 ENST00000260323.11:c.2871A>C p.Glu957Asp p.E957D ENST00000260323 NM_001080534.1 957 gaA/gaC 0 +VIT UCSF GRCh37 2 37041424 37041424 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 23 4 71 0 ENST00000379242.3:c.2002G>A p.Glu668Lys p.E668K ENST00000379242 NM_053276.3 668 Gag/Aag 0 +ZFAND2B UCSF GRCh37 2 220072104 220072104 + synonymous_variant Silent SNP G G A NOVEL P05_Pri Untested WXS Illumina HiSeq 12 5 47 0 ENST00000289528.5:c.111G>A p.Val37= p.V37= ENST00000289528 NM_001270999.1 37 gtG/gtA 0 +ZNF485 UCSF GRCh37 10 44104090 44104090 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Pri Untested WXS Illumina HiSeq 28 12 58 2 ENST00000361807.3:c.53T>G p.Val18Gly p.V18G ENST00000361807 NM_145312.3 18 gTg/gGg 0 +A2M UCSF GRCh37 12 9264996 9264996 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 73 139 0 ENST00000318602.7:c.407C>T p.Ser136Leu p.S136L ENST00000318602 NM_000014.4 136 tCa/tTa 0 +A4GNT UCSF GRCh37 3 137849742 137849742 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 40 87 0 ENST00000236709.3:c.357G>A p.Leu119= p.L119= ENST00000236709 NM_016161.2 119 ttG/ttA 0 +AAMP UCSF GRCh37 2 219131667 219131667 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 63 68 0 ENST00000248450.4:c.437C>T p.Ser146Phe p.S146F ENST00000248450 146 tCc/tTc 0 +AANAT UCSF GRCh37 17 74464874 74464874 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 6 11 0 ENST00000250615.3:c.181C>T p.Leu61= p.L61= ENST00000250615 NM_001166579.1 61 Ctg/Ttg 0 +AARS UCSF GRCh37 16 70298924 70298924 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 25 34 0 ENST00000261772.8:c.1429G>A p.Gly477Ser p.G477S ENST00000261772 NM_001605.2 477 Ggt/Agt 0 +AASDH UCSF GRCh37 4 57204659 57204659 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 37 58 0 ENST00000205214.6:c.3206C>T p.Ser1069Phe p.S1069F ENST00000205214 NM_181806.2 1069 tCt/tTt 0 +AASS UCSF GRCh37 7 121773620 121773620 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 32 93 0 ENST00000393376.1:c.161G>A p.Gly54Glu p.G54E ENST00000393376 54 gGa/gAa 0 +ABCA1 UCSF GRCh37 9 107547804 107547804 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 50 72 0 ENST00000374736.3:c.6518G>A p.Arg2173Gln p.R2173Q ENST00000374736 NM_005502.3 2173 cGg/cAg 0 +ABCA12 UCSF GRCh37 2 215891637 215891637 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 163 108 103 0 ENST00000272895.7:c.1087G>A p.Asp363Asn p.D363N ENST00000272895 NM_173076.2 363 Gat/Aat 0 +ABCA13 UCSF GRCh37 7 48414007 48414007 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 123 48 102 0 ENST00000435803.1:c.11197G>A p.Glu3733Lys p.E3733K ENST00000435803 NM_152701.3 3733 Gag/Aag 0 +ABCA4 UCSF GRCh37 1 94546147 94546147 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 49 95 0 ENST00000370225.3:c.986G>A p.Gly329Glu p.G329E ENST00000370225 NM_000350.2 329 gGa/gAa 0 +ABCA9 UCSF GRCh37 17 66982360 66982360 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 29 61 0 ENST00000340001.4:c.4153G>A p.Val1385Met p.V1385M ENST00000340001 NM_080283.3 1385 Gtg/Atg 0 +ABCB4 UCSF GRCh37 7 87051535 87051535 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 7 44 0 ENST00000265723.4:c.2218G>A p.Gly740Arg p.G740R ENST00000265723 NM_000443.3 740 Gga/Aga 0 +ABCC12 UCSF GRCh37 16 48138152 48138152 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 206 78 126 0 ENST00000311303.3:c.2801T>G p.Phe934Cys p.F934C ENST00000311303 NM_033226.2 934 tTt/tGt 0 +ABCF3 UCSF GRCh37 3 183906749 183906749 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 33 56 0 ENST00000429586.2:c.950C>T p.Thr317Ile p.T317I ENST00000429586 NM_018358.2 317 aCc/aTc 0 +ABHD12 UCSF GRCh37 20 25304020 25304020 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 80 38 74 0 ENST00000376542.3:c.363T>C p.Gly121= p.G121= ENST00000376542 NM_015600.4 121 ggT/ggC 0 +ABHD16B UCSF GRCh37 20 62493648 62493648 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 15 9 0 ENST00000369916.3:c.755C>T p.Thr252Met p.T252M ENST00000369916 NM_080622.3 252 aCg/aTg 0 +ABHD6 UCSF GRCh37 3 58242354 58242354 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 132 36 66 0 ENST00000478253.1:c.41G>A p.Gly14Asp p.G14D ENST00000478253 14 gGc/gAc 0 +ABI3 UCSF GRCh37 17 47297537 47297537 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 5 12 0 ENST00000225941.1:c.651C>T p.Ala217= p.A217= ENST00000225941 NM_016428.2 217 gcC/gcT 0 +ACACB UCSF GRCh37 12 109679082 109679082 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 163 66 79 0 ENST00000338432.7:c.5018G>A p.Gly1673Glu p.G1673E ENST00000338432 1673 gGa/gAa 0 +ACACB UCSF GRCh37 12 109650679 109650679 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 128 37 84 0 ENST00000338432.7:c.3288G>A p.Gln1096= p.Q1096= ENST00000338432 1096 caG/caA 0 +ACAD10 UCSF GRCh37 12 112167638 112167638 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 14 49 0 ENST00000455480.2:c.1365C>T p.Thr455= p.T455= ENST00000455480 NM_001136538.1 455 acC/acT 0 +ACADVL UCSF GRCh37 17 7125571 7125571 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 41 86 0 ENST00000543245.2:c.897G>A p.Lys299= p.K299= ENST00000543245 NM_001270447.1 299 aaG/aaA 0 +ACAN UCSF GRCh37 15 89390536 89390536 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 12 10 0 ENST00000439576.2:c.1492C>T p.Gln498Ter p.Q498* ENST00000439576 NM_013227.3 498 Cag/Tag 0 +ACAN UCSF GRCh37 15 89395258 89395258 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 30 53 0 ENST00000439576.2:c.2260C>T p.Leu754= p.L754= ENST00000439576 NM_013227.3 754 Ctg/Ttg 0 +ACAN UCSF GRCh37 15 89416168 89416168 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 28 54 0 ENST00000439576.2:c.7245C>T p.Asp2415= p.D2415= ENST00000439576 NM_013227.3 2415 gaC/gaT 0 +ACCN3 UCSF GRCh37 7 150747871 150747871 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 24 26 0 ENST00000297512.8:c.840C>T p.Gly280= p.G280= ENST00000297512 280 ggC/ggT 0 +ACCN4 UCSF GRCh37 2 220379918 220379918 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 49 24 0 ENST00000347842.3:c.853C>T p.Pro285Ser p.P285S ENST00000347842 NM_182847.2 285 Cca/Tca 0 +ACE2 UCSF GRCh37 X 15599355 15599355 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 39 74 146 0 ENST00000427411.1:c.1059G>A p.Lys353= p.K353= ENST00000427411 NM_021804.2 353 aaG/aaA 0 +ACO2 UCSF GRCh37 22 41903918 41903918 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 17 32 22 0 ENST00000216254.4:c.297G>A p.Gln99= p.Q99= ENST00000216254 NM_001098.2 99 caG/caA 0 +ACOT12 UCSF GRCh37 5 80626242 80626242 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 21 71 0 ENST00000307624.3:c.1639C>T p.Pro547Ser p.P547S ENST00000307624 NM_130767.2 547 Cct/Tct 0 +ACP6 UCSF GRCh37 1 147126370 147126370 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 37 76 0 ENST00000369238.6:c.719G>A p.Gly240Asp p.G240D ENST00000369238 NM_016361.4 240 gGc/gAc 0 +ACSL6 UCSF GRCh37 5 131323748 131323748 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 59 120 0 ENST00000379264.2:c.824C>T p.Ala275Val p.A275V ENST00000379264 NM_001009185.2 275 gCc/gTc 0 +ACTN4 UCSF GRCh37 19 39218666 39218666 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 22 10 0 ENST00000252699.2:c.2418G>A p.Gln806= p.Q806= ENST00000252699 NM_004924.4 806 caG/caA 0 +ACTR1B UCSF GRCh37 2 98275454 98275454 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 64 71 0 ENST00000289228.5:c.328C>T p.Leu110Phe p.L110F ENST00000289228 NM_005735.3 110 Ctc/Ttc 0 +ACTR3B UCSF GRCh37 7 152497666 152497666 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 266 87 208 0 ENST00000256001.8:c.151G>A p.Val51Met p.V51M ENST00000256001 NM_020445.5 51 Gtg/Atg 0 +ACVR2A UCSF GRCh37 2 148657339 148657339 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 177 104 251 0 ENST00000241416.7:c.400C>T p.Pro134Ser p.P134S ENST00000241416 NM_001616.4 134 Cca/Tca 0 +ACVR2B UCSF GRCh37 3 38523998 38523998 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 7 19 0 ENST00000352511.4:c.1291G>A p.Val431Met p.V431M ENST00000352511 NM_001106.3 431 Gtg/Atg 0 +ADAM22 UCSF GRCh37 7 87762229 87762229 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 19 46 0 ENST00000265727.7:c.1040G>A p.Gly347Glu p.G347E ENST00000265727 347 gGg/gAg 0 +ADAM23 UCSF GRCh37 2 207426926 207426926 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 199 124 201 0 ENST00000264377.3:c.1255-1G>A p.X419_splice ENST00000264377 NM_003812.3 0 +ADAMTS12 UCSF GRCh37 5 33561169 33561169 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 60 84 0 ENST00000504830.1:c.4088G>A p.Arg1363His p.R1363H ENST00000504830 NM_030955.2 1363 cGt/cAt 0 +ADAMTS14 UCSF GRCh37 10 72520286 72520286 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 38 41 0 ENST00000373208.1:c.3358C>T p.Pro1120Ser p.P1120S ENST00000373208 NM_139155.2 1120 Cct/Tct 0 +ADAMTS9 UCSF GRCh37 3 64666961 64666961 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 20 37 0 ENST00000498707.1:c.595G>A p.Glu199Lys p.E199K ENST00000498707 NM_182920.1 199 Gaa/Aaa 0 +ADAMTSL3 UCSF GRCh37 15 84611718 84611718 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 33 32 0 ENST00000286744.5:c.2374G>A p.Asp792Asn p.D792N ENST00000286744 NM_207517.2 792 Gat/Aat 0 +ADCY10 UCSF GRCh37 1 167815414 167815414 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 61 109 0 ENST00000367851.4:c.2525C>T p.Thr842Ile p.T842I ENST00000367851 NM_018417.4 842 aCt/aTt 0 +ADCY2 UCSF GRCh37 5 7717290 7717290 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 32 47 0 ENST00000338316.4:c.1643G>A p.Arg548Lys p.R548K ENST00000338316 NM_020546.2 548 aGa/aAa 0 +ADCY7 UCSF GRCh37 16 50348926 50348926 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 139 136 104 0 ENST00000394697.2:c.2973C>T p.Gly991= p.G991= ENST00000394697 991 ggC/ggT 0 +ADD2 UCSF GRCh37 2 70904949 70904949 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 47 58 0 ENST00000264436.4:c.1444C>T p.Pro482Ser p.P482S ENST00000264436 NM_001617.3 482 Cca/Tca 0 +ADORA1 UCSF GRCh37 1 203134985 203134985 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 40 53 0 ENST00000367236.4:c.938C>T p.Pro313Leu p.P313L ENST00000367236 NM_001048230.1 313 cCt/cTt 0 +ADRA2B UCSF GRCh37 2 96781752 96781752 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 21 8 0 ENST00000409345.3:c.137C>T p.Pro46Leu p.P46L ENST00000409345 NM_000682.5 46 cCt/cTt 0 +AEBP1 UCSF GRCh37 7 44149871 44149871 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 22 35 0 ENST00000223357.3:c.1326G>A p.Gln442= p.Q442= ENST00000223357 NM_001129.4 442 caG/caA 0 +AFF3 UCSF GRCh37 2 100210059 100210059 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 88 43 0 ENST00000356421.2:c.2139C>T p.Tyr713= p.Y713= ENST00000356421 NM_001025108.1 713 taC/taT 0 +AGAP11 UCSF GRCh37 10 88768200 88768200 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 115 270 1 ENST00000433214.2:n.1395G>A *465* ENST00000433214 0 +AGBL2 UCSF GRCh37 11 47707481 47707481 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 53 139 0 ENST00000525123.1:c.1752C>T p.Val584= p.V584= ENST00000525123 NM_024783.3 584 gtC/gtT 0 +AGK UCSF GRCh37 7 141352686 141352686 + splice_region_variant,intron_variant,non_coding_transcript_variant Splice_Region SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 171 57 74 0 ENST00000467537.1:n.268-3T>G p.X90_splice ENST00000467537 0 +AGL UCSF GRCh37 1 100316681 100316681 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 52 71 0 ENST00000294724.4:c.82+1G>A p.X28_splice ENST00000294724 NM_000028.2 0 +AGPAT2 UCSF GRCh37 9 139571054 139571054 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 30 20 0 ENST00000371696.2:c.571C>T p.Leu191= p.L191= ENST00000371696 NM_006412.3 191 Ctg/Ttg 0 +AHRR UCSF GRCh37 5 434260 434260 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 34 24 0 ENST00000316418.5:c.1471C>T p.Arg491Trp p.R491W ENST00000316418 NM_020731.4 491 Cgg/Tgg 0 +AHRR UCSF GRCh37 5 427752 427752 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 51 33 0 ENST00000316418.5:c.721G>A p.Ala241Thr p.A241T ENST00000316418 NM_020731.4 241 Gcc/Acc 0 +AHSA1 UCSF GRCh37 14 77929093 77929093 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 29 66 0 ENST00000216479.3:c.463C>T p.Leu155Phe p.L155F ENST00000216479 NM_012111.2 155 Ctc/Ttc 0 +AIFM1 UCSF GRCh37 X 129281803 129281803 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 76 155 0 ENST00000287295.3:c.398C>T p.Pro133Leu p.P133L ENST00000287295 NM_004208.3 133 cCt/cTt 0 +AIPL1 UCSF GRCh37 17 6329947 6329947 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 23 18 0 ENST00000381129.3:c.772C>T p.Arg258Trp p.R258W ENST00000381129 NM_014336.3 258 Cgg/Tgg 0 +AIPL1 UCSF GRCh37 17 6329972 6329972 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 32 21 0 ENST00000381129.3:c.747G>A p.Val249= p.V249= ENST00000381129 NM_014336.3 249 gtG/gtA 0 +AK7 UCSF GRCh37 14 96953269 96953269 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 14 42 0 ENST00000267584.4:c.2009G>A p.Arg670Lys p.R670K ENST00000267584 NM_152327.3 670 aGa/aAa 0 +AKAP8 UCSF GRCh37 19 15483797 15483797 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 19 11 0 ENST00000269701.2:c.726G>A p.Arg242= p.R242= ENST00000269701 NM_005858.3 242 cgG/cgA 0 +AKD1 UCSF GRCh37 6 109835578 109835578 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 35 94 0 ENST00000424296.2:c.4128C>T p.Ile1376= p.I1376= ENST00000424296 NM_001145128.2 1376 atC/atT 0 +AKNA UCSF GRCh37 9 117119143 117119143 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 48 54 0 ENST00000307564.4:c.2846G>A p.Ser949Asn p.S949N ENST00000307564 NM_030767.4 949 aGc/aAc 0 +AKNAD1 UCSF GRCh37 1 109395078 109395078 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 80 88 0 ENST00000370001.3:c.209C>T p.Thr70Ile p.T70I ENST00000370001 NM_152763.4 70 aCc/aTc 0 +AKNAD1 UCSF GRCh37 1 109385874 109385874 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 44 54 0 ENST00000370001.3:c.1261C>T p.Gln421Ter p.Q421* ENST00000370001 NM_152763.4 421 Cag/Tag 0 +ALCAM UCSF GRCh37 3 105260490 105260490 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 17 60 0 ENST00000306107.5:c.872G>A p.Gly291Glu p.G291E ENST00000306107 NM_001627.3 291 gGa/gAa 0 +ALDH4A1 UCSF GRCh37 1 19202840 19202840 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 31 31 0 ENST00000375341.3:c.1307G>A p.Ser436Asn p.S436N ENST00000375341 NM_003748.3 436 aGc/aAc 0 +ALDH4A1 UCSF GRCh37 1 19204034 19204034 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 19 9 0 ENST00000375341.3:c.1013G>A p.Arg338His p.R338H ENST00000375341 NM_003748.3 338 cGc/cAc 0 +ALG11 UCSF GRCh37 13 52598626 52598626 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 70 93 0 ENST00000521508.1:c.760G>A p.Val254Ile p.V254I ENST00000521508 NM_001004127.2 254 Gtc/Atc 0 +ALKBH3 UCSF GRCh37 11 43904246 43904246 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 8 26 36 0 ENST00000302708.4:c.44C>T p.Ala15Val p.A15V ENST00000302708 NM_139178.3 15 gCt/gTt 0 +ALMS1 UCSF GRCh37 2 73675096 73675096 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 20 38 66 0 ENST00000264448.6:c.1439C>T p.Thr480Ile p.T480I ENST00000264448 NM_015120.4 480 aCt/aTt 0 +ALOX15B UCSF GRCh37 17 7948887 7948887 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 25 35 0 ENST00000380183.4:c.1083C>T p.Arg361= p.R361= ENST00000380183 NM_001141.2 361 cgC/cgT 0 +ALOXE3 UCSF GRCh37 17 8020099 8020099 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 20 42 0 ENST00000318227.3:c.743G>A p.Gly248Glu p.G248E ENST00000318227 NM_001165960.1 248 gGa/gAa 0 +ALOXE3 UCSF GRCh37 17 8014809 8014809 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 27 71 0 ENST00000318227.3:c.1221G>A p.Gly407= p.G407= ENST00000318227 NM_001165960.1 407 ggG/ggA 0 +ALPPL2 UCSF GRCh37 2 233274294 233274294 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 9 12 12 0 ENST00000295453.3:c.1311G>A p.Glu437= p.E437= ENST00000295453 NM_031313.2 437 gaG/gaA 0 +ALS2CR11 UCSF GRCh37 2 202359129 202359129 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 167 92 170 0 ENST00000439140.1:c.1935G>A p.Arg645= p.R645= ENST00000439140 NM_001168221.1 645 agG/agA 0 +ALS2CR11 UCSF GRCh37 2 202359204 202359204 + synonymous_variant Silent SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 142 69 145 0 ENST00000439140.1:c.1860T>G p.Gly620= p.G620= ENST00000439140 NM_001168221.1 620 ggT/ggG 0 +AMOTL2 UCSF GRCh37 3 134089737 134089737 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 18 23 0 ENST00000249883.5:c.539C>T p.Ser180Phe p.S180F ENST00000249883 NM_016201.3 180 tCc/tTc 0 +AMY2B UCSF GRCh37 1 104115845 104115845 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 217 135 218 0 ENST00000361355.4:c.476G>A p.Gly159Glu p.G159E ENST00000361355 NM_020978.4 159 gGa/gAa 0 +ANAPC5 UCSF GRCh37 12 121746438 121746438 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 108 40 109 0 ENST00000261819.3:c.2113G>A p.Asp705Asn p.D705N ENST00000261819 NM_016237.4 705 Gac/Aac 0 +ANK2 UCSF GRCh37 4 114294449 114294449 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 38 110 0 ENST00000357077.4:c.11703G>A p.Arg3901= p.R3901= ENST00000357077 NM_001148.4 3901 agG/agA 0 +ANKFY1 UCSF GRCh37 17 4074130 4074130 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 22 34 0 ENST00000570535.1:c.3291G>A p.Gly1097= p.G1097= ENST00000570535 NM_001257999.1 1097 ggG/ggA 0 +ANKHD1 UCSF GRCh37 5 139908515 139908515 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 73 127 0 ENST00000297183.6:c.5984C>T p.Thr1995Ile p.T1995I ENST00000297183 NM_020690.5 1995 aCt/aTt 0 +ANKLE2 UCSF GRCh37 12 133324426 133324426 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 47 59 0 ENST00000357997.5:c.1222G>A p.Asp408Asn p.D408N ENST00000357997 NM_015114.1 408 Gac/Aac 0 +ANKRD1 UCSF GRCh37 10 92680047 92680047 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 82 157 0 ENST00000371697.3:c.86G>A p.Arg29Lys p.R29K ENST00000371697 NM_014391.2 29 aGa/aAa 0 +ANKRD11 UCSF GRCh37 16 89351166 89351166 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 108 42 59 0 ENST00000301030.4:c.1784G>A p.Arg595Lys p.R595K ENST00000301030 NM_001256183.1 595 aGg/aAg 0 +ANKRD11 UCSF GRCh37 16 89347886 89347886 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 255 96 39 0 ENST00000301030.4:c.5064C>T p.Val1688= p.V1688= ENST00000301030 NM_001256183.1 1688 gtC/gtT 0 +ANKRD11 UCSF GRCh37 16 89371699 89371699 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 112 29 20 0 ENST00000301030.4:c.141C>T p.Gly47= p.G47= ENST00000301030 NM_001256183.1 47 ggC/ggT 0 +ANKRD11 UCSF GRCh37 16 89341222 89341222 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 46 40 0 ENST00000301030.4:c.7713G>A p.Gln2571= p.Q2571= ENST00000301030 NM_001256183.1 2571 caG/caA 0 +ANKRD13A UCSF GRCh37 12 110456212 110456212 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 40 51 0 ENST00000261739.4:c.463C>T p.Leu155= p.L155= ENST00000261739 NM_033121.1 155 Ctg/Ttg 0 +ANKRD24 UCSF GRCh37 19 4216973 4216973 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 34 29 0 ENST00000600132.1:c.1816G>A p.Val606Ile p.V606I ENST00000600132 NM_133475.1 606 Gtc/Atc 0 +ANKRD46 UCSF GRCh37 8 101540115 101540115 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 33 75 0 ENST00000520552.1:c.428C>T p.Thr143Ile p.T143I ENST00000520552 NM_001270379.1 143 aCc/aTc 0 +ANKRD6 UCSF GRCh37 6 90333154 90333154 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 12 27 0 ENST00000522441.1:c.923C>T p.Pro308Leu p.P308L ENST00000522441 NM_001242811.1 308 cCc/cTc 0 +ANLN UCSF GRCh37 7 36455449 36455449 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 195 70 100 0 ENST00000265748.2:c.1478C>T p.Thr493Ile p.T493I ENST00000265748 NM_018685.2 493 aCc/aTc 0 +ANO10 UCSF GRCh37 3 43647213 43647213 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P05_Rec Untested WXS Illumina HiSeq 10 0 ENST00000292246.3:c.132delA p.Asp45MetfsTer12 p.D45Mfs*12 ENST00000292246 NM_018075.3 44 aaA/aa 0 +ANO2 UCSF GRCh37 12 5963241 5963241 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 143 76 141 0 ENST00000327087.8:c.589G>A p.Glu197Lys p.E197K ENST00000327087 NM_001278596.1 197 Gaa/Aaa 0 +AOC3 UCSF GRCh37 17 41006513 41006513 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 22 30 0 ENST00000308423.2:c.1649C>T p.Ala550Val p.A550V ENST00000308423 NM_003734.3 550 gCt/gTt 0 +AP1AR UCSF GRCh37 4 113186173 113186173 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 108 55 94 0 ENST00000274000.5:c.390G>A p.Arg130= p.R130= ENST00000274000 NM_018569.4 130 agG/agA 0 +AP1M1 UCSF GRCh37 19 16314331 16314331 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 32 40 0 ENST00000444449.2:c.104C>T p.Pro35Leu p.P35L ENST00000444449 NM_001130524.1 35 cCc/cTc 0 +APCDD1 UCSF GRCh37 18 10485656 10485656 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 32 45 0 ENST00000355285.5:c.972C>T p.Gly324= p.G324= ENST00000355285 NM_153000.4 324 ggC/ggT 0 +APCDD1L UCSF GRCh37 20 57042262 57042262 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 15 12 0 ENST00000371149.3:c.641G>A p.Arg214Gln p.R214Q ENST00000371149 NM_153360.1 214 cGg/cAg 0 +APEX2 UCSF GRCh37 X 55033194 55033194 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 51 20 30 0 ENST00000374987.3:c.883C>T p.Leu295= p.L295= ENST00000374987 NM_014481.3 295 Ctg/Ttg 0 +APOA2 UCSF GRCh37 1 161192746 161192746 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 32 63 0 ENST00000367990.3:c.147G>A p.Met49Ile p.M49I ENST00000367990 NM_001643.1 49 atG/atA 0 +APOB UCSF GRCh37 2 21232717 21232717 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 58 119 0 ENST00000233242.1:c.7023C>T p.Val2341= p.V2341= ENST00000233242 NM_000384.2 2341 gtC/gtT 0 +APOC3 UCSF GRCh37 11 116701560 116701560 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 28 11 14 0 ENST00000227667.3:c.127G>A p.Ala43Thr p.A43T ENST00000227667 NM_000040.1 43 Gcc/Acc 0 +APOF UCSF GRCh37 12 56755627 56755627 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 41 71 0 ENST00000398189.3:c.363G>A p.Gln121= p.Q121= ENST00000398189 NM_001638.2 121 caG/caA 0 +APOL2 UCSF GRCh37 22 36624040 36624040 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 22 65 0 ENST00000249066.6:c.424G>A p.Glu142Lys p.E142K ENST00000249066 NM_145637.1 142 Gaa/Aaa 0 +APOL5 UCSF GRCh37 22 36123218 36123218 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 30 41 0 ENST00000249044.2:c.1103G>A p.Gly368Glu p.G368E ENST00000249044 NM_030642.1 368 gGa/gAa 0 +APTX UCSF GRCh37 9 32987663 32987663 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 118 59 128 0 ENST00000379813.3:c.362G>A p.Ser121Asn p.S121N ENST00000379813 121 aGt/aAt 0 +AQP12B UCSF GRCh37 2 241622083 241622083 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 12 48 23 0 ENST00000407834.3:c.172G>A p.Val58Ile p.V58I ENST00000407834 NM_001102467.1 58 Gtc/Atc 0 +AR UCSF GRCh37 X 66863097 66863097 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 34 65 0 ENST00000374690.3:c.1617-1G>A p.X539_splice ENST00000374690 NM_000044.3 0 +ARAP1 UCSF GRCh37 11 72415292 72415292 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 37 9 0 ENST00000393609.3:c.1897C>T p.Pro633Ser p.P633S ENST00000393609 NM_001040118.2 633 Ccc/Tcc 0 +ARAP3 UCSF GRCh37 5 141033718 141033718 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 7 17 38 0 ENST00000239440.4:c.4434G>A p.Arg1478= p.R1478= ENST00000239440 NM_022481.5 1478 cgG/cgA 0 +ARC UCSF GRCh37 8 143694837 143694837 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 38 37 0 ENST00000356613.2:c.796G>A p.Glu266Lys p.E266K ENST00000356613 NM_015193.4 266 Gag/Aag 0 +ARFGEF1 UCSF GRCh37 8 68179357 68179357 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 42 77 0 ENST00000262215.3:c.1781G>A p.Gly594Asp p.G594D ENST00000262215 NM_006421.4 594 gGc/gAc 0 +ARGLU1 UCSF GRCh37 13 107211856 107211856 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 28 168 0 ENST00000400198.3:c.497G>A p.Arg166His p.R166H ENST00000400198 NM_018011.3 166 cGc/cAc 0 +ARHGAP20 UCSF GRCh37 11 110450171 110450171 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 60 95 0 ENST00000260283.4:c.3499G>A p.Glu1167Lys p.E1167K ENST00000260283 NM_020809.3 1167 Gag/Aag 0 +ARHGAP20 UCSF GRCh37 11 110453055 110453055 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 142 75 125 0 ENST00000260283.4:c.1710G>A p.Glu570= p.E570= ENST00000260283 NM_020809.3 570 gaG/gaA 0 +ARHGEF10L UCSF GRCh37 1 17948377 17948377 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 59 48 30 0 ENST00000361221.3:c.961C>G p.Leu321Val p.L321V ENST00000361221 NM_018125.3 321 Ctg/Gtg 0 +ARHGEF15 UCSF GRCh37 17 8219385 8219385 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 14 14 0 ENST00000361926.3:c.1623C>T p.Leu541= p.L541= ENST00000361926 NM_173728.3 541 ctC/ctT 0 +ARHGEF18 UCSF GRCh37 19 7535023 7535023 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 55 46 0 ENST00000359920.6:c.3361C>T p.Pro1121Ser p.P1121S ENST00000359920 NM_001130955.1 1121 Ccc/Tcc 0 +ARHGEF2 UCSF GRCh37 1 155935434 155935434 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 46 49 0 ENST00000361247.4:c.458C>T p.Thr153Ile p.T153I ENST00000361247 NM_001162384.1 153 aCc/aTc 0 +ARHGEF25 UCSF GRCh37 12 58008323 58008323 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 32 50 0 ENST00000333972.7:c.868G>A p.Val290Met p.V290M ENST00000333972 NM_001111270.2 290 Gtg/Atg 0 +ARHGEF40 UCSF GRCh37 14 21542414 21542414 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 37 47 0 ENST00000298694.4:c.525G>A p.Arg175= p.R175= ENST00000298694 NM_001278529.1 175 cgG/cgA 0 +ARID1A UCSF GRCh37 1 27092831 27092831 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 42 70 0 ENST00000324856.7:c.2852G>A p.Gly951Asp p.G951D ENST00000324856 NM_006015.4 951 gGt/gAt 0 +ARID1B UCSF GRCh37 6 157522031 157522031 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 47 27 0 ENST00000346085.5:c.4303C>T p.Pro1435Ser p.P1435S ENST00000346085 NM_020732.3 1435 Ccg/Tcg 0 +ARL4A UCSF GRCh37 7 12728105 12728105 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 67 154 0 ENST00000396663.1:c.226G>A p.Val76Ile p.V76I ENST00000396663 NM_005738.4 76 Gta/Ata 0 +ARL6 UCSF GRCh37 3 97499033 97499033 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 49 44 0 ENST00000463745.1:c.154G>A p.Gly52Arg p.G52R ENST00000463745 NM_001278293.1 52 Gga/Aga 0 +ARMC4 UCSF GRCh37 10 28225673 28225673 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 112 61 152 1 ENST00000305242.5:c.2234G>A p.Ser745Asn p.S745N ENST00000305242 NM_018076.2 745 aGc/aAc 0 +ARMCX5 UCSF GRCh37 X 101857642 101857642 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 82 136 0 ENST00000604957.1:c.573G>A p.Glu191= p.E191= ENST00000604957 NM_001168478.1 191 gaG/gaA 0 +ARNT UCSF GRCh37 1 150814899 150814899 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 25 83 0 ENST00000358595.5:c.272+1G>A p.X91_splice ENST00000358595 NM_178427.2 0 +ARPP21 UCSF GRCh37 3 35748507 35748507 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 21 65 0 ENST00000458225.1:c.728G>A p.Gly243Asp p.G243D ENST00000458225 243 gGt/gAt 0 +ARRDC5 UCSF GRCh37 19 4902759 4902759 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 60 124 0 ENST00000381781.2:c.121G>A p.Val41Met p.V41M ENST00000381781 NM_001080523.1 41 Gtg/Atg 0 +ARRDC5 UCSF GRCh37 19 4891544 4891544 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 68 77 0 ENST00000381781.2:c.543C>T p.Asn181= p.N181= ENST00000381781 NM_001080523.1 181 aaC/aaT 0 +ARSH UCSF GRCh37 X 2942141 2942141 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 11 22 27 0 ENST00000381130.2:c.981C>T p.His327= p.H327= ENST00000381130 NM_001011719.1 327 caC/caT 0 +ASAH1 UCSF GRCh37 8 17915063 17915063 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 14 23 0 ENST00000381733.4:c.1216G>A p.Asp406Asn p.D406N ENST00000381733 NM_004315.4 406 Gac/Aac 0 +ASB6 UCSF GRCh37 9 132400594 132400594 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 37 30 0 ENST00000277458.4:c.741G>A p.Leu247= p.L247= ENST00000277458 NM_017873.3 247 ctG/ctA 0 +ASCC2 UCSF GRCh37 22 30210654 30210654 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 21 33 0 ENST00000397771.2:c.712C>T p.Pro238Ser p.P238S ENST00000397771 238 Cct/Tct 0 +ASPH UCSF GRCh37 8 62430118 62430118 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 39 62 0 ENST00000379454.4:c.2095G>A p.Gly699Ser p.G699S ENST00000379454 NM_004318.3 699 Ggc/Agc 0 +ASPHD2 UCSF GRCh37 22 26830109 26830109 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 34 39 0 ENST00000215906.5:c.528G>A p.Thr176= p.T176= ENST00000215906 NM_020437.4 176 acG/acA 0 +ASPM UCSF GRCh37 1 197072633 197072633 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 64 117 0 ENST00000367409.4:c.5748G>A p.Gln1916= p.Q1916= ENST00000367409 NM_018136.4 1916 caG/caA 0 +ASXL1 UCSF GRCh37 20 31021696 31021696 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 85 86 0 ENST00000375687.4:c.1695G>A p.Glu565= p.E565= ENST00000375687 NM_015338.5 565 gaG/gaA 0 +ATF7 UCSF GRCh37 12 53931335 53931335 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 94 60 159 0 ENST00000420353.2:c.266C>T p.Ala89Val p.A89V ENST00000420353 NM_006856.2 89 gCt/gTt 0 +ATG13 UCSF GRCh37 11 46690417 46690417 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 28 57 0 ENST00000528494.1:c.1403G>A p.Gly468Asp p.G468D ENST00000528494 NM_001205119.1 468 gGc/gAc 0 +ATG2A UCSF GRCh37 11 64677367 64677367 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 29 10 0 ENST00000377264.3:c.1893G>A p.Gln631= p.Q631= ENST00000377264 NM_015104.2 631 caG/caA 0 +ATM UCSF GRCh37 11 108155178 108155178 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 57 33 0 ENST00000278616.4:c.3971G>A p.Ser1324Asn p.S1324N ENST00000278616 NM_000051.3 1324 aGt/aAt 0 +ATN1 UCSF GRCh37 12 7045938 7045939 + protein_altering_variant In_Frame_Ins INS - - AGCAGCAGC NOVEL P05_Rec Untested WXS Illumina HiSeq 7 0 ENST00000356654.4:c.1508_1509insAGCAGCAGC p.His503delinsGlnAlaAlaAla p.H503delinsQAAA ENST00000356654 NM_001007026.1 503 cat/caAGCAGCAGCt 0 +ATP11A UCSF GRCh37 13 113512565 113512565 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 44 55 0 ENST00000487903.1:c.2628C>T p.Tyr876= p.Y876= ENST00000487903 876 taC/taT 0 +ATP13A4 UCSF GRCh37 3 193183851 193183851 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 145 69 145 0 ENST00000342695.4:c.1235G>A p.Gly412Glu p.G412E ENST00000342695 NM_032279.2 412 gGg/gAg 0 +ATP13A4 UCSF GRCh37 3 193166011 193166011 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 30 80 0 ENST00000342695.4:c.2136G>A p.Arg712= p.R712= ENST00000342695 NM_032279.2 712 agG/agA 0 +ATP1A2 UCSF GRCh37 1 160094966 160094966 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 30 43 0 ENST00000361216.3:c.671C>T p.Thr224Ile p.T224I ENST00000361216 NM_000702.3 224 aCc/aTc 0 +ATP1B4 UCSF GRCh37 X 119500574 119500574 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 49 63 0 ENST00000218008.3:c.258G>A p.Leu86= p.L86= ENST00000218008 NM_001142447.2 86 ttG/ttA 0 +ATP2A1 UCSF GRCh37 16 28912191 28912191 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 39 46 0 ENST00000357084.3:c.2054C>T p.Ser685Phe p.S685F ENST00000357084 NM_173201.3 685 tCc/tTc 0 +ATP2B1 UCSF GRCh37 12 89984838 89984838 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 66 117 0 ENST00000428670.3:c.3586C>T p.Leu1196Phe p.L1196F ENST00000428670 1196 Ctt/Ttt 0 +ATP2B2 UCSF GRCh37 3 10382388 10382388 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 37 37 0 ENST00000360273.2:c.2918G>A p.Gly973Asp p.G973D ENST00000360273 NM_001001331.2 973 gGc/gAc 0 +ATP2B4 UCSF GRCh37 1 203668793 203668793 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 136 80 118 0 ENST00000357681.5:c.597C>T p.Ile199= p.I199= ENST00000357681 NM_001684.4 199 atC/atT 0 +ATP5J2-PTCD1 UCSF GRCh37 7 99032460 99032460 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 242 61 111 0 ENST00000413834.1:c.553C>T p.Pro185Ser p.P185S ENST00000413834 185 Ccg/Tcg 0 +ATP7B UCSF GRCh37 13 52544773 52544773 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 28 61 83 0 ENST00000242839.4:c.1398C>T p.Leu466= p.L466= ENST00000242839 NM_000053.3 466 ctC/ctT 0 +ATP8B4 UCSF GRCh37 15 50288947 50288947 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 22 26 0 ENST00000284509.6:c.516C>T p.Asn172= p.N172= ENST00000284509 NM_024837.3 172 aaC/aaT 0 +ATP9A UCSF GRCh37 20 50273508 50273508 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 21 23 0 ENST00000338821.5:c.1475G>A p.Cys492Tyr p.C492Y ENST00000338821 NM_006045.1 492 tGc/tAc 0 +ATRN UCSF GRCh37 20 3624813 3624813 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 53 106 0 ENST00000262919.5:c.4063C>T p.Pro1355Ser p.P1355S ENST00000262919 NM_139321.2 1355 Ccc/Tcc 0 +ATRX UCSF GRCh37 X 76875979 76875979 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 49 48 54 0 ENST00000373344.5:c.5156A>G p.Asp1719Gly p.D1719G ENST00000373344 NM_000489.3 1719 gAt/gGt 0 +ATXN3L UCSF GRCh37 X 13338003 13338003 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 94 192 0 ENST00000380622.2:c.51C>T p.His17= p.H17= ENST00000380622 NM_001135995.1 17 caC/caT 0 +ATXN7L2 UCSF GRCh37 1 110033657 110033657 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 65 40 0 ENST00000369870.3:c.1472G>A p.Arg491Lys p.R491K ENST00000369870 NM_153340.4 491 aGa/aAa 0 +ATXN7L2 UCSF GRCh37 1 110031543 110031543 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 49 51 0 ENST00000369870.3:c.858G>A p.Lys286= p.K286= ENST00000369870 NM_153340.4 286 aaG/aaA 0 +AUH UCSF GRCh37 9 93979608 93979608 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 14 48 0 ENST00000375731.4:c.845G>A p.Gly282Glu p.G282E ENST00000375731 NM_001698.2 282 gGa/gAa 0 +AUTS2 UCSF GRCh37 7 70254767 70254767 + synonymous_variant Silent SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 96 51 70 0 ENST00000342771.4:c.2565T>C p.Pro855= p.P855= ENST00000342771 NM_015570.2 855 ccT/ccC 0 +AVL9 UCSF GRCh37 7 32584392 32584392 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 9 28 0 ENST00000318709.4:c.300+1G>A p.X100_splice ENST00000318709 NM_015060.1 0 +AVL9 UCSF GRCh37 7 32598240 32598240 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 26 62 0 ENST00000318709.4:c.679G>A p.Gly227Ser p.G227S ENST00000318709 NM_015060.1 227 Ggc/Agc 0 +AXIN1 UCSF GRCh37 16 343703 343703 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 23 44 0 ENST00000262320.3:c.1971G>A p.Arg657= p.R657= ENST00000262320 NM_003502.3 657 agG/agA 0 +AZI1 UCSF GRCh37 17 79164773 79164773 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 43 28 0 ENST00000450824.2:c.2877G>A p.Glu959= p.E959= ENST00000450824 959 gaG/gaA 0 +AZI1 UCSF GRCh37 17 79193782 79193782 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 38 34 0 ENST00000450824.2:c.75C>T p.Leu25= p.L25= ENST00000450824 25 ctC/ctT 0 +B3GALT4 UCSF GRCh37 6 33246072 33246072 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 46 53 0 ENST00000451237.1:c.876C>T p.Val292= p.V292= ENST00000451237 NM_003782.3 292 gtC/gtT 0 +B4GALT4 UCSF GRCh37 3 118945752 118945752 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 12 39 0 ENST00000483209.1:c.390C>T p.His130= p.H130= ENST00000483209 130 caC/caT 0 +BACE1 UCSF GRCh37 11 117165989 117165989 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 36 53 0 ENST00000313005.6:c.425G>A p.Gly142Asp p.G142D ENST00000313005 NM_138971.3 142 gGc/gAc 0 +BAD UCSF GRCh37 11 64051683 64051683 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 65 58 25 0 ENST00000394532.3:c.158A>G p.Glu53Gly p.E53G ENST00000394532 NM_004322.3 53 gAg/gGg 0 +BAG3 UCSF GRCh37 10 121436297 121436297 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 34 67 0 ENST00000369085.3:c.1231G>A p.Gly411Arg p.G411R ENST00000369085 NM_004281.3 411 Gga/Aga 0 +BAHCC1 UCSF GRCh37 17 79426522 79426522 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 30 30 0 ENST00000307745.7:c.5797G>A p.Val1933Ile p.V1933I ENST00000307745 1933 Gtt/Att 0 +BAI3 UCSF GRCh37 6 69640470 69640470 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 25 17 24 0 ENST00000370598.1:c.777T>G p.Asp259Glu p.D259E ENST00000370598 NM_001704.2 259 gaT/gaG 0 +BAIAP2L1 UCSF GRCh37 7 97946557 97946557 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 216 74 147 0 ENST00000005260.8:c.460C>T p.Leu154Phe p.L154F ENST00000005260 NM_018842.4 154 Ctc/Ttc 0 +BAZ1B UCSF GRCh37 7 72892854 72892854 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 27 48 0 ENST00000339594.4:c.937C>T p.Pro313Ser p.P313S ENST00000339594 NM_032408.3 313 Cca/Tca 0 +BAZ2B UCSF GRCh37 2 160205734 160205734 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 22 41 0 ENST00000392783.2:c.4921G>A p.Val1641Ile p.V1641I ENST00000392783 NM_013450.2 1641 Gtt/Att 0 +BAZ2B UCSF GRCh37 2 160295520 160295520 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 113 62 97 0 ENST00000392783.2:c.900G>A p.Gln300= p.Q300= ENST00000392783 NM_013450.2 300 caG/caA 0 +BBS10 UCSF GRCh37 12 76741297 76741297 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 31 47 0 ENST00000393262.3:c.468C>T p.Ile156= p.I156= ENST00000393262 NM_024685.3 156 atC/atT 0 +BCAM UCSF GRCh37 19 45314506 45314506 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 39 59 0 ENST00000270233.6:c.107C>T p.Ser36Phe p.S36F ENST00000270233 NM_005581.4 36 tCt/tTt 0 +BCL11A UCSF GRCh37 2 60688616 60688616 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 25 15 0 ENST00000335712.6:c.1431C>T p.Asn477= p.N477= ENST00000335712 NM_022893.3 477 aaC/aaT 0 +BCL7C UCSF GRCh37 16 30905182 30905182 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 13 13 0 ENST00000215115.4:c.84C>T p.Val28= p.V28= ENST00000215115 NM_004765.2 28 gtC/gtT 0 +BCL9 UCSF GRCh37 1 147091456 147091456 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 53 60 0 ENST00000234739.3:c.1495G>A p.Asp499Asn p.D499N ENST00000234739 NM_004326.3 499 Gac/Aac 0 +BCMO1 UCSF GRCh37 16 81301516 81301516 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 24 31 0 ENST00000258168.2:c.623G>A p.Gly208Asp p.G208D ENST00000258168 NM_017429.2 208 gGc/gAc 0 +BCO2 UCSF GRCh37 11 112071473 112071473 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 47 102 0 ENST00000357685.5:c.1003G>A p.Val335Met p.V335M ENST00000357685 335 Gtg/Atg 0 +BCS1L UCSF GRCh37 2 219525867 219525867 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 59 81 0 ENST00000431802.1:c.157G>A p.Val53Ile p.V53I ENST00000431802 53 Gtc/Atc 0 +BDKRB1 UCSF GRCh37 14 96731073 96731073 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.00092 P05_Rec Untested WXS Illumina HiSeq 113 41 102 0 ENST00000216629.6:c.1054C>T p.Arg352Trp p.R352W ENST00000216629 NM_000710.3 352 Cgg/Tgg 0 +BEND2 UCSF GRCh37 X 18183192 18183192 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 70 93 0 ENST00000380033.4:c.2337C>T p.Thr779= p.T779= ENST00000380033 NM_153346.4 779 acC/acT 0 +BEST2 UCSF GRCh37 19 12866441 12866441 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 12 54 0 ENST00000549706.1:c.727G>A p.Ala243Thr p.A243T ENST00000549706 243 Gca/Aca 0 +BHLHB9 UCSF GRCh37 X 102004592 102004592 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 112 125 0 ENST00000372735.1:c.669C>T p.Ala223= p.A223= ENST00000372735 223 gcC/gcT 0 +BIN2 UCSF GRCh37 12 51685495 51685495 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 20 25 0 ENST00000267012.4:c.1395C>T p.Val465= p.V465= ENST00000267012 NM_016293.2 465 gtC/gtT 0 +BIRC6 UCSF GRCh37 2 32743376 32743376 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 65 126 0 ENST00000421745.2:c.11405G>A p.Gly3802Glu p.G3802E ENST00000421745 NM_016252.3 3802 gGg/gAg 0 +BIRC7 UCSF GRCh37 20 61869967 61869967 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 55 50 49 0 ENST00000217169.3:c.577+1G>A p.X193_splice ENST00000217169 NM_139317.2 0 +BLOC1S1 UCSF GRCh37 12 56110721 56110721 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 50 84 0 ENST00000548925.1:c.150G>A p.Lys50= p.K50= ENST00000548925 50 aaG/aaA 0 +BOD1L UCSF GRCh37 4 13597562 13597562 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 148 70 115 0 ENST00000040738.5:c.8026G>A p.Val2676Met p.V2676M ENST00000040738 NM_148894.2 2676 Gtg/Atg 0 +BPGM UCSF GRCh37 7 134346582 134346582 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 38 67 0 ENST00000393132.2:c.323G>A p.Gly108Asp p.G108D ENST00000393132 NM_199186.2 108 gGt/gAt 0 +BPIFA1 UCSF GRCh37 20 31829249 31829249 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 66 146 0 ENST00000354297.4:c.640G>A p.Val214Ile p.V214I ENST00000354297 NM_130852.2 214 Gtc/Atc 0 +BPTF UCSF GRCh37 17 65908699 65908699 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 115 49 110 0 ENST00000306378.6:c.4699C>T p.Leu1567= p.L1567= ENST00000306378 NM_182641.3 1567 Ctg/Ttg 0 +BRD3 UCSF GRCh37 9 136913446 136913446 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 112 42 30 0 ENST00000303407.7:c.845G>A p.Gly282Asp p.G282D ENST00000303407 NM_007371.3 282 gGt/gAt 0 +BRI3BP UCSF GRCh37 12 125509705 125509705 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 47 52 0 ENST00000341446.8:c.485G>A p.Arg162Gln p.R162Q ENST00000341446 NM_080626.5 162 cGg/cAg 0 +BRPF1 UCSF GRCh37 3 9785495 9785495 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 20 28 0 ENST00000383829.2:c.2545G>A p.Gly849Ser p.G849S ENST00000383829 NM_001003694.1 849 Ggt/Agt 0 +BRWD1 UCSF GRCh37 21 40601293 40601293 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 32 41 0 ENST00000333229.2:c.3070C>T p.Leu1024= p.L1024= ENST00000333229 NM_018963.4 1024 Cta/Tta 0 +BRWD1 UCSF GRCh37 21 40590459 40590459 + synonymous_variant Silent SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 32 46 0 ENST00000333229.2:c.3510C>A p.Ile1170= p.I1170= ENST00000333229 NM_018963.4 1170 atC/atA 0 +BRWD3 UCSF GRCh37 X 79989714 79989714 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 32 79 0 ENST00000373275.4:c.989G>A p.Gly330Asp p.G330D ENST00000373275 NM_153252.4 330 gGt/gAt 0 +BSN UCSF GRCh37 3 49689037 49689037 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 58 42 0 ENST00000296452.4:c.2048C>T p.Thr683Ile p.T683I ENST00000296452 NM_003458.3 683 aCa/aTa 0 +BSN UCSF GRCh37 3 49680541 49680541 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 20 26 0 ENST00000296452.4:c.1474G>A p.Val492Met p.V492M ENST00000296452 NM_003458.3 492 Gtg/Atg 0 +BSN UCSF GRCh37 3 49689614 49689614 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 19 25 0 ENST00000296452.4:c.2625G>A p.Gln875= p.Q875= ENST00000296452 NM_003458.3 875 caG/caA 0 +BTBD7 UCSF GRCh37 14 93712565 93712565 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 17 61 0 ENST00000334746.5:c.2189C>T p.Pro730Leu p.P730L ENST00000334746 NM_001002860.2 730 cCt/cTt 0 +BTG2 UCSF GRCh37 1 203276539 203276539 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 32 26 0 ENST00000290551.4:c.450G>A p.Lys150= p.K150= ENST00000290551 NM_006763.2 150 aaG/aaA 0 +C10orf10 UCSF GRCh37 10 45473337 45473337 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 55 39 0 ENST00000298295.3:c.142G>A p.Ala48Thr p.A48T ENST00000298295 NM_007021.3 48 Gca/Aca 0 +C10orf12 UCSF GRCh37 10 98744807 98744807 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 37 72 0 ENST00000286067.2:c.3660G>A p.Glu1220= p.E1220= ENST00000286067 NM_015652.2 1220 gaG/gaA 0 +C10orf120 UCSF GRCh37 10 124459240 124459240 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 33 61 0 ENST00000329446.4:c.67C>T p.Gln23Ter p.Q23* ENST00000329446 NM_001010912.2 23 Caa/Taa 0 +C10orf68 UCSF GRCh37 10 32983896 32983896 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 16 24 0 ENST00000302316.6:c.355C>T p.Leu119Phe p.L119F ENST00000302316 NM_024688.2 119 Ctt/Ttt 0 +C11orf66 UCSF GRCh37 11 61249350 61249350 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 34 17 0 ENST00000338608.2:c.69C>T p.Asp23= p.D23= ENST00000338608 NM_145017.2 23 gaC/gaT 0 +C12orf11 UCSF GRCh37 12 27077313 27077313 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 26 54 0 ENST00000261191.7:c.779C>T p.Thr260Ile p.T260I ENST00000261191 NM_018164.2 260 aCt/aTt 0 +C12orf11 UCSF GRCh37 12 27066981 27066981 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 33 29 0 ENST00000261191.7:c.1500C>T p.Asn500= p.N500= ENST00000261191 NM_018164.2 500 aaC/aaT 0 +C12orf51 UCSF GRCh37 12 112613626 112613626 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 160 33 126 1 ENST00000550722.1:c.11070C>T p.His3690= p.H3690= ENST00000550722 NM_001109662.3 3690 caC/caT 0 +C13orf27 UCSF GRCh37 13 103420646 103420646 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 25 56 56 0 ENST00000376032.4:c.262T>C p.Ser88Pro p.S88P ENST00000376032 NM_138779.3 88 Tca/Cca 0 +C14orf102 UCSF GRCh37 14 90770410 90770410 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 115 71 117 0 ENST00000354366.3:c.874G>A p.Glu292Lys p.E292K ENST00000354366 NM_017970.3 292 Gaa/Aaa 0 +C14orf28 UCSF GRCh37 14 45369727 45369727 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 36 74 0 ENST00000325192.3:c.89G>A p.Gly30Glu p.G30E ENST00000325192 NM_001017923.1 30 gGg/gAg 0 +C15orf27 UCSF GRCh37 15 76496215 76496215 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 56 57 0 ENST00000388942.3:c.1155C>T p.Thr385= p.T385= ENST00000388942 NM_152335.2 385 acC/acT 0 +C15orf33 UCSF GRCh37 15 49663565 49663565 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 122 63 102 0 ENST00000299338.6:c.1044C>T p.Asn348= p.N348= ENST00000299338 NM_152647.2 348 aaC/aaT 0 +C15orf55 UCSF GRCh37 15 34640819 34640819 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 47 77 0 ENST00000333756.4:c.666C>T p.Ala222= p.A222= ENST00000333756 NM_175741.1 222 gcC/gcT 0 +C16orf57 UCSF GRCh37 16 58043838 58043838 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 50 69 0 ENST00000219281.3:c.271G>A p.Ala91Thr p.A91T ENST00000219281 NM_024598.3 91 Gcc/Acc 0 +C16orf58 UCSF GRCh37 16 31510822 31510822 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 17 8 21 0 ENST00000327237.2:c.486G>A p.Lys162= p.K162= ENST00000327237 NM_022744.3 162 aaG/aaA 0 +C16orf71 UCSF GRCh37 16 4790360 4790360 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 47 28 0 ENST00000299320.5:c.483C>T p.Ser161= p.S161= ENST00000299320 NM_139170.2 161 tcC/tcT 0 +C17orf104 UCSF GRCh37 17 42745345 42745345 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 62 87 0 ENST00000409122.2:c.2066C>T p.Pro689Leu p.P689L ENST00000409122 NM_001145080.2 689 cCc/cTc 0 +C17orf74 UCSF GRCh37 17 7330099 7330099 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 45 35 0 ENST00000333870.3:c.789C>T p.Ser263= p.S263= ENST00000333870 NM_175734.4 263 tcC/tcT 0 +C17orf78 UCSF GRCh37 17 35745639 35745639 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 49 91 0 ENST00000300618.4:c.543G>A p.Trp181Ter p.W181* ENST00000300618 NM_173625.3 181 tgG/tgA 0 +C17orf80 UCSF GRCh37 17 71231716 71231716 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 26 58 0 ENST00000359042.2:c.95G>A p.Gly32Glu p.G32E ENST00000359042 NM_017941.4 32 gGa/gAa 0 +C17orf85 UCSF GRCh37 17 3721832 3721832 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 58 105 0 ENST00000389005.4:c.1035G>A p.Glu345= p.E345= ENST00000389005 NM_001114118.2 345 gaG/gaA 0 +C1orf116 UCSF GRCh37 1 207195526 207195526 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 22 30 0 ENST00000359470.5:c.1583C>T p.Pro528Leu p.P528L ENST00000359470 NM_023938.5 528 cCc/cTc 0 +C1orf55 UCSF GRCh37 1 226179064 226179064 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 25 60 0 ENST00000272091.7:c.521G>A p.Gly174Asp p.G174D ENST00000272091 NM_152608.3 174 gGt/gAt 0 +C20orf194 UCSF GRCh37 20 3275275 3275275 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 20 35 0 ENST00000252032.9:c.2019G>A p.Leu673= p.L673= ENST00000252032 NM_001009984.2 673 ttG/ttA 0 +C20orf20 UCSF GRCh37 20 61429976 61429976 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 225 154 137 0 ENST00000370487.3:c.308G>A p.Arg103Lys p.R103K ENST00000370487 NM_018270.4 103 aGg/aAg 0 +C20orf43 UCSF GRCh37 20 55092182 55092182 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 20 44 0 ENST00000023939.4:c.667G>A p.Val223Ile p.V223I ENST00000023939 NM_016407.3 223 Gtt/Att 0 +C21orf63 UCSF GRCh37 21 33887344 33887344 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 42 84 0 ENST00000300255.2:c.1170G>A p.Leu390= p.L390= ENST00000300255 NM_058187.3 390 ctG/ctA 0 +C2orf67 UCSF GRCh37 2 210889860 210889860 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 42 44 0 ENST00000281772.9:c.2532G>A p.Trp844Ter p.W844* ENST00000281772 NM_152519.2 844 tgG/tgA 0 +C3orf20 UCSF GRCh37 3 14799102 14799102 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 27 13 0 ENST00000253697.3:c.2165C>T p.Thr722Ile p.T722I ENST00000253697 NM_032137.4 722 aCc/aTc 0 +C3orf35 UCSF GRCh37 3 37459110 37459110 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 189 39 97 0 ENST00000328376.5:c.226+127G>A *76* ENST00000328376 NM_178339.2 0 +C4A UCSF GRCh37 6 31997482 31997482 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 132 31 97 0 ENST00000435363.2:c.3816C>T p.Leu1272= p.L1272= ENST00000435363 NM_001002029.3 1272 ctC/ctT 0 +C4orf40 UCSF GRCh37 4 71024297 71024297 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 129 88 122 0 ENST00000344526.5:c.328C>T p.Pro110Ser p.P110S ENST00000344526 NM_214711.3 110 Ccg/Tcg 0 +C5orf38 UCSF GRCh37 5 2752772 2752772 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 116 76 67 0 ENST00000334000.3:c.237C>T p.Tyr79= p.Y79= ENST00000334000 NM_178569.2 79 taC/taT 0 +C5orf42 UCSF GRCh37 5 37245866 37245866 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 38 37 0 ENST00000425232.2:c.163C>T p.Pro55Ser p.P55S ENST00000425232 NM_023073.3 55 Cct/Tct 0 +C5orf51 UCSF GRCh37 5 41917238 41917238 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 35 77 0 ENST00000381647.2:c.722G>A p.Gly241Glu p.G241E ENST00000381647 NM_175921.4 241 gGa/gAa 0 +C6orf103 UCSF GRCh37 6 147073673 147073673 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 27 69 0 ENST00000397944.3:c.3373G>A p.Val1125Ile p.V1125I ENST00000397944 NM_024694.3 1125 Gtt/Att 0 +C6orf106 UCSF GRCh37 6 34614419 34614419 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 52 97 0 ENST00000374023.3:c.470G>A p.Gly157Glu p.G157E ENST00000374023 NM_024294.2 157 gGa/gAa 0 +C6orf118 UCSF GRCh37 6 165703467 165703467 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 47 64 0 ENST00000230301.8:c.1210G>A p.Asp404Asn p.D404N ENST00000230301 NM_144980.3 404 Gat/Aat 0 +C6orf168 UCSF GRCh37 6 99771450 99771450 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 51 16 38 0 ENST00000389677.5:c.693G>A p.Arg231= p.R231= ENST00000389677 NM_032511.2 231 agG/agA 0 +C6orf27 UCSF GRCh37 6 31735267 31735267 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 65 111 0 ENST00000375688.4:c.1661G>A p.Gly554Asp p.G554D ENST00000375688 554 gGc/gAc 0 +C6orf48 UCSF GRCh37 6 31807392 31807392 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 36 85 0 ENST00000375640.3:c.180C>T p.Ser60= p.S60= ENST00000375640 NM_001040438.1 60 tcC/tcT 0 +C6orf97 UCSF GRCh37 6 151894324 151894324 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 28 69 0 ENST00000239374.7:c.790G>A p.Val264Ile p.V264I ENST00000239374 NM_025059.3 264 Gta/Ata 0 +C6orf97 UCSF GRCh37 6 151894326 151894326 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 74 28 72 0 ENST00000239374.7:c.792A>G p.Val264= p.V264= ENST00000239374 NM_025059.3 264 gtA/gtG 0 +C7orf30 UCSF GRCh37 7 23339170 23339170 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 3 12 0 ENST00000466681.1:c.199C>T p.Leu67= p.L67= ENST00000466681 NM_138446.1 67 Ctg/Ttg 0 +C7orf51 UCSF GRCh37 7 100085797 100085797 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 271 99 133 0 ENST00000300179.2:c.453G>A p.Glu151= p.E151= ENST00000300179 NM_173564.3 151 gaG/gaA 0 +C7orf58 UCSF GRCh37 7 120629737 120629737 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 144 66 0 ENST00000310396.5:c.62G>A p.Gly21Asp p.G21D ENST00000310396 NM_024913.4 21 gGc/gAc 0 +C7orf64 UCSF GRCh37 7 92158212 92158212 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 12 19 0 ENST00000265732.5:c.85G>A p.Glu29Lys p.E29K ENST00000265732 NM_032120.2 29 Gag/Aag 0 +C8A UCSF GRCh37 1 57373672 57373672 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 25 53 0 ENST00000361249.3:c.1266G>A p.Arg422= p.R422= ENST00000361249 NM_000562.2 422 cgG/cgA 0 +C8orf33 UCSF GRCh37 8 146278156 146278156 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 108 48 29 0 ENST00000331434.6:c.191G>A p.Gly64Asp p.G64D ENST00000331434 NM_023080.2 64 gGc/gAc 0 +C8orf34 UCSF GRCh37 8 69381015 69381015 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 32 81 0 ENST00000518698.1:c.696G>A p.Glu232= p.E232= ENST00000518698 NM_052958.2 232 gaG/gaA 0 +C8orf76 UCSF GRCh37 8 124243833 124243833 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 145 96 139 0 ENST00000276704.4:c.522C>T p.Tyr174= p.Y174= ENST00000276704 NM_032847.2 174 taC/taT 0 +C8orf80 UCSF GRCh37 8 27922104 27922104 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 119 79 128 0 ENST00000413272.2:c.856G>A p.Val286Ile p.V286I ENST00000413272 NM_001010906.1 286 Gtc/Atc 0 +C9orf117 UCSF GRCh37 9 130474170 130474170 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 13 9 0 ENST00000373295.2:c.927C>T p.Leu309= p.L309= ENST00000373295 NM_001012502.2 309 ctC/ctT 0 +C9orf152 UCSF GRCh37 9 112963293 112963293 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 35 81 0 ENST00000400613.4:c.655C>T p.Pro219Ser p.P219S ENST00000400613 NM_001012993.2 219 Ccc/Tcc 0 +C9orf152 UCSF GRCh37 9 112963491 112963491 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 52 136 0 ENST00000400613.4:c.457C>T p.Pro153Ser p.P153S ENST00000400613 NM_001012993.2 153 Cct/Tct 0 +C9orf50 UCSF GRCh37 9 132381915 132381915 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 198 74 57 0 ENST00000372478.4:c.600G>A p.Trp200Ter p.W200* ENST00000372478 NM_199350.3 200 tgG/tgA 0 +C9orf84 UCSF GRCh37 9 114454608 114454608 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 64 105 0 ENST00000374287.3:c.3457G>A p.Glu1153Lys p.E1153K ENST00000374287 1153 Gag/Aag 0 +C9orf84 UCSF GRCh37 9 114543245 114543245 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 15 46 0 ENST00000374287.3:c.30G>A p.Trp10Ter p.W10* ENST00000374287 10 tgG/tgA 0 +CA12 UCSF GRCh37 15 63618500 63618500 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 40 43 0 ENST00000178638.3:c.1049C>T p.Thr350Ile p.T350I ENST00000178638 NM_001218.3 350 aCt/aTt 0 +CABS1 UCSF GRCh37 4 71201897 71201897 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 55 37 69 0 ENST00000273936.5:c.1141G>A p.Asp381Asn p.D381N ENST00000273936 NM_033122.3 381 Gat/Aat 0 +CACNA1S UCSF GRCh37 1 201009472 201009472 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 22 20 0 ENST00000362061.3:c.5257G>A p.Asp1753Asn p.D1753N ENST00000362061 NM_000069.2 1753 Gac/Aac 0 +CACNA2D3 UCSF GRCh37 3 54661876 54661876 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 52 111 0 ENST00000474759.1:c.1026G>A p.Leu342= p.L342= ENST00000474759 NM_018398.2 342 ctG/ctA 0 +CADPS UCSF GRCh37 3 62648069 62648069 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 31 41 0 ENST00000383710.4:c.889C>T p.Leu297= p.L297= ENST00000383710 NM_003716.3 297 Ctg/Ttg 0 +CALB2 UCSF GRCh37 16 71416647 71416647 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 29 84 0 ENST00000302628.4:c.368G>A p.Arg123Lys p.R123K ENST00000302628 NM_001740.4 123 aGg/aAg 0 +CAMK1G UCSF GRCh37 1 209776620 209776620 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 21 43 0 ENST00000009105.1:c.283C>T p.Leu95= p.L95= ENST00000009105 95 Ctg/Ttg 0 +CAMSAP1 UCSF GRCh37 9 138773575 138773575 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 71 63 0 ENST00000389532.4:c.489G>A p.Glu163= p.E163= ENST00000389532 NM_015447.3 163 gaG/gaA 0 +CAMTA1 UCSF GRCh37 1 7737659 7737659 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 64 79 0 ENST00000303635.7:c.2780C>T p.Ala927Val p.A927V ENST00000303635 NM_015215.2 927 gCc/gTc 0 +CAPN1 UCSF GRCh37 11 64956121 64956121 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 35 35 0 ENST00000527323.1:c.1069G>A p.Ala357Thr p.A357T ENST00000527323 357 Gcc/Acc 0 +CAPN12 UCSF GRCh37 19 39224996 39224996 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 17 26 0 ENST00000328867.4:c.1778G>A p.Gly593Glu p.G593E ENST00000328867 NM_144691.3 593 gGg/gAg 0 +CAPN3 UCSF GRCh37 15 42703102 42703102 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 39 42 0 ENST00000397163.3:c.2284C>T p.Leu762Phe p.L762F ENST00000397163 NM_000070.2 762 Ctc/Ttc 0 +CAPS UCSF GRCh37 19 5914424 5914424 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 40 45 0 ENST00000222125.5:c.7G>A p.Ala3Thr p.A3T ENST00000222125 NM_004058.3 3 Gcc/Acc 0 +CAPZA2 UCSF GRCh37 7 116544243 116544243 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 166 34 74 0 ENST00000361183.3:c.232G>A p.Glu78Lys p.E78K ENST00000361183 NM_006136.2 78 Gaa/Aaa 0 +CARS UCSF GRCh37 11 3028128 3028128 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 98 97 0 ENST00000380525.4:c.2130G>A p.Val710= p.V710= ENST00000380525 NM_001194997.1 710 gtG/gtA 0 +CASP10 UCSF GRCh37 2 202060618 202060618 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 110 47 153 0 ENST00000286186.6:c.631G>A p.Glu211Lys p.E211K ENST00000286186 NM_032977.3 211 Gag/Aag 0 +CBL UCSF GRCh37 11 119169134 119169134 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 39 54 0 ENST00000264033.4:c.2318G>A p.Gly773Glu p.G773E ENST00000264033 NM_005188.3 773 gGg/gAg 0 +CBLB UCSF GRCh37 3 105400646 105400646 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 22 44 0 ENST00000264122.4:c.2218C>T p.His740Tyr p.H740Y ENST00000264122 NM_170662.3 740 Cac/Tac 0 +CBX1 UCSF GRCh37 17 46153525 46153525 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 23 55 0 ENST00000393408.3:c.156G>A p.Trp52Ter p.W52* ENST00000393408 NM_006807.4 52 tgG/tgA 0 +CC2D2A UCSF GRCh37 4 15569352 15569352 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 67 111 0 ENST00000424120.1:c.3341C>T p.Thr1114Met p.T1114M ENST00000424120 1114 aCg/aTg 0 +CC2D2A UCSF GRCh37 4 15538543 15538543 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 46 80 0 ENST00000424120.1:c.1608G>A p.Lys536= p.K536= ENST00000424120 536 aaG/aaA 0 +CCBE1 UCSF GRCh37 18 57105359 57105359 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 11 27 0 ENST00000439986.4:c.971G>A p.Gly324Glu p.G324E ENST00000439986 NM_133459.3 324 gGg/gAg 0 +CCDC102A UCSF GRCh37 16 57546657 57546657 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 45 29 0 ENST00000258214.2:c.1649C>T p.Ala550Val p.A550V ENST00000258214 NM_033212.3 550 gCc/gTc 0 +CCDC107 UCSF GRCh37 9 35660428 35660428 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 58 55 0 ENST00000426546.2:c.289G>A p.Glu97Lys p.E97K ENST00000426546 NM_001195201.1 97 Gag/Aag 0 +CCDC114 UCSF GRCh37 19 48806279 48806279 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 36 32 0 ENST00000315396.7:c.951G>A p.Glu317= p.E317= ENST00000315396 NM_144577.3 317 gaG/gaA 0 +CCDC134 UCSF GRCh37 22 42209290 42209290 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 38 59 0 ENST00000255784.5:c.333C>T p.Asn111= p.N111= ENST00000255784 NM_024821.2 111 aaC/aaT 0 +CCDC138 UCSF GRCh37 2 109410995 109410995 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 24 67 0 ENST00000295124.4:c.395-1G>A p.X132_splice ENST00000295124 NM_144978.1 0 +CCDC14 UCSF GRCh37 3 123680084 123680084 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 6 20 0 ENST00000433542.2:c.81G>A p.Ala27= p.A27= ENST00000433542 NM_022757.4 27 gcG/gcA 0 +CCDC146 UCSF GRCh37 7 76888377 76888377 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 15 15 0 ENST00000285871.4:c.750C>T p.Arg250= p.R250= ENST00000285871 NM_020879.2 250 cgC/cgT 0 +CCDC146 UCSF GRCh37 7 76924039 76924039 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 39 66 0 ENST00000285871.4:c.2724G>A p.Gln908= p.Q908= ENST00000285871 NM_020879.2 908 caG/caA 0 +CCDC149 UCSF GRCh37 4 24810101 24810101 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 38 34 0 ENST00000504487.1:c.1500G>A p.Glu500= p.E500= ENST00000504487 NM_001130726.2 500 gaG/gaA 0 +CCDC150 UCSF GRCh37 2 197595664 197595664 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 25 74 0 ENST00000389175.4:c.3064G>A p.Glu1022Lys p.E1022K ENST00000389175 NM_001080539.1 1022 Gaa/Aaa 0 +CCDC57 UCSF GRCh37 17 80156261 80156261 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 53 29 41 0 ENST00000392343.3:c.445T>C p.Tyr149His p.Y149H ENST00000392343 149 Tat/Cat 0 +CCDC57 UCSF GRCh37 17 80146139 80146139 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 32 20 0 ENST00000392343.3:c.1008G>A p.Trp336Ter p.W336* ENST00000392343 336 tgG/tgA 0 +CCDC57 UCSF GRCh37 17 80086473 80086473 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 24 17 0 ENST00000389641.4:c.2245G>A p.Asp749Asn p.D749N ENST00000389641 749 Gac/Aac 0 +CCDC60 UCSF GRCh37 12 119954456 119954456 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 11 46 0 ENST00000327554.2:c.912G>A p.Arg304= p.R304= ENST00000327554 NM_178499.3 304 cgG/cgA 0 +CCDC65 UCSF GRCh37 12 49310856 49310856 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 26 49 0 ENST00000320516.4:c.574G>A p.Glu192Lys p.E192K ENST00000320516 NM_033124.4 192 Gag/Aag 0 +CCDC66 UCSF GRCh37 3 56592873 56592873 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 22 23 0 ENST00000394672.3:c.12-1G>A p.X4_splice ENST00000394672 NM_001141947.1 0 +CCDC66 UCSF GRCh37 3 56651234 56651234 + synonymous_variant Silent SNP G G A snp132_rs114565523 P05_Rec Untested WXS Illumina HiSeq 62 19 50 0 ENST00000394672.3:c.1938G>A p.Ser646= p.S646= ENST00000394672 NM_001141947.1 646 tcG/tcA 0 +CCDC8 UCSF GRCh37 19 46914669 46914669 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 42 48 0 ENST00000307522.3:c.1399C>T p.Pro467Ser p.P467S ENST00000307522 NM_032040.4 467 Cca/Tca 0 +CCDC88A UCSF GRCh37 2 55522966 55522966 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 47 73 0 ENST00000336838.6:c.5315C>T p.Pro1772Leu p.P1772L ENST00000336838 1772 cCt/cTt 0 +CCDC88B UCSF GRCh37 11 64112135 64112135 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 16 11 0 ENST00000356786.5:c.2122G>A p.Val708Ile p.V708I ENST00000356786 NM_032251.5 708 Gtc/Atc 0 +CCNG2 UCSF GRCh37 4 78080624 78080624 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 58 59 0 ENST00000316355.5:c.243C>T p.Val81= p.V81= ENST00000316355 NM_004354.2 81 gtC/gtT 0 +CCNJL UCSF GRCh37 5 159680671 159680671 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 32 30 0 ENST00000393977.3:c.1022C>T p.Thr341Ile p.T341I ENST00000393977 NM_024565.5 341 aCc/aTc 0 +CCNT1 UCSF GRCh37 12 49087669 49087669 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 44 88 0 ENST00000261900.3:c.1328G>A p.Gly443Asp p.G443D ENST00000261900 NM_001240.3 443 gGt/gAt 0 +CCP110 UCSF GRCh37 16 19547481 19547481 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 48 81 0 ENST00000381396.5:c.490G>A p.Asp164Asn p.D164N ENST00000381396 NM_001199022.1 164 Gat/Aat 0 +CD109 UCSF GRCh37 6 74528156 74528156 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 28 39 0 ENST00000287097.5:c.3957C>T p.Asn1319= p.N1319= ENST00000287097 1319 aaC/aaT 0 +CD163 UCSF GRCh37 12 7647854 7647854 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 61 88 0 ENST00000359156.4:c.1243G>A p.Gly415Arg p.G415R ENST00000359156 NM_004244.5 415 Gga/Aga 0 +CD19 UCSF GRCh37 16 28943335 28943335 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 41 53 0 ENST00000538922.1:c.14G>A p.Arg5His p.R5H ENST00000538922 NM_001178098.1 5 cGc/cAc 0 +CD244 UCSF GRCh37 1 160802358 160802358 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 28 73 0 ENST00000368033.3:c.983C>T p.Ser328Phe p.S328F ENST00000368033 328 tCc/tTc 0 +CD244 UCSF GRCh37 1 160811234 160811234 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 40 77 0 ENST00000368033.3:c.436C>T p.Leu146= p.L146= ENST00000368033 146 Ctg/Ttg 0 +CD248 UCSF GRCh37 11 66083250 66083250 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 104 49 56 0 ENST00000311330.3:c.1249G>A p.Asp417Asn p.D417N ENST00000311330 NM_020404.2 417 Gac/Aac 0 +CD300LG UCSF GRCh37 17 41926176 41926176 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 34 65 0 ENST00000317310.4:c.294C>T p.Thr98= p.T98= ENST00000317310 NM_145273.3 98 acC/acT 0 +CD33 UCSF GRCh37 19 51728619 51728619 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 52 102 0 ENST00000262262.4:c.183C>T p.Phe61= p.F61= ENST00000262262 NM_001772.3 61 ttC/ttT 0 +CDC16 UCSF GRCh37 13 115037701 115037701 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 28 40 72 0 ENST00000360383.3:c.1646T>C p.Val549Ala p.V549A ENST00000360383 NM_001078645.1 549 gTg/gCg 0 +CDC27 UCSF GRCh37 17 45232117 45232117 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 48 65 0 ENST00000531206.1:c.878G>A p.Gly293Glu p.G293E ENST00000531206 293 gGa/gAa 0 +CDC42BPA UCSF GRCh37 1 227204712 227204712 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 45 88 0 ENST00000366769.3:c.4550G>A p.Ser1517Asn p.S1517N ENST00000366769 NM_003607.3 1517 aGt/aAt 0 +CDC42BPG UCSF GRCh37 11 64607621 64607621 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 26 23 0 ENST00000342711.5:c.552C>T p.His184= p.H184= ENST00000342711 NM_017525.2 184 caC/caT 0 +CDC42BPG UCSF GRCh37 11 64596944 64596944 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 22 14 0 ENST00000342711.5:c.3966G>A p.Trp1322Ter p.W1322* ENST00000342711 NM_017525.2 1322 tgG/tgA 0 +CDCA7 UCSF GRCh37 2 174229627 174229627 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0030 P05_Rec Untested WXS Illumina HiSeq 46 51 57 0 ENST00000306721.3:c.804G>A p.Gly268= p.G268= ENST00000306721 NM_031942.4 268 ggG/ggA 0 +CDCP2 UCSF GRCh37 1 54610301 54610301 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 25 32 0 ENST00000371330.1:c.265G>A p.Glu89Lys p.E89K ENST00000371330 NM_201546.3 89 Gag/Aag 0 +CDH1 UCSF GRCh37 16 68867309 68867309 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 30 70 0 ENST00000261769.5:c.2556G>A p.Glu852= p.E852= ENST00000261769 NM_004360.3 852 gaG/gaA 0 +CDH19 UCSF GRCh37 18 64235770 64235770 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 49 97 0 ENST00000262150.2:c.373G>A p.Gly125Arg p.G125R ENST00000262150 NM_021153.3 125 Gga/Aga 0 +CDH23 UCSF GRCh37 10 73434906 73434906 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.252,1000g2011may_all_0.28177,snp132_rs10999947 P05_Rec Untested WXS Illumina HiSeq 20 31 54 0 ENST00000224721.6:c.1502G>A p.Ser501Asn p.S501N ENST00000224721 NM_022124.5 501 aGc/aAc 0 +CDH24 UCSF GRCh37 14 23523978 23523978 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 43 47 0 ENST00000397359.3:c.594C>T p.Phe198= p.F198= ENST00000397359 NM_022478.3 198 ttC/ttT 0 +CDH8 UCSF GRCh37 16 61858915 61858915 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 53 82 0 ENST00000577390.1:c.835+1G>A p.X279_splice ENST00000577390 NM_001796.4 0 +CDH9 UCSF GRCh37 5 26886136 26886136 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 48 88 0 ENST00000231021.4:c.1569C>T p.Phe523= p.F523= ENST00000231021 NM_016279.3 523 ttC/ttT 0 +CDHR3 UCSF GRCh37 7 105624728 105624728 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 25 48 0 ENST00000317716.9:c.506C>T p.Pro169Leu p.P169L ENST00000317716 NM_152750.4 169 cCc/cTc 0 +CDK10 UCSF GRCh37 16 89755684 89755684 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 10 29 0 ENST00000353379.7:c.112G>A p.Glu38Lys p.E38K ENST00000353379 NM_052988.4 38 Gag/Aag 0 +CDK11A UCSF GRCh37 1 1634940 1634940 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 10 26 0 ENST00000404249.3:c.2035G>A p.Asp679Asn p.D679N ENST00000404249 NM_024011.2 679 Gac/Aac 0 +CDK11B UCSF GRCh37 1 1571841 1571841 + missense_variant,splice_region_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 75 11 40 0 ENST00000407249.3:c.1929T>G p.Asp643Glu p.D643E ENST00000407249 643 gaT/gaG 0 +CDK12 UCSF GRCh37 17 37667883 37667883 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 25 61 1 ENST00000447079.4:c.2768G>A p.Gly923Glu p.G923E ENST00000447079 NM_015083.1 923 gGa/gAa 0 +CDK13 UCSF GRCh37 7 40132563 40132563 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 176 70 161 0 ENST00000181839.4:c.3415G>A p.Gly1139Ser p.G1139S ENST00000181839 NM_031267.3 1139 Ggt/Agt 0 +CDK18 UCSF GRCh37 1 205495550 205495550 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 47 71 0 ENST00000506784.1:c.717C>T p.Ile239= p.I239= ENST00000506784 239 atC/atT 0 +CDK20 UCSF GRCh37 9 90585714 90585714 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 16 16 0 ENST00000325303.8:c.477C>T p.Leu159= p.L159= ENST00000325303 NM_001039803.2 159 ctC/ctT 0 +CDK4 UCSF GRCh37 12 58145092 58145092 + synonymous_variant Silent SNP G G A NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 118 44 87 0 ENST00000257904.6:c.252C>T p.Asp84= p.D84= ENST00000257904 NM_000075.3 84 gaC/gaT 0 +CDK6 UCSF GRCh37 7 92244504 92244504 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 35 10 36 0 ENST00000265734.4:c.931G>A p.Asp311Asn p.D311N ENST00000265734 NM_001259.6 311 Gat/Aat 0 +CDKN2A UCSF GRCh37 9 21971017 21971017 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 25 34 23 0 ENST00000304494.5:c.341C>T p.Pro114Leu p.P114L ENST00000304494 NM_000077.4 114 cCc/cTc 0 +CDYL2 UCSF GRCh37 16 80654695 80654695 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 18 42 0 ENST00000570137.2:c.972G>A p.Arg324= p.R324= ENST00000570137 NM_152342.2 324 cgG/cgA 0 +CEACAM16 UCSF GRCh37 19 45208927 45208927 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 46 71 0 ENST00000587331.1:c.729C>T p.Asp243= p.D243= ENST00000587331 NM_001039213.2 243 gaC/gaT 0 +CEACAM5 UCSF GRCh37 19 42224071 42224071 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 121 81 185 0 ENST00000221992.6:c.1715G>A p.Gly572Glu p.G572E ENST00000221992 NM_004363.2 572 gGa/gAa 0 +CECR2 UCSF GRCh37 22 18018789 18018789 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 133 106 179 0 ENST00000262608.8:c.1413G>A p.Lys471= p.K471= ENST00000262608 NM_031413.3 471 aaG/aaA 0 +CELF2 UCSF GRCh37 10 11367840 11367840 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 43 70 0 ENST00000450189.1:c.1336G>A p.Glu446Lys p.E446K ENST00000450189 NM_006561.3 446 Gaa/Aaa 0 +CELF4 UCSF GRCh37 18 34850748 34850748 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 22 40 0 ENST00000420428.2:c.1082G>A p.Gly361Asp p.G361D ENST00000420428 NM_020180.3 361 gGc/gAc 0 +CELSR1 UCSF GRCh37 22 46794525 46794525 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 26 30 0 ENST00000262738.3:c.5422G>A p.Asp1808Asn p.D1808N ENST00000262738 NM_014246.1 1808 Gat/Aat 0 +CELSR3 UCSF GRCh37 3 48677633 48677633 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 40 28 0 ENST00000164024.4:c.9385G>A p.Asp3129Asn p.D3129N ENST00000164024 NM_001407.2 3129 Gac/Aac 0 +CENPE UCSF GRCh37 4 104102587 104102587 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 28 33 0 ENST00000265148.3:c.990G>A p.Lys330= p.K330= ENST00000265148 NM_001813.2 330 aaG/aaA 0 +CENPJ UCSF GRCh37 13 25458563 25458563 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 24 52 0 ENST00000381884.4:c.3516G>A p.Leu1172= p.L1172= ENST00000381884 NM_018451.4 1172 ctG/ctA 0 +CENPT UCSF GRCh37 16 67865247 67865247 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 32 52 0 ENST00000562787.1:c.575C>T p.Thr192Ile p.T192I ENST00000562787 NM_025082.3 192 aCc/aTc 0 +CEP104 UCSF GRCh37 1 3768942 3768942 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 27 36 0 ENST00000378230.3:c.30C>T p.Val10= p.V10= ENST00000378230 NM_014704.3 10 gtC/gtT 0 +CEP128 UCSF GRCh37 14 80993238 80993238 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 22 52 0 ENST00000555265.1:c.3047C>T p.Thr1016Ile p.T1016I ENST00000555265 1016 aCc/aTc 0 +CEP250 UCSF GRCh37 20 34057745 34057745 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 61 62 0 ENST00000397527.1:c.882G>A p.Gln294= p.Q294= ENST00000397527 NM_007186.3 294 caG/caA 0 +CEP290 UCSF GRCh37 12 88505548 88505548 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 25 23 0 ENST00000552810.1:c.2140G>A p.Glu714Lys p.E714K ENST00000552810 NM_025114.3 714 Gaa/Aaa 0 +CHAC1 UCSF GRCh37 15 41247886 41247886 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 65 35 0 ENST00000446533.3:c.709G>A p.Asp237Asn p.D237N ENST00000446533 NM_024111.3 237 Gac/Aac 0 +CHD1L UCSF GRCh37 1 146740464 146740464 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 22 31 0 ENST00000369258.4:c.1012G>A p.Val338Ile p.V338I ENST00000369258 NM_001256336.1 338 Gtt/Att 0 +CHD5 UCSF GRCh37 1 6211163 6211163 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 25 60 0 ENST00000262450.3:c.923G>A p.Ser308Asn p.S308N ENST00000262450 NM_015557.2 308 aGt/aAt 0 +CHD8 UCSF GRCh37 14 21870663 21870663 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 26 114 0 ENST00000399982.2:c.3715-1G>A p.X1239_splice ENST00000399982 NM_001170629.1 0 +CHI3L2 UCSF GRCh37 1 111781386 111781386 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 32 82 0 ENST00000445067.2:c.750G>A p.Gly250= p.G250= ENST00000445067 250 ggG/ggA 0 +CHRD UCSF GRCh37 3 184107167 184107167 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 8 8 23 0 ENST00000204604.1:c.2825C>T p.Thr942Ile p.T942I ENST00000204604 NM_003741.2 942 aCc/aTc 0 +CHRM1 UCSF GRCh37 11 62677223 62677223 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 85 30 0 ENST00000306960.3:c.1350C>T p.Gly450= p.G450= ENST00000306960 NM_000738.2 450 ggC/ggT 0 +CHRM3 UCSF GRCh37 1 240071285 240071285 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 63 110 0 ENST00000255380.4:c.534C>T p.Ala178= p.A178= ENST00000255380 NM_000740.2 178 gcC/gcT 0 +CHRM5 UCSF GRCh37 15 34355661 34355661 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 84 94 0 ENST00000383263.5:c.743C>T p.Ala248Val p.A248V ENST00000383263 NM_012125.3 248 gCt/gTt 0 +CHRNA2 UCSF GRCh37 8 27320517 27320517 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 153 88 63 0 ENST00000407991.1:c.1443G>A p.Arg481= p.R481= ENST00000407991 NM_000742.3 481 cgG/cgA 0 +CHRNE UCSF GRCh37 17 4802823 4802823 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 17 10 0 ENST00000293780.4:c.972C>T p.Ile324= p.I324= ENST00000293780 NM_000080.3 324 atC/atT 0 +CHTOP UCSF GRCh37 1 153610925 153610925 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 28 75 0 ENST00000368694.3:c.219+1G>A p.X73_splice ENST00000368694 NM_001206612.1 0 +CHURC1-FNTB UCSF GRCh37 14 65507588 65507588 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 32 81 0 ENST00000246166.2:c.773C>T p.Ala258Val p.A258V ENST00000246166 NM_002028.3 258 gCg/gTg 0 +CIDEC UCSF GRCh37 3 9911904 9911904 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 23 51 0 ENST00000430427.1:c.340G>A p.Asp114Asn p.D114N ENST00000430427 NM_001199551.1 114 Gat/Aat 0 +CIDEC UCSF GRCh37 3 9911985 9911985 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 33 68 1 ENST00000430427.1:c.259G>A p.Ala87Thr p.A87T ENST00000430427 NM_001199551.1 87 Gca/Aca 0 +CIT UCSF GRCh37 12 120148087 120148087 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 68 62 99 0 ENST00000392521.2:c.5040C>G p.Ile1680Met p.I1680M ENST00000392521 NM_001206999.1 1680 atC/atG 0 +CIT UCSF GRCh37 12 120198744 120198744 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 158 37 133 0 ENST00000392521.2:c.2420C>T p.Ala807Val p.A807V ENST00000392521 NM_001206999.1 807 gCg/gTg 0 +CLASRP UCSF GRCh37 19 45563647 45563647 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 30 37 0 ENST00000221455.3:c.711G>A p.Arg237= p.R237= ENST00000221455 NM_007056.2 237 agG/agA 0 +CLCA4 UCSF GRCh37 1 87041026 87041026 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 33 67 0 ENST00000370563.3:c.1695G>A p.Trp565Ter p.W565* ENST00000370563 NM_012128.3 565 tgG/tgA 0 +CLCN2 UCSF GRCh37 3 184071508 184071508 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 9 9 0 ENST00000265593.4:c.1797C>T p.Asp599= p.D599= ENST00000265593 NM_004366.5 599 gaC/gaT 0 +CLCN6 UCSF GRCh37 1 11897461 11897461 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 120 66 71 0 ENST00000346436.6:c.2200G>A p.Glu734Lys p.E734K ENST00000346436 NM_001286.3 734 Gag/Aag 0 +CLCN7 UCSF GRCh37 16 1505749 1505749 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 44 21 35 0 ENST00000382745.4:c.964T>C p.Phe322Leu p.F322L ENST00000382745 NM_001287.5 322 Ttc/Ctc 0 +CLDN12 UCSF GRCh37 7 90042082 90042082 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 152 52 97 0 ENST00000535571.1:c.92C>T p.Pro31Leu p.P31L ENST00000535571 NM_001185072.2 31 cCc/cTc 0 +CLDN14 UCSF GRCh37 21 37833860 37833860 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 13 12 0 ENST00000399137.1:c.134C>T p.Ser45Phe p.S45F ENST00000399137 NM_144492.2 45 tCc/tTc 0 +CLDN25 UCSF GRCh37 11 113651156 113651156 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 44 57 0 ENST00000453129.2:c.639G>A p.Glu213= p.E213= ENST00000453129 NM_001101389.1 213 gaG/gaA 0 +CLDN3 UCSF GRCh37 7 73183997 73183997 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 24 14 0 ENST00000395145.2:c.383C>T p.Ala128Val p.A128V ENST00000395145 NM_001306.3 128 gCc/gTc 0 +CLEC14A UCSF GRCh37 14 38723923 38723923 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 46 61 0 ENST00000342213.2:c.1305G>A p.Lys435= p.K435= ENST00000342213 NM_175060.2 435 aaG/aaA 0 +CLEC4F UCSF GRCh37 2 71046551 71046551 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 5 28 0 ENST00000272367.2:c.204G>A p.Pro68= p.P68= ENST00000272367 NM_001258027.1 68 ccG/ccA 0 +CLIC2 UCSF GRCh37 X 154528171 154528171 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 20 46 56 0 ENST00000369449.2:c.220G>A p.Val74Met p.V74M ENST00000369449 NM_001289.4 74 Gtg/Atg 0 +CLIC3 UCSF GRCh37 9 139889703 139889703 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 30 13 0 ENST00000494426.1:c.311C>T p.Ala104Val p.A104V ENST00000494426 NM_004669.2 104 gCc/gTc 0 +CLIP1 UCSF GRCh37 12 122825965 122825965 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 167 57 143 0 ENST00000540338.1:c.1786G>A p.Glu596Lys p.E596K ENST00000540338 596 Gaa/Aaa 0 +CLMN UCSF GRCh37 14 95688111 95688111 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 12 40 0 ENST00000298912.4:c.241C>T p.Leu81= p.L81= ENST00000298912 NM_024734.3 81 Ctg/Ttg 0 +CLOCK UCSF GRCh37 4 56308688 56308688 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 29 45 0 ENST00000309964.4:c.2016C>T p.Ala672= p.A672= ENST00000309964 NM_004898.3 672 gcC/gcT 0 +CLPB UCSF GRCh37 11 72012915 72012915 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 96 136 0 ENST00000294053.3:c.1351G>A p.Val451Met p.V451M ENST00000294053 NM_001258394.1 451 Gtg/Atg 0 +CLPTM1L UCSF GRCh37 5 1339018 1339018 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 43 30 0 ENST00000320895.5:c.556G>A p.Asp186Asn p.D186N ENST00000320895 NM_030782.3 186 Gac/Aac 0 +CLPX UCSF GRCh37 15 65459022 65459022 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 68 111 0 ENST00000300107.3:c.460G>A p.Ala154Thr p.A154T ENST00000300107 NM_006660.3 154 Gca/Aca 0 +CLTCL1 UCSF GRCh37 22 19222138 19222138 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 59 133 0 ENST00000263200.10:c.1061G>A p.Arg354His p.R354H ENST00000263200 NM_007098.3 354 cGt/cAt 0 +CMTM7 UCSF GRCh37 3 32493943 32493943 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 135 42 112 0 ENST00000334983.5:c.492C>G p.Ile164Met p.I164M ENST00000334983 NM_138410.2 164 atC/atG 0 +CNGA1 UCSF GRCh37 4 47939410 47939410 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 77 163 0 ENST00000402813.3:c.1308C>T p.Pro436= p.P436= ENST00000402813 436 ccC/ccT 0 +CNGB1 UCSF GRCh37 16 57921761 57921761 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 52 70 0 ENST00000251102.8:c.3460C>T p.Gln1154Ter p.Q1154* ENST00000251102 NM_001297.4 1154 Cag/Tag 0 +CNKSR1 UCSF GRCh37 1 26510576 26510576 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 51 36 59 0 ENST00000361530.6:c.870C>T p.Val290= p.V290= ENST00000361530 290 gtC/gtT 0 +CNOT10 UCSF GRCh37 3 32761616 32761616 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 32 50 0 ENST00000454516.2:c.935C>T p.Ser312Phe p.S312F ENST00000454516 NM_001256742.1 312 tCt/tTt 0 +CNOT2 UCSF GRCh37 12 70739975 70739975 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 32 74 0 ENST00000229195.3:c.1407G>A p.Trp469Ter p.W469* ENST00000229195 NM_014515.5 469 tgG/tgA 0 +CNTN4 UCSF GRCh37 3 2967424 2967424 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 120 64 110 0 ENST00000397461.1:c.1319C>T p.Thr440Ile p.T440I ENST00000397461 NM_001206955.1 440 aCc/aTc 0 +CNTNAP2 UCSF GRCh37 7 147092808 147092808 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 69 97 0 ENST00000361727.3:c.1606G>A p.Val536Met p.V536M ENST00000361727 NM_014141.5 536 Gtg/Atg 0 +CNTNAP2 UCSF GRCh37 7 146471385 146471385 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 9 18 0 ENST00000361727.3:c.120C>T p.Val40= p.V40= ENST00000361727 NM_014141.5 40 gtC/gtT 0 +CNTNAP3 UCSF GRCh37 9 39109170 39109170 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 43 127 0 ENST00000297668.6:c.2352C>T p.Leu784= p.L784= ENST00000297668 NM_033655.3 784 ctC/ctT 0 +CNTRL UCSF GRCh37 9 123922424 123922424 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 35 52 0 ENST00000373855.1:c.4933G>A p.Val1645Ile p.V1645I ENST00000373855 1645 Gta/Ata 0 +COG7 UCSF GRCh37 16 23409437 23409437 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 12 26 0 ENST00000307149.5:c.1817C>T p.Ala606Val p.A606V ENST00000307149 NM_153603.3 606 gCt/gTt 0 +COL11A1 UCSF GRCh37 1 103467488 103467488 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 27 62 0 ENST00000370096.3:c.2135G>A p.Gly712Asp p.G712D ENST00000370096 NM_001854.3 712 gGt/gAt 0 +COL11A2 UCSF GRCh37 6 33156946 33156946 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 20 43 0 ENST00000374708.4:c.252C>T p.Phe84= p.F84= ENST00000374708 NM_080681.2 84 ttC/ttT 0 +COL15A1 UCSF GRCh37 9 101785659 101785659 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 5 9 0 ENST00000375001.3:c.1782C>T p.Gly594= p.G594= ENST00000375001 NM_001855.4 594 ggC/ggT 0 +COL16A1 UCSF GRCh37 1 32120459 32120459 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 149 82 107 0 ENST00000373672.3:c.4291G>A p.Gly1431Arg p.G1431R ENST00000373672 NM_001856.3 1431 Gga/Aga 0 +COL1A1 UCSF GRCh37 17 48271324 48271324 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 24 49 0 ENST00000225964.5:c.1747C>T p.Pro583Ser p.P583S ENST00000225964 NM_000088.3 583 Cct/Tct 0 +COL28A1 UCSF GRCh37 7 7400059 7400059 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 18 51 0 ENST00000399429.3:c.3167C>T p.Pro1056Leu p.P1056L ENST00000399429 NM_001037763.2 1056 cCc/cTc 0 +COL2A1 UCSF GRCh37 12 48388219 48388219 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 7 23 0 ENST00000380518.3:c.804G>A p.Pro268= p.P268= ENST00000380518 NM_033150.2 268 ccG/ccA 0 +COL3A1 UCSF GRCh37 2 189855065 189855065 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 16 37 0 ENST00000304636.3:c.777C>T p.Phe259= p.F259= ENST00000304636 NM_000090.3 259 ttC/ttT 0 +COL5A1 UCSF GRCh37 9 137646141 137646141 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 30 35 0 ENST00000371817.3:c.1796C>T p.Pro599Leu p.P599L ENST00000371817 NM_001278074.1 599 cCg/cTg 0 +COL5A1 UCSF GRCh37 9 137727017 137727017 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 19 16 0 ENST00000371817.3:c.5337C>T p.Asn1779= p.N1779= ENST00000371817 NM_001278074.1 1779 aaC/aaT 0 +COL5A2 UCSF GRCh37 2 189928723 189928723 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 14 15 0 ENST00000374866.3:c.1753G>A p.Gly585Arg p.G585R ENST00000374866 NM_000393.3 585 Gga/Aga 0 +COL5A3 UCSF GRCh37 19 10116849 10116849 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 18 14 0 ENST00000264828.3:c.147G>A p.Glu49= p.E49= ENST00000264828 NM_015719.3 49 gaG/gaA 0 +COL7A1 UCSF GRCh37 3 48618048 48618048 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 14 17 0 ENST00000328333.8:c.5018G>A p.Gly1673Glu p.G1673E ENST00000328333 NM_000094.3 1673 gGa/gAa 0 +COL7A1 UCSF GRCh37 3 48623045 48623045 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 112 42 80 0 ENST00000328333.8:c.3839C>T p.Thr1280Ile p.T1280I ENST00000328333 NM_000094.3 1280 aCc/aTc 0 +COL7A1 UCSF GRCh37 3 48610990 48610990 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 21 52 0 ENST00000328333.8:c.6574G>A p.Gly2192Ser p.G2192S ENST00000328333 NM_000094.3 2192 Ggt/Agt 0 +COMP UCSF GRCh37 19 18900034 18900034 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 5 9 0 ENST00000222271.2:c.463C>T p.Pro155Ser p.P155S ENST00000222271 NM_000095.2 155 Ccg/Tcg 0 +COPG2 UCSF GRCh37 7 130297051 130297051 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 39 52 0 ENST00000445977.2:c.551C>T p.Ala184Val p.A184V ENST00000445977 184 gCt/gTt 0 +COQ10B UCSF GRCh37 2 198327456 198327456 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 40 92 0 ENST00000263960.2:c.447+1G>A p.X149_splice ENST00000263960 NM_025147.3 0 +CORO1B UCSF GRCh37 11 67210034 67210034 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 56 42 0 ENST00000393893.1:c.66C>T p.Asn22= p.N22= ENST00000393893 NM_001018070.2 22 aaC/aaT 0 +CPA1 UCSF GRCh37 7 130024402 130024402 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 31 59 0 ENST00000011292.3:c.722C>T p.Ser241Phe p.S241F ENST00000011292 NM_001868.2 241 tCc/tTc 0 +CPA2 UCSF GRCh37 7 129910532 129910532 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 26 48 0 ENST00000222481.4:c.289-1G>A p.X97_splice ENST00000222481 NM_001869.2 0 +CPA6 UCSF GRCh37 8 68423853 68423853 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 135 83 171 0 ENST00000297770.4:c.355G>A p.Gly119Arg p.G119R ENST00000297770 NM_020361.4 119 Gga/Aga 0 +CPEB2 UCSF GRCh37 4 15067995 15067995 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 24 20 0 ENST00000538197.1:c.3096C>T p.Arg1032= p.R1032= ENST00000538197 NM_001177382.1 1032 cgC/cgT 0 +CPLX4 UCSF GRCh37 18 56963995 56963995 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 15 48 0 ENST00000299721.3:c.418G>A p.Glu140Lys p.E140K ENST00000299721 NM_181654.3 140 Gaa/Aaa 0 +CPN1 UCSF GRCh37 10 101841302 101841302 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 18 36 0 ENST00000370418.3:c.81C>T p.Arg27= p.R27= ENST00000370418 NM_001308.2 27 cgC/cgT 0 +CPNE4 UCSF GRCh37 3 131261584 131261584 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 20 75 0 ENST00000512055.1:c.1356C>T p.Asp452= p.D452= ENST00000512055 452 gaC/gaT 0 +CPNE7 UCSF GRCh37 16 89655150 89655150 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 20 18 0 ENST00000268720.5:c.1220C>T p.Pro407Leu p.P407L ENST00000268720 NM_014427.4 407 cCc/cTc 0 +CPNE7 UCSF GRCh37 16 89655121 89655121 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 19 20 0 ENST00000268720.5:c.1191G>A p.Arg397= p.R397= ENST00000268720 NM_014427.4 397 cgG/cgA 0 +CPNE9 UCSF GRCh37 3 9759751 9759751 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 24 62 0 ENST00000383832.3:c.970C>T p.Pro324Ser p.P324S ENST00000383832 NM_153635.2 324 Ccc/Tcc 0 +CPO UCSF GRCh37 2 207827203 207827203 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 52 94 0 ENST00000272852.3:c.642G>A p.Glu214= p.E214= ENST00000272852 NM_173077.2 214 gaG/gaA 0 +CPS1 UCSF GRCh37 2 211540487 211540487 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 30 47 0 ENST00000430249.2:c.4215C>T p.Asn1405= p.N1405= ENST00000430249 NM_001122633.2 1405 aaC/aaT 0 +CPSF2 UCSF GRCh37 14 92625468 92625468 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 29 102 0 ENST00000298875.4:c.1963G>A p.Asp655Asn p.D655N ENST00000298875 NM_017437.2 655 Gat/Aat 0 +CPSF3 UCSF GRCh37 2 9568931 9568931 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 32 21 0 ENST00000238112.3:c.88C>T p.Leu30Phe p.L30F ENST00000238112 NM_016207.3 30 Ctc/Ttc 0 +CR2 UCSF GRCh37 1 207644796 207644796 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 28 72 0 ENST00000367057.3:c.1522G>A p.Glu508Lys p.E508K ENST00000367057 NM_001006658.2 508 Gag/Aag 0 +CRB1 UCSF GRCh37 1 197297784 197297784 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 29 48 0 ENST00000367400.3:c.303G>A p.Gly101= p.G101= ENST00000367400 NM_201253.2 101 ggG/ggA 0 +CRB2 UCSF GRCh37 9 126133407 126133407 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 195 136 98 0 ENST00000373631.3:c.1986C>T p.Leu662= p.L662= ENST00000373631 NM_173689.5 662 ctC/ctT 0 +CREB3L3 UCSF GRCh37 19 4157196 4157196 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 32 36 0 ENST00000078445.2:c.361G>A p.Gly121Arg p.G121R ENST00000078445 NM_032607.2 121 Ggg/Agg 0 +CREB5 UCSF GRCh37 7 28527801 28527801 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 173 51 96 0 ENST00000357727.2:c.12G>A p.Glu4= p.E4= ENST00000357727 NM_182898.2 4 gaG/gaA 0 +CREBBP UCSF GRCh37 16 3900677 3900677 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 38 40 0 ENST00000262367.5:c.419C>T p.Thr140Ile p.T140I ENST00000262367 NM_004380.2 140 aCc/aTc 0 +CRHR2 UCSF GRCh37 7 30702446 30702446 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 18 25 0 ENST00000348438.4:c.642C>T p.Ile214= p.I214= ENST00000348438 NM_001202475.1 214 atC/atT 0 +CRNN UCSF GRCh37 1 152384651 152384651 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 43 79 0 ENST00000271835.3:c.59G>A p.Arg20Lys p.R20K ENST00000271835 NM_016190.2 20 aGg/aAg 0 +CROCC UCSF GRCh37 1 17263217 17263217 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 17 11 0 ENST00000375541.5:c.1042C>T p.Leu348= p.L348= ENST00000375541 NM_014675.3 348 Ctg/Ttg 0 +CRTC2 UCSF GRCh37 1 153930932 153930932 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 18 9 0 ENST00000368633.1:c.42C>T p.Ala14= p.A14= ENST00000368633 NM_181715.2 14 gcC/gcT 0 +CRTC3 UCSF GRCh37 15 91184367 91184367 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 18 31 0 ENST00000268184.6:c.1587C>T p.Asp529= p.D529= ENST00000268184 529 gaC/gaT 0 +CRYGS UCSF GRCh37 3 186257318 186257318 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 31 38 0 ENST00000392499.2:c.90C>T p.Phe30= p.F30= ENST00000392499 NM_017541.2 30 ttC/ttT 0 +CSNK1A1L UCSF GRCh37 13 37678549 37678549 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 149 85 162 0 ENST00000379800.3:c.845G>A p.Arg282His p.R282H ENST00000379800 NM_145203.5 282 cGc/cAc 0 +CTBS UCSF GRCh37 1 85020795 85020795 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 45 77 0 ENST00000370630.5:c.1045C>T p.Arg349Trp p.R349W ENST00000370630 NM_004388.2 349 Cgg/Tgg 0 +CTNNA1 UCSF GRCh37 5 138223181 138223181 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 43 98 0 ENST00000302763.7:c.1146C>T p.Leu382= p.L382= ENST00000302763 NM_001903.2 382 ctC/ctT 0 +CTNNA2 UCSF GRCh37 2 79971605 79971605 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 21 33 0 ENST00000466387.1:c.195G>A p.Glu65= p.E65= ENST00000466387 65 gaG/gaA 0 +CTTNBP2 UCSF GRCh37 7 117417811 117417811 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 156 69 0 ENST00000160373.3:c.2532G>A p.Trp844Ter p.W844* ENST00000160373 NM_033427.2 844 tgG/tgA 0 +CTU2 UCSF GRCh37 16 88780546 88780546 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 26 27 0 ENST00000453996.2:c.1008C>T p.Ala336= p.A336= ENST00000453996 NM_001012759.1 336 gcC/gcT 0 +CUBN UCSF GRCh37 10 17126431 17126431 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 33 46 0 ENST00000377833.4:c.2140G>A p.Asp714Asn p.D714N ENST00000377833 NM_001081.3 714 Gac/Aac 0 +CUL9 UCSF GRCh37 6 43155750 43155750 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 18 55 0 ENST00000252050.4:c.1881G>A p.Lys627= p.K627= ENST00000252050 NM_015089.2 627 aaG/aaA 0 +CWC27 UCSF GRCh37 5 64096076 64096076 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 26 55 0 ENST00000381070.3:c.671G>A p.Ser224Asn p.S224N ENST00000381070 NM_005869.2 224 aGc/aAc 0 +CWF19L1 UCSF GRCh37 10 102016038 102016038 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 42 58 0 ENST00000354105.4:c.485G>A p.Gly162Glu p.G162E ENST00000354105 NM_018294.4 162 gGg/gAg 0 +CWH43 UCSF GRCh37 4 49032932 49032932 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 56 110 0 ENST00000226432.4:c.1463G>A p.Gly488Asp p.G488D ENST00000226432 NM_025087.2 488 gGt/gAt 0 +CWH43 UCSF GRCh37 4 49032978 49032978 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 58 117 0 ENST00000226432.4:c.1508+1G>A p.X503_splice ENST00000226432 NM_025087.2 0 +CXXC1 UCSF GRCh37 18 47812419 47812419 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 129 71 58 0 ENST00000412036.2:c.432G>A p.Pro144= p.P144= ENST00000412036 144 ccG/ccA 0 +CYB5R2 UCSF GRCh37 11 7686718 7686718 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 14 19 23 0 ENST00000533558.1:c.718C>T p.Pro240Ser p.P240S ENST00000533558 240 Cca/Tca 0 +CYFIP1 UCSF GRCh37 15 22999357 22999357 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 32 41 0 ENST00000313077.7:c.3229G>A p.Glu1077Lys p.E1077K ENST00000313077 NM_014608.2 1077 Gag/Aag 0 +CYHR1 UCSF GRCh37 8 145689659 145689659 + intron_variant Intron DEL C C - NOVEL P05_Rec Untested WXS Illumina HiSeq 6 0 ENST00000438911.2:c.246+184del *82* ENST00000438911 NM_138496.1 0 +CYLC1 UCSF GRCh37 X 83128720 83128720 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 37 80 0 ENST00000329312.4:c.1004C>T p.Ala335Val p.A335V ENST00000329312 NM_021118.2 335 gCt/gTt 0 +CYLC1 UCSF GRCh37 X 83128100 83128100 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 25 41 0 ENST00000329312.4:c.384G>A p.Lys128= p.K128= ENST00000329312 NM_021118.2 128 aaG/aaA 0 +CYP1A1 UCSF GRCh37 15 75013789 75013789 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 31 58 0 ENST00000379727.3:c.1008C>T p.Asn336= p.N336= ENST00000379727 336 aaC/aaT 0 +CYP46A1 UCSF GRCh37 14 100184439 100184439 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 14 51 0 ENST00000261835.3:c.956C>T p.Ser319Phe p.S319F ENST00000261835 NM_006668.1 319 tCt/tTt 0 +CYP4X1 UCSF GRCh37 1 47501585 47501585 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 42 84 0 ENST00000371901.3:c.600G>A p.Glu200= p.E200= ENST00000371901 NM_178033.1 200 gaG/gaA 0 +DAGLA UCSF GRCh37 11 61495691 61495691 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 72 46 0 ENST00000257215.5:c.703G>A p.Asp235Asn p.D235N ENST00000257215 NM_006133.2 235 Gac/Aac 0 +DAO UCSF GRCh37 12 109290787 109290787 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 14 61 0 ENST00000228476.3:c.618C>T p.Asp206= p.D206= ENST00000228476 NM_001917.4 206 gaC/gaT 0 +DAPK1 UCSF GRCh37 9 90252979 90252979 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 25 67 0 ENST00000408954.3:c.406G>A p.Ala136Thr p.A136T ENST00000408954 NM_004938.2 136 Gcc/Acc 0 +DAXX UCSF GRCh37 6 33289312 33289312 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 94 61 67 0 ENST00000374542.5:c.240C>T p.Asp80= p.D80= ENST00000374542 NM_001141970.1 80 gaC/gaT 0 +DBH UCSF GRCh37 9 136513028 136513028 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0020,snp132_rs75215331 P05_Rec Untested WXS Illumina HiSeq 52 21 30 0 ENST00000393056.2:c.1085C>T p.Ala362Val p.A362V ENST00000393056 NM_000787.3 362 gCg/gTg 0 +DBH UCSF GRCh37 9 136523486 136523486 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 172 61 33 0 ENST00000393056.2:c.1771G>A p.Glu591Lys p.E591K ENST00000393056 NM_000787.3 591 Gag/Aag 0 +DCAF17 UCSF GRCh37 2 172337616 172337616 + missense_variant Missense_Mutation SNP A A T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 47 84 0 ENST00000375255.3:c.1555A>T p.Ser519Cys p.S519C ENST00000375255 NM_025000.3 519 Agc/Tgc 0 +DCAF4 UCSF GRCh37 14 73406608 73406608 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 17 6 12 0 ENST00000358377.2:c.191C>T p.Pro64Leu p.P64L ENST00000358377 NM_001163509.1 64 cCa/cTa 0 +DCAF4 UCSF GRCh37 14 73425453 73425453 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 56 54 0 ENST00000358377.2:c.1428G>A p.Arg476= p.R476= ENST00000358377 NM_001163509.1 476 cgG/cgA 0 +DCAF4L2 UCSF GRCh37 8 88885864 88885864 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 122 66 75 0 ENST00000319675.3:c.336C>T p.Leu112= p.L112= ENST00000319675 NM_152418.3 112 ctC/ctT 0 +DCAF5 UCSF GRCh37 14 69520872 69520872 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 25 41 0 ENST00000341516.5:c.2531C>T p.Pro844Leu p.P844L ENST00000341516 NM_003861.2 844 cCt/cTt 0 +DCAF6 UCSF GRCh37 1 168035641 168035641 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 34 16 0 ENST00000367840.3:c.2623G>A p.Asp875Asn p.D875N ENST00000367840 NM_001198956.1 875 Gac/Aac 0 +DCAF7 UCSF GRCh37 17 61661012 61661012 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 94 57 98 0 ENST00000415273.2:c.139-1561G>A *47* ENST00000415273 0 +DCC UCSF GRCh37 18 50731599 50731599 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 167 86 153 0 ENST00000442544.2:c.1587G>A p.Gly529= p.G529= ENST00000442544 NM_005215.3 529 ggG/ggA 0 +DCHS2 UCSF GRCh37 4 155157309 155157309 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 46 69 0 ENST00000357232.4:c.7130G>A p.Gly2377Glu p.G2377E ENST00000357232 NM_017639.3 2377 gGg/gAg 0 +DDAH2 UCSF GRCh37 6 31696918 31696918 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 79 56 43 0 ENST00000375789.2:c.21G>A p.Gly7= p.G7= ENST00000375789 7 ggG/ggA 0 +DDB1 UCSF GRCh37 11 61089873 61089873 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 36 90 0 ENST00000301764.7:c.1017C>T p.Asp339= p.D339= ENST00000301764 NM_001923.4 339 gaC/gaT 0 +DDHD1 UCSF GRCh37 14 53513646 53513646 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 39 34 58 0 ENST00000323669.5:c.2543A>C p.Asp848Ala p.D848A ENST00000323669 NM_001160148.1 848 gAt/gCt 0 +DDN UCSF GRCh37 12 49390988 49390988 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 7 11 0 ENST00000421952.2:c.1671C>T p.Asn557= p.N557= ENST00000421952 NM_015086.1 557 aaC/aaT 0 +DDX10 UCSF GRCh37 11 108547856 108547856 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 51 80 0 ENST00000322536.3:c.423G>A p.Gly141= p.G141= ENST00000322536 NM_004398.2 141 ggG/ggA 0 +DDX11 UCSF GRCh37 12 31237978 31237978 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.161,1000g2011may_all_0.2074,snp132_rs74087925 P05_Rec Untested WXS Illumina HiSeq 37 14 16 1 ENST00000407793.2:c.556C>T p.Arg186Trp p.R186W ENST00000407793 NM_030653.3 186 Cgg/Tgg 0 +DDX11 UCSF GRCh37 12 31236773 31236773 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 86 122 0 ENST00000407793.2:c.171G>A p.Gly57= p.G57= ENST00000407793 NM_030653.3 57 ggG/ggA 0 +DDX39A UCSF GRCh37 19 14520440 14520440 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 46 44 1 ENST00000242776.4:c.882G>A p.Lys294= p.K294= ENST00000242776 NM_005804.3 294 aaG/aaA 0 +DDX42 UCSF GRCh37 17 61894274 61894274 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 12 52 0 ENST00000578681.1:c.2060C>T p.Pro687Leu p.P687L ENST00000578681 NM_007372.3 687 cCt/cTt 0 +DDX42 UCSF GRCh37 17 61894288 61894288 + missense_variant Missense_Mutation SNP A A T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 11 47 0 ENST00000578681.1:c.2074A>T p.Met692Leu p.M692L ENST00000578681 NM_007372.3 692 Atg/Ttg 0 +DDX55 UCSF GRCh37 12 124093278 124093278 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 47 103 0 ENST00000238146.4:c.453G>A p.Arg151= p.R151= ENST00000238146 NM_020936.1 151 agG/agA 0 +DEM1 UCSF GRCh37 1 40980565 40980565 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 51 87 0 ENST00000372703.1:c.349G>A p.Gly117Ser p.G117S ENST00000372703 117 Ggt/Agt 0 +DENND1A UCSF GRCh37 9 126554866 126554866 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 20 34 0 ENST00000373624.2:c.132G>A p.Gln44= p.Q44= ENST00000373624 NM_020946.1 44 caG/caA 0 +DENND2C UCSF GRCh37 1 115151491 115151491 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 24 71 0 ENST00000393274.1:c.1373G>A p.Arg458His p.R458H ENST00000393274 NM_001256404.1 458 cGc/cAc 0 +DENND3 UCSF GRCh37 8 142175334 142175334 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 47 92 0 ENST00000262585.2:c.1259G>A p.Arg420Lys p.R420K ENST00000262585 NM_014957.2 420 aGg/aAg 0 +DENND3 UCSF GRCh37 8 142151382 142151382 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 44 39 0 ENST00000262585.2:c.342C>T p.Ser114= p.S114= ENST00000262585 NM_014957.2 114 tcC/tcT 0 +DENND4C UCSF GRCh37 9 19372071 19372071 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 73 94 0 ENST00000602925.1:c.5630G>A p.Ser1877Asn p.S1877N ENST00000602925 NM_017925.5 1877 aGt/aAt 0 +DGCR2 UCSF GRCh37 22 19026602 19026602 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 28 26 0 ENST00000263196.7:c.1429C>T p.Leu477= p.L477= ENST00000263196 NM_001184781.1 477 Ctg/Ttg 0 +DHCR7 UCSF GRCh37 11 71149986 71149986 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 37 21 0 ENST00000355527.3:c.770C>T p.Ala257Val p.A257V ENST00000355527 NM_001360.2 257 gCg/gTg 0 +DHRS2 UCSF GRCh37 14 24108207 24108207 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 110 110 71 0 ENST00000344777.7:c.134C>T p.Thr45Ile p.T45I ENST00000344777 NM_182908.4 45 aCc/aTc 0 +DHTKD1 UCSF GRCh37 10 12136143 12136143 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 31 72 0 ENST00000263035.4:c.1231C>T p.Leu411= p.L411= ENST00000263035 NM_018706.6 411 Ctg/Ttg 0 +DHX37 UCSF GRCh37 12 125460028 125460028 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 19 23 0 ENST00000308736.2:c.917C>T p.Pro306Leu p.P306L ENST00000308736 NM_032656.3 306 cCc/cTc 0 +DIAPH1 UCSF GRCh37 5 140953776 140953776 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 20 27 0 ENST00000398557.4:c.1642-1G>A p.X548_splice ENST00000398557 NM_005219.4 0 +DIDO1 UCSF GRCh37 20 61528154 61528154 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 63 48 0 ENST00000266070.4:c.1783C>T p.Pro595Ser p.P595S ENST00000266070 NM_033081.2 595 Ccc/Tcc 0 +DIO1 UCSF GRCh37 1 54371821 54371821 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 22 40 0 ENST00000361921.3:c.535G>A p.Asp179Asn p.D179N ENST00000361921 NM_213593.3 179 Gat/Aat 0 +DIO3 UCSF GRCh37 14 102027864 102027864 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 18 16 0 ENST00000510508.4:c.31G>A p.Val11Ile p.V11I ENST00000510508 11 Gtc/Atc 0 +DIP2A UCSF GRCh37 21 47978178 47978178 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 32 17 0 ENST00000417564.2:c.3841G>A p.Val1281Ile p.V1281I ENST00000417564 1281 Gtc/Atc 0 +DIP2C UCSF GRCh37 10 518451 518451 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 55 34 0 ENST00000280886.6:c.196G>A p.Val66Ile p.V66I ENST00000280886 NM_014974.2 66 Gtc/Atc 0 +DISC1 UCSF GRCh37 1 232144796 232144796 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 46 74 0 ENST00000439617.2:c.2307+1G>A p.X769_splice ENST00000439617 NM_001164540.1 0 +DLC1 UCSF GRCh37 8 12957327 12957327 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 50 57 0 ENST00000276297.4:c.2519C>T p.Thr840Met p.T840M ENST00000276297 NM_182643.2 840 aCg/aTg 0 +DLG3 UCSF GRCh37 X 69670031 69670031 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 15 18 0 ENST00000374360.3:c.716G>A p.Ser239Asn p.S239N ENST00000374360 NM_021120.3 239 aGc/aAc 0 +DMXL2 UCSF GRCh37 15 51773611 51773611 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 167 89 115 0 ENST00000543779.2:c.5692C>T p.Pro1898Ser p.P1898S ENST00000543779 1898 Cct/Tct 0 +DNAAF1 UCSF GRCh37 16 84211350 84211350 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 114 54 44 0 ENST00000378553.5:c.2081C>T p.Ala694Val p.A694V ENST00000378553 NM_178452.4 694 gCc/gTc 0 +DNAH1 UCSF GRCh37 3 52430684 52430684 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.003,1000g2011may_all_0.0054 P05_Rec Untested WXS Illumina HiSeq 88 21 83 0 ENST00000420323.2:c.11481C>T p.Asn3827= p.N3827= ENST00000420323 NM_015512.4 3827 aaC/aaT 0 +DNAH10 UCSF GRCh37 12 124285920 124285920 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 62 102 0 ENST00000409039.3:c.2201C>T p.Ser734Phe p.S734F ENST00000409039 NM_207437.3 734 tCc/tTc 0 +DNAH10 UCSF GRCh37 12 124401178 124401178 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 155 56 99 0 ENST00000409039.3:c.10543G>A p.Glu3515Lys p.E3515K ENST00000409039 NM_207437.3 3515 Gaa/Aaa 0 +DNAH10 UCSF GRCh37 12 124352656 124352656 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 20 33 0 ENST00000409039.3:c.7155G>A p.Gly2385= p.G2385= ENST00000409039 NM_207437.3 2385 ggG/ggA 0 +DNAH12 UCSF GRCh37 3 57356463 57356463 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 111 33 102 0 ENST00000344804.4:c.727C>T p.Pro243Ser p.P243S ENST00000344804 243 Ccc/Tcc 0 +DNAH14 UCSF GRCh37 1 225152200 225152200 + synonymous_variant Silent SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 63 42 60 0 ENST00000400952.3:c.387G>C p.Val129= p.V129= ENST00000400952 NM_001145154.1 129 gtG/gtC 0 +DNAH17 UCSF GRCh37 17 76554320 76554320 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 42 128 0 ENST00000389840.5:c.2048G>A p.Arg683Lys p.R683K ENST00000389840 683 aGa/aAa 0 +DNAH17 UCSF GRCh37 17 76421649 76421649 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 38 17 0 ENST00000389840.5:c.12988C>T p.Leu4330Phe p.L4330F ENST00000389840 4330 Ctc/Ttc 0 +DNAH2 UCSF GRCh37 17 7691239 7691239 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 46 51 0 ENST00000572933.1:c.6665G>A p.Cys2222Tyr p.C2222Y ENST00000572933 2222 tGc/tAc 0 +DNAH5 UCSF GRCh37 5 13891220 13891220 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 56 98 0 ENST00000265104.4:c.2442G>A p.Glu814= p.E814= ENST00000265104 NM_001369.2 814 gaG/gaA 0 +DNAH6 UCSF GRCh37 2 84931258 84931258 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 52 105 0 ENST00000389394.3:c.8297C>T p.Ala2766Val p.A2766V ENST00000389394 NM_001370.1 2766 gCt/gTt 0 +DNAH6 UCSF GRCh37 2 84848345 84848345 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 31 43 0 ENST00000389394.3:c.3823G>A p.Gly1275Ser p.G1275S ENST00000389394 NM_001370.1 1275 Ggc/Agc 0 +DNAH6 UCSF GRCh37 2 84915694 84915694 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 30 61 0 ENST00000389394.3:c.7269G>A p.Gln2423= p.Q2423= ENST00000389394 NM_001370.1 2423 caG/caA 0 +DNAH7 UCSF GRCh37 2 196738340 196738340 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 38 71 0 ENST00000312428.6:c.6365C>T p.Ser2122Phe p.S2122F ENST00000312428 NM_018897.2 2122 tCc/tTc 0 +DNAJC18 UCSF GRCh37 5 138755754 138755754 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 39 110 0 ENST00000302060.5:c.940G>A p.Glu314Lys p.E314K ENST00000302060 NM_152686.3 314 Gag/Aag 0 +DNAJC21 UCSF GRCh37 5 34945016 34945016 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 187 109 172 0 ENST00000382021.2:c.1028C>T p.Ala343Val p.A343V ENST00000382021 NM_194283.3 343 gCc/gTc 0 +DOCK11 UCSF GRCh37 X 117752562 117752562 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 42 82 0 ENST00000276202.7:c.3342C>T p.Phe1114= p.F1114= ENST00000276202 NM_144658.3 1114 ttC/ttT 0 +DOCK4 UCSF GRCh37 7 111387342 111387342 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 240 81 201 0 ENST00000437633.1:c.4547G>A p.Gly1516Asp p.G1516D ENST00000437633 NM_014705.3 1516 gGc/gAc 0 +DOCK4 UCSF GRCh37 7 111382189 111382189 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 161 78 123 0 ENST00000437633.1:c.4651-1G>A p.X1551_splice ENST00000437633 NM_014705.3 0 +DOCK6 UCSF GRCh37 19 11363181 11363181 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 125 68 134 0 ENST00000294618.7:c.354G>A p.Glu118= p.E118= ENST00000294618 NM_020812.3 118 gaG/gaA 0 +DOCK6 UCSF GRCh37 19 11325298 11325298 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 27 61 0 ENST00000294618.7:c.4134C>T p.Ala1378= p.A1378= ENST00000294618 NM_020812.3 1378 gcC/gcT 0 +DOCK6 UCSF GRCh37 19 11339673 11339673 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 13 17 0 ENST00000294618.7:c.2757C>T p.Ser919= p.S919= ENST00000294618 NM_020812.3 919 agC/agT 0 +DOLPP1 UCSF GRCh37 9 131847523 131847523 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 198 66 88 0 ENST00000372546.4:c.300C>T p.Pro100= p.P100= ENST00000372546 NM_020438.4 100 ccC/ccT 0 +DPH5 UCSF GRCh37 1 101458296 101458296 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 34 65 0 ENST00000370109.3:c.531G>A p.Lys177= p.K177= ENST00000370109 NM_001077395.1 177 aaG/aaA 0 +DPP4 UCSF GRCh37 2 162929997 162929997 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 35 36 0 ENST00000360534.3:c.7-1G>A p.X3_splice ENST00000360534 NM_001935.3 0 +DPP6 UCSF GRCh37 7 154679444 154679444 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 224 88 198 0 ENST00000377770.3:c.2304G>A p.Glu768= p.E768= ENST00000377770 768 gaG/gaA 0 +DPYD UCSF GRCh37 1 97544641 97544641 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 67 135 0 ENST00000370192.3:c.2969C>T p.Thr990Ile p.T990I ENST00000370192 NM_000110.3 990 aCt/aTt 0 +DRAP1 UCSF GRCh37 11 65688075 65688075 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 43 25 0 ENST00000312515.2:c.365G>A p.Gly122Asp p.G122D ENST00000312515 NM_006442.3 122 gGt/gAt 0 +DRD5 UCSF GRCh37 4 9784541 9784541 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 147 80 62 0 ENST00000304374.2:c.888G>A p.Lys296= p.K296= ENST00000304374 NM_000798.4 296 aaG/aaA 0 +DRG2 UCSF GRCh37 17 18005276 18005276 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 11 14 0 ENST00000225729.3:c.771C>T p.Asp257= p.D257= ENST00000225729 NM_001388.4 257 gaC/gaT 0 +DSC2 UCSF GRCh37 18 28672242 28672242 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 30 70 0 ENST00000280904.6:c.176C>T p.Thr59Ile p.T59I ENST00000280904 NM_024422.3 59 aCa/aTa 0 +DSCR6 UCSF GRCh37 21 38390293 38390293 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 15 27 0 ENST00000329553.2:c.359C>T p.Ala120Val p.A120V ENST00000329553 NM_018962.2 120 gCt/gTt 0 +DSG2 UCSF GRCh37 18 29121213 29121213 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 24 47 0 ENST00000261590.8:c.1937C>T p.Pro646Leu p.P646L ENST00000261590 NM_001943.3 646 cCc/cTc 0 +DST UCSF GRCh37 6 56362671 56362671 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 131 62 141 0 ENST00000244364.6:c.12208G>A p.Asp4070Asn p.D4070N ENST00000244364 NM_015548.4 4070 Gat/Aat 0 +DST UCSF GRCh37 6 56365995 56365995 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 129 64 136 0 ENST00000244364.6:c.11910C>T p.Phe3970= p.F3970= ENST00000244364 NM_015548.4 3970 ttC/ttT 0 +DTNA UCSF GRCh37 18 32455243 32455243 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 24 47 0 ENST00000598334.1:c.1523C>T p.Thr508Ile p.T508I ENST00000598334 NM_001198938.1 508 aCc/aTc 0 +DTX1 UCSF GRCh37 12 113496108 113496108 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 25 16 0 ENST00000257600.3:c.111G>A p.Trp37Ter p.W37* ENST00000257600 NM_004416.2 37 tgG/tgA 0 +DTX2 UCSF GRCh37 7 76132849 76132849 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 21 48 0 ENST00000324432.5:c.1496G>A p.Gly499Asp p.G499D ENST00000324432 NM_020892.2 499 gGc/gAc 0 +DUOX1 UCSF GRCh37 15 45434294 45434294 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 31 50 0 ENST00000321429.4:c.1806C>T p.Leu602= p.L602= ENST00000321429 NM_017434.3 602 ctC/ctT 0 +DUOXA2 UCSF GRCh37 15 45408829 45408829 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 59 24 0 ENST00000323030.5:c.456C>T p.Asp152= p.D152= ENST00000323030 NM_207581.3 152 gaC/gaT 0 +DUSP16 UCSF GRCh37 12 12633232 12633232 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 44 91 0 ENST00000228862.2:c.740G>A p.Gly247Glu p.G247E ENST00000228862 NM_030640.2 247 gGg/gAg 0 +DVL1 UCSF GRCh37 1 1273693 1273693 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 31 21 0 ENST00000378891.5:c.1388C>T p.Thr463Ile p.T463I ENST00000378891 NM_004421.2 463 aCc/aTc 0 +DVL3 UCSF GRCh37 3 183887949 183887949 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 26 24 0 ENST00000313143.3:c.1654G>A p.Gly552Ser p.G552S ENST00000313143 NM_004423.3 552 Ggc/Agc 0 +DYNC1H1 UCSF GRCh37 14 102515847 102515847 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 45 27 0 ENST00000360184.4:c.13443C>T p.Asp4481= p.D4481= ENST00000360184 NM_001376.4 4481 gaC/gaT 0 +DYRK4 UCSF GRCh37 12 4719397 4719397 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 26 61 0 ENST00000540757.2:c.1092G>A p.Met364Ile p.M364I ENST00000540757 NM_003845.1 364 atG/atA 0 +DZIP1 UCSF GRCh37 13 96239920 96239920 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 33 49 0 ENST00000347108.3:c.2091C>T p.Ser697= p.S697= ENST00000347108 697 tcC/tcT 0 +E2F7 UCSF GRCh37 12 77417858 77417858 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 29 67 0 ENST00000322886.7:c.2673C>T p.Asn891= p.N891= ENST00000322886 NM_203394.2 891 aaC/aaT 0 +ECM1 UCSF GRCh37 1 150483675 150483675 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 104 53 84 0 ENST00000369049.4:c.789+1G>A p.X263_splice ENST00000369049 NM_001202858.1 0 +ECT2L UCSF GRCh37 6 139164281 139164281 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 36 85 0 ENST00000423192.1:c.508C>T p.Pro170Ser p.P170S ENST00000423192 170 Ccc/Tcc 0 +EDEM1 UCSF GRCh37 3 5252860 5252860 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 195 70 126 0 ENST00000256497.4:c.1639G>A p.Glu547Lys p.E547K ENST00000256497 NM_014674.2 547 Gag/Aag 0 +EDEM3 UCSF GRCh37 1 184679682 184679682 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 40 82 0 ENST00000318130.8:c.1692-1G>A p.X564_splice ENST00000318130 NM_025191.3 0 +EDF1 UCSF GRCh37 9 139758304 139758304 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 27 63 0 ENST00000224073.1:c.98G>A p.Arg33Lys p.R33K ENST00000224073 NM_001281298.1 33 aGa/aAa 0 +EEA1 UCSF GRCh37 12 93196237 93196237 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 33 38 0 ENST00000322349.8:c.2613C>T p.Asn871= p.N871= ENST00000322349 NM_003566.3 871 aaC/aaT 0 +EFNA1 UCSF GRCh37 1 155106219 155106219 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 58 79 0 ENST00000368407.3:c.468G>A p.Gln156= p.Q156= ENST00000368407 NM_004428.2 156 caG/caA 0 +EFNB2 UCSF GRCh37 13 107145608 107145608 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 66 57 0 ENST00000245323.4:c.782C>T p.Pro261Leu p.P261L ENST00000245323 NM_004093.3 261 cCg/cTg 0 +EHMT1 UCSF GRCh37 9 140672342 140672342 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 254 89 112 0 ENST00000460843.1:c.2027G>A p.Gly676Glu p.G676E ENST00000460843 NM_024757.4 676 gGg/gAg 0 +EHMT1 UCSF GRCh37 9 140652417 140652417 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 57 74 0 ENST00000460843.1:c.1455C>T p.Asp485= p.D485= ENST00000460843 NM_024757.4 485 gaC/gaT 0 +EHMT2 UCSF GRCh37 6 31864759 31864759 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 148 18 47 0 ENST00000375537.4:c.50C>A p.Ala17Asp p.A17D ENST00000375537 NM_006709.3 17 gCc/gAc 0 +EI24 UCSF GRCh37 11 125445200 125445200 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 6 16 0 ENST00000278903.6:c.84G>A p.Lys28= p.K28= ENST00000278903 NM_004879.3 28 aaG/aaA 0 +EIF2AK1 UCSF GRCh37 7 6066478 6066478 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 46 98 0 ENST00000199389.6:c.1645C>T p.Leu549Phe p.L549F ENST00000199389 NM_001134335.1 549 Ctc/Ttc 0 +EIF2S2 UCSF GRCh37 20 32693260 32693260 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 44 94 0 ENST00000374980.2:c.107C>T p.Thr36Ile p.T36I ENST00000374980 NM_003908.3 36 aCc/aTc 0 +EIF3B UCSF GRCh37 7 2418387 2418387 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 27 6 30 0 ENST00000360876.4:c.2218T>C p.Ser740Pro p.S740P ENST00000360876 NM_001037283.1 740 Tcc/Ccc 0 +EIF3K UCSF GRCh37 19 39123092 39123092 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 147 64 153 0 ENST00000248342.4:c.377A>G p.Asp126Gly p.D126G ENST00000248342 NM_013234.2 126 gAc/gGc 0 +EIF6 UCSF GRCh37 20 33872225 33872225 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 201 101 39 0 ENST00000374450.3:c.66C>T p.Thr22= p.T22= ENST00000374450 NM_002212.3 22 acC/acT 0 +ELL UCSF GRCh37 19 18569095 18569095 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 23 36 0 ENST00000262809.4:c.789C>T p.Asp263= p.D263= ENST00000262809 NM_006532.3 263 gaC/gaT 0 +ELMO1 UCSF GRCh37 7 37251060 37251060 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 23 63 0 ENST00000310758.4:c.1017C>T p.Asn339= p.N339= ENST00000310758 NM_014800.10 339 aaC/aaT 0 +EMILIN2 UCSF GRCh37 18 2913251 2913251 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 48 31 39 0 ENST00000254528.3:c.3011G>A p.Gly1004Asp p.G1004D ENST00000254528 NM_032048.2 1004 gGc/gAc 0 +EML5 UCSF GRCh37 14 89160752 89160752 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 46 92 0 ENST00000554922.1:c.2439-1G>A p.X813_splice ENST00000554922 NM_183387.2 0 +ENAM UCSF GRCh37 4 71508053 71508053 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 41 90 0 ENST00000396073.3:c.910G>A p.Gly304Arg p.G304R ENST00000396073 NM_031889.2 304 Gga/Aga 0 +ENAM UCSF GRCh37 4 71508405 71508405 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 110 78 103 0 ENST00000396073.3:c.1262G>A p.Gly421Asp p.G421D ENST00000396073 NM_031889.2 421 gGt/gAt 0 +ENC1 UCSF GRCh37 5 73931072 73931072 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 28 39 0 ENST00000302351.4:c.1239G>A p.Gln413= p.Q413= ENST00000302351 NM_003633.3 413 caG/caA 0 +ENO2 UCSF GRCh37 12 7030820 7030820 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 43 72 0 ENST00000535366.1:c.942G>A p.Gln314= p.Q314= ENST00000535366 314 caG/caA 0 +ENPEP UCSF GRCh37 4 111452380 111452380 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 20 24 0 ENST00000265162.5:c.1754G>A p.Trp585Ter p.W585* ENST00000265162 NM_001977.3 585 tGg/tAg 0 +ENPP2 UCSF GRCh37 8 120569856 120569856 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 57 61 0 ENST00000259486.6:c.2653C>T p.Leu885Phe p.L885F ENST00000259486 NM_006209.4 885 Ctc/Ttc 0 +ENPP7 UCSF GRCh37 17 77707389 77707389 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 28 27 0 ENST00000328313.5:c.337C>T p.Leu113= p.L113= ENST00000328313 NM_178543.3 113 Ctg/Ttg 0 +EP400 UCSF GRCh37 12 132466904 132466904 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 152 57 53 0 ENST00000389561.2:c.1810C>T p.Pro604Ser p.P604S ENST00000389561 NM_015409.4 604 Cct/Tct 0 +EPB41L1 UCSF GRCh37 20 34785820 34785820 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 27 32 0 ENST00000338074.2:c.1525G>A p.Ala509Thr p.A509T ENST00000338074 NM_012156.2 509 Gcc/Acc 0 +EPB41L4B UCSF GRCh37 9 111965992 111965992 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 40 89 0 ENST00000374566.3:c.1897C>T p.Pro633Ser p.P633S ENST00000374566 NM_019114.3 633 Ccg/Tcg 0 +EPB42 UCSF GRCh37 15 43495332 43495332 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 40 62 0 ENST00000300215.3:c.1850G>A p.Arg617Lys p.R617K ENST00000300215 617 aGa/aAa 0 +EPHA10 UCSF GRCh37 1 38192817 38192817 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 24 15 0 ENST00000373048.4:c.1729C>T p.Leu577Phe p.L577F ENST00000373048 NM_001099439.1 577 Ctc/Ttc 0 +EPHA10 UCSF GRCh37 1 38186467 38186467 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 7 20 0 ENST00000373048.4:c.2196C>T p.Asp732= p.D732= ENST00000373048 NM_001099439.1 732 gaC/gaT 0 +EPHA6 UCSF GRCh37 3 96945231 96945231 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 68 123 0 ENST00000389672.5:c.1238C>T p.Ala413Val p.A413V ENST00000389672 NM_001080448.2 413 gCt/gTt 0 +EPM2AIP1 UCSF GRCh37 3 37033850 37033850 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 256 97 124 0 ENST00000322716.5:c.719G>A p.Arg240Lys p.R240K ENST00000322716 NM_014805.3 240 aGa/aAa 0 +EPN2 UCSF GRCh37 17 19232186 19232186 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 31 44 0 ENST00000314728.5:c.1310C>T p.Pro437Leu p.P437L ENST00000314728 NM_014964.4 437 cCc/cTc 0 +EPOR UCSF GRCh37 19 11493890 11493890 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 26 26 0 ENST00000222139.6:c.134G>A p.Arg45Gln p.R45Q ENST00000222139 NM_000121.3 45 cGg/cAg 0 +EPOR UCSF GRCh37 19 11492447 11492447 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 23 13 0 ENST00000222139.6:c.506C>T p.Pro169Leu p.P169L ENST00000222139 NM_000121.3 169 cCg/cTg 0 +EPS8L1 UCSF GRCh37 19 55597464 55597464 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 57 39 0 ENST00000201647.6:c.1554G>A p.Arg518= p.R518= ENST00000201647 NM_133180.2 518 cgG/cgA 0 +EPS8L3 UCSF GRCh37 1 110293937 110293937 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 10 29 0 ENST00000369805.3:c.1603G>A p.Val535Ile p.V535I ENST00000369805 NM_139053.2 535 Gtc/Atc 0 +ERBB2IP UCSF GRCh37 5 65350348 65350348 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 46 75 0 ENST00000506030.1:c.3202G>A p.Ala1068Thr p.A1068T ENST00000506030 1068 Gca/Aca 0 +ERBB4 UCSF GRCh37 2 212426739 212426739 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 49 71 0 ENST00000342788.4:c.2376C>T p.Ile792= p.I792= ENST00000342788 NM_005235.2 792 atC/atT 0 +ERC2 UCSF GRCh37 3 56330151 56330151 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 207 133 160 0 ENST00000288221.6:c.970G>A p.Asp324Asn p.D324N ENST00000288221 NM_015576.1 324 Gat/Aat 0 +ERCC6 UCSF GRCh37 10 50732465 50732465 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 52 100 0 ENST00000355832.5:c.1011G>A p.Lys337= p.K337= ENST00000355832 NM_000124.3 337 aaG/aaA 0 +ERF UCSF GRCh37 19 42752920 42752920 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 155 107 82 0 ENST00000222329.4:c.1344G>A p.Glu448= p.E448= ENST00000222329 NM_006494.2 448 gaG/gaA 0 +ERG UCSF GRCh37 21 39817432 39817432 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 23 39 0 ENST00000288319.7:c.131C>T p.Thr44Ile p.T44I ENST00000288319 NM_182918.3 44 aCt/aTt 0 +ERGIC3 UCSF GRCh37 20 34142816 34142816 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 49 62 0 ENST00000357394.4:c.702C>T p.Ile234= p.I234= ENST00000357394 NM_198398.1 234 atC/atT 0 +ERN1 UCSF GRCh37 17 62130161 62130161 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 34 68 0 ENST00000433197.3:c.2232C>T p.Ser744= p.S744= ENST00000433197 NM_001433.3 744 agC/agT 0 +ESCO1 UCSF GRCh37 18 19147941 19147941 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 39 103 0 ENST00000269214.5:c.1645G>A p.Gly549Ser p.G549S ENST00000269214 NM_052911.2 549 Ggt/Agt 0 +ESF1 UCSF GRCh37 20 13753186 13753186 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 40 63 0 ENST00000202816.1:c.1225C>T p.Pro409Ser p.P409S ENST00000202816 NM_001276380.1 409 Cct/Tct 0 +ESPL1 UCSF GRCh37 12 53677943 53677943 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 70 47 83 0 ENST00000257934.4:c.3179C>T p.Ser1060Phe p.S1060F ENST00000257934 NM_012291.4 1060 tCt/tTt 0 +ESPL1 UCSF GRCh37 12 53687255 53687255 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 15 31 0 ENST00000257934.4:c.6360G>A p.Arg2120= p.R2120= ENST00000257934 NM_012291.4 2120 cgG/cgA 0 +ESPNL UCSF GRCh37 2 239025622 239025622 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 19 26 0 ENST00000343063.3:c.934G>A p.Glu312Lys p.E312K ENST00000343063 NM_194312.2 312 Gag/Aag 0 +ESR2 UCSF GRCh37 14 64701863 64701863 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 55 9 27 0 ENST00000341099.4:c.1231T>G p.Tyr411Asp p.Y411D ENST00000341099 NM_001437.2 411 Tac/Gac 0 +ESR2 UCSF GRCh37 14 64701834 64701834 + synonymous_variant Silent SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 59 15 36 0 ENST00000341099.4:c.1260T>G p.Ala420= p.A420= ENST00000341099 NM_001437.2 420 gcT/gcG 0 +ESYT3 UCSF GRCh37 3 138189831 138189831 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 21 51 0 ENST00000389567.4:c.1703G>A p.Gly568Asp p.G568D ENST00000389567 NM_031913.3 568 gGc/gAc 0 +EXT2 UCSF GRCh37 11 44193294 44193294 + splice_donor_variant Splice_Site SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 28 59 109 0 ENST00000395673.3:c.1404+2T>C p.X468_splice ENST00000395673 NM_000401.3 0 +EZH2 UCSF GRCh37 7 148544360 148544360 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 278 87 169 0 ENST00000320356.2:c.31G>A p.Gly11Arg p.G11R ENST00000320356 NM_004456.4 11 Gga/Aga 0 +F2 UCSF GRCh37 11 46750944 46750944 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 14 26 36 0 ENST00000311907.5:c.1487G>A p.Gly496Glu p.G496E ENST00000311907 NM_000506.3 496 gGa/gAa 0 +F9 UCSF GRCh37 X 138619538 138619538 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 29 29 0 ENST00000218099.2:c.270G>A p.Gln90= p.Q90= ENST00000218099 NM_000133.3 90 caG/caA 0 +FA2H UCSF GRCh37 16 74750431 74750431 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 38 9 11 0 ENST00000219368.3:c.853T>C p.Tyr285His p.Y285H ENST00000219368 NM_024306.4 285 Tac/Cac 0 +FABP7 UCSF GRCh37 6 123104903 123104903 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 44 54 0 ENST00000368444.3:c.390G>A p.Glu130= p.E130= ENST00000368444 NM_001446.3 130 gaG/gaA 0 +FAF2 UCSF GRCh37 5 175919294 175919294 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 34 48 0 ENST00000261942.6:c.444G>A p.Gly148= p.G148= ENST00000261942 NM_014613.2 148 ggG/ggA 0 +FAM109A UCSF GRCh37 12 111801103 111801103 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 12 13 0 ENST00000361483.3:c.168G>A p.Gly56= p.G56= ENST00000361483 NM_001177996.1 56 ggG/ggA 0 +FAM109B UCSF GRCh37 22 42473561 42473561 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 76 45 0 ENST00000321753.3:c.264C>T p.Ala88= p.A88= ENST00000321753 NM_001002034.2 88 gcC/gcT 0 +FAM125A UCSF GRCh37 19 17534588 17534588 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 22 24 0 ENST00000317040.7:c.620C>T p.Ser207Phe p.S207F ENST00000317040 207 tCc/tTc 0 +FAM178A UCSF GRCh37 10 102676714 102676714 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 42 76 0 ENST00000370269.3:c.572G>A p.Gly191Asp p.G191D ENST00000370269 NM_001136123.1 191 gGc/gAc 0 +FAM179B UCSF GRCh37 14 45432024 45432024 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 69 63 0 ENST00000361577.3:c.400G>A p.Glu134Lys p.E134K ENST00000361577 NM_015091.2 134 Gaa/Aaa 0 +FAM186B UCSF GRCh37 12 49993278 49993278 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 17 31 0 ENST00000257894.2:c.2145C>T p.Ile715= p.I715= ENST00000257894 NM_032130.2 715 atC/atT 0 +FAM190A UCSF GRCh37 4 91229440 91229440 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 25 50 0 ENST00000509176.1:c.5G>A p.Gly2Glu p.G2E ENST00000509176 NM_001145065.1 2 gGg/gAg 0 +FAM198A UCSF GRCh37 3 43073791 43073791 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 28 23 0 ENST00000430121.2:c.36G>A p.Lys12= p.K12= ENST00000430121 NM_001129908.2 12 aaG/aaA 0 +FAM19A3 UCSF GRCh37 1 113266678 113266678 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 39 20 24 0 ENST00000369630.3:c.377C>T p.Ala126Val p.A126V ENST00000369630 126 gCc/gTc 0 +FAM208A UCSF GRCh37 3 56675640 56675640 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 57 105 0 ENST00000493960.2:c.2356G>A p.Asp786Asn p.D786N ENST00000493960 NM_001112736.1 786 Gat/Aat 0 +FAM208B UCSF GRCh37 10 5772723 5772723 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 134 85 124 0 ENST00000328090.5:c.761C>T p.Ser254Leu p.S254L ENST00000328090 NM_017782.4 254 tCa/tTa 0 +FAM20B UCSF GRCh37 1 179013332 179013332 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 23 42 0 ENST00000263733.4:c.350G>A p.Gly117Asp p.G117D ENST00000263733 NM_014864.3 117 gGc/gAc 0 +FAM46D UCSF GRCh37 X 79698982 79698982 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 51 104 0 ENST00000538312.1:c.944G>A p.Ser315Asn p.S315N ENST00000538312 NM_001170574.1 315 aGt/aAt 0 +FAM50B UCSF GRCh37 6 3850294 3850294 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 31 8 0 ENST00000380274.1:c.249G>A p.Glu83= p.E83= ENST00000380274 83 gaG/gaA 0 +FAM54B UCSF GRCh37 1 26156015 26156015 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 157 19 129 0 ENST00000374301.3:c.467C>T p.Thr156Met p.T156M ENST00000374301 NM_019557.5 156 aCg/aTg 0 +FAM65A UCSF GRCh37 16 67573757 67573757 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 278 97 114 0 ENST00000422602.2:c.429G>A p.Lys143= p.K143= ENST00000422602 NM_001193523.1 143 aaG/aaA 0 +FAM78A UCSF GRCh37 9 134136293 134136293 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 116 57 44 0 ENST00000372271.3:c.768G>A p.Lys256= p.K256= ENST00000372271 NM_033387.3 256 aaG/aaA 0 +FAM90A1 UCSF GRCh37 12 8375120 8375120 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 225 93 102 0 ENST00000538603.1:c.693C>T p.Ser231= p.S231= ENST00000538603 NM_018088.3 231 agC/agT 0 +FANCD2 UCSF GRCh37 3 10091058 10091058 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 218 35 174 0 ENST00000287647.3:c.1414G>A p.Glu472Lys p.E472K ENST00000287647 NM_033084.3 472 Gaa/Aaa 0 +FANCE UCSF GRCh37 6 35423814 35423814 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 24 26 0 ENST00000229769.2:c.539C>T p.Ser180Phe p.S180F ENST00000229769 NM_021922.2 180 tCc/tTc 0 +FAR2 UCSF GRCh37 12 29423433 29423433 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 13 48 0 ENST00000536681.3:c.51G>A p.Gly17= p.G17= ENST00000536681 NM_001271783.1 17 ggG/ggA 0 +FASLG UCSF GRCh37 1 172634901 172634901 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 54 97 0 ENST00000367721.2:c.591C>T p.Phe197= p.F197= ENST00000367721 NM_000639.1 197 ttC/ttT 0 +FAT3 UCSF GRCh37 11 92531204 92531204 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 212 121 202 0 ENST00000298047.6:c.5025C>T p.Asp1675= p.D1675= ENST00000298047 1675 gaC/gaT 0 +FAT4 UCSF GRCh37 4 126371035 126371035 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 22 73 0 ENST00000394329.3:c.8864C>T p.Ser2955Phe p.S2955F ENST00000394329 NM_024582.4 2955 tCt/tTt 0 +FBN1 UCSF GRCh37 15 48786449 48786449 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 31 50 0 ENST00000316623.5:c.2680C>T p.Pro894Ser p.P894S ENST00000316623 NM_000138.4 894 Ccc/Tcc 0 +FBN2 UCSF GRCh37 5 127680179 127680179 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 25 87 0 ENST00000508053.1:c.3241C>T p.Pro1081Ser p.P1081S ENST00000508053 1081 Cct/Tct 0 +FBN3 UCSF GRCh37 19 8160848 8160848 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 27 28 0 ENST00000600128.1:c.5656G>A p.Asp1886Asn p.D1886N ENST00000600128 1886 Gat/Aat 0 +FBXL6 UCSF GRCh37 8 145580259 145580259 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 49 25 0 ENST00000331890.5:c.993+1G>A p.X331_splice ENST00000331890 NM_012162.3 0 +FBXO30 UCSF GRCh37 6 146121445 146121445 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 41 66 0 ENST00000237281.4:c.2035G>A p.Val679Ile p.V679I ENST00000237281 NM_032145.4 679 Gta/Ata 0 +FBXO39 UCSF GRCh37 17 6690152 6690152 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 27 68 0 ENST00000321535.4:c.1077C>T p.His359= p.H359= ENST00000321535 NM_153230.2 359 caC/caT 0 +FBXO41 UCSF GRCh37 2 73493648 73493648 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 12 11 0 ENST00000521871.1:c.1068C>T p.Ala356= p.A356= ENST00000521871 356 gcC/gcT 0 +FBXO47 UCSF GRCh37 17 37099972 37099972 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 25 64 0 ENST00000378079.2:c.811G>A p.Glu271Lys p.E271K ENST00000378079 NM_001008777.2 271 Gaa/Aaa 0 +FBXO7 UCSF GRCh37 22 32891500 32891500 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 20 30 0 ENST00000266087.7:c.1165G>A p.Asp389Asn p.D389N ENST00000266087 NM_012179.3 389 Gac/Aac 0 +FCGBP UCSF GRCh37 19 40366336 40366336 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 35 24 0 ENST00000221347.6:c.13898G>A p.Gly4633Glu p.G4633E ENST00000221347 NM_003890.2 4633 gGa/gAa 0 +FCGBP UCSF GRCh37 19 40412068 40412068 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 19 18 0 ENST00000221347.6:c.3560C>T p.Ala1187Val p.A1187V ENST00000221347 NM_003890.2 1187 gCc/gTc 0 +FCGRT UCSF GRCh37 19 50017164 50017164 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 65 96 0 ENST00000221466.5:c.99C>T p.His33= p.H33= ENST00000221466 NM_001136019.2 33 caC/caT 0 +FCRL2 UCSF GRCh37 1 157740198 157740198 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 32 72 0 ENST00000361516.3:c.310+1G>A p.X104_splice ENST00000361516 NM_030764.3 0 +FDXACB1 UCSF GRCh37 11 111747557 111747557 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 75 106 0 ENST00000260257.4:c.508G>A p.Ala170Thr p.A170T ENST00000260257 NM_138378.2 170 Gca/Aca 0 +FERMT1 UCSF GRCh37 20 6078170 6078170 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 37 67 0 ENST00000217289.4:c.957+1G>A p.X319_splice ENST00000217289 NM_017671.4 0 +FEZF1 UCSF GRCh37 7 121942396 121942396 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 138 54 73 0 ENST00000442488.2:c.1083C>T p.Asn361= p.N361= ENST00000442488 NM_001160264.1 361 aaC/aaT 0 +FFAR2 UCSF GRCh37 19 35941013 35941013 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 49 61 0 ENST00000599180.2:c.397G>A p.Ala133Thr p.A133T ENST00000599180 133 Gcc/Acc 0 +FGD2 UCSF GRCh37 6 36995279 36995279 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 69 66 0 ENST00000274963.8:c.1680G>A p.Lys560= p.K560= ENST00000274963 NM_173558.3 560 aaG/aaA 0 +FGD4 UCSF GRCh37 12 32778605 32778605 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 45 21 64 0 ENST00000427716.2:c.1653A>G p.Lys551= p.K551= ENST00000427716 NM_139241.2 551 aaA/aaG 0 +FGFBP1 UCSF GRCh37 4 15937893 15937893 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 50 90 0 ENST00000382333.1:c.363C>T p.Arg121= p.R121= ENST00000382333 NM_005130.4 121 cgC/cgT 0 +FGFBP2 UCSF GRCh37 4 15964200 15964200 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 49 74 0 ENST00000259989.6:c.553C>T p.Pro185Ser p.P185S ENST00000259989 NM_031950.3 185 Cct/Tct 0 +FGFR2 UCSF GRCh37 10 123276956 123276956 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 36 58 0 ENST00000358487.5:c.961G>A p.Asp321Asn p.D321N ENST00000358487 NM_000141.4 321 Gac/Aac 0 +FHL3 UCSF GRCh37 1 38463171 38463171 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 35 39 0 ENST00000373016.3:c.749C>T p.Ser250Phe p.S250F ENST00000373016 NM_001243878.1 250 tCc/tTc 0 +FITM2 UCSF GRCh37 20 42935321 42935321 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 26 72 0 ENST00000396825.3:c.733G>A p.Gly245Arg p.G245R ENST00000396825 NM_001080472.1 245 Gga/Aga 0 +FLG2 UCSF GRCh37 1 152330054 152330054 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 23 39 0 ENST00000388718.5:c.208G>A p.Asp70Asn p.D70N ENST00000388718 NM_001014342.2 70 Gac/Aac 0 +FLNA UCSF GRCh37 X 153590825 153590825 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 75 41 0 ENST00000369850.3:c.2526G>A p.Gly842= p.G842= ENST00000369850 NM_001110556.1 842 ggG/ggA 0 +FLNC UCSF GRCh37 7 128487825 128487825 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 51 35 0 ENST00000325888.8:c.4363G>A p.Ala1455Thr p.A1455T ENST00000325888 NM_001458.4 1455 Gct/Act 0 +FLNC UCSF GRCh37 7 128494664 128494664 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 11 9 0 ENST00000325888.8:c.6925C>T p.Leu2309= p.L2309= ENST00000325888 NM_001458.4 2309 Ctg/Ttg 0 +FLNC UCSF GRCh37 7 128490857 128490857 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 35 50 0 ENST00000325888.8:c.5399G>A p.Gly1800Glu p.G1800E ENST00000325888 NM_001458.4 1800 gGa/gAa 0 +FLOT2 UCSF GRCh37 17 27208323 27208323 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 44 69 0 ENST00000394908.4:c.985G>A p.Val329Ile p.V329I ENST00000394908 NM_004475.2 329 Gtc/Atc 0 +FLRT2 UCSF GRCh37 14 86089009 86089009 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 39 81 0 ENST00000330753.4:c.1151C>T p.Pro384Leu p.P384L ENST00000330753 NM_013231.4 384 cCc/cTc 0 +FMN1 UCSF GRCh37 15 33358853 33358853 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 47 126 0 ENST00000334528.9:c.1233G>A p.Arg411= p.R411= ENST00000334528 NM_001103184.3 411 cgG/cgA 0 +FMNL2 UCSF GRCh37 2 153468012 153468012 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 106 69 98 0 ENST00000288670.9:c.955G>A p.Ala319Thr p.A319T ENST00000288670 NM_052905.3 319 Gct/Act 0 +FOLH1B UCSF GRCh37 11 89429802 89429802 + splice_region_variant,non_coding_transcript_exon_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 17 34 0 ENST00000525540.1:n.1574C>T p.X525_splice ENST00000525540 0 +FOXA3 UCSF GRCh37 19 46375379 46375379 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 31 57 0 ENST00000302177.2:c.116C>T p.Ser39Phe p.S39F ENST00000302177 NM_004497.2 39 tCc/tTc 0 +FOXD4 UCSF GRCh37 9 116871 116871 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 31 38 0 ENST00000382500.2:c.1249G>A p.Glu417Lys p.E417K ENST00000382500 NM_207305.4 417 Gag/Aag 0 +FOXF1 UCSF GRCh37 16 86544368 86544368 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 136 55 35 0 ENST00000262426.4:c.193C>T p.Pro65Ser p.P65S ENST00000262426 NM_001451.2 65 Ccc/Tcc 0 +FOXM1 UCSF GRCh37 12 2981341 2981341 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 120 85 140 0 ENST00000342628.2:c.575C>T p.Ser192Phe p.S192F ENST00000342628 NM_202002.2 192 tCt/tTt 0 +FOXR1 UCSF GRCh37 11 118851225 118851225 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 38 71 0 ENST00000317011.3:c.637G>A p.Ala213Thr p.A213T ENST00000317011 NM_181721.2 213 Gcc/Acc 0 +FOXRED2 UCSF GRCh37 22 36894137 36894137 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 30 25 0 ENST00000397224.4:c.1283C>T p.Pro428Leu p.P428L ENST00000397224 NM_001102371.1 428 cCc/cTc 0 +FRAS1 UCSF GRCh37 4 79432566 79432566 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 84 138 0 ENST00000264895.6:c.9919C>T p.Pro3307Ser p.P3307S ENST00000264895 NM_025074.6 3307 Cca/Tca 0 +FRAS1 UCSF GRCh37 4 79229230 79229230 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 69 142 0 ENST00000264895.6:c.1545G>A p.Glu515= p.E515= ENST00000264895 NM_025074.6 515 gaG/gaA 0 +FREM1 UCSF GRCh37 9 14770618 14770618 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 52 74 0 ENST00000422223.2:c.5044G>A p.Glu1682Lys p.E1682K ENST00000422223 NM_144966.5 1682 Gag/Aag 0 +FREM2 UCSF GRCh37 13 39263675 39263675 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 39 68 0 ENST00000280481.7:c.2194G>A p.Asp732Asn p.D732N ENST00000280481 NM_207361.4 732 Gac/Aac 0 +FRMD3 UCSF GRCh37 9 85863162 85863162 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 58 112 0 ENST00000304195.3:c.1465G>A p.Asp489Asn p.D489N ENST00000304195 NM_001244960.1 489 Gat/Aat 0 +FRMD6 UCSF GRCh37 14 52194727 52194727 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 20 31 0 ENST00000344768.5:c.1849G>A p.Val617Ile p.V617I ENST00000344768 617 Gtt/Att 0 +FRMPD1 UCSF GRCh37 9 37746123 37746123 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 82 72 0 ENST00000539465.1:c.4094C>T p.Pro1365Leu p.P1365L ENST00000539465 1365 cCc/cTc 0 +FRMPD1 UCSF GRCh37 9 37735548 37735548 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 36 88 0 ENST00000539465.1:c.1219-1G>A p.X407_splice ENST00000539465 0 +FRY UCSF GRCh37 13 32653159 32653159 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 130 80 110 0 ENST00000380250.3:c.259G>A p.Ala87Thr p.A87T ENST00000380250 NM_023037.2 87 Gca/Aca 0 +FRY UCSF GRCh37 13 32805425 32805425 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 63 86 0 ENST00000380250.3:c.5515G>A p.Asp1839Asn p.D1839N ENST00000380250 NM_023037.2 1839 Gat/Aat 0 +FRY UCSF GRCh37 13 32868530 32868530 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 37 64 0 ENST00000380250.3:c.8606G>A p.Ser2869Asn p.S2869N ENST00000380250 NM_023037.2 2869 aGt/aAt 0 +FRY UCSF GRCh37 13 32776558 32776558 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 64 68 0 ENST00000380250.3:c.3912C>T p.Leu1304= p.L1304= ENST00000380250 NM_023037.2 1304 ctC/ctT 0 +FSCB UCSF GRCh37 14 44975886 44975886 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 126 87 201 0 ENST00000340446.4:c.305G>A p.Arg102Lys p.R102K ENST00000340446 NM_032135.3 102 aGa/aAa 0 +FSCB UCSF GRCh37 14 44974999 44974999 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 39 73 0 ENST00000340446.4:c.1192C>T p.Pro398Ser p.P398S ENST00000340446 NM_032135.3 398 Cct/Tct 0 +FSCN3 UCSF GRCh37 7 127240402 127240402 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 15 49 0 ENST00000265825.5:c.1446C>T p.Thr482= p.T482= ENST00000265825 NM_020369.2 482 acC/acT 0 +FSD1 UCSF GRCh37 19 4318408 4318408 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 22 24 0 ENST00000221856.6:c.865G>A p.Glu289Lys p.E289K ENST00000221856 NM_024333.2 289 Gag/Aag 0 +FSIP1 UCSF GRCh37 15 40005681 40005681 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 72 129 0 ENST00000350221.3:c.1152G>A p.Glu384= p.E384= ENST00000350221 NM_152597.4 384 gaG/gaA 0 +FSIP2 UCSF GRCh37 2 186656884 186656884 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 159 100 165 0 ENST00000343098.5:c.5288C>T p.Pro1763Leu p.P1763L ENST00000343098 NM_173651.2 1763 cCt/cTt 0 +FSIP2 UCSF GRCh37 2 186665992 186665992 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 54 85 0 ENST00000343098.5:c.12226C>T p.Leu4076Phe p.L4076F ENST00000343098 NM_173651.2 4076 Ctc/Ttc 0 +FSIP2 UCSF GRCh37 2 186657540 186657540 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 40 85 0 ENST00000343098.5:c.5944G>A p.Ala1982Thr p.A1982T ENST00000343098 NM_173651.2 1982 Gct/Act 0 +FSIP2 UCSF GRCh37 2 186667048 186667048 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 36 78 0 ENST00000343098.5:c.13282G>A p.Val4428Ile p.V4428I ENST00000343098 NM_173651.2 4428 Gta/Ata 0 +FSTL4 UCSF GRCh37 5 132560877 132560877 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 31 80 0 ENST00000265342.7:c.1277C>T p.Ser426Phe p.S426F ENST00000265342 NM_015082.1 426 tCc/tTc 0 +FUK UCSF GRCh37 16 70497664 70497664 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 10 15 0 ENST00000288078.6:c.221G>A p.Arg74Gln p.R74Q ENST00000288078 NM_145059.2 74 cGg/cAg 0 +FUT2 UCSF GRCh37 19 49206791 49206791 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 66 40 0 ENST00000425340.2:c.578G>A p.Gly193Asp p.G193D ENST00000425340 NM_001097638.2 193 gGc/gAc 0 +FUT6 UCSF GRCh37 19 5832069 5832069 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 46 42 0 ENST00000318336.4:c.510G>A p.Trp170Ter p.W170* ENST00000318336 NM_000150.2 170 tgG/tgA 0 +FYB UCSF GRCh37 5 39202562 39202562 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 155 81 171 1 ENST00000540520.1:c.531G>A p.Lys177= p.K177= ENST00000540520 NM_001243093.1 177 aaG/aaA 0 +FYCO1 UCSF GRCh37 3 46009818 46009818 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 168 45 51 0 ENST00000296137.2:c.1008C>T p.Ala336= p.A336= ENST00000296137 NM_024513.3 336 gcC/gcT 0 +FYCO1 UCSF GRCh37 3 46009686 46009686 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 287 98 172 0 ENST00000296137.2:c.1140T>C p.Asp380= p.D380= ENST00000296137 NM_024513.3 380 gaT/gaC 0 +FZD10 UCSF GRCh37 12 130647932 130647932 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 208 49 50 0 ENST00000229030.4:c.445G>A p.Glu149Lys p.E149K ENST00000229030 149 Gag/Aag 0 +FZD10 UCSF GRCh37 12 130649027 130649027 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 30 46 0 ENST00000229030.4:c.1540G>A p.Val514Met p.V514M ENST00000229030 514 Gtg/Atg 0 +GABBR1 UCSF GRCh37 6 29574681 29574681 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 38 69 0 ENST00000377034.4:c.2210C>T p.Thr737Ile p.T737I ENST00000377034 NM_001470.2 737 aCc/aTc 0 +GABBR2 UCSF GRCh37 9 101235433 101235433 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 20 36 0 ENST00000259455.2:c.994G>A p.Gly332Arg p.G332R ENST00000259455 NM_005458.7 332 Gga/Aga 0 +GABRB1 UCSF GRCh37 4 47034018 47034018 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 139 79 93 0 ENST00000295454.3:c.168C>T p.Phe56= p.F56= ENST00000295454 NM_000812.3 56 ttC/ttT 0 +GAGE2D UCSF GRCh37 X 49208299 49208313 + protein_altering_variant In_Frame_Ins INS CGGCCTAGACCAAGA CGGCCTAGACCAAGA TATTGGCCTAGACCAAGG NOVEL P05_Rec Untested WXS Illumina HiSeq 9 0 ENST00000404720.2:c.28_42delinsTATTGGCCTAGACCAAGG p.Arg10delinsTyrTrp p.R10delinsYW ENST00000404720 NM_001098407.1 10 CGGCCTAGACCAAGA/TATTGGCCTAGACCAAGG 0 +GALNS UCSF GRCh37 16 88889032 88889032 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 16 18 0 ENST00000268695.5:c.1329C>T p.His443= p.H443= ENST00000268695 NM_000512.4 443 caC/caT 0 +GALNTL5 UCSF GRCh37 7 151705015 151705015 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 127 30 100 0 ENST00000392800.2:c.1012G>A p.Glu338Lys p.E338K ENST00000392800 NM_145292.3 338 Gaa/Aaa 0 +GAPVD1 UCSF GRCh37 9 128099780 128099780 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 22 50 0 ENST00000394105.2:c.2868C>T p.Leu956= p.L956= ENST00000394105 NM_015635.2 956 ctC/ctT 0 +GARNL3 UCSF GRCh37 9 130127616 130127616 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 225 64 123 0 ENST00000373387.4:c.2132G>A p.Gly711Glu p.G711E ENST00000373387 NM_032293.4 711 gGa/gAa 0 +GAS2L2 UCSF GRCh37 17 34072427 34072427 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 71 72 0 ENST00000254466.6:c.2089G>A p.Gly697Arg p.G697R ENST00000254466 NM_139285.3 697 Gga/Aga 0 +GAS2L3 UCSF GRCh37 12 100994246 100994246 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 35 95 0 ENST00000539410.1:c.105C>T p.Tyr35= p.Y35= ENST00000539410 35 taC/taT 0 +GATAD1 UCSF GRCh37 7 92083940 92083940 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 149 49 72 0 ENST00000287957.3:c.560G>A p.Trp187Ter p.W187* ENST00000287957 NM_021167.4 187 tGg/tAg 0 +GCAT UCSF GRCh37 22 38205992 38205992 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 43 61 0 ENST00000323205.6:c.233C>T p.Pro78Leu p.P78L ENST00000323205 NM_001171690.1 78 cCc/cTc 0 +GCAT UCSF GRCh37 22 38205980 38205980 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 34 59 0 ENST00000323205.6:c.221G>A p.Gly74Asp p.G74D ENST00000323205 NM_001171690.1 74 gGc/gAc 0 +GCNT3 UCSF GRCh37 15 59911202 59911202 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.004,1000g2011may_all_0.01089,snp132_rs35655456 P05_Rec Untested WXS Illumina HiSeq 192 90 169 0 ENST00000396065.1:c.765G>A p.Glu255= p.E255= ENST00000396065 NM_004751.2 255 gaG/gaA 0 +GCNT7 UCSF GRCh37 20 55070281 55070281 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 13 40 0 ENST00000243913.4:c.677G>A p.Gly226Glu p.G226E ENST00000243913 NM_080615.1 226 gGa/gAa 0 +GFI1B UCSF GRCh37 9 135862166 135862166 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 8 10 0 ENST00000339463.3:c.100+1G>A p.X34_splice ENST00000339463 0 +GFRA1 UCSF GRCh37 10 117823939 117823939 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 31 52 0 ENST00000355422.6:c.1368C>T p.Ser456= p.S456= ENST00000355422 NM_005264.4 456 tcC/tcT 0 +GGT1 UCSF GRCh37 22 25007180 25007180 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 7 24 1 ENST00000400382.1:c.132C>T p.Ala44= p.A44= ENST00000400382 NM_001288833.1 44 gcC/gcT 0 +GHRHR UCSF GRCh37 7 31008476 31008476 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 21 41 0 ENST00000326139.2:c.85G>T p.Asp29Tyr p.D29Y ENST00000326139 NM_000823.3 29 Gac/Tac 0 +GIMAP2 UCSF GRCh37 7 150389551 150389551 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 29 94 0 ENST00000223293.5:c.177G>A p.Lys59= p.K59= ENST00000223293 NM_015660.2 59 aaG/aaA 0 +GIMAP8 UCSF GRCh37 7 150163967 150163967 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 160 69 115 0 ENST00000307271.3:c.181G>A p.Val61Ile p.V61I ENST00000307271 NM_175571.2 61 Gtt/Att 0 +GIMAP8 UCSF GRCh37 7 150171237 150171237 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 119 27 59 0 ENST00000307271.3:c.820C>T p.Gln274Ter p.Q274* ENST00000307271 NM_175571.2 274 Cag/Tag 0 +GIT1 UCSF GRCh37 17 27904199 27904199 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 175 106 89 0 ENST00000394869.3:c.1075G>A p.Glu359Lys p.E359K ENST00000394869 NM_001085454.1 359 Gag/Aag 0 +GJB6 UCSF GRCh37 13 20797371 20797371 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 28 35 0 ENST00000356192.6:c.249C>T p.Phe83= p.F83= ENST00000356192 NM_001110219.2 83 ttC/ttT 0 +GJB7 UCSF GRCh37 6 87994398 87994398 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 46 90 0 ENST00000525899.1:c.233C>T p.Ala78Val p.A78V ENST00000525899 NM_198568.2 78 gCc/gTc 0 +GLDC UCSF GRCh37 9 6592855 6592855 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 32 73 0 ENST00000321612.6:c.1397G>A p.Gly466Asp p.G466D ENST00000321612 NM_000170.2 466 gGc/gAc 0 +GLDC UCSF GRCh37 9 6587248 6587248 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 29 68 0 ENST00000321612.6:c.1743C>T p.Pro581= p.P581= ENST00000321612 NM_000170.2 581 ccC/ccT 0 +GLI3 UCSF GRCh37 7 42187981 42187981 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 12 43 0 ENST00000395925.3:c.211G>A p.Val71Ile p.V71I ENST00000395925 NM_000168.5 71 Gtc/Atc 0 +GLI3 UCSF GRCh37 7 42079724 42079724 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 39 54 0 ENST00000395925.3:c.941C>T p.Pro314Leu p.P314L ENST00000395925 NM_000168.5 314 cCc/cTc 0 +GLIS3 UCSF GRCh37 9 3937133 3937133 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 59 72 0 ENST00000381971.3:c.1767G>A p.Arg589= p.R589= ENST00000381971 NM_001042413.1 589 cgG/cgA 0 +GLRA4 UCSF GRCh37 X 102977152 102977152 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 122 131 0 ENST00000372617.4:c.646G>A p.Gly216Arg p.G216R ENST00000372617 NM_001024452.2 216 Ggg/Agg 0 +GLT8D2 UCSF GRCh37 12 104387238 104387238 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 9 19 0 ENST00000360814.4:c.812C>T p.Ser271Phe p.S271F ENST00000360814 NM_031302.3 271 tCc/tTc 0 +GLUD1 UCSF GRCh37 10 88818930 88818930 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 99 132 0 ENST00000277865.4:c.1379G>A p.Arg460Lys p.R460K ENST00000277865 NM_005271.3 460 aGg/aAg 0 +GLYAT UCSF GRCh37 11 58491934 58491934 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 50 80 0 ENST00000344743.3:c.36G>A p.Gln12= p.Q12= ENST00000344743 NM_201648.2 12 caG/caA 0 +GMEB1 UCSF GRCh37 1 29041273 29041273 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 35 64 0 ENST00000294409.2:c.1710C>T p.Val570= p.V570= ENST00000294409 NM_006582.3 570 gtC/gtT 0 +GMEB2 UCSF GRCh37 20 62221730 62221730 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 16 8 0 ENST00000266068.1:c.1305C>T p.Ala435= p.A435= ENST00000266068 435 gcC/gcT 0 +GMPR UCSF GRCh37 6 16254852 16254852 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 57 125 1 ENST00000259727.4:c.351G>A p.Leu117= p.L117= ENST00000259727 NM_006877.3 117 ctG/ctA 0 +GNAI1 UCSF GRCh37 7 79818509 79818509 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 19 51 0 ENST00000351004.3:c.265G>A p.Gly89Arg p.G89R ENST00000351004 NM_002069.5 89 Ggg/Agg 0 +GNAI2 UCSF GRCh37 3 50294993 50294993 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 14 46 0 ENST00000313601.6:c.939G>A p.Lys313= p.K313= ENST00000313601 NM_002070.2 313 aaG/aaA 0 +GNG4 UCSF GRCh37 1 235715517 235715517 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 49 88 0 ENST00000391854.2:c.120C>T p.Asp40= p.D40= ENST00000391854 NM_001098722.1 40 gaC/gaT 0 +GNPAT UCSF GRCh37 1 231403448 231403448 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 57 101 0 ENST00000366647.4:c.1078G>A p.Glu360Lys p.E360K ENST00000366647 NM_014236.3 360 Gag/Aag 0 +GON4L UCSF GRCh37 1 155774791 155774791 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 51 118 0 ENST00000437809.1:c.1594G>A p.Asp532Asn p.D532N ENST00000437809 532 Gac/Aac 0 +GORASP1 UCSF GRCh37 3 39141805 39141805 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 20 27 0 ENST00000319283.3:c.756C>T p.Asp252= p.D252= ENST00000319283 NM_031899.3 252 gaC/gaT 0 +GPC3 UCSF GRCh37 X 132888089 132888089 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 92 157 0 ENST00000394299.2:c.452A>T p.Asp151Val p.D151V ENST00000394299 NM_001164617.1 151 gAt/gTt 0 +GPHN UCSF GRCh37 14 67626206 67626206 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 51 60 0 ENST00000478722.1:c.1910+1G>A p.X637_splice ENST00000478722 NM_020806.4 0 +GPM6B UCSF GRCh37 X 13825868 13825868 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 45 89 0 ENST00000316715.4:c.82G>A p.Glu28Lys p.E28K ENST00000316715 NM_001001995.1 28 Gaa/Aaa 0 +GPR124 UCSF GRCh37 8 37690588 37690588 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 53 50 0 ENST00000412232.2:c.1158C>T p.Thr386= p.T386= ENST00000412232 NM_032777.9 386 acC/acT 0 +GPR146 UCSF GRCh37 7 1097986 1097986 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 35 55 0 ENST00000397095.1:c.835G>A p.Asp279Asn p.D279N ENST00000397095 279 Gat/Aat 0 +GPR155 UCSF GRCh37 2 175335147 175335147 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 17 50 0 ENST00000392552.2:c.997G>A p.Ala333Thr p.A333T ENST00000392552 NM_152529.6 333 Gca/Aca 0 +GPR179 UCSF GRCh37 17 36483358 36483358 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 53 99 0 ENST00000342292.4:c.6094G>A p.Val2032Met p.V2032M ENST00000342292 NM_001004334.2 2032 Gtg/Atg 0 +GPR179 UCSF GRCh37 17 36499107 36499107 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 42 61 0 ENST00000342292.4:c.566C>T p.Pro189Leu p.P189L ENST00000342292 NM_001004334.2 189 cCt/cTt 0 +GPR20 UCSF GRCh37 8 142367957 142367957 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 21 12 0 ENST00000377741.3:c.67G>A p.Val23Met p.V23M ENST00000377741 NM_005293.2 23 Gtg/Atg 0 +GPR20 UCSF GRCh37 8 142367775 142367775 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 62 28 0 ENST00000377741.3:c.249G>A p.Arg83= p.R83= ENST00000377741 NM_005293.2 83 cgG/cgA 0 +GPR3 UCSF GRCh37 1 27720670 27720670 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 134 81 58 0 ENST00000374024.3:c.368G>A p.Ser123Asn p.S123N ENST00000374024 NM_005281.3 123 aGc/aAc 0 +GPR97 UCSF GRCh37 16 57712211 57712211 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 36 46 0 ENST00000333493.4:c.475C>T p.Pro159Ser p.P159S ENST00000333493 NM_170776.4 159 Cca/Tca 0 +GPR98 UCSF GRCh37 5 90368287 90368287 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 68 129 0 ENST00000405460.2:c.18176C>T p.Ala6059Val p.A6059V ENST00000405460 NM_032119.3 6059 gCt/gTt 0 +GPRC5B UCSF GRCh37 16 19883984 19883984 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 46 28 0 ENST00000300571.2:c.184G>A p.Val62Met p.V62M ENST00000300571 NM_016235.1 62 Gtg/Atg 0 +GRB7 UCSF GRCh37 17 37898594 37898594 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 116 77 102 0 ENST00000445327.2:c.109C>T p.Pro37Ser p.P37S ENST00000445327 NM_001242442.1 37 Ccg/Tcg 0 +GRHL3 UCSF GRCh37 1 24658026 24658026 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 49 73 0 ENST00000350501.5:c.128C>T p.Ala43Val p.A43V ENST00000350501 NM_198174.2 43 gCc/gTc 0 +GRID2 UCSF GRCh37 4 94436455 94436455 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 53 72 0 ENST00000282020.4:c.2086C>T p.Leu696= p.L696= ENST00000282020 NM_001510.2 696 Ctg/Ttg 0 +GRIN2A UCSF GRCh37 16 9857804 9857804 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 161 79 146 0 ENST00000330684.3:c.3597G>A p.Pro1199= p.P1199= ENST00000330684 NM_001134407.1 1199 ccG/ccA 0 +GRIN2A UCSF GRCh37 16 10273879 10273879 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 45 27 0 ENST00000330684.3:c.390C>T p.Gly130= p.G130= ENST00000330684 NM_001134407.1 130 ggC/ggT 0 +GRIN3B UCSF GRCh37 19 1005407 1005407 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 66 35 0 ENST00000234389.3:c.1907C>T p.Thr636Met p.T636M ENST00000234389 NM_138690.1 636 aCg/aTg 0 +GRK1 UCSF GRCh37 13 114322040 114322040 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 64 67 0 ENST00000335678.6:c.339G>A p.Gln113= p.Q113= ENST00000335678 NM_002929.2 113 caG/caA 0 +GRM1 UCSF GRCh37 6 146351336 146351336 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 31 65 0 ENST00000361719.2:c.683C>T p.Ser228Phe p.S228F ENST00000361719 228 tCt/tTt 0 +GRM1 UCSF GRCh37 6 146673547 146673547 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 52 105 0 ENST00000361719.2:c.1348C>T p.Leu450= p.L450= ENST00000361719 450 Ctg/Ttg 0 +GRM2 UCSF GRCh37 3 51750123 51750123 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 15 31 0 ENST00000395052.3:c.2334C>T p.Pro778= p.P778= ENST00000395052 NM_000839.3 778 ccC/ccT 0 +GSTA3 UCSF GRCh37 6 52764848 52764848 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 61 149 0 ENST00000211122.3:c.298G>A p.Ala100Thr p.A100T ENST00000211122 NM_000847.4 100 Gca/Aca 0 +GTF2A1L UCSF GRCh37 2 48874040 48874040 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 20 37 64 0 ENST00000394754.1:c.2949C>T p.Leu983= p.L983= ENST00000394754 NM_172311.2 983 ctC/ctT 0 +GTF2H4 UCSF GRCh37 6 30880904 30880904 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 27 23 0 ENST00000259895.4:c.1107G>A p.Arg369= p.R369= ENST00000259895 NM_001517.4 369 agG/agA 0 +GTF2IRD1 UCSF GRCh37 7 73927195 73927195 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 29 30 0 ENST00000455841.2:c.159C>T p.Ala53= p.A53= ENST00000455841 NM_001199207.1 53 gcC/gcT 0 +GTF3C1 UCSF GRCh37 16 27506726 27506726 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 15 19 0 ENST00000356183.4:c.2438G>A p.Gly813Glu p.G813E ENST00000356183 NM_001520.3 813 gGg/gAg 0 +GTSE1 UCSF GRCh37 22 46704798 46704798 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 46 46 0 ENST00000454366.1:c.720G>A p.Ala240= p.A240= ENST00000454366 NM_016426.6 240 gcG/gcA 0 +GUCY1A2 UCSF GRCh37 11 106558395 106558395 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 142 105 117 0 ENST00000282249.2:c.2172C>T p.Ile724= p.I724= ENST00000282249 NM_001256424.1 724 atC/atT 0 +GUF1 UCSF GRCh37 4 44688578 44688578 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 56 90 0 ENST00000281543.5:c.786C>T p.Thr262= p.T262= ENST00000281543 NM_021927.2 262 acC/acT 0 +GZMH UCSF GRCh37 14 25077492 25077492 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 33 74 0 ENST00000216338.4:c.182C>T p.Thr61Ile p.T61I ENST00000216338 NM_033423.4 61 aCa/aTa 0 +H1FNT UCSF GRCh37 12 48723752 48723752 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 9 13 0 ENST00000335017.1:c.678G>A p.Thr226= p.T226= ENST00000335017 NM_181788.1 226 acG/acA 0 +H6PD UCSF GRCh37 1 9324739 9324739 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 49 17 0 ENST00000377403.2:c.2187G>A p.Met729Ile p.M729I ENST00000377403 NM_004285.3 729 atG/atA 0 +HACE1 UCSF GRCh37 6 105225138 105225138 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 48 73 0 ENST00000262903.4:c.1621G>A p.Asp541Asn p.D541N ENST00000262903 NM_020771.3 541 Gat/Aat 0 +HACE1 UCSF GRCh37 6 105232911 105232911 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 46 86 0 ENST00000262903.4:c.1358G>A p.Ser453Asn p.S453N ENST00000262903 NM_020771.3 453 aGt/aAt 0 +HADHA UCSF GRCh37 2 26415196 26415196 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 66 109 0 ENST00000380649.3:c.1983G>A p.Leu661= p.L661= ENST00000380649 NM_000182.4 661 ctG/ctA 0 +HAO2 UCSF GRCh37 1 119927582 119927582 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 39 90 0 ENST00000325945.3:c.467C>T p.Thr156Ile p.T156I ENST00000325945 NM_016527.2 156 aCt/aTt 0 +HCRTR1 UCSF GRCh37 1 32084911 32084911 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 165 78 70 0 ENST00000403528.2:c.118C>T p.Leu40= p.L40= ENST00000403528 NM_001525.2 40 Ctg/Ttg 0 +HDAC4 UCSF GRCh37 2 240029877 240029877 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 12 12 0 ENST00000345617.3:c.1966C>T p.Leu656Phe p.L656F ENST00000345617 NM_006037.3 656 Ctc/Ttc 0 +HDAC6 UCSF GRCh37 X 48666703 48666703 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 7 20 0 ENST00000334136.5:c.776G>A p.Gly259Glu p.G259E ENST00000334136 259 gGa/gAa 0 +HDC UCSF GRCh37 15 50535041 50535041 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 39 46 43 0 ENST00000267845.3:c.1405G>C p.Asp469His p.D469H ENST00000267845 NM_002112.3 469 Gat/Cat 0 +HDC UCSF GRCh37 15 50546769 50546769 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 25 46 0 ENST00000267845.3:c.534G>A p.Glu178= p.E178= ENST00000267845 NM_002112.3 178 gaG/gaA 0 +HEATR1 UCSF GRCh37 1 236761195 236761195 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 37 80 0 ENST00000366582.3:c.586G>A p.Val196Met p.V196M ENST00000366582 NM_018072.5 196 Gtg/Atg 0 +HEATR3 UCSF GRCh37 16 50112689 50112689 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 26 51 0 ENST00000299192.7:c.801G>A p.Lys267= p.K267= ENST00000299192 NM_182922.2 267 aaG/aaA 0 +HEATR4 UCSF GRCh37 14 73987712 73987712 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 44 118 0 ENST00000553558.1:c.913G>A p.Val305Ile p.V305I ENST00000553558 NM_001220484.1 305 Gtt/Att 0 +HECTD1 UCSF GRCh37 14 31575929 31575929 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 43 62 0 ENST00000399332.1:c.7149G>A p.Glu2383= p.E2383= ENST00000399332 NM_015382.2 2383 gaG/gaA 0 +HELQ UCSF GRCh37 4 84342833 84342833 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 30 43 0 ENST00000295488.3:c.2832G>A p.Leu944= p.L944= ENST00000295488 NM_133636.2 944 ttG/ttA 0 +HEPH UCSF GRCh37 X 65483531 65483531 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 32 85 0 ENST00000519389.1:c.3406+1G>A p.X1136_splice ENST00000519389 0 +HEPHL1 UCSF GRCh37 11 93806331 93806331 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 95 146 0 ENST00000315765.9:c.1372+1G>A p.X458_splice ENST00000315765 NM_001098672.1 0 +HERC2 UCSF GRCh37 15 28408403 28408403 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 48 57 0 ENST00000261609.7:c.10583G>A p.Gly3528Asp p.G3528D ENST00000261609 NM_004667.5 3528 gGt/gAt 0 +HERC2 UCSF GRCh37 15 28517390 28517390 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 15 48 0 ENST00000261609.7:c.1054G>A p.Asp352Asn p.D352N ENST00000261609 NM_004667.5 352 Gat/Aat 0 +HESX1 UCSF GRCh37 3 57232915 57232915 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 254 142 176 0 ENST00000295934.3:c.223G>A p.Val75Met p.V75M ENST00000295934 NM_003865.2 75 Gtg/Atg 0 +HEXDC UCSF GRCh37 17 80395092 80395092 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 141 79 40 0 ENST00000337014.6:c.752C>T p.Ala251Val p.A251V ENST00000337014 NM_173620.2 251 gCa/gTa 0 +HFM1 UCSF GRCh37 1 91844621 91844621 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 28 47 0 ENST00000370425.3:c.1157C>T p.Pro386Leu p.P386L ENST00000370425 NM_001017975.3 386 cCa/cTa 0 +HIAT1 UCSF GRCh37 1 100535242 100535242 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 36 72 0 ENST00000370152.3:c.891+1G>A p.X297_splice ENST00000370152 NM_033055.2 0 +HIF1A UCSF GRCh37 14 62204870 62204870 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 55 66 0 ENST00000539097.1:c.1387C>T p.Pro463Ser p.P463S ENST00000539097 NM_001243084.1 463 Ccc/Tcc 0 +HIP1 UCSF GRCh37 7 75211432 75211432 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 5 13 0 ENST00000336926.6:c.501C>T p.Asp167= p.D167= ENST00000336926 NM_005338.6 167 gaC/gaT 0 +HIST1H2AE UCSF GRCh37 6 26217364 26217364 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 41 81 0 ENST00000303910.2:c.162G>A p.Ala54= p.A54= ENST00000303910 NM_021052.2 54 gcG/gcA 0 +HIST1H4L UCSF GRCh37 6 27841178 27841178 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 68 58 0 ENST00000355981.2:c.111C>T p.Arg37= p.R37= ENST00000355981 NM_003546.2 37 cgC/cgT 0 +HIST3H2BB UCSF GRCh37 1 228645954 228645954 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 203 113 88 0 ENST00000369160.2:c.124G>A p.Val42Met p.V42M ENST00000369160 NM_175055.2 42 Gtg/Atg 0 +HIVEP1 UCSF GRCh37 6 12164042 12164042 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 51 83 0 ENST00000379388.2:c.7505C>T p.Ala2502Val p.A2502V ENST00000379388 NM_002114.2 2502 gCc/gTc 0 +HK3 UCSF GRCh37 5 176315739 176315739 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 33 49 0 ENST00000292432.5:c.1041C>T p.Ile347= p.I347= ENST00000292432 NM_002115.2 347 atC/atT 0 +HKR1 UCSF GRCh37 19 37854105 37854105 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 41 92 0 ENST00000324411.4:c.1408G>A p.Val470Ile p.V470I ENST00000324411 NM_181786.2 470 Gtc/Atc 0 +HLA-DPB1 UCSF GRCh37 6 33053574 33053574 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 19 56 0 ENST00000418931.2:c.665C>T p.Ala222Val p.A222V ENST00000418931 NM_002121.5 222 gCc/gTc 0 +HLA-F UCSF GRCh37 6 29692880 29692880 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 61 34 62 0 ENST00000259951.7:c.683G>C p.Gly228Ala p.G228A ENST00000259951 NM_001098479.1 228 gGc/gCc 0 +HMCN1 UCSF GRCh37 1 186039866 186039866 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 42 97 0 ENST00000271588.4:c.8116C>T p.Leu2706Phe p.L2706F ENST00000271588 NM_031935.2 2706 Ctc/Ttc 0 +HMCN1 UCSF GRCh37 1 186007969 186007969 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 68 47 83 0 ENST00000271588.4:c.5860T>C p.Trp1954Arg p.W1954R ENST00000271588 NM_031935.2 1954 Tgg/Cgg 0 +HMG20A UCSF GRCh37 15 77771634 77771634 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 29 86 0 ENST00000381714.3:c.1021G>A p.Val341Ile p.V341I ENST00000381714 NM_018200.2 341 Gtt/Att 0 +HMGXB4 UCSF GRCh37 22 35659100 35659100 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 26 54 0 ENST00000216106.5:c.61G>A p.Asp21Asn p.D21N ENST00000216106 NM_001003681.2 21 Gac/Aac 0 +HMGXB4 UCSF GRCh37 22 35659836 35659836 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 20 61 0 ENST00000216106.5:c.228G>A p.Arg76= p.R76= ENST00000216106 NM_001003681.2 76 agG/agA 0 +HNRNPH2 UCSF GRCh37 X 100668241 100668241 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 139 166 0 ENST00000316594.5:c.1265G>A p.Gly422Asp p.G422D ENST00000316594 NM_001199974.1 422 gGt/gAt 0 +HNRNPU UCSF GRCh37 1 245021367 245021367 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 49 73 0 ENST00000283179.9:c.1440C>T p.Pro480= p.P480= ENST00000283179 480 ccC/ccT 0 +HOOK3 UCSF GRCh37 8 42868530 42868530 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 48 51 0 ENST00000307602.4:c.2003C>T p.Ala668Val p.A668V ENST00000307602 NM_032410.3 668 gCc/gTc 0 +HOXB3 UCSF GRCh37 17 46628137 46628137 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 150 70 50 0 ENST00000470495.1:c.855C>T p.Ser285= p.S285= ENST00000470495 285 agC/agT 0 +HOXD4 UCSF GRCh37 2 177017514 177017514 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 178 83 84 0 ENST00000306324.3:c.612C>T p.Asn204= p.N204= ENST00000306324 NM_014621.2 204 aaC/aaT 0 +HPN UCSF GRCh37 19 35556929 35556929 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 119 51 63 0 ENST00000262626.2:c.1208C>T p.Ala403Val p.A403V ENST00000262626 NM_182983.2 403 gCc/gTc 0 +HPS1 UCSF GRCh37 10 100183425 100183425 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 85 82 0 ENST00000325103.6:c.1533G>A p.Arg511= p.R511= ENST00000325103 NM_000195.3 511 cgG/cgA 0 +HRC UCSF GRCh37 19 49657604 49657604 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 33 33 0 ENST00000252825.4:c.891C>T p.His297= p.H297= ENST00000252825 NM_002152.2 297 caC/caT 0 +HRH2 UCSF GRCh37 5 175110320 175110320 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 81 149 0 ENST00000377291.2:c.84C>T p.Leu28= p.L28= ENST00000377291 NM_001131055.1 28 ctC/ctT 0 +HSD17B13 UCSF GRCh37 4 88231402 88231402 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 29 47 0 ENST00000328546.4:c.805C>T p.Leu269= p.L269= ENST00000328546 NM_178135.3 269 Cta/Tta 0 +HSF4 UCSF GRCh37 16 67199654 67199654 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 31 12 0 ENST00000264009.8:c.265G>A p.Gly89Ser p.G89S ENST00000264009 NM_001040667.2 89 Ggc/Agc 0 +HSPA5 UCSF GRCh37 9 127999235 127999235 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 130 63 154 0 ENST00000324460.6:c.1601C>T p.Thr534Ile p.T534I ENST00000324460 NM_005347.4 534 aCa/aTa 0 +HSPB1 UCSF GRCh37 7 75933374 75933374 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 11 13 0 ENST00000248553.6:c.502C>T p.Pro168Ser p.P168S ENST00000248553 NM_001540.3 168 Ccc/Tcc 0 +HSPBAP1 UCSF GRCh37 3 122459251 122459251 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 32 82 0 ENST00000306103.2:c.1408G>A p.Val470Met p.V470M ENST00000306103 NM_024610.5 470 Gtg/Atg 0 +HSPBP1 UCSF GRCh37 19 55790887 55790888 + inframe_insertion In_Frame_Ins INS - - GCCGCCGCC snp132_rs71743637 P05_Rec Untested WXS Illumina HiSeq 8 0 ENST00000255631.5:c.89_90insGGCGGCGGC p.Gly30_Ser31insAlaAlaAla p.G30_S31insAAA ENST00000255631 NM_012267.4 30 ggc/ggGGCGGCGGCc 0 +HSPG2 UCSF GRCh37 1 22150810 22150810 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 55 38 0 ENST00000374695.3:c.12804C>T p.His4268= p.H4268= ENST00000374695 NM_005529.5 4268 caC/caT 0 +HSPG2 UCSF GRCh37 1 22222744 22222744 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 135 74 114 0 ENST00000374695.3:c.123C>T p.Val41= p.V41= ENST00000374695 NM_005529.5 41 gtC/gtT 0 +HTR1B UCSF GRCh37 6 78172409 78172409 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 37 67 0 ENST00000369947.2:c.712C>T p.Arg238Trp p.R238W ENST00000369947 NM_000863.1 238 Cgg/Tgg 0 +HTR7 UCSF GRCh37 10 92503445 92503445 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 36 72 0 ENST00000336152.3:c.1298G>A p.Arg433Lys p.R433K ENST00000336152 NM_019859.3 433 aGg/aAg 0 +HTT UCSF GRCh37 4 3215750 3215750 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 27 29 0 ENST00000355072.5:c.6840C>T p.Asp2280= p.D2280= ENST00000355072 NM_002111.6 2280 gaC/gaT 0 +HVCN1 UCSF GRCh37 12 111099232 111099232 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 34 40 0 ENST00000356742.5:c.43G>A p.Val15Met p.V15M ENST00000356742 15 Gtg/Atg 0 +HVCN1 UCSF GRCh37 12 111099099 111099099 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 18 44 0 ENST00000356742.5:c.176C>T p.Pro59Leu p.P59L ENST00000356742 59 cCc/cTc 0 +HYDIN UCSF GRCh37 16 70867797 70867797 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 6 27 0 ENST00000393567.2:c.13672G>A p.Gly4558Ser p.G4558S ENST00000393567 NM_001270974.1 4558 Ggt/Agt 0 +HYDIN UCSF GRCh37 16 70871667 70871667 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 22 90 0 ENST00000393567.2:c.13168G>A p.Glu4390Lys p.E4390K ENST00000393567 NM_001270974.1 4390 Gaa/Aaa 0 +HYDIN UCSF GRCh37 16 70996005 70996005 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 141 24 122 0 ENST00000393567.2:c.5825C>T p.Ser1942Phe p.S1942F ENST00000393567 NM_001270974.1 1942 tCc/tTc 0 +HYDIN UCSF GRCh37 16 70972528 70972528 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 234 64 91 0 ENST00000393567.2:c.6984G>A p.Glu2328= p.E2328= ENST00000393567 NM_001270974.1 2328 gaG/gaA 0 +HYOU1 UCSF GRCh37 11 118922844 118922844 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 49 52 0 ENST00000404233.3:c.1163G>A p.Arg388Gln p.R388Q ENST00000404233 NM_001130991.1 388 cGg/cAg 0 +IBTK UCSF GRCh37 6 82912255 82912255 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 145 92 100 0 ENST00000306270.7:c.2719C>T p.Leu907Phe p.L907F ENST00000306270 NM_015525.2 907 Ctt/Ttt 0 +ICAM4 UCSF GRCh37 19 10398503 10398503 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 64 51 0 ENST00000340992.4:c.609C>T p.Tyr203= p.Y203= ENST00000340992 NM_001039132.2 203 taC/taT 0 +ICAM5 UCSF GRCh37 19 10402332 10402332 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 110 61 41 0 ENST00000221980.4:c.520C>T p.Pro174Ser p.P174S ENST00000221980 NM_003259.3 174 Ccc/Tcc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 26 75 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IDH3A UCSF GRCh37 15 78452452 78452452 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 55 70 0 ENST00000299518.2:c.193G>A p.Glu65Lys p.E65K ENST00000299518 NM_005530.2 65 Gag/Aag 0 +IFI44L UCSF GRCh37 1 79107151 79107151 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 43 49 0 ENST00000370751.5:c.1181C>T p.Pro394Leu p.P394L ENST00000370751 NM_006820.2 394 cCt/cTt 0 +IFIT1 UCSF GRCh37 10 91163308 91163308 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 39 73 0 ENST00000371804.3:c.1276G>A p.Val426Ile p.V426I ENST00000371804 NM_001270927.1 426 Gtt/Att 0 +IFRD2 UCSF GRCh37 3 50327620 50327620 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 54 44 0 ENST00000429673.2:c.561G>A p.Leu187= p.L187= ENST00000429673 187 ctG/ctA 0 +IFT122 UCSF GRCh37 3 129234339 129234339 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 29 34 0 ENST00000296266.3:c.3315G>A p.Val1105= p.V1105= ENST00000296266 NM_052985.3 1105 gtG/gtA 0 +IFT81 UCSF GRCh37 12 110600794 110600794 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 33 81 0 ENST00000242591.5:c.1112G>A p.Ser371Asn p.S371N ENST00000242591 NM_014055.3 371 aGc/aAc 0 +IGFBPL1 UCSF GRCh37 9 38411424 38411424 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 32 59 0 ENST00000377694.1:c.810C>T p.His270= p.H270= ENST00000377694 NM_001007563.2 270 caC/caT 0 +IGFN1 UCSF GRCh37 1 201190766 201190766 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 17 20 0 ENST00000335211.4:c.10093G>A p.Gly3365Arg p.G3365R ENST00000335211 NM_001164586.1 3365 Ggg/Agg 0 +IGFN1 UCSF GRCh37 1 201183324 201183324 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 17 31 0 ENST00000335211.4:c.8748C>T p.Ser2916= p.S2916= ENST00000335211 NM_001164586.1 2916 tcC/tcT 0 +IGSF3 UCSF GRCh37 1 117150657 117150657 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 48 159 0 ENST00000369483.1:c.1129C>T p.Arg377Trp p.R377W ENST00000369483 NM_001542.3 377 Cgg/Tgg 0 +IGSF9 UCSF GRCh37 1 159898250 159898250 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 13 6 9 0 ENST00000368094.1:c.2928C>T p.Ser976= p.S976= ENST00000368094 NM_001135050.1 976 tcC/tcT 0 +IKBIP UCSF GRCh37 12 99007524 99007524 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 55 94 0 ENST00000342502.2:c.892G>A p.Val298Ile p.V298I ENST00000342502 NM_201612.2 298 Gta/Ata 0 +IL17RD UCSF GRCh37 3 57131798 57131798 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 143 39 36 0 ENST00000296318.7:c.1933C>T p.Pro645Ser p.P645S ENST00000296318 NM_017563.3 645 Ccc/Tcc 0 +IL17RD UCSF GRCh37 3 57140020 57140020 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 151 39 89 0 ENST00000296318.7:c.612C>T p.Asn204= p.N204= ENST00000296318 NM_017563.3 204 aaC/aaT 0 +IL1F10 UCSF GRCh37 2 113832830 113832830 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 50 58 0 ENST00000393197.2:c.348C>T p.Ala116= p.A116= ENST00000393197 NM_032556.5 116 gcC/gcT 0 +IL1R2 UCSF GRCh37 2 102642637 102642637 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 44 88 0 ENST00000332549.3:c.952G>A p.Glu318Lys p.E318K ENST00000332549 NM_004633.3 318 Gag/Aag 0 +IL1RL1 UCSF GRCh37 2 102968206 102968206 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 33 59 0 ENST00000233954.1:c.1496C>T p.Ser499Phe p.S499F ENST00000233954 NM_016232.4 499 tCc/tTc 0 +IL27RA UCSF GRCh37 19 14160068 14160068 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 22 43 0 ENST00000263379.2:c.1344C>T p.His448= p.H448= ENST00000263379 NM_004843.3 448 caC/caT 0 +IL27RA UCSF GRCh37 19 14162973 14162973 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 4 10 0 ENST00000263379.2:c.1782G>A p.Pro594= p.P594= ENST00000263379 NM_004843.3 594 ccG/ccA 0 +ILVBL UCSF GRCh37 19 15234266 15234266 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 68 55 31 0 ENST00000263383.3:c.257A>C p.Glu86Ala p.E86A ENST00000263383 NM_006844.4 86 gAg/gCg 0 +IMPA1 UCSF GRCh37 8 82583203 82583203 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 15 24 0 ENST00000449740.2:c.714G>A p.Met238Ile p.M238I ENST00000449740 NM_001144878.1 238 atG/atA 0 +IMPDH1 UCSF GRCh37 7 128040521 128040521 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 14 12 0 ENST00000338791.6:c.652G>A p.Ala218Thr p.A218T ENST00000338791 NM_000883.3 218 Gcc/Acc 0 +IMPDH2 UCSF GRCh37 3 49065942 49065942 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 18 37 0 ENST00000326739.4:c.171G>A p.Lys57= p.K57= ENST00000326739 NM_000884.2 57 aaG/aaA 0 +INO80 UCSF GRCh37 15 41313250 41313250 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 50 57 0 ENST00000361937.3:c.3122G>A p.Gly1041Glu p.G1041E ENST00000361937 1041 gGa/gAa 0 +INPP4B UCSF GRCh37 4 143033752 143033752 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 75 56 92 0 ENST00000262992.4:c.2219A>G p.His740Arg p.H740R ENST00000262992 NM_001101669.1 740 cAt/cGt 0 +INPP5F UCSF GRCh37 10 121582651 121582651 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 12 22 36 0 ENST00000361976.2:c.2101G>A p.Ala701Thr p.A701T ENST00000361976 NM_014937.3 701 Gcg/Acg 0 +INPPL1 UCSF GRCh37 11 71940181 71940181 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 37 26 0 ENST00000298229.2:c.566G>A p.Ser189Asn p.S189N ENST00000298229 NM_001567.3 189 aGc/aAc 0 +INSRR UCSF GRCh37 1 156823907 156823907 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 35 26 0 ENST00000368195.3:c.274G>A p.Glu92Lys p.E92K ENST00000368195 NM_014215.2 92 Gag/Aag 0 +INSRR UCSF GRCh37 1 156815549 156815549 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 25 11 0 ENST00000368195.3:c.2036C>T p.Pro679Leu p.P679L ENST00000368195 NM_014215.2 679 cCt/cTt 0 +INTS1 UCSF GRCh37 7 1511251 1511251 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 59 76 0 ENST00000404767.3:c.6211G>A p.Asp2071Asn p.D2071N ENST00000404767 NM_001080453.2 2071 Gac/Aac 0 +INTS1 UCSF GRCh37 7 1516226 1516226 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 17 30 0 ENST00000404767.3:c.5131C>T p.Arg1711Trp p.R1711W ENST00000404767 NM_001080453.2 1711 Cgg/Tgg 0 +INTS5 UCSF GRCh37 11 62415154 62415154 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 131 64 41 0 ENST00000330574.2:c.2398G>A p.Gly800Arg p.G800R ENST00000330574 NM_030628.1 800 Ggg/Agg 0 +IQCC UCSF GRCh37 1 32673044 32673044 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 27 43 0 ENST00000537469.1:c.1002C>T p.Pro334= p.P334= ENST00000537469 NM_001160042.1 334 ccC/ccT 0 +IQCH UCSF GRCh37 15 67692463 67692463 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 28 48 0 ENST00000335894.4:c.1917G>A p.Gln639= p.Q639= ENST00000335894 NM_001031715.2 639 caG/caA 0 +IRAK1BP1 UCSF GRCh37 6 79607818 79607818 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 39 83 0 ENST00000369940.2:c.550C>T p.Arg184Cys p.R184C ENST00000369940 NM_001010844.3 184 Cgc/Tgc 0 +IRF9 UCSF GRCh37 14 24632661 24632661 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 81 135 0 ENST00000396864.3:c.439G>A p.Asp147Asn p.D147N ENST00000396864 NM_006084.4 147 Gat/Aat 0 +IRGC UCSF GRCh37 19 44222793 44222793 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 48 37 0 ENST00000244314.5:c.83G>A p.Arg28His p.R28H ENST00000244314 NM_019612.3 28 cGc/cAc 0 +IRS1 UCSF GRCh37 2 227663066 227663066 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 59 28 0 ENST00000305123.5:c.389G>A p.Gly130Glu p.G130E ENST00000305123 NM_005544.2 130 gGa/gAa 0 +IRS4 UCSF GRCh37 X 107977851 107977851 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 93 92 0 ENST00000372129.2:c.1724G>A p.Gly575Glu p.G575E ENST00000372129 NM_003604.2 575 gGa/gAa 0 +IRX5 UCSF GRCh37 16 54965234 54965234 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 13 14 0 ENST00000394636.4:c.124G>A p.Gly42Ser p.G42S ENST00000394636 42 Ggc/Agc 0 +ISX UCSF GRCh37 22 35463225 35463225 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.031,1000g2011may_all_0.06778,snp132_rs61739193 P05_Rec Untested WXS Illumina HiSeq 14 6 11 0 ENST00000308700.6:c.145C>T p.Pro49Ser p.P49S ENST00000308700 NM_001008494.1 49 Cca/Tca 0 +ITGA11 UCSF GRCh37 15 68654023 68654023 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 29 68 0 ENST00000315757.7:c.377C>T p.Ser126Phe p.S126F ENST00000315757 NM_001004439.1 126 tCt/tTt 0 +ITGA2 UCSF GRCh37 5 52361693 52361693 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 32 73 0 ENST00000296585.5:c.1829C>T p.Ala610Val p.A610V ENST00000296585 NM_002203.3 610 gCc/gTc 0 +ITGA3 UCSF GRCh37 17 48156278 48156278 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 45 66 0 ENST00000007722.7:c.2388G>A p.Lys796= p.K796= ENST00000007722 796 aaG/aaA 0 +ITGA7 UCSF GRCh37 12 56086663 56086663 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 6 22 0 ENST00000553804.1:c.2821G>A p.Val941Met p.V941M ENST00000553804 NM_001144996.1 941 Gtg/Atg 0 +ITGAE UCSF GRCh37 17 3662819 3662819 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 21 79 0 ENST00000263087.4:c.743G>A p.Gly248Glu p.G248E ENST00000263087 NM_002208.4 248 gGa/gAa 0 +ITGAM UCSF GRCh37 16 31341204 31341204 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 27 39 0 ENST00000544665.3:c.2957G>A p.Arg986His p.R986H ENST00000544665 NM_001145808.1 986 cGc/cAc 0 +ITGAX UCSF GRCh37 16 31392317 31392317 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 24 26 0 ENST00000268296.4:c.3376G>A p.Val1126Ile p.V1126I ENST00000268296 NM_000887.3 1126 Gta/Ata 0 +ITPR2 UCSF GRCh37 12 26493114 26493114 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 28 59 0 ENST00000381340.3:c.8005G>A p.Glu2669Lys p.E2669K ENST00000381340 NM_002223.2 2669 Gag/Aag 0 +ITPR3 UCSF GRCh37 6 33661398 33661398 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 36 30 0 ENST00000374316.5:c.7701C>T p.Asn2567= p.N2567= ENST00000374316 2567 aaC/aaT 0 +ITSN1 UCSF GRCh37 21 35153812 35153812 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 28 43 0 ENST00000381318.3:c.1644C>T p.Leu548= p.L548= ENST00000381318 NM_003024.2 548 ctC/ctT 0 +JAG1 UCSF GRCh37 20 10622514 10622514 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 135 70 105 0 ENST00000254958.5:c.2599G>A p.Gly867Arg p.G867R ENST00000254958 NM_000214.2 867 Ggg/Agg 0 +JAG2 UCSF GRCh37 14 105609353 105609353 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 3 13 0 ENST00000331782.3:c.3396C>T p.Asn1132= p.N1132= ENST00000331782 NM_002226.4 1132 aaC/aaT 0 +JAZF1 UCSF GRCh37 7 27880336 27880336 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 273 67 102 0 ENST00000283928.5:c.536G>A p.Gly179Glu p.G179E ENST00000283928 NM_175061.3 179 gGa/gAa 0 +JHDM1D UCSF GRCh37 7 139798772 139798772 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 34 62 0 ENST00000397560.2:c.1825G>A p.Asp609Asn p.D609N ENST00000397560 NM_030647.1 609 Gat/Aat 0 +JUP UCSF GRCh37 17 39919560 39919560 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 30 19 0 ENST00000393931.3:c.1172G>A p.Ser391Asn p.S391N ENST00000393931 NM_002230.2 391 aGt/aAt 0 +KANK4 UCSF GRCh37 1 62740403 62740403 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 30 43 0 ENST00000371153.4:c.373G>A p.Val125Met p.V125M ENST00000371153 NM_181712.4 125 Gtg/Atg 0 +KBTBD8 UCSF GRCh37 3 67054544 67054544 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 56 147 0 ENST00000417314.2:c.1153C>T p.Leu385Phe p.L385F ENST00000417314 385 Ctt/Ttt 0 +KCMF1 UCSF GRCh37 2 85276656 85276656 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 135 92 104 0 ENST00000409785.4:c.769C>T p.Arg257Cys p.R257C ENST00000409785 NM_020122.4 257 Cgt/Tgt 0 +KCMF1 UCSF GRCh37 2 85270743 85270743 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 36 58 0 ENST00000409785.4:c.381C>T p.Asp127= p.D127= ENST00000409785 NM_020122.4 127 gaC/gaT 0 +KCND3 UCSF GRCh37 1 112525199 112525199 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 72 27 0 ENST00000315987.2:c.150G>A p.Arg50= p.R50= ENST00000315987 NM_004980.4 50 agG/agA 0 +KCNG4 UCSF GRCh37 16 84270739 84270739 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 140 49 30 0 ENST00000308251.4:c.353G>A p.Ser118Asn p.S118N ENST00000308251 NM_172347.2 118 aGc/aAc 0 +KCNH8 UCSF GRCh37 3 19492678 19492678 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 135 58 132 0 ENST00000328405.2:c.1607C>T p.Ser536Phe p.S536F ENST00000328405 NM_144633.2 536 tCt/tTt 0 +KCNK2 UCSF GRCh37 1 215298076 215298076 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 67 152 0 ENST00000444842.2:c.458C>T p.Thr153Ile p.T153I ENST00000444842 NM_014217.3 153 aCt/aTt 0 +KCNQ2 UCSF GRCh37 20 62073779 62073779 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 238 126 156 0 ENST00000359125.2:c.796G>A p.Asp266Asn p.D266N ENST00000359125 NM_172107.2 266 Gat/Aat 0 +KCNQ2 UCSF GRCh37 20 62046413 62046413 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 35 24 0 ENST00000359125.2:c.1368G>A p.Gly456= p.G456= ENST00000359125 NM_172107.2 456 ggG/ggA 0 +KCNT1 UCSF GRCh37 9 138656883 138656883 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 21 25 0 ENST00000371757.2:c.1042G>A p.Glu348Lys p.E348K ENST00000371757 NM_020822.2 348 Gag/Aag 0 +KCTD19 UCSF GRCh37 16 67325605 67325605 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 23 33 0 ENST00000304372.5:c.2354C>T p.Thr785Ile p.T785I ENST00000304372 NM_001100915.1 785 aCc/aTc 0 +KCTD20 UCSF GRCh37 6 36454777 36454777 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 165 94 146 0 ENST00000373731.2:c.1085G>A p.Ser362Asn p.S362N ENST00000373731 NM_173562.3 362 aGt/aAt 0 +KCTD6 UCSF GRCh37 3 58487273 58487273 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 19 46 0 ENST00000355076.6:c.628G>A p.Val210Met p.V210M ENST00000355076 NM_153331.3 210 Gtg/Atg 0 +KDR UCSF GRCh37 4 55955592 55955592 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 18 26 0 ENST00000263923.4:c.3353G>A p.Arg1118Gln p.R1118Q ENST00000263923 NM_002253.2 1118 cGa/cAa 0 +KEL UCSF GRCh37 7 142641460 142641460 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 32 55 0 ENST00000355265.2:c.1441G>A p.Ala481Thr p.A481T ENST00000355265 NM_000420.2 481 Gct/Act 0 +KIAA0020 UCSF GRCh37 9 2804383 2804383 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 33 69 0 ENST00000397885.2:c.1895C>A p.Thr632Asn p.T632N ENST00000397885 NM_014878.4 632 aCc/aAc 0 +KIAA0182 UCSF GRCh37 16 85699735 85699735 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 38 52 0 ENST00000253458.7:c.2912G>A p.Gly971Glu p.G971E ENST00000253458 NM_014615.3 971 gGg/gAg 0 +KIAA0319L UCSF GRCh37 1 35972342 35972342 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 55 108 0 ENST00000325722.3:c.537G>A p.Gln179= p.Q179= ENST00000325722 NM_024874.4 179 caG/caA 0 +KIAA0430 UCSF GRCh37 16 15709764 15709764 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 45 78 0 ENST00000396368.3:c.3176G>A p.Gly1059Asp p.G1059D ENST00000396368 NM_001184998.1 1059 gGt/gAt 0 +KIAA0430 UCSF GRCh37 16 15715650 15715650 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 30 37 0 ENST00000396368.3:c.2579G>A p.Ser860Asn p.S860N ENST00000396368 NM_001184998.1 860 aGc/aAc 0 +KIAA0494 UCSF GRCh37 1 47173724 47173724 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 35 43 0 ENST00000371933.3:c.335-1G>A p.X112_splice ENST00000371933 NM_014774.2 0 +KIAA0754 UCSF GRCh37 1 39878149 39878149 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 55 90 0 ENST00000530275.1:c.1804C>T p.His602Tyr p.H602Y ENST00000530275 NM_015038.1 602 Cat/Tat 0 +KIAA0754 UCSF GRCh37 1 39879913 39879913 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 27 21 0 ENST00000530275.1:c.3568G>A p.Val1190Met p.V1190M ENST00000530275 NM_015038.1 1190 Gtg/Atg 0 +KIAA1009 UCSF GRCh37 6 84862522 84862522 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 220 141 232 0 ENST00000403245.3:c.3371C>T p.Ser1124Leu p.S1124L ENST00000403245 NM_014895.2 1124 tCa/tTa 0 +KIAA1024 UCSF GRCh37 15 79749460 79749460 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 142 90 157 0 ENST00000305428.3:c.971G>A p.Arg324Lys p.R324K ENST00000305428 NM_015206.2 324 aGg/aAg 0 +KIAA1024 UCSF GRCh37 15 79760642 79760642 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 17 34 0 ENST00000305428.3:c.2667C>T p.Val889= p.V889= ENST00000305428 NM_015206.2 889 gtC/gtT 0 +KIAA1033 UCSF GRCh37 12 105534999 105534999 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 56 91 0 ENST00000332180.5:c.1762G>A p.Asp588Asn p.D588N ENST00000332180 NM_015275.1 588 Gat/Aat 0 +KIAA1109 UCSF GRCh37 4 123268748 123268748 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 47 57 0 ENST00000264501.4:c.12943G>A p.Ala4315Thr p.A4315T ENST00000264501 4315 Gct/Act 0 +KIAA1147 UCSF GRCh37 7 141386458 141386458 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 34 68 0 ENST00000536163.1:c.269G>A p.Gly90Glu p.G90E ENST00000536163 NM_001080392.1 90 gGa/gAa 0 +KIAA1239 UCSF GRCh37 4 37440874 37440874 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 72 162 0 ENST00000309447.5:c.1158C>T p.Phe386= p.F386= ENST00000309447 NM_001144990.1 386 ttC/ttT 0 +KIAA1267 UCSF GRCh37 17 44249494 44249494 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 36 26 0 ENST00000262419.6:c.16C>T p.Pro6Ser p.P6S ENST00000262419 NM_001193466.1 6 Ccc/Tcc 0 +KIAA1279 UCSF GRCh37 10 70748592 70748592 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 62 37 0 ENST00000361983.4:c.4G>A p.Ala2Thr p.A2T ENST00000361983 NM_015634.3 2 Gcg/Acg 0 +KIAA1407 UCSF GRCh37 3 113729717 113729717 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 74 105 0 ENST00000295878.3:c.1315G>A p.Ala439Thr p.A439T ENST00000295878 NM_020817.1 439 Gca/Aca 0 +KIAA1462 UCSF GRCh37 10 30316188 30316188 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 148 58 77 0 ENST00000375377.1:c.2889C>T p.Asn963= p.N963= ENST00000375377 NM_020848.2 963 aaC/aaT 0 +KIAA1530 UCSF GRCh37 4 1348558 1348558 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 19 23 0 ENST00000389851.4:c.970G>A p.Ala324Thr p.A324T ENST00000389851 NM_020894.2 324 Gct/Act 0 +KIAA1549 UCSF GRCh37 7 138595914 138595914 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 133 27 106 0 ENST00000422774.1:c.3123G>A p.Glu1041= p.E1041= ENST00000422774 1041 gaG/gaA 0 +KIAA1671 UCSF GRCh37 22 25577768 25577768 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 26 19 0 ENST00000358431.3:c.5177G>A p.Gly1726Asp p.G1726D ENST00000358431 NM_001145206.1 1726 gGc/gAc 0 +KIAA1683 UCSF GRCh37 19 18377383 18377383 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 56 76 0 ENST00000392413.4:c.967C>T p.Pro323Ser p.P323S ENST00000392413 NM_001145304.1 323 Ccc/Tcc 0 +KIAA1751 UCSF GRCh37 1 1905497 1905497 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 17 11 0 ENST00000270720.7:n.797G>A *266* ENST00000270720 0 +KIAA1751 UCSF GRCh37 1 1900103 1900104 + non_coding_transcript_exon_variant RNA INS - - TCT NOVEL P05_Rec Untested WXS Illumina HiSeq 6 0 ENST00000270720.7:n.1372_1373insGAA *458* ENST00000270720 0 +KIAA1804 UCSF GRCh37 1 233511670 233511670 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 21 46 0 ENST00000366624.3:c.1684G>A p.Asp562Asn p.D562N ENST00000366624 NM_032435.2 562 Gat/Aat 0 +KIAA2018 UCSF GRCh37 3 113377353 113377353 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 143 48 161 0 ENST00000316407.4:c.3176G>A p.Arg1059Lys p.R1059K ENST00000316407 NM_001009899.2 1059 aGa/aAa 0 +KIAA2018 UCSF GRCh37 3 113377515 113377515 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 60 137 0 ENST00000316407.4:c.3014C>T p.Thr1005Ile p.T1005I ENST00000316407 NM_001009899.2 1005 aCt/aTt 0 +KIAA2022 UCSF GRCh37 X 73962030 73962030 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 123 70 140 0 ENST00000055682.6:c.2362C>T p.Leu788= p.L788= ENST00000055682 NM_001008537.2 788 Cta/Tta 0 +KIF18B UCSF GRCh37 17 43009482 43009482 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 20 48 0 ENST00000593135.1:c.1331G>A p.Gly444Glu p.G444E ENST00000593135 NM_001265577.1 444 gGg/gAg 0 +KIF1B UCSF GRCh37 1 10386370 10386370 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 54 59 0 ENST00000263934.6:c.2739G>A p.Gly913= p.G913= ENST00000263934 NM_015074.3 913 ggG/ggA 0 +KIF21B UCSF GRCh37 1 200945916 200945916 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 18 16 0 ENST00000422435.2:c.4431C>T p.Asp1477= p.D1477= ENST00000422435 NM_001252100.1 1477 gaC/gaT 0 +KIF23 UCSF GRCh37 15 69728990 69728990 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 40 41 0 ENST00000260363.4:c.1484C>T p.Pro495Leu p.P495L ENST00000260363 NM_138555.3 495 cCa/cTa 0 +KIF24 UCSF GRCh37 9 34256456 34256456 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 121 73 87 0 ENST00000379166.2:c.3149C>T p.Ser1050Phe p.S1050F ENST00000379166 NM_194313.2 1050 tCt/tTt 0 +KIF26A UCSF GRCh37 14 104641411 104641411 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 13 9 0 ENST00000423312.2:c.2286G>A p.Val762= p.V762= ENST00000423312 NM_015656.1 762 gtG/gtA 0 +KIF26B UCSF GRCh37 1 245849530 245849530 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 133 72 63 0 ENST00000407071.2:c.3245C>T p.Pro1082Leu p.P1082L ENST00000407071 NM_018012.3 1082 cCc/cTc 0 +KIF2C UCSF GRCh37 1 45232509 45232509 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 39 22 46 0 ENST00000372224.4:c.1983C>T p.Asp661= p.D661= ENST00000372224 NM_006845.3 661 gaC/gaT 0 +KIF6 UCSF GRCh37 6 39398905 39398905 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 11 32 0 ENST00000287152.7:c.1678G>A p.Glu560Lys p.E560K ENST00000287152 NM_145027.4 560 Gag/Aag 0 +KIFC3 UCSF GRCh37 16 57805320 57805320 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 332 121 87 0 ENST00000379655.4:c.555C>T p.Ser185= p.S185= ENST00000379655 NM_005550.3 185 tcC/tcT 0 +KIT UCSF GRCh37 4 55573358 55573358 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 23 55 0 ENST00000288135.5:c.1020C>T p.Phe340= p.F340= ENST00000288135 NM_000222.2 340 ttC/ttT 0 +KLF11 UCSF GRCh37 2 10188080 10188080 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 52 99 0 ENST00000305883.1:c.616C>T p.Gln206Ter p.Q206* ENST00000305883 NM_003597.4 206 Cag/Tag 0 +KLHDC7A UCSF GRCh37 1 18808738 18808738 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 46 22 0 ENST00000400664.1:c.1263C>T p.Thr421= p.T421= ENST00000400664 NM_152375.2 421 acC/acT 0 +KLHDC7A UCSF GRCh37 1 18808561 18808561 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 28 28 19 0 ENST00000400664.1:c.1086G>A p.Arg362= p.R362= ENST00000400664 NM_152375.2 362 cgG/cgA 0 +KLHDC8A UCSF GRCh37 1 205306545 205306545 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 34 61 0 ENST00000367156.3:c.1035G>A p.Leu345= p.L345= ENST00000367156 NM_001271863.1 345 ctG/ctA 0 +KLHL18 UCSF GRCh37 3 47361194 47361194 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 46 89 0 ENST00000232766.5:c.181C>T p.Pro61Ser p.P61S ENST00000232766 NM_025010.4 61 Ccg/Tcg 0 +KLHL8 UCSF GRCh37 4 88116599 88116599 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 54 98 0 ENST00000273963.5:c.93C>T p.Ser31= p.S31= ENST00000273963 NM_020803.3 31 tcC/tcT 0 +KLHL9 UCSF GRCh37 9 21333274 21333274 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 137 109 201 0 ENST00000359039.4:c.1585G>A p.Ala529Thr p.A529T ENST00000359039 529 Gcc/Acc 0 +KLHL9 UCSF GRCh37 9 21334451 21334451 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 130 15 76 0 ENST00000359039.4:c.408C>T p.Pro136= p.P136= ENST00000359039 136 ccC/ccT 0 +KLK1 UCSF GRCh37 19 51325008 51325008 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 11 20 0 ENST00000301420.2:c.166C>T p.His56Tyr p.H56Y ENST00000301420 NM_002257.3 56 Cac/Tac 0 +KLRAQ1 UCSF GRCh37 2 48688356 48688356 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 27 43 0 ENST00000294952.8:c.679C>T p.Pro227Ser p.P227S ENST00000294952 NM_001135629.2 227 Cct/Tct 0 +KPNA1 UCSF GRCh37 3 122172726 122172726 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 11 39 0 ENST00000344337.6:c.555C>T p.Val185= p.V185= ENST00000344337 NM_002264.3 185 gtC/gtT 0 +KPTN UCSF GRCh37 19 47978723 47978723 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 14 8 0 ENST00000338134.3:c.1261G>A p.Gly421Arg p.G421R ENST00000338134 NM_007059.2 421 Ggg/Agg 0 +KPTN UCSF GRCh37 19 47987232 47987232 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 45 21 0 ENST00000338134.3:c.186C>T p.Ile62= p.I62= ENST00000338134 NM_007059.2 62 atC/atT 0 +KRT10 UCSF GRCh37 17 38978210 38978210 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 54 130 0 ENST00000269576.5:c.627+1G>A p.X209_splice ENST00000269576 NM_000421.3 0 +KRT12 UCSF GRCh37 17 39019780 39019780 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 48 45 0 ENST00000251643.4:c.1052C>T p.Ala351Val p.A351V ENST00000251643 NM_000223.3 351 gCc/gTc 0 +KRT24 UCSF GRCh37 17 38859558 38859558 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 166 99 115 0 ENST00000264651.2:c.388G>A p.Val130Ile p.V130I ENST00000264651 NM_019016.2 130 Gtt/Att 0 +KRT33A UCSF GRCh37 17 39506671 39506671 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 48 67 0 ENST00000007735.3:c.348+1G>A p.X116_splice ENST00000007735 NM_004138.3 0 +KRT33A UCSF GRCh37 17 39503373 39503373 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 57 34 49 0 ENST00000007735.3:c.690T>C p.Ser230= p.S230= ENST00000007735 NM_004138.3 230 agT/agC 0 +KRT85 UCSF GRCh37 12 52756135 52756135 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 50 61 0 ENST00000257901.3:c.1198G>A p.Ala400Thr p.A400T ENST00000257901 NM_002283.3 400 Gcc/Acc 0 +KRTAP4-8 UCSF GRCh37 17 39254082 39254082 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 130 45 47 0 ENST00000333822.4:c.255C>T p.Cys85= p.C85= ENST00000333822 NM_031960.2 85 tgC/tgT 0 +KRTAP9-1 UCSF GRCh37 17 39346626 39346627 + protein_altering_variant In_Frame_Ins INS - - GTGGGTCCAGCTGCTGCCAGCCTTGCT NOVEL P05_Rec Untested WXS Illumina HiSeq 8 0 ENST00000398470.1:c.488_489insGTGGGTCCAGCTGCTGCCAGCCTTGCT p.Cys163delinsTrpTrpValGlnLeuLeuProAlaLeuLeu p.C163delinsWWVQLLPALL ENST00000398470 NM_001190460.1 163 tgc/tgGTGGGTCCAGCTGCTGCCAGCCTTGCTc 0 +KRTDAP UCSF GRCh37 19 35981326 35981326 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 21 31 0 ENST00000338897.3:c.19C>T p.Pro7Ser p.P7S ENST00000338897 NM_207392.2 7 Cct/Tct 0 +KTI12 UCSF GRCh37 1 52498894 52498894 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 126 65 53 0 ENST00000371614.1:c.540G>A p.Gly180= p.G180= ENST00000371614 NM_138417.2 180 ggG/ggA 0 +L3MBTL2 UCSF GRCh37 22 41621036 41621036 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 40 34 0 ENST00000216237.5:c.1317C>T p.Pro439= p.P439= ENST00000216237 NM_031488.4 439 ccC/ccT 0 +LAMA1 UCSF GRCh37 18 7043231 7043231 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 72 139 0 ENST00000389658.3:c.1150C>T p.His384Tyr p.H384Y ENST00000389658 NM_005559.3 384 Cac/Tac 0 +LAMB1 UCSF GRCh37 7 107601033 107601033 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 30 55 0 ENST00000222399.6:c.2171G>A p.Gly724Glu p.G724E ENST00000222399 NM_002291.2 724 gGg/gAg 0 +LAMB2 UCSF GRCh37 3 49168206 49168206 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 126 43 84 0 ENST00000418109.1:c.1003C>T p.Pro335Ser p.P335S ENST00000418109 NM_002292.3 335 Ccg/Tcg 0 +LAMB2 UCSF GRCh37 3 49160387 49160387 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 38 38 0 ENST00000418109.1:c.4323C>T p.Ser1441= p.S1441= ENST00000418109 NM_002292.3 1441 agC/agT 0 +LAMC3 UCSF GRCh37 9 133961052 133961052 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 24 31 0 ENST00000361069.4:c.4172C>T p.Ser1391Phe p.S1391F ENST00000361069 NM_006059.3 1391 tCc/tTc 0 +LAMC3 UCSF GRCh37 9 133944397 133944397 + stop_gained Nonsense_Mutation SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 144 50 37 0 ENST00000361069.4:c.2850C>A p.Cys950Ter p.C950* ENST00000361069 NM_006059.3 950 tgC/tgA 0 +LARP1 UCSF GRCh37 5 154181876 154181876 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 28 54 0 ENST00000336314.4:c.1795G>A p.Ala599Thr p.A599T ENST00000336314 NM_015315.4 599 Gcc/Acc 0 +LARP1B UCSF GRCh37 4 129012618 129012618 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 24 65 0 ENST00000326639.6:c.619G>A p.Val207Met p.V207M ENST00000326639 NM_018078.3 207 Gtg/Atg 0 +LATS2 UCSF GRCh37 13 21555650 21555650 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 18 51 0 ENST00000382592.4:c.2620G>A p.Val874Met p.V874M ENST00000382592 NM_014572.2 874 Gtg/Atg 0 +LAX1 UCSF GRCh37 1 203743271 203743271 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 29 57 0 ENST00000442561.2:c.659C>T p.Pro220Leu p.P220L ENST00000442561 NM_017773.3 220 cCc/cTc 0 +LAYN UCSF GRCh37 11 111414791 111414791 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 45 71 0 ENST00000375615.3:c.253G>A p.Asp85Asn p.D85N ENST00000375615 NM_001258390.1 85 Gat/Aat 0 +LAYN UCSF GRCh37 11 111425932 111425932 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 36 82 0 ENST00000375615.3:c.599G>A p.Gly200Asp p.G200D ENST00000375615 NM_001258390.1 200 gGt/gAt 0 +LCA5L UCSF GRCh37 21 40777899 40777899 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 29 36 0 ENST00000358268.2:c.1922C>T p.Thr641Ile p.T641I ENST00000358268 641 aCc/aTc 0 +LCA5L UCSF GRCh37 21 40778307 40778307 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 34 88 0 ENST00000358268.2:c.1514C>T p.Thr505Ile p.T505I ENST00000358268 505 aCa/aTa 0 +LCE1E UCSF GRCh37 1 152760093 152760093 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.064,1000g2011may_all_0.1443,snp132_rs112600788 P05_Rec Untested WXS Illumina HiSeq 100 15 24 0 ENST00000368770.3:c.318T>C p.Cys106= p.C106= ENST00000368770 NM_178353.1 106 tgT/tgC 0 +LCE5A UCSF GRCh37 1 152484018 152484018 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 112 61 71 0 ENST00000334269.2:c.8G>A p.Cys3Tyr p.C3Y ENST00000334269 NM_178438.4 3 tGc/tAc 0 +LCK UCSF GRCh37 1 32751132 32751132 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 21 42 0 ENST00000336890.5:c.1345G>A p.Val449Met p.V449M ENST00000336890 NM_005356.3 449 Gtg/Atg 0 +LCN10 UCSF GRCh37 9 139635365 139635365 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 35 30 0 ENST00000497771.1:c.398C>T p.Ser133Phe p.S133F ENST00000497771 NM_001001712.2 133 tCc/tTc 0 +LEMD1 UCSF GRCh37 1 205385359 205385359 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 45 39 0 ENST00000367153.4:c.270+1G>A p.X90_splice ENST00000367153 NM_001199050.1 0 +LEO1 UCSF GRCh37 15 52258437 52258437 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 76 135 0 ENST00000299601.5:c.323G>A p.Ser108Asn p.S108N ENST00000299601 NM_138792.2 108 aGt/aAt 0 +LETMD1 UCSF GRCh37 12 51445875 51445875 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 41 116 0 ENST00000418425.2:c.275G>A p.Gly92Glu p.G92E ENST00000418425 NM_001243689.1 92 gGa/gAa 0 +LILRB3 UCSF GRCh37 19 54725744 54725744 + stop_gained Nonsense_Mutation SNP C C T 1000g2011may_all_0.0238,snp132_rs59533602 P05_Rec Untested WXS Illumina HiSeq 45 8 24 0 ENST00000245620.9:c.614G>A p.Trp205Ter p.W205* ENST00000245620 205 tGg/tAg 0 +LILRB3 UCSF GRCh37 19 54725755 54725755 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.020,1000g2011may_all_0.1385,snp132_rs1052971 P05_Rec Untested WXS Illumina HiSeq 43 7 20 1 ENST00000245620.9:c.603A>G p.Thr201= p.T201= ENST00000245620 201 acA/acG 0 +LILRB4 UCSF GRCh37 19 55175893 55175893 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 45 70 0 ENST00000391736.1:c.612C>T p.Tyr204= p.Y204= ENST00000391736 NM_001278430.2 204 taC/taT 0 +LIMCH1 UCSF GRCh37 4 41648199 41648199 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 51 62 0 ENST00000313860.7:c.1158G>A p.Glu386= p.E386= ENST00000313860 NM_014988.2 386 gaG/gaA 0 +LINGO2 UCSF GRCh37 9 27948893 27948893 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 46 82 0 ENST00000379992.2:c.1777G>A p.Gly593Arg p.G593R ENST00000379992 NM_152570.2 593 Ggg/Agg 0 +LINS UCSF GRCh37 15 101114038 101114038 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 44 142 0 ENST00000314742.8:c.1040C>T p.Ser347Leu p.S347L ENST00000314742 NM_001040616.2 347 tCg/tTg 0 +LMBRD2 UCSF GRCh37 5 36143394 36143394 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 33 40 0 ENST00000296603.4:c.58C>T p.Leu20= p.L20= ENST00000296603 NM_001007527.1 20 Ctg/Ttg 0 +LMLN UCSF GRCh37 3 197748316 197748316 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 26 122 0 ENST00000420910.2:c.1477-1G>A p.X493_splice ENST00000420910 NM_001136049.2 0 +LMTK2 UCSF GRCh37 7 97821211 97821211 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 36 57 0 ENST00000297293.5:c.1434G>A p.Trp478Ter p.W478* ENST00000297293 NM_014916.3 478 tgG/tgA 0 +LOC100130357 UCSF GRCh37 6 13281226 13281226 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 34 58 0 ENST00000606150.1:n.606C>T *202* ENST00000606150 0 +LOC100653515 UCSF GRCh37 17 76887469 76887469 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 61 75 0 ENST00000322630.2:c.1117C>T p.Pro373Ser p.P373S ENST00000322630 NM_001243540.1 373 Cct/Tct 0 +LOC81691 UCSF GRCh37 16 20837259 20837259 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 32 70 0 ENST00000261377.6:c.810C>T p.Asp270= p.D270= ENST00000261377 NM_030941.2 270 gaC/gaT 0 +LOXL1 UCSF GRCh37 15 74239441 74239441 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 22 51 0 ENST00000261921.7:c.1383C>T p.Tyr461= p.Y461= ENST00000261921 NM_005576.2 461 taC/taT 0 +LPHN1 UCSF GRCh37 19 14271099 14271099 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 23 17 0 ENST00000340736.6:c.1640G>A p.Gly547Glu p.G547E ENST00000340736 NM_001008701.2 547 gGg/gAg 0 +LPP UCSF GRCh37 3 188327481 188327481 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 43 83 0 ENST00000312675.4:c.962G>A p.Gly321Asp p.G321D ENST00000312675 NM_005578.3 321 gGt/gAt 0 +LRIG3 UCSF GRCh37 12 59271268 59271268 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 24 56 0 ENST00000320743.3:c.2450G>A p.Cys817Tyr p.C817Y ENST00000320743 NM_153377.4 817 tGc/tAc 0 +LRP1 UCSF GRCh37 12 57599204 57599204 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 37 22 0 ENST00000243077.3:c.11406G>A p.Glu3802= p.E3802= ENST00000243077 NM_002332.2 3802 gaG/gaA 0 +LRP1B UCSF GRCh37 2 141115574 141115574 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 43 72 0 ENST00000389484.3:c.11369G>A p.Gly3790Asp p.G3790D ENST00000389484 NM_018557.2 3790 gGt/gAt 0 +LRP2 UCSF GRCh37 2 170136105 170136105 + missense_variant,splice_region_variant Missense_Mutation SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 24 34 0 ENST00000263816.3:c.1342G>T p.Val448Phe p.V448F ENST00000263816 NM_004525.2 448 Gtt/Ttt 0 +LRRC16B UCSF GRCh37 14 24531705 24531705 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 111 80 105 0 ENST00000342740.5:c.2497G>A p.Val833Ile p.V833I ENST00000342740 NM_138360.3 833 Gtc/Atc 0 +LRRC37A3 UCSF GRCh37 17 62856791 62856791 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 151 100 141 0 ENST00000584306.1:c.3473G>A p.Gly1158Asp p.G1158D ENST00000584306 NM_199340.2 1158 gGc/gAc 0 +LRRC37B UCSF GRCh37 17 30374838 30374838 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 177 107 160 0 ENST00000341671.7:c.2301G>A p.Arg767= p.R767= ENST00000341671 NM_052888.2 767 cgG/cgA 0 +LRRC48 UCSF GRCh37 17 17907751 17907751 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 43 71 0 ENST00000313838.8:c.1074C>T p.Ile358= p.I358= ENST00000313838 NM_001130090.1 358 atC/atT 0 +LRRC4C UCSF GRCh37 11 40136757 40136757 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 52 100 0 ENST00000278198.2:c.1086C>T p.Asp362= p.D362= ENST00000278198 362 gaC/gaT 0 +LRRC59 UCSF GRCh37 17 48474579 48474579 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 41 22 0 ENST00000225972.7:c.100G>A p.Glu34Lys p.E34K ENST00000225972 NM_018509.3 34 Gag/Aag 0 +LRRC61 UCSF GRCh37 7 150034385 150034385 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 25 31 0 ENST00000359623.4:c.435C>T p.Ser145= p.S145= ENST00000359623 NM_001142928.1 145 tcC/tcT 0 +LRRC7 UCSF GRCh37 1 70541956 70541956 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 33 68 0 ENST00000035383.5:c.4313G>A p.Arg1438Lys p.R1438K ENST00000035383 NM_020794.2 1438 aGg/aAg 0 +LRRC71 UCSF GRCh37 1 156899150 156899150 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 25 53 0 ENST00000337428.7:c.1075G>A p.Val359Met p.V359M ENST00000337428 NM_144702.2 359 Gtg/Atg 0 +LRRC8E UCSF GRCh37 19 7964090 7964090 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 33 35 0 ENST00000306708.6:c.683G>A p.Gly228Asp p.G228D ENST00000306708 NM_025061.4 228 gGt/gAt 0 +LRRFIP1 UCSF GRCh37 2 238671627 238671627 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 35 103 0 ENST00000392000.4:c.1271G>A p.Gly424Glu p.G424E ENST00000392000 NM_001137552.1 424 gGa/gAa 0 +LRRN4CL UCSF GRCh37 11 62455781 62455781 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 7 8 0 ENST00000317449.4:c.200G>A p.Gly67Glu p.G67E ENST00000317449 NM_203422.3 67 gGg/gAg 0 +LRTM1 UCSF GRCh37 3 54958759 54958759 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 29 74 0 ENST00000273286.5:c.491C>T p.Ala164Val p.A164V ENST00000273286 NM_020678.2 164 gCg/gTg 0 +LSM12 UCSF GRCh37 17 42141194 42141194 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 19 45 0 ENST00000591247.1:c.233C>T p.Pro78Leu p.P78L ENST00000591247 NM_152344.3 78 cCc/cTc 0 +LSR UCSF GRCh37 19 35739826 35739826 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 36 25 0 ENST00000361790.3:c.45G>A p.Gly15= p.G15= ENST00000361790 NM_205834.3 15 ggG/ggA 0 +LTBP1 UCSF GRCh37 2 33623560 33623560 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 33 68 0 ENST00000404816.2:c.5114G>A p.Cys1705Tyr p.C1705Y ENST00000404816 1705 tGc/tAc 0 +LUZP4 UCSF GRCh37 X 114537919 114537919 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 84 105 0 ENST00000371920.3:c.278C>T p.Ser93Phe p.S93F ENST00000371920 NM_016383.3 93 tCc/tTc 0 +LY6D UCSF GRCh37 8 143866676 143866676 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 16 11 0 ENST00000301263.4:c.348C>T p.Ala116= p.A116= ENST00000301263 NM_003695.2 116 gcC/gcT 0 +LY6G6F UCSF GRCh37 6 31675728 31675728 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 30 77 0 ENST00000375832.4:c.463G>A p.Asp155Asn p.D155N ENST00000375832 NM_001003693.1 155 Gac/Aac 0 +LY75 UCSF GRCh37 2 160738710 160738710 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 65 110 0 ENST00000504764.1:c.1171G>A p.Ala391Thr p.A391T ENST00000504764 NM_001198759.1 391 Gcc/Acc 0 +LY9 UCSF GRCh37 1 160793410 160793410 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 51 71 0 ENST00000263285.6:c.1654G>A p.Val552Met p.V552M ENST00000263285 552 Gtg/Atg 0 +LY9 UCSF GRCh37 1 160784304 160784304 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 24 49 0 ENST00000263285.6:c.825G>A p.Arg275= p.R275= ENST00000263285 275 cgG/cgA 0 +LYZL1 UCSF GRCh37 10 29581576 29581576 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 34 79 0 ENST00000375500.3:c.406G>A p.Glu136Lys p.E136K ENST00000375500 NM_032517.4 136 Gag/Aag 0 +LZIC UCSF GRCh37 1 9995591 9995591 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 118 60 106 0 ENST00000377223.1:c.196G>A p.Gly66Arg p.G66R ENST00000377223 66 Gga/Aga 0 +LZTS2 UCSF GRCh37 10 102763808 102763808 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 23 28 0 ENST00000370220.1:c.953C>T p.Pro318Leu p.P318L ENST00000370220 318 cCt/cTt 0 +MACF1 UCSF GRCh37 1 39823224 39823224 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 33 64 0 ENST00000545844.1:c.5416G>A p.Glu1806Lys p.E1806K ENST00000545844 1806 Gaa/Aaa 0 +MACF1 UCSF GRCh37 1 39905119 39905119 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 25 66 0 ENST00000545844.1:c.12217G>A p.Glu4073Lys p.E4073K ENST00000545844 4073 Gaa/Aaa 0 +MACF1 UCSF GRCh37 1 39916782 39916782 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 37 70 0 ENST00000545844.1:c.14140G>A p.Ala4714Thr p.A4714T ENST00000545844 4714 Gca/Aca 0 +MAD1L1 UCSF GRCh37 7 2054237 2054237 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 12 12 0 ENST00000406869.1:c.1259G>A p.Ser420Asn p.S420N ENST00000406869 420 aGc/aAc 0 +MAG UCSF GRCh37 19 35786832 35786832 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 163 108 91 0 ENST00000392213.3:c.363G>A p.Leu121= p.L121= ENST00000392213 NM_002361.3 121 ctG/ctA 0 +MAGEE2 UCSF GRCh37 X 75004566 75004566 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 22 31 0 ENST00000373359.2:c.321G>A p.Gly107= p.G107= ENST00000373359 NM_138703.4 107 ggG/ggA 0 +MAGI2 UCSF GRCh37 7 78131015 78131015 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 120 29 61 0 ENST00000354212.4:c.844G>A p.Glu282Lys p.E282K ENST00000354212 NM_012301.3 282 Gag/Aag 0 +MALL UCSF GRCh37 2 110849244 110849244 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 20 93 0 ENST00000272462.2:c.209C>T p.Ser70Phe p.S70F ENST00000272462 NM_005434.4 70 tCc/tTc 0 +MALL UCSF GRCh37 2 110849239 110849239 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 83 19 90 0 ENST00000272462.2:c.214A>C p.Met72Leu p.M72L ENST00000272462 NM_005434.4 72 Atg/Ctg 0 +MAN1A1 UCSF GRCh37 6 119623264 119623264 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 19 39 0 ENST00000368468.3:c.705C>T p.Asn235= p.N235= ENST00000368468 NM_005907.3 235 aaC/aaT 0 +MAN2C1 UCSF GRCh37 15 75648258 75648258 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 27 19 0 ENST00000565683.1:c.3163C>T p.Pro1055Ser p.P1055S ENST00000565683 NM_001256494.1 1055 Ccg/Tcg 0 +MANSC1 UCSF GRCh37 12 12483769 12483769 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 32 91 0 ENST00000535902.1:c.488C>T p.Pro163Leu p.P163L ENST00000535902 163 cCc/cTc 0 +MAP1A UCSF GRCh37 15 43822285 43822285 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 48 77 0 ENST00000300231.5:c.8275C>T p.His2759Tyr p.H2759Y ENST00000300231 2759 Cat/Tat 0 +MAP1A UCSF GRCh37 15 43821976 43821976 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 36 27 0 ENST00000300231.5:c.8164G>A p.Val2722Ile p.V2722I ENST00000300231 2722 Gtc/Atc 0 +MAP2 UCSF GRCh37 2 210559366 210559366 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 137 71 123 0 ENST00000360351.4:c.2472A>G p.Ala824= p.A824= ENST00000360351 NM_002374.3 824 gcA/gcG 0 +MAP3K12 UCSF GRCh37 12 53881086 53881086 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 42 39 0 ENST00000547035.1:c.90C>T p.Asp30= p.D30= ENST00000547035 30 gaC/gaT 0 +MAP3K13 UCSF GRCh37 3 185161342 185161342 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 29 89 0 ENST00000265026.3:c.769G>A p.Val257Ile p.V257I ENST00000265026 NM_004721.4 257 Gta/Ata 0 +MAP3K15 UCSF GRCh37 X 19478195 19478195 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 63 122 0 ENST00000338883.4:c.796G>A p.Glu266Lys p.E266K ENST00000338883 NM_001001671.3 266 Gag/Aag 0 +MAP3K2 UCSF GRCh37 2 128075877 128075877 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 74 118 0 ENST00000409947.1:c.1062C>T p.Thr354= p.T354= ENST00000409947 354 acC/acT 0 +MAP3K6 UCSF GRCh37 1 27690766 27690766 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 31 29 0 ENST00000493901.1:c.624G>A p.Gly208= p.G208= ENST00000493901 NM_004672.3 208 ggG/ggA 0 +MAP4K1 UCSF GRCh37 19 39086617 39086617 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 56 66 0 ENST00000591517.1:c.2141C>T p.Thr714Ile p.T714I ENST00000591517 NM_007181.4 714 aCc/aTc 0 +MAP4K4 UCSF GRCh37 2 102460666 102460666 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 45 43 0 ENST00000347699.4:c.1126C>T p.Leu376= p.L376= ENST00000347699 NM_145687.3 376 Cta/Tta 0 +MARCH7 UCSF GRCh37 2 160615737 160615737 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 43 62 0 ENST00000259050.4:c.1784G>A p.Gly595Asp p.G595D ENST00000259050 NM_022826.2 595 gGt/gAt 0 +MARK2 UCSF GRCh37 11 63670230 63670230 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 21 16 0 ENST00000402010.2:c.1392G>A p.Lys464= p.K464= ENST00000402010 NM_001039469.2 464 aaG/aaA 0 +MAST3 UCSF GRCh37 19 18232506 18232506 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 104 83 55 0 ENST00000262811.6:c.83G>A p.Gly28Glu p.G28E ENST00000262811 NM_015016.1 28 gGg/gAg 0 +MAT2A UCSF GRCh37 2 85769819 85769819 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 38 48 0 ENST00000306434.3:c.900G>A p.Trp300Ter p.W300* ENST00000306434 NM_005911.5 300 tgG/tgA 0 +MATN4 UCSF GRCh37 20 43932943 43932943 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 37 9 0 ENST00000537548.1:c.568G>A p.Asp190Asn p.D190N ENST00000537548 NM_003833.4 190 Gac/Aac 0 +MATR3 UCSF GRCh37 5 138643547 138643547 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 47 74 0 ENST00000394805.3:c.443G>A p.Arg148Lys p.R148K ENST00000394805 NM_001194955.1 148 aGg/aAg 0 +MAX UCSF GRCh37 14 65472892 65472898 + intron_variant Intron INS GCCACCA GCCACCA TGCCCCCT NOVEL P05_Rec Untested WXS Illumina HiSeq 6 0 ENST00000246166.2:c.209+1861_209+1867delinsTGCCCCCT *70* ENST00000246166 NM_002028.3 0 +MBD6 UCSF GRCh37 12 57919877 57919877 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 40 55 0 ENST00000355673.3:c.1126C>T p.Leu376= p.L376= ENST00000355673 NM_052897.3 376 Cta/Tta 0 +MBIP UCSF GRCh37 14 36783783 36783783 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 21 11 0 ENST00000416007.4:c.506G>A p.Arg169Lys p.R169K ENST00000416007 NM_016586.2 169 aGa/aAa 0 +MCCC2 UCSF GRCh37 5 70945963 70945963 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 68 110 0 ENST00000340941.6:c.1441G>A p.Val481Met p.V481M ENST00000340941 NM_022132.4 481 Gtg/Atg 0 +MCM2 UCSF GRCh37 3 127338011 127338011 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 22 33 0 ENST00000265056.7:c.2155G>A p.Val719Ile p.V719I ENST00000265056 NM_004526.3 719 Gtc/Atc 0 +MCOLN1 UCSF GRCh37 19 7591679 7591679 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 32 31 0 ENST00000264079.6:c.438G>A p.Arg146= p.R146= ENST00000264079 NM_020533.2 146 cgG/cgA 0 +MDC1 UCSF GRCh37 6 30680044 30680044 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 37 62 0 ENST00000376406.3:c.1675C>T p.Pro559Ser p.P559S ENST00000376406 NM_014641.2 559 Cca/Tca 0 +MDFIC UCSF GRCh37 7 114655875 114655875 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 242 63 165 0 ENST00000257724.3:c.954G>A p.Gly318= p.G318= ENST00000257724 318 ggG/ggA 0 +MDGA1 UCSF GRCh37 6 37614108 37614108 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 18 27 0 ENST00000434837.3:c.2090G>A p.Arg697His p.R697H ENST00000434837 NM_153487.3 697 cGt/cAt 0 +MDGA1 UCSF GRCh37 6 37619918 37619918 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 29 40 0 ENST00000434837.3:c.1181C>T p.Pro394Leu p.P394L ENST00000434837 NM_153487.3 394 cCc/cTc 0 +MDM4 UCSF GRCh37 1 204511996 204511996 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 80 47 90 0 ENST00000367182.3:c.596C>T p.Pro199Leu p.P199L ENST00000367182 NM_001278516.1 199 cCt/cTt 0 +MED1 UCSF GRCh37 17 37566483 37566483 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 46 118 0 ENST00000300651.6:c.1991G>A p.Ser664Asn p.S664N ENST00000300651 NM_004774.3 664 aGc/aAc 0 +MED22 UCSF GRCh37 9 136211168 136211168 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 119 62 59 0 ENST00000491289.1:c.225G>A p.Leu75= p.L75= ENST00000491289 75 ctG/ctA 0 +MED23 UCSF GRCh37 6 131917238 131917238 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 64 116 0 ENST00000368068.3:c.2844G>A p.Gln948= p.Q948= ENST00000368068 NM_004830.3 948 caG/caA 0 +MED23 UCSF GRCh37 6 131949151 131949151 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 36 50 0 ENST00000368068.3:c.39G>A p.Val13= p.V13= ENST00000368068 NM_004830.3 13 gtG/gtA 0 +MED24 UCSF GRCh37 17 38182450 38182450 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.00098 P05_Rec Untested WXS Illumina HiSeq 119 68 73 0 ENST00000394128.2:c.1944G>A p.Gly648= p.G648= ENST00000394128 NM_014815.3 648 ggG/ggA 0 +MEF2B UCSF GRCh37 19 19257881 19257881 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 6 8 0 ENST00000162023.5:c.505C>T p.Pro169Ser p.P169S ENST00000162023 169 Ccc/Tcc 0 +MEIG1 UCSF GRCh37 10 15014527 15014527 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 20 87 0 ENST00000407572.1:c.154G>A p.Glu52Lys p.E52K ENST00000407572 NM_001080836.2 52 Gag/Aag 0 +MEIS2 UCSF GRCh37 15 37184661 37184661 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 71 108 0 ENST00000561208.1:c.1148-1G>A p.X383_splice ENST00000561208 0 +METAP2 UCSF GRCh37 12 95887890 95887890 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 36 59 0 ENST00000323666.5:c.487G>A p.Glu163Lys p.E163K ENST00000323666 NM_006838.3 163 Gaa/Aaa 0 +METTL21D UCSF GRCh37 14 50582895 50582895 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 81 99 0 ENST00000395860.2:c.269C>T p.Ala90Val p.A90V ENST00000395860 NM_024558.2 90 gCt/gTt 0 +MFAP4 UCSF GRCh37 17 19287934 19287934 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 20 35 0 ENST00000395592.2:c.681C>T p.Ser227= p.S227= ENST00000395592 NM_001198695.1 227 tcC/tcT 0 +MFSD11 UCSF GRCh37 17 74771103 74771103 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 159 67 133 0 ENST00000588460.1:c.899G>A p.Ser300Asn p.S300N ENST00000588460 NM_001242534.1 300 aGc/aAc 0 +MGAM UCSF GRCh37 7 141738364 141738364 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 9 34 0 ENST00000549489.2:c.2265C>T p.His755= p.H755= ENST00000549489 NM_004668.2 755 caC/caT 0 +MGAT2 UCSF GRCh37 14 50088200 50088200 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 26 32 0 ENST00000305386.2:c.214G>A p.Ala72Thr p.A72T ENST00000305386 NM_002408.3 72 Gcg/Acg 0 +MGAT3 UCSF GRCh37 22 39884476 39884476 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 78 22 0 ENST00000341184.6:c.1124G>A p.Gly375Glu p.G375E ENST00000341184 NM_002409.4 375 gGg/gAg 0 +MGRN1 UCSF GRCh37 16 4731676 4731676 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 57 27 0 ENST00000262370.7:c.1257C>T p.Ile419= p.I419= ENST00000262370 NM_015246.3 419 atC/atT 0 +MIA2 4253 UCSF GRCh37 14 39703402 39703402 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 145 53 157 0 ENST00000280082.3:c.84C>T p.Asp28= p.D28= ENST00000280082 NM_054024.3 28 gaC/gaT 0 +MIB1 UCSF GRCh37 18 19378066 19378066 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 44 88 0 ENST00000261537.6:c.1114G>A p.Val372Ile p.V372I ENST00000261537 NM_020774.3 372 Gta/Ata 0 +MILR1 UCSF GRCh37 17 62462747 62462747 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 41 51 0 ENST00000605096.1:c.184C>T p.Pro62Leu p.P62L ENST00000605096 NM_001085423.1 62 cCc/cTc 0 +MIXL1 UCSF GRCh37 1 226413277 226413277 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 53 80 0 ENST00000366810.5:c.463C>T p.Pro155Ser p.P155S ENST00000366810 155 Ccg/Tcg 0 +MKNK1 UCSF GRCh37 1 47048942 47048942 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 39 88 0 ENST00000371946.4:c.94C>T p.Arg32Trp p.R32W ENST00000371946 NM_003684.5 32 Cgg/Tgg 0 +MKS1 UCSF GRCh37 17 56294080 56294080 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 15 42 0 ENST00000393119.2:c.208G>A p.Glu70Lys p.E70K ENST00000393119 NM_017777.3 70 Gaa/Aaa 0 +MLL2 UCSF GRCh37 12 49424208 49424208 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 6 10 12 0 ENST00000301067.7:c.13854C>T p.Asn4618= p.N4618= ENST00000301067 NM_003482.3 4618 aaC/aaT 0 +MLL2 UCSF GRCh37 12 49432034 49432034 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 58 72 0 ENST00000301067.7:c.9105C>T p.Asp3035= p.D3035= ENST00000301067 NM_003482.3 3035 gaC/gaT 0 +MLL3 UCSF GRCh37 7 151835881 151835881 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 250 45 132 0 ENST00000262189.6:c.14643G>A p.Glu4881= p.E4881= ENST00000262189 NM_170606.2 4881 gaG/gaA 0 +MLLT4 UCSF GRCh37 6 168319538 168319538 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 21 44 0 ENST00000392108.3:c.2812G>A p.Asp938Asn p.D938N ENST00000392108 NM_001040000.2 938 Gat/Aat 0 +MLLT6 UCSF GRCh37 17 36880878 36880878 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 14 15 0 ENST00000325718.7:c.2889C>T p.His963= p.H963= ENST00000325718 NM_005937.3 963 caC/caT 0 +MLNR UCSF GRCh37 13 49795343 49795343 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 16 10 0 ENST00000218721.1:c.870G>A p.Glu290= p.E290= ENST00000218721 NM_001507.1 290 gaG/gaA 0 +MLYCD UCSF GRCh37 16 83948616 83948616 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 344 144 159 0 ENST00000262430.4:c.1004C>T p.Thr335Ile p.T335I ENST00000262430 NM_012213.2 335 aCc/aTc 0 +MMAA UCSF GRCh37 4 146572288 146572288 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 31 44 0 ENST00000281317.5:c.808G>A p.Asp270Asn p.D270N ENST00000281317 NM_172250.2 270 Gat/Aat 0 +MMAA UCSF GRCh37 4 146575229 146575229 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 55 112 0 ENST00000281317.5:c.903G>A p.Arg301= p.R301= ENST00000281317 NM_172250.2 301 agG/agA 0 +MMP14 UCSF GRCh37 14 23311145 23311145 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 52 69 0 ENST00000311852.6:c.281G>A p.Gly94Asp p.G94D ENST00000311852 NM_004995.3 94 gGt/gAt 0 +MMP15 UCSF GRCh37 16 58079067 58079067 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 18 14 0 ENST00000219271.3:c.1727C>T p.Pro576Leu p.P576L ENST00000219271 NM_002428.2 576 cCc/cTc 0 +MMP16 UCSF GRCh37 8 89339416 89339416 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 60 74 0 ENST00000286614.6:c.20G>A p.Ser7Asn p.S7N ENST00000286614 NM_005941.4 7 aGc/aAc 0 +MMP17 UCSF GRCh37 12 132329946 132329946 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 48 18 8 0 ENST00000360564.1:c.1156G>A p.Asp386Asn p.D386N ENST00000360564 NM_016155.4 386 Gac/Aac 0 +MMP24 UCSF GRCh37 20 33839763 33839763 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 184 57 181 0 ENST00000246186.6:c.451C>T p.Arg151Trp p.R151W ENST00000246186 NM_006690.3 151 Cgg/Tgg 0 +MN1 UCSF GRCh37 22 28194159 28194159 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 55 32 16 0 ENST00000302326.4:c.2373C>T p.Phe791= p.F791= ENST00000302326 NM_002430.2 791 ttC/ttT 0 +MOBP UCSF GRCh37 3 39543657 39543657 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 158 73 51 0 ENST00000383754.3:c.97C>T p.Leu33Phe p.L33F ENST00000383754 NM_182935.3 33 Ctc/Ttc 0 +MOV10 UCSF GRCh37 1 113235546 113235546 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 12 7 15 0 ENST00000413052.2:c.1135C>T p.Leu379= p.L379= ENST00000413052 NM_001130079.1 379 Ctg/Ttg 0 +MPDZ UCSF GRCh37 9 13183527 13183527 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 132 76 107 0 ENST00000541718.1:c.2539C>T p.Pro847Ser p.P847S ENST00000541718 NM_001261407.1 847 Cct/Tct 0 +MPP1 UCSF GRCh37 X 154018261 154018261 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 20 43 0 ENST00000369534.3:c.448C>T p.Pro150Ser p.P150S ENST00000369534 NM_001166461.1 150 Ccc/Tcc 0 +MPP3 UCSF GRCh37 17 41891415 41891415 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 76 106 0 ENST00000398389.4:c.1219G>A p.Ala407Thr p.A407T ENST00000398389 NM_001932.4 407 Gct/Act 0 +MPP3 UCSF GRCh37 17 41901303 41901303 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 27 43 0 ENST00000398389.4:c.680G>A p.Ser227Asn p.S227N ENST00000398389 NM_001932.4 227 aGc/aAc 0 +MRC2 UCSF GRCh37 17 60741999 60741999 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 47 47 0 ENST00000303375.5:c.209C>T p.Thr70Ile p.T70I ENST00000303375 NM_006039.4 70 aCc/aTc 0 +MRPL24 UCSF GRCh37 1 156708209 156708209 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 125 99 168 0 ENST00000361531.2:c.205G>A p.Asp69Asn p.D69N ENST00000361531 69 Gat/Aat 0 +MRPS17 UCSF GRCh37 7 56022616 56022616 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 278 93 183 0 ENST00000285298.4:c.138G>A p.Arg46= p.R46= ENST00000285298 NM_015969.2 46 cgG/cgA 0 +MRPS21 UCSF GRCh37 1 150266816 150266816 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 21 47 0 ENST00000369084.5:c.30G>A p.Arg10= p.R10= ENST00000369084 NM_018997.3 10 agG/agA 0 +MRPS24 UCSF GRCh37 7 43906315 43906315 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 23 76 0 ENST00000317534.5:c.487G>A p.Val163Met p.V163M ENST00000317534 NM_032014.2 163 Gtg/Atg 0 +MSH6 UCSF GRCh37 2 48030615 48030615 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 20 38 57 0 ENST00000234420.5:c.3229C>T p.Pro1077Ser p.P1077S ENST00000234420 NM_000179.2 1077 Cca/Tca 0 +MSL2 UCSF GRCh37 3 135871035 135871035 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 62 22 42 0 ENST00000309993.2:c.688G>A p.Asp230Asn p.D230N ENST00000309993 NM_018133.3 230 Gat/Aat 0 +MSLNL UCSF GRCh37 16 823159 823159 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 42 28 0 ENST00000293892.3:c.2109C>T p.Cys703= p.C703= ENST00000293892 703 tgC/tgT 0 +MST1R UCSF GRCh37 3 49928724 49928724 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 19 34 0 ENST00000296474.3:c.3550G>A p.Asp1184Asn p.D1184N ENST00000296474 NM_002447.2 1184 Gac/Aac 0 +MT1A UCSF GRCh37 16 56673188 56673188 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 133 23 81 0 ENST00000290705.8:c.41C>T p.Thr14Ile p.T14I ENST00000290705 NM_005946.2 14 aCc/aTc 0 +MTCH1 UCSF GRCh37 6 36940490 36940490 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 3 15 0 ENST00000373616.5:c.844G>A p.Val282Met p.V282M ENST00000373616 NM_014341.2 282 Gtg/Atg 0 +MTERFD2 UCSF GRCh37 2 242038848 242038848 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 40 82 0 ENST00000391980.2:c.483G>A p.Lys161= p.K161= ENST00000391980 NM_182501.3 161 aaG/aaA 0 +MTHFD1 UCSF GRCh37 14 64905841 64905841 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 16 41 0 ENST00000216605.8:c.1625G>A p.Arg542Lys p.R542K ENST00000216605 NM_005956.3 542 aGg/aAg 0 +MTL5 UCSF GRCh37 11 68480777 68480777 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 132 109 0 ENST00000255087.5:c.1119G>A p.Arg373= p.R373= ENST00000255087 NM_004923.3 373 agG/agA 0 +MTMR8 UCSF GRCh37 X 63574685 63574685 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 32 64 0 ENST00000374852.3:c.440C>T p.Thr147Ile p.T147I ENST00000374852 NM_017677.3 147 aCc/aTc 0 +MTMR8 UCSF GRCh37 X 63579408 63579408 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 46 53 0 ENST00000374852.3:c.25-1G>A p.X9_splice ENST00000374852 NM_017677.3 0 +MTNR1A UCSF GRCh37 4 187455161 187455161 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 73 107 0 ENST00000307161.5:c.735C>T p.Val245= p.V245= ENST00000307161 NM_005958.3 245 gtC/gtT 0 +MTPAP UCSF GRCh37 10 30625909 30625909 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 132 61 101 0 ENST00000263063.4:c.603G>A p.Glu201= p.E201= ENST00000263063 NM_018109.3 201 gaG/gaA 0 +MTR UCSF GRCh37 1 236998947 236998947 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 104 62 133 0 ENST00000366577.5:c.1289G>A p.Arg430Lys p.R430K ENST00000366577 NM_000254.2 430 aGa/aAa 0 +MTUS1 UCSF GRCh37 8 17612062 17612062 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 52 73 0 ENST00000262102.6:c.1255G>A p.Val419Ile p.V419I ENST00000262102 NM_001001924.2 419 Gtc/Atc 0 +MUC15 UCSF GRCh37 11 26584798 26584798 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 48 76 0 ENST00000436318.2:c.790G>A p.Gly264Arg p.G264R ENST00000436318 264 Gga/Aga 0 +MUC16 UCSF GRCh37 19 9027261 9027261 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 22 29 0 ENST00000397910.4:c.36625G>A p.Asp12209Asn p.D12209N ENST00000397910 NM_024690.2 12209 Gat/Aat 0 +MUC16 UCSF GRCh37 19 9047729 9047729 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 58 81 0 ENST00000397910.4:c.33902C>T p.Ala11301Val p.A11301V ENST00000397910 NM_024690.2 11301 gCa/gTa 0 +MUC16 UCSF GRCh37 19 9067981 9067981 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 108 51 127 0 ENST00000397910.4:c.19465C>T p.Leu6489Phe p.L6489F ENST00000397910 NM_024690.2 6489 Ctt/Ttt 0 +MUC16 UCSF GRCh37 19 9073785 9073785 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 90 123 0 ENST00000397910.4:c.13661C>T p.Thr4554Ile p.T4554I ENST00000397910 NM_024690.2 4554 aCt/aTt 0 +MUC16 UCSF GRCh37 19 9084076 9084076 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 135 78 136 0 ENST00000397910.4:c.7739C>T p.Thr2580Ile p.T2580I ENST00000397910 NM_024690.2 2580 aCa/aTa 0 +MUC16 UCSF GRCh37 19 9084824 9084824 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 65 140 0 ENST00000397910.4:c.6991C>T p.Leu2331Phe p.L2331F ENST00000397910 NM_024690.2 2331 Ctc/Ttc 0 +MUC17 UCSF GRCh37 7 100677195 100677195 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 357 101 228 0 ENST00000306151.4:c.2498C>T p.Ser833Phe p.S833F ENST00000306151 NM_001040105.1 833 tCc/tTc 0 +MUC21 UCSF GRCh37 6 30955956 30955956 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 13 35 0 ENST00000376296.3:c.1686G>A p.Arg562= p.R562= ENST00000376296 NM_001010909.2 562 agG/agA 0 +MUC4 UCSF GRCh37 3 195507907 195507907 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 677 83 477 0 ENST00000463781.3:c.10544C>T p.Thr3515Ile p.T3515I ENST00000463781 NM_018406.6 3515 aCc/aTc 0 +MUC4 UCSF GRCh37 3 195518202 195518202 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 132 111 239 0 ENST00000463781.3:c.249G>A p.Glu83= p.E83= ENST00000463781 NM_018406.6 83 gaG/gaA 0 +MUC4 UCSF GRCh37 3 195510396 195510396 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 60 10 97 1 ENST00000463781.3:c.8055T>G p.His2685Gln p.H2685Q ENST00000463781 NM_018406.6 2685 caT/caG 0 +MUC4 UCSF GRCh37 3 195508523 195508523 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 9 35 1 ENST00000463781.3:c.9928G>A p.Ala3310Thr p.A3310T ENST00000463781 NM_018406.6 3310 Gcc/Acc 0 +MUC5B UCSF GRCh37 11 1250478 1250478 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 10 10 8 0 ENST00000529681.1:c.1055C>T p.Ala352Val p.A352V ENST00000529681 NM_002458.2 352 gCg/gTg 0 +MUC5B UCSF GRCh37 11 1266696 1266696 + synonymous_variant Silent SNP A A C 1000g2011may_all_0.1446,snp132_rs4046509 P05_Rec Untested WXS Illumina HiSeq 22 3 37 0 ENST00000529681.1:c.8586A>C p.Pro2862= p.P2862= ENST00000529681 NM_002458.2 2862 ccA/ccC 0 +MUC6 UCSF GRCh37 11 1017480 1017480 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 530 121 459 0 ENST00000421673.2:c.5321C>T p.Thr1774Ile p.T1774I ENST00000421673 NM_005961.2 1774 aCc/aTc 0 +MUC6 UCSF GRCh37 11 1027375 1027375 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 71 69 0 ENST00000421673.2:c.2124C>T p.Tyr708= p.Y708= ENST00000421673 NM_005961.2 708 taC/taT 0 +MYC UCSF GRCh37 8 128750682 128750682 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 50 17 0 ENST00000377970.2:c.219C>T p.Thr73= p.T73= ENST00000377970 NM_002467.4 73 acC/acT 0 +MYH10 UCSF GRCh37 17 8379127 8379127 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 61 95 0 ENST00000360416.3:c.6019G>A p.Glu2007Lys p.E2007K ENST00000360416 NM_001256012.1 2007 Gag/Aag 0 +MYH10 UCSF GRCh37 17 8416891 8416891 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 37 66 0 ENST00000360416.3:c.2710G>A p.Gly904Arg p.G904R ENST00000360416 NM_001256012.1 904 Gga/Aga 0 +MYH11 UCSF GRCh37 16 15826454 15826454 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 56 91 0 ENST00000396324.3:c.3639G>A p.Glu1213= p.E1213= ENST00000396324 NM_001040114.1 1213 gaG/gaA 0 +MYH14 UCSF GRCh37 19 50764856 50764856 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 17 14 0 ENST00000601313.1:c.2549C>T p.Ser850Phe p.S850F ENST00000601313 NM_001145809.1 850 tCc/tTc 0 +MYH14 UCSF GRCh37 19 50783378 50783378 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 26 24 0 ENST00000601313.1:c.4117G>A p.Ala1373Thr p.A1373T ENST00000601313 NM_001145809.1 1373 Gcc/Acc 0 +MYH2 UCSF GRCh37 17 10436690 10436690 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 36 98 0 ENST00000245503.5:c.2353G>A p.Asp785Asn p.D785N ENST00000245503 NM_017534.5 785 Gac/Aac 0 +MYO18A UCSF GRCh37 17 27434097 27434097 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 40 43 0 ENST00000527372.1:c.3441+1G>A p.X1147_splice ENST00000527372 NM_078471.3 0 +MYO18B UCSF GRCh37 22 26239836 26239836 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 43 57 0 ENST00000335473.7:c.3343C>T p.Pro1115Ser p.P1115S ENST00000335473 NM_032608.5 1115 Ccc/Tcc 0 +MYO18B UCSF GRCh37 22 26422815 26422815 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 36 25 0 ENST00000335473.7:c.6875G>A p.Gly2292Asp p.G2292D ENST00000335473 NM_032608.5 2292 gGc/gAc 0 +MYO1D UCSF GRCh37 17 31039119 31039119 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 114 77 109 0 ENST00000318217.5:c.2008G>A p.Asp670Asn p.D670N ENST00000318217 NM_015194.1 670 Gat/Aat 0 +MYO1E UCSF GRCh37 15 59548493 59548493 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 11 45 0 ENST00000288235.4:c.322G>A p.Val108Ile p.V108I ENST00000288235 NM_004998.3 108 Gtc/Atc 0 +MYO1E UCSF GRCh37 15 59515337 59515337 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 37 79 0 ENST00000288235.4:c.831G>A p.Gln277= p.Q277= ENST00000288235 NM_004998.3 277 caG/caA 0 +MYO1H UCSF GRCh37 12 109874303 109874303 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 18 58 0 ENST00000310903.5:c.2103C>T p.Ile701= p.I701= ENST00000310903 701 atC/atT 0 +MYO5A UCSF GRCh37 15 52720755 52720755 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 47 104 0 ENST00000399231.3:c.150C>T p.Tyr50= p.Y50= ENST00000399231 NM_000259.3 50 taC/taT 0 +MYO5B UCSF GRCh37 18 47363930 47363930 + synonymous_variant Silent SNP A A G snp132_rs79271359 P05_Rec Untested WXS Illumina HiSeq 82 10 54 1 ENST00000285039.7:c.5095T>C p.Leu1699= p.L1699= ENST00000285039 NM_001080467.2 1699 Ttg/Ctg 0 +MYO5B UCSF GRCh37 18 47363931 47363931 + synonymous_variant Silent SNP G G C snp132_rs77840018 P05_Rec Untested WXS Illumina HiSeq 83 10 54 1 ENST00000285039.7:c.5094C>G p.Leu1698= p.L1698= ENST00000285039 NM_001080467.2 1698 ctC/ctG 0 +MYO7A UCSF GRCh37 11 76867778 76867778 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 165 28 105 0 ENST00000409709.3:c.543G>T p.Gln181His p.Q181H ENST00000409709 NM_000260.3 181 caG/caT 0 +MYO9B UCSF GRCh37 19 17305959 17305959 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 43 20 0 ENST00000595618.1:c.3723G>A p.Gly1241= p.G1241= ENST00000595618 NM_001130065.1 1241 ggG/ggA 0 +MYOC UCSF GRCh37 1 171621570 171621570 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 34 42 0 ENST00000037502.6:c.182G>A p.Cys61Tyr p.C61Y ENST00000037502 NM_000261.1 61 tGc/tAc 0 +MYOG UCSF GRCh37 1 203054970 203054970 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 58 38 0 ENST00000241651.4:c.120C>T p.Leu40= p.L40= ENST00000241651 NM_002479.5 40 ctC/ctT 0 +MYOM1 UCSF GRCh37 18 3071858 3071858 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 12 24 0 ENST00000356443.4:c.4738G>A p.Asp1580Asn p.D1580N ENST00000356443 NM_019856.1 1580 Gac/Aac 0 +MYOM1 UCSF GRCh37 18 3188757 3188757 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 31 68 0 ENST00000356443.4:c.760C>T p.Leu254= p.L254= ENST00000356443 NM_019856.1 254 Ctg/Ttg 0 +MYOM3 UCSF GRCh37 1 24398469 24398469 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 14 43 0 ENST00000374434.3:c.3003C>T p.Ile1001= p.I1001= ENST00000374434 NM_152372.3 1001 atC/atT 0 +NAA15 UCSF GRCh37 4 140262178 140262178 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 27 59 0 ENST00000296543.5:c.357C>T p.Asp119= p.D119= ENST00000296543 NM_057175.3 119 gaC/gaT 0 +NAA25 UCSF GRCh37 12 112528571 112528571 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 52 78 0 ENST00000261745.4:c.242C>T p.Ser81Leu p.S81L ENST00000261745 NM_024953.3 81 tCa/tTa 0 +NAA30 UCSF GRCh37 14 57858361 57858361 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 200 157 117 1 ENST00000556492.1:c.686G>A p.Arg229Lys p.R229K ENST00000556492 NM_001011713.2 229 aGa/aAa 0 +NAALADL1 UCSF GRCh37 11 64822020 64822020 + missense_variant Missense_Mutation SNP G G A snp132_rs35867135 P05_Rec Untested WXS Illumina HiSeq 25 19 17 0 ENST00000358658.3:c.794C>T p.Pro265Leu p.P265L ENST00000358658 NM_005468.2 265 cCc/cTc 0 +NAALADL1 UCSF GRCh37 11 64815162 64815162 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 8 8 0 ENST00000358658.3:c.1465C>T p.Arg489Trp p.R489W ENST00000358658 NM_005468.2 489 Cgg/Tgg 0 +NACC1 UCSF GRCh37 19 13246770 13246770 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 17 8 0 ENST00000292431.4:c.749G>A p.Gly250Glu p.G250E ENST00000292431 NM_052876.3 250 gGg/gAg 0 +NAGS UCSF GRCh37 17 42085896 42085896 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 154 100 130 0 ENST00000293404.3:c.1532C>T p.Ser511Phe p.S511F ENST00000293404 NM_153006.2 511 tCc/tTc 0 +NARF UCSF GRCh37 17 80422223 80422223 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 44 65 0 ENST00000309794.11:c.169G>A p.Asp57Asn p.D57N ENST00000309794 NM_031968.2 57 Gac/Aac 0 +NARFL UCSF GRCh37 16 784752 784752 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 54 45 0 ENST00000251588.2:c.559G>A p.Ala187Thr p.A187T ENST00000251588 NM_022493.1 187 Gcc/Acc 0 +NBPF3 UCSF GRCh37 1 21804669 21804669 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 201 128 274 0 ENST00000318249.5:c.1025C>T p.Pro342Leu p.P342L ENST00000318249 NM_032264.4 342 cCc/cTc 0 +NCAM1 UCSF GRCh37 11 113085228 113085228 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 40 97 0 ENST00000524665.1:c.1231G>A p.Glu411Lys p.E411K ENST00000524665 NM_000615.6 411 Gaa/Aaa 0 +NCAN UCSF GRCh37 19 19327790 19327790 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 52 78 0 ENST00000252575.6:c.28G>A p.Gly10Ser p.G10S ENST00000252575 NM_004386.2 10 Ggc/Agc 0 +NCAPH UCSF GRCh37 2 97026441 97026441 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 66 77 0 ENST00000240423.4:c.1580G>A p.Gly527Asp p.G527D ENST00000240423 NM_001281711.1 527 gGc/gAc 0 +NCOA1 UCSF GRCh37 2 24930252 24930252 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 45 73 0 ENST00000406961.1:c.1913C>T p.Thr638Ile p.T638I ENST00000406961 638 aCa/aTa 0 +NCOA5 UCSF GRCh37 20 44691394 44691394 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 43 73 0 ENST00000290231.6:c.1285C>T p.Gln429Ter p.Q429* ENST00000290231 NM_020967.2 429 Caa/Taa 0 +NCOR2 UCSF GRCh37 12 124848269 124848269 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 18 27 0 ENST00000405201.1:c.2884G>A p.Asp962Asn p.D962N ENST00000405201 962 Gac/Aac 0 +NCOR2 UCSF GRCh37 12 124819735 124819735 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 14 10 0 ENST00000405201.1:c.6357C>T p.Thr2119= p.T2119= ENST00000405201 2119 acC/acT 0 +NDNF UCSF GRCh37 4 121957629 121957629 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 73 83 0 ENST00000379692.4:c.1497C>T p.Asn499= p.N499= ENST00000379692 NM_024574.3 499 aaC/aaT 0 +NDUFB10 UCSF GRCh37 16 2011557 2011557 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 44 37 0 ENST00000268668.6:c.329G>A p.Arg110Lys p.R110K ENST00000268668 NM_004548.2 110 aGg/aAg 0 +NDUFS2 UCSF GRCh37 1 161173255 161173255 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 14 15 0 ENST00000367993.3:c.124G>A p.Glu42Lys p.E42K ENST00000367993 NM_004550.4 42 Gaa/Aaa 0 +NDUFV1 UCSF GRCh37 11 67378012 67378012 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 13 31 0 ENST00000322776.6:c.671G>T p.Arg224Leu p.R224L ENST00000322776 NM_001166102.1 224 cGc/cTc 0 +NEB UCSF GRCh37 2 152580850 152580850 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 45 77 0 ENST00000397345.3:c.536C>T p.Thr179Ile p.T179I ENST00000397345 NM_001164508.1 179 aCc/aTc 0 +NEFH UCSF GRCh37 22 29881757 29881757 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 18 32 0 ENST00000310624.6:c.1129G>A p.Glu377Lys p.E377K ENST00000310624 NM_021076.3 377 Gag/Aag 0 +NET1 UCSF GRCh37 10 5498729 5498729 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 45 84 0 ENST00000355029.4:c.1563G>A p.Glu521= p.E521= ENST00000355029 NM_001047160.2 521 gaG/gaA 0 +NFATC4 UCSF GRCh37 14 24843593 24843593 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 10 34 0 ENST00000413692.2:c.1983G>A p.Val661= p.V661= ENST00000413692 NM_001198967.1 661 gtG/gtA 0 +NFE2L1 UCSF GRCh37 17 46128766 46128766 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 61 49 0 ENST00000362042.3:c.286C>T p.Pro96Ser p.P96S ENST00000362042 NM_003204.2 96 Cca/Tca 0 +NFE2L1 UCSF GRCh37 17 46128657 46128657 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 74 99 0 ENST00000362042.3:c.177G>A p.Arg59= p.R59= ENST00000362042 NM_003204.2 59 agG/agA 0 +NFE2L2 UCSF GRCh37 2 178095714 178095714 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 141 84 116 0 ENST00000397062.3:c.1617G>A p.Leu539= p.L539= ENST00000397062 NM_006164.4 539 ttG/ttA 0 +NFRKB UCSF GRCh37 11 129755423 129755423 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 18 37 0 ENST00000524794.1:c.586G>A p.Glu196Lys p.E196K ENST00000524794 196 Gag/Aag 0 +NID1 UCSF GRCh37 1 236154275 236154275 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 19 35 0 ENST00000264187.6:c.2839C>T p.Leu947Phe p.L947F ENST00000264187 NM_002508.2 947 Ctc/Ttc 0 +NID2 UCSF GRCh37 14 52508869 52508869 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 35 72 0 ENST00000216286.5:c.1779C>T p.Leu593= p.L593= ENST00000216286 NM_007361.3 593 ctC/ctT 0 +NINL UCSF GRCh37 20 25456771 25456771 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 163 75 59 0 ENST00000278886.6:c.3156G>A p.Glu1052= p.E1052= ENST00000278886 NM_025176.4 1052 gaG/gaA 0 +NIPAL3 UCSF GRCh37 1 24776049 24776049 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 30 42 0 ENST00000374399.4:c.473G>A p.Ser158Asn p.S158N ENST00000374399 NM_020448.4 158 aGt/aAt 0 +NLRP1 UCSF GRCh37 17 5425059 5425059 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 23 33 0 ENST00000572272.1:c.3568G>A p.Glu1190Lys p.E1190K ENST00000572272 1190 Gag/Aag 0 +NLRP5 UCSF GRCh37 19 56530765 56530765 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 81 154 0 ENST00000390649.3:c.622+1G>A p.X208_splice ENST00000390649 NM_153447.4 0 +NMT2 UCSF GRCh37 10 15151773 15151773 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 111 53 95 0 ENST00000378165.4:c.1404G>A p.Lys468= p.K468= ENST00000378165 NM_004808.2 468 aaG/aaA 0 +NOB1 UCSF GRCh37 16 69782883 69782883 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 23 30 0 ENST00000268802.5:c.664G>A p.Glu222Lys p.E222K ENST00000268802 NM_014062.2 222 Gag/Aag 0 +NOD1 UCSF GRCh37 7 30475661 30475661 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 27 16 0 ENST00000222823.4:c.2574G>A p.Lys858= p.K858= ENST00000222823 NM_006092.2 858 aaG/aaA 0 +NOL9 UCSF GRCh37 1 6585951 6585951 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 140 73 158 0 ENST00000377705.5:c.2072C>T p.Pro691Leu p.P691L ENST00000377705 NM_024654.4 691 cCa/cTa 0 +NOMO2 UCSF GRCh37 16 18544496 18544496 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 228 46 234 0 ENST00000381474.3:c.1226G>A p.Ser409Asn p.S409N ENST00000381474 NM_001004060.1 409 aGt/aAt 0 +NOS1 UCSF GRCh37 12 117693804 117693804 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 25 57 0 ENST00000338101.4:c.2570C>T p.Pro857Leu p.P857L ENST00000338101 857 cCt/cTt 0 +NOS2 UCSF GRCh37 17 26093596 26093596 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 106 73 124 0 ENST00000313735.6:c.2186C>T p.Ala729Val p.A729V ENST00000313735 NM_000625.4 729 gCc/gTc 0 +NOTCH2 UCSF GRCh37 1 120612013 120612013 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.013 P05_Rec Untested WXS Illumina HiSeq 45 9 9 0 ENST00000256646.2:c.8C>T p.Ala3Val p.A3V ENST00000256646 NM_024408.3 3 gCc/gTc 0 +NOTCH2 UCSF GRCh37 1 120612014 120612014 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.013 P05_Rec Untested WXS Illumina HiSeq 45 9 10 0 ENST00000256646.2:c.7G>T p.Ala3Ser p.A3S ENST00000256646 NM_024408.3 3 Gcc/Tcc 0 +NOTCH2 UCSF GRCh37 1 120512351 120512351 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 51 28 47 0 ENST00000256646.2:c.891G>A p.Glu297= p.E297= ENST00000256646 NM_024408.3 297 gaG/gaA 0 +NOTCH4 UCSF GRCh37 6 32168963 32168963 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 39 39 0 ENST00000375023.3:c.4070C>T p.Pro1357Leu p.P1357L ENST00000375023 NM_004557.3 1357 cCc/cTc 0 +NOXA1 UCSF GRCh37 9 140328695 140328695 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 189 60 31 0 ENST00000341349.2:c.1335G>A p.Glu445= p.E445= ENST00000341349 NM_001256067.1 445 gaG/gaA 0 +NPAT UCSF GRCh37 11 108040739 108040739 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 66 111 0 ENST00000278612.8:c.2817G>A p.Gln939= p.Q939= ENST00000278612 NM_002519.2 939 caG/caA 0 +NPHP3 UCSF GRCh37 3 132418210 132418210 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 28 7 21 0 ENST00000337331.5:c.1972C>T p.Pro658Ser p.P658S ENST00000337331 NM_153240.4 658 Cct/Tct 0 +NPHP4 UCSF GRCh37 1 5940222 5940222 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 54 81 0 ENST00000378156.4:c.2563G>A p.Ala855Thr p.A855T ENST00000378156 NM_015102.3 855 Gcc/Acc 0 +NPHS1 UCSF GRCh37 19 36333406 36333406 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 45 37 0 ENST00000378910.5:c.2381C>T p.Ser794Phe p.S794F ENST00000378910 NM_004646.3 794 tCc/tTc 0 +NQO2 UCSF GRCh37 6 3015855 3015855 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 29 14 32 0 ENST00000338130.2:c.395T>C p.Phe132Ser p.F132S ENST00000338130 132 tTc/tCc 0 +NR1H2 UCSF GRCh37 19 50882000 50882000 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 60 38 0 ENST00000253727.5:c.694G>A p.Ala232Thr p.A232T ENST00000253727 NM_007121.5 232 Gcg/Acg 0 +NR1H4 UCSF GRCh37 12 100957206 100957206 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 45 87 0 ENST00000551379.1:c.1400C>T p.Ser467Leu p.S467L ENST00000551379 467 tCa/tTa 0 +NR2C1 UCSF GRCh37 12 95456424 95456424 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 38 20 38 0 ENST00000333003.5:c.145C>G p.His49Asp p.H49D ENST00000333003 NM_003297.3 49 Cac/Gac 0 +NR2C1 UCSF GRCh37 12 95456371 95456371 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0014 P05_Rec Untested WXS Illumina HiSeq 28 17 30 0 ENST00000333003.5:c.198G>A p.Pro66= p.P66= ENST00000333003 NM_003297.3 66 ccG/ccA 0 +NRG1 UCSF GRCh37 8 32453351 32453351 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 44 81 0 ENST00000356819.4:c.106C>T p.Pro36Ser p.P36S ENST00000356819 NM_013956.3 36 Cct/Tct 0 +NRL UCSF GRCh37 14 24551985 24551985 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 21 23 0 ENST00000561028.1:c.73C>T p.Arg25Trp p.R25W ENST00000561028 25 Cgg/Tgg 0 +NRSN1 UCSF GRCh37 6 24145818 24145818 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 82 54 95 0 ENST00000378491.4:c.232A>C p.Thr78Pro p.T78P ENST00000378491 NM_080723.4 78 Act/Cct 0 +NRXN3 UCSF GRCh37 14 79117661 79117661 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 77 145 0 ENST00000554719.1:c.94C>T p.Leu32Phe p.L32F ENST00000554719 NM_004796.5 32 Ctt/Ttt 0 +NSMAF UCSF GRCh37 8 59496711 59496711 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 37 97 0 ENST00000427130.2:c.2801C>T p.Thr934Ile p.T934I ENST00000427130 NM_001144772.1 934 aCa/aTa 0 +NTRK3 UCSF GRCh37 15 88679226 88679226 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 41 73 0 ENST00000360948.2:c.811G>A p.Val271Met p.V271M ENST00000360948 NM_001012338.2 271 Gtg/Atg 0 +NUDC UCSF GRCh37 1 27272131 27272131 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 85 36 110 0 ENST00000321265.5:c.898G>A p.Gly300Arg p.G300R ENST00000321265 NM_006600.3 300 Ggg/Agg 0 +NUDCD2 UCSF GRCh37 5 162886898 162886898 + synonymous_variant Silent SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 15 29 1 ENST00000302764.4:c.159G>T p.Ala53= p.A53= ENST00000302764 NM_145266.4 53 gcG/gcT 0 +NUDCD3 UCSF GRCh37 7 44467172 44467172 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 19 51 0 ENST00000355451.7:c.640C>T p.Gln214Ter p.Q214* ENST00000355451 NM_015332.3 214 Cag/Tag 0 +NUMB UCSF GRCh37 14 73750891 73750891 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 59 92 0 ENST00000355058.3:c.847C>T p.Leu283Phe p.L283F ENST00000355058 283 Ctt/Ttt 0 +NUP188 UCSF GRCh37 9 131735512 131735512 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 17 29 0 ENST00000372577.2:c.1187C>T p.Thr396Ile p.T396I ENST00000372577 NM_015354.2 396 aCc/aTc 0 +NUP210 UCSF GRCh37 3 13393458 13393458 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 19 56 0 ENST00000254508.5:c.2756G>A p.Gly919Asp p.G919D ENST00000254508 NM_024923.3 919 gGc/gAc 0 +NUP210 UCSF GRCh37 3 13401975 13401975 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 12 22 0 ENST00000254508.5:c.1949C>T p.Ser650Phe p.S650F ENST00000254508 NM_024923.3 650 tCt/tTt 0 +NUP93 UCSF GRCh37 16 56878490 56878490 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 18 40 0 ENST00000308159.5:c.2429G>A p.Arg810Lys p.R810K ENST00000308159 NM_014669.4 810 aGg/aAg 0 +NUPL1 UCSF GRCh37 13 25905498 25905498 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 41 58 0 ENST00000381736.3:c.1237C>T p.Leu413= p.L413= ENST00000381736 NM_014089.3 413 Ctg/Ttg 0 +NXF3 UCSF GRCh37 X 102337686 102337686 + splice_donor_variant Splice_Site SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 58 34 112 0 ENST00000395065.3:c.780+2T>G p.X260_splice ENST00000395065 NM_022052.1 0 +OAS1 UCSF GRCh37 12 113349034 113349034 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0015 P05_Rec Untested WXS Illumina HiSeq 70 29 75 0 ENST00000445409.2:c.648C>T p.Tyr216= p.Y216= ENST00000445409 NM_001032409.1 216 taC/taT 0 +OAS2 UCSF GRCh37 12 113436196 113436196 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 149 43 109 0 ENST00000342315.4:c.989C>T p.Ala330Val p.A330V ENST00000342315 NM_016817.2 330 gCa/gTa 0 +OASL UCSF GRCh37 12 121458523 121458523 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 38 68 0 ENST00000257570.5:c.1386G>A p.Gln462= p.Q462= ENST00000257570 NM_003733.3 462 caG/caA 0 +OBSCN UCSF GRCh37 1 228476566 228476566 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 57 67 0 ENST00000570156.2:c.11603C>T p.Thr3868Ile p.T3868I ENST00000570156 NM_001271223.2 3868 aCc/aTc 0 +OBSCN UCSF GRCh37 1 228403510 228403510 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 24 23 0 ENST00000570156.2:c.2075G>A p.Ser692Asn p.S692N ENST00000570156 NM_001271223.2 692 aGc/aAc 0 +OBSCN UCSF GRCh37 1 228497197 228497197 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 44 75 0 ENST00000570156.2:c.15820G>A p.Asp5274Asn p.D5274N ENST00000570156 NM_001271223.2 5274 Gat/Aat 0 +OBSCN UCSF GRCh37 1 228481893 228481893 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 155 102 130 0 ENST00000570156.2:c.12459G>A p.Glu4153= p.E4153= ENST00000570156 NM_001271223.2 4153 gaG/gaA 0 +ODF2 UCSF GRCh37 9 131262353 131262353 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 40 58 0 ENST00000434106.3:c.2309G>A p.Arg770His p.R770H ENST00000434106 NM_153433.1 770 cGc/cAc 0 +ODZ2 UCSF GRCh37 5 167420045 167420045 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0034 P05_Rec Untested WXS Illumina HiSeq 37 60 98 0 ENST00000518659.1:c.1044G>A p.Pro348= p.P348= ENST00000518659 NM_001122679.1 348 ccG/ccA 0 +ODZ4 UCSF GRCh37 11 78413374 78413374 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 131 117 150 0 ENST00000278550.7:c.4284G>A p.Val1428= p.V1428= ENST00000278550 NM_001098816.2 1428 gtG/gtA 0 +OGFR UCSF GRCh37 20 61444600 61444600 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.039,1000g2011may_all_0.0976,snp132_rs6122313 P05_Rec Untested WXS Illumina HiSeq 25 7 10 0 ENST00000290291.6:c.1633C>A p.Arg545Ser p.R545S ENST00000290291 NM_007346.2 545 Cgc/Agc 0 +OLFM1 UCSF GRCh37 9 137987827 137987827 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 106 35 44 0 ENST00000252854.4:c.364G>A p.Glu122Lys p.E122K ENST00000252854 NM_014279.4 122 Gag/Aag 0 +OLFM4 UCSF GRCh37 13 53624333 53624333 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 66 115 0 ENST00000219022.2:c.960G>A p.Glu320= p.E320= ENST00000219022 NM_006418.4 320 gaG/gaA 0 +OPRM1 UCSF GRCh37 6 154360645 154360645 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 13 14 0 ENST00000434900.2:c.245C>T p.Thr82Ile p.T82I ENST00000434900 NM_001145279.2 82 aCc/aTc 0 +OPTN UCSF GRCh37 10 13169851 13169851 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 45 92 0 ENST00000378748.3:c.1349C>T p.Thr450Ile p.T450I ENST00000378748 NM_001008211.1 450 aCc/aTc 0 +OR10AG1 UCSF GRCh37 11 55735468 55735468 + missense_variant Missense_Mutation SNP G G A snp132_rs77704611 P05_Rec Untested WXS Illumina HiSeq 40 35 61 0 ENST00000312345.2:c.472C>T p.Pro158Ser p.P158S ENST00000312345 NM_001005491.1 158 Ccc/Tcc 0 +OR10G9 UCSF GRCh37 11 123894533 123894533 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 60 114 0 ENST00000375024.1:c.814G>A p.Ala272Thr p.A272T ENST00000375024 NM_001001953.1 272 Gcc/Acc 0 +OR10J3 UCSF GRCh37 1 159283715 159283715 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 63 105 0 ENST00000332217.5:c.735C>T p.His245= p.H245= ENST00000332217 NM_001004467.1 245 caC/caT 0 +OR10T2 UCSF GRCh37 1 158368825 158368825 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 36 114 0 ENST00000334438.1:c.432G>A p.Glu144= p.E144= ENST00000334438 NM_001004475.1 144 gaG/gaA 0 +OR1E2 UCSF GRCh37 17 3336691 3336691 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 43 30 55 0 ENST00000248384.1:c.445C>G p.Leu149Val p.L149V ENST00000248384 NM_003554.1 149 Ctc/Gtc 0 +OR1L8 UCSF GRCh37 9 125329947 125329947 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 25 80 0 ENST00000304865.2:c.810G>A p.Lys270= p.K270= ENST00000304865 NM_001004454.1 270 aaG/aaA 0 +OR2A25 UCSF GRCh37 7 143771842 143771842 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 223 80 170 0 ENST00000408898.2:c.530T>G p.Phe177Cys p.F177C ENST00000408898 NM_001004488.1 177 tTc/tGc 0 +OR2C1 UCSF GRCh37 16 3406567 3406567 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 46 74 0 ENST00000304936.2:c.627C>T p.Val209= p.V209= ENST00000304936 NM_012368.2 209 gtC/gtT 0 +OR56A5 UCSF GRCh37 11 5989353 5989353 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 66 179 0 ENST00000532411.1:n.372C>T *124* ENST00000532411 0 +OR5V1 UCSF GRCh37 6 29323969 29323969 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 29 42 0 ENST00000377154.1:c.4G>A p.Glu2Lys p.E2K ENST00000377154 2 Gaa/Aaa 0 +OR6V1 UCSF GRCh37 7 142749760 142749760 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 156 55 107 0 ENST00000418316.1:c.323C>T p.Thr108Ile p.T108I ENST00000418316 NM_001001667.1 108 aCc/aTc 0 +OR7A5 UCSF GRCh37 19 14938928 14938928 + synonymous_variant Silent SNP G G A snp132_rs76014757 P05_Rec Untested WXS Illumina HiSeq 133 83 141 0 ENST00000322301.3:c.126C>T p.Asn42= p.N42= ENST00000322301 42 aaC/aaT 0 +OR7G1 UCSF GRCh37 19 9226037 9226037 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 64 171 0 ENST00000541538.1:c.403C>T p.Leu135Phe p.L135F ENST00000541538 NM_001005192.2 135 Ctc/Ttc 0 +OR8H1 UCSF GRCh37 11 56057643 56057643 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 77 133 0 ENST00000313022.2:c.896C>T p.Ala299Val p.A299V ENST00000313022 NM_001005199.1 299 gCt/gTt 0 +OSBPL10 UCSF GRCh37 3 31725542 31725542 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 31 37 0 ENST00000396556.2:c.1310C>T p.Ala437Val p.A437V ENST00000396556 NM_017784.4 437 gCg/gTg 0 +OSBPL11 UCSF GRCh37 3 125271277 125271277 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 45 68 0 ENST00000296220.5:c.1402G>A p.Val468Ile p.V468I ENST00000296220 NM_022776.4 468 Gta/Ata 0 +OSBPL5 UCSF GRCh37 11 3111847 3111847 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 17 27 16 0 ENST00000263650.7:c.2339C>T p.Ser780Phe p.S780F ENST00000263650 NM_020896.3 780 tCc/tTc 0 +OTUD4 UCSF GRCh37 4 146077122 146077122 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 19 28 38 0 ENST00000454497.2:c.461A>C p.Asp154Ala p.D154A ENST00000454497 NM_001102653.1 154 gAt/gCt 0 +OTUD7A UCSF GRCh37 15 31862393 31862393 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 36 36 0 ENST00000307050.4:c.159C>T p.Asn53= p.N53= ENST00000307050 NM_130901.1 53 aaC/aaT 0 +OXA1L UCSF GRCh37 14 23235862 23235862 + synonymous_variant Silent SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 128 82 93 0 ENST00000285848.5:c.132T>C p.Gly44= p.G44= ENST00000285848 NM_005015.3 44 ggT/ggC 0 +PADI2 UCSF GRCh37 1 17413169 17413169 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 61 35 45 0 ENST00000375486.4:c.681C>T p.Ile227= p.I227= ENST00000375486 NM_007365.2 227 atC/atT 0 +PADI6 UCSF GRCh37 1 17727751 17727751 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 34 62 0 ENST00000434762.2:n.1953G>A *651* ENST00000434762 0 +PALMD UCSF GRCh37 1 100155175 100155175 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 23 61 0 ENST00000263174.4:c.1359G>A p.Glu453= p.E453= ENST00000263174 NM_017734.4 453 gaG/gaA 0 +PANK1 UCSF GRCh37 10 91348448 91348448 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 24 37 56 0 ENST00000307534.4:c.1698G>A p.Trp566Ter p.W566* ENST00000307534 NM_148977.2 566 tgG/tgA 0 +PANK4 UCSF GRCh37 1 2452632 2452632 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 156 75 73 0 ENST00000378466.3:c.330C>T p.Asp110= p.D110= ENST00000378466 NM_018216.1 110 gaC/gaT 0 +PAPLN UCSF GRCh37 14 73733540 73733540 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 9 9 0 ENST00000340738.5:c.3419+1G>A p.X1140_splice ENST00000340738 NM_173462.3 0 +PAPPA2 UCSF GRCh37 1 176661375 176661375 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 76 121 0 ENST00000367662.3:c.2545C>T p.Pro849Ser p.P849S ENST00000367662 NM_020318.2 849 Cca/Tca 0 +PAPPA2 UCSF GRCh37 1 176708825 176708825 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 43 26 42 0 ENST00000367662.3:c.3862G>C p.Val1288Leu p.V1288L ENST00000367662 NM_020318.2 1288 Gtt/Ctt 0 +PARP1 UCSF GRCh37 1 226579986 226579986 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 154 92 143 0 ENST00000366794.5:c.316G>A p.Ala106Thr p.A106T ENST00000366794 NM_001618.3 106 Gca/Aca 0 +PARVG UCSF GRCh37 22 44585128 44585128 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 33 12 0 ENST00000444313.3:c.382G>A p.Val128Met p.V128M ENST00000444313 NM_022141.6 128 Gtg/Atg 0 +PAXIP1 UCSF GRCh37 7 154755379 154755379 + splice_donor_variant Splice_Site SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 48 15 39 0 ENST00000404141.1:c.1989+2T>C p.X663_splice ENST00000404141 0 +PCDH15 UCSF GRCh37 10 56138586 56138586 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 64 109 0 ENST00000361849.3:c.274C>T p.Gln92Ter p.Q92* ENST00000361849 NM_001142768.1 92 Caa/Taa 0 +PCDH20 UCSF GRCh37 13 61986537 61986537 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 50 89 0 ENST00000409186.1:c.1695G>A p.Glu565= p.E565= ENST00000409186 565 gaG/gaA 0 +PCDHA13 UCSF GRCh37 5 140263138 140263138 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 168 103 0 ENST00000289272.2:c.1285G>A p.Asp429Asn p.D429N ENST00000289272 NM_018904.2 429 Gac/Aac 0 +PCDHA13 UCSF GRCh37 5 140263738 140263738 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 126 51 0 ENST00000289272.2:c.1885G>A p.Gly629Ser p.G629S ENST00000289272 NM_018904.2 629 Ggc/Agc 0 +PCDHB15 UCSF GRCh37 5 140626910 140626910 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 95 44 0 ENST00000231173.3:c.1764G>A p.Lys588= p.K588= ENST00000231173 NM_018935.2 588 aaG/aaA 0 +PCDHB16 UCSF GRCh37 5 140563711 140563711 + missense_variant Missense_Mutation SNP A A C 1000g2011may_all_0.0597,snp132_rs17844652 P05_Rec Untested WXS Illumina HiSeq 41 8 49 1 ENST00000361016.2:c.1577A>C p.Glu526Ala p.E526A ENST00000361016 NM_020957.1 526 gAg/gCg 0 +PCDHB16 UCSF GRCh37 5 140563712 140563712 + missense_variant Missense_Mutation SNP G G T 1000g2011may_all_0.0455,snp132_rs17844653 P05_Rec Untested WXS Illumina HiSeq 41 8 52 1 ENST00000361016.2:c.1578G>T p.Glu526Asp p.E526D ENST00000361016 NM_020957.1 526 gaG/gaT 0 +PCDHGB2 UCSF GRCh37 5 140739819 140739819 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 40 68 0 ENST00000522605.1:c.117G>A p.Glu39= p.E39= ENST00000522605 NM_018923.2 39 gaG/gaA 0 +PCF11 UCSF GRCh37 11 82877001 82877001 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 147 88 97 0 ENST00000298281.4:c.1062G>A p.Lys354= p.K354= ENST00000298281 NM_015885.3 354 aaG/aaA 0 +PCLO UCSF GRCh37 7 82579344 82579344 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 248 87 181 0 ENST00000333891.9:c.10560G>A p.Thr3520= p.T3520= ENST00000333891 NM_033026.5 3520 acG/acA 0 +PCNT UCSF GRCh37 21 47786908 47786908 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 218 132 125 0 ENST00000359568.5:c.3019C>T p.Leu1007Phe p.L1007F ENST00000359568 NM_006031.5 1007 Ctt/Ttt 0 +PCNT UCSF GRCh37 21 47862463 47862463 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 31 15 0 ENST00000359568.5:c.9677C>T p.Ala3226Val p.A3226V ENST00000359568 NM_006031.5 3226 gCa/gTa 0 +PCNT UCSF GRCh37 21 47860958 47860958 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014,snp132_rs78524660 P05_Rec Untested WXS Illumina HiSeq 80 40 49 0 ENST00000359568.5:c.9584G>A p.Arg3195Lys p.R3195K ENST00000359568 NM_006031.5 3195 aGg/aAg 0 +PCNXL2 UCSF GRCh37 1 233134083 233134083 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 30 37 0 ENST00000258229.9:c.5705G>A p.Gly1902Asp p.G1902D ENST00000258229 NM_014801.3 1902 gGt/gAt 0 +PCOLCE UCSF GRCh37 7 100205689 100205689 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 28 57 0 ENST00000223061.5:c.1313C>T p.Pro438Leu p.P438L ENST00000223061 NM_002593.3 438 cCc/cTc 0 +PCOLCE2 UCSF GRCh37 3 142606618 142606618 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 29 38 0 ENST00000295992.3:c.85C>T p.Pro29Ser p.P29S ENST00000295992 NM_013363.3 29 Cct/Tct 0 +PCSK9 UCSF GRCh37 1 55524305 55524305 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 19 23 0 ENST00000302118.5:c.1488G>A p.Arg496= p.R496= ENST00000302118 NM_174936.3 496 cgG/cgA 0 +PDCD11 UCSF GRCh37 10 105178277 105178277 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 44 57 0 ENST00000369797.3:c.1992C>T p.Leu664= p.L664= ENST00000369797 NM_014976.1 664 ctC/ctT 0 +PDE1C UCSF GRCh37 7 31912975 31912975 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 16 37 0 ENST00000396193.1:c.719G>A p.Ser240Asn p.S240N ENST00000396193 NM_001191058.1 240 aGt/aAt 0 +PDE4B UCSF GRCh37 1 66384414 66384414 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 38 69 0 ENST00000329654.4:c.177G>A p.Gln59= p.Q59= ENST00000329654 NM_001037341.1 59 caG/caA 0 +PDE4DIP UCSF GRCh37 1 144852379 144852379 + missense_variant Missense_Mutation SNP G G T 1000g2010nov_all_0.022,1000g2011may_all_0.05769,snp132_rs113954821 P05_Rec Untested WXS Illumina HiSeq 61 10 35 1 ENST00000369356.4:c.7064C>A p.Pro2355His p.P2355H ENST00000369356 NM_014644.5 2355 cCt/cAt 0 +PDGFRA UCSF GRCh37 4 55156572 55156572 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 179 56 89 0 ENST00000257290.5:c.2973C>T p.Val991= p.V991= ENST00000257290 NM_006206.4 991 gtC/gtT 0 +PDK4 UCSF GRCh37 7 95222149 95222149 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 132 49 100 0 ENST00000005178.5:c.452C>T p.Thr151Ile p.T151I ENST00000005178 NM_002612.3 151 aCc/aTc 0 +PDS5A UCSF GRCh37 4 39904041 39904041 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 37 74 0 ENST00000303538.8:c.1425C>T p.Pro475= p.P475= ENST00000303538 NM_001100399.1 475 ccC/ccT 0 +PDZD7 UCSF GRCh37 10 102770636 102770636 + downstream_gene_variant 3'Flank SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 5 11 9 0 ENST00000370220 0 +PEG10 UCSF GRCh37 7 94293624 94293624 + synonymous_variant Silent SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 171 35 39 0 ENST00000482108.1:c.756G>C p.Ser252= p.S252= ENST00000482108 NM_001172437.1 252 tcG/tcC 0 +PER1 UCSF GRCh37 17 8051124 8051124 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 18 17 0 ENST00000317276.4:c.1256C>T p.Pro419Leu p.P419L ENST00000317276 NM_002616.2 419 cCc/cTc 0 +PER3 UCSF GRCh37 1 7869993 7869993 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 32 26 0 ENST00000361923.2:c.1280G>A p.Gly427Glu p.G427E ENST00000361923 NM_016831.1 427 gGg/gAg 0 +PEX1 UCSF GRCh37 7 92131386 92131386 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 231 92 121 0 ENST00000248633.4:c.2234G>A p.Arg745Lys p.R745K ENST00000248633 NM_000466.2 745 aGa/aAa 0 +PFKFB4 UCSF GRCh37 3 48587361 48587361 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 21 49 0 ENST00000232375.3:c.247G>A p.Val83Ile p.V83I ENST00000232375 NM_004567.2 83 Gtc/Atc 0 +PGLYRP2 UCSF GRCh37 19 15587253 15587253 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 35 50 0 ENST00000340880.4:c.228C>T p.Leu76= p.L76= ENST00000340880 NM_052890.3 76 ctC/ctT 0 +PGS1 UCSF GRCh37 17 76399899 76399899 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 60 76 0 ENST00000262764.6:c.1131G>A p.Glu377= p.E377= ENST00000262764 NM_024419.3 377 gaG/gaA 0 +PHACTR1 UCSF GRCh37 6 13206076 13206076 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 134 57 87 0 ENST00000332995.7:c.694C>T p.Leu232= p.L232= ENST00000332995 232 Ctg/Ttg 0 +PHC3 UCSF GRCh37 3 169896720 169896720 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 192 64 182 0 ENST00000495893.2:c.21G>A p.Lys7= p.K7= ENST00000495893 NM_024947.3 7 aaG/aaA 0 +PHF2 UCSF GRCh37 9 96418217 96418217 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 9 11 0 ENST00000359246.4:c.954C>T p.Gly318= p.G318= ENST00000359246 NM_005392.3 318 ggC/ggT 0 +PHF20 UCSF GRCh37 20 34487567 34487567 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 7 40 0 ENST00000374012.3:c.1558C>T p.Pro520Ser p.P520S ENST00000374012 520 Cca/Tca 0 +PHLDB1 UCSF GRCh37 11 118514893 118514893 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 16 8 0 ENST00000361417.2:c.3121+1G>A p.X1041_splice ENST00000361417 NM_015157.3 0 +PHLPP2 UCSF GRCh37 16 71683592 71683592 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 181 69 52 0 ENST00000568954.1:c.3173C>T p.Thr1058Ile p.T1058I ENST00000568954 1058 aCc/aTc 0 +PI15 UCSF GRCh37 8 75757721 75757721 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 53 102 0 ENST00000260113.2:c.630C>T p.Asn210= p.N210= ENST00000260113 NM_015886.3 210 aaC/aaT 0 +PI4KA UCSF GRCh37 22 21159316 21159316 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 62 87 0 ENST00000255882.6:c.1306C>T p.Gln436Ter p.Q436* ENST00000255882 NM_058004.3 436 Cag/Tag 0 +PI4KA UCSF GRCh37 22 21101870 21101870 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 28 52 0 ENST00000255882.6:c.3363+1G>A p.X1121_splice ENST00000255882 NM_058004.3 0 +PI4KA UCSF GRCh37 22 21081530 21081530 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 21 24 0 ENST00000255882.6:c.4929G>A p.Arg1643= p.R1643= ENST00000255882 NM_058004.3 1643 cgG/cgA 0 +PIEZO2 UCSF GRCh37 18 10784940 10784940 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 39 83 0 ENST00000503781.3:c.2334C>T p.Gly778= p.G778= ENST00000503781 NM_022068.2 778 ggC/ggT 0 +PIGQ UCSF GRCh37 16 633059 633059 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 115 79 39 0 ENST00000026218.5:c.1708C>T p.Pro570Ser p.P570S ENST00000026218 NM_148920.2 570 Cca/Tca 0 +PIGR UCSF GRCh37 1 207107863 207107863 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 29 42 0 ENST00000356495.4:c.1607G>A p.Arg536Lys p.R536K ENST00000356495 NM_002644.3 536 aGg/aAg 0 +PIK3CB UCSF GRCh37 3 138433487 138433487 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 80 99 0 ENST00000289153.2:c.1125G>A p.Gly375= p.G375= ENST00000289153 NM_006219.2 375 ggG/ggA 0 +PIK3IP1 UCSF GRCh37 22 31688292 31688292 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 26 67 0 ENST00000215912.5:c.39C>T p.Asn13= p.N13= ENST00000215912 NM_052880.4 13 aaC/aaT 0 +PIK3R1 UCSF GRCh37 5 67591123 67591123 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 55 110 0 ENST00000274335.5:c.1716G>A p.Gln572= p.Q572= ENST00000274335 572 caG/caA 0 +PIN4 UCSF GRCh37 X 71401585 71401585 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 10 19 0 ENST00000373669.2:c.25G>A p.Gly9Arg p.G9R ENST00000373669 NM_006223.3 9 Ggg/Agg 0 +PION UCSF GRCh37 7 76984937 76984937 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 29 71 0 ENST00000257626.7:c.1055G>A p.Gly352Asp p.G352D ENST00000257626 NM_017439.3 352 gGt/gAt 0 +PIP5KL1 UCSF GRCh37 9 130692077 130692077 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 6 9 0 ENST00000388747.4:c.118C>T p.Arg40Cys p.R40C ENST00000388747 NM_001135219.1 40 Cgc/Tgc 0 +PITPNA UCSF GRCh37 17 1438748 1438748 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 56 115 0 ENST00000313486.7:c.521G>A p.Gly174Asp p.G174D ENST00000313486 NM_006224.3 174 gGc/gAc 0 +PIWIL1 UCSF GRCh37 12 130839435 130839435 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 104 30 114 0 ENST00000245255.3:c.1174C>T p.Leu392= p.L392= ENST00000245255 NM_004764.4 392 Cta/Tta 0 +PIWIL3 UCSF GRCh37 22 25115836 25115836 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 11 48 0 ENST00000332271.5:c.2411C>T p.Ser804Phe p.S804F ENST00000332271 NM_001255975.1 804 tCt/tTt 0 +PKD1 UCSF GRCh37 16 2155909 2155909 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 14 12 0 ENST00000262304.4:c.7820A>T p.His2607Leu p.H2607L ENST00000262304 NM_001009944.2 2607 cAc/cTc 0 +PKD1 UCSF GRCh37 16 2160968 2160968 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 54 26 0 ENST00000262304.4:c.4200G>A p.Leu1400= p.L1400= ENST00000262304 NM_001009944.2 1400 ctG/ctA 0 +PKD1L1 UCSF GRCh37 7 47920325 47920325 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 17 61 0 ENST00000289672.2:c.3520+1G>A p.X1174_splice ENST00000289672 NM_138295.3 0 +PKD1L1 UCSF GRCh37 7 47874767 47874767 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 39 14 16 0 ENST00000289672.2:c.6018G>A p.Gly2006= p.G2006= ENST00000289672 NM_138295.3 2006 ggG/ggA 0 +PKD1L1 UCSF GRCh37 7 47968988 47968988 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 141 54 100 0 ENST00000289672.2:c.873C>T p.Asn291= p.N291= ENST00000289672 NM_138295.3 291 aaC/aaT 0 +PKD1L3 UCSF GRCh37 16 71976564 71976564 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 154 46 112 0 ENST00000534738.1:n.4219G>A *1407* ENST00000534738 0 +PKDREJ UCSF GRCh37 22 46657443 46657443 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 35 69 0 ENST00000253255.5:c.1777C>T p.Pro593Ser p.P593S ENST00000253255 NM_006071.1 593 Cct/Tct 0 +PKP1 UCSF GRCh37 1 201293710 201293710 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 12 27 0 ENST00000263946.3:c.1897+1G>A p.X633_splice ENST00000263946 NM_000299.3 0 +PLA1A UCSF GRCh37 3 119316765 119316765 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 4 13 0 ENST00000273371.4:c.5C>T p.Pro2Leu p.P2L ENST00000273371 NM_015900.3 2 cCc/cTc 0 +PLA2R1 UCSF GRCh37 2 160801461 160801461 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 45 77 0 ENST00000283243.7:c.4100C>T p.Ser1367Phe p.S1367F ENST00000283243 NM_001195641.1 1367 tCc/tTc 0 +PLA2R1 UCSF GRCh37 2 160806163 160806163 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 42 71 0 ENST00000283243.7:c.3665C>T p.Ala1222Val p.A1222V ENST00000283243 NM_001195641.1 1222 gCc/gTc 0 +PLCE1 UCSF GRCh37 10 96033478 96033478 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 16 26 69 0 ENST00000371380.3:c.4665+1G>A p.X1555_splice ENST00000371380 0 +PLCG1 UCSF GRCh37 20 39792412 39792412 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 70 102 0 ENST00000373272.2:c.949G>A p.Val317Ile p.V317I ENST00000373272 NM_002660.2 317 Gta/Ata 0 +PLCG1 UCSF GRCh37 20 39798167 39798167 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 46 62 0 ENST00000373272.2:c.2650+1G>A p.X884_splice ENST00000373272 NM_002660.2 0 +PLCH1 UCSF GRCh37 3 155271904 155271904 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 50 15 62 0 ENST00000340059.7:c.1115T>G p.Val372Gly p.V372G ENST00000340059 NM_001130960.1 372 gTt/gGt 0 +PLCL1 UCSF GRCh37 2 198950221 198950221 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 55 45 59 0 ENST00000428675.1:c.1980G>A p.Trp660Ter p.W660* ENST00000428675 NM_006226.3 660 tgG/tgA 0 +PLCL2 UCSF GRCh37 3 17051631 17051631 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 75 77 0 ENST00000418129.2:c.415G>A p.Asp139Asn p.D139N ENST00000418129 NM_001144382.1 139 Gat/Aat 0 +PLCL2 UCSF GRCh37 3 17053574 17053574 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 153 32 73 0 ENST00000418129.2:c.2358G>A p.Trp786Ter p.W786* ENST00000418129 NM_001144382.1 786 tgG/tgA 0 +PLD2 UCSF GRCh37 17 4712455 4712455 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 43 57 0 ENST00000263088.6:c.444C>T p.Pro148= p.P148= ENST00000263088 NM_001243108.1 148 ccC/ccT 0 +PLEKHG1 UCSF GRCh37 6 151152103 151152103 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 43 92 0 ENST00000367328.1:c.1856C>T p.Pro619Leu p.P619L ENST00000367328 NM_001029884.1 619 cCt/cTt 0 +PLEKHH3 UCSF GRCh37 17 40822682 40822682 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 39 28 0 ENST00000591022.1:c.1463C>T p.Ser488Phe p.S488F ENST00000591022 NM_024927.4 488 tCc/tTc 0 +PLEKHM1 UCSF GRCh37 17 43530914 43530914 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 36 77 0 ENST00000430334.3:c.2304G>A p.Trp768Ter p.W768* ENST00000430334 NM_014798.2 768 tgG/tgA 0 +PLEKHM3 UCSF GRCh37 2 208842115 208842115 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 48 102 0 ENST00000427836.2:c.806G>A p.Gly269Asp p.G269D ENST00000427836 NM_001080475.2 269 gGc/gAc 0 +PLEKHM3 UCSF GRCh37 2 208693094 208693094 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 55 96 0 ENST00000427836.2:c.2235G>A p.Glu745= p.E745= ENST00000427836 NM_001080475.2 745 gaG/gaA 0 +PLEKHN1 UCSF GRCh37 1 909744 909744 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 34 30 0 ENST00000379410.3:c.1702G>A p.Asp568Asn p.D568N ENST00000379410 NM_032129.2 568 Gat/Aat 0 +PLEKHO2 UCSF GRCh37 15 65140927 65140927 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 50 75 0 ENST00000323544.4:c.148G>A p.Val50Ile p.V50I ENST00000323544 NM_025201.4 50 Gtc/Atc 0 +PLG UCSF GRCh37 6 161128732 161128732 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 150 66 177 0 ENST00000308192.9:c.186G>A p.Arg62= p.R62= ENST00000308192 NM_000301.3 62 agG/agA 0 +PLIN4 UCSF GRCh37 19 4511827 4511827 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 682 132 341 0 ENST00000301286.3:c.2103C>T p.Val701= p.V701= ENST00000301286 NM_001080400.1 701 gtC/gtT 0 +PLK1S1 UCSF GRCh37 20 21209665 21209665 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 53 89 0 ENST00000457464.1:n.1292G>A *431* ENST00000457464 0 +PLOD2 UCSF GRCh37 3 145788564 145788564 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 41 12 35 0 ENST00000282903.5:c.2217T>G p.His739Gln p.H739Q ENST00000282903 NM_182943.2 739 caT/caG 0 +PLP1 UCSF GRCh37 X 103042780 103042780 + stop_gained Nonsense_Mutation SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 65 78 0 ENST00000418604.1:c.507C>A p.Cys169Ter p.C169* ENST00000418604 NM_001128834.1 169 tgC/tgA 0 +PLS3 UCSF GRCh37 X 114882259 114882259 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 61 98 1 ENST00000420625.2:c.1682C>T p.Ala561Val p.A561V ENST00000420625 NM_001136025.3 561 gCc/gTc 0 +PLSCR4 UCSF GRCh37 3 145924354 145924354 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 31 80 0 ENST00000354952.2:c.313C>T p.Pro105Ser p.P105S ENST00000354952 NM_020353.2 105 Cct/Tct 0 +PLXNB2 UCSF GRCh37 22 50724666 50724666 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0034 P05_Rec Untested WXS Illumina HiSeq 33 68 50 0 ENST00000449103.1:c.1813C>T p.Leu605Phe p.L605F ENST00000449103 605 Ctc/Ttc 0 +PMAIP1 UCSF GRCh37 18 57569967 57569967 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 72 53 85 0 ENST00000316660.6:c.147C>T p.Leu49= p.L49= ENST00000316660 NM_021127.2 49 ctC/ctT 0 +PMEL UCSF GRCh37 12 56348011 56348011 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 41 37 62 0 ENST00000449260.2:c.1994G>A p.Gly665Glu p.G665E ENST00000449260 NM_001200054.1 665 gGg/gAg 0 +PNO1 UCSF GRCh37 2 68385661 68385661 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 41 62 0 ENST00000263657.2:c.357G>A p.Arg119= p.R119= ENST00000263657 NM_020143.2 119 agG/agA 0 +PNPLA6 UCSF GRCh37 19 7623800 7623800 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 30 14 0 ENST00000414982.3:c.3492G>A p.Glu1164= p.E1164= ENST00000414982 NM_001166111.1 1164 gaG/gaA 0 +PNPLA7 UCSF GRCh37 9 140416145 140416145 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 79 32 43 0 ENST00000406427.1:c.900G>A p.Arg300= p.R300= ENST00000406427 NM_001098537.1 300 agG/agA 0 +PNPLA8 UCSF GRCh37 7 108155515 108155515 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 183 53 35 0 ENST00000422087.1:c.421G>A p.Asp141Asn p.D141N ENST00000422087 NM_015723.3 141 Gat/Aat 0 +PNPT1 UCSF GRCh37 2 55912183 55912183 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 25 41 0 ENST00000447944.2:c.298G>A p.Val100Ile p.V100I ENST00000447944 NM_033109.4 100 Gtt/Att 0 +PODN UCSF GRCh37 1 53542970 53542970 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 91 67 0 ENST00000312553.5:c.834C>T p.Arg278= p.R278= ENST00000312553 NM_001199081.1 278 cgC/cgT 0 +POF1B UCSF GRCh37 X 84600880 84600880 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 107 58 119 0 ENST00000262753.4:c.709C>T p.Gln237Ter p.Q237* ENST00000262753 NM_024921.3 237 Cag/Tag 0 +POFUT2 UCSF GRCh37 21 46705667 46705667 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 36 85 0 ENST00000349485.5:c.308C>T p.Pro103Leu p.P103L ENST00000349485 NM_133635.4 103 cCc/cTc 0 +POGZ UCSF GRCh37 1 151384149 151384149 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 19 74 0 ENST00000271715.2:c.1878G>A p.Lys626= p.K626= ENST00000271715 NM_015100.3 626 aaG/aaA 0 +POLD2 UCSF GRCh37 7 44157619 44157619 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 24 48 0 ENST00000406581.2:c.265G>A p.Glu89Lys p.E89K ENST00000406581 NM_001256879.1 89 Gag/Aag 0 +POLD2 UCSF GRCh37 7 44154928 44154928 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 126 33 56 0 ENST00000406581.2:c.1215C>T p.Gly405= p.G405= ENST00000406581 NM_001256879.1 405 ggC/ggT 0 +POLH UCSF GRCh37 6 43581825 43581825 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 52 98 0 ENST00000372236.4:c.1673C>T p.Ser558Phe p.S558F ENST00000372236 NM_006502.2 558 tCc/tTc 0 +POLK UCSF GRCh37 5 74892054 74892054 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 49 58 0 ENST00000241436.4:c.1536G>A p.Arg512= p.R512= ENST00000241436 NM_016218.2 512 cgG/cgA 0 +POLQ UCSF GRCh37 3 121208155 121208155 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 170 54 173 0 ENST00000264233.5:c.3623C>T p.Thr1208Ile p.T1208I ENST00000264233 NM_199420.3 1208 aCc/aTc 0 +POLR1B UCSF GRCh37 2 113308465 113308465 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 68 91 0 ENST00000263331.5:c.648G>A p.Arg216= p.R216= ENST00000263331 NM_019014.4 216 agG/agA 0 +POLR3G UCSF GRCh37 5 89781475 89781475 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 56 101 0 ENST00000399107.1:c.91G>A p.Val31Met p.V31M ENST00000399107 NM_006467.2 31 Gtg/Atg 0 +POM121 UCSF GRCh37 7 72413497 72413497 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 378 72 89 0 ENST00000395270.1:c.2170C>T p.Pro724Ser p.P724S ENST00000395270 NM_001257190.2 724 Ccc/Tcc 0 +POM121 UCSF GRCh37 7 72413724 72413725 + inframe_insertion In_Frame_Ins INS - - CTC NOVEL P05_Rec Untested WXS Illumina HiSeq 6 0 ENST00000395270.1:c.2397_2398insCTC p.Phe799_Phe800insLeu p.F799_F800insL ENST00000395270 NM_001257190.2 799 -/CTC 0 +POMT1 UCSF GRCh37 9 134395559 134395559 + stop_gained Nonsense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 81 30 37 0 ENST00000372228.3:c.1743C>G p.Tyr581Ter p.Y581* ENST00000372228 NM_007171.3 581 taC/taG 0 +POTED UCSF GRCh37 21 14982904 14982904 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.1135 P05_Rec Untested WXS Illumina HiSeq 261 34 178 1 ENST00000299443.5:c.355G>A p.Ala119Thr p.A119T ENST00000299443 NM_174981.3 119 Gct/Act 0 +POTEF UCSF GRCh37 2 130877870 130877870 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 270 161 206 0 ENST00000357462.5:c.219G>A p.Arg73= p.R73= ENST00000357462 73 agG/agA 0 +POU4F1 UCSF GRCh37 13 79175722 79175722 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 66 40 0 ENST00000377208.5:c.1088C>T p.Ala363Val p.A363V ENST00000377208 NM_006237.3 363 gCc/gTc 0 +PPFIA2 UCSF GRCh37 12 81661691 81661691 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 68 55 0 ENST00000549396.1:c.3486G>A p.Gln1162= p.Q1162= ENST00000549396 NM_003625.3 1162 caG/caA 0 +PPFIBP1 UCSF GRCh37 12 27844847 27844847 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 40 97 0 ENST00000318304.8:c.2869G>A p.Asp957Asn p.D957N ENST00000318304 NM_177444.2 957 Gac/Aac 0 +PPIB UCSF GRCh37 15 64448978 64448978 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 112 82 89 0 ENST00000300026.3:c.474G>A p.Lys158= p.K158= ENST00000300026 NM_000942.4 158 aaG/aaA 0 +PPME1 UCSF GRCh37 11 73962009 73962009 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 36 88 0 ENST00000328257.8:c.1020G>A p.Gln340= p.Q340= ENST00000328257 NM_016147.2 340 caG/caA 0 +PPP1R12A UCSF GRCh37 12 80202309 80202309 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 61 91 0 ENST00000450142.2:c.1504C>T p.Pro502Ser p.P502S ENST00000450142 NM_002480.2 502 Cca/Tca 0 +PPP1R15B UCSF GRCh37 1 204378931 204378931 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 52 44 63 0 ENST00000367188.4:c.1609T>C p.Ser537Pro p.S537P ENST00000367188 NM_032833.3 537 Tct/Cct 0 +PPP1R9A UCSF GRCh37 7 94539568 94539568 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 34 48 0 ENST00000433360.1:c.143G>A p.Gly48Asp p.G48D ENST00000433360 NM_001166160.1 48 gGt/gAt 0 +PPP1R9B UCSF GRCh37 17 48212917 48212917 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 46 56 0 ENST00000316878.6:c.2394+1G>A p.X798_splice ENST00000316878 NM_032595.3 0 +PPP6R1 UCSF GRCh37 19 55743017 55743017 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 16 10 0 ENST00000412770.2:c.2326C>T p.Pro776Ser p.P776S ENST00000412770 NM_014931.3 776 Ccc/Tcc 0 +PPP6R1 UCSF GRCh37 19 55743302 55743302 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 20 12 0 ENST00000412770.2:c.2174C>T p.Thr725Ile p.T725I ENST00000412770 NM_014931.3 725 aCc/aTc 0 +PPP6R2 UCSF GRCh37 22 50877097 50877097 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 21 38 33 0 ENST00000395741.3:c.1956G>A p.Lys652= p.K652= ENST00000395741 652 aaG/aaA 0 +PRAMEF1 UCSF GRCh37 1 12854622 12854622 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 153 66 149 0 ENST00000332296.7:c.846G>A p.Gly282= p.G282= ENST00000332296 NM_023013.2 282 ggG/ggA 0 +PRAMEF12 UCSF GRCh37 1 12837214 12837214 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 152 77 135 0 ENST00000357726.4:c.924C>T p.Asp308= p.D308= ENST00000357726 NM_001080830.1 308 gaC/gaT 0 +PRDM10 UCSF GRCh37 11 129800986 129800986 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 56 43 0 ENST00000358825.5:c.1455G>A p.Pro485= p.P485= ENST00000358825 NM_020228.2 485 ccG/ccA 0 +PRDM15 UCSF GRCh37 21 43274688 43274688 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 30 20 0 ENST00000269844.3:c.1623C>T p.Gly541= p.G541= ENST00000269844 NM_022115.3 541 ggC/ggT 0 +PRDM4 UCSF GRCh37 12 108128109 108128109 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 181 83 142 0 ENST00000228437.5:c.2284C>T p.Pro762Ser p.P762S ENST00000228437 NM_012406.3 762 Cca/Tca 0 +PRDM4 UCSF GRCh37 12 108134731 108134731 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 107 47 76 0 ENST00000228437.5:c.1916T>C p.Ile639Thr p.I639T ENST00000228437 NM_012406.3 639 aTa/aCa 0 +PRDM8 UCSF GRCh37 4 81123189 81123189 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 57 48 0 ENST00000339711.4:c.573C>T p.Asp191= p.D191= ENST00000339711 NM_020226.3 191 gaC/gaT 0 +PREP UCSF GRCh37 6 105825268 105825268 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 64 103 0 ENST00000369110.3:c.247G>A p.Gly83Arg p.G83R ENST00000369110 NM_002726.4 83 Gga/Aga 0 +PREX1 UCSF GRCh37 20 47270005 47270005 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 110 55 93 0 ENST00000371941.3:c.2240C>T p.Ala747Val p.A747V ENST00000371941 NM_020820.3 747 gCt/gTt 0 +PREX1 UCSF GRCh37 20 47309310 47309310 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 41 65 0 ENST00000371941.3:c.936G>A p.Lys312= p.K312= ENST00000371941 NM_020820.3 312 aaG/aaA 0 +PREX1 UCSF GRCh37 20 47269244 47269244 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 32 38 0 ENST00000371941.3:c.2347G>A p.Gly783Ser p.G783S ENST00000371941 NM_020820.3 783 Ggc/Agc 0 +PRG4 UCSF GRCh37 1 186276268 186276291 + inframe_deletion In_Frame_Del DEL GAGCCTGCACCCACCACTCCCAAA GAGCCTGCACCCACCACTCCCAAA - NOVEL P05_Rec Untested WXS Illumina HiSeq 33 0 ENST00000445192.2:c.1431_1454del p.Thr478_Thr485del p.T478_T485del ENST00000445192 NM_005807.3 473 GAGCCTGCACCCACCACTCCCAAA/- 0 +PRIMA1 UCSF GRCh37 14 94203672 94203672 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 13 47 0 ENST00000393140.1:c.274G>A p.Gly92Arg p.G92R ENST00000393140 NM_178013.3 92 Ggg/Agg 0 +PRKAB2 UCSF GRCh37 1 146639345 146639345 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 134 85 132 0 ENST00000254101.3:c.323+1G>A p.X108_splice ENST00000254101 NM_005399.4 0 +PRKAG2 UCSF GRCh37 7 151273519 151273519 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 10 16 0 ENST00000287878.4:c.884C>T p.Ala295Val p.A295V ENST00000287878 NM_016203.3 295 gCt/gTt 0 +PRKAR1B UCSF GRCh37 7 720262 720262 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 29 29 0 ENST00000406797.1:c.279C>T p.Ala93= p.A93= ENST00000406797 NM_001164761.1 93 gcC/gcT 0 +PRKAR2B UCSF GRCh37 7 106799893 106799893 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 19 75 0 ENST00000265717.4:c.1124-1G>A p.X375_splice ENST00000265717 NM_002736.2 0 +PRKCE UCSF GRCh37 2 46378252 46378252 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 5 19 15 0 ENST00000306156.3:c.1804G>A p.Ala602Thr p.A602T ENST00000306156 NM_005400.2 602 Gct/Act 0 +PRKCH UCSF GRCh37 14 61915909 61915909 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 31 43 0 ENST00000332981.5:c.641G>A p.Cys214Tyr p.C214Y ENST00000332981 NM_006255.3 214 tGc/tAc 0 +PRKCZ UCSF GRCh37 1 2087490 2087490 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 117 64 120 0 ENST00000378567.3:c.933C>T p.Pro311= p.P311= ENST00000378567 NM_002744.4 311 ccC/ccT 0 +PRKDC UCSF GRCh37 8 48715922 48715922 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 107 60 80 0 ENST00000314191.2:c.9864G>A p.Arg3288= p.R3288= ENST00000314191 NM_006904.6 3288 cgG/cgA 0 +PRKG2 UCSF GRCh37 4 82031649 82031649 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 29 66 0 ENST00000395578.1:c.1893G>A p.Val631= p.V631= ENST00000395578 631 gtG/gtA 0 +PRLHR UCSF GRCh37 10 120354123 120354123 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 9 23 10 0 ENST00000239032.2:c.634G>A p.Glu212Lys p.E212K ENST00000239032 NM_004248.2 212 Gag/Aag 0 +PRM3 UCSF GRCh37 16 11367397 11367397 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 6 8 0 ENST00000327157.2:c.56G>A p.Gly19Asp p.G19D ENST00000327157 NM_021247.1 19 gGc/gAc 0 +PROK1 UCSF GRCh37 1 110996646 110996646 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 23 11 0 ENST00000271331.3:c.136G>A p.Gly46Arg p.G46R ENST00000271331 NM_032414.2 46 Ggg/Agg 0 +PROX2 UCSF GRCh37 14 75330486 75330486 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 25 51 0 ENST00000556084.2:c.52C>T p.Leu18= p.L18= ENST00000556084 NM_001080408.2 18 Cta/Tta 0 +PRR14 UCSF GRCh37 16 30664057 30664057 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 42 44 0 ENST00000542965.2:c.208T>A p.Ser70Thr p.S70T ENST00000542965 70 Tca/Aca 0 +PRRC2A UCSF GRCh37 6 31592294 31592294 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 22 15 0 ENST00000376033.2:c.458G>A p.Gly153Glu p.G153E ENST00000376033 NM_004638.3 153 gGa/gAa 0 +PRRC2B UCSF GRCh37 9 134350643 134350643 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 41 33 0 ENST00000357304.4:c.3127C>T p.Pro1043Ser p.P1043S ENST00000357304 NM_013318.3 1043 Ccc/Tcc 0 +PRRC2C UCSF GRCh37 1 171509690 171509690 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 62 61 0 ENST00000338920.4:c.3079G>A p.Glu1027Lys p.E1027K ENST00000338920 NM_015172.3 1027 Gaa/Aaa 0 +PRRC2C UCSF GRCh37 1 171514630 171514630 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 42 52 0 ENST00000338920.4:c.4770C>T p.Asp1590= p.D1590= ENST00000338920 NM_015172.3 1590 gaC/gaT 0 +PRSS48 UCSF GRCh37 4 152212490 152212490 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 80 90 0 ENST00000455694.2:c.872C>T p.Pro291Leu p.P291L ENST00000455694 NM_183375.2 291 cCc/cTc 0 +PRSS57 UCSF GRCh37 19 686978 686978 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 19 17 0 ENST00000329267.7:c.592C>T p.Leu198Phe p.L198F ENST00000329267 NM_214710.3 198 Ctt/Ttt 0 +PRUNE UCSF GRCh37 1 150999738 150999738 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 11 32 0 ENST00000271620.3:c.709G>T p.Asp237Tyr p.D237Y ENST00000271620 NM_021222.1 237 Gac/Tac 0 +PSG4 UCSF GRCh37 19 43699353 43699353 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 173 106 226 0 ENST00000405312.3:c.782C>T p.Thr261Ile p.T261I ENST00000405312 NM_002780.4 261 aCc/aTc 0 +PSG8 UCSF GRCh37 19 43259405 43259405 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 86 237 0 ENST00000306511.4:c.723G>A p.Lys241= p.K241= ENST00000306511 NM_182707.2 241 aaG/aaA 0 +PSMD1 UCSF GRCh37 2 232028412 232028412 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 17 35 66 0 ENST00000308696.6:c.2452G>A p.Glu818Lys p.E818K ENST00000308696 NM_002807.3 818 Gaa/Aaa 0 +PSMD2 UCSF GRCh37 3 184017640 184017640 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 114 28 67 0 ENST00000310118.4:c.137C>T p.Ser46Phe p.S46F ENST00000310118 NM_002808.4 46 tCt/tTt 0 +PSME4 UCSF GRCh37 2 54117319 54117319 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 54 102 0 ENST00000404125.1:c.4218C>T p.Cys1406= p.C1406= ENST00000404125 NM_014614.2 1406 tgC/tgT 0 +PSTPIP2 UCSF GRCh37 18 43578776 43578776 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 51 61 0 ENST00000409746.5:c.546C>T p.Thr182= p.T182= ENST00000409746 NM_024430.3 182 acC/acT 0 +PTCH1 UCSF GRCh37 9 98231306 98231306 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 107 48 66 0 ENST00000331920.6:c.1977G>A p.Gln659= p.Q659= ENST00000331920 NM_000264.3 659 caG/caA 0 +PTCHD2 UCSF GRCh37 1 11580875 11580875 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 20 11 0 ENST00000294484.6:c.2332G>A p.Ala778Thr p.A778T ENST00000294484 NM_020780.1 778 Gcc/Acc 0 +PTH1R UCSF GRCh37 3 46939927 46939927 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 17 20 30 0 ENST00000313049.5:c.603C>T p.Ser201= p.S201= ENST00000313049 201 tcC/tcT 0 +PTH2R UCSF GRCh37 2 209358284 209358284 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 106 69 67 0 ENST00000272847.2:c.1553G>A p.Gly518Glu p.G518E ENST00000272847 NM_005048.3 518 gGg/gAg 0 +PTPN13 UCSF GRCh37 4 87691066 87691066 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 147 75 139 0 ENST00000436978.1:c.4649G>A p.Ser1550Asn p.S1550N ENST00000436978 NM_080685.2 1550 aGt/aAt 0 +PTPN13 UCSF GRCh37 4 87556525 87556525 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 34 62 0 ENST00000436978.1:c.115+1G>A p.X39_splice ENST00000436978 NM_080685.2 0 +PTPN9 UCSF GRCh37 15 75819501 75819501 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 24 34 0 ENST00000306726.2:c.165G>A p.Lys55= p.K55= ENST00000306726 NM_002833.2 55 aaG/aaA 0 +PTPRB UCSF GRCh37 12 70928355 70928355 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 13 11 0 ENST00000334414.6:c.6281C>T p.Thr2094Ile p.T2094I ENST00000334414 NM_001109754.2 2094 aCc/aTc 0 +PTPRD UCSF GRCh37 9 8331732 8331732 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 31 61 0 ENST00000356435.5:c.5384G>A p.Gly1795Asp p.G1795D ENST00000356435 1795 gGc/gAc 0 +PTPRD UCSF GRCh37 9 8518062 8518062 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 140 63 154 0 ENST00000356435.5:c.1329G>A p.Glu443= p.E443= ENST00000356435 443 gaG/gaA 0 +PTPRS UCSF GRCh37 19 5244361 5244361 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 49 50 0 ENST00000357368.4:c.1121G>A p.Gly374Glu p.G374E ENST00000357368 NM_002850.3 374 gGg/gAg 0 +PTPRS UCSF GRCh37 19 5231583 5231583 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 12 11 0 ENST00000357368.4:c.1893C>T p.Arg631= p.R631= ENST00000357368 NM_002850.3 631 cgC/cgT 0 +PTPRZ1 UCSF GRCh37 7 121653840 121653840 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 192 50 146 0 ENST00000393386.2:c.4740G>A p.Gly1580= p.G1580= ENST00000393386 NM_001206838.1 1580 ggG/ggA 0 +PWP2 UCSF GRCh37 21 45545915 45545915 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 30 55 0 ENST00000291576.7:c.1989G>A p.Met663Ile p.M663I ENST00000291576 NM_005049.2 663 atG/atA 0 +PWWP2A UCSF GRCh37 5 159545853 159545853 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 11 18 12 0 ENST00000307063.7:c.543G>A p.Gly181= p.G181= ENST00000307063 NM_001130864.1 181 ggG/ggA 0 +PWWP2B UCSF GRCh37 10 134218986 134218986 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 20 13 0 ENST00000305233.5:c.982C>T p.Leu328= p.L328= ENST00000305233 NM_138499.3 328 Ctg/Ttg 0 +PXK UCSF GRCh37 3 58398660 58398660 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 30 87 0 ENST00000356151.2:c.1498C>T p.Pro500Ser p.P500S ENST00000356151 NM_017771.3 500 Ccg/Tcg 0 +QRICH2 UCSF GRCh37 17 74288835 74288835 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 31 54 0 ENST00000262765.5:c.1475G>A p.Gly492Asp p.G492D ENST00000262765 NM_032134.1 492 gGt/gAt 0 +R3HDM1 UCSF GRCh37 2 136403047 136403047 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 37 53 0 ENST00000264160.4:c.1573C>T p.Pro525Ser p.P525S ENST00000264160 NM_015361.2 525 Cct/Tct 0 +R3HDM2 UCSF GRCh37 12 57662174 57662174 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 36 57 0 ENST00000347140.3:c.1900G>A p.Val634Met p.V634M ENST00000347140 634 Gtg/Atg 0 +RAB32 UCSF GRCh37 6 146870851 146870851 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 21 52 0 ENST00000367495.3:c.502G>A p.Ala168Thr p.A168T ENST00000367495 NM_006834.3 168 Gcc/Acc 0 +RAB36 UCSF GRCh37 22 23503121 23503121 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.236,1000g2011may_all_0.3625,snp132_rs5759611 P05_Rec Untested WXS Illumina HiSeq 55 35 46 1 ENST00000263116.2:c.873G>A p.Ser291= p.S291= ENST00000263116 NM_004914.2 291 tcG/tcA 0 +RAB3D UCSF GRCh37 19 11436176 11436176 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 98 55 42 0 ENST00000222120.3:c.558G>A p.Lys186= p.K186= ENST00000222120 NM_004283.3 186 aaG/aaA 0 +RAB3GAP1 UCSF GRCh37 2 135926128 135926128 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 65 79 0 ENST00000442034.1:c.2744C>T p.Thr915Ile p.T915I ENST00000442034 NM_001172435.1 915 aCt/aTt 0 +RAB5C UCSF GRCh37 17 40280691 40280691 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 44 80 0 ENST00000547517.1:c.393C>T p.Ile131= p.I131= ENST00000547517 NM_001252039.1 131 atC/atT 0 +RAD18 UCSF GRCh37 3 8940660 8940660 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 18 49 0 ENST00000264926.2:c.1240G>A p.Glu414Lys p.E414K ENST00000264926 NM_020165.3 414 Gaa/Aaa 0 +RAD18 UCSF GRCh37 3 8940694 8940694 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 106 16 54 0 ENST00000264926.2:c.1206T>C p.Phe402= p.F402= ENST00000264926 NM_020165.3 402 ttT/ttC 0 +RANBP10 UCSF GRCh37 16 67763929 67763929 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 28 28 0 ENST00000317506.3:c.910G>A p.Glu304Lys p.E304K ENST00000317506 NM_020850.1 304 Gag/Aag 0 +RANBP17 UCSF GRCh37 5 170380687 170380687 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 6 14 46 0 ENST00000523189.1:c.1555G>A p.Asp519Asn p.D519N ENST00000523189 NM_022897.3 519 Gat/Aat 0 +RANGAP1 UCSF GRCh37 22 41660817 41660817 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 39 58 0 ENST00000455915.2:c.331G>A p.Gly111Arg p.G111R ENST00000455915 111 Ggg/Agg 0 +RASSF2 UCSF GRCh37 20 4776541 4776541 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 37 45 0 ENST00000379400.3:c.207G>A p.Gln69= p.Q69= ENST00000379400 NM_014737.2 69 caG/caA 0 +RB1CC1 UCSF GRCh37 8 53573509 53573509 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 22 52 0 ENST00000025008.5:c.1604G>A p.Arg535Lys p.R535K ENST00000025008 NM_014781.4 535 aGg/aAg 0 +RB1CC1 UCSF GRCh37 8 53569395 53569395 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 137 68 129 0 ENST00000025008.5:c.2994G>A p.Arg998= p.R998= ENST00000025008 NM_014781.4 998 agG/agA 0 +RBAK UCSF GRCh37 7 5097359 5097359 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 29 104 0 ENST00000396904.2:c.187G>A p.Gly63Arg p.G63R ENST00000396904 NM_001204513.1 63 Gga/Aga 0 +RBL2 UCSF GRCh37 16 53487653 53487653 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 44 47 0 ENST00000262133.6:c.964C>T p.Leu322= p.L322= ENST00000262133 NM_005611.3 322 Cta/Tta 0 +RBM14 UCSF GRCh37 11 66392419 66392419 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 105 86 0 ENST00000310137.4:c.1072G>A p.Val358Ile p.V358I ENST00000310137 NM_006328.3 358 Gtt/Att 0 +RBP2 UCSF GRCh37 3 139195235 139195235 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 22 34 0 ENST00000232217.2:c.67G>A p.Ala23Thr p.A23T ENST00000232217 NM_004164.2 23 Gcc/Acc 0 +RBP3 UCSF GRCh37 10 48390586 48390586 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 56 40 0 ENST00000224600.4:c.292C>T p.Pro98Ser p.P98S ENST00000224600 NM_002900.2 98 Cct/Tct 0 +RBPJL UCSF GRCh37 20 43936831 43936831 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 44 30 0 ENST00000343694.3:c.71G>A p.Arg24Lys p.R24K ENST00000343694 NM_001281449.1 24 aGa/aAa 0 +RCCD1 UCSF GRCh37 15 91504989 91504989 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 43 65 0 ENST00000394258.2:c.1121G>A p.Gly374Glu p.G374E ENST00000394258 NM_033544.2 374 gGg/gAg 0 +REEP4 UCSF GRCh37 8 21997031 21997031 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 16 22 0 ENST00000306306.3:c.315G>A p.Ala105= p.A105= ENST00000306306 NM_025232.2 105 gcG/gcA 0 +RELN UCSF GRCh37 7 103183256 103183256 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 95 69 97 0 ENST00000428762.1:c.6593C>T p.Ser2198Phe p.S2198F ENST00000428762 NM_005045.3 2198 tCt/tTt 0 +RELN UCSF GRCh37 7 103163894 103163894 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 145 56 131 0 ENST00000428762.1:c.7434G>A p.Gly2478= p.G2478= ENST00000428762 NM_005045.3 2478 ggG/ggA 0 +REXO1L1 UCSF GRCh37 8 86575271 86575271 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 8 16 14 0 ENST00000379010.2:c.456G>A p.Gln152= p.Q152= ENST00000379010 NM_172239.4 152 caG/caA 0 +RFWD3 UCSF GRCh37 16 74685996 74685996 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 37 79 0 ENST00000361070.4:c.543C>T p.Tyr181= p.Y181= ENST00000361070 NM_018124.3 181 taC/taT 0 +RFX3 UCSF GRCh37 9 3225266 3225266 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 26 43 0 ENST00000382004.3:c.2026G>A p.Val676Ile p.V676I ENST00000382004 NM_134428.1 676 Gta/Ata 0 +RFX8 UCSF GRCh37 2 102019210 102019210 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 60 25 37 0 ENST00000428343.1:c.933C>T p.Ser311= p.S311= ENST00000428343 NM_001145664.1 311 tcC/tcT 0 +RGNEF UCSF GRCh37 5 73142300 73142300 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 51 85 0 ENST00000545377.1:c.1635G>A p.Lys545= p.K545= ENST00000545377 NM_001080479.2 545 aaG/aaA 0 +RGPD4 UCSF GRCh37 2 108489331 108489331 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 110 63 230 0 ENST00000408999.3:c.4871C>T p.Ser1624Phe p.S1624F ENST00000408999 NM_182588.2 1624 tCc/tTc 0 +RGS12 UCSF GRCh37 4 3432488 3432488 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 14 10 0 ENST00000344733.5:c.3920C>T p.Ser1307Phe p.S1307F ENST00000344733 NM_198229.2 1307 tCc/tTc 0 +RHBDF1 UCSF GRCh37 16 108500 108500 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 123 79 86 0 ENST00000262316.6:c.2407C>T p.Gln803Ter p.Q803* ENST00000262316 NM_022450.3 803 Cag/Tag 0 +RHBDF2 UCSF GRCh37 17 74469754 74469754 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 30 7 12 0 ENST00000313080.4:c.1796C>T p.Pro599Leu p.P599L ENST00000313080 NM_024599.5 599 cCc/cTc 0 +RHO UCSF GRCh37 3 129252456 129252456 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 133 47 76 0 ENST00000296271.3:c.942G>A p.Arg314= p.R314= ENST00000296271 NM_000539.3 314 cgG/cgA 0 +RHOBTB3 UCSF GRCh37 5 95088031 95088031 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 61 59 0 ENST00000379982.3:c.659G>A p.Arg220Lys p.R220K ENST00000379982 NM_014899.3 220 aGa/aAa 0 +RICTOR UCSF GRCh37 5 39003668 39003668 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 23 46 0 ENST00000357387.3:c.252C>T p.Ile84= p.I84= ENST00000357387 NM_152756.3 84 atC/atT 0 +RIF1 UCSF GRCh37 2 152331414 152331414 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 14 34 0 ENST00000243326.5:c.7248C>T p.Asn2416= p.N2416= ENST00000243326 2416 aaC/aaT 0 +RIMBP2 UCSF GRCh37 12 130929794 130929794 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 20 45 0 ENST00000261655.4:c.551C>T p.Pro184Leu p.P184L ENST00000261655 NM_015347.4 184 cCg/cTg 0 +RIOK2 UCSF GRCh37 5 96503335 96503335 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 112 67 109 0 ENST00000283109.3:c.1233C>T p.Asn411= p.N411= ENST00000283109 NM_018343.2 411 aaC/aaT 0 +RLTPR UCSF GRCh37 16 67679506 67679506 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 47 30 0 ENST00000334583.6:c.104G>A p.Gly35Glu p.G35E ENST00000334583 NM_001013838.1 35 gGg/gAg 0 +RND3 UCSF GRCh37 2 151328193 151328193 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 23 56 0 ENST00000375734.2:c.431G>A p.Ser144Asn p.S144N ENST00000375734 NM_001254738.1 144 aGt/aAt 0 +RNF113B UCSF GRCh37 13 98829236 98829236 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 50 14 0 ENST00000267291.6:c.255G>A p.Ala85= p.A85= ENST00000267291 NM_178861.4 85 gcG/gcA 0 +RNF114 UCSF GRCh37 20 48565871 48565871 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 37 46 0 ENST00000244061.2:c.600G>A p.Arg200= p.R200= ENST00000244061 NM_018683.3 200 cgG/cgA 0 +RNF123 UCSF GRCh37 3 49737668 49737668 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 18 21 0 ENST00000327697.6:c.993G>A p.Val331= p.V331= ENST00000327697 NM_022064.3 331 gtG/gtA 0 +RNF123 UCSF GRCh37 3 49743495 49743495 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 13 36 0 ENST00000327697.6:c.2385G>A p.Lys795= p.K795= ENST00000327697 NM_022064.3 795 aaG/aaA 0 +RNF13 UCSF GRCh37 3 149677842 149677842 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 22 67 0 ENST00000344229.3:c.701-1G>A p.X234_splice ENST00000344229 NM_007282.4 0 +RNF139 UCSF GRCh37 8 125498715 125498715 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 54 97 0 ENST00000303545.3:c.825C>T p.Asp275= p.D275= ENST00000303545 NM_007218.3 275 gaC/gaT 0 +RNF150 UCSF GRCh37 4 141870520 141870520 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 37 102 0 ENST00000515673.2:c.742C>T p.Leu248= p.L248= ENST00000515673 248 Ctg/Ttg 0 +RNF150 UCSF GRCh37 4 141888968 141888968 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 70 113 0 ENST00000515673.2:c.544C>T p.Leu182= p.L182= ENST00000515673 182 Ctg/Ttg 0 +RNF157 UCSF GRCh37 17 74158020 74158020 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 47 69 0 ENST00000269391.6:c.856G>A p.Asp286Asn p.D286N ENST00000269391 NM_052916.2 286 Gac/Aac 0 +RNF17 UCSF GRCh37 13 25428150 25428150 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 41 84 0 ENST00000255324.5:c.3478C>T p.Gln1160Ter p.Q1160* ENST00000255324 NM_031277.2 1160 Cag/Tag 0 +RNF180 UCSF GRCh37 5 63626112 63626112 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 29 52 0 ENST00000389100.4:c.1458G>A p.Leu486= p.L486= ENST00000389100 NM_001113561.1 486 ttG/ttA 0 +RNF2 UCSF GRCh37 1 185069003 185069003 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0015 P05_Rec Untested WXS Illumina HiSeq 88 53 57 0 ENST00000367510.3:c.818G>A p.Arg273Gln p.R273Q ENST00000367510 NM_007212.3 273 cGa/cAa 0 +RNF213 UCSF GRCh37 17 78323679 78323679 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 48 54 0 ENST00000582970.1:c.10061C>T p.Thr3354Ile p.T3354I ENST00000582970 NM_001256071.1 3354 aCc/aTc 0 +RNF213 UCSF GRCh37 17 78293052 78293052 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 138 65 86 0 ENST00000582970.1:c.2964G>A p.Glu988= p.E988= ENST00000582970 NM_001256071.1 988 gaG/gaA 0 +RNF214 UCSF GRCh37 11 117153912 117153912 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 48 20 51 0 ENST00000531452.1:c.2032G>A p.Val678Ile p.V678I ENST00000531452 NM_001077239.1 678 Gta/Ata 0 +RNF220 UCSF GRCh37 1 44877999 44877999 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 226 123 212 0 ENST00000355387.2:c.230G>A p.Gly77Asp p.G77D ENST00000355387 77 gGt/gAt 0 +RNF24 UCSF GRCh37 20 3928926 3928926 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 31 25 0 ENST00000432261.2:c.207G>A p.Arg69= p.R69= ENST00000432261 69 agG/agA 0 +RNF40 UCSF GRCh37 16 30776630 30776630 + synonymous_variant Silent SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 82 50 64 0 ENST00000324685.6:c.900G>C p.Leu300= p.L300= ENST00000324685 NM_014771.3 300 ctG/ctC 0 +RNF5 UCSF GRCh37 6 32148052 32148052 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 161 76 167 0 ENST00000375094.3:c.492C>T p.Ser164= p.S164= ENST00000375094 NM_006913.3 164 tcC/tcT 0 +RNGTT UCSF GRCh37 6 89388107 89388107 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 37 71 0 ENST00000369485.4:c.1471G>A p.Val491Ile p.V491I ENST00000369485 NM_003800.3 491 Gtt/Att 0 +ROS1 UCSF GRCh37 6 117622266 117622266 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 42 82 0 ENST00000368508.3:c.6604C>T p.Pro2202Ser p.P2202S ENST00000368508 NM_002944.2 2202 Ccc/Tcc 0 +RP1 UCSF GRCh37 8 55534714 55534714 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 40 26 44 0 ENST00000220676.1:c.653C>G p.Ala218Gly p.A218G ENST00000220676 NM_006269.1 218 gCt/gGt 0 +RP1L1 UCSF GRCh37 8 10466129 10466129 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 194 108 182 0 ENST00000382483.3:c.5479G>A p.Gly1827Arg p.G1827R ENST00000382483 NM_178857.5 1827 Gga/Aga 0 +RP1L1 UCSF GRCh37 8 10464965 10464965 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 80 109 0 ENST00000382483.3:c.6643C>T p.Pro2215Ser p.P2215S ENST00000382483 NM_178857.5 2215 Ccg/Tcg 0 +RP2 UCSF GRCh37 X 46713289 46713289 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 47 106 0 ENST00000218340.3:c.481G>A p.Asp161Asn p.D161N ENST00000218340 NM_006915.2 161 Gat/Aat 0 +RPIA UCSF GRCh37 2 88991451 88991451 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 9 8 8 0 ENST00000283646.4:c.235G>A p.Glu79Lys p.E79K ENST00000283646 NM_144563.2 79 Gag/Aag 0 +RPL10A UCSF GRCh37 6 35437987 35437987 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 30 92 0 ENST00000322203.6:c.342G>A p.Glu114= p.E114= ENST00000322203 NM_007104.4 114 gaG/gaA 0 +RPL13 UCSF GRCh37 16 89628061 89628061 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 31 34 0 ENST00000393099.3:c.322G>A p.Glu108Lys p.E108K ENST00000393099 NM_033251.2 108 Gag/Aag 0 +RPP21 UCSF GRCh37 6 30314507 30314507 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 150 84 121 0 ENST00000433076.2:c.409C>T p.Pro137Ser p.P137S ENST00000433076 NM_001199121.1 137 Ccc/Tcc 0 +RPS6KC1 UCSF GRCh37 1 213251046 213251046 + synonymous_variant Silent SNP A A T NOVEL P05_Rec Untested WXS Illumina HiSeq 82 29 43 0 ENST00000366960.3:c.150A>T p.Val50= p.V50= ENST00000366960 NM_012424.3 50 gtA/gtT 0 +RPS8 UCSF GRCh37 1 45243785 45243785 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 12 7 14 0 ENST00000396651.3:c.501G>A p.Gln167= p.Q167= ENST00000396651 167 caG/caA 0 +RPTOR UCSF GRCh37 17 78704465 78704465 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 44 6 54 0 ENST00000306801.3:c.613T>C p.Ser205Pro p.S205P ENST00000306801 NM_020761.2 205 Tcc/Ccc 0 +RRAGB UCSF GRCh37 X 55757830 55757830 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 14 21 0 ENST00000262850.7:c.411C>T p.Ser137= p.S137= ENST00000262850 NM_016656.3 137 agC/agT 0 +RRN3 UCSF GRCh37 16 15180303 15180303 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 53 120 0 ENST00000198767.6:c.261G>A p.Gln87= p.Q87= ENST00000198767 NM_018427.3 87 caG/caA 0 +RSC1A1 UCSF GRCh37 1 15987061 15987061 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 44 61 0 ENST00000345034.1:c.698G>A p.Ser233Asn p.S233N ENST00000345034 NM_006511.1 233 aGt/aAt 0 +RTEL1 UCSF GRCh37 20 62292654 62292654 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 25 21 0 ENST00000508582.2:c.106G>A p.Val36Met p.V36M ENST00000508582 36 Gtg/Atg 0 +RTN1 UCSF GRCh37 14 60212941 60212941 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 37 108 0 ENST00000267484.5:c.500G>A p.Gly167Glu p.G167E ENST00000267484 NM_021136.2 167 gGa/gAa 0 +RTTN UCSF GRCh37 18 67781767 67781767 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 41 78 0 ENST00000255674.6:c.3597C>T p.Ile1199= p.I1199= ENST00000255674 NM_173630.3 1199 atC/atT 0 +RUNDC3A UCSF GRCh37 17 42390577 42390577 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 41 56 0 ENST00000426726.3:c.329G>A p.Ser110Asn p.S110N ENST00000426726 NM_001144825.1 110 aGc/aAc 0 +RXFP2 UCSF GRCh37 13 32339202 32339202 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 32 41 0 ENST00000298386.2:c.348C>T p.Asp116= p.D116= ENST00000298386 NM_130806.3 116 gaC/gaT 0 +RXRG UCSF GRCh37 1 165398050 165398050 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 17 27 0 ENST00000359842.5:c.203C>T p.Ser68Phe p.S68F ENST00000359842 NM_001256570.1 68 tCt/tTt 0 +RYR1 UCSF GRCh37 19 39013693 39013693 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 33 33 0 ENST00000359596.3:c.10285C>T p.Pro3429Ser p.P3429S ENST00000359596 3429 Ccc/Tcc 0 +RYR1 UCSF GRCh37 19 38956832 38956832 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 14 14 0 ENST00000359596.3:c.2972G>A p.Gly991Glu p.G991E ENST00000359596 991 gGg/gAg 0 +RYR1 UCSF GRCh37 19 38968400 38968400 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 12 20 0 ENST00000359596.3:c.4344G>A p.Trp1448Ter p.W1448* ENST00000359596 1448 tgG/tgA 0 +RYR2 UCSF GRCh37 1 237954787 237954787 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 49 81 0 ENST00000366574.2:c.13535C>T p.Ala4512Val p.A4512V ENST00000366574 NM_001035.2 4512 gCt/gTt 0 +SAC3D1 UCSF GRCh37 11 64812037 64812037 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 102 38 34 0 ENST00000398846.1:c.915G>A p.Glu305= p.E305= ENST00000398846 NM_013299.3 305 gaG/gaA 0 +SAFB2 UCSF GRCh37 19 5587911 5587911 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 18 8 9 0 ENST00000252542.4:c.2606G>A p.Gly869Asp p.G869D ENST00000252542 NM_014649.2 869 gGc/gAc 0 +SALL1 UCSF GRCh37 16 51174240 51174240 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 149 64 47 0 ENST00000251020.4:c.1893C>T p.Thr631= p.T631= ENST00000251020 NM_002968.2 631 acC/acT 0 +SAMD11 UCSF GRCh37 1 865642 865642 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 12 8 12 0 ENST00000598827.1:c.100C>T p.Pro34Ser p.P34S ENST00000598827 34 Ccc/Tcc 0 +SAMD4A UCSF GRCh37 14 55169174 55169174 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 61 91 0 ENST00000392067.3:c.591G>A p.Gly197= p.G197= ENST00000392067 NM_015589.5 197 ggG/ggA 0 +SAP25 UCSF GRCh37 7 100170545 100170545 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 8 9 0 ENST00000538735.1:c.155G>A p.Gly52Asp p.G52D ENST00000538735 NM_001168682.1 52 gGt/gAt 0 +SART1 UCSF GRCh37 11 65743872 65743872 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 25 11 0 ENST00000312397.5:c.1579G>A p.Glu527Lys p.E527K ENST00000312397 NM_005146.4 527 Gag/Aag 0 +SART1 UCSF GRCh37 11 65744536 65744536 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 37 18 0 ENST00000312397.5:c.1909G>A p.Gly637Arg p.G637R ENST00000312397 NM_005146.4 637 Ggg/Agg 0 +SATB2 UCSF GRCh37 2 200188589 200188589 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 24 58 0 ENST00000417098.1:c.1479G>A p.Gln493= p.Q493= ENST00000417098 NM_001172509.1 493 caG/caA 0 +SBDS UCSF GRCh37 7 66459269 66459269 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 189 57 109 0 ENST00000246868.2:c.188G>A p.Gly63Asp p.G63D ENST00000246868 NM_016038.2 63 gGt/gAt 0 +SBNO1 UCSF GRCh37 12 123794257 123794257 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 138 45 90 0 ENST00000420886.2:c.3442G>A p.Asp1148Asn p.D1148N ENST00000420886 NM_001167856.1 1148 Gat/Aat 0 +SCAPER UCSF GRCh37 15 76914126 76914126 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 31 45 0 ENST00000563290.1:c.2690C>T p.Ser897Phe p.S897F ENST00000563290 897 tCt/tTt 0 +SCARB1 UCSF GRCh37 12 125267329 125267329 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 25 59 0 ENST00000261693.6:c.1430G>A p.Ser477Asn p.S477N ENST00000261693 NM_005505.4 477 aGt/aAt 0 +SCML2 UCSF GRCh37 X 18264916 18264916 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 88 129 0 ENST00000251900.4:c.1603C>T p.Pro535Ser p.P535S ENST00000251900 NM_006089.2 535 Ccc/Tcc 0 +SCML4 UCSF GRCh37 6 108068037 108068037 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 60 40 0 ENST00000369020.3:c.343G>A p.Val115Met p.V115M ENST00000369020 NM_198081.3 115 Gtg/Atg 0 +SCN11A UCSF GRCh37 3 38936098 38936098 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 157 71 116 0 ENST00000302328.3:c.2761G>A p.Glu921Lys p.E921K ENST00000302328 NM_014139.2 921 Gag/Aag 0 +SCN4A UCSF GRCh37 17 62036654 62036654 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 15 32 0 ENST00000435607.1:c.1990G>A p.Gly664Arg p.G664R ENST00000435607 NM_000334.4 664 Gga/Aga 0 +SCN4A UCSF GRCh37 17 62038634 62038634 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 192 96 110 0 ENST00000435607.1:c.1764C>T p.Ile588= p.I588= ENST00000435607 NM_000334.4 588 atC/atT 0 +SCN7A UCSF GRCh37 2 167289148 167289148 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 130 63 65 0 ENST00000409855.1:c.2272G>A p.Gly758Arg p.G758R ENST00000409855 NM_002976.3 758 Gga/Aga 0 +SCN7A UCSF GRCh37 2 167301309 167301309 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 108 68 121 0 ENST00000409855.1:c.1589G>A p.Ser530Asn p.S530N ENST00000409855 NM_002976.3 530 aGt/aAt 0 +SCN7A UCSF GRCh37 2 167284406 167284406 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 52 67 0 ENST00000409855.1:c.2745G>A p.Lys915= p.K915= ENST00000409855 NM_002976.3 915 aaG/aaA 0 +SCUBE1 UCSF GRCh37 22 43614335 43614335 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 56 67 60 0 ENST00000360835.4:c.1817C>T p.Ala606Val p.A606V ENST00000360835 NM_173050.3 606 gCc/gTc 0 +SCYL1 UCSF GRCh37 11 65304221 65304221 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 110 47 77 0 ENST00000270176.5:c.1816G>A p.Gly606Arg p.G606R ENST00000270176 NM_020680.3 606 Gga/Aga 0 +SDHA UCSF GRCh37 5 224511 224511 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 204 102 187 0 ENST00000264932.6:c.187G>A p.Asp63Asn p.D63N ENST00000264932 NM_004168.2 63 Gat/Aat 0 +SDK1 UCSF GRCh37 7 4273021 4273021 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 19 31 0 ENST00000404826.2:c.5962G>A p.Glu1988Lys p.E1988K ENST00000404826 NM_152744.3 1988 Gag/Aag 0 +SDK2 UCSF GRCh37 17 71434243 71434243 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0085 P05_Rec Untested WXS Illumina HiSeq 21 9 17 0 ENST00000392650.3:c.776C>T p.Ser259Leu p.S259L ENST00000392650 NM_001144952.1 259 tCg/tTg 0 +SEC16B UCSF GRCh37 1 177913769 177913769 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 153 103 171 0 ENST00000308284.6:c.1808C>T p.Ala603Val p.A603V ENST00000308284 NM_033127.2 603 gCa/gTa 0 +SEC23A UCSF GRCh37 14 39532604 39532604 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 20 35 0 ENST00000307712.6:c.1322G>A p.Gly441Asp p.G441D ENST00000307712 NM_006364.2 441 gGt/gAt 0 +SEC24B UCSF GRCh37 4 110434905 110434905 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 36 74 0 ENST00000265175.5:c.1906C>T p.Pro636Ser p.P636S ENST00000265175 NM_006323.2 636 Cct/Tct 0 +SEC31A UCSF GRCh37 4 83772730 83772730 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 22 60 0 ENST00000395310.2:c.2182C>T p.Arg728Ter p.R728* ENST00000395310 NM_001077207.2 728 Cga/Tga 0 +SEL1L UCSF GRCh37 14 81993276 81993276 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 41 79 0 ENST00000336735.4:c.141C>T p.Asp47= p.D47= ENST00000336735 NM_005065.5 47 gaC/gaT 0 +SEL1L2 UCSF GRCh37 20 13869127 13869127 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 24 34 0 ENST00000378072.5:c.581G>A p.Gly194Glu p.G194E ENST00000378072 NM_001271539.1 194 gGa/gAa 0 +SEL1L3 UCSF GRCh37 4 25759371 25759371 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 17 35 0 ENST00000399878.3:c.3125C>T p.Ser1042Phe p.S1042F ENST00000399878 NM_015187.3 1042 tCc/tTc 0 +SELE UCSF GRCh37 1 169697058 169697058 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 119 17 103 0 ENST00000333360.7:c.1290C>T p.Cys430= p.C430= ENST00000333360 NM_000450.2 430 tgC/tgT 0 +SEMA3A UCSF GRCh37 7 83590932 83590932 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 151 62 113 0 ENST00000265362.4:c.2071A>C p.Met691Leu p.M691L ENST00000265362 NM_006080.2 691 Atg/Ctg 0 +SEMA3C UCSF GRCh37 7 80418734 80418734 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 50 106 0 ENST00000265361.3:c.1242C>T p.Ile414= p.I414= ENST00000265361 NM_006379.3 414 atC/atT 0 +SEMA3D UCSF GRCh37 7 84751156 84751156 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 27 64 0 ENST00000284136.6:c.52C>T p.Leu18Phe p.L18F ENST00000284136 NM_152754.2 18 Ctt/Ttt 0 +SEMA3F UCSF GRCh37 3 50211247 50211247 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 12 25 0 ENST00000002829.3:c.134C>T p.Ala45Val p.A45V ENST00000002829 NM_004186.3 45 gCc/gTc 0 +SEMA3F UCSF GRCh37 3 50223726 50223726 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 10 13 0 ENST00000002829.3:c.1758G>A p.Arg586= p.R586= ENST00000002829 NM_004186.3 586 cgG/cgA 0 +SEMA3G UCSF GRCh37 3 52474455 52474455 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 15 14 0 ENST00000231721.2:c.1081G>A p.Asp361Asn p.D361N ENST00000231721 NM_020163.1 361 Gat/Aat 0 +SEMA4D UCSF GRCh37 9 91996225 91996225 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 20 9 0 ENST00000450295.1:c.1483G>A p.Val495Met p.V495M ENST00000450295 495 Gtg/Atg 0 +SEMG2 UCSF GRCh37 20 43851472 43851472 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 42 88 0 ENST00000372769.3:c.1199G>A p.Gly400Asp p.G400D ENST00000372769 NM_003008.2 400 gGc/gAc 0 +SERPINA4 UCSF GRCh37 14 95033368 95033368 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 26 54 0 ENST00000557004.1:c.711G>A p.Glu237= p.E237= ENST00000557004 237 gaG/gaA 0 +SERPINB11 UCSF GRCh37 18 61377551 61377551 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 48 119 0 ENST00000544088.1:c.124G>A p.Val42Ile p.V42I ENST00000544088 NM_080475.2 42 Gtc/Atc 0 +SERPINB2 UCSF GRCh37 18 61558714 61558714 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 27 48 1 ENST00000457692.1:c.36C>T p.Ala12= p.A12= ENST00000457692 NM_001143818.1 12 gcC/gcT 0 +SERPINB6 UCSF GRCh37 6 2948720 2948720 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 50 101 0 ENST00000380520.1:c.943G>A p.Val315Ile p.V315I ENST00000380520 315 Gtc/Atc 0 +SERPINE3 UCSF GRCh37 13 51929249 51929249 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 84 94 0 ENST00000521255.1:c.970C>T p.Pro324Ser p.P324S ENST00000521255 NM_001101320.1 324 Cca/Tca 0 +SETD1A UCSF GRCh37 16 30990750 30990750 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 41 17 17 0 ENST00000262519.8:c.3643G>A p.Ala1215Thr p.A1215T ENST00000262519 NM_014712.1 1215 Gca/Aca 0 +SETD5 UCSF GRCh37 3 9483315 9483315 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.004,1000g2011may_all_0.01369,snp132_rs17050347 P05_Rec Untested WXS Illumina HiSeq 293 109 148 0 ENST00000402198.1:c.849G>A p.Arg283= p.R283= ENST00000402198 NM_001080517.1 283 cgG/cgA 0 +SETX UCSF GRCh37 9 135221755 135221755 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 24 54 0 ENST00000224140.5:c.281G>A p.Gly94Glu p.G94E ENST00000224140 NM_015046.5 94 gGa/gAa 0 +SEZ6L2 UCSF GRCh37 16 29900010 29900010 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 24 13 13 0 ENST00000308713.5:c.890C>T p.Ala297Val p.A297V ENST00000308713 NM_001114099.2 297 gCc/gTc 0 +SF3A3 UCSF GRCh37 1 38447484 38447484 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 45 71 0 ENST00000373019.4:c.469-1G>A p.X157_splice ENST00000373019 NM_006802.2 0 +SF3B3 UCSF GRCh37 16 70588362 70588362 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 160 48 108 0 ENST00000302516.5:c.1416C>T p.Ala472= p.A472= ENST00000302516 NM_012426.4 472 gcC/gcT 0 +SFI1 UCSF GRCh37 22 32011115 32011115 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 7 10 0 ENST00000400288.2:c.3150C>T p.Ala1050= p.A1050= ENST00000400288 NM_001007467.2 1050 gcC/gcT 0 +SFMBT1 UCSF GRCh37 3 52941713 52941713 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 31 59 0 ENST00000394752.3:c.1943G>A p.Gly648Glu p.G648E ENST00000394752 NM_016329.3 648 gGg/gAg 0 +SGK2 UCSF GRCh37 20 42203554 42203554 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 20 12 29 0 ENST00000341458.4:c.783G>A p.Leu261= p.L261= ENST00000341458 NM_016276.3 261 ttG/ttA 0 +SGSH UCSF GRCh37 17 78185869 78185869 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 25 18 0 ENST00000326317.6:c.949+1G>A p.X317_splice ENST00000326317 NM_000199.3 0 +SH3BP2 UCSF GRCh37 4 2831619 2831619 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 58 40 0 ENST00000503393.2:c.1157G>A p.Arg386Lys p.R386K ENST00000503393 NM_001145856.1 386 aGa/aAa 0 +SH3D21 UCSF GRCh37 1 36785572 36785572 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 39 83 0 ENST00000453908.2:c.1308G>A p.Glu436= p.E436= ENST00000453908 NM_001162530.1 436 gaG/gaA 0 +SHISA6 UCSF GRCh37 17 11145222 11145222 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 102 18 38 0 ENST00000441885.3:c.483G>A p.Pro161= p.P161= ENST00000441885 NM_207386.3 161 ccG/ccA 0 +SHISA9 UCSF GRCh37 16 13002407 13002407 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 30 79 0 ENST00000424107.3:c.563+5923G>A *188* ENST00000424107 0 +SHROOM3 UCSF GRCh37 4 77357299 77357299 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 96 56 114 0 ENST00000296043.6:c.94C>T p.Leu32= p.L32= ENST00000296043 NM_020859.3 32 Ctg/Ttg 0 +SHROOM3 UCSF GRCh37 4 77676169 77676169 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 38 61 0 ENST00000296043.6:c.4533G>A p.Arg1511= p.R1511= ENST00000296043 NM_020859.3 1511 agG/agA 0 +SIAH3 UCSF GRCh37 13 46357545 46357545 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 32 31 35 0 ENST00000400405.2:c.783G>A p.Glu261= p.E261= ENST00000400405 NM_198849.2 261 gaG/gaA 0 +SIDT2 UCSF GRCh37 11 117052778 117052778 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 11 32 0 ENST00000324225.4:c.473C>T p.Thr158Ile p.T158I ENST00000324225 NM_001040455.1 158 aCt/aTt 0 +SIDT2 UCSF GRCh37 11 117063895 117063895 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 233 176 216 0 ENST00000324225.4:c.2132C>T p.Pro711Leu p.P711L ENST00000324225 NM_001040455.1 711 cCc/cTc 0 +SIGLEC1 UCSF GRCh37 20 3673728 3673728 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 18 11 0 ENST00000344754.4:c.3559C>T p.Gln1187Ter p.Q1187* ENST00000344754 NM_023068.3 1187 Cag/Tag 0 +SIGLEC5 UCSF GRCh37 19 52132855 52132855 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 5 12 0 ENST00000429354.3:c.456G>A p.Glu152= p.E152= ENST00000429354 152 gaG/gaA 0 +SIK1 UCSF GRCh37 21 44841865 44841865 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 28 48 0 ENST00000270162.6:c.326G>A p.Gly109Glu p.G109E ENST00000270162 NM_173354.3 109 gGa/gAa 0 +SIK3 UCSF GRCh37 11 116746647 116746647 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 52 76 0 ENST00000292055.4:c.1000C>T p.Leu334= p.L334= ENST00000292055 NM_025164.3 334 Ctg/Ttg 0 +SIPA1L3 UCSF GRCh37 19 38579470 38579470 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 43 31 52 0 ENST00000222345.6:c.1644G>A p.Arg548= p.R548= ENST00000222345 NM_015073.1 548 agG/agA 0 +SIRT2 UCSF GRCh37 19 39380548 39380548 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 33 60 0 ENST00000249396.7:c.322G>A p.Glu108Lys p.E108K ENST00000249396 NM_012237.3 108 Gag/Aag 0 +SIRT4 UCSF GRCh37 12 120750410 120750410 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 11 56 0 ENST00000202967.4:c.649G>A p.Val217Ile p.V217I ENST00000202967 NM_012240.2 217 Gtc/Atc 0 +SKAP2 UCSF GRCh37 7 26709795 26709795 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 12 35 0 ENST00000345317.2:c.1004G>A p.Gly335Asp p.G335D ENST00000345317 NM_003930.3 335 gGc/gAc 0 +SKIV2L2 UCSF GRCh37 5 54639158 54639158 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 33 76 0 ENST00000230640.5:c.782-1G>A p.X261_splice ENST00000230640 NM_015360.4 0 +SLC12A9 UCSF GRCh37 7 100454542 100454542 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 95 25 32 0 ENST00000354161.3:c.501C>T p.Asn167= p.N167= ENST00000354161 NM_020246.3 167 aaC/aaT 0 +SLC15A2 UCSF GRCh37 3 121658311 121658311 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 58 75 0 ENST00000489711.1:c.1877C>T p.Ser626Phe p.S626F ENST00000489711 NM_021082.3 626 tCt/tTt 0 +SLC16A14 UCSF GRCh37 2 230910924 230910924 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 31 72 0 ENST00000295190.4:c.918G>A p.Gly306= p.G306= ENST00000295190 NM_152527.4 306 ggG/ggA 0 +SLC18A1 UCSF GRCh37 8 20036854 20036854 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 51 85 0 ENST00000440926.1:c.266C>T p.Thr89Ile p.T89I ENST00000440926 NM_001135691.2 89 aCc/aTc 0 +SLC24A6 UCSF GRCh37 12 113756781 113756781 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 19 31 0 ENST00000552014.1:c.790C>T p.Pro264Ser p.P264S ENST00000552014 264 Cca/Tca 0 +SLC25A19 UCSF GRCh37 17 73279605 73279605 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 8 28 0 ENST00000402418.3:c.358G>A p.Val120Met p.V120M ENST00000402418 120 Gtg/Atg 0 +SLC26A3 UCSF GRCh37 7 107416971 107416971 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 14 64 0 ENST00000340010.5:c.1603G>A p.Val535Met p.V535M ENST00000340010 NM_000111.2 535 Gtg/Atg 0 +SLC26A6 UCSF GRCh37 3 48666082 48666082 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 67 41 68 0 ENST00000395550.2:c.1665G>A p.Glu555= p.E555= ENST00000395550 555 gaG/gaA 0 +SLC26A9 UCSF GRCh37 1 205889351 205889351 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 21 47 0 ENST00000367134.2:c.2063C>T p.Ser688Phe p.S688F ENST00000367134 NM_134325.2 688 tCc/tTc 0 +SLC27A4 UCSF GRCh37 9 131107546 131107546 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 128 32 22 0 ENST00000300456.4:c.274G>A p.Ala92Thr p.A92T ENST00000300456 NM_005094.3 92 Gcc/Acc 0 +SLC28A3 UCSF GRCh37 9 86912910 86912910 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 62 123 0 ENST00000376238.4:c.694G>A p.Gly232Arg p.G232R ENST00000376238 NM_001199633.1 232 Gga/Aga 0 +SLC2A2 UCSF GRCh37 3 170716107 170716107 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 22 65 0 ENST00000314251.3:c.1249C>T p.Pro417Ser p.P417S ENST00000314251 NM_001278659.1 417 Ccg/Tcg 0 +SLC2A5 UCSF GRCh37 1 9098964 9098964 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 5 19 0 ENST00000377424.4:c.1021C>T p.Arg341Trp p.R341W ENST00000377424 NM_003039.2 341 Cgg/Tgg 0 +SLC30A8 UCSF GRCh37 8 118165280 118165280 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 28 37 0 ENST00000456015.2:c.369G>A p.Leu123= p.L123= ENST00000456015 NM_173851.2 123 ttG/ttA 0 +SLC33A1 UCSF GRCh37 3 155571041 155571041 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 20 21 0 ENST00000392845.3:c.746C>T p.Pro249Leu p.P249L ENST00000392845 249 cCt/cTt 0 +SLC35B2 UCSF GRCh37 6 44222530 44222530 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 37 52 0 ENST00000393812.3:c.1212C>T p.Ala404= p.A404= ENST00000393812 NM_178148.2 404 gcC/gcT 0 +SLC35F5 UCSF GRCh37 2 114493359 114493359 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 17 13 0 ENST00000245680.2:c.827C>T p.Thr276Ile p.T276I ENST00000245680 NM_025181.2 276 aCt/aTt 0 +SLC35G6 UCSF GRCh37 17 7385318 7385318 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 37 24 0 ENST00000412468.2:c.15C>T p.His5= p.H5= ENST00000412468 NM_001102614.1 5 caC/caT 0 +SLC38A3 UCSF GRCh37 3 50255394 50255394 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 57 91 0 ENST00000420502.1:n.1054C>T *352* ENST00000420502 0 +SLC38A8 UCSF GRCh37 16 84050245 84050245 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 44 33 0 ENST00000299709.3:c.1041G>A p.Arg347= p.R347= ENST00000299709 NM_001080442.1 347 cgG/cgA 0 +SLC39A2 UCSF GRCh37 14 21467698 21467698 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 101 37 118 0 ENST00000298681.4:c.93G>A p.Trp31Ter p.W31* ENST00000298681 NM_014579.3 31 tgG/tgA 0 +SLC41A2 UCSF GRCh37 12 105260296 105260296 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 33 60 0 ENST00000258538.3:c.1089G>A p.Trp363Ter p.W363* ENST00000258538 NM_032148.3 363 tgG/tgA 0 +SLC4A10 UCSF GRCh37 2 162807267 162807267 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 40 40 0 ENST00000446997.1:c.2450C>T p.Ala817Val p.A817V ENST00000446997 NM_001178015.1 817 gCt/gTt 0 +SLC4A2 UCSF GRCh37 7 150762019 150762019 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 33 32 0 ENST00000485713.1:c.544G>A p.Ala182Thr p.A182T ENST00000485713 NM_001199692.1 182 Gcg/Acg 0 +SLC4A2 UCSF GRCh37 7 150768682 150768682 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 21 21 0 ENST00000485713.1:c.2181G>A p.Gly727= p.G727= ENST00000485713 NM_001199692.1 727 ggG/ggA 0 +SLC4A3 UCSF GRCh37 2 220500543 220500543 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 9 12 9 0 ENST00000373762.3:c.2202G>A p.Gln734= p.Q734= ENST00000373762 NM_005070.3 734 caG/caA 0 +SLC4A7 UCSF GRCh37 3 27424686 27424686 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 30 53 0 ENST00000295736.5:c.3521G>A p.Gly1174Glu p.G1174E ENST00000295736 NM_003615.4 1174 gGg/gAg 0 +SLC4A7 UCSF GRCh37 3 27453176 27453176 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 19 28 0 ENST00000295736.5:c.1696G>A p.Glu566Lys p.E566K ENST00000295736 NM_003615.4 566 Gag/Aag 0 +SLC5A3 UCSF GRCh37 21 35468772 35468772 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 44 64 0 ENST00000381151.3:c.1275G>A p.Trp425Ter p.W425* ENST00000381151 425 tgG/tgA 0 +SLC5A5 UCSF GRCh37 19 17986865 17986865 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 28 42 0 ENST00000222248.3:c.648C>T p.Pro216= p.P216= ENST00000222248 NM_000453.2 216 ccC/ccT 0 +SLC5A6 UCSF GRCh37 2 27426165 27426165 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 31 62 0 ENST00000310574.3:c.1143C>T p.Asp381= p.D381= ENST00000310574 NM_021095.2 381 gaC/gaT 0 +SLC5A9 UCSF GRCh37 1 48703449 48703449 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 43 22 45 0 ENST00000236495.5:c.1466C>T p.Thr489Ile p.T489I ENST00000236495 NM_001135181.1 489 aCc/aTc 0 +SLC6A14 UCSF GRCh37 X 115577980 115577980 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 93 54 39 0 ENST00000371900.4:c.863G>A p.Gly288Asp p.G288D ENST00000371900 NM_007231.3 288 gGt/gAt 0 +SLC6A16 UCSF GRCh37 19 49812602 49812602 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 13 51 0 ENST00000335875.4:c.943C>T p.Leu315= p.L315= ENST00000335875 NM_014037.2 315 Ctg/Ttg 0 +SLC6A18 UCSF GRCh37 5 1225747 1225747 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 33 40 0 ENST00000324642.3:c.155G>A p.Gly52Glu p.G52E ENST00000324642 NM_182632.2 52 gGa/gAa 0 +SLC6A20 UCSF GRCh37 3 45817423 45817423 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 76 53 62 0 ENST00000358525.4:c.412G>A p.Glu138Lys p.E138K ENST00000358525 NM_020208.3 138 Gag/Aag 0 +SLC7A6 UCSF GRCh37 16 68325475 68325475 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 136 56 89 0 ENST00000566454.1:c.933G>A p.Gln311= p.Q311= ENST00000566454 NM_001076785.2 311 caG/caA 0 +SLC8A2 UCSF GRCh37 19 47935511 47935511 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 77 49 54 0 ENST00000236877.6:c.2302G>A p.Asp768Asn p.D768N ENST00000236877 NM_015063.2 768 Gac/Aac 0 +SLC9A3 UCSF GRCh37 5 476142 476142 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 11 8 0 ENST00000264938.3:c.2133G>A p.Lys711= p.K711= ENST00000264938 NM_004174.2 711 aaG/aaA 0 +SLC9A5 UCSF GRCh37 16 67289019 67289019 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 98 46 56 0 ENST00000299798.11:c.586G>A p.Val196Met p.V196M ENST00000299798 NM_004594.2 196 Gtg/Atg 0 +SLC9A8 UCSF GRCh37 20 48503313 48503313 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 51 25 0 ENST00000417961.1:c.1564C>T p.Leu522= p.L522= ENST00000417961 NM_015266.2 522 Ctg/Ttg 0 +SLFN12L UCSF GRCh37 17 33802212 33802212 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 214 122 259 0 ENST00000260908.7:c.1497G>A p.Lys499= p.K499= ENST00000260908 NM_001195790.1 499 aaG/aaA 0 +SMAD4 UCSF GRCh37 18 48573634 48573634 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 101 57 88 0 ENST00000342988.3:c.218C>T p.Thr73Ile p.T73I ENST00000342988 NM_005359.5 73 aCc/aTc 0 +SMAD6 UCSF GRCh37 15 67073393 67073393 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 11 10 0 ENST00000288840.5:c.1011G>A p.Trp337Ter p.W337* ENST00000288840 NM_005585.4 337 tgG/tgA 0 +SMAD7 UCSF GRCh37 18 46448254 46448254 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 45 25 64 0 ENST00000262158.2:c.769G>A p.Asp257Asn p.D257N ENST00000262158 NM_001190821.1 257 Gat/Aat 0 +SMAP2 UCSF GRCh37 1 40872408 40872408 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 47 88 0 ENST00000372718.3:c.104G>A p.Gly35Glu p.G35E ENST00000372718 NM_022733.2 35 gGg/gAg 0 +SMARCA4 UCSF GRCh37 19 11144135 11144135 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 120 85 31 0 ENST00000344626.4:c.3716C>T p.Ser1239Phe p.S1239F ENST00000344626 NM_003072.3 1239 tCc/tTc 0 +SMARCB1 UCSF GRCh37 22 24167504 24167504 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 38 58 0 ENST00000263121.7:c.888G>A p.Lys296= p.K296= ENST00000263121 NM_003073.3 296 aaG/aaA 0 +SMCR8 UCSF GRCh37 17 18220997 18220997 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 56 77 0 ENST00000406438.3:c.1894G>A p.Val632Met p.V632M ENST00000406438 NM_144775.2 632 Gtg/Atg 0 +SMG6 UCSF GRCh37 17 1972222 1972222 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 15 21 0 ENST00000263073.6:c.3685G>A p.Val1229Ile p.V1229I ENST00000263073 NM_017575.4 1229 Gtc/Atc 0 +SNAPC4 UCSF GRCh37 9 139292825 139292825 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 235 73 92 0 ENST00000298532.2:c.56G>A p.Arg19Lys p.R19K ENST00000298532 NM_003086.2 19 aGg/aAg 0 +SNAPC4 UCSF GRCh37 9 139282275 139282275 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 94 34 42 0 ENST00000298532.2:c.1149C>T p.Asp383= p.D383= ENST00000298532 NM_003086.2 383 gaC/gaT 0 +SNRNP200 UCSF GRCh37 2 96953181 96953181 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 93 53 84 0 ENST00000323853.5:c.3480G>A p.Glu1160= p.E1160= ENST00000323853 NM_014014.4 1160 gaG/gaA 0 +SNX13 UCSF GRCh37 7 17930075 17930075 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 86 64 72 0 ENST00000428135.3:c.351G>A p.Gln117= p.Q117= ENST00000428135 NM_015132.4 117 caG/caA 0 +SOCS2 UCSF GRCh37 12 93968767 93968767 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 38 93 0 ENST00000340600.2:c.409C>T p.Arg137Trp p.R137W ENST00000340600 NM_003877.4 137 Cgg/Tgg 0 +SORT1 UCSF GRCh37 1 109857328 109857328 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 29 20 0 ENST00000256637.6:c.2323G>A p.Val775Met p.V775M ENST00000256637 NM_002959.5 775 Gtg/Atg 0 +SOX11 UCSF GRCh37 2 5833235 5833235 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 13 21 8 0 ENST00000322002.3:c.382C>T p.Pro128Ser p.P128S ENST00000322002 NM_003108.3 128 Ccc/Tcc 0 +SP110 UCSF GRCh37 2 231042370 231042370 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 84 191 0 ENST00000258381.6:c.1474G>A p.Glu492Lys p.E492K ENST00000258381 NM_080424.2 492 Gag/Aag 0 +SPAG1 UCSF GRCh37 8 101251583 101251583 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 64 103 0 ENST00000388798.2:c.2231C>T p.Thr744Ile p.T744I ENST00000388798 NM_003114.4 744 aCa/aTa 0 +SPDYE3 UCSF GRCh37 7 99917195 99917195 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 288 130 256 0 ENST00000332397.6:c.1354G>A p.Ala452Thr p.A452T ENST00000332397 NM_001004351.4 452 Gcc/Acc 0 +SPHKAP UCSF GRCh37 2 228883799 228883799 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 34 45 0 ENST00000392056.3:c.1771C>T p.Pro591Ser p.P591S ENST00000392056 NM_001142644.1 591 Cct/Tct 0 +SPIN1 UCSF GRCh37 9 91083400 91083400 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 62 87 0 ENST00000375859.3:c.469G>A p.Ala157Thr p.A157T ENST00000375859 NM_006717.2 157 Gca/Aca 0 +SPINT1 UCSF GRCh37 15 41136919 41136919 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 12 9 0 ENST00000344051.4:c.167C>T p.Ala56Val p.A56V ENST00000344051 56 gCc/gTc 0 +SPOP UCSF GRCh37 17 47700133 47700133 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 71 39 87 0 ENST00000347630.2:c.40T>G p.Ser14Ala p.S14A ENST00000347630 NM_001007230.1 14 Tcg/Gcg 0 +SPR UCSF GRCh37 2 73118536 73118536 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 15 40 0 ENST00000234454.5:c.656G>A p.Arg219Gln p.R219Q ENST00000234454 NM_003124.4 219 cGa/cAa 0 +SPRR2D UCSF GRCh37 1 153012683 153012683 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 82 61 121 0 ENST00000368757.1:c.140C>T p.Pro47Leu p.P47L ENST00000368757 47 cCt/cTt 0 +SPTA1 UCSF GRCh37 1 158644362 158644362 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 158 103 91 0 ENST00000368147.4:c.1216G>A p.Glu406Lys p.E406K ENST00000368147 NM_003126.2 406 Gaa/Aaa 0 +SRCAP UCSF GRCh37 16 30735216 30735216 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 84 54 84 0 ENST00000262518.4:c.4471C>T p.Pro1491Ser p.P1491S ENST00000262518 NM_006662.2 1491 Ccc/Tcc 0 +SRD5A3 UCSF GRCh37 4 56230317 56230317 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 121 71 113 0 ENST00000264228.4:c.441C>T p.Cys147= p.C147= ENST00000264228 NM_024592.4 147 tgC/tgT 0 +SREBF2 UCSF GRCh37 22 42298982 42298982 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 8 9 8 0 ENST00000361204.4:c.2916G>A p.Gln972= p.Q972= ENST00000361204 NM_004599.3 972 caG/caA 0 +SRGAP1 UCSF GRCh37 12 64536317 64536317 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 89 52 124 0 ENST00000355086.3:c.3123G>A p.Met1041Ile p.M1041I ENST00000355086 NM_020762.2 1041 atG/atA 0 +SRGAP3 UCSF GRCh37 3 9057317 9057317 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 115 21 60 0 ENST00000383836.3:c.1777C>T p.Pro593Ser p.P593S ENST00000383836 NM_014850.3 593 Cct/Tct 0 +SRL UCSF GRCh37 16 4247874 4247874 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 50 11 43 0 ENST00000399609.3:c.302C>T p.Pro101Leu p.P101L ENST00000399609 NM_001098814.1 101 cCg/cTg 0 +SRM UCSF GRCh37 1 11118930 11118930 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 14 6 8 0 ENST00000376957.2:c.308G>A p.Gly103Glu p.G103E ENST00000376957 NM_003132.2 103 gGa/gAa 0 +SRRD UCSF GRCh37 22 26882013 26882013 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 40 49 0 ENST00000215917.7:c.234C>T p.Phe78= p.F78= ENST00000215917 NM_001013694.2 78 ttC/ttT 0 +SRRM2 UCSF GRCh37 16 2811898 2811898 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 203 114 126 0 ENST00000301740.8:c.1369C>T p.Pro457Ser p.P457S ENST00000301740 NM_016333.3 457 Ccc/Tcc 0 +SRRM2 UCSF GRCh37 16 2809654 2809654 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 29 72 0 ENST00000301740.8:c.825C>T p.Ser275= p.S275= ENST00000301740 NM_016333.3 275 tcC/tcT 0 +SRSF12 UCSF GRCh37 6 89808575 89808575 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 193 135 247 0 ENST00000452027.2:c.508C>T p.Pro170Ser p.P170S ENST00000452027 NM_080743.4 170 Cca/Tca 0 +SRSF9 UCSF GRCh37 12 120899861 120899861 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 83 42 34 0 ENST00000229390.3:c.627G>A p.Arg209= p.R209= ENST00000229390 NM_003769.2 209 agG/agA 0 +SS18L1 UCSF GRCh37 20 60737983 60737983 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 15 15 0 ENST00000331758.3:c.552C>T p.Asn184= p.N184= ENST00000331758 NM_198935.1 184 aaC/aaT 0 +SSC5D UCSF GRCh37 19 56029025 56029025 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 47 74 130 0 ENST00000389623.6:c.3382G>A p.Asp1128Asn p.D1128N ENST00000389623 NM_001144950.1 1128 Gac/Aac 0 +SSPO UCSF GRCh37 7 149528267 149528267 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 16 7 15 0 ENST00000378016.2:n.15186C>T *5062* ENST00000378016 0 +ST6GAL2 UCSF GRCh37 2 107423348 107423348 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 17 33 0 ENST00000409382.3:c.1376C>T p.Ser459Phe p.S459F ENST00000409382 NM_001142351.1 459 tCc/tTc 0 +ST6GALNAC1 UCSF GRCh37 17 74621610 74621610 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 13 31 0 ENST00000156626.7:c.1606-1G>A p.X536_splice ENST00000156626 NM_018414.3 0 +ST6GALNAC5 UCSF GRCh37 1 77510220 77510220 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 242 124 100 0 ENST00000477717.1:c.593G>A p.Arg198Gln p.R198Q ENST00000477717 NM_030965.1 198 cGg/cAg 0 +STAC3 UCSF GRCh37 12 57643386 57643386 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 27 27 0 ENST00000332782.2:c.34C>T p.Pro12Ser p.P12S ENST00000332782 NM_145064.1 12 Ccc/Tcc 0 +STAG3 UCSF GRCh37 7 99798542 99798542 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 27 50 0 ENST00000426455.1:c.2011G>A p.Val671Ile p.V671I ENST00000426455 NM_001282716.1 671 Gta/Ata 0 +STEAP3 UCSF GRCh37 2 120003184 120003184 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 27 41 0 ENST00000393110.2:c.142G>A p.Asp48Asn p.D48N ENST00000393110 48 Gac/Aac 0 +STK17A UCSF GRCh37 7 43647960 43647960 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 106 40 76 0 ENST00000319357.5:c.525C>T p.His175= p.H175= ENST00000319357 NM_004760.2 175 caC/caT 0 +STK17B UCSF GRCh37 2 197002250 197002250 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 44 87 0 ENST00000263955.4:c.1040G>A p.Ser347Asn p.S347N ENST00000263955 NM_004226.3 347 aGc/aAc 0 +STK36 UCSF GRCh37 2 219563972 219563972 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 44 53 0 ENST00000295709.3:c.3705G>A p.Gln1235= p.Q1235= ENST00000295709 NM_015690.4 1235 caG/caA 0 +STON2 UCSF GRCh37 14 81743681 81743681 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 59 61 0 ENST00000555447.1:c.1974C>T p.Asn658= p.N658= ENST00000555447 NM_001256430.1 658 aaC/aaT 0 +STRAP UCSF GRCh37 12 16048406 16048406 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 68 26 57 0 ENST00000419869.2:c.614C>G p.Ser205Cys p.S205C ENST00000419869 NM_007178.3 205 tCt/tGt 0 +STXBP3 UCSF GRCh37 1 109319021 109319021 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 19 23 0 ENST00000370008.3:c.660G>A p.Lys220= p.K220= ENST00000370008 NM_007269.2 220 aaG/aaA 0 +SUPT5H UCSF GRCh37 19 39960873 39960873 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 81 91 0 ENST00000599117.1:c.1489G>A p.Glu497Lys p.E497K ENST00000599117 497 Gag/Aag 0 +SVEP1 UCSF GRCh37 9 113244691 113244691 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 79 49 70 0 ENST00000401783.2:c.2120C>T p.Thr707Ile p.T707I ENST00000401783 NM_153366.3 707 aCt/aTt 0 +SYMPK UCSF GRCh37 19 46357650 46357650 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 33 33 0 ENST00000245934.7:c.104G>A p.Arg35Lys p.R35K ENST00000245934 NM_004819.2 35 aGg/aAg 0 +SYNE1 UCSF GRCh37 6 152640094 152640094 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 30 49 0 ENST00000367255.5:c.16293C>T p.Ser5431= p.S5431= ENST00000367255 NM_182961.3 5431 agC/agT 0 +SYNE2 UCSF GRCh37 14 64518895 64518895 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 112 41 150 0 ENST00000358025.3:c.8264C>T p.Pro2755Leu p.P2755L ENST00000358025 NM_182914.2 2755 cCc/cTc 0 +SYNE2 UCSF GRCh37 14 64554542 64554542 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 37 72 0 ENST00000358025.3:c.11638G>A p.Glu3880Lys p.E3880K ENST00000358025 NM_182914.2 3880 Gaa/Aaa 0 +SYNE2 UCSF GRCh37 14 64608671 64608671 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 13 44 0 ENST00000358025.3:c.15171G>A p.Glu5057= p.E5057= ENST00000358025 NM_182914.2 5057 gaG/gaA 0 +SYNGR1 UCSF GRCh37 22 39770548 39770548 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 36 40 0 ENST00000328933.5:c.327C>T p.Ile109= p.I109= ENST00000328933 NM_004711.4 109 atC/atT 0 +SYNRG UCSF GRCh37 17 35930949 35930949 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 50 131 0 ENST00000339208.6:c.1134C>T p.Asn378= p.N378= ENST00000339208 NM_001163544.1 378 aaC/aaT 0 +SYTL4 UCSF GRCh37 X 99956471 99956471 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 25 42 96 0 ENST00000455616.1:c.309G>A p.Lys103= p.K103= ENST00000455616 103 aaG/aaA 0 +TAAR6 UCSF GRCh37 6 132891711 132891711 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 116 65 127 0 ENST00000275198.1:c.251C>T p.Thr84Ile p.T84I ENST00000275198 NM_175067.1 84 aCt/aTt 0 +TAAR9 UCSF GRCh37 6 132860441 132860441 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 17 13 0 ENST00000434551.1:c.1013C>T p.Thr338Ile p.T338I ENST00000434551 NM_175057.3 338 aCt/aTt 0 +TACR3 UCSF GRCh37 4 104510962 104510962 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 104 80 137 0 ENST00000304883.2:c.1275G>A p.Arg425= p.R425= ENST00000304883 NM_001059.2 425 cgG/cgA 0 +TADA1 UCSF GRCh37 1 166831645 166831645 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 32 61 0 ENST00000367874.4:c.335G>A p.Arg112Lys p.R112K ENST00000367874 NM_053053.3 112 aGa/aAa 0 +TAF3 UCSF GRCh37 10 8056708 8056708 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 107 50 65 0 ENST00000344293.5:c.2784C>T p.Ala928= p.A928= ENST00000344293 NM_031923.3 928 gcC/gcT 0 +TAF5L UCSF GRCh37 1 229730455 229730455 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 143 83 66 0 ENST00000258281.2:c.1359G>A p.Trp453Ter p.W453* ENST00000258281 NM_014409.3 453 tgG/tgA 0 +TANC1 UCSF GRCh37 2 160035165 160035165 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 38 62 0 ENST00000263635.6:c.2001G>A p.Arg667= p.R667= ENST00000263635 NM_033394.2 667 agG/agA 0 +TANC2 UCSF GRCh37 17 61489467 61489467 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 46 73 0 ENST00000424789.2:c.3652C>T p.Leu1218Phe p.L1218F ENST00000424789 NM_025185.3 1218 Ctt/Ttt 0 +TAOK3 UCSF GRCh37 12 118619193 118619193 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 45 65 1 ENST00000392533.3:c.1549G>A p.Ala517Thr p.A517T ENST00000392533 NM_016281.3 517 Gct/Act 0 +TAPT1 UCSF GRCh37 4 16177816 16177816 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 56 69 0 ENST00000405303.2:c.1033G>A p.Val345Ile p.V345I ENST00000405303 NM_153365.2 345 Gta/Ata 0 +TARBP1 UCSF GRCh37 1 234556505 234556505 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 35 62 0 ENST00000040877.1:c.3498C>T p.His1166= p.H1166= ENST00000040877 NM_005646.3 1166 caC/caT 0 +TAS2R5 UCSF GRCh37 7 141490830 141490830 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 60 92 0 ENST00000247883.4:c.669C>T p.Ser223= p.S223= ENST00000247883 NM_018980.2 223 tcC/tcT 0 +TBC1D13 UCSF GRCh37 9 131568554 131568554 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 30 34 0 ENST00000372648.5:c.1101G>A p.Leu367= p.L367= ENST00000372648 NM_018201.3 367 ctG/ctA 0 +TBC1D14 UCSF GRCh37 4 6925123 6925123 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 126 75 91 0 ENST00000409757.4:c.7G>A p.Asp3Asn p.D3N ENST00000409757 NM_020773.2 3 Gat/Aat 0 +TBC1D15 UCSF GRCh37 12 72291654 72291654 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 43 76 0 ENST00000550746.1:c.1167G>A p.Gln389= p.Q389= ENST00000550746 NM_022771.4 389 caG/caA 0 +TBC1D17 UCSF GRCh37 19 50385388 50385388 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 188 96 101 0 ENST00000221543.5:c.618G>A p.Gln206= p.Q206= ENST00000221543 NM_024682.2 206 caG/caA 0 +TBC1D22B UCSF GRCh37 6 37250008 37250008 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 61 33 60 0 ENST00000373491.3:c.469C>T p.Leu157Phe p.L157F ENST00000373491 NM_017772.2 157 Ctc/Ttc 0 +TBC1D24 UCSF GRCh37 16 2546449 2546449 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 37 20 0 ENST00000293970.5:c.300G>A p.Gln100= p.Q100= ENST00000293970 NM_001199107.1 100 caG/caA 0 +TBK1 UCSF GRCh37 12 64879234 64879234 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 12 12 21 0 ENST00000331710.5:c.1190-1G>A p.X397_splice ENST00000331710 NM_013254.3 0 +TBL1X UCSF GRCh37 X 9652205 9652205 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 26 59 0 ENST00000217964.7:c.334G>A p.Glu112Lys p.E112K ENST00000217964 NM_005647.3 112 Gag/Aag 0 +TBL1XR1 UCSF GRCh37 3 176752054 176752054 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 50 45 59 0 ENST00000430069.1:c.1182T>G p.Ile394Met p.I394M ENST00000430069 394 atT/atG 0 +TBX6 UCSF GRCh37 16 30097950 30097950 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 10 16 0 ENST00000395224.2:c.980C>T p.Ala327Val p.A327V ENST00000395224 NM_004608.3 327 gCc/gTc 0 +TCF4 UCSF GRCh37 18 52924585 52924585 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 44 77 0 ENST00000398339.1:c.1413C>T p.Ala471= p.A471= ENST00000398339 NM_001243226.1 471 gcC/gcT 0 +TCHH UCSF GRCh37 1 152080381 152080381 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 118 60 87 0 ENST00000368804.1:c.5312G>A p.Arg1771Lys p.R1771K ENST00000368804 NM_007113.3 1771 aGa/aAa 0 +TCHH UCSF GRCh37 1 152083503 152083503 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 195 128 83 0 ENST00000368804.1:c.2190G>A p.Arg730= p.R730= ENST00000368804 NM_007113.3 730 agG/agA 0 +TCP1 UCSF GRCh37 6 160200142 160200142 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 46 88 0 ENST00000321394.7:c.1606G>A p.Glu536Lys p.E536K ENST00000321394 NM_030752.2 536 Gaa/Aaa 0 +TCP11 UCSF GRCh37 6 35090045 35090045 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 40 91 0 ENST00000311875.5:c.466G>A p.Asp156Asn p.D156N ENST00000311875 156 Gac/Aac 0 +TCP11L2 UCSF GRCh37 12 106715328 106715328 + missense_variant Missense_Mutation SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 63 25 58 0 ENST00000299045.3:c.479A>C p.Asp160Ala p.D160A ENST00000299045 NM_152772.1 160 gAc/gCc 0 +TDRD10 UCSF GRCh37 1 154515281 154515281 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 19 26 0 ENST00000368480.3:c.487G>A p.Val163Ile p.V163I ENST00000368480 163 Gtc/Atc 0 +TDRD9 UCSF GRCh37 14 104441851 104441851 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 75 62 120 0 ENST00000409874.4:c.972G>A p.Glu324= p.E324= ENST00000409874 NM_153046.2 324 gaG/gaA 0 +TEAD4 UCSF GRCh37 12 3129818 3129818 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 57 20 19 0 ENST00000359864.2:c.602G>A p.Gly201Glu p.G201E ENST00000359864 NM_003213.3 201 gGg/gAg 0 +TECPR1 UCSF GRCh37 7 97867907 97867907 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 39 79 0 ENST00000447648.2:c.949G>A p.Gly317Ser p.G317S ENST00000447648 NM_015395.2 317 Ggc/Agc 0 +TENC1 UCSF GRCh37 12 53453496 53453496 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 57 34 16 0 ENST00000314276.3:c.2101C>T p.Pro701Ser p.P701S ENST00000314276 NM_015319.2 701 Cca/Tca 0 +TEP1 UCSF GRCh37 14 20852280 20852280 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 23 35 0 ENST00000262715.5:c.3451G>A p.Asp1151Asn p.D1151N ENST00000262715 NM_007110.4 1151 Gac/Aac 0 +TERF2 UCSF GRCh37 16 69419376 69419376 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 141 57 56 0 ENST00000603068.1:c.267G>A p.Arg89= p.R89= ENST00000603068 89 agG/agA 0 +TET2 UCSF GRCh37 4 106158049 106158049 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 69 43 94 0 ENST00000380013.4:c.2950G>A p.Glu984Lys p.E984K ENST00000380013 NM_001127208.2 984 Gaa/Aaa 0 +TEX11 UCSF GRCh37 X 69830352 69830352 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 62 99 0 ENST00000395889.2:c.1837+1G>A p.X613_splice ENST00000395889 NM_001003811.1 0 +TEX15 UCSF GRCh37 8 30706062 30706062 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 24 96 0 ENST00000256246.2:c.472C>T p.Pro158Ser p.P158S ENST00000256246 NM_031271.3 158 Cca/Tca 0 +TFAP2E UCSF GRCh37 1 36056336 36056336 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 8 13 0 ENST00000373235.3:c.1006G>A p.Gly336Arg p.G336R ENST00000373235 NM_178548.3 336 Ggg/Agg 0 +TFB2M UCSF GRCh37 1 246711846 246711846 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 24 44 0 ENST00000366514.4:c.858+1G>A p.X286_splice ENST00000366514 NM_022366.2 0 +TGM2 UCSF GRCh37 20 36770591 36770591 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 26 52 0 ENST00000361475.2:c.870C>T p.Cys290= p.C290= ENST00000361475 NM_004613.2 290 tgC/tgT 0 +TGM7 UCSF GRCh37 15 43571977 43571977 + synonymous_variant Silent SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 169 24 57 1 ENST00000452443.2:c.1524G>T p.Leu508= p.L508= ENST00000452443 NM_052955.2 508 ctG/ctT 0 +TH1L UCSF GRCh37 20 57568578 57568578 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 27 60 0 ENST00000602795.1:c.1473C>T p.Ser491= p.S491= ENST00000602795 NM_198976.2 491 tcC/tcT 0 +THBS1 UCSF GRCh37 15 39880853 39880853 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 22 29 0 ENST00000260356.5:c.1598G>A p.Gly533Asp p.G533D ENST00000260356 NM_003246.2 533 gGt/gAt 0 +THNSL1 UCSF GRCh37 10 25313108 25313108 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 67 34 47 0 ENST00000524413.1:c.956G>A p.Gly319Glu p.G319E ENST00000524413 319 gGg/gAg 0 +THRAP3 UCSF GRCh37 1 36757032 36757032 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 35 37 60 0 ENST00000354618.5:c.1803C>T p.Asn601= p.N601= ENST00000354618 NM_005119.3 601 aaC/aaT 0 +THRSP UCSF GRCh37 11 77775109 77775109 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 59 39 55 0 ENST00000281030.2:c.182C>T p.Thr61Ile p.T61I ENST00000281030 NM_003251.3 61 aCc/aTc 0 +THSD1 UCSF GRCh37 13 52952735 52952735 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 47 42 0 ENST00000258613.4:c.1370C>T p.Pro457Leu p.P457L ENST00000258613 NM_018676.3 457 cCc/cTc 0 +THSD1 UCSF GRCh37 13 52952267 52952267 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 62 27 70 0 ENST00000258613.4:c.1838A>C p.Gln613Pro p.Q613P ENST00000258613 NM_018676.3 613 cAg/cCg 0 +TIMELESS UCSF GRCh37 12 56818588 56818588 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 48 25 49 0 ENST00000553532.1:c.1826C>T p.Ala609Val p.A609V ENST00000553532 609 gCt/gTt 0 +TIMELESS UCSF GRCh37 12 56815272 56815272 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 100 37 91 0 ENST00000553532.1:c.2731C>T p.Leu911= p.L911= ENST00000553532 911 Ctg/Ttg 0 +TJP2 UCSF GRCh37 9 71827508 71827508 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 44 18 66 0 ENST00000539225.1:c.198C>T p.Thr66= p.T66= ENST00000539225 NM_001170416.1 66 acC/acT 0 +TLK1 UCSF GRCh37 2 171917607 171917607 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 30 32 0 ENST00000431350.2:c.390G>A p.Gln130= p.Q130= ENST00000431350 130 caG/caA 0 +TLL2 UCSF GRCh37 10 98133449 98133449 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 36 50 0 ENST00000357947.3:c.2566C>T p.Pro856Ser p.P856S ENST00000357947 NM_012465.3 856 Cca/Tca 0 +TLR9 UCSF GRCh37 3 52257979 52257979 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 50 57 0 ENST00000360658.2:c.353C>T p.Thr118Ile p.T118I ENST00000360658 NM_017442.3 118 aCc/aTc 0 +TM7SF2 UCSF GRCh37 11 64880745 64880745 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 76 32 14 0 ENST00000279263.7:c.358G>A p.Gly120Arg p.G120R ENST00000279263 NM_003273.3 120 Ggg/Agg 0 +TMC3 UCSF GRCh37 15 81627077 81627077 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 35 67 0 ENST00000359440.5:c.2443G>A p.Glu815Lys p.E815K ENST00000359440 NM_001080532.1 815 Gag/Aag 0 +TMCO7 UCSF GRCh37 16 69056828 69056828 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 33 55 0 ENST00000261778.1:c.2940C>T p.Asn980= p.N980= ENST00000261778 NM_024562.1 980 aaC/aaT 0 +TMED10 UCSF GRCh37 14 75614367 75614367 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 32 54 0 ENST00000303575.4:c.411G>A p.Glu137= p.E137= ENST00000303575 NM_006827.5 137 gaG/gaA 0 +TMEM102 UCSF GRCh37 17 7340310 7340310 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 27 20 8 0 ENST00000323206.1:c.1012G>A p.Gly338Ser p.G338S ENST00000323206 NM_178518.2 338 Ggt/Agt 0 +TMEM130 UCSF GRCh37 7 98457806 98457806 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 29 12 24 0 ENST00000416379.2:c.547G>A p.Asp183Asn p.D183N ENST00000416379 183 Gac/Aac 0 +TMEM132D UCSF GRCh37 12 129559485 129559485 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 87 43 57 0 ENST00000422113.2:c.2235C>T p.Ile745= p.I745= ENST00000422113 NM_133448.2 745 atC/atT 0 +TMEM154 UCSF GRCh37 4 153573939 153573939 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 36 75 0 ENST00000304385.3:c.205C>T p.Pro69Ser p.P69S ENST00000304385 NM_152680.2 69 Ccg/Tcg 0 +TMEM168 UCSF GRCh37 7 112424274 112424274 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 109 35 76 0 ENST00000312814.6:c.607C>T p.Pro203Ser p.P203S ENST00000312814 NM_001287497.1 203 Cca/Tca 0 +TMEM47 UCSF GRCh37 X 34657367 34657367 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 5 10 26 0 ENST00000275954.3:c.364G>A p.Ala122Thr p.A122T ENST00000275954 NM_031442.3 122 Gca/Aca 0 +TMEM48 UCSF GRCh37 1 54262697 54262697 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 66 36 66 0 ENST00000371429.3:c.1343G>A p.Gly448Glu p.G448E ENST00000371429 NM_001168551.1 448 gGg/gAg 0 +TMEM5 UCSF GRCh37 12 64202714 64202714 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 24 79 0 ENST00000261234.6:c.1174C>T p.Leu392Phe p.L392F ENST00000261234 NM_014254.2 392 Ctc/Ttc 0 +TMEM63A UCSF GRCh37 1 226062017 226062017 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 35 37 0 ENST00000366835.3:c.237C>T p.Gly79= p.G79= ENST00000366835 NM_014698.2 79 ggC/ggT 0 +TMEM63C UCSF GRCh37 14 77706066 77706066 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 23 10 10 0 ENST00000298351.4:c.927G>A p.Lys309= p.K309= ENST00000298351 NM_020431.2 309 aaG/aaA 0 +TMEM66 UCSF GRCh37 8 29927334 29927334 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 74 35 97 0 ENST00000256255.6:c.524G>A p.Gly175Glu p.G175E ENST00000256255 NM_016127.4 175 gGa/gAa 0 +TMEM67 UCSF GRCh37 8 94793962 94793962 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 22 26 0 ENST00000453321.3:c.1055G>A p.Gly352Asp p.G352D ENST00000453321 NM_153704.5 352 gGt/gAt 0 +TMEM8A UCSF GRCh37 16 422611 422611 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 102 70 46 0 ENST00000431232.2:c.2019G>A p.Trp673Ter p.W673* ENST00000431232 NM_021259.2 673 tgG/tgA 0 +TMIGD1 UCSF GRCh37 17 28652071 28652071 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 94 57 89 0 ENST00000328886.4:c.403G>A p.Glu135Lys p.E135K ENST00000328886 NM_206832.1 135 Gaa/Aaa 0 +TMIGD2 UCSF GRCh37 19 4297985 4297985 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 89 79 0 ENST00000301272.2:c.404C>T p.Pro135Leu p.P135L ENST00000301272 NM_144615.2 135 cCa/cTa 0 +TMOD4 UCSF GRCh37 1 151146957 151146957 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 147 76 106 0 ENST00000295314.4:c.190G>A p.Asp64Asn p.D64N ENST00000295314 NM_013353.2 64 Gac/Aac 0 +TMPRSS11D UCSF GRCh37 4 68703921 68703921 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 59 33 55 0 ENST00000283916.6:c.444C>T p.Asn148= p.N148= ENST00000283916 NM_004262.2 148 aaC/aaT 0 +TMPRSS15 UCSF GRCh37 21 19744516 19744516 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 45 23 51 0 ENST00000284885.3:c.658A>C p.Met220Leu p.M220L ENST00000284885 NM_002772.2 220 Atg/Ctg 0 +TMPRSS7 UCSF GRCh37 3 111797718 111797718 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 33 37 59 0 ENST00000419127.1:c.1976C>T p.Ala659Val p.A659V ENST00000419127 NM_001042575.2 659 gCc/gTc 0 +TMX3 UCSF GRCh37 18 66364480 66364480 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 21 6 9 0 ENST00000299608.2:c.553G>A p.Glu185Lys p.E185K ENST00000299608 NM_019022.3 185 Gaa/Aaa 0 +TNK1 UCSF GRCh37 17 7292202 7292202 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 19 13 15 0 ENST00000576812.1:c.1887G>A p.Lys629= p.K629= ENST00000576812 NM_001251902.1 629 aaG/aaA 0 +TNKS1BP1 UCSF GRCh37 11 57077016 57077016 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 88 77 60 0 ENST00000532437.1:c.3169G>A p.Val1057Met p.V1057M ENST00000532437 1057 Gtg/Atg 0 +TNPO2 UCSF GRCh37 19 12826505 12826505 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 31 41 0 ENST00000425528.1:c.374C>T p.Pro125Leu p.P125L ENST00000425528 125 cCc/cTc 0 +TNPO2 UCSF GRCh37 19 12814595 12814595 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 38 11 26 0 ENST00000425528.1:c.2043G>A p.Arg681= p.R681= ENST00000425528 681 cgG/cgA 0 +TNRC6A UCSF GRCh37 16 24801750 24801750 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 58 88 0 ENST00000395799.3:c.1787G>A p.Gly596Glu p.G596E ENST00000395799 NM_014494.2 596 gGa/gAa 0 +TNS3 UCSF GRCh37 7 47408592 47408592 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 111 40 35 1 ENST00000398879.1:c.1651C>T p.Arg551Trp p.R551W ENST00000398879 551 Cgg/Tgg 0 +TOMM7 UCSF GRCh37 7 22862346 22862346 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 197 64 75 0 ENST00000358435.4:c.53G>A p.Gly18Glu p.G18E ENST00000358435 NM_019059.3 18 gGg/gAg 0 +TONSL UCSF GRCh37 8 145661746 145661746 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 32 27 0 ENST00000409379.3:c.2070G>A p.Glu690= p.E690= ENST00000409379 NM_013432.4 690 gaG/gaA 0 +TOP1 UCSF GRCh37 20 39729897 39729897 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 46 77 0 ENST00000361337.2:c.1212C>T p.Val404= p.V404= ENST00000361337 NM_003286.2 404 gtC/gtT 0 +TOP1MT UCSF GRCh37 8 144403488 144403488 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 28 16 0 ENST00000329245.4:c.1029C>T p.Leu343= p.L343= ENST00000329245 NM_052963.2 343 ctC/ctT 0 +TOP2B UCSF GRCh37 3 25650771 25650771 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 92 16 35 0 ENST00000435706.2:c.3981G>A p.Arg1327= p.R1327= ENST00000435706 NM_001068.3 1327 cgG/cgA 0 +TP53 UCSF GRCh37 17 7578211 7578211 + missense_variant Missense_Mutation SNP C C G NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 41 23 46 0 ENST00000269305.4:c.638G>C p.Arg213Pro p.R213P ENST00000269305 NM_001126112.2 213 cGa/cCa 0 +TP53 UCSF GRCh37 17 7578275 7578275 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec somatic WXS Sanger Illumina HiSeq 46 31 43 0 ENST00000269305.4:c.574C>T p.Gln192Ter p.Q192* ENST00000269305 NM_001126112.2 192 Cag/Tag 0 +TP53BP2 UCSF GRCh37 1 223971997 223971997 + synonymous_variant Silent SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 97 11 84 0 ENST00000343537.7:c.3183C>A p.Gly1061= p.G1061= ENST00000343537 NM_001031685.2 1061 ggC/ggA 0 +TP53I13 UCSF GRCh37 17 27898940 27898940 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 99 65 67 0 ENST00000301057.7:c.378C>T p.Ala126= p.A126= ENST00000301057 NM_138349.2 126 gcC/gcT 0 +TP53INP1 UCSF GRCh37 8 95953109 95953109 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 38 60 0 ENST00000342697.4:c.61C>T p.Pro21Ser p.P21S ENST00000342697 NM_033285.3 21 Cca/Tca 0 +TP63 UCSF GRCh37 3 189587118 189587118 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 37 16 45 0 ENST00000264731.3:c.1135C>T p.Arg379Cys p.R379C ENST00000264731 NM_003722.4 379 Cgt/Tgt 0 +TPM3 UCSF GRCh37 1 154164488 154164488 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 56 43 84 0 ENST00000368530.2:c.7G>A p.Glu3Lys p.E3K ENST00000368530 NM_152263.3 3 Gag/Aag 0 +TPM3 UCSF GRCh37 1 154163740 154163740 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 68 31 82 0 ENST00000368530.2:c.165G>A p.Glu55= p.E55= ENST00000368530 NM_152263.3 55 gaG/gaA 0 +TPR UCSF GRCh37 1 186331971 186331971 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 71 31 45 0 ENST00000367478.4:c.694G>A p.Glu232Lys p.E232K ENST00000367478 NM_003292.2 232 Gag/Aag 0 +TPTE UCSF GRCh37 21 10907015 10907015 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 132 20 75 0 ENST00000361285.4:c.1546G>A p.Asp516Asn p.D516N ENST00000361285 NM_199261.2 516 Gat/Aat 0 +TRAF3 UCSF GRCh37 14 103371743 103371743 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 104 12 40 0 ENST00000560371.1:c.1329G>A p.Gln443= p.Q443= ENST00000560371 NM_145725.2 443 caG/caA 0 +TRAM1L1 UCSF GRCh37 4 118006308 118006308 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 80 49 56 0 ENST00000310754.4:c.242C>T p.Ala81Val p.A81V ENST00000310754 NM_152402.2 81 gCc/gTc 0 +TRDN UCSF GRCh37 6 123581772 123581772 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 19 41 0 ENST00000398178.3:c.1816G>A p.Glu606Lys p.E606K ENST00000398178 NM_006073.3 606 Gaa/Aaa 0 +TRERF1 UCSF GRCh37 6 42224797 42224797 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 41 88 0 ENST00000372922.4:c.2380C>T p.Leu794Phe p.L794F ENST00000372922 NM_033502.2 794 Ctc/Ttc 0 +TRIM16 UCSF GRCh37 17 15554749 15554749 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 88 63 0 ENST00000455584.2:c.175G>A p.Asp59Asn p.D59N ENST00000455584 59 Gac/Aac 0 +TRIM28 UCSF GRCh37 19 59061156 59061156 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 39 64 69 0 ENST00000253024.5:c.2035G>A p.Asp679Asn p.D679N ENST00000253024 NM_005762.2 679 Gat/Aat 0 +TRIM3 UCSF GRCh37 11 6472289 6472289 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 10 16 27 0 ENST00000525074.1:c.1703C>T p.Thr568Ile p.T568I ENST00000525074 NM_001248006.1 568 aCc/aTc 0 +TRIM42 UCSF GRCh37 3 140419730 140419730 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 17 43 0 ENST00000286349.3:c.2086G>A p.Val696Met p.V696M ENST00000286349 NM_152616.4 696 Gtg/Atg 0 +TRIM50 UCSF GRCh37 7 72732893 72732893 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 135 50 65 0 ENST00000333149.2:c.654C>T p.Thr218= p.T218= ENST00000333149 NM_001281450.1 218 acC/acT 0 +TRIM50 UCSF GRCh37 7 72732686 72732686 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 107 39 68 0 ENST00000333149.2:c.749G>A p.Arg250Lys p.R250K ENST00000333149 NM_001281450.1 250 aGa/aAa 0 +TRIM56 UCSF GRCh37 7 100732393 100732393 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 188 54 41 0 ENST00000306085.6:c.1800G>A p.Gly600= p.G600= ENST00000306085 NM_030961.1 600 ggG/ggA 0 +TRIM60 UCSF GRCh37 4 165962326 165962326 + stop_gained Nonsense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 22 47 104 0 ENST00000512596.1:c.1102C>T p.Gln368Ter p.Q368* ENST00000512596 NM_152620.2 368 Caa/Taa 0 +TRIM67 UCSF GRCh37 1 231299572 231299572 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 15 9 8 0 ENST00000366653.5:c.857G>A p.Gly286Asp p.G286D ENST00000366653 286 gGc/gAc 0 +TRIOBP UCSF GRCh37 22 38121128 38121128 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 78 165 0 ENST00000406386.3:c.2565G>A p.Gln855= p.Q855= ENST00000406386 NM_001039141.2 855 caG/caA 0 +TRMT12 UCSF GRCh37 8 125463712 125463712 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 103 78 76 0 ENST00000328599.3:c.544G>A p.Asp182Asn p.D182N ENST00000328599 NM_017956.3 182 Gat/Aat 0 +TRPA1 UCSF GRCh37 8 72973889 72973889 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 50 83 0 ENST00000262209.4:c.915C>T p.Thr305= p.T305= ENST00000262209 NM_007332.2 305 acC/acT 0 +TRPC3 UCSF GRCh37 4 122853901 122853901 + missense_variant Missense_Mutation SNP T T G NOVEL P05_Rec Untested WXS Illumina HiSeq 98 82 33 0 ENST00000379645.3:c.512A>C p.Asn171Thr p.N171T ENST00000379645 NM_001130698.1 171 aAc/aCc 0 +TRPM2 UCSF GRCh37 21 45815341 45815341 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 89 35 67 0 ENST00000397928.1:c.1839C>T p.Gly613= p.G613= ENST00000397928 NM_003307.3 613 ggC/ggT 0 +TRPM3 UCSF GRCh37 9 73376591 73376591 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 35 37 55 0 ENST00000377110.3:c.1198A>G p.Thr400Ala p.T400A ENST00000377110 400 Act/Gct 0 +TRPM3 UCSF GRCh37 9 73426129 73426129 + intron_variant Intron SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 37 22 19 0 ENST00000377110.3:c.973+16634C>T *325* ENST00000377110 0 +TRPM6 UCSF GRCh37 9 77400854 77400854 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 151 41 108 0 ENST00000360774.1:c.2855G>A p.Arg952Gln p.R952Q ENST00000360774 NM_017662.4 952 cGg/cAg 0 +TRPM6 UCSF GRCh37 9 77418721 77418721 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 97 52 94 0 ENST00000360774.1:c.1720T>C p.Tyr574His p.Y574H ENST00000360774 NM_017662.4 574 Tac/Cac 0 +TRPV2 UCSF GRCh37 17 16320991 16320991 + synonymous_variant Silent SNP A A C NOVEL P05_Rec Untested WXS Illumina HiSeq 54 21 49 0 ENST00000338560.7:c.9A>C p.Ser3= p.S3= ENST00000338560 NM_016113.4 3 tcA/tcC 0 +TRRAP UCSF GRCh37 7 98579453 98579453 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 17 11 13 0 ENST00000359863.4:c.8675C>T p.Ala2892Val p.A2892V ENST00000359863 NM_001244580.1 2892 gCc/gTc 0 +TSGA10IP UCSF GRCh37 11 65721163 65721163 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 58 42 32 0 ENST00000532620.1:n.1508G>A *503* ENST00000532620 0 +TSHZ2 UCSF GRCh37 20 51871740 51871740 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 124 78 107 0 ENST00000371497.5:c.1743G>A p.Lys581= p.K581= ENST00000371497 NM_173485.5 581 aaG/aaA 0 +TSHZ3 UCSF GRCh37 19 31768537 31768537 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 42 49 0 ENST00000240587.4:c.2162C>T p.Pro721Leu p.P721L ENST00000240587 NM_020856.2 721 cCt/cTt 0 +TSPAN12 UCSF GRCh37 7 120428745 120428745 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 237 123 118 0 ENST00000222747.3:c.819T>C p.Cys273= p.C273= ENST00000222747 NM_012338.3 273 tgT/tgC 0 +TSSK3 UCSF GRCh37 1 32829360 32829360 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 51 38 50 0 ENST00000373534.3:c.310G>A p.Gly104Arg p.G104R ENST00000373534 NM_052841.3 104 Ggg/Agg 0 +TTBK1 UCSF GRCh37 6 43220535 43220535 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 23 44 0 ENST00000259750.4:c.167C>T p.Thr56Ile p.T56I ENST00000259750 NM_032538.1 56 aCc/aTc 0 +TTC21B UCSF GRCh37 2 166747022 166747022 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 33 41 0 ENST00000243344.7:c.3230G>A p.Gly1077Asp p.G1077D ENST00000243344 NM_024753.4 1077 gGt/gAt 0 +TTC3 UCSF GRCh37 21 38572625 38572625 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 17 34 0 ENST00000399017.2:c.5943G>A p.Gly1981= p.G1981= ENST00000399017 NM_003316.3 1981 ggG/ggA 0 +TTC37 UCSF GRCh37 5 94852056 94852056 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 21 43 0 ENST00000358746.2:c.2634+1G>A p.X878_splice ENST00000358746 NM_014639.3 0 +TTC7A UCSF GRCh37 2 47205951 47205951 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 63 125 0 ENST00000319190.5:c.669G>A p.Ser223= p.S223= ENST00000319190 NM_020458.2 223 tcG/tcA 0 +TTC7A UCSF GRCh37 2 47222302 47222302 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 17 53 0 ENST00000319190.5:c.1029G>A p.Glu343= p.E343= ENST00000319190 NM_020458.2 343 gaG/gaA 0 +TTN UCSF GRCh37 2 179436688 179436688 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 154 74 98 0 ENST00000589042.1:c.74171C>T p.Thr24724Ile p.T24724I ENST00000589042 NM_001267550.1 24724 aCt/aTt 0 +TTN UCSF GRCh37 2 179438831 179438831 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 176 92 164 0 ENST00000589042.1:c.72028C>T p.Pro24010Ser p.P24010S ENST00000589042 NM_001267550.1 24010 Cca/Tca 0 +TTN UCSF GRCh37 2 179464157 179464157 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 140 106 141 0 ENST00000589042.1:c.56363C>T p.Pro18788Leu p.P18788L ENST00000589042 NM_001267550.1 18788 cCa/cTa 0 +TTN UCSF GRCh37 2 179448415 179448415 + missense_variant Missense_Mutation SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 95 45 64 0 ENST00000589042.1:c.65494T>C p.Phe21832Leu p.F21832L ENST00000589042 NM_001267550.1 21832 Ttt/Ctt 0 +TTYH2 UCSF GRCh37 17 72233571 72233571 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 47 32 64 0 ENST00000269346.4:c.553C>T p.Leu185Phe p.L185F ENST00000269346 NM_032646.5 185 Ctc/Ttc 0 +TUBA3D UCSF GRCh37 2 132237810 132237810 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 159 48 136 0 ENST00000321253.6:c.544G>A p.Val182Met p.V182M ENST00000321253 NM_080386.3 182 Gtg/Atg 0 +TUBA8 UCSF GRCh37 22 18607059 18607059 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 42 22 27 0 ENST00000330423.3:c.363C>T p.Arg121= p.R121= ENST00000330423 NM_018943.2 121 cgC/cgT 0 +TUBB1 UCSF GRCh37 20 57599701 57599701 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 91 68 80 0 ENST00000217133.1:c.1219G>A p.Glu407Lys p.E407K ENST00000217133 NM_030773.3 407 Gaa/Aaa 0 +TUBB6 UCSF GRCh37 18 12325470 12325470 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 182 109 92 0 ENST00000317702.5:c.682C>T p.Leu228= p.L228= ENST00000317702 228 Ctg/Ttg 0 +TUBG1 UCSF GRCh37 17 40762482 40762482 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 20 76 0 ENST00000251413.3:c.204C>T p.Asp68= p.D68= ENST00000251413 NM_001070.4 68 gaC/gaT 0 +TUT1 UCSF GRCh37 11 62349040 62349040 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 45 19 27 0 ENST00000308436.7:c.521C>T p.Ser174Phe p.S174F ENST00000308436 NM_022830.2 174 tCc/tTc 0 +TUT1 UCSF GRCh37 11 62349173 62349173 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 15 14 8 0 ENST00000308436.7:c.388G>A p.Gly130Arg p.G130R ENST00000308436 NM_022830.2 130 Gga/Aga 0 +TXNDC15 UCSF GRCh37 5 134223596 134223596 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 23 32 0 ENST00000358387.4:c.315G>A p.Val105= p.V105= ENST00000358387 NM_024715.3 105 gtG/gtA 0 +TXNIP UCSF GRCh37 1 145441183 145441183 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 44 77 0 ENST00000369317.4:c.1141G>A p.Val381Met p.V381M ENST00000369317 NM_006472.4 381 Gtg/Atg 0 +TYW1B UCSF GRCh37 7 72178617 72178617 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 160 81 99 0 ENST00000435769.2:c.1333C>T p.Leu445Phe p.L445F ENST00000435769 NM_001145440.1 445 Ctt/Ttt 0 +U2SURP UCSF GRCh37 3 142739511 142739511 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 102 83 146 0 ENST00000473835.2:c.709G>A p.Asp237Asn p.D237N ENST00000473835 NM_001080415.1 237 Gat/Aat 0 +U2SURP UCSF GRCh37 3 142741787 142741787 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 41 74 0 ENST00000473835.2:c.1111G>A p.Glu371Lys p.E371K ENST00000473835 NM_001080415.1 371 Gaa/Aaa 0 +UACA UCSF GRCh37 15 70960077 70960077 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 77 120 0 ENST00000322954.6:c.2946G>A p.Lys982= p.K982= ENST00000322954 NM_018003.2 982 aaG/aaA 0 +UBA2 UCSF GRCh37 19 34957828 34957828 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 28 19 45 0 ENST00000246548.4:c.1650C>T p.Ala550= p.A550= ENST00000246548 NM_005499.2 550 gcC/gcT 0 +UBE2D1 UCSF GRCh37 10 60127692 60127692 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 30 26 65 0 ENST00000373910.4:c.314C>T p.Ser105Phe p.S105F ENST00000373910 NM_003338.4 105 tCc/tTc 0 +UBE2H UCSF GRCh37 7 129592377 129592377 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 138 52 33 0 ENST00000355621.3:c.19G>A p.Gly7Ser p.G7S ENST00000355621 NM_003344.3 7 Ggc/Agc 0 +UBE3A UCSF GRCh37 15 25616065 25616065 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 33 51 0 ENST00000397954.2:c.1265G>A p.Gly422Asp p.G422D ENST00000397954 422 gGt/gAt 0 +UBE3B UCSF GRCh37 12 109947520 109947520 + splice_donor_variant Splice_Site SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 44 62 0 ENST00000342494.3:c.1741+1G>A p.X581_splice ENST00000342494 NM_130466.3 0 +UBE3C UCSF GRCh37 7 157009665 157009665 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 33 23 28 0 ENST00000348165.5:c.1914G>A p.Lys638= p.K638= ENST00000348165 NM_014671.2 638 aaG/aaA 0 +UBE4A UCSF GRCh37 11 118260552 118260552 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 73 96 0 ENST00000431736.2:c.2721C>T p.Asp907= p.D907= ENST00000431736 907 gaC/gaT 0 +UBE4B UCSF GRCh37 1 10211387 10211387 + stop_gained Nonsense_Mutation SNP C C G NOVEL P05_Rec Untested WXS Illumina HiSeq 56 37 59 0 ENST00000343090.6:c.2694C>G p.Tyr898Ter p.Y898* ENST00000343090 NM_001105562.2 898 taC/taG 0 +UBQLN4 UCSF GRCh37 1 156021538 156021538 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 75 25 61 0 ENST00000368309.3:c.219G>A p.Lys73= p.K73= ENST00000368309 NM_020131.3 73 aaG/aaA 0 +UBR2 UCSF GRCh37 6 42657402 42657402 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 153 80 122 0 ENST00000372899.1:c.5120G>A p.Gly1707Glu p.G1707E ENST00000372899 NM_015255.2 1707 gGa/gAa 0 +UBR4 UCSF GRCh37 1 19454142 19454142 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 137 77 114 0 ENST00000375254.3:c.9203C>T p.Ser3068Phe p.S3068F ENST00000375254 NM_020765.2 3068 tCt/tTt 0 +UFL1 UCSF GRCh37 6 97001376 97001376 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 15 38 0 ENST00000369278.4:c.2382G>A p.Glu794= p.E794= ENST00000369278 NM_015323.4 794 gaG/gaA 0 +UGDH UCSF GRCh37 4 39511484 39511484 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 36 37 0 ENST00000316423.6:c.707C>T p.Ser236Phe p.S236F ENST00000316423 NM_001184701.1 236 tCc/tTc 0 +UGGT1 UCSF GRCh37 2 128877945 128877945 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 104 74 101 0 ENST00000259253.6:c.888C>T p.Asp296= p.D296= ENST00000259253 NM_020120.3 296 gaC/gaT 0 +UHRF1 UCSF GRCh37 19 4954743 4954743 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 78 57 33 0 ENST00000592666.1:n.2615G>A *872* ENST00000592666 0 +ULK3 UCSF GRCh37 15 75132638 75132638 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 9 12 11 0 ENST00000440863.2:c.633C>T p.Pro211= p.P211= ENST00000440863 NM_001099436.1 211 ccC/ccT 0 +UMODL1 UCSF GRCh37 21 43531503 43531503 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 34 39 19 0 ENST00000408989.2:c.2171G>A p.Ser724Asn p.S724N ENST00000408989 NM_173568.3 724 aGc/aAc 0 +UPF2 UCSF GRCh37 10 11984663 11984663 + splice_donor_variant Splice_Site SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 27 49 0 ENST00000356352.2:c.3378+1G>A p.X1126_splice ENST00000356352 0 +USH2A UCSF GRCh37 1 215848163 215848163 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 38 27 73 0 ENST00000307340.3:c.13090C>T p.Leu4364Phe p.L4364F ENST00000307340 NM_206933.2 4364 Ctt/Ttt 0 +USP1 UCSF GRCh37 1 62910585 62910585 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 57 92 0 ENST00000339950.4:c.734G>A p.Gly245Asp p.G245D ENST00000339950 NM_003368.4 245 gGt/gAt 0 +USP2 UCSF GRCh37 11 119227929 119227929 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 6 11 11 0 ENST00000260187.2:c.1698G>A p.Gly566= p.G566= ENST00000260187 NM_004205.4 566 ggG/ggA 0 +USP24 UCSF GRCh37 1 55591413 55591413 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 91 56 90 0 ENST00000294383.6:c.3654G>A p.Met1218Ile p.M1218I ENST00000294383 NM_015306.2 1218 atG/atA 0 +USP24 UCSF GRCh37 1 55612626 55612626 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 160 68 117 0 ENST00000294383.6:c.2226G>A p.Gln742= p.Q742= ENST00000294383 NM_015306.2 742 caG/caA 0 +USP28 UCSF GRCh37 11 113700020 113700020 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 64 38 75 0 ENST00000003302.4:c.958G>A p.Val320Ile p.V320I ENST00000003302 NM_020886.2 320 Gta/Ata 0 +USP35 UCSF GRCh37 11 77907395 77907395 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 53 29 12 0 ENST00000529308.1:c.104G>A p.Arg35His p.R35H ENST00000529308 NM_020798.2 35 cGt/cAt 0 +USP35 UCSF GRCh37 11 77921413 77921413 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 157 77 37 0 ENST00000529308.1:c.2512G>A p.Ala838Thr p.A838T ENST00000529308 NM_020798.2 838 Gct/Act 0 +USP37 UCSF GRCh37 2 219319679 219319679 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 87 49 82 0 ENST00000258399.3:c.2914G>A p.Gly972Arg p.G972R ENST00000258399 NM_020935.2 972 Ggg/Agg 0 +USP46 UCSF GRCh37 4 53492238 53492238 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 215 27 107 0 ENST00000441222.3:c.508G>A p.Glu170Lys p.E170K ENST00000441222 NM_022832.3 170 Gag/Aag 0 +USP6 UCSF GRCh37 17 5073988 5073988 + synonymous_variant Silent SNP C C T snp132_rs16964010 P05_Rec Untested WXS Illumina HiSeq 104 74 148 0 ENST00000574788.1:c.3732C>T p.Ser1244= p.S1244= ENST00000574788 1244 agC/agT 0 +USP6NL UCSF GRCh37 10 11523793 11523793 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 127 69 134 0 ENST00000277575.5:c.1105G>A p.Ala369Thr p.A369T ENST00000277575 NM_001080491.2 369 Gca/Aca 0 +USPL1 UCSF GRCh37 13 31227426 31227426 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 67 95 0 ENST00000255304.4:c.1380G>A p.Trp460Ter p.W460* ENST00000255304 NM_005800.4 460 tgG/tgA 0 +UTRN UCSF GRCh37 6 144863953 144863953 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 31 9 14 0 ENST00000367545.3:c.6542C>T p.Thr2181Ile p.T2181I ENST00000367545 NM_007124.2 2181 aCc/aTc 0 +VARS2 UCSF GRCh37 6 30890318 30890318 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 84 56 91 0 ENST00000541562.1:c.2114G>A p.Gly705Glu p.G705E ENST00000541562 NM_001167734.1 705 gGg/gAg 0 +VAV2 UCSF GRCh37 9 136635609 136635609 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 131 46 33 0 ENST00000371850.3:c.2238C>T p.Tyr746= p.Y746= ENST00000371850 NM_001134398.1 746 taC/taT 0 +VIL1 UCSF GRCh37 2 219300072 219300072 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 26 14 31 0 ENST00000248444.5:c.1741G>A p.Glu581Lys p.E581K ENST00000248444 NM_007127.2 581 Gag/Aag 0 +VIPAR UCSF GRCh37 14 77917622 77917622 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 123 74 126 0 ENST00000553888.1:c.251G>A p.Gly84Glu p.G84E ENST00000553888 NM_022067.3 84 gGg/gAg 0 +VIPAR UCSF GRCh37 14 77920421 77920421 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 40 27 54 0 ENST00000553888.1:c.25G>A p.Glu9Lys p.E9K ENST00000553888 NM_022067.3 9 Gag/Aag 0 +VMO1 UCSF GRCh37 17 4689213 4689213 + intron_variant Intron SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 122 65 83 0 ENST00000328739.5:c.311+19G>A *104* ENST00000328739 NM_182566.2 0 +VN1R5 UCSF GRCh37 1 247420069 247420069 + non_coding_transcript_exon_variant RNA SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 113 76 165 0 ENST00000472952.2:n.696T>C *232* ENST00000472952 0 +VPS11 UCSF GRCh37 11 118938649 118938649 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 71 51 36 0 ENST00000300793.6:c.115G>A p.Ala39Thr p.A39T ENST00000300793 NM_021729.4 39 Gct/Act 0 +VPS11 UCSF GRCh37 11 118950010 118950010 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 16 37 0 ENST00000300793.6:c.2435G>A p.Ser812Asn p.S812N ENST00000300793 NM_021729.4 812 aGt/aAt 0 +VPS13B UCSF GRCh37 8 100866404 100866404 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 44 37 53 0 ENST00000358544.2:c.10862G>A p.Arg3621Lys p.R3621K ENST00000358544 NM_017890.4 3621 aGa/aAa 0 +VPS13B UCSF GRCh37 8 100523518 100523518 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 51 86 0 ENST00000358544.2:c.4486G>A p.Ala1496Thr p.A1496T ENST00000358544 NM_017890.4 1496 Gca/Aca 0 +VPS13C UCSF GRCh37 15 62269303 62269303 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 58 33 43 0 ENST00000261517.5:c.2386G>A p.Glu796Lys p.E796K ENST00000261517 NM_020821.2 796 Gaa/Aaa 0 +VPS8 UCSF GRCh37 3 184742165 184742165 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 27 31 63 0 ENST00000437079.3:c.4044C>T p.Pro1348= p.P1348= ENST00000437079 NM_001009921.2 1348 ccC/ccT 0 +VWA5B2 UCSF GRCh37 3 183959043 183959043 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 19 9 0 ENST00000426955.2:c.3031G>A p.Gly1011Arg p.G1011R ENST00000426955 NM_138345.1 1011 Ggg/Agg 0 +WAPAL UCSF GRCh37 10 88203119 88203119 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 30 72 0 ENST00000298767.5:c.3324C>T p.Ala1108= p.A1108= ENST00000298767 NM_015045.2 1108 gcC/gcT 0 +WDFY3 UCSF GRCh37 4 85716108 85716108 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 29 18 31 0 ENST00000295888.4:c.3192C>T p.Ala1064= p.A1064= ENST00000295888 NM_014991.4 1064 gcC/gcT 0 +WDR24 UCSF GRCh37 16 739343 739343 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 54 44 25 0 ENST00000293883.4:c.298G>A p.Val100Ile p.V100I ENST00000293883 NM_032259.2 100 Gtc/Atc 0 +WDR3 UCSF GRCh37 1 118483801 118483801 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 35 70 0 ENST00000349139.5:c.844G>A p.Val282Ile p.V282I ENST00000349139 NM_006784.2 282 Gtt/Att 0 +WDR44 UCSF GRCh37 X 117532428 117532428 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 77 28 83 0 ENST00000254029.3:c.1269G>A p.Gln423= p.Q423= ENST00000254029 NM_019045.4 423 caG/caA 0 +WDR47 UCSF GRCh37 1 109553812 109553812 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.00091 P05_Rec Untested WXS Illumina HiSeq 247 157 208 0 ENST00000400794.3:c.877C>T p.Pro293Ser p.P293S ENST00000400794 293 Cct/Tct 0 +WDR49 UCSF GRCh37 3 167293884 167293884 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 54 45 60 0 ENST00000308378.3:c.308C>T p.Ser103Phe p.S103F ENST00000308378 NM_178824.3 103 tCt/tTt 0 +WDR52 UCSF GRCh37 3 113082355 113082355 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 25 15 26 0 ENST00000393845.2:c.2740C>T p.Pro914Ser p.P914S ENST00000393845 NM_001164496.1 914 Cca/Tca 0 +WDR60 UCSF GRCh37 7 158715093 158715093 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 320 76 179 0 ENST00000407559.3:c.1947C>T p.Thr649= p.T649= ENST00000407559 NM_018051.4 649 acC/acT 0 +WDR65 UCSF GRCh37 1 43685208 43685208 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 46 36 63 0 ENST00000372492.4:c.2247G>A p.Gln749= p.Q749= ENST00000372492 NM_001195831.2 749 caG/caA 0 +WDR7 UCSF GRCh37 18 54362355 54362355 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 72 61 94 0 ENST00000254442.3:c.1283G>A p.Gly428Glu p.G428E ENST00000254442 NM_015285.2 428 gGa/gAa 0 +WDR72 UCSF GRCh37 15 53908093 53908093 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 126 68 132 0 ENST00000396328.1:c.2310G>A p.Lys770= p.K770= ENST00000396328 NM_182758.3 770 aaG/aaA 0 +WDR75 UCSF GRCh37 2 190327356 190327356 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 52 91 0 ENST00000314761.4:c.925C>T p.His309Tyr p.H309Y ENST00000314761 NM_032168.1 309 Cac/Tac 0 +WDR87 UCSF GRCh37 19 38378524 38378524 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 109 61 66 0 ENST00000303868.5:c.5670G>A p.Gln1890= p.Q1890= ENST00000303868 NM_031951.3 1890 caG/caA 0 +WDR90 UCSF GRCh37 16 716093 716093 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 97 54 33 0 ENST00000293879.4:c.4578G>A p.Val1526= p.V1526= ENST00000293879 1526 gtG/gtA 0 +WDR92 UCSF GRCh37 2 68361836 68361836 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 24 48 0 ENST00000295121.6:c.864G>A p.Lys288= p.K288= ENST00000295121 NM_138458.3 288 aaG/aaA 0 +WHSC1 UCSF GRCh37 4 1956990 1956990 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 63 35 34 0 ENST00000382891.5:c.2441C>T p.Thr814Ile p.T814I ENST00000382891 NM_133335.3 814 aCt/aTt 0 +WIPF3 UCSF GRCh37 7 29918679 29918679 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 161 32 67 0 ENST00000409290.1:c.278G>A p.Ser93Asn p.S93N ENST00000409290 NM_001080529.2 93 aGc/aAc 0 +WISP1 UCSF GRCh37 8 134239825 134239825 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 50 77 0 ENST00000250160.6:c.976G>A p.Asp326Asn p.D326N ENST00000250160 NM_003882.3 326 Gat/Aat 0 +WNK1 UCSF GRCh37 12 970338 970338 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 279 90 132 0 ENST00000315939.6:c.1780G>A p.Glu594Lys p.E594K ENST00000315939 NM_018979.3 594 Gaa/Aaa 0 +WNT10A UCSF GRCh37 2 219746931 219746931 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 52 32 43 0 ENST00000258411.3:c.162G>A p.Val54= p.V54= ENST00000258411 NM_025216.2 54 gtG/gtA 0 +WNT11 UCSF GRCh37 11 75907610 75907610 + missense_variant Missense_Mutation SNP G G T NOVEL P05_Rec Untested WXS Illumina HiSeq 154 18 40 0 ENST00000322563.3:c.236C>A p.Ala79Asp p.A79D ENST00000322563 NM_004626.2 79 gCc/gAc 0 +WNT2B UCSF GRCh37 1 113051913 113051913 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 8 11 0 ENST00000369684.4:c.29C>T p.Ala10Val p.A10V ENST00000369684 NM_024494.2 10 gCt/gTt 0 +WRN UCSF GRCh37 8 30921871 30921871 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 92 49 88 0 ENST00000298139.5:c.276G>A p.Gly92= p.G92= ENST00000298139 NM_000553.4 92 ggG/ggA 0 +WWC1 UCSF GRCh37 5 167858422 167858422 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 19 6 40 0 ENST00000521089.1:c.2253C>T p.Thr751= p.T751= ENST00000521089 751 acC/acT 0 +XIRP1 UCSF GRCh37 3 39227263 39227263 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 40 15 8 0 ENST00000340369.3:c.3674C>T p.Thr1225Ile p.T1225I ENST00000340369 NM_194293.2 1225 aCc/aTc 0 +XPO7 UCSF GRCh37 8 21853052 21853052 + missense_variant Missense_Mutation SNP C C A NOVEL P05_Rec Untested WXS Illumina HiSeq 113 63 109 0 ENST00000252512.9:c.2287C>A p.His763Asn p.H763N ENST00000252512 NM_015024.4 763 Cat/Aat 0 +XPOT UCSF GRCh37 12 64819211 64819211 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 60 57 0 ENST00000332707.5:c.1546G>A p.Glu516Lys p.E516K ENST00000332707 NM_007235.4 516 Gaa/Aaa 0 +XRCC1 UCSF GRCh37 19 44050777 44050777 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 79 45 82 0 ENST00000262887.5:c.1396G>A p.Glu466Lys p.E466K ENST00000262887 466 Gaa/Aaa 0 +XRCC6 UCSF GRCh37 22 42046737 42046737 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 18 30 93 0 ENST00000359308.4:c.971G>A p.Ser324Asn p.S324N ENST00000359308 324 aGt/aAt 0 +XYLB UCSF GRCh37 3 38407160 38407160 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 63 29 24 0 ENST00000207870.3:c.440G>A p.Arg147His p.R147H ENST00000207870 NM_005108.3 147 cGc/cAc 0 +XYLB UCSF GRCh37 3 38420763 38420763 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 70 10 52 0 ENST00000207870.3:c.1221G>A p.Glu407= p.E407= ENST00000207870 NM_005108.3 407 gaG/gaA 0 +YIF1B UCSF GRCh37 19 38796082 38796082 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 22 12 11 0 ENST00000339413.6:c.855C>T p.Ala285= p.A285= ENST00000339413 NM_001039673.2 285 gcC/gcT 0 +YLPM1 UCSF GRCh37 14 75265287 75265287 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 35 84 0 ENST00000325680.7:c.3287G>A p.Gly1096Asp p.G1096D ENST00000325680 NM_019589.2 1096 gGt/gAt 0 +ZAN UCSF GRCh37 7 100345790 100345790 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 53 25 67 0 ENST00000546292.1:c.1054C>T p.Pro352Ser p.P352S ENST00000546292 NM_173059.1 352 Cca/Tca 0 +ZAN UCSF GRCh37 7 100382390 100382390 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 102 35 56 0 ENST00000546292.1:c.6765G>A p.Leu2255= p.L2255= ENST00000546292 NM_173059.1 2255 ctG/ctA 0 +ZBTB11 UCSF GRCh37 3 101384318 101384318 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 49 65 91 0 ENST00000312938.4:c.1113G>A p.Leu371= p.L371= ENST00000312938 NM_014415.3 371 ttG/ttA 0 +ZBTB40 UCSF GRCh37 1 22834591 22834591 + missense_variant Missense_Mutation SNP G G C NOVEL P05_Rec Untested WXS Illumina HiSeq 36 24 39 0 ENST00000404138.1:c.1458G>C p.Met486Ile p.M486I ENST00000404138 NM_001083621.1 486 atG/atC 0 +ZC3H14 UCSF GRCh37 14 89038484 89038484 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 60 31 75 0 ENST00000251038.5:c.346C>T p.Pro116Ser p.P116S ENST00000251038 NM_024824.4 116 Cca/Tca 0 +ZC3H7A UCSF GRCh37 16 11868307 11868307 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 69 37 76 0 ENST00000396516.2:c.688G>A p.Val230Ile p.V230I ENST00000396516 230 Gtt/Att 0 +ZC3HC1 UCSF GRCh37 7 129691065 129691065 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 73 31 48 0 ENST00000358303.4:c.142G>A p.Asp48Asn p.D48N ENST00000358303 NM_016478.3 48 Gac/Aac 0 +ZCCHC11 UCSF GRCh37 1 52991465 52991465 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 189 111 113 0 ENST00000257177.4:c.488G>A p.Gly163Glu p.G163E ENST00000257177 163 gGa/gAa 0 +ZCCHC14 UCSF GRCh37 16 87446357 87446357 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 192 68 74 0 ENST00000268616.4:c.1559G>A p.Ser520Asn p.S520N ENST00000268616 NM_015144.2 520 aGc/aAc 0 +ZCCHC14 UCSF GRCh37 16 87454311 87454311 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 42 13 20 0 ENST00000268616.4:c.441C>T p.Leu147= p.L147= ENST00000268616 NM_015144.2 147 ctC/ctT 0 +ZCCHC5 UCSF GRCh37 X 77913462 77913462 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 21 43 0 ENST00000321110.1:c.456G>A p.Glu152= p.E152= ENST00000321110 NM_152694.2 152 gaG/gaA 0 +ZCCHC8 UCSF GRCh37 12 122968055 122968055 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 154 60 82 0 ENST00000336229.4:c.557C>T p.Pro186Leu p.P186L ENST00000336229 NM_017612.3 186 cCg/cTg 0 +ZDBF2 UCSF GRCh37 2 207170065 207170065 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 143 76 95 0 ENST00000374423.3:c.813G>A p.Leu271= p.L271= ENST00000374423 NM_020923.1 271 ttG/ttA 0 +ZDHHC19 UCSF GRCh37 3 195935277 195935277 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 31 25 36 0 ENST00000296326.3:c.563C>T p.Ser188Phe p.S188F ENST00000296326 NM_001039617.1 188 tCc/tTc 0 +ZEB2 UCSF GRCh37 2 145157589 145157589 + stop_gained Nonsense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 150 53 80 0 ENST00000558170.2:c.1165A>T p.Lys389Ter p.K389* ENST00000558170 NM_014795.3 389 Aaa/Taa 0 +ZFAND2B UCSF GRCh37 2 220072104 220072104 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 73 59 47 0 ENST00000289528.5:c.111G>A p.Val37= p.V37= ENST00000289528 NM_001270999.1 37 gtG/gtA 0 +ZFAT UCSF GRCh37 8 135669891 135669891 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 36 17 58 0 ENST00000377838.3:c.109G>A p.Glu37Lys p.E37K ENST00000377838 NM_020863.3 37 Gaa/Aaa 0 +ZFHX2 UCSF GRCh37 14 24002825 24002825 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 150 93 106 0 ENST00000419474.3:c.1710G>A p.Gln570= p.Q570= ENST00000419474 NM_033400.2 570 caG/caA 0 +ZFP106 UCSF GRCh37 15 42731479 42731479 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 110 77 137 0 ENST00000263805.4:c.4227G>A p.Glu1409= p.E1409= ENST00000263805 NM_022473.1 1409 gaG/gaA 0 +ZFP37 UCSF GRCh37 9 115805715 115805715 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 105 65 138 0 ENST00000374227.3:c.1183C>T p.His395Tyr p.H395Y ENST00000374227 395 Cat/Tat 0 +ZFP90 UCSF GRCh37 16 68597932 68597932 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 111 46 77 0 ENST00000570495.1:c.1242G>A p.Arg414= p.R414= ENST00000570495 414 agG/agA 0 +ZFPM2 UCSF GRCh37 8 106814052 106814052 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 213 120 228 0 ENST00000407775.2:c.1742C>T p.Ser581Phe p.S581F ENST00000407775 NM_012082.3 581 tCc/tTc 0 +ZFR UCSF GRCh37 5 32385715 32385715 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 91 49 67 0 ENST00000265069.8:c.2540C>T p.Ser847Phe p.S847F ENST00000265069 NM_016107.3 847 tCt/tTt 0 +ZFR2 UCSF GRCh37 19 3823333 3823333 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 81 38 51 0 ENST00000262961.4:c.1282G>A p.Gly428Ser p.G428S ENST00000262961 NM_015174.1 428 Ggt/Agt 0 +ZFR2 UCSF GRCh37 19 3823340 3823340 + missense_variant Missense_Mutation SNP T T A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 35 48 0 ENST00000262961.4:c.1275A>T p.Lys425Asn p.K425N ENST00000262961 NM_015174.1 425 aaA/aaT 0 +ZGPAT UCSF GRCh37 20 62340026 62340026 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 62 37 10 0 ENST00000328969.5:c.94G>A p.Glu32Lys p.E32K ENST00000328969 NM_032527.4 32 Gag/Aag 0 +ZIK1 UCSF GRCh37 19 58096347 58096347 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 32 40 47 0 ENST00000597850.1:c.61G>A p.Asp21Asn p.D21N ENST00000597850 NM_001010879.2 21 Gac/Aac 0 +ZMAT5 UCSF GRCh37 22 30136704 30136704 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 7 13 10 0 ENST00000397781.3:c.206G>A p.Gly69Asp p.G69D ENST00000397781 NM_019103.2 69 gGc/gAc 0 +ZMYM5 UCSF GRCh37 13 20426330 20426330 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 158 84 160 0 ENST00000382905.4:c.-10G>A p.X4_splice ENST00000382905 NM_001039650.2 0 +ZNF192 UCSF GRCh37 6 28116513 28116513 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 79 74 95 0 ENST00000330236.6:c.328C>T p.Leu110= p.L110= ENST00000330236 NM_001278122.1 110 Ctg/Ttg 0 +ZNF212 UCSF GRCh37 7 148947384 148947384 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 166 85 87 0 ENST00000335870.2:c.159G>A p.Lys53= p.K53= ENST00000335870 NM_012256.3 53 aaG/aaA 0 +ZNF217 UCSF GRCh37 20 52193739 52193739 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 86 65 82 0 ENST00000371471.2:c.1564C>T p.His522Tyr p.H522Y ENST00000371471 522 Cac/Tac 0 +ZNF276 UCSF GRCh37 16 89793686 89793686 + splice_acceptor_variant Splice_Site SNP G G A snp132_rs35924380 P05_Rec Untested WXS Illumina HiSeq 93 33 49 0 ENST00000443381.2:c.1007-1G>A p.X336_splice ENST00000443381 NM_001113525.1 0 +ZNF282 UCSF GRCh37 7 148895596 148895596 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 133 64 51 0 ENST00000262085.3:c.337G>A p.Asp113Asn p.D113N ENST00000262085 NM_003575.2 113 Gat/Aat 0 +ZNF287 UCSF GRCh37 17 16456380 16456380 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 124 60 96 0 ENST00000395824.1:c.1076G>A p.Arg359Lys p.R359K ENST00000395824 359 aGg/aAg 0 +ZNF319 UCSF GRCh37 16 58031145 58031145 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 126 50 31 0 ENST00000299237.2:c.1025C>T p.Pro342Leu p.P342L ENST00000299237 NM_020807.1 342 cCc/cTc 0 +ZNF323 UCSF GRCh37 6 28297340 28297340 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 120 69 102 0 ENST00000414429.1:c.121C>T p.Leu41Phe p.L41F ENST00000414429 41 Ctt/Ttt 0 +ZNF324 UCSF GRCh37 19 58982849 58982849 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 13 37 33 0 ENST00000536459.2:c.990G>A p.Arg330= p.R330= ENST00000536459 330 cgG/cgA 0 +ZNF333 UCSF GRCh37 19 14827864 14827864 + stop_gained Nonsense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 13 7 12 0 ENST00000292530.6:c.786G>A p.Trp262Ter p.W262* ENST00000292530 NM_032433.2 262 tgG/tgA 0 +ZNF335 UCSF GRCh37 20 44587967 44587967 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 48 43 30 0 ENST00000322927.2:c.2126G>A p.Gly709Glu p.G709E ENST00000322927 NM_022095.3 709 gGg/gAg 0 +ZNF337 UCSF GRCh37 20 25657391 25657391 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 146 85 168 0 ENST00000376436.1:c.533G>A p.Gly178Glu p.G178E ENST00000376436 178 gGa/gAa 0 +ZNF35 UCSF GRCh37 3 44701118 44701118 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.011,1000g2011may_all_0.0223,snp132_rs116792244 P05_Rec Untested WXS Illumina HiSeq 73 29 44 0 ENST00000396056.2:c.1263C>T p.Ser421= p.S421= ENST00000396056 NM_003420.3 421 agC/agT 0 +ZNF394 UCSF GRCh37 7 99092124 99092124 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 122 53 92 0 ENST00000337673.6:c.714C>T p.Thr238= p.T238= ENST00000337673 NM_032164.2 238 acC/acT 0 +ZNF407 UCSF GRCh37 18 72347340 72347340 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 103 65 85 0 ENST00000299687.5:c.4365C>T p.Thr1455= p.T1455= ENST00000299687 NM_017757.2 1455 acC/acT 0 +ZNF415 UCSF GRCh37 19 53612377 53612377 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 85 38 78 0 ENST00000500065.4:c.921G>A p.Lys307= p.K307= ENST00000500065 NM_001136038.2 307 aaG/aaA 0 +ZNF441 UCSF GRCh37 19 11890937 11890937 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 74 46 100 0 ENST00000357901.4:c.298G>A p.Val100Ile p.V100I ENST00000357901 NM_152355.2 100 Gta/Ata 0 +ZNF441 UCSF GRCh37 19 11891501 11891501 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 134 61 135 0 ENST00000357901.4:c.862G>A p.Ala288Thr p.A288T ENST00000357901 NM_152355.2 288 Gca/Aca 0 +ZNF442 UCSF GRCh37 19 12461660 12461660 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 204 123 241 0 ENST00000242804.4:c.739C>T p.Pro247Ser p.P247S ENST00000242804 NM_030824.2 247 Cct/Tct 0 +ZNF467 UCSF GRCh37 7 149467538 149467538 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 50 16 30 0 ENST00000302017.3:c.142G>A p.Val48Met p.V48M ENST00000302017 NM_207336.1 48 Gtg/Atg 0 +ZNF467 UCSF GRCh37 7 149462662 149462662 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 49 10 8 0 ENST00000302017.3:c.929C>T p.Thr310Met p.T310M ENST00000302017 NM_207336.1 310 aCg/aTg 0 +ZNF48 UCSF GRCh37 16 30409098 30409098 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 64 46 36 0 ENST00000320159.2:c.527G>A p.Gly176Asp p.G176D ENST00000320159 NM_152652.2 176 gGt/gAt 0 +ZNF490 UCSF GRCh37 19 12692278 12692278 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 120 60 133 0 ENST00000311437.6:c.611C>T p.Thr204Ile p.T204I ENST00000311437 NM_020714.2 204 aCt/aTt 0 +ZNF490 UCSF GRCh37 19 12692468 12692468 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 83 60 99 0 ENST00000311437.6:c.421C>T p.Pro141Ser p.P141S ENST00000311437 NM_020714.2 141 Cct/Tct 0 +ZNF506 UCSF GRCh37 19 19917874 19917874 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 159 95 135 0 ENST00000443905.2:c.7C>T p.Pro3Ser p.P3S ENST00000443905 3 Cca/Tca 0 +ZNF532 UCSF GRCh37 18 56651271 56651271 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 48 80 0 ENST00000336078.4:c.3479C>T p.Thr1160Ile p.T1160I ENST00000336078 NM_018181.4 1160 aCt/aTt 0 +ZNF536 UCSF GRCh37 19 30936483 30936483 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 78 54 21 0 ENST00000355537.3:c.2014C>T p.Arg672Cys p.R672C ENST00000355537 NM_014717.1 672 Cgt/Tgt 0 +ZNF536 UCSF GRCh37 19 30935391 30935391 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 184 93 67 0 ENST00000355537.3:c.922G>A p.Ala308Thr p.A308T ENST00000355537 NM_014717.1 308 Gcg/Acg 0 +ZNF541 UCSF GRCh37 19 48047518 48047518 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 35 28 14 0 ENST00000314121.4:c.2268C>T p.Gly756= p.G756= ENST00000314121 756 ggC/ggT 0 +ZNF554 UCSF GRCh37 19 2834574 2834574 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 55 25 75 0 ENST00000317243.5:c.1341C>T p.Asp447= p.D447= ENST00000317243 NM_001102651.1 447 gaC/gaT 0 +ZNF557 UCSF GRCh37 19 7083018 7083018 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 65 35 81 0 ENST00000414706.1:c.556G>A p.Gly186Arg p.G186R ENST00000414706 NM_024341.2 186 Ggg/Agg 0 +ZNF560 UCSF GRCh37 19 9577475 9577475 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 63 153 0 ENST00000301480.4:c.2148C>T p.Asp716= p.D716= ENST00000301480 NM_152476.2 716 gaC/gaT 0 +ZNF561 UCSF GRCh37 19 9727769 9727769 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 125 62 144 0 ENST00000302851.3:c.193C>T p.Leu65Phe p.L65F ENST00000302851 NM_152289.2 65 Ctc/Ttc 0 +ZNF585B UCSF GRCh37 19 37677650 37677650 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 146 83 137 0 ENST00000532828.2:c.789C>T p.Ile263= p.I263= ENST00000532828 NM_152279.3 263 atC/atT 0 +ZNF615 UCSF GRCh37 19 52497163 52497163 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 81 41 78 0 ENST00000594083.1:c.1199C>T p.Thr400Ile p.T400I ENST00000594083 400 aCa/aTa 0 +ZNF620 UCSF GRCh37 3 40557693 40557693 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 90 28 69 0 ENST00000314529.6:c.608G>A p.Arg203Lys p.R203K ENST00000314529 NM_175888.3 203 aGa/aAa 0 +ZNF620 UCSF GRCh37 3 40557846 40557846 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 116 33 88 0 ENST00000314529.6:c.761G>A p.Cys254Tyr p.C254Y ENST00000314529 NM_175888.3 254 tGt/tAt 0 +ZNF624 UCSF GRCh37 17 16527505 16527505 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 88 56 76 0 ENST00000311331.7:c.695C>T p.Thr232Ile p.T232I ENST00000311331 NM_020787.3 232 aCa/aTa 0 +ZNF626 UCSF GRCh37 19 20829188 20829188 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 162 99 165 0 ENST00000601440.1:c.27G>A p.Val9= p.V9= ENST00000601440 NM_001076675.2 9 gtG/gtA 0 +ZNF644 UCSF GRCh37 1 91404482 91404482 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 100 45 95 0 ENST00000370440.1:c.2429G>A p.Arg810Lys p.R810K ENST00000370440 810 aGa/aAa 0 +ZNF648 UCSF GRCh37 1 182026564 182026564 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 34 23 15 0 ENST00000339948.3:c.582G>A p.Arg194= p.R194= ENST00000339948 NM_001009992.1 194 agG/agA 0 +ZNF648 UCSF GRCh37 1 182026690 182026690 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 68 39 45 0 ENST00000339948.3:c.456C>T p.Tyr152= p.Y152= ENST00000339948 NM_001009992.1 152 taC/taT 0 +ZNF653 UCSF GRCh37 19 11597911 11597911 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 90 45 46 0 ENST00000293771.5:c.1234G>A p.Ala412Thr p.A412T ENST00000293771 NM_138783.3 412 Gca/Aca 0 +ZNF707 UCSF GRCh37 8 144773782 144773782 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 26 16 18 0 ENST00000532205.1:c.155C>T p.Pro52Leu p.P52L ENST00000532205 NM_001288805.1 52 cCc/cTc 0 +ZNF709 UCSF GRCh37 19 12576377 12576377 + missense_variant Missense_Mutation SNP T T C NOVEL P05_Rec Untested WXS Illumina HiSeq 101 44 95 0 ENST00000397732.3:c.359A>G p.His120Arg p.H120R ENST00000397732 NM_152601.3 120 cAc/cGc 0 +ZNF729 UCSF GRCh37 19 22498434 22498434 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 147 104 115 0 ENST00000601693.1:c.2215C>T p.Pro739Ser p.P739S ENST00000601693 739 Ccc/Tcc 0 +ZNF778 UCSF GRCh37 16 89294111 89294111 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 191 79 152 0 ENST00000433976.2:c.1331C>T p.Thr444Ile p.T444I ENST00000433976 NM_001201407.1 444 aCt/aTt 0 +ZNF780A UCSF GRCh37 19 40581410 40581410 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 254 137 214 0 ENST00000455521.1:c.942C>T p.Ala314= p.A314= ENST00000455521 NM_001142577.1 314 gcC/gcT 0 +ZNF813 UCSF GRCh37 19 53994800 53994800 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 144 102 197 0 ENST00000396403.4:c.1314C>T p.Pro438= p.P438= ENST00000396403 NM_001004301.3 438 ccC/ccT 0 +ZNF831 UCSF GRCh37 20 57767550 57767550 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 46 29 25 0 ENST00000371030.2:c.1476C>T p.Leu492= p.L492= ENST00000371030 NM_178457.2 492 ctC/ctT 0 +ZNF831 UCSF GRCh37 20 57829381 57829381 + synonymous_variant Silent SNP A A G NOVEL P05_Rec Untested WXS Illumina HiSeq 42 27 55 0 ENST00000371030.2:c.4617A>G p.Ala1539= p.A1539= ENST00000371030 NM_178457.2 1539 gcA/gcG 0 +ZNF836 UCSF GRCh37 19 52658807 52658807 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 174 96 148 0 ENST00000322146.8:c.2129C>T p.Ala710Val p.A710V ENST00000322146 NM_001102657.1 710 gCa/gTa 0 +ZNF837 UCSF GRCh37 19 58879530 58879530 + synonymous_variant Silent SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 11 7 10 0 ENST00000427624.2:c.1170C>T p.Pro390= p.P390= ENST00000427624 390 ccC/ccT 0 +ZNF862 UCSF GRCh37 7 149558563 149558563 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 66 34 29 0 ENST00000223210.4:c.2314G>A p.Ala772Thr p.A772T ENST00000223210 NM_001099220.1 772 Gcg/Acg 0 +ZNHIT2 UCSF GRCh37 11 64884272 64884272 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 65 28 19 0 ENST00000310597.4:c.854G>A p.Gly285Glu p.G285E ENST00000310597 NM_014205.2 285 gGg/gAg 0 +ZPBP UCSF GRCh37 7 49977150 49977150 + missense_variant Missense_Mutation SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 105 30 61 0 ENST00000046087.2:c.1030G>A p.Val344Met p.V344M ENST00000046087 NM_007009.2 344 Gtg/Atg 0 +ZPBP2 UCSF GRCh37 17 38028615 38028615 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 52 25 41 0 ENST00000348931.4:c.499C>T p.Leu167= p.L167= ENST00000348931 NM_199321.2 167 Ctg/Ttg 0 +ZSCAN10 UCSF GRCh37 16 3142594 3142594 + synonymous_variant Silent SNP C C T NOVEL P05_Rec Untested WXS Illumina HiSeq 23 12 12 0 ENST00000252463.2:c.180G>A p.Val60= p.V60= ENST00000252463 NM_032805.1 60 gtG/gtA 0 +ZSCAN21 UCSF GRCh37 7 99662011 99662011 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 99 22 68 0 ENST00000292450.4:c.1193G>A p.Ser398Asn p.S398N ENST00000292450 NM_145914.2 398 aGt/aAt 0 +ZSCAN5A UCSF GRCh37 19 56733035 56733035 + missense_variant Missense_Mutation SNP G G A NOVEL P05_Rec Untested WXS Illumina HiSeq 36 61 101 0 ENST00000587340.1:c.1400C>T p.Pro467Leu p.P467L ENST00000587340 467 cCc/cTc 0 +FAM22G UCSF GRCh37 9 99697718 99697718 + synonymous_variant Silent SNP T T C snp132_rs2479289 P06_Pri Untested WXS Illumina HiSeq 24 5 27 1 ENST00000372322.3:c.822T>C p.Ile274= p.I274= ENST00000372322 NM_001170741.1 274 atT/atC 0 +GZMH UCSF GRCh37 14 25076836 25076836 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.053,snp132_rs41469548 P06_Pri Untested WXS Illumina HiSeq 28 7 53 1 ENST00000216338.4:c.321C>T p.Asn107= p.N107= ENST00000216338 NM_033423.4 107 aaC/aaT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P06_Pri Untested WXS Illumina HiSeq 40 13 45 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +RFPL1 UCSF GRCh37 22 29837847 29837847 + synonymous_variant Silent SNP G G C 1000g2010nov_all_0.077,snp132_rs61734564 P06_Pri Untested WXS Illumina HiSeq 27 6 35 1 ENST00000354373.2:c.690G>C p.Thr230= p.T230= ENST00000354373 NM_021026.2 230 acG/acC 0 +APOB UCSF GRCh37 2 21241986 21241986 + splice_acceptor_variant Splice_Site SNP C C A NOVEL P06_Rec Untested WXS Illumina HiSeq 74 9 82 0 ENST00000233242.1:c.3000-1G>T p.X1000_splice ENST00000233242 NM_000384.2 0 +ATRX UCSF GRCh37 X 76875862 76875865 + splice_donor_variant,coding_sequence_variant Splice_Site DEL CACT CACT - NOVEL P06_Rec Untested WXS Illumina HiSeq 46 0 ENST00000373344.5:c.5270_5272+1del p.X1757_splice ENST00000373344 NM_000489.3 1757 0 +CFTR UCSF GRCh37 7 117188850 117188850 + synonymous_variant Silent SNP G G T snp132_rs79074685 P06_Rec Untested WXS Illumina HiSeq 32 5 20 1 ENST00000003084.6:c.1365G>T p.Ala455= p.A455= ENST00000003084 NM_000492.3 455 gcG/gcT 0 +DNAJB4 UCSF GRCh37 1 78479131 78479131 + missense_variant Missense_Mutation SNP A A G NOVEL P06_Rec Untested WXS Illumina HiSeq 72 36 96 0 ENST00000370763.5:c.608A>G p.Glu203Gly p.E203G ENST00000370763 NM_007034.3 203 gAg/gGg 0 +DSC1 UCSF GRCh37 18 28734746 28734746 + synonymous_variant Silent SNP T T C NOVEL P06_Rec Untested WXS Illumina HiSeq 36 7 50 0 ENST00000257198.5:c.618A>G p.Glu206= p.E206= ENST00000257198 NM_024421.2 206 gaA/gaG 0 +GRIN2A UCSF GRCh37 16 9984911 9984911 + stop_gained Nonsense_Mutation SNP C C A NOVEL P06_Rec Untested WXS Illumina HiSeq 75 13 105 0 ENST00000330684.3:c.1054G>T p.Glu352Ter p.E352* ENST00000330684 NM_001134407.1 352 Gag/Tag 0 +GSN UCSF GRCh37 9 124089724 124089724 + missense_variant Missense_Mutation SNP G G A NOVEL P06_Rec Untested WXS Illumina HiSeq 8 6 10 0 ENST00000373818.4:c.1879G>A p.Ala627Thr p.A627T ENST00000373818 NM_000177.4 627 Gcc/Acc 0 +HEPHL1 UCSF GRCh37 11 93844875 93844875 + missense_variant Missense_Mutation SNP C C A NOVEL P06_Rec Untested WXS Illumina HiSeq 84 44 129 0 ENST00000315765.9:c.3295C>A p.Gln1099Lys p.Q1099K ENST00000315765 NM_001098672.1 1099 Cag/Aag 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P06_Rec Untested WXS Illumina HiSeq 29 21 45 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KLHL4 UCSF GRCh37 X 86888751 86888751 + missense_variant,splice_region_variant Missense_Mutation SNP G G T NOVEL P06_Rec Untested WXS Illumina HiSeq 27 4 28 1 ENST00000373114.4:c.1552G>T p.Val518Leu p.V518L ENST00000373114 NM_057162.2 518 Gta/Tta 0 +LARS UCSF GRCh37 5 145529208 145529208 + missense_variant Missense_Mutation SNP T T C NOVEL P06_Rec Untested WXS Illumina HiSeq 107 50 174 0 ENST00000394434.2:c.1480A>G p.Ile494Val p.I494V ENST00000394434 NM_020117.9 494 Att/Gtt 0 +LILRB1 UCSF GRCh37 19 55144532 55144532 + missense_variant Missense_Mutation SNP G G A NOVEL P06_Rec Untested WXS Illumina HiSeq 23 9 34 0 ENST00000324602.7:c.1024G>A p.Val342Met p.V342M ENST00000324602 NM_001278399.1 342 Gtg/Atg 0 +PKHD1 UCSF GRCh37 6 51612824 51612824 + missense_variant Missense_Mutation SNP T T C NOVEL P06_Rec Untested WXS Illumina HiSeq 81 40 143 0 ENST00000371117.3:c.9590A>G p.Gln3197Arg p.Q3197R ENST00000371117 NM_138694.3 3197 cAg/cGg 0 +RHOA UCSF GRCh37 3 49405899 49405899 + missense_variant Missense_Mutation SNP A A G NOVEL P06_Rec Untested WXS Illumina HiSeq 47 15 70 0 ENST00000418115.1:c.239T>C p.Ile80Thr p.I80T ENST00000418115 NM_001664.2 80 aTa/aCa 0 +SKA3 UCSF GRCh37 13 21746601 21746601 + frameshift_variant Frame_Shift_Del DEL G G - 1000g2010nov_all P06_Rec Untested WXS Illumina HiSeq 6 0 ENST00000314759.5:c.208delC p.Gln70LysfsTer7 p.Q70Kfs*7 ENST00000314759 NM_145061.5 70 Caa/aa 0 +SLC26A4 UCSF GRCh37 7 107329599 107329599 + missense_variant Missense_Mutation SNP G G A NOVEL P06_Rec Untested WXS Illumina HiSeq 46 21 80 0 ENST00000265715.3:c.1103G>A p.Gly368Glu p.G368E ENST00000265715 NM_000441.1 368 gGa/gAa 0 +SOX6 UCSF GRCh37 11 16007844 16007844 + missense_variant Missense_Mutation SNP T T C NOVEL P06_Rec Untested WXS Illumina HiSeq 99 13 101 0 ENST00000396356.3:c.2029A>G p.Thr677Ala p.T677A ENST00000396356 NM_033326.3 677 Acc/Gcc 0 +TP53 UCSF GRCh37 17 7577120 7577120 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.000,snp132_rs28934576 P06_Rec somatic WXS Sanger Illumina HiSeq 3 18 27 0 ENST00000269305.4:c.818G>A p.Arg273His p.R273H ENST00000269305 NM_001126112.2 273 cGt/cAt 0 +UBQLNL UCSF GRCh37 11 5537008 5537008 + missense_variant Missense_Mutation SNP G G C NOVEL P06_Rec Untested WXS Illumina HiSeq 79 42 112 0 ENST00000380184.1:c.664C>G p.Leu222Val p.L222V ENST00000380184 NM_145053.4 222 Cta/Gta 0 +ULK2 UCSF GRCh37 17 19729500 19729500 + splice_acceptor_variant Splice_Site SNP C C G NOVEL P06_Rec Untested WXS Illumina HiSeq 32 23 65 0 ENST00000395544.4:c.788-1G>C p.X263_splice ENST00000395544 NM_014683.3 0 +ZIC5 UCSF GRCh37 13 100617663 100617663 + missense_variant Missense_Mutation SNP C C T NOVEL P06_Rec Untested WXS Illumina HiSeq 21 6 21 0 ENST00000267294.4:c.1960G>A p.Gly654Arg p.G654R ENST00000267294 NM_033132.3 654 Ggg/Agg 0 +ZNF283 UCSF GRCh37 19 44352107 44352107 + missense_variant Missense_Mutation SNP A A G NOVEL P06_Rec Untested WXS Illumina HiSeq 139 57 166 0 ENST00000324461.7:c.1354A>G p.Ile452Val p.I452V ENST00000324461 NM_181845.1 452 Atc/Gtc 0 +AGAP1 UCSF GRCh37 2 237028849 237028849 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 94 13 49 0 ENST00000304032.8:c.2128C>T p.Arg710Trp p.R710W ENST00000304032 NM_001037131.2 710 Cgg/Tgg 0 +ALOX15 UCSF GRCh37 17 4542894 4542894 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.047,snp132_rs3894312 P07_Pri Untested WXS Illumina HiSeq 80 9 45 1 ENST00000570836.1:c.168T>C p.Tyr56= p.Y56= ENST00000570836 56 taT/taC 0 +ANK2 UCSF GRCh37 4 114213580 114213580 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 12 5 19 0 ENST00000357077.4:c.2286C>A p.Tyr762Ter p.Y762* ENST00000357077 NM_001148.4 762 taC/taA 0 +AP2A2 UCSF GRCh37 11 1009101 1009101 + missense_variant,splice_region_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 33 20 48 1 ENST00000448903.2:c.2422T>G p.Tyr808Asp p.Y808D ENST00000448903 NM_012305.3 808 Tat/Gat 0 +ARNT UCSF GRCh37 1 150801579 150801579 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 76 13 113 0 ENST00000358595.5:c.1157A>C p.Tyr386Ser p.Y386S ENST00000358595 NM_178427.2 386 tAc/tCc 0 +ASPM UCSF GRCh37 1 197097775 197097775 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 92 16 115 0 ENST00000367409.4:c.2781G>T p.Leu927Phe p.L927F ENST00000367409 NM_018136.4 927 ttG/ttT 0 +ASPM UCSF GRCh37 1 197097791 197097791 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 66 27 100 0 ENST00000367409.4:c.2765G>A p.Ser922Asn p.S922N ENST00000367409 NM_018136.4 922 aGt/aAt 0 +ATAD3A UCSF GRCh37 1 1451415 1451415 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 38 31 64 0 ENST00000378755.5:c.229C>G p.Leu77Val p.L77V ENST00000378755 NM_018188.3 77 Ctg/Gtg 0 +ATP6V1A UCSF GRCh37 3 113508669 113508669 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 82 11 86 0 ENST00000273398.3:c.970G>A p.Glu324Lys p.E324K ENST00000273398 NM_001690.3 324 Gaa/Aaa 0 +ATRX UCSF GRCh37 X 76912145 76912145 + splice_acceptor_variant Splice_Site SNP T T C NOVEL P07_Pri somatic WXS Sanger Illumina HiSeq 41 15 56 0 ENST00000373344.5:c.4121-2A>G p.X1374_splice ENST00000373344 NM_000489.3 0 +ATRX UCSF GRCh37 X 76937485 76937485 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 78 86 83 0 ENST00000373344.5:c.3263G>C p.Gly1088Ala p.G1088A ENST00000373344 NM_000489.3 1088 gGt/gCt 0 +ATRX UCSF GRCh37 X 76937487 76937487 + stop_gained Nonsense_Mutation SNP A A T NOVEL P07_Pri Untested WXS Illumina HiSeq 77 87 83 0 ENST00000373344.5:c.3261T>A p.Tyr1087Ter p.Y1087* ENST00000373344 NM_000489.3 1087 taT/taA 0 +ATRX UCSF GRCh37 X 76937376 76937376 + synonymous_variant Silent SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 77 99 112 0 ENST00000373344.5:c.3372T>C p.Ser1124= p.S1124= ENST00000373344 NM_000489.3 1124 tcT/tcC 0 +BMF UCSF GRCh37 15 40396521 40396521 + missense_variant Missense_Mutation SNP G G A snp132_rs77642791 P07_Pri Untested WXS Illumina HiSeq 95 20 117 0 ENST00000354670.4:c.313C>T p.Pro105Ser p.P105S ENST00000354670 NM_001003940.1 105 Cct/Tct 0 +C15orf17 UCSF GRCh37 15 75194971 75194971 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 91 12 103 0 ENST00000357635.5:c.586A>C p.Thr196Pro p.T196P ENST00000357635 NM_020447.3 196 Acc/Ccc 0 +C1orf172 UCSF GRCh37 1 27276560 27276560 + stop_lost Nonstop_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 31 5 42 0 ENST00000320567.5:c.1197A>C p.Ter399TyrextTer19 p.*399Yext*19 ENST00000320567 NM_152365.2 399 taA/taC 0 +C2orf65 UCSF GRCh37 2 74787345 74787345 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri somatic WXS Sanger Illumina HiSeq 38 26 51 0 ENST00000290536.5:c.1355T>G p.Leu452Arg p.L452R ENST00000290536 NM_138804.4 452 cTg/cGg 0 +C3 UCSF GRCh37 19 6697740 6697740 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 68 10 62 0 ENST00000245907.6:c.2506C>A p.Pro836Thr p.P836T ENST00000245907 NM_000064.2 836 Ccc/Acc 0 +C8orf80 UCSF GRCh37 8 27903051 27903051 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 128 28 106 0 ENST00000413272.2:c.1439A>C p.Asn480Thr p.N480T ENST00000413272 NM_001010906.1 480 aAc/aCc 0 +CAND1 UCSF GRCh37 12 67675701 67675701 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 111 16 102 0 ENST00000545606.1:c.80C>A p.Thr27Lys p.T27K ENST00000545606 NM_018448.3 27 aCa/aAa 0 +CBLL1 UCSF GRCh37 7 107399173 107399176 + protein_altering_variant In_Frame_Del DEL ACCA ACCA C NOVEL P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000440859.3:c.1026_1029delinsC p.Pro350del p.P350del ENST00000440859 NM_024814.2 342 gcACCA/gcC 0 +CCDC27 UCSF GRCh37 1 3680383 3680383 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 20 7 41 0 ENST00000294600.2:c.1435C>A p.Gln479Lys p.Q479K ENST00000294600 NM_152492.2 479 Caa/Aaa 0 +CHRNA2 UCSF GRCh37 8 27327497 27327497 + splice_region_variant,synonymous_variant Splice_Region SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 29 19 41 1 ENST00000407991.1:c.75T>G p.Gly25= p.G25= ENST00000407991 NM_000742.3 25 ggT/ggG 0 +CNTLN UCSF GRCh37 9 17486994 17486995 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P07_Pri Untested WXS Illumina HiSeq 25 0 ENST00000380647.3:c.4054dup p.Thr1352AsnfsTer4 p.T1352Nfs*4 ENST00000380647 1350 gaa/gaAa 0 +COIL UCSF GRCh37 17 55028118 55028119 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P07_Pri Untested WXS Illumina HiSeq 7 0 ENST00000240316.4:c.485dup p.Asn162LysfsTer6 p.N162Kfs*6 ENST00000240316 NM_004645.2 162 aac/aAac 0 +COL5A1 UCSF GRCh37 9 137642705 137642705 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 13 7 20 1 ENST00000371817.3:c.1639C>A p.Gln547Lys p.Q547K ENST00000371817 NM_001278074.1 547 Caa/Aaa 0 +CPNE3 UCSF GRCh37 8 87563330 87563330 + splice_donor_variant Splice_Site SNP T T G 1000g2011may_all_0.0465 P07_Pri Untested WXS Illumina HiSeq 56 35 103 1 ENST00000521271.1:c.1068+2T>G p.X356_splice ENST00000521271 NM_003909.3 0 +CYP26B1 UCSF GRCh37 2 72359514 72359514 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 17 7 31 2 ENST00000001146.2:c.1381A>C p.Thr461Pro p.T461P ENST00000001146 NM_019885.3 461 Acc/Ccc 0 +DDX26B UCSF GRCh37 X 134703307 134703307 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 59 75 81 0 ENST00000370752.4:c.1238G>A p.Arg413Gln p.R413Q ENST00000370752 NM_182540.4 413 cGa/cAa 0 +DEFB126 UCSF GRCh37 20 126310 126311 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P07_Pri Untested WXS Illumina HiSeq 9 0 ENST00000382398.3:c.313_314del p.Thr105ProfsTer? p.T105Pfs*? ENST00000382398 NM_030931.3 105 ACc/c 0 +DIXDC1 UCSF GRCh37 11 111853109 111853109 + frameshift_variant,splice_region_variant Frame_Shift_Ins INS T T CC NOVEL P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000440460.2:c.813delinsCC p.Gly272ArgfsTer44 p.G272Rfs*44 ENST00000440460 NM_001037954.3 271 ccT/ccCC 0 +DLEC1 UCSF GRCh37 3 38162039 38162040 + frameshift_variant Frame_Shift_Del DEL GA GA - 1000g2010nov_all P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000308059.6:c.4815_4816del p.Glu1605AspfsTer29 p.E1605Dfs*29 ENST00000308059 1602 gGA/g 0 +DNM1 UCSF GRCh37 9 131009679 131009679 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 22 6 24 0 ENST00000372923.3:c.1807C>G p.Leu603Val p.L603V ENST00000372923 NM_004408.2 603 Ctg/Gtg 0 +DTX2 UCSF GRCh37 7 76131644 76131644 + synonymous_variant Silent SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 47 6 18 0 ENST00000324432.5:c.1260C>T p.Ser420= p.S420= ENST00000324432 NM_020892.2 420 tcC/tcT 0 +DYRK1B UCSF GRCh37 19 40316909 40316909 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 47 11 64 0 ENST00000593685.1:c.1429T>C p.Ser477Pro p.S477P ENST00000593685 477 Tcc/Ccc 0 +EML6 UCSF GRCh37 2 55177866 55177866 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 139 23 83 1 ENST00000356458.6:c.4163A>G p.Asp1388Gly p.D1388G ENST00000356458 NM_001039753.2 1388 gAc/gGc 0 +ERAL1 UCSF GRCh37 17 27182065 27182065 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 30 6 52 0 ENST00000254928.5:c.13A>C p.Ser5Arg p.S5R ENST00000254928 NM_005702.2 5 Agc/Cgc 0 +ERBB2IP UCSF GRCh37 5 65374262 65374262 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 82 21 100 0 ENST00000506030.1:c.4164C>A p.Tyr1388Ter p.Y1388* ENST00000506030 1388 taC/taA 0 +EXD3 UCSF GRCh37 9 140289784 140289784 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 18 4 25 0 ENST00000340951.4:c.26A>C p.Asp9Ala p.D9A ENST00000340951 NM_017820.3 9 gAc/gCc 0 +FAM53B UCSF GRCh37 10 126311912 126311912 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 16 6 37 0 ENST00000337318.3:c.1168A>G p.Arg390Gly p.R390G ENST00000337318 NM_014661.3 390 Aga/Gga 0 +FCER1A UCSF GRCh37 1 159275786 159275786 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 86 17 115 0 ENST00000368115.1:c.340C>G p.Leu114Val p.L114V ENST00000368115 NM_002001.3 114 Ctc/Gtc 0 +FLNA UCSF GRCh37 X 153579992 153579992 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 25 4 25 0 ENST00000369850.3:c.6980C>T p.Ser2327Phe p.S2327F ENST00000369850 NM_001110556.1 2327 tCt/tTt 0 +FLT4 UCSF GRCh37 5 180058762 180058762 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 22 5 29 0 ENST00000261937.6:c.75C>A p.Tyr25Ter p.Y25* ENST00000261937 NM_182925.4 25 taC/taA 0 +FMN1 UCSF GRCh37 15 33261341 33261341 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 53 39 70 1 ENST00000334528.9:c.1892T>C p.Leu631Pro p.L631P ENST00000334528 NM_001103184.3 631 cTc/cCc 0 +GCLM UCSF GRCh37 1 94354629 94354629 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 83 10 104 0 ENST00000370238.3:c.742C>A p.Leu248Met p.L248M ENST00000370238 NM_002061.2 248 Ctg/Atg 0 +GGT1 UCSF GRCh37 22 25011077 25011077 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 53 8 45 0 ENST00000400382.1:c.365C>T p.Ser122Leu p.S122L ENST00000400382 NM_001288833.1 122 tCg/tTg 0 +GGT1 UCSF GRCh37 22 25011062 25011062 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.010 P07_Pri Untested WXS Illumina HiSeq 66 9 46 1 ENST00000400382.1:c.350C>G p.Thr117Ser p.T117S ENST00000400382 NM_001288833.1 117 aCc/aGc 0 +GGTLC2 UCSF GRCh37 22 22988913 22988913 + missense_variant Missense_Mutation SNP T T A 1000g2011may_all_0.0159,snp132_rs71316771 P07_Pri Untested WXS Illumina HiSeq 26 6 16 0 ENST00000480559.1:c.98T>A p.Val33Asp p.V33D ENST00000480559 NM_199127.2 33 gTt/gAt 0 +GGTLC2 UCSF GRCh37 22 22988917 22988917 + synonymous_variant Silent SNP T T C 1000g2011may_all_0.0094,snp132_rs71316772 P07_Pri Untested WXS Illumina HiSeq 27 6 16 0 ENST00000480559.1:c.102T>C p.Asp34= p.D34= ENST00000480559 NM_199127.2 34 gaT/gaC 0 +GIGYF1 UCSF GRCh37 7 100285167 100285167 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri somatic WXS Sanger Illumina HiSeq 67 36 72 0 ENST00000275732.5:c.334G>C p.Ala112Pro p.A112P ENST00000275732 NM_022574.4 112 Gct/Cct 0 +GIMAP8 UCSF GRCh37 7 150167961 150167961 + missense_variant,splice_region_variant Missense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 77 26 61 0 ENST00000307271.3:c.681G>T p.Gln227His p.Q227H ENST00000307271 NM_175571.2 227 caG/caT 0 +GPHB5 UCSF GRCh37 14 63784413 63784414 + non_coding_transcript_exon_variant RNA INS - - C NOVEL P07_Pri Untested WXS Illumina HiSeq 8 0 ENST00000539258.1:n.207_208insG *69* ENST00000539258 0 +GRXCR1 UCSF GRCh37 4 43032401 43032401 + synonymous_variant Silent SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 135 87 120 0 ENST00000399770.2:c.717T>C p.Cys239= p.C239= ENST00000399770 NM_001080476.2 239 tgT/tgC 0 +GSTP1 UCSF GRCh37 11 67352019 67352019 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 37 10 50 0 ENST00000398606.3:c.122A>G p.Glu41Gly p.E41G ENST00000398606 NM_000852.3 41 gAg/gGg 0 +HS6ST1 UCSF GRCh37 2 129025758 129025758 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.135 P07_Pri Untested WXS Illumina HiSeq 53 7 33 1 ENST00000259241.6:c.1214G>T p.Ser405Ile p.S405I ENST00000259241 NM_004807.2 405 aGc/aTc 0 +HSF1 UCSF GRCh37 8 145534883 145534883 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 21 6 28 1 ENST00000528838.1:c.512A>G p.Glu171Gly p.E171G ENST00000528838 NM_005526.2 171 gAg/gGg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 87 57 98 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGFN1 UCSF GRCh37 1 201190723 201190723 + synonymous_variant Silent SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 40 7 39 0 ENST00000335211.4:c.10050G>C p.Pro3350= p.P3350= ENST00000335211 NM_001164586.1 3350 ccG/ccC 0 +ILK UCSF GRCh37 11 6629291 6629291 + synonymous_variant Silent SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 63 13 94 0 ENST00000396751.2:c.105C>T p.Phe35= p.F35= ENST00000396751 NM_001014795.2 35 ttC/ttT 0 +IPO5 UCSF GRCh37 13 98637679 98637679 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 119 20 118 0 ENST00000261574.5:c.230G>A p.Arg77Lys p.R77K ENST00000261574 NM_002271.4 77 aGa/aAa 0 +JAG2 UCSF GRCh37 14 105615535 105615535 + synonymous_variant Silent SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 40 10 36 1 ENST00000331782.3:c.1725C>G p.Arg575= p.R575= ENST00000331782 NM_002226.4 575 cgC/cgG 0 +KDM3A UCSF GRCh37 2 86678324 86678324 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 74 9 81 0 ENST00000409556.1:c.441G>A p.Leu147= p.L147= ENST00000409556 147 ttG/ttA 0 +KIAA1267 UCSF GRCh37 17 44144000 44144002 + inframe_deletion In_Frame_Del DEL GAT GAT - NOVEL P07_Pri Untested WXS Illumina HiSeq 8 0 ENST00000262419.6:c.1749_1751del p.Ser584del p.S584del ENST00000262419 NM_001193466.1 583 tcATCt/tct 0 +KIR2DL3 UCSF GRCh37 19 55263934 55263978 + stop_lost,3_prime_UTR_variant Nonstop_Mutation DEL TCATCGTGTACACGGAACTTCCAAATGCTGAGCCCTGATCCAAAG TCATCGTGTACACGGAACTTCCAAATGCTGAGCCCTGATCCAAAG CCACCATGTACATGGAACTTCCAAATGCTAAGCCAAGATCA NOVEL P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000342376.3:c.989_*7delinsCCACCATGTACATGGAACTTCCAAATGCTAAGCCAAGATCA *330* ENST00000342376 NM_015868.2 330 0 +KLHDC10 UCSF GRCh37 7 129765709 129765709 + missense_variant Missense_Mutation SNP A A T NOVEL P07_Pri Untested WXS Illumina HiSeq 71 32 20 0 ENST00000335420.5:c.869A>T p.His290Leu p.H290L ENST00000335420 NM_014997.3 290 cAt/cTt 0 +KLHL30 UCSF GRCh37 2 239049934 239049934 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 22 4 17 0 ENST00000409223.1:c.539T>G p.Val180Gly p.V180G ENST00000409223 180 gTc/gGc 0 +LAMA2 UCSF GRCh37 6 129824352 129824352 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 137 17 106 0 ENST00000421865.2:c.8474T>C p.Phe2825Ser p.F2825S ENST00000421865 NM_001079823.1 2825 tTc/tCc 0 +LRBA UCSF GRCh37 4 151935787 151935787 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 17 5 39 0 ENST00000357115.3:c.8G>A p.Ser3Asn p.S3N ENST00000357115 NM_006726.4 3 aGc/aAc 0 +LRIT2 UCSF GRCh37 10 85985269 85985269 + missense_variant Missense_Mutation SNP G G A snp132_rs79267836 P07_Pri Untested WXS Illumina HiSeq 78 19 80 0 ENST00000372113.4:c.8C>T p.Ser3Leu p.S3L ENST00000372113 NM_001017924.2 3 tCa/tTa 0 +LRP2 UCSF GRCh37 2 169993907 169993907 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 87 67 95 0 ENST00000263816.3:c.13615A>G p.Ile4539Val p.I4539V ENST00000263816 NM_004525.2 4539 Atc/Gtc 0 +MIS18BP1 UCSF GRCh37 14 45716019 45716020 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P07_Pri Untested WXS Illumina HiSeq 7 0 ENST00000310806.4:c.471dup p.Leu158IlefsTer8 p.L158Ifs*8 ENST00000310806 NM_018353.4 157 aaa/aaAa 0 +MLH3 UCSF GRCh37 14 75514620 75514623 + frameshift_variant Frame_Shift_Del DEL TCTG TCTG - NOVEL P07_Pri Untested WXS Illumina HiSeq 8 0 ENST00000355774.2:c.1736_1739del p.Thr579ArgfsTer30 p.T579Rfs*30 ENST00000355774 NM_001040108.1 579 aCAGAg/ag 0 +MMP16 UCSF GRCh37 8 89209512 89209512 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 106 12 83 0 ENST00000286614.6:c.156C>A p.Tyr52Ter p.Y52* ENST00000286614 NM_005941.4 52 taC/taA 0 +MYEF2 UCSF GRCh37 15 48443702 48443702 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 203 81 142 0 ENST00000324324.7:c.1274A>G p.Asn425Ser p.N425S ENST00000324324 NM_016132.3 425 aAt/aGt 0 +NINJ2 UCSF GRCh37 12 772656 772656 + synonymous_variant Silent SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 94 14 105 0 ENST00000305108.4:c.9T>G p.Gly3= p.G3= ENST00000305108 NM_016533.4 3 ggT/ggG 0 +NIPA1 UCSF GRCh37 15 23060899 23060899 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 17 4 36 0 ENST00000337435.4:c.233T>G p.Val78Gly p.V78G ENST00000337435 NM_144599.4 78 gTt/gGt 0 +NLGN4Y UCSF GRCh37 Y 16942197 16942197 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 35 7 74 0 ENST00000355905.2:c.1399A>C p.Thr467Pro p.T467P ENST00000355905 NM_014893.4 467 Acc/Ccc 0 +NME6 UCSF GRCh37 3 48340012 48340012 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 21 13 29 1 ENST00000421967.1:c.19A>G p.Ser7Gly p.S7G ENST00000421967 NM_005793.3 7 Agt/Ggt 0 +NTF4 UCSF GRCh37 19 49564944 49564944 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 19 9 33 1 ENST00000301411.3:c.311T>G p.Val104Gly p.V104G ENST00000301411 NM_006179.4 104 gTg/gGg 0 +NVL UCSF GRCh37 1 224455754 224455754 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 49 9 57 0 ENST00000281701.6:c.2164G>C p.Ala722Pro p.A722P ENST00000281701 NM_002533.3 722 Gca/Cca 0 +OAF UCSF GRCh37 11 120099649 120099649 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 22 14 32 1 ENST00000328965.4:c.620T>G p.Val207Gly p.V207G ENST00000328965 NM_178507.2 207 gTg/gGg 0 +PIEZO1 UCSF GRCh37 16 88786118 88786118 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 20 6 37 0 ENST00000301015.9:c.6335T>G p.Val2112Gly p.V2112G ENST00000301015 NM_001142864.2 2112 gTg/gGg 0 +PKHD1 UCSF GRCh37 6 51920409 51920409 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 57 13 75 0 ENST00000371117.3:c.1812C>T p.Gly604= p.G604= ENST00000371117 NM_138694.3 604 ggC/ggT 0 +PRKDC UCSF GRCh37 8 48866910 48866910 + frameshift_variant Frame_Shift_Del DEL T T - 1000g2010nov_all P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000314191.2:c.496del p.Ile166TyrfsTer6 p.I166Yfs*6 ENST00000314191 NM_006904.6 166 Ata/ta 0 +PRSS1 UCSF GRCh37 7 142460412 142460431 + coding_sequence_variant,intron_variant In_Frame_Del DEL ATGTCAGGTGATTTGACCAA ATGTCAGGTGATTTGACCAA CTGCCAGGTGATTTGAC NOVEL P07_Pri Untested WXS Illumina HiSeq 13 0 ENST00000311737.7:c.585_591+13delinsCTGCCAGGTGATTTGAC *195* ENST00000311737 NM_002769.4 195 0 +PRSS48 UCSF GRCh37 4 152201017 152201018 + frameshift_variant Frame_Shift_Ins INS - - GGCAG NOVEL P07_Pri Untested WXS Illumina HiSeq 9 0 ENST00000455694.2:c.123_124insGCAGG p.Gln42AlafsTer23 p.Q42Afs*23 ENST00000455694 NM_183375.2 41 tgg/tgGGCAGg 0 +PTPN3 UCSF GRCh37 9 112184987 112185008 + splice_donor_variant,coding_sequence_variant,intron_variant Splice_Site INS GGAGGACATACCAGTTGGGAGT GGAGGACATACCAGTTGGGAGT AGGAGGACATACCAGGTGGGGGG NOVEL P07_Pri Untested WXS Illumina HiSeq 7 0 ENST00000374541.2:c.1126_1136+11delinsCCCCCCACCTGGTATGTCCTCCT p.X376_splice ENST00000374541 NM_001145368.1 376 0 +RANBP3L UCSF GRCh37 5 36257584 36257584 + synonymous_variant Silent SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 70 10 77 0 ENST00000502994.1:c.819G>A p.Pro273= p.P273= ENST00000502994 NM_001161429.1 273 ccG/ccA 0 +RASIP1 UCSF GRCh37 19 49243416 49243416 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 38 6 48 0 ENST00000222145.4:c.124G>C p.Ala42Pro p.A42P ENST00000222145 NM_017805.2 42 Gca/Cca 0 +RCOR3 UCSF GRCh37 1 211452617 211452617 + missense_variant Missense_Mutation SNP A A T NOVEL P07_Pri Untested WXS Illumina HiSeq 105 32 92 0 ENST00000419091.2:c.679A>T p.Asn227Tyr p.N227Y ENST00000419091 NM_001136223.1 227 Aat/Tat 0 +RMND5A UCSF GRCh37 2 86998675 86998684 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TAACAGATTG TAACAGATTG AACAGATTA NOVEL P07_Pri Untested WXS Illumina HiSeq 7 0 ENST00000283632.4:c.958-6_961delinsAACAGATTA p.X320_splice ENST00000283632 NM_022780.3 0 +RNF123 UCSF GRCh37 3 49728916 49728916 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 51 6 47 0 ENST00000327697.6:c.141A>C p.Glu47Asp p.E47D ENST00000327697 NM_022064.3 47 gaA/gaC 0 +ROD1 UCSF GRCh37 9 115060107 115060119 + splice_donor_variant,intron_variant Splice_Site INS CTCACCATACACA CTCACCATACACA AACCCCCATAAACC NOVEL P07_Pri Untested WXS Illumina HiSeq 6 0 ENST00000458258.1:c.136+2_136+14delinsGGTTTATGGGGGTT p.X46_splice ENST00000458258 NM_001244898.1 0 +SDR42E1 UCSF GRCh37 16 82032960 82032960 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 165 62 165 0 ENST00000328945.5:c.938G>A p.Arg313His p.R313H ENST00000328945 NM_145168.2 313 cGc/cAc 0 +SEMA3A UCSF GRCh37 7 83610763 83610763 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 61 11 37 0 ENST00000265362.4:c.1526T>G p.Val509Gly p.V509G ENST00000265362 NM_006080.2 509 gTt/gGt 0 +SIGLEC12 UCSF GRCh37 19 52001516 52001516 + synonymous_variant Silent SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 49 13 82 1 ENST00000291707.3:c.1161G>C p.Ser387= p.S387= ENST00000291707 NM_053003.2 387 tcG/tcC 0 +SLC3A1 UCSF GRCh37 2 44539860 44539860 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 102 14 77 0 ENST00000260649.6:c.1468G>T p.Val490Leu p.V490L ENST00000260649 NM_000341.3 490 Gta/Tta 0 +SLC43A1 UCSF GRCh37 11 57261571 57261571 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 66 30 66 0 ENST00000278426.3:c.766A>G p.Thr256Ala p.T256A ENST00000278426 NM_003627.5 256 Acc/Gcc 0 +SLC5A10 UCSF GRCh37 17 18923739 18923739 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 52 21 65 2 ENST00000395647.2:c.1834G>C p.Ala612Pro p.A612P ENST00000395647 NM_152351.4 612 Gcc/Ccc 0 +SLC6A18 UCSF GRCh37 5 1244398 1244398 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 63 11 59 0 ENST00000324642.3:c.1406A>G p.Glu469Gly p.E469G ENST00000324642 NM_182632.2 469 gAg/gGg 0 +SLC7A14 UCSF GRCh37 3 170244714 170244714 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 37 5 53 0 ENST00000231706.5:c.12C>T p.Phe4= p.F4= ENST00000231706 NM_020949.2 4 ttC/ttT 0 +SLC7A4 UCSF GRCh37 22 21384142 21384142 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 34 19 54 0 ENST00000382932.2:c.1481G>T p.Cys494Phe p.C494F ENST00000382932 NM_004173.2 494 tGc/tTc 0 +SMYD1 UCSF GRCh37 2 88387386 88387386 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 16 9 33 0 ENST00000419482.2:c.320C>G p.Ala107Gly p.A107G ENST00000419482 NM_198274.3 107 gCg/gGg 0 +SNAP91 UCSF GRCh37 6 84315423 84315423 + synonymous_variant Silent SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 65 14 50 0 ENST00000439399.2:c.1122A>G p.Gly374= p.G374= ENST00000439399 NM_014841.2 374 ggA/ggG 0 +SPATA5 UCSF GRCh37 4 123850221 123850221 + synonymous_variant Silent SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 74 14 122 1 ENST00000274008.4:c.315A>G p.Gly105= p.G105= ENST00000274008 NM_145207.2 105 ggA/ggG 0 +SPATC1 UCSF GRCh37 8 145086738 145086738 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Pri Untested WXS Illumina HiSeq 16 11 31 0 ENST00000377470.3:c.55C>G p.Arg19Gly p.R19G ENST00000377470 NM_198572.2 19 Cgg/Ggg 0 +SRCRB4D UCSF GRCh37 7 76033635 76033635 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 55 24 56 0 ENST00000275560.3:c.122T>C p.Leu41Pro p.L41P ENST00000275560 NM_080744.1 41 cTc/cCc 0 +SUSD3 UCSF GRCh37 9 95838089 95838089 + missense_variant Missense_Mutation SNP C C A 1000g2011may_all_0.0392 P07_Pri Untested WXS Illumina HiSeq 70 12 43 0 ENST00000375472.3:c.112C>A p.Pro38Thr p.P38T ENST00000375472 NM_145006.2 38 Ccc/Acc 0 +TMEM27 UCSF GRCh37 X 15682877 15682877 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 33 4 58 1 ENST00000380342.3:c.22C>T p.Leu8= p.L8= ENST00000380342 NM_020665.5 8 Ctg/Ttg 0 +TNN UCSF GRCh37 1 175054602 175054602 + synonymous_variant Silent SNP C C A NOVEL P07_Pri Untested WXS Illumina HiSeq 8 7 34 0 ENST00000239462.4:c.1296C>A p.Gly432= p.G432= ENST00000239462 NM_022093.1 432 ggC/ggA 0 +TOR1AIP2 UCSF GRCh37 1 179820453 179820453 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 119 41 122 0 ENST00000367612.3:c.80C>T p.Ala27Val p.A27V ENST00000367612 NM_145034.4 27 gCg/gTg 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 19 87 72 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TPSD1 UCSF GRCh37 16 1307050 1307050 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.019 P07_Pri Untested WXS Illumina HiSeq 27 11 32 1 ENST00000211076.3:c.507C>T p.Asp169= p.D169= ENST00000211076 NM_012217.2 169 gaC/gaT 0 +TPST2 UCSF GRCh37 22 26937357 26937357 + synonymous_variant Silent SNP G G T NOVEL P07_Pri Untested WXS Illumina HiSeq 39 5 30 1 ENST00000338754.4:c.240C>A p.Gly80= p.G80= ENST00000338754 NM_003595.3 80 ggC/ggA 0 +TRIM56 UCSF GRCh37 7 100732823 100732823 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 60 17 59 1 ENST00000306085.6:c.2230A>C p.Thr744Pro p.T744P ENST00000306085 NM_030961.1 744 Acc/Ccc 0 +TTF2 UCSF GRCh37 1 117622249 117622249 + synonymous_variant Silent SNP G G A NOVEL P07_Pri Untested WXS Illumina HiSeq 56 10 88 0 ENST00000369466.4:c.1761G>A p.Gln587= p.Q587= ENST00000369466 NM_003594.3 587 caG/caA 0 +TUBB6 UCSF GRCh37 18 12325728 12325728 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 82 69 105 0 ENST00000317702.5:c.940G>C p.Ala314Pro p.A314P ENST00000317702 314 Gcc/Ccc 0 +UNC13D UCSF GRCh37 17 73832988 73832988 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 43 11 67 1 ENST00000207549.4:c.1067C>G p.Ala356Gly p.A356G ENST00000207549 NM_199242.2 356 gCc/gGc 0 +UPK3BL UCSF GRCh37 7 102279621 102279621 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.034,1000g2011may_all_0.1195,snp132_rs56365279 P07_Pri Untested WXS Illumina HiSeq 14 3 10 0 ENST00000340457.8:c.511G>A p.Glu171Lys p.E171K ENST00000340457 NM_001114403.2 171 Gaa/Aaa 0 +VAX1 UCSF GRCh37 10 118893633 118893633 + synonymous_variant Silent SNP A A C NOVEL P07_Pri Untested WXS Illumina HiSeq 16 9 20 0 ENST00000369206.5:c.891T>G p.Gly297= p.G297= ENST00000369206 NM_001112704.1 297 ggT/ggG 0 +VGF UCSF GRCh37 7 100806737 100806737 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Pri Untested WXS Illumina HiSeq 16 9 22 0 ENST00000249330.2:c.1388A>C p.His463Pro p.H463P ENST00000249330 NM_003378.3 463 cAc/cCc 0 +WDR3 UCSF GRCh37 1 118502003 118502003 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Pri Untested WXS Illumina HiSeq 77 11 63 0 ENST00000349139.5:c.2765C>T p.Thr922Ile p.T922I ENST00000349139 NM_006784.2 922 aCt/aTt 0 +WHAMM UCSF GRCh37 15 83478599 83478599 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 17 9 9 0 ENST00000286760.4:c.121T>C p.Phe41Leu p.F41L ENST00000286760 NM_001080435.1 41 Ttc/Ctc 0 +YEATS2 UCSF GRCh37 3 183515780 183515780 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Pri Untested WXS Illumina HiSeq 128 22 96 0 ENST00000305135.5:c.3167A>G p.Lys1056Arg p.K1056R ENST00000305135 NM_018023.4 1056 aAa/aGa 0 +ZNF513 UCSF GRCh37 2 27601003 27601003 + synonymous_variant Silent SNP T T C NOVEL P07_Pri Untested WXS Illumina HiSeq 62 10 76 0 ENST00000323703.6:c.1035A>G p.Gly345= p.G345= ENST00000323703 NM_144631.5 345 ggA/ggG 0 +ZNF783 UCSF GRCh37 7 148978725 148978725 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Pri Untested WXS Illumina HiSeq 44 9 38 0 ENST00000434415.1:c.932G>C p.Gly311Ala p.G311A ENST00000434415 NM_001195220.1 311 gGc/gCc 0 +ABCB9 UCSF GRCh37 12 123434996 123434996 + splice_donor_variant Splice_Site SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 24 4 26 0 ENST00000542678.1:c.716+2T>G p.X239_splice ENST00000542678 0 +ABCG8 UCSF GRCh37 2 44101016 44101016 + synonymous_variant Silent SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 228 26 208 0 ENST00000272286.2:c.1302C>G p.Leu434= p.L434= ENST00000272286 NM_022437.2 434 ctC/ctG 0 +ADAMTS8 UCSF GRCh37 11 130276014 130276014 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 65 8 63 0 ENST00000257359.6:c.2109C>A p.Tyr703Ter p.Y703* ENST00000257359 NM_007037.4 703 taC/taA 0 +AGAP1 UCSF GRCh37 2 237028849 237028849 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 28 29 49 0 ENST00000304032.8:c.2128C>T p.Arg710Trp p.R710W ENST00000304032 NM_001037131.2 710 Cgg/Tgg 0 +ALDH4A1 UCSF GRCh37 1 19202933 19202933 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 18 11 48 0 ENST00000375341.3:c.1214A>G p.Glu405Gly p.E405G ENST00000375341 NM_003748.3 405 gAg/gGg 0 +ANK3 UCSF GRCh37 10 62021707 62021707 + synonymous_variant Silent SNP G G A snp132_rs79510328 P07_Rec Untested WXS Illumina HiSeq 47 8 62 0 ENST00000280772.2:c.708C>T p.Phe236= p.F236= ENST00000280772 NM_020987.3 236 ttC/ttT 0 +ANKRD33 UCSF GRCh37 12 52284892 52284892 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 93 12 67 0 ENST00000301190.6:c.1162C>A p.Gln388Lys p.Q388K ENST00000301190 NM_001130015.1 388 Caa/Aaa 0 +ARNT UCSF GRCh37 1 150801579 150801579 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 90 12 113 0 ENST00000358595.5:c.1157A>C p.Tyr386Ser p.Y386S ENST00000358595 NM_178427.2 386 tAc/tCc 0 +ASH1L UCSF GRCh37 1 155490985 155490985 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 209 30 152 0 ENST00000392403.3:c.326G>C p.Arg109Pro p.R109P ENST00000392403 NM_018489.2 109 cGa/cCa 0 +ASPM UCSF GRCh37 1 197097791 197097791 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 70 21 100 0 ENST00000367409.4:c.2765G>A p.Ser922Asn p.S922N ENST00000367409 NM_018136.4 922 aGt/aAt 0 +ATAD3A UCSF GRCh37 1 1451415 1451415 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 37 19 64 0 ENST00000378755.5:c.229C>G p.Leu77Val p.L77V ENST00000378755 NM_018188.3 77 Ctg/Gtg 0 +ATF7 UCSF GRCh37 12 53925539 53925539 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 54 11 99 1 ENST00000420353.2:c.916G>C p.Ala306Pro p.A306P ENST00000420353 NM_006856.2 306 Gcc/Ccc 0 +ATP11A UCSF GRCh37 13 113485856 113485856 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 48 31 42 0 ENST00000487903.1:c.1389C>T p.Asn463= p.N463= ENST00000487903 463 aaC/aaT 0 +ATP12A UCSF GRCh37 13 25283587 25283587 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 24 13 51 1 ENST00000218548.6:c.2597T>G p.Val866Gly p.V866G ENST00000218548 NM_001185085.1 866 gTg/gGg 0 +ATRX UCSF GRCh37 X 76912145 76912145 + splice_acceptor_variant Splice_Site SNP T T C NOVEL P07_Rec somatic WXS Sanger Illumina HiSeq 19 41 56 0 ENST00000373344.5:c.4121-2A>G p.X1374_splice ENST00000373344 NM_000489.3 0 +BACE2 UCSF GRCh37 21 42609457 42609457 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 97 25 112 0 ENST00000330333.6:c.419C>G p.Ser140Cys p.S140C ENST00000330333 NM_012105.4 140 tCc/tGc 0 +BIN2 UCSF GRCh37 12 51685455 51685455 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 79 21 72 0 ENST00000267012.4:c.1435C>T p.Pro479Ser p.P479S ENST00000267012 NM_016293.2 479 Cct/Tct 0 +BIN2 UCSF GRCh37 12 51690936 51690936 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 57 7 53 0 ENST00000267012.4:c.615C>G p.Cys205Trp p.C205W ENST00000267012 NM_016293.2 205 tgC/tgG 0 +BPTF UCSF GRCh37 17 65941584 65941584 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 73 9 66 1 ENST00000306378.6:c.6760A>C p.Thr2254Pro p.T2254P ENST00000306378 NM_182641.3 2254 Acc/Ccc 0 +C15orf17 UCSF GRCh37 15 75194971 75194971 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 84 10 103 0 ENST00000357635.5:c.586A>C p.Thr196Pro p.T196P ENST00000357635 NM_020447.3 196 Acc/Ccc 0 +C17orf46 UCSF GRCh37 17 43332527 43332527 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 44 7 52 2 ENST00000331780.4:c.1022T>C p.Leu341Pro p.L341P ENST00000331780 NM_152343.2 341 cTc/cCc 0 +C17orf46 UCSF GRCh37 17 43332520 43332520 + synonymous_variant Silent SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 66 11 50 1 ENST00000331780.4:c.1029A>C p.Pro343= p.P343= ENST00000331780 NM_152343.2 343 ccA/ccC 0 +C2orf54 UCSF GRCh37 2 241831112 241831112 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 24 6 51 0 ENST00000388934.4:c.583A>G p.Arg195Gly p.R195G ENST00000388934 NM_001085437.1 195 Aga/Gga 0 +C2orf65 UCSF GRCh37 2 74787345 74787345 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec somatic WXS Sanger Illumina HiSeq 33 8 51 0 ENST00000290536.5:c.1355T>G p.Leu452Arg p.L452R ENST00000290536 NM_138804.4 452 cTg/cGg 0 +C5orf55 UCSF GRCh37 5 442884 442884 + synonymous_variant Silent SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 36 8 63 0 ENST00000408966.2:c.54C>G p.Gly18= p.G18= ENST00000408966 NM_138464.2 18 ggC/ggG 0 +C9orf11 UCSF GRCh37 9 27294321 27294321 + synonymous_variant Silent SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 50 34 36 1 ENST00000380032.3:c.282A>G p.Leu94= p.L94= ENST00000380032 NM_020641.2 94 ctA/ctG 0 +CACNA2D4 UCSF GRCh37 12 2017100 2017100 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 27 5 32 0 ENST00000382722.5:c.590A>C p.Asn197Thr p.N197T ENST00000382722 NM_172364.4 197 aAc/aCc 0 +CAND1 UCSF GRCh37 12 67675701 67675701 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 109 23 102 0 ENST00000545606.1:c.80C>A p.Thr27Lys p.T27K ENST00000545606 NM_018448.3 27 aCa/aAa 0 +CARM1 UCSF GRCh37 19 11019790 11019790 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 52 9 52 0 ENST00000327064.4:c.465C>A p.Tyr155Ter p.Y155* ENST00000327064 NM_199141.1 155 taC/taA 0 +CBLL1 UCSF GRCh37 7 107399172 107399174 + inframe_deletion In_Frame_Del DEL CAC CAC - NOVEL P07_Rec Untested WXS Illumina HiSeq 10 0 ENST00000440859.3:c.1029_1031del p.Pro350del p.P350del ENST00000440859 NM_024814.2 342 gCACca/gca 0 +CBLL1 UCSF GRCh37 7 107399173 107399176 + protein_altering_variant In_Frame_Del DEL ACCA ACCA C NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000440859.3:c.1026_1029delinsC p.Pro350del p.P350del ENST00000440859 NM_024814.2 342 gcACCA/gcC 0 +CCDC103 UCSF GRCh37 17 42978399 42978399 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P07_Rec Untested WXS Illumina HiSeq 35 0 ENST00000417826.2:c.35del p.Leu12TrpfsTer45 p.L12Wfs*45 ENST00000417826 NM_001258399.1 11 gcT/gc 0 +CCDC27 UCSF GRCh37 1 3680383 3680383 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 16 8 41 0 ENST00000294600.2:c.1435C>A p.Gln479Lys p.Q479K ENST00000294600 NM_152492.2 479 Caa/Aaa 0 +CDK14 UCSF GRCh37 7 90546941 90546944 + frameshift_variant Frame_Shift_Del DEL GTCT GTCT - NOVEL P07_Rec Untested WXS Illumina HiSeq 31 0 ENST00000265741.3:c.678_681del p.Ser227ThrfsTer12 p.S227Tfs*12 ENST00000265741 NM_012395.2 225 gGTCTg/gg 0 +CELSR1 UCSF GRCh37 22 46790131 46790131 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 20 11 59 0 ENST00000262738.3:c.5872T>G p.Trp1958Gly p.W1958G ENST00000262738 NM_014246.1 1958 Tgg/Ggg 0 +CHRNA2 UCSF GRCh37 8 27327497 27327497 + splice_region_variant,synonymous_variant Splice_Region SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 32 12 41 1 ENST00000407991.1:c.75T>G p.Gly25= p.G25= ENST00000407991 NM_000742.3 25 ggT/ggG 0 +CLEC7A UCSF GRCh37 12 10279261 10279261 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 93 11 70 0 ENST00000304084.8:c.249C>A p.Tyr83Ter p.Y83* ENST00000304084 NM_197947.2 83 taC/taA 0 +CNTLN UCSF GRCh37 9 17486994 17486995 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P07_Rec Untested WXS Illumina HiSeq 26 0 ENST00000380647.3:c.4054dup p.Thr1352AsnfsTer4 p.T1352Nfs*4 ENST00000380647 1350 gaa/gaAa 0 +COL16A1 UCSF GRCh37 1 32118347 32118370 + frameshift_variant Frame_Shift_Del DEL TGCCTGGCTGGCCCATGGGACCCG TGCCTGGCTGGCCCATGGGACCCG C NOVEL P07_Rec 24 Untested WXS Illumina HiSeq 12 0 ENST00000373672.3:c.4697_4720delinsG p.Pro1566ArgfsTer6 p.P1566Rfs*6 ENST00000373672 NM_001856.3 1566 cCGGGTCCCATGGGCCAGCCAGGCAag/cGag 0 +COL4A4 UCSF GRCh37 2 227875211 227875211 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P07_Rec Untested WXS Illumina HiSeq 9 0 ENST00000396625.3:c.4340del p.Pro1447LeufsTer105 p.P1447Lfs*105 ENST00000396625 NM_000092.4 1447 cCt/ct 0 +CPNE3 UCSF GRCh37 8 87563330 87563330 + splice_donor_variant Splice_Site SNP T T G 1000g2011may_all_0.0465 P07_Rec Untested WXS Illumina HiSeq 38 26 103 1 ENST00000521271.1:c.1068+2T>G p.X356_splice ENST00000521271 NM_003909.3 0 +CRBN UCSF GRCh37 3 3215909 3215909 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 96 12 117 0 ENST00000231948.4:c.211A>G p.Thr71Ala p.T71A ENST00000231948 NM_016302.3 71 Act/Gct 0 +CSMD2 UCSF GRCh37 1 34554724 34554724 + stop_gained,NMD_transcript_variant Nonsense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 76 10 68 0 ENST00000241312.4:c.138C>A p.Tyr46Ter p.Y46* ENST00000241312 46 taC/taA 0 +CTNNA1 UCSF GRCh37 5 138260372 138260372 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 27 4 37 0 ENST00000302763.7:c.1720G>A p.Glu574Lys p.E574K ENST00000302763 NM_001903.2 574 Gaa/Aaa 0 +CTNNAL1 UCSF GRCh37 9 111718091 111718091 + stop_gained Nonsense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 105 15 105 0 ENST00000325551.4:c.1608C>A p.Tyr536Ter p.Y536* ENST00000325551 NM_003798.2 536 taC/taA 0 +CYBASC3 UCSF GRCh37 11 61120560 61120560 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 51 8 52 0 ENST00000426130.2:c.496C>G p.Arg166Gly p.R166G ENST00000426130 NM_001161454.1 166 Cgc/Ggc 0 +DCHS1 UCSF GRCh37 11 6643472 6643472 + synonymous_variant Silent SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 11 3 29 1 ENST00000299441.3:c.9435T>G p.Gly3145= p.G3145= ENST00000299441 NM_003737.2 3145 ggT/ggG 0 +DDHD2 UCSF GRCh37 8 38111154 38111154 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 175 37 131 0 ENST00000397166.2:c.1972C>T p.Arg658Cys p.R658C ENST00000397166 NM_015214.2 658 Cgc/Tgc 0 +DDX60L UCSF GRCh37 4 169315741 169315741 + stop_gained Nonsense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 173 32 138 0 ENST00000260184.7:c.3685C>T p.Arg1229Ter p.R1229* ENST00000260184 NM_001012967.1 1229 Cga/Tga 0 +DEFB126 UCSF GRCh37 20 126310 126311 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P07_Rec Untested WXS Illumina HiSeq 8 0 ENST00000382398.3:c.313_314del p.Thr105ProfsTer? p.T105Pfs*? ENST00000382398 NM_030931.3 105 ACc/c 0 +DIS3 UCSF GRCh37 13 73337743 73337743 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 74 13 132 1 ENST00000377767.4:c.1973A>G p.Glu658Gly p.E658G ENST00000377767 NM_014953.3 658 gAa/gGa 0 +DIXDC1 UCSF GRCh37 11 111853109 111853109 + frameshift_variant,splice_region_variant Frame_Shift_Ins INS T T CC NOVEL P07_Rec Untested WXS Illumina HiSeq 11 0 ENST00000440460.2:c.813delinsCC p.Gly272ArgfsTer44 p.G272Rfs*44 ENST00000440460 NM_001037954.3 271 ccT/ccCC 0 +DNAJA3 UCSF GRCh37 16 4500462 4500462 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 21 4 14 0 ENST00000262375.6:c.1303G>A p.Glu435Lys p.E435K ENST00000262375 NM_005147.5 435 Gag/Aag 0 +DNMT1 UCSF GRCh37 19 10270707 10270742 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACTGTTTTGGCGCGAGCCATTTTTTTCTCCGTTCTG ACTGTTTTGGCGCGAGCCATTTTTTTCTCCGTTCTG GTTGTTGTGGGGGGAGCCATTTTTTTCTCCGTTCT NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000340748.4:c.996-3_1028delinsAGAACGGAGAAAAAAATGGCTCCCCCCACAACAAC p.X332_splice ENST00000340748 0 +DOK6 UCSF GRCh37 18 67508602 67508602 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 93 12 101 0 ENST00000382713.5:c.979T>C p.Ser327Pro p.S327P ENST00000382713 NM_152721.5 327 Tcc/Ccc 0 +ERBB2IP UCSF GRCh37 5 65374262 65374262 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 74 19 100 0 ENST00000506030.1:c.4164C>A p.Tyr1388Ter p.Y1388* ENST00000506030 1388 taC/taA 0 +ERGIC3 UCSF GRCh37 20 34145203 34145203 + synonymous_variant Silent SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 69 9 89 0 ENST00000357394.4:c.1095A>G p.Gly365= p.G365= ENST00000357394 NM_198398.1 365 ggA/ggG 0 +ETFA UCSF GRCh37 15 76578040 76578040 + missense_variant Missense_Mutation SNP T T A NOVEL P07_Rec Untested WXS Illumina HiSeq 77 31 83 1 ENST00000557943.1:c.602A>T p.Asp201Val p.D201V ENST00000557943 NM_000126.3 201 gAc/gTc 0 +FAM108A1 UCSF GRCh37 19 1881408 1881408 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 60 9 40 0 ENST00000250974.9:c.158T>C p.Leu53Ser p.L53S ENST00000250974 NM_031213.3 53 tTg/tCg 0 +FAM58BP UCSF GRCh37 1 200183278 200183278 + non_coding_transcript_exon_variant RNA SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0088 P07_Rec Untested WXS Illumina HiSeq 88 17 59 0 ENST00000424019.1:n.623C>T *208* ENST00000424019 0 +FCER1A UCSF GRCh37 1 159275786 159275786 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 72 12 115 0 ENST00000368115.1:c.340C>G p.Leu114Val p.L114V ENST00000368115 NM_002001.3 114 Ctc/Gtc 0 +FMN1 UCSF GRCh37 15 33261341 33261341 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 61 37 70 1 ENST00000334528.9:c.1892T>C p.Leu631Pro p.L631P ENST00000334528 NM_001103184.3 631 cTc/cCc 0 +GFM1 UCSF GRCh37 3 158384100 158384100 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 41 12 32 0 ENST00000486715.1:c.1526A>G p.Glu509Gly p.E509G ENST00000486715 NM_024996.5 509 gAa/gGa 0 +GGTLC2 UCSF GRCh37 22 22988917 22988917 + synonymous_variant Silent SNP T T C 1000g2011may_all_0.0094,snp132_rs71316772 P07_Rec Untested WXS Illumina HiSeq 22 5 16 0 ENST00000480559.1:c.102T>C p.Asp34= p.D34= ENST00000480559 NM_199127.2 34 gaT/gaC 0 +GIF UCSF GRCh37 11 59610508 59610508 + synonymous_variant Silent SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 56 13 67 1 ENST00000257248.2:c.363A>C p.Ala121= p.A121= ENST00000257248 NM_005142.2 121 gcA/gcC 0 +GIGYF1 UCSF GRCh37 7 100285167 100285167 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec somatic WXS Sanger Illumina HiSeq 68 13 72 0 ENST00000275732.5:c.334G>C p.Ala112Pro p.A112P ENST00000275732 NM_022574.4 112 Gct/Cct 0 +GOLGB1 UCSF GRCh37 3 121435721 121435721 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 204 37 166 0 ENST00000393667.3:c.1151C>G p.Ser384Cys p.S384C ENST00000393667 NM_001256486.1 384 tCt/tGt 0 +GORASP2 UCSF GRCh37 2 171806771 171806771 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 70 17 58 0 ENST00000234160.4:c.406A>G p.Ile136Val p.I136V ENST00000234160 NM_015530.4 136 Ata/Gta 0 +GPR26 UCSF GRCh37 10 125447449 125447449 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 45 16 76 0 ENST00000284674.1:c.787G>A p.Val263Met p.V263M ENST00000284674 NM_153442.3 263 Gtg/Atg 0 +GRXCR1 UCSF GRCh37 4 43032401 43032401 + synonymous_variant Silent SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 118 53 120 0 ENST00000399770.2:c.717T>C p.Cys239= p.C239= ENST00000399770 NM_001080476.2 239 tgT/tgC 0 +HDLBP UCSF GRCh37 2 242179463 242179463 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P07_Rec Untested WXS Illumina HiSeq 13 0 ENST00000391975.1:c.2244del p.Ile750PhefsTer24 p.I750Ffs*24 ENST00000391975 NM_203346.3 748 ggC/gg 0 +HEATR2 UCSF GRCh37 7 796564 796564 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 21 14 42 0 ENST00000297440.6:c.1403T>C p.Leu468Pro p.L468P ENST00000297440 NM_017802.3 468 cTc/cCc 0 +HLA-DQB1 UCSF GRCh37 6 32629150 32629150 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 21 47 49 0 ENST00000374943.4:c.746T>C p.Leu249Pro p.L249P ENST00000374943 NM_001243961.1 249 cTt/cCt 0 +HLX UCSF GRCh37 1 221054610 221054610 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 129 23 98 0 ENST00000366903.6:c.667T>C p.Phe223Leu p.F223L ENST00000366903 NM_021958.3 223 Ttc/Ctc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 83 51 98 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +ILK UCSF GRCh37 11 6629291 6629291 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 78 13 94 0 ENST00000396751.2:c.105C>T p.Phe35= p.F35= ENST00000396751 NM_001014795.2 35 ttC/ttT 0 +IPO5 UCSF GRCh37 13 98637679 98637679 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 110 16 118 0 ENST00000261574.5:c.230G>A p.Arg77Lys p.R77K ENST00000261574 NM_002271.4 77 aGa/aAa 0 +IRX6 UCSF GRCh37 16 55361522 55361522 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 34 28 70 0 ENST00000290552.7:c.438C>T p.Gly146= p.G146= ENST00000290552 NM_024335.2 146 ggC/ggT 0 +KIAA0564 UCSF GRCh37 13 42164786 42164786 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 105 12 61 0 ENST00000379310.3:c.5102T>G p.Leu1701Arg p.L1701R ENST00000379310 NM_015058.1 1701 cTg/cGg 0 +KIAA1267 UCSF GRCh37 17 44144000 44144002 + inframe_deletion In_Frame_Del DEL GAT GAT - NOVEL P07_Rec Untested WXS Illumina HiSeq 30 0 ENST00000262419.6:c.1749_1751del p.Ser584del p.S584del ENST00000262419 NM_001193466.1 583 tcATCt/tct 0 +KIAA1462 UCSF GRCh37 10 30316881 30316881 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 75 56 69 0 ENST00000375377.1:c.2196G>A p.Thr732= p.T732= ENST00000375377 NM_020848.2 732 acG/acA 0 +KRBA1 UCSF GRCh37 7 149430470 149430470 + synonymous_variant Silent SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 98 42 68 0 ENST00000255992.10:c.2424C>T p.Ala808= p.A808= ENST00000255992 NM_032534.2 808 gcC/gcT 0 +KRT7 UCSF GRCh37 12 52642412 52642412 + synonymous_variant Silent SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 24 4 44 0 ENST00000331817.5:c.1278T>G p.Gly426= p.G426= ENST00000331817 NM_005556.3 426 ggT/ggG 0 +L3MBTL3 UCSF GRCh37 6 130387509 130387509 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 95 12 129 0 ENST00000529410.1:c.876C>A p.Tyr292Ter p.Y292* ENST00000529410 292 taC/taA 0 +LAMA2 UCSF GRCh37 6 129824352 129824352 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 96 64 106 0 ENST00000421865.2:c.8474T>C p.Phe2825Ser p.F2825S ENST00000421865 NM_001079823.1 2825 tTc/tCc 0 +LAMB4 UCSF GRCh37 7 107703235 107703235 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 67 10 64 0 ENST00000388781.3:c.3266G>T p.Ser1089Ile p.S1089I ENST00000388781 NM_007356.2 1089 aGt/aTt 0 +LANCL3 UCSF GRCh37 X 37518731 37518731 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 27 5 35 0 ENST00000378619.3:c.714G>T p.Leu238Phe p.L238F ENST00000378619 NM_001170331.1 238 ttG/ttT 0 +LRP2 UCSF GRCh37 2 169993907 169993907 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 91 54 95 0 ENST00000263816.3:c.13615A>G p.Ile4539Val p.I4539V ENST00000263816 NM_004525.2 4539 Atc/Gtc 0 +MAK16 UCSF GRCh37 8 33346526 33346526 + stop_gained Nonsense_Mutation SNP T T A NOVEL P07_Rec Untested WXS Illumina HiSeq 196 37 158 0 ENST00000360128.6:c.261T>A p.Tyr87Ter p.Y87* ENST00000360128 NM_032509.3 87 taT/taA 0 +MAPK8IP3 UCSF GRCh37 16 1815990 1815990 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 15 16 36 0 ENST00000250894.4:c.2473G>A p.Glu825Lys p.E825K ENST00000250894 NM_015133.3 825 Gag/Aag 0 +MEF2C UCSF GRCh37 5 88025121 88025121 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 109 13 64 0 ENST00000340208.5:c.908C>A p.Thr303Asn p.T303N ENST00000340208 NM_001193347.1 303 aCc/aAc 0 +MLL3 UCSF GRCh37 7 151874148 151874149 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000262189.6:c.8390dup p.Glu2798GlyfsTer11 p.E2798Gfs*11 ENST00000262189 NM_170606.2 2797 aag/aAag 0 +MPP4 UCSF GRCh37 2 202545740 202545740 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 151 18 117 0 ENST00000409474.3:c.750G>A p.Met250Ile p.M250I ENST00000409474 NM_033066.2 250 atG/atA 0 +MRPL47 UCSF GRCh37 3 179310526 179310526 + missense_variant,splice_region_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 52 16 100 0 ENST00000476781.1:c.535C>G p.His179Asp p.H179D ENST00000476781 NM_020409.2 179 Cac/Gac 0 +MTHFR UCSF GRCh37 1 11854002 11854002 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 56 12 55 0 ENST00000376592.1:c.1492G>A p.Val498Met p.V498M ENST00000376592 498 Gtg/Atg 0 +NARS2 UCSF GRCh37 11 78277317 78277317 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 90 23 135 2 ENST00000281038.5:c.374A>G p.Asp125Gly p.D125G ENST00000281038 NM_001243251.1 125 gAt/gGt 0 +NLGN4Y UCSF GRCh37 Y 16942197 16942197 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 39 9 74 0 ENST00000355905.2:c.1399A>C p.Thr467Pro p.T467P ENST00000355905 NM_014893.4 467 Acc/Ccc 0 +NLRP3 UCSF GRCh37 1 247587244 247587244 + missense_variant Missense_Mutation SNP C C T NOVEL P07_Rec Untested WXS Illumina HiSeq 52 7 55 0 ENST00000336119.3:c.499C>T p.Arg167Cys p.R167C ENST00000336119 NM_001127462.2 167 Cgc/Tgc 0 +NOTCH1 UCSF GRCh37 9 139391036 139391036 + synonymous_variant Silent SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 43 8 76 0 ENST00000277541.6:c.7155G>C p.Val2385= p.V2385= ENST00000277541 NM_017617.3 2385 gtG/gtC 0 +NUDT10 UCSF GRCh37 X 51076024 51076024 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.00397,1000g2011may_all_0.0126,snp132_rs2801626 P07_Rec Untested WXS Illumina HiSeq 53 6 33 0 ENST00000376006.3:c.207G>A p.Glu69= p.E69= ENST00000376006 NM_153183.2 69 gaG/gaA 0 +OCA2 UCSF GRCh37 15 28231781 28231781 + missense_variant Missense_Mutation SNP T T A NOVEL P07_Rec Untested WXS Illumina HiSeq 146 18 160 0 ENST00000354638.3:c.1191A>T p.Leu397Phe p.L397F ENST00000354638 NM_000275.2 397 ttA/ttT 0 +OR4A15 UCSF GRCh37 11 55135516 55135516 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 212 26 196 0 ENST00000314706.3:c.157A>G p.Lys53Glu p.K53E ENST00000314706 NM_001005275.1 53 Aag/Gag 0 +PCDHB14 UCSF GRCh37 5 140604999 140604999 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 36 11 50 0 ENST00000239449.4:c.1922T>G p.Val641Gly p.V641G ENST00000239449 NM_018934.2 641 gTg/gGg 0 +PCNX UCSF GRCh37 14 71568927 71568927 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P07_Rec Untested WXS Illumina HiSeq 17 0 ENST00000304743.2:c.5812del p.Val1938SerfsTer4 p.V1938Sfs*4 ENST00000304743 NM_014982.2 1937 aGg/ag 0 +PCNXL3 UCSF GRCh37 11 65402768 65402768 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 10 4 16 1 ENST00000355703.3:c.5033T>G p.Val1678Gly p.V1678G ENST00000355703 NM_032223.2 1678 gTc/gGc 0 +PGC UCSF GRCh37 6 41715059 41715059 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 41 7 61 1 ENST00000373025.3:c.14T>G p.Val5Gly p.V5G ENST00000373025 NM_002630.3 5 gTg/gGg 0 +PNLIP UCSF GRCh37 10 118307928 118307928 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 199 30 154 0 ENST00000369221.2:c.258A>C p.Lys86Asn p.K86N ENST00000369221 NM_000936.2 86 aaA/aaC 0 +PNOC UCSF GRCh37 8 28196684 28196684 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 34 10 77 0 ENST00000301908.3:c.254A>C p.Tyr85Ser p.Y85S ENST00000301908 NM_006228.3 85 tAc/tCc 0 +PRKG1 UCSF GRCh37 10 53564389 53564389 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 82 12 97 0 ENST00000373980.4:c.637C>G p.Gln213Glu p.Q213E ENST00000373980 NM_006258.3 213 Caa/Gaa 0 +PRSS1 UCSF GRCh37 7 142460412 142460431 + coding_sequence_variant,intron_variant In_Frame_Del DEL ATGTCAGGTGATTTGACCAA ATGTCAGGTGATTTGACCAA CTGCCAGGTGATTTGAC NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000311737.7:c.585_591+13delinsCTGCCAGGTGATTTGAC *195* ENST00000311737 NM_002769.4 195 0 +PRSS48 UCSF GRCh37 4 152201017 152201018 + frameshift_variant Frame_Shift_Ins INS - - GGCAG NOVEL P07_Rec Untested WXS Illumina HiSeq 9 0 ENST00000455694.2:c.123_124insGCAGG p.Gln42AlafsTer23 p.Q42Afs*23 ENST00000455694 NM_183375.2 41 tgg/tgGGCAGg 0 +PSMD10 UCSF GRCh37 X 107331324 107331324 + synonymous_variant Silent SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 35 11 63 0 ENST00000217958.3:c.219T>G p.Gly73= p.G73= ENST00000217958 NM_170750.2 73 ggT/ggG 0 +RNF133 UCSF GRCh37 7 122338115 122338115 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 289 35 165 0 ENST00000340112.2:c.858G>C p.Trp286Cys p.W286C ENST00000340112 NM_139175.1 286 tgG/tgC 0 +SDF2 UCSF GRCh37 17 26982450 26982450 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P07_Rec Untested WXS Illumina HiSeq 21 0 ENST00000247020.4:c.203del p.Ser68IlefsTer27 p.S68Ifs*27 ENST00000247020 NM_006923.3 68 aGt/at 0 +SEMA3G UCSF GRCh37 3 52474094 52474094 + synonymous_variant Silent SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 52 8 42 0 ENST00000231721.2:c.1164A>G p.Ala388= p.A388= ENST00000231721 NM_020163.1 388 gcA/gcG 0 +SGIP1 UCSF GRCh37 1 67147609 67147609 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 179 34 136 0 ENST00000371037.4:c.872T>C p.Leu291Ser p.L291S ENST00000371037 NM_032291.2 291 tTg/tCg 0 +SIGLEC12 UCSF GRCh37 19 52001516 52001516 + synonymous_variant Silent SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 52 10 82 1 ENST00000291707.3:c.1161G>C p.Ser387= p.S387= ENST00000291707 NM_053003.2 387 tcG/tcC 0 +SLC15A3 UCSF GRCh37 11 60714292 60714292 + missense_variant,splice_region_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 54 9 74 0 ENST00000227880.3:c.560T>G p.Val187Gly p.V187G ENST00000227880 NM_016582.2 187 gTg/gGg 0 +SLC1A5 UCSF GRCh37 19 47281995 47281995 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 45 14 46 0 ENST00000542575.2:c.995A>C p.Asn332Thr p.N332T ENST00000542575 NM_005628.2 332 aAc/aCc 0 +SLC22A15 UCSF GRCh37 1 116562262 116562262 + synonymous_variant Silent SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 252 35 192 0 ENST00000369503.4:c.360T>C p.Ser120= p.S120= ENST00000369503 NM_018420.2 120 agT/agC 0 +SLC24A1 UCSF GRCh37 15 65918177 65918179 + inframe_deletion In_Frame_Del DEL CTG CTG - 1000g2010nov_all P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000261892.6:c.1771_1773delCTG p.Leu591del p.L591del ENST00000261892 NM_004727.2 587 CTG/- 0 +SLC25A11 UCSF GRCh37 17 4841768 4841805 + splice_donor_variant,intron_variant Splice_Site INS AGACCTCACAGCCCCCAAGTCTCCAGCCCCTCCACTCA AGACCTCACAGCCCCCAAGTCTCCAGCCCCTCCACTCA CACCCCCCCCCCCCCCAACCCCCCCAGCCCCTCCCCCCC NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000225665.7:c.546+2_546+39delinsGGGGGGGAGGGGCTGGGGGGGTTGGGGGGGGGGGGGGTG p.X182_splice ENST00000225665 NM_001165417.1 0 +SLC39A10 UCSF GRCh37 2 196544942 196544942 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000409086.3:c.183del p.Lys61AsnfsTer26 p.K61Nfs*26 ENST00000409086 NM_001127257.1 59 gAa/ga 0 +SLC3A1 UCSF GRCh37 2 44539860 44539860 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 83 15 77 0 ENST00000260649.6:c.1468G>T p.Val490Leu p.V490L ENST00000260649 NM_000341.3 490 Gta/Tta 0 +SLC41A1 UCSF GRCh37 1 205760812 205760812 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 42 8 57 0 ENST00000367137.3:c.1391T>G p.Val464Gly p.V464G ENST00000367137 NM_173854.4 464 gTg/gGg 0 +SLC4A9 UCSF GRCh37 5 139743677 139743677 + synonymous_variant Silent SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 34 8 51 2 ENST00000230993.6:c.1365A>G p.Gly455= p.G455= ENST00000230993 NM_001258428.1 455 ggA/ggG 0 +SLC5A10 UCSF GRCh37 17 18923739 18923739 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 38 25 65 2 ENST00000395647.2:c.1834G>C p.Ala612Pro p.A612P ENST00000395647 NM_152351.4 612 Gcc/Ccc 0 +SLC5A8 UCSF GRCh37 12 101588918 101588918 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0014 P07_Rec Untested WXS Illumina HiSeq 84 12 60 0 ENST00000536262.2:c.492C>T p.Gly164= p.G164= ENST00000536262 NM_145913.3 164 ggC/ggT 0 +SLC7A4 UCSF GRCh37 22 21384142 21384142 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 32 27 54 0 ENST00000382932.2:c.1481G>T p.Cys494Phe p.C494F ENST00000382932 NM_004173.2 494 tGc/tTc 0 +SMARCA4 UCSF GRCh37 19 11096909 11096909 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec somatic WXS Sanger Illumina HiSeq 59 10 61 0 ENST00000344626.4:c.400G>C p.Val134Leu p.V134L ENST00000344626 NM_003072.3 134 Gtt/Ctt 0 +SPATC1 UCSF GRCh37 8 145086738 145086738 + missense_variant Missense_Mutation SNP C C G NOVEL P07_Rec Untested WXS Illumina HiSeq 13 12 31 0 ENST00000377470.3:c.55C>G p.Arg19Gly p.R19G ENST00000377470 NM_198572.2 19 Cgg/Ggg 0 +SRCRB4D UCSF GRCh37 7 76033635 76033635 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 27 16 56 0 ENST00000275560.3:c.122T>C p.Leu41Pro p.L41P ENST00000275560 NM_080744.1 41 cTc/cCc 0 +STOML2 UCSF GRCh37 9 35102804 35102804 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 53 8 75 0 ENST00000356493.5:c.62C>T p.Ser21Phe p.S21F ENST00000356493 NM_013442.1 21 tCt/tTt 0 +SUSD2 UCSF GRCh37 22 24583952 24583952 + synonymous_variant Silent SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 35 8 40 0 ENST00000358321.3:c.2190A>C p.Pro730= p.P730= ENST00000358321 NM_019601.3 730 ccA/ccC 0 +SUSD3 UCSF GRCh37 9 95838089 95838089 + missense_variant Missense_Mutation SNP C C A 1000g2011may_all_0.0392 P07_Rec Untested WXS Illumina HiSeq 51 11 43 0 ENST00000375472.3:c.112C>A p.Pro38Thr p.P38T ENST00000375472 NM_145006.2 38 Ccc/Acc 0 +T UCSF GRCh37 6 166576023 166576023 + synonymous_variant Silent SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 52 12 50 0 ENST00000296946.2:c.816C>T p.Ser272= p.S272= ENST00000296946 NM_003181.3 272 tcC/tcT 0 +TCEB3C UCSF GRCh37 18 44554967 44554967 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 109 13 307 0 ENST00000330682.2:c.1247A>C p.Tyr416Ser p.Y416S ENST00000330682 NM_145653.3 416 tAc/tCc 0 +TCERG1L UCSF GRCh37 10 132915117 132915117 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 54 10 84 0 ENST00000368642.4:c.1340T>C p.Leu447Pro p.L447P ENST00000368642 NM_174937.3 447 cTc/cCc 0 +TMEM144 UCSF GRCh37 4 159158783 159158783 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 58 14 88 0 ENST00000296529.6:c.670G>A p.Ala224Thr p.A224T ENST00000296529 NM_018342.4 224 Gca/Aca 0 +TMEM155 UCSF GRCh37 4 122681471 122681471 + missense_variant Missense_Mutation SNP G G T NOVEL P07_Rec Untested WXS Illumina HiSeq 59 7 85 0 ENST00000337677.5:c.371C>A p.Thr124Asn p.T124N ENST00000337677 NM_152399.2 124 aCt/aAt 0 +TMEM161A UCSF GRCh37 19 19232150 19232150 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 24 9 48 1 ENST00000162044.9:c.881A>C p.His294Pro p.H294P ENST00000162044 NM_017814.2 294 cAc/cCc 0 +TMEM175 UCSF GRCh37 4 949253 949253 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 35 4 35 0 ENST00000264771.4:c.688T>G p.Cys230Gly p.C230G ENST00000264771 NM_032326.2 230 Tgc/Ggc 0 +TMEM177 UCSF GRCh37 2 120438443 120438443 + missense_variant Missense_Mutation SNP T T C NOVEL P07_Rec Untested WXS Illumina HiSeq 36 6 81 0 ENST00000424086.1:c.14T>C p.Leu5Pro p.L5P ENST00000424086 NM_001105198.1 5 cTg/cCg 0 +TMPRSS9 UCSF GRCh37 19 2422016 2422016 + synonymous_variant Silent SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 120 14 109 0 ENST00000332578.3:c.2217C>A p.Pro739= p.P739= ENST00000332578 NM_182973.1 739 ccC/ccA 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 17 80 72 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TPSD1 UCSF GRCh37 16 1307050 1307050 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.019 P07_Rec Untested WXS Illumina HiSeq 34 5 32 1 ENST00000211076.3:c.507C>T p.Asp169= p.D169= ENST00000211076 NM_012217.2 169 gaC/gaT 0 +TPX2 UCSF GRCh37 20 30385297 30385297 + missense_variant Missense_Mutation SNP A A G NOVEL P07_Rec Untested WXS Illumina HiSeq 134 59 157 0 ENST00000300403.6:c.1924A>G p.Lys642Glu p.K642E ENST00000300403 NM_012112.4 642 Aaa/Gaa 0 +TRIM56 UCSF GRCh37 7 100732823 100732823 + missense_variant Missense_Mutation SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 59 14 59 1 ENST00000306085.6:c.2230A>C p.Thr744Pro p.T744P ENST00000306085 NM_030961.1 744 Acc/Ccc 0 +TUBB6 UCSF GRCh37 18 12325728 12325728 + missense_variant Missense_Mutation SNP G G C NOVEL P07_Rec Untested WXS Illumina HiSeq 87 57 105 0 ENST00000317702.5:c.940G>C p.Ala314Pro p.A314P ENST00000317702 314 Gcc/Ccc 0 +TUBG2 UCSF GRCh37 17 40815072 40815072 + splice_donor_variant Splice_Site SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 63 14 89 0 ENST00000251412.7:c.479+2C>A p.X160_splice ENST00000251412 NM_016437.2 0 +UGT1A3 UCSF GRCh37 2 234638624 234638624 + synonymous_variant Silent SNP G G A NOVEL P07_Rec Untested WXS Illumina HiSeq 81 10 165 0 ENST00000482026.1:c.852G>A p.Arg284= p.R284= ENST00000482026 284 agG/agA 0 +UPK3BL UCSF GRCh37 7 102279621 102279621 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.034,1000g2011may_all_0.1195,snp132_rs56365279 P07_Rec Untested WXS Illumina HiSeq 10 5 10 0 ENST00000340457.8:c.511G>A p.Glu171Lys p.E171K ENST00000340457 NM_001114403.2 171 Gaa/Aaa 0 +USP21 UCSF GRCh37 1 161132755 161132755 + missense_variant Missense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 115 13 95 0 ENST00000368002.3:c.940C>A p.His314Asn p.H314N ENST00000368002 NM_001014443.2 314 Cac/Aac 0 +VAX1 UCSF GRCh37 10 118893633 118893633 + synonymous_variant Silent SNP A A C NOVEL P07_Rec Untested WXS Illumina HiSeq 10 4 20 0 ENST00000369206.5:c.891T>G p.Gly297= p.G297= ENST00000369206 NM_001112704.1 297 ggT/ggG 0 +VGF UCSF GRCh37 7 100806737 100806737 + missense_variant Missense_Mutation SNP T T G NOVEL P07_Rec Untested WXS Illumina HiSeq 24 9 22 0 ENST00000249330.2:c.1388A>C p.His463Pro p.H463P ENST00000249330 NM_003378.3 463 cAc/cCc 0 +ZCCHC16 UCSF GRCh37 X 111698509 111698513 + frameshift_variant Frame_Shift_Del DEL GAAAA GAAAA - NOVEL P07_Rec Untested WXS Illumina HiSeq 6 0 ENST00000340433.2:c.554_558del p.Glu185GlyfsTer4 p.E185Gfs*4 ENST00000340433 NM_001004308.2 185 GAAAAg/g 0 +ZNRF3 UCSF GRCh37 22 29445795 29445795 + stop_gained Nonsense_Mutation SNP C C A NOVEL P07_Rec Untested WXS Illumina HiSeq 30 7 56 0 ENST00000544604.2:c.1626C>A p.Tyr542Ter p.Y542* ENST00000544604 NM_001206998.1 542 taC/taA 0 +ACR UCSF GRCh37 22 51178337 51178337 + missense_variant Missense_Mutation SNP T T G NOVEL P08_Pri Untested WXS Illumina HiSeq 48 34 91 0 ENST00000216139.5:c.497T>G p.Phe166Cys p.F166C ENST00000216139 NM_001097.2 166 tTt/tGt 0 +ATR UCSF GRCh37 3 142176497 142176497 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P08_Pri Untested WXS Illumina HiSeq 25 0 ENST00000350721.4:c.7604del p.Ala2535AspfsTer6 p.A2535Dfs*6 ENST00000350721 NM_001184.3 2535 gCa/ga 0 +ATRX UCSF GRCh37 X 76938089 76938090 + frameshift_variant Frame_Shift_Del DEL TC TC - NOVEL P08_Pri Untested WXS Illumina HiSeq 26 0 ENST00000373344.5:c.2658_2659del p.Glu886AspfsTer10 p.E886Dfs*10 ENST00000373344 NM_000489.3 886 gaGAct/gact 0 +BMP10 UCSF GRCh37 2 69092971 69092971 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 62 13 141 0 ENST00000295379.1:c.1067G>A p.Cys356Tyr p.C356Y ENST00000295379 NM_014482.1 356 tGt/tAt 0 +CCDC91 UCSF GRCh37 12 28603099 28603099 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Pri Untested WXS Illumina HiSeq 74 15 153 0 ENST00000545336.1:c.768G>T p.Gln256His p.Q256H ENST00000545336 256 caG/caT 0 +CNOT6 UCSF GRCh37 5 179977041 179977041 + missense_variant Missense_Mutation SNP A A C NOVEL P08_Pri Untested WXS Illumina HiSeq 61 7 152 0 ENST00000393356.1:c.223A>C p.Asn75His p.N75H ENST00000393356 75 Aat/Cat 0 +COG4 UCSF GRCh37 16 70551568 70551568 + synonymous_variant Silent SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 58 8 131 0 ENST00000323786.5:c.330G>A p.Glu110= p.E110= ENST00000323786 NM_015386.2 110 gaG/gaA 0 +CPNE8 UCSF GRCh37 12 39047732 39047732 + synonymous_variant Silent SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 43 23 95 0 ENST00000331366.5:c.1647G>A p.Ala549= p.A549= ENST00000331366 NM_153634.2 549 gcG/gcA 0 +DDX60 UCSF GRCh37 4 169194524 169194524 + missense_variant Missense_Mutation SNP G G C NOVEL P08_Pri Untested WXS Illumina HiSeq 61 12 173 0 ENST00000393743.3:c.2480C>G p.Thr827Ser p.T827S ENST00000393743 NM_017631.5 827 aCt/aGt 0 +FANCF UCSF GRCh37 11 22646911 22646911 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Pri Untested WXS Illumina HiSeq 42 19 170 0 ENST00000327470.3:c.446A>G p.Asn149Ser p.N149S ENST00000327470 NM_022725.3 149 aAt/aGt 0 +GGT7 UCSF GRCh37 20 33440238 33440238 + stop_gained Nonsense_Mutation SNP G G A NOVEL P08_Pri Untested WXS Illumina HiSeq 34 15 92 0 ENST00000336431.5:c.1423C>T p.Gln475Ter p.Q475* ENST00000336431 NM_178026.2 475 Cag/Tag 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 65 20 143 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +MSTN UCSF GRCh37 2 190925003 190925003 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Pri Untested WXS Illumina HiSeq 77 38 204 0 ENST00000260950.4:c.532A>G p.Lys178Glu p.K178E ENST00000260950 NM_005259.2 178 Aaa/Gaa 0 +MYF5 UCSF GRCh37 12 81110945 81110945 + stop_gained Nonsense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 21 6 46 0 ENST00000228644.3:c.103C>T p.Arg35Ter p.R35* ENST00000228644 NM_005593.2 35 Cga/Tga 0 +NBAS UCSF GRCh37 2 15679476 15679476 + synonymous_variant Silent SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 68 15 152 0 ENST00000281513.5:c.384G>A p.Pro128= p.P128= ENST00000281513 NM_015909.3 128 ccG/ccA 0 +PIK3C2B UCSF GRCh37 1 204400818 204400818 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P08_Pri Untested WXS Illumina HiSeq 6 0 ENST00000367187.3:c.4259del p.Phe1420SerfsTer14 p.F1420Sfs*14 ENST00000367187 NM_002646.3 1420 tTc/tc 0 +PRMT5 UCSF GRCh37 14 23396859 23396859 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Pri somatic WXS Sanger Illumina HiSeq 52 20 110 0 ENST00000324366.8:c.326A>G p.Gln109Arg p.Q109R ENST00000324366 NM_006109.3 109 cAg/cGg 0 +RP1 UCSF GRCh37 8 55538949 55538949 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 92 18 144 0 ENST00000220676.1:c.2507C>T p.Pro836Leu p.P836L ENST00000220676 NM_006269.1 836 cCg/cTg 0 +TBCE UCSF GRCh37 1 235600735 235600735 + synonymous_variant Silent SNP G G A NOVEL P08_Pri Untested WXS Illumina HiSeq 34 23 97 0 ENST00000366601.3:c.1062G>A p.Ala354= p.A354= ENST00000366601 354 gcG/gcA 0 +TP53 UCSF GRCh37 17 7577099 7577099 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Pri Untested WXS Illumina HiSeq 10 20 65 0 ENST00000269305.4:c.839G>A p.Arg280Lys p.R280K ENST00000269305 NM_001126112.2 280 aGa/aAa 0 +USH2A UCSF GRCh37 1 215901628 215901628 + missense_variant Missense_Mutation SNP A A G NOVEL P08_Pri Untested WXS Illumina HiSeq 55 19 179 0 ENST00000307340.3:c.11810T>C p.Leu3937Pro p.L3937P ENST00000307340 NM_206933.2 3937 cTc/cCc 0 +USH2A UCSF GRCh37 1 216363700 216363700 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Pri Untested WXS Illumina HiSeq 80 25 185 0 ENST00000307340.3:c.4261A>G p.Thr1421Ala p.T1421A ENST00000307340 NM_206933.2 1421 Act/Gct 0 +WDR63 UCSF GRCh37 1 85583512 85583512 + missense_variant Missense_Mutation SNP C C G NOVEL P08_Pri Untested WXS Illumina HiSeq 64 33 194 0 ENST00000294664.6:c.1887C>G p.Asp629Glu p.D629E ENST00000294664 NM_145172.3 629 gaC/gaG 0 +ZBTB20 UCSF GRCh37 3 114070562 114070564 + inframe_deletion In_Frame_Del DEL CAC CAC - NOVEL P08_Pri Untested WXS Illumina HiSeq 10 0 ENST00000474710.1:c.361_363del p.Val121del p.V121del ENST00000474710 NM_001164342.1 121 GTG/- 0 +ACR UCSF GRCh37 22 51178337 51178337 + missense_variant Missense_Mutation SNP T T G NOVEL P08_Rec Untested WXS Illumina HiSeq 61 46 91 0 ENST00000216139.5:c.497T>G p.Phe166Cys p.F166C ENST00000216139 NM_001097.2 166 tTt/tGt 0 +APOH UCSF GRCh37 17 64210715 64210718 + frameshift_variant Frame_Shift_Del DEL CTCT CTCT - NOVEL P08_Rec Untested WXS Illumina HiSeq 14 0 ENST00000205948.6:c.835_838del p.Arg279Ter p.R279* ENST00000205948 NM_000042.2 279 AGAGta/ta 0 +ATR UCSF GRCh37 3 142176497 142176497 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P08_Rec Untested WXS Illumina HiSeq 48 0 ENST00000350721.4:c.7604del p.Ala2535AspfsTer6 p.A2535Dfs*6 ENST00000350721 NM_001184.3 2535 gCa/ga 0 +ATRX UCSF GRCh37 X 76938089 76938090 + frameshift_variant Frame_Shift_Del DEL TC TC - NOVEL P08_Rec Untested WXS Illumina HiSeq 72 0 ENST00000373344.5:c.2658_2659del p.Glu886AspfsTer10 p.E886Dfs*10 ENST00000373344 NM_000489.3 886 gaGAct/gact 0 +CARM1 UCSF GRCh37 19 11024651 11024651 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 26 21 46 0 ENST00000327064.4:c.768G>A p.Ser256= p.S256= ENST00000327064 NM_199141.1 256 tcG/tcA 0 +CASP5 UCSF GRCh37 11 104869682 104869682 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 71 50 149 0 ENST00000393141.2:c.1065C>T p.Asn355= p.N355= ENST00000393141 NM_004347.3 355 aaC/aaT 0 +CENPQ UCSF GRCh37 6 49438702 49438702 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P08_Rec Untested WXS Illumina HiSeq 6 0 ENST00000335783.3:c.125del p.Asn42IlefsTer5 p.N42Ifs*5 ENST00000335783 NM_018132.3 40 Aaa/aa 0 +CNOT6 UCSF GRCh37 5 179977041 179977041 + missense_variant Missense_Mutation SNP A A C NOVEL P08_Rec Untested WXS Illumina HiSeq 24 76 152 0 ENST00000393356.1:c.223A>C p.Asn75His p.N75H ENST00000393356 75 Aat/Cat 0 +COL12A1 UCSF GRCh37 6 75829108 75829108 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 88 50 196 0 ENST00000322507.8:c.7168G>A p.Ala2390Thr p.A2390T ENST00000322507 NM_004370.5 2390 Gcc/Acc 0 +COL27A1 UCSF GRCh37 9 117002729 117002729 + stop_gained Nonsense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 60 44 101 0 ENST00000356083.3:c.2797C>T p.Arg933Ter p.R933* ENST00000356083 NM_032888.2 933 Cga/Tga 0 +CPNE8 UCSF GRCh37 12 39047732 39047732 + synonymous_variant Silent SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 55 33 95 0 ENST00000331366.5:c.1647G>A p.Ala549= p.A549= ENST00000331366 NM_153634.2 549 gcG/gcA 0 +CSPG4 UCSF GRCh37 15 75982257 75982257 + synonymous_variant Silent SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 30 4 31 1 ENST00000308508.5:c.1149G>A p.Glu383= p.E383= ENST00000308508 NM_001897.4 383 gaG/gaA 0 +CUL9 UCSF GRCh37 6 43190347 43190347 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Rec Untested WXS Illumina HiSeq 16 11 40 0 ENST00000252050.4:c.7000G>T p.Asp2334Tyr p.D2334Y ENST00000252050 NM_015089.2 2334 Gat/Tat 0 +CYSLTR1 UCSF GRCh37 X 77528900 77528900 + missense_variant Missense_Mutation SNP G G C NOVEL P08_Rec Untested WXS Illumina HiSeq 19 44 63 0 ENST00000373304.3:c.344C>G p.Thr115Arg p.T115R ENST00000373304 NM_001282188.1 115 aCa/aGa 0 +DDX60 UCSF GRCh37 4 169194524 169194524 + missense_variant Missense_Mutation SNP G G C NOVEL P08_Rec Untested WXS Illumina HiSeq 13 53 173 0 ENST00000393743.3:c.2480C>G p.Thr827Ser p.T827S ENST00000393743 NM_017631.5 827 aCt/aGt 0 +DTNA UCSF GRCh37 18 32407604 32407604 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 14 119 184 0 ENST00000598334.1:c.1049C>T p.Ser350Phe p.S350F ENST00000598334 NM_001198938.1 350 tCt/tTt 0 +EIF2AK3 UCSF GRCh37 2 88874385 88874385 + synonymous_variant Silent SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 123 89 254 0 ENST00000303236.3:c.2616A>G p.Thr872= p.T872= ENST00000303236 NM_004836.5 872 acA/acG 0 +FANCF UCSF GRCh37 11 22646911 22646911 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 65 55 170 0 ENST00000327470.3:c.446A>G p.Asn149Ser p.N149S ENST00000327470 NM_022725.3 149 aAt/aGt 0 +FCRL6 UCSF GRCh37 1 159779338 159779338 + missense_variant Missense_Mutation SNP C C G NOVEL P08_Rec Untested WXS Illumina HiSeq 42 36 99 0 ENST00000368106.3:c.751C>G p.His251Asp p.H251D ENST00000368106 NM_001004310.2 251 Cac/Gac 0 +GGT7 UCSF GRCh37 20 33440238 33440238 + stop_gained Nonsense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 41 42 92 0 ENST00000336431.5:c.1423C>T p.Gln475Ter p.Q475* ENST00000336431 NM_178026.2 475 Cag/Tag 0 +GNAS UCSF GRCh37 20 57429479 57429479 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 20 14 33 0 ENST00000371100.4:c.1159T>C p.Ser387Pro p.S387P ENST00000371100 NM_001077490.1 387 Tca/Cca 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 92 62 143 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFRD2 UCSF GRCh37 3 50326696 50326696 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 13 8 36 0 ENST00000429673.2:c.1067G>A p.Arg356Gln p.R356Q ENST00000429673 356 cGg/cAg 0 +IGSF10 UCSF GRCh37 3 151165459 151165459 + missense_variant Missense_Mutation SNP G G C NOVEL P08_Rec Untested WXS Illumina HiSeq 76 63 139 0 ENST00000282466.3:c.2310C>G p.Asp770Glu p.D770E ENST00000282466 NM_178822.4 770 gaC/gaG 0 +INTS1 UCSF GRCh37 7 1515927 1515927 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 13 8 18 0 ENST00000404767.3:c.5316C>T p.Asp1772= p.D1772= ENST00000404767 NM_001080453.2 1772 gaC/gaT 0 +KIAA0564 UCSF GRCh37 13 42295529 42295529 + missense_variant Missense_Mutation SNP C C A NOVEL P08_Rec Untested WXS Illumina HiSeq 109 59 207 1 ENST00000379310.3:c.2941G>T p.Val981Phe p.V981F ENST00000379310 NM_015058.1 981 Gtc/Ttc 0 +LDHB UCSF GRCh37 12 21791391 21791411 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACTCCACACAGCCACTGTTTA ACTCCACACAGCCACTGTTTA CCTCCACACAGCCCCTGTTT NOVEL P08_Rec Untested WXS Illumina HiSeq 8 0 ENST00000396076.1:c.596-7_609delinsAAACAGGGGCTGTGTGGAGG p.X199_splice ENST00000396076 NM_001174097.1 0 +MAPK14 UCSF GRCh37 6 35996040 35996040 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Rec Untested WXS Illumina HiSeq 14 11 38 0 ENST00000229795.3:c.106G>T p.Gly36Cys p.G36C ENST00000229795 NM_001315.2 36 Ggc/Tgc 0 +MBNL1 UCSF GRCh37 3 152132729 152132729 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 101 71 151 0 ENST00000282486.6:c.175-1G>A p.X59_splice ENST00000282486 0 +MLLT4 UCSF GRCh37 6 168299038 168299038 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P08_Rec Untested WXS Illumina HiSeq 41 0 ENST00000392108.3:c.1473del p.Phe491LeufsTer27 p.F491Lfs*27 ENST00000392108 NM_001040000.2 491 Ttt/tt 0 +MPO UCSF GRCh37 17 56349077 56349077 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 26 24 75 0 ENST00000225275.3:c.1969G>A p.Val657Met p.V657M ENST00000225275 NM_000250.1 657 Gtg/Atg 0 +MSTN UCSF GRCh37 2 190925003 190925003 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 112 82 204 0 ENST00000260950.4:c.532A>G p.Lys178Glu p.K178E ENST00000260950 NM_005259.2 178 Aaa/Gaa 0 +MUC2 UCSF GRCh37 11 1103572 1103572 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Rec Untested WXS Illumina HiSeq 13 2 23 0 ENST00000441003.2:c.8085G>T p.Met2695Ile p.M2695I ENST00000441003 NM_002457.2 2695 atG/atT 0 +MYF5 UCSF GRCh37 12 81110945 81110945 + stop_gained Nonsense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 34 21 46 0 ENST00000228644.3:c.103C>T p.Arg35Ter p.R35* ENST00000228644 NM_005593.2 35 Cga/Tga 0 +MYO1A UCSF GRCh37 12 57423580 57423580 + stop_gained Nonsense_Mutation SNP C C A NOVEL P08_Rec Untested WXS Illumina HiSeq 72 47 93 0 ENST00000442789.2:c.2668G>T p.Glu890Ter p.E890* ENST00000442789 NM_001256041.1 890 Gag/Tag 0 +NKX2-2 UCSF GRCh37 20 21492891 21492892 + inframe_insertion In_Frame_Ins INS - - GAGGCTGGCCAG NOVEL P08_Rec Untested WXS Illumina HiSeq 8 0 ENST00000377142.4:c.492_493insTGGCCAGCCTCC p.Leu164_Ile165insTrpProAlaSer p.L164_I165insWPAS ENST00000377142 NM_002509.3 164 ctc/ctCTGGCCAGCCTCc 0 +NPTX2 UCSF GRCh37 7 98254278 98254278 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 82 78 158 0 ENST00000265634.3:c.688C>T p.Pro230Ser p.P230S ENST00000265634 NM_002523.2 230 Cca/Tca 0 +OR2L2 UCSF GRCh37 1 248202417 248202417 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 166 109 234 0 ENST00000366479.2:c.848T>C p.Met283Thr p.M283T ENST00000366479 NM_001004686.2 283 aTg/aCg 0 +OR51B4 UCSF GRCh37 11 5322448 5322448 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 67 50 163 0 ENST00000380224.1:c.729C>T p.Ser243= p.S243= ENST00000380224 NM_033179.2 243 agC/agT 0 +OR5M9 UCSF GRCh37 11 56230866 56230866 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 29 30 85 0 ENST00000279791.1:c.12C>T p.Phe4= p.F4= ENST00000279791 NM_001004743.1 4 ttC/ttT 0 +OR6N2 UCSF GRCh37 1 158746563 158746563 + missense_variant Missense_Mutation SNP A A T NOVEL P08_Rec Untested WXS Illumina HiSeq 116 86 239 0 ENST00000339258.1:c.863T>A p.Ile288Asn p.I288N ENST00000339258 NM_001005278.1 288 aTt/aAt 0 +PDCL UCSF GRCh37 9 125585446 125585446 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 97 69 178 0 ENST00000259467.4:c.203G>A p.Arg68His p.R68H ENST00000259467 NM_005388.4 68 cGc/cAc 0 +PLD3 UCSF GRCh37 19 40882596 40882596 + stop_gained Nonsense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 33 4 65 0 ENST00000409587.1:c.1100G>A p.Trp367Ter p.W367* ENST00000409587 367 tGg/tAg 0 +PLIN2 UCSF GRCh37 9 19123586 19123586 + missense_variant Missense_Mutation SNP T T A NOVEL P08_Rec Untested WXS Illumina HiSeq 123 72 189 0 ENST00000276914.2:c.286A>T p.Ile96Phe p.I96F ENST00000276914 NM_001122.3 96 Att/Ttt 0 +PRMT5 UCSF GRCh37 14 23396859 23396859 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec somatic WXS Sanger Illumina HiSeq 87 55 110 0 ENST00000324366.8:c.326A>G p.Gln109Arg p.Q109R ENST00000324366 NM_006109.3 109 cAg/cGg 0 +RNASEL UCSF GRCh37 1 182550475 182550475 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 129 105 195 0 ENST00000367559.3:c.1790G>A p.Arg597Gln p.R597Q ENST00000367559 NM_021133.3 597 cGg/cAg 0 +SHISA3 UCSF GRCh37 4 42403378 42403378 + synonymous_variant Silent SNP T T G NOVEL P08_Rec Untested WXS Illumina HiSeq 61 25 101 0 ENST00000319234.4:c.627T>G p.Gly209= p.G209= ENST00000319234 NM_001080505.1 209 ggT/ggG 0 +SLC6A13 UCSF GRCh37 12 332297 332297 + splice_donor_variant Splice_Site SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 29 16 63 0 ENST00000343164.4:c.1414+1G>A p.X472_splice ENST00000343164 NM_016615.4 0 +SLC6A3 UCSF GRCh37 5 1441532 1441532 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 26 18 59 0 ENST00000270349.9:c.360C>T p.Leu120= p.L120= ENST00000270349 NM_001044.4 120 ctC/ctT 0 +SSC5D UCSF GRCh37 19 56001358 56001358 + synonymous_variant Silent SNP A A T NOVEL P08_Rec Untested WXS Illumina HiSeq 3 11 30 0 ENST00000389623.6:c.471A>T p.Thr157= p.T157= ENST00000389623 NM_001144950.1 157 acA/acT 0 +TBCE UCSF GRCh37 1 235600735 235600735 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 57 37 97 0 ENST00000366601.3:c.1062G>A p.Ala354= p.A354= ENST00000366601 354 gcG/gcA 0 +TCP10L2 UCSF GRCh37 6 167585753 167585753 + missense_variant Missense_Mutation SNP G G T NOVEL P08_Rec Untested WXS Illumina HiSeq 27 5 46 0 ENST00000366832.2:c.121G>T p.Asp41Tyr p.D41Y ENST00000366832 NM_001145121.1 41 Gac/Tac 0 +TNRC6A UCSF GRCh37 16 24802604 24802604 + missense_variant Missense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 74 60 153 0 ENST00000395799.3:c.2641G>A p.Asp881Asn p.D881N ENST00000395799 NM_014494.2 881 Gac/Aac 0 +TP53 UCSF GRCh37 17 7577099 7577099 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 7 81 65 0 ENST00000269305.4:c.839G>A p.Arg280Lys p.R280K ENST00000269305 NM_001126112.2 280 aGa/aAa 0 +TTLL3 UCSF GRCh37 3 9852311 9852311 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 15 3 23 0 ENST00000426895.4:c.395C>T p.Pro132Leu p.P132L ENST00000426895 132 cCg/cTg 0 +TTN UCSF GRCh37 2 179568917 179568917 + synonymous_variant Silent SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 127 91 255 0 ENST00000589042.1:c.30180C>T p.Cys10060= p.C10060= ENST00000589042 NM_001267550.1 10060 tgC/tgT 0 +USH2A UCSF GRCh37 1 215901628 215901628 + missense_variant Missense_Mutation SNP A A G NOVEL P08_Rec Untested WXS Illumina HiSeq 85 53 179 0 ENST00000307340.3:c.11810T>C p.Leu3937Pro p.L3937P ENST00000307340 NM_206933.2 3937 cTc/cCc 0 +USH2A UCSF GRCh37 1 216144109 216144109 + missense_variant Missense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 189 27 196 0 ENST00000307340.3:c.6815C>T p.Thr2272Met p.T2272M ENST00000307340 NM_206933.2 2272 aCg/aTg 0 +USH2A UCSF GRCh37 1 216363700 216363700 + missense_variant Missense_Mutation SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 108 66 185 0 ENST00000307340.3:c.4261A>G p.Thr1421Ala p.T1421A ENST00000307340 NM_206933.2 1421 Act/Gct 0 +USP29 UCSF GRCh37 19 57640261 57640261 + missense_variant Missense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 78 9 127 0 ENST00000254181.4:c.218G>A p.Arg73His p.R73H ENST00000254181 NM_020903.2 73 cGt/cAt 0 +WBSCR28 UCSF GRCh37 7 73279585 73279585 + missense_variant Missense_Mutation SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 46 6 38 0 ENST00000320531.2:c.335C>T p.Ala112Val p.A112V ENST00000320531 NM_182504.3 112 gCc/gTc 0 +WDR63 UCSF GRCh37 1 85583512 85583512 + missense_variant Missense_Mutation SNP C C G NOVEL P08_Rec Untested WXS Illumina HiSeq 102 85 194 0 ENST00000294664.6:c.1887C>G p.Asp629Glu p.D629E ENST00000294664 NM_145172.3 629 gaC/gaG 0 +WT1 UCSF GRCh37 11 32449529 32449529 + missense_variant Missense_Mutation SNP G G A NOVEL P08_Rec Untested WXS Illumina HiSeq 11 6 17 0 ENST00000332351.3:c.845C>T p.Ala282Val p.A282V ENST00000332351 NM_024426.4 282 gCt/gTt 0 +XPO6 UCSF GRCh37 16 28146612 28146612 + synonymous_variant Silent SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 70 50 114 0 ENST00000304658.5:c.1368G>A p.Glu456= p.E456= ENST00000304658 NM_015171.3 456 gaG/gaA 0 +ZNF596 UCSF GRCh37 8 193006 193006 + synonymous_variant Silent SNP C C T NOVEL P08_Rec Untested WXS Illumina HiSeq 67 36 89 0 ENST00000398612.1:c.132C>T p.Val44= p.V44= ENST00000398612 NM_001042415.1 44 gtC/gtT 0 +ZNF804B UCSF GRCh37 7 88962812 88962812 + synonymous_variant Silent SNP T T C NOVEL P08_Rec Untested WXS Illumina HiSeq 98 75 209 0 ENST00000333190.4:c.516T>C p.Asn172= p.N172= ENST00000333190 NM_181646.2 172 aaT/aaC 0 +ATRX UCSF GRCh37 X 76954101 76954101 + synonymous_variant Silent SNP A A G NOVEL P09_Pri Untested WXS Illumina HiSeq 8 56 69 0 ENST00000373344.5:c.150T>C p.Ser50= p.S50= ENST00000373344 NM_000489.3 50 tcT/tcC 0 +GAGE2D UCSF GRCh37 X 49208299 49208313 + protein_altering_variant In_Frame_Ins INS CGGCCTAGACCAAGA CGGCCTAGACCAAGA TATTGGCCTAGACCAAGG NOVEL P09_Pri Untested WXS Illumina HiSeq 8 0 ENST00000404720.2:c.28_42delinsTATTGGCCTAGACCAAGG p.Arg10delinsTyrTrp p.R10delinsYW ENST00000404720 NM_001098407.1 10 CGGCCTAGACCAAGA/TATTGGCCTAGACCAAGG 0 +GOLGA6B UCSF GRCh37 15 72954702 72954702 + synonymous_variant Silent SNP A A G snp132_rs74793989 P09_Pri Untested WXS Illumina HiSeq 29 4 76 1 ENST00000421285.3:c.957A>G p.Gln319= p.Q319= ENST00000421285 NM_018652.4 319 caA/caG 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P09_Pri Untested WXS Illumina HiSeq 47 40 81 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +OR4C6 UCSF GRCh37 11 55433016 55433016 + missense_variant Missense_Mutation SNP G G T NOVEL P09_Pri somatic WXS Sanger Illumina HiSeq 59 22 107 0 ENST00000314259.3:c.374G>T p.Cys125Phe p.C125F ENST00000314259 NM_001004704.1 125 tGt/tTt 0 +PDE4DIP UCSF GRCh37 1 144886132 144886132 + synonymous_variant Silent SNP A A G NOVEL P09_Pri Untested WXS Illumina HiSeq 91 33 144 0 ENST00000369356.4:c.3102T>C p.Ile1034= p.I1034= ENST00000369356 NM_014644.5 1034 atT/atC 0 +SLC38A10 UCSF GRCh37 17 79268677 79268677 + synonymous_variant Silent SNP G G A NOVEL P09_Pri Untested WXS Illumina HiSeq 29 11 35 0 ENST00000374759.3:c.45C>T p.Ile15= p.I15= ENST00000374759 NM_001037984.1 15 atC/atT 0 +TP53 UCSF GRCh37 17 7578479 7578479 + missense_variant Missense_Mutation SNP G G C NOVEL P09_Pri Untested WXS Illumina HiSeq 4 32 48 0 ENST00000269305.4:c.451C>G p.Pro151Ala p.P151A ENST00000269305 NM_001126112.2 151 Ccc/Gcc 0 +UGT2A3 UCSF GRCh37 4 69817137 69817138 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P09_Pri Untested WXS Illumina HiSeq 12 0 ENST00000251566.4:c.342dup p.Val115CysfsTer2 p.V115Cfs*2 ENST00000251566 NM_024743.3 114 ttt/ttTt 0 +ABCB4 UCSF GRCh37 7 87079392 87079392 + missense_variant Missense_Mutation SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 124 49 92 0 ENST00000265723.4:c.725G>A p.Ser242Asn p.S242N ENST00000265723 NM_000443.3 242 aGt/aAt 0 +ASB14 UCSF GRCh37 3 57322030 57322030 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P09_Rec Untested WXS Illumina HiSeq 6 0 ENST00000487349.1:c.368del p.Leu123TrpfsTer8 p.L123Wfs*8 ENST00000487349 NM_001142733.2 123 tTg/tg 0 +ATRX UCSF GRCh37 X 76954101 76954101 + synonymous_variant Silent SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 71 42 69 0 ENST00000373344.5:c.150T>C p.Ser50= p.S50= ENST00000373344 NM_000489.3 50 tcT/tcC 0 +C17orf97 UCSF GRCh37 17 263615 263615 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0396,snp132_rs75457484 P09_Rec Untested WXS Illumina HiSeq 45 6 23 1 ENST00000360127.6:c.981C>T p.Pro327= p.P327= ENST00000360127 NM_001013672.4 327 ccC/ccT 0 +CCHCR1 UCSF GRCh37 6 31113527 31113527 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 89 40 49 1 ENST00000396268.3:c.1639C>T p.Pro547Ser p.P547S ENST00000396268 NM_001105563.1 547 Ccc/Tcc 0 +DYSF UCSF GRCh37 2 71896760 71896760 + missense_variant Missense_Mutation SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 130 46 99 0 ENST00000410020.3:c.5668A>G p.Lys1890Glu p.K1890E ENST00000410020 NM_001130987.1 1890 Aag/Gag 0 +DYSF UCSF GRCh37 2 71896763 71896763 + missense_variant Missense_Mutation SNP C C G NOVEL P09_Rec Untested WXS Illumina HiSeq 126 46 97 0 ENST00000410020.3:c.5671C>G p.Gln1891Glu p.Q1891E ENST00000410020 NM_001130987.1 1891 Caa/Gaa 0 +FAM46B UCSF GRCh37 1 27333030 27333038 + frameshift_variant Frame_Shift_Del DEL AGCAACAGG AGCAACAGG CGACA NOVEL P09_Rec Untested WXS Illumina HiSeq 14 0 ENST00000289166.5:c.675_683delinsTGTCG p.Leu226ValfsTer97 p.L226Vfs*97 ENST00000289166 NM_052943.3 225 tcCCTGTTGCTc/tcTGTCGc 0 +FAM48B2 UCSF GRCh37 X 24330042 24330042 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 16 6 18 0 ENST00000536351.1:n.1391G>A *464* ENST00000536351 0 +GAGE2D UCSF GRCh37 X 49208299 49208313 + protein_altering_variant In_Frame_Ins INS CGGCCTAGACCAAGA CGGCCTAGACCAAGA TATTGGCCTAGACCAAGG NOVEL P09_Rec Untested WXS Illumina HiSeq 6 0 ENST00000404720.2:c.28_42delinsTATTGGCCTAGACCAAGG p.Arg10delinsTyrTrp p.R10delinsYW ENST00000404720 NM_001098407.1 10 CGGCCTAGACCAAGA/TATTGGCCTAGACCAAGG 0 +HHIP UCSF GRCh37 4 145580034 145580034 + missense_variant Missense_Mutation SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 95 22 117 0 ENST00000296575.3:c.565A>G p.Arg189Gly p.R189G ENST00000296575 NM_022475.2 189 Aga/Gga 0 +HLA-C UCSF GRCh37 6 31239060 31239060 + missense_variant Missense_Mutation SNP A A G 1000g2010nov_all_0.113,1000g2011may_all_0.1122,snp132_rs114934942 P09_Rec Untested WXS Illumina HiSeq 50 16 31 1 ENST00000376228.5:c.409T>C p.Tyr137His p.Y137H ENST00000376228 NM_002117.5 137 Tat/Cat 0 +HLA-G UCSF GRCh37 6 29797406 29797406 + synonymous_variant Silent SNP G G A snp132_rs79264452 P09_Rec Untested WXS Illumina HiSeq 117 18 90 1 ENST00000428701.1:c.831G>A p.Glu277= p.E277= ENST00000428701 NM_002127.5 277 gaG/gaA 0 +HLA-G UCSF GRCh37 6 29797436 29797436 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.113,snp132_rs115797657 P09_Rec Untested WXS Illumina HiSeq 110 18 74 1 ENST00000428701.1:c.861T>C p.His287= p.H287= ENST00000428701 NM_002127.5 287 caT/caC 0 +HOXB2 UCSF GRCh37 17 46622047 46622047 + missense_variant Missense_Mutation SNP G G C NOVEL P09_Rec Untested WXS Illumina HiSeq 34 5 36 0 ENST00000330070.4:c.227C>G p.Pro76Arg p.P76R ENST00000330070 NM_002145.3 76 cCt/cGt 0 +ICK UCSF GRCh37 6 52880927 52880927 + missense_variant Missense_Mutation SNP C C G NOVEL P09_Rec Untested WXS Illumina HiSeq 120 32 107 0 ENST00000356971.3:c.785G>C p.Arg262Thr p.R262T ENST00000356971 NM_016513.4 262 aGa/aCa 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 119 30 81 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGF2 UCSF GRCh37 11 2154787 2154794 + frameshift_variant Frame_Shift_Del DEL TTGGCGGG TTGGCGGG - NOVEL P09_Rec Untested WXS Illumina HiSeq 10 0 ENST00000434045.2:c.427_434del p.Pro143ValfsTer28 p.P143Vfs*28 ENST00000434045 NM_001127598.1 143 CCCGCCAAg/g 0 +INTS6 UCSF GRCh37 13 51957526 51957529 + frameshift_variant Frame_Shift_Del DEL TGCT TGCT - NOVEL P09_Rec Untested WXS Illumina HiSeq 17 0 ENST00000311234.4:c.1116_1119del p.Ala373Ter p.A373* ENST00000311234 NM_012141.2 372 acAGCA/ac 0 +JARID2 UCSF GRCh37 6 15468893 15468893 + missense_variant Missense_Mutation SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 187 61 85 0 ENST00000341776.2:c.614C>T p.Ser205Leu p.S205L ENST00000341776 NM_004973.3 205 tCa/tTa 0 +MUC4 UCSF GRCh37 3 195507919 195507919 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 36 9 57 1 ENST00000463781.3:c.10532C>T p.Ser3511Phe p.S3511F ENST00000463781 NM_018406.6 3511 tCc/tTc 0 +NUDT10 UCSF GRCh37 X 51075841 51075841 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.07393,1000g2011may_all_0.2097,snp132_rs2625875 P09_Rec Untested WXS Illumina HiSeq 28 4 19 0 ENST00000376006.3:c.24A>G p.Thr8= p.T8= ENST00000376006 NM_153183.2 8 acA/acG 0 +NUDT10 UCSF GRCh37 X 51076024 51076024 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.00397,1000g2011may_all_0.0126,snp132_rs2801626 P09_Rec Untested WXS Illumina HiSeq 36 4 34 0 ENST00000376006.3:c.207G>A p.Glu69= p.E69= ENST00000376006 NM_153183.2 69 gaG/gaA 0 +OAS2 UCSF GRCh37 12 113448284 113448309 + stop_lost,3_prime_UTR_variant Nonstop_Mutation DEL TTCTAGAGATCATCTGGCAATCGCTT TTCTAGAGATCATCTGGCAATCGCTT - NOVEL P09_Rec Untested WXS Illumina HiSeq 26 0 ENST00000342315.4:c.2157_*22del *719* ENST00000342315 NM_016817.2 719 0 +OR10C1 UCSF GRCh37 6 29408542 29408542 + missense_variant Missense_Mutation SNP C C G NOVEL P09_Rec Untested WXS Illumina HiSeq 165 105 115 0 ENST00000444197.2:c.750C>G p.Phe250Leu p.F250L ENST00000444197 NM_013941.3 250 ttC/ttG 0 +OR11G2 UCSF GRCh37 14 20665692 20665692 + synonymous_variant Silent SNP T T C NOVEL P09_Rec Untested WXS Illumina HiSeq 87 36 66 0 ENST00000357366.3:c.198T>C p.Phe66= p.F66= ENST00000357366 NM_001005503.1 66 ttT/ttC 0 +OR4C6 UCSF GRCh37 11 55433016 55433016 + missense_variant Missense_Mutation SNP G G T NOVEL P09_Rec somatic WXS Sanger Illumina HiSeq 87 41 107 0 ENST00000314259.3:c.374G>T p.Cys125Phe p.C125F ENST00000314259 NM_001004704.1 125 tGt/tTt 0 +PCF11 UCSF GRCh37 11 82877718 82877718 + synonymous_variant Silent SNP T T C NOVEL P09_Rec Untested WXS Illumina HiSeq 179 131 184 0 ENST00000298281.4:c.1779T>C p.Ser593= p.S593= ENST00000298281 NM_015885.3 593 tcT/tcC 0 +PDE4DIP UCSF GRCh37 1 144886132 144886132 + synonymous_variant Silent SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 171 32 144 0 ENST00000369356.4:c.3102T>C p.Ile1034= p.I1034= ENST00000369356 NM_014644.5 1034 atT/atC 0 +PHF3 UCSF GRCh37 6 64419048 64419048 + missense_variant,splice_region_variant Missense_Mutation SNP A A G NOVEL P09_Rec Untested WXS Illumina HiSeq 91 36 82 0 ENST00000262043.3:c.3713A>G p.Asp1238Gly p.D1238G ENST00000262043 1238 gAc/gGc 0 +PPFIBP1 UCSF GRCh37 12 27825398 27825415 + inframe_deletion,splice_region_variant In_Frame_Del DEL AACTGTGTGATAAACTTT AACTGTGTGATAAACTTT - NOVEL P09_Rec Untested WXS Illumina HiSeq 9 0 ENST00000318304.8:c.1352_1369del p.Gln451_Leu456del p.Q451_L456del ENST00000318304 NM_177444.2 451 cAACTGTGTGATAAACTTTta/cta 0 +PSMD5 UCSF GRCh37 9 123595695 123595695 + synonymous_variant Silent SNP C C T NOVEL P09_Rec Untested WXS Illumina HiSeq 164 82 134 0 ENST00000210313.3:c.213G>A p.Leu71= p.L71= ENST00000210313 NM_005047.3 71 ttG/ttA 0 +SLC28A2 UCSF GRCh37 15 45561641 45561641 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 111 25 96 0 ENST00000347644.3:c.1474G>A p.Glu492Lys p.E492K ENST00000347644 NM_004212.3 492 Gag/Aag 0 +SLC28A2 UCSF GRCh37 15 45561643 45561643 + missense_variant Missense_Mutation SNP G G T NOVEL P09_Rec Untested WXS Illumina HiSeq 114 26 97 0 ENST00000347644.3:c.1476G>T p.Glu492Asp p.E492D ENST00000347644 NM_004212.3 492 gaG/gaT 0 +SLC38A10 UCSF GRCh37 17 79268677 79268677 + synonymous_variant Silent SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 41 14 35 0 ENST00000374759.3:c.45C>T p.Ile15= p.I15= ENST00000374759 NM_001037984.1 15 atC/atT 0 +TAOK3 UCSF GRCh37 12 118588939 118588939 + missense_variant Missense_Mutation SNP G G T NOVEL P09_Rec Untested WXS Illumina HiSeq 102 36 82 0 ENST00000392533.3:c.2560C>A p.Gln854Lys p.Q854K ENST00000392533 NM_016281.3 854 Cag/Aag 0 +TAOK3 UCSF GRCh37 12 118588940 118588940 + synonymous_variant Silent SNP A A T NOVEL P09_Rec Untested WXS Illumina HiSeq 101 36 82 0 ENST00000392533.3:c.2559T>A p.Leu853= p.L853= ENST00000392533 NM_016281.3 853 ctT/ctA 0 +TEX11 UCSF GRCh37 X 70093131 70093131 + missense_variant Missense_Mutation SNP C C A NOVEL P09_Rec Untested WXS Illumina HiSeq 38 33 52 0 ENST00000395889.2:c.231G>T p.Trp77Cys p.W77C ENST00000395889 NM_001003811.1 77 tgG/tgT 0 +TMED1 UCSF GRCh37 19 10945980 10945980 + missense_variant Missense_Mutation SNP T T C NOVEL P09_Rec Untested WXS Illumina HiSeq 72 20 54 0 ENST00000214869.2:c.233A>G p.Gln78Arg p.Q78R ENST00000214869 NM_006858.3 78 cAg/cGg 0 +TNF UCSF GRCh37 6 31544909 31544909 + synonymous_variant Silent SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 110 38 64 0 ENST00000449264.2:c.297G>A p.Glu99= p.E99= ENST00000449264 NM_000594.3 99 gaG/gaA 0 +TNF UCSF GRCh37 6 31545161 31545161 + synonymous_variant Silent SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 112 29 65 0 ENST00000449264.2:c.549G>A p.Glu183= p.E183= ENST00000449264 NM_000594.3 183 gaG/gaA 0 +TNNI1 UCSF GRCh37 1 201380601 201380601 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 47 8 42 0 ENST00000361379.4:c.340C>T p.Arg114Cys p.R114C ENST00000361379 NM_003281.3 114 Cgt/Tgt 0 +TNNT3 UCSF GRCh37 11 1955222 1955222 + missense_variant Missense_Mutation SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 21 13 33 0 ENST00000278317.6:c.350G>A p.Arg117His p.R117H ENST00000278317 NM_006757.3 117 cGc/cAc 0 +TP53 UCSF GRCh37 17 7578479 7578479 + missense_variant Missense_Mutation SNP G G C NOVEL P09_Rec Untested WXS Illumina HiSeq 31 38 48 0 ENST00000269305.4:c.451C>G p.Pro151Ala p.P151A ENST00000269305 NM_001126112.2 151 Ccc/Gcc 0 +UNC13A UCSF GRCh37 19 17756853 17756853 + missense_variant Missense_Mutation SNP C C G NOVEL P09_Rec Untested WXS Illumina HiSeq 92 54 58 0 ENST00000519716.2:c.2112G>C p.Gln704His p.Q704H ENST00000519716 NM_001080421.2 704 caG/caC 0 +UNC93B1 UCSF GRCh37 11 67763353 67763353 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P09_Rec Untested WXS Illumina HiSeq 35 7 22 1 ENST00000227471.2:c.1089C>T p.Gly363= p.G363= ENST00000227471 NM_030930.2 363 ggC/ggT 0 +USP28 UCSF GRCh37 11 113672332 113672335 + frameshift_variant Frame_Shift_Del DEL ATTA ATTA - NOVEL P09_Rec Untested WXS Illumina HiSeq 26 0 ENST00000003302.4:c.2928_2931del p.Ile976MetfsTer2 p.I976Mfs*2 ENST00000003302 NM_020886.2 976 atTAAT/at 0 +VPS35 UCSF GRCh37 16 46708258 46708258 + synonymous_variant Silent SNP T T C NOVEL P09_Rec Untested WXS Illumina HiSeq 88 40 78 0 ENST00000299138.7:c.1128A>G p.Thr376= p.T376= ENST00000299138 NM_018206.4 376 acA/acG 0 +ZNF292 UCSF GRCh37 6 87965102 87965103 + frameshift_variant Frame_Shift_Ins INS - - C NOVEL P09_Rec Untested WXS Illumina HiSeq 45 0 ENST00000369577.3:c.1757dup p.His587SerfsTer7 p.H587Sfs*7 ENST00000369577 NM_015021.1 585 -/C 0 +ABCD1 UCSF GRCh37 X 152991314 152991314 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri somatic WXS Sanger Illumina HiSeq 12 20 108 0 ENST00000218104.3:c.593C>T p.Thr198Met p.T198M ENST00000218104 NM_000033.3 198 aCg/aTg 0 +ADCK4 UCSF GRCh37 19 41208533 41208533 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 37 29 92 0 ENST00000324464.3:c.865C>T p.Arg289Cys p.R289C ENST00000324464 NM_024876.3 289 Cgt/Tgt 0 +ARHGEF9 UCSF GRCh37 X 62858032 62858032 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Pri Untested WXS Illumina HiSeq 11 12 49 0 ENST00000253401.6:c.1427A>G p.Asn476Ser p.N476S ENST00000253401 NM_015185.2 476 aAc/aGc 0 +ASPSCR1 UCSF GRCh37 17 79968702 79968702 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 13 9 55 1 ENST00000306729.7:c.1195G>A p.Asp399Asn p.D399N ENST00000306729 NM_001251888.1 399 Gac/Aac 0 +ATRX UCSF GRCh37 X 76814225 76814225 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Pri somatic WXS Sanger Illumina HiSeq 52 42 168 0 ENST00000373344.5:c.6419A>G p.Asn2140Ser p.N2140S ENST00000373344 NM_000489.3 2140 aAt/aGt 0 +CCDC151 UCSF GRCh37 19 11537720 11537720 + synonymous_variant Silent SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 13 12 52 0 ENST00000356392.4:c.585G>A p.Ala195= p.A195= ENST00000356392 NM_145045.4 195 gcG/gcA 0 +DAGLA UCSF GRCh37 11 61505189 61505189 + synonymous_variant Silent SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 40 17 82 0 ENST00000257215.5:c.1545C>T p.Phe515= p.F515= ENST00000257215 NM_006133.2 515 ttC/ttT 0 +DSCAM UCSF GRCh37 21 41684176 41684176 + stop_gained Nonsense_Mutation SNP T T A NOVEL P10_Pri Untested WXS Illumina HiSeq 52 16 136 0 ENST00000400454.1:c.1894A>T p.Lys632Ter p.K632* ENST00000400454 NM_001271534.1 632 Aag/Tag 0 +FAM55A UCSF GRCh37 11 114392826 114392826 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Pri Untested WXS Illumina HiSeq 62 28 186 0 ENST00000251921.2:c.1082A>G p.Lys361Arg p.K361R ENST00000251921 NM_152315.2 361 aAg/aGg 0 +FAM75C2 UCSF GRCh37 9 90746733 90746733 + non_coding_transcript_exon_variant RNA SNP C C G NOVEL P10_Pri Untested WXS Illumina HiSeq 43 25 267 1 ENST00000324915.5:n.1417G>C *473* ENST00000324915 0 +FLG UCSF GRCh37 1 152280068 152280068 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 30 26 214 0 ENST00000368799.1:c.7294G>A p.Gly2432Arg p.G2432R ENST00000368799 NM_002016.1 2432 Ggg/Agg 0 +FRMPD4 UCSF GRCh37 X 12734380 12734380 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Pri Untested WXS Illumina HiSeq 44 36 188 1 ENST00000380682.1:c.1802A>G p.Tyr601Cys p.Y601C ENST00000380682 NM_014728.3 601 tAt/tGt 0 +GABRE UCSF GRCh37 X 151123325 151123325 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Pri Untested WXS Illumina HiSeq 24 13 57 0 ENST00000370328.3:c.1369T>C p.Phe457Leu p.F457L ENST00000370328 NM_004961.3 457 Ttc/Ctc 0 +GTPBP1 UCSF GRCh37 22 39123237 39123237 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 7 33 150 1 ENST00000216044.5:c.1421G>A p.Arg474Gln p.R474Q ENST00000216044 NM_004286.4 474 cGg/cAg 0 +HS3ST3A1 UCSF GRCh37 17 13400067 13400067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 35 16 124 0 ENST00000284110.1:c.668G>A p.Arg223Gln p.R223Q ENST00000284110 NM_006042.1 223 cGg/cAg 0 +HS3ST3B1 UCSF GRCh37 17 14248413 14248413 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 2 14 46 0 ENST00000360954.2:c.623G>A p.Arg208Gln p.R208Q ENST00000360954 NM_006041.1 208 cGg/cAg 0 +HTRA1 UCSF GRCh37 10 124248504 124248504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 31 33 132 0 ENST00000368984.3:c.559G>A p.Glu187Lys p.E187K ENST00000368984 NM_002775.4 187 Gaa/Aaa 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri somatic WXS Sanger Illumina HiSeq 56 46 125 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KCNJ12 UCSF GRCh37 17 21319232 21319232 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 61 10 115 0 ENST00000583088.1:c.578C>T p.Thr193Met p.T193M ENST00000583088 NM_021012.4 193 aCg/aTg 0 +KRTAP4-1 UCSF GRCh37 17 39340795 39340795 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.020 P10_Pri Untested WXS Illumina HiSeq 34 6 97 1 ENST00000398472.1:c.312T>C p.Arg104= p.R104= ENST00000398472 104 cgT/cgC 0 +LCA5L UCSF GRCh37 21 40800200 40800200 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Pri Untested WXS Illumina HiSeq 67 8 182 0 ENST00000358268.2:c.220G>A p.Asp74Asn p.D74N ENST00000358268 74 Gat/Aat 0 +MYH1 UCSF GRCh37 17 10406468 10406468 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Pri Untested WXS Illumina HiSeq 18 24 218 1 ENST00000226207.5:c.2789C>A p.Ala930Asp p.A930D ENST00000226207 NM_005963.3 930 gCt/gAt 0 +MYH14 UCSF GRCh37 19 50795615 50795615 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Pri Untested WXS Illumina HiSeq 21 4 36 2 ENST00000601313.1:c.5225G>T p.Gly1742Val p.G1742V ENST00000601313 NM_001145809.1 1742 gGc/gTc 0 +NBPF4 UCSF GRCh37 1 108769307 108769307 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.062,1000g2011may_all_0.2082,snp132_rs2582071 P10_Pri Untested WXS Illumina HiSeq 34 5 70 1 ENST00000415641.3:c.1869C>T p.Ser623= p.S623= ENST00000415641 NM_001143989.2 623 agC/agT 0 +NLGN4X UCSF GRCh37 X 5821576 5821576 + synonymous_variant Silent SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 26 23 150 0 ENST00000381095.3:c.1143C>T p.Asp381= p.D381= ENST00000381095 NM_181332.1 381 gaC/gaT 0 +OR4K15 UCSF GRCh37 14 20444624 20444624 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Pri Untested WXS Illumina HiSeq 36 26 172 0 ENST00000305051.5:c.947A>G p.Lys316Arg p.K316R ENST00000305051 NM_001005486.1 316 aAa/aGa 0 +PLXNA4 UCSF GRCh37 7 131831322 131831322 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 51 25 172 0 ENST00000359827.3:c.5002C>T p.Arg1668Trp p.R1668W ENST00000359827 1668 Cgg/Tgg 0 +PTK2 UCSF GRCh37 8 141829029 141829043 + inframe_deletion In_Frame_Del DEL GGATCTCAAAGAATT GGATCTCAAAGAATT - NOVEL P10_Pri Untested WXS Illumina HiSeq 109 0 ENST00000340930.3:c.725_739del p.Lys242_Leu247delinsMet p.K242_L247delinsM ENST00000340930 NM_001199649.1 242 aAATTCTTTGAGATCCtg/atg 0 +S100PBP UCSF GRCh37 1 33292145 33292145 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Pri Untested WXS Illumina HiSeq 62 38 175 0 ENST00000373475.5:c.445G>T p.Ala149Ser p.A149S ENST00000373475 NM_022753.3 149 Gca/Tca 0 +SORBS2 UCSF GRCh37 4 186544879 186544879 + synonymous_variant Silent SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 43 23 118 0 ENST00000355634.5:c.1992C>T p.Pro664= p.P664= ENST00000355634 NM_001270771.1 664 ccC/ccT 0 +SSBP2 UCSF GRCh37 5 80733256 80733256 + missense_variant Missense_Mutation SNP A A C NOVEL P10_Pri Untested WXS Illumina HiSeq 70 38 164 0 ENST00000320672.4:c.950T>G p.Ile317Ser p.I317S ENST00000320672 NM_001256732.1 317 aTt/aGt 0 +TMEM214 UCSF GRCh37 2 27261943 27261943 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 23 7 90 0 ENST00000238788.9:c.1436G>A p.Arg479Gln p.R479Q ENST00000238788 NM_017727.4 479 cGg/cAg 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Pri somatic WXS Sanger Illumina HiSeq 3 24 83 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TRIM42 UCSF GRCh37 3 140407071 140407071 + missense_variant Missense_Mutation SNP T T G NOVEL P10_Pri Untested WXS Illumina HiSeq 38 18 156 0 ENST00000286349.3:c.1547T>G p.Ile516Ser p.I516S ENST00000286349 NM_152616.4 516 aTt/aGt 0 +ZDHHC18 UCSF GRCh37 1 27177632 27177632 + synonymous_variant Silent SNP G G A NOVEL P10_Pri Untested WXS Illumina HiSeq 18 18 122 0 ENST00000374142.4:c.846G>A p.Leu282= p.L282= ENST00000374142 NM_032283.2 282 ttG/ttA 0 +ZNF527 UCSF GRCh37 19 37880574 37880574 + synonymous_variant Silent SNP T T C NOVEL P10_Pri Untested WXS Illumina HiSeq 53 41 132 0 ENST00000436120.2:c.1623T>C p.Leu541= p.L541= ENST00000436120 NM_032453.1 541 ctT/ctC 0 +A2ML1 UCSF GRCh37 12 8975830 8975830 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 77 173 0 ENST00000299698.7:c.115G>A p.Val39Ile p.V39I ENST00000299698 NM_144670.4 39 Gtt/Att 0 +AAMP UCSF GRCh37 2 219131576 219131576 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 51 94 0 ENST00000248450.4:c.528C>T p.Asp176= p.D176= ENST00000248450 176 gaC/gaT 0 +AANAT UCSF GRCh37 17 74465899 74465899 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 8 14 0 ENST00000250615.3:c.606G>A p.Ala202= p.A202= ENST00000250615 NM_001166579.1 202 gcG/gcA 0 +ABAT UCSF GRCh37 16 8866640 8866640 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 42 140 0 ENST00000396600.2:c.820G>A p.Glu274Lys p.E274K ENST00000396600 NM_000663.4 274 Gag/Aag 0 +ABCA1 UCSF GRCh37 9 107588071 107588071 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 189 72 168 0 ENST00000374736.3:c.2435G>A p.Ser812Asn p.S812N ENST00000374736 NM_005502.3 812 aGt/aAt 0 +ABCA13 UCSF GRCh37 7 48318903 48318903 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 77 98 0 ENST00000435803.1:c.8112C>T p.Gly2704= p.G2704= ENST00000435803 NM_152701.3 2704 ggC/ggT 0 +ABCA2 UCSF GRCh37 9 139910305 139910305 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 21 43 0 ENST00000341511.6:c.3336G>A p.Glu1112= p.E1112= ENST00000341511 NM_212533.2 1112 gaG/gaA 0 +ABCA5 UCSF GRCh37 17 67260942 67260942 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 38 124 0 ENST00000392676.3:c.3249G>A p.Leu1083= p.L1083= ENST00000392676 1083 ttG/ttA 0 +ABCA9 UCSF GRCh37 17 67031836 67031836 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 83 153 0 ENST00000340001.4:c.907G>A p.Val303Ile p.V303I ENST00000340001 NM_080283.3 303 Gtc/Atc 0 +ABCB1 UCSF GRCh37 7 87168620 87168620 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 35 87 0 ENST00000265724.3:c.2361G>A p.Arg787= p.R787= ENST00000265724 NM_000927.4 787 cgG/cgA 0 +ABCB4 UCSF GRCh37 7 87076349 87076349 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 37 87 0 ENST00000265723.4:c.1005+1G>A p.X335_splice ENST00000265723 NM_000443.3 0 +ABCC11 UCSF GRCh37 16 48220964 48220964 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 75 157 0 ENST00000394747.1:c.2971G>A p.Glu991Lys p.E991K ENST00000394747 NM_033151.3 991 Gag/Aag 0 +ABCC11 UCSF GRCh37 16 48264461 48264461 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 38 81 0 ENST00000394747.1:c.123C>T p.Gly41= p.G41= ENST00000394747 NM_033151.3 41 ggC/ggT 0 +ABCC2 UCSF GRCh37 10 101567257 101567257 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 59 139 0 ENST00000370449.4:c.1647C>T p.Val549= p.V549= ENST00000370449 NM_000392.3 549 gtC/gtT 0 +ABCC3 UCSF GRCh37 17 48765012 48765012 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 70 146 0 ENST00000285238.8:c.4396G>A p.Ala1466Thr p.A1466T ENST00000285238 NM_003786.3 1466 Gct/Act 0 +ABCD1 UCSF GRCh37 X 152991314 152991314 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 58 58 108 0 ENST00000218104.3:c.593C>T p.Thr198Met p.T198M ENST00000218104 NM_000033.3 198 aCg/aTg 0 +ABHD11 UCSF GRCh37 7 73152057 73152057 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 23 48 0 ENST00000222800.3:c.297G>A p.Thr99= p.T99= ENST00000222800 NM_148912.2 99 acG/acA 0 +ABHD12 UCSF GRCh37 20 25275646 25275646 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 58 153 0 ENST00000376542.3:c.1178C>T p.Ser393Phe p.S393F ENST00000376542 NM_015600.4 393 tCc/tTc 0 +ABHD14B UCSF GRCh37 3 52004156 52004156 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 54 94 0 ENST00000483233.1:c.256G>A p.Glu86Lys p.E86K ENST00000483233 86 Gag/Aag 0 +ABL1 UCSF GRCh37 9 133760004 133760004 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 72 28 47 0 ENST00000318560.5:c.2327C>T p.Thr776Ile p.T776I ENST00000318560 NM_005157.4 776 aCc/aTc 0 +ABL1 UCSF GRCh37 9 133750256 133750256 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 142 66 163 0 ENST00000318560.5:c.1087G>A p.Asp363Asn p.D363N ENST00000318560 NM_005157.4 363 Gat/Aat 0 +ABT1 UCSF GRCh37 6 26598177 26598177 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 44 75 0 ENST00000274849.1:c.277G>A p.Ala93Thr p.A93T ENST00000274849 NM_013375.3 93 Gct/Act 0 +ACAD11 UCSF GRCh37 3 132322080 132322080 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 66 173 0 ENST00000264990.6:c.1614G>A p.Trp538Ter p.W538* ENST00000264990 NM_032169.4 538 tgG/tgA 0 +ACAP1 UCSF GRCh37 17 7247260 7247260 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 22 24 1 ENST00000158762.3:c.654G>A p.Lys218= p.K218= ENST00000158762 NM_014716.3 218 aaG/aaA 0 +ACCN3 UCSF GRCh37 7 150746101 150746101 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 66 89 0 ENST00000297512.8:c.129G>A p.Gly43= p.G43= ENST00000297512 43 ggG/ggA 0 +ACCN5 UCSF GRCh37 4 156757966 156757966 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 74 157 0 ENST00000537611.2:c.1110C>T p.Asn370= p.N370= ENST00000537611 NM_017419.2 370 aaC/aaT 0 +ACCSL UCSF GRCh37 11 44077841 44077841 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 1 42 80 0 ENST00000378832.1:c.1292C>T p.Thr431Ile p.T431I ENST00000378832 NM_001031854.2 431 aCc/aTc 0 +ACHE UCSF GRCh37 7 100490847 100490847 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 34 55 0 ENST00000302913.4:c.1007G>A p.Gly336Glu p.G336E ENST00000302913 NM_015831.2 336 gGa/gAa 0 +ACOT11 UCSF GRCh37 1 55073742 55073742 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 31 55 0 ENST00000371316.3:c.1629+1G>A p.X543_splice ENST00000371316 NM_015547.3 0 +ACOT11 UCSF GRCh37 1 55065014 55065014 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 25 113 0 ENST00000371316.3:c.810C>T p.Phe270= p.F270= ENST00000371316 NM_015547.3 270 ttC/ttT 0 +ACOXL UCSF GRCh37 2 111542360 111542360 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 51 104 0 ENST00000439055.1:c.127C>T p.Leu43Phe p.L43F ENST00000439055 NM_001142807.1 43 Ctc/Ttc 0 +ACPT UCSF GRCh37 19 51297182 51297182 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 74 177 0 ENST00000270593.1:c.816G>A p.Arg272= p.R272= ENST00000270593 NM_033068.2 272 cgG/cgA 0 +ACSL4 UCSF GRCh37 X 108924505 108924505 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 74 174 0 ENST00000340800.2:c.629G>A p.Ser210Asn p.S210N ENST00000340800 NM_022977.2 210 aGt/aAt 0 +ACSL6 UCSF GRCh37 5 131309079 131309079 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 50 100 0 ENST00000379264.2:c.1083C>T p.Cys361= p.C361= ENST00000379264 NM_001009185.2 361 tgC/tgT 0 +ACSM1 UCSF GRCh37 16 20702440 20702440 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 77 190 0 ENST00000307493.4:c.71C>T p.Pro24Leu p.P24L ENST00000307493 NM_052956.2 24 cCt/cTt 0 +ACSM1 UCSF GRCh37 16 20681275 20681275 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 53 103 0 ENST00000307493.4:c.786C>T p.Val262= p.V262= ENST00000307493 NM_052956.2 262 gtC/gtT 0 +ACSM5 UCSF GRCh37 16 20430602 20430602 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 56 108 0 ENST00000331849.4:c.468C>T p.Tyr156= p.Y156= ENST00000331849 NM_017888.2 156 taC/taT 0 +ACTL7B UCSF GRCh37 9 111617245 111617245 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 55 98 1 ENST00000374667.3:c.966C>T p.Cys322= p.C322= ENST00000374667 NM_006686.3 322 tgC/tgT 0 +ACTR1B UCSF GRCh37 2 98275057 98275057 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 49 121 0 ENST00000289228.5:c.490G>A p.Val164Ile p.V164I ENST00000289228 NM_005735.3 164 Gtc/Atc 0 +ACTRT2 UCSF GRCh37 1 2938970 2938970 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 49 111 0 ENST00000378404.2:c.720G>A p.Arg240= p.R240= ENST00000378404 NM_080431.4 240 agG/agA 0 +ACVR1C UCSF GRCh37 2 158443801 158443801 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 105 253 0 ENST00000243349.8:c.202G>A p.Glu68Lys p.E68K ENST00000243349 NM_001111032.1 68 Gaa/Aaa 0 +ADAD2 UCSF GRCh37 16 84230287 84230287 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 67 106 0 ENST00000268624.3:c.1807G>A p.Ala603Thr p.A603T ENST00000268624 NM_139174.3 603 Gcc/Acc 0 +ADAM11 UCSF GRCh37 17 42855391 42855391 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 65 147 0 ENST00000200557.6:c.2142C>T p.Pro714= p.P714= ENST00000200557 NM_002390.4 714 ccC/ccT 0 +ADAM19 UCSF GRCh37 5 156915317 156915317 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 77 153 0 ENST00000257527.4:c.2506C>T p.Pro836Ser p.P836S ENST00000257527 NM_033274.4 836 Cca/Tca 0 +ADAM19 UCSF GRCh37 5 156915418 156915418 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 43 104 0 ENST00000257527.4:c.2405C>T p.Ser802Phe p.S802F ENST00000257527 NM_033274.4 802 tCc/tTc 0 +ADAM23 UCSF GRCh37 2 207310049 207310049 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 61 138 0 ENST00000264377.3:c.233C>T p.Thr78Ile p.T78I ENST00000264377 NM_003812.3 78 aCt/aTt 0 +ADAMTS14 UCSF GRCh37 10 72498678 72498678 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 27 62 0 ENST00000373208.1:c.1689G>A p.Lys563= p.K563= ENST00000373208 NM_139155.2 563 aaG/aaA 0 +ADAMTS16 UCSF GRCh37 5 5319220 5319220 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 37 83 0 ENST00000274181.7:c.3644G>A p.Cys1215Tyr p.C1215Y ENST00000274181 NM_139056.2 1215 tGc/tAc 0 +ADAMTS2 UCSF GRCh37 5 178699957 178699957 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 27 86 0 ENST00000251582.7:c.643C>T p.Pro215Ser p.P215S ENST00000251582 NM_014244.4 215 Cca/Tca 0 +ADAMTS5 UCSF GRCh37 21 28327088 28327088 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 48 127 0 ENST00000284987.5:c.1207C>T p.His403Tyr p.H403Y ENST00000284987 NM_007038.3 403 Cac/Tac 0 +ADAMTS7 UCSF GRCh37 15 79051788 79051788 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 8 19 0 ENST00000388820.4:c.5036G>A p.Gly1679Asp p.G1679D ENST00000388820 NM_014272.3 1679 gGc/gAc 0 +ADAMTS8 UCSF GRCh37 11 130275496 130275496 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 52 98 0 ENST00000257359.6:c.2627C>T p.Pro876Leu p.P876L ENST00000257359 NM_007037.4 876 cCc/cTc 0 +ADCK4 UCSF GRCh37 19 41208533 41208533 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 53 92 0 ENST00000324464.3:c.865C>T p.Arg289Cys p.R289C ENST00000324464 NM_024876.3 289 Cgt/Tgt 0 +ADCK5 UCSF GRCh37 8 145616355 145616355 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 145 40 83 0 ENST00000308860.6:c.565G>A p.Asp189Asn p.D189N ENST00000308860 NM_174922.4 189 Gac/Aac 0 +ADCY4 UCSF GRCh37 14 24798336 24798336 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 37 78 0 ENST00000310677.4:c.1455G>A p.Trp485Ter p.W485* ENST00000310677 NM_001198568.1 485 tgG/tgA 0 +ADCY5 UCSF GRCh37 3 123049809 123049809 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 35 97 0 ENST00000462833.1:c.1573G>A p.Gly525Arg p.G525R ENST00000462833 NM_183357.2 525 Ggg/Agg 0 +ADCY8 UCSF GRCh37 8 131922112 131922112 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 285 73 128 0 ENST00000286355.5:c.1482G>A p.Arg494= p.R494= ENST00000286355 NM_001115.2 494 agG/agA 0 +ADIPOR2 UCSF GRCh37 12 1895171 1895171 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 83 177 0 ENST00000357103.4:c.1094G>A p.Gly365Asp p.G365D ENST00000357103 NM_024551.2 365 gGt/gAt 0 +ADNP UCSF GRCh37 20 49508225 49508225 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 134 118 181 0 ENST00000396029.3:c.3026G>A p.Ser1009Asn p.S1009N ENST00000396029 NM_015339.2 1009 aGt/aAt 0 +ADNP2 UCSF GRCh37 18 77893588 77893588 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 67 177 0 ENST00000262198.4:c.292G>A p.Asp98Asn p.D98N ENST00000262198 NM_014913.3 98 Gat/Aat 0 +ADPRHL2 UCSF GRCh37 1 36557297 36557297 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 64 156 0 ENST00000373178.4:c.387C>T p.Asn129= p.N129= ENST00000373178 NM_017825.2 129 aaC/aaT 0 +AFAP1 UCSF GRCh37 4 7870389 7870389 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 19 55 0 ENST00000420658.1:c.185C>T p.Pro62Leu p.P62L ENST00000420658 NM_001134647.1 62 cCt/cTt 0 +AFAP1 UCSF GRCh37 4 7774726 7774726 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 23 46 0 ENST00000420658.1:c.2074C>T p.Gln692Ter p.Q692* ENST00000420658 NM_001134647.1 692 Cag/Tag 0 +AFG3L2 UCSF GRCh37 18 12363780 12363780 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 57 128 0 ENST00000269143.3:c.627+1G>A p.X209_splice ENST00000269143 NM_006796.2 0 +AFM UCSF GRCh37 4 74347532 74347533 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 0 ENST00000226355.3:c.47dup p.Leu16PhefsTer3 p.L16Ffs*3 ENST00000226355 NM_001133.2 14 ttt/tTtt 0 +AGAP1 UCSF GRCh37 2 236817473 236817473 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 81 178 0 ENST00000304032.8:c.1247C>T p.Ala416Val p.A416V ENST00000304032 NM_001037131.2 416 gCc/gTc 0 +AGAP2 UCSF GRCh37 12 58126730 58126730 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 108 211 0 ENST00000547588.1:c.1582G>A p.Gly528Arg p.G528R ENST00000547588 NM_001122772.2 528 Gga/Aga 0 +AGBL4 UCSF GRCh37 1 50163095 50163095 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 71 192 0 ENST00000371839.1:c.172G>A p.Val58Met p.V58M ENST00000371839 NM_032785.3 58 Gtg/Atg 0 +AGGF1 UCSF GRCh37 5 76355552 76355552 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 55 150 0 ENST00000312916.7:c.1828C>T p.Pro610Ser p.P610S ENST00000312916 NM_018046.4 610 Cct/Tct 0 +AGPAT9 UCSF GRCh37 4 84516040 84516040 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 120 112 221 0 ENST00000395226.2:c.781G>A p.Ala261Thr p.A261T ENST00000395226 NM_001256421.1 261 Gct/Act 0 +AGPAT9 UCSF GRCh37 4 84519800 84519800 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 27 86 0 ENST00000395226.2:c.1129G>A p.Gly377Arg p.G377R ENST00000395226 NM_001256421.1 377 Gga/Aga 0 +AGRN UCSF GRCh37 1 978819 978819 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 11 36 0 ENST00000379370.2:c.1585G>A p.Ala529Thr p.A529T ENST00000379370 NM_198576.3 529 Gcg/Acg 0 +AHI1 UCSF GRCh37 6 135787148 135787148 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 152 126 222 0 ENST00000367800.4:c.553G>A p.Asp185Asn p.D185N ENST00000367800 NM_001134830.1 185 Gat/Aat 0 +AHNAK UCSF GRCh37 11 62288699 62288699 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 122 125 263 0 ENST00000378024.4:c.13190C>T p.Pro4397Leu p.P4397L ENST00000378024 NM_001620.2 4397 cCc/cTc 0 +AHNAK UCSF GRCh37 11 62288419 62288419 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 119 93 180 1 ENST00000378024.4:c.13470G>A p.Gly4490= p.G4490= ENST00000378024 NM_001620.2 4490 ggG/ggA 0 +AHNAK UCSF GRCh37 11 62297032 62297032 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 116 224 0 ENST00000378024.4:c.4857G>A p.Lys1619= p.K1619= ENST00000378024 NM_001620.2 1619 aaG/aaA 0 +AHNAK UCSF GRCh37 11 62287342 62287342 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 79 190 0 ENST00000378024.4:c.14547C>T p.Ile4849= p.I4849= ENST00000378024 NM_001620.2 4849 atC/atT 0 +AHNAK2 UCSF GRCh37 14 105423788 105423788 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 17 35 0 ENST00000333244.5:c.172G>A p.Val58Ile p.V58I ENST00000333244 NM_138420.2 58 Gtc/Atc 0 +AHRR UCSF GRCh37 5 422934 422934 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 33 73 0 ENST00000316418.5:c.544C>T p.Pro182Ser p.P182S ENST00000316418 NM_020731.4 182 Ccc/Tcc 0 +AICDA UCSF GRCh37 12 8758005 8758005 + missense_variant Missense_Mutation SNP A A T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 47 104 0 ENST00000229335.6:c.233T>A p.Val78Asp p.V78D ENST00000229335 NM_020661.2 78 gTc/gAc 0 +AIPL1 UCSF GRCh37 17 6329013 6329013 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 39 51 0 ENST00000381129.3:c.922C>T p.Leu308= p.L308= ENST00000381129 NM_014336.3 308 Ctg/Ttg 0 +AIRE UCSF GRCh37 21 45713770 45713770 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 9 23 0 ENST00000291582.5:c.1377C>T p.Phe459= p.F459= ENST00000291582 NM_000383.3 459 ttC/ttT 0 +AK8 UCSF GRCh37 9 135698602 135698602 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 160 79 156 0 ENST00000298545.3:c.879G>A p.Arg293= p.R293= ENST00000298545 NM_152572.2 293 agG/agA 0 +AKAP10 UCSF GRCh37 17 19823376 19823376 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 39 99 0 ENST00000225737.6:c.1807C>T p.Pro603Ser p.P603S ENST00000225737 NM_007202.3 603 Cct/Tct 0 +AKAP12 UCSF GRCh37 6 151673720 151673720 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 73 147 0 ENST00000402676.2:c.4194C>T p.Pro1398= p.P1398= ENST00000402676 NM_005100.3 1398 ccC/ccT 0 +AKAP12 UCSF GRCh37 6 151674666 151674666 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 90 166 0 ENST00000402676.2:c.5140C>T p.Leu1714= p.L1714= ENST00000402676 NM_005100.3 1714 Ctg/Ttg 0 +AKAP4 UCSF GRCh37 X 49957587 49957587 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 80 179 0 ENST00000358526.2:c.1777G>A p.Ala593Thr p.A593T ENST00000358526 NM_003886.2 593 Gcc/Acc 0 +AKAP8L UCSF GRCh37 19 15512078 15512078 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 74 119 0 ENST00000397410.5:c.699C>T p.Phe233= p.F233= ENST00000397410 NM_014371.2 233 ttC/ttT 0 +AKAP9 UCSF GRCh37 7 91622205 91622205 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 49 109 0 ENST00000356239.3:c.412G>A p.Glu138Lys p.E138K ENST00000356239 NM_147185.2 138 Gaa/Aaa 0 +AKNA UCSF GRCh37 9 117124707 117124707 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 16 43 0 ENST00000307564.4:c.1895C>T p.Pro632Leu p.P632L ENST00000307564 NM_030767.4 632 cCt/cTt 0 +AKR1B1 UCSF GRCh37 7 134136450 134136450 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 50 99 0 ENST00000285930.4:c.122G>A p.Arg41His p.R41H ENST00000285930 NM_001628.2 41 cGc/cAc 0 +AKR1C1 UCSF GRCh37 10 5011051 5011051 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 170 67 159 0 ENST00000380872.4:c.485C>T p.Ser162Phe p.S162F ENST00000380872 NM_001353.5 162 tCc/tTc 0 +ALAD UCSF GRCh37 9 116154398 116154398 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 16 41 0 ENST00000409155.3:c.164+1G>A p.X55_splice ENST00000409155 NM_000031.5 0 +ALDH3B2 UCSF GRCh37 11 67432886 67432886 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 28 159 0 ENST00000349015.3:c.576C>T p.Gly192= p.G192= ENST00000349015 NM_000695.3 192 ggC/ggT 0 +ALDH9A1 UCSF GRCh37 1 165636589 165636589 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 43 135 0 ENST00000354775.4:c.1306G>A p.Ala436Thr p.A436T ENST00000354775 NM_000696.3 436 Gcc/Acc 0 +ALG10 UCSF GRCh37 12 34179346 34179346 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 136 132 266 0 ENST00000266483.2:c.918C>T p.Leu306= p.L306= ENST00000266483 NM_032834.3 306 ctC/ctT 0 +ALKBH4 UCSF GRCh37 7 102098081 102098081 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 16 14 0 ENST00000292566.3:c.669G>A p.Arg223= p.R223= ENST00000292566 NM_017621.3 223 cgG/cgA 0 +ALMS1 UCSF GRCh37 2 73675671 73675671 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 103 194 0 ENST00000264448.6:c.2014G>A p.Glu672Lys p.E672K ENST00000264448 NM_015120.4 672 Gag/Aag 0 +ALOX15 UCSF GRCh37 17 4542415 4542415 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 74 151 0 ENST00000570836.1:c.350G>A p.Gly117Asp p.G117D ENST00000570836 117 gGc/gAc 0 +ALOX5AP UCSF GRCh37 13 31338144 31338144 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 88 196 0 ENST00000380490.3:c.387C>T p.Gly129= p.G129= ENST00000380490 NM_001629.3 129 ggC/ggT 0 +ALPK2 UCSF GRCh37 18 56202444 56202444 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 90 196 0 ENST00000361673.3:c.4975G>A p.Glu1659Lys p.E1659K ENST00000361673 NM_052947.3 1659 Gaa/Aaa 0 +ALPK2 UCSF GRCh37 18 56246635 56246635 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 92 188 0 ENST00000361673.3:c.1373C>T p.Ala458Val p.A458V ENST00000361673 NM_052947.3 458 gCt/gTt 0 +ALPK3 UCSF GRCh37 15 85383430 85383430 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 38 108 0 ENST00000258888.5:c.1526C>T p.Ala509Val p.A509V ENST00000258888 NM_020778.4 509 gCc/gTc 0 +ALPK3 UCSF GRCh37 15 85403012 85403012 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 34 42 0 ENST00000258888.5:c.4577G>A p.Gly1526Glu p.G1526E ENST00000258888 NM_020778.4 1526 gGg/gAg 0 +ALPP UCSF GRCh37 2 233245969 233245969 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 23 73 0 ENST00000392027.2:c.1201C>T p.Pro401Ser p.P401S ENST00000392027 NM_001632.3 401 Cct/Tct 0 +ALS2CL UCSF GRCh37 3 46724728 46724728 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 1 21 40 0 ENST00000318962.4:c.1001C>T p.Pro334Leu p.P334L ENST00000318962 NM_147129.3 334 cCc/cTc 0 +AMBN UCSF GRCh37 4 71467161 71467161 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 113 197 0 ENST00000322937.6:c.321C>T p.Pro107= p.P107= ENST00000322937 NM_016519.5 107 ccC/ccT 0 +AMBRA1 UCSF GRCh37 11 46563580 46563580 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 82 133 0 ENST00000314845.3:c.1717C>T p.Gln573Ter p.Q573* ENST00000314845 NM_017749.3 573 Cag/Tag 0 +AMMECR1L UCSF GRCh37 2 128628503 128628503 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 86 81 156 0 ENST00000272647.5:c.519-1G>A p.X173_splice ENST00000272647 NM_001199140.1 0 +AMOT UCSF GRCh37 X 112058905 112058905 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 23 26 0 ENST00000371959.3:c.1073C>T p.Pro358Leu p.P358L ENST00000371959 NM_001113490.1 358 cCt/cTt 0 +AMOT UCSF GRCh37 X 112065626 112065626 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 21 42 0 ENST00000371959.3:c.729C>T p.Pro243= p.P243= ENST00000371959 NM_001113490.1 243 ccC/ccT 0 +ANGEL1 UCSF GRCh37 14 77273075 77273075 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 105 179 0 ENST00000251089.2:c.1064G>A p.Gly355Asp p.G355D ENST00000251089 NM_015305.3 355 gGc/gAc 0 +ANGPTL6 UCSF GRCh37 19 10205520 10205520 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 48 82 0 ENST00000253109.4:c.677C>T p.Pro226Leu p.P226L ENST00000253109 NM_031917.2 226 cCc/cTc 0 +ANGPTL6 UCSF GRCh37 19 10204462 10204462 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 74 168 0 ENST00000253109.4:c.858G>A p.Trp286Ter p.W286* ENST00000253109 NM_031917.2 286 tgG/tgA 0 +ANGPTL6 UCSF GRCh37 19 10205450 10205450 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 76 150 1 ENST00000253109.4:c.747C>T p.Val249= p.V249= ENST00000253109 NM_031917.2 249 gtC/gtT 0 +ANK2 UCSF GRCh37 4 114257791 114257791 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 56 135 0 ENST00000357077.4:c.3650G>A p.Ser1217Asn p.S1217N ENST00000357077 NM_001148.4 1217 aGc/aAc 0 +ANK3 UCSF GRCh37 10 61834433 61834433 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 83 60 184 0 ENST00000280772.2:c.6206A>G p.Lys2069Arg p.K2069R ENST00000280772 NM_020987.3 2069 aAa/aGa 0 +ANKDD1A UCSF GRCh37 15 65214219 65214219 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 27 65 0 ENST00000380230.3:c.366+1G>A p.X122_splice ENST00000380230 NM_182703.3 0 +ANKHD1 UCSF GRCh37 5 139864786 139864786 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 47 99 0 ENST00000297183.6:c.1951G>A p.Val651Ile p.V651I ENST00000297183 NM_020690.5 651 Gtt/Att 0 +ANKHD1 UCSF GRCh37 5 139887397 139887397 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 55 140 0 ENST00000297183.6:c.3579C>T p.Pro1193= p.P1193= ENST00000297183 NM_020690.5 1193 ccC/ccT 0 +ANKLE2 UCSF GRCh37 12 133311100 133311100 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 94 198 0 ENST00000357997.5:c.1762G>A p.Val588Ile p.V588I ENST00000357997 NM_015114.1 588 Gtt/Att 0 +ANKLE2 UCSF GRCh37 12 133313506 133313506 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 69 106 0 ENST00000357997.5:c.1566C>T p.Ala522= p.A522= ENST00000357997 NM_015114.1 522 gcC/gcT 0 +ANKMY2 UCSF GRCh37 7 16655440 16655440 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 37 137 0 ENST00000306999.2:c.460C>T p.Pro154Ser p.P154S ENST00000306999 NM_020319.2 154 Cca/Tca 0 +ANKRD13B UCSF GRCh37 17 27936181 27936181 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 29 43 0 ENST00000394859.3:c.643G>A p.Asp215Asn p.D215N ENST00000394859 NM_152345.4 215 Gac/Aac 0 +ANKRD17 UCSF GRCh37 4 73956561 73956561 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 117 241 0 ENST00000358602.4:c.6784C>T p.Pro2262Ser p.P2262S ENST00000358602 NM_032217.3 2262 Cct/Tct 0 +ANKRD17 UCSF GRCh37 4 73964177 73964177 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 49 140 0 ENST00000358602.4:c.4634C>T p.Ser1545Phe p.S1545F ENST00000358602 NM_032217.3 1545 tCt/tTt 0 +ANKRD2 UCSF GRCh37 10 99338294 99338294 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 11 16 0 ENST00000307518.5:c.469G>A p.Val157Met p.V157M ENST00000307518 157 Gtg/Atg 0 +ANKRD20A1 UCSF GRCh37 9 67951934 67951934 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 37 211 0 ENST00000377477.2:c.897G>A p.Gln299= p.Q299= ENST00000377477 NM_032250.3 299 caG/caA 0 +ANKRD56 UCSF GRCh37 4 77817460 77817460 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 52 113 0 ENST00000334306.2:c.1543C>T p.Leu515Phe p.L515F ENST00000334306 NM_001029870.1 515 Ctc/Ttc 0 +ANKS6 UCSF GRCh37 9 101552469 101552469 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 100 51 114 0 ENST00000353234.4:c.779C>T p.Thr260Ile p.T260I ENST00000353234 260 aCc/aTc 0 +ANO10 UCSF GRCh37 3 43618310 43618310 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 51 130 0 ENST00000292246.3:c.1036C>T p.Leu346= p.L346= ENST00000292246 NM_018075.3 346 Cta/Tta 0 +ANO2 UCSF GRCh37 12 5939622 5939622 + synonymous_variant Silent SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 55 47 124 0 ENST00000327087.8:c.807T>C p.Asp269= p.D269= ENST00000327087 NM_001278596.1 269 gaT/gaC 0 +ANO3 UCSF GRCh37 11 26569093 26569093 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 88 200 0 ENST00000256737.3:c.1285G>A p.Val429Ile p.V429I ENST00000256737 NM_031418.2 429 Gta/Ata 0 +ANXA11 UCSF GRCh37 10 81929013 81929013 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 16 24 0 ENST00000438331.1:c.273G>A p.Gly91= p.G91= ENST00000438331 NM_145869.1 91 ggG/ggA 0 +AOX1 UCSF GRCh37 2 201515866 201515866 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 71 157 0 ENST00000374700.2:c.3017G>A p.Gly1006Glu p.G1006E ENST00000374700 NM_001159.3 1006 gGa/gAa 0 +AP2A1 UCSF GRCh37 19 50302723 50302723 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 36 75 0 ENST00000359032.5:c.1105C>T p.His369Tyr p.H369Y ENST00000359032 NM_014203.2 369 Cac/Tac 0 +AP3D1 UCSF GRCh37 19 2137026 2137026 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 8 18 0 ENST00000355272.6:c.338C>T p.Thr113Ile p.T113I ENST00000355272 NM_001261826.1 113 aCc/aTc 0 +APBB1IP UCSF GRCh37 10 26849663 26849663 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 180 84 156 0 ENST00000376236.4:c.1259G>A p.Gly420Glu p.G420E ENST00000376236 NM_019043.3 420 gGg/gAg 0 +APC UCSF GRCh37 5 112177281 112177281 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 77 82 154 0 ENST00000257430.4:c.5990G>A p.Gly1997Glu p.G1997E ENST00000257430 NM_000038.5 1997 gGa/gAa 0 +APC2 UCSF GRCh37 19 1455233 1455233 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 11 21 0 ENST00000535453.1:c.499G>A p.Asp167Asn p.D167N ENST00000535453 167 Gac/Aac 0 +APC2 UCSF GRCh37 19 1466048 1466048 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 13 13 0 ENST00000535453.1:c.2748G>A p.Lys916= p.K916= ENST00000535453 916 aaG/aaA 0 +APCDD1L UCSF GRCh37 20 57036226 57036226 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 45 71 0 ENST00000371149.3:c.1126C>T p.Pro376Ser p.P376S ENST00000371149 NM_153360.1 376 Cca/Tca 0 +API5 UCSF GRCh37 11 43350277 43350277 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 61 123 0 ENST00000531273.1:c.961C>T p.Pro321Ser p.P321S ENST00000531273 321 Cct/Tct 0 +APLP1 UCSF GRCh37 19 36365772 36365772 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 28 35 0 ENST00000221891.4:c.1344+1G>A p.X448_splice ENST00000221891 NM_001024807.1 0 +APOA1 UCSF GRCh37 11 116707873 116707873 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 40 90 0 ENST00000236850.4:c.44G>A p.Gly15Glu p.G15E ENST00000236850 NM_000039.1 15 gGg/gAg 0 +APOB UCSF GRCh37 2 21227277 21227277 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 60 145 0 ENST00000233242.1:c.11951C>T p.Thr3984Ile p.T3984I ENST00000233242 NM_000384.2 3984 aCc/aTc 0 +APOB UCSF GRCh37 2 21232067 21232067 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 105 175 0 ENST00000233242.1:c.7673C>T p.Ala2558Val p.A2558V ENST00000233242 NM_000384.2 2558 gCt/gTt 0 +APOB UCSF GRCh37 2 21232078 21232078 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 69 146 0 ENST00000233242.1:c.7662G>A p.Trp2554Ter p.W2554* ENST00000233242 NM_000384.2 2554 tgG/tgA 0 +APP UCSF GRCh37 21 27284207 27284207 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 53 121 0 ENST00000346798.3:c.1755G>A p.Arg585= p.R585= ENST00000346798 NM_000484.3 585 agG/agA 0 +AQP1 UCSF GRCh37 7 30963178 30963178 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 18 20 49 0 ENST00000311813.4:c.744C>T p.Gly248= p.G248= ENST00000311813 NM_198098.2 248 ggC/ggT 0 +AQP5 UCSF GRCh37 12 50358930 50358930 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 31 50 0 ENST00000293599.6:c.768G>A p.Arg256= p.R256= ENST00000293599 NM_001651.3 256 cgG/cgA 0 +AR UCSF GRCh37 X 66765407 66765407 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 6 14 0 ENST00000374690.3:c.419C>T p.Ala140Val p.A140V ENST00000374690 NM_000044.3 140 gCc/gTc 0 +AR UCSF GRCh37 X 66766136 66766136 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 13 30 0 ENST00000374690.3:c.1148C>T p.Pro383Leu p.P383L ENST00000374690 NM_000044.3 383 cCc/cTc 0 +ARAP2 UCSF GRCh37 4 36115845 36115845 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 124 112 201 0 ENST00000303965.4:c.4103C>T p.Pro1368Leu p.P1368L ENST00000303965 NM_015230.3 1368 cCt/cTt 0 +ARAP2 UCSF GRCh37 4 36212084 36212084 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 68 138 1 ENST00000303965.4:c.1415C>T p.Pro472Leu p.P472L ENST00000303965 NM_015230.3 472 cCc/cTc 0 +ARAP2 UCSF GRCh37 4 36109269 36109269 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 59 179 0 ENST00000303965.4:c.4203G>A p.Arg1401= p.R1401= ENST00000303965 NM_015230.3 1401 cgG/cgA 0 +ARAP3 UCSF GRCh37 5 141033734 141033734 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 40 104 0 ENST00000239440.4:c.4418G>A p.Ser1473Asn p.S1473N ENST00000239440 NM_022481.5 1473 aGc/aAc 0 +ARC UCSF GRCh37 8 143695255 143695255 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 7 25 0 ENST00000356613.2:c.378G>A p.Trp126Ter p.W126* ENST00000356613 NM_015193.4 126 tgG/tgA 0 +ARCN1 UCSF GRCh37 11 118454053 118454053 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 55 125 0 ENST00000264028.4:c.427G>A p.Val143Met p.V143M ENST00000264028 NM_001655.4 143 Gtg/Atg 0 +ARFGEF2 UCSF GRCh37 20 47582530 47582530 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 63 139 0 ENST00000371917.4:c.1029C>T p.Asp343= p.D343= ENST00000371917 NM_006420.2 343 gaC/gaT 0 +ARGLU1 UCSF GRCh37 13 107196384 107196384 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 56 72 0 ENST00000400198.3:c.782C>T p.Ser261Phe p.S261F ENST00000400198 NM_018011.3 261 tCc/tTc 0 +ARHGAP15 UCSF GRCh37 2 144193197 144193197 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 21 59 0 ENST00000295095.6:c.502C>T p.Leu168Phe p.L168F ENST00000295095 NM_018460.3 168 Ctt/Ttt 0 +ARHGAP22 UCSF GRCh37 10 49687707 49687707 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 25 34 0 ENST00000417912.2:c.423C>T p.Arg141= p.R141= ENST00000417912 141 cgC/cgT 0 +ARHGAP23 UCSF GRCh37 17 36623249 36623249 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 17 0 ENST00000431231.2:c.1325C>T p.Pro442Leu p.P442L ENST00000431231 NM_001199417.1 442 cCc/cTc 0 +ARHGAP31 UCSF GRCh37 3 119120774 119120774 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 47 99 0 ENST00000264245.4:c.1175C>T p.Thr392Ile p.T392I ENST00000264245 NM_020754.2 392 aCc/aTc 0 +ARHGAP33 UCSF GRCh37 19 36278595 36278595 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 40 68 0 ENST00000314737.5:c.2645C>T p.Pro882Leu p.P882L ENST00000314737 NM_052948.3 882 cCc/cTc 0 +ARHGAP9 UCSF GRCh37 12 57868745 57868745 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 30 80 0 ENST00000393791.3:c.1564G>A p.Gly522Ser p.G522S ENST00000393791 NM_032496.2 522 Ggc/Agc 0 +ARHGEF1 UCSF GRCh37 19 42392174 42392174 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 30 68 0 ENST00000337665.4:c.66G>A p.Gly22= p.G22= ENST00000337665 NM_199002.1 22 ggG/ggA 0 +ARHGEF10 UCSF GRCh37 8 1893800 1893800 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 46 118 0 ENST00000349830.3:c.3376C>T p.Pro1126Ser p.P1126S ENST00000349830 NM_014629.2 1126 Cct/Tct 0 +ARHGEF12 UCSF GRCh37 11 120345319 120345319 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 64 149 0 ENST00000397843.2:c.3084G>A p.Trp1028Ter p.W1028* ENST00000397843 NM_015313.2 1028 tgG/tgA 0 +ARHGEF16 UCSF GRCh37 1 3396387 3396387 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 28 68 0 ENST00000378378.4:c.1900G>A p.Val634Met p.V634M ENST00000378378 NM_014448.3 634 Gtg/Atg 0 +ARHGEF17 UCSF GRCh37 11 73073499 73073499 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 12 29 0 ENST00000263674.3:c.4716G>A p.Arg1572= p.R1572= ENST00000263674 NM_014786.3 1572 agG/agA 0 +ARHGEF18 UCSF GRCh37 19 7518385 7518385 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 71 172 0 ENST00000359920.6:c.1324G>A p.Ala442Thr p.A442T ENST00000359920 NM_001130955.1 442 Gcc/Acc 0 +ARHGEF37 UCSF GRCh37 5 149001611 149001611 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 16 42 0 ENST00000333677.6:c.1321G>A p.Gly441Arg p.G441R ENST00000333677 NM_001001669.2 441 Gga/Aga 0 +ARHGEF40 UCSF GRCh37 14 21542423 21542423 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 44 97 0 ENST00000298694.4:c.534G>A p.Trp178Ter p.W178* ENST00000298694 NM_001278529.1 178 tgG/tgA 0 +ARHGEF9 UCSF GRCh37 X 62858032 62858032 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 19 17 49 0 ENST00000253401.6:c.1427A>G p.Asn476Ser p.N476S ENST00000253401 NM_015185.2 476 aAc/aGc 0 +ARID1A UCSF GRCh37 1 27087438 27087438 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 90 85 168 0 ENST00000324856.7:c.2012G>A p.Gly671Glu p.G671E ENST00000324856 NM_006015.4 671 gGa/gAa 0 +ARID1A UCSF GRCh37 1 27106776 27106776 + synonymous_variant Silent SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 108 97 196 0 ENST00000324856.7:c.6387C>T p.Asp2129= p.D2129= ENST00000324856 NM_006015.4 2129 gaC/gaT 0 +ARID1B UCSF GRCh37 6 157405897 157405897 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 64 163 0 ENST00000346085.5:c.2139C>T p.Ser713= p.S713= ENST00000346085 NM_020732.3 713 agC/agT 0 +ARID2 UCSF GRCh37 12 46125022 46125022 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 59 140 0 ENST00000334344.6:c.209G>A p.Gly70Glu p.G70E ENST00000334344 NM_152641.2 70 gGa/gAa 0 +ARID3C UCSF GRCh37 9 34621480 34621480 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 20 40 0 ENST00000378909.2:c.1214G>A p.Gly405Glu p.G405E ENST00000378909 NM_001017363.1 405 gGg/gAg 0 +ARID4B UCSF GRCh37 1 235383229 235383229 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 49 140 0 ENST00000264183.3:c.1462G>A p.Glu488Lys p.E488K ENST00000264183 NM_016374.5 488 Gaa/Aaa 0 +ARID5B UCSF GRCh37 10 63852245 63852245 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 74 134 0 ENST00000279873.7:c.3023C>T p.Ala1008Val p.A1008V ENST00000279873 NM_032199.2 1008 gCg/gTg 0 +ARL4A UCSF GRCh37 7 12728445 12728445 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 152 119 240 0 ENST00000396663.1:c.566G>A p.Arg189Lys p.R189K ENST00000396663 NM_005738.4 189 aGa/aAa 0 +ARL8B UCSF GRCh37 3 5216037 5216037 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 70 134 0 ENST00000256496.3:c.449C>T p.Ser150Phe p.S150F ENST00000256496 NM_018184.2 150 tCt/tTt 0 +ARMC2 UCSF GRCh37 6 109225435 109225435 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 128 105 220 0 ENST00000392644.4:c.850G>A p.Glu284Lys p.E284K ENST00000392644 NM_032131.4 284 Gaa/Aaa 0 +ARMC4 UCSF GRCh37 10 28272880 28272880 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 130 56 143 0 ENST00000305242.5:c.711C>T p.Ala237= p.A237= ENST00000305242 NM_018076.2 237 gcC/gcT 0 +ARMC5 UCSF GRCh37 16 31473836 31473836 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 37 52 0 ENST00000268314.4:c.968G>A p.Gly323Asp p.G323D ENST00000268314 NM_001105247.1 323 gGc/gAc 0 +ARMCX5 UCSF GRCh37 X 101857164 101857164 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 65 160 0 ENST00000604957.1:c.95G>A p.Gly32Asp p.G32D ENST00000604957 NM_001168478.1 32 gGt/gAt 0 +ARNT2 UCSF GRCh37 15 80869262 80869262 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 77 182 0 ENST00000303329.4:c.1569C>T p.Ser523= p.S523= ENST00000303329 NM_014862.3 523 tcC/tcT 0 +ARPM1 UCSF GRCh37 3 169485867 169485867 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 54 129 0 ENST00000330368.2:c.472G>A p.Val158Ile p.V158I ENST00000330368 NM_032487.4 158 Gtt/Att 0 +ARRDC1 UCSF GRCh37 9 140508117 140508117 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 129 55 117 0 ENST00000371421.4:c.331G>A p.Val111Met p.V111M ENST00000371421 NM_152285.2 111 Gtg/Atg 0 +ARSA UCSF GRCh37 22 51065061 51065061 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 39 76 0 ENST00000216124.5:c.812G>A p.Gly271Glu p.G271E ENST00000216124 NM_000487.5 271 gGg/gAg 0 +ARSF UCSF GRCh37 X 3030361 3030361 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 84 218 0 ENST00000381127.1:c.1537C>T p.Pro513Ser p.P513S ENST00000381127 NM_001201539.1 513 Ccc/Tcc 0 +ARSJ UCSF GRCh37 4 114824812 114824812 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 72 159 1 ENST00000315366.7:c.418C>T p.Leu140Phe p.L140F ENST00000315366 NM_024590.3 140 Ctt/Ttt 0 +ART3 UCSF GRCh37 4 77003181 77003181 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 75 180 0 ENST00000355810.4:c.274G>A p.Asp92Asn p.D92N ENST00000355810 NM_001130016.2 92 Gat/Aat 0 +ART4 UCSF GRCh37 12 14982321 14982321 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 44 120 1 ENST00000228936.4:c.929C>T p.Ser310Phe p.S310F ENST00000228936 NM_021071.2 310 tCc/tTc 0 +ASB1 UCSF GRCh37 2 239344428 239344428 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 38 59 0 ENST00000264607.4:c.268C>T p.His90Tyr p.H90Y ENST00000264607 NM_001040445.1 90 Cat/Tat 0 +ASF1B UCSF GRCh37 19 14231375 14231375 + missense_variant Missense_Mutation SNP A A T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 18 31 0 ENST00000263382.3:c.505T>A p.Ser169Thr p.S169T ENST00000263382 NM_018154.2 169 Tcc/Acc 0 +ASH1L UCSF GRCh37 1 155451034 155451034 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 61 167 0 ENST00000392403.3:c.1627G>A p.Ala543Thr p.A543T ENST00000392403 NM_018489.2 543 Gct/Act 0 +ASH1L UCSF GRCh37 1 155449132 155449132 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 75 159 0 ENST00000392403.3:c.3529C>T p.Leu1177Phe p.L1177F ENST00000392403 NM_018489.2 1177 Ctc/Ttc 0 +ASL UCSF GRCh37 7 65551635 65551635 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 16 42 0 ENST00000304874.9:c.510C>T p.Ser170= p.S170= ENST00000304874 NM_000048.3 170 agC/agT 0 +ASPSCR1 UCSF GRCh37 17 79968702 79968702 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 25 55 1 ENST00000306729.7:c.1195G>A p.Asp399Asn p.D399N ENST00000306729 NM_001251888.1 399 Gac/Aac 0 +ASXL1 UCSF GRCh37 20 31022675 31022675 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 55 83 0 ENST00000375687.4:c.2160C>T p.Asp720= p.D720= ENST00000375687 NM_015338.5 720 gaC/gaT 0 +ASXL1 UCSF GRCh37 20 31023287 31023287 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 73 139 0 ENST00000375687.4:c.2772C>T p.Pro924= p.P924= ENST00000375687 NM_015338.5 924 ccC/ccT 0 +ATAD2 UCSF GRCh37 8 124384893 124384893 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P10_Rec Untested WXS Illumina HiSeq 46 0 ENST00000287394.5:c.354delA p.Glu119LysfsTer8 p.E119Kfs*8 ENST00000287394 NM_014109.3 118 aaA/aa 0 +ATAD2B UCSF GRCh37 2 24046250 24046250 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 138 95 188 0 ENST00000238789.5:c.2009C>T p.Ser670Phe p.S670F ENST00000238789 NM_001242338.1 670 tCt/tTt 0 +ATAD3C UCSF GRCh37 1 1394579 1394579 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 58 102 0 ENST00000378785.2:c.780C>T p.Ala260= p.A260= ENST00000378785 NM_001039211.2 260 gcC/gcT 0 +ATAD5 UCSF GRCh37 17 29196607 29196607 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 74 169 0 ENST00000321990.4:c.3550G>A p.Gly1184Ser p.G1184S ENST00000321990 NM_024857.3 1184 Ggt/Agt 0 +ATG13 UCSF GRCh37 11 46671819 46671819 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 112 202 0 ENST00000528494.1:c.410C>T p.Ala137Val p.A137V ENST00000528494 NM_001205119.1 137 gCc/gTc 0 +ATG2A UCSF GRCh37 11 64674276 64674276 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 29 44 0 ENST00000377264.3:c.2844G>A p.Gly948= p.G948= ENST00000377264 NM_015104.2 948 ggG/ggA 0 +ATG2B UCSF GRCh37 14 96800741 96800741 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 34 89 0 ENST00000359933.4:c.1021+1G>A p.X341_splice ENST00000359933 NM_018036.5 0 +ATG4A UCSF GRCh37 X 107380354 107380354 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 62 213 0 ENST00000372232.3:c.501G>A p.Leu167= p.L167= ENST00000372232 NM_052936.3 167 ttG/ttA 0 +ATG4C UCSF GRCh37 1 63307111 63307111 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 40 122 0 ENST00000317868.4:c.1102C>T p.Pro368Ser p.P368S ENST00000317868 NM_032852.3 368 Cct/Tct 0 +ATG7 UCSF GRCh37 3 11348535 11348535 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 90 163 0 ENST00000354449.3:c.333+1G>A p.X111_splice ENST00000354449 NM_006395.2 0 +ATL2 UCSF GRCh37 2 38546043 38546043 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 87 155 0 ENST00000378954.4:c.482G>A p.Arg161Lys p.R161K ENST00000378954 NM_001135673.1 161 aGa/aAa 0 +ATL2 UCSF GRCh37 2 38525577 38525577 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 139 126 226 0 ENST00000378954.4:c.1341G>A p.Gln447= p.Q447= ENST00000378954 NM_001135673.1 447 caG/caA 0 +ATP11B UCSF GRCh37 3 182575747 182575747 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 92 173 0 ENST00000323116.5:c.933G>A p.Trp311Ter p.W311* ENST00000323116 NM_014616.2 311 tgG/tgA 0 +ATP13A3 UCSF GRCh37 3 194168634 194168634 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 112 178 0 ENST00000439040.1:c.1255G>A p.Ala419Thr p.A419T ENST00000439040 419 Gca/Aca 0 +ATP1A4 UCSF GRCh37 1 160128843 160128843 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 73 135 0 ENST00000368081.4:c.577G>A p.Val193Met p.V193M ENST00000368081 NM_144699.3 193 Gtg/Atg 0 +ATP2A2 UCSF GRCh37 12 110784078 110784078 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 63 179 0 ENST00000539276.2:c.2932C>T p.Leu978Phe p.L978F ENST00000539276 978 Ctc/Ttc 0 +ATP2A2 UCSF GRCh37 12 110778552 110778552 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 72 110 0 ENST00000539276.2:c.1850G>A p.Gly617Asp p.G617D ENST00000539276 617 gGc/gAc 0 +ATP2B1 UCSF GRCh37 12 89997948 89997948 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 60 99 0 ENST00000428670.3:c.2618G>A p.Gly873Asp p.G873D ENST00000428670 873 gGc/gAc 0 +ATP2B3 UCSF GRCh37 X 152807193 152807193 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 47 90 0 ENST00000263519.4:c.473C>T p.Ala158Val p.A158V ENST00000263519 NM_001001344.2 158 gCt/gTt 0 +ATP2B4 UCSF GRCh37 1 203690419 203690419 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 60 128 0 ENST00000357681.5:c.2693C>T p.Ser898Phe p.S898F ENST00000357681 NM_001684.4 898 tCt/tTt 0 +ATP2C2 UCSF GRCh37 16 84482283 84482283 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 62 102 0 ENST00000262429.4:c.1648C>T p.Leu550Phe p.L550F ENST00000262429 NM_014861.2 550 Ctc/Ttc 0 +ATP2C2 UCSF GRCh37 16 84442047 84442047 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 31 80 0 ENST00000262429.4:c.364G>A p.Ala122Thr p.A122T ENST00000262429 NM_014861.2 122 Gcc/Acc 0 +ATP6AP2 UCSF GRCh37 X 40456585 40456585 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 58 144 0 ENST00000378438.4:c.385C>T p.Pro129Ser p.P129S ENST00000378438 NM_005765.2 129 Ccc/Tcc 0 +ATP6V0D1 UCSF GRCh37 16 67472557 67472557 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 88 178 0 ENST00000290949.3:c.930C>T p.Phe310= p.F310= ENST00000290949 NM_004691.4 310 ttC/ttT 0 +ATP6V0D2 UCSF GRCh37 8 87126101 87126101 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 156 54 110 0 ENST00000285393.3:c.294C>T p.Thr98= p.T98= ENST00000285393 NM_152565.1 98 acC/acT 0 +ATP6V1A UCSF GRCh37 3 113503577 113503577 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 63 117 0 ENST00000273398.3:c.461G>A p.Gly154Glu p.G154E ENST00000273398 NM_001690.3 154 gGa/gAa 0 +ATP6V1B1 UCSF GRCh37 2 71192158 71192158 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 37 76 0 ENST00000234396.4:c.1449G>A p.Lys483= p.K483= ENST00000234396 NM_001692.3 483 aaG/aaA 0 +ATP6V1G1 UCSF GRCh37 9 117350193 117350193 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 8 11 0 ENST00000374050.3:c.75C>T p.Ala25= p.A25= ENST00000374050 NM_004888.3 25 gcC/gcT 0 +ATP6V1G2 UCSF GRCh37 6 31513939 31513939 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 54 119 0 ENST00000303892.5:c.130G>A p.Val44Met p.V44M ENST00000303892 NM_138282.2 44 Gtg/Atg 0 +ATP7B UCSF GRCh37 13 52542627 52542627 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 78 136 0 ENST00000242839.4:c.1660G>A p.Ala554Thr p.A554T ENST00000242839 NM_000053.3 554 Gca/Aca 0 +ATP7B UCSF GRCh37 13 52520511 52520511 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 16 40 0 ENST00000242839.4:c.2969C>T p.Ala990Val p.A990V ENST00000242839 NM_000053.3 990 gCc/gTc 0 +ATP7B UCSF GRCh37 13 52548653 52548653 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 105 211 0 ENST00000242839.4:c.703C>T p.Pro235Ser p.P235S ENST00000242839 NM_000053.3 235 Cct/Tct 0 +ATP8A1 UCSF GRCh37 4 42487635 42487635 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 70 195 0 ENST00000381668.5:c.2202C>T p.Leu734= p.L734= ENST00000381668 NM_006095.2 734 ctC/ctT 0 +ATP8B4 UCSF GRCh37 15 50189676 50189676 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 128 220 0 ENST00000284509.6:c.2510G>A p.Gly837Glu p.G837E ENST00000284509 NM_024837.3 837 gGa/gAa 0 +ATP8B4 UCSF GRCh37 15 50273457 50273457 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 40 112 0 ENST00000284509.6:c.783G>A p.Lys261= p.K261= ENST00000284509 NM_024837.3 261 aaG/aaA 0 +ATP9A UCSF GRCh37 20 50245563 50245563 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 85 190 0 ENST00000338821.5:c.1717G>A p.Val573Ile p.V573I ENST00000338821 NM_006045.1 573 Gtc/Atc 0 +ATP9B UCSF GRCh37 18 77097371 77097371 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 34 92 0 ENST00000426216.2:c.2205G>A p.Leu735= p.L735= ENST00000426216 NM_198531.3 735 ctG/ctA 0 +ATPBD4 UCSF GRCh37 15 35814403 35814403 + intron_variant Intron SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 49 101 0 ENST00000256538.4:c.312+16072G>A *104* ENST00000256538 NM_080650.3 0 +ATR UCSF GRCh37 3 142279142 142279142 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 71 175 0 ENST00000350721.4:c.1504C>T p.Leu502= p.L502= ENST00000350721 NM_001184.3 502 Ctg/Ttg 0 +ATRN UCSF GRCh37 20 3553565 3553565 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 59 161 0 ENST00000262919.5:c.2059G>A p.Glu687Lys p.E687K ENST00000262919 NM_139321.2 687 Gaa/Aaa 0 +ATRX UCSF GRCh37 X 76814225 76814225 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 75 68 168 0 ENST00000373344.5:c.6419A>G p.Asn2140Ser p.N2140S ENST00000373344 NM_000489.3 2140 aAt/aGt 0 +ATXN3L UCSF GRCh37 X 13337642 13337642 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 107 228 0 ENST00000380622.2:c.412G>A p.Ala138Thr p.A138T ENST00000380622 NM_001135995.1 138 Gcg/Acg 0 +AUTS2 UCSF GRCh37 7 70254999 70254999 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 27 35 0 ENST00000342771.4:c.2797G>A p.Ala933Thr p.A933T ENST00000342771 NM_015570.2 933 Gcc/Acc 0 +AVL9 UCSF GRCh37 7 32598829 32598829 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 55 126 0 ENST00000318709.4:c.968C>T p.Ser323Phe p.S323F ENST00000318709 NM_015060.1 323 tCt/tTt 0 +AVL9 UCSF GRCh37 7 32598950 32598950 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 56 118 0 ENST00000318709.4:c.1089C>T p.Val363= p.V363= ENST00000318709 NM_015060.1 363 gtC/gtT 0 +AVPR1B UCSF GRCh37 1 206230814 206230814 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 20 47 0 ENST00000367126.4:c.947C>T p.Thr316Ile p.T316I ENST00000367126 NM_000707.3 316 aCc/aTc 0 +AXIN1 UCSF GRCh37 16 347811 347811 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 10 25 0 ENST00000262320.3:c.1695C>T p.Gly565= p.G565= ENST00000262320 NM_003502.3 565 ggC/ggT 0 +AXL UCSF GRCh37 19 41759510 41759510 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 20 52 0 ENST00000301178.4:c.1933C>T p.Pro645Ser p.P645S ENST00000301178 NM_021913.4 645 Ccc/Tcc 0 +B4GALNT4 UCSF GRCh37 11 375904 375904 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 1 17 27 0 ENST00000329962.6:c.1043C>T p.Pro348Leu p.P348L ENST00000329962 NM_178537.4 348 cCc/cTc 0 +B4GALT2 UCSF GRCh37 1 44447467 44447467 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 43 85 0 ENST00000309519.7:c.507C>T p.Thr169= p.T169= ENST00000309519 169 acC/acT 0 +BAG2 UCSF GRCh37 6 57048760 57048760 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 80 183 0 ENST00000370693.5:c.408G>A p.Met136Ile p.M136I ENST00000370693 NM_004282.3 136 atG/atA 0 +BAG2 UCSF GRCh37 6 57048888 57048888 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 63 152 0 ENST00000370693.5:c.536G>A p.Arg179Lys p.R179K ENST00000370693 NM_004282.3 179 aGa/aAa 0 +BAHD1 UCSF GRCh37 15 40758176 40758176 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 80 131 0 ENST00000416165.1:c.2190C>T p.Leu730= p.L730= ENST00000416165 NM_014952.3 730 ctC/ctT 0 +BAI1 UCSF GRCh37 8 143545905 143545905 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 8 17 0 ENST00000517894.1:c.346G>A p.Gly116Ser p.G116S ENST00000517894 116 Ggc/Agc 0 +BAIAP2L1 UCSF GRCh37 7 97935766 97935766 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 52 121 0 ENST00000005260.8:c.1226C>T p.Thr409Ile p.T409I ENST00000005260 NM_018842.4 409 aCc/aTc 0 +BAZ2B UCSF GRCh37 2 160287578 160287578 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 80 157 0 ENST00000392783.2:c.1990G>A p.Glu664Lys p.E664K ENST00000392783 NM_013450.2 664 Gaa/Aaa 0 +BBS1 UCSF GRCh37 11 66283022 66283022 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 54 134 0 ENST00000318312.7:c.444C>T p.Asp148= p.D148= ENST00000318312 NM_024649.4 148 gaC/gaT 0 +BBS12 UCSF GRCh37 4 123663752 123663752 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 82 214 0 ENST00000542236.1:c.705G>A p.Arg235= p.R235= ENST00000542236 NM_001178007.1 235 agG/agA 0 +BBS4 UCSF GRCh37 15 73009191 73009191 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 16 46 0 ENST00000268057.4:c.405G>A p.Trp135Ter p.W135* ENST00000268057 NM_033028.4 135 tgG/tgA 0 +BCAS1 UCSF GRCh37 20 52645014 52645014 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 116 104 205 0 ENST00000395961.3:c.640G>A p.Glu214Lys p.E214K ENST00000395961 NM_003657.2 214 Gaa/Aaa 0 +BCL11A UCSF GRCh37 2 60679739 60679739 + downstream_gene_variant 3'Flank SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 68 126 0 ENST00000335712 NM_022893.3 0 +BCL11A UCSF GRCh37 2 60773220 60773220 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 84 188 0 ENST00000335712.6:c.271G>A p.Glu91Lys p.E91K ENST00000335712 NM_022893.3 91 Gag/Aag 0 +BCL11B UCSF GRCh37 14 99697883 99697883 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 11 0 ENST00000357195.3:c.439C>T p.Pro147Ser p.P147S ENST00000357195 NM_138576.2 147 Cct/Tct 0 +BCL2L11 UCSF GRCh37 2 111907635 111907635 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 31 72 0 ENST00000393256.3:c.409G>A p.Ala137Thr p.A137T ENST00000393256 NM_006538.4 137 Gct/Act 0 +BCL3 UCSF GRCh37 19 45260369 45260369 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 12 15 0 ENST00000164227.5:c.615C>T p.Gly205= p.G205= ENST00000164227 NM_005178.4 205 ggC/ggT 0 +BCOR UCSF GRCh37 X 39932533 39932533 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 53 81 0 ENST00000378444.4:c.2066G>A p.Gly689Asp p.G689D ENST00000378444 NM_001123385.1 689 gGc/gAc 0 +BCORL1 UCSF GRCh37 X 129171444 129171444 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 57 128 0 ENST00000540052.1:c.4408G>A p.Asp1470Asn p.D1470N ENST00000540052 NM_021946.4 1470 Gac/Aac 0 +BEAN1 UCSF GRCh37 16 66514512 66514512 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 19 24 0 ENST00000536005.2:c.464G>A p.Gly155Glu p.G155E ENST00000536005 NM_001178020.2 155 gGg/gAg 0 +BEST1 UCSF GRCh37 11 61724400 61724400 + missense_variant Missense_Mutation SNP C C T snp132_rs62639357 P10_Rec Untested WXS Illumina HiSeq 118 86 163 0 ENST00000449131.2:c.386C>T p.Ala129Val p.A129V ENST00000449131 NM_001139443.1 129 gCc/gTc 0 +BEST1 UCSF GRCh37 11 61730351 61730351 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 55 140 0 ENST00000449131.2:c.1545G>A p.Trp515Ter p.W515* ENST00000449131 NM_001139443.1 515 tgG/tgA 0 +BIN2 UCSF GRCh37 12 51696470 51696470 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 75 167 0 ENST00000267012.4:c.312G>A p.Trp104Ter p.W104* ENST00000267012 NM_016293.2 104 tgG/tgA 0 +BIN3 UCSF GRCh37 8 22479058 22479058 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 35 105 0 ENST00000276416.6:c.639C>T p.His213= p.H213= ENST00000276416 NM_018688.4 213 caC/caT 0 +BIRC6 UCSF GRCh37 2 32824908 32824908 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 85 209 0 ENST00000421745.2:c.13933C>T p.Leu4645= p.L4645= ENST00000421745 NM_016252.3 4645 Cta/Tta 0 +BIRC7 UCSF GRCh37 20 61870934 61870934 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 25 24 0 ENST00000217169.3:c.874C>T p.Arg292Cys p.R292C ENST00000217169 NM_139317.2 292 Cgc/Tgc 0 +BIRC7 UCSF GRCh37 20 61869332 61869332 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 17 38 0 ENST00000217169.3:c.427G>A p.Glu143Lys p.E143K ENST00000217169 NM_139317.2 143 Gag/Aag 0 +BIVM UCSF GRCh37 13 103474475 103474475 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 45 136 0 ENST00000257336.1:c.867G>A p.Lys289= p.K289= ENST00000257336 NM_017693.3 289 aaG/aaA 0 +BLNK UCSF GRCh37 10 98002540 98002540 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 46 125 0 ENST00000224337.5:c.114G>A p.Lys38= p.K38= ENST00000224337 NM_013314.3 38 aaG/aaA 0 +BLVRA UCSF GRCh37 7 43840116 43840116 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 38 80 0 ENST00000402924.1:c.405C>T p.Phe135= p.F135= ENST00000402924 NM_001253823.1 135 ttC/ttT 0 +BMP1 UCSF GRCh37 8 22058659 22058659 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 45 99 0 ENST00000306385.5:c.2108-657G>A *703* ENST00000306385 NM_006129.4 0 +BMP15 UCSF GRCh37 X 50659331 50659331 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 69 165 0 ENST00000252677.3:c.903C>T p.Arg301= p.R301= ENST00000252677 NM_005448.2 301 cgC/cgT 0 +BMPER UCSF GRCh37 7 33976972 33976972 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 41 105 0 ENST00000297161.2:c.291G>A p.Gln97= p.Q97= ENST00000297161 NM_133468.4 97 caG/caA 0 +BNC1 UCSF GRCh37 15 83932486 83932486 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 56 143 0 ENST00000345382.2:c.1517G>A p.Gly506Glu p.G506E ENST00000345382 NM_001717.3 506 gGg/gAg 0 +BNC1 UCSF GRCh37 15 83932013 83932013 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 79 151 0 ENST00000345382.2:c.1990C>T p.Pro664Ser p.P664S ENST00000345382 NM_001717.3 664 Ccc/Tcc 0 +BNIP2 UCSF GRCh37 15 59970244 59970244 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 105 221 0 ENST00000267859.3:c.701G>A p.Gly234Asp p.G234D ENST00000267859 234 gGc/gAc 0 +BOD1L UCSF GRCh37 4 13604919 13604919 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 134 126 202 0 ENST00000040738.5:c.3605C>T p.Thr1202Ile p.T1202I ENST00000040738 NM_148894.2 1202 aCc/aTc 0 +BOP1 UCSF GRCh37 8 145512976 145512976 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 105 24 61 0 ENST00000307404.5:c.109C>T p.Leu37Phe p.L37F ENST00000307404 NM_015201.3 37 Ctc/Ttc 0 +BPGM UCSF GRCh37 7 134346447 134346447 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 68 126 0 ENST00000393132.2:c.188C>T p.Ser63Phe p.S63F ENST00000393132 NM_199186.2 63 tCc/tTc 0 +BRAT1 UCSF GRCh37 7 2587021 2587021 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 40 66 0 ENST00000340611.4:c.219C>T p.Leu73= p.L73= ENST00000340611 NM_152743.3 73 ctC/ctT 0 +BRCA1 UCSF GRCh37 17 41201137 41201137 + splice_donor_variant Splice_Site SNP C C T snp132_rs80358028 P10_Rec somatic WXS Sanger Illumina HiSeq 50 39 83 0 ENST00000357654.3:c.5406+1G>A p.X1802_splice ENST00000357654 NM_007294.3 0 +BRD2 UCSF GRCh37 6 32945348 32945348 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 87 187 0 ENST00000395289.2:c.1329+1G>A p.X443_splice ENST00000395289 0 +BRD2 UCSF GRCh37 6 32947668 32947668 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 39 126 0 ENST00000395289.2:c.2010G>A p.Glu670= p.E670= ENST00000395289 670 gaG/gaA 0 +BRD3 UCSF GRCh37 9 136917491 136917491 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 119 50 117 0 ENST00000303407.7:c.288G>A p.Trp96Ter p.W96* ENST00000303407 NM_007371.3 96 tgG/tgA 0 +BRD8 UCSF GRCh37 5 137513329 137513329 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 83 133 0 ENST00000254900.5:c.47C>T p.Thr16Ile p.T16I ENST00000254900 NM_139199.1 16 aCa/aTa 0 +BRF2 UCSF GRCh37 8 37707147 37707147 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 33 72 0 ENST00000220659.6:c.154+1G>A p.X52_splice ENST00000220659 NM_018310.3 0 +BRPF1 UCSF GRCh37 3 9782593 9782593 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 38 103 0 ENST00000383829.2:c.1690C>T p.Leu564= p.L564= ENST00000383829 NM_001003694.1 564 Ctg/Ttg 0 +BRPF3 UCSF GRCh37 6 36169066 36169066 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 32 90 0 ENST00000357641.6:c.967C>T p.Leu323= p.L323= ENST00000357641 NM_015695.2 323 Cta/Tta 0 +BRWD1 UCSF GRCh37 21 40670433 40670433 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 76 186 0 ENST00000333229.2:c.274G>A p.Glu92Lys p.E92K ENST00000333229 NM_018963.4 92 Gaa/Aaa 0 +BSN UCSF GRCh37 3 49680186 49680186 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 41 74 0 ENST00000296452.4:c.1119C>T p.Thr373= p.T373= ENST00000296452 NM_003458.3 373 acC/acT 0 +BTBD2 UCSF GRCh37 19 1987249 1987249 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 18 61 0 ENST00000255608.4:c.1185C>T p.Phe395= p.F395= ENST00000255608 NM_017797.3 395 ttC/ttT 0 +BTN2A2 UCSF GRCh37 6 26390245 26390245 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 51 171 0 ENST00000356709.4:c.737C>T p.Pro246Leu p.P246L ENST00000356709 NM_001197240.1 246 cCc/cTc 0 +BTNL8 UCSF GRCh37 5 180376251 180376251 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 44 122 0 ENST00000340184.4:c.848C>T p.Ala283Val p.A283V ENST00000340184 NM_001040462.2 283 gCc/gTc 0 +BTNL8 UCSF GRCh37 5 180375366 180375366 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 145 125 273 0 ENST00000340184.4:c.799G>A p.Ala267Thr p.A267T ENST00000340184 NM_001040462.2 267 Gcg/Acg 0 +C10orf120 UCSF GRCh37 10 124459232 124459232 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 64 155 0 ENST00000329446.4:c.75G>A p.Arg25= p.R25= ENST00000329446 NM_001010912.2 25 agG/agA 0 +C11orf30 UCSF GRCh37 11 76234205 76234205 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 102 214 0 ENST00000529032.1:c.1691C>T p.Thr564Ile p.T564I ENST00000529032 564 aCt/aTt 0 +C11orf31 UCSF GRCh37 11 57509417 57509417 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 26 49 0 ENST00000388857.4:c.259G>A p.Asp87Asn p.D87N ENST00000388857 87 Gac/Aac 0 +C11orf88 UCSF GRCh37 11 111386773 111386773 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 61 152 0 ENST00000332814.6:c.277G>A p.Asp93Asn p.D93N ENST00000332814 NM_207430.2 93 Gac/Aac 0 +C11orf9 UCSF GRCh37 11 61550970 61550970 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 77 168 0 ENST00000278836.5:c.3017C>T p.Ala1006Val p.A1006V ENST00000278836 NM_001127392.1 1006 gCc/gTc 0 +C12orf34 UCSF GRCh37 12 110206997 110206997 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 16 24 0 ENST00000538780.1:c.1263C>T p.Ile421= p.I421= ENST00000538780 NM_032829.2 421 atC/atT 0 +C12orf48 UCSF GRCh37 12 102542198 102542198 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 93 144 0 ENST00000358383.5:c.344G>A p.Arg115Lys p.R115K ENST00000358383 115 aGg/aAg 0 +C12orf54 UCSF GRCh37 12 48888711 48888711 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 74 166 0 ENST00000314014.2:c.373C>T p.Pro125Ser p.P125S ENST00000314014 NM_152319.3 125 Cct/Tct 0 +C12orf54 UCSF GRCh37 12 48886731 48886731 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 29 84 0 ENST00000314014.2:c.195G>A p.Gly65= p.G65= ENST00000314014 NM_152319.3 65 ggG/ggA 0 +C14orf159 UCSF GRCh37 14 91671083 91671083 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 22 56 0 ENST00000518868.1:c.1478G>A p.Gly493Asp p.G493D ENST00000518868 NM_001286470.1 493 gGt/gAt 0 +C14orf159 UCSF GRCh37 14 91691107 91691107 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 27 52 0 ENST00000518868.1:c.1796G>A p.Gly599Glu p.G599E ENST00000518868 NM_001286470.1 599 gGg/gAg 0 +C14orf38 UCSF GRCh37 14 60027919 60027919 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 58 122 0 ENST00000537690.2:c.871G>A p.Ala291Thr p.A291T ENST00000537690 NM_001164399.1 291 Gca/Aca 0 +C14orf49 UCSF GRCh37 14 95921754 95921754 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 39 49 0 ENST00000334258.5:c.1097G>A p.Gly366Glu p.G366E ENST00000334258 NM_152592.3 366 gGg/gAg 0 +C15orf23 UCSF GRCh37 15 40683693 40683693 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 47 125 0 ENST00000249776.8:c.686-1G>A p.X229_splice ENST00000249776 NM_033286.3 0 +C15orf33 UCSF GRCh37 15 49659753 49659753 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 50 138 0 ENST00000299338.6:c.1163G>A p.Gly388Glu p.G388E ENST00000299338 NM_152647.2 388 gGa/gAa 0 +C15orf40 UCSF GRCh37 15 83677377 83677377 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 72 162 0 ENST00000451195.3:c.289G>A p.Gly97Arg p.G97R ENST00000451195 NM_001160115.1 97 Gga/Aga 0 +C15orf42 UCSF GRCh37 15 90167242 90167242 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 97 180 0 ENST00000268138.7:c.3701C>T p.Ala1234Val p.A1234V ENST00000268138 1234 gCc/gTc 0 +C15orf42 UCSF GRCh37 15 90119379 90119379 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 30 66 0 ENST00000268138.7:c.562G>A p.Val188Met p.V188M ENST00000268138 188 Gtg/Atg 0 +C16orf3 UCSF GRCh37 16 90095702 90095702 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 29 69 0 ENST00000408886.2:c.49C>T p.Pro17Ser p.P17S ENST00000408886 NM_001214.3 17 Ccc/Tcc 0 +C16orf48 UCSF GRCh37 16 67698965 67698965 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 56 148 0 ENST00000243878.4:c.387C>T p.Pro129= p.P129= ENST00000243878 NM_032140.1 129 ccC/ccT 0 +C17orf104 UCSF GRCh37 17 42743859 42743859 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 110 244 0 ENST00000409122.2:c.580G>A p.Ala194Thr p.A194T ENST00000409122 NM_001145080.2 194 Gct/Act 0 +C17orf47 UCSF GRCh37 17 56620740 56620740 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 107 214 0 ENST00000321691.3:c.808G>A p.Asp270Asn p.D270N ENST00000321691 NM_001038704.2 270 Gac/Aac 0 +C17orf63 UCSF GRCh37 17 27086333 27086333 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 12 40 0 ENST00000341217.5:c.644C>T p.Ala215Val p.A215V ENST00000341217 NM_001288633.1 215 gCt/gTt 0 +C17orf87 UCSF GRCh37 17 5114220 5114220 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 56 114 0 ENST00000574081.1:c.314C>T p.Ala105Val p.A105V ENST00000574081 NM_001271842.1 105 gCt/gTt 0 +C17orf87 UCSF GRCh37 17 5126707 5126707 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 49 211 0 ENST00000574081.1:c.66C>T p.Ile22= p.I22= ENST00000574081 NM_001271842.1 22 atC/atT 0 +C18orf45 UCSF GRCh37 18 20878020 20878020 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 37 75 0 ENST00000383233.3:c.842G>A p.Gly281Asp p.G281D ENST00000383233 NM_032933.4 281 gGt/gAt 0 +C19orf12 UCSF GRCh37 19 30199172 30199172 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 59 128 0 ENST00000392278.2:c.182G>A p.Gly61Glu p.G61E ENST00000392278 NM_001031726.3 61 gGa/gAa 0 +C19orf21 UCSF GRCh37 19 758600 758600 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 47 74 0 ENST00000215582.6:c.1654G>A p.Glu552Lys p.E552K ENST00000215582 NM_173481.2 552 Gag/Aag 0 +C19orf22 UCSF GRCh37 19 902122 902122 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 26 69 0 ENST00000361574.5:c.80C>T p.Pro27Leu p.P27L ENST00000361574 NM_138774.3 27 cCc/cTc 0 +C19orf44 UCSF GRCh37 19 16625456 16625456 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 11 22 0 ENST00000221671.3:c.1884C>T p.Thr628= p.T628= ENST00000221671 NM_032207.2 628 acC/acT 0 +C1orf227 UCSF GRCh37 1 213009442 213009442 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 78 204 0 ENST00000332912.3:c.50G>A p.Ser17Asn p.S17N ENST00000332912 NM_001024601.2 17 aGc/aAc 0 +C1orf27 UCSF GRCh37 1 186349002 186349002 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 76 191 0 ENST00000287859.6:c.85C>T p.Leu29Phe p.L29F ENST00000287859 NM_017847.5 29 Ctt/Ttt 0 +C1orf53 UCSF GRCh37 1 197874934 197874934 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 98 95 175 0 ENST00000367393.3:c.273G>A p.Gln91= p.Q91= ENST00000367393 NM_001024594.2 91 caG/caA 0 +C1orf85 UCSF GRCh37 1 156264741 156264741 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 46 96 0 ENST00000362007.1:c.187G>A p.Gly63Ser p.G63S ENST00000362007 NM_001256609.1 63 Ggc/Agc 0 +C1orf87 UCSF GRCh37 1 60505833 60505833 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 77 151 0 ENST00000371201.3:c.503G>A p.Ser168Asn p.S168N ENST00000371201 NM_152377.2 168 aGt/aAt 0 +C1QA UCSF GRCh37 1 22964259 22964259 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 23 1 ENST00000374642.3:c.150G>A p.Glu50= p.E50= ENST00000374642 NM_015991.2 50 gaG/gaA 0 +C1QTNF1 UCSF GRCh37 17 77042661 77042661 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 81 127 0 ENST00000339142.2:c.180C>T p.Tyr60= p.Y60= ENST00000339142 NM_198593.3 60 taC/taT 0 +C1QTNF5 UCSF GRCh37 11 119210158 119210158 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 53 106 0 ENST00000445041.2:c.615G>A p.Val205= p.V205= ENST00000445041 NM_031433.3 205 gtG/gtA 0 +C1R UCSF GRCh37 12 7242704 7242704 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 46 104 0 ENST00000542285.1:c.369G>A p.Glu123= p.E123= ENST00000542285 123 gaG/gaA 0 +C20orf103 UCSF GRCh37 20 9496254 9496254 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 90 162 0 ENST00000246070.2:c.219G>A p.Trp73Ter p.W73* ENST00000246070 NM_012261.3 73 tgG/tgA 0 +C20orf165 UCSF GRCh37 20 44515234 44515234 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 73 133 0 ENST00000372519.3:c.606G>A p.Gln202= p.Q202= ENST00000372519 NM_080608.3 202 caG/caA 0 +C20orf26 UCSF GRCh37 20 20177327 20177327 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 137 141 215 0 ENST00000245957.5:c.1704G>A p.Arg568= p.R568= ENST00000245957 NM_015585.3 568 cgG/cgA 0 +C20orf43 UCSF GRCh37 20 55052172 55052172 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 47 69 0 ENST00000023939.4:c.390C>T p.Gly130= p.G130= ENST00000023939 NM_016407.3 130 ggC/ggT 0 +C21orf62 UCSF GRCh37 21 34166277 34166277 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 60 108 0 ENST00000536776.1:c.456G>A p.Glu152= p.E152= ENST00000536776 NM_019596.5 152 gaG/gaA 0 +C22orf29 UCSF GRCh37 22 19839078 19839078 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 63 121 0 ENST00000405640.1:c.707C>T p.Ala236Val p.A236V ENST00000405640 236 gCc/gTc 0 +C2orf49 UCSF GRCh37 2 105959619 105959619 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 55 146 0 ENST00000258457.2:c.581C>T p.Pro194Leu p.P194L ENST00000258457 194 cCt/cTt 0 +C2orf53 UCSF GRCh37 2 27360284 27360284 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 36 76 0 ENST00000335524.3:c.914G>A p.Gly305Asp p.G305D ENST00000335524 NM_178553.3 305 gGc/gAc 0 +C2orf78 UCSF GRCh37 2 74041181 74041181 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 134 109 249 0 ENST00000409561.1:c.675C>T p.Cys225= p.C225= ENST00000409561 NM_001080474.1 225 tgC/tgT 0 +C2orf80 UCSF GRCh37 2 209046029 209046029 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 44 132 0 ENST00000341287.4:c.207G>A p.Leu69= p.L69= ENST00000341287 NM_001099334.2 69 ctG/ctA 0 +C3orf20 UCSF GRCh37 3 14768455 14768455 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 60 113 0 ENST00000253697.3:c.1614C>T p.Ser538= p.S538= ENST00000253697 NM_032137.4 538 agC/agT 0 +C3orf77 UCSF GRCh37 3 44312208 44312208 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 52 117 0 ENST00000309765.4:c.3278C>T p.Pro1093Leu p.P1093L ENST00000309765 NM_001145030.1 1093 cCc/cTc 0 +C5 UCSF GRCh37 9 123785682 123785682 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 250 125 231 0 ENST00000223642.1:c.1116G>A p.Lys372= p.K372= ENST00000223642 NM_001735.2 372 aaG/aaA 0 +C6orf162 UCSF GRCh37 6 88046815 88046815 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 65 160 0 ENST00000392863.1:c.66C>T p.Ser22= p.S22= ENST00000392863 NM_001042493.1 22 agC/agT 0 +C6orf211 UCSF GRCh37 6 151775763 151775763 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 50 138 0 ENST00000367294.3:c.122G>A p.Ser41Asn p.S41N ENST00000367294 NM_024573.1 41 aGt/aAt 0 +C6orf26 UCSF GRCh37 6 31732246 31732246 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 34 101 0 ENST00000415669.2:c.475C>T p.Pro159Ser p.P159S ENST00000415669 NM_001039651.1 159 Cca/Tca 0 +C6orf97 UCSF GRCh37 6 151917610 151917610 + synonymous_variant Silent SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 74 74 154 0 ENST00000239374.7:c.1608G>A p.Arg536= p.R536= ENST00000239374 NM_025059.3 536 agG/agA 0 +C6orf97 UCSF GRCh37 6 151907095 151907095 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 25 79 0 ENST00000239374.7:c.1164G>A p.Gln388= p.Q388= ENST00000239374 NM_025059.3 388 caG/caA 0 +C7orf25 UCSF GRCh37 7 42950222 42950222 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 120 114 200 0 ENST00000431882.2:c.452G>A p.Gly151Asp p.G151D ENST00000431882 151 gGt/gAt 0 +C8B UCSF GRCh37 1 57399066 57399066 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 112 0 ENST00000371237.4:c.1494G>A p.Lys498= p.K498= ENST00000371237 NM_000066.3 498 aaG/aaA 0 +C8orf58 UCSF GRCh37 8 22459558 22459558 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 13 16 0 ENST00000289989.5:c.731G>A p.Gly244Glu p.G244E ENST00000289989 244 gGg/gAg 0 +C9orf172 UCSF GRCh37 9 139741661 139741661 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 13 11 0 ENST00000436881.1:c.2795G>A p.Arg932Lys p.R932K ENST00000436881 NM_001080482.2 932 aGg/aAg 0 +C9orf172 UCSF GRCh37 9 139739794 139739794 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 42 22 46 0 ENST00000436881.1:c.928T>C p.Tyr310His p.Y310H ENST00000436881 NM_001080482.2 310 Tat/Cat 0 +C9orf79 UCSF GRCh37 9 90499973 90499973 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 161 64 124 0 ENST00000325643.5:c.571C>T p.Pro191Ser p.P191S ENST00000325643 NM_178828.4 191 Cca/Tca 0 +C9orf79 UCSF GRCh37 9 90500779 90500779 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 201 106 183 0 ENST00000325643.5:c.1377G>A p.Arg459= p.R459= ENST00000325643 NM_178828.4 459 agG/agA 0 +C9orf86 UCSF GRCh37 9 139726289 139726289 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 33 63 0 ENST00000371663.4:c.575G>A p.Arg192His p.R192H ENST00000371663 NM_001173988.1 192 cGt/cAt 0 +C9orf96 UCSF GRCh37 9 136268843 136268843 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 17 54 0 ENST00000371957.3:c.1494C>T p.Ala498= p.A498= ENST00000371957 NM_153710.4 498 gcC/gcT 0 +CA11 UCSF GRCh37 19 49143459 49143459 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 37 92 0 ENST00000084798.4:c.364G>A p.Gly122Ser p.G122S ENST00000084798 NM_001217.3 122 Ggt/Agt 0 +CA2 UCSF GRCh37 8 86377684 86377684 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 43 99 0 ENST00000285379.5:c.218C>T p.Ser73Phe p.S73F ENST00000285379 NM_000067.2 73 tCt/tTt 0 +CA8 UCSF GRCh37 8 61135318 61135318 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 44 100 0 ENST00000317995.4:c.628C>T p.Pro210Ser p.P210S ENST00000317995 NM_004056.4 210 Cct/Tct 0 +CACNA1B UCSF GRCh37 9 141015928 141015928 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 20 39 0 ENST00000371372.1:c.6497G>A p.Gly2166Asp p.G2166D ENST00000371372 NM_001243812.1 2166 gGt/gAt 0 +CACNA1B UCSF GRCh37 9 140811871 140811871 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 178 77 151 0 ENST00000371372.1:c.954C>T p.Asp318= p.D318= ENST00000371372 NM_001243812.1 318 gaC/gaT 0 +CACNA1B UCSF GRCh37 9 141012494 141012494 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 29 49 0 ENST00000371372.1:c.5874C>T p.Gly1958= p.G1958= ENST00000371372 NM_001243812.1 1958 ggC/ggT 0 +CACNA1C UCSF GRCh37 12 2614007 2614007 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 69 134 0 ENST00000347598.4:c.1114-1G>A p.X372_splice ENST00000347598 NM_199460.2 0 +CACNA1C UCSF GRCh37 12 2675744 2675744 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 32 55 0 ENST00000347598.4:c.1665C>T p.Val555= p.V555= ENST00000347598 NM_199460.2 555 gtC/gtT 0 +CACNA1H UCSF GRCh37 16 1260652 1260652 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 37 49 0 ENST00000348261.5:c.4038+1G>A p.X1346_splice ENST00000348261 NM_021098.2 0 +CACNA2D2 UCSF GRCh37 3 50404048 50404048 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 23 52 0 ENST00000479441.1:c.2619C>T p.Pro873= p.P873= ENST00000479441 873 ccC/ccT 0 +CACNA2D3 UCSF GRCh37 3 54880479 54880479 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 50 126 0 ENST00000474759.1:c.1611G>A p.Pro537= p.P537= ENST00000474759 NM_018398.2 537 ccG/ccA 0 +CACNA2D4 UCSF GRCh37 12 1910226 1910226 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 28 56 0 ENST00000382722.5:c.2851G>A p.Ala951Thr p.A951T ENST00000382722 NM_172364.4 951 Gcc/Acc 0 +CACNA2D4 UCSF GRCh37 12 2022207 2022207 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 57 131 1 ENST00000382722.5:c.408G>A p.Arg136= p.R136= ENST00000382722 NM_172364.4 136 agG/agA 0 +CADM1 UCSF GRCh37 11 115109292 115109292 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 73 143 0 ENST00000452722.3:c.352G>A p.Asp118Asn p.D118N ENST00000452722 NM_014333.3 118 Gat/Aat 0 +CADPS2 UCSF GRCh37 7 122377008 122377008 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 63 178 0 ENST00000449022.2:c.453+1G>A p.X151_splice ENST00000449022 NM_017954.10 0 +CADPS2 UCSF GRCh37 7 122303612 122303612 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 76 183 0 ENST00000449022.2:c.465G>A p.Lys155= p.K155= ENST00000449022 NM_017954.10 155 aaG/aaA 0 +CADPS2 UCSF GRCh37 7 122377060 122377060 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 63 157 0 ENST00000449022.2:c.402C>T p.Thr134= p.T134= ENST00000449022 NM_017954.10 134 acC/acT 0 +CALCB UCSF GRCh37 11 15098966 15098966 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 36 97 0 ENST00000533448.1:c.359G>A p.Arg120Lys p.R120K ENST00000533448 120 aGg/aAg 0 +CAMKK2 UCSF GRCh37 12 121687675 121687675 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 40 130 0 ENST00000324774.5:c.1238C>T p.Pro413Leu p.P413L ENST00000324774 NM_006549.3 413 cCc/cTc 0 +CAMKK2 UCSF GRCh37 12 121711908 121711908 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 10 13 0 ENST00000324774.5:c.422C>T p.Pro141Leu p.P141L ENST00000324774 NM_006549.3 141 cCc/cTc 0 +CAMTA2 UCSF GRCh37 17 4876206 4876206 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 64 100 0 ENST00000414043.3:c.2430C>T p.Asp810= p.D810= ENST00000414043 NM_001171167.1 810 gaC/gaT 0 +CAND1 UCSF GRCh37 12 67696174 67696174 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 103 188 0 ENST00000545606.1:c.1072G>A p.Asp358Asn p.D358N ENST00000545606 NM_018448.3 358 Gat/Aat 0 +CARD11 UCSF GRCh37 7 2977659 2977659 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 64 63 136 0 ENST00000396946.4:c.1025A>G p.Glu342Gly p.E342G ENST00000396946 NM_032415.4 342 gAg/gGg 0 +CARD14 UCSF GRCh37 17 78169384 78169384 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 16 29 0 ENST00000573882.1:c.1527C>T p.Asp509= p.D509= ENST00000573882 509 gaC/gaT 0 +CARD17 UCSF GRCh37 11 104971470 104971470 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 131 125 228 0 ENST00000375707.1:c.44G>A p.Arg15His p.R15H ENST00000375707 NM_001007232.1 15 cGt/cAt 0 +CARD9 UCSF GRCh37 9 139265296 139265296 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 21 57 0 ENST00000371732.5:c.624G>A p.Leu208= p.L208= ENST00000371732 NM_052813.4 208 ctG/ctA 0 +CASC5 UCSF GRCh37 15 40915103 40915103 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 99 194 0 ENST00000346991.5:c.2719G>A p.Glu907Lys p.E907K ENST00000346991 907 Gaa/Aaa 0 +CASKIN2 UCSF GRCh37 17 73501718 73501718 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 60 116 0 ENST00000321617.3:c.850C>T p.Leu284= p.L284= ENST00000321617 NM_020753.4 284 Ctg/Ttg 0 +CASP7 UCSF GRCh37 10 115481526 115481526 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 58 147 0 ENST00000369321.2:c.463C>T p.Leu155= p.L155= ENST00000369321 NM_033338.5 155 Ctg/Ttg 0 +CASR UCSF GRCh37 3 122003642 122003642 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 61 65 0 ENST00000498619.1:c.2871C>T p.Pro957= p.P957= ENST00000498619 NM_001178065.1 957 ccC/ccT 0 +CAST UCSF GRCh37 5 96089776 96089776 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 59 136 0 ENST00000395812.2:c.1414C>T p.Pro472Ser p.P472S ENST00000395812 NM_001042440.2 472 Cca/Tca 0 +CASZ1 UCSF GRCh37 1 10720370 10720370 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 40 55 0 ENST00000377022.3:c.729C>T p.Ile243= p.I243= ENST00000377022 NM_001079843.2 243 atC/atT 0 +CATSPER1 UCSF GRCh37 11 65793321 65793321 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 30 71 0 ENST00000312106.5:c.530G>A p.Gly177Glu p.G177E ENST00000312106 NM_053054.3 177 gGg/gAg 0 +CATSPERB UCSF GRCh37 14 92159568 92159568 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 75 196 0 ENST00000256343.3:c.733G>A p.Val245Met p.V245M ENST00000256343 NM_024764.2 245 Gtg/Atg 0 +CBLN1 UCSF GRCh37 16 49315254 49315254 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 32 57 0 ENST00000219197.6:c.123C>T p.Asn41= p.N41= ENST00000219197 NM_004352.3 41 aaC/aaT 0 +CBX6 UCSF GRCh37 22 39262814 39262814 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 34 53 0 ENST00000407418.3:c.639G>A p.Lys213= p.K213= ENST00000407418 213 aaG/aaA 0 +CBY3 UCSF GRCh37 5 179106004 179106004 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 6 10 0 ENST00000376974.4:c.309C>T p.Thr103= p.T103= ENST00000376974 NM_001164444.1 103 acC/acT 0 +CCBP2 UCSF GRCh37 3 42907103 42907103 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 60 116 0 ENST00000422265.1:c.1109C>T p.Ser370Phe p.S370F ENST00000422265 NM_001296.4 370 tCt/tTt 0 +CCDC108 UCSF GRCh37 2 219870840 219870840 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 32 63 0 ENST00000341552.5:c.4825C>T p.Pro1609Ser p.P1609S ENST00000341552 NM_194302.3 1609 Cca/Tca 0 +CCDC109B UCSF GRCh37 4 110606512 110606512 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 62 143 0 ENST00000394650.4:c.922G>A p.Asp308Asn p.D308N ENST00000394650 NM_017918.4 308 Gac/Aac 0 +CCDC120 UCSF GRCh37 X 48920079 48920079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 16 43 0 ENST00000422185.2:c.130G>A p.Glu44Lys p.E44K ENST00000422185 NM_001163322.2 44 Gag/Aag 0 +CCDC129 UCSF GRCh37 7 31692331 31692331 + intron_variant Intron SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 70 179 0 ENST00000451887.2:c.3067+34C>T *1023* ENST00000451887 NM_001257968.1 0 +CCDC151 UCSF GRCh37 19 11537720 11537720 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 35 52 0 ENST00000356392.4:c.585G>A p.Ala195= p.A195= ENST00000356392 NM_145045.4 195 gcG/gcA 0 +CCDC160 UCSF GRCh37 X 133379275 133379275 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 76 164 0 ENST00000517294.1:c.445C>T p.Leu149Phe p.L149F ENST00000517294 149 Ctt/Ttt 0 +CCDC17 UCSF GRCh37 1 46087330 46087330 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 10 31 0 ENST00000528266.1:c.1164C>T p.Gly388= p.G388= ENST00000528266 388 ggC/ggT 0 +CCDC19 UCSF GRCh37 1 159847195 159847195 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 93 189 1 ENST00000368099.4:c.1102G>A p.Glu368Lys p.E368K ENST00000368099 NM_012337.2 368 Gag/Aag 0 +CCDC38 UCSF GRCh37 12 96310966 96310966 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 61 137 0 ENST00000344280.3:c.245G>A p.Ser82Asn p.S82N ENST00000344280 NM_182496.2 82 aGt/aAt 0 +CCDC38 UCSF GRCh37 12 96263314 96263314 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 99 195 0 ENST00000344280.3:c.1522C>T p.Gln508Ter p.Q508* ENST00000344280 NM_182496.2 508 Caa/Taa 0 +CCDC40 UCSF GRCh37 17 78073441 78073441 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 49 102 0 ENST00000397545.4:c.3296G>A p.Arg1099His p.R1099H ENST00000397545 NM_017950.3 1099 cGc/cAc 0 +CCDC60 UCSF GRCh37 12 119909884 119909884 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 106 204 0 ENST00000327554.2:c.256C>T p.Leu86Phe p.L86F ENST00000327554 NM_178499.3 86 Ctt/Ttt 0 +CCDC61 UCSF GRCh37 19 46519955 46519955 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 12 32 0 ENST00000595358.1:c.1095G>A p.Gln365= p.Q365= ENST00000595358 NM_001267723.1 365 caG/caA 0 +CCDC67 UCSF GRCh37 11 93122241 93122241 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 54 108 0 ENST00000298050.3:c.991C>T p.Leu331= p.L331= ENST00000298050 NM_181645.3 331 Ctg/Ttg 0 +CCDC69 UCSF GRCh37 5 150565012 150565012 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 79 173 0 ENST00000355417.2:c.586G>A p.Asp196Asn p.D196N ENST00000355417 NM_015621.2 196 Gac/Aac 0 +CCDC7 UCSF GRCh37 10 32740580 32740580 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 112 48 108 0 ENST00000362006.5:c.10G>A p.Val4Ile p.V4I ENST00000362006 NM_145023.4 4 Gta/Ata 0 +CCDC83 UCSF GRCh37 11 85627205 85627205 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 91 208 0 ENST00000280245.4:c.1102G>A p.Glu368Lys p.E368K ENST00000280245 NM_173556.3 368 Gaa/Aaa 0 +CCDC88C UCSF GRCh37 14 91766365 91766365 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 16 29 0 ENST00000389857.6:c.3685G>A p.Val1229Ile p.V1229I ENST00000389857 NM_001080414.3 1229 Gtc/Atc 0 +CCDC96 UCSF GRCh37 4 7043007 7043007 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 58 124 0 ENST00000310085.4:c.1659C>T p.Leu553= p.L553= ENST00000310085 NM_153376.2 553 ctC/ctT 0 +CCDC97 UCSF GRCh37 19 41822402 41822402 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 33 69 0 ENST00000269967.3:c.160G>A p.Asp54Asn p.D54N ENST00000269967 NM_052848.1 54 Gac/Aac 0 +CCNB3 UCSF GRCh37 X 50052651 50052651 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 47 140 0 ENST00000376042.1:c.1482G>A p.Lys494= p.K494= ENST00000376042 494 aaG/aaA 0 +CCNG1 UCSF GRCh37 5 162866334 162866334 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 85 187 0 ENST00000340828.2:c.72G>A p.Glu24= p.E24= ENST00000340828 NM_004060.3 24 gaG/gaA 0 +CCT6B UCSF GRCh37 17 33269619 33269619 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 32 117 0 ENST00000314144.5:c.769G>A p.Glu257Lys p.E257K ENST00000314144 NM_006584.3 257 Gag/Aag 0 +CCT8 UCSF GRCh37 21 30439086 30439086 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 47 127 0 ENST00000286788.4:c.575C>T p.Pro192Leu p.P192L ENST00000286788 NM_006585.2 192 cCt/cTt 0 +CD109 UCSF GRCh37 6 74519837 74519837 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 23 56 0 ENST00000287097.5:c.3486C>T p.Ile1162= p.I1162= ENST00000287097 1162 atC/atT 0 +CD163 UCSF GRCh37 12 7635298 7635298 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 96 209 0 ENST00000359156.4:c.3188C>T p.Ala1063Val p.A1063V ENST00000359156 NM_004244.5 1063 gCc/gTc 0 +CD163L1 UCSF GRCh37 12 7531826 7531826 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 43 127 0 ENST00000313599.3:c.2119G>A p.Val707Ile p.V707I ENST00000313599 707 Gtc/Atc 0 +CD1A UCSF GRCh37 1 158226682 158226682 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 62 158 0 ENST00000289429.5:c.711G>A p.Trp237Ter p.W237* ENST00000289429 NM_001763.2 237 tgG/tgA 0 +CD300C UCSF GRCh37 17 72537841 72537841 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 60 100 0 ENST00000330793.1:c.562G>A p.Val188Ile p.V188I ENST00000330793 NM_006678.4 188 Gtc/Atc 0 +CD34 UCSF GRCh37 1 208062847 208062847 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 36 97 0 ENST00000310833.7:c.717G>A p.Arg239= p.R239= ENST00000310833 NM_001025109.1 239 agG/agA 0 +CD80 UCSF GRCh37 3 119263481 119263481 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 78 159 0 ENST00000264246.3:c.334G>A p.Gly112Ser p.G112S ENST00000264246 NM_005191.3 112 Ggc/Agc 0 +CD93 UCSF GRCh37 20 23066153 23066153 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 84 147 0 ENST00000246006.4:c.677G>A p.Gly226Glu p.G226E ENST00000246006 NM_012072.3 226 gGg/gAg 0 +CDAN1 UCSF GRCh37 15 43023884 43023884 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 37 89 0 ENST00000356231.3:c.1673C>T p.Pro558Leu p.P558L ENST00000356231 NM_138477.2 558 cCc/cTc 0 +CDC42BPA UCSF GRCh37 1 227221096 227221096 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 60 88 0 ENST00000366769.3:c.3392G>A p.Ser1131Asn p.S1131N ENST00000366769 NM_003607.3 1131 aGt/aAt 0 +CDC42BPG UCSF GRCh37 11 64602989 64602989 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 58 100 1 ENST00000342711.5:c.1863G>A p.Glu621= p.E621= ENST00000342711 NM_017525.2 621 gaG/gaA 0 +CDC42BPG UCSF GRCh37 11 64597433 64597433 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 25 44 0 ENST00000342711.5:c.3477C>T p.Ala1159= p.A1159= ENST00000342711 NM_017525.2 1159 gcC/gcT 0 +CDH12 UCSF GRCh37 5 21765100 21765100 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 92 172 0 ENST00000382254.1:c.1502C>T p.Ala501Val p.A501V ENST00000382254 NM_004061.3 501 gCc/gTc 0 +CDH13 UCSF GRCh37 16 83065776 83065776 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 48 116 0 ENST00000268613.10:c.460G>A p.Ala154Thr p.A154T ENST00000268613 154 Gca/Aca 0 +CDH15 UCSF GRCh37 16 89245890 89245890 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 39 41 80 0 ENST00000289746.2:c.109G>A p.Ala37Thr p.A37T ENST00000289746 NM_004933.2 37 Gcg/Acg 0 +CDH16 UCSF GRCh37 16 66946301 66946301 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 65 136 0 ENST00000299752.4:c.1392G>A p.Glu464= p.E464= ENST00000299752 NM_001204744.1 464 gaG/gaA 0 +CDH2 UCSF GRCh37 18 25585916 25585916 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 71 155 0 ENST00000269141.3:c.744G>A p.Glu248= p.E248= ENST00000269141 NM_001792.3 248 gaG/gaA 0 +CDH22 UCSF GRCh37 20 44828073 44828073 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 19 26 0 ENST00000372262.3:c.1412C>T p.Ala471Val p.A471V ENST00000372262 471 gCc/gTc 0 +CDH23 UCSF GRCh37 10 73501557 73501557 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 33 70 0 ENST00000224721.6:c.4739C>T p.Ala1580Val p.A1580V ENST00000224721 NM_022124.5 1580 gCc/gTc 0 +CDH23 UCSF GRCh37 10 73574733 73574733 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 16 23 0 ENST00000398788.3:c.3043G>A p.Glu1015Lys p.E1015K ENST00000398788 NM_001171933.1 1015 Gag/Aag 0 +CDH24 UCSF GRCh37 14 23523457 23523457 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 75 154 0 ENST00000397359.3:c.865G>A p.Gly289Arg p.G289R ENST00000397359 NM_022478.3 289 Ggg/Agg 0 +CDH4 UCSF GRCh37 20 59829975 59829975 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 73 117 0 ENST00000360469.5:c.151G>A p.Gly51Arg p.G51R ENST00000360469 NM_001794.3 51 Ggg/Agg 0 +CDH4 UCSF GRCh37 20 60318838 60318838 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 16 18 0 ENST00000360469.5:c.389G>A p.Gly130Glu p.G130E ENST00000360469 NM_001794.3 130 gGa/gAa 0 +CDH6 UCSF GRCh37 5 31317805 31317805 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 67 167 0 ENST00000265071.2:c.1656G>A p.Arg552= p.R552= ENST00000265071 NM_004932.3 552 cgG/cgA 0 +CDHR3 UCSF GRCh37 7 105635292 105635292 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 45 101 0 ENST00000317716.9:c.608+1G>A p.X203_splice ENST00000317716 NM_152750.4 0 +CDK14 UCSF GRCh37 7 90741873 90741873 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 117 98 194 0 ENST00000265741.3:c.1117C>T p.His373Tyr p.H373Y ENST00000265741 NM_012395.2 373 Cat/Tat 0 +CDK15 UCSF GRCh37 2 202672281 202672281 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 71 209 0 ENST00000450471.2:c.188C>T p.Ala63Val p.A63V ENST00000450471 NM_001261435.1 63 gCc/gTc 0 +CDK15 UCSF GRCh37 2 202755512 202755512 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 39 142 0 ENST00000450471.2:c.1199-14G>A *400* ENST00000450471 NM_001261435.1 0 +CDK20 UCSF GRCh37 9 90582463 90582464 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P10_Rec Untested WXS Illumina HiSeq 10 0 ENST00000325303.8:c.955dup p.His319ProfsTer4 p.H319Pfs*4 ENST00000325303 NM_001039803.2 318 -/C 0 +CDK5R2 UCSF GRCh37 2 219825281 219825281 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 58 98 0 ENST00000302625.4:c.739C>T p.Leu247= p.L247= ENST00000302625 NM_003936.4 247 Ctg/Ttg 0 +CDK5RAP2 UCSF GRCh37 9 123291061 123291061 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 32 88 0 ENST00000349780.4:c.840G>A p.Glu280= p.E280= ENST00000349780 NM_018249.5 280 gaG/gaA 0 +CDKN2A UCSF GRCh37 9 21971017 21971017 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 0 36 38 0 ENST00000304494.5:c.341C>T p.Pro114Leu p.P114L ENST00000304494 NM_000077.4 114 cCc/cTc 0 +CDKN2AIP UCSF GRCh37 4 184367664 184367664 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 84 159 0 ENST00000504169.1:c.827G>A p.Gly276Asp p.G276D ENST00000504169 NM_017632.2 276 gGc/gAc 0 +CDKN2C UCSF GRCh37 1 51436058 51436058 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 64 120 0 ENST00000262662.1:c.18G>A p.Gly6= p.G6= ENST00000262662 6 ggG/ggA 0 +CDRT4 UCSF GRCh37 17 15341337 15341337 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 84 168 0 ENST00000312177.6:c.209C>T p.Ser70Phe p.S70F ENST00000312177 NM_001204477.1 70 tCc/tTc 0 +CDS2 UCSF GRCh37 20 5169773 5169773 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 76 174 0 ENST00000460006.1:c.1042C>T p.Leu348Phe p.L348F ENST00000460006 NM_003818.3 348 Ctc/Ttc 0 +CDS2 UCSF GRCh37 20 5170793 5170793 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 50 107 0 ENST00000460006.1:c.1251G>A p.Arg417= p.R417= ENST00000460006 NM_003818.3 417 cgG/cgA 0 +CEACAM1 UCSF GRCh37 19 43031476 43031476 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 90 231 0 ENST00000161559.6:c.141G>A p.Glu47= p.E47= ENST00000161559 NM_001712.4 47 gaG/gaA 0 +CEBPG UCSF GRCh37 19 33870315 33870315 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 51 125 0 ENST00000284000.4:c.170C>T p.Pro57Leu p.P57L ENST00000284000 NM_001806.3 57 cCc/cTc 0 +CELA3B UCSF GRCh37 1 22304890 22304890 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 49 113 0 ENST00000337107.6:c.72C>T p.Arg24= p.R24= ENST00000337107 NM_007352.2 24 cgC/cgT 0 +CELF3 UCSF GRCh37 1 151679767 151679767 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 8 0 ENST00000290583.4:c.776C>T p.Thr259Ile p.T259I ENST00000290583 NM_001172648.1 259 aCc/aTc 0 +CELF6 UCSF GRCh37 15 72579614 72579614 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 60 127 0 ENST00000287202.5:c.1438C>T p.Pro480Ser p.P480S ENST00000287202 NM_052840.4 480 Cct/Tct 0 +CELSR3 UCSF GRCh37 3 48688385 48688385 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 38 62 0 ENST00000164024.4:c.6310G>A p.Gly2104Ser p.G2104S ENST00000164024 NM_001407.2 2104 Ggc/Agc 0 +CENPF UCSF GRCh37 1 214818138 214818138 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 58 140 0 ENST00000366955.3:c.5225C>T p.Ser1742Phe p.S1742F ENST00000366955 NM_016343.3 1742 tCt/tTt 0 +CENPJ UCSF GRCh37 13 25480951 25480951 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 66 159 0 ENST00000381884.4:c.1225G>A p.Asp409Asn p.D409N ENST00000381884 NM_018451.4 409 Gac/Aac 0 +CENPJ UCSF GRCh37 13 25486880 25486880 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 85 211 0 ENST00000381884.4:c.284C>T p.Thr95Ile p.T95I ENST00000381884 NM_018451.4 95 aCc/aTc 0 +CENPO UCSF GRCh37 2 25040671 25040671 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 45 106 0 ENST00000380834.2:c.899C>T p.Ser300Phe p.S300F ENST00000380834 300 tCc/tTc 0 +CEP128 UCSF GRCh37 14 81259283 81259283 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 79 77 160 0 ENST00000555265.1:c.1381T>C p.Tyr461His p.Y461H ENST00000555265 461 Tac/Cac 0 +CEP164 UCSF GRCh37 11 117232558 117232558 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 108 172 0 ENST00000278935.3:c.401G>A p.Gly134Asp p.G134D ENST00000278935 NM_014956.4 134 gGt/gAt 0 +CEP250 UCSF GRCh37 20 34086486 34086486 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 55 164 0 ENST00000397527.1:c.3718G>A p.Ala1240Thr p.A1240T ENST00000397527 NM_007186.3 1240 Gca/Aca 0 +CEP290 UCSF GRCh37 12 88508271 88508271 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 65 180 0 ENST00000552810.1:c.1978G>A p.Glu660Lys p.E660K ENST00000552810 NM_025114.3 660 Gaa/Aaa 0 +CEP72 UCSF GRCh37 5 637780 637780 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 41 99 0 ENST00000264935.5:c.1053G>A p.Leu351= p.L351= ENST00000264935 NM_018140.3 351 ttG/ttA 0 +CEP78 UCSF GRCh37 9 80879119 80879119 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 181 85 205 0 ENST00000376597.4:c.1515C>T p.Ala505= p.A505= ENST00000376597 NM_001098802.1 505 gcC/gcT 0 +CERCAM UCSF GRCh37 9 131193495 131193495 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 126 71 136 0 ENST00000372838.4:c.1116C>T p.Leu372= p.L372= ENST00000372838 NM_016174.4 372 ctC/ctT 0 +CFD UCSF GRCh37 19 861762 861762 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 11 10 0 ENST00000327726.6:c.421G>A p.Asp141Asn p.D141N ENST00000327726 NM_001928.2 141 Gac/Aac 0 +CFHR4 UCSF GRCh37 1 196871676 196871676 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 85 202 0 ENST00000367416.2:c.184C>T p.Pro62Ser p.P62S ENST00000367416 NM_001201551.1 62 Cct/Tct 0 +CFTR UCSF GRCh37 7 117120177 117120177 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 31 100 0 ENST00000003084.6:c.29G>A p.Ser10Asn p.S10N ENST00000003084 NM_000492.3 10 aGc/aAc 0 +CGN UCSF GRCh37 1 151491365 151491365 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 53 95 0 ENST00000271636.7:c.370C>T p.Pro124Ser p.P124S ENST00000271636 NM_020770.2 124 Cct/Tct 0 +CGRRF1 UCSF GRCh37 14 55004887 55004887 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 71 142 0 ENST00000216420.7:c.785G>A p.Ser262Asn p.S262N ENST00000216420 NM_006568.2 262 aGt/aAt 0 +CH25H UCSF GRCh37 10 90966981 90966981 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 24 0 ENST00000371852.2:c.69C>T p.Leu23= p.L23= ENST00000371852 NM_003956.3 23 ctC/ctT 0 +CHAF1B UCSF GRCh37 21 37763893 37763893 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 20 27 70 0 ENST00000314103.5:c.304G>A p.Glu102Lys p.E102K ENST00000314103 NM_005441.2 102 Gag/Aag 0 +CHD4 UCSF GRCh37 12 6687042 6687042 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 51 176 0 ENST00000357008.2:c.5270G>A p.Arg1757His p.R1757H ENST00000357008 NM_001273.2 1757 cGc/cAc 0 +CHD6 UCSF GRCh37 20 40112136 40112136 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 62 85 0 ENST00000373233.3:c.2281G>A p.Asp761Asn p.D761N ENST00000373233 NM_032221.4 761 Gat/Aat 0 +CHD6 UCSF GRCh37 20 40080485 40080485 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 60 124 0 ENST00000373233.3:c.3504G>A p.Gln1168= p.Q1168= ENST00000373233 NM_032221.4 1168 caG/caA 0 +CHD7 UCSF GRCh37 8 61754586 61754586 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 64 136 0 ENST00000423902.2:c.4825G>A p.Val1609Met p.V1609M ENST00000423902 NM_017780.3 1609 Gtg/Atg 0 +CHD8 UCSF GRCh37 14 21873407 21873407 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 112 197 0 ENST00000399982.2:c.3268G>A p.Glu1090Lys p.E1090K ENST00000399982 NM_001170629.1 1090 Gag/Aag 0 +CHD9 UCSF GRCh37 16 53190447 53190447 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 158 125 264 0 ENST00000566029.1:c.446C>T p.Ser149Phe p.S149F ENST00000566029 149 tCt/tTt 0 +CHEK2 UCSF GRCh37 22 29091791 29091791 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 62 154 0 ENST00000328354.6:c.1166C>T p.Thr389Ile p.T389I ENST00000328354 NM_007194.3 389 aCc/aTc 0 +CHGB UCSF GRCh37 20 5903741 5903741 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 50 128 0 ENST00000378961.4:c.951C>T p.Ser317= p.S317= ENST00000378961 NM_001819.2 317 agC/agT 0 +CHIA UCSF GRCh37 1 111861263 111861263 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 80 178 0 ENST00000369740.1:c.878C>T p.Pro293Leu p.P293L ENST00000369740 NM_001258001.1 293 cCc/cTc 0 +CHM UCSF GRCh37 X 85133991 85133991 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 23 59 0 ENST00000357749.2:c.1588C>T p.Pro530Ser p.P530S ENST00000357749 NM_000390.2 530 Cca/Tca 0 +CHMP1B UCSF GRCh37 18 11851745 11851745 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 76 140 0 ENST00000526991.2:c.235G>A p.Val79Ile p.V79I ENST00000526991 NM_020412.4 79 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89947281 89947281 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 89 193 0 ENST00000320585.6:c.234G>A p.Lys78= p.K78= ENST00000320585 NM_012124.2 78 aaG/aaA 0 +CHRDL1 UCSF GRCh37 X 109931867 109931868 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 0 ENST00000372042.1:c.943dup p.Ile315AsnfsTer12 p.I315Nfs*12 ENST00000372042 314 -/A 0 +CHRNA10 UCSF GRCh37 11 3690508 3690508 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 31 66 0 ENST00000250699.2:c.280G>A p.Asp94Asn p.D94N ENST00000250699 NM_020402.2 94 Gac/Aac 0 +CHRNA4 UCSF GRCh37 20 61981790 61981790 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 50 97 0 ENST00000370263.4:c.973G>A p.Val325Ile p.V325I ENST00000370263 NM_000744.6 325 Gtc/Atc 0 +CHST8 UCSF GRCh37 19 34263008 34263008 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 22 34 0 ENST00000262622.4:c.315G>A p.Leu105= p.L105= ENST00000262622 NM_022467.3 105 ctG/ctA 0 +CHST9 UCSF GRCh37 18 24496452 24496452 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 163 246 0 ENST00000284224.8:c.1103G>A p.Gly368Glu p.G368E ENST00000284224 NM_031422.5 368 gGg/gAg 0 +CHST9 UCSF GRCh37 18 24497034 24497034 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 120 120 227 0 ENST00000284224.8:c.521C>T p.Thr174Ile p.T174I ENST00000284224 NM_031422.5 174 aCc/aTc 0 +CHSY3 UCSF GRCh37 5 129521088 129521088 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 78 199 0 ENST00000305031.4:c.2253C>T p.Asp751= p.D751= ENST00000305031 NM_175856.4 751 gaC/gaT 0 +CHTF18 UCSF GRCh37 16 842965 842965 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 10 11 0 ENST00000262315.9:c.1573-1G>A p.X525_splice ENST00000262315 NM_022092.2 0 +CHTF18 UCSF GRCh37 16 844054 844054 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 31 55 0 ENST00000262315.9:c.1803G>A p.Arg601= p.R601= ENST00000262315 NM_022092.2 601 agG/agA 0 +CIC UCSF GRCh37 19 42790972 42790972 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 21 45 0 ENST00000575354.2:c.117C>T p.Ser39= p.S39= ENST00000575354 NM_015125.3 39 tcC/tcT 0 +CIC UCSF GRCh37 19 42791210 42791210 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 40 64 0 ENST00000575354.2:c.270G>A p.Gly90= p.G90= ENST00000575354 NM_015125.3 90 ggG/ggA 0 +CIRBP UCSF GRCh37 19 1272022 1272022 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 52 90 0 ENST00000588030.1:c.474G>A p.Gly158= p.G158= ENST00000588030 158 ggG/ggA 0 +CIZ1 UCSF GRCh37 9 130931423 130931423 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 217 76 178 0 ENST00000393608.1:c.2203G>A p.Asp735Asn p.D735N ENST00000393608 NM_012127.2 735 Gac/Aac 0 +CKAP5 UCSF GRCh37 11 46818424 46818424 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 111 175 0 ENST00000529230.1:c.1405G>A p.Val469Met p.V469M ENST00000529230 469 Gtg/Atg 0 +CLASP1 UCSF GRCh37 2 122165194 122165194 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 157 121 219 0 ENST00000263710.4:c.2522G>A p.Gly841Asp p.G841D ENST00000263710 NM_015282.2 841 gGc/gAc 0 +CLASRP UCSF GRCh37 19 45563812 45563812 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 18 57 0 ENST00000221455.3:c.790G>A p.Gly264Arg p.G264R ENST00000221455 NM_007056.2 264 Gga/Aga 0 +CLCN6 UCSF GRCh37 1 11896117 11896117 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 31 52 0 ENST00000346436.6:c.1887C>T p.Val629= p.V629= ENST00000346436 NM_001286.3 629 gtC/gtT 0 +CLCN7 UCSF GRCh37 16 1500610 1500610 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 10 17 0 ENST00000382745.4:c.1505G>A p.Cys502Tyr p.C502Y ENST00000382745 NM_001287.5 502 tGc/tAc 0 +CLDN9 UCSF GRCh37 16 3063446 3063446 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 26 56 0 ENST00000445369.2:c.83C>T p.Pro28Leu p.P28L ENST00000445369 NM_020982.3 28 cCc/cTc 0 +CLDN9 UCSF GRCh37 16 3063919 3063919 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 29 58 0 ENST00000445369.2:c.556C>T p.Pro186Ser p.P186S ENST00000445369 NM_020982.3 186 Ccc/Tcc 0 +CLEC16A UCSF GRCh37 16 11272427 11272427 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 53 88 0 ENST00000409790.1:c.3042C>T p.Asp1014= p.D1014= ENST00000409790 NM_015226.2 1014 gaC/gaT 0 +CLEC1B UCSF GRCh37 12 10147756 10147756 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 130 241 0 ENST00000298527.6:c.528G>A p.Ser176= p.S176= ENST00000298527 NM_016509.3 176 tcG/tcA 0 +CLEC4M UCSF GRCh37 19 7828322 7828322 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 87 157 0 ENST00000327325.5:c.90C>T p.Asp30= p.D30= ENST00000327325 NM_001144909.1 30 gaC/gaT 0 +CLK4 UCSF GRCh37 5 178043923 178043923 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 37 89 0 ENST00000316308.4:c.502G>A p.Gly168Arg p.G168R ENST00000316308 NM_020666.2 168 Gga/Aga 0 +CLPB UCSF GRCh37 11 72005736 72005736 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 48 100 0 ENST00000294053.3:c.1578G>A p.Gly526= p.G526= ENST00000294053 NM_001258394.1 526 ggG/ggA 0 +CLPP UCSF GRCh37 19 6364519 6364519 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 19 24 0 ENST00000245816.4:c.424C>T p.Pro142Ser p.P142S ENST00000245816 NM_006012.2 142 Ccg/Tcg 0 +CLPTM1L UCSF GRCh37 5 1344507 1344507 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 20 73 0 ENST00000320895.5:c.222C>T p.Val74= p.V74= ENST00000320895 NM_030782.3 74 gtC/gtT 0 +CLU UCSF GRCh37 8 27462723 27462723 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 41 87 0 ENST00000316403.10:c.547G>A p.Ala183Thr p.A183T ENST00000316403 183 Gcg/Acg 0 +CLVS1 UCSF GRCh37 8 62212733 62212733 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 60 128 0 ENST00000519846.1:c.347C>T p.Pro116Leu p.P116L ENST00000519846 116 cCc/cTc 0 +CLVS2 UCSF GRCh37 6 123319199 123319199 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 77 150 0 ENST00000275162.5:c.277G>A p.Asp93Asn p.D93N ENST00000275162 NM_001010852.3 93 Gac/Aac 0 +CMIP UCSF GRCh37 16 81703821 81703821 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 59 97 0 ENST00000537098.3:c.900G>A p.Gly300= p.G300= ENST00000537098 NM_198390.2 300 ggG/ggA 0 +CMYA5 UCSF GRCh37 5 79026452 79026452 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 137 147 275 0 ENST00000446378.2:c.1864G>A p.Glu622Lys p.E622K ENST00000446378 NM_153610.3 622 Gaa/Aaa 0 +CMYA5 UCSF GRCh37 5 79029525 79029525 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 125 115 192 0 ENST00000446378.2:c.4937G>A p.Gly1646Asp p.G1646D ENST00000446378 NM_153610.3 1646 gGt/gAt 0 +CMYA5 UCSF GRCh37 5 79034504 79034504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 138 132 232 0 ENST00000446378.2:c.9916G>A p.Glu3306Lys p.E3306K ENST00000446378 NM_153610.3 3306 Gaa/Aaa 0 +CNGA1 UCSF GRCh37 4 47939393 47939393 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 134 126 236 0 ENST00000402813.3:c.1325C>T p.Ser442Phe p.S442F ENST00000402813 442 tCt/tTt 0 +CNGA1 UCSF GRCh37 4 47942856 47942856 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 63 164 0 ENST00000402813.3:c.795C>T p.Tyr265= p.Y265= ENST00000402813 265 taC/taT 0 +CNGB1 UCSF GRCh37 16 57937766 57937766 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 25 63 0 ENST00000251102.8:c.2754G>A p.Lys918= p.K918= ENST00000251102 NM_001297.4 918 aaG/aaA 0 +CNKSR2 UCSF GRCh37 X 21627446 21627446 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 87 187 0 ENST00000379510.3:c.2403C>T p.Ser801= p.S801= ENST00000379510 NM_014927.3 801 tcC/tcT 0 +CNN2 UCSF GRCh37 19 1037819 1037819 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 65 127 0 ENST00000263097.4:c.850C>T p.Pro284Ser p.P284S ENST00000263097 NM_004368.2 284 Ccc/Tcc 0 +CNPY4 UCSF GRCh37 7 99717410 99717410 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 37 86 0 ENST00000262932.3:c.43G>A p.Ala15Thr p.A15T ENST00000262932 NM_152755.1 15 Gcc/Acc 0 +CNR1 UCSF GRCh37 6 88853924 88853924 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 102 154 0 ENST00000537554.1:c.1070G>A p.Gly357Asp p.G357D ENST00000537554 NM_001160258.1 357 gGc/gAc 0 +CNTFR UCSF GRCh37 9 34557523 34557523 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 33 67 0 ENST00000378980.3:c.604+1G>A p.X202_splice ENST00000378980 NM_147164.2 0 +CNTN1 UCSF GRCh37 12 41330588 41330588 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 102 182 0 ENST00000551295.2:c.991C>T p.Pro331Ser p.P331S ENST00000551295 NM_001843.3 331 Cct/Tct 0 +CNTN2 UCSF GRCh37 1 205038637 205038637 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 22 41 0 ENST00000331830.4:c.2144C>T p.Ser715Leu p.S715L ENST00000331830 NM_005076.3 715 tCa/tTa 0 +CNTN2 UCSF GRCh37 1 205039621 205039621 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 14 44 0 ENST00000331830.4:c.2499G>A p.Trp833Ter p.W833* ENST00000331830 NM_005076.3 833 tgG/tgA 0 +COBRA1 UCSF GRCh37 9 140151381 140151381 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 50 118 0 ENST00000343053.4:c.472G>A p.Gly158Arg p.G158R ENST00000343053 NM_015456.3 158 Ggg/Agg 0 +COIL UCSF GRCh37 17 55028356 55028356 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 62 113 0 ENST00000240316.4:c.247G>A p.Val83Ile p.V83I ENST00000240316 NM_004645.2 83 Gtt/Att 0 +COL12A1 UCSF GRCh37 6 75898105 75898105 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 73 183 0 ENST00000322507.8:c.970C>T p.Leu324Phe p.L324F ENST00000322507 NM_004370.5 324 Ctt/Ttt 0 +COL14A1 UCSF GRCh37 8 121215987 121215987 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 36 85 0 ENST00000297848.3:c.917C>T p.Ala306Val p.A306V ENST00000297848 NM_021110.2 306 gCc/gTc 0 +COL14A1 UCSF GRCh37 8 121313017 121313017 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 304 89 204 0 ENST00000297848.3:c.4361C>T p.Ser1454Phe p.S1454F ENST00000297848 NM_021110.2 1454 tCt/tTt 0 +COL15A1 UCSF GRCh37 9 101810250 101810250 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 37 58 0 ENST00000375001.3:c.2761G>A p.Gly921Ser p.G921S ENST00000375001 NM_001855.4 921 Ggt/Agt 0 +COL19A1 UCSF GRCh37 6 70608851 70608851 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 35 120 0 ENST00000322773.4:c.103C>T p.Pro35Ser p.P35S ENST00000322773 NM_001858.4 35 Cct/Tct 0 +COL19A1 UCSF GRCh37 6 70859755 70859755 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 100 154 1 ENST00000322773.4:c.1942C>T p.Leu648Phe p.L648F ENST00000322773 NM_001858.4 648 Ctc/Ttc 0 +COL1A1 UCSF GRCh37 17 48263779 48263779 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 91 170 0 ENST00000225964.5:c.3904C>T p.Pro1302Ser p.P1302S ENST00000225964 NM_000088.3 1302 Ccc/Tcc 0 +COL1A1 UCSF GRCh37 17 48270368 48270368 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 21 43 0 ENST00000225964.5:c.1808C>T p.Pro603Leu p.P603L ENST00000225964 NM_000088.3 603 cCc/cTc 0 +COL1A2 UCSF GRCh37 7 94052288 94052288 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 82 180 0 ENST00000297268.6:c.2423G>A p.Gly808Asp p.G808D ENST00000297268 NM_000089.3 808 gGt/gAt 0 +COL1A2 UCSF GRCh37 7 94054440 94054440 + synonymous_variant Silent SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 30 14 95 0 ENST00000297268.6:c.2685T>C p.Gly895= p.G895= ENST00000297268 NM_000089.3 895 ggT/ggC 0 +COL22A1 UCSF GRCh37 8 139838948 139838948 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 255 51 110 1 ENST00000303045.6:c.922G>A p.Glu308Lys p.E308K ENST00000303045 NM_152888.1 308 Gaa/Aaa 0 +COL22A1 UCSF GRCh37 8 139611048 139611048 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 158 37 112 0 ENST00000303045.6:c.4279C>T p.Leu1427= p.L1427= ENST00000303045 NM_152888.1 1427 Ctg/Ttg 0 +COL23A1 UCSF GRCh37 5 177669372 177669372 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 26 69 0 ENST00000390654.3:c.1464G>A p.Glu488= p.E488= ENST00000390654 NM_173465.3 488 gaG/gaA 0 +COL23A1 UCSF GRCh37 5 177690266 177690266 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 21 26 47 0 ENST00000390654.3:c.582C>T p.Ala194= p.A194= ENST00000390654 NM_173465.3 194 gcC/gcT 0 +COL24A1 UCSF GRCh37 1 86200550 86200550 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 76 174 0 ENST00000370571.2:c.4880G>A p.Arg1627Lys p.R1627K ENST00000370571 NM_152890.5 1627 aGg/aAg 0 +COL27A1 UCSF GRCh37 9 116930191 116930191 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 43 77 0 ENST00000356083.3:c.356G>A p.Ser119Asn p.S119N ENST00000356083 NM_032888.2 119 aGc/aAc 0 +COL28A1 UCSF GRCh37 7 7493129 7493129 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 61 145 0 ENST00000399429.3:c.1382G>A p.Gly461Asp p.G461D ENST00000399429 NM_001037763.2 461 gGt/gAt 0 +COL28A1 UCSF GRCh37 7 7572463 7572463 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 94 201 0 ENST00000399429.3:c.44C>T p.Ala15Val p.A15V ENST00000399429 NM_001037763.2 15 gCg/gTg 0 +COL2A1 UCSF GRCh37 12 48377895 48377895 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 7 23 0 ENST00000380518.3:c.1916G>A p.Gly639Asp p.G639D ENST00000380518 NM_033150.2 639 gGt/gAt 0 +COL3A1 UCSF GRCh37 2 189849927 189849927 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 58 154 0 ENST00000304636.3:c.287C>T p.Thr96Ile p.T96I ENST00000304636 NM_000090.3 96 aCt/aTt 0 +COL4A6 UCSF GRCh37 X 107408120 107408120 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 32 55 0 ENST00000372216.4:c.3960G>A p.Glu1320= p.E1320= ENST00000372216 NM_001847.2 1320 gaG/gaA 0 +COL6A3 UCSF GRCh37 2 238261999 238261999 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 22 65 0 ENST00000295550.4:c.6675G>A p.Gly2225= p.G2225= ENST00000295550 NM_004369.3 2225 ggG/ggA 0 +COL6A5 UCSF GRCh37 3 130159572 130159572 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 85 213 0 ENST00000265379.6:c.6390C>T p.Tyr2130= p.Y2130= ENST00000265379 NM_001278298.1 2130 taC/taT 0 +COL6A6 UCSF GRCh37 3 130293243 130293243 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 98 175 0 ENST00000358511.6:c.3421G>A p.Asp1141Asn p.D1141N ENST00000358511 NM_001102608.1 1141 Gat/Aat 0 +COL9A1 UCSF GRCh37 6 70972963 70972963 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 21 64 0 ENST00000357250.6:c.1379G>A p.Gly460Glu p.G460E ENST00000357250 NM_001851.4 460 gGa/gAa 0 +COLEC12 UCSF GRCh37 18 346738 346738 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 64 129 0 ENST00000400256.3:c.884G>A p.Gly295Asp p.G295D ENST00000400256 NM_130386.2 295 gGt/gAt 0 +COQ10B UCSF GRCh37 2 198334869 198334869 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 24 91 0 ENST00000263960.2:c.523C>T p.Pro175Ser p.P175S ENST00000263960 NM_025147.3 175 Cca/Tca 0 +COQ2 UCSF GRCh37 4 84205914 84205914 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 18 31 0 ENST00000311469.4:c.154C>T p.Leu52= p.L52= ENST00000311469 NM_015697.7 52 Ctg/Ttg 0 +CORO2A UCSF GRCh37 9 100897104 100897104 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 25 43 0 ENST00000343933.5:c.452C>T p.Ala151Val p.A151V ENST00000343933 NM_003389.3 151 gCt/gTt 0 +COX4I1 UCSF GRCh37 16 85840402 85840402 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 66 120 0 ENST00000562336.1:c.432G>A p.Arg144= p.R144= ENST00000562336 144 agG/agA 0 +CPAMD8 UCSF GRCh37 19 17014386 17014386 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0021 P10_Rec Untested WXS Illumina HiSeq 84 63 126 0 ENST00000443236.1:c.4596C>T p.Gly1532= p.G1532= ENST00000443236 NM_015692.2 1532 ggC/ggT 0 +CPNE4 UCSF GRCh37 3 131268852 131268852 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 67 141 0 ENST00000512055.1:c.1241C>T p.Ala414Val p.A414V ENST00000512055 414 gCc/gTc 0 +CPOX UCSF GRCh37 3 98311991 98311991 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 17 20 0 ENST00000264193.2:c.358G>A p.Glu120Lys p.E120K ENST00000264193 NM_000097.5 120 Gag/Aag 0 +CPPED1 UCSF GRCh37 16 12798798 12798798 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 57 103 0 ENST00000381774.4:c.398C>T p.Thr133Ile p.T133I ENST00000381774 NM_018340.2 133 aCc/aTc 0 +CPS1 UCSF GRCh37 2 211465437 211465437 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 75 191 0 ENST00000430249.2:c.1725+1G>A p.X575_splice ENST00000430249 NM_001122633.2 0 +CPSF4 UCSF GRCh37 7 99051688 99051688 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 78 139 0 ENST00000292476.5:c.670G>A p.Val224Ile p.V224I ENST00000292476 224 Gtc/Atc 0 +CRAMP1L UCSF GRCh37 16 1706298 1706298 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 18 30 0 ENST00000397412.3:c.1540C>T p.Pro514Ser p.P514S ENST00000397412 514 Ccc/Tcc 0 +CRB2 UCSF GRCh37 9 126132611 126132611 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 31 80 0 ENST00000373631.3:c.1279C>T p.Pro427Ser p.P427S ENST00000373631 NM_173689.5 427 Cca/Tca 0 +CREB3 UCSF GRCh37 9 35736396 35736396 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 95 127 0 ENST00000353704.2:c.789C>T p.Ser263= p.S263= ENST00000353704 NM_006368.4 263 tcC/tcT 0 +CREB3L4 UCSF GRCh37 1 153941022 153941022 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 58 105 0 ENST00000368607.3:c.21C>T p.Asp7= p.D7= ENST00000368607 NM_001255980.1 7 gaC/gaT 0 +CRISPLD1 UCSF GRCh37 8 75941713 75941713 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 34 119 0 ENST00000262207.4:c.1412C>T p.Thr471Ile p.T471I ENST00000262207 NM_031461.5 471 aCc/aTc 0 +CRTAM UCSF GRCh37 11 122726526 122726526 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 45 173 0 ENST00000227348.4:c.614G>A p.Gly205Glu p.G205E ENST00000227348 NM_019604.2 205 gGg/gAg 0 +CRTC2 UCSF GRCh37 1 153923901 153923901 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 19 35 0 ENST00000368633.1:c.1239C>T p.Ala413= p.A413= ENST00000368633 NM_181715.2 413 gcC/gcT 0 +CRTC3 UCSF GRCh37 15 91162994 91162994 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 37 116 0 ENST00000268184.6:c.721C>T p.Pro241Ser p.P241S ENST00000268184 241 Cct/Tct 0 +CRYM UCSF GRCh37 16 21286866 21286866 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 42 78 1 ENST00000219599.3:c.374C>T p.Ala125Val p.A125V ENST00000219599 NM_001888.3 125 gCc/gTc 0 +CRYZL1 UCSF GRCh37 21 34989027 34989027 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 64 134 0 ENST00000381554.3:c.247G>A p.Asp83Asn p.D83N ENST00000381554 NM_145858.2 83 Gat/Aat 0 +CSF1 UCSF GRCh37 1 110456983 110456983 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 40 83 0 ENST00000329608.6:c.142C>T p.Leu48= p.L48= ENST00000329608 NM_000757.5 48 Ctg/Ttg 0 +CSF3R UCSF GRCh37 1 36941258 36941258 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 25 65 0 ENST00000361632.4:c.81G>A p.Gly27= p.G27= ENST00000361632 27 ggG/ggA 0 +CSMD1 UCSF GRCh37 8 3566007 3566008 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 0 ENST00000537824.1:c.938dup p.Ala314GlyfsTer3 p.A314Gfs*3 ENST00000537824 NM_033225.5 313 aag/aAag 0 +CSMD2 UCSF GRCh37 1 34164377 34164377 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 72 129 0 ENST00000241312.4:c.3781G>A p.Asp1261Asn p.D1261N ENST00000241312 1261 Gac/Aac 0 +CSMD3 UCSF GRCh37 8 113275893 113275893 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 173 50 110 0 ENST00000297405.5:c.9837G>A p.Trp3279Ter p.W3279* ENST00000297405 NM_198123.1 3279 tgG/tgA 0 +CSNK1G1 UCSF GRCh37 15 64472608 64472608 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 51 102 0 ENST00000303052.7:c.1153G>A p.Gly385Arg p.G385R ENST00000303052 NM_022048.3 385 Gga/Aga 0 +CSPG4 UCSF GRCh37 15 75968078 75968078 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 50 81 0 ENST00000308508.5:c.6782C>T p.Thr2261Ile p.T2261I ENST00000308508 NM_001897.4 2261 aCt/aTt 0 +CST1 UCSF GRCh37 20 23731336 23731336 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 54 108 0 ENST00000304749.2:c.168C>T p.Asn56= p.N56= ENST00000304749 NM_001898.2 56 aaC/aaT 0 +CSTF3 UCSF GRCh37 11 33118465 33118465 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 58 154 0 ENST00000323959.4:c.1188G>A p.Met396Ile p.M396I ENST00000323959 NM_001326.2 396 atG/atA 0 +CTAG2 UCSF GRCh37 X 153880590 153880590 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 63 102 0 ENST00000247306.4:c.585G>A p.Gly195= p.G195= ENST00000247306 NM_020994.3 195 ggG/ggA 0 +CTAGE1 UCSF GRCh37 18 19996271 19996271 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 132 89 199 0 ENST00000391403.2:c.1504G>A p.Ala502Thr p.A502T ENST00000391403 NM_172241.2 502 Gct/Act 0 +CTAGE6P UCSF GRCh37 7 143453428 143453428 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 165 79 316 0 ENST00000470691.2:c.1324G>A p.Glu442Lys p.E442K ENST00000470691 NM_178561.4 442 Gaa/Aaa 0 +CTBP2 UCSF GRCh37 10 126716248 126716248 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 36 48 0 ENST00000309035.6:c.81G>A p.Glu27= p.E27= ENST00000309035 NM_022802.2 27 gaG/gaA 0 +CTC1 UCSF GRCh37 17 8138531 8138531 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 52 85 0 ENST00000315684.8:c.1279G>A p.Gly427Ser p.G427S ENST00000315684 NM_025099.5 427 Ggc/Agc 0 +CTNNA3 UCSF GRCh37 10 68940213 68940213 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 71 182 0 ENST00000433211.2:c.909C>T p.Arg303= p.R303= ENST00000433211 NM_013266.2 303 cgC/cgT 0 +CTPS2 UCSF GRCh37 X 16638419 16638419 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 85 203 0 ENST00000443824.1:c.1430G>A p.Arg477Lys p.R477K ENST00000443824 NM_001144002.1 477 aGa/aAa 0 +CTSC UCSF GRCh37 11 88042421 88042421 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 34 121 0 ENST00000227266.5:c.551C>T p.Ser184Phe p.S184F ENST00000227266 NM_001814.4 184 tCt/tTt 0 +CTTNBP2 UCSF GRCh37 7 117364699 117364699 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 69 74 142 0 ENST00000160373.3:c.4349G>A p.Gly1450Glu p.G1450E ENST00000160373 NM_033427.2 1450 gGa/gAa 0 +CTTNBP2NL UCSF GRCh37 1 112999829 112999829 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 90 169 0 ENST00000271277.6:c.1715C>T p.Pro572Leu p.P572L ENST00000271277 NM_018704.2 572 cCc/cTc 0 +CTU2 UCSF GRCh37 16 88780121 88780121 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 73 108 0 ENST00000453996.2:c.940G>A p.Glu314Lys p.E314K ENST00000453996 NM_001012759.1 314 Gag/Aag 0 +CUBN UCSF GRCh37 10 17032352 17032352 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 197 65 178 0 ENST00000377833.4:c.4331G>A p.Cys1444Tyr p.C1444Y ENST00000377833 NM_001081.3 1444 tGc/tAc 0 +CUL2 UCSF GRCh37 10 35299354 35299354 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 53 111 0 ENST00000537177.1:c.2180G>A p.Arg727Lys p.R727K ENST00000537177 NM_001198779.1 727 aGa/aAa 0 +CUL7 UCSF GRCh37 6 43017703 43017703 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 75 204 0 ENST00000535468.1:c.1819G>A p.Glu607Lys p.E607K ENST00000535468 NM_014780.4 607 Gag/Aag 0 +CUL7 UCSF GRCh37 6 43013324 43013324 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 46 73 0 ENST00000535468.1:c.3114+1G>A p.X1038_splice ENST00000535468 NM_014780.4 0 +CUL9 UCSF GRCh37 6 43156415 43156415 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 54 97 0 ENST00000252050.4:c.2142G>A p.Glu714= p.E714= ENST00000252050 NM_015089.2 714 gaG/gaA 0 +CUX1 UCSF GRCh37 7 101882782 101882782 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 60 144 0 ENST00000360264.3:c.3838C>T p.Pro1280Ser p.P1280S ENST00000360264 NM_001202543.1 1280 Ccg/Tcg 0 +CUX2 UCSF GRCh37 12 111760369 111760369 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 10 25 0 ENST00000261726.6:c.2911C>T p.Pro971Ser p.P971S ENST00000261726 NM_015267.3 971 Cct/Tct 0 +CXCL1 UCSF GRCh37 4 74735288 74735288 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 32 58 0 ENST00000395761.3:c.100+1G>A p.X34_splice ENST00000395761 NM_001511.3 0 +CXCR5 UCSF GRCh37 11 118764684 118764684 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 50 80 0 ENST00000292174.4:c.431C>T p.Ala144Val p.A144V ENST00000292174 NM_001716.4 144 gCc/gTc 0 +CXXC1 UCSF GRCh37 18 47812480 47812480 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 68 126 0 ENST00000412036.2:c.371C>T p.Ser124Leu p.S124L ENST00000412036 124 tCa/tTa 0 +CYB561 UCSF GRCh37 17 61511818 61511818 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 16 25 0 ENST00000392976.1:c.701C>T p.Ala234Val p.A234V ENST00000392976 NM_001017916.1 234 gCc/gTc 0 +CYB5D1 UCSF GRCh37 17 7761957 7761957 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 54 108 0 ENST00000332439.4:c.271C>T p.Leu91= p.L91= ENST00000332439 NM_144607.4 91 Ctg/Ttg 0 +CYBASC3 UCSF GRCh37 11 61121326 61121326 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 42 74 0 ENST00000426130.2:c.374G>A p.Gly125Glu p.G125E ENST00000426130 NM_001161454.1 125 gGa/gAa 0 +CYFIP1 UCSF GRCh37 15 22993045 22993045 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 18 58 0 ENST00000313077.7:c.2932C>T p.His978Tyr p.H978Y ENST00000313077 NM_014608.2 978 Cac/Tac 0 +CYHR1 UCSF GRCh37 8 145676143 145676143 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 8 16 0 ENST00000438911.2:c.708C>T p.Phe236= p.F236= ENST00000438911 NM_138496.1 236 ttC/ttT 0 +CYP1A2 UCSF GRCh37 15 75042111 75042111 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 101 205 0 ENST00000343932.4:c.32C>T p.Ala11Val p.A11V ENST00000343932 NM_000761.3 11 gCc/gTc 0 +CYP1A2 UCSF GRCh37 15 75042559 75042559 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 95 174 0 ENST00000343932.4:c.480C>T p.Tyr160= p.Y160= ENST00000343932 NM_000761.3 160 taC/taT 0 +CYP27C1 UCSF GRCh37 2 127961147 127961147 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 70 139 0 ENST00000335247.7:c.-22G>A p.X8_splice ENST00000335247 NM_001001665.3 0 +CYP2C19 UCSF GRCh37 10 96540357 96540357 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 89 229 0 ENST00000371321.3:c.583C>T p.Leu195Phe p.L195F ENST00000371321 NM_000769.1 195 Ctt/Ttt 0 +CYP2J2 UCSF GRCh37 1 60366771 60366771 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 46 127 0 ENST00000371204.3:c.1196C>T p.Thr399Ile p.T399I ENST00000371204 NM_000775.2 399 aCc/aTc 0 +CYP2S1 UCSF GRCh37 19 41703712 41703712 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 31 84 0 ENST00000310054.4:c.372G>A p.Trp124Ter p.W124* ENST00000310054 NM_030622.6 124 tgG/tgA 0 +CYP4F22 UCSF GRCh37 19 15636309 15636309 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 27 49 0 ENST00000269703.3:c.162C>T p.Arg54= p.R54= ENST00000269703 NM_173483.3 54 cgC/cgT 0 +CYTH1 UCSF GRCh37 17 76696430 76696430 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 22 51 0 ENST00000361101.4:c.533G>A p.Gly178Asp p.G178D ENST00000361101 NM_017456.2 178 gGc/gAc 0 +DAAM1 UCSF GRCh37 14 59821883 59821883 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 62 168 0 ENST00000395125.1:c.2387C>T p.Ala796Val p.A796V ENST00000395125 NM_014992.2 796 gCa/gTa 0 +DAB2 UCSF GRCh37 5 39382822 39382822 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 68 159 0 ENST00000320816.6:c.1239G>A p.Lys413= p.K413= ENST00000320816 NM_001343.3 413 aaG/aaA 0 +DACT1 UCSF GRCh37 14 59113147 59113147 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 20 29 0 ENST00000335867.4:c.1806G>A p.Arg602= p.R602= ENST00000335867 602 agG/agA 0 +DAGLA UCSF GRCh37 11 61505189 61505189 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 39 82 0 ENST00000257215.5:c.1545C>T p.Phe515= p.F515= ENST00000257215 NM_006133.2 515 ttC/ttT 0 +DAK UCSF GRCh37 11 61105600 61105600 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 42 61 0 ENST00000394900.3:c.191C>T p.Ala64Val p.A64V ENST00000394900 NM_015533.3 64 gCt/gTt 0 +DALRD3 UCSF GRCh37 3 49053920 49053920 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 1 41 86 0 ENST00000341949.4:c.1088G>A p.Gly363Asp p.G363D ENST00000341949 NM_001009996.2 363 gGt/gAt 0 +DAP3 UCSF GRCh37 1 155686916 155686916 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 87 187 1 ENST00000368336.5:c.165C>T p.Asp55= p.D55= ENST00000368336 NM_004632.3 55 gaC/gaT 0 +DAXX UCSF GRCh37 6 33289341 33289341 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 83 83 180 0 ENST00000374542.5:c.211C>T p.Leu71Phe p.L71F ENST00000374542 NM_001141970.1 71 Ctt/Ttt 0 +DBC1 UCSF GRCh37 9 122075558 122075558 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 53 119 0 ENST00000265922.3:c.76G>A p.Glu26Lys p.E26K ENST00000265922 NM_014618.2 26 Gaa/Aaa 0 +DCAF4L1 UCSF GRCh37 4 41984755 41984755 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 75 149 0 ENST00000333141.5:c.946G>A p.Ala316Thr p.A316T ENST00000333141 NM_001029955.3 316 Gcc/Acc 0 +DCBLD2 UCSF GRCh37 3 98538238 98538238 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 58 158 0 ENST00000326840.6:c.895G>A p.Glu299Lys p.E299K ENST00000326840 NM_080927.3 299 Gag/Aag 0 +DCC UCSF GRCh37 18 50985745 50985745 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 99 211 0 ENST00000442544.2:c.3536C>T p.Pro1179Leu p.P1179L ENST00000442544 NM_005215.3 1179 cCc/cTc 0 +DCHS1 UCSF GRCh37 11 6662142 6662143 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P10_Rec Untested WXS Illumina HiSeq 8 0 ENST00000299441.3:c.703dup p.Arg235ProfsTer16 p.R235Pfs*16 ENST00000299441 NM_003737.2 234 -/C 0 +DCHS2 UCSF GRCh37 4 155156320 155156320 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 69 157 0 ENST00000357232.4:c.8119C>T p.Gln2707Ter p.Q2707* ENST00000357232 NM_017639.3 2707 Caa/Taa 0 +DCN UCSF GRCh37 12 91572319 91572319 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 77 137 0 ENST00000052754.5:c.11C>T p.Thr4Ile p.T4I ENST00000052754 NM_001920.3 4 aCt/aTt 0 +DCP1B UCSF GRCh37 12 2055379 2055379 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 44 111 0 ENST00000280665.6:c.1847C>T p.Thr616Ile p.T616I ENST00000280665 NM_152640.3 616 aCt/aTt 0 +DDAH1 UCSF GRCh37 1 85816190 85816190 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 94 213 0 ENST00000284031.8:c.505G>A p.Ala169Thr p.A169T ENST00000284031 NM_012137.3 169 Gca/Aca 0 +DDB2 UCSF GRCh37 11 47256340 47256340 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 67 122 0 ENST00000256996.4:c.735G>A p.Val245= p.V245= ENST00000256996 NM_000107.2 245 gtG/gtA 0 +DDR1 UCSF GRCh37 6 30862416 30862416 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 57 141 0 ENST00000376575.3:c.1481C>T p.Pro494Leu p.P494L ENST00000376575 494 cCc/cTc 0 +DDR1 UCSF GRCh37 6 30860850 30860850 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 39 80 0 ENST00000376575.3:c.1105G>A p.Val369Met p.V369M ENST00000376575 369 Gtg/Atg 0 +DDX11 UCSF GRCh37 12 31256518 31256518 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 62 78 0 ENST00000407793.2:c.2539C>T p.His847Tyr p.H847Y ENST00000407793 NM_030653.3 847 Cat/Tat 0 +DDX11 UCSF GRCh37 12 31250914 31250914 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 18 131 0 ENST00000407793.2:c.1858G>A p.Gly620Arg p.G620R ENST00000407793 NM_030653.3 620 Ggg/Agg 0 +DDX23 UCSF GRCh37 12 49230351 49230351 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 72 118 0 ENST00000308025.3:c.1236+1G>A p.X412_splice ENST00000308025 NM_004818.2 0 +DDX27 UCSF GRCh37 20 47836064 47836064 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 27 49 0 ENST00000371764.4:c.172G>A p.Asp58Asn p.D58N ENST00000371764 NM_017895.7 58 Gac/Aac 0 +DDX4 UCSF GRCh37 5 55063757 55063757 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 57 144 0 ENST00000505374.1:c.383C>T p.Ser128Phe p.S128F ENST00000505374 NM_024415.2 128 tCc/tTc 0 +DDX53 UCSF GRCh37 X 23018198 23018198 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 18 46 0 ENST00000327968.5:c.24G>A p.Trp8Ter p.W8* ENST00000327968 NM_182699.3 8 tgG/tgA 0 +DDX59 UCSF GRCh37 1 200635267 200635267 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 92 208 0 ENST00000331314.6:c.602C>T p.Pro201Leu p.P201L ENST00000331314 NM_001031725.4 201 cCc/cTc 0 +DDX6 UCSF GRCh37 11 118656891 118656891 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 136 119 231 0 ENST00000264018.4:c.70C>T p.Pro24Ser p.P24S ENST00000264018 NM_004397.4 24 Cct/Tct 0 +DECR1 UCSF GRCh37 8 91054975 91054975 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 279 80 194 0 ENST00000220764.2:c.685G>A p.Gly229Ser p.G229S ENST00000220764 NM_001359.1 229 Ggt/Agt 0 +DEFB132 UCSF GRCh37 20 239761 239761 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 74 124 0 ENST00000382376.3:c.102C>T p.Tyr34= p.Y34= ENST00000382376 NM_207469.2 34 taC/taT 0 +DENND1B UCSF GRCh37 1 197510100 197510100 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 102 223 0 ENST00000391979.2:c.316C>T p.Leu106= p.L106= ENST00000391979 NM_001195215.1 106 Cta/Tta 0 +DENND2D UCSF GRCh37 1 111731408 111731408 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 81 128 0 ENST00000357640.4:c.1015G>A p.Val339Ile p.V339I ENST00000357640 NM_024901.4 339 Gtt/Att 0 +DEPDC5 UCSF GRCh37 22 32302255 32302255 + synonymous_variant Silent SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 3 68 96 0 ENST00000382112.3:c.4557G>A p.Arg1519= p.R1519= ENST00000382112 NM_001136029.2 1519 cgG/cgA 0 +DEPDC5 UCSF GRCh37 22 32179972 32179972 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 80 181 0 ENST00000382112.3:c.562+1G>A p.X188_splice ENST00000382112 NM_001136029.2 0 +DES UCSF GRCh37 2 220286152 220286152 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 62 108 0 ENST00000373960.3:c.1114G>A p.Glu372Lys p.E372K ENST00000373960 NM_001927.3 372 Gag/Aag 0 +DET1 UCSF GRCh37 15 89074632 89074632 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 114 194 0 ENST00000564406.1:c.338G>A p.Gly113Glu p.G113E ENST00000564406 NM_017996.3 113 gGa/gAa 0 +DFNA5 UCSF GRCh37 7 24745895 24745895 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 37 69 0 ENST00000342947.3:c.1091G>A p.Gly364Glu p.G364E ENST00000342947 NM_004403.2 364 gGg/gAg 0 +DFNA5 UCSF GRCh37 7 24738789 24738789 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 43 96 0 ENST00000342947.3:c.1347G>A p.Gln449= p.Q449= ENST00000342947 NM_004403.2 449 caG/caA 0 +DFNB31 UCSF GRCh37 9 117170265 117170265 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 12 22 0 ENST00000362057.3:c.1660G>A p.Val554Ile p.V554I ENST00000362057 NM_001173425.1 554 Gtc/Atc 0 +DGCR14 UCSF GRCh37 22 19124860 19124860 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 78 156 0 ENST00000252137.6:c.1011C>T p.Asp337= p.D337= ENST00000252137 NM_022719.2 337 gaC/gaT 0 +DGCR8 UCSF GRCh37 22 20073698 20073698 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 63 116 1 ENST00000351989.3:c.212G>A p.Gly71Glu p.G71E ENST00000351989 NM_022720.6 71 gGa/gAa 0 +DHDDS UCSF GRCh37 1 26795537 26795537 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 64 115 0 ENST00000360009.2:c.920G>A p.Arg307Gln p.R307Q ENST00000360009 NM_024887.3 307 cGg/cAg 0 +DHDH UCSF GRCh37 19 49442716 49442716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 80 182 0 ENST00000221403.2:c.377C>T p.Thr126Ile p.T126I ENST00000221403 NM_014475.3 126 aCc/aTc 0 +DHRS12 UCSF GRCh37 13 52373669 52373669 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 66 131 0 ENST00000444610.2:c.190+1G>A p.X64_splice ENST00000444610 NM_001270424.1 0 +DHX29 UCSF GRCh37 5 54579056 54579056 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 41 101 0 ENST00000251636.5:c.1940G>A p.Gly647Asp p.G647D ENST00000251636 NM_019030.2 647 gGc/gAc 0 +DIDO1 UCSF GRCh37 20 61513186 61513186 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 77 162 0 ENST00000266070.4:c.4122G>A p.Lys1374= p.K1374= ENST00000266070 NM_033081.2 1374 aaG/aaA 0 +DIO3 UCSF GRCh37 14 102028251 102028251 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 50 74 0 ENST00000510508.4:c.418G>A p.Val140Met p.V140M ENST00000510508 140 Gtg/Atg 0 +DIP2C UCSF GRCh37 10 323417 323417 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 52 114 0 ENST00000280886.6:c.4519C>T p.Leu1507= p.L1507= ENST00000280886 NM_014974.2 1507 Ctg/Ttg 0 +DLD UCSF GRCh37 7 107555952 107555952 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 55 127 0 ENST00000205402.5:c.686G>A p.Gly229Asp p.G229D ENST00000205402 NM_000108.3 229 gGt/gAt 0 +DLEC1 UCSF GRCh37 3 38126876 38126876 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 54 154 0 ENST00000308059.6:c.1373C>T p.Thr458Ile p.T458I ENST00000308059 458 aCc/aTc 0 +DLG4 UCSF GRCh37 17 7122158 7122158 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 27 92 0 ENST00000399510.2:c.11G>A p.Arg4Lys p.R4K ENST00000399510 NM_001365.3 4 aGa/aAa 0 +DLG5 UCSF GRCh37 10 79567601 79567601 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 59 112 0 ENST00000372391.2:c.4749G>A p.Glu1583= p.E1583= ENST00000372391 NM_004747.3 1583 gaG/gaA 0 +DLL3 UCSF GRCh37 19 39998575 39998575 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 38 104 0 ENST00000205143.4:c.1779C>T p.Pro593= p.P593= ENST00000205143 NM_016941.3 593 ccC/ccT 0 +DMGDH UCSF GRCh37 5 78326661 78326661 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 42 88 0 ENST00000255189.3:c.1678C>T p.Pro560Ser p.P560S ENST00000255189 NM_013391.3 560 Cca/Tca 0 +DMRTA2 UCSF GRCh37 1 50885107 50885107 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 38 57 1 ENST00000404795.3:c.859G>A p.Glu287Lys p.E287K ENST00000404795 NM_032110.2 287 Gaa/Aaa 0 +DMXL2 UCSF GRCh37 15 51772750 51772750 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 116 89 181 0 ENST00000543779.2:c.6553G>A p.Glu2185Lys p.E2185K ENST00000543779 2185 Gaa/Aaa 0 +DMXL2 UCSF GRCh37 15 51860709 51860709 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 24 62 0 ENST00000543779.2:c.260G>A p.Gly87Asp p.G87D ENST00000543779 87 gGc/gAc 0 +DNAH10 UCSF GRCh37 12 124408889 124408889 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 82 151 0 ENST00000409039.3:c.11322G>A p.Trp3774Ter p.W3774* ENST00000409039 NM_207437.3 3774 tgG/tgA 0 +DNAH17 UCSF GRCh37 17 76420176 76420176 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 48 112 0 ENST00000389840.5:c.13269C>T p.Thr4423= p.T4423= ENST00000389840 4423 acC/acT 0 +DNAH17 UCSF GRCh37 17 76488815 76488815 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 52 129 0 ENST00000389840.5:c.6399C>T p.Asn2133= p.N2133= ENST00000389840 2133 aaC/aaT 0 +DNAH2 UCSF GRCh37 17 7700504 7700504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 67 173 0 ENST00000572933.1:c.7874G>A p.Gly2625Asp p.G2625D ENST00000572933 2625 gGc/gAc 0 +DNAH5 UCSF GRCh37 5 13814842 13814842 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 59 149 0 ENST00000265104.4:c.7102C>T p.Pro2368Ser p.P2368S ENST00000265104 NM_001369.2 2368 Ccc/Tcc 0 +DNAH5 UCSF GRCh37 5 13714642 13714642 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 41 101 0 ENST00000265104.4:c.12997C>T p.Leu4333= p.L4333= ENST00000265104 NM_001369.2 4333 Ctg/Ttg 0 +DNAH7 UCSF GRCh37 2 196852860 196852860 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 55 151 0 ENST00000312428.6:c.1447G>A p.Glu483Lys p.E483K ENST00000312428 NM_018897.2 483 Gag/Aag 0 +DNAH7 UCSF GRCh37 2 196726495 196726495 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 48 139 0 ENST00000312428.6:c.7682C>T p.Thr2561Ile p.T2561I ENST00000312428 NM_018897.2 2561 aCc/aTc 0 +DNAH8 UCSF GRCh37 6 38994423 38994423 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 56 113 0 ENST00000359357.3:c.13165G>A p.Glu4389Lys p.E4389K ENST00000359357 4389 Gag/Aag 0 +DNAI1 UCSF GRCh37 9 34491538 34491538 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 51 103 0 ENST00000242317.4:c.667G>A p.Ala223Thr p.A223T ENST00000242317 NM_012144.3 223 Gcc/Acc 0 +DNAJC16 UCSF GRCh37 1 15855742 15855742 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 73 157 1 ENST00000375847.3:c.142G>A p.Ala48Thr p.A48T ENST00000375847 NM_015291.2 48 Gct/Act 0 +DNAJC17 UCSF GRCh37 15 41071767 41071767 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 44 76 0 ENST00000220496.4:c.183G>A p.Glu61= p.E61= ENST00000220496 NM_018163.2 61 gaG/gaA 0 +DNAJC19 UCSF GRCh37 3 180705975 180705975 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 66 177 1 ENST00000382564.2:c.46G>A p.Gly16Arg p.G16R ENST00000382564 NM_145261.3 16 Gga/Aga 0 +DNHD1 UCSF GRCh37 11 6524079 6524079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 74 130 0 ENST00000254579.6:c.843G>A p.Met281Ile p.M281I ENST00000254579 NM_144666.2 281 atG/atA 0 +DNMT3A UCSF GRCh37 2 25458593 25458593 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 58 63 127 0 ENST00000264709.3:c.2580G>A p.Trp860Ter p.W860* ENST00000264709 NM_175629.2 860 tgG/tgA 0 +DNMT3A UCSF GRCh37 2 25470532 25470532 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 43 43 87 0 ENST00000264709.3:c.942G>A p.Trp314Ter p.W314* ENST00000264709 NM_175629.2 314 tgG/tgA 0 +DNMT3L UCSF GRCh37 21 45668988 45668988 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 13 27 0 ENST00000270172.3:c.916C>T p.Pro306Ser p.P306S ENST00000270172 NM_013369.3 306 Cca/Tca 0 +DOC2A UCSF GRCh37 16 30017765 30017765 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 72 135 0 ENST00000350119.4:c.1026C>T p.Asp342= p.D342= ENST00000350119 NM_003586.2 342 gaC/gaT 0 +DOCK10 UCSF GRCh37 2 225781483 225781483 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 63 133 0 ENST00000258390.7:c.262G>A p.Asp88Asn p.D88N ENST00000258390 NM_014689.2 88 Gat/Aat 0 +DOCK3 UCSF GRCh37 3 51378721 51378721 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 42 77 0 ENST00000266037.9:c.3820C>T p.Pro1274Ser p.P1274S ENST00000266037 NM_004947.4 1274 Cca/Tca 0 +DOCK7 UCSF GRCh37 1 62962166 62962166 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 42 129 0 ENST00000340370.5:c.4674C>T p.Asn1558= p.N1558= ENST00000340370 NM_033407.3 1558 aaC/aaT 0 +DOK2 UCSF GRCh37 8 21771109 21771109 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 56 145 0 ENST00000276420.4:c.4G>A p.Gly2Arg p.G2R ENST00000276420 NM_003974.2 2 Gga/Aga 0 +DOK7 UCSF GRCh37 4 3494641 3494641 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 16 12 0 ENST00000340083.5:c.928G>A p.Ala310Thr p.A310T ENST00000340083 NM_173660.4 310 Gcc/Acc 0 +DOLK UCSF GRCh37 9 131708637 131708637 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 197 84 168 0 ENST00000372586.3:c.946C>T p.Leu316= p.L316= ENST00000372586 NM_014908.3 316 Ctg/Ttg 0 +DOPEY1 UCSF GRCh37 6 83848015 83848015 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0014 P10_Rec Untested WXS Illumina HiSeq 110 110 266 0 ENST00000349129.2:c.4254C>T p.Leu1418= p.L1418= ENST00000349129 NM_015018.3 1418 ctC/ctT 0 +DOPEY2 UCSF GRCh37 21 37612210 37612210 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 15 23 0 ENST00000399151.3:c.3024C>T p.Thr1008= p.T1008= ENST00000399151 NM_005128.2 1008 acC/acT 0 +DPCD UCSF GRCh37 10 103368682 103368682 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 68 160 0 ENST00000370151.4:c.495C>T p.Thr165= p.T165= ENST00000370151 NM_015448.1 165 acC/acT 0 +DPF1 UCSF GRCh37 19 38714783 38714783 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 11 8 0 ENST00000355526.4:c.81G>A p.Lys27= p.K27= ENST00000355526 NM_001135155.1 27 aaG/aaA 0 +DPF1 UCSF GRCh37 19 38713076 38713076 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 62 106 0 ENST00000355526.4:c.300C>T p.Tyr100= p.Y100= ENST00000355526 NM_001135155.1 100 taC/taT 0 +DPF2 UCSF GRCh37 11 65113205 65113205 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 62 115 0 ENST00000528416.1:c.706G>A p.Glu236Lys p.E236K ENST00000528416 NM_006268.4 236 Gag/Aag 0 +DPH2 UCSF GRCh37 1 44438150 44438150 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 53 99 0 ENST00000255108.3:c.1409C>T p.Thr470Ile p.T470I ENST00000255108 NM_001384.4 470 aCa/aTa 0 +DPH5 UCSF GRCh37 1 101479318 101479318 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 78 178 0 ENST00000370109.3:c.317G>A p.Arg106Lys p.R106K ENST00000370109 NM_001077395.1 106 aGa/aAa 0 +DPYSL2 UCSF GRCh37 8 26513222 26513222 + stop_retained_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 49 87 0 ENST00000311151.5:c.1719G>A p.Ter573= p.*573= ENST00000311151 NM_001386.5 573 taG/taA 0 +DRD1 UCSF GRCh37 5 174869048 174869048 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 83 153 0 ENST00000393752.2:c.1055C>T p.Pro352Leu p.P352L ENST00000393752 NM_000794.3 352 cCt/cTt 0 +DRD3 UCSF GRCh37 3 113847651 113847651 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 117 218 0 ENST00000383673.2:c.1115G>A p.Gly372Asp p.G372D ENST00000383673 NM_000796.3 372 gGc/gAc 0 +DSC3 UCSF GRCh37 18 28611002 28611002 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 33 116 0 ENST00000360428.4:c.291G>A p.Trp97Ter p.W97* ENST00000360428 NM_001941.3 97 tgG/tgA 0 +DSCAM UCSF GRCh37 21 41385166 41385166 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 48 88 0 ENST00000400454.1:c.5834C>T p.Pro1945Leu p.P1945L ENST00000400454 NM_001271534.1 1945 cCc/cTc 0 +DSCAM UCSF GRCh37 21 41452089 41452089 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 44 147 0 ENST00000400454.1:c.4410C>T p.Thr1470= p.T1470= ENST00000400454 NM_001271534.1 1470 acC/acT 0 +DSCAML1 UCSF GRCh37 11 117303857 117303857 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 26 49 0 ENST00000321322.6:c.5203C>T p.Leu1735= p.L1735= ENST00000321322 NM_020693.2 1735 Ctg/Ttg 0 +DSE UCSF GRCh37 6 116757597 116757597 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 92 181 0 ENST00000331677.3:c.1966C>T p.Pro656Ser p.P656S ENST00000331677 656 Ccc/Tcc 0 +DSEL UCSF GRCh37 18 65179666 65179666 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 58 145 0 ENST00000310045.7:c.2210G>A p.Arg737Lys p.R737K ENST00000310045 NM_032160.2 737 aGa/aAa 0 +DST UCSF GRCh37 6 56380398 56380398 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 92 146 0 ENST00000244364.6:c.10557G>A p.Gln3519= p.Q3519= ENST00000244364 NM_015548.4 3519 caG/caA 0 +DUOX2 UCSF GRCh37 15 45401797 45401797 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 49 145 0 ENST00000603300.1:c.1159G>A p.Val387Met p.V387M ENST00000603300 NM_014080.4 387 Gtg/Atg 0 +DUOX2 UCSF GRCh37 15 45392393 45392393 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 40 103 0 ENST00000603300.1:c.3039G>A p.Glu1013= p.E1013= ENST00000603300 NM_014080.4 1013 gaG/gaA 0 +DUPD1 UCSF GRCh37 10 76818240 76818240 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 44 104 0 ENST00000338487.5:c.33G>A p.Lys11= p.K11= ENST00000338487 NM_001003892.1 11 aaG/aaA 0 +DUSP11 UCSF GRCh37 2 74007117 74007117 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 51 86 0 ENST00000272444.3:c.126G>A p.Arg42= p.R42= ENST00000272444 NM_003584.2 42 cgG/cgA 0 +DYNC1I1 UCSF GRCh37 7 95705396 95705396 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 61 136 0 ENST00000324972.6:c.1588G>A p.Asp530Asn p.D530N ENST00000324972 NM_004411.4 530 Gac/Aac 0 +DYNC2H1 UCSF GRCh37 11 103006301 103006301 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 32 106 0 ENST00000398093.3:c.2283C>T p.Tyr761= p.Y761= ENST00000398093 761 taC/taT 0 +DYRK1A UCSF GRCh37 21 38877737 38877737 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 103 217 0 ENST00000398960.2:c.1391C>T p.Pro464Leu p.P464L ENST00000398960 NM_001396.3 464 cCc/cTc 0 +DYRK1A UCSF GRCh37 21 38884582 38884582 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 76 181 0 ENST00000398960.2:c.2040C>T p.Tyr680= p.Y680= ENST00000398960 NM_001396.3 680 taC/taT 0 +DYSF UCSF GRCh37 2 71891506 71891506 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 44 81 0 ENST00000410020.3:c.5112C>T p.Asp1704= p.D1704= ENST00000410020 NM_001130987.1 1704 gaC/gaT 0 +DYTN UCSF GRCh37 2 207557959 207557959 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 79 167 0 ENST00000452335.2:c.920G>A p.Arg307Lys p.R307K ENST00000452335 NM_001093730.1 307 aGa/aAa 0 +DZIP3 UCSF GRCh37 3 108335494 108335494 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 63 159 0 ENST00000361582.3:c.365G>A p.Gly122Asp p.G122D ENST00000361582 NM_014648.3 122 gGc/gAc 0 +E2F5 UCSF GRCh37 8 86119660 86119660 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 27 91 0 ENST00000416274.2:c.551G>A p.Gly184Asp p.G184D ENST00000416274 NM_001083588.1 184 gGt/gAt 0 +ECE1 UCSF GRCh37 1 21582624 21582624 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 34 86 0 ENST00000374893.6:c.836C>T p.Thr279Ile p.T279I ENST00000374893 NM_001397.2 279 aCc/aTc 0 +ECE1 UCSF GRCh37 1 21599352 21599352 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 49 87 0 ENST00000374893.6:c.333C>T p.Ile111= p.I111= ENST00000374893 NM_001397.2 111 atC/atT 0 +ECHDC1 UCSF GRCh37 6 127611073 127611073 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 111 237 0 ENST00000531967.1:c.865G>A p.Val289Ile p.V289I ENST00000531967 NM_001139510.1 289 Gtt/Att 0 +ECM2 UCSF GRCh37 9 95277190 95277190 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 150 60 131 0 ENST00000344604.5:c.777G>A p.Arg259= p.R259= ENST00000344604 NM_001393.3 259 agG/agA 0 +ECSCR UCSF GRCh37 5 138842242 138842242 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 8 14 0 ENST00000515823.1:c.14G>A p.Gly5Glu p.G5E ENST00000515823 NM_001077693.2 5 gGa/gAa 0 +EDF1 UCSF GRCh37 9 139760663 139760663 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 14 24 0 ENST00000224073.1:c.48C>T p.Gly16= p.G16= ENST00000224073 NM_001281298.1 16 ggC/ggT 0 +EDIL3 UCSF GRCh37 5 83356203 83356203 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 58 117 0 ENST00000296591.5:c.1053G>A p.Trp351Ter p.W351* ENST00000296591 NM_005711.4 351 tgG/tgA 0 +EDN3 UCSF GRCh37 20 57897444 57897445 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 0 ENST00000337938.2:c.565dup p.Thr189AsnfsTer10 p.T189Nfs*10 ENST00000337938 NM_207034.1 187 gaa/gaAa 0 +EEF1G UCSF GRCh37 11 62340136 62340136 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 83 181 0 ENST00000329251.4:c.91G>A p.Val31Met p.V31M ENST00000329251 NM_001404.4 31 Gtg/Atg 0 +EEPD1 UCSF GRCh37 7 36324420 36324420 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 55 98 0 ENST00000242108.4:c.1167G>A p.Gly389= p.G389= ENST00000242108 NM_030636.2 389 ggG/ggA 0 +EFHA1 UCSF GRCh37 13 22141047 22141047 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 2 37 94 0 ENST00000382374.4:c.247C>T p.Pro83Ser p.P83S ENST00000382374 NM_152726.2 83 Ccg/Tcg 0 +EFHC1 UCSF GRCh37 6 52317622 52317622 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 111 228 0 ENST00000371068.5:c.710C>T p.Thr237Ile p.T237I ENST00000371068 NM_018100.3 237 aCc/aTc 0 +EFNB3 UCSF GRCh37 17 7611322 7611322 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 53 111 0 ENST00000226091.2:c.169C>T p.Arg57Trp p.R57W ENST00000226091 NM_001406.3 57 Cgg/Tgg 0 +EFR3B UCSF GRCh37 2 25377127 25377127 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 56 108 0 ENST00000403714.3:c.2372C>T p.Thr791Ile p.T791I ENST00000403714 NM_014971.1 791 aCc/aTc 0 +EHD4 UCSF GRCh37 15 42201974 42201974 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 118 191 0 ENST00000220325.4:c.1012C>T p.Leu338= p.L338= ENST00000220325 NM_139265.3 338 Cta/Tta 0 +EHD4 UCSF GRCh37 15 42211800 42211800 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 40 66 0 ENST00000220325.4:c.532C>T p.Leu178= p.L178= ENST00000220325 NM_139265.3 178 Ctg/Ttg 0 +EID2B UCSF GRCh37 19 40023266 40023266 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 27 53 0 ENST00000326282.4:c.177G>A p.Arg59= p.R59= ENST00000326282 NM_152361.1 59 cgG/cgA 0 +EIF2B4 UCSF GRCh37 2 27591954 27591954 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 49 104 0 ENST00000451130.2:c.397G>A p.Ala133Thr p.A133T ENST00000451130 NM_172195.3 133 Gcc/Acc 0 +EIF2C2 UCSF GRCh37 8 141551327 141551327 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 18 41 0 ENST00000220592.5:c.1970C>T p.Thr657Met p.T657M ENST00000220592 NM_012154.3 657 aCg/aTg 0 +EIF2C2 UCSF GRCh37 8 141554325 141554325 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 355 89 149 0 ENST00000220592.5:c.1826C>T p.Pro609Leu p.P609L ENST00000220592 NM_012154.3 609 cCc/cTc 0 +EIF3H UCSF GRCh37 8 117671106 117671106 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 179 51 173 0 ENST00000521861.1:c.403G>A p.Asp135Asn p.D135N ENST00000521861 NM_003756.2 135 Gac/Aac 0 +EIF4G1 UCSF GRCh37 3 184039886 184039886 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 47 110 0 ENST00000424196.1:c.1535C>T p.Thr512Ile p.T512I ENST00000424196 512 aCt/aTt 0 +EIF5B UCSF GRCh37 2 99977841 99977841 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 105 198 0 ENST00000289371.6:c.477G>A p.Lys159= p.K159= ENST00000289371 NM_015904.3 159 aaG/aaA 0 +ELP3 UCSF GRCh37 8 27995380 27995380 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 97 0 ENST00000256398.8:c.1072C>T p.Pro358Ser p.P358S ENST00000256398 NM_018091.5 358 Cca/Tca 0 +EML5 UCSF GRCh37 14 89171891 89171891 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 77 140 0 ENST00000554922.1:c.1867C>T p.Leu623= p.L623= ENST00000554922 NM_183387.2 623 Ctg/Ttg 0 +ENDOV UCSF GRCh37 17 78389561 78389561 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 12 33 0 ENST00000518137.1:c.168G>A p.Val56= p.V56= ENST00000518137 NM_173627.3 56 gtG/gtA 0 +ENO1 UCSF GRCh37 1 8927255 8927255 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 67 174 0 ENST00000234590.4:c.365G>A p.Gly122Asp p.G122D ENST00000234590 NM_001428.3 122 gGt/gAt 0 +ENPEP UCSF GRCh37 4 111470765 111470765 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 81 176 0 ENST00000265162.5:c.2307G>A p.Glu769= p.E769= ENST00000265162 NM_001977.3 769 gaG/gaA 0 +EOMES UCSF GRCh37 3 27758589 27758589 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 91 192 0 ENST00000295743.4:c.2033G>A p.Gly678Glu p.G678E ENST00000295743 NM_005442.3 678 gGg/gAg 0 +EPAS1 UCSF GRCh37 2 46607851 46607851 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 57 132 0 ENST00000263734.3:c.2040G>A p.Lys680= p.K680= ENST00000263734 NM_001430.4 680 aaG/aaA 0 +EPB41L4B UCSF GRCh37 9 111965953 111965953 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 150 73 158 1 ENST00000374566.3:c.1936G>A p.Ala646Thr p.A646T ENST00000374566 NM_019114.3 646 Gct/Act 0 +EPC2 UCSF GRCh37 2 149402614 149402614 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 7 18 0 ENST00000258484.6:c.28G>A p.Ala10Thr p.A10T ENST00000258484 NM_015630.3 10 Gcg/Acg 0 +EPG5 UCSF GRCh37 18 43460146 43460146 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 47 80 0 ENST00000282041.5:c.5561C>T p.Thr1854Ile p.T1854I ENST00000282041 NM_020964.2 1854 aCt/aTt 0 +EPHA10 UCSF GRCh37 1 38184480 38184480 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 17 29 0 ENST00000373048.4:c.2765C>T p.Thr922Ile p.T922I ENST00000373048 NM_001099439.1 922 aCc/aTc 0 +EPHA10 UCSF GRCh37 1 38227159 38227159 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 7 77 0 ENST00000373048.4:c.768C>T p.Cys256= p.C256= ENST00000373048 NM_001099439.1 256 tgC/tgT 0 +EPHA4 UCSF GRCh37 2 222428779 222428779 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 85 189 0 ENST00000281821.2:c.495G>A p.Lys165= p.K165= ENST00000281821 NM_004438.3 165 aaG/aaA 0 +EPHA6 UCSF GRCh37 3 96945264 96945264 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 109 201 0 ENST00000389672.5:c.1270+1G>A p.X424_splice ENST00000389672 NM_001080448.2 0 +EPHA6 UCSF GRCh37 3 97198209 97198209 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 61 113 0 ENST00000389672.5:c.2074+1G>A p.X692_splice ENST00000389672 NM_001080448.2 0 +EPHA8 UCSF GRCh37 1 22923809 22923809 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 40 103 0 ENST00000166244.3:c.1770C>T p.Pro590= p.P590= ENST00000166244 NM_020526.3 590 ccC/ccT 0 +EPHB3 UCSF GRCh37 3 184290929 184290929 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 44 61 0 ENST00000330394.2:c.821G>A p.Gly274Asp p.G274D ENST00000330394 NM_004443.3 274 gGc/gAc 0 +EPHB4 UCSF GRCh37 7 100401105 100401105 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 12 21 0 ENST00000358173.3:c.2942G>A p.Gly981Glu p.G981E ENST00000358173 NM_004444.4 981 gGa/gAa 0 +EPN1 UCSF GRCh37 19 56204063 56204063 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 12 40 0 ENST00000411543.2:c.1336G>A p.Val446Ile p.V446I ENST00000411543 NM_001130071.1 446 Gtc/Atc 0 +EPPK1 UCSF GRCh37 8 144945735 144945735 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 19 23 0 ENST00000525985.1:c.1687C>T p.Leu563= p.L563= ENST00000525985 NM_031308.2 563 Ctg/Ttg 0 +ERAP2 UCSF GRCh37 5 96232164 96232164 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 68 145 0 ENST00000437043.3:c.1327C>T p.Pro443Ser p.P443S ENST00000437043 NM_001130140.1 443 Ccg/Tcg 0 +ERBB2IP UCSF GRCh37 5 65349627 65349627 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 47 111 0 ENST00000506030.1:c.2481G>A p.Glu827= p.E827= ENST00000506030 827 gaG/gaA 0 +ERBB3 UCSF GRCh37 12 56490602 56490602 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 77 129 0 ENST00000267101.3:c.2246G>A p.Gly749Glu p.G749E ENST00000267101 NM_001982.3 749 gGa/gAa 0 +ERBB4 UCSF GRCh37 2 212589815 212589815 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 61 137 0 ENST00000342788.4:c.727G>A p.Asp243Asn p.D243N ENST00000342788 NM_005235.2 243 Gac/Aac 0 +ERCC1 UCSF GRCh37 19 45923624 45923624 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 19 54 0 ENST00000013807.5:c.383C>T p.Pro128Leu p.P128L ENST00000013807 NM_202001.2 128 cCc/cTc 0 +ERF UCSF GRCh37 19 42754626 42754626 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 46 89 0 ENST00000222329.4:c.114G>A p.Arg38= p.R38= ENST00000222329 NM_006494.2 38 cgG/cgA 0 +ERF UCSF GRCh37 19 42753580 42753580 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 19 25 0 ENST00000222329.4:c.684C>T p.Asp228= p.D228= ENST00000222329 NM_006494.2 228 gaC/gaT 0 +ERG UCSF GRCh37 21 39763610 39763610 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 41 118 0 ENST00000288319.7:c.842C>T p.Pro281Leu p.P281L ENST00000288319 NM_182918.3 281 cCc/cTc 0 +ERICH1 UCSF GRCh37 8 623456 623456 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 97 164 0 ENST00000262109.7:c.896C>T p.Ala299Val p.A299V ENST00000262109 NM_207332.1 299 gCg/gTg 0 +ERMAP UCSF GRCh37 1 43300733 43300733 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 67 154 0 ENST00000372517.2:c.458C>T p.Pro153Leu p.P153L ENST00000372517 NM_001017922.1 153 cCc/cTc 0 +ERN2 UCSF GRCh37 16 23714018 23714018 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0022 P10_Rec Untested WXS Illumina HiSeq 69 63 125 0 ENST00000256797.4:c.1004C>T p.Thr335Met p.T335M ENST00000256797 NM_033266.3 335 aCg/aTg 0 +ESD UCSF GRCh37 13 47356811 47356811 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 74 188 0 ENST00000378720.3:c.372C>T p.Val124= p.V124= ENST00000378720 NM_001984.1 124 gtC/gtT 0 +ESPL1 UCSF GRCh37 12 53680219 53680219 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 69 184 0 ENST00000257934.4:c.3699G>A p.Glu1233= p.E1233= ENST00000257934 NM_012291.4 1233 gaG/gaA 0 +ESPN UCSF GRCh37 1 6488326 6488326 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 69 105 0 ENST00000377828.1:c.335C>T p.Ala112Val p.A112V ENST00000377828 NM_031475.2 112 gCc/gTc 0 +ESPN UCSF GRCh37 1 6512025 6512025 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 22 31 0 ENST00000377828.1:c.2194G>A p.Val732Met p.V732M ENST00000377828 NM_031475.2 732 Gtg/Atg 0 +ESR1 UCSF GRCh37 6 152265335 152265335 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 76 120 0 ENST00000206249.3:c.788G>A p.Arg263Lys p.R263K ENST00000206249 NM_000125.3 263 aGa/aAa 0 +ESR1 UCSF GRCh37 6 152265501 152265501 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 94 189 0 ENST00000206249.3:c.954C>T p.Ala318= p.A318= ENST00000206249 NM_000125.3 318 gcC/gcT 0 +ETAA1 UCSF GRCh37 2 67632437 67632437 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 46 111 0 ENST00000272342.5:c.2623C>T p.Leu875Phe p.L875F ENST00000272342 NM_019002.3 875 Ctt/Ttt 0 +ETFB UCSF GRCh37 19 51853620 51853620 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 10 45 0 ENST00000354232.4:c.674C>T p.Thr225Ile p.T225I ENST00000354232 NM_001014763.1 225 aCa/aTa 0 +ETFDH UCSF GRCh37 4 159606372 159606372 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 84 172 0 ENST00000511912.1:c.606+1G>A p.X202_splice ENST00000511912 NM_004453.2 0 +ETS1 UCSF GRCh37 11 128354799 128354799 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 79 187 0 ENST00000392668.4:c.781G>A p.Asp261Asn p.D261N ENST00000392668 NM_001143820.1 261 Gac/Aac 0 +ETS1 UCSF GRCh37 11 128350152 128350152 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 28 76 0 ENST00000392668.4:c.1057C>T p.Arg353Trp p.R353W ENST00000392668 NM_001143820.1 353 Cgg/Tgg 0 +ETV6 UCSF GRCh37 12 12022684 12022684 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 69 148 0 ENST00000396373.4:c.790C>T p.Arg264Cys p.R264C ENST00000396373 NM_001987.4 264 Cgc/Tgc 0 +EVC UCSF GRCh37 4 5785446 5785446 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 44 94 0 ENST00000382674.2:c.1731G>A p.Arg577= p.R577= ENST00000382674 577 agG/agA 0 +EVC2 UCSF GRCh37 4 5624454 5624454 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 48 90 0 ENST00000344408.5:c.2311C>T p.Leu771Phe p.L771F ENST00000344408 NM_147127.4 771 Ctc/Ttc 0 +EVI5 UCSF GRCh37 1 93167697 93167697 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 30 57 0 ENST00000370331.1:c.771+1G>A p.X257_splice ENST00000370331 NM_005665.4 0 +EVPL UCSF GRCh37 17 74019607 74019607 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 47 79 0 ENST00000301607.3:c.327C>T p.His109= p.H109= ENST00000301607 NM_001988.2 109 caC/caT 0 +EXOC4 UCSF GRCh37 7 132959927 132959927 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 55 122 0 ENST00000253861.4:c.276+1G>A p.X92_splice ENST00000253861 NM_021807.3 0 +EXOSC4 UCSF GRCh37 8 145135346 145135346 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 210 33 97 0 ENST00000316052.5:c.580G>A p.Gly194Arg p.G194R ENST00000316052 NM_019037.2 194 Gga/Aga 0 +EXT1 UCSF GRCh37 8 119122868 119122868 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 266 88 180 0 ENST00000378204.2:c.418G>A p.Gly140Ser p.G140S ENST00000378204 NM_000127.2 140 Ggc/Agc 0 +EYA2 UCSF GRCh37 20 45801378 45801378 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 63 127 0 ENST00000327619.5:c.1061G>A p.Gly354Asp p.G354D ENST00000327619 NM_005244.4 354 gGc/gAc 0 +F11 UCSF GRCh37 4 187205281 187205281 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 56 149 0 ENST00000403665.2:c.1171G>A p.Gly391Arg p.G391R ENST00000403665 NM_000128.3 391 Gga/Aga 0 +F8 UCSF GRCh37 X 154066018 154066018 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 35 80 0 ENST00000360256.4:c.6910G>A p.Gly2304Arg p.G2304R ENST00000360256 NM_000132.3 2304 Gga/Aga 0 +FADS2 UCSF GRCh37 11 61624933 61624933 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 77 97 0 ENST00000278840.4:c.813G>A p.Pro271= p.P271= ENST00000278840 NM_004265.3 271 ccG/ccA 0 +FAHD2B UCSF GRCh37 2 97750012 97750012 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 47 85 0 ENST00000414820.1:c.688C>T p.Pro230Ser p.P230S ENST00000414820 230 Cca/Tca 0 +FAM102A UCSF GRCh37 9 130716147 130716147 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 52 103 0 ENST00000373095.1:c.204G>A p.Lys68= p.K68= ENST00000373095 NM_001035254.2 68 aaG/aaA 0 +FAM110A UCSF GRCh37 20 826100 826100 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 23 34 0 ENST00000304189.2:c.653G>A p.Gly218Glu p.G218E ENST00000304189 218 gGg/gAg 0 +FAM111A UCSF GRCh37 11 58920368 58920368 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 97 195 0 ENST00000528737.1:c.1227G>A p.Arg409= p.R409= ENST00000528737 409 agG/agA 0 +FAM129B UCSF GRCh37 9 130269465 130269465 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 20 30 0 ENST00000373312.3:c.1900C>T p.Pro634Ser p.P634S ENST00000373312 NM_022833.2 634 Ccc/Tcc 0 +FAM129B UCSF GRCh37 9 130289497 130289497 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 34 55 0 ENST00000373312.3:c.291G>A p.Gly97= p.G97= ENST00000373312 NM_022833.2 97 ggG/ggA 0 +FAM135A UCSF GRCh37 6 71235693 71235693 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 55 114 0 ENST00000418814.2:c.2906C>T p.Ser969Leu p.S969L ENST00000418814 NM_001162529.1 969 tCa/tTa 0 +FAM13A UCSF GRCh37 4 89912297 89912297 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 46 91 0 ENST00000264344.5:c.432C>T p.Gly144= p.G144= ENST00000264344 NM_014883.3 144 ggC/ggT 0 +FAM149A UCSF GRCh37 4 187075793 187075793 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 40 98 0 ENST00000227065.4:c.383+1G>A p.X128_splice ENST00000227065 NM_015398.2 0 +FAM150A UCSF GRCh37 8 53451020 53451020 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 31 85 0 ENST00000358543.4:c.373C>T p.Leu125= p.L125= ENST00000358543 NM_207413.3 125 Ctg/Ttg 0 +FAM163A UCSF GRCh37 1 179783118 179783118 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 36 85 0 ENST00000341785.4:c.298C>T p.Pro100Ser p.P100S ENST00000341785 NM_173509.2 100 Cca/Tca 0 +FAM171B UCSF GRCh37 2 187626962 187626962 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 81 213 0 ENST00000304698.5:c.1893C>T p.Val631= p.V631= ENST00000304698 NM_177454.3 631 gtC/gtT 0 +FAM177A1 UCSF GRCh37 14 35515722 35515722 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 9 19 0 ENST00000280987.4:c.53C>T p.Pro18Leu p.P18L ENST00000280987 NM_173607.3 18 cCt/cTt 0 +FAM178A UCSF GRCh37 10 102672943 102672943 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 14 29 0 ENST00000370269.3:c.76C>T p.His26Tyr p.H26Y ENST00000370269 NM_001136123.1 26 Cat/Tat 0 +FAM179A UCSF GRCh37 2 29274931 29274931 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 46 125 0 ENST00000379558.4:c.3032G>A p.Gly1011Asp p.G1011D ENST00000379558 NM_199280.2 1011 gGc/gAc 0 +FAM196A UCSF GRCh37 10 128973748 128973748 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 54 88 0 ENST00000522781.1:c.912C>T p.Ala304= p.A304= ENST00000522781 NM_001039762.2 304 gcC/gcT 0 +FAM199X UCSF GRCh37 X 103432806 103432806 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 139 114 222 0 ENST00000493442.1:c.815C>T p.Thr272Ile p.T272I ENST00000493442 NM_207318.3 272 aCc/aTc 0 +FAM19A2 UCSF GRCh37 12 62148678 62148678 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0015 P10_Rec Untested WXS Illumina HiSeq 56 40 100 0 ENST00000416284.3:c.234G>A p.Thr78= p.T78= ENST00000416284 NM_178539.4 78 acG/acA 0 +FAM205A UCSF GRCh37 9 34724598 34724598 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 78 181 0 ENST00000378788.3:c.2639C>T p.Pro880Leu p.P880L ENST00000378788 NM_001141917.1 880 cCc/cTc 0 +FAM205A UCSF GRCh37 9 34726559 34726559 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 86 172 0 ENST00000378788.3:c.678G>A p.Glu226= p.E226= ENST00000378788 NM_001141917.1 226 gaG/gaA 0 +FAM208B UCSF GRCh37 10 5772512 5772512 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 143 61 151 0 ENST00000328090.5:c.550C>T p.Leu184Phe p.L184F ENST00000328090 NM_017782.4 184 Ctt/Ttt 0 +FAM208B UCSF GRCh37 10 5804588 5804588 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 170 78 182 0 ENST00000328090.5:c.7268C>T p.Ala2423Val p.A2423V ENST00000328090 NM_017782.4 2423 gCt/gTt 0 +FAM208B UCSF GRCh37 10 5790701 5790701 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 55 129 0 ENST00000328090.5:c.5317G>A p.Ala1773Thr p.A1773T ENST00000328090 NM_017782.4 1773 Gcc/Acc 0 +FAM21A UCSF GRCh37 10 51885899 51885899 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 21 140 0 ENST00000282633.5:c.2771G>A p.Gly924Asp p.G924D ENST00000282633 NM_001005751.1 924 gGt/gAt 0 +FAM22F UCSF GRCh37 9 97081362 97081362 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 71 76 0 ENST00000253262.4:c.1656C>T p.Pro552= p.P552= ENST00000253262 NM_017561.1 552 ccC/ccT 0 +FAM22G UCSF GRCh37 9 99701214 99701214 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 51 140 0 ENST00000372322.3:c.2009G>A p.Gly670Asp p.G670D ENST00000372322 NM_001170741.1 670 gGc/gAc 0 +FAM46A UCSF GRCh37 6 82459934 82459934 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 63 145 0 ENST00000320172.6:c.807G>A p.Gln269= p.Q269= ENST00000320172 NM_017633.2 269 caG/caA 0 +FAM49A UCSF GRCh37 2 16769397 16769397 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 60 127 0 ENST00000381323.3:c.-10G>A p.X4_splice ENST00000381323 NM_030797.3 0 +FAM65B UCSF GRCh37 6 24869322 24869322 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 89 156 0 ENST00000259698.4:c.414G>A p.Lys138= p.K138= ENST00000259698 NM_014722.2 138 aaG/aaA 0 +FAM70A UCSF GRCh37 X 119410813 119410813 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 88 184 0 ENST00000309720.5:c.674C>T p.Ala225Val p.A225V ENST00000309720 NM_017938.3 225 gCc/gTc 0 +FAM75C2 UCSF GRCh37 9 90746733 90746733 + non_coding_transcript_exon_variant RNA SNP C C G NOVEL P10_Rec Untested WXS Illumina HiSeq 131 259 267 1 ENST00000324915.5:n.1417G>C *473* ENST00000324915 0 +FAM84A UCSF GRCh37 2 14774305 14774305 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 24 43 0 ENST00000295092.2:c.202C>T p.Pro68Ser p.P68S ENST00000295092 NM_145175.2 68 Ccc/Tcc 0 +FANCC UCSF GRCh37 9 97869483 97869483 + synonymous_variant Silent SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 59 22 49 0 ENST00000289081.3:c.1398C>T p.Asp466= p.D466= ENST00000289081 NM_000136.2 466 gaC/gaT 0 +FANCG UCSF GRCh37 9 35079448 35079448 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 43 67 0 ENST00000378643.3:c.74G>A p.Arg25Gln p.R25Q ENST00000378643 NM_004629.1 25 cGa/cAa 0 +FANCI UCSF GRCh37 15 89843080 89843080 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 74 156 0 ENST00000310775.7:c.2686G>A p.Gly896Arg p.G896R ENST00000310775 NM_001113378.1 896 Gga/Aga 0 +FASN UCSF GRCh37 17 80045069 80045069 + missense_variant Missense_Mutation SNP G G A snp132_rs4363911 P10_Rec somatic WXS Sanger Illumina HiSeq 16 11 12 0 ENST00000306749.2:c.3284C>T p.Ser1095Phe p.S1095F ENST00000306749 NM_004104.4 1095 tCc/tTc 0 +FBN2 UCSF GRCh37 5 127653923 127653923 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 94 202 0 ENST00000508053.1:c.4635C>T p.Gly1545= p.G1545= ENST00000508053 1545 ggC/ggT 0 +FBN3 UCSF GRCh37 19 8150343 8150343 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 7 15 0 ENST00000600128.1:c.6991G>A p.Gly2331Ser p.G2331S ENST00000600128 2331 Ggc/Agc 0 +FBN3 UCSF GRCh37 19 8159401 8159401 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 24 49 0 ENST00000600128.1:c.5834G>A p.Cys1945Tyr p.C1945Y ENST00000600128 1945 tGc/tAc 0 +FBN3 UCSF GRCh37 19 8160940 8160940 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 45 101 0 ENST00000600128.1:c.5564C>T p.Pro1855Leu p.P1855L ENST00000600128 1855 cCt/cTt 0 +FBN3 UCSF GRCh37 19 8130812 8130812 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 29 79 0 ENST00000600128.1:c.8421G>A p.Gln2807= p.Q2807= ENST00000600128 2807 caG/caA 0 +FBXL19 UCSF GRCh37 16 30958069 30958069 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 17 39 0 ENST00000380310.2:c.1706G>A p.Gly569Asp p.G569D ENST00000380310 NM_001099784.2 569 gGt/gAt 0 +FBXL22 UCSF GRCh37 15 63889795 63889795 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 39 89 0 ENST00000360587.2:c.204C>T p.Gly68= p.G68= ENST00000360587 NM_203373.2 68 ggC/ggT 0 +FBXL5 UCSF GRCh37 4 15640227 15640227 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 50 128 0 ENST00000341285.3:c.487G>A p.Asp163Asn p.D163N ENST00000341285 NM_001193534.1 163 Gat/Aat 0 +FBXL6 UCSF GRCh37 8 145581850 145581850 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 4 12 0 ENST00000331890.5:c.258G>A p.Arg86= p.R86= ENST00000331890 NM_012162.3 86 agG/agA 0 +FBXO18 UCSF GRCh37 10 5957475 5957475 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 116 48 90 0 ENST00000379999.5:c.1659C>T p.Phe553= p.F553= ENST00000379999 NM_032807.4 553 ttC/ttT 0 +FBXO24 UCSF GRCh37 7 100193252 100193252 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 70 120 0 ENST00000427939.2:c.1243C>T p.Arg415Ter p.R415* ENST00000427939 NM_012172.4 415 Cga/Tga 0 +FBXO34 UCSF GRCh37 14 55817500 55817500 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 54 143 0 ENST00000313833.4:c.392G>A p.Arg131Lys p.R131K ENST00000313833 NM_017943.3 131 aGg/aAg 0 +FBXO38 UCSF GRCh37 5 147774451 147774451 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 117 84 220 0 ENST00000394370.3:c.112C>T p.Leu38Phe p.L38F ENST00000394370 38 Ctt/Ttt 0 +FBXO39 UCSF GRCh37 17 6690267 6690267 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 69 153 0 ENST00000321535.4:c.1192G>A p.Val398Ile p.V398I ENST00000321535 NM_153230.2 398 Gta/Ata 0 +FBXO40 UCSF GRCh37 3 121341947 121341947 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 70 188 0 ENST00000338040.4:c.1671G>A p.Arg557= p.R557= ENST00000338040 NM_016298.3 557 agG/agA 0 +FCGR1A UCSF GRCh37 1 149755806 149755806 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 74 206 0 ENST00000369168.4:c.300C>T p.Ile100= p.I100= ENST00000369168 NM_000566.3 100 atC/atT 0 +FCHSD1 UCSF GRCh37 5 141026182 141026182 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 30 71 0 ENST00000435817.2:c.1032C>T p.Asn344= p.N344= ENST00000435817 NM_033449.2 344 aaC/aaT 0 +FCN1 UCSF GRCh37 9 137809617 137809617 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 43 80 0 ENST00000371806.3:c.101C>T p.Pro34Leu p.P34L ENST00000371806 NM_002003.3 34 cCa/cTa 0 +FDPS UCSF GRCh37 1 155289672 155289672 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 77 139 0 ENST00000356657.6:c.1012G>A p.Val338Ile p.V338I ENST00000356657 NM_001135821.1 338 Gtt/Att 0 +FECH UCSF GRCh37 18 55218022 55218022 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 43 100 0 ENST00000382873.3:c.1212G>A p.Gln404= p.Q404= ENST00000382873 404 caG/caA 0 +FER1L5 UCSF GRCh37 2 97370003 97370003 + downstream_gene_variant 3'Flank SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 97 223 0 ENST00000377079 NM_001142292.1 0 +FER1L6 UCSF GRCh37 8 124978277 124978277 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 98 34 84 0 ENST00000522917.1:c.228G>A p.Gly76= p.G76= ENST00000522917 NM_001039112.2 76 ggG/ggA 0 +FERMT1 UCSF GRCh37 20 6060213 6060213 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 53 139 0 ENST00000217289.4:c.1730G>A p.Ser577Asn p.S577N ENST00000217289 NM_017671.4 577 aGc/aAc 0 +FERMT3 UCSF GRCh37 11 63978260 63978260 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 74 100 0 ENST00000279227.5:c.338G>A p.Arg113His p.R113H ENST00000279227 NM_178443.2 113 cGt/cAt 0 +FERMT3 UCSF GRCh37 11 63988578 63988578 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 34 81 0 ENST00000279227.5:c.1648C>T p.Leu550= p.L550= ENST00000279227 NM_178443.2 550 Ctg/Ttg 0 +FFAR3 UCSF GRCh37 19 35849937 35849937 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 216 68 308 0 ENST00000327809.4:c.145G>A p.Ala49Thr p.A49T ENST00000327809 NM_005304.3 49 Gcc/Acc 0 +FGD2 UCSF GRCh37 6 36995292 36995292 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 78 101 0 ENST00000274963.8:c.1693G>A p.Gly565Ser p.G565S ENST00000274963 NM_173558.3 565 Ggc/Agc 0 +FGF12 UCSF GRCh37 3 192125961 192125961 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 24 56 0 ENST00000454309.2:c.52G>A p.Glu18Lys p.E18K ENST00000454309 NM_021032.4 18 Gag/Aag 0 +FGF3 UCSF GRCh37 11 69631120 69631120 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 50 98 0 ENST00000334134.2:c.292G>A p.Ala98Thr p.A98T ENST00000334134 NM_005247.2 98 Gcc/Acc 0 +FGF5 UCSF GRCh37 4 81188231 81188231 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 36 104 0 ENST00000312465.7:c.253G>A p.Gly85Arg p.G85R ENST00000312465 NM_004464.3 85 Ggg/Agg 0 +FGFR1 UCSF GRCh37 8 38271242 38271242 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 14 28 0 ENST00000425967.3:c.2466G>A p.Gly822= p.G822= ENST00000425967 NM_001174067.1 822 ggG/ggA 0 +FGFR3 UCSF GRCh37 4 1807330 1807330 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 44 104 0 ENST00000260795.2:c.1579G>A p.Glu527Lys p.E527K ENST00000260795 527 Gag/Aag 0 +FHL1 UCSF GRCh37 X 135290032 135290032 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 65 130 0 ENST00000394155.2:c.413C>T p.Thr138Ile p.T138I ENST00000394155 NM_001159702.2 138 aCt/aTt 0 +FLG UCSF GRCh37 1 152285468 152285468 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 157 133 267 0 ENST00000368799.1:c.1894G>A p.Glu632Lys p.E632K ENST00000368799 NM_002016.1 632 Gaa/Aaa 0 +FLG UCSF GRCh37 1 152280068 152280068 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 115 214 0 ENST00000368799.1:c.7294G>A p.Gly2432Arg p.G2432R ENST00000368799 NM_002016.1 2432 Ggg/Agg 0 +FLG2 UCSF GRCh37 1 152323669 152323669 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 155 143 235 0 ENST00000388718.5:c.6593G>A p.Gly2198Glu p.G2198E ENST00000388718 NM_001014342.2 2198 gGa/gAa 0 +FLJ43860 UCSF GRCh37 8 142446962 142446962 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 9 19 0 ENST00000606664.1:n.2318C>T *773* ENST00000606664 0 +FLNA UCSF GRCh37 X 153592985 153592985 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 46 84 0 ENST00000369850.3:c.1931C>T p.Ala644Val p.A644V ENST00000369850 NM_001110556.1 644 gCc/gTc 0 +FLNB UCSF GRCh37 3 58149045 58149045 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 5 35 80 0 ENST00000490882.1:c.7279G>A p.Gly2427Arg p.G2427R ENST00000490882 NM_001164317.1 2427 Ggg/Agg 0 +FLNC UCSF GRCh37 7 128482991 128482991 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 21 60 0 ENST00000325888.8:c.2533G>A p.Val845Met p.V845M ENST00000325888 NM_001458.4 845 Gtg/Atg 0 +FLRT2 UCSF GRCh37 14 86088382 86088382 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 70 124 0 ENST00000330753.4:c.524C>T p.Pro175Leu p.P175L ENST00000330753 NM_013231.4 175 cCt/cTt 0 +FLT1 UCSF GRCh37 13 28880854 28880854 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 33 93 0 ENST00000282397.4:c.3776C>T p.Thr1259Ile p.T1259I ENST00000282397 NM_002019.4 1259 aCc/aTc 0 +FLT4 UCSF GRCh37 5 180053249 180053249 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 39 90 0 ENST00000261937.6:c.1120G>A p.Ala374Thr p.A374T ENST00000261937 NM_182925.4 374 Gca/Aca 0 +FLVCR1 UCSF GRCh37 1 213061276 213061276 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 41 100 0 ENST00000366971.4:c.1240G>A p.Val414Ile p.V414I ENST00000366971 NM_014053.3 414 Gtt/Att 0 +FLVCR2 UCSF GRCh37 14 76101342 76101342 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 29 80 0 ENST00000238667.4:c.1110G>A p.Arg370= p.R370= ENST00000238667 NM_017791.2 370 agG/agA 0 +FMOD UCSF GRCh37 1 203316597 203316597 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 88 173 0 ENST00000354955.4:c.802C>T p.Pro268Ser p.P268S ENST00000354955 NM_002023.4 268 Ccc/Tcc 0 +FN3K UCSF GRCh37 17 80698656 80698656 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 25 76 0 ENST00000300784.7:c.311G>A p.Gly104Glu p.G104E ENST00000300784 NM_022158.3 104 gGa/gAa 0 +FNDC3B UCSF GRCh37 3 172098803 172098803 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 72 195 0 ENST00000336824.4:c.3223G>A p.Glu1075Lys p.E1075K ENST00000336824 NM_001135095.1 1075 Gag/Aag 0 +FNIP2 UCSF GRCh37 4 159790480 159790480 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 58 89 1 ENST00000264433.6:c.2692G>A p.Gly898Arg p.G898R ENST00000264433 NM_020840.1 898 Gga/Aga 0 +FOXA1 UCSF GRCh37 14 38060636 38060636 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 44 116 0 ENST00000250448.2:c.1353G>A p.Glu451= p.E451= ENST00000250448 NM_004496.3 451 gaG/gaA 0 +FOXD4 UCSF GRCh37 9 116953 116953 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 31 93 0 ENST00000382500.2:c.1167G>A p.Leu389= p.L389= ENST00000382500 NM_207305.4 389 ctG/ctA 0 +FOXM1 UCSF GRCh37 12 2968772 2968772 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 30 76 0 ENST00000342628.2:c.1438G>A p.Glu480Lys p.E480K ENST00000342628 NM_202002.2 480 Gag/Aag 0 +FOXN2 UCSF GRCh37 2 48602534 48602534 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 50 89 0 ENST00000340553.3:c.1248C>T p.Ser416= p.S416= ENST00000340553 NM_002158.3 416 tcC/tcT 0 +FOXO3 UCSF GRCh37 6 108984734 108984734 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 51 97 0 ENST00000406360.1:c.698G>A p.Trp233Ter p.W233* ENST00000406360 NM_001455.3 233 tGg/tAg 0 +FOXRED2 UCSF GRCh37 22 36900392 36900392 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 56 92 0 ENST00000397224.4:c.802G>A p.Asp268Asn p.D268N ENST00000397224 NM_001102371.1 268 Gat/Aat 0 +FPGT-TNNI3K UCSF GRCh37 1 74905277 74905277 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 68 142 0 ENST00000370891.2:c.2285G>A p.Gly762Asp p.G762D ENST00000370891 NM_001112808.2 762 gGc/gAc 0 +FPGT UCSF GRCh37 1 74667011 74667011 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 39 112 0 ENST00000370891.2:c.260G>A p.Gly87Glu p.G87E ENST00000370891 NM_001112808.2 87 gGa/gAa 0 +FPR2 UCSF GRCh37 19 52272376 52272376 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 94 191 0 ENST00000598776.1:c.465C>T p.Val155= p.V155= ENST00000598776 NM_001462.3 155 gtC/gtT 0 +FRAS1 UCSF GRCh37 4 79239994 79239994 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 87 162 0 ENST00000264895.6:c.1991G>A p.Gly664Asp p.G664D ENST00000264895 NM_025074.6 664 gGt/gAt 0 +FRAS1 UCSF GRCh37 4 79293994 79293994 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 100 77 186 0 ENST00000264895.6:c.2992G>A p.Asp998Asn p.D998N ENST00000264895 NM_025074.6 998 Gac/Aac 0 +FRMD4A UCSF GRCh37 10 13702466 13702466 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 134 58 107 0 ENST00000357447.2:c.1748C>T p.Pro583Leu p.P583L ENST00000357447 NM_018027.3 583 cCt/cTt 0 +FRMPD2 UCSF GRCh37 10 49395323 49395323 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 22 50 0 ENST00000374201.3:c.2178C>T p.Gly726= p.G726= ENST00000374201 NM_001018071.3 726 ggC/ggT 0 +FRMPD4 UCSF GRCh37 X 12734380 12734380 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 129 102 188 1 ENST00000380682.1:c.1802A>G p.Tyr601Cys p.Y601C ENST00000380682 NM_014728.3 601 tAt/tGt 0 +FRY UCSF GRCh37 13 32735339 32735339 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 72 157 0 ENST00000380250.3:c.1843C>T p.Leu615= p.L615= ENST00000380250 NM_023037.2 615 Ctg/Ttg 0 +FSD2 UCSF GRCh37 15 83437731 83437731 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 71 155 0 ENST00000334574.8:c.1454C>T p.Ala485Val p.A485V ENST00000334574 485 gCt/gTt 0 +FSHR UCSF GRCh37 2 49191001 49191001 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 83 210 0 ENST00000406846.2:c.959C>T p.Ser320Phe p.S320F ENST00000406846 NM_000145.3 320 tCc/tTc 0 +FSTL1 UCSF GRCh37 3 120129807 120129807 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 61 145 0 ENST00000295633.3:c.323C>T p.Ala108Val p.A108V ENST00000295633 NM_007085.4 108 gCc/gTc 0 +FUK UCSF GRCh37 16 70503125 70503125 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 67 121 0 ENST00000288078.6:c.854G>A p.Arg285Lys p.R285K ENST00000288078 NM_145059.2 285 aGg/aAg 0 +FUT4 UCSF GRCh37 11 94278693 94278693 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 40 105 0 ENST00000358752.2:c.1394C>T p.Ala465Val p.A465V ENST00000358752 NM_002033.3 465 gCc/gTc 0 +FZD6 UCSF GRCh37 8 104343670 104343670 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 191 56 120 0 ENST00000358755.4:c.2054C>T p.Ser685Phe p.S685F ENST00000358755 NM_001164616.1 685 tCt/tTt 0 +G6PC3 UCSF GRCh37 17 42153172 42153172 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 83 138 0 ENST00000269097.4:c.802C>T p.Pro268Ser p.P268S ENST00000269097 NM_138387.3 268 Ccc/Tcc 0 +GABPB2 UCSF GRCh37 1 151076124 151076124 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 34 116 0 ENST00000368918.3:c.709C>T p.Pro237Ser p.P237S ENST00000368918 NM_144618.2 237 Ccc/Tcc 0 +GABRA2 UCSF GRCh37 4 46390656 46390656 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 86 209 1 ENST00000510861.1:c.68C>T p.Ala23Val p.A23V ENST00000510861 23 gCc/gTc 0 +GABRE UCSF GRCh37 X 151123325 151123325 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 36 43 57 0 ENST00000370328.3:c.1369T>C p.Phe457Leu p.F457L ENST00000370328 NM_004961.3 457 Ttc/Ctc 0 +GABRR1 UCSF GRCh37 6 89913153 89913153 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 39 138 0 ENST00000454853.2:c.173+1G>A p.X58_splice ENST00000454853 NM_001256704.1 0 +GADD45B UCSF GRCh37 19 2477570 2477570 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 14 31 0 ENST00000215631.4:c.454G>A p.Val152Ile p.V152I ENST00000215631 NM_015675.3 152 Gtc/Atc 0 +GAK UCSF GRCh37 4 860250 860250 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 13 42 0 ENST00000314167.4:c.2945G>A p.Gly982Asp p.G982D ENST00000314167 NM_005255.2 982 gGc/gAc 0 +GAL3ST4 UCSF GRCh37 7 99764134 99764134 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 60 139 0 ENST00000360039.4:c.420C>T p.Asn140= p.N140= ENST00000360039 NM_024637.4 140 aaC/aaT 0 +GALK1 UCSF GRCh37 17 73754159 73754159 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 22 30 0 ENST00000588479.1:c.1157G>A p.Gly386Glu p.G386E ENST00000588479 386 gGa/gAa 0 +GALNT1 UCSF GRCh37 18 33283592 33283592 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 51 149 0 ENST00000269195.5:c.1518G>A p.Trp506Ter p.W506* ENST00000269195 NM_020474.3 506 tgG/tgA 0 +GALNT2 UCSF GRCh37 1 230381809 230381809 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 56 119 0 ENST00000366672.4:c.730G>A p.Asp244Asn p.D244N ENST00000366672 NM_004481.3 244 Gac/Aac 0 +GALNT5 UCSF GRCh37 2 158115100 158115100 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 58 144 0 ENST00000259056.4:c.506C>T p.Pro169Leu p.P169L ENST00000259056 NM_014568.1 169 cCa/cTa 0 +GALNT5 UCSF GRCh37 2 158115564 158115564 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 88 100 165 0 ENST00000259056.4:c.970A>G p.Ile324Val p.I324V ENST00000259056 NM_014568.1 324 Att/Gtt 0 +GALNT6 UCSF GRCh37 12 51752915 51752915 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 137 136 256 0 ENST00000543196.2:c.1368+1G>A p.X456_splice ENST00000543196 0 +GALNTL1 UCSF GRCh37 14 69814702 69814702 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 38 113 0 ENST00000337827.4:c.1522C>T p.Pro508Ser p.P508S ENST00000337827 NM_020692.2 508 Cct/Tct 0 +GALR2 UCSF GRCh37 17 74071015 74071015 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 17 20 0 ENST00000329003.3:c.51C>T p.Gly17= p.G17= ENST00000329003 NM_003857.2 17 ggC/ggT 0 +GAPT UCSF GRCh37 5 57790774 57790774 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 66 154 0 ENST00000396776.2:c.411G>A p.Gln137= p.Q137= ENST00000396776 NM_152687.2 137 caG/caA 0 +GARS UCSF GRCh37 7 30672015 30672015 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 78 189 0 ENST00000389266.3:c.2056C>T p.Leu686= p.L686= ENST00000389266 NM_002047.2 686 Ctg/Ttg 0 +GAS1 UCSF GRCh37 9 89561092 89561092 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 13 31 0 ENST00000298743.7:c.603C>T p.Asp201= p.D201= ENST00000298743 NM_002048.2 201 gaC/gaT 0 +GAS7 UCSF GRCh37 17 9885131 9885131 + synonymous_variant Silent SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 48 50 117 0 ENST00000432992.2:c.375G>A p.Leu125= p.L125= ENST00000432992 NM_201433.1 125 ctG/ctA 0 +GBF1 UCSF GRCh37 10 104128582 104128582 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 64 122 0 ENST00000369983.3:c.2963G>A p.Ser988Asn p.S988N ENST00000369983 NM_004193.2 988 aGc/aAc 0 +GBGT1 UCSF GRCh37 9 136030567 136030567 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 30 89 0 ENST00000372040.3:c.357G>A p.Gly119= p.G119= ENST00000372040 119 ggG/ggA 0 +GCDH UCSF GRCh37 19 13010315 13010315 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 56 35 92 0 ENST00000222214.5:c.1277G>A p.Arg426Lys p.R426K ENST00000222214 NM_000159.3 426 aGa/aAa 0 +GCNT2 UCSF GRCh37 6 10586567 10586567 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 99 192 0 ENST00000379597.3:c.926-35017G>A *309* ENST00000379597 0 +GDF6 UCSF GRCh37 8 97157609 97157609 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 6 30 0 ENST00000287020.5:c.550C>T p.Leu184Phe p.L184F ENST00000287020 NM_001001557.2 184 Ctc/Ttc 0 +GDI2 UCSF GRCh37 10 5815904 5815904 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 137 51 129 0 ENST00000380191.4:c.720G>A p.Arg240= p.R240= ENST00000380191 NM_001494.3 240 agG/agA 0 +GDPD2 UCSF GRCh37 X 69647004 69647004 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 57 119 0 ENST00000453994.2:c.720C>T p.Thr240= p.T240= ENST00000453994 NM_001171192.1 240 acC/acT 0 +GDPD3 UCSF GRCh37 16 30123744 30123744 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 49 122 0 ENST00000406256.3:c.366C>T p.Gly122= p.G122= ENST00000406256 NM_024307.2 122 ggC/ggT 0 +GEM UCSF GRCh37 8 95264291 95264291 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 216 62 160 0 ENST00000297596.2:c.569G>A p.Gly190Asp p.G190D ENST00000297596 NM_005261.3 190 gGc/gAc 0 +GEM UCSF GRCh37 8 95262628 95262628 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 209 59 133 0 ENST00000297596.2:c.801G>A p.Arg267= p.R267= ENST00000297596 NM_005261.3 267 agG/agA 0 +GEMIN4 UCSF GRCh37 17 650358 650358 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 105 181 0 ENST00000319004.5:c.925C>T p.Pro309Ser p.P309S ENST00000319004 NM_015721.2 309 Ccc/Tcc 0 +GGCX UCSF GRCh37 2 85785661 85785661 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 78 130 0 ENST00000233838.4:c.441G>A p.Trp147Ter p.W147* ENST00000233838 NM_000821.5 147 tgG/tgA 0 +GGT7 UCSF GRCh37 20 33450626 33450626 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 32 83 0 ENST00000336431.5:c.548G>A p.Gly183Asp p.G183D ENST00000336431 NM_178026.2 183 gGc/gAc 0 +GGT7 UCSF GRCh37 20 33449338 33449338 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 46 127 0 ENST00000336431.5:c.585C>T p.Ile195= p.I195= ENST00000336431 NM_178026.2 195 atC/atT 0 +GIP UCSF GRCh37 17 47039108 47039108 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 16 41 0 ENST00000357424.2:c.331G>A p.Glu111Lys p.E111K ENST00000357424 NM_004123.2 111 Gag/Aag 0 +GJA9 UCSF GRCh37 1 39340782 39340782 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 116 96 171 0 ENST00000357771.3:c.989C>T p.Ser330Phe p.S330F ENST00000357771 NM_030772.4 330 tCt/tTt 0 +GK2 UCSF GRCh37 4 80329033 80329033 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 145 110 223 0 ENST00000358842.3:c.322C>T p.Leu108Phe p.L108F ENST00000358842 NM_033214.2 108 Ctc/Ttc 0 +GLI4 UCSF GRCh37 8 144358409 144358409 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 16 27 0 ENST00000340042.1:c.566G>A p.Gly189Asp p.G189D ENST00000340042 NM_138465.3 189 gGc/gAc 0 +GLIPR1 UCSF GRCh37 12 75892611 75892611 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 101 187 0 ENST00000266659.3:c.654C>T p.Tyr218= p.Y218= ENST00000266659 NM_006851.2 218 taC/taT 0 +GLIS2 UCSF GRCh37 16 4384834 4384834 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 47 84 0 ENST00000262366.3:c.378C>T p.Val126= p.V126= ENST00000262366 126 gtC/gtT 0 +GLIS2 UCSF GRCh37 16 4384886 4384886 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 43 69 0 ENST00000262366.3:c.430C>T p.Leu144= p.L144= ENST00000262366 144 Ctg/Ttg 0 +GLRA4 UCSF GRCh37 X 102968460 102968460 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 53 131 0 ENST00000372617.4:c.1071G>A p.Arg357= p.R357= ENST00000372617 NM_001024452.2 357 agG/agA 0 +GLTPD1 UCSF GRCh37 1 1262672 1262672 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 41 60 0 ENST00000343938.4:c.174C>T p.Val58= p.V58= ENST00000343938 NM_001029885.1 58 gtC/gtT 0 +GLYAT UCSF GRCh37 11 58478192 58478192 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 79 139 0 ENST00000344743.3:c.359C>T p.Ala120Val p.A120V ENST00000344743 NM_201648.2 120 gCc/gTc 0 +GMEB1 UCSF GRCh37 1 29030728 29030728 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 62 192 0 ENST00000294409.2:c.785G>A p.Gly262Glu p.G262E ENST00000294409 NM_006582.3 262 gGa/gAa 0 +GMEB2 UCSF GRCh37 20 62227072 62227072 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 34 70 0 ENST00000266068.1:c.510C>T p.Val170= p.V170= ENST00000266068 170 gtC/gtT 0 +GMIP UCSF GRCh37 19 19747590 19747590 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 49 57 0 ENST00000203556.4:c.1253C>T p.Thr418Ile p.T418I ENST00000203556 NM_016573.2 418 aCt/aTt 0 +GMIP UCSF GRCh37 19 19746530 19746530 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 68 142 0 ENST00000203556.4:c.1328G>A p.Gly443Asp p.G443D ENST00000203556 NM_016573.2 443 gGc/gAc 0 +GMNC UCSF GRCh37 3 190578610 190578610 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 83 196 0 ENST00000442080.1:c.41G>A p.Gly14Glu p.G14E ENST00000442080 NM_001146686.2 14 gGa/gAa 0 +GMNC UCSF GRCh37 3 190573093 190573093 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 68 138 0 ENST00000442080.1:c.996G>A p.Lys332= p.K332= ENST00000442080 NM_001146686.2 332 aaG/aaA 0 +GNE UCSF GRCh37 9 36249212 36249212 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 101 185 0 ENST00000396594.3:c.234C>T p.Gly78= p.G78= ENST00000396594 NM_001128227.2 78 ggC/ggT 0 +GNL1 UCSF GRCh37 6 30520252 30520252 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 61 102 0 ENST00000376621.3:c.1091G>A p.Gly364Asp p.G364D ENST00000376621 NM_005275.3 364 gGc/gAc 0 +GNPTAB UCSF GRCh37 12 102161819 102161819 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 66 158 0 ENST00000299314.7:c.1404C>T p.Cys468= p.C468= ENST00000299314 NM_024312.4 468 tgC/tgT 0 +GOLGA2 UCSF GRCh37 9 131020399 131020399 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 52 87 0 ENST00000421699.2:c.2287G>A p.Val763Met p.V763M ENST00000421699 NM_004486.4 763 Gtg/Atg 0 +GOLGA2 UCSF GRCh37 9 131021652 131021652 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 17 38 0 ENST00000421699.2:c.1810G>A p.Glu604Lys p.E604K ENST00000421699 NM_004486.4 604 Gag/Aag 0 +GOLGA6D UCSF GRCh37 15 75586567 75586567 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P10_Rec Untested WXS Illumina HiSeq 10 0 ENST00000434739.3:c.1924del p.Gln642ArgfsTer15 p.Q642Rfs*15 ENST00000434739 NM_001145224.1 640 gCc/gc 0 +GOLGB1 UCSF GRCh37 3 121416851 121416851 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 105 229 0 ENST00000393667.3:c.2519G>A p.Ser840Asn p.S840N ENST00000393667 NM_001256486.1 840 aGc/aAc 0 +GOLGB1 UCSF GRCh37 3 121421378 121421378 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 95 220 0 ENST00000393667.3:c.1469G>A p.Gly490Glu p.G490E ENST00000393667 NM_001256486.1 490 gGa/gAa 0 +GOLM1 UCSF GRCh37 9 88661417 88661417 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 12 48 0 ENST00000388712.3:c.435G>A p.Gln145= p.Q145= ENST00000388712 NM_016548.3 145 caG/caA 0 +GOLT1A UCSF GRCh37 1 204172028 204172028 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 38 77 0 ENST00000308302.3:c.113G>A p.Gly38Glu p.G38E ENST00000308302 NM_198447.1 38 gGa/gAa 0 +GPAA1 UCSF GRCh37 8 145140933 145140933 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 229 60 95 0 ENST00000355091.4:c.1771G>A p.Glu591Lys p.E591K ENST00000355091 NM_003801.3 591 Gag/Aag 0 +GPATCH2 UCSF GRCh37 1 217793651 217793651 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 88 167 1 ENST00000366935.3:c.247G>A p.Glu83Lys p.E83K ENST00000366935 NM_018040.2 83 Gag/Aag 0 +GPATCH2 UCSF GRCh37 1 217793830 217793830 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 61 170 0 ENST00000366935.3:c.68G>A p.Arg23Lys p.R23K ENST00000366935 NM_018040.2 23 aGa/aAa 0 +GPATCH8 UCSF GRCh37 17 42477705 42477705 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 55 181 0 ENST00000591680.1:c.1740G>A p.Arg580= p.R580= ENST00000591680 NM_001002909.2 580 agG/agA 0 +GPC1 UCSF GRCh37 2 241401769 241401769 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 5 14 0 ENST00000264039.2:c.487C>T p.Leu163= p.L163= ENST00000264039 NM_002081.2 163 Ctg/Ttg 0 +GPC5 UCSF GRCh37 13 92408593 92408593 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 85 193 0 ENST00000377067.3:c.1199G>A p.Gly400Asp p.G400D ENST00000377067 NM_004466.4 400 gGt/gAt 0 +GPCPD1 UCSF GRCh37 20 5550836 5550836 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 50 121 0 ENST00000379019.4:c.1106C>T p.Pro369Leu p.P369L ENST00000379019 NM_019593.3 369 cCc/cTc 0 +GPNMB UCSF GRCh37 7 23300324 23300324 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 94 207 0 ENST00000381990.2:c.950C>T p.Ala317Val p.A317V ENST00000381990 NM_002510.2 317 gCt/gTt 0 +GPR113 UCSF GRCh37 2 26534114 26534114 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 56 76 0 ENST00000311519.1:c.2482G>A p.Gly828Ser p.G828S ENST00000311519 NM_001145168.1 828 Ggc/Agc 0 +GPR113 UCSF GRCh37 2 26533621 26533621 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 39 100 0 ENST00000311519.1:c.2975C>T p.Thr992Ile p.T992I ENST00000311519 NM_001145168.1 992 aCt/aTt 0 +GPR124 UCSF GRCh37 8 37698907 37698907 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 16 25 0 ENST00000412232.2:c.3051C>T p.Val1017= p.V1017= ENST00000412232 NM_032777.9 1017 gtC/gtT 0 +GPR132 UCSF GRCh37 14 105517706 105517706 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 45 110 0 ENST00000329797.3:c.768C>T p.Ala256= p.A256= ENST00000329797 NM_013345.3 256 gcC/gcT 0 +GPR141 UCSF GRCh37 7 37780399 37780399 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 107 171 0 ENST00000447769.1:c.404C>T p.Ala135Val p.A135V ENST00000447769 135 gCc/gTc 0 +GPR158 UCSF GRCh37 10 25464933 25464933 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 23 49 0 ENST00000376351.3:c.584C>T p.Thr195Met p.T195M ENST00000376351 NM_020752.2 195 aCg/aTg 0 +GPR161 UCSF GRCh37 1 168066189 168066189 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 51 119 0 ENST00000537209.1:c.716C>T p.Ala239Val p.A239V ENST00000537209 NM_001267609.1 239 gCa/gTa 0 +GPR162 UCSF GRCh37 12 6933578 6933578 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 49 79 0 ENST00000311268.3:c.514G>A p.Val172Ile p.V172I ENST00000311268 NM_019858.1 172 Gtc/Atc 0 +GPR179 UCSF GRCh37 17 36485896 36485896 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 131 88 189 0 ENST00000342292.4:c.3556G>A p.Gly1186Ser p.G1186S ENST00000342292 NM_001004334.2 1186 Ggt/Agt 0 +GPR182 UCSF GRCh37 12 57390041 57390041 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 84 173 0 ENST00000300098.1:c.1048G>A p.Ala350Thr p.A350T ENST00000300098 NM_007264.3 350 Gcc/Acc 0 +GPR25 UCSF GRCh37 1 200842190 200842190 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 7 11 0 ENST00000304244.2:c.25C>T p.Pro9Ser p.P9S ENST00000304244 NM_005298.3 9 Ccc/Tcc 0 +GPR26 UCSF GRCh37 10 125447457 125447457 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 49 105 0 ENST00000284674.1:c.795C>T p.Leu265= p.L265= ENST00000284674 NM_153442.3 265 ctC/ctT 0 +GPR44 UCSF GRCh37 11 60620894 60620894 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 14 22 0 ENST00000332539.4:c.302C>T p.Thr101Ile p.T101I ENST00000332539 NM_004778.2 101 aCc/aTc 0 +GPR98 UCSF GRCh37 5 90087119 90087119 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 71 181 0 ENST00000405460.2:c.14473G>A p.Asp4825Asn p.D4825N ENST00000405460 NM_032119.3 4825 Gat/Aat 0 +GPR98 UCSF GRCh37 5 89941817 89941817 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 65 157 0 ENST00000405460.2:c.2931C>T p.Ile977= p.I977= ENST00000405460 NM_032119.3 977 atC/atT 0 +GPRC5D UCSF GRCh37 12 13102939 13102939 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 100 79 177 0 ENST00000228887.1:c.380C>T p.Thr127Met p.T127M ENST00000228887 NM_018654.1 127 aCg/aTg 0 +GPRC5D UCSF GRCh37 12 13103201 13103201 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 65 151 0 ENST00000228887.1:c.118C>T p.Leu40= p.L40= ENST00000228887 NM_018654.1 40 Cta/Tta 0 +GPRIN2 UCSF GRCh37 10 47000217 47000217 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.067,1000g2011may_all_0.1080,snp132_rs72780221 P10_Rec Untested WXS Illumina HiSeq 31 7 21 0 ENST00000374314.4:c.1337G>A p.Arg446His p.R446H ENST00000374314 446 cGc/cAc 0 +GPS1 UCSF GRCh37 17 80013898 80013898 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 28 39 0 ENST00000392358.2:c.976G>A p.Ala326Thr p.A326T ENST00000392358 NM_212492.1 326 Gcc/Acc 0 +GPSM3 UCSF GRCh37 6 32159599 32159599 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 35 65 0 ENST00000375040.3:c.232G>A p.Glu78Lys p.E78K ENST00000375040 NM_001276501.1 78 Gag/Aag 0 +GPSM3 UCSF GRCh37 6 32159654 32159654 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 18 54 0 ENST00000375040.3:c.177C>T p.Ser59= p.S59= ENST00000375040 NM_001276501.1 59 tcC/tcT 0 +GPT UCSF GRCh37 8 145731405 145731405 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 20 57 0 ENST00000394955.2:c.847G>A p.Gly283Ser p.G283S ENST00000394955 NM_005309.2 283 Ggt/Agt 0 +GPX3 UCSF GRCh37 5 150406564 150406564 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 60 121 0 ENST00000388825.4:c.345C>T p.Ile115= p.I115= ENST00000388825 NM_002084.3 115 atC/atT 0 +GRAMD1B UCSF GRCh37 11 123489414 123489414 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 47 133 0 ENST00000529750.1:c.1915G>A p.Val639Ile p.V639I ENST00000529750 NM_020716.1 639 Gtc/Atc 0 +GREB1 UCSF GRCh37 2 11756768 11756768 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 122 112 206 0 ENST00000381486.2:c.3334G>A p.Glu1112Lys p.E1112K ENST00000381486 NM_014668.3 1112 Gag/Aag 0 +GREB1L UCSF GRCh37 18 18981246 18981246 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 68 152 0 ENST00000580732.2:c.668C>T p.Ser223Phe p.S223F ENST00000580732 223 tCc/tTc 0 +GREB1L UCSF GRCh37 18 19079801 19079801 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 54 91 0 ENST00000580732.2:c.3503G>A p.Gly1168Glu p.G1168E ENST00000580732 1168 gGg/gAg 0 +GREB1L UCSF GRCh37 18 19019504 19019504 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 72 155 0 ENST00000580732.2:c.855C>T p.Ser285= p.S285= ENST00000580732 285 agC/agT 0 +GRIA2 UCSF GRCh37 4 158262441 158262441 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 71 180 0 ENST00000296526.7:c.1870G>A p.Gly624Ser p.G624S ENST00000296526 NM_000826.3 624 Ggt/Agt 0 +GRID2 UCSF GRCh37 4 94693496 94693496 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 69 162 0 ENST00000282020.4:c.2871G>A p.Val957= p.V957= ENST00000282020 NM_001510.2 957 gtG/gtA 0 +GRIK2 UCSF GRCh37 6 102124666 102124666 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 44 124 0 ENST00000421544.1:c.710G>A p.Gly237Asp p.G237D ENST00000421544 NM_021956.4 237 gGc/gAc 0 +GRIK3 UCSF GRCh37 1 37271904 37271904 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 30 56 0 ENST00000373091.3:c.2115G>A p.Glu705= p.E705= ENST00000373091 NM_000831.3 705 gaG/gaA 0 +GRIN2B UCSF GRCh37 12 13716834 13716834 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 46 69 0 ENST00000609686.1:c.3338C>T p.Pro1113Leu p.P1113L ENST00000609686 NM_000834.3 1113 cCg/cTg 0 +GRIN2B UCSF GRCh37 12 14018739 14018739 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 110 221 0 ENST00000609686.1:c.404C>T p.Ala135Val p.A135V ENST00000609686 NM_000834.3 135 gCa/gTa 0 +GRIN2D UCSF GRCh37 19 48908291 48908291 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 32 40 0 ENST00000263269.3:c.766G>A p.Val256Met p.V256M ENST00000263269 NM_000836.2 256 Gtg/Atg 0 +GRIN3B UCSF GRCh37 19 1005335 1005335 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 54 100 0 ENST00000234389.3:c.1835C>T p.Thr612Ile p.T612I ENST00000234389 NM_138690.1 612 aCc/aTc 0 +GRINA UCSF GRCh37 8 145066899 145066899 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 161 27 60 0 ENST00000313269.5:c.1006C>T p.Gln336Ter p.Q336* ENST00000313269 NM_000837.1 336 Cag/Tag 0 +GRK5 UCSF GRCh37 10 121207635 121207635 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 57 102 0 ENST00000392870.2:c.1267C>T p.Leu423= p.L423= ENST00000392870 NM_005308.2 423 Ctg/Ttg 0 +GRM3 UCSF GRCh37 7 86394480 86394480 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 101 223 0 ENST00000361669.2:c.19C>T p.Leu7= p.L7= ENST00000361669 NM_000840.2 7 Ctg/Ttg 0 +GRM4 UCSF GRCh37 6 34008508 34008508 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 48 81 0 ENST00000538487.2:c.1186C>T p.Gln396Ter p.Q396* ENST00000538487 NM_000841.2 396 Cag/Tag 0 +GRWD1 UCSF GRCh37 19 48950053 48950053 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 36 78 0 ENST00000253237.5:c.421C>T p.Leu141= p.L141= ENST00000253237 NM_031485.3 141 Ctg/Ttg 0 +GRXCR1 UCSF GRCh37 4 42964927 42964927 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 143 109 220 0 ENST00000399770.2:c.403G>A p.Glu135Lys p.E135K ENST00000399770 NM_001080476.2 135 Gaa/Aaa 0 +GSTCD UCSF GRCh37 4 106766655 106766655 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 57 147 0 ENST00000515279.1:c.1823G>A p.Gly608Glu p.G608E ENST00000515279 608 gGa/gAa 0 +GSTM4 UCSF GRCh37 1 110200394 110200394 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 79 176 0 ENST00000369836.4:c.260G>A p.Cys87Tyr p.C87Y ENST00000369836 NM_000850.4 87 tGt/tAt 0 +GSTO1 UCSF GRCh37 10 106019413 106019413 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 65 145 0 ENST00000369713.5:c.223C>T p.Leu75= p.L75= ENST00000369713 NM_004832.2 75 Ctg/Ttg 0 +GSTT2 UCSF GRCh37 22 24323227 24323227 + splice_donor_variant Splice_Site SNP G G A 1000g2010nov_all_0.153,1000g2011may_all_0.2294,snp132_rs5996646 P10_Rec Untested WXS Illumina HiSeq 62 48 77 0 ENST00000215780.5:c.200+1G>A p.X67_splice ENST00000215780 NM_000854.3 0 +GTDC1 UCSF GRCh37 2 144709586 144709586 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 77 171 0 ENST00000392869.2:c.1256G>A p.Cys419Tyr p.C419Y ENST00000392869 NM_001284234.1 419 tGc/tAc 0 +GTF3C5 UCSF GRCh37 9 135931419 135931419 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 24 68 0 ENST00000372108.5:c.1209G>A p.Arg403= p.R403= ENST00000372108 NM_001122823.1 403 cgG/cgA 0 +GTPBP1 UCSF GRCh37 22 39123237 39123237 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 5 84 150 1 ENST00000216044.5:c.1421G>A p.Arg474Gln p.R474Q ENST00000216044 NM_004286.4 474 cGg/cAg 0 +GTPBP4 UCSF GRCh37 10 1046647 1046647 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 48 103 0 ENST00000360803.4:c.685C>T p.Pro229Ser p.P229S ENST00000360803 NM_012341.2 229 Cct/Tct 0 +GUK1 UCSF GRCh37 1 228336552 228336552 + stop_retained_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 8 21 0 ENST00000366728.2:c.725G>A p.Ter242= p.*242= ENST00000366728 NM_001242840.1 242 tGa/tAa 0 +GZMA UCSF GRCh37 5 54404211 54404211 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 50 147 0 ENST00000274306.6:c.616G>A p.Asp206Asn p.D206N ENST00000274306 NM_006144.3 206 Gac/Aac 0 +HADHB UCSF GRCh37 2 26508395 26508395 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 39 116 0 ENST00000317799.5:c.1345G>A p.Gly449Arg p.G449R ENST00000317799 NM_000183.2 449 Gga/Aga 0 +HAO1 UCSF GRCh37 20 7864306 7864306 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 45 133 0 ENST00000378789.3:c.1047C>T p.Cys349= p.C349= ENST00000378789 NM_017545.2 349 tgC/tgT 0 +HARS2 UCSF GRCh37 5 140076985 140076985 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 53 105 0 ENST00000230771.3:c.1191G>A p.Arg397= p.R397= ENST00000230771 NM_012208.3 397 agG/agA 0 +HAUS5 UCSF GRCh37 19 36104642 36104642 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 35 86 0 ENST00000203166.5:c.109G>A p.Gly37Ser p.G37S ENST00000203166 NM_015302.1 37 Ggc/Agc 0 +HBEGF UCSF GRCh37 5 139722342 139722342 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 121 124 238 0 ENST00000230990.6:c.276G>A p.Gly92= p.G92= ENST00000230990 NM_001945.2 92 ggG/ggA 0 +HCFC1 UCSF GRCh37 X 153215898 153215898 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 55 78 0 ENST00000310441.7:c.5800G>A p.Ala1934Thr p.A1934T ENST00000310441 NM_005334.2 1934 Gct/Act 0 +HCFC1 UCSF GRCh37 X 153228826 153228826 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 63 112 0 ENST00000310441.7:c.562G>A p.Asp188Asn p.D188N ENST00000310441 NM_005334.2 188 Gac/Aac 0 +HCFC1 UCSF GRCh37 X 153217516 153217516 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 10 18 0 ENST00000310441.7:c.5036C>T p.Ala1679Val p.A1679V ENST00000310441 NM_005334.2 1679 gCc/gTc 0 +HCRTR2 UCSF GRCh37 6 55142286 55142286 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 55 129 0 ENST00000370862.3:c.871G>A p.Ala291Thr p.A291T ENST00000370862 NM_001526.3 291 Gct/Act 0 +HDAC1 UCSF GRCh37 1 32793232 32793232 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 52 127 0 ENST00000373548.3:c.590C>T p.Ser197Phe p.S197F ENST00000373548 NM_004964.2 197 tCc/tTc 0 +HDAC2 UCSF GRCh37 6 114274491 114274491 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 108 186 0 ENST00000519065.1:c.589G>A p.Val197Ile p.V197I ENST00000519065 197 Gta/Ata 0 +HDAC4 UCSF GRCh37 2 240024572 240024572 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 33 65 0 ENST00000345617.3:c.2118C>T p.Ala706= p.A706= ENST00000345617 NM_006037.3 706 gcC/gcT 0 +HDAC7 UCSF GRCh37 12 48189160 48189160 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 15 28 0 ENST00000080059.7:c.1091C>T p.Pro364Leu p.P364L ENST00000080059 NM_015401.3 364 cCc/cTc 0 +HDLBP UCSF GRCh37 2 242179450 242179450 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 87 171 0 ENST00000391975.1:c.2257G>A p.Val753Met p.V753M ENST00000391975 NM_203346.3 753 Gtg/Atg 0 +HDX UCSF GRCh37 X 83599315 83599315 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 61 182 0 ENST00000297977.5:c.1603G>A p.Glu535Lys p.E535K ENST00000297977 NM_001177479.1 535 Gag/Aag 0 +HEATR8 UCSF GRCh37 1 55166075 55166075 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 33 52 0 ENST00000414150.2:c.3046C>T p.Pro1016Ser p.P1016S ENST00000414150 1016 Ccc/Tcc 0 +HECA UCSF GRCh37 6 139488196 139488196 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 45 95 1 ENST00000367658.2:c.1047C>T p.Leu349= p.L349= ENST00000367658 NM_016217.2 349 ctC/ctT 0 +HECTD1 UCSF GRCh37 14 31578805 31578805 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 31 72 0 ENST00000399332.1:c.6279-1G>A p.X2093_splice ENST00000399332 NM_015382.2 0 +HECTD1 UCSF GRCh37 14 31617926 31617926 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 46 100 0 ENST00000399332.1:c.2496+1G>A p.X832_splice ENST00000399332 NM_015382.2 0 +HECTD1 UCSF GRCh37 14 31638597 31638597 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 83 208 0 ENST00000399332.1:c.1410G>A p.Arg470= p.R470= ENST00000399332 NM_015382.2 470 agG/agA 0 +HELQ UCSF GRCh37 4 84328662 84328662 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 39 90 0 ENST00000295488.3:c.3250C>T p.Leu1084= p.L1084= ENST00000295488 NM_133636.2 1084 Cta/Tta 0 +HEMGN UCSF GRCh37 9 100689682 100689682 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 143 69 156 0 ENST00000259456.3:c.1439G>A p.Ser480Asn p.S480N ENST00000259456 NM_018437.4 480 aGt/aAt 0 +HEPHL1 UCSF GRCh37 11 93845043 93845043 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 123 204 1 ENST00000315765.9:c.3463C>T p.Pro1155Ser p.P1155S ENST00000315765 NM_001098672.1 1155 Ccc/Tcc 0 +HEPN1 UCSF GRCh37 11 124789666 124789666 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 47 86 0 ENST00000408930.5:c.20G>A p.Gly7Glu p.G7E ENST00000408930 NM_001037558.2 7 gGa/gAa 0 +HERC1 UCSF GRCh37 15 64041674 64041674 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 68 162 0 ENST00000443617.2:c.2111G>A p.Gly704Asp p.G704D ENST00000443617 NM_003922.3 704 gGt/gAt 0 +HERC1 UCSF GRCh37 15 63948464 63948464 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 85 136 0 ENST00000443617.2:c.9693G>A p.Gly3231= p.G3231= ENST00000443617 NM_003922.3 3231 ggG/ggA 0 +HERC1 UCSF GRCh37 15 63915067 63915067 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 21 89 0 ENST00000443617.2:c.13635C>T p.Asp4545= p.D4545= ENST00000443617 NM_003922.3 4545 gaC/gaT 0 +HERC2 UCSF GRCh37 15 28467217 28467217 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 78 228 0 ENST00000261609.7:c.5609G>A p.Gly1870Glu p.G1870E ENST00000261609 NM_004667.5 1870 gGa/gAa 0 +HERC2 UCSF GRCh37 15 28389922 28389922 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 49 89 0 ENST00000261609.7:c.11037G>A p.Glu3679= p.E3679= ENST00000261609 NM_004667.5 3679 gaG/gaA 0 +HEXDC UCSF GRCh37 17 80393661 80393661 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 50 78 0 ENST00000337014.6:c.544G>A p.Ala182Thr p.A182T ENST00000337014 NM_173620.2 182 Gcc/Acc 0 +HEXDC UCSF GRCh37 17 80400336 80400336 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 41 81 0 ENST00000337014.6:c.1626G>A p.Arg542= p.R542= ENST00000337014 NM_173620.2 542 cgG/cgA 0 +HHAT UCSF GRCh37 1 210591662 210591662 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 54 137 0 ENST00000545154.1:c.852G>A p.Trp284Ter p.W284* ENST00000545154 NM_001170587.1 284 tgG/tgA 0 +HHIPL2 UCSF GRCh37 1 222717259 222717259 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 96 0 ENST00000343410.6:c.594C>T p.Ala198= p.A198= ENST00000343410 NM_024746.3 198 gcC/gcT 0 +HHLA1 UCSF GRCh37 8 133088376 133088376 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 23 38 0 ENST00000434736.2:c.1349G>A p.Gly450Asp p.G450D ENST00000434736 450 gGt/gAt 0 +HIBCH UCSF GRCh37 2 191125913 191125913 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 56 159 0 ENST00000359678.5:c.486G>A p.Lys162= p.K162= ENST00000359678 NM_198047.2 162 aaG/aaA 0 +HIF1A UCSF GRCh37 14 62194253 62194253 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 68 178 0 ENST00000539097.1:c.725C>T p.Thr242Ile p.T242I ENST00000539097 NM_001243084.1 242 aCc/aTc 0 +HIF3A UCSF GRCh37 19 46811518 46811518 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 40 136 0 ENST00000377670.4:c.404C>T p.Pro135Leu p.P135L ENST00000377670 NM_152795.3 135 cCc/cTc 0 +HIP1 UCSF GRCh37 7 75221383 75221383 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 79 151 0 ENST00000336926.6:c.375C>T p.Ser125= p.S125= ENST00000336926 NM_005338.6 125 agC/agT 0 +HIPK1 UCSF GRCh37 1 114499778 114499778 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 65 160 0 ENST00000369558.1:c.1625G>A p.Cys542Tyr p.C542Y ENST00000369558 542 tGc/tAc 0 +HIPK1 UCSF GRCh37 1 114499776 114499776 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 67 161 0 ENST00000369558.1:c.1623C>T p.Ile541= p.I541= ENST00000369558 541 atC/atT 0 +HIST1H2BC UCSF GRCh37 6 26123872 26123872 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 84 177 0 ENST00000314332.5:c.261C>T p.Arg87= p.R87= ENST00000314332 87 cgC/cgT 0 +HIVEP3 UCSF GRCh37 1 42047716 42047716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 74 141 0 ENST00000372583.1:c.2753G>A p.Gly918Glu p.G918E ENST00000372583 NM_024503.4 918 gGg/gAg 0 +HJURP UCSF GRCh37 2 234750489 234750489 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 71 128 0 ENST00000411486.2:c.937G>A p.Ala313Thr p.A313T ENST00000411486 NM_018410.3 313 Gcc/Acc 0 +HJURP UCSF GRCh37 2 234754383 234754383 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 54 128 0 ENST00000411486.2:c.486G>A p.Glu162= p.E162= ENST00000411486 NM_018410.3 162 gaG/gaA 0 +HLA-G UCSF GRCh37 6 29795629 29795629 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 43 20 83 0 ENST00000428701.1:c.8T>C p.Val3Ala p.V3A ENST00000428701 NM_002127.5 3 gTc/gCc 0 +HMBS UCSF GRCh37 11 118963857 118963857 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 62 126 0 ENST00000278715.3:c.950G>A p.Gly317Asp p.G317D ENST00000278715 NM_000190.3 317 gGc/gAc 0 +HMCN1 UCSF GRCh37 1 186134277 186134277 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 52 118 0 ENST00000271588.4:c.15291C>T p.Thr5097= p.T5097= ENST00000271588 NM_031935.2 5097 acC/acT 0 +HMGCLL1 UCSF GRCh37 6 55360216 55360216 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 35 149 0 ENST00000398661.2:c.885+1G>A p.X295_splice ENST00000398661 NM_019036.2 0 +HMHA1 UCSF GRCh37 19 1083224 1083224 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 12 0 ENST00000539243.2:c.2875C>T p.Pro959Ser p.P959S ENST00000539243 NM_001258328.1 959 Ccc/Tcc 0 +HMX3 UCSF GRCh37 10 124896686 124896686 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 11 31 0 ENST00000357878.5:c.513C>T p.Ser171= p.S171= ENST00000357878 NM_001105574.1 171 agC/agT 0 +HNF4G UCSF GRCh37 8 76463725 76463725 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 45 101 0 ENST00000396423.2:c.455G>A p.Arg152His p.R152H ENST00000396423 NM_004133.4 152 cGc/cAc 0 +HNRNPA1 UCSF GRCh37 12 54678084 54678084 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 62 164 0 ENST00000340913.6:c.1106G>A p.Gly369Asp p.G369D ENST00000340913 NM_002136.2 369 gGc/gAc 0 +HNRNPU UCSF GRCh37 1 245026995 245026995 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 10 12 0 ENST00000283179.9:c.615G>A p.Gln205= p.Q205= ENST00000283179 205 caG/caA 0 +HNRNPUL2 UCSF GRCh37 11 62483026 62483026 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 64 137 0 ENST00000301785.5:c.2109G>A p.Gly703= p.G703= ENST00000301785 NM_001079559.2 703 ggG/ggA 0 +HNRNPUL2 UCSF GRCh37 11 62487502 62487502 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 84 144 0 ENST00000301785.5:c.1773G>A p.Glu591= p.E591= ENST00000301785 NM_001079559.2 591 gaG/gaA 0 +HOMEZ UCSF GRCh37 14 23745503 23745503 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 95 196 0 ENST00000357460.5:c.934G>A p.Val312Ile p.V312I ENST00000357460 NM_020834.2 312 Gtc/Atc 0 +HOMEZ UCSF GRCh37 14 23745147 23745147 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 116 105 176 0 ENST00000357460.5:c.1290C>T p.Phe430= p.F430= ENST00000357460 NM_020834.2 430 ttC/ttT 0 +HOXA5 UCSF GRCh37 7 27182773 27182773 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 29 63 0 ENST00000222726.3:c.454G>A p.Asp152Asn p.D152N ENST00000222726 NM_019102.3 152 Gac/Aac 0 +HOXB3 UCSF GRCh37 17 46627775 46627775 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 19 52 0 ENST00000470495.1:c.1217C>T p.Thr406Ile p.T406I ENST00000470495 406 aCc/aTc 0 +HOXC9 UCSF GRCh37 12 54396377 54396377 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 70 177 0 ENST00000303450.4:c.702G>A p.Arg234= p.R234= ENST00000303450 NM_006897.1 234 cgG/cgA 0 +HOXD12 UCSF GRCh37 2 176964675 176964675 + missense_variant Missense_Mutation SNP T T G NOVEL P10_Rec Untested WXS Illumina HiSeq 39 32 57 1 ENST00000406506.2:c.146T>G p.Leu49Arg p.L49R ENST00000406506 49 cTg/cGg 0 +HPCAL4 UCSF GRCh37 1 40149716 40149716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 16 51 0 ENST00000372844.3:c.271G>A p.Val91Ile p.V91I ENST00000372844 NM_016257.2 91 Gtc/Atc 0 +HR UCSF GRCh37 8 21977951 21977951 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 48 78 0 ENST00000381418.4:c.2680C>T p.Leu894Phe p.L894F ENST00000381418 NM_005144.4 894 Ctt/Ttt 0 +HRC UCSF GRCh37 19 49656719 49656719 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 23 42 0 ENST00000252825.4:c.1776C>T p.Asp592= p.D592= ENST00000252825 NM_002152.2 592 gaC/gaT 0 +HRNR UCSF GRCh37 1 152185889 152185889 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 8 25 0 ENST00000368801.2:c.8216G>A p.Ser2739Asn p.S2739N ENST00000368801 NM_001009931.2 2739 aGc/aAc 0 +HRNR UCSF GRCh37 1 152191061 152191061 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 98 263 0 ENST00000368801.2:c.3044G>A p.Gly1015Glu p.G1015E ENST00000368801 NM_001009931.2 1015 gGg/gAg 0 +HRNR UCSF GRCh37 1 152188064 152188064 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 488 73 912 0 ENST00000368801.2:c.6041C>T p.Ser2014Phe p.S2014F ENST00000368801 NM_001009931.2 2014 tCt/tTt 0 +HRNR UCSF GRCh37 1 152193068 152193068 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 111 207 0 ENST00000368801.2:c.1037C>T p.Ser346Phe p.S346F ENST00000368801 NM_001009931.2 346 tCt/tTt 0 +HS3ST3A1 UCSF GRCh37 17 13400067 13400067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 42 124 0 ENST00000284110.1:c.668G>A p.Arg223Gln p.R223Q ENST00000284110 NM_006042.1 223 cGg/cAg 0 +HS3ST3B1 UCSF GRCh37 17 14248413 14248413 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 1 38 46 0 ENST00000360954.2:c.623G>A p.Arg208Gln p.R208Q ENST00000360954 NM_006041.1 208 cGg/cAg 0 +HS3ST4 UCSF GRCh37 16 25704412 25704412 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 19 42 0 ENST00000331351.5:c.674C>T p.Ala225Val p.A225V ENST00000331351 NM_006040.2 225 gCg/gTg 0 +HSD11B2 UCSF GRCh37 16 67470844 67470844 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 26 72 0 ENST00000326152.5:c.1156C>T p.Pro386Ser p.P386S ENST00000326152 NM_000196.3 386 Cca/Tca 0 +HSDL1 UCSF GRCh37 16 84158330 84158330 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 41 84 0 ENST00000219439.4:c.898C>T p.Leu300Phe p.L300F ENST00000219439 NM_001146051.1 300 Ctt/Ttt 0 +HSF1 UCSF GRCh37 8 145533197 145533197 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 185 43 102 0 ENST00000528838.1:c.283G>A p.Asp95Asn p.D95N ENST00000528838 NM_005526.2 95 Gac/Aac 0 +HSPA14 UCSF GRCh37 10 14890607 14890607 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 37 108 0 ENST00000378372.3:c.222-1G>A p.X74_splice ENST00000378372 NM_016299.3 0 +HSPA1A UCSF GRCh37 6 31783580 31783580 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 34 87 0 ENST00000375651.5:c.47C>T p.Ser16Phe p.S16F ENST00000375651 NM_005345.5 16 tCc/tTc 0 +HSPA5 UCSF GRCh37 9 128001393 128001393 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 168 72 146 0 ENST00000324460.6:c.823G>A p.Gly275Ser p.G275S ENST00000324460 NM_005347.4 275 Ggc/Agc 0 +HSPA5 UCSF GRCh37 9 128001379 128001379 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 156 77 144 0 ENST00000324460.6:c.837G>A p.Arg279= p.R279= ENST00000324460 NM_005347.4 279 agG/agA 0 +HSPG2 UCSF GRCh37 1 22206914 22206914 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 32 54 0 ENST00000374695.3:c.2137G>A p.Asp713Asn p.D713N ENST00000374695 NM_005529.5 713 Gat/Aat 0 +HSPG2 UCSF GRCh37 1 22202774 22202774 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 20 9 23 0 ENST00000374695.3:c.2951T>C p.Leu984Pro p.L984P ENST00000374695 NM_005529.5 984 cTc/cCc 0 +HTATSF1 UCSF GRCh37 X 135592333 135592333 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 117 243 0 ENST00000535601.1:c.1017C>T p.Gly339= p.G339= ENST00000535601 NM_001163280.1 339 ggC/ggT 0 +HTR3A UCSF GRCh37 11 113853846 113853846 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 62 152 0 ENST00000355556.2:c.397G>A p.Asp133Asn p.D133N ENST00000355556 NM_213621.3 133 Gat/Aat 0 +HTRA1 UCSF GRCh37 10 124248504 124248504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 54 132 0 ENST00000368984.3:c.559G>A p.Glu187Lys p.E187K ENST00000368984 NM_002775.4 187 Gaa/Aaa 0 +HTT UCSF GRCh37 4 3144503 3144503 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 84 141 0 ENST00000355072.5:c.2956G>A p.Gly986Ser p.G986S ENST00000355072 NM_002111.6 986 Ggc/Agc 0 +HUWE1 UCSF GRCh37 X 53591615 53591615 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 59 133 0 ENST00000342160.3:c.6949G>A p.Asp2317Asn p.D2317N ENST00000342160 2317 Gat/Aat 0 +HUWE1 UCSF GRCh37 X 53563380 53563380 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 66 231 0 ENST00000342160.3:c.12386C>T p.Thr4129Ile p.T4129I ENST00000342160 4129 aCt/aTt 0 +HUWE1 UCSF GRCh37 X 53566032 53566032 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 18 52 0 ENST00000342160.3:c.11642C>T p.Pro3881Leu p.P3881L ENST00000342160 3881 cCt/cTt 0 +HYAL2 UCSF GRCh37 3 50357097 50357097 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 34 53 0 ENST00000447092.1:c.824C>T p.Ala275Val p.A275V ENST00000447092 275 gCc/gTc 0 +HYDIN UCSF GRCh37 16 70989284 70989284 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 211 69 265 0 ENST00000393567.2:c.6310G>A p.Glu2104Lys p.E2104K ENST00000393567 NM_001270974.1 2104 Gag/Aag 0 +HYDIN UCSF GRCh37 16 71061635 71061635 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 196 56 254 0 ENST00000393567.2:c.2912C>T p.Pro971Leu p.P971L ENST00000393567 NM_001270974.1 971 cCc/cTc 0 +HYOU1 UCSF GRCh37 11 118924874 118924874 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 70 143 0 ENST00000404233.3:c.753G>A p.Lys251= p.K251= ENST00000404233 NM_001130991.1 251 aaG/aaA 0 +IARS2 UCSF GRCh37 1 220300096 220300096 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 67 146 0 ENST00000302637.5:c.1748G>A p.Gly583Asp p.G583D ENST00000302637 NM_018060.3 583 gGt/gAt 0 +IBA57 UCSF GRCh37 1 228363087 228363087 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 59 130 0 ENST00000366711.3:c.944G>A p.Gly315Asp p.G315D ENST00000366711 NM_001010867.2 315 gGc/gAc 0 +IBTK UCSF GRCh37 6 82935319 82935319 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 62 143 2 ENST00000306270.7:c.700G>A p.Val234Met p.V234M ENST00000306270 NM_015525.2 234 Gtg/Atg 0 +ICAM1 UCSF GRCh37 19 10395520 10395520 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 39 81 0 ENST00000264832.3:c.1242G>A p.Gln414= p.Q414= ENST00000264832 NM_000201.2 414 caG/caA 0 +ICAM2 UCSF GRCh37 17 62082531 62082531 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 50 100 0 ENST00000412356.1:c.264C>T p.Val88= p.V88= ENST00000412356 NM_001099786.1 88 gtC/gtT 0 +ICAM3 UCSF GRCh37 19 10445447 10445447 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 32 84 0 ENST00000160262.5:c.949C>T p.Pro317Ser p.P317S ENST00000160262 NM_002162.3 317 Ccc/Tcc 0 +ICMT UCSF GRCh37 1 6292032 6292032 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 64 154 0 ENST00000343813.5:c.602C>T p.Thr201Ile p.T201I ENST00000343813 NM_012405.3 201 aCc/aTc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 79 72 125 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IDO1 UCSF GRCh37 8 39775667 39775667 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 112 192 0 ENST00000518237.1:c.244G>A p.Val82Ile p.V82I ENST00000518237 NM_002164.5 82 Gtt/Att 0 +IFFO2 UCSF GRCh37 1 19235148 19235148 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 31 85 0 ENST00000455833.2:c.1461C>T p.Ser487= p.S487= ENST00000455833 NM_001136265.1 487 tcC/tcT 0 +IFI27L1 UCSF GRCh37 14 94568225 94568225 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 35 68 0 ENST00000555523.1:c.127G>A p.Ala43Thr p.A43T ENST00000555523 NM_206949.2 43 Gca/Aca 0 +IFIH1 UCSF GRCh37 2 163144827 163144827 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 56 119 0 ENST00000263642.2:c.913G>A p.Glu305Lys p.E305K ENST00000263642 NM_022168.3 305 Gaa/Aaa 0 +IFIT3 UCSF GRCh37 10 91098440 91098440 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 47 131 1 ENST00000371818.4:c.28G>A p.Glu10Lys p.E10K ENST00000371818 NM_001549.4 10 Gag/Aag 0 +IFITM1 UCSF GRCh37 11 314971 314971 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 44 132 0 ENST00000408968.3:c.236C>T p.Ala79Val p.A79V ENST00000408968 NM_003641.3 79 gCc/gTc 0 +IFNAR2 UCSF GRCh37 21 34635734 34635734 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 96 166 0 ENST00000342136.4:c.1477G>A p.Asp493Asn p.D493N ENST00000342136 493 Gat/Aat 0 +IFNGR1 UCSF GRCh37 6 137519586 137519586 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 60 156 0 ENST00000367739.4:c.1052G>A p.Ser351Asn p.S351N ENST00000367739 NM_000416.2 351 aGt/aAt 0 +IFT122 UCSF GRCh37 3 129202342 129202342 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 52 117 0 ENST00000296266.3:c.1821C>T p.Asn607= p.N607= ENST00000296266 NM_052985.3 607 aaC/aaT 0 +IFT140 UCSF GRCh37 16 1614105 1614105 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 38 99 0 ENST00000426508.2:c.1960G>A p.Asp654Asn p.D654N ENST00000426508 NM_014714.3 654 Gac/Aac 0 +IFT172 UCSF GRCh37 2 27677249 27677249 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 79 152 0 ENST00000260570.3:c.3502G>A p.Ala1168Thr p.A1168T ENST00000260570 NM_015662.1 1168 Gct/Act 0 +IGSF6 UCSF GRCh37 16 21658659 21658659 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 70 133 0 ENST00000268389.4:c.222G>A p.Gln74= p.Q74= ENST00000268389 NM_005849.3 74 caG/caA 0 +IGSF8 UCSF GRCh37 1 160065004 160065004 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 35 63 0 ENST00000368086.1:c.97C>T p.Pro33Ser p.P33S ENST00000368086 33 Ccc/Tcc 0 +IKBKE UCSF GRCh37 1 206664992 206664992 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 50 109 0 ENST00000367120.3:c.1745G>A p.Ser582Asn p.S582N ENST00000367120 NM_014002.3 582 aGt/aAt 0 +IKBKG UCSF GRCh37 X 153780245 153780245 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 83 170 0 ENST00000369609.5:c.232C>T p.Leu78= p.L78= ENST00000369609 NM_001099856.2 78 Ctg/Ttg 0 +IKZF5 UCSF GRCh37 10 124753348 124753349 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 0 ENST00000368886.5:c.1208dup p.Asn403LysfsTer4 p.N403Kfs*4 ENST00000368886 NM_001271840.1 403 aac/aAac 0 +IL11RA UCSF GRCh37 9 34657129 34657129 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 75 122 0 ENST00000555003.1:c.429C>T p.Arg143= p.R143= ENST00000555003 143 cgC/cgT 0 +IL12RB2 UCSF GRCh37 1 67794023 67794023 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 123 212 0 ENST00000262345.1:c.620G>A p.Gly207Glu p.G207E ENST00000262345 NM_001559.2 207 gGa/gAa 0 +IL17RC UCSF GRCh37 3 9974353 9974353 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 103 1 ENST00000295981.3:c.1662C>T p.Ser554= p.S554= ENST00000295981 NM_153461.3 554 tcC/tcT 0 +IL17RD UCSF GRCh37 3 57136581 57136581 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 55 94 0 ENST00000296318.7:c.905C>T p.Ala302Val p.A302V ENST00000296318 NM_017563.3 302 gCc/gTc 0 +IL18RAP UCSF GRCh37 2 103068538 103068538 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 100 239 0 ENST00000264260.2:c.1697G>A p.Gly566Glu p.G566E ENST00000264260 NM_003853.2 566 gGa/gAa 0 +IL1A UCSF GRCh37 2 113537213 113537213 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 66 142 0 ENST00000263339.3:c.350G>A p.Ser117Asn p.S117N ENST00000263339 NM_000575.3 117 aGc/aAc 0 +IL1RAP UCSF GRCh37 3 190326971 190326971 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 46 113 0 ENST00000317757.3:c.537+1G>A p.X179_splice ENST00000317757 NM_001167931.1 0 +IL1RAPL2 UCSF GRCh37 X 104993017 104993017 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 77 180 0 ENST00000372582.1:c.1113G>A p.Leu371= p.L371= ENST00000372582 NM_017416.1 371 ctG/ctA 0 +IL1RL2 UCSF GRCh37 2 102804367 102804367 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 38 73 0 ENST00000264257.2:c.40C>T p.Pro14Ser p.P14S ENST00000264257 NM_003854.2 14 Cca/Tca 0 +IL21R UCSF GRCh37 16 27448847 27448847 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 53 85 0 ENST00000337929.3:c.191C>T p.Ser64Phe p.S64F ENST00000337929 NM_181078.2 64 tCc/tTc 0 +IL21R UCSF GRCh37 16 27457348 27457348 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 20 61 0 ENST00000337929.3:c.806C>T p.Ala269Val p.A269V ENST00000337929 NM_181078.2 269 gCc/gTc 0 +IL21R UCSF GRCh37 16 27460404 27460404 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 42 57 0 ENST00000337929.3:c.1417G>A p.Val473Ile p.V473I ENST00000337929 NM_181078.2 473 Gtc/Atc 0 +IL23R UCSF GRCh37 1 67724311 67724311 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 101 206 0 ENST00000347310.5:c.1390C>T p.Pro464Ser p.P464S ENST00000347310 NM_144701.2 464 Ccg/Tcg 0 +IL24 UCSF GRCh37 1 207072856 207072856 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 46 112 0 ENST00000391929.3:c.239C>T p.Thr80Ile p.T80I ENST00000391929 80 aCt/aTt 0 +IL29 UCSF GRCh37 19 39787105 39787105 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 51 101 0 ENST00000333625.2:c.44G>A p.Gly15Asp p.G15D ENST00000333625 NM_172140.1 15 gGc/gAc 0 +IL2RG UCSF GRCh37 X 70330757 70330757 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 10 56 0 ENST00000374202.2:c.259C>T p.Leu87= p.L87= ENST00000374202 NM_000206.2 87 Ctg/Ttg 0 +IL4R UCSF GRCh37 16 27374306 27374306 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 65 100 0 ENST00000395762.2:c.1633C>T p.Pro545Ser p.P545S ENST00000395762 NM_000418.3 545 Cct/Tct 0 +ILDR1 UCSF GRCh37 3 121713086 121713086 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 34 56 0 ENST00000344209.5:c.721G>A p.Gly241Arg p.G241R ENST00000344209 NM_001199799.1 241 Ggg/Agg 0 +ILF3 UCSF GRCh37 19 10781781 10781781 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 33 76 0 ENST00000449870.1:c.135G>A p.Val45= p.V45= ENST00000449870 NM_017620.2 45 gtG/gtA 0 +IMP5 UCSF GRCh37 17 43923859 43923859 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 41 106 0 ENST00000329196.5:c.1587G>A p.Gln529= p.Q529= ENST00000329196 NM_175882.2 529 caG/caA 0 +INADL UCSF GRCh37 1 62579725 62579725 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 39 89 0 ENST00000371158.2:c.4462G>A p.Val1488Ile p.V1488I ENST00000371158 NM_176877.2 1488 Gtt/Att 0 +ING1 UCSF GRCh37 13 111371609 111371609 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 32 86 0 ENST00000375774.3:c.599G>A p.Arg200His p.R200H ENST00000375774 NM_005537.4 200 cGc/cAc 0 +INPP4A UCSF GRCh37 2 99152264 99152264 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 108 231 0 ENST00000074304.5:c.343G>A p.Val115Ile p.V115I ENST00000074304 NM_001134224.1 115 Gtc/Atc 0 +INPP5E UCSF GRCh37 9 139333207 139333207 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 11 29 0 ENST00000371712.3:c.665G>A p.Arg222His p.R222H ENST00000371712 NM_019892.4 222 cGc/cAc 0 +INSR UCSF GRCh37 19 7117094 7117094 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 80 149 0 ENST00000302850.5:c.4122G>A p.Leu1374= p.L1374= ENST00000302850 NM_000208.2 1374 ctG/ctA 0 +INSRR UCSF GRCh37 1 156814407 156814407 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 49 85 0 ENST00000368195.3:c.2584G>A p.Val862Met p.V862M ENST00000368195 NM_014215.2 862 Gtg/Atg 0 +INTS10 UCSF GRCh37 8 19703296 19703296 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 43 87 0 ENST00000397977.3:c.1964G>A p.Gly655Glu p.G655E ENST00000397977 NM_018142.2 655 gGa/gAa 0 +INTS3 UCSF GRCh37 1 153745692 153745692 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 130 107 211 0 ENST00000318967.2:c.3075G>A p.Lys1025= p.K1025= ENST00000318967 NM_023015.3 1025 aaG/aaA 0 +INTS5 UCSF GRCh37 11 62416972 62416972 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 76 123 0 ENST00000330574.2:c.580G>A p.Val194Met p.V194M ENST00000330574 NM_030628.1 194 Gtg/Atg 0 +INTS7 UCSF GRCh37 1 212180717 212180717 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 55 121 0 ENST00000366994.3:c.631G>A p.Ala211Thr p.A211T ENST00000366994 NM_001199811.1 211 Gct/Act 0 +INTS8 UCSF GRCh37 8 95877891 95877891 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 404 109 238 0 ENST00000523731.1:c.2234G>A p.Arg745Lys p.R745K ENST00000523731 NM_017864.3 745 aGg/aAg 0 +INTU UCSF GRCh37 4 128565143 128565143 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 83 176 0 ENST00000335251.6:c.614G>A p.Gly205Glu p.G205E ENST00000335251 NM_015693.3 205 gGa/gAa 0 +INTU UCSF GRCh37 4 128564907 128564907 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 78 178 0 ENST00000335251.6:c.378G>A p.Lys126= p.K126= ENST00000335251 NM_015693.3 126 aaG/aaA 0 +INTU UCSF GRCh37 4 128628070 128628070 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 124 101 230 0 ENST00000335251.6:c.2217G>A p.Lys739= p.K739= ENST00000335251 NM_015693.3 739 aaG/aaA 0 +IP6K3 UCSF GRCh37 6 33695944 33695944 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 39 47 0 ENST00000451316.1:c.333G>A p.Gln111= p.Q111= ENST00000451316 NM_001142883.1 111 caG/caA 0 +IPCEF1 UCSF GRCh37 6 154533945 154533945 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 23 85 0 ENST00000422970.2:c.496G>A p.Glu166Lys p.E166K ENST00000422970 NM_001130699.1 166 Gag/Aag 0 +IPO8 UCSF GRCh37 12 30787141 30787141 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 69 163 0 ENST00000256079.4:c.2775G>A p.Glu925= p.E925= ENST00000256079 NM_006390.3 925 gaG/gaA 0 +IQCH UCSF GRCh37 15 67636400 67636400 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 52 125 0 ENST00000335894.4:c.509-1G>A p.X170_splice ENST00000335894 NM_001031715.2 0 +IQGAP1 UCSF GRCh37 15 91017362 91017362 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 47 114 0 ENST00000268182.5:c.2572C>T p.Leu858Phe p.L858F ENST00000268182 NM_003870.3 858 Ctc/Ttc 0 +IQGAP1 UCSF GRCh37 15 91017182 91017182 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 68 173 0 ENST00000268182.5:c.2488C>T p.Gln830Ter p.Q830* ENST00000268182 NM_003870.3 830 Cag/Tag 0 +IQSEC2 UCSF GRCh37 X 53279582 53279582 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 45 96 0 ENST00000396435.3:c.2176G>A p.Ala726Thr p.A726T ENST00000396435 NM_001111125.2 726 Gct/Act 0 +IQSEC2 UCSF GRCh37 X 53279927 53279927 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 14 26 0 ENST00000396435.3:c.1831G>A p.Asp611Asn p.D611N ENST00000396435 NM_001111125.2 611 Gat/Aat 0 +IRF5 UCSF GRCh37 7 128588798 128588798 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 57 115 0 ENST00000357234.5:c.1471G>A p.Ala491Thr p.A491T ENST00000357234 491 Gcc/Acc 0 +IRS1 UCSF GRCh37 2 227663202 227663202 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 73 121 0 ENST00000305123.5:c.253G>A p.Ala85Thr p.A85T ENST00000305123 NM_005544.2 85 Gct/Act 0 +IRX3 UCSF GRCh37 16 54319241 54319241 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 52 89 0 ENST00000329734.3:c.552C>T p.Arg184= p.R184= ENST00000329734 NM_024336.2 184 cgC/cgT 0 +ISLR UCSF GRCh37 15 74468085 74468085 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 42 87 0 ENST00000249842.3:c.886C>T p.Pro296Ser p.P296S ENST00000249842 NM_005545.3 296 Cct/Tct 0 +ITGA2 UCSF GRCh37 5 52377511 52377511 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 31 70 0 ENST00000296585.5:c.3129G>A p.Arg1043= p.R1043= ENST00000296585 NM_002203.3 1043 agG/agA 0 +ITGA2B UCSF GRCh37 17 42466653 42466653 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 99 195 0 ENST00000262407.5:c.188+1G>A p.X63_splice ENST00000262407 NM_000419.3 0 +ITGA6 UCSF GRCh37 2 173338860 173338860 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 41 112 0 ENST00000409080.1:c.853C>T p.His285Tyr p.H285Y ENST00000409080 NM_001079818.1 285 Cac/Tac 0 +ITGA6 UCSF GRCh37 2 173292620 173292620 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 13 45 0 ENST00000409080.1:c.104G>A p.Arg35Gln p.R35Q ENST00000409080 NM_001079818.1 35 cGg/cAg 0 +ITGA8 UCSF GRCh37 10 15573138 15573138 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 130 67 140 0 ENST00000378076.3:c.2893C>T p.Pro965Ser p.P965S ENST00000378076 NM_003638.1 965 Ccc/Tcc 0 +ITGAD UCSF GRCh37 16 31409192 31409192 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 8 26 1 ENST00000389202.2:c.389G>A p.Arg130His p.R130H ENST00000389202 NM_005353.2 130 cGc/cAc 0 +ITGB3 UCSF GRCh37 17 45376743 45376743 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 54 108 0 ENST00000559488.1:c.1760C>T p.Thr587Ile p.T587I ENST00000559488 NM_000212.2 587 aCc/aTc 0 +ITGB3 UCSF GRCh37 17 45369919 45369919 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 55 130 0 ENST00000559488.1:c.1675G>A p.Gly559Arg p.G559R ENST00000559488 NM_000212.2 559 Ggg/Agg 0 +ITIH5 UCSF GRCh37 10 7683969 7683969 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 199 92 185 0 ENST00000256861.6:c.220C>T p.Leu74= p.L74= ENST00000256861 NM_030569.6 74 Ctg/Ttg 0 +ITPK1 UCSF GRCh37 14 93418312 93418312 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 8 17 0 ENST00000267615.6:c.717G>A p.Glu239= p.E239= ENST00000267615 239 gaG/gaA 0 +ITPR1 UCSF GRCh37 3 4725105 4725105 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 140 106 227 0 ENST00000302640.8:c.3152G>A p.Gly1051Asp p.G1051D ENST00000302640 NM_001168272.1 1051 gGc/gAc 0 +ITPR2 UCSF GRCh37 12 26775262 26775262 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 46 116 0 ENST00000381340.3:c.3199C>T p.His1067Tyr p.H1067Y ENST00000381340 NM_002223.2 1067 Cac/Tac 0 +ITPR3 UCSF GRCh37 6 33639817 33639817 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 38 106 0 ENST00000374316.5:c.2740C>T p.Arg914Trp p.R914W ENST00000374316 914 Cgg/Tgg 0 +ITPR3 UCSF GRCh37 6 33646227 33646227 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 21 64 0 ENST00000374316.5:c.3678C>T p.Arg1226= p.R1226= ENST00000374316 1226 cgC/cgT 0 +ITPRIP UCSF GRCh37 10 106074458 106074458 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 37 86 0 ENST00000278071.2:c.1352C>T p.Ala451Val p.A451V ENST00000278071 NM_033397.3 451 gCg/gTg 0 +ITPRIPL1 UCSF GRCh37 2 96993035 96993035 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 54 125 0 ENST00000361124.4:c.690C>T p.Ala230= p.A230= ENST00000361124 NM_178495.5 230 gcC/gcT 0 +IVNS1ABP UCSF GRCh37 1 185276206 185276206 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 59 163 0 ENST00000367498.3:c.597C>T p.Ile199= p.I199= ENST00000367498 NM_006469.4 199 atC/atT 0 +JHDM1D UCSF GRCh37 7 139829311 139829311 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 64 133 0 ENST00000397560.2:c.541G>A p.Asp181Asn p.D181N ENST00000397560 NM_030647.1 181 Gat/Aat 0 +JMJD1C UCSF GRCh37 10 64974231 64974231 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 83 159 0 ENST00000399262.2:c.1696G>A p.Val566Ile p.V566I ENST00000399262 NM_032776.1 566 Gtc/Atc 0 +JPH2 UCSF GRCh37 20 42744429 42744429 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 20 56 0 ENST00000372980.3:c.1886C>T p.Pro629Leu p.P629L ENST00000372980 NM_020433.4 629 cCc/cTc 0 +JPH3 UCSF GRCh37 16 87677922 87677922 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 11 84 0 ENST00000284262.2:c.441C>T p.Ser147= p.S147= ENST00000284262 NM_020655.3 147 agC/agT 0 +JRK UCSF GRCh37 8 143740347 143740347 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 20 64 0 ENST00000507178.2:n.7464G>A *2488* ENST00000507178 0 +KALRN UCSF GRCh37 3 124418823 124418823 + upstream_gene_variant 5'Flank SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 85 200 0 ENST00000584173 0 +KALRN UCSF GRCh37 3 124117637 124117637 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 64 131 0 ENST00000240874.3:c.2259G>A p.Gln753= p.Q753= ENST00000240874 NM_003947.4 753 caG/caA 0 +KANK3 UCSF GRCh37 19 8398051 8398051 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 10 29 0 ENST00000330915.3:c.1783G>A p.Glu595Lys p.E595K ENST00000330915 NM_198471.2 595 Gag/Aag 0 +KBTBD4 UCSF GRCh37 11 47598997 47598997 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 76 149 0 ENST00000430070.2:c.603C>T p.His201= p.H201= ENST00000430070 NM_018095.4 201 caC/caT 0 +KCNA3 UCSF GRCh37 1 111216551 111216551 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 47 118 0 ENST00000369769.2:c.881C>T p.Pro294Leu p.P294L ENST00000369769 NM_002232.3 294 cCc/cTc 0 +KCNC1 UCSF GRCh37 11 17757750 17757750 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 27 70 0 ENST00000265969.6:c.201C>T p.Ile67= p.I67= ENST00000265969 NM_001112741.1 67 atC/atT 0 +KCNH4 UCSF GRCh37 17 40318550 40318550 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 34 83 0 ENST00000264661.3:c.1605C>T p.Phe535= p.F535= ENST00000264661 NM_012285.2 535 ttC/ttT 0 +KCNH5 UCSF GRCh37 14 63246594 63246594 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 58 116 0 ENST00000322893.7:c.1871C>T p.Ala624Val p.A624V ENST00000322893 NM_139318.4 624 gCc/gTc 0 +KCNH7 UCSF GRCh37 2 163291967 163291967 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 93 183 0 ENST00000332142.5:c.1695G>A p.Trp565Ter p.W565* ENST00000332142 NM_033272.3 565 tgG/tgA 0 +KCNJ12 UCSF GRCh37 17 21319253 21319253 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 31 108 0 ENST00000583088.1:c.599C>T p.Ala200Val p.A200V ENST00000583088 NM_021012.4 200 gCc/gTc 0 +KCNJ15 UCSF GRCh37 21 39671694 39671694 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 61 118 0 ENST00000328656.4:c.511C>T p.Pro171Ser p.P171S ENST00000328656 NM_002243.4 171 Ccc/Tcc 0 +KCNK16 UCSF GRCh37 6 39285631 39285631 + synonymous_variant Silent SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 22 28 59 0 ENST00000425054.2:c.426C>T p.His142= p.H142= ENST00000425054 NM_001135105.1 142 caC/caT 0 +KCNK16 UCSF GRCh37 6 39282934 39282934 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 47 89 0 ENST00000425054.2:c.935C>T p.Ala312Val p.A312V ENST00000425054 NM_001135105.1 312 gCt/gTt 0 +KCNN1 UCSF GRCh37 19 18084790 18084790 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 16 25 0 ENST00000222249.9:c.93C>T p.Gly31= p.G31= ENST00000222249 NM_002248.4 31 ggC/ggT 0 +KCNN3 UCSF GRCh37 1 154842381 154842381 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 12 24 0 ENST00000271915.4:c.60G>A p.Lys20= p.K20= ENST00000271915 NM_001204087.1 20 aaG/aaA 0 +KCNN4 UCSF GRCh37 19 44278504 44278504 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 10 20 0 ENST00000262888.3:c.523C>T p.Leu175Phe p.L175F ENST00000262888 NM_002250.2 175 Ctc/Ttc 0 +KCNQ1 UCSF GRCh37 11 2591913 2591913 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 0 27 53 0 ENST00000155840.5:c.533C>T p.Ala178Val p.A178V ENST00000155840 NM_000218.2 178 gCc/gTc 0 +KCNQ3 UCSF GRCh37 8 133182671 133182671 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 159 30 102 0 ENST00000388996.4:c.1145C>T p.Ala382Val p.A382V ENST00000388996 NM_004519.3 382 gCc/gTc 0 +KCNQ4 UCSF GRCh37 1 41298711 41298711 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 47 100 1 ENST00000347132.5:c.1539G>A p.Glu513= p.E513= ENST00000347132 NM_004700.3 513 gaG/gaA 0 +KCNS1 UCSF GRCh37 20 43726423 43726423 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 17 44 0 ENST00000306117.1:c.990C>T p.Gly330= p.G330= ENST00000306117 NM_002251.3 330 ggC/ggT 0 +KCNS3 UCSF GRCh37 2 18112819 18112819 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 58 142 0 ENST00000403915.1:c.544C>T p.Leu182= p.L182= ENST00000403915 NM_001282428.1 182 Ctg/Ttg 0 +KCNT1 UCSF GRCh37 9 138646990 138646990 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 15 38 0 ENST00000371757.2:c.515G>A p.Arg172Lys p.R172K ENST00000371757 NM_020822.2 172 aGa/aAa 0 +KCNV1 UCSF GRCh37 8 110980478 110980478 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 198 68 161 0 ENST00000524391.1:c.1342C>T p.Arg448Cys p.R448C ENST00000524391 448 Cgt/Tgt 0 +KCNV2 UCSF GRCh37 9 2717784 2717784 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 50 109 0 ENST00000382082.3:c.45C>T p.Pro15= p.P15= ENST00000382082 NM_133497.3 15 ccC/ccT 0 +KCTD9 UCSF GRCh37 8 25303750 25303750 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 86 157 1 ENST00000221200.4:c.65G>A p.Gly22Glu p.G22E ENST00000221200 NM_017634.3 22 gGa/gAa 0 +KDM5A UCSF GRCh37 12 430192 430192 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 106 204 0 ENST00000399788.2:c.2510C>T p.Pro837Leu p.P837L ENST00000399788 NM_001042603.1 837 cCg/cTg 0 +KDM5A UCSF GRCh37 12 443525 443525 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 130 89 233 0 ENST00000399788.2:c.1372C>T p.His458Tyr p.H458Y ENST00000399788 NM_001042603.1 458 Cat/Tat 0 +KDM5C UCSF GRCh37 X 53222334 53222334 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 25 45 0 ENST00000375401.3:c.4498G>A p.Glu1500Lys p.E1500K ENST00000375401 NM_004187.3 1500 Gag/Aag 0 +KIAA0100 UCSF GRCh37 17 26965374 26965374 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 61 123 0 ENST00000528896.2:c.1408C>T p.Leu470Phe p.L470F ENST00000528896 NM_014680.3 470 Ctc/Ttc 0 +KIAA0100 UCSF GRCh37 17 26948142 26948142 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 68 159 0 ENST00000528896.2:c.5106G>A p.Arg1702= p.R1702= ENST00000528896 NM_014680.3 1702 cgG/cgA 0 +KIAA0182 UCSF GRCh37 16 85687940 85687940 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 16 45 0 ENST00000253458.7:c.483G>A p.Pro161= p.P161= ENST00000253458 NM_014615.3 161 ccG/ccA 0 +KIAA0247 UCSF GRCh37 14 70175407 70175407 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 51 108 0 ENST00000342745.4:c.472G>A p.Val158Ile p.V158I ENST00000342745 NM_014734.3 158 Gta/Ata 0 +KIAA0415 UCSF GRCh37 7 4827833 4827833 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 8 13 0 ENST00000348624.4:c.1503G>A p.Arg501= p.R501= ENST00000348624 NM_014855.2 501 agG/agA 0 +KIAA0907 UCSF GRCh37 1 155884103 155884103 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 36 69 0 ENST00000368321.3:c.1654G>A p.Ala552Thr p.A552T ENST00000368321 NM_014949.2 552 Gcc/Acc 0 +KIAA0922 UCSF GRCh37 4 154512343 154512343 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 68 167 0 ENST00000409959.3:c.1809G>A p.Arg603= p.R603= ENST00000409959 NM_001131007.1 603 agG/agA 0 +KIAA0947 UCSF GRCh37 5 5443358 5443358 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 21 83 0 ENST00000296564.7:c.386+1G>A p.X129_splice ENST00000296564 NM_015325.2 0 +KIAA0947 UCSF GRCh37 5 5461667 5461667 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 142 128 226 0 ENST00000296564.7:c.2220G>A p.Arg740= p.R740= ENST00000296564 NM_015325.2 740 cgG/cgA 0 +KIAA1024 UCSF GRCh37 15 79750717 79750717 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 84 160 0 ENST00000305428.3:c.2228G>A p.Gly743Asp p.G743D ENST00000305428 NM_015206.2 743 gGc/gAc 0 +KIAA1107 UCSF GRCh37 1 92646067 92646067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 72 186 0 ENST00000370378.4:c.1513C>T p.Pro505Ser p.P505S ENST00000370378 NM_015237.2 505 Cct/Tct 0 +KIAA1161 UCSF GRCh37 9 34372612 34372612 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 16 25 0 ENST00000297625.7:c.228C>T p.Val76= p.V76= ENST00000297625 NM_020702.3 76 gtC/gtT 0 +KIAA1210 UCSF GRCh37 X 118220604 118220604 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 113 189 0 ENST00000402510.2:c.4589G>A p.Gly1530Glu p.G1530E ENST00000402510 NM_020721.1 1530 gGg/gAg 0 +KIAA1217 UCSF GRCh37 10 24508627 24508627 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 54 148 0 ENST00000376454.3:c.143C>T p.Ser48Phe p.S48F ENST00000376454 NM_019590.3 48 tCt/tTt 0 +KIAA1239 UCSF GRCh37 4 37445481 37445481 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 121 196 0 ENST00000309447.5:c.1871G>A p.Arg624Lys p.R624K ENST00000309447 NM_001144990.1 624 aGa/aAa 0 +KIAA1310 UCSF GRCh37 2 97279305 97279305 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 130 115 207 0 ENST00000431828.1:c.715G>A p.Ala239Thr p.A239T ENST00000431828 239 Gct/Act 0 +KIAA1462 UCSF GRCh37 10 30336638 30336638 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 144 68 112 0 ENST00000375377.1:c.104C>T p.Thr35Ile p.T35I ENST00000375377 NM_020848.2 35 aCt/aTt 0 +KIAA1522 UCSF GRCh37 1 33236702 33236702 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 52 86 0 ENST00000401073.2:c.1922C>T p.Ala641Val p.A641V ENST00000401073 NM_020888.2 641 gCc/gTc 0 +KIAA1524 UCSF GRCh37 3 108276236 108276236 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 63 91 0 ENST00000295746.8:c.2039G>A p.Arg680Lys p.R680K ENST00000295746 NM_020890.2 680 aGa/aAa 0 +KIAA1598 UCSF GRCh37 10 118666174 118666174 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 161 62 236 0 ENST00000355371.4:c.1444C>T p.Arg482Cys p.R482C ENST00000355371 NM_001258299.1 482 Cgt/Tgt 0 +KIAA1609 UCSF GRCh37 16 84520414 84520414 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 56 98 0 ENST00000343629.6:c.781G>A p.Glu261Lys p.E261K ENST00000343629 NM_020947.3 261 Gag/Aag 0 +KIAA1614 UCSF GRCh37 1 180885831 180885831 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 68 97 0 ENST00000367588.4:c.592G>A p.Asp198Asn p.D198N ENST00000367588 NM_020950.1 198 Gac/Aac 0 +KIAA1644 UCSF GRCh37 22 44692584 44692584 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 73 140 0 ENST00000381176.4:c.249C>T p.Asn83= p.N83= ENST00000381176 NM_001099294.1 83 aaC/aaT 0 +KIAA1683 UCSF GRCh37 19 18377737 18377737 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 32 58 0 ENST00000392413.4:c.613C>T p.Pro205Ser p.P205S ENST00000392413 NM_001145304.1 205 Ccc/Tcc 0 +KIAA1751 UCSF GRCh37 1 1918471 1918471 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 37 75 0 ENST00000270720.7:n.456G>A *152* ENST00000270720 0 +KIAA1755 UCSF GRCh37 20 36841641 36841641 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 27 57 0 ENST00000279024.4:c.3406G>A p.Ala1136Thr p.A1136T ENST00000279024 NM_001029864.1 1136 Gct/Act 0 +KIAA1755 UCSF GRCh37 20 36870139 36870139 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 74 154 0 ENST00000279024.4:c.394G>A p.Asp132Asn p.D132N ENST00000279024 NM_001029864.1 132 Gac/Aac 0 +KIAA1984 UCSF GRCh37 9 139693644 139693644 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 11 52 0 ENST00000338005.6:c.161G>A p.Arg54His p.R54H ENST00000338005 NM_001039374.4 54 cGc/cAc 0 +KIAA1984 UCSF GRCh37 9 139701056 139701056 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 66 75 0 ENST00000338005.6:c.1210C>T p.Leu404= p.L404= ENST00000338005 NM_001039374.4 404 Ctg/Ttg 0 +KIAA2022 UCSF GRCh37 X 73962350 73962350 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 46 114 0 ENST00000055682.6:c.2042G>A p.Gly681Asp p.G681D ENST00000055682 NM_001008537.2 681 gGt/gAt 0 +KIDINS220 UCSF GRCh37 2 8916981 8916981 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 70 136 0 ENST00000256707.3:c.2745C>T p.Arg915= p.R915= ENST00000256707 NM_020738.2 915 cgC/cgT 0 +KIF14 UCSF GRCh37 1 200587142 200587142 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 113 229 0 ENST00000367350.4:c.710C>T p.Thr237Met p.T237M ENST00000367350 NM_014875.2 237 aCg/aTg 0 +KIF14 UCSF GRCh37 1 200549469 200549469 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 50 130 0 ENST00000367350.4:c.3378G>A p.Arg1126= p.R1126= ENST00000367350 NM_014875.2 1126 cgG/cgA 0 +KIF14 UCSF GRCh37 1 200572392 200572392 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 75 182 0 ENST00000367350.4:c.1941G>A p.Arg647= p.R647= ENST00000367350 NM_014875.2 647 agG/agA 0 +KIF18B UCSF GRCh37 17 43012728 43012728 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 35 69 0 ENST00000593135.1:c.370G>A p.Gly124Arg p.G124R ENST00000593135 NM_001265577.1 124 Ggg/Agg 0 +KIF19 UCSF GRCh37 17 72350339 72350339 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 59 74 0 ENST00000389916.4:c.2347G>A p.Val783Met p.V783M ENST00000389916 NM_153209.3 783 Gtg/Atg 0 +KIF1B UCSF GRCh37 1 10384913 10384913 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 76 162 0 ENST00000263934.6:c.2497C>T p.Pro833Ser p.P833S ENST00000263934 NM_015074.3 833 Ccc/Tcc 0 +KIF1C UCSF GRCh37 17 4910581 4910581 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 22 32 0 ENST00000320785.5:c.1359G>A p.Glu453= p.E453= ENST00000320785 NM_006612.5 453 gaG/gaA 0 +KIF20B UCSF GRCh37 10 91477410 91477410 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 71 193 0 ENST00000260753.4:c.1202G>A p.Gly401Glu p.G401E ENST00000260753 NM_016195.2 401 gGg/gAg 0 +KIF25 UCSF GRCh37 6 168445564 168445564 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 53 122 0 ENST00000443060.2:c.1043C>T p.Ala348Val p.A348V ENST00000443060 348 gCa/gTa 0 +KIF26B UCSF GRCh37 1 245850229 245850229 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 55 85 0 ENST00000407071.2:c.3944C>T p.Ala1315Val p.A1315V ENST00000407071 NM_018012.3 1315 gCc/gTc 0 +KIF27 UCSF GRCh37 9 86495271 86495271 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 358 125 352 0 ENST00000297814.2:c.2584G>A p.Glu862Lys p.E862K ENST00000297814 NM_017576.2 862 Gaa/Aaa 0 +KIF4B UCSF GRCh37 5 154393942 154393942 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 128 102 252 0 ENST00000435029.4:c.523G>A p.Gly175Arg p.G175R ENST00000435029 NM_001099293.1 175 Gga/Aga 0 +KIF4B UCSF GRCh37 5 154396999 154396999 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 52 142 0 ENST00000435029.4:c.3580G>A p.Glu1194Lys p.E1194K ENST00000435029 NM_001099293.1 1194 Gag/Aag 0 +KIF6 UCSF GRCh37 6 39507857 39507857 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 140 105 193 0 ENST00000287152.7:c.1567C>T p.Arg523Ter p.R523* ENST00000287152 NM_145027.4 523 Cga/Tga 0 +KIF7 UCSF GRCh37 15 90188645 90188645 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 39 54 0 ENST00000394412.3:c.1960C>T p.Arg654Cys p.R654C ENST00000394412 NM_198525.2 654 Cgc/Tgc 0 +KIRREL3 UCSF GRCh37 11 126870381 126870381 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 11 36 0 ENST00000525144.2:c.25C>T p.Leu9Phe p.L9F ENST00000525144 NM_032531.3 9 Ctc/Ttc 0 +KIRREL3 UCSF GRCh37 11 126294874 126294874 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 38 0 ENST00000525144.2:c.1938C>T p.His646= p.H646= ENST00000525144 NM_032531.3 646 caC/caT 0 +KL UCSF GRCh37 13 33591182 33591182 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 15 16 0 ENST00000380099.3:c.604G>A p.Asp202Asn p.D202N ENST00000380099 NM_004795.3 202 Gac/Aac 0 +KL UCSF GRCh37 13 33635449 33635449 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 54 171 0 ENST00000380099.3:c.2233G>A p.Asp745Asn p.D745N ENST00000380099 NM_004795.3 745 Gac/Aac 0 +KLB UCSF GRCh37 4 39450107 39450107 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 72 164 0 ENST00000257408.4:c.2936C>T p.Thr979Ile p.T979I ENST00000257408 NM_175737.3 979 aCc/aTc 0 +KLB UCSF GRCh37 4 39436095 39436095 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 97 172 0 ENST00000257408.4:c.1091G>A p.Arg364Lys p.R364K ENST00000257408 NM_175737.3 364 aGa/aAa 0 +KLC1 UCSF GRCh37 14 104129146 104129146 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 49 75 0 ENST00000452929.2:c.679G>A p.Gly227Arg p.G227R ENST00000452929 NM_001130107.1 227 Ggg/Agg 0 +KLC2 UCSF GRCh37 11 66026132 66026132 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 22 86 0 ENST00000417856.1:c.67G>A p.Ala23Thr p.A23T ENST00000417856 NM_001134775.1 23 Gct/Act 0 +KLF15 UCSF GRCh37 3 126071339 126071339 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 36 71 0 ENST00000296233.3:c.427G>A p.Glu143Lys p.E143K ENST00000296233 NM_014079.3 143 Gag/Aag 0 +KLHL1 UCSF GRCh37 13 70549775 70549775 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 76 194 0 ENST00000377844.4:c.657G>A p.Gly219= p.G219= ENST00000377844 NM_020866.2 219 ggG/ggA 0 +KLHL11 UCSF GRCh37 17 40010205 40010205 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 113 161 0 ENST00000319121.3:c.1914G>A p.Arg638= p.R638= ENST00000319121 NM_018143.1 638 agG/agA 0 +KLHL13 UCSF GRCh37 X 117044028 117044028 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 64 143 0 ENST00000539496.1:c.611G>A p.Arg204Gln p.R204Q ENST00000539496 NM_001168299.1 204 cGg/cAg 0 +KLHL21 UCSF GRCh37 1 6659327 6659327 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 28 56 0 ENST00000377658.4:c.1207G>A p.Glu403Lys p.E403K ENST00000377658 NM_014851.2 403 Gag/Aag 0 +KLHL3 UCSF GRCh37 5 136974757 136974757 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 25 62 0 ENST00000309755.4:c.1104C>T p.Asp368= p.D368= ENST00000309755 NM_017415.2 368 gaC/gaT 0 +KLHL30 UCSF GRCh37 2 239056482 239056482 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 18 43 0 ENST00000409223.1:c.1158C>T p.Thr386= p.T386= ENST00000409223 386 acC/acT 0 +KLHL33 UCSF GRCh37 14 20897381 20897381 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 21 51 0 ENST00000344581.4:c.1229G>A p.Gly410Asp p.G410D ENST00000344581 NM_001109997.2 410 gGc/gAc 0 +KLHL8 UCSF GRCh37 4 88106778 88106778 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 74 153 0 ENST00000273963.5:c.390C>T p.Leu130= p.L130= ENST00000273963 NM_020803.3 130 ctC/ctT 0 +KLK13 UCSF GRCh37 19 51563773 51563773 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 39 113 0 ENST00000595793.1:c.156C>T p.Ala52= p.A52= ENST00000595793 NM_015596.1 52 gcC/gcT 0 +KLK4 UCSF GRCh37 19 51411834 51411834 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 57 129 0 ENST00000324041.1:c.475+1G>A p.X159_splice ENST00000324041 NM_004917.3 0 +KLK8 UCSF GRCh37 19 51501085 51501085 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 51 142 1 ENST00000391806.2:c.684G>A p.Lys228= p.K228= ENST00000391806 228 aaG/aaA 0 +KLRG2 UCSF GRCh37 7 139168313 139168313 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 10 25 0 ENST00000340940.4:c.76G>A p.Val26Ile p.V26I ENST00000340940 NM_198508.2 26 Gtc/Atc 0 +KNTC1 UCSF GRCh37 12 123065191 123065191 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 62 144 0 ENST00000333479.7:c.2956C>T p.Leu986= p.L986= ENST00000333479 NM_014708.4 986 Cta/Tta 0 +KNTC1 UCSF GRCh37 12 123105155 123105155 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 129 84 196 0 ENST00000333479.7:c.6279G>A p.Lys2093= p.K2093= ENST00000333479 NM_014708.4 2093 aaG/aaA 0 +KPRP UCSF GRCh37 1 152733324 152733324 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 87 146 0 ENST00000368773.1:c.1260G>A p.Pro420= p.P420= ENST00000368773 NM_001025231.1 420 ccG/ccA 0 +KPTN UCSF GRCh37 19 47979872 47979872 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 12 43 0 ENST00000338134.3:c.1099C>T p.Leu367= p.L367= ENST00000338134 NM_007059.2 367 Ctg/Ttg 0 +KREMEN2 UCSF GRCh37 16 3014543 3014543 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 17 49 0 ENST00000303746.5:c.22G>A p.Gly8Ser p.G8S ENST00000303746 8 Ggc/Agc 0 +KRT16 UCSF GRCh37 17 39766220 39766220 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 14 26 0 ENST00000301653.4:c.1389C>T p.Ser463= p.S463= ENST00000301653 NM_005557.3 463 agC/agT 0 +KRT17 UCSF GRCh37 17 39777062 39777062 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 82 148 0 ENST00000311208.8:c.1030G>A p.Gly344Arg p.G344R ENST00000311208 NM_000422.2 344 Ggg/Agg 0 +KRT23 UCSF GRCh37 17 39092689 39092689 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 62 130 0 ENST00000209718.3:c.167G>A p.Gly56Glu p.G56E ENST00000209718 NM_015515.3 56 gGa/gAa 0 +KRT38 UCSF GRCh37 17 39596466 39596466 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 46 123 0 ENST00000246646.3:c.522G>A p.Arg174= p.R174= ENST00000246646 NM_006771.3 174 agG/agA 0 +KRT5 UCSF GRCh37 12 52913654 52913654 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 87 143 0 ENST00000252242.4:c.427G>A p.Val143Ile p.V143I ENST00000252242 NM_000424.3 143 Gtc/Atc 0 +KRT78 UCSF GRCh37 12 53233613 53233613 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 70 90 0 ENST00000304620.4:c.1203C>T p.Ser401= p.S401= ENST00000304620 NM_173352.2 401 agC/agT 0 +KRT8 UCSF GRCh37 12 53292248 53292248 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 17 62 0 ENST00000552150.1:c.1342G>A p.Ala448Thr p.A448T ENST00000552150 NM_001256282.1 448 Gca/Aca 0 +KRTAP4-9 UCSF GRCh37 17 39261982 39261982 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 54 81 0 ENST00000391415.1:c.342C>T p.Cys114= p.C114= ENST00000391415 NM_001146041.1 114 tgC/tgT 0 +KRTAP6-3 UCSF GRCh37 21 31964836 31964836 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 80 176 1 ENST00000391624.1:c.51C>T p.Cys17= p.C17= ENST00000391624 NM_181605.3 17 tgC/tgT 0 +KSR2 UCSF GRCh37 12 118198996 118198996 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 46 72 0 ENST00000339824.5:c.806C>T p.Thr269Ile p.T269I ENST00000339824 269 aCc/aTc 0 +LAD1 UCSF GRCh37 1 201355974 201355974 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 101 164 0 ENST00000391967.2:c.515G>A p.Gly172Glu p.G172E ENST00000391967 NM_005558.3 172 gGg/gAg 0 +LAMA2 UCSF GRCh37 6 129687384 129687384 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P10_Rec Untested WXS Illumina HiSeq 41 0 ENST00000421865.2:c.4739del p.Gly1580AlafsTer15 p.G1580Afs*15 ENST00000421865 NM_001079823.1 1580 Ggc/gc 0 +LAMA2 UCSF GRCh37 6 129714201 129714201 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 63 170 0 ENST00000421865.2:c.5246C>T p.Ala1749Val p.A1749V ENST00000421865 NM_001079823.1 1749 gCc/gTc 0 +LAMA3 UCSF GRCh37 18 21395538 21395538 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 41 120 0 ENST00000313654.9:c.2047+1G>A p.X683_splice ENST00000313654 NM_198129.1 0 +LAMA4 UCSF GRCh37 6 112499418 112499418 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 65 101 0 ENST00000230538.7:c.1094G>A p.Arg365Lys p.R365K ENST00000230538 NM_001105206.2 365 aGa/aAa 0 +LAMA4 UCSF GRCh37 6 112460974 112460974 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 76 169 0 ENST00000230538.7:c.3090C>T p.Ser1030= p.S1030= ENST00000230538 NM_001105206.2 1030 tcC/tcT 0 +LAMA5 UCSF GRCh37 20 60889928 60889928 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 48 66 0 ENST00000252999.3:c.8123C>T p.Ala2708Val p.A2708V ENST00000252999 NM_005560.4 2708 gCc/gTc 0 +LAMB1 UCSF GRCh37 7 107594095 107594095 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 75 146 0 ENST00000222399.6:c.2959C>T p.Pro987Ser p.P987S ENST00000222399 NM_002291.2 987 Cca/Tca 0 +LAMB1 UCSF GRCh37 7 107575896 107575896 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 95 204 0 ENST00000222399.6:c.4152G>A p.Lys1384= p.K1384= ENST00000222399 NM_002291.2 1384 aaG/aaA 0 +LAMB3 UCSF GRCh37 1 209800835 209800835 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 31 63 0 ENST00000391911.1:c.1378C>T p.Pro460Ser p.P460S ENST00000391911 NM_001017402.1 460 Ccc/Tcc 0 +LAMC2 UCSF GRCh37 1 183197740 183197740 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 68 129 0 ENST00000264144.4:c.1700C>T p.Ala567Val p.A567V ENST00000264144 NM_005562.2 567 gCa/gTa 0 +LAMC3 UCSF GRCh37 9 133932472 133932472 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.010,1000g2011may_all_0.0351,snp132_rs61737720 P10_Rec Untested WXS Illumina HiSeq 120 61 111 0 ENST00000361069.4:c.2096G>A p.Gly699Asp p.G699D ENST00000361069 NM_006059.3 699 gGt/gAt 0 +LAP3 UCSF GRCh37 4 17608484 17608484 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 58 156 0 ENST00000226299.4:c.1293G>A p.Arg431= p.R431= ENST00000226299 NM_015907.2 431 agG/agA 0 +LARS UCSF GRCh37 5 145508612 145508612 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 39 36 104 0 ENST00000394434.2:c.2698C>T p.Gln900Ter p.Q900* ENST00000394434 NM_020117.9 900 Cag/Tag 0 +LAS1L UCSF GRCh37 X 64748194 64748194 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 6 26 0 ENST00000374811.3:c.902C>T p.Ser301Phe p.S301F ENST00000374811 NM_031206.4 301 tCc/tTc 0 +LATS1 UCSF GRCh37 6 149997779 149997779 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 42 71 0 ENST00000253339.5:c.2688G>A p.Arg896= p.R896= ENST00000253339 896 cgG/cgA 0 +LAX1 UCSF GRCh37 1 203743526 203743526 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 85 140 0 ENST00000442561.2:c.914G>A p.Ser305Asn p.S305N ENST00000442561 NM_017773.3 305 aGc/aAc 0 +LCE3E UCSF GRCh37 1 152538436 152538436 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 95 161 0 ENST00000368789.1:c.249C>T p.Gly83= p.G83= ENST00000368789 NM_178435.3 83 ggC/ggT 0 +LCK UCSF GRCh37 1 32740015 32740015 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 65 108 0 ENST00000336890.5:c.85C>T p.Pro29Ser p.P29S ENST00000336890 NM_005356.3 29 Cca/Tca 0 +LCT UCSF GRCh37 2 136561679 136561679 + missense_variant Missense_Mutation SNP T T A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 41 120 0 ENST00000264162.2:c.4484A>T p.Asp1495Val p.D1495V ENST00000264162 NM_002299.2 1495 gAc/gTc 0 +LDB2 UCSF GRCh37 4 16504426 16504426 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 117 104 198 0 ENST00000304523.5:c.962C>T p.Thr321Ile p.T321I ENST00000304523 NM_001290.3 321 aCt/aTt 0 +LDB2 UCSF GRCh37 4 16504319 16504319 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 110 192 0 ENST00000304523.5:c.1069C>T p.Pro357Ser p.P357S ENST00000304523 NM_001290.3 357 Ccc/Tcc 0 +LDB3 UCSF GRCh37 10 88441418 88441418 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 43 79 0 ENST00000429277.2:c.547C>T p.Pro183Ser p.P183S ENST00000429277 NM_001171610.1 183 Cca/Tca 0 +LEAP2 UCSF GRCh37 5 132209757 132209757 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 52 131 0 ENST00000296877.2:c.173C>T p.Ser58Phe p.S58F ENST00000296877 NM_052971.2 58 tCt/tTt 0 +LEPREL1 UCSF GRCh37 3 189706695 189706695 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 78 183 0 ENST00000319332.5:c.955+1G>A p.X319_splice ENST00000319332 NM_018192.3 0 +LGALS9B UCSF GRCh37 17 20361598 20361598 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 48 243 0 ENST00000324290.5:c.231G>A p.Arg77= p.R77= ENST00000324290 NM_001042685.1 77 agG/agA 0 +LGR5 UCSF GRCh37 12 71834027 71834027 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 42 47 0 ENST00000266674.5:c.167G>A p.Gly56Glu p.G56E ENST00000266674 NM_001277226.1 56 gGg/gAg 0 +LHFPL2 UCSF GRCh37 5 77805969 77805969 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 54 113 0 ENST00000380345.2:c.68C>T p.Ala23Val p.A23V ENST00000380345 NM_005779.2 23 gCc/gTc 0 +LHX2 UCSF GRCh37 9 126777518 126777518 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 79 141 0 ENST00000373615.4:c.441C>T p.Asn147= p.N147= ENST00000373615 NM_004789.3 147 aaC/aaT 0 +LHX4 UCSF GRCh37 1 180243477 180243477 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 96 190 0 ENST00000263726.2:c.936G>A p.Gln312= p.Q312= ENST00000263726 NM_033343.3 312 caG/caA 0 +LILRB3 UCSF GRCh37 19 54725769 54725769 + missense_variant Missense_Mutation SNP A A T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 31 109 0 ENST00000245620.9:c.589T>A p.Tyr197Asn p.Y197N ENST00000245620 197 Tat/Aat 0 +LIMA1 UCSF GRCh37 12 50615987 50615987 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 106 192 0 ENST00000394943.3:c.447G>A p.Glu149= p.E149= ENST00000394943 149 gaG/gaA 0 +LLGL1 UCSF GRCh37 17 18137478 18137478 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 24 29 0 ENST00000316843.4:c.703C>T p.Leu235= p.L235= ENST00000316843 NM_004140.3 235 Ctg/Ttg 0 +LMBRD1 UCSF GRCh37 6 70411348 70411348 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 17 63 0 ENST00000370577.3:c.1070C>T p.Pro357Leu p.P357L ENST00000370577 NM_018368.3 357 cCt/cTt 0 +LNP1 UCSF GRCh37 3 100148694 100148694 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 56 119 0 ENST00000383693.3:c.121G>A p.Ala41Thr p.A41T ENST00000383693 NM_001085451.1 41 Gcc/Acc 0 +LOC100129924 UCSF GRCh37 1 43255568 43255568 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 59 110 0 ENST00000421630.1:c.89G>A p.Val31Met p.V31M ENST00000421630 NM_001242750.1 31 Gtg/Atg 0 +LOC120824 UCSF GRCh37 11 49002870 49002870 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 112 214 0 ENST00000534741.1:n.378C>T *126* ENST00000534741 0 +LOC388946 UCSF GRCh37 2 46711561 46711561 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 121 112 231 0 ENST00000434431.1:c.656C>T p.Ser219Leu p.S219L ENST00000434431 NM_001145051.2 219 tCa/tTa 0 +LOH12CR1 UCSF GRCh37 12 12510410 12510410 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 15 30 0 ENST00000314565.4:c.25G>A p.Ala9Thr p.A9T ENST00000314565 NM_058169.3 9 Gcc/Acc 0 +LONP2 UCSF GRCh37 16 48278417 48278417 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 9 20 0 ENST00000285737.4:c.118C>T p.Gln40Ter p.Q40* ENST00000285737 NM_031490.2 40 Cag/Tag 0 +LOX UCSF GRCh37 5 121413366 121413366 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 10 11 0 ENST00000231004.4:c.315G>A p.Arg105= p.R105= ENST00000231004 NM_002317.5 105 cgG/cgA 0 +LOXHD1 UCSF GRCh37 18 44159706 44159706 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 37 83 0 ENST00000398722.4:c.862G>A p.Gly288Ser p.G288S ENST00000398722 288 Ggt/Agt 0 +LOXHD1 UCSF GRCh37 18 44122802 44122802 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 29 112 0 ENST00000300591.6:c.303G>A p.Lys101= p.K101= ENST00000300591 NM_001145472.2 101 aaG/aaA 0 +LOXHD1 UCSF GRCh37 18 44104875 44104875 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 4 30 0 ENST00000300591.6:c.1203C>T p.Asp401= p.D401= ENST00000300591 NM_001145472.2 401 gaC/gaT 0 +LPXN UCSF GRCh37 11 58318693 58318693 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 40 85 0 ENST00000528954.1:c.346G>A p.Ala116Thr p.A116T ENST00000528954 NM_001143995.1 116 Gca/Aca 0 +LRBA UCSF GRCh37 4 151408963 151408963 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001 P10_Rec Untested WXS Illumina HiSeq 63 49 123 0 ENST00000357115.3:c.6505G>A p.Asp2169Asn p.D2169N ENST00000357115 NM_006726.4 2169 Gac/Aac 0 +LRBA UCSF GRCh37 4 151203777 151203777 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 53 110 0 ENST00000357115.3:c.8174C>T p.Ser2725Phe p.S2725F ENST00000357115 NM_006726.4 2725 tCc/tTc 0 +LRCH4 UCSF GRCh37 7 100173932 100173932 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 21 39 0 ENST00000310300.6:c.1567G>A p.Asp523Asn p.D523N ENST00000310300 NM_002319.3 523 Gac/Aac 0 +LRFN3 UCSF GRCh37 19 36430445 36430445 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 15 33 0 ENST00000588831.1:c.118C>T p.Pro40Ser p.P40S ENST00000588831 40 Ccc/Tcc 0 +LRG1 UCSF GRCh37 19 4538787 4538787 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 42 72 0 ENST00000306390.6:c.209C>T p.Thr70Ile p.T70I ENST00000306390 NM_052972.2 70 aCc/aTc 0 +LRP1B UCSF GRCh37 2 141259338 141259338 + missense_variant Missense_Mutation SNP C C T snp132_rs77813209 P10_Rec Untested WXS Illumina HiSeq 77 74 178 0 ENST00000389484.3:c.8768G>A p.Arg2923Lys p.R2923K ENST00000389484 NM_018557.2 2923 aGa/aAa 0 +LRP2 UCSF GRCh37 2 170101379 170101379 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 72 198 0 ENST00000263816.3:c.3254G>A p.Arg1085His p.R1085H ENST00000263816 NM_004525.2 1085 cGc/cAc 0 +LRRC24 UCSF GRCh37 8 145748767 145748767 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 20 35 0 ENST00000529415.2:c.634C>T p.Leu212= p.L212= ENST00000529415 212 Ctg/Ttg 0 +LRRC45 UCSF GRCh37 17 79983276 79983276 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 39 126 0 ENST00000306688.3:c.554G>A p.Gly185Asp p.G185D ENST00000306688 NM_144999.2 185 gGc/gAc 0 +LRRC48 UCSF GRCh37 17 17910712 17910712 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 70 152 0 ENST00000313838.8:c.1326+251G>A *442* ENST00000313838 NM_001130090.1 0 +LRRC49 UCSF GRCh37 15 71188259 71188259 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 27 111 0 ENST00000560369.1:c.192C>T p.Asn64= p.N64= ENST00000560369 64 aaC/aaT 0 +LRRC4C UCSF GRCh37 11 40137279 40137279 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 101 206 0 ENST00000278198.2:c.564C>T p.Ile188= p.I188= ENST00000278198 188 atC/atT 0 +LRRC4C UCSF GRCh37 11 40137585 40137585 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 5 63 133 0 ENST00000278198.2:c.258C>T p.Asn86= p.N86= ENST00000278198 86 aaC/aaT 0 +LRRIQ1 UCSF GRCh37 12 85546078 85546078 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 65 159 0 ENST00000393217.2:c.4350G>A p.Trp1450Ter p.W1450* ENST00000393217 NM_001079910.1 1450 tgG/tgA 0 +LRRIQ4 UCSF GRCh37 3 169540582 169540582 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 73 163 0 ENST00000340806.6:c.873C>T p.Gly291= p.G291= ENST00000340806 NM_001080460.1 291 ggC/ggT 0 +LRRK2 UCSF GRCh37 12 40696608 40696608 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 77 194 0 ENST00000298910.7:c.3514C>T p.Pro1172Ser p.P1172S ENST00000298910 NM_198578.3 1172 Cct/Tct 0 +LRRTM1 UCSF GRCh37 2 80530170 80530170 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 52 111 0 ENST00000295057.3:c.775G>A p.Glu259Lys p.E259K ENST00000295057 NM_178839.4 259 Gag/Aag 0 +LRRTM3 UCSF GRCh37 10 68687617 68687617 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 83 181 0 ENST00000361320.4:c.943G>A p.Glu315Lys p.E315K ENST00000361320 NM_178011.3 315 Gaa/Aaa 0 +LRRTM3 UCSF GRCh37 10 68687235 68687235 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 96 203 0 ENST00000361320.4:c.561C>T p.Asp187= p.D187= ENST00000361320 NM_178011.3 187 gaC/gaT 0 +LRWD1 UCSF GRCh37 7 102108556 102108556 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 14 20 0 ENST00000292616.5:c.726C>T p.Leu242= p.L242= ENST00000292616 NM_152892.1 242 ctC/ctT 0 +LSG1 UCSF GRCh37 3 194387006 194387006 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 65 150 0 ENST00000265245.5:c.360C>T p.Asn120= p.N120= ENST00000265245 NM_018385.2 120 aaC/aaT 0 +LSMD1 UCSF GRCh37 17 7760127 7760127 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 49 100 0 ENST00000333775.5:c.444C>T p.Gly148= p.G148= ENST00000333775 NM_032356.3 148 ggC/ggT 0 +LTBP1 UCSF GRCh37 2 33623550 33623550 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 58 130 0 ENST00000404816.2:c.5104C>T p.Pro1702Ser p.P1702S ENST00000404816 1702 Cca/Tca 0 +LTK UCSF GRCh37 15 41804429 41804429 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 16 43 0 ENST00000263800.6:c.394G>A p.Ala132Thr p.A132T ENST00000263800 NM_002344.5 132 Gcc/Acc 0 +LTN1 UCSF GRCh37 21 30304865 30304865 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 132 131 227 0 ENST00000389194.2:c.5135G>A p.Gly1712Glu p.G1712E ENST00000389194 NM_015565.2 1712 gGg/gAg 0 +LTN1 UCSF GRCh37 21 30313628 30313628 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 67 184 0 ENST00000389194.2:c.4534C>T p.Pro1512Ser p.P1512S ENST00000389194 NM_015565.2 1512 Cca/Tca 0 +LTN1 UCSF GRCh37 21 30316208 30316208 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 70 173 0 ENST00000389194.2:c.4139C>T p.Ser1380Phe p.S1380F ENST00000389194 NM_015565.2 1380 tCt/tTt 0 +LUZP1 UCSF GRCh37 1 23420637 23420637 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 76 213 0 ENST00000302291.4:c.118G>A p.Ala40Thr p.A40T ENST00000302291 40 Gca/Aca 0 +LY75 UCSF GRCh37 2 160750565 160750565 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 57 186 0 ENST00000504764.1:c.497G>A p.Gly166Glu p.G166E ENST00000504764 NM_001198759.1 166 gGg/gAg 0 +LYPD4 UCSF GRCh37 19 42342085 42342085 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 53 121 0 ENST00000330743.3:c.462C>T p.Leu154= p.L154= ENST00000330743 NM_173506.4 154 ctC/ctT 0 +MACF1 UCSF GRCh37 1 39759204 39759204 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 87 211 0 ENST00000545844.1:c.2082C>T p.Ile694= p.I694= ENST00000545844 694 atC/atT 0 +MACF1 UCSF GRCh37 1 39913788 39913788 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 66 152 0 ENST00000545844.1:c.13875C>T p.Asp4625= p.D4625= ENST00000545844 4625 gaC/gaT 0 +MACROD1 UCSF GRCh37 11 63766310 63766310 + splice_region_variant,3_prime_UTR_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 4 21 0 ENST00000255681.6:c.*30G>A p.X10_splice ENST00000255681 NM_014067.3 0 +MAD2L2 UCSF GRCh37 1 11736191 11736191 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 27 58 0 ENST00000235310.3:c.339C>T p.Asp113= p.D113= ENST00000235310 113 gaC/gaT 0 +MAG UCSF GRCh37 19 35793430 35793430 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 41 109 0 ENST00000392213.3:c.1050G>A p.Gln350= p.Q350= ENST00000392213 NM_002361.3 350 caG/caA 0 +MAGEB3 UCSF GRCh37 X 30254867 30254867 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 75 158 0 ENST00000361644.2:c.826G>A p.Gly276Ser p.G276S ENST00000361644 NM_002365.4 276 Ggt/Agt 0 +MAGEB6 UCSF GRCh37 X 26212424 26212424 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 76 211 0 ENST00000379034.1:c.461C>T p.Thr154Ile p.T154I ENST00000379034 NM_173523.2 154 aCt/aTt 0 +MAGED2 UCSF GRCh37 X 54841848 54841848 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 40 41 90 0 ENST00000375068.1:c.1554G>A p.Trp518Ter p.W518* ENST00000375068 518 tgG/tgA 0 +MAGED2 UCSF GRCh37 X 54838651 54838651 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 44 96 0 ENST00000375068.1:c.1052C>T p.Thr351Ile p.T351I ENST00000375068 351 aCc/aTc 0 +MAGI2 UCSF GRCh37 7 77649240 77649240 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 20 39 50 0 ENST00000354212.4:c.3760G>A p.Val1254Ile p.V1254I ENST00000354212 NM_012301.3 1254 Gta/Ata 0 +MAGI3 UCSF GRCh37 1 113933844 113933844 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 7 15 0 ENST00000307546.9:c.189G>A p.Lys63= p.K63= ENST00000307546 NM_001142782.1 63 aaG/aaA 0 +MAK UCSF GRCh37 6 10791958 10791958 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 64 179 0 ENST00000313243.2:c.1266G>A p.Lys422= p.K422= ENST00000313243 422 aaG/aaA 0 +MAK16 UCSF GRCh37 8 33346598 33346598 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 67 201 0 ENST00000360128.6:c.333G>A p.Gln111= p.Q111= ENST00000360128 NM_032509.3 111 caG/caA 0 +MAL2 UCSF GRCh37 8 120252459 120252459 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 348 107 164 0 ENST00000276681.6:c.358G>A p.Glu120Lys p.E120K ENST00000276681 NM_052886.2 120 Gaa/Aaa 0 +MAMDC4 UCSF GRCh37 9 139748472 139748472 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 135 47 123 0 ENST00000317446.2:c.614C>T p.Thr205Ile p.T205I ENST00000317446 NM_206920.2 205 aCc/aTc 0 +MAMDC4 UCSF GRCh37 9 139750500 139750500 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 42 96 0 ENST00000317446.2:c.1619G>A p.Gly540Glu p.G540E ENST00000317446 NM_206920.2 540 gGg/gAg 0 +MAML3 UCSF GRCh37 4 141074079 141074079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 7 23 0 ENST00000509479.2:c.403C>T p.Pro135Ser p.P135S ENST00000509479 NM_018717.4 135 Ccg/Tcg 0 +MAMSTR UCSF GRCh37 19 49218605 49218605 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 22 52 0 ENST00000318083.6:c.339G>A p.Arg113= p.R113= ENST00000318083 113 agG/agA 0 +MAN2B1 UCSF GRCh37 19 12759216 12759216 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 21 52 0 ENST00000456935.2:c.2437G>A p.Val813Met p.V813M ENST00000456935 NM_000528.3 813 Gtg/Atg 0 +MANF UCSF GRCh37 3 51425239 51425239 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 94 193 0 ENST00000528157.1:c.294C>T p.His98= p.H98= ENST00000528157 NM_006010.4 98 caC/caT 0 +MAP1A UCSF GRCh37 15 43819862 43819862 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.0018 P10_Rec Untested WXS Illumina HiSeq 35 49 72 0 ENST00000300231.5:c.6191C>T p.Pro2064Leu p.P2064L ENST00000300231 2064 cCc/cTc 0 +MAP1B UCSF GRCh37 5 71403432 71403432 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 11 16 0 ENST00000296755.7:c.74C>T p.Ser25Leu p.S25L ENST00000296755 NM_005909.3 25 tCg/tTg 0 +MAP1S UCSF GRCh37 19 17838521 17838521 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 19 41 0 ENST00000324096.4:c.2328G>A p.Gly776= p.G776= ENST00000324096 NM_018174.4 776 ggG/ggA 0 +MAP2 UCSF GRCh37 2 210560323 210560323 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 84 151 0 ENST00000360351.4:c.3429G>A p.Glu1143= p.E1143= ENST00000360351 NM_002374.3 1143 gaG/gaA 0 +MAP3K14 UCSF GRCh37 17 43345108 43345108 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 72 179 0 ENST00000344686.2:n.2097C>T *699* ENST00000344686 0 +MAP3K4 UCSF GRCh37 6 161470113 161470113 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 53 132 0 ENST00000392142.4:c.809C>T p.Ala270Val p.A270V ENST00000392142 NM_005922.2 270 gCc/gTc 0 +MAP3K4 UCSF GRCh37 6 161519420 161519420 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 76 177 0 ENST00000392142.4:c.3635C>T p.Ser1212Phe p.S1212F ENST00000392142 NM_005922.2 1212 tCt/tTt 0 +MAP3K9 UCSF GRCh37 14 71199907 71199907 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 50 93 0 ENST00000555993.2:c.2221G>A p.Ala741Thr p.A741T ENST00000555993 NM_033141.2 741 Gcc/Acc 0 +MAP3K9 UCSF GRCh37 14 71215576 71215576 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 62 149 0 ENST00000555993.2:c.1296G>A p.Glu432= p.E432= ENST00000555993 NM_033141.2 432 gaG/gaA 0 +MAP4K4 UCSF GRCh37 2 102477371 102477371 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 67 149 0 ENST00000347699.4:c.1789C>T p.Pro597Ser p.P597S ENST00000347699 NM_145687.3 597 Cct/Tct 0 +MAP7D2 UCSF GRCh37 X 20044013 20044013 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 115 222 0 ENST00000379643.5:c.1065G>A p.Gly355= p.G355= ENST00000379643 NM_001168465.1 355 ggG/ggA 0 +MAPK7 UCSF GRCh37 17 19286515 19286515 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 41 64 0 ENST00000308406.5:c.2422G>A p.Ala808Thr p.A808T ENST00000308406 NM_139033.2 808 Gct/Act 0 +MAPK8IP3 UCSF GRCh37 16 1756385 1756385 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 16 16 0 ENST00000250894.4:c.45C>T p.Tyr15= p.Y15= ENST00000250894 NM_015133.3 15 taC/taT 0 +MARVELD3 UCSF GRCh37 16 71668385 71668385 + intron_variant Intron SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 67 102 0 ENST00000299952.4:c.595+4988C>T *199* ENST00000299952 NM_001017967.3 0 +MASP1 UCSF GRCh37 3 186961389 186961389 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 83 186 0 ENST00000296280.6:c.1111G>A p.Gly371Arg p.G371R ENST00000296280 NM_139125.3 371 Gga/Aga 0 +MASP2 UCSF GRCh37 1 11094897 11094897 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 18 41 0 ENST00000400897.3:c.1075C>T p.Pro359Ser p.P359S ENST00000400897 NM_006610.3 359 Ccc/Tcc 0 +MAST1 UCSF GRCh37 19 12980027 12980027 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 63 128 0 ENST00000251472.4:c.2921G>A p.Gly974Asp p.G974D ENST00000251472 NM_014975.2 974 gGc/gAc 0 +MAST1 UCSF GRCh37 19 12981740 12981740 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 99 172 0 ENST00000251472.4:c.3106G>A p.Val1036Ile p.V1036I ENST00000251472 NM_014975.2 1036 Gtc/Atc 0 +MAST2 UCSF GRCh37 1 46295118 46295118 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 77 118 0 ENST00000361297.2:c.333G>A p.Gln111= p.Q111= ENST00000361297 NM_015112.2 111 caG/caA 0 +MAST3 UCSF GRCh37 19 18241465 18241465 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 57 136 0 ENST00000262811.6:c.1298C>T p.Ser433Phe p.S433F ENST00000262811 NM_015016.1 433 tCc/tTc 0 +MAST3 UCSF GRCh37 19 18235099 18235099 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 57 80 0 ENST00000262811.6:c.781G>A p.Glu261Lys p.E261K ENST00000262811 NM_015016.1 261 Gag/Aag 0 +MATN4 UCSF GRCh37 20 43927138 43927138 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 54 113 0 ENST00000537548.1:c.1098C>T p.Arg366= p.R366= ENST00000537548 NM_003833.4 366 cgC/cgT 0 +MC2R UCSF GRCh37 18 13884907 13884907 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 64 106 0 ENST00000327606.3:c.611C>T p.Thr204Ile p.T204I ENST00000327606 NM_000529.2 204 aCc/aTc 0 +MCCC2 UCSF GRCh37 5 70945927 70945927 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 103 214 1 ENST00000340941.6:c.1405C>T p.Arg469Cys p.R469C ENST00000340941 NM_022132.4 469 Cgt/Tgt 0 +MCF2L UCSF GRCh37 13 113741572 113741572 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 23 47 0 ENST00000535094.2:c.2397G>A p.Lys799= p.K799= ENST00000535094 NM_001112732.2 799 aaG/aaA 0 +MCF2L2 UCSF GRCh37 3 183027568 183027568 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 75 150 0 ENST00000328913.3:c.1049G>A p.Gly350Glu p.G350E ENST00000328913 NM_015078.2 350 gGa/gAa 0 +MDN1 UCSF GRCh37 6 90383056 90383056 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 73 148 0 ENST00000369393.3:c.13373C>T p.Ala4458Val p.A4458V ENST00000369393 4458 gCa/gTa 0 +MED12L UCSF GRCh37 3 151148113 151148113 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 51 107 0 ENST00000474524.1:c.6330C>T p.Thr2110= p.T2110= ENST00000474524 NM_053002.4 2110 acC/acT 0 +MED13L UCSF GRCh37 12 116421027 116421027 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 62 135 0 ENST00000281928.3:c.4850G>A p.Ser1617Asn p.S1617N ENST00000281928 NM_015335.4 1617 aGc/aAc 0 +MED13L UCSF GRCh37 12 116443759 116443759 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 52 137 0 ENST00000281928.3:c.2384G>A p.Ser795Asn p.S795N ENST00000281928 NM_015335.4 795 aGt/aAt 0 +MED14 UCSF GRCh37 X 40531161 40531161 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 89 186 0 ENST00000324817.1:c.3085C>T p.His1029Tyr p.H1029Y ENST00000324817 NM_004229.3 1029 Cat/Tat 0 +MED14 UCSF GRCh37 X 40534551 40534551 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 56 139 0 ENST00000324817.1:c.2943C>T p.Asp981= p.D981= ENST00000324817 NM_004229.3 981 gaC/gaT 0 +MED14 UCSF GRCh37 X 40562802 40562802 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 51 103 0 ENST00000324817.1:c.1305C>T p.Leu435= p.L435= ENST00000324817 NM_004229.3 435 ctC/ctT 0 +MED23 UCSF GRCh37 6 131929203 131929203 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 77 152 0 ENST00000368068.3:c.1086G>A p.Gly362= p.G362= ENST00000368068 NM_004830.3 362 ggG/ggA 0 +MEGF11 UCSF GRCh37 15 66420670 66420670 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 17 29 0 ENST00000409699.2:c.72C>T p.Asp24= p.D24= ENST00000409699 24 gaC/gaT 0 +MEI1 UCSF GRCh37 22 42190449 42190449 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 129 232 0 ENST00000401548.3:c.3502C>T p.Leu1168Phe p.L1168F ENST00000401548 NM_152513.3 1168 Ctc/Ttc 0 +MESP1 UCSF GRCh37 15 90294045 90294045 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 8 15 0 ENST00000300057.4:c.418C>T p.Leu140= p.L140= ENST00000300057 NM_018670.3 140 Cta/Tta 0 +METTL10 UCSF GRCh37 10 126454016 126454017 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 0 ENST00000368836.2:c.561dup p.Leu188SerfsTer6 p.L188Sfs*6 ENST00000368836 NM_212554.2 187 ttt/ttTt 0 +METTL3 UCSF GRCh37 14 21971694 21971694 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 62 163 0 ENST00000298717.4:c.345G>A p.Gly115= p.G115= ENST00000298717 NM_019852.3 115 ggG/ggA 0 +METTL4 UCSF GRCh37 18 2547360 2547360 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 68 154 0 ENST00000574538.1:c.1068G>A p.Trp356Ter p.W356* ENST00000574538 NM_022840.3 356 tgG/tgA 0 +MEX3A UCSF GRCh37 1 156047225 156047225 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 16 58 0 ENST00000532414.2:c.703G>A p.Val235Met p.V235M ENST00000532414 NM_001093725.1 235 Gtg/Atg 0 +MFAP3L UCSF GRCh37 4 170913421 170913421 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 71 140 0 ENST00000361618.3:c.338C>T p.Thr113Ile p.T113I ENST00000361618 NM_021647.6 113 aCc/aTc 0 +MFHAS1 UCSF GRCh37 8 8749590 8749590 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 42 78 0 ENST00000276282.6:c.979G>A p.Asp327Asn p.D327N ENST00000276282 NM_004225.2 327 Gat/Aat 0 +MFSD7 UCSF GRCh37 4 680002 680002 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 27 67 0 ENST00000322224.4:c.384C>T p.Phe128= p.F128= ENST00000322224 128 ttC/ttT 0 +MGST2 UCSF GRCh37 4 140599723 140599723 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 46 98 0 ENST00000265498.1:c.85G>A p.Ala29Thr p.A29T ENST00000265498 NM_002413.4 29 Gca/Aca 0 +MICAL3 UCSF GRCh37 22 18362124 18362124 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 40 63 0 ENST00000441493.2:c.2241+6520C>T *747* ENST00000441493 NM_015241.2 0 +MINA UCSF GRCh37 3 97686406 97686406 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 38 98 0 ENST00000333396.7:c.32G>A p.Gly11Glu p.G11E ENST00000333396 NM_001042533.2 11 gGg/gAg 0 +MITF UCSF GRCh37 3 69987126 69987126 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 54 124 0 ENST00000352241.4:c.508C>T p.Pro170Ser p.P170S ENST00000352241 NM_198159.2 170 Cca/Tca 0 +MKRN2 UCSF GRCh37 3 12611623 12611623 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 64 115 0 ENST00000170447.7:c.209C>T p.Ala70Val p.A70V ENST00000170447 NM_014160.4 70 gCc/gTc 0 +MLH1 UCSF GRCh37 3 37090029 37090029 + missense_variant Missense_Mutation SNP C C T snp132_rs63749792 P10_Rec somatic WXS Sanger Illumina HiSeq 9 59 135 0 ENST00000231790.2:c.1918C>T p.Pro640Ser p.P640S ENST00000231790 NM_000249.3 640 Ccc/Tcc 0 +MLKL UCSF GRCh37 16 74706417 74706417 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 91 198 0 ENST00000308807.7:c.1401C>T p.Ser467= p.S467= ENST00000308807 NM_152649.2 467 tcC/tcT 0 +MLL UCSF GRCh37 11 118373395 118373395 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 73 161 0 ENST00000534358.1:c.6788C>T p.Thr2263Ile p.T2263I ENST00000534358 NM_005933.3 2263 aCt/aTt 0 +MLL2 UCSF GRCh37 12 49443496 49443496 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 60 110 0 ENST00000301067.7:c.3875G>A p.Arg1292His p.R1292H ENST00000301067 NM_003482.3 1292 cGc/cAc 0 +MLL2 UCSF GRCh37 12 49431862 49431862 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 51 122 0 ENST00000301067.7:c.9277C>T p.Pro3093Ser p.P3093S ENST00000301067 NM_003482.3 3093 Ccc/Tcc 0 +MLL2 UCSF GRCh37 12 49436429 49436429 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 46 126 0 ENST00000301067.7:c.5783-1G>A p.X1928_splice ENST00000301067 NM_003482.3 0 +MLL2 UCSF GRCh37 12 49416080 49416080 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 69 116 0 ENST00000301067.7:c.16395G>A p.Leu5465= p.L5465= ENST00000301067 NM_003482.3 5465 ttG/ttA 0 +MLL2 UCSF GRCh37 12 49435948 49435948 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 28 85 0 ENST00000301067.7:c.6033G>A p.Glu2011= p.E2011= ENST00000301067 NM_003482.3 2011 gaG/gaA 0 +MLL3 UCSF GRCh37 7 151851369 151851369 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 66 151 0 ENST00000262189.6:c.12122C>T p.Pro4041Leu p.P4041L ENST00000262189 NM_170606.2 4041 cCt/cTt 0 +MLL3 UCSF GRCh37 7 151884919 151884919 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 73 164 0 ENST00000262189.6:c.4674G>A p.Arg1558= p.R1558= ENST00000262189 NM_170606.2 1558 cgG/cgA 0 +MLL4 UCSF GRCh37 19 36210734 36210734 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 64 138 0 ENST00000222270.7:c.485C>T p.Pro162Leu p.P162L ENST00000222270 NM_014727.1 162 cCt/cTt 0 +MLLT10 UCSF GRCh37 10 21903804 21903804 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 31 92 0 ENST00000307729.7:c.554C>T p.Ala185Val p.A185V ENST00000307729 185 gCc/gTc 0 +MLLT10 UCSF GRCh37 10 21962612 21962612 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 221 100 213 0 ENST00000307729.7:c.1385C>T p.Thr462Ile p.T462I ENST00000307729 462 aCt/aTt 0 +MMACHC UCSF GRCh37 1 45973070 45973070 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 29 46 1 ENST00000401061.4:c.124C>T p.Pro42Ser p.P42S ENST00000401061 NM_015506.2 42 Ccg/Tcg 0 +MMP16 UCSF GRCh37 8 89058896 89058896 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 286 105 196 0 ENST00000286614.6:c.1489+1G>A p.X497_splice ENST00000286614 NM_005941.4 0 +MMP2 UCSF GRCh37 16 55525787 55525787 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 42 81 0 ENST00000219070.4:c.1255G>A p.Ala419Thr p.A419T ENST00000219070 NM_004530.4 419 Gcc/Acc 0 +MMP26 UCSF GRCh37 11 5010920 5010920 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 48 84 0 ENST00000380390.1:c.142C>T p.Leu48Phe p.L48F ENST00000380390 48 Ctc/Ttc 0 +MMRN1 UCSF GRCh37 4 90856881 90856881 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 84 153 0 ENST00000394980.1:c.2050G>A p.Ala684Thr p.A684T ENST00000394980 684 Gct/Act 0 +MMS22L UCSF GRCh37 6 97711230 97711230 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 75 157 0 ENST00000275053.4:c.923G>A p.Ser308Asn p.S308N ENST00000275053 NM_198468.2 308 aGt/aAt 0 +MOCOS UCSF GRCh37 18 33778720 33778720 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 37 96 0 ENST00000261326.5:c.299+1G>A p.X100_splice ENST00000261326 NM_017947.2 0 +MOCS1 UCSF GRCh37 6 39877675 39877675 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 58 123 0 ENST00000373186.4:c.1006G>A p.Val336Ile p.V336I ENST00000373186 NM_005943.5 336 Gta/Ata 0 +MON1A UCSF GRCh37 3 49946495 49946495 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 0 26 73 0 ENST00000296473.3:c.1911C>T p.Ile637= p.I637= ENST00000296473 NM_032355.3 637 atC/atT 0 +MON1B UCSF GRCh37 16 77227388 77227388 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 48 96 0 ENST00000248248.3:c.189G>A p.Pro63= p.P63= ENST00000248248 NM_014940.2 63 ccG/ccA 0 +MPP2 UCSF GRCh37 17 41958890 41958890 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 33 76 0 ENST00000269095.4:c.749G>A p.Gly250Asp p.G250D ENST00000269095 NM_001278374.1 250 gGc/gAc 0 +MPRIP UCSF GRCh37 17 17061919 17061919 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 38 38 0 ENST00000395811.5:c.1649C>T p.Pro550Leu p.P550L ENST00000395811 NM_015134.3 550 cCc/cTc 0 +MRGPRX1 UCSF GRCh37 11 18955369 18955369 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 78 295 0 ENST00000302797.3:c.963G>A p.Glu321= p.E321= ENST00000302797 NM_147199.3 321 gaG/gaA 0 +MRGPRX2 UCSF GRCh37 11 19077859 19077859 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 110 191 0 ENST00000329773.2:c.91C>T p.Leu31= p.L31= ENST00000329773 NM_054030.2 31 Ctg/Ttg 0 +MRGPRX3 UCSF GRCh37 11 18159399 18159399 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 66 142 0 ENST00000396275.2:c.650C>T p.Thr217Ile p.T217I ENST00000396275 NM_054031.3 217 aCc/aTc 0 +MRPL13 UCSF GRCh37 8 121426229 121426229 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 221 53 140 0 ENST00000306185.3:c.515+1G>A p.X172_splice ENST00000306185 NM_014078.5 0 +MRPL39 UCSF GRCh37 21 26960020 26960020 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 46 99 0 ENST00000307301.7:c.1051G>A p.Val351Ile p.V351I ENST00000307301 NM_080794.3 351 Gtc/Atc 0 +MRPL39 UCSF GRCh37 21 26978967 26978967 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 48 102 0 ENST00000307301.7:c.74G>A p.Arg25Lys p.R25K ENST00000307301 NM_080794.3 25 aGa/aAa 0 +MRPL41 UCSF GRCh37 9 140446606 140446606 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 13 20 0 ENST00000371443.5:c.73C>T p.Arg25Trp p.R25W ENST00000371443 NM_032477.2 25 Cgg/Tgg 0 +MRPL51 UCSF GRCh37 12 6602104 6602104 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 63 142 0 ENST00000229238.3:c.114C>T p.Leu38= p.L38= ENST00000229238 NM_016497.3 38 ctC/ctT 0 +MRPS22 UCSF GRCh37 3 139065749 139065749 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 80 185 0 ENST00000495075.1:c.202C>T p.Pro68Ser p.P68S ENST00000495075 68 Cct/Tct 0 +MS4A7 UCSF GRCh37 11 60156911 60156911 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 48 115 0 ENST00000300184.3:c.388G>A p.Ala130Thr p.A130T ENST00000300184 NM_206939.1 130 Gca/Aca 0 +MSI2 UCSF GRCh37 17 55693427 55693427 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 94 154 0 ENST00000284073.2:c.634C>T p.Leu212Phe p.L212F ENST00000284073 NM_138962.2 212 Ctt/Ttt 0 +MTA2 UCSF GRCh37 11 62362016 62362016 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 61 143 0 ENST00000278823.2:c.1664G>A p.Gly555Asp p.G555D ENST00000278823 NM_004739.3 555 gGc/gAc 0 +MTA3 UCSF GRCh37 2 42836678 42836678 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 150 113 213 0 ENST00000407270.3:c.271C>T p.Leu91Phe p.L91F ENST00000407270 NM_020744.2 91 Ctc/Ttc 0 +MTBP UCSF GRCh37 8 121457794 121457794 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 167 54 109 0 ENST00000305949.1:c.84G>A p.Glu28= p.E28= ENST00000305949 NM_022045.4 28 gaG/gaA 0 +MTERFD1 UCSF GRCh37 8 97263207 97263207 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 301 98 179 0 ENST00000287025.3:c.604G>A p.Asp202Asn p.D202N ENST00000287025 NM_015942.3 202 Gat/Aat 0 +MTERFD3 UCSF GRCh37 12 107371758 107371758 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 99 177 0 ENST00000552029.1:c.735C>T p.Leu245= p.L245= ENST00000552029 245 ctC/ctT 0 +MTFMT UCSF GRCh37 15 65313862 65313862 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 101 197 0 ENST00000220058.4:c.635G>A p.Gly212Asp p.G212D ENST00000220058 NM_139242.3 212 gGt/gAt 0 +MTMR11 UCSF GRCh37 1 149905829 149905829 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 112 127 212 0 ENST00000439741.2:c.690C>T p.Pro230= p.P230= ENST00000439741 NM_001145862.1 230 ccC/ccT 0 +MUC12 UCSF GRCh37 7 100634404 100634404 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 141 112 207 0 ENST00000536621.1:c.560C>T p.Pro187Leu p.P187L ENST00000536621 NM_001164462.1 187 cCa/cTa 0 +MUC12 UCSF GRCh37 7 100636003 100636003 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 305 112 500 0 ENST00000536621.1:c.2159G>A p.Ser720Asn p.S720N ENST00000536621 NM_001164462.1 720 aGc/aAc 0 +MUC16 UCSF GRCh37 19 9065187 9065187 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 113 218 0 ENST00000397910.4:c.22259C>T p.Ala7420Val p.A7420V ENST00000397910 NM_024690.2 7420 gCt/gTt 0 +MUC16 UCSF GRCh37 19 9088766 9088766 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 154 148 234 0 ENST00000397910.4:c.3049C>T p.Pro1017Ser p.P1017S ENST00000397910 NM_024690.2 1017 Cca/Tca 0 +MUC4 UCSF GRCh37 3 195507918 195507918 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 514 109 606 0 ENST00000463781.3:c.10533C>T p.Ser3511= p.S3511= ENST00000463781 NM_018406.6 3511 tcC/tcT 0 +MUC6 UCSF GRCh37 11 1017468 1017468 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 184 90 639 0 ENST00000421673.2:c.5333C>T p.Thr1778Ile p.T1778I ENST00000421673 NM_005961.2 1778 aCc/aTc 0 +MVK UCSF GRCh37 12 110028600 110028600 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 40 95 0 ENST00000228510.3:c.702G>A p.Leu234= p.L234= ENST00000228510 NM_001114185.1 234 ctG/ctA 0 +MYBL1 UCSF GRCh37 8 67478442 67478442 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 65 142 0 ENST00000522677.3:c.1987C>T p.Pro663Ser p.P663S ENST00000522677 NM_001080416.2 663 Cca/Tca 0 +MYBPC2 UCSF GRCh37 19 50940918 50940918 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 65 107 0 ENST00000357701.5:c.515G>A p.Ser172Asn p.S172N ENST00000357701 NM_004533.3 172 aGt/aAt 0 +MYBPH UCSF GRCh37 1 203138040 203138040 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 96 194 0 ENST00000255416.4:c.1411G>A p.Val471Ile p.V471I ENST00000255416 NM_004997.2 471 Gtc/Atc 0 +MYCN UCSF GRCh37 2 16085664 16085664 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 24 46 0 ENST00000281043.3:c.840C>T p.Val280= p.V280= ENST00000281043 NM_005378.4 280 gtC/gtT 0 +MYF6 UCSF GRCh37 12 81101749 81101749 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 56 83 1 ENST00000228641.3:c.251C>T p.Thr84Ile p.T84I ENST00000228641 NM_002469.2 84 aCc/aTc 0 +MYH1 UCSF GRCh37 17 10411716 10411716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 77 182 0 ENST00000226207.5:c.1861G>A p.Ala621Thr p.A621T ENST00000226207 NM_005963.3 621 Gct/Act 0 +MYH1 UCSF GRCh37 17 10406468 10406468 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 54 218 1 ENST00000226207.5:c.2789C>A p.Ala930Asp p.A930D ENST00000226207 NM_005963.3 930 gCt/gAt 0 +MYH1 UCSF GRCh37 17 10411855 10411855 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 117 202 0 ENST00000226207.5:c.1722C>T p.Gly574= p.G574= ENST00000226207 NM_005963.3 574 ggC/ggT 0 +MYH14 UCSF GRCh37 19 50764778 50764778 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 13 55 0 ENST00000601313.1:c.2471G>A p.Ser824Asn p.S824N ENST00000601313 NM_001145809.1 824 aGc/aAc 0 +MYH3 UCSF GRCh37 17 10532992 10532992 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 55 157 0 ENST00000583535.1:c.5718G>A p.Glu1906= p.E1906= ENST00000583535 NM_002470.3 1906 gaG/gaA 0 +MYH3 UCSF GRCh37 17 10555770 10555770 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 66 157 0 ENST00000583535.1:c.315C>T p.Asn105= p.N105= ENST00000583535 NM_002470.3 105 aaC/aaT 0 +MYH4 UCSF GRCh37 17 10369707 10369707 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 114 194 0 ENST00000255381.2:c.231C>T p.Val77= p.V77= ENST00000255381 NM_017533.2 77 gtC/gtT 0 +MYH8 UCSF GRCh37 17 10322311 10322311 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 132 75 166 0 ENST00000403437.2:c.247A>G p.Asn83Asp p.N83D ENST00000403437 NM_002472.2 83 Aac/Gac 0 +MYH8 UCSF GRCh37 17 10310022 10310022 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 66 161 0 ENST00000403437.2:c.2156G>A p.Gly719Asp p.G719D ENST00000403437 NM_002472.2 719 gGt/gAt 0 +MYLK3 UCSF GRCh37 16 46766561 46766561 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 18 13 0 ENST00000394809.4:c.1021G>A p.Glu341Lys p.E341K ENST00000394809 NM_182493.2 341 Gag/Aag 0 +MYNN UCSF GRCh37 3 169496819 169496819 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 81 127 0 ENST00000349841.5:c.530C>T p.Ser177Phe p.S177F ENST00000349841 NM_018657.4 177 tCt/tTt 0 +MYO10 UCSF GRCh37 5 16761595 16761595 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 59 127 0 ENST00000513610.1:c.1717C>T p.Leu573Phe p.L573F ENST00000513610 NM_012334.2 573 Ctc/Ttc 0 +MYO15A UCSF GRCh37 17 18077205 18077205 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 28 43 0 ENST00000205890.5:c.10461C>T p.Ala3487= p.A3487= ENST00000205890 NM_016239.3 3487 gcC/gcT 0 +MYO18B UCSF GRCh37 22 26422559 26422559 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 141 219 0 ENST00000335473.7:c.6619G>A p.Asp2207Asn p.D2207N ENST00000335473 NM_032608.5 2207 Gac/Aac 0 +MYO1D UCSF GRCh37 17 31082612 31082612 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 58 130 0 ENST00000318217.5:c.1365C>T p.Ile455= p.I455= ENST00000318217 NM_015194.1 455 atC/atT 0 +MYO1G UCSF GRCh37 7 45010558 45010558 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 14 47 0 ENST00000258787.7:c.947C>T p.Ala316Val p.A316V ENST00000258787 NM_033054.2 316 gCc/gTc 0 +MYO1H UCSF GRCh37 12 109847811 109847811 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 42 91 0 ENST00000310903.5:c.1219C>T p.Gln407Ter p.Q407* ENST00000310903 407 Caa/Taa 0 +MYO5A UCSF GRCh37 15 52611418 52611418 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 73 156 1 ENST00000399231.3:c.4998G>A p.Arg1666= p.R1666= ENST00000399231 NM_000259.3 1666 cgG/cgA 0 +MYO7A UCSF GRCh37 11 76917230 76917230 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 20 66 0 ENST00000409709.3:c.5725C>T p.Pro1909Ser p.P1909S ENST00000409709 NM_000260.3 1909 Cct/Tct 0 +MYO7A UCSF GRCh37 11 76853811 76853811 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 27 55 0 ENST00000409709.3:c.75G>A p.Gly25= p.G25= ENST00000409709 NM_000260.3 25 ggG/ggA 0 +MYO9A UCSF GRCh37 15 72170512 72170512 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 58 142 0 ENST00000356056.5:c.5800G>A p.Glu1934Lys p.E1934K ENST00000356056 NM_006901.3 1934 Gaa/Aaa 0 +MYO9A UCSF GRCh37 15 72122464 72122464 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 94 187 0 ENST00000356056.5:c.7026C>T p.Asn2342= p.N2342= ENST00000356056 NM_006901.3 2342 aaC/aaT 0 +MYOG UCSF GRCh37 1 203054982 203054982 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 49 82 0 ENST00000241651.4:c.108G>A p.Glu36= p.E36= ENST00000241651 NM_002479.5 36 gaG/gaA 0 +MYOM2 UCSF GRCh37 8 2017412 2017412 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 49 101 0 ENST00000262113.4:c.669C>T p.Asp223= p.D223= ENST00000262113 NM_003970.2 223 gaC/gaT 0 +MYOM3 UCSF GRCh37 1 24406551 24406551 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 46 104 0 ENST00000374434.3:c.2541G>A p.Gln847= p.Q847= ENST00000374434 NM_152372.3 847 caG/caA 0 +N4BP1 UCSF GRCh37 16 48596018 48596018 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 117 220 1 ENST00000262384.3:c.536C>T p.Pro179Leu p.P179L ENST00000262384 NM_153029.3 179 cCc/cTc 0 +N4BP2 UCSF GRCh37 4 40121568 40121568 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 57 128 0 ENST00000261435.6:c.1837G>A p.Asp613Asn p.D613N ENST00000261435 NM_018177.4 613 Gat/Aat 0 +NAA16 UCSF GRCh37 13 41894916 41894916 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 67 139 0 ENST00000379406.3:c.358C>T p.Leu120Phe p.L120F ENST00000379406 NM_024561.4 120 Ctc/Ttc 0 +NAA16 UCSF GRCh37 13 41893038 41893038 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 51 91 0 ENST00000379406.3:c.236G>A p.Ser79Asn p.S79N ENST00000379406 NM_024561.4 79 aGt/aAt 0 +NACA UCSF GRCh37 12 57114999 57114999 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 39 75 0 ENST00000550952.1:c.315C>T p.Asn105= p.N105= ENST00000550952 105 aaC/aaT 0 +NACAD UCSF GRCh37 7 45122972 45122972 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 22 76 0 ENST00000490531.2:c.2807G>A p.Gly936Asp p.G936D ENST00000490531 NM_001146334.1 936 gGt/gAt 0 +NACC1 UCSF GRCh37 19 13246135 13246135 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 32 57 0 ENST00000292431.4:c.114C>T p.Gly38= p.G38= ENST00000292431 NM_052876.3 38 ggC/ggT 0 +NAPG UCSF GRCh37 18 10533534 10533534 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 17 62 0 ENST00000322897.6:c.211C>T p.Leu71Phe p.L71F ENST00000322897 NM_003826.2 71 Ctt/Ttt 0 +NAPRT1 UCSF GRCh37 8 144660099 144660099 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 19 43 0 ENST00000449291.2:c.241G>A p.Ala81Thr p.A81T ENST00000449291 81 Gcc/Acc 0 +NAPRT1 UCSF GRCh37 8 144657681 144657681 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 26 68 0 ENST00000449291.2:c.1203G>A p.Gly401= p.G401= ENST00000449291 401 ggG/ggA 0 +NARS2 UCSF GRCh37 11 78282414 78282414 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 42 103 0 ENST00000281038.5:c.217C>T p.Leu73Phe p.L73F ENST00000281038 NM_001243251.1 73 Ctt/Ttt 0 +NBAS UCSF GRCh37 2 15629017 15629017 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 103 214 0 ENST00000281513.5:c.1083+1G>A p.X361_splice ENST00000281513 NM_015909.3 0 +NBAS UCSF GRCh37 2 15601325 15601325 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 62 143 0 ENST00000281513.5:c.2339G>A p.Cys780Tyr p.C780Y ENST00000281513 NM_015909.3 780 tGt/tAt 0 +NBEA UCSF GRCh37 13 36180590 36180590 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 73 178 0 ENST00000400445.3:c.7324C>T p.Pro2442Ser p.P2442S ENST00000400445 NM_015678.4 2442 Cca/Tca 0 +NBEA UCSF GRCh37 13 35747630 35747630 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 70 158 0 ENST00000400445.3:c.4453G>A p.Glu1485Lys p.E1485K ENST00000400445 NM_015678.4 1485 Gaa/Aaa 0 +NBEAL2 UCSF GRCh37 3 47041495 47041495 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 61 89 0 ENST00000450053.3:c.3906C>T p.Pro1302= p.P1302= ENST00000450053 NM_015175.2 1302 ccC/ccT 0 +NBPF1 UCSF GRCh37 1 16902964 16902964 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 546 63 861 0 ENST00000430580.2:c.1917C>T p.Val639= p.V639= ENST00000430580 NM_017940.4 639 gtC/gtT 0 +NCAN UCSF GRCh37 19 19330107 19330107 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 14 17 0 ENST00000252575.6:c.457G>A p.Val153Met p.V153M ENST00000252575 NM_004386.2 153 Gtg/Atg 0 +NCAN UCSF GRCh37 19 19339079 19339079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 75 127 0 ENST00000252575.6:c.2650G>A p.Val884Ile p.V884I ENST00000252575 NM_004386.2 884 Gtt/Att 0 +NCAPD2 UCSF GRCh37 12 6626819 6626819 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 49 44 121 0 ENST00000315579.5:c.1378A>G p.Met460Val p.M460V ENST00000315579 NM_014865.3 460 Atg/Gtg 0 +NCAPD2 UCSF GRCh37 12 6626830 6626830 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 38 110 0 ENST00000315579.5:c.1389G>A p.Gln463= p.Q463= ENST00000315579 NM_014865.3 463 caG/caA 0 +NCAPD2 UCSF GRCh37 12 6634766 6634766 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 56 109 0 ENST00000315579.5:c.2232G>A p.Gln744= p.Q744= ENST00000315579 NM_014865.3 744 caG/caA 0 +NCAPG2 UCSF GRCh37 7 158445019 158445019 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 156 110 194 0 ENST00000409423.1:c.2900G>A p.Arg967Gln p.R967Q ENST00000409423 NM_001281932.1 967 cGg/cAg 0 +NCF2 UCSF GRCh37 1 183559494 183559494 + 5_prime_UTR_variant 5'UTR SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 48 72 0 ENST00000367535.3:c.-30C>T *10* ENST00000367535 NM_000433.3 0 +NCF2 UCSF GRCh37 1 183532372 183532372 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 53 132 0 ENST00000367535.3:c.1248G>A p.Gln416= p.Q416= ENST00000367535 NM_000433.3 416 caG/caA 0 +NCKAP1L UCSF GRCh37 12 54929930 54929930 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 56 154 0 ENST00000293373.6:c.2974G>A p.Glu992Lys p.E992K ENST00000293373 NM_005337.4 992 Gag/Aag 0 +NCLN UCSF GRCh37 19 3207468 3207468 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 51 70 0 ENST00000246117.4:c.1632+1G>A p.X544_splice ENST00000246117 NM_020170.3 0 +NCOR1 UCSF GRCh37 17 16042446 16042446 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 18 79 0 ENST00000268712.3:c.1228G>A p.Ala410Thr p.A410T ENST00000268712 NM_006311.3 410 Gca/Aca 0 +NDUFA5 UCSF GRCh37 7 123190599 123190599 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 98 159 0 ENST00000355749.2:c.108G>A p.Glu36= p.E36= ENST00000355749 NM_005000.2 36 gaG/gaA 0 +NDUFA8 UCSF GRCh37 9 124906657 124906657 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 121 45 120 0 ENST00000373768.3:c.382G>A p.Val128Ile p.V128I ENST00000373768 NM_014222.2 128 Gtc/Atc 0 +NDUFB1 UCSF GRCh37 14 92583900 92583900 + missense_variant Missense_Mutation SNP C C G NOVEL P10_Rec Untested WXS Illumina HiSeq 50 45 110 0 ENST00000329559.3:c.223G>C p.Asp75His p.D75H ENST00000329559 NM_004545.3 75 Gac/Cac 0 +NDUFB8 UCSF GRCh37 10 102286283 102286283 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 53 100 0 ENST00000299166.4:c.341G>A p.Arg114Lys p.R114K ENST00000299166 NM_005004.2 114 aGg/aAg 0 +NDUFB9 UCSF GRCh37 8 125551466 125551466 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 178 58 112 0 ENST00000276689.3:c.39G>A p.Gln13= p.Q13= ENST00000276689 NM_001278646.1 13 caG/caA 0 +NEB UCSF GRCh37 2 152550904 152550904 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0011 P10_Rec Untested WXS Illumina HiSeq 156 139 243 0 ENST00000397345.3:c.1829G>A p.Gly610Glu p.G610E ENST00000397345 NM_001164508.1 610 gGa/gAa 0 +NEB UCSF GRCh37 2 152490274 152490274 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 134 131 220 0 ENST00000397345.3:c.9308C>T p.Thr3103Ile p.T3103I ENST00000397345 NM_001164508.1 3103 aCc/aTc 0 +NEGR1 UCSF GRCh37 1 72400806 72400806 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 46 97 0 ENST00000357731.5:c.365C>T p.Thr122Ile p.T122I ENST00000357731 NM_173808.2 122 aCt/aTt 0 +NEIL1 UCSF GRCh37 15 75641296 75641296 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 30 53 0 ENST00000564784.1:c.50C>T p.Ala17Val p.A17V ENST00000564784 17 gCc/gTc 0 +NEK6 UCSF GRCh37 9 127101923 127101923 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 85 103 0 ENST00000373600.3:c.798C>T p.Ser266= p.S266= ENST00000373600 NM_001145001.2 266 tcC/tcT 0 +NES UCSF GRCh37 1 156640343 156640343 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 76 144 0 ENST00000368223.3:c.3637G>A p.Asp1213Asn p.D1213N ENST00000368223 NM_006617.1 1213 Gat/Aat 0 +NES UCSF GRCh37 1 156642923 156642923 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 32 71 0 ENST00000368223.3:c.1057C>T p.Pro353Ser p.P353S ENST00000368223 NM_006617.1 353 Cca/Tca 0 +NET1 UCSF GRCh37 10 5488735 5488735 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 50 96 0 ENST00000355029.4:c.256-5058G>A *86* ENST00000355029 NM_001047160.2 0 +NEURL4 UCSF GRCh37 17 7227496 7227496 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 48 99 0 ENST00000399464.2:c.1993C>T p.Pro665Ser p.P665S ENST00000399464 NM_032442.2 665 Ccc/Tcc 0 +NFAT5 UCSF GRCh37 16 69727984 69727984 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 95 60 140 0 ENST00000432919.1:c.4256C>T p.Pro1419Leu p.P1419L ENST00000432919 NM_138713.3 1419 cCt/cTt 0 +NFATC2 UCSF GRCh37 20 50049043 50049043 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 24 30 0 ENST00000396009.3:c.2283C>T p.Ser761= p.S761= ENST00000396009 NM_001258297.1 761 agC/agT 0 +NFKB1 UCSF GRCh37 4 103528456 103528456 + missense_variant Missense_Mutation SNP G G A snp132_rs111293796 P10_Rec Untested WXS Illumina HiSeq 71 69 113 0 ENST00000226574.4:c.2104G>A p.Ala702Thr p.A702T ENST00000226574 NM_003998.3 702 Gca/Aca 0 +NFKB2 UCSF GRCh37 10 104156010 104156010 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 41 80 0 ENST00000369966.3:c.22G>A p.Gly8Ser p.G8S ENST00000369966 NM_001077494.2 8 Ggt/Agt 0 +NFRKB UCSF GRCh37 11 129755479 129755479 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 43 70 0 ENST00000524794.1:c.530G>A p.Ser177Asn p.S177N ENST00000524794 177 aGt/aAt 0 +NFYA UCSF GRCh37 6 41048556 41048556 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 44 108 0 ENST00000341376.6:c.82G>A p.Gly28Ser p.G28S ENST00000341376 NM_002505.4 28 Ggt/Agt 0 +NGFR UCSF GRCh37 17 47590187 47590187 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 42 87 0 ENST00000172229.3:c.1100G>A p.Gly367Asp p.G367D ENST00000172229 NM_002507.3 367 gGc/gAc 0 +NID2 UCSF GRCh37 14 52496330 52496330 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 59 121 0 ENST00000216286.5:c.2336G>A p.Gly779Glu p.G779E ENST00000216286 NM_007361.3 779 gGg/gAg 0 +NINJ2 UCSF GRCh37 12 772650 772650 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 66 130 0 ENST00000305108.4:c.15C>T p.Ser5= p.S5= ENST00000305108 NM_016533.4 5 tcC/tcT 0 +NKAPL UCSF GRCh37 6 28227951 28227951 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 36 96 0 ENST00000343684.3:c.802C>T p.Gln268Ter p.Q268* ENST00000343684 NM_001007531.2 268 Cag/Tag 0 +NLGN4X UCSF GRCh37 X 5947330 5947330 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 89 177 0 ENST00000381095.3:c.616G>A p.Gly206Arg p.G206R ENST00000381095 NM_181332.1 206 Gga/Aga 0 +NLGN4X UCSF GRCh37 X 5821576 5821576 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 55 150 0 ENST00000381095.3:c.1143C>T p.Asp381= p.D381= ENST00000381095 NM_181332.1 381 gaC/gaT 0 +NLRP4 UCSF GRCh37 19 56390315 56390315 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 27 60 0 ENST00000301295.6:c.2852C>T p.Ala951Val p.A951V ENST00000301295 NM_134444.4 951 gCc/gTc 0 +NLRP4 UCSF GRCh37 19 56370596 56370596 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 49 179 0 ENST00000301295.6:c.1837G>A p.Glu613Lys p.E613K ENST00000301295 NM_134444.4 613 Gag/Aag 0 +NLRX1 UCSF GRCh37 11 119054035 119054035 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 52 111 0 ENST00000409109.1:c.2815G>A p.Asp939Asn p.D939N ENST00000409109 NM_001282144.1 939 Gat/Aat 0 +NLRX1 UCSF GRCh37 11 119052980 119052980 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 58 88 0 ENST00000409109.1:c.2532C>T p.Tyr844= p.Y844= ENST00000409109 NM_001282144.1 844 taC/taT 0 +NME4 UCSF GRCh37 16 450246 450246 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 46 127 0 ENST00000219479.2:c.468G>A p.Val156= p.V156= ENST00000219479 NM_005009.2 156 gtG/gtA 0 +NOC2L UCSF GRCh37 1 894347 894347 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 44 60 0 ENST00000327044.6:c.141C>T p.Ala47= p.A47= ENST00000327044 NM_015658.3 47 gcC/gcT 0 +NOD2 UCSF GRCh37 16 50745116 50745116 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 69 96 0 ENST00000300589.2:c.1294G>A p.Ala432Thr p.A432T ENST00000300589 NM_022162.1 432 Gcg/Acg 0 +NOL8 UCSF GRCh37 9 95083950 95083950 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 13 41 0 ENST00000545558.1:c.281G>A p.Arg94Lys p.R94K ENST00000545558 94 aGa/aAa 0 +NONO UCSF GRCh37 X 70510605 70510605 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 53 110 0 ENST00000276079.8:c.118C>T p.Pro40Ser p.P40S ENST00000276079 NM_007363.4 40 Cca/Tca 0 +NONO UCSF GRCh37 X 70518341 70518341 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 110 196 0 ENST00000276079.8:c.1154G>A p.Gly385Asp p.G385D ENST00000276079 NM_007363.4 385 gGt/gAt 0 +NOP2 UCSF GRCh37 12 6677046 6677046 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 62 102 0 ENST00000382421.3:c.39G>A p.Gly13= p.G13= ENST00000382421 NM_001258309.1 13 ggG/ggA 0 +NOTCH1 UCSF GRCh37 9 139395012 139395012 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 47 76 0 ENST00000277541.6:c.5926G>A p.Val1976Ile p.V1976I ENST00000277541 NM_017617.3 1976 Gtc/Atc 0 +NOTCH2 UCSF GRCh37 1 120466339 120466339 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 51 137 0 ENST00000256646.2:c.4780G>A p.Gly1594Ser p.G1594S ENST00000256646 NM_024408.3 1594 Ggt/Agt 0 +NOTCH4 UCSF GRCh37 6 32168734 32168734 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 38 65 0 ENST00000375023.3:c.4189C>T p.Pro1397Ser p.P1397S ENST00000375023 NM_004557.3 1397 Ccg/Tcg 0 +NOTCH4 UCSF GRCh37 6 32187934 32187934 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 45 66 0 ENST00000375023.3:c.1287C>T p.Cys429= p.C429= ENST00000375023 NM_004557.3 429 tgC/tgT 0 +NPAS1 UCSF GRCh37 19 47535576 47535576 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 30 72 0 ENST00000602212.1:c.399C>T p.Val133= p.V133= ENST00000602212 133 gtC/gtT 0 +NPAS2 UCSF GRCh37 2 101606778 101606778 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 59 101 0 ENST00000335681.5:c.1888C>T p.Leu630= p.L630= ENST00000335681 NM_002518.3 630 Cta/Tta 0 +NPC2 UCSF GRCh37 14 74953067 74953067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 16 14 33 0 ENST00000555619.1:c.155G>A p.Gly52Glu p.G52E ENST00000555619 NM_006432.3 52 gGa/gAa 0 +NPEPL1 UCSF GRCh37 20 57288599 57288599 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 29 59 0 ENST00000356091.6:c.1125G>A p.Gln375= p.Q375= ENST00000356091 NM_024663.3 375 caG/caA 0 +NPHP3 UCSF GRCh37 3 132419247 132419247 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 80 202 0 ENST00000337331.5:c.1674C>T p.Ser558= p.S558= ENST00000337331 NM_153240.4 558 tcC/tcT 0 +NPHS2 UCSF GRCh37 1 179521766 179521766 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 28 61 0 ENST00000367615.4:c.845C>T p.Ala282Val p.A282V ENST00000367615 NM_014625.2 282 gCt/gTt 0 +NPM3 UCSF GRCh37 10 103541607 103541607 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 81 172 0 ENST00000370110.5:c.423G>A p.Thr141= p.T141= ENST00000370110 NM_006993.2 141 acG/acA 0 +NPR2 UCSF GRCh37 9 35806481 35806481 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 65 131 0 ENST00000342694.2:c.2465C>T p.Ala822Val p.A822V ENST00000342694 NM_003995.3 822 gCc/gTc 0 +NQO2 UCSF GRCh37 6 3019826 3019826 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 60 110 0 ENST00000338130.2:c.633G>A p.Arg211= p.R211= ENST00000338130 211 agG/agA 0 +NR1H2 UCSF GRCh37 19 50880868 50880868 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 41 99 0 ENST00000253727.5:c.6C>T p.Ser2= p.S2= ENST00000253727 NM_007121.5 2 tcC/tcT 0 +NR1I2 UCSF GRCh37 3 119529028 119529028 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 12 34 0 ENST00000337940.4:c.435C>T p.Gly145= p.G145= ENST00000337940 NM_022002.2 145 ggC/ggT 0 +NR1I3 UCSF GRCh37 1 161199705 161199705 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 48 114 0 ENST00000367980.2:c.956C>T p.Ala319Val p.A319V ENST00000367980 NM_001077481.2 319 gCg/gTg 0 +NRIP1 UCSF GRCh37 21 16338166 16338166 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 82 169 0 ENST00000400202.1:c.2348G>A p.Gly783Asp p.G783D ENST00000400202 783 gGt/gAt 0 +NRK UCSF GRCh37 X 105139427 105139427 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 114 138 0 ENST00000428173.2:c.491G>A p.Gly164Asp p.G164D ENST00000428173 164 gGc/gAc 0 +NRXN1 UCSF GRCh37 2 50149265 50149265 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 62 132 0 ENST00000404971.1:c.4461C>T p.Ile1487= p.I1487= ENST00000404971 NM_001135659.1 1487 atC/atT 0 +NRXN2 UCSF GRCh37 11 64418013 64418013 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 75 140 0 ENST00000265459.6:c.3016G>A p.Val1006Met p.V1006M ENST00000265459 NM_015080.3 1006 Gtg/Atg 0 +NSD1 UCSF GRCh37 5 176562676 176562676 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 98 222 0 ENST00000439151.2:c.572C>T p.Ala191Val p.A191V ENST00000439151 NM_022455.4 191 gCc/gTc 0 +NSD1 UCSF GRCh37 5 176562370 176562370 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 76 168 0 ENST00000439151.2:c.266G>A p.Gly89Glu p.G89E ENST00000439151 NM_022455.4 89 gGg/gAg 0 +NSF UCSF GRCh37 17 44788375 44788375 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 59 166 0 ENST00000398238.4:c.1517G>A p.Gly506Asp p.G506D ENST00000398238 NM_006178.3 506 gGt/gAt 0 +NSUN7 UCSF GRCh37 4 40778101 40778101 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 43 161 0 ENST00000381782.2:c.861G>A p.Lys287= p.K287= ENST00000381782 NM_024677.4 287 aaG/aaA 0 +NT5C2 UCSF GRCh37 10 104934647 104934647 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 88 177 0 ENST00000343289.5:c.69C>T p.Ala23= p.A23= ENST00000343289 NM_012229.4 23 gcC/gcT 0 +NTNG2 UCSF GRCh37 9 135073502 135073502 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 35 90 0 ENST00000393229.3:c.363C>T p.Ala121= p.A121= ENST00000393229 NM_032536.2 121 gcC/gcT 0 +NTRK2 UCSF GRCh37 9 87482194 87482194 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 167 89 150 0 ENST00000277120.3:c.1481C>T p.Ala494Val p.A494V ENST00000277120 494 gCc/gTc 0 +NUDT21 UCSF GRCh37 16 56481862 56481862 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 59 122 0 ENST00000300291.5:c.156C>T p.Pro52= p.P52= ENST00000300291 NM_007006.2 52 ccC/ccT 0 +NUMB UCSF GRCh37 14 73749202 73749202 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 39 64 0 ENST00000355058.3:c.961G>A p.Glu321Lys p.E321K ENST00000355058 321 Gaa/Aaa 0 +NUMB UCSF GRCh37 14 73789900 73789900 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 34 88 0 ENST00000355058.3:c.139G>A p.Val47Ile p.V47I ENST00000355058 47 Gta/Ata 0 +NUP107 UCSF GRCh37 12 69125440 69125440 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 48 130 0 ENST00000229179.4:c.1939G>A p.Asp647Asn p.D647N ENST00000229179 NM_020401.2 647 Gat/Aat 0 +NUP107 UCSF GRCh37 12 69125424 69125424 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 44 110 0 ENST00000229179.4:c.1923G>A p.Glu641= p.E641= ENST00000229179 NM_020401.2 641 gaG/gaA 0 +NUP133 UCSF GRCh37 1 229588355 229588355 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 53 131 0 ENST00000261396.3:c.3016G>A p.Glu1006Lys p.E1006K ENST00000261396 NM_018230.2 1006 Gag/Aag 0 +NUP133 UCSF GRCh37 1 229643896 229643896 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 20 43 0 ENST00000261396.3:c.101G>A p.Arg34Lys p.R34K ENST00000261396 NM_018230.2 34 aGg/aAg 0 +NUP153 UCSF GRCh37 6 17661921 17661921 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 79 215 0 ENST00000262077.2:c.1358G>A p.Arg453Lys p.R453K ENST00000262077 NM_001278210.1 453 aGa/aAa 0 +NUP155 UCSF GRCh37 5 37328498 37328498 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 45 121 0 ENST00000231498.3:c.1838C>T p.Pro613Leu p.P613L ENST00000231498 NM_153485.2 613 cCc/cTc 0 +NUP210 UCSF GRCh37 3 13432778 13432778 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 21 55 0 ENST00000254508.5:c.466G>A p.Val156Ile p.V156I ENST00000254508 NM_024923.3 156 Gtc/Atc 0 +NUP88 UCSF GRCh37 17 5290097 5290097 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 120 86 220 0 ENST00000573584.1:c.2093G>A p.Ser698Asn p.S698N ENST00000573584 NM_002532.4 698 aGt/aAt 0 +NXF1 UCSF GRCh37 11 62563641 62563641 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 92 185 0 ENST00000532297.1:c.1358G>A p.Arg453Gln p.R453Q ENST00000532297 453 cGg/cAg 0 +NXF3 UCSF GRCh37 X 102334323 102334323 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 142 124 237 1 ENST00000395065.3:c.1299C>T p.Asp433= p.D433= ENST00000395065 NM_022052.1 433 gaC/gaT 0 +NXNL1 UCSF GRCh37 19 17566756 17566756 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 10 21 0 ENST00000301944.2:c.339C>T p.Arg113= p.R113= ENST00000301944 NM_138454.1 113 cgC/cgT 0 +OAS1 UCSF GRCh37 12 113354501 113354501 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 69 175 0 ENST00000445409.2:c.842C>T p.Pro281Leu p.P281L ENST00000445409 NM_001032409.1 281 cCc/cTc 0 +OAS1 UCSF GRCh37 12 113354419 113354419 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 65 137 0 ENST00000445409.2:c.760G>A p.Gly254Arg p.G254R ENST00000445409 NM_001032409.1 254 Gga/Aga 0 +OBSCN UCSF GRCh37 1 228461576 228461576 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 24 43 0 ENST00000570156.2:c.6368C>T p.Ala2123Val p.A2123V ENST00000570156 NM_001271223.2 2123 gCc/gTc 0 +OBSCN UCSF GRCh37 1 228522236 228522236 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 15 16 0 ENST00000570156.2:c.18949C>T p.Pro6317Ser p.P6317S ENST00000570156 NM_001271223.2 6317 Cct/Tct 0 +OBSCN UCSF GRCh37 1 228552705 228552705 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 9 23 0 ENST00000570156.2:c.21736C>T p.Pro7246Ser p.P7246S ENST00000570156 NM_001271223.2 7246 Ccc/Tcc 0 +OBSCN UCSF GRCh37 1 228557687 228557687 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 33 73 0 ENST00000570156.2:c.22883C>T p.Thr7628Ile p.T7628I ENST00000570156 NM_001271223.2 7628 aCc/aTc 0 +OBSCN UCSF GRCh37 1 228559004 228559004 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 10 25 0 ENST00000570156.2:c.23396C>T p.Ser7799Phe p.S7799F ENST00000570156 NM_001271223.2 7799 tCc/tTc 0 +OBSCN UCSF GRCh37 1 228432260 228432260 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 91 161 0 ENST00000570156.2:c.3745C>T p.Leu1249= p.L1249= ENST00000570156 NM_001271223.2 1249 Ctg/Ttg 0 +OBSL1 UCSF GRCh37 2 220423059 220423059 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 15 28 0 ENST00000404537.1:c.3349G>A p.Asp1117Asn p.D1117N ENST00000404537 NM_015311.2 1117 Gac/Aac 0 +OCRL UCSF GRCh37 X 128691333 128691333 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 50 123 0 ENST00000371113.4:c.270G>A p.Trp90Ter p.W90* ENST00000371113 NM_000276.3 90 tgG/tgA 0 +ODF3L2 UCSF GRCh37 19 463950 463950 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 17 28 0 ENST00000315489.4:c.764C>T p.Ala255Val p.A255V ENST00000315489 NM_182577.2 255 gCt/gTt 0 +ODZ1 UCSF GRCh37 X 123539019 123539019 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 74 141 0 ENST00000422452.2:c.5253C>T p.Ile1751= p.I1751= ENST00000422452 NM_001163279.1 1751 atC/atT 0 +ODZ1 UCSF GRCh37 X 123540204 123540204 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 116 116 198 0 ENST00000422452.2:c.5118C>T p.Asn1706= p.N1706= ENST00000422452 NM_001163279.1 1706 aaC/aaT 0 +ODZ1 UCSF GRCh37 X 123556420 123556420 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 70 169 0 ENST00000422452.2:c.4173C>T p.Asn1391= p.N1391= ENST00000422452 NM_001163279.1 1391 aaC/aaT 0 +ODZ2 UCSF GRCh37 5 167689120 167689120 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 64 128 0 ENST00000518659.1:c.7630G>A p.Val2544Ile p.V2544I ENST00000518659 NM_001122679.1 2544 Gtc/Atc 0 +ODZ3 UCSF GRCh37 4 183664402 183664402 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 100 202 0 ENST00000511685.1:c.3459G>A p.Gly1153= p.G1153= ENST00000511685 1153 ggG/ggA 0 +ODZ4 UCSF GRCh37 11 78433848 78433848 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 71 169 0 ENST00000278550.7:c.3665G>A p.Gly1222Asp p.G1222D ENST00000278550 NM_001098816.2 1222 gGc/gAc 0 +OFD1 UCSF GRCh37 X 13764556 13764556 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 105 209 0 ENST00000340096.6:c.636G>A p.Arg212= p.R212= ENST00000340096 NM_003611.2 212 cgG/cgA 0 +OGDHL UCSF GRCh37 10 50948755 50948755 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 19 46 0 ENST00000374103.4:c.2140+1G>A p.X714_splice ENST00000374103 NM_018245.2 0 +OGT UCSF GRCh37 X 70757678 70757678 + splice_acceptor_variant Splice_Site SNP G G T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 81 167 0 ENST00000373719.3:c.219-1G>T p.X73_splice ENST00000373719 NM_181673.2 0 +OPLAH UCSF GRCh37 8 145109807 145109807 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 25 50 0 ENST00000426825.1:c.2419C>T p.Leu807= p.L807= ENST00000426825 NM_017570.3 807 Ctg/Ttg 0 +OR10G2 UCSF GRCh37 14 22102456 22102456 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 80 169 0 ENST00000542433.1:c.543C>T p.Tyr181= p.Y181= ENST00000542433 NM_001005466.1 181 taC/taT 0 +OR10G9 UCSF GRCh37 11 123894090 123894090 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 62 170 0 ENST00000375024.1:c.371C>T p.Ala124Val p.A124V ENST00000375024 NM_001001953.1 124 gCc/gTc 0 +OR10K1 UCSF GRCh37 1 158435940 158435940 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 133 201 0 ENST00000289451.2:c.589C>T p.Leu197= p.L197= ENST00000289451 NM_001004473.1 197 Ctg/Ttg 0 +OR10K1 UCSF GRCh37 1 158436158 158436158 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 107 209 0 ENST00000289451.2:c.807C>T p.Ser269= p.S269= ENST00000289451 NM_001004473.1 269 agC/agT 0 +OR13C8 UCSF GRCh37 9 107331735 107331735 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 179 107 195 0 ENST00000335040.1:c.287G>A p.Gly96Glu p.G96E ENST00000335040 NM_001004483.1 96 gGg/gAg 0 +OR2G6 UCSF GRCh37 1 248684977 248684977 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 105 87 183 0 ENST00000343414.4:c.30G>A p.Lys10= p.K10= ENST00000343414 NM_001013355.1 10 aaG/aaA 0 +OR2J3 UCSF GRCh37 6 29080164 29080164 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 118 210 0 ENST00000377169.1:c.497C>T p.Thr166Ile p.T166I ENST00000377169 NM_001005216.3 166 aCc/aTc 0 +OR2T27 UCSF GRCh37 1 248814051 248814051 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 11 110 0 ENST00000344889.3:c.135G>A p.Lys45= p.K45= ENST00000344889 NM_001001824.1 45 aaG/aaA 0 +OR4B1 UCSF GRCh37 11 48238562 48238562 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 110 199 0 ENST00000309562.2:c.201G>A p.Val67= p.V67= ENST00000309562 NM_001005470.1 67 gtG/gtA 0 +OR4C3 UCSF GRCh37 11 48347418 48347418 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 18 253 0 ENST00000319856.4:c.926C>T p.Pro309Leu p.P309L ENST00000319856 NM_001004702.1 309 cCa/cTa 0 +OR4K13 UCSF GRCh37 14 20502272 20502272 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 79 161 0 ENST00000315693.2:c.646G>A p.Val216Ile p.V216I ENST00000315693 NM_001004714.1 216 Gtc/Atc 0 +OR4N4 UCSF GRCh37 15 22382483 22382483 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 206 96 236 0 ENST00000328795.4:c.11C>T p.Ala4Val p.A4V ENST00000328795 NM_001005241.2 4 gCa/gTa 0 +OR4Q3 UCSF GRCh37 14 20216283 20216283 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 179 84 202 1 ENST00000331723.1:c.697G>A p.Gly233Ser p.G233S ENST00000331723 NM_172194.1 233 Ggc/Agc 0 +OR51L1 UCSF GRCh37 11 5020514 5020514 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 121 187 0 ENST00000321543.1:c.302C>T p.Ala101Val p.A101V ENST00000321543 NM_001004755.1 101 gCt/gTt 0 +OR52A5 UCSF GRCh37 11 5153120 5153120 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 93 193 0 ENST00000307388.1:c.753C>T p.Phe251= p.F251= ENST00000307388 NM_001005160.2 251 ttC/ttT 0 +OR5AK2 UCSF GRCh37 11 56757227 56757227 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 79 173 0 ENST00000326855.2:c.839C>T p.Thr280Ile p.T280I ENST00000326855 NM_001005323.1 280 aCa/aTa 0 +OR5L2 UCSF GRCh37 11 55595176 55595176 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 138 221 0 ENST00000378397.1:c.482C>T p.Ser161Phe p.S161F ENST00000378397 NM_001004739.1 161 tCc/tTc 0 +OR5P3 UCSF GRCh37 11 7847083 7847083 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 80 174 0 ENST00000328375.1:c.437G>A p.Gly146Asp p.G146D ENST00000328375 NM_153445.1 146 gGc/gAc 0 +OR6S1 UCSF GRCh37 14 21109787 21109787 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 102 195 0 ENST00000320704.3:c.64C>T p.Leu22Phe p.L22F ENST00000320704 NM_001001968.1 22 Ctc/Ttc 0 +OR6T1 UCSF GRCh37 11 123813611 123813611 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 104 216 0 ENST00000321252.2:c.935C>T p.Ala312Val p.A312V ENST00000321252 NM_001005187.1 312 gCt/gTt 0 +OR7C2 UCSF GRCh37 19 15053082 15053082 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 90 186 0 ENST00000248072.3:c.782C>T p.Ser261Phe p.S261F ENST00000248072 NM_012377.1 261 tCt/tTt 0 +OR9K2 UCSF GRCh37 12 55524499 55524499 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 79 168 0 ENST00000305377.5:c.947G>A p.Arg316Lys p.R316K ENST00000305377 NM_001005243.1 316 aGg/aAg 0 +OR9Q1 UCSF GRCh37 11 57947297 57947297 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 60 159 0 ENST00000335397.3:c.381C>T p.Cys127= p.C127= ENST00000335397 NM_001005212.3 127 tgC/tgT 0 +ORC1 UCSF GRCh37 1 52840505 52840505 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 23 87 0 ENST00000371568.3:c.2368C>T p.Leu790= p.L790= ENST00000371568 NM_001190818.1 790 Ctg/Ttg 0 +OSBP UCSF GRCh37 11 59344079 59344079 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 137 130 240 0 ENST00000263847.1:c.2395G>A p.Asp799Asn p.D799N ENST00000263847 NM_002556.2 799 Gac/Aac 0 +OSBPL9 UCSF GRCh37 1 52231629 52231629 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 65 142 0 ENST00000447887.1:c.944G>A p.Gly315Asp p.G315D ENST00000447887 315 gGc/gAc 0 +OTC UCSF GRCh37 X 38271253 38271253 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 89 223 0 ENST00000039007.4:c.1005+1G>A p.X335_splice ENST00000039007 NM_000531.5 0 +OTC UCSF GRCh37 X 38229063 38229063 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 56 134 0 ENST00000039007.4:c.231G>A p.Leu77= p.L77= ENST00000039007 NM_000531.5 77 ttG/ttA 0 +OTOF UCSF GRCh37 2 26690087 26690087 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 78 113 0 ENST00000272371.2:c.4242G>A p.Glu1414= p.E1414= ENST00000272371 NM_194248.2 1414 gaG/gaA 0 +OTOF UCSF GRCh37 2 26696403 26696403 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 31 70 0 ENST00000272371.2:c.3441G>A p.Arg1147= p.R1147= ENST00000272371 NM_194248.2 1147 cgG/cgA 0 +OTOL1 UCSF GRCh37 3 161214879 161214879 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 138 95 243 0 ENST00000327928.4:c.284C>T p.Ala95Val p.A95V ENST00000327928 NM_001080440.1 95 gCt/gTt 0 +OTOP2 UCSF GRCh37 17 72927040 72927040 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 67 96 0 ENST00000331427.4:c.1310C>T p.Thr437Ile p.T437I ENST00000331427 NM_178160.2 437 aCc/aTc 0 +OTUD7B UCSF GRCh37 1 149931686 149931686 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 68 131 0 ENST00000369135.4:c.762G>A p.Trp254Ter p.W254* ENST00000369135 NM_020205.3 254 tgG/tgA 0 +P2RY11 UCSF GRCh37 19 10225389 10225389 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 31 64 0 ENST00000321826.4:c.1100C>T p.Pro367Leu p.P367L ENST00000321826 NM_002566.4 367 cCc/cTc 0 +P2RY2 UCSF GRCh37 11 72945864 72945864 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 34 56 0 ENST00000311131.2:c.660C>T p.Leu220= p.L220= ENST00000311131 NM_176072.2 220 ctC/ctT 0 +P2RY2 UCSF GRCh37 11 72946126 72946126 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 62 98 0 ENST00000311131.2:c.922C>T p.Leu308= p.L308= ENST00000311131 NM_176072.2 308 Ctg/Ttg 0 +PABPC3 UCSF GRCh37 13 25671444 25671444 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 133 87 194 0 ENST00000281589.3:c.1108C>T p.Arg370Cys p.R370C ENST00000281589 NM_030979.2 370 Cgc/Tgc 0 +PABPC4 UCSF GRCh37 1 40038140 40038140 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 94 76 183 0 ENST00000372858.3:c.312G>A p.Lys104= p.K104= ENST00000372858 NM_001135653.1 104 aaG/aaA 0 +PACRGL UCSF GRCh37 4 20706157 20706157 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 39 112 0 ENST00000503585.1:c.52+1G>A p.X18_splice ENST00000503585 NM_001258345.1 0 +PADI3 UCSF GRCh37 1 17592181 17592181 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 46 147 0 ENST00000375460.3:c.374G>A p.Cys125Tyr p.C125Y ENST00000375460 NM_016233.2 125 tGt/tAt 0 +PAF1 UCSF GRCh37 19 39880350 39880350 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 92 146 0 ENST00000221265.3:c.222C>T p.Leu74= p.L74= ENST00000221265 NM_019088.3 74 ctC/ctT 0 +PAK1 UCSF GRCh37 11 77064613 77064613 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 61 160 0 ENST00000356341.3:c.804G>A p.Lys268= p.K268= ENST00000356341 NM_002576.4 268 aaG/aaA 0 +PAK7 UCSF GRCh37 20 9561506 9561506 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 74 172 0 ENST00000353224.5:c.276C>T p.Ile92= p.I92= ENST00000353224 NM_177990.2 92 atC/atT 0 +PALM3 UCSF GRCh37 19 14166215 14166215 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 6 26 0 ENST00000340790.4:c.377C>T p.Ser126Phe p.S126F ENST00000340790 NM_001145028.1 126 tCc/tTc 0 +PAOX UCSF GRCh37 10 135197700 135197700 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 58 117 0 ENST00000278060.5:c.1105G>A p.Val369Ile p.V369I ENST00000278060 NM_152911.2 369 Gtc/Atc 0 +PAPD7 UCSF GRCh37 5 6738823 6738823 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 84 193 0 ENST00000230859.6:c.118G>A p.Gly40Ser p.G40S ENST00000230859 NM_001171805.1 40 Ggt/Agt 0 +PAPLN UCSF GRCh37 14 73726113 73726113 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 33 54 0 ENST00000340738.5:c.1764C>T p.Pro588= p.P588= ENST00000340738 NM_173462.3 588 ccC/ccT 0 +PAQR6 UCSF GRCh37 1 156215982 156215982 + 5_prime_UTR_variant 5'UTR SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 28 71 0 ENST00000335852.1:c.-343C>T *115* ENST00000335852 NM_024897.3 0 +PAQR9 UCSF GRCh37 3 142681301 142681301 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 57 89 0 ENST00000340634.3:c.878G>A p.Ser293Asn p.S293N ENST00000340634 NM_198504.2 293 aGc/aAc 0 +PARD3 UCSF GRCh37 10 34408598 34408598 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 18 35 0 ENST00000374789.3:c.3620G>A p.Arg1207Gln p.R1207Q ENST00000374789 NM_019619.3 1207 cGg/cAg 0 +PARD3B UCSF GRCh37 2 206480410 206480410 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 70 168 0 ENST00000358768.2:c.3305C>T p.Pro1102Leu p.P1102L ENST00000358768 1102 cCc/cTc 0 +PARP10 UCSF GRCh37 8 145060340 145060340 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 172 45 61 0 ENST00000313028.7:c.64G>A p.Val22Met p.V22M ENST00000313028 NM_032789.3 22 Gtg/Atg 0 +PARP10 UCSF GRCh37 8 145059662 145059662 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 28 52 0 ENST00000313028.7:c.591C>T p.Arg197= p.R197= ENST00000313028 NM_032789.3 197 cgC/cgT 0 +PARP8 UCSF GRCh37 5 50090071 50090071 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 83 57 162 0 ENST00000281631.5:c.768G>A p.Trp256Ter p.W256* ENST00000281631 NM_024615.3 256 tgG/tgA 0 +PARP9 UCSF GRCh37 3 122274837 122274837 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 85 123 0 ENST00000360356.2:c.286G>A p.Val96Ile p.V96I ENST00000360356 NM_001146102.1 96 Gtc/Atc 0 +PARS2 UCSF GRCh37 1 55223689 55223689 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 82 142 0 ENST00000371279.3:c.1146G>A p.Lys382= p.K382= ENST00000371279 NM_152268.3 382 aaG/aaA 0 +PAX8 UCSF GRCh37 2 114002187 114002187 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 67 152 0 ENST00000429538.3:c.206G>A p.Gly69Asp p.G69D ENST00000429538 NM_003466.3 69 gGc/gAc 0 +PAX8 UCSF GRCh37 2 113984731 113984731 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 11 17 0 ENST00000429538.3:c.1189+1G>A p.X397_splice ENST00000429538 NM_003466.3 0 +PAXIP1 UCSF GRCh37 7 154767540 154767540 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 84 155 0 ENST00000404141.1:c.940G>A p.Ala314Thr p.A314T ENST00000404141 314 Gct/Act 0 +PBK UCSF GRCh37 8 27690588 27690588 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 31 85 0 ENST00000301905.4:c.43G>A p.Glu15Lys p.E15K ENST00000301905 NM_001278945.1 15 Gaa/Aaa 0 +PCDH18 UCSF GRCh37 4 138452772 138452772 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 90 126 0 ENST00000344876.4:c.471C>T p.Pro157= p.P157= ENST00000344876 NM_019035.3 157 ccC/ccT 0 +PCDHA3 UCSF GRCh37 5 140182340 140182340 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 75 113 0 ENST00000522353.2:c.1558C>T p.Leu520= p.L520= ENST00000522353 NM_018906.2 520 Ctg/Ttg 0 +PCDHA3 UCSF GRCh37 5 140181988 140181988 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 83 191 0 ENST00000522353.2:c.1206G>A p.Lys402= p.K402= ENST00000522353 NM_018906.2 402 aaG/aaA 0 +PCDHA5 UCSF GRCh37 5 140201429 140201429 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 62 132 0 ENST00000529859.1:c.69G>A p.Trp23Ter p.W23* ENST00000529859 NM_018908.2 23 tgG/tgA 0 +PCDHA6 UCSF GRCh37 5 140208723 140208723 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 82 83 204 0 ENST00000529310.1:c.1047G>A p.Glu349= p.E349= ENST00000529310 NM_018909.2 349 gaG/gaA 0 +PCDHA7 UCSF GRCh37 5 140214435 140214435 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 99 35 174 0 ENST00000525929.1:c.467G>A p.Gly156Asp p.G156D ENST00000525929 NM_018910.2 156 gGc/gAc 0 +PCDHA9 UCSF GRCh37 5 140228547 140228547 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 33 88 0 ENST00000532602.1:c.467G>A p.Gly156Asp p.G156D ENST00000532602 NM_031857.1 156 gGc/gAc 0 +PCDHB5 UCSF GRCh37 5 140517039 140517039 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 56 126 0 ENST00000231134.5:c.2023G>A p.Ala675Thr p.A675T ENST00000231134 NM_015669.2 675 Gcg/Acg 0 +PCDHB9 UCSF GRCh37 5 140567134 140567134 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 56 152 0 ENST00000316105.4:n.242C>T *81* ENST00000316105 0 +PCDHB9 UCSF GRCh37 5 140567721 140567721 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 42 84 0 ENST00000316105.4:n.829G>A *277* ENST00000316105 0 +PCDHGB1 UCSF GRCh37 5 140732149 140732149 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 40 83 0 ENST00000523390.1:c.2322G>A p.Gln774= p.Q774= ENST00000523390 NM_018922.2 774 caG/caA 0 +PCDHGB4 UCSF GRCh37 5 140768177 140768177 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 135 111 214 0 ENST00000519479.1:c.726C>T p.Phe242= p.F242= ENST00000519479 NM_003736.2 242 ttC/ttT 0 +PCDHGB7 UCSF GRCh37 5 140797671 140797671 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 98 77 157 1 ENST00000398594.2:c.245G>A p.Gly82Glu p.G82E ENST00000398594 NM_018927.3 82 gGg/gAg 0 +PCDHGC3 UCSF GRCh37 5 140856768 140856768 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 55 92 0 ENST00000308177.3:c.1085C>T p.Pro362Leu p.P362L ENST00000308177 NM_002588.2 362 cCc/cTc 0 +PCDP1 UCSF GRCh37 2 120413987 120413987 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 31 94 0 ENST00000413369.3:c.2464C>T p.Leu822Phe p.L822F ENST00000413369 NM_001271049.1 822 Ctc/Ttc 0 +PCK1 UCSF GRCh37 20 56140507 56140507 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 73 158 0 ENST00000319441.4:c.1516G>A p.Ala506Thr p.A506T ENST00000319441 NM_002591.3 506 Gcc/Acc 0 +PCNT UCSF GRCh37 21 47783713 47783713 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 55 128 0 ENST00000359568.5:c.2473G>A p.Glu825Lys p.E825K ENST00000359568 NM_006031.5 825 Gaa/Aaa 0 +PCNX UCSF GRCh37 14 71485788 71485788 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 114 90 200 0 ENST00000304743.2:c.3059G>A p.Gly1020Glu p.G1020E ENST00000304743 NM_014982.2 1020 gGa/gAa 0 +PCYT1B UCSF GRCh37 X 24625961 24625961 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 21 61 0 ENST00000379144.2:c.235G>A p.Val79Ile p.V79I ENST00000379144 NM_004845.4 79 Gta/Ata 0 +PDC UCSF GRCh37 1 186413413 186413413 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 128 119 246 0 ENST00000391997.2:c.439G>A p.Gly147Ser p.G147S ENST00000391997 NM_002597.4 147 Ggt/Agt 0 +PDCD6 UCSF GRCh37 5 306740 306740 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 76 126 0 ENST00000264933.4:c.232G>A p.Ala78Thr p.A78T ENST00000264933 NM_001267556.1 78 Gcc/Acc 0 +PDE2A UCSF GRCh37 11 72294554 72294554 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 36 97 0 ENST00000334456.5:c.1656C>T p.Leu552= p.L552= ENST00000334456 NM_002599.4 552 ctC/ctT 0 +PDE4A UCSF GRCh37 19 10531444 10531444 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 10 8 0 ENST00000352831.6:c.4G>A p.Glu2Lys p.E2K ENST00000352831 NM_001111307.1 2 Gaa/Aaa 0 +PDE4DIP UCSF GRCh37 1 144859782 144859782 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 111 24 156 1 ENST00000369356.4:c.6302G>A p.Gly2101Glu p.G2101E ENST00000369356 NM_014644.5 2101 gGa/gAa 0 +PDE4DIP UCSF GRCh37 1 145075649 145075649 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 64 10 48 0 ENST00000369345.4:c.214G>A p.Ala72Thr p.A72T ENST00000369345 72 Gcg/Acg 0 +PDE4DIP UCSF GRCh37 1 144864250 144864250 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 235 90 343 0 ENST00000369356.4:c.5845G>A p.Glu1949Lys p.E1949K ENST00000369356 NM_014644.5 1949 Gag/Aag 0 +PDE4DIP UCSF GRCh37 1 144917570 144917570 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 318 111 387 0 ENST00000369356.4:c.1534G>A p.Ala512Thr p.A512T ENST00000369356 NM_014644.5 512 Gct/Act 0 +PDE4DIP UCSF GRCh37 1 144857006 144857006 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 33 148 0 ENST00000369356.4:c.6479C>T p.Pro2160Leu p.P2160L ENST00000369356 NM_014644.5 2160 cCt/cTt 0 +PDE6B UCSF GRCh37 4 619530 619530 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 42 87 0 ENST00000496514.1:c.115G>A p.Gly39Arg p.G39R ENST00000496514 39 Ggg/Agg 0 +PDE6B UCSF GRCh37 4 657987 657987 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 30 51 0 ENST00000496514.1:c.2106G>A p.Glu702= p.E702= ENST00000496514 702 gaG/gaA 0 +PDE9A UCSF GRCh37 21 44171225 44171225 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 113 230 0 ENST00000291539.6:c.654-1G>A p.X218_splice ENST00000291539 NM_002606.2 0 +PDGFRB UCSF GRCh37 5 149516589 149516589 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 20 52 0 ENST00000261799.4:c.22C>T p.Pro8Ser p.P8S ENST00000261799 NM_002609.3 8 Cca/Tca 0 +PDIA2 UCSF GRCh37 16 334467 334467 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 8 29 0 ENST00000219406.6:c.280G>A p.Val94Met p.V94M ENST00000219406 NM_006849.2 94 Gtg/Atg 0 +PDIA5 UCSF GRCh37 3 122880194 122880194 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 46 105 0 ENST00000316218.7:c.1371C>T p.Val457= p.V457= ENST00000316218 NM_006810.3 457 gtC/gtT 0 +PDK2 UCSF GRCh37 17 48187335 48187335 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 10 5 16 0 ENST00000503176.1:c.1098C>T p.Asp366= p.D366= ENST00000503176 NM_002611.4 366 gaC/gaT 0 +PDLIM5 UCSF GRCh37 4 95376501 95376501 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 23 73 0 ENST00000514743.1:c.62G>A p.Gly21Asp p.G21D ENST00000514743 NM_001256426.1 21 gGt/gAt 0 +PDPR UCSF GRCh37 16 70162947 70162947 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 326 114 411 0 ENST00000288050.4:c.529G>A p.Ala177Thr p.A177T ENST00000288050 NM_017990.3 177 Gcc/Acc 0 +PDPR UCSF GRCh37 16 70176293 70176293 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 157 57 220 1 ENST00000288050.4:c.1471+1G>A p.X491_splice ENST00000288050 NM_017990.3 0 +PDS5B UCSF GRCh37 13 33222964 33222964 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 55 150 0 ENST00000315596.10:c.55G>A p.Val19Ile p.V19I ENST00000315596 NM_015032.3 19 Gtc/Atc 0 +PDZD2 UCSF GRCh37 5 32090465 32090465 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 67 162 0 ENST00000438447.1:c.6911C>T p.Thr2304Met p.T2304M ENST00000438447 2304 aCg/aTg 0 +PEAK1 UCSF GRCh37 15 77407640 77407640 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 57 131 0 ENST00000560626.2:c.4099G>A p.Glu1367Lys p.E1367K ENST00000560626 1367 Gaa/Aaa 0 +PEAK1 UCSF GRCh37 15 77425714 77425714 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 100 174 0 ENST00000560626.2:c.3710G>A p.Ser1237Asn p.S1237N ENST00000560626 1237 aGc/aAc 0 +PECR UCSF GRCh37 2 216946456 216946456 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 29 59 0 ENST00000265322.7:c.9C>T p.Ser3= p.S3= ENST00000265322 NM_018441.5 3 tcC/tcT 0 +PEG3 UCSF GRCh37 19 57327209 57327209 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 81 168 0 ENST00000326441.9:c.2601C>T p.Asp867= p.D867= ENST00000326441 NM_006210.2 867 gaC/gaT 0 +PER2 UCSF GRCh37 2 239165610 239165610 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 43 133 0 ENST00000254657.3:c.2018G>A p.Ser673Asn p.S673N ENST00000254657 NM_022817.2 673 aGc/aAc 0 +PER2 UCSF GRCh37 2 239170986 239170986 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 47 103 0 ENST00000254657.3:c.1154-1G>A p.X385_splice ENST00000254657 NM_022817.2 0 +PEX13 UCSF GRCh37 2 61259071 61259071 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 100 75 163 0 ENST00000295030.5:c.610G>A p.Gly204Ser p.G204S ENST00000295030 NM_002618.3 204 Ggc/Agc 0 +PEX5L UCSF GRCh37 3 179597902 179597902 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 45 98 0 ENST00000467460.1:c.320C>T p.Thr107Ile p.T107I ENST00000467460 NM_001256751.1 107 aCt/aTt 0 +PEX6 UCSF GRCh37 6 42933057 42933057 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 42 90 0 ENST00000304611.8:c.2521G>A p.Asp841Asn p.D841N ENST00000304611 NM_000287.3 841 Gat/Aat 0 +PFKP UCSF GRCh37 10 3147617 3147617 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 46 110 0 ENST00000381125.4:c.698G>A p.Gly233Asp p.G233D ENST00000381125 NM_002627.4 233 gGt/gAt 0 +PFN2 UCSF GRCh37 3 149686298 149686298 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 91 181 0 ENST00000239940.7:c.172G>A p.Gly58Ser p.G58S ENST00000239940 58 Ggt/Agt 0 +PGBD1 UCSF GRCh37 6 28253422 28253422 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 37 48 120 0 ENST00000405948.2:c.491G>A p.Gly164Glu p.G164E ENST00000405948 NM_001184743.1 164 gGg/gAg 0 +PGBD2 UCSF GRCh37 1 249212463 249212463 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 79 153 0 ENST00000329291.5:c.1680G>A p.Arg560= p.R560= ENST00000329291 NM_170725.2 560 agG/agA 0 +PGCP UCSF GRCh37 8 97892204 97892204 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 312 76 203 0 ENST00000220763.5:c.820G>A p.Glu274Lys p.E274K ENST00000220763 NM_016134.3 274 Gag/Aag 0 +PGS1 UCSF GRCh37 17 76399989 76399989 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 73 102 0 ENST00000262764.6:c.1221G>A p.Gln407= p.Q407= ENST00000262764 NM_024419.3 407 caG/caA 0 +PHACTR2 UCSF GRCh37 6 144070135 144070135 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 30 74 0 ENST00000440869.2:c.228G>A p.Lys76= p.K76= ENST00000440869 NM_001100164.1 76 aaG/aaA 0 +PHB UCSF GRCh37 17 47482379 47482379 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 8 18 0 ENST00000300408.3:c.794C>T p.Ser265Phe p.S265F ENST00000300408 NM_002634.3 265 tCc/tTc 0 +PHF12 UCSF GRCh37 17 27233388 27233388 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 44 76 0 ENST00000332830.4:c.2828G>A p.Gly943Asp p.G943D ENST00000332830 NM_001033561.1 943 gGc/gAc 0 +PHF23 UCSF GRCh37 17 7139077 7139077 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 110 166 0 ENST00000320316.3:c.1080G>A p.Gly360= p.G360= ENST00000320316 NM_024297.2 360 ggG/ggA 0 +PHKA1 UCSF GRCh37 X 71843054 71843054 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 58 150 0 ENST00000373542.4:c.1865G>A p.Gly622Glu p.G622E ENST00000373542 NM_002637.3 622 gGa/gAa 0 +PHKG1 UCSF GRCh37 7 56151003 56151003 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 39 72 0 ENST00000452681.2:c.611C>T p.Ser204Phe p.S204F ENST00000452681 NM_001258459.1 204 tCc/tTc 0 +PHLDB1 UCSF GRCh37 11 118502183 118502183 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 10 29 0 ENST00000361417.2:c.2087G>A p.Ser696Asn p.S696N ENST00000361417 NM_015157.3 696 aGc/aAc 0 +PHLPP1 UCSF GRCh37 18 60527681 60527681 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 183 42 215 0 ENST00000262719.5:c.1913G>A p.Arg638His p.R638H ENST00000262719 638 cGc/cAc 0 +PHTF1 UCSF GRCh37 1 114242401 114242401 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 10 24 0 ENST00000369604.1:c.2067G>A p.Met689Ile p.M689I ENST00000369604 689 atG/atA 0 +PI4KA UCSF GRCh37 22 21096956 21096956 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 55 106 0 ENST00000255882.6:c.3553C>T p.His1185Tyr p.H1185Y ENST00000255882 NM_058004.3 1185 Cat/Tat 0 +PI4KB UCSF GRCh37 1 151278774 151278774 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 49 129 0 ENST00000368875.2:c.1284C>T p.Ala428= p.A428= ENST00000368875 NM_002651.2 428 gcC/gcT 0 +PIAS4 UCSF GRCh37 19 4028595 4028595 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 20 33 0 ENST00000262971.2:c.669C>T p.Val223= p.V223= ENST00000262971 NM_015897.2 223 gtC/gtT 0 +PIEZO1 UCSF GRCh37 16 88792793 88792793 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 9 17 0 ENST00000301015.9:c.3867C>T p.Ser1289= p.S1289= ENST00000301015 NM_001142864.2 1289 agC/agT 0 +PIEZO2 UCSF GRCh37 18 10672871 10672871 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 50 112 0 ENST00000503781.3:c.7823-1G>A p.X2608_splice ENST00000503781 NM_022068.2 0 +PIGS UCSF GRCh37 17 26898094 26898094 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 43 81 0 ENST00000308360.7:c.147C>T p.Ser49= p.S49= ENST00000308360 NM_033198.3 49 tcC/tcT 0 +PIGT UCSF GRCh37 20 44048995 44048995 + missense_variant Missense_Mutation SNP T T A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 32 44 0 ENST00000279036.6:c.793T>A p.Ser265Thr p.S265T ENST00000279036 NM_015937.5 265 Tcc/Acc 0 +PIK3C3 UCSF GRCh37 18 39613797 39613797 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 57 156 0 ENST00000262039.4:c.1715G>A p.Arg572Lys p.R572K ENST00000262039 NM_002647.2 572 aGa/aAa 0 +PIK3C3 UCSF GRCh37 18 39584421 39584421 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 32 91 0 ENST00000262039.4:c.1086C>T p.Asp362= p.D362= ENST00000262039 NM_002647.2 362 gaC/gaT 0 +PJA2 UCSF GRCh37 5 108714805 108714805 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 80 157 0 ENST00000361189.2:c.383G>A p.Gly128Asp p.G128D ENST00000361189 NM_014819.4 128 gGc/gAc 0 +PKD1 UCSF GRCh37 16 2152522 2152522 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 48 73 0 ENST00000262304.4:c.9061G>A p.Glu3021Lys p.E3021K ENST00000262304 NM_001009944.2 3021 Gag/Aag 0 +PKD1L1 UCSF GRCh37 7 47897327 47897327 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 62 62 106 0 ENST00000289672.2:c.4466T>C p.Val1489Ala p.V1489A ENST00000289672 NM_138295.3 1489 gTg/gCg 0 +PKD1L2 UCSF GRCh37 16 81145904 81145904 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 95 135 1 ENST00000525539.1:c.6847C>T p.Pro2283Ser p.P2283S ENST00000525539 NM_052892.3 2283 Cca/Tca 0 +PKD1L3 UCSF GRCh37 16 71988149 71988149 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 81 178 0 ENST00000534738.1:n.2664G>A *888* ENST00000534738 0 +PKHD1 UCSF GRCh37 6 51735337 51735337 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 50 120 0 ENST00000371117.3:c.7451C>T p.Ala2484Val p.A2484V ENST00000371117 NM_138694.3 2484 gCc/gTc 0 +PKHD1 UCSF GRCh37 6 51920389 51920389 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 34 102 0 ENST00000371117.3:c.1832C>T p.Thr611Ile p.T611I ENST00000371117 NM_138694.3 611 aCa/aTa 0 +PKHD1 UCSF GRCh37 6 51720715 51720715 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 82 225 0 ENST00000371117.3:c.7887C>T p.Asn2629= p.N2629= ENST00000371117 NM_138694.3 2629 aaC/aaT 0 +PKHD1L1 UCSF GRCh37 8 110396319 110396319 + synonymous_variant Silent SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 389 55 213 0 ENST00000378402.5:c.438A>G p.Pro146= p.P146= ENST00000378402 NM_177531.4 146 ccA/ccG 0 +PKN3 UCSF GRCh37 9 131469082 131469082 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 13 27 0 ENST00000291906.4:c.502G>A p.Ala168Thr p.A168T ENST00000291906 NM_013355.3 168 Gcc/Acc 0 +PLAC4 UCSF GRCh37 21 42551485 42551485 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 14 22 0 ENST00000330333.6:c.312+10983G>A *104* ENST00000330333 NM_012105.4 0 +PLCB1 UCSF GRCh37 20 8609010 8609010 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 55 147 0 ENST00000338037.6:c.316G>A p.Val106Met p.V106M ENST00000338037 NM_015192.3 106 Gtg/Atg 0 +PLCB1 UCSF GRCh37 20 8696941 8696941 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 34 95 0 ENST00000338037.6:c.1281C>T p.Tyr427= p.Y427= ENST00000338037 NM_015192.3 427 taC/taT 0 +PLCB2 UCSF GRCh37 15 40594532 40594532 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 36 52 0 ENST00000260402.3:c.391C>T p.Leu131= p.L131= ENST00000260402 NM_004573.2 131 Ctg/Ttg 0 +PLCD4 UCSF GRCh37 2 219487450 219487450 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 132 102 223 0 ENST00000450993.2:c.621G>A p.Glu207= p.E207= ENST00000450993 NM_032726.3 207 gaG/gaA 0 +PLCE1 UCSF GRCh37 10 96005837 96005837 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 60 109 0 ENST00000371380.3:c.2555C>T p.Ser852Phe p.S852F ENST00000371380 852 tCc/tTc 0 +PLCL1 UCSF GRCh37 2 198949169 198949169 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 113 199 0 ENST00000428675.1:c.928C>T p.Leu310Phe p.L310F ENST00000428675 NM_006226.3 310 Ctt/Ttt 0 +PLD3 UCSF GRCh37 19 40883792 40883792 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 33 65 0 ENST00000409587.1:c.1285G>A p.Gly429Arg p.G429R ENST00000409587 429 Gga/Aga 0 +PLEC UCSF GRCh37 8 144991766 144991766 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 257 60 81 0 ENST00000322810.4:c.12634G>A p.Glu4212Lys p.E4212K ENST00000322810 NM_201380.2 4212 Gag/Aag 0 +PLEC UCSF GRCh37 8 144993812 144993812 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 28 40 0 ENST00000322810.4:c.10588G>A p.Ala3530Thr p.A3530T ENST00000322810 NM_201380.2 3530 Gcg/Acg 0 +PLEC UCSF GRCh37 8 144997025 144997025 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 16 18 0 ENST00000322810.4:c.7483G>A p.Ala2495Thr p.A2495T ENST00000322810 NM_201380.2 2495 Gcg/Acg 0 +PLEC UCSF GRCh37 8 145001197 145001197 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 24 29 0 ENST00000322810.4:c.4304C>T p.Ser1435Phe p.S1435F ENST00000322810 NM_201380.2 1435 tCc/tTc 0 +PLEC UCSF GRCh37 8 145006824 145006824 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 25 52 0 ENST00000322810.4:c.2205C>T p.Asp735= p.D735= ENST00000322810 NM_201380.2 735 gaC/gaT 0 +PLEC UCSF GRCh37 8 145010027 145010027 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 21 46 0 ENST00000322810.4:c.1002C>T p.Ile334= p.I334= ENST00000322810 NM_201380.2 334 atC/atT 0 +PLEKHA5 UCSF GRCh37 12 19511364 19511364 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 20 70 0 ENST00000429027.2:c.3341C>T p.Thr1114Ile p.T1114I ENST00000429027 NM_001256470.1 1114 aCt/aTt 0 +PLEKHA6 UCSF GRCh37 1 204226627 204226627 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 15 0 ENST00000272203.3:c.1378C>T p.Pro460Ser p.P460S ENST00000272203 NM_014935.4 460 Ccc/Tcc 0 +PLEKHA6 UCSF GRCh37 1 204237376 204237376 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 30 24 60 0 ENST00000272203.3:c.167C>T p.Pro56Leu p.P56L ENST00000272203 NM_014935.4 56 cCc/cTc 0 +PLEKHG5 UCSF GRCh37 1 6531862 6531862 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 7 30 0 ENST00000537245.1:c.1324C>T p.Leu442= p.L442= ENST00000537245 NM_001265592.1 442 Ctg/Ttg 0 +PLEKHH1 UCSF GRCh37 14 68042659 68042659 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 58 141 0 ENST00000329153.5:c.2289C>T p.Thr763= p.T763= ENST00000329153 NM_020715.2 763 acC/acT 0 +PLEKHH1 UCSF GRCh37 14 68045917 68045917 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 44 60 0 ENST00000329153.5:c.2916G>A p.Glu972= p.E972= ENST00000329153 NM_020715.2 972 gaG/gaA 0 +PLEKHM2 UCSF GRCh37 1 16056318 16056318 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 86 150 0 ENST00000375799.3:c.2102C>T p.Ala701Val p.A701V ENST00000375799 NM_015164.2 701 gCc/gTc 0 +PLEKHO1 UCSF GRCh37 1 150131340 150131340 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 33 74 0 ENST00000369124.4:c.852C>T p.Ala284= p.A284= ENST00000369124 NM_016274.4 284 gcC/gcT 0 +PLIN3 UCSF GRCh37 19 4859655 4859655 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 41 65 1 ENST00000221957.4:c.295G>A p.Gly99Arg p.G99R ENST00000221957 NM_001164194.1 99 Ggg/Agg 0 +PLOD2 UCSF GRCh37 3 145828149 145828149 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 66 165 0 ENST00000282903.5:c.425G>A p.Gly142Glu p.G142E ENST00000282903 NM_182943.2 142 gGa/gAa 0 +PLVAP UCSF GRCh37 19 17476650 17476650 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 44 117 0 ENST00000252590.4:c.624C>T p.His208= p.H208= ENST00000252590 NM_031310.1 208 caC/caT 0 +PLXDC2 UCSF GRCh37 10 20506382 20506382 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 45 133 0 ENST00000377252.4:c.1150G>A p.Glu384Lys p.E384K ENST00000377252 NM_032812.7 384 Gaa/Aaa 0 +PLXNA1 UCSF GRCh37 3 126710278 126710278 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 11 40 0 ENST00000393409.2:c.1246G>A p.Gly416Arg p.G416R ENST00000393409 NM_032242.3 416 Ggg/Agg 0 +PLXNA3 UCSF GRCh37 X 153694768 153694768 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 44 99 0 ENST00000369682.3:c.2849G>A p.Gly950Asp p.G950D ENST00000369682 NM_017514.3 950 gGc/gAc 0 +PLXNB1 UCSF GRCh37 3 48459638 48459638 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 29 54 0 ENST00000358536.4:c.3184G>A p.Ala1062Thr p.A1062T ENST00000358536 NM_002673.4 1062 Gct/Act 0 +PLXNB3 UCSF GRCh37 X 153039127 153039127 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 21 22 28 0 ENST00000538966.1:c.3307G>A p.Asp1103Asn p.D1103N ENST00000538966 NM_001163257.1 1103 Gac/Aac 0 +PLXNB3 UCSF GRCh37 X 153041097 153041097 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 26 54 0 ENST00000538966.1:c.4452C>T p.Cys1484= p.C1484= ENST00000538966 NM_001163257.1 1484 tgC/tgT 0 +PLXND1 UCSF GRCh37 3 129279233 129279233 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 26 23 35 0 ENST00000324093.4:c.5073G>A p.Arg1691= p.R1691= ENST00000324093 NM_015103.2 1691 cgG/cgA 0 +PMF1 UCSF GRCh37 1 156203447 156203447 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 69 199 0 ENST00000368276.4:c.296G>A p.Gly99Glu p.G99E ENST00000368276 NM_001199661.1 99 gGg/gAg 0 +PMFBP1 UCSF GRCh37 16 72166782 72166782 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 84 155 0 ENST00000237353.10:c.1312G>A p.Ala438Thr p.A438T ENST00000237353 NM_031293.2 438 Gcc/Acc 0 +PML UCSF GRCh37 15 74315461 74315461 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 15 15 0 ENST00000268058.3:c.895G>A p.Glu299Lys p.E299K ENST00000268058 NM_033238.2 299 Gag/Aag 0 +PMM1 UCSF GRCh37 22 41973381 41973381 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 1 52 68 0 ENST00000216259.7:c.730C>T p.Gln244Ter p.Q244* ENST00000216259 NM_002676.2 244 Cag/Tag 0 +PMS1 UCSF GRCh37 2 190682849 190682849 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 39 95 0 ENST00000441310.2:c.525C>T p.Leu175= p.L175= ENST00000441310 NM_000534.4 175 ctC/ctT 0 +PNMA2 UCSF GRCh37 8 26366197 26366197 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 91 195 0 ENST00000522362.2:c.75G>A p.Gly25= p.G25= ENST00000522362 NM_007257.5 25 ggG/ggA 0 +PNO1 UCSF GRCh37 2 68385528 68385528 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 90 204 0 ENST00000263657.2:c.224C>T p.Thr75Ile p.T75I ENST00000263657 NM_020143.2 75 aCa/aTa 0 +PNP UCSF GRCh37 14 20943096 20943096 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 59 148 0 ENST00000361505.5:c.450C>T p.Pro150= p.P150= ENST00000361505 NM_000270.3 150 ccC/ccT 0 +PODXL2 UCSF GRCh37 3 127379246 127379246 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 61 161 0 ENST00000342480.6:c.375G>A p.Glu125= p.E125= ENST00000342480 NM_015720.3 125 gaG/gaA 0 +POLA1 UCSF GRCh37 X 24761422 24761422 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 77 170 0 ENST00000379059.3:c.2524G>A p.Gly842Ser p.G842S ENST00000379059 NM_016937.3 842 Ggc/Agc 0 +POLB UCSF GRCh37 8 42213081 42213081 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 60 93 0 ENST00000265421.4:c.418C>T p.Leu140= p.L140= ENST00000265421 NM_002690.2 140 Ctg/Ttg 0 +POLE UCSF GRCh37 12 133244177 133244177 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 124 91 193 0 ENST00000320574.5:c.2231C>T p.Thr744Ile p.T744I ENST00000320574 NM_006231.2 744 aCc/aTc 0 +POLN UCSF GRCh37 4 2083381 2083381 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 33 60 0 ENST00000511885.2:c.2287G>A p.Ala763Thr p.A763T ENST00000511885 763 Gca/Aca 0 +POLN UCSF GRCh37 4 2073858 2073858 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 30 112 0 ENST00000511885.2:c.2686C>T p.Pro896Ser p.P896S ENST00000511885 896 Cct/Tct 0 +POLN UCSF GRCh37 4 2209757 2209757 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 96 168 0 ENST00000511885.2:c.671C>T p.Thr224Ile p.T224I ENST00000511885 224 aCt/aTt 0 +POLQ UCSF GRCh37 3 121151764 121151764 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 79 217 0 ENST00000264233.5:c.7659+1G>A p.X2553_splice ENST00000264233 NM_199420.3 0 +POLR1D UCSF GRCh37 13 28239967 28239967 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 31 150 0 ENST00000399697.3:c.246C>T p.Asn82= p.N82= ENST00000399697 NM_152705.2 82 aaC/aaT 0 +POLR3A UCSF GRCh37 10 79767606 79767606 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 92 182 0 ENST00000372371.3:c.1928G>A p.Ser643Asn p.S643N ENST00000372371 NM_007055.3 643 aGt/aAt 0 +POLR3A UCSF GRCh37 10 79770278 79770278 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 74 104 0 ENST00000372371.3:c.1593C>T p.Thr531= p.T531= ENST00000372371 NM_007055.3 531 acC/acT 0 +POLRMT UCSF GRCh37 19 621684 621684 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 23 29 0 ENST00000588649.2:c.2014C>T p.Arg672Cys p.R672C ENST00000588649 NM_005035.3 672 Cgc/Tgc 0 +POLRMT UCSF GRCh37 19 622877 622877 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 9 31 0 ENST00000588649.2:c.1399C>T p.Leu467Phe p.L467F ENST00000588649 NM_005035.3 467 Ctt/Ttt 0 +POMT1 UCSF GRCh37 9 134385701 134385701 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 49 76 0 ENST00000372228.3:c.820G>A p.Val274Ile p.V274I ENST00000372228 NM_007171.3 274 Gtc/Atc 0 +POMT2 UCSF GRCh37 14 77786960 77786960 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 10 21 0 ENST00000261534.4:c.65G>A p.Gly22Asp p.G22D ENST00000261534 NM_013382.5 22 gGc/gAc 0 +PON3 UCSF GRCh37 7 95025659 95025659 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 41 90 0 ENST00000265627.5:c.4G>A p.Gly2Arg p.G2R ENST00000265627 NM_000940.2 2 Ggg/Agg 0 +POPDC2 UCSF GRCh37 3 119367215 119367215 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 53 75 0 ENST00000264231.3:c.901C>T p.Pro301Ser p.P301S ENST00000264231 NM_022135.2 301 Ccc/Tcc 0 +POT1 UCSF GRCh37 7 124510964 124510964 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 62 140 0 ENST00000357628.3:c.255+1G>A p.X85_splice ENST00000357628 NM_015450.2 0 +POU2F1 UCSF GRCh37 1 167381512 167381512 + synonymous_variant Silent SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 16 22 22 0 ENST00000367866.2:c.1872C>T p.Ser624= p.S624= ENST00000367866 NM_002697.3 624 agC/agT 0 +POU5F1B UCSF GRCh37 8 128428899 128428899 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 241 76 146 0 ENST00000465342.2:c.788C>T p.Ala263Val p.A263V ENST00000465342 263 gCc/gTc 0 +PPAPDC1B UCSF GRCh37 8 38125910 38125910 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 47 95 0 ENST00000424479.2:c.253G>A p.Asp85Asn p.D85N ENST00000424479 NM_001102559.1 85 Gac/Aac 0 +PPAPDC3 UCSF GRCh37 9 134165620 134165620 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 96 43 82 0 ENST00000372264.3:c.236G>A p.Gly79Asp p.G79D ENST00000372264 NM_032728.3 79 gGc/gAc 0 +PPFIA2 UCSF GRCh37 12 81768505 81768505 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 127 120 228 0 ENST00000549396.1:c.1174G>A p.Ala392Thr p.A392T ENST00000549396 NM_003625.3 392 Gct/Act 0 +PPFIA2 UCSF GRCh37 12 81657155 81657155 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 63 177 0 ENST00000549396.1:c.3570C>T p.Asn1190= p.N1190= ENST00000549396 NM_003625.3 1190 aaC/aaT 0 +PPFIBP2 UCSF GRCh37 11 7674408 7674408 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 1 43 94 0 ENST00000299492.4:c.2590C>T p.Pro864Ser p.P864S ENST00000299492 NM_003621.3 864 Cct/Tct 0 +PPIG UCSF GRCh37 2 170487383 170487383 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 64 147 0 ENST00000260970.3:c.647C>T p.Ser216Phe p.S216F ENST00000260970 NM_004792.2 216 tCc/tTc 0 +PPIP5K2 UCSF GRCh37 5 102491695 102491695 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 33 64 0 ENST00000321521.9:c.1486G>A p.Glu496Lys p.E496K ENST00000321521 496 Gag/Aag 0 +PPM1B UCSF GRCh37 2 44428804 44428804 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 89 168 0 ENST00000282412.4:c.466C>T p.Leu156= p.L156= ENST00000282412 NM_002706.4 156 Ctg/Ttg 0 +PPM1D UCSF GRCh37 17 58740364 58740364 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 59 139 0 ENST00000305921.3:c.1269G>A p.Glu423= p.E423= ENST00000305921 NM_003620.3 423 gaG/gaA 0 +PPM1F UCSF GRCh37 22 22277491 22277491 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 58 96 0 ENST00000263212.5:c.1339G>A p.Glu447Lys p.E447K ENST00000263212 NM_014634.3 447 Gag/Aag 0 +PPM1F UCSF GRCh37 22 22277695 22277695 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 28 62 0 ENST00000263212.5:c.1135C>T p.Leu379= p.L379= ENST00000263212 NM_014634.3 379 Ctg/Ttg 0 +PPP1R12A UCSF GRCh37 12 80222115 80222115 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 92 191 0 ENST00000450142.2:c.777G>A p.Glu259= p.E259= ENST00000450142 NM_002480.2 259 gaG/gaA 0 +PPP1R9A UCSF GRCh37 7 94913617 94913617 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 87 159 0 ENST00000433360.1:c.3584C>T p.Ser1195Phe p.S1195F ENST00000433360 NM_001166160.1 1195 tCt/tTt 0 +PPP2R1A UCSF GRCh37 19 52719110 52719110 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 55 137 0 ENST00000322088.6:c.886G>A p.Ala296Thr p.A296T ENST00000322088 NM_014225.5 296 Gcc/Acc 0 +PPP2R2D UCSF GRCh37 10 133747977 133747977 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 112 201 0 ENST00000455566.1:c.23C>T p.Thr8Ile p.T8I ENST00000455566 NM_018461.3 8 aCc/aTc 0 +PPP2R5B UCSF GRCh37 11 64698907 64698907 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 30 68 0 ENST00000164133.2:c.892-1G>A p.X298_splice ENST00000164133 NM_006244.3 0 +PPP4R1 UCSF GRCh37 18 9550361 9550361 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 68 178 0 ENST00000400556.3:c.2327G>A p.Arg776Lys p.R776K ENST00000400556 NM_001042388.2 776 aGa/aAa 0 +PPP5C UCSF GRCh37 19 46891687 46891687 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 19 54 0 ENST00000012443.4:c.1158G>A p.Trp386Ter p.W386* ENST00000012443 NM_006247.3 386 tgG/tgA 0 +PPP6C UCSF GRCh37 9 127923179 127923179 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 47 95 0 ENST00000373547.4:c.178G>A p.Asp60Asn p.D60N ENST00000373547 NM_002721.4 60 Gac/Aac 0 +PPPDE1 UCSF GRCh37 1 244852625 244852625 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 54 141 0 ENST00000302550.11:c.190G>A p.Gly64Arg p.G64R ENST00000302550 NM_016076.3 64 Gga/Aga 0 +PPRC1 UCSF GRCh37 10 103901077 103901078 + frameshift_variant Frame_Shift_Ins INS - - C NOVEL P10_Rec Untested WXS Illumina HiSeq 29 0 ENST00000278070.2:c.2819dup p.Pro941ThrfsTer75 p.P941Tfs*75 ENST00000278070 NM_015062.3 938 ccc/cCcc 0 +PPT1 UCSF GRCh37 1 40557012 40557012 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 28 69 0 ENST00000433473.3:c.422G>A p.Gly141Glu p.G141E ENST00000433473 NM_000310.3 141 gGa/gAa 0 +PPT1 UCSF GRCh37 1 40557775 40557775 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 68 139 0 ENST00000433473.3:c.304G>A p.Asp102Asn p.D102N ENST00000433473 NM_000310.3 102 Gat/Aat 0 +PQLC3 UCSF GRCh37 2 11312087 11312087 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 80 162 0 ENST00000295083.3:c.391G>A p.Ala131Thr p.A131T ENST00000295083 NM_152391.3 131 Gca/Aca 0 +PRAM1 UCSF GRCh37 19 8564207 8564207 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 34 65 0 ENST00000423345.4:c.485C>T p.Ala162Val p.A162V ENST00000423345 162 gCg/gTg 0 +PRB2 UCSF GRCh37 12 11546792 11546792 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 66 201 0 ENST00000389362.4:c.220C>T p.Pro74Ser p.P74S ENST00000389362 NM_006248.3 74 Cct/Tct 0 +PRB3 UCSF GRCh37 12 11421042 11421042 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 60 146 0 ENST00000381842.3:c.141C>T p.Pro47= p.P47= ENST00000381842 NM_006249.4 47 ccC/ccT 0 +PRDM10 UCSF GRCh37 11 129787087 129787087 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 41 113 0 ENST00000358825.5:c.2272G>A p.Val758Met p.V758M ENST00000358825 NM_020228.2 758 Gtg/Atg 0 +PRDM13 UCSF GRCh37 6 100061157 100061157 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 14 25 0 ENST00000369215.4:c.646C>T p.Pro216Ser p.P216S ENST00000369215 NM_021620.3 216 Cca/Tca 0 +PRDM15 UCSF GRCh37 21 43259799 43259799 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 85 195 0 ENST00000269844.3:c.1902G>A p.Arg634= p.R634= ENST00000269844 NM_022115.3 634 agG/agA 0 +PRDM2 UCSF GRCh37 1 14108749 14108749 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P10_Rec Untested WXS Illumina HiSeq 7 0 ENST00000235372.7:c.4467delA p.Val1490PhefsTer74 p.V1490Ffs*74 ENST00000235372 NM_012231.4 1487 Aaa/aa 0 +PRDX4 UCSF GRCh37 X 23697334 23697334 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 76 179 0 ENST00000379341.4:c.529C>T p.Leu177Phe p.L177F ENST00000379341 NM_006406.1 177 Ctt/Ttt 0 +PREP UCSF GRCh37 6 105736761 105736761 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 50 129 0 ENST00000369110.3:c.1326C>T p.Tyr442= p.Y442= ENST00000369110 NM_002726.4 442 taC/taT 0 +PREX1 UCSF GRCh37 20 47364366 47364366 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 21 53 0 ENST00000371941.3:c.271C>T p.Leu91Phe p.L91F ENST00000371941 NM_020820.3 91 Ctc/Ttc 0 +PREX1 UCSF GRCh37 20 47273622 47273622 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 14 30 0 ENST00000371941.3:c.2079C>T p.Cys693= p.C693= ENST00000371941 NM_020820.3 693 tgC/tgT 0 +PREX2 UCSF GRCh37 8 69104660 69104660 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 35 61 0 ENST00000288368.4:c.4504G>A p.Ala1502Thr p.A1502T ENST00000288368 NM_024870.2 1502 Gct/Act 0 +PRICKLE4 UCSF GRCh37 6 41752787 41752787 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 52 127 0 ENST00000458694.1:c.355C>T p.Leu119Phe p.L119F ENST00000458694 NM_013397.5 119 Ctt/Ttt 0 +PRKAR2A UCSF GRCh37 3 48789107 48789107 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 60 85 0 ENST00000265563.8:c.1126G>A p.Asp376Asn p.D376N ENST00000265563 NM_004157.2 376 Gac/Aac 0 +PRKCZ UCSF GRCh37 1 2105397 2105397 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 47 77 0 ENST00000378567.3:c.1347C>T p.Ser449= p.S449= ENST00000378567 NM_002744.4 449 tcC/tcT 0 +PRKD3 UCSF GRCh37 2 37480324 37480324 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 113 79 197 0 ENST00000379066.1:c.2669C>T p.Pro890Leu p.P890L ENST00000379066 890 cCt/cTt 0 +PRLHR UCSF GRCh37 10 120354365 120354365 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 28 32 0 ENST00000239032.2:c.392G>A p.Gly131Asp p.G131D ENST00000239032 NM_004248.2 131 gGc/gAc 0 +PRMT10 UCSF GRCh37 4 148575327 148575327 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 99 179 0 ENST00000322396.6:c.1721C>T p.Thr574Ile p.T574I ENST00000322396 NM_138364.2 574 aCt/aTt 0 +PRNP UCSF GRCh37 20 4680067 4680067 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 35 61 0 ENST00000379440.4:c.201G>A p.Gln67= p.Q67= ENST00000379440 NM_001080121.1 67 caG/caA 0 +PRODH2 UCSF GRCh37 19 36297377 36297377 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 46 109 0 ENST00000301175.3:c.1184G>A p.Gly395Glu p.G395E ENST00000301175 NM_021232.1 395 gGg/gAg 0 +PROL1 UCSF GRCh37 4 71275286 71275286 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 125 229 0 ENST00000399575.2:c.241G>A p.Ala81Thr p.A81T ENST00000399575 NM_021225.4 81 Gca/Aca 0 +PROX1 UCSF GRCh37 1 214170076 214170076 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 58 129 0 ENST00000366958.4:c.198G>A p.Lys66= p.K66= ENST00000366958 NM_001270616.1 66 aaG/aaA 0 +PRPF3 UCSF GRCh37 1 150316697 150316697 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 61 129 0 ENST00000324862.6:c.1486G>A p.Val496Ile p.V496I ENST00000324862 NM_004698.2 496 Gta/Ata 0 +PRPF40B UCSF GRCh37 12 50028958 50028958 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 36 89 0 ENST00000548825.2:c.1078G>A p.Glu360Lys p.E360K ENST00000548825 NM_001031698.2 360 Gag/Aag 0 +PRPF8 UCSF GRCh37 17 1554985 1554985 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 85 169 0 ENST00000572621.1:c.6467C>T p.Thr2156Ile p.T2156I ENST00000572621 2156 aCc/aTc 0 +PRR15 UCSF GRCh37 7 29606223 29606223 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 21 8 22 0 ENST00000319694.2:c.278G>A p.Arg93His p.R93H ENST00000319694 NM_175887.2 93 cGc/cAc 0 +PRR19 UCSF GRCh37 19 42814728 42814728 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 85 151 0 ENST00000499536.2:c.907G>A p.Val303Ile p.V303I ENST00000499536 303 Gtt/Att 0 +PRRC2A UCSF GRCh37 6 31600268 31600268 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 65 103 0 ENST00000376033.2:c.3818G>A p.Gly1273Asp p.G1273D ENST00000376033 NM_004638.3 1273 gGc/gAc 0 +PRRG3 UCSF GRCh37 X 150869246 150869246 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 53 95 0 ENST00000370353.3:c.437C>T p.Ser146Phe p.S146F ENST00000370353 146 tCt/tTt 0 +PRRT2 UCSF GRCh37 16 29825136 29825136 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 46 82 0 ENST00000567659.1:c.761C>T p.Pro254Leu p.P254L ENST00000567659 254 cCt/cTt 0 +PRRT2 UCSF GRCh37 16 29824583 29824583 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 44 97 0 ENST00000567659.1:c.208G>A p.Glu70Lys p.E70K ENST00000567659 70 Gaa/Aaa 0 +PRSS36 UCSF GRCh37 16 31150554 31150554 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 47 65 0 ENST00000268281.4:c.2473G>A p.Gly825Ser p.G825S ENST00000268281 NM_173502.4 825 Ggc/Agc 0 +PRSS36 UCSF GRCh37 16 31159864 31159864 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 16 16 26 0 ENST00000268281.4:c.405G>A p.Glu135= p.E135= ENST00000268281 NM_173502.4 135 gaG/gaA 0 +PRUNE2 UCSF GRCh37 9 79324065 79324065 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 241 137 213 0 ENST00000376718.3:c.3125C>T p.Ser1042Phe p.S1042F ENST00000376718 NM_015225.2 1042 tCt/tTt 0 +PSAT1 UCSF GRCh37 9 80919695 80919695 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 164 56 170 0 ENST00000376588.3:c.236G>A p.Gly79Glu p.G79E ENST00000376588 NM_058179.3 79 gGg/gAg 0 +PSMA3 UCSF GRCh37 14 58718883 58718883 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 63 163 0 ENST00000216455.4:c.151G>A p.Glu51Lys p.E51K ENST00000216455 NM_152132.2 51 Gaa/Aaa 0 +PSMB11 UCSF GRCh37 14 23511517 23511517 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 53 104 1 ENST00000408907.2:c.83C>T p.Ala28Val p.A28V ENST00000408907 NM_001099780.1 28 gCt/gTt 0 +PSMB5 UCSF GRCh37 14 23503905 23503905 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 24 52 0 ENST00000361611.6:c.186C>T p.Thr62= p.T62= ENST00000361611 NM_002797.3 62 acC/acT 0 +PSMB7 UCSF GRCh37 9 127167651 127167651 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 256 109 182 0 ENST00000259457.3:c.456C>T p.His152= p.H152= ENST00000259457 NM_002799.3 152 caC/caT 0 +PSMF1 UCSF GRCh37 20 1145035 1145035 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 99 185 1 ENST00000335877.6:c.679G>A p.Gly227Ser p.G227S ENST00000335877 NM_006814.3 227 Ggc/Agc 0 +PSTPIP1 UCSF GRCh37 15 77321869 77321869 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 9 29 0 ENST00000558012.1:c.517-1G>A p.X173_splice ENST00000558012 NM_003978.3 0 +PTBP2 UCSF GRCh37 1 97250756 97250756 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 68 127 0 ENST00000426398.2:c.850C>T p.Pro284Ser p.P284S ENST00000426398 NM_021190.2 284 Cct/Tct 0 +PTCHD3 UCSF GRCh37 10 27702675 27702675 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 155 63 148 0 ENST00000438700.3:c.505G>A p.Glu169Lys p.E169K ENST00000438700 NM_001034842.3 169 Gag/Aag 0 +PTGER4 UCSF GRCh37 5 40681248 40681248 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 73 113 0 ENST00000302472.3:c.153G>A p.Glu51= p.E51= ENST00000302472 NM_000958.2 51 gaG/gaA 0 +PTGFRN UCSF GRCh37 1 117504007 117504007 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 60 110 0 ENST00000393203.2:c.1356C>T p.Asn452= p.N452= ENST00000393203 NM_020440.2 452 aaC/aaT 0 +PTGR2 UCSF GRCh37 14 74343866 74343866 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 88 159 0 ENST00000555661.1:c.514G>A p.Gly172Arg p.G172R ENST00000555661 172 Ggg/Agg 0 +PTGS1 UCSF GRCh37 9 125148858 125148858 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 195 79 200 0 ENST00000362012.2:c.1143C>T p.Asn381= p.N381= ENST00000362012 NM_000962.3 381 aaC/aaT 0 +PTGS1 UCSF GRCh37 9 125145892 125145892 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 37 71 0 ENST00000362012.2:c.867G>A p.Glu289= p.E289= ENST00000362012 NM_000962.3 289 gaG/gaA 0 +PTGS1 UCSF GRCh37 9 125145946 125145946 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 43 85 0 ENST00000362012.2:c.921G>A p.Glu307= p.E307= ENST00000362012 NM_000962.3 307 gaG/gaA 0 +PTH2R UCSF GRCh37 2 209302275 209302275 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 32 35 90 0 ENST00000272847.2:c.192C>T p.Phe64= p.F64= ENST00000272847 NM_005048.3 64 ttC/ttT 0 +PTK2 UCSF GRCh37 8 141829029 141829043 + inframe_deletion In_Frame_Del DEL GGATCTCAAAGAATT GGATCTCAAAGAATT - NOVEL P10_Rec Untested WXS Illumina HiSeq 199 0 ENST00000340930.3:c.725_739del p.Lys242_Leu247delinsMet p.K242_L247delinsM ENST00000340930 NM_001199649.1 242 aAATTCTTTGAGATCCtg/atg 0 +PTK2B UCSF GRCh37 8 27315931 27315931 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 23 25 34 0 ENST00000397501.1:c.2935G>A p.Ala979Thr p.A979T ENST00000397501 NM_173174.2 979 Gct/Act 0 +PTK2B UCSF GRCh37 8 27296632 27296632 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0045 P10_Rec Untested WXS Illumina HiSeq 51 42 92 1 ENST00000397501.1:c.1728C>T p.Asp576= p.D576= ENST00000397501 NM_173174.2 576 gaC/gaT 0 +PTK6 UCSF GRCh37 20 62161534 62161534 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 44 71 0 ENST00000217185.2:c.1065C>T p.Ala355= p.A355= ENST00000217185 NM_005975.3 355 gcC/gcT 0 +PTPN13 UCSF GRCh37 4 87593580 87593580 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 47 134 0 ENST00000436978.1:c.178C>T p.Pro60Ser p.P60S ENST00000436978 NM_080685.2 60 Cca/Tca 0 +PTPN4 UCSF GRCh37 2 120702686 120702686 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 46 113 0 ENST00000263708.2:c.1385C>T p.Pro462Leu p.P462L ENST00000263708 NM_002830.3 462 cCt/cTt 0 +PTPN5 UCSF GRCh37 11 18755141 18755141 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 7 104 0 ENST00000358540.2:c.1042G>A p.Asp348Asn p.D348N ENST00000358540 NM_006906.1 348 Gac/Aac 0 +PTPN5 UCSF GRCh37 11 18764003 18764003 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 41 49 0 ENST00000358540.2:c.531C>T p.Pro177= p.P177= ENST00000358540 NM_006906.1 177 ccC/ccT 0 +PTPRA UCSF GRCh37 20 3008476 3008476 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 48 111 0 ENST00000380393.3:c.1909G>A p.Glu637Lys p.E637K ENST00000380393 NM_002836.3 637 Gag/Aag 0 +PTPRB UCSF GRCh37 12 70974815 70974815 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 61 167 0 ENST00000334414.6:c.2578+1G>A p.X860_splice ENST00000334414 NM_001109754.2 0 +PTPRC UCSF GRCh37 1 198725253 198725253 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 64 173 0 ENST00000442510.2:c.3864G>A p.Glu1288= p.E1288= ENST00000442510 1288 gaG/gaA 0 +PTPRCAP UCSF GRCh37 11 67203356 67203356 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 23 44 0 ENST00000326294.3:c.469G>A p.Gly157Ser p.G157S ENST00000326294 NM_005608.2 157 Ggc/Agc 0 +PTPRH UCSF GRCh37 19 55718105 55718105 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 68 186 0 ENST00000376350.3:c.304G>A p.Glu102Lys p.E102K ENST00000376350 NM_002842.3 102 Gag/Aag 0 +PTPRH UCSF GRCh37 19 55698945 55698945 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 64 135 0 ENST00000376350.3:c.2502G>A p.Gln834= p.Q834= ENST00000376350 NM_002842.3 834 caG/caA 0 +PTPRH UCSF GRCh37 19 55697841 55697841 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 47 142 0 ENST00000376350.3:c.2634C>T p.Ser878= p.S878= ENST00000376350 NM_002842.3 878 agC/agT 0 +PTPRK UCSF GRCh37 6 128399998 128399998 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 52 137 0 ENST00000368213.5:c.1843G>A p.Val615Ile p.V615I ENST00000368213 NM_001135648.1 615 Gta/Ata 0 +PTPRK UCSF GRCh37 6 128306890 128306890 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 55 135 0 ENST00000368213.5:c.3245C>T p.Ala1082Val p.A1082V ENST00000368213 NM_001135648.1 1082 gCt/gTt 0 +PTPRM UCSF GRCh37 18 7888373 7888373 + stop_gained,splice_region_variant Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 66 146 0 ENST00000580170.1:c.466C>T p.Gln156Ter p.Q156* ENST00000580170 NM_001105244.1 156 Cag/Tag 0 +PTPRM UCSF GRCh37 18 8394570 8394570 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 47 100 0 ENST00000580170.1:c.4305G>A p.Lys1435= p.K1435= ENST00000580170 NM_001105244.1 1435 aaG/aaA 0 +PTPRU UCSF GRCh37 1 29605526 29605526 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 11 24 0 ENST00000345512.3:c.1456C>T p.Pro486Ser p.P486S ENST00000345512 NM_005704.4 486 Ccc/Tcc 0 +PTPRU UCSF GRCh37 1 29609209 29609209 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 21 40 0 ENST00000345512.3:c.1890G>A p.Glu630= p.E630= ENST00000345512 NM_005704.4 630 gaG/gaA 0 +PTPRZ1 UCSF GRCh37 7 121680878 121680878 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 39 78 0 ENST00000393386.2:c.5646G>A p.Gln1882= p.Q1882= ENST00000393386 NM_001206838.1 1882 caG/caA 0 +PUF60 UCSF GRCh37 8 144900217 144900217 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 167 32 95 0 ENST00000526683.1:c.632C>T p.Ala211Val p.A211V ENST00000526683 NM_001271098.1 211 gCc/gTc 0 +PURA UCSF GRCh37 5 139494246 139494246 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 23 42 0 ENST00000331327.3:c.480G>A p.Lys160= p.K160= ENST00000331327 NM_005859.4 160 aaG/aaA 0 +PUS7L UCSF GRCh37 12 44149022 44149022 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 61 114 0 ENST00000416848.2:c.27C>T p.Ile9= p.I9= ENST00000416848 NM_001098615.1 9 atC/atT 0 +PVRL1 UCSF GRCh37 11 119549413 119549413 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 20 32 0 ENST00000264025.3:c.142G>A p.Val48Ile p.V48I ENST00000264025 NM_002855.4 48 Gtt/Att 0 +PVRL2 UCSF GRCh37 19 45389422 45389422 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 44 83 0 ENST00000252483.5:c.1293G>A p.Glu431= p.E431= ENST00000252483 NM_001042724.1 431 gaG/gaA 0 +PWP2 UCSF GRCh37 21 45534566 45534566 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 47 95 0 ENST00000291576.7:c.387G>A p.Arg129= p.R129= ENST00000291576 NM_005049.2 129 cgG/cgA 0 +PWWP2A UCSF GRCh37 5 159520808 159520808 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 124 111 237 0 ENST00000307063.7:c.849C>T p.Asn283= p.N283= ENST00000307063 NM_001130864.1 283 aaC/aaT 0 +QRFPR UCSF GRCh37 4 122254126 122254126 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 45 144 0 ENST00000394427.2:c.647C>T p.Thr216Ile p.T216I ENST00000394427 NM_198179.2 216 aCc/aTc 0 +R3HCC1 UCSF GRCh37 8 23146530 23146530 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 52 145 0 ENST00000265806.6:c.-450G>A p.X150_splice ENST00000265806 NM_001136108.1 0 +R3HDM1 UCSF GRCh37 2 136403068 136403068 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 78 187 0 ENST00000264160.4:c.1594C>T p.Gln532Ter p.Q532* ENST00000264160 NM_015361.2 532 Caa/Taa 0 +R3HDM2 UCSF GRCh37 12 57696963 57696963 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 52 116 0 ENST00000347140.3:c.203C>T p.Ala68Val p.A68V ENST00000347140 68 gCc/gTc 0 +RAB2B UCSF GRCh37 14 21936563 21936563 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 29 80 0 ENST00000397762.1:c.315G>A p.Arg105= p.R105= ENST00000397762 NM_032846.3 105 cgG/cgA 0 +RAB40B UCSF GRCh37 17 80616416 80616416 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 61 123 0 ENST00000571995.1:c.516G>A p.Arg172= p.R172= ENST00000571995 NM_006822.2 172 agG/agA 0 +RABGGTB UCSF GRCh37 1 76253239 76253239 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 51 151 0 ENST00000319942.3:c.61G>A p.Glu21Lys p.E21K ENST00000319942 NM_004582.3 21 Gag/Aag 0 +RABL2B UCSF GRCh37 22 51208342 51208342 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 1 32 104 0 ENST00000395593.3:c.400A>G p.Lys134Glu p.K134E ENST00000395593 NM_001130923.1 134 Aaa/Gaa 0 +RAC3 UCSF GRCh37 17 79991357 79991357 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 18 41 0 ENST00000306897.4:c.330C>T p.Ile110= p.I110= ENST00000306897 NM_005052.2 110 atC/atT 0 +RACGAP1 UCSF GRCh37 12 50393516 50393516 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 50 128 0 ENST00000434422.1:c.631G>A p.Gly211Arg p.G211R ENST00000434422 211 Ggg/Agg 0 +RAD1 UCSF GRCh37 5 34911848 34911848 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 97 189 0 ENST00000382038.2:c.377G>A p.Gly126Glu p.G126E ENST00000382038 NM_002853.3 126 gGa/gAa 0 +RAD18 UCSF GRCh37 3 9000665 9000665 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 67 139 0 ENST00000264926.2:c.72G>A p.Arg24= p.R24= ENST00000264926 NM_020165.3 24 cgG/cgA 0 +RAD21 UCSF GRCh37 8 117868523 117868532 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACCCACTGTA ACCCACTGTA CCCCCCTGT NOVEL P10_Rec Untested WXS Illumina HiSeq 6 0 ENST00000297338.2:c.815-5_819delinsACAGGGGGG p.X272_splice ENST00000297338 NM_006265.2 0 +RAD51 UCSF GRCh37 15 41023350 41023350 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 65 143 0 ENST00000267868.3:c.994G>A p.Asp332Asn p.D332N ENST00000267868 NM_002875.4 332 Gat/Aat 0 +RAD51C UCSF GRCh37 17 56772316 56772316 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 99 210 0 ENST00000337432.4:c.170C>T p.Ala57Val p.A57V ENST00000337432 NM_058216.2 57 gCc/gTc 0 +RAD52 UCSF GRCh37 12 1040430 1040430 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 53 119 0 ENST00000358495.3:c.142G>A p.Gly48Ser p.G48S ENST00000358495 NM_134424.2 48 Ggc/Agc 0 +RAD54B UCSF GRCh37 8 95412584 95412584 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 126 43 110 0 ENST00000336148.5:c.1052G>A p.Gly351Asp p.G351D ENST00000336148 NM_012415.3 351 gGc/gAc 0 +RAD54B UCSF GRCh37 8 95479653 95479653 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 296 92 177 0 ENST00000336148.5:c.115C>T p.Pro39Ser p.P39S ENST00000336148 NM_012415.3 39 Cca/Tca 0 +RALGAPA2 UCSF GRCh37 20 20585937 20585937 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 140 125 227 0 ENST00000202677.7:c.1920G>A p.Trp640Ter p.W640* ENST00000202677 NM_020343.3 640 tgG/tgA 0 +RALGAPA2 UCSF GRCh37 20 20505167 20505167 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 67 152 0 ENST00000202677.7:c.3783C>T p.Leu1261= p.L1261= ENST00000202677 NM_020343.3 1261 ctC/ctT 0 +RALGPS1 UCSF GRCh37 9 129961336 129961336 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 142 77 135 0 ENST00000259351.5:c.1238G>A p.Gly413Glu p.G413E ENST00000259351 NM_014636.2 413 gGg/gAg 0 +RANBP17 UCSF GRCh37 5 170343577 170343577 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 81 166 0 ENST00000523189.1:c.943G>A p.Glu315Lys p.E315K ENST00000523189 NM_022897.3 315 Gaa/Aaa 0 +RANBP17 UCSF GRCh37 5 170669776 170669776 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 101 214 0 ENST00000523189.1:c.2728G>A p.Val910Ile p.V910I ENST00000523189 NM_022897.3 910 Gta/Ata 0 +RANBP2 UCSF GRCh37 2 109384589 109384589 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 201 167 293 0 ENST00000283195.6:c.7594C>T p.Pro2532Ser p.P2532S ENST00000283195 NM_006267.4 2532 Cca/Tca 0 +RANBP6 UCSF GRCh37 9 6014933 6014933 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 98 202 0 ENST00000259569.5:c.675G>A p.Leu225= p.L225= ENST00000259569 NM_012416.3 225 ttG/ttA 0 +RANBP9 UCSF GRCh37 6 13711180 13711180 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 3 16 0 ENST00000011619.3:c.558G>A p.Arg186= p.R186= ENST00000011619 NM_005493.2 186 cgG/cgA 0 +RAP1A UCSF GRCh37 1 112240111 112240111 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 61 144 0 ENST00000369709.3:c.175G>A p.Ala59Thr p.A59T ENST00000369709 NM_002884.2 59 Gca/Aca 0 +RAP1GAP UCSF GRCh37 1 21938289 21938289 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 55 138 0 ENST00000290101.4:c.825C>T p.Phe275= p.F275= ENST00000290101 NM_001145658.1 275 ttC/ttT 0 +RAPGEF6 UCSF GRCh37 5 130808360 130808360 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 41 121 0 ENST00000296859.6:c.2159C>T p.Pro720Leu p.P720L ENST00000296859 720 cCc/cTc 0 +RAPGEF6 UCSF GRCh37 5 130831301 130831301 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 44 115 0 ENST00000296859.6:c.1472G>A p.Gly491Asp p.G491D ENST00000296859 491 gGt/gAt 0 +RAPH1 UCSF GRCh37 2 204309628 204309628 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 61 171 2 ENST00000319170.5:c.1739C>T p.Ala580Val p.A580V ENST00000319170 NM_213589.1 580 gCc/gTc 0 +RASA3 UCSF GRCh37 13 114786977 114786977 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 22 67 0 ENST00000334062.7:c.688C>T p.Leu230Phe p.L230F ENST00000334062 NM_007368.2 230 Ctc/Ttc 0 +RASA3 UCSF GRCh37 13 114751087 114751087 + stop_gained,splice_region_variant Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 50 130 0 ENST00000334062.7:c.2428C>T p.Gln810Ter p.Q810* ENST00000334062 NM_007368.2 810 Cag/Tag 0 +RASGEF1C UCSF GRCh37 5 179554648 179554648 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 15 38 0 ENST00000393371.2:c.675C>T p.Val225= p.V225= ENST00000393371 225 gtC/gtT 0 +RASGRF2 UCSF GRCh37 5 80369113 80369113 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 66 200 0 ENST00000265080.4:c.729G>A p.Lys243= p.K243= ENST00000265080 NM_006909.2 243 aaG/aaA 0 +RASGRP4 UCSF GRCh37 19 38905542 38905542 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 21 33 0 ENST00000587738.1:c.1176C>T p.Leu392= p.L392= ENST00000587738 392 ctC/ctT 0 +RASSF2 UCSF GRCh37 20 4766911 4766911 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 89 201 0 ENST00000379400.3:c.877G>A p.Glu293Lys p.E293K ENST00000379400 NM_014737.2 293 Gaa/Aaa 0 +RBCK1 UCSF GRCh37 20 409726 409726 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 16 37 0 ENST00000356286.5:c.1440C>T p.Arg480= p.R480= ENST00000356286 NM_031229.2 480 cgC/cgT 0 +RBFA UCSF GRCh37 18 77794524 77794524 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 14 9 0 ENST00000306735.5:c.29G>A p.Arg10His p.R10H ENST00000306735 NM_024805.2 10 cGc/cAc 0 +RBKS UCSF GRCh37 2 28050538 28050538 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 46 89 0 ENST00000302188.3:c.691G>A p.Val231Met p.V231M ENST00000302188 NM_022128.1 231 Gtg/Atg 0 +RBL1 UCSF GRCh37 20 35632224 35632224 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 63 127 0 ENST00000373664.3:c.2917C>T p.Pro973Ser p.P973S ENST00000373664 NM_002895.3 973 Cca/Tca 0 +RBL1 UCSF GRCh37 20 35717525 35717525 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 105 74 154 0 ENST00000373664.3:c.157G>A p.Gly53Arg p.G53R ENST00000373664 NM_002895.3 53 Gga/Aga 0 +RBM10 UCSF GRCh37 X 47041020 47041020 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 22 48 0 ENST00000329236.7:c.1316G>A p.Ser439Asn p.S439N ENST00000329236 NM_001204466.1 439 aGc/aAc 0 +RBM12B UCSF GRCh37 8 94746508 94746508 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 225 87 157 0 ENST00000399300.2:c.2131C>T p.Pro711Ser p.P711S ENST00000399300 NM_203390.2 711 Cct/Tct 0 +RBM14 UCSF GRCh37 11 66391790 66391790 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 70 116 0 ENST00000310137.4:c.443C>T p.Thr148Ile p.T148I ENST00000310137 NM_006328.3 148 aCc/aTc 0 +RBM20 UCSF GRCh37 10 112581121 112581121 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 53 127 0 ENST00000369519.3:c.2744G>A p.Gly915Glu p.G915E ENST00000369519 NM_001134363.1 915 gGg/gAg 0 +RBM25 UCSF GRCh37 14 73544137 73544137 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 54 110 0 ENST00000261973.7:c.217G>A p.Gly73Ser p.G73S ENST00000261973 NM_021239.2 73 Ggc/Agc 0 +RBM33 UCSF GRCh37 7 155530819 155530819 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 111 127 194 0 ENST00000401878.3:c.1459C>T p.Pro487Ser p.P487S ENST00000401878 NM_053043.2 487 Ccg/Tcg 0 +RBM45 UCSF GRCh37 2 178988377 178988377 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 62 143 0 ENST00000286070.5:c.982G>A p.Asp328Asn p.D328N ENST00000286070 NM_152945.2 328 Gat/Aat 0 +RBMXL3 UCSF GRCh37 X 114425911 114425911 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 33 33 88 0 ENST00000424776.3:c.1907G>A p.Arg636His p.R636H ENST00000424776 NM_001145346.1 636 cGc/cAc 0 +RC3H2 UCSF GRCh37 9 125616365 125616365 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 236 98 179 0 ENST00000373670.1:c.2983G>A p.Ala995Thr p.A995T ENST00000373670 995 Gcc/Acc 0 +RCAN3 UCSF GRCh37 1 24859647 24859647 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 32 103 0 ENST00000374395.4:c.444C>T p.Ser148= p.S148= ENST00000374395 NM_001251984.1 148 tcC/tcT 0 +RECQL4 UCSF GRCh37 8 145740731 145740731 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 166 36 67 0 ENST00000428558.2:c.1369G>A p.Gly457Arg p.G457R ENST00000428558 NM_004260.3 457 Ggg/Agg 0 +RECQL4 UCSF GRCh37 8 145741398 145741398 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 250 44 96 0 ENST00000428558.2:c.1105C>T p.Leu369Phe p.L369F ENST00000428558 NM_004260.3 369 Ctc/Ttc 0 +RECQL5 UCSF GRCh37 17 73625500 73625500 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 35 69 0 ENST00000317905.5:c.2003C>T p.Thr668Met p.T668M ENST00000317905 NM_004259.6 668 aCg/aTg 0 +REEP6 UCSF GRCh37 19 1496425 1496425 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 23 55 0 ENST00000233596.3:c.490G>A p.Asp164Asn p.D164N ENST00000233596 NM_138393.1 164 Gac/Aac 0 +RELN UCSF GRCh37 7 103363610 103363610 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 32 103 0 ENST00000428762.1:c.782C>T p.Ala261Val p.A261V ENST00000428762 NM_005045.3 261 gCt/gTt 0 +RENBP UCSF GRCh37 X 153209422 153209422 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 21 27 0 ENST00000393700.3:c.214G>A p.Val72Ile p.V72I ENST00000393700 NM_002910.5 72 Gta/Ata 0 +REST UCSF GRCh37 4 57798062 57798062 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 67 135 0 ENST00000309042.7:c.3038G>A p.Ser1013Asn p.S1013N ENST00000309042 NM_005612.4 1013 aGc/aAc 0 +RET UCSF GRCh37 10 43597907 43597907 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 41 106 0 ENST00000355710.3:c.455C>T p.Thr152Ile p.T152I ENST00000355710 NM_020975.4 152 aCc/aTc 0 +REXO4 UCSF GRCh37 9 136282832 136282832 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 194 106 180 0 ENST00000371942.3:c.133G>A p.Val45Ile p.V45I ENST00000371942 NM_001279350.1 45 Gta/Ata 0 +RFC5 UCSF GRCh37 12 118464746 118464746 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 84 171 0 ENST00000454402.2:c.716C>T p.Thr239Ile p.T239I ENST00000454402 NM_007370.5 239 aCc/aTc 0 +RFNG UCSF GRCh37 17 80007572 80007572 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 11 14 0 ENST00000310496.4:c.809C>T p.Pro270Leu p.P270L ENST00000310496 NM_002917.1 270 cCc/cTc 0 +RFTN1 UCSF GRCh37 3 16411748 16411748 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 8 102 258 0 ENST00000334133.4:c.865C>T p.His289Tyr p.H289Y ENST00000334133 NM_015150.1 289 Cat/Tat 0 +RFWD2 UCSF GRCh37 1 176012861 176012861 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 67 185 0 ENST00000367669.3:c.1515G>A p.Arg505= p.R505= ENST00000367669 NM_022457.5 505 agG/agA 0 +RFX7 UCSF GRCh37 15 56471467 56471467 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 18 8 45 0 ENST00000423270.1:c.195+1G>A p.X65_splice ENST00000423270 NM_022841.5 0 +RFX7 UCSF GRCh37 15 56435014 56435014 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 120 180 0 ENST00000423270.1:c.363G>A p.Glu121= p.E121= ENST00000423270 NM_022841.5 121 gaG/gaA 0 +RGL3 UCSF GRCh37 19 11516053 11516053 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 22 28 0 ENST00000393423.3:c.1046C>T p.Ala349Val p.A349V ENST00000393423 349 gCc/gTc 0 +RGS4 UCSF GRCh37 1 163044336 163044336 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 86 163 1 ENST00000421743.2:c.895C>T p.Pro299Ser p.P299S ENST00000421743 NM_001102445.2 299 Cct/Tct 0 +RGS8 UCSF GRCh37 1 182617280 182617280 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 136 113 203 0 ENST00000258302.4:c.406C>T p.Pro136Ser p.P136S ENST00000258302 NM_033345.2 136 Cca/Tca 0 +RHPN1 UCSF GRCh37 8 144458815 144458815 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 11 20 0 ENST00000289013.6:c.297G>A p.Arg99= p.R99= ENST00000289013 NM_052924.2 99 cgG/cgA 0 +RHPN1 UCSF GRCh37 8 144460928 144460928 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 30 29 0 ENST00000289013.6:c.522G>A p.Gln174= p.Q174= ENST00000289013 NM_052924.2 174 caG/caA 0 +RIMBP3 UCSF GRCh37 22 20457152 20457152 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 150 70 207 0 ENST00000426804.1:c.4150G>A p.Glu1384Lys p.E1384K ENST00000426804 NM_015672.1 1384 Gag/Aag 0 +RING1 UCSF GRCh37 6 33177691 33177691 + splice_acceptor_variant Splice_Site SNP G G T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 35 101 0 ENST00000374656.4:c.240-1G>T p.X80_splice ENST00000374656 NM_002931.3 0 +RIOK3 UCSF GRCh37 18 21059389 21059389 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 32 98 0 ENST00000339486.3:c.1452+1G>A p.X484_splice ENST00000339486 NM_003831.3 0 +RIPK3 UCSF GRCh37 14 24805454 24805454 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 56 141 0 ENST00000216274.5:c.1484G>A p.Gly495Asp p.G495D ENST00000216274 NM_006871.3 495 gGt/gAt 0 +RIPK4 UCSF GRCh37 21 43169343 43169343 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 41 128 0 ENST00000332512.3:c.644G>A p.Gly215Asp p.G215D ENST00000332512 NM_020639.2 215 gGc/gAc 0 +RIPPLY1 UCSF GRCh37 X 106146371 106146371 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 49 102 0 ENST00000276173.4:c.147G>A p.Gly49= p.G49= ENST00000276173 NM_138382.2 49 ggG/ggA 0 +RIPPLY1 UCSF GRCh37 X 106146449 106146449 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 39 103 0 ENST00000276173.4:c.69C>T p.Asp23= p.D23= ENST00000276173 NM_138382.2 23 gaC/gaT 0 +RIT1 UCSF GRCh37 1 155874248 155874248 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 57 113 0 ENST00000368323.3:c.283G>A p.Gly95Arg p.G95R ENST00000368323 NM_006912.5 95 Ggg/Agg 0 +RLF UCSF GRCh37 1 40704129 40704129 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 74 166 0 ENST00000372771.4:c.3755G>A p.Ser1252Asn p.S1252N ENST00000372771 NM_012421.3 1252 aGt/aAt 0 +RMI1 UCSF GRCh37 9 86617645 86617645 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 179 90 170 0 ENST00000325875.3:c.1744C>T p.Gln582Ter p.Q582* ENST00000325875 NM_024945.2 582 Caa/Taa 0 +RNASE1 UCSF GRCh37 14 21269809 21269809 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 72 132 0 ENST00000397967.4:c.419G>A p.Gly140Glu p.G140E ENST00000397967 NM_002933.4 140 gGg/gAg 0 +RNASEL UCSF GRCh37 1 182551378 182551378 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 69 165 0 ENST00000367559.3:c.1582G>A p.Val528Ile p.V528I ENST00000367559 NM_021133.3 528 Gtc/Atc 0 +RNF11 UCSF GRCh37 1 51702498 51702498 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 20 53 0 ENST00000242719.3:c.70G>A p.Ala24Thr p.A24T ENST00000242719 NM_014372.4 24 Gct/Act 0 +RNF19A UCSF GRCh37 8 101281054 101281054 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 185 60 142 0 ENST00000519449.1:c.1150C>T p.Pro384Ser p.P384S ENST00000519449 NM_015435.4 384 Cct/Tct 0 +RNF208 UCSF GRCh37 9 140115417 140115417 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 4 17 0 ENST00000392827.1:c.248C>T p.Pro83Leu p.P83L ENST00000392827 83 cCt/cTt 0 +RNF213 UCSF GRCh37 17 78318527 78318527 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 95 197 0 ENST00000582970.1:c.6392C>T p.Thr2131Ile p.T2131I ENST00000582970 NM_001256071.1 2131 aCc/aTc 0 +RNF217 UCSF GRCh37 6 125398004 125398004 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 72 162 0 ENST00000359704.2:c.607G>A p.Ala203Thr p.A203T ENST00000359704 NM_152553.2 203 Gct/Act 0 +RNF31 UCSF GRCh37 14 24618685 24618685 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 54 130 0 ENST00000324103.6:c.702G>A p.Gln234= p.Q234= ENST00000324103 NM_017999.4 234 caG/caA 0 +RNF38 UCSF GRCh37 9 36390546 36390546 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 295 97 186 0 ENST00000259605.6:c.80G>A p.Arg27Lys p.R27K ENST00000259605 NM_022781.4 27 aGa/aAa 0 +RNF40 UCSF GRCh37 16 30780214 30780214 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 53 116 0 ENST00000324685.6:c.2153G>A p.Ser718Asn p.S718N ENST00000324685 NM_014771.3 718 aGc/aAc 0 +RNF43 UCSF GRCh37 17 56436066 56436066 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 5 10 0 ENST00000407977.2:c.1071C>T p.Tyr357= p.Y357= ENST00000407977 357 taC/taT 0 +ROBO3 UCSF GRCh37 11 124747872 124747872 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 19 55 0 ENST00000397801.1:c.3026G>A p.Gly1009Asp p.G1009D ENST00000397801 NM_022370.3 1009 gGc/gAc 0 +RORA UCSF GRCh37 15 60803566 60803566 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 77 161 0 ENST00000261523.5:c.778C>T p.Pro260Ser p.P260S ENST00000261523 NM_134260.2 260 Cct/Tct 0 +RP1 UCSF GRCh37 8 55537248 55537248 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 64 172 0 ENST00000220676.1:c.806C>T p.Ser269Leu p.S269L ENST00000220676 NM_006269.1 269 tCa/tTa 0 +RP1 UCSF GRCh37 8 55539071 55539071 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 72 128 0 ENST00000220676.1:c.2629G>A p.Val877Met p.V877M ENST00000220676 NM_006269.1 877 Gtg/Atg 0 +RP2 UCSF GRCh37 X 46713551 46713551 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 61 132 0 ENST00000218340.3:c.743C>T p.Ala248Val p.A248V ENST00000218340 NM_006915.2 248 gCa/gTa 0 +RPA1 UCSF GRCh37 17 1775757 1775757 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 24 42 0 ENST00000254719.5:c.391G>A p.Ala131Thr p.A131T ENST00000254719 NM_002945.3 131 Gcg/Acg 0 +RPAP1 UCSF GRCh37 15 41813134 41813134 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 41 58 0 ENST00000304330.4:c.3250G>A p.Val1084Ile p.V1084I ENST00000304330 NM_015540.2 1084 Gtc/Atc 0 +RPE UCSF GRCh37 2 210880814 210880814 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 55 57 138 0 ENST00000359429.6:c.320A>G p.Asp107Gly p.D107G ENST00000359429 NM_199229.2 107 gAc/gGc 0 +RPGRIP1L UCSF GRCh37 16 53692758 53692758 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 34 32 82 0 ENST00000379925.3:c.1276G>A p.Glu426Lys p.E426K ENST00000379925 NM_015272.2 426 Gaa/Aaa 0 +RPL18 UCSF GRCh37 19 49119203 49119203 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 22 49 0 ENST00000549920.1:c.422G>A p.Gly141Asp p.G141D ENST00000549920 NM_000979.3 141 gGt/gAt 0 +RPL23 UCSF GRCh37 17 37006395 37006395 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 44 105 0 ENST00000479035.2:c.413G>A p.Ser138Asn p.S138N ENST00000479035 NM_000978.3 138 aGc/aAc 0 +RPL8 UCSF GRCh37 8 146016857 146016857 + missense_variant Missense_Mutation SNP G G A snp132_rs11539887 P10_Rec somatic WXS Sanger Illumina HiSeq 120 29 60 0 ENST00000262584.3:c.304C>T p.Leu102Phe p.L102F ENST00000262584 NM_000973.3 102 Ctc/Ttc 0 +RPL8 UCSF GRCh37 8 146016729 146016729 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 179 37 83 0 ENST00000262584.3:c.432G>A p.Lys144= p.K144= ENST00000262584 NM_000973.3 144 aaG/aaA 0 +RPS2 UCSF GRCh37 16 2012774 2012774 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 29 63 0 ENST00000343262.4:c.512G>A p.Gly171Glu p.G171E ENST00000343262 NM_002952.3 171 gGg/gAg 0 +RQCD1 UCSF GRCh37 2 219458860 219458860 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 50 129 0 ENST00000273064.6:c.761C>T p.Pro254Leu p.P254L ENST00000273064 NM_005444.2 254 cCt/cTt 0 +RRBP1 UCSF GRCh37 20 17594837 17594837 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 40 107 0 ENST00000377807.2:c.2924C>T p.Thr975Ile p.T975I ENST00000377807 NM_001042576.1 975 aCc/aTc 0 +RRN3 UCSF GRCh37 16 15188002 15188002 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 11 23 0 ENST00000198767.6:c.89G>A p.Gly30Glu p.G30E ENST00000198767 NM_018427.3 30 gGg/gAg 0 +RRP1 UCSF GRCh37 21 45212611 45212611 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 63 139 0 ENST00000497547.1:c.274+1G>A p.X92_splice ENST00000497547 NM_003683.5 0 +RRP15 UCSF GRCh37 1 218480886 218480886 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 41 124 0 ENST00000366932.3:c.617C>T p.Ser206Phe p.S206F ENST00000366932 NM_016052.3 206 tCc/tTc 0 +RSAD1 UCSF GRCh37 17 48562189 48562189 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 35 47 0 ENST00000258955.2:c.1296G>A p.Gln432= p.Q432= ENST00000258955 NM_018346.1 432 caG/caA 0 +RSG1 UCSF GRCh37 1 16558551 16558551 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 46 91 0 ENST00000375599.3:c.769C>T p.Pro257Ser p.P257S ENST00000375599 NM_030907.3 257 Cct/Tct 0 +RSPO1 UCSF GRCh37 1 38095290 38095290 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 29 49 0 ENST00000356545.2:c.44C>T p.Thr15Met p.T15M ENST00000356545 NM_001038633.3 15 aCg/aTg 0 +RSPO2 UCSF GRCh37 8 109001403 109001403 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 206 69 156 0 ENST00000276659.5:c.164G>A p.Cys55Tyr p.C55Y ENST00000276659 NM_178565.4 55 tGt/tAt 0 +RTN4 UCSF GRCh37 2 55252930 55252930 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 73 182 0 ENST00000337526.6:c.2305G>A p.Glu769Lys p.E769K ENST00000337526 NM_020532.4 769 Gaa/Aaa 0 +RTP1 UCSF GRCh37 3 186917483 186917483 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 35 76 0 ENST00000312295.4:c.417G>A p.Arg139= p.R139= ENST00000312295 NM_153708.2 139 cgG/cgA 0 +RTTN UCSF GRCh37 18 67781812 67781812 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 73 182 0 ENST00000255674.6:c.3552C>T p.Leu1184= p.L1184= ENST00000255674 NM_173630.3 1184 ctC/ctT 0 +RUFY3 UCSF GRCh37 4 71634350 71634350 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 91 187 1 ENST00000381006.3:c.668G>A p.Cys223Tyr p.C223Y ENST00000381006 NM_001037442.2 223 tGt/tAt 0 +RUSC2 UCSF GRCh37 9 35547678 35547678 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 104 166 0 ENST00000455600.1:c.1160C>T p.Ala387Val p.A387V ENST00000455600 NM_001135999.1 387 gCc/gTc 0 +RWDD1 UCSF GRCh37 6 116914127 116914161 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TGGTTGCCTTTTGCAGCTGGAAACAACGTGGAGGT TGGTTGCCTTTTGCAGCTGGAAACAACGTGGAGGT GGTTGCCTTTTGCAGCTGGAAAAAACGGGGGGGG NOVEL P10_Rec Untested WXS Illumina HiSeq 6 0 ENST00000466444.2:c.611-16_629delinsGGTTGCCTTTTGCAGCTGGAAAAAACGGGGGGGG p.X204_splice ENST00000466444 NM_015952.2 0 +RXFP3 UCSF GRCh37 5 33937149 33937149 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 53 90 0 ENST00000330120.3:c.304G>A p.Val102Ile p.V102I ENST00000330120 NM_016568.3 102 Gtt/Att 0 +RXRG UCSF GRCh37 1 165386444 165386444 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 43 150 0 ENST00000359842.5:c.456G>A p.Gly152= p.G152= ENST00000359842 NM_001256570.1 152 ggG/ggA 0 +RYK UCSF GRCh37 3 133941301 133941301 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 50 120 0 ENST00000296084.4:c.309G>A p.Glu103= p.E103= ENST00000296084 NM_001005861.2 103 gaG/gaA 0 +RYR1 UCSF GRCh37 19 38980901 38980901 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 42 39 69 0 ENST00000359596.3:c.6000C>T p.Ser2000= p.S2000= ENST00000359596 2000 tcC/tcT 0 +RYR2 UCSF GRCh37 1 237837510 237837510 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 98 82 181 0 ENST00000366574.2:c.8705C>T p.Ala2902Val p.A2902V ENST00000366574 NM_001035.2 2902 gCt/gTt 0 +RYR3 UCSF GRCh37 15 33954719 33954719 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 72 167 0 ENST00000389232.4:c.4988C>T p.Pro1663Leu p.P1663L ENST00000389232 NM_001036.3 1663 cCc/cTc 0 +RYR3 UCSF GRCh37 15 33833074 33833074 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 69 135 0 ENST00000389232.4:c.629G>A p.Gly210Glu p.G210E ENST00000389232 NM_001036.3 210 gGa/gAa 0 +S100PBP UCSF GRCh37 1 33292145 33292145 + missense_variant Missense_Mutation SNP G G T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 86 175 0 ENST00000373475.5:c.445G>T p.Ala149Ser p.A149S ENST00000373475 NM_022753.3 149 Gca/Tca 0 +S100PBP UCSF GRCh37 1 33293638 33293638 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 46 146 0 ENST00000373475.5:c.876G>A p.Glu292= p.E292= ENST00000373475 NM_022753.3 292 gaG/gaA 0 +S1PR3 UCSF GRCh37 9 91616800 91616800 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 117 45 102 0 ENST00000375846.3:c.685G>A p.Val229Met p.V229M ENST00000375846 229 Gtg/Atg 0 +SAFB UCSF GRCh37 19 5653129 5653129 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 38 95 0 ENST00000588852.1:c.1297G>A p.Val433Met p.V433M ENST00000588852 433 Gtg/Atg 0 +SALL1 UCSF GRCh37 16 51173853 51173853 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 76 105 0 ENST00000251020.4:c.2280C>T p.Pro760= p.P760= ENST00000251020 NM_002968.2 760 ccC/ccT 0 +SAMSN1 UCSF GRCh37 21 15858298 15858298 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 73 193 0 ENST00000285670.2:c.1261G>A p.Asp421Asn p.D421N ENST00000285670 NM_001256370.1 421 Gat/Aat 0 +SBF1 UCSF GRCh37 22 50893548 50893548 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 55 58 0 ENST00000380817.3:c.4578G>A p.Glu1526= p.E1526= ENST00000380817 NM_002972.2 1526 gaG/gaA 0 +SBNO2 UCSF GRCh37 19 1122245 1122245 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 11 22 0 ENST00000361757.3:c.1042C>T p.Leu348Phe p.L348F ENST00000361757 NM_014963.2 348 Ctc/Ttc 0 +SCAF8 UCSF GRCh37 6 155145427 155145427 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 113 192 0 ENST00000367178.3:c.1986G>A p.Ser662= p.S662= ENST00000367178 NM_014892.3 662 tcG/tcA 0 +SCAI UCSF GRCh37 9 127791974 127791974 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 35 105 0 ENST00000373549.4:c.344G>A p.Gly115Glu p.G115E ENST00000373549 NM_173690.4 115 gGa/gAa 0 +SCARA3 UCSF GRCh37 8 27516123 27516123 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 81 152 0 ENST00000301904.3:c.436C>T p.Gln146Ter p.Q146* ENST00000301904 NM_016240.2 146 Cag/Tag 0 +SCARF2 UCSF GRCh37 22 20780139 20780139 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 12 12 0 ENST00000266214.5:c.2139G>A p.Thr713= p.T713= ENST00000266214 NM_153334.4 713 acG/acA 0 +SCARF2 UCSF GRCh37 22 20783609 20783609 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 20 44 0 ENST00000266214.5:c.1458G>A p.Arg486= p.R486= ENST00000266214 NM_153334.4 486 agG/agA 0 +SCEL UCSF GRCh37 13 78182190 78182190 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 2 40 92 0 ENST00000349847.3:c.1158-1G>A p.X386_splice ENST00000349847 NM_144777.2 0 +SCFD1 UCSF GRCh37 14 31204805 31204805 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 50 114 0 ENST00000458591.2:c.1919G>A p.Gly640Glu p.G640E ENST00000458591 NM_016106.3 640 gGa/gAa 0 +SCG2 UCSF GRCh37 2 224463348 224463348 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 123 98 221 0 ENST00000305409.2:c.653G>A p.Arg218Lys p.R218K ENST00000305409 NM_003469.4 218 aGg/aAg 0 +SCG2 UCSF GRCh37 2 224463362 224463362 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 128 108 248 0 ENST00000305409.2:c.639C>T p.Asn213= p.N213= ENST00000305409 NM_003469.4 213 aaC/aaT 0 +SCGB1A1 UCSF GRCh37 11 62189706 62189706 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 66 115 0 ENST00000278282.2:c.69C>T p.Ile23= p.I23= ENST00000278282 NM_003357.4 23 atC/atT 0 +SCN11A UCSF GRCh37 3 38938584 38938584 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 62 117 0 ENST00000302328.3:c.2155G>A p.Gly719Ser p.G719S ENST00000302328 NM_014139.2 719 Ggc/Agc 0 +SCN2A UCSF GRCh37 2 166237114 166237114 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 49 140 0 ENST00000357398.3:c.4321C>T p.Pro1441Ser p.P1441S ENST00000357398 1441 Ccc/Tcc 0 +SCN3A UCSF GRCh37 2 166018830 166018830 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 84 94 0 ENST00000283254.7:c.1019G>A p.Gly340Asp p.G340D ENST00000283254 NM_001081676.1 340 gGc/gAc 0 +SCN4A UCSF GRCh37 17 62028875 62028875 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 72 134 0 ENST00000435607.1:c.2762C>T p.Thr921Ile p.T921I ENST00000435607 NM_000334.4 921 aCc/aTc 0 +SCN8A UCSF GRCh37 12 52162792 52162792 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 97 196 0 ENST00000354534.6:c.3045G>A p.Val1015= p.V1015= ENST00000354534 NM_014191.3 1015 gtG/gtA 0 +SCNN1A UCSF GRCh37 12 6471222 6471222 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 50 117 0 ENST00000360168.3:c.1047C>T p.Asn349= p.N349= ENST00000360168 NM_001159576.1 349 aaC/aaT 0 +SCRIB UCSF GRCh37 8 144896224 144896224 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 8 11 0 ENST00000356994.2:c.224C>T p.Pro75Leu p.P75L ENST00000356994 NM_182706.4 75 cCt/cTt 0 +SCRIB UCSF GRCh37 8 144888643 144888643 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 8 15 0 ENST00000356994.2:c.2280C>T p.Ile760= p.I760= ENST00000356994 NM_182706.4 760 atC/atT 0 +SCRIB UCSF GRCh37 8 144891862 144891862 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 164 41 62 0 ENST00000356994.2:c.1557C>T p.Gly519= p.G519= ENST00000356994 NM_182706.4 519 ggC/ggT 0 +SDCCAG3 UCSF GRCh37 9 139301920 139301920 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 22 36 0 ENST00000357365.3:c.496G>A p.Asp166Asn p.D166N ENST00000357365 NM_001039707.1 166 Gat/Aat 0 +SDCCAG8 UCSF GRCh37 1 243542141 243542141 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 69 137 0 ENST00000366541.3:c.1592C>T p.Ser531Phe p.S531F ENST00000366541 NM_006642.3 531 tCt/tTt 0 +SDK1 UCSF GRCh37 7 4185534 4185534 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 34 58 0 ENST00000404826.2:c.4409C>T p.Thr1470Ile p.T1470I ENST00000404826 NM_152744.3 1470 aCc/aTc 0 +SDK1 UCSF GRCh37 7 3991372 3991372 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 33 92 0 ENST00000404826.2:c.970G>A p.Asp324Asn p.D324N ENST00000404826 NM_152744.3 324 Gac/Aac 0 +SDK2 UCSF GRCh37 17 71429901 71429901 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 54 90 0 ENST00000392650.3:c.1282G>A p.Ala428Thr p.A428T ENST00000392650 NM_001144952.1 428 Gcg/Acg 0 +SDR42E1 UCSF GRCh37 16 82033718 82033718 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 105 88 224 0 ENST00000328945.5:c.180C>T p.His60= p.H60= ENST00000328945 NM_145168.2 60 caC/caT 0 +SEC16A UCSF GRCh37 9 139369238 139369238 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 208 92 199 0 ENST00000313050.7:c.2830G>A p.Asp944Asn p.D944N ENST00000313050 NM_014866.1 944 Gat/Aat 0 +SEC16A UCSF GRCh37 9 139350212 139350212 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 18 30 0 ENST00000313050.7:c.5698C>T p.Leu1900Phe p.L1900F ENST00000313050 NM_014866.1 1900 Ctc/Ttc 0 +SEC16A UCSF GRCh37 9 139351971 139351971 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 47 94 0 ENST00000313050.7:c.5475C>T p.Tyr1825= p.Y1825= ENST00000313050 NM_014866.1 1825 taC/taT 0 +SEC23A UCSF GRCh37 14 39532540 39532540 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 23 67 0 ENST00000307712.6:c.1386G>A p.Glu462= p.E462= ENST00000307712 NM_006364.2 462 gaG/gaA 0 +SEC24C UCSF GRCh37 10 75530134 75530134 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 117 234 0 ENST00000339365.2:c.2959C>T p.Leu987Phe p.L987F ENST00000339365 NM_004922.3 987 Ctc/Ttc 0 +SEC24C UCSF GRCh37 10 75510875 75510875 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 45 87 0 ENST00000339365.2:c.182G>A p.Arg61Lys p.R61K ENST00000339365 NM_004922.3 61 aGa/aAa 0 +SEC61B UCSF GRCh37 9 101984832 101984832 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 26 38 0 ENST00000223641.4:c.8G>A p.Gly3Asp p.G3D ENST00000223641 NM_006808.2 3 gGt/gAt 0 +SECTM1 UCSF GRCh37 17 80280234 80280234 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 37 56 0 ENST00000269389.3:c.550C>T p.Leu184Phe p.L184F ENST00000269389 NM_003004.2 184 Ctc/Ttc 0 +SELO UCSF GRCh37 22 50649208 50649208 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 5 79 92 0 ENST00000380903.2:c.1219G>A p.Ala407Thr p.A407T ENST00000380903 NM_031454.1 407 Gcc/Acc 0 +SEMA3E UCSF GRCh37 7 82997288 82997288 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 70 137 0 ENST00000307792.3:c.1942G>A p.Asp648Asn p.D648N ENST00000307792 NM_012431.2 648 Gat/Aat 0 +SEMA3F UCSF GRCh37 3 50219793 50219793 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 60 137 0 ENST00000002829.3:c.720G>A p.Gln240= p.Q240= ENST00000002829 NM_004186.3 240 caG/caA 0 +SEMA4B UCSF GRCh37 15 90771584 90771584 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 57 98 0 ENST00000411539.2:c.2223G>A p.Arg741= p.R741= ENST00000411539 NM_198925.2 741 cgG/cgA 0 +SEMA4C UCSF GRCh37 2 97533552 97533552 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 58 121 0 ENST00000305476.5:c.72G>A p.Trp24Ter p.W24* ENST00000305476 NM_017789.4 24 tgG/tgA 0 +SEMA6A UCSF GRCh37 5 115782564 115782564 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 53 115 0 ENST00000343348.6:c.2838C>T p.His946= p.H946= ENST00000343348 NM_020796.3 946 caC/caT 0 +SENP1 UCSF GRCh37 12 48458896 48458896 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P10_Rec Untested WXS Illumina HiSeq 68 0 ENST00000004980.5:c.1227delA p.Gly410ValfsTer4 p.G410Vfs*4 ENST00000004980 409 aaA/aa 0 +SENP1 UCSF GRCh37 12 48441857 48441857 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 53 161 0 ENST00000004980.5:c.1618G>A p.Asp540Asn p.D540N ENST00000004980 540 Gac/Aac 0 +SERAC1 UCSF GRCh37 6 158551514 158551514 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 25 60 0 ENST00000367104.3:c.743G>A p.Gly248Asp p.G248D ENST00000367104 NM_032861.3 248 gGt/gAt 0 +SERPINA11 UCSF GRCh37 14 94914727 94914727 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 110 182 0 ENST00000334708.3:c.385C>T p.Pro129Ser p.P129S ENST00000334708 NM_001080451.1 129 Ccc/Tcc 0 +SERPINH1 UCSF GRCh37 11 75277902 75277902 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 38 75 0 ENST00000524558.1:c.508C>T p.Leu170= p.L170= ENST00000524558 170 Ctg/Ttg 0 +SERPINI2 UCSF GRCh37 3 167159929 167159929 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 27 87 0 ENST00000476257.1:c.1186G>A p.Glu396Lys p.E396K ENST00000476257 NM_006217.4 396 Gag/Aag 0 +SESN2 UCSF GRCh37 1 28601468 28601468 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 57 99 0 ENST00000253063.3:c.1153G>A p.Asp385Asn p.D385N ENST00000253063 NM_031459.4 385 Gac/Aac 0 +SETD1A UCSF GRCh37 16 30977210 30977210 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 58 100 0 ENST00000262519.8:c.2008G>A p.Gly670Arg p.G670R ENST00000262519 NM_014712.1 670 Ggg/Agg 0 +SETD1B UCSF GRCh37 12 122261376 122261376 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 9 16 0 ENST00000267197.5:c.4762G>A p.Glu1588Lys p.E1588K ENST00000267197 NM_015048.1 1588 Gaa/Aaa 0 +SEZ6 UCSF GRCh37 17 27286234 27286234 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.000,snp132_rs117276370 P10_Rec Untested WXS Illumina HiSeq 68 74 125 1 ENST00000317338.12:c.1916G>A p.Arg639His p.R639H ENST00000317338 639 cGc/cAc 0 +SF1 UCSF GRCh37 11 64533474 64533474 + intron_variant Intron SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 13 14 0 ENST00000377387.1:c.1958-484C>T *653* ENST00000377387 NM_001178030.1 0 +SF3A1 UCSF GRCh37 22 30741012 30741012 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 111 163 0 ENST00000215793.8:c.561G>A p.Gln187= p.Q187= ENST00000215793 NM_005877.4 187 caG/caA 0 +SF3B3 UCSF GRCh37 16 70566422 70566422 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 95 198 0 ENST00000302516.5:c.611C>T p.Thr204Ile p.T204I ENST00000302516 NM_012426.4 204 aCc/aTc 0 +SGK1 UCSF GRCh37 6 134528570 134528570 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 70 167 0 ENST00000367858.5:c.286-1G>A p.X96_splice ENST00000367858 NM_001143676.1 0 +SGPL1 UCSF GRCh37 10 72631678 72631678 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 51 116 0 ENST00000373202.3:c.994C>T p.Pro332Ser p.P332S ENST00000373202 NM_003901.3 332 Cca/Tca 0 +SGPP1 UCSF GRCh37 14 64153035 64153035 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 81 184 0 ENST00000247225.6:c.1114G>A p.Gly372Arg p.G372R ENST00000247225 NM_030791.2 372 Ggg/Agg 0 +SH2B1 UCSF GRCh37 16 28877820 28877820 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 42 89 0 ENST00000322610.8:c.405C>T p.Ser135= p.S135= ENST00000322610 135 tcC/tcT 0 +SH2D5 UCSF GRCh37 1 21050210 21050210 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 13 26 0 ENST00000444387.2:c.817G>A p.Ala273Thr p.A273T ENST00000444387 NM_001103161.1 273 Gca/Aca 0 +SH3BP4 UCSF GRCh37 2 235949623 235949623 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 66 140 0 ENST00000409212.1:c.210C>T p.Asn70= p.N70= ENST00000409212 70 aaC/aaT 0 +SH3GLB2 UCSF GRCh37 9 131777142 131777142 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 134 67 157 0 ENST00000372564.3:c.376G>A p.Gly126Arg p.G126R ENST00000372564 NM_020145.2 126 Gga/Aga 0 +SH3GLB2 UCSF GRCh37 9 131772104 131772104 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 13 27 0 ENST00000372564.3:c.785C>T p.Thr262Ile p.T262I ENST00000372564 NM_020145.2 262 aCc/aTc 0 +SH3KBP1 UCSF GRCh37 X 19564131 19564131 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 64 124 0 ENST00000397821.3:c.1532G>A p.Ser511Asn p.S511N ENST00000397821 NM_031892.2 511 aGt/aAt 0 +SH3KBP1 UCSF GRCh37 X 19555892 19555892 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 77 151 0 ENST00000397821.3:c.1899G>A p.Glu633= p.E633= ENST00000397821 NM_031892.2 633 gaG/gaA 0 +SH3PXD2B UCSF GRCh37 5 171849445 171849445 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 19 41 0 ENST00000311601.5:c.131G>A p.Arg44His p.R44H ENST00000311601 NM_001017995.2 44 cGc/cAc 0 +SH3RF3 UCSF GRCh37 2 109964222 109964222 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 48 108 0 ENST00000309415.6:c.666C>T p.Val222= p.V222= ENST00000309415 NM_001099289.1 222 gtC/gtT 0 +SH3TC2 UCSF GRCh37 5 148406208 148406208 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 63 197 0 ENST00000515425.1:c.2980C>T p.Leu994Phe p.L994F ENST00000515425 NM_024577.3 994 Ctc/Ttc 0 +SHB UCSF GRCh37 9 38068081 38068081 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 9 10 0 ENST00000377707.3:c.562G>A p.Val188Met p.V188M ENST00000377707 NM_003028.2 188 Gtg/Atg 0 +SHC1 UCSF GRCh37 1 154942858 154942858 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 29 66 0 ENST00000448116.2:c.145C>T p.Leu49= p.L49= ENST00000448116 NM_001130040.1 49 Ctg/Ttg 0 +SHCBP1L UCSF GRCh37 1 182908644 182908644 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 30 77 0 ENST00000367547.3:c.815G>A p.Ser272Asn p.S272N ENST00000367547 NM_030933.2 272 aGt/aAt 0 +SHROOM4 UCSF GRCh37 X 50377013 50377013 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 41 98 0 ENST00000376020.2:c.2060C>T p.Pro687Leu p.P687L ENST00000376020 NM_020717.3 687 cCt/cTt 0 +SIDT1 UCSF GRCh37 3 113251941 113251941 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 7 17 0 ENST00000264852.4:c.73C>T p.Pro25Ser p.P25S ENST00000264852 NM_017699.2 25 Ccg/Tcg 0 +SIGLEC1 UCSF GRCh37 20 3672566 3672566 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 38 92 0 ENST00000344754.4:c.4314G>A p.Gly1438= p.G1438= ENST00000344754 NM_023068.3 1438 ggG/ggA 0 +SIGLEC8 UCSF GRCh37 19 51961292 51961292 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 116 229 0 ENST00000321424.3:c.350G>A p.Arg117Lys p.R117K ENST00000321424 NM_014442.2 117 aGg/aAg 0 +SIGLEC8 UCSF GRCh37 19 51960915 51960915 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 46 126 0 ENST00000321424.3:c.533C>T p.Pro178Leu p.P178L ENST00000321424 NM_014442.2 178 cCc/cTc 0 +SIN3A UCSF GRCh37 15 75664459 75664459 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 52 133 0 ENST00000394947.3:c.3683C>T p.Ala1228Val p.A1228V ENST00000394947 NM_001145358.1 1228 gCa/gTa 0 +SIPA1 UCSF GRCh37 11 65408730 65408730 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 56 106 0 ENST00000394224.3:c.338C>T p.Pro113Leu p.P113L ENST00000394224 NM_153253.29 113 cCt/cTt 0 +SIPA1L2 UCSF GRCh37 1 232577605 232577605 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 11 18 33 0 ENST00000366630.1:c.3447C>T p.Ser1149= p.S1149= ENST00000366630 1149 tcC/tcT 0 +SIRPA UCSF GRCh37 20 1902070 1902070 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 67 143 0 ENST00000358771.4:c.466C>T p.Pro156Ser p.P156S ENST00000358771 NM_001040023.1 156 Cct/Tct 0 +SIT1 UCSF GRCh37 9 35650018 35650018 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 19 35 0 ENST00000259608.3:c.418C>T p.Pro140Ser p.P140S ENST00000259608 NM_014450.2 140 Ccc/Tcc 0 +SIX1 UCSF GRCh37 14 61113237 61113237 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 35 42 88 0 ENST00000247182.6:c.619G>A p.Glu207Lys p.E207K ENST00000247182 NM_005982.3 207 Gaa/Aaa 0 +SKIL UCSF GRCh37 3 170078528 170078528 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 122 118 214 0 ENST00000458537.3:c.409C>T p.Pro137Ser p.P137S ENST00000458537 NM_001248008.1 137 Cct/Tct 0 +SKIV2L UCSF GRCh37 6 31935054 31935054 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 70 106 0 ENST00000375394.2:c.2483G>A p.Arg828His p.R828H ENST00000375394 NM_006929.4 828 cGc/cAc 0 +SKIV2L UCSF GRCh37 6 31928006 31928006 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 141 135 226 0 ENST00000375394.2:c.246G>A p.Gln82= p.Q82= ENST00000375394 NM_006929.4 82 caG/caA 0 +SKIV2L2 UCSF GRCh37 5 54637533 54637533 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 44 140 0 ENST00000230640.5:c.715G>A p.Gly239Ser p.G239S ENST00000230640 NM_015360.4 239 Ggt/Agt 0 +SLC10A1 UCSF GRCh37 14 70263533 70263533 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 29 65 0 ENST00000216540.4:c.340G>A p.Gly114Arg p.G114R ENST00000216540 NM_003049.3 114 Ggg/Agg 0 +SLC12A1 UCSF GRCh37 15 48548020 48548020 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 52 127 0 ENST00000396577.3:c.1955G>A p.Gly652Asp p.G652D ENST00000396577 NM_001184832.1 652 gGc/gAc 0 +SLC12A1 UCSF GRCh37 15 48559879 48559879 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 121 93 222 0 ENST00000396577.3:c.2276G>A p.Gly759Asp p.G759D ENST00000396577 NM_001184832.1 759 gGt/gAt 0 +SLC12A5 UCSF GRCh37 20 44683654 44683654 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 28 58 0 ENST00000454036.2:c.2848G>A p.Glu950Lys p.E950K ENST00000454036 NM_001134771.1 950 Gag/Aag 0 +SLC12A8 UCSF GRCh37 3 124826835 124826835 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 48 108 0 ENST00000393469.4:c.1195G>A p.Asp399Asn p.D399N ENST00000393469 NM_001195483.1 399 Gac/Aac 0 +SLC17A8 UCSF GRCh37 12 100813607 100813607 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 54 132 0 ENST00000323346.5:c.1440G>A p.Trp480Ter p.W480* ENST00000323346 NM_001145288.1 480 tgG/tgA 0 +SLC17A9 UCSF GRCh37 20 61593991 61593991 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 43 70 0 ENST00000370351.4:c.513G>A p.Gly171= p.G171= ENST00000370351 NM_022082.3 171 ggG/ggA 0 +SLC18A3 UCSF GRCh37 10 50818864 50818864 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 7 17 0 ENST00000374115.3:c.78G>A p.Gln26= p.Q26= ENST00000374115 NM_003055.2 26 caG/caA 0 +SLC20A1 UCSF GRCh37 2 113417272 113417272 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 102 99 197 0 ENST00000272542.3:c.1540C>T p.Leu514Phe p.L514F ENST00000272542 NM_005415.4 514 Ctc/Ttc 0 +SLC22A12 UCSF GRCh37 11 64359268 64359268 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 39 57 0 ENST00000377574.1:c.240C>T p.Gly80= p.G80= ENST00000377574 NM_144585.3 80 ggC/ggT 0 +SLC22A15 UCSF GRCh37 1 116569552 116569552 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 119 116 252 0 ENST00000369503.4:c.637C>T p.Gln213Ter p.Q213* ENST00000369503 NM_018420.2 213 Caa/Taa 0 +SLC22A25 UCSF GRCh37 11 62996921 62996921 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 79 163 0 ENST00000306494.6:c.204C>T p.Ser68= p.S68= ENST00000306494 NM_199352.3 68 agC/agT 0 +SLC22A7 UCSF GRCh37 6 43266456 43266456 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 44 96 0 ENST00000372585.5:c.360C>T p.Asp120= p.D120= ENST00000372585 NM_153320.2 120 gaC/gaT 0 +SLC22A8 UCSF GRCh37 11 62762197 62762197 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 43 106 0 ENST00000336232.2:c.1033G>A p.Ala345Thr p.A345T ENST00000336232 NM_001184736.1 345 Gct/Act 0 +SLC25A2 UCSF GRCh37 5 140682715 140682715 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 82 151 0 ENST00000239451.4:c.718C>T p.Leu240Phe p.L240F ENST00000239451 NM_031947.2 240 Ctt/Ttt 0 +SLC25A23 UCSF GRCh37 19 6454397 6454397 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 83 163 0 ENST00000301454.4:c.732C>T p.Gly244= p.G244= ENST00000301454 NM_024103.2 244 ggC/ggT 0 +SLC25A47 UCSF GRCh37 14 100793657 100793657 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 48 73 0 ENST00000361529.3:c.277C>T p.Pro93Ser p.P93S ENST00000361529 NM_207117.2 93 Ccc/Tcc 0 +SLC25A47 UCSF GRCh37 14 100792129 100792129 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 13 12 30 0 ENST00000361529.3:c.33C>T p.Val11= p.V11= ENST00000361529 NM_207117.2 11 gtC/gtT 0 +SLC26A3 UCSF GRCh37 7 107427920 107427920 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 75 204 0 ENST00000340010.5:c.770C>T p.Thr257Ile p.T257I ENST00000340010 NM_000111.2 257 aCt/aTt 0 +SLC26A7 UCSF GRCh37 8 92406050 92406050 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 246 70 188 0 ENST00000309536.2:c.1802G>A p.Ser601Asn p.S601N ENST00000309536 NM_134266.1 601 aGt/aAt 0 +SLC26A8 UCSF GRCh37 6 35945047 35945047 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 75 149 0 ENST00000490799.1:c.1107C>T p.Ser369= p.S369= ENST00000490799 NM_052961.3 369 tcC/tcT 0 +SLC27A1 UCSF GRCh37 19 17608123 17608123 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 21 36 0 ENST00000252595.7:c.1056G>A p.Ala352= p.A352= ENST00000252595 NM_198580.1 352 gcG/gcA 0 +SLC27A6 UCSF GRCh37 5 128368798 128368798 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 33 81 0 ENST00000262462.4:c.1684-1G>A p.X562_splice ENST00000262462 0 +SLC29A1 UCSF GRCh37 6 44197742 44197742 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 28 69 0 ENST00000393841.1:c.413C>T p.Pro138Leu p.P138L ENST00000393841 NM_001078177.1 138 cCc/cTc 0 +SLC2A12 UCSF GRCh37 6 134349911 134349911 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 82 167 0 ENST00000275230.5:c.1052C>T p.Ser351Phe p.S351F ENST00000275230 NM_145176.2 351 tCc/tTc 0 +SLC2A8 UCSF GRCh37 9 130167116 130167116 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 31 55 0 ENST00000373371.3:c.996C>T p.Ser332= p.S332= ENST00000373371 NM_014580.4 332 agC/agT 0 +SLC32A1 UCSF GRCh37 20 37356347 37356347 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 52 71 0 ENST00000217420.1:c.643G>A p.Val215Met p.V215M ENST00000217420 NM_080552.2 215 Gtg/Atg 0 +SLC34A1 UCSF GRCh37 5 176814997 176814997 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 24 40 0 ENST00000324417.5:c.647C>T p.Ala216Val p.A216V ENST00000324417 NM_003052.4 216 gCc/gTc 0 +SLC34A3 UCSF GRCh37 9 140130583 140130583 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 62 31 68 0 ENST00000538474.1:c.1515G>A p.Gly505= p.G505= ENST00000538474 NM_001177317.1 505 ggG/ggA 0 +SLC36A1 UCSF GRCh37 5 150838470 150838470 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 64 49 118 0 ENST00000243389.3:c.117G>A p.Gln39= p.Q39= ENST00000243389 NM_078483.2 39 caG/caA 0 +SLC38A2 UCSF GRCh37 12 46756118 46756118 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 33 74 0 ENST00000256689.5:c.1371C>T p.Phe457= p.F457= ENST00000256689 NM_018976.4 457 ttC/ttT 0 +SLC39A11 UCSF GRCh37 17 70645311 70645311 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 30 61 0 ENST00000542342.2:c.789C>T p.Phe263= p.F263= ENST00000542342 NM_001159770.1 263 ttC/ttT 0 +SLC39A12 UCSF GRCh37 10 18292187 18292187 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 169 80 206 0 ENST00000377369.2:c.1847G>A p.Gly616Glu p.G616E ENST00000377369 NM_001145195.1 616 gGa/gAa 0 +SLC39A14 UCSF GRCh37 8 22277162 22277162 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 86 153 0 ENST00000359741.5:c.1430C>T p.Thr477Ile p.T477I ENST00000359741 NM_015359.4 477 aCc/aTc 0 +SLC39A4 UCSF GRCh37 8 145641314 145641314 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 9 20 0 ENST00000301305.3:c.354C>T p.Leu118= p.L118= ENST00000301305 NM_130849.3 118 ctC/ctT 0 +SLC41A3 UCSF GRCh37 3 125786943 125786943 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 57 125 0 ENST00000315891.6:c.120C>T p.Leu40= p.L40= ENST00000315891 NM_017836.3 40 ctC/ctT 0 +SLC44A1 UCSF GRCh37 9 108061522 108061522 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 36 121 0 ENST00000374720.3:c.58C>T p.Pro20Ser p.P20S ENST00000374720 NM_080546.3 20 Ccg/Tcg 0 +SLC44A2 UCSF GRCh37 19 10742341 10742341 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 42 37 81 0 ENST00000335757.5:c.542G>A p.Gly181Asp p.G181D ENST00000335757 181 gGt/gAt 0 +SLC45A2 UCSF GRCh37 5 33947310 33947310 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 113 109 219 0 ENST00000296589.4:c.1326C>T p.Pro442= p.P442= ENST00000296589 NM_016180.3 442 ccC/ccT 0 +SLC4A10 UCSF GRCh37 2 162757488 162757488 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 56 167 0 ENST00000446997.1:c.1409G>A p.Gly470Glu p.G470E ENST00000446997 NM_001178015.1 470 gGa/gAa 0 +SLC4A2 UCSF GRCh37 7 150772436 150772436 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 68 81 0 ENST00000485713.1:c.3142C>T p.Leu1048Phe p.L1048F ENST00000485713 NM_001199692.1 1048 Ctc/Ttc 0 +SLC4A3 UCSF GRCh37 2 220504259 220504259 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 44 83 0 ENST00000373762.3:c.3160G>A p.Asp1054Asn p.D1054N ENST00000373762 NM_005070.3 1054 Gac/Aac 0 +SLC4A5 UCSF GRCh37 2 74492354 74492354 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 70 136 0 ENST00000377634.4:c.439G>A p.Glu147Lys p.E147K ENST00000377634 147 Gaa/Aaa 0 +SLC4A9 UCSF GRCh37 5 139744000 139744000 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 52 97 0 ENST00000230993.6:c.1513G>A p.Ala505Thr p.A505T ENST00000230993 NM_001258428.1 505 Gct/Act 0 +SLC5A10 UCSF GRCh37 17 18918429 18918429 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 24 36 0 ENST00000395647.2:c.1206C>T p.Asn402= p.N402= ENST00000395647 NM_152351.4 402 aaC/aaT 0 +SLC5A2 UCSF GRCh37 16 31499971 31499971 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 10 17 0 ENST00000330498.3:c.1158G>A p.Met386Ile p.M386I ENST00000330498 NM_003041.3 386 atG/atA 0 +SLC5A5 UCSF GRCh37 19 17994721 17994721 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 9 9 9 0 ENST00000222248.3:c.1392G>A p.Thr464= p.T464= ENST00000222248 NM_000453.2 464 acG/acA 0 +SLC5A8 UCSF GRCh37 12 101581270 101581270 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 52 139 0 ENST00000536262.2:c.857G>A p.Gly286Glu p.G286E ENST00000536262 NM_145913.3 286 gGa/gAa 0 +SLC6A17 UCSF GRCh37 1 110717545 110717545 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 29 69 0 ENST00000331565.4:c.716G>A p.Gly239Glu p.G239E ENST00000331565 NM_001010898.2 239 gGg/gAg 0 +SLC7A14 UCSF GRCh37 3 170219032 170219032 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 57 96 0 ENST00000231706.5:c.407G>A p.Gly136Asp p.G136D ENST00000231706 NM_020949.2 136 gGc/gAc 0 +SLC7A5 UCSF GRCh37 16 87873374 87873374 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 35 64 0 ENST00000261622.4:c.873G>A p.Leu291= p.L291= ENST00000261622 NM_003486.5 291 ctG/ctA 0 +SLC8A2 UCSF GRCh37 19 47935628 47935628 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 54 86 0 ENST00000236877.6:c.2185C>T p.Leu729= p.L729= ENST00000236877 NM_015063.2 729 Ctg/Ttg 0 +SLCO1B1 UCSF GRCh37 12 21377716 21377716 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 75 157 0 ENST00000256958.2:c.1808C>T p.Ser603Phe p.S603F ENST00000256958 NM_006446.4 603 tCc/tTc 0 +SLCO1B7 UCSF GRCh37 12 21175906 21175906 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 125 101 211 0 ENST00000421593.2:c.463G>A p.Glu155Lys p.E155K ENST00000421593 NM_001009562.4 155 Gaa/Aaa 0 +SLCO1B7 UCSF GRCh37 12 21176207 21176207 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 62 190 0 ENST00000421593.2:c.572G>A p.Gly191Glu p.G191E ENST00000421593 NM_001009562.4 191 gGa/gAa 0 +SLCO3A1 UCSF GRCh37 15 92663699 92663699 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 93 147 0 ENST00000318445.6:c.1014C>T p.Ile338= p.I338= ENST00000318445 NM_013272.3 338 atC/atT 0 +SLFN11 UCSF GRCh37 17 33689878 33689878 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 93 171 0 ENST00000394566.1:c.949G>A p.Val317Ile p.V317I ENST00000394566 NM_001104587.1 317 Gta/Ata 0 +SLFN5 UCSF GRCh37 17 33592592 33592592 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 100 157 1 ENST00000299977.4:c.2361G>A p.Pro787= p.P787= ENST00000299977 NM_144975.3 787 ccG/ccA 0 +SLIT2 UCSF GRCh37 4 20618640 20618640 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 53 128 0 ENST00000504154.1:c.3955G>A p.Asp1319Asn p.D1319N ENST00000504154 NM_004787.1 1319 Gac/Aac 0 +SLIT3 UCSF GRCh37 5 168233465 168233465 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 50 106 1 ENST00000519560.1:c.921G>A p.Glu307= p.E307= ENST00000519560 NM_003062.3 307 gaG/gaA 0 +SLITRK3 UCSF GRCh37 3 164907600 164907600 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 92 252 0 ENST00000475390.1:c.1019G>A p.Arg340Gln p.R340Q ENST00000475390 340 cGa/cAa 0 +SLITRK3 UCSF GRCh37 3 164907019 164907019 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 65 140 0 ENST00000475390.1:c.1600C>T p.Leu534= p.L534= ENST00000475390 534 Ctg/Ttg 0 +SLK UCSF GRCh37 10 105727625 105727625 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 73 142 0 ENST00000369755.3:c.122G>A p.Gly41Asp p.G41D ENST00000369755 NM_014720.2 41 gGc/gAc 0 +SLX4 UCSF GRCh37 16 3651005 3651005 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 40 97 0 ENST00000294008.3:c.1138G>A p.Gly380Ser p.G380S ENST00000294008 NM_032444.2 380 Ggt/Agt 0 +SMAD4 UCSF GRCh37 18 48604826 48604826 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 82 58 147 0 ENST00000342988.3:c.1648C>T p.Pro550Ser p.P550S ENST00000342988 NM_005359.5 550 Cct/Tct 0 +SMARCA2 UCSF GRCh37 9 2123736 2123736 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 26 52 0 ENST00000382203.1:c.3780G>A p.Arg1260= p.R1260= ENST00000382203 1260 cgG/cgA 0 +SMARCC1 UCSF GRCh37 3 47663775 47663775 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 73 220 0 ENST00000254480.5:c.2703G>A p.Glu901= p.E901= ENST00000254480 NM_003074.3 901 gaG/gaA 0 +SMCR8 UCSF GRCh37 17 18220963 18220963 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 105 154 0 ENST00000406438.3:c.1860G>A p.Arg620= p.R620= ENST00000406438 NM_144775.2 620 agG/agA 0 +SMG6 UCSF GRCh37 17 2200618 2200618 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 44 121 0 ENST00000263073.6:c.2070G>A p.Gln690= p.Q690= ENST00000263073 NM_017575.4 690 caG/caA 0 +SMG8 UCSF GRCh37 17 57290819 57290819 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 114 225 0 ENST00000543872.2:c.2635G>A p.Ala879Thr p.A879T ENST00000543872 879 Gct/Act 0 +SMG9 UCSF GRCh37 19 44251629 44251629 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 46 86 0 ENST00000270066.6:c.553G>A p.Asp185Asn p.D185N ENST00000270066 NM_019108.2 185 Gat/Aat 0 +SMG9 UCSF GRCh37 19 44251950 44251950 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 29 19 41 0 ENST00000270066.6:c.325G>A p.Gly109Arg p.G109R ENST00000270066 NM_019108.2 109 Ggg/Agg 0 +SMOX UCSF GRCh37 20 4164244 4164244 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 32 93 0 ENST00000305958.4:c.1473G>A p.Gly491= p.G491= ENST00000305958 NM_175839.2 491 ggG/ggA 0 +SMPD3 UCSF GRCh37 16 68405569 68405569 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 23 37 0 ENST00000219334.5:c.516C>T p.Asp172= p.D172= ENST00000219334 NM_018667.3 172 gaC/gaT 0 +SMPD4 UCSF GRCh37 2 130911459 130911459 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 28 102 0 ENST00000409031.1:c.1826C>T p.Ser609Phe p.S609F ENST00000409031 NM_017951.4 609 tCc/tTc 0 +SMYD4 UCSF GRCh37 17 1690757 1690757 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 11 18 0 ENST00000305513.7:c.1679C>T p.Ser560Leu p.S560L ENST00000305513 NM_052928.2 560 tCa/tTa 0 +SNAP47 UCSF GRCh37 1 227935765 227935765 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 38 90 0 ENST00000366759.4:c.463G>A p.Ala155Thr p.A155T ENST00000366759 NM_053052.3 155 Gca/Aca 0 +SNAP91 UCSF GRCh37 6 84302924 84302924 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 88 82 163 0 ENST00000439399.2:c.1751C>T p.Pro584Leu p.P584L ENST00000439399 NM_014841.2 584 cCt/cTt 0 +SNAPC4 UCSF GRCh37 9 139272750 139272750 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 15 20 0 ENST00000298532.2:c.3529G>A p.Glu1177Lys p.E1177K ENST00000298532 NM_003086.2 1177 Gag/Aag 0 +SNAPC4 UCSF GRCh37 9 139273417 139273417 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 10 23 0 ENST00000298532.2:c.2862G>A p.Gly954= p.G954= ENST00000298532 NM_003086.2 954 ggG/ggA 0 +SND1 UCSF GRCh37 7 127338952 127338952 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 37 114 0 ENST00000354725.3:c.373G>A p.Glu125Lys p.E125K ENST00000354725 NM_014390.2 125 Gaa/Aaa 0 +SNRNP70 UCSF GRCh37 19 49611115 49611115 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 9 14 0 ENST00000598441.1:c.729G>A p.Glu243= p.E243= ENST00000598441 243 gaG/gaA 0 +SNTB1 UCSF GRCh37 8 121823749 121823749 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 25 29 0 ENST00000395601.3:c.335G>A p.Gly112Asp p.G112D ENST00000395601 NM_021021.3 112 gGc/gAc 0 +SNX10 UCSF GRCh37 7 26411640 26411641 + frameshift_variant Frame_Shift_Del DEL TA TA - NOVEL P10_Rec Untested WXS Illumina HiSeq 56 0 ENST00000338523.4:c.512_513del p.Tyr171Ter p.Y171* ENST00000338523 NM_013322.2 171 TAt/t 0 +SNX14 UCSF GRCh37 6 86217778 86217778 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 34 60 0 ENST00000314673.3:c.2654-1G>A p.X885_splice ENST00000314673 NM_153816.3 0 +SNX25 UCSF GRCh37 4 186272737 186272737 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 57 135 0 ENST00000504273.1:c.1948C>T p.Pro650Ser p.P650S ENST00000504273 650 Cct/Tct 0 +SNX3 UCSF GRCh37 6 108582003 108582003 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 25 56 0 ENST00000230085.8:c.123C>T p.Val41= p.V41= ENST00000230085 NM_003795.4 41 gtC/gtT 0 +SNX30 UCSF GRCh37 9 115598667 115598667 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 199 96 159 0 ENST00000374232.3:c.792G>A p.Gln264= p.Q264= ENST00000374232 NM_001012994.1 264 caG/caA 0 +SOCS4 UCSF GRCh37 14 55510165 55510165 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 66 146 0 ENST00000395472.2:c.406C>T p.Pro136Ser p.P136S ENST00000395472 NM_080867.2 136 Cct/Tct 0 +SOCS7 UCSF GRCh37 17 36552203 36552203 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 44 92 0 ENST00000577233.1:c.1728G>A p.Glu576= p.E576= ENST00000577233 NM_014598.2 576 gaG/gaA 0 +SON UCSF GRCh37 21 34923735 34923735 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 104 199 0 ENST00000356577.4:c.2198C>T p.Ser733Phe p.S733F ENST00000356577 NM_138927.2 733 tCc/tTc 0 +SON UCSF GRCh37 21 34927520 34927520 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 50 78 0 ENST00000356577.4:c.5983C>T p.Pro1995Ser p.P1995S ENST00000356577 NM_138927.2 1995 Cca/Tca 0 +SORBS1 UCSF GRCh37 10 97131152 97131152 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 59 139 0 ENST00000371247.2:c.1836G>A p.Gln612= p.Q612= ENST00000371247 612 caG/caA 0 +SORBS2 UCSF GRCh37 4 186508806 186508806 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 12 42 0 ENST00000355634.5:c.3578C>T p.Pro1193Leu p.P1193L ENST00000355634 NM_001270771.1 1193 cCc/cTc 0 +SOX13 UCSF GRCh37 1 204095146 204095146 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 56 96 0 ENST00000367204.1:c.1753G>A p.Glu585Lys p.E585K ENST00000367204 NM_005686.2 585 Gag/Aag 0 +SOX15 UCSF GRCh37 17 7492604 7492604 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 13 32 0 ENST00000250055.2:c.391C>T p.Pro131Ser p.P131S ENST00000250055 NM_006942.1 131 Cct/Tct 0 +SOX2 UCSF GRCh37 3 181431096 181431096 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 12 22 0 ENST00000325404.1:c.948C>T p.His316= p.H316= ENST00000325404 NM_003106.3 316 caC/caT 0 +SOX6 UCSF GRCh37 11 16362714 16362714 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 86 143 0 ENST00000396356.3:c.81G>A p.Arg27= p.R27= ENST00000396356 NM_033326.3 27 agG/agA 0 +SOX7 UCSF GRCh37 8 10587927 10587927 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 15 11 24 0 ENST00000304501.1:c.17G>A p.Gly6Glu p.G6E ENST00000304501 NM_031439.3 6 gGa/gAa 0 +SP7 UCSF GRCh37 12 53722435 53722435 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 38 101 0 ENST00000536324.2:c.791G>A p.Gly264Glu p.G264E ENST00000536324 NM_001173467.1 264 gGg/gAg 0 +SPAG4 UCSF GRCh37 20 34207233 34207233 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 38 101 0 ENST00000374273.3:c.909+1G>A p.X303_splice ENST00000374273 NM_003116.1 0 +SPAG5 UCSF GRCh37 17 26919902 26919902 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 115 128 226 0 ENST00000321765.5:c.360C>T p.Asp120= p.D120= ENST00000321765 NM_006461.3 120 gaC/gaT 0 +SPAG6 UCSF GRCh37 10 22653922 22653922 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 47 110 0 ENST00000376624.3:c.262C>T p.Leu88Phe p.L88F ENST00000376624 NM_012443.3 88 Ctt/Ttt 0 +SPATA18 UCSF GRCh37 4 52946055 52946055 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 109 90 210 0 ENST00000295213.4:c.1325G>A p.Gly442Glu p.G442E ENST00000295213 NM_145263.2 442 gGa/gAa 0 +SPATS2 UCSF GRCh37 12 49912891 49912891 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 35 69 0 ENST00000553127.1:c.934C>T p.Leu312Phe p.L312F ENST00000553127 312 Ctt/Ttt 0 +SPDYA UCSF GRCh37 2 29039088 29039088 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 61 125 0 ENST00000334056.5:c.208G>A p.Asp70Asn p.D70N ENST00000334056 NM_182756.3 70 Gat/Aat 0 +SPEF1 UCSF GRCh37 20 3759405 3759405 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 38 63 0 ENST00000379756.3:c.467G>A p.Gly156Glu p.G156E ENST00000379756 NM_015417.4 156 gGg/gAg 0 +SPEN UCSF GRCh37 1 16262589 16262589 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 39 44 82 0 ENST00000375759.3:c.9854C>T p.Pro3285Leu p.P3285L ENST00000375759 NM_015001.2 3285 cCt/cTt 0 +SPEN UCSF GRCh37 1 16254682 16254682 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 90 186 0 ENST00000375759.3:c.1947C>T p.Asp649= p.D649= ENST00000375759 NM_015001.2 649 gaC/gaT 0 +SPG11 UCSF GRCh37 15 44865887 44865887 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 46 106 0 ENST00000261866.7:c.6063G>A p.Arg2021= p.R2021= ENST00000261866 NM_025137.3 2021 cgG/cgA 0 +SPON1 UCSF GRCh37 11 14284274 14284274 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 107 215 0 ENST00000310358.7:n.2548C>T *850* ENST00000310358 0 +SPTBN5 UCSF GRCh37 15 42145961 42145961 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 23 38 0 ENST00000320955.6:c.9799G>A p.Glu3267Lys p.E3267K ENST00000320955 NM_016642.3 3267 Gag/Aag 0 +SPTBN5 UCSF GRCh37 15 42143262 42143262 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 39 76 0 ENST00000320955.6:c.10830C>T p.Ser3610= p.S3610= ENST00000320955 NM_016642.3 3610 tcC/tcT 0 +SPTLC2 UCSF GRCh37 14 78028832 78028832 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 43 88 0 ENST00000216484.2:c.757G>A p.Gly253Ser p.G253S ENST00000216484 NM_004863.3 253 Ggt/Agt 0 +SQLE UCSF GRCh37 8 126034070 126034070 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 278 86 210 0 ENST00000265896.5:c.1608G>A p.Lys536= p.K536= ENST00000265896 NM_003129.3 536 aaG/aaA 0 +SRA1 UCSF GRCh37 5 139931739 139931739 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0047 P10_Rec Untested WXS Illumina HiSeq 36 21 48 0 ENST00000336283.6:c.218C>T p.Pro73Leu p.P73L ENST00000336283 NM_001035235.3 73 cCc/cTc 0 +SRCAP UCSF GRCh37 16 30749234 30749234 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 42 111 0 ENST00000262518.4:c.7873C>T p.Pro2625Ser p.P2625S ENST00000262518 NM_006662.2 2625 Cca/Tca 0 +SRCAP UCSF GRCh37 16 30749404 30749404 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 47 100 0 ENST00000262518.4:c.8043G>A p.Lys2681= p.K2681= ENST00000262518 NM_006662.2 2681 aaG/aaA 0 +SREBF1 UCSF GRCh37 17 17722445 17722445 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 52 107 0 ENST00000355815.4:c.1040C>T p.Ser347Phe p.S347F ENST00000355815 NM_001005291.2 347 tCt/tTt 0 +SREBF1 UCSF GRCh37 17 17719820 17719820 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 7 9 18 0 ENST00000355815.4:c.2088C>T p.Ala696= p.A696= ENST00000355815 NM_001005291.2 696 gcC/gcT 0 +SRP68 UCSF GRCh37 17 74053530 74053530 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 55 147 0 ENST00000307877.2:c.932G>A p.Arg311His p.R311H ENST00000307877 NM_014230.3 311 cGc/cAc 0 +SRP72 UCSF GRCh37 4 57335892 57335892 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 64 150 0 ENST00000342756.5:c.183C>T p.Phe61= p.F61= ENST00000342756 NM_006947.3 61 ttC/ttT 0 +SRRT UCSF GRCh37 7 100484763 100484763 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 84 138 0 ENST00000347433.4:c.1917C>T p.Arg639= p.R639= ENST00000347433 639 cgC/cgT 0 +SSBP2 UCSF GRCh37 5 80733256 80733256 + missense_variant Missense_Mutation SNP A A C NOVEL P10_Rec Untested WXS Illumina HiSeq 82 79 164 0 ENST00000320672.4:c.950T>G p.Ile317Ser p.I317S ENST00000320672 NM_001256732.1 317 aTt/aGt 0 +SSBP2 UCSF GRCh37 5 80809501 80809501 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 79 158 0 ENST00000320672.4:c.318C>T p.Asn106= p.N106= ENST00000320672 NM_001256732.1 106 aaC/aaT 0 +SSBP3 UCSF GRCh37 1 54704825 54704825 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 88 156 0 ENST00000371320.3:c.904C>T p.Pro302Ser p.P302S ENST00000371320 NM_145716.3 302 Ccg/Tcg 0 +SSH3 UCSF GRCh37 11 67075382 67075382 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 37 59 0 ENST00000308127.4:c.857G>A p.Ser286Asn p.S286N ENST00000308127 NM_017857.3 286 aGt/aAt 0 +SSH3 UCSF GRCh37 11 67075717 67075717 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 42 87 0 ENST00000308127.4:c.958C>T p.Leu320= p.L320= ENST00000308127 NM_017857.3 320 Ctg/Ttg 0 +SSPO UCSF GRCh37 7 149494363 149494363 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 54 126 0 ENST00000378016.2:n.6834C>T *2278* ENST00000378016 0 +SSPO UCSF GRCh37 7 149521558 149521558 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 19 27 47 0 ENST00000378016.2:n.13637C>T *4546* ENST00000378016 0 +SSPO UCSF GRCh37 7 149517757 149517757 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 8 16 0 ENST00000378016.2:n.12194G>A *4065* ENST00000378016 0 +SSPO UCSF GRCh37 7 149496924 149496924 + splice_region_variant,non_coding_transcript_exon_variant Splice_Region SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 38 36 70 1 ENST00000378016.2:n.6964A>G p.X2322_splice ENST00000378016 0 +SSPO UCSF GRCh37 7 149490472 149490472 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 12 25 0 ENST00000378016.2:n.5948G>A *1983* ENST00000378016 0 +ST7L UCSF GRCh37 1 113124626 113124626 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 104 228 0 ENST00000358039.4:c.1057G>A p.Ala353Thr p.A353T ENST00000358039 NM_138727.3 353 Gca/Aca 0 +STAB1 UCSF GRCh37 3 52539369 52539369 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 3 22 40 0 ENST00000321725.6:c.1553C>T p.Ala518Val p.A518V ENST00000321725 NM_015136.2 518 gCc/gTc 0 +STAB2 UCSF GRCh37 12 104136309 104136309 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 82 211 0 ENST00000388887.2:c.6008G>A p.Gly2003Glu p.G2003E ENST00000388887 NM_017564.9 2003 gGg/gAg 0 +STAB2 UCSF GRCh37 12 104134509 104134509 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 55 133 0 ENST00000388887.2:c.5856G>A p.Lys1952= p.K1952= ENST00000388887 NM_017564.9 1952 aaG/aaA 0 +STAB2 UCSF GRCh37 12 104144413 104144413 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 55 57 115 0 ENST00000388887.2:c.6495G>A p.Glu2165= p.E2165= ENST00000388887 NM_017564.9 2165 gaG/gaA 0 +STAG2 UCSF GRCh37 X 123197828 123197828 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 57 51 134 0 ENST00000218089.9:c.1952A>G p.Asp651Gly p.D651G ENST00000218089 NM_001042749.1 651 gAt/gGt 0 +STAG2 UCSF GRCh37 X 123197850 123197850 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 64 60 128 0 ENST00000218089.9:c.1974A>G p.Ile658Met p.I658M ENST00000218089 NM_001042749.1 658 atA/atG 0 +STAR UCSF GRCh37 8 38001867 38001867 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 9 26 0 ENST00000276449.4:c.782C>T p.Ser261Phe p.S261F ENST00000276449 NM_000349.2 261 tCc/tTc 0 +STAT3 UCSF GRCh37 17 40481593 40481593 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 135 109 190 0 ENST00000264657.5:c.1212C>T p.Leu404= p.L404= ENST00000264657 NM_139276.2 404 ctC/ctT 0 +STK10 UCSF GRCh37 5 171481694 171481694 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 68 105 0 ENST00000176763.5:c.2531C>T p.Ser844Phe p.S844F ENST00000176763 NM_005990.3 844 tCc/tTc 0 +STK32A UCSF GRCh37 5 146752788 146752788 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 125 96 201 0 ENST00000397936.3:c.834C>T p.Phe278= p.F278= ENST00000397936 NM_001112724.1 278 ttC/ttT 0 +STOX1 UCSF GRCh37 10 70646337 70646337 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 57 126 0 ENST00000298596.6:c.2785C>T p.His929Tyr p.H929Y ENST00000298596 NM_152709.4 929 Cac/Tac 0 +STXBP2 UCSF GRCh37 19 7707331 7707331 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 55 118 0 ENST00000221283.5:c.811C>T p.Leu271= p.L271= ENST00000221283 NM_006949.3 271 Ctg/Ttg 0 +STXBP5 UCSF GRCh37 6 147525712 147525712 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 17 13 33 0 ENST00000321680.6:c.44C>T p.Ala15Val p.A15V ENST00000321680 NM_001127715.2 15 gCc/gTc 0 +STXBP5L UCSF GRCh37 3 121132107 121132107 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 73 133 0 ENST00000273666.6:c.3123C>T p.Tyr1041= p.Y1041= ENST00000273666 NM_014980.2 1041 taC/taT 0 +STYK1 UCSF GRCh37 12 10772850 10772850 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 104 234 0 ENST00000075503.3:c.1162G>A p.Asp388Asn p.D388N ENST00000075503 NM_018423.2 388 Gat/Aat 0 +SUDS3 UCSF GRCh37 12 118823930 118823930 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 68 159 0 ENST00000543473.1:c.280G>A p.Glu94Lys p.E94K ENST00000543473 NM_022491.2 94 Gaa/Aaa 0 +SULT1A2 UCSF GRCh37 16 28604784 28604784 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 67 150 0 ENST00000395630.1:c.478G>A p.Glu160Lys p.E160K ENST00000395630 NM_177528.2 160 Gag/Aag 0 +SUN5 UCSF GRCh37 20 31571649 31571649 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 74 152 0 ENST00000356173.3:c.1091C>T p.Ala364Val p.A364V ENST00000356173 NM_080675.3 364 gCc/gTc 0 +SUSD1 UCSF GRCh37 9 114875083 114875083 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 107 38 137 0 ENST00000374270.3:c.952T>C p.Ser318Pro p.S318P ENST00000374270 NM_022486.3 318 Tca/Cca 0 +SV2A UCSF GRCh37 1 149878210 149878210 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 12 81 0 ENST00000369146.3:c.1877G>A p.Arg626Lys p.R626K ENST00000369146 NM_014849.4 626 aGa/aAa 0 +SVEP1 UCSF GRCh37 9 113238568 113238568 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 199 93 172 0 ENST00000401783.2:c.2515G>A p.Asp839Asn p.D839N ENST00000401783 NM_153366.3 839 Gac/Aac 0 +SVEP1 UCSF GRCh37 9 113169029 113169029 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 249 113 278 0 ENST00000401783.2:c.8851C>T p.Pro2951Ser p.P2951S ENST00000401783 NM_153366.3 2951 Cct/Tct 0 +SYCP1 UCSF GRCh37 1 115399279 115399279 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 43 100 0 ENST00000369522.3:c.193+1G>A p.X65_splice ENST00000369522 NM_003176.2 0 +SYK UCSF GRCh37 9 93607751 93607751 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 52 140 0 ENST00000375746.1:c.453G>A p.Lys151= p.K151= ENST00000375746 NM_001174167.1 151 aaG/aaA 0 +SYNE1 UCSF GRCh37 6 152674744 152674744 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 52 130 0 ENST00000367255.5:c.11062G>A p.Ala3688Thr p.A3688T ENST00000367255 NM_182961.3 3688 Gcc/Acc 0 +SYNE1 UCSF GRCh37 6 152605293 152605293 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 60 45 88 0 ENST00000367255.5:c.18027G>A p.Glu6009= p.E6009= ENST00000367255 NM_182961.3 6009 gaG/gaA 0 +SYNE1 UCSF GRCh37 6 152694193 152694193 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 141 140 228 0 ENST00000367255.5:c.9486C>T p.His3162= p.H3162= ENST00000367255 NM_182961.3 3162 caC/caT 0 +SYNE2 UCSF GRCh37 14 64460688 64460688 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 86 75 124 0 ENST00000358025.3:c.2781+1G>A p.X927_splice ENST00000358025 NM_182914.2 0 +SYNJ1 UCSF GRCh37 21 34060638 34060638 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 22 65 0 ENST00000433931.2:c.946G>A p.Ala316Thr p.A316T ENST00000433931 NM_003895.3 316 Gcc/Acc 0 +SYNPO UCSF GRCh37 5 149997948 149997948 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 9 25 0 ENST00000394243.1:c.19C>T p.Pro7Ser p.P7S ENST00000394243 NM_001166208.1 7 Cca/Tca 0 +SYNPO2 UCSF GRCh37 4 119952515 119952515 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 86 155 0 ENST00000307142.4:c.2585C>T p.Ser862Phe p.S862F ENST00000307142 NM_133477.2 862 tCc/tTc 0 +SYNPO2L UCSF GRCh37 10 75407132 75407132 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 66 111 0 ENST00000394810.2:c.2278G>A p.Glu760Lys p.E760K ENST00000394810 NM_001114133.1 760 Gag/Aag 0 +SYNRG UCSF GRCh37 17 35913924 35913924 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 84 173 0 ENST00000339208.6:c.1901C>T p.Ser634Leu p.S634L ENST00000339208 NM_001163544.1 634 tCa/tTa 0 +SYNRG UCSF GRCh37 17 35930963 35930963 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 83 205 0 ENST00000339208.6:c.1120C>T p.Pro374Ser p.P374S ENST00000339208 NM_001163544.1 374 Cct/Tct 0 +SYT10 UCSF GRCh37 12 33532825 33532825 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 71 175 0 ENST00000228567.3:c.1442G>A p.Trp481Ter p.W481* ENST00000228567 NM_198992.3 481 tGg/tAg 0 +SZT2 UCSF GRCh37 1 43897534 43897534 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 45 120 0 ENST00000562955.1:c.5065G>A p.Val1689Ile p.V1689I ENST00000562955 NM_015284.3 1689 Gta/Ata 0 +TAAR5 UCSF GRCh37 6 132910054 132910054 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 54 74 122 0 ENST00000258034.2:c.772G>A p.Val258Met p.V258M ENST00000258034 NM_003967.2 258 Gtg/Atg 0 +TACC3 UCSF GRCh37 4 1730443 1730443 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 40 66 0 ENST00000313288.4:c.1314G>A p.Arg438= p.R438= ENST00000313288 NM_006342.2 438 agG/agA 0 +TACR1 UCSF GRCh37 2 75425842 75425842 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 83 82 156 0 ENST00000305249.5:c.219C>T p.Asn73= p.N73= ENST00000305249 NM_001058.3 73 aaC/aaT 0 +TACR2 UCSF GRCh37 10 71176015 71176015 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 58 52 94 0 ENST00000373306.4:c.65G>A p.Gly22Asp p.G22D ENST00000373306 NM_001057.2 22 gGc/gAc 0 +TAF1L UCSF GRCh37 9 32633141 32633141 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 120 113 215 1 ENST00000242310.4:c.2437C>T p.Pro813Ser p.P813S ENST00000242310 NM_153809.2 813 Cct/Tct 0 +TAF3 UCSF GRCh37 10 8007315 8007315 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 156 82 170 0 ENST00000344293.5:c.1842G>A p.Glu614= p.E614= ENST00000344293 NM_031923.3 614 gaG/gaA 0 +TAF5 UCSF GRCh37 10 105145228 105145228 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 36 46 108 0 ENST00000369839.3:c.1810G>A p.Gly604Ser p.G604S ENST00000369839 NM_006951.3 604 Ggc/Agc 0 +TAGLN2 UCSF GRCh37 1 159889463 159889463 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 73 161 0 ENST00000368097.4:c.343G>A p.Asp115Asn p.D115N ENST00000368097 NM_003564.2 115 Gac/Aac 0 +TANC2 UCSF GRCh37 17 61489480 61489480 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0011 P10_Rec Untested WXS Illumina HiSeq 67 64 136 0 ENST00000424789.2:c.3665G>A p.Gly1222Glu p.G1222E ENST00000424789 NM_025185.3 1222 gGa/gAa 0 +TAPBP UCSF GRCh37 6 33281012 33281012 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 57 148 0 ENST00000426633.2:c.451C>T p.Leu151Phe p.L151F ENST00000426633 NM_172208.2 151 Ctc/Ttc 0 +TARSL2 UCSF GRCh37 15 102242566 102242566 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 94 179 0 ENST00000335968.3:c.1097G>A p.Gly366Asp p.G366D ENST00000335968 NM_152334.2 366 gGc/gAc 0 +TAS1R2 UCSF GRCh37 1 19186128 19186128 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 57 131 0 ENST00000375371.3:c.27C>T p.Ser9= p.S9= ENST00000375371 NM_152232.2 9 tcC/tcT 0 +TAS2R4 UCSF GRCh37 7 141479030 141479030 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 87 180 0 ENST00000247881.2:c.742G>A p.Val248Ile p.V248I ENST00000247881 NM_016944.1 248 Gtc/Atc 0 +TATDN2 UCSF GRCh37 3 10302232 10302232 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 88 166 0 ENST00000287652.4:c.826G>A p.Val276Ile p.V276I ENST00000287652 NM_014760.3 276 Gtt/Att 0 +TBC1D1 UCSF GRCh37 4 38134843 38134843 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 84 160 0 ENST00000261439.4:c.3271C>T p.Arg1091Cys p.R1091C ENST00000261439 NM_015173.3 1091 Cgc/Tgc 0 +TBC1D19 UCSF GRCh37 4 26737084 26737084 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 15 38 0 ENST00000264866.4:c.1092C>T p.Ile364= p.I364= ENST00000264866 NM_018317.2 364 atC/atT 0 +TBC1D24 UCSF GRCh37 16 2548319 2548319 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 16 13 34 0 ENST00000293970.5:c.1064C>T p.Ser355Phe p.S355F ENST00000293970 NM_001199107.1 355 tCc/tTc 0 +TBCEL UCSF GRCh37 11 120925837 120925837 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 75 155 0 ENST00000422003.2:c.532C>T p.Leu178= p.L178= ENST00000422003 NM_152715.3 178 Cta/Tta 0 +TBL1XR1 UCSF GRCh37 3 176763952 176763952 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 28 89 0 ENST00000430069.1:c.890C>T p.Thr297Ile p.T297I ENST00000430069 297 aCt/aTt 0 +TBX2 UCSF GRCh37 17 59485626 59485626 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 32 57 0 ENST00000240328.3:c.1898G>A p.Ser633Asn p.S633N ENST00000240328 NM_005994.3 633 aGc/aAc 0 +TBX4 UCSF GRCh37 17 59560522 59560522 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 71 119 0 ENST00000240335.1:c.1283G>A p.Ser428Asn p.S428N ENST00000240335 NM_018488.2 428 aGc/aAc 0 +TBXAS1 UCSF GRCh37 7 139661920 139661920 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 67 130 0 ENST00000416849.2:c.1163C>T p.Ala388Val p.A388V ENST00000416849 NM_001166253.1 388 gCt/gTt 0 +TC2N UCSF GRCh37 14 92264214 92264214 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 54 134 0 ENST00000435962.2:c.770G>A p.Gly257Glu p.G257E ENST00000435962 NM_001128596.1 257 gGa/gAa 0 +TCEB3 UCSF GRCh37 1 24077927 24077927 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 71 137 0 ENST00000418390.2:c.910G>A p.Glu304Lys p.E304K ENST00000418390 NM_003198.2 304 Gag/Aag 0 +TCF23 UCSF GRCh37 2 27375694 27375694 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 72 152 0 ENST00000296096.5:c.604C>T p.Leu202Phe p.L202F ENST00000296096 NM_175769.2 202 Ctt/Ttt 0 +TCTN3 UCSF GRCh37 10 97447086 97447086 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 42 90 0 ENST00000371217.5:c.654C>T p.Phe218= p.F218= ENST00000371217 218 ttC/ttT 0 +TCTN3 UCSF GRCh37 10 97453525 97453525 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 20 12 27 0 ENST00000371217.5:c.132C>T p.Gly44= p.G44= ENST00000371217 44 ggC/ggT 0 +TDRD1 UCSF GRCh37 10 115963291 115963291 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 84 178 0 ENST00000251864.2:c.946G>A p.Gly316Arg p.G316R ENST00000251864 NM_198795.1 316 Ggg/Agg 0 +TDRD5 UCSF GRCh37 1 179620034 179620034 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 81 223 0 ENST00000444136.1:c.1833C>T p.Phe611= p.F611= ENST00000444136 NM_001199089.1 611 ttC/ttT 0 +TDRD7 UCSF GRCh37 9 100235884 100235884 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 126 73 178 0 ENST00000355295.4:c.2055G>A p.Lys685= p.K685= ENST00000355295 NM_014290.2 685 aaG/aaA 0 +TDRD9 UCSF GRCh37 14 104431696 104431696 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 57 155 1 ENST00000409874.4:c.447C>T p.Ser149= p.S149= ENST00000409874 NM_153046.2 149 tcC/tcT 0 +TDRD9 UCSF GRCh37 14 104465049 104465049 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 119 216 0 ENST00000409874.4:c.1467C>T p.Ser489= p.S489= ENST00000409874 NM_153046.2 489 agC/agT 0 +TECPR2 UCSF GRCh37 14 102900784 102900784 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 64 160 0 ENST00000359520.7:c.1630C>T p.Pro544Ser p.P544S ENST00000359520 NM_014844.3 544 Ccc/Tcc 0 +TECPR2 UCSF GRCh37 14 102916172 102916172 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 46 130 1 ENST00000359520.7:c.3282G>A p.Lys1094= p.K1094= ENST00000359520 NM_014844.3 1094 aaG/aaA 0 +TEF UCSF GRCh37 22 41783452 41783452 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 4 69 102 0 ENST00000266304.4:c.255G>A p.Lys85= p.K85= ENST00000266304 NM_003216.3 85 aaG/aaA 0 +TENC1 UCSF GRCh37 12 53453352 53453352 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 34 54 0 ENST00000314276.3:c.1957C>T p.Leu653Phe p.L653F ENST00000314276 NM_015319.2 653 Ctc/Ttc 0 +TENC1 UCSF GRCh37 12 53453006 53453006 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 28 33 0 ENST00000314276.3:c.1611C>T p.Ser537= p.S537= ENST00000314276 NM_015319.2 537 tcC/tcT 0 +TEP1 UCSF GRCh37 14 20851479 20851479 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 42 65 0 ENST00000262715.5:c.3901G>A p.Ala1301Thr p.A1301T ENST00000262715 NM_007110.4 1301 Gca/Aca 0 +TERF1 UCSF GRCh37 8 73921345 73921345 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 18 45 0 ENST00000276603.5:c.224C>T p.Ala75Val p.A75V ENST00000276603 NM_017489.2 75 gCc/gTc 0 +TET2 UCSF GRCh37 4 106190870 106190870 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 55 51 114 0 ENST00000380013.4:c.4148G>A p.Arg1383Lys p.R1383K ENST00000380013 NM_001127208.2 1383 aGa/aAa 0 +TET3 UCSF GRCh37 2 74274381 74274381 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 44 119 0 ENST00000409262.3:c.932C>T p.Pro311Leu p.P311L ENST00000409262 NM_144993.1 311 cCc/cTc 0 +TEX10 UCSF GRCh37 9 103109180 103109180 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 195 100 191 0 ENST00000374902.4:c.689G>A p.Arg230Lys p.R230K ENST00000374902 NM_017746.3 230 aGa/aAa 0 +TEX15 UCSF GRCh37 8 30705592 30705592 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 71 50 149 0 ENST00000256246.2:c.942C>T p.Thr314= p.T314= ENST00000256246 NM_031271.3 314 acC/acT 0 +TEX15 UCSF GRCh37 8 30706429 30706429 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 105 97 202 0 ENST00000256246.2:c.105C>T p.Asn35= p.N35= ENST00000256246 NM_031271.3 35 aaC/aaT 0 +TFE3 UCSF GRCh37 X 48895560 48895560 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 16 12 40 0 ENST00000315869.7:c.860C>T p.Thr287Ile p.T287I ENST00000315869 NM_006521.4 287 aCc/aTc 0 +TFEB UCSF GRCh37 6 41653940 41653940 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 74 133 0 ENST00000230323.4:c.839C>T p.Ala280Val p.A280V ENST00000230323 NM_007162.2 280 gCc/gTc 0 +TG UCSF GRCh37 8 134144104 134144104 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 204 73 119 0 ENST00000220616.4:c.7911C>T p.Tyr2637= p.Y2637= ENST00000220616 NM_003235.4 2637 taC/taT 0 +TG UCSF GRCh37 8 133919027 133919027 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 133 38 61 0 ENST00000220616.4:c.3729G>A p.Gln1243= p.Q1243= ENST00000220616 NM_003235.4 1243 caG/caA 0 +TGFA UCSF GRCh37 2 70683575 70683575 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 11 26 0 ENST00000295400.6:c.261C>T p.Leu87= p.L87= ENST00000295400 NM_001099691.2 87 ctC/ctT 0 +TGFB1 UCSF GRCh37 19 41854289 41854289 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 84 165 0 ENST00000221930.5:c.427G>A p.Ala143Thr p.A143T ENST00000221930 NM_000660.4 143 Gcg/Acg 0 +TGFBR3 UCSF GRCh37 1 92262859 92262859 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 78 187 0 ENST00000212355.4:c.231C>T p.Gly77= p.G77= ENST00000212355 NM_001195683.1 77 ggC/ggT 0 +TGIF2LX UCSF GRCh37 X 89177490 89177490 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 67 152 0 ENST00000561129.2:c.406C>T p.Gln136Ter p.Q136* ENST00000561129 136 Cag/Tag 0 +TGM3 UCSF GRCh37 20 2290834 2290834 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 114 75 184 0 ENST00000381458.5:c.192C>T p.Pro64= p.P64= ENST00000381458 NM_003245.3 64 ccC/ccT 0 +THADA UCSF GRCh37 2 43655362 43655362 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 82 186 1 ENST00000405006.4:c.3935G>A p.Gly1312Glu p.G1312E ENST00000405006 NM_001083953.1 1312 gGa/gAa 0 +THBS2 UCSF GRCh37 6 169637393 169637393 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 32 81 0 ENST00000366787.3:c.1349C>T p.Ser450Phe p.S450F ENST00000366787 NM_003247.2 450 tCt/tTt 0 +THEG UCSF GRCh37 19 375960 375960 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 31 51 0 ENST00000342640.4:c.11G>A p.Ser4Asn p.S4N ENST00000342640 NM_016585.4 4 aGc/aAc 0 +THOC2 UCSF GRCh37 X 122759802 122759802 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 66 164 0 ENST00000245838.8:c.3018G>A p.Gln1006= p.Q1006= ENST00000245838 NM_001081550.1 1006 caG/caA 0 +THSD7A UCSF GRCh37 7 11468604 11468604 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 136 127 204 0 ENST00000423059.4:c.3213G>A p.Arg1071= p.R1071= ENST00000423059 NM_015204.2 1071 agG/agA 0 +THSD7B UCSF GRCh37 2 138169344 138169344 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 149 129 247 0 ENST00000272643.3:c.2861C>T p.Ala954Val p.A954V ENST00000272643 954 gCa/gTa 0 +THUMPD1 UCSF GRCh37 16 20750362 20750362 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 78 146 0 ENST00000381337.2:c.263G>A p.Ser88Asn p.S88N ENST00000381337 NM_017736.3 88 aGt/aAt 0 +TIA1 UCSF GRCh37 2 70443408 70443408 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 28 26 51 0 ENST00000433529.2:c.696G>A p.Gln232= p.Q232= ENST00000433529 NM_022173.2 232 caG/caA 0 +TIAM1 UCSF GRCh37 21 32525434 32525434 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 67 173 0 ENST00000286827.3:c.3190G>A p.Glu1064Lys p.E1064K ENST00000286827 NM_003253.2 1064 Gag/Aag 0 +TIGD5 UCSF GRCh37 8 144680339 144680339 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 4 9 0 ENST00000504548.2:c.266G>A p.Arg89His p.R89H ENST00000504548 NM_032862.4 89 cGc/cAc 0 +TIMELESS UCSF GRCh37 12 56826196 56826196 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 71 75 153 0 ENST00000553532.1:c.644G>A p.Ser215Asn p.S215N ENST00000553532 215 aGc/aAc 0 +TIMELESS UCSF GRCh37 12 56811993 56811993 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 124 94 182 0 ENST00000553532.1:c.3379A>G p.Lys1127Glu p.K1127E ENST00000553532 1127 Aaa/Gaa 0 +TJP2 UCSF GRCh37 9 71869199 71869199 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 154 80 138 0 ENST00000539225.1:c.3575C>T p.Ala1192Val p.A1192V ENST00000539225 NM_001170416.1 1192 gCc/gTc 0 +TJP2 UCSF GRCh37 9 71849405 71849405 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 45 137 0 ENST00000539225.1:c.1815C>T p.Tyr605= p.Y605= ENST00000539225 NM_001170416.1 605 taC/taT 0 +TKTL2 UCSF GRCh37 4 164393404 164393404 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 78 159 0 ENST00000280605.3:c.1483C>T p.Gln495Ter p.Q495* ENST00000280605 NM_032136.4 495 Cag/Tag 0 +TLK1 UCSF GRCh37 2 171884884 171884884 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 45 123 0 ENST00000431350.2:c.1201G>A p.Glu401Lys p.E401K ENST00000431350 401 Gaa/Aaa 0 +TLK1 UCSF GRCh37 2 171871453 171871453 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 73 78 188 0 ENST00000431350.2:c.1242G>A p.Glu414= p.E414= ENST00000431350 414 gaG/gaA 0 +TLL1 UCSF GRCh37 4 166981289 166981289 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 40 146 0 ENST00000061240.2:c.1956C>T p.Thr652= p.T652= ENST00000061240 NM_012464.4 652 acC/acT 0 +TLL2 UCSF GRCh37 10 98157046 98157046 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0015 P10_Rec Untested WXS Illumina HiSeq 54 43 81 0 ENST00000357947.3:c.1281C>T p.Gly427= p.G427= ENST00000357947 NM_012465.3 427 ggC/ggT 0 +TLN1 UCSF GRCh37 9 35725306 35725306 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 41 77 0 ENST00000314888.9:c.143G>A p.Gly48Glu p.G48E ENST00000314888 NM_006289.3 48 gGg/gAg 0 +TLN2 UCSF GRCh37 15 63008649 63008649 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 37 91 0 ENST00000561311.1:c.2754C>T p.Asn918= p.N918= ENST00000561311 918 aaC/aaT 0 +TLN2 UCSF GRCh37 15 63088326 63088326 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 40 98 0 ENST00000561311.1:c.5884G>A p.Val1962Ile p.V1962I ENST00000561311 1962 Gtc/Atc 0 +TM7SF3 UCSF GRCh37 12 27148236 27148236 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 92 65 135 0 ENST00000343028.4:c.624G>A p.Glu208= p.E208= ENST00000343028 NM_016551.2 208 gaG/gaA 0 +TMC2 UCSF GRCh37 20 2593935 2593935 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 33 51 120 0 ENST00000358864.1:c.1839C>T p.Asn613= p.N613= ENST00000358864 NM_080751.2 613 aaC/aaT 0 +TMC6 UCSF GRCh37 17 76118775 76118775 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 15 41 0 ENST00000590602.1:c.1138G>A p.Ala380Thr p.A380T ENST00000590602 380 Gcc/Acc 0 +TMC6 UCSF GRCh37 17 76116781 76116781 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 125 88 193 0 ENST00000590602.1:c.1668C>T p.Asp556= p.D556= ENST00000590602 556 gaC/gaT 0 +TMEM121 UCSF GRCh37 14 105995323 105995323 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 22 13 14 0 ENST00000392519.2:c.152G>A p.Cys51Tyr p.C51Y ENST00000392519 NM_025268.2 51 tGc/tAc 0 +TMEM131 UCSF GRCh37 2 98408904 98408904 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 27 17 40 0 ENST00000186436.5:c.4089C>T p.Ser1363= p.S1363= ENST00000186436 NM_015348.1 1363 tcC/tcT 0 +TMEM132C UCSF GRCh37 12 129190605 129190605 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 18 23 32 0 ENST00000435159.2:c.3092C>T p.Ser1031Phe p.S1031F ENST00000435159 NM_001136103.2 1031 tCc/tTc 0 +TMEM139 UCSF GRCh37 7 142983697 142983697 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 91 163 0 ENST00000359333.3:c.426G>A p.Arg142= p.R142= ENST00000359333 NM_001282876.1 142 agG/agA 0 +TMEM156 UCSF GRCh37 4 38995377 38995377 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 101 90 184 0 ENST00000381938.3:c.600C>T p.His200= p.H200= ENST00000381938 NM_024943.1 200 caC/caT 0 +TMEM201 UCSF GRCh37 1 9661350 9661350 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 50 84 0 ENST00000340381.6:c.794C>T p.Thr265Ile p.T265I ENST00000340381 NM_001130924.2 265 aCc/aTc 0 +TMEM205 UCSF GRCh37 19 11453739 11453739 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 49 37 71 0 ENST00000354882.5:c.322C>T p.Pro108Ser p.P108S ENST00000354882 108 Ccc/Tcc 0 +TMEM214 UCSF GRCh37 2 27261943 27261943 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 38 90 0 ENST00000238788.9:c.1436G>A p.Arg479Gln p.R479Q ENST00000238788 NM_017727.4 479 cGg/cAg 0 +TMEM232 UCSF GRCh37 5 109963542 109963542 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 37 84 0 ENST00000455884.2:c.541C>T p.Leu181= p.L181= ENST00000455884 181 Ctg/Ttg 0 +TMEM234 UCSF GRCh37 1 32682944 32682944 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 56 100 0 ENST00000309777.6:c.244C>T p.Leu82= p.L82= ENST00000309777 NM_019118.3 82 Ctg/Ttg 0 +TMEM237 UCSF GRCh37 2 202496808 202496808 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 126 97 216 0 ENST00000409883.2:c.519C>T p.Ser173= p.S173= ENST00000409883 NM_001044385.2 173 agC/agT 0 +TMEM38A UCSF GRCh37 19 16772124 16772124 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 10 10 0 ENST00000187762.2:c.96C>T p.Val32= p.V32= ENST00000187762 NM_024074.1 32 gtC/gtT 0 +TMEM47 UCSF GRCh37 X 34657462 34657462 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 44 77 0 ENST00000275954.3:c.269C>T p.Ala90Val p.A90V ENST00000275954 NM_031442.3 90 gCc/gTc 0 +TMEM59L UCSF GRCh37 19 18728993 18728993 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 27 96 0 ENST00000600490.1:c.693G>A p.Arg231= p.R231= ENST00000600490 231 agG/agA 0 +TMEM74 UCSF GRCh37 8 109796546 109796546 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 187 70 134 0 ENST00000297459.3:c.782G>A p.Arg261His p.R261H ENST00000297459 NM_153015.1 261 cGt/cAt 0 +TMPRSS15 UCSF GRCh37 21 19713814 19713814 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 79 177 0 ENST00000284885.3:c.1480G>A p.Asp494Asn p.D494N ENST00000284885 NM_002772.2 494 Gac/Aac 0 +TMTC3 UCSF GRCh37 12 88582692 88582692 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 58 128 0 ENST00000266712.6:c.1505C>T p.Ser502Phe p.S502F ENST00000266712 NM_181783.3 502 tCt/tTt 0 +TMUB1 UCSF GRCh37 7 150778822 150778822 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 14 9 15 0 ENST00000392818.3:c.555G>A p.Gly185= p.G185= ENST00000392818 NM_031434.3 185 ggG/ggA 0 +TNC UCSF GRCh37 9 117808778 117808778 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 231 96 219 0 ENST00000350763.4:c.5036G>A p.Gly1679Asp p.G1679D ENST00000350763 NM_002160.3 1679 gGt/gAt 0 +TNC UCSF GRCh37 9 117826119 117826119 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 151 65 159 0 ENST00000350763.4:c.3716C>T p.Thr1239Ile p.T1239I ENST00000350763 NM_002160.3 1239 aCt/aTt 0 +TNC UCSF GRCh37 9 117848837 117848837 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 163 74 124 0 ENST00000350763.4:c.1173G>A p.Arg391= p.R391= ENST00000350763 NM_002160.3 391 cgG/cgA 0 +TNFRSF11A UCSF GRCh37 18 60036604 60036604 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 53 49 98 0 ENST00000586569.1:c.1454G>A p.Ser485Asn p.S485N ENST00000586569 NM_001278268.1 485 aGc/aAc 0 +TNFRSF11B UCSF GRCh37 8 119945463 119945463 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 292 79 206 0 ENST00000297350.4:c.107C>T p.Ser36Phe p.S36F ENST00000297350 NM_002546.3 36 tCt/tTt 0 +TNFRSF1B UCSF GRCh37 1 12266822 12266822 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 43 93 0 ENST00000376259.3:c.1131C>T p.Thr377= p.T377= ENST00000376259 NM_001066.2 377 acC/acT 0 +TNIP1 UCSF GRCh37 5 150443200 150443200 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 57 111 0 ENST00000389378.2:c.245C>T p.Ser82Phe p.S82F ENST00000389378 NM_001252385.1 82 tCc/tTc 0 +TNK1 UCSF GRCh37 17 7286633 7286633 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 85 169 0 ENST00000576812.1:c.228C>T p.Val76= p.V76= ENST00000576812 NM_001251902.1 76 gtC/gtT 0 +TNK2 UCSF GRCh37 3 195594767 195594767 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 15 9 17 0 ENST00000381916.2:c.2591C>T p.Pro864Leu p.P864L ENST00000381916 NM_001010938.1 864 cCt/cTt 0 +TNKS1BP1 UCSF GRCh37 11 57069696 57069696 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 41 64 0 ENST00000532437.1:c.4686C>T p.Asp1562= p.D1562= ENST00000532437 1562 gaC/gaT 0 +TNNT2 UCSF GRCh37 1 201331124 201331124 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 86 64 152 0 ENST00000509001.1:c.606G>A p.Gln202= p.Q202= ENST00000509001 NM_001276347.1 202 caG/caA 0 +TNRC6A UCSF GRCh37 16 24788512 24788512 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 91 166 0 ENST00000395799.3:c.422G>A p.Arg141His p.R141H ENST00000395799 NM_014494.2 141 cGc/cAc 0 +TNRC6A UCSF GRCh37 16 24802403 24802403 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 38 122 0 ENST00000395799.3:c.2440G>A p.Val814Ile p.V814I ENST00000395799 NM_014494.2 814 Gtc/Atc 0 +TNS4 UCSF GRCh37 17 38636093 38636093 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 26 29 33 0 ENST00000254051.6:c.1743C>T p.Gly581= p.G581= ENST00000254051 NM_032865.5 581 ggC/ggT 0 +TOP3A UCSF GRCh37 17 18208448 18208448 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 62 126 0 ENST00000321105.5:c.477G>A p.Glu159= p.E159= ENST00000321105 NM_004618.3 159 gaG/gaA 0 +TOPBP1 UCSF GRCh37 3 133320145 133320145 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 79 59 139 0 ENST00000260810.5:c.4518G>A p.Lys1506= p.K1506= ENST00000260810 NM_007027.3 1506 aaG/aaA 0 +TOR2A UCSF GRCh37 9 130495707 130495707 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 89 49 94 0 ENST00000373284.5:c.550G>A p.Val184Ile p.V184I ENST00000373284 NM_001085347.2 184 Gta/Ata 0 +TOX UCSF GRCh37 8 59728200 59728200 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 53 44 106 0 ENST00000361421.1:c.1089C>T p.Ser363= p.S363= ENST00000361421 NM_014729.2 363 agC/agT 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 1 82 83 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TP53BP1 UCSF GRCh37 15 43769868 43769868 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 68 171 0 ENST00000382044.4:c.878G>A p.Gly293Glu p.G293E ENST00000382044 NM_001141980.1 293 gGa/gAa 0 +TP53BP2 UCSF GRCh37 1 223983936 223983936 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 110 91 150 0 ENST00000343537.7:c.2305G>A p.Glu769Lys p.E769K ENST00000343537 NM_001031685.2 769 Gag/Aag 0 +TP63 UCSF GRCh37 3 189455553 189455553 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 72 65 166 0 ENST00000264731.3:c.87C>T p.Phe29= p.F29= ENST00000264731 NM_003722.4 29 ttC/ttT 0 +TP73 UCSF GRCh37 1 3645890 3645890 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 35 57 0 ENST00000378295.4:c.1075-1G>A p.X359_splice ENST00000378295 NM_005427.3 0 +TPCN2 UCSF GRCh37 11 68840393 68840393 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 39 86 0 ENST00000294309.3:c.1154C>T p.Ser385Phe p.S385F ENST00000294309 NM_139075.3 385 tCc/tTc 0 +TPRN UCSF GRCh37 9 140086761 140086761 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0039 P10_Rec Untested WXS Illumina HiSeq 74 26 61 0 ENST00000409012.4:c.2023G>A p.Ala675Thr p.A675T ENST00000409012 NM_001128228.2 675 Gcg/Acg 0 +TPRN UCSF GRCh37 9 140087087 140087087 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 43 95 0 ENST00000409012.4:c.1782G>A p.Glu594= p.E594= ENST00000409012 NM_001128228.2 594 gaG/gaA 0 +TRABD UCSF GRCh37 22 50635990 50635990 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 46 76 0 ENST00000303434.4:c.644G>A p.Gly215Asp p.G215D ENST00000303434 NM_025204.2 215 gGc/gAc 0 +TRAF3IP3 UCSF GRCh37 1 209933650 209933650 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 25 39 0 ENST00000367024.1:c.266C>T p.Pro89Leu p.P89L ENST00000367024 89 cCc/cTc 0 +TRANK1 UCSF GRCh37 3 36873744 36873744 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 137 200 0 ENST00000429976.2:c.7198C>T p.Pro2400Ser p.P2400S ENST00000429976 2400 Cca/Tca 0 +TRAPPC6B UCSF GRCh37 14 39628700 39628700 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 43 134 0 ENST00000330149.5:c.136G>A p.Gly46Arg p.G46R ENST00000330149 NM_001079537.1 46 Gga/Aga 0 +TRAPPC9 UCSF GRCh37 8 141461167 141461167 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 294 71 138 0 ENST00000389328.4:c.600G>A p.Gln200= p.Q200= ENST00000389328 NM_031466.5 200 caG/caA 0 +TRDMT1 UCSF GRCh37 10 17195563 17195563 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 52 114 0 ENST00000377799.3:c.1018C>T p.Leu340= p.L340= ENST00000377799 NM_004412.5 340 Ctg/Ttg 0 +TREM1 UCSF GRCh37 6 41248854 41248854 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 59 42 114 0 ENST00000244709.4:c.444C>T p.Thr148= p.T148= ENST00000244709 NM_018643.3 148 acC/acT 0 +TREM2 UCSF GRCh37 6 41127546 41127546 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 25 83 0 ENST00000373113.3:c.466G>A p.Glu156Lys p.E156K ENST00000373113 NM_018965.3 156 Gag/Aag 0 +TREML1 UCSF GRCh37 6 41117489 41117489 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 106 80 135 0 ENST00000426005.2:c.789C>T p.Ser263= p.S263= ENST00000426005 NM_178174.3 263 tcC/tcT 0 +TRHDE UCSF GRCh37 12 72667167 72667167 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 45 87 0 ENST00000261180.4:c.609C>T p.Val203= p.V203= ENST00000261180 NM_013381.2 203 gtC/gtT 0 +TRIM15 UCSF GRCh37 6 30131780 30131780 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 35 81 0 ENST00000376694.4:c.319G>A p.Glu107Lys p.E107K ENST00000376694 NM_033229.2 107 Gag/Aag 0 +TRIM16L UCSF GRCh37 17 18630996 18630996 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 73 80 161 0 ENST00000449552.2:c.126G>A p.Arg42= p.R42= ENST00000449552 42 agG/agA 0 +TRIM33 UCSF GRCh37 1 114952805 114952805 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 70 142 0 ENST00000358465.2:c.2194+1G>A p.X732_splice ENST00000358465 NM_015906.3 0 +TRIM42 UCSF GRCh37 3 140407071 140407071 + missense_variant Missense_Mutation SNP T T G NOVEL P10_Rec Untested WXS Illumina HiSeq 85 65 156 0 ENST00000286349.3:c.1547T>G p.Ile516Ser p.I516S ENST00000286349 NM_152616.4 516 aTt/aGt 0 +TRIM50 UCSF GRCh37 7 72727137 72727137 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 9 14 0 ENST00000333149.2:c.1244G>A p.Gly415Glu p.G415E ENST00000333149 NM_001281450.1 415 gGg/gAg 0 +TRIM55 UCSF GRCh37 8 67040642 67040642 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 65 174 0 ENST00000315962.4:c.272G>A p.Gly91Glu p.G91E ENST00000315962 NM_184085.1 91 gGg/gAg 0 +TRIM7 UCSF GRCh37 5 180622331 180622331 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 25 16 31 0 ENST00000274773.7:c.1371C>T p.His457= p.H457= ENST00000274773 NM_203293.2 457 caC/caT 0 +TRIML1 UCSF GRCh37 4 189060893 189060893 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 79 154 0 ENST00000332517.3:c.181G>A p.Glu61Lys p.E61K ENST00000332517 NM_178556.3 61 Gag/Aag 0 +TRIOBP UCSF GRCh37 22 38106452 38106452 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 26 35 0 ENST00000406386.3:c.133G>A p.Gly45Ser p.G45S ENST00000406386 NM_001039141.2 45 Ggt/Agt 0 +TRIOBP UCSF GRCh37 22 38119897 38119897 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 97 201 0 ENST00000406386.3:c.1334G>A p.Arg445Lys p.R445K ENST00000406386 NM_001039141.2 445 aGa/aAa 0 +TRMT11 UCSF GRCh37 6 126319699 126319699 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 54 134 0 ENST00000334379.5:c.391C>T p.Leu131Phe p.L131F ENST00000334379 NM_001031712.2 131 Ctt/Ttt 0 +TRNAU1AP UCSF GRCh37 1 28891228 28891228 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 82 182 0 ENST00000373830.3:c.292C>T p.Leu98Phe p.L98F ENST00000373830 NM_017846.4 98 Ctc/Ttc 0 +TRO UCSF GRCh37 X 54949889 54949889 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 17 26 48 0 ENST00000173898.7:c.924G>A p.Arg308= p.R308= ENST00000173898 NM_001039705.2 308 agG/agA 0 +TRPC3 UCSF GRCh37 4 122803559 122803559 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 69 20 124 0 ENST00000379645.3:c.2573G>A p.Arg858Gln p.R858Q ENST00000379645 NM_001130698.1 858 cGg/cAg 0 +TRPC5 UCSF GRCh37 X 111195523 111195523 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 83 65 151 0 ENST00000262839.2:c.126G>A p.Lys42= p.K42= ENST00000262839 NM_012471.2 42 aaG/aaA 0 +TRPM2 UCSF GRCh37 21 45784113 45784113 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 61 145 0 ENST00000397928.1:c.371C>T p.Thr124Ile p.T124I ENST00000397928 NM_003307.3 124 aCc/aTc 0 +TRPM2 UCSF GRCh37 21 45826605 45826605 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 8 10 22 0 ENST00000397928.1:c.2919C>T p.His973= p.H973= ENST00000397928 NM_003307.3 973 caC/caT 0 +TRPM2 UCSF GRCh37 21 45825063 45825063 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 67 57 123 0 ENST00000397928.1:c.2577G>A p.Lys859= p.K859= ENST00000397928 NM_003307.3 859 aaG/aaA 0 +TRPM3 UCSF GRCh37 9 73150932 73150932 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 232 116 188 0 ENST00000377110.3:c.5061C>T p.Ser1687= p.S1687= ENST00000377110 1687 agC/agT 0 +TRPM3 UCSF GRCh37 9 73167824 73167824 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 192 94 200 0 ENST00000377110.3:c.3474C>T p.Phe1158= p.F1158= ENST00000377110 1158 ttC/ttT 0 +TRPM4 UCSF GRCh37 19 49714491 49714491 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 6 14 10 0 ENST00000252826.5:c.3605G>A p.Gly1202Asp p.G1202D ENST00000252826 NM_017636.3 1202 gGt/gAt 0 +TRPM4 UCSF GRCh37 19 49675322 49675322 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 77 52 128 0 ENST00000252826.5:c.1107G>A p.Gly369= p.G369= ENST00000252826 NM_017636.3 369 ggG/ggA 0 +TRPM6 UCSF GRCh37 9 77353524 77353524 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 54 119 0 ENST00000360774.1:c.5575C>T p.Leu1859= p.L1859= ENST00000360774 NM_017662.4 1859 Ctg/Ttg 0 +TRPS1 UCSF GRCh37 8 116426543 116426543 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 157 55 131 0 ENST00000395715.3:c.3593C>T p.Thr1198Met p.T1198M ENST00000395715 NM_014112.2 1198 aCg/aTg 0 +TRPV6 UCSF GRCh37 7 142572668 142572668 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 73 133 0 ENST00000359396.3:c.1275C>T p.Phe425= p.F425= ENST00000359396 NM_018646.4 425 ttC/ttT 0 +TRUB2 UCSF GRCh37 9 131071985 131071985 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 41 95 0 ENST00000372890.4:c.840G>A p.Gln280= p.Q280= ENST00000372890 NM_015679.1 280 caG/caA 0 +TSC1 UCSF GRCh37 9 135781026 135781026 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 173 80 182 0 ENST00000298552.3:c.1939G>A p.Glu647Lys p.E647K ENST00000298552 NM_001162426.1 647 Gaa/Aaa 0 +TSEN34 UCSF GRCh37 19 54695758 54695758 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 66 46 88 0 ENST00000396383.1:c.430G>A p.Ala144Thr p.A144T ENST00000396383 144 Gct/Act 0 +TSGA10 UCSF GRCh37 2 99635071 99635071 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 31 59 0 ENST00000393483.3:c.1850G>A p.Arg617Lys p.R617K ENST00000393483 NM_025244.2 617 aGa/aAa 0 +TSGA10IP UCSF GRCh37 11 65714692 65714692 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 44 23 47 0 ENST00000532620.1:n.627C>T *209* ENST00000532620 0 +TSHZ3 UCSF GRCh37 19 31768300 31768300 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 64 129 0 ENST00000240587.4:c.2399G>A p.Gly800Asp p.G800D ENST00000240587 NM_020856.2 800 gGc/gAc 0 +TSNARE1 UCSF GRCh37 8 143356193 143356193 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 8 15 0 ENST00000307180.3:c.1395C>T p.Ser465= p.S465= ENST00000307180 NM_145003.3 465 tcC/tcT 0 +TSNARE1 UCSF GRCh37 8 143427177 143427177 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 157 34 58 0 ENST00000307180.3:c.165C>T p.Arg55= p.R55= ENST00000307180 NM_145003.3 55 cgC/cgT 0 +TSPAN10 UCSF GRCh37 17 79612306 79612306 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 38 39 91 0 ENST00000328585.4:c.325G>A p.Gly109Arg p.G109R ENST00000328585 NM_031945.3 109 Gga/Aga 0 +TSPAN12 UCSF GRCh37 7 120450610 120450610 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 39 127 0 ENST00000222747.3:c.375G>A p.Trp125Ter p.W125* ENST00000222747 NM_012338.3 125 tgG/tgA 0 +TSPAN16 UCSF GRCh37 19 11422816 11422816 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 23 57 0 ENST00000316737.1:c.605G>A p.Gly202Asp p.G202D ENST00000316737 NM_012466.2 202 gGc/gAc 0 +TSSK1B UCSF GRCh37 5 112770079 112770079 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 83 160 0 ENST00000390666.3:c.458C>T p.Ser153Phe p.S153F ENST00000390666 NM_032028.3 153 tCc/tTc 0 +TSSK3 UCSF GRCh37 1 32829748 32829748 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 74 74 143 0 ENST00000373534.3:c.698G>A p.Ser233Asn p.S233N ENST00000373534 NM_052841.3 233 aGc/aAc 0 +TSTA3 UCSF GRCh37 8 144695091 144695091 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 14 20 0 ENST00000425753.2:c.955G>A p.Ala319Thr p.A319T ENST00000425753 NM_003313.3 319 Gcc/Acc 0 +TSTA3 UCSF GRCh37 8 144698311 144698311 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 324 75 155 0 ENST00000425753.2:c.226C>T p.Leu76= p.L76= ENST00000425753 NM_003313.3 76 Ctg/Ttg 0 +TSTD2 UCSF GRCh37 9 100373856 100373856 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 172 79 160 0 ENST00000341170.4:c.729G>A p.Lys243= p.K243= ENST00000341170 NM_139246.4 243 aaG/aaA 0 +TTBK2 UCSF GRCh37 15 43038251 43038251 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 58 144 0 ENST00000267890.6:c.3477C>T p.Ser1159= p.S1159= ENST00000267890 NM_173500.3 1159 tcC/tcT 0 +TTC17 UCSF GRCh37 11 43429077 43429077 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 2 44 110 0 ENST00000039989.4:c.2014C>T p.Leu672Phe p.L672F ENST00000039989 NM_018259.5 672 Ctt/Ttt 0 +TTC18 UCSF GRCh37 10 75053137 75053137 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 80 68 131 0 ENST00000310715.3:c.1864G>A p.Asp622Asn p.D622N ENST00000310715 NM_145170.3 622 Gat/Aat 0 +TTC24 UCSF GRCh37 1 156555537 156555537 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 113 123 204 0 ENST00000368236.3:c.1489C>T p.His497Tyr p.H497Y ENST00000368236 NM_001105669.2 497 Cac/Tac 0 +TTC26 UCSF GRCh37 7 138865855 138865855 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 77 59 105 0 ENST00000464848.1:c.1330C>T p.Pro444Ser p.P444S ENST00000464848 NM_001287513.1 444 Cca/Tca 0 +TTC28 UCSF GRCh37 22 28389370 28389370 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 10 25 0 ENST00000397906.2:c.5381C>T p.Pro1794Leu p.P1794L ENST00000397906 NM_001145418.1 1794 cCc/cTc 0 +TTC28 UCSF GRCh37 22 28494902 28494902 + splice_donor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 52 50 88 0 ENST00000397906.2:c.3547+1G>A p.X1183_splice ENST00000397906 NM_001145418.1 0 +TTC3 UCSF GRCh37 21 38538141 38538141 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 114 203 0 ENST00000399017.2:c.3625C>T p.Pro1209Ser p.P1209S ENST00000399017 NM_003316.3 1209 Cca/Tca 0 +TTC38 UCSF GRCh37 22 46679926 46679926 + synonymous_variant Silent SNP G G A snp132_rs5768270 P10_Rec Untested WXS Illumina HiSeq 9 81 203 0 ENST00000381031.3:c.792G>A p.Glu264= p.E264= ENST00000381031 NM_017931.2 264 gaG/gaA 0 +TTC7B UCSF GRCh37 14 91211201 91211201 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 58 149 0 ENST00000328459.6:c.511G>A p.Asp171Asn p.D171N ENST00000328459 NM_001010854.1 171 Gat/Aat 0 +TTLL2 UCSF GRCh37 6 167753706 167753706 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 63 102 0 ENST00000239587.5:c.318G>A p.Arg106= p.R106= ENST00000239587 NM_031949.4 106 agG/agA 0 +TTLL5 UCSF GRCh37 14 76165563 76165563 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 35 83 0 ENST00000298832.9:c.535G>A p.Val179Ile p.V179I ENST00000298832 NM_015072.4 179 Gta/Ata 0 +TTLL7 UCSF GRCh37 1 84335694 84335694 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 38 59 119 0 ENST00000260505.8:c.2615G>A p.Gly872Glu p.G872E ENST00000260505 NM_024686.4 872 gGa/gAa 0 +TTN UCSF GRCh37 2 179403718 179403718 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 91 64 169 0 ENST00000589042.1:c.98944G>A p.Glu32982Lys p.E32982K ENST00000589042 NM_001267550.1 32982 Gag/Aag 0 +TTN UCSF GRCh37 2 179616401 179616401 + intron_variant Intron SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 85 81 197 0 ENST00000589042.1:c.11311+1450G>A *3771* ENST00000589042 NM_001267550.1 0 +TTN UCSF GRCh37 2 179469033 179469033 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 68 58 128 0 ENST00000589042.1:c.54382-1G>A p.X18128_splice ENST00000589042 NM_001267550.1 0 +TTN UCSF GRCh37 2 179629420 179629420 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 71 174 0 ENST00000589042.1:c.9822G>A p.Lys3274= p.K3274= ENST00000589042 NM_001267550.1 3274 aaG/aaA 0 +TUBD1 UCSF GRCh37 17 57963589 57963589 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 76 50 112 0 ENST00000325752.3:c.175C>T p.Pro59Ser p.P59S ENST00000325752 NM_016261.3 59 Cca/Tca 0 +TUBGCP3 UCSF GRCh37 13 113176698 113176698 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 7 63 150 0 ENST00000261965.3:c.1681G>A p.Ala561Thr p.A561T ENST00000261965 NM_006322.4 561 Gca/Aca 0 +TULP3 UCSF GRCh37 12 3046829 3046829 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 11 55 0 ENST00000397132.2:c.957G>A p.Arg319= p.R319= ENST00000397132 NM_001160408.1 319 agG/agA 0 +TUSC3 UCSF GRCh37 8 15398061 15398061 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 18 41 0 ENST00000503731.1:c.122G>A p.Gly41Glu p.G41E ENST00000503731 NM_006765.3 41 gGa/gAa 0 +TWF2 UCSF GRCh37 3 52263952 52263952 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 3 36 59 0 ENST00000305533.5:c.744C>T p.Asp248= p.D248= ENST00000305533 NM_007284.3 248 gaC/gaT 0 +TXLNG UCSF GRCh37 X 16847817 16847817 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 67 159 0 ENST00000380122.5:c.788C>T p.Ala263Val p.A263V ENST00000380122 NM_018360.2 263 gCc/gTc 0 +TXNDC17 UCSF GRCh37 17 6546334 6546334 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 54 128 0 ENST00000250101.5:c.367G>A p.Asp123Asn p.D123N ENST00000250101 NM_032731.3 123 Gat/Aat 0 +TXNDC2 UCSF GRCh37 18 9887505 9887505 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 123 118 231 0 ENST00000306084.6:c.1029C>T p.Asp343= p.D343= ENST00000306084 NM_001098529.1 343 gaC/gaT 0 +UBE3C UCSF GRCh37 7 156967682 156967682 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 104 110 217 0 ENST00000348165.5:c.412C>T p.Leu138Phe p.L138F ENST00000348165 NM_014671.2 138 Ctt/Ttt 0 +UBR2 UCSF GRCh37 6 42658896 42658896 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 84 163 0 ENST00000372899.1:c.5253C>T p.Asp1751= p.D1751= ENST00000372899 NM_015255.2 1751 gaC/gaT 0 +UBR3 UCSF GRCh37 2 170806358 170806358 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 146 112 233 0 ENST00000418381.1:c.3328C>T p.Pro1110Ser p.P1110S ENST00000418381 NM_172070.3 1110 Cct/Tct 0 +UBR5 UCSF GRCh37 8 103323703 103323703 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 195 61 153 0 ENST00000520539.1:c.2440G>A p.Asp814Asn p.D814N ENST00000520539 NM_015902.5 814 Gat/Aat 0 +UBXN11 UCSF GRCh37 1 26609419 26609419 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 40 80 0 ENST00000374222.1:c.1087C>T p.Pro363Ser p.P363S ENST00000374222 363 Cca/Tca 0 +UBXN2B UCSF GRCh37 8 59346977 59346977 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 24 32 65 0 ENST00000399598.2:c.447G>A p.Trp149Ter p.W149* ENST00000399598 NM_001077619.1 149 tgG/tgA 0 +UCK1 UCSF GRCh37 9 134404345 134404345 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 41 44 0 ENST00000372211.3:c.604G>A p.Glu202Lys p.E202K ENST00000372211 202 Gag/Aag 0 +UGCG UCSF GRCh37 9 114676906 114676906 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 152 53 172 0 ENST00000374279.3:c.120G>A p.Lys40= p.K40= ENST00000374279 NM_003358.1 40 aaG/aaA 0 +UGT1A4 UCSF GRCh37 2 234627943 234627943 + synonymous_variant Silent SNP G G A snp132_rs45467894 P10_Rec Untested WXS Illumina HiSeq 226 36 222 0 ENST00000373409.3:c.477G>A p.Ala159= p.A159= ENST00000373409 NM_007120.2 159 gcG/gcA 0 +UGT1A7 UCSF GRCh37 2 234590941 234590942 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 0 ENST00000373426.3:c.364dup p.Ser122PhefsTer8 p.S122Ffs*8 ENST00000373426 NM_019077.2 120 ttt/tTtt 0 +UGT2A1 UCSF GRCh37 4 70512715 70512715 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 58 154 0 ENST00000503640.1:c.648C>T p.Tyr216= p.Y216= ENST00000503640 NM_006798.3 216 taC/taT 0 +UGT2B10 UCSF GRCh37 4 69886008 69886008 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 146 111 259 0 ENST00000505092.1:n.125G>A *42* ENST00000505092 0 +UHRF2 UCSF GRCh37 9 6413522 6413522 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 5 13 43 0 ENST00000276893.5:c.32C>T p.Ser11Phe p.S11F ENST00000276893 NM_152896.2 11 tCc/tTc 0 +ULK2 UCSF GRCh37 17 19689373 19689373 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 40 58 124 0 ENST00000395544.4:c.2128C>T p.Leu710= p.L710= ENST00000395544 NM_014683.3 710 Ctg/Ttg 0 +UMOD UCSF GRCh37 16 20357622 20357622 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 45 37 135 0 ENST00000570689.1:c.1008G>A p.Gly336= p.G336= ENST00000570689 336 ggG/ggA 0 +UNC45A UCSF GRCh37 15 91479194 91479194 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 23 81 0 ENST00000418476.2:c.232G>A p.Glu78Lys p.E78K ENST00000418476 NM_018671.3 78 Gaa/Aaa 0 +UNC45A UCSF GRCh37 15 91486252 91486252 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 63 59 131 0 ENST00000418476.2:c.967G>A p.Val323Met p.V323M ENST00000418476 NM_018671.3 323 Gtg/Atg 0 +UNC5D UCSF GRCh37 8 35647908 35647908 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 74 68 150 0 ENST00000404895.2:c.2689C>T p.Pro897Ser p.P897S ENST00000404895 NM_080872.2 897 Cca/Tca 0 +UNC79 UCSF GRCh37 14 94121687 94121687 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 119 72 191 0 ENST00000256339.4:c.5976C>T p.Leu1992= p.L1992= ENST00000256339 NM_020818.3 1992 ctC/ctT 0 +UNKL UCSF GRCh37 16 1463919 1463919 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 8 9 0 ENST00000389221.4:c.215C>T p.Thr72Ile p.T72I ENST00000389221 NM_001193388.3 72 aCc/aTc 0 +UPF2 UCSF GRCh37 10 12071404 12071404 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 203 79 209 0 ENST00000356352.2:c.485G>A p.Ser162Asn p.S162N ENST00000356352 162 aGc/aAc 0 +UROC1 UCSF GRCh37 3 126211339 126211339 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 21 33 0 ENST00000383579.3:c.1710G>A p.Arg570= p.R570= ENST00000383579 NM_001165974.1 570 agG/agA 0 +USH1G UCSF GRCh37 17 72916727 72916727 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 41 70 0 ENST00000319642.1:c.204C>T p.Pro68= p.P68= ENST00000319642 NM_173477.2 68 ccC/ccT 0 +USP14 UCSF GRCh37 18 199201 199201 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 67 164 0 ENST00000261601.7:c.762-1G>A p.X254_splice ENST00000261601 NM_005151.3 0 +USP16 UCSF GRCh37 21 30421082 30421082 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 47 96 0 ENST00000334352.4:c.2012G>A p.Gly671Asp p.G671D ENST00000334352 NM_001032410.1 671 gGt/gAt 0 +USP29 UCSF GRCh37 19 57641558 57641558 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 118 98 222 0 ENST00000254181.4:c.1515G>A p.Arg505= p.R505= ENST00000254181 NM_020903.2 505 agG/agA 0 +USP31 UCSF GRCh37 16 23083470 23083470 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 61 39 93 0 ENST00000219689.7:c.2384G>A p.Gly795Asp p.G795D ENST00000219689 NM_020718.3 795 gGc/gAc 0 +USP31 UCSF GRCh37 16 23093858 23093858 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 48 43 100 0 ENST00000219689.7:c.1851G>A p.Trp617Ter p.W617* ENST00000219689 NM_020718.3 617 tgG/tgA 0 +USP37 UCSF GRCh37 2 219399332 219399332 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 72 119 0 ENST00000258399.3:c.778G>A p.Gly260Arg p.G260R ENST00000258399 NM_020935.2 260 Ggg/Agg 0 +USP42 UCSF GRCh37 7 6193961 6193961 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 13 22 0 ENST00000306177.5:c.2776G>A p.Asp926Asn p.D926N ENST00000306177 NM_032172.2 926 Gac/Aac 0 +USP49 UCSF GRCh37 6 41773902 41773902 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 54 127 0 ENST00000373006.1:c.820C>T p.Leu274Phe p.L274F ENST00000373006 NM_018561.3 274 Ctc/Ttc 0 +USP53 UCSF GRCh37 4 120192956 120192956 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 102 100 201 0 ENST00000450251.1:c.1941G>A p.Lys647= p.K647= ENST00000450251 647 aaG/aaA 0 +USP6 UCSF GRCh37 17 5042941 5042941 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 57 57 105 0 ENST00000574788.1:c.1470C>T p.Thr490= p.T490= ENST00000574788 490 acC/acT 0 +USP6 UCSF GRCh37 17 5049340 5049340 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 85 190 0 ENST00000574788.1:c.2190C>T p.Thr730= p.T730= ENST00000574788 730 acC/acT 0 +USP6NL UCSF GRCh37 10 11531176 11531176 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 188 97 232 0 ENST00000277575.5:c.640C>T p.Leu214Phe p.L214F ENST00000277575 NM_001080491.2 214 Ctc/Ttc 0 +USP7 UCSF GRCh37 16 9017133 9017133 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 67 164 0 ENST00000344836.4:c.322G>A p.Asp108Asn p.D108N ENST00000344836 NM_003470.2 108 Gac/Aac 0 +USP9X UCSF GRCh37 X 41031163 41031163 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 83 67 172 0 ENST00000324545.8:c.3100C>T p.Pro1034Ser p.P1034S ENST00000324545 NM_001039590.2 1034 Cca/Tca 0 +UST UCSF GRCh37 6 149340293 149340293 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 68 171 0 ENST00000367463.4:c.700C>T p.Leu234Phe p.L234F ENST00000367463 NM_005715.2 234 Ctt/Ttt 0 +UTP23 UCSF GRCh37 8 117783700 117783700 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 221 68 168 0 ENST00000309822.2:c.369G>A p.Gln123= p.Q123= ENST00000309822 NM_032334.2 123 caG/caA 0 +UTP6 UCSF GRCh37 17 30207669 30207669 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 90 227 0 ENST00000261708.4:c.890C>T p.Ala297Val p.A297V ENST00000261708 NM_018428.2 297 gCc/gTc 0 +UTRN UCSF GRCh37 6 145157578 145157578 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 73 147 0 ENST00000367545.3:c.9966G>A p.Arg3322= p.R3322= ENST00000367545 NM_007124.2 3322 agG/agA 0 +VANGL1 UCSF GRCh37 1 116226592 116226592 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 45 110 0 ENST00000355485.2:c.974C>T p.Ser325Phe p.S325F ENST00000355485 NM_001172411.1 325 tCc/tTc 0 +VARS2 UCSF GRCh37 6 30890299 30890299 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 70 124 0 ENST00000541562.1:c.2095C>T p.Pro699Ser p.P699S ENST00000541562 NM_001167734.1 699 Cca/Tca 0 +VAV1 UCSF GRCh37 19 6825417 6825417 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 18 20 40 0 ENST00000602142.1:c.827G>A p.Arg276Lys p.R276K ENST00000602142 NM_005428.3 276 aGg/aAg 0 +VAV2 UCSF GRCh37 9 136648680 136648680 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 27 50 0 ENST00000371850.3:c.1668G>A p.Lys556= p.K556= ENST00000371850 NM_001134398.1 556 aaG/aaA 0 +VAX2 UCSF GRCh37 2 71160028 71160028 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 27 29 59 0 ENST00000234392.2:c.567C>T p.Gly189= p.G189= ENST00000234392 NM_012476.2 189 ggC/ggT 0 +VCAM1 UCSF GRCh37 1 101194751 101194751 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 92 197 0 ENST00000294728.2:c.1017C>T p.Gly339= p.G339= ENST00000294728 NM_001078.3 339 ggC/ggT 0 +VCAN UCSF GRCh37 5 82817933 82817933 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 103 110 209 0 ENST00000265077.3:c.3808G>A p.Glu1270Lys p.E1270K ENST00000265077 NM_004385.4 1270 Gaa/Aaa 0 +VCAN UCSF GRCh37 5 82808139 82808139 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 31 33 56 0 ENST00000265077.3:c.966G>A p.Val322= p.V322= ENST00000265077 NM_004385.4 322 gtG/gtA 0 +VCAN UCSF GRCh37 5 82836478 82836478 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 70 58 160 0 ENST00000265077.3:c.7656G>A p.Lys2552= p.K2552= ENST00000265077 NM_004385.4 2552 aaG/aaA 0 +VCX UCSF GRCh37 X 7811579 7811579 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 166 24 326 0 ENST00000381059.3:c.143G>A p.Gly48Glu p.G48E ENST00000381059 NM_013452.2 48 gGg/gAg 0 +VEGFB UCSF GRCh37 11 64004961 64004961 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 25 23 39 0 ENST00000309422.2:c.480C>T p.Pro160= p.P160= ENST00000309422 NM_003377.4 160 ccC/ccT 0 +VGLL4 UCSF GRCh37 3 11606380 11606380 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 21 23 0 ENST00000430365.2:c.386C>T p.Ser129Phe p.S129F ENST00000430365 NM_001128219.1 129 tCc/tTc 0 +VHL UCSF GRCh37 3 10183713 10183713 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 12 5 13 0 ENST00000256474.2:c.182C>T p.Pro61Leu p.P61L ENST00000256474 NM_000551.3 61 cCc/cTc 0 +VIL1 UCSF GRCh37 2 219290394 219290394 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 51 47 100 0 ENST00000248444.5:c.207C>T p.Asp69= p.D69= ENST00000248444 NM_007127.2 69 gaC/gaT 0 +VOPP1 UCSF GRCh37 7 55588814 55588814 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 49 52 105 0 ENST00000285279.5:c.64G>A p.Ala22Thr p.A22T ENST00000285279 NM_030796.3 22 Gcc/Acc 0 +VPRBP UCSF GRCh37 3 51457206 51457206 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 117 191 0 ENST00000423656.1:c.1931G>A p.Arg644Lys p.R644K ENST00000423656 644 aGg/aAg 0 +VPS13A UCSF GRCh37 9 79897163 79897163 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 137 81 145 0 ENST00000360280.3:c.3091G>A p.Asp1031Asn p.D1031N ENST00000360280 NM_033305.2 1031 Gac/Aac 0 +VPS13B UCSF GRCh37 8 100887721 100887721 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 295 106 158 0 ENST00000358544.2:c.11896C>T p.His3966Tyr p.H3966Y ENST00000358544 NM_017890.4 3966 Cac/Tac 0 +VPS13B UCSF GRCh37 8 100880671 100880671 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 92 28 56 0 ENST00000358544.2:c.11445G>A p.Glu3815= p.E3815= ENST00000358544 NM_017890.4 3815 gaG/gaA 0 +VPS13C UCSF GRCh37 15 62223314 62223314 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 90 176 0 ENST00000261517.5:c.6013G>A p.Glu2005Lys p.E2005K ENST00000261517 NM_020821.2 2005 Gaa/Aaa 0 +VPS13C UCSF GRCh37 15 62302748 62302748 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 101 83 153 0 ENST00000261517.5:c.934G>A p.Glu312Lys p.E312K ENST00000261517 NM_020821.2 312 Gaa/Aaa 0 +VPS13D UCSF GRCh37 1 12336919 12336919 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 103 96 178 0 ENST00000358136.3:c.3274C>T p.Pro1092Ser p.P1092S ENST00000358136 NM_015378.2 1092 Cca/Tca 0 +VPS13D UCSF GRCh37 1 12364596 12364596 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 46 39 80 0 ENST00000358136.3:c.6250C>T p.Pro2084Ser p.P2084S ENST00000358136 NM_015378.2 2084 Ccc/Tcc 0 +VPS13D UCSF GRCh37 1 12343695 12343695 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 97 67 144 0 ENST00000358136.3:c.5536C>T p.Leu1846= p.L1846= ENST00000358136 NM_015378.2 1846 Ctg/Ttg 0 +VPS18 UCSF GRCh37 15 41192761 41192761 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 135 92 98 0 ENST00000220509.5:c.1745C>T p.Ala582Val p.A582V ENST00000220509 NM_020857.2 582 gCc/gTc 0 +VPS33A UCSF GRCh37 12 122735630 122735630 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 56 38 99 0 ENST00000267199.4:c.500G>A p.Gly167Asp p.G167D ENST00000267199 NM_022916.4 167 gGt/gAt 0 +VPS33B UCSF GRCh37 15 91548327 91548327 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 49 100 0 ENST00000333371.3:c.1128C>T p.Ile376= p.I376= ENST00000333371 NM_018668.3 376 atC/atT 0 +VPS35 UCSF GRCh37 16 46695702 46695702 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 107 91 148 0 ENST00000299138.7:c.2139C>T p.Pro713= p.P713= ENST00000299138 NM_018206.4 713 ccC/ccT 0 +VTI1B UCSF GRCh37 14 68120170 68120170 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.00092 P10_Rec Untested WXS Illumina HiSeq 42 33 76 0 ENST00000554659.1:c.586C>T p.Arg196Cys p.R196C ENST00000554659 NM_006370.2 196 Cgt/Tgt 0 +VWA5A UCSF GRCh37 11 123989046 123989046 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 67 130 0 ENST00000456829.2:c.397C>T p.Leu133= p.L133= ENST00000456829 NM_001130142.1 133 Ctg/Ttg 0 +VWA5B2 UCSF GRCh37 3 183955045 183955045 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 41 46 81 0 ENST00000426955.2:c.1565C>T p.Pro522Leu p.P522L ENST00000426955 NM_138345.1 522 cCt/cTt 0 +VWCE UCSF GRCh37 11 61048580 61048580 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 21 14 26 0 ENST00000335613.5:c.915G>A p.Gly305= p.G305= ENST00000335613 NM_152718.2 305 ggG/ggA 0 +VWDE UCSF GRCh37 7 12381735 12381735 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 27 66 0 ENST00000275358.3:c.4220C>T p.Pro1407Leu p.P1407L ENST00000275358 NM_001135924.1 1407 cCa/cTa 0 +VWDE UCSF GRCh37 7 12428924 12428924 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 58 58 112 0 ENST00000275358.3:c.304C>T p.Pro102Ser p.P102S ENST00000275358 NM_001135924.1 102 Cca/Tca 0 +VWDE UCSF GRCh37 7 12410335 12410335 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 45 143 0 ENST00000275358.3:c.1743G>A p.Gly581= p.G581= ENST00000275358 NM_001135924.1 581 ggG/ggA 0 +VWF UCSF GRCh37 12 6125351 6125351 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 75 50 151 0 ENST00000261405.5:c.5359G>A p.Gly1787Ser p.G1787S ENST00000261405 NM_000552.3 1787 Ggt/Agt 0 +VWF UCSF GRCh37 12 6101071 6101071 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 43 46 79 0 ENST00000261405.5:c.6712C>T p.Pro2238Ser p.P2238S ENST00000261405 NM_000552.3 2238 Cct/Tct 0 +WAPAL UCSF GRCh37 10 88206137 88206137 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 87 74 139 0 ENST00000298767.5:c.3184C>T p.Pro1062Ser p.P1062S ENST00000298767 NM_015045.2 1062 Ccc/Tcc 0 +WARS UCSF GRCh37 14 100820200 100820200 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 56 54 83 0 ENST00000355338.2:c.549C>T p.Leu183= p.L183= ENST00000355338 NM_173701.1 183 ctC/ctT 0 +WASL UCSF GRCh37 7 123332789 123332789 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 50 65 79 0 ENST00000223023.4:c.959C>T p.Ala320Val p.A320V ENST00000223023 NM_003941.3 320 gCt/gTt 0 +WBSCR27 UCSF GRCh37 7 73256395 73256395 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 30 30 49 1 ENST00000297873.4:c.76G>A p.Ala26Thr p.A26T ENST00000297873 NM_152559.2 26 Gcc/Acc 0 +WDFY4 UCSF GRCh37 10 50184901 50184901 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 36 23 39 0 ENST00000325239.5:c.9168C>T p.Pro3056= p.P3056= ENST00000325239 NM_020945.1 3056 ccC/ccT 0 +WDR1 UCSF GRCh37 4 10086084 10086084 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 76 87 146 0 ENST00000499869.2:c.1022G>A p.Ser341Asn p.S341N ENST00000499869 341 aGc/aAc 0 +WDR1 UCSF GRCh37 4 10084717 10084717 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 50 45 80 0 ENST00000499869.2:c.1125G>A p.Glu375= p.E375= ENST00000499869 375 gaG/gaA 0 +WDR19 UCSF GRCh37 4 39217716 39217716 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 133 206 0 ENST00000399820.3:c.1135G>A p.Glu379Lys p.E379K ENST00000399820 NM_025132.3 379 Gag/Aag 0 +WDR41 UCSF GRCh37 5 76754933 76754933 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 85 89 162 0 ENST00000296679.4:c.365C>T p.Thr122Ile p.T122I ENST00000296679 NM_018268.2 122 aCt/aTt 0 +WDR52 UCSF GRCh37 3 113022845 113022845 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 91 206 0 ENST00000393845.2:c.4995G>A p.Lys1665= p.K1665= ENST00000393845 NM_001164496.1 1665 aaG/aaA 0 +WDR60 UCSF GRCh37 7 158672454 158672454 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 68 180 0 ENST00000407559.3:c.653C>T p.Pro218Leu p.P218L ENST00000407559 NM_018051.4 218 cCc/cTc 0 +WDR64 UCSF GRCh37 1 241842826 241842826 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 117 107 213 0 ENST00000366552.2:c.523C>T p.Leu175= p.L175= ENST00000366552 NM_144625.4 175 Ctg/Ttg 0 +WDR64 UCSF GRCh37 1 241901791 241901791 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 42 106 0 ENST00000366552.2:c.1291G>A p.Gly431Arg p.G431R ENST00000366552 NM_144625.4 431 Gga/Aga 0 +WDR67 UCSF GRCh37 8 124109547 124109547 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 249 71 176 0 ENST00000287380.1:c.697G>A p.Gly233Ser p.G233S ENST00000287380 NM_145647.3 233 Ggc/Agc 0 +WDR78 UCSF GRCh37 1 67293571 67293571 + missense_variant Missense_Mutation SNP C C T snp132_rs78356162 P10_Rec Untested WXS Illumina HiSeq 100 56 222 0 ENST00000371026.3:c.2036G>A p.Gly679Asp p.G679D ENST00000371026 NM_024763.4 679 gGc/gAc 0 +WDR87 UCSF GRCh37 19 38375629 38375629 + synonymous_variant Silent SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 76 51 144 0 ENST00000303868.5:c.8565T>C p.Pro2855= p.P2855= ENST00000303868 NM_031951.3 2855 ccT/ccC 0 +WDR90 UCSF GRCh37 16 708958 708958 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 70 70 90 0 ENST00000293879.4:c.2958C>T p.Val986= p.V986= ENST00000293879 986 gtC/gtT 0 +WDR93 UCSF GRCh37 15 90280885 90280885 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 72 64 145 0 ENST00000268130.7:c.1690G>A p.Gly564Arg p.G564R ENST00000268130 NM_020212.1 564 Gga/Aga 0 +WDYHV1 UCSF GRCh37 8 124453573 124453573 + missense_variant Missense_Mutation SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 70 24 45 0 ENST00000287387.2:c.536T>C p.Ile179Thr p.I179T ENST00000287387 NM_018024.1 179 aTc/aCc 0 +WFDC8 UCSF GRCh37 20 44190858 44190858 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 40 47 92 0 ENST00000357199.4:c.27G>A p.Gly9= p.G9= ENST00000357199 NM_181510.2 9 ggG/ggA 0 +WFS1 UCSF GRCh37 4 6303446 6303446 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 75 147 0 ENST00000226760.1:c.1924G>A p.Ala642Thr p.A642T ENST00000226760 NM_001145853.1 642 Gcc/Acc 0 +WHSC2 UCSF GRCh37 4 1993350 1993350 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 90 69 152 0 ENST00000382882.3:c.336G>A p.Pro112= p.P112= ENST00000382882 112 ccG/ccA 0 +WIPF3 UCSF GRCh37 7 29874428 29874428 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 31 31 64 0 ENST00000409290.1:c.88C>T p.Pro30Ser p.P30S ENST00000409290 NM_001080529.2 30 Ccg/Tcg 0 +WIPI1 UCSF GRCh37 17 66426297 66426297 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 60 95 0 ENST00000262139.5:c.805C>T p.Pro269Ser p.P269S ENST00000262139 NM_017983.5 269 Cca/Tca 0 +WISP2 UCSF GRCh37 20 43348583 43348583 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 23 17 30 0 ENST00000372868.2:c.106C>T p.Pro36Ser p.P36S ENST00000372868 36 Cct/Tct 0 +WISP3 UCSF GRCh37 6 112386099 112386099 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 123 100 212 0 ENST00000361714.1:c.542G>A p.Ser181Asn p.S181N ENST00000361714 181 aGt/aAt 0 +WIZ UCSF GRCh37 19 15558993 15558993 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 69 61 114 0 ENST00000263381.7:c.126C>T p.Gly42= p.G42= ENST00000263381 NM_021241.2 42 ggC/ggT 0 +WNK4 UCSF GRCh37 17 40939296 40939296 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 32 33 66 0 ENST00000246914.5:c.1477G>A p.Val493Met p.V493M ENST00000246914 NM_032387.4 493 Gtg/Atg 0 +WWOX UCSF GRCh37 16 78148914 78148914 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 100 68 179 0 ENST00000566780.1:c.272C>T p.Ala91Val p.A91V ENST00000566780 NM_016373.2 91 gCg/gTg 0 +XCL2 UCSF GRCh37 1 168510241 168510241 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 49 155 0 ENST00000367819.2:c.294G>A p.Lys98= p.K98= ENST00000367819 NM_003175.3 98 aaG/aaA 0 +XIRP1 UCSF GRCh37 3 39225432 39225432 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 1 27 39 0 ENST00000340369.3:c.5505C>T p.Cys1835= p.C1835= ENST00000340369 NM_194293.2 1835 tgC/tgT 0 +XIRP2 UCSF GRCh37 2 168104383 168104383 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 88 64 159 0 ENST00000409195.1:c.6481C>T p.Pro2161Ser p.P2161S ENST00000409195 NM_152381.5 2161 Ccc/Tcc 0 +XIRP2 UCSF GRCh37 2 168106448 168106448 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 120 84 201 0 ENST00000409195.1:c.8546C>T p.Ala2849Val p.A2849V ENST00000409195 NM_152381.5 2849 gCa/gTa 0 +XKR6 UCSF GRCh37 8 10755681 10755681 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 49 100 0 ENST00000416569.2:c.1707G>A p.Gly569= p.G569= ENST00000416569 NM_173683.3 569 ggG/ggA 0 +XPO6 UCSF GRCh37 16 28133067 28133067 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 47 66 99 0 ENST00000304658.5:c.1783C>T p.Leu595= p.L595= ENST00000304658 NM_015171.3 595 Ctg/Ttg 0 +XPO6 UCSF GRCh37 16 28187408 28187408 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 61 52 107 0 ENST00000304658.5:c.216C>T p.Ile72= p.I72= ENST00000304658 NM_015171.3 72 atC/atT 0 +XPO7 UCSF GRCh37 8 21840150 21840150 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 90 173 0 ENST00000252512.9:c.1105-1G>A p.X369_splice ENST00000252512 NM_015024.4 0 +XRCC5 UCSF GRCh37 2 217024854 217024854 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 82 57 128 0 ENST00000392133.3:c.1734C>T p.Val578= p.V578= ENST00000392133 578 gtC/gtT 0 +XRN2 UCSF GRCh37 20 21306968 21306968 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 67 69 125 0 ENST00000377191.3:c.127C>T p.Pro43Ser p.P43S ENST00000377191 NM_012255.3 43 Cca/Tca 0 +YEATS2 UCSF GRCh37 3 183524881 183524881 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 29 29 78 0 ENST00000305135.5:c.4011+1G>A p.X1337_splice ENST00000305135 NM_018023.4 0 +YIPF1 UCSF GRCh37 1 54332585 54332585 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 51 124 0 ENST00000072644.1:c.494C>T p.Ala165Val p.A165V ENST00000072644 NM_018982.4 165 gCt/gTt 0 +YIPF7 UCSF GRCh37 4 44626798 44626798 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 35 28 48 0 ENST00000332990.5:c.500C>T p.Ala167Val p.A167V ENST00000332990 NM_182592.2 167 gCa/gTa 0 +YLPM1 UCSF GRCh37 14 75248373 75248373 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 93 58 126 0 ENST00000325680.7:c.1627C>T p.Pro543Ser p.P543S ENST00000325680 NM_019589.2 543 Cca/Tca 0 +YTHDC2 UCSF GRCh37 5 112868676 112868676 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 61 147 0 ENST00000161863.4:c.776G>A p.Arg259Lys p.R259K ENST00000161863 NM_022828.3 259 aGa/aAa 0 +YTHDF1 UCSF GRCh37 20 61834707 61834707 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.014,1000g2011may_all_0.0485,snp132_rs115419512 P10_Rec Untested WXS Illumina HiSeq 51 52 75 0 ENST00000370339.3:c.585C>T p.Val195= p.V195= ENST00000370339 NM_017798.3 195 gtC/gtT 0 +YTHDF2 UCSF GRCh37 1 29069104 29069104 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 107 130 199 0 ENST00000373812.3:c.322C>T p.Pro108Ser p.P108S ENST00000373812 NM_016258.2 108 Cca/Tca 0 +ZBBX UCSF GRCh37 3 167086299 167086299 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 63 146 0 ENST00000455345.2:c.132G>A p.Lys44= p.K44= ENST00000455345 44 aaG/aaA 0 +ZBED4 UCSF GRCh37 22 50278966 50278966 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 12 124 193 0 ENST00000216268.5:c.1656G>A p.Met552Ile p.M552I ENST00000216268 NM_014838.2 552 atG/atA 0 +ZBTB44 UCSF GRCh37 11 130131626 130131626 + missense_variant Missense_Mutation SNP A A G NOVEL P10_Rec Untested WXS Illumina HiSeq 129 93 206 0 ENST00000525842.1:c.143T>C p.Val48Ala p.V48A ENST00000525842 NM_014155.4 48 gTa/gCa 0 +ZC3H11A UCSF GRCh37 1 203819029 203819029 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 78 70 146 0 ENST00000545588.1:c.1814C>T p.Thr605Ile p.T605I ENST00000545588 NM_001271675.1 605 aCa/aTa 0 +ZC3H12B UCSF GRCh37 X 64721891 64721891 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 78 150 0 ENST00000338957.4:c.1313C>T p.Pro438Leu p.P438L ENST00000338957 NM_001010888.3 438 cCc/cTc 0 +ZC3H12D UCSF GRCh37 6 149795470 149795470 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 19 18 65 0 ENST00000409806.3:c.210C>T p.Ala70= p.A70= ENST00000409806 70 gcC/gcT 0 +ZC3H18 UCSF GRCh37 16 88666340 88666340 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 78 60 118 0 ENST00000301011.5:c.1072G>A p.Asp358Asn p.D358N ENST00000301011 NM_144604.3 358 Gat/Aat 0 +ZC3H4 UCSF GRCh37 19 47570075 47570075 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 14 7 21 0 ENST00000253048.5:c.3450C>T p.Asp1150= p.D1150= ENST00000253048 NM_015168.1 1150 gaC/gaT 0 +ZCCHC17 UCSF GRCh37 1 31819541 31819541 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 64 53 119 0 ENST00000373714.1:c.372C>T p.Thr124= p.T124= ENST00000373714 NM_001282570.1 124 acC/acT 0 +ZCCHC4 UCSF GRCh37 4 25334924 25334924 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 60 156 0 ENST00000302874.4:c.449C>T p.Ser150Phe p.S150F ENST00000302874 NM_024936.2 150 tCc/tTc 0 +ZCCHC7 UCSF GRCh37 9 37357113 37357113 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 115 58 152 0 ENST00000336755.5:c.1480C>T p.Pro494Ser p.P494S ENST00000336755 NM_032226.2 494 Ccc/Tcc 0 +ZDBF2 UCSF GRCh37 2 207172904 207172904 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 143 118 242 0 ENST00000374423.3:c.3652G>A p.Val1218Ile p.V1218I ENST00000374423 NM_020923.1 1218 Gtt/Att 0 +ZDBF2 UCSF GRCh37 2 207146624 207146624 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 81 64 140 0 ENST00000374423.3:c.51C>T p.Asn17= p.N17= ENST00000374423 NM_020923.1 17 aaC/aaT 0 +ZDHHC11 UCSF GRCh37 5 837480 837480 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 245 85 294 0 ENST00000283441.8:c.900G>A p.Gln300= p.Q300= ENST00000283441 NM_024786.2 300 caG/caA 0 +ZDHHC18 UCSF GRCh37 1 27177632 27177632 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 47 122 0 ENST00000374142.4:c.846G>A p.Leu282= p.L282= ENST00000374142 NM_032283.2 282 ttG/ttA 0 +ZEB1 UCSF GRCh37 10 31810044 31810044 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 73 138 0 ENST00000361642.5:c.1784C>T p.Ser595Phe p.S595F ENST00000361642 NM_001174093.1 595 tCt/tTt 0 +ZEB1 UCSF GRCh37 10 31809528 31809528 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 168 69 127 0 ENST00000361642.5:c.1268G>A p.Gly423Asp p.G423D ENST00000361642 NM_001174093.1 423 gGt/gAt 0 +ZFAT UCSF GRCh37 8 135602547 135602547 + stop_gained Nonsense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 338 87 166 0 ENST00000377838.3:c.2527C>T p.Arg843Ter p.R843* ENST00000377838 NM_020863.3 843 Cga/Tga 0 +ZFHX3 UCSF GRCh37 16 72821844 72821844 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 60 65 114 0 ENST00000268489.5:c.10331C>T p.Ala3444Val p.A3444V ENST00000268489 NM_006885.3 3444 gCa/gTa 0 +ZFHX3 UCSF GRCh37 16 72822098 72822098 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 28 33 57 0 ENST00000268489.5:c.10077C>T p.Ser3359= p.S3359= ENST00000268489 NM_006885.3 3359 tcC/tcT 0 +ZFP106 UCSF GRCh37 15 42742112 42742112 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 110 114 191 0 ENST00000263805.4:c.2289C>T p.His763= p.H763= ENST00000263805 NM_022473.1 763 caC/caT 0 +ZFP112 UCSF GRCh37 19 44833062 44833062 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 96 103 180 0 ENST00000337401.4:c.1266G>A p.Lys422= p.K422= ENST00000337401 NM_001083335.1 422 aaG/aaA 0 +ZFP37 UCSF GRCh37 9 115805440 115805440 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 138 68 163 0 ENST00000374227.3:c.1458G>A p.Glu486= p.E486= ENST00000374227 486 gaG/gaA 0 +ZFP64 UCSF GRCh37 20 50701786 50701786 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 37 23 59 0 ENST00000361387.2:c.1248C>T p.Cys416= p.C416= ENST00000361387 NM_199427.2 416 tgC/tgT 0 +ZFR2 UCSF GRCh37 19 3819067 3819067 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 9 10 32 0 ENST00000262961.4:c.1907G>A p.Arg636Gln p.R636Q ENST00000262961 NM_015174.1 636 cGa/cAa 0 +ZFR2 UCSF GRCh37 19 3819223 3819223 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 11 6 26 0 ENST00000262961.4:c.1751G>A p.Arg584Gln p.R584Q ENST00000262961 NM_015174.1 584 cGg/cAg 0 +ZFYVE1 UCSF GRCh37 14 73437702 73437702 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 53 56 103 1 ENST00000556143.1:c.2222G>A p.Gly741Glu p.G741E ENST00000556143 NM_021260.2 741 gGa/gAa 0 +ZFYVE1 UCSF GRCh37 14 73490913 73490913 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 96 208 0 ENST00000556143.1:c.304G>A p.Glu102Lys p.E102K ENST00000556143 NM_021260.2 102 Gag/Aag 0 +ZMYM1 UCSF GRCh37 1 35559671 35559671 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 62 39 138 0 ENST00000373330.1:c.83C>T p.Pro28Leu p.P28L ENST00000373330 28 cCc/cTc 0 +ZMYND11 UCSF GRCh37 10 255829 255829 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 191 69 167 0 ENST00000397962.3:c.117G>A p.Lys39= p.K39= ENST00000397962 39 aaG/aaA 0 +ZNF131 UCSF GRCh37 5 43139398 43139398 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 95 86 177 0 ENST00000509634.1:c.358G>A p.Ala120Thr p.A120T ENST00000509634 120 Gcc/Acc 0 +ZNF142 UCSF GRCh37 2 219513823 219513823 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 47 48 88 0 ENST00000411696.2:c.808G>A p.Glu270Lys p.E270K ENST00000411696 270 Gag/Aag 0 +ZNF16 UCSF GRCh37 8 146157636 146157636 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 389 101 194 0 ENST00000276816.4:c.537G>A p.Arg179= p.R179= ENST00000276816 NM_001029976.2 179 agG/agA 0 +ZNF165 UCSF GRCh37 6 28056718 28056718 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 55 43 119 0 ENST00000377325.1:c.928C>T p.His310Tyr p.H310Y ENST00000377325 NM_003447.3 310 Cat/Tat 0 +ZNF184 UCSF GRCh37 6 27420104 27420104 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 65 62 173 0 ENST00000211936.6:c.1234C>T p.His412Tyr p.H412Y ENST00000211936 NM_007149.2 412 Cat/Tat 0 +ZNF187 UCSF GRCh37 6 28244609 28244609 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 93 225 0 ENST00000421553.2:n.1443C>T *481* ENST00000421553 0 +ZNF224 UCSF GRCh37 19 44611321 44611321 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0011 P10_Rec Untested WXS Illumina HiSeq 164 136 255 0 ENST00000336976.6:c.1008G>A p.Met336Ile p.M336I ENST00000336976 NM_013398.2 336 atG/atA 0 +ZNF259 UCSF GRCh37 11 116650508 116650508 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 49 146 0 ENST00000227322.3:c.1225G>A p.Ala409Thr p.A409T ENST00000227322 NM_003904.3 409 Gca/Aca 0 +ZNF280C UCSF GRCh37 X 129339294 129339294 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 73 155 1 ENST00000370978.4:c.2138C>T p.Thr713Ile p.T713I ENST00000370978 NM_017666.4 713 aCt/aTt 0 +ZNF281 UCSF GRCh37 1 200377972 200377972 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 131 134 191 0 ENST00000294740.3:c.862C>T p.Pro288Ser p.P288S ENST00000294740 NM_001281293.1 288 Cct/Tct 0 +ZNF282 UCSF GRCh37 7 148907734 148907734 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 12 13 28 0 ENST00000262085.3:c.890C>T p.Thr297Ile p.T297I ENST00000262085 NM_003575.2 297 aCc/aTc 0 +ZNF3 UCSF GRCh37 7 99669573 99669573 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 124 103 206 0 ENST00000303915.6:c.534G>A p.Gly178= p.G178= ENST00000303915 178 ggG/ggA 0 +ZNF300 UCSF GRCh37 5 150275333 150275333 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 84 58 154 0 ENST00000446148.2:c.1516G>A p.Glu506Lys p.E506K ENST00000446148 NM_001172831.1 506 Gaa/Aaa 0 +ZNF317 UCSF GRCh37 19 9269574 9269574 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 45 37 96 0 ENST00000247956.6:c.458G>A p.Gly153Asp p.G153D ENST00000247956 NM_020933.4 153 gGt/gAt 0 +ZNF324B UCSF GRCh37 19 58966831 58966831 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 49 91 0 ENST00000336614.4:c.520C>T p.Pro174Ser p.P174S ENST00000336614 NM_207395.2 174 Ccc/Tcc 0 +ZNF385A UCSF GRCh37 12 54764711 54764711 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 59 64 117 0 ENST00000338010.5:c.834G>A p.Gln278= p.Q278= ENST00000338010 NM_001130967.1 278 caG/caA 0 +ZNF410 UCSF GRCh37 14 74388848 74388848 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 63 64 116 0 ENST00000442160.3:c.1260C>T p.Pro420= p.P420= ENST00000442160 NM_001242924.1 420 ccC/ccT 0 +ZNF415 UCSF GRCh37 19 53619578 53619578 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 148 116 251 0 ENST00000500065.4:c.124C>T p.Leu42= p.L42= ENST00000500065 NM_001136038.2 42 Ctg/Ttg 0 +ZNF423 UCSF GRCh37 16 49669888 49669888 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 24 24 56 0 ENST00000561648.1:c.3175G>A p.Gly1059Arg p.G1059R ENST00000561648 NM_015069.3 1059 Ggg/Agg 0 +ZNF425 UCSF GRCh37 7 148815372 148815372 + stop_gained Nonsense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 121 177 0 ENST00000378061.2:c.87G>A p.Trp29Ter p.W29* ENST00000378061 NM_001001661.2 29 tgG/tgA 0 +ZNF429 UCSF GRCh37 19 21719844 21719844 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 94 106 213 0 ENST00000358491.4:c.989G>A p.Ser330Asn p.S330N ENST00000358491 NM_001001415.2 330 aGc/aAc 0 +ZNF43 UCSF GRCh37 19 21990809 21990809 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 129 104 208 0 ENST00000354959.4:c.2030C>T p.Pro677Leu p.P677L ENST00000354959 NM_003423.3 677 cCc/cTc 0 +ZNF432 UCSF GRCh37 19 52537701 52537701 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 112 99 235 0 ENST00000594154.1:c.1231C>T p.Pro411Ser p.P411S ENST00000594154 411 Ccc/Tcc 0 +ZNF445 UCSF GRCh37 3 44489299 44489299 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 4 106 185 0 ENST00000425708.2:c.1864G>A p.Glu622Lys p.E622K ENST00000425708 622 Gag/Aag 0 +ZNF449 UCSF GRCh37 X 134481311 134481311 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 97 64 176 0 ENST00000339249.4:c.268G>A p.Val90Met p.V90M ENST00000339249 NM_152695.5 90 Gtg/Atg 0 +ZNF460 UCSF GRCh37 19 57795929 57795929 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 66 195 0 ENST00000360338.3:c.41C>T p.Thr14Ile p.T14I ENST00000360338 NM_006635.3 14 aCc/aTc 0 +ZNF470 UCSF GRCh37 19 57089633 57089633 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 81 62 130 0 ENST00000330619.8:c.1836G>A p.Gln612= p.Q612= ENST00000330619 NM_001001668.3 612 caG/caA 0 +ZNF483 UCSF GRCh37 9 114304687 114304687 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 144 57 129 0 ENST00000309235.5:c.1472G>A p.Gly491Glu p.G491E ENST00000309235 NM_133464.2 491 gGa/gAa 0 +ZNF484 UCSF GRCh37 9 95610568 95610568 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 240 111 209 0 ENST00000395506.3:c.507C>T p.His169= p.H169= ENST00000395506 169 caC/caT 0 +ZNF516 UCSF GRCh37 18 74091782 74091782 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 41 39 65 1 ENST00000443185.2:c.2288C>T p.Pro763Leu p.P763L ENST00000443185 NM_014643.3 763 cCt/cTt 0 +ZNF527 UCSF GRCh37 19 37880574 37880574 + synonymous_variant Silent SNP T T C NOVEL P10_Rec Untested WXS Illumina HiSeq 71 79 132 0 ENST00000436120.2:c.1623T>C p.Leu541= p.L541= ENST00000436120 NM_032453.1 541 ctT/ctC 0 +ZNF541 UCSF GRCh37 19 48058965 48058965 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec somatic WXS Sanger Illumina HiSeq 38 49 79 0 ENST00000314121.4:c.149G>A p.Ser50Asn p.S50N ENST00000314121 50 aGt/aAt 0 +ZNF543 UCSF GRCh37 19 57839758 57839758 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 109 77 205 0 ENST00000321545.4:c.928C>T p.Pro310Ser p.P310S ENST00000321545 NM_213598.3 310 Ccc/Tcc 0 +ZNF543 UCSF GRCh37 19 57840242 57840242 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 108 95 154 0 ENST00000321545.4:c.1412G>A p.Ser471Asn p.S471N ENST00000321545 NM_213598.3 471 aGc/aAc 0 +ZNF547 UCSF GRCh37 19 57888578 57888578 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 79 61 154 0 ENST00000282282.3:c.234G>A p.Lys78= p.K78= ENST00000282282 NM_173631.2 78 aaG/aaA 0 +ZNF554 UCSF GRCh37 19 2834661 2834661 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 80 86 145 0 ENST00000317243.5:c.1428G>A p.Arg476= p.R476= ENST00000317243 NM_001102651.1 476 agG/agA 0 +ZNF578 UCSF GRCh37 19 53014224 53014224 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 144 102 234 0 ENST00000421239.2:c.590C>T p.Ser197Phe p.S197F ENST00000421239 NM_001099694.1 197 tCt/tTt 0 +ZNF582 UCSF GRCh37 19 56895688 56895688 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 89 82 204 0 ENST00000301310.4:c.1098C>T p.Pro366= p.P366= ENST00000301310 NM_144690.1 366 ccC/ccT 0 +ZNF585A UCSF GRCh37 19 37643323 37643323 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 84 81 181 0 ENST00000292841.5:c.1313C>T p.Ser438Phe p.S438F ENST00000292841 NM_152655.2 438 tCt/tTt 0 +ZNF585B UCSF GRCh37 19 37677780 37677780 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 106 93 180 0 ENST00000532828.2:c.659G>A p.Gly220Glu p.G220E ENST00000532828 NM_152279.3 220 gGg/gAg 0 +ZNF592 UCSF GRCh37 15 85326624 85326624 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 113 84 177 0 ENST00000299927.3:c.718G>A p.Glu240Lys p.E240K ENST00000299927 240 Gaa/Aaa 0 +ZNF598 UCSF GRCh37 16 2049509 2049509 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 13 15 19 0 ENST00000431526.1:c.2041C>T p.Pro681Ser p.P681S ENST00000431526 681 Ccg/Tcg 0 +ZNF607 UCSF GRCh37 19 38189934 38189934 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 130 87 192 0 ENST00000355202.4:c.1098G>A p.Lys366= p.K366= ENST00000355202 NM_032689.4 366 aaG/aaA 0 +ZNF609 UCSF GRCh37 15 64973532 64973532 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 130 96 205 0 ENST00000326648.3:c.4187C>T p.Ala1396Val p.A1396V ENST00000326648 NM_015042.1 1396 gCc/gTc 0 +ZNF609 UCSF GRCh37 15 64967741 64967741 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 91 67 186 0 ENST00000326648.3:c.2688G>A p.Glu896= p.E896= ENST00000326648 NM_015042.1 896 gaG/gaA 0 +ZNF622 UCSF GRCh37 5 16465647 16465647 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 57 43 97 0 ENST00000308683.2:c.128C>T p.Thr43Ile p.T43I ENST00000308683 NM_033414.2 43 aCc/aTc 0 +ZNF623 UCSF GRCh37 8 144733633 144733633 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 264 60 116 0 ENST00000501748.2:c.1591G>A p.Glu531Lys p.E531K ENST00000501748 NM_014789.3 531 Gaa/Aaa 0 +ZNF623 UCSF GRCh37 8 144732450 144732450 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.309,1000g2011may_all_0.3611,snp132_rs3750204 P10_Rec Untested WXS Illumina HiSeq 352 85 183 0 ENST00000501748.2:c.408G>A p.Ser136= p.S136= ENST00000501748 NM_014789.3 136 tcG/tcA 0 +ZNF627 UCSF GRCh37 19 11727672 11727672 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 141 103 223 0 ENST00000361113.5:c.354G>A p.Arg118= p.R118= ENST00000361113 NM_145295.3 118 agG/agA 0 +ZNF639 UCSF GRCh37 3 179051833 179051833 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 118 116 206 0 ENST00000326361.3:c.1081C>T p.Leu361Phe p.L361F ENST00000326361 NM_016331.1 361 Ctc/Ttc 0 +ZNF645 UCSF GRCh37 X 22291520 22291520 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 99 89 183 0 ENST00000323684.1:c.412C>T p.His138Tyr p.H138Y ENST00000323684 NM_152577.3 138 Cat/Tat 0 +ZNF658 UCSF GRCh37 9 40773158 40773158 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 223 127 241 0 ENST00000602553.1:c.2117G>A p.Arg706Lys p.R706K ENST00000602553 706 aGa/aAa 0 +ZNF665 UCSF GRCh37 19 53668410 53668410 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 119 124 233 0 ENST00000396424.3:c.1333C>T p.Leu445= p.L445= ENST00000396424 NM_024733.3 445 Cta/Tta 0 +ZNF668 UCSF GRCh37 16 31075243 31075243 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 10 9 23 0 ENST00000539836.3:c.607C>T p.Pro203Ser p.P203S ENST00000539836 NM_001172669.1 203 Cct/Tct 0 +ZNF668 UCSF GRCh37 16 31075703 31075703 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 34 33 94 0 ENST00000539836.3:c.147C>T p.Ser49= p.S49= ENST00000539836 NM_001172669.1 49 tcC/tcT 0 +ZNF700 UCSF GRCh37 19 12060846 12060846 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 111 119 197 0 ENST00000254321.5:c.2007G>A p.Lys669= p.K669= ENST00000254321 NM_144566.2 669 aaG/aaA 0 +ZNF711 UCSF GRCh37 X 84526171 84526171 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 48 51 133 0 ENST00000373165.3:c.1623G>A p.Arg541= p.R541= ENST00000373165 NM_021998.4 541 agG/agA 0 +ZNF749 UCSF GRCh37 19 57953330 57953330 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 129 120 207 0 ENST00000334181.4:c.93C>T p.His31= p.H31= ENST00000334181 NM_001023561.2 31 caC/caT 0 +ZNF750 UCSF GRCh37 17 80789491 80789491 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 54 62 124 0 ENST00000269394.3:c.840C>T p.Asp280= p.D280= ENST00000269394 NM_024702.2 280 gaC/gaT 0 +ZNF76 UCSF GRCh37 6 35255438 35255438 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 46 51 113 0 ENST00000373953.3:c.248G>A p.Ser83Asn p.S83N ENST00000373953 NM_003427.3 83 aGc/aAc 0 +ZNF761 UCSF GRCh37 19 53958841 53958841 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 149 128 221 0 ENST00000454407.1:n.1533C>T *511* ENST00000454407 0 +ZNF764 UCSF GRCh37 16 30569472 30569472 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 6 15 23 0 ENST00000252797.2:c.32G>A p.Arg11Gln p.R11Q ENST00000252797 NM_033410.3 11 cGg/cAg 0 +ZNF766 UCSF GRCh37 19 52793879 52793879 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 93 93 195 0 ENST00000439461.1:c.835G>A p.Val279Ile p.V279I ENST00000439461 NM_001010851.2 279 Gtc/Atc 0 +ZNF770 UCSF GRCh37 15 35273889 35273889 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 112 101 221 0 ENST00000356321.4:c.1747G>A p.Glu583Lys p.E583K ENST00000356321 NM_014106.3 583 Gag/Aag 0 +ZNF770 UCSF GRCh37 15 35274604 35274604 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 43 28 94 0 ENST00000356321.4:c.1032G>A p.Lys344= p.K344= ENST00000356321 NM_014106.3 344 aaG/aaA 0 +ZNF777 UCSF GRCh37 7 149129924 149129924 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 22 21 26 0 ENST00000247930.4:c.1439G>A p.Gly480Glu p.G480E ENST00000247930 NM_015694.2 480 gGg/gAg 0 +ZNF777 UCSF GRCh37 7 149153033 149153033 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 51 61 128 0 ENST00000247930.4:c.81C>T p.Leu27= p.L27= ENST00000247930 NM_015694.2 27 ctC/ctT 0 +ZNF804A UCSF GRCh37 2 185803266 185803266 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 108 103 190 0 ENST00000302277.6:c.3143C>T p.Pro1048Leu p.P1048L ENST00000302277 NM_194250.1 1048 cCa/cTa 0 +ZNF804A UCSF GRCh37 2 185802611 185802611 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 88 204 0 ENST00000302277.6:c.2488G>A p.Glu830Lys p.E830K ENST00000302277 NM_194250.1 830 Gaa/Aaa 0 +ZNF808 UCSF GRCh37 19 53057091 53057091 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 158 133 271 0 ENST00000359798.4:c.922C>T p.Leu308Phe p.L308F ENST00000359798 NM_001039886.3 308 Ctt/Ttt 0 +ZNF812 UCSF GRCh37 19 9801409 9801409 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 61 194 0 ENST00000457674.2:c.770C>T p.Ser257Phe p.S257F ENST00000457674 NM_001199814.1 257 tCc/tTc 0 +ZNF814 UCSF GRCh37 19 58384320 58384320 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 125 109 223 0 ENST00000435989.2:c.2438C>T p.Ser813Phe p.S813F ENST00000435989 NM_001144989.1 813 tCc/tTc 0 +ZNF814 UCSF GRCh37 19 58386317 58386317 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 104 83 254 0 ENST00000435989.2:c.441C>T p.Pro147= p.P147= ENST00000435989 NM_001144989.1 147 ccC/ccT 0 +ZNF828 UCSF GRCh37 13 115090865 115090865 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 144 143 224 0 ENST00000361283.1:c.1548G>A p.Lys516= p.K516= ENST00000361283 NM_032436.2 516 aaG/aaA 0 +ZNF839 UCSF GRCh37 14 102807822 102807822 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 65 51 135 0 ENST00000442396.2:c.2090C>T p.Ser697Phe p.S697F ENST00000442396 697 tCc/tTc 0 +ZNF878 UCSF GRCh37 19 12155717 12155717 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 154 125 231 0 ENST00000547628.1:c.499G>A p.Ala167Thr p.A167T ENST00000547628 NM_001080404.2 167 Gca/Aca 0 +ZNHIT6 UCSF GRCh37 1 86173894 86173894 + missense_variant Missense_Mutation SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 66 64 146 0 ENST00000370574.3:c.74G>A p.Ser25Asn p.S25N ENST00000370574 25 aGt/aAt 0 +ZNRF3 UCSF GRCh37 22 29438558 29438558 + splice_donor_variant Splice_Site SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 44 37 68 0 ENST00000544604.2:c.501+1G>A p.X167_splice ENST00000544604 NM_001206998.1 0 +ZNRF3 UCSF GRCh37 22 29445444 29445444 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 37 47 67 0 ENST00000544604.2:c.1275C>T p.Asp425= p.D425= ENST00000544604 NM_001206998.1 425 gaC/gaT 0 +ZP2 UCSF GRCh37 16 21212793 21212793 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 90 79 158 0 ENST00000574002.1:c.1591C>T p.Leu531= p.L531= ENST00000574002 531 Cta/Tta 0 +ZP4 UCSF GRCh37 1 238053862 238053862 + missense_variant Missense_Mutation SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 68 53 119 0 ENST00000366570.4:c.74C>T p.Ala25Val p.A25V ENST00000366570 NM_021186.3 25 gCa/gTa 0 +ZSCAN20 UCSF GRCh37 1 33961067 33961067 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 52 43 90 0 ENST00000361328.3:c.3123G>A p.Lys1041= p.K1041= ENST00000361328 NM_145238.3 1041 aaG/aaA 0 +ZSCAN29 UCSF GRCh37 15 43654045 43654045 + synonymous_variant Silent SNP C C T NOVEL P10_Rec Untested WXS Illumina HiSeq 87 76 184 0 ENST00000396976.2:c.1785G>A p.Arg595= p.R595= ENST00000396976 NM_152455.3 595 agG/agA 0 +ZSWIM6 UCSF GRCh37 5 60839601 60839601 + synonymous_variant Silent SNP G G A NOVEL P10_Rec Untested WXS Illumina HiSeq 75 69 130 0 ENST00000252744.5:c.3105G>A p.Arg1035= p.R1035= ENST00000252744 NM_020928.1 1035 cgG/cgA 0 +ARID2 UCSF GRCh37 12 46242691 46242691 + synonymous_variant Silent SNP G G C NOVEL P11_Pri Untested WXS Illumina HiSeq 90 67 110 0 ENST00000334344.6:c.1653G>C p.Ser551= p.S551= ENST00000334344 NM_152641.2 551 tcG/tcC 0 +ATRX UCSF GRCh37 X 76938945 76938951 + frameshift_variant Frame_Shift_Del DEL TTTAATT TTTAATT - NOVEL P11_Pri Untested WXS Illumina HiSeq 88 0 ENST00000373344.5:c.1797_1803del p.Ile600ValfsTer19 p.I600Vfs*19 ENST00000373344 NM_000489.3 599 ccAATTAAA/cc 0 +CFTR UCSF GRCh37 7 117171029 117171029 + missense_variant Missense_Mutation SNP G G A snp132_rs78655421 P11_Pri Untested WXS Illumina HiSeq 49 39 82 0 ENST00000003084.6:c.350G>A p.Arg117His p.R117H ENST00000003084 NM_000492.3 117 cGc/cAc 0 +DDR1 UCSF GRCh37 6 30865364 30865364 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 33 17 42 0 ENST00000376575.3:c.2224C>T p.Pro742Ser p.P742S ENST00000376575 742 Ccc/Tcc 0 +DUX2 UCSF GRCh37 4 190989798 190989798 + non_coding_transcript_exon_variant RNA SNP G G C NOVEL P11_Pri Untested WXS Illumina HiSeq 14 4 26 1 ENST00000536428.1:n.1003G>C *335* ENST00000536428 0 +FLT4 UCSF GRCh37 5 180038348 180038348 + synonymous_variant Silent SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 55 25 60 0 ENST00000261937.6:c.3669C>T p.Arg1223= p.R1223= ENST00000261937 NM_182925.4 1223 cgC/cgT 0 +GOLGA1 UCSF GRCh37 9 127651492 127651492 + missense_variant Missense_Mutation SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 34 6 44 0 ENST00000373555.4:c.1691C>T p.Ala564Val p.A564V ENST00000373555 NM_002077.3 564 gCg/gTg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 97 70 123 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIAA1958 UCSF GRCh37 9 115336728 115336728 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 81 70 148 0 ENST00000337530.6:c.368C>T p.Ser123Phe p.S123F ENST00000337530 NM_001287038.1 123 tCc/tTc 0 +KIAA2026 UCSF GRCh37 9 5920588 5920588 + missense_variant Missense_Mutation SNP G G T NOVEL P11_Pri Untested WXS Illumina HiSeq 193 40 352 0 ENST00000399933.3:c.5408C>A p.Thr1803Lys p.T1803K ENST00000399933 NM_001017969.2 1803 aCa/aAa 0 +MADCAM1 UCSF GRCh37 19 501701 501701 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.144,1000g2011may_all_0.1863,snp132_rs72970252 P11_Pri Untested WXS Illumina HiSeq 50 7 44 1 ENST00000215637.3:c.700G>A p.Asp234Asn p.D234N ENST00000215637 NM_130760.2 234 Gac/Aac 0 +MKI67 UCSF GRCh37 10 129904284 129904284 + synonymous_variant Silent SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 115 44 236 0 ENST00000368654.3:c.5820G>A p.Arg1940= p.R1940= ENST00000368654 NM_002417.4 1940 cgG/cgA 0 +MYO10 UCSF GRCh37 5 16711041 16711041 + synonymous_variant Silent SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 98 24 118 0 ENST00000513610.1:c.2145C>T p.Ser715= p.S715= ENST00000513610 NM_012334.2 715 agC/agT 0 +NYNRIN UCSF GRCh37 14 24878453 24878453 + missense_variant Missense_Mutation SNP T T C NOVEL P11_Pri Untested WXS Illumina HiSeq 61 27 87 0 ENST00000382554.3:c.1453T>C p.Ser485Pro p.S485P ENST00000382554 NM_025081.2 485 Tct/Cct 0 +PHKA2 UCSF GRCh37 X 18924630 18924630 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Pri Untested WXS Illumina HiSeq 25 26 78 0 ENST00000379942.4:c.2789G>A p.Arg930Gln p.R930Q ENST00000379942 NM_000292.2 930 cGg/cAg 0 +PKD1L1 UCSF GRCh37 7 47913571 47913571 + synonymous_variant Silent SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 31 29 45 0 ENST00000289672.2:c.3822C>T p.Ser1274= p.S1274= ENST00000289672 NM_138295.3 1274 tcC/tcT 0 +PLCH1 UCSF GRCh37 3 155200415 155200415 + missense_variant Missense_Mutation SNP T T C NOVEL P11_Pri Untested WXS Illumina HiSeq 104 15 107 0 ENST00000340059.7:c.3424A>G p.Arg1142Gly p.R1142G ENST00000340059 NM_001130960.1 1142 Agg/Ggg 0 +PTCRA UCSF GRCh37 6 42893351 42893351 + synonymous_variant Silent SNP T T G NOVEL P11_Pri Untested WXS Illumina HiSeq 12 15 27 0 ENST00000304672.1:c.777T>G p.Ala259= p.A259= ENST00000304672 NM_001243168.1 259 gcT/gcG 0 +RGS5 UCSF GRCh37 1 163138051 163138051 + missense_variant Missense_Mutation SNP T T A NOVEL P11_Pri Untested WXS Illumina HiSeq 105 34 171 0 ENST00000530507.1:c.152A>T p.Gln51Leu p.Q51L ENST00000530507 51 cAg/cTg 0 +SIDT2 UCSF GRCh37 11 117060735 117060735 + missense_variant Missense_Mutation SNP A A G NOVEL P11_Pri Untested WXS Illumina HiSeq 54 35 122 0 ENST00000324225.4:c.1487A>G p.Asn496Ser p.N496S ENST00000324225 NM_001040455.1 496 aAt/aGt 0 +SLAMF1 UCSF GRCh37 1 160589601 160589601 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P11_Pri Untested WXS Illumina HiSeq 6 0 ENST00000302035.6:c.829delA p.Ser277AlafsTer54 p.S277Afs*54 ENST00000302035 NM_003037.2 277 Agc/gc 0 +SLX4 UCSF GRCh37 16 3633500 3633500 + missense_variant Missense_Mutation SNP C C A NOVEL P11_Pri Untested WXS Illumina HiSeq 77 10 85 0 ENST00000294008.3:c.4751G>T p.Arg1584Leu p.R1584L ENST00000294008 NM_032444.2 1584 cGc/cTc 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P11_Pri Untested WXS Illumina HiSeq 11 71 50 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TXNDC3 UCSF GRCh37 7 37936603 37936603 + missense_variant Missense_Mutation SNP G G T NOVEL P11_Pri Untested WXS Illumina HiSeq 88 23 143 0 ENST00000199447.4:c.1676G>T p.Ser559Ile p.S559I ENST00000199447 NM_016616.4 559 aGt/aTt 0 +UNC5C UCSF GRCh37 4 96104084 96104084 + synonymous_variant Silent SNP T T C NOVEL P11_Pri Untested WXS Illumina HiSeq 91 62 153 0 ENST00000453304.1:c.2415A>G p.Glu805= p.E805= ENST00000453304 NM_003728.3 805 gaA/gaG 0 +WASH1 UCSF GRCh37 9 16967 16967 + splice_region_variant,non_coding_transcript_exon_variant Splice_Region SNP A A G 1000g2011may_all_0.2384,snp132_rs17857353 P11_Pri Untested WXS Illumina HiSeq 42 7 40 0 ENST00000442898.2:n.1024T>C p.X342_splice ENST00000442898 0 +ZNF483 UCSF GRCh37 9 114304413 114304413 + missense_variant Missense_Mutation SNP A A C NOVEL P11_Pri Untested WXS Illumina HiSeq 120 102 195 0 ENST00000309235.5:c.1198A>C p.Ile400Leu p.I400L ENST00000309235 NM_133464.2 400 Att/Ctt 0 +ALDH3B1 UCSF GRCh37 11 67795299 67795299 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.237,1000g2011may_all_0.3285,snp132_rs308341 P11_Rec Untested WXS Illumina HiSeq 5 11 8 0 ENST00000539229.1:c.1293G>A p.Pro431= p.P431= ENST00000539229 NM_001161473.1 431 ccG/ccA 0 +APOF UCSF GRCh37 12 56755364 56755364 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P11_Rec Untested WXS Illumina HiSeq 10 0 ENST00000398189.3:c.626del p.Lys209ArgfsTer11 p.K209Rfs*11 ENST00000398189 NM_001638.2 209 aAg/ag 0 +ARID2 UCSF GRCh37 12 46242691 46242691 + synonymous_variant Silent SNP G G C NOVEL P11_Rec Untested WXS Illumina HiSeq 75 42 110 0 ENST00000334344.6:c.1653G>C p.Ser551= p.S551= ENST00000334344 NM_152641.2 551 tcG/tcC 0 +ATRX UCSF GRCh37 X 76938945 76938951 + frameshift_variant Frame_Shift_Del DEL TTTAATT TTTAATT - NOVEL P11_Rec Untested WXS Illumina HiSeq 65 0 ENST00000373344.5:c.1797_1803del p.Ile600ValfsTer19 p.I600Vfs*19 ENST00000373344 NM_000489.3 599 ccAATTAAA/cc 0 +C7orf57 UCSF GRCh37 7 48080945 48080945 + missense_variant Missense_Mutation SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 102 15 115 1 ENST00000348904.3:c.70G>A p.Val24Ile p.V24I ENST00000348904 NM_001100159.2 24 Gtc/Atc 0 +CFTR UCSF GRCh37 7 117171029 117171029 + missense_variant Missense_Mutation SNP G G A snp132_rs78655421 P11_Rec Untested WXS Illumina HiSeq 62 26 82 0 ENST00000003084.6:c.350G>A p.Arg117His p.R117H ENST00000003084 NM_000492.3 117 cGc/cAc 0 +CLIP1 UCSF GRCh37 12 122758571 122758599 + splice_donor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TTCATATGAAATACCTGTCATAATTGTTT TTCATATGAAATACCTGTCATAATTGTTT - NOVEL P11_Rec Untested WXS Illumina HiSeq 6 0 ENST00000540338.1:c.4077_4091+14del p.X1359_splice ENST00000540338 1359 0 +CREG2 UCSF GRCh37 2 101971731 101971731 + missense_variant Missense_Mutation SNP G G T NOVEL P11_Rec Untested WXS Illumina HiSeq 72 12 52 1 ENST00000324768.5:c.709C>A p.Gln237Lys p.Q237K ENST00000324768 NM_153836.3 237 Caa/Aaa 0 +CROCC UCSF GRCh37 1 17272075 17272075 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.064,1000g2011may_all_0.0426,snp132_rs2781608 P11_Rec Untested WXS Illumina HiSeq 15 4 26 1 ENST00000375541.5:c.2110G>A p.Ala704Thr p.A704T ENST00000375541 NM_014675.3 704 Gcc/Acc 0 +CYP21A2 UCSF GRCh37 6 31975463 31975463 + non_coding_transcript_exon_variant RNA SNP T T C 1000g2011may_all_0.0497,snp132_rs7755898 P11_Rec Untested WXS Illumina HiSeq 18 4 12 0 ENST00000342991.6:n.1386T>C *462* ENST00000342991 0 +DDR1 UCSF GRCh37 6 30865364 30865364 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 39 28 42 0 ENST00000376575.3:c.2224C>T p.Pro742Ser p.P742S ENST00000376575 742 Ccc/Tcc 0 +DEFB126 UCSF GRCh37 20 126310 126311 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P11_Rec Untested WXS Illumina HiSeq 6 0 ENST00000382398.3:c.313_314del p.Thr105ProfsTer? p.T105Pfs*? ENST00000382398 NM_030931.3 105 ACc/c 0 +FLT4 UCSF GRCh37 5 180038348 180038348 + synonymous_variant Silent SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 51 22 60 0 ENST00000261937.6:c.3669C>T p.Arg1223= p.R1223= ENST00000261937 NM_182925.4 1223 cgC/cgT 0 +GGTLC1 UCSF GRCh37 20 23967157 23967157 + missense_variant Missense_Mutation SNP A A G NOVEL P11_Rec Untested WXS Illumina HiSeq 37 12 53 0 ENST00000335694.4:c.92T>C p.Met31Thr p.M31T ENST00000335694 NM_178311.2 31 aTg/aCg 0 +GNRH2 UCSF GRCh37 20 3026346 3026347 + frameshift_variant Frame_Shift_Ins INS - - GCCCC NOVEL P11_Rec Untested WXS Illumina HiSeq 6 0 ENST00000245983.2:c.327_328insGCCCC p.Pro110AlafsTer? p.P110Afs*? ENST00000245983 NM_001501.1 109 -/GCCCC 0 +GPRC5B UCSF GRCh37 16 19883854 19883854 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 50 8 46 0 ENST00000300571.2:c.314G>A p.Gly105Asp p.G105D ENST00000300571 NM_016235.1 105 gGc/gAc 0 +HLA-A UCSF GRCh37 6 29910572 29910572 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.067,1000g2011may_all_0.0966,snp132_rs114101108 P11_Rec Untested WXS Illumina HiSeq 26 5 38 0 ENST00000376809.5:c.112C>T p.Arg38Trp p.R38W ENST00000376809 NM_002116.7 38 Cgg/Tgg 0 +HLA-A UCSF GRCh37 6 29910558 29910558 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.473,1000g2011may_all_0.5687,snp132_rs112039894 P11_Rec Untested WXS Illumina HiSeq 19 4 37 1 ENST00000376809.5:c.98T>C p.Phe33Ser p.F33S ENST00000376809 NM_002116.7 33 tTc/tCc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 100 60 123 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KBTBD6 UCSF GRCh37 13 41704817 41704820 + frameshift_variant Frame_Shift_Del DEL AGTT AGTT - NOVEL P11_Rec Untested WXS Illumina HiSeq 7 0 ENST00000379485.1:c.1828_1831del p.Asn610PhefsTer36 p.N610Ffs*36 ENST00000379485 NM_152903.4 610 AACTtt/tt 0 +KIAA1958 UCSF GRCh37 9 115336728 115336728 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 92 60 148 0 ENST00000337530.6:c.368C>T p.Ser123Phe p.S123F ENST00000337530 NM_001287038.1 123 tCc/tTc 0 +KIAA2026 UCSF GRCh37 9 5920588 5920588 + missense_variant Missense_Mutation SNP G G T NOVEL P11_Rec Untested WXS Illumina HiSeq 231 37 352 0 ENST00000399933.3:c.5408C>A p.Thr1803Lys p.T1803K ENST00000399933 NM_001017969.2 1803 aCa/aAa 0 +MIS18BP1 UCSF GRCh37 14 45716019 45716020 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P11_Rec Untested WXS Illumina HiSeq 6 0 ENST00000310806.4:c.471dup p.Leu158IlefsTer8 p.L158Ifs*8 ENST00000310806 NM_018353.4 157 aaa/aaAa 0 +MKI67 UCSF GRCh37 10 129904284 129904284 + synonymous_variant Silent SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 157 34 236 0 ENST00000368654.3:c.5820G>A p.Arg1940= p.R1940= ENST00000368654 NM_002417.4 1940 cgG/cgA 0 +MST1 UCSF GRCh37 3 49723545 49723545 + missense_variant Missense_Mutation SNP G G A snp132_rs4052562 P11_Rec Untested WXS Illumina HiSeq 32 6 25 1 ENST00000449682.2:c.1097C>T p.Ala366Val p.A366V ENST00000449682 NM_020998.3 366 gCg/gTg 0 +MST1 UCSF GRCh37 3 49723542 49723542 + missense_variant Missense_Mutation SNP G G C snp132_rs2087732 P11_Rec Untested WXS Illumina HiSeq 33 6 25 1 ENST00000449682.2:c.1100C>G p.Ala367Gly p.A367G ENST00000449682 NM_020998.3 367 gCc/gGc 0 +MYO10 UCSF GRCh37 5 16711041 16711041 + synonymous_variant Silent SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 125 24 118 0 ENST00000513610.1:c.2145C>T p.Ser715= p.S715= ENST00000513610 NM_012334.2 715 agC/agT 0 +NBPF4 UCSF GRCh37 1 108769307 108769307 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.062,1000g2011may_all_0.2082,snp132_rs2582071 P11_Rec Untested WXS Illumina HiSeq 72 10 79 1 ENST00000415641.3:c.1869C>T p.Ser623= p.S623= ENST00000415641 NM_001143989.2 623 agC/agT 0 +NYNRIN UCSF GRCh37 14 24878453 24878453 + missense_variant Missense_Mutation SNP T T C NOVEL P11_Rec Untested WXS Illumina HiSeq 86 37 87 0 ENST00000382554.3:c.1453T>C p.Ser485Pro p.S485P ENST00000382554 NM_025081.2 485 Tct/Cct 0 +PEAK1 UCSF GRCh37 15 77473938 77473939 + frameshift_variant Frame_Shift_Del DEL AG AG - NOVEL P11_Rec Untested WXS Illumina HiSeq 7 0 ENST00000560626.2:c.330_331del p.Leu111GlufsTer6 p.L111Efs*6 ENST00000560626 110 gcCTtg/gctg 0 +PHKA2 UCSF GRCh37 X 18924630 18924630 + missense_variant Missense_Mutation SNP C C T NOVEL P11_Rec Untested WXS Illumina HiSeq 56 37 78 0 ENST00000379942.4:c.2789G>A p.Arg930Gln p.R930Q ENST00000379942 NM_000292.2 930 cGg/cAg 0 +PKD1L1 UCSF GRCh37 7 47913571 47913571 + synonymous_variant Silent SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 32 25 45 0 ENST00000289672.2:c.3822C>T p.Ser1274= p.S1274= ENST00000289672 NM_138295.3 1274 tcC/tcT 0 +PTCRA UCSF GRCh37 6 42893351 42893351 + synonymous_variant Silent SNP T T G NOVEL P11_Rec Untested WXS Illumina HiSeq 17 9 27 0 ENST00000304672.1:c.777T>G p.Ala259= p.A259= ENST00000304672 NM_001243168.1 259 gcT/gcG 0 +RGS5 UCSF GRCh37 1 163138051 163138051 + missense_variant Missense_Mutation SNP T T A NOVEL P11_Rec Untested WXS Illumina HiSeq 129 29 171 0 ENST00000530507.1:c.152A>T p.Gln51Leu p.Q51L ENST00000530507 51 cAg/cTg 0 +SIDT2 UCSF GRCh37 11 117060735 117060735 + missense_variant Missense_Mutation SNP A A G NOVEL P11_Rec Untested WXS Illumina HiSeq 84 48 122 0 ENST00000324225.4:c.1487A>G p.Asn496Ser p.N496S ENST00000324225 NM_001040455.1 496 aAt/aGt 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P11_Rec Untested WXS Illumina HiSeq 26 58 50 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TPSAB1 UCSF GRCh37 16 1291639 1291639 + synonymous_variant Silent SNP A A G snp132_rs1064783 P11_Rec Untested WXS Illumina HiSeq 75 9 60 1 ENST00000338844.3:c.438A>G p.Ser146= p.S146= ENST00000338844 NM_003294.3 146 tcA/tcG 0 +UNC5C UCSF GRCh37 4 96104084 96104084 + synonymous_variant Silent SNP T T C NOVEL P11_Rec Untested WXS Illumina HiSeq 107 35 153 0 ENST00000453304.1:c.2415A>G p.Glu805= p.E805= ENST00000453304 NM_003728.3 805 gaA/gaG 0 +WDR81 UCSF GRCh37 17 1637482 1637482 + synonymous_variant Silent SNP G G T NOVEL P11_Rec Untested WXS Illumina HiSeq 29 4 27 0 ENST00000409644.1:c.5151G>T p.Gly1717= p.G1717= ENST00000409644 NM_001163809.1 1717 ggG/ggT 0 +ZNF483 UCSF GRCh37 9 114304413 114304413 + missense_variant Missense_Mutation SNP A A C NOVEL P11_Rec Untested WXS Illumina HiSeq 180 95 195 0 ENST00000309235.5:c.1198A>C p.Ile400Leu p.I400L ENST00000309235 NM_133464.2 400 Att/Ctt 0 +ASB5 UCSF GRCh37 4 177142715 177142715 + missense_variant Missense_Mutation SNP A A G NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 97 86 133 0 ENST00000296525.3:c.421T>C p.Phe141Leu p.F141L ENST00000296525 NM_080874.3 141 Ttc/Ctc 0 +ATRX UCSF GRCh37 X 76939908 76939920 + frameshift_variant Frame_Shift_Del DEL ACATGCAGTGACC ACATGCAGTGACC - NOVEL P12_Pri Untested WXS Illumina HiSeq 116 0 ENST00000373344.5:c.828_840del p.Val277ThrfsTer7 p.V277Tfs*7 ENST00000373344 NM_000489.3 276 ttGGTCACTGCATGT/tt 0 +C7orf57 UCSF GRCh37 7 48086205 48086205 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P12_Pri Untested WXS Illumina HiSeq 6 0 ENST00000348904.3:c.506del p.Lys169SerfsTer2 p.K169Sfs*2 ENST00000348904 NM_001100159.2 167 Aaa/aa 0 +CAND1 UCSF GRCh37 12 67686492 67686492 + synonymous_variant Silent SNP A A G NOVEL P12_Pri Untested WXS Illumina HiSeq 129 94 156 0 ENST00000545606.1:c.303A>G p.Gln101= p.Q101= ENST00000545606 NM_018448.3 101 caA/caG 0 +CHST8 UCSF GRCh37 19 34263267 34263267 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 8 9 63 0 ENST00000262622.4:c.574G>A p.Val192Met p.V192M ENST00000262622 NM_022467.3 192 Gtg/Atg 0 +COL6A3 UCSF GRCh37 2 238253159 238253159 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Pri Untested WXS Illumina HiSeq 123 98 164 0 ENST00000295550.4:c.7502G>A p.Arg2501His p.R2501H ENST00000295550 NM_004369.3 2501 cGt/cAt 0 +DGAT2L6 UCSF GRCh37 X 69424267 69424268 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P12_Pri Untested WXS Illumina HiSeq 39 0 ENST00000333026.3:c.766dup p.Ile256AsnfsTer42 p.I256Nfs*42 ENST00000333026 NM_198512.1 254 aaa/aAaa 0 +DNMT1 UCSF GRCh37 19 10270707 10270742 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACTGTTTTGGCGCGAGCCATTTTTTTCTCCGTTCTG ACTGTTTTGGCGCGAGCCATTTTTTTCTCCGTTCTG TTTGTTTGGGCGGGAGCCATTTTTTTCTCCGTTCT NOVEL P12_Pri Untested WXS Illumina HiSeq 6 0 ENST00000340748.4:c.996-3_1028delinsAGAACGGAGAAAAAAATGGCTCCCGCCCAAACAAA p.X332_splice ENST00000340748 0 +FAF2 UCSF GRCh37 5 175927025 175927025 + missense_variant Missense_Mutation SNP A A G NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 102 67 142 0 ENST00000261942.6:c.1033A>G p.Arg345Gly p.R345G ENST00000261942 NM_014613.2 345 Agg/Ggg 0 +GPC2 UCSF GRCh37 7 99773267 99773267 + synonymous_variant Silent SNP G G C NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 41 33 71 0 ENST00000292377.2:c.576C>G p.Leu192= p.L192= ENST00000292377 NM_152742.1 192 ctC/ctG 0 +IARS UCSF GRCh37 9 95040528 95040528 + synonymous_variant Silent SNP T T C NOVEL P12_Pri Untested WXS Illumina HiSeq 143 113 180 0 ENST00000375643.3:c.786A>G p.Arg262= p.R262= ENST00000375643 NM_013417.3 262 agA/agG 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Pri somatic WXS Sanger Illumina HiSeq 91 85 125 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIF25 UCSF GRCh37 6 168430348 168430348 + missense_variant Missense_Mutation SNP A A T 1000g2010nov_all_0.200,1000g2011may_all_0.2270,snp132_rs4708626 P12_Pri Untested WXS Illumina HiSeq 87 10 75 1 ENST00000443060.2:c.83A>T p.Lys28Met p.K28M ENST00000443060 28 aAg/aTg 0 +ODZ4 UCSF GRCh37 11 78437125 78437125 + splice_region_variant,synonymous_variant Splice_Region SNP A A G NOVEL P12_Pri Untested WXS Illumina HiSeq 208 105 203 0 ENST00000278550.7:c.3549T>C p.Ser1183= p.S1183= ENST00000278550 NM_001098816.2 1183 agT/agC 0 +PI4KA UCSF GRCh37 22 21065645 21065645 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.330,1000g2011may_all_0.3814,snp132_rs1135934 P12_Pri Untested WXS Illumina HiSeq 33 4 34 1 ENST00000255882.6:c.5907T>C p.Gly1969= p.G1969= ENST00000255882 NM_058004.3 1969 ggT/ggC 0 +PIEZO2 UCSF GRCh37 18 10758061 10758061 + stop_gained Nonsense_Mutation SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 136 101 193 0 ENST00000503781.3:c.3754C>T p.Arg1252Ter p.R1252* ENST00000503781 NM_022068.2 1252 Cga/Tga 0 +PMEL UCSF GRCh37 12 56351767 56351767 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 91 63 132 0 ENST00000449260.2:c.571C>T p.Arg191Cys p.R191C ENST00000449260 NM_001200054.1 191 Cgc/Tgc 0 +SAG UCSF GRCh37 2 234224735 234224735 + synonymous_variant Silent SNP G G C NOVEL P12_Pri Untested WXS Illumina HiSeq 91 50 147 0 ENST00000409110.1:c.90G>C p.Leu30= p.L30= ENST00000409110 NM_000541.4 30 ctG/ctC 0 +SEZ6L2 UCSF GRCh37 16 29900024 29900024 + synonymous_variant Silent SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 48 10 41 1 ENST00000308713.5:c.876C>T p.Phe292= p.F292= ENST00000308713 NM_001114099.2 292 ttC/ttT 0 +SLC38A4 UCSF GRCh37 12 47186817 47186817 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 135 78 178 0 ENST00000447411.1:c.38C>T p.Pro13Leu p.P13L ENST00000447411 NM_001143824.1 13 cCa/cTa 0 +SLC7A2 UCSF GRCh37 8 17401018 17401018 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Pri Untested WXS Illumina HiSeq 82 70 103 0 ENST00000004531.10:c.290G>A p.Gly97Glu p.G97E ENST00000004531 NM_001164771.1 97 gGg/gAg 0 +TP53 UCSF GRCh37 17 7578406 7578406 + missense_variant Missense_Mutation SNP C C T snp132_rs28934578 P12_Pri somatic WXS Sanger Illumina HiSeq 10 100 87 0 ENST00000269305.4:c.524G>A p.Arg175His p.R175H ENST00000269305 NM_001126112.2 175 cGc/cAc 0 +ADAM20 UCSF GRCh37 14 70990780 70990780 + missense_variant Missense_Mutation SNP T T C NOVEL P12_Rec Untested WXS Illumina HiSeq 61 92 164 0 ENST00000256389.3:c.845A>G p.His282Arg p.H282R ENST00000256389 NM_003814.4 282 cAt/cGt 0 +ASB5 UCSF GRCh37 4 177142715 177142715 + missense_variant Missense_Mutation SNP A A G NOVEL P12_Rec somatic WXS Sanger Illumina HiSeq 101 70 133 0 ENST00000296525.3:c.421T>C p.Phe141Leu p.F141L ENST00000296525 NM_080874.3 141 Ttc/Ctc 0 +ATP8B1 UCSF GRCh37 18 55315829 55315829 + missense_variant Missense_Mutation SNP C C G NOVEL P12_Rec Untested WXS Illumina HiSeq 28 6 35 0 ENST00000536015.1:c.3647G>C p.Gly1216Ala p.G1216A ENST00000536015 NM_005603.4 1216 gGc/gCc 0 +ATP8B1 UCSF GRCh37 18 55315832 55315832 + missense_variant Missense_Mutation SNP C C A NOVEL P12_Rec Untested WXS Illumina HiSeq 25 7 34 0 ENST00000536015.1:c.3644G>T p.Arg1215Leu p.R1215L ENST00000536015 NM_005603.4 1215 cGg/cTg 0 +ATRX UCSF GRCh37 X 76939908 76939920 + frameshift_variant Frame_Shift_Del DEL ACATGCAGTGACC ACATGCAGTGACC - NOVEL P12_Rec Untested WXS Illumina HiSeq 86 0 ENST00000373344.5:c.828_840del p.Val277ThrfsTer7 p.V277Tfs*7 ENST00000373344 NM_000489.3 276 ttGGTCACTGCATGT/tt 0 +B3GNT3 UCSF GRCh37 19 17922618 17922618 + missense_variant Missense_Mutation SNP G G C NOVEL P12_Rec Untested WXS Illumina HiSeq 79 141 113 0 ENST00000318683.6:c.806G>C p.Gly269Ala p.G269A ENST00000318683 NM_014256.3 269 gGg/gCg 0 +CACNA1E UCSF GRCh37 1 181686272 181686272 + synonymous_variant Silent SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 137 124 155 0 ENST00000367573.2:c.1359C>T p.Asp453= p.D453= ENST00000367573 NM_001205293.1 453 gaC/gaT 0 +COL6A3 UCSF GRCh37 2 238253159 238253159 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 124 86 164 0 ENST00000295550.4:c.7502G>A p.Arg2501His p.R2501H ENST00000295550 NM_004369.3 2501 cGt/cAt 0 +DGAT2L6 UCSF GRCh37 X 69424267 69424268 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P12_Rec Untested WXS Illumina HiSeq 30 0 ENST00000333026.3:c.766dup p.Ile256AsnfsTer42 p.I256Nfs*42 ENST00000333026 NM_198512.1 254 aaa/aAaa 0 +EVX2 UCSF GRCh37 2 176945393 176945393 + synonymous_variant Silent SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 7 10 14 0 ENST00000308618.4:c.873C>T p.Gly291= p.G291= ENST00000308618 NM_001080458.1 291 ggC/ggT 0 +GFPT2 UCSF GRCh37 5 179755331 179755331 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 119 20 56 0 ENST00000253778.8:c.542C>T p.Ala181Val p.A181V ENST00000253778 NM_005110.2 181 gCa/gTa 0 +GIPC2 UCSF GRCh37 1 78560731 78560731 + synonymous_variant Silent SNP T T C NOVEL P12_Rec Untested WXS Illumina HiSeq 158 87 172 0 ENST00000370759.3:c.522T>C p.Arg174= p.R174= ENST00000370759 NM_017655.4 174 cgT/cgC 0 +IARS UCSF GRCh37 9 95040528 95040528 + synonymous_variant Silent SNP T T C NOVEL P12_Rec Untested WXS Illumina HiSeq 126 104 180 0 ENST00000375643.3:c.786A>G p.Arg262= p.R262= ENST00000375643 NM_013417.3 262 agA/agG 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Rec somatic WXS Sanger Illumina HiSeq 75 63 125 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KBTBD5 UCSF GRCh37 3 42728091 42728091 + synonymous_variant Silent SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 123 24 108 0 ENST00000287777.4:c.981C>T p.Gly327= p.G327= ENST00000287777 NM_152393.3 327 ggC/ggT 0 +KIAA0430 UCSF GRCh37 16 15727556 15727556 + missense_variant Missense_Mutation SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 115 101 173 0 ENST00000396368.3:c.1151G>A p.Gly384Asp p.G384D ENST00000396368 NM_001184998.1 384 gGc/gAc 0 +MRC2 UCSF GRCh37 17 60744152 60744152 + synonymous_variant Silent SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 15 15 29 0 ENST00000303375.5:c.894C>T p.Ile298= p.I298= ENST00000303375 NM_006039.4 298 atC/atT 0 +PIEZO2 UCSF GRCh37 18 10758061 10758061 + stop_gained Nonsense_Mutation SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 153 99 193 0 ENST00000503781.3:c.3754C>T p.Arg1252Ter p.R1252* ENST00000503781 NM_022068.2 1252 Cga/Tga 0 +PITX2 UCSF GRCh37 4 111553569 111553569 + synonymous_variant Silent SNP C C G NOVEL P12_Rec Untested WXS Illumina HiSeq 94 19 85 0 ENST00000354925.2:c.114G>C p.Thr38= p.T38= ENST00000354925 NM_001204397.1 38 acG/acC 0 +PMEL UCSF GRCh37 12 56351767 56351767 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 82 73 132 0 ENST00000449260.2:c.571C>T p.Arg191Cys p.R191C ENST00000449260 NM_001200054.1 191 Cgc/Tgc 0 +SLC7A2 UCSF GRCh37 8 17401018 17401018 + missense_variant Missense_Mutation SNP G G A NOVEL P12_Rec Untested WXS Illumina HiSeq 61 64 103 0 ENST00000004531.10:c.290G>A p.Gly97Glu p.G97E ENST00000004531 NM_001164771.1 97 gGg/gAg 0 +SMARCA4 UCSF GRCh37 19 11132549 11132549 + missense_variant Missense_Mutation SNP G G C NOVEL P12_Rec somatic WXS Sanger Illumina HiSeq 46 86 75 0 ENST00000344626.4:c.2765G>C p.Trp922Ser p.W922S ENST00000344626 NM_003072.3 922 tGg/tCg 0 +SSPO UCSF GRCh37 7 149490407 149490407 + non_coding_transcript_exon_variant RNA SNP G G A 1000g2011may_all_0.0039 P12_Rec Untested WXS Illumina HiSeq 15 7 23 0 ENST00000378016.2:n.5883G>A *1961* ENST00000378016 0 +TCHP UCSF GRCh37 12 110346455 110346455 + missense_variant Missense_Mutation SNP A A G snp132_rs78378786 P12_Rec Untested WXS Illumina HiSeq 18 4 28 1 ENST00000312777.5:c.764A>G p.Glu255Gly p.E255G ENST00000312777 NM_032300.4 255 gAg/gGg 0 +TMTC1 UCSF GRCh37 12 29920865 29920865 + missense_variant Missense_Mutation SNP A A C NOVEL P12_Rec Untested WXS Illumina HiSeq 121 15 130 0 ENST00000539277.1:c.446T>G p.Leu149Trp p.L149W ENST00000539277 NM_001193451.1 149 tTg/tGg 0 +TP53 UCSF GRCh37 17 7578406 7578406 + missense_variant Missense_Mutation SNP C C T snp132_rs28934578 P12_Rec somatic WXS Sanger Illumina HiSeq 9 99 87 0 ENST00000269305.4:c.524G>A p.Arg175His p.R175H ENST00000269305 NM_001126112.2 175 cGc/cAc 0 +WDFY3 UCSF GRCh37 4 85605229 85605229 + missense_variant Missense_Mutation SNP T T C NOVEL P12_Rec Untested WXS Illumina HiSeq 90 77 121 0 ENST00000295888.4:c.9593A>G p.Asn3198Ser p.N3198S ENST00000295888 NM_014991.4 3198 aAt/aGt 0 +ZBTB45 UCSF GRCh37 19 59028912 59028912 + synonymous_variant Silent SNP C C T NOVEL P12_Rec Untested WXS Illumina HiSeq 58 51 74 0 ENST00000594051.1:c.129G>A p.Ser43= p.S43= ENST00000594051 43 tcG/tcA 0 +AIM2 UCSF GRCh37 1 159032487 159032488 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000368130.4:c.1027dup p.Thr343AsnfsTer5 p.T343Nfs*5 ENST00000368130 NM_004833.1 342 -/A 0 +ASH1L UCSF GRCh37 1 155308000 155308000 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P13_Pri Untested WXS Illumina HiSeq 8 0 ENST00000392403.3:c.8683delA p.Thr2895GlnfsTer44 p.T2895Qfs*44 ENST00000392403 NM_018489.2 2895 Aca/ca 0 +ATRX UCSF GRCh37 X 76918952 76918955 + frameshift_variant Frame_Shift_Del DEL CAGT CAGT - NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 33 0 ENST00000373344.5:c.4036_4039del p.Thr1346Ter p.T1346* ENST00000373344 NM_000489.3 1346 ACTGtg/tg 0 +CDC7 UCSF GRCh37 1 91967357 91967357 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000428239.1:c.92delA p.Asn31ThrfsTer51 p.N31Tfs*51 ENST00000428239 NM_001134420.1 28 ttA/tt 0 +CNOT1 UCSF GRCh37 16 58580377 58580377 + missense_variant Missense_Mutation SNP A A C NOVEL P13_Pri Untested WXS Illumina HiSeq 110 21 126 1 ENST00000317147.5:c.3854T>G p.Val1285Gly p.V1285G ENST00000317147 NM_016284.4 1285 gTt/gGt 0 +CNOT1 UCSF GRCh37 16 58612662 58612662 + missense_variant Missense_Mutation SNP T T C snp132_rs112226008 P13_Pri Untested WXS Illumina HiSeq 115 58 147 0 ENST00000317147.5:c.1525A>G p.Ile509Val p.I509V ENST00000317147 NM_016284.4 509 Att/Gtt 0 +COL12A1 UCSF GRCh37 6 75890724 75890724 + missense_variant Missense_Mutation SNP C C A NOVEL P13_Pri Untested WXS Illumina HiSeq 99 38 171 0 ENST00000322507.8:c.2095G>T p.Val699Phe p.V699F ENST00000322507 NM_004370.5 699 Gtc/Ttc 0 +CR2 UCSF GRCh37 1 207643301 207643301 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 108 40 154 0 ENST00000367057.3:c.1079G>A p.Arg360Gln p.R360Q ENST00000367057 NM_001006658.2 360 cGa/cAa 0 +DYNC1I2 UCSF GRCh37 2 172549339 172549339 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P13_Pri Untested WXS Illumina HiSeq 7 0 ENST00000397119.3:c.169delA p.Arg57GlyfsTer13 p.R57Gfs*13 ENST00000397119 NM_001378.2 54 gAa/ga 0 +ELL2 UCSF GRCh37 5 95231362 95231362 + missense_variant Missense_Mutation SNP G G C NOVEL P13_Pri Untested WXS Illumina HiSeq 65 24 72 0 ENST00000237853.4:c.1559C>G p.Pro520Arg p.P520R ENST00000237853 NM_012081.5 520 cCt/cGt 0 +FAR2 UCSF GRCh37 12 29450110 29450110 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000536681.3:c.529delA p.Ile177SerfsTer8 p.I177Sfs*8 ENST00000536681 NM_001271783.1 174 ccA/cc 0 +FGF12 UCSF GRCh37 3 191888444 191888444 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P13_Pri Untested WXS Illumina HiSeq 132 52 164 0 ENST00000454309.2:c.416A>G p.Asp139Gly p.D139G ENST00000454309 NM_021032.4 139 gAt/gGt 0 +FMN2 UCSF GRCh37 1 240371223 240371223 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.149 P13_Pri Untested WXS Illumina HiSeq 12 4 18 0 ENST00000319653.9:c.3111C>T p.Pro1037= p.P1037= ENST00000319653 NM_020066.4 1037 ccC/ccT 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G C NOVEL P13_Pri Untested WXS Illumina HiSeq 86 33 136 0 ENST00000345146.2:c.394C>G p.Arg132Gly p.R132G ENST00000345146 NM_005896.2 132 Cgt/Ggt 0 +INTU UCSF GRCh37 4 128564702 128564702 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 174 37 199 0 ENST00000335251.6:c.173G>A p.Ser58Asn p.S58N ENST00000335251 NM_015693.3 58 aGt/aAt 0 +KLF17 UCSF GRCh37 1 44595246 44595246 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P13_Pri Untested WXS Illumina HiSeq 7 0 ENST00000372299.3:c.307del p.Gln103LysfsTer9 p.Q103Kfs*9 ENST00000372299 NM_173484.3 101 tgC/tg 0 +MUC5B UCSF GRCh37 11 1253980 1253980 + missense_variant Missense_Mutation SNP A A G 1000g2010nov_all_0.103,snp132_rs115853043 P13_Pri Untested WXS Illumina HiSeq 11 5 19 1 ENST00000529681.1:c.2045A>G p.Asp682Gly p.D682G ENST00000529681 NM_002458.2 682 gAc/gGc 0 +PCLO UCSF GRCh37 7 82581498 82581499 + inframe_insertion In_Frame_Ins INS - - TCT NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000333891.9:c.8770_8771insAGA p.Ile2923_Ile2924insLys p.I2923_I2924insK ENST00000333891 NM_033026.5 2924 ata/aAGAta 0 +PRDM9 UCSF GRCh37 5 23510029 23510029 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 77 20 101 0 ENST00000296682.3:c.194G>A p.Gly65Asp p.G65D ENST00000296682 NM_020227.2 65 gGt/gAt 0 +PZP UCSF GRCh37 12 9349246 9349246 + synonymous_variant Silent SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 235 35 221 0 ENST00000261336.2:c.903C>T p.His301= p.H301= ENST00000261336 NM_002864.2 301 caC/caT 0 +SEMA4B UCSF GRCh37 15 90771680 90771680 + synonymous_variant Silent SNP C C T NOVEL P13_Pri Untested WXS Illumina HiSeq 55 24 94 0 ENST00000411539.2:c.2319C>T p.Asn773= p.N773= ENST00000411539 NM_198925.2 773 aaC/aaT 0 +SHROOM3 UCSF GRCh37 4 77675759 77675759 + stop_gained Nonsense_Mutation SNP C C T NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 45 22 101 0 ENST00000296043.6:c.4123C>T p.Arg1375Ter p.R1375* ENST00000296043 NM_020859.3 1375 Cga/Tga 0 +SLFN13 UCSF GRCh37 17 33771784 33771784 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.015,1000g2011may_all_0.0426,snp132_rs78359177 P13_Pri Untested WXS Illumina HiSeq 146 67 188 0 ENST00000285013.6:c.916G>C p.Glu306Gln p.E306Q ENST00000285013 NM_144682.5 306 Gag/Cag 0 +TKTL2 UCSF GRCh37 4 164394416 164394416 + synonymous_variant Silent SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 110 18 145 0 ENST00000280605.3:c.471C>T p.Gly157= p.G157= ENST00000280605 NM_032136.4 157 ggC/ggT 0 +TP53 UCSF GRCh37 17 7579370 7579370 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 41 0 ENST00000269305.4:c.317del p.Ser106ThrfsTer17 p.S106Tfs*17 ENST00000269305 NM_001126112.2 106 aGc/ac 0 +TP53 UCSF GRCh37 17 7577515 7577516 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P13_Pri somatic WXS Sanger Illumina HiSeq 11 0 ENST00000269305.4:c.766dup p.Thr256AsnfsTer8 p.T256Nfs*8 ENST00000269305 NM_001126112.2 255 -/A 0 +TRIO UCSF GRCh37 5 14389501 14389503 + inframe_deletion In_Frame_Del DEL ATA ATA - NOVEL P13_Pri Untested WXS Illumina HiSeq 8 0 ENST00000344204.4:c.4056_4058del p.Asn1353del p.N1353del ENST00000344204 NM_007118.2 1351 cATAat/cat 0 +TTC28 UCSF GRCh37 22 28501647 28501647 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Pri Untested WXS Illumina HiSeq 103 65 194 0 ENST00000397906.2:c.2927C>T p.Ala976Val p.A976V ENST00000397906 NM_001145418.1 976 gCc/gTc 0 +UBE2J2 UCSF GRCh37 1 1191458 1191459 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P13_Pri Untested WXS Illumina HiSeq 16 0 ENST00000400930.4:c.509_510del p.Lys170SerfsTer4 p.K170Sfs*4 ENST00000400930 NM_194315.1 170 aAA/a 0 +ZRANB3 UCSF GRCh37 2 136148382 136148396 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region DEL ACCATACACCTGGAA ACCATACACCTGGAA CCCAAACCCCTGG NOVEL P13_Pri Untested WXS Illumina HiSeq 6 0 ENST00000264159.6:c.162-6_170delinsCCAGGGGTTTGGG p.X54_splice ENST00000264159 NM_032143.2 0 +ATRX UCSF GRCh37 X 76918952 76918955 + frameshift_variant Frame_Shift_Del DEL CAGT CAGT - NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 35 0 ENST00000373344.5:c.4036_4039del p.Thr1346Ter p.T1346* ENST00000373344 NM_000489.3 1346 ACTGtg/tg 0 +CCDC99 UCSF GRCh37 5 169021488 169021488 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P13_Rec Untested WXS Illumina HiSeq 17 0 ENST00000265295.4:c.774del p.Phe258LeufsTer18 p.F258Lfs*18 ENST00000265295 NM_017785.4 258 Ttt/tt 0 +CNOT1 UCSF GRCh37 16 58612662 58612662 + missense_variant Missense_Mutation SNP T T C snp132_rs112226008 P13_Rec Untested WXS Illumina HiSeq 93 42 147 0 ENST00000317147.5:c.1525A>G p.Ile509Val p.I509V ENST00000317147 NM_016284.4 509 Att/Gtt 0 +COL12A1 UCSF GRCh37 6 75890724 75890724 + missense_variant Missense_Mutation SNP C C A NOVEL P13_Rec Untested WXS Illumina HiSeq 113 47 171 0 ENST00000322507.8:c.2095G>T p.Val699Phe p.V699F ENST00000322507 NM_004370.5 699 Gtc/Ttc 0 +CR2 UCSF GRCh37 1 207643301 207643301 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 111 40 154 0 ENST00000367057.3:c.1079G>A p.Arg360Gln p.R360Q ENST00000367057 NM_001006658.2 360 cGa/cAa 0 +ELL2 UCSF GRCh37 5 95231362 95231362 + missense_variant Missense_Mutation SNP G G C NOVEL P13_Rec Untested WXS Illumina HiSeq 70 17 72 0 ENST00000237853.4:c.1559C>G p.Pro520Arg p.P520R ENST00000237853 NM_012081.5 520 cCt/cGt 0 +FGF12 UCSF GRCh37 3 191888444 191888444 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P13_Rec Untested WXS Illumina HiSeq 115 32 164 0 ENST00000454309.2:c.416A>G p.Asp139Gly p.D139G ENST00000454309 NM_021032.4 139 gAt/gGt 0 +GLTSCR1 UCSF GRCh37 19 48205548 48205548 + missense_variant Missense_Mutation SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 19 9 23 0 ENST00000396720.3:c.4559C>T p.Ala1520Val p.A1520V ENST00000396720 NM_015711.3 1520 gCg/gTg 0 +HACE1 UCSF GRCh37 6 105219151 105219151 + missense_variant Missense_Mutation SNP C C G NOVEL P13_Rec Untested WXS Illumina HiSeq 112 22 136 0 ENST00000262903.4:c.2128G>C p.Val710Leu p.V710L ENST00000262903 NM_020771.3 710 Gtt/Ctt 0 +IDH1 UCSF GRCh37 2 209113113 209113113 + missense_variant Missense_Mutation SNP G G C NOVEL P13_Rec Untested WXS Illumina HiSeq 69 27 136 0 ENST00000345146.2:c.394C>G p.Arg132Gly p.R132G ENST00000345146 NM_005896.2 132 Cgt/Ggt 0 +INTU UCSF GRCh37 4 128564702 128564702 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 154 33 199 0 ENST00000335251.6:c.173G>A p.Ser58Asn p.S58N ENST00000335251 NM_015693.3 58 aGt/aAt 0 +LAMA1 UCSF GRCh37 18 6971860 6971860 + missense_variant Missense_Mutation SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 139 34 177 0 ENST00000389658.3:c.6895G>A p.Gly2299Arg p.G2299R ENST00000389658 NM_005559.3 2299 Gga/Aga 0 +LCA5L UCSF GRCh37 21 40777928 40777928 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0015 P13_Rec Untested WXS Illumina HiSeq 86 12 102 0 ENST00000358268.2:c.1893G>A p.Ser631= p.S631= ENST00000358268 631 tcG/tcA 0 +MPHOSPH10 UCSF GRCh37 2 71371569 71371571 + inframe_deletion In_Frame_Del DEL AGA AGA - NOVEL P13_Rec Untested WXS Illumina HiSeq 7 0 ENST00000244230.2:c.1465_1467del p.Glu489del p.E489del ENST00000244230 NM_005791.2 486 gcAGAa/gca 0 +MYO18B UCSF GRCh37 22 26194037 26194037 + missense_variant Missense_Mutation SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 62 13 108 0 ENST00000335473.7:c.2494C>T p.His832Tyr p.H832Y ENST00000335473 NM_032608.5 832 Cac/Tac 0 +MYO7A UCSF GRCh37 11 76905469 76905469 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 50 7 61 0 ENST00000409709.3:c.4223G>A p.Arg1408His p.R1408H ENST00000409709 NM_000260.3 1408 cGc/cAc 0 +MYO9B UCSF GRCh37 19 17311626 17311626 + synonymous_variant Silent SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 124 14 153 0 ENST00000595618.1:c.4551C>T p.Phe1517= p.F1517= ENST00000595618 NM_001130065.1 1517 ttC/ttT 0 +NWD1 UCSF GRCh37 19 16872863 16872863 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 101 15 102 0 ENST00000524140.2:c.2047G>A p.Asp683Asn p.D683N ENST00000524140 NM_001007525.3 683 Gac/Aac 0 +PRDM9 UCSF GRCh37 5 23510029 23510029 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 58 26 101 0 ENST00000296682.3:c.194G>A p.Gly65Asp p.G65D ENST00000296682 NM_020227.2 65 gGt/gAt 0 +PROL1 UCSF GRCh37 4 71275502 71275502 + missense_variant Missense_Mutation SNP A A G NOVEL P13_Rec Untested WXS Illumina HiSeq 133 19 168 0 ENST00000399575.2:c.457A>G p.Ile153Val p.I153V ENST00000399575 NM_021225.4 153 Atc/Gtc 0 +RBPJ UCSF GRCh37 4 26426014 26426017 + frameshift_variant Frame_Shift_Del DEL CAGA CAGA - NOVEL P13_Rec Untested WXS Illumina HiSeq 12 0 ENST00000342295.1:c.589_592delACAG p.Thr197LeufsTer8 p.T197Lfs*8 ENST00000342295 NM_005349.3 196 CAGAca/ca 0 +RIF1 UCSF GRCh37 2 152320028 152320028 + missense_variant Missense_Mutation SNP C C G NOVEL P13_Rec Untested WXS Illumina HiSeq 134 20 128 0 ENST00000243326.5:c.3994C>G p.Leu1332Val p.L1332V ENST00000243326 1332 Ctt/Gtt 0 +RPL35 UCSF GRCh37 9 127623796 127623798 + inframe_deletion In_Frame_Del DEL CTT CTT - NOVEL P13_Rec Untested WXS Illumina HiSeq 8 0 ENST00000348462.3:c.40_42del p.Lys14del p.K14del ENST00000348462 NM_007209.3 14 AAG/- 0 +SDK1 UCSF GRCh37 7 4153752 4153752 + synonymous_variant Silent SNP A A G NOVEL P13_Rec Untested WXS Illumina HiSeq 76 9 91 0 ENST00000404826.2:c.3669A>G p.Ser1223= p.S1223= ENST00000404826 NM_152744.3 1223 tcA/tcG 0 +SEMA4B UCSF GRCh37 15 90771680 90771680 + synonymous_variant Silent SNP C C T NOVEL P13_Rec Untested WXS Illumina HiSeq 78 27 94 0 ENST00000411539.2:c.2319C>T p.Asn773= p.N773= ENST00000411539 NM_198925.2 773 aaC/aaT 0 +SHROOM3 UCSF GRCh37 4 77675759 77675759 + stop_gained Nonsense_Mutation SNP C C T NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 64 12 101 0 ENST00000296043.6:c.4123C>T p.Arg1375Ter p.R1375* ENST00000296043 NM_020859.3 1375 Cga/Tga 0 +SLFN13 UCSF GRCh37 17 33771784 33771784 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.015,1000g2011may_all_0.0426,snp132_rs78359177 P13_Rec Untested WXS Illumina HiSeq 114 40 188 0 ENST00000285013.6:c.916G>C p.Glu306Gln p.E306Q ENST00000285013 NM_144682.5 306 Gag/Cag 0 +TP53 UCSF GRCh37 17 7579370 7579370 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 30 0 ENST00000269305.4:c.317del p.Ser106ThrfsTer17 p.S106Tfs*17 ENST00000269305 NM_001126112.2 106 aGc/ac 0 +TP53 UCSF GRCh37 17 7577515 7577516 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P13_Rec somatic WXS Sanger Illumina HiSeq 8 0 ENST00000269305.4:c.766dup p.Thr256AsnfsTer8 p.T256Nfs*8 ENST00000269305 NM_001126112.2 255 -/A 0 +TTC28 UCSF GRCh37 22 28501647 28501647 + missense_variant Missense_Mutation SNP G G A NOVEL P13_Rec Untested WXS Illumina HiSeq 125 63 194 0 ENST00000397906.2:c.2927C>T p.Ala976Val p.A976V ENST00000397906 NM_001145418.1 976 gCc/gTc 0 +UNC5C UCSF GRCh37 4 96163617 96163617 + missense_variant Missense_Mutation SNP C C G NOVEL P13_Rec Untested WXS Illumina HiSeq 69 11 81 0 ENST00000453304.1:c.1071G>C p.Leu357Phe p.L357F ENST00000453304 NM_003728.3 357 ttG/ttC 0 +ANKRD49 UCSF GRCh37 11 94230059 94230060 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P15_Pri Untested WXS Illumina HiSeq 6 0 ENST00000544612.1:c.208dup p.Met70AsnfsTer14 p.M70Nfs*14 ENST00000544612 NM_017704.2 67 gaa/gaAa 0 +AQP2 UCSF GRCh37 12 50344806 50344806 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 31 21 45 0 ENST00000199280.3:c.193G>A p.Ala65Thr p.A65T ENST00000199280 NM_000486.5 65 Gcc/Acc 0 +ATP2A3 UCSF GRCh37 17 3848013 3848013 + synonymous_variant Silent SNP A A C 1000g2010nov_all_0.333,1000g2011may_all_0.4766,snp132_rs1800911 P15_Pri Untested WXS Illumina HiSeq 17 7 12 0 ENST00000359983.3:c.1272T>G p.Ala424= p.A424= ENST00000359983 424 gcT/gcG 0 +C7orf41 UCSF GRCh37 7 30174773 30174773 + synonymous_variant Silent SNP C C G 1000g2010nov_all_0.152,1000g2011may_all_0.1580,snp132_rs73689406 P15_Pri Untested WXS Illumina HiSeq 11 18 9 0 ENST00000324453.8:c.21C>G p.Ala7= p.A7= ENST00000324453 NM_152793.2 7 gcC/gcG 0 +CCIN UCSF GRCh37 9 36170747 36170747 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0023 P15_Pri Untested WXS Illumina HiSeq 136 40 68 0 ENST00000335119.2:c.1248C>T p.Thr416= p.T416= ENST00000335119 NM_005893.2 416 acC/acT 0 +COL12A1 UCSF GRCh37 6 75892915 75892915 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 166 62 103 0 ENST00000322507.8:c.1742G>A p.Arg581His p.R581H ENST00000322507 NM_004370.5 581 cGc/cAc 0 +EDEM3 UCSF GRCh37 1 184692968 184692999 + coding_sequence_variant,intron_variant Frame_Shift_Ins INS TCAAGAGCTTTTCTGGCATATTCCTGTAATTT TCAAGAGCTTTTCTGGCATATTCCTGTAATTT AAAAAAGGTTTTTTGGCATATTCCTTTAATTTA NOVEL P15_Pri Untested WXS Illumina HiSeq 6 0 ENST00000318130.8:c.748-9_770delinsTAAATTAAAGGAATATGCCAAAAAACCTTTTTT *250fs* ENST00000318130 NM_025191.3 0 +FRMPD4 UCSF GRCh37 X 12734265 12734265 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 217 38 125 0 ENST00000380682.1:c.1687G>A p.Glu563Lys p.E563K ENST00000380682 NM_014728.3 563 Gaa/Aaa 0 +HIST1H4D UCSF GRCh37 6 26189132 26189132 + missense_variant Missense_Mutation SNP A A T NOVEL P15_Pri Untested WXS Illumina HiSeq 126 52 75 0 ENST00000340756.2:c.173T>A p.Val58Glu p.V58E ENST00000340756 NM_003539.3 58 gTg/gAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 90 53 57 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KCNMA1 UCSF GRCh37 10 78729786 78729786 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P15_Pri Untested WXS Illumina HiSeq 7 0 ENST00000404857.1:c.2132delA p.Lys711SerfsTer17 p.K711Sfs*17 ENST00000404857 NM_001161353.1 711 aAg/ag 0 +KRTAP5-5 UCSF GRCh37 11 1651608 1651637 + inframe_deletion In_Frame_Del DEL AAGCCTTACTGCTGCCAGTCCAGCTGCTGT AAGCCTTACTGCTGCCAGTCCAGCTGCTGT - NOVEL P15_Pri Untested WXS Illumina HiSeq 6 0 ENST00000399676.2:c.543_572del p.Tyr192_Pro201del p.Y192_P201del ENST00000399676 NM_001001480.2 180 AAGCCTTACTGCTGCCAGTCCAGCTGCTGT/- 0 +MUC5B UCSF GRCh37 11 1251743 1251743 + synonymous_variant Silent SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 9 8 20 0 ENST00000529681.1:c.1383C>T p.Thr461= p.T461= ENST00000529681 NM_002458.2 461 acC/acT 0 +NCAM1 UCSF GRCh37 11 113078099 113078102 + splice_donor_variant,coding_sequence_variant Splice_Site DEL AAGT AAGT - NOVEL P15_Pri Untested WXS Illumina HiSeq 18 0 ENST00000524665.1:c.923+2_923+5del p.X308_splice ENST00000524665 NM_000615.6 308 0 +OR6C68 UCSF GRCh37 12 55887087 55887087 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 116 24 82 0 ENST00000548615.1:c.926G>A p.Arg309His p.R309H ENST00000548615 NM_001005519.2 309 cGt/cAt 0 +PLA2G4A UCSF GRCh37 1 186948489 186948489 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Pri Untested WXS Illumina HiSeq 145 36 101 0 ENST00000367466.3:c.2003T>C p.Phe668Ser p.F668S ENST00000367466 NM_024420.2 668 tTt/tCt 0 +PLXNA1 UCSF GRCh37 3 126751380 126751380 + missense_variant Missense_Mutation SNP C C A NOVEL P15_Pri Untested WXS Illumina HiSeq 63 16 45 0 ENST00000393409.2:c.5382C>A p.Asp1794Glu p.D1794E ENST00000393409 NM_032242.3 1794 gaC/gaA 0 +PRG4 UCSF GRCh37 1 186282886 186282886 + synonymous_variant Silent SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 131 32 115 0 ENST00000445192.2:c.4191C>T p.Ser1397= p.S1397= ENST00000445192 NM_005807.3 1397 tcC/tcT 0 +PRR21 UCSF GRCh37 2 240981556 240981556 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 25 4 15 1 ENST00000408934.1:c.844G>A p.Gly282Ser p.G282S ENST00000408934 NM_001080835.1 282 Ggc/Agc 0 +PRR21 UCSF GRCh37 2 240981526 240981526 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 39 5 35 1 ENST00000408934.1:c.874C>T p.Pro292Ser p.P292S ENST00000408934 NM_001080835.1 292 Ccc/Tcc 0 +RBM19 UCSF GRCh37 12 114282578 114282578 + synonymous_variant Silent SNP G G A NOVEL P15_Pri Untested WXS Illumina HiSeq 53 7 40 1 ENST00000545145.2:c.2680C>T p.Leu894= p.L894= ENST00000545145 NM_001146699.1 894 Ctg/Ttg 0 +SAMD9L UCSF GRCh37 7 92763519 92763519 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 195 40 144 0 ENST00000318238.4:c.1766G>A p.Arg589Gln p.R589Q ENST00000318238 NM_152703.2 589 cGa/cAa 0 +SIGLEC1 UCSF GRCh37 20 3675563 3675563 + stop_gained Nonsense_Mutation SNP C C T NOVEL P15_Pri somatic WXS Sanger Illumina HiSeq 41 20 33 0 ENST00000344754.4:c.2691G>A p.Trp897Ter p.W897* ENST00000344754 NM_023068.3 897 tgG/tgA 0 +SLCO1B3 UCSF GRCh37 12 21028267 21028267 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P15_Pri Untested WXS Illumina HiSeq 6 0 ENST00000381545.3:c.833delT p.Phe278SerfsTer22 p.F278Sfs*22 ENST00000381545 NM_019844.3 276 Ttt/tt 0 +SMARCA4 UCSF GRCh37 19 11144027 11144027 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Pri somatic WXS Sanger Illumina HiSeq 88 24 67 0 ENST00000344626.4:c.3608G>A p.Arg1203His p.R1203H ENST00000344626 NM_003072.3 1203 cGc/cAc 0 +SNX29 UCSF GRCh37 16 12162987 12162987 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P15_Pri Untested WXS Illumina HiSeq 119 22 84 0 ENST00000566228.1:c.1317C>T p.Tyr439= p.Y439= ENST00000566228 NM_032167.3 439 taC/taT 0 +ACPT UCSF GRCh37 19 51297752 51297752 + synonymous_variant Silent SNP C C A NOVEL P15_Rec Untested WXS Illumina HiSeq 22 3 46 0 ENST00000270593.1:c.900C>A p.Gly300= p.G300= ENST00000270593 NM_033068.2 300 ggC/ggA 0 +AKAP1 UCSF GRCh37 17 55195794 55195794 + synonymous_variant Silent SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 26 28 65 0 ENST00000337714.3:c.2553G>A p.Gly851= p.G851= ENST00000337714 NM_003488.3 851 ggG/ggA 0 +AQP2 UCSF GRCh37 12 50344806 50344806 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 22 21 45 0 ENST00000199280.3:c.193G>A p.Ala65Thr p.A65T ENST00000199280 NM_000486.5 65 Gcc/Acc 0 +ATP2A3 UCSF GRCh37 17 3848013 3848013 + synonymous_variant Silent SNP A A C 1000g2010nov_all_0.333,1000g2011may_all_0.4766,snp132_rs1800911 P15_Rec Untested WXS Illumina HiSeq 9 5 12 0 ENST00000359983.3:c.1272T>G p.Ala424= p.A424= ENST00000359983 424 gcT/gcG 0 +C7orf41 UCSF GRCh37 7 30174773 30174773 + synonymous_variant Silent SNP C C G 1000g2010nov_all_0.152,1000g2011may_all_0.1580,snp132_rs73689406 P15_Rec Untested WXS Illumina HiSeq 8 7 9 0 ENST00000324453.8:c.21C>G p.Ala7= p.A7= ENST00000324453 NM_152793.2 7 gcC/gcG 0 +CANX UCSF GRCh37 5 179143236 179143236 + synonymous_variant Silent SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 61 24 77 0 ENST00000247461.4:c.852C>T p.Pro284= p.P284= ENST00000247461 NM_001746.3 284 ccC/ccT 0 +CCDC11 UCSF GRCh37 18 47753978 47753978 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 84 44 79 0 ENST00000398545.4:c.1318C>T p.Arg440Cys p.R440C ENST00000398545 NM_145020.3 440 Cgc/Tgc 0 +CCDC150 UCSF GRCh37 2 197537116 197537116 + synonymous_variant Silent SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 70 35 96 0 ENST00000389175.4:c.984G>A p.Leu328= p.L328= ENST00000389175 NM_001080539.1 328 ttG/ttA 0 +CCIN UCSF GRCh37 9 36170747 36170747 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0023 P15_Rec Untested WXS Illumina HiSeq 73 57 68 0 ENST00000335119.2:c.1248C>T p.Thr416= p.T416= ENST00000335119 NM_005893.2 416 acC/acT 0 +CIC UCSF GRCh37 19 42799063 42799065 + inframe_deletion In_Frame_Del DEL AGA AGA - NOVEL P15_Rec somatic WXS Sanger Illumina HiSeq 16 0 ENST00000575354.2:c.4550_4552del p.Lys1517del p.K1517del ENST00000575354 NM_015125.3 1516 cAGAag/cag 0 +CLEC18A UCSF GRCh37 16 69988359 69988359 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.049,1000g2011may_all_0.1101,snp132_rs2549095 P15_Rec Untested WXS Illumina HiSeq 38 5 23 1 ENST00000288040.6:c.339A>G p.Leu113= p.L113= ENST00000288040 NM_001136214.2 113 ctA/ctG 0 +COL12A1 UCSF GRCh37 6 75892915 75892915 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 87 60 103 0 ENST00000322507.8:c.1742G>A p.Arg581His p.R581H ENST00000322507 NM_004370.5 581 cGc/cAc 0 +DNAH17 UCSF GRCh37 17 76481017 76481017 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 37 20 39 0 ENST00000389840.5:c.7540G>A p.Glu2514Lys p.E2514K ENST00000389840 2514 Gag/Aag 0 +ERBB4 UCSF GRCh37 2 212248672 212248672 + missense_variant Missense_Mutation SNP C C G NOVEL P15_Rec Untested WXS Illumina HiSeq 86 66 126 0 ENST00000342788.4:c.3595G>C p.Glu1199Gln p.E1199Q ENST00000342788 NM_005235.2 1199 Gag/Cag 0 +GIMAP7 UCSF GRCh37 7 150217197 150217197 + missense_variant Missense_Mutation SNP G G T NOVEL P15_Rec Untested WXS Illumina HiSeq 74 38 111 0 ENST00000313543.4:c.135G>T p.Lys45Asn p.K45N ENST00000313543 NM_153236.3 45 aaG/aaT 0 +HERC1 UCSF GRCh37 15 63954081 63954081 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Rec Untested WXS Illumina HiSeq 154 63 133 0 ENST00000443617.2:c.9041A>G p.Asn3014Ser p.N3014S ENST00000443617 NM_003922.3 3014 aAt/aGt 0 +HIST1H4D UCSF GRCh37 6 26189132 26189132 + missense_variant Missense_Mutation SNP A A T NOVEL P15_Rec Untested WXS Illumina HiSeq 59 45 75 0 ENST00000340756.2:c.173T>A p.Val58Glu p.V58E ENST00000340756 NM_003539.3 58 gTg/gAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 52 37 57 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGSF3 UCSF GRCh37 1 117146592 117146592 + missense_variant Missense_Mutation SNP C C G NOVEL P15_Rec Untested WXS Illumina HiSeq 25 4 50 0 ENST00000369483.1:c.1338G>C p.Glu446Asp p.E446D ENST00000369483 NM_001542.3 446 gaG/gaC 0 +KCND2 UCSF GRCh37 7 119915468 119915468 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Rec Untested WXS Illumina HiSeq 52 23 66 0 ENST00000331113.4:c.782T>C p.Val261Ala p.V261A ENST00000331113 NM_012281.2 261 gTc/gCc 0 +MLL3 UCSF GRCh37 7 151935894 151935894 + missense_variant Missense_Mutation SNP A A C NOVEL P15_Rec Untested WXS Illumina HiSeq 178 20 187 0 ENST00000262189.6:c.2550T>G p.His850Gln p.H850Q ENST00000262189 NM_170606.2 850 caT/caG 0 +NES UCSF GRCh37 1 156641394 156641394 + synonymous_variant Silent SNP A A C NOVEL P15_Rec Untested WXS Illumina HiSeq 94 51 121 0 ENST00000368223.3:c.2586T>G p.Pro862= p.P862= ENST00000368223 NM_006617.1 862 ccT/ccG 0 +PCDHB13 UCSF GRCh37 5 140595477 140595477 + synonymous_variant Silent SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 24 12 60 1 ENST00000341948.4:c.1782C>T p.Gly594= p.G594= ENST00000341948 NM_018933.2 594 ggC/ggT 0 +PLA2G4A UCSF GRCh37 1 186948489 186948489 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Rec Untested WXS Illumina HiSeq 67 42 101 0 ENST00000367466.3:c.2003T>C p.Phe668Ser p.F668S ENST00000367466 NM_024420.2 668 tTt/tCt 0 +PLS3 UCSF GRCh37 X 114869338 114869338 + missense_variant Missense_Mutation SNP T T C NOVEL P15_Rec Untested WXS Illumina HiSeq 120 42 110 0 ENST00000420625.2:c.728T>C p.Ile243Thr p.I243T ENST00000420625 NM_001136025.3 243 aTt/aCt 0 +PLXNA1 UCSF GRCh37 3 126751380 126751380 + missense_variant Missense_Mutation SNP C C A NOVEL P15_Rec Untested WXS Illumina HiSeq 35 27 45 0 ENST00000393409.2:c.5382C>A p.Asp1794Glu p.D1794E ENST00000393409 NM_032242.3 1794 gaC/gaA 0 +PRG4 UCSF GRCh37 1 186282886 186282886 + synonymous_variant Silent SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 74 73 115 0 ENST00000445192.2:c.4191C>T p.Ser1397= p.S1397= ENST00000445192 NM_005807.3 1397 tcC/tcT 0 +PSG11 UCSF GRCh37 19 43529085 43529085 + missense_variant Missense_Mutation SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 53 20 112 0 ENST00000401740.1:c.188C>T p.Thr63Ile p.T63I ENST00000401740 63 aCt/aTt 0 +RBM19 UCSF GRCh37 12 114282578 114282578 + synonymous_variant Silent SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 22 20 40 1 ENST00000545145.2:c.2680C>T p.Leu894= p.L894= ENST00000545145 NM_001146699.1 894 Ctg/Ttg 0 +SAMD9L UCSF GRCh37 7 92763519 92763519 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 84 69 144 0 ENST00000318238.4:c.1766G>A p.Arg589Gln p.R589Q ENST00000318238 NM_152703.2 589 cGa/cAa 0 +SIGLEC1 UCSF GRCh37 20 3675563 3675563 + stop_gained Nonsense_Mutation SNP C C T NOVEL P15_Rec somatic WXS Sanger Illumina HiSeq 21 17 33 0 ENST00000344754.4:c.2691G>A p.Trp897Ter p.W897* ENST00000344754 NM_023068.3 897 tgG/tgA 0 +SORD UCSF GRCh37 15 45361180 45361180 + missense_variant Missense_Mutation SNP A A T 1000g2010nov_all_0.196,1000g2011may_all_0.4705,snp132_rs1042079 P15_Rec Untested WXS Illumina HiSeq 19 5 32 1 ENST00000267814.9:c.716A>T p.Gln239Leu p.Q239L ENST00000267814 NM_003104.5 239 cAg/cTg 0 +TMEM132A UCSF GRCh37 11 60699305 60699305 + stop_gained Nonsense_Mutation SNP G G A NOVEL P15_Rec Untested WXS Illumina HiSeq 81 11 66 0 ENST00000005286.4:c.1164G>A p.Trp388Ter p.W388* ENST00000005286 NM_178031.2 388 tgG/tgA 0 +TMTC2 UCSF GRCh37 12 83251171 83251171 + missense_variant Missense_Mutation SNP A A G NOVEL P15_Rec Untested WXS Illumina HiSeq 47 36 68 0 ENST00000321196.3:c.466A>G p.Ile156Val p.I156V ENST00000321196 NM_152588.1 156 Att/Gtt 0 +VAV2 UCSF GRCh37 9 136662918 136662918 + missense_variant Missense_Mutation SNP C C T NOVEL P15_Rec Untested WXS Illumina HiSeq 16 8 36 0 ENST00000371850.3:c.850G>A p.Gly284Arg p.G284R ENST00000371850 NM_001134398.1 284 Ggg/Agg 0 +ANKRD30B UCSF GRCh37 18 14852419 14852419 + missense_variant Missense_Mutation SNP A A T NOVEL P16_Pri Untested WXS Illumina HiSeq 35 21 102 0 ENST00000358984.4:c.4119A>T p.Glu1373Asp p.E1373D ENST00000358984 NM_001145029.1 1373 gaA/gaT 0 +ATM UCSF GRCh37 11 108159724 108159724 + missense_variant Missense_Mutation SNP A A C NOVEL P16_Pri Untested WXS Illumina HiSeq 99 12 150 0 ENST00000278616.4:c.4130A>C p.Asn1377Thr p.N1377T ENST00000278616 NM_000051.3 1377 aAt/aCt 0 +ATRX UCSF GRCh37 X 76939906 76939907 + frameshift_variant Frame_Shift_Ins INS - - TTACATGCAGTGACCAAGTCCAACAAAGGCTCTGGGTGACAAATGTAGC NOVEL P16_Pri Untested WXS Illumina HiSeq 10 0 ENST00000373344.5:c.841_842insGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAA p.Asn281SerfsTer21 p.N281Sfs*21 ENST00000373344 NM_000489.3 281 aac/aGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAAac 0 +BLMH UCSF GRCh37 17 28614922 28614922 + missense_variant Missense_Mutation SNP G G C NOVEL P16_Pri Untested WXS Illumina HiSeq 77 21 127 0 ENST00000261714.6:c.365C>G p.Ala122Gly p.A122G ENST00000261714 NM_000386.3 122 gCc/gGc 0 +C10orf12 UCSF GRCh37 10 98744566 98744566 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 52 44 165 0 ENST00000286067.2:c.3419C>T p.Thr1140Met p.T1140M ENST00000286067 NM_015652.2 1140 aCg/aTg 0 +C17orf97 UCSF GRCh37 17 263652 263652 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.1126,snp132_rs111543298 P16_Pri Untested WXS Illumina HiSeq 40 7 56 1 ENST00000360127.6:c.1018G>A p.Glu340Lys p.E340K ENST00000360127 NM_001013672.4 340 Gag/Aag 0 +CRIPAK UCSF GRCh37 4 1388817 1388817 + missense_variant Missense_Mutation SNP C C G 1000g2011may_all_0.1284 P16_Pri Untested WXS Illumina HiSeq 90 11 25 1 ENST00000324803.4:c.518C>G p.Pro173Arg p.P173R ENST00000324803 NM_175918.3 173 cCa/cGa 0 +CRIPAK UCSF GRCh37 4 1388819 1388819 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 93 13 29 1 ENST00000324803.4:c.520T>C p.Cys174Arg p.C174R ENST00000324803 NM_175918.3 174 Tgt/Cgt 0 +CT47B1 UCSF GRCh37 X 120009392 120009392 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 31 6 9 0 ENST00000371311.3:c.133A>G p.Met45Val p.M45V ENST00000371311 NM_001145718.1 45 Atg/Gtg 0 +CTPS2 UCSF GRCh37 X 16627738 16627738 + synonymous_variant Silent SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 44 36 100 0 ENST00000443824.1:c.1617G>A p.Pro539= p.P539= ENST00000443824 NM_001144002.1 539 ccG/ccA 0 +CYP2D6 UCSF GRCh37 22 42524214 42524215 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P16_Pri Untested WXS Illumina HiSeq 6 0 ENST00000360608.5:c.805dup p.Arg269ProfsTer5 p.R269Pfs*5 ENST00000360608 NM_000106.5 268 -/C 0 +DIP2A UCSF GRCh37 21 47924280 47924280 + missense_variant Missense_Mutation SNP A A C NOVEL P16_Pri Untested WXS Illumina HiSeq 86 58 203 0 ENST00000417564.2:c.662A>C p.His221Pro p.H221P ENST00000417564 221 cAt/cCt 0 +EPB41L4B UCSF GRCh37 9 111979226 111979226 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 50 44 129 0 ENST00000374566.3:c.1609A>G p.Asn537Asp p.N537D ENST00000374566 NM_019114.3 537 Aac/Gac 0 +EPPK1 UCSF GRCh37 8 144940543 144940543 + synonymous_variant Silent SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 135 16 10 0 ENST00000525985.1:c.6879C>T p.Gly2293= p.G2293= ENST00000525985 NM_031308.2 2293 ggC/ggT 0 +GATA3 UCSF GRCh37 10 8115916 8115916 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 58 9 123 0 ENST00000346208.3:c.1262C>T p.Pro421Leu p.P421L ENST00000346208 421 cCg/cTg 0 +GBA3 UCSF GRCh37 4 22749378 22749378 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 93 11 235 0 ENST00000508166.1:c.746T>C p.Phe249Ser p.F249S ENST00000508166 NM_020973.4 249 tTc/tCc 0 +HLA-C UCSF GRCh37 6 31239602 31239602 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.030,1000g2011may_all_0.1058,snp132_rs1050441 P16_Pri Untested WXS Illumina HiSeq 14 3 9 0 ENST00000376228.5:c.117C>T p.Pro39= p.P39= ENST00000376228 NM_002117.5 39 ccC/ccT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 54 32 148 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIAA0319 UCSF GRCh37 6 24581174 24581174 + missense_variant Missense_Mutation SNP A A G NOVEL P16_Pri Untested WXS Illumina HiSeq 42 34 214 0 ENST00000378214.3:c.1259T>C p.Val420Ala p.V420A ENST00000378214 NM_014809.3 420 gTc/gCc 0 +KIAA1024 UCSF GRCh37 15 79748599 79748599 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 65 9 124 0 ENST00000305428.3:c.110G>A p.Arg37Gln p.R37Q ENST00000305428 NM_015206.2 37 cGg/cAg 0 +LARP7 UCSF GRCh37 4 113575231 113575231 + synonymous_variant Silent SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 51 33 114 0 ENST00000509061.1:c.1605C>T p.His535= p.H535= ENST00000509061 NM_001267039.1 535 caC/caT 0 +LRCH4 UCSF GRCh37 7 100179740 100179740 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 20 19 48 0 ENST00000310300.6:c.416G>A p.Arg139Lys p.R139K ENST00000310300 NM_002319.3 139 aGg/aAg 0 +MATN3 UCSF GRCh37 2 20205936 20205936 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 64 52 153 0 ENST00000407540.3:c.359C>T p.Thr120Met p.T120M ENST00000407540 NM_002381.4 120 aCg/aTg 0 +MYCBP2 UCSF GRCh37 13 77844582 77844582 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 46 31 140 0 ENST00000544440.2:c.923A>G p.Lys308Arg p.K308R ENST00000544440 308 aAg/aGg 0 +PGBD1 UCSF GRCh37 6 28269997 28269997 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 41 40 123 0 ENST00000405948.2:c.2366C>T p.Pro789Leu p.P789L ENST00000405948 NM_001184743.1 789 cCc/cTc 0 +PLD2 UCSF GRCh37 17 4722104 4722104 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 50 6 66 0 ENST00000263088.6:c.2159G>A p.Arg720His p.R720H ENST00000263088 NM_001243108.1 720 cGc/cAc 0 +RGS6 UCSF GRCh37 14 72818887 72818887 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Pri Untested WXS Illumina HiSeq 35 9 60 0 ENST00000553525.1:c.169C>T p.Pro57Ser p.P57S ENST00000553525 NM_001204424.1 57 Ccc/Tcc 0 +SCN9A UCSF GRCh37 2 167137077 167137077 + synonymous_variant Silent SNP T T A NOVEL P16_Pri Untested WXS Illumina HiSeq 70 9 132 0 ENST00000409672.1:c.2100A>T p.Pro700= p.P700= ENST00000409672 NM_002977.3 700 ccA/ccT 0 +SLC29A4 UCSF GRCh37 7 5340228 5340228 + missense_variant Missense_Mutation SNP A A C 1000g2010nov_all_0.042 P16_Pri Untested WXS Illumina HiSeq 47 6 35 1 ENST00000396872.3:c.1385A>C p.Tyr462Ser p.Y462S ENST00000396872 462 tAc/tCc 0 +SLC29A4 UCSF GRCh37 7 5340256 5340256 + synonymous_variant Silent SNP G G A NOVEL P16_Pri Untested WXS Illumina HiSeq 34 6 33 1 ENST00000396872.3:c.1413G>A p.Ala471= p.A471= ENST00000396872 471 gcG/gcA 0 +SMARCA4 UCSF GRCh37 19 11123695 11123695 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Pri somatic WXS Sanger Illumina HiSeq 38 9 81 0 ENST00000344626.4:c.2345G>A p.Gly782Asp p.G782D ENST00000344626 NM_003072.3 782 gGc/gAc 0 +TBC1D9 UCSF GRCh37 4 141578740 141578740 + synonymous_variant Silent SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 88 25 257 0 ENST00000442267.2:c.2148A>G p.Ala716= p.A716= ENST00000442267 NM_015130.2 716 gcA/gcG 0 +TH1L UCSF GRCh37 20 57565028 57565028 + missense_variant Missense_Mutation SNP G G C NOVEL P16_Pri Untested WXS Illumina HiSeq 20 27 63 0 ENST00000602795.1:c.827G>C p.Arg276Pro p.R276P ENST00000602795 NM_198976.2 276 cGc/cCc 0 +TP53 UCSF GRCh37 17 7578535 7578535 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Pri Untested WXS Illumina HiSeq 3 39 44 0 ENST00000269305.4:c.395A>G p.Lys132Arg p.K132R ENST00000269305 NM_001126112.2 132 aAg/aGg 0 +TPSD1 UCSF GRCh37 16 1306346 1306346 + missense_variant Missense_Mutation SNP C C G snp132_rs3865205 P16_Pri Untested WXS Illumina HiSeq 27 9 13 0 ENST00000211076.3:c.65C>G p.Pro22Arg p.P22R ENST00000211076 NM_012217.2 22 cCg/cGg 0 +ZNF595 UCSF GRCh37 4 85996 85997 + non_coding_transcript_exon_variant RNA INS - - A NOVEL P16_Pri Untested WXS Illumina HiSeq 6 0 ENST00000380882.5:n.377dup *126* ENST00000380882 0 +ABR UCSF GRCh37 17 953786 953786 + synonymous_variant Silent SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 28 11 61 0 ENST00000302538.5:c.1650G>A p.Lys550= p.K550= ENST00000302538 NM_021962.3 550 aaG/aaA 0 +ANKRD30B UCSF GRCh37 18 14852419 14852419 + missense_variant Missense_Mutation SNP A A T NOVEL P16_Rec Untested WXS Illumina HiSeq 44 22 102 0 ENST00000358984.4:c.4119A>T p.Glu1373Asp p.E1373D ENST00000358984 NM_001145029.1 1373 gaA/gaT 0 +ATRX UCSF GRCh37 X 76939906 76939907 + frameshift_variant Frame_Shift_Ins INS - - TTACATGCAGTGACCAAGTCCAACAAAGGCTCTGGGTGACAAATGTAGC NOVEL P16_Rec Untested WXS Illumina HiSeq 6 0 ENST00000373344.5:c.841_842insGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAA p.Asn281SerfsTer21 p.N281Sfs*21 ENST00000373344 NM_000489.3 281 aac/aGCTACATTTGTCACCCAGAGCCTTTGTTGGACTTGGTCACTGCATGTAAac 0 +C10orf12 UCSF GRCh37 10 98744566 98744566 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 58 29 165 0 ENST00000286067.2:c.3419C>T p.Thr1140Met p.T1140M ENST00000286067 NM_015652.2 1140 aCg/aTg 0 +CALN1 UCSF GRCh37 7 71252852 71252852 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 29 19 80 0 ENST00000395275.2:c.694C>T p.Arg232Trp p.R232W ENST00000395275 NM_031468.3 232 Cgg/Tgg 0 +COL6A3 UCSF GRCh37 2 238289831 238289831 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 76 12 138 0 ENST00000295550.4:c.1624G>A p.Gly542Ser p.G542S ENST00000295550 NM_004369.3 542 Ggc/Agc 0 +CRIPAK UCSF GRCh37 4 1388817 1388817 + missense_variant Missense_Mutation SNP C C G 1000g2011may_all_0.1284 P16_Rec Untested WXS Illumina HiSeq 58 16 25 1 ENST00000324803.4:c.518C>G p.Pro173Arg p.P173R ENST00000324803 NM_175918.3 173 cCa/cGa 0 +CRIPAK UCSF GRCh37 4 1388819 1388819 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 58 16 29 1 ENST00000324803.4:c.520T>C p.Cys174Arg p.C174R ENST00000324803 NM_175918.3 174 Tgt/Cgt 0 +CTPS2 UCSF GRCh37 X 16627738 16627738 + synonymous_variant Silent SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 45 31 100 0 ENST00000443824.1:c.1617G>A p.Pro539= p.P539= ENST00000443824 NM_001144002.1 539 ccG/ccA 0 +CYP2D6 UCSF GRCh37 22 42524214 42524215 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P16_Rec Untested WXS Illumina HiSeq 9 0 ENST00000360608.5:c.805dup p.Arg269ProfsTer5 p.R269Pfs*5 ENST00000360608 NM_000106.5 268 -/C 0 +DIP2A UCSF GRCh37 21 47924280 47924280 + missense_variant Missense_Mutation SNP A A C NOVEL P16_Rec Untested WXS Illumina HiSeq 84 62 203 0 ENST00000417564.2:c.662A>C p.His221Pro p.H221P ENST00000417564 221 cAt/cCt 0 +DMD UCSF GRCh37 X 31792227 31792227 + synonymous_variant Silent SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 75 15 128 0 ENST00000357033.4:c.7392C>T p.Ser2464= p.S2464= ENST00000357033 NM_004007.2 2464 tcC/tcT 0 +DUX2 UCSF GRCh37 4 190989668 190989668 + non_coding_transcript_exon_variant RNA SNP C C G 1000g2010nov_all_0.054 P16_Rec Untested WXS Illumina HiSeq 63 8 40 1 ENST00000536428.1:n.873C>G *291* ENST00000536428 0 +EPB41L4B UCSF GRCh37 9 111979226 111979226 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 60 41 129 0 ENST00000374566.3:c.1609A>G p.Asn537Asp p.N537D ENST00000374566 NM_019114.3 537 Aac/Gac 0 +EPPK1 UCSF GRCh37 8 144940543 144940543 + synonymous_variant Silent SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 46 7 10 0 ENST00000525985.1:c.6879C>T p.Gly2293= p.G2293= ENST00000525985 NM_031308.2 2293 ggC/ggT 0 +FSCB UCSF GRCh37 14 44974261 44974261 + missense_variant Missense_Mutation SNP C C A NOVEL P16_Rec Untested WXS Illumina HiSeq 14 4 51 1 ENST00000340446.4:c.1930G>T p.Ala644Ser p.A644S ENST00000340446 NM_032135.3 644 Gct/Tct 0 +GBP4 UCSF GRCh37 1 89651065 89651065 + missense_variant Missense_Mutation SNP T T A NOVEL P16_Rec Untested WXS Illumina HiSeq 96 37 176 0 ENST00000355754.6:c.1795A>T p.Ser599Cys p.S599C ENST00000355754 NM_052941.4 599 Agc/Tgc 0 +HIRIP3 UCSF GRCh37 16 30006689 30006689 + missense_variant Missense_Mutation SNP A A C NOVEL P16_Rec Untested WXS Illumina HiSeq 21 6 25 2 ENST00000279392.3:c.161T>G p.Val54Gly p.V54G ENST00000279392 NM_003609.4 54 gTg/gGg 0 +HLA-B UCSF GRCh37 6 31324104 31324104 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.092,1000g2011may_all_0.1271,snp132_rs17839985 P16_Rec Untested WXS Illumina HiSeq 18 5 26 1 ENST00000412585.2:c.459C>T p.Asp153= p.D153= ENST00000412585 NM_005514.6 153 gaC/gaT 0 +HLA-C UCSF GRCh37 6 31239602 31239602 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.030,1000g2011may_all_0.1058,snp132_rs1050441 P16_Rec Untested WXS Illumina HiSeq 8 7 9 0 ENST00000376228.5:c.117C>T p.Pro39= p.P39= ENST00000376228 NM_002117.5 39 ccC/ccT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 52 29 148 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LARP7 UCSF GRCh37 4 113575231 113575231 + synonymous_variant Silent SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 65 41 114 0 ENST00000509061.1:c.1605C>T p.His535= p.H535= ENST00000509061 NM_001267039.1 535 caC/caT 0 +LRCH4 UCSF GRCh37 7 100179740 100179740 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 20 18 48 0 ENST00000310300.6:c.416G>A p.Arg139Lys p.R139K ENST00000310300 NM_002319.3 139 aGg/aAg 0 +MATN3 UCSF GRCh37 2 20205936 20205936 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 64 48 153 0 ENST00000407540.3:c.359C>T p.Thr120Met p.T120M ENST00000407540 NM_002381.4 120 aCg/aTg 0 +MGAT5 UCSF GRCh37 2 135185961 135185961 + missense_variant Missense_Mutation SNP T T G NOVEL P16_Rec Untested WXS Illumina HiSeq 49 23 120 0 ENST00000409645.1:c.1820T>G p.Phe607Cys p.F607C ENST00000409645 607 tTt/tGt 0 +MS4A6A UCSF GRCh37 11 59949075 59949075 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0028,snp132_rs113133013 P16_Rec Untested WXS Illumina HiSeq 81 46 151 0 ENST00000412309.2:c.210C>T p.His70= p.H70= ENST00000412309 NM_022349.3 70 caC/caT 0 +MYCBP2 UCSF GRCh37 13 77844582 77844582 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 37 41 140 0 ENST00000544440.2:c.923A>G p.Lys308Arg p.K308R ENST00000544440 308 aAg/aGg 0 +NAV3 UCSF GRCh37 12 78513514 78513514 + missense_variant Missense_Mutation SNP G G C NOVEL P16_Rec Untested WXS Illumina HiSeq 64 31 129 0 ENST00000536525.2:c.3538G>C p.Glu1180Gln p.E1180Q ENST00000536525 NM_014903.4 1180 Gaa/Caa 0 +NBPF3 UCSF GRCh37 1 21806606 21806606 + missense_variant Missense_Mutation SNP T T G NOVEL P16_Rec Untested WXS Illumina HiSeq 68 8 138 1 ENST00000318249.5:c.1271T>G p.Phe424Cys p.F424C ENST00000318249 NM_032264.4 424 tTt/tGt 0 +ODZ1 UCSF GRCh37 X 124097540 124097540 + synonymous_variant Silent SNP T T A NOVEL P16_Rec Untested WXS Illumina HiSeq 152 18 247 0 ENST00000422452.2:c.63A>T p.Leu21= p.L21= ENST00000422452 NM_001163279.1 21 ctA/ctT 0 +PARP3 UCSF GRCh37 3 51979175 51979175 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 38 7 97 0 ENST00000398755.3:c.817G>A p.Gly273Ser p.G273S ENST00000398755 273 Ggc/Agc 0 +PGBD1 UCSF GRCh37 6 28269997 28269997 + missense_variant Missense_Mutation SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 54 42 123 0 ENST00000405948.2:c.2366C>T p.Pro789Leu p.P789L ENST00000405948 NM_001184743.1 789 cCc/cTc 0 +PLEKHG3 UCSF GRCh37 14 65208349 65208349 + missense_variant Missense_Mutation SNP A A G NOVEL P16_Rec Untested WXS Illumina HiSeq 47 16 95 0 ENST00000247226.7:c.1946A>G p.Lys649Arg p.K649R ENST00000247226 NM_015549.1 649 aAg/aGg 0 +PLXNA3 UCSF GRCh37 X 153698095 153698095 + missense_variant Missense_Mutation SNP C C A NOVEL P16_Rec Untested WXS Illumina HiSeq 25 7 61 0 ENST00000369682.3:c.4763C>A p.Ser1588Tyr p.S1588Y ENST00000369682 NM_017514.3 1588 tCc/tAc 0 +PTPRK UCSF GRCh37 6 128385918 128385918 + missense_variant Missense_Mutation SNP G G A NOVEL P16_Rec Untested WXS Illumina HiSeq 71 17 99 0 ENST00000368213.5:c.2179C>T p.Arg727Cys p.R727C ENST00000368213 NM_001135648.1 727 Cgc/Tgc 0 +SLC39A12 UCSF GRCh37 10 18292136 18292136 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 131 35 172 0 ENST00000377369.2:c.1796T>C p.Met599Thr p.M599T ENST00000377369 NM_001145195.1 599 aTg/aCg 0 +TH1L UCSF GRCh37 20 57565028 57565028 + missense_variant Missense_Mutation SNP G G C NOVEL P16_Rec Untested WXS Illumina HiSeq 17 16 63 0 ENST00000602795.1:c.827G>C p.Arg276Pro p.R276P ENST00000602795 NM_198976.2 276 cGc/cCc 0 +TP53 UCSF GRCh37 17 7578535 7578535 + missense_variant Missense_Mutation SNP T T C NOVEL P16_Rec Untested WXS Illumina HiSeq 6 25 44 0 ENST00000269305.4:c.395A>G p.Lys132Arg p.K132R ENST00000269305 NM_001126112.2 132 aAg/aGg 0 +TPSD1 UCSF GRCh37 16 1306346 1306346 + missense_variant Missense_Mutation SNP C C G snp132_rs3865205 P16_Rec Untested WXS Illumina HiSeq 19 14 13 0 ENST00000211076.3:c.65C>G p.Pro22Arg p.P22R ENST00000211076 NM_012217.2 22 cCg/cGg 0 +TSR1 UCSF GRCh37 17 2234404 2234404 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 78 30 124 0 ENST00000301364.5:c.1497-1G>A p.X499_splice ENST00000301364 NM_018128.4 0 +ZCCHC14 UCSF GRCh37 16 87451327 87451327 + synonymous_variant Silent SNP A A C NOVEL P16_Rec Untested WXS Illumina HiSeq 31 8 16 1 ENST00000268616.4:c.711T>G p.Gly237= p.G237= ENST00000268616 NM_015144.2 237 ggT/ggG 0 +ZNF560 UCSF GRCh37 19 9578900 9578900 + synonymous_variant Silent SNP C C T NOVEL P16_Rec Untested WXS Illumina HiSeq 112 16 163 0 ENST00000301480.4:c.723G>A p.Thr241= p.T241= ENST00000301480 NM_152476.2 241 acG/acA 0 +ABCA10 UCSF GRCh37 17 67170804 67170804 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Pri_A somatic WXS Sanger Illumina HiSeq 165 142 240 0 ENST00000269081.4:c.2992A>C p.Ile998Leu p.I998L ENST00000269081 NM_080282.3 998 Att/Ctt 0 +ANKRD33 UCSF GRCh37 12 52283232 52283232 + synonymous_variant Silent SNP C C A NOVEL P17_Pri_A Untested WXS Illumina HiSeq 66 59 119 1 ENST00000301190.6:c.603C>A p.Leu201= p.L201= ENST00000301190 NM_001130015.1 201 ctC/ctA 0 +ATRX UCSF GRCh37 X 76937641 76937645 + frameshift_variant Frame_Shift_Del DEL TTAAT TTAAT - NOVEL P17_Pri_A Untested WXS Illumina HiSeq 105 0 ENST00000373344.5:c.3103_3107del p.Ile1035GlufsTer5 p.I1035Efs*5 ENST00000373344 NM_000489.3 1035 ATTAAg/g 0 +C7orf10 UCSF GRCh37 7 40221586 40221586 + stop_gained Nonsense_Mutation SNP T T G NOVEL P17_Pri_A Untested WXS Illumina HiSeq 67 46 93 0 ENST00000309930.5:c.206T>G p.Leu69Ter p.L69* ENST00000309930 NM_024728.2 69 tTa/tGa 0 +CD24 UCSF GRCh37 Y 21154569 21154569 + non_coding_transcript_exon_variant RNA SNP A A G snp132_rs17855271 P17_Pri_A Untested WXS Illumina HiSeq 20 4 22 1 ENST00000382840.3:n.27T>C *9* ENST00000382840 0 +CD3EAP UCSF GRCh37 19 45911872 45911873 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P17_Pri_A Untested WXS Illumina HiSeq 18 0 ENST00000309424.3:c.653dup p.Asn218LysfsTer58 p.N218Kfs*58 ENST00000309424 NM_012099.1 216 aaa/aAaa 0 +CECR5 UCSF GRCh37 22 17619009 17619009 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Pri_A Untested WXS Illumina HiSeq 78 31 82 0 ENST00000336737.4:c.1174T>C p.Cys392Arg p.C392R ENST00000336737 NM_033070.2 392 Tgc/Cgc 0 +GPR128 UCSF GRCh37 3 100349558 100349558 + missense_variant Missense_Mutation SNP G G C NOVEL P17_Pri_A Untested WXS Illumina HiSeq 68 41 83 0 ENST00000273352.3:c.239G>C p.Cys80Ser p.C80S ENST00000273352 NM_032787.2 80 tGt/tCt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_A Untested WXS Illumina HiSeq 90 69 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LRRC16B UCSF GRCh37 14 24531921 24531921 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_A Untested WXS Illumina HiSeq 46 39 72 0 ENST00000342740.5:c.2572C>T p.Arg858Trp p.R858W ENST00000342740 NM_138360.3 858 Cgg/Tgg 0 +MED20 UCSF GRCh37 6 41875026 41875026 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P17_Pri_A somatic WXS Sanger Illumina HiSeq 59 15 47 0 ENST00000265350.4:c.424-1G>A p.X142_splice ENST00000265350 NM_004275.3 0 +NOTCH4 UCSF GRCh37 6 32170335 32170335 + missense_variant Missense_Mutation SNP G G C NOVEL P17_Pri_A Untested WXS Illumina HiSeq 22 3 33 0 ENST00000375023.3:c.3273C>G p.Cys1091Trp p.C1091W ENST00000375023 NM_004557.3 1091 tgC/tgG 0 +RFX7 UCSF GRCh37 15 56385946 56385946 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Pri_A Untested WXS Illumina HiSeq 171 140 322 0 ENST00000423270.1:c.3980A>G p.Asn1327Ser p.N1327S ENST00000423270 NM_022841.5 1327 aAt/aGt 0 +SLC4A3 UCSF GRCh37 2 220497665 220497665 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Pri_A Untested WXS Illumina HiSeq 49 10 64 0 ENST00000373762.3:c.1292T>C p.Ile431Thr p.I431T ENST00000373762 NM_005070.3 431 aTt/aCt 0 +SOX8 UCSF GRCh37 16 1035205 1035205 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Pri_A somatic WXS Sanger Illumina HiSeq 30 5 28 0 ENST00000293894.3:c.1160A>G p.Gln387Arg p.Q387R ENST00000293894 NM_014587.3 387 cAg/cGg 0 +TMEM131 UCSF GRCh37 2 98388775 98388775 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Pri_A Untested WXS Illumina HiSeq 215 174 334 0 ENST00000186436.5:c.4433C>A p.Thr1478Lys p.T1478K ENST00000186436 NM_015348.1 1478 aCa/aAa 0 +TP53 UCSF GRCh37 17 7578403 7578403 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Pri_A somatic WXS Sanger Illumina HiSeq 17 111 73 0 ENST00000269305.4:c.527G>T p.Cys176Phe p.C176F ENST00000269305 NM_001126112.2 176 tGc/tTc 0 +ZNF628 UCSF GRCh37 19 55993060 55993060 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Pri_A Untested WXS Illumina HiSeq 49 45 63 0 ENST00000598519.1:c.500G>A p.Arg167His p.R167H ENST00000598519 NM_033113.2 167 cGc/cAc 0 +ABCA10 UCSF GRCh37 17 67170804 67170804 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Pri_B somatic WXS Sanger Illumina HiSeq 172 122 240 0 ENST00000269081.4:c.2992A>C p.Ile998Leu p.I998L ENST00000269081 NM_080282.3 998 Att/Ctt 0 +ANKRD33 UCSF GRCh37 12 52283232 52283232 + synonymous_variant Silent SNP C C A NOVEL P17_Pri_B Untested WXS Illumina HiSeq 77 57 119 1 ENST00000301190.6:c.603C>A p.Leu201= p.L201= ENST00000301190 NM_001130015.1 201 ctC/ctA 0 +ATRX UCSF GRCh37 X 76937641 76937645 + frameshift_variant Frame_Shift_Del DEL TTAAT TTAAT - NOVEL P17_Pri_B Untested WXS Illumina HiSeq 107 0 ENST00000373344.5:c.3103_3107del p.Ile1035GlufsTer5 p.I1035Efs*5 ENST00000373344 NM_000489.3 1035 ATTAAg/g 0 +C7orf10 UCSF GRCh37 7 40221586 40221586 + stop_gained Nonsense_Mutation SNP T T G NOVEL P17_Pri_B Untested WXS Illumina HiSeq 54 36 93 0 ENST00000309930.5:c.206T>G p.Leu69Ter p.L69* ENST00000309930 NM_024728.2 69 tTa/tGa 0 +CD3EAP UCSF GRCh37 19 45911872 45911873 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P17_Pri_B Untested WXS Illumina HiSeq 39 0 ENST00000309424.3:c.653dup p.Asn218LysfsTer58 p.N218Kfs*58 ENST00000309424 NM_012099.1 216 aaa/aAaa 0 +CECR5 UCSF GRCh37 22 17619009 17619009 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Pri_B Untested WXS Illumina HiSeq 44 35 82 0 ENST00000336737.4:c.1174T>C p.Cys392Arg p.C392R ENST00000336737 NM_033070.2 392 Tgc/Cgc 0 +GPR128 UCSF GRCh37 3 100349558 100349558 + missense_variant Missense_Mutation SNP G G C NOVEL P17_Pri_B Untested WXS Illumina HiSeq 47 44 83 0 ENST00000273352.3:c.239G>C p.Cys80Ser p.C80S ENST00000273352 NM_032787.2 80 tGt/tCt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_B Untested WXS Illumina HiSeq 52 50 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LRRC16B UCSF GRCh37 14 24531921 24531921 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_B Untested WXS Illumina HiSeq 41 47 72 0 ENST00000342740.5:c.2572C>T p.Arg858Trp p.R858W ENST00000342740 NM_138360.3 858 Cgg/Tgg 0 +RFX7 UCSF GRCh37 15 56385946 56385946 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Pri_B Untested WXS Illumina HiSeq 251 208 322 0 ENST00000423270.1:c.3980A>G p.Asn1327Ser p.N1327S ENST00000423270 NM_022841.5 1327 aAt/aGt 0 +TMEM131 UCSF GRCh37 2 98388775 98388775 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Pri_B Untested WXS Illumina HiSeq 265 193 334 0 ENST00000186436.5:c.4433C>A p.Thr1478Lys p.T1478K ENST00000186436 NM_015348.1 1478 aCa/aAa 0 +TP53 UCSF GRCh37 17 7578403 7578403 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Pri_B somatic WXS Sanger Illumina HiSeq 17 101 73 0 ENST00000269305.4:c.527G>T p.Cys176Phe p.C176F ENST00000269305 NM_001126112.2 176 tGc/tTc 0 +ZNF628 UCSF GRCh37 19 55993060 55993060 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Pri_B Untested WXS Illumina HiSeq 48 33 63 0 ENST00000598519.1:c.500G>A p.Arg167His p.R167H ENST00000598519 NM_033113.2 167 cGc/cAc 0 +ABCA10 UCSF GRCh37 17 67170804 67170804 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Pri_C somatic WXS Sanger Illumina HiSeq 139 115 240 0 ENST00000269081.4:c.2992A>C p.Ile998Leu p.I998L ENST00000269081 NM_080282.3 998 Att/Ctt 0 +ANKRD33 UCSF GRCh37 12 52283232 52283232 + synonymous_variant Silent SNP C C A NOVEL P17_Pri_C Untested WXS Illumina HiSeq 62 57 119 1 ENST00000301190.6:c.603C>A p.Leu201= p.L201= ENST00000301190 NM_001130015.1 201 ctC/ctA 0 +ATRX UCSF GRCh37 X 76937641 76937645 + frameshift_variant Frame_Shift_Del DEL TTAAT TTAAT - NOVEL P17_Pri_C Untested WXS Illumina HiSeq 105 0 ENST00000373344.5:c.3103_3107del p.Ile1035GlufsTer5 p.I1035Efs*5 ENST00000373344 NM_000489.3 1035 ATTAAg/g 0 +C7orf10 UCSF GRCh37 7 40221586 40221586 + stop_gained Nonsense_Mutation SNP T T G NOVEL P17_Pri_C Untested WXS Illumina HiSeq 44 36 93 0 ENST00000309930.5:c.206T>G p.Leu69Ter p.L69* ENST00000309930 NM_024728.2 69 tTa/tGa 0 +CD3EAP UCSF GRCh37 19 45911872 45911873 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P17_Pri_C Untested WXS Illumina HiSeq 24 0 ENST00000309424.3:c.653dup p.Asn218LysfsTer58 p.N218Kfs*58 ENST00000309424 NM_012099.1 216 aaa/aAaa 0 +CECR5 UCSF GRCh37 22 17619009 17619009 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Pri_C Untested WXS Illumina HiSeq 48 35 82 0 ENST00000336737.4:c.1174T>C p.Cys392Arg p.C392R ENST00000336737 NM_033070.2 392 Tgc/Cgc 0 +GPR128 UCSF GRCh37 3 100349558 100349558 + missense_variant Missense_Mutation SNP G G C NOVEL P17_Pri_C Untested WXS Illumina HiSeq 42 26 83 0 ENST00000273352.3:c.239G>C p.Cys80Ser p.C80S ENST00000273352 NM_032787.2 80 tGt/tCt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_C Untested WXS Illumina HiSeq 67 48 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LRRC16B UCSF GRCh37 14 24531921 24531921 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Pri_C Untested WXS Illumina HiSeq 57 45 72 0 ENST00000342740.5:c.2572C>T p.Arg858Trp p.R858W ENST00000342740 NM_138360.3 858 Cgg/Tgg 0 +RFX7 UCSF GRCh37 15 56385946 56385946 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Pri_C Untested WXS Illumina HiSeq 224 175 322 0 ENST00000423270.1:c.3980A>G p.Asn1327Ser p.N1327S ENST00000423270 NM_022841.5 1327 aAt/aGt 0 +TMEM131 UCSF GRCh37 2 98388775 98388775 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Pri_C Untested WXS Illumina HiSeq 276 159 334 0 ENST00000186436.5:c.4433C>A p.Thr1478Lys p.T1478K ENST00000186436 NM_015348.1 1478 aCa/aAa 0 +TP53 UCSF GRCh37 17 7578403 7578403 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Pri_C somatic WXS Sanger Illumina HiSeq 9 105 73 0 ENST00000269305.4:c.527G>T p.Cys176Phe p.C176F ENST00000269305 NM_001126112.2 176 tGc/tTc 0 +ZNF628 UCSF GRCh37 19 55993060 55993060 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Pri_C Untested WXS Illumina HiSeq 48 49 63 0 ENST00000598519.1:c.500G>A p.Arg167His p.R167H ENST00000598519 NM_033113.2 167 cGc/cAc 0 +ABCC9 UCSF GRCh37 12 21954093 21954093 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 133 43 151 0 ENST00000261200.4:c.4535C>T p.Thr1512Met p.T1512M ENST00000261200 NM_020297.2 1512 aCg/aTg 0 +ADAMTSL1 UCSF GRCh37 9 18795416 18795416 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 83 0 ENST00000380548.4:c.3700del p.Ser1234ProfsTer34 p.S1234Pfs*34 ENST00000380548 NM_001040272.5 1233 gaT/ga 0 +APLF UCSF GRCh37 2 68765111 68765111 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 149 22 118 0 ENST00000303795.4:c.912T>C p.Val304= p.V304= ENST00000303795 NM_173545.2 304 gtT/gtC 0 +ARNT UCSF GRCh37 1 150795783 150795783 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 222 46 187 0 ENST00000358595.5:c.1281C>A p.Phe427Leu p.F427L ENST00000358595 NM_178427.2 427 ttC/ttA 0 +ATP2B4 UCSF GRCh37 1 203677182 203677182 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 156 119 224 0 ENST00000357681.5:c.1507C>T p.Leu503Phe p.L503F ENST00000357681 NM_001684.4 503 Ctc/Ttc 0 +ATRX UCSF GRCh37 X 76952141 76952148 + frameshift_variant Frame_Shift_Del DEL CAAAGGTT CAAAGGTT - NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 117 0 ENST00000373344.5:c.287_294del p.Lys96ArgfsTer2 p.K96Rfs*2 ENST00000373344 NM_000489.3 96 aAACCTTTG/a 0 +BCL11B UCSF GRCh37 14 99641792 99641792 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 38 9 34 0 ENST00000357195.3:c.1381G>A p.Asp461Asn p.D461N ENST00000357195 NM_138576.2 461 Gac/Aac 0 +BRD4 UCSF GRCh37 19 15354224 15354224 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 6 11 9 0 ENST00000263377.2:c.2656C>T p.Arg886Trp p.R886W ENST00000263377 NM_058243.2 886 Cgg/Tgg 0 +C19orf2 UCSF GRCh37 19 30503247 30503247 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 229 40 210 1 ENST00000542441.2:c.1234T>C p.Ser412Pro p.S412P ENST00000542441 412 Tct/Cct 0 +CARD6 UCSF GRCh37 5 40852331 40852331 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 120 47 138 0 ENST00000254691.5:c.897A>G p.Arg299= p.R299= ENST00000254691 NM_032587.3 299 agA/agG 0 +CDHR3 UCSF GRCh37 7 105662691 105662691 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014 P17_Rec1_A Untested WXS Illumina HiSeq 317 63 338 0 ENST00000317716.9:c.1873G>A p.Val625Ile p.V625I ENST00000317716 NM_152750.4 625 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89943710 89943710 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 126 53 76 0 ENST00000320585.6:c.486T>G p.Cys162Trp p.C162W ENST00000320585 NM_012124.2 162 tgT/tgG 0 +CLTC UCSF GRCh37 17 57758404 57758404 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 229 41 208 0 ENST00000269122.3:c.3051A>G p.Val1017= p.V1017= ENST00000269122 NM_004859.3 1017 gtA/gtG 0 +CRTAP UCSF GRCh37 3 33183903 33183903 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 76 33 128 0 ENST00000320954.6:c.1169A>G p.Tyr390Cys p.Y390C ENST00000320954 NM_006371.4 390 tAt/tGt 0 +CUL4A UCSF GRCh37 13 113889388 113889388 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 130 24 111 0 ENST00000375440.4:c.777T>C p.Tyr259= p.Y259= ENST00000375440 NM_001008895.2 259 taT/taC 0 +DIDO1 UCSF GRCh37 20 61513252 61513252 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 120 98 187 0 ENST00000266070.4:c.4056C>T p.Asp1352= p.D1352= ENST00000266070 NM_033081.2 1352 gaC/gaT 0 +FAT1 UCSF GRCh37 4 187518024 187518024 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P17_Rec1_A somatic WXS Sanger Illumina HiSeq 236 65 285 0 ENST00000441802.2:c.12670G>A p.Ala4224Thr p.A4224T ENST00000441802 NM_005245.3 4224 Gct/Act 0 +FRG1 UCSF GRCh37 4 190878556 190878557 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 8 0 ENST00000226798.4:c.439dup p.Met147AsnfsTer8 p.M147Nfs*8 ENST00000226798 NM_004477.2 146 aaa/aAaa 0 +FRG1 UCSF GRCh37 4 190878542 190878571 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS GTTTCACTTAGGGGAAAATGGCTTTGTTGG GTTTCACTTAGGGGAAAATGGCTTTGTTGG TGTTTCACTTAGGGGAAAATGGCTTTGTCGA NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 6 0 ENST00000226798.4:c.433-11_451delinsTGTTTCACTTAGGGGAAAATGGCTTTGTCGA p.X145_splice ENST00000226798 NM_004477.2 0 +GPR142 UCSF GRCh37 17 72363835 72363835 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 96 13 99 0 ENST00000335666.4:c.191G>T p.Gly64Val p.G64V ENST00000335666 NM_181790.1 64 gGa/gTa 0 +HEPH UCSF GRCh37 X 65409555 65409555 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 27 102 100 0 ENST00000519389.1:c.1000C>A p.Pro334Thr p.P334T ENST00000519389 334 Cct/Act 0 +HYAL4 UCSF GRCh37 7 123517035 123517035 + synonymous_variant Silent SNP A A T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 224 48 193 0 ENST00000223026.4:c.1272A>T p.Thr424= p.T424= ENST00000223026 NM_012269.2 424 acA/acT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 99 114 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL23R UCSF GRCh37 1 67724210 67724210 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 261 60 260 0 ENST00000347310.5:c.1289T>C p.Val430Ala p.V430A ENST00000347310 NM_144701.2 430 gTt/gCt 0 +KCNK15 UCSF GRCh37 20 43379023 43379023 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 70 8 60 0 ENST00000372861.3:c.537G>A p.Ser179= p.S179= ENST00000372861 NM_022358.3 179 tcG/tcA 0 +KIAA1383 UCSF GRCh37 1 232941658 232941658 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 31 17 38 0 ENST00000418460.1:c.889T>G p.Ser297Ala p.S297A ENST00000418460 NM_019090.2 297 Tcc/Gcc 0 +MDH1B UCSF GRCh37 2 207621736 207621736 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 206 29 157 0 ENST00000374412.3:c.299C>T p.Thr100Met p.T100M ENST00000374412 NM_001039845.1 100 aCg/aTg 0 +MYO7B UCSF GRCh37 2 128331590 128331590 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 200 40 194 0 ENST00000428314.1:c.688G>A p.Ala230Thr p.A230T ENST00000428314 NM_001080527.1 230 Gcg/Acg 0 +PIK3CA UCSF GRCh37 3 178952085 178952085 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 134 31 156 0 ENST00000263967.3:c.3140A>G p.His1047Arg p.H1047R ENST00000263967 NM_006218.2 1047 cAt/cGt 0 +RAD54B UCSF GRCh37 8 95390425 95390425 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 49 37 71 0 ENST00000336148.5:c.2498G>A p.Gly833Glu p.G833E ENST00000336148 NM_012415.3 833 gGa/gAa 0 +SDAD1 UCSF GRCh37 4 76902575 76902575 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 153 34 100 0 ENST00000356260.5:c.244A>G p.Lys82Glu p.K82E ENST00000356260 NM_018115.2 82 Aaa/Gaa 0 +SHISA9 UCSF GRCh37 16 13010641 13010641 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 176 54 175 0 ENST00000424107.3:c.660C>T p.Asn220= p.N220= ENST00000424107 220 aaC/aaT 0 +SHKBP1 UCSF GRCh37 19 41096697 41096697 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 61 54 94 0 ENST00000291842.5:c.1830G>A p.Pro610= p.P610= ENST00000291842 NM_138392.3 610 ccG/ccA 0 +SLC22A25 UCSF GRCh37 11 62951251 62951251 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 270 106 193 0 ENST00000306494.6:c.869A>G p.Asn290Ser p.N290S ENST00000306494 NM_199352.3 290 aAc/aGc 0 +SPAG17 UCSF GRCh37 1 118584652 118584652 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 140 104 209 0 ENST00000336338.5:c.2828A>G p.Glu943Gly p.E943G ENST00000336338 NM_206996.2 943 gAg/gGg 0 +SPTLC1 UCSF GRCh37 9 94817753 94817753 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 140 20 115 0 ENST00000262554.2:c.714T>C p.Thr238= p.T238= ENST00000262554 NM_001281303.1 238 acT/acC 0 +TMEM63B UCSF GRCh37 6 44122598 44122598 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 56 33 66 0 ENST00000259746.9:c.2477T>C p.Ile826Thr p.I826T ENST00000259746 826 aTa/aCa 0 +TP53 UCSF GRCh37 17 7578550 7578550 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 12 48 42 0 ENST00000269305.4:c.380C>T p.Ser127Phe p.S127F ENST00000269305 NM_001126112.2 127 tCc/tTc 0 +TSHB UCSF GRCh37 1 115576706 115576706 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_A Untested WXS Illumina HiSeq 301 50 282 0 ENST00000256592.1:c.275C>A p.Ala92Asp p.A92D ENST00000256592 NM_000549.4 92 gCt/gAt 0 +ZNF211 UCSF GRCh37 19 58152143 58152143 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_A somatic WXS Sanger Illumina HiSeq 174 33 137 0 ENST00000299871.5:c.484T>C p.Phe162Leu p.F162L ENST00000299871 NM_001265597.1 162 Ttc/Ctc 0 +ABCC9 UCSF GRCh37 12 21954093 21954093 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B somatic WXS Sanger Illumina HiSeq 91 30 151 0 ENST00000261200.4:c.4535C>T p.Thr1512Met p.T1512M ENST00000261200 NM_020297.2 1512 aCg/aTg 0 +ADAMTS3 UCSF GRCh37 4 73149155 73149155 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 189 54 182 0 ENST00000286657.4:c.3316A>G p.Ile1106Val p.I1106V ENST00000286657 NM_014243.2 1106 Atc/Gtc 0 +ADAMTSL1 UCSF GRCh37 9 18795416 18795416 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 67 0 ENST00000380548.4:c.3700del p.Ser1234ProfsTer34 p.S1234Pfs*34 ENST00000380548 NM_001040272.5 1233 gaT/ga 0 +ASCC2 UCSF GRCh37 22 30198032 30198032 + stop_gained Nonsense_Mutation SNP C C A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 43 7 38 0 ENST00000397771.2:c.1519G>T p.Glu507Ter p.E507* ENST00000397771 507 Gag/Tag 0 +ATP2B4 UCSF GRCh37 1 203677182 203677182 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 186 118 224 0 ENST00000357681.5:c.1507C>T p.Leu503Phe p.L503F ENST00000357681 NM_001684.4 503 Ctc/Ttc 0 +ATRX UCSF GRCh37 X 76952141 76952148 + frameshift_variant Frame_Shift_Del DEL CAAAGGTT CAAAGGTT - NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 70 0 ENST00000373344.5:c.287_294del p.Lys96ArgfsTer2 p.K96Rfs*2 ENST00000373344 NM_000489.3 96 aAACCTTTG/a 0 +AXL UCSF GRCh37 19 41727930 41727930 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_B somatic WXS Sanger Illumina HiSeq 21 6 14 0 ENST00000301178.4:c.555T>C p.Gly185= p.G185= ENST00000301178 NM_021913.4 185 ggT/ggC 0 +BCL11B UCSF GRCh37 14 99641792 99641792 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 44 10 34 0 ENST00000357195.3:c.1381G>A p.Asp461Asn p.D461N ENST00000357195 NM_138576.2 461 Gac/Aac 0 +BRD4 UCSF GRCh37 19 15354224 15354224 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 11 10 9 0 ENST00000263377.2:c.2656C>T p.Arg886Trp p.R886W ENST00000263377 NM_058243.2 886 Cgg/Tgg 0 +BRIP1 UCSF GRCh37 17 59876511 59876511 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 105 19 162 1 ENST00000259008.2:c.1290A>G p.Ile430Met p.I430M ENST00000259008 NM_032043.2 430 atA/atG 0 +CARD6 UCSF GRCh37 5 40852331 40852331 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 72 18 138 0 ENST00000254691.5:c.897A>G p.Arg299= p.R299= ENST00000254691 NM_032587.3 299 agA/agG 0 +CDHR3 UCSF GRCh37 7 105662691 105662691 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014 P17_Rec1_B Untested WXS Illumina HiSeq 404 119 338 0 ENST00000317716.9:c.1873G>A p.Val625Ile p.V625I ENST00000317716 NM_152750.4 625 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89943710 89943710 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 46 22 76 0 ENST00000320585.6:c.486T>G p.Cys162Trp p.C162W ENST00000320585 NM_012124.2 162 tgT/tgG 0 +CRTAP UCSF GRCh37 3 33183903 33183903 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 42 20 128 0 ENST00000320954.6:c.1169A>G p.Tyr390Cys p.Y390C ENST00000320954 NM_006371.4 390 tAt/tGt 0 +DIDO1 UCSF GRCh37 20 61513252 61513252 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 123 96 187 0 ENST00000266070.4:c.4056C>T p.Asp1352= p.D1352= ENST00000266070 NM_033081.2 1352 gaC/gaT 0 +DNM1L UCSF GRCh37 12 32861097 32861097 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 48 14 78 0 ENST00000549701.1:c.308A>G p.Asp103Gly p.D103G ENST00000549701 103 gAt/gGt 0 +ECI2 UCSF GRCh37 6 4133876 4133876 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 183 35 201 0 ENST00000380118.3:c.120G>A p.Gln40= p.Q40= ENST00000380118 40 caG/caA 0 +FANCA UCSF GRCh37 16 89862354 89862354 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 77 25 118 0 ENST00000389301.3:c.966T>C p.His322= p.H322= ENST00000389301 NM_000135.2 322 caT/caC 0 +FAT1 UCSF GRCh37 4 187518024 187518024 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P17_Rec1_B somatic WXS Sanger Illumina HiSeq 295 72 285 0 ENST00000441802.2:c.12670G>A p.Ala4224Thr p.A4224T ENST00000441802 NM_005245.3 4224 Gct/Act 0 +FAT1 UCSF GRCh37 4 187531037 187531037 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 242 53 246 0 ENST00000441802.2:c.9986A>G p.Asn3329Ser p.N3329S ENST00000441802 NM_005245.3 3329 aAc/aGc 0 +FLAD1 UCSF GRCh37 1 154962825 154962825 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 142 30 120 0 ENST00000292180.3:c.1375C>A p.Gln459Lys p.Q459K ENST00000292180 NM_025207.4 459 Cag/Aag 0 +GORAB UCSF GRCh37 1 170521320 170521320 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 121 33 121 0 ENST00000367763.3:c.902T>C p.Val301Ala p.V301A ENST00000367763 NM_152281.2 301 gTa/gCa 0 +HEPH UCSF GRCh37 X 65409555 65409555 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 19 97 100 0 ENST00000519389.1:c.1000C>A p.Pro334Thr p.P334T ENST00000519389 334 Cct/Act 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 75 110 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KAT6B UCSF GRCh37 10 76790463 76790463 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 254 69 210 0 ENST00000287239.4:c.5881A>G p.Met1961Val p.M1961V ENST00000287239 NM_001256468.1 1961 Atg/Gtg 0 +KIAA1383 UCSF GRCh37 1 232941658 232941658 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 29 13 38 0 ENST00000418460.1:c.889T>G p.Ser297Ala p.S297A ENST00000418460 NM_019090.2 297 Tcc/Gcc 0 +MACC1 UCSF GRCh37 7 20199790 20199790 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 86 33 151 0 ENST00000400331.5:c.194A>G p.Asn65Ser p.N65S ENST00000400331 NM_182762.3 65 aAt/aGt 0 +MBD6 UCSF GRCh37 12 57921732 57921732 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 7 0 ENST00000355673.3:c.2345delG p.Gly782GlufsTer13 p.G782Efs*13 ENST00000355673 NM_052897.3 780 Ggg/gg 0 +MYO7B UCSF GRCh37 2 128331590 128331590 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 178 61 194 0 ENST00000428314.1:c.688G>A p.Ala230Thr p.A230T ENST00000428314 NM_001080527.1 230 Gcg/Acg 0 +PIK3CA UCSF GRCh37 3 178952085 178952085 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B somatic WXS Sanger Illumina HiSeq 77 42 156 0 ENST00000263967.3:c.3140A>G p.His1047Arg p.H1047R ENST00000263967 NM_006218.2 1047 cAt/cGt 0 +PRKCH UCSF GRCh37 14 61788905 61788905 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 50 15 27 1 ENST00000332981.5:c.86T>C p.Leu29Pro p.L29P ENST00000332981 NM_006255.3 29 cTg/cCg 0 +RAD54B UCSF GRCh37 8 95390425 95390425 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 34 27 71 0 ENST00000336148.5:c.2498G>A p.Gly833Glu p.G833E ENST00000336148 NM_012415.3 833 gGa/gAa 0 +RGPD2 UCSF GRCh37 2 88125234 88125234 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 36 4 23 1 ENST00000398146.3:c.15A>G p.Lys5= p.K5= ENST00000398146 5 aaA/aaG 0 +SHISA9 UCSF GRCh37 16 13010641 13010641 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 136 38 175 0 ENST00000424107.3:c.660C>T p.Asn220= p.N220= ENST00000424107 220 aaC/aaT 0 +SHKBP1 UCSF GRCh37 19 41096697 41096697 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 67 52 94 0 ENST00000291842.5:c.1830G>A p.Pro610= p.P610= ENST00000291842 NM_138392.3 610 ccG/ccA 0 +SLC22A25 UCSF GRCh37 11 62951251 62951251 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 216 102 193 0 ENST00000306494.6:c.869A>G p.Asn290Ser p.N290S ENST00000306494 NM_199352.3 290 aAc/aGc 0 +SORCS2 UCSF GRCh37 4 7691261 7691261 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 75 31 75 0 ENST00000507866.2:c.1537G>A p.Val513Ile p.V513I ENST00000507866 NM_020777.2 513 Gta/Ata 0 +SOX6 UCSF GRCh37 11 16068204 16068204 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_B somatic WXS Sanger Illumina HiSeq 63 26 100 0 ENST00000396356.3:c.1479G>A p.Gln493= p.Q493= ENST00000396356 NM_033326.3 493 caG/caA 0 +SP6 UCSF GRCh37 17 45924768 45924768 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 22 8 22 0 ENST00000536300.1:c.1028C>T p.Ala343Val p.A343V ENST00000536300 NM_001258248.1 343 gCg/gTg 0 +SPAG17 UCSF GRCh37 1 118584652 118584652 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 140 100 209 0 ENST00000336338.5:c.2828A>G p.Glu943Gly p.E943G ENST00000336338 NM_206996.2 943 gAg/gGg 0 +TLN2 UCSF GRCh37 15 63047743 63047743 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 75 30 58 0 ENST00000561311.1:c.4489G>A p.Ala1497Thr p.A1497T ENST00000561311 1497 Gcc/Acc 0 +TMEM40 UCSF GRCh37 3 12779654 12779654 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 16 7 47 0 ENST00000314124.7:c.405A>G p.Arg135= p.R135= ENST00000314124 NM_018306.2 135 agA/agG 0 +TMEM63B UCSF GRCh37 6 44122598 44122598 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 37 32 66 0 ENST00000259746.9:c.2477T>C p.Ile826Thr p.I826T ENST00000259746 826 aTa/aCa 0 +TMPRSS11B UCSF GRCh37 4 69095151 69095151 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 123 32 173 0 ENST00000332644.5:c.770T>G p.Ile257Ser p.I257S ENST00000332644 NM_182502.3 257 aTt/aGt 0 +TP53 UCSF GRCh37 17 7578550 7578550 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 3 46 42 0 ENST00000269305.4:c.380C>T p.Ser127Phe p.S127F ENST00000269305 NM_001126112.2 127 tCc/tTc 0 +TTN UCSF GRCh37 2 179641275 179641275 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 136 41 205 0 ENST00000589042.1:c.5316T>C p.Ser1772= p.S1772= ENST00000589042 NM_001267550.1 1772 agT/agC 0 +UGT3A1 UCSF GRCh37 5 35965819 35965819 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 120 35 145 0 ENST00000274278.3:c.512G>T p.Gly171Val p.G171V ENST00000274278 NM_152404.3 171 gGc/gTc 0 +WFDC12 UCSF GRCh37 20 43752784 43752784 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_B Untested WXS Illumina HiSeq 76 17 78 0 ENST00000372785.3:c.202T>C p.Phe68Leu p.F68L ENST00000372785 NM_080869.1 68 Ttc/Ctc 0 +ABCC9 UCSF GRCh37 12 21954093 21954093 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 97 32 151 0 ENST00000261200.4:c.4535C>T p.Thr1512Met p.T1512M ENST00000261200 NM_020297.2 1512 aCg/aTg 0 +ADAMTSL1 UCSF GRCh37 9 18795416 18795416 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 55 0 ENST00000380548.4:c.3700del p.Ser1234ProfsTer34 p.S1234Pfs*34 ENST00000380548 NM_001040272.5 1233 gaT/ga 0 +ARNT UCSF GRCh37 1 150795783 150795783 + missense_variant Missense_Mutation SNP G G T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 108 15 187 0 ENST00000358595.5:c.1281C>A p.Phe427Leu p.F427L ENST00000358595 NM_178427.2 427 ttC/ttA 0 +ATP2B4 UCSF GRCh37 1 203677182 203677182 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 165 86 224 0 ENST00000357681.5:c.1507C>T p.Leu503Phe p.L503F ENST00000357681 NM_001684.4 503 Ctc/Ttc 0 +ATRX UCSF GRCh37 X 76952141 76952148 + frameshift_variant Frame_Shift_Del DEL CAAAGGTT CAAAGGTT - NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 74 0 ENST00000373344.5:c.287_294del p.Lys96ArgfsTer2 p.K96Rfs*2 ENST00000373344 NM_000489.3 96 aAACCTTTG/a 0 +BCL11B UCSF GRCh37 14 99641792 99641792 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 25 12 34 0 ENST00000357195.3:c.1381G>A p.Asp461Asn p.D461N ENST00000357195 NM_138576.2 461 Gac/Aac 0 +BRD4 UCSF GRCh37 19 15354224 15354224 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 9 7 9 0 ENST00000263377.2:c.2656C>T p.Arg886Trp p.R886W ENST00000263377 NM_058243.2 886 Cgg/Tgg 0 +C19orf2 UCSF GRCh37 19 30503247 30503247 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 152 24 210 1 ENST00000542441.2:c.1234T>C p.Ser412Pro p.S412P ENST00000542441 412 Tct/Cct 0 +CARD6 UCSF GRCh37 5 40852331 40852331 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 69 18 138 0 ENST00000254691.5:c.897A>G p.Arg299= p.R299= ENST00000254691 NM_032587.3 299 agA/agG 0 +CDHR3 UCSF GRCh37 7 105662691 105662691 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014 P17_Rec1_C Untested WXS Illumina HiSeq 476 93 338 0 ENST00000317716.9:c.1873G>A p.Val625Ile p.V625I ENST00000317716 NM_152750.4 625 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89943710 89943710 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 49 18 76 0 ENST00000320585.6:c.486T>G p.Cys162Trp p.C162W ENST00000320585 NM_012124.2 162 tgT/tgG 0 +CLTC UCSF GRCh37 17 57758404 57758404 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 160 26 208 0 ENST00000269122.3:c.3051A>G p.Val1017= p.V1017= ENST00000269122 NM_004859.3 1017 gtA/gtG 0 +CRTAP UCSF GRCh37 3 33183903 33183903 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 54 14 128 0 ENST00000320954.6:c.1169A>G p.Tyr390Cys p.Y390C ENST00000320954 NM_006371.4 390 tAt/tGt 0 +DIDO1 UCSF GRCh37 20 61513252 61513252 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 152 82 187 0 ENST00000266070.4:c.4056C>T p.Asp1352= p.D1352= ENST00000266070 NM_033081.2 1352 gaC/gaT 0 +FAT1 UCSF GRCh37 4 187518024 187518024 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P17_Rec1_C somatic WXS Sanger Illumina HiSeq 291 87 285 0 ENST00000441802.2:c.12670G>A p.Ala4224Thr p.A4224T ENST00000441802 NM_005245.3 4224 Gct/Act 0 +HEPH UCSF GRCh37 X 65409555 65409555 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 23 76 100 0 ENST00000519389.1:c.1000C>A p.Pro334Thr p.P334T ENST00000519389 334 Cct/Act 0 +HYAL4 UCSF GRCh37 7 123517035 123517035 + synonymous_variant Silent SNP A A T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 182 31 193 0 ENST00000223026.4:c.1272A>T p.Thr424= p.T424= ENST00000223026 NM_012269.2 424 acA/acT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 60 77 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL23R UCSF GRCh37 1 67724210 67724210 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 173 39 260 0 ENST00000347310.5:c.1289T>C p.Val430Ala p.V430A ENST00000347310 NM_144701.2 430 gTt/gCt 0 +KCNK15 UCSF GRCh37 20 43379023 43379023 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 123 24 60 0 ENST00000372861.3:c.537G>A p.Ser179= p.S179= ENST00000372861 NM_022358.3 179 tcG/tcA 0 +KIAA1383 UCSF GRCh37 1 232941658 232941658 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 28 17 38 0 ENST00000418460.1:c.889T>G p.Ser297Ala p.S297A ENST00000418460 NM_019090.2 297 Tcc/Gcc 0 +MDH1B UCSF GRCh37 2 207621736 207621736 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 92 14 157 0 ENST00000374412.3:c.299C>T p.Thr100Met p.T100M ENST00000374412 NM_001039845.1 100 aCg/aTg 0 +MYO7B UCSF GRCh37 2 128331590 128331590 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 180 57 194 0 ENST00000428314.1:c.688G>A p.Ala230Thr p.A230T ENST00000428314 NM_001080527.1 230 Gcg/Acg 0 +PIK3CA UCSF GRCh37 3 178952085 178952085 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 88 16 156 0 ENST00000263967.3:c.3140A>G p.His1047Arg p.H1047R ENST00000263967 NM_006218.2 1047 cAt/cGt 0 +RAD54B UCSF GRCh37 8 95390425 95390425 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 40 18 71 0 ENST00000336148.5:c.2498G>A p.Gly833Glu p.G833E ENST00000336148 NM_012415.3 833 gGa/gAa 0 +SDAD1 UCSF GRCh37 4 76902575 76902575 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 72 8 100 0 ENST00000356260.5:c.244A>G p.Lys82Glu p.K82E ENST00000356260 NM_018115.2 82 Aaa/Gaa 0 +SHISA9 UCSF GRCh37 16 13010641 13010641 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 122 27 175 0 ENST00000424107.3:c.660C>T p.Asn220= p.N220= ENST00000424107 220 aaC/aaT 0 +SHKBP1 UCSF GRCh37 19 41096697 41096697 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 64 44 94 0 ENST00000291842.5:c.1830G>A p.Pro610= p.P610= ENST00000291842 NM_138392.3 610 ccG/ccA 0 +SLC22A25 UCSF GRCh37 11 62951251 62951251 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 218 90 193 0 ENST00000306494.6:c.869A>G p.Asn290Ser p.N290S ENST00000306494 NM_199352.3 290 aAc/aGc 0 +SPAG17 UCSF GRCh37 1 118584652 118584652 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 146 87 209 0 ENST00000336338.5:c.2828A>G p.Glu943Gly p.E943G ENST00000336338 NM_206996.2 943 gAg/gGg 0 +TMEM63B UCSF GRCh37 6 44122598 44122598 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 35 24 66 0 ENST00000259746.9:c.2477T>C p.Ile826Thr p.I826T ENST00000259746 826 aTa/aCa 0 +TNFSF9 UCSF GRCh37 19 6535032 6535032 + synonymous_variant Silent SNP G G T NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 25 6 32 0 ENST00000245817.3:c.720G>T p.Val240= p.V240= ENST00000245817 NM_003811.3 240 gtG/gtT 0 +TP53 UCSF GRCh37 17 7578550 7578550 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 9 38 42 0 ENST00000269305.4:c.380C>T p.Ser127Phe p.S127F ENST00000269305 NM_001126112.2 127 tCc/tTc 0 +TSHB UCSF GRCh37 1 115576706 115576706 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_C Untested WXS Illumina HiSeq 300 49 282 0 ENST00000256592.1:c.275C>A p.Ala92Asp p.A92D ENST00000256592 NM_000549.4 92 gCt/gAt 0 +ZNF211 UCSF GRCh37 19 58152143 58152143 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_C somatic WXS Sanger Illumina HiSeq 130 24 137 0 ENST00000299871.5:c.484T>C p.Phe162Leu p.F162L ENST00000299871 NM_001265597.1 162 Ttc/Ctc 0 +ABCC9 UCSF GRCh37 12 21954093 21954093 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 86 44 151 0 ENST00000261200.4:c.4535C>T p.Thr1512Met p.T1512M ENST00000261200 NM_020297.2 1512 aCg/aTg 0 +ADAMTS3 UCSF GRCh37 4 73149155 73149155 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 191 57 182 0 ENST00000286657.4:c.3316A>G p.Ile1106Val p.I1106V ENST00000286657 NM_014243.2 1106 Atc/Gtc 0 +ADAMTSL1 UCSF GRCh37 9 18795416 18795416 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 55 0 ENST00000380548.4:c.3700del p.Ser1234ProfsTer34 p.S1234Pfs*34 ENST00000380548 NM_001040272.5 1233 gaT/ga 0 +ASCC2 UCSF GRCh37 22 30198032 30198032 + stop_gained Nonsense_Mutation SNP C C A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 30 13 38 0 ENST00000397771.2:c.1519G>T p.Glu507Ter p.E507* ENST00000397771 507 Gag/Tag 0 +ATP2B4 UCSF GRCh37 1 203677182 203677182 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 150 122 224 0 ENST00000357681.5:c.1507C>T p.Leu503Phe p.L503F ENST00000357681 NM_001684.4 503 Ctc/Ttc 0 +ATRX UCSF GRCh37 X 76952141 76952148 + frameshift_variant Frame_Shift_Del DEL CAAAGGTT CAAAGGTT - NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 67 0 ENST00000373344.5:c.287_294del p.Lys96ArgfsTer2 p.K96Rfs*2 ENST00000373344 NM_000489.3 96 aAACCTTTG/a 0 +BCL11B UCSF GRCh37 14 99641792 99641792 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 40 12 34 0 ENST00000357195.3:c.1381G>A p.Asp461Asn p.D461N ENST00000357195 NM_138576.2 461 Gac/Aac 0 +BRD4 UCSF GRCh37 19 15354224 15354224 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 13 7 9 0 ENST00000263377.2:c.2656C>T p.Arg886Trp p.R886W ENST00000263377 NM_058243.2 886 Cgg/Tgg 0 +BRIP1 UCSF GRCh37 17 59876511 59876511 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 82 21 162 1 ENST00000259008.2:c.1290A>G p.Ile430Met p.I430M ENST00000259008 NM_032043.2 430 atA/atG 0 +CARD6 UCSF GRCh37 5 40852331 40852331 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 73 16 138 0 ENST00000254691.5:c.897A>G p.Arg299= p.R299= ENST00000254691 NM_032587.3 299 agA/agG 0 +CDHR3 UCSF GRCh37 7 105662691 105662691 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0014 P17_Rec1_D Untested WXS Illumina HiSeq 424 111 338 0 ENST00000317716.9:c.1873G>A p.Val625Ile p.V625I ENST00000317716 NM_152750.4 625 Gtc/Atc 0 +CHORDC1 UCSF GRCh37 11 89943710 89943710 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 46 11 76 0 ENST00000320585.6:c.486T>G p.Cys162Trp p.C162W ENST00000320585 NM_012124.2 162 tgT/tgG 0 +CRTAP UCSF GRCh37 3 33183903 33183903 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 37 17 128 0 ENST00000320954.6:c.1169A>G p.Tyr390Cys p.Y390C ENST00000320954 NM_006371.4 390 tAt/tGt 0 +DIDO1 UCSF GRCh37 20 61513252 61513252 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 102 98 187 0 ENST00000266070.4:c.4056C>T p.Asp1352= p.D1352= ENST00000266070 NM_033081.2 1352 gaC/gaT 0 +DNM1L UCSF GRCh37 12 32861097 32861097 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 39 9 78 0 ENST00000549701.1:c.308A>G p.Asp103Gly p.D103G ENST00000549701 103 gAt/gGt 0 +ECI2 UCSF GRCh37 6 4133876 4133876 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 133 29 201 0 ENST00000380118.3:c.120G>A p.Gln40= p.Q40= ENST00000380118 40 caG/caA 0 +FANCA UCSF GRCh37 16 89862354 89862354 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 77 28 118 0 ENST00000389301.3:c.966T>C p.His322= p.H322= ENST00000389301 NM_000135.2 322 caT/caC 0 +FAT1 UCSF GRCh37 4 187518024 187518024 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P17_Rec1_D somatic WXS Sanger Illumina HiSeq 269 73 285 0 ENST00000441802.2:c.12670G>A p.Ala4224Thr p.A4224T ENST00000441802 NM_005245.3 4224 Gct/Act 0 +FAT1 UCSF GRCh37 4 187531037 187531037 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 248 71 246 0 ENST00000441802.2:c.9986A>G p.Asn3329Ser p.N3329S ENST00000441802 NM_005245.3 3329 aAc/aGc 0 +FGFBP1 UCSF GRCh37 4 15937919 15937919 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 163 38 192 0 ENST00000382333.1:c.337T>C p.Trp113Arg p.W113R ENST00000382333 NM_005130.4 113 Tgg/Cgg 0 +FLAD1 UCSF GRCh37 1 154962825 154962825 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 114 31 120 0 ENST00000292180.3:c.1375C>A p.Gln459Lys p.Q459K ENST00000292180 NM_025207.4 459 Cag/Aag 0 +GORAB UCSF GRCh37 1 170521320 170521320 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 113 46 121 0 ENST00000367763.3:c.902T>C p.Val301Ala p.V301A ENST00000367763 NM_152281.2 301 gTa/gCa 0 +HEPH UCSF GRCh37 X 65409555 65409555 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 9 90 100 0 ENST00000519389.1:c.1000C>A p.Pro334Thr p.P334T ENST00000519389 334 Cct/Act 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 57 91 114 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KAT6B UCSF GRCh37 10 76790463 76790463 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 273 71 210 0 ENST00000287239.4:c.5881A>G p.Met1961Val p.M1961V ENST00000287239 NM_001256468.1 1961 Atg/Gtg 0 +KIAA1383 UCSF GRCh37 1 232941658 232941658 + missense_variant Missense_Mutation SNP T T G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 13 12 38 0 ENST00000418460.1:c.889T>G p.Ser297Ala p.S297A ENST00000418460 NM_019090.2 297 Tcc/Gcc 0 +MACC1 UCSF GRCh37 7 20199790 20199790 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 86 19 151 0 ENST00000400331.5:c.194A>G p.Asn65Ser p.N65S ENST00000400331 NM_182762.3 65 aAt/aGt 0 +MBD6 UCSF GRCh37 12 57921732 57921732 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 8 0 ENST00000355673.3:c.2345delG p.Gly782GlufsTer13 p.G782Efs*13 ENST00000355673 NM_052897.3 780 Ggg/gg 0 +MDH1B UCSF GRCh37 2 207621736 207621736 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 87 12 157 0 ENST00000374412.3:c.299C>T p.Thr100Met p.T100M ENST00000374412 NM_001039845.1 100 aCg/aTg 0 +MYO7B UCSF GRCh37 2 128331590 128331590 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 176 58 194 0 ENST00000428314.1:c.688G>A p.Ala230Thr p.A230T ENST00000428314 NM_001080527.1 230 Gcg/Acg 0 +PIK3CA UCSF GRCh37 3 178952085 178952085 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 73 28 156 0 ENST00000263967.3:c.3140A>G p.His1047Arg p.H1047R ENST00000263967 NM_006218.2 1047 cAt/cGt 0 +PLEKHG1 UCSF GRCh37 6 151151933 151151933 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 132 40 163 0 ENST00000367328.1:c.1686C>T p.Phe562= p.F562= ENST00000367328 NM_001029884.1 562 ttC/ttT 0 +PRKCH UCSF GRCh37 14 61788905 61788905 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 55 18 27 1 ENST00000332981.5:c.86T>C p.Leu29Pro p.L29P ENST00000332981 NM_006255.3 29 cTg/cCg 0 +RAD54B UCSF GRCh37 8 95390425 95390425 + missense_variant Missense_Mutation SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 36 27 71 0 ENST00000336148.5:c.2498G>A p.Gly833Glu p.G833E ENST00000336148 NM_012415.3 833 gGa/gAa 0 +RGPD2 UCSF GRCh37 2 88125234 88125234 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 46 6 23 1 ENST00000398146.3:c.15A>G p.Lys5= p.K5= ENST00000398146 5 aaA/aaG 0 +SHISA9 UCSF GRCh37 16 13010641 13010641 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 114 34 175 0 ENST00000424107.3:c.660C>T p.Asn220= p.N220= ENST00000424107 220 aaC/aaT 0 +SHKBP1 UCSF GRCh37 19 41096697 41096697 + synonymous_variant Silent SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 65 61 94 0 ENST00000291842.5:c.1830G>A p.Pro610= p.P610= ENST00000291842 NM_138392.3 610 ccG/ccA 0 +SLC22A25 UCSF GRCh37 11 62951251 62951251 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 235 94 193 0 ENST00000306494.6:c.869A>G p.Asn290Ser p.N290S ENST00000306494 NM_199352.3 290 aAc/aGc 0 +SORCS2 UCSF GRCh37 4 7691261 7691261 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 64 23 75 0 ENST00000507866.2:c.1537G>A p.Val513Ile p.V513I ENST00000507866 NM_020777.2 513 Gta/Ata 0 +SOX6 UCSF GRCh37 11 16068204 16068204 + synonymous_variant Silent SNP C C T NOVEL P17_Rec1_D somatic WXS Sanger Illumina HiSeq 84 24 100 0 ENST00000396356.3:c.1479G>A p.Gln493= p.Q493= ENST00000396356 NM_033326.3 493 caG/caA 0 +SP6 UCSF GRCh37 17 45924768 45924768 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 36 10 22 0 ENST00000536300.1:c.1028C>T p.Ala343Val p.A343V ENST00000536300 NM_001258248.1 343 gCg/gTg 0 +SPAG17 UCSF GRCh37 1 118584652 118584652 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 116 93 209 0 ENST00000336338.5:c.2828A>G p.Glu943Gly p.E943G ENST00000336338 NM_206996.2 943 gAg/gGg 0 +TLN2 UCSF GRCh37 15 63047743 63047743 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 60 15 58 0 ENST00000561311.1:c.4489G>A p.Ala1497Thr p.A1497T ENST00000561311 1497 Gcc/Acc 0 +TMEM40 UCSF GRCh37 3 12779654 12779654 + synonymous_variant Silent SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 14 7 47 0 ENST00000314124.7:c.405A>G p.Arg135= p.R135= ENST00000314124 NM_018306.2 135 agA/agG 0 +TMEM63B UCSF GRCh37 6 44122598 44122598 + missense_variant Missense_Mutation SNP T T C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 34 33 66 0 ENST00000259746.9:c.2477T>C p.Ile826Thr p.I826T ENST00000259746 826 aTa/aCa 0 +TMPRSS11B UCSF GRCh37 4 69095151 69095151 + missense_variant Missense_Mutation SNP A A C NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 108 32 173 0 ENST00000332644.5:c.770T>G p.Ile257Ser p.I257S ENST00000332644 NM_182502.3 257 aTt/aGt 0 +TP53 UCSF GRCh37 17 7578550 7578550 + missense_variant Missense_Mutation SNP G G A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 5 47 42 0 ENST00000269305.4:c.380C>T p.Ser127Phe p.S127F ENST00000269305 NM_001126112.2 127 tCc/tTc 0 +TTN UCSF GRCh37 2 179641275 179641275 + synonymous_variant Silent SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 119 45 205 0 ENST00000589042.1:c.5316T>C p.Ser1772= p.S1772= ENST00000589042 NM_001267550.1 1772 agT/agC 0 +UGT3A1 UCSF GRCh37 5 35965819 35965819 + missense_variant Missense_Mutation SNP C C A NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 114 34 145 0 ENST00000274278.3:c.512G>T p.Gly171Val p.G171V ENST00000274278 NM_152404.3 171 gGc/gTc 0 +WFDC12 UCSF GRCh37 20 43752784 43752784 + missense_variant Missense_Mutation SNP A A G NOVEL P17_Rec1_D Untested WXS Illumina HiSeq 85 25 78 0 ENST00000372785.3:c.202T>C p.Phe68Leu p.F68L ENST00000372785 NM_080869.1 68 Ttc/Ctc 0 +AATK UCSF GRCh37 17 79095911 79095911 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 13 5 23 0 ENST00000326724.4:c.1825T>C p.Ser609Pro p.S609P ENST00000326724 NM_001080395.2 609 Tct/Cct 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 106 62 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ABHD6 UCSF GRCh37 3 58255111 58255111 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 38 15 81 0 ENST00000478253.1:c.340T>C p.Ser114Pro p.S114P ENST00000478253 114 Tcc/Ccc 0 +ANKRD57 UCSF GRCh37 2 110372925 110372925 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 10 7 32 0 ENST00000356454.3:c.859C>G p.Leu287Val p.L287V ENST00000356454 NM_023016.3 287 Ctc/Gtc 0 +APOB UCSF GRCh37 2 21230912 21230912 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 143 74 265 0 ENST00000233242.1:c.8828A>G p.Glu2943Gly p.E2943G ENST00000233242 NM_000384.2 2943 gAa/gGa 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Pri_A somatic WXS Sanger Illumina HiSeq 60 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +BRAF UCSF GRCh37 7 140453136 140453136 + missense_variant Missense_Mutation SNP A A T snp132_rs113488022 P18_Pri_A somatic WXS Sanger Illumina HiSeq 143 35 190 0 ENST00000288602.6:c.1799T>A p.Val600Glu p.V600E ENST00000288602 NM_004333.4 600 gTg/gAg 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 74 63 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C6orf204 UCSF GRCh37 6 118791763 118791763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 135 62 179 0 ENST00000368488.5:c.1968G>C p.Lys656Asn p.K656N ENST00000368488 NM_001178035.1 656 aaG/aaC 0 +CACNA1A UCSF GRCh37 19 13563763 13563763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 124 92 300 0 ENST00000360228.5:c.466G>C p.Gly156Arg p.G156R ENST00000360228 NM_001127222.1 156 Ggg/Cgg 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 111 61 161 0 ENST00000545336.1:c.412A>G p.Ile138Val p.I138V ENST00000545336 138 Att/Gtt 0 +CCT8L2 UCSF GRCh37 22 17071975 17071975 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 142 67 253 0 ENST00000359963.3:c.1466C>T p.Ala489Val p.A489V ENST00000359963 NM_014406.4 489 gCc/gTc 0 +CDKAL1 UCSF GRCh37 6 21201505 21201505 + missense_variant,splice_region_variant Missense_Mutation SNP G G C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 98 39 165 0 ENST00000274695.4:c.1548G>C p.Lys516Asn p.K516N ENST00000274695 NM_017774.3 516 aaG/aaC 0 +CHRNA7 UCSF GRCh37 15 32393502 32393510 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS GAAGGATGA GAAGGATGA TTAAGGGTGG NOVEL P18_Pri_A Untested WXS Illumina HiSeq 6 0 ENST00000454250.3:c.283-4_287delinsTTAAGGGTGG p.X95_splice ENST00000454250 NM_001190455.2 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 16 8 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DLEC1 UCSF GRCh37 3 38141899 38141899 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 79 34 155 0 ENST00000308059.6:c.2847G>A p.Val949= p.V949= ENST00000308059 949 gtG/gtA 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 21 95 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 78 63 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +ECEL1 UCSF GRCh37 2 233348784 233348784 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 99 11 125 2 ENST00000304546.1:c.1334C>A p.Ala445Asp p.A445D ENST00000304546 NM_004826.2 445 gCc/gAc 0 +EGF UCSF GRCh37 4 110932410 110932410 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 83 37 148 0 ENST00000265171.5:c.3423C>T p.Gly1141= p.G1141= ENST00000265171 NM_001963.4 1141 ggC/ggT 0 +ETHE1 UCSF GRCh37 19 44011007 44011007 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 94 17 94 0 ENST00000292147.2:c.760G>T p.Ala254Ser p.A254S ENST00000292147 NM_014297.3 254 Gcc/Tcc 0 +FAM189A2 UCSF GRCh37 9 71986494 71986494 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 73 51 213 0 ENST00000257515.8:c.92A>G p.Gln31Arg p.Q31R ENST00000257515 NM_004816.3 31 cAg/cGg 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 124 76 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 142 89 226 0 ENST00000419119.1:c.1599A>G p.Thr533= p.T533= ENST00000419119 533 acA/acG 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 126 60 247 0 ENST00000490882.1:c.6324C>G p.Asp2108Glu p.D2108E ENST00000490882 NM_001164317.1 2108 gaC/gaG 0 +FMN1 UCSF GRCh37 15 33261055 33261055 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 41 8 65 1 ENST00000334528.9:c.2178A>C p.Pro726= p.P726= ENST00000334528 NM_001103184.3 726 ccA/ccC 0 +GATA5 UCSF GRCh37 20 61048578 61048578 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 17 8 17 0 ENST00000252997.2:c.580G>A p.Ala194Thr p.A194T ENST00000252997 NM_080473.4 194 Gcc/Acc 0 +GMNC UCSF GRCh37 3 190578563 190578563 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 105 54 167 0 ENST00000442080.1:c.88A>T p.Ser30Cys p.S30C ENST00000442080 NM_001146686.2 30 Agt/Tgt 0 +GRM1 UCSF GRCh37 6 146755345 146755345 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 68 9 113 0 ENST00000361719.2:c.2998A>G p.Thr1000Ala p.T1000A ENST00000361719 1000 Acc/Gcc 0 +HEATR4 UCSF GRCh37 14 73989203 73989203 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 79 17 123 0 ENST00000553558.1:c.654C>T p.Ile218= p.I218= ENST00000553558 NM_001220484.1 218 atC/atT 0 +HOXC12 UCSF GRCh37 12 54350163 54350163 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 106 50 213 0 ENST00000243103.3:c.662A>G p.Tyr221Cys p.Y221C ENST00000243103 NM_173860.1 221 tAt/tGt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 67 51 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGSF10 UCSF GRCh37 3 151154586 151154586 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 104 56 197 0 ENST00000282466.3:c.7763G>T p.Gly2588Val p.G2588V ENST00000282466 NM_178822.4 2588 gGt/gTt 0 +INPPL1 UCSF GRCh37 11 71949087 71949087 + missense_variant,splice_region_variant Missense_Mutation SNP C C A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 14 7 21 0 ENST00000298229.2:c.3554C>A p.Ala1185Asp p.A1185D ENST00000298229 NM_001567.3 1185 gCt/gAt 0 +IRF2BPL UCSF GRCh37 14 77492740 77492740 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 35 10 58 0 ENST00000238647.3:c.1396C>A p.His466Asn p.H466N ENST00000238647 NM_024496.3 466 Cac/Aac 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 102 41 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +NPTN UCSF GRCh37 15 73884321 73884321 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 184 28 265 0 ENST00000345330.4:c.597C>A p.Ser199Arg p.S199R ENST00000345330 NM_012428.3 199 agC/agA 0 +NUP188 UCSF GRCh37 9 131755524 131755524 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 83 53 186 0 ENST00000372577.2:c.2689A>T p.Ile897Phe p.I897F ENST00000372577 NM_015354.2 897 Att/Ttt 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 87 47 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR51T1 UCSF GRCh37 11 4903156 4903156 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 34 71 170 0 ENST00000380378.1:c.108G>A p.Ser36= p.S36= ENST00000380378 NM_001004759.1 36 tcG/tcA 0 +OR5B3 UCSF GRCh37 11 58170636 58170636 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 145 73 217 1 ENST00000309403.2:c.247T>A p.Phe83Ile p.F83I ENST00000309403 NM_001005469.1 83 Ttc/Atc 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 126 94 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +OR6C70 UCSF GRCh37 12 55863388 55863388 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 207 36 262 0 ENST00000327335.4:c.535A>G p.Ile179Val p.I179V ENST00000327335 NM_001005499.1 179 Att/Gtt 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 125 45 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PRPF40A UCSF GRCh37 2 153527822 153527822 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 146 107 242 0 ENST00000410080.1:c.1444G>A p.Glu482Lys p.E482K ENST00000410080 NM_017892.3 482 Gaa/Aaa 0 +RACGAP1 UCSF GRCh37 12 50387942 50387942 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 98 54 222 0 ENST00000434422.1:c.1311C>T p.Arg437= p.R437= ENST00000434422 437 cgC/cgT 0 +RAI14 UCSF GRCh37 5 34824590 34824590 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 69 34 110 0 ENST00000515799.1:c.2652T>C p.Asp884= p.D884= ENST00000515799 NM_001145525.1 884 gaT/gaC 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 90 45 117 0 ENST00000311549.6:c.398C>T p.Ala133Val p.A133V ENST00000311549 NM_000982.3 133 gCt/gTt 0 +RYR1 UCSF GRCh37 19 38991267 38991267 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 62 14 84 0 ENST00000359596.3:c.7345G>A p.Glu2449Lys p.E2449K ENST00000359596 2449 Gag/Aag 0 +SIGLEC12 UCSF GRCh37 19 52004795 52004795 + frameshift_variant Frame_Shift_Ins INS G G CT NOVEL P18_Pri_A Untested WXS Illumina HiSeq 7 0 ENST00000291707.3:c.193delinsAG p.Ala66GlyfsTer50 p.A66Gfs*50 ENST00000291707 NM_053003.2 65 Cgg/AGgg 0 +SORT1 UCSF GRCh37 1 109890108 109890108 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 98 36 89 0 ENST00000256637.6:c.829T>A p.Cys277Ser p.C277S ENST00000256637 NM_002959.5 277 Tgc/Agc 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 94 57 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +SULT1A1 UCSF GRCh37 16 28617217 28617217 + synonymous_variant Silent SNP C C T snp132_rs11569762 P18_Pri_A Untested WXS Illumina HiSeq 67 13 101 0 ENST00000395609.1:c.813G>A p.Ala271= p.A271= ENST00000395609 271 gcG/gcA 0 +TAAR8 UCSF GRCh37 6 132874197 132874197 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 111 72 267 0 ENST00000275200.1:c.366G>T p.Leu122Phe p.L122F ENST00000275200 NM_053278.1 122 ttG/ttT 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 32 21 79 0 ENST00000589378.1:c.1399G>C p.Val467Leu p.V467L ENST00000589378 NM_001267561.1 467 Gtg/Ctg 0 +TMEM201 UCSF GRCh37 1 9658524 9658524 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 44 21 97 0 ENST00000340381.6:c.447G>T p.Glu149Asp p.E149D ENST00000340381 NM_001130924.2 149 gaG/gaT 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 110 76 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_A somatic WXS Sanger Illumina HiSeq 19 50 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 101 52 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_A Untested WXS Illumina HiSeq 105 48 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +TRIM59 UCSF GRCh37 3 160156368 160156369 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P18_Pri_A Untested WXS Illumina HiSeq 6 0 ENST00000309784.4:c.604dup p.Ser202LysfsTer8 p.S202Kfs*8 ENST00000309784 NM_173084.2 201 -/A 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 114 78 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +WDR1 UCSF GRCh37 4 10089922 10089922 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 10 6 27 0 ENST00000499869.2:c.712T>G p.Tyr238Asp p.Y238D ENST00000499869 238 Tac/Gac 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 135 75 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_A Untested WXS Illumina HiSeq 86 49 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +ZNF518B UCSF GRCh37 4 10445063 10445063 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_A Untested WXS Illumina HiSeq 149 29 233 0 ENST00000326756.3:c.2890A>T p.Asn964Tyr p.N964Y ENST00000326756 NM_053042.2 964 Aat/Tat 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 80 31 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ADAM19 UCSF GRCh37 5 156934130 156934130 + synonymous_variant Silent SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 52 9 87 1 ENST00000257527.4:c.924C>A p.Gly308= p.G308= ENST00000257527 NM_033274.4 308 ggC/ggA 0 +ANGPT4 UCSF GRCh37 20 858877 858877 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 37 16 62 0 ENST00000381922.3:c.1147C>A p.Gln383Lys p.Q383K ENST00000381922 NM_015985.2 383 Caa/Aaa 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 19 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +C14orf49 UCSF GRCh37 14 95932381 95932381 + synonymous_variant Silent SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 106 41 119 0 ENST00000334258.5:c.514C>A p.Arg172= p.R172= ENST00000334258 NM_152592.3 172 Cgg/Agg 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 88 24 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C4BPA UCSF GRCh37 1 207317200 207317200 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 89 26 161 0 ENST00000367070.3:c.1482G>T p.Leu494Phe p.L494F ENST00000367070 NM_000715.3 494 ttG/ttT 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 106 44 161 0 ENST00000545336.1:c.412A>G p.Ile138Val p.I138V ENST00000545336 138 Att/Gtt 0 +CELA2A UCSF GRCh37 1 15789929 15789929 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 143 47 211 0 ENST00000359621.4:c.405C>A p.Asp135Glu p.D135E ENST00000359621 NM_033440.2 135 gaC/gaA 0 +CILP2 UCSF GRCh37 19 19655073 19655073 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 149 18 142 0 ENST00000291495.5:c.1719C>T p.Gly573= p.G573= ENST00000291495 NM_153221.2 573 ggC/ggT 0 +CRNN UCSF GRCh37 1 152382931 152382931 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 286 54 276 0 ENST00000271835.3:c.627G>C p.Glu209Asp p.E209D ENST00000271835 NM_016190.2 209 gaG/gaC 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 24 6 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 62 87 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 63 30 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +EFR3A UCSF GRCh37 8 132980635 132980635 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 214 38 283 0 ENST00000254624.5:c.949G>T p.Val317Phe p.V317F ENST00000254624 NM_015137.4 317 Gtt/Ttt 0 +FAM81B UCSF GRCh37 5 94731872 94731872 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 146 26 197 0 ENST00000283357.5:c.286G>T p.Val96Phe p.V96F ENST00000283357 NM_152548.2 96 Gtt/Ttt 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 222 74 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 158 72 226 0 ENST00000419119.1:c.1599A>G p.Thr533= p.T533= ENST00000419119 533 acA/acG 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 202 59 247 0 ENST00000490882.1:c.6324C>G p.Asp2108Glu p.D2108E ENST00000490882 NM_001164317.1 2108 gaC/gaG 0 +GPR158 UCSF GRCh37 10 25701295 25701295 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 304 42 301 0 ENST00000376351.3:c.1228G>A p.Val410Ile p.V410I ENST00000376351 NM_020752.2 410 Gtc/Atc 0 +GPRIN2 UCSF GRCh37 10 46999601 46999601 + missense_variant Missense_Mutation SNP G G A snp132_rs9422022 P18_Pri_B Untested WXS Illumina HiSeq 62 19 73 1 ENST00000374314.4:c.721G>A p.Val241Met p.V241M ENST00000374314 241 Gtg/Atg 0 +HOXC12 UCSF GRCh37 12 54350163 54350163 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 117 38 213 0 ENST00000243103.3:c.662A>G p.Tyr221Cys p.Y221C ENST00000243103 NM_173860.1 221 tAt/tGt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 79 33 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KIAA0513 UCSF GRCh37 16 85111032 85111032 + splice_region_variant,synonymous_variant Splice_Region SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 31 7 66 0 ENST00000566428.1:c.576A>G p.Gly192= p.G192= ENST00000566428 NM_001286565.1 192 ggA/ggG 0 +KRTAP4-7 UCSF GRCh37 17 39240829 39240829 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 57 10 64 0 ENST00000391417.4:c.371T>C p.Val124Ala p.V124A ENST00000391417 NM_033061.3 124 gTc/gCc 0 +LAMC2 UCSF GRCh37 1 183212454 183212454 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 119 17 161 0 ENST00000264144.4:c.3501G>C p.Leu1167= p.L1167= ENST00000264144 NM_005562.2 1167 ctG/ctC 0 +LRRIQ3 UCSF GRCh37 1 74507485 74507485 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 111 45 208 0 ENST00000354431.4:c.1130T>C p.Phe377Ser p.F377S ENST00000354431 NM_001105659.1 377 tTt/tCt 0 +LRRK1 UCSF GRCh37 15 101566207 101566207 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 52 87 118 0 ENST00000388948.3:c.2270C>T p.Thr757Met p.T757M ENST00000388948 NM_024652.3 757 aCg/aTg 0 +LTBP3 UCSF GRCh37 11 65321611 65321611 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 32 12 39 0 ENST00000301873.5:c.572T>C p.Ile191Thr p.I191T ENST00000301873 NM_001130144.2 191 aTc/aCc 0 +MAD1L1 UCSF GRCh37 7 2020096 2020096 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.015,snp132_rs113127342 P18_Pri_B Untested WXS Illumina HiSeq 15 3 35 1 ENST00000406869.1:c.1497C>T p.Asp499= p.D499= ENST00000406869 499 gaC/gaT 0 +MAGEA8 UCSF GRCh37 X 149013393 149013393 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 78 39 126 0 ENST00000535454.1:c.347T>C p.Val116Ala p.V116A ENST00000535454 NM_001166400.1 116 gTg/gCg 0 +MET UCSF GRCh37 7 116339260 116339260 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 103 58 182 0 ENST00000397752.3:c.122A>G p.Tyr41Cys p.Y41C ENST00000397752 NM_000245.2 41 tAt/tGt 0 +METTL11B UCSF GRCh37 1 170135792 170135792 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 180 95 238 0 ENST00000439373.2:c.480G>A p.Gln160= p.Q160= ENST00000439373 NM_001136107.1 160 caG/caA 0 +MTUS1 UCSF GRCh37 8 17611815 17611815 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 230 117 292 0 ENST00000262102.6:c.1502G>A p.Ser501Asn p.S501N ENST00000262102 NM_001001924.2 501 aGt/aAt 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 109 60 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +NTN1 UCSF GRCh37 17 9066252 9066252 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 33 6 42 0 ENST00000173229.2:c.1141C>G p.His381Asp p.H381D ENST00000173229 NM_004822.2 381 Cat/Gat 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 159 71 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 229 104 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +PCLO UCSF GRCh37 7 82581498 82581499 + inframe_insertion In_Frame_Ins INS - - TCT NOVEL P18_Pri_B Untested WXS Illumina HiSeq 6 0 ENST00000333891.9:c.8770_8771insAGA p.Ile2923_Ile2924insLys p.I2923_I2924insK ENST00000333891 NM_033026.5 2924 ata/aAGAta 0 +PCNT UCSF GRCh37 21 47831434 47831434 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 52 8 66 1 ENST00000359568.5:c.5447C>A p.Ala1816Asp p.A1816D ENST00000359568 NM_006031.5 1816 gCc/gAc 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 126 49 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PKHD1L1 UCSF GRCh37 8 110457191 110457191 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 276 104 305 0 ENST00000378402.5:c.5093T>C p.Phe1698Ser p.F1698S ENST00000378402 NM_177531.4 1698 tTc/tCc 0 +PPP1R11 UCSF GRCh37 6 30037034 30037034 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 63 9 76 0 ENST00000376772.3:c.332C>T p.Pro111Leu p.P111L ENST00000376772 NM_021959.2 111 cCc/cTc 0 +PRR12 UCSF GRCh37 19 50100979 50100979 + synonymous_variant Silent SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 31 7 43 0 ENST00000418929.2:c.3387C>G p.Arg1129= p.R1129= ENST00000418929 NM_020719.1 1129 cgC/cgG 0 +QRFPR UCSF GRCh37 4 122257975 122257975 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 221 29 259 0 ENST00000394427.2:c.548T>C p.Val183Ala p.V183A ENST00000394427 NM_198179.2 183 gTg/gCg 0 +RAB11FIP1 UCSF GRCh37 8 37756731 37756731 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 6 8 20 0 ENST00000330843.4:c.229C>T p.Leu77= p.L77= ENST00000330843 NM_001002814.2 77 Ctg/Ttg 0 +RACGAP1 UCSF GRCh37 12 50387942 50387942 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 116 22 222 0 ENST00000434422.1:c.1311C>T p.Arg437= p.R437= ENST00000434422 437 cgC/cgT 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 53 16 117 0 ENST00000311549.6:c.398C>T p.Ala133Val p.A133V ENST00000311549 NM_000982.3 133 gCt/gTt 0 +SON UCSF GRCh37 21 34923851 34923851 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 278 41 324 0 ENST00000356577.4:c.2314G>T p.Asp772Tyr p.D772Y ENST00000356577 NM_138927.2 772 Gac/Tac 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 123 45 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +SRCAP UCSF GRCh37 16 30720835 30720835 + missense_variant,splice_region_variant Missense_Mutation SNP T T G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 76 18 111 2 ENST00000262518.4:c.635T>G p.Val212Gly p.V212G ENST00000262518 NM_006662.2 212 gTg/gGg 0 +TBL1X UCSF GRCh37 X 9652214 9652214 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 22 8 61 0 ENST00000217964.7:c.343A>G p.Ile115Val p.I115V ENST00000217964 NM_005647.3 115 Atc/Gtc 0 +TFAP2C UCSF GRCh37 20 55206427 55206427 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 37 9 59 0 ENST00000201031.2:c.215C>T p.Ser72Leu p.S72L ENST00000201031 NM_003222.3 72 tCg/tTg 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 57 26 79 0 ENST00000589378.1:c.1399G>C p.Val467Leu p.V467L ENST00000589378 NM_001267561.1 467 Gtg/Ctg 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 79 32 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 18 39 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 193 91 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 198 89 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +TTF2 UCSF GRCh37 1 117626650 117626650 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_B Untested WXS Illumina HiSeq 137 47 185 0 ENST00000369466.4:c.1914C>G p.Asp638Glu p.D638E ENST00000369466 NM_003594.3 638 gaC/gaG 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Pri_B Untested WXS Illumina HiSeq 182 67 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +WWC2 UCSF GRCh37 4 184129248 184129248 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_B Untested WXS Illumina HiSeq 115 42 211 0 ENST00000403733.3:c.384C>T p.Ala128= p.A128= ENST00000403733 NM_024949.5 128 gcC/gcT 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 161 26 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_B Untested WXS Illumina HiSeq 60 14 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +AATK UCSF GRCh37 17 79095911 79095911 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 9 12 23 0 ENST00000326724.4:c.1825T>C p.Ser609Pro p.S609P ENST00000326724 NM_001080395.2 609 Tct/Cct 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 88 45 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ABHD6 UCSF GRCh37 3 58255111 58255111 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 54 14 81 0 ENST00000478253.1:c.340T>C p.Ser114Pro p.S114P ENST00000478253 114 Tcc/Ccc 0 +ALOX15 UCSF GRCh37 17 4542725 4542725 + missense_variant,splice_region_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.060,snp132_rs41509647 P18_Pri_C Untested WXS Illumina HiSeq 53 6 79 2 ENST00000570836.1:c.337G>A p.Gly113Ser p.G113S ENST00000570836 113 Ggc/Agc 0 +ANKRD57 UCSF GRCh37 2 110372925 110372925 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 17 22 32 0 ENST00000356454.3:c.859C>G p.Leu287Val p.L287V ENST00000356454 NM_023016.3 287 Ctc/Gtc 0 +APOB UCSF GRCh37 2 21230912 21230912 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 185 122 265 0 ENST00000233242.1:c.8828A>G p.Glu2943Gly p.E2943G ENST00000233242 NM_000384.2 2943 gAa/gGa 0 +APOBR UCSF GRCh37 16 28507445 28507445 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 11 5 32 0 ENST00000564831.1:c.1083G>C p.Glu361Asp p.E361D ENST00000564831 NM_018690.3 361 gaG/gaC 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 58 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 87 42 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C6orf204 UCSF GRCh37 6 118791763 118791763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 95 37 179 0 ENST00000368488.5:c.1968G>C p.Lys656Asn p.K656N ENST00000368488 NM_001178035.1 656 aaG/aaC 0 +CACNA1A UCSF GRCh37 19 13563763 13563763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 290 171 300 0 ENST00000360228.5:c.466G>C p.Gly156Arg p.G156R ENST00000360228 NM_001127222.1 156 Ggg/Cgg 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 89 54 161 0 ENST00000545336.1:c.412A>G p.Ile138Val p.I138V ENST00000545336 138 Att/Gtt 0 +CCT8L2 UCSF GRCh37 22 17071975 17071975 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 180 102 253 0 ENST00000359963.3:c.1466C>T p.Ala489Val p.A489V ENST00000359963 NM_014406.4 489 gCc/gTc 0 +CDKAL1 UCSF GRCh37 6 21201505 21201505 + missense_variant,splice_region_variant Missense_Mutation SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 146 25 165 0 ENST00000274695.4:c.1548G>C p.Lys516Asn p.K516N ENST00000274695 NM_017774.3 516 aaG/aaC 0 +CHRM2 UCSF GRCh37 7 136700565 136700565 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 169 34 184 0 ENST00000445907.2:c.953A>G p.Glu318Gly p.E318G ENST00000445907 NM_001006627.1 318 gAg/gGg 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 21 17 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DLEC1 UCSF GRCh37 3 38141899 38141899 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 124 22 155 0 ENST00000308059.6:c.2847G>A p.Val949= p.V949= ENST00000308059 949 gtG/gtA 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 30 125 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 83 55 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +EGF UCSF GRCh37 4 110932410 110932410 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 98 62 148 0 ENST00000265171.5:c.3423C>T p.Gly1141= p.G1141= ENST00000265171 NM_001963.4 1141 ggC/ggT 0 +F2 UCSF GRCh37 11 46751000 46751000 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 108 13 132 0 ENST00000311907.5:c.1543G>A p.Val515Ile p.V515I ENST00000311907 NM_000506.3 515 Gtt/Att 0 +FAM129A UCSF GRCh37 1 184764507 184764529 + frameshift_variant Frame_Shift_Ins INS CGGAGAGGCTGGGCTGCCTACCT CGGAGAGGCTGGGCTGCCTACCT GGGGGGGGCTGGGGTGCCCACCCC NOVEL P18_Pri_C Untested WXS Illumina HiSeq 8 0 ENST00000367511.3:c.2369_2391delinsGGGGTGGGCACCCCAGCCCCCCCC p.Glu790GlyfsTer37 p.E790Gfs*37 ENST00000367511 NM_052966.3 790 gAGGTAGGCAGCCCAGCCTCTCCG/gGGGGTGGGCACCCCAGCCCCCCCC 0 +FAM189A2 UCSF GRCh37 9 71986494 71986494 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 145 62 213 0 ENST00000257515.8:c.92A>G p.Gln31Arg p.Q31R ENST00000257515 NM_004816.3 31 cAg/cGg 0 +FAM47C UCSF GRCh37 X 37028925 37028925 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 79 14 100 0 ENST00000358047.3:c.2442G>A p.Pro814= p.P814= ENST00000358047 NM_001013736.2 814 ccG/ccA 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 214 163 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 147 110 226 0 ENST00000419119.1:c.1599A>G p.Thr533= p.T533= ENST00000419119 533 acA/acG 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 188 104 247 0 ENST00000490882.1:c.6324C>G p.Asp2108Glu p.D2108E ENST00000490882 NM_001164317.1 2108 gaC/gaG 0 +GATA5 UCSF GRCh37 20 61048578 61048578 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 10 7 17 0 ENST00000252997.2:c.580G>A p.Ala194Thr p.A194T ENST00000252997 NM_080473.4 194 Gcc/Acc 0 +GMNC UCSF GRCh37 3 190578563 190578563 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 112 80 167 0 ENST00000442080.1:c.88A>T p.Ser30Cys p.S30C ENST00000442080 NM_001146686.2 30 Agt/Tgt 0 +GP2 UCSF GRCh37 16 20337743 20337743 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 34 8 80 0 ENST00000381362.4:c.11T>G p.Leu4Arg p.L4R ENST00000381362 NM_001007240.1 4 cTt/cGt 0 +GPRIN2 UCSF GRCh37 10 46999601 46999601 + missense_variant Missense_Mutation SNP G G A snp132_rs9422022 P18_Pri_C Untested WXS Illumina HiSeq 86 20 73 1 ENST00000374314.4:c.721G>A p.Val241Met p.V241M ENST00000374314 241 Gtg/Atg 0 +HOXC12 UCSF GRCh37 12 54350163 54350163 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 116 86 213 0 ENST00000243103.3:c.662A>G p.Tyr221Cys p.Y221C ENST00000243103 NM_173860.1 221 tAt/tGt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 58 55 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFT74 UCSF GRCh37 9 26980584 26980584 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P18_Pri_C Untested WXS Illumina HiSeq 10 0 ENST00000443698.1:c.275del p.Leu92Ter p.L92* ENST00000443698 NM_001099222.1 91 aTt/at 0 +IGSF10 UCSF GRCh37 3 151154586 151154586 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 180 23 197 0 ENST00000282466.3:c.7763G>T p.Gly2588Val p.G2588V ENST00000282466 NM_178822.4 2588 gGt/gTt 0 +KRAS UCSF GRCh37 12 25398220 25398220 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 32 4 45 0 ENST00000256078.4:c.99T>G p.Asp33Glu p.D33E ENST00000256078 NM_033360.2 33 gaT/gaG 0 +MKI67 UCSF GRCh37 10 129905112 129905113 + frameshift_variant Frame_Shift_Del DEL TG TG - 1000g2010nov_all P18_Pri_C Untested WXS Illumina HiSeq 7 0 ENST00000368654.3:c.4991_4992delCA p.Thr1664ArgfsTer7 p.T1664Rfs*7 ENST00000368654 NM_002417.4 1664 aCA/a 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 142 93 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +NOTCH1 UCSF GRCh37 9 139412283 139412285 + inframe_deletion In_Frame_Del DEL GTT GTT - NOVEL P18_Pri_C Untested WXS Illumina HiSeq 7 0 ENST00000277541.6:c.1360_1362delAAC p.Asn454del p.N454del ENST00000277541 NM_017617.3 454 AAC/- 0 +NUP188 UCSF GRCh37 9 131755524 131755524 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 108 57 186 0 ENST00000372577.2:c.2689A>T p.Ile897Phe p.I897F ENST00000372577 NM_015354.2 897 Att/Ttt 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 153 94 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR51T1 UCSF GRCh37 11 4903156 4903156 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 29 64 170 0 ENST00000380378.1:c.108G>A p.Ser36= p.S36= ENST00000380378 NM_001004759.1 36 tcG/tcA 0 +OR5B3 UCSF GRCh37 11 58170636 58170636 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 243 32 217 1 ENST00000309403.2:c.247T>A p.Phe83Ile p.F83I ENST00000309403 NM_001005469.1 83 Ttc/Atc 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 219 160 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +OR6C70 UCSF GRCh37 12 55863388 55863388 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 255 30 262 0 ENST00000327335.4:c.535A>G p.Ile179Val p.I179V ENST00000327335 NM_001005499.1 179 Att/Gtt 0 +PAGE4 UCSF GRCh37 X 49595090 49595090 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 76 23 133 0 ENST00000218068.6:c.59A>T p.Asp20Val p.D20V ENST00000218068 NM_007003.2 20 gAt/gTt 0 +PCLO UCSF GRCh37 7 82581498 82581499 + inframe_insertion In_Frame_Ins INS - - TCT NOVEL P18_Pri_C Untested WXS Illumina HiSeq 10 0 ENST00000333891.9:c.8770_8771insAGA p.Ile2923_Ile2924insLys p.I2923_I2924insK ENST00000333891 NM_033026.5 2924 ata/aAGAta 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 174 66 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PRPF40A UCSF GRCh37 2 153527822 153527822 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 99 87 242 0 ENST00000410080.1:c.1444G>A p.Glu482Lys p.E482K ENST00000410080 NM_017892.3 482 Gaa/Aaa 0 +RACGAP1 UCSF GRCh37 12 50387942 50387942 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 119 76 222 0 ENST00000434422.1:c.1311C>T p.Arg437= p.R437= ENST00000434422 437 cgC/cgT 0 +RAF1 UCSF GRCh37 3 12645699 12645699 + missense_variant Missense_Mutation SNP G G A snp132_rs80338796 P18_Pri_C Untested WXS Illumina HiSeq 82 18 152 0 ENST00000251849.4:c.770C>T p.Ser257Leu p.S257L ENST00000251849 NM_002880.3 257 tCg/tTg 0 +RAI14 UCSF GRCh37 5 34824590 34824590 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 24 22 110 0 ENST00000515799.1:c.2652T>C p.Asp884= p.D884= ENST00000515799 NM_001145525.1 884 gaT/gaC 0 +RASAL3 UCSF GRCh37 19 15567379 15567379 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 99 12 106 0 ENST00000343625.7:c.1510T>C p.Leu504= p.L504= ENST00000343625 NM_022904.1 504 Ttg/Ctg 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 53 29 117 0 ENST00000311549.6:c.398C>T p.Ala133Val p.A133V ENST00000311549 NM_000982.3 133 gCt/gTt 0 +RYR1 UCSF GRCh37 19 38991267 38991267 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 81 11 84 0 ENST00000359596.3:c.7345G>A p.Glu2449Lys p.E2449K ENST00000359596 2449 Gag/Aag 0 +SNAP91 UCSF GRCh37 6 84315432 84315432 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 33 5 54 0 ENST00000439399.2:c.1113A>C p.Pro371= p.P371= ENST00000439399 NM_014841.2 371 ccA/ccC 0 +SORT1 UCSF GRCh37 1 109890108 109890108 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 78 26 89 0 ENST00000256637.6:c.829T>A p.Cys277Ser p.C277S ENST00000256637 NM_002959.5 277 Tgc/Agc 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 97 72 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +TAAR8 UCSF GRCh37 6 132874197 132874197 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 337 179 267 0 ENST00000275200.1:c.366G>T p.Leu122Phe p.L122F ENST00000275200 NM_053278.1 122 ttG/ttT 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 67 43 79 0 ENST00000589378.1:c.1399G>C p.Val467Leu p.V467L ENST00000589378 NM_001267561.1 467 Gtg/Ctg 0 +TLR7 UCSF GRCh37 X 12905935 12905935 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 69 11 131 0 ENST00000380659.3:c.2308A>T p.Asn770Tyr p.N770Y ENST00000380659 NM_016562.3 770 Aat/Tat 0 +TMEM201 UCSF GRCh37 1 9658524 9658524 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 45 26 97 0 ENST00000340381.6:c.447G>T p.Glu149Asp p.E149D ENST00000340381 NM_001130924.2 149 gaG/gaT 0 +TMLHE UCSF GRCh37 X 154743884 154743884 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 94 14 128 1 ENST00000334398.3:c.401T>G p.Val134Gly p.V134G ENST00000334398 NM_018196.3 134 gTg/gGg 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 89 52 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 9 66 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 185 161 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_C Untested WXS Illumina HiSeq 187 166 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +TUBA3D UCSF GRCh37 2 132238306 132238306 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_C Untested WXS Illumina HiSeq 193 29 160 2 ENST00000321253.6:c.1040G>T p.Cys347Phe p.C347F ENST00000321253 NM_080386.3 347 tGc/tTc 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Pri_C Untested WXS Illumina HiSeq 164 110 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +WDR1 UCSF GRCh37 4 10089922 10089922 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 17 4 27 0 ENST00000499869.2:c.712T>G p.Tyr238Asp p.Y238D ENST00000499869 238 Tac/Gac 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 161 89 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_C Untested WXS Illumina HiSeq 72 41 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +AATK UCSF GRCh37 17 79095911 79095911 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 18 5 23 0 ENST00000326724.4:c.1825T>C p.Ser609Pro p.S609P ENST00000326724 NM_001080395.2 609 Tct/Cct 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 91 45 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ABHD6 UCSF GRCh37 3 58255111 58255111 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 45 18 81 0 ENST00000478253.1:c.340T>C p.Ser114Pro p.S114P ENST00000478253 114 Tcc/Ccc 0 +ANKRD57 UCSF GRCh37 2 110372925 110372925 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 30 17 32 0 ENST00000356454.3:c.859C>G p.Leu287Val p.L287V ENST00000356454 NM_023016.3 287 Ctc/Gtc 0 +APOB UCSF GRCh37 2 21230912 21230912 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 226 123 265 0 ENST00000233242.1:c.8828A>G p.Glu2943Gly p.E2943G ENST00000233242 NM_000384.2 2943 gAa/gGa 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 48 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +BCAP31 UCSF GRCh37 X 152986398 152986398 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 89 10 93 1 ENST00000458587.2:c.323T>G p.Val108Gly p.V108G ENST00000458587 NM_001139441.1 108 gTg/gGg 0 +BRAF UCSF GRCh37 7 140453136 140453136 + missense_variant Missense_Mutation SNP A A T snp132_rs113488022 P18_Pri_D somatic WXS Sanger Illumina HiSeq 159 22 190 0 ENST00000288602.6:c.1799T>A p.Val600Glu p.V600E ENST00000288602 NM_004333.4 600 gTg/gAg 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 68 39 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C6orf204 UCSF GRCh37 6 118791763 118791763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 134 53 179 0 ENST00000368488.5:c.1968G>C p.Lys656Asn p.K656N ENST00000368488 NM_001178035.1 656 aaG/aaC 0 +CACNA1A UCSF GRCh37 19 13563763 13563763 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 378 193 300 0 ENST00000360228.5:c.466G>C p.Gly156Arg p.G156R ENST00000360228 NM_001127222.1 156 Ggg/Cgg 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 92 50 161 0 ENST00000545336.1:c.412A>G p.Ile138Val p.I138V ENST00000545336 138 Att/Gtt 0 +CCT8L2 UCSF GRCh37 22 17071975 17071975 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 228 117 253 0 ENST00000359963.3:c.1466C>T p.Ala489Val p.A489V ENST00000359963 NM_014406.4 489 gCc/gTc 0 +CDKAL1 UCSF GRCh37 6 21201505 21201505 + missense_variant,splice_region_variant Missense_Mutation SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 122 35 165 0 ENST00000274695.4:c.1548G>C p.Lys516Asn p.K516N ENST00000274695 NM_017774.3 516 aaG/aaC 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 27 11 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DLEC1 UCSF GRCh37 3 38141899 38141899 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 102 25 155 0 ENST00000308059.6:c.2847G>A p.Val949= p.V949= ENST00000308059 949 gtG/gtA 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 57 111 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 79 51 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +EGF UCSF GRCh37 4 110932410 110932410 + synonymous_variant Silent SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 99 28 148 0 ENST00000265171.5:c.3423C>T p.Gly1141= p.G1141= ENST00000265171 NM_001963.4 1141 ggC/ggT 0 +FAM189A2 UCSF GRCh37 9 71986494 71986494 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 166 52 213 0 ENST00000257515.8:c.92A>G p.Gln31Arg p.Q31R ENST00000257515 NM_004816.3 31 cAg/cGg 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 292 130 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 192 93 226 0 ENST00000419119.1:c.1599A>G p.Thr533= p.T533= ENST00000419119 533 acA/acG 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 238 96 247 0 ENST00000490882.1:c.6324C>G p.Asp2108Glu p.D2108E ENST00000490882 NM_001164317.1 2108 gaC/gaG 0 +GMNC UCSF GRCh37 3 190578563 190578563 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 157 67 167 0 ENST00000442080.1:c.88A>T p.Ser30Cys p.S30C ENST00000442080 NM_001146686.2 30 Agt/Tgt 0 +GPRIN2 UCSF GRCh37 10 46999601 46999601 + missense_variant Missense_Mutation SNP G G A snp132_rs9422022 P18_Pri_D Untested WXS Illumina HiSeq 89 11 73 1 ENST00000374314.4:c.721G>A p.Val241Met p.V241M ENST00000374314 241 Gtg/Atg 0 +HOXC12 UCSF GRCh37 12 54350163 54350163 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 160 71 213 0 ENST00000243103.3:c.662A>G p.Tyr221Cys p.Y221C ENST00000243103 NM_173860.1 221 tAt/tGt 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 83 37 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGSF10 UCSF GRCh37 3 151154586 151154586 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 141 46 197 0 ENST00000282466.3:c.7763G>T p.Gly2588Val p.G2588V ENST00000282466 NM_178822.4 2588 gGt/gTt 0 +JUNB UCSF GRCh37 19 12903427 12903427 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 14 5 14 0 ENST00000302754.4:c.842C>G p.Ala281Gly p.A281G ENST00000302754 NM_002229.2 281 gCg/gGg 0 +MED8 UCSF GRCh37 1 43850143 43850144 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 6 0 ENST00000290663.6:c.884dup p.Asn295LysfsTer19 p.N295Kfs*19 ENST00000290663 NM_052877.4 295 aat/aAat 0 +MKI67 UCSF GRCh37 10 129905112 129905113 + frameshift_variant Frame_Shift_Del DEL TG TG - 1000g2010nov_all P18_Pri_D Untested WXS Illumina HiSeq 6 0 ENST00000368654.3:c.4991_4992delCA p.Thr1664ArgfsTer7 p.T1664Rfs*7 ENST00000368654 NM_002417.4 1664 aCA/a 0 +MN1 UCSF GRCh37 22 28194166 28194166 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 38 7 40 0 ENST00000302326.4:c.2366C>G p.Pro789Arg p.P789R ENST00000302326 NM_002430.2 789 cCt/cGt 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 145 72 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +NUP188 UCSF GRCh37 9 131755524 131755524 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 125 65 186 0 ENST00000372577.2:c.2689A>T p.Ile897Phe p.I897F ENST00000372577 NM_015354.2 897 Att/Ttt 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 188 105 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR51T1 UCSF GRCh37 11 4903156 4903156 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 67 73 170 0 ENST00000380378.1:c.108G>A p.Ser36= p.S36= ENST00000380378 NM_001004759.1 36 tcG/tcA 0 +OR5B3 UCSF GRCh37 11 58170636 58170636 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 232 89 217 1 ENST00000309403.2:c.247T>A p.Phe83Ile p.F83I ENST00000309403 NM_001005469.1 83 Ttc/Atc 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 309 154 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +OR6C70 UCSF GRCh37 12 55863388 55863388 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 299 40 262 0 ENST00000327335.4:c.535A>G p.Ile179Val p.I179V ENST00000327335 NM_001005499.1 179 Att/Gtt 0 +OTOP1 UCSF GRCh37 4 4228243 4228243 + missense_variant Missense_Mutation SNP G G T 1000g2010nov_all_0.081 P18_Pri_D Untested WXS Illumina HiSeq 9 6 15 0 ENST00000296358.4:c.349C>A p.His117Asn p.H117N ENST00000296358 NM_177998.1 117 Cac/Aac 0 +PCDP1 UCSF GRCh37 2 120366070 120366085 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS CTCCCCAGGCAGGTGC CTCCCCAGGCAGGTGC TCTCCCCAGGCAGGGGG NOVEL P18_Pri_D Untested WXS Illumina HiSeq 6 0 ENST00000413369.3:c.1134-8_1141delinsTCTCCCCAGGCAGGGGG p.X378_splice ENST00000413369 NM_001271049.1 0 +PCLO UCSF GRCh37 7 82581498 82581499 + inframe_insertion In_Frame_Ins INS - - TCT NOVEL P18_Pri_D Untested WXS Illumina HiSeq 15 0 ENST00000333891.9:c.8770_8771insAGA p.Ile2923_Ile2924insLys p.I2923_I2924insK ENST00000333891 NM_033026.5 2924 ata/aAGAta 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 191 70 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PRPF40A UCSF GRCh37 2 153527822 153527822 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 155 53 242 0 ENST00000410080.1:c.1444G>A p.Glu482Lys p.E482K ENST00000410080 NM_017892.3 482 Gaa/Aaa 0 +RACGAP1 UCSF GRCh37 12 50387942 50387942 + synonymous_variant Silent SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 117 56 222 0 ENST00000434422.1:c.1311C>T p.Arg437= p.R437= ENST00000434422 437 cgC/cgT 0 +RAI14 UCSF GRCh37 5 34824590 34824590 + synonymous_variant Silent SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 50 24 110 0 ENST00000515799.1:c.2652T>C p.Asp884= p.D884= ENST00000515799 NM_001145525.1 884 gaT/gaC 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 60 44 117 0 ENST00000311549.6:c.398C>T p.Ala133Val p.A133V ENST00000311549 NM_000982.3 133 gCt/gTt 0 +RYR1 UCSF GRCh37 19 38991267 38991267 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 78 28 84 0 ENST00000359596.3:c.7345G>A p.Glu2449Lys p.E2449K ENST00000359596 2449 Gag/Aag 0 +SORT1 UCSF GRCh37 1 109890108 109890108 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 103 27 89 0 ENST00000256637.6:c.829T>A p.Cys277Ser p.C277S ENST00000256637 NM_002959.5 277 Tgc/Agc 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 127 50 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +TAAR8 UCSF GRCh37 6 132874197 132874197 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 486 179 267 0 ENST00000275200.1:c.366G>T p.Leu122Phe p.L122F ENST00000275200 NM_053278.1 122 ttG/ttT 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 90 41 79 0 ENST00000589378.1:c.1399G>C p.Val467Leu p.V467L ENST00000589378 NM_001267561.1 467 Gtg/Ctg 0 +TMEM201 UCSF GRCh37 1 9658524 9658524 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 88 30 97 0 ENST00000340381.6:c.447G>T p.Glu149Asp p.E149D ENST00000340381 NM_001130924.2 149 gaG/gaT 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 100 50 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 17 65 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 258 84 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Pri_D Untested WXS Illumina HiSeq 257 83 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +UGT1A3 UCSF GRCh37 2 234638283 234638284 + frameshift_variant Frame_Shift_Ins INS - - T NOVEL P18_Pri_D Untested WXS Illumina HiSeq 6 0 ENST00000482026.1:c.518dup p.Leu173PhefsTer7 p.L173Ffs*7 ENST00000482026 171 ttt/tTtt 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 226 101 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +WDR1 UCSF GRCh37 4 10089922 10089922 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 16 3 27 0 ENST00000499869.2:c.712T>G p.Tyr238Asp p.Y238D ENST00000499869 238 Tac/Gac 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 185 78 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Pri_D Untested WXS Illumina HiSeq 55 34 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +ZNF518B UCSF GRCh37 4 10445063 10445063 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Pri_D Untested WXS Illumina HiSeq 226 35 233 0 ENST00000326756.3:c.2890A>T p.Asn964Tyr p.N964Y ENST00000326756 NM_053042.2 964 Aat/Tat 0 +A1BG UCSF GRCh37 19 58862971 58862971 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 25 60 0 ENST00000263100.3:c.696C>T p.Cys232= p.C232= ENST00000263100 NM_130786.3 232 tgC/tgT 0 +A2M UCSF GRCh37 12 9229956 9229956 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 24 16 51 0 ENST00000318602.7:c.3337C>T p.Pro1113Ser p.P1113S ENST00000318602 NM_000014.4 1113 Cct/Tct 0 +AADACL4 UCSF GRCh37 1 12721866 12721866 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 81 158 0 ENST00000376221.1:c.449+1G>A p.X150_splice ENST00000376221 NM_001013630.1 0 +AARS UCSF GRCh37 16 70287616 70287616 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 35 35 75 0 ENST00000261772.8:c.2607+1G>A p.X869_splice ENST00000261772 NM_001605.2 0 +AARS2 UCSF GRCh37 6 44271120 44271120 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 44 65 0 ENST00000244571.4:c.2048C>T p.Thr683Ile p.T683I ENST00000244571 NM_020745.3 683 aCt/aTt 0 +AARSD1 UCSF GRCh37 17 41107981 41107981 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 88 192 0 ENST00000421990.2:c.1194G>A p.Lys398= p.K398= ENST00000421990 NM_001136042.2 398 aaG/aaA 0 +AASDH UCSF GRCh37 4 57204898 57204898 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 64 135 0 ENST00000205214.6:c.2967G>A p.Glu989= p.E989= ENST00000205214 NM_181806.2 989 gaG/gaA 0 +AATK UCSF GRCh37 17 79094371 79094371 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 7 17 0 ENST00000326724.4:c.3365G>A p.Gly1122Glu p.G1122E ENST00000326724 NM_001080395.2 1122 gGa/gAa 0 +ABCA1 UCSF GRCh37 9 107547874 107547874 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 81 171 0 ENST00000374736.3:c.6448C>T p.Pro2150Ser p.P2150S ENST00000374736 NM_005502.3 2150 Ccg/Tcg 0 +ABCA1 UCSF GRCh37 9 107549232 107549232 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 75 177 0 ENST00000374736.3:c.6230C>T p.Pro2077Leu p.P2077L ENST00000374736 NM_005502.3 2077 cCc/cTc 0 +ABCA12 UCSF GRCh37 2 215917211 215917211 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 49 105 0 ENST00000272895.7:c.507G>A p.Lys169= p.K169= ENST00000272895 NM_173076.2 169 aaG/aaA 0 +ABCA13 UCSF GRCh37 7 48391970 48391970 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P18_Rec Untested WXS Illumina HiSeq 64 0 ENST00000435803.1:c.10577del p.Pro3526HisfsTer5 p.P3526Hfs*5 ENST00000435803 NM_152701.3 3525 gCc/gc 0 +ABCA2 UCSF GRCh37 9 139910874 139910874 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 54 124 0 ENST00000341511.6:c.2973C>T p.Val991= p.V991= ENST00000341511 NM_212533.2 991 gtC/gtT 0 +ABCA2 UCSF GRCh37 9 139902948 139902948 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 7 10 0 ENST00000341511.6:c.7195G>A p.Glu2399Lys p.E2399K ENST00000341511 NM_212533.2 2399 Gag/Aag 0 +ABCA3 UCSF GRCh37 16 2374452 2374452 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 12 35 0 ENST00000301732.5:c.400G>A p.Val134Ile p.V134I ENST00000301732 NM_001089.2 134 Gtc/Atc 0 +ABCA3 UCSF GRCh37 16 2336836 2336836 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 59 117 0 ENST00000301732.5:c.3137C>T p.Ala1046Val p.A1046V ENST00000301732 NM_001089.2 1046 gCg/gTg 0 +ABCA3 UCSF GRCh37 16 2334326 2334326 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 140 46 75 0 ENST00000301732.5:c.3816G>A p.Arg1272= p.R1272= ENST00000301732 NM_001089.2 1272 agG/agA 0 +ABCA4 UCSF GRCh37 1 94544147 94544147 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 64 140 0 ENST00000370225.3:c.1355G>A p.Arg452Lys p.R452K ENST00000370225 NM_000350.2 452 aGa/aAa 0 +ABCA5 UCSF GRCh37 17 67309286 67309286 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 63 179 0 ENST00000392676.3:c.254C>A p.Thr85Asn p.T85N ENST00000392676 85 aCt/aAt 0 +ABCA6 UCSF GRCh37 17 67103919 67103919 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 67 125 0 ENST00000284425.2:c.2307G>A p.Gln769= p.Q769= ENST00000284425 NM_080284.2 769 caG/caA 0 +ABCB1 UCSF GRCh37 7 87175303 87175303 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 94 217 0 ENST00000265724.3:c.1763G>A p.Arg588His p.R588H ENST00000265724 NM_000927.4 588 cGt/cAt 0 +ABCB9 UCSF GRCh37 12 123419954 123419954 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 40 73 0 ENST00000542678.1:c.1768G>A p.Val590Met p.V590M ENST00000542678 590 Gtg/Atg 0 +ABCC10 UCSF GRCh37 6 43400588 43400588 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 45 94 0 ENST00000372530.4:c.870G>A p.Leu290= p.L290= ENST00000372530 NM_001198934.1 290 ctG/ctA 0 +ABL1 UCSF GRCh37 9 133760187 133760187 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 21 46 0 ENST00000318560.5:c.2510G>A p.Gly837Glu p.G837E ENST00000318560 NM_005157.4 837 gGa/gAa 0 +ABLIM3 UCSF GRCh37 5 148620338 148620338 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 65 124 0 ENST00000506113.1:c.1303+1G>A p.X435_splice ENST00000506113 0 +ABTB2 UCSF GRCh37 11 34184228 34184228 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 28 53 0 ENST00000435224.2:c.2113G>A p.Gly705Arg p.G705R ENST00000435224 NM_145804.2 705 Ggg/Agg 0 +ACAA2 UCSF GRCh37 18 47311620 47311620 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 67 131 0 ENST00000285093.10:c.1056C>T p.His352= p.H352= ENST00000285093 NM_006111.2 352 caC/caT 0 +ACACA UCSF GRCh37 17 35545383 35545383 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 53 116 0 ENST00000353139.5:c.4610G>A p.Gly1537Glu p.G1537E ENST00000353139 NM_198834.1 1537 gGa/gAa 0 +ACACA UCSF GRCh37 17 35603853 35603853 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 164 88 210 0 ENST00000353139.5:c.2349G>A p.Glu783= p.E783= ENST00000353139 NM_198834.1 783 gaG/gaA 0 +ACAD10 UCSF GRCh37 12 112186993 112186993 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 166 111 268 0 ENST00000455480.2:c.2754C>T p.Val918= p.V918= ENST00000455480 NM_001136538.1 918 gtC/gtT 0 +ACAD9 UCSF GRCh37 3 128612436 128612436 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 42 103 0 ENST00000308982.7:c.283G>A p.Asp95Asn p.D95N ENST00000308982 NM_014049.4 95 Gat/Aat 0 +ACADVL UCSF GRCh37 17 7128190 7128190 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 39 84 0 ENST00000543245.2:c.1883C>T p.Thr628Ile p.T628I ENST00000543245 NM_001270447.1 628 aCc/aTc 0 +ACAN UCSF GRCh37 15 89398830 89398830 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 65 231 0 ENST00000439576.2:c.3014C>T p.Ala1005Val p.A1005V ENST00000439576 NM_013227.3 1005 gCc/gTc 0 +ACAN UCSF GRCh37 15 89400170 89400170 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 237 147 365 0 ENST00000439576.2:c.4354C>T p.Pro1452Ser p.P1452S ENST00000439576 NM_013227.3 1452 Cct/Tct 0 +ACAN UCSF GRCh37 15 89417131 89417131 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 39 92 0 ENST00000439576.2:c.7392C>T p.Asp2464= p.D2464= ENST00000439576 NM_013227.3 2464 gaC/gaT 0 +ACAN UCSF GRCh37 15 89415235 89415235 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 98 182 0 ENST00000439576.2:c.7107C>T p.Asn2369= p.N2369= ENST00000439576 NM_013227.3 2369 aaC/aaT 0 +ACHE UCSF GRCh37 7 100490427 100490427 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 8 20 0 ENST00000302913.4:c.1081G>A p.Val361Met p.V361M ENST00000302913 NM_015831.2 361 Gtg/Atg 0 +ACO1 UCSF GRCh37 9 32427404 32427404 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 25 85 207 0 ENST00000309951.6:c.1454G>A p.Ser485Asn p.S485N ENST00000309951 NM_002197.2 485 aGc/aAc 0 +ACOT12 UCSF GRCh37 5 80626249 80626249 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 65 187 0 ENST00000307624.3:c.1632G>A p.Glu544= p.E544= ENST00000307624 NM_130767.2 544 gaG/gaA 0 +ACOT4 UCSF GRCh37 14 74061941 74061941 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 70 201 0 ENST00000326303.4:c.849G>A p.Lys283= p.K283= ENST00000326303 NM_152331.3 283 aaG/aaA 0 +ACOX2 UCSF GRCh37 3 58520818 58520818 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 143 111 259 0 ENST00000302819.5:c.16C>T p.His6Tyr p.H6Y ENST00000302819 NM_003500.3 6 Cac/Tac 0 +ACOX2 UCSF GRCh37 3 58510152 58510152 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 45 114 0 ENST00000302819.5:c.1526+1G>A p.X509_splice ENST00000302819 NM_003500.3 0 +ACOXL UCSF GRCh37 2 111551752 111551752 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 38 63 0 ENST00000439055.1:c.345+1G>A p.X115_splice ENST00000439055 NM_001142807.1 0 +ACP5 UCSF GRCh37 19 11688112 11688112 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 21 44 0 ENST00000592828.1:c.21G>A p.Leu7= p.L7= ENST00000592828 NM_001111034.1 7 ctG/ctA 0 +ACP6 UCSF GRCh37 1 147122026 147122026 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 47 41 76 0 ENST00000369238.6:c.897G>A p.Met299Ile p.M299I ENST00000369238 NM_016361.4 299 atG/atA 0 +ACP6 UCSF GRCh37 1 147131086 147131086 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 99 221 0 ENST00000369238.6:c.548G>A p.Cys183Tyr p.C183Y ENST00000369238 NM_016361.4 183 tGt/tAt 0 +ACP6 UCSF GRCh37 1 147131860 147131860 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 47 108 0 ENST00000369238.6:c.250C>T p.Pro84Ser p.P84S ENST00000369238 NM_016361.4 84 Cca/Tca 0 +ACPP UCSF GRCh37 3 132068815 132068815 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 72 150 0 ENST00000351273.7:c.833C>T p.Pro278Leu p.P278L ENST00000351273 NM_001134194.1 278 cCa/cTa 0 +ACSBG2 UCSF GRCh37 19 6151774 6151774 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 14 22 0 ENST00000586696.1:c.354G>A p.Trp118Ter p.W118* ENST00000586696 118 tgG/tgA 0 +ACTG1 UCSF GRCh37 17 79477785 79477785 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 75 177 0 ENST00000575842.1:c.1059G>A p.Gln353= p.Q353= ENST00000575842 353 caG/caA 0 +ACTN1 UCSF GRCh37 14 69343938 69343938 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 47 133 0 ENST00000394419.4:c.2447G>A p.Arg816His p.R816H ENST00000394419 NM_001130004.1 816 cGc/cAc 0 +ACTN1 UCSF GRCh37 14 69347572 69347572 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 86 196 0 ENST00000394419.4:c.2088G>A p.Gln696= p.Q696= ENST00000394419 NM_001130004.1 696 caG/caA 0 +ACTR5 UCSF GRCh37 20 37396227 37396227 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 95 187 0 ENST00000243903.4:c.1554G>A p.Arg518= p.R518= ENST00000243903 NM_024855.3 518 cgG/cgA 0 +ADAM10 UCSF GRCh37 15 58938330 58938330 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P18_Rec Untested WXS Illumina HiSeq 8 0 ENST00000260408.3:c.659del p.Asn220IlefsTer23 p.N220Ifs*23 ENST00000260408 NM_001110.2 220 aAt/at 0 +ADAM15 UCSF GRCh37 1 155028467 155028467 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 38 103 0 ENST00000356955.2:c.735G>A p.Leu245= p.L245= ENST00000356955 NM_207197.2 245 ttG/ttA 0 +ADAM2 UCSF GRCh37 8 39624683 39624683 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 163 111 225 0 ENST00000265708.4:c.1300G>A p.Glu434Lys p.E434K ENST00000265708 NM_001464.4 434 Gaa/Aaa 0 +ADAM8 UCSF GRCh37 10 135085974 135085974 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 36 17 48 0 ENST00000445355.3:c.821G>A p.Trp274Ter p.W274* ENST00000445355 NM_001109.4 274 tGg/tAg 0 +ADAMTS13 UCSF GRCh37 9 136320640 136320640 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 30 81 0 ENST00000371929.3:c.3483G>A p.Trp1161Ter p.W1161* ENST00000371929 NM_139025.4 1161 tgG/tgA 0 +ADAMTS13 UCSF GRCh37 9 136303014 136303014 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 36 95 0 ENST00000371929.3:c.1581C>T p.Cys527= p.C527= ENST00000371929 NM_139025.4 527 tgC/tgT 0 +ADAMTS13 UCSF GRCh37 9 136313814 136313814 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 24 62 0 ENST00000371929.3:c.2826G>A p.Arg942= p.R942= ENST00000371929 NM_139025.4 942 cgG/cgA 0 +ADAMTS15 UCSF GRCh37 11 130319744 130319744 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 50 121 0 ENST00000299164.2:c.876C>T p.Phe292= p.F292= ENST00000299164 NM_139055.2 292 ttC/ttT 0 +ADAMTS4 UCSF GRCh37 1 161166346 161166346 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 34 117 0 ENST00000367996.5:c.957+1G>A p.X319_splice ENST00000367996 NM_005099.4 0 +ADAMTS9 UCSF GRCh37 3 64607929 64607929 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 63 127 0 ENST00000498707.1:c.2631G>A p.Gln877= p.Q877= ENST00000498707 NM_182920.1 877 caG/caA 0 +ADAMTSL4 UCSF GRCh37 1 150531823 150531823 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 56 115 0 ENST00000271643.4:c.2824G>A p.Gly942Arg p.G942R ENST00000271643 NM_019032.4 942 Ggg/Agg 0 +ADCK5 UCSF GRCh37 8 145618060 145618060 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 12 0 ENST00000308860.6:c.1590C>T p.Arg530= p.R530= ENST00000308860 NM_174922.4 530 cgC/cgT 0 +ADCY10 UCSF GRCh37 1 167847697 167847697 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 110 92 176 0 ENST00000367851.4:c.1393C>G p.Arg465Gly p.R465G ENST00000367851 NM_018417.4 465 Cgt/Ggt 0 +ADCY9 UCSF GRCh37 16 4015884 4015884 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 185 72 200 0 ENST00000294016.3:c.3954C>T p.Ala1318= p.A1318= ENST00000294016 NM_001116.3 1318 gcC/gcT 0 +ADCY9 UCSF GRCh37 16 4163830 4163830 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 265 99 244 0 ENST00000294016.3:c.1614C>T p.Tyr538= p.Y538= ENST00000294016 NM_001116.3 538 taC/taT 0 +ADH5 UCSF GRCh37 4 100006287 100006287 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 171 130 246 0 ENST00000296412.8:c.93G>A p.Lys31= p.K31= ENST00000296412 NM_000671.3 31 aaG/aaA 0 +ADORA3 UCSF GRCh37 1 112042978 112042978 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 203 148 309 0 ENST00000369716.4:c.350+2649C>T *117* ENST00000369716 NM_020683.6 0 +ADRB3 UCSF GRCh37 8 37823551 37823551 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 15 0 ENST00000345060.3:c.437G>A p.Gly146Asp p.G146D ENST00000345060 NM_000025.2 146 gGc/gAc 0 +ADRBK2 UCSF GRCh37 22 26110537 26110537 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 51 99 0 ENST00000324198.6:c.1654G>A p.Asp552Asn p.D552N ENST00000324198 NM_005160.3 552 Gat/Aat 0 +ADSL UCSF GRCh37 22 40749101 40749101 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 74 56 116 0 ENST00000216194.7:c.382C>T p.Leu128Phe p.L128F ENST00000216194 NM_000026.2 128 Ctt/Ttt 0 +AFF2 UCSF GRCh37 X 148037697 148037697 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 123 104 0 ENST00000370460.2:c.2122C>T p.Arg708Trp p.R708W ENST00000370460 NM_002025.3 708 Cgg/Tgg 0 +AFF4 UCSF GRCh37 5 132238158 132238158 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 34 90 0 ENST00000265343.5:c.1109C>T p.Thr370Ile p.T370I ENST00000265343 NM_014423.3 370 aCt/aTt 0 +AGA UCSF GRCh37 4 178357482 178357482 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 51 142 0 ENST00000264595.2:c.646G>A p.Gly216Arg p.G216R ENST00000264595 NM_001171988.1 216 Gga/Aga 0 +AGAP1 UCSF GRCh37 2 237029007 237029007 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 46 121 0 ENST00000304032.8:c.2286G>A p.Glu762= p.E762= ENST00000304032 NM_001037131.2 762 gaG/gaA 0 +AGAP5 UCSF GRCh37 10 75434558 75434558 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 66 285 0 ENST00000374094.4:c.1860G>A p.Gly620= p.G620= ENST00000374094 NM_001144000.1 620 ggG/ggA 0 +AGBL1 UCSF GRCh37 15 86790901 86790901 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 34 16 76 0 ENST00000441037.2:c.389-1G>A p.X130_splice ENST00000441037 NM_152336.2 0 +AGBL3 UCSF GRCh37 7 134674001 134674001 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 34 63 0 ENST00000436302.2:c.64G>A p.Asp22Asn p.D22N ENST00000436302 NM_178563.3 22 Gat/Aat 0 +AGBL5 UCSF GRCh37 2 27282331 27282331 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 69 151 0 ENST00000360131.4:c.2089+59G>A *697* ENST00000360131 NM_021831.5 0 +AGRP UCSF GRCh37 16 67516602 67516602 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 73 64 112 0 ENST00000290953.2:c.336C>T p.Phe112= p.F112= ENST00000290953 NM_001138.1 112 ttC/ttT 0 +AHCY UCSF GRCh37 20 32880197 32880197 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 37 88 0 ENST00000217426.2:c.412C>T p.Leu138Phe p.L138F ENST00000217426 NM_000687.2 138 Ctc/Ttc 0 +AHI1 UCSF GRCh37 6 135732643 135732643 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 162 116 240 0 ENST00000367800.4:c.2804G>A p.Gly935Glu p.G935E ENST00000367800 NM_001134830.1 935 gGa/gAa 0 +AHI1 UCSF GRCh37 6 135787067 135787067 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 164 325 0 ENST00000367800.4:c.634C>T p.Leu212= p.L212= ENST00000367800 NM_001134830.1 212 Ctg/Ttg 0 +AHNAK UCSF GRCh37 11 62284334 62284334 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 121 254 0 ENST00000378024.4:c.17555G>A p.Gly5852Glu p.G5852E ENST00000378024 NM_001620.2 5852 gGg/gAg 0 +AHNAK UCSF GRCh37 11 62294198 62294198 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 205 180 305 0 ENST00000378024.4:c.7691G>A p.Gly2564Glu p.G2564E ENST00000378024 NM_001620.2 2564 gGg/gAg 0 +AIM2 UCSF GRCh37 1 159036085 159036085 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 70 197 0 ENST00000368130.4:c.431C>T p.Ser144Phe p.S144F ENST00000368130 NM_004833.1 144 tCt/tTt 0 +AKAP11 UCSF GRCh37 13 42874392 42874392 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 110 66 188 0 ENST00000025301.2:c.1510C>T p.Leu504Phe p.L504F ENST00000025301 NM_016248.3 504 Ctt/Ttt 0 +AKAP2 UCSF GRCh37 9 112899087 112899087 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 67 129 0 ENST00000374530.3:c.1263C>T p.Pro421= p.P421= ENST00000374530 NM_007203.4 421 ccC/ccT 0 +AKAP3 UCSF GRCh37 12 4736817 4736817 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 172 129 258 0 ENST00000545990.2:c.1251C>T p.Asn417= p.N417= ENST00000545990 NM_001278309.1 417 aaC/aaT 0 +AKAP8L UCSF GRCh37 19 15512246 15512246 + synonymous_variant Silent SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 34 89 0 ENST00000397410.5:c.531T>A p.Gly177= p.G177= ENST00000397410 NM_014371.2 177 ggT/ggA 0 +AKR1C1 UCSF GRCh37 10 5008159 5008159 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 269 102 207 0 ENST00000380872.4:c.138C>T p.Phe46= p.F46= ENST00000380872 NM_001353.5 46 ttC/ttT 0 +AKR1E2 UCSF GRCh37 10 4872956 4872956 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 199 76 178 0 ENST00000298375.7:c.129G>A p.Glu43= p.E43= ENST00000298375 NM_001040177.2 43 gaG/gaA 0 +AKTIP UCSF GRCh37 16 53532381 53532381 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 117 278 0 ENST00000394657.7:c.170C>T p.Ala57Val p.A57V ENST00000394657 NM_022476.2 57 gCc/gTc 0 +ALDH1L1 UCSF GRCh37 3 125826076 125826076 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 77 172 0 ENST00000273450.3:c.2391G>A p.Glu797= p.E797= ENST00000273450 NM_001270364.1 797 gaG/gaA 0 +ALDH3B1 UCSF GRCh37 11 67790074 67790074 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 41 70 0 ENST00000539229.1:c.955C>T p.Leu319= p.L319= ENST00000539229 NM_001161473.1 319 Ctg/Ttg 0 +ALDH3B2 UCSF GRCh37 11 67433865 67433865 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 13 17 0 ENST00000349015.3:c.159C>T p.Cys53= p.C53= ENST00000349015 NM_000695.3 53 tgC/tgT 0 +ALDH6A1 UCSF GRCh37 14 74533452 74533452 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 91 201 0 ENST00000553458.1:c.1180G>A p.Glu394Lys p.E394K ENST00000553458 NM_001278593.1 394 Gaa/Aaa 0 +ALG9 UCSF GRCh37 11 111708288 111708288 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 58 146 0 ENST00000531154.1:c.862G>A p.Asp288Asn p.D288N ENST00000531154 NM_024740.2 288 Gac/Aac 0 +ALKBH5 UCSF GRCh37 17 18110225 18110225 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 196 125 261 0 ENST00000399138.4:c.948G>A p.Arg316= p.R316= ENST00000399138 NM_017758.3 316 agG/agA 0 +ALMS1 UCSF GRCh37 2 73678109 73678109 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 165 137 267 0 ENST00000264448.6:c.4452C>T p.Ile1484= p.I1484= ENST00000264448 NM_015120.4 1484 atC/atT 0 +ALOX12B UCSF GRCh37 17 7977054 7977054 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 24 64 0 ENST00000319144.4:c.1676C>T p.Thr559Ile p.T559I ENST00000319144 NM_001139.2 559 aCc/aTc 0 +ALPL UCSF GRCh37 1 21890579 21890579 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 30 72 0 ENST00000374840.3:c.518C>T p.Thr173Ile p.T173I ENST00000374840 NM_000478.4 173 aCc/aTc 0 +ALPPL2 UCSF GRCh37 2 233274457 233274457 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 17 22 0 ENST00000295453.3:c.1474G>A p.Ala492Thr p.A492T ENST00000295453 NM_031313.2 492 Gcc/Acc 0 +ALS2CL UCSF GRCh37 3 46729143 46729143 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 22 46 0 ENST00000318962.4:c.334G>A p.Val112Met p.V112M ENST00000318962 NM_147129.3 112 Gtg/Atg 0 +ALS2CL UCSF GRCh37 3 46713075 46713075 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 39 88 0 ENST00000318962.4:c.2685-1G>A p.X895_splice ENST00000318962 NM_147129.3 0 +AMBRA1 UCSF GRCh37 11 46430176 46430176 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 38 73 0 ENST00000314845.3:c.3020C>T p.Thr1007Ile p.T1007I ENST00000314845 NM_017749.3 1007 aCc/aTc 0 +AMPD2 UCSF GRCh37 1 110173373 110173373 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 20 0 ENST00000256578.3:c.2388G>A p.Glu796= p.E796= ENST00000256578 NM_004037.7 796 gaG/gaA 0 +AMPH UCSF GRCh37 7 38534069 38534069 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 97 183 0 ENST00000356264.2:c.264C>T p.Asp88= p.D88= ENST00000356264 NM_001635.3 88 gaC/gaT 0 +AMT UCSF GRCh37 3 49455068 49455068 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 85 169 0 ENST00000273588.3:c.1117G>A p.Gly373Arg p.G373R ENST00000273588 NM_000481.3 373 Ggg/Agg 0 +AMY2A UCSF GRCh37 1 104160104 104160104 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 412 106 634 0 ENST00000414303.2:c.42G>A p.Trp14Ter p.W14* ENST00000414303 NM_000699.2 14 tgG/tgA 0 +ANK2 UCSF GRCh37 4 114276282 114276282 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 79 154 0 ENST00000357077.4:c.6508C>T p.Leu2170Phe p.L2170F ENST00000357077 NM_001148.4 2170 Ctc/Ttc 0 +ANK3 UCSF GRCh37 10 61898737 61898737 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 135 103 184 0 ENST00000280772.2:c.2723G>A p.Gly908Glu p.G908E ENST00000280772 NM_020987.3 908 gGa/gAa 0 +ANK3 UCSF GRCh37 10 61835701 61835701 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 66 154 0 ENST00000280772.2:c.4938C>T p.Ser1646= p.S1646= ENST00000280772 NM_020987.3 1646 tcC/tcT 0 +ANKDD1A UCSF GRCh37 15 65208096 65208096 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 30 63 0 ENST00000380230.3:c.135C>T p.Asn45= p.N45= ENST00000380230 NM_182703.3 45 aaC/aaT 0 +ANKRA2 UCSF GRCh37 5 72858513 72858513 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 184 147 257 0 ENST00000296785.3:c.194G>A p.Cys65Tyr p.C65Y ENST00000296785 NM_023039.4 65 tGt/tAt 0 +ANKRD11 UCSF GRCh37 16 89371633 89371633 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 35 64 0 ENST00000301030.4:c.207G>A p.Glu69= p.E69= ENST00000301030 NM_001256183.1 69 gaG/gaA 0 +ANKRD13B UCSF GRCh37 17 27939242 27939242 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 66 165 0 ENST00000394859.3:c.1209C>T p.Leu403= p.L403= ENST00000394859 NM_152345.4 403 ctC/ctT 0 +ANKRD13C UCSF GRCh37 1 70819858 70819858 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 60 134 0 ENST00000370944.4:c.234G>A p.Leu78= p.L78= ENST00000370944 NM_030816.4 78 ctG/ctA 0 +ANKRD13C UCSF GRCh37 1 70736609 70736609 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 34 102 0 ENST00000370944.4:c.1425C>T p.Pro475= p.P475= ENST00000370944 NM_030816.4 475 ccC/ccT 0 +ANKRD17 UCSF GRCh37 4 73957296 73957296 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 202 148 352 0 ENST00000358602.4:c.6049G>A p.Ala2017Thr p.A2017T ENST00000358602 NM_032217.3 2017 Gca/Aca 0 +ANKRD17 UCSF GRCh37 4 74017241 74017241 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 41 127 0 ENST00000358602.4:c.1235G>A p.Gly412Glu p.G412E ENST00000358602 NM_032217.3 412 gGa/gAa 0 +ANKRD2 UCSF GRCh37 10 99342361 99342361 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 66 168 0 ENST00000307518.5:c.835G>A p.Glu279Lys p.E279K ENST00000307518 279 Gaa/Aaa 0 +ANKRD20A4 UCSF GRCh37 9 69423583 69423583 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 444 83 953 0 ENST00000357336.3:c.1879G>A p.Glu627Lys p.E627K ENST00000357336 NM_001098805.1 627 Gaa/Aaa 0 +ANKRD36 UCSF GRCh37 2 97909671 97909671 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 156 93 300 0 ENST00000420699.2:c.4474C>T p.Gln1492Ter p.Q1492* ENST00000420699 NM_001164315.1 1492 Caa/Taa 0 +ANKRD57 UCSF GRCh37 2 110373562 110373562 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 49 108 0 ENST00000356454.3:c.1496G>A p.Gly499Glu p.G499E ENST00000356454 NM_023016.3 499 gGg/gAg 0 +ANKZF1 UCSF GRCh37 2 220095054 220095054 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 40 72 0 ENST00000323348.5:c.75C>T p.Val25= p.V25= ENST00000323348 NM_018089.2 25 gtC/gtT 0 +ANO10 UCSF GRCh37 3 43602826 43602826 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 80 213 0 ENST00000292246.3:c.1362G>A p.Trp454Ter p.W454* ENST00000292246 NM_018075.3 454 tgG/tgA 0 +ANO3 UCSF GRCh37 11 26484612 26484612 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 69 155 0 ENST00000256737.3:c.349G>A p.Glu117Lys p.E117K ENST00000256737 NM_031418.2 117 Gaa/Aaa 0 +ANO3 UCSF GRCh37 11 26664788 26664788 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 89 189 0 ENST00000256737.3:c.2335G>A p.Ala779Thr p.A779T ENST00000256737 NM_031418.2 779 Gct/Act 0 +ANXA7 UCSF GRCh37 10 75158082 75158082 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 34 79 0 ENST00000372919.4:c.116C>T p.Pro39Leu p.P39L ENST00000372919 NM_004034.2 39 cCt/cTt 0 +AOC3 UCSF GRCh37 17 41006484 41006484 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 44 33 74 0 ENST00000308423.2:c.1620G>A p.Trp540Ter p.W540* ENST00000308423 NM_003734.3 540 tgG/tgA 0 +AP1M1 UCSF GRCh37 19 16339647 16339647 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 41 86 0 ENST00000444449.2:c.991G>A p.Asp331Asn p.D331N ENST00000444449 NM_001130524.1 331 Gat/Aat 0 +AP3D1 UCSF GRCh37 19 2114812 2114812 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 40 108 0 ENST00000355272.6:c.2358G>A p.Leu786= p.L786= ENST00000355272 NM_001261826.1 786 ctG/ctA 0 +AP3M2 UCSF GRCh37 8 42025183 42025183 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 91 224 0 ENST00000518421.1:c.1012-1G>A p.X338_splice ENST00000518421 NM_001134296.1 0 +APBB1IP UCSF GRCh37 10 26856330 26856330 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 17 52 0 ENST00000376236.4:c.1914G>A p.Gly638= p.G638= ENST00000376236 NM_019043.3 638 ggG/ggA 0 +APBB3 UCSF GRCh37 5 139942017 139942017 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 119 256 0 ENST00000354402.5:c.419G>A p.Ser140Asn p.S140N ENST00000354402 140 aGt/aAt 0 +APC UCSF GRCh37 5 112177881 112177881 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 76 219 0 ENST00000257430.4:c.6590G>A p.Ser2197Asn p.S2197N ENST00000257430 NM_000038.5 2197 aGt/aAt 0 +APLP1 UCSF GRCh37 19 36362177 36362177 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 13 28 0 ENST00000221891.4:c.463G>A p.Gly155Ser p.G155S ENST00000221891 NM_001024807.1 155 Ggc/Agc 0 +APOA4 UCSF GRCh37 11 116692033 116692033 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 72 170 0 ENST00000357780.3:c.741G>A p.Lys247= p.K247= ENST00000357780 NM_000482.3 247 aaG/aaA 0 +APPBP2 UCSF GRCh37 17 58571898 58571898 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 128 93 180 0 ENST00000083182.3:c.308G>A p.Arg103Lys p.R103K ENST00000083182 NM_006380.2 103 aGg/aAg 0 +AQP12B UCSF GRCh37 2 241621893 241621893 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 25 61 0 ENST00000407834.3:c.362G>A p.Gly121Asp p.G121D ENST00000407834 NM_001102467.1 121 gGc/gAc 0 +AQPEP UCSF GRCh37 5 115298720 115298720 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 36 68 0 ENST00000357872.4:c.406C>T p.Arg136Cys p.R136C ENST00000357872 NM_173800.4 136 Cgc/Tgc 0 +ARAP2 UCSF GRCh37 4 36212219 36212219 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 160 104 270 0 ENST00000303965.4:c.1280G>A p.Arg427Lys p.R427K ENST00000303965 NM_015230.3 427 aGa/aAa 0 +ARAP2 UCSF GRCh37 4 36149369 36149369 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 30 65 0 ENST00000303965.4:c.3001-1G>A p.X1001_splice ENST00000303965 NM_015230.3 0 +ARFGEF2 UCSF GRCh37 20 47601368 47601368 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 134 88 187 0 ENST00000371917.4:c.2061C>T p.Arg687= p.R687= ENST00000371917 NM_006420.2 687 cgC/cgT 0 +ARG1 UCSF GRCh37 6 131904993 131904993 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 76 159 0 ENST00000356962.2:c.938G>A p.Gly313Glu p.G313E ENST00000356962 NM_001244438.1 313 gGa/gAa 0 +ARHGAP12 UCSF GRCh37 10 32120720 32120720 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 199 66 116 1 ENST00000344936.2:c.1395G>A p.Glu465= p.E465= ENST00000344936 NM_001270697.1 465 gaG/gaA 0 +ARHGAP17 UCSF GRCh37 16 24946897 24946897 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 31 59 0 ENST00000289968.6:c.1788G>A p.Gln596= p.Q596= ENST00000289968 NM_001006634.1 596 caG/caA 0 +ARHGAP21 UCSF GRCh37 10 24885691 24885691 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 211 74 166 0 ENST00000396432.2:c.3455G>A p.Cys1152Tyr p.C1152Y ENST00000396432 NM_020824.3 1152 tGc/tAc 0 +ARHGAP21 UCSF GRCh37 10 24922386 24922386 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 47 115 0 ENST00000396432.2:c.385G>A p.Gly129Arg p.G129R ENST00000396432 NM_020824.3 129 Gga/Aga 0 +ARHGAP24 UCSF GRCh37 4 86915904 86915904 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 183 158 302 0 ENST00000395184.1:c.1097C>T p.Thr366Ile p.T366I ENST00000395184 NM_001025616.2 366 aCc/aTc 0 +ARHGAP29 UCSF GRCh37 1 94643491 94643491 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 100 189 0 ENST00000260526.6:c.2713G>A p.Gly905Ser p.G905S ENST00000260526 NM_004815.3 905 Ggc/Agc 0 +ARHGAP29 UCSF GRCh37 1 94650550 94650550 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 32 79 0 ENST00000260526.6:c.1987C>T p.Pro663Ser p.P663S ENST00000260526 NM_004815.3 663 Cca/Tca 0 +ARHGAP29 UCSF GRCh37 1 94655595 94655595 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 55 109 0 ENST00000260526.6:c.1326C>T p.Ser442= p.S442= ENST00000260526 NM_004815.3 442 tcC/tcT 0 +ARHGAP35 UCSF GRCh37 19 47422027 47422027 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 175 149 251 0 ENST00000404338.3:c.95G>A p.Gly32Glu p.G32E ENST00000404338 NM_004491.4 32 gGg/gAg 0 +ARHGAP35 UCSF GRCh37 19 47423996 47423996 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 87 184 0 ENST00000404338.3:c.2064G>A p.Arg688= p.R688= ENST00000404338 NM_004491.4 688 cgG/cgA 0 +ARHGAP39 UCSF GRCh37 8 145759561 145759561 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 35 111 0 ENST00000377307.2:c.2640G>A p.Lys880= p.K880= ENST00000377307 NM_025251.1 880 aaG/aaA 0 +ARHGAP9 UCSF GRCh37 12 57869182 57869182 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 3 11 19 0 ENST00000393791.3:c.1445-1G>A p.X482_splice ENST00000393791 NM_032496.2 0 +ARHGAP9 UCSF GRCh37 12 57872322 57872322 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 75 137 0 ENST00000393791.3:c.534+1G>A p.X178_splice ENST00000393791 NM_032496.2 0 +ARHGEF17 UCSF GRCh37 11 73022664 73022664 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 65 129 0 ENST00000263674.3:c.2981C>T p.Ala994Val p.A994V ENST00000263674 NM_014786.3 994 gCc/gTc 0 +ARHGEF17 UCSF GRCh37 11 73076881 73076881 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 40 104 0 ENST00000263674.3:c.5884C>T p.Pro1962Ser p.P1962S ENST00000263674 NM_014786.3 1962 Ccc/Tcc 0 +ARID1A UCSF GRCh37 1 27101587 27101587 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 88 173 0 ENST00000324856.7:c.4869G>A p.Ser1623= p.S1623= ENST00000324856 NM_006015.4 1623 tcG/tcA 0 +ARL4D UCSF GRCh37 17 41477501 41477501 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 15 46 0 ENST00000320033.4:c.401C>T p.Ala134Val p.A134V ENST00000320033 NM_001661.3 134 gCc/gTc 0 +ARMC8 UCSF GRCh37 3 137956329 137956329 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 59 147 0 ENST00000481646.1:c.649G>A p.Val217Ile p.V217I ENST00000481646 NM_015396.4 217 Gtt/Att 0 +ARNTL2 UCSF GRCh37 12 27554297 27554297 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 80 171 0 ENST00000266503.5:c.1267+1G>A p.X423_splice ENST00000266503 0 +ARSI UCSF GRCh37 5 149678062 149678062 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 47 70 0 ENST00000328668.7:c.425C>T p.Thr142Ile p.T142I ENST00000328668 NM_001012301.2 142 aCc/aTc 0 +ASB14 UCSF GRCh37 3 57322030 57322030 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P18_Rec Untested WXS Illumina HiSeq 6 0 ENST00000487349.1:c.368del p.Leu123TrpfsTer8 p.L123Wfs*8 ENST00000487349 NM_001142733.2 123 tTg/tg 0 +ASB14 UCSF GRCh37 3 57317424 57317424 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 64 141 0 ENST00000487349.1:c.513C>T p.Asn171= p.N171= ENST00000487349 NM_001142733.2 171 aaC/aaT 0 +ASCL4 UCSF GRCh37 12 108169329 108169329 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 8 17 0 ENST00000342331.4:c.337G>A p.Glu113Lys p.E113K ENST00000342331 NM_203436.2 113 Gag/Aag 0 +ASH1L UCSF GRCh37 1 155449560 155449560 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 109 198 0 ENST00000392403.3:c.3101G>A p.Gly1034Asp p.G1034D ENST00000392403 NM_018489.2 1034 gGc/gAc 0 +ASH1L UCSF GRCh37 1 155451426 155451426 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 89 220 0 ENST00000392403.3:c.1235C>T p.Pro412Leu p.P412L ENST00000392403 NM_018489.2 412 cCt/cTt 0 +ASTN2 UCSF GRCh37 9 119568068 119568068 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 113 266 0 ENST00000361209.2:c.2086G>A p.Gly696Arg p.G696R ENST00000361209 NM_014010.4 696 Gga/Aga 0 +ASTN2 UCSF GRCh37 9 120053656 120053656 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 37 88 0 ENST00000361209.2:c.579G>A p.Glu193= p.E193= ENST00000361209 NM_014010.4 193 gaG/gaA 0 +ASXL3 UCSF GRCh37 18 31326351 31326351 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 151 108 207 0 ENST00000269197.5:c.6539G>A p.Ser2180Asn p.S2180N ENST00000269197 NM_030632.1 2180 aGt/aAt 0 +ATAD3A UCSF GRCh37 1 1464667 1464667 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 15 40 0 ENST00000378755.5:c.1714G>A p.Gly572Ser p.G572S ENST00000378755 NM_018188.3 572 Ggc/Agc 0 +ATF7IP UCSF GRCh37 12 14631306 14631306 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 125 271 0 ENST00000261168.4:c.2997G>A p.Val999= p.V999= ENST00000261168 NM_018179.3 999 gtG/gtA 0 +ATG14 UCSF GRCh37 14 55836494 55836494 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 102 62 154 0 ENST00000247178.5:c.1322C>T p.Pro441Leu p.P441L ENST00000247178 NM_014924.4 441 cCc/cTc 0 +ATG2B UCSF GRCh37 14 96772039 96772039 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 65 127 0 ENST00000359933.4:c.4620C>T p.His1540= p.H1540= ENST00000359933 NM_018036.5 1540 caC/caT 0 +ATG3 UCSF GRCh37 3 112280342 112280342 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 16 60 0 ENST00000283290.5:c.34G>A p.Ala12Thr p.A12T ENST00000283290 NM_022488.4 12 Gca/Aca 0 +ATG9B UCSF GRCh37 7 150720273 150720273 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 172 116 229 0 ENST00000377974.2:c.680C>T p.Thr227Ile p.T227I ENST00000377974 227 aCc/aTc 0 +ATIC UCSF GRCh37 2 216177284 216177284 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 91 211 0 ENST00000236959.9:c.83G>A p.Gly28Asp p.G28D ENST00000236959 NM_004044.6 28 gGt/gAt 0 +ATM UCSF GRCh37 11 108183179 108183179 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 94 231 0 ENST00000278616.4:c.5960C>T p.Ser1987Phe p.S1987F ENST00000278616 NM_000051.3 1987 tCt/tTt 0 +ATP10D UCSF GRCh37 4 47537949 47537949 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 93 156 0 ENST00000273859.3:c.914G>A p.Ser305Asn p.S305N ENST00000273859 NM_020453.3 305 aGt/aAt 0 +ATP11B UCSF GRCh37 3 182554943 182554943 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 61 138 0 ENST00000323116.5:c.637C>T p.Pro213Ser p.P213S ENST00000323116 NM_014616.2 213 Cca/Tca 0 +ATP13A1 UCSF GRCh37 19 19767531 19767531 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 46 123 0 ENST00000357324.6:c.1021C>T p.Leu341= p.L341= ENST00000357324 NM_020410.2 341 Ctg/Ttg 0 +ATP13A5 UCSF GRCh37 3 193007755 193007755 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 65 132 0 ENST00000342358.4:c.2942C>T p.Ser981Phe p.S981F ENST00000342358 NM_198505.2 981 tCc/tTc 0 +ATP13A5 UCSF GRCh37 3 193032873 193032873 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 135 87 238 0 ENST00000342358.4:c.2046G>A p.Glu682= p.E682= ENST00000342358 NM_198505.2 682 gaG/gaA 0 +ATP1A2 UCSF GRCh37 1 160099137 160099137 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 137 236 0 ENST00000361216.3:c.1408G>A p.Asp470Asn p.D470N ENST00000361216 NM_000702.3 470 Gac/Aac 0 +ATP1A4 UCSF GRCh37 1 160136808 160136808 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 60 127 0 ENST00000368081.4:c.1297G>A p.Ala433Thr p.A433T ENST00000368081 NM_144699.3 433 Gct/Act 0 +ATP2A1 UCSF GRCh37 16 28893772 28893772 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 146 42 103 0 ENST00000357084.3:c.325G>A p.Glu109Lys p.E109K ENST00000357084 NM_173201.3 109 Gag/Aag 0 +ATP2B1 UCSF GRCh37 12 89992395 89992395 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 215 142 282 0 ENST00000428670.3:c.3351+499C>T *1117* ENST00000428670 0 +ATP2B2 UCSF GRCh37 3 10401790 10401790 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 23 74 0 ENST00000360273.2:c.1677C>T p.Gly559= p.G559= ENST00000360273 NM_001001331.2 559 ggC/ggT 0 +ATP2B4 UCSF GRCh37 1 203676351 203676351 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 44 114 0 ENST00000357681.5:c.1314G>A p.Lys438= p.K438= ENST00000357681 NM_001684.4 438 aaG/aaA 0 +ATP4A UCSF GRCh37 19 36051518 36051518 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 22 40 0 ENST00000262623.3:c.535-1G>A p.X179_splice ENST00000262623 NM_000704.2 0 +ATP5B UCSF GRCh37 12 57036564 57036564 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 80 166 0 ENST00000262030.3:c.844G>A p.Val282Ile p.V282I ENST00000262030 NM_001686.3 282 Gta/Ata 0 +ATP5D UCSF GRCh37 19 1244102 1244102 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 10 16 0 ENST00000215375.2:c.302G>A p.Ser101Asn p.S101N ENST00000215375 NM_001687.4 101 aGc/aAc 0 +ATP6V1B1 UCSF GRCh37 2 71191996 71191996 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 55 91 0 ENST00000234396.4:c.1378+1G>A p.X460_splice ENST00000234396 NM_001692.3 0 +ATP7B UCSF GRCh37 13 52511448 52511448 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 62 138 0 ENST00000242839.4:c.3985C>T p.Leu1329= p.L1329= ENST00000242839 NM_000053.3 1329 Ctg/Ttg 0 +ATP8B2 UCSF GRCh37 1 154310054 154310054 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 111 219 0 ENST00000368489.3:c.1133+34G>A *378* ENST00000368489 NM_020452.3 0 +ATP8B4 UCSF GRCh37 15 50190448 50190448 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 53 100 0 ENST00000284509.6:c.2290G>A p.Ala764Thr p.A764T ENST00000284509 NM_024837.3 764 Gct/Act 0 +ATPIF1 UCSF GRCh37 1 28562889 28562889 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 62 143 0 ENST00000335514.5:c.105G>A p.Arg35= p.R35= ENST00000335514 NM_016311.4 35 cgG/cgA 0 +ATRN UCSF GRCh37 20 3624900 3624900 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 93 176 0 ENST00000262919.5:c.4150C>T p.Pro1384Ser p.P1384S ENST00000262919 NM_139321.2 1384 Cct/Tct 0 +ATRN UCSF GRCh37 20 3624889 3624889 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 77 162 0 ENST00000262919.5:c.4139G>A p.Gly1380Asp p.G1380D ENST00000262919 NM_139321.2 1380 gGt/gAt 0 +ATRN UCSF GRCh37 20 3556596 3556596 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 60 138 0 ENST00000262919.5:c.2214+1G>A p.X738_splice ENST00000262919 NM_139321.2 0 +ATRN UCSF GRCh37 20 3575208 3575208 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 36 23 78 0 ENST00000262919.5:c.3405C>T p.Asp1135= p.D1135= ENST00000262919 NM_139321.2 1135 gaC/gaT 0 +ATRX UCSF GRCh37 X 76918998 76918999 + frameshift_variant Frame_Shift_Ins INS - - A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 62 0 ENST00000373344.5:c.3993dup p.Lys1332Ter p.K1332* ENST00000373344 NM_000489.3 1331 tct/tcTt 0 +ATXN1 UCSF GRCh37 6 16326873 16326873 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 49 117 1 ENST00000244769.4:c.1669G>A p.Val557Met p.V557M ENST00000244769 NM_000332.3 557 Gtg/Atg 0 +ATXN7L1 UCSF GRCh37 7 105254967 105254967 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 85 165 0 ENST00000419735.3:c.1814C>T p.Ser605Phe p.S605F ENST00000419735 NM_020725.1 605 tCc/tTc 0 +AURKC UCSF GRCh37 19 57744827 57744827 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 65 150 0 ENST00000302804.7:c.436-1G>A p.X146_splice ENST00000302804 NM_001015878.1 0 +AUTS2 UCSF GRCh37 7 69755436 69755436 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 111 208 0 ENST00000342771.4:c.661-145302C>T *221* ENST00000342771 NM_015570.2 0 +AVP UCSF GRCh37 20 3065294 3065294 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 80 129 0 ENST00000380293.3:c.27C>T p.Cys9= p.C9= ENST00000380293 NM_000490.4 9 tgC/tgT 0 +AVPI1 UCSF GRCh37 10 99439523 99439523 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 16 66 0 ENST00000370626.3:c.140G>A p.Gly47Glu p.G47E ENST00000370626 NM_021732.2 47 gGg/gAg 0 +AVPR1B UCSF GRCh37 1 206224614 206224614 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 48 133 0 ENST00000367126.4:c.174C>T p.Thr58= p.T58= ENST00000367126 NM_000707.3 58 acC/acT 0 +AXIN2 UCSF GRCh37 17 63554369 63554369 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 183 128 254 0 ENST00000307078.5:c.370G>A p.Asp124Asn p.D124N ENST00000307078 NM_004655.3 124 Gat/Aat 0 +AXIN2 UCSF GRCh37 17 63526149 63526149 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 91 195 0 ENST00000307078.5:c.2477C>T p.Thr826Met p.T826M ENST00000307078 NM_004655.3 826 aCg/aTg 0 +AZI2 UCSF GRCh37 3 28378370 28378370 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 76 186 0 ENST00000479665.1:c.446G>A p.Arg149Lys p.R149K ENST00000479665 NM_022461.4 149 aGg/aAg 0 +B3GALT5 UCSF GRCh37 21 41033171 41033171 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 82 214 0 ENST00000380620.4:c.685G>A p.Val229Met p.V229M ENST00000380620 229 Gtg/Atg 0 +B3GNT7 UCSF GRCh37 2 232262835 232262835 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 41 93 0 ENST00000287590.5:c.405C>T p.Tyr135= p.Y135= ENST00000287590 NM_145236.2 135 taC/taT 0 +B4GALNT2 UCSF GRCh37 17 47210398 47210398 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 24 37 0 ENST00000300404.2:c.11C>T p.Ala4Val p.A4V ENST00000300404 NM_153446.2 4 gCt/gTt 0 +B4GALNT2 UCSF GRCh37 17 47246984 47246984 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 58 142 0 ENST00000300404.2:c.1595C>T p.Ala532Val p.A532V ENST00000300404 NM_153446.2 532 gCt/gTt 0 +B4GALNT2 UCSF GRCh37 17 47247083 47247083 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 47 41 99 0 ENST00000300404.2:c.1694C>T p.Ala565Val p.A565V ENST00000300404 NM_153446.2 565 gCc/gTc 0 +B4GALT5 UCSF GRCh37 20 48257080 48257080 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 82 198 1 ENST00000371711.4:c.729C>T p.Arg243= p.R243= ENST00000371711 NM_004776.3 243 cgC/cgT 0 +BACH1 UCSF GRCh37 21 30714969 30714969 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 61 183 0 ENST00000399921.1:c.2026C>T p.Pro676Ser p.P676S ENST00000399921 NM_206866.1 676 Cct/Tct 0 +BACH2 UCSF GRCh37 6 90718495 90718495 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 67 145 0 ENST00000257749.4:c.69C>T p.Ile23= p.I23= ENST00000257749 NM_021813.2 23 atC/atT 0 +BAG2 UCSF GRCh37 6 57048790 57048790 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 76 183 0 ENST00000370693.5:c.438G>A p.Val146= p.V146= ENST00000370693 NM_004282.3 146 gtG/gtA 0 +BAIAP3 UCSF GRCh37 16 1397301 1397301 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 36 9 31 0 ENST00000324385.5:c.2859C>T p.Ala953= p.A953= ENST00000324385 NM_003933.4 953 gcC/gcT 0 +BANK1 UCSF GRCh37 4 102984291 102984291 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 33 108 0 ENST00000322953.4:c.2208C>T p.Val736= p.V736= ENST00000322953 NM_017935.4 736 gtC/gtT 0 +BAZ2B UCSF GRCh37 2 160269006 160269006 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 51 101 0 ENST00000392783.2:c.2517G>A p.Arg839= p.R839= ENST00000392783 NM_013450.2 839 agG/agA 0 +BBS7 UCSF GRCh37 4 122768661 122768661 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 91 181 0 ENST00000264499.4:c.935G>A p.Gly312Asp p.G312D ENST00000264499 NM_176824.2 312 gGc/gAc 0 +BBX UCSF GRCh37 3 107497265 107497265 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 84 194 0 ENST00000325805.8:c.2102C>T p.Pro701Leu p.P701L ENST00000325805 701 cCt/cTt 0 +BCAR3 UCSF GRCh37 1 94032835 94032835 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 64 119 0 ENST00000370244.1:c.2299+1G>A p.X767_splice ENST00000370244 NM_001261408.1 0 +BCAT2 UCSF GRCh37 19 49300543 49300543 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 23 40 0 ENST00000316273.6:c.743G>A p.Gly248Asp p.G248D ENST00000316273 NM_001190.3 248 gGc/gAc 0 +BCL11A UCSF GRCh37 2 60688867 60688867 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 73 113 0 ENST00000335712.6:c.1180G>A p.Val394Met p.V394M ENST00000335712 NM_022893.3 394 Gtg/Atg 0 +BCL11B UCSF GRCh37 14 99723979 99723979 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 67 129 0 ENST00000357195.3:c.256G>A p.Gly86Ser p.G86S ENST00000357195 NM_138576.2 86 Ggt/Agt 0 +BCL11B UCSF GRCh37 14 99724090 99724090 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 58 107 0 ENST00000357195.3:c.145G>A p.Gly49Ser p.G49S ENST00000357195 NM_138576.2 49 Ggt/Agt 0 +BCL9L UCSF GRCh37 11 118770897 118770897 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 10 47 0 ENST00000334801.3:c.3135G>A p.Pro1045= p.P1045= ENST00000334801 NM_182557.2 1045 ccG/ccA 0 +BCLAF1 UCSF GRCh37 6 136597646 136597646 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 110 83 246 0 ENST00000531224.1:c.1017G>A p.Arg339= p.R339= ENST00000531224 NM_001077441.1 339 agG/agA 0 +BCORL1 UCSF GRCh37 X 129148508 129148508 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 7 50 77 0 ENST00000540052.1:c.1760C>T p.Thr587Ile p.T587I ENST00000540052 NM_021946.4 587 aCc/aTc 0 +BDP1 UCSF GRCh37 5 70819776 70819776 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 72 176 0 ENST00000358731.4:c.5398C>T p.Pro1800Ser p.P1800S ENST00000358731 NM_018429.2 1800 Ccg/Tcg 0 +BEX2 UCSF GRCh37 X 102564611 102564611 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 152 153 0 ENST00000536889.1:c.390G>A p.Lys130= p.K130= ENST00000536889 NM_001168400.1 130 aaG/aaA 0 +BHLHE40 UCSF GRCh37 3 5024966 5024966 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 317 75 178 0 ENST00000256495.3:c.828C>T p.Gly276= p.G276= ENST00000256495 NM_003670.2 276 ggC/ggT 0 +BIN1 UCSF GRCh37 2 127808783 127808783 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 20 33 0 ENST00000316724.5:c.1408C>T p.Pro470Ser p.P470S ENST00000316724 NM_139343.2 470 Cct/Tct 0 +BLM UCSF GRCh37 15 91328173 91328173 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 139 252 0 ENST00000355112.3:c.2685C>T p.Cys895= p.C895= ENST00000355112 NM_000057.2 895 tgC/tgT 0 +BMP4 UCSF GRCh37 14 54417031 54417031 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 50 109 0 ENST00000245451.4:c.946G>A p.Asp316Asn p.D316N ENST00000245451 NM_001202.3 316 Gac/Aac 0 +BOD1L UCSF GRCh37 4 13603033 13603033 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 222 159 354 0 ENST00000040738.5:c.5491G>A p.Asp1831Asn p.D1831N ENST00000040738 NM_148894.2 1831 Gac/Aac 0 +BOD1L UCSF GRCh37 4 13616011 13616011 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 80 212 0 ENST00000040738.5:c.983G>A p.Ser328Asn p.S328N ENST00000040738 NM_148894.2 328 aGc/aAc 0 +BPHL UCSF GRCh37 6 3140744 3140744 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 166 88 214 0 ENST00000380379.5:c.788+1G>A p.X263_splice ENST00000380379 NM_004332.2 0 +BPIFB1 UCSF GRCh37 20 31897518 31897518 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 74 54 138 1 ENST00000253354.1:c.1400C>T p.Ala467Val p.A467V ENST00000253354 NM_033197.2 467 gCc/gTc 0 +BPIFB3 UCSF GRCh37 20 31644420 31644420 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 77 180 0 ENST00000375494.3:c.197G>A p.Gly66Asp p.G66D ENST00000375494 NM_182658.1 66 gGc/gAc 0 +BPTF UCSF GRCh37 17 65955886 65955886 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 61 112 0 ENST00000306378.6:c.8156C>T p.Ser2719Phe p.S2719F ENST00000306378 NM_182641.3 2719 tCc/tTc 0 +BRCA1 UCSF GRCh37 17 41215370 41215370 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 45 125 0 ENST00000357654.3:c.5173G>A p.Glu1725Lys p.E1725K ENST00000357654 NM_007294.3 1725 Gaa/Aaa 0 +BRCA2 UCSF GRCh37 13 32910602 32910602 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 61 148 0 ENST00000380152.3:c.2110C>T p.Pro704Ser p.P704S ENST00000380152 704 Cca/Tca 0 +BRCA2 UCSF GRCh37 13 32930720 32930720 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 85 262 0 ENST00000380152.3:c.7591G>A p.Val2531Ile p.V2531I ENST00000380152 2531 Gtt/Att 0 +BRD1 UCSF GRCh37 22 50187939 50187939 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 43 93 0 ENST00000216267.8:c.2102A>T p.Asp701Val p.D701V ENST00000216267 NM_014577.1 701 gAc/gTc 0 +BRD2 UCSF GRCh37 6 32944590 32944590 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 160 132 238 0 ENST00000395289.2:c.1077G>A p.Glu359= p.E359= ENST00000395289 359 gaG/gaA 0 +BRF1 UCSF GRCh37 14 105685573 105685573 + splice_region_variant,intron_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 51 126 0 ENST00000546474.1:c.1378-4C>T p.X460_splice ENST00000546474 NM_001519.3 0 +BRI3 UCSF GRCh37 7 97920429 97920429 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 48 118 0 ENST00000297290.3:c.252G>A p.Gly84= p.G84= ENST00000297290 NM_015379.4 84 ggG/ggA 0 +BRPF1 UCSF GRCh37 3 9775866 9775866 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 60 131 0 ENST00000383829.2:c.42G>A p.Leu14= p.L14= ENST00000383829 NM_001003694.1 14 ttG/ttA 0 +BRPF3 UCSF GRCh37 6 36178173 36178173 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 78 146 0 ENST00000357641.6:c.2047C>T p.Arg683Trp p.R683W ENST00000357641 NM_015695.2 683 Cgg/Tgg 0 +BRPF3 UCSF GRCh37 6 36185780 36185780 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 62 121 0 ENST00000357641.6:c.3076G>A p.Ala1026Thr p.A1026T ENST00000357641 NM_015695.2 1026 Gct/Act 0 +BSND UCSF GRCh37 1 55473906 55473906 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 23 78 0 ENST00000371265.4:c.568G>A p.Gly190Ser p.G190S ENST00000371265 NM_057176.2 190 Ggc/Agc 0 +BTBD9 UCSF GRCh37 6 38545422 38545422 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 74 182 0 ENST00000481247.1:c.1108C>T p.Leu370= p.L370= ENST00000481247 NM_052893.1 370 Ctg/Ttg 0 +BTD UCSF GRCh37 3 15686403 15686403 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 99 209 0 ENST00000303498.5:c.1040C>T p.Ala347Val p.A347V ENST00000303498 NM_000060.2 347 gCa/gTa 0 +BTN2A2 UCSF GRCh37 6 26385433 26385433 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 62 162 0 ENST00000356709.4:c.285G>A p.Glu95= p.E95= ENST00000356709 NM_001197240.1 95 gaG/gaA 0 +BUD13 UCSF GRCh37 11 116633778 116633778 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 96 257 0 ENST00000260210.4:c.527C>T p.Pro176Leu p.P176L ENST00000260210 NM_032725.3 176 cCt/cTt 0 +BZRAP1 UCSF GRCh37 17 56382433 56382433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 28 63 0 ENST00000343736.4:c.5533G>A p.Ala1845Thr p.A1845T ENST00000343736 1845 Gct/Act 0 +C10orf10 UCSF GRCh37 10 45473473 45473473 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 39 77 0 ENST00000298295.3:c.6G>A p.Arg2= p.R2= ENST00000298295 NM_007021.3 2 agG/agA 0 +C10orf12 UCSF GRCh37 10 98744434 98744434 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 72 157 0 ENST00000286067.2:c.3287G>A p.Ser1096Asn p.S1096N ENST00000286067 NM_015652.2 1096 aGc/aAc 0 +C10orf92 UCSF GRCh37 10 134647012 134647012 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 34 141 0 ENST00000368586.5:c.6967G>A p.Val2323Ile p.V2323I ENST00000368586 NM_001200049.2 2323 Gtt/Att 0 +C11orf2 UCSF GRCh37 11 64875733 64875733 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 18 6 26 0 ENST00000279281.3:c.790C>T p.Pro264Ser p.P264S ENST00000279281 NM_013265.3 264 Cct/Tct 0 +C11orf34 UCSF GRCh37 11 112123133 112123133 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 59 141 0 ENST00000338832.2:c.387-1G>A p.X129_splice ENST00000338832 NM_001145024.1 0 +C11orf41 UCSF GRCh37 11 33680437 33680437 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 42 33 54 0 ENST00000321505.4:c.5109T>C p.Asn1703= p.N1703= ENST00000321505 1703 aaT/aaC 0 +C11orf67 UCSF GRCh37 11 77553552 77553552 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 48 136 0 ENST00000526415.1:c.10C>T p.Pro4Ser p.P4S ENST00000526415 4 Cct/Tct 0 +C11orf80 UCSF GRCh37 11 66583523 66583523 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 98 202 0 ENST00000360962.4:c.1190-1G>A p.X397_splice ENST00000360962 NM_024650.3 0 +C12orf41 UCSF GRCh37 12 49054188 49054188 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 94 192 0 ENST00000420613.2:c.1188G>A p.Glu396= p.E396= ENST00000420613 NM_017822.3 396 gaG/gaA 0 +C12orf51 UCSF GRCh37 12 112605305 112605305 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 34 102 0 ENST00000550722.1:c.11912G>A p.Gly3971Glu p.G3971E ENST00000550722 NM_001109662.3 3971 gGg/gAg 0 +C13orf35 UCSF GRCh37 13 113333890 113333890 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 17 83 0 ENST00000356049.1:c.197G>A p.Gly66Asp p.G66D ENST00000356049 NM_207440.1 66 gGt/gAt 0 +C14orf169 UCSF GRCh37 14 73959400 73959400 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 56 48 111 0 ENST00000304061.5:n.1755G>A *585* ENST00000304061 0 +C14orf93 UCSF GRCh37 14 23467838 23467838 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 60 127 0 ENST00000299088.6:c.395G>A p.Gly132Glu p.G132E ENST00000299088 NM_001130708.1 132 gGg/gAg 0 +C15orf2 UCSF GRCh37 15 24921955 24921955 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 72 143 0 ENST00000329468.2:c.941G>A p.Ser314Asn p.S314N ENST00000329468 NM_018958.2 314 aGc/aAc 0 +C15orf38 UCSF GRCh37 15 90454051 90454051 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 44 77 0 ENST00000357484.5:c.93G>A p.Gly31= p.G31= ENST00000357484 NM_182616.2 31 ggG/ggA 0 +C15orf48 UCSF GRCh37 15 45723270 45723270 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 81 231 0 ENST00000344300.3:c.108G>A p.Trp36Ter p.W36* ENST00000344300 NM_032413.3 36 tgG/tgA 0 +C16orf11 UCSF GRCh37 16 613964 613964 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 8 13 0 ENST00000409413.3:c.670G>A p.Gly224Arg p.G224R ENST00000409413 NM_145270.2 224 Ggg/Agg 0 +C16orf79 UCSF GRCh37 16 2260557 2260557 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 27 37 0 ENST00000328540.3:c.146G>A p.Gly49Glu p.G49E ENST00000328540 NM_182563.3 49 gGa/gAa 0 +C16orf88 UCSF GRCh37 16 19722714 19722714 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 57 100 0 ENST00000219837.7:c.967G>A p.Asp323Asn p.D323N ENST00000219837 NM_001012991.2 323 Gat/Aat 0 +C16orf93 UCSF GRCh37 16 30770562 30770562 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 64 150 0 ENST00000543610.1:c.664C>T p.Leu222= p.L222= ENST00000543610 NM_001014979.2 222 Ctg/Ttg 0 +C17orf104 UCSF GRCh37 17 42745396 42745396 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 79 223 0 ENST00000409122.2:c.2117C>T p.Ser706Phe p.S706F ENST00000409122 NM_001145080.2 706 tCc/tTc 0 +C17orf108 UCSF GRCh37 17 26207345 26207345 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 85 210 0 ENST00000379103.3:c.174G>A p.Gln58= p.Q58= ENST00000379103 NM_001076680.1 58 caG/caA 0 +C17orf61 UCSF GRCh37 17 7306428 7306428 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 71 141 0 ENST00000302422.3:c.299G>A p.Gly100Glu p.G100E ENST00000302422 NM_152766.3 100 gGa/gAa 0 +C17orf74 UCSF GRCh37 17 7330367 7330367 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 22 49 0 ENST00000333870.3:c.1057C>T p.Leu353Phe p.L353F ENST00000333870 NM_175734.4 353 Ctt/Ttt 0 +C19orf55 UCSF GRCh37 19 36258896 36258896 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 8 17 0 ENST00000544099.1:c.1149G>A p.Pro383= p.P383= ENST00000544099 383 ccG/ccA 0 +C1orf101 UCSF GRCh37 1 244715903 244715903 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 103 214 0 ENST00000366534.4:c.816C>T p.Ile272= p.I272= ENST00000366534 NM_001130957.1 272 atC/atT 0 +C1orf141 UCSF GRCh37 1 67559268 67559268 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 54 119 0 ENST00000371007.2:c.623C>T p.Pro208Leu p.P208L ENST00000371007 208 cCc/cTc 0 +C1orf146 UCSF GRCh37 1 92710342 92710342 + synonymous_variant Silent SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 74 50 131 0 ENST00000370375.3:c.336G>C p.Leu112= p.L112= ENST00000370375 NM_001012425.1 112 ctG/ctC 0 +C1orf172 UCSF GRCh37 1 27278215 27278215 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 40 93 0 ENST00000320567.5:c.657C>T p.Phe219= p.F219= ENST00000320567 NM_152365.2 219 ttC/ttT 0 +C1orf174 UCSF GRCh37 1 3806606 3806606 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 69 163 0 ENST00000361605.3:c.650C>T p.Ser217Leu p.S217L ENST00000361605 NM_207356.2 217 tCa/tTa 0 +C1orf177 UCSF GRCh37 1 55273208 55273208 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 14 22 0 ENST00000371273.3:c.202G>A p.Gly68Ser p.G68S ENST00000371273 NM_001110533.1 68 Ggc/Agc 0 +C1orf185 UCSF GRCh37 1 51578242 51578242 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 48 137 0 ENST00000371759.2:c.122+1G>A p.X41_splice ENST00000371759 NM_001136508.1 0 +C1orf201 UCSF GRCh37 1 24687346 24687346 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 153 138 261 0 ENST00000374409.1:c.923G>A p.Gly308Asp p.G308D ENST00000374409 NM_001199012.1 308 gGc/gAc 0 +C1orf55 UCSF GRCh37 1 226176044 226176044 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 89 179 0 ENST00000272091.7:c.687G>A p.Glu229= p.E229= ENST00000272091 NM_152608.3 229 gaG/gaA 0 +C1orf9 UCSF GRCh37 1 172525047 172525047 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 46 122 0 ENST00000263688.3:c.327G>A p.Glu109= p.E109= ENST00000263688 NM_014283.3 109 gaG/gaA 0 +C1QC UCSF GRCh37 1 22974240 22974240 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 49 132 0 ENST00000374639.3:c.702C>T p.Asp234= p.D234= ENST00000374639 NM_001114101.1 234 gaC/gaT 0 +C1QL1 UCSF GRCh37 17 43037688 43037688 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 53 93 0 ENST00000253407.3:c.645C>T p.Tyr215= p.Y215= ENST00000253407 NM_006688.3 215 taC/taT 0 +C1QTNF7 UCSF GRCh37 4 15444252 15444252 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 97 193 0 ENST00000295297.4:c.720G>A p.Gly240= p.G240= ENST00000295297 NM_001135170.1 240 ggG/ggA 0 +C1S UCSF GRCh37 12 7172428 7172428 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 57 128 0 ENST00000406697.1:c.542C>T p.Thr181Ile p.T181I ENST00000406697 181 aCt/aTt 0 +C20orf118 UCSF GRCh37 20 35515860 35515860 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 85 155 0 ENST00000217320.3:c.441C>T p.Val147= p.V147= ENST00000217320 NM_080628.1 147 gtC/gtT 0 +C20orf152 UCSF GRCh37 20 34571991 34571991 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 60 110 0 ENST00000349339.1:c.495G>A p.Lys165= p.K165= ENST00000349339 NM_080834.2 165 aaG/aaA 0 +C20orf173 UCSF GRCh37 20 34117064 34117064 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 33 76 0 ENST00000444723.1:c.139C>T p.Pro47Ser p.P47S ENST00000444723 NM_001145350.1 47 Cct/Tct 0 +C20orf194 UCSF GRCh37 20 3296417 3296417 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 119 76 171 0 ENST00000252032.9:c.1555G>A p.Val519Ile p.V519I ENST00000252032 NM_001009984.2 519 Gta/Ata 0 +C20orf194 UCSF GRCh37 20 3305607 3305607 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 119 95 219 0 ENST00000252032.9:c.1197G>A p.Glu399= p.E399= ENST00000252032 NM_001009984.2 399 gaG/gaA 0 +C20orf203 UCSF GRCh37 20 31238448 31238448 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 13 20 0 ENST00000608990.1:n.944G>A *315* ENST00000608990 0 +C20orf4 UCSF GRCh37 20 34828399 34828399 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 69 163 0 ENST00000373932.3:c.609G>A p.Gly203= p.G203= ENST00000373932 NM_015511.4 203 ggG/ggA 0 +C20orf43 UCSF GRCh37 20 55088414 55088414 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 13 29 0 ENST00000023939.4:c.521G>A p.Gly174Asp p.G174D ENST00000023939 NM_016407.3 174 gGc/gAc 0 +C20orf54 UCSF GRCh37 20 745983 745983 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 67 43 87 0 ENST00000217254.7:c.436G>A p.Gly146Arg p.G146R ENST00000217254 NM_033409.3 146 Gga/Aga 0 +C20orf79 UCSF GRCh37 20 18794477 18794477 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 63 143 0 ENST00000377428.2:c.18C>T p.Asp6= p.D6= ENST00000377428 NM_178483.2 6 gaC/gaT 0 +C22orf13 UCSF GRCh37 22 24944004 24944004 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 51 77 0 ENST00000407471.3:c.166G>A p.Ala56Thr p.A56T ENST00000407471 NM_001284251.1 56 Gcc/Acc 0 +C22orf28 UCSF GRCh37 22 32793982 32793982 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 90 179 0 ENST00000216038.5:c.760G>A p.Val254Met p.V254M ENST00000216038 NM_014306.4 254 Gtg/Atg 0 +C2CD3 UCSF GRCh37 11 73789637 73789637 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 85 200 0 ENST00000313663.7:c.4126G>A p.Glu1376Lys p.E1376K ENST00000313663 NM_015531.4 1376 Gaa/Aaa 0 +C2orf16 UCSF GRCh37 2 27799614 27799614 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 82 138 0 ENST00000408964.2:c.175G>A p.Asp59Asn p.D59N ENST00000408964 NM_032266.3 59 Gat/Aat 0 +C2orf40 UCSF GRCh37 2 106694240 106694240 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.002,1000g2011may_all_0.0054,snp132_rs117849769 P18_Rec Untested WXS Illumina HiSeq 129 106 196 0 ENST00000238044.3:c.305C>T p.Thr102Ile p.T102I ENST00000238044 NM_032411.2 102 aCc/aTc 0 +C2orf44 UCSF GRCh37 2 24260791 24260791 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 76 151 0 ENST00000295148.4:c.1574C>T p.Pro525Leu p.P525L ENST00000295148 NM_025203.2 525 cCc/cTc 0 +C2orf67 UCSF GRCh37 2 210896241 210896241 + stop_gained Nonsense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 194 151 283 1 ENST00000281772.9:c.2059G>T p.Gly687Ter p.G687* ENST00000281772 NM_152519.2 687 Gga/Tga 0 +C2orf68 UCSF GRCh37 2 85839061 85839061 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 13 23 0 ENST00000306336.5:c.47G>A p.Gly16Glu p.G16E ENST00000306336 NM_001013649.3 16 gGg/gAg 0 +C3orf25 UCSF GRCh37 3 129140431 129140431 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 74 197 0 ENST00000505956.1:c.265G>A p.Val89Ile p.V89I ENST00000505956 NM_207307.1 89 Gtt/Att 0 +C3orf30 UCSF GRCh37 3 118865880 118865880 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 122 85 163 0 ENST00000295622.1:c.844G>A p.Ala282Thr p.A282T ENST00000295622 NM_152539.2 282 Gct/Act 0 +C3orf30 UCSF GRCh37 3 118865621 118865621 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 131 243 0 ENST00000295622.1:c.585C>T p.Asp195= p.D195= ENST00000295622 NM_152539.2 195 gaC/gaT 0 +C4orf41 UCSF GRCh37 4 184628085 184628085 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 55 146 0 ENST00000334690.6:c.3181C>T p.Leu1061Phe p.L1061F ENST00000334690 NM_021942.5 1061 Ctc/Ttc 0 +C4orf46 UCSF GRCh37 4 159590829 159590829 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 75 146 0 ENST00000379205.4:c.278G>A p.Arg93His p.R93H ENST00000379205 NM_001008393.3 93 cGt/cAt 0 +C5 UCSF GRCh37 9 123742447 123742447 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 164 162 0 ENST00000223642.1:c.3572C>T p.Ser1191Phe p.S1191F ENST00000223642 NM_001735.2 1191 tCt/tTt 0 +C5AR1 UCSF GRCh37 19 47823952 47823952 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 66 176 0 ENST00000355085.3:c.918C>T p.Gly306= p.G306= ENST00000355085 NM_001736.3 306 ggC/ggT 0 +C5orf22 UCSF GRCh37 5 31538470 31538470 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 59 191 0 ENST00000325366.9:c.481C>T p.Pro161Ser p.P161S ENST00000325366 NM_018356.2 161 Cct/Tct 0 +C5orf51 UCSF GRCh37 5 41917241 41917241 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 130 67 188 0 ENST00000381647.2:c.725C>T p.Ala242Val p.A242V ENST00000381647 NM_175921.4 242 gCg/gTg 0 +C6orf132 UCSF GRCh37 6 42071557 42071557 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 22 55 0 ENST00000341865.4:c.3509G>A p.Gly1170Glu p.G1170E ENST00000341865 NM_001164446.1 1170 gGg/gAg 0 +C6orf165 UCSF GRCh37 6 88126492 88126492 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 51 125 0 ENST00000369562.4:c.578G>A p.Gly193Glu p.G193E ENST00000369562 NM_001031743.2 193 gGa/gAa 0 +C6orf174 UCSF GRCh37 6 127796620 127796620 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 50 154 0 ENST00000481848.2:c.2551G>A p.Asp851Asn p.D851N ENST00000481848 851 Gac/Aac 0 +C6orf211 UCSF GRCh37 6 151785748 151785748 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 27 67 0 ENST00000367294.3:c.553C>T p.Leu185= p.L185= ENST00000367294 NM_024573.1 185 Ctg/Ttg 0 +C6orf223 UCSF GRCh37 6 43970685 43970685 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 29 54 0 ENST00000336600.5:c.551C>T p.Pro184Leu p.P184L ENST00000336600 NM_001171992.1 184 cCc/cTc 0 +C6orf47 UCSF GRCh37 6 31627559 31627559 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 56 108 0 ENST00000375911.1:c.166C>T p.Pro56Ser p.P56S ENST00000375911 NM_021184.3 56 Ccc/Tcc 0 +C6orf70 UCSF GRCh37 6 170168254 170168254 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 47 116 0 ENST00000366773.3:c.1046G>A p.Gly349Glu p.G349E ENST00000366773 NM_018341.2 349 gGa/gAa 0 +C6orf97 UCSF GRCh37 6 151865852 151865852 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 79 205 0 ENST00000239374.7:c.588+1G>A p.X196_splice ENST00000239374 NM_025059.3 0 +C7orf47 UCSF GRCh37 7 100033560 100033560 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 22 0 ENST00000292330.2:c.362G>A p.Gly121Glu p.G121E ENST00000292330 NM_145030.2 121 gGg/gAg 0 +C7orf65 UCSF GRCh37 7 47698652 47698652 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 60 159 0 ENST00000408988.2:c.282C>T p.Thr94= p.T94= ENST00000408988 NM_001123065.1 94 acC/acT 0 +C8A UCSF GRCh37 1 57351790 57351790 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 85 210 0 ENST00000361249.3:c.1046G>A p.Gly349Asp p.G349D ENST00000361249 NM_000562.2 349 gGc/gAc 0 +C8orf37 UCSF GRCh37 8 96259901 96259901 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 61 155 0 ENST00000286688.5:c.568G>A p.Glu190Lys p.E190K ENST00000286688 NM_177965.3 190 Gaa/Aaa 0 +C8orf40 UCSF GRCh37 8 42407718 42407718 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 93 224 0 ENST00000438528.3:c.291C>T p.Asn97= p.N97= ENST00000438528 NM_001135676.1 97 aaC/aaT 0 +C9orf172 UCSF GRCh37 9 139739664 139739664 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 12 27 0 ENST00000436881.1:c.798G>A p.Glu266= p.E266= ENST00000436881 NM_001080482.2 266 gaG/gaA 0 +C9orf93 UCSF GRCh37 9 15571644 15571644 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 24 105 215 0 ENST00000380701.3:c.64G>A p.Val22Ile p.V22I ENST00000380701 NM_173550.2 22 Gta/Ata 0 +CA14 UCSF GRCh37 1 150234659 150234659 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 144 102 195 0 ENST00000369111.4:c.359G>A p.Gly120Glu p.G120E ENST00000369111 NM_012113.1 120 gGg/gAg 0 +CA4 UCSF GRCh37 17 58235074 58235074 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 69 179 0 ENST00000300900.4:c.438G>A p.Glu146= p.E146= ENST00000300900 NM_000717.3 146 gaG/gaA 0 +CA5A UCSF GRCh37 16 87925507 87925507 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 19 55 0 ENST00000309893.2:c.672C>T p.Cys224= p.C224= ENST00000309893 NM_001739.1 224 tgC/tgT 0 +CABS1 UCSF GRCh37 4 71201071 71201072 + frameshift_variant Frame_Shift_Del DEL CA CA G NOVEL P18_Rec Untested WXS Illumina HiSeq 46 0 ENST00000273936.5:c.315_316delinsG p.Ile106Ter p.I106* ENST00000273936 NM_033122.3 105 tcCAta/tcGta 0 +CABYR UCSF GRCh37 18 21736260 21736260 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 65 159 0 ENST00000399496.3:c.541+254G>A *181* ENST00000399496 NM_012189.3 0 +CACHD1 UCSF GRCh37 1 65131847 65131847 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 77 93 0 ENST00000290039.5:c.2231C>T p.Ser744Phe p.S744F ENST00000290039 NM_020925.2 744 tCc/tTc 0 +CACNA1A UCSF GRCh37 19 13470554 13470554 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 59 110 0 ENST00000360228.5:c.844C>T p.Pro282Ser p.P282S ENST00000360228 NM_001127222.1 282 Ccc/Tcc 0 +CACNA1D UCSF GRCh37 3 53707796 53707796 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 65 168 0 ENST00000288139.4:c.1173C>T p.Ile391= p.I391= ENST00000288139 NM_000720.3 391 atC/atT 0 +CACNA1E UCSF GRCh37 1 181762842 181762842 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 119 74 168 0 ENST00000367573.2:c.5940C>T p.Asn1980= p.N1980= ENST00000367573 NM_001205293.1 1980 aaC/aaT 0 +CACNA1F UCSF GRCh37 X 49088147 49088147 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 67 75 0 ENST00000376265.2:c.268G>A p.Glu90Lys p.E90K ENST00000376265 NM_005183.2 90 Gag/Aag 0 +CACNA1I UCSF GRCh37 22 40066139 40066139 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 95 221 0 ENST00000402142.3:c.4291G>A p.Val1431Met p.V1431M ENST00000402142 NM_021096.3 1431 Gtg/Atg 0 +CACNA1I UCSF GRCh37 22 40015336 40015336 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 48 121 0 ENST00000402142.3:c.504C>T p.Asp168= p.D168= ENST00000402142 NM_021096.3 168 gaC/gaT 0 +CACNA1S UCSF GRCh37 1 201018178 201018178 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 33 55 0 ENST00000362061.3:c.4291C>T p.Pro1431Ser p.P1431S ENST00000362061 NM_000069.2 1431 Ccc/Tcc 0 +CACNA1S UCSF GRCh37 1 201030429 201030429 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 59 98 0 ENST00000362061.3:c.3221C>T p.Thr1074Ile p.T1074I ENST00000362061 NM_000069.2 1074 aCt/aTt 0 +CACNA2D2 UCSF GRCh37 3 50402395 50402395 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 14 45 0 ENST00000479441.1:c.3236G>A p.Gly1079Asp p.G1079D ENST00000479441 1079 gGc/gAc 0 +CACNA2D2 UCSF GRCh37 3 50404897 50404897 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 29 73 0 ENST00000479441.1:c.2350C>T p.Pro784Ser p.P784S ENST00000479441 784 Ccc/Tcc 0 +CACNB1 UCSF GRCh37 17 37331830 37331830 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 48 121 0 ENST00000394303.3:c.1413G>A p.Glu471= p.E471= ENST00000394303 NM_000723.4 471 gaG/gaA 0 +CACNG1 UCSF GRCh37 17 65040959 65040959 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 30 71 0 ENST00000226021.3:c.183C>T p.Ile61= p.I61= ENST00000226021 NM_000727.3 61 atC/atT 0 +CADPS UCSF GRCh37 3 62478043 62478043 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 209 165 297 0 ENST00000383710.4:c.2806G>A p.Ala936Thr p.A936T ENST00000383710 NM_003716.3 936 Gcc/Acc 0 +CADPS2 UCSF GRCh37 7 121960334 121960334 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 208 173 339 0 ENST00000449022.2:c.3776C>T p.Thr1259Ile p.T1259I ENST00000449022 NM_017954.10 1259 aCt/aTt 0 +CADPS2 UCSF GRCh37 7 122377059 122377059 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 86 197 0 ENST00000449022.2:c.403C>T p.Gln135Ter p.Q135* ENST00000449022 NM_017954.10 135 Caa/Taa 0 +CALCOCO1 UCSF GRCh37 12 54107963 54107963 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 6 32 91 1 ENST00000550804.1:c.1545G>A p.Trp515Ter p.W515* ENST00000550804 515 tgG/tgA 0 +CALR3 UCSF GRCh37 19 16593283 16593283 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 54 133 0 ENST00000269881.3:c.896C>T p.Ala299Val p.A299V ENST00000269881 NM_145046.4 299 gCc/gTc 0 +CAMK1G UCSF GRCh37 1 209783195 209783195 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 58 117 0 ENST00000009105.1:c.749-1G>A p.X250_splice ENST00000009105 0 +CAMK2G UCSF GRCh37 10 75612997 75612997 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 41 98 0 ENST00000322680.3:c.228C>T p.Leu76= p.L76= ENST00000322680 NM_172170.4 76 ctC/ctT 0 +CAMTA1 UCSF GRCh37 1 7723491 7723491 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 71 142 0 ENST00000303635.7:c.884G>A p.Gly295Glu p.G295E ENST00000303635 NM_015215.2 295 gGg/gAg 0 +CAPN11 UCSF GRCh37 6 44140111 44140111 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 18 36 0 ENST00000398776.1:c.482G>A p.Arg161Lys p.R161K ENST00000398776 NM_007058.3 161 aGa/aAa 0 +CAPN12 UCSF GRCh37 19 39226149 39226149 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 14 47 0 ENST00000328867.4:c.1619C>T p.Ser540Phe p.S540F ENST00000328867 NM_144691.3 540 tCt/tTt 0 +CAPNS1 UCSF GRCh37 19 36633571 36633571 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 100 179 0 ENST00000246533.3:c.261C>T p.Tyr87= p.Y87= ENST00000246533 NM_001749.2 87 taC/taT 0 +CAPZA1 UCSF GRCh37 1 113189886 113189886 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 96 228 0 ENST00000263168.3:c.94G>A p.Val32Ile p.V32I ENST00000263168 NM_006135.2 32 Gta/Ata 0 +CARD11 UCSF GRCh37 7 2977541 2977541 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 39 76 0 ENST00000396946.4:c.1143G>A p.Gln381= p.Q381= ENST00000396946 NM_032415.4 381 caG/caA 0 +CARD16 UCSF GRCh37 11 104912389 104912389 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 96 221 0 ENST00000375706.2:c.332G>A p.Arg111Lys p.R111K ENST00000375706 NM_001017534.1 111 aGa/aAa 0 +CARM1 UCSF GRCh37 19 11024706 11024706 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 15 47 0 ENST00000327064.4:c.823G>A p.Ala275Thr p.A275T ENST00000327064 NM_199141.1 275 Gcc/Acc 0 +CARNS1 UCSF GRCh37 11 67192040 67192040 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 18 10 26 0 ENST00000445895.2:c.2821C>T p.Pro941Ser p.P941S ENST00000445895 941 Cct/Tct 0 +CASP5 UCSF GRCh37 11 104871090 104871090 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 171 102 235 0 ENST00000393141.2:c.889G>A p.Asp297Asn p.D297N ENST00000393141 NM_004347.3 297 Gat/Aat 0 +CASP8AP2 UCSF GRCh37 6 90571890 90571890 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 131 89 223 0 ENST00000551025.1:n.1899G>A *633* ENST00000551025 0 +CASS4 UCSF GRCh37 20 55012249 55012249 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 86 168 0 ENST00000371336.3:c.66C>T p.Asn22= p.N22= ENST00000371336 NM_001164114.1 22 aaC/aaT 0 +CASZ1 UCSF GRCh37 1 10720317 10720317 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 31 71 0 ENST00000377022.3:c.782C>T p.Thr261Ile p.T261I ENST00000377022 NM_001079843.2 261 aCc/aTc 0 +CATSPER2 UCSF GRCh37 15 43924482 43924482 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 72 133 1 ENST00000321596.5:c.1476C>T p.Pro492= p.P492= ENST00000321596 492 ccC/ccT 0 +CCBL2 UCSF GRCh37 1 89414918 89414918 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 68 153 0 ENST00000260508.4:c.997G>A p.Asp333Asn p.D333N ENST00000260508 NM_001008661.2 333 Gat/Aat 0 +CCBP2 UCSF GRCh37 3 42906810 42906810 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 176 98 245 0 ENST00000422265.1:c.816G>A p.Leu272= p.L272= ENST00000422265 NM_001296.4 272 ctG/ctA 0 +CCDC102B UCSF GRCh37 18 66504265 66504265 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 154 127 250 0 ENST00000360242.5:c.265G>A p.Glu89Lys p.E89K ENST00000360242 NM_024781.2 89 Gaa/Aaa 0 +CCDC107 UCSF GRCh37 9 35661073 35661073 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 66 129 0 ENST00000426546.2:c.741G>A p.Arg247= p.R247= ENST00000426546 NM_001195201.1 247 cgG/cgA 0 +CCDC129 UCSF GRCh37 7 31691601 31691601 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 78 164 0 ENST00000451887.2:c.2838G>A p.Gln946= p.Q946= ENST00000451887 NM_001257968.1 946 caG/caA 0 +CCDC132 UCSF GRCh37 7 92963441 92963441 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 159 104 214 0 ENST00000305866.5:c.1990G>A p.Gly664Arg p.G664R ENST00000305866 NM_017667.3 664 Gga/Aga 0 +CCDC134 UCSF GRCh37 22 42209287 42209287 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 62 163 0 ENST00000255784.5:c.330G>A p.Glu110= p.E110= ENST00000255784 NM_024821.2 110 gaG/gaA 0 +CCDC135 UCSF GRCh37 16 57756942 57756942 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 82 156 0 ENST00000360716.3:c.1437G>A p.Trp479Ter p.W479* ENST00000360716 479 tgG/tgA 0 +CCDC149 UCSF GRCh37 4 24810064 24810064 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 47 85 0 ENST00000504487.1:c.1537G>A p.Asp513Asn p.D513N ENST00000504487 NM_001130726.2 513 Gac/Aac 0 +CCDC36 UCSF GRCh37 3 49294536 49294536 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 116 255 0 ENST00000438782.1:c.1606C>T p.Leu536Phe p.L536F ENST00000438782 536 Ctc/Ttc 0 +CCDC57 UCSF GRCh37 17 80141668 80141668 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 87 155 0 ENST00000392343.3:c.1193C>T p.Ser398Phe p.S398F ENST00000392343 398 tCc/tTc 0 +CCDC58 UCSF GRCh37 3 122078754 122078754 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 65 161 0 ENST00000291458.5:c.397C>T p.Arg133Cys p.R133C ENST00000291458 NM_001017928.2 133 Cgc/Tgc 0 +CCDC75 UCSF GRCh37 2 37316927 37316927 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 18 78 185 0 ENST00000608836.1:c.192G>A p.Lys64= p.K64= ENST00000608836 64 aaG/aaA 0 +CCDC77 UCSF GRCh37 12 550148 550148 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 58 161 0 ENST00000239830.4:c.1306C>T p.Gln436Ter p.Q436* ENST00000239830 NM_032358.3 436 Caa/Taa 0 +CCDC83 UCSF GRCh37 11 85630413 85630413 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 87 187 0 ENST00000280245.4:c.1195C>T p.Leu399= p.L399= ENST00000280245 NM_173556.3 399 Ctg/Ttg 0 +CCDC91 UCSF GRCh37 12 28459819 28459819 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 100 79 161 0 ENST00000545336.1:c.412A>G p.Ile138Val p.I138V ENST00000545336 138 Att/Gtt 0 +CCNDBP1 UCSF GRCh37 15 43483770 43483770 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 67 150 0 ENST00000300213.4:c.757G>A p.Ala253Thr p.A253T ENST00000300213 NM_012142.4 253 Gcc/Acc 0 +CCNE1 UCSF GRCh37 19 30303917 30303917 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 32 76 0 ENST00000262643.3:c.153G>A p.Arg51= p.R51= ENST00000262643 NM_001238.2 51 agG/agA 0 +CCNH UCSF GRCh37 5 86700661 86700661 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 33 74 0 ENST00000256897.4:c.689G>A p.Ser230Asn p.S230N ENST00000256897 NM_001239.3 230 aGt/aAt 0 +CCNK UCSF GRCh37 14 99977096 99977096 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 8 21 0 ENST00000389879.5:c.1720G>A p.Gly574Arg p.G574R ENST00000389879 NM_001099402.1 574 Ggg/Agg 0 +CCNT1 UCSF GRCh37 12 49089613 49089613 + splice_acceptor_variant Splice_Site SNP C C T snp132_rs11833923 P18_Rec Untested WXS Illumina HiSeq 19 47 133 0 ENST00000261900.3:c.707-1G>A p.X236_splice ENST00000261900 NM_001240.3 0 +CCNT2 UCSF GRCh37 2 135696633 135696633 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 76 190 0 ENST00000264157.5:c.430+1G>A p.X144_splice ENST00000264157 NM_058241.2 0 +CCR8 UCSF GRCh37 3 39374006 39374006 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 169 117 271 0 ENST00000326306.4:c.184G>A p.Val62Ile p.V62I ENST00000326306 NM_005201.3 62 Gtc/Atc 0 +CCRL1 UCSF GRCh37 3 132320132 132320132 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 477 84 638 0 ENST00000249887.2:c.891C>T p.Cys297= p.C297= ENST00000249887 NM_016557.3 297 tgC/tgT 0 +CCT7 UCSF GRCh37 2 73466919 73466919 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 102 216 0 ENST00000258091.5:c.155G>A p.Gly52Asp p.G52D ENST00000258091 NM_006429.3 52 gGc/gAc 0 +CCT7 UCSF GRCh37 2 73471675 73471675 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 77 173 0 ENST00000258091.5:c.450G>A p.Glu150= p.E150= ENST00000258091 NM_006429.3 150 gaG/gaA 0 +CCT8L2 UCSF GRCh37 22 17073014 17073014 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 62 149 0 ENST00000359963.3:c.427G>A p.Val143Ile p.V143I ENST00000359963 NM_014406.4 143 Gtc/Atc 0 +CD101 UCSF GRCh37 1 117559965 117559965 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 76 173 0 ENST00000256652.4:c.1482C>T p.Phe494= p.F494= ENST00000256652 NM_004258.5 494 ttC/ttT 0 +CD207 UCSF GRCh37 2 71062662 71062662 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 52 110 0 ENST00000410009.3:c.150G>A p.Thr50= p.T50= ENST00000410009 NM_015717.3 50 acG/acA 0 +CD2BP2 UCSF GRCh37 16 30365523 30365523 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 95 220 0 ENST00000305596.3:c.199G>A p.Ala67Thr p.A67T ENST00000305596 NM_006110.2 67 Gcc/Acc 0 +CD300E UCSF GRCh37 17 72608796 72608796 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 43 96 0 ENST00000328630.3:c.614G>A p.Arg205Lys p.R205K ENST00000328630 205 aGa/aAa 0 +CD300LD UCSF GRCh37 17 72584665 72584665 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 112 75 166 0 ENST00000375352.1:c.364G>A p.Val122Met p.V122M ENST00000375352 NM_001115152.1 122 Gtg/Atg 0 +CD40 UCSF GRCh37 20 44750474 44750474 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 74 247 0 ENST00000372285.3:c.67C>T p.Pro23Ser p.P23S ENST00000372285 NM_001250.4 23 Ccc/Tcc 0 +CD5 UCSF GRCh37 11 60889194 60889194 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 38 86 0 ENST00000347785.3:c.917C>T p.Ala306Val p.A306V ENST00000347785 NM_014207.3 306 gCc/gTc 0 +CD6 UCSF GRCh37 11 60786787 60786787 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 11 56 0 ENST00000313421.7:c.2004C>T p.Ala668= p.A668= ENST00000313421 NM_006725.4 668 gcC/gcT 0 +CD79B UCSF GRCh37 17 62007564 62007564 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 51 107 0 ENST00000392795.3:c.303G>A p.Gln101= p.Q101= ENST00000392795 NM_001039933.1 101 caG/caA 0 +CD83 UCSF GRCh37 6 14118245 14118245 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 36 13 56 0 ENST00000379153.3:c.102C>T p.Pro34= p.P34= ENST00000379153 NM_001040280.1 34 ccC/ccT 0 +CD86 UCSF GRCh37 3 121836932 121836932 + synonymous_variant Silent SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 52 128 0 ENST00000330540.2:c.885C>A p.Thr295= p.T295= ENST00000330540 NM_175862.4 295 acC/acA 0 +CD8A UCSF GRCh37 2 87013087 87013087 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 78 196 0 ENST00000409511.2:c.664G>A p.Val222Ile p.V222I ENST00000409511 NM_001145873.1 222 Gtc/Atc 0 +CDADC1 UCSF GRCh37 13 49833592 49833592 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 161 77 231 0 ENST00000251108.6:c.363G>A p.Arg121= p.R121= ENST00000251108 NM_001193478.1 121 agG/agA 0 +CDADC1 UCSF GRCh37 13 49841626 49841626 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 49 125 0 ENST00000251108.6:c.431C>T p.Ala144Val p.A144V ENST00000251108 NM_001193478.1 144 gCt/gTt 0 +CDC16 UCSF GRCh37 13 115024859 115024859 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 43 141 0 ENST00000360383.3:c.1300G>A p.Ala434Thr p.A434T ENST00000360383 NM_001078645.1 434 Gca/Aca 0 +CDC23 UCSF GRCh37 5 137534175 137534175 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 49 147 0 ENST00000394886.2:c.870G>A p.Arg290= p.R290= ENST00000394886 NM_004661.3 290 agG/agA 0 +CDC34 UCSF GRCh37 19 537137 537137 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 27 69 0 ENST00000215574.4:c.487G>A p.Asp163Asn p.D163N ENST00000215574 NM_004359.1 163 Gac/Aac 0 +CDC7 UCSF GRCh37 1 91973874 91973874 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 38 66 0 ENST00000428239.1:c.255G>A p.Glu85= p.E85= ENST00000428239 NM_001134420.1 85 gaG/gaA 0 +CDC7 UCSF GRCh37 1 91977338 91977338 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 68 139 0 ENST00000428239.1:c.430G>A p.Asp144Asn p.D144N ENST00000428239 NM_001134420.1 144 Gac/Aac 0 +CDCA4 UCSF GRCh37 14 105478160 105478160 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 65 170 0 ENST00000336219.3:c.107C>T p.Ser36Leu p.S36L ENST00000336219 NM_017955.3 36 tCg/tTg 0 +CDH2 UCSF GRCh37 18 25583066 25583066 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 73 183 0 ENST00000269141.3:c.915G>A p.Arg305= p.R305= ENST00000269141 NM_001792.3 305 agG/agA 0 +CDH2 UCSF GRCh37 18 25570165 25570165 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 69 203 0 ENST00000269141.3:c.1494C>T p.Ala498= p.A498= ENST00000269141 NM_001792.3 498 gcC/gcT 0 +CDH23 UCSF GRCh37 10 73556947 73556947 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 46 113 0 ENST00000398788.3:c.79C>T p.Leu27= p.L27= ENST00000398788 NM_001171933.1 27 Cta/Tta 0 +CDH23 UCSF GRCh37 10 73437387 73437387 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 39 92 0 ENST00000224721.6:c.1704G>A p.Lys568= p.K568= ENST00000224721 NM_022124.5 568 aaG/aaA 0 +CDH23 UCSF GRCh37 10 73498296 73498296 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 106 178 0 ENST00000224721.6:c.4266G>A p.Arg1422= p.R1422= ENST00000224721 NM_022124.5 1422 cgG/cgA 0 +CDIPT UCSF GRCh37 16 29872497 29872497 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 49 136 0 ENST00000219789.6:c.262C>T p.Pro88Ser p.P88S ENST00000219789 NM_006319.3 88 Cct/Tct 0 +CDK12 UCSF GRCh37 17 37676277 37676277 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 140 89 203 0 ENST00000447079.4:c.3032C>T p.Ala1011Val p.A1011V ENST00000447079 NM_015083.1 1011 gCt/gTt 0 +CDK5 UCSF GRCh37 7 150754902 150754902 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 29 96 0 ENST00000485972.1:c.34G>A p.Glu12Lys p.E12K ENST00000485972 NM_004935.3 12 Gaa/Aaa 0 +CDRT1 UCSF GRCh37 17 15522780 15522780 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 235 133 468 0 ENST00000395906.3:c.47G>A p.Cys16Tyr p.C16Y ENST00000395906 NM_006382.3 16 tGt/tAt 0 +CDRT1 UCSF GRCh37 17 15496780 15496780 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 228 170 349 0 ENST00000395906.3:c.1877T>A p.Leu626His p.L626H ENST00000395906 NM_006382.3 626 cTc/cAc 0 +CEACAM20 UCSF GRCh37 19 45021256 45021256 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 53 146 0 ENST00000454753.1:n.1339G>A *447* ENST00000454753 0 +CEACAM21 UCSF GRCh37 19 42092212 42092212 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 44 113 0 ENST00000401445.2:c.870C>T p.Ser290= p.S290= ENST00000401445 290 agC/agT 0 +CELSR3 UCSF GRCh37 3 48684203 48684203 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 27 59 0 ENST00000164024.4:c.7288G>A p.Gly2430Ser p.G2430S ENST00000164024 NM_001407.2 2430 Ggt/Agt 0 +CELSR3 UCSF GRCh37 3 48697265 48697265 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 63 142 0 ENST00000164024.4:c.2803G>A p.Asp935Asn p.D935N ENST00000164024 NM_001407.2 935 Gac/Aac 0 +CELSR3 UCSF GRCh37 3 48698563 48698563 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 16 18 37 0 ENST00000164024.4:c.1505A>G p.Asp502Gly p.D502G ENST00000164024 NM_001407.2 502 gAc/gGc 0 +CEMP1 UCSF GRCh37 16 2580808 2580808 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 19 45 0 ENST00000382350.1:c.267G>A p.Gly89= p.G89= ENST00000382350 89 ggG/ggA 0 +CENPB UCSF GRCh37 20 3766747 3766747 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 26 37 0 ENST00000379751.4:c.384G>A p.Arg128= p.R128= ENST00000379751 NM_001810.5 128 cgG/cgA 0 +CENPE UCSF GRCh37 4 104066777 104066777 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 72 172 0 ENST00000265148.3:c.4475C>T p.Thr1492Ile p.T1492I ENST00000265148 NM_001813.2 1492 aCt/aTt 0 +CENPF UCSF GRCh37 1 214814907 214814907 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 81 199 0 ENST00000366955.3:c.3226G>A p.Glu1076Lys p.E1076K ENST00000366955 NM_016343.3 1076 Gaa/Aaa 0 +CENPT UCSF GRCh37 16 67862212 67862212 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 34 38 90 0 ENST00000562787.1:c.1644C>T p.Ile548= p.I548= ENST00000562787 NM_025082.3 548 atC/atT 0 +CEP112 UCSF GRCh37 17 64092721 64092721 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 41 97 0 ENST00000392769.2:c.672G>A p.Lys224= p.K224= ENST00000392769 NM_145036.3 224 aaG/aaA 0 +CEP135 UCSF GRCh37 4 56876058 56876058 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 115 104 176 0 ENST00000257287.4:c.2494A>G p.Arg832Gly p.R832G ENST00000257287 NM_025009.4 832 Aga/Gga 0 +CEP170 UCSF GRCh37 1 243327806 243327806 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 77 316 0 ENST00000366542.1:c.3456G>A p.Gln1152= p.Q1152= ENST00000366542 NM_014812.2 1152 caG/caA 0 +CEP192 UCSF GRCh37 18 13096183 13096183 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 65 145 0 ENST00000506447.1:c.6434G>A p.Cys2145Tyr p.C2145Y ENST00000506447 NM_032142.3 2145 tGt/tAt 0 +CEP290 UCSF GRCh37 12 88500814 88500814 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 64 155 0 ENST00000552810.1:c.2545G>A p.Asp849Asn p.D849N ENST00000552810 NM_025114.3 849 Gat/Aat 0 +CEP78 UCSF GRCh37 9 80881440 80881440 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 59 144 0 ENST00000376597.4:c.1931G>A p.Gly644Glu p.G644E ENST00000376597 NM_001098802.1 644 gGa/gAa 0 +CES3 UCSF GRCh37 16 67006937 67006937 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 52 106 0 ENST00000303334.4:c.1701C>T p.Ala567= p.A567= ENST00000303334 NM_024922.5 567 gcC/gcT 0 +CFHR3 UCSF GRCh37 1 196749019 196749019 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 68 137 0 ENST00000367425.4:c.346C>T p.Pro116Ser p.P116S ENST00000367425 NM_021023.5 116 Cct/Tct 0 +CHAF1A UCSF GRCh37 19 4423333 4423333 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 102 193 0 ENST00000301280.5:c.1249G>A p.Ala417Thr p.A417T ENST00000301280 NM_005483.2 417 Gct/Act 0 +CHAT UCSF GRCh37 10 50873074 50873074 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 69 156 0 ENST00000337653.2:c.2229C>T p.Ser743= p.S743= ENST00000337653 NM_020549.4 743 agC/agT 0 +CHD1L UCSF GRCh37 1 146765378 146765378 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 147 359 0 ENST00000369258.4:c.2478G>A p.Lys826= p.K826= ENST00000369258 NM_001256336.1 826 aaG/aaA 0 +CHD6 UCSF GRCh37 20 40065937 40065937 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 65 138 0 ENST00000373233.3:c.4045G>A p.Val1349Ile p.V1349I ENST00000373233 NM_032221.4 1349 Gta/Ata 0 +CHD6 UCSF GRCh37 20 40127937 40127937 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 22 55 0 ENST00000373233.3:c.913G>A p.Glu305Lys p.E305K ENST00000373233 NM_032221.4 305 Gag/Aag 0 +CHD9 UCSF GRCh37 16 53308204 53308204 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 169 128 237 0 ENST00000566029.1:c.4957G>A p.Val1653Ile p.V1653I ENST00000566029 1653 Gtt/Att 0 +CHI3L2 UCSF GRCh37 1 111781529 111781529 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 81 185 0 ENST00000445067.2:c.893C>T p.Ser298Phe p.S298F ENST00000445067 298 tCt/tTt 0 +CHIT1 UCSF GRCh37 1 203192374 203192374 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 79 175 0 ENST00000367229.1:c.494C>T p.Ala165Val p.A165V ENST00000367229 NM_003465.2 165 gCc/gTc 0 +CHPF2 UCSF GRCh37 7 150934555 150934555 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 49 111 0 ENST00000035307.2:c.1107C>T p.Arg369= p.R369= ENST00000035307 NM_019015.1 369 cgC/cgT 0 +CHRM1 UCSF GRCh37 11 62677564 62677564 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 59 143 0 ENST00000306960.3:c.1009G>A p.Ala337Thr p.A337T ENST00000306960 NM_000738.2 337 Gct/Act 0 +CHRM2 UCSF GRCh37 7 136700241 136700241 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 65 113 0 ENST00000445907.2:c.629C>T p.Ser210Phe p.S210F ENST00000445907 NM_001006627.1 210 tCc/tTc 0 +CHST11 UCSF GRCh37 12 105150931 105150931 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 45 114 0 ENST00000303694.5:c.409G>A p.Val137Ile p.V137I ENST00000303694 NM_018413.5 137 Gtc/Atc 0 +CHST12 UCSF GRCh37 7 2472470 2472470 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 55 95 0 ENST00000258711.6:c.196G>A p.Val66Ile p.V66I ENST00000258711 NM_001243794.1 66 Gtc/Atc 0 +CHST13 UCSF GRCh37 3 126260857 126260857 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.014,1000g2011may_all_0.0310,snp132_rs58576050 P18_Rec Untested WXS Illumina HiSeq 13 15 25 0 ENST00000319340.2:c.462C>T p.Asp154= p.D154= ENST00000319340 NM_152889.2 154 gaC/gaT 0 +CHST4 UCSF GRCh37 16 71570604 71570604 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 93 171 0 ENST00000338482.5:c.24G>A p.Lys8= p.K8= ENST00000338482 8 aaG/aaA 0 +CHST5 UCSF GRCh37 16 75564161 75564161 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 17 28 0 ENST00000336257.3:c.122C>T p.Thr41Ile p.T41I ENST00000336257 NM_024533.4 41 aCc/aTc 0 +CIT UCSF GRCh37 12 120295477 120295477 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 156 103 248 0 ENST00000392521.2:c.264G>A p.Gln88= p.Q88= ENST00000392521 NM_001206999.1 88 caG/caA 0 +CITED2 UCSF GRCh37 6 139695002 139695002 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 12 34 0 ENST00000367651.2:c.80G>A p.Arg27His p.R27H ENST00000367651 NM_006079.4 27 cGc/cAc 0 +CKAP2 UCSF GRCh37 13 53039430 53039430 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 76 197 0 ENST00000378037.5:c.1309G>A p.Gly437Arg p.G437R ENST00000378037 NM_018204.3 437 Gga/Aga 0 +CKAP5 UCSF GRCh37 11 46819722 46819722 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 144 109 202 0 ENST00000529230.1:c.1084G>A p.Val362Ile p.V362I ENST00000529230 362 Gtt/Att 0 +CKMT2 UCSF GRCh37 5 80555039 80555039 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 45 110 0 ENST00000424301.2:c.980C>T p.Ala327Val p.A327V ENST00000424301 NM_001825.2 327 gCt/gTt 0 +CLCN1 UCSF GRCh37 7 143043243 143043243 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 41 85 0 ENST00000343257.2:c.2183C>T p.Ser728Phe p.S728F ENST00000343257 NM_000083.2 728 tCc/tTc 0 +CLCN2 UCSF GRCh37 3 184076576 184076576 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 22 39 0 ENST00000265593.4:c.246C>T p.Phe82= p.F82= ENST00000265593 NM_004366.5 82 ttC/ttT 0 +CLCN3 UCSF GRCh37 4 170613362 170613362 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 159 136 274 0 ENST00000347613.4:c.827G>A p.Gly276Asp p.G276D ENST00000347613 NM_173872.3 276 gGt/gAt 0 +CLCN7 UCSF GRCh37 16 1500513 1500513 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 5 20 0 ENST00000382745.4:c.1602C>T p.Tyr534= p.Y534= ENST00000382745 NM_001287.5 534 taC/taT 0 +CLDN1 UCSF GRCh37 3 190030796 190030796 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 188 132 269 0 ENST00000295522.3:c.253G>A p.Val85Met p.V85M ENST00000295522 NM_021101.4 85 Gtg/Atg 0 +CLEC9A UCSF GRCh37 12 10217414 10217414 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 76 165 0 ENST00000355819.1:c.555C>T p.Arg185= p.R185= ENST00000355819 NM_207345.2 185 cgC/cgT 0 +CLINT1 UCSF GRCh37 5 157221923 157221923 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 31 91 0 ENST00000523908.1:c.1070G>A p.Gly357Asp p.G357D ENST00000523908 357 gGc/gAc 0 +CLIP1 UCSF GRCh37 12 122862435 122862435 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 200 147 277 0 ENST00000540338.1:c.158A>G p.Glu53Gly p.E53G ENST00000540338 53 gAa/gGa 0 +CLMP UCSF GRCh37 11 122968596 122968596 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 86 167 0 ENST00000448775.2:c.93C>T p.Val31= p.V31= ENST00000448775 NM_024769.2 31 gtC/gtT 0 +CLSTN2 UCSF GRCh37 3 140280982 140280982 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 52 136 0 ENST00000458420.3:c.2044C>T p.Pro682Ser p.P682S ENST00000458420 NM_022131.2 682 Ccc/Tcc 0 +CLVS2 UCSF GRCh37 6 123318973 123318973 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 52 162 0 ENST00000275162.5:c.51C>T p.Arg17= p.R17= ENST00000275162 NM_001010852.3 17 cgC/cgT 0 +CMTM4 UCSF GRCh37 16 66651192 66651192 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 48 68 0 ENST00000330687.4:c.693G>A p.Trp231Ter p.W231* ENST00000330687 NM_181521.2 231 tgG/tgA 0 +CMYA5 UCSF GRCh37 5 79035216 79035216 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 62 141 0 ENST00000446378.2:c.10628G>A p.Ser3543Asn p.S3543N ENST00000446378 NM_153610.3 3543 aGt/aAt 0 +CMYA5 UCSF GRCh37 5 79041083 79041083 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 104 216 0 ENST00000446378.2:c.10773G>A p.Gln3591= p.Q3591= ENST00000446378 NM_153610.3 3591 caG/caA 0 +CNGB1 UCSF GRCh37 16 57954336 57954336 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 52 129 0 ENST00000251102.8:c.1756C>T p.Leu586Phe p.L586F ENST00000251102 NM_001297.4 586 Ctc/Ttc 0 +CNKSR1 UCSF GRCh37 1 26510770 26510770 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 92 155 0 ENST00000361530.6:c.992C>T p.Ala331Val p.A331V ENST00000361530 331 gCc/gTc 0 +CNNM4 UCSF GRCh37 2 97475190 97475190 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 49 102 0 ENST00000377075.2:c.2264C>T p.Thr755Ile p.T755I ENST00000377075 NM_020184.3 755 aCc/aTc 0 +CNNM4 UCSF GRCh37 2 97427097 97427097 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 70 164 0 ENST00000377075.2:c.361G>A p.Val121Ile p.V121I ENST00000377075 NM_020184.3 121 Gtc/Atc 0 +CNTN3 UCSF GRCh37 3 74349022 74349022 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 42 133 0 ENST00000263665.6:c.2163G>A p.Trp721Ter p.W721* ENST00000263665 NM_020872.1 721 tgG/tgA 0 +CNTNAP4 UCSF GRCh37 16 76389299 76389299 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 92 75 159 0 ENST00000478060.1:c.206T>C p.Val69Ala p.V69A ENST00000478060 NM_138994.3 69 gTg/gCg 0 +CNTRL UCSF GRCh37 9 123886221 123886221 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 119 143 0 ENST00000373855.1:c.1663G>A p.Ala555Thr p.A555T ENST00000373855 555 Gct/Act 0 +CNTROB UCSF GRCh37 17 7837463 7837463 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 73 175 0 ENST00000380262.3:c.278C>T p.Ser93Phe p.S93F ENST00000380262 NM_001037144.5 93 tCt/tTt 0 +CNTROB UCSF GRCh37 17 7847867 7847867 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 56 89 0 ENST00000380262.3:c.1645C>T p.Leu549= p.L549= ENST00000380262 NM_001037144.5 549 Ctg/Ttg 0 +COIL UCSF GRCh37 17 55027908 55027908 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 109 212 0 ENST00000240316.4:c.695G>A p.Arg232Lys p.R232K ENST00000240316 NM_004645.2 232 aGg/aAg 0 +COL16A1 UCSF GRCh37 1 32122668 32122668 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 69 126 0 ENST00000373672.3:c.4022G>A p.Gly1341Asp p.G1341D ENST00000373672 NM_001856.3 1341 gGc/gAc 0 +COL17A1 UCSF GRCh37 10 105824195 105824195 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 29 49 0 ENST00000353479.5:c.766+1G>A p.X256_splice ENST00000353479 NM_000494.3 0 +COL20A1 UCSF GRCh37 20 61951530 61951530 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 46 0 ENST00000358894.6:c.3056C>T p.Pro1019Leu p.P1019L ENST00000358894 NM_020882.2 1019 cCc/cTc 0 +COL20A1 UCSF GRCh37 20 61959774 61959774 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 40 71 0 ENST00000358894.6:c.3705G>A p.Leu1235= p.L1235= ENST00000358894 NM_020882.2 1235 ctG/ctA 0 +COL21A1 UCSF GRCh37 6 55989066 55989066 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 86 92 139 0 ENST00000244728.5:c.1675G>A p.Ala559Thr p.A559T ENST00000244728 NM_030820.3 559 Gct/Act 0 +COL21A1 UCSF GRCh37 6 56031718 56031718 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 67 154 0 ENST00000244728.5:c.1264G>A p.Glu422Lys p.E422K ENST00000244728 NM_030820.3 422 Gag/Aag 0 +COL22A1 UCSF GRCh37 8 139606353 139606353 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 30 95 0 ENST00000303045.6:c.4522G>A p.Asp1508Asn p.D1508N ENST00000303045 NM_152888.1 1508 Gat/Aat 0 +COL22A1 UCSF GRCh37 8 139661982 139661982 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 34 65 0 ENST00000303045.6:c.3373C>T p.Pro1125Ser p.P1125S ENST00000303045 NM_152888.1 1125 Cct/Tct 0 +COL28A1 UCSF GRCh37 7 7410432 7410432 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 70 159 0 ENST00000399429.3:c.2990C>T p.Pro997Leu p.P997L ENST00000399429 NM_001037763.2 997 cCt/cTt 0 +COL28A1 UCSF GRCh37 7 7477036 7477036 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 29 60 0 ENST00000399429.3:c.1780C>T p.Pro594Ser p.P594S ENST00000399429 NM_001037763.2 594 Cct/Tct 0 +COL3A1 UCSF GRCh37 2 189864614 189864614 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 3 11 0 ENST00000304636.3:c.2276G>A p.Gly759Asp p.G759D ENST00000304636 NM_000090.3 759 gGc/gAc 0 +COL4A1 UCSF GRCh37 13 110815821 110815821 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 15 69 0 ENST00000375820.4:c.4238C>T p.Ala1413Val p.A1413V ENST00000375820 NM_001845.4 1413 gCc/gTc 0 +COL4A2 UCSF GRCh37 13 111102651 111102651 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 42 95 0 ENST00000360467.5:c.1190-1G>A p.X397_splice ENST00000360467 NM_001846.2 0 +COL5A2 UCSF GRCh37 2 189927939 189927939 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 72 145 0 ENST00000374866.3:c.1828C>T p.Gln610Ter p.Q610* ENST00000374866 NM_000393.3 610 Cag/Tag 0 +COL6A3 UCSF GRCh37 2 238290014 238290014 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 75 192 1 ENST00000295550.4:c.1441C>T p.Leu481Phe p.L481F ENST00000295550 NM_004369.3 481 Ctt/Ttt 0 +COL7A1 UCSF GRCh37 3 48619761 48619761 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 60 148 0 ENST00000328333.8:c.4630G>A p.Val1544Met p.V1544M ENST00000328333 NM_000094.3 1544 Gtg/Atg 0 +COL8A1 UCSF GRCh37 3 99514361 99514361 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 6 24 0 ENST00000261037.3:c.1616G>A p.Gly539Glu p.G539E ENST00000261037 NM_001850.4 539 gGa/gAa 0 +COL8A2 UCSF GRCh37 1 36564612 36564612 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 28 60 0 ENST00000397799.1:c.670G>A p.Ala224Thr p.A224T ENST00000397799 224 Gcc/Acc 0 +COMP UCSF GRCh37 19 18896951 18896951 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 68 115 0 ENST00000222271.2:c.1313G>A p.Gly438Glu p.G438E ENST00000222271 NM_000095.2 438 gGa/gAa 0 +COPS3 UCSF GRCh37 17 17171289 17171289 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 75 116 0 ENST00000268717.5:c.351C>T p.Pro117= p.P117= ENST00000268717 NM_003653.3 117 ccC/ccT 0 +COPS4 UCSF GRCh37 4 83971051 83971051 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 122 91 247 0 ENST00000264389.2:c.324G>A p.Gln108= p.Q108= ENST00000264389 NM_016129.2 108 caG/caA 0 +CORO7 UCSF GRCh37 16 4414887 4414887 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 10 28 0 ENST00000251166.4:c.933G>A p.Gly311= p.G311= ENST00000251166 NM_024535.4 311 ggG/ggA 0 +CPA2 UCSF GRCh37 7 129909590 129909590 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 139 147 0 ENST00000222481.4:c.235G>A p.Val79Met p.V79M ENST00000222481 NM_001869.2 79 Gtg/Atg 0 +CPA4 UCSF GRCh37 7 129939224 129939224 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 132 130 0 ENST00000222482.4:c.265G>A p.Val89Met p.V89M ENST00000222482 NM_016352.3 89 Gtg/Atg 0 +CPEB4 UCSF GRCh37 5 173372078 173372078 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 126 227 0 ENST00000265085.5:c.1391G>A p.Gly464Glu p.G464E ENST00000265085 NM_030627.2 464 gGg/gAg 0 +CPLX3 UCSF GRCh37 15 75120402 75120402 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 11 40 0 ENST00000395018.4:c.192G>A p.Gln64= p.Q64= ENST00000395018 NM_001030005.2 64 caG/caA 0 +CPNE8 UCSF GRCh37 12 39087557 39087557 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 85 202 0 ENST00000331366.5:c.1045G>A p.Glu349Lys p.E349K ENST00000331366 NM_153634.2 349 Gaa/Aaa 0 +CPNE8 UCSF GRCh37 12 39069519 39069519 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 49 101 0 ENST00000331366.5:c.1432G>A p.Ala478Thr p.A478T ENST00000331366 NM_153634.2 478 Gca/Aca 0 +CRAT UCSF GRCh37 9 131864202 131864202 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 48 107 0 ENST00000318080.2:c.765C>T p.His255= p.H255= ENST00000318080 NM_001257363.1 255 caC/caT 0 +CREB1 UCSF GRCh37 2 208420369 208420369 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 43 80 0 ENST00000432329.2:c.10G>A p.Glu4Lys p.E4K ENST00000432329 NM_134442.3 4 Gaa/Aaa 0 +CREB3L2 UCSF GRCh37 7 137569861 137569861 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 77 53 103 0 ENST00000330387.6:c.1150G>A p.Val384Met p.V384M ENST00000330387 NM_194071.3 384 Gtg/Atg 0 +CREBBP UCSF GRCh37 16 3778942 3778942 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 17 15 0 ENST00000262367.5:c.6106C>T p.Pro2036Ser p.P2036S ENST00000262367 NM_004380.2 2036 Ccc/Tcc 0 +CRELD1 UCSF GRCh37 3 9976276 9976276 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 25 95 0 ENST00000326434.5:c.154C>T p.Leu52= p.L52= ENST00000326434 NM_001031717.3 52 Ctg/Ttg 0 +CRHBP UCSF GRCh37 5 76264612 76264612 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 84 171 0 ENST00000274368.4:c.871G>A p.Val291Ile p.V291I ENST00000274368 NM_001882.3 291 Gta/Ata 0 +CRLF1 UCSF GRCh37 19 18709378 18709378 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 38 132 0 ENST00000392386.3:c.561C>T p.Tyr187= p.Y187= ENST00000392386 NM_004750.4 187 taC/taT 0 +CROCC UCSF GRCh37 1 17292500 17292500 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 35 79 0 ENST00000375541.5:c.4582C>T p.Leu1528Phe p.L1528F ENST00000375541 NM_014675.3 1528 Ctt/Ttt 0 +CSE1L UCSF GRCh37 20 47688968 47688968 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 117 79 196 0 ENST00000262982.2:c.914G>A p.Gly305Asp p.G305D ENST00000262982 NM_001316.3 305 gGt/gAt 0 +CSF1R UCSF GRCh37 5 149434822 149434822 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 46 89 0 ENST00000286301.3:c.2632C>T p.Pro878Ser p.P878S ENST00000286301 NM_005211.3 878 Cct/Tct 0 +CSF3R UCSF GRCh37 1 36932337 36932337 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 60 130 0 ENST00000361632.4:c.2132C>T p.Ser711Phe p.S711F ENST00000361632 711 tCc/tTc 0 +CSF3R UCSF GRCh37 1 36934774 36934774 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 45 74 0 ENST00000361632.4:c.1559C>T p.Ala520Val p.A520V ENST00000361632 520 gCc/gTc 0 +CSF3R UCSF GRCh37 1 36933197 36933197 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 28 48 0 ENST00000361632.4:c.1920C>T p.Thr640= p.T640= ENST00000361632 640 acC/acT 0 +CSNK1A1 UCSF GRCh37 5 148897381 148897381 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 116 236 0 ENST00000515768.1:c.516C>T p.Asp172= p.D172= ENST00000515768 172 gaC/gaT 0 +CSPG4 UCSF GRCh37 15 75977233 75977233 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 71 181 0 ENST00000308508.5:c.4293C>T p.Arg1431= p.R1431= ENST00000308508 NM_001897.4 1431 cgC/cgT 0 +CST7 UCSF GRCh37 20 24937999 24937999 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 164 110 267 0 ENST00000480798.1:c.147C>T p.Val49= p.V49= ENST00000480798 NM_003650.3 49 gtC/gtT 0 +CSTF2 UCSF GRCh37 X 100079185 100079185 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 68 85 0 ENST00000372972.2:c.641G>A p.Gly214Asp p.G214D ENST00000372972 NM_001325.2 214 gGc/gAc 0 +CTIF UCSF GRCh37 18 46284610 46284610 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 93 160 1 ENST00000382998.4:c.905C>T p.Thr302Ile p.T302I ENST00000382998 NM_001142397.1 302 aCc/aTc 0 +CTNNAL1 UCSF GRCh37 9 111705072 111705072 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 80 173 0 ENST00000325551.4:c.2182G>A p.Asp728Asn p.D728N ENST00000325551 NM_003798.2 728 Gac/Aac 0 +CTSA UCSF GRCh37 20 44520380 44520380 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 87 147 0 ENST00000372484.3:c.227G>A p.Gly76Asp p.G76D ENST00000372484 NM_000308.2 76 gGc/gAc 0 +CTSC UCSF GRCh37 11 88068104 88068104 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 56 130 0 ENST00000227266.5:c.318+1G>A p.X106_splice ENST00000227266 NM_001814.4 0 +CTSL2 UCSF GRCh37 9 99795242 99795242 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 46 96 0 ENST00000259470.5:c.994C>T p.Pro332Ser p.P332S ENST00000259470 NM_001333.3 332 Ccc/Tcc 0 +CUBN UCSF GRCh37 10 16870808 16870808 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 87 133 0 ENST00000377833.4:c.10760G>A p.Gly3587Glu p.G3587E ENST00000377833 NM_001081.3 3587 gGa/gAa 0 +CUBN UCSF GRCh37 10 16962047 16962047 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 38 116 0 ENST00000377833.4:c.6736G>A p.Asp2246Asn p.D2246N ENST00000377833 NM_001081.3 2246 Gat/Aat 0 +CUBN UCSF GRCh37 10 17145230 17145230 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 159 54 101 0 ENST00000377833.4:c.1424G>A p.Gly475Glu p.G475E ENST00000377833 NM_001081.3 475 gGa/gAa 0 +CUL1 UCSF GRCh37 7 148480875 148480875 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 80 154 0 ENST00000325222.4:c.1084G>A p.Asp362Asn p.D362N ENST00000325222 NM_003592.2 362 Gac/Aac 0 +CUL3 UCSF GRCh37 2 225339030 225339030 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 64 164 0 ENST00000264414.4:c.2239G>A p.Gly747Arg p.G747R ENST00000264414 NM_003590.4 747 Gga/Aga 0 +CUL3 UCSF GRCh37 2 225342968 225342968 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 83 135 0 ENST00000264414.4:c.2124G>A p.Val708= p.V708= ENST00000264414 NM_003590.4 708 gtG/gtA 0 +CXCL1 UCSF GRCh37 4 74735207 74735207 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 8 18 0 ENST00000395761.3:c.20C>T p.Ser7Phe p.S7F ENST00000395761 NM_001511.3 7 tCc/tTc 0 +CXCL11 UCSF GRCh37 4 76957089 76957089 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 97 185 0 ENST00000306621.3:c.52G>A p.Val18Ile p.V18I ENST00000306621 NM_005409.4 18 Gtt/Att 0 +CYB561D2 UCSF GRCh37 3 50390813 50390813 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 42 127 0 ENST00000418577.1:c.307C>T p.Leu103Phe p.L103F ENST00000418577 103 Ctt/Ttt 0 +CYB5R1 UCSF GRCh37 1 202931800 202931800 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 52 105 0 ENST00000367249.4:c.773C>T p.Thr258Ile p.T258I ENST00000367249 NM_016243.2 258 aCt/aTt 0 +CYFIP2 UCSF GRCh37 5 156787375 156787375 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 93 230 0 ENST00000521420.1:c.2825C>T p.Ser942Phe p.S942F ENST00000521420 942 tCc/tTc 0 +CYP2C19 UCSF GRCh37 10 96522537 96522537 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 133 261 0 ENST00000371321.3:c.75G>A p.Gly25= p.G25= ENST00000371321 NM_000769.1 25 ggG/ggA 0 +CYP2D6 UCSF GRCh37 22 42523985 42523985 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 41 111 0 ENST00000360608.5:c.844G>A p.Ala282Thr p.A282T ENST00000360608 NM_000106.5 282 Gcc/Acc 0 +CYP2W1 UCSF GRCh37 7 1028323 1028323 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 16 28 0 ENST00000308919.7:c.1338G>A p.Leu446= p.L446= ENST00000308919 NM_017781.2 446 ctG/ctA 0 +CYP4A11 UCSF GRCh37 1 47398447 47398447 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 251 169 337 0 ENST00000310638.4:c.1350C>T p.Phe450= p.F450= ENST00000310638 NM_000778.3 450 ttC/ttT 0 +CYP4B1 UCSF GRCh37 1 47283665 47283665 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 107 224 0 ENST00000371923.4:c.1236C>T p.Ala412= p.A412= ENST00000371923 NM_001099772.1 412 gcC/gcT 0 +DAB2IP UCSF GRCh37 9 124535010 124535010 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 46 77 0 ENST00000259371.2:c.2119C>T p.Pro707Ser p.P707S ENST00000259371 NM_032552.2 707 Cct/Tct 0 +DACH1 UCSF GRCh37 13 72440792 72440792 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 24 0 ENST00000305425.4:c.116C>T p.Ser39Phe p.S39F ENST00000305425 NM_080759.4 39 tCt/tTt 0 +DACT1 UCSF GRCh37 14 59107532 59107532 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 157 120 255 0 ENST00000335867.4:c.424G>A p.Asp142Asn p.D142N ENST00000335867 142 Gat/Aat 0 +DAG1 UCSF GRCh37 3 49568292 49568292 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 50 86 0 ENST00000545947.1:c.348C>T p.Thr116= p.T116= ENST00000545947 NM_001177634.2 116 acC/acT 0 +DAG1 UCSF GRCh37 3 49548030 49548030 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 62 114 0 ENST00000545947.1:c.63G>A p.Leu21= p.L21= ENST00000545947 NM_001177634.2 21 ctG/ctA 0 +DAO UCSF GRCh37 12 109294270 109294270 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 80 163 0 ENST00000228476.3:c.1003G>A p.Glu335Lys p.E335K ENST00000228476 NM_001917.4 335 Gaa/Aaa 0 +DAPK1 UCSF GRCh37 9 90263709 90263709 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 65 168 0 ENST00000408954.3:c.1343C>T p.Ala448Val p.A448V ENST00000408954 NM_004938.2 448 gCc/gTc 0 +DAXX UCSF GRCh37 6 33288940 33288940 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 24 55 0 ENST00000374542.5:c.612G>A p.Arg204= p.R204= ENST00000374542 NM_001141970.1 204 cgG/cgA 0 +DAXX UCSF GRCh37 6 33287477 33287477 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 74 178 0 ENST00000374542.5:c.1620C>T p.Pro540= p.P540= ENST00000374542 NM_001141970.1 540 ccC/ccT 0 +DCAF11 UCSF GRCh37 14 24592253 24592253 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 58 115 0 ENST00000446197.3:c.1473G>A p.Trp491Ter p.W491* ENST00000446197 NM_025230.4 491 tgG/tgA 0 +DCAF4 UCSF GRCh37 14 73422231 73422231 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 116 232 0 ENST00000358377.2:c.1006G>A p.Ala336Thr p.A336T ENST00000358377 NM_001163509.1 336 Gct/Act 0 +DCAF4L1 UCSF GRCh37 4 41984708 41984708 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 93 206 0 ENST00000333141.5:c.899G>A p.Arg300Lys p.R300K ENST00000333141 NM_001029955.3 300 aGg/aAg 0 +DCAF5 UCSF GRCh37 14 69589060 69589060 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 53 136 0 ENST00000341516.5:c.232G>A p.Val78Ile p.V78I ENST00000341516 NM_003861.2 78 Gtt/Att 0 +DCBLD2 UCSF GRCh37 3 98518407 98518407 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 210 118 333 0 ENST00000326840.6:c.2137G>A p.Gly713Arg p.G713R ENST00000326840 NM_080927.3 713 Gga/Aga 0 +DCC UCSF GRCh37 18 50923802 50923802 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 70 149 0 ENST00000442544.2:c.2813C>T p.Thr938Ile p.T938I ENST00000442544 NM_005215.3 938 aCc/aTc 0 +DCDC5 UCSF GRCh37 11 30946895 30946895 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 185 129 290 0 ENST00000339794.5:c.195G>A p.Lys65= p.K65= ENST00000339794 65 aaG/aaA 0 +DCHS2 UCSF GRCh37 4 155156392 155156392 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 54 137 0 ENST00000357232.4:c.8047G>A p.Asp2683Asn p.D2683N ENST00000357232 NM_017639.3 2683 Gac/Aac 0 +DCHS2 UCSF GRCh37 4 155411228 155411228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 16 35 0 ENST00000339452.1:c.1280C>T p.Ser427Phe p.S427F ENST00000339452 NM_001142552.1 427 tCt/tTt 0 +DCLK2 UCSF GRCh37 4 151114344 151114344 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 90 225 0 ENST00000302176.8:c.811C>T p.Pro271Ser p.P271S ENST00000302176 NM_001040261.4 271 Cca/Tca 0 +DCLK2 UCSF GRCh37 4 151023922 151023922 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 59 171 0 ENST00000302176.8:c.714C>T p.Asp238= p.D238= ENST00000302176 NM_001040261.4 238 gaC/gaT 0 +DCLRE1A UCSF GRCh37 10 115608882 115608882 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 223 179 387 0 ENST00000361384.2:c.1982C>T p.Ser661Phe p.S661F ENST00000361384 NM_014881.4 661 tCt/tTt 0 +DCTN4 UCSF GRCh37 5 150133040 150133040 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 35 72 0 ENST00000446090.2:c.385+1G>A p.X129_splice ENST00000446090 NM_001135643.1 0 +DDX17 UCSF GRCh37 22 38881953 38881953 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 64 94 0 ENST00000396821.3:c.2183C>T p.Pro728Leu p.P728L ENST00000396821 NM_006386.4 728 cCt/cTt 0 +DDX24 UCSF GRCh37 14 94528656 94528656 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 171 132 236 0 ENST00000330836.5:c.1030C>T p.Leu344= p.L344= ENST00000330836 NM_020414.3 344 Ctg/Ttg 0 +DDX28 UCSF GRCh37 16 68056152 68056152 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 101 181 0 ENST00000332395.5:c.954C>T p.Asp318= p.D318= ENST00000332395 NM_018380.3 318 gaC/gaT 0 +DDX41 UCSF GRCh37 5 176941964 176941964 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 48 78 0 ENST00000507955.1:c.751C>T p.Pro251Ser p.P251S ENST00000507955 NM_016222.2 251 Ccc/Tcc 0 +DDX60 UCSF GRCh37 4 169206643 169206643 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 34 67 0 ENST00000393743.3:c.1346C>T p.Ser449Phe p.S449F ENST00000393743 NM_017631.5 449 tCc/tTc 0 +DDX60L UCSF GRCh37 4 169343778 169343778 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 67 116 0 ENST00000260184.7:c.2141G>A p.Gly714Glu p.G714E ENST00000260184 NM_001012967.1 714 gGa/gAa 0 +DEC1 UCSF GRCh37 9 118163567 118163567 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 64 147 0 ENST00000374016.1:c.183G>A p.Arg61= p.R61= ENST00000374016 NM_017418.2 61 agG/agA 0 +DEDD2 UCSF GRCh37 19 42703731 42703731 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 35 70 0 ENST00000595337.1:c.840G>A p.Leu280= p.L280= ENST00000595337 NM_001270614.1 280 ctG/ctA 0 +DEFA6 UCSF GRCh37 8 6783437 6783437 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 24 63 0 ENST00000297436.2:c.121C>T p.Gln41Ter p.Q41* ENST00000297436 NM_001926.3 41 Cag/Tag 0 +DEFB115 UCSF GRCh37 20 29845509 29845509 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 56 138 0 ENST00000400552.1:c.43C>T p.Leu15Phe p.L15F ENST00000400552 NM_001037730.1 15 Ctc/Ttc 0 +DENND3 UCSF GRCh37 8 142146891 142146891 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 22 0 ENST00000262585.2:c.145+1G>A p.X49_splice ENST00000262585 NM_014957.2 0 +DENND3 UCSF GRCh37 8 142165968 142165968 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 104 203 0 ENST00000262585.2:c.855G>A p.Leu285= p.L285= ENST00000262585 NM_014957.2 285 ctG/ctA 0 +DENND4B UCSF GRCh37 1 153915483 153915483 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 49 112 0 ENST00000361217.4:c.441C>T p.Tyr147= p.Y147= ENST00000361217 NM_014856.2 147 taC/taT 0 +DEPDC1B UCSF GRCh37 5 59943252 59943252 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 51 118 0 ENST00000265036.5:c.423G>A p.Glu141= p.E141= ENST00000265036 NM_018369.2 141 gaG/gaA 0 +DGKH UCSF GRCh37 13 42772728 42772728 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 69 164 0 ENST00000337343.4:c.2282C>T p.Ser761Phe p.S761F ENST00000337343 NM_178009.3 761 tCc/tTc 0 +DHRS3 UCSF GRCh37 1 12640563 12640563 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 48 104 0 ENST00000376223.2:c.327C>T p.Ala109= p.A109= ENST00000376223 NM_004753.4 109 gcC/gcT 0 +DHRS4 UCSF GRCh37 14 24429110 24429110 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 250 92 339 0 ENST00000313250.5:c.307-1G>A p.X103_splice ENST00000313250 NM_021004.2 0 +DHRS4L2 UCSF GRCh37 14 24464240 24464240 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 424 90 413 0 ENST00000335125.6:c.307-1G>A p.X103_splice ENST00000335125 NM_198083.3 0 +DHX16 UCSF GRCh37 6 30622538 30622538 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 83 135 0 ENST00000376442.3:c.2942C>T p.Pro981Leu p.P981L ENST00000376442 NM_001164239.1 981 cCa/cTa 0 +DHX34 UCSF GRCh37 19 47865856 47865856 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 27 57 0 ENST00000328771.4:c.1499G>A p.Cys500Tyr p.C500Y ENST00000328771 NM_014681.5 500 tGc/tAc 0 +DHX36 UCSF GRCh37 3 154032946 154032946 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 86 158 0 ENST00000496811.1:c.492C>T p.Asp164= p.D164= ENST00000496811 NM_020865.2 164 gaC/gaT 0 +DHX38 UCSF GRCh37 16 72134369 72134369 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 43 80 0 ENST00000268482.3:c.1151C>T p.Thr384Ile p.T384I ENST00000268482 NM_014003.3 384 aCc/aTc 0 +DHX9 UCSF GRCh37 1 182849668 182849668 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 69 138 0 ENST00000367549.3:c.2549C>T p.Pro850Leu p.P850L ENST00000367549 NM_001357.4 850 cCt/cTt 0 +DIABLO UCSF GRCh37 12 122693086 122693086 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 44 113 0 ENST00000443649.3:c.562C>T p.Gln188Ter p.Q188* ENST00000443649 NM_019887.5 188 Cag/Tag 0 +DIEXF UCSF GRCh37 1 210024658 210024658 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 78 144 0 ENST00000491415.2:c.2137G>A p.Ala713Thr p.A713T ENST00000491415 NM_014388.6 713 Gcc/Acc 0 +DIP2B UCSF GRCh37 12 51069194 51069194 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 67 142 0 ENST00000301180.5:c.879G>A p.Lys293= p.K293= ENST00000301180 NM_173602.2 293 aaG/aaA 0 +DISP1 UCSF GRCh37 1 223164090 223164090 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 148 71 231 0 ENST00000284476.6:c.663G>A p.Leu221= p.L221= ENST00000284476 NM_032890.3 221 ctG/ctA 0 +DIXDC1 UCSF GRCh37 11 111857613 111857613 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 76 182 0 ENST00000440460.2:c.1024C>T p.Leu342= p.L342= ENST00000440460 NM_001037954.3 342 Ctg/Ttg 0 +DLG5 UCSF GRCh37 10 79579141 79579141 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 26 66 0 ENST00000372391.2:c.3609G>A p.Arg1203= p.R1203= ENST00000372391 NM_004747.3 1203 agG/agA 0 +DLGAP2 UCSF GRCh37 8 1497055 1497055 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 4 19 0 ENST00000421627.2:c.196G>A p.Val66Met p.V66M ENST00000421627 NM_004745.4 66 Gtg/Atg 0 +DLGAP3 UCSF GRCh37 1 35369974 35369974 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 67 123 0 ENST00000373347.1:c.1011C>T p.Val337= p.V337= ENST00000373347 337 gtC/gtT 0 +DLK2 UCSF GRCh37 6 43420863 43420863 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 37 62 0 ENST00000357338.3:c.151G>A p.Gly51Ser p.G51S ENST00000357338 NM_206539.1 51 Ggc/Agc 0 +DLL1 UCSF GRCh37 6 170597827 170597827 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 68 190 0 ENST00000366756.3:c.402C>T p.Asp134= p.D134= ENST00000366756 NM_005618.3 134 gaC/gaT 0 +DMAP1 UCSF GRCh37 1 44684045 44684045 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 104 193 0 ENST00000372289.2:c.456G>A p.Trp152Ter p.W152* ENST00000372289 NM_019100.4 152 tgG/tgA 0 +DMXL1 UCSF GRCh37 5 118470064 118470064 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 182 101 326 1 ENST00000311085.8:c.2356C>T p.Leu786Phe p.L786F ENST00000311085 NM_005509.4 786 Ctt/Ttt 0 +DNAAF1 UCSF GRCh37 16 84188229 84188229 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 49 159 0 ENST00000378553.5:c.400C>T p.Leu134Phe p.L134F ENST00000378553 NM_178452.4 134 Ctc/Ttc 0 +DNAH14 UCSF GRCh37 1 225334902 225334902 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 102 197 0 ENST00000328556.5:c.2125G>A p.Ala709Thr p.A709T ENST00000328556 709 Gcc/Acc 0 +DNAH14 UCSF GRCh37 1 225577523 225577523 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 173 125 258 0 ENST00000428003.2:c.82C>T p.Phe28= p.F28= ENST00000428003 28 ttC/ttT 0 +DNAH17 UCSF GRCh37 17 76525584 76525584 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 98 191 0 ENST00000389840.5:c.3477G>A p.Glu1159= p.E1159= ENST00000389840 1159 gaG/gaA 0 +DNAH2 UCSF GRCh37 17 7736727 7736727 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 43 139 0 ENST00000572933.1:c.13160C>T p.Pro4387Leu p.P4387L ENST00000572933 4387 cCc/cTc 0 +DNAH2 UCSF GRCh37 17 7637966 7637966 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 70 159 0 ENST00000572933.1:c.918C>T p.Ile306= p.I306= ENST00000572933 306 atC/atT 0 +DNAH3 UCSF GRCh37 16 21080757 21080757 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 86 221 0 ENST00000261383.3:c.3360G>A p.Trp1120Ter p.W1120* ENST00000261383 NM_017539.1 1120 tgG/tgA 0 +DNAH7 UCSF GRCh37 2 196728926 196728926 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 71 140 0 ENST00000312428.6:c.7453C>T p.Arg2485Cys p.R2485C ENST00000312428 NM_018897.2 2485 Cgt/Tgt 0 +DNAH8 UCSF GRCh37 6 38690880 38690880 + upstream_gene_variant 5'Flank SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 188 157 297 0 ENST00000359357 0 +DNAH9 UCSF GRCh37 17 11835454 11835454 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 82 210 0 ENST00000262442.4:c.12229C>T p.Pro4077Ser p.P4077S ENST00000262442 NM_001372.3 4077 Ccc/Tcc 0 +DNAH9 UCSF GRCh37 17 11865278 11865278 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 125 96 226 0 ENST00000262442.4:c.12938C>T p.Ser4313Phe p.S4313F ENST00000262442 NM_001372.3 4313 tCc/tTc 0 +DNAH9 UCSF GRCh37 17 11523033 11523033 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 157 116 237 0 ENST00000262442.4:c.1285G>A p.Asp429Asn p.D429N ENST00000262442 NM_001372.3 429 Gat/Aat 0 +DNAH9 UCSF GRCh37 17 11865433 11865433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 124 184 0 ENST00000262442.4:c.13093C>T p.Arg4365Cys p.R4365C ENST00000262442 NM_001372.3 4365 Cgc/Tgc 0 +DNAI2 UCSF GRCh37 17 72295924 72295924 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 41 89 0 ENST00000446837.2:c.792C>T p.Asp264= p.D264= ENST00000446837 264 gaC/gaT 0 +DNAJC1 UCSF GRCh37 10 22171240 22171240 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 40 95 1 ENST00000376980.3:c.949G>A p.Glu317Lys p.E317K ENST00000376980 NM_022365.3 317 Gaa/Aaa 0 +DNAJC2 UCSF GRCh37 7 102957397 102957397 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 131 89 211 0 ENST00000379263.3:c.1307C>T p.Ala436Val p.A436V ENST00000379263 NM_014377.1 436 gCa/gTa 0 +DNASE1L1 UCSF GRCh37 X 153633810 153633810 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 39 24 0 ENST00000369809.1:c.100G>A p.Val34Met p.V34M ENST00000369809 NM_001009932.1 34 Gtg/Atg 0 +DNHD1 UCSF GRCh37 11 6588286 6588286 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 98 207 0 ENST00000254579.6:c.11547C>T p.Pro3849= p.P3849= ENST00000254579 NM_144666.2 3849 ccC/ccT 0 +DNM2 UCSF GRCh37 19 10916604 10916604 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 43 111 0 ENST00000389253.4:c.1506G>A p.Arg502= p.R502= ENST00000389253 NM_001005361.2 502 agG/agA 0 +DOCK1 UCSF GRCh37 10 129172097 129172097 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 57 169 0 ENST00000280333.6:c.3422G>A p.Gly1141Glu p.G1141E ENST00000280333 NM_001380.3 1141 gGa/gAa 0 +DOCK10 UCSF GRCh37 2 225714287 225714287 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 50 0 ENST00000258390.7:c.2172C>T p.Leu724= p.L724= ENST00000258390 NM_014689.2 724 ctC/ctT 0 +DOCK3 UCSF GRCh37 3 51308422 51308422 + synonymous_variant Silent SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 164 137 259 0 ENST00000266037.9:c.2532C>T p.Arg844= p.R844= ENST00000266037 NM_004947.4 844 cgC/cgT 0 +DOCK3 UCSF GRCh37 3 51264836 51264836 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 168 133 285 0 ENST00000266037.9:c.1500C>T p.Phe500= p.F500= ENST00000266037 NM_004947.4 500 ttC/ttT 0 +DOCK7 UCSF GRCh37 1 63027353 63027353 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 107 65 161 0 ENST00000340370.5:c.2134T>C p.Trp712Arg p.W712R ENST00000340370 NM_033407.3 712 Tgg/Cgg 0 +DOK2 UCSF GRCh37 8 21766883 21766883 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 61 134 0 ENST00000276420.4:c.1178C>T p.Ala393Val p.A393V ENST00000276420 NM_003974.2 393 gCt/gTt 0 +DOM3Z UCSF GRCh37 6 31939281 31939281 + missense_variant Missense_Mutation SNP G G A snp132_rs115027323 P18_Rec Untested WXS Illumina HiSeq 65 59 98 0 ENST00000375349.3:c.172C>T p.Arg58Cys p.R58C ENST00000375349 58 Cgc/Tgc 0 +DPEP3 UCSF GRCh37 16 68014163 68014163 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 18 30 0 ENST00000268793.4:c.196G>A p.Gly66Ser p.G66S ENST00000268793 NM_022357.3 66 Ggc/Agc 0 +DPF1 UCSF GRCh37 19 38713026 38713026 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 63 130 0 ENST00000355526.4:c.350C>T p.Pro117Leu p.P117L ENST00000355526 NM_001135155.1 117 cCc/cTc 0 +DPH2 UCSF GRCh37 1 44436675 44436675 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 11 15 0 ENST00000255108.3:c.298G>A p.Ala100Thr p.A100T ENST00000255108 NM_001384.4 100 Gct/Act 0 +DPH2 UCSF GRCh37 1 44437200 44437200 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 77 149 0 ENST00000255108.3:c.626G>A p.Arg209Lys p.R209K ENST00000255108 NM_001384.4 209 aGg/aAg 0 +DPY19L3 UCSF GRCh37 19 32971452 32971452 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 42 75 0 ENST00000342179.5:c.1978G>A p.Ala660Thr p.A660T ENST00000342179 NM_207325.2 660 Gcc/Acc 0 +DPY19L4 UCSF GRCh37 8 95793303 95793310 + splice_acceptor_variant,intron_variant Splice_Site INS GCATTTTA GCATTTTA TTCCTTTTT NOVEL P18_Rec Untested WXS Illumina HiSeq 10 0 ENST00000414645.2:c.1633-9_1633-2delinsTTCCTTTTT p.X545_splice ENST00000414645 NM_181787.2 0 +DPYD UCSF GRCh37 1 97564070 97564070 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 93 247 0 ENST00000370192.3:c.2741C>T p.Pro914Leu p.P914L ENST00000370192 NM_000110.3 914 cCc/cTc 0 +DPYSL2 UCSF GRCh37 8 26485411 26485411 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 19 50 0 ENST00000311151.5:c.645G>A p.Leu215= p.L215= ENST00000311151 NM_001386.5 215 ctG/ctA 0 +DSCAML1 UCSF GRCh37 11 117387190 117387190 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 21 54 0 ENST00000321322.6:c.1955C>T p.Ala652Val p.A652V ENST00000321322 NM_020693.2 652 gCc/gTc 0 +DSCR4 UCSF GRCh37 21 39492435 39492435 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 46 116 0 ENST00000328264.3:c.196C>T p.Pro66Ser p.P66S ENST00000328264 NM_005867.2 66 Cct/Tct 0 +DSP UCSF GRCh37 6 7582925 7582925 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 122 86 172 0 ENST00000379802.3:c.5430G>A p.Gln1810= p.Q1810= ENST00000379802 NM_004415.2 1810 caG/caA 0 +DSPP UCSF GRCh37 4 88534257 88534257 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 56 166 1 ENST00000399271.1:c.919C>A p.Pro307Thr p.P307T ENST00000399271 NM_014208.3 307 Cct/Act 0 +DST UCSF GRCh37 6 56330989 56330989 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 86 210 0 ENST00000244364.6:c.14705G>A p.Gly4902Glu p.G4902E ENST00000244364 NM_015548.4 4902 gGa/gAa 0 +DST UCSF GRCh37 6 56422302 56422302 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 71 170 0 ENST00000244364.6:c.6586G>A p.Glu2196Lys p.E2196K ENST00000244364 NM_015548.4 2196 Gaa/Aaa 0 +DST UCSF GRCh37 6 56433267 56433267 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 191 128 295 0 ENST00000244364.6:c.6136G>A p.Gly2046Ser p.G2046S ENST00000244364 NM_015548.4 2046 Ggt/Agt 0 +DUOX2 UCSF GRCh37 15 45393011 45393011 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 58 119 0 ENST00000603300.1:c.2947C>T p.Pro983Ser p.P983S ENST00000603300 NM_014080.4 983 Cct/Tct 0 +DUOX2 UCSF GRCh37 15 45401098 45401098 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 67 170 0 ENST00000603300.1:c.1287C>T p.Ser429= p.S429= ENST00000603300 NM_014080.4 429 agC/agT 0 +DUS1L UCSF GRCh37 17 80022025 80022025 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 20 46 0 ENST00000354321.7:c.323G>A p.Cys108Tyr p.C108Y ENST00000354321 108 tGc/tAc 0 +DUSP11 UCSF GRCh37 2 74005494 74005494 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 54 127 0 ENST00000272444.3:c.252C>T p.Asp84= p.D84= ENST00000272444 NM_003584.2 84 gaC/gaT 0 +DUSP22 UCSF GRCh37 6 348153 348153 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 225 73 284 0 ENST00000344450.5:c.314C>T p.Thr105Ile p.T105I ENST00000344450 NM_020185.3 105 aCc/aTc 0 +DUSP22 UCSF GRCh37 6 345859 345859 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 27 113 0 ENST00000344450.5:c.194G>A p.Arg65Lys p.R65K ENST00000344450 NM_020185.3 65 aGa/aAa 0 +DVL2 UCSF GRCh37 17 7133431 7133431 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 63 153 0 ENST00000005340.5:c.454G>A p.Glu152Lys p.E152K ENST00000005340 NM_004422.2 152 Gaa/Aaa 0 +DYNC1H1 UCSF GRCh37 14 102446879 102446879 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 41 88 0 ENST00000360184.4:c.953C>T p.Thr318Ile p.T318I ENST00000360184 NM_001376.4 318 aCt/aTt 0 +DYTN UCSF GRCh37 2 207572123 207572123 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 75 178 0 ENST00000452335.2:c.199C>T p.Gln67Ter p.Q67* ENST00000452335 NM_001093730.1 67 Caa/Taa 0 +DZIP3 UCSF GRCh37 3 108403174 108403174 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 195 146 283 0 ENST00000361582.3:c.2995C>T p.Pro999Ser p.P999S ENST00000361582 NM_014648.3 999 Cct/Tct 0 +E2F3 UCSF GRCh37 6 20483110 20483110 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 65 163 0 ENST00000346618.3:c.843C>T p.Thr281= p.T281= ENST00000346618 NM_001949.4 281 acC/acT 0 +E2F8 UCSF GRCh37 11 19259421 19259421 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 176 113 256 0 ENST00000527884.1:c.274G>A p.Glu92Lys p.E92K ENST00000527884 NM_001256372.1 92 Gag/Aag 0 +E4F1 UCSF GRCh37 16 2282801 2282801 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 45 99 0 ENST00000301727.4:c.775G>A p.Glu259Lys p.E259K ENST00000301727 NM_004424.3 259 Gag/Aag 0 +EBF3 UCSF GRCh37 10 131755587 131755587 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 77 156 0 ENST00000368648.3:c.489G>A p.Arg163= p.R163= ENST00000368648 NM_001005463.2 163 cgG/cgA 0 +ECD UCSF GRCh37 10 74923685 74923685 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 83 175 0 ENST00000430082.2:c.11C>T p.Thr4Ile p.T4I ENST00000430082 NM_001135752.1 4 aCc/aTc 0 +ECE2 UCSF GRCh37 3 184009200 184009200 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 29 81 0 ENST00000402825.3:c.2448C>T p.His816= p.H816= ENST00000402825 NM_014693.3 816 caC/caT 0 +ECEL1 UCSF GRCh37 2 233346327 233346327 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 14 38 0 ENST00000304546.1:c.1878C>T p.Asp626= p.D626= ENST00000304546 NM_004826.2 626 gaC/gaT 0 +ECT2L UCSF GRCh37 6 139186154 139186154 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 43 133 0 ENST00000423192.1:c.1313C>T p.Ser438Phe p.S438F ENST00000423192 438 tCc/tTc 0 +EDC4 UCSF GRCh37 16 67914460 67914460 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 85 181 0 ENST00000358933.5:c.2098G>A p.Val700Met p.V700M ENST00000358933 NM_014329.4 700 Gtg/Atg 0 +EDDM3B UCSF GRCh37 14 21238360 21238360 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 65 129 0 ENST00000326783.3:c.51C>T p.Ile17= p.I17= ENST00000326783 NM_022360.4 17 atC/atT 0 +EEF1G UCSF GRCh37 11 62339367 62339367 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 43 82 0 ENST00000329251.4:c.178G>A p.Ala60Thr p.A60T ENST00000329251 NM_001404.4 60 Gca/Aca 0 +EEFSEC UCSF GRCh37 3 128060344 128060344 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 84 68 139 0 ENST00000254730.6:c.1055G>A p.Ser352Asn p.S352N ENST00000254730 NM_021937.3 352 aGt/aAt 0 +EFCAB4B UCSF GRCh37 12 3757770 3757770 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 44 29 76 0 ENST00000440314.2:c.1056C>T p.Tyr352= p.Y352= ENST00000440314 NM_001144958.1 352 taC/taT 0 +EFNA2 UCSF GRCh37 19 1295590 1295590 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 8 26 0 ENST00000215368.2:c.187G>A p.Val63Met p.V63M ENST00000215368 NM_001405.3 63 Gtg/Atg 0 +EFNA3 UCSF GRCh37 1 155058671 155058671 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 13 37 0 ENST00000368408.3:c.576C>T p.Ile192= p.I192= ENST00000368408 NM_004952.4 192 atC/atT 0 +EFS UCSF GRCh37 14 23829833 23829833 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 28 70 0 ENST00000216733.3:c.228C>T p.Leu76= p.L76= ENST00000216733 NM_005864.3 76 ctC/ctT 0 +EGFR UCSF GRCh37 7 55242501 55242501 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 56 144 0 ENST00000275493.2:c.2271G>A p.Lys757= p.K757= ENST00000275493 NM_005228.3 757 aaG/aaA 0 +EGR2 UCSF GRCh37 10 64574204 64574204 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 49 111 0 ENST00000242480.3:c.194C>T p.Thr65Ile p.T65I ENST00000242480 NM_001136177.1 65 aCt/aTt 0 +EHD2 UCSF GRCh37 19 48220001 48220001 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 19 51 0 ENST00000263277.3:c.132C>T p.Ala44= p.A44= ENST00000263277 NM_014601.3 44 gcC/gcT 0 +EHMT2 UCSF GRCh37 6 31854826 31854826 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 37 74 0 ENST00000375537.4:c.2064C>T p.Pro688= p.P688= ENST00000375537 NM_006709.3 688 ccC/ccT 0 +EHMT2 UCSF GRCh37 6 31864507 31864507 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 55 146 0 ENST00000375537.4:c.204C>T p.Ala68= p.A68= ENST00000375537 NM_006709.3 68 gcC/gcT 0 +EIF2AK1 UCSF GRCh37 7 6064421 6064421 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 84 178 0 ENST00000199389.6:c.1776C>T p.Thr592= p.T592= ENST00000199389 NM_001134335.1 592 acC/acT 0 +EIF2C1 UCSF GRCh37 1 36385140 36385140 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 15 46 0 ENST00000373204.4:c.2506G>A p.Asp836Asn p.D836N ENST00000373204 NM_012199.2 836 Gac/Aac 0 +EIF2C2 UCSF GRCh37 8 141568663 141568663 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 49 114 0 ENST00000220592.5:c.799G>A p.Val267Met p.V267M ENST00000220592 NM_012154.3 267 Gtg/Atg 0 +EIF3A UCSF GRCh37 10 120833414 120833414 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 63 127 0 ENST00000369144.3:c.85G>A p.Asp29Asn p.D29N ENST00000369144 NM_003750.2 29 Gat/Aat 0 +EIF5B UCSF GRCh37 2 99984995 99984995 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 43 115 0 ENST00000289371.6:c.1328G>A p.Arg443Lys p.R443K ENST00000289371 NM_015904.3 443 aGg/aAg 0 +ELF1 UCSF GRCh37 13 41515250 41515250 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 134 270 0 ENST00000239882.3:c.1063C>T p.Pro355Ser p.P355S ENST00000239882 NM_172373.3 355 Ccc/Tcc 0 +ELF5 UCSF GRCh37 11 34502512 34502512 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 48 127 0 ENST00000312319.2:c.508C>T p.Leu170Phe p.L170F ENST00000312319 NM_001243081.1 170 Ctc/Ttc 0 +ELP4 UCSF GRCh37 11 31531461 31531461 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 30 71 0 ENST00000350638.5:c.130C>T p.Pro44Ser p.P44S ENST00000350638 NM_019040.3 44 Cct/Tct 0 +ELP4 UCSF GRCh37 11 31561313 31561313 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 97 192 0 ENST00000350638.5:c.364C>T p.Pro122Ser p.P122S ENST00000350638 NM_019040.3 122 Cct/Tct 0 +EMID1 UCSF GRCh37 22 29654839 29654839 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 26 69 0 ENST00000334018.6:c.1238G>A p.Gly413Asp p.G413D ENST00000334018 NM_001267895.1 413 gGc/gAc 0 +EML4 UCSF GRCh37 2 42513493 42513493 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 125 195 0 ENST00000318522.5:c.1096G>A p.Val366Ile p.V366I ENST00000318522 NM_019063.3 366 Gta/Ata 0 +ENC1 UCSF GRCh37 5 73932029 73932029 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 72 159 0 ENST00000302351.4:c.282C>T p.His94= p.H94= ENST00000302351 NM_003633.3 94 caC/caT 0 +ENOSF1 UCSF GRCh37 18 677400 677400 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 60 156 0 ENST00000340116.7:c.1114G>A p.Val372Met p.V372M ENST00000340116 NM_202758.3 372 Gtg/Atg 0 +ENPP2 UCSF GRCh37 8 120575108 120575108 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 57 170 0 ENST00000259486.6:c.2566G>A p.Glu856Lys p.E856K ENST00000259486 NM_006209.4 856 Gag/Aag 0 +ENPP3 UCSF GRCh37 6 131962671 131962671 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 51 86 0 ENST00000414305.1:c.154+1G>A p.X52_splice ENST00000414305 0 +EP300 UCSF GRCh37 22 41554450 41554450 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 45 93 0 ENST00000263253.7:c.3536G>A p.Gly1179Asp p.G1179D ENST00000263253 NM_001429.3 1179 gGc/gAc 0 +EP400 UCSF GRCh37 12 132445312 132445312 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 35 73 0 ENST00000389561.2:c.148G>A p.Ala50Thr p.A50T ENST00000389561 NM_015409.4 50 Gca/Aca 0 +EPB41L1 UCSF GRCh37 20 34802304 34802304 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 29 51 0 ENST00000338074.2:c.2210G>A p.Gly737Glu p.G737E ENST00000338074 NM_012156.2 737 gGg/gAg 0 +EPB42 UCSF GRCh37 15 43489632 43489632 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 49 120 0 ENST00000300215.3:c.2034G>A p.Met678Ile p.M678I ENST00000300215 678 atG/atA 0 +EPG5 UCSF GRCh37 18 43460180 43460180 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 48 88 0 ENST00000282041.5:c.5527G>A p.Glu1843Lys p.E1843K ENST00000282041 NM_020964.2 1843 Gag/Aag 0 +EPHA3 UCSF GRCh37 3 89259579 89259579 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 191 130 282 0 ENST00000336596.2:c.723G>A p.Arg241= p.R241= ENST00000336596 NM_005233.5 241 agG/agA 0 +EPHB2 UCSF GRCh37 1 23233224 23233224 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 34 36 83 0 ENST00000374632.3:c.1913G>A p.Ser638Asn p.S638N ENST00000374632 638 aGt/aAt 0 +EPHB2 UCSF GRCh37 1 23236953 23236953 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 61 128 0 ENST00000374632.3:c.2584G>A p.Asp862Asn p.D862N ENST00000374632 862 Gac/Aac 0 +EPHB4 UCSF GRCh37 7 100405188 100405188 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 43 138 0 ENST00000358173.3:c.2133G>A p.Gln711= p.Q711= ENST00000358173 NM_004444.4 711 caG/caA 0 +EPM2AIP1 UCSF GRCh37 3 37033760 37033760 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 107 184 0 ENST00000322716.5:c.809C>T p.Pro270Leu p.P270L ENST00000322716 NM_014805.3 270 cCc/cTc 0 +EPPK1 UCSF GRCh37 8 144941870 144941870 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 91 194 1 ENST00000525985.1:c.5552G>A p.Arg1851Lys p.R1851K ENST00000525985 NM_031308.2 1851 aGa/aAa 0 +EPPK1 UCSF GRCh37 8 144945283 144945283 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 65 146 0 ENST00000525985.1:c.2139G>A p.Arg713= p.R713= ENST00000525985 NM_031308.2 713 cgG/cgA 0 +EPX UCSF GRCh37 17 56274611 56274611 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 43 97 0 ENST00000225371.5:c.1113C>T p.Phe371= p.F371= ENST00000225371 NM_000502.4 371 ttC/ttT 0 +ERAP1 UCSF GRCh37 5 96139106 96139106 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 69 147 0 ENST00000296754.3:c.524G>A p.Arg175Lys p.R175K ENST00000296754 NM_016442.3 175 aGg/aAg 0 +ERBB2IP UCSF GRCh37 5 65350661 65350661 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 51 156 0 ENST00000506030.1:c.3515G>A p.Arg1172Lys p.R1172K ENST00000506030 1172 aGa/aAa 0 +ERBB4 UCSF GRCh37 2 212483992 212483992 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 39 98 0 ENST00000342788.4:c.2211G>A p.Trp737Ter p.W737* ENST00000342788 NM_005235.2 737 tgG/tgA 0 +ERP27 UCSF GRCh37 12 15070178 15070178 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 85 198 0 ENST00000266397.2:c.510G>A p.Lys170= p.K170= ENST00000266397 NM_152321.2 170 aaG/aaA 0 +ESRRB UCSF GRCh37 14 76966402 76966402 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 63 139 0 ENST00000380887.2:c.1493G>A p.Gly498Glu p.G498E ENST00000380887 498 gGa/gAa 0 +ESRRG UCSF GRCh37 1 216692502 216692502 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 45 152 0 ENST00000366937.1:c.1160C>T p.Ala387Val p.A387V ENST00000366937 NM_001243518.1 387 gCt/gTt 0 +ETFB UCSF GRCh37 19 51869553 51869553 + intron_variant,NMD_transcript_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 16 26 0 ENST00000600067.1:c.115+1587G>A *39* ENST00000600067 0 +ETFDH UCSF GRCh37 4 159627470 159627470 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 73 156 0 ENST00000511912.1:c.1415G>A p.Gly472Glu p.G472E ENST00000511912 NM_004453.2 472 gGa/gAa 0 +ETS1 UCSF GRCh37 11 128359262 128359262 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 174 153 313 0 ENST00000392668.4:c.458G>A p.Gly153Asp p.G153D ENST00000392668 NM_001143820.1 153 gGt/gAt 0 +ETV3 UCSF GRCh37 1 157095543 157095543 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 31 46 0 ENST00000368192.4:c.629C>T p.Ser210Phe p.S210F ENST00000368192 NM_001145312.1 210 tCc/tTc 0 +EXOC6 UCSF GRCh37 10 94700484 94700484 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 27 88 0 ENST00000260762.6:c.1213G>A p.Gly405Ser p.G405S ENST00000260762 NM_019053.4 405 Ggt/Agt 0 +EXOSC2 UCSF GRCh37 9 133573605 133573605 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 54 89 0 ENST00000372358.5:c.327G>A p.Leu109= p.L109= ENST00000372358 109 ctG/ctA 0 +EXPH5 UCSF GRCh37 11 108382821 108382821 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 75 222 0 ENST00000265843.4:c.3413G>A p.Gly1138Glu p.G1138E ENST00000265843 NM_015065.2 1138 gGa/gAa 0 +EYA3 UCSF GRCh37 1 28362189 28362189 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 88 209 0 ENST00000373871.3:c.227C>T p.Pro76Leu p.P76L ENST00000373871 76 cCt/cTt 0 +EZR UCSF GRCh37 6 159205752 159205752 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 32 91 0 ENST00000367075.3:c.475G>A p.Asp159Asn p.D159N ENST00000367075 NM_001111077.1 159 Gac/Aac 0 +F2RL3 UCSF GRCh37 19 17000773 17000773 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 6 19 0 ENST00000248076.3:c.499C>T p.Leu167= p.L167= ENST00000248076 NM_003950.2 167 Ctg/Ttg 0 +FAF1 UCSF GRCh37 1 51253837 51253837 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 56 168 0 ENST00000396153.2:c.202C>T p.Pro68Ser p.P68S ENST00000396153 NM_007051.2 68 Cca/Tca 0 +FAF2 UCSF GRCh37 5 175913454 175913454 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 70 145 0 ENST00000261942.6:c.231G>A p.Arg77= p.R77= ENST00000261942 NM_014613.2 77 agG/agA 0 +FAM105A UCSF GRCh37 5 14609106 14609106 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0011 P18_Rec Untested WXS Illumina HiSeq 208 135 280 0 ENST00000274217.3:c.877G>A p.Asp293Asn p.D293N ENST00000274217 NM_019018.2 293 Gac/Aac 0 +FAM107B UCSF GRCh37 10 14816616 14816616 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 71 149 0 ENST00000181796.2:c.47C>T p.Ser16Phe p.S16F ENST00000181796 NM_031453.2 16 tCt/tTt 0 +FAM109B UCSF GRCh37 22 42474031 42474031 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 9 20 0 ENST00000321753.3:c.734G>A p.Arg245Lys p.R245K ENST00000321753 NM_001002034.2 245 aGg/aAg 0 +FAM110B UCSF GRCh37 8 59059803 59059803 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 60 112 0 ENST00000361488.3:c.1014G>A p.Val338= p.V338= ENST00000361488 NM_147189.2 338 gtG/gtA 0 +FAM116A UCSF GRCh37 3 57614579 57614579 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 84 204 0 ENST00000311128.5:c.1654G>A p.Val552Ile p.V552I ENST00000311128 NM_152678.2 552 Gta/Ata 0 +FAM123C UCSF GRCh37 2 131519926 131519926 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 12 28 0 ENST00000423981.1:c.281C>T p.Thr94Ile p.T94I ENST00000423981 NM_001105194.1 94 aCt/aTt 0 +FAM129C UCSF GRCh37 19 17653039 17653039 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 82 145 1 ENST00000335393.4:c.1358C>T p.Ala453Val p.A453V ENST00000335393 NM_173544.4 453 gCa/gTa 0 +FAM131C UCSF GRCh37 1 16386429 16386429 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 6 36 0 ENST00000375662.4:c.386C>T p.Ser129Phe p.S129F ENST00000375662 NM_182623.2 129 tCc/tTc 0 +FAM13B UCSF GRCh37 5 137278595 137278595 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 111 209 0 ENST00000033079.3:c.2491C>T p.Leu831Phe p.L831F ENST00000033079 NM_016603.2 831 Ctc/Ttc 0 +FAM149A UCSF GRCh37 4 187078868 187078868 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 72 113 0 ENST00000227065.4:c.724C>T p.Pro242Ser p.P242S ENST00000227065 NM_015398.2 242 Ccc/Tcc 0 +FAM149B1 UCSF GRCh37 10 74995047 74995047 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 142 105 226 0 ENST00000242505.6:c.1573C>T p.Pro525Ser p.P525S ENST00000242505 NM_173348.1 525 Ccc/Tcc 0 +FAM154B UCSF GRCh37 15 82574934 82574934 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 69 170 0 ENST00000339465.5:c.728G>A p.Gly243Asp p.G243D ENST00000339465 NM_001008226.1 243 gGt/gAt 0 +FAM160A2 UCSF GRCh37 11 6245656 6245656 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 50 137 0 ENST00000265978.4:c.91G>A p.Ala31Thr p.A31T ENST00000265978 NM_032127.3 31 Gct/Act 0 +FAM161B UCSF GRCh37 14 74411536 74411536 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 21 43 0 ENST00000286544.3:c.616C>A p.Pro206Thr p.P206T ENST00000286544 NM_152445.2 206 Ccc/Acc 0 +FAM163A UCSF GRCh37 1 179783116 179783116 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 32 83 0 ENST00000341785.4:c.296C>T p.Ser99Phe p.S99F ENST00000341785 NM_173509.2 99 tCc/tTc 0 +FAM171B UCSF GRCh37 2 187605111 187605111 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 68 159 1 ENST00000304698.5:c.395G>A p.Gly132Glu p.G132E ENST00000304698 NM_177454.3 132 gGa/gAa 0 +FAM171B UCSF GRCh37 2 187627152 187627152 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 76 160 0 ENST00000304698.5:c.2083G>A p.Gly695Ser p.G695S ENST00000304698 NM_177454.3 695 Ggc/Agc 0 +FAM178B UCSF GRCh37 2 97637810 97637810 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 16 0 ENST00000490605.2:c.392C>T p.Ala131Val p.A131V ENST00000490605 131 gCc/gTc 0 +FAM180B UCSF GRCh37 11 47609803 47609803 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 34 83 0 ENST00000356737.2:c.492C>T p.Leu164= p.L164= ENST00000356737 164 ctC/ctT 0 +FAM184B UCSF GRCh37 4 17654527 17654527 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 11 20 0 ENST00000265018.3:c.2117C>T p.Ala706Val p.A706V ENST00000265018 NM_015688.1 706 gCc/gTc 0 +FAM188A UCSF GRCh37 10 15902243 15902243 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 19 28 0 ENST00000277632.3:c.56C>T p.Pro19Leu p.P19L ENST00000277632 NM_024948.2 19 cCc/cTc 0 +FAM194B UCSF GRCh37 13 46171026 46171026 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 95 220 0 ENST00000298738.2:c.115G>A p.Asp39Asn p.D39N ENST00000298738 NM_182542.2 39 Gat/Aat 0 +FAM203A UCSF GRCh37 8 145193675 145193675 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 29 88 0 ENST00000347708.4:c.752C>T p.Pro251Leu p.P251L ENST00000347708 NM_016458.2 251 cCc/cTc 0 +FAM208B UCSF GRCh37 10 5788719 5788719 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 358 148 299 0 ENST00000328090.5:c.3335C>T p.Ser1112Phe p.S1112F ENST00000328090 NM_017782.4 1112 tCt/tTt 0 +FAM20A UCSF GRCh37 17 66537057 66537057 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 18 20 34 0 ENST00000592554.1:c.1152C>T p.Ile384= p.I384= ENST00000592554 NM_001243746.1 384 atC/atT 0 +FAM32A UCSF GRCh37 19 16296498 16296498 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 11 24 0 ENST00000263384.7:c.138G>A p.Lys46= p.K46= ENST00000263384 NM_014077.2 46 aaG/aaA 0 +FAM40A UCSF GRCh37 1 110590402 110590402 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 8 13 0 ENST00000369795.3:c.1572C>T p.Leu524= p.L524= ENST00000369795 NM_033088.3 524 ctC/ctT 0 +FAM47E UCSF GRCh37 4 77199326 77199326 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 59 125 0 ENST00000424749.2:c.975G>A p.Glu325= p.E325= ENST00000424749 NM_001136570.2 325 gaG/gaA 0 +FAM65A UCSF GRCh37 16 67572917 67572917 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 35 103 0 ENST00000422602.2:c.342G>A p.Gln114= p.Q114= ENST00000422602 NM_001193523.1 114 caG/caA 0 +FAM71B UCSF GRCh37 5 156590120 156590120 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 46 101 0 ENST00000302938.4:c.1156G>A p.Ala386Thr p.A386T ENST00000302938 NM_130899.2 386 Gca/Aca 0 +FAM71F1 UCSF GRCh37 7 128355653 128355653 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 73 128 0 ENST00000315184.5:c.158G>A p.Gly53Asp p.G53D ENST00000315184 NM_032599.2 53 gGt/gAt 0 +FAM73B UCSF GRCh37 9 131825526 131825526 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 13 51 0 ENST00000358369.4:c.1014G>A p.Thr338= p.T338= ENST00000358369 NM_032809.2 338 acG/acA 0 +FAM83G UCSF GRCh37 17 18891670 18891670 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 64 158 0 ENST00000388995.6:c.580G>A p.Asp194Asn p.D194N ENST00000388995 194 Gac/Aac 0 +FAM84A UCSF GRCh37 2 14774968 14774968 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 28 46 0 ENST00000295092.2:c.865G>A p.Asp289Asn p.D289N ENST00000295092 NM_145175.2 289 Gac/Aac 0 +FANCD2 UCSF GRCh37 3 10128823 10128823 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 201 147 313 0 ENST00000287647.3:c.3341G>A p.Ser1114Asn p.S1114N ENST00000287647 NM_033084.3 1114 aGc/aAc 0 +FANCM UCSF GRCh37 14 45636326 45636326 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 88 200 0 ENST00000267430.5:c.1962G>A p.Arg654= p.R654= ENST00000267430 NM_020937.2 654 cgG/cgA 0 +FARP1 UCSF GRCh37 13 99047730 99047730 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 37 101 0 ENST00000319562.6:c.1414G>A p.Gly472Ser p.G472S ENST00000319562 NM_005766.2 472 Ggc/Agc 0 +FARSB UCSF GRCh37 2 223464748 223464748 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 118 210 0 ENST00000281828.6:c.1517C>T p.Pro506Leu p.P506L ENST00000281828 NM_005687.3 506 cCt/cTt 0 +FASN UCSF GRCh37 17 80045130 80045130 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 5 26 0 ENST00000306749.2:c.3224-1G>A p.X1075_splice ENST00000306749 NM_004104.4 0 +FAT1 UCSF GRCh37 4 187558026 187558026 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 219 182 348 0 ENST00000441802.2:c.3685G>A p.Ala1229Thr p.A1229T ENST00000441802 NM_005245.3 1229 Gca/Aca 0 +FAT1 UCSF GRCh37 4 187516856 187516856 + synonymous_variant Silent SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 118 277 0 ENST00000441802.2:c.13125G>T p.Ser4375= p.S4375= ENST00000441802 NM_005245.3 4375 tcG/tcT 0 +FAT3 UCSF GRCh37 11 92539561 92539561 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 89 197 0 ENST00000298047.6:c.9127C>T p.Pro3043Ser p.P3043S ENST00000298047 3043 Cca/Tca 0 +FAT3 UCSF GRCh37 11 92592401 92592401 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 167 97 211 0 ENST00000298047.6:c.11571G>A p.Glu3857= p.E3857= ENST00000298047 3857 gaG/gaA 0 +FAT4 UCSF GRCh37 4 126241968 126241968 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 93 210 0 ENST00000394329.3:c.4402C>T p.His1468Tyr p.H1468Y ENST00000394329 NM_024582.4 1468 Cac/Tac 0 +FAT4 UCSF GRCh37 4 126239253 126239253 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 61 162 0 ENST00000394329.3:c.1687G>A p.Val563Met p.V563M ENST00000394329 NM_024582.4 563 Gtg/Atg 0 +FAT4 UCSF GRCh37 4 126411568 126411568 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 93 185 0 ENST00000394329.3:c.13591G>A p.Gly4531Arg p.G4531R ENST00000394329 NM_024582.4 4531 Ggg/Agg 0 +FBN2 UCSF GRCh37 5 127674694 127674694 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 79 176 0 ENST00000508053.1:c.3403C>T p.Pro1135Ser p.P1135S ENST00000508053 1135 Ccg/Tcg 0 +FBN3 UCSF GRCh37 19 8131101 8131101 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 27 46 0 ENST00000600128.1:c.8132G>A p.Gly2711Asp p.G2711D ENST00000600128 2711 gGc/gAc 0 +FBN3 UCSF GRCh37 19 8171033 8171033 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 47 81 0 ENST00000600128.1:c.4772C>T p.Pro1591Leu p.P1591L ENST00000600128 1591 cCa/cTa 0 +FBXL2 UCSF GRCh37 3 33418797 33418797 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 65 166 0 ENST00000484457.1:c.821C>T p.Thr274Ile p.T274I ENST00000484457 NM_012157.3 274 aCt/aTt 0 +FBXL5 UCSF GRCh37 4 15607372 15607372 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 28 78 0 ENST00000341285.3:c.2050C>T p.Arg684Ter p.R684* ENST00000341285 NM_001193534.1 684 Cga/Tga 0 +FBXO15 UCSF GRCh37 18 71797856 71797856 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 48 123 0 ENST00000419743.2:c.370C>T p.Pro124Ser p.P124S ENST00000419743 NM_001142958.1 124 Cct/Tct 0 +FBXO25 UCSF GRCh37 8 413085 413085 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 320 133 267 0 ENST00000276326.5:c.922C>T p.Pro308Ser p.P308S ENST00000276326 NM_183421.1 308 Cca/Tca 0 +FBXO34 UCSF GRCh37 14 55818764 55818764 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 152 97 239 0 ENST00000313833.4:c.1656G>A p.Lys552= p.K552= ENST00000313833 NM_017943.3 552 aaG/aaA 0 +FBXO36 UCSF GRCh37 2 230787285 230787285 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 36 77 0 ENST00000283946.3:c.56C>T p.Pro19Leu p.P19L ENST00000283946 NM_174899.4 19 cCt/cTt 0 +FBXO40 UCSF GRCh37 3 121341334 121341334 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 113 66 191 0 ENST00000338040.4:c.1058C>T p.Pro353Leu p.P353L ENST00000338040 NM_016298.3 353 cCt/cTt 0 +FCGBP UCSF GRCh37 19 40421162 40421162 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 37 50 0 ENST00000221347.6:c.2759C>T p.Thr920Met p.T920M ENST00000221347 NM_003890.2 920 aCg/aTg 0 +FCGR2B UCSF GRCh37 1 161642974 161642974 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 125 32 232 1 ENST00000358671.5:c.601G>A p.Gly201Ser p.G201S ENST00000358671 NM_001002275.2 201 Ggc/Agc 0 +FCRL1 UCSF GRCh37 1 157772450 157772450 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 29 72 0 ENST00000368176.3:c.324C>T p.Val108= p.V108= ENST00000368176 NM_001159398.1 108 gtC/gtT 0 +FCRL3 UCSF GRCh37 1 157659708 157659708 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 51 111 0 ENST00000368184.3:c.1691-1G>A p.X564_splice ENST00000368184 NM_052939.3 0 +FCRL5 UCSF GRCh37 1 157490246 157490246 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 8 21 0 ENST00000361835.3:c.2607C>T p.Leu869= p.L869= ENST00000361835 NM_001195388.1 869 ctC/ctT 0 +FCRLA UCSF GRCh37 1 161681016 161681016 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 33 52 1 ENST00000367959.2:c.320G>A p.Gly107Asp p.G107D ENST00000367959 NM_001184866.1 107 gGt/gAt 0 +FDXR UCSF GRCh37 17 72868192 72868192 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 23 42 0 ENST00000442102.2:c.146C>T p.Ala49Val p.A49V ENST00000442102 NM_001258012.1 49 gCt/gTt 0 +FEM1B UCSF GRCh37 15 68583057 68583057 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 124 255 0 ENST00000306917.4:c.1361C>T p.Ser454Phe p.S454F ENST00000306917 NM_015322.4 454 tCt/tTt 0 +FEM1C UCSF GRCh37 5 114860449 114860449 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 149 125 264 0 ENST00000274457.3:c.1410C>T p.Tyr470= p.Y470= ENST00000274457 NM_020177.2 470 taC/taT 0 +FER1L5 UCSF GRCh37 2 97361303 97361303 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 29 50 0 ENST00000397978.2:n.110G>A *37* ENST00000397978 0 +FER1L6 UCSF GRCh37 8 124978482 124978482 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 43 107 0 ENST00000522917.1:c.336G>A p.Lys112= p.K112= ENST00000522917 NM_001039112.2 112 aaG/aaA 0 +FERD3L UCSF GRCh37 7 19184684 19184684 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 46 82 0 ENST00000275461.3:c.302C>T p.Ala101Val p.A101V ENST00000275461 NM_152898.2 101 gCc/gTc 0 +FERMT3 UCSF GRCh37 11 63978082 63978082 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 56 150 0 ENST00000279227.5:c.161-1G>A p.X54_splice ENST00000279227 NM_178443.2 0 +FES UCSF GRCh37 15 91428447 91428447 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 40 103 0 ENST00000328850.3:c.172G>A p.Gly58Ser p.G58S ENST00000328850 NM_002005.3 58 Ggc/Agc 0 +FGF7 UCSF GRCh37 15 49716728 49716728 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 83 175 0 ENST00000267843.4:c.234G>A p.Arg78= p.R78= ENST00000267843 NM_002009.3 78 agG/agA 0 +FGFBP2 UCSF GRCh37 4 15964451 15964451 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 8 81 0 ENST00000259989.6:c.302G>A p.Arg101His p.R101H ENST00000259989 NM_031950.3 101 cGc/cAc 0 +FGGY UCSF GRCh37 1 60133032 60133032 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 130 205 0 ENST00000371218.4:c.1446C>T p.Leu482= p.L482= ENST00000371218 NM_001113411.1 482 ctC/ctT 0 +FHOD1 UCSF GRCh37 16 67265109 67265109 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 28 69 0 ENST00000258201.4:c.2649C>T p.Ala883= p.A883= ENST00000258201 NM_013241.2 883 gcC/gcT 0 +FIBCD1 UCSF GRCh37 9 133799169 133799169 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 30 62 0 ENST00000372338.4:c.811G>A p.Val271Met p.V271M ENST00000372338 NM_032843.4 271 Gtg/Atg 0 +FICD UCSF GRCh37 12 108912289 108912289 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 64 166 0 ENST00000552695.1:c.414C>T p.Asp138= p.D138= ENST00000552695 NM_007076.2 138 gaC/gaT 0 +FIGF UCSF GRCh37 X 15365310 15365310 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 17 129 157 0 ENST00000297904.3:c.914A>G p.Lys305Arg p.K305R ENST00000297904 NM_004469.4 305 aAg/aGg 0 +FIGF UCSF GRCh37 X 15376203 15376203 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 25 139 150 0 ENST00000297904.3:c.414C>T p.Asn138= p.N138= ENST00000297904 NM_004469.4 138 aaC/aaT 0 +FIGNL1 UCSF GRCh37 7 50513387 50513387 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 163 142 226 0 ENST00000419119.1:c.1599A>G p.Thr533= p.T533= ENST00000419119 533 acA/acG 0 +FITM2 UCSF GRCh37 20 42935488 42935488 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 50 109 0 ENST00000396825.3:c.566C>T p.Thr189Ile p.T189I ENST00000396825 NM_001080472.1 189 aCc/aTc 0 +FLG UCSF GRCh37 1 152276776 152276776 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 201 144 319 0 ENST00000368799.1:c.10586C>T p.Pro3529Leu p.P3529L ENST00000368799 NM_002016.1 3529 cCc/cTc 0 +FLJ43860 UCSF GRCh37 8 142517203 142517203 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 9 49 0 ENST00000430863.1:c.47G>A p.Gly16Asp p.G16D ENST00000430863 NM_207414.2 16 gGt/gAt 0 +FLNA UCSF GRCh37 X 153585643 153585643 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 3 33 32 0 ENST00000369850.3:c.4946-1G>A p.X1649_splice ENST00000369850 NM_001110556.1 0 +FLNB UCSF GRCh37 3 58135716 58135716 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec Untested WXS Illumina HiSeq 159 106 247 0 ENST00000490882.1:c.6324C>G p.Asp2108Glu p.D2108E ENST00000490882 NM_001164317.1 2108 gaC/gaG 0 +FLNB UCSF GRCh37 3 58067382 58067382 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 129 90 175 0 ENST00000490882.1:c.666C>T p.His222= p.H222= ENST00000490882 NM_001164317.1 222 caC/caT 0 +FLNC UCSF GRCh37 7 128485171 128485171 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 37 94 0 ENST00000325888.8:c.3652C>T p.Pro1218Ser p.P1218S ENST00000325888 NM_001458.4 1218 Cct/Tct 0 +FLT3LG UCSF GRCh37 19 49983734 49983734 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 15 24 0 ENST00000594009.1:c.660+1G>A p.X220_splice ENST00000594009 NM_001204503.1 0 +FLT4 UCSF GRCh37 5 180057073 180057073 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 21 62 0 ENST00000261937.6:c.546G>A p.Glu182= p.E182= ENST00000261937 NM_182925.4 182 gaG/gaA 0 +FLVCR1 UCSF GRCh37 1 213062556 213062556 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 82 136 0 ENST00000366971.4:c.1482C>T p.Asn494= p.N494= ENST00000366971 NM_014053.3 494 aaC/aaT 0 +FMO4 UCSF GRCh37 1 171310886 171310886 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 39 88 0 ENST00000367749.3:c.1585C>T p.Leu529Phe p.L529F ENST00000367749 NM_002022.1 529 Ctt/Ttt 0 +FMO5 UCSF GRCh37 1 146687361 146687361 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 74 198 0 ENST00000254090.4:c.287C>T p.Ala96Val p.A96V ENST00000254090 NM_001461.3 96 gCc/gTc 0 +FN1 UCSF GRCh37 2 216296570 216296570 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 112 218 0 ENST00000354785.4:c.533C>T p.Thr178Ile p.T178I ENST00000354785 178 aCc/aTc 0 +FNDC1 UCSF GRCh37 6 159642672 159642672 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 69 178 0 ENST00000297267.9:c.710C>T p.Ser237Phe p.S237F ENST00000297267 NM_032532.2 237 tCt/tTt 0 +FNDC1 UCSF GRCh37 6 159653946 159653946 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 45 115 0 ENST00000297267.9:c.2402C>T p.Ala801Val p.A801V ENST00000297267 NM_032532.2 801 gCg/gTg 0 +FOXA2 UCSF GRCh37 20 22564892 22564892 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 20 44 0 ENST00000419308.2:c.25G>A p.Gly9Arg p.G9R ENST00000419308 NM_021784.4 9 Gga/Aga 0 +FOXA2 UCSF GRCh37 20 22563629 22563629 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 63 0 ENST00000419308.2:c.251C>T p.Ala84Val p.A84V ENST00000419308 NM_021784.4 84 gCg/gTg 0 +FOXJ2 UCSF GRCh37 12 8203198 8203198 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 59 152 0 ENST00000162391.3:c.1618G>A p.Ala540Thr p.A540T ENST00000162391 NM_018416.2 540 Gca/Aca 0 +FREM1 UCSF GRCh37 9 14824818 14824818 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 81 190 0 ENST00000422223.2:c.2054C>T p.Pro685Leu p.P685L ENST00000422223 NM_144966.5 685 cCt/cTt 0 +FREM2 UCSF GRCh37 13 39264884 39264884 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 79 194 0 ENST00000280481.7:c.3403G>A p.Ala1135Thr p.A1135T ENST00000280481 NM_207361.4 1135 Gct/Act 0 +FRG2 UCSF GRCh37 4 190946914 190946914 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 62 207 0 ENST00000378763.1:c.639C>T p.Leu213= p.L213= ENST00000378763 NM_001005217.1 213 ctC/ctT 0 +FRMD4B UCSF GRCh37 3 69336917 69336917 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 52 81 0 ENST00000398540.3:c.487G>A p.Ala163Thr p.A163T ENST00000398540 NM_015123.1 163 Gcc/Acc 0 +FRMD5 UCSF GRCh37 15 44180383 44180383 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 49 112 0 ENST00000417257.1:c.874G>A p.Ala292Thr p.A292T ENST00000417257 NM_032892.3 292 Gcc/Acc 0 +FRYL UCSF GRCh37 4 48514613 48514613 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 74 179 0 ENST00000358350.4:c.8030C>T p.Pro2677Leu p.P2677L ENST00000358350 NM_015030.1 2677 cCc/cTc 0 +FSCB UCSF GRCh37 14 44974174 44974174 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 18 88 0 ENST00000340446.4:c.2017C>T p.Pro673Ser p.P673S ENST00000340446 NM_032135.3 673 Cca/Tca 0 +FSIP2 UCSF GRCh37 2 186665922 186665922 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 153 103 252 0 ENST00000343098.5:c.12156G>A p.Gln4052= p.Q4052= ENST00000343098 NM_173651.2 4052 caG/caA 0 +FTCD UCSF GRCh37 21 47575416 47575416 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 29 69 0 ENST00000291670.5:c.22G>A p.Val8Ile p.V8I ENST00000291670 NM_006657.2 8 Gtc/Atc 0 +FTSJD1 UCSF GRCh37 16 71318179 71318179 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 47 122 0 ENST00000338099.5:c.1645G>A p.Val549Ile p.V549I ENST00000338099 549 Gtt/Att 0 +FTSJD1 UCSF GRCh37 16 71318132 71318132 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 45 132 0 ENST00000338099.5:c.1692G>A p.Glu564= p.E564= ENST00000338099 564 gaG/gaA 0 +FUBP3 UCSF GRCh37 9 133506129 133506129 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 50 91 0 ENST00000319725.9:c.1232C>T p.Pro411Leu p.P411L ENST00000319725 NM_003934.1 411 cCc/cTc 0 +FZD6 UCSF GRCh37 8 104337348 104337348 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 137 246 0 ENST00000358755.4:c.1014G>A p.Leu338= p.L338= ENST00000358755 NM_001164616.1 338 ctG/ctA 0 +FZD8 UCSF GRCh37 10 35928730 35928730 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 14 77 0 ENST00000374694.1:c.1628C>T p.Pro543Leu p.P543L ENST00000374694 NM_031866.2 543 cCc/cTc 0 +FZD9 UCSF GRCh37 7 72849769 72849769 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 39 95 0 ENST00000344575.3:c.1432C>T p.Leu478Phe p.L478F ENST00000344575 NM_003508.2 478 Ctt/Ttt 0 +G2E3 UCSF GRCh37 14 31061611 31061611 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 80 117 0 ENST00000206595.6:c.320G>A p.Gly107Glu p.G107E ENST00000206595 NM_017769.3 107 gGa/gAa 0 +G3BP1 UCSF GRCh37 5 151176891 151176891 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 61 148 0 ENST00000394123.3:c.643C>T p.Pro215Ser p.P215S ENST00000394123 215 Cct/Tct 0 +G3BP1 UCSF GRCh37 5 151176792 151176792 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 54 79 0 ENST00000394123.3:c.544G>A p.Asp182Asn p.D182N ENST00000394123 182 Gac/Aac 0 +GABARAP UCSF GRCh37 17 7144983 7144983 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 89 185 0 ENST00000302386.5:c.106G>A p.Ala36Thr p.A36T ENST00000302386 NM_007278.1 36 Gct/Act 0 +GABBR2 UCSF GRCh37 9 101304178 101304178 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 47 120 0 ENST00000259455.2:c.607C>T p.Gln203Ter p.Q203* ENST00000259455 NM_005458.7 203 Caa/Taa 0 +GABPA UCSF GRCh37 21 27136631 27136631 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 62 183 0 ENST00000354828.3:c.913G>A p.Glu305Lys p.E305K ENST00000354828 NM_001197297.1 305 Gaa/Aaa 0 +GABRA4 UCSF GRCh37 4 46930490 46930490 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 134 98 266 1 ENST00000264318.3:c.1417G>A p.Ala473Thr p.A473T ENST00000264318 NM_000809.3 473 Gct/Act 0 +GABRB1 UCSF GRCh37 4 47163377 47163377 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 170 144 306 0 ENST00000295454.3:c.352G>A p.Val118Ile p.V118I ENST00000295454 NM_000812.3 118 Gta/Ata 0 +GABRB3 UCSF GRCh37 15 26812804 26812804 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 58 160 0 ENST00000311550.5:c.759C>T p.Pro253= p.P253= ENST00000311550 NM_000814.5 253 ccC/ccT 0 +GABRR3 UCSF GRCh37 3 97720581 97720581 + non_coding_transcript_exon_variant RNA SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 87 63 130 0 ENST00000470589.1:n.532T>C *178* ENST00000470589 0 +GAL3ST2 UCSF GRCh37 2 242743054 242743054 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 7 15 0 ENST00000192314.6:c.670G>A p.Val224Met p.V224M ENST00000192314 NM_022134.2 224 Gtg/Atg 0 +GALNT1 UCSF GRCh37 18 33271053 33271053 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 177 145 263 0 ENST00000269195.5:c.1056C>T p.Tyr352= p.Y352= ENST00000269195 NM_020474.3 352 taC/taT 0 +GALNT4 UCSF GRCh37 12 89917070 89917070 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 114 216 0 ENST00000529983.2:c.1257G>A p.Leu419= p.L419= ENST00000529983 NM_003774.4 419 ttG/ttA 0 +GALNT5 UCSF GRCh37 2 158115847 158115847 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 77 212 0 ENST00000259056.4:c.1253G>A p.Ser418Asn p.S418N ENST00000259056 NM_014568.1 418 aGt/aAt 0 +GALNT7 UCSF GRCh37 4 174225262 174225262 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 60 147 0 ENST00000265000.4:c.1382C>T p.Thr461Ile p.T461I ENST00000265000 NM_017423.2 461 aCt/aTt 0 +GAPDHS UCSF GRCh37 19 36034723 36034723 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 29 65 0 ENST00000222286.4:c.1050G>A p.Glu350= p.E350= ENST00000222286 NM_014364.4 350 gaG/gaA 0 +GAPVD1 UCSF GRCh37 9 128099513 128099513 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 57 133 0 ENST00000394105.2:c.2601G>A p.Val867= p.V867= ENST00000394105 NM_015635.2 867 gtG/gtA 0 +GARNL3 UCSF GRCh37 9 130098462 130098462 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 51 137 0 ENST00000373387.4:c.929G>A p.Gly310Glu p.G310E ENST00000373387 NM_032293.4 310 gGa/gAa 0 +GARNL3 UCSF GRCh37 9 130149546 130149546 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 61 130 0 ENST00000373387.4:c.2463C>T p.Ala821= p.A821= ENST00000373387 NM_032293.4 821 gcC/gcT 0 +GAS6 UCSF GRCh37 13 114542772 114542772 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 55 129 0 ENST00000327773.6:c.395C>T p.Ala132Val p.A132V ENST00000327773 NM_000820.2 132 gCc/gTc 0 +GBP3 UCSF GRCh37 1 89476628 89476628 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 183 186 0 ENST00000370481.4:c.1321C>T p.Leu441= p.L441= ENST00000370481 NM_018284.2 441 Ctg/Ttg 0 +GDAP2 UCSF GRCh37 1 118420712 118420712 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 57 130 0 ENST00000369443.5:c.1365G>A p.Val455= p.V455= ENST00000369443 NM_017686.3 455 gtG/gtA 0 +GDF15 UCSF GRCh37 19 18499125 18499125 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 14 33 0 ENST00000252809.3:c.307C>T p.Leu103= p.L103= ENST00000252809 NM_004864.2 103 Ctg/Ttg 0 +GDF2 UCSF GRCh37 10 48416610 48416610 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 26 18 56 0 ENST00000249598.1:c.84G>A p.Trp28Ter p.W28* ENST00000249598 NM_016204.1 28 tgG/tgA 0 +GFM2 UCSF GRCh37 5 74034354 74034354 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 62 161 0 ENST00000296805.3:c.1193C>T p.Ala398Val p.A398V ENST00000296805 NM_032380.4 398 gCc/gTc 0 +GGA1 UCSF GRCh37 22 38028003 38028003 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 29 88 0 ENST00000343632.4:c.1529G>A p.Ser510Asn p.S510N ENST00000343632 NM_013365.4 510 aGc/aAc 0 +GGA3 UCSF GRCh37 17 73238537 73238537 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 143 112 232 0 ENST00000245541.6:c.627G>A p.Gln209= p.Q209= ENST00000245541 NM_138619.2 209 caG/caA 0 +GGCX UCSF GRCh37 2 85778691 85778691 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 77 185 0 ENST00000233838.4:c.1652C>T p.Thr551Ile p.T551I ENST00000233838 NM_000821.5 551 aCt/aTt 0 +GGCX UCSF GRCh37 2 85780478 85780478 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 83 184 0 ENST00000233838.4:c.1032G>A p.Val344= p.V344= ENST00000233838 NM_000821.5 344 gtG/gtA 0 +GHDC UCSF GRCh37 17 40344541 40344541 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 83 177 0 ENST00000301671.8:c.607G>A p.Ala203Thr p.A203T ENST00000301671 203 Gct/Act 0 +GHDC UCSF GRCh37 17 40342239 40342239 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 82 175 0 ENST00000301671.8:c.1338G>A p.Arg446= p.R446= ENST00000301671 446 agG/agA 0 +GIMAP8 UCSF GRCh37 7 150171727 150171727 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 58 132 0 ENST00000307271.3:c.1309+1G>A p.X437_splice ENST00000307271 NM_175571.2 0 +GIP UCSF GRCh37 17 47038273 47038273 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 10 21 0 ENST00000357424.2:c.427G>A p.Asp143Asn p.D143N ENST00000357424 NM_004123.2 143 Gat/Aat 0 +GIT2 UCSF GRCh37 12 110405292 110405292 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 63 136 0 ENST00000355312.3:c.735G>A p.Gln245= p.Q245= ENST00000355312 NM_057169.3 245 caG/caA 0 +GJA5 UCSF GRCh37 1 147230420 147230420 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 89 186 0 ENST00000271348.2:c.927G>A p.Gly309= p.G309= ENST00000271348 NM_005266.6 309 ggG/ggA 0 +GJB6 UCSF GRCh37 13 20796987 20796987 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 56 130 0 ENST00000356192.6:c.633C>T p.Cys211= p.C211= ENST00000356192 NM_001110219.2 211 tgC/tgT 0 +GLI2 UCSF GRCh37 2 121747119 121747119 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 15 31 0 ENST00000452319.1:c.3629G>A p.Gly1210Glu p.G1210E ENST00000452319 1210 gGa/gAa 0 +GLOD5 UCSF GRCh37 X 48631750 48631750 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 125 110 0 ENST00000303227.6:c.382G>A p.Gly128Arg p.G128R ENST00000303227 NM_001080489.2 128 Ggg/Agg 0 +GLS2 UCSF GRCh37 12 56866533 56866533 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 90 199 0 ENST00000311966.4:c.1452C>T p.Asn484= p.N484= ENST00000311966 NM_001280797.1 484 aaC/aaT 0 +GLT25D1 UCSF GRCh37 19 17691630 17691630 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 23 83 0 ENST00000252599.4:c.1517C>T p.Ala506Val p.A506V ENST00000252599 NM_024656.2 506 gCc/gTc 0 +GLT25D1 UCSF GRCh37 19 17688209 17688209 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 7 9 0 ENST00000252599.4:c.1066G>A p.Glu356Lys p.E356K ENST00000252599 NM_024656.2 356 Gag/Aag 0 +GLT6D1 UCSF GRCh37 9 138516249 138516249 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 59 119 0 ENST00000371763.1:c.525C>T p.Asn175= p.N175= ENST00000371763 NM_182974.2 175 aaC/aaT 0 +GNAI3 UCSF GRCh37 1 110116530 110116530 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 83 182 0 ENST00000369851.4:c.174G>A p.Glu58= p.E58= ENST00000369851 NM_006496.3 58 gaG/gaA 0 +GNB2 UCSF GRCh37 7 100275839 100275839 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 96 161 0 ENST00000303210.4:c.616G>A p.Ala206Thr p.A206T ENST00000303210 NM_005273.3 206 Gcc/Acc 0 +GNG2 UCSF GRCh37 14 52433376 52433376 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 94 216 0 ENST00000335281.4:c.187G>A p.Glu63Lys p.E63K ENST00000335281 NM_001243774.1 63 Gag/Aag 0 +GNL1 UCSF GRCh37 6 30514932 30514932 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 50 124 0 ENST00000376621.3:c.1398C>T p.Asp466= p.D466= ENST00000376621 NM_005275.3 466 gaC/gaT 0 +GNL3L UCSF GRCh37 X 54570681 54570681 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 4 19 33 0 ENST00000336470.4:c.552G>A p.Glu184= p.E184= ENST00000336470 NM_019067.5 184 gaG/gaA 0 +GNPAT UCSF GRCh37 1 231386751 231386751 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 119 97 178 0 ENST00000366647.4:c.123G>A p.Glu41= p.E41= ENST00000366647 NM_014236.3 41 gaG/gaA 0 +GON4L UCSF GRCh37 1 155735038 155735038 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 151 121 263 0 ENST00000437809.1:c.4226G>A p.Gly1409Glu p.G1409E ENST00000437809 1409 gGa/gAa 0 +GOT1L1 UCSF GRCh37 8 37796328 37796328 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 86 192 0 ENST00000307599.4:c.187G>A p.Asp63Asn p.D63N ENST00000307599 NM_152413.2 63 Gat/Aat 0 +GP1BA UCSF GRCh37 17 4836177 4836177 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 95 187 0 ENST00000329125.5:c.278C>T p.Pro93Leu p.P93L ENST00000329125 NM_000173.5 93 cCa/cTa 0 +GPAA1 UCSF GRCh37 8 145138941 145138941 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 70 104 0 ENST00000355091.4:c.614C>T p.Thr205Ile p.T205I ENST00000355091 NM_003801.3 205 aCt/aTt 0 +GPATCH1 UCSF GRCh37 19 33608917 33608917 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 56 128 0 ENST00000170564.2:c.2383G>A p.Asp795Asn p.D795N ENST00000170564 NM_018025.2 795 Gac/Aac 0 +GPATCH3 UCSF GRCh37 1 27217646 27217646 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 43 79 0 ENST00000361720.5:c.1433C>T p.Ser478Phe p.S478F ENST00000361720 NM_022078.2 478 tCc/tTc 0 +GPC5 UCSF GRCh37 13 92345775 92345775 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 34 113 0 ENST00000377067.3:c.660G>A p.Leu220= p.L220= ENST00000377067 NM_004466.4 220 ctG/ctA 0 +GPR108 UCSF GRCh37 19 6734315 6734315 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 15 36 0 ENST00000264080.7:c.378C>T p.Val126= p.V126= ENST00000264080 NM_001080452.1 126 gtC/gtT 0 +GPR112 UCSF GRCh37 X 135432197 135432197 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 106 112 0 ENST00000394143.1:c.6332C>T p.Thr2111Ile p.T2111I ENST00000394143 NM_153834.3 2111 aCc/aTc 0 +GPR113 UCSF GRCh37 2 26534502 26534502 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 73 101 0 ENST00000311519.1:c.2094C>T p.Ser698= p.S698= ENST00000311519 NM_001145168.1 698 agC/agT 0 +GPR116 UCSF GRCh37 6 46839599 46839599 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 126 99 197 0 ENST00000283296.7:c.1392A>G p.Lys464= p.K464= ENST00000283296 NM_001098518.1 464 aaA/aaG 0 +GPR125 UCSF GRCh37 4 22446699 22446699 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 45 117 0 ENST00000334304.5:c.603G>A p.Trp201Ter p.W201* ENST00000334304 NM_145290.3 201 tgG/tgA 0 +GPR158 UCSF GRCh37 10 25701324 25701324 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 338 108 265 0 ENST00000376351.3:c.1257C>T p.Ala419= p.A419= ENST00000376351 NM_020752.2 419 gcC/gcT 0 +GPR179 UCSF GRCh37 17 36499172 36499172 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 62 143 0 ENST00000342292.4:c.501C>T p.Thr167= p.T167= ENST00000342292 NM_001004334.2 167 acC/acT 0 +GPR26 UCSF GRCh37 10 125426578 125426578 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 9 31 0 ENST00000284674.1:c.655G>T p.Asp219Tyr p.D219Y ENST00000284674 NM_153442.3 219 Gac/Tac 0 +GPR32 UCSF GRCh37 19 51274536 51274536 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 54 120 0 ENST00000270590.4:c.679G>A p.Gly227Arg p.G227R ENST00000270590 NM_001506.2 227 Ggg/Agg 0 +GPR35 UCSF GRCh37 2 241569429 241569429 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 43 96 0 ENST00000438013.2:c.153G>A p.Lys51= p.K51= ENST00000438013 51 aaG/aaA 0 +GPR37 UCSF GRCh37 7 124404799 124404799 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 26 51 0 ENST00000303921.2:c.232G>A p.Ala78Thr p.A78T ENST00000303921 NM_005302.3 78 Gca/Aca 0 +GPR56 UCSF GRCh37 16 57687213 57687213 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 17 41 0 ENST00000388812.4:c.586G>A p.Ala196Thr p.A196T ENST00000388812 196 Gcc/Acc 0 +GPR56 UCSF GRCh37 16 57693441 57693441 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 48 110 0 ENST00000388812.4:c.1421G>A p.Gly474Asp p.G474D ENST00000388812 474 gGc/gAc 0 +GPR64 UCSF GRCh37 X 19028836 19028836 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 115 132 0 ENST00000379869.3:c.1160C>T p.Ala387Val p.A387V ENST00000379869 NM_001079858.2 387 gCt/gTt 0 +GPR82 UCSF GRCh37 X 41586742 41586742 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 96 97 0 ENST00000302548.4:c.463C>T p.Leu155= p.L155= ENST00000302548 NM_080817.4 155 Cta/Tta 0 +GPR98 UCSF GRCh37 5 90083954 90083954 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 140 94 198 0 ENST00000405460.2:c.13720G>A p.Asp4574Asn p.D4574N ENST00000405460 NM_032119.3 4574 Gac/Aac 0 +GPRIN1 UCSF GRCh37 5 176025149 176025149 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 90 193 0 ENST00000303991.4:c.1687C>T p.Pro563Ser p.P563S ENST00000303991 NM_052899.2 563 Ccc/Tcc 0 +GPS1 UCSF GRCh37 17 80010317 80010317 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 19 34 0 ENST00000392358.2:c.135C>T p.Ala45= p.A45= ENST00000392358 NM_212492.1 45 gcC/gcT 0 +GPSM1 UCSF GRCh37 9 139252516 139252516 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 19 51 0 ENST00000440944.1:c.1872G>A p.Arg624= p.R624= ENST00000440944 NM_001145638.2 624 cgG/cgA 0 +GPX3 UCSF GRCh37 5 150407620 150407620 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 23 72 0 ENST00000388825.4:c.610G>A p.Val204Ile p.V204I ENST00000388825 NM_002084.3 204 Gtc/Atc 0 +GPX8 UCSF GRCh37 5 54456129 54456129 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 81 189 0 ENST00000503787.1:c.109C>T p.Leu37= p.L37= ENST00000503787 NM_001008397.2 37 Cta/Tta 0 +GREB1L UCSF GRCh37 18 18983857 18983857 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 175 141 316 0 ENST00000580732.2:c.734C>T p.Ala245Val p.A245V ENST00000580732 245 gCt/gTt 0 +GREB1L UCSF GRCh37 18 19080545 19080545 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 19 42 0 ENST00000580732.2:c.4014C>T p.Phe1338= p.F1338= ENST00000580732 1338 ttC/ttT 0 +GRID1 UCSF GRCh37 10 87966175 87966175 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 44 99 0 ENST00000327946.7:c.466C>T p.Leu156= p.L156= ENST00000327946 NM_017551.2 156 Ctg/Ttg 0 +GRIK5 UCSF GRCh37 19 42558519 42558519 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 35 82 0 ENST00000262895.3:c.1009G>A p.Ala337Thr p.A337T ENST00000262895 NM_002088.4 337 Gcc/Acc 0 +GRIN2A UCSF GRCh37 16 9858036 9858036 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 231 95 200 0 ENST00000330684.3:c.3365G>A p.Gly1122Asp p.G1122D ENST00000330684 NM_001134407.1 1122 gGt/gAt 0 +GRIN2A UCSF GRCh37 16 9923338 9923338 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 206 80 173 0 ENST00000330684.3:c.1949C>T p.Ala650Val p.A650V ENST00000330684 NM_001134407.1 650 gCt/gTt 0 +GRIN2C UCSF GRCh37 17 72848181 72848181 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 10 16 0 ENST00000293190.5:c.969C>T p.Pro323= p.P323= ENST00000293190 NM_000835.4 323 ccC/ccT 0 +GRIN3A UCSF GRCh37 9 104499668 104499668 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 43 123 0 ENST00000361820.3:c.594C>T p.Ala198= p.A198= ENST00000361820 NM_133445.2 198 gcC/gcT 0 +GRK6 UCSF GRCh37 5 176862108 176862108 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 19 54 0 ENST00000528793.1:c.1043C>T p.Thr348Ile p.T348I ENST00000528793 348 aCc/aTc 0 +GRK7 UCSF GRCh37 3 141497563 141497563 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 49 104 0 ENST00000264952.2:c.437C>T p.Ala146Val p.A146V ENST00000264952 NM_139209.2 146 gCa/gTa 0 +GSDMD UCSF GRCh37 8 144642028 144642028 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 23 56 0 ENST00000526406.1:c.299G>A p.Gly100Glu p.G100E ENST00000526406 NM_001166237.1 100 gGa/gAa 0 +GTDC1 UCSF GRCh37 2 144714815 144714815 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 63 153 0 ENST00000392869.2:c.1077C>T p.Cys359= p.C359= ENST00000392869 NM_001284234.1 359 tgC/tgT 0 +GTF2B UCSF GRCh37 1 89353037 89353037 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 171 129 260 0 ENST00000370500.5:c.31C>T p.Pro11Ser p.P11S ENST00000370500 NM_001514.5 11 Cca/Tca 0 +GTF2E2 UCSF GRCh37 8 30437797 30437797 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 183 125 284 0 ENST00000355904.4:c.759+1G>A p.X253_splice ENST00000355904 NM_002095.4 0 +GTF2F1 UCSF GRCh37 19 6380678 6380678 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 43 90 0 ENST00000394456.5:c.1255G>A p.Ala419Thr p.A419T ENST00000394456 NM_002096.2 419 Gca/Aca 0 +GTF2IRD1 UCSF GRCh37 7 73973225 73973225 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 42 95 0 ENST00000455841.2:c.2238C>T p.Val746= p.V746= ENST00000455841 NM_001199207.1 746 gtC/gtT 0 +GTF3C2 UCSF GRCh37 2 27551736 27551736 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 54 93 0 ENST00000359541.2:c.2102C>T p.Thr701Ile p.T701I ENST00000359541 701 aCt/aTt 0 +GYG1 UCSF GRCh37 3 148744574 148744574 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 61 152 0 ENST00000345003.4:c.907C>T p.Leu303= p.L303= ENST00000345003 NM_004130.3 303 Ctg/Ttg 0 +GYS1 UCSF GRCh37 19 49494637 49494637 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 93 159 0 ENST00000323798.3:c.222G>A p.Arg74= p.R74= ENST00000323798 NM_002103.4 74 agG/agA 0 +GZMA UCSF GRCh37 5 54404196 54404196 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 69 165 0 ENST00000274306.6:c.601C>T p.Leu201Phe p.L201F ENST00000274306 NM_006144.3 201 Ctc/Ttc 0 +GZMH UCSF GRCh37 14 25076612 25076612 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 26 71 0 ENST00000216338.4:c.340C>T p.Leu114= p.L114= ENST00000216338 NM_033423.4 114 Ctg/Ttg 0 +HAS1 UCSF GRCh37 19 52217087 52217087 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 13 30 0 ENST00000222115.1:c.1330G>A p.Ala444Thr p.A444T ENST00000222115 NM_001523.2 444 Gcc/Acc 0 +HAT1 UCSF GRCh37 2 172803277 172803277 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 74 158 0 ENST00000264108.4:c.162G>A p.Glu54= p.E54= ENST00000264108 NM_003642.3 54 gaG/gaA 0 +HBQ1 UCSF GRCh37 16 230818 230818 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 7 12 0 ENST00000199708.2:c.249G>A p.Ala83= p.A83= ENST00000199708 NM_005331.4 83 gcG/gcA 0 +HCK UCSF GRCh37 20 30674508 30674508 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 31 72 0 ENST00000375852.2:c.913G>A p.Glu305Lys p.E305K ENST00000375852 305 Gag/Aag 0 +HCN4 UCSF GRCh37 15 73617356 73617356 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 64 111 0 ENST00000261917.3:c.1918G>A p.Val640Ile p.V640I ENST00000261917 NM_005477.2 640 Gtc/Atc 0 +HCRTR1 UCSF GRCh37 1 32087185 32087185 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 65 160 0 ENST00000403528.2:c.730G>A p.Gly244Ser p.G244S ENST00000403528 NM_001525.2 244 Ggc/Agc 0 +HDAC3 UCSF GRCh37 5 141004869 141004869 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 207 138 295 0 ENST00000305264.3:c.1123G>A p.Val375Ile p.V375I ENST00000305264 NM_003883.3 375 Gtc/Atc 0 +HDGFRP2 UCSF GRCh37 19 4499544 4499544 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 19 53 0 ENST00000301284.4:c.1632C>T p.Thr544= p.T544= ENST00000301284 NM_001001520.1 544 acC/acT 0 +HEATR1 UCSF GRCh37 1 236744649 236744649 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 196 124 244 0 ENST00000366582.3:c.2628C>T p.Ser876= p.S876= ENST00000366582 NM_018072.5 876 agC/agT 0 +HEATR5B UCSF GRCh37 2 37235830 37235830 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 95 201 0 ENST00000233099.5:c.4446C>T p.Arg1482= p.R1482= ENST00000233099 NM_019024.1 1482 cgC/cgT 0 +HEATR8 UCSF GRCh37 1 55145099 55145099 + missense_variant,NMD_transcript_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 23 73 0 ENST00000414150.2:c.2213G>A p.Arg738Lys p.R738K ENST00000414150 738 aGg/aAg 0 +HEG1 UCSF GRCh37 3 124731715 124731715 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 161 130 305 0 ENST00000311127.4:c.2708G>A p.Arg903Lys p.R903K ENST00000311127 NM_020733.1 903 aGg/aAg 0 +HEG1 UCSF GRCh37 3 124746251 124746251 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 131 73 162 0 ENST00000311127.4:c.711G>A p.Glu237= p.E237= ENST00000311127 NM_020733.1 237 gaG/gaA 0 +HEG1 UCSF GRCh37 3 124692647 124692647 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 185 158 283 0 ENST00000311127.4:c.3924C>T p.Gly1308= p.G1308= ENST00000311127 NM_020733.1 1308 ggC/ggT 0 +HELZ UCSF GRCh37 17 65144795 65144795 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 186 106 290 0 ENST00000358691.5:c.2511G>A p.Glu837= p.E837= ENST00000358691 NM_014877.3 837 gaG/gaA 0 +HEMGN UCSF GRCh37 9 100693034 100693034 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 200 191 371 0 ENST00000259456.3:c.643C>T p.Pro215Ser p.P215S ENST00000259456 NM_018437.4 215 Cct/Tct 0 +HEMGN UCSF GRCh37 9 100692353 100692353 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 144 124 229 0 ENST00000259456.3:c.1324C>T p.Gln442Ter p.Q442* ENST00000259456 NM_018437.4 442 Cag/Tag 0 +HEPACAM UCSF GRCh37 11 124793894 124793894 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 18 40 0 ENST00000298251.4:c.440G>A p.Arg147Lys p.R147K ENST00000298251 NM_152722.4 147 aGg/aAg 0 +HERC2 UCSF GRCh37 15 28412840 28412840 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 103 203 0 ENST00000261609.7:c.10547C>T p.Thr3516Ile p.T3516I ENST00000261609 NM_004667.5 3516 aCc/aTc 0 +HERC2 UCSF GRCh37 15 28518093 28518093 + synonymous_variant Silent SNP C C T snp132_rs59154112 P18_Rec Untested WXS Illumina HiSeq 73 32 83 0 ENST00000261609.7:c.858G>A p.Gln286= p.Q286= ENST00000261609 NM_004667.5 286 caG/caA 0 +HERC2 UCSF GRCh37 15 28482229 28482229 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 94 284 0 ENST00000261609.7:c.3883C>T p.Leu1295= p.L1295= ENST00000261609 NM_004667.5 1295 Ctg/Ttg 0 +HESX1 UCSF GRCh37 3 57232851 57232851 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 287 188 402 0 ENST00000295934.3:c.287G>A p.Arg96Lys p.R96K ENST00000295934 NM_003865.2 96 aGa/aAa 0 +HFM1 UCSF GRCh37 1 91788756 91788756 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 96 242 0 ENST00000370425.3:c.2428G>A p.Val810Ile p.V810I ENST00000370425 NM_001017975.3 810 Gtt/Att 0 +HGF UCSF GRCh37 7 81374400 81374400 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 54 135 0 ENST00000222390.5:c.662G>A p.Gly221Asp p.G221D ENST00000222390 NM_000601.4 221 gGt/gAt 0 +HHIP UCSF GRCh37 4 145659036 145659036 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 121 232 0 ENST00000296575.3:c.2030C>T p.Thr677Ile p.T677I ENST00000296575 NM_022475.2 677 aCc/aTc 0 +HIATL1 UCSF GRCh37 9 97221478 97221478 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 86 176 0 ENST00000375344.3:c.1305G>A p.Gly435= p.G435= ENST00000375344 NM_032558.2 435 ggG/ggA 0 +HIPK2 UCSF GRCh37 7 139257685 139257685 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 14 25 0 ENST00000406875.3:c.3585C>T p.Tyr1195= p.Y1195= ENST00000406875 NM_022740.4 1195 taC/taT 0 +HIVEP1 UCSF GRCh37 6 12122847 12122847 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 40 112 0 ENST00000379388.2:c.2819T>A p.Leu940Gln p.L940Q ENST00000379388 NM_002114.2 940 cTg/cAg 0 +HIVEP3 UCSF GRCh37 1 42049788 42049788 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 55 119 0 ENST00000372583.1:c.681C>T p.Phe227= p.F227= ENST00000372583 NM_024503.4 227 ttC/ttT 0 +HKDC1 UCSF GRCh37 10 71018671 71018671 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 44 95 0 ENST00000354624.5:c.2172C>T p.Tyr724= p.Y724= ENST00000354624 NM_025130.3 724 taC/taT 0 +HLA-C UCSF GRCh37 6 31238956 31238956 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 10 94 0 ENST00000376228.5:c.513G>A p.Leu171= p.L171= ENST00000376228 NM_002117.5 171 ttG/ttA 0 +HLA-DQA1 UCSF GRCh37 6 32609823 32609823 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 18 38 52 0 ENST00000343139.5:c.406G>A p.Asp136Asn p.D136N ENST00000343139 NM_002122.3 136 Gac/Aac 0 +HLA-DQA2 UCSF GRCh37 6 32713642 32713642 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 276 45 352 0 ENST00000374940.3:c.406G>A p.Asp136Asn p.D136N ENST00000374940 NM_020056.4 136 Gac/Aac 0 +HLA-DRA UCSF GRCh37 6 32411128 32411128 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 111 207 0 ENST00000395388.2:c.495G>A p.Arg165= p.R165= ENST00000395388 NM_019111.4 165 agG/agA 0 +HLA-DRB5 UCSF GRCh37 6 32489786 32489786 + missense_variant Missense_Mutation SNP T T G 1000g2010nov_all_0.101,1000g2011may_all_0.1594,snp132_rs41541218 P18_Rec Untested WXS Illumina HiSeq 44 8 58 1 ENST00000374975.3:c.266A>C p.Tyr89Ser p.Y89S ENST00000374975 NM_002125.3 89 tAc/tCc 0 +HLA-DRB5 UCSF GRCh37 6 32489806 32489806 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.029,snp132_rs1059349 P18_Rec Untested WXS Illumina HiSeq 56 8 64 1 ENST00000374975.3:c.246G>A p.Leu82= p.L82= ENST00000374975 NM_002125.3 82 ctG/ctA 0 +HMCN1 UCSF GRCh37 1 186026477 186026477 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 86 204 0 ENST00000271588.4:c.7256C>T p.Thr2419Ile p.T2419I ENST00000271588 NM_031935.2 2419 aCc/aTc 0 +HMCN1 UCSF GRCh37 1 186136014 186136014 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 68 149 0 ENST00000271588.4:c.15514C>T p.Arg5172Cys p.R5172C ENST00000271588 NM_031935.2 5172 Cgc/Tgc 0 +HMCN1 UCSF GRCh37 1 186084079 186084079 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 167 139 266 0 ENST00000271588.4:c.11404+1G>A p.X3802_splice ENST00000271588 NM_031935.2 0 +HMGB1 UCSF GRCh37 13 31036689 31036689 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 218 118 345 0 ENST00000405805.1:c.457G>A p.Glu153Lys p.E153K ENST00000405805 153 Gaa/Aaa 0 +HMX2 UCSF GRCh37 10 124909357 124909357 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 26 43 0 ENST00000339992.3:c.540C>T p.Ala180= p.A180= ENST00000339992 NM_005519.1 180 gcC/gcT 0 +HN1L UCSF GRCh37 16 1741846 1741846 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 88 84 0 ENST00000248098.3:c.196G>A p.Gly66Ser p.G66S ENST00000248098 NM_144570.2 66 Ggt/Agt 0 +HNF1A UCSF GRCh37 12 121432194 121432194 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec Untested WXS Illumina HiSeq 10 12 23 0 ENST00000257555.6:c.941C>G p.Pro314Arg p.P314R ENST00000257555 314 cCc/cGc 0 +HNRNPC UCSF GRCh37 14 21699190 21699190 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 155 113 237 0 ENST00000320084.7:c.283G>A p.Ala95Thr p.A95T ENST00000320084 NM_001077442.1 95 Gca/Aca 0 +HNRNPR UCSF GRCh37 1 23640128 23640128 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 65 180 0 ENST00000374616.3:c.1094C>T p.Ser365Phe p.S365F ENST00000374616 365 tCt/tTt 0 +HNRNPR UCSF GRCh37 1 23664278 23664278 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 150 83 182 0 ENST00000374616.3:c.353C>T p.Ser118Phe p.S118F ENST00000374616 118 tCc/tTc 0 +HNRNPU UCSF GRCh37 1 245021312 245021312 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 52 100 0 ENST00000283179.9:c.1494+1G>A p.X498_splice ENST00000283179 0 +HOMER1 UCSF GRCh37 5 78746835 78746835 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 60 140 0 ENST00000334082.6:c.272C>T p.Ser91Phe p.S91F ENST00000334082 NM_004272.4 91 tCc/tTc 0 +HOXA11 UCSF GRCh37 7 27224621 27224621 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 51 134 0 ENST00000006015.3:c.143C>T p.Ser48Phe p.S48F ENST00000006015 NM_005523.5 48 tCc/tTc 0 +HOXA3 UCSF GRCh37 7 27147692 27147692 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 35 81 0 ENST00000396352.4:c.1174G>A p.Ala392Thr p.A392T ENST00000396352 NM_030661.4 392 Gcc/Acc 0 +HOXD3 UCSF GRCh37 2 177036434 177036434 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 75 45 146 0 ENST00000468418.3:c.731A>G p.Asn244Ser p.N244S ENST00000468418 244 aAc/aGc 0 +HOXD9 UCSF GRCh37 2 176988780 176988780 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 148 98 224 0 ENST00000249499.6:c.936G>A p.Arg312= p.R312= ENST00000249499 NM_014213.3 312 cgG/cgA 0 +HP1BP3 UCSF GRCh37 1 21097494 21097494 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 82 134 0 ENST00000312239.5:c.583G>A p.Glu195Lys p.E195K ENST00000312239 NM_016287.3 195 Gag/Aag 0 +HPD UCSF GRCh37 12 122281701 122281701 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 68 124 0 ENST00000289004.4:c.869C>T p.Ser290Phe p.S290F ENST00000289004 NM_002150.2 290 tCt/tTt 0 +HPN UCSF GRCh37 19 35556509 35556509 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 60 108 0 ENST00000262626.2:c.974C>T p.Ala325Val p.A325V ENST00000262626 NM_182983.2 325 gCt/gTt 0 +HS3ST5 UCSF GRCh37 6 114378655 114378655 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 61 143 0 ENST00000312719.5:c.807G>A p.Val269= p.V269= ENST00000312719 269 gtG/gtA 0 +HS6ST1 UCSF GRCh37 2 129026197 129026197 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 22 94 0 ENST00000259241.6:c.775C>T p.Leu259= p.L259= ENST00000259241 NM_004807.2 259 Ctg/Ttg 0 +HSD17B1 UCSF GRCh37 17 40706695 40706695 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 27 24 47 0 ENST00000585807.1:c.726C>T p.Leu242= p.L242= ENST00000585807 NM_000413.2 242 ctC/ctT 0 +HSD3B1 UCSF GRCh37 1 120057019 120057019 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 108 210 0 ENST00000369413.3:c.873G>A p.Met291Ile p.M291I ENST00000369413 291 atG/atA 0 +HSDL2 UCSF GRCh37 9 115179137 115179137 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 50 106 0 ENST00000398805.3:c.412C>T p.Pro138Ser p.P138S ENST00000398805 NM_032303.4 138 Cct/Tct 0 +HSF4 UCSF GRCh37 16 67202963 67202963 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 28 82 0 ENST00000264009.8:c.1213C>T p.Arg405Ter p.R405* ENST00000264009 NM_001040667.2 405 Cga/Tga 0 +HSPA1A UCSF GRCh37 6 31785229 31785229 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 41 121 0 ENST00000375651.5:c.1696G>A p.Asp566Asn p.D566N ENST00000375651 NM_005345.5 566 Gac/Aac 0 +HSPA2 UCSF GRCh37 14 65008270 65008270 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 54 112 0 ENST00000247207.6:c.703G>A p.Asp235Asn p.D235N ENST00000247207 NM_021979.3 235 Gac/Aac 0 +HSPA6 UCSF GRCh37 1 161495582 161495582 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 19 93 0 ENST00000309758.4:c.1134G>A p.Gln378= p.Q378= ENST00000309758 NM_002155.3 378 caG/caA 0 +HSPBAP1 UCSF GRCh37 3 122459361 122459361 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 100 236 0 ENST00000306103.2:c.1298G>A p.Arg433Lys p.R433K ENST00000306103 NM_024610.5 433 aGa/aAa 0 +HSPG2 UCSF GRCh37 1 22217131 22217131 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 64 164 0 ENST00000374695.3:c.301G>A p.Glu101Lys p.E101K ENST00000374695 NM_005529.5 101 Gag/Aag 0 +HTR3D UCSF GRCh37 3 183754189 183754189 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 50 102 0 ENST00000382489.3:c.407T>A p.Met136Lys p.M136K ENST00000382489 NM_001163646.1 136 aTg/aAg 0 +HYDIN UCSF GRCh37 16 70929894 70929894 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 286 56 310 0 ENST00000393567.2:c.9138C>T p.Thr3046= p.T3046= ENST00000393567 NM_001270974.1 3046 acC/acT 0 +HYDIN UCSF GRCh37 16 71113831 71113831 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 152 27 159 0 ENST00000393567.2:c.1695C>T p.Phe565= p.F565= ENST00000393567 NM_001270974.1 565 ttC/ttT 0 +IARS2 UCSF GRCh37 1 220267700 220267700 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 10 33 0 ENST00000302637.5:c.142G>A p.Ala48Thr p.A48T ENST00000302637 NM_018060.3 48 Gcc/Acc 0 +IARS2 UCSF GRCh37 1 220315250 220315250 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 107 232 0 ENST00000302637.5:c.2520C>T p.His840= p.H840= ENST00000302637 NM_018060.3 840 caC/caT 0 +ICAM1 UCSF GRCh37 19 10395087 10395087 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 42 118 0 ENST00000264832.3:c.934G>A p.Ala312Thr p.A312T ENST00000264832 NM_000201.2 312 Gcg/Acg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 54 155 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFIT1B UCSF GRCh37 10 91143734 91143734 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 207 179 342 0 ENST00000371809.3:c.664C>T p.Leu222Phe p.L222F ENST00000371809 NM_001010987.2 222 Ctc/Ttc 0 +IFRD2 UCSF GRCh37 3 50326905 50326905 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 21 59 0 ENST00000429673.2:c.944G>A p.Ser315Asn p.S315N ENST00000429673 315 aGc/aAc 0 +IFT122 UCSF GRCh37 3 129197029 129197029 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 44 100 0 ENST00000296266.3:c.1471G>A p.Val491Met p.V491M ENST00000296266 NM_052985.3 491 Gtg/Atg 0 +IGF2BP1 UCSF GRCh37 17 47122362 47122362 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 66 205 0 ENST00000290341.3:c.1330C>T p.Pro444Ser p.P444S ENST00000290341 NM_006546.3 444 Ccc/Tcc 0 +IGF2R UCSF GRCh37 6 160493852 160493852 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 66 167 0 ENST00000356956.1:c.4626C>T p.Tyr1542= p.Y1542= ENST00000356956 NM_000876.2 1542 taC/taT 0 +IGF2R UCSF GRCh37 6 160467530 160467530 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 36 73 0 ENST00000356956.1:c.1904G>A p.Gly635Glu p.G635E ENST00000356956 NM_000876.2 635 gGg/gAg 0 +IGFN1 UCSF GRCh37 1 201185818 201185818 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 29 87 0 ENST00000335211.4:c.9532G>A p.Ala3178Thr p.A3178T ENST00000335211 NM_001164586.1 3178 Gct/Act 0 +IGHMBP2 UCSF GRCh37 11 68703919 68703919 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 65 121 0 ENST00000255078.3:c.1971G>A p.Gln657= p.Q657= ENST00000255078 NM_002180.2 657 caG/caA 0 +IGSF23 UCSF GRCh37 19 45127135 45127135 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 53 160 0 ENST00000402988.1:c.257G>A p.Ser86Asn p.S86N ENST00000402988 NM_001205280.1 86 aGt/aAt 0 +IGSF9 UCSF GRCh37 1 159898138 159898138 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 14 38 0 ENST00000368094.1:c.3040C>T p.Pro1014Ser p.P1014S ENST00000368094 NM_001135050.1 1014 Cct/Tct 0 +IK UCSF GRCh37 5 140037151 140037151 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 236 154 353 0 ENST00000417647.2:c.814C>T p.Leu272= p.L272= ENST00000417647 NM_006083.3 272 Ctg/Ttg 0 +IKBKB UCSF GRCh37 8 42174227 42174227 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 33 72 0 ENST00000520810.1:c.931-1G>A p.X311_splice ENST00000520810 NM_001556.2 0 +IKZF1 UCSF GRCh37 7 50444387 50444387 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 164 99 244 0 ENST00000331340.3:c.317G>A p.Gly106Glu p.G106E ENST00000331340 NM_006060.4 106 gGa/gAa 0 +IKZF5 UCSF GRCh37 10 124753424 124753424 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 91 193 0 ENST00000368886.5:c.1132C>T p.Leu378Phe p.L378F ENST00000368886 NM_001271840.1 378 Ctt/Ttt 0 +IL17RC UCSF GRCh37 3 9974706 9974706 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 10 23 0 ENST00000295981.3:c.1805G>A p.Gly602Asp p.G602D ENST00000295981 NM_153461.3 602 gGc/gAc 0 +IL20RB UCSF GRCh37 3 136710806 136710806 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 82 163 0 ENST00000329582.4:c.558G>A p.Gly186= p.G186= ENST00000329582 NM_144717.3 186 ggG/ggA 0 +ILF3 UCSF GRCh37 19 10793267 10793267 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 36 79 0 ENST00000449870.1:c.1435G>A p.Gly479Arg p.G479R ENST00000449870 NM_017620.2 479 Ggg/Agg 0 +IMP5 UCSF GRCh37 17 43924060 43924060 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 73 134 0 ENST00000329196.5:c.1788C>T p.Asp596= p.D596= ENST00000329196 NM_175882.2 596 gaC/gaT 0 +IMPG2 UCSF GRCh37 3 100994553 100994553 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 61 141 0 ENST00000193391.7:c.620C>T p.Ala207Val p.A207V ENST00000193391 NM_016247.3 207 gCc/gTc 0 +IMPG2 UCSF GRCh37 3 100961716 100961716 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 73 167 0 ENST00000193391.7:c.2838C>T p.Phe946= p.F946= ENST00000193391 NM_016247.3 946 ttC/ttT 0 +INADL UCSF GRCh37 1 62240978 62240978 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 168 117 276 0 ENST00000371158.2:c.821C>T p.Thr274Ile p.T274I ENST00000371158 NM_176877.2 274 aCt/aTt 0 +INO80D UCSF GRCh37 2 206921489 206921489 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0021 P18_Rec Untested WXS Illumina HiSeq 112 86 211 0 ENST00000403263.1:c.397C>T p.Pro133Ser p.P133S ENST00000403263 NM_017759.4 133 Cca/Tca 0 +INPP4A UCSF GRCh37 2 99136584 99136584 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 8 57 0 ENST00000074304.5:c.73G>A p.Val25Met p.V25M ENST00000074304 NM_001134224.1 25 Gtg/Atg 0 +INPP4A UCSF GRCh37 2 99170778 99170778 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 48 82 0 ENST00000074304.5:c.1407C>T p.Asn469= p.N469= ENST00000074304 NM_001134224.1 469 aaC/aaT 0 +INPP5F UCSF GRCh37 10 121579000 121579000 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 37 117 0 ENST00000361976.2:c.1887-1358G>A *629* ENST00000361976 NM_014937.3 0 +INPP5K UCSF GRCh37 17 1416790 1416790 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 165 114 231 0 ENST00000421807.2:c.218G>A p.Ser73Asn p.S73N ENST00000421807 NM_016532.3 73 aGc/aAc 0 +INTS10 UCSF GRCh37 8 19675133 19675133 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 7 8 15 0 ENST00000397977.3:c.85C>T p.Leu29= p.L29= ENST00000397977 NM_018142.2 29 Ctg/Ttg 0 +INTS3 UCSF GRCh37 1 153736307 153736307 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 14 42 0 ENST00000318967.2:c.1767-1G>A p.X589_splice ENST00000318967 NM_023015.3 0 +INTS3 UCSF GRCh37 1 153740288 153740288 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 63 109 0 ENST00000318967.2:c.2229C>T p.Pro743= p.P743= ENST00000318967 NM_023015.3 743 ccC/ccT 0 +INTS5 UCSF GRCh37 11 62414821 62414821 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 108 176 0 ENST00000330574.2:c.2731G>A p.Val911Met p.V911M ENST00000330574 NM_030628.1 911 Gtg/Atg 0 +IP6K3 UCSF GRCh37 6 33696027 33696027 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 37 84 0 ENST00000451316.1:c.250G>A p.Val84Ile p.V84I ENST00000451316 NM_001142883.1 84 Gtt/Att 0 +IPO4 UCSF GRCh37 14 24656119 24656119 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 41 111 0 ENST00000354464.6:c.721C>T p.Pro241Ser p.P241S ENST00000354464 NM_024658.3 241 Ccc/Tcc 0 +IPO5 UCSF GRCh37 13 98654779 98654779 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 66 186 0 ENST00000261574.5:c.1221C>T p.Cys407= p.C407= ENST00000261574 NM_002271.4 407 tgC/tgT 0 +IQCB1 UCSF GRCh37 3 121544935 121544935 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 46 122 0 ENST00000310864.6:c.356G>A p.Gly119Glu p.G119E ENST00000310864 NM_001023570.2 119 gGg/gAg 0 +IQCG UCSF GRCh37 3 197619574 197619574 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 165 133 320 0 ENST00000265239.6:c.1020G>A p.Met340Ile p.M340I ENST00000265239 NM_032263.3 340 atG/atA 0 +IQCJ-SCHIP1 UCSF GRCh37 3 159606716 159606716 + synonymous_variant Silent SNP C C T snp132_rs2306063 P18_Rec Untested WXS Illumina HiSeq 121 93 201 0 ENST00000445224.2:c.573C>T p.Leu191= p.L191= ENST00000445224 NM_001197109.1 191 ctC/ctT 0 +IREB2 UCSF GRCh37 15 78786575 78786575 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 224 125 301 0 ENST00000258886.8:c.2564G>A p.Arg855Lys p.R855K ENST00000258886 NM_004136.2 855 aGa/aAa 0 +IRF2 UCSF GRCh37 4 185350210 185350210 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 44 78 0 ENST00000393593.3:c.9G>A p.Val3= p.V3= ENST00000393593 NM_002199.3 3 gtG/gtA 0 +IRF2BP2 UCSF GRCh37 1 234743566 234743566 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 35 87 0 ENST00000366609.3:c.1081C>T p.Pro361Ser p.P361S ENST00000366609 NM_182972.2 361 Cca/Tca 0 +IRS4 UCSF GRCh37 X 107977198 107977198 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 166 159 0 ENST00000372129.2:c.2377C>T p.Pro793Ser p.P793S ENST00000372129 NM_003604.2 793 Ccc/Tcc 0 +IRX1 UCSF GRCh37 5 3600728 3600728 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 52 32 90 0 ENST00000302006.3:c.1318G>A p.Asp440Asn p.D440N ENST00000302006 NM_024337.3 440 Gac/Aac 0 +ITFG1 UCSF GRCh37 16 47409814 47409814 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 45 118 0 ENST00000320640.6:c.693C>T p.Thr231= p.T231= ENST00000320640 NM_030790.3 231 acC/acT 0 +ITGA5 UCSF GRCh37 12 54795811 54795811 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 51 131 0 ENST00000293379.4:c.2200G>A p.Gly734Ser p.G734S ENST00000293379 NM_002205.2 734 Ggc/Agc 0 +ITGA8 UCSF GRCh37 10 15647730 15647730 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 36 89 0 ENST00000378076.3:c.1963G>A p.Ala655Thr p.A655T ENST00000378076 NM_003638.1 655 Gct/Act 0 +ITGA8 UCSF GRCh37 10 15719614 15719614 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 239 126 185 0 ENST00000378076.3:c.653G>A p.Gly218Glu p.G218E ENST00000378076 NM_003638.1 218 gGa/gAa 0 +ITGAD UCSF GRCh37 16 31429662 31429662 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 56 115 0 ENST00000389202.2:c.2657C>T p.Thr886Ile p.T886I ENST00000389202 NM_005353.2 886 aCc/aTc 0 +ITGAL UCSF GRCh37 16 30500707 30500707 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 49 123 1 ENST00000356798.6:c.1213G>A p.Gly405Ser p.G405S ENST00000356798 NM_002209.2 405 Ggt/Agt 0 +ITGB3 UCSF GRCh37 17 45360902 45360902 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 46 121 0 ENST00000559488.1:c.348C>T p.Leu116= p.L116= ENST00000559488 NM_000212.2 116 ctC/ctT 0 +ITGB4 UCSF GRCh37 17 73739880 73739880 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 19 40 0 ENST00000200181.3:c.3049C>T p.Leu1017= p.L1017= ENST00000200181 NM_000213.3 1017 Ctg/Ttg 0 +ITGB4 UCSF GRCh37 17 73752517 73752517 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 41 112 0 ENST00000200181.3:c.4716G>A p.Leu1572= p.L1572= ENST00000200181 NM_000213.3 1572 ctG/ctA 0 +ITIH1 UCSF GRCh37 3 52812466 52812466 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 90 220 0 ENST00000273283.2:c.249G>A p.Arg83= p.R83= ENST00000273283 NM_002215.3 83 agG/agA 0 +ITPKC UCSF GRCh37 19 41224119 41224119 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 55 111 0 ENST00000263370.2:c.1079C>T p.Ala360Val p.A360V ENST00000263370 NM_025194.2 360 gCc/gTc 0 +ITPR1 UCSF GRCh37 3 4715049 4715049 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 580 120 296 0 ENST00000302640.8:c.2389C>T p.Pro797Ser p.P797S ENST00000302640 NM_001168272.1 797 Ccc/Tcc 0 +ITPR1 UCSF GRCh37 3 4722322 4722322 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 292 56 135 0 ENST00000302640.8:c.3008C>T p.Thr1003Ile p.T1003I ENST00000302640 NM_001168272.1 1003 aCt/aTt 0 +ITPR1 UCSF GRCh37 3 4681123 4681123 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 355 76 154 0 ENST00000302640.8:c.335G>A p.Gly112Glu p.G112E ENST00000302640 NM_001168272.1 112 gGg/gAg 0 +ITPR1 UCSF GRCh37 3 4808213 4808213 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 428 88 233 0 ENST00000302640.8:c.5500-1G>A p.X1834_splice ENST00000302640 NM_001168272.1 0 +ITPR1 UCSF GRCh37 3 4829658 4829658 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 551 132 263 0 ENST00000302640.8:c.6598C>T p.Gln2200Ter p.Q2200* ENST00000302640 NM_001168272.1 2200 Cag/Tag 0 +ITPR1 UCSF GRCh37 3 4817088 4817088 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 629 140 305 0 ENST00000302640.8:c.6097C>T p.Leu2033= p.L2033= ENST00000302640 NM_001168272.1 2033 Ctg/Ttg 0 +IWS1 UCSF GRCh37 2 128238734 128238734 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 70 157 0 ENST00000295321.4:c.2346G>A p.Lys782= p.K782= ENST00000295321 NM_017969.2 782 aaG/aaA 0 +JAG1 UCSF GRCh37 20 10620400 10620400 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 53 139 0 ENST00000254958.5:c.3403C>T p.Pro1135Ser p.P1135S ENST00000254958 NM_000214.2 1135 Ccc/Tcc 0 +JAKMIP2 UCSF GRCh37 5 147030033 147030033 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 60 146 0 ENST00000265272.5:c.705G>A p.Gln235= p.Q235= ENST00000265272 NM_014790.4 235 caG/caA 0 +JKAMP UCSF GRCh37 14 59970668 59970668 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 173 135 272 0 ENST00000261247.9:c.814G>A p.Asp272Asn p.D272N ENST00000261247 NM_001098625.1 272 Gat/Aat 0 +JUB UCSF GRCh37 14 23443256 23443256 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 144 103 249 0 ENST00000262713.2:c.1491G>A p.Glu497= p.E497= ENST00000262713 NM_032876.4 497 gaG/gaA 0 +JUNB UCSF GRCh37 19 12902742 12902742 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 28 47 0 ENST00000302754.4:c.157C>T p.Pro53Ser p.P53S ENST00000302754 NM_002229.2 53 Cct/Tct 0 +KANK1 UCSF GRCh37 9 713345 713345 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 108 229 0 ENST00000382303.1:c.2579G>A p.Gly860Asp p.G860D ENST00000382303 NM_001256876.1 860 gGc/gAc 0 +KANK4 UCSF GRCh37 1 62740568 62740568 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 97 194 0 ENST00000371153.4:c.208C>T p.Pro70Ser p.P70S ENST00000371153 NM_181712.4 70 Ccc/Tcc 0 +KAT6B UCSF GRCh37 10 76602646 76602646 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 103 246 0 ENST00000287239.4:c.31G>A p.Glu11Lys p.E11K ENST00000287239 NM_001256468.1 11 Gag/Aag 0 +KAZN UCSF GRCh37 1 15382767 15382767 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 26 57 0 ENST00000376030.2:c.907G>A p.Asp303Asn p.D303N ENST00000376030 NM_201628.2 303 Gac/Aac 0 +KBTBD10 UCSF GRCh37 2 170382119 170382119 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 80 197 0 ENST00000284669.1:c.1734G>A p.Trp578Ter p.W578* ENST00000284669 NM_006063.2 578 tgG/tgA 0 +KBTBD10 UCSF GRCh37 2 170374757 170374757 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 73 149 0 ENST00000284669.1:c.1434G>A p.Leu478= p.L478= ENST00000284669 NM_006063.2 478 ctG/ctA 0 +KBTBD6 UCSF GRCh37 13 41705456 41705456 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 92 239 0 ENST00000379485.1:c.1192G>A p.Ala398Thr p.A398T ENST00000379485 NM_152903.4 398 Gct/Act 0 +KCNA4 UCSF GRCh37 11 30033280 30033280 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 91 203 0 ENST00000328224.6:c.946G>A p.Val316Ile p.V316I ENST00000328224 NM_002233.3 316 Gtc/Atc 0 +KCND2 UCSF GRCh37 7 119914851 119914851 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 117 237 0 ENST00000331113.4:c.165G>A p.Trp55Ter p.W55* ENST00000331113 NM_012281.2 55 tgG/tgA 0 +KCND3 UCSF GRCh37 1 112524839 112524839 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 33 101 0 ENST00000315987.2:c.510G>A p.Trp170Ter p.W170* ENST00000315987 NM_004980.4 170 tgG/tgA 0 +KCNF1 UCSF GRCh37 2 11053062 11053062 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 24 82 0 ENST00000295082.1:c.510G>A p.Lys170= p.K170= ENST00000295082 NM_002236.4 170 aaG/aaA 0 +KCNH1 UCSF GRCh37 1 210857328 210857328 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 38 86 0 ENST00000271751.4:c.2265G>A p.Glu755= p.E755= ENST00000271751 755 gaG/gaA 0 +KCNH6 UCSF GRCh37 17 61607784 61607784 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 59 132 0 ENST00000583023.1:c.556C>T p.Leu186Phe p.L186F ENST00000583023 NM_030779.3 186 Ctc/Ttc 0 +KCNH8 UCSF GRCh37 3 19295191 19295191 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 104 236 0 ENST00000328405.2:c.122C>T p.Pro41Leu p.P41L ENST00000328405 NM_144633.2 41 cCc/cTc 0 +KCNJ16 UCSF GRCh37 17 68129012 68129012 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 182 114 274 0 ENST00000392670.1:c.784C>T p.Pro262Ser p.P262S ENST00000392670 262 Cct/Tct 0 +KCNJ3 UCSF GRCh37 2 155711415 155711415 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 75 196 0 ENST00000295101.2:c.1096C>T p.Leu366Phe p.L366F ENST00000295101 NM_002239.3 366 Ctc/Ttc 0 +KCNK1 UCSF GRCh37 1 233802420 233802420 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 39 100 0 ENST00000366621.3:c.435C>T p.Thr145= p.T145= ENST00000366621 NM_002245.3 145 acC/acT 0 +KCNK13 UCSF GRCh37 14 90650846 90650846 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 90 208 0 ENST00000282146.4:c.726C>T p.Asp242= p.D242= ENST00000282146 NM_022054.3 242 gaC/gaT 0 +KCNK16 UCSF GRCh37 6 39282863 39282863 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 61 142 0 ENST00000425054.2:c.*37G>A *13* ENST00000425054 NM_001135105.1 0 +KCNK17 UCSF GRCh37 6 39267491 39267491 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 76 139 0 ENST00000373231.4:c.711C>T p.Tyr237= p.Y237= ENST00000373231 NM_031460.3 237 taC/taT 0 +KCNK4 UCSF GRCh37 11 64065096 64065096 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 86 57 131 0 ENST00000539216.1:c.632C>T p.Thr211Ile p.T211I ENST00000539216 211 aCc/aTc 0 +KCNK5 UCSF GRCh37 6 39162060 39162060 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 75 145 0 ENST00000359534.3:c.519C>T p.Val173= p.V173= ENST00000359534 NM_003740.3 173 gtC/gtT 0 +KCNMA1 UCSF GRCh37 10 79163778 79163778 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 54 106 0 ENST00000404857.1:c.382G>A p.Ala128Thr p.A128T ENST00000404857 NM_001161353.1 128 Gcc/Acc 0 +KCNT1 UCSF GRCh37 9 138645788 138645788 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 27 64 1 ENST00000371757.2:c.440G>A p.Gly147Asp p.G147D ENST00000371757 NM_020822.2 147 gGc/gAc 0 +KCNT1 UCSF GRCh37 9 138649046 138649046 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 44 119 0 ENST00000371757.2:c.645G>A p.Glu215= p.E215= ENST00000371757 NM_020822.2 215 gaG/gaA 0 +KCNT1 UCSF GRCh37 9 138678090 138678090 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 9 18 0 ENST00000371757.2:c.3225G>A p.Val1075= p.V1075= ENST00000371757 NM_020822.2 1075 gtG/gtA 0 +KCNU1 UCSF GRCh37 8 36691074 36691074 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 229 201 371 0 ENST00000399881.3:c.1109C>T p.Thr370Ile p.T370I ENST00000399881 NM_001031836.2 370 aCc/aTc 0 +KDM2B UCSF GRCh37 12 122016746 122016746 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 42 68 0 ENST00000377071.4:c.232C>T p.Leu78= p.L78= ENST00000377071 NM_032590.4 78 Ctg/Ttg 0 +KDM3B UCSF GRCh37 5 137754882 137754882 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 54 131 0 ENST00000314358.5:c.3676G>A p.Ala1226Thr p.A1226T ENST00000314358 NM_016604.3 1226 Gca/Aca 0 +KDM3B UCSF GRCh37 5 137767249 137767249 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 74 212 0 ENST00000314358.5:c.5205+1G>A p.X1735_splice ENST00000314358 NM_016604.3 0 +KERA UCSF GRCh37 12 91445287 91445287 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 52 134 0 ENST00000266719.3:c.895G>A p.Val299Ile p.V299I ENST00000266719 NM_007035.3 299 Gtc/Atc 0 +KIAA0100 UCSF GRCh37 17 26945953 26945953 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 57 105 0 ENST00000528896.2:c.5679G>A p.Lys1893= p.K1893= ENST00000528896 NM_014680.3 1893 aaG/aaA 0 +KIAA0100 UCSF GRCh37 17 26950785 26950785 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 83 171 0 ENST00000528896.2:c.4952G>A p.Trp1651Ter p.W1651* ENST00000528896 NM_014680.3 1651 tGg/tAg 0 +KIAA0100 UCSF GRCh37 17 26960944 26960944 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 65 137 0 ENST00000528896.2:c.3231G>A p.Met1077Ile p.M1077I ENST00000528896 NM_014680.3 1077 atG/atA 0 +KIAA0141 UCSF GRCh37 5 141305047 141305047 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 67 162 0 ENST00000432126.2:c.219G>A p.Met73Ile p.M73I ENST00000432126 NM_014773.3 73 atG/atA 0 +KIAA0196 UCSF GRCh37 8 126093945 126093945 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 119 60 185 0 ENST00000318410.7:c.476G>A p.Gly159Glu p.G159E ENST00000318410 NM_014846.3 159 gGa/gAa 0 +KIAA0226 UCSF GRCh37 3 197421334 197421334 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 77 177 0 ENST00000296343.5:c.1596C>T p.Ile532= p.I532= ENST00000296343 NM_014687.1 532 atC/atT 0 +KIAA0232 UCSF GRCh37 4 6863304 6863304 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 89 163 0 ENST00000307659.5:c.1195G>A p.Glu399Lys p.E399K ENST00000307659 NM_014743.2 399 Gag/Aag 0 +KIAA0240 UCSF GRCh37 6 42797076 42797076 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 188 157 330 0 ENST00000314073.5:c.1005G>A p.Gln335= p.Q335= ENST00000314073 335 caG/caA 0 +KIAA0284 UCSF GRCh37 14 105350247 105350247 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 17 52 0 ENST00000414716.3:c.1131G>A p.Leu377= p.L377= ENST00000414716 NM_001112726.2 377 ttG/ttA 0 +KIAA0415 UCSF GRCh37 7 4821359 4821359 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 28 78 0 ENST00000348624.4:c.340C>T p.Leu114= p.L114= ENST00000348624 NM_014855.2 114 Ctg/Ttg 0 +KIAA0430 UCSF GRCh37 16 15710946 15710946 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 205 77 188 0 ENST00000396368.3:c.3040C>T p.Leu1014Phe p.L1014F ENST00000396368 NM_001184998.1 1014 Ctt/Ttt 0 +KIAA0564 UCSF GRCh37 13 42295652 42295652 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 95 156 0 ENST00000379310.3:c.2818C>T p.Leu940Phe p.L940F ENST00000379310 NM_015058.1 940 Ctc/Ttc 0 +KIAA0889 UCSF GRCh37 20 35444374 35444374 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 27 70 0 ENST00000237536.4:c.1471C>T p.Pro491Ser p.P491S ENST00000237536 NM_080627.2 491 Cct/Tct 0 +KIAA0922 UCSF GRCh37 4 154512332 154512332 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 109 267 0 ENST00000409959.3:c.1798C>T p.Leu600Phe p.L600F ENST00000409959 NM_001131007.1 600 Ctt/Ttt 0 +KIAA0947 UCSF GRCh37 5 5464975 5464975 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 40 69 0 ENST00000296564.7:c.5528G>A p.Arg1843Lys p.R1843K ENST00000296564 NM_015325.2 1843 aGa/aAa 0 +KIAA1211 UCSF GRCh37 4 57190331 57190331 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 36 120 0 ENST00000504228.1:c.3440C>T p.Ser1147Phe p.S1147F ENST00000504228 1147 tCc/tTc 0 +KIAA1211 UCSF GRCh37 4 57182328 57182328 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 20 73 0 ENST00000504228.1:c.2660G>A p.Gly887Glu p.G887E ENST00000504228 887 gGg/gAg 0 +KIAA1217 UCSF GRCh37 10 24813287 24813287 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 101 63 110 0 ENST00000376454.3:c.2492C>T p.Ala831Val p.A831V ENST00000376454 NM_019590.3 831 gCa/gTa 0 +KIAA1217 UCSF GRCh37 10 24813626 24813626 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 141 41 98 0 ENST00000376454.3:c.2831C>T p.Ala944Val p.A944V ENST00000376454 NM_019590.3 944 gCc/gTc 0 +KIAA1217 UCSF GRCh37 10 24831845 24831845 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 59 104 0 ENST00000376454.3:c.3646C>T p.Pro1216Ser p.P1216S ENST00000376454 NM_019590.3 1216 Cct/Tct 0 +KIAA1217 UCSF GRCh37 10 24834887 24834887 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 279 149 263 0 ENST00000376454.3:c.5466C>T p.Ser1822= p.S1822= ENST00000376454 NM_019590.3 1822 agC/agT 0 +KIAA1310 UCSF GRCh37 2 97267863 97267863 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 26 57 0 ENST00000431828.1:c.2472C>T p.Asn824= p.N824= ENST00000431828 824 aaC/aaT 0 +KIAA1370 UCSF GRCh37 15 52903407 52903407 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 132 341 0 ENST00000261844.7:c.450C>T p.Val150= p.V150= ENST00000261844 NM_019600.2 150 gtC/gtT 0 +KIAA1383 UCSF GRCh37 1 232942673 232942673 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 149 126 213 0 ENST00000418460.1:c.1904G>A p.Gly635Glu p.G635E ENST00000418460 NM_019090.2 635 gGg/gAg 0 +KIAA1468 UCSF GRCh37 18 59942649 59942649 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 34 81 0 ENST00000398130.2:c.2910G>A p.Trp970Ter p.W970* ENST00000398130 NM_020854.3 970 tgG/tgA 0 +KIAA1614 UCSF GRCh37 1 180885292 180885292 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 18 52 0 ENST00000367588.4:c.53G>A p.Gly18Glu p.G18E ENST00000367588 NM_020950.1 18 gGg/gAg 0 +KIAA1671 UCSF GRCh37 22 25424711 25424711 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 5 17 28 0 ENST00000358431.3:c.745G>A p.Glu249Lys p.E249K ENST00000358431 NM_001145206.1 249 Gag/Aag 0 +KIAA1958 UCSF GRCh37 9 115408050 115408050 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 81 182 0 ENST00000337530.6:c.1292G>A p.Trp431Ter p.W431* ENST00000337530 NM_001287038.1 431 tGg/tAg 0 +KIAA2018 UCSF GRCh37 3 113377351 113377351 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 167 107 268 0 ENST00000316407.4:c.3178G>A p.Asp1060Asn p.D1060N ENST00000316407 NM_001009899.2 1060 Gat/Aat 0 +KIAA2018 UCSF GRCh37 3 113380149 113380149 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 143 96 227 0 ENST00000316407.4:c.380G>A p.Gly127Glu p.G127E ENST00000316407 NM_001009899.2 127 gGa/gAa 0 +KIF12 UCSF GRCh37 9 116854152 116854152 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 41 0 ENST00000374118.3:c.1531C>T p.Pro511Ser p.P511S ENST00000374118 NM_138424.1 511 Cct/Tct 0 +KIF13A UCSF GRCh37 6 17817358 17817358 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 70 105 0 ENST00000259711.6:c.1893C>T p.Leu631= p.L631= ENST00000259711 NM_022113.5 631 ctC/ctT 0 +KIF13A UCSF GRCh37 6 17799560 17799560 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 69 137 0 ENST00000259711.6:c.2727C>T p.Asp909= p.D909= ENST00000259711 NM_022113.5 909 gaC/gaT 0 +KIF15 UCSF GRCh37 3 44868999 44868999 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 43 119 0 ENST00000326047.4:c.2835G>A p.Glu945= p.E945= ENST00000326047 NM_020242.2 945 gaG/gaA 0 +KIF19 UCSF GRCh37 17 72351387 72351387 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 39 29 77 0 ENST00000389916.4:c.2933G>A p.Arg978His p.R978H ENST00000389916 NM_153209.3 978 cGt/cAt 0 +KIF1B UCSF GRCh37 1 10386370 10386370 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 71 151 0 ENST00000263934.6:c.2739G>A p.Gly913= p.G913= ENST00000263934 NM_015074.3 913 ggG/ggA 0 +KIF1B UCSF GRCh37 1 10402188 10402188 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 187 133 312 0 ENST00000263934.6:c.3456G>A p.Gln1152= p.Q1152= ENST00000263934 NM_015074.3 1152 caG/caA 0 +KIF21B UCSF GRCh37 1 200959124 200959124 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 32 91 0 ENST00000422435.2:c.3078C>T p.Ser1026= p.S1026= ENST00000422435 NM_001252100.1 1026 tcC/tcT 0 +KIF26A UCSF GRCh37 14 104639339 104639339 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 30 19 51 0 ENST00000423312.2:c.1446G>A p.Lys482= p.K482= ENST00000423312 NM_015656.1 482 aaG/aaA 0 +KIF3B UCSF GRCh37 20 30919053 30919053 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 69 166 0 ENST00000375712.3:c.2175C>T p.Ser725= p.S725= ENST00000375712 NM_004798.3 725 tcC/tcT 0 +KIF5B UCSF GRCh37 10 32321645 32321645 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 79 182 0 ENST00000302418.4:c.1363G>A p.Asp455Asn p.D455N ENST00000302418 NM_004521.2 455 Gat/Aat 0 +KIF5B UCSF GRCh37 10 32311839 32311839 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 87 192 0 ENST00000302418.4:c.1851G>A p.Glu617= p.E617= ENST00000302418 NM_004521.2 617 gaG/gaA 0 +KIFC3 UCSF GRCh37 16 57793698 57793698 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 7 19 0 ENST00000379655.4:c.2418C>T p.Ala806= p.A806= ENST00000379655 NM_005550.3 806 gcC/gcT 0 +KIRREL3 UCSF GRCh37 11 126333116 126333116 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 32 70 0 ENST00000525144.2:c.678G>A p.Val226= p.V226= ENST00000525144 NM_032531.3 226 gtG/gtA 0 +KLF17 UCSF GRCh37 1 44595450 44595450 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 48 133 0 ENST00000372299.3:c.507G>A p.Met169Ile p.M169I ENST00000372299 NM_173484.3 169 atG/atA 0 +KLF6 UCSF GRCh37 10 3824180 3824180 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 245 159 227 0 ENST00000497571.1:c.329G>A p.Ser110Asn p.S110N ENST00000497571 NM_001300.5 110 aGc/aAc 0 +KLHDC10 UCSF GRCh37 7 129762040 129762040 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 186 215 0 ENST00000335420.5:c.777G>A p.Glu259= p.E259= ENST00000335420 NM_014997.3 259 gaG/gaA 0 +KLHDC8B UCSF GRCh37 3 49211804 49211804 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 56 157 0 ENST00000332780.2:c.509C>T p.Thr170Ile p.T170I ENST00000332780 NM_173546.2 170 aCc/aTc 0 +KLHL17 UCSF GRCh37 1 899356 899356 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 80 134 0 ENST00000338591.3:c.1412C>T p.Thr471Ile p.T471I ENST00000338591 NM_198317.2 471 aCc/aTc 0 +KLHL17 UCSF GRCh37 1 898853 898853 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 25 54 0 ENST00000338591.3:c.1324G>A p.Gly442Ser p.G442S ENST00000338591 NM_198317.2 442 Ggc/Agc 0 +KLHL17 UCSF GRCh37 1 897130 897130 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 15 63 0 ENST00000338591.3:c.489G>A p.Gln163= p.Q163= ENST00000338591 NM_198317.2 163 caG/caA 0 +KLHL21 UCSF GRCh37 1 6653605 6653605 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 44 31 85 0 ENST00000377658.4:c.1614C>T p.Arg538= p.R538= ENST00000377658 NM_014851.2 538 cgC/cgT 0 +KLHL7 UCSF GRCh37 7 23205492 23205492 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 66 156 0 ENST00000339077.5:c.1112C>A p.Pro371His p.P371H ENST00000339077 NM_001031710.2 371 cCt/cAt 0 +KLHL8 UCSF GRCh37 4 88106529 88106529 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 163 135 256 0 ENST00000273963.5:c.639C>T p.Leu213= p.L213= ENST00000273963 NM_020803.3 213 ctC/ctT 0 +KLK10 UCSF GRCh37 19 51519265 51519265 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 6 11 0 ENST00000309958.3:c.417G>A p.Met139Ile p.M139I ENST00000309958 NM_002776.4 139 atG/atA 0 +KLK12 UCSF GRCh37 19 51534051 51534051 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 68 139 0 ENST00000250351.4:c.584C>T p.Ala195Val p.A195V ENST00000250351 195 gCc/gTc 0 +KPNA3 UCSF GRCh37 13 50306749 50306749 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 68 190 0 ENST00000261667.3:c.279G>A p.Gln93= p.Q93= ENST00000261667 NM_002267.3 93 caG/caA 0 +KPRP UCSF GRCh37 1 152733154 152733154 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 44 96 0 ENST00000368773.1:c.1090G>A p.Gly364Ser p.G364S ENST00000368773 NM_001025231.1 364 Ggc/Agc 0 +KREMEN1 UCSF GRCh37 22 29490366 29490366 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 68 8 141 0 ENST00000327813.5:c.218A>C p.Tyr73Ser p.Y73S ENST00000327813 NM_032045.4 73 tAc/tCc 0 +KRT12 UCSF GRCh37 17 39019559 39019559 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 30 26 64 0 ENST00000251643.4:c.1132G>A p.Gly378Ser p.G378S ENST00000251643 NM_000223.3 378 Ggc/Agc 0 +KRT17 UCSF GRCh37 17 39777949 39777949 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 98 171 0 ENST00000311208.8:c.730G>A p.Ala244Thr p.A244T ENST00000311208 NM_000422.2 244 Gcc/Acc 0 +KRT23 UCSF GRCh37 17 39081672 39081672 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 60 154 0 ENST00000209718.3:c.1076G>A p.Gly359Asp p.G359D ENST00000209718 NM_015515.3 359 gGc/gAc 0 +KRTAP10-3 UCSF GRCh37 21 45977945 45977945 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.005,1000g2011may_all_0.0170,snp132_rs13047815 P18_Rec Untested WXS Illumina HiSeq 42 29 66 0 ENST00000391620.1:c.654G>A p.Lys218= p.K218= ENST00000391620 NM_198696.2 218 aaG/aaA 0 +KRTAP4-7 UCSF GRCh37 17 39240848 39240848 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 49 96 0 ENST00000391417.4:c.390C>T p.Cys130= p.C130= ENST00000391417 NM_033061.3 130 tgC/tgT 0 +KRTCAP3 UCSF GRCh37 2 27666821 27666821 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 56 96 0 ENST00000543753.1:c.621G>A p.Glu207= p.E207= ENST00000543753 NM_001168364.1 207 gaG/gaA 0 +KSR2 UCSF GRCh37 12 118199019 118199019 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 56 91 0 ENST00000339824.5:c.783G>A p.Pro261= p.P261= ENST00000339824 261 ccG/ccA 0 +KTI12 UCSF GRCh37 1 52498937 52498937 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 59 151 0 ENST00000371614.1:c.497C>T p.Ala166Val p.A166V ENST00000371614 NM_138417.2 166 gCc/gTc 0 +LAG3 UCSF GRCh37 12 6882393 6882393 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 62 104 0 ENST00000203629.2:c.94G>A p.Val32Met p.V32M ENST00000203629 NM_002286.5 32 Gtg/Atg 0 +LAIR2 UCSF GRCh37 19 55021774 55021774 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 76 220 0 ENST00000301202.2:c.454C>T p.Pro152Ser p.P152S ENST00000301202 NM_002288.4 152 Cca/Tca 0 +LAMA3 UCSF GRCh37 18 21529802 21529802 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 56 145 0 ENST00000313654.9:c.9425C>T p.Ser3142Phe p.S3142F ENST00000313654 NM_198129.1 3142 tCt/tTt 0 +LAMA5 UCSF GRCh37 20 60909396 60909396 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 17 0 ENST00000252999.3:c.2585C>T p.Pro862Leu p.P862L ENST00000252999 NM_005560.4 862 cCt/cTt 0 +LAMB1 UCSF GRCh37 7 107599749 107599749 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 131 92 212 0 ENST00000222399.6:c.2635G>A p.Val879Met p.V879M ENST00000222399 NM_002291.2 879 Gtg/Atg 0 +LAMB4 UCSF GRCh37 7 107696233 107696233 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 53 131 0 ENST00000388781.3:c.3599C>T p.Ala1200Val p.A1200V ENST00000388781 NM_007356.2 1200 gCt/gTt 0 +LAMB4 UCSF GRCh37 7 107708557 107708557 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 93 164 0 ENST00000388781.3:c.2350C>T p.Leu784Phe p.L784F ENST00000388781 NM_007356.2 784 Ctt/Ttt 0 +LAMTOR2 UCSF GRCh37 1 156025217 156025217 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 59 121 0 ENST00000368305.4:c.231+1G>A p.X77_splice ENST00000368305 NM_014017.3 0 +LANCL2 UCSF GRCh37 7 55467677 55467677 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 120 264 0 ENST00000254770.2:c.558C>T p.Val186= p.V186= ENST00000254770 NM_018697.3 186 gtC/gtT 0 +LARS2 UCSF GRCh37 3 45518014 45518014 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 75 187 0 ENST00000415258.1:c.913G>A p.Ala305Thr p.A305T ENST00000415258 305 Gcc/Acc 0 +LARS2 UCSF GRCh37 3 45561725 45561725 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 110 80 174 0 ENST00000415258.1:c.2229C>T p.Phe743= p.F743= ENST00000415258 743 ttC/ttT 0 +LBP UCSF GRCh37 20 37005267 37005267 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 171 114 271 0 ENST00000217407.2:c.1402G>A p.Asp468Asn p.D468N ENST00000217407 NM_004139.3 468 Gac/Aac 0 +LCA5 UCSF GRCh37 6 80198823 80198823 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 105 208 0 ENST00000392959.1:c.1209G>A p.Gln403= p.Q403= ENST00000392959 NM_181714.3 403 caG/caA 0 +LCE1B UCSF GRCh37 1 152785227 152785227 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 45 118 0 ENST00000360090.3:c.305G>A p.Gly102Asp p.G102D ENST00000360090 NM_178349.1 102 gGc/gAc 0 +LCORL UCSF GRCh37 4 17847453 17847453 + downstream_gene_variant 3'Flank SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 154 114 230 0 ENST00000251496 NM_022346.4 0 +LCT UCSF GRCh37 2 136594109 136594109 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 140 83 215 0 ENST00000264162.2:c.631G>T p.Ala211Ser p.A211S ENST00000264162 NM_002299.2 211 Gct/Tct 0 +LETM1 UCSF GRCh37 4 1823919 1823919 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 58 112 0 ENST00000302787.2:c.1597G>A p.Glu533Lys p.E533K ENST00000302787 NM_012318.2 533 Gag/Aag 0 +LGALS4 UCSF GRCh37 19 39297145 39297145 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 68 139 0 ENST00000307751.4:c.430C>T p.Leu144Phe p.L144F ENST00000307751 NM_006149.3 144 Ctt/Ttt 0 +LGALS9C UCSF GRCh37 17 18392297 18392297 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 22 81 0 ENST00000328114.6:c.487C>T p.Pro163Ser p.P163S ENST00000328114 NM_001040078.2 163 Ccg/Tcg 0 +LILRA6 UCSF GRCh37 19 54744315 54744315 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 246 75 304 0 ENST00000396365.2:c.1093C>T p.Pro365Ser p.P365S ENST00000396365 NM_024318.2 365 Cca/Tca 0 +LILRB1 UCSF GRCh37 19 55148046 55148046 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 54 150 0 ENST00000324602.7:c.1755G>A p.Gly585= p.G585= ENST00000324602 NM_001278399.1 585 ggG/ggA 0 +LILRB5 UCSF GRCh37 19 54756405 54756405 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 37 89 0 ENST00000449561.2:c.1482C>T p.Phe494= p.F494= ENST00000449561 494 ttC/ttT 0 +LIMCH1 UCSF GRCh37 4 41652573 41652573 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 53 116 0 ENST00000313860.7:c.1829G>A p.Gly610Asp p.G610D ENST00000313860 NM_014988.2 610 gGt/gAt 0 +LIMK1 UCSF GRCh37 7 73520545 73520545 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 50 154 0 ENST00000336180.2:c.853G>A p.Gly285Ser p.G285S ENST00000336180 NM_002314.3 285 Ggc/Agc 0 +LINGO3 UCSF GRCh37 19 2291415 2291415 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 23 74 0 ENST00000585527.1:c.361G>A p.Val121Ile p.V121I ENST00000585527 121 Gtc/Atc 0 +LIPH UCSF GRCh37 3 185252808 185252808 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 193 134 333 0 ENST00000296252.4:c.162A>G p.Ala54= p.A54= ENST00000296252 NM_139248.2 54 gcA/gcG 0 +LMCD1 UCSF GRCh37 3 8607163 8607163 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 233 64 145 0 ENST00000157600.3:c.769G>A p.Val257Ile p.V257I ENST00000157600 NM_014583.3 257 Gtc/Atc 0 +LMNA UCSF GRCh37 1 156105024 156105024 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 25 68 0 ENST00000368300.4:c.857G>A p.Gly286Glu p.G286E ENST00000368300 NM_170707.3 286 gGg/gAg 0 +LMO7 UCSF GRCh37 13 76379635 76379635 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 156 104 262 0 ENST00000465261.2:c.236G>A p.Gly79Asp p.G79D ENST00000465261 NM_015842.2 79 gGc/gAc 0 +LMO7 UCSF GRCh37 13 76407286 76407286 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 187 162 374 0 ENST00000465261.2:c.2350G>A p.Ala784Thr p.A784T ENST00000465261 NM_015842.2 784 Gca/Aca 0 +LMOD3 UCSF GRCh37 3 69168785 69168785 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 198 154 353 0 ENST00000420581.2:c.721C>T p.Leu241= p.L241= ENST00000420581 NM_198271.3 241 Ctg/Ttg 0 +LMTK2 UCSF GRCh37 7 97770709 97770709 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 86 193 0 ENST00000297293.5:c.232G>A p.Glu78Lys p.E78K ENST00000297293 NM_014916.3 78 Gaa/Aaa 0 +LMTK3 UCSF GRCh37 19 49001311 49001311 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 85 174 0 ENST00000270238.3:c.3102G>A p.Glu1034= p.E1034= ENST00000270238 NM_001080434.1 1034 gaG/gaA 0 +LNPEP UCSF GRCh37 5 96362436 96362436 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 99 175 0 ENST00000231368.5:c.2839G>A p.Glu947Lys p.E947K ENST00000231368 NM_005575.2 947 Gag/Aag 0 +LONP1 UCSF GRCh37 19 5711911 5711911 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 53 88 0 ENST00000360614.3:c.741G>A p.Glu247= p.E247= ENST00000360614 NM_004793.3 247 gaG/gaA 0 +LPA UCSF GRCh37 6 161022079 161022079 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 65 195 0 ENST00000447678.1:c.2997G>A p.Trp999Ter p.W999* ENST00000447678 NM_005577.2 999 tgG/tgA 0 +LPHN2 UCSF GRCh37 1 82436047 82436047 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 125 85 220 0 ENST00000319517.6:c.2732C>T p.Ala911Val p.A911V ENST00000319517 NM_012302.2 911 gCt/gTt 0 +LPHN3 UCSF GRCh37 4 62598985 62598985 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 195 136 317 0 ENST00000514591.1:c.908C>T p.Thr303Ile p.T303I ENST00000514591 303 aCt/aTt 0 +LPO UCSF GRCh37 17 56345285 56345285 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 44 155 0 ENST00000262290.4:c.2069C>T p.Pro690Leu p.P690L ENST00000262290 NM_006151.2 690 cCc/cTc 0 +LRCH1 UCSF GRCh37 13 47262035 47262035 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 48 157 0 ENST00000389797.3:c.871G>A p.Ala291Thr p.A291T ENST00000389797 NM_001164211.1 291 Gca/Aca 0 +LRFN4 UCSF GRCh37 11 66625310 66625310 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 19 59 0 ENST00000309602.4:c.95C>T p.Thr32Ile p.T32I ENST00000309602 NM_024036.4 32 aCc/aTc 0 +LRG1 UCSF GRCh37 19 4538924 4538924 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 38 101 0 ENST00000306390.6:c.72C>T p.Phe24= p.F24= ENST00000306390 NM_052972.2 24 ttC/ttT 0 +LRGUK UCSF GRCh37 7 133848209 133848209 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 87 166 0 ENST00000285928.2:c.856G>A p.Asp286Asn p.D286N ENST00000285928 NM_144648.1 286 Gat/Aat 0 +LRIT1 UCSF GRCh37 10 85994012 85994012 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 80 173 0 ENST00000372105.3:c.712C>T p.Leu238= p.L238= ENST00000372105 NM_015613.2 238 Ctg/Ttg 0 +LRRC15 UCSF GRCh37 3 194081183 194081183 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 155 122 248 0 ENST00000439944.2:c.608G>A p.Gly203Asp p.G203D ENST00000439944 NM_001135057.2 203 gGc/gAc 0 +LRRC16B UCSF GRCh37 14 24534907 24534907 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 62 114 0 ENST00000342740.5:c.3473C>T p.Ala1158Val p.A1158V ENST00000342740 NM_138360.3 1158 gCc/gTc 0 +LRRC17 UCSF GRCh37 7 102584853 102584853 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 134 101 212 0 ENST00000339431.4:c.1125C>T p.Gly375= p.G375= ENST00000339431 NM_001031692.2 375 ggC/ggT 0 +LRRC25 UCSF GRCh37 19 18507245 18507245 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 21 84 0 ENST00000339007.3:c.529C>T p.Leu177Phe p.L177F ENST00000339007 NM_145256.2 177 Ctt/Ttt 0 +LRRC36 UCSF GRCh37 16 67400959 67400959 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 93 194 0 ENST00000329956.6:c.794C>T p.Ser265Phe p.S265F ENST00000329956 NM_018296.5 265 tCc/tTc 0 +LRRC37B UCSF GRCh37 17 30376161 30376161 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 176 126 374 0 ENST00000341671.7:c.2424C>T p.Ser808= p.S808= ENST00000341671 NM_052888.2 808 tcC/tcT 0 +LRRC43 UCSF GRCh37 12 122684865 122684865 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 47 104 0 ENST00000339777.4:c.1479C>T p.Ile493= p.I493= ENST00000339777 NM_152759.4 493 atC/atT 0 +LRRC46 UCSF GRCh37 17 45913823 45913823 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 45 75 0 ENST00000269025.4:c.577C>T p.Pro193Ser p.P193S ENST00000269025 NM_033413.3 193 Cca/Tca 0 +LRRC46 UCSF GRCh37 17 45914311 45914311 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 82 169 0 ENST00000269025.4:c.791C>T p.Ala264Val p.A264V ENST00000269025 NM_033413.3 264 gCc/gTc 0 +LRRC47 UCSF GRCh37 1 3712429 3712429 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 14 12 0 ENST00000378251.1:c.612C>T p.Leu204= p.L204= ENST00000378251 NM_020710.2 204 ctC/ctT 0 +LRRC4B UCSF GRCh37 19 51022257 51022257 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 30 23 49 0 ENST00000599957.1:c.713G>A p.Gly238Asp p.G238D ENST00000599957 238 gGc/gAc 0 +LRRC56 UCSF GRCh37 11 550220 550220 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 2 23 39 0 ENST00000270115.7:c.572C>T p.Thr191Ile p.T191I ENST00000270115 NM_198075.3 191 aCc/aTc 0 +LRRC56 UCSF GRCh37 11 551933 551933 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 2 23 51 0 ENST00000270115.7:c.1004C>T p.Thr335Ile p.T335I ENST00000270115 NM_198075.3 335 aCc/aTc 0 +LRRC61 UCSF GRCh37 7 150034028 150034028 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 45 98 0 ENST00000359623.4:c.78C>T p.Gly26= p.G26= ENST00000359623 NM_001142928.1 26 ggC/ggT 0 +LRRC7 UCSF GRCh37 1 70257745 70257745 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 166 85 229 0 ENST00000035383.5:c.209C>T p.Ala70Val p.A70V ENST00000035383 NM_020794.2 70 gCt/gTt 0 +LRRFIP1 UCSF GRCh37 2 238628200 238628200 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 58 125 0 ENST00000392000.4:c.188G>A p.Arg63Lys p.R63K ENST00000392000 NM_001137552.1 63 aGa/aAa 0 +LRRK2 UCSF GRCh37 12 40728953 40728953 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 72 98 0 ENST00000298910.7:c.5942G>A p.Gly1981Asp p.G1981D ENST00000298910 NM_198578.3 1981 gGt/gAt 0 +LRRK2 UCSF GRCh37 12 40734120 40734120 + synonymous_variant Silent SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 43 143 243 0 ENST00000298910.7:c.5973A>C p.Ile1991= p.I1991= ENST00000298910 NM_198578.3 1991 atA/atC 0 +LRRN2 UCSF GRCh37 1 204588972 204588972 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 26 57 0 ENST00000367175.1:c.149C>T p.Ala50Val p.A50V ENST00000367175 50 gCt/gTt 0 +LRRTM2 UCSF GRCh37 5 138208784 138208784 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 217 186 317 0 ENST00000274711.6:c.1466C>T p.Pro489Leu p.P489L ENST00000274711 NM_015564.2 489 cCc/cTc 0 +LRTM2 UCSF GRCh37 12 1943854 1943854 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 24 63 0 ENST00000543818.1:c.1080C>T p.His360= p.H360= ENST00000543818 NM_001163926.1 360 caC/caT 0 +LRWD1 UCSF GRCh37 7 102106690 102106690 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 60 118 0 ENST00000292616.5:c.405G>A p.Glu135= p.E135= ENST00000292616 NM_152892.1 135 gaG/gaA 0 +LSAMP UCSF GRCh37 3 115560705 115560705 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 76 158 0 ENST00000490035.2:c.906C>T p.Ser302= p.S302= ENST00000490035 NM_002338.3 302 agC/agT 0 +LSM14B UCSF GRCh37 20 60699695 60699695 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 131 102 254 0 ENST00000279068.6:c.150C>T p.Asp50= p.D50= ENST00000279068 NM_144703.2 50 gaC/gaT 0 +LTB4R2 UCSF GRCh37 14 24780661 24780661 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 30 82 0 ENST00000528054.1:c.884G>A p.Gly295Glu p.G295E ENST00000528054 295 gGa/gAa 0 +LTBP4 UCSF GRCh37 19 41128531 41128531 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 18 21 31 0 ENST00000308370.7:c.3641G>A p.Gly1214Asp p.G1214D ENST00000308370 NM_001042544.1 1214 gGc/gAc 0 +LTK UCSF GRCh37 15 41796765 41796765 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 71 159 0 ENST00000263800.6:c.2194G>A p.Val732Met p.V732M ENST00000263800 NM_002344.5 732 Gtg/Atg 0 +LTN1 UCSF GRCh37 21 30329198 30329198 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 52 133 0 ENST00000389194.2:c.3103C>T p.Gln1035Ter p.Q1035* ENST00000389194 NM_015565.2 1035 Cag/Tag 0 +LTN1 UCSF GRCh37 21 30365211 30365211 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 30 30 81 0 ENST00000389194.2:c.54C>T p.Ser18= p.S18= ENST00000389194 NM_015565.2 18 tcC/tcT 0 +LYZL2 UCSF GRCh37 10 30918612 30918612 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 190 35 165 0 ENST00000375318.2:c.23G>A p.Cys8Tyr p.C8Y ENST00000375318 NM_183058.2 8 tGc/tAc 0 +MAGEA10-MAGEA5 UCSF GRCh37 X 151283771 151283771 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 99 96 0 ENST00000427663.2:n.447G>A *149* ENST00000427663 0 +MAGEA8 UCSF GRCh37 X 149013490 149013490 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 113 113 0 ENST00000535454.1:c.444C>T p.Asn148= p.N148= ENST00000535454 NM_001166400.1 148 aaC/aaT 0 +MAGEB1 UCSF GRCh37 X 30269223 30269223 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 3 38 56 0 ENST00000378981.3:c.613C>T p.Leu205= p.L205= ENST00000378981 NM_002363.4 205 Ctg/Ttg 0 +MAGEB16 UCSF GRCh37 X 35820630 35820630 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 66 68 0 ENST00000399989.1:c.317G>A p.Arg106Lys p.R106K ENST00000399989 NM_001099921.1 106 aGg/aAg 0 +MAGI3 UCSF GRCh37 1 114189228 114189228 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 126 106 162 0 ENST00000307546.9:c.2119G>A p.Val707Ile p.V707I ENST00000307546 NM_001142782.1 707 Gtc/Atc 0 +MAGI3 UCSF GRCh37 1 114196583 114196583 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 171 116 310 0 ENST00000307546.9:c.2572G>A p.Glu858Lys p.E858K ENST00000307546 NM_001142782.1 858 Gaa/Aaa 0 +MAGI3 UCSF GRCh37 1 114226361 114226361 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 106 199 0 ENST00000307546.9:c.4171G>A p.Gly1391Arg p.G1391R ENST00000307546 NM_001142782.1 1391 Gga/Aga 0 +MAL2 UCSF GRCh37 8 120252508 120252508 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 161 120 221 0 ENST00000276681.6:c.407C>T p.Thr136Ile p.T136I ENST00000276681 NM_052886.2 136 aCc/aTc 0 +MAMDC2 UCSF GRCh37 9 72840741 72840741 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 40 92 0 ENST00000377182.4:c.1987C>T p.Pro663Ser p.P663S ENST00000377182 NM_153267.4 663 Ccc/Tcc 0 +MANBA UCSF GRCh37 4 103571823 103571823 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 92 188 0 ENST00000226578.4:c.1740G>A p.Lys580= p.K580= ENST00000226578 NM_005908.3 580 aaG/aaA 0 +MANEA UCSF GRCh37 6 96034533 96034533 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 91 176 0 ENST00000358812.4:c.218C>T p.Thr73Ile p.T73I ENST00000358812 NM_024641.3 73 aCc/aTc 0 +MAP1B UCSF GRCh37 5 71491723 71491723 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 140 284 0 ENST00000296755.7:c.2541G>A p.Glu847= p.E847= ENST00000296755 NM_005909.3 847 gaG/gaA 0 +MAP2K4 UCSF GRCh37 17 12016621 12016621 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 108 84 203 0 ENST00000353533.5:c.757C>T p.Gln253Ter p.Q253* ENST00000353533 NM_003010.3 253 Cag/Tag 0 +MAP3K1 UCSF GRCh37 5 56174819 56174819 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 86 186 0 ENST00000399503.3:c.1978G>A p.Ala660Thr p.A660T ENST00000399503 NM_005921.1 660 Gcc/Acc 0 +MAP3K1 UCSF GRCh37 5 56177605 56177605 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 91 186 0 ENST00000399503.3:c.2578G>A p.Ala860Thr p.A860T ENST00000399503 NM_005921.1 860 Gca/Aca 0 +MAP3K15 UCSF GRCh37 X 19444406 19444406 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 103 92 0 ENST00000338883.4:c.1222G>A p.Val408Ile p.V408I ENST00000338883 NM_001001671.3 408 Gtt/Att 0 +MAP3K4 UCSF GRCh37 6 161469930 161469930 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 52 135 0 ENST00000392142.4:c.626C>T p.Pro209Leu p.P209L ENST00000392142 NM_005922.2 209 cCt/cTt 0 +MAPK10 UCSF GRCh37 4 87022299 87022299 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 73 130 0 ENST00000359221.3:c.636G>A p.Arg212= p.R212= ENST00000359221 212 agG/agA 0 +MAPKAPK3 UCSF GRCh37 3 50655216 50655216 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 30 67 0 ENST00000446044.1:c.219+1G>A p.X73_splice ENST00000446044 NM_001243926.1 0 +MAPKBP1 UCSF GRCh37 15 42116180 42116180 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 64 166 0 ENST00000456763.2:c.4152C>T p.Asn1384= p.N1384= ENST00000456763 NM_001128608.1 1384 aaC/aaT 0 +MARCH6 UCSF GRCh37 5 10394868 10394868 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 26 64 0 ENST00000274140.5:c.832C>T p.Leu278= p.L278= ENST00000274140 NM_005885.3 278 Cta/Tta 0 +MARS2 UCSF GRCh37 2 198570902 198570902 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 59 136 0 ENST00000282276.6:c.773G>A p.Arg258Lys p.R258K ENST00000282276 NM_138395.3 258 aGa/aAa 0 +MAST3 UCSF GRCh37 19 18256562 18256562 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 14 32 0 ENST00000262811.6:c.2962G>A p.Asp988Asn p.D988N ENST00000262811 NM_015016.1 988 Gac/Aac 0 +MASTL UCSF GRCh37 10 27448577 27448577 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 247 87 200 0 ENST00000375940.4:c.354C>T p.Val118= p.V118= ENST00000375940 118 gtC/gtT 0 +MATR3 UCSF GRCh37 5 138657666 138657666 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 75 190 0 ENST00000394805.3:c.1682G>A p.Gly561Glu p.G561E ENST00000394805 NM_001194955.1 561 gGg/gAg 0 +MAVS UCSF GRCh37 20 3845391 3845391 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0015 P18_Rec Untested WXS Illumina HiSeq 88 71 143 0 ENST00000428216.2:c.1114G>A p.Val372Met p.V372M ENST00000428216 NM_020746.4 372 Gtg/Atg 0 +MBD3 UCSF GRCh37 19 1585198 1585198 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 17 31 0 ENST00000156825.1:c.126G>A p.Lys42= p.K42= ENST00000156825 42 aaG/aaA 0 +MBD6 UCSF GRCh37 12 57918856 57918856 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 44 112 0 ENST00000355673.3:c.337C>T p.Leu113= p.L113= ENST00000355673 NM_052897.3 113 Ctg/Ttg 0 +MBNL3 UCSF GRCh37 X 131540357 131540357 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 64 86 0 ENST00000370853.3:c.241G>A p.Glu81Lys p.E81K ENST00000370853 NM_018388.3 81 Gag/Aag 0 +MBOAT7 UCSF GRCh37 19 54677978 54677978 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 64 122 0 ENST00000245615.1:c.1179G>A p.Lys393= p.K393= ENST00000245615 NM_024298.3 393 aaG/aaA 0 +MCCC2 UCSF GRCh37 5 70948514 70948514 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 47 133 0 ENST00000340941.6:c.1507G>A p.Ala503Thr p.A503T ENST00000340941 NM_022132.4 503 Gcg/Acg 0 +MCHR2 UCSF GRCh37 6 100395771 100395771 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 96 251 0 ENST00000281806.2:c.259C>T p.Pro87Ser p.P87S ENST00000281806 NM_001040179.1 87 Cct/Tct 0 +MCM3 UCSF GRCh37 6 52141149 52141149 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 34 83 0 ENST00000596288.1:c.1426G>A p.Val476Met p.V476M ENST00000596288 NM_002388.4 476 Gtg/Atg 0 +MDH2 UCSF GRCh37 7 75686800 75686800 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 48 100 0 ENST00000315758.5:c.308C>T p.Pro103Leu p.P103L ENST00000315758 NM_005918.2 103 cCc/cTc 0 +MDN1 UCSF GRCh37 6 90402360 90402360 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 111 228 0 ENST00000369393.3:c.10389G>A p.Lys3463= p.K3463= ENST00000369393 3463 aaG/aaA 0 +MED11 UCSF GRCh37 17 4636437 4636437 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 53 87 0 ENST00000293777.5:c.309G>A p.Lys103= p.K103= ENST00000293777 NM_001001683.2 103 aaG/aaA 0 +MED13 UCSF GRCh37 17 60042453 60042453 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 57 132 0 ENST00000397786.2:c.4758G>A p.Gly1586= p.G1586= ENST00000397786 NM_005121.2 1586 ggG/ggA 0 +MED13L UCSF GRCh37 12 116429432 116429432 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 46 131 0 ENST00000281928.3:c.3327C>T p.Leu1109= p.L1109= ENST00000281928 NM_015335.4 1109 ctC/ctT 0 +MED27 UCSF GRCh37 9 134889740 134889740 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 68 110 0 ENST00000292035.5:c.463C>T p.Leu155Phe p.L155F ENST00000292035 NM_004269.3 155 Ctt/Ttt 0 +MED27 UCSF GRCh37 9 134889742 134889742 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 59 109 0 ENST00000292035.5:c.461C>T p.Thr154Ile p.T154I ENST00000292035 NM_004269.3 154 aCt/aTt 0 +MED28 UCSF GRCh37 4 17625266 17625266 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 62 144 0 ENST00000237380.7:c.382C>T p.Leu128= p.L128= ENST00000237380 NM_025205.3 128 Cta/Tta 0 +MED4 UCSF GRCh37 13 48669160 48669160 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 27 58 0 ENST00000258648.2:c.55G>A p.Gly19Arg p.G19R ENST00000258648 NM_014166.3 19 Gga/Aga 0 +MED4 UCSF GRCh37 13 48669152 48669152 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 30 45 0 ENST00000258648.2:c.63G>A p.Ala21= p.A21= ENST00000258648 NM_014166.3 21 gcG/gcA 0 +MEGF6 UCSF GRCh37 1 3407119 3407119 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 9 33 0 ENST00000356575.4:c.4599C>T p.Ser1533= p.S1533= ENST00000356575 NM_001409.3 1533 tcC/tcT 0 +MEGF8 UCSF GRCh37 19 42860343 42860343 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 7 27 0 ENST00000334370.4:c.4300G>A p.Ala1434Thr p.A1434T ENST00000334370 NM_001410.2 1434 Gcc/Acc 0 +MEOX2 UCSF GRCh37 7 15725839 15725839 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 11 32 0 ENST00000262041.5:c.189G>A p.Gln63= p.Q63= ENST00000262041 NM_005924.4 63 caG/caA 0 +MEP1A UCSF GRCh37 6 46797172 46797172 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 144 105 216 0 ENST00000230588.4:c.1008C>T p.Tyr336= p.Y336= ENST00000230588 NM_005588.2 336 taC/taT 0 +MEPCE UCSF GRCh37 7 100030654 100030654 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 83 176 0 ENST00000310512.2:c.1784G>A p.Gly595Asp p.G595D ENST00000310512 NM_019606.5 595 gGc/gAc 0 +METTL22 UCSF GRCh37 16 8722649 8722649 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 62 130 1 ENST00000381920.3:c.196G>A p.Gly66Ser p.G66S ENST00000381920 NM_024109.2 66 Ggt/Agt 0 +METTL3 UCSF GRCh37 14 21967728 21967728 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 99 207 0 ENST00000298717.4:c.1360G>A p.Glu454Lys p.E454K ENST00000298717 NM_019852.3 454 Gaa/Aaa 0 +MEX3C UCSF GRCh37 18 48703067 48703067 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 110 218 0 ENST00000406189.3:c.1634C>T p.Ser545Phe p.S545F ENST00000406189 NM_016626.4 545 tCt/tTt 0 +MFRP UCSF GRCh37 11 119215654 119215654 + synonymous_variant,NMD_transcript_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 6 24 0 ENST00000530681.1:c.702C>T p.Val234= p.V234= ENST00000530681 234 gtC/gtT 0 +MGA UCSF GRCh37 15 42041421 42041421 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 227 176 332 0 ENST00000219905.7:c.5616G>A p.Gly1872= p.G1872= ENST00000219905 NM_001164273.1 1872 ggG/ggA 0 +MGMT UCSF GRCh37 10 131506280 131506280 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 87 173 0 ENST00000306010.7:c.340G>A p.Ala114Thr p.A114T ENST00000306010 NM_002412.3 114 Gct/Act 0 +MGRN1 UCSF GRCh37 16 4732837 4732837 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 15 51 0 ENST00000262370.7:c.1372C>T p.Pro458Ser p.P458S ENST00000262370 NM_015246.3 458 Ccg/Tcg 0 +MGRN1 UCSF GRCh37 16 4730053 4730053 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 45 103 0 ENST00000262370.7:c.1086G>A p.Lys362= p.K362= ENST00000262370 NM_015246.3 362 aaG/aaA 0 +MGST1 UCSF GRCh37 12 16510545 16510545 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 41 106 0 ENST00000396209.1:c.133G>A p.Ala45Thr p.A45T ENST00000396209 NM_145791.2 45 Gcc/Acc 0 +MIA3 UCSF GRCh37 1 222826618 222826618 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 72 164 0 ENST00000344922.5:c.4258G>A p.Glu1420Lys p.E1420K ENST00000344922 NM_198551.2 1420 Gaa/Aaa 0 +MIA3 UCSF GRCh37 1 222802863 222802863 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 69 168 0 ENST00000344922.5:c.2301G>A p.Gly767= p.G767= ENST00000344922 NM_198551.2 767 ggG/ggA 0 +MID2 UCSF GRCh37 X 107084129 107084129 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 111 120 0 ENST00000262843.6:c.234C>T p.Thr78= p.T78= ENST00000262843 NM_052817.2 78 acC/acT 0 +MIER1 UCSF GRCh37 1 67396083 67396083 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 17 39 0 ENST00000401041.1:c.168+4158G>A *56* ENST00000401041 NM_001077700.2 0 +MIER2 UCSF GRCh37 19 327170 327170 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 103 187 0 ENST00000264819.4:c.456C>T p.Ser152= p.S152= ENST00000264819 NM_017550.1 152 tcC/tcT 0 +MKI67 UCSF GRCh37 10 129911709 129911709 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 150 89 219 0 ENST00000368654.3:c.1638C>T p.Val546= p.V546= ENST00000368654 NM_002417.4 546 gtC/gtT 0 +MKL2 UCSF GRCh37 16 14340383 14340383 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 154 73 141 0 ENST00000318282.5:c.1266C>T p.Thr422= p.T422= ENST00000318282 422 acC/acT 0 +MLL UCSF GRCh37 11 118360597 118360597 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 85 141 0 ENST00000534358.1:c.4570G>A p.Val1524Ile p.V1524I ENST00000534358 NM_005933.3 1524 Gtc/Atc 0 +MLL2 UCSF GRCh37 12 49431402 49431402 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 9 32 60 0 ENST00000301067.7:c.9737C>T p.Pro3246Leu p.P3246L ENST00000301067 NM_003482.3 3246 cCc/cTc 0 +MLL2 UCSF GRCh37 12 49431257 49431257 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 25 78 0 ENST00000301067.7:c.9882C>T p.Ala3294= p.A3294= ENST00000301067 NM_003482.3 3294 gcC/gcT 0 +MLL3 UCSF GRCh37 7 151875061 151875061 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 45 119 0 ENST00000262189.6:c.7477C>T p.Pro2493Ser p.P2493S ENST00000262189 NM_170606.2 2493 Ccg/Tcg 0 +MLL4 UCSF GRCh37 19 36218834 36218834 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 17 21 0 ENST00000222270.7:c.4445G>A p.Gly1482Glu p.G1482E ENST00000222270 NM_014727.1 1482 gGa/gAa 0 +MLL4 UCSF GRCh37 19 36220182 36220182 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 25 50 0 ENST00000222270.7:c.4902C>T p.Ala1634= p.A1634= ENST00000222270 NM_014727.1 1634 gcC/gcT 0 +MLL4 UCSF GRCh37 19 36221731 36221731 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 20 76 0 ENST00000222270.7:c.5400G>A p.Glu1800= p.E1800= ENST00000222270 NM_014727.1 1800 gaG/gaA 0 +MLLT10 UCSF GRCh37 10 21827796 21827796 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.300,1000g2011may_all_0.31727,snp132_rs1802669 P18_Rec Untested WXS Illumina HiSeq 194 83 148 0 ENST00000307729.7:c.195G>A p.Pro65= p.P65= ENST00000307729 65 ccG/ccA 0 +MLPH UCSF GRCh37 2 238419422 238419422 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 18 74 0 ENST00000264605.3:c.316C>T p.Pro106Ser p.P106S ENST00000264605 NM_024101.6 106 Ccc/Tcc 0 +MMAA UCSF GRCh37 4 146567273 146567273 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 156 110 248 0 ENST00000281317.5:c.698G>A p.Gly233Glu p.G233E ENST00000281317 NM_172250.2 233 gGa/gAa 0 +MMACHC UCSF GRCh37 1 45974779 45974779 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 124 222 0 ENST00000401061.4:c.741C>T p.Ser247= p.S247= ENST00000401061 NM_015506.2 247 tcC/tcT 0 +MME UCSF GRCh37 3 154884718 154884718 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 121 200 0 ENST00000460393.1:c.1688C>T p.Pro563Leu p.P563L ENST00000460393 NM_007287.2 563 cCc/cTc 0 +MMP24 UCSF GRCh37 20 33842359 33842359 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 227 191 363 0 ENST00000246186.6:c.619C>T p.Pro207Ser p.P207S ENST00000246186 NM_006690.3 207 Cca/Tca 0 +MMP7 UCSF GRCh37 11 102398543 102398543 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 97 237 0 ENST00000260227.4:c.280G>A p.Glu94Lys p.E94K ENST00000260227 NM_002423.3 94 Gaa/Aaa 0 +MMP8 UCSF GRCh37 11 102584500 102584500 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 170 101 250 0 ENST00000236826.3:c.1279G>A p.Val427Ile p.V427I ENST00000236826 NM_002424.2 427 Gtt/Att 0 +MOGAT3 UCSF GRCh37 7 100841566 100841566 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 33 57 0 ENST00000223114.4:c.574G>A p.Gly192Arg p.G192R ENST00000223114 NM_178176.2 192 Ggg/Agg 0 +MORN4 UCSF GRCh37 10 99379358 99379358 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 111 232 0 ENST00000307450.6:c.53G>A p.Gly18Asp p.G18D ENST00000307450 NM_178832.3 18 gGc/gAc 0 +MORN5 UCSF GRCh37 9 124922265 124922265 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 49 152 0 ENST00000373764.3:c.14G>A p.Gly5Glu p.G5E ENST00000373764 NM_198469.2 5 gGg/gAg 0 +MOSC1 UCSF GRCh37 1 220971342 220971342 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.00182 P18_Rec somatic WXS Sanger Illumina HiSeq 196 167 298 0 ENST00000366910.5:c.739G>A p.Asp247Asn p.D247N ENST00000366910 NM_022746.3 247 Gat/Aat 0 +MPDZ UCSF GRCh37 9 13110053 13110053 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 119 210 0 ENST00000541718.1:c.5753G>A p.Gly1918Glu p.G1918E ENST00000541718 NM_001261407.1 1918 gGa/gAa 0 +MPO UCSF GRCh37 17 56350997 56350997 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 77 162 0 ENST00000225275.3:c.1399C>T p.Leu467= p.L467= ENST00000225275 NM_000250.1 467 Ctg/Ttg 0 +MRFAP1 UCSF GRCh37 4 6642626 6642626 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 102 166 0 ENST00000320912.4:c.37G>A p.Glu13Lys p.E13K ENST00000320912 NM_001272053.1 13 Gag/Aag 0 +MRPL14 UCSF GRCh37 6 44084277 44084277 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 155 112 234 0 ENST00000372014.3:c.71+1G>A p.X24_splice ENST00000372014 NM_032111.2 0 +MRPL34 UCSF GRCh37 19 17417154 17417154 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 6 25 0 ENST00000252602.1:c.245G>A p.Arg82Gln p.R82Q ENST00000252602 NM_023937.3 82 cGa/cAa 0 +MRPL36 UCSF GRCh37 5 1798955 1798955 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 39 123 0 ENST00000508987.1:c.95G>A p.Gly32Glu p.G32E ENST00000508987 32 gGa/gAa 0 +MRPL52 UCSF GRCh37 14 23299290 23299290 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 35 76 0 ENST00000355151.5:c.60C>T p.Ala20= p.A20= ENST00000355151 NM_181306.2 20 gcC/gcT 0 +MRPL9 UCSF GRCh37 1 151732528 151732528 + stop_lost Nonstop_Mutation SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 52 104 0 ENST00000368830.3:c.802T>A p.Ter268LysextTer23 p.*268Kext*23 ENST00000368830 NM_031420.2 268 Taa/Aaa 0 +MRPS16 UCSF GRCh37 10 75011752 75011752 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 34 59 0 ENST00000372945.3:c.43G>A p.Gly15Ser p.G15S ENST00000372945 NM_016065.3 15 Ggc/Agc 0 +MRPS18B UCSF GRCh37 6 30593558 30593558 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 66 132 0 ENST00000259873.4:c.761C>T p.Pro254Leu p.P254L ENST00000259873 NM_014046.3 254 cCt/cTt 0 +MRPS18B UCSF GRCh37 6 30587270 30587270 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 68 120 0 ENST00000259873.4:c.79G>A p.Val27Ile p.V27I ENST00000259873 NM_014046.3 27 Gtt/Att 0 +MRPS5 UCSF GRCh37 2 95773982 95773982 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 78 158 0 ENST00000272418.2:c.575G>A p.Gly192Glu p.G192E ENST00000272418 NM_031902.3 192 gGa/gAa 0 +MS4A6E UCSF GRCh37 11 60105419 60105419 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 47 137 0 ENST00000300182.4:c.353C>T p.Ala118Val p.A118V ENST00000300182 NM_139249.2 118 gCt/gTt 0 +MSH2 UCSF GRCh37 2 47709944 47709944 + synonymous_variant Silent SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 16 56 125 0 ENST00000233146.2:c.2661C>T p.Phe887= p.F887= ENST00000233146 NM_000251.2 887 ttC/ttT 0 +MSH3 UCSF GRCh37 5 79974745 79974745 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 159 94 193 0 ENST00000265081.6:c.1174-1G>A p.X392_splice ENST00000265081 NM_002439.4 0 +MSH5 UCSF GRCh37 6 31713013 31713013 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 72 53 118 0 ENST00000375703.3:c.684-1G>A p.X228_splice ENST00000375703 0 +MSLNL UCSF GRCh37 16 830474 830474 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 203 75 196 0 ENST00000293892.3:c.527C>T p.Pro176Leu p.P176L ENST00000293892 176 cCt/cTt 0 +MST4 UCSF GRCh37 X 131206346 131206346 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 44 63 0 ENST00000394334.2:c.983C>T p.Thr328Ile p.T328I ENST00000394334 NM_016542.3 328 aCc/aTc 0 +MTA1 UCSF GRCh37 14 105927194 105927194 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 31 60 0 ENST00000331320.7:c.846G>A p.Arg282= p.R282= ENST00000331320 NM_004689.3 282 agG/agA 0 +MTA2 UCSF GRCh37 11 62361989 62361989 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 84 183 0 ENST00000278823.2:c.1691C>T p.Thr564Ile p.T564I ENST00000278823 NM_004739.3 564 aCt/aTt 0 +MTF1 UCSF GRCh37 1 38280883 38280883 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 65 138 0 ENST00000373036.4:c.2187G>A p.Pro729= p.P729= ENST00000373036 NM_005955.2 729 ccG/ccA 0 +MTL5 UCSF GRCh37 11 68518092 68518092 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 5 22 0 ENST00000255087.5:c.37C>T p.Pro13Ser p.P13S ENST00000255087 NM_004923.3 13 Ccc/Tcc 0 +MTMR3 UCSF GRCh37 22 30394841 30394841 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 0 25 44 0 ENST00000401950.2:c.552G>A p.Lys184= p.K184= ENST00000401950 NM_021090.3 184 aaG/aaA 0 +MTR UCSF GRCh37 1 237001873 237001873 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 75 153 0 ENST00000366577.5:c.1489G>A p.Val497Ile p.V497I ENST00000366577 NM_000254.2 497 Gtc/Atc 0 +MTSS1L UCSF GRCh37 16 70698214 70698214 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 13 16 0 ENST00000338779.6:c.1610C>T p.Ala537Val p.A537V ENST00000338779 NM_138383.2 537 gCc/gTc 0 +MTSS1L UCSF GRCh37 16 70698015 70698015 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 8 19 0 ENST00000338779.6:c.1809C>T p.Gly603= p.G603= ENST00000338779 NM_138383.2 603 ggC/ggT 0 +MTUS1 UCSF GRCh37 8 17612340 17612340 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 193 121 283 0 ENST00000262102.6:c.977G>A p.Ser326Asn p.S326N ENST00000262102 NM_001001924.2 326 aGc/aAc 0 +MTUS1 UCSF GRCh37 8 17612346 17612346 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 117 273 0 ENST00000262102.6:c.971C>T p.Ser324Leu p.S324L ENST00000262102 NM_001001924.2 324 tCa/tTa 0 +MTX2 UCSF GRCh37 2 177193039 177193039 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 146 110 193 0 ENST00000249442.6:c.304G>A p.Gly102Arg p.G102R ENST00000249442 NM_006554.4 102 Ggg/Agg 0 +MUC12 UCSF GRCh37 7 100644479 100644479 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 351 160 480 0 ENST00000536621.1:c.10635G>A p.Gln3545= p.Q3545= ENST00000536621 NM_001164462.1 3545 caG/caA 0 +MUC13 UCSF GRCh37 3 124646780 124646780 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 127 95 189 0 ENST00000311075.3:c.110G>A p.Gly37Asp p.G37D ENST00000311075 NM_033049.3 37 gGt/gAt 0 +MUC13 UCSF GRCh37 3 124646678 124646678 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 203 155 301 0 ENST00000311075.3:c.212C>T p.Pro71Leu p.P71L ENST00000311075 NM_033049.3 71 cCc/cTc 0 +MUC16 UCSF GRCh37 19 8993478 8993478 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 143 106 219 0 ENST00000397910.4:c.41611C>T p.Pro13871Ser p.P13871S ENST00000397910 NM_024690.2 13871 Cct/Tct 0 +MUC16 UCSF GRCh37 19 9049298 9049298 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 244 185 382 0 ENST00000397910.4:c.32333C>T p.Ser10778Leu p.S10778L ENST00000397910 NM_024690.2 10778 tCg/tTg 0 +MUC16 UCSF GRCh37 19 9061560 9061560 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.024,1000g2011may_all_0.0668,snp132_rs56807558 P18_Rec Untested WXS Illumina HiSeq 212 49 324 0 ENST00000397910.4:c.25886C>T p.Thr8629Met p.T8629M ENST00000397910 NM_024690.2 8629 aCg/aTg 0 +MUC16 UCSF GRCh37 19 9066635 9066635 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 247 194 388 0 ENST00000397910.4:c.20811G>A p.Glu6937= p.E6937= ENST00000397910 NM_024690.2 6937 gaG/gaA 0 +MUC16 UCSF GRCh37 19 9061022 9061022 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 223 145 306 0 ENST00000397910.4:c.26424C>T p.Ser8808= p.S8808= ENST00000397910 NM_024690.2 8808 agC/agT 0 +MUC16 UCSF GRCh37 19 9066128 9066128 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 166 127 290 0 ENST00000397910.4:c.21318C>T p.Thr7106= p.T7106= ENST00000397910 NM_024690.2 7106 acC/acT 0 +MUC17 UCSF GRCh37 7 100696713 100696713 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 24 80 0 ENST00000306151.4:c.13359C>T p.Cys4453= p.C4453= ENST00000306151 NM_001040105.1 4453 tgC/tgT 0 +MUC17 UCSF GRCh37 7 100678195 100678195 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 257 176 371 0 ENST00000306151.4:c.3498T>C p.Pro1166= p.P1166= ENST00000306151 NM_001040105.1 1166 ccT/ccC 0 +MUC4 UCSF GRCh37 3 195513137 195513137 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 694 100 828 0 ENST00000463781.3:c.5314G>A p.Ala1772Thr p.A1772T ENST00000463781 NM_018406.6 1772 Gct/Act 0 +MUC4 UCSF GRCh37 3 195513194 195513194 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 451 167 617 0 ENST00000463781.3:c.5257G>A p.Ala1753Thr p.A1753T ENST00000463781 NM_018406.6 1753 Gca/Aca 0 +MVP UCSF GRCh37 16 29856151 29856151 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 77 149 0 ENST00000357402.5:c.1972G>A p.Val658Ile p.V658I ENST00000357402 NM_017458.3 658 Gtc/Atc 0 +MVP UCSF GRCh37 16 29842379 29842379 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 19 43 0 ENST00000357402.5:c.306G>A p.Gly102= p.G102= ENST00000357402 NM_017458.3 102 ggG/ggA 0 +MYBBP1A UCSF GRCh37 17 4455460 4455460 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 53 104 0 ENST00000381556.2:c.865G>A p.Val289Met p.V289M ENST00000381556 NM_014520.3 289 Gtg/Atg 0 +MYBPC1 UCSF GRCh37 12 102036311 102036311 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 30 54 0 ENST00000452455.2:c.705C>T p.Arg235= p.R235= ENST00000452455 NM_001254718.1 235 cgC/cgT 0 +MYBPC2 UCSF GRCh37 19 50944141 50944141 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 26 55 0 ENST00000357701.5:c.577G>A p.Val193Met p.V193M ENST00000357701 NM_004533.3 193 Gtg/Atg 0 +MYCBP2 UCSF GRCh37 13 77635855 77635855 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 30 112 0 ENST00000544440.2:c.12731G>A p.Cys4244Tyr p.C4244Y ENST00000544440 4244 tGt/tAt 0 +MYCBP2 UCSF GRCh37 13 77669565 77669565 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 58 137 0 ENST00000544440.2:c.10013C>T p.Pro3338Leu p.P3338L ENST00000544440 3338 cCc/cTc 0 +MYCBP2 UCSF GRCh37 13 77763129 77763129 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 55 178 0 ENST00000544440.2:c.4094C>T p.Pro1365Leu p.P1365L ENST00000544440 1365 cCt/cTt 0 +MYH10 UCSF GRCh37 17 8381764 8381764 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 47 133 0 ENST00000360416.3:c.5598G>A p.Lys1866= p.K1866= ENST00000360416 NM_001256012.1 1866 aaG/aaA 0 +MYH13 UCSF GRCh37 17 10231375 10231375 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 68 163 0 ENST00000418404.3:c.2499G>A p.Trp833Ter p.W833* ENST00000418404 833 tgG/tgA 0 +MYH13 UCSF GRCh37 17 10212743 10212743 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 18 21 34 0 ENST00000418404.3:c.4977G>A p.Leu1659= p.L1659= ENST00000418404 1659 ctG/ctA 0 +MYH15 UCSF GRCh37 3 108156540 108156540 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 142 106 246 0 ENST00000273353.3:c.3142G>A p.Gly1048Ser p.G1048S ENST00000273353 NM_014981.1 1048 Ggt/Agt 0 +MYH2 UCSF GRCh37 17 10447245 10447245 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 174 124 272 0 ENST00000245503.5:c.622G>A p.Glu208Lys p.E208K ENST00000245503 NM_017534.5 208 Gaa/Aaa 0 +MYH3 UCSF GRCh37 17 10533424 10533424 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 181 120 253 0 ENST00000583535.1:c.5547G>A p.Lys1849= p.K1849= ENST00000583535 NM_002470.3 1849 aaG/aaA 0 +MYH4 UCSF GRCh37 17 10353882 10353882 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 106 90 168 1 ENST00000255381.2:c.4069G>A p.Ala1357Thr p.A1357T ENST00000255381 NM_017533.2 1357 Gcc/Acc 0 +MYH4 UCSF GRCh37 17 10355605 10355605 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 90 205 0 ENST00000255381.2:c.3391G>A p.Ala1131Thr p.A1131T ENST00000255381 NM_017533.2 1131 Gcc/Acc 0 +MYH4 UCSF GRCh37 17 10348301 10348301 + stop_gained Nonsense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 113 226 0 ENST00000255381.2:c.5458G>T p.Glu1820Ter p.E1820* ENST00000255381 NM_017533.2 1820 Gag/Tag 0 +MYH6 UCSF GRCh37 14 23868031 23868031 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 77 162 0 ENST00000405093.3:c.1797G>A p.Lys599= p.K599= ENST00000405093 NM_002471.3 599 aaG/aaA 0 +MYH9 UCSF GRCh37 22 36684872 36684872 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 82 170 0 ENST00000216181.5:c.4671G>A p.Arg1557= p.R1557= ENST00000216181 NM_002473.4 1557 cgG/cgA 0 +MYL1 UCSF GRCh37 2 211163168 211163168 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 65 179 0 ENST00000352451.3:c.280G>T p.Val94Phe p.V94F ENST00000352451 NM_079420.2 94 Gtt/Ttt 0 +MYL12B UCSF GRCh37 18 3277370 3277370 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 123 194 0 ENST00000581193.1:c.304G>A p.Val102Ile p.V102I ENST00000581193 NM_001144945.1 102 Gtc/Atc 0 +MYLK UCSF GRCh37 3 123383000 123383000 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 135 84 220 0 ENST00000360304.3:c.3937G>A p.Glu1313Lys p.E1313K ENST00000360304 NM_053025.3 1313 Gag/Aag 0 +MYO18A UCSF GRCh37 17 27417083 27417083 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 47 153 0 ENST00000527372.1:c.5422G>A p.Glu1808Lys p.E1808K ENST00000527372 NM_078471.3 1808 Gag/Aag 0 +MYO1F UCSF GRCh37 19 8616672 8616672 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 70 132 0 ENST00000338257.8:c.723C>T p.Thr241= p.T241= ENST00000338257 NM_012335.3 241 acC/acT 0 +MYO5C UCSF GRCh37 15 52548869 52548869 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 95 214 0 ENST00000261839.7:c.1362C>T p.Tyr454= p.Y454= ENST00000261839 NM_018728.3 454 taC/taT 0 +MYO9A UCSF GRCh37 15 72190819 72190819 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 129 252 0 ENST00000356056.5:c.4025G>A p.Ser1342Asn p.S1342N ENST00000356056 NM_006901.3 1342 aGc/aAc 0 +MYO9B UCSF GRCh37 19 17273863 17273863 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 55 103 0 ENST00000595618.1:c.1602G>A p.Gln534= p.Q534= ENST00000595618 NM_001130065.1 534 caG/caA 0 +MYOC UCSF GRCh37 1 171605628 171605628 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 82 160 0 ENST00000037502.6:c.952C>T p.Leu318= p.L318= ENST00000037502 NM_000261.1 318 Ctg/Ttg 0 +MYOF UCSF GRCh37 10 95097607 95097607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 159 85 232 0 ENST00000359263.4:c.4402G>A p.Gly1468Arg p.G1468R ENST00000359263 NM_013451.3 1468 Gga/Aga 0 +MYOF UCSF GRCh37 10 95069906 95069906 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 56 109 0 ENST00000359263.4:c.6018C>T p.Phe2006= p.F2006= ENST00000359263 NM_013451.3 2006 ttC/ttT 0 +MYOM1 UCSF GRCh37 18 3188831 3188831 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 62 151 0 ENST00000356443.4:c.686C>T p.Ala229Val p.A229V ENST00000356443 NM_019856.1 229 gCt/gTt 0 +MYOM1 UCSF GRCh37 18 3151867 3151867 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 165 97 251 0 ENST00000356443.4:c.1668G>A p.Trp556Ter p.W556* ENST00000356443 NM_019856.1 556 tgG/tgA 0 +MYOM1 UCSF GRCh37 18 3215153 3215153 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 37 107 0 ENST00000356443.4:c.69C>T p.Arg23= p.R23= ENST00000356443 NM_019856.1 23 cgC/cgT 0 +MYOZ3 UCSF GRCh37 5 150056363 150056363 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 86 63 177 0 ENST00000297130.4:c.682C>T p.Leu228Phe p.L228F ENST00000297130 NM_133371.4 228 Ctc/Ttc 0 +MYT1 UCSF GRCh37 20 62839012 62839012 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 74 151 0 ENST00000328439.1:c.463G>A p.Gly155Ser p.G155S ENST00000328439 NM_004535.2 155 Ggc/Agc 0 +MYT1L UCSF GRCh37 2 1796216 1796216 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 46 98 0 ENST00000428368.2:c.3291C>T p.Asn1097= p.N1097= ENST00000428368 1097 aaC/aaT 0 +MZF1 UCSF GRCh37 19 59074195 59074195 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 6 9 12 0 ENST00000215057.2:c.1449C>T p.Gly483= p.G483= ENST00000215057 NM_001267033.1 483 ggC/ggT 0 +N4BP2 UCSF GRCh37 4 40103856 40103856 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 157 119 289 0 ENST00000261435.6:c.391G>A p.Asp131Asn p.D131N ENST00000261435 NM_018177.4 131 Gat/Aat 0 +N4BP2 UCSF GRCh37 4 40119559 40119559 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 73 174 0 ENST00000261435.6:c.1735G>A p.Val579Met p.V579M ENST00000261435 NM_018177.4 579 Gtg/Atg 0 +NAA16 UCSF GRCh37 13 41894911 41894911 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 42 150 0 ENST00000379406.3:c.353G>A p.Arg118Lys p.R118K ENST00000379406 NM_024561.4 118 aGg/aAg 0 +NAA35 UCSF GRCh37 9 88593224 88593224 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 130 300 0 ENST00000361671.5:c.805G>A p.Ala269Thr p.A269T ENST00000361671 NM_024635.3 269 Gca/Aca 0 +NACAD UCSF GRCh37 7 45124894 45124894 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 6 13 0 ENST00000490531.2:c.885C>T p.Phe295= p.F295= ENST00000490531 NM_001146334.1 295 ttC/ttT 0 +NADSYN1 UCSF GRCh37 11 71183505 71183505 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 50 108 0 ENST00000319023.2:c.418G>A p.Glu140Lys p.E140K ENST00000319023 NM_018161.4 140 Gag/Aag 0 +NAPSA UCSF GRCh37 19 50861859 50861859 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 24 35 0 ENST00000253719.2:c.1214G>A p.Gly405Glu p.G405E ENST00000253719 NM_004851.1 405 gGa/gAa 0 +NASP UCSF GRCh37 1 46073426 46073426 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 40 111 0 ENST00000350030.3:c.843G>A p.Gln281= p.Q281= ENST00000350030 NM_002482.3 281 caG/caA 0 +NAT10 UCSF GRCh37 11 34153694 34153694 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 229 164 358 0 ENST00000257829.3:c.1543C>T p.Leu515Phe p.L515F ENST00000257829 NM_024662.2 515 Ctc/Ttc 0 +NAT8B UCSF GRCh37 2 73928149 73928149 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 138 257 0 ENST00000377712.2:n.284C>T *95* ENST00000377712 0 +NBEA UCSF GRCh37 13 35692373 35692373 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 27 84 0 ENST00000400445.3:c.2091G>A p.Gly697= p.G697= ENST00000400445 NM_015678.4 697 ggG/ggA 0 +NBPF14 UCSF GRCh37 1 148015760 148015760 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 256 156 423 0 ENST00000310701.10:c.888G>A p.Val297Ile p.V297I ENST00000310701 297 Gtc/Atc 0 +NBPF7 UCSF GRCh37 1 120382012 120382012 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 156 150 243 0 ENST00000401014.1:n.1254G>A *418* ENST00000401014 0 +NBPF9 UCSF GRCh37 1 144825474 144825474 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 290 146 467 0 ENST00000375552.4:c.1422G>A p.Ala475Thr p.A475T ENST00000375552 NM_001277444.1 475 Gct/Act 0 +NCAPH2 UCSF GRCh37 22 50956631 50956631 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 40 67 0 ENST00000299821.11:c.570G>A p.Gly190= p.G190= ENST00000299821 190 ggG/ggA 0 +NCKAP1L UCSF GRCh37 12 54905614 54905614 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 73 170 0 ENST00000293373.6:c.763G>A p.Val255Ile p.V255I ENST00000293373 NM_005337.4 255 Gta/Ata 0 +NCKAP5 UCSF GRCh37 2 133540839 133540839 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 153 108 264 0 ENST00000409261.1:c.3545C>T p.Ser1182Phe p.S1182F ENST00000409261 NM_207363.2 1182 tCc/tTc 0 +NCKIPSD UCSF GRCh37 3 48717086 48717086 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 62 147 0 ENST00000294129.2:c.1411G>A p.Asp471Asn p.D471N ENST00000294129 NM_016453.3 471 Gat/Aat 0 +NCOA1 UCSF GRCh37 2 24949505 24949505 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 80 155 0 ENST00000406961.1:c.2647C>T p.Pro883Ser p.P883S ENST00000406961 883 Cca/Tca 0 +NCOA2 UCSF GRCh37 8 71069245 71069245 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 110 94 190 0 ENST00000452400.2:c.1355G>A p.Gly452Asp p.G452D ENST00000452400 NM_006540.2 452 gGc/gAc 0 +NCOA3 UCSF GRCh37 20 46264805 46264805 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.018,1000g2011may_all_0.0462,snp132_rs2230781 P18_Rec Untested WXS Illumina HiSeq 107 96 208 0 ENST00000371998.3:c.1675C>T p.Pro559Ser p.P559S ENST00000371998 559 Cca/Tca 0 +NCOR2 UCSF GRCh37 12 124971028 124971028 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 13 29 0 ENST00000405201.1:c.192G>A p.Arg64= p.R64= ENST00000405201 64 cgG/cgA 0 +NCR1 UCSF GRCh37 19 55420876 55420876 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 50 106 0 ENST00000291890.4:c.628G>A p.Val210Ile p.V210I ENST00000291890 NM_004829.6 210 Gtc/Atc 0 +NDC80 UCSF GRCh37 18 2574999 2574999 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 52 113 0 ENST00000261597.4:c.113C>T p.Pro38Leu p.P38L ENST00000261597 NM_006101.2 38 cCa/cTa 0 +NDST1 UCSF GRCh37 5 149901129 149901129 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 72 156 0 ENST00000261797.6:c.313G>A p.Glu105Lys p.E105K ENST00000261797 NM_001543.4 105 Gag/Aag 0 +NDST4 UCSF GRCh37 4 115769441 115769441 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 83 196 0 ENST00000264363.2:c.1870C>T p.Leu624Phe p.L624F ENST00000264363 NM_022569.1 624 Ctc/Ttc 0 +NDUFS1 UCSF GRCh37 2 207011800 207011800 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 73 178 0 ENST00000455934.2:c.606G>A p.Glu202= p.E202= ENST00000455934 NM_001199984.1 202 gaG/gaA 0 +NDUFS8 UCSF GRCh37 11 67803812 67803812 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 35 48 0 ENST00000313468.5:c.465C>T p.Phe155= p.F155= ENST00000313468 NM_002496.3 155 ttC/ttT 0 +NEB UCSF GRCh37 2 152424671 152424671 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 75 178 0 ENST00000397345.3:c.17758G>A p.Glu5920Lys p.E5920K ENST00000397345 NM_001164508.1 5920 Gag/Aag 0 +NEB UCSF GRCh37 2 152477474 152477474 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 108 185 0 ENST00000397345.3:c.10519C>T p.Pro3507Ser p.P3507S ENST00000397345 NM_001164508.1 3507 Ccc/Tcc 0 +NEB UCSF GRCh37 2 152424833 152424833 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 89 174 0 ENST00000397345.3:c.17733C>T p.Asp5911= p.D5911= ENST00000397345 NM_001164508.1 5911 gaC/gaT 0 +NEB UCSF GRCh37 2 152468757 152468757 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 104 258 0 ENST00000397345.3:c.11748C>T p.Cys3916= p.C3916= ENST00000397345 NM_001164508.1 3916 tgC/tgT 0 +NEBL UCSF GRCh37 10 21134283 21134283 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 43 97 0 ENST00000377122.4:c.1131G>A p.Glu377= p.E377= ENST00000377122 NM_006393.2 377 gaG/gaA 0 +NECAB2 UCSF GRCh37 16 84005771 84005771 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 41 88 0 ENST00000305202.4:c.217G>A p.Asp73Asn p.D73N ENST00000305202 NM_019065.2 73 Gac/Aac 0 +NEO1 UCSF GRCh37 15 73528829 73528829 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 98 220 0 ENST00000339362.5:c.1433C>T p.Thr478Ile p.T478I ENST00000339362 478 aCc/aTc 0 +NETO1 UCSF GRCh37 18 70450940 70450940 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 105 189 0 ENST00000327305.6:c.841C>T p.Gln281Ter p.Q281* ENST00000327305 NM_138966.3 281 Cag/Tag 0 +NEURL4 UCSF GRCh37 17 7220873 7220873 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 69 52 111 0 ENST00000399464.2:c.4225G>A p.Ala1409Thr p.A1409T ENST00000399464 NM_032442.2 1409 Gct/Act 0 +NF1 UCSF GRCh37 17 29587442 29587442 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 182 98 247 0 ENST00000358273.4:c.4486C>T p.Leu1496Phe p.L1496F ENST00000358273 NM_001042492.2 1496 Ctt/Ttt 0 +NF1 UCSF GRCh37 17 29661958 29661958 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 124 73 159 0 ENST00000358273.4:c.5915C>T p.Thr1972Ile p.T1972I ENST00000358273 NM_001042492.2 1972 aCt/aTt 0 +NFATC2IP UCSF GRCh37 16 28965910 28965910 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 271 105 241 0 ENST00000320805.4:c.485G>A p.Gly162Asp p.G162D ENST00000320805 NM_032815.3 162 gGt/gAt 0 +NFIX UCSF GRCh37 19 13192670 13192670 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 35 74 0 ENST00000397661.2:c.1254+1G>A p.X418_splice ENST00000397661 NM_002501.2 0 +NFIX UCSF GRCh37 19 13136017 13136017 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 67 162 0 ENST00000397661.2:c.210G>A p.Lys70= p.K70= ENST00000397661 NM_002501.2 70 aaG/aaA 0 +NGEF UCSF GRCh37 2 233748155 233748155 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 10 36 0 ENST00000264051.3:c.1623C>T p.Asp541= p.D541= ENST00000264051 NM_019850.2 541 gaC/gaT 0 +NGEF UCSF GRCh37 2 233839466 233839466 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 153 137 246 0 ENST00000264051.3:c.135C>T p.Asp45= p.D45= ENST00000264051 NM_019850.2 45 gaC/gaT 0 +NHSL1 UCSF GRCh37 6 138752305 138752305 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 38 93 0 ENST00000427025.2:c.3189G>A p.Glu1063= p.E1063= ENST00000427025 NM_020464.1 1063 gaG/gaA 0 +NID2 UCSF GRCh37 14 52527059 52527059 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 32 53 0 ENST00000216286.5:c.550G>A p.Ala184Thr p.A184T ENST00000216286 NM_007361.3 184 Gca/Aca 0 +NIPSNAP1 UCSF GRCh37 22 29966495 29966495 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 23 63 0 ENST00000216121.7:c.125G>A p.Ser42Asn p.S42N ENST00000216121 NM_001202502.1 42 aGc/aAc 0 +NISCH UCSF GRCh37 3 52514312 52514312 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 40 83 0 ENST00000345716.4:c.1528+1G>A p.X510_splice ENST00000345716 NM_007184.3 0 +NLRC5 UCSF GRCh37 16 57111876 57111876 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 16 44 0 ENST00000262510.6:c.5025G>A p.Gly1675= p.G1675= ENST00000262510 NM_032206.4 1675 ggG/ggA 0 +NMUR1 UCSF GRCh37 2 232390053 232390053 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 31 74 0 ENST00000305141.4:c.982G>A p.Asp328Asn p.D328N ENST00000305141 NM_006056.4 328 Gat/Aat 0 +NNT UCSF GRCh37 5 43653298 43653298 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 40 71 0 ENST00000264663.5:c.2042C>T p.Ala681Val p.A681V ENST00000264663 NM_012343.3 681 gCt/gTt 0 +NOD2 UCSF GRCh37 16 50733518 50733518 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 59 136 0 ENST00000300589.2:c.193G>A p.Val65Ile p.V65I ENST00000300589 NM_022162.1 65 Gtc/Atc 0 +NOL11 UCSF GRCh37 17 65720295 65720295 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 70 126 0 ENST00000253247.4:c.650C>T p.Ser217Phe p.S217F ENST00000253247 NM_015462.3 217 tCt/tTt 0 +NOL11 UCSF GRCh37 17 65733707 65733707 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 119 267 0 ENST00000253247.4:c.1302G>A p.Gly434= p.G434= ENST00000253247 NM_015462.3 434 ggG/ggA 0 +NOL11 UCSF GRCh37 17 65734319 65734319 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 77 156 0 ENST00000253247.4:c.1611G>A p.Glu537= p.E537= ENST00000253247 NM_015462.3 537 gaG/gaA 0 +NOL8 UCSF GRCh37 9 95060548 95060548 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 39 85 0 ENST00000545558.1:c.3444C>T p.Asn1148= p.N1148= ENST00000545558 1148 aaC/aaT 0 +NOP16 UCSF GRCh37 5 175812280 175812280 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 59 164 0 ENST00000510123.1:c.335C>T p.Ser112Phe p.S112F ENST00000510123 NM_001256539.1 112 tCt/tTt 0 +NOTCH4 UCSF GRCh37 6 32168681 32168681 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 12 45 0 ENST00000375023.3:c.4242G>A p.Ala1414= p.A1414= ENST00000375023 NM_004557.3 1414 gcG/gcA 0 +NOX4 UCSF GRCh37 11 89069061 89069061 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 76 147 0 ENST00000263317.4:c.1568G>A p.Arg523His p.R523H ENST00000263317 523 cGt/cAt 0 +NPEPL1 UCSF GRCh37 20 57276164 57276164 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 28 34 0 ENST00000356091.6:c.772G>A p.Val258Met p.V258M ENST00000356091 NM_024663.3 258 Gtg/Atg 0 +NPEPPS UCSF GRCh37 17 45673785 45673785 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 49 134 0 ENST00000322157.4:c.1493C>T p.Thr498Ile p.T498I ENST00000322157 NM_006310.3 498 aCc/aTc 0 +NPFFR2 UCSF GRCh37 4 72897682 72897682 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 42 87 0 ENST00000308744.6:c.64G>A p.Ala22Thr p.A22T ENST00000308744 NM_004885.2 22 Gca/Aca 0 +NPHP3 UCSF GRCh37 3 132435724 132435724 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 79 159 0 ENST00000337331.5:c.700G>A p.Gly234Ser p.G234S ENST00000337331 NM_153240.4 234 Ggc/Agc 0 +NPR1 UCSF GRCh37 1 153660173 153660173 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 80 184 0 ENST00000368680.3:c.2156C>T p.Ala719Val p.A719V ENST00000368680 NM_000906.3 719 gCt/gTt 0 +NR2F1 UCSF GRCh37 5 92923623 92923623 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 50 128 0 ENST00000327111.3:c.464C>T p.Ala155Val p.A155V ENST00000327111 NM_005654.4 155 gCg/gTg 0 +NR3C1 UCSF GRCh37 5 142779230 142779230 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 80 192 0 ENST00000231509.3:c.1175G>A p.Gly392Asp p.G392D ENST00000231509 392 gGc/gAc 0 +NR4A1 UCSF GRCh37 12 52449925 52449925 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 9 34 88 0 ENST00000360284.3:c.1027G>A p.Val343Met p.V343M ENST00000360284 NM_001202233.1 343 Gtg/Atg 0 +NR6A1 UCSF GRCh37 9 127302330 127302330 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 154 105 232 0 ENST00000487099.2:c.578G>A p.Gly193Asp p.G193D ENST00000487099 NM_001489.4 193 gGc/gAc 0 +NRF1 UCSF GRCh37 7 129330360 129330360 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 50 128 0 ENST00000393232.1:c.580C>T p.Pro194Ser p.P194S ENST00000393232 NM_005011.3 194 Cca/Tca 0 +NRM UCSF GRCh37 6 30656569 30656569 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 40 92 0 ENST00000259953.4:c.658C>T p.Leu220Phe p.L220F ENST00000259953 NM_007243.2 220 Ctt/Ttt 0 +NRP2 UCSF GRCh37 2 206608113 206608113 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 68 146 0 ENST00000360409.3:c.1478G>A p.Gly493Glu p.G493E ENST00000360409 NM_003872.2 493 gGa/gAa 0 +NRP2 UCSF GRCh37 2 206610533 206610533 + missense_variant Missense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 10 82 0 ENST00000360409.3:c.1705C>A p.Gln569Lys p.Q569K ENST00000360409 NM_003872.2 569 Cag/Aag 0 +NRSN2 UCSF GRCh37 20 334046 334046 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 45 112 0 ENST00000382291.3:c.382G>A p.Val128Ile p.V128I ENST00000382291 NM_024958.2 128 Gtt/Att 0 +NSRP1 UCSF GRCh37 17 28512333 28512333 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 71 129 0 ENST00000247026.5:c.1318C>T p.Arg440Ter p.R440* ENST00000247026 NM_032141.3 440 Cga/Tga 0 +NSUN2 UCSF GRCh37 5 6616964 6616964 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 69 158 0 ENST00000264670.6:c.897G>A p.Gln299= p.Q299= ENST00000264670 NM_017755.5 299 caG/caA 0 +NSUN4 UCSF GRCh37 1 46827324 46827324 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 116 217 0 ENST00000474844.1:c.961G>A p.Val321Met p.V321M ENST00000474844 NM_199044.3 321 Gtg/Atg 0 +NT5DC1 UCSF GRCh37 6 116542237 116542237 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 61 136 0 ENST00000319550.4:c.550C>T p.Pro184Ser p.P184S ENST00000319550 NM_152729.2 184 Cca/Tca 0 +NTF4 UCSF GRCh37 19 49564937 49564937 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 17 50 0 ENST00000301411.3:c.318C>T p.Asp106= p.D106= ENST00000301411 NM_006179.4 106 gaC/gaT 0 +NTN4 UCSF GRCh37 12 96180889 96180889 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 58 161 0 ENST00000343702.4:c.413G>A p.Arg138Lys p.R138K ENST00000343702 NM_021229.3 138 aGg/aAg 0 +NTN5 UCSF GRCh37 19 49173998 49173998 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 19 44 0 ENST00000270235.4:c.246C>T p.Phe82= p.F82= ENST00000270235 NM_145807.1 82 ttC/ttT 0 +NTNG1 UCSF GRCh37 1 107867358 107867358 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 64 150 0 ENST00000370068.1:c.701G>A p.Gly234Glu p.G234E ENST00000370068 234 gGa/gAa 0 +NUDC UCSF GRCh37 1 27268067 27268067 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 22 41 0 ENST00000321265.5:c.279G>A p.Lys93= p.K93= ENST00000321265 NM_006600.3 93 aaG/aaA 0 +NUP155 UCSF GRCh37 5 37338020 37338020 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 57 160 0 ENST00000231498.3:c.1247G>A p.Gly416Asp p.G416D ENST00000231498 NM_153485.2 416 gGt/gAt 0 +NUP210 UCSF GRCh37 3 13384708 13384708 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 57 106 0 ENST00000254508.5:c.2931C>T p.Asp977= p.D977= ENST00000254508 NM_024923.3 977 gaC/gaT 0 +NUP210L UCSF GRCh37 1 153974448 153974448 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 57 116 0 ENST00000368559.3:c.4944C>T p.Cys1648= p.C1648= ENST00000368559 NM_207308.2 1648 tgC/tgT 0 +NUP214 UCSF GRCh37 9 134108860 134108860 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 45 102 0 ENST00000359428.5:c.6259G>A p.Gly2087Ser p.G2087S ENST00000359428 NM_005085.3 2087 Ggc/Agc 0 +NUP54 UCSF GRCh37 4 77065364 77065364 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 187 172 336 0 ENST00000264883.3:c.233G>A p.Gly78Asp p.G78D ENST00000264883 NM_001278603.1 78 gGt/gAt 0 +NXF3 UCSF GRCh37 X 102335083 102335083 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 134 153 0 ENST00000395065.3:c.989C>T p.Thr330Ile p.T330I ENST00000395065 NM_022052.1 330 aCc/aTc 0 +OAS2 UCSF GRCh37 12 113446917 113446917 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 141 129 250 0 ENST00000342315.4:c.1921C>T p.Pro641Ser p.P641S ENST00000342315 NM_016817.2 641 Ccc/Tcc 0 +OASL UCSF GRCh37 12 121469348 121469348 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 64 153 0 ENST00000257570.5:c.554G>A p.Gly185Glu p.G185E ENST00000257570 NM_003733.3 185 gGa/gAa 0 +OBSCN UCSF GRCh37 1 228559629 228559629 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 33 61 0 ENST00000570156.2:c.24021C>T p.His8007= p.H8007= ENST00000570156 NM_001271223.2 8007 caC/caT 0 +OCRL UCSF GRCh37 X 128723821 128723821 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 79 87 0 ENST00000371113.4:c.2470-1G>A p.X824_splice ENST00000371113 NM_000276.3 0 +ODF2 UCSF GRCh37 9 131262385 131262385 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 76 187 0 ENST00000434106.3:c.2341G>A p.Asp781Asn p.D781N ENST00000434106 NM_153433.1 781 Gat/Aat 0 +ODF3L1 UCSF GRCh37 15 76019491 76019491 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 158 109 206 0 ENST00000332145.2:c.435C>T p.Tyr145= p.Y145= ENST00000332145 NM_175881.3 145 taC/taT 0 +ODF3L2 UCSF GRCh37 19 463984 463984 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 20 36 0 ENST00000315489.4:c.730T>A p.Cys244Ser p.C244S ENST00000315489 NM_182577.2 244 Tgc/Agc 0 +ODZ1 UCSF GRCh37 X 123518169 123518169 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 75 86 0 ENST00000422452.2:c.6612C>T p.Asp2204= p.D2204= ENST00000422452 NM_001163279.1 2204 gaC/gaT 0 +ODZ3 UCSF GRCh37 4 183676192 183676192 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 201 138 331 0 ENST00000511685.1:c.4672G>A p.Asp1558Asn p.D1558N ENST00000511685 1558 Gac/Aac 0 +ODZ4 UCSF GRCh37 11 78523317 78523317 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 22 60 0 ENST00000278550.7:c.1828G>A p.Gly610Ser p.G610S ENST00000278550 NM_001098816.2 610 Ggc/Agc 0 +OGFR UCSF GRCh37 20 61444910 61444910 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 32 85 0 ENST00000290291.6:c.1943G>A p.Gly648Glu p.G648E ENST00000290291 NM_007346.2 648 gGa/gAa 0 +OPLAH UCSF GRCh37 8 145114911 145114911 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 14 52 0 ENST00000426825.1:c.25C>T p.His9Tyr p.H9Y ENST00000426825 NM_017570.3 9 Cac/Tac 0 +OPRM1 UCSF GRCh37 6 154412611 154412611 + splice_region_variant,intron_variant Splice_Region SNP C C T snp132_rs79668187 P18_Rec Untested WXS Illumina HiSeq 68 45 107 0 ENST00000434900.2:c.1443+4C>T p.X481_splice ENST00000434900 NM_001145279.2 0 +OPTN UCSF GRCh37 10 13152332 13152332 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 67 152 0 ENST00000378748.3:c.225G>A p.Trp75Ter p.W75* ENST00000378748 NM_001008211.1 75 tgG/tgA 0 +OR10G3 UCSF GRCh37 14 22038246 22038246 + synonymous_variant Silent SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 125 94 195 0 ENST00000303532.1:c.630T>C p.Ser210= p.S210= ENST00000303532 NM_001005465.1 210 agT/agC 0 +OR10H4 UCSF GRCh37 19 16059991 16059991 + synonymous_variant Silent SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 247 156 320 0 ENST00000322107.1:c.174A>G p.Thr58= p.T58= ENST00000322107 NM_001004465.1 58 acA/acG 0 +OR13C5 UCSF GRCh37 9 107361276 107361276 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 151 121 267 0 ENST00000374779.2:c.419C>T p.Ala140Val p.A140V ENST00000374779 NM_001004482.1 140 gCc/gTc 0 +OR1E1 UCSF GRCh37 17 3301584 3301584 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 130 81 228 0 ENST00000322608.2:c.121G>A p.Gly41Arg p.G41R ENST00000322608 NM_003553.2 41 Ggg/Agg 0 +OR1K1 UCSF GRCh37 9 125563103 125563103 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 53 116 0 ENST00000277309.2:c.702G>A p.Gly234= p.G234= ENST00000277309 NM_080859.1 234 ggG/ggA 0 +OR2A7 UCSF GRCh37 7 143955843 143955843 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 379 76 777 0 ENST00000493325.1:c.879C>A p.Asn293Lys p.N293K ENST00000493325 NM_001005328.1 293 aaC/aaA 0 +OR2B3 UCSF GRCh37 6 29054995 29054995 + stop_gained Nonsense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 59 104 0 ENST00000377173.2:c.31G>T p.Glu11Ter p.E11* ENST00000377173 NM_001005226.2 11 Gag/Tag 0 +OR2G2 UCSF GRCh37 1 247752168 247752168 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 154 113 201 0 ENST00000320065.1:c.507G>A p.Leu169= p.L169= ENST00000320065 NM_001001915.1 169 ctG/ctA 0 +OR2G3 UCSF GRCh37 1 247769095 247769095 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 215 167 345 0 ENST00000320002.2:c.208G>A p.Asp70Asn p.D70N ENST00000320002 NM_001001914.1 70 Gac/Aac 0 +OR2M7 UCSF GRCh37 1 248487743 248487743 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 166 324 0 ENST00000317965.2:c.128C>T p.Ser43Phe p.S43F ENST00000317965 NM_001004691.1 43 tCc/tTc 0 +OR2T27 UCSF GRCh37 1 248813649 248813649 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 32 108 0 ENST00000344889.3:c.537C>T p.Cys179= p.C179= ENST00000344889 NM_001001824.1 179 tgC/tgT 0 +OR4F6 UCSF GRCh37 15 102346758 102346758 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 72 150 0 ENST00000328882.4:c.836C>T p.Thr279Ile p.T279I ENST00000328882 NM_001005326.1 279 aCt/aTt 0 +OR4S2 UCSF GRCh37 11 55418984 55418984 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 169 131 251 0 ENST00000312422.2:c.605G>A p.Gly202Asp p.G202D ENST00000312422 NM_001004059.2 202 gGt/gAt 0 +OR51F1 UCSF GRCh37 11 4790433 4790433 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 101 232 0 ENST00000343430.3:c.715G>A p.Val239Ile p.V239I ENST00000343430 NM_001004752.1 239 Gtc/Atc 0 +OR51I1 UCSF GRCh37 11 5462162 5462162 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 39 119 0 ENST00000380211.1:c.583C>T p.His195Tyr p.H195Y ENST00000380211 NM_001005288.2 195 Cat/Tat 0 +OR56B1 UCSF GRCh37 11 5758081 5758081 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 71 125 0 ENST00000317121.3:c.335C>T p.Ala112Val p.A112V ENST00000317121 NM_001005180.2 112 gCc/gTc 0 +OR5B17 UCSF GRCh37 11 58125703 58125703 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 97 221 0 ENST00000357377.3:c.840C>T p.Ile280= p.I280= ENST00000357377 NM_001005489.1 280 atC/atT 0 +OR5B3 UCSF GRCh37 11 58170526 58170526 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 106 248 0 ENST00000309403.2:c.357C>T p.Asp119= p.D119= ENST00000309403 NM_001005469.1 119 gaC/gaT 0 +OR5D14 UCSF GRCh37 11 55563678 55563678 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 185 110 252 0 ENST00000335605.1:c.647T>C p.Ile216Thr p.I216T ENST00000335605 NM_001004735.1 216 aTc/aCc 0 +OR5M10 UCSF GRCh37 11 56344312 56344312 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 230 161 343 0 ENST00000526812.2:c.886G>A p.Asp296Asn p.D296N ENST00000526812 NM_001004741.1 296 Gat/Aat 0 +OR5M9 UCSF GRCh37 11 56230263 56230263 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 58 126 0 ENST00000279791.1:c.615C>T p.Phe205= p.F205= ENST00000279791 NM_001004743.1 205 ttC/ttT 0 +OR6K2 UCSF GRCh37 1 158669593 158669593 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 73 161 0 ENST00000359610.2:c.850C>T p.Pro284Ser p.P284S ENST00000359610 NM_001005279.1 284 Ccc/Tcc 0 +OR6Y1 UCSF GRCh37 1 158517323 158517323 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 39 108 0 ENST00000302617.3:c.573C>T p.Asn191= p.N191= ENST00000302617 NM_001005189.1 191 aaC/aaT 0 +OR7G1 UCSF GRCh37 19 9226257 9226257 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 213 151 323 0 ENST00000541538.1:c.183C>T p.Phe61= p.F61= ENST00000541538 NM_001005192.2 61 ttC/ttT 0 +OR8G1 UCSF GRCh37 11 124120655 124120655 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 180 180 376 0 ENST00000341493.2:c.233C>T p.Thr78Ile p.T78I ENST00000341493 NM_001002905.1 78 aCc/aTc 0 +OR8G2 UCSF GRCh37 11 124095866 124095866 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 224 176 366 0 ENST00000366149.3:n.430C>T *144* ENST00000366149 0 +OR8G5 UCSF GRCh37 11 124135083 124135083 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 205 168 330 0 ENST00000524943.2:c.361G>A p.Val121Met p.V121M ENST00000524943 NM_001005198.1 121 Gtg/Atg 0 +ORC1 UCSF GRCh37 1 52859350 52859350 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 76 165 0 ENST00000371568.3:c.847C>T p.Leu283Phe p.L283F ENST00000371568 NM_001190818.1 283 Ctt/Ttt 0 +ORC1 UCSF GRCh37 1 52850228 52850228 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 72 154 0 ENST00000371568.3:c.1749C>T p.Ile583= p.I583= ENST00000371568 NM_001190818.1 583 atC/atT 0 +ORC4 UCSF GRCh37 2 148710093 148710093 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 51 176 0 ENST00000392857.5:c.437G>A p.Gly146Asp p.G146D ENST00000392857 NM_001190882.2 146 gGt/gAt 0 +ORMDL2 UCSF GRCh37 12 56212905 56212905 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 52 141 0 ENST00000243045.5:c.122C>T p.Pro41Leu p.P41L ENST00000243045 NM_014182.4 41 cCc/cTc 0 +OTOGL UCSF GRCh37 12 80665526 80665526 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 125 248 0 ENST00000458043.2:c.2590C>T p.Leu864= p.L864= ENST00000458043 NM_173591.3 864 Cta/Tta 0 +OTOL1 UCSF GRCh37 3 161220824 161220824 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 35 87 0 ENST00000327928.4:c.528C>T p.Gly176= p.G176= ENST00000327928 NM_001080440.1 176 ggC/ggT 0 +OTOR UCSF GRCh37 20 16730562 16730562 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 47 35 72 0 ENST00000246081.2:c.270C>T p.Gly90= p.G90= ENST00000246081 NM_020157.3 90 ggC/ggT 0 +OTUD6B UCSF GRCh37 8 92090594 92090594 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 32 95 0 ENST00000285420.4:c.416C>T p.Ala139Val p.A139V ENST00000285420 NM_016023.3 139 gCt/gTt 0 +OTUD7B UCSF GRCh37 1 149921614 149921614 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 53 106 0 ENST00000369135.4:c.1041C>T p.Arg347= p.R347= ENST00000369135 NM_020205.3 347 cgC/cgT 0 +OXCT1 UCSF GRCh37 5 41850167 41850167 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 45 122 0 ENST00000196371.5:c.529G>A p.Asp177Asn p.D177N ENST00000196371 NM_000436.3 177 Gat/Aat 0 +OXCT1 UCSF GRCh37 5 41803240 41803240 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 88 202 0 ENST00000196371.5:c.981C>T p.Leu327= p.L327= ENST00000196371 NM_000436.3 327 ctC/ctT 0 +OXCT1 UCSF GRCh37 5 41870383 41870383 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 20 53 0 ENST00000196371.5:c.78G>A p.Lys26= p.K26= ENST00000196371 NM_000436.3 26 aaG/aaA 0 +OXT UCSF GRCh37 20 3052734 3052734 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 8 8 0 ENST00000217386.2:c.132C>T p.Cys44= p.C44= ENST00000217386 NM_000915.3 44 tgC/tgT 0 +P2RX1 UCSF GRCh37 17 3808555 3808555 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 49 44 110 0 ENST00000225538.3:c.244C>T p.Pro82Ser p.P82S ENST00000225538 NM_002558.3 82 Ccc/Tcc 0 +P4HB UCSF GRCh37 17 79817154 79817154 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 64 161 0 ENST00000331483.4:c.255G>A p.Thr85= p.T85= ENST00000331483 NM_000918.3 85 acG/acA 0 +PACSIN1 UCSF GRCh37 6 34498080 34498080 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 30 29 51 0 ENST00000538621.1:c.849C>T p.Asp283= p.D283= ENST00000538621 NM_001199583.2 283 gaC/gaT 0 +PACSIN1 UCSF GRCh37 6 34496419 34496419 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 88 149 0 ENST00000538621.1:c.221G>A p.Gly74Asp p.G74D ENST00000538621 NM_001199583.2 74 gGc/gAc 0 +PADI4 UCSF GRCh37 1 17681089 17681089 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 67 134 0 ENST00000375448.4:c.1217C>T p.Ser406Phe p.S406F ENST00000375448 NM_012387.2 406 tCc/tTc 0 +PADI4 UCSF GRCh37 1 17668568 17668568 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 49 140 0 ENST00000375448.4:c.783C>T p.Phe261= p.F261= ENST00000375448 NM_012387.2 261 ttC/ttT 0 +PAF1 UCSF GRCh37 19 39880286 39880286 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 84 162 0 ENST00000221265.3:c.286C>T p.Pro96Ser p.P96S ENST00000221265 NM_019088.3 96 Ccc/Tcc 0 +PAFAH1B3 UCSF GRCh37 19 42804127 42804127 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 86 208 0 ENST00000538771.1:c.403G>A p.Val135Met p.V135M ENST00000538771 NM_001145940.1 135 Gtg/Atg 0 +PAK2 UCSF GRCh37 3 196509539 196509539 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 186 128 250 0 ENST00000327134.3:c.22G>A p.Glu8Lys p.E8K ENST00000327134 NM_002577.4 8 Gaa/Aaa 0 +PALLD UCSF GRCh37 4 169847516 169847516 + downstream_gene_variant 3'Flank SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 69 135 0 ENST00000505667 0 +PALLD UCSF GRCh37 4 169632805 169632805 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 62 143 0 ENST00000505667.1:c.1695C>T p.Pro565= p.P565= ENST00000505667 565 ccC/ccT 0 +PANK2 UCSF GRCh37 20 3891437 3891437 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 99 274 0 ENST00000316562.4:c.1195G>A p.Val399Ile p.V399I ENST00000316562 NM_153638.2 399 Gta/Ata 0 +PAPL UCSF GRCh37 19 39590972 39590972 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 113 88 198 0 ENST00000331256.5:c.611G>A p.Gly204Glu p.G204E ENST00000331256 NM_001004318.2 204 gGg/gAg 0 +PAPLN UCSF GRCh37 14 73727430 73727430 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 15 36 0 ENST00000340738.5:c.1918C>T p.Pro640Ser p.P640S ENST00000340738 NM_173462.3 640 Cct/Tct 0 +PAPOLB UCSF GRCh37 7 4900571 4900571 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 209 174 338 0 ENST00000404991.1:c.868C>T p.Pro290Ser p.P290S ENST00000404991 NM_020144.4 290 Cct/Tct 0 +PAPOLG UCSF GRCh37 2 60987413 60987413 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 82 156 0 ENST00000238714.3:c.162G>A p.Glu54= p.E54= ENST00000238714 NM_022894.3 54 gaG/gaA 0 +PAQR6 UCSF GRCh37 1 156213739 156213739 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 128 224 0 ENST00000335852.1:c.969G>A p.Glu323= p.E323= ENST00000335852 NM_024897.3 323 gaG/gaA 0 +PARD3B UCSF GRCh37 2 205990383 205990383 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 169 113 221 0 ENST00000358768.2:c.1356G>A p.Met452Ile p.M452I ENST00000358768 452 atG/atA 0 +PARD6A UCSF GRCh37 16 67695000 67695000 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 34 59 0 ENST00000219255.3:c.59G>A p.Ser20Asn p.S20N ENST00000219255 20 aGc/aAc 0 +PARD6A UCSF GRCh37 16 67696373 67696373 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 33 84 0 ENST00000219255.3:c.864G>A p.Glu288= p.E288= ENST00000219255 288 gaG/gaA 0 +PARP3 UCSF GRCh37 3 51978176 51978176 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 120 248 0 ENST00000398755.3:c.276C>T p.Ile92= p.I92= ENST00000398755 92 atC/atT 0 +PARVA UCSF GRCh37 11 12399244 12399244 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 5 14 26 0 ENST00000334956.8:c.170C>T p.Pro57Leu p.P57L ENST00000334956 NM_018222.4 57 cCc/cTc 0 +PATL1 UCSF GRCh37 11 59418277 59418277 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 34 115 0 ENST00000300146.9:c.1534G>A p.Glu512Lys p.E512K ENST00000300146 NM_152716.2 512 Gaa/Aaa 0 +PAX6 UCSF GRCh37 11 31815068 31815068 + missense_variant Missense_Mutation SNP C C T snp132_rs75572362 P18_Rec Untested WXS Illumina HiSeq 101 102 199 0 ENST00000419022.1:c.992G>A p.Arg331Gln p.R331Q ENST00000419022 NM_001258462.1 331 cGa/cAa 0 +PAX7 UCSF GRCh37 1 19062467 19062467 + synonymous_variant Silent SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 35 10 43 0 ENST00000375375.3:c.1497A>T p.Ser499= p.S499= ENST00000375375 NM_002584.2 499 tcA/tcT 0 +PAX8 UCSF GRCh37 2 114002114 114002114 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 174 112 265 0 ENST00000429538.3:c.279G>A p.Gly93= p.G93= ENST00000429538 NM_003466.3 93 ggG/ggA 0 +PBRM1 UCSF GRCh37 3 52702642 52702642 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 42 92 0 ENST00000394830.3:c.256G>A p.Glu86Lys p.E86K ENST00000394830 NM_018313.4 86 Gaa/Aaa 0 +PCBP2 UCSF GRCh37 12 53854828 53854828 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 79 142 0 ENST00000359462.5:c.405G>A p.Gly135= p.G135= ENST00000359462 135 ggG/ggA 0 +PCDH1 UCSF GRCh37 5 141248699 141248699 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 42 106 0 ENST00000287008.3:c.338C>T p.Thr113Ile p.T113I ENST00000287008 NM_032420.3 113 aCc/aTc 0 +PCDH12 UCSF GRCh37 5 141336753 141336753 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 75 141 0 ENST00000231484.3:c.664C>T p.Pro222Ser p.P222S ENST00000231484 NM_016580.3 222 Ccc/Tcc 0 +PCDH19 UCSF GRCh37 X 99661951 99661951 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 85 109 0 ENST00000373034.4:c.1645G>A p.Val549Met p.V549M ENST00000373034 NM_001184880.1 549 Gtg/Atg 0 +PCDHA5 UCSF GRCh37 5 140202528 140202528 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 127 93 217 0 ENST00000529859.1:c.1168C>T p.Pro390Ser p.P390S ENST00000529859 NM_018908.2 390 Ccc/Tcc 0 +PCDHB1 UCSF GRCh37 5 140432771 140432771 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 78 167 0 ENST00000306549.3:c.1716C>T p.Pro572= p.P572= ENST00000306549 NM_013340.2 572 ccC/ccT 0 +PCDHB16 UCSF GRCh37 5 140563139 140563139 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 134 77 177 0 ENST00000361016.2:c.1005G>A p.Leu335= p.L335= ENST00000361016 NM_020957.1 335 ctG/ctA 0 +PCDHB4 UCSF GRCh37 5 140503344 140503344 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 37 115 0 ENST00000194152.1:c.1764G>A p.Val588= p.V588= ENST00000194152 NM_018938.2 588 gtG/gtA 0 +PCDHB6 UCSF GRCh37 5 140531894 140531894 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 69 195 0 ENST00000231136.1:c.2056G>A p.Val686Ile p.V686I ENST00000231136 NM_018939.2 686 Gtc/Atc 0 +PCDHGA1 UCSF GRCh37 5 140711739 140711739 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 169 141 280 0 ENST00000517417.1:c.1488C>T p.Ile496= p.I496= ENST00000517417 NM_018912.2 496 atC/atT 0 +PCDHGA2 UCSF GRCh37 5 140719980 140719980 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 102 249 0 ENST00000394576.2:c.1442G>A p.Ser481Asn p.S481N ENST00000394576 NM_018915.2 481 aGc/aAc 0 +PCDHGA5 UCSF GRCh37 5 140744805 140744805 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 53 108 0 ENST00000518069.1:c.908C>T p.Thr303Ile p.T303I ENST00000518069 NM_018918.2 303 aCt/aTt 0 +PCDHGA8 UCSF GRCh37 5 140774817 140774817 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 178 120 246 0 ENST00000253812.6:c.2424+48793C>T *808* ENST00000253812 NM_018916.3 0 +PCDHGB1 UCSF GRCh37 5 140729999 140729999 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 46 112 0 ENST00000523390.1:c.172G>A p.Glu58Lys p.E58K ENST00000523390 NM_018922.2 58 Gag/Aag 0 +PCDHGB3 UCSF GRCh37 5 140751620 140751620 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 46 117 0 ENST00000576222.1:c.1659C>T p.Asp553= p.D553= ENST00000576222 NM_018924.2 553 gaC/gaT 0 +PCDHGB4 UCSF GRCh37 5 140768577 140768577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 83 212 0 ENST00000519479.1:c.1126C>T p.His376Tyr p.H376Y ENST00000519479 NM_003736.2 376 Cac/Tac 0 +PCDHGB6 UCSF GRCh37 5 140789820 140789820 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 74 202 0 ENST00000520790.1:c.2051C>T p.Pro684Leu p.P684L ENST00000520790 NM_018926.2 684 cCc/cTc 0 +PCDHGB7 UCSF GRCh37 5 140798542 140798542 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 155 116 272 0 ENST00000398594.2:c.1116G>A p.Arg372= p.R372= ENST00000398594 NM_018927.3 372 cgG/cgA 0 +PCDP1 UCSF GRCh37 2 120362768 120362768 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 53 130 0 ENST00000413369.3:c.1036G>A p.Gly346Ser p.G346S ENST00000413369 NM_001271049.1 346 Ggc/Agc 0 +PCF11 UCSF GRCh37 11 82875381 82875381 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 148 109 294 0 ENST00000298281.4:c.640C>T p.Gln214Ter p.Q214* ENST00000298281 NM_015885.3 214 Cag/Tag 0 +PCK2 UCSF GRCh37 14 24572399 24572399 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 24 51 0 ENST00000216780.4:c.1403G>A p.Trp468Ter p.W468* ENST00000216780 NM_004563.2 468 tGg/tAg 0 +PCK2 UCSF GRCh37 14 24572975 24572975 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 64 160 0 ENST00000216780.4:c.1725G>A p.Leu575= p.L575= ENST00000216780 NM_004563.2 575 ctG/ctA 0 +PCLO UCSF GRCh37 7 82583428 82583428 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 253 190 359 0 ENST00000333891.9:c.6841C>T p.Pro2281Ser p.P2281S ENST00000333891 NM_033026.5 2281 Cct/Tct 0 +PCLO UCSF GRCh37 7 82585868 82585868 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 254 159 408 0 ENST00000333891.9:c.4401G>A p.Glu1467= p.E1467= ENST00000333891 NM_033026.5 1467 gaG/gaA 0 +PCLO UCSF GRCh37 7 82579026 82579026 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 115 235 0 ENST00000333891.9:c.10878C>T p.Pro3626= p.P3626= ENST00000333891 NM_033026.5 3626 ccC/ccT 0 +PCNX UCSF GRCh37 14 71518672 71518672 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 97 200 0 ENST00000304743.2:c.4520G>A p.Ser1507Asn p.S1507N ENST00000304743 NM_014982.2 1507 aGt/aAt 0 +PCSK7 UCSF GRCh37 11 117079743 117079743 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 8 73 0 ENST00000320934.3:c.1561G>A p.Gly521Arg p.G521R ENST00000320934 NM_004716.2 521 Ggg/Agg 0 +PCSK7 UCSF GRCh37 11 117100424 117100424 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 26 30 65 0 ENST00000320934.3:c.137G>A p.Gly46Asp p.G46D ENST00000320934 NM_004716.2 46 gGc/gAc 0 +PCYOX1L UCSF GRCh37 5 148742296 148742296 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 111 78 188 0 ENST00000274569.4:c.185C>T p.Thr62Ile p.T62I ENST00000274569 NM_024028.3 62 aCc/aTc 0 +PDE1C UCSF GRCh37 7 31864559 31864559 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 175 112 274 0 ENST00000396193.1:c.1508C>T p.Thr503Met p.T503M ENST00000396193 NM_001191058.1 503 aCg/aTg 0 +PDE1C UCSF GRCh37 7 31887640 31887640 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 159 111 240 0 ENST00000396193.1:c.1102C>T p.Leu368Phe p.L368F ENST00000396193 NM_001191058.1 368 Ctt/Ttt 0 +PDE2A UCSF GRCh37 11 72293528 72293528 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 50 118 0 ENST00000334456.5:c.1811C>T p.Thr604Ile p.T604I ENST00000334456 NM_002599.4 604 aCc/aTc 0 +PDE4D UCSF GRCh37 5 59284412 59284412 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 191 147 266 0 ENST00000502484.2:c.175G>A p.Ala59Thr p.A59T ENST00000502484 NM_001165899.1 59 Gct/Act 0 +PDE4DIP UCSF GRCh37 1 144879476 144879476 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 300 83 330 0 ENST00000369356.4:c.3974G>A p.Ser1325Asn p.S1325N ENST00000369356 NM_014644.5 1325 aGt/aAt 0 +PDE5A UCSF GRCh37 4 120422325 120422325 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 56 138 0 ENST00000354960.3:c.2490G>A p.Glu830= p.E830= ENST00000354960 NM_001083.3 830 gaG/gaA 0 +PDE6B UCSF GRCh37 4 657647 657647 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 20 20 29 0 ENST00000496514.1:c.2009C>T p.Ala670Val p.A670V ENST00000496514 670 gCc/gTc 0 +PDE6C UCSF GRCh37 10 95385407 95385407 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 53 85 0 ENST00000371447.3:c.939+1G>A p.X313_splice ENST00000371447 NM_006204.3 0 +PDE8A UCSF GRCh37 15 85664105 85664105 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 96 163 0 ENST00000310298.4:c.1812C>T p.Thr604= p.T604= ENST00000310298 604 acC/acT 0 +PDGFA UCSF GRCh37 7 551993 551993 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 20 63 0 ENST00000354513.5:c.260G>A p.Ser87Asn p.S87N ENST00000354513 NM_002607.5 87 aGc/aAc 0 +PDLIM3 UCSF GRCh37 4 186429600 186429600 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 79 168 0 ENST00000284770.5:c.515C>T p.Pro172Leu p.P172L ENST00000284770 NM_014476.5 172 cCt/cTt 0 +PDLIM7 UCSF GRCh37 5 176911158 176911158 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 50 118 0 ENST00000355841.2:c.1084G>A p.Val362Met p.V362M ENST00000355841 NM_005451.4 362 Gtg/Atg 0 +PDLIM7 UCSF GRCh37 5 176915113 176915113 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 75 134 0 ENST00000355841.2:c.1006C>T p.Arg336Cys p.R336C ENST00000355841 NM_005451.4 336 Cgc/Tgc 0 +PDZD2 UCSF GRCh37 5 32087729 32087729 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 40 100 0 ENST00000438447.1:c.4175C>T p.Ala1392Val p.A1392V ENST00000438447 1392 gCc/gTc 0 +PDZD2 UCSF GRCh37 5 31995702 31995702 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 54 141 0 ENST00000438447.1:c.999G>A p.Trp333Ter p.W333* ENST00000438447 333 tgG/tgA 0 +PEG3 UCSF GRCh37 19 57327800 57327800 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 155 106 227 0 ENST00000326441.9:c.2010G>A p.Gln670= p.Q670= ENST00000326441 NM_006210.2 670 caG/caA 0 +PELO UCSF GRCh37 5 52096954 52096954 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 71 142 0 ENST00000274311.2:c.726G>A p.Gln242= p.Q242= ENST00000274311 NM_015946.4 242 caG/caA 0 +PET112 UCSF GRCh37 4 152637283 152637283 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 57 43 110 0 ENST00000263985.6:c.641G>A p.Gly214Glu p.G214E ENST00000263985 NM_004564.2 214 gGa/gAa 0 +PEX13 UCSF GRCh37 2 61272904 61272904 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 71 168 0 ENST00000295030.5:c.831C>T p.Ala277= p.A277= ENST00000295030 NM_002618.3 277 gcC/gcT 0 +PEX14 UCSF GRCh37 1 10684432 10684432 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 66 127 0 ENST00000356607.4:c.523G>A p.Glu175Lys p.E175K ENST00000356607 NM_004565.2 175 Gag/Aag 0 +PEX5L UCSF GRCh37 3 179597794 179597794 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 68 141 0 ENST00000467460.1:c.428G>A p.Gly143Glu p.G143E ENST00000467460 NM_001256751.1 143 gGa/gAa 0 +PEX6 UCSF GRCh37 6 42936056 42936056 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 22 60 0 ENST00000304611.8:c.1660C>T p.Leu554Phe p.L554F ENST00000304611 NM_000287.3 554 Ctc/Ttc 0 +PFKM UCSF GRCh37 12 48536631 48536631 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 75 142 0 ENST00000340802.6:c.1933G>A p.Gly645Ser p.G645S ENST00000340802 NM_001166686.1 645 Ggt/Agt 0 +PGLS UCSF GRCh37 19 17628524 17628528 + frameshift_variant Frame_Shift_Del DEL GGAGA GGAGA - NOVEL P18_Rec Untested WXS Illumina HiSeq 49 0 ENST00000252603.2:c.504_508del p.Glu169AspfsTer7 p.E169Dfs*7 ENST00000252603 NM_012088.2 168 cgGGAGAag/cgag 0 +PGM3 UCSF GRCh37 6 83900605 83900605 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 82 191 0 ENST00000506587.1:c.211G>A p.Gly71Arg p.G71R ENST00000506587 NM_001199917.1 71 Gga/Aga 0 +PGR UCSF GRCh37 11 100933464 100933464 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 54 140 0 ENST00000325455.5:c.1926C>T p.Phe642= p.F642= ENST00000325455 NM_001202474.3 642 ttC/ttT 0 +PHF12 UCSF GRCh37 17 27233392 27233392 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 47 121 0 ENST00000332830.4:c.2824G>A p.Glu942Lys p.E942K ENST00000332830 NM_001033561.1 942 Gag/Aag 0 +PHF14 UCSF GRCh37 7 11022578 11022578 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 134 254 0 ENST00000403050.3:c.692G>A p.Gly231Glu p.G231E ENST00000403050 NM_014660.3 231 gGa/gAa 0 +PHF17 UCSF GRCh37 4 129783248 129783248 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 53 169 0 ENST00000226319.6:c.1371G>A p.Lys457= p.K457= ENST00000226319 NM_199320.2 457 aaG/aaA 0 +PHF6 UCSF GRCh37 X 133547969 133547969 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 106 126 0 ENST00000332070.3:c.702G>A p.Lys234= p.K234= ENST00000332070 NM_032458.2 234 aaG/aaA 0 +PHIP UCSF GRCh37 6 79650787 79650787 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 128 259 0 ENST00000275034.4:c.5089G>A p.Glu1697Lys p.E1697K ENST00000275034 NM_017934.5 1697 Gaa/Aaa 0 +PHKB UCSF GRCh37 16 47533749 47533749 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 131 114 245 0 ENST00000323584.5:c.249G>A p.Lys83= p.K83= ENST00000323584 NM_000293.2 83 aaG/aaA 0 +PHKG2 UCSF GRCh37 16 30767589 30767589 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 105 86 187 0 ENST00000563588.1:c.643G>A p.Asp215Asn p.D215N ENST00000563588 NM_000294.2 215 Gac/Aac 0 +PHOX2B UCSF GRCh37 4 41750393 41750393 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 29 102 0 ENST00000226382.2:c.235G>A p.Ala79Thr p.A79T ENST00000226382 NM_003924.3 79 Gcc/Acc 0 +PHRF1 UCSF GRCh37 11 606577 606577 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 22 65 0 ENST00000416188.2:c.1587C>T p.Ser529= p.S529= ENST00000416188 529 tcC/tcT 0 +PHTF2 UCSF GRCh37 7 77549735 77549735 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 200 130 300 0 ENST00000416283.2:c.814G>A p.Glu272Lys p.E272K ENST00000416283 NM_020432.4 272 Gaa/Aaa 0 +PHYHD1 UCSF GRCh37 9 131696310 131696310 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 59 108 0 ENST00000308941.5:c.289G>A p.Glu97Lys p.E97K ENST00000308941 NM_174933.3 97 Gag/Aag 0 +PI4K2B UCSF GRCh37 4 25270136 25270136 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 58 115 0 ENST00000264864.6:c.1150C>T p.Pro384Ser p.P384S ENST00000264864 NM_018323.3 384 Cca/Tca 0 +PIAS1 UCSF GRCh37 15 68473593 68473593 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 186 147 297 0 ENST00000249636.6:c.1525C>T p.Pro509Ser p.P509S ENST00000249636 NM_016166.1 509 Cca/Tca 0 +PIDD UCSF GRCh37 11 799413 799413 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 53 112 0 ENST00000347755.5:c.2627G>A p.Gly876Asp p.G876D ENST00000347755 NM_145886.3 876 gGc/gAc 0 +PIEZO2 UCSF GRCh37 18 10680198 10680198 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 59 143 0 ENST00000503781.3:c.7611G>A p.Gln2537= p.Q2537= ENST00000503781 NM_022068.2 2537 caG/caA 0 +PIGL UCSF GRCh37 17 16221183 16221183 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 68 145 0 ENST00000225609.5:c.621C>T p.Val207= p.V207= ENST00000225609 NM_004278.3 207 gtC/gtT 0 +PIGO UCSF GRCh37 9 35095060 35095060 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 61 145 0 ENST00000378617.3:c.503C>T p.Thr168Ile p.T168I ENST00000378617 NM_032634.3 168 aCc/aTc 0 +PIGW UCSF GRCh37 17 34892953 34892953 + start_lost Translation_Start_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 54 148 0 ENST00000592983.1:c.3G>A p.Met1? p.M1? ENST00000592983 1 atG/atA 0 +PIK3CA UCSF GRCh37 3 178936082 178936082 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 76 58 158 0 ENST00000263967.3:c.1624G>A p.Glu542Lys p.E542K ENST00000263967 NM_006218.2 542 Gaa/Aaa 0 +PIK3CA UCSF GRCh37 3 178936076 178936076 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 70 57 153 0 ENST00000263967.3:c.1618C>G p.Leu540Val p.L540V ENST00000263967 NM_006218.2 540 Ctc/Gtc 0 +PIK3CD UCSF GRCh37 1 9775947 9775947 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 22 58 0 ENST00000377346.4:c.411C>T p.Asn137= p.N137= ENST00000377346 NM_005026.3 137 aaC/aaT 0 +PIK3R3 UCSF GRCh37 1 46532727 46532727 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 206 140 288 0 ENST00000262741.5:c.351C>T p.His117= p.H117= ENST00000262741 NM_003629.3 117 caC/caT 0 +PIK3R5 UCSF GRCh37 17 8791876 8791876 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 22 44 0 ENST00000447110.1:c.1228G>A p.Glu410Lys p.E410K ENST00000447110 NM_001251855.1 410 Gaa/Aaa 0 +PIKFYVE UCSF GRCh37 2 209214753 209214753 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 85 197 1 ENST00000264380.4:c.5380G>A p.Val1794Ile p.V1794I ENST00000264380 NM_015040.3 1794 Gta/Ata 0 +PILRB UCSF GRCh37 7 99956627 99956627 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 73 195 0 ENST00000610247.1:c.379G>A p.Val127Ile p.V127I ENST00000610247 127 Gtc/Atc 0 +PINX1 UCSF GRCh37 8 10623210 10623210 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 161 110 230 0 ENST00000314787.3:c.688C>T p.Pro230Ser p.P230S ENST00000314787 NM_017884.4 230 Cct/Tct 0 +PIP5KL1 UCSF GRCh37 9 130688199 130688199 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 34 77 0 ENST00000388747.4:c.710C>T p.Pro237Leu p.P237L ENST00000388747 NM_001135219.1 237 cCc/cTc 0 +PIWIL4 UCSF GRCh37 11 94341853 94341853 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 106 177 0 ENST00000299001.6:c.1943+1G>A p.X648_splice ENST00000299001 NM_152431.2 0 +PKD1 UCSF GRCh37 16 2160943 2160943 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 152 39 99 0 ENST00000262304.4:c.4225C>T p.Pro1409Ser p.P1409S ENST00000262304 NM_001009944.2 1409 Ccc/Tcc 0 +PKD1 UCSF GRCh37 16 2164604 2164604 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 8 16 0 ENST00000262304.4:c.2420C>T p.Ser807Phe p.S807F ENST00000262304 NM_001009944.2 807 tCc/tTc 0 +PKD1 UCSF GRCh37 16 2149911 2149911 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 34 69 0 ENST00000262304.4:c.9874C>T p.Leu3292= p.L3292= ENST00000262304 NM_001009944.2 3292 Ctg/Ttg 0 +PKD1 UCSF GRCh37 16 2159333 2159333 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 43 39 0 ENST00000262304.4:c.5835C>T p.Asp1945= p.D1945= ENST00000262304 NM_001009944.2 1945 gaC/gaT 0 +PKD2L1 UCSF GRCh37 10 102051073 102051073 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 64 191 0 ENST00000318222.3:c.1992C>T p.Asp664= p.D664= ENST00000318222 NM_016112.2 664 gaC/gaT 0 +PKHD1 UCSF GRCh37 6 51612952 51612952 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 219 170 363 0 ENST00000371117.3:c.9462C>T p.Asp3154= p.D3154= ENST00000371117 NM_138694.3 3154 gaC/gaT 0 +PLA2R1 UCSF GRCh37 2 160832690 160832690 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 47 115 0 ENST00000283243.7:c.2484C>T p.Thr828= p.T828= ENST00000283243 NM_001195641.1 828 acC/acT 0 +PLAGL1 UCSF GRCh37 6 144263210 144263210 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 69 152 0 ENST00000360537.2:c.743C>T p.Ala248Val p.A248V ENST00000360537 248 gCc/gTc 0 +PLAU UCSF GRCh37 10 75673360 75673360 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 180 138 301 0 ENST00000372764.3:c.524C>T p.Pro175Leu p.P175L ENST00000372764 NM_002658.3 175 cCc/cTc 0 +PLAUR UCSF GRCh37 19 44169538 44169538 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 68 155 0 ENST00000340093.3:c.240G>A p.Arg80= p.R80= ENST00000340093 NM_002659.3 80 cgG/cgA 0 +PLCB3 UCSF GRCh37 11 64030184 64030184 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 55 151 0 ENST00000540288.1:c.2259C>T p.Gly753= p.G753= ENST00000540288 NM_000932.2 753 ggC/ggT 0 +PLCD1 UCSF GRCh37 3 38050863 38050863 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 53 133 0 ENST00000463876.1:c.1569C>T p.Val523= p.V523= ENST00000463876 NM_001130964.1 523 gtC/gtT 0 +PLCH1 UCSF GRCh37 3 155301352 155301352 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 100 197 0 ENST00000340059.7:c.644G>A p.Arg215Gln p.R215Q ENST00000340059 NM_001130960.1 215 cGa/cAa 0 +PLCL1 UCSF GRCh37 2 198950615 198950615 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 132 93 200 0 ENST00000428675.1:c.2374G>A p.Ala792Thr p.A792T ENST00000428675 NM_006226.3 792 Gcc/Acc 0 +PLCL1 UCSF GRCh37 2 198949378 198949378 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 170 121 257 0 ENST00000428675.1:c.1137G>A p.Gln379= p.Q379= ENST00000428675 NM_006226.3 379 caG/caA 0 +PLEC UCSF GRCh37 8 145007028 145007028 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 12 35 0 ENST00000322810.4:c.2081G>A p.Ser694Asn p.S694N ENST00000322810 NM_201380.2 694 aGc/aAc 0 +PLEC UCSF GRCh37 8 145010156 145010156 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 37 73 0 ENST00000322810.4:c.873G>A p.Gln291= p.Q291= ENST00000322810 NM_201380.2 291 caG/caA 0 +PLEC UCSF GRCh37 8 144992720 144992720 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 35 16 41 0 ENST00000322810.4:c.11680C>T p.Leu3894= p.L3894= ENST00000322810 NM_201380.2 3894 Ctg/Ttg 0 +PLEKHA6 UCSF GRCh37 1 204197900 204197900 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 59 113 0 ENST00000272203.3:c.2841G>A p.Lys947= p.K947= ENST00000272203 NM_014935.4 947 aaG/aaA 0 +PLEKHA6 UCSF GRCh37 1 204198137 204198137 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 41 89 0 ENST00000272203.3:c.2679C>T p.Pro893= p.P893= ENST00000272203 NM_014935.4 893 ccC/ccT 0 +PLEKHD1 UCSF GRCh37 14 69995020 69995020 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 15 9 31 0 ENST00000322564.7:c.1405G>A p.Glu469Lys p.E469K ENST00000322564 NM_001161498.1 469 Gag/Aag 0 +PLEKHG1 UCSF GRCh37 6 151130280 151130280 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 60 144 0 ENST00000367328.1:c.952C>T p.Leu318= p.L318= ENST00000367328 NM_001029884.1 318 Ctg/Ttg 0 +PLEKHG6 UCSF GRCh37 12 6427914 6427914 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 30 88 0 ENST00000396988.3:c.1279G>A p.Asp427Asn p.D427N ENST00000396988 NM_001144856.1 427 Gac/Aac 0 +PLEKHM2 UCSF GRCh37 1 16051828 16051828 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 6 26 0 ENST00000375799.3:c.729C>T p.Asp243= p.D243= ENST00000375799 NM_015164.2 243 gaC/gaT 0 +PLIN2 UCSF GRCh37 9 19121023 19121023 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 30 114 242 0 ENST00000276914.2:c.450G>A p.Glu150= p.E150= ENST00000276914 NM_001122.3 150 gaG/gaA 0 +PLIN4 UCSF GRCh37 19 4512632 4512632 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 195 145 329 0 ENST00000301286.3:c.1298C>T p.Ala433Val p.A433V ENST00000301286 NM_001080400.1 433 gCc/gTc 0 +PLK3 UCSF GRCh37 1 45270338 45270338 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 93 235 0 ENST00000372201.4:c.1522C>T p.Pro508Ser p.P508S ENST00000372201 NM_004073.2 508 Ccc/Tcc 0 +PLP2 UCSF GRCh37 X 49029528 49029528 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 41 60 0 ENST00000376327.5:c.149C>T p.Ser50Phe p.S50F ENST00000376327 NM_002668.2 50 tCc/tTc 0 +PLS1 UCSF GRCh37 3 142430816 142430816 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 186 155 291 0 ENST00000337777.3:c.1857C>T p.Cys619= p.C619= ENST00000337777 NM_002670.2 619 tgC/tgT 0 +PLSCR3 UCSF GRCh37 17 7296785 7296785 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 157 151 269 0 ENST00000535512.1:c.286+1G>A p.X96_splice ENST00000535512 0 +PLSCR4 UCSF GRCh37 3 145924492 145924492 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 34 62 0 ENST00000354952.2:c.175G>A p.Gly59Arg p.G59R ENST00000354952 NM_020353.2 59 Gga/Aga 0 +PLXDC2 UCSF GRCh37 10 20432236 20432236 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 303 94 230 0 ENST00000377252.4:c.554C>T p.Thr185Ile p.T185I ENST00000377252 NM_032812.7 185 aCt/aTt 0 +PLXNA2 UCSF GRCh37 1 208218062 208218062 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 17 64 0 ENST00000367033.3:c.3665C>T p.Ser1222Leu p.S1222L ENST00000367033 NM_025179.3 1222 tCg/tTg 0 +PLXNA2 UCSF GRCh37 1 208272261 208272261 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 26 58 0 ENST00000367033.3:c.1661C>T p.Ala554Val p.A554V ENST00000367033 NM_025179.3 554 gCc/gTc 0 +PLXNA2 UCSF GRCh37 1 208227865 208227865 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 51 77 0 ENST00000367033.3:c.2757C>T p.Gly919= p.G919= ENST00000367033 NM_025179.3 919 ggC/ggT 0 +PLXNB1 UCSF GRCh37 3 48462134 48462134 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 16 59 0 ENST00000358536.4:c.1968G>A p.Trp656Ter p.W656* ENST00000358536 NM_002673.4 656 tgG/tgA 0 +PLXND1 UCSF GRCh37 3 129290040 129290040 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 55 48 126 0 ENST00000324093.4:c.3443A>G p.Asp1148Gly p.D1148G ENST00000324093 NM_015103.2 1148 gAc/gGc 0 +PML UCSF GRCh37 15 74325727 74325727 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 37 75 0 ENST00000268058.3:c.1629C>T p.Asn543= p.N543= ENST00000268058 NM_033238.2 543 aaC/aaT 0 +PMM1 UCSF GRCh37 22 41973821 41973821 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 55 139 0 ENST00000216259.7:c.657G>A p.Glu219= p.E219= ENST00000216259 NM_002676.2 219 gaG/gaA 0 +PNLIPRP3 UCSF GRCh37 10 118220511 118220511 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 125 69 189 0 ENST00000369230.3:c.599C>T p.Thr200Ile p.T200I ENST00000369230 NM_001011709.2 200 aCt/aTt 0 +POC1A UCSF GRCh37 3 52109984 52109984 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 76 171 0 ENST00000296484.2:c.1143G>A p.Glu381= p.E381= ENST00000296484 NM_015426.4 381 gaG/gaA 0 +POGK UCSF GRCh37 1 166810316 166810316 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 59 137 0 ENST00000367875.1:c.123G>A p.Glu41= p.E41= ENST00000367875 41 gaG/gaA 0 +POGZ UCSF GRCh37 1 151396657 151396657 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 108 184 0 ENST00000271715.2:c.1291C>T p.Pro431Ser p.P431S ENST00000271715 NM_015100.3 431 Cct/Tct 0 +POLA1 UCSF GRCh37 X 25014013 25014013 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 75 73 0 ENST00000379059.3:c.4335C>T p.Gly1445= p.G1445= ENST00000379059 NM_016937.3 1445 ggC/ggT 0 +POLD1 UCSF GRCh37 19 50905276 50905276 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 32 85 0 ENST00000440232.2:c.484G>T p.Gly162Cys p.G162C ENST00000440232 NM_002691.3 162 Ggt/Tgt 0 +POLDIP3 UCSF GRCh37 22 42988024 42988024 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 104 224 0 ENST00000252115.5:c.958G>A p.Val320Met p.V320M ENST00000252115 NM_001278657.1 320 Gtg/Atg 0 +POLH UCSF GRCh37 6 43582155 43582155 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 235 152 309 0 ENST00000372236.4:c.2003C>T p.Ser668Phe p.S668F ENST00000372236 NM_006502.2 668 tCt/tTt 0 +POLN UCSF GRCh37 4 2129915 2129915 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 203 141 308 1 ENST00000511885.2:c.1907C>T p.Ser636Phe p.S636F ENST00000511885 636 tCt/tTt 0 +POLN UCSF GRCh37 4 2159619 2159619 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 145 117 251 0 ENST00000511885.2:c.1631C>T p.Thr544Ile p.T544I ENST00000511885 544 aCc/aTc 0 +POLR1E UCSF GRCh37 9 37503132 37503132 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 65 166 0 ENST00000377798.4:c.1193C>T p.Thr398Ile p.T398I ENST00000377798 NM_022490.1 398 aCc/aTc 0 +POLR1E UCSF GRCh37 9 37486787 37486787 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 104 224 0 ENST00000377798.4:c.164G>A p.Arg55Lys p.R55K ENST00000377798 NM_022490.1 55 aGg/aAg 0 +POLR3A UCSF GRCh37 10 79745098 79745098 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 93 91 145 0 ENST00000372371.3:c.3072G>A p.Arg1024= p.R1024= ENST00000372371 NM_007055.3 1024 agG/agA 0 +POM121 UCSF GRCh37 7 72400590 72400590 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 190 141 339 0 ENST00000395270.1:c.421C>T p.Pro141Ser p.P141S ENST00000395270 NM_001257190.2 141 Cct/Tct 0 +POMZP3 UCSF GRCh37 7 76240803 76240803 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 100 149 0 ENST00000310842.4:c.543G>A p.Trp181Ter p.W181* ENST00000310842 NM_012230.3 181 tgG/tgA 0 +POU2F3 UCSF GRCh37 11 120139950 120139950 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 64 120 0 ENST00000260264.4:c.135G>A p.Arg45= p.R45= ENST00000260264 NM_001244682.1 45 agG/agA 0 +POU3F1 UCSF GRCh37 1 38511573 38511573 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 44 91 0 ENST00000373012.2:c.843C>T p.Gly281= p.G281= ENST00000373012 NM_002699.3 281 ggC/ggT 0 +PPAPDC3 UCSF GRCh37 9 134165721 134165721 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 49 108 0 ENST00000372264.3:c.337G>A p.Val113Ile p.V113I ENST00000372264 NM_032728.3 113 Gtc/Atc 0 +PPARGC1A UCSF GRCh37 4 23826108 23826108 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 151 310 0 ENST00000264867.2:c.781C>T p.Pro261Ser p.P261S ENST00000264867 NM_013261.3 261 Cct/Tct 0 +PPARGC1B UCSF GRCh37 5 149214929 149214929 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 78 163 0 ENST00000309241.5:c.1807+1G>A p.X603_splice ENST00000309241 NM_133263.3 0 +PPEF2 UCSF GRCh37 4 76797592 76797592 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 42 26 79 0 ENST00000286719.7:c.1168G>A p.Val390Met p.V390M ENST00000286719 NM_006239.2 390 Gtg/Atg 0 +PPFIA1 UCSF GRCh37 11 70201767 70201767 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 81 141 0 ENST00000253925.7:c.2338C>T p.Pro780Ser p.P780S ENST00000253925 NM_003626.3 780 Ccc/Tcc 0 +PPIG UCSF GRCh37 2 170493450 170493450 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 94 197 0 ENST00000260970.3:c.1682G>A p.Arg561Lys p.R561K ENST00000260970 NM_004792.2 561 aGa/aAa 0 +PPIP5K1 UCSF GRCh37 15 43827298 43827298 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 103 209 0 ENST00000420765.1:c.3876C>T p.Asn1292= p.N1292= ENST00000420765 NM_001130858.2 1292 aaC/aaT 0 +PPL UCSF GRCh37 16 4953973 4953973 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 21 64 0 ENST00000345988.2:c.231C>T p.Asp77= p.D77= ENST00000345988 NM_002705.4 77 gaC/gaT 0 +PPP1R13B UCSF GRCh37 14 104219354 104219354 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 62 141 0 ENST00000202556.9:c.811C>T p.Leu271= p.L271= ENST00000202556 NM_015316.2 271 Ctg/Ttg 0 +PPP1R15A UCSF GRCh37 19 49376632 49376632 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 29 62 0 ENST00000200453.5:c.142G>A p.Glu48Lys p.E48K ENST00000200453 NM_014330.3 48 Gaa/Aaa 0 +PPP1R16A UCSF GRCh37 8 145722709 145722709 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 23 49 0 ENST00000292539.4:c.132C>T p.Ala44= p.A44= ENST00000292539 44 gcC/gcT 0 +PPP1R3D UCSF GRCh37 20 58514666 58514666 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 27 6 20 0 ENST00000370996.3:c.321C>T p.Asp107= p.D107= ENST00000370996 NM_006242.3 107 gaC/gaT 0 +PPP2R5C UCSF GRCh37 14 102368190 102368190 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 57 153 0 ENST00000422945.2:c.1080G>A p.Arg360= p.R360= ENST00000422945 NM_001161725.1 360 cgG/cgA 0 +PPP3CB UCSF GRCh37 10 75230479 75230479 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 64 136 0 ENST00000394829.2:c.948G>A p.Ser316= p.S316= ENST00000394829 NM_001142353.1 316 tcG/tcA 0 +PPP3CC UCSF GRCh37 8 22368658 22368658 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 135 96 200 0 ENST00000397775.3:c.544C>T p.Pro182Ser p.P182S ENST00000397775 NM_001243974.1 182 Cct/Tct 0 +PPP6R2 UCSF GRCh37 22 50869666 50869666 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 58 188 0 ENST00000395741.3:c.1193C>T p.Ala398Val p.A398V ENST00000395741 398 gCt/gTt 0 +PPT1 UCSF GRCh37 1 40544268 40544268 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 66 177 0 ENST00000433473.3:c.690C>T p.Phe230= p.F230= ENST00000433473 NM_000310.3 230 ttC/ttT 0 +PRAMEF1 UCSF GRCh37 1 12854201 12854201 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 351 176 605 0 ENST00000332296.7:c.425G>A p.Gly142Glu p.G142E ENST00000332296 NM_023013.2 142 gGa/gAa 0 +PRAMEF12 UCSF GRCh37 1 12836049 12836049 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 156 114 239 0 ENST00000357726.4:c.651C>T p.Ser217= p.S217= ENST00000357726 NM_001080830.1 217 tcC/tcT 0 +PRAMEF4 UCSF GRCh37 1 12941966 12941966 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 105 301 0 ENST00000235349.5:c.584G>A p.Arg195His p.R195H ENST00000235349 NM_001009611.2 195 cGc/cAc 0 +PRAMEF6 UCSF GRCh37 1 13001251 13001251 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 420 108 732 0 ENST00000376189.1:c.432G>A p.Gln144= p.Q144= ENST00000376189 NM_001010889.2 144 caG/caA 0 +PRAMEF7 UCSF GRCh37 1 12979697 12979697 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 45 235 0 ENST00000361079.2:c.889G>A p.Val297Ile p.V297I ENST00000361079 297 Gtc/Atc 0 +PRB4 UCSF GRCh37 12 11461546 11461546 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 214 69 289 0 ENST00000279575.1:c.371C>T p.Pro124Leu p.P124L ENST00000279575 NM_001261399.1 124 cCc/cTc 0 +PRDM10 UCSF GRCh37 11 129814713 129814713 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 114 85 190 0 ENST00000358825.5:c.715C>T p.Pro239Ser p.P239S ENST00000358825 NM_020228.2 239 Cct/Tct 0 +PRDM15 UCSF GRCh37 21 43221771 43221771 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 65 38 104 0 ENST00000269844.3:c.4153C>T p.Leu1385Phe p.L1385F ENST00000269844 NM_022115.3 1385 Ctc/Ttc 0 +PRDM15 UCSF GRCh37 21 43258105 43258105 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 76 202 0 ENST00000269844.3:c.2037G>A p.Arg679= p.R679= ENST00000269844 NM_022115.3 679 cgG/cgA 0 +PRDM16 UCSF GRCh37 1 3334421 3334421 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 97 177 0 ENST00000270722.5:c.2721G>A p.Lys907= p.K907= ENST00000270722 907 aaG/aaA 0 +PRDM2 UCSF GRCh37 1 14106287 14106287 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 70 148 0 ENST00000235372.7:c.1997G>A p.Ser666Asn p.S666N ENST00000235372 NM_012231.4 666 aGt/aAt 0 +PRDM2 UCSF GRCh37 1 14106776 14106776 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 80 180 0 ENST00000235372.7:c.2486G>A p.Gly829Asp p.G829D ENST00000235372 NM_012231.4 829 gGt/gAt 0 +PRDM4 UCSF GRCh37 12 108147759 108147759 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 47 98 0 ENST00000228437.5:c.273C>T p.Thr91= p.T91= ENST00000228437 NM_012406.3 91 acC/acT 0 +PRDX2 UCSF GRCh37 19 12911811 12911811 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 33 72 0 ENST00000301522.2:c.176G>A p.Ser59Asn p.S59N ENST00000301522 NM_005809.5 59 aGc/aAc 0 +PREX2 UCSF GRCh37 8 69017553 69017553 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 61 151 0 ENST00000288368.4:c.2716-2791C>T *906* ENST00000288368 NM_024870.2 0 +PRG4 UCSF GRCh37 1 186276020 186276020 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 63 126 0 ENST00000445192.2:c.1169C>T p.Pro390Leu p.P390L ENST00000445192 NM_005807.3 390 cCc/cTc 0 +PRIC285 UCSF GRCh37 20 62191299 62191299 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 25 56 0 ENST00000467148.1:c.7807G>A p.Glu2603Lys p.E2603K ENST00000467148 NM_001037335.2 2603 Gag/Aag 0 +PRIM2 UCSF GRCh37 6 57398214 57398214 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 428 114 714 1 ENST00000607273.1:c.917G>A p.Arg306Gln p.R306Q ENST00000607273 NM_000947.3 306 cGa/cAa 0 +PRKACG UCSF GRCh37 9 71628387 71628387 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 43 110 0 ENST00000377276.2:c.622C>T p.Pro208Ser p.P208S ENST00000377276 NM_002732.3 208 Ccc/Tcc 0 +PRKAG2 UCSF GRCh37 7 151573591 151573591 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 28 49 1 ENST00000287878.4:c.114+1G>A p.X38_splice ENST00000287878 NM_016203.3 0 +PRKCH UCSF GRCh37 14 61857951 61857951 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0014 P18_Rec Untested WXS Illumina HiSeq 75 67 130 0 ENST00000332981.5:c.372C>T p.Leu124= p.L124= ENST00000332981 NM_006255.3 124 ctC/ctT 0 +PRKCSH UCSF GRCh37 19 11552127 11552127 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 67 217 0 ENST00000252455.2:c.423G>A p.Lys141= p.K141= ENST00000252455 NM_002743.2 141 aaG/aaA 0 +PRKD1 UCSF GRCh37 14 30100122 30100122 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 90 179 0 ENST00000331968.5:c.1498G>A p.Val500Met p.V500M ENST00000331968 NM_002742.2 500 Gtg/Atg 0 +PRKD2 UCSF GRCh37 19 47195006 47195006 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 72 150 0 ENST00000433867.1:c.1688G>A p.Gly563Glu p.G563E ENST00000433867 NM_001079881.1 563 gGa/gAa 0 +PRKD2 UCSF GRCh37 19 47204305 47204305 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 55 83 0 ENST00000433867.1:c.954C>T p.Ala318= p.A318= ENST00000433867 NM_001079881.1 318 gcC/gcT 0 +PRMT10 UCSF GRCh37 4 148604985 148604985 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 41 108 0 ENST00000322396.6:c.154C>T p.Leu52Phe p.L52F ENST00000322396 NM_138364.2 52 Ctc/Ttc 0 +PRMT6 UCSF GRCh37 1 107600343 107600343 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 29 83 1 ENST00000370078.1:c.1006G>A p.Asp336Asn p.D336N ENST00000370078 336 Gac/Aac 0 +PRMT7 UCSF GRCh37 16 68380067 68380067 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 71 159 0 ENST00000339507.5:c.1075G>A p.Val359Ile p.V359I ENST00000339507 359 Gtc/Atc 0 +PROKR2 UCSF GRCh37 20 5294982 5294982 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 61 130 0 ENST00000546004.1:c.34C>T p.Pro12Ser p.P12S ENST00000546004 12 Ccc/Tcc 0 +PROL1 UCSF GRCh37 4 71275570 71275570 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 71 194 0 ENST00000399575.2:c.525C>T p.Ile175= p.I175= ENST00000399575 NM_021225.4 175 atC/atT 0 +PROM2 UCSF GRCh37 2 95941741 95941741 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 16 29 0 ENST00000317620.9:c.358G>A p.Val120Met p.V120M ENST00000317620 NM_001165978.1 120 Gtg/Atg 0 +PRPF19 UCSF GRCh37 11 60665699 60665699 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 60 137 0 ENST00000227524.4:c.1185C>T p.Ile395= p.I395= ENST00000227524 NM_014502.4 395 atC/atT 0 +PRPF31 UCSF GRCh37 19 54634839 54634839 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 48 99 0 ENST00000321030.4:c.1476G>A p.Glu492= p.E492= ENST00000321030 NM_015629.3 492 gaG/gaA 0 +PRPH2 UCSF GRCh37 6 42689649 42689649 + missense_variant Missense_Mutation SNP G G A snp132_rs61755783 P18_Rec Untested WXS Illumina HiSeq 83 89 162 0 ENST00000230381.5:c.424C>T p.Arg142Trp p.R142W ENST00000230381 NM_000322.4 142 Cgg/Tgg 0 +PRR13 UCSF GRCh37 12 53837352 53837352 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 7 25 90 0 ENST00000429243.2:c.197C>T p.Pro66Leu p.P66L ENST00000429243 NM_018457.3 66 cCa/cTa 0 +PRR14 UCSF GRCh37 16 30664424 30664424 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 42 85 0 ENST00000542965.2:c.504G>A p.Glu168= p.E168= ENST00000542965 168 gaG/gaA 0 +PRR14L UCSF GRCh37 22 32111480 32111480 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 129 308 0 ENST00000327423.6:c.2345C>T p.Ser782Phe p.S782F ENST00000327423 NM_173566.2 782 tCt/tTt 0 +PRR3 UCSF GRCh37 6 30529888 30529888 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 73 205 0 ENST00000376560.3:c.447C>T p.Pro149= p.P149= ENST00000376560 NM_025263.3 149 ccC/ccT 0 +PRRC2A UCSF GRCh37 6 31599022 31599022 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 102 73 164 0 ENST00000376033.2:c.2572G>A p.Glu858Lys p.E858K ENST00000376033 NM_004638.3 858 Gaa/Aaa 0 +PRRC2B UCSF GRCh37 9 134350096 134350096 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 62 141 0 ENST00000357304.4:c.2580C>T p.Val860= p.V860= ENST00000357304 NM_013318.3 860 gtC/gtT 0 +PRRC2B UCSF GRCh37 9 134362554 134362554 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 45 95 0 ENST00000357304.4:c.5857G>A p.Ala1953Thr p.A1953T ENST00000357304 NM_013318.3 1953 Gcc/Acc 0 +PRRC2C UCSF GRCh37 1 171519286 171519286 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 147 114 237 0 ENST00000338920.4:c.5028G>A p.Leu1676= p.L1676= ENST00000338920 NM_015172.3 1676 ttG/ttA 0 +PRRT2 UCSF GRCh37 16 29824379 29824379 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 44 91 0 ENST00000567659.1:c.4G>A p.Ala2Thr p.A2T ENST00000567659 2 Gca/Aca 0 +PRSS1 UCSF GRCh37 7 142460858 142460858 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 173 107 209 0 ENST00000311737.7:c.731C>T p.Ala244Val p.A244V ENST00000311737 NM_002769.4 244 gCt/gTt 0 +PRSS21 UCSF GRCh37 16 2871579 2871579 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 50 106 0 ENST00000005995.3:c.918G>A p.Trp306Ter p.W306* ENST00000005995 306 tgG/tgA 0 +PRSS27 UCSF GRCh37 16 2763685 2763685 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 27 92 0 ENST00000302641.3:c.523C>T p.Pro175Ser p.P175S ENST00000302641 NM_031948.3 175 Ccg/Tcg 0 +PRSS36 UCSF GRCh37 16 31160803 31160803 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 34 105 1 ENST00000268281.4:c.90G>A p.Gln30= p.Q30= ENST00000268281 NM_173502.4 30 caG/caA 0 +PRSS48 UCSF GRCh37 4 152203454 152203454 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 180 327 0 ENST00000455694.2:c.370G>A p.Val124Ile p.V124I ENST00000455694 NM_183375.2 124 Gtc/Atc 0 +PSAP UCSF GRCh37 10 73594165 73594165 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 42 69 0 ENST00000394936.3:c.138G>A p.Lys46= p.K46= ENST00000394936 46 aaG/aaA 0 +PSAP UCSF GRCh37 10 73579249 73579249 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 48 143 0 ENST00000394936.3:c.1323C>T p.Ser441= p.S441= ENST00000394936 441 agC/agT 0 +PSD2 UCSF GRCh37 5 139219697 139219697 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 54 122 0 ENST00000274710.3:c.2054G>A p.Gly685Asp p.G685D ENST00000274710 NM_032289.2 685 gGc/gAc 0 +PSD3 UCSF GRCh37 8 18413857 18413857 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 113 242 0 ENST00000327040.8:c.2790G>A p.Glu930= p.E930= ENST00000327040 NM_015310.3 930 gaG/gaA 0 +PSD4 UCSF GRCh37 2 113953307 113953307 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 59 160 0 ENST00000245796.6:c.2185C>T p.Leu729Phe p.L729F ENST00000245796 NM_012455.2 729 Ctc/Ttc 0 +PSEN1 UCSF GRCh37 14 73683941 73683941 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 95 169 0 ENST00000324501.5:c.1237G>A p.Ala413Thr p.A413T ENST00000324501 NM_000021.3 413 Gcc/Acc 0 +PSMB1 UCSF GRCh37 6 170858151 170858151 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 61 108 0 ENST00000262193.6:c.164C>T p.Thr55Ile p.T55I ENST00000262193 NM_002793.3 55 aCt/aTt 0 +PSMB8 UCSF GRCh37 6 32809339 32809339 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 144 101 213 0 ENST00000374882.3:c.711C>T p.His237= p.H237= ENST00000374882 NM_148919.3 237 caC/caT 0 +PSMC1 UCSF GRCh37 14 90725515 90725515 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 43 118 0 ENST00000261303.8:c.15G>A p.Gln5= p.Q5= ENST00000261303 NM_002802.2 5 caG/caA 0 +PTBP1 UCSF GRCh37 19 806408 806408 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 21 19 0 ENST00000356948.6:c.971G>A p.Gly324Asp p.G324D ENST00000356948 NM_002819.4 324 gGc/gAc 0 +PTCHD1 UCSF GRCh37 X 23410906 23410906 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 143 151 1 ENST00000379361.4:c.1271G>A p.Ser424Asn p.S424N ENST00000379361 NM_173495.2 424 aGc/aAc 0 +PTCHD2 UCSF GRCh37 1 11579791 11579791 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 67 139 0 ENST00000294484.6:c.2054G>A p.Gly685Glu p.G685E ENST00000294484 NM_020780.1 685 gGa/gAa 0 +PTCRA UCSF GRCh37 6 42890938 42890938 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 70 155 0 ENST00000304672.1:c.232C>T p.Pro78Ser p.P78S ENST00000304672 NM_001243168.1 78 Cct/Tct 0 +PTDSS2 UCSF GRCh37 11 489641 489641 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 5 9 26 0 ENST00000308020.5:c.1023C>T p.Pro341= p.P341= ENST00000308020 NM_030783.1 341 ccC/ccT 0 +PTGS2 UCSF GRCh37 1 186647536 186647536 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 42 145 0 ENST00000367468.5:c.314C>T p.Ser105Phe p.S105F ENST00000367468 NM_000963.2 105 tCc/tTc 0 +PTPN12 UCSF GRCh37 7 77247874 77247874 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 129 106 226 0 ENST00000248594.6:c.1017G>A p.Arg339= p.R339= ENST00000248594 NM_002835.3 339 agG/agA 0 +PTPN13 UCSF GRCh37 4 87706518 87706518 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 77 57 115 0 ENST00000436978.1:c.6268C>T p.Pro2090Ser p.P2090S ENST00000436978 NM_080685.2 2090 Cca/Tca 0 +PTPN13 UCSF GRCh37 4 87732259 87732259 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 76 53 115 0 ENST00000436978.1:c.7375G>A p.Glu2459Lys p.E2459K ENST00000436978 NM_080685.2 2459 Gag/Aag 0 +PTPN14 UCSF GRCh37 1 214557113 214557113 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 42 39 94 0 ENST00000366956.5:c.2085G>A p.Lys695= p.K695= ENST00000366956 NM_005401.4 695 aaG/aaA 0 +PTPN23 UCSF GRCh37 3 47449443 47449443 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 19 47 0 ENST00000265562.4:c.1182G>A p.Leu394= p.L394= ENST00000265562 NM_015466.2 394 ctG/ctA 0 +PTPRA UCSF GRCh37 20 2968684 2968684 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 147 121 265 0 ENST00000380393.3:c.534G>A p.Lys178= p.K178= ENST00000380393 NM_002836.3 178 aaG/aaA 0 +PTPRD UCSF GRCh37 9 8518354 8518354 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 97 147 0 ENST00000356435.5:c.1037G>A p.Gly346Glu p.G346E ENST00000356435 346 gGg/gAg 0 +PTPRK UCSF GRCh37 6 128302298 128302298 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 44 104 0 ENST00000368213.5:c.3692G>A p.Gly1231Glu p.G1231E ENST00000368213 NM_001135648.1 1231 gGg/gAg 0 +PTPRM UCSF GRCh37 18 7955142 7955142 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 45 149 0 ENST00000580170.1:c.862C>T p.Pro288Ser p.P288S ENST00000580170 NM_001105244.1 288 Cct/Tct 0 +PTPRN UCSF GRCh37 2 220155002 220155002 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 23 55 0 ENST00000295718.2:c.2886C>T p.Ala962= p.A962= ENST00000295718 NM_002846.3 962 gcC/gcT 0 +PTPRT UCSF GRCh37 20 40790034 40790034 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 61 145 0 ENST00000373198.4:c.2697G>A p.Gln899= p.Q899= ENST00000373198 NM_133170.3 899 caG/caA 0 +PTPRZ1 UCSF GRCh37 7 121653306 121653306 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 105 234 0 ENST00000393386.2:c.4206G>A p.Leu1402= p.L1402= ENST00000393386 NM_001206838.1 1402 ctG/ctA 0 +PUF60 UCSF GRCh37 8 144898928 144898928 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 104 180 0 ENST00000526683.1:c.1442G>A p.Gly481Glu p.G481E ENST00000526683 NM_001271098.1 481 gGg/gAg 0 +PVRL3 UCSF GRCh37 3 110830999 110830999 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 75 191 0 ENST00000485303.1:c.283C>T p.His95Tyr p.H95Y ENST00000485303 NM_001243286.1 95 Cat/Tat 0 +PWP2 UCSF GRCh37 21 45542135 45542135 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 80 160 0 ENST00000291576.7:c.1714C>T p.Pro572Ser p.P572S ENST00000291576 NM_005049.2 572 Cct/Tct 0 +PWP2 UCSF GRCh37 21 45535238 45535238 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 86 189 0 ENST00000291576.7:c.564G>A p.Lys188= p.K188= ENST00000291576 NM_005049.2 188 aaG/aaA 0 +PXDN UCSF GRCh37 2 1670193 1670193 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 6 25 55 0 ENST00000252804.4:c.1084G>A p.Glu362Lys p.E362K ENST00000252804 NM_012293.1 362 Gag/Aag 0 +PYGM UCSF GRCh37 11 64514753 64514753 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 38 126 0 ENST00000164139.3:c.2255C>T p.Ser752Phe p.S752F ENST00000164139 NM_005609.2 752 tCc/tTc 0 +PYHIN1 UCSF GRCh37 1 158906715 158906715 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 65 133 0 ENST00000368140.1:c.15C>T p.Tyr5= p.Y5= ENST00000368140 NM_152501.4 5 taC/taT 0 +PYHIN1 UCSF GRCh37 1 158946491 158946491 + splice_region_variant,3_prime_UTR_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 140 80 198 0 ENST00000368140.1:c.*6G>A p.X2_splice ENST00000368140 NM_152501.4 0 +PYROXD2 UCSF GRCh37 10 100143560 100143560 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 131 93 201 0 ENST00000370575.4:c.1741A>G p.Met581Val p.M581V ENST00000370575 NM_032709.2 581 Atg/Gtg 0 +RAB11FIP5 UCSF GRCh37 2 73316440 73316440 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 97 184 0 ENST00000258098.6:c.435G>A p.Trp145Ter p.W145* ENST00000258098 NM_015470.2 145 tgG/tgA 0 +RAB18 UCSF GRCh37 10 27821451 27821451 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 315 128 219 0 ENST00000356940.6:c.202G>A p.Glu68Lys p.E68K ENST00000356940 NM_001256410.1 68 Gag/Aag 0 +RAB19 UCSF GRCh37 7 140125911 140125911 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 52 132 0 ENST00000537763.1:c.615G>A p.Met205Ile p.M205I ENST00000537763 NM_001008749.2 205 atG/atA 0 +RAB20 UCSF GRCh37 13 111176438 111176438 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 52 128 0 ENST00000267328.3:c.279C>T p.Asp93= p.D93= ENST00000267328 NM_017817.1 93 gaC/gaT 0 +RAB26 UCSF GRCh37 16 2198927 2198927 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 7 15 11 0 ENST00000210187.6:c.143C>T p.Pro48Leu p.P48L ENST00000210187 NM_014353.4 48 cCc/cTc 0 +RAB3D UCSF GRCh37 19 11446138 11446138 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 35 62 0 ENST00000222120.3:c.457C>T p.Leu153Phe p.L153F ENST00000222120 NM_004283.3 153 Ctc/Ttc 0 +RAB40AL UCSF GRCh37 X 102192759 102192759 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 49 77 0 ENST00000218249.5:c.513C>T p.Ala171= p.A171= ENST00000218249 NM_001031834.1 171 gcC/gcT 0 +RAD1 UCSF GRCh37 5 34908987 34908987 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 113 245 0 ENST00000382038.2:c.732G>A p.Arg244= p.R244= ENST00000382038 NM_002853.3 244 cgG/cgA 0 +RAD18 UCSF GRCh37 3 8940731 8940731 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 193 56 105 0 ENST00000264926.2:c.1169G>A p.Gly390Glu p.G390E ENST00000264926 NM_020165.3 390 gGa/gAa 0 +RAD9B UCSF GRCh37 12 110960024 110960024 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 98 217 0 ENST00000392672.4:c.933C>T p.Gly311= p.G311= ENST00000392672 NM_152442.3 311 ggC/ggT 0 +RAET1E UCSF GRCh37 6 150210512 150210512 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 55 128 0 ENST00000357183.4:c.594G>A p.Gly198= p.G198= ENST00000357183 NM_139165.2 198 ggG/ggA 0 +RAI1 UCSF GRCh37 17 17697865 17697865 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 59 52 94 0 ENST00000353383.1:c.1603G>A p.Ala535Thr p.A535T ENST00000353383 NM_030665.3 535 Gcc/Acc 0 +RALA UCSF GRCh37 7 39726287 39726287 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 64 158 0 ENST00000005257.2:c.21G>A p.Lys7= p.K7= ENST00000005257 NM_005402.3 7 aaG/aaA 0 +RANBP17 UCSF GRCh37 5 170640635 170640635 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 132 76 151 0 ENST00000523189.1:c.2232G>A p.Met744Ile p.M744I ENST00000523189 NM_022897.3 744 atG/atA 0 +RANBP2 UCSF GRCh37 2 109398766 109398766 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 130 115 253 0 ENST00000283195.6:c.8943G>A p.Val2981= p.V2981= ENST00000283195 NM_006267.4 2981 gtG/gtA 0 +RANBP2 UCSF GRCh37 2 109392223 109392223 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 84 221 0 ENST00000283195.6:c.8328C>T p.Asp2776= p.D2776= ENST00000283195 NM_006267.4 2776 gaC/gaT 0 +RANBP2 UCSF GRCh37 2 109382380 109382380 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 132 90 216 0 ENST00000283195.6:c.5385G>A p.Glu1795= p.E1795= ENST00000283195 NM_006267.4 1795 gaG/gaA 0 +RAP1GAP2 UCSF GRCh37 17 2901517 2901517 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 193 123 291 0 ENST00000254695.8:c.1047C>T p.Leu349= p.L349= ENST00000254695 NM_015085.4 349 ctC/ctT 0 +RAP1GDS1 UCSF GRCh37 4 99264359 99264359 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 113 106 177 1 ENST00000339360.5:c.185A>C p.Gln62Pro p.Q62P ENST00000339360 62 cAg/cCg 0 +RAPGEF1 UCSF GRCh37 9 134463203 134463203 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 52 104 0 ENST00000372190.3:c.2649G>A p.Leu883= p.L883= ENST00000372190 NM_198679.1 883 ttG/ttA 0 +RAPGEF2 UCSF GRCh37 4 160277170 160277170 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 20 62 0 ENST00000264431.4:c.4334C>T p.Ala1445Val p.A1445V ENST00000264431 NM_014247.2 1445 gCt/gTt 0 +RAPH1 UCSF GRCh37 2 204304764 204304764 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 56 118 0 ENST00000319170.5:c.3149C>T p.Ala1050Val p.A1050V ENST00000319170 NM_213589.1 1050 gCc/gTc 0 +RAPH1 UCSF GRCh37 2 204306084 204306084 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 17 23 0 ENST00000319170.5:c.1829C>T p.Ser610Phe p.S610F ENST00000319170 NM_213589.1 610 tCc/tTc 0 +RASAL1 UCSF GRCh37 12 113573235 113573235 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 14 16 16 0 ENST00000546530.1:c.33G>A p.Val11= p.V11= ENST00000546530 NM_004658.2 11 gtG/gtA 0 +RAVER2 UCSF GRCh37 1 65278515 65278515 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 60 117 0 ENST00000371072.4:c.1736C>T p.Pro579Leu p.P579L ENST00000371072 NM_018211.3 579 cCc/cTc 0 +RBCK1 UCSF GRCh37 20 390563 390563 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 82 208 0 ENST00000356286.5:c.61G>A p.Gly21Ser p.G21S ENST00000356286 NM_031229.2 21 Ggc/Agc 0 +RBFOX1 UCSF GRCh37 16 7568257 7568257 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 208 92 195 0 ENST00000311745.5:c.196C>T p.Pro66Ser p.P66S ENST00000311745 NM_145891.2 66 Ccc/Tcc 0 +RBM12 UCSF GRCh37 20 34241744 34241744 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 200 141 280 0 ENST00000374114.3:c.1501C>T p.Gln501Ter p.Q501* ENST00000374114 NM_001198838.1 501 Caa/Taa 0 +RBM14 UCSF GRCh37 11 66392770 66392770 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 126 103 192 0 ENST00000310137.4:c.1423G>A p.Gly475Arg p.G475R ENST00000310137 NM_006328.3 475 Ggg/Agg 0 +RBM15 UCSF GRCh37 1 110883854 110883854 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 49 38 67 0 ENST00000369784.3:c.1827G>A p.Glu609= p.E609= ENST00000369784 NM_022768.4 609 gaG/gaA 0 +RBM19 UCSF GRCh37 12 114377894 114377894 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 56 153 0 ENST00000545145.2:c.1809G>A p.Leu603= p.L603= ENST00000545145 NM_001146699.1 603 ctG/ctA 0 +RBM26 UCSF GRCh37 13 79932554 79932554 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 36 115 0 ENST00000267229.7:c.1544G>A p.Arg515Lys p.R515K ENST00000267229 NM_022118.3 515 aGa/aAa 0 +RBMS2 UCSF GRCh37 12 56975264 56975264 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 25 54 113 0 ENST00000262031.5:c.704G>A p.Gly235Glu p.G235E ENST00000262031 NM_002898.3 235 gGa/gAa 0 +RBP3 UCSF GRCh37 10 48388215 48388215 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 26 71 0 ENST00000224600.4:c.2663C>T p.Pro888Leu p.P888L ENST00000224600 NM_002900.2 888 cCc/cTc 0 +RBPJL UCSF GRCh37 20 43942178 43942178 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 22 44 0 ENST00000343694.3:c.690C>T p.Tyr230= p.Y230= ENST00000343694 NM_001281449.1 230 taC/taT 0 +RCOR1 UCSF GRCh37 14 103188554 103188554 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 78 186 0 ENST00000262241.6:c.1220C>T p.Ala407Val p.A407V ENST00000262241 NM_015156.3 407 gCa/gTa 0 +RDX UCSF GRCh37 11 110124675 110124675 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 65 142 0 ENST00000405097.1:c.955G>A p.Glu319Lys p.E319K ENST00000405097 NM_001260492.1 319 Gaa/Aaa 0 +RECK UCSF GRCh37 9 36112353 36112353 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 61 112 0 ENST00000377966.3:c.1940G>A p.Gly647Glu p.G647E ENST00000377966 NM_021111.2 647 gGg/gAg 0 +RECK UCSF GRCh37 9 36118754 36118754 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 42 84 0 ENST00000377966.3:c.2254C>T p.Pro752Ser p.P752S ENST00000377966 NM_021111.2 752 Ccc/Tcc 0 +REEP1 UCSF GRCh37 2 86444230 86444230 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 44 95 0 ENST00000538924.1:c.620C>T p.Thr207Ile p.T207I ENST00000538924 NM_001164730.1 207 aCc/aTc 0 +REEP5 UCSF GRCh37 5 112257851 112257851 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 13 38 0 ENST00000379638.4:c.37C>T p.Leu13= p.L13= ENST00000379638 NM_005669.4 13 Ctg/Ttg 0 +RELB UCSF GRCh37 19 45537734 45537734 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 18 63 0 ENST00000221452.8:c.1302G>A p.Arg434= p.R434= ENST00000221452 NM_006509.3 434 cgG/cgA 0 +REM2 UCSF GRCh37 14 23354170 23354170 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 51 87 0 ENST00000267396.4:c.391G>A p.Ala131Thr p.A131T ENST00000267396 NM_173527.2 131 Gca/Aca 0 +REV3L UCSF GRCh37 6 111694354 111694354 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 154 121 213 0 ENST00000358835.3:c.5204G>A p.Ser1735Asn p.S1735N ENST00000358835 1735 aGc/aAc 0 +REV3L UCSF GRCh37 6 111678216 111678216 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 83 208 0 ENST00000358835.3:c.7184+1G>A p.X2395_splice ENST00000358835 0 +RFPL2 UCSF GRCh37 22 32588955 32588955 + missense_variant Missense_Mutation SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 99 212 0 ENST00000400237.1:c.490A>T p.Ile164Phe p.I164F ENST00000400237 164 Atc/Ttc 0 +RGNEF UCSF GRCh37 5 73072480 73072480 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 233 141 367 0 ENST00000545377.1:c.799C>T p.Leu267Phe p.L267F ENST00000545377 NM_001080479.2 267 Ctc/Ttc 0 +RGS10 UCSF GRCh37 10 121285617 121285617 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P18_Rec Untested WXS Illumina HiSeq 30 0 ENST00000369103.2:c.182del p.Lys61ArgfsTer12 p.K61Rfs*12 ENST00000369103 NM_001005339.1 61 aAg/ag 0 +RGS20 UCSF GRCh37 8 54791981 54791981 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 38 94 0 ENST00000297313.3:c.329C>T p.Ala110Val p.A110V ENST00000297313 NM_170587.2 110 gCc/gTc 0 +RGS22 UCSF GRCh37 8 101076176 101076176 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 153 105 244 0 ENST00000360863.6:c.820G>A p.Glu274Lys p.E274K ENST00000360863 NM_015668.3 274 Gaa/Aaa 0 +RHBDF2 UCSF GRCh37 17 74469187 74469187 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 35 61 0 ENST00000313080.4:c.1897G>A p.Val633Met p.V633M ENST00000313080 NM_024599.5 633 Gtg/Atg 0 +RHCE UCSF GRCh37 1 25715505 25715505 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 51 140 0 ENST00000294413.7:c.901G>A p.Ala301Thr p.A301T ENST00000294413 NM_020485.4 301 Gct/Act 0 +RHOBTB1 UCSF GRCh37 10 62670645 62670645 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 43 112 0 ENST00000337910.5:c.296G>A p.Arg99Lys p.R99K ENST00000337910 NM_001242359.1 99 aGg/aAg 0 +RHOBTB2 UCSF GRCh37 8 22868171 22868171 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 101 198 0 ENST00000519685.1:c.1807C>T p.Leu603Phe p.L603F ENST00000519685 NM_001160036.1 603 Ctc/Ttc 0 +RHPN1 UCSF GRCh37 8 144462236 144462236 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 15 28 0 ENST00000289013.6:c.1107G>A p.Ala369= p.A369= ENST00000289013 NM_052924.2 369 gcG/gcA 0 +RIMS1 UCSF GRCh37 6 72892596 72892596 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 11 14 0 ENST00000521978.1:c.1422C>T p.Ser474= p.S474= ENST00000521978 NM_014989.5 474 agC/agT 0 +RIN2 UCSF GRCh37 20 19970700 19970700 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 46 112 0 ENST00000255006.6:c.1960G>A p.Gly654Arg p.G654R ENST00000255006 NM_018993.3 654 Ggg/Agg 0 +RIN2 UCSF GRCh37 20 19945668 19945668 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 173 130 267 0 ENST00000255006.6:c.683G>A p.Arg228Lys p.R228K ENST00000255006 NM_018993.3 228 aGg/aAg 0 +RING1 UCSF GRCh37 6 33179242 33179242 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 8 24 0 ENST00000374656.4:c.763C>T p.Pro255Ser p.P255S ENST00000374656 NM_002931.3 255 Ccc/Tcc 0 +RIPK4 UCSF GRCh37 21 43161833 43161833 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 64 47 118 0 ENST00000332512.3:c.1520C>T p.Ala507Val p.A507V ENST00000332512 NM_020639.2 507 gCc/gTc 0 +RIPK4 UCSF GRCh37 21 43171318 43171318 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 68 129 0 ENST00000332512.3:c.562C>T p.Leu188Phe p.L188F ENST00000332512 NM_020639.2 188 Ctc/Ttc 0 +RLF UCSF GRCh37 1 40688383 40688383 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 69 180 0 ENST00000372771.4:c.947+1G>A p.X316_splice ENST00000372771 NM_012421.3 0 +RLN3 UCSF GRCh37 19 14141712 14141712 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 43 157 0 ENST00000431365.2:c.381C>T p.Ser127= p.S127= ENST00000431365 NM_080864.2 127 agC/agT 0 +RLTPR UCSF GRCh37 16 67690536 67690536 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 29 64 0 ENST00000334583.6:c.4024C>T p.Pro1342Ser p.P1342S ENST00000334583 NM_001013838.1 1342 Ccc/Tcc 0 +RNF123 UCSF GRCh37 3 49750002 49750002 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 56 121 0 ENST00000327697.6:c.2587C>T p.Pro863Ser p.P863S ENST00000327697 NM_022064.3 863 Ccc/Tcc 0 +RNF168 UCSF GRCh37 3 196229968 196229968 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 57 129 0 ENST00000318037.3:c.77C>T p.Pro26Leu p.P26L ENST00000318037 NM_152617.3 26 cCc/cTc 0 +RNF208 UCSF GRCh37 9 140114906 140114906 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 8 12 0 ENST00000392827.1:c.759C>T p.Asn253= p.N253= ENST00000392827 253 aaC/aaT 0 +RNF25 UCSF GRCh37 2 219528704 219528704 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 72 150 0 ENST00000295704.2:c.1356C>T p.Gly452= p.G452= ENST00000295704 NM_022453.2 452 ggC/ggT 0 +RNF32 UCSF GRCh37 7 156437244 156437244 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 63 101 0 ENST00000405335.1:c.67G>A p.Asp23Asn p.D23N ENST00000405335 23 Gat/Aat 0 +RP1L1 UCSF GRCh37 8 10468205 10468205 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 69 174 0 ENST00000382483.3:c.3403C>T p.Pro1135Ser p.P1135S ENST00000382483 NM_178857.5 1135 Cct/Tct 0 +RPL21 UCSF GRCh37 13 27830577 27830577 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 51 117 0 ENST00000311549.6:c.398C>T p.Ala133Val p.A133V ENST00000311549 NM_000982.3 133 gCt/gTt 0 +RPL22L1 UCSF GRCh37 3 170584270 170584270 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 83 61 141 0 ENST00000295830.8:c.268C>T p.Leu90Phe p.L90F ENST00000295830 NM_001099645.1 90 Ctt/Ttt 0 +RPL5 UCSF GRCh37 1 93300406 93300406 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 200 133 278 0 ENST00000370321.3:c.260G>A p.Gly87Asp p.G87D ENST00000370321 NM_000969.3 87 gGt/gAt 0 +RPL5 UCSF GRCh37 1 93301773 93301773 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 160 99 254 0 ENST00000370321.3:c.351G>A p.Lys117= p.K117= ENST00000370321 NM_000969.3 117 aaG/aaA 0 +RPL8 UCSF GRCh37 8 146017481 146017481 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 11 37 0 ENST00000262584.3:c.34G>A p.Ala12Thr p.A12T ENST00000262584 NM_000973.3 12 Gcc/Acc 0 +RPLP0 UCSF GRCh37 12 120637204 120637204 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 62 142 0 ENST00000551150.1:c.139C>T p.Leu47Phe p.L47F ENST00000551150 47 Ctt/Ttt 0 +RPP38 UCSF GRCh37 10 15145394 15145394 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 238 92 190 0 ENST00000378197.4:c.81C>T p.Asn27= p.N27= ENST00000378197 NM_183005.4 27 aaC/aaT 0 +RPS10 UCSF GRCh37 6 34389575 34389575 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 143 125 213 0 ENST00000326199.8:c.332G>A p.Gly111Asp p.G111D ENST00000326199 NM_001014.4 111 gGt/gAt 0 +RPS6KA4 UCSF GRCh37 11 64129475 64129475 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 34 91 0 ENST00000334205.4:c.906+1G>A p.X302_splice ENST00000334205 NM_003942.2 0 +RRP15 UCSF GRCh37 1 218480844 218480844 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 72 137 0 ENST00000366932.3:c.575G>A p.Gly192Glu p.G192E ENST00000366932 NM_016052.3 192 gGa/gAa 0 +RSAD1 UCSF GRCh37 17 48559649 48559649 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 43 100 0 ENST00000258955.2:c.672C>T p.Ser224= p.S224= ENST00000258955 NM_018346.1 224 tcC/tcT 0 +RSPH10B UCSF GRCh37 7 5967960 5967960 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 583 156 606 0 ENST00000405415.1:c.2299G>A p.Val767Ile p.V767I ENST00000405415 767 Gtc/Atc 0 +RSU1 UCSF GRCh37 10 16794618 16794618 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 293 169 279 0 ENST00000377921.3:c.518C>T p.Pro173Leu p.P173L ENST00000377921 173 cCt/cTt 0 +RTCD1 UCSF GRCh37 1 100757039 100757039 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 158 114 257 0 ENST00000260563.4:c.1119G>A p.Gly373= p.G373= ENST00000260563 NM_001130841.1 373 ggG/ggA 0 +RTL1 UCSF GRCh37 14 101348097 101348097 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 80 187 0 ENST00000534062.1:c.3029C>T p.Ala1010Val p.A1010V ENST00000534062 NM_001134888.2 1010 gCc/gTc 0 +RUFY2 UCSF GRCh37 10 70115139 70115139 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 21 108 0 ENST00000388768.2:c.1675G>A p.Asp559Asn p.D559N ENST00000388768 NM_017987.4 559 Gac/Aac 0 +RUSC1 UCSF GRCh37 1 155296523 155296523 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 49 126 0 ENST00000368352.5:c.2014C>T p.Pro672Ser p.P672S ENST00000368352 NM_001105203.1 672 Ccc/Tcc 0 +RYR1 UCSF GRCh37 19 38964107 38964107 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 22 72 0 ENST00000359596.3:c.3856C>T p.Leu1286Phe p.L1286F ENST00000359596 1286 Ctt/Ttt 0 +RYR2 UCSF GRCh37 1 237811891 237811891 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 67 136 0 ENST00000366574.2:c.7490G>A p.Arg2497Gln p.R2497Q ENST00000366574 NM_001035.2 2497 cGg/cAg 0 +RYR3 UCSF GRCh37 15 34023823 34023823 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 186 124 280 0 ENST00000389232.4:c.7352G>A p.Arg2451Lys p.R2451K ENST00000389232 NM_001036.3 2451 aGg/aAg 0 +RYR3 UCSF GRCh37 15 33936690 33936690 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 111 85 221 0 ENST00000389232.4:c.3735C>T p.Val1245= p.V1245= ENST00000389232 NM_001036.3 1245 gtC/gtT 0 +S100A7 UCSF GRCh37 1 153430419 153430419 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 195 30 176 1 ENST00000368723.3:c.169G>A p.Asp57Asn p.D57N ENST00000368723 NM_002963.3 57 Gat/Aat 0 +S100A7 UCSF GRCh37 1 153430418 153430418 + missense_variant Missense_Mutation SNP T T G NOVEL P18_Rec Untested WXS Illumina HiSeq 196 33 178 0 ENST00000368723.3:c.170A>C p.Asp57Ala p.D57A ENST00000368723 NM_002963.3 57 gAt/gCt 0 +S100A7 UCSF GRCh37 1 153430338 153430338 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.003,snp132_rs56232841 P18_Rec Untested WXS Illumina HiSeq 158 52 146 0 ENST00000368723.3:c.250A>G p.Thr84Ala p.T84A ENST00000368723 NM_002963.3 84 Aca/Gca 0 +S100A7 UCSF GRCh37 1 153430309 153430309 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 139 38 125 0 ENST00000368723.3:c.279A>G p.Ala93= p.A93= ENST00000368723 NM_002963.3 93 gcA/gcG 0 +S1PR3 UCSF GRCh37 9 91616518 91616518 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 63 138 0 ENST00000375846.3:c.403G>A p.Glu135Lys p.E135K ENST00000375846 135 Gag/Aag 0 +S1PR5 UCSF GRCh37 19 10625409 10625409 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 12 29 0 ENST00000439028.3:c.279C>T p.Ile93= p.I93= ENST00000439028 NM_001166215.1 93 atC/atT 0 +SAFB UCSF GRCh37 19 5653197 5653197 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 55 115 0 ENST00000588852.1:c.1365C>T p.Ser455= p.S455= ENST00000588852 455 tcC/tcT 0 +SALL3 UCSF GRCh37 18 76753259 76753259 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 28 29 50 1 ENST00000537592.2:c.1268G>A p.Arg423His p.R423H ENST00000537592 NM_171999.3 423 cGc/cAc 0 +SAMD11 UCSF GRCh37 1 865678 865678 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 5 20 0 ENST00000342066.3:c.216G>A p.Lys72= p.K72= ENST00000342066 NM_152486.2 72 aaG/aaA 0 +SAMD15 UCSF GRCh37 14 77844599 77844599 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 143 129 269 0 ENST00000216471.4:c.838C>T p.Pro280Ser p.P280S ENST00000216471 NM_001010860.1 280 Cct/Tct 0 +SAMD9L UCSF GRCh37 7 92763754 92763754 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 143 99 195 0 ENST00000318238.4:c.1531C>T p.Pro511Ser p.P511S ENST00000318238 NM_152703.2 511 Cct/Tct 0 +SARS2 UCSF GRCh37 19 39421155 39421155 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 49 34 91 0 ENST00000600042.1:c.222G>A p.Leu74= p.L74= ENST00000600042 NM_001145901.1 74 ctG/ctA 0 +SART1 UCSF GRCh37 11 65743941 65743941 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 27 17 54 0 ENST00000312397.5:c.1648G>A p.Ala550Thr p.A550T ENST00000312397 NM_005146.4 550 Gcc/Acc 0 +SBF1 UCSF GRCh37 22 50893824 50893824 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 23 58 0 ENST00000380817.3:c.4383G>A p.Val1461= p.V1461= ENST00000380817 NM_002972.2 1461 gtG/gtA 0 +SBK2 UCSF GRCh37 19 56041272 56041272 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 6 15 0 ENST00000413299.1:c.875C>T p.Pro292Leu p.P292L ENST00000413299 NM_001101401.2 292 cCc/cTc 0 +SCAI UCSF GRCh37 9 127783049 127783049 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 76 164 0 ENST00000373549.4:c.582-1G>A p.X194_splice ENST00000373549 NM_173690.4 0 +SCAPER UCSF GRCh37 15 77067433 77067433 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 82 189 0 ENST00000563290.1:c.798G>A p.Glu266= p.E266= ENST00000563290 266 gaG/gaA 0 +SCLY UCSF GRCh37 2 238973011 238973011 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 41 119 0 ENST00000254663.6:c.127G>A p.Asp43Asn p.D43N ENST00000254663 NM_016510.5 43 Gac/Aac 0 +SCN3A UCSF GRCh37 2 166003442 166003442 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 162 104 243 0 ENST00000283254.7:c.1478C>T p.Ser493Phe p.S493F ENST00000283254 NM_001081676.1 493 tCc/tTc 0 +SCNN1D UCSF GRCh37 1 1223152 1223152 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 6 13 0 ENST00000379116.5:c.1499C>T p.Pro500Leu p.P500L ENST00000379116 NM_001130413.3 500 cCc/cTc 0 +SCO2 UCSF GRCh37 22 50962564 50962564 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 43 81 0 ENST00000543927.1:c.277G>A p.Ala93Thr p.A93T ENST00000543927 NM_001169109.1 93 Gcc/Acc 0 +SCOC UCSF GRCh37 4 141300319 141300319 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 199 142 313 0 ENST00000608372.1:c.226C>T p.Pro76Ser p.P76S ENST00000608372 76 Ccc/Tcc 0 +SCRIB UCSF GRCh37 8 144873903 144873903 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 19 48 0 ENST00000356994.2:c.4703C>T p.Ser1568Phe p.S1568F ENST00000356994 NM_182706.4 1568 tCt/tTt 0 +SCYL1 UCSF GRCh37 11 65293669 65293669 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 33 71 0 ENST00000270176.5:c.450C>T p.Asp150= p.D150= ENST00000270176 NM_020680.3 150 gaC/gaT 0 +SDC4 UCSF GRCh37 20 43964433 43964433 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 54 122 0 ENST00000372733.3:c.188C>T p.Ser63Phe p.S63F ENST00000372733 NM_002999.3 63 tCt/tTt 0 +SDCCAG3 UCSF GRCh37 9 139301615 139301615 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 22 78 0 ENST00000357365.3:c.801G>A p.Leu267= p.L267= ENST00000357365 NM_001039707.1 267 ctG/ctA 0 +SDK1 UCSF GRCh37 7 4119212 4119212 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 68 168 0 ENST00000404826.2:c.3320G>A p.Gly1107Glu p.G1107E ENST00000404826 NM_152744.3 1107 gGg/gAg 0 +SEBOX UCSF GRCh37 17 26691913 26691913 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 30 58 0 ENST00000555059.2:c.394G>A p.Gly132Arg p.G132R ENST00000555059 132 Gga/Aga 0 +SEC11A UCSF GRCh37 15 85223946 85223946 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 158 111 232 0 ENST00000268220.7:c.429G>A p.Arg143= p.R143= ENST00000268220 NM_014300.3 143 agG/agA 0 +SEC13 UCSF GRCh37 3 10346745 10346745 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 40 87 0 ENST00000350697.3:c.680C>T p.Pro227Leu p.P227L ENST00000350697 NM_183352.2 227 cCc/cTc 0 +SEC14L6 UCSF GRCh37 22 30921822 30921822 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 40 111 0 ENST00000402034.2:c.762C>T p.Cys254= p.C254= ENST00000402034 NM_001193336.2 254 tgC/tgT 0 +SEC16A UCSF GRCh37 9 139361486 139361486 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 86 178 0 ENST00000313050.7:c.3852C>T p.Pro1284= p.P1284= ENST00000313050 NM_014866.1 1284 ccC/ccT 0 +SEC22A UCSF GRCh37 3 122928095 122928095 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 79 162 0 ENST00000309934.4:c.31C>T p.Arg11Cys p.R11C ENST00000309934 NM_012430.4 11 Cgt/Tgt 0 +SEC24B UCSF GRCh37 4 110394304 110394304 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 83 171 0 ENST00000265175.5:c.1022C>T p.Thr341Ile p.T341I ENST00000265175 NM_006323.2 341 aCc/aTc 0 +SEC24D UCSF GRCh37 4 119718875 119718875 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 69 158 0 ENST00000280551.6:c.1004C>T p.Ala335Val p.A335V ENST00000280551 335 gCt/gTt 0 +SEC31A UCSF GRCh37 4 83799897 83799897 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 71 150 0 ENST00000395310.2:c.388G>A p.Val130Met p.V130M ENST00000395310 NM_001077207.2 130 Gtg/Atg 0 +SEC31B UCSF GRCh37 10 102258480 102258480 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 75 146 0 ENST00000370345.3:c.1666G>A p.Glu556Lys p.E556K ENST00000370345 NM_015490.3 556 Gag/Aag 0 +SEC61A1 UCSF GRCh37 3 127785931 127785931 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 142 94 194 0 ENST00000243253.3:c.912C>T p.Ile304= p.I304= ENST00000243253 NM_013336.3 304 atC/atT 0 +SELE UCSF GRCh37 1 169698710 169698710 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 91 175 0 ENST00000333360.7:c.820G>A p.Glu274Lys p.E274K ENST00000333360 NM_000450.2 274 Gaa/Aaa 0 +SELV UCSF GRCh37 19 40009788 40009788 + stop_retained_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 35 74 0 ENST00000335426.4:c.1041G>A p.Ter347= p.*347= ENST00000335426 NM_182704.1 347 taG/taA 0 +SEMA3E UCSF GRCh37 7 83047781 83047781 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 36 61 0 ENST00000307792.3:c.475G>A p.Glu159Lys p.E159K ENST00000307792 NM_012431.2 159 Gaa/Aaa 0 +SEMA4A UCSF GRCh37 1 156128558 156128558 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 156 99 220 0 ENST00000368285.3:c.511G>A p.Glu171Lys p.E171K ENST00000368285 NM_001193300.1 171 Gag/Aag 0 +SEMA4B UCSF GRCh37 15 90764230 90764230 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 47 98 0 ENST00000411539.2:c.500C>T p.Thr167Ile p.T167I ENST00000411539 NM_198925.2 167 aCc/aTc 0 +SEMA4C UCSF GRCh37 2 97529843 97529843 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 24 60 0 ENST00000305476.5:c.1150C>T p.Leu384= p.L384= ENST00000305476 NM_017789.4 384 Ctg/Ttg 0 +SEMA4D UCSF GRCh37 9 91978436 91978436 + downstream_gene_variant 3'Flank SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 26 60 0 ENST00000375807 NM_024077.3 0 +SEMA5A UCSF GRCh37 5 9122932 9122932 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 47 117 0 ENST00000382496.5:c.1617G>A p.Val539= p.V539= ENST00000382496 NM_003966.2 539 gtG/gtA 0 +SEMA6C UCSF GRCh37 1 151105838 151105838 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 8 19 0 ENST00000368913.3:c.2011G>A p.Asp671Asn p.D671N ENST00000368913 NM_001178061.1 671 Gac/Aac 0 +SEMA6D UCSF GRCh37 15 48056446 48056446 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 83 151 0 ENST00000316364.5:c.1041G>A p.Gln347= p.Q347= ENST00000316364 NM_153618.1 347 caG/caA 0 +SEMG2 UCSF GRCh37 20 43852008 43852008 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 58 138 0 ENST00000372769.3:c.1735C>T p.Pro579Ser p.P579S ENST00000372769 NM_003008.2 579 Cca/Tca 0 +SEPN1 UCSF GRCh37 1 26131720 26131720 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 59 146 0 ENST00000361547.2:c.491C>T p.Pro164Leu p.P164L ENST00000361547 NM_020451.2 164 cCt/cTt 0 +SEPT1 UCSF GRCh37 16 30392662 30392662 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 74 94 0 ENST00000321367.3:c.579G>A p.Arg193= p.R193= ENST00000321367 NM_052838.4 193 cgG/cgA 0 +SEPT3 UCSF GRCh37 22 42388723 42388723 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 13 45 0 ENST00000396426.3:c.821G>A p.Gly274Asp p.G274D ENST00000396426 NM_145733.2 274 gGc/gAc 0 +SEPT3 UCSF GRCh37 22 42382070 42382070 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 29 57 0 ENST00000396426.3:c.285G>A p.Arg95= p.R95= ENST00000396426 NM_145733.2 95 cgG/cgA 0 +SERAC1 UCSF GRCh37 6 158576362 158576362 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 39 90 0 ENST00000367104.3:c.113G>A p.Gly38Glu p.G38E ENST00000367104 NM_032861.3 38 gGa/gAa 0 +SERPINB12 UCSF GRCh37 18 61228327 61228327 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 139 111 262 0 ENST00000269491.1:c.394G>A p.Asp132Asn p.D132N ENST00000269491 NM_080474.1 132 Gat/Aat 0 +SERPINB3 UCSF GRCh37 18 61323037 61323037 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 144 104 202 0 ENST00000283752.5:c.1027G>A p.Ala343Thr p.A343T ENST00000283752 NM_006919.2 343 Gct/Act 0 +SERPINF1 UCSF GRCh37 17 1675304 1675304 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 36 107 0 ENST00000254722.4:c.578C>T p.Ala193Val p.A193V ENST00000254722 NM_002615.5 193 gCc/gTc 0 +SETBP1 UCSF GRCh37 18 42531407 42531407 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 61 107 0 ENST00000282030.5:c.2102G>A p.Gly701Glu p.G701E ENST00000282030 NM_015559.2 701 gGg/gAg 0 +SETD1A UCSF GRCh37 16 30977303 30977303 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 54 143 0 ENST00000262519.8:c.2101G>A p.Ala701Thr p.A701T ENST00000262519 NM_014712.1 701 Gcc/Acc 0 +SETMAR UCSF GRCh37 3 4355176 4355176 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 352 86 190 0 ENST00000358065.4:c.751G>A p.Asp251Asn p.D251N ENST00000358065 NM_006515.3 251 Gat/Aat 0 +SEZ6 UCSF GRCh37 17 27286898 27286898 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 24 54 0 ENST00000317338.12:c.1589G>A p.Gly530Asp p.G530D ENST00000317338 530 gGc/gAc 0 +SF3B2 UCSF GRCh37 11 65824827 65824827 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 77 160 0 ENST00000322535.6:c.758C>T p.Pro253Leu p.P253L ENST00000322535 NM_006842.2 253 cCt/cTt 0 +SFSWAP UCSF GRCh37 12 132237854 132237854 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 50 89 0 ENST00000541286.1:c.1268C>T p.Pro423Leu p.P423L ENST00000541286 NM_001261411.1 423 cCc/cTc 0 +SFTPA1 UCSF GRCh37 10 81371624 81371624 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 85 173 0 ENST00000419470.2:c.88G>A p.Ala30Thr p.A30T ENST00000419470 30 Gcc/Acc 0 +SFTPA2 UCSF GRCh37 10 81319071 81319071 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 48 134 0 ENST00000372325.2:c.169C>T p.Pro57Ser p.P57S ENST00000372325 NM_001098668.2 57 Cca/Tca 0 +SGIP1 UCSF GRCh37 1 67195022 67195022 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0022 P18_Rec Untested WXS Illumina HiSeq 113 81 185 0 ENST00000371037.4:c.1818G>A p.Pro606= p.P606= ENST00000371037 NM_032291.2 606 ccG/ccA 0 +SGK223 UCSF GRCh37 8 8185635 8185635 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 158 124 201 0 ENST00000520004.1:c.2657G>A p.Gly886Asp p.G886D ENST00000520004 886 gGc/gAc 0 +SGK223 UCSF GRCh37 8 8185896 8185896 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 39 87 0 ENST00000520004.1:c.2396C>T p.Thr799Ile p.T799I ENST00000520004 799 aCt/aTt 0 +SGK223 UCSF GRCh37 8 8176294 8176294 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 12 9 35 0 ENST00000520004.1:c.3591G>A p.Pro1197= p.P1197= ENST00000520004 1197 ccG/ccA 0 +SGMS1 UCSF GRCh37 10 52067029 52067029 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 48 94 0 ENST00000361781.2:c.1115G>A p.Arg372Lys p.R372K ENST00000361781 NM_147156.3 372 aGg/aAg 0 +SGPL1 UCSF GRCh37 10 72619236 72619236 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 44 107 0 ENST00000373202.3:c.595G>A p.Gly199Arg p.G199R ENST00000373202 NM_003901.3 199 Gga/Aga 0 +SGPP2 UCSF GRCh37 2 223423585 223423585 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 72 154 0 ENST00000321276.7:c.1168C>T p.Pro390Ser p.P390S ENST00000321276 NM_152386.2 390 Ccg/Tcg 0 +SH3BP4 UCSF GRCh37 2 235949844 235949844 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 102 61 153 0 ENST00000409212.1:c.431G>A p.Gly144Glu p.G144E ENST00000409212 144 gGa/gAa 0 +SH3BP4 UCSF GRCh37 2 235949878 235949878 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 66 165 0 ENST00000409212.1:c.465G>A p.Met155Ile p.M155I ENST00000409212 155 atG/atA 0 +SH3RF2 UCSF GRCh37 5 145442142 145442142 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 73 53 119 0 ENST00000511217.1:c.2068G>A p.Ala690Thr p.A690T ENST00000511217 690 Gcc/Acc 0 +SHANK1 UCSF GRCh37 19 51172385 51172385 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 6 8 16 0 ENST00000293441.1:c.2832C>T p.Arg944= p.R944= ENST00000293441 NM_016148.2 944 cgC/cgT 0 +SHANK2 UCSF GRCh37 11 70319358 70319358 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 48 126 0 ENST00000338508.4:c.5169G>A p.Leu1723= p.L1723= ENST00000338508 1723 ctG/ctA 0 +SHC1 UCSF GRCh37 1 154942558 154942558 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 61 133 0 ENST00000448116.2:c.445C>T p.Leu149= p.L149= ENST00000448116 NM_001130040.1 149 Ctg/Ttg 0 +SHC2 UCSF GRCh37 19 422180 422180 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 26 45 0 ENST00000264554.6:c.1586C>T p.Pro529Leu p.P529L ENST00000264554 NM_012435.2 529 cCc/cTc 0 +SHD UCSF GRCh37 19 4288240 4288240 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 63 25 97 0 ENST00000543264.2:c.717G>A p.Pro239= p.P239= ENST00000543264 NM_020209.3 239 ccG/ccA 0 +SHMT1 UCSF GRCh37 17 18250882 18250882 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 80 190 0 ENST00000316694.3:c.447G>A p.Leu149= p.L149= ENST00000316694 NM_004169.3 149 ctG/ctA 0 +SHROOM3 UCSF GRCh37 4 77700237 77700237 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 76 168 0 ENST00000296043.6:c.5898C>T p.Ala1966= p.A1966= ENST00000296043 NM_020859.3 1966 gcC/gcT 0 +SI UCSF GRCh37 3 164750338 164750338 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 68 180 0 ENST00000264382.3:c.2708C>T p.Ser903Phe p.S903F ENST00000264382 NM_001041.3 903 tCc/tTc 0 +SIGLEC1 UCSF GRCh37 20 3677521 3677521 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 39 22 50 0 ENST00000344754.4:c.2395C>T p.Pro799Ser p.P799S ENST00000344754 NM_023068.3 799 Cca/Tca 0 +SIK1 UCSF GRCh37 21 44839319 44839319 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 24 18 46 0 ENST00000270162.6:c.1159G>A p.Ala387Thr p.A387T ENST00000270162 NM_173354.3 387 Gcc/Acc 0 +SIK2 UCSF GRCh37 11 111591297 111591297 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 95 76 157 0 ENST00000304987.3:c.1591G>A p.Asp531Asn p.D531N ENST00000304987 NM_015191.1 531 Gac/Aac 0 +SIL1 UCSF GRCh37 5 138282962 138282962 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 41 23 79 0 ENST00000394817.2:c.1230C>T p.Asp410= p.D410= ENST00000394817 NM_022464.4 410 gaC/gaT 0 +SIN3A UCSF GRCh37 15 75715130 75715130 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 31 141 0 ENST00000394947.3:c.224G>A p.Gly75Glu p.G75E ENST00000394947 NM_001145358.1 75 gGg/gAg 0 +SIPA1L1 UCSF GRCh37 14 72196876 72196876 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 60 175 1 ENST00000555818.1:c.4782G>A p.Arg1594= p.R1594= ENST00000555818 NM_015556.1 1594 agG/agA 0 +SIPA1L3 UCSF GRCh37 19 38597280 38597280 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 58 116 0 ENST00000222345.6:c.2133G>A p.Gln711= p.Q711= ENST00000222345 NM_015073.1 711 caG/caA 0 +SKAP2 UCSF GRCh37 7 26778483 26778483 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 81 163 0 ENST00000345317.2:c.400G>A p.Gly134Arg p.G134R ENST00000345317 NM_003930.3 134 Gga/Aga 0 +SKI UCSF GRCh37 1 2235395 2235395 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 18 36 0 ENST00000378536.4:c.1328C>T p.Pro443Leu p.P443L ENST00000378536 NM_003036.3 443 cCc/cTc 0 +SKIV2L UCSF GRCh37 6 31936246 31936246 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 50 92 0 ENST00000375394.2:c.3000C>T p.Leu1000= p.L1000= ENST00000375394 NM_006929.4 1000 ctC/ctT 0 +SKIV2L UCSF GRCh37 6 31928217 31928217 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 173 135 282 0 ENST00000375394.2:c.363G>A p.Leu121= p.L121= ENST00000375394 NM_006929.4 121 ctG/ctA 0 +SKIV2L2 UCSF GRCh37 5 54640934 54640934 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 32 84 0 ENST00000230640.5:c.1018G>A p.Glu340Lys p.E340K ENST00000230640 NM_015360.4 340 Gaa/Aaa 0 +SLAMF1 UCSF GRCh37 1 160607134 160607134 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 88 193 0 ENST00000302035.6:c.262C>T p.Pro88Ser p.P88S ENST00000302035 NM_003037.2 88 Cct/Tct 0 +SLAMF6 UCSF GRCh37 1 160465922 160465922 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 99 178 0 ENST00000368057.3:c.311C>T p.Thr104Ile p.T104I ENST00000368057 104 aCa/aTa 0 +SLC12A3 UCSF GRCh37 16 56913080 56913080 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 44 10 54 1 ENST00000438926.2:c.1276A>G p.Asn426Asp p.N426D ENST00000438926 NM_001126108.1 426 Aac/Gac 0 +SLC14A2 UCSF GRCh37 18 43212405 43212405 + missense_variant Missense_Mutation SNP G G T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 89 212 0 ENST00000255226.6:c.612G>T p.Trp204Cys p.W204C ENST00000255226 NM_007163.3 204 tgG/tgT 0 +SLC15A1 UCSF GRCh37 13 99361913 99361913 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 61 146 0 ENST00000376503.5:c.980C>T p.Thr327Ile p.T327I ENST00000376503 NM_005073.3 327 aCc/aTc 0 +SLC15A2 UCSF GRCh37 3 121659250 121659250 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 52 113 0 ENST00000489711.1:c.1928C>T p.Ser643Phe p.S643F ENST00000489711 NM_021082.3 643 tCt/tTt 0 +SLC15A3 UCSF GRCh37 11 60706981 60706981 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 39 21 63 0 ENST00000227880.3:c.1406G>A p.Gly469Glu p.G469E ENST00000227880 NM_016582.2 469 gGg/gAg 0 +SLC16A1 UCSF GRCh37 1 113464699 113464699 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 73 149 0 ENST00000538576.1:c.274G>A p.Gly92Ser p.G92S ENST00000538576 NM_001166496.1 92 Ggt/Agt 0 +SLC17A3 UCSF GRCh37 6 25850111 25850111 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 92 201 0 ENST00000397060.4:c.1193C>T p.Ala398Val p.A398V ENST00000397060 NM_001098486.1 398 gCc/gTc 0 +SLC17A9 UCSF GRCh37 20 61588814 61588814 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 36 85 0 ENST00000370351.4:c.279C>T p.Ile93= p.I93= ENST00000370351 NM_022082.3 93 atC/atT 0 +SLC18A3 UCSF GRCh37 10 50819055 50819055 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 35 81 0 ENST00000374115.3:c.269C>T p.Ala90Val p.A90V ENST00000374115 NM_003055.2 90 gCc/gTc 0 +SLC19A3 UCSF GRCh37 2 228564098 228564098 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 140 120 262 0 ENST00000258403.3:c.333C>T p.Phe111= p.F111= ENST00000258403 NM_025243.3 111 ttC/ttT 0 +SLC1A7 UCSF GRCh37 1 53569205 53569205 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 14 6 24 0 ENST00000371494.4:c.510C>T p.Pro170= p.P170= ENST00000371494 NM_006671.4 170 ccC/ccT 0 +SLC1A7 UCSF GRCh37 1 53558287 53558287 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 43 92 0 ENST00000371494.4:c.970C>T p.Pro324Ser p.P324S ENST00000371494 NM_006671.4 324 Ccc/Tcc 0 +SLC22A23 UCSF GRCh37 6 3324091 3324091 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 18 58 0 ENST00000406686.3:c.1059C>T p.Phe353= p.F353= ENST00000406686 NM_015482.1 353 ttC/ttT 0 +SLC22A24 UCSF GRCh37 11 62910949 62910949 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 95 59 186 0 ENST00000417740.1:c.303G>A p.Leu101= p.L101= ENST00000417740 NM_001136506.2 101 ctG/ctA 0 +SLC22A9 UCSF GRCh37 11 63174117 63174117 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 78 120 0 ENST00000279178.3:c.1222G>A p.Ala408Thr p.A408T ENST00000279178 NM_080866.2 408 Gca/Aca 0 +SLC22A9 UCSF GRCh37 11 63176153 63176153 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 53 109 0 ENST00000279178.3:c.1403G>A p.Arg468Lys p.R468K ENST00000279178 NM_080866.2 468 aGa/aAa 0 +SLC22A9 UCSF GRCh37 11 63174096 63174096 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec Untested WXS Illumina HiSeq 104 89 141 0 ENST00000279178.3:c.1201C>G p.Leu401Val p.L401V ENST00000279178 NM_080866.2 401 Ctg/Gtg 0 +SLC23A2 UCSF GRCh37 20 4842731 4842731 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 50 104 0 ENST00000379333.1:c.1487G>A p.Gly496Glu p.G496E ENST00000379333 NM_203327.1 496 gGa/gAa 0 +SLC24A1 UCSF GRCh37 15 65917613 65917613 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 66 174 0 ENST00000261892.6:c.1195C>T p.Pro399Ser p.P399S ENST00000261892 NM_004727.2 399 Cca/Tca 0 +SLC24A1 UCSF GRCh37 15 65943185 65943185 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 79 201 0 ENST00000261892.6:c.2698G>A p.Asp900Asn p.D900N ENST00000261892 NM_004727.2 900 Gac/Aac 0 +SLC24A3 UCSF GRCh37 20 19261715 19261715 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 45 130 0 ENST00000328041.6:c.255G>A p.Lys85= p.K85= ENST00000328041 NM_020689.3 85 aaG/aaA 0 +SLC24A6 UCSF GRCh37 12 113744348 113744348 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 37 39 67 0 ENST00000552014.1:c.1444G>A p.Gly482Ser p.G482S ENST00000552014 482 Ggc/Agc 0 +SLC24A6 UCSF GRCh37 12 113753213 113753213 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 6 9 20 0 ENST00000552014.1:c.1062G>A p.Trp354Ter p.W354* ENST00000552014 354 tgG/tgA 0 +SLC25A13 UCSF GRCh37 7 95799390 95799390 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 113 237 0 ENST00000416240.2:c.1281C>T p.Val427= p.V427= ENST00000416240 NM_014251.2 427 gtC/gtT 0 +SLC25A32 UCSF GRCh37 8 104417054 104417054 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 39 98 0 ENST00000297578.4:c.341G>A p.Arg114Lys p.R114K ENST00000297578 NM_030780.4 114 aGa/aAa 0 +SLC26A2 UCSF GRCh37 5 149360728 149360728 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 174 152 280 0 ENST00000286298.4:c.1572G>A p.Leu524= p.L524= ENST00000286298 NM_000112.3 524 ctG/ctA 0 +SLC26A7 UCSF GRCh37 8 92307932 92307932 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 57 118 0 ENST00000309536.2:c.477+1G>A p.X159_splice ENST00000309536 NM_134266.1 0 +SLC27A4 UCSF GRCh37 9 131107677 131107677 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 45 31 58 0 ENST00000300456.4:c.405C>T p.Asn135= p.N135= ENST00000300456 NM_005094.3 135 aaC/aaT 0 +SLC29A1 UCSF GRCh37 6 44199835 44199835 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 51 92 0 ENST00000393841.1:c.965G>A p.Ser322Asn p.S322N ENST00000393841 NM_001078177.1 322 aGc/aAc 0 +SLC2A1 UCSF GRCh37 1 43395384 43395384 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 76 161 0 ENST00000426263.3:c.747G>A p.Arg249= p.R249= ENST00000426263 NM_006516.2 249 cgG/cgA 0 +SLC35A5 UCSF GRCh37 3 112299912 112299912 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 75 193 0 ENST00000492406.1:c.948G>A p.Gln316= p.Q316= ENST00000492406 NM_017945.3 316 caG/caA 0 +SLC35B2 UCSF GRCh37 6 44223172 44223172 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 92 161 0 ENST00000393812.3:c.570C>T p.Ser190= p.S190= ENST00000393812 NM_178148.2 190 agC/agT 0 +SLC35C2 UCSF GRCh37 20 44979157 44979157 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 45 106 0 ENST00000372227.1:c.974G>A p.Gly325Asp p.G325D ENST00000372227 NM_001281460.1 325 gGt/gAt 0 +SLC35D2 UCSF GRCh37 9 99106194 99106194 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 155 126 318 0 ENST00000253270.7:c.676C>T p.Leu226= p.L226= ENST00000253270 NM_007001.2 226 Ctg/Ttg 0 +SLC36A3 UCSF GRCh37 5 150663711 150663711 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 152 101 237 0 ENST00000377713.3:c.991G>A p.Gly331Arg p.G331R ENST00000377713 NM_001145017.1 331 Ggg/Agg 0 +SLC38A1 UCSF GRCh37 12 46582843 46582843 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 17 95 204 0 ENST00000398637.5:c.1374C>T p.Phe458= p.F458= ENST00000398637 NM_030674.3 458 ttC/ttT 0 +SLC38A7 UCSF GRCh37 16 58701337 58701337 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 61 103 0 ENST00000570101.1:c.1341C>T p.Ile447= p.I447= ENST00000570101 447 atC/atT 0 +SLC39A1 UCSF GRCh37 1 153932594 153932594 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 64 125 0 ENST00000368623.3:c.955C>T p.Leu319= p.L319= ENST00000368623 319 Ctg/Ttg 0 +SLC39A13 UCSF GRCh37 11 47436366 47436366 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 40 138 0 ENST00000362021.4:c.825C>T p.Asp275= p.D275= ENST00000362021 NM_001128225.2 275 gaC/gaT 0 +SLC39A4 UCSF GRCh37 8 145641309 145641309 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 4 19 0 ENST00000301305.3:c.359C>T p.Ala120Val p.A120V ENST00000301305 NM_130849.3 120 gCc/gTc 0 +SLC41A2 UCSF GRCh37 12 105239662 105239662 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 66 131 0 ENST00000258538.3:c.1346C>T p.Pro449Leu p.P449L ENST00000258538 NM_032148.3 449 cCc/cTc 0 +SLC44A2 UCSF GRCh37 19 10748407 10748407 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 99 76 200 0 ENST00000335757.5:c.1679G>A p.Arg560Lys p.R560K ENST00000335757 560 aGg/aAg 0 +SLC44A4 UCSF GRCh37 6 31831431 31831431 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 23 42 0 ENST00000229729.6:c.2106C>T p.Pro702= p.P702= ENST00000229729 NM_025257.2 702 ccC/ccT 0 +SLC4A4 UCSF GRCh37 4 72429552 72429552 + intron_variant Intron SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 151 110 223 0 ENST00000425175.1:c.3100-3169C>T *1034* ENST00000425175 NM_001134742.1 0 +SLC4A4 UCSF GRCh37 4 72432773 72432773 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 49 138 0 ENST00000425175.1:c.3152C>T p.Pro1051Leu p.P1051L ENST00000425175 NM_001134742.1 1051 cCt/cTt 0 +SLC5A10 UCSF GRCh37 17 18922759 18922759 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 16 48 0 ENST00000395647.2:c.1313G>A p.Gly438Asp p.G438D ENST00000395647 NM_152351.4 438 gGc/gAc 0 +SLC5A3 UCSF GRCh37 21 35469301 35469301 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 155 99 238 0 ENST00000381151.3:c.1804G>A p.Asp602Asn p.D602N ENST00000381151 602 Gat/Aat 0 +SLC5A5 UCSF GRCh37 19 17986914 17986914 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 40 79 0 ENST00000222248.3:c.697G>A p.Asp233Asn p.D233N ENST00000222248 NM_000453.2 233 Gac/Aac 0 +SLC5A8 UCSF GRCh37 12 101603315 101603315 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 32 27 48 0 ENST00000536262.2:c.312C>T p.Leu104= p.L104= ENST00000536262 NM_145913.3 104 ctC/ctT 0 +SLC6A18 UCSF GRCh37 5 1243822 1243822 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 41 76 0 ENST00000324642.3:c.1284C>T p.Pro428= p.P428= ENST00000324642 NM_182632.2 428 ccC/ccT 0 +SLC6A3 UCSF GRCh37 5 1422087 1422087 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 62 125 0 ENST00000270349.9:c.696C>T p.Asp232= p.D232= ENST00000270349 NM_001044.4 232 gaC/gaT 0 +SLC6A5 UCSF GRCh37 11 20628611 20628611 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 36 86 0 ENST00000525748.1:c.738C>T p.Phe246= p.F246= ENST00000525748 NM_004211.3 246 ttC/ttT 0 +SLC9A10 UCSF GRCh37 3 111993771 111993771 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 158 109 209 0 ENST00000305815.5:c.586C>T p.Leu196= p.L196= ENST00000305815 NM_183061.1 196 Cta/Tta 0 +SLC9A3 UCSF GRCh37 5 483527 483527 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 3 23 0 ENST00000264938.3:c.1003G>A p.Val335Met p.V335M ENST00000264938 NM_004174.2 335 Gtg/Atg 0 +SLC9A5 UCSF GRCh37 16 67300129 67300129 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 51 39 80 0 ENST00000299798.11:c.2218+1G>A p.X740_splice ENST00000299798 NM_004594.2 0 +SLFN5 UCSF GRCh37 17 33591579 33591579 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 87 211 0 ENST00000299977.4:c.1516G>A p.Val506Ile p.V506I ENST00000299977 NM_144975.3 506 Gtt/Att 0 +SLIT1 UCSF GRCh37 10 98945240 98945240 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 8 31 0 ENST00000266058.4:c.192G>A p.Glu64= p.E64= ENST00000266058 NM_003061.2 64 gaG/gaA 0 +SLITRK5 UCSF GRCh37 13 88328840 88328840 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 45 120 0 ENST00000325089.6:c.1197G>A p.Glu399= p.E399= ENST00000325089 NM_015567.1 399 gaG/gaA 0 +SLX4 UCSF GRCh37 16 3647861 3647861 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 146 76 132 0 ENST00000294008.3:c.1303G>A p.Gly435Ser p.G435S ENST00000294008 NM_032444.2 435 Ggt/Agt 0 +SMAP2 UCSF GRCh37 1 40882730 40882730 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 44 41 59 0 ENST00000372718.3:c.1126G>A p.Val376Ile p.V376I ENST00000372718 NM_022733.2 376 Gtc/Atc 0 +SMARCA4 UCSF GRCh37 19 11144114 11144114 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 99 70 162 0 ENST00000344626.4:c.3695G>A p.Gly1232Asp p.G1232D ENST00000344626 NM_003072.3 1232 gGc/gAc 0 +SMARCA4 UCSF GRCh37 19 11145748 11145748 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 17 30 0 ENST00000344626.4:c.4110C>T p.Gly1370= p.G1370= ENST00000344626 NM_003072.3 1370 ggC/ggT 0 +SMARCAD1 UCSF GRCh37 4 95173835 95173835 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 33 23 62 0 ENST00000359052.4:c.958C>T p.Pro320Ser p.P320S ENST00000359052 NM_001128430.1 320 Cct/Tct 0 +SMARCB1 UCSF GRCh37 22 24145540 24145540 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 21 67 190 0 ENST00000263121.7:c.559G>A p.Val187Ile p.V187I ENST00000263121 NM_003073.3 187 Gtc/Atc 0 +SMC4 UCSF GRCh37 3 160130152 160130152 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 100 86 161 0 ENST00000357388.3:c.891C>T p.Ala297= p.A297= ENST00000357388 NM_001002800.1 297 gcC/gcT 0 +SMG1 UCSF GRCh37 16 18896968 18896968 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 360 147 308 0 ENST00000446231.2:c.843G>A p.Gln281= p.Q281= ENST00000446231 281 caG/caA 0 +SMG6 UCSF GRCh37 17 2203390 2203390 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 91 200 0 ENST00000263073.6:c.657G>A p.Arg219= p.R219= ENST00000263073 NM_017575.4 219 agG/agA 0 +SMG9 UCSF GRCh37 19 44251867 44251867 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 8 17 0 ENST00000270066.6:c.408G>A p.Glu136= p.E136= ENST00000270066 NM_019108.2 136 gaG/gaA 0 +SMYD2 UCSF GRCh37 1 214504359 214504359 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 80 215 0 ENST00000366957.5:c.883G>A p.Val295Ile p.V295I ENST00000366957 NM_020197.2 295 Gtc/Atc 0 +SNAP25 UCSF GRCh37 20 10279964 10279964 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 96 235 0 ENST00000254976.2:c.456G>A p.Gln152= p.Q152= ENST00000254976 NM_130811.2 152 caG/caA 0 +SNAPC4 UCSF GRCh37 9 139279233 139279233 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 56 184 0 ENST00000298532.2:c.1359G>A p.Lys453= p.K453= ENST00000298532 NM_003086.2 453 aaG/aaA 0 +SNCAIP UCSF GRCh37 5 121787009 121787009 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 79 169 0 ENST00000261368.8:c.2467G>A p.Val823Met p.V823M ENST00000261368 NM_005460.2 823 Gtg/Atg 0 +SNCAIP UCSF GRCh37 5 121758579 121758579 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 62 143 0 ENST00000261368.8:c.147G>A p.Trp49Ter p.W49* ENST00000261368 NM_005460.2 49 tgG/tgA 0 +SND1 UCSF GRCh37 7 127343361 127343361 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 60 116 0 ENST00000354725.3:c.824G>A p.Gly275Asp p.G275D ENST00000354725 NM_014390.2 275 gGt/gAt 0 +SNRNP25 UCSF GRCh37 16 105853 105853 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 28 63 0 ENST00000383018.3:c.237G>A p.Glu79= p.E79= ENST00000383018 NM_024571.3 79 gaG/gaA 0 +SNRPA1 UCSF GRCh37 15 101826467 101826467 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 59 154 0 ENST00000254193.6:c.491G>A p.Gly164Asp p.G164D ENST00000254193 NM_003090.2 164 gGc/gAc 0 +SNRPB UCSF GRCh37 20 2448337 2448337 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 71 169 0 ENST00000438552.2:c.71G>A p.Gly24Asp p.G24D ENST00000438552 NM_198216.1 24 gGc/gAc 0 +SNTG1 UCSF GRCh37 8 51415431 51415431 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 61 108 0 ENST00000522124.1:c.457G>A p.Asp153Asn p.D153N ENST00000522124 NM_018967.2 153 Gat/Aat 0 +SNW1 UCSF GRCh37 14 78198932 78198932 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 67 172 0 ENST00000261531.7:c.787C>T p.Pro263Ser p.P263S ENST00000261531 NM_012245.2 263 Cca/Tca 0 +SNX24 UCSF GRCh37 5 122281781 122281781 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 67 48 90 0 ENST00000261369.4:c.176C>T p.Pro59Leu p.P59L ENST00000261369 NM_014035.2 59 cCt/cTt 0 +SNX27 UCSF GRCh37 1 151638437 151638437 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 116 58 159 0 ENST00000368843.3:c.935G>A p.Ser312Asn p.S312N ENST00000368843 NM_030918.5 312 aGt/aAt 0 +SNX33 UCSF GRCh37 15 75949512 75949512 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 77 156 0 ENST00000308527.5:c.1681G>A p.Gly561Ser p.G561S ENST00000308527 NM_153271.1 561 Ggc/Agc 0 +SOCS6 UCSF GRCh37 18 67992170 67992170 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 88 207 0 ENST00000397942.3:c.266G>A p.Gly89Asp p.G89D ENST00000397942 NM_004232.3 89 gGc/gAc 0 +SON UCSF GRCh37 21 34945614 34945614 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 69 161 0 ENST00000356577.4:c.6886G>A p.Asp2296Asn p.D2296N ENST00000356577 NM_138927.2 2296 Gat/Aat 0 +SORCS1 UCSF GRCh37 10 108357112 108357112 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 41 83 0 ENST00000344440.6:c.3262G>A p.Ala1088Thr p.A1088T ENST00000344440 NM_001206571.1 1088 Gcg/Acg 0 +SORCS3 UCSF GRCh37 10 106802835 106802835 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 90 207 0 ENST00000369701.3:c.977G>A p.Gly326Glu p.G326E ENST00000369701 NM_014978.1 326 gGa/gAa 0 +SOX2 UCSF GRCh37 3 181430304 181430304 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 44 87 0 ENST00000325404.1:c.156C>T p.Ser52= p.S52= ENST00000325404 NM_003106.3 52 tcC/tcT 0 +SOX8 UCSF GRCh37 16 1035317 1035317 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 10 21 0 ENST00000293894.3:c.1272C>T p.Ala424= p.A424= ENST00000293894 NM_014587.3 424 gcC/gcT 0 +SPAG5 UCSF GRCh37 17 26905492 26905492 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 64 146 0 ENST00000321765.5:c.3253G>A p.Glu1085Lys p.E1085K ENST00000321765 NM_006461.3 1085 Gag/Aag 0 +SPATA19 UCSF GRCh37 11 133711925 133711925 + splice_region_variant,3_prime_UTR_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 64 122 0 ENST00000299140.3:c.*9G>A p.X3_splice ENST00000299140 NM_174927.1 0 +SPATA4 UCSF GRCh37 4 177113852 177113852 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 59 149 0 ENST00000280191.2:c.614C>T p.Thr205Ile p.T205I ENST00000280191 NM_144644.2 205 aCc/aTc 0 +SPATA4 UCSF GRCh37 4 177113937 177113937 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 43 101 0 ENST00000280191.2:c.529C>T p.Pro177Ser p.P177S ENST00000280191 NM_144644.2 177 Ccc/Tcc 0 +SPDYE1 UCSF GRCh37 7 44047166 44047166 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 153 84 326 0 ENST00000258704.3:c.932C>T p.Ser311Phe p.S311F ENST00000258704 NM_175064.2 311 tCc/tTc 0 +SPEN UCSF GRCh37 1 16255398 16255398 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 220 163 308 0 ENST00000375759.3:c.2663G>A p.Gly888Glu p.G888E ENST00000375759 NM_015001.2 888 gGa/gAa 0 +SPEN UCSF GRCh37 1 16264397 16264397 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 104 78 160 0 ENST00000375759.3:c.10600G>A p.Ala3534Thr p.A3534T ENST00000375759 NM_015001.2 3534 Gcc/Acc 0 +SPEN UCSF GRCh37 1 16264466 16264466 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 88 70 103 0 ENST00000375759.3:c.10669G>A p.Ala3557Thr p.A3557T ENST00000375759 NM_015001.2 3557 Gca/Aca 0 +SPG11 UCSF GRCh37 15 44887641 44887641 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 49 116 0 ENST00000261866.7:c.4451C>T p.Ser1484Phe p.S1484F ENST00000261866 NM_025137.3 1484 tCt/tTt 0 +SPG20 UCSF GRCh37 13 36886372 36886372 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 111 208 0 ENST00000451493.1:c.1643G>A p.Gly548Glu p.G548E ENST00000451493 NM_001142295.1 548 gGa/gAa 0 +SPHK1 UCSF GRCh37 17 74382100 74382100 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 9 35 0 ENST00000323374.4:c.303C>T p.Cys101= p.C101= ENST00000323374 NM_182965.2 101 tgC/tgT 0 +SPHKAP UCSF GRCh37 2 228883796 228883796 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 82 55 133 0 ENST00000392056.3:c.1774G>A p.Ala592Thr p.A592T ENST00000392056 NM_001142644.1 592 Gca/Aca 0 +SPINK5 UCSF GRCh37 5 147478850 147478850 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 57 51 111 0 ENST00000359874.3:c.1064G>A p.Arg355Lys p.R355K ENST00000359874 NM_001127698.1 355 aGa/aAa 0 +SPINK7 UCSF GRCh37 5 147692956 147692956 + synonymous_variant Silent SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 133 87 197 0 ENST00000274565.4:c.81A>G p.Pro27= p.P27= ENST00000274565 NM_032566.2 27 ccA/ccG 0 +SPINK8 UCSF GRCh37 3 48351427 48351427 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 63 33 78 0 ENST00000434006.1:c.249G>A p.Gly83= p.G83= ENST00000434006 NM_001080525.1 83 ggG/ggA 0 +SPIRE1 UCSF GRCh37 18 12546786 12546786 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 158 126 260 0 ENST00000409402.4:c.490G>A p.Val164Met p.V164M ENST00000409402 NM_001128626.1 164 Gtg/Atg 0 +SPIRE1 UCSF GRCh37 18 12464913 12464913 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 37 71 0 ENST00000409402.4:c.1449C>T p.Pro483= p.P483= ENST00000409402 NM_001128626.1 483 ccC/ccT 0 +SPNS1 UCSF GRCh37 16 28993726 28993726 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 44 134 0 ENST00000311008.11:c.1015C>T p.Leu339= p.L339= ENST00000311008 NM_032038.2 339 Ctg/Ttg 0 +SPRED1 UCSF GRCh37 15 38641642 38641642 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 83 125 0 ENST00000299084.4:c.602G>A p.Gly201Asp p.G201D ENST00000299084 NM_152594.2 201 gGc/gAc 0 +SPTAN1 UCSF GRCh37 9 131394412 131394412 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 22 52 0 ENST00000372739.3:c.6769C>T p.His2257Tyr p.H2257Y ENST00000372739 NM_001130438.2 2257 Cac/Tac 0 +SPTAN1 UCSF GRCh37 9 131349977 131349977 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 42 45 108 0 ENST00000372739.3:c.2871G>A p.Arg957= p.R957= ENST00000372739 NM_001130438.2 957 cgG/cgA 0 +SPTBN5 UCSF GRCh37 15 42179555 42179555 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 18 41 0 ENST00000320955.6:c.744G>A p.Glu248= p.E248= ENST00000320955 NM_016642.3 248 gaG/gaA 0 +SPZ1 UCSF GRCh37 5 79616573 79616573 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 138 97 251 0 ENST00000296739.4:c.539C>T p.Ala180Val p.A180V ENST00000296739 NM_032567.3 180 gCc/gTc 0 +SRCAP UCSF GRCh37 16 30722945 30722945 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 85 150 0 ENST00000262518.4:c.1372G>A p.Gly458Ser p.G458S ENST00000262518 NM_006662.2 458 Ggc/Agc 0 +SRCAP UCSF GRCh37 16 30724618 30724618 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 109 212 0 ENST00000262518.4:c.2220G>A p.Trp740Ter p.W740* ENST00000262518 NM_006662.2 740 tgG/tgA 0 +SRCIN1 UCSF GRCh37 17 36714548 36714548 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 36 79 0 ENST00000264659.7:c.2116G>A p.Asp706Asn p.D706N ENST00000264659 NM_025248.2 706 Gac/Aac 0 +SRCRB4D UCSF GRCh37 7 76027005 76027005 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 25 46 0 ENST00000275560.3:c.698G>A p.Gly233Glu p.G233E ENST00000275560 NM_080744.1 233 gGg/gAg 0 +SREBF1 UCSF GRCh37 17 17723659 17723659 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 31 82 0 ENST00000355815.4:c.358C>T p.Pro120Ser p.P120S ENST00000355815 NM_001005291.2 120 Ccg/Tcg 0 +SREBF1 UCSF GRCh37 17 17723768 17723768 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 43 32 81 0 ENST00000355815.4:c.249G>A p.Gly83= p.G83= ENST00000355815 NM_001005291.2 83 ggG/ggA 0 +SRGAP1 UCSF GRCh37 12 64536263 64536263 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 97 187 0 ENST00000355086.3:c.3069G>A p.Gln1023= p.Q1023= ENST00000355086 NM_020762.2 1023 caG/caA 0 +SRGAP3 UCSF GRCh37 3 9097938 9097938 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 234 62 161 0 ENST00000383836.3:c.1104C>T p.Thr368= p.T368= ENST00000383836 NM_014850.3 368 acC/acT 0 +SRGAP3 UCSF GRCh37 3 9099983 9099983 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 294 79 179 0 ENST00000383836.3:c.975C>T p.Val325= p.V325= ENST00000383836 NM_014850.3 325 gtC/gtT 0 +SRL UCSF GRCh37 16 4247852 4247852 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 128 57 144 0 ENST00000399609.3:c.324C>T p.Thr108= p.T108= ENST00000399609 NM_001098814.1 108 acC/acT 0 +SRRM2 UCSF GRCh37 16 2813421 2813421 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 347 120 279 0 ENST00000301740.8:c.2892G>A p.Leu964= p.L964= ENST00000301740 NM_016333.3 964 ttG/ttA 0 +SRRM3 UCSF GRCh37 7 75914999 75914999 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 13 29 0 ENST00000326382.8:c.*6G>A *2* ENST00000326382 NM_001110199.1 0 +SSBP4 UCSF GRCh37 19 18542824 18542824 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 7 42 0 ENST00000270061.7:c.580G>A p.Gly194Ser p.G194S ENST00000270061 NM_032627.4 194 Ggc/Agc 0 +SSH3 UCSF GRCh37 11 67074528 67074528 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 46 74 0 ENST00000308127.4:c.480C>T p.Thr160= p.T160= ENST00000308127 NM_017857.3 160 acC/acT 0 +SSPO UCSF GRCh37 7 149504001 149504001 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 9 27 0 ENST00000378016.2:n.8825G>A *2942* ENST00000378016 0 +SSTR4 UCSF GRCh37 20 23017130 23017130 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 51 104 0 ENST00000255008.3:c.1010G>A p.Gly337Glu p.G337E ENST00000255008 NM_001052.2 337 gGa/gAa 0 +SSX1 UCSF GRCh37 X 48125757 48125757 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 178 195 0 ENST00000376919.3:c.502C>T p.Leu168= p.L168= ENST00000376919 NM_005635.3 168 Ctg/Ttg 0 +ST3GAL4 UCSF GRCh37 11 126277205 126277205 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 137 106 235 0 ENST00000526727.1:c.241C>T p.Pro81Ser p.P81S ENST00000526727 81 Cca/Tca 0 +STAB1 UCSF GRCh37 3 52540864 52540864 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 31 27 38 0 ENST00000321725.6:c.1987G>A p.Ala663Thr p.A663T ENST00000321725 NM_015136.2 663 Gcg/Acg 0 +STAB1 UCSF GRCh37 3 52536691 52536691 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 39 73 0 ENST00000321725.6:c.531G>A p.Gly177= p.G177= ENST00000321725 NM_015136.2 177 ggG/ggA 0 +STAG3 UCSF GRCh37 7 99778250 99778250 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 198 127 286 0 ENST00000426455.1:c.71C>T p.Ala24Val p.A24V ENST00000426455 NM_001282716.1 24 gCc/gTc 0 +STARD10 UCSF GRCh37 11 72470348 72470348 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 89 61 149 0 ENST00000334805.6:c.286G>A p.Asp96Asn p.D96N ENST00000334805 NM_006645.2 96 Gac/Aac 0 +STARD9 UCSF GRCh37 15 42930238 42930238 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 81 184 0 ENST00000290607.7:c.399G>A p.Arg133= p.R133= ENST00000290607 NM_020759.2 133 agG/agA 0 +STAT3 UCSF GRCh37 17 40475363 40475363 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 83 180 0 ENST00000264657.5:c.1663G>A p.Ala555Thr p.A555T ENST00000264657 NM_139276.2 555 Gct/Act 0 +STAT5B UCSF GRCh37 17 40354446 40354446 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 25 62 0 ENST00000293328.3:c.2149G>A p.Asp717Asn p.D717N ENST00000293328 NM_012448.3 717 Gat/Aat 0 +STIM1 UCSF GRCh37 11 4112853 4112853 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 21 62 158 0 ENST00000300737.4:c.1883C>T p.Ser628Phe p.S628F ENST00000300737 NM_003156.3 628 tCt/tTt 0 +STK11IP UCSF GRCh37 2 220471515 220471515 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 71 161 0 ENST00000295641.10:c.1102C>T p.Pro368Ser p.P368S ENST00000295641 NM_052902.2 368 Cct/Tct 0 +STK32A UCSF GRCh37 5 146763487 146763487 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 90 208 0 ENST00000397936.3:c.1132C>T p.Leu378= p.L378= ENST00000397936 NM_001112724.1 378 Cta/Tta 0 +STOML3 UCSF GRCh37 13 39541032 39541032 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 92 169 0 ENST00000379631.4:c.806C>T p.Pro269Leu p.P269L ENST00000379631 NM_145286.2 269 cCc/cTc 0 +STON1 UCSF GRCh37 2 48809625 48809625 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 76 180 0 ENST00000309835.3:c.1853C>T p.Thr618Ile p.T618I ENST00000309835 618 aCt/aTt 0 +STXBP5 UCSF GRCh37 6 147646219 147646219 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 45 128 0 ENST00000321680.6:c.1927C>T p.Leu643= p.L643= ENST00000321680 NM_001127715.2 643 Ctg/Ttg 0 +SULT2A1 UCSF GRCh37 19 48387013 48387013 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 53 102 0 ENST00000222002.3:c.166C>T p.Leu56= p.L56= ENST00000222002 NM_003167.3 56 Ctg/Ttg 0 +SULT2B1 UCSF GRCh37 19 49100093 49100093 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 16 42 0 ENST00000201586.2:c.743C>T p.Ala248Val p.A248V ENST00000201586 NM_177973.1 248 gCc/gTc 0 +SVIL UCSF GRCh37 10 29756720 29756720 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 167 65 130 0 ENST00000375398.2:c.5928G>A p.Trp1976Ter p.W1976* ENST00000375398 1976 tgG/tgA 0 +SYCE1 UCSF GRCh37 10 135369349 135369349 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 50 110 0 ENST00000343131.5:c.654G>A p.Gly218= p.G218= ENST00000343131 NM_001143764.1 218 ggG/ggA 0 +SYCE2 UCSF GRCh37 19 13011406 13011406 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 126 89 193 0 ENST00000293695.7:c.363C>T p.His121= p.H121= ENST00000293695 NM_001105578.1 121 caC/caT 0 +SYNE1 UCSF GRCh37 6 152603061 152603061 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 60 47 116 0 ENST00000367255.5:c.18262T>C p.Tyr6088His p.Y6088H ENST00000367255 NM_182961.3 6088 Tat/Cat 0 +SYNE1 UCSF GRCh37 6 152545661 152545661 + stop_gained Nonsense_Mutation SNP C C A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 71 205 0 ENST00000367255.5:c.21490G>T p.Glu7164Ter p.E7164* ENST00000367255 NM_182961.3 7164 Gaa/Taa 0 +SYNE2 UCSF GRCh37 14 64469624 64469624 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 86 186 0 ENST00000358025.3:c.3973C>T p.Leu1325= p.L1325= ENST00000358025 NM_182914.2 1325 Ctg/Ttg 0 +SYNGAP1 UCSF GRCh37 6 33412273 33412273 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 52 137 0 ENST00000418600.2:c.3461C>T p.Thr1154Ile p.T1154I ENST00000418600 NM_006772.2 1154 aCa/aTa 0 +SYNGR3 UCSF GRCh37 16 2042036 2042036 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 3 13 0 ENST00000248121.2:c.161G>A p.Gly54Asp p.G54D ENST00000248121 NM_004209.5 54 gGc/gAc 0 +SYNJ1 UCSF GRCh37 21 34038826 34038826 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 182 102 243 0 ENST00000433931.2:c.1986C>T p.Asn662= p.N662= ENST00000433931 NM_003895.3 662 aaC/aaT 0 +SYNJ2 UCSF GRCh37 6 158449942 158449942 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 50 160 0 ENST00000355585.4:c.369C>T p.Ile123= p.I123= ENST00000355585 NM_001178088.1 123 atC/atT 0 +SYT11 UCSF GRCh37 1 155838193 155838193 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 107 215 0 ENST00000368324.4:c.472C>T p.Leu158= p.L158= ENST00000368324 NM_152280.4 158 Cta/Tta 0 +SYT12 UCSF GRCh37 11 66816106 66816106 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 42 66 0 ENST00000393946.2:c.1144G>A p.Asp382Asn p.D382N ENST00000393946 382 Gac/Aac 0 +SYT3 UCSF GRCh37 19 51132555 51132555 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 16 32 0 ENST00000338916.4:c.1277G>A p.Gly426Asp p.G426D ENST00000338916 NM_032298.2 426 gGc/gAc 0 +SZT2 UCSF GRCh37 1 43907023 43907023 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 85 196 0 ENST00000562955.1:c.7312G>A p.Gly2438Ser p.G2438S ENST00000562955 NM_015284.3 2438 Ggc/Agc 0 +T UCSF GRCh37 6 166580152 166580152 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 59 150 0 ENST00000296946.2:c.399G>A p.Gly133= p.G133= ENST00000296946 NM_003181.3 133 ggG/ggA 0 +TAB3 UCSF GRCh37 X 30873508 30873508 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 4 33 43 0 ENST00000378933.1:c.274C>T p.Leu92Phe p.L92F ENST00000378933 NM_152787.3 92 Ctt/Ttt 0 +TACC2 UCSF GRCh37 10 123843783 123843783 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 47 120 0 ENST00000369005.1:c.1768G>A p.Asp590Asn p.D590N ENST00000369005 NM_206862.2 590 Gac/Aac 0 +TADA2A UCSF GRCh37 17 35802719 35802719 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 38 113 0 ENST00000394395.2:c.497C>T p.Ala166Val p.A166V ENST00000394395 NM_001166105.1 166 gCc/gTc 0 +TAF11 UCSF GRCh37 6 34846481 34846481 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 60 147 0 ENST00000361288.4:c.522G>A p.Glu174= p.E174= ENST00000361288 NM_005643.3 174 gaG/gaA 0 +TAF1L UCSF GRCh37 9 32635537 32635537 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 55 131 0 ENST00000242310.4:c.41C>T p.Thr14Ile p.T14I ENST00000242310 NM_153809.2 14 aCc/aTc 0 +TAF4B UCSF GRCh37 18 23866446 23866446 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 108 93 185 0 ENST00000269142.5:c.1573G>A p.Val525Ile p.V525I ENST00000269142 NM_005640.1 525 Gtt/Att 0 +TAGLN UCSF GRCh37 11 117074071 117074071 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 67 156 0 ENST00000532870.1:c.229G>A p.Val77Met p.V77M ENST00000532870 77 Gtg/Atg 0 +TANK UCSF GRCh37 2 162061305 162061305 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 50 137 0 ENST00000392749.2:c.327+1G>A p.X109_splice ENST00000392749 NM_001199135.1 0 +TAOK1 UCSF GRCh37 17 27857551 27857551 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 94 197 0 ENST00000261716.3:c.2275C>T p.Arg759Trp p.R759W ENST00000261716 NM_020791.2 759 Cgg/Tgg 0 +TAOK3 UCSF GRCh37 12 118639265 118639265 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 75 54 121 0 ENST00000392533.3:c.823G>A p.Asp275Asn p.D275N ENST00000392533 NM_016281.3 275 Gac/Aac 0 +TARDBP UCSF GRCh37 1 11082189 11082189 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 86 154 0 ENST00000240185.3:c.723G>A p.Gln241= p.Q241= ENST00000240185 NM_007375.3 241 caG/caA 0 +TAS2R20 UCSF GRCh37 12 11149806 11149806 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 185 155 326 0 ENST00000538986.1:c.669C>T p.Ile223= p.I223= ENST00000538986 NM_176889.2 223 atC/atT 0 +TASP1 UCSF GRCh37 20 13539702 13539702 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 85 180 0 ENST00000337743.4:c.628G>A p.Asp210Asn p.D210N ENST00000337743 NM_017714.2 210 Gac/Aac 0 +TBC1D10A UCSF GRCh37 22 30700641 30700641 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 18 33 96 0 ENST00000403477.3:c.210-1G>A p.X70_splice ENST00000403477 NM_001204240.1 0 +TBC1D14 UCSF GRCh37 4 6925299 6925299 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 59 144 0 ENST00000409757.4:c.183C>T p.Leu61= p.L61= ENST00000409757 NM_020773.2 61 ctC/ctT 0 +TBC1D16 UCSF GRCh37 17 77984396 77984396 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 5 21 0 ENST00000310924.2:c.342G>A p.Arg114= p.R114= ENST00000310924 NM_019020.3 114 cgG/cgA 0 +TBC1D19 UCSF GRCh37 4 26585897 26585897 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 13 32 0 ENST00000264866.4:c.82C>T p.Leu28= p.L28= ENST00000264866 NM_018317.2 28 Ctg/Ttg 0 +TBC1D30 UCSF GRCh37 12 65230282 65230282 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 41 114 0 ENST00000539867.1:c.607C>T p.Leu203Phe p.L203F ENST00000539867 NM_015279.1 203 Ctt/Ttt 0 +TBC1D4 UCSF GRCh37 13 75866342 75866342 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 71 131 0 ENST00000377636.3:c.3382G>A p.Glu1128Lys p.E1128K ENST00000377636 NM_014832.2 1128 Gag/Aag 0 +TBC1D4 UCSF GRCh37 13 75894149 75894149 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 92 30 94 0 ENST00000377636.3:c.2222+1G>A p.X741_splice ENST00000377636 NM_014832.2 0 +TBC1D8 UCSF GRCh37 2 101648800 101648800 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 104 91 140 0 ENST00000376840.4:c.1821G>A p.Glu607= p.E607= ENST00000376840 607 gaG/gaA 0 +TBCCD1 UCSF GRCh37 3 186272541 186272541 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 50 96 0 ENST00000424280.1:c.1047-1G>A p.X349_splice ENST00000424280 NM_001134415.1 0 +TBCD UCSF GRCh37 17 80739489 80739489 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 88 206 0 ENST00000355528.4:c.663G>A p.Lys221= p.K221= ENST00000355528 NM_005993.4 221 aaG/aaA 0 +TBX15 UCSF GRCh37 1 119474318 119474318 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 42 110 0 ENST00000207157.3:c.25G>A p.Val9Met p.V9M ENST00000207157 NM_152380.2 9 Gtg/Atg 0 +TBX5 UCSF GRCh37 12 114804055 114804055 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 98 83 142 0 ENST00000310346.4:c.897C>T p.Gly299= p.G299= ENST00000310346 NM_000192.3 299 ggC/ggT 0 +TBXAS1 UCSF GRCh37 7 139657524 139657524 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 68 141 0 ENST00000416849.2:c.921G>A p.Arg307= p.R307= ENST00000416849 NM_001166253.1 307 agG/agA 0 +TCEAL5 UCSF GRCh37 X 102529174 102529174 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 22 123 137 0 ENST00000372680.1:c.318C>T p.Arg106= p.R106= ENST00000372680 NM_001012979.2 106 cgC/cgT 0 +TCEB3B UCSF GRCh37 18 44561448 44561448 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 32 87 0 ENST00000332567.4:c.188G>A p.Gly63Asp p.G63D ENST00000332567 NM_016427.2 63 gGc/gAc 0 +TCERG1 UCSF GRCh37 5 145838501 145838501 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 141 96 205 0 ENST00000296702.5:c.493G>A p.Val165Ile p.V165I ENST00000296702 NM_006706.3 165 Gtt/Att 0 +TCF25 UCSF GRCh37 16 89958648 89958648 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 23 46 0 ENST00000263346.8:c.662C>T p.Thr221Ile p.T221I ENST00000263346 NM_014972.2 221 aCc/aTc 0 +TCHH UCSF GRCh37 1 152084192 152084192 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 118 27 164 0 ENST00000368804.1:c.1501G>A p.Glu501Lys p.E501K ENST00000368804 NM_007113.3 501 Gag/Aag 0 +TCHH UCSF GRCh37 1 152084210 152084210 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 16 163 0 ENST00000368804.1:c.1483G>A p.Glu495Lys p.E495K ENST00000368804 NM_007113.3 495 Gag/Aag 0 +TCHH UCSF GRCh37 1 152084193 152084194 + inframe_insertion In_Frame_Ins INS - - CTGCTGCTCGCGCCTCTT NOVEL P18_Rec Untested WXS Illumina HiSeq 10 0 ENST00000368804.1:c.1499_1500insAAGAGGCGCGAGCAGCAG p.Gln500_Glu501insArgGlyAlaSerSerArg p.Q500_E501insRGASSR ENST00000368804 NM_007113.3 500 cag/caAAGAGGCGCGAGCAGCAGg 0 +TCP10L2 UCSF GRCh37 6 167592009 167592009 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 350 75 415 0 ENST00000366832.2:c.636G>A p.Arg212= p.R212= ENST00000366832 NM_001145121.1 212 cgG/cgA 0 +TCTN1 UCSF GRCh37 12 111078207 111078207 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 65 105 0 ENST00000397659.4:c.863C>T p.Ser288Phe p.S288F ENST00000397659 NM_001173975.1 288 tCc/tTc 0 +TDRD1 UCSF GRCh37 10 115991270 115991270 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 41 100 0 ENST00000251864.2:c.3564C>T p.Pro1188= p.P1188= ENST00000251864 NM_198795.1 1188 ccC/ccT 0 +TDRD9 UCSF GRCh37 14 104472730 104472730 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 174 119 284 0 ENST00000409874.4:c.1718G>A p.Gly573Glu p.G573E ENST00000409874 NM_153046.2 573 gGa/gAa 0 +TDRD9 UCSF GRCh37 14 104482389 104482389 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 58 123 0 ENST00000409874.4:c.2295G>A p.Arg765= p.R765= ENST00000409874 NM_153046.2 765 agG/agA 0 +TEC 7006 UCSF GRCh37 4 48147290 48147290 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 112 67 145 0 ENST00000381501.3:c.1276G>A p.Val426Met p.V426M ENST00000381501 NM_003215.2 426 Gtg/Atg 0 +TECTA UCSF GRCh37 11 120989349 120989349 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 105 195 0 ENST00000392793.1:c.1125C>T p.Val375= p.V375= ENST00000392793 375 gtC/gtT 0 +TECTA UCSF GRCh37 11 120996226 120996226 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 109 214 0 ENST00000392793.1:c.1419C>T p.Leu473= p.L473= ENST00000392793 473 ctC/ctT 0 +TERF1 UCSF GRCh37 8 73958219 73958219 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 147 93 206 0 ENST00000276603.5:c.1167G>A p.Lys389= p.K389= ENST00000276603 NM_017489.2 389 aaG/aaA 0 +TEX11 UCSF GRCh37 X 70080787 70080787 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 49 55 0 ENST00000395889.2:c.290-1G>A p.X97_splice ENST00000395889 NM_001003811.1 0 +TEX19 UCSF GRCh37 17 80320513 80320513 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 68 53 126 0 ENST00000333437.4:c.487C>T p.Pro163Ser p.P163S ENST00000333437 NM_207459.3 163 Cct/Tct 0 +TFAM UCSF GRCh37 10 60146021 60146021 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 122 88 182 0 ENST00000487519.1:c.143G>A p.Ser48Asn p.S48N ENST00000487519 NM_003201.2 48 aGt/aAt 0 +TFF2 UCSF GRCh37 21 43771060 43771060 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.006,1000g2011may_all_0.0182,snp132_rs7277409 P18_Rec Untested WXS Illumina HiSeq 34 37 64 0 ENST00000291526.4:c.7C>T p.Arg3Trp p.R3W ENST00000291526 NM_005423.4 3 Cgg/Tgg 0 +TFR2 UCSF GRCh37 7 100229785 100229785 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 89 56 167 0 ENST00000462107.1:c.886C>T p.Leu296Phe p.L296F ENST00000462107 296 Ctc/Ttc 0 +TGFBR2 UCSF GRCh37 3 30713734 30713734 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 122 104 208 0 ENST00000359013.4:c.1134C>T p.Ser378= p.S378= ENST00000359013 NM_001024847.2 378 tcC/tcT 0 +TGM3 UCSF GRCh37 20 2293603 2293603 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 128 118 205 0 ENST00000381458.5:c.600C>T p.Arg200= p.R200= ENST00000381458 NM_003245.3 200 cgC/cgT 0 +TH1L UCSF GRCh37 20 57564990 57564990 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 55 49 90 0 ENST00000602795.1:c.789G>A p.Gly263= p.G263= ENST00000602795 NM_198976.2 263 ggG/ggA 0 +THBS3 UCSF GRCh37 1 155170289 155170289 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 142 116 224 0 ENST00000368378.3:c.1661A>G p.Asp554Gly p.D554G ENST00000368378 NM_007112.4 554 gAt/gGt 0 +THBS3 UCSF GRCh37 1 155171292 155171292 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 67 58 90 0 ENST00000368378.3:c.1245C>T p.Ala415= p.A415= ENST00000368378 NM_007112.4 415 gcC/gcT 0 +THOC5 UCSF GRCh37 22 29916062 29916062 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 13 38 98 0 ENST00000490103.1:c.1309C>T p.Leu437= p.L437= ENST00000490103 NM_003678.4 437 Cta/Tta 0 +THSD7B UCSF GRCh37 2 138030196 138030196 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 111 237 0 ENST00000272643.3:c.2360G>A p.Arg787Lys p.R787K ENST00000272643 787 aGa/aAa 0 +THUMPD3 UCSF GRCh37 3 9408637 9408637 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 299 63 170 0 ENST00000345094.3:c.298G>A p.Glu100Lys p.E100K ENST00000345094 NM_001114092.1 100 Gag/Aag 0 +TIE1 UCSF GRCh37 1 43772556 43772556 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 57 113 0 ENST00000372476.3:c.530G>A p.Arg177Gln p.R177Q ENST00000372476 NM_005424.4 177 cGg/cAg 0 +TIGIT UCSF GRCh37 3 114026946 114026946 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 168 105 271 0 ENST00000486257.1:c.703G>A p.Gly235Ser p.G235S ENST00000486257 235 Ggt/Agt 0 +TIMM50 UCSF GRCh37 19 39971203 39971203 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 61 134 0 ENST00000314349.4:c.19C>T p.Leu7= p.L7= ENST00000314349 NM_001001563.1 7 Ctg/Ttg 0 +TIMP1 UCSF GRCh37 X 47442895 47442895 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 11 70 68 0 ENST00000218388.4:c.81C>T p.Val27= p.V27= ENST00000218388 NM_003254.2 27 gtC/gtT 0 +TINAG UCSF GRCh37 6 54173386 54173386 + missense_variant Missense_Mutation SNP T T G NOVEL P18_Rec Untested WXS Illumina HiSeq 58 29 73 0 ENST00000259782.4:c.38T>G p.Leu13Arg p.L13R ENST00000259782 NM_014464.3 13 cTt/cGt 0 +TINAGL1 UCSF GRCh37 1 32050857 32050857 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 97 164 0 ENST00000271064.7:c.963C>T p.Arg321= p.R321= ENST00000271064 NM_022164.2 321 cgC/cgT 0 +TJP3 UCSF GRCh37 19 3738640 3738640 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 64 44 79 0 ENST00000589378.1:c.1399G>C p.Val467Leu p.V467L ENST00000589378 NM_001267561.1 467 Gtg/Ctg 0 +TKT UCSF GRCh37 3 53265544 53265544 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 43 107 0 ENST00000423516.1:c.795G>A p.Trp265Ter p.W265* ENST00000423516 NM_001258028.1 265 tgG/tgA 0 +TLE3 UCSF GRCh37 15 70347554 70347554 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 63 127 0 ENST00000558939.1:c.1421C>T p.Pro474Leu p.P474L ENST00000558939 NM_001282979.1 474 cCg/cTg 0 +TLE6 UCSF GRCh37 19 2989107 2989107 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 65 47 124 0 ENST00000246112.4:c.789C>T p.Ala263= p.A263= ENST00000246112 NM_001143986.1 263 gcC/gcT 0 +TLN2 UCSF GRCh37 15 63125806 63125806 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 23 70 178 0 ENST00000561311.1:c.7106G>A p.Arg2369Lys p.R2369K ENST00000561311 2369 aGg/aAg 0 +TM9SF4 UCSF GRCh37 20 30737484 30737484 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 53 50 63 0 ENST00000398022.2:c.1002C>T p.Val334= p.V334= ENST00000398022 NM_014742.3 334 gtC/gtT 0 +TMBIM4 UCSF GRCh37 12 66539731 66539731 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 55 135 0 ENST00000358230.3:c.354C>T p.Phe118= p.F118= ENST00000358230 NM_016056.2 118 ttC/ttT 0 +TMC8 UCSF GRCh37 17 76134223 76134223 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 50 105 0 ENST00000318430.5:c.1487C>T p.Pro496Leu p.P496L ENST00000318430 NM_152468.4 496 cCc/cTc 0 +TMEM109 UCSF GRCh37 11 60687263 60687263 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 136 112 202 0 ENST00000227525.3:c.98C>T p.Ala33Val p.A33V ENST00000227525 NM_024092.2 33 gCc/gTc 0 +TMEM115 UCSF GRCh37 3 50395655 50395655 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.00097 P18_Rec Untested WXS Illumina HiSeq 111 89 165 0 ENST00000266025.3:c.840C>T p.Ala280= p.A280= ENST00000266025 NM_007024.4 280 gcC/gcT 0 +TMEM131 UCSF GRCh37 2 98409175 98409175 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 68 158 0 ENST00000186436.5:c.3818G>A p.Gly1273Asp p.G1273D ENST00000186436 NM_015348.1 1273 gGt/gAt 0 +TMEM132A UCSF GRCh37 11 60694802 60694802 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 54 135 0 ENST00000005286.4:c.227C>T p.Ser76Phe p.S76F ENST00000005286 NM_178031.2 76 tCc/tTc 0 +TMEM132C UCSF GRCh37 12 129178440 129178440 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 68 159 0 ENST00000435159.2:c.1516G>A p.Val506Met p.V506M ENST00000435159 NM_001136103.2 506 Gtg/Atg 0 +TMEM143 UCSF GRCh37 19 48845943 48845943 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 41 37 76 0 ENST00000293261.3:c.819G>A p.Thr273= p.T273= ENST00000293261 NM_018273.2 273 acG/acA 0 +TMEM151B UCSF GRCh37 6 44243428 44243428 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 10 4 17 0 ENST00000451188.2:c.865G>A p.Asp289Asn p.D289N ENST00000451188 NM_001137560.1 289 Gac/Aac 0 +TMEM164 UCSF GRCh37 X 109247135 109247135 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 82 93 0 ENST00000372073.1:c.133G>A p.Val45Ile p.V45I ENST00000372073 45 Gtc/Atc 0 +TMEM165 UCSF GRCh37 4 56290810 56290810 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 40 97 0 ENST00000381334.5:c.898G>A p.Val300Met p.V300M ENST00000381334 NM_018475.4 300 Gtg/Atg 0 +TMEM173 UCSF GRCh37 5 138858022 138858022 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 111 111 246 0 ENST00000330794.4:c.592C>T p.Leu198= p.L198= ENST00000330794 NM_198282.2 198 Ctg/Ttg 0 +TMEM176A UCSF GRCh37 7 150501561 150501561 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 51 121 0 ENST00000484928.1:c.666+1G>A p.X222_splice ENST00000484928 0 +TMEM177 UCSF GRCh37 2 120439314 120439314 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 92 45 156 0 ENST00000424086.1:c.885G>A p.Arg295= p.R295= ENST00000424086 NM_001105198.1 295 cgG/cgA 0 +TMEM181 UCSF GRCh37 6 158957729 158957729 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 9 19 0 ENST00000367090.3:c.251G>A p.Gly84Asp p.G84D ENST00000367090 NM_020823.1 84 gGt/gAt 0 +TMEM207 UCSF GRCh37 3 190167548 190167548 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 66 139 0 ENST00000354905.2:c.51G>A p.Gly17= p.G17= ENST00000354905 NM_207316.1 17 ggG/ggA 0 +TMEM209 UCSF GRCh37 7 129841783 129841783 + synonymous_variant Silent SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 240 99 216 0 ENST00000397622.2:c.480T>C p.Thr160= p.T160= ENST00000397622 NM_032842.3 160 acT/acC 0 +TMEM214 UCSF GRCh37 2 27258058 27258058 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 51 99 0 ENST00000238788.9:c.407G>A p.Gly136Glu p.G136E ENST00000238788 NM_017727.4 136 gGa/gAa 0 +TMEM38A UCSF GRCh37 19 16791263 16791263 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 199 139 310 0 ENST00000187762.2:c.337C>T p.Pro113Ser p.P113S ENST00000187762 NM_024074.1 113 Cct/Tct 0 +TMEM39A UCSF GRCh37 3 119156784 119156784 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 85 59 141 0 ENST00000319172.5:c.742C>T p.Leu248= p.L248= ENST00000319172 NM_018266.2 248 Cta/Tta 0 +TMEM44 UCSF GRCh37 3 194343978 194343978 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 66 40 102 0 ENST00000392432.2:c.587C>T p.Ser196Phe p.S196F ENST00000392432 NM_001166305.1 196 tCt/tTt 0 +TMEM63B UCSF GRCh37 6 44117599 44117599 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 16 21 0 ENST00000259746.9:c.1417C>T p.Pro473Ser p.P473S ENST00000259746 473 Ccc/Tcc 0 +TMEM63C UCSF GRCh37 14 77705765 77705765 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 37 70 0 ENST00000298351.4:c.736C>T p.Pro246Ser p.P246S ENST00000298351 NM_020431.2 246 Cca/Tca 0 +TMEM85 UCSF GRCh37 15 34520724 34520724 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 213 152 310 0 ENST00000267750.4:c.450G>A p.Lys150= p.K150= ENST00000267750 NM_016454.2 150 aaG/aaA 0 +TMF1 UCSF GRCh37 3 69092917 69092917 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 70 135 0 ENST00000398559.2:c.1562G>A p.Arg521Lys p.R521K ENST00000398559 521 aGa/aAa 0 +TMPRSS11A UCSF GRCh37 4 68795751 68795751 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 113 77 189 0 ENST00000334830.7:c.337G>A p.Glu113Lys p.E113K ENST00000334830 113 Gaa/Aaa 0 +TMPRSS11D UCSF GRCh37 4 68688127 68688127 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 127 92 226 0 ENST00000283916.6:c.1185G>A p.Leu395= p.L395= ENST00000283916 NM_004262.2 395 ctG/ctA 0 +TMPRSS13 UCSF GRCh37 11 117784494 117784494 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 84 55 119 0 ENST00000524993.1:c.807G>A p.Glu269= p.E269= ENST00000524993 NM_001077263.2 269 gaG/gaA 0 +TMPRSS15 UCSF GRCh37 21 19732166 19732166 + missense_variant Missense_Mutation SNP A A T NOVEL P18_Rec Untested WXS Illumina HiSeq 125 85 154 0 ENST00000284885.3:c.788T>A p.Leu263His p.L263H ENST00000284885 NM_002772.2 263 cTt/cAt 0 +TMPRSS3 UCSF GRCh37 21 43796669 43796669 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 61 53 98 0 ENST00000291532.3:c.1175G>A p.Gly392Asp p.G392D ENST00000291532 NM_032404.2 392 gGt/gAt 0 +TNFAIP1 UCSF GRCh37 17 26669339 26669339 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 42 34 80 0 ENST00000226225.2:c.585C>T p.Gly195= p.G195= ENST00000226225 NM_021137.4 195 ggC/ggT 0 +TNFAIP8L3 UCSF GRCh37 15 51350625 51350625 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 33 80 0 ENST00000327536.5:c.332G>A p.Ser111Asn p.S111N ENST00000327536 NM_207381.2 111 aGt/aAt 0 +TNFRSF10B UCSF GRCh37 8 22926275 22926275 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 14 22 0 ENST00000276431.4:c.133G>A p.Val45Ile p.V45I ENST00000276431 NM_147187.2 45 Gtc/Atc 0 +TNFRSF13C UCSF GRCh37 22 42322114 42322114 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 13 30 0 ENST00000291232.3:c.358G>A p.Asp120Asn p.D120N ENST00000291232 NM_052945.3 120 Gac/Aac 0 +TNFRSF4 UCSF GRCh37 1 1147450 1147450 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 15 9 18 0 ENST00000379236.3:c.506G>A p.Arg169Lys p.R169K ENST00000379236 NM_003327.3 169 aGg/aAg 0 +TNK1 UCSF GRCh37 17 7290413 7290413 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 31 49 0 ENST00000576812.1:c.1352C>T p.Thr451Ile p.T451I ENST00000576812 NM_001251902.1 451 aCc/aTc 0 +TNK2 UCSF GRCh37 3 195608963 195608963 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 48 120 0 ENST00000381916.2:c.1035C>T p.Asp345= p.D345= ENST00000381916 NM_001010938.1 345 gaC/gaT 0 +TNNI1 UCSF GRCh37 1 201383683 201383683 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 16 33 0 ENST00000361379.4:c.152C>T p.Thr51Met p.T51M ENST00000361379 NM_003281.3 51 aCg/aTg 0 +TNNI3 UCSF GRCh37 19 55665468 55665468 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 85 69 129 0 ENST00000344887.5:c.479G>A p.Gly160Glu p.G160E ENST00000344887 NM_000363.4 160 gGg/gAg 0 +TNRC18 UCSF GRCh37 7 5353477 5353477 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 28 52 0 ENST00000430969.1:c.7045G>A p.Glu2349Lys p.E2349K ENST00000430969 NM_001080495.2 2349 Gag/Aag 0 +TNRC18 UCSF GRCh37 7 5410939 5410939 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 12 26 0 ENST00000430969.1:c.3286C>T p.Pro1096Ser p.P1096S ENST00000430969 NM_001080495.2 1096 Cct/Tct 0 +TNXB UCSF GRCh37 6 32065707 32065707 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 55 53 105 0 ENST00000375244.3:c.269G>A p.Gly90Asp p.G90D ENST00000375244 90 gGc/gAc 0 +TOB1 UCSF GRCh37 17 48941018 48941018 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 109 71 171 0 ENST00000499247.2:c.361G>A p.Gly121Arg p.G121R ENST00000499247 NM_005749.3 121 Gga/Aga 0 +TOM1 UCSF GRCh37 22 35713897 35713897 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 62 133 0 ENST00000411850.1:c.80G>A p.Ser27Asn p.S27N ENST00000411850 NM_001135732.1 27 aGc/aAc 0 +TONSL UCSF GRCh37 8 145659615 145659615 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 8 9 23 0 ENST00000409379.3:c.3133C>T p.Leu1045Phe p.L1045F ENST00000409379 NM_013432.4 1045 Ctc/Ttc 0 +TOP1 UCSF GRCh37 20 39741529 39741529 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 55 126 0 ENST00000361337.2:c.1416C>T p.Val472= p.V472= ENST00000361337 NM_003286.2 472 gtC/gtT 0 +TOP2A UCSF GRCh37 17 38563110 38563110 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 128 231 0 ENST00000423485.1:c.1711G>A p.Glu571Lys p.E571K ENST00000423485 NM_001067.3 571 Gag/Aag 0 +TOP2B UCSF GRCh37 3 25670612 25670612 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 179 115 250 0 ENST00000435706.2:c.1699G>A p.Gly567Ser p.G567S ENST00000435706 NM_001068.3 567 Ggc/Agc 0 +TOR1AIP2 UCSF GRCh37 1 179820072 179820072 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 79 200 0 ENST00000367612.3:c.461C>T p.Pro154Leu p.P154L ENST00000367612 NM_145034.4 154 cCt/cTt 0 +TOR1B UCSF GRCh37 9 132571237 132571237 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 67 161 0 ENST00000259339.2:c.695G>A p.Gly232Glu p.G232E ENST00000259339 NM_014506.1 232 gGa/gAa 0 +TOR2A UCSF GRCh37 9 130495599 130495599 + intron_variant Intron SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 57 133 0 ENST00000373284.5:c.593+65C>T *198* ENST00000373284 NM_001085347.2 0 +TP53 UCSF GRCh37 17 7578242 7578242 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 69 41 111 0 ENST00000269305.4:c.607G>A p.Val203Met p.V203M ENST00000269305 NM_001126112.2 203 Gtg/Atg 0 +TP53 UCSF GRCh37 17 7577572 7577572 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 18 61 78 0 ENST00000269305.4:c.709A>G p.Met237Val p.M237V ENST00000269305 NM_001126112.2 237 Atg/Gtg 0 +TPR UCSF GRCh37 1 186287932 186287932 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 74 190 0 ENST00000367478.4:c.6597C>T p.Phe2199= p.F2199= ENST00000367478 NM_003292.2 2199 ttC/ttT 0 +TRAF3IP1 UCSF GRCh37 2 239242654 239242654 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 31 69 0 ENST00000373327.4:c.1041G>A p.Arg347= p.R347= ENST00000373327 NM_015650.3 347 cgG/cgA 0 +TRAF3IP3 UCSF GRCh37 1 209936207 209936207 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 71 196 0 ENST00000367024.1:c.543G>A p.Gln181= p.Q181= ENST00000367024 181 caG/caA 0 +TRAFD1 UCSF GRCh37 12 112585941 112585941 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 60 112 0 ENST00000257604.5:c.991G>A p.Val331Met p.V331M ENST00000257604 NM_001143906.1 331 Gtg/Atg 0 +TRANK1 UCSF GRCh37 3 36896976 36896976 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 198 148 338 0 ENST00000429976.2:c.4105G>A p.Val1369Ile p.V1369I ENST00000429976 1369 Gtt/Att 0 +TRAPPC10 UCSF GRCh37 21 45506703 45506703 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 74 156 0 ENST00000291574.4:c.2401C>T p.Pro801Ser p.P801S ENST00000291574 NM_003274.4 801 Cct/Tct 0 +TREX1 UCSF GRCh37 3 48508814 48508814 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 79 81 157 0 ENST00000422277.2:c.925C>T p.Leu309= p.L309= ENST00000422277 NM_016381.4 309 Ctg/Ttg 0 +TRIM29 UCSF GRCh37 11 120008683 120008683 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 36 23 70 0 ENST00000341846.5:c.57C>T p.Ala19= p.A19= ENST00000341846 NM_012101.3 19 gcC/gcT 0 +TRIM33 UCSF GRCh37 1 114940462 114940462 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 167 135 246 0 ENST00000358465.2:c.3192G>A p.Gln1064= p.Q1064= ENST00000358465 NM_015906.3 1064 caG/caA 0 +TRIM43B UCSF GRCh37 2 96147415 96147415 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 51 162 0 ENST00000454263.2:n.565G>A *189* ENST00000454263 0 +TRIM45 UCSF GRCh37 1 117663495 117663495 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 66 112 0 ENST00000256649.4:c.329C>T p.Ala110Val p.A110V ENST00000256649 NM_025188.3 110 gCt/gTt 0 +TRIM47 UCSF GRCh37 17 73872525 73872525 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 22 15 40 0 ENST00000254816.2:c.820G>A p.Ala274Thr p.A274T ENST00000254816 NM_033452.2 274 Gct/Act 0 +TRIM50 UCSF GRCh37 7 72738554 72738554 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 61 58 123 0 ENST00000333149.2:c.232C>T p.Leu78= p.L78= ENST00000333149 NM_001281450.1 78 Ctg/Ttg 0 +TRIM52 UCSF GRCh37 5 180687399 180687399 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 159 107 224 0 ENST00000327767.4:c.416T>G p.Leu139Trp p.L139W ENST00000327767 NM_032765.2 139 tTg/tGg 0 +TRIM52 UCSF GRCh37 5 180687407 180687407 + synonymous_variant Silent SNP T T G NOVEL P18_Rec Untested WXS Illumina HiSeq 147 106 231 0 ENST00000327767.4:c.408A>C p.Leu136= p.L136= ENST00000327767 NM_032765.2 136 ctA/ctC 0 +TRIM55 UCSF GRCh37 8 67086798 67086798 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 179 112 235 0 ENST00000315962.4:c.1617C>T p.Ser539= p.S539= ENST00000315962 NM_184085.1 539 tcC/tcT 0 +TRIM71 UCSF GRCh37 3 32933098 32933098 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 81 145 0 ENST00000383763.5:c.2402C>T p.Ala801Val p.A801V ENST00000383763 NM_001039111.1 801 gCt/gTt 0 +TRIM71 UCSF GRCh37 3 32932469 32932469 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 45 95 0 ENST00000383763.5:c.1773C>T p.Leu591= p.L591= ENST00000383763 NM_001039111.1 591 ctC/ctT 0 +TRIM77P UCSF GRCh37 11 89443679 89443679 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 90 211 0 ENST00000398290.3:c.213G>A p.Glu71= p.E71= ENST00000398290 NM_001146162.1 71 gaG/gaA 0 +TRIM9 UCSF GRCh37 14 51446261 51446261 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 166 105 231 0 ENST00000298355.3:c.1914G>A p.Glu638= p.E638= ENST00000298355 NM_015163.5 638 gaG/gaA 0 +TRIM9 UCSF GRCh37 14 51448685 51448685 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 84 144 0 ENST00000298355.3:c.1740C>T p.Tyr580= p.Y580= ENST00000298355 NM_015163.5 580 taC/taT 0 +TRIO UCSF GRCh37 5 14368834 14368834 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 81 162 0 ENST00000344204.4:c.2892G>A p.Ala964= p.A964= ENST00000344204 NM_007118.2 964 gcG/gcA 0 +TRIP11 UCSF GRCh37 14 92482083 92482083 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 66 154 0 ENST00000267622.4:c.780C>T p.Asp260= p.D260= ENST00000267622 NM_004239.3 260 gaC/gaT 0 +TRMT5 UCSF GRCh37 14 61441857 61441857 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0014 P18_Rec Untested WXS Illumina HiSeq 71 49 98 0 ENST00000261249.6:c.1500C>T p.Asp500= p.D500= ENST00000261249 NM_020810.2 500 gaC/gaT 0 +TRPA1 UCSF GRCh37 8 72968057 72968057 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 64 116 0 ENST00000262209.4:c.1228G>A p.Asp410Asn p.D410N ENST00000262209 NM_007332.2 410 Gac/Aac 0 +TRPC4AP UCSF GRCh37 20 33600840 33600840 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 121 74 184 0 ENST00000252015.2:c.1380G>A p.Arg460= p.R460= ENST00000252015 460 agG/agA 0 +TRPM2 UCSF GRCh37 21 45859007 45859007 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 45 36 72 0 ENST00000397928.1:c.4225G>A p.Glu1409Lys p.E1409K ENST00000397928 NM_003307.3 1409 Gag/Aag 0 +TRPM5 UCSF GRCh37 11 2441483 2441483 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 40 77 0 ENST00000155858.6:c.618G>A p.Lys206= p.K206= ENST00000155858 NM_014555.3 206 aaG/aaA 0 +TRPM6 UCSF GRCh37 9 77397347 77397347 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 94 85 176 0 ENST00000360774.1:c.3140C>T p.Pro1047Leu p.P1047L ENST00000360774 NM_017662.4 1047 cCa/cTa 0 +TRPS1 UCSF GRCh37 8 116616617 116616617 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 161 109 235 0 ENST00000395715.3:c.1579G>A p.Gly527Arg p.G527R ENST00000395715 NM_014112.2 527 Gga/Aga 0 +TRPV2 UCSF GRCh37 17 16330800 16330800 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 96 64 113 0 ENST00000338560.7:c.1289C>T p.Ser430Phe p.S430F ENST00000338560 NM_016113.4 430 tCc/tTc 0 +TRPV2 UCSF GRCh37 17 16330170 16330170 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 76 59 127 0 ENST00000338560.7:c.1230C>T p.Tyr410= p.Y410= ENST00000338560 NM_016113.4 410 taC/taT 0 +TRRAP UCSF GRCh37 7 98581887 98581887 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 368 118 397 0 ENST00000359863.4:c.9206C>T p.Thr3069Ile p.T3069I ENST00000359863 NM_001244580.1 3069 aCt/aTt 0 +TSC1 UCSF GRCh37 9 135772893 135772893 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 182 125 287 0 ENST00000298552.3:c.2730G>A p.Leu910= p.L910= ENST00000298552 NM_001162426.1 910 ttG/ttA 0 +TSEN2 UCSF GRCh37 3 12544891 12544891 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 110 88 179 0 ENST00000284995.6:c.439G>A p.Ala147Thr p.A147T ENST00000284995 NM_025265.3 147 Gct/Act 0 +TSHZ3 UCSF GRCh37 19 31768396 31768396 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 48 109 0 ENST00000240587.4:c.2303C>T p.Pro768Leu p.P768L ENST00000240587 NM_020856.2 768 cCc/cTc 0 +TSN UCSF GRCh37 2 122519079 122519079 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 197 154 307 0 ENST00000389682.3:c.352G>A p.Ala118Thr p.A118T ENST00000389682 NM_004622.2 118 Gca/Aca 0 +TSN UCSF GRCh37 2 122514836 122514836 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 50 122 0 ENST00000389682.3:c.87G>A p.Gln29= p.Q29= ENST00000389682 NM_004622.2 29 caG/caA 0 +TSPAN32 UCSF GRCh37 11 2325364 2325364 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 7 19 31 0 ENST00000182290.4:c.209G>A p.Gly70Asp p.G70D ENST00000182290 NM_139022.2 70 gGc/gAc 0 +TSPAN5 UCSF GRCh37 4 99579356 99579356 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 115 70 171 0 ENST00000305798.3:c.22G>A p.Gly8Ser p.G8S ENST00000305798 NM_005723.3 8 Ggt/Agt 0 +TSPYL2 UCSF GRCh37 X 53112481 53112481 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 47 54 0 ENST00000375442.4:c.801C>T p.Val267= p.V267= ENST00000375442 NM_022117.3 267 gtC/gtT 0 +TSSK4 UCSF GRCh37 14 24676709 24676709 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 44 119 0 ENST00000339917.5:c.828G>A p.Glu276= p.E276= ENST00000339917 NM_001184739.1 276 gaG/gaA 0 +TTBK1 UCSF GRCh37 6 43250801 43250801 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 11 7 18 0 ENST00000259750.4:c.2323G>A p.Ala775Thr p.A775T ENST00000259750 NM_032538.1 775 Gca/Aca 0 +TTC38 UCSF GRCh37 22 46668245 46668245 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 51 133 0 ENST00000381031.3:c.125C>T p.Thr42Ile p.T42I ENST00000381031 NM_017931.2 42 aCc/aTc 0 +TTC38 UCSF GRCh37 22 46669910 46669910 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 66 129 0 ENST00000381031.3:c.309G>A p.Gln103= p.Q103= ENST00000381031 NM_017931.2 103 caG/caA 0 +TTC39A UCSF GRCh37 1 51760071 51760071 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 81 76 109 0 ENST00000413473.2:c.1270C>T p.Pro424Ser p.P424S ENST00000413473 NM_001144832.1 424 Cct/Tct 0 +TTC39C UCSF GRCh37 18 21660666 21660666 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 86 67 149 0 ENST00000317571.3:c.578C>T p.Thr193Ile p.T193I ENST00000317571 NM_001135993.1 193 aCt/aTt 0 +TTC7B UCSF GRCh37 14 91142910 91142910 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 91 207 0 ENST00000328459.6:c.1109C>T p.Thr370Ile p.T370I ENST00000328459 NM_001010854.1 370 aCc/aTc 0 +TTF2 UCSF GRCh37 1 117618096 117618096 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 99 65 197 0 ENST00000369466.4:c.890A>G p.Asp297Gly p.D297G ENST00000369466 NM_003594.3 297 gAt/gGt 0 +TTI1 UCSF GRCh37 20 36641885 36641885 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 103 235 0 ENST00000373448.2:c.334C>T p.Pro112Ser p.P112S ENST00000373448 NM_014657.1 112 Cct/Tct 0 +TTLL2 UCSF GRCh37 6 167755101 167755101 + synonymous_variant Silent SNP G G A NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 87 65 148 0 ENST00000239587.5:c.1713G>A p.Arg571= p.R571= ENST00000239587 NM_031949.4 571 agG/agA 0 +TTLL4 UCSF GRCh37 2 219603311 219603311 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 105 184 0 ENST00000392102.1:c.912G>A p.Trp304Ter p.W304* ENST00000392102 NM_014640.4 304 tgG/tgA 0 +TTLL5 UCSF GRCh37 14 76211907 76211907 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 87 51 125 0 ENST00000298832.9:c.1470G>A p.Glu490= p.E490= ENST00000298832 NM_015072.4 490 gaG/gaA 0 +TTN UCSF GRCh37 2 179429104 179429104 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 160 107 256 0 ENST00000589042.1:c.81755G>A p.Gly27252Glu p.G27252E ENST00000589042 NM_001267550.1 27252 gGa/gAa 0 +TTN UCSF GRCh37 2 179425139 179425139 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 214 189 343 0 ENST00000589042.1:c.85720C>T p.Pro28574Ser p.P28574S ENST00000589042 NM_001267550.1 28574 Ccc/Tcc 0 +TTN UCSF GRCh37 2 179500188 179500188 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 163 95 222 0 ENST00000589042.1:c.41863C>T p.Pro13955Ser p.P13955S ENST00000589042 NM_001267550.1 13955 Cct/Tct 0 +TTN UCSF GRCh37 2 179642652 179642652 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 62 47 108 0 ENST00000589042.1:c.4259C>T p.Ala1420Val p.A1420V ENST00000589042 NM_001267550.1 1420 gCa/gTa 0 +TTN UCSF GRCh37 2 179429433 179429433 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 129 106 194 0 ENST00000589042.1:c.81426G>A p.Glu27142= p.E27142= ENST00000589042 NM_001267550.1 27142 gaG/gaA 0 +TUBAL3 UCSF GRCh37 10 5436157 5436157 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 189 70 144 0 ENST00000380419.3:c.664C>T p.Arg222Cys p.R222C ENST00000380419 NM_024803.2 222 Cgt/Tgt 0 +TUBAL3 UCSF GRCh37 10 5435827 5435827 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.00094 P18_Rec Untested WXS Illumina HiSeq 146 96 153 0 ENST00000380419.3:c.994C>T p.Pro332Ser p.P332S ENST00000380419 NM_024803.2 332 Ccc/Tcc 0 +TUBB UCSF GRCh37 6 30691620 30691620 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 129 102 220 0 ENST00000327892.8:c.781C>T p.Pro261Ser p.P261S ENST00000327892 NM_178014.2 261 Cca/Tca 0 +TUBB6 UCSF GRCh37 18 12308752 12308752 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 70 54 108 0 ENST00000317702.5:c.124C>T p.Leu42= p.L42= ENST00000317702 42 Ctg/Ttg 0 +TUFM UCSF GRCh37 16 28856684 28856684 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 211 84 204 0 ENST00000313511.3:c.365C>T p.Ala122Val p.A122V ENST00000313511 NM_003321.4 122 gCc/gTc 0 +TWF2 UCSF GRCh37 3 52269091 52269091 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 37 67 0 ENST00000305533.5:c.57G>A p.Lys19= p.K19= ENST00000305533 NM_007284.3 19 aaG/aaA 0 +TXLNG UCSF GRCh37 X 16859664 16859664 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 75 79 0 ENST00000380122.5:c.1362C>T p.Val454= p.V454= ENST00000380122 NM_018360.2 454 gtC/gtT 0 +TXNL4B UCSF GRCh37 16 72124636 72124636 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 124 101 198 0 ENST00000268483.3:c.13C>T p.Leu5= p.L5= ENST00000268483 NM_017853.2 5 Ctg/Ttg 0 +TXNRD1 UCSF GRCh37 12 104712817 104712817 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 191 155 290 0 ENST00000525566.1:c.857G>A p.Gly286Asp p.G286D ENST00000525566 NM_001093771.2 286 gGt/gAt 0 +TYK2 UCSF GRCh37 19 10475430 10475430 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 57 114 0 ENST00000525621.1:c.1227C>T p.Ser409= p.S409= ENST00000525621 NM_003331.4 409 tcC/tcT 0 +TYW1B UCSF GRCh37 7 72267497 72267497 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 191 144 289 0 ENST00000438904.2:c.764G>A p.Gly255Asp p.G255D ENST00000438904 255 gGt/gAt 0 +UBA6 UCSF GRCh37 4 68530983 68530983 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 87 59 179 0 ENST00000322244.5:c.821G>A p.Gly274Asp p.G274D ENST00000322244 NM_018227.5 274 gGt/gAt 0 +UBE2F UCSF GRCh37 2 238881803 238881803 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 152 100 234 0 ENST00000272930.4:c.54G>A p.Arg18= p.R18= ENST00000272930 NM_001278308.1 18 cgG/cgA 0 +UBE2O UCSF GRCh37 17 74397137 74397137 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 36 77 0 ENST00000319380.7:c.849G>A p.Lys283= p.K283= ENST00000319380 NM_022066.3 283 aaG/aaA 0 +UBE4B UCSF GRCh37 1 10186901 10186901 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 68 173 0 ENST00000343090.6:c.1604C>T p.Ser535Phe p.S535F ENST00000343090 NM_001105562.2 535 tCc/tTc 0 +UBQLN1 UCSF GRCh37 9 86294846 86294846 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 185 137 280 0 ENST00000376395.4:c.555G>A p.Met185Ile p.M185I ENST00000376395 NM_053067.2 185 atG/atA 0 +UBR3 UCSF GRCh37 2 170734087 170734087 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 77 173 0 ENST00000418381.1:c.928G>A p.Asp310Asn p.D310N ENST00000418381 NM_172070.3 310 Gat/Aat 0 +UBR3 UCSF GRCh37 2 170912076 170912076 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 60 102 0 ENST00000418381.1:c.4767C>T p.His1589= p.H1589= ENST00000418381 NM_172070.3 1589 caC/caT 0 +UBR4 UCSF GRCh37 1 19453150 19453150 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 42 86 0 ENST00000375254.3:c.9229-1G>A p.X3077_splice ENST00000375254 NM_020765.2 0 +UBR5 UCSF GRCh37 8 103283366 103283366 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 81 70 125 0 ENST00000520539.1:c.7081G>A p.Asp2361Asn p.D2361N ENST00000520539 NM_015902.5 2361 Gat/Aat 0 +UBTF UCSF GRCh37 17 42288315 42288315 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 25 74 0 ENST00000302904.4:c.1204G>A p.Gly402Ser p.G402S ENST00000302904 402 Ggc/Agc 0 +UCN3 UCSF GRCh37 10 5415867 5415867 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 62 35 43 0 ENST00000380433.3:c.184C>T p.Leu62= p.L62= ENST00000380433 NM_053049.2 62 Ctg/Ttg 0 +UGT2A3 UCSF GRCh37 4 69817062 69817062 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 105 63 170 0 ENST00000251566.4:c.417G>A p.Gln139= p.Q139= ENST00000251566 NM_024743.3 139 caG/caA 0 +UGT2B7 UCSF GRCh37 4 69964261 69964261 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 173 111 283 0 ENST00000305231.7:c.725G>A p.Arg242Lys p.R242K ENST00000305231 NM_001074.2 242 aGa/aAa 0 +UGT3A1 UCSF GRCh37 5 35965937 35965937 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 98 63 166 0 ENST00000274278.3:c.394G>A p.Asp132Asn p.D132N ENST00000274278 NM_152404.3 132 Gat/Aat 0 +UGT3A2 UCSF GRCh37 5 36035916 36035916 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 48 39 102 1 ENST00000282507.3:c.1456C>T p.Leu486Phe p.L486F ENST00000282507 NM_174914.3 486 Ctc/Ttc 0 +UGT3A2 UCSF GRCh37 5 36038081 36038081 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 64 165 0 ENST00000282507.3:c.1113G>A p.Gly371= p.G371= ENST00000282507 NM_174914.3 371 ggG/ggA 0 +UHRF1BP1L UCSF GRCh37 12 100453025 100453025 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 115 92 180 0 ENST00000279907.7:c.2030C>T p.Thr677Ile p.T677I ENST00000279907 NM_015054.1 677 aCt/aTt 0 +ULK2 UCSF GRCh37 17 19700973 19700973 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 39 72 0 ENST00000395544.4:c.1545G>A p.Gln515= p.Q515= ENST00000395544 NM_014683.3 515 caG/caA 0 +UNC45A UCSF GRCh37 15 91486148 91486148 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 127 89 221 0 ENST00000418476.2:c.863C>T p.Ala288Val p.A288V ENST00000418476 NM_018671.3 288 gCc/gTc 0 +UNC5C UCSF GRCh37 4 96104058 96104058 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 130 90 199 0 ENST00000453304.1:c.2441C>T p.Thr814Ile p.T814I ENST00000453304 NM_003728.3 814 aCc/aTc 0 +UPF2 UCSF GRCh37 10 12021094 12021094 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 241 79 195 0 ENST00000356352.2:c.1915G>A p.Asp639Asn p.D639N ENST00000356352 639 Gat/Aat 0 +UPF2 UCSF GRCh37 10 12077080 12077080 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 282 166 267 0 ENST00000356352.2:c.343G>A p.Glu115Lys p.E115K ENST00000356352 115 Gaa/Aaa 0 +URB1 UCSF GRCh37 21 33755740 33755740 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 40 31 71 0 ENST00000382751.3:c.558G>A p.Arg186= p.R186= ENST00000382751 NM_014825.2 186 agG/agA 0 +URGCP UCSF GRCh37 7 43917741 43917741 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 123 105 213 0 ENST00000453200.1:c.1321G>A p.Ala441Thr p.A441T ENST00000453200 441 Gca/Aca 0 +USH2A UCSF GRCh37 1 216420210 216420210 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 129 223 0 ENST00000307340.3:c.2526C>T p.Phe842= p.F842= ENST00000307340 NM_206933.2 842 ttC/ttT 0 +USHBP1 UCSF GRCh37 19 17370229 17370229 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 107 68 151 0 ENST00000252597.3:c.915G>A p.Glu305= p.E305= ENST00000252597 NM_031941.3 305 gaG/gaA 0 +USP18 UCSF GRCh37 22 18650764 18650764 + synonymous_variant Silent SNP T T A NOVEL P18_Rec Untested WXS Illumina HiSeq 27 106 258 0 ENST00000215794.7:c.588T>A p.Leu196= p.L196= ENST00000215794 NM_017414.3 196 ctT/ctA 0 +USP19 UCSF GRCh37 3 49154746 49154746 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 38 27 78 0 ENST00000434032.2:c.655G>A p.Glu219Lys p.E219K ENST00000434032 NM_001199160.1 219 Gag/Aag 0 +USP20 UCSF GRCh37 9 132635984 132635984 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 71 50 128 0 ENST00000315480.4:c.1701G>A p.Arg567= p.R567= ENST00000315480 567 cgG/cgA 0 +USP32 UCSF GRCh37 17 58303402 58303402 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 91 197 0 ENST00000300896.4:c.1430G>A p.Ser477Asn p.S477N ENST00000300896 NM_032582.3 477 aGc/aAc 0 +USP34 UCSF GRCh37 2 61597500 61597500 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 114 25 244 0 ENST00000398571.2:c.1207C>T p.Arg403Ter p.R403* ENST00000398571 NM_014709.3 403 Cga/Tga 0 +USP36 UCSF GRCh37 17 76816091 76816091 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 63 192 0 ENST00000542802.3:c.832G>A p.Ala278Thr p.A278T ENST00000542802 278 Gct/Act 0 +USP42 UCSF GRCh37 7 6196395 6196395 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 34 148 0 ENST00000306177.5:c.3652G>A p.Asp1218Asn p.D1218N ENST00000306177 NM_032172.2 1218 Gac/Aac 0 +USP43 UCSF GRCh37 17 9580186 9580186 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 56 109 0 ENST00000285199.7:c.957C>T p.Val319= p.V319= ENST00000285199 NM_001267576.1 319 gtC/gtT 0 +USP43 UCSF GRCh37 17 9631548 9631548 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 102 52 162 0 ENST00000285199.7:c.2613C>T p.Ala871= p.A871= ENST00000285199 NM_001267576.1 871 gcC/gcT 0 +USP44 UCSF GRCh37 12 95926690 95926690 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 68 182 0 ENST00000258499.3:c.1343C>T p.Ala448Val p.A448V ENST00000258499 NM_032147.3 448 gCt/gTt 0 +USP48 UCSF GRCh37 1 22083161 22083161 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 102 244 0 ENST00000308271.9:c.290C>T p.Thr97Ile p.T97I ENST00000308271 NM_032236.5 97 aCt/aTt 0 +USP51 UCSF GRCh37 X 55513774 55513774 + synonymous_variant Silent SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 8 51 69 0 ENST00000500968.3:c.1599T>G p.Ala533= p.A533= ENST00000500968 NM_201286.3 533 gcT/gcG 0 +USP7 UCSF GRCh37 16 8997143 8997143 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 120 49 139 0 ENST00000344836.4:c.1821G>A p.Gln607= p.Q607= ENST00000344836 NM_003470.2 607 caG/caA 0 +USP7 UCSF GRCh37 16 9009190 9009190 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 227 92 203 0 ENST00000344836.4:c.999G>A p.Gln333= p.Q333= ENST00000344836 NM_003470.2 333 caG/caA 0 +USPL1 UCSF GRCh37 13 31232629 31232629 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 103 55 189 0 ENST00000255304.4:c.2415C>T p.Asn805= p.N805= ENST00000255304 NM_005800.4 805 aaC/aaT 0 +VAMP1 UCSF GRCh37 12 6575007 6575007 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 54 69 124 0 ENST00000396308.3:c.288+1G>A p.X96_splice ENST00000396308 NM_199245.1 0 +VAMP4 UCSF GRCh37 1 171697711 171697711 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 27 21 49 0 ENST00000236192.7:c.67-1G>A p.X23_splice ENST00000236192 NM_003762.4 0 +VANGL1 UCSF GRCh37 1 116206884 116206884 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 27 19 52 0 ENST00000355485.2:c.807C>T p.His269= p.H269= ENST00000355485 NM_001172411.1 269 caC/caT 0 +VARS UCSF GRCh37 6 31760855 31760855 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 46 34 60 0 ENST00000375663.3:c.430G>A p.Glu144Lys p.E144K ENST00000375663 NM_006295.2 144 Gag/Aag 0 +VARS2 UCSF GRCh37 6 30882677 30882677 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 58 64 134 0 ENST00000541562.1:c.154C>T p.Leu52Phe p.L52F ENST00000541562 NM_001167734.1 52 Ctc/Ttc 0 +VARS2 UCSF GRCh37 6 30892185 30892185 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 19 25 62 0 ENST00000541562.1:c.2611G>A p.Val871Ile p.V871I ENST00000541562 NM_001167734.1 871 Gtc/Atc 0 +VAT1 UCSF GRCh37 17 41168536 41168536 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 29 70 0 ENST00000355653.3:c.886C>T p.Arg296Trp p.R296W ENST00000355653 NM_006373.3 296 Cgg/Tgg 0 +VAV2 UCSF GRCh37 9 136857324 136857324 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 9 15 0 ENST00000371850.3:c.77C>T p.Pro26Leu p.P26L ENST00000371850 NM_001134398.1 26 cCc/cTc 0 +VAX2 UCSF GRCh37 2 71160000 71160000 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 31 22 67 0 ENST00000234392.2:c.539C>T p.Ser180Phe p.S180F ENST00000234392 NM_012476.2 180 tCc/tTc 0 +VEGFC UCSF GRCh37 4 177649081 177649081 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 96 69 150 0 ENST00000280193.2:c.403G>A p.Glu135Lys p.E135K ENST00000280193 NM_005429.3 135 Gag/Aag 0 +VGLL3 UCSF GRCh37 3 87039824 87039824 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 29 10 44 0 ENST00000398399.2:c.70G>A p.Ala24Thr p.A24T ENST00000398399 NM_016206.2 24 Gca/Aca 0 +VIL1 UCSF GRCh37 2 219295554 219295554 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 56 34 103 0 ENST00000248444.5:c.1055C>T p.Ser352Phe p.S352F ENST00000248444 NM_007127.2 352 tCc/tTc 0 +VIL1 UCSF GRCh37 2 219301967 219301967 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 73 145 0 ENST00000248444.5:c.2092G>A p.Val698Met p.V698M ENST00000248444 NM_007127.2 698 Gtg/Atg 0 +VIPR2 UCSF GRCh37 7 158824555 158824555 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 43 113 0 ENST00000262178.2:c.1107G>A p.Leu369= p.L369= ENST00000262178 NM_003382.4 369 ctG/ctA 0 +VIT UCSF GRCh37 2 37041492 37041492 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 20 64 147 0 ENST00000379242.3:c.2070G>A p.Gln690= p.Q690= ENST00000379242 NM_053276.3 690 caG/caA 0 +VOPP1 UCSF GRCh37 7 55560094 55560094 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 23 13 41 0 ENST00000285279.5:c.209G>A p.Gly70Asp p.G70D ENST00000285279 NM_030796.3 70 gGc/gAc 0 +VPRBP UCSF GRCh37 3 51475733 51475733 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 211 150 346 0 ENST00000504652.1:c.694G>A p.Glu232Lys p.E232K ENST00000504652 232 Gaa/Aaa 0 +VPS13D UCSF GRCh37 1 12429692 12429692 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 139 99 228 0 ENST00000358136.3:c.10743C>T p.Phe3581= p.F3581= ENST00000358136 NM_015378.2 3581 ttC/ttT 0 +VPS13D UCSF GRCh37 1 12557575 12557575 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 66 110 0 ENST00000358136.3:c.12684G>A p.Arg4228= p.R4228= ENST00000358136 NM_015378.2 4228 cgG/cgA 0 +VPS33A UCSF GRCh37 12 122726966 122726966 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 94 209 0 ENST00000267199.4:c.1059C>T p.Asn353= p.N353= ENST00000267199 NM_022916.4 353 aaC/aaT 0 +VPS33B UCSF GRCh37 15 91543182 91543182 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 126 102 205 0 ENST00000333371.3:c.1605G>A p.Gln535= p.Q535= ENST00000333371 NM_018668.3 535 caG/caA 0 +VPS39 UCSF GRCh37 15 42454583 42454583 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 74 51 116 0 ENST00000318006.5:c.2272C>T p.Gln758Ter p.Q758* ENST00000318006 NM_015289.2 758 Cag/Tag 0 +VPS39 UCSF GRCh37 15 42453939 42453939 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 175 109 221 0 ENST00000318006.5:c.2493G>A p.Val831= p.V831= ENST00000318006 NM_015289.2 831 gtG/gtA 0 +VPS53 UCSF GRCh37 17 465893 465893 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 70 65 118 0 ENST00000437048.2:c.1406C>T p.Pro469Leu p.P469L ENST00000437048 NM_001128159.2 469 cCc/cTc 0 +VPS54 UCSF GRCh37 2 64161058 64161058 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 19 56 117 0 ENST00000272322.4:c.1488G>A p.Lys496= p.K496= ENST00000272322 496 aaG/aaA 0 +VSIG10L UCSF GRCh37 19 51840535 51840535 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 28 19 51 0 ENST00000335624.4:c.2262G>A p.Gly754= p.G754= ENST00000335624 NM_001163922.1 754 ggG/ggA 0 +VSTM4 UCSF GRCh37 10 50315883 50315883 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 64 46 142 0 ENST00000332853.4:c.213G>A p.Gln71= p.Q71= ENST00000332853 NM_001031746.3 71 caG/caA 0 +VTN UCSF GRCh37 17 26694933 26694933 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 32 25 62 0 ENST00000226218.4:c.1127G>A p.Arg376His p.R376H ENST00000226218 NM_000638.3 376 cGc/cAc 0 +VWA3B UCSF GRCh37 2 98846658 98846658 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 79 61 118 0 ENST00000477737.1:c.2296G>A p.Val766Ile p.V766I ENST00000477737 NM_144992.4 766 Gtc/Atc 0 +VWA5B2 UCSF GRCh37 3 183958847 183958847 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 16 35 0 ENST00000426955.2:c.2914C>T p.His972Tyr p.H972Y ENST00000426955 NM_138345.1 972 Cac/Tac 0 +VWDE UCSF GRCh37 7 12376886 12376886 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 77 45 122 0 ENST00000275358.3:c.4379C>T p.Pro1460Leu p.P1460L ENST00000275358 NM_001135924.1 1460 cCt/cTt 0 +WAPAL UCSF GRCh37 10 88211755 88211755 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 97 79 165 0 ENST00000298767.5:c.3083G>A p.Gly1028Glu p.G1028E ENST00000298767 NM_015045.2 1028 gGa/gAa 0 +WAPAL UCSF GRCh37 10 88233649 88233649 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 142 90 212 0 ENST00000298767.5:c.1726C>T p.Pro576Ser p.P576S ENST00000298767 NM_015045.2 576 Cct/Tct 0 +WBP4 UCSF GRCh37 13 41639178 41639178 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 49 134 0 ENST00000379487.3:c.102G>A p.Lys34= p.K34= ENST00000379487 NM_007187.3 34 aaG/aaA 0 +WDFY3 UCSF GRCh37 4 85771060 85771060 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 154 100 247 0 ENST00000295888.4:c.299C>T p.Ser100Phe p.S100F ENST00000295888 NM_014991.4 100 tCc/tTc 0 +WDFY3 UCSF GRCh37 4 85599335 85599335 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 91 72 177 0 ENST00000295888.4:c.10245C>T p.Ala3415= p.A3415= ENST00000295888 NM_014991.4 3415 gcC/gcT 0 +WDFY3 UCSF GRCh37 4 85605246 85605246 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 93 50 143 0 ENST00000295888.4:c.9576C>T p.Ile3192= p.I3192= ENST00000295888 NM_014991.4 3192 atC/atT 0 +WDFY4 UCSF GRCh37 10 50040716 50040716 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 112 108 168 0 ENST00000325239.5:c.6625C>T p.Pro2209Ser p.P2209S ENST00000325239 NM_020945.1 2209 Ccc/Tcc 0 +WDFY4 UCSF GRCh37 10 49951044 49951044 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 29 21 51 0 ENST00000325239.5:c.1910G>A p.Gly637Asp p.G637D ENST00000325239 NM_020945.1 637 gGt/gAt 0 +WDR11 UCSF GRCh37 10 122645451 122645451 + splice_donor_variant Splice_Site SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 68 144 0 ENST00000263461.6:c.1973+1G>A p.X658_splice ENST00000263461 NM_018117.11 0 +WDR36 UCSF GRCh37 5 110441832 110441832 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 80 162 0 ENST00000506538.2:c.1338G>A p.Lys446= p.K446= ENST00000506538 NM_139281.2 446 aaG/aaA 0 +WDR47 UCSF GRCh37 1 109533922 109533922 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 88 193 1 ENST00000400794.3:c.1745C>T p.Pro582Leu p.P582L ENST00000400794 582 cCt/cTt 0 +WDR48 UCSF GRCh37 3 39116230 39116230 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 80 52 111 0 ENST00000302313.5:c.686G>A p.Ser229Asn p.S229N ENST00000302313 NM_020839.2 229 aGt/aAt 0 +WDR54 UCSF GRCh37 2 74650480 74650480 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 127 111 187 0 ENST00000348227.4:c.320G>A p.Trp107Ter p.W107* ENST00000348227 NM_032118.2 107 tGg/tAg 0 +WDR60 UCSF GRCh37 7 158662547 158662547 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 100 68 186 0 ENST00000407559.3:c.17G>A p.Arg6Lys p.R6K ENST00000407559 NM_018051.4 6 aGa/aAa 0 +WDR61 UCSF GRCh37 15 78585531 78585531 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 80 184 0 ENST00000267973.2:c.124G>A p.Asp42Asn p.D42N ENST00000267973 42 Gac/Aac 0 +WDR63 UCSF GRCh37 1 85592310 85592310 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 82 75 139 0 ENST00000294664.6:c.2229G>A p.Trp743Ter p.W743* ENST00000294664 NM_145172.3 743 tgG/tgA 0 +WDR69 UCSF GRCh37 2 228786134 228786134 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 109 96 182 0 ENST00000309931.2:c.1070G>A p.Gly357Glu p.G357E ENST00000309931 NM_178821.1 357 gGg/gAg 0 +WDR76 UCSF GRCh37 15 44158475 44158475 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 106 122 212 0 ENST00000263795.6:c.1766G>A p.Gly589Glu p.G589E ENST00000263795 NM_001167941.1 589 gGa/gAa 0 +WDR82 UCSF GRCh37 3 52293841 52293841 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 201 139 258 0 ENST00000296490.3:c.591G>A p.Trp197Ter p.W197* ENST00000296490 NM_025222.3 197 tgG/tgA 0 +WDR87 UCSF GRCh37 19 38377607 38377607 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 104 241 0 ENST00000303868.5:c.6587G>A p.Arg2196Lys p.R2196K ENST00000303868 NM_031951.3 2196 aGg/aAg 0 +WDR87 UCSF GRCh37 19 38385526 38385526 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 25 17 33 0 ENST00000303868.5:c.700G>A p.Gly234Ser p.G234S ENST00000303868 NM_031951.3 234 Ggc/Agc 0 +WDR90 UCSF GRCh37 16 706475 706475 + stop_gained Nonsense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 3 16 0 ENST00000293879.4:c.2140C>T p.Gln714Ter p.Q714* ENST00000293879 714 Cag/Tag 0 +WDR91 UCSF GRCh37 7 134873185 134873185 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 74 142 0 ENST00000354475.4:c.1881G>A p.Lys627= p.K627= ENST00000354475 NM_014149.3 627 aaG/aaA 0 +WFDC12 UCSF GRCh37 20 43752816 43752816 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 34 123 0 ENST00000372785.3:c.170G>A p.Gly57Glu p.G57E ENST00000372785 NM_080869.1 57 gGg/gAg 0 +WFDC12 UCSF GRCh37 20 43752779 43752779 + missense_variant Missense_Mutation SNP C C G NOVEL P18_Rec Untested WXS Illumina HiSeq 65 34 114 0 ENST00000372785.3:c.207G>C p.Lys69Asn p.K69N ENST00000372785 NM_080869.1 69 aaG/aaC 0 +WHSC1 UCSF GRCh37 4 1902712 1902712 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 72 65 140 0 ENST00000382891.5:c.331C>T p.Pro111Ser p.P111S ENST00000382891 NM_133335.3 111 Ccc/Tcc 0 +WHSC1 UCSF GRCh37 4 1936936 1936936 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 111 213 0 ENST00000382891.5:c.1621G>A p.Ala541Thr p.A541T ENST00000382891 NM_133335.3 541 Gct/Act 0 +WHSC1 UCSF GRCh37 4 1962801 1962801 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 101 208 0 ENST00000382891.5:c.3295G>A p.Glu1099Lys p.E1099K ENST00000382891 NM_133335.3 1099 Gag/Aag 0 +WIPI2 UCSF GRCh37 7 5254295 5254295 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 133 109 226 0 ENST00000288828.4:c.341G>A p.Ser114Asn p.S114N ENST00000288828 NM_001278299.1 114 aGc/aAc 0 +WIZ UCSF GRCh37 19 15537936 15537936 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 43 91 0 ENST00000263381.7:c.938C>T p.Pro313Leu p.P313L ENST00000263381 NM_021241.2 313 cCc/cTc 0 +WNK3 UCSF GRCh37 X 54259424 54259424 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 16 89 106 0 ENST00000354646.2:c.4658C>T p.Thr1553Ile p.T1553I ENST00000354646 NM_020922.4 1553 aCc/aTc 0 +WNT1 UCSF GRCh37 12 49373497 49373497 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 8 24 48 0 ENST00000293549.3:c.351C>T p.Val117= p.V117= ENST00000293549 NM_005430.3 117 gtC/gtT 0 +WNT2B UCSF GRCh37 1 113057690 113057690 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 51 38 93 0 ENST00000369684.4:c.377C>T p.Thr126Ile p.T126I ENST00000369684 NM_024494.2 126 aCc/aTc 0 +WNT7B UCSF GRCh37 22 46327072 46327072 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 59 34 103 0 ENST00000339464.4:c.476G>A p.Gly159Asp p.G159D ENST00000339464 NM_058238.2 159 gGc/gAc 0 +WNT9A UCSF GRCh37 1 228109320 228109320 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 40 26 68 0 ENST00000272164.5:c.997C>T p.Arg333Trp p.R333W ENST00000272164 NM_003395.2 333 Cgg/Tgg 0 +WSB2 UCSF GRCh37 12 118476159 118476159 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 36 77 0 ENST00000315436.3:c.594G>A p.Gln198= p.Q198= ENST00000315436 NM_018639.4 198 caG/caA 0 +WWP2 UCSF GRCh37 16 69964091 69964091 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 46 61 86 0 ENST00000359154.2:c.1375G>A p.Val459Met p.V459M ENST00000359154 NM_001270454.1 459 Gtg/Atg 0 +WWTR1 UCSF GRCh37 3 149260308 149260308 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 42 108 0 ENST00000360632.3:c.585C>T p.His195= p.H195= ENST00000360632 NM_015472.4 195 caC/caT 0 +XCL2 UCSF GRCh37 1 168510233 168510233 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 71 67 145 0 ENST00000367819.2:c.302G>A p.Gly101Glu p.G101E ENST00000367819 NM_003175.3 101 gGa/gAa 0 +XCR1 UCSF GRCh37 3 46063248 46063248 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 47 50 98 0 ENST00000309285.3:c.192C>T p.Ser64= p.S64= ENST00000309285 NM_001024644.1 64 tcC/tcT 0 +XIRP1 UCSF GRCh37 3 39228860 39228860 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 55 103 0 ENST00000340369.3:c.2077G>A p.Val693Met p.V693M ENST00000340369 NM_194293.2 693 Gtg/Atg 0 +XIRP1 UCSF GRCh37 3 39229708 39229708 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 178 133 249 0 ENST00000340369.3:c.1229G>A p.Gly410Asp p.G410D ENST00000340369 NM_194293.2 410 gGt/gAt 0 +XIRP1 UCSF GRCh37 3 39228192 39228192 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 60 29 83 0 ENST00000340369.3:c.2745G>A p.Arg915= p.R915= ENST00000340369 NM_194293.2 915 cgG/cgA 0 +XIRP2 UCSF GRCh37 2 168103905 168103905 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 86 77 142 0 ENST00000409195.1:c.6003G>A p.Met2001Ile p.M2001I ENST00000409195 NM_152381.5 2001 atG/atA 0 +XIRP2 UCSF GRCh37 2 168107768 168107768 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 150 101 244 0 ENST00000409195.1:c.9866G>C p.Ser3289Thr p.S3289T ENST00000409195 NM_152381.5 3289 aGt/aCt 0 +XIRP2 UCSF GRCh37 2 168115309 168115309 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 72 198 0 ENST00000409195.1:c.*982G>A *328* ENST00000409195 NM_152381.5 0 +XKR7 UCSF GRCh37 20 30584735 30584735 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 59 136 0 ENST00000562532.2:c.1215C>T p.Ser405= p.S405= ENST00000562532 NM_001011718.1 405 agC/agT 0 +XKRX UCSF GRCh37 X 100169423 100169423 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 26 147 144 0 ENST00000372956.2:c.1254C>T p.Asp418= p.D418= ENST00000372956 418 gaC/gaT 0 +XPR1 UCSF GRCh37 1 180772570 180772570 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 90 161 0 ENST00000367590.4:c.270G>A p.Glu90= p.E90= ENST00000367590 NM_004736.3 90 gaG/gaA 0 +YSK4 UCSF GRCh37 2 135744645 135744645 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 160 96 248 0 ENST00000375845.3:c.1797G>A p.Lys599= p.K599= ENST00000375845 NM_025052.3 599 aaG/aaA 0 +YTHDC1 UCSF GRCh37 4 69196001 69196001 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 33 100 0 ENST00000344157.4:c.1150G>A p.Glu384Lys p.E384K ENST00000344157 NM_001031732.2 384 Gag/Aag 0 +YTHDC1 UCSF GRCh37 4 69184300 69184300 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 46 83 0 ENST00000344157.4:c.1762-1G>A p.X588_splice ENST00000344157 NM_001031732.2 0 +YTHDC2 UCSF GRCh37 5 112851004 112851004 + missense_variant Missense_Mutation SNP A A G NOVEL P18_Rec Untested WXS Illumina HiSeq 142 92 169 0 ENST00000161863.4:c.223A>G p.Arg75Gly p.R75G ENST00000161863 NM_022828.3 75 Aga/Gga 0 +YTHDF2 UCSF GRCh37 1 29069051 29069051 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 156 109 261 0 ENST00000373812.3:c.269G>A p.Gly90Glu p.G90E ENST00000373812 NM_016258.2 90 gGa/gAa 0 +YY1 UCSF GRCh37 14 100742893 100742893 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 121 80 190 0 ENST00000262238.4:c.970G>A p.Val324Ile p.V324I ENST00000262238 NM_003403.4 324 Gtc/Atc 0 +YY1 UCSF GRCh37 14 100743830 100743830 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 118 86 187 0 ENST00000262238.4:c.1138G>A p.Asp380Asn p.D380N ENST00000262238 NM_003403.4 380 Gac/Aac 0 +ZAN UCSF GRCh37 7 100350307 100350307 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 10 16 15 0 ENST00000546292.1:c.2579C>T p.Pro860Leu p.P860L ENST00000546292 NM_173059.1 860 cCc/cTc 0 +ZAN UCSF GRCh37 7 100383720 100383720 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 128 78 177 0 ENST00000546292.1:c.6933C>T p.Cys2311= p.C2311= ENST00000546292 NM_173059.1 2311 tgC/tgT 0 +ZAN UCSF GRCh37 7 100365518 100365518 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 90 69 123 0 ENST00000546292.1:c.4925G>A p.Ser1642Asn p.S1642N ENST00000546292 NM_173059.1 1642 aGc/aAc 0 +ZBED4 UCSF GRCh37 22 50278716 50278716 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 108 91 205 0 ENST00000216268.5:c.1406C>T p.Pro469Leu p.P469L ENST00000216268 NM_014838.2 469 cCc/cTc 0 +ZBTB11 UCSF GRCh37 3 101371436 101371436 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 132 91 248 0 ENST00000312938.4:c.2548G>A p.Gly850Arg p.G850R ENST00000312938 NM_014415.3 850 Gga/Aga 0 +ZBTB38 UCSF GRCh37 3 141164212 141164212 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 50 42 84 0 ENST00000514251.1:c.2982G>A p.Gly994= p.G994= ENST00000514251 994 ggG/ggA 0 +ZBTB45 UCSF GRCh37 19 59028884 59028884 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 66 51 121 0 ENST00000594051.1:c.157G>A p.Ala53Thr p.A53T ENST00000594051 53 Gcc/Acc 0 +ZBTB45 UCSF GRCh37 19 59028490 59028490 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 59 126 0 ENST00000594051.1:c.551C>T p.Pro184Leu p.P184L ENST00000594051 184 cCc/cTc 0 +ZBTB7C UCSF GRCh37 18 45566509 45566509 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 46 123 0 ENST00000588982.1:c.970C>T p.Pro324Ser p.P324S ENST00000588982 324 Ccc/Tcc 0 +ZC3H12A UCSF GRCh37 1 37948447 37948447 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 88 51 116 0 ENST00000373087.6:c.1035C>T p.Pro345= p.P345= ENST00000373087 NM_025079.2 345 ccC/ccT 0 +ZC3H12C UCSF GRCh37 11 110035699 110035699 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 177 143 297 0 ENST00000278590.3:c.1889G>A p.Gly630Glu p.G630E ENST00000278590 NM_033390.1 630 gGg/gAg 0 +ZC3H6 UCSF GRCh37 2 113069414 113069414 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 98 240 0 ENST00000409871.1:c.647G>A p.Gly216Asp p.G216D ENST00000409871 NM_198581.2 216 gGt/gAt 0 +ZC3H6 UCSF GRCh37 2 113088668 113088668 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 90 195 0 ENST00000409871.1:c.2173G>A p.Glu725Lys p.E725K ENST00000409871 NM_198581.2 725 Gaa/Aaa 0 +ZC3H6 UCSF GRCh37 2 113089968 113089968 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 153 105 234 0 ENST00000409871.1:c.3473G>A p.Ser1158Asn p.S1158N ENST00000409871 NM_198581.2 1158 aGc/aAc 0 +ZCCHC14 UCSF GRCh37 16 87445700 87445700 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 25 67 0 ENST00000268616.4:c.2216C>T p.Pro739Leu p.P739L ENST00000268616 NM_015144.2 739 cCt/cTt 0 +ZCWPW2 UCSF GRCh37 3 28476702 28476702 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 124 94 181 0 ENST00000383768.2:c.434C>T p.Pro145Leu p.P145L ENST00000383768 145 cCc/cTc 0 +ZDHHC17 UCSF GRCh37 12 77244705 77244705 + stop_gained Nonsense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 176 123 306 0 ENST00000426126.2:c.1839G>A p.Trp613Ter p.W613* ENST00000426126 NM_015336.2 613 tgG/tgA 0 +ZDHHC23 UCSF GRCh37 3 113673143 113673143 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 50 37 105 0 ENST00000330212.3:c.758C>T p.Pro253Leu p.P253L ENST00000330212 NM_173570.3 253 cCc/cTc 0 +ZEB1 UCSF GRCh37 10 31812964 31812964 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 357 129 302 0 ENST00000361642.5:c.2708G>A p.Gly903Glu p.G903E ENST00000361642 NM_001174093.1 903 gGa/gAa 0 +ZFC3H1 UCSF GRCh37 12 72020039 72020039 + splice_donor_variant Splice_Site SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 17 70 168 0 ENST00000378743.3:c.4317+1G>A p.X1439_splice ENST00000378743 NM_144982.4 0 +ZFHX2 UCSF GRCh37 14 24002695 24002695 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 44 29 58 0 ENST00000419474.3:c.1840G>A p.Gly614Arg p.G614R ENST00000419474 NM_033400.2 614 Ggg/Agg 0 +ZFHX2 UCSF GRCh37 14 24004210 24004210 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 52 44 118 0 ENST00000419474.3:c.325G>A p.Asp109Asn p.D109N ENST00000419474 NM_033400.2 109 Gac/Aac 0 +ZFHX3 UCSF GRCh37 16 72829959 72829959 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 144 103 218 0 ENST00000268489.5:c.6622C>T p.Pro2208Ser p.P2208S ENST00000268489 NM_006885.3 2208 Cct/Tct 0 +ZFP30 UCSF GRCh37 19 38126599 38126599 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 117 93 207 0 ENST00000351218.2:c.843G>A p.Gln281= p.Q281= ENST00000351218 NM_014898.2 281 caG/caA 0 +ZFP92 UCSF GRCh37 X 152686803 152686803 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 1 24 28 0 ENST00000338647.5:c.968G>A p.Arg323His p.R323H ENST00000338647 NM_001136273.1 323 cGc/cAc 0 +ZFPM2 UCSF GRCh37 8 106573677 106573677 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 171 110 254 0 ENST00000407775.2:c.388C>T p.Pro130Ser p.P130S ENST00000407775 NM_012082.3 130 Cct/Tct 0 +ZFY UCSF GRCh37 Y 2829565 2829565 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 24 131 159 0 ENST00000155093.3:c.512T>C p.Ile171Thr p.I171T ENST00000155093 NM_003411.3 171 aTa/aCa 0 +ZFYVE16 UCSF GRCh37 5 79733758 79733758 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 67 154 0 ENST00000338008.5:c.1254G>A p.Gln418= p.Q418= ENST00000338008 NM_014733.3 418 caG/caA 0 +ZFYVE20 UCSF GRCh37 3 15115414 15115414 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 68 163 0 ENST00000253699.3:c.2230G>A p.Asp744Asn p.D744N ENST00000253699 NM_022340.2 744 Gat/Aat 0 +ZFYVE26 UCSF GRCh37 14 68234548 68234548 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 90 82 155 0 ENST00000347230.4:c.5663G>A p.Ser1888Asn p.S1888N ENST00000347230 NM_015346.3 1888 aGc/aAc 0 +ZFYVE26 UCSF GRCh37 14 68264935 68264935 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 83 49 130 0 ENST00000347230.4:c.2044G>A p.Glu682Lys p.E682K ENST00000347230 NM_015346.3 682 Gaa/Aaa 0 +ZFYVE28 UCSF GRCh37 4 2306047 2306047 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 69 48 84 0 ENST00000290974.2:c.2020C>T p.His674Tyr p.H674Y ENST00000290974 NM_020972.2 674 Cac/Tac 0 +ZFYVE9 UCSF GRCh37 1 52803605 52803605 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 38 33 70 0 ENST00000287727.3:c.3832G>A p.Gly1278Ser p.G1278S ENST00000287727 NM_004799.3 1278 Ggt/Agt 0 +ZKSCAN5 UCSF GRCh37 7 99123443 99123443 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 103 99 197 0 ENST00000394170.2:c.780G>A p.Glu260= p.E260= ENST00000394170 NM_014569.3 260 gaG/gaA 0 +ZMYM2 UCSF GRCh37 13 20632781 20632781 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 210 111 313 0 ENST00000382869.3:c.2560C>T p.Pro854Ser p.P854S ENST00000382869 NM_001190965.1 854 Cct/Tct 0 +ZNF12 UCSF GRCh37 7 6730763 6730763 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 167 142 250 0 ENST00000405858.1:c.1810G>A p.Ala604Thr p.A604T ENST00000405858 NM_016265.3 604 Gcc/Acc 0 +ZNF133 UCSF GRCh37 20 18296873 18296873 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 94 71 158 0 ENST00000377671.3:c.1375C>T p.His459Tyr p.H459Y ENST00000377671 NM_003434.4 459 Cac/Tac 0 +ZNF133 UCSF GRCh37 20 18286988 18286988 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 53 33 84 0 ENST00000377671.3:c.168G>A p.Gly56= p.G56= ENST00000377671 NM_003434.4 56 ggG/ggA 0 +ZNF141 UCSF GRCh37 4 367239 367239 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 212 105 306 0 ENST00000240499.7:c.1013C>T p.Pro338Leu p.P338L ENST00000240499 NM_003441.2 338 cCc/cTc 0 +ZNF148 UCSF GRCh37 3 125007042 125007042 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 91 68 125 0 ENST00000360647.4:c.364G>A p.Asp122Asn p.D122N ENST00000360647 NM_021964.2 122 Gat/Aat 0 +ZNF167 UCSF GRCh37 3 44612845 44612845 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 89 216 0 ENST00000273320.3:c.2243G>A p.Gly748Asp p.G748D ENST00000273320 NM_018651.2 748 gGt/gAt 0 +ZNF189 UCSF GRCh37 9 104171069 104171069 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 167 113 197 0 ENST00000339664.2:c.1019G>A p.Gly340Asp p.G340D ENST00000339664 NM_001278240.1 340 gGc/gAc 0 +ZNF207 UCSF GRCh37 17 30688510 30688510 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 73 25 82 0 ENST00000394670.4:c.575C>T p.Thr192Ile p.T192I ENST00000394670 NM_001098507.1 192 aCc/aTc 0 +ZNF208 UCSF GRCh37 19 22156272 22156272 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 147 104 314 0 ENST00000397126.4:c.1564G>A p.Glu522Lys p.E522K ENST00000397126 NM_007153.3 522 Gag/Aag 0 +ZNF232 UCSF GRCh37 17 5009700 5009700 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 116 77 198 0 ENST00000250076.3:c.754G>A p.Asp252Asn p.D252N ENST00000250076 NM_014519.2 252 Gac/Aac 0 +ZNF259 UCSF GRCh37 11 116655613 116655613 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 54 42 96 0 ENST00000227322.3:c.778C>T p.Pro260Ser p.P260S ENST00000227322 NM_003904.3 260 Cca/Tca 0 +ZNF273 UCSF GRCh37 7 64388509 64388509 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 48 167 0 ENST00000476120.1:c.803G>A p.Gly268Asp p.G268D ENST00000476120 NM_021148.2 268 gGc/gAc 0 +ZNF273 UCSF GRCh37 7 64378666 64378666 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 189 89 244 0 ENST00000476120.1:c.321C>T p.Pro107= p.P107= ENST00000476120 NM_021148.2 107 ccC/ccT 0 +ZNF274 UCSF GRCh37 19 58718448 58718448 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 43 19 53 0 ENST00000326804.4:c.616G>A p.Glu206Lys p.E206K ENST00000326804 NM_133502.2 206 Gag/Aag 0 +ZNF276 UCSF GRCh37 16 89804646 89804646 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 16 17 28 0 ENST00000443381.2:c.1837C>T p.Pro613Ser p.P613S ENST00000443381 NM_001113525.1 613 Ccc/Tcc 0 +ZNF280D UCSF GRCh37 15 56968955 56968955 + missense_variant Missense_Mutation SNP A A C NOVEL P18_Rec Untested WXS Illumina HiSeq 158 97 209 0 ENST00000267807.7:c.1323T>G p.His441Gln p.H441Q ENST00000267807 NM_017661.2 441 caT/caG 0 +ZNF280D UCSF GRCh37 15 56969839 56969839 + missense_variant Missense_Mutation SNP G G C NOVEL P18_Rec Untested WXS Illumina HiSeq 75 46 114 0 ENST00000267807.7:c.1196C>G p.Thr399Arg p.T399R ENST00000267807 NM_017661.2 399 aCa/aGa 0 +ZNF281 UCSF GRCh37 1 200376691 200376691 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 98 219 0 ENST00000294740.3:c.2143C>T p.Pro715Ser p.P715S ENST00000294740 NM_001281293.1 715 Cct/Tct 0 +ZNF282 UCSF GRCh37 7 148895529 148895529 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 97 72 141 0 ENST00000262085.3:c.270G>A p.Gln90= p.Q90= ENST00000262085 NM_003575.2 90 caG/caA 0 +ZNF317 UCSF GRCh37 19 9271310 9271310 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 72 45 119 0 ENST00000247956.6:c.989G>A p.Gly330Glu p.G330E ENST00000247956 NM_020933.4 330 gGa/gAa 0 +ZNF335 UCSF GRCh37 20 44596467 44596467 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 48 30 104 0 ENST00000322927.2:c.720G>A p.Val240= p.V240= ENST00000322927 NM_022095.3 240 gtG/gtA 0 +ZNF343 UCSF GRCh37 20 2464326 2464326 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 138 93 210 0 ENST00000278772.4:c.1281C>T p.His427= p.H427= ENST00000278772 NM_024325.4 427 caC/caT 0 +ZNF418 UCSF GRCh37 19 58437817 58437817 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 137 93 225 0 ENST00000396147.1:c.1732C>T p.Leu578Phe p.L578F ENST00000396147 NM_133460.1 578 Ctc/Ttc 0 +ZNF432 UCSF GRCh37 19 52537770 52537770 + missense_variant Missense_Mutation SNP T T C NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 166 133 272 0 ENST00000594154.1:c.1162A>G p.Met388Val p.M388V ENST00000594154 388 Atg/Gtg 0 +ZNF434 UCSF GRCh37 16 3433147 3433147 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 157 85 134 0 ENST00000304926.3:c.1163C>T p.Thr388Ile p.T388I ENST00000304926 NM_017810.2 388 aCc/aTc 0 +ZNF440 UCSF GRCh37 19 11943637 11943637 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 136 99 216 0 ENST00000304060.5:c.1646G>A p.Gly549Glu p.G549E ENST00000304060 NM_152357.2 549 gGa/gAa 0 +ZNF445 UCSF GRCh37 3 44488170 44488170 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 150 129 275 0 ENST00000425708.2:c.2993G>A p.Arg998Lys p.R998K ENST00000425708 998 aGa/aAa 0 +ZNF451 UCSF GRCh37 6 57017077 57017077 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 68 66 154 0 ENST00000370706.4:c.2811G>A p.Arg937= p.R937= ENST00000370706 NM_001031623.2 937 agG/agA 0 +ZNF462 UCSF GRCh37 9 109688504 109688504 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 102 76 164 0 ENST00000277225.5:c.2311G>A p.Glu771Lys p.E771K ENST00000277225 771 Gag/Aag 0 +ZNF462 UCSF GRCh37 9 109691673 109691673 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 112 78 150 0 ENST00000277225.5:c.5480G>A p.Gly1827Asp p.G1827D ENST00000277225 1827 gGc/gAc 0 +ZNF473 UCSF GRCh37 19 50542435 50542435 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 96 65 162 0 ENST00000595661.1:c.27G>A p.Lys9= p.K9= ENST00000595661 9 aaG/aaA 0 +ZNF496 UCSF GRCh37 1 247473629 247473629 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 56 50 106 0 ENST00000294753.4:c.781C>T p.Pro261Ser p.P261S ENST00000294753 NM_032752.1 261 Cca/Tca 0 +ZNF497 UCSF GRCh37 19 58867996 58867996 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 9 10 18 0 ENST00000311044.3:c.1006G>A p.Gly336Ser p.G336S ENST00000311044 NM_198458.2 336 Ggc/Agc 0 +ZNF500 UCSF GRCh37 16 4815955 4815955 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 120 42 118 0 ENST00000219478.6:c.25C>T p.Pro9Ser p.P9S ENST00000219478 9 Ccc/Tcc 0 +ZNF500 UCSF GRCh37 16 4815944 4815944 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 119 58 112 0 ENST00000219478.6:c.36C>T p.Thr12= p.T12= ENST00000219478 12 acC/acT 0 +ZNF513 UCSF GRCh37 2 27600534 27600534 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0011 P18_Rec Untested WXS Illumina HiSeq 25 65 162 0 ENST00000323703.6:c.1504C>T p.Pro502Ser p.P502S ENST00000323703 NM_144631.5 502 Cct/Tct 0 +ZNF516 UCSF GRCh37 18 74091160 74091160 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 37 27 65 0 ENST00000443185.2:c.2910C>T p.Ala970= p.A970= ENST00000443185 NM_014643.3 970 gcC/gcT 0 +ZNF517 UCSF GRCh37 8 146032905 146032905 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 14 4 26 0 ENST00000359971.3:c.604G>A p.Ala202Thr p.A202T ENST00000359971 NM_213605.2 202 Gcc/Acc 0 +ZNF518B UCSF GRCh37 4 10445190 10445190 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 163 139 254 0 ENST00000326756.3:c.2763G>A p.Arg921= p.R921= ENST00000326756 NM_053042.2 921 agG/agA 0 +ZNF534 UCSF GRCh37 19 52942513 52942513 + synonymous_variant Silent SNP T T C NOVEL P18_Rec Untested WXS Illumina HiSeq 176 132 271 0 ENST00000332323.6:c.1839T>C p.His613= p.H613= ENST00000332323 NM_001143939.1 613 caT/caC 0 +ZNF540 UCSF GRCh37 19 38090612 38090612 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 123 90 182 0 ENST00000592533.1:c.95G>A p.Arg32Lys p.R32K ENST00000592533 NM_152606.4 32 aGa/aAa 0 +ZNF570 UCSF GRCh37 19 37975761 37975761 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec somatic WXS Sanger Illumina HiSeq 156 119 238 0 ENST00000330173.1:c.1237C>T p.Pro413Ser p.P413S ENST00000330173 NM_144694.1 413 Cct/Tct 0 +ZNF570 UCSF GRCh37 19 37975724 37975724 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 149 106 191 0 ENST00000330173.1:c.1200C>T p.His400= p.H400= ENST00000330173 NM_144694.1 400 caC/caT 0 +ZNF586 UCSF GRCh37 19 58290725 58290725 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 80 246 0 ENST00000396154.2:c.770C>T p.Thr257Ile p.T257I ENST00000396154 NM_017652.3 257 aCa/aTa 0 +ZNF592 UCSF GRCh37 15 85326026 85326026 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 129 104 226 0 ENST00000299927.3:c.120C>T p.Pro40= p.P40= ENST00000299927 40 ccC/ccT 0 +ZNF608 UCSF GRCh37 5 124079985 124079985 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 99 62 144 0 ENST00000306315.5:c.698G>A p.Gly233Glu p.G233E ENST00000306315 NM_020747.2 233 gGg/gAg 0 +ZNF621 UCSF GRCh37 3 40571750 40571750 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 75 57 107 0 ENST00000339296.5:c.202G>A p.Glu68Lys p.E68K ENST00000339296 NM_198484.3 68 Gaa/Aaa 0 +ZNF628 UCSF GRCh37 19 55995469 55995469 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 13 15 15 0 ENST00000598519.1:c.2909C>T p.Pro970Leu p.P970L ENST00000598519 NM_033113.2 970 cCc/cTc 0 +ZNF646 UCSF GRCh37 16 31088860 31088860 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 34 15 43 0 ENST00000300850.5:c.1215C>T p.Leu405= p.L405= ENST00000300850 NM_014699.3 405 ctC/ctT 0 +ZNF648 UCSF GRCh37 1 182026975 182026975 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 56 159 0 ENST00000339948.3:c.171C>T p.Gly57= p.G57= ENST00000339948 NM_001009992.1 57 ggC/ggT 0 +ZNF672 UCSF GRCh37 1 249142351 249142351 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 12 24 32 0 ENST00000306562.3:c.878G>A p.Gly293Glu p.G293E ENST00000306562 NM_024836.1 293 gGg/gAg 0 +ZNF691 UCSF GRCh37 1 43315411 43315411 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 135 103 201 0 ENST00000397044.3:c.82G>A p.Glu28Lys p.E28K ENST00000397044 28 Gag/Aag 0 +ZNF77 UCSF GRCh37 19 2936675 2936675 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 78 66 113 0 ENST00000314531.4:c.158G>A p.Gly53Glu p.G53E ENST00000314531 NM_021217.2 53 gGa/gAa 0 +ZNF778 UCSF GRCh37 16 89294114 89294114 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 158 124 264 0 ENST00000433976.2:c.1334G>A p.Gly445Glu p.G445E ENST00000433976 NM_001201407.1 445 gGa/gAa 0 +ZNF800 UCSF GRCh37 7 127014204 127014204 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 172 108 250 0 ENST00000393313.1:c.1186G>A p.Gly396Ser p.G396S ENST00000393313 396 Ggc/Agc 0 +ZNF804B UCSF GRCh37 7 88964016 88964016 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 107 76 190 0 ENST00000333190.4:c.1720G>A p.Glu574Lys p.E574K ENST00000333190 NM_181646.2 574 Gaa/Aaa 0 +ZNF836 UCSF GRCh37 19 52660411 52660411 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 227 163 330 0 ENST00000322146.8:c.525C>T p.Ser175= p.S175= ENST00000322146 NM_001102657.1 175 tcC/tcT 0 +ZNF846 UCSF GRCh37 19 9868417 9868417 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 114 87 167 0 ENST00000397902.2:c.1336G>A p.Gly446Arg p.G446R ENST00000397902 NM_001077624.1 446 Gga/Aga 0 +ZNF846 UCSF GRCh37 19 9868865 9868865 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 117 97 197 0 ENST00000397902.2:c.888C>T p.Tyr296= p.Y296= ENST00000397902 NM_001077624.1 296 taC/taT 0 +ZNF862 UCSF GRCh37 7 149558596 149558596 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 33 24 58 0 ENST00000223210.4:c.2347G>A p.Asp783Asn p.D783N ENST00000223210 NM_001099220.1 783 Gat/Aat 0 +ZNHIT3 UCSF GRCh37 17 34842624 34842624 + synonymous_variant Silent SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 65 83 0 ENST00000225410.4:c.81G>A p.Val27= p.V27= ENST00000225410 NM_004773.3 27 gtG/gtA 0 +ZPBP UCSF GRCh37 7 49977191 49977191 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 125 78 171 0 ENST00000046087.2:c.989C>T p.Pro330Leu p.P330L ENST00000046087 NM_007009.2 330 cCc/cTc 0 +ZSCAN10 UCSF GRCh37 16 3142133 3142133 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 84 28 91 0 ENST00000252463.2:c.416C>T p.Pro139Leu p.P139L ENST00000252463 NM_032805.1 139 cCg/cTg 0 +ZSCAN12 UCSF GRCh37 6 28358508 28358508 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 101 75 184 0 ENST00000361028.1:c.1559C>T p.Thr520Ile p.T520I ENST00000361028 520 aCt/aTt 0 +ZSCAN2 UCSF GRCh37 15 85164774 85164774 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 58 69 135 0 ENST00000448803.2:c.1348G>A p.Val450Met p.V450M ENST00000448803 NM_181877.3 450 Gtg/Atg 0 +ZSWIM1 UCSF GRCh37 20 44512582 44512582 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 60 57 92 0 ENST00000372523.1:c.1351G>A p.Gly451Ser p.G451S ENST00000372523 NM_080603.4 451 Ggt/Agt 0 +ZSWIM2 UCSF GRCh37 2 187702039 187702039 + missense_variant Missense_Mutation SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 145 89 204 0 ENST00000295131.2:c.737G>A p.Cys246Tyr p.C246Y ENST00000295131 NM_182521.2 246 tGt/tAt 0 +ZWILCH UCSF GRCh37 15 66807978 66807978 + missense_variant Missense_Mutation SNP G G A NOVEL P18_Rec Untested WXS Illumina HiSeq 78 57 134 0 ENST00000307897.5:c.316G>A p.Ala106Thr p.A106T ENST00000307897 NM_017975.3 106 Gca/Aca 0 +ZYG11B UCSF GRCh37 1 53250719 53250719 + synonymous_variant Silent SNP C C T NOVEL P18_Rec Untested WXS Illumina HiSeq 80 49 111 0 ENST00000294353.6:c.1263C>T p.His421= p.H421= ENST00000294353 NM_024646.2 421 caC/caT 0 +ATRX UCSF GRCh37 X 76845402 76845403 + frameshift_variant Frame_Shift_Del DEL AA AA - NOVEL P21_Pri Untested WXS Illumina HiSeq 36 0 ENST00000373344.5:c.6118_6119del p.Phe2040GlnfsTer11 p.F2040Qfs*11 ENST00000373344 NM_000489.3 2040 TTc/c 0 +CAPN12 UCSF GRCh37 19 39228950 39228950 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 10 8 53 0 ENST00000328867.4:c.928G>A p.Asp310Asn p.D310N ENST00000328867 NM_144691.3 310 Gat/Aat 0 +CDC16 UCSF GRCh37 13 115002355 115002355 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 74 58 95 0 ENST00000360383.3:c.185C>T p.Ser62Leu p.S62L ENST00000360383 NM_001078645.1 62 tCa/tTa 0 +CDKN1B UCSF GRCh37 12 12870849 12870849 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P21_Pri somatic WXS Sanger Illumina HiSeq 186 0 ENST00000228872.4:c.78del p.Ser27ArgfsTer15 p.S27Rfs*15 ENST00000228872 NM_004064.3 26 Ccc/cc 0 +CENPE UCSF GRCh37 4 104066758 104066758 + synonymous_variant Silent SNP C C G NOVEL P21_Pri Untested WXS Illumina HiSeq 134 17 239 0 ENST00000265148.3:c.4494G>C p.Val1498= p.V1498= ENST00000265148 NM_001813.2 1498 gtG/gtC 0 +COL6A3 UCSF GRCh37 2 238289888 238289888 + synonymous_variant Silent SNP G G A NOVEL P21_Pri Untested WXS Illumina HiSeq 130 32 303 0 ENST00000295550.4:c.1567C>T p.Leu523= p.L523= ENST00000295550 NM_004369.3 523 Ctg/Ttg 0 +DENND2D UCSF GRCh37 1 111740573 111740573 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 40 20 48 0 ENST00000357640.4:c.395G>A p.Ser132Asn p.S132N ENST00000357640 NM_024901.4 132 aGc/aAc 0 +HIST1H2AH UCSF GRCh37 6 27115070 27115070 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Pri Untested WXS Illumina HiSeq 100 56 280 0 ENST00000377459.1:c.163G>C p.Val55Leu p.V55L ENST00000377459 NM_080596.2 55 Gtg/Ctg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 55 41 126 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +INPPL1 UCSF GRCh37 11 71948227 71948227 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Pri Untested WXS Illumina HiSeq 96 56 223 0 ENST00000298229.2:c.2939G>C p.Ser980Thr p.S980T ENST00000298229 NM_001567.3 980 aGc/aCc 0 +KDM5A UCSF GRCh37 12 416215 416215 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Pri Untested WXS Illumina HiSeq 275 110 339 0 ENST00000399788.2:c.3971T>C p.Val1324Ala p.V1324A ENST00000399788 NM_001042603.1 1324 gTg/gCg 0 +KIAA0020 UCSF GRCh37 9 2837245 2837245 + missense_variant Missense_Mutation SNP T T A NOVEL P21_Pri Untested WXS Illumina HiSeq 223 235 542 0 ENST00000397885.2:c.239A>T p.Asn80Ile p.N80I ENST00000397885 NM_014878.4 80 aAc/aTc 0 +KIF6 UCSF GRCh37 6 39563952 39563952 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Pri Untested WXS Illumina HiSeq 61 30 98 0 ENST00000287152.7:c.724C>T p.Arg242Ter p.R242* ENST00000287152 NM_145027.4 242 Cga/Tga 0 +LTB4R UCSF GRCh37 14 24785606 24785606 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 15 6 21 0 ENST00000396789.4:c.749C>T p.Ala250Val p.A250V ENST00000396789 NM_181657.3 250 gCc/gTc 0 +NBPF10 UCSF GRCh37 1 145327548 145327548 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Pri Untested WXS Illumina HiSeq 47 11 17 0 ENST00000342960.5:c.4105A>G p.Asn1369Asp p.N1369D ENST00000342960 NM_001039703.5 1369 Aat/Gat 0 +NECAP2 UCSF GRCh37 1 16767274 16767274 + synonymous_variant Silent SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 45 8 103 0 ENST00000443980.2:c.18C>T p.Tyr6= p.Y6= ENST00000443980 NM_001145277.1 6 taC/taT 0 +NPY UCSF GRCh37 7 24324899 24324899 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Pri Untested WXS Illumina HiSeq 39 19 106 0 ENST00000407573.1:c.40C>G p.Leu14Val p.L14V ENST00000407573 14 Ctc/Gtc 0 +PIK3AP1 UCSF GRCh37 10 98405415 98405415 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Pri somatic WXS Sanger Illumina HiSeq 67 16 144 0 ENST00000339364.5:c.1190C>T p.Thr397Met p.T397M ENST00000339364 NM_152309.2 397 aCg/aTg 0 +RAP1GAP2 UCSF GRCh37 17 2908700 2908700 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Pri Untested WXS Illumina HiSeq 216 115 544 0 ENST00000254695.8:c.1238G>T p.Gly413Val p.G413V ENST00000254695 NM_015085.4 413 gGt/gTt 0 +SCAF4 UCSF GRCh37 21 33058004 33058004 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Pri Untested WXS Illumina HiSeq 34 23 62 0 ENST00000286835.7:c.2086C>T p.Gln696Ter p.Q696* ENST00000286835 NM_020706.2 696 Cag/Tag 0 +SPTBN4 UCSF GRCh37 19 41019235 41019235 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Pri Untested WXS Illumina HiSeq 14 5 24 0 ENST00000352632.3:c.2539C>A p.Pro847Thr p.P847T ENST00000352632 847 Cca/Aca 0 +TBX2 UCSF GRCh37 17 59479224 59479224 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Pri Untested WXS Illumina HiSeq 52 8 116 0 ENST00000240328.3:c.575G>T p.Ser192Ile p.S192I ENST00000240328 NM_005994.3 192 aGc/aTc 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Pri somatic WXS Sanger Illumina HiSeq 52 40 129 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TP53 UCSF GRCh37 17 7578388 7578388 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Pri Untested WXS Illumina HiSeq 46 31 127 0 ENST00000269305.4:c.542G>C p.Arg181Pro p.R181P ENST00000269305 NM_001126112.2 181 cGc/cCc 0 +TRDN UCSF GRCh37 6 123824996 123824996 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P21_Pri Untested WXS Illumina HiSeq 29 0 ENST00000398178.3:c.661del p.Glu221LysfsTer2 p.E221Kfs*2 ENST00000398178 NM_006073.3 221 Gaa/aa 0 +UNC5B UCSF GRCh37 10 73051501 73051501 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Pri Untested WXS Illumina HiSeq 32 7 88 0 ENST00000335350.6:c.1607G>C p.Gly536Ala p.G536A ENST00000335350 NM_170744.4 536 gGc/gCc 0 +UNC5B UCSF GRCh37 10 73051475 73051475 + synonymous_variant Silent SNP C C T NOVEL P21_Pri Untested WXS Illumina HiSeq 51 9 104 0 ENST00000335350.6:c.1581C>T p.Ala527= p.A527= ENST00000335350 NM_170744.4 527 gcC/gcT 0 +A2ML1 UCSF GRCh37 12 9001452 9001452 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 368 58 422 0 ENST00000299698.7:c.1970G>A p.Arg657His p.R657H ENST00000299698 NM_144670.4 657 cGt/cAt 0 +AADACL3 UCSF GRCh37 1 12785370 12785370 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 241 63 313 0 ENST00000359318.5:c.460G>A p.Asp154Asn p.D154N ENST00000359318 NM_001103170.1 154 Gat/Aat 0 +ABCB4 UCSF GRCh37 7 87068997 87068997 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 101 39 179 0 ENST00000265723.4:c.1717G>T p.Ala573Ser p.A573S ENST00000265723 NM_000443.3 573 Gca/Tca 0 +ABCC1 UCSF GRCh37 16 16184294 16184294 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 48 11 72 0 ENST00000399410.3:c.2493C>T p.Tyr831= p.Y831= ENST00000399410 NM_004996.3 831 taC/taT 0 +ABR UCSF GRCh37 17 995003 995003 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 135 26 188 1 ENST00000302538.5:c.433G>A p.Asp145Asn p.D145N ENST00000302538 NM_021962.3 145 Gac/Aac 0 +ABR UCSF GRCh37 17 914089 914089 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 28 181 0 ENST00000302538.5:c.2116C>T p.Leu706= p.L706= ENST00000302538 NM_021962.3 706 Ctg/Ttg 0 +ACACA UCSF GRCh37 17 35598915 35598915 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 109 22 118 0 ENST00000353139.5:c.2986G>A p.Glu996Lys p.E996K ENST00000353139 NM_198834.1 996 Gaa/Aaa 0 +ACBD4 UCSF GRCh37 17 43214454 43214454 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 74 17 110 0 ENST00000431281.1:c.363G>A p.Gln121= p.Q121= ENST00000431281 NM_001135704.1 121 caG/caA 0 +ACE UCSF GRCh37 17 61574338 61574338 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 34 6 49 0 ENST00000290866.4:c.3683C>T p.Pro1228Leu p.P1228L ENST00000290866 NM_000789.3 1228 cCg/cTg 0 +ACO1 UCSF GRCh37 9 32431790 32431790 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 26 127 0 ENST00000309951.6:c.1800G>A p.Glu600= p.E600= ENST00000309951 NM_002197.2 600 gaG/gaA 0 +ACRC UCSF GRCh37 X 70832774 70832774 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 43 7 46 0 ENST00000373695.1:c.2018C>T p.Ser673Phe p.S673F ENST00000373695 673 tCt/tTt 0 +ACTL7B UCSF GRCh37 9 111617807 111617807 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 84 55 151 0 ENST00000374667.3:c.404G>A p.Arg135His p.R135H ENST00000374667 NM_006686.3 135 cGc/cAc 0 +ACTR1A UCSF GRCh37 10 104241629 104241629 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 126 39 258 0 ENST00000369905.4:c.952G>A p.Val318Met p.V318M ENST00000369905 NM_005736.3 318 Gtg/Atg 0 +ACTR8 UCSF GRCh37 3 53916017 53916017 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 14 6 34 0 ENST00000335754.3:c.112T>C p.Ser38Pro p.S38P ENST00000335754 NM_022899.4 38 Tcg/Ccg 0 +ADAMTS15 UCSF GRCh37 11 130318956 130318956 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 27 19 93 0 ENST00000299164.2:c.88C>T p.Arg30Ter p.R30* ENST00000299164 NM_139055.2 30 Cga/Tga 0 +ADAP1 UCSF GRCh37 7 938844 938844 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 15 142 0 ENST00000265846.5:c.922G>T p.Val308Leu p.V308L ENST00000265846 NM_006869.2 308 Gtg/Ttg 0 +ADCY9 UCSF GRCh37 16 4016763 4016763 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 280 79 526 0 ENST00000294016.3:c.3075G>A p.Arg1025= p.R1025= ENST00000294016 NM_001116.3 1025 cgG/cgA 0 +ADNP UCSF GRCh37 20 49509195 49509195 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 194 60 286 0 ENST00000396029.3:c.2056C>T p.His686Tyr p.H686Y ENST00000396029 NM_015339.2 686 Cac/Tac 0 +AGAP3 UCSF GRCh37 7 150839618 150839618 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 85 10 107 0 ENST00000397238.2:c.2170C>T p.Pro724Ser p.P724S ENST00000397238 NM_031946.5 724 Cct/Tct 0 +AGBL1 UCSF GRCh37 15 87531263 87531263 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 412 96 492 0 ENST00000441037.2:c.3129C>T p.Tyr1043= p.Y1043= ENST00000441037 NM_152336.2 1043 taC/taT 0 +AGBL3 UCSF GRCh37 7 134719029 134719029 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 37 195 0 ENST00000436302.2:c.687C>T p.Thr229= p.T229= ENST00000436302 NM_178563.3 229 acC/acT 0 +AGPAT5 UCSF GRCh37 8 6605321 6605321 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 114 30 123 0 ENST00000285518.6:c.717G>A p.Gly239= p.G239= ENST00000285518 NM_018361.3 239 ggG/ggA 0 +AGTR1 UCSF GRCh37 3 148458912 148458912 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 37 134 0 ENST00000542281.1:c.90G>A p.Met30Ile p.M30I ENST00000542281 NM_031850.3 30 atG/atA 0 +AHNAK UCSF GRCh37 11 62300649 62300649 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 125 19 164 0 ENST00000378024.4:c.1240G>A p.Glu414Lys p.E414K ENST00000378024 NM_001620.2 414 Gaa/Aaa 0 +AHNAK2 UCSF GRCh37 14 105414940 105414940 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 400 153 852 0 ENST00000333244.5:c.6848G>A p.Ser2283Asn p.S2283N ENST00000333244 NM_138420.2 2283 aGc/aAc 0 +AHNAK2 UCSF GRCh37 14 105418590 105418590 + synonymous_variant Silent SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 354 125 656 0 ENST00000333244.5:c.3198C>G p.Leu1066= p.L1066= ENST00000333244 NM_138420.2 1066 ctC/ctG 0 +AKAP13 UCSF GRCh37 15 86284312 86284312 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 30 12 71 0 ENST00000361243.2:c.7656C>T p.Asp2552= p.D2552= ENST00000361243 NM_006738.5 2552 gaC/gaT 0 +AKAP6 UCSF GRCh37 14 33046434 33046434 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 120 23 151 0 ENST00000280979.4:c.2455C>T p.Leu819= p.L819= ENST00000280979 NM_004274.4 819 Ctg/Ttg 0 +AKAP9 UCSF GRCh37 7 91631287 91631287 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 11 113 0 ENST00000356239.3:c.2056G>A p.Asp686Asn p.D686N ENST00000356239 NM_147185.2 686 Gac/Aac 0 +AKT2 UCSF GRCh37 19 40747844 40747844 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 48 17 84 0 ENST00000392038.2:c.573+1G>A p.X191_splice ENST00000392038 NM_001626.4 0 +ALDH3B1 UCSF GRCh37 11 67790122 67790122 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 64 11 95 0 ENST00000539229.1:c.1003G>A p.Gly335Arg p.G335R ENST00000539229 NM_001161473.1 335 Ggg/Agg 0 +ALDH6A1 UCSF GRCh37 14 74539242 74539242 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 30 154 0 ENST00000553458.1:c.184C>T p.Pro62Ser p.P62S ENST00000553458 NM_001278593.1 62 Cca/Tca 0 +ALG12 UCSF GRCh37 22 50307094 50307094 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 39 196 0 ENST00000330817.6:c.234C>T p.Ser78= p.S78= ENST00000330817 NM_024105.3 78 tcC/tcT 0 +ALG13 UCSF GRCh37 X 111003111 111003111 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 100 80 172 1 ENST00000394780.3:c.3298C>T p.Pro1100Ser p.P1100S ENST00000394780 NM_001257231.1 1100 Cca/Tca 0 +ALK UCSF GRCh37 2 29430102 29430102 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 54 22 85 1 ENST00000389048.3:c.3873G>A p.Leu1291= p.L1291= ENST00000389048 NM_004304.4 1291 ctG/ctA 0 +ALMS1 UCSF GRCh37 2 73786249 73786249 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 68 12 112 0 ENST00000264448.6:c.10361C>T p.Ser3454Phe p.S3454F ENST00000264448 NM_015120.4 3454 tCc/tTc 0 +ALOX15 UCSF GRCh37 17 4542834 4542834 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 54 12 77 1 ENST00000570836.1:c.228G>A p.Trp76Ter p.W76* ENST00000570836 76 tgG/tgA 0 +ALOX5 UCSF GRCh37 10 45907762 45907762 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 91 23 138 0 ENST00000374391.2:c.554+1G>A p.X185_splice ENST00000374391 NM_000698.3 0 +ALS2 UCSF GRCh37 2 202589068 202589068 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 141 43 248 1 ENST00000264276.6:c.3462G>A p.Gln1154= p.Q1154= ENST00000264276 NM_020919.3 1154 caG/caA 0 +ALS2 UCSF GRCh37 2 202598137 202598137 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 40 18 49 0 ENST00000264276.6:c.2442G>A p.Glu814= p.E814= ENST00000264276 NM_020919.3 814 gaG/gaA 0 +AMOTL2 UCSF GRCh37 3 134078188 134078188 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 78 13 122 0 ENST00000249883.5:c.2041G>A p.Gly681Ser p.G681S ENST00000249883 NM_016201.3 681 Ggc/Agc 0 +ANGPTL1 UCSF GRCh37 1 178822772 178822772 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 155 41 179 0 ENST00000234816.2:c.974C>T p.Thr325Ile p.T325I ENST00000234816 NM_004673.3 325 aCa/aTa 0 +ANK1 UCSF GRCh37 8 41550641 41550641 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 96 31 120 0 ENST00000265709.8:c.3734C>T p.Thr1245Ile p.T1245I ENST00000265709 NM_001142446.1 1245 aCc/aTc 0 +AP2A1 UCSF GRCh37 19 50304848 50304848 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 82 20 140 0 ENST00000359032.5:c.1755C>T p.Thr585= p.T585= ENST00000359032 NM_014203.2 585 acC/acT 0 +AP2B1 UCSF GRCh37 17 33984689 33984689 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 97 30 139 0 ENST00000312678.8:c.1868C>T p.Ser623Phe p.S623F ENST00000312678 NM_001030006.1 623 tCt/tTt 0 +AP3B1 UCSF GRCh37 5 77396850 77396850 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 22 3 19 0 ENST00000255194.6:c.2398-1G>A p.X800_splice ENST00000255194 0 +APC UCSF GRCh37 5 112174811 112174811 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 164 49 209 0 ENST00000257430.4:c.3520G>A p.Asp1174Asn p.D1174N ENST00000257430 NM_000038.5 1174 Gat/Aat 0 +ARHGAP15 UCSF GRCh37 2 144314015 144314015 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 159 43 262 0 ENST00000295095.6:c.964C>T p.Leu322= p.L322= ENST00000295095 NM_018460.3 322 Ctg/Ttg 0 +ARHGAP31 UCSF GRCh37 3 119134420 119134420 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 78 25 111 0 ENST00000264245.4:c.3644C>T p.Pro1215Leu p.P1215L ENST00000264245 NM_020754.2 1215 cCc/cTc 0 +ARHGAP32 UCSF GRCh37 11 128840445 128840445 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 107 26 157 0 ENST00000310343.9:c.4621G>A p.Gly1541Arg p.G1541R ENST00000310343 NM_001142685.1 1541 Gga/Aga 0 +ARHGEF2 UCSF GRCh37 1 155920170 155920170 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 101 33 160 1 ENST00000361247.4:c.2807G>A p.Arg936Gln p.R936Q ENST00000361247 NM_001162384.1 936 cGg/cAg 0 +ARL13A UCSF GRCh37 X 100240728 100240728 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 159 114 345 0 ENST00000450049.2:c.203C>T p.Ser68Phe p.S68F ENST00000450049 NM_001162491.1 68 tCc/tTc 0 +ARMC5 UCSF GRCh37 16 31478036 31478036 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 16 3 22 0 ENST00000268314.4:c.2634C>T p.Pro878= p.P878= ENST00000268314 NM_001105247.1 878 ccC/ccT 0 +ARNT UCSF GRCh37 1 150788827 150788827 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 19 62 0 ENST00000358595.5:c.1858C>T p.Gln620Ter p.Q620* ENST00000358595 NM_178427.2 620 Cag/Tag 0 +ARPM1 UCSF GRCh37 3 169485464 169485464 + missense_variant Missense_Mutation SNP G G A snp132_rs55656133 P21_Rec Untested WXS Illumina HiSeq 237 56 287 1 ENST00000330368.2:c.875C>T p.Ser292Phe p.S292F ENST00000330368 NM_032487.4 292 tCc/tTc 0 +ASCC3 UCSF GRCh37 6 101247327 101247327 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 41 17 106 0 ENST00000369162.2:c.1249G>A p.Ala417Thr p.A417T ENST00000369162 NM_006828.2 417 Gca/Aca 0 +ASXL1 UCSF GRCh37 20 31024066 31024066 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 153 33 212 1 ENST00000375687.4:c.3551C>T p.Thr1184Ile p.T1184I ENST00000375687 NM_015338.5 1184 aCa/aTa 0 +ASXL1 UCSF GRCh37 20 31023784 31023784 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 224 77 359 0 ENST00000375687.4:c.3269G>A p.Arg1090Lys p.R1090K ENST00000375687 NM_015338.5 1090 aGa/aAa 0 +ATG4A UCSF GRCh37 X 107381120 107381120 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 27 183 275 0 ENST00000372232.3:c.634G>A p.Gly212Ser p.G212S ENST00000372232 NM_052936.3 212 Ggc/Agc 0 +ATP13A4 UCSF GRCh37 3 193156272 193156272 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 46 30 122 0 ENST00000342695.4:c.2664C>T p.His888= p.H888= ENST00000342695 NM_032279.2 888 caC/caT 0 +ATP1A2 UCSF GRCh37 1 160105700 160105700 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 221 33 268 1 ENST00000361216.3:c.2356C>T p.Pro786Ser p.P786S ENST00000361216 NM_000702.3 786 Ccc/Tcc 0 +ATP5L UCSF GRCh37 11 118279715 118279715 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 15 9 35 0 ENST00000300688.3:c.214G>A p.Glu72Lys p.E72K ENST00000300688 NM_006476.4 72 Gaa/Aaa 0 +ATP5S UCSF GRCh37 14 50789230 50789230 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 12 167 0 ENST00000311459.7:c.154G>A p.Val52Met p.V52M ENST00000311459 NM_001003803.2 52 Gtg/Atg 0 +ATP6V1B1 UCSF GRCh37 2 71187101 71187101 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 71 32 159 0 ENST00000234396.4:c.478C>T p.Pro160Ser p.P160S ENST00000234396 NM_001692.3 160 Ccc/Tcc 0 +ATRX UCSF GRCh37 X 76845402 76845403 + frameshift_variant Frame_Shift_Del DEL AA AA - NOVEL P21_Rec Untested WXS Illumina HiSeq 23 0 ENST00000373344.5:c.6118_6119del p.Phe2040GlnfsTer11 p.F2040Qfs*11 ENST00000373344 NM_000489.3 2040 TTc/c 0 +B4GALNT1 UCSF GRCh37 12 58024853 58024853 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 55 285 0 ENST00000341156.4:c.400G>A p.Asp134Asn p.D134N ENST00000341156 NM_001478.4 134 Gac/Aac 0 +B7H6 UCSF GRCh37 11 17388734 17388734 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 94 57 286 1 ENST00000338965.4:c.600C>T p.Ile200= p.I200= ENST00000338965 NM_001202439.1 200 atC/atT 0 +BAAT UCSF GRCh37 9 104130406 104130406 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 52 20 78 0 ENST00000259407.2:c.665C>T p.Pro222Leu p.P222L ENST00000259407 NM_001127610.1 222 cCa/cTa 0 +BAG3 UCSF GRCh37 10 121429613 121429613 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 42 27 165 0 ENST00000369085.3:c.431C>T p.Thr144Ile p.T144I ENST00000369085 NM_004281.3 144 aCc/aTc 0 +BAHCC1 UCSF GRCh37 17 79410157 79410157 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 30 9 61 0 ENST00000307745.7:c.1782G>A p.Met594Ile p.M594I ENST00000307745 594 atG/atA 0 +BARD1 UCSF GRCh37 2 215645709 215645709 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 103 28 196 0 ENST00000260947.4:c.889G>A p.Val297Ile p.V297I ENST00000260947 NM_000465.2 297 Gta/Ata 0 +BARD1 UCSF GRCh37 2 215593469 215593469 + synonymous_variant Silent SNP G G A snp132_rs13389324 P21_Rec Untested WXS Illumina HiSeq 78 27 133 0 ENST00000260947.4:c.2265C>T p.Val755= p.V755= ENST00000260947 NM_000465.2 755 gtC/gtT 0 +BATF2 UCSF GRCh37 11 64756758 64756758 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 65 16 85 0 ENST00000301887.4:c.668C>T p.Pro223Leu p.P223L ENST00000301887 NM_138456.3 223 cCc/cTc 0 +BBS1 UCSF GRCh37 11 66283345 66283345 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 18 120 0 ENST00000318312.7:c.532G>A p.Glu178Lys p.E178K ENST00000318312 NM_024649.4 178 Gag/Aag 0 +BCR UCSF GRCh37 22 23523778 23523778 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 96 28 158 0 ENST00000305877.8:c.631G>A p.Glu211Lys p.E211K ENST00000305877 NM_004327.3 211 Gag/Aag 0 +BDH2 UCSF GRCh37 4 104016418 104016418 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 57 37 120 0 ENST00000296424.4:c.93C>T p.Ala31= p.A31= ENST00000296424 NM_020139.3 31 gcC/gcT 0 +BICC1 UCSF GRCh37 10 60556125 60556125 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 108 29 191 0 ENST00000373886.3:c.1205G>A p.Arg402Gln p.R402Q ENST00000373886 NM_001080512.1 402 cGa/cAa 0 +BIRC6 UCSF GRCh37 2 32656086 32656086 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 147 49 324 0 ENST00000421745.2:c.3176C>T p.Pro1059Leu p.P1059L ENST00000421745 NM_016252.3 1059 cCt/cTt 0 +BMI1 UCSF GRCh37 10 22615405 22615405 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 257 53 231 0 ENST00000376663.3:c.27C>T p.Ile9= p.I9= ENST00000376663 NM_005180.8 9 atC/atT 0 +BOD1L UCSF GRCh37 4 13605438 13605438 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 404 107 475 1 ENST00000040738.5:c.3086G>A p.Ser1029Asn p.S1029N ENST00000040738 NM_148894.2 1029 aGt/aAt 0 +BPNT1 UCSF GRCh37 1 220236275 220236275 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 107 26 125 0 ENST00000469520.2:c.496G>A p.Gly166Arg p.G166R ENST00000469520 166 Ggg/Agg 0 +BPTF UCSF GRCh37 17 65850839 65850839 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 114 18 112 0 ENST00000306378.6:c.1397G>A p.Ser466Asn p.S466N ENST00000306378 NM_182641.3 466 aGt/aAt 0 +BRCA2 UCSF GRCh37 13 32907452 32907452 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 4 78 0 ENST00000380152.3:c.1837C>T p.Leu613= p.L613= ENST00000380152 613 Cta/Tta 0 +BRIP1 UCSF GRCh37 17 59871087 59871087 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 68 22 91 0 ENST00000259008.2:c.1344G>A p.Trp448Ter p.W448* ENST00000259008 NM_032043.2 448 tgG/tgA 0 +BTN2A1 UCSF GRCh37 6 26468761 26468761 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 485 74 352 1 ENST00000312541.5:c.1568C>T p.Thr523Ile p.T523I ENST00000312541 NM_007049.4 523 aCc/aTc 0 +BTNL3 UCSF GRCh37 5 180419994 180419994 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 77 61 272 0 ENST00000342868.6:c.231G>A p.Gln77= p.Q77= ENST00000342868 NM_197975.2 77 caG/caA 0 +BTNL8 UCSF GRCh37 5 180335635 180335635 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 26 187 0 ENST00000340184.4:c.99G>A p.Gly33= p.G33= ENST00000340184 NM_001040462.2 33 ggG/ggA 0 +BUB3 UCSF GRCh37 10 124919988 124919988 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 60 45 212 0 ENST00000368865.4:c.483G>A p.Val161= p.V161= ENST00000368865 NM_004725.3 161 gtG/gtA 0 +C11orf30 UCSF GRCh37 11 76207340 76207340 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 171 61 229 0 ENST00000529032.1:c.1190T>C p.Leu397Pro p.L397P ENST00000529032 397 cTt/cCt 0 +C11orf91 UCSF GRCh37 11 33719981 33719981 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 29 21 101 0 ENST00000379011.4:c.576C>T p.Leu192= p.L192= ENST00000379011 NM_001166692.1 192 ctC/ctT 0 +C12orf4 UCSF GRCh37 12 4609359 4609359 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 149 21 121 0 ENST00000261250.3:c.1385C>T p.Thr462Ile p.T462I ENST00000261250 NM_020374.2 462 aCc/aTc 0 +C15orf43 UCSF GRCh37 15 45258369 45258369 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 29 10 30 0 ENST00000340827.3:c.362C>T p.Thr121Ile p.T121I ENST00000340827 NM_152448.2 121 aCa/aTa 0 +C17orf101 UCSF GRCh37 17 80373330 80373330 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 165 47 221 0 ENST00000329197.5:c.248G>A p.Gly83Glu p.G83E ENST00000329197 83 gGg/gAg 0 +C1orf112 UCSF GRCh37 1 169819407 169819407 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 42 8 44 0 ENST00000286031.6:c.2165G>A p.Gly722Glu p.G722E ENST00000286031 NM_018186.2 722 gGa/gAa 0 +C1QC UCSF GRCh37 1 22974090 22974090 + synonymous_variant Silent SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 182 59 340 0 ENST00000374639.3:c.552C>G p.Arg184= p.R184= ENST00000374639 NM_001114101.1 184 cgC/cgG 0 +C20orf194 UCSF GRCh37 20 3236766 3236766 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 120 25 171 0 ENST00000252032.9:c.3147C>T p.Asp1049= p.D1049= ENST00000252032 NM_001009984.2 1049 gaC/gaT 0 +C2CD3 UCSF GRCh37 11 73785467 73785467 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 125 28 149 0 ENST00000313663.7:c.4782C>T p.Leu1594= p.L1594= ENST00000313663 NM_015531.4 1594 ctC/ctT 0 +C2orf18 UCSF GRCh37 2 26997143 26997143 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 82 19 138 0 ENST00000344420.5:c.102G>A p.Glu34= p.E34= ENST00000344420 NM_017877.3 34 gaG/gaA 0 +C3orf39 UCSF GRCh37 3 43122166 43122166 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 105 53 208 1 ENST00000344697.2:c.758C>A p.Pro253Gln p.P253Q ENST00000344697 NM_032806.5 253 cCg/cAg 0 +C3orf39 UCSF GRCh37 3 43121571 43121571 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 33 131 0 ENST00000344697.2:c.1353G>A p.Lys451= p.K451= ENST00000344697 NM_032806.5 451 aaG/aaA 0 +C6orf138 UCSF GRCh37 6 47847449 47847449 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 521 67 388 0 ENST00000339488.4:c.1131G>A p.Leu377= p.L377= ENST00000339488 NM_001013732.3 377 ttG/ttA 0 +C9orf172 UCSF GRCh37 9 139739679 139739679 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 27 10 33 0 ENST00000436881.1:c.813C>T p.Pro271= p.P271= ENST00000436881 NM_001080482.2 271 ccC/ccT 0 +C9orf84 UCSF GRCh37 9 114490030 114490030 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 161 33 146 0 ENST00000374287.3:c.1525G>A p.Glu509Lys p.E509K ENST00000374287 509 Gaa/Aaa 0 +C9orf96 UCSF GRCh37 9 136270002 136270002 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 98 28 166 0 ENST00000371957.3:c.1822C>T p.Pro608Ser p.P608S ENST00000371957 NM_153710.4 608 Ccg/Tcg 0 +CA7 UCSF GRCh37 16 66886645 66886645 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 10 98 0 ENST00000338437.2:c.547C>T p.Pro183Ser p.P183S ENST00000338437 NM_005182.2 183 Ccc/Tcc 0 +CAD UCSF GRCh37 2 27447343 27447343 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 110 17 152 0 ENST00000264705.4:c.1239C>T p.Asp413= p.D413= ENST00000264705 NM_004341.3 413 gaC/gaT 0 +CAMKK2 UCSF GRCh37 12 121711942 121711942 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 19 9 23 0 ENST00000324774.5:c.388C>T p.Pro130Ser p.P130S ENST00000324774 NM_006549.3 130 Ccc/Tcc 0 +CAP2 UCSF GRCh37 6 17551772 17551772 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 215 34 194 0 ENST00000229922.2:c.1287C>T p.Asp429= p.D429= ENST00000229922 NM_006366.2 429 gaC/gaT 0 +CAPN12 UCSF GRCh37 19 39228950 39228950 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 31 22 53 0 ENST00000328867.4:c.928G>A p.Asp310Asn p.D310N ENST00000328867 NM_144691.3 310 Gat/Aat 0 +CAPN9 UCSF GRCh37 1 230891097 230891097 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 86 20 118 0 ENST00000271971.2:c.228C>T p.Asn76= p.N76= ENST00000271971 NM_006615.2 76 aaC/aaT 0 +CARD6 UCSF GRCh37 5 40841605 40841605 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 107 39 144 0 ENST00000254691.5:c.121G>A p.Glu41Lys p.E41K ENST00000254691 NM_032587.3 41 Gag/Aag 0 +CASD1 UCSF GRCh37 7 94168278 94168278 + splice_acceptor_variant Splice_Site SNP G G A snp132_rs115186017 P21_Rec Untested WXS Illumina HiSeq 51 21 65 0 ENST00000297273.4:c.1267-1G>A p.X423_splice ENST00000297273 NM_022900.4 0 +CASKIN2 UCSF GRCh37 17 73499007 73499007 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 9 57 0 ENST00000321617.3:c.2148C>T p.Ala716= p.A716= ENST00000321617 NM_020753.4 716 gcC/gcT 0 +CASZ1 UCSF GRCh37 1 10720283 10720283 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 77 31 103 0 ENST00000377022.3:c.816C>T p.Thr272= p.T272= ENST00000377022 NM_001079843.2 272 acC/acT 0 +CAT UCSF GRCh37 11 34472578 34472578 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 116 63 275 0 ENST00000241052.4:c.282C>T p.Tyr94= p.Y94= ENST00000241052 NM_001752.3 94 taC/taT 0 +CBFA2T2 UCSF GRCh37 20 32199107 32199107 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 168 51 229 0 ENST00000346541.3:c.413G>A p.Gly138Glu p.G138E ENST00000346541 NM_005093.3 138 gGg/gAg 0 +CCDC108 UCSF GRCh37 2 219888018 219888018 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 17 6 45 0 ENST00000341552.5:c.2731C>T p.Leu911= p.L911= ENST00000341552 NM_194302.3 911 Ctg/Ttg 0 +CCDC132 UCSF GRCh37 7 92979301 92979301 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 16 117 0 ENST00000305866.5:c.2419G>A p.Glu807Lys p.E807K ENST00000305866 NM_017667.3 807 Gaa/Aaa 0 +CCDC135 UCSF GRCh37 16 57764849 57764849 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 106 31 159 0 ENST00000360716.3:c.2398C>T p.Gln800Ter p.Q800* ENST00000360716 800 Cag/Tag 0 +CCDC86 UCSF GRCh37 11 60609982 60609982 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 135 28 164 0 ENST00000227520.5:c.385C>T p.Gln129Ter p.Q129* ENST00000227520 NM_024098.3 129 Cag/Tag 0 +CCDC97 UCSF GRCh37 19 41825651 41825651 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 52 16 76 0 ENST00000269967.3:c.675C>T p.Leu225= p.L225= ENST00000269967 NM_052848.1 225 ctC/ctT 0 +CCND2 UCSF GRCh37 12 4385225 4385225 + splice_region_variant,non_coding_transcript_exon_variant Splice_Region SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 143 24 143 0 ENST00000539135.1:n.126G>A p.X42_splice ENST00000539135 0 +CCNJ UCSF GRCh37 10 97816568 97816568 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 82 40 141 0 ENST00000465148.2:c.391G>A p.Glu131Lys p.E131K ENST00000465148 131 Gaa/Aaa 0 +CCT8 UCSF GRCh37 21 30439053 30439053 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 106 20 114 0 ENST00000286788.4:c.608G>A p.Arg203Lys p.R203K ENST00000286788 NM_006585.2 203 aGa/aAa 0 +CD163L1 UCSF GRCh37 12 7559158 7559158 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 251 61 322 0 ENST00000313599.3:c.1057C>T p.His353Tyr p.H353Y ENST00000313599 353 Cat/Tat 0 +CD1B UCSF GRCh37 1 158299756 158299756 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.006,1000g2011may_all_0.01772,snp132_rs62642467 P21_Rec Untested WXS Illumina HiSeq 354 95 446 0 ENST00000368168.3:c.493C>T p.Leu165= p.L165= ENST00000368168 NM_001764.2 165 Cta/Tta 0 +CD276 UCSF GRCh37 15 73995123 73995123 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 23 66 0 ENST00000318443.5:c.429G>A p.Ser143= p.S143= ENST00000318443 NM_001024736.1 143 tcG/tcA 0 +CDAN1 UCSF GRCh37 15 43023168 43023168 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 48 222 0 ENST00000356231.3:c.1962C>T p.Pro654= p.P654= ENST00000356231 NM_138477.2 654 ccC/ccT 0 +CDC16 UCSF GRCh37 13 115002355 115002355 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 42 18 95 0 ENST00000360383.3:c.185C>T p.Ser62Leu p.S62L ENST00000360383 NM_001078645.1 62 tCa/tTa 0 +CDC40 UCSF GRCh37 6 110541060 110541060 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 37 158 0 ENST00000368932.1:c.1328G>A p.Arg443Lys p.R443K ENST00000368932 443 aGa/aAa 0 +CDC42EP1 UCSF GRCh37 22 37962634 37962634 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 21 106 0 ENST00000249014.4:c.278G>A p.Gly93Glu p.G93E ENST00000249014 NM_152243.2 93 gGg/gAg 0 +CDH11 UCSF GRCh37 16 64981800 64981800 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 180 50 266 0 ENST00000268603.4:c.2097G>A p.Glu699= p.E699= ENST00000268603 NM_001797.2 699 gaG/gaA 0 +CDH12 UCSF GRCh37 5 21752025 21752025 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 138 38 212 0 ENST00000382254.1:c.2206C>T p.Leu736= p.L736= ENST00000382254 NM_004061.3 736 Ctg/Ttg 0 +CDH23 UCSF GRCh37 10 73405665 73405665 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 80 28 200 0 ENST00000224721.6:c.1233G>A p.Gln411= p.Q411= ENST00000224721 NM_022124.5 411 caG/caA 0 +CDH23 UCSF GRCh37 10 73544108 73544108 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 66 29 160 0 ENST00000224721.6:c.5448G>A p.Arg1816= p.R1816= ENST00000224721 NM_022124.5 1816 cgG/cgA 0 +CDHR3 UCSF GRCh37 7 105672892 105672892 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 108 38 167 0 ENST00000317716.9:c.2407G>A p.Asp803Asn p.D803N ENST00000317716 NM_152750.4 803 Gat/Aat 0 +CDKN1B UCSF GRCh37 12 12870849 12870849 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 39 0 ENST00000228872.4:c.78del p.Ser27ArgfsTer15 p.S27Rfs*15 ENST00000228872 NM_004064.3 26 Ccc/cc 0 +CDKN2A UCSF GRCh37 9 21974770 21974770 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 12 0 ENST00000304494.5:c.57del p.Ala20ArgfsTer6 p.A20Rfs*6 ENST00000304494 NM_000077.4 19 gcC/gc 0 +CDON UCSF GRCh37 11 125851126 125851126 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 98 12 173 0 ENST00000392693.3:c.3094G>A p.Val1032Ile p.V1032I ENST00000392693 NM_001243597.1 1032 Gtt/Att 0 +CDX4 UCSF GRCh37 X 72667505 72667505 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 4 42 63 0 ENST00000373514.2:c.416C>T p.Thr139Met p.T139M ENST00000373514 NM_005193.1 139 aCg/aTg 0 +CELSR3 UCSF GRCh37 3 48696345 48696345 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 60 15 103 0 ENST00000164024.4:c.3723G>A p.Val1241= p.V1241= ENST00000164024 NM_001407.2 1241 gtG/gtA 0 +CENPF UCSF GRCh37 1 214819208 214819208 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 142 18 157 0 ENST00000366955.3:c.6295G>A p.Glu2099Lys p.E2099K ENST00000366955 NM_016343.3 2099 Gag/Aag 0 +CEP350 UCSF GRCh37 1 179961206 179961206 + missense_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 36 7 42 0 ENST00000367607.3:c.245A>T p.Tyr82Phe p.Y82F ENST00000367607 NM_014810.4 82 tAc/tTc 0 +CEP72 UCSF GRCh37 5 620366 620366 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 21 133 0 ENST00000264935.5:c.393C>T p.Leu131= p.L131= ENST00000264935 NM_018140.3 131 ctC/ctT 0 +CEP78 UCSF GRCh37 9 80880305 80880305 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 29 154 0 ENST00000376597.4:c.1646C>T p.Thr549Ile p.T549I ENST00000376597 NM_001098802.1 549 aCa/aTa 0 +CETN2 UCSF GRCh37 X 151997217 151997217 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 40 26 85 0 ENST00000370277.3:c.293C>T p.Ser98Phe p.S98F ENST00000370277 NM_004344.1 98 tCt/tTt 0 +CFHR5 UCSF GRCh37 1 196965270 196965270 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 156 38 189 0 ENST00000256785.4:c.909G>A p.Met303Ile p.M303I ENST00000256785 303 atG/atA 0 +CHCHD7 UCSF GRCh37 8 57129925 57129925 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 52 13 63 0 ENST00000303759.3:c.264G>A p.Val88= p.V88= ENST00000303759 NM_001011667.1 88 gtG/gtA 0 +CHD6 UCSF GRCh37 20 40162013 40162013 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 173 52 209 0 ENST00000373233.3:c.230C>T p.Thr77Ile p.T77I ENST00000373233 NM_032221.4 77 aCa/aTa 0 +CHD9 UCSF GRCh37 16 53357969 53357969 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 312 46 394 0 ENST00000566029.1:c.7808C>T p.Thr2603Ile p.T2603I ENST00000566029 2603 aCt/aTt 0 +CHEK2 UCSF GRCh37 22 29085187 29085187 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 122 30 260 0 ENST00000328354.6:c.1478G>A p.Arg493Lys p.R493K ENST00000328354 NM_007194.3 493 aGa/aAa 0 +CHI3L1 UCSF GRCh37 1 203151876 203151876 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 17 114 0 ENST00000255409.3:c.570C>T p.Asp190= p.D190= ENST00000255409 NM_001276.2 190 gaC/gaT 0 +CHMP7 UCSF GRCh37 8 23114047 23114047 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 226 58 359 0 ENST00000397677.1:c.732G>A p.Leu244= p.L244= ENST00000397677 NM_152272.3 244 ctG/ctA 0 +CHRM5 UCSF GRCh37 15 34356140 34356140 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 216 48 319 0 ENST00000383263.5:c.1222C>G p.Pro408Ala p.P408A ENST00000383263 NM_012125.3 408 Cca/Gca 0 +CHRNA1 UCSF GRCh37 2 175619138 175619138 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 70 25 142 0 ENST00000261007.5:c.424G>A p.Asp142Asn p.D142N ENST00000261007 NM_001039523.2 142 Gat/Aat 0 +CHST9 UCSF GRCh37 18 24604085 24604085 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 29 16 43 0 ENST00000284224.8:c.197G>A p.Arg66Lys p.R66K ENST00000284224 NM_031422.5 66 aGa/aAa 0 +CLCNKA UCSF GRCh37 1 16355325 16355325 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 21 123 0 ENST00000331433.4:c.1038C>T p.His346= p.H346= ENST00000331433 346 caC/caT 0 +CLEC6A UCSF GRCh37 12 8618156 8618156 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 25 169 0 ENST00000382073.3:c.300G>A p.Trp100Ter p.W100* ENST00000382073 NM_001007033.1 100 tgG/tgA 0 +CLK2 UCSF GRCh37 1 155233756 155233756 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 48 187 0 ENST00000361168.5:c.1299C>T p.Asn433= p.N433= ENST00000361168 433 aaC/aaT 0 +CLSPN UCSF GRCh37 1 36230067 36230067 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 136 26 100 1 ENST00000318121.3:c.382G>A p.Val128Met p.V128M ENST00000318121 NM_022111.3 128 Gtg/Atg 0 +CLSTN3 UCSF GRCh37 12 7285717 7285717 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 59 15 82 0 ENST00000266546.6:c.162C>T p.Asp54= p.D54= ENST00000266546 NM_014718.3 54 gaC/gaT 0 +CMAS UCSF GRCh37 12 22218154 22218154 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 210 34 190 0 ENST00000229329.2:c.1214G>A p.Cys405Tyr p.C405Y ENST00000229329 NM_018686.4 405 tGc/tAc 0 +CMYA5 UCSF GRCh37 5 79025325 79025325 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 193 47 194 0 ENST00000446378.2:c.737G>A p.Gly246Glu p.G246E ENST00000446378 NM_153610.3 246 gGa/gAa 0 +CNGA1 UCSF GRCh37 4 47951873 47951873 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 74 21 89 0 ENST00000402813.3:c.483G>A p.Val161= p.V161= ENST00000402813 161 gtG/gtA 0 +CNPY4 UCSF GRCh37 7 99722496 99722496 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 46 217 0 ENST00000262932.3:c.732C>T p.Asp244= p.D244= ENST00000262932 NM_152755.1 244 gaC/gaT 0 +CNR2 UCSF GRCh37 1 24201575 24201575 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 107 27 151 0 ENST00000536471.1:c.533C>T p.Pro178Leu p.P178L ENST00000536471 178 cCc/cTc 0 +CNTN6 UCSF GRCh37 3 1444021 1444021 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 75 29 127 0 ENST00000446702.2:c.2837G>A p.Arg946Lys p.R946K ENST00000446702 946 aGa/aAa 0 +CNTNAP1 UCSF GRCh37 17 40849300 40849300 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 85 16 109 0 ENST00000264638.4:c.3483C>T p.Tyr1161= p.Y1161= ENST00000264638 NM_003632.2 1161 taC/taT 0 +COG8 UCSF GRCh37 16 69366747 69366747 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 127 34 191 0 ENST00000306875.4:c.1452G>A p.Glu484= p.E484= ENST00000306875 NM_032382.4 484 gaG/gaA 0 +COL10A1 UCSF GRCh37 6 116442735 116442735 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 37 5 82 0 ENST00000327673.4:c.544C>T p.Pro182Ser p.P182S ENST00000327673 182 Cct/Tct 0 +COL1A1 UCSF GRCh37 17 48273995 48273995 + missense_variant Missense_Mutation SNP C C T snp132_rs72645334 P21_Rec Untested WXS Illumina HiSeq 370 93 491 0 ENST00000225964.5:c.841G>A p.Gly281Ser p.G281S ENST00000225964 NM_000088.3 281 Ggt/Agt 0 +COL5A3 UCSF GRCh37 19 10108817 10108817 + synonymous_variant Silent SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 270 59 364 0 ENST00000264828.3:c.1119A>G p.Gly373= p.G373= ENST00000264828 NM_015719.3 373 ggA/ggG 0 +COL6A2 UCSF GRCh37 21 47544812 47544812 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 66 17 80 0 ENST00000300527.4:c.1748C>T p.Pro583Leu p.P583L ENST00000300527 NM_001849.3 583 cCc/cTc 0 +COL6A3 UCSF GRCh37 2 238303787 238303787 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 46 23 75 0 ENST00000295550.4:c.152G>A p.Gly51Glu p.G51E ENST00000295550 NM_004369.3 51 gGa/gAa 0 +COL6A3 UCSF GRCh37 2 238275523 238275523 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 106 38 214 0 ENST00000295550.4:c.5307G>A p.Arg1769= p.R1769= ENST00000295550 NM_004369.3 1769 agG/agA 0 +COL6A6 UCSF GRCh37 3 130286093 130286093 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 303 74 365 0 ENST00000358511.6:c.1830C>T p.Ile610= p.I610= ENST00000358511 NM_001102608.1 610 atC/atT 0 +COL6A6 UCSF GRCh37 3 130300508 130300508 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 365 97 443 0 ENST00000358511.6:c.3651C>T p.Ile1217= p.I1217= ENST00000358511 NM_001102608.1 1217 atC/atT 0 +COL9A1 UCSF GRCh37 6 70973001 70973001 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 17 3 29 0 ENST00000357250.6:c.1342-1G>A p.X448_splice ENST00000357250 NM_001851.4 0 +COL9A2 UCSF GRCh37 1 40777380 40777380 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 26 123 0 ENST00000372748.3:c.425C>T p.Pro142Leu p.P142L ENST00000372748 NM_001852.3 142 cCt/cTt 0 +COPA UCSF GRCh37 1 160281759 160281759 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 81 21 128 0 ENST00000368069.3:c.975C>T p.Ala325= p.A325= ENST00000368069 325 gcC/gcT 0 +COPB1 UCSF GRCh37 11 14510097 14510097 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 22 12 62 0 ENST00000249923.3:c.640G>A p.Asp214Asn p.D214N ENST00000249923 NM_016451.4 214 Gat/Aat 0 +COQ2 UCSF GRCh37 4 84191112 84191112 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 83 44 229 1 ENST00000311469.4:c.813G>A p.Trp271Ter p.W271* ENST00000311469 NM_015697.7 271 tgG/tgA 0 +CORO1A UCSF GRCh37 16 30199523 30199523 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 129 18 213 0 ENST00000219150.5:c.1018C>T p.Leu340= p.L340= ENST00000219150 NM_007074.3 340 Ctg/Ttg 0 +CP UCSF GRCh37 3 148899850 148899850 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 126 38 163 0 ENST00000264613.6:c.2496C>T p.Tyr832= p.Y832= ENST00000264613 NM_000096.3 832 taC/taT 0 +CPNE3 UCSF GRCh37 8 87540831 87540831 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 85 19 115 0 ENST00000521271.1:c.58G>T p.Asp20Tyr p.D20Y ENST00000521271 NM_003909.3 20 Gat/Tat 0 +CPNE3 UCSF GRCh37 8 87559997 87559997 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 42 6 40 0 ENST00000521271.1:c.878C>T p.Thr293Ile p.T293I ENST00000521271 NM_003909.3 293 aCt/aTt 0 +CPNE6 UCSF GRCh37 14 24546809 24546809 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 104 48 249 0 ENST00000397016.2:c.1544C>T p.Pro515Leu p.P515L ENST00000397016 NM_001280558.1 515 cCc/cTc 0 +CPNE9 UCSF GRCh37 3 9746480 9746480 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 25 4 29 0 ENST00000383832.3:c.156+1G>A p.X52_splice ENST00000383832 NM_153635.2 0 +CPT1A UCSF GRCh37 11 68540840 68540840 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 102 37 161 0 ENST00000265641.5:c.1633G>A p.Asp545Asn p.D545N ENST00000265641 NM_001876.3 545 Gat/Aat 0 +CRADD UCSF GRCh37 12 94244012 94244012 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 46 11 58 0 ENST00000542893.2:c.565G>A p.Val189Met p.V189M ENST00000542893 189 Gtg/Atg 0 +CREBBP UCSF GRCh37 16 3779333 3779333 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 14 5 24 0 ENST00000262367.5:c.5715C>T p.Pro1905= p.P1905= ENST00000262367 NM_004380.2 1905 ccC/ccT 0 +CRLF3 UCSF GRCh37 17 29112936 29112936 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 81 16 96 0 ENST00000324238.6:c.1072+1G>A p.X358_splice ENST00000324238 NM_015986.3 0 +CRMP1 UCSF GRCh37 4 5827243 5827243 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 105 27 145 0 ENST00000324989.7:c.1947C>T p.His649= p.H649= ENST00000324989 NM_001014809.1 649 caC/caT 0 +CRTC1 UCSF GRCh37 19 18888034 18888034 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 262 100 327 0 ENST00000338797.6:c.1795G>A p.Gly599Arg p.G599R ENST00000338797 NM_001098482.1 599 Ggg/Agg 0 +CSHL1 UCSF GRCh37 17 61987262 61987262 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 242 70 341 0 ENST00000309894.5:c.478G>A p.Glu160Lys p.E160K ENST00000309894 NM_022579.1 160 Gaa/Aaa 0 +CTDP1 UCSF GRCh37 18 77474755 77474755 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 13 5 25 0 ENST00000299543.7:c.1295G>A p.Gly432Asp p.G432D ENST00000299543 NM_001202504.1 432 gGt/gAt 0 +CTLA4 UCSF GRCh37 2 204736188 204736188 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 114 32 179 0 ENST00000302823.3:c.545C>T p.Thr182Ile p.T182I ENST00000302823 NM_005214.4 182 aCa/aTa 0 +CTNNA3 UCSF GRCh37 10 69281603 69281603 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 76 20 146 0 ENST00000433211.2:c.576G>A p.Gln192= p.Q192= ENST00000433211 NM_013266.2 192 caG/caA 0 +CTSL2 UCSF GRCh37 9 99799878 99799878 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 266 62 339 0 ENST00000259470.5:c.146G>A p.Arg49Lys p.R49K ENST00000259470 NM_001333.3 49 aGa/aAa 0 +CTTNBP2NL UCSF GRCh37 1 112991731 112991731 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 81 22 91 0 ENST00000271277.6:c.267G>A p.Gln89= p.Q89= ENST00000271277 NM_018704.2 89 caG/caA 0 +CTU2 UCSF GRCh37 16 88776418 88776418 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 122 31 274 0 ENST00000453996.2:c.216C>T p.Gly72= p.G72= ENST00000453996 NM_001012759.1 72 ggC/ggT 0 +CUL7 UCSF GRCh37 6 43005665 43005665 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 90 15 72 0 ENST00000535468.1:c.5110G>A p.Asp1704Asn p.D1704N ENST00000535468 NM_014780.4 1704 Gac/Aac 0 +CX3CL1 UCSF GRCh37 16 57416257 57416257 + synonymous_variant Silent SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 56 29 102 0 ENST00000006053.6:c.507C>A p.Leu169= p.L169= ENST00000006053 NM_002996.3 169 ctC/ctA 0 +CYB5D1 UCSF GRCh37 17 7762789 7762789 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 121 39 199 0 ENST00000332439.4:c.546G>A p.Gly182= p.G182= ENST00000332439 NM_144607.4 182 ggG/ggA 0 +CYFIP2 UCSF GRCh37 5 156747704 156747704 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 58 37 169 0 ENST00000521420.1:c.1487G>A p.Gly496Glu p.G496E ENST00000521420 496 gGa/gAa 0 +CYP26C1 UCSF GRCh37 10 94828367 94828367 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 17 10 37 0 ENST00000285949.5:c.1482G>A p.Thr494= p.T494= ENST00000285949 NM_183374.2 494 acG/acA 0 +CYTH2 UCSF GRCh37 19 48973630 48973630 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 157 53 231 0 ENST00000452733.2:c.40G>A p.Glu14Lys p.E14K ENST00000452733 14 Gag/Aag 0 +DACT1 UCSF GRCh37 14 59107525 59107525 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 152 56 243 0 ENST00000335867.4:c.417G>A p.Leu139= p.L139= ENST00000335867 139 ctG/ctA 0 +DBF4B UCSF GRCh37 17 42828469 42828469 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 167 59 280 0 ENST00000315005.3:c.1696C>T p.Pro566Ser p.P566S ENST00000315005 NM_145663.2 566 Ccc/Tcc 0 +DCHS1 UCSF GRCh37 11 6648774 6648774 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 8 117 0 ENST00000299441.3:c.5496G>A p.Gln1832= p.Q1832= ENST00000299441 NM_003737.2 1832 caG/caA 0 +DCHS1 UCSF GRCh37 11 6643673 6643673 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 11 46 0 ENST00000299441.3:c.9234C>T p.Asp3078= p.D3078= ENST00000299441 NM_003737.2 3078 gaC/gaT 0 +DDR1 UCSF GRCh37 6 30865957 30865957 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 204 27 145 0 ENST00000376575.3:c.2342G>A p.Gly781Glu p.G781E ENST00000376575 781 gGg/gAg 0 +DDX18 UCSF GRCh37 2 118586528 118586528 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 46 8 57 0 ENST00000263239.2:c.1639C>T p.Pro547Ser p.P547S ENST00000263239 NM_006773.3 547 Cca/Tca 0 +DDX49 UCSF GRCh37 19 19033453 19033453 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 29 141 0 ENST00000247003.4:c.676G>A p.Val226Met p.V226M ENST00000247003 NM_019070.4 226 Gtg/Atg 0 +DENND2D UCSF GRCh37 1 111740573 111740573 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 40 18 48 0 ENST00000357640.4:c.395G>A p.Ser132Asn p.S132N ENST00000357640 NM_024901.4 132 aGc/aAc 0 +DIDO1 UCSF GRCh37 20 61511428 61511428 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 209 52 314 0 ENST00000266070.4:c.5880G>A p.Arg1960= p.R1960= ENST00000266070 NM_033081.2 1960 agG/agA 0 +DLEC1 UCSF GRCh37 3 38125727 38125727 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 129 35 150 1 ENST00000308059.6:c.1252C>T p.Leu418= p.L418= ENST00000308059 418 Ctg/Ttg 0 +DLGAP4 UCSF GRCh37 20 35125306 35125306 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 22 155 0 ENST00000373913.3:c.1847C>T p.Thr616Ile p.T616I ENST00000373913 616 aCc/aTc 0 +DLL4 UCSF GRCh37 15 41229048 41229048 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 137 42 171 0 ENST00000249749.5:c.1863C>T p.Pro621= p.P621= ENST00000249749 NM_019074.3 621 ccC/ccT 0 +DMXL1 UCSF GRCh37 5 118469874 118469874 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 168 27 188 0 ENST00000311085.8:c.2254+1G>A p.X752_splice ENST00000311085 NM_005509.4 0 +DNAH11 UCSF GRCh37 7 21723468 21723468 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 253 109 475 1 ENST00000328843.6:c.5548C>T p.His1850Tyr p.H1850Y ENST00000328843 1850 Cac/Tac 0 +DNAH9 UCSF GRCh37 17 11583146 11583146 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 154 46 251 1 ENST00000262442.4:c.3426C>T p.Phe1142= p.F1142= ENST00000262442 NM_001372.3 1142 ttC/ttT 0 +DNAH9 UCSF GRCh37 17 11795177 11795177 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 187 39 242 1 ENST00000262442.4:c.11196C>T p.Asp3732= p.D3732= ENST00000262442 NM_001372.3 3732 gaC/gaT 0 +DNAJC13 UCSF GRCh37 3 132203503 132203503 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 133 26 142 0 ENST00000260818.6:c.3254C>T p.Pro1085Leu p.P1085L ENST00000260818 NM_015268.3 1085 cCc/cTc 0 +DNAJC13 UCSF GRCh37 3 132172971 132172971 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 86 12 85 0 ENST00000260818.6:c.902G>A p.Gly301Glu p.G301E ENST00000260818 NM_015268.3 301 gGg/gAg 0 +DNAJC14 UCSF GRCh37 12 56221696 56221696 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 103 46 214 0 ENST00000357606.3:c.747G>A p.Gln249= p.Q249= ENST00000357606 249 caG/caA 0 +DNPEP UCSF GRCh37 2 220251054 220251054 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 50 246 0 ENST00000273075.4:c.413C>T p.Thr138Ile p.T138I ENST00000273075 NM_012100.2 138 aCc/aTc 0 +DOCK5 UCSF GRCh37 8 25174587 25174587 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 345 42 467 1 ENST00000276440.7:c.1383G>A p.Lys461= p.K461= ENST00000276440 NM_024940.6 461 aaG/aaA 0 +DPCD UCSF GRCh37 10 103361091 103361091 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 95 40 221 0 ENST00000370151.4:c.402G>A p.Lys134= p.K134= ENST00000370151 NM_015448.1 134 aaG/aaA 0 +DPEP2 UCSF GRCh37 16 68026929 68026929 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 11 6 31 0 ENST00000412757.2:c.187A>G p.Thr63Ala p.T63A ENST00000412757 63 Aca/Gca 0 +DPP8 UCSF GRCh37 15 65756199 65756199 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 72 16 89 0 ENST00000341861.5:c.1919G>A p.Ser640Asn p.S640N ENST00000341861 NM_197960.2 640 aGt/aAt 0 +DPP8 UCSF GRCh37 15 65771336 65771336 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 64 24 63 0 ENST00000341861.5:c.1386G>A p.Glu462= p.E462= ENST00000341861 NM_197960.2 462 gaG/gaA 0 +DPP9 UCSF GRCh37 19 4697580 4697580 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 37 31 85 0 ENST00000262960.9:c.1158G>A p.Trp386Ter p.W386* ENST00000262960 NM_139159.4 386 tgG/tgA 0 +DPYSL5 UCSF GRCh37 2 27165609 27165609 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 69 24 126 0 ENST00000288699.6:c.1431G>A p.Gln477= p.Q477= ENST00000288699 NM_001253724.1 477 caG/caA 0 +DSCAM UCSF GRCh37 21 41668075 41668075 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 133 27 138 0 ENST00000400454.1:c.2089C>T p.Arg697Trp p.R697W ENST00000400454 NM_001271534.1 697 Cgg/Tgg 0 +DST UCSF GRCh37 6 56483139 56483139 + intron_variant Intron SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 164 24 119 0 ENST00000244364.6:c.3319-3857G>A *1107* ENST00000244364 NM_015548.4 0 +DST UCSF GRCh37 6 56438626 56438626 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 333 39 281 0 ENST00000244364.6:c.5218C>T p.Leu1740Phe p.L1740F ENST00000244364 NM_015548.4 1740 Ctc/Ttc 0 +DTNA UCSF GRCh37 18 32462088 32462088 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 20 137 0 ENST00000598334.1:c.1957G>A p.Asp653Asn p.D653N ENST00000598334 NM_001198938.1 653 Gac/Aac 0 +DUOX2 UCSF GRCh37 15 45386450 45386450 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 84 25 103 0 ENST00000603300.1:c.4545C>T p.Phe1515= p.F1515= ENST00000603300 NM_014080.4 1515 ttC/ttT 0 +DYTN UCSF GRCh37 2 207569614 207569614 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 51 250 0 ENST00000452335.2:c.436C>T p.Arg146Cys p.R146C ENST00000452335 NM_001093730.1 146 Cgc/Tgc 0 +EBF4 UCSF GRCh37 20 2690257 2690257 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 18 3 34 0 ENST00000380648.4:c.514G>A p.Glu172Lys p.E172K ENST00000380648 NM_001110514.1 172 Gag/Aag 0 +EDC4 UCSF GRCh37 16 67915601 67915601 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 25 135 0 ENST00000358933.5:c.2857C>T p.Leu953= p.L953= ENST00000358933 NM_014329.4 953 Cta/Tta 0 +EEF1A1 UCSF GRCh37 6 74228138 74228138 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 52 33 288 0 ENST00000316292.9:c.968G>A p.Gly323Asp p.G323D ENST00000316292 NM_001402.5 323 gGc/gAc 0 +EFR3A UCSF GRCh37 8 132966207 132966207 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 150 29 126 0 ENST00000254624.5:c.631G>A p.Val211Ile p.V211I ENST00000254624 NM_015137.4 211 Gtt/Att 0 +EHD1 UCSF GRCh37 11 64645795 64645795 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 147 48 248 0 ENST00000320631.3:c.142C>T p.Pro48Ser p.P48S ENST00000320631 NM_006795.2 48 Ccc/Tcc 0 +EHMT2 UCSF GRCh37 6 31864468 31864468 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 199 29 135 0 ENST00000375537.4:c.243C>T p.Thr81= p.T81= ENST00000375537 NM_006709.3 81 acC/acT 0 +EIF2AK2 UCSF GRCh37 2 37374877 37374877 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 155 51 268 0 ENST00000233057.4:c.73C>T p.Leu25Phe p.L25F ENST00000233057 NM_001135651.2 25 Ctt/Ttt 0 +EIF2AK3 UCSF GRCh37 2 88874467 88874467 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 188 45 273 0 ENST00000303236.3:c.2534G>A p.Ser845Asn p.S845N ENST00000303236 NM_004836.5 845 aGc/aAc 0 +EIF2C1 UCSF GRCh37 1 36360759 36360759 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 135 23 199 0 ENST00000373204.4:c.909G>A p.Glu303= p.E303= ENST00000373204 NM_012199.2 303 gaG/gaA 0 +EIF2D UCSF GRCh37 1 206772907 206772907 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 141 28 179 0 ENST00000271764.2:c.1112G>A p.Ser371Asn p.S371N ENST00000271764 NM_006893.2 371 aGc/aAc 0 +ELANE UCSF GRCh37 19 855770 855770 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 31 100 0 ENST00000590230.1:c.573G>A p.Arg191= p.R191= ENST00000590230 191 agG/agA 0 +ELL UCSF GRCh37 19 18572590 18572590 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 127 20 142 0 ENST00000262809.4:c.542C>T p.Pro181Leu p.P181L ENST00000262809 NM_006532.3 181 cCc/cTc 0 +ELMO3 UCSF GRCh37 16 67236151 67236151 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 168 56 291 0 ENST00000393997.2:c.1384G>A p.Val462Met p.V462M ENST00000393997 NM_024712.3 462 Gtg/Atg 0 +EME1 UCSF GRCh37 17 48456458 48456458 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 118 30 151 1 ENST00000393271.2:c.1142C>T p.Pro381Leu p.P381L ENST00000393271 NM_001166131.1 381 cCc/cTc 0 +EMR1 UCSF GRCh37 19 6937382 6937382 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 102 43 194 1 ENST00000312053.4:c.2510G>A p.Gly837Glu p.G837E ENST00000312053 NM_001974.4 837 gGg/gAg 0 +ENTHD1 UCSF GRCh37 22 40140178 40140178 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 112 28 132 0 ENST00000325157.6:c.1330C>T p.Pro444Ser p.P444S ENST00000325157 NM_152512.3 444 Cct/Tct 0 +EP400 UCSF GRCh37 12 132529870 132529870 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 54 16 98 0 ENST00000389561.2:c.6791G>A p.Gly2264Asp p.G2264D ENST00000389561 NM_015409.4 2264 gGc/gAc 0 +EPB41L4B UCSF GRCh37 9 111947801 111947801 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 55 11 72 0 ENST00000374566.3:c.2386G>A p.Val796Ile p.V796I ENST00000374566 NM_019114.3 796 Gtt/Att 0 +EPC2 UCSF GRCh37 2 149447906 149447906 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 282 59 375 0 ENST00000258484.6:c.277G>A p.Glu93Lys p.E93K ENST00000258484 NM_015630.3 93 Gag/Aag 0 +EPHA6 UCSF GRCh37 3 97198182 97198182 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 63 10 96 0 ENST00000389672.5:c.2048G>A p.Arg683Lys p.R683K ENST00000389672 NM_001080448.2 683 aGa/aAa 0 +EPHB3 UCSF GRCh37 3 184293762 184293762 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 51 222 0 ENST00000330394.2:c.1001G>A p.Ser334Asn p.S334N ENST00000330394 NM_004443.3 334 aGt/aAt 0 +EPRS UCSF GRCh37 1 220160503 220160503 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 108 30 130 0 ENST00000366923.3:c.3019G>A p.Gly1007Arg p.G1007R ENST00000366923 NM_004446.2 1007 Ggg/Agg 0 +ERCC6L UCSF GRCh37 X 71427075 71427075 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 80 44 126 0 ENST00000334463.3:c.1542G>A p.Leu514= p.L514= ENST00000334463 NM_017669.2 514 ttG/ttA 0 +ERCC8 UCSF GRCh37 5 60240799 60240799 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 153 22 171 0 ENST00000265038.5:c.37G>A p.Glu13Lys p.E13K ENST00000265038 NM_000082.3 13 Gag/Aag 0 +ESPL1 UCSF GRCh37 12 53663436 53663436 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 209 88 413 0 ENST00000257934.4:c.710G>A p.Gly237Glu p.G237E ENST00000257934 NM_012291.4 237 gGg/gAg 0 +ESRP1 UCSF GRCh37 8 95654212 95654212 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 217 43 206 0 ENST00000433389.2:c.161G>A p.Arg54Lys p.R54K ENST00000433389 NM_001034915.2 54 aGa/aAa 0 +EVC2 UCSF GRCh37 4 5624425 5624425 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 48 37 99 0 ENST00000344408.5:c.2340C>T p.His780= p.H780= ENST00000344408 NM_147127.4 780 caC/caT 0 +EYA3 UCSF GRCh37 1 28384522 28384522 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 139 36 163 0 ENST00000373871.3:c.16G>A p.Asp6Asn p.D6N ENST00000373871 6 Gat/Aat 0 +FAAH UCSF GRCh37 1 46871454 46871454 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 61 23 105 0 ENST00000243167.8:c.773G>A p.Gly258Glu p.G258E ENST00000243167 NM_001441.2 258 gGg/gAg 0 +FAF2 UCSF GRCh37 5 175906208 175906208 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 25 133 0 ENST00000261942.6:c.83C>T p.Ser28Phe p.S28F ENST00000261942 NM_014613.2 28 tCt/tTt 0 +FAM109B UCSF GRCh37 22 42474031 42474031 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 16 7 15 0 ENST00000321753.3:c.734G>A p.Arg245Lys p.R245K ENST00000321753 NM_001002034.2 245 aGg/aAg 0 +FAM110B UCSF GRCh37 8 59059817 59059817 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 81 17 131 0 ENST00000361488.3:c.1028C>T p.Ser343Phe p.S343F ENST00000361488 NM_147189.2 343 tCt/tTt 0 +FAM117B UCSF GRCh37 2 203622117 203622117 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 77 14 138 0 ENST00000392238.2:c.1286G>A p.Ser429Asn p.S429N ENST00000392238 429 aGt/aAt 0 +FAM120A UCSF GRCh37 9 96320950 96320950 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 112 36 144 0 ENST00000277165.6:c.2756G>A p.Cys919Tyr p.C919Y ENST00000277165 NM_014612.3 919 tGc/tAc 0 +FAM120AOS UCSF GRCh37 9 96214878 96214878 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 36 13 54 0 ENST00000375412.5:c.114C>T p.Asp38= p.D38= ENST00000375412 NM_198841.2 38 gaC/gaT 0 +FAM153A UCSF GRCh37 5 177166124 177166124 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 60 9 136 1 ENST00000440605.3:c.321C>T p.Thr107= p.T107= ENST00000440605 NM_173663.3 107 acC/acT 0 +FAM179B UCSF GRCh37 14 45432574 45432574 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 33 148 0 ENST00000361577.3:c.950G>A p.Ser317Asn p.S317N ENST00000361577 NM_015091.2 317 aGt/aAt 0 +FAM184B UCSF GRCh37 4 17636702 17636702 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 110 29 129 0 ENST00000265018.3:c.2819G>A p.Ser940Asn p.S940N ENST00000265018 NM_015688.1 940 aGt/aAt 0 +FAM208B UCSF GRCh37 10 5789811 5789811 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 151 22 146 0 ENST00000328090.5:c.4427C>T p.Ser1476Phe p.S1476F ENST00000328090 NM_017782.4 1476 tCt/tTt 0 +FAM21B UCSF GRCh37 10 47911067 47911067 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 28 5 73 0 ENST00000358474.5:c.935C>T p.Pro312Leu p.P312L ENST00000358474 NM_018232.1 312 cCt/cTt 0 +FAM40A UCSF GRCh37 1 110582130 110582130 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 12 6 37 0 ENST00000369795.3:c.574G>A p.Glu192Lys p.E192K ENST00000369795 NM_033088.3 192 Gaa/Aaa 0 +FAM40B UCSF GRCh37 7 129096376 129096376 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 86 33 189 0 ENST00000249344.2:c.931G>A p.Val311Met p.V311M ENST00000249344 NM_020704.2 311 Gtg/Atg 0 +FAM47C UCSF GRCh37 X 37026847 37026847 + stop_gained Nonsense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 82 56 152 0 ENST00000358047.3:c.364G>T p.Glu122Ter p.E122* ENST00000358047 NM_001013736.2 122 Gaa/Taa 0 +FAM76A UCSF GRCh37 1 28081740 28081740 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 178 48 232 0 ENST00000010299.6:c.736A>G p.Thr246Ala p.T246A ENST00000010299 246 Act/Gct 0 +FAM96A UCSF GRCh37 15 64365200 64365200 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 136 50 144 0 ENST00000300030.3:c.413G>A p.Arg138Gln p.R138Q ENST00000300030 NM_032231.4 138 cGa/cAa 0 +FAN1 UCSF GRCh37 15 31221558 31221558 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 173 38 222 0 ENST00000362065.4:c.2745C>T p.Ser915= p.S915= ENST00000362065 NM_014967.4 915 tcC/tcT 0 +FANCM UCSF GRCh37 14 45668044 45668044 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 86 34 122 0 ENST00000267430.5:c.5914G>A p.Ala1972Thr p.A1972T ENST00000267430 NM_020937.2 1972 Gca/Aca 0 +FAT1 UCSF GRCh37 4 187557930 187557930 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 332 173 707 1 ENST00000441802.2:c.3781G>A p.Asp1261Asn p.D1261N ENST00000441802 NM_005245.3 1261 Gac/Aac 0 +FBXL18 UCSF GRCh37 7 5530973 5530973 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 24 8 39 0 ENST00000382368.3:c.1889C>T p.Pro630Leu p.P630L ENST00000382368 NM_024963.4 630 cCc/cTc 0 +FBXO5 UCSF GRCh37 6 153296649 153296649 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 85 45 181 0 ENST00000229758.3:c.211C>T p.Leu71= p.L71= ENST00000229758 NM_012177.3 71 Cta/Tta 0 +FCGR2A UCSF GRCh37 1 161483691 161483691 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 249 57 355 1 ENST00000271450.6:c.749C>T p.Ser250Phe p.S250F ENST00000271450 NM_021642.3 250 tCc/tTc 0 +FCGR3B UCSF GRCh37 1 161600921 161600921 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 157 43 259 0 ENST00000531221.1:c.72G>A p.Arg24= p.R24= ENST00000531221 24 cgG/cgA 0 +FEM1C UCSF GRCh37 5 114879155 114879155 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 111 35 130 0 ENST00000274457.3:c.36G>A p.Arg12= p.R12= ENST00000274457 NM_020177.2 12 cgG/cgA 0 +FERMT3 UCSF GRCh37 11 63978216 63978216 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 266 60 368 0 ENST00000279227.5:c.294G>A p.Arg98= p.R98= ENST00000279227 NM_178443.2 98 cgG/cgA 0 +FGFR2 UCSF GRCh37 10 123278254 123278254 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 37 24 143 0 ENST00000358487.5:c.939+1239C>T *313* ENST00000358487 NM_000141.4 0 +FILIP1L UCSF GRCh37 3 99643078 99643078 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 239 71 349 0 ENST00000354552.3:c.601G>A p.Glu201Lys p.E201K ENST00000354552 NM_182909.2 201 Gaa/Aaa 0 +FIP1L1 UCSF GRCh37 4 54319248 54319249 + frameshift_variant Frame_Shift_Del DEL AG AG - 1000g2010nov_all P21_Rec Untested WXS Illumina HiSeq 20 0 ENST00000337488.6:c.1459_1460delAG p.Arg487GlyfsTer3 p.R487Gfs*3 ENST00000337488 NM_030917.3 483 AGa/a 0 +FKBP10 UCSF GRCh37 17 39974720 39974720 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 57 19 96 0 ENST00000321562.4:c.668C>T p.Pro223Leu p.P223L ENST00000321562 NM_021939.3 223 cCt/cTt 0 +FLG UCSF GRCh37 1 152280250 152280250 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 545 153 995 0 ENST00000368799.1:c.7112G>A p.Ser2371Asn p.S2371N ENST00000368799 NM_002016.1 2371 aGt/aAt 0 +FLG UCSF GRCh37 1 152287016 152287016 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 175 31 196 0 ENST00000368799.1:c.346G>A p.Glu116Lys p.E116K ENST00000368799 NM_002016.1 116 Gaa/Aaa 0 +FLNB UCSF GRCh37 3 58064451 58064451 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 27 3 29 0 ENST00000490882.1:c.549C>T p.Cys183= p.C183= ENST00000490882 NM_001164317.1 183 tgC/tgT 0 +FLT1 UCSF GRCh37 13 29012374 29012374 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 30 5 86 0 ENST00000282397.4:c.497C>T p.Thr166Ile p.T166I ENST00000282397 NM_002019.4 166 aCt/aTt 0 +FMN2 UCSF GRCh37 1 240370916 240370916 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 60 27 118 1 ENST00000319653.9:c.2804C>T p.Pro935Leu p.P935L ENST00000319653 NM_020066.4 935 cCc/cTc 0 +FMO1 UCSF GRCh37 1 171254589 171254589 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 164 39 167 0 ENST00000354841.4:c.1505G>A p.Arg502Gln p.R502Q ENST00000354841 NM_001282692.1 502 cGa/cAa 0 +FOXJ3 UCSF GRCh37 1 42657376 42657376 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 184 24 286 0 ENST00000372572.1:c.949C>T p.Pro317Ser p.P317S ENST00000372572 NM_001198851.1 317 Cct/Tct 0 +FPGT UCSF GRCh37 1 74671005 74671005 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 44 175 0 ENST00000609362.1:c.1274G>A p.Gly425Glu p.G425E ENST00000609362 425 gGg/gAg 0 +FRAS1 UCSF GRCh37 4 79430074 79430074 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 71 44 216 0 ENST00000264895.6:c.9694G>A p.Val3232Met p.V3232M ENST00000264895 NM_025074.6 3232 Gtg/Atg 0 +FSIP2 UCSF GRCh37 2 186670828 186670828 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 115 32 204 0 ENST00000343098.5:c.17062G>C p.Val5688Leu p.V5688L ENST00000343098 NM_173651.2 5688 Gta/Cta 0 +FTSJD1 UCSF GRCh37 16 71318473 71318473 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 105 31 118 0 ENST00000338099.5:c.1351G>A p.Glu451Lys p.E451K ENST00000338099 451 Gaa/Aaa 0 +FYTTD1 UCSF GRCh37 3 197482706 197482706 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 108 23 221 0 ENST00000241502.4:c.104-591G>A *35* ENST00000241502 NM_032288.6 0 +GABRA4 UCSF GRCh37 4 46979087 46979087 + missense_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 30 4 46 0 ENST00000264318.3:c.568T>A p.Phe190Ile p.F190I ENST00000264318 NM_000809.3 190 Ttc/Atc 0 +GABRG3 UCSF GRCh37 15 27765224 27765224 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 35 147 0 ENST00000333743.6:c.819G>A p.Val273= p.V273= ENST00000333743 NM_033223.4 273 gtG/gtA 0 +GADD45B UCSF GRCh37 19 2477114 2477114 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 69 15 95 0 ENST00000215631.4:c.234C>T p.Ile78= p.I78= ENST00000215631 NM_015675.3 78 atC/atT 0 +GALNT8 UCSF GRCh37 12 4853683 4853683 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 22 107 0 ENST00000252318.2:c.677G>A p.Gly226Glu p.G226E ENST00000252318 NM_017417.1 226 gGa/gAa 0 +GALNTL1 UCSF GRCh37 14 69799836 69799836 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 51 18 105 0 ENST00000337827.4:c.813G>A p.Gln271= p.Q271= ENST00000337827 NM_020692.2 271 caG/caA 0 +GATA2 UCSF GRCh37 3 128204813 128204813 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 45 9 76 0 ENST00000341105.2:c.628G>A p.Gly210Ser p.G210S ENST00000341105 NM_032638.4 210 Ggc/Agc 0 +GBA UCSF GRCh37 1 155204985 155204985 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 186 56 305 0 ENST00000327247.5:c.1505+1G>A p.X502_splice ENST00000327247 NM_001005742.2 0 +GBGT1 UCSF GRCh37 9 136030687 136030687 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 44 9 67 0 ENST00000372040.3:c.237G>A p.Leu79= p.L79= ENST00000372040 79 ctG/ctA 0 +GGA1 UCSF GRCh37 22 38019349 38019349 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 262 67 371 0 ENST00000343632.4:c.625G>A p.Glu209Lys p.E209K ENST00000343632 NM_013365.4 209 Gag/Aag 0 +GHRHR UCSF GRCh37 7 31008546 31008546 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 69 21 117 0 ENST00000326139.2:c.155C>T p.Thr52Ile p.T52I ENST00000326139 NM_000823.3 52 aCc/aTc 0 +GIPC3 UCSF GRCh37 19 3586840 3586840 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 57 14 99 0 ENST00000322315.5:c.440G>A p.Arg147Gln p.R147Q ENST00000322315 NM_133261.2 147 cGg/cAg 0 +GJA4 UCSF GRCh37 1 35260362 35260362 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 18 170 0 ENST00000342280.4:c.548C>T p.Pro183Leu p.P183L ENST00000342280 NM_002060.2 183 cCc/cTc 0 +GLG1 UCSF GRCh37 16 74542750 74542750 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 66 9 86 0 ENST00000205061.5:c.545C>T p.Ser182Phe p.S182F ENST00000205061 NM_012201.5 182 tCt/tTt 0 +GLI3 UCSF GRCh37 7 42005317 42005317 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 198 24 316 0 ENST00000395925.3:c.3354C>T p.Asp1118= p.D1118= ENST00000395925 NM_000168.5 1118 gaC/gaT 0 +GLIPR1 UCSF GRCh37 12 75874799 75874799 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 38 154 0 ENST00000266659.3:c.139G>A p.Glu47Lys p.E47K ENST00000266659 NM_006851.2 47 Gag/Aag 0 +GMCL1 UCSF GRCh37 2 70096865 70096865 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 24 134 0 ENST00000282570.3:c.1233G>A p.Trp411Ter p.W411* ENST00000282570 NM_178439.3 411 tgG/tgA 0 +GMIP UCSF GRCh37 19 19745726 19745726 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 165 74 182 0 ENST00000203556.4:c.1762G>A p.Val588Ile p.V588I ENST00000203556 NM_016573.2 588 Gtc/Atc 0 +GMIP UCSF GRCh37 19 19740773 19740773 + stop_retained_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 23 4 24 0 ENST00000203556.4:c.2912G>A p.Ter971= p.*971= ENST00000203556 NM_016573.2 971 tGa/tAa 0 +GNAI2 UCSF GRCh37 3 50290583 50290583 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 192 24 289 0 ENST00000313601.6:c.431C>T p.Ser144Leu p.S144L ENST00000313601 NM_002070.2 144 tCa/tTa 0 +GNL3L UCSF GRCh37 X 54569664 54569664 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 24 5 53 0 ENST00000336470.4:c.415C>T p.Leu139= p.L139= ENST00000336470 NM_019067.5 139 Ctg/Ttg 0 +GPC1 UCSF GRCh37 2 241401873 241401873 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 43 9 43 0 ENST00000264039.2:c.591G>A p.Glu197= p.E197= ENST00000264039 NM_002081.2 197 gaG/gaA 0 +GPER UCSF GRCh37 7 1131933 1131933 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 83 40 169 0 ENST00000397092.1:c.569T>C p.Leu190Pro p.L190P ENST00000397092 NM_001039966.1 190 cTg/cCg 0 +GPLD1 UCSF GRCh37 6 24475433 24475433 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 138 18 154 0 ENST00000230036.1:c.357G>A p.Leu119= p.L119= ENST00000230036 NM_001503.3 119 ttG/ttA 0 +GPR111 UCSF GRCh37 6 47649587 47649587 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 437 53 322 0 ENST00000296862.1:c.1292C>T p.Ser431Phe p.S431F ENST00000296862 431 tCt/tTt 0 +GPR112 UCSF GRCh37 X 135432388 135432388 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 66 57 130 0 ENST00000394143.1:c.6523C>T p.Leu2175= p.L2175= ENST00000394143 NM_153834.3 2175 Ctg/Ttg 0 +GPR114 UCSF GRCh37 16 57600590 57600590 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 37 214 0 ENST00000340339.4:c.626G>A p.Cys209Tyr p.C209Y ENST00000340339 NM_153837.1 209 tGt/tAt 0 +GPR125 UCSF GRCh37 4 22390463 22390463 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 141 24 138 0 ENST00000334304.5:c.2831G>A p.Arg944Lys p.R944K ENST00000334304 NM_145290.3 944 aGa/aAa 0 +GPR125 UCSF GRCh37 4 22389518 22389518 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 159 34 171 0 ENST00000334304.5:c.3776C>T p.Thr1259Ile p.T1259I ENST00000334304 NM_145290.3 1259 aCc/aTc 0 +GPR15 UCSF GRCh37 3 98251207 98251207 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 116 34 174 0 ENST00000284311.3:c.330C>T p.Ser110= p.S110= ENST00000284311 NM_005290.2 110 tcC/tcT 0 +GPR155 UCSF GRCh37 2 175335141 175335141 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 55 17 101 0 ENST00000392552.2:c.1003C>T p.Gln335Ter p.Q335* ENST00000392552 NM_152529.6 335 Caa/Taa 0 +GRIN3A UCSF GRCh37 9 104432882 104432882 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 114 30 167 0 ENST00000361820.3:c.1812G>A p.Lys604= p.K604= ENST00000361820 NM_133445.2 604 aaG/aaA 0 +GSTA5 UCSF GRCh37 6 52701042 52701042 + synonymous_variant Silent SNP C C T snp132_rs61735553 P21_Rec Untested WXS Illumina HiSeq 503 67 463 0 ENST00000370989.2:c.264G>A p.Glu88= p.E88= ENST00000370989 88 gaG/gaA 0 +GTF2F1 UCSF GRCh37 19 6380431 6380431 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 326 83 504 1 ENST00000394456.5:c.1415A>G p.Asp472Gly p.D472G ENST00000394456 NM_002096.2 472 gAc/gGc 0 +GTPBP2 UCSF GRCh37 6 43596768 43596768 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 9 28 0 ENST00000307126.5:c.132G>A p.Lys44= p.K44= ENST00000307126 NM_019096.3 44 aaG/aaA 0 +GTPBP4 UCSF GRCh37 10 1054927 1054927 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 116 42 180 0 ENST00000360803.4:c.1143G>A p.Val381= p.V381= ENST00000360803 NM_012341.2 381 gtG/gtA 0 +GULP1 UCSF GRCh37 2 189405948 189405948 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 71 37 124 0 ENST00000409580.1:c.302G>A p.Cys101Tyr p.C101Y ENST00000409580 101 tGt/tAt 0 +GZF1 UCSF GRCh37 20 23351007 23351007 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 148 27 202 0 ENST00000338121.5:c.2065G>A p.Glu689Lys p.E689K ENST00000338121 689 Gag/Aag 0 +GZF1 UCSF GRCh37 20 23346133 23346133 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 167 58 341 0 ENST00000338121.5:c.1113C>T p.His371= p.H371= ENST00000338121 371 caC/caT 0 +H2AFY UCSF GRCh37 5 134670722 134670722 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 148 48 206 0 ENST00000511689.1:c.1063G>A p.Asp355Asn p.D355N ENST00000511689 NM_138610.2 355 Gac/Aac 0 +HAUS1 UCSF GRCh37 18 43702472 43702472 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 90 24 140 0 ENST00000282058.6:c.516G>A p.Arg172= p.R172= ENST00000282058 NM_138443.3 172 agG/agA 0 +HAUS5 UCSF GRCh37 19 36113550 36113550 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 83 17 80 0 ENST00000203166.5:c.1699C>T p.Leu567= p.L567= ENST00000203166 NM_015302.1 567 Ctg/Ttg 0 +HAUS8 UCSF GRCh37 19 17160698 17160698 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 231 59 331 0 ENST00000253669.5:c.1218G>A p.Gly406= p.G406= ENST00000253669 406 ggG/ggA 0 +HEATR1 UCSF GRCh37 1 236722401 236722401 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 91 20 112 0 ENST00000366582.3:c.4805C>T p.Pro1602Leu p.P1602L ENST00000366582 NM_018072.5 1602 cCt/cTt 0 +HEATR5A UCSF GRCh37 14 31813262 31813262 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 37 169 0 ENST00000389961.3:c.3050C>T p.Thr1017Ile p.T1017I ENST00000389961 1017 aCt/aTt 0 +HEATR5B UCSF GRCh37 2 37302778 37302778 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 105 33 177 0 ENST00000233099.5:c.448-1G>A p.X150_splice ENST00000233099 NM_019024.1 0 +HECW2 UCSF GRCh37 2 197184437 197184437 + stop_gained Nonsense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 95 44 197 0 ENST00000260983.3:c.1177G>T p.Glu393Ter p.E393* ENST00000260983 NM_020760.1 393 Gaa/Taa 0 +HERC1 UCSF GRCh37 15 63964892 63964892 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 130 23 144 1 ENST00000443617.2:c.7848G>A p.Glu2616= p.E2616= ENST00000443617 NM_003922.3 2616 gaG/gaA 0 +HERC2 UCSF GRCh37 15 28408402 28408402 + synonymous_variant Silent SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 115 17 165 0 ENST00000261609.7:c.10584T>C p.Gly3528= p.G3528= ENST00000261609 NM_004667.5 3528 ggT/ggC 0 +HERC3 UCSF GRCh37 4 89583686 89583686 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 47 39 111 0 ENST00000402738.1:c.1251C>T p.His417= p.H417= ENST00000402738 NM_014606.2 417 caC/caT 0 +HGS UCSF GRCh37 17 79663016 79663016 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 59 18 101 0 ENST00000329138.4:c.1380G>A p.Leu460= p.L460= ENST00000329138 NM_004712.4 460 ctG/ctA 0 +HHIPL2 UCSF GRCh37 1 222721267 222721267 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 46 24 83 0 ENST00000343410.6:c.120G>A p.Gln40= p.Q40= ENST00000343410 NM_024746.3 40 caG/caA 0 +HIBADH UCSF GRCh37 7 27582634 27582634 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 47 22 83 0 ENST00000265395.2:c.570G>A p.Gly190= p.G190= ENST00000265395 NM_152740.3 190 ggG/ggA 0 +HINFP UCSF GRCh37 11 119001584 119001584 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 104 57 318 0 ENST00000350777.2:c.331C>T p.Pro111Ser p.P111S ENST00000350777 NM_198971.2 111 Ccc/Tcc 0 +HIPK1 UCSF GRCh37 1 114516014 114516014 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 243 66 329 0 ENST00000369558.1:c.3513C>T p.Ala1171= p.A1171= ENST00000369558 1171 gcC/gcT 0 +HIST1H2AH UCSF GRCh37 6 27115070 27115070 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 235 193 280 0 ENST00000377459.1:c.163G>C p.Val55Leu p.V55L ENST00000377459 NM_080596.2 55 Gtg/Ctg 0 +HK3 UCSF GRCh37 5 176314586 176314586 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 26 12 88 0 ENST00000292432.5:c.1466C>T p.Pro489Leu p.P489L ENST00000292432 NM_002115.2 489 cCa/cTa 0 +HLA-DQA2 UCSF GRCh37 6 32713057 32713057 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 499 67 352 0 ENST00000374940.3:c.204C>T p.Val68= p.V68= ENST00000374940 NM_020056.4 68 gtC/gtT 0 +HMOX2 UCSF GRCh37 16 4556969 4556969 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 339 50 568 0 ENST00000570646.1:c.160G>A p.Val54Ile p.V54I ENST00000570646 NM_002134.3 54 Gtc/Atc 0 +HNRNPH1 UCSF GRCh37 5 179046349 179046349 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 129 74 331 0 ENST00000356731.5:c.457G>A p.Gly153Arg p.G153R ENST00000356731 153 Ggg/Agg 0 +HOXB2 UCSF GRCh37 17 46620758 46620758 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 34 16 30 0 ENST00000330070.4:c.743C>T p.Pro248Leu p.P248L ENST00000330070 NM_002145.3 248 cCg/cTg 0 +HP1BP3 UCSF GRCh37 1 21106840 21106840 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 59 9 55 0 ENST00000312239.5:c.94G>A p.Glu32Lys p.E32K ENST00000312239 NM_016287.3 32 Gag/Aag 0 +HRNR UCSF GRCh37 1 152193713 152193713 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 285 65 301 0 ENST00000368801.2:c.392G>A p.Ser131Asn p.S131N ENST00000368801 NM_001009931.2 131 aGt/aAt 0 +HSP90AB1 UCSF GRCh37 6 44216400 44216400 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 546 86 320 0 ENST00000371554.1:c.34G>A p.Val12Met p.V12M ENST00000371554 12 Gtg/Atg 0 +HSPA4 UCSF GRCh37 5 132426984 132426984 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 191 47 246 1 ENST00000304858.2:c.1478C>A p.Ser493Tyr p.S493Y ENST00000304858 NM_002154.3 493 tCc/tAc 0 +HSPG2 UCSF GRCh37 1 22206919 22206919 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 55 13 103 0 ENST00000374695.3:c.2132C>T p.Ala711Val p.A711V ENST00000374695 NM_005529.5 711 gCc/gTc 0 +HTR7 UCSF GRCh37 10 92508880 92508880 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 36 200 1 ENST00000336152.3:c.1011C>T p.Thr337= p.T337= ENST00000336152 NM_019859.3 337 acC/acT 0 +HUWE1 UCSF GRCh37 X 53579645 53579645 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 57 28 91 0 ENST00000342160.3:c.8704G>A p.Gly2902Ser p.G2902S ENST00000342160 2902 Ggc/Agc 0 +IARS2 UCSF GRCh37 1 220273858 220273858 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 84 16 74 0 ENST00000302637.5:c.417C>T p.Phe139= p.F139= ENST00000302637 NM_018060.3 139 ttC/ttT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 30 74 126 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IDO1 UCSF GRCh37 8 39776390 39776390 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 381 65 450 0 ENST00000518237.1:c.360G>A p.Leu120= p.L120= ENST00000518237 NM_002164.5 120 ctG/ctA 0 +IFITM1 UCSF GRCh37 11 314927 314927 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 48 18 172 0 ENST00000408968.3:c.192G>A p.Arg64= p.R64= ENST00000408968 NM_003641.3 64 agG/agA 0 +IFT172 UCSF GRCh37 2 27668177 27668177 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 4 34 0 ENST00000260570.3:c.5054C>T p.Pro1685Leu p.P1685L ENST00000260570 NM_015662.1 1685 cCc/cTc 0 +IFT172 UCSF GRCh37 2 27704119 27704119 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 39 21 65 0 ENST00000260570.3:c.579G>A p.Leu193= p.L193= ENST00000260570 NM_015662.1 193 ttG/ttA 0 +IGSF10 UCSF GRCh37 3 151166450 151166450 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 189 50 258 0 ENST00000282466.3:c.1319G>A p.Arg440Lys p.R440K ENST00000282466 NM_178822.4 440 aGa/aAa 0 +IGSF22 UCSF GRCh37 11 18730979 18730979 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 49 230 0 ENST00000513874.1:c.2953G>A p.Glu985Lys p.E985K ENST00000513874 NM_173588.3 985 Gag/Aag 0 +IGSF9 UCSF GRCh37 1 159900927 159900927 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 70 23 95 1 ENST00000368094.1:c.1637+1G>A p.X546_splice ENST00000368094 NM_001135050.1 0 +IKBKAP UCSF GRCh37 9 111679912 111679912 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 207 41 185 0 ENST00000374647.5:c.779C>T p.Pro260Leu p.P260L ENST00000374647 NM_003640.3 260 cCc/cTc 0 +IKBKAP UCSF GRCh37 9 111692117 111692117 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 242 28 295 1 ENST00000374647.5:c.235G>A p.Asp79Asn p.D79N ENST00000374647 NM_003640.3 79 Gat/Aat 0 +IL10RB UCSF GRCh37 21 34648906 34648906 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 365 55 295 1 ENST00000290200.2:c.179G>A p.Arg60Lys p.R60K ENST00000290200 NM_000628.4 60 aGg/aAg 0 +INA UCSF GRCh37 10 105037185 105037185 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 16 73 0 ENST00000369849.4:c.217G>A p.Asp73Asn p.D73N ENST00000369849 NM_032727.3 73 Gac/Aac 0 +INA UCSF GRCh37 10 105037961 105037961 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 12 6 33 0 ENST00000369849.4:c.993G>A p.Gly331= p.G331= ENST00000369849 NM_032727.3 331 ggG/ggA 0 +INCENP UCSF GRCh37 11 61917663 61917663 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 32 184 0 ENST00000394818.3:c.2526C>T p.Ile842= p.I842= ENST00000394818 NM_001040694.1 842 atC/atT 0 +INF2 UCSF GRCh37 14 105169465 105169465 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 34 193 0 ENST00000392634.4:c.415G>A p.Val139Met p.V139M ENST00000392634 NM_022489.3 139 Gtg/Atg 0 +INO80 UCSF GRCh37 15 41289801 41289801 + splice_acceptor_variant Splice_Site SNP T T A NOVEL P21_Rec Untested WXS Illumina HiSeq 65 17 86 1 ENST00000361937.3:c.3498-2A>T p.X1166_splice ENST00000361937 0 +INO80 UCSF GRCh37 15 41313228 41313228 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 94 30 135 0 ENST00000361937.3:c.3144G>A p.Gln1048= p.Q1048= ENST00000361937 1048 caG/caA 0 +INPPL1 UCSF GRCh37 11 71948227 71948227 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 104 96 223 0 ENST00000298229.2:c.2939G>C p.Ser980Thr p.S980T ENST00000298229 NM_001567.3 980 aGc/aCc 0 +INSR UCSF GRCh37 19 7141710 7141710 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 110 22 148 0 ENST00000302850.5:c.2660G>A p.Ser887Asn p.S887N ENST00000302850 NM_000208.2 887 aGt/aAt 0 +INSRR UCSF GRCh37 1 156828357 156828357 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 109 23 137 0 ENST00000368195.3:c.57C>T p.Ser19= p.S19= ENST00000368195 NM_014215.2 19 tcC/tcT 0 +INTS10 UCSF GRCh37 8 19703277 19703277 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 21 80 0 ENST00000397977.3:c.1945G>A p.Glu649Lys p.E649K ENST00000397977 NM_018142.2 649 Gaa/Aaa 0 +INVS UCSF GRCh37 9 103054908 103054908 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 95 31 125 0 ENST00000262457.2:c.2369C>T p.Pro790Leu p.P790L ENST00000262457 NM_014425.3 790 cCc/cTc 0 +IQGAP3 UCSF GRCh37 1 156504354 156504354 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 58 10 72 0 ENST00000361170.2:c.3679G>A p.Gly1227Arg p.G1227R ENST00000361170 NM_178229.4 1227 Ggg/Agg 0 +IRAK4 UCSF GRCh37 12 44165049 44165049 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 65 27 86 0 ENST00000448290.2:c.188G>A p.Gly63Glu p.G63E ENST00000448290 NM_016123.3 63 gGa/gAa 0 +IRF2BP2 UCSF GRCh37 1 234743379 234743379 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 147 38 212 0 ENST00000366609.3:c.1268C>T p.Ser423Phe p.S423F ENST00000366609 NM_182972.2 423 tCc/tTc 0 +IRF2BPL UCSF GRCh37 14 77491854 77491854 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 96 45 169 0 ENST00000238647.3:c.2282G>A p.Gly761Glu p.G761E ENST00000238647 NM_024496.3 761 gGa/gAa 0 +IRF2BPL UCSF GRCh37 14 77492290 77492290 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 17 5 21 0 ENST00000238647.3:c.1846G>A p.Ala616Thr p.A616T ENST00000238647 NM_024496.3 616 Gcc/Acc 0 +ITGB1 UCSF GRCh37 10 33211251 33211251 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 195 58 176 0 ENST00000396033.2:c.1062G>A p.Lys354= p.K354= ENST00000396033 NM_133376.2 354 aaG/aaA 0 +ITGB2 UCSF GRCh37 21 46306818 46306818 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 14 112 0 ENST00000397850.2:c.2081-1G>A p.X694_splice ENST00000397850 0 +ITIH4 UCSF GRCh37 3 52848224 52848224 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 16 77 0 ENST00000266041.4:c.2626+1G>A p.X876_splice ENST00000266041 NM_002218.4 0 +ITIH5 UCSF GRCh37 10 7618900 7618900 + synonymous_variant Silent SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 111 58 137 0 ENST00000256861.6:c.1494C>A p.Ala498= p.A498= ENST00000256861 NM_030569.6 498 gcC/gcA 0 +JAKMIP2 UCSF GRCh37 5 147020296 147020296 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 93 49 233 0 ENST00000265272.5:c.1372C>T p.Pro458Ser p.P458S ENST00000265272 NM_014790.4 458 Cca/Tca 0 +JAM2 UCSF GRCh37 21 27071072 27071072 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 145 24 130 0 ENST00000400532.1:c.478G>A p.Gly160Arg p.G160R ENST00000400532 NM_001270408.1 160 Ggg/Agg 0 +JARID2 UCSF GRCh37 6 15496685 15496685 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 156 22 147 0 ENST00000341776.2:c.1229G>A p.Ser410Asn p.S410N ENST00000341776 NM_004973.3 410 aGt/aAt 0 +KAT6B UCSF GRCh37 10 76737107 76737107 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 22 140 0 ENST00000287239.4:c.2027G>A p.Ser676Asn p.S676N ENST00000287239 NM_001256468.1 676 aGt/aAt 0 +KCNH7 UCSF GRCh37 2 163302755 163302755 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 93 25 200 0 ENST00000332142.5:c.1327G>A p.Glu443Lys p.E443K ENST00000332142 NM_033272.3 443 Gaa/Aaa 0 +KCNJ14 UCSF GRCh37 19 48967778 48967778 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 30 147 0 ENST00000391884.1:c.1055C>T p.Thr352Ile p.T352I ENST00000391884 352 aCt/aTt 0 +KCNJ3 UCSF GRCh37 2 155711377 155711377 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 128 31 197 0 ENST00000295101.2:c.1058C>T p.Thr353Ile p.T353I ENST00000295101 NM_002239.3 353 aCc/aTc 0 +KCNMA1 UCSF GRCh37 10 78870030 78870030 + synonymous_variant Silent SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 194 82 334 0 ENST00000404857.1:c.1032T>C p.Tyr344= p.Y344= ENST00000404857 NM_001161353.1 344 taT/taC 0 +KCNQ5 UCSF GRCh37 6 73332281 73332281 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 16 7 44 0 ENST00000342056.2:c.364C>T p.Pro122Ser p.P122S ENST00000342056 NM_001160132.1 122 Ccc/Tcc 0 +KCTD15 UCSF GRCh37 19 34302256 34302256 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 14 60 0 ENST00000430256.3:c.492G>A p.Arg164= p.R164= ENST00000430256 164 cgG/cgA 0 +KDM4D UCSF GRCh37 11 94731128 94731128 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 115 59 318 0 ENST00000335080.5:c.592C>T p.Leu198Phe p.L198F ENST00000335080 NM_018039.2 198 Ctt/Ttt 0 +KDM5C UCSF GRCh37 X 53225875 53225875 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 36 27 78 0 ENST00000375401.3:c.2974G>A p.Glu992Lys p.E992K ENST00000375401 NM_004187.3 992 Gag/Aag 0 +KDM5D UCSF GRCh37 Y 21877842 21877842 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 46 106 0 ENST00000317961.4:c.2080G>A p.Glu694Lys p.E694K ENST00000317961 NM_004653.4 694 Gaa/Aaa 0 +KDM5D UCSF GRCh37 Y 21868399 21868399 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 13 11 45 0 ENST00000317961.4:c.4197G>A p.Glu1399= p.E1399= ENST00000317961 NM_004653.4 1399 gaG/gaA 0 +KIAA0020 UCSF GRCh37 9 2837245 2837245 + missense_variant Missense_Mutation SNP T T A NOVEL P21_Rec Untested WXS Illumina HiSeq 71 245 542 0 ENST00000397885.2:c.239A>T p.Asn80Ile p.N80I ENST00000397885 NM_014878.4 80 aAc/aTc 0 +KIAA0319L UCSF GRCh37 1 35944779 35944779 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 26 125 0 ENST00000325722.3:c.701C>T p.Thr234Ile p.T234I ENST00000325722 NM_024874.4 234 aCc/aTc 0 +KIAA0753 UCSF GRCh37 17 6531854 6531854 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 53 210 0 ENST00000361413.3:c.301G>A p.Val101Ile p.V101I ENST00000361413 NM_014804.2 101 Gtc/Atc 0 +KIAA0825 UCSF GRCh37 5 93775796 93775796 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 182 29 233 0 ENST00000312498.7:c.2388G>A p.Glu796= p.E796= ENST00000312498 796 gaG/gaA 0 +KIAA0889 UCSF GRCh37 20 35421664 35421664 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 15 82 0 ENST00000237536.4:c.4821C>T p.Val1607= p.V1607= ENST00000237536 NM_080627.2 1607 gtC/gtT 0 +KIAA1191 UCSF GRCh37 5 175774703 175774703 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 102 14 215 0 ENST00000298569.4:c.818C>T p.Pro273Leu p.P273L ENST00000298569 NM_020444.3 273 cCc/cTc 0 +KIAA1199 UCSF GRCh37 15 81201554 81201554 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 93 18 139 0 ENST00000394685.3:c.1704G>A p.Arg568= p.R568= ENST00000394685 568 agG/agA 0 +KIAA1211 UCSF GRCh37 4 57181573 57181573 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 70 8 64 0 ENST00000504228.1:c.1905G>A p.Gly635= p.G635= ENST00000504228 635 ggG/ggA 0 +KIAA1486 UCSF GRCh37 2 226378195 226378195 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 197 82 368 0 ENST00000272907.6:c.330C>T p.Cys110= p.C110= ENST00000272907 NM_020864.1 110 tgC/tgT 0 +KIAA1704 UCSF GRCh37 13 45589195 45589195 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 26 8 90 0 ENST00000361121.2:c.517G>A p.Glu173Lys p.E173K ENST00000361121 173 Gaa/Aaa 0 +KIAA2018 UCSF GRCh37 3 113376584 113376584 + synonymous_variant Silent SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 234 77 296 0 ENST00000316407.4:c.3945A>G p.Pro1315= p.P1315= ENST00000316407 NM_001009899.2 1315 ccA/ccG 0 +KIF13A UCSF GRCh37 6 17817420 17817422 + frameshift_variant Frame_Shift_Del DEL CTA CTA TT NOVEL P21_Rec Untested WXS Illumina HiSeq 30 0 ENST00000259711.6:c.1829_1831delinsAA p.Leu610GlnfsTer8 p.L610Qfs*8 ENST00000259711 NM_022113.5 610 cTAGaa/cAAaa 0 +KIF17 UCSF GRCh37 1 20991147 20991147 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 71 9 98 0 ENST00000247986.2:c.3020C>T p.Ser1007Phe p.S1007F ENST00000247986 1007 tCc/tTc 0 +KIF1B UCSF GRCh37 1 10363361 10363361 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 120 21 132 0 ENST00000263934.6:c.1977+6057G>A *659* ENST00000263934 NM_015074.3 0 +KIF20B UCSF GRCh37 10 91483742 91483742 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 56 11 112 0 ENST00000260753.4:c.1744G>A p.Asp582Asn p.D582N ENST00000260753 NM_016195.2 582 Gac/Aac 0 +KIF23 UCSF GRCh37 15 69737233 69737233 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 43 210 0 ENST00000260363.4:c.2484G>A p.Met828Ile p.M828I ENST00000260363 NM_138555.3 828 atG/atA 0 +KIF23 UCSF GRCh37 15 69738636 69738636 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 100 21 96 0 ENST00000260363.4:c.2729G>A p.Arg910Lys p.R910K ENST00000260363 NM_138555.3 910 aGa/aAa 0 +KIF6 UCSF GRCh37 6 39563952 39563952 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 89 98 0 ENST00000287152.7:c.724C>T p.Arg242Ter p.R242* ENST00000287152 NM_145027.4 242 Cga/Tga 0 +KIFC1 UCSF GRCh37 6 33372666 33372666 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 153 20 120 0 ENST00000428849.2:c.794G>A p.Ser265Asn p.S265N ENST00000428849 NM_002263.3 265 aGc/aAc 0 +KL UCSF GRCh37 13 33591228 33591228 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 27 3 46 0 ENST00000380099.3:c.650G>A p.Arg217Lys p.R217K ENST00000380099 NM_004795.3 217 aGg/aAg 0 +KLHDC7B UCSF GRCh37 22 50988351 50988351 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 24 4 39 0 ENST00000395676.2:c.1756C>T p.Pro586Ser p.P586S ENST00000395676 NM_138433.3 586 Cct/Tct 0 +KLHL20 UCSF GRCh37 1 173702880 173702880 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 146 29 190 0 ENST00000209884.4:c.52G>A p.Gly18Arg p.G18R ENST00000209884 NM_014458.3 18 Gga/Aga 0 +KLK3 UCSF GRCh37 19 51362853 51362853 + intron_variant Intron SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 104 25 159 0 ENST00000326003.2:c.631-375C>T *211* ENST00000326003 NM_001030047.1 0 +KLRC2 UCSF GRCh37 12 10586474 10586474 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 185 68 163 1 ENST00000381902.2:c.399G>A p.Lys133= p.K133= ENST00000381902 NM_002260.3 133 aaG/aaA 0 +KMO UCSF GRCh37 1 241755331 241755331 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 183 37 233 0 ENST00000366559.4:c.1337C>T p.Ser446Leu p.S446L ENST00000366559 NM_003679.4 446 tCa/tTa 0 +KPNA2 UCSF GRCh37 17 66040553 66040553 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 398 115 528 0 ENST00000537025.2:c.1281C>T p.Asn427= p.N427= ENST00000537025 427 aaC/aaT 0 +KPNB1 UCSF GRCh37 17 45755738 45755738 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 122 17 140 0 ENST00000290158.4:c.2312G>A p.Gly771Glu p.G771E ENST00000290158 NM_002265.5 771 gGa/gAa 0 +KRT9 UCSF GRCh37 17 39728026 39728026 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 19 12 38 0 ENST00000246662.4:c.219C>T p.Tyr73= p.Y73= ENST00000246662 NM_000226.3 73 taC/taT 0 +KRTAP4-1 UCSF GRCh37 17 39341039 39341039 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 93 37 160 0 ENST00000398472.1:c.68C>A p.Thr23Asn p.T23N ENST00000398472 23 aCc/aAc 0 +KSR1 UCSF GRCh37 17 25909824 25909824 + missense_variant Missense_Mutation SNP C C T snp132_rs34914492 P21_Rec Untested WXS Illumina HiSeq 44 14 77 0 ENST00000398988.3:c.262C>T p.Pro88Ser p.P88S ENST00000398988 NM_014238.1 88 Cca/Tca 0 +LAMA1 UCSF GRCh37 18 7023359 7023359 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 70 19 110 0 ENST00000389658.3:c.2505C>T p.Tyr835= p.Y835= ENST00000389658 NM_005559.3 835 taC/taT 0 +LAMA3 UCSF GRCh37 18 21494764 21494764 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 8 51 0 ENST00000313654.9:c.7584C>T p.Leu2528= p.L2528= ENST00000313654 NM_198129.1 2528 ctC/ctT 0 +LAMB4 UCSF GRCh37 7 107671346 107671346 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 163 32 228 0 ENST00000388781.3:c.4897C>T p.Leu1633= p.L1633= ENST00000388781 NM_007356.2 1633 Ctg/Ttg 0 +LETM1 UCSF GRCh37 4 1823925 1823925 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 99 11 119 0 ENST00000302787.2:c.1591G>A p.Val531Met p.V531M ENST00000302787 NM_012318.2 531 Gtg/Atg 0 +LETM1 UCSF GRCh37 4 1827392 1827392 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 61 20 74 0 ENST00000302787.2:c.1099G>A p.Val367Met p.V367M ENST00000302787 NM_012318.2 367 Gtg/Atg 0 +LGALS14 UCSF GRCh37 19 40197953 40197953 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 366 97 482 1 ENST00000360675.3:c.315G>A p.Glu105= p.E105= ENST00000360675 NM_203471.1 105 gaG/gaA 0 +LIX1L UCSF GRCh37 1 145487444 145487444 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 118 25 131 0 ENST00000369308.3:c.433G>A p.Gly145Arg p.G145R ENST00000369308 NM_153713.2 145 Gga/Aga 0 +LMOD2 UCSF GRCh37 7 123303046 123303046 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 36 16 65 0 ENST00000458573.2:c.1406C>T p.Ala469Val p.A469V ENST00000458573 NM_207163.1 469 gCc/gTc 0 +LOXL3 UCSF GRCh37 2 74779470 74779470 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 34 9 82 0 ENST00000264094.3:c.292G>A p.Ala98Thr p.A98T ENST00000264094 NM_032603.2 98 Gcc/Acc 0 +LPA UCSF GRCh37 6 160952788 160952788 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 65 40 221 0 ENST00000447678.1:c.6096G>A p.Trp2032Ter p.W2032* ENST00000447678 NM_005577.2 2032 tgG/tgA 0 +LPA UCSF GRCh37 6 161056204 161056204 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 487 62 972 0 ENST00000447678.1:c.1026G>A p.Ala342= p.A342= ENST00000447678 NM_005577.2 342 gcG/gcA 0 +LPAR3 UCSF GRCh37 1 85331417 85331417 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 456 91 694 0 ENST00000440886.1:c.387G>A p.Met129Ile p.M129I ENST00000440886 129 atG/atA 0 +LPHN3 UCSF GRCh37 4 62453029 62453029 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 59 235 0 ENST00000514591.1:c.140G>A p.Gly47Glu p.G47E ENST00000514591 47 gGa/gAa 0 +LRMP UCSF GRCh37 12 25232607 25232607 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 152 35 119 0 ENST00000354454.3:c.154C>T p.Leu52= p.L52= ENST00000354454 NM_006152.3 52 Ctg/Ttg 0 +LRRC19 UCSF GRCh37 9 26995558 26995558 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 39 8 46 0 ENST00000380055.5:c.1074C>T p.Asp358= p.D358= ENST00000380055 NM_022901.2 358 gaC/gaT 0 +LRRC8C UCSF GRCh37 1 90179564 90179564 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 139 41 212 0 ENST00000370454.4:c.1435G>A p.Val479Ile p.V479I ENST00000370454 NM_032270.4 479 Gtc/Atc 0 +LRRC8C UCSF GRCh37 1 90180190 90180190 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 118 34 121 0 ENST00000370454.4:c.2061C>T p.Tyr687= p.Y687= ENST00000370454 NM_032270.4 687 taC/taT 0 +LRRIQ1 UCSF GRCh37 12 85432020 85432020 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 76 21 126 0 ENST00000393217.2:c.66C>T p.Ser22= p.S22= ENST00000393217 NM_001079910.1 22 tcC/tcT 0 +LRRK2 UCSF GRCh37 12 40758823 40758823 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 143 27 136 0 ENST00000298910.7:c.7361C>T p.Ser2454Leu p.S2454L ENST00000298910 NM_198578.3 2454 tCg/tTg 0 +LRRTM2 UCSF GRCh37 5 138209046 138209046 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 163 93 440 0 ENST00000274711.6:c.1204G>A p.Gly402Ser p.G402S ENST00000274711 NM_015564.2 402 Ggc/Agc 0 +LTBP2 UCSF GRCh37 14 75078270 75078270 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.006,1000g2011may_all_0.0052 P21_Rec Untested WXS Illumina HiSeq 32 6 40 0 ENST00000261978.4:c.378C>T p.Pro126= p.P126= ENST00000261978 NM_000428.2 126 ccC/ccT 0 +LTN1 UCSF GRCh37 21 30329684 30329684 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 150 28 114 0 ENST00000389194.2:c.3000G>T p.Trp1000Cys p.W1000C ENST00000389194 NM_015565.2 1000 tgG/tgT 0 +M6PR UCSF GRCh37 12 9098119 9098119 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 169 36 199 0 ENST00000000412.3:c.238G>A p.Glu80Lys p.E80K ENST00000000412 NM_002355.3 80 Gaa/Aaa 0 +MACF1 UCSF GRCh37 1 39753082 39753082 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 334 60 462 0 ENST00000545844.1:c.1648G>A p.Ala550Thr p.A550T ENST00000545844 550 Gca/Aca 0 +MAGI2 UCSF GRCh37 7 78636498 78636498 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 20 132 0 ENST00000354212.4:c.326G>A p.Arg109His p.R109H ENST00000354212 NM_012301.3 109 cGt/cAt 0 +MAN2A1 UCSF GRCh37 5 109200736 109200736 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 25 110 0 ENST00000261483.4:c.3172-1G>A p.X1058_splice ENST00000261483 NM_002372.2 0 +MAP2 UCSF GRCh37 2 210560059 210560059 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 352 66 306 0 ENST00000360351.4:c.3165G>A p.Gln1055= p.Q1055= ENST00000360351 NM_002374.3 1055 caG/caA 0 +MAP3K1 UCSF GRCh37 5 56177036 56177036 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 87 17 85 0 ENST00000399503.3:c.2306C>T p.Pro769Leu p.P769L ENST00000399503 NM_005921.1 769 cCt/cTt 0 +MAP3K14 UCSF GRCh37 17 43344879 43344879 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 58 15 69 0 ENST00000344686.2:n.2326G>A *776* ENST00000344686 0 +MAP3K6 UCSF GRCh37 1 27683593 27683593 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 35 8 55 0 ENST00000493901.1:c.3271C>T p.Leu1091Phe p.L1091F ENST00000493901 NM_004672.3 1091 Ctc/Ttc 0 +MAP4K2 UCSF GRCh37 11 64557083 64557083 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 25 8 47 0 ENST00000294066.2:c.2389G>A p.Glu797Lys p.E797K ENST00000294066 NM_004579.3 797 Gag/Aag 0 +MAP4K4 UCSF GRCh37 2 102488148 102488148 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 90 30 173 0 ENST00000347699.4:c.2517+1271G>A *839* ENST00000347699 NM_145687.3 0 +MAP6 UCSF GRCh37 11 75299168 75299168 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 173 46 231 0 ENST00000304771.3:c.1378G>A p.Asp460Asn p.D460N ENST00000304771 NM_033063.1 460 Gac/Aac 0 +MAP7D1 UCSF GRCh37 1 36644187 36644187 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 13 4 19 0 ENST00000373151.2:c.1876G>A p.Glu626Lys p.E626K ENST00000373151 NM_018067.3 626 Gaa/Aaa 0 +MAP7D1 UCSF GRCh37 1 36638150 36638150 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 8 45 0 ENST00000373151.2:c.546G>A p.Leu182= p.L182= ENST00000373151 NM_018067.3 182 ctG/ctA 0 +MAPK13 UCSF GRCh37 6 36106555 36106555 + missense_variant,splice_region_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 91 14 73 0 ENST00000211287.4:c.839A>T p.Gln280Leu p.Q280L ENST00000211287 NM_002754.4 280 cAg/cTg 0 +MAPKAPK5 UCSF GRCh37 12 112321443 112321443 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 210 73 407 0 ENST00000551404.2:c.719C>T p.Pro240Leu p.P240L ENST00000551404 240 cCt/cTt 0 +MBTPS1 UCSF GRCh37 16 84089694 84089694 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 30 175 0 ENST00000343411.3:c.2878G>A p.Val960Met p.V960M ENST00000343411 NM_003791.2 960 Gtg/Atg 0 +MCC UCSF GRCh37 5 112478934 112478934 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 75 17 80 0 ENST00000408903.3:c.865C>T p.Leu289= p.L289= ENST00000408903 NM_001085377.1 289 Ctg/Ttg 0 +MCM3AP UCSF GRCh37 21 47695166 47695166 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 45 14 55 0 ENST00000397708.1:c.1932G>A p.Lys644= p.K644= ENST00000397708 644 aaG/aaA 0 +MCM4 UCSF GRCh37 8 48885522 48885522 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 12 81 0 ENST00000262105.2:c.2034G>A p.Glu678= p.E678= ENST00000262105 NM_005914.3 678 gaG/gaA 0 +MCM6 UCSF GRCh37 2 136610432 136610432 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 24 112 0 ENST00000264156.2:c.1680G>A p.Glu560= p.E560= ENST00000264156 NM_005915.5 560 gaG/gaA 0 +MECOM UCSF GRCh37 3 169099279 169099279 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 112 91 176 1 ENST00000486748.1:c.143T>C p.Ile48Thr p.I48T ENST00000486748 48 aTa/aCa 0 +MED12 UCSF GRCh37 X 70341647 70341647 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 53 28 73 0 ENST00000374080.3:c.1082G>A p.Gly361Asp p.G361D ENST00000374080 361 gGc/gAc 0 +MED12 UCSF GRCh37 X 70347192 70347192 + synonymous_variant Silent SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 37 24 48 0 ENST00000374080.3:c.2856T>C p.Cys952= p.C952= ENST00000374080 952 tgT/tgC 0 +MFAP1 UCSF GRCh37 15 44109561 44109561 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 190 47 212 0 ENST00000267812.3:c.165G>A p.Glu55= p.E55= ENST00000267812 NM_005926.2 55 gaG/gaA 0 +MFHAS1 UCSF GRCh37 8 8748927 8748927 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 102 47 150 0 ENST00000276282.6:c.1642G>A p.Glu548Lys p.E548K ENST00000276282 NM_004225.2 548 Gag/Aag 0 +MFHAS1 UCSF GRCh37 8 8749257 8749257 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 86 27 151 0 ENST00000276282.6:c.1312C>T p.Pro438Ser p.P438S ENST00000276282 NM_004225.2 438 Cca/Tca 0 +MFSD8 UCSF GRCh37 4 128861044 128861044 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 34 39 127 0 ENST00000296468.3:c.662G>A p.Gly221Glu p.G221E ENST00000296468 NM_152778.2 221 gGa/gAa 0 +MICAL3 UCSF GRCh37 22 18347444 18347444 + intron_variant Intron SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 3 36 0 ENST00000441493.2:c.2605+221C>T *869* ENST00000441493 NM_015241.2 0 +MIER1 UCSF GRCh37 1 67411859 67411859 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 153 37 162 0 ENST00000401041.1:c.220G>A p.Glu74Lys p.E74K ENST00000401041 NM_001077700.2 74 Gaa/Aaa 0 +MIOS UCSF GRCh37 7 7646697 7646697 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 58 9 122 1 ENST00000340080.4:c.2602G>A p.Val868Ile p.V868I ENST00000340080 NM_019005.3 868 Gta/Ata 0 +MKI67 UCSF GRCh37 10 129902612 129902612 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 72 386 0 ENST00000368654.3:c.7492G>A p.Val2498Ile p.V2498I ENST00000368654 NM_002417.4 2498 Gtc/Atc 0 +MKRN2 UCSF GRCh37 3 12623345 12623345 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 284 76 310 0 ENST00000170447.7:c.1007C>T p.Thr336Ile p.T336I ENST00000170447 NM_014160.4 336 aCc/aTc 0 +MLF2 UCSF GRCh37 12 6861100 6861100 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 157 26 183 0 ENST00000203630.5:c.171G>A p.Arg57= p.R57= ENST00000203630 57 cgG/cgA 0 +MLL UCSF GRCh37 11 118373420 118373420 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 101 23 259 1 ENST00000534358.1:c.6813G>A p.Arg2271= p.R2271= ENST00000534358 NM_005933.3 2271 agG/agA 0 +MLL2 UCSF GRCh37 12 49443842 49443842 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 85 32 128 0 ENST00000301067.7:c.3529G>A p.Gly1177Arg p.G1177R ENST00000301067 NM_003482.3 1177 Ggg/Agg 0 +MLL3 UCSF GRCh37 7 152027799 152027799 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 37 178 0 ENST00000262189.6:c.276G>A p.Glu92= p.E92= ENST00000262189 NM_170606.2 92 gaG/gaA 0 +MMS19 UCSF GRCh37 10 99236698 99236698 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 150 61 336 0 ENST00000438925.2:c.516C>T p.Asp172= p.D172= ENST00000438925 NM_022362.4 172 gaC/gaT 0 +MOV10L1 UCSF GRCh37 22 50572463 50572463 + synonymous_variant Silent SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 42 8 42 0 ENST00000262794.5:c.1938A>G p.Ala646= p.A646= ENST00000262794 NM_018995.2 646 gcA/gcG 0 +MRPL39 UCSF GRCh37 21 26973701 26973701 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 89 15 84 0 ENST00000307301.7:c.499G>A p.Val167Ile p.V167I ENST00000307301 NM_080794.3 167 Gtc/Atc 0 +MRPL48 UCSF GRCh37 11 73556001 73556001 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 183 56 210 0 ENST00000310614.7:c.351C>T p.Leu117= p.L117= ENST00000310614 NM_016055.5 117 ctC/ctT 0 +MRPS18B UCSF GRCh37 6 30593516 30593516 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 234 44 198 0 ENST00000259873.4:c.719C>T p.Pro240Leu p.P240L ENST00000259873 NM_014046.3 240 cCt/cTt 0 +MRPS7 UCSF GRCh37 17 73257992 73257992 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 20 3 22 0 ENST00000245539.6:c.11C>T p.Pro4Leu p.P4L ENST00000245539 NM_015971.3 4 cCc/cTc 0 +MTERFD1 UCSF GRCh37 8 97256170 97256170 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 173 32 133 0 ENST00000287025.3:c.1036C>T p.His346Tyr p.H346Y ENST00000287025 NM_015942.3 346 Cac/Tac 0 +MTHFR UCSF GRCh37 1 11862938 11862938 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 71 20 160 0 ENST00000376592.1:c.236G>A p.Arg79Lys p.R79K ENST00000376592 79 aGg/aAg 0 +MTMR10 UCSF GRCh37 15 31253149 31253149 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 235 48 264 0 ENST00000435680.1:c.693C>T p.Ile231= p.I231= ENST00000435680 NM_017762.2 231 atC/atT 0 +MUC16 UCSF GRCh37 19 9071859 9071859 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 445 115 601 1 ENST00000397910.4:c.15587G>A p.Ser5196Asn p.S5196N ENST00000397910 NM_024690.2 5196 aGt/aAt 0 +MUC5B UCSF GRCh37 11 1264731 1264731 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 86 38 219 0 ENST00000529681.1:c.6621C>T p.Pro2207= p.P2207= ENST00000529681 NM_002458.2 2207 ccC/ccT 0 +MX1 UCSF GRCh37 21 42817417 42817417 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 215 46 199 0 ENST00000398600.2:c.1051C>G p.Gln351Glu p.Q351E ENST00000398600 NM_001144925.1 351 Cag/Gag 0 +MYCBP2 UCSF GRCh37 13 77844511 77844511 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 38 28 109 0 ENST00000544440.2:c.994C>T p.Gln332Ter p.Q332* ENST00000544440 332 Cag/Tag 0 +MYCBP2 UCSF GRCh37 13 77635322 77635322 + stop_gained Nonsense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 39 19 99 0 ENST00000544440.2:c.12904G>T p.Glu4302Ter p.E4302* ENST00000544440 4302 Gaa/Taa 0 +MYH1 UCSF GRCh37 17 10402076 10402076 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 153 55 255 0 ENST00000226207.5:c.4048C>T p.Gln1350Ter p.Q1350* ENST00000226207 NM_005963.3 1350 Cag/Tag 0 +MYH6 UCSF GRCh37 14 23873582 23873582 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 142 63 267 0 ENST00000405093.3:c.658C>T p.Gln220Ter p.Q220* ENST00000405093 NM_002471.3 220 Cag/Tag 0 +MYH9 UCSF GRCh37 22 36681211 36681211 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 120 30 201 0 ENST00000216181.5:c.5439G>A p.Glu1813= p.E1813= ENST00000216181 NM_002473.4 1813 gaG/gaA 0 +MYLK UCSF GRCh37 3 123333125 123333125 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 191 71 283 0 ENST00000360304.3:c.5572G>C p.Asp1858His p.D1858H ENST00000360304 NM_053025.3 1858 Gac/Cac 0 +MYO1C UCSF GRCh37 17 1384175 1384175 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 61 22 107 0 ENST00000359786.5:c.632C>T p.Ala211Val p.A211V ENST00000359786 NM_001080779.1 211 gCc/gTc 0 +MYO1G UCSF GRCh37 7 45005692 45005692 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 41 9 78 0 ENST00000258787.7:c.2137A>G p.Ile713Val p.I713V ENST00000258787 NM_033054.2 713 Att/Gtt 0 +MYO7B UCSF GRCh37 2 128378042 128378042 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 26 15 63 0 ENST00000428314.1:c.3447+1G>A p.X1149_splice ENST00000428314 NM_001080527.1 0 +MZT2A UCSF GRCh37 2 132241665 132241665 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 101 36 196 0 ENST00000309451.6:c.446C>T p.Pro149Leu p.P149L ENST00000309451 NM_001085365.1 149 cCt/cTt 0 +N4BP2 UCSF GRCh37 4 40144355 40144355 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 78 23 144 0 ENST00000261435.6:c.4848C>T p.Tyr1616= p.Y1616= ENST00000261435 NM_018177.4 1616 taC/taT 0 +NALCN UCSF GRCh37 13 101725987 101725987 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 42 15 111 0 ENST00000251127.6:c.4146G>A p.Leu1382= p.L1382= ENST00000251127 NM_052867.2 1382 ctG/ctA 0 +NAT8L UCSF GRCh37 4 2062856 2062856 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 29 9 38 0 ENST00000423729.2:c.508G>A p.Ala170Thr p.A170T ENST00000423729 NM_178557.3 170 Gcg/Acg 0 +NBPF10 UCSF GRCh37 1 145327548 145327548 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 23 7 17 0 ENST00000342960.5:c.4105A>G p.Asn1369Asp p.N1369D ENST00000342960 NM_001039703.5 1369 Aat/Gat 0 +NCBP1 UCSF GRCh37 9 100410414 100410414 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 89 15 123 1 ENST00000375147.3:c.806C>T p.Pro269Leu p.P269L ENST00000375147 NM_002486.4 269 cCt/cTt 0 +NCOA4 UCSF GRCh37 10 51585212 51585212 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 180 70 372 0 ENST00000452682.1:c.1359G>A p.Lys453= p.K453= ENST00000452682 NM_001145260.1 453 aaG/aaA 0 +NCOR2 UCSF GRCh37 12 124885083 124885083 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 101 47 212 0 ENST00000405201.1:c.1777G>A p.Glu593Lys p.E593K ENST00000405201 593 Gag/Aag 0 +NES UCSF GRCh37 1 156641450 156641450 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 138 40 138 0 ENST00000368223.3:c.2530G>A p.Glu844Lys p.E844K ENST00000368223 NM_006617.1 844 Gaa/Aaa 0 +NET1 UCSF GRCh37 10 5494478 5494478 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 17 88 0 ENST00000355029.4:c.521G>A p.Arg174Lys p.R174K ENST00000355029 NM_001047160.2 174 aGa/aAa 0 +NFASC UCSF GRCh37 1 204948528 204948528 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 244 60 345 0 ENST00000339876.6:c.2017G>A p.Gly673Arg p.G673R ENST00000339876 NM_001005388.2 673 Ggg/Agg 0 +NFATC3 UCSF GRCh37 16 68160380 68160380 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 128 43 182 0 ENST00000346183.3:c.1268C>T p.Pro423Leu p.P423L ENST00000346183 NM_173165.2 423 cCt/cTt 0 +NFIX UCSF GRCh37 19 13184830 13184830 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 158 38 220 0 ENST00000397661.2:c.808C>T p.Pro270Ser p.P270S ENST00000397661 NM_002501.2 270 Cct/Tct 0 +NHSL1 UCSF GRCh37 6 138745224 138745224 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 20 8 54 0 ENST00000427025.2:c.4827G>A p.Glu1609= p.E1609= ENST00000427025 NM_020464.1 1609 gaG/gaA 0 +NIN UCSF GRCh37 14 51211012 51211012 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 130 48 223 0 ENST00000382041.3:c.5136G>A p.Leu1712= p.L1712= ENST00000382041 NM_016350.4 1712 ctG/ctA 0 +NKTR UCSF GRCh37 3 42679042 42679042 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 69 316 1 ENST00000232978.8:c.1846C>T p.Pro616Ser p.P616S ENST00000232978 NM_005385.3 616 Cct/Tct 0 +NLGN4X UCSF GRCh37 X 6069303 6069303 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 55 155 0 ENST00000381095.3:c.205C>T p.Pro69Ser p.P69S ENST00000381095 NM_181332.1 69 Cca/Tca 0 +NLRC3 UCSF GRCh37 16 3614574 3614574 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 59 20 109 0 ENST00000448023.2:c.505G>A p.Val169Ile p.V169I ENST00000448023 169 Gtc/Atc 0 +NLRC3 UCSF GRCh37 16 3594294 3594294 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 120 42 206 0 ENST00000448023.2:c.2945G>A p.Cys982Tyr p.C982Y ENST00000448023 982 tGt/tAt 0 +NLRP8 UCSF GRCh37 19 56467155 56467155 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 130 38 144 0 ENST00000291971.3:c.1731C>T p.Cys577= p.C577= ENST00000291971 NM_176811.2 577 tgC/tgT 0 +NOS2 UCSF GRCh37 17 26091083 26091083 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 21 8 34 0 ENST00000313735.6:c.2516C>T p.Thr839Ile p.T839I ENST00000313735 NM_000625.4 839 aCc/aTc 0 +NOTCH2 UCSF GRCh37 1 120460309 120460309 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 28 164 0 ENST00000256646.2:c.6006C>T p.Asn2002= p.N2002= ENST00000256646 NM_024408.3 2002 aaC/aaT 0 +NOTCH3 UCSF GRCh37 19 15289943 15289943 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 37 27 61 0 ENST00000263388.2:c.3611C>T p.Ala1204Val p.A1204V ENST00000263388 NM_000435.2 1204 gCa/gTa 0 +NOTCH4 UCSF GRCh37 6 32165142 32165142 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 115 13 109 0 ENST00000375023.3:c.4986G>A p.Gln1662= p.Q1662= ENST00000375023 NM_004557.3 1662 caG/caA 0 +NPL UCSF GRCh37 1 182797922 182797922 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 38 125 0 ENST00000367553.1:c.842C>T p.Pro281Leu p.P281L ENST00000367553 NM_030769.2 281 cCc/cTc 0 +NPTN UCSF GRCh37 15 73862565 73862565 + missense_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 129 50 164 0 ENST00000345330.4:c.1040T>A p.Leu347Gln p.L347Q ENST00000345330 NM_012428.3 347 cTg/cAg 0 +NPY2R UCSF GRCh37 4 156135396 156135397 + frameshift_variant Frame_Shift_Del DEL TG TG - NOVEL P21_Rec Untested WXS Illumina HiSeq 26 0 ENST00000329476.3:c.308_309del p.Cys103SerfsTer90 p.C103Sfs*90 ENST00000329476 NM_000910.2 102 cTG/c 0 +NR0B1 UCSF GRCh37 X 30327138 30327138 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 26 3 39 0 ENST00000378970.4:c.343G>A p.Val115Met p.V115M ENST00000378970 NM_000475.4 115 Gtg/Atg 0 +NRBF2 UCSF GRCh37 10 64913831 64913831 + synonymous_variant Silent SNP C C T 1000g2011may_all_0.0014 P21_Rec Untested WXS Illumina HiSeq 61 16 110 0 ENST00000277746.6:c.717C>T p.Ala239= p.A239= ENST00000277746 NM_030759.3 239 gcC/gcT 0 +NSL1 UCSF GRCh37 1 212911796 212911796 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 174 30 161 0 ENST00000366977.3:c.800G>A p.Arg267Lys p.R267K ENST00000366977 NM_015471.3 267 aGa/aAa 0 +NT5C1B-RDH14 UCSF GRCh37 2 18736478 18736478 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 137 36 217 0 ENST00000381249.3:c.990G>A p.Val330= p.V330= ENST00000381249 NM_020905.3 330 gtG/gtA 0 +NT5E UCSF GRCh37 6 86195118 86195118 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 49 32 143 0 ENST00000257770.3:c.917A>G p.Asn306Ser p.N306S ENST00000257770 NM_002526.3 306 aAt/aGt 0 +NTRK3 UCSF GRCh37 15 88678426 88678426 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 163 44 235 0 ENST00000360948.2:c.1110C>T p.His370= p.H370= ENST00000360948 NM_001012338.2 370 caC/caT 0 +NTSR2 UCSF GRCh37 2 11798712 11798712 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 42 186 0 ENST00000306928.5:c.1126C>T p.Leu376= p.L376= ENST00000306928 NM_012344.3 376 Ctg/Ttg 0 +NUDT17 UCSF GRCh37 1 145586887 145586887 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 208 58 262 0 ENST00000334513.5:c.801G>A p.Met267Ile p.M267I ENST00000334513 NM_001012758.2 267 atG/atA 0 +NUDT9 UCSF GRCh37 4 88356236 88356236 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 53 56 142 0 ENST00000302174.4:c.211C>T p.Pro71Ser p.P71S ENST00000302174 NM_024047.4 71 Cca/Tca 0 +NUMA1 UCSF GRCh37 11 71734170 71734170 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 148 41 196 0 ENST00000393695.3:c.232C>T p.Pro78Ser p.P78S ENST00000393695 NM_006185.2 78 Cca/Tca 0 +NUMB UCSF GRCh37 14 73750804 73750804 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 87 27 194 0 ENST00000355058.3:c.934C>T p.Pro312Ser p.P312S ENST00000355058 312 Ccc/Tcc 0 +NUP133 UCSF GRCh37 1 229623317 229623317 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 139 30 158 0 ENST00000261396.3:c.1238C>T p.Ser413Leu p.S413L ENST00000261396 NM_018230.2 413 tCa/tTa 0 +NUP188 UCSF GRCh37 9 131741577 131741577 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 172 22 170 0 ENST00000372577.2:c.1240C>T p.Pro414Ser p.P414S ENST00000372577 NM_015354.2 414 Cct/Tct 0 +NUP188 UCSF GRCh37 9 131721310 131721310 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 72 10 81 0 ENST00000372577.2:c.482G>A p.Cys161Tyr p.C161Y ENST00000372577 NM_015354.2 161 tGt/tAt 0 +NUP214 UCSF GRCh37 9 134064441 134064441 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 20 136 0 ENST00000359428.5:c.3497G>A p.Gly1166Glu p.G1166E ENST00000359428 NM_005085.3 1166 gGg/gAg 0 +NUP93 UCSF GRCh37 16 56863004 56863004 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 143 45 154 0 ENST00000308159.5:c.910C>T p.Pro304Ser p.P304S ENST00000308159 NM_014669.4 304 Ccc/Tcc 0 +NWD1 UCSF GRCh37 19 16875883 16875883 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 45 27 98 0 ENST00000524140.2:c.2290G>A p.Gly764Ser p.G764S ENST00000524140 NM_001007525.3 764 Ggc/Agc 0 +OBSCN UCSF GRCh37 1 228520590 228520590 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 124 37 210 0 ENST00000570156.2:c.18553G>A p.Asp6185Asn p.D6185N ENST00000570156 NM_001271223.2 6185 Gat/Aat 0 +OBSL1 UCSF GRCh37 2 220430123 220430123 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 201 55 439 0 ENST00000404537.1:c.2248T>C p.Tyr750His p.Y750H ENST00000404537 NM_015311.2 750 Tac/Cac 0 +ODZ1 UCSF GRCh37 X 123519885 123519885 + synonymous_variant Silent SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 80 46 121 0 ENST00000422452.2:c.5718G>T p.Arg1906= p.R1906= ENST00000422452 NM_001163279.1 1906 cgG/cgT 0 +OLFM1 UCSF GRCh37 9 137967582 137967582 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 13 6 22 0 ENST00000252854.4:c.30C>T p.Asp10= p.D10= ENST00000252854 NM_014279.4 10 gaC/gaT 0 +OR14J1 UCSF GRCh37 6 29275388 29275388 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 255 47 181 0 ENST00000377160.2:c.922C>T p.Leu308Phe p.L308F ENST00000377160 NM_030946.1 308 Ctt/Ttt 0 +OR1G1 UCSF GRCh37 17 3030177 3030177 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 61 173 0 ENST00000328890.2:c.669G>A p.Ser223= p.S223= ENST00000328890 NM_003555.1 223 tcG/tcA 0 +OR2B6 UCSF GRCh37 6 27925897 27925897 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 242 28 151 0 ENST00000244623.1:c.879G>A p.Arg293= p.R293= ENST00000244623 NM_012367.1 293 agG/agA 0 +OR51I2 UCSF GRCh37 11 5474787 5474787 + synonymous_variant Silent SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 22 64 155 0 ENST00000341449.2:c.69T>C p.Ser23= p.S23= ENST00000341449 NM_001004754.2 23 tcT/tcC 0 +OR52B4 UCSF GRCh37 11 4389013 4389013 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 42 39 141 0 ENST00000408920.2:c.513C>T p.Cys171= p.C171= ENST00000408920 NM_001005161.3 171 tgC/tgT 0 +OR5AS1 UCSF GRCh37 11 55798225 55798225 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 223 57 252 0 ENST00000313555.1:c.331G>A p.Glu111Lys p.E111K ENST00000313555 NM_001001921.1 111 Gag/Aag 0 +OR5B12 UCSF GRCh37 11 58206872 58206872 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 128 25 147 1 ENST00000302572.2:c.753G>A p.Gly251= p.G251= ENST00000302572 NM_001004733.2 251 ggG/ggA 0 +OR5K3 UCSF GRCh37 3 98110426 98110426 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 60 12 43 0 ENST00000383695.1:c.917G>A p.Arg306Lys p.R306K ENST00000383695 NM_001005516.1 306 aGa/aAa 0 +OR8B4 UCSF GRCh37 11 124293998 124293998 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 51 23 133 0 ENST00000356130.3:c.770C>T p.Thr257Ile p.T257I ENST00000356130 NM_001005196.1 257 aCc/aTc 0 +OR8J1 UCSF GRCh37 11 56128341 56128341 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 168 46 183 0 ENST00000303039.3:c.619G>A p.Val207Met p.V207M ENST00000303039 NM_001005205.2 207 Gtg/Atg 0 +ORC1 UCSF GRCh37 1 52854139 52854139 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 280 33 370 0 ENST00000371568.3:c.1358C>T p.Thr453Ile p.T453I ENST00000371568 NM_001190818.1 453 aCc/aTc 0 +OSGIN2 UCSF GRCh37 8 90937737 90937737 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 27 92 0 ENST00000451899.2:c.1627G>A p.Gly543Arg p.G543R ENST00000451899 NM_001126111.1 543 Gga/Aga 0 +OTOGL UCSF GRCh37 12 80645976 80645976 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 262 35 424 0 ENST00000458043.2:c.1253C>T p.Pro418Leu p.P418L ENST00000458043 NM_173591.3 418 cCa/cTa 0 +OTOS UCSF GRCh37 2 241078726 241078726 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 129 18 185 0 ENST00000391989.2:c.131C>T p.Thr44Ile p.T44I ENST00000391989 44 aCc/aTc 0 +OVCH1 UCSF GRCh37 12 29630283 29630283 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 496 106 518 1 ENST00000318184.5:c.1237T>C p.Ser413Pro p.S413P ENST00000318184 NM_183378.2 413 Tca/Cca 0 +OXA1L UCSF GRCh37 14 23240692 23240692 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 212 62 327 0 ENST00000285848.5:c.1413G>A p.Lys471= p.K471= ENST00000285848 NM_005015.3 471 aaG/aaA 0 +P2RY12 UCSF GRCh37 3 151055634 151055634 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 138 41 159 0 ENST00000302632.3:c.1000G>A p.Gly334Ser p.G334S ENST00000302632 NM_022788.4 334 Ggt/Agt 0 +P2RY12 UCSF GRCh37 3 151056491 151056491 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 97 19 89 0 ENST00000302632.3:c.143G>A p.Arg48Lys p.R48K ENST00000302632 NM_022788.4 48 aGg/aAg 0 +PACSIN3 UCSF GRCh37 11 47204082 47204082 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 55 41 159 0 ENST00000539589.1:c.83G>A p.Arg28Gln p.R28Q ENST00000539589 NM_001184975.1 28 cGg/cAg 0 +PADI1 UCSF GRCh37 1 17563920 17563920 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 80 25 128 0 ENST00000375471.4:c.1425G>A p.Glu475= p.E475= ENST00000375471 NM_013358.2 475 gaG/gaA 0 +PAH UCSF GRCh37 12 103306658 103306658 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec Untested WXS Illumina HiSeq 100 38 174 0 ENST00000553106.1:c.79G>C p.Asp27His p.D27H ENST00000553106 NM_000277.1 27 Gac/Cac 0 +PAPPA2 UCSF GRCh37 1 176525700 176525700 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 291 66 376 1 ENST00000367662.3:c.242C>T p.Pro81Leu p.P81L ENST00000367662 NM_020318.2 81 cCc/cTc 0 +PAPSS2 UCSF GRCh37 10 89503288 89503288 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 124 18 242 0 ENST00000456849.1:c.1381G>A p.Asp461Asn p.D461N ENST00000456849 NM_001015880.1 461 Gac/Aac 0 +PC UCSF GRCh37 11 66620748 66620748 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 135 16 175 0 ENST00000393960.1:c.1475C>T p.Pro492Leu p.P492L ENST00000393960 NM_001040716.1 492 cCt/cTt 0 +PCDHB13 UCSF GRCh37 5 140595033 140595033 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 149 99 537 0 ENST00000341948.4:c.1338C>T p.Asp446= p.D446= ENST00000341948 NM_018933.2 446 gaC/gaT 0 +PCDP1 UCSF GRCh37 2 120362788 120362788 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 60 13 114 0 ENST00000413369.3:c.1056G>A p.Thr352= p.T352= ENST00000413369 NM_001271049.1 352 acG/acA 0 +PCGF5 UCSF GRCh37 10 93038059 93038059 + missense_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 62 17 101 0 ENST00000336126.5:c.757A>G p.Ile253Val p.I253V ENST00000336126 NM_032373.4 253 Att/Gtt 0 +PCSK2 UCSF GRCh37 20 17208024 17208024 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 53 41 106 0 ENST00000262545.2:c.74C>A p.Ala25Asp p.A25D ENST00000262545 NM_002594.3 25 gCt/gAt 0 +PDE11A UCSF GRCh37 2 178576529 178576529 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 35 11 84 0 ENST00000286063.6:c.2121C>T p.Asp707= p.D707= ENST00000286063 NM_016953.3 707 gaC/gaT 0 +PDGFRA UCSF GRCh37 4 55131142 55131142 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 253 689 207 0 ENST00000257290.5:c.685G>A p.Glu229Lys p.E229K ENST00000257290 NM_006206.4 229 Gaa/Aaa 0 +PDGFRB UCSF GRCh37 5 149501589 149501589 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 53 16 134 0 ENST00000261799.4:c.2198C>T p.Thr733Ile p.T733I ENST00000261799 NM_002609.3 733 aCc/aTc 0 +PDPR UCSF GRCh37 16 70176162 70176162 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 247 33 310 0 ENST00000288050.4:c.1341C>T p.Pro447= p.P447= ENST00000288050 NM_017990.3 447 ccC/ccT 0 +PEAK1 UCSF GRCh37 15 77450873 77450873 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 120 33 152 0 ENST00000560626.2:c.3303C>T p.Asn1101= p.N1101= ENST00000560626 1101 aaC/aaT 0 +PENK UCSF GRCh37 8 57354046 57354046 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 175 67 228 0 ENST00000314922.3:c.589C>T p.Pro197Ser p.P197S ENST00000314922 NM_006211.3 197 Ccc/Tcc 0 +PER3 UCSF GRCh37 1 7886742 7886742 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 59 25 99 0 ENST00000361923.2:c.2136G>A p.Arg712= p.R712= ENST00000361923 NM_016831.1 712 agG/agA 0 +PEX5 UCSF GRCh37 12 7360673 7360673 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 19 110 0 ENST00000434354.2:c.1223G>A p.Arg408Gln p.R408Q ENST00000434354 NM_001131023.1 408 cGg/cAg 0 +PFAS UCSF GRCh37 17 8168739 8168739 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 142 44 224 0 ENST00000314666.6:c.2414C>T p.Ser805Phe p.S805F ENST00000314666 NM_012393.2 805 tCc/tTc 0 +PFAS UCSF GRCh37 17 8172160 8172160 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 55 18 90 0 ENST00000314666.6:c.3692G>A p.Ser1231Asn p.S1231N ENST00000314666 NM_012393.2 1231 aGt/aAt 0 +PFKFB2 UCSF GRCh37 1 207240875 207240875 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 122 41 177 0 ENST00000367080.3:c.664G>A p.Gly222Ser p.G222S ENST00000367080 NM_006212.2 222 Ggc/Agc 0 +PFKFB4 UCSF GRCh37 3 48576744 48576744 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 36 11 65 0 ENST00000232375.3:c.454-1G>A p.X152_splice ENST00000232375 NM_004567.2 0 +PGP UCSF GRCh37 16 2263816 2263816 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 179 41 243 0 ENST00000333503.7:c.879G>A p.Gln293= p.Q293= ENST00000333503 NM_001042371.2 293 caG/caA 0 +PHF21A UCSF GRCh37 11 45955610 45955610 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 42 5 79 0 ENST00000418153.2:c.1952C>T p.Pro651Leu p.P651L ENST00000418153 651 cCc/cTc 0 +PHF21B UCSF GRCh37 22 45281750 45281750 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 147 48 205 0 ENST00000313237.5:c.1266C>T p.His422= p.H422= ENST00000313237 NM_138415.4 422 caC/caT 0 +PHLDB1 UCSF GRCh37 11 118495696 118495696 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 48 34 168 0 ENST00000361417.2:c.402C>T p.His134= p.H134= ENST00000361417 NM_015157.3 134 caC/caT 0 +PIGT UCSF GRCh37 20 44052855 44052855 + splice_acceptor_variant Splice_Site SNP G G A snp132_rs112243674 P21_Rec Untested WXS Illumina HiSeq 79 24 140 0 ENST00000279036.6:c.1235-1G>A p.X412_splice ENST00000279036 NM_015937.5 0 +PIKFYVE UCSF GRCh37 2 209198074 209198074 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 95 11 142 0 ENST00000264380.4:c.3999G>A p.Trp1333Ter p.W1333* ENST00000264380 NM_015040.3 1333 tgG/tgA 0 +PIWIL2 UCSF GRCh37 8 22171841 22171841 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 34 10 43 0 ENST00000356766.6:c.1990G>A p.Gly664Arg p.G664R ENST00000356766 NM_018068.3 664 Ggg/Agg 0 +PKD1 UCSF GRCh37 16 2153526 2153526 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 248 75 463 0 ENST00000262304.4:c.8532C>T p.Val2844= p.V2844= ENST00000262304 NM_001009944.2 2844 gtC/gtT 0 +PKHD1L1 UCSF GRCh37 8 110498908 110498908 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 551 75 508 0 ENST00000378402.5:c.9738G>A p.Glu3246= p.E3246= ENST00000378402 NM_177531.4 3246 gaG/gaA 0 +PKLR UCSF GRCh37 1 155269984 155269984 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 62 18 79 0 ENST00000342741.4:c.188C>T p.Ala63Val p.A63V ENST00000342741 NM_000298.5 63 gCt/gTt 0 +PKN2 UCSF GRCh37 1 89294219 89294219 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 16 75 0 ENST00000370521.3:c.2475C>T p.Ala825= p.A825= ENST00000370521 NM_006256.2 825 gcC/gcT 0 +PLEKHG2 UCSF GRCh37 19 39904836 39904836 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 17 6 30 0 ENST00000409794.3:c.109+1G>A p.X37_splice ENST00000409794 NM_022835.2 0 +PLEKHG3 UCSF GRCh37 14 65194574 65194574 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 24 10 51 0 ENST00000247226.7:c.225C>T p.Leu75= p.L75= ENST00000247226 NM_015549.1 75 ctC/ctT 0 +PLEKHM1 UCSF GRCh37 17 43552712 43552712 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 154 40 268 0 ENST00000430334.3:c.677C>T p.Ser226Phe p.S226F ENST00000430334 NM_014798.2 226 tCt/tTt 0 +PLOD1 UCSF GRCh37 1 12032969 12032969 + missense_variant Missense_Mutation SNP A A T NOVEL P21_Rec Untested WXS Illumina HiSeq 119 25 184 0 ENST00000196061.4:c.1943A>T p.Asp648Val p.D648V ENST00000196061 NM_000302.3 648 gAt/gTt 0 +PLSCR3 UCSF GRCh37 17 7296919 7296919 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 159 40 202 0 ENST00000535512.1:c.243+1G>A p.X81_splice ENST00000535512 0 +PLXNA1 UCSF GRCh37 3 126741603 126741603 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 170 39 301 2 ENST00000393409.2:c.4304C>T p.Ser1435Leu p.S1435L ENST00000393409 NM_032242.3 1435 tCg/tTg 0 +PML UCSF GRCh37 15 74290735 74290735 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 20 118 0 ENST00000268058.3:c.520G>A p.Val174Met p.V174M ENST00000268058 NM_033238.2 174 Gtg/Atg 0 +POLI UCSF GRCh37 18 51800296 51800296 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 115 47 174 0 ENST00000579534.1:c.242G>A p.Gly81Glu p.G81E ENST00000579534 NM_007195.2 81 gGg/gAg 0 +POLK UCSF GRCh37 5 74892598 74892598 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 19 74 0 ENST00000241436.4:c.2080G>A p.Glu694Lys p.E694K ENST00000241436 NM_016218.2 694 Gaa/Aaa 0 +POLN UCSF GRCh37 4 2082740 2082740 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 139 31 191 0 ENST00000511885.2:c.2332C>T p.Leu778= p.L778= ENST00000511885 778 Ctg/Ttg 0 +PON2 UCSF GRCh37 7 95039262 95039262 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 157 46 277 0 ENST00000222572.3:c.646G>A p.Ala216Thr p.A216T ENST00000222572 216 Gca/Aca 0 +POSTN UCSF GRCh37 13 38161957 38161957 + splice_donor_variant Splice_Site SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 40 33 96 0 ENST00000379747.4:c.606+2T>C p.X202_splice ENST00000379747 NM_006475.2 0 +PPFIA4 UCSF GRCh37 1 203022984 203022984 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 21 8 30 0 ENST00000272198.6:c.206G>A p.Gly69Asp p.G69D ENST00000272198 NM_015053.1 69 gGt/gAt 0 +PPFIBP1 UCSF GRCh37 12 27841986 27841986 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 216 95 245 0 ENST00000318304.8:c.2553G>T p.Gln851His p.Q851H ENST00000318304 NM_177444.2 851 caG/caT 0 +PPIB UCSF GRCh37 15 64448950 64448950 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 268 96 434 0 ENST00000300026.3:c.502G>A p.Val168Met p.V168M ENST00000300026 NM_000942.4 168 Gtg/Atg 0 +PPM1B UCSF GRCh37 2 44445214 44445214 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 54 22 73 0 ENST00000282412.4:c.1073G>A p.Gly358Asp p.G358D ENST00000282412 NM_002706.4 358 gGc/gAc 0 +PPP1R13L UCSF GRCh37 19 45889151 45889151 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 6 37 0 ENST00000418234.2:c.2012C>T p.Ala671Val p.A671V ENST00000418234 NM_001142502.1 671 gCc/gTc 0 +PPP2R1A UCSF GRCh37 19 52715981 52715981 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 131 47 184 0 ENST00000322088.6:c.546G>A p.Arg182= p.R182= ENST00000322088 NM_014225.5 182 cgG/cgA 0 +PPP2R2C UCSF GRCh37 4 6325083 6325083 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 93 23 152 0 ENST00000335585.5:c.1290C>T p.Ala430= p.A430= ENST00000335585 NM_181876.2 430 gcC/gcT 0 +PPWD1 UCSF GRCh37 5 64867978 64867978 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 142 39 162 0 ENST00000261308.5:c.834G>A p.Lys278= p.K278= ENST00000261308 NM_001278927.1 278 aaG/aaA 0 +PRG2 UCSF GRCh37 11 57156716 57156716 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 127 26 189 0 ENST00000311862.5:c.133G>A p.Glu45Lys p.E45K ENST00000311862 NM_002728.4 45 Gag/Aag 0 +PRKCB UCSF GRCh37 16 24135240 24135240 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 174 58 357 0 ENST00000303531.7:c.1003G>A p.Asp335Asn p.D335N ENST00000303531 NM_002738.6 335 Gac/Aac 0 +PRKD1 UCSF GRCh37 14 30194858 30194858 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 90 40 177 0 ENST00000331968.5:c.287G>A p.Gly96Glu p.G96E ENST00000331968 NM_002742.2 96 gGa/gAa 0 +PRKDC UCSF GRCh37 8 48792051 48792051 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 93 14 93 0 ENST00000314191.2:c.5232+1G>A p.X1744_splice ENST00000314191 NM_006904.6 0 +PRKDC UCSF GRCh37 8 48842573 48842573 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 122 32 131 0 ENST00000314191.2:c.1893-1G>A p.X631_splice ENST00000314191 NM_006904.6 0 +PRODH UCSF GRCh37 22 18910629 18910629 + missense_variant,splice_region_variant Missense_Mutation SNP A A G NOVEL P21_Rec Untested WXS Illumina HiSeq 131 41 201 0 ENST00000357068.6:c.731T>C p.Leu244Pro p.L244P ENST00000357068 NM_016335.4 244 cTg/cCg 0 +PRPF40B UCSF GRCh37 12 50027730 50027730 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 18 115 0 ENST00000548825.2:c.667C>T p.Pro223Ser p.P223S ENST00000548825 NM_001031698.2 223 Ccc/Tcc 0 +PRPF40B UCSF GRCh37 12 50035712 50035712 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 22 109 0 ENST00000548825.2:c.1789G>A p.Val597Met p.V597M ENST00000548825 NM_001031698.2 597 Gtg/Atg 0 +PRR12 UCSF GRCh37 19 50098109 50098109 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 15 5 20 0 ENST00000418929.2:c.517C>T p.Pro173Ser p.P173S ENST00000418929 NM_020719.1 173 Ccc/Tcc 0 +PRRC2C UCSF GRCh37 1 171510733 171510733 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.0061,snp132_rs74122867 P21_Rec Untested WXS Illumina HiSeq 192 45 241 0 ENST00000338920.4:c.4122G>A p.Gln1374= p.Q1374= ENST00000338920 NM_015172.3 1374 caG/caA 0 +PRSS3 UCSF GRCh37 9 33797843 33797843 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 418 92 659 0 ENST00000361005.5:c.388C>T p.Leu130= p.L130= ENST00000361005 NM_007343.3 130 Ctg/Ttg 0 +PSAPL1 UCSF GRCh37 4 7435437 7435437 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 148 47 233 0 ENST00000319098.4:c.1170G>A p.Glu390= p.E390= ENST00000319098 NM_001085382.1 390 gaG/gaA 0 +PSD3 UCSF GRCh37 8 18725432 18725432 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 231 62 310 0 ENST00000327040.8:c.1386G>A p.Glu462= p.E462= ENST00000327040 NM_015310.3 462 gaG/gaA 0 +PSMB1 UCSF GRCh37 6 170844403 170844403 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 63 33 213 0 ENST00000262193.6:c.631G>A p.Ala211Thr p.A211T ENST00000262193 NM_002793.3 211 Gct/Act 0 +PTCH1 UCSF GRCh37 9 98209333 98209333 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 109 27 174 0 ENST00000331920.6:c.4205C>T p.Pro1402Leu p.P1402L ENST00000331920 NM_000264.3 1402 cCt/cTt 0 +PTCHD2 UCSF GRCh37 1 11561820 11561820 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 25 14 53 0 ENST00000294484.6:c.771C>T p.Asp257= p.D257= ENST00000294484 NM_020780.1 257 gaC/gaT 0 +PTPLAD2 UCSF GRCh37 9 21026605 21026605 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 95 37 200 0 ENST00000495827.2:c.260G>A p.Arg87Lys p.R87K ENST00000495827 NM_001010915.3 87 aGg/aAg 0 +PTPRN2 UCSF GRCh37 7 157926724 157926724 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 80 24 166 0 ENST00000389418.4:c.1201G>A p.Gly401Ser p.G401S ENST00000389418 NM_002847.3 401 Ggc/Agc 0 +PUM2 UCSF GRCh37 2 20478577 20478577 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 114 57 218 0 ENST00000338086.5:c.1724G>A p.Gly575Asp p.G575D ENST00000338086 NM_015317.1 575 gGc/gAc 0 +PXDN UCSF GRCh37 2 1677534 1677534 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 302 93 630 0 ENST00000252804.4:c.899G>A p.Gly300Glu p.G300E ENST00000252804 NM_012293.1 300 gGg/gAg 0 +QSOX2 UCSF GRCh37 9 139108532 139108532 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 70 21 102 0 ENST00000358701.5:c.1123G>A p.Glu375Lys p.E375K ENST00000358701 NM_181701.3 375 Gag/Aag 0 +R3HCC1 UCSF GRCh37 8 23147752 23147752 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 18 5 16 0 ENST00000265806.6:c.61C>T p.Leu21= p.L21= ENST00000265806 NM_001136108.1 21 Ctg/Ttg 0 +RAB3GAP2 UCSF GRCh37 1 220364547 220364547 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 99 36 159 0 ENST00000358951.2:c.1350C>T p.Ser450= p.S450= ENST00000358951 NM_012414.3 450 tcC/tcT 0 +RABGAP1L UCSF GRCh37 1 174957826 174957826 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 78 19 82 0 ENST00000325589.5:c.775G>A p.Gly259Ser p.G259S ENST00000325589 259 Ggt/Agt 0 +RAD17 UCSF GRCh37 5 68692336 68692336 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 51 14 61 0 ENST00000509734.1:c.1568C>T p.Pro523Leu p.P523L ENST00000509734 523 cCc/cTc 0 +RAD21 UCSF GRCh37 8 117866648 117866648 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 309 38 266 0 ENST00000297338.2:c.997G>A p.Asp333Asn p.D333N ENST00000297338 NM_006265.2 333 Gat/Aat 0 +RAD51 UCSF GRCh37 15 40991018 40991018 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 32 155 0 ENST00000267868.3:c.62G>A p.Gly21Asp p.G21D ENST00000267868 NM_002875.4 21 gGc/gAc 0 +RAD54L2 UCSF GRCh37 3 51672310 51672310 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 136 50 150 0 ENST00000409535.2:c.1833C>T p.Pro611= p.P611= ENST00000409535 NM_015106.2 611 ccC/ccT 0 +RALGAPB UCSF GRCh37 20 37137727 37137727 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 50 246 0 ENST00000262879.6:c.748C>T p.Arg250Cys p.R250C ENST00000262879 250 Cgc/Tgc 0 +RALGDS UCSF GRCh37 9 135974021 135974021 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 13 127 0 ENST00000372050.3:c.2698C>T p.Pro900Ser p.P900S ENST00000372050 NM_006266.3 900 Cct/Tct 0 +RANBP3 UCSF GRCh37 19 5923259 5923259 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 98 15 139 0 ENST00000340578.6:c.1155G>A p.Leu385= p.L385= ENST00000340578 NM_007322.2 385 ttG/ttA 0 +RAP1GAP2 UCSF GRCh37 17 2908700 2908700 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 247 158 544 0 ENST00000254695.8:c.1238G>T p.Gly413Val p.G413V ENST00000254695 NM_015085.4 413 gGt/gTt 0 +RAPGEF5 UCSF GRCh37 7 22349610 22349610 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 144 64 270 0 ENST00000344041.6:c.30G>A p.Leu10= p.L10= ENST00000344041 NM_012294.3 10 ctG/ctA 0 +RASGRF1 UCSF GRCh37 15 79382719 79382719 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 246 61 324 0 ENST00000419573.3:c.122C>T p.Thr41Ile p.T41I ENST00000419573 NM_002891.4 41 aCc/aTc 0 +RASGRF1 UCSF GRCh37 15 79298560 79298560 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 37 240 0 ENST00000419573.3:c.2082C>T p.Ile694= p.I694= ENST00000419573 NM_002891.4 694 atC/atT 0 +RBAK UCSF GRCh37 7 5104026 5104026 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 132 56 231 0 ENST00000396912.1:c.939G>A p.Glu313= p.E313= ENST00000396912 NM_021163.3 313 gaG/gaA 0 +RBM12 UCSF GRCh37 20 34241916 34241916 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 37 160 0 ENST00000374114.3:c.1329C>T p.Asn443= p.N443= ENST00000374114 NM_001198838.1 443 aaC/aaT 0 +RBM15 UCSF GRCh37 1 110884780 110884780 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 145 55 201 0 ENST00000369784.3:c.2753G>A p.Gly918Glu p.G918E ENST00000369784 NM_022768.4 918 gGg/gAg 0 +RBM17 UCSF GRCh37 10 6151953 6151953 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 214 33 172 0 ENST00000446108.1:c.567C>T p.Pro189= p.P189= ENST00000446108 NM_001145547.1 189 ccC/ccT 0 +RBM26 UCSF GRCh37 13 79928639 79928639 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 8 123 0 ENST00000267229.7:c.1912G>A p.Gly638Ser p.G638S ENST00000267229 NM_022118.3 638 Ggt/Agt 0 +RBMS3 UCSF GRCh37 3 29476270 29476270 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 137 37 182 1 ENST00000383767.2:c.112C>A p.Pro38Thr p.P38T ENST00000383767 38 Ccc/Acc 0 +RC3H2 UCSF GRCh37 9 125659702 125659702 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 96 25 133 0 ENST00000373670.1:c.87C>T p.Ile29= p.I29= ENST00000373670 29 atC/atT 0 +RCSD1 UCSF GRCh37 1 167666688 167666688 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 19 4 31 0 ENST00000367854.3:c.827C>T p.Pro276Leu p.P276L ENST00000367854 NM_052862.3 276 cCg/cTg 0 +REV1 UCSF GRCh37 2 100024589 100024589 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 148 18 174 0 ENST00000258428.3:c.2350G>A p.Val784Ile p.V784I ENST00000258428 NM_001037872.1 784 Gta/Ata 0 +REV3L UCSF GRCh37 6 111695087 111695087 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 107 80 244 0 ENST00000358835.3:c.4471G>A p.Val1491Ile p.V1491I ENST00000358835 1491 Gta/Ata 0 +RG9MTD3 UCSF GRCh37 9 37770683 37770683 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 56 17 91 0 ENST00000297994.3:c.667G>A p.Asp223Asn p.D223N ENST00000297994 NM_144964.2 223 Gat/Aat 0 +RGS12 UCSF GRCh37 4 3318901 3318901 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 177 45 247 1 ENST00000344733.5:c.1004C>T p.Thr335Ile p.T335I ENST00000344733 NM_198229.2 335 aCt/aTt 0 +RGS14 UCSF GRCh37 5 176795777 176795777 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 15 59 136 0 ENST00000408923.3:c.909C>T p.Tyr303= p.Y303= ENST00000408923 NM_006480.4 303 taC/taT 0 +RHAG UCSF GRCh37 6 49604443 49604443 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0042,snp132_rs114042395 P21_Rec Untested WXS Illumina HiSeq 368 52 259 0 ENST00000371175.4:c.83C>T p.Thr28Met p.T28M ENST00000371175 NM_000324.2 28 aCg/aTg 0 +RHBDF2 UCSF GRCh37 17 74470598 74470598 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 67 27 113 0 ENST00000313080.4:c.1408G>A p.Gly470Arg p.G470R ENST00000313080 NM_024599.5 470 Ggg/Agg 0 +RHOB UCSF GRCh37 2 20647261 20647261 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 34 15 84 0 ENST00000272233.4:c.35G>A p.Gly12Asp p.G12D ENST00000272233 NM_004040.2 12 gGc/gAc 0 +RHOT2 UCSF GRCh37 16 722944 722944 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 98 36 153 0 ENST00000315082.4:c.1544G>A p.Gly515Glu p.G515E ENST00000315082 NM_138769.2 515 gGg/gAg 0 +RIMS1 UCSF GRCh37 6 73110251 73110251 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 119 35 332 0 ENST00000521978.1:c.4914G>A p.Val1638= p.V1638= ENST00000521978 NM_014989.5 1638 gtG/gtA 0 +RIN2 UCSF GRCh37 20 19956118 19956118 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 141 32 259 0 ENST00000255006.6:c.1596G>A p.Arg532= p.R532= ENST00000255006 NM_018993.3 532 agG/agA 0 +RNF19B UCSF GRCh37 1 33407982 33407982 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 88 37 132 0 ENST00000373456.7:c.1484C>T p.Thr495Ile p.T495I ENST00000373456 NM_153341.2 495 aCt/aTt 0 +RNF20 UCSF GRCh37 9 104303258 104303258 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 76 31 134 0 ENST00000389120.3:c.628+1G>A p.X210_splice ENST00000389120 NM_019592.6 0 +RNF212 UCSF GRCh37 4 1087248 1087248 + intron_variant Intron SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 53 7 66 0 ENST00000433731.2:c.247-2622G>A *83* ENST00000433731 0 +RNF26 UCSF GRCh37 11 119206973 119206973 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 91 12 172 0 ENST00000311413.4:c.1141G>A p.Val381Ile p.V381I ENST00000311413 NM_032015.4 381 Gtc/Atc 0 +RNF43 UCSF GRCh37 17 56434896 56434896 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 118 40 186 1 ENST00000407977.2:c.2241G>A p.Trp747Ter p.W747* ENST00000407977 747 tgG/tgA 0 +RNGTT UCSF GRCh37 6 89673110 89673110 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 21 9 59 0 ENST00000369485.4:c.19C>T p.Pro7Ser p.P7S ENST00000369485 NM_003800.3 7 Ccg/Tcg 0 +RNMTL1 UCSF GRCh37 17 686449 686449 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 149 26 173 0 ENST00000304478.4:c.441C>T p.Ser147= p.S147= ENST00000304478 NM_018146.2 147 agC/agT 0 +ROBO2 UCSF GRCh37 3 77638066 77638066 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 114 82 181 0 ENST00000487694.3:c.2713G>A p.Gly905Arg p.G905R ENST00000487694 NM_001128929.2 905 Gga/Aga 0 +ROR2 UCSF GRCh37 9 94487067 94487067 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 109 24 171 0 ENST00000375708.3:c.1709C>T p.Pro570Leu p.P570L ENST00000375708 NM_004560.3 570 cCg/cTg 0 +RPP25 UCSF GRCh37 15 75248436 75248436 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 23 9 23 0 ENST00000322177.5:c.489G>A p.Pro163= p.P163= ENST00000322177 NM_017793.2 163 ccG/ccA 0 +RREB1 UCSF GRCh37 6 7248786 7248786 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 20 148 0 ENST00000379938.2:c.4814C>T p.Thr1605Ile p.T1605I ENST00000379938 NM_001003700.1 1605 aCc/aTc 0 +RRM2 UCSF GRCh37 2 10263567 10263567 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 45 18 98 0 ENST00000360566.2:c.408C>T p.Asn136= p.N136= ENST00000360566 NM_001165931.1 136 aaC/aaT 0 +RRP1B UCSF GRCh37 21 45103245 45103245 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 98 13 94 0 ENST00000340648.4:c.882C>T p.Pro294= p.P294= ENST00000340648 NM_015056.2 294 ccC/ccT 0 +RRP36 UCSF GRCh37 6 42996950 42996950 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 515 61 297 0 ENST00000244496.5:c.764C>T p.Pro255Leu p.P255L ENST00000244496 NM_033112.2 255 cCt/cTt 0 +RTN4RL2 UCSF GRCh37 11 57235467 57235467 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 112 39 182 0 ENST00000335099.3:c.417C>T p.Tyr139= p.Y139= ENST00000335099 NM_178570.2 139 taC/taT 0 +RUNDC1 UCSF GRCh37 17 41143444 41143444 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 132 34 218 0 ENST00000361677.1:c.1553C>T p.Thr518Ile p.T518I ENST00000361677 NM_173079.2 518 aCa/aTa 0 +RYR3 UCSF GRCh37 15 34049710 34049710 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 53 11 85 0 ENST00000389232.4:c.8618G>A p.Ser2873Asn p.S2873N ENST00000389232 NM_001036.3 2873 aGt/aAt 0 +SAFB2 UCSF GRCh37 19 5594077 5594077 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 11 4 25 0 ENST00000252542.4:c.2032G>A p.Glu678Lys p.E678K ENST00000252542 NM_014649.2 678 Gag/Aag 0 +SAMD8 UCSF GRCh37 10 76936330 76936330 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 33 194 0 ENST00000542569.1:c.1128G>A p.Arg376= p.R376= ENST00000542569 NM_144660.2 376 agG/agA 0 +SAP130 UCSF GRCh37 2 128750879 128750879 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 185 51 280 0 ENST00000357702.5:c.1437G>A p.Pro479= p.P479= ENST00000357702 NM_001145928.1 479 ccG/ccA 0 +SARS UCSF GRCh37 1 109777933 109777933 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 160 55 234 0 ENST00000234677.2:c.849G>A p.Glu283= p.E283= ENST00000234677 NM_006513.3 283 gaG/gaA 0 +SART1 UCSF GRCh37 11 65746346 65746346 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 146 26 187 0 ENST00000312397.5:c.2345C>T p.Pro782Leu p.P782L ENST00000312397 NM_005146.4 782 cCc/cTc 0 +SART1 UCSF GRCh37 11 65743865 65743865 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 8 35 0 ENST00000312397.5:c.1573-1G>A p.X525_splice ENST00000312397 NM_005146.4 0 +SBNO1 UCSF GRCh37 12 123798194 123798194 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 32 18 45 0 ENST00000420886.2:c.3193C>T p.Pro1065Ser p.P1065S ENST00000420886 NM_001167856.1 1065 Cca/Tca 0 +SCAF11 UCSF GRCh37 12 46357889 46357889 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 23 7 30 0 ENST00000369367.3:c.61+1G>A p.X21_splice ENST00000369367 NM_004719.2 0 +SCAF4 UCSF GRCh37 21 33058004 33058004 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 53 62 0 ENST00000286835.7:c.2086C>T p.Gln696Ter p.Q696* ENST00000286835 NM_020706.2 696 Cag/Tag 0 +SCAF8 UCSF GRCh37 6 155145444 155145444 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 45 221 0 ENST00000367178.3:c.2003C>T p.Pro668Leu p.P668L ENST00000367178 NM_014892.3 668 cCt/cTt 0 +SCARA3 UCSF GRCh37 8 27516386 27516386 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 64 9 95 0 ENST00000301904.3:c.699G>T p.Trp233Cys p.W233C ENST00000301904 NM_016240.2 233 tgG/tgT 0 +SCN11A UCSF GRCh37 3 38924723 38924723 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 13 136 0 ENST00000302328.3:c.3219+1G>A p.X1073_splice ENST00000302328 NM_014139.2 0 +SCN3B UCSF GRCh37 11 123513277 123513277 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 87 13 190 0 ENST00000392770.2:c.322C>T p.Leu108Phe p.L108F ENST00000392770 NM_018400.3 108 Ctc/Ttc 0 +SCNM1 UCSF GRCh37 1 151139625 151139625 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 251 58 314 0 ENST00000368905.4:c.240G>A p.Gln80= p.Q80= ENST00000368905 NM_024041.3 80 caG/caA 0 +SCPEP1 UCSF GRCh37 17 55078335 55078335 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 187 58 266 0 ENST00000262288.3:c.1114C>T p.Leu372Phe p.L372F ENST00000262288 NM_021626.2 372 Ctc/Ttc 0 +SCUBE2 UCSF GRCh37 11 9052337 9052337 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 99 41 270 0 ENST00000520467.1:c.2138G>A p.Gly713Glu p.G713E ENST00000520467 NM_020974.2 713 gGa/gAa 0 +SCYL2 UCSF GRCh37 12 100723044 100723044 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 69 12 77 0 ENST00000360820.2:c.1708G>A p.Val570Met p.V570M ENST00000360820 NM_017988.4 570 Gtg/Atg 0 +SCYL3 UCSF GRCh37 1 169847817 169847817 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 151 39 203 0 ENST00000367772.4:c.309G>A p.Gly103= p.G103= ENST00000367772 NM_181093.3 103 ggG/ggA 0 +SEMA6A UCSF GRCh37 5 115808768 115808768 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 199 54 225 0 ENST00000343348.6:c.1729+1G>A p.X577_splice ENST00000343348 NM_020796.3 0 +SEMA6A UCSF GRCh37 5 115814408 115814408 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 217 66 292 0 ENST00000343348.6:c.1257C>T p.Arg419= p.R419= ENST00000343348 NM_020796.3 419 cgC/cgT 0 +SERTAD1 UCSF GRCh37 19 40929159 40929159 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 18 3 27 0 ENST00000357949.4:c.295G>A p.Val99Met p.V99M ENST00000357949 NM_013376.3 99 Gtg/Atg 0 +SETD5 UCSF GRCh37 3 9512549 9512549 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 299 61 247 0 ENST00000402198.1:c.3131C>T p.Pro1044Leu p.P1044L ENST00000402198 NM_001080517.1 1044 cCt/cTt 0 +SETD5 UCSF GRCh37 3 9485095 9485095 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 92 14 90 0 ENST00000402198.1:c.1181G>A p.Ser394Asn p.S394N ENST00000402198 NM_001080517.1 394 aGt/aAt 0 +SETD6 UCSF GRCh37 16 58550503 58550503 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 68 22 102 0 ENST00000219315.4:c.598C>T p.Pro200Ser p.P200S ENST00000219315 200 Ccc/Tcc 0 +SF3B3 UCSF GRCh37 16 70601401 70601401 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 106 21 123 1 ENST00000302516.5:c.2914C>T p.Leu972= p.L972= ENST00000302516 NM_012426.4 972 Ctg/Ttg 0 +SFXN2 UCSF GRCh37 10 104491966 104491966 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 62 29 152 0 ENST00000369893.5:c.712C>T p.Pro238Ser p.P238S ENST00000369893 NM_178858.4 238 Cct/Tct 0 +SGOL1 UCSF GRCh37 3 20216193 20216193 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 87 23 112 0 ENST00000263753.4:c.830C>T p.Ser277Phe p.S277F ENST00000263753 NM_001012410.3 277 tCt/tTt 0 +SGSM3 UCSF GRCh37 22 40803205 40803205 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 93 22 126 0 ENST00000248929.9:c.1241G>A p.Gly414Glu p.G414E ENST00000248929 NM_015705.4 414 gGg/gAg 0 +SHANK2 UCSF GRCh37 11 70332736 70332736 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 25 122 0 ENST00000338508.4:c.3665C>T p.Ser1222Phe p.S1222F ENST00000338508 1222 tCc/tTc 0 +SHBG UCSF GRCh37 17 7534144 7534144 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 9 121 0 ENST00000380450.4:c.350C>T p.Thr117Met p.T117M ENST00000380450 NM_001040.3 117 aCg/aTg 0 +SHMT2 UCSF GRCh37 12 57627415 57627415 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 33 166 0 ENST00000328923.3:c.1093C>T p.Leu365= p.L365= ENST00000328923 NM_005412.5 365 Ctg/Ttg 0 +SI UCSF GRCh37 3 164777734 164777734 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 257 77 302 0 ENST00000264382.3:c.1102G>A p.Val368Met p.V368M ENST00000264382 NM_001041.3 368 Gtg/Atg 0 +SIAH3 UCSF GRCh37 13 46358136 46358136 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 23 18 114 0 ENST00000400405.2:c.192C>T p.His64= p.H64= ENST00000400405 NM_198849.2 64 caC/caT 0 +SIDT1 UCSF GRCh37 3 113331041 113331041 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 85 27 99 0 ENST00000264852.4:c.1966G>A p.Asp656Asn p.D656N ENST00000264852 NM_017699.2 656 Gat/Aat 0 +SLC10A2 UCSF GRCh37 13 103698539 103698539 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 48 6 108 0 ENST00000245312.3:c.991G>A p.Glu331Lys p.E331K ENST00000245312 NM_000452.2 331 Gag/Aag 0 +SLC10A4 UCSF GRCh37 4 48490831 48490831 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 79 20 88 0 ENST00000273861.4:c.1189G>A p.Asp397Asn p.D397N ENST00000273861 NM_152679.3 397 Gat/Aat 0 +SLC12A1 UCSF GRCh37 15 48539196 48539196 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0029 P21_Rec Untested WXS Illumina HiSeq 310 199 501 0 ENST00000396577.3:c.1543G>A p.Ala515Thr p.A515T ENST00000396577 NM_001184832.1 515 Gca/Aca 0 +SLC12A6 UCSF GRCh37 15 34533453 34533453 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 10 40 0 ENST00000354181.3:c.2248C>A p.Pro750Thr p.P750T ENST00000354181 750 Cca/Aca 0 +SLC17A2 UCSF GRCh37 6 25917232 25917232 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 189 36 141 0 ENST00000360488.3:c.733G>A p.Glu245Lys p.E245K ENST00000360488 NM_005835.2 245 Gaa/Aaa 0 +SLC24A5 UCSF GRCh37 15 48428997 48428997 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 136 37 146 0 ENST00000341459.3:c.708C>T p.Ala236= p.A236= ENST00000341459 NM_205850.2 236 gcC/gcT 0 +SLC25A14 UCSF GRCh37 X 129506898 129506898 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 126 100 210 0 ENST00000218197.5:c.952G>A p.Glu318Lys p.E318K ENST00000218197 NM_022810.1 318 Gag/Aag 0 +SLC25A25 UCSF GRCh37 9 130869597 130869597 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 147 33 211 0 ENST00000373068.2:c.1386G>A p.Arg462= p.R462= ENST00000373068 NM_001006641.3 462 cgG/cgA 0 +SLC26A8 UCSF GRCh37 6 35927270 35927270 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 269 54 195 0 ENST00000490799.1:c.1830C>T p.Phe610= p.F610= ENST00000490799 NM_052961.3 610 ttC/ttT 0 +SLC27A3 UCSF GRCh37 1 153750305 153750305 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 106 23 175 0 ENST00000368661.3:c.1246G>A p.Val416Met p.V416M ENST00000368661 NM_024330.1 416 Gtg/Atg 0 +SLC28A1 UCSF GRCh37 15 85438637 85438637 + intron_variant Intron SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 62 28 86 0 ENST00000394573.1:c.461+283C>T *154* ENST00000394573 NM_004213.3 0 +SLC29A4 UCSF GRCh37 7 5340179 5340179 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 162 61 343 0 ENST00000396872.3:c.1336C>T p.Pro446Ser p.P446S ENST00000396872 446 Ccc/Tcc 0 +SLC30A1 UCSF GRCh37 1 211749269 211749269 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 178 48 241 1 ENST00000367001.4:c.985C>T p.Leu329Phe p.L329F ENST00000367001 NM_021194.2 329 Ctt/Ttt 0 +SLC30A6 UCSF GRCh37 2 32445766 32445766 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 68 42 167 0 ENST00000379343.2:c.1490G>A p.Gly497Glu p.G497E ENST00000379343 NM_001193513.1 497 gGa/gAa 0 +SLC35G1 UCSF GRCh37 10 95661083 95661083 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 92 18 144 0 ENST00000427197.1:c.934G>A p.Gly312Arg p.G312R ENST00000427197 NM_001134658.1 312 Ggg/Agg 0 +SLC41A2 UCSF GRCh37 12 105199074 105199074 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 259 30 390 1 ENST00000258538.3:c.1578C>T p.His526= p.H526= ENST00000258538 NM_032148.3 526 caC/caT 0 +SLC4A4 UCSF GRCh37 4 72222843 72222843 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 81 54 244 0 ENST00000425175.1:c.669C>T p.Ser223= p.S223= ENST00000425175 NM_001134742.1 223 tcC/tcT 0 +SLC5A6 UCSF GRCh37 2 27423865 27423865 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 62 13 112 0 ENST00000310574.3:c.1764+1G>A p.X588_splice ENST00000310574 NM_021095.2 0 +SLC6A11 UCSF GRCh37 3 10970906 10970906 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 261 43 322 0 ENST00000254488.2:c.1252C>T p.Leu418= p.L418= ENST00000254488 NM_014229.1 418 Ctg/Ttg 0 +SLC6A17 UCSF GRCh37 1 110741056 110741056 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 93 34 134 0 ENST00000331565.4:c.2174C>T p.Ser725Leu p.S725L ENST00000331565 NM_001010898.2 725 tCg/tTg 0 +SLC7A5 UCSF GRCh37 16 87874719 87874719 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 28 154 0 ENST00000261622.4:c.707C>T p.Thr236Ile p.T236I ENST00000261622 NM_003486.5 236 aCc/aTc 0 +SLC9A1 UCSF GRCh37 1 27426843 27426843 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 26 137 0 ENST00000263980.3:c.2403C>T p.His801= p.H801= ENST00000263980 NM_003047.4 801 caC/caT 0 +SLCO1B1 UCSF GRCh37 12 21350030 21350030 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 376 57 275 1 ENST00000256958.2:c.878C>T p.Ser293Leu p.S293L ENST00000256958 NM_006446.4 293 tCa/tTa 0 +SLCO1B7 UCSF GRCh37 12 21201727 21201727 + missense_variant Missense_Mutation SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 178 26 108 0 ENST00000421593.2:c.1076G>T p.Gly359Val p.G359V ENST00000421593 NM_001009562.4 359 gGa/gTa 0 +SLITRK2 UCSF GRCh37 X 144905522 144905522 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 66 42 138 0 ENST00000370490.1:c.1579C>T p.Gln527Ter p.Q527* ENST00000370490 527 Cag/Tag 0 +SMC2 UCSF GRCh37 9 106880459 106880459 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 112 18 133 0 ENST00000286398.7:c.1799C>T p.Pro600Leu p.P600L ENST00000286398 NM_006444.2 600 cCt/cTt 0 +SMG7 UCSF GRCh37 1 183514090 183514090 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 222 36 262 0 ENST00000507469.1:c.1875C>T p.Ile625= p.I625= ENST00000507469 NM_201569.2 625 atC/atT 0 +SMG9 UCSF GRCh37 19 44251951 44251951 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 55 10 53 0 ENST00000270066.6:c.324G>A p.Lys108= p.K108= ENST00000270066 NM_019108.2 108 aaG/aaA 0 +SMOC1 UCSF GRCh37 14 70418989 70418989 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 33 226 0 ENST00000361956.3:c.234C>T p.Thr78= p.T78= ENST00000361956 78 acC/acT 0 +SMOX UCSF GRCh37 20 4155907 4155907 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 102 36 162 0 ENST00000305958.4:c.205C>T p.Leu69Phe p.L69F ENST00000305958 NM_175839.2 69 Ctt/Ttt 0 +SNF8 UCSF GRCh37 17 47010644 47010644 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 125 32 169 0 ENST00000502492.1:c.487G>A p.Val163Met p.V163M ENST00000502492 163 Gtg/Atg 0 +SNIP1 UCSF GRCh37 1 38005897 38005897 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 47 214 0 ENST00000296215.6:c.787C>T p.Pro263Ser p.P263S ENST00000296215 NM_024700.3 263 Cca/Tca 0 +SNRPD2 UCSF GRCh37 19 46191721 46191721 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 45 217 0 ENST00000342669.3:c.106G>A p.Val36Ile p.V36I ENST00000342669 NM_004597.5 36 Gtc/Atc 0 +SNTG1 UCSF GRCh37 8 51362269 51362269 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 35 16 44 0 ENST00000522124.1:c.261C>T p.Ile87= p.I87= ENST00000522124 NM_018967.2 87 atC/atT 0 +SNUPN UCSF GRCh37 15 75890747 75890747 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 152 44 193 0 ENST00000564644.1:c.1035G>A p.Lys345= p.K345= ENST00000564644 345 aaG/aaA 0 +SORBS3 UCSF GRCh37 8 22423953 22423953 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 170 19 209 0 ENST00000240123.7:c.1046C>T p.Pro349Leu p.P349L ENST00000240123 NM_005775.4 349 cCc/cTc 0 +SOS2 UCSF GRCh37 14 50585328 50585328 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 81 27 144 0 ENST00000216373.5:c.3733G>A p.Asp1245Asn p.D1245N ENST00000216373 NM_006939.2 1245 Gat/Aat 0 +SPAG11B UCSF GRCh37 8 7320250 7320250 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 173 32 503 0 ENST00000398462.2:c.193C>T p.Pro65Ser p.P65S ENST00000398462 NM_058201.2 65 Ccg/Tcg 0 +SPAG17 UCSF GRCh37 1 118565973 118565973 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 21 111 0 ENST00000336338.5:c.4023G>A p.Gln1341= p.Q1341= ENST00000336338 NM_206996.2 1341 caG/caA 0 +SPAG9 UCSF GRCh37 17 49083481 49083481 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 238 60 306 0 ENST00000262013.7:c.1389G>A p.Glu463= p.E463= ENST00000262013 NM_001130528.2 463 gaG/gaA 0 +SPEN UCSF GRCh37 1 16259115 16259115 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 176 57 303 0 ENST00000375759.3:c.6380C>T p.Pro2127Leu p.P2127L ENST00000375759 NM_015001.2 2127 cCc/cTc 0 +SPON1 UCSF GRCh37 11 14287095 14287095 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 60 32 148 0 ENST00000310358.7:n.2821C>T *941* ENST00000310358 0 +SPRED2 UCSF GRCh37 2 65571911 65571911 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 35 12 95 0 ENST00000356388.4:c.146C>T p.Pro49Leu p.P49L ENST00000356388 NM_181784.2 49 cCc/cTc 0 +SRRM3 UCSF GRCh37 7 75915110 75915110 + 3_prime_UTR_variant 3'UTR SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 9 6 16 0 ENST00000326382.8:c.*117C>T *39* ENST00000326382 NM_001110199.1 0 +SRSF4 UCSF GRCh37 1 29475117 29475117 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 341 47 508 0 ENST00000373795.4:c.1290G>A p.Glu430= p.E430= ENST00000373795 NM_005626.4 430 gaG/gaA 0 +SRSF7 UCSF GRCh37 2 38977222 38977222 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 121 41 188 0 ENST00000313117.6:c.143G>A p.Gly48Glu p.G48E ENST00000313117 NM_001195446.1 48 gGa/gAa 0 +SSC5D UCSF GRCh37 19 56009384 56009384 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 52 13 55 0 ENST00000389623.6:c.1525G>A p.Gly509Ser p.G509S ENST00000389623 NM_001144950.1 509 Ggc/Agc 0 +SSPN UCSF GRCh37 12 26377228 26377228 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 348 65 304 0 ENST00000242729.2:c.282C>T p.Val94= p.V94= ENST00000242729 NM_005086.4 94 gtC/gtT 0 +SSPO UCSF GRCh37 7 149489775 149489775 + non_coding_transcript_exon_variant RNA SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 43 12 100 0 ENST00000378016.2:n.5831G>T *1944* ENST00000378016 0 +STAM UCSF GRCh37 10 17750927 17750927 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 42 160 0 ENST00000377524.3:c.1362G>A p.Gln454= p.Q454= ENST00000377524 NM_003473.3 454 caG/caA 0 +STBD1 UCSF GRCh37 4 77228007 77228007 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 11 6 30 0 ENST00000237642.6:c.85G>A p.Asp29Asn p.D29N ENST00000237642 NM_003943.4 29 Gac/Aac 0 +STK4 UCSF GRCh37 20 43629817 43629817 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 85 19 112 0 ENST00000372806.3:c.970G>A p.Glu324Lys p.E324K ENST00000372806 NM_006282.2 324 Gaa/Aaa 0 +STRA6 UCSF GRCh37 15 74473662 74473662 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 37 6 46 0 ENST00000563965.1:c.1775C>T p.Pro592Leu p.P592L ENST00000563965 592 cCa/cTa 0 +SUFU UCSF GRCh37 10 104309744 104309744 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 133 44 256 0 ENST00000369902.3:c.335G>A p.Gly112Glu p.G112E ENST00000369902 NM_016169.3 112 gGa/gAa 0 +SUMF1 UCSF GRCh37 3 4452646 4452646 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 150 29 175 0 ENST00000272902.5:c.857C>T p.Pro286Leu p.P286L ENST00000272902 NM_182760.3 286 cCc/cTc 0 +SUPV3L1 UCSF GRCh37 10 70949130 70949130 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 117 14 143 0 ENST00000359655.4:c.680G>A p.Gly227Glu p.G227E ENST00000359655 NM_003171.3 227 gGa/gAa 0 +SVEP1 UCSF GRCh37 9 113151837 113151837 + missense_variant Missense_Mutation SNP T T C 1000g2011may_all_0.0014 P21_Rec Untested WXS Illumina HiSeq 133 107 239 0 ENST00000401783.2:c.9853A>G p.Arg3285Gly p.R3285G ENST00000401783 NM_153366.3 3285 Aga/Gga 0 +SVIL UCSF GRCh37 10 29822130 29822130 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 30 189 0 ENST00000375398.2:c.1166C>T p.Ser389Phe p.S389F ENST00000375398 389 tCt/tTt 0 +SYCE1 UCSF GRCh37 10 135369192 135369192 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 21 17 74 0 ENST00000343131.5:c.739C>T p.His247Tyr p.H247Y ENST00000343131 NM_001143764.1 247 Cac/Tac 0 +SYMPK UCSF GRCh37 19 46352083 46352083 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 108 66 179 0 ENST00000245934.7:c.351C>T p.Leu117= p.L117= ENST00000245934 NM_004819.2 117 ctC/ctT 0 +SYNJ1 UCSF GRCh37 21 34067381 34067381 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 272 35 211 0 ENST00000433931.2:c.808G>A p.Val270Ile p.V270I ENST00000433931 NM_003895.3 270 Gta/Ata 0 +SYNPO UCSF GRCh37 5 150028638 150028638 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 16 92 0 ENST00000394243.1:c.1533G>A p.Glu511= p.E511= ENST00000394243 NM_001166208.1 511 gaG/gaA 0 +TAF1 UCSF GRCh37 X 70618489 70618489 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 38 21 78 0 ENST00000276072.3:c.3748G>A p.Glu1250Lys p.E1250K ENST00000276072 1250 Gag/Aag 0 +TAF1L UCSF GRCh37 9 32633675 32633675 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 200 54 240 0 ENST00000242310.4:c.1903C>T p.His635Tyr p.H635Y ENST00000242310 NM_153809.2 635 Cat/Tat 0 +TAP1 UCSF GRCh37 6 32816791 32816791 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 43 8 30 0 ENST00000354258.4:c.1533G>A p.Gln511= p.Q511= ENST00000354258 NM_000593.5 511 caG/caA 0 +TARBP1 UCSF GRCh37 1 234534285 234534285 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 66 18 75 0 ENST00000040877.1:c.4086C>T p.Ile1362= p.I1362= ENST00000040877 NM_005646.3 1362 atC/atT 0 +TAS2R30 UCSF GRCh37 12 11286352 11286352 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 525 110 535 0 ENST00000539585.1:c.492G>A p.Trp164Ter p.W164* ENST00000539585 NM_001097643.1 164 tgG/tgA 0 +TBC1D10A UCSF GRCh37 22 30722783 30722783 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 27 10 36 0 ENST00000403477.3:c.88C>T p.Pro30Ser p.P30S ENST00000403477 NM_001204240.1 30 Ccc/Tcc 0 +TBCB UCSF GRCh37 19 36611642 36611642 + missense_variant Missense_Mutation SNP G G C NOVEL P21_Rec Untested WXS Illumina HiSeq 53 11 68 0 ENST00000221855.3:c.289G>C p.Glu97Gln p.E97Q ENST00000221855 NM_001281.2 97 Gag/Cag 0 +TBP UCSF GRCh37 6 170876034 170876034 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 18 9 68 0 ENST00000392092.2:c.614G>A p.Arg205Lys p.R205K ENST00000392092 NM_003194.4 205 aGa/aAa 0 +TBX10 UCSF GRCh37 11 67399796 67399796 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 100 27 136 0 ENST00000335385.3:c.861G>A p.Arg287= p.R287= ENST00000335385 NM_005995.4 287 agG/agA 0 +TCEB3 UCSF GRCh37 1 24078002 24078002 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.00094 P21_Rec Untested WXS Illumina HiSeq 137 34 206 0 ENST00000418390.2:c.985G>A p.Asp329Asn p.D329N ENST00000418390 NM_003198.2 329 Gac/Aac 0 +TCOF1 UCSF GRCh37 5 149756077 149756077 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 24 8 52 0 ENST00000504761.2:c.2234G>A p.Gly745Glu p.G745E ENST00000504761 745 gGg/gAg 0 +TDP1 UCSF GRCh37 14 90458304 90458304 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 52 14 89 0 ENST00000335725.4:c.1410G>A p.Gln470= p.Q470= ENST00000335725 NM_018319.3 470 caG/caA 0 +TDRD1 UCSF GRCh37 10 115986970 115986970 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 79 28 185 0 ENST00000251864.2:c.3315G>A p.Glu1105= p.E1105= ENST00000251864 NM_198795.1 1105 gaG/gaA 0 +TET1 UCSF GRCh37 10 70427014 70427014 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 45 5 53 0 ENST00000373644.4:c.4673+1G>A p.X1558_splice ENST00000373644 NM_030625.2 0 +TEX2 UCSF GRCh37 17 62290570 62290570 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 37 140 0 ENST00000258991.3:c.1008G>A p.Gly336= p.G336= ENST00000258991 NM_001288732.1 336 ggG/ggA 0 +TFEB UCSF GRCh37 6 41658886 41658886 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 26 6 17 0 ENST00000230323.4:c.66G>A p.Arg22= p.R22= ENST00000230323 NM_007162.2 22 cgG/cgA 0 +TFG UCSF GRCh37 3 100438827 100438827 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 59 13 80 0 ENST00000240851.4:c.193C>T p.Leu65Phe p.L65F ENST00000240851 NM_001195478.1 65 Ctt/Ttt 0 +THAP6 UCSF GRCh37 4 76442089 76442089 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 38 38 121 0 ENST00000311638.3:c.188C>T p.Ser63Leu p.S63L ENST00000311638 NM_144721.4 63 tCg/tTg 0 +THBS1 UCSF GRCh37 15 39882761 39882761 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 92 26 107 0 ENST00000260356.5:c.2190C>T p.Asp730= p.D730= ENST00000260356 NM_003246.2 730 gaC/gaT 0 +THRA UCSF GRCh37 17 38242972 38242972 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 94 25 117 0 ENST00000264637.4:c.589G>A p.Gly197Ser p.G197S ENST00000264637 NM_003250.5 197 Ggc/Agc 0 +THSD4 UCSF GRCh37 15 72030269 72030269 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 132 27 229 0 ENST00000355327.3:c.1829C>T p.Pro610Leu p.P610L ENST00000355327 610 cCg/cTg 0 +THSD7A UCSF GRCh37 7 11632897 11632897 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 236 51 411 0 ENST00000423059.4:c.1255G>A p.Val419Ile p.V419I ENST00000423059 NM_015204.2 419 Gtt/Att 0 +THSD7A UCSF GRCh37 7 11632919 11632919 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 237 36 422 0 ENST00000423059.4:c.1233C>T p.Pro411= p.P411= ENST00000423059 NM_015204.2 411 ccC/ccT 0 +THUMPD2 UCSF GRCh37 2 39982434 39982434 + splice_donor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 38 21 57 0 ENST00000505747.1:c.1078+1G>A p.X360_splice ENST00000505747 NM_025264.4 0 +TIGD3 UCSF GRCh37 11 65124305 65124305 + missense_variant Missense_Mutation SNP C C A NOVEL P21_Rec Untested WXS Illumina HiSeq 99 22 129 0 ENST00000309880.5:c.1026C>A p.His342Gln p.H342Q ENST00000309880 NM_145719.2 342 caC/caA 0 +TIMP3 UCSF GRCh37 22 33253331 33253331 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 17 163 0 ENST00000266085.6:c.300C>T p.Tyr100= p.Y100= ENST00000266085 NM_000362.4 100 taC/taT 0 +TLE2 UCSF GRCh37 19 3011090 3011090 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 13 6 34 0 ENST00000262953.6:c.942C>T p.Thr314= p.T314= ENST00000262953 NM_003260.4 314 acC/acT 0 +TLR9 UCSF GRCh37 3 52255337 52255337 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 116 26 172 0 ENST00000360658.2:c.2995C>T p.Pro999Ser p.P999S ENST00000360658 NM_017442.3 999 Ccc/Tcc 0 +TMBIM6 UCSF GRCh37 12 50146858 50146858 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 61 25 144 0 ENST00000423828.1:c.333C>T p.Phe111= p.F111= ENST00000423828 NM_001098576.1 111 ttC/ttT 0 +TMC3 UCSF GRCh37 15 81627309 81627309 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 162 42 253 0 ENST00000359440.5:c.2211C>T p.Ile737= p.I737= ENST00000359440 NM_001080532.1 737 atC/atT 0 +TMC6 UCSF GRCh37 17 76122611 76122611 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 37 11 66 0 ENST00000590602.1:c.175G>A p.Val59Met p.V59M ENST00000590602 59 Gtg/Atg 0 +TMCO4 UCSF GRCh37 1 20066374 20066374 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 81 35 119 0 ENST00000294543.6:c.1122C>T p.Leu374= p.L374= ENST00000294543 NM_181719.4 374 ctC/ctT 0 +TMEM106B UCSF GRCh37 7 12258127 12258127 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 33 14 43 0 ENST00000396667.3:c.261G>A p.Gln87= p.Q87= ENST00000396667 NM_018374.3 87 caG/caA 0 +TMEM237 UCSF GRCh37 2 202503751 202503751 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 72 18 116 0 ENST00000409883.2:c.97C>T p.Arg33Cys p.R33C ENST00000409883 NM_001044385.2 33 Cgt/Tgt 0 +TMEM74 UCSF GRCh37 8 109796670 109796670 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 123 19 122 0 ENST00000297459.3:c.658G>A p.Glu220Lys p.E220K ENST00000297459 NM_153015.1 220 Gag/Aag 0 +TMPRSS15 UCSF GRCh37 21 19685352 19685352 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 163 32 163 0 ENST00000284885.3:c.2075G>A p.Arg692Gln p.R692Q ENST00000284885 NM_002772.2 692 cGg/cAg 0 +TMPRSS15 UCSF GRCh37 21 19687538 19687538 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 108 26 117 0 ENST00000284885.3:c.1957G>A p.Gly653Arg p.G653R ENST00000284885 NM_002772.2 653 Gga/Aga 0 +TMTC2 UCSF GRCh37 12 83290098 83290098 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 240 77 402 0 ENST00000321196.3:c.1156C>T p.Gln386Ter p.Q386* ENST00000321196 NM_152588.1 386 Cag/Tag 0 +TMTC4 UCSF GRCh37 13 101288914 101288914 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 56 29 230 0 ENST00000342624.5:c.1074G>A p.Trp358Ter p.W358* ENST00000342624 NM_032813.2 358 tgG/tgA 0 +TNFRSF10A UCSF GRCh37 8 23082424 23082424 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 19 5 23 0 ENST00000221132.3:c.151G>A p.Gly51Ser p.G51S ENST00000221132 NM_003844.3 51 Ggc/Agc 0 +TNFRSF1A UCSF GRCh37 12 6439070 6439070 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 22 8 21 0 ENST00000162749.2:c.931C>T p.Arg311Cys p.R311C ENST00000162749 NM_001065.3 311 Cgc/Tgc 0 +TNFRSF8 UCSF GRCh37 1 12198444 12198444 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 31 4 58 0 ENST00000263932.2:c.1494G>A p.Arg498= p.R498= ENST00000263932 NM_001243.3 498 agG/agA 0 +TNKS1BP1 UCSF GRCh37 11 57088121 57088121 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 30 6 43 0 ENST00000532437.1:c.160C>T p.Pro54Ser p.P54S ENST00000532437 54 Cct/Tct 0 +TNPO3 UCSF GRCh37 7 128610265 128610265 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 165 68 295 0 ENST00000265388.5:c.2535C>T p.Leu845= p.L845= ENST00000265388 845 ctC/ctT 0 +TNRC6A UCSF GRCh37 16 24826609 24826609 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 67 21 91 0 ENST00000395799.3:c.4814G>A p.Ser1605Asn p.S1605N ENST00000395799 NM_014494.2 1605 aGt/aAt 0 +TNRC6B UCSF GRCh37 22 40681770 40681770 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 339 73 405 0 ENST00000454349.2:c.3704C>T p.Pro1235Leu p.P1235L ENST00000454349 NM_001162501.1 1235 cCc/cTc 0 +TOM1L2 UCSF GRCh37 17 17786035 17786035 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 116 28 153 0 ENST00000379504.3:c.644C>T p.Thr215Ile p.T215I ENST00000379504 NM_001082968.1 215 aCa/aTa 0 +TOPBP1 UCSF GRCh37 3 133331320 133331320 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 164 37 206 0 ENST00000260810.5:c.3948G>A p.Glu1316= p.E1316= ENST00000260810 NM_007027.3 1316 gaG/gaA 0 +TOPBP1 UCSF GRCh37 3 133375522 133375522 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 237 59 234 0 ENST00000260810.5:c.543G>A p.Glu181= p.E181= ENST00000260810 NM_007027.3 181 gaG/gaA 0 +TOR2A UCSF GRCh37 9 130496642 130496642 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 62 19 70 0 ENST00000373284.5:c.353C>T p.Pro118Leu p.P118L ENST00000373284 NM_001085347.2 118 cCc/cTc 0 +TP53 UCSF GRCh37 17 7578388 7578388 + missense_variant Missense_Mutation SNP C C G NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 53 43 127 0 ENST00000269305.4:c.542G>C p.Arg181Pro p.R181P ENST00000269305 NM_001126112.2 181 cGc/cCc 0 +TP53 UCSF GRCh37 17 7577121 7577121 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 58 44 129 0 ENST00000269305.4:c.817C>T p.Arg273Cys p.R273C ENST00000269305 NM_001126112.2 273 Cgt/Tgt 0 +TP53 UCSF GRCh37 17 7579434 7579434 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec somatic WXS Sanger Illumina HiSeq 152 59 241 0 ENST00000269305.4:c.253C>T p.Pro85Ser p.P85S ENST00000269305 NM_001126112.2 85 Cct/Tct 0 +TPM4 UCSF GRCh37 19 16186900 16186900 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 24 3 31 0 ENST00000538887.1:c.158C>T p.Thr53Ile p.T53I ENST00000538887 53 aCa/aTa 0 +TPO UCSF GRCh37 2 1507752 1507752 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 68 25 136 0 ENST00000345913.4:c.2419C>T p.Pro807Ser p.P807S ENST00000345913 NM_000547.5 807 Ccc/Tcc 0 +TPTE2 UCSF GRCh37 13 20056662 20056662 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 63 26 189 0 ENST00000400230.2:c.145G>A p.Glu49Lys p.E49K ENST00000400230 49 Gaa/Aaa 0 +TRHDE UCSF GRCh37 12 72771831 72771831 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 73 15 75 0 ENST00000261180.4:c.1110C>T p.Leu370= p.L370= ENST00000261180 NM_013381.2 370 ctC/ctT 0 +TRIM14 UCSF GRCh37 9 100850237 100850237 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 13 4 17 0 ENST00000341469.2:c.844C>T p.Leu282= p.L282= ENST00000341469 NM_014788.2 282 Ctg/Ttg 0 +TRIM28 UCSF GRCh37 19 59059517 59059517 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 316 77 457 0 ENST00000253024.5:c.1071C>T p.Asn357= p.N357= ENST00000253024 NM_005762.2 357 aaC/aaT 0 +TRIM44 UCSF GRCh37 11 35706878 35706878 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 29 23 111 0 ENST00000299413.5:c.741C>T p.Asp247= p.D247= ENST00000299413 NM_017583.4 247 gaC/gaT 0 +TRIOBP UCSF GRCh37 22 38151613 38151613 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 107 30 156 0 ENST00000406386.3:c.5634G>A p.Trp1878Ter p.W1878* ENST00000406386 NM_001039141.2 1878 tgG/tgA 0 +TRMT12 UCSF GRCh37 8 125464397 125464397 + missense_variant Missense_Mutation SNP T T C NOVEL P21_Rec Untested WXS Illumina HiSeq 175 27 153 0 ENST00000328599.3:c.1229T>C p.Val410Ala p.V410A ENST00000328599 NM_017956.3 410 gTg/gCg 0 +TRO UCSF GRCh37 X 54949475 54949475 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 13 70 0 ENST00000173898.7:c.510G>A p.Leu170= p.L170= ENST00000173898 NM_001039705.2 170 ttG/ttA 0 +TRPS1 UCSF GRCh37 8 116426892 116426892 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 315 48 228 0 ENST00000395715.3:c.3244G>A p.Glu1082Lys p.E1082K ENST00000395715 NM_014112.2 1082 Gaa/Aaa 0 +TSFM UCSF GRCh37 12 58190181 58190181 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 41 10 60 0 ENST00000323833.8:c.856C>T p.Pro286Ser p.P286S ENST00000323833 NM_001172696.1 286 Ccc/Tcc 0 +TSHZ3 UCSF GRCh37 19 31768293 31768293 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 157 31 216 0 ENST00000240587.4:c.2406C>T p.Ser802= p.S802= ENST00000240587 NM_020856.2 802 tcC/tcT 0 +TSPAN3 UCSF GRCh37 15 77339196 77339196 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 17 4 35 0 ENST00000267970.4:c.743C>T p.Thr248Ile p.T248I ENST00000267970 NM_001168412.1 248 aCt/aTt 0 +TST UCSF GRCh37 22 37414267 37414267 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 53 13 69 0 ENST00000403892.3:c.507G>A p.Leu169= p.L169= ENST00000403892 NM_001270483.1 169 ctG/ctA 0 +TTC17 UCSF GRCh37 11 43469637 43469637 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 50 40 158 0 ENST00000039989.4:c.2751G>A p.Val917= p.V917= ENST00000039989 NM_018259.5 917 gtG/gtA 0 +TTC21B UCSF GRCh37 2 166756331 166756331 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 50 23 91 0 ENST00000243344.7:c.2817G>A p.Arg939= p.R939= ENST00000243344 NM_024753.4 939 cgG/cgA 0 +TTC21B UCSF GRCh37 2 166797655 166797655 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 81 25 128 0 ENST00000243344.7:c.592C>T p.Leu198= p.L198= ENST00000243344 NM_024753.4 198 Ctg/Ttg 0 +TTC4 UCSF GRCh37 1 55207137 55207137 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 161 28 216 0 ENST00000371281.3:c.1115C>T p.Pro372Leu p.P372L ENST00000371281 NM_004623.4 372 cCt/cTt 0 +TTK UCSF GRCh37 6 80736183 80736183 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 80 39 229 0 ENST00000369798.2:c.1346C>T p.Ser449Phe p.S449F ENST00000369798 NM_003318.4 449 tCt/tTt 0 +TTN UCSF GRCh37 2 179560080 179560080 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 68 25 127 0 ENST00000589042.1:c.31265C>T p.Pro10422Leu p.P10422L ENST00000589042 NM_001267550.1 10422 cCt/cTt 0 +TTN UCSF GRCh37 2 179427207 179427207 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 223 75 385 0 ENST00000589042.1:c.83652G>A p.Trp27884Ter p.W27884* ENST00000589042 NM_001267550.1 27884 tgG/tgA 0 +TUBAL3 UCSF GRCh37 10 5436278 5436278 + synonymous_variant Silent SNP G G T NOVEL P21_Rec Untested WXS Illumina HiSeq 115 57 142 0 ENST00000380419.3:c.543C>A p.Ala181= p.A181= ENST00000380419 NM_024803.2 181 gcC/gcA 0 +TUFT1 UCSF GRCh37 1 151546806 151546806 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 21 93 0 ENST00000368849.3:c.655G>A p.Glu219Lys p.E219K ENST00000368849 NM_020127.2 219 Gag/Aag 0 +TXNDC12 UCSF GRCh37 1 52489209 52489209 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 107 30 144 0 ENST00000371626.4:c.393G>A p.Glu131= p.E131= ENST00000371626 NM_015913.3 131 gaG/gaA 0 +TXNDC16 UCSF GRCh37 14 52899137 52899137 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 103 28 155 1 ENST00000281741.4:c.2363G>A p.Arg788Lys p.R788K ENST00000281741 NM_020784.2 788 aGa/aAa 0 +TXNDC5 UCSF GRCh37 6 7884664 7884664 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 174 38 213 0 ENST00000379757.4:c.1104C>T p.Phe368= p.F368= ENST00000379757 NM_030810.3 368 ttC/ttT 0 +TYMP UCSF GRCh37 22 50967706 50967706 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 74 18 102 0 ENST00000395681.1:c.276C>T p.Thr92= p.T92= ENST00000395681 92 acC/acT 0 +TYW1B UCSF GRCh37 7 72178679 72178679 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 121 41 330 0 ENST00000343721.5:c.148C>T p.Pro50Ser p.P50S ENST00000343721 50 Cca/Tca 0 +TYW5 UCSF GRCh37 2 200798002 200798002 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 79 29 132 0 ENST00000354611.4:c.736G>A p.Val246Met p.V246M ENST00000354611 NM_001039693.2 246 Gtg/Atg 0 +U2AF2 UCSF GRCh37 19 56171880 56171880 + splice_acceptor_variant Splice_Site SNP A A C NOVEL P21_Rec Untested WXS Illumina HiSeq 18 6 28 1 ENST00000308924.4:c.231-2A>C p.X77_splice ENST00000308924 0 +U2SURP UCSF GRCh37 3 142735817 142735817 + splice_region_variant,synonymous_variant Splice_Region SNP T T A NOVEL P21_Rec Untested WXS Illumina HiSeq 158 26 167 0 ENST00000473835.2:c.570T>A p.Pro190= p.P190= ENST00000473835 NM_001080415.1 190 ccT/ccA 0 +UBE4B UCSF GRCh37 1 10221321 10221321 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 101 27 141 0 ENST00000343090.6:c.3175G>A p.Glu1059Lys p.E1059K ENST00000343090 NM_001105562.2 1059 Gaa/Aaa 0 +UBFD1 UCSF GRCh37 16 23570865 23570865 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 97 24 134 0 ENST00000395878.3:c.432G>A p.Val144= p.V144= ENST00000395878 NM_019116.2 144 gtG/gtA 0 +UBOX5 UCSF GRCh37 20 3102943 3102943 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 16 133 0 ENST00000217173.2:c.342G>A p.Ala114= p.A114= ENST00000217173 NM_001267584.1 114 gcG/gcA 0 +UGDH UCSF GRCh37 4 39511429 39511429 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.003,1000g2011may_all_0.0022 P21_Rec Untested WXS Illumina HiSeq 92 15 114 1 ENST00000316423.6:c.762G>A p.Ala254= p.A254= ENST00000316423 NM_001184701.1 254 gcG/gcA 0 +UGP2 UCSF GRCh37 2 64109776 64109776 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 99 41 173 1 ENST00000337130.5:c.432G>A p.Gln144= p.Q144= ENST00000337130 NM_006759.3 144 caG/caA 0 +UMODL1 UCSF GRCh37 21 43543178 43543178 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 113 15 151 0 ENST00000408989.2:c.3449C>T p.Pro1150Leu p.P1150L ENST00000408989 NM_173568.3 1150 cCc/cTc 0 +UNC13B UCSF GRCh37 9 35385781 35385781 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 151 45 184 0 ENST00000378495.3:c.2689C>T p.Leu897= p.L897= ENST00000378495 NM_006377.3 897 Ctg/Ttg 0 +UNC79 UCSF GRCh37 14 94063753 94063753 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 135 29 241 0 ENST00000256339.4:c.2708C>T p.Thr903Ile p.T903I ENST00000256339 NM_020818.3 903 aCc/aTc 0 +UNC80 UCSF GRCh37 2 210840926 210840926 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 30 21 92 0 ENST00000439458.1:c.8473C>T p.Leu2825= p.L2825= ENST00000439458 NM_032504.1 2825 Ctg/Ttg 0 +UNKL UCSF GRCh37 16 1416349 1416349 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 10 5 29 0 ENST00000389221.4:c.1935G>A p.Arg645= p.R645= ENST00000389221 NM_001193388.3 645 cgG/cgA 0 +URM1 UCSF GRCh37 9 131140376 131140376 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 305 87 432 0 ENST00000452446.1:c.97G>A p.Glu33Lys p.E33K ENST00000452446 NM_001135947.2 33 Gag/Aag 0 +UROC1 UCSF GRCh37 3 126211359 126211359 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 39 6 60 0 ENST00000383579.3:c.1690G>A p.Val564Met p.V564M ENST00000383579 NM_001165974.1 564 Gtg/Atg 0 +USP15 UCSF GRCh37 12 62688014 62688014 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 77 16 87 0 ENST00000280377.5:c.144C>T p.Asp48= p.D48= ENST00000280377 NM_001252078.1 48 gaC/gaT 0 +USP24 UCSF GRCh37 1 55591349 55591349 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 112 36 179 0 ENST00000294383.6:c.3718C>T p.Leu1240= p.L1240= ENST00000294383 NM_015306.2 1240 Cta/Tta 0 +USP4 UCSF GRCh37 3 49316274 49316274 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 228 59 342 1 ENST00000265560.4:c.2706G>A p.Val902= p.V902= ENST00000265560 NM_003363.3 902 gtG/gtA 0 +VARS UCSF GRCh37 6 31759704 31759704 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 53 6 49 0 ENST00000375663.3:c.916G>A p.Glu306Lys p.E306K ENST00000375663 NM_006295.2 306 Gag/Aag 0 +VARS UCSF GRCh37 6 31747218 31747218 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 74 9 39 0 ENST00000375663.3:c.3384C>T p.Thr1128= p.T1128= ENST00000375663 NM_006295.2 1128 acC/acT 0 +VPRBP UCSF GRCh37 3 51440745 51440745 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 294 90 442 0 ENST00000423656.1:c.3010C>T p.Leu1004= p.L1004= ENST00000423656 1004 Ctg/Ttg 0 +VPS13C UCSF GRCh37 15 62202505 62202505 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 44 8 57 0 ENST00000261517.5:c.8716-1G>A p.X2906_splice ENST00000261517 NM_020821.2 0 +VPS37C UCSF GRCh37 11 60900006 60900006 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 40 14 76 0 ENST00000301765.5:c.354G>A p.Met118Ile p.M118I ENST00000301765 NM_017966.4 118 atG/atA 0 +VPS41 UCSF GRCh37 7 38835080 38835080 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 87 28 196 0 ENST00000310301.4:c.702G>A p.Trp234Ter p.W234* ENST00000310301 NM_014396.3 234 tgG/tgA 0 +VWC2 UCSF GRCh37 7 49951759 49951759 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 66 11 130 0 ENST00000340652.4:c.956G>A p.Arg319Lys p.R319K ENST00000340652 NM_198570.3 319 aGa/aAa 0 +WAPAL UCSF GRCh37 10 88259980 88259980 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 200 66 406 0 ENST00000298767.5:c.1020G>A p.Gly340= p.G340= ENST00000298767 NM_015045.2 340 ggG/ggA 0 +WBP2NL UCSF GRCh37 22 42418293 42418293 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 34 150 0 ENST00000328823.9:c.447C>T p.Phe149= p.F149= ENST00000328823 NM_152613.2 149 ttC/ttT 0 +WDHD1 UCSF GRCh37 14 55408278 55408278 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 68 21 85 0 ENST00000360586.3:c.3320C>T p.Ser1107Phe p.S1107F ENST00000360586 NM_007086.3 1107 tCt/tTt 0 +WDR19 UCSF GRCh37 4 39206875 39206875 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 228 45 204 0 ENST00000399820.3:c.705C>T p.Val235= p.V235= ENST00000399820 NM_025132.3 235 gtC/gtT 0 +WDR33 UCSF GRCh37 2 128463960 128463960 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 161 55 310 0 ENST00000322313.4:c.3948G>A p.Gly1316= p.G1316= ENST00000322313 NM_018383.4 1316 ggG/ggA 0 +WDR34 UCSF GRCh37 9 131403107 131403107 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 79 22 124 0 ENST00000372715.2:c.298C>T p.Pro100Ser p.P100S ENST00000372715 NM_052844.3 100 Ccg/Tcg 0 +WDR35 UCSF GRCh37 2 20166556 20166556 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 61 22 118 0 ENST00000345530.3:c.1123G>A p.Gly375Ser p.G375S ENST00000345530 NM_001006657.1 375 Ggt/Agt 0 +WDR36 UCSF GRCh37 5 110445982 110445982 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 218 48 229 0 ENST00000506538.2:c.1589G>A p.Gly530Glu p.G530E ENST00000506538 NM_139281.2 530 gGa/gAa 0 +WDR60 UCSF GRCh37 7 158718922 158718922 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 123 42 235 0 ENST00000407559.3:c.2302G>A p.Val768Ile p.V768I ENST00000407559 NM_018051.4 768 Gta/Ata 0 +WDR7 UCSF GRCh37 18 54363620 54363620 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 102 25 187 0 ENST00000254442.3:c.1505G>A p.Gly502Glu p.G502E ENST00000254442 NM_015285.2 502 gGa/gAa 0 +WDR7 UCSF GRCh37 18 54385293 54385293 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 91 28 160 0 ENST00000254442.3:c.1677C>T p.His559= p.H559= ENST00000254442 NM_015285.2 559 caC/caT 0 +WNK2 UCSF GRCh37 9 96010058 96010058 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 14 6 26 0 ENST00000297954.4:c.1776G>A p.Pro592= p.P592= ENST00000297954 NM_001282394.1 592 ccG/ccA 0 +WNK2 UCSF GRCh37 9 96051290 96051290 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 28 7 40 0 ENST00000297954.4:c.4365G>A p.Gly1455= p.G1455= ENST00000297954 NM_001282394.1 1455 ggG/ggA 0 +WT1 UCSF GRCh37 11 32456391 32456391 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 13 4 26 0 ENST00000332351.3:c.501G>A p.Gln167= p.Q167= ENST00000332351 NM_024426.4 167 caG/caA 0 +XAB2 UCSF GRCh37 19 7687515 7687515 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 70 21 113 0 ENST00000358368.4:c.1404G>A p.Glu468= p.E468= ENST00000358368 NM_020196.2 468 gaG/gaA 0 +XAB2 UCSF GRCh37 19 7692635 7692635 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 159 31 186 0 ENST00000358368.4:c.303G>A p.Arg101= p.R101= ENST00000358368 NM_020196.2 101 agG/agA 0 +XIRP2 UCSF GRCh37 2 168106609 168106609 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 105 44 179 0 ENST00000409195.1:c.8707G>A p.Gly2903Ser p.G2903S ENST00000409195 NM_152381.5 2903 Ggc/Agc 0 +XKR6 UCSF GRCh37 8 11058163 11058163 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 17 9 51 0 ENST00000416569.2:c.686G>A p.Gly229Glu p.G229E ENST00000416569 NM_173683.3 229 gGg/gAg 0 +YAF2 UCSF GRCh37 12 42555550 42555550 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 49 6 98 0 ENST00000442791.3:c.242C>T p.Ser81Phe p.S81F ENST00000442791 NM_001190979.1 81 tCc/tTc 0 +YLPM1 UCSF GRCh37 14 75295966 75295966 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 252 53 423 0 ENST00000325680.7:c.6214G>A p.Ala2072Thr p.A2072T ENST00000325680 NM_019589.2 2072 Gcc/Acc 0 +YWHAZ UCSF GRCh37 8 101932975 101932975 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 117 15 112 0 ENST00000395957.2:c.684G>A p.Trp228Ter p.W228* ENST00000395957 228 tgG/tgA 0 +ZACN UCSF GRCh37 17 74078655 74078655 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 105 20 136 0 ENST00000334586.5:c.1160G>A p.Gly387Glu p.G387E ENST00000334586 NM_180990.3 387 gGa/gAa 0 +ZBTB9 UCSF GRCh37 6 33423368 33423368 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 290 38 212 0 ENST00000395064.2:c.491C>T p.Ser164Phe p.S164F ENST00000395064 NM_152735.3 164 tCc/tTc 0 +ZEB1 UCSF GRCh37 10 31784732 31784732 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 273 46 279 0 ENST00000361642.5:c.287G>A p.Gly96Glu p.G96E ENST00000361642 NM_001174093.1 96 gGg/gAg 0 +ZFHX3 UCSF GRCh37 16 72821920 72821920 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 68 27 111 0 ENST00000268489.5:c.10255C>T p.Pro3419Ser p.P3419S ENST00000268489 NM_006885.3 3419 Ccc/Tcc 0 +ZFHX4 UCSF GRCh37 8 77766808 77766808 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 250 87 398 0 ENST00000521891.2:c.7651C>T p.Leu2551= p.L2551= ENST00000521891 NM_024721.4 2551 Ctg/Ttg 0 +ZFPM2 UCSF GRCh37 8 106813523 106813523 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 517 58 505 0 ENST00000407775.2:c.1213G>A p.Glu405Lys p.E405K ENST00000407775 NM_012082.3 405 Gaa/Aaa 0 +ZFPM2 UCSF GRCh37 8 106813752 106813752 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 443 84 453 0 ENST00000407775.2:c.1442C>T p.Ser481Leu p.S481L ENST00000407775 NM_012082.3 481 tCa/tTa 0 +ZFYVE26 UCSF GRCh37 14 68282603 68282603 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 105 21 176 0 ENST00000347230.4:c.78G>A p.Arg26= p.R26= ENST00000347230 NM_015346.3 26 agG/agA 0 +ZFYVE9 UCSF GRCh37 1 52811748 52811748 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 110 36 184 0 ENST00000287727.3:c.4133G>A p.Gly1378Glu p.G1378E ENST00000287727 NM_004799.3 1378 gGg/gAg 0 +ZHX2 UCSF GRCh37 8 123964106 123964106 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 252 45 236 1 ENST00000314393.4:c.356C>T p.Thr119Ile p.T119I ENST00000314393 NM_014943.3 119 aCc/aTc 0 +ZHX3 UCSF GRCh37 20 39833299 39833299 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 188 39 202 0 ENST00000309060.3:c.258C>T p.Ser86= p.S86= ENST00000309060 86 tcC/tcT 0 +ZNF107 UCSF GRCh37 7 64168031 64168031 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 102 16 103 0 ENST00000395391.1:c.1349G>A p.Ser450Asn p.S450N ENST00000395391 450 aGc/aAc 0 +ZNF155 UCSF GRCh37 19 44501158 44501158 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 346 95 441 1 ENST00000407951.2:c.1182G>A p.Trp394Ter p.W394* ENST00000407951 NM_001260488.1 394 tgG/tgA 0 +ZNF167 UCSF GRCh37 3 44612356 44612356 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 202 77 332 0 ENST00000273320.3:c.1754G>A p.Gly585Glu p.G585E ENST00000273320 NM_018651.2 585 gGg/gAg 0 +ZNF211 UCSF GRCh37 19 58152509 58152509 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 201 48 289 0 ENST00000299871.5:c.850G>A p.Ala284Thr p.A284T ENST00000299871 NM_001265597.1 284 Gcg/Acg 0 +ZNF217 UCSF GRCh37 20 52192575 52192575 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 118 31 140 0 ENST00000371471.2:c.2728G>A p.Ala910Thr p.A910T ENST00000371471 910 Gca/Aca 0 +ZNF225 UCSF GRCh37 19 44635006 44635006 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 187 145 345 0 ENST00000262894.6:c.239G>A p.Gly80Asp p.G80D ENST00000262894 NM_013362.2 80 gGc/gAc 0 +ZNF248 UCSF GRCh37 10 38120932 38120932 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 338 65 277 1 ENST00000395867.3:c.1351C>T p.Leu451Phe p.L451F ENST00000395867 NM_001267606.1 451 Ctc/Ttc 0 +ZNF267 UCSF GRCh37 16 31925937 31925937 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 138 21 168 0 ENST00000300870.10:c.367G>A p.Glu123Lys p.E123K ENST00000300870 NM_003414.5 123 Gaa/Aaa 0 +ZNF292 UCSF GRCh37 6 87964427 87964427 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 139 81 346 0 ENST00000369577.3:c.1080G>A p.Glu360= p.E360= ENST00000369577 NM_015021.1 360 gaG/gaA 0 +ZNF331 UCSF GRCh37 19 54080807 54080807 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 151 19 207 0 ENST00000253144.9:c.993G>A p.Glu331= p.E331= ENST00000253144 NM_018555.5 331 gaG/gaA 0 +ZNF34 UCSF GRCh37 8 145999772 145999772 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 100 56 229 0 ENST00000343459.4:c.562C>T p.Pro188Ser p.P188S ENST00000343459 188 Cct/Tct 0 +ZNF410 UCSF GRCh37 14 74360506 74360506 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 90 36 167 0 ENST00000442160.3:c.40G>A p.Val14Ile p.V14I ENST00000442160 NM_001242924.1 14 Gta/Ata 0 +ZNF434 UCSF GRCh37 16 3433513 3433513 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 84 27 149 0 ENST00000304926.3:c.797C>T p.Ser266Phe p.S266F ENST00000304926 NM_017810.2 266 tCc/tTc 0 +ZNF444 UCSF GRCh37 19 56658566 56658566 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 10 7 28 0 ENST00000337080.3:c.286G>A p.Glu96Lys p.E96K ENST00000337080 NM_018337.3 96 Gag/Aag 0 +ZNF446 UCSF GRCh37 19 58989194 58989194 + splice_donor_variant Splice_Site SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 23 8 36 0 ENST00000594369.1:c.532+1G>A p.X178_splice ENST00000594369 NM_017908.2 0 +ZNF451 UCSF GRCh37 6 57017100 57017100 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 204 32 165 0 ENST00000370706.4:c.2834C>T p.Pro945Leu p.P945L ENST00000370706 NM_001031623.2 945 cCt/cTt 0 +ZNF454 UCSF GRCh37 5 178373410 178373410 + stop_gained Nonsense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 105 15 203 0 ENST00000320129.3:c.84G>A p.Trp28Ter p.W28* ENST00000320129 NM_182594.2 28 tgG/tgA 0 +ZNF484 UCSF GRCh37 9 95610124 95610124 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 144 33 150 0 ENST00000395506.3:c.951G>A p.Lys317= p.K317= ENST00000395506 317 aaG/aaA 0 +ZNF497 UCSF GRCh37 19 58868933 58868933 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 19 8 36 0 ENST00000311044.3:c.69G>A p.Lys23= p.K23= ENST00000311044 NM_198458.2 23 aaG/aaA 0 +ZNF502 UCSF GRCh37 3 44762784 44762784 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 179 50 243 0 ENST00000296091.4:c.475G>A p.Glu159Lys p.E159K ENST00000296091 NM_001134440.1 159 Gaa/Aaa 0 +ZNF518B UCSF GRCh37 4 10445645 10445645 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 175 55 252 0 ENST00000326756.3:c.2308G>A p.Val770Met p.V770M ENST00000326756 NM_053042.2 770 Gtg/Atg 0 +ZNF546 UCSF GRCh37 19 40520077 40520077 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 194 64 233 0 ENST00000347077.4:c.900C>T p.Pro300= p.P300= ENST00000347077 NM_178544.3 300 ccC/ccT 0 +ZNF551 UCSF GRCh37 19 58196644 58196644 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 367 53 395 0 ENST00000282296.5:c.96G>A p.Glu32= p.E32= ENST00000282296 32 gaG/gaA 0 +ZNF564 UCSF GRCh37 19 12638717 12638717 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 131 52 161 0 ENST00000339282.7:c.205G>A p.Glu69Lys p.E69K ENST00000339282 NM_144976.3 69 Gag/Aag 0 +ZNF595 UCSF GRCh37 4 86793 86793 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 168 46 212 0 ENST00000380882.5:n.1171C>T *391* ENST00000380882 0 +ZNF614 UCSF GRCh37 19 52520123 52520123 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 101 87 160 0 ENST00000270649.6:c.728G>A p.Ser243Asn p.S243N ENST00000270649 NM_025040.3 243 aGt/aAt 0 +ZNF627 UCSF GRCh37 19 11725386 11725386 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 349 89 408 0 ENST00000361113.5:c.48G>A p.Glu16= p.E16= ENST00000361113 NM_145295.3 16 gaG/gaA 0 +ZNF653 UCSF GRCh37 19 11596546 11596546 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 228 45 294 0 ENST00000293771.5:c.1495G>A p.Val499Met p.V499M ENST00000293771 NM_138783.3 499 Gtg/Atg 0 +ZNF660 UCSF GRCh37 3 44636524 44636524 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 73 30 121 0 ENST00000322734.2:c.839G>A p.Gly280Glu p.G280E ENST00000322734 NM_173658.2 280 gGg/gAg 0 +ZNF689 UCSF GRCh37 16 30616479 30616479 + synonymous_variant Silent SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 83 28 176 0 ENST00000287461.3:c.609C>T p.Cys203= p.C203= ENST00000287461 NM_138447.2 203 tgC/tgT 0 +ZNF701 UCSF GRCh37 19 53077350 53077350 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 250 50 294 0 ENST00000540331.1:c.148G>A p.Val50Ile p.V50I ENST00000540331 NM_001172655.1 50 Gta/Ata 0 +ZNF716 UCSF GRCh37 7 57510025 57510025 + stop_gained Nonsense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 108 81 209 0 ENST00000420713.1:c.31C>T p.Arg11Ter p.R11* ENST00000420713 NM_001159279.1 11 Cga/Tga 0 +ZNF808 UCSF GRCh37 19 53058370 53058370 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 493 346 906 1 ENST00000359798.4:c.2201C>T p.Pro734Leu p.P734L ENST00000359798 NM_001039886.3 734 cCt/cTt 0 +ZNF93 UCSF GRCh37 19 20044216 20044216 + missense_variant Missense_Mutation SNP G G A NOVEL P21_Rec Untested WXS Illumina HiSeq 116 33 103 0 ENST00000343769.5:c.452G>A p.Gly151Glu p.G151E ENST00000343769 NM_031218.3 151 gGg/gAg 0 +ZP3 UCSF GRCh37 7 76069815 76069815 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 211 43 345 0 ENST00000394857.3:c.947C>T p.Ala316Val p.A316V ENST00000394857 NM_001110354.1 316 gCt/gTt 0 +ZSCAN2 UCSF GRCh37 15 85164467 85164467 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 187 51 289 0 ENST00000448803.2:c.1041C>T p.Ser347= p.S347= ENST00000448803 NM_181877.3 347 tcC/tcT 0 +ZSCAN2 UCSF GRCh37 15 85165136 85165136 + synonymous_variant Silent SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 207 57 256 0 ENST00000448803.2:c.1710C>T p.Asn570= p.N570= ENST00000448803 NM_181877.3 570 aaC/aaT 0 +ZSWIM5 UCSF GRCh37 1 45525839 45525839 + missense_variant Missense_Mutation SNP C C T NOVEL P21_Rec Untested WXS Illumina HiSeq 94 15 119 0 ENST00000359600.5:c.1033G>A p.Val345Met p.V345M ENST00000359600 NM_020883.1 345 Gtg/Atg 0 +ACVRL1 UCSF GRCh37 12 52309821 52309821 + splice_region_variant,synonymous_variant Splice_Region SNP C C A NOVEL P24_Pri Untested WXS Illumina HiSeq 99 22 89 1 ENST00000388922.4:c.1050C>A p.Gly350= p.G350= ENST00000388922 NM_000020.2 350 ggC/ggA 0 +ASPM UCSF GRCh37 1 197071895 197071895 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Pri Untested WXS Illumina HiSeq 202 119 445 0 ENST00000367409.4:c.6486G>C p.Lys2162Asn p.K2162N ENST00000367409 NM_018136.4 2162 aaG/aaC 0 +ATRX UCSF GRCh37 X 76939340 76939343 + frameshift_variant Frame_Shift_Del DEL CTAC CTAC - NOVEL P24_Pri Untested WXS Illumina HiSeq 53 0 ENST00000373344.5:c.1405_1408delGTAG p.Val469IlefsTer44 p.V469Ifs*44 ENST00000373344 NM_000489.3 469 GTAGat/at 0 +ATRX UCSF GRCh37 X 76920171 76920172 + frameshift_variant Frame_Shift_Del DEL TC TC - NOVEL P24_Pri Untested WXS Illumina HiSeq 15 0 ENST00000373344.5:c.3905_3906del p.Arg1302AsnfsTer6 p.R1302Nfs*6 ENST00000373344 NM_000489.3 1302 aGA/a 0 +CNTN6 UCSF GRCh37 3 1262473 1262473 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Pri Untested WXS Illumina HiSeq 93 11 144 0 ENST00000446702.2:c.158A>G p.Asn53Ser p.N53S ENST00000446702 53 aAt/aGt 0 +CYP4A22 UCSF GRCh37 1 47606476 47606476 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Pri Untested WXS Illumina HiSeq 179 39 258 0 ENST00000371891.3:c.220C>T p.Arg74Trp p.R74W ENST00000371891 NM_001010969.2 74 Cgg/Tgg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Pri Untested WXS Illumina HiSeq 16 3 28 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +MARK4 UCSF GRCh37 19 45769492 45769492 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Pri Untested WXS Illumina HiSeq 130 53 207 0 ENST00000262891.4:c.502G>T p.Ala168Ser p.A168S ENST00000262891 NM_001199867.1 168 Gct/Tct 0 +MTUS1 UCSF GRCh37 8 17504501 17504501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Pri Untested WXS Illumina HiSeq 162 48 269 0 ENST00000262102.6:c.3589G>A p.Ala1197Thr p.A1197T ENST00000262102 NM_001001924.2 1197 Gca/Aca 0 +TMEM55B UCSF GRCh37 14 20927400 20927400 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Pri Untested WXS Illumina HiSeq 35 18 71 0 ENST00000398020.4:c.676G>C p.Gly226Arg p.G226R ENST00000398020 NM_144568.2 226 Ggc/Cgc 0 +TP53 UCSF GRCh37 17 7576858 7576858 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P24_Pri Untested WXS Illumina HiSeq 117 0 ENST00000269305.4:c.988delC p.Leu330PhefsTer15 p.L330Ffs*15 ENST00000269305 NM_001126112.2 330 Ctt/tt 0 +UNC5C UCSF GRCh37 4 96123949 96123949 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Pri Untested WXS Illumina HiSeq 52 16 57 0 ENST00000453304.1:c.2069T>A p.Leu690Gln p.L690Q ENST00000453304 NM_003728.3 690 cTg/cAg 0 +VGLL1 UCSF GRCh37 X 135630884 135630884 + synonymous_variant Silent SNP G G A NOVEL P24_Pri Untested WXS Illumina HiSeq 168 19 207 0 ENST00000370634.3:c.351G>A p.Pro117= p.P117= ENST00000370634 NM_016267.3 117 ccG/ccA 0 +ABHD11 UCSF GRCh37 7 73153014 73153014 + synonymous_variant Silent SNP G G T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 150 20 148 0 ENST00000222800.3:c.114C>A p.Pro38= p.P38= ENST00000222800 NM_148912.2 38 ccC/ccA 0 +AKAP3 UCSF GRCh37 12 4736308 4736308 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec1 Untested WXS Illumina HiSeq 238 36 211 1 ENST00000545990.2:c.1760A>G p.Lys587Arg p.K587R ENST00000545990 NM_001278309.1 587 aAg/aGg 0 +ASB2 UCSF GRCh37 14 94423111 94423111 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 27 5 24 0 ENST00000555019.1:c.311+1G>A p.X104_splice ENST00000555019 NM_001202429.1 0 +ASPM UCSF GRCh37 1 197071895 197071895 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec1 Untested WXS Illumina HiSeq 398 48 445 0 ENST00000367409.4:c.6486G>C p.Lys2162Asn p.K2162N ENST00000367409 NM_018136.4 2162 aaG/aaC 0 +ATRX UCSF GRCh37 X 76939340 76939343 + frameshift_variant Frame_Shift_Del DEL CTAC CTAC - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 30 0 ENST00000373344.5:c.1405_1408delGTAG p.Val469IlefsTer44 p.V469Ifs*44 ENST00000373344 NM_000489.3 469 GTAGat/at 0 +BBS7 UCSF GRCh37 4 122754493 122754493 + missense_variant Missense_Mutation SNP C C A NOVEL P24_Rec1 Untested WXS Illumina HiSeq 80 12 108 0 ENST00000264499.4:c.1569G>T p.Trp523Cys p.W523C ENST00000264499 NM_176824.2 523 tgG/tgT 0 +C4A UCSF GRCh37 6 31996966 31996966 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.041,1000g2011may_all_0.0752,snp132_rs17855807 P24_Rec1 Untested WXS Illumina HiSeq 30 5 41 0 ENST00000435363.2:c.3527G>A p.Ser1176Asn p.S1176N ENST00000435363 NM_001002029.3 1176 aGc/aAc 0 +DROSHA UCSF GRCh37 5 31435970 31435970 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 69 11 67 0 ENST00000344624.3:c.2944G>A p.Val982Ile p.V982I ENST00000344624 982 Gtc/Atc 0 +GLCE UCSF GRCh37 15 69560951 69560951 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 11 0 ENST00000261858.2:c.1222del p.Ala408LeufsTer5 p.A408Lfs*5 ENST00000261858 NM_015554.1 408 Gct/ct 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 27 4 28 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KRT6B UCSF GRCh37 12 52843581 52843581 + synonymous_variant Silent SNP A A G snp132_rs3194297 P24_Rec1 Untested WXS Illumina HiSeq 10 5 12 0 ENST00000252252.3:c.873T>C p.Leu291= p.L291= ENST00000252252 NM_005555.3 291 ctT/ctC 0 +MNS1 UCSF GRCh37 15 56736723 56736723 + frameshift_variant Frame_Shift_Del DEL T T - 1000g2010nov_all P24_Rec1 Untested WXS Illumina HiSeq 6 0 ENST00000260453.3:c.605del p.Lys202SerfsTer9 p.K202Sfs*9 ENST00000260453 NM_018365.2 202 aAg/ag 0 +MS4A6E UCSF GRCh37 11 60105330 60105330 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0042 P24_Rec1 Untested WXS Illumina HiSeq 157 18 193 0 ENST00000300182.4:c.264C>T p.Asp88= p.D88= ENST00000300182 NM_139249.2 88 gaC/gaT 0 +MTUS1 UCSF GRCh37 8 17504501 17504501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 257 49 269 0 ENST00000262102.6:c.3589G>A p.Ala1197Thr p.A1197T ENST00000262102 NM_001001924.2 1197 Gca/Aca 0 +PREX1 UCSF GRCh37 20 47274678 47274678 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec1 Untested WXS Illumina HiSeq 733 84 686 0 ENST00000371941.3:c.1970C>T p.Ala657Val p.A657V ENST00000371941 NM_020820.3 657 gCt/gTt 0 +PRPH UCSF GRCh37 12 49690754 49690754 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 69 8 36 0 ENST00000257860.4:c.785C>T p.Thr262Met p.T262M ENST00000257860 NM_006262.3 262 aCg/aTg 0 +RC3H1 UCSF GRCh37 1 173933175 173933175 + synonymous_variant Silent SNP C C T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 80 9 76 0 ENST00000367696.2:c.1767G>A p.Thr589= p.T589= ENST00000367696 589 acG/acA 0 +SIGLEC5 UCSF GRCh37 19 52132668 52132668 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.008,1000g2011may_all_0.0309,snp132_rs1807124 P24_Rec1 Untested WXS Illumina HiSeq 23 3 17 0 ENST00000429354.3:c.643A>G p.Met215Val p.M215V ENST00000429354 215 Atg/Gtg 0 +TP53 UCSF GRCh37 17 7576858 7576858 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 25 0 ENST00000269305.4:c.988delC p.Leu330PhefsTer15 p.L330Ffs*15 ENST00000269305 NM_001126112.2 330 Ctt/tt 0 +TRRAP UCSF GRCh37 7 98608691 98608694 + frameshift_variant Frame_Shift_Del DEL TCAA TCAA - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 10 0 ENST00000359863.4:c.10913_10916del p.Leu3638ArgfsTer40 p.L3638Rfs*40 ENST00000359863 NM_001244580.1 3638 cTCAAg/cg 0 +TSKS UCSF GRCh37 19 50265271 50265275 + frameshift_variant Frame_Shift_Del DEL GTGAT GTGAT - NOVEL P24_Rec1 Untested WXS Illumina HiSeq 8 0 ENST00000246801.3:c.385_389del p.Ile129GlyfsTer28 p.I129Gfs*28 ENST00000246801 NM_021733.1 129 ATCACg/g 0 +VGLL1 UCSF GRCh37 X 135630884 135630884 + synonymous_variant Silent SNP G G A NOVEL P24_Rec1 Untested WXS Illumina HiSeq 187 43 207 0 ENST00000370634.3:c.351G>A p.Pro117= p.P117= ENST00000370634 NM_016267.3 117 ccG/ccA 0 +ZNF185 UCSF GRCh37 X 152083371 152083371 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec1 Untested WXS Illumina HiSeq 26 7 17 0 ENST00000535861.1:c.152G>A p.Arg51His p.R51H ENST00000535861 NM_001178106.1 51 cGc/cAc 0 +ZNF286B UCSF GRCh37 17 18565409 18565409 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.010,snp132_rs2530065 P24_Rec1 Untested WXS Illumina HiSeq 20 4 29 1 ENST00000545289.1:c.1410T>C p.Ser470= p.S470= ENST00000545289 NM_001145045.1 470 agT/agC 0 +ZNF324 UCSF GRCh37 19 58982237 58982237 + synonymous_variant Silent SNP G G T NOVEL P24_Rec1 Untested WXS Illumina HiSeq 140 16 124 0 ENST00000536459.2:c.378G>T p.Arg126= p.R126= ENST00000536459 126 cgG/cgT 0 +A4GALT UCSF GRCh37 22 43089120 43089120 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 203 26 300 0 ENST00000401850.1:c.838C>T p.Pro280Ser p.P280S ENST00000401850 280 Ccc/Tcc 0 +AACS UCSF GRCh37 12 125626687 125626687 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 9 60 0 ENST00000316519.6:c.1931C>T p.Ala644Val p.A644V ENST00000316519 NM_023928.3 644 gCt/gTt 0 +AACS UCSF GRCh37 12 125561117 125561117 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 3 37 0 ENST00000316519.6:c.318G>A p.Leu106= p.L106= ENST00000316519 NM_023928.3 106 ctG/ctA 0 +AASS UCSF GRCh37 7 121755269 121755269 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 22 205 0 ENST00000393376.1:c.902C>T p.Pro301Leu p.P301L ENST00000393376 301 cCc/cTc 0 +ABCA10 UCSF GRCh37 17 67190083 67190083 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 77 404 0 ENST00000269081.4:c.1393G>A p.Glu465Lys p.E465K ENST00000269081 NM_080282.3 465 Gaa/Aaa 0 +ABCA13 UCSF GRCh37 7 48559782 48559782 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 87 275 0 ENST00000435803.1:c.13943C>T p.Pro4648Leu p.P4648L ENST00000435803 NM_152701.3 4648 cCc/cTc 0 +ABCA2 UCSF GRCh37 9 139905759 139905759 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 20 164 0 ENST00000341511.6:c.5802C>T p.Asp1934= p.D1934= ENST00000341511 NM_212533.2 1934 gaC/gaT 0 +ABCA4 UCSF GRCh37 1 94546205 94546205 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 10 99 0 ENST00000370225.3:c.928G>A p.Glu310Lys p.E310K ENST00000370225 NM_000350.2 310 Gag/Aag 0 +ABCA6 UCSF GRCh37 17 67102285 67102285 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 9 94 0 ENST00000284425.2:c.2457C>T p.Ser819= p.S819= ENST00000284425 NM_080284.2 819 tcC/tcT 0 +ABCB1 UCSF GRCh37 7 87160729 87160729 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 20 192 0 ENST00000265724.3:c.2566C>T p.Gln856Ter p.Q856* ENST00000265724 NM_000927.4 856 Caa/Taa 0 +ABCB10 UCSF GRCh37 1 229654102 229654102 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 20 184 0 ENST00000344517.4:c.2041G>A p.Asp681Asn p.D681N ENST00000344517 NM_012089.2 681 Gat/Aat 0 +ABCB11 UCSF GRCh37 2 169833173 169833173 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 8 113 0 ENST00000263817.6:c.1222G>A p.Glu408Lys p.E408K ENST00000263817 NM_003742.2 408 Gaa/Aaa 0 +ABCB11 UCSF GRCh37 2 169788987 169788987 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 11 61 0 ENST00000263817.6:c.3113C>T p.Thr1038Ile p.T1038I ENST00000263817 NM_003742.2 1038 aCc/aTc 0 +ABCB11 UCSF GRCh37 2 169792807 169792807 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 12 78 0 ENST00000263817.6:c.2747C>T p.Ala916Val p.A916V ENST00000263817 NM_003742.2 916 gCc/gTc 0 +ABCB4 UCSF GRCh37 7 87049328 87049328 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 34 247 0 ENST00000265723.4:c.2380G>A p.Ala794Thr p.A794T ENST00000265723 NM_000443.3 794 Gca/Aca 0 +ABCB5 UCSF GRCh37 7 20766690 20766690 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 37 0 ENST00000404938.2:c.2653C>T p.Arg885Cys p.R885C ENST00000404938 NM_001163941.1 885 Cgt/Tgt 0 +ABCC4 UCSF GRCh37 13 95696034 95696034 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 10 88 0 ENST00000376887.4:c.3637G>A p.Glu1213Lys p.E1213K ENST00000376887 NM_005845.3 1213 Gag/Aag 0 +ABCC6 UCSF GRCh37 16 16284056 16284056 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 5 47 0 ENST00000205557.7:c.1600G>A p.Val534Met p.V534M ENST00000205557 NM_001171.5 534 Gtg/Atg 0 +ABCC8 UCSF GRCh37 11 17449921 17449921 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 16 149 0 ENST00000389817.3:c.1955C>T p.Ala652Val p.A652V ENST00000389817 652 gCc/gTc 0 +ABCD1 UCSF GRCh37 X 153002673 153002673 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 5 40 0 ENST00000218104.3:c.1456G>A p.Gly486Arg p.G486R ENST00000218104 NM_000033.3 486 Gga/Aga 0 +ABCD2 UCSF GRCh37 12 40012872 40012872 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.002,1000g2011may_all_0.0042,snp132_rs35217341 P24_Rec2 Untested WXS Illumina HiSeq 225 31 263 0 ENST00000308666.3:c.546C>T p.His182= p.H182= ENST00000308666 NM_005164.3 182 caC/caT 0 +ABCD4 UCSF GRCh37 14 74761851 74761851 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 211 26 309 0 ENST00000356924.4:c.719G>A p.Arg240Lys p.R240K ENST00000356924 NM_005050.3 240 aGa/aAa 0 +ABCF1 UCSF GRCh37 6 30547723 30547723 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 3 25 0 ENST00000326195.8:c.505C>T p.Gln169Ter p.Q169* ENST00000326195 NM_001025091.1 169 Cag/Tag 0 +ABCF1 UCSF GRCh37 6 30550959 30550959 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 15 123 0 ENST00000326195.8:c.909C>T p.Asp303= p.D303= ENST00000326195 NM_001025091.1 303 gaC/gaT 0 +ABCF1 UCSF GRCh37 6 30553437 30553437 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 9 106 0 ENST00000326195.8:c.1578C>T p.Leu526= p.L526= ENST00000326195 NM_001025091.1 526 ctC/ctT 0 +ABCF3 UCSF GRCh37 3 183905677 183905677 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 10 85 0 ENST00000429586.2:c.475G>A p.Ala159Thr p.A159T ENST00000429586 NM_018358.2 159 Gca/Aca 0 +ABCF3 UCSF GRCh37 3 183910922 183910922 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 18 136 0 ENST00000429586.2:c.1783G>A p.Gly595Ser p.G595S ENST00000429586 NM_018358.2 595 Ggt/Agt 0 +ABCG8 UCSF GRCh37 2 44079759 44079759 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 27 318 0 ENST00000272286.2:c.716C>T p.Pro239Leu p.P239L ENST00000272286 NM_022437.2 239 cCc/cTc 0 +ABHD4 UCSF GRCh37 14 23072957 23072957 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 12 89 0 ENST00000428304.2:c.613G>A p.Ala205Thr p.A205T ENST00000428304 NM_022060.2 205 Gct/Act 0 +ABI3BP UCSF GRCh37 3 100568891 100568891 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 18 124 0 ENST00000284322.5:c.1373C>T p.Pro458Leu p.P458L ENST00000284322 NM_015429.3 458 cCt/cTt 0 +ABL1 UCSF GRCh37 9 133738375 133738375 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 6 47 0 ENST00000318560.5:c.775G>A p.Gly259Ser p.G259S ENST00000318560 NM_005157.4 259 Ggc/Agc 0 +ABRA UCSF GRCh37 8 107781887 107781887 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 73 249 0 ENST00000311955.3:c.532G>A p.Glu178Lys p.E178K ENST00000311955 NM_139166.4 178 Gag/Aag 0 +ACACA UCSF GRCh37 17 35518718 35518718 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 51 0 ENST00000353139.5:c.5326G>A p.Val1776Ile p.V1776I ENST00000353139 NM_198834.1 1776 Gta/Ata 0 +ACACB UCSF GRCh37 12 109623490 109623490 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 15 171 0 ENST00000338432.7:c.1925C>T p.Pro642Leu p.P642L ENST00000338432 642 cCc/cTc 0 +ACACB UCSF GRCh37 12 109629491 109629491 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 21 196 0 ENST00000338432.7:c.2218C>T p.Leu740Phe p.L740F ENST00000338432 740 Ctc/Ttc 0 +ACAD11 UCSF GRCh37 3 132360879 132360879 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 37 268 0 ENST00000264990.6:c.474C>T p.Ser158= p.S158= ENST00000264990 NM_032169.4 158 tcC/tcT 0 +ACAP1 UCSF GRCh37 17 7252391 7252391 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 21 154 0 ENST00000158762.3:c.1756C>T p.Pro586Ser p.P586S ENST00000158762 NM_014716.3 586 Ccc/Tcc 0 +ACBD6 UCSF GRCh37 1 180471299 180471299 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 273 43 366 0 ENST00000367595.3:c.103G>A p.Glu35Lys p.E35K ENST00000367595 NM_032360.3 35 Gag/Aag 0 +ACCN2 UCSF GRCh37 12 50474479 50474479 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 17 163 0 ENST00000228468.4:c.1404C>T p.Pro468= p.P468= ENST00000228468 NM_020039.3 468 ccC/ccT 0 +ACE UCSF GRCh37 17 61557699 61557699 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 12 47 0 ENST00000290866.4:c.657C>T p.Gly219= p.G219= ENST00000290866 NM_000789.3 219 ggC/ggT 0 +ACSBG1 UCSF GRCh37 15 78526734 78526734 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 31 214 0 ENST00000258873.4:c.110C>T p.Thr37Ile p.T37I ENST00000258873 NM_001199377.1 37 aCc/aTc 0 +ACSS2 UCSF GRCh37 20 33470605 33470605 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 75 0 ENST00000253382.5:c.187G>A p.Gly63Arg p.G63R ENST00000253382 NM_001076552.2 63 Gga/Aga 0 +ACSS2 UCSF GRCh37 20 33507237 33507237 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 29 178 0 ENST00000253382.5:c.874-1G>A p.X292_splice ENST00000253382 NM_001076552.2 0 +ACTA1 UCSF GRCh37 1 229568828 229568828 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 48 0 ENST00000366684.3:c.35G>A p.Cys12Tyr p.C12Y ENST00000366684 NM_001100.3 12 tGc/tAc 0 +ACTB UCSF GRCh37 7 5567397 5567397 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 9 0 ENST00000331789.5:c.1110C>T p.Val370= p.V370= ENST00000331789 NM_001101.3 370 gtC/gtT 0 +ACTL7B UCSF GRCh37 9 111616998 111616998 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 19 163 0 ENST00000374667.3:c.1213G>A p.Glu405Lys p.E405K ENST00000374667 NM_006686.3 405 Gag/Aag 0 +ACTL7B UCSF GRCh37 9 111617665 111617665 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 28 257 0 ENST00000374667.3:c.546G>A p.Ser182= p.S182= ENST00000374667 NM_006686.3 182 tcG/tcA 0 +ACTL8 UCSF GRCh37 1 18152819 18152819 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 33 229 0 ENST00000375406.1:c.906C>T p.Thr302= p.T302= ENST00000375406 NM_030812.2 302 acC/acT 0 +ACTN4 UCSF GRCh37 19 39214964 39214964 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 23 126 0 ENST00000252699.2:c.1860C>T p.Asn620= p.N620= ENST00000252699 NM_004924.4 620 aaC/aaT 0 +ACTR5 UCSF GRCh37 20 37380900 37380900 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 9 60 0 ENST00000243903.4:c.732G>A p.Glu244= p.E244= ENST00000243903 NM_024855.3 244 gaG/gaA 0 +ACVR1B UCSF GRCh37 12 52387891 52387891 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 10 52 0 ENST00000541224.1:c.1638C>T p.Ile546= p.I546= ENST00000541224 546 atC/atT 0 +ADAM12 UCSF GRCh37 10 127753543 127753543 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 5 38 0 ENST00000368679.4:c.1450G>A p.Asp484Asn p.D484N ENST00000368679 NM_003474.4 484 Gac/Aac 0 +ADAM12 UCSF GRCh37 10 127760187 127760187 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 192 50 445 0 ENST00000368679.4:c.1191G>A p.Arg397= p.R397= ENST00000368679 NM_003474.4 397 agG/agA 0 +ADAM17 UCSF GRCh37 2 9630458 9630458 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 58 172 0 ENST00000310823.3:c.2323G>A p.Asp775Asn p.D775N ENST00000310823 NM_003183.4 775 Gat/Aat 0 +ADAM22 UCSF GRCh37 7 87760657 87760657 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 192 33 300 0 ENST00000265727.7:c.899C>T p.Ala300Val p.A300V ENST00000265727 300 gCc/gTc 0 +ADAM9 UCSF GRCh37 8 38913251 38913251 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 37 177 0 ENST00000487273.2:c.1551C>T p.Cys517= p.C517= ENST00000487273 NM_003816.2 517 tgC/tgT 0 +ADAMTS1 UCSF GRCh37 21 28217227 28217227 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 27 189 0 ENST00000284984.3:c.47G>A p.Ser16Asn p.S16N ENST00000284984 NM_006988.3 16 aGc/aAc 0 +ADAMTS13 UCSF GRCh37 9 136310022 136310022 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 36 108 0 ENST00000371929.3:c.2459G>A p.Gly820Asp p.G820D ENST00000371929 NM_139025.4 820 gGt/gAt 0 +ADAMTS13 UCSF GRCh37 9 136314999 136314999 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 30 0 ENST00000371929.3:c.2957G>A p.Gly986Asp p.G986D ENST00000371929 NM_139025.4 986 gGt/gAt 0 +ADAMTS18 UCSF GRCh37 16 77396097 77396097 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 10 76 0 ENST00000282849.5:c.1121C>T p.Ala374Val p.A374V ENST00000282849 NM_199355.2 374 gCc/gTc 0 +ADAMTS19 UCSF GRCh37 5 128983457 128983457 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 22 215 0 ENST00000274487.4:c.1855-1G>A p.X619_splice ENST00000274487 NM_133638.3 0 +ADAMTS5 UCSF GRCh37 21 28296430 28296430 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 391 60 490 0 ENST00000284987.5:c.2735G>A p.Gly912Glu p.G912E ENST00000284987 NM_007038.3 912 gGa/gAa 0 +ADAMTS6 UCSF GRCh37 5 64766794 64766794 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 38 277 0 ENST00000381055.3:c.273C>T p.Ala91= p.A91= ENST00000381055 NM_197941.2 91 gcC/gcT 0 +ADCK2 UCSF GRCh37 7 140373796 140373796 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 35 207 0 ENST00000072869.4:c.666C>T p.Ala222= p.A222= ENST00000072869 NM_052853.3 222 gcC/gcT 0 +ADCY10 UCSF GRCh37 1 167805696 167805696 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 9 84 0 ENST00000367851.4:c.3160C>T p.Pro1054Ser p.P1054S ENST00000367851 NM_018417.4 1054 Cct/Tct 0 +ADCY10 UCSF GRCh37 1 167852699 167852699 + synonymous_variant Silent SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 33 135 0 ENST00000367851.4:c.996C>A p.Ile332= p.I332= ENST00000367851 NM_018417.4 332 atC/atA 0 +ADCY8 UCSF GRCh37 8 132052082 132052082 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 21 101 0 ENST00000286355.5:c.498G>A p.Leu166= p.L166= ENST00000286355 NM_001115.2 166 ttG/ttA 0 +ADD2 UCSF GRCh37 2 70900457 70900457 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 18 150 0 ENST00000264436.4:c.1742-319G>A *581* ENST00000264436 NM_001617.3 0 +ADRBK1 UCSF GRCh37 11 67050605 67050605 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 143 404 0 ENST00000308595.5:c.1234G>A p.Glu412Lys p.E412K ENST00000308595 NM_001619.3 412 Gag/Aag 0 +ADRBK1 UCSF GRCh37 11 67049810 67049810 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 21 128 0 ENST00000308595.5:c.1026C>T p.Phe342= p.F342= ENST00000308595 NM_001619.3 342 ttC/ttT 0 +AEN UCSF GRCh37 15 89172585 89172585 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 40 0 ENST00000332810.3:c.669G>A p.Glu223= p.E223= ENST00000332810 NM_022767.3 223 gaG/gaA 0 +AFAP1 UCSF GRCh37 4 7802206 7802206 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 27 255 0 ENST00000420658.1:c.1229G>A p.Arg410Gln p.R410Q ENST00000420658 NM_001134647.1 410 cGg/cAg 0 +AFAP1 UCSF GRCh37 4 7774616 7774616 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 228 43 320 0 ENST00000420658.1:c.2184G>A p.Lys728= p.K728= ENST00000420658 NM_001134647.1 728 aaG/aaA 0 +AFAP1L2 UCSF GRCh37 10 116064684 116064684 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 4 45 0 ENST00000304129.4:c.1078C>T p.Leu360= p.L360= ENST00000304129 NM_001287824.1 360 Ctg/Ttg 0 +AFF3 UCSF GRCh37 2 100203737 100203737 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 21 197 0 ENST00000356421.2:c.2545G>A p.Asp849Asn p.D849N ENST00000356421 NM_001025108.1 849 Gac/Aac 0 +AGER UCSF GRCh37 6 32151714 32151714 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 26 192 0 ENST00000375076.4:c.103G>A p.Val35Met p.V35M ENST00000375076 NM_001206929.1 35 Gtg/Atg 0 +AGFG2 UCSF GRCh37 7 100159897 100159897 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.0012 P24_Rec2 Untested WXS Illumina HiSeq 51 9 85 0 ENST00000300176.4:c.893C>T p.Thr298Ile p.T298I ENST00000300176 NM_006076.4 298 aCt/aTt 0 +AGK UCSF GRCh37 7 141349127 141349127 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 281 37 294 0 ENST00000355413.4:c.1040C>T p.Thr347Ile p.T347I ENST00000355413 NM_018238.3 347 aCt/aTt 0 +AGL UCSF GRCh37 1 100335995 100335995 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 31 263 0 ENST00000294724.4:c.704C>T p.Ala235Val p.A235V ENST00000294724 NM_000028.2 235 gCc/gTc 0 +AHNAK2 UCSF GRCh37 14 105404793 105404793 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 23 198 0 ENST00000333244.5:c.16995C>T p.Ser5665= p.S5665= ENST00000333244 NM_138420.2 5665 tcC/tcT 0 +AIF1 UCSF GRCh37 6 31583111 31583111 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 23 72 0 ENST00000376059.3:c.5G>A p.Ser2Asn p.S2N ENST00000376059 NM_001623.3 2 aGc/aAc 0 +AIM1L UCSF GRCh37 1 26670384 26670384 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 15 159 0 ENST00000527815.1:c.143C>T p.Thr48Ile p.T48I ENST00000527815 NM_001039775.3 48 aCc/aTc 0 +AIM2 UCSF GRCh37 1 159036072 159036072 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 22 170 0 ENST00000368130.4:c.444G>A p.Gly148= p.G148= ENST00000368130 NM_004833.1 148 ggG/ggA 0 +AK5 UCSF GRCh37 1 77752629 77752629 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 5 68 0 ENST00000354567.2:c.64C>T p.Leu22Phe p.L22F ENST00000354567 NM_174858.2 22 Ctt/Ttt 0 +AKAP13 UCSF GRCh37 15 86123161 86123161 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 24 221 0 ENST00000361243.2:c.1862C>T p.Ala621Val p.A621V ENST00000361243 NM_006738.5 621 gCc/gTc 0 +AKAP3 UCSF GRCh37 12 4736308 4736308 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 120 211 1 ENST00000545990.2:c.1760A>G p.Lys587Arg p.K587R ENST00000545990 NM_001278309.1 587 aAg/aGg 0 +AKAP4 UCSF GRCh37 X 49958781 49958781 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 27 152 0 ENST00000358526.2:c.583C>T p.Pro195Ser p.P195S ENST00000358526 NM_003886.2 195 Cca/Tca 0 +AKAP5 UCSF GRCh37 14 64935379 64935379 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 36 350 0 ENST00000394718.4:c.267G>A p.Arg89= p.R89= ENST00000394718 NM_004857.3 89 agG/agA 0 +AKAP6 UCSF GRCh37 14 33046377 33046377 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 14 103 0 ENST00000280979.4:c.2398G>A p.Glu800Lys p.E800K ENST00000280979 NM_004274.4 800 Gaa/Aaa 0 +AKAP8 UCSF GRCh37 19 15479045 15479045 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 725 86 656 0 ENST00000269701.2:c.1160+1G>A p.X387_splice ENST00000269701 NM_005858.3 0 +ALAS1 UCSF GRCh37 3 52240740 52240740 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 283 37 411 0 ENST00000394965.2:c.1138G>A p.Ala380Thr p.A380T ENST00000394965 NM_000688.5 380 Gca/Aca 0 +ALDH1L1 UCSF GRCh37 3 125833449 125833449 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 18 152 0 ENST00000273450.3:c.2063C>T p.Ser688Leu p.S688L ENST00000273450 NM_001270364.1 688 tCa/tTa 0 +ALDH1L1 UCSF GRCh37 3 125879707 125879707 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 13 72 0 ENST00000273450.3:c.146C>T p.Ala49Val p.A49V ENST00000273450 NM_001270364.1 49 gCc/gTc 0 +ALDH6A1 UCSF GRCh37 14 74531550 74531550 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 27 247 0 ENST00000553458.1:c.1478G>A p.Gly493Glu p.G493E ENST00000553458 NM_001278593.1 493 gGa/gAa 0 +ALG2 UCSF GRCh37 9 101980970 101980970 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 6 74 0 ENST00000476832.1:c.497C>T p.Thr166Ile p.T166I ENST00000476832 NM_033087.3 166 aCc/aTc 0 +ALKBH2 UCSF GRCh37 12 109526108 109526108 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 12 114 0 ENST00000429722.2:c.689C>T p.Thr230Ile p.T230I ENST00000429722 NM_001145374.1 230 aCc/aTc 0 +ALLC UCSF GRCh37 2 3749131 3749131 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 8 66 0 ENST00000252505.3:c.880G>A p.Gly294Arg p.G294R ENST00000252505 NM_018436.3 294 Ggg/Agg 0 +ALMS1 UCSF GRCh37 2 73676891 73676891 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 443 76 650 0 ENST00000264448.6:c.3234C>T p.Phe1078= p.F1078= ENST00000264448 NM_015120.4 1078 ttC/ttT 0 +ALMS1 UCSF GRCh37 2 73800038 73800038 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 12 118 0 ENST00000264448.6:c.11031G>A p.Arg3677= p.R3677= ENST00000264448 NM_015120.4 3677 cgG/cgA 0 +ALPI UCSF GRCh37 2 233321741 233321741 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 47 0 ENST00000295463.3:c.433G>A p.Gly145Ser p.G145S ENST00000295463 NM_001631.3 145 Ggc/Agc 0 +ALPK1 UCSF GRCh37 4 113352584 113352584 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 45 482 0 ENST00000458497.1:c.1881G>A p.Glu627= p.E627= ENST00000458497 NM_001102406.1 627 gaG/gaA 0 +ALPK2 UCSF GRCh37 18 56205132 56205132 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 282 47 354 0 ENST00000361673.3:c.2287G>A p.Asp763Asn p.D763N ENST00000361673 NM_052947.3 763 Gat/Aat 0 +ALPK2 UCSF GRCh37 18 56246191 56246191 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 209 122 444 0 ENST00000361673.3:c.1817C>T p.Thr606Ile p.T606I ENST00000361673 NM_052947.3 606 aCc/aTc 0 +ALPL UCSF GRCh37 1 21894608 21894608 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 41 144 0 ENST00000374840.3:c.660G>A p.Gly220= p.G220= ENST00000374840 NM_000478.4 220 ggG/ggA 0 +ALX4 UCSF GRCh37 11 44286642 44286642 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 12 80 0 ENST00000329255.3:c.998C>T p.Ser333Phe p.S333F ENST00000329255 NM_021926.3 333 tCc/tTc 0 +AMDHD1 UCSF GRCh37 12 96354252 96354252 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 26 303 0 ENST00000266736.2:c.664G>A p.Gly222Arg p.G222R ENST00000266736 NM_152435.2 222 Ggg/Agg 0 +AMHR2 UCSF GRCh37 12 53825207 53825207 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 603 97 843 0 ENST00000257863.4:c.1672G>A p.Gly558Ser p.G558S ENST00000257863 NM_001164690.1 558 Ggc/Agc 0 +AMPD2 UCSF GRCh37 1 110167963 110167963 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 248 53 320 0 ENST00000256578.3:c.292G>A p.Ala98Thr p.A98T ENST00000256578 NM_004037.7 98 Gcc/Acc 0 +ANGPTL5 UCSF GRCh37 11 101773398 101773398 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 17 228 0 ENST00000334289.3:c.494G>A p.Ser165Asn p.S165N ENST00000334289 NM_178127.4 165 aGt/aAt 0 +ANKAR UCSF GRCh37 2 190595295 190595295 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 12 115 0 ENST00000520309.1:c.3268C>T p.Leu1090= p.L1090= ENST00000520309 NM_144708.3 1090 Cta/Tta 0 +ANKHD1 UCSF GRCh37 5 139838875 139838875 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 8 97 0 ENST00000297183.6:c.1607C>T p.Ser536Phe p.S536F ENST00000297183 NM_020690.5 536 tCc/tTc 0 +ANKLE1 UCSF GRCh37 19 17394429 17394429 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 384 47 372 0 ENST00000394458.3:c.856G>A p.Ala286Thr p.A286T ENST00000394458 NM_001278444.1 286 Gct/Act 0 +ANKRD13D UCSF GRCh37 11 67059142 67059142 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 36 271 0 ENST00000511455.2:c.466G>A p.Val156Ile p.V156I ENST00000511455 NM_207354.2 156 Gta/Ata 0 +ANKRD40 UCSF GRCh37 17 48776819 48776819 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 12 61 0 ENST00000285243.6:c.719G>A p.Gly240Glu p.G240E ENST00000285243 NM_052855.3 240 gGa/gAa 0 +ANKRD44 UCSF GRCh37 2 197946370 197946370 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 3 33 0 ENST00000282272.8:c.1513C>T p.Leu505= p.L505= ENST00000282272 NM_001195144.1 505 Cta/Tta 0 +ANKS1B UCSF GRCh37 12 99548209 99548209 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 12 58 0 ENST00000547776.2:c.2420-36C>T *807* ENST00000547776 NM_152788.4 0 +ANKS3 UCSF GRCh37 16 4752160 4752160 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 10 48 0 ENST00000304283.4:c.952G>A p.Val318Ile p.V318I ENST00000304283 NM_133450.3 318 Gtc/Atc 0 +ANO2 UCSF GRCh37 12 5685114 5685114 + missense_variant Missense_Mutation SNP T T A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 280 73 228 0 ENST00000327087.8:c.2507A>T p.Asn836Ile p.N836I ENST00000327087 NM_001278596.1 836 aAt/aTt 0 +ANTXR1 UCSF GRCh37 2 69330008 69330008 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 14 132 0 ENST00000303714.4:c.738C>T p.Phe246= p.F246= ENST00000303714 NM_032208.2 246 ttC/ttT 0 +ANTXR2 UCSF GRCh37 4 80992803 80992803 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 25 275 0 ENST00000307333.7:c.158G>A p.Gly53Glu p.G53E ENST00000307333 NM_001145794.1 53 gGg/gAg 0 +AOC3 UCSF GRCh37 17 41004671 41004671 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 209 29 329 0 ENST00000308423.2:c.1311C>T p.Gly437= p.G437= ENST00000308423 NM_003734.3 437 ggC/ggT 0 +AP3B1 UCSF GRCh37 5 77452093 77452093 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 229 30 388 0 ENST00000255194.6:c.1462G>A p.Asp488Asn p.D488N ENST00000255194 488 Gac/Aac 0 +AP3B2 UCSF GRCh37 15 83349459 83349459 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 43 210 0 ENST00000261722.3:c.820G>A p.Glu274Lys p.E274K ENST00000261722 NM_004644.4 274 Gag/Aag 0 +AP3D1 UCSF GRCh37 19 2115382 2115382 + missense_variant Missense_Mutation SNP C C T snp132_rs34098352 P24_Rec2 Untested WXS Illumina HiSeq 402 45 371 0 ENST00000355272.6:c.2185G>A p.Glu729Lys p.E729K ENST00000355272 NM_001261826.1 729 Gag/Aag 0 +AP3D1 UCSF GRCh37 19 2110730 2110730 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 28 0 ENST00000355272.6:c.3151C>T p.Pro1051Ser p.P1051S ENST00000355272 NM_001261826.1 1051 Ccc/Tcc 0 +AP4B1 UCSF GRCh37 1 114438498 114438498 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 18 149 0 ENST00000369569.1:c.1673C>T p.Ser558Leu p.S558L ENST00000369569 NM_001253852.1 558 tCa/tTa 0 +APBA1 UCSF GRCh37 9 72067119 72067119 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 23 258 0 ENST00000265381.4:c.1887G>A p.Lys629= p.K629= ENST00000265381 NM_001163.3 629 aaG/aaA 0 +APEH UCSF GRCh37 3 49713502 49713502 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 337 62 424 0 ENST00000296456.5:c.456C>T p.Cys152= p.C152= ENST00000296456 NM_001640.3 152 tgC/tgT 0 +APH1B UCSF GRCh37 15 63597957 63597957 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 275 39 393 0 ENST00000261879.5:c.751C>T p.Leu251Phe p.L251F ENST00000261879 NM_031301.3 251 Ctt/Ttt 0 +APITD1 UCSF GRCh37 1 10500457 10500457 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 8 93 0 ENST00000400900.2:c.263G>A p.Arg88Lys p.R88K ENST00000400900 88 aGg/aAg 0 +APLF UCSF GRCh37 2 68753356 68753356 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 15 106 0 ENST00000303795.4:c.786G>A p.Glu262= p.E262= ENST00000303795 NM_173545.2 262 gaG/gaA 0 +APLNR UCSF GRCh37 11 57003475 57003475 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 42 273 0 ENST00000606794.1:c.1004C>T p.Ser335Phe p.S335F ENST00000606794 NM_005161.4 335 tCc/tTc 0 +APOA5 UCSF GRCh37 11 116660927 116660927 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 31 209 0 ENST00000542499.1:c.1018C>T p.Leu340= p.L340= ENST00000542499 NM_001166598.1 340 Ctg/Ttg 0 +APOB UCSF GRCh37 2 21228815 21228815 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 270 51 391 0 ENST00000233242.1:c.10925G>A p.Gly3642Glu p.G3642E ENST00000233242 NM_000384.2 3642 gGg/gAg 0 +APOB UCSF GRCh37 2 21236226 21236226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 45 171 1 ENST00000233242.1:c.4022C>T p.Thr1341Ile p.T1341I ENST00000233242 NM_000384.2 1341 aCc/aTc 0 +APOBEC3B UCSF GRCh37 22 39382097 39382097 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 10 93 0 ENST00000333467.3:c.454+1G>A p.X152_splice ENST00000333467 NM_004900.4 0 +APOD UCSF GRCh37 3 195295876 195295876 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 31 117 0 ENST00000343267.3:c.465C>T p.Leu155= p.L155= ENST00000343267 NM_001647.3 155 ctC/ctT 0 +APOH UCSF GRCh37 17 64210600 64210600 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 21 203 0 ENST00000205948.6:c.953G>A p.Gly318Asp p.G318D ENST00000205948 NM_000042.2 318 gGc/gAc 0 +APOL3 UCSF GRCh37 22 36537471 36537471 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 177 34 260 0 ENST00000349314.2:c.986C>T p.Thr329Ile p.T329I ENST00000349314 NM_145640.2 329 aCc/aTc 0 +APOL4 UCSF GRCh37 22 36587897 36587897 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 36 307 0 ENST00000352371.1:c.280G>A p.Asp94Asn p.D94N ENST00000352371 94 Gac/Aac 0 +APOL6 UCSF GRCh37 22 36055273 36055273 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 21 139 0 ENST00000409652.4:c.662C>T p.Ala221Val p.A221V ENST00000409652 NM_030641.3 221 gCc/gTc 0 +APPL1 UCSF GRCh37 3 57291453 57291453 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 20 188 0 ENST00000288266.3:c.1427G>A p.Gly476Asp p.G476D ENST00000288266 NM_012096.2 476 gGc/gAc 0 +AQP10 UCSF GRCh37 1 154295472 154295472 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 82 0 ENST00000324978.3:c.247C>T p.Pro83Ser p.P83S ENST00000324978 NM_080429.2 83 Cca/Tca 0 +ARAP3 UCSF GRCh37 5 141036200 141036200 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 17 122 0 ENST00000239440.4:c.3660C>T p.Ile1220= p.I1220= ENST00000239440 NM_022481.5 1220 atC/atT 0 +ARC UCSF GRCh37 8 143694825 143694825 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 21 252 0 ENST00000356613.2:c.808G>A p.Glu270Lys p.E270K ENST00000356613 NM_015193.4 270 Gag/Aag 0 +ARHGAP20 UCSF GRCh37 11 110477462 110477462 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 16 199 0 ENST00000260283.4:c.787C>T p.Pro263Ser p.P263S ENST00000260283 NM_020809.3 263 Cca/Tca 0 +ARHGAP28 UCSF GRCh37 18 6896535 6896535 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 10 120 0 ENST00000419673.2:c.1463C>T p.Ala488Val p.A488V ENST00000419673 NM_001010000.2 488 gCt/gTt 0 +ARHGAP29 UCSF GRCh37 1 94645456 94645456 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 16 113 0 ENST00000260526.6:c.2305G>A p.Glu769Lys p.E769K ENST00000260526 NM_004815.3 769 Gag/Aag 0 +ARHGAP30 UCSF GRCh37 1 161021503 161021503 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 16 108 0 ENST00000368013.3:c.1021C>T p.Pro341Ser p.P341S ENST00000368013 NM_181720.2 341 Cca/Tca 0 +ARHGAP39 UCSF GRCh37 8 145773405 145773405 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 41 245 0 ENST00000377307.2:c.1065G>A p.Pro355= p.P355= ENST00000377307 NM_025251.1 355 ccG/ccA 0 +ARHGAP44 UCSF GRCh37 17 12887937 12887937 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 28 194 0 ENST00000379672.5:c.2029G>A p.Val677Ile p.V677I ENST00000379672 NM_014859.4 677 Gtc/Atc 0 +ARHGAP6 UCSF GRCh37 X 11157559 11157559 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 9 51 0 ENST00000337414.4:c.2349G>A p.Trp783Ter p.W783* ENST00000337414 NM_013427.2 783 tgG/tgA 0 +ARHGAP9 UCSF GRCh37 12 57871385 57871385 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 308 40 33 0 ENST00000393791.3:c.613C>T p.Pro205Ser p.P205S ENST00000393791 NM_032496.2 205 Ccc/Tcc 0 +ARHGEF16 UCSF GRCh37 1 3386008 3386008 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 12 111 0 ENST00000378378.4:c.873G>A p.Glu291= p.E291= ENST00000378378 NM_014448.3 291 gaG/gaA 0 +ARHGEF18 UCSF GRCh37 19 7516038 7516038 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 38 174 0 ENST00000359920.6:c.1177A>T p.Ile393Phe p.I393F ENST00000359920 NM_001130955.1 393 Att/Ttt 0 +ARHGEF2 UCSF GRCh37 1 155935512 155935512 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 4 42 0 ENST00000361247.4:c.380C>T p.Ser127Phe p.S127F ENST00000361247 NM_001162384.1 127 tCc/tTc 0 +ARHGEF26 UCSF GRCh37 3 153840604 153840604 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 12 67 0 ENST00000356448.4:c.823C>T p.Leu275Phe p.L275F ENST00000356448 NM_001251962.1 275 Ctc/Ttc 0 +ARHGEF33 UCSF GRCh37 2 39178263 39178263 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 187 23 245 0 ENST00000409978.1:c.1053+1G>A p.X351_splice ENST00000409978 0 +ARHGEF38 UCSF GRCh37 4 106588455 106588455 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 97 340 0 ENST00000420470.2:c.1859G>A p.Ser620Asn p.S620N ENST00000420470 NM_001242729.1 620 aGt/aAt 0 +ARHGEF7 UCSF GRCh37 13 111935647 111935647 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 8 50 0 ENST00000375741.2:c.1950G>A p.Trp650Ter p.W650* ENST00000375741 NM_145735.2 650 tgG/tgA 0 +ARID1B UCSF GRCh37 6 157527695 157527695 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 37 136 0 ENST00000346085.5:c.5420G>A p.Gly1807Glu p.G1807E ENST00000346085 NM_020732.3 1807 gGg/gAg 0 +ARMC2 UCSF GRCh37 6 109294624 109294624 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 16 175 0 ENST00000392644.4:c.2511G>A p.Trp837Ter p.W837* ENST00000392644 NM_032131.4 837 tgG/tgA 0 +ARMC2 UCSF GRCh37 6 109190146 109190146 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 12 111 0 ENST00000392644.4:c.411G>A p.Arg137= p.R137= ENST00000392644 NM_032131.4 137 agG/agA 0 +ARMC4 UCSF GRCh37 10 28151470 28151470 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 20 137 0 ENST00000305242.5:c.2692C>T p.Leu898= p.L898= ENST00000305242 NM_018076.2 898 Ctg/Ttg 0 +ARMC6 UCSF GRCh37 19 19153577 19153577 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 32 224 0 ENST00000535612.1:c.87G>A p.Lys29= p.K29= ENST00000535612 NM_001199196.1 29 aaG/aaA 0 +ARMC8 UCSF GRCh37 3 138003305 138003305 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 24 228 0 ENST00000481646.1:c.1716G>A p.Gly572= p.G572= ENST00000481646 NM_015396.4 572 ggG/ggA 0 +ARMCX2 UCSF GRCh37 X 100910957 100910957 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 32 149 0 ENST00000328766.5:c.1618G>A p.Asp540Asn p.D540N ENST00000328766 NM_014782.5 540 Gat/Aat 0 +ARNT UCSF GRCh37 1 150786699 150786699 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 27 232 0 ENST00000358595.5:c.1967C>T p.Ala656Val p.A656V ENST00000358595 NM_178427.2 656 gCt/gTt 0 +ARPP19 UCSF GRCh37 15 52849334 52849334 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 19 114 0 ENST00000566423.1:c.131G>A p.Gly44Glu p.G44E ENST00000566423 44 gGa/gAa 0 +ARPP21 UCSF GRCh37 3 35785374 35785374 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 18 185 0 ENST00000458225.1:c.1952C>T p.Thr651Ile p.T651I ENST00000458225 651 aCc/aTc 0 +ARRB1 UCSF GRCh37 11 74985189 74985189 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 12 99 0 ENST00000420843.2:c.843C>T p.Asn281= p.N281= ENST00000420843 NM_004041.4 281 aaC/aaT 0 +ARRDC2 UCSF GRCh37 19 18112378 18112378 + downstream_gene_variant 3'Flank SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 7 62 0 ENST00000222249 NM_002248.4 0 +ARSJ UCSF GRCh37 4 114899759 114899759 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 17 184 0 ENST00000315366.7:c.232C>T p.Leu78Phe p.L78F ENST00000315366 NM_024590.3 78 Ctc/Ttc 0 +ARX UCSF GRCh37 X 25031293 25031293 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 42 142 0 ENST00000379044.4:c.819C>T p.Ala273= p.A273= ENST00000379044 NM_139058.2 273 gcC/gcT 0 +ASAP1 UCSF GRCh37 8 131073167 131073167 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 38 164 0 ENST00000357668.1:c.2850C>T p.Pro950= p.P950= ENST00000357668 950 ccC/ccT 0 +ASB10 UCSF GRCh37 7 150878373 150878373 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 208 30 199 0 ENST00000420175.2:c.757C>T p.Leu253= p.L253= ENST00000420175 253 Ctg/Ttg 0 +ASB16 UCSF GRCh37 17 42254374 42254374 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 29 0 ENST00000293414.1:c.838G>A p.Ala280Thr p.A280T ENST00000293414 NM_080863.4 280 Gcc/Acc 0 +ASH1L UCSF GRCh37 1 155451559 155451559 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 342 50 521 0 ENST00000392403.3:c.1102G>A p.Val368Ile p.V368I ENST00000392403 NM_018489.2 368 Gtt/Att 0 +ASH1L UCSF GRCh37 1 155448314 155448314 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 58 0 ENST00000392403.3:c.4347G>A p.Gln1449= p.Q1449= ENST00000392403 NM_018489.2 1449 caG/caA 0 +ASNSD1 UCSF GRCh37 2 190531191 190531191 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 161 30 250 0 ENST00000260952.4:c.333C>T p.Leu111= p.L111= ENST00000260952 NM_019048.2 111 ctC/ctT 0 +ASPG UCSF GRCh37 14 104569962 104569962 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 5 34 0 ENST00000551177.1:c.703G>A p.Glu235Lys p.E235K ENST00000551177 NM_001080464.2 235 Gag/Aag 0 +ASPH UCSF GRCh37 8 62438590 62438590 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 16 136 0 ENST00000379454.4:c.1846G>A p.Asp616Asn p.D616N ENST00000379454 NM_004318.3 616 Gat/Aat 0 +ASPM UCSF GRCh37 1 197071895 197071895 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 119 445 0 ENST00000367409.4:c.6486G>C p.Lys2162Asn p.K2162N ENST00000367409 NM_018136.4 2162 aaG/aaC 0 +ASTN2 UCSF GRCh37 9 119249637 119249637 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 3 41 0 ENST00000361209.2:c.3344+1G>A p.X1115_splice ENST00000361209 NM_014010.4 0 +ASTN2 UCSF GRCh37 9 119976908 119976908 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 16 143 0 ENST00000361209.2:c.744C>T p.Ala248= p.A248= ENST00000361209 NM_014010.4 248 gcC/gcT 0 +ASXL3 UCSF GRCh37 18 31324781 31324781 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 27 280 0 ENST00000269197.5:c.4969C>T p.Pro1657Ser p.P1657S ENST00000269197 NM_030632.1 1657 Ccc/Tcc 0 +ASXL3 UCSF GRCh37 18 31263528 31263528 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 18 128 0 ENST00000269197.5:c.875G>A p.Arg292Lys p.R292K ENST00000269197 NM_030632.1 292 aGg/aAg 0 +ATAD1 UCSF GRCh37 10 89552427 89552427 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 11 113 0 ENST00000308448.7:c.248C>T p.Pro83Leu p.P83L ENST00000308448 NM_032810.2 83 cCt/cTt 0 +ATAD2B UCSF GRCh37 2 23985174 23985174 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 344 53 428 0 ENST00000238789.5:c.3299G>A p.Gly1100Glu p.G1100E ENST00000238789 NM_001242338.1 1100 gGa/gAa 0 +ATF5 UCSF GRCh37 19 50436164 50436164 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 215 52 298 0 ENST00000423777.2:c.664G>A p.Ala222Thr p.A222T ENST00000423777 NM_001193646.1 222 Gct/Act 0 +ATP12A UCSF GRCh37 13 25266679 25266679 + missense_variant Missense_Mutation SNP G G A snp132_rs112162533 P24_Rec2 Untested WXS Illumina HiSeq 130 17 167 0 ENST00000218548.6:c.1199G>A p.Gly400Glu p.G400E ENST00000218548 NM_001185085.1 400 gGg/gAg 0 +ATP1A1 UCSF GRCh37 1 116930849 116930849 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 0 ENST00000537345.1:c.488del p.Asn163ThrfsTer9 p.N163Tfs*9 ENST00000537345 NM_001160233.1 162 Aaa/aa 0 +ATP1B2 UCSF GRCh37 17 7557516 7557516 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 293 44 330 0 ENST00000250111.4:c.493G>A p.Asp165Asn p.D165N ENST00000250111 NM_001678.3 165 Gac/Aac 0 +ATP5J2-PTCD1 UCSF GRCh37 7 99032499 99032499 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 11 109 0 ENST00000413834.1:c.514G>A p.Glu172Lys p.E172K ENST00000413834 172 Gaa/Aaa 0 +ATP6AP1 UCSF GRCh37 X 153662579 153662579 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 11 85 0 ENST00000369762.2:c.710C>T p.Ala237Val p.A237V ENST00000369762 NM_001183.4 237 gCc/gTc 0 +ATR UCSF GRCh37 3 142176554 142176554 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 235 37 351 0 ENST00000350721.4:c.7547C>T p.Thr2516Ile p.T2516I ENST00000350721 NM_001184.3 2516 aCt/aTt 0 +ATR UCSF GRCh37 3 142280101 142280101 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 163 24 274 0 ENST00000350721.4:c.1333C>T p.Pro445Ser p.P445S ENST00000350721 NM_001184.3 445 Cca/Tca 0 +ATRN UCSF GRCh37 20 3527970 3527970 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 13 150 0 ENST00000262919.5:c.777G>A p.Glu259= p.E259= ENST00000262919 NM_139321.2 259 gaG/gaA 0 +ATRNL1 UCSF GRCh37 10 116853739 116853739 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 56 150 0 ENST00000355044.3:c.230C>T p.Ser77Phe p.S77F ENST00000355044 NM_207303.2 77 tCc/tTc 0 +ATRX UCSF GRCh37 X 76939340 76939343 + frameshift_variant Frame_Shift_Del DEL CTAC CTAC - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 0 ENST00000373344.5:c.1405_1408delGTAG p.Val469IlefsTer44 p.V469Ifs*44 ENST00000373344 NM_000489.3 469 GTAGat/at 0 +ATXN10 UCSF GRCh37 22 46085607 46085607 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 10 4 26 0 ENST00000252934.5:c.132G>A p.Arg44= p.R44= ENST00000252934 NM_013236.3 44 agG/agA 0 +ATXN2 UCSF GRCh37 12 111956165 111956165 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 23 118 0 ENST00000377617.3:c.1533G>A p.Gln511= p.Q511= ENST00000377617 NM_002973.3 511 caG/caA 0 +ATXN7 UCSF GRCh37 3 63898902 63898902 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 192 35 291 0 ENST00000398590.3:c.394+1G>A p.X132_splice ENST00000398590 NM_001177387.1 0 +AUTS2 UCSF GRCh37 7 70255005 70255005 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 17 120 0 ENST00000342771.4:c.2803C>T p.Gln935Ter p.Q935* ENST00000342771 NM_015570.2 935 Cag/Tag 0 +AXIN1 UCSF GRCh37 16 360045 360045 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 10 84 0 ENST00000262320.3:c.1044C>T p.Ile348= p.I348= ENST00000262320 NM_003502.3 348 atC/atT 0 +B3GNT2 UCSF GRCh37 2 62449935 62449935 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 136 18 207 0 ENST00000301998.4:c.580C>T p.Leu194Phe p.L194F ENST00000301998 NM_006577.5 194 Ctt/Ttt 0 +B3GNT3 UCSF GRCh37 19 17922609 17922609 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 32 251 0 ENST00000318683.6:c.797C>T p.Pro266Leu p.P266L ENST00000318683 NM_014256.3 266 cCc/cTc 0 +B4GALT2 UCSF GRCh37 1 44447495 44447495 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 264 42 332 0 ENST00000309519.7:c.535C>T p.Pro179Ser p.P179S ENST00000309519 179 Ccc/Tcc 0 +B4GALT4 UCSF GRCh37 3 118948697 118948697 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 20 206 0 ENST00000483209.1:c.250C>T p.Leu84Phe p.L84F ENST00000483209 84 Ctc/Ttc 0 +B4GALT4 UCSF GRCh37 3 118942904 118942904 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 8 74 0 ENST00000483209.1:c.674+1G>A p.X225_splice ENST00000483209 0 +B4GALT6 UCSF GRCh37 18 29246326 29246326 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 41 356 0 ENST00000306851.5:c.125A>G p.Tyr42Cys p.Y42C ENST00000306851 NM_004775.3 42 tAt/tGt 0 +BAG5 UCSF GRCh37 14 104027253 104027253 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 25 264 0 ENST00000337322.4:c.372G>A p.Glu124= p.E124= ENST00000337322 NM_001015049.2 124 gaG/gaA 0 +BAIAP2 UCSF GRCh37 17 79089586 79089586 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 38 232 0 ENST00000321300.6:c.1552G>A p.Val518Ile p.V518I ENST00000321300 NM_001144888.1 518 Gtc/Atc 0 +BANF2 UCSF GRCh37 20 17716437 17716437 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 273 49 408 0 ENST00000545418.2:c.275G>A p.Trp92Ter p.W92* ENST00000545418 NM_001159495.1 92 tGg/tAg 0 +BAZ2A UCSF GRCh37 12 56992689 56992689 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 18 144 0 ENST00000551812.1:c.5515G>A p.Asp1839Asn p.D1839N ENST00000551812 NM_013449.3 1839 Gat/Aat 0 +BBS9 UCSF GRCh37 7 33573761 33573761 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 310 43 332 0 ENST00000242067.6:c.2494G>A p.Ala832Thr p.A832T ENST00000242067 NM_198428.2 832 Gca/Aca 0 +BCHE UCSF GRCh37 3 165547469 165547469 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 372 55 471 0 ENST00000264381.3:c.1353C>T p.His451= p.H451= ENST00000264381 NM_000055.2 451 caC/caT 0 +BCKDHB UCSF GRCh37 6 80838912 80838912 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 18 131 0 ENST00000320393.6:c.309C>T p.Val103= p.V103= ENST00000320393 NM_183050.2 103 gtC/gtT 0 +BCL7A UCSF GRCh37 12 122481940 122481940 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 19 67 0 ENST00000538010.1:c.420G>A p.Lys140= p.K140= ENST00000538010 NM_020993.3 140 aaG/aaA 0 +BCL9L UCSF GRCh37 11 118773773 118773773 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 9 66 0 ENST00000334801.3:c.760G>A p.Ala254Thr p.A254T ENST00000334801 NM_182557.2 254 Gca/Aca 0 +BDP1 UCSF GRCh37 5 70840967 70840967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 3 28 0 ENST00000358731.4:c.6665G>A p.Gly2222Asp p.G2222D ENST00000358731 NM_018429.2 2222 gGt/gAt 0 +BEND7 UCSF GRCh37 10 13481494 13481494 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 23 156 0 ENST00000341083.3:c.1085C>T p.Ala362Val p.A362V ENST00000341083 NM_152751.2 362 gCt/gTt 0 +BEST1 UCSF GRCh37 11 61730178 61730178 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 350 53 540 0 ENST00000449131.2:c.1372G>A p.Glu458Lys p.E458K ENST00000449131 NM_001139443.1 458 Gag/Aag 0 +BFAR UCSF GRCh37 16 14761652 14761652 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 34 175 0 ENST00000261658.2:c.1321G>A p.Glu441Lys p.E441K ENST00000261658 NM_016561.2 441 Gaa/Aaa 0 +BFSP2 UCSF GRCh37 3 133167362 133167362 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 8 51 0 ENST00000302334.2:c.602C>T p.Ala201Val p.A201V ENST00000302334 NM_003571.2 201 gCg/gTg 0 +BHLHE23 UCSF GRCh37 20 61637563 61637563 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 10 102 0 ENST00000370346.2:c.516G>A p.Gln172= p.Q172= ENST00000370346 NM_080606.3 172 caG/caA 0 +BIRC6 UCSF GRCh37 2 32656052 32656052 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 30 276 0 ENST00000421745.2:c.3142G>A p.Glu1048Lys p.E1048K ENST00000421745 NM_016252.3 1048 Gaa/Aaa 0 +BIRC6 UCSF GRCh37 2 32836611 32836611 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 8 60 0 ENST00000421745.2:c.14356G>A p.Val4786Ile p.V4786I ENST00000421745 NM_016252.3 4786 Gta/Ata 0 +BIRC6 UCSF GRCh37 2 32695362 32695362 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 17 229 0 ENST00000421745.2:c.6474G>A p.Arg2158= p.R2158= ENST00000421745 NM_016252.3 2158 agG/agA 0 +BLM UCSF GRCh37 15 91304351 91304351 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 22 217 0 ENST00000355112.3:c.1748C>T p.Ala583Val p.A583V ENST00000355112 NM_000057.2 583 gCc/gTc 0 +BMP5 UCSF GRCh37 6 55638867 55638867 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 10 75 0 ENST00000370830.3:c.1007C>T p.Ser336Phe p.S336F ENST00000370830 NM_021073.2 336 tCc/tTc 0 +BMP7 UCSF GRCh37 20 55841041 55841041 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 29 200 0 ENST00000395863.3:c.138C>T p.Leu46= p.L46= ENST00000395863 NM_001719.2 46 ctC/ctT 0 +BMPER UCSF GRCh37 7 34125541 34125541 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 92 296 0 ENST00000297161.2:c.1582G>A p.Val528Met p.V528M ENST00000297161 NM_133468.4 528 Gtg/Atg 0 +BNIPL UCSF GRCh37 1 151010133 151010133 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 11 68 0 ENST00000368931.3:c.132C>T p.Phe44= p.F44= ENST00000368931 NM_138278.3 44 ttC/ttT 0 +BOD1L UCSF GRCh37 4 13616314 13616314 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 17 205 0 ENST00000040738.5:c.680C>T p.Ala227Val p.A227V ENST00000040738 NM_148894.2 227 gCc/gTc 0 +BOD1L UCSF GRCh37 4 13597497 13597497 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 16 222 0 ENST00000040738.5:c.8091G>A p.Lys2697= p.K2697= ENST00000040738 NM_148894.2 2697 aaG/aaA 0 +BOLL UCSF GRCh37 2 198607882 198607882 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 60 0 ENST00000321801.7:c.767C>T p.Pro256Leu p.P256L ENST00000321801 NM_197970.2 256 cCt/cTt 0 +BRAP UCSF GRCh37 12 112087772 112087772 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 14 114 0 ENST00000419234.4:c.1386C>T p.Leu462= p.L462= ENST00000419234 NM_006768.3 462 ctC/ctT 0 +BRCA2 UCSF GRCh37 13 32921010 32921010 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 9 135 0 ENST00000380152.3:c.6984G>A p.Glu2328= p.E2328= ENST00000380152 2328 gaG/gaA 0 +BRD8 UCSF GRCh37 5 137497771 137497771 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 9 109 0 ENST00000254900.5:c.2152C>T p.Leu718Phe p.L718F ENST00000254900 NM_139199.1 718 Ctt/Ttt 0 +BRDT UCSF GRCh37 1 92470740 92470740 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 13 147 0 ENST00000362005.3:c.2659G>A p.Glu887Lys p.E887K ENST00000362005 NM_001242805.1 887 Gaa/Aaa 0 +BRE UCSF GRCh37 2 28460089 28460089 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 4 51 0 ENST00000344773.2:c.701C>T p.Ala234Val p.A234V ENST00000344773 NM_004899.4 234 gCt/gTt 0 +BRF1 UCSF GRCh37 14 105766903 105766903 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 11 50 0 ENST00000546474.1:c.64G>A p.Asp22Asn p.D22N ENST00000546474 NM_001519.3 22 Gac/Aac 0 +BRIP1 UCSF GRCh37 17 59761284 59761284 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 25 267 0 ENST00000259008.2:c.3123G>A p.Met1041Ile p.M1041I ENST00000259008 NM_032043.2 1041 atG/atA 0 +BRSK1 UCSF GRCh37 19 55798397 55798397 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 15 75 1 ENST00000309383.1:c.159C>T p.His53= p.H53= ENST00000309383 NM_032430.1 53 caC/caT 0 +BRSK2 UCSF GRCh37 11 1471823 1471823 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 6 93 0 ENST00000382179.1:c.1432C>T p.Pro478Ser p.P478S ENST00000382179 NM_001256630.1 478 Cct/Tct 0 +BSCL2 UCSF GRCh37 11 62457979 62457979 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 8 68 0 ENST00000433053.1:c.1249G>A p.Glu417Lys p.E417K ENST00000433053 417 Gaa/Aaa 0 +BTBD7 UCSF GRCh37 14 93727962 93727962 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 247 39 434 0 ENST00000334746.5:c.1433G>A p.Arg478Lys p.R478K ENST00000334746 NM_001002860.2 478 aGa/aAa 0 +BTN2A1 UCSF GRCh37 6 26465535 26465535 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 29 226 0 ENST00000312541.5:c.835C>T p.Leu279= p.L279= ENST00000312541 NM_007049.4 279 Ctg/Ttg 0 +BTN2A2 UCSF GRCh37 6 26384079 26384079 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 157 27 202 0 ENST00000356709.4:c.30C>T p.Ser10= p.S10= ENST00000356709 NM_001197240.1 10 tcC/tcT 0 +BTNL8 UCSF GRCh37 5 180376252 180376252 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 5 41 0 ENST00000340184.4:c.849C>T p.Ala283= p.A283= ENST00000340184 NM_001040462.2 283 gcC/gcT 0 +BTRC UCSF GRCh37 10 103310583 103310583 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 13 6 32 0 ENST00000370187.3:c.1784C>T p.Ser595Phe p.S595F ENST00000370187 NM_033637.3 595 tCc/tTc 0 +BZRAP1 UCSF GRCh37 17 56388331 56388331 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 7 96 0 ENST00000343736.4:c.3325C>T p.Pro1109Ser p.P1109S ENST00000343736 1109 Cct/Tct 0 +C10orf12 UCSF GRCh37 10 98743405 98743405 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 12 217 0 ENST00000286067.2:c.2258C>T p.Ala753Val p.A753V ENST00000286067 NM_015652.2 753 gCt/gTt 0 +C10orf12 UCSF GRCh37 10 98744660 98744660 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 4 94 0 ENST00000286067.2:c.3513G>A p.Arg1171= p.R1171= ENST00000286067 NM_015652.2 1171 agG/agA 0 +C10orf71 UCSF GRCh37 10 50534068 50534068 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 45 111 0 ENST00000374144.3:c.3478C>T p.Pro1160Ser p.P1160S ENST00000374144 1160 Cct/Tct 0 +C10orf71 UCSF GRCh37 10 50534110 50534110 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 8 99 0 ENST00000374144.3:c.3520C>T p.Pro1174Ser p.P1174S ENST00000374144 1174 Cca/Tca 0 +C10orf76 UCSF GRCh37 10 103753294 103753294 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 7 129 0 ENST00000370033.4:c.1275+1G>A p.X425_splice ENST00000370033 NM_024541.2 0 +C11orf24 UCSF GRCh37 11 68029451 68029451 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 26 186 0 ENST00000304271.6:c.1012C>T p.Pro338Ser p.P338S ENST00000304271 NM_022338.3 338 Cca/Tca 0 +C11orf35 UCSF GRCh37 11 557923 557923 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 7 33 0 ENST00000329451.3:c.516G>A p.Trp172Ter p.W172* ENST00000329451 NM_173573.2 172 tgG/tgA 0 +C12orf10 UCSF GRCh37 12 53696882 53696882 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 10 62 0 ENST00000267103.5:c.394G>A p.Ala132Thr p.A132T ENST00000267103 NM_021640.3 132 Gcg/Acg 0 +C12orf48 UCSF GRCh37 12 102542166 102542166 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 175 24 274 0 ENST00000358383.5:c.312G>A p.Met104Ile p.M104I ENST00000358383 104 atG/atA 0 +C12orf51 UCSF GRCh37 12 112623136 112623136 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 8 47 0 ENST00000550722.1:c.9196C>T p.Leu3066= p.L3066= ENST00000550722 NM_001109662.3 3066 Ctg/Ttg 0 +C12orf68 UCSF GRCh37 12 48578225 48578225 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 33 196 0 ENST00000316554.3:c.320G>A p.Gly107Asp p.G107D ENST00000316554 NM_001013635.3 107 gGc/gAc 0 +C13orf16 UCSF GRCh37 13 111995112 111995112 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 30 221 0 ENST00000283547.1:c.249G>A p.Gln83= p.Q83= ENST00000283547 NM_152324.1 83 caG/caA 0 +C14orf182 UCSF GRCh37 14 50472417 50472417 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 287 41 452 0 ENST00000399206.1:c.101C>T p.Ala34Val p.A34V ENST00000399206 NM_001012706.1 34 gCc/gTc 0 +C14orf183 UCSF GRCh37 14 50558446 50558446 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 14 165 0 ENST00000305273.1:c.122C>T p.Pro41Leu p.P41L ENST00000305273 NM_001014830.1 41 cCc/cTc 0 +C14orf37 UCSF GRCh37 14 58604864 58604864 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 25 215 0 ENST00000267485.7:c.1213G>A p.Glu405Lys p.E405K ENST00000267485 NM_001001872.2 405 Gaa/Aaa 0 +C15orf33 UCSF GRCh37 15 49907317 49907317 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 33 263 0 ENST00000299338.6:c.51+1G>A p.X17_splice ENST00000299338 NM_152647.2 0 +C15orf42 UCSF GRCh37 15 90150057 90150057 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 19 197 0 ENST00000268138.7:c.2722+1G>A p.X908_splice ENST00000268138 0 +C15orf59 UCSF GRCh37 15 74032417 74032417 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 12 144 0 ENST00000569673.1:c.723G>A p.Arg241= p.R241= ENST00000569673 241 cgG/cgA 0 +C17orf101 UCSF GRCh37 17 80373362 80373362 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 248 53 363 0 ENST00000329197.5:c.216G>A p.Glu72= p.E72= ENST00000329197 72 gaG/gaA 0 +C17orf39 UCSF GRCh37 17 17943049 17943049 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 4 45 0 ENST00000268719.4:c.271C>T p.Pro91Ser p.P91S ENST00000268719 NM_024052.4 91 Ccc/Tcc 0 +C17orf47 UCSF GRCh37 17 56621224 56621224 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 111 400 0 ENST00000321691.3:c.324G>A p.Lys108= p.K108= ENST00000321691 NM_001038704.2 108 aaG/aaA 0 +C17orf51 UCSF GRCh37 17 21454409 21454409 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 14 95 0 ENST00000391411.5:c.277C>T p.Leu93= p.L93= ENST00000391411 NM_001113434.3 93 Ctg/Ttg 0 +C17orf53 UCSF GRCh37 17 42225701 42225701 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 9 87 0 ENST00000319977.4:c.530G>A p.Gly177Glu p.G177E ENST00000319977 NM_024032.3 177 gGa/gAa 0 +C17orf75 UCSF GRCh37 17 30662460 30662460 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 29 203 1 ENST00000577809.1:c.551C>T p.Ala184Val p.A184V ENST00000577809 NM_022344.3 184 gCa/gTa 0 +C17orf80 UCSF GRCh37 17 71232924 71232924 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 249 35 320 0 ENST00000359042.2:c.1303G>A p.Ala435Thr p.A435T ENST00000359042 NM_017941.4 435 Gcc/Acc 0 +C17orf97 UCSF GRCh37 17 263205 263205 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 30 180 0 ENST00000360127.6:c.571C>T p.Leu191= p.L191= ENST00000360127 NM_001013672.4 191 Ctg/Ttg 0 +C18orf8 UCSF GRCh37 18 21098917 21098917 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 13 44 0 ENST00000269221.3:c.717G>A p.Ala239= p.A239= ENST00000269221 NM_013326.4 239 gcG/gcA 0 +C19orf29 UCSF GRCh37 19 3623943 3623943 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 193 70 208 0 ENST00000429344.2:c.385G>A p.Ala129Thr p.A129T ENST00000429344 NM_001080543.1 129 Gcg/Acg 0 +C19orf29 UCSF GRCh37 19 3623985 3623985 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 12 112 0 ENST00000429344.2:c.343G>A p.Ala115Thr p.A115T ENST00000429344 NM_001080543.1 115 Gca/Aca 0 +C19orf29 UCSF GRCh37 19 3613530 3613530 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 136 17 145 0 ENST00000429344.2:c.1410G>A p.Gln470= p.Q470= ENST00000429344 NM_001080543.1 470 caG/caA 0 +C1orf106 UCSF GRCh37 1 200876961 200876961 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 4 23 0 ENST00000413687.2:c.521-1G>A p.X174_splice ENST00000413687 NM_001142569.2 0 +C1orf127 UCSF GRCh37 1 11007896 11007896 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 12 101 0 ENST00000377004.4:c.2296C>T p.Pro766Ser p.P766S ENST00000377004 NM_001170754.1 766 Ccc/Tcc 0 +C1orf141 UCSF GRCh37 1 67592920 67592920 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 328 54 571 1 ENST00000371007.2:c.4G>A p.Ala2Thr p.A2T ENST00000371007 2 Gca/Aca 0 +C1orf173 UCSF GRCh37 1 75055443 75055443 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 32 299 0 ENST00000326665.5:c.2048G>A p.Gly683Asp p.G683D ENST00000326665 NM_001002912.4 683 gGt/gAt 0 +C1orf63 UCSF GRCh37 1 25573350 25573350 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 26 190 0 ENST00000243189.7:c.105G>A p.Arg35= p.R35= ENST00000243189 NM_020317.3 35 agG/agA 0 +C1orf65 UCSF GRCh37 1 223568113 223568113 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 4 17 0 ENST00000366875.3:c.1296C>T p.Ala432= p.A432= ENST00000366875 NM_152610.2 432 gcC/gcT 0 +C1S UCSF GRCh37 12 7173913 7173913 + synonymous_variant Silent SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 23 126 0 ENST00000406697.1:c.963T>C p.Cys321= p.C321= ENST00000406697 321 tgT/tgC 0 +C2 UCSF GRCh37 6 31905227 31905227 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 5 35 0 ENST00000299367.5:c.1120C>T p.Leu374= p.L374= ENST00000299367 NM_000063.4 374 Ctg/Ttg 0 +C20orf132 UCSF GRCh37 20 35788532 35788532 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 284 46 412 0 ENST00000343811.4:c.776C>T p.Arg259= p.R259= ENST00000343811 NM_152503.4 259 cgC/cgT 0 +C20orf177 UCSF GRCh37 20 58519916 58519916 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 13 160 0 ENST00000358293.3:c.918G>A p.Trp306Ter p.W306* ENST00000358293 NM_001190826.1 306 tgG/tgA 0 +C20orf3 UCSF GRCh37 20 24950902 24950902 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 32 251 0 ENST00000217456.2:c.644C>T p.Thr215Ile p.T215I ENST00000217456 NM_020531.2 215 aCc/aTc 0 +C22orf29 UCSF GRCh37 22 19839202 19839202 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 22 241 0 ENST00000405640.1:c.583C>T p.Pro195Ser p.P195S ENST00000405640 195 Ccc/Tcc 0 +C2orf15 UCSF GRCh37 2 99766983 99766983 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 19 180 0 ENST00000302513.2:c.64G>A p.Val22Ile p.V22I ENST00000302513 NM_144706.2 22 Gta/Ata 0 +C2orf16 UCSF GRCh37 2 27802966 27802966 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 217 28 342 1 ENST00000408964.2:c.3527C>T p.Ser1176Phe p.S1176F ENST00000408964 NM_032266.3 1176 tCc/tTc 0 +C2orf16 UCSF GRCh37 2 27802761 27802761 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 379 67 584 0 ENST00000408964.2:c.3322C>T p.Pro1108Ser p.P1108S ENST00000408964 NM_032266.3 1108 Cca/Tca 0 +C2orf28 UCSF GRCh37 2 27439390 27439390 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 16 154 0 ENST00000380171.3:c.653-1G>A p.X218_splice ENST00000380171 NM_080592.3 0 +C2orf29 UCSF GRCh37 2 101869740 101869740 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 11 143 0 ENST00000289382.3:c.314G>A p.Gly105Asp p.G105D ENST00000289382 NM_017546.4 105 gGc/gAc 0 +C2orf65 UCSF GRCh37 2 74785967 74785967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 285 52 380 0 ENST00000290536.5:c.1469C>T p.Thr490Ile p.T490I ENST00000290536 NM_138804.4 490 aCt/aTt 0 +C3orf17 UCSF GRCh37 3 112730247 112730247 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 37 256 0 ENST00000314400.5:c.558C>T p.Leu186= p.L186= ENST00000314400 NM_015412.3 186 ctC/ctT 0 +C3orf25 UCSF GRCh37 3 129120583 129120583 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 28 0 ENST00000505956.1:c.1572C>T p.Asp524= p.D524= ENST00000505956 NM_207307.1 524 gaC/gaT 0 +C3orf58 UCSF GRCh37 3 143708377 143708377 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 17 185 0 ENST00000315691.3:c.987G>A p.Trp329Ter p.W329* ENST00000315691 NM_173552.3 329 tgG/tgA 0 +C3orf77 UCSF GRCh37 3 44310793 44310793 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 14 115 0 ENST00000309765.4:c.3246G>A p.Gly1082= p.G1082= ENST00000309765 NM_001145030.1 1082 ggG/ggA 0 +C4BPB UCSF GRCh37 1 207271536 207271536 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 21 202 0 ENST00000243611.5:c.545G>A p.Gly182Glu p.G182E ENST00000243611 NM_000716.3 182 gGg/gAg 0 +C4orf14 UCSF GRCh37 4 57843376 57843376 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 39 219 0 ENST00000264230.4:c.376G>A p.Val126Ile p.V126I ENST00000264230 NM_032313.2 126 Gtc/Atc 0 +C4orf17 UCSF GRCh37 4 100443827 100443827 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 10 42 0 ENST00000326581.4:c.298G>A p.Ala100Thr p.A100T ENST00000326581 NM_032149.2 100 Gcc/Acc 0 +C4orf21 UCSF GRCh37 4 113538832 113538832 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 342 48 507 0 ENST00000505019.1:c.2366G>A p.Gly789Glu p.G789E ENST00000505019 NM_018392.4 789 gGa/gAa 0 +C5orf34 UCSF GRCh37 5 43503809 43503809 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 228 26 317 0 ENST00000306862.2:c.986C>T p.Pro329Leu p.P329L ENST00000306862 NM_198566.2 329 cCt/cTt 0 +C5orf35 UCSF GRCh37 5 56205488 56205488 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 18 144 0 ENST00000285947.2:c.16C>T p.Leu6= p.L6= ENST00000285947 NM_153706.3 6 Ctg/Ttg 0 +C5orf42 UCSF GRCh37 5 37244646 37244646 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 58 220 0 ENST00000425232.2:c.401C>T p.Pro134Leu p.P134L ENST00000425232 NM_023073.3 134 cCt/cTt 0 +C5orf54 UCSF GRCh37 5 159820941 159820941 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 293 47 412 0 ENST00000408953.3:c.1557C>T p.Ala519= p.A519= ENST00000408953 NM_022090.3 519 gcC/gcT 0 +C6orf106 UCSF GRCh37 6 34664256 34664256 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 77 1 ENST00000374023.3:c.125C>T p.Ala42Val p.A42V ENST00000374023 NM_024294.2 42 gCc/gTc 0 +C6orf203 UCSF GRCh37 6 107372309 107372309 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 7 59 0 ENST00000443043.1:c.607G>A p.Ala203Thr p.A203T ENST00000443043 NM_001142470.1 203 Gca/Aca 0 +C6orf25 UCSF GRCh37 6 31691969 31691969 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 39 296 0 ENST00000375806.2:c.460C>T p.Leu154Phe p.L154F ENST00000375806 154 Ctc/Ttc 0 +C6orf27 UCSF GRCh37 6 31737510 31737510 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 14 51 0 ENST00000375688.4:c.1259C>T p.Pro420Leu p.P420L ENST00000375688 420 cCc/cTc 0 +C7orf36 UCSF GRCh37 7 39612265 39612265 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 16 195 0 ENST00000223273.2:c.641G>A p.Gly214Asp p.G214D ENST00000223273 NM_020192.3 214 gGc/gAc 0 +C7orf47 UCSF GRCh37 7 100032988 100032988 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 11 93 0 ENST00000292330.2:c.757G>A p.Ala253Thr p.A253T ENST00000292330 NM_145030.2 253 Gcg/Acg 0 +C7orf70 UCSF GRCh37 7 6370050 6370050 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 18 117 0 ENST00000313324.4:c.736G>A p.Ala246Thr p.A246T ENST00000313324 NM_001037163.1 246 Gct/Act 0 +C9orf139 UCSF GRCh37 9 139929283 139929283 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 199 34 237 0 ENST00000314330.2:c.350C>T p.Pro117Leu p.P117L ENST00000314330 NM_207511.1 117 cCc/cTc 0 +C9orf140 UCSF GRCh37 9 139960809 139960809 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 15 123 0 ENST00000409687.3:c.589G>A p.Ala197Thr p.A197T ENST00000409687 NM_178448.3 197 Gcc/Acc 0 +C9orf156 UCSF GRCh37 9 100672771 100672771 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 13 136 0 ENST00000375119.3:c.537G>A p.Gln179= p.Q179= ENST00000375119 NM_016481.3 179 caG/caA 0 +C9orf169 UCSF GRCh37 9 140120399 140120399 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 11 138 0 ENST00000359069.2:c.326G>A p.Gly109Glu p.G109E ENST00000359069 NM_199001.2 109 gGg/gAg 0 +C9orf47 UCSF GRCh37 9 91606069 91606069 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 15 127 0 ENST00000334490.5:c.159C>T p.Phe53= p.F53= ENST00000334490 53 ttC/ttT 0 +C9orf68 UCSF GRCh37 9 4622455 4622455 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 14 88 0 ENST00000475086.1:c.551C>T p.Ser184Phe p.S184F ENST00000475086 NM_001039395.3 184 tCt/tTt 0 +C9orf86 UCSF GRCh37 9 139731824 139731824 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 3 25 0 ENST00000371663.4:c.839G>A p.Ser280Asn p.S280N ENST00000371663 NM_001173988.1 280 aGc/aAc 0 +CABIN1 UCSF GRCh37 22 24456476 24456476 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 144 28 195 0 ENST00000398319.2:c.1489C>T p.His497Tyr p.H497Y ENST00000398319 NM_001199281.1 497 Cac/Tac 0 +CACHD1 UCSF GRCh37 1 65117844 65117844 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 19 149 0 ENST00000290039.5:c.1238G>A p.Gly413Asp p.G413D ENST00000290039 NM_020925.2 413 gGt/gAt 0 +CACNA1A UCSF GRCh37 19 13340982 13340982 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 14 99 0 ENST00000360228.5:c.5442G>A p.Glu1814= p.E1814= ENST00000360228 NM_001127222.1 1814 gaG/gaA 0 +CACNA1E UCSF GRCh37 1 181701955 181701955 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 8 84 0 ENST00000367573.2:c.2733G>A p.Arg911= p.R911= ENST00000367573 NM_001205293.1 911 cgG/cgA 0 +CACNA1F UCSF GRCh37 X 49063214 49063214 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 78 0 ENST00000376265.2:c.5367C>T p.Arg1789= p.R1789= ENST00000376265 NM_005183.2 1789 cgC/cgT 0 +CACNA2D2 UCSF GRCh37 3 50425020 50425020 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 7 63 1 ENST00000479441.1:c.489C>T p.Asp163= p.D163= ENST00000479441 163 gaC/gaT 0 +CACNA2D4 UCSF GRCh37 12 1969357 1969357 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 29 234 0 ENST00000382722.5:c.1894C>T p.Leu632= p.L632= ENST00000382722 NM_172364.4 632 Ctg/Ttg 0 +CACNB4 UCSF GRCh37 2 152698533 152698533 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 212 38 307 0 ENST00000539935.1:c.1186G>A p.Glu396Lys p.E396K ENST00000539935 NM_001145798.1 396 Gag/Aag 0 +CAD UCSF GRCh37 2 27448004 27448004 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 85 191 0 ENST00000264705.4:c.1513C>T p.Pro505Ser p.P505S ENST00000264705 NM_004341.3 505 Cca/Tca 0 +CALCR UCSF GRCh37 7 93067438 93067438 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 11 112 0 ENST00000359558.2:c.966C>T p.Asn322= p.N322= ENST00000359558 NM_001164737.1 322 aaC/aaT 0 +CALCRL UCSF GRCh37 2 188217005 188217005 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 23 228 0 ENST00000409998.1:c.964G>A p.Val322Ile p.V322I ENST00000409998 322 Gtt/Att 0 +CALD1 UCSF GRCh37 7 134625943 134625943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 26 97 0 ENST00000361675.2:c.1487G>A p.Gly496Glu p.G496E ENST00000361675 496 gGa/gAa 0 +CALR3 UCSF GRCh37 19 16596053 16596053 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 31 233 0 ENST00000269881.3:c.413G>A p.Gly138Glu p.G138E ENST00000269881 NM_145046.4 138 gGa/gAa 0 +CAMKK1 UCSF GRCh37 17 3785649 3785649 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 26 160 0 ENST00000158166.5:c.701C>T p.Ala234Val p.A234V ENST00000158166 NM_172207.2 234 gCc/gTc 0 +CAND2 UCSF GRCh37 3 12854500 12854500 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 8 85 0 ENST00000456430.2:c.769G>A p.Asp257Asn p.D257N ENST00000456430 NM_001162499.1 257 Gac/Aac 0 +CAPG UCSF GRCh37 2 85628372 85628372 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 15 172 0 ENST00000263867.4:c.432G>A p.Gly144= p.G144= ENST00000263867 NM_001256140.1 144 ggG/ggA 0 +CAPN1 UCSF GRCh37 11 64951005 64951005 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 22 131 0 ENST00000527323.1:c.398G>A p.Arg133Gln p.R133Q ENST00000527323 133 cGa/cAa 0 +CARD10 UCSF GRCh37 22 37902215 37902215 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 18 0 ENST00000403299.1:c.1367G>A p.Gly456Asp p.G456D ENST00000403299 456 gGt/gAt 0 +CARD10 UCSF GRCh37 22 37903890 37903890 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 18 115 0 ENST00000403299.1:c.1137C>T p.His379= p.H379= ENST00000403299 379 caC/caT 0 +CARD14 UCSF GRCh37 17 78165266 78165266 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 52 0 ENST00000573882.1:c.1234G>A p.Gly412Ser p.G412S ENST00000573882 412 Ggt/Agt 0 +CARD14 UCSF GRCh37 17 78166319 78166319 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 6 46 0 ENST00000573882.1:c.1257G>A p.Arg419= p.R419= ENST00000573882 419 agG/agA 0 +CARD8 UCSF GRCh37 19 48733713 48733713 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 25 239 0 ENST00000391898.3:c.1017C>T p.Ser339= p.S339= ENST00000391898 NM_001184900.1 339 agC/agT 0 +CARD8 UCSF GRCh37 19 48734242 48734242 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 4 63 0 ENST00000391898.3:c.564C>T p.Gly188= p.G188= ENST00000391898 NM_001184900.1 188 ggC/ggT 0 +CARM1 UCSF GRCh37 19 11022892 11022892 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 401 151 508 0 ENST00000327064.4:c.591C>T p.Ile197= p.I197= ENST00000327064 NM_199141.1 197 atC/atT 0 +CARS UCSF GRCh37 11 3028116 3028116 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 16 193 0 ENST00000380525.4:c.2142C>T p.Asp714= p.D714= ENST00000380525 NM_001194997.1 714 gaC/gaT 0 +CASKIN1 UCSF GRCh37 16 2230836 2230836 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 51 0 ENST00000343516.6:c.2533G>A p.Gly845Arg p.G845R ENST00000343516 NM_020764.3 845 Ggg/Agg 0 +CASKIN2 UCSF GRCh37 17 73498124 73498124 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 17 111 0 ENST00000321617.3:c.3031G>A p.Val1011Met p.V1011M ENST00000321617 NM_020753.4 1011 Gtg/Atg 0 +CASKIN2 UCSF GRCh37 17 73509868 73509868 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 214 47 296 0 ENST00000321617.3:c.18C>T p.Asp6= p.D6= ENST00000321617 NM_020753.4 6 gaC/gaT 0 +CASP1 UCSF GRCh37 11 104897673 104897673 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 20 165 0 ENST00000533400.1:c.1012G>A p.Val338Ile p.V338I ENST00000533400 NM_001257118.1 338 Gtt/Att 0 +CASP8AP2 UCSF GRCh37 6 90562942 90562942 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 33 241 0 ENST00000551025.1:n.1550G>A *517* ENST00000551025 0 +CBFA2T2 UCSF GRCh37 20 32212628 32212628 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 41 305 0 ENST00000346541.3:c.778G>A p.Val260Ile p.V260I ENST00000346541 NM_005093.3 260 Gta/Ata 0 +CBL UCSF GRCh37 11 119145623 119145623 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 12 104 0 ENST00000264033.4:c.829G>A p.Val277Met p.V277M ENST00000264033 NM_005188.3 277 Gtg/Atg 0 +CBX2 UCSF GRCh37 17 77758206 77758206 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 18 141 0 ENST00000310942.4:c.964G>A p.Gly322Arg p.G322R ENST00000310942 NM_005189.2 322 Ggg/Agg 0 +CBX6 UCSF GRCh37 22 39262663 39262663 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 13 59 0 ENST00000407418.3:c.790C>T p.Pro264Ser p.P264S ENST00000407418 264 Ccc/Tcc 0 +CCBE1 UCSF GRCh37 18 57107014 57107014 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 6 37 0 ENST00000439986.4:c.810C>T p.Pro270= p.P270= ENST00000439986 NM_133459.3 270 ccC/ccT 0 +CCDC108 UCSF GRCh37 2 219903674 219903674 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 9 70 0 ENST00000341552.5:c.97C>T p.Leu33Phe p.L33F ENST00000341552 NM_194302.3 33 Ctc/Ttc 0 +CCDC112 UCSF GRCh37 5 114612683 114612683 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 9 80 0 ENST00000379611.5:c.430G>A p.Asp144Asn p.D144N ENST00000379611 NM_001040440.2 144 Gat/Aat 0 +CCDC113 UCSF GRCh37 16 58312424 58312424 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 7 36 0 ENST00000219299.4:c.930G>A p.Arg310= p.R310= ENST00000219299 NM_014157.3 310 cgG/cgA 0 +CCDC13 UCSF GRCh37 3 42798628 42798628 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 263 35 374 0 ENST00000310232.6:c.300G>A p.Leu100= p.L100= ENST00000310232 NM_144719.3 100 ctG/ctA 0 +CCDC157 UCSF GRCh37 22 30771592 30771592 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 21 115 0 ENST00000405659.1:c.1797C>T p.Asn599= p.N599= ENST00000405659 599 aaC/aaT 0 +CCDC158 UCSF GRCh37 4 77288491 77288491 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 12 141 0 ENST00000388914.3:c.1786G>A p.Glu596Lys p.E596K ENST00000388914 NM_001042784.1 596 Gag/Aag 0 +CCDC169 UCSF GRCh37 13 36869981 36869981 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 30 282 0 ENST00000503173.1:c.97C>T p.Leu33Phe p.L33F ENST00000503173 NM_001198908.1 33 Ctc/Ttc 0 +CCDC28A UCSF GRCh37 6 139100982 139100982 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 7 55 0 ENST00000332797.6:c.452C>T p.Pro151Leu p.P151L ENST00000332797 NM_015439.2 151 cCt/cTt 0 +CCDC42B UCSF GRCh37 12 113592333 113592333 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 3 19 0 ENST00000335621.6:c.583C>T p.Leu195= p.L195= ENST00000335621 NM_001144872.1 195 Ctg/Ttg 0 +CCDC48 UCSF GRCh37 3 128758672 128758672 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 337 38 446 0 ENST00000480450.1:c.1778C>T p.Pro593Leu p.P593L ENST00000480450 593 cCc/cTc 0 +CCDC67 UCSF GRCh37 11 93127823 93127823 + splice_donor_variant Splice_Site SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 4 34 0 ENST00000298050.3:c.1239+1G>T p.X413_splice ENST00000298050 NM_181645.3 0 +CCDC70 UCSF GRCh37 13 52440126 52440126 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 11 140 0 ENST00000242819.4:c.612C>T p.Gly204= p.G204= ENST00000242819 NM_031290.2 204 ggC/ggT 0 +CCDC80 UCSF GRCh37 3 112358176 112358176 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 29 203 0 ENST00000206423.3:c.577G>A p.Ala193Thr p.A193T ENST00000206423 NM_199512.1 193 Gca/Aca 0 +CCDC87 UCSF GRCh37 11 66360341 66360341 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 43 133 0 ENST00000333861.3:c.146C>T p.Pro49Leu p.P49L ENST00000333861 NM_018219.2 49 cCt/cTt 0 +CCDC88B UCSF GRCh37 11 64117117 64117117 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 6 42 0 ENST00000356786.5:c.2839C>T p.Gln947Ter p.Q947* ENST00000356786 NM_032251.5 947 Cag/Tag 0 +CCDC88B UCSF GRCh37 11 64111020 64111020 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 43 296 0 ENST00000356786.5:c.1251G>A p.Glu417= p.E417= ENST00000356786 NM_032251.5 417 gaG/gaA 0 +CCDC96 UCSF GRCh37 4 7044063 7044063 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 708 115 847 1 ENST00000310085.4:c.603C>T p.Leu201= p.L201= ENST00000310085 NM_153376.2 201 ctC/ctT 0 +CCKBR UCSF GRCh37 11 6281250 6281250 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 5 57 0 ENST00000334619.2:c.92G>A p.Ser31Asn p.S31N ENST00000334619 NM_176875.3 31 aGc/aAc 0 +CCNE1 UCSF GRCh37 19 30313252 30313252 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 27 276 0 ENST00000262643.3:c.946G>A p.Val316Ile p.V316I ENST00000262643 NM_001238.2 316 Gtt/Att 0 +CCPG1 UCSF GRCh37 15 55669234 55669234 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 46 154 0 ENST00000442196.3:c.367G>A p.Val123Ile p.V123I ENST00000442196 123 Gtc/Atc 0 +CCPG1 UCSF GRCh37 15 55652252 55652252 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 233 31 398 0 ENST00000442196.3:c.1719G>A p.Gln573= p.Q573= ENST00000442196 573 caG/caA 0 +CCR4 UCSF GRCh37 3 32994996 32994996 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 22 196 0 ENST00000330953.5:c.82C>T p.Pro28Ser p.P28S ENST00000330953 NM_005508.4 28 Cct/Tct 0 +CCT7 UCSF GRCh37 2 73470250 73470250 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 404 73 563 0 ENST00000258091.5:c.386C>T p.Thr129Ile p.T129I ENST00000258091 NM_006429.3 129 aCc/aTc 0 +CCT7 UCSF GRCh37 2 73471671 73471671 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 13 132 0 ENST00000258091.5:c.447-1G>A p.X149_splice ENST00000258091 NM_006429.3 0 +CD101 UCSF GRCh37 1 117559842 117559842 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 10 67 0 ENST00000256652.4:c.1359C>T p.Asp453= p.D453= ENST00000256652 NM_004258.5 453 gaC/gaT 0 +CD19 UCSF GRCh37 16 28946795 28946795 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 26 239 0 ENST00000538922.1:c.866G>A p.Gly289Asp p.G289D ENST00000538922 NM_001178098.1 289 gGc/gAc 0 +CD1E UCSF GRCh37 1 158325748 158325748 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 4 57 0 ENST00000368167.3:c.757G>A p.Gly253Ser p.G253S ENST00000368167 NM_030893.3 253 Ggc/Agc 0 +CD22 UCSF GRCh37 19 35837562 35837562 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 17 195 0 ENST00000085219.5:c.2506G>A p.Ala836Thr p.A836T ENST00000085219 NM_001771.3 836 Gca/Aca 0 +CD248 UCSF GRCh37 11 66084293 66084293 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 5 38 1 ENST00000311330.3:c.206G>A p.Arg69His p.R69H ENST00000311330 NM_020404.2 69 cGt/cAt 0 +CD300LB UCSF GRCh37 17 72522017 72522017 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 369 47 545 0 ENST00000392621.1:c.351C>T p.Asp117= p.D117= ENST00000392621 NM_174892.3 117 gaC/gaT 0 +CD300LG UCSF GRCh37 17 41932684 41932684 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 30 248 0 ENST00000317310.4:c.829G>A p.Glu277Lys p.E277K ENST00000317310 NM_145273.3 277 Gaa/Aaa 0 +CD79B UCSF GRCh37 17 62009612 62009612 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 39 0 ENST00000392795.3:c.10C>T p.Leu4= p.L4= ENST00000392795 NM_001039933.1 4 Ctg/Ttg 0 +CD82 UCSF GRCh37 11 44640662 44640662 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 72 468 0 ENST00000227155.4:c.790G>A p.Val264Ile p.V264I ENST00000227155 NM_002231.3 264 Gtc/Atc 0 +CD86 UCSF GRCh37 3 121838324 121838324 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 14 74 0 ENST00000330540.2:c.933G>A p.Gln311= p.Q311= ENST00000330540 NM_175862.4 311 caG/caA 0 +CDADC1 UCSF GRCh37 13 49822220 49822220 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 5 24 0 ENST00000251108.6:c.47G>A p.Gly16Glu p.G16E ENST00000251108 NM_001193478.1 16 gGg/gAg 0 +CDAN1 UCSF GRCh37 15 43017755 43017755 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 17 112 0 ENST00000356231.3:c.3382C>T p.Pro1128Ser p.P1128S ENST00000356231 NM_138477.2 1128 Ccg/Tcg 0 +CDAN1 UCSF GRCh37 15 43028098 43028098 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 37 232 0 ENST00000356231.3:c.748G>A p.Glu250Lys p.E250K ENST00000356231 NM_138477.2 250 Gag/Aag 0 +CDC14A UCSF GRCh37 1 100889822 100889822 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 351 58 561 0 ENST00000361544.6:c.354C>T p.Leu118= p.L118= ENST00000361544 NM_033312.2 118 ctC/ctT 0 +CDC42BPA UCSF GRCh37 1 227219128 227219128 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 255 43 401 0 ENST00000366769.3:c.3541G>A p.Gly1181Arg p.G1181R ENST00000366769 NM_003607.3 1181 Gga/Aga 0 +CDC42BPA UCSF GRCh37 1 227300117 227300117 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 22 235 0 ENST00000366769.3:c.1897G>A p.Val633Ile p.V633I ENST00000366769 NM_003607.3 633 Gtt/Att 0 +CDC42EP4 UCSF GRCh37 17 71281979 71281979 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 29 226 0 ENST00000335793.3:c.661G>A p.Val221Ile p.V221I ENST00000335793 221 Gtc/Atc 0 +CDC5L UCSF GRCh37 6 44360425 44360425 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 8 45 0 ENST00000371477.3:c.171C>T p.Ser57= p.S57= ENST00000371477 NM_001253.3 57 agC/agT 0 +CDC6 UCSF GRCh37 17 38447468 38447468 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 93 354 0 ENST00000209728.4:c.337G>A p.Ala113Thr p.A113T ENST00000209728 NM_001254.3 113 Gcc/Acc 0 +CDCA7L UCSF GRCh37 7 21947778 21947778 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 6 35 0 ENST00000406877.3:c.651G>A p.Arg217= p.R217= ENST00000406877 NM_018719.4 217 agG/agA 0 +CDH11 UCSF GRCh37 16 64984895 64984895 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 84 0 ENST00000268603.4:c.1669C>T p.Arg557Cys p.R557C ENST00000268603 NM_001797.2 557 Cgt/Tgt 0 +CDH23 UCSF GRCh37 10 73437447 73437447 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 7 8 35 0 ENST00000224721.6:c.1764C>T p.Leu588= p.L588= ENST00000224721 NM_022124.5 588 ctC/ctT 0 +CDH6 UCSF GRCh37 5 31302331 31302331 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 10 93 0 ENST00000265071.2:c.925G>A p.Asp309Asn p.D309N ENST00000265071 NM_004932.3 309 Gac/Aac 0 +CDH7 UCSF GRCh37 18 63477089 63477089 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 8 103 0 ENST00000397968.2:c.360C>T p.Leu120= p.L120= ENST00000397968 NM_004361.2 120 ctC/ctT 0 +CDHR5 UCSF GRCh37 11 618993 618993 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 11 61 0 ENST00000358353.3:c.1566G>A p.Pro522= p.P522= ENST00000358353 522 ccG/ccA 0 +CDK19 UCSF GRCh37 6 110953334 110953334 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 27 359 0 ENST00000368911.3:c.545C>T p.Ser182Phe p.S182F ENST00000368911 NM_015076.3 182 tCt/tTt 0 +CDK6 UCSF GRCh37 7 92247402 92247402 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 78 11 106 0 ENST00000265734.4:c.818G>A p.Gly273Asp p.G273D ENST00000265734 NM_001259.6 273 gGc/gAc 0 +CDKL3 UCSF GRCh37 5 133695755 133695755 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 7 42 0 ENST00000265334.4:c.193C>T p.Leu65= p.L65= ENST00000265334 NM_001113575.1 65 Ctg/Ttg 0 +CDKL4 UCSF GRCh37 2 39456661 39456661 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 47 439 0 ENST00000378803.1:c.13G>A p.Glu5Lys p.E5K ENST00000378803 NM_001009565.1 5 Gaa/Aaa 0 +CDS2 UCSF GRCh37 20 5157294 5157294 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 19 163 0 ENST00000460006.1:c.292G>A p.Val98Met p.V98M ENST00000460006 NM_003818.3 98 Gtg/Atg 0 +CDX2 UCSF GRCh37 13 28542701 28542701 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 11 82 0 ENST00000381020.7:c.443C>T p.Ala148Val p.A148V ENST00000381020 NM_001265.4 148 gCc/gTc 0 +CECR2 UCSF GRCh37 22 18021882 18021882 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 57 0 ENST00000262608.8:c.1987C>T p.Leu663= p.L663= ENST00000262608 NM_031413.3 663 Cta/Tta 0 +CELF6 UCSF GRCh37 15 72581778 72581778 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 21 112 0 ENST00000287202.5:c.818C>T p.Ala273Val p.A273V ENST00000287202 NM_052840.4 273 gCg/gTg 0 +CELSR2 UCSF GRCh37 1 109801126 109801126 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 13 107 0 ENST00000271332.3:c.3383G>A p.Ser1128Asn p.S1128N ENST00000271332 NM_001408.2 1128 aGc/aAc 0 +CELSR2 UCSF GRCh37 1 109806880 109806880 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 16 162 0 ENST00000271332.3:c.5182G>A p.Gly1728Ser p.G1728S ENST00000271332 NM_001408.2 1728 Ggc/Agc 0 +CELSR3 UCSF GRCh37 3 48698042 48698042 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 272 45 368 1 ENST00000164024.4:c.2026G>A p.Val676Ile p.V676I ENST00000164024 NM_001407.2 676 Gtc/Atc 0 +CELSR3 UCSF GRCh37 3 48681069 48681069 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 8 30 0 ENST00000164024.4:c.8207C>T p.Ala2736Val p.A2736V ENST00000164024 NM_001407.2 2736 gCc/gTc 0 +CENPB UCSF GRCh37 20 3766314 3766314 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 15 156 0 ENST00000379751.4:c.817G>A p.Ala273Thr p.A273T ENST00000379751 NM_001810.5 273 Gcc/Acc 0 +CENPO UCSF GRCh37 2 25016798 25016798 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 19 136 0 ENST00000380834.2:c.10G>A p.Ala4Thr p.A4T ENST00000380834 4 Gcg/Acg 0 +CEP112 UCSF GRCh37 17 64128857 64128857 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 15 136 0 ENST00000392769.2:c.495C>T p.Leu165= p.L165= ENST00000392769 NM_145036.3 165 ctC/ctT 0 +CEP135 UCSF GRCh37 4 56846433 56846433 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 25 96 0 ENST00000257287.4:c.1598G>A p.Arg533Lys p.R533K ENST00000257287 NM_025009.4 533 aGa/aAa 0 +CEP250 UCSF GRCh37 20 34092083 34092083 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 7 74 0 ENST00000397527.1:c.5886G>A p.Arg1962= p.R1962= ENST00000397527 NM_007186.3 1962 cgG/cgA 0 +CEP350 UCSF GRCh37 1 180059928 180059928 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 22 333 0 ENST00000367607.3:c.6505G>A p.Val2169Ile p.V2169I ENST00000367607 NM_014810.4 2169 Gtt/Att 0 +CEP85 UCSF GRCh37 1 26597537 26597537 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 23 159 1 ENST00000252992.4:c.1682G>A p.Ser561Asn p.S561N ENST00000252992 NM_022778.3 561 aGt/aAt 0 +CEP97 UCSF GRCh37 3 101450725 101450725 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 22 226 0 ENST00000341893.3:c.489G>A p.Met163Ile p.M163I ENST00000341893 163 atG/atA 0 +CFTR UCSF GRCh37 7 117232451 117232451 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 378 47 394 0 ENST00000003084.6:c.2230C>T p.Gln744Ter p.Q744* ENST00000003084 NM_000492.3 744 Cag/Tag 0 +CHD2 UCSF GRCh37 15 93540211 93540211 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 7 97 0 ENST00000394196.4:c.3620G>A p.Gly1207Asp p.G1207D ENST00000394196 NM_001271.3 1207 gGt/gAt 0 +CHD3 UCSF GRCh37 17 7806808 7806808 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 511 95 708 0 ENST00000380358.4:c.3891G>A p.Lys1297= p.K1297= ENST00000380358 NM_001005271.2 1297 aaG/aaA 0 +CHD8 UCSF GRCh37 14 21876526 21876526 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 12 147 0 ENST00000399982.2:c.2675G>A p.Ser892Asn p.S892N ENST00000399982 NM_001170629.1 892 aGt/aAt 0 +CHD9 UCSF GRCh37 16 53355489 53355489 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 10 134 0 ENST00000566029.1:c.7717G>A p.Glu2573Lys p.E2573K ENST00000566029 2573 Gaa/Aaa 0 +CHD9 UCSF GRCh37 16 53190970 53190970 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 44 387 0 ENST00000566029.1:c.969G>A p.Gln323= p.Q323= ENST00000566029 323 caG/caA 0 +CHFR UCSF GRCh37 12 133454233 133454233 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 8 118 0 ENST00000432561.2:c.141C>T p.Asp47= p.D47= ENST00000432561 47 gaC/gaT 0 +CHPF UCSF GRCh37 2 220404996 220404996 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 60 384 0 ENST00000243776.6:c.1437G>A p.Arg479= p.R479= ENST00000243776 NM_024536.5 479 cgG/cgA 0 +CHPF2 UCSF GRCh37 7 150934836 150934836 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 23 112 0 ENST00000035307.2:c.1388C>T p.Ala463Val p.A463V ENST00000035307 NM_019015.1 463 gCt/gTt 0 +CHRM4 UCSF GRCh37 11 46408064 46408064 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 224 32 293 0 ENST00000433765.2:c.44C>T p.Ser15Phe p.S15F ENST00000433765 NM_000741.2 15 tCc/tTc 0 +CHRNB2 UCSF GRCh37 1 154543944 154543944 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 298 39 370 0 ENST00000368476.3:c.645C>T p.Asn215= p.N215= ENST00000368476 NM_000748.2 215 aaC/aaT 0 +CHRNB2 UCSF GRCh37 1 154544313 154544313 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 31 310 0 ENST00000368476.3:c.1014C>T p.Val338= p.V338= ENST00000368476 NM_000748.2 338 gtC/gtT 0 +CHST12 UCSF GRCh37 7 2473490 2473490 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 39 415 0 ENST00000258711.6:c.1216C>T p.Pro406Ser p.P406S ENST00000258711 NM_001243794.1 406 Ccc/Tcc 0 +CHSY3 UCSF GRCh37 5 129240784 129240784 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 33 0 ENST00000305031.4:c.262C>T p.Leu88= p.L88= ENST00000305031 NM_175856.4 88 Ctg/Ttg 0 +CHUK UCSF GRCh37 10 101964296 101964296 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 48 386 0 ENST00000370397.7:c.1474G>A p.Glu492Lys p.E492K ENST00000370397 NM_001278.3 492 Gag/Aag 0 +CHURC1-FNTB UCSF GRCh37 14 65520017 65520017 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 16 141 0 ENST00000246166.2:c.1017C>T p.Ile339= p.I339= ENST00000246166 NM_002028.3 339 atC/atT 0 +CILP UCSF GRCh37 15 65490810 65490810 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 19 176 0 ENST00000261883.4:c.1814C>T p.Ser605Phe p.S605F ENST00000261883 NM_003613.3 605 tCc/tTc 0 +CITED2 UCSF GRCh37 6 139694288 139694288 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 495 89 625 0 ENST00000367651.2:c.794C>T p.Pro265Leu p.P265L ENST00000367651 NM_006079.4 265 cCc/cTc 0 +CKAP2L UCSF GRCh37 2 113514239 113514239 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 30 278 0 ENST00000302450.6:c.709C>T p.Leu237= p.L237= ENST00000302450 NM_152515.3 237 Ctg/Ttg 0 +CKM UCSF GRCh37 19 45810018 45810018 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 139 372 0 ENST00000221476.3:c.1136C>T p.Ala379Val p.A379V ENST00000221476 NM_001824.4 379 gCc/gTc 0 +CLCA2 UCSF GRCh37 1 86920950 86920950 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 332 63 560 0 ENST00000370565.4:c.2572G>A p.Glu858Lys p.E858K ENST00000370565 NM_006536.5 858 Gaa/Aaa 0 +CLCNKA UCSF GRCh37 1 16356567 16356567 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 8 72 0 ENST00000331433.4:c.1405G>A p.Ala469Thr p.A469T ENST00000331433 469 Gca/Aca 0 +CLDN25 UCSF GRCh37 11 113651151 113651151 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 63 433 0 ENST00000453129.2:c.634G>A p.Glu212Lys p.E212K ENST00000453129 NM_001101389.1 212 Gag/Aag 0 +CLEC10A UCSF GRCh37 17 6978505 6978505 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 24 158 0 ENST00000254868.4:c.819G>A p.Gly273= p.G273= ENST00000254868 NM_182906.2 273 ggG/ggA 0 +CLIP1 UCSF GRCh37 12 122825374 122825374 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 247 43 341 0 ENST00000540338.1:c.2377C>T p.Leu793Phe p.L793F ENST00000540338 793 Ctt/Ttt 0 +CLIP2 UCSF GRCh37 7 73787293 73787293 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 31 105 0 ENST00000223398.6:c.1412G>A p.Gly471Glu p.G471E ENST00000223398 NM_003388.4 471 gGg/gAg 0 +CLIP3 UCSF GRCh37 19 36508860 36508860 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 12 108 0 ENST00000360535.4:c.1217G>A p.Gly406Asp p.G406D ENST00000360535 NM_015526.2 406 gGc/gAc 0 +CLIP4 UCSF GRCh37 2 29366752 29366752 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 33 211 0 ENST00000320081.5:c.826G>A p.Ala276Thr p.A276T ENST00000320081 NM_024692.4 276 Gca/Aca 0 +CLK1 UCSF GRCh37 2 201719370 201719370 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 12 131 0 ENST00000434813.2:c.1315C>T p.Pro439Ser p.P439S ENST00000434813 NM_001162407.1 439 Cct/Tct 0 +CLNK UCSF GRCh37 4 10542122 10542122 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 356 66 489 1 ENST00000226951.6:c.598C>T p.Pro200Ser p.P200S ENST00000226951 NM_052964.2 200 Ccc/Tcc 0 +CLP1 UCSF GRCh37 11 57427059 57427059 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 101 311 0 ENST00000533682.1:c.111G>A p.Leu37= p.L37= ENST00000533682 37 ttG/ttA 0 +CLRN2 UCSF GRCh37 4 17528641 17528641 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 228 28 316 0 ENST00000511148.2:c.635C>T p.Pro212Leu p.P212L ENST00000511148 NM_001079827.2 212 cCc/cTc 0 +CLSPN UCSF GRCh37 1 36215397 36215397 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 34 0 ENST00000318121.3:c.2044C>T p.Leu682Phe p.L682F ENST00000318121 NM_022111.3 682 Ctt/Ttt 0 +CLSPN UCSF GRCh37 1 36213585 36213585 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 32 209 0 ENST00000318121.3:c.2550G>A p.Lys850= p.K850= ENST00000318121 NM_022111.3 850 aaG/aaA 0 +CLSTN2 UCSF GRCh37 3 140178480 140178480 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 28 222 1 ENST00000458420.3:c.1091C>T p.Ala364Val p.A364V ENST00000458420 NM_022131.2 364 gCc/gTc 0 +CLSTN2 UCSF GRCh37 3 140282922 140282922 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 19 166 0 ENST00000458420.3:c.2602G>A p.Ala868Thr p.A868T ENST00000458420 NM_022131.2 868 Gct/Act 0 +CLTCL1 UCSF GRCh37 22 19230420 19230420 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 21 232 0 ENST00000263200.10:c.559G>A p.Asp187Asn p.D187N ENST00000263200 NM_007098.3 187 Gat/Aat 0 +CLUAP1 UCSF GRCh37 16 3582786 3582786 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 30 225 0 ENST00000576634.1:c.1037G>A p.Gly346Glu p.G346E ENST00000576634 NM_015041.2 346 gGa/gAa 0 +CLVS2 UCSF GRCh37 6 123319024 123319024 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 31 202 0 ENST00000275162.5:c.102G>A p.Val34= p.V34= ENST00000275162 NM_001010852.3 34 gtG/gtA 0 +CMYA5 UCSF GRCh37 5 79030057 79030057 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 33 355 0 ENST00000446378.2:c.5469G>A p.Lys1823= p.K1823= ENST00000446378 NM_153610.3 1823 aaG/aaA 0 +CNR1 UCSF GRCh37 6 88854268 88854268 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 33 236 0 ENST00000537554.1:c.726C>T p.Thr242= p.T242= ENST00000537554 NM_001160258.1 242 acC/acT 0 +CNTN5 UCSF GRCh37 11 99715592 99715592 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 27 206 0 ENST00000524871.1:c.286G>A p.Asp96Asn p.D96N ENST00000524871 NM_014361.3 96 Gac/Aac 0 +CNTN5 UCSF GRCh37 11 99941273 99941273 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 3 18 0 ENST00000524871.1:c.1280G>A p.Gly427Glu p.G427E ENST00000524871 NM_014361.3 427 gGa/gAa 0 +CNTN6 UCSF GRCh37 3 1367580 1367580 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 208 31 312 0 ENST00000446702.2:c.1028G>A p.Gly343Glu p.G343E ENST00000446702 343 gGa/gAa 0 +COBL UCSF GRCh37 7 51096010 51096010 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 381 75 577 0 ENST00000265136.7:c.2783G>A p.Gly928Asp p.G928D ENST00000265136 NM_015198.3 928 gGt/gAt 0 +COBL UCSF GRCh37 7 51152960 51152960 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 14 57 0 ENST00000265136.7:c.999G>A p.Arg333= p.R333= ENST00000265136 NM_015198.3 333 cgG/cgA 0 +COG2 UCSF GRCh37 1 230829119 230829119 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 31 167 0 ENST00000366669.4:c.2197G>A p.Ala733Thr p.A733T ENST00000366669 NM_001145036.1 733 Gca/Aca 0 +COG2 UCSF GRCh37 1 230827142 230827142 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 13 164 0 ENST00000366669.4:c.1947C>T p.Thr649= p.T649= ENST00000366669 NM_001145036.1 649 acC/acT 0 +COL11A1 UCSF GRCh37 1 103352413 103352413 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 20 210 0 ENST00000370096.3:c.4808C>A p.Pro1603Gln p.P1603Q ENST00000370096 NM_001854.3 1603 cCa/cAa 0 +COL11A2 UCSF GRCh37 6 33143431 33143431 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 19 107 0 ENST00000374708.4:c.2038G>A p.Gly680Arg p.G680R ENST00000374708 NM_080681.2 680 Gga/Aga 0 +COL12A1 UCSF GRCh37 6 75848226 75848226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 24 228 0 ENST00000322507.8:c.5168C>T p.Ser1723Phe p.S1723F ENST00000322507 NM_004370.5 1723 tCc/tTc 0 +COL12A1 UCSF GRCh37 6 75893059 75893059 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 24 192 0 ENST00000322507.8:c.1598C>T p.Pro533Leu p.P533L ENST00000322507 NM_004370.5 533 cCt/cTt 0 +COL18A1 UCSF GRCh37 21 46925147 46925147 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 13 125 0 ENST00000355480.5:c.3508C>T p.Pro1170Ser p.P1170S ENST00000355480 NM_030582.3 1170 Cca/Tca 0 +COL20A1 UCSF GRCh37 20 61943349 61943349 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 9 65 0 ENST00000358894.6:c.1745G>A p.Arg582Lys p.R582K ENST00000358894 NM_020882.2 582 aGg/aAg 0 +COL20A1 UCSF GRCh37 20 61945187 61945187 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 9 99 0 ENST00000358894.6:c.2302G>A p.Val768Met p.V768M ENST00000358894 NM_020882.2 768 Gtg/Atg 0 +COL23A1 UCSF GRCh37 5 177684567 177684567 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 107 0 ENST00000390654.3:c.731G>A p.Gly244Asp p.G244D ENST00000390654 NM_173465.3 244 gGc/gAc 0 +COL24A1 UCSF GRCh37 1 86591741 86591741 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 22 287 0 ENST00000370571.2:c.278C>T p.Pro93Leu p.P93L ENST00000370571 NM_152890.5 93 cCt/cTt 0 +COL27A1 UCSF GRCh37 9 117068906 117068906 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 29 191 0 ENST00000356083.3:c.5045C>T p.Thr1682Ile p.T1682I ENST00000356083 NM_032888.2 1682 aCc/aTc 0 +COL28A1 UCSF GRCh37 7 7483230 7483230 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 182 21 192 0 ENST00000399429.3:c.1636C>T p.Gln546Ter p.Q546* ENST00000399429 NM_001037763.2 546 Cag/Tag 0 +COL2A1 UCSF GRCh37 12 48375911 48375911 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.00399,snp132_rs35504014 P24_Rec2 Untested WXS Illumina HiSeq 108 15 134 0 ENST00000380518.3:c.2334C>T p.Ala778= p.A778= ENST00000380518 NM_033150.2 778 gcC/gcT 0 +COL2A1 UCSF GRCh37 12 48380671 48380671 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 24 193 0 ENST00000380518.3:c.1366G>A p.Gly456Ser p.G456S ENST00000380518 NM_033150.2 456 Ggt/Agt 0 +COL3A1 UCSF GRCh37 2 189868993 189868993 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 24 98 0 ENST00000304636.3:c.2834G>A p.Gly945Asp p.G945D ENST00000304636 NM_000090.3 945 gGc/gAc 0 +COL3A1 UCSF GRCh37 2 189868138 189868138 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 11 53 0 ENST00000304636.3:c.2555G>A p.Gly852Asp p.G852D ENST00000304636 NM_000090.3 852 gGt/gAt 0 +COL4A3BP UCSF GRCh37 5 74676916 74676916 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 22 245 0 ENST00000380494.5:c.2112G>A p.Lys704= p.K704= ENST00000380494 NM_001130105.1 704 aaG/aaA 0 +COL5A3 UCSF GRCh37 19 10089569 10089569 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 5 30 0 ENST00000264828.3:c.2962C>T p.Pro988Ser p.P988S ENST00000264828 NM_015719.3 988 Ccg/Tcg 0 +COL5A3 UCSF GRCh37 19 10089303 10089303 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 12 68 0 ENST00000264828.3:c.2965G>A p.Gly989Arg p.G989R ENST00000264828 NM_015719.3 989 Gga/Aga 0 +COL6A2 UCSF GRCh37 21 47546141 47546141 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 13 87 0 ENST00000300527.4:c.2412C>T p.Val804= p.V804= ENST00000300527 NM_001849.3 804 gtC/gtT 0 +COL6A3 UCSF GRCh37 2 238280963 238280963 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 17 156 0 ENST00000295550.4:c.3697G>A p.Asp1233Asn p.D1233N ENST00000295550 NM_004369.3 1233 Gac/Aac 0 +COL6A3 UCSF GRCh37 2 238242168 238242168 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 12 97 0 ENST00000295550.4:c.9253C>T p.Gln3085Ter p.Q3085* ENST00000295550 NM_004369.3 3085 Cag/Tag 0 +COL7A1 UCSF GRCh37 3 48612894 48612894 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 12 148 0 ENST00000328333.8:c.6058G>A p.Ala2020Thr p.A2020T ENST00000328333 NM_000094.3 2020 Gcc/Acc 0 +COL7A1 UCSF GRCh37 3 48618560 48618560 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 215 102 281 0 ENST00000328333.8:c.4930C>T p.Pro1644Ser p.P1644S ENST00000328333 NM_000094.3 1644 Cct/Tct 0 +COL7A1 UCSF GRCh37 3 48627934 48627934 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 306 56 477 1 ENST00000328333.8:c.1864C>T p.Pro622Ser p.P622S ENST00000328333 NM_000094.3 622 Cct/Tct 0 +COL7A1 UCSF GRCh37 3 48612931 48612931 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 17 134 0 ENST00000328333.8:c.6021C>T p.Asp2007= p.D2007= ENST00000328333 NM_000094.3 2007 gaC/gaT 0 +COL9A2 UCSF GRCh37 1 40776907 40776907 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 18 157 0 ENST00000372748.3:c.571G>A p.Val191Met p.V191M ENST00000372748 NM_001852.3 191 Gtg/Atg 0 +COLEC11 UCSF GRCh37 2 3691697 3691697 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 20 212 0 ENST00000418971.2:c.847G>A p.Glu283Lys p.E283K ENST00000418971 NM_001255985.1 283 Gag/Aag 0 +COMP UCSF GRCh37 19 18895739 18895739 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 9 65 0 ENST00000222271.2:c.1881C>T p.Phe627= p.F627= ENST00000222271 NM_000095.2 627 ttC/ttT 0 +COPS5 UCSF GRCh37 8 67971558 67971558 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 446 77 707 0 ENST00000357849.4:c.266C>T p.Thr89Ile p.T89I ENST00000357849 NM_006837.2 89 aCc/aTc 0 +COPS6 UCSF GRCh37 7 99687306 99687306 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 21 203 0 ENST00000303904.3:c.271T>C p.Ser91Pro p.S91P ENST00000303904 NM_006833.4 91 Tcc/Ccc 0 +COX11 UCSF GRCh37 17 53040774 53040774 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 193 39 348 0 ENST00000299335.3:c.541G>A p.Ala181Thr p.A181T ENST00000299335 NM_004375.3 181 Gca/Aca 0 +CPA4 UCSF GRCh37 7 129950789 129950789 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 6 39 0 ENST00000222482.4:c.956G>A p.Gly319Glu p.G319E ENST00000222482 NM_016352.3 319 gGg/gAg 0 +CPAMD8 UCSF GRCh37 19 17088233 17088233 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 15 50 0 ENST00000443236.1:c.1844G>A p.Gly615Glu p.G615E ENST00000443236 NM_015692.2 615 gGa/gAa 0 +CPN1 UCSF GRCh37 10 101825120 101825120 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 4 95 0 ENST00000370418.3:c.584C>T p.Pro195Leu p.P195L ENST00000370418 NM_001308.2 195 cCc/cTc 0 +CPNE2 UCSF GRCh37 16 57144746 57144746 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 5 115 0 ENST00000535318.2:c.92G>A p.Ser31Asn p.S31N ENST00000535318 31 aGt/aAt 0 +CPNE2 UCSF GRCh37 16 57149387 57149387 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 10 168 0 ENST00000535318.2:c.361-1G>A p.X121_splice ENST00000535318 0 +CPNE3 UCSF GRCh37 8 87540889 87540889 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 6 57 0 ENST00000521271.1:c.116G>A p.Gly39Asp p.G39D ENST00000521271 NM_003909.3 39 gGt/gAt 0 +CPNE6 UCSF GRCh37 14 24542228 24542228 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 9 55 1 ENST00000397016.2:c.83G>A p.Cys28Tyr p.C28Y ENST00000397016 NM_001280558.1 28 tGc/tAc 0 +CPNE7 UCSF GRCh37 16 89642466 89642466 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 10 56 0 ENST00000268720.5:c.161G>A p.Gly54Asp p.G54D ENST00000268720 NM_014427.4 54 gGc/gAc 0 +CPS1 UCSF GRCh37 2 211512707 211512707 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 6 63 0 ENST00000430249.2:c.3280G>A p.Asp1094Asn p.D1094N ENST00000430249 NM_001122633.2 1094 Gat/Aat 0 +CPSF1 UCSF GRCh37 8 145626860 145626860 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 30 271 0 ENST00000349769.3:c.270G>A p.Lys90= p.K90= ENST00000349769 NM_013291.2 90 aaG/aaA 0 +CPT1C UCSF GRCh37 19 50195544 50195544 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 29 94 0 ENST00000392518.4:c.35C>G p.Pro12Arg p.P12R ENST00000392518 NM_001199752.1 12 cCc/cGc 0 +CPXCR1 UCSF GRCh37 X 88009037 88009037 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 26 181 0 ENST00000276127.4:c.622C>T p.Leu208Phe p.L208F ENST00000276127 NM_033048.5 208 Ctc/Ttc 0 +CR2 UCSF GRCh37 1 207648192 207648192 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 4 58 0 ENST00000367057.3:c.2347G>A p.Val783Met p.V783M ENST00000367057 NM_001006658.2 783 Gtg/Atg 0 +CRAT UCSF GRCh37 9 131858276 131858276 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 16 142 0 ENST00000318080.2:c.1665+1G>A p.X555_splice ENST00000318080 NM_001257363.1 0 +CRB2 UCSF GRCh37 9 126135458 126135458 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 4 37 0 ENST00000373631.3:c.2648G>A p.Ser883Asn p.S883N ENST00000373631 NM_173689.5 883 aGc/aAc 0 +CREBBP UCSF GRCh37 16 3779736 3779736 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 23 219 0 ENST00000262367.5:c.5312G>A p.Ser1771Asn p.S1771N ENST00000262367 NM_004380.2 1771 aGc/aAc 0 +CRIM1 UCSF GRCh37 2 36775817 36775817 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 381 54 533 0 ENST00000280527.2:c.3084G>A p.Gln1028= p.Q1028= ENST00000280527 NM_016441.2 1028 caG/caA 0 +CRIPT UCSF GRCh37 2 46851351 46851351 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 23 279 0 ENST00000238892.3:c.291G>A p.Lys97= p.K97= ENST00000238892 NM_014171.4 97 aaG/aaA 0 +CRTC1 UCSF GRCh37 19 18870884 18870884 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 10 77 0 ENST00000338797.6:c.780G>A p.Gly260= p.G260= ENST00000338797 NM_001098482.1 260 ggG/ggA 0 +CRTC2 UCSF GRCh37 1 153921856 153921856 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 17 61 0 ENST00000368633.1:c.1409T>C p.Val470Ala p.V470A ENST00000368633 NM_181715.2 470 gTc/gCc 0 +CRTC3 UCSF GRCh37 15 91150639 91150639 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 38 287 0 ENST00000268184.6:c.506G>A p.Ser169Asn p.S169N ENST00000268184 169 aGt/aAt 0 +CRYZ UCSF GRCh37 1 75190394 75190394 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 9 91 0 ENST00000417775.1:c.111+1G>A p.X37_splice ENST00000417775 NM_001130042.1 0 +CSF1 UCSF GRCh37 1 110466112 110466112 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 196 31 272 0 ENST00000329608.6:c.869G>A p.Gly290Glu p.G290E ENST00000329608 NM_000757.5 290 gGg/gAg 0 +CSF2RB UCSF GRCh37 22 37325470 37325470 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 15 37 0 ENST00000403662.3:c.418C>T p.Gln140Ter p.Q140* ENST00000403662 140 Cag/Tag 0 +CSMD1 UCSF GRCh37 8 2836219 2836219 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 222 29 176 0 ENST00000537824.1:c.8481C>T p.Cys2827= p.C2827= ENST00000537824 NM_033225.5 2827 tgC/tgT 0 +CSPP1 UCSF GRCh37 8 68049803 68049803 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 12 121 0 ENST00000262210.5:c.1925G>A p.Gly642Asp p.G642D ENST00000262210 NM_024790.6 642 gGt/gAt 0 +CSRNP2 UCSF GRCh37 12 51457544 51457544 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 16 95 0 ENST00000228515.1:c.1617C>T p.Leu539= p.L539= ENST00000228515 NM_030809.2 539 ctC/ctT 0 +CTNNA2 UCSF GRCh37 2 79878746 79878746 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 12 165 0 ENST00000466387.1:c.64C>T p.Leu22= p.L22= ENST00000466387 22 Cta/Tta 0 +CTR9 UCSF GRCh37 11 10777265 10777265 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 12 64 0 ENST00000361367.2:c.425G>A p.Gly142Asp p.G142D ENST00000361367 NM_014633.3 142 gGt/gAt 0 +CTSL1 UCSF GRCh37 9 90343719 90343719 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 335 194 674 0 ENST00000343150.5:c.616G>A p.Ala206Thr p.A206T ENST00000343150 206 Gca/Aca 0 +CTSO UCSF GRCh37 4 156864339 156864339 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 8 192 0 ENST00000433477.3:c.213G>A p.Gln71= p.Q71= ENST00000433477 NM_001334.2 71 caG/caA 0 +CTTNBP2 UCSF GRCh37 7 117451031 117451031 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 12 101 0 ENST00000160373.3:c.202G>A p.Glu68Lys p.E68K ENST00000160373 NM_033427.2 68 Gag/Aag 0 +CTTNBP2NL UCSF GRCh37 1 112991673 112991673 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 26 134 0 ENST00000271277.6:c.209G>A p.Gly70Asp p.G70D ENST00000271277 NM_018704.2 70 gGc/gAc 0 +CUL4B UCSF GRCh37 X 119680994 119680994 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 4 35 0 ENST00000404115.3:c.827G>A p.Arg276Lys p.R276K ENST00000404115 NM_003588.3 276 aGa/aAa 0 +CUL9 UCSF GRCh37 6 43184060 43184060 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 22 250 0 ENST00000252050.4:c.6101G>A p.Gly2034Asp p.G2034D ENST00000252050 NM_015089.2 2034 gGc/gAc 0 +CUX1 UCSF GRCh37 7 101460925 101460925 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 7 55 0 ENST00000360264.3:c.63+1552G>A *21* ENST00000360264 NM_001202543.1 0 +CWC27 UCSF GRCh37 5 64077783 64077783 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 17 110 0 ENST00000381070.3:c.175C>T p.Pro59Ser p.P59S ENST00000381070 NM_005869.2 59 Cct/Tct 0 +CXCL11 UCSF GRCh37 4 76956392 76956392 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 26 207 0 ENST00000306621.3:c.165C>T p.Asn55= p.N55= ENST00000306621 NM_005409.4 55 aaC/aaT 0 +CXCL2 UCSF GRCh37 4 74964383 74964383 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 18 180 0 ENST00000508487.2:c.243G>A p.Gly81= p.G81= ENST00000508487 NM_002089.3 81 ggG/ggA 0 +CXCL3 UCSF GRCh37 4 74902982 74902982 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 24 174 0 ENST00000296026.4:c.321C>T p.Asn107= p.N107= ENST00000296026 NM_002090.2 107 aaC/aaT 0 +CXorf26 UCSF GRCh37 X 75394773 75394773 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 31 120 0 ENST00000373358.3:c.145G>A p.Val49Ile p.V49I ENST00000373358 NM_016500.3 49 Gtc/Atc 0 +CXorf59 UCSF GRCh37 X 36103639 36103639 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 21 114 0 ENST00000313548.4:c.625C>T p.Leu209Phe p.L209F ENST00000313548 NM_173695.2 209 Ctt/Ttt 0 +CXXC1 UCSF GRCh37 18 47811482 47811482 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 279 57 395 0 ENST00000412036.2:c.802G>A p.Glu268Lys p.E268K ENST00000412036 268 Gag/Aag 0 +CYB561 UCSF GRCh37 17 61514898 61514898 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 4 51 0 ENST00000392976.1:c.11G>A p.Gly4Glu p.G4E ENST00000392976 NM_001017916.1 4 gGg/gAg 0 +CYB5D1 UCSF GRCh37 17 7761524 7761524 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 5 40 0 ENST00000332439.4:c.72G>A p.Glu24= p.E24= ENST00000332439 NM_144607.4 24 gaG/gaA 0 +CYB5R1 UCSF GRCh37 1 202931713 202931713 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 18 119 0 ENST00000367249.4:c.860C>T p.Ala287Val p.A287V ENST00000367249 NM_016243.2 287 gCc/gTc 0 +CYB5R4 UCSF GRCh37 6 84574011 84574011 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 84 0 ENST00000369681.5:c.193C>T p.His65Tyr p.H65Y ENST00000369681 NM_016230.3 65 Cac/Tac 0 +CYFIP1 UCSF GRCh37 15 22993035 22993035 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 33 0 ENST00000313077.7:c.2922G>A p.Glu974= p.E974= ENST00000313077 NM_014608.2 974 gaG/gaA 0 +CYLD UCSF GRCh37 16 50810181 50810181 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 4 61 0 ENST00000398568.2:c.1005G>A p.Lys335= p.K335= ENST00000398568 NM_001042412.1 335 aaG/aaA 0 +CYP24A1 UCSF GRCh37 20 52789884 52789884 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 310 37 403 0 ENST00000216862.3:c.235C>T p.Leu79Phe p.L79F ENST00000216862 NM_000782.4 79 Ctc/Ttc 0 +CYP3A7 UCSF GRCh37 7 99306796 99306796 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 47 338 0 ENST00000336374.2:c.1115G>A p.Arg372Lys p.R372K ENST00000336374 NM_000765.3 372 aGa/aAa 0 +CYP46A1 UCSF GRCh37 14 100187631 100187631 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 11 109 0 ENST00000261835.3:c.1036G>A p.Asp346Asn p.D346N ENST00000261835 NM_006668.1 346 Gac/Aac 0 +CYP4F11 UCSF GRCh37 19 16045165 16045165 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 13 52 0 ENST00000402119.4:c.54G>A p.Pro18= p.P18= ENST00000402119 NM_021187.3 18 ccG/ccA 0 +CYP4F2 UCSF GRCh37 19 15989703 15989703 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 5 17 0 ENST00000221700.6:c.1441G>A p.Val481Ile p.V481I ENST00000221700 NM_001082.3 481 Gtc/Atc 0 +CYTH1 UCSF GRCh37 17 76697834 76697834 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 30 95 0 ENST00000361101.4:c.357-1G>A p.X119_splice ENST00000361101 NM_017456.2 0 +CYTIP UCSF GRCh37 2 158290915 158290915 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 95 427 0 ENST00000264192.3:c.246G>A p.Lys82= p.K82= ENST00000264192 NM_004288.4 82 aaG/aaA 0 +DAAM2 UCSF GRCh37 6 39846317 39846317 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 11 103 0 ENST00000398904.2:c.1498G>A p.Ala500Thr p.A500T ENST00000398904 500 Gct/Act 0 +DACT2 UCSF GRCh37 6 168709332 168709332 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 332 38 437 1 ENST00000366795.3:c.1105G>A p.Gly369Ser p.G369S ENST00000366795 NM_214462.3 369 Ggt/Agt 0 +DAGLA UCSF GRCh37 11 61502445 61502445 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 33 214 0 ENST00000257215.5:c.1099G>A p.Asp367Asn p.D367N ENST00000257215 NM_006133.2 367 Gac/Aac 0 +DAGLA UCSF GRCh37 11 61511131 61511131 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 4 59 0 ENST00000257215.5:c.2299G>A p.Ala767Thr p.A767T ENST00000257215 NM_006133.2 767 Gcg/Acg 0 +DAK UCSF GRCh37 11 61113195 61113195 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 32 299 0 ENST00000394900.3:c.1463C>T p.Ala488Val p.A488V ENST00000394900 NM_015533.3 488 gCt/gTt 0 +DAK UCSF GRCh37 11 61108958 61108958 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 24 196 0 ENST00000394900.3:c.537G>A p.Lys179= p.K179= ENST00000394900 NM_015533.3 179 aaG/aaA 0 +DAOA UCSF GRCh37 13 106125018 106125018 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 3 47 0 ENST00000375936.3:c.265C>T p.Pro89Ser p.P89S ENST00000375936 NM_001161812.1 89 Cct/Tct 0 +DAP3 UCSF GRCh37 1 155695795 155695795 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 13 150 0 ENST00000368336.5:c.457C>T p.Leu153= p.L153= ENST00000368336 NM_004632.3 153 Cta/Tta 0 +DARS2 UCSF GRCh37 1 173825858 173825858 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 21 216 0 ENST00000361951.4:c.1729C>T p.Pro577Ser p.P577S ENST00000361951 NM_018122.4 577 Cct/Tct 0 +DAXX UCSF GRCh37 6 33286520 33286520 + stop_retained_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 16 82 0 ENST00000374542.5:c.2223G>A p.Ter741= p.*741= ENST00000374542 NM_001141970.1 741 taG/taA 0 +DBC1 UCSF GRCh37 9 121929590 121929590 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 31 279 0 ENST00000265922.3:c.2058C>T p.Phe686= p.F686= ENST00000265922 NM_014618.2 686 ttC/ttT 0 +DBR1 UCSF GRCh37 3 137881420 137881420 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 9 82 0 ENST00000260803.4:c.946G>A p.Asp316Asn p.D316N ENST00000260803 NM_016216.3 316 Gat/Aat 0 +DBR1 UCSF GRCh37 3 137885932 137885932 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 8 70 0 ENST00000260803.4:c.705G>A p.Met235Ile p.M235I ENST00000260803 NM_016216.3 235 atG/atA 0 +DCAF6 UCSF GRCh37 1 167921037 167921037 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 13 149 0 ENST00000367840.3:c.98-1G>A p.X33_splice ENST00000367840 NM_001198956.1 0 +DCHS1 UCSF GRCh37 11 6645226 6645226 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 30 302 0 ENST00000299441.3:c.7681G>A p.Asp2561Asn p.D2561N ENST00000299441 NM_003737.2 2561 Gac/Aac 0 +DCLK2 UCSF GRCh37 4 151145687 151145687 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 16 148 0 ENST00000302176.8:c.1327G>A p.Asp443Asn p.D443N ENST00000302176 NM_001040261.4 443 Gac/Aac 0 +DCLK3 UCSF GRCh37 3 36779519 36779519 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 127 467 0 ENST00000416516.2:c.632C>T p.Thr211Ile p.T211I ENST00000416516 NM_033403.1 211 aCt/aTt 0 +DCLRE1A UCSF GRCh37 10 115603981 115603981 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 12 113 0 ENST00000361384.2:c.2401C>T p.Leu801Phe p.L801F ENST00000361384 NM_014881.4 801 Ctc/Ttc 0 +DCST1 UCSF GRCh37 1 155019721 155019721 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 30 235 0 ENST00000295542.1:c.1545G>A p.Arg515= p.R515= ENST00000295542 NM_152494.3 515 cgG/cgA 0 +DCST2 UCSF GRCh37 1 155002654 155002654 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 12 117 0 ENST00000368424.3:c.1083C>T p.Ser361= p.S361= ENST00000368424 NM_144622.2 361 agC/agT 0 +DCT UCSF GRCh37 13 95114294 95114294 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 26 194 0 ENST00000446125.1:c.1013C>T p.Pro338Leu p.P338L ENST00000446125 NM_001129889.1 338 cCc/cTc 0 +DCTN2 UCSF GRCh37 12 57927880 57927880 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 685 80 117 0 ENST00000434715.3:c.540G>A p.Lys180= p.K180= ENST00000434715 NM_006400.4 180 aaG/aaA 0 +DDIT4 UCSF GRCh37 10 74034840 74034840 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 138 42 330 0 ENST00000307365.3:c.593C>T p.Ser198Phe p.S198F ENST00000307365 NM_019058.2 198 tCt/tTt 0 +DDOST UCSF GRCh37 1 20982629 20982629 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 12 50 0 ENST00000375048.3:c.368G>A p.Gly123Glu p.G123E ENST00000375048 NM_005216.4 123 gGa/gAa 0 +DDX18 UCSF GRCh37 2 118575155 118575155 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 10 49 0 ENST00000263239.2:c.221C>T p.Ser74Phe p.S74F ENST00000263239 NM_006773.3 74 tCt/tTt 0 +DDX39B UCSF GRCh37 6 31498696 31498696 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 20 135 0 ENST00000396172.1:c.1130G>A p.Arg377Lys p.R377K ENST00000396172 NM_004640.6 377 aGa/aAa 0 +DDX39B UCSF GRCh37 6 31504281 31504281 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 460 58 687 0 ENST00000396172.1:c.612G>A p.Gln204= p.Q204= ENST00000396172 NM_004640.6 204 caG/caA 0 +DDX54 UCSF GRCh37 12 113602091 113602091 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 15 124 0 ENST00000314045.7:c.1720-1G>A p.X574_splice ENST00000314045 NM_001111322.1 0 +DDX60L UCSF GRCh37 4 169294816 169294816 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 62 491 0 ENST00000260184.7:c.4776+1G>A p.X1592_splice ENST00000260184 NM_001012967.1 0 +DECR2 UCSF GRCh37 16 461398 461398 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 24 146 0 ENST00000219481.5:c.699C>T p.Ala233= p.A233= ENST00000219481 NM_020664.3 233 gcC/gcT 0 +DEFA5 UCSF GRCh37 8 6914189 6914189 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 32 0 ENST00000330590.2:c.31C>T p.Leu11Phe p.L11F ENST00000330590 NM_021010.1 11 Ctc/Ttc 0 +DEGS1 UCSF GRCh37 1 224377858 224377858 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 258 53 384 0 ENST00000323699.4:c.662G>A p.Gly221Asp p.G221D ENST00000323699 NM_003676.3 221 gGt/gAt 0 +DENND1A UCSF GRCh37 9 126144555 126144555 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 19 151 0 ENST00000373624.2:c.2186C>T p.Ala729Val p.A729V ENST00000373624 NM_020946.1 729 gCc/gTc 0 +DENND2A UCSF GRCh37 7 140301242 140301242 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 13 103 0 ENST00000275884.6:c.956G>A p.Arg319Lys p.R319K ENST00000275884 319 aGa/aAa 0 +DENND4A UCSF GRCh37 15 65994642 65994642 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 61 0 ENST00000443035.3:c.2430+1G>A p.X810_splice ENST00000443035 NM_001144823.1 0 +DENND5B UCSF GRCh37 12 31555512 31555512 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 18 168 0 ENST00000389082.5:c.2869C>T p.Pro957Ser p.P957S ENST00000389082 NM_144973.3 957 Cct/Tct 0 +DENND5B UCSF GRCh37 12 31552652 31552652 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 14 126 0 ENST00000389082.5:c.3004C>T p.Leu1002= p.L1002= ENST00000389082 NM_144973.3 1002 Ctg/Ttg 0 +DEPDC7 UCSF GRCh37 11 33054986 33054986 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 243 47 377 0 ENST00000241051.3:c.1521G>A p.Glu507= p.E507= ENST00000241051 NM_001077242.1 507 gaG/gaA 0 +DES UCSF GRCh37 2 220286117 220286117 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 47 154 0 ENST00000373960.3:c.1079C>T p.Ala360Val p.A360V ENST00000373960 NM_001927.3 360 gCc/gTc 0 +DFFB UCSF GRCh37 1 3775390 3775390 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 25 139 0 ENST00000378209.3:c.223G>A p.Gly75Ser p.G75S ENST00000378209 NM_004402.2 75 Ggc/Agc 0 +DHRS4L1 UCSF GRCh37 14 24505775 24505775 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 62 195 0 ENST00000606840.1:n.66C>T *22* ENST00000606840 0 +DHTKD1 UCSF GRCh37 10 12160815 12160815 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 211 40 159 0 ENST00000263035.4:c.2470G>A p.Gly824Arg p.G824R ENST00000263035 NM_018706.6 824 Ggg/Agg 0 +DHX15 UCSF GRCh37 4 24529649 24529649 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 18 165 0 ENST00000336812.4:c.2286C>T p.Ala762= p.A762= ENST00000336812 NM_001358.2 762 gcC/gcT 0 +DHX33 UCSF GRCh37 17 5358557 5358557 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 17 194 0 ENST00000225296.3:c.1070C>T p.Ala357Val p.A357V ENST00000225296 NM_001199699.1 357 gCt/gTt 0 +DHX58 UCSF GRCh37 17 40253810 40253810 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 10 100 0 ENST00000251642.3:c.2006C>T p.Ala669Val p.A669V ENST00000251642 NM_024119.2 669 gCc/gTc 0 +DIDO1 UCSF GRCh37 20 61542417 61542417 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 219 36 321 0 ENST00000266070.4:c.548G>A p.Gly183Glu p.G183E ENST00000266070 NM_033081.2 183 gGg/gAg 0 +DIEXF UCSF GRCh37 1 210010214 210010214 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 219 112 464 0 ENST00000491415.2:c.720G>A p.Lys240= p.K240= ENST00000491415 NM_014388.6 240 aaG/aaA 0 +DIP2B UCSF GRCh37 12 51097957 51097957 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 16 96 0 ENST00000301180.5:c.2360G>A p.Gly787Glu p.G787E ENST00000301180 NM_173602.2 787 gGg/gAg 0 +DIP2C UCSF GRCh37 10 329328 329328 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 8 59 0 ENST00000280886.6:c.4178C>T p.Ser1393Phe p.S1393F ENST00000280886 NM_014974.2 1393 tCc/tTc 0 +DIRAS1 UCSF GRCh37 19 2717666 2717666 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 196 22 154 0 ENST00000323469.4:c.139G>A p.Val47Met p.V47M ENST00000323469 NM_145173.3 47 Gtg/Atg 0 +DIS3L UCSF GRCh37 15 66587480 66587480 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 13 130 0 ENST00000319212.4:c.293+1G>A p.X98_splice ENST00000319212 NM_001143688.1 0 +DLAT UCSF GRCh37 11 111896382 111896382 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 17 110 0 ENST00000280346.6:c.186C>T p.Thr62= p.T62= ENST00000280346 NM_001931.4 62 acC/acT 0 +DLC1 UCSF GRCh37 8 12957533 12957533 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 299 36 333 0 ENST00000276297.4:c.2313G>A p.Arg771= p.R771= ENST00000276297 NM_182643.2 771 cgG/cgA 0 +DMAP1 UCSF GRCh37 1 44684349 44684349 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 240 41 358 0 ENST00000372289.2:c.642G>A p.Lys214= p.K214= ENST00000372289 NM_019100.4 214 aaG/aaA 0 +DMPK UCSF GRCh37 19 46281768 46281768 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 14 115 0 ENST00000343373.4:c.594G>A p.Arg198= p.R198= ENST00000343373 NM_001081563.1 198 cgG/cgA 0 +DMRTA2 UCSF GRCh37 1 50886967 50886967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 24 220 0 ENST00000404795.3:c.242C>T p.Ala81Val p.A81V ENST00000404795 NM_032110.2 81 gCc/gTc 0 +DMTF1 UCSF GRCh37 7 86822635 86822635 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 21 174 0 ENST00000394703.5:c.1616C>T p.Ala539Val p.A539V ENST00000394703 NM_021145.3 539 gCt/gTt 0 +DMXL1 UCSF GRCh37 5 118407301 118407301 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 20 161 0 ENST00000311085.8:c.37C>T p.Pro13Ser p.P13S ENST00000311085 NM_005509.4 13 Cct/Tct 0 +DNAH1 UCSF GRCh37 3 52386630 52386630 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 8 51 0 ENST00000420323.2:c.2934G>A p.Glu978= p.E978= ENST00000420323 NM_015512.4 978 gaG/gaA 0 +DNAH1 UCSF GRCh37 3 52398656 52398656 + splice_region_variant,synonymous_variant Splice_Region SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 48 140 1 ENST00000420323.2:c.5247T>C p.Asp1749= p.D1749= ENST00000420323 NM_015512.4 1749 gaT/gaC 0 +DNAH10 UCSF GRCh37 12 124413843 124413843 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 474 74 603 0 ENST00000409039.3:c.11974G>A p.Gly3992Arg p.G3992R ENST00000409039 NM_207437.3 3992 Ggg/Agg 0 +DNAH10 UCSF GRCh37 12 124311386 124311386 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 4 50 0 ENST00000409039.3:c.3978G>A p.Lys1326= p.K1326= ENST00000409039 NM_207437.3 1326 aaG/aaA 0 +DNAH2 UCSF GRCh37 17 7636501 7636501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 604 100 719 0 ENST00000572933.1:c.496C>T p.Pro166Ser p.P166S ENST00000572933 166 Ccc/Tcc 0 +DNAH2 UCSF GRCh37 17 7696469 7696469 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 274 48 460 0 ENST00000572933.1:c.7515G>A p.Trp2505Ter p.W2505* ENST00000572933 2505 tgG/tgA 0 +DNAH2 UCSF GRCh37 17 7663129 7663129 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 552 79 775 0 ENST00000572933.1:c.2658G>A p.Leu886= p.L886= ENST00000572933 886 ctG/ctA 0 +DNAH6 UCSF GRCh37 2 84774620 84774620 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 21 254 0 ENST00000389394.3:c.1070C>T p.Thr357Ile p.T357I ENST00000389394 NM_001370.1 357 aCa/aTa 0 +DNAH8 UCSF GRCh37 6 38840477 38840477 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 26 247 0 ENST00000359357.3:c.6505G>A p.Gly2169Ser p.G2169S ENST00000359357 2169 Ggc/Agc 0 +DNAH8 UCSF GRCh37 6 38690630 38690630 + upstream_gene_variant 5'Flank SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 43 0 ENST00000359357 0 +DNAJB1 UCSF GRCh37 19 14627575 14627575 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 16 113 0 ENST00000254322.2:c.495C>T p.Thr165= p.T165= ENST00000254322 NM_006145.1 165 acC/acT 0 +DNAJB7 UCSF GRCh37 22 41257988 41257988 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 19 183 0 ENST00000307221.4:c.11A>G p.Tyr4Cys p.Y4C ENST00000307221 NM_145174.1 4 tAc/tGc 0 +DNAJC2 UCSF GRCh37 7 102957322 102957322 + stop_gained Nonsense_Mutation SNP A A C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 39 133 0 ENST00000379263.3:c.1382T>G p.Leu461Ter p.L461* ENST00000379263 NM_014377.1 461 tTa/tGa 0 +DNAJC6 UCSF GRCh37 1 65855296 65855296 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 12 126 0 ENST00000371069.4:c.1454C>T p.Ser485Phe p.S485F ENST00000371069 NM_001256864.1 485 tCt/tTt 0 +DNASE1 UCSF GRCh37 16 3707321 3707321 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 8 47 0 ENST00000246949.5:c.683C>T p.Pro228Leu p.P228L ENST00000246949 NM_005223.3 228 cCc/cTc 0 +DNHD1 UCSF GRCh37 11 6540976 6540976 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 59 163 0 ENST00000254579.6:c.1539G>A p.Trp513Ter p.W513* ENST00000254579 NM_144666.2 513 tgG/tgA 0 +DNM2 UCSF GRCh37 19 10934513 10934513 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 301 35 308 0 ENST00000389253.4:c.1831G>A p.Glu611Lys p.E611K ENST00000389253 NM_001005361.2 611 Gaa/Aaa 0 +DOCK11 UCSF GRCh37 X 117707891 117707891 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 16 92 0 ENST00000276202.7:c.1299C>T p.Thr433= p.T433= ENST00000276202 NM_144658.3 433 acC/acT 0 +DOCK3 UCSF GRCh37 3 51112786 51112786 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 11 103 0 ENST00000266037.9:c.465-1G>A p.X155_splice ENST00000266037 NM_004947.4 0 +DOCK5 UCSF GRCh37 8 25168013 25168013 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 198 24 213 0 ENST00000276440.7:c.1283C>T p.Ala428Val p.A428V ENST00000276440 NM_024940.6 428 gCc/gTc 0 +DOK2 UCSF GRCh37 8 21767047 21767047 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 49 172 0 ENST00000276420.4:c.1014C>T p.Pro338= p.P338= ENST00000276420 NM_003974.2 338 ccC/ccT 0 +DOLPP1 UCSF GRCh37 9 131847825 131847825 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 32 94 0 ENST00000372546.4:c.391C>T p.Leu131= p.L131= ENST00000372546 NM_020438.4 131 Ctg/Ttg 0 +DPEP3 UCSF GRCh37 16 68012174 68012174 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 10 119 0 ENST00000268793.4:c.757C>T p.Pro253Ser p.P253S ENST00000268793 NM_022357.3 253 Cca/Tca 0 +DPF2 UCSF GRCh37 11 65113252 65113252 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 12 110 0 ENST00000528416.1:c.753C>T p.Ser251= p.S251= ENST00000528416 NM_006268.4 251 tcC/tcT 0 +DPP8 UCSF GRCh37 15 65777486 65777486 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 18 234 0 ENST00000341861.5:c.1016C>T p.Pro339Leu p.P339L ENST00000341861 NM_197960.2 339 cCt/cTt 0 +DPP9 UCSF GRCh37 19 4704019 4704019 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 11 99 0 ENST00000262960.9:c.648C>T p.Pro216= p.P216= ENST00000262960 NM_139159.4 216 ccC/ccT 0 +DRD1 UCSF GRCh37 5 174869973 174869973 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 12 156 0 ENST00000393752.2:c.130G>A p.Val44Ile p.V44I ENST00000393752 NM_000794.3 44 Gtc/Atc 0 +DROSHA UCSF GRCh37 5 31435970 31435970 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 19 67 0 ENST00000344624.3:c.2944G>A p.Val982Ile p.V982I ENST00000344624 982 Gtc/Atc 0 +DSCAM UCSF GRCh37 21 41496237 41496237 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 7 60 0 ENST00000400454.1:c.3581G>A p.Gly1194Asp p.G1194D ENST00000400454 NM_001271534.1 1194 gGt/gAt 0 +DSCAM UCSF GRCh37 21 41711201 41711201 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 20 186 0 ENST00000400454.1:c.1352G>A p.Gly451Asp p.G451D ENST00000400454 NM_001271534.1 451 gGc/gAc 0 +DSCAM UCSF GRCh37 21 41710220 41710220 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 25 250 0 ENST00000400454.1:c.1591C>T p.Pro531Ser p.P531S ENST00000400454 NM_001271534.1 531 Ccg/Tcg 0 +DSCAM UCSF GRCh37 21 41725552 41725552 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 18 111 0 ENST00000400454.1:c.774G>A p.Trp258Ter p.W258* ENST00000400454 NM_001271534.1 258 tgG/tgA 0 +DSG2 UCSF GRCh37 18 29121189 29121189 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 17 87 0 ENST00000261590.8:c.1913G>A p.Gly638Glu p.G638E ENST00000261590 NM_001943.3 638 gGa/gAa 0 +DST UCSF GRCh37 6 56334743 56334743 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 34 277 0 ENST00000244364.6:c.14620G>A p.Val4874Ile p.V4874I ENST00000244364 NM_015548.4 4874 Gta/Ata 0 +DSTYK UCSF GRCh37 1 205126440 205126440 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 24 237 0 ENST00000367162.3:c.2313G>A p.Gln771= p.Q771= ENST00000367162 NM_015375.2 771 caG/caA 0 +DTX1 UCSF GRCh37 12 113515352 113515352 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 22 213 0 ENST00000257600.3:c.383C>T p.Thr128Ile p.T128I ENST00000257600 NM_004416.2 128 aCc/aTc 0 +DUOXA1 UCSF GRCh37 15 45410176 45410176 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 5 71 0 ENST00000267803.4:c.1083G>A p.Gln361= p.Q361= ENST00000267803 NM_144565.3 361 caG/caA 0 +DUS4L UCSF GRCh37 7 107211613 107211613 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 8 52 0 ENST00000265720.3:c.140G>A p.Arg47Lys p.R47K ENST00000265720 NM_001270419.1 47 aGa/aAa 0 +DUS4L UCSF GRCh37 7 107217867 107217867 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 59 236 0 ENST00000265720.3:c.816G>A p.Gly272= p.G272= ENST00000265720 NM_001270419.1 272 ggG/ggA 0 +DUSP13 UCSF GRCh37 10 76854607 76854607 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 47 0 ENST00000372700.3:c.574G>A p.Val192Ile p.V192I ENST00000372700 NM_001007272.1 192 Gta/Ata 0 +DUSP6 UCSF GRCh37 12 89745677 89745677 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 263 30 358 0 ENST00000279488.7:c.140C>T p.Ser47Leu p.S47L ENST00000279488 NM_001946.2 47 tCg/tTg 0 +DVL1 UCSF GRCh37 1 1275467 1275467 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 6 44 0 ENST00000378891.5:c.860G>A p.Gly287Glu p.G287E ENST00000378891 NM_004421.2 287 gGg/gAg 0 +DVL3 UCSF GRCh37 3 183888396 183888396 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 56 452 1 ENST00000313143.3:c.2004G>A p.Met668Ile p.M668I ENST00000313143 NM_004423.3 668 atG/atA 0 +DVL3 UCSF GRCh37 3 183882976 183882976 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 27 171 0 ENST00000313143.3:c.675G>A p.Lys225= p.K225= ENST00000313143 NM_004423.3 225 aaG/aaA 0 +DYNC1H1 UCSF GRCh37 14 102452456 102452456 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 234 34 322 0 ENST00000360184.4:c.1894G>A p.Ala632Thr p.A632T ENST00000360184 NM_001376.4 632 Gct/Act 0 +DYNC2H1 UCSF GRCh37 11 103005056 103005056 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 25 185 0 ENST00000398093.3:c.2113G>A p.Val705Ile p.V705I ENST00000398093 705 Gtt/Att 0 +DYNC2H1 UCSF GRCh37 11 103107235 103107235 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 13 157 0 ENST00000398093.3:c.9786C>T p.Asp3262= p.D3262= ENST00000398093 3262 gaC/gaT 0 +DYSF UCSF GRCh37 2 71795384 71795384 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 23 235 1 ENST00000410020.3:c.2780G>A p.Gly927Asp p.G927D ENST00000410020 NM_001130987.1 927 gGc/gAc 0 +DYSF UCSF GRCh37 2 71766326 71766326 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 257 40 386 0 ENST00000410020.3:c.1533C>T p.Tyr511= p.Y511= ENST00000410020 NM_001130987.1 511 taC/taT 0 +DYX1C1 UCSF GRCh37 15 55790479 55790479 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 74 232 0 ENST00000321149.3:c.49G>A p.Val17Ile p.V17I ENST00000321149 NM_130810.3 17 Gtc/Atc 0 +DYX1C1 UCSF GRCh37 15 55790464 55790464 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 24 218 0 ENST00000321149.3:c.64C>T p.Pro22Ser p.P22S ENST00000321149 NM_130810.3 22 Ccc/Tcc 0 +E2F2 UCSF GRCh37 1 23848374 23848374 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 24 176 0 ENST00000361729.2:c.533G>A p.Gly178Asp p.G178D ENST00000361729 NM_004091.3 178 gGc/gAc 0 +E2F3 UCSF GRCh37 6 20490487 20490487 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 28 262 0 ENST00000346618.3:c.1224G>A p.Gln408= p.Q408= ENST00000346618 NM_001949.4 408 caG/caA 0 +E2F7 UCSF GRCh37 12 77421803 77421803 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 29 268 0 ENST00000322886.7:c.2000G>A p.Gly667Glu p.G667E ENST00000322886 NM_203394.2 667 gGa/gAa 0 +E2F7 UCSF GRCh37 12 77423701 77423701 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 10 57 0 ENST00000322886.7:c.1794G>A p.Glu598= p.E598= ENST00000322886 NM_203394.2 598 gaG/gaA 0 +EARS2 UCSF GRCh37 16 23540917 23540917 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 10 114 0 ENST00000449606.1:c.1258G>A p.Val420Ile p.V420I ENST00000449606 NM_001083614.1 420 Gta/Ata 0 +EARS2 UCSF GRCh37 16 23563625 23563625 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 36 116 0 ENST00000449606.1:c.140G>A p.Gly47Asp p.G47D ENST00000449606 NM_001083614.1 47 gGc/gAc 0 +EBAG9 UCSF GRCh37 8 110573142 110573142 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 20 206 0 ENST00000337573.5:c.505G>A p.Ala169Thr p.A169T ENST00000337573 NM_004215.4 169 Gca/Aca 0 +ECM2 UCSF GRCh37 9 95277008 95277008 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 303 47 436 0 ENST00000344604.5:c.959G>A p.Cys320Tyr p.C320Y ENST00000344604 NM_001393.3 320 tGc/tAc 0 +EDC3 UCSF GRCh37 15 74925151 74925151 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 65 180 0 ENST00000315127.4:c.1329C>T p.Asp443= p.D443= ENST00000315127 NM_025083.3 443 gaC/gaT 0 +EEF2 UCSF GRCh37 19 3979880 3979880 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 7 52 0 ENST00000309311.6:c.1531G>A p.Ala511Thr p.A511T ENST00000309311 NM_001961.3 511 Gcc/Acc 0 +EEFSEC UCSF GRCh37 3 128060196 128060196 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 20 211 0 ENST00000254730.6:c.907G>A p.Val303Met p.V303M ENST00000254730 NM_021937.3 303 Gtg/Atg 0 +EFCAB5 UCSF GRCh37 17 28380852 28380852 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 338 47 486 0 ENST00000394835.3:c.1880G>A p.Gly627Glu p.G627E ENST00000394835 NM_198529.3 627 gGa/gAa 0 +EFEMP1 UCSF GRCh37 2 56094295 56094295 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 12 140 0 ENST00000394555.2:c.1395G>A p.Leu465= p.L465= ENST00000394555 NM_001039348.2 465 ctG/ctA 0 +EFNB1 UCSF GRCh37 X 68058563 68058563 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 7 72 0 ENST00000204961.4:c.232C>T p.Leu78= p.L78= ENST00000204961 NM_004429.4 78 Ctg/Ttg 0 +EFNB3 UCSF GRCh37 17 7608984 7608984 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 19 141 0 ENST00000226091.2:c.68G>A p.Gly23Glu p.G23E ENST00000226091 NM_001406.3 23 gGg/gAg 0 +EGF UCSF GRCh37 4 110884380 110884380 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 15 87 0 ENST00000265171.5:c.1364G>A p.Ser455Asn p.S455N ENST00000265171 NM_001963.4 455 aGc/aAc 0 +EGFL7 UCSF GRCh37 9 139564675 139564675 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 19 94 1 ENST00000308874.7:c.464C>T p.Thr155Ile p.T155I ENST00000308874 155 aCc/aTc 0 +EGR2 UCSF GRCh37 10 64574184 64574184 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 7 70 0 ENST00000242480.3:c.214G>A p.Asp72Asn p.D72N ENST00000242480 NM_001136177.1 72 Gat/Aat 0 +EHHADH UCSF GRCh37 3 184922287 184922287 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 20 116 0 ENST00000231887.3:c.827G>A p.Arg276Lys p.R276K ENST00000231887 NM_001166415.1 276 aGg/aAg 0 +EHHADH UCSF GRCh37 3 184922469 184922469 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 37 230 0 ENST00000231887.3:c.645G>A p.Glu215= p.E215= ENST00000231887 NM_001166415.1 215 gaG/gaA 0 +EHMT2 UCSF GRCh37 6 31860229 31860229 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 38 123 0 ENST00000375537.4:c.819C>T p.Tyr273= p.Y273= ENST00000375537 NM_006709.3 273 taC/taT 0 +EIF2B4 UCSF GRCh37 2 27590049 27590049 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 31 268 0 ENST00000451130.2:c.965C>T p.Ala322Val p.A322V ENST00000451130 NM_172195.3 322 gCa/gTa 0 +EIF5A UCSF GRCh37 17 7210382 7210382 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 39 78 0 ENST00000336452.7:c.17G>A p.Gly6Glu p.G6E ENST00000336452 NM_001143760.1 6 gGg/gAg 0 +ELF5 UCSF GRCh37 11 34515099 34515099 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 22 251 0 ENST00000312319.2:c.312G>A p.Gln104= p.Q104= ENST00000312319 NM_001243081.1 104 caG/caA 0 +ELMO2 UCSF GRCh37 20 44999118 44999118 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 315 49 415 0 ENST00000290246.6:c.1848C>T p.Pro616= p.P616= ENST00000290246 NM_133171.3 616 ccC/ccT 0 +ELMO3 UCSF GRCh37 16 67237579 67237579 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 40 376 0 ENST00000393997.2:c.2121G>A p.Trp707Ter p.W707* ENST00000393997 NM_024712.3 707 tgG/tgA 0 +ELP3 UCSF GRCh37 8 27987165 27987165 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 22 93 0 ENST00000256398.8:c.764C>T p.Ala255Val p.A255V ENST00000256398 NM_018091.5 255 gCt/gTt 0 +EMILIN3 UCSF GRCh37 20 39989948 39989948 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 12 119 0 ENST00000332312.3:c.2261C>T p.Ala754Val p.A754V ENST00000332312 NM_052846.1 754 gCc/gTc 0 +EML3 UCSF GRCh37 11 62371283 62371283 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 49 436 1 ENST00000394773.2:c.2175C>T p.His725= p.H725= ENST00000394773 NM_153265.2 725 caC/caT 0 +EMR3 UCSF GRCh37 19 14755077 14755077 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 10 27 0 ENST00000253673.5:c.893G>A p.Ser298Asn p.S298N ENST00000253673 NM_032571.3 298 aGt/aAt 0 +ENPEP UCSF GRCh37 4 111430940 111430940 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 17 127 0 ENST00000265162.5:c.1171G>A p.Val391Ile p.V391I ENST00000265162 NM_001977.3 391 Gtt/Att 0 +ENTPD5 UCSF GRCh37 14 74436818 74436818 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 12 189 0 ENST00000334696.6:c.1095C>T p.Asn365= p.N365= ENST00000334696 NM_001249.2 365 aaC/aaT 0 +ENTPD8 UCSF GRCh37 9 140332632 140332632 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 5 42 0 ENST00000371506.2:c.106C>T p.Leu36Phe p.L36F ENST00000371506 NM_001033113.1 36 Ctc/Ttc 0 +EOMES UCSF GRCh37 3 27761734 27761734 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 15 133 0 ENST00000295743.4:c.964G>A p.Ala322Thr p.A322T ENST00000295743 NM_005442.3 322 Gcg/Acg 0 +EPC2 UCSF GRCh37 2 149542240 149542240 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 313 41 450 0 ENST00000258484.6:c.2021C>T p.Thr674Ile p.T674I ENST00000258484 NM_015630.3 674 aCc/aTc 0 +EPC2 UCSF GRCh37 2 149526793 149526793 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 23 210 0 ENST00000258484.6:c.1214G>A p.Gly405Glu p.G405E ENST00000258484 NM_015630.3 405 gGa/gAa 0 +EPHA5 UCSF GRCh37 4 66467870 66467870 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 28 242 0 ENST00000273854.3:c.399C>T p.Thr133= p.T133= ENST00000273854 NM_004439.5 133 acC/acT 0 +EPHA7 UCSF GRCh37 6 94124467 94124470 + protein_altering_variant In_Frame_Del DEL TTAG TTAG A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 0 ENST00000369303.4:c.113_116delinsT p.Ser38_Lys39delinsLeu p.S38_K39delinsL ENST00000369303 NM_004440.3 38 tCTAAa/tTa 0 +EPHB3 UCSF GRCh37 3 184298276 184298276 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 22 170 0 ENST00000330394.2:c.2259C>T p.Asn753= p.N753= ENST00000330394 NM_004443.3 753 aaC/aaT 0 +EPHB4 UCSF GRCh37 7 100402857 100402857 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 101 342 1 ENST00000358173.3:c.2765G>A p.Gly922Glu p.G922E ENST00000358173 NM_004444.4 922 gGa/gAa 0 +EPHB6 UCSF GRCh37 7 142566777 142566777 + synonymous_variant Silent SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 39 107 0 ENST00000392957.2:c.2334A>T p.Gly778= p.G778= ENST00000392957 NM_004445.4 778 ggA/ggT 0 +EPM2AIP1 UCSF GRCh37 3 37033028 37033028 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 401 57 586 0 ENST00000322716.5:c.1541C>T p.Thr514Ile p.T514I ENST00000322716 NM_014805.3 514 aCt/aTt 0 +EPOR UCSF GRCh37 19 11494794 11494794 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 15 116 0 ENST00000222139.6:c.90C>T p.Leu30= p.L30= ENST00000222139 NM_000121.3 30 ctC/ctT 0 +EPS15 UCSF GRCh37 1 51829613 51829613 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 17 195 0 ENST00000371733.3:c.2284G>A p.Val762Ile p.V762I ENST00000371733 NM_001981.2 762 Gtc/Atc 0 +EPS15L1 UCSF GRCh37 19 16539545 16539545 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 9 89 0 ENST00000455140.2:c.526G>A p.Asp176Asn p.D176N ENST00000455140 NM_001258374.1 176 Gat/Aat 0 +ERBB2 UCSF GRCh37 17 37883081 37883081 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 88 10 97 0 ENST00000269571.5:c.2984G>A p.Gly995Asp p.G995D ENST00000269571 995 gGc/gAc 0 +ERBB3 UCSF GRCh37 12 56489094 56489094 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 25 156 0 ENST00000267101.3:c.1913G>A p.Gly638Asp p.G638D ENST00000267101 NM_001982.3 638 gGc/gAc 0 +ERCC2 UCSF GRCh37 19 45872002 45872002 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 22 241 0 ENST00000391945.4:c.247-1G>A p.X83_splice ENST00000391945 NM_000400.3 0 +ERCC6L UCSF GRCh37 X 71427460 71427460 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 47 177 0 ENST00000334463.3:c.1157C>T p.Ser386Phe p.S386F ENST00000334463 NM_017669.2 386 tCt/tTt 0 +ERG UCSF GRCh37 21 39775600 39775600 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 23 176 1 ENST00000288319.7:c.420G>A p.Arg140= p.R140= ENST00000288319 NM_182918.3 140 cgG/cgA 0 +ERN1 UCSF GRCh37 17 62130215 62130215 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 11 79 0 ENST00000433197.3:c.2178C>T p.Ser726= p.S726= ENST00000433197 NM_001433.3 726 agC/agT 0 +ESF1 UCSF GRCh37 20 13740436 13740438 + inframe_deletion In_Frame_Del DEL TTC TTC - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 0 ENST00000202816.1:c.1729_1731del p.Glu577del p.E577del ENST00000202816 NM_001276380.1 577 GAA/- 0 +ESPN UCSF GRCh37 1 6500850 6500850 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 5 20 0 ENST00000377828.1:c.840C>T p.Ala280= p.A280= ENST00000377828 NM_031475.2 280 gcC/gcT 0 +ESR1 UCSF GRCh37 6 152129195 152129195 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 75 553 0 ENST00000206249.3:c.148G>A p.Ala50Thr p.A50T ENST00000206249 NM_000125.3 50 Gcc/Acc 0 +ETV5 UCSF GRCh37 3 185797664 185797664 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 4 32 0 ENST00000306376.5:c.592C>T p.His198Tyr p.H198Y ENST00000306376 NM_004454.2 198 Cat/Tat 0 +EVPL UCSF GRCh37 17 74006574 74006574 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 23 231 0 ENST00000301607.3:c.2712C>T p.Ser904= p.S904= ENST00000301607 NM_001988.2 904 tcC/tcT 0 +EVX1 UCSF GRCh37 7 27285969 27285969 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 73 250 0 ENST00000496902.4:c.1149C>T p.Thr383= p.T383= ENST00000496902 383 acC/acT 0 +EXD2 UCSF GRCh37 14 69704378 69704378 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 238 41 338 0 ENST00000409018.3:c.1379C>T p.Thr460Ile p.T460I ENST00000409018 NM_001193361.1 460 aCc/aTc 0 +EXOC5 UCSF GRCh37 14 57675449 57675449 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 10 69 0 ENST00000413566.2:c.2005G>A p.Asp669Asn p.D669N ENST00000413566 NM_006544.3 669 Gat/Aat 0 +EXOSC1 UCSF GRCh37 10 99200978 99200978 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 12 196 0 ENST00000370902.3:c.261C>T p.Ile87= p.I87= ENST00000370902 NM_016046.3 87 atC/atT 0 +EXOSC2 UCSF GRCh37 9 133570909 133570909 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 25 179 0 ENST00000372358.5:c.153G>A p.Lys51= p.K51= ENST00000372358 51 aaG/aaA 0 +F12 UCSF GRCh37 5 176829423 176829423 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 19 147 0 ENST00000253496.3:c.1718C>T p.Ala573Val p.A573V ENST00000253496 NM_000505.3 573 gCt/gTt 0 +F8 UCSF GRCh37 X 154132241 154132241 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 49 191 0 ENST00000360256.4:c.5938C>T p.His1980Tyr p.H1980Y ENST00000360256 NM_000132.3 1980 Cat/Tat 0 +F9 UCSF GRCh37 X 138644119 138644119 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 17 112 0 ENST00000218099.2:c.1275A>T p.Leu425Phe p.L425F ENST00000218099 NM_000133.3 425 ttA/ttT 0 +FAF2 UCSF GRCh37 5 175925919 175925919 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 20 102 0 ENST00000261942.6:c.844G>A p.Glu282Lys p.E282K ENST00000261942 NM_014613.2 282 Gaa/Aaa 0 +FAF2 UCSF GRCh37 5 175923506 175923506 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 22 190 0 ENST00000261942.6:c.681G>A p.Glu227= p.E227= ENST00000261942 NM_014613.2 227 gaG/gaA 0 +FAIM UCSF GRCh37 3 138340249 138340249 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 65 0 ENST00000338446.4:c.81C>T p.Ser27= p.S27= ENST00000338446 NM_001033030.1 27 agC/agT 0 +FAM111B UCSF GRCh37 11 58892470 58892470 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 29 292 0 ENST00000343597.3:c.900G>A p.Gln300= p.Q300= ENST00000343597 NM_198947.3 300 caG/caA 0 +FAM120A UCSF GRCh37 9 96214591 96214591 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 23 142 0 ENST00000277165.6:c.394C>T p.Pro132Ser p.P132S ENST00000277165 NM_014612.3 132 Ccg/Tcg 0 +FAM123B UCSF GRCh37 X 63412254 63412254 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 32 152 0 ENST00000330258.3:c.913G>A p.Val305Met p.V305M ENST00000330258 NM_152424.3 305 Gtg/Atg 0 +FAM124A UCSF GRCh37 13 51854925 51854925 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 24 195 0 ENST00000280057.6:c.1282G>A p.Ala428Thr p.A428T ENST00000280057 NM_145019.3 428 Gca/Aca 0 +FAM125B UCSF GRCh37 9 129102882 129102882 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 27 189 0 ENST00000361171.3:c.177G>A p.Arg59= p.R59= ENST00000361171 NM_033446.2 59 cgG/cgA 0 +FAM129B UCSF GRCh37 9 130270371 130270371 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 14 121 0 ENST00000373312.3:c.1542+1G>A p.X514_splice ENST00000373312 NM_022833.2 0 +FAM13A UCSF GRCh37 4 89658648 89658648 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 171 30 231 0 ENST00000264344.5:c.2621C>T p.Thr874Ile p.T874I ENST00000264344 NM_014883.3 874 aCt/aTt 0 +FAM13A UCSF GRCh37 4 89950686 89950686 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 20 136 0 ENST00000264344.5:c.142C>T p.Leu48Phe p.L48F ENST00000264344 NM_014883.3 48 Ctt/Ttt 0 +FAM150A UCSF GRCh37 8 53477802 53477802 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 7 30 0 ENST00000358543.4:c.15G>A p.Lys5= p.K5= ENST00000358543 NM_207413.3 5 aaG/aaA 0 +FAM159B UCSF GRCh37 5 63986544 63986544 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 19 139 0 ENST00000389074.5:c.94G>A p.Ala32Thr p.A32T ENST00000389074 NM_001164442.1 32 Gcg/Acg 0 +FAM161A UCSF GRCh37 2 62054254 62054254 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 27 255 0 ENST00000404929.1:c.1991C>T p.Thr664Ile p.T664I ENST00000404929 NM_001201543.1 664 aCt/aTt 0 +FAM169A UCSF GRCh37 5 74137408 74137408 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 17 91 0 ENST00000389156.4:c.94C>T p.Pro32Ser p.P32S ENST00000389156 NM_015566.2 32 Cct/Tct 0 +FAM178B UCSF GRCh37 2 97637851 97637851 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 8 78 0 ENST00000490605.2:c.351C>T p.Phe117= p.F117= ENST00000490605 117 ttC/ttT 0 +FAM179B UCSF GRCh37 14 45478150 45478150 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 22 194 0 ENST00000361577.3:c.2939C>T p.Ala980Val p.A980V ENST00000361577 NM_015091.2 980 gCa/gTa 0 +FAM184A UCSF GRCh37 6 119345658 119345658 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 23 261 0 ENST00000338891.7:c.480G>A p.Glu160= p.E160= ENST00000338891 NM_024581.4 160 gaG/gaA 0 +FAM184B UCSF GRCh37 4 17654508 17654508 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 12 125 0 ENST00000265018.3:c.2136G>A p.Arg712= p.R712= ENST00000265018 NM_015688.1 712 agG/agA 0 +FAM193A UCSF GRCh37 4 2695364 2695364 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 230 40 336 1 ENST00000324666.5:c.1982C>T p.Ala661Val p.A661V ENST00000324666 NM_001256666.1 661 gCc/gTc 0 +FAM19A1 UCSF GRCh37 3 68466434 68466434 + synonymous_variant Silent SNP A A C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 9 29 0 ENST00000478136.1:c.123A>C p.Gly41= p.G41= ENST00000478136 NM_213609.3 41 ggA/ggC 0 +FAM20A UCSF GRCh37 17 66551789 66551789 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 13 113 0 ENST00000592554.1:c.500G>A p.Gly167Asp p.G167D ENST00000592554 NM_001243746.1 167 gGt/gAt 0 +FAM40A UCSF GRCh37 1 110582044 110582044 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 15 152 0 ENST00000369795.3:c.488C>T p.Ala163Val p.A163V ENST00000369795 NM_033088.3 163 gCa/gTa 0 +FAM69A UCSF GRCh37 1 93309726 93309726 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 25 154 0 ENST00000370310.4:c.501C>T p.Leu167= p.L167= ENST00000370310 NM_001006605.4 167 ctC/ctT 0 +FAM69B UCSF GRCh37 9 139617667 139617667 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 71 0 ENST00000371692.4:c.737C>T p.Pro246Leu p.P246L ENST00000371692 NM_152421.3 246 cCc/cTc 0 +FAM71E1 UCSF GRCh37 19 50979499 50979499 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 27 265 0 ENST00000595790.1:c.147C>T p.Leu49= p.L49= ENST00000595790 NM_138411.1 49 ctC/ctT 0 +FAM83G UCSF GRCh37 17 18874698 18874698 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 18 179 0 ENST00000388995.6:c.2446G>A p.Ala816Thr p.A816T ENST00000388995 816 Gcc/Acc 0 +FAM89A UCSF GRCh37 1 231175885 231175885 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 9 38 0 ENST00000366654.4:c.73C>T p.Pro25Ser p.P25S ENST00000366654 NM_198552.2 25 Ccc/Tcc 0 +FANCL UCSF GRCh37 2 58390002 58390002 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 34 0 ENST00000402135.3:c.917C>T p.Ser306Phe p.S306F ENST00000402135 NM_001114636.1 306 tCt/tTt 0 +FAR2 UCSF GRCh37 12 29486702 29486702 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 16 168 0 ENST00000536681.3:c.1523G>A p.Arg508Lys p.R508K ENST00000536681 NM_001271783.1 508 aGa/aAa 0 +FASN UCSF GRCh37 17 80037425 80037425 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 29 208 0 ENST00000306749.2:c.7206C>T p.Asp2402= p.D2402= ENST00000306749 NM_004104.4 2402 gaC/gaT 0 +FASTKD1 UCSF GRCh37 2 170393787 170393787 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 11 178 0 ENST00000453153.2:c.2138G>A p.Gly713Glu p.G713E ENST00000453153 NM_024622.4 713 gGa/gAa 0 +FAT1 UCSF GRCh37 4 187542680 187542680 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 20 235 0 ENST00000441802.2:c.5060G>A p.Gly1687Glu p.G1687E ENST00000441802 NM_005245.3 1687 gGg/gAg 0 +FAT2 UCSF GRCh37 5 150886790 150886790 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 254 37 380 0 ENST00000261800.5:c.12442C>T p.Leu4148Phe p.L4148F ENST00000261800 NM_001447.2 4148 Ctc/Ttc 0 +FAT2 UCSF GRCh37 5 150908849 150908849 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 15 64 0 ENST00000261800.5:c.9916A>G p.Thr3306Ala p.T3306A ENST00000261800 NM_001447.2 3306 Aca/Gca 0 +FAT3 UCSF GRCh37 11 92533914 92533914 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 8 61 0 ENST00000298047.6:c.7735G>A p.Gly2579Arg p.G2579R ENST00000298047 2579 Ggg/Agg 0 +FAT4 UCSF GRCh37 4 126355424 126355424 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 43 375 0 ENST00000394329.3:c.7043G>A p.Gly2348Glu p.G2348E ENST00000394329 NM_024582.4 2348 gGa/gAa 0 +FAT4 UCSF GRCh37 4 126241448 126241448 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 243 87 688 0 ENST00000394329.3:c.3882C>T p.Pro1294= p.P1294= ENST00000394329 NM_024582.4 1294 ccC/ccT 0 +FBN3 UCSF GRCh37 19 8174197 8174197 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 11 68 0 ENST00000600128.1:c.4532G>A p.Gly1511Glu p.G1511E ENST00000600128 1511 gGa/gAa 0 +FBP1 UCSF GRCh37 9 97372255 97372255 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 9 82 0 ENST00000415431.1:c.515C>T p.Thr172Ile p.T172I ENST00000415431 NM_001127628.1 172 aCc/aTc 0 +FBXL14 UCSF GRCh37 12 1702849 1702849 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 57 124 0 ENST00000339235.3:c.384G>A p.Lys128= p.K128= ENST00000339235 NM_152441.2 128 aaG/aaA 0 +FBXL15 UCSF GRCh37 10 104181808 104181808 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 22 95 0 ENST00000224862.3:c.472C>T p.Leu158= p.L158= ENST00000224862 NM_024326.3 158 Ctg/Ttg 0 +FBXO24 UCSF GRCh37 7 100190601 100190601 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 10 43 0 ENST00000427939.2:c.868G>A p.Val290Ile p.V290I ENST00000427939 NM_012172.4 290 Gtt/Att 0 +FBXO38 UCSF GRCh37 5 147785859 147785859 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 39 379 0 ENST00000394370.3:c.770G>A p.Gly257Asp p.G257D ENST00000394370 257 gGc/gAc 0 +FBXO40 UCSF GRCh37 3 121340471 121340471 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 207 26 312 0 ENST00000338040.4:c.195C>T p.Cys65= p.C65= ENST00000338040 NM_016298.3 65 tgC/tgT 0 +FBXO41 UCSF GRCh37 2 73496421 73496421 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 11 97 0 ENST00000521871.1:c.338C>T p.Ala113Val p.A113V ENST00000521871 113 gCt/gTt 0 +FBXO8 UCSF GRCh37 4 175158624 175158624 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 34 285 0 ENST00000393674.2:c.899G>A p.Ser300Asn p.S300N ENST00000393674 NM_012180.2 300 aGt/aAt 0 +FBXW11 UCSF GRCh37 5 171337700 171337700 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 17 148 0 ENST00000265094.5:c.249G>A p.Trp83Ter p.W83* ENST00000265094 NM_012300.2 83 tgG/tgA 0 +FBXW7 UCSF GRCh37 4 153303474 153303474 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 15 206 0 ENST00000281708.4:c.501+28981G>A *167* ENST00000281708 NM_033632.3 0 +FCGBP UCSF GRCh37 19 40362965 40362965 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 17 118 0 ENST00000221347.6:c.15105G>A p.Val5035= p.V5035= ENST00000221347 NM_003890.2 5035 gtG/gtA 0 +FDX1L UCSF GRCh37 19 10426655 10426655 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 30 232 0 ENST00000393708.3:c.18C>T p.Ala6= p.A6= ENST00000393708 NM_001031734.2 6 gcC/gcT 0 +FER1L5 UCSF GRCh37 2 97363883 97363883 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 14 169 0 ENST00000397978.2:n.657G>A *219* ENST00000397978 0 +FES UCSF GRCh37 15 91433429 91433429 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 10 96 0 ENST00000328850.3:c.1157C>T p.Thr386Ile p.T386I ENST00000328850 NM_002005.3 386 aCc/aTc 0 +FFAR1 UCSF GRCh37 19 35843297 35843297 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 10 100 0 ENST00000246553.2:c.843G>A p.Arg281= p.R281= ENST00000246553 NM_005303.2 281 agG/agA 0 +FGD2 UCSF GRCh37 6 36990014 36990014 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 15 124 0 ENST00000274963.8:c.1327-1G>A p.X443_splice ENST00000274963 NM_173558.3 0 +FGD4 UCSF GRCh37 12 32764155 32764155 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 26 187 0 ENST00000427716.2:c.1276G>A p.Glu426Lys p.E426K ENST00000427716 NM_139241.2 426 Gaa/Aaa 0 +FHAD1 UCSF GRCh37 1 15639596 15639596 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 12 80 0 ENST00000375995.3:c.201G>A p.Glu67= p.E67= ENST00000375995 67 gaG/gaA 0 +FIGNL2 UCSF GRCh37 12 52214542 52214542 + non_coding_transcript_exon_variant RNA SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 15 151 0 ENST00000564840.1:n.1658C>T *553* ENST00000564840 0 +FILIP1L UCSF GRCh37 3 99569857 99569857 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 34 365 0 ENST00000354552.3:c.663G>A p.Lys221= p.K221= ENST00000354552 NM_182909.2 221 aaG/aaA 0 +FIP1L1 UCSF GRCh37 4 54319155 54319155 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 14 105 0 ENST00000337488.6:c.1354G>A p.Asp452Asn p.D452N ENST00000337488 NM_030917.3 452 Gac/Aac 0 +FKBP15 UCSF GRCh37 9 115935780 115935780 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 12 152 0 ENST00000238256.3:c.2485G>A p.Ala829Thr p.A829T ENST00000238256 NM_015258.1 829 Gca/Aca 0 +FKBP5 UCSF GRCh37 6 35545001 35545001 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 21 191 0 ENST00000536438.1:c.1036C>T p.Leu346= p.L346= ENST00000536438 NM_001145775.1 346 Ctg/Ttg 0 +FLG UCSF GRCh37 1 152286765 152286765 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 255 36 463 0 ENST00000368799.1:c.597G>A p.Arg199= p.R199= ENST00000368799 NM_002016.1 199 agG/agA 0 +FLG UCSF GRCh37 1 152280705 152280705 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 31 394 0 ENST00000368799.1:c.6657C>T p.Ser2219= p.S2219= ENST00000368799 NM_002016.1 2219 agC/agT 0 +FLJ22184 UCSF GRCh37 19 7934003 7934003 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 18 70 0 ENST00000539422.1:c.3957C>T p.Ile1319= p.I1319= ENST00000539422 NM_001190467.1 1319 atC/atT 0 +FLNB UCSF GRCh37 3 58092550 58092550 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 292 177 518 0 ENST00000490882.1:c.1891C>T p.Pro631Ser p.P631S ENST00000490882 NM_001164317.1 631 Ccg/Tcg 0 +FLNC UCSF GRCh37 7 128478320 128478320 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 269 38 261 0 ENST00000325888.8:c.1048-1G>A p.X350_splice ENST00000325888 NM_001458.4 0 +FLT3LG UCSF GRCh37 19 49983661 49983661 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 13 100 0 ENST00000594009.1:c.588C>T p.Leu196= p.L196= ENST00000594009 NM_001204503.1 196 ctC/ctT 0 +FLVCR1 UCSF GRCh37 1 213032485 213032485 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 47 0 ENST00000366971.4:c.691C>T p.Pro231Ser p.P231S ENST00000366971 NM_014053.3 231 Ccc/Tcc 0 +FLYWCH1 UCSF GRCh37 16 2988390 2988390 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 23 167 0 ENST00000416288.2:c.1980C>T p.Asp660= p.D660= ENST00000416288 NM_032296.2 660 gaC/gaT 0 +FMO5 UCSF GRCh37 1 146673066 146673066 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 9 105 0 ENST00000254090.4:c.851C>T p.Thr284Ile p.T284I ENST00000254090 NM_001461.3 284 aCc/aTc 0 +FMOD UCSF GRCh37 1 203317066 203317066 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 16 108 0 ENST00000354955.4:c.333C>T p.Tyr111= p.Y111= ENST00000354955 NM_002023.4 111 taC/taT 0 +FNDC8 UCSF GRCh37 17 33454374 33454374 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 47 314 0 ENST00000158009.5:c.523G>A p.Val175Ile p.V175I ENST00000158009 NM_017559.2 175 Gtt/Att 0 +FOXC1 UCSF GRCh37 6 1610723 1610723 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 7 27 0 ENST00000380874.2:c.43G>A p.Val15Met p.V15M ENST00000380874 NM_001453.2 15 Gtg/Atg 0 +FOXE1 UCSF GRCh37 9 100616951 100616951 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 14 102 0 ENST00000375123.3:c.755C>T p.Ala252Val p.A252V ENST00000375123 NM_004473.3 252 gCc/gTc 0 +FOXM1 UCSF GRCh37 12 2983270 2983270 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 11 106 0 ENST00000342628.2:c.375C>T p.Thr125= p.T125= ENST00000342628 NM_202002.2 125 acC/acT 0 +FOXP1 UCSF GRCh37 3 71008464 71008464 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 328 55 478 0 ENST00000318789.4:c.1968C>T p.Asn656= p.N656= ENST00000318789 NM_032682.5 656 aaC/aaT 0 +FRAS1 UCSF GRCh37 4 79295343 79295343 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 5 43 0 ENST00000264895.6:c.3089C>T p.Ala1030Val p.A1030V ENST00000264895 NM_025074.6 1030 gCc/gTc 0 +FRAS1 UCSF GRCh37 4 79334210 79334210 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 12 128 0 ENST00000264895.6:c.4396G>A p.Val1466Met p.V1466M ENST00000264895 NM_025074.6 1466 Gtg/Atg 0 +FRAS1 UCSF GRCh37 4 79461764 79461764 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 13 100 0 ENST00000264895.6:c.11525G>A p.Arg3842His p.R3842H ENST00000264895 NM_025074.6 3842 cGc/cAc 0 +FRMD7 UCSF GRCh37 X 131212018 131212018 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 18 126 0 ENST00000298542.4:c.2027G>A p.Arg676Lys p.R676K ENST00000298542 NM_194277.2 676 aGa/aAa 0 +FRS3 UCSF GRCh37 6 41738438 41738438 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 32 184 0 ENST00000373018.3:c.1398G>A p.Met466Ile p.M466I ENST00000373018 NM_006653.4 466 atG/atA 0 +FSD2 UCSF GRCh37 15 83449004 83449004 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 7 39 0 ENST00000334574.8:c.982G>A p.Ala328Thr p.A328T ENST00000334574 328 Gct/Act 0 +FSIP1 UCSF GRCh37 15 39910257 39910257 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 16 266 0 ENST00000350221.3:c.1378G>A p.Val460Ile p.V460I ENST00000350221 NM_152597.4 460 Gtc/Atc 0 +FTSJ3 UCSF GRCh37 17 61903936 61903936 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 8 59 0 ENST00000427159.2:c.164C>T p.Pro55Leu p.P55L ENST00000427159 NM_017647.3 55 cCa/cTa 0 +FURIN UCSF GRCh37 15 91423126 91423126 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 13 119 0 ENST00000268171.3:c.1288G>A p.Asp430Asn p.D430N ENST00000268171 NM_002569.2 430 Gac/Aac 0 +FUT5 UCSF GRCh37 19 5867208 5867208 + missense_variant Missense_Mutation SNP C C T snp132_rs61731581 P24_Rec2 Untested WXS Illumina HiSeq 60 13 67 0 ENST00000252675.5:c.529G>A p.Asp177Asn p.D177N ENST00000252675 177 Gac/Aac 0 +FUT9 UCSF GRCh37 6 96651405 96651405 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 206 24 269 0 ENST00000302103.5:c.374G>A p.Arg125Lys p.R125K ENST00000302103 NM_006581.3 125 aGg/aAg 0 +FXN UCSF GRCh37 9 71668084 71668084 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 7 65 0 ENST00000377270.3:c.292C>T p.Leu98= p.L98= ENST00000377270 NM_000144.4 98 Cta/Tta 0 +FZD10 UCSF GRCh37 12 130648588 130648588 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 23 234 0 ENST00000229030.4:c.1101C>T p.Ile367= p.I367= ENST00000229030 367 atC/atT 0 +G3BP2 UCSF GRCh37 4 76571553 76571553 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 19 273 0 ENST00000359707.4:c.1145C>T p.Ser382Phe p.S382F ENST00000359707 NM_203505.2 382 tCt/tTt 0 +GABBR1 UCSF GRCh37 6 29599359 29599359 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 7 60 0 ENST00000377034.4:c.103C>T p.Pro35Ser p.P35S ENST00000377034 NM_001470.2 35 Ccg/Tcg 0 +GABRR1 UCSF GRCh37 6 89888600 89888600 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 206 33 272 0 ENST00000454853.2:c.1329C>T p.Ser443= p.S443= ENST00000454853 NM_001256704.1 443 agC/agT 0 +GALNT10 UCSF GRCh37 5 153570543 153570543 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 8 51 0 ENST00000297107.6:c.117C>T p.Thr39= p.T39= ENST00000297107 NM_198321.3 39 acC/acT 0 +GALNT5 UCSF GRCh37 2 158115992 158115992 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 10 94 0 ENST00000259056.4:c.1398C>T p.Val466= p.V466= ENST00000259056 NM_014568.1 466 gtC/gtT 0 +GALNT7 UCSF GRCh37 4 174169194 174169194 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 3 42 0 ENST00000265000.4:c.190G>A p.Asp64Asn p.D64N ENST00000265000 NM_017423.2 64 Gac/Aac 0 +GALNTL1 UCSF GRCh37 14 69814638 69814638 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 20 185 0 ENST00000337827.4:c.1458C>T p.Cys486= p.C486= ENST00000337827 NM_020692.2 486 tgC/tgT 0 +GALNTL2 UCSF GRCh37 3 16237308 16237308 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 9 20 0 ENST00000339732.5:c.581G>A p.Ser194Asn p.S194N ENST00000339732 NM_054110.4 194 aGc/aAc 0 +GANAB UCSF GRCh37 11 62402333 62402333 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 26 162 0 ENST00000346178.4:c.520G>A p.Gly174Arg p.G174R ENST00000346178 NM_198335.3 174 Gga/Aga 0 +GATA1 UCSF GRCh37 X 48650557 48650557 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 17 192 0 ENST00000376670.3:c.527C>T p.Thr176Ile p.T176I ENST00000376670 NM_002049.3 176 aCc/aTc 0 +GBAS UCSF GRCh37 7 56049253 56049253 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 4 38 0 ENST00000322090.3:c.366C>T p.Asp122= p.D122= ENST00000322090 NM_001483.2 122 gaC/gaT 0 +GBF1 UCSF GRCh37 10 104136322 104136322 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 50 378 0 ENST00000369983.3:c.4050G>A p.Gly1350= p.G1350= ENST00000369983 NM_004193.2 1350 ggG/ggA 0 +GCLC UCSF GRCh37 6 53372382 53372382 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 47 136 0 ENST00000229416.6:c.980C>T p.Ser327Phe p.S327F ENST00000229416 NM_001197115.1 327 tCc/tTc 0 +GCN1L1 UCSF GRCh37 12 120585002 120585002 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 39 112 0 ENST00000300648.6:c.4801G>A p.Asp1601Asn p.D1601N ENST00000300648 NM_006836.1 1601 Gac/Aac 0 +GCNT2 UCSF GRCh37 6 10586526 10586526 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 34 307 0 ENST00000379597.3:c.926-35058G>A *309* ENST00000379597 0 +GDAP1 UCSF GRCh37 8 75276411 75276411 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 24 214 0 ENST00000220822.7:c.886G>A p.Val296Ile p.V296I ENST00000220822 NM_001040875.2 296 Gtc/Atc 0 +GDPD4 UCSF GRCh37 11 76928350 76928350 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 18 199 0 ENST00000315938.4:c.1535G>A p.Ser512Asn p.S512N ENST00000315938 NM_182833.1 512 aGt/aAt 0 +GDPD4 UCSF GRCh37 11 76990369 76990369 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 9 65 0 ENST00000315938.4:c.129C>T p.Ala43= p.A43= ENST00000315938 NM_182833.1 43 gcC/gcT 0 +GDPD5 UCSF GRCh37 11 75154180 75154180 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 12 75 0 ENST00000336898.3:c.948+1G>A p.X316_splice ENST00000336898 NM_030792.6 0 +GFOD1 UCSF GRCh37 6 13487026 13487026 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 218 164 395 0 ENST00000379287.3:c.97G>A p.Gly33Ser p.G33S ENST00000379287 NM_018988.3 33 Ggc/Agc 0 +GGA1 UCSF GRCh37 22 38026166 38026166 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 7 53 0 ENST00000343632.4:c.1320G>A p.Gln440= p.Q440= ENST00000343632 NM_013365.4 440 caG/caA 0 +GGA3 UCSF GRCh37 17 73237757 73237757 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 21 194 0 ENST00000245541.6:c.768G>A p.Glu256= p.E256= ENST00000245541 NM_138619.2 256 gaG/gaA 0 +GGT7 UCSF GRCh37 20 33460541 33460541 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 5 43 0 ENST00000336431.5:c.78C>T p.Ser26= p.S26= ENST00000336431 NM_178026.2 26 agC/agT 0 +GHITM UCSF GRCh37 10 85901270 85901270 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 29 199 0 ENST00000372134.3:c.14G>A p.Arg5Lys p.R5K ENST00000372134 NM_014394.2 5 aGg/aAg 0 +GIGYF1 UCSF GRCh37 7 100285184 100285184 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 49 165 0 ENST00000275732.5:c.317G>A p.Gly106Glu p.G106E ENST00000275732 NM_022574.4 106 gGg/gAg 0 +GIGYF1 UCSF GRCh37 7 100285626 100285626 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 21 200 0 ENST00000275732.5:c.143C>T p.Ala48Val p.A48V ENST00000275732 NM_022574.4 48 gCt/gTt 0 +GIGYF1 UCSF GRCh37 7 100280392 100280392 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 13 79 0 ENST00000275732.5:c.2421G>A p.Gly807= p.G807= ENST00000275732 NM_022574.4 807 ggG/ggA 0 +GIPC2 UCSF GRCh37 1 78511943 78511943 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 10 51 0 ENST00000370759.3:c.165C>T p.Gly55= p.G55= ENST00000370759 NM_017655.4 55 ggC/ggT 0 +GJA9 UCSF GRCh37 1 39340326 39340326 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 22 242 0 ENST00000357771.3:c.1445G>A p.Gly482Glu p.G482E ENST00000357771 NM_030772.4 482 gGg/gAg 0 +GJC2 UCSF GRCh37 1 228345498 228345498 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 7 85 0 ENST00000366714.2:c.39G>A p.Leu13= p.L13= ENST00000366714 NM_020435.3 13 ctG/ctA 0 +GLA UCSF GRCh37 X 100653432 100653432 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 12 53 0 ENST00000218516.3:c.925G>A p.Ala309Thr p.A309T ENST00000218516 NM_000169.2 309 Gct/Act 0 +GLI1 UCSF GRCh37 12 57865572 57865572 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 802 108 171 0 ENST00000228682.2:c.3049G>A p.Gly1017Ser p.G1017S ENST00000228682 NM_005269.2 1017 Ggc/Agc 0 +GNA11 UCSF GRCh37 19 3121050 3121050 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 17 130 0 ENST00000078429.4:c.953C>T p.Pro318Leu p.P318L ENST00000078429 NM_002067.2 318 cCc/cTc 0 +GNA12 UCSF GRCh37 7 2834768 2834768 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 74 236 0 ENST00000275364.3:c.319G>A p.Val107Ile p.V107I ENST00000275364 NM_007353.2 107 Gtt/Att 0 +GNB2L1 UCSF GRCh37 5 180666492 180666492 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 20 137 0 ENST00000512805.1:c.520G>A p.Val174Ile p.V174I ENST00000512805 NM_006098.4 174 Gtc/Atc 0 +GNPDA2 UCSF GRCh37 4 44709880 44709880 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 32 307 0 ENST00000295448.3:c.658G>A p.Val220Ile p.V220I ENST00000295448 NM_138335.2 220 Gtc/Atc 0 +GNPTAB UCSF GRCh37 12 102163923 102163923 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 27 254 0 ENST00000299314.7:c.1160C>T p.Ala387Val p.A387V ENST00000299314 NM_024312.4 387 gCt/gTt 0 +GNPTG UCSF GRCh37 16 1411918 1411918 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 25 222 0 ENST00000204679.4:c.279G>A p.Glu93= p.E93= ENST00000204679 NM_032520.4 93 gaG/gaA 0 +GOLGA1 UCSF GRCh37 9 127693594 127693594 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 6 48 0 ENST00000373555.4:c.226+1G>A p.X76_splice ENST00000373555 NM_002077.3 0 +GOLGA2 UCSF GRCh37 9 131028282 131028282 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 29 0 ENST00000421699.2:c.618C>T p.His206= p.H206= ENST00000421699 NM_004486.4 206 caC/caT 0 +GOLGB1 UCSF GRCh37 3 121412909 121412909 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 406 190 771 0 ENST00000393667.3:c.6461G>A p.Arg2154His p.R2154H ENST00000393667 NM_001256486.1 2154 cGc/cAc 0 +GOLGB1 UCSF GRCh37 3 121386937 121386937 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 8 77 0 ENST00000393667.3:c.9405C>T p.Asp3135= p.D3135= ENST00000393667 NM_001256486.1 3135 gaC/gaT 0 +GPIHBP1 UCSF GRCh37 8 144296979 144296979 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 10 97 0 ENST00000330824.2:c.273C>T p.Thr91= p.T91= ENST00000330824 NM_178172.3 91 acC/acT 0 +GPR124 UCSF GRCh37 8 37691227 37691227 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 28 189 0 ENST00000412232.2:c.1318G>A p.Ala440Thr p.A440T ENST00000412232 NM_032777.9 440 Gcg/Acg 0 +GPR126 UCSF GRCh37 6 142741137 142741137 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 18 154 0 ENST00000367609.3:c.3215G>A p.Ser1072Asn p.S1072N ENST00000367609 NM_198569.2 1072 aGc/aAc 0 +GPR132 UCSF GRCh37 14 105518041 105518041 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 22 199 0 ENST00000329797.3:c.433G>A p.Val145Met p.V145M ENST00000329797 NM_013345.3 145 Gtg/Atg 0 +GPR143 UCSF GRCh37 X 9714171 9714171 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 52 0 ENST00000467482.1:c.571G>A p.Ala191Thr p.A191T ENST00000467482 191 Gcc/Acc 0 +GPR156 UCSF GRCh37 3 119905531 119905531 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 37 276 0 ENST00000464295.1:c.574C>T p.Leu192Phe p.L192F ENST00000464295 192 Ctc/Ttc 0 +GPR160 UCSF GRCh37 3 169801841 169801841 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 224 29 368 0 ENST00000355897.5:c.81G>A p.Leu27= p.L27= ENST00000355897 NM_014373.2 27 ctG/ctA 0 +GPR179 UCSF GRCh37 17 36482967 36482967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 468 90 649 0 ENST00000342292.4:c.6485C>T p.Pro2162Leu p.P2162L ENST00000342292 NM_001004334.2 2162 cCt/cTt 0 +GPR37L1 UCSF GRCh37 1 202097390 202097390 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 212 47 249 0 ENST00000367282.5:c.1152C>T p.Tyr384= p.Y384= ENST00000367282 NM_004767.3 384 taC/taT 0 +GPR50 UCSF GRCh37 X 150349701 150349701 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 49 231 0 ENST00000218316.3:c.1646C>T p.Ala549Val p.A549V ENST00000218316 NM_004224.3 549 gCc/gTc 0 +GPR77 UCSF GRCh37 19 47844575 47844575 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 27 226 0 ENST00000595464.1:c.519C>T p.Arg173= p.R173= ENST00000595464 NM_001271749.1 173 cgC/cgT 0 +GPR77 UCSF GRCh37 19 47844816 47844816 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 26 164 0 ENST00000595464.1:c.760C>T p.Leu254= p.L254= ENST00000595464 NM_001271749.1 254 Ctg/Ttg 0 +GPR98 UCSF GRCh37 5 89979842 89979842 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 27 228 0 ENST00000405460.2:c.6104C>T p.Thr2035Ile p.T2035I ENST00000405460 NM_032119.3 2035 aCt/aTt 0 +GPR98 UCSF GRCh37 5 90459629 90459629 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 23 212 0 ENST00000405460.2:c.18833C>T p.Ser6278Phe p.S6278F ENST00000405460 NM_032119.3 6278 tCt/tTt 0 +GPR98 UCSF GRCh37 5 89930943 89930943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 13 128 0 ENST00000405460.2:c.1852G>A p.Glu618Lys p.E618K ENST00000405460 NM_032119.3 618 Gag/Aag 0 +GPR98 UCSF GRCh37 5 89939622 89939622 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 32 111 0 ENST00000405460.2:c.2556G>A p.Leu852= p.L852= ENST00000405460 NM_032119.3 852 ttG/ttA 0 +GPRIN3 UCSF GRCh37 4 90168988 90168988 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 14 142 0 ENST00000609438.1:c.2274G>A p.Gln758= p.Q758= ENST00000609438 NM_198281.2 758 caG/caA 0 +GRAMD1B UCSF GRCh37 11 123479372 123479372 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 233 42 361 0 ENST00000529750.1:c.1090G>A p.Val364Ile p.V364I ENST00000529750 NM_020716.1 364 Gtc/Atc 0 +GRAMD1B UCSF GRCh37 11 123448180 123448180 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 34 271 0 ENST00000529750.1:c.129G>A p.Glu43= p.E43= ENST00000529750 NM_020716.1 43 gaG/gaA 0 +GRHPR UCSF GRCh37 9 37436728 37436728 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 7 94 0 ENST00000318158.6:c.936C>T p.Asn312= p.N312= ENST00000318158 NM_012203.1 312 aaC/aaT 0 +GRID1 UCSF GRCh37 10 87362214 87362214 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 15 99 0 ENST00000327946.7:c.2846G>A p.Ser949Asn p.S949N ENST00000327946 NM_017551.2 949 aGc/aAc 0 +GRIN2A UCSF GRCh37 16 9857613 9857613 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 24 241 0 ENST00000330684.3:c.3788G>A p.Gly1263Glu p.G1263E ENST00000330684 NM_001134407.1 1263 gGg/gAg 0 +GRIPAP1 UCSF GRCh37 X 48832511 48832511 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 9 23 47 0 ENST00000376441.1:c.2197G>A p.Glu733Lys p.E733K ENST00000376441 NM_020137.3 733 Gaa/Aaa 0 +GRK4 UCSF GRCh37 4 3029687 3029687 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 20 120 0 ENST00000398052.4:c.1019G>A p.Gly340Glu p.G340E ENST00000398052 NM_182982.2 340 gGa/gAa 0 +GRK4 UCSF GRCh37 4 3021409 3021409 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 32 227 0 ENST00000398052.4:c.783C>T p.Cys261= p.C261= ENST00000398052 NM_182982.2 261 tgC/tgT 0 +GRM2 UCSF GRCh37 3 51743012 51743012 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 6 63 0 ENST00000395052.3:c.13C>T p.Leu5Phe p.L5F ENST00000395052 NM_000839.3 5 Ctt/Ttt 0 +GRM7 UCSF GRCh37 3 6903548 6903548 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 64 203 0 ENST00000357716.4:c.473G>A p.Gly158Glu p.G158E ENST00000357716 NM_000844.3 158 gGg/gAg 0 +GRM7 UCSF GRCh37 3 7620195 7620195 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 211 25 280 0 ENST00000357716.4:c.1602G>A p.Lys534= p.K534= ENST00000357716 NM_000844.3 534 aaG/aaA 0 +GRM8 UCSF GRCh37 7 126086146 126086146 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 45 165 0 ENST00000339582.2:c.2677+34G>A *893* ENST00000339582 0 +GRSF1 UCSF GRCh37 4 71698972 71698972 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 16 124 0 ENST00000254799.6:c.533G>A p.Gly178Asp p.G178D ENST00000254799 NM_002092.3 178 gGt/gAt 0 +GSDMA UCSF GRCh37 17 38132196 38132196 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 27 251 0 ENST00000301659.4:c.1041G>A p.Gln347= p.Q347= ENST00000301659 NM_178171.4 347 caG/caA 0 +GSDMB UCSF GRCh37 17 38062477 38062477 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 277 35 374 0 ENST00000418519.1:c.775G>A p.Glu259Lys p.E259K ENST00000418519 NM_001165958.1 259 Gag/Aag 0 +GSG2 UCSF GRCh37 17 3628465 3628465 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 490 68 672 0 ENST00000325418.4:c.1236C>T p.Leu412= p.L412= ENST00000325418 NM_031965.2 412 ctC/ctT 0 +GSPT1 UCSF GRCh37 16 11981543 11981543 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 23 132 0 ENST00000434724.2:c.841G>A p.Gly281Ser p.G281S ENST00000434724 NM_002094.3 281 Ggt/Agt 0 +GTF3C1 UCSF GRCh37 16 27500465 27500465 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 28 172 0 ENST00000356183.4:c.3328C>T p.Pro1110Ser p.P1110S ENST00000356183 NM_001520.3 1110 Cct/Tct 0 +GUCY1A2 UCSF GRCh37 11 106680975 106680975 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 234 41 325 0 ENST00000282249.2:c.1436C>T p.Thr479Ile p.T479I ENST00000282249 NM_001256424.1 479 aCt/aTt 0 +GUCY2D UCSF GRCh37 17 7906839 7906839 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 10 22 0 ENST00000254854.4:c.474G>A p.Glu158= p.E158= ENST00000254854 NM_000180.3 158 gaG/gaA 0 +GUSB UCSF GRCh37 7 65441159 65441159 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 21 158 0 ENST00000304895.4:c.755G>A p.Gly252Asp p.G252D ENST00000304895 NM_000181.3 252 gGc/gAc 0 +H6PD UCSF GRCh37 1 9324292 9324292 + synonymous_variant Silent SNP G G A snp132_rs112516051 P24_Rec2 Untested WXS Illumina HiSeq 107 21 123 0 ENST00000377403.2:c.1740G>A p.Arg580= p.R580= ENST00000377403 NM_004285.3 580 cgG/cgA 0 +HACL1 UCSF GRCh37 3 15631079 15631079 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 5 70 0 ENST00000321169.5:c.349G>A p.Glu117Lys p.E117K ENST00000321169 NM_012260.2 117 Gaa/Aaa 0 +HCAR1 UCSF GRCh37 12 123214554 123214554 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 13 125 0 ENST00000432564.1:c.333G>A p.Ala111= p.A111= ENST00000432564 NM_032554.3 111 gcG/gcA 0 +HCN2 UCSF GRCh37 19 613904 613904 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 8 51 0 ENST00000251287.2:c.1878C>T p.Thr626= p.T626= ENST00000251287 NM_001194.3 626 acC/acT 0 +HCN3 UCSF GRCh37 1 155257939 155257939 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 18 143 0 ENST00000368358.3:c.2010C>T p.Arg670= p.R670= ENST00000368358 NM_020897.2 670 cgC/cgT 0 +HCST UCSF GRCh37 19 36394294 36394294 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 363 42 484 0 ENST00000246551.4:c.85C>T p.Pro29Ser p.P29S ENST00000246551 29 Cct/Tct 0 +HDAC1 UCSF GRCh37 1 32782331 32782331 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 136 24 159 0 ENST00000373548.3:c.228G>A p.Leu76= p.L76= ENST00000373548 NM_004964.2 76 ttG/ttA 0 +HDDC3 UCSF GRCh37 15 91475314 91475314 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 103 0 ENST00000330334.3:c.139G>A p.Ala47Thr p.A47T ENST00000330334 NM_198527.2 47 Gcg/Acg 0 +HEATR4 UCSF GRCh37 14 73989011 73989011 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 9 98 0 ENST00000553558.1:c.846G>A p.Lys282= p.K282= ENST00000553558 NM_001220484.1 282 aaG/aaA 0 +HEATR5B UCSF GRCh37 2 37215869 37215869 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 5 50 0 ENST00000233099.5:c.5831C>T p.Ala1944Val p.A1944V ENST00000233099 NM_019024.1 1944 gCc/gTc 0 +HECTD1 UCSF GRCh37 14 31576053 31576053 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 26 235 0 ENST00000399332.1:c.7025G>A p.Gly2342Glu p.G2342E ENST00000399332 NM_015382.2 2342 gGa/gAa 0 +HECTD1 UCSF GRCh37 14 31613428 31613428 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 25 263 0 ENST00000399332.1:c.2667G>A p.Met889Ile p.M889I ENST00000399332 NM_015382.2 889 atG/atA 0 +HECTD1 UCSF GRCh37 14 31576304 31576304 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 11 161 0 ENST00000399332.1:c.6774C>T p.Asp2258= p.D2258= ENST00000399332 NM_015382.2 2258 gaC/gaT 0 +HECW1 UCSF GRCh37 7 43483838 43483838 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 16 120 0 ENST00000395891.2:c.1067G>A p.Ser356Asn p.S356N ENST00000395891 NM_015052.3 356 aGt/aAt 0 +HELT UCSF GRCh37 4 185941579 185941579 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 10 135 0 ENST00000338875.4:c.637C>T p.Leu213= p.L213= ENST00000338875 NM_001029887.1 213 Ctg/Ttg 0 +HELZ UCSF GRCh37 17 65104735 65104735 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 20 141 0 ENST00000358691.5:c.4597C>T p.Pro1533Ser p.P1533S ENST00000358691 NM_014877.3 1533 Cca/Tca 0 +HENMT1 UCSF GRCh37 1 109192907 109192910 + frameshift_variant Frame_Shift_Del DEL TTCC TTCC - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 0 ENST00000370032.5:c.679_682del p.Gly227SerfsTer55 p.G227Sfs*55 ENST00000370032 NM_144584.2 227 GGAAtc/tc 0 +HEPACAM UCSF GRCh37 11 124794649 124794649 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 36 240 0 ENST00000298251.4:c.402G>A p.Glu134= p.E134= ENST00000298251 NM_152722.4 134 gaG/gaA 0 +HEPH UCSF GRCh37 X 65414964 65414964 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 3 22 0 ENST00000519389.1:c.1556G>A p.Gly519Asp p.G519D ENST00000519389 519 gGt/gAt 0 +HEPHL1 UCSF GRCh37 11 93797501 93797501 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 11 91 0 ENST00000315765.9:c.633C>T p.Ile211= p.I211= ENST00000315765 NM_001098672.1 211 atC/atT 0 +HERC1 UCSF GRCh37 15 63922732 63922732 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 392 55 511 0 ENST00000443617.2:c.12899C>T p.Ala4300Val p.A4300V ENST00000443617 NM_003922.3 4300 gCt/gTt 0 +HERC2 UCSF GRCh37 15 28436142 28436142 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 75 0 ENST00000261609.7:c.8618C>T p.Thr2873Ile p.T2873I ENST00000261609 NM_004667.5 2873 aCc/aTc 0 +HERC2 UCSF GRCh37 15 28386941 28386941 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 234 32 333 0 ENST00000261609.7:c.11752C>T p.Leu3918= p.L3918= ENST00000261609 NM_004667.5 3918 Ctg/Ttg 0 +HERC5 UCSF GRCh37 4 89389506 89389506 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 7 76 0 ENST00000264350.3:c.1067C>T p.Thr356Ile p.T356I ENST00000264350 NM_016323.3 356 aCc/aTc 0 +HFE2 UCSF GRCh37 1 145416933 145416933 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 311 55 453 0 ENST00000336751.5:c.1278G>A p.Gln426= p.Q426= ENST00000336751 NM_213653.3 426 caG/caA 0 +HGFAC UCSF GRCh37 4 3449664 3449664 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 4 60 0 ENST00000382774.3:c.1538G>A p.Arg513His p.R513H ENST00000382774 NM_001528.2 513 cGc/cAc 0 +HIC2 UCSF GRCh37 22 21799854 21799854 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 8 73 0 ENST00000443632.2:c.670G>A p.Glu224Lys p.E224K ENST00000443632 224 Gag/Aag 0 +HIP1 UCSF GRCh37 7 75176264 75176264 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 63 0 ENST00000336926.6:c.2532C>T p.Leu844= p.L844= ENST00000336926 NM_005338.6 844 ctC/ctT 0 +HIST1H2AK UCSF GRCh37 6 27805862 27805862 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 12 104 0 ENST00000330180.2:c.256C>T p.Leu86= p.L86= ENST00000330180 NM_003510.2 86 Ctg/Ttg 0 +HIST1H2BK UCSF GRCh37 6 27114231 27114231 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 11 98 0 ENST00000396891.4:c.347C>T p.Thr116Ile p.T116I ENST00000396891 NM_080593.2 116 aCc/aTc 0 +HJURP UCSF GRCh37 2 234750741 234750741 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 28 294 0 ENST00000411486.2:c.685C>T p.Pro229Ser p.P229S ENST00000411486 NM_018410.3 229 Cct/Tct 0 +HMCN1 UCSF GRCh37 1 186039746 186039746 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 25 254 0 ENST00000271588.4:c.7996C>T p.Pro2666Ser p.P2666S ENST00000271588 NM_031935.2 2666 Cca/Tca 0 +HMCN1 UCSF GRCh37 1 186107095 186107095 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 4 37 0 ENST00000271588.4:c.13915C>T p.Pro4639Ser p.P4639S ENST00000271588 NM_031935.2 4639 Cct/Tct 0 +HMMR UCSF GRCh37 5 162896656 162896656 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 13 89 0 ENST00000393915.4:c.283C>T p.Leu95Phe p.L95F ENST00000393915 NM_001142556.1 95 Ctt/Ttt 0 +HNRNPU UCSF GRCh37 1 245021421 245021421 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 222 31 271 0 ENST00000283179.9:c.1386G>A p.Lys462= p.K462= ENST00000283179 462 aaG/aaA 0 +HNRNPUL1 UCSF GRCh37 19 41774156 41774156 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 58 0 ENST00000392006.3:c.324C>T p.Asn108= p.N108= ENST00000392006 NM_007040.3 108 aaC/aaT 0 +HOGA1 UCSF GRCh37 10 99358621 99358621 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 9 116 0 ENST00000370646.4:c.301C>T p.Pro101Ser p.P101S ENST00000370646 NM_138413.3 101 Ccc/Tcc 0 +HOXA11 UCSF GRCh37 7 27224318 27224318 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 28 120 0 ENST00000006015.3:c.446G>A p.Gly149Asp p.G149D ENST00000006015 NM_005523.5 149 gGc/gAc 0 +HOXB1 UCSF GRCh37 17 46608212 46608212 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 8 91 0 ENST00000239174.6:c.55C>T p.Pro19Ser p.P19S ENST00000239174 NM_002144.3 19 Ccc/Tcc 0 +HOXB2 UCSF GRCh37 17 46622042 46622042 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 8 42 0 ENST00000330070.4:c.232C>T p.Leu78= p.L78= ENST00000330070 NM_002145.3 78 Ctg/Ttg 0 +HOXB8 UCSF GRCh37 17 46691826 46691826 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 24 220 0 ENST00000239144.4:c.241G>A p.Asp81Asn p.D81N ENST00000239144 NM_024016.3 81 Gac/Aac 0 +HOXC12 UCSF GRCh37 12 54350237 54350237 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 11 62 0 ENST00000243103.3:c.736G>A p.Glu246Lys p.E246K ENST00000243103 NM_173860.1 246 Gaa/Aaa 0 +HOXC8 UCSF GRCh37 12 54403386 54403389 + frameshift_variant Frame_Shift_Del DEL GAGC GAGC AAG NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 0 ENST00000040584.4:c.318_321delinsAAG p.Ser107ArgfsTer23 p.S107Rfs*23 ENST00000040584 NM_022658.3 106 gcGAGC/gcAAG 0 +HOXD9 UCSF GRCh37 2 176987832 176987832 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 7 86 0 ENST00000249499.6:c.336C>T p.Pro112= p.P112= ENST00000249499 NM_014213.3 112 ccC/ccT 0 +HPCA UCSF GRCh37 1 33359382 33359382 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 161 31 226 0 ENST00000373467.3:c.501G>A p.Glu167= p.E167= ENST00000373467 NM_002143.2 167 gaG/gaA 0 +HPS4 UCSF GRCh37 22 26864578 26864578 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 18 115 0 ENST00000398145.2:c.608C>T p.Thr203Ile p.T203I ENST00000398145 NM_022081.5 203 aCc/aTc 0 +HPS4 UCSF GRCh37 22 26860252 26860252 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 27 149 0 ENST00000398145.2:c.1344C>T p.Gly448= p.G448= ENST00000398145 NM_022081.5 448 ggC/ggT 0 +HR UCSF GRCh37 8 21978318 21978318 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 22 158 0 ENST00000381418.4:c.2521C>T p.Pro841Ser p.P841S ENST00000381418 NM_005144.4 841 Ccc/Tcc 0 +HRC UCSF GRCh37 19 49656929 49656929 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 332 57 505 0 ENST00000252825.4:c.1566G>A p.Glu522= p.E522= ENST00000252825 NM_002152.2 522 gaG/gaA 0 +HRH2 UCSF GRCh37 5 175110611 175110611 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 423 74 627 0 ENST00000377291.2:c.375G>A p.Arg125= p.R125= ENST00000377291 NM_001131055.1 125 cgG/cgA 0 +HRNR UCSF GRCh37 1 152191458 152191458 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 13 131 0 ENST00000368801.2:c.2647C>T p.His883Tyr p.H883Y ENST00000368801 NM_001009931.2 883 Cat/Tat 0 +HSD3B1 UCSF GRCh37 1 120056648 120056648 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 9 113 0 ENST00000369413.3:c.502G>A p.Ala168Thr p.A168T ENST00000369413 168 Gcg/Acg 0 +HSD3B2 UCSF GRCh37 1 119964551 119964551 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 7 73 0 ENST00000543831.1:c.427G>A p.Glu143Lys p.E143K ENST00000543831 NM_001166120.1 143 Gaa/Aaa 0 +HSPA9 UCSF GRCh37 5 137895578 137895578 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 12 103 0 ENST00000297185.3:c.1385C>T p.Thr462Ile p.T462I ENST00000297185 NM_004134.6 462 aCc/aTc 0 +HSPB3 UCSF GRCh37 5 53751797 53751797 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 22 219 0 ENST00000302005.1:c.178G>A p.Ala60Thr p.A60T ENST00000302005 NM_006308.2 60 Gca/Aca 0 +HSPB9 UCSF GRCh37 17 40275126 40275126 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 19 141 0 ENST00000355067.3:c.258C>T p.Asp86= p.D86= ENST00000355067 NM_033194.2 86 gaC/gaT 0 +HSPB9 UCSF GRCh37 17 40275195 40275195 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 248 45 311 0 ENST00000355067.3:c.327C>T p.Asn109= p.N109= ENST00000355067 NM_033194.2 109 aaC/aaT 0 +HTRA3 UCSF GRCh37 4 8304200 8304200 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 21 223 0 ENST00000307358.2:c.1062G>A p.Lys354= p.K354= ENST00000307358 NM_053044.3 354 aaG/aaA 0 +HYAL2 UCSF GRCh37 3 50357515 50357515 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 70 169 0 ENST00000447092.1:c.406G>A p.Asp136Asn p.D136N ENST00000447092 136 Gac/Aac 0 +HYDIN UCSF GRCh37 16 70841568 70841568 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 35 138 0 ENST00000393567.2:c.15281C>T p.Thr5094Ile p.T5094I ENST00000393567 NM_001270974.1 5094 aCc/aTc 0 +HYI UCSF GRCh37 1 43917481 43917481 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 16 143 0 ENST00000372425.4:c.543C>T p.Leu181= p.L181= ENST00000372425 181 ctC/ctT 0 +IARS UCSF GRCh37 9 95009661 95009661 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 38 221 0 ENST00000375643.3:c.2789C>T p.Thr930Ile p.T930I ENST00000375643 NM_013417.3 930 aCt/aTt 0 +IBTK UCSF GRCh37 6 82936964 82936964 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 33 332 0 ENST00000306270.7:c.599C>T p.Thr200Ile p.T200I ENST00000306270 NM_015525.2 200 aCc/aTc 0 +ICA1L UCSF GRCh37 2 203644301 203644301 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 12 155 0 ENST00000392237.2:c.1404C>T p.Asn468= p.N468= ENST00000392237 NM_138468.4 468 aaC/aaT 0 +ID2 UCSF GRCh37 2 8822431 8822431 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 28 234 0 ENST00000234091.4:c.136C>T p.Leu46Phe p.L46F ENST00000234091 46 Ctc/Ttc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 9 8 28 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IER5 UCSF GRCh37 1 181058475 181058475 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 13 35 0 ENST00000367577.4:c.437G>A p.Gly146Glu p.G146E ENST00000367577 NM_016545.4 146 gGg/gAg 0 +IER5L UCSF GRCh37 9 131940255 131940255 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 14 131 0 ENST00000372491.2:c.77G>A p.Gly26Asp p.G26D ENST00000372491 NM_203434.2 26 gGc/gAc 0 +IFFO1 UCSF GRCh37 12 6660128 6660128 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 11 61 0 ENST00000356896.4:c.813C>T p.Asp271= p.D271= ENST00000356896 NM_001039670.2 271 gaC/gaT 0 +IFIT2 UCSF GRCh37 10 91066329 91066329 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 36 338 0 ENST00000371826.3:c.616C>T p.Pro206Ser p.P206S ENST00000371826 NM_001547.4 206 Cct/Tct 0 +IFITM2 UCSF GRCh37 11 308246 308246 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 8 40 0 ENST00000399817.4:c.54C>T p.Asn18= p.N18= ENST00000399817 NM_006435.2 18 aaC/aaT 0 +IFITM3 UCSF GRCh37 11 319894 319894 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 18 203 0 ENST00000399808.4:c.346C>T p.Leu116Phe p.L116F ENST00000399808 NM_021034.2 116 Ctc/Ttc 0 +IFNA8 UCSF GRCh37 9 21409203 21409203 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 25 292 0 ENST00000380205.1:c.28G>A p.Ala10Thr p.A10T ENST00000380205 NM_002170.3 10 Gcc/Acc 0 +IFNAR2 UCSF GRCh37 21 34635415 34635415 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 58 197 0 ENST00000342136.4:c.1158G>A p.Gln386= p.Q386= ENST00000342136 386 caG/caA 0 +IFT80 UCSF GRCh37 3 159976317 159976317 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 18 139 0 ENST00000326448.7:c.2330C>T p.Pro777Leu p.P777L ENST00000326448 NM_020800.2 777 cCc/cTc 0 +IGF1R UCSF GRCh37 15 99465622 99465622 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 32 235 0 ENST00000268035.6:c.2447G>A p.Ser816Asn p.S816N ENST00000268035 NM_000875.3 816 aGc/aAc 0 +IGF2R UCSF GRCh37 6 160485892 160485892 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 39 257 0 ENST00000356956.1:c.4074G>A p.Gln1358= p.Q1358= ENST00000356956 NM_000876.2 1358 caG/caA 0 +IGFBP1 UCSF GRCh37 7 45928394 45928394 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 5 45 0 ENST00000275525.3:c.143G>A p.Cys48Tyr p.C48Y ENST00000275525 NM_000596.2 48 tGc/tAc 0 +IGLON5 UCSF GRCh37 19 51830417 51830417 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 15 147 0 ENST00000270642.8:c.730C>T p.Pro244Ser p.P244S ENST00000270642 NM_001101372.1 244 Ccc/Tcc 0 +IGSF3 UCSF GRCh37 1 117122089 117122089 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 14 145 0 ENST00000369483.1:c.3319C>T p.Pro1107Ser p.P1107S ENST00000369483 NM_001542.3 1107 Ccc/Tcc 0 +IKBKB UCSF GRCh37 8 42129684 42129684 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 145 22 140 0 ENST00000520810.1:c.66G>A p.Gly22= p.G22= ENST00000520810 NM_001556.2 22 ggG/ggA 0 +IL17RB UCSF GRCh37 3 53890927 53890927 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 24 202 0 ENST00000288167.3:c.586G>A p.Val196Met p.V196M ENST00000288167 NM_018725.3 196 Gtg/Atg 0 +IL17RE UCSF GRCh37 3 9956252 9956252 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 191 29 214 0 ENST00000295980.3:c.1317G>A p.Gln439= p.Q439= ENST00000295980 NM_153483.2 439 caG/caA 0 +IL18 UCSF GRCh37 11 112025712 112025712 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.00273,snp132_rs61734549 P24_Rec2 Untested WXS Illumina HiSeq 90 38 171 0 ENST00000280357.7:c.65C>T p.Thr22Met p.T22M ENST00000280357 NM_001562.3 22 aCg/aTg 0 +IL1RAP UCSF GRCh37 3 190326923 190326923 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 11 139 0 ENST00000317757.3:c.490G>A p.Asp164Asn p.D164N ENST00000317757 NM_001167931.1 164 Gat/Aat 0 +IL1RAP UCSF GRCh37 3 190345117 190345117 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 11 138 0 ENST00000317757.3:c.781G>A p.Glu261Lys p.E261K ENST00000317757 NM_001167931.1 261 Gag/Aag 0 +IL20RB UCSF GRCh37 3 136710829 136710829 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 10 94 0 ENST00000329582.4:c.581C>T p.Thr194Ile p.T194I ENST00000329582 NM_144717.3 194 aCc/aTc 0 +IL21 UCSF GRCh37 4 123542065 123542065 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 80 290 0 ENST00000264497.3:c.102C>T p.Arg34= p.R34= ENST00000264497 NM_021803.3 34 cgC/cgT 0 +IL4R UCSF GRCh37 16 27353453 27353453 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 55 168 0 ENST00000395762.2:c.82G>A p.Val28Ile p.V28I ENST00000395762 NM_000418.3 28 Gtc/Atc 0 +IL4R UCSF GRCh37 16 27351507 27351507 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 30 71 0 ENST00000395762.2:c.-18G>A p.X6_splice ENST00000395762 NM_000418.3 0 +IMMP2L UCSF GRCh37 7 110303686 110303686 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 25 238 0 ENST00000405709.2:c.500G>A p.Arg167His p.R167H ENST00000405709 NM_032549.3 167 cGc/cAc 0 +INADL UCSF GRCh37 1 62293175 62293175 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 13 48 0 ENST00000371158.2:c.1900G>A p.Val634Ile p.V634I ENST00000371158 NM_176877.2 634 Gtt/Att 0 +INO80D UCSF GRCh37 2 206874416 206874416 + stop_gained Nonsense_Mutation SNP T T A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 12 65 0 ENST00000403263.1:c.1645A>T p.Lys549Ter p.K549* ENST00000403263 NM_017759.4 549 Aag/Tag 0 +INPP1 UCSF GRCh37 2 191224847 191224847 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 11 34 0 ENST00000392329.2:c.19G>A p.Glu7Lys p.E7K ENST00000392329 NM_001128928.1 7 Gag/Aag 0 +INPP5J UCSF GRCh37 22 31529913 31529913 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 19 133 0 ENST00000404390.3:c.1425C>T p.Ser475= p.S475= ENST00000404390 NM_001002837.1 475 tcC/tcT 0 +INTS1 UCSF GRCh37 7 1517564 1517564 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 10 5 24 0 ENST00000404767.3:c.4639G>A p.Gly1547Arg p.G1547R ENST00000404767 NM_001080453.2 1547 Ggg/Agg 0 +INTS12 UCSF GRCh37 4 106613132 106613132 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 12 121 0 ENST00000451321.2:c.657+1G>A p.X219_splice ENST00000451321 NM_001142471.1 0 +INTS3 UCSF GRCh37 1 153737438 153737438 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 272 43 324 0 ENST00000318967.2:c.1989G>A p.Gln663= p.Q663= ENST00000318967 NM_023015.3 663 caG/caA 0 +INTS6 UCSF GRCh37 13 51952403 51952403 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 6 65 0 ENST00000311234.4:c.1574C>T p.Thr525Ile p.T525I ENST00000311234 NM_012141.2 525 aCt/aTt 0 +INTS9 UCSF GRCh37 8 28635391 28635391 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 13 132 0 ENST00000521022.1:c.1350C>T p.Thr450= p.T450= ENST00000521022 NM_018250.3 450 acC/acT 0 +IPO13 UCSF GRCh37 1 44415262 44415262 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 217 25 291 0 ENST00000372343.3:c.258C>T p.Ile86= p.I86= ENST00000372343 NM_014652.3 86 atC/atT 0 +IQCG UCSF GRCh37 3 197665484 197665484 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 24 343 0 ENST00000265239.6:c.450C>T p.Val150= p.V150= ENST00000265239 NM_032263.3 150 gtC/gtT 0 +IQCH UCSF GRCh37 15 67713652 67713652 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 10 101 0 ENST00000335894.4:c.2242C>T p.Pro748Ser p.P748S ENST00000335894 NM_001031715.2 748 Cct/Tct 0 +IQGAP1 UCSF GRCh37 15 90997763 90997763 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 11 129 0 ENST00000268182.5:c.1591G>A p.Val531Met p.V531M ENST00000268182 NM_003870.3 531 Gtg/Atg 0 +IQGAP1 UCSF GRCh37 15 91035809 91035809 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 8 106 0 ENST00000268182.5:c.4494G>A p.Arg1498= p.R1498= ENST00000268182 NM_003870.3 1498 agG/agA 0 +IQGAP3 UCSF GRCh37 1 156524122 156524122 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 13 91 0 ENST00000361170.2:c.1353C>T p.Asn451= p.N451= ENST00000361170 NM_178229.4 451 aaC/aaT 0 +IQSEC2 UCSF GRCh37 X 53350028 53350028 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 57 170 0 ENST00000396435.3:c.294C>T p.His98= p.H98= ENST00000396435 NM_001111125.2 98 caC/caT 0 +IRAK2 UCSF GRCh37 3 10280464 10280464 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 18 171 0 ENST00000256458.4:c.1506G>A p.Arg502= p.R502= ENST00000256458 NM_001570.3 502 cgG/cgA 0 +IRF5 UCSF GRCh37 7 128587398 128587398 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 16 79 0 ENST00000357234.5:c.596C>T p.Thr199Ile p.T199I ENST00000357234 199 aCt/aTt 0 +IRS2 UCSF GRCh37 13 110436746 110436746 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 32 230 0 ENST00000375856.3:c.1655G>A p.Cys552Tyr p.C552Y ENST00000375856 NM_003749.2 552 tGt/tAt 0 +ISLR2 UCSF GRCh37 15 74425298 74425298 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 16 123 0 ENST00000361742.3:c.203G>A p.Arg68His p.R68H ENST00000361742 NM_001130136.1 68 cGc/cAc 0 +ISM1 UCSF GRCh37 20 13251391 13251391 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 175 26 249 0 ENST00000262487.4:c.378+1G>A p.X126_splice ENST00000262487 NM_080826.1 0 +ITFG1 UCSF GRCh37 16 47494809 47494809 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 144 25 172 0 ENST00000320640.6:c.148C>T p.Leu50Phe p.L50F ENST00000320640 NM_030790.3 50 Ctt/Ttt 0 +ITGA11 UCSF GRCh37 15 68612657 68612657 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 13 104 0 ENST00000315757.7:c.2482G>A p.Val828Ile p.V828I ENST00000315757 NM_001004439.1 828 Gtc/Atc 0 +ITGAL UCSF GRCh37 16 30492887 30492887 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 25 206 0 ENST00000356798.6:c.704G>A p.Gly235Asp p.G235D ENST00000356798 NM_002209.2 235 gGt/gAt 0 +ITGAL UCSF GRCh37 16 30532967 30532967 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 5 33 0 ENST00000356798.6:c.3494G>A p.Ser1165Asn p.S1165N ENST00000356798 NM_002209.2 1165 aGt/aAt 0 +ITGAX UCSF GRCh37 16 31382817 31382817 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 34 351 1 ENST00000268296.4:c.2004C>T p.Ser668= p.S668= ENST00000268296 NM_000887.3 668 agC/agT 0 +ITIH3 UCSF GRCh37 3 52836799 52836799 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 16 99 0 ENST00000449956.2:c.1686C>T p.Thr562= p.T562= ENST00000449956 NM_002217.3 562 acC/acT 0 +ITPKB UCSF GRCh37 1 226924158 226924158 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 183 27 191 0 ENST00000429204.1:c.1002G>A p.Glu334= p.E334= ENST00000429204 NM_002221.3 334 gaG/gaA 0 +ITPR1 UCSF GRCh37 3 4699885 4699885 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 43 347 1 ENST00000302640.8:c.1029G>A p.Val343= p.V343= ENST00000302640 NM_001168272.1 343 gtG/gtA 0 +ITPR2 UCSF GRCh37 12 26748513 26748513 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 5 95 0 ENST00000381340.3:c.4265C>T p.Ala1422Val p.A1422V ENST00000381340 NM_002223.2 1422 gCt/gTt 0 +ITPRIPL2 UCSF GRCh37 16 19126795 19126795 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 15 131 0 ENST00000381440.3:c.1012C>T p.Pro338Ser p.P338S ENST00000381440 NM_001034841.3 338 Cct/Tct 0 +ITSN1 UCSF GRCh37 21 35140087 35140087 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 17 192 0 ENST00000381318.3:c.997C>T p.Pro333Ser p.P333S ENST00000381318 NM_003024.2 333 Cca/Tca 0 +ITSN2 UCSF GRCh37 2 24432863 24432863 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 7 89 0 ENST00000355123.4:c.4297C>T p.Arg1433Trp p.R1433W ENST00000355123 NM_006277.2 1433 Cgg/Tgg 0 +ITSN2 UCSF GRCh37 2 24433813 24433813 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 42 0 ENST00000355123.4:c.4093C>T p.Leu1365= p.L1365= ENST00000355123 NM_006277.2 1365 Ctg/Ttg 0 +IWS1 UCSF GRCh37 2 128250901 128250901 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 12 102 0 ENST00000295321.4:c.1885C>T p.Pro629Ser p.P629S ENST00000295321 NM_017969.2 629 Cct/Tct 0 +JAG2 UCSF GRCh37 14 105609197 105609197 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 34 212 0 ENST00000331782.3:c.3552C>T p.Gly1184= p.G1184= ENST00000331782 NM_002226.4 1184 ggC/ggT 0 +JAKMIP1 UCSF GRCh37 4 6107536 6107536 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 33 244 0 ENST00000409021.3:c.288G>A p.Glu96= p.E96= ENST00000409021 NM_001099433.1 96 gaG/gaA 0 +JAM2 UCSF GRCh37 21 27078290 27078290 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 49 176 0 ENST00000400532.1:c.698-1G>A p.X233_splice ENST00000400532 NM_001270408.1 0 +JMJD7-PLA2G4B UCSF GRCh37 15 42139646 42139646 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 258 47 390 0 ENST00000382448.4:c.2752C>T p.Pro918Ser p.P918S ENST00000382448 918 Ccc/Tcc 0 +KALRN UCSF GRCh37 3 124303687 124303687 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 6 45 0 ENST00000291478.5:c.19G>A p.Ala7Thr p.A7T ENST00000291478 NM_007064.3 7 Gct/Act 0 +KATNAL1 UCSF GRCh37 13 30804647 30804647 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 17 175 0 ENST00000380615.3:c.970G>A p.Ala324Thr p.A324T ENST00000380615 NM_032116.4 324 Gca/Aca 0 +KAZN UCSF GRCh37 1 15287323 15287323 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 6 29 0 ENST00000376030.2:c.370C>T p.Leu124= p.L124= ENST00000376030 NM_201628.2 124 Ctg/Ttg 0 +KBTBD12 UCSF GRCh37 3 127642929 127642929 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 7 115 0 ENST00000405109.1:c.1025C>T p.Ala342Val p.A342V ENST00000405109 342 gCc/gTc 0 +KBTBD7 UCSF GRCh37 13 41768322 41768322 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 262 45 331 0 ENST00000379483.3:c.72G>A p.Arg24= p.R24= ENST00000379483 NM_032138.4 24 agG/agA 0 +KBTBD8 UCSF GRCh37 3 67058550 67058550 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 43 152 0 ENST00000417314.2:c.1547C>T p.Pro516Leu p.P516L ENST00000417314 516 cCa/cTa 0 +KCNA10 UCSF GRCh37 1 111060543 111060543 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 25 155 0 ENST00000369771.2:c.867G>A p.Arg289= p.R289= ENST00000369771 NM_005549.2 289 cgG/cgA 0 +KCNA4 UCSF GRCh37 11 30033372 30033372 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 28 202 0 ENST00000328224.6:c.854C>T p.Pro285Leu p.P285L ENST00000328224 NM_002233.3 285 cCc/cTc 0 +KCNAB1 UCSF GRCh37 3 156009754 156009754 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 18 218 0 ENST00000490337.1:c.276-129651C>T *92* ENST00000490337 NM_172160.2 0 +KCNH6 UCSF GRCh37 17 61615962 61615962 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 13 118 0 ENST00000583023.1:c.1893C>T p.Leu631= p.L631= ENST00000583023 NM_030779.3 631 ctC/ctT 0 +KCNH6 UCSF GRCh37 17 61613308 61613308 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 45 331 0 ENST00000583023.1:c.1380G>A p.Gln460= p.Q460= ENST00000583023 NM_030779.3 460 caG/caA 0 +KCNK16 UCSF GRCh37 6 39290301 39290301 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 28 0 ENST00000425054.2:c.16C>T p.Leu6Phe p.L6F ENST00000425054 NM_001135105.1 6 Ctc/Ttc 0 +KCNK4 UCSF GRCh37 11 64060554 64060554 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 13 66 0 ENST00000539216.1:c.64C>T p.Leu22= p.L22= ENST00000539216 22 Ctg/Ttg 0 +KCNK6 UCSF GRCh37 19 38817562 38817562 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 405 74 524 0 ENST00000263372.3:c.652G>A p.Gly218Ser p.G218S ENST00000263372 NM_004823.1 218 Ggc/Agc 0 +KCNN2 UCSF GRCh37 5 113740307 113740307 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 24 231 0 ENST00000512097.3:c.755C>T p.Ala252Val p.A252V ENST00000512097 252 gCt/gTt 0 +KCNQ4 UCSF GRCh37 1 41304096 41304096 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 373 58 483 0 ENST00000347132.5:c.1989C>T p.Asp663= p.D663= ENST00000347132 NM_004700.3 663 gaC/gaT 0 +KCNS2 UCSF GRCh37 8 99441166 99441166 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 27 227 0 ENST00000287042.4:c.959C>T p.Ala320Val p.A320V ENST00000287042 NM_020697.2 320 gCc/gTc 0 +KCNU1 UCSF GRCh37 8 36666241 36666241 + stop_gained Nonsense_Mutation SNP C C A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 50 179 0 ENST00000399881.3:c.662C>A p.Ser221Ter p.S221* ENST00000399881 NM_001031836.2 221 tCa/tAa 0 +KCTD18 UCSF GRCh37 2 201357981 201357981 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 25 215 0 ENST00000359878.3:c.678G>A p.Arg226= p.R226= ENST00000359878 NM_152387.2 226 cgG/cgA 0 +KCTD8 UCSF GRCh37 4 44449706 44449706 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 17 185 0 ENST00000360029.3:c.835G>A p.Ala279Thr p.A279T ENST00000360029 NM_198353.2 279 Gcc/Acc 0 +KCTD8 UCSF GRCh37 4 44449677 44449677 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 20 168 0 ENST00000360029.3:c.864C>T p.Phe288= p.F288= ENST00000360029 NM_198353.2 288 ttC/ttT 0 +KDELR1 UCSF GRCh37 19 48893746 48893746 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 15 166 0 ENST00000330720.2:c.127G>A p.Val43Met p.V43M ENST00000330720 NM_006801.2 43 Gtg/Atg 0 +KDELR3 UCSF GRCh37 22 38875687 38875687 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 68 245 0 ENST00000409006.3:c.282C>T p.Arg94= p.R94= ENST00000409006 NM_016657.2 94 cgC/cgT 0 +KDM1B UCSF GRCh37 6 18215319 18215319 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 11 74 1 ENST00000297792.5:c.1495C>T p.Gln499Ter p.Q499* ENST00000297792 499 Cag/Tag 0 +KDM2B UCSF GRCh37 12 122013723 122013723 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 49 156 0 ENST00000377071.4:c.313C>T p.Pro105Ser p.P105S ENST00000377071 NM_032590.4 105 Ccc/Tcc 0 +KDM3A UCSF GRCh37 2 86693750 86693750 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 29 258 0 ENST00000409556.1:c.1263G>A p.Lys421= p.K421= ENST00000409556 421 aaG/aaA 0 +KDM5B UCSF GRCh37 1 202715307 202715307 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 30 245 0 ENST00000367265.3:c.2161G>A p.Glu721Lys p.E721K ENST00000367265 NM_006618.3 721 Gaa/Aaa 0 +KDM5C UCSF GRCh37 X 53222430 53222430 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 25 143 0 ENST00000375401.3:c.4402G>A p.Glu1468Lys p.E1468K ENST00000375401 NM_004187.3 1468 Gag/Aag 0 +KIAA0247 UCSF GRCh37 14 70170146 70170146 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 12 82 0 ENST00000342745.4:c.156C>T p.Gly52= p.G52= ENST00000342745 NM_014734.3 52 ggC/ggT 0 +KIAA0284 UCSF GRCh37 14 105349562 105349562 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 13 143 0 ENST00000414716.3:c.768G>A p.Gly256= p.G256= ENST00000414716 NM_001112726.2 256 ggG/ggA 0 +KIAA0408 UCSF GRCh37 6 127767619 127767619 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 380 65 624 0 ENST00000483725.3:c.1845G>A p.Gln615= p.Q615= ENST00000483725 NM_014702.4 615 caG/caA 0 +KIAA0556 UCSF GRCh37 16 27763144 27763144 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 16 181 0 ENST00000261588.4:c.3451G>A p.Asp1151Asn p.D1151N ENST00000261588 NM_015202.2 1151 Gac/Aac 0 +KIAA0664 UCSF GRCh37 17 2607704 2607704 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 397 57 593 0 ENST00000570628.2:c.141C>T p.Gly47= p.G47= ENST00000570628 47 ggC/ggT 0 +KIAA0889 UCSF GRCh37 20 35422950 35422950 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 20 205 0 ENST00000237536.4:c.3535C>T p.Pro1179Ser p.P1179S ENST00000237536 NM_080627.2 1179 Cct/Tct 0 +KIAA0889 UCSF GRCh37 20 35422834 35422834 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 27 158 0 ENST00000237536.4:c.3651C>T p.Leu1217= p.L1217= ENST00000237536 NM_080627.2 1217 ctC/ctT 0 +KIAA1009 UCSF GRCh37 6 84862339 84862339 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 18 166 0 ENST00000403245.3:c.3554G>A p.Gly1185Glu p.G1185E ENST00000403245 NM_014895.2 1185 gGa/gAa 0 +KIAA1009 UCSF GRCh37 6 84836120 84836120 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 357 69 574 0 ENST00000403245.3:c.3982C>T p.Gln1328Ter p.Q1328* ENST00000403245 NM_014895.2 1328 Caa/Taa 0 +KIAA1033 UCSF GRCh37 12 105520060 105520060 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 14 139 0 ENST00000332180.5:c.958G>A p.Gly320Arg p.G320R ENST00000332180 NM_015275.1 320 Gga/Aga 0 +KIAA1109 UCSF GRCh37 4 123160789 123160789 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 22 261 0 ENST00000264501.4:c.3952C>T p.Leu1318Phe p.L1318F ENST00000264501 1318 Ctt/Ttt 0 +KIAA1109 UCSF GRCh37 4 123161284 123161284 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 246 42 417 0 ENST00000264501.4:c.4447G>A p.Glu1483Lys p.E1483K ENST00000264501 1483 Gaa/Aaa 0 +KIAA1109 UCSF GRCh37 4 123185567 123185567 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 40 178 0 ENST00000264501.4:c.7302G>A p.Gln2434= p.Q2434= ENST00000264501 2434 caG/caA 0 +KIAA1217 UCSF GRCh37 10 24790376 24790376 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 15 123 0 ENST00000376454.3:c.1903C>T p.Pro635Ser p.P635S ENST00000376454 NM_019590.3 635 Cca/Tca 0 +KIAA1217 UCSF GRCh37 10 24833394 24833394 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 439 58 333 0 ENST00000376454.3:c.5195C>T p.Pro1732Leu p.P1732L ENST00000376454 NM_019590.3 1732 cCt/cTt 0 +KIAA1217 UCSF GRCh37 10 24809110 24809110 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 27 78 0 ENST00000376454.3:c.2236G>A p.Val746Ile p.V746I ENST00000376454 NM_019590.3 746 Gtt/Att 0 +KIAA1239 UCSF GRCh37 4 37440706 37440706 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 30 246 0 ENST00000309447.5:c.990C>T p.Tyr330= p.Y330= ENST00000309447 NM_001144990.1 330 taC/taT 0 +KIAA1239 UCSF GRCh37 4 37445900 37445900 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 21 197 0 ENST00000309447.5:c.2290C>T p.Leu764= p.L764= ENST00000309447 NM_001144990.1 764 Ctg/Ttg 0 +KIAA1239 UCSF GRCh37 4 37440478 37440478 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 16 138 0 ENST00000309447.5:c.762G>A p.Lys254= p.K254= ENST00000309447 NM_001144990.1 254 aaG/aaA 0 +KIAA1244 UCSF GRCh37 6 138576629 138576629 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 309 50 474 0 ENST00000251691.4:c.827C>T p.Thr276Ile p.T276I ENST00000251691 NM_020340.4 276 aCc/aTc 0 +KIAA1274 UCSF GRCh37 10 72285826 72285826 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 14 89 0 ENST00000263563.6:c.119G>A p.Ser40Asn p.S40N ENST00000263563 NM_014431.2 40 aGc/aAc 0 +KIAA1383 UCSF GRCh37 1 232943021 232943021 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 17 256 0 ENST00000418460.1:c.2252G>A p.Arg751Lys p.R751K ENST00000418460 NM_019090.2 751 aGa/aAa 0 +KIAA1432 UCSF GRCh37 9 5772967 5772967 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 15 151 0 ENST00000414202.2:c.3870C>T p.Ser1290= p.S1290= ENST00000414202 NM_001206557.1 1290 tcC/tcT 0 +KIAA1522 UCSF GRCh37 1 33207765 33207765 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 3 23 0 ENST00000401073.2:c.210C>T p.Ala70= p.A70= ENST00000401073 NM_020888.2 70 gcC/gcT 0 +KIAA1671 UCSF GRCh37 22 25581079 25581079 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 8 58 0 ENST00000358431.3:c.5335G>A p.Asp1779Asn p.D1779N ENST00000358431 NM_001145206.1 1779 Gat/Aat 0 +KIAA1683 UCSF GRCh37 19 18376086 18376086 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 24 123 0 ENST00000392413.4:c.2264G>A p.Cys755Tyr p.C755Y ENST00000392413 NM_001145304.1 755 tGc/tAc 0 +KIAA1731 UCSF GRCh37 11 93402014 93402014 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 57 0 ENST00000325212.6:c.350G>A p.Arg117Lys p.R117K ENST00000325212 117 aGg/aAg 0 +KIAA1797 UCSF GRCh37 9 20789539 20789539 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 6 109 0 ENST00000380249.1:c.1387G>A p.Asp463Asn p.D463N ENST00000380249 NM_017794.3 463 Gac/Aac 0 +KIAA1797 UCSF GRCh37 9 20720401 20720401 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 17 166 0 ENST00000380249.1:c.155G>A p.Trp52Ter p.W52* ENST00000380249 NM_017794.3 52 tGg/tAg 0 +KIAA1984 UCSF GRCh37 9 139694861 139694861 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 196 27 292 0 ENST00000338005.6:c.459C>T p.Asn153= p.N153= ENST00000338005 NM_001039374.4 153 aaC/aaT 0 +KIAA2026 UCSF GRCh37 9 6007765 6007765 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 49 124 0 ENST00000399933.3:c.23G>A p.Gly8Glu p.G8E ENST00000399933 NM_001017969.2 8 gGa/gAa 0 +KIF13A UCSF GRCh37 6 17785781 17785781 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 34 326 0 ENST00000259711.6:c.3453C>T p.Ala1151= p.A1151= ENST00000259711 NM_022113.5 1151 gcC/gcT 0 +KIF14 UCSF GRCh37 1 200559261 200559261 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 12 98 0 ENST00000367350.4:c.2953G>A p.Ala985Thr p.A985T ENST00000367350 NM_014875.2 985 Gca/Aca 0 +KIF16B UCSF GRCh37 20 16359469 16359469 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 43 0 ENST00000408042.1:c.3178C>T p.Leu1060= p.L1060= ENST00000408042 NM_001199866.1 1060 Ctg/Ttg 0 +KIF18B UCSF GRCh37 17 43011932 43011932 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 62 223 0 ENST00000593135.1:c.630C>T p.Arg210= p.R210= ENST00000593135 NM_001265577.1 210 cgC/cgT 0 +KIF1A UCSF GRCh37 2 241660422 241660422 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 12 98 0 ENST00000498729.2:c.4777C>T p.Pro1593Ser p.P1593S ENST00000498729 NM_001244008.1 1593 Ccg/Tcg 0 +KIF1A UCSF GRCh37 2 241685214 241685214 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 67 0 ENST00000498729.2:c.3315G>A p.Val1105= p.V1105= ENST00000498729 NM_001244008.1 1105 gtG/gtA 0 +KIF20B UCSF GRCh37 10 91478491 91478491 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 24 290 0 ENST00000260753.4:c.1296G>A p.Arg432= p.R432= ENST00000260753 NM_016195.2 432 cgG/cgA 0 +KIF21B UCSF GRCh37 1 200978397 200978397 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 23 122 0 ENST00000422435.2:c.261G>A p.Gly87= p.G87= ENST00000422435 NM_001252100.1 87 ggG/ggA 0 +KIF26A UCSF GRCh37 14 104640048 104640048 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 6 38 0 ENST00000423312.2:c.1873G>A p.Gly625Arg p.G625R ENST00000423312 NM_015656.1 625 Gga/Aga 0 +KIRREL UCSF GRCh37 1 158064889 158064889 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 287 53 329 0 ENST00000359209.6:c.2253G>A p.Gln751= p.Q751= ENST00000359209 751 caG/caA 0 +KLF1 UCSF GRCh37 19 12997911 12997911 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 8 56 0 ENST00000264834.4:c.44C>T p.Thr15Ile p.T15I ENST00000264834 NM_006563.3 15 aCc/aTc 0 +KLF16 UCSF GRCh37 19 1863116 1863116 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 3 51 0 ENST00000250916.4:c.381C>T p.His127= p.H127= ENST00000250916 NM_031918.3 127 caC/caT 0 +KLF9 UCSF GRCh37 9 73002854 73002854 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 14 105 0 ENST00000377126.2:c.573C>T p.Thr191= p.T191= ENST00000377126 NM_001206.2 191 acC/acT 0 +KLHDC7A UCSF GRCh37 1 18807887 18807887 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 16 137 0 ENST00000400664.1:c.412C>T p.Pro138Ser p.P138S ENST00000400664 NM_152375.2 138 Cct/Tct 0 +KLHDC9 UCSF GRCh37 1 161068684 161068684 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 13 121 0 ENST00000368011.4:c.359G>A p.Trp120Ter p.W120* ENST00000368011 NM_152366.4 120 tGg/tAg 0 +KLHL1 UCSF GRCh37 13 70293505 70293505 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 16 160 0 ENST00000377844.4:c.2011G>A p.Glu671Lys p.E671K ENST00000377844 NM_020866.2 671 Gaa/Aaa 0 +KLHL15 UCSF GRCh37 X 24006440 24006440 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 161 63 247 0 ENST00000328046.8:c.1413G>A p.Lys471= p.K471= ENST00000328046 NM_030624.2 471 aaG/aaA 0 +KLHL29 UCSF GRCh37 2 23919339 23919339 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 5 54 0 ENST00000486442.1:c.2061C>T p.Thr687= p.T687= ENST00000486442 NM_052920.1 687 acC/acT 0 +KLHL30 UCSF GRCh37 2 239057685 239057685 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 57 169 0 ENST00000409223.1:c.1377G>A p.Lys459= p.K459= ENST00000409223 459 aaG/aaA 0 +KLHL4 UCSF GRCh37 X 86921482 86921482 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 13 4 34 0 ENST00000373114.4:c.2097+1547C>T *699* ENST00000373114 NM_057162.2 0 +KLK14 UCSF GRCh37 19 51581312 51581312 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 16 141 0 ENST00000391802.1:c.756C>T p.Asn252= p.N252= ENST00000391802 NM_022046.4 252 aaC/aaT 0 +KLK9 UCSF GRCh37 19 51509714 51509714 + missense_variant,splice_region_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 24 0 ENST00000250366.6:c.466G>A p.Ala156Thr p.A156T ENST00000250366 NM_012315.1 156 Gcg/Acg 0 +KLRAQ1 UCSF GRCh37 2 48737178 48737178 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 13 108 0 ENST00000294952.8:c.2110G>A p.Ala704Thr p.A704T ENST00000294952 NM_001135629.2 704 Gcc/Acc 0 +KNTC1 UCSF GRCh37 12 123099634 123099634 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 45 321 0 ENST00000333479.7:c.5973+1G>A p.X1991_splice ENST00000333479 NM_014708.4 0 +KPNB1 UCSF GRCh37 17 45755444 45755444 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 177 28 227 0 ENST00000290158.4:c.2136G>A p.Gln712= p.Q712= ENST00000290158 NM_002265.5 712 caG/caA 0 +KRBA1 UCSF GRCh37 7 149422489 149422489 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 24 189 0 ENST00000255992.10:c.1210C>T p.Leu404= p.L404= ENST00000255992 NM_032534.2 404 Ctg/Ttg 0 +KREMEN2 UCSF GRCh37 16 3017392 3017392 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 7 28 0 ENST00000303746.5:c.1045G>A p.Gly349Arg p.G349R ENST00000303746 349 Ggg/Agg 0 +KREMEN2 UCSF GRCh37 16 3017388 3017388 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 3 24 0 ENST00000303746.5:c.1041C>T p.Leu347= p.L347= ENST00000303746 347 ctC/ctT 0 +KRT26 UCSF GRCh37 17 38928333 38928333 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 22 194 0 ENST00000335552.4:c.33G>A p.Arg11= p.R11= ENST00000335552 NM_181539.4 11 agG/agA 0 +KRT36 UCSF GRCh37 17 39642793 39642793 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 4 36 0 ENST00000328119.6:c.1239C>T p.Cys413= p.C413= ENST00000328119 NM_003771.4 413 tgC/tgT 0 +KRT38 UCSF GRCh37 17 39596854 39596854 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 21 231 0 ENST00000246646.3:c.320C>T p.Thr107Ile p.T107I ENST00000246646 NM_006771.3 107 aCc/aTc 0 +KRT74 UCSF GRCh37 12 52967372 52967372 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 23 136 0 ENST00000305620.2:c.190G>A p.Ala64Thr p.A64T ENST00000305620 NM_175053.3 64 Gct/Act 0 +KRT76 UCSF GRCh37 12 53165733 53165733 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 23 232 0 ENST00000332411.2:c.1185G>A p.Arg395= p.R395= ENST00000332411 NM_015848.4 395 agG/agA 0 +KRT84 UCSF GRCh37 12 52771896 52771896 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 4 38 1 ENST00000257951.3:c.1725C>T p.Gly575= p.G575= ENST00000257951 NM_033045.3 575 ggC/ggT 0 +KRTAP13-2 UCSF GRCh37 21 31744248 31744248 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 22 212 0 ENST00000399889.2:c.284C>T p.Thr95Ile p.T95I ENST00000399889 NM_181621.3 95 aCt/aTt 0 +KRTAP4-11 UCSF GRCh37 17 39274332 39274332 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 11 23 0 ENST00000391413.2:c.236G>A p.Cys79Tyr p.C79Y ENST00000391413 NM_033059.3 79 tGc/tAc 0 +KY UCSF GRCh37 3 134369669 134369669 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 12 101 0 ENST00000423778.2:c.134G>A p.Gly45Glu p.G45E ENST00000423778 NM_178554.4 45 gGa/gAa 0 +L3MBTL1 UCSF GRCh37 20 42169455 42169455 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 42 336 0 ENST00000427442.2:c.2328G>A p.Glu776= p.E776= ENST00000427442 776 gaG/gaA 0 +L3MBTL3 UCSF GRCh37 6 130370449 130370449 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 242 31 350 0 ENST00000529410.1:c.125C>T p.Ala42Val p.A42V ENST00000529410 42 gCc/gTc 0 +LAMA3 UCSF GRCh37 18 21481116 21481116 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 5 32 0 ENST00000313654.9:c.6030G>A p.Gln2010= p.Q2010= ENST00000313654 NM_198129.1 2010 caG/caA 0 +LAMA4 UCSF GRCh37 6 112438987 112438987 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 8 99 0 ENST00000230538.7:c.4936G>A p.Glu1646Lys p.E1646K ENST00000230538 NM_001105206.2 1646 Gaa/Aaa 0 +LAMB1 UCSF GRCh37 7 107603473 107603473 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 7 90 0 ENST00000222399.6:c.1734C>T p.Asp578= p.D578= ENST00000222399 NM_002291.2 578 gaC/gaT 0 +LAMB2 UCSF GRCh37 3 49161261 49161261 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 24 198 0 ENST00000418109.1:c.3697C>T p.His1233Tyr p.H1233Y ENST00000418109 NM_002292.3 1233 Cac/Tac 0 +LAMB4 UCSF GRCh37 7 107704388 107704388 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 10 77 0 ENST00000388781.3:c.2879C>T p.Pro960Leu p.P960L ENST00000388781 NM_007356.2 960 cCa/cTa 0 +LAMC2 UCSF GRCh37 1 183197619 183197619 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 16 144 0 ENST00000264144.4:c.1579G>A p.Ala527Thr p.A527T ENST00000264144 NM_005562.2 527 Gcc/Acc 0 +LAMP3 UCSF GRCh37 3 182871876 182871876 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 11 91 0 ENST00000265598.3:c.353C>T p.Pro118Leu p.P118L ENST00000265598 NM_014398.3 118 cCt/cTt 0 +LARGE UCSF GRCh37 22 33712154 33712154 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 3 32 0 ENST00000354992.2:c.1368C>T p.Thr456= p.T456= ENST00000354992 NM_004737.4 456 acC/acT 0 +LARS2 UCSF GRCh37 3 45436039 45436039 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 58 0 ENST00000415258.1:c.94G>A p.Val32Ile p.V32I ENST00000415258 32 Gta/Ata 0 +LAT UCSF GRCh37 16 28997983 28997983 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 94 223 0 ENST00000395461.3:c.454G>A p.Ala152Thr p.A152T ENST00000395461 NM_001014989.1 152 Gcc/Acc 0 +LATS1 UCSF GRCh37 6 150004816 150004816 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 28 194 0 ENST00000253339.5:c.1409G>A p.Gly470Glu p.G470E ENST00000253339 470 gGa/gAa 0 +LATS2 UCSF GRCh37 13 21563229 21563229 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 10 87 0 ENST00000382592.4:c.690C>T p.His230= p.H230= ENST00000382592 NM_014572.2 230 caC/caT 0 +LBR UCSF GRCh37 1 225600175 225600175 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 4 30 0 ENST00000338179.2:c.1065C>T p.Asp355= p.D355= ENST00000338179 NM_194442.2 355 gaC/gaT 0 +LCA5L UCSF GRCh37 21 40778481 40778481 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 214 31 364 0 ENST00000358268.2:c.1340G>A p.Arg447Lys p.R447K ENST00000358268 447 aGa/aAa 0 +LCK UCSF GRCh37 1 32751172 32751172 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 4 32 0 ENST00000336890.5:c.1385C>T p.Pro462Leu p.P462L ENST00000336890 NM_005356.3 462 cCt/cTt 0 +LCMT2 UCSF GRCh37 15 43621541 43621541 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 288 57 428 0 ENST00000305641.5:c.1147C>T p.His383Tyr p.H383Y ENST00000305641 NM_014793.4 383 Cac/Tac 0 +LENG8 UCSF GRCh37 19 54966627 54966627 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 12 47 0 ENST00000326764.5:c.906C>T p.Thr302= p.T302= ENST00000326764 NM_052925.2 302 acC/acT 0 +LEPREL1 UCSF GRCh37 3 189688682 189688682 + splice_acceptor_variant Splice_Site SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 40 134 0 ENST00000319332.5:c.1818-2A>G p.X606_splice ENST00000319332 NM_018192.3 0 +LEPREL1 UCSF GRCh37 3 189713109 189713109 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 7 40 0 ENST00000319332.5:c.603G>A p.Gln201= p.Q201= ENST00000319332 NM_018192.3 201 caG/caA 0 +LEPREL2 UCSF GRCh37 12 6937907 6937907 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 5 22 0 ENST00000396725.2:c.302C>T p.Ser101Phe p.S101F ENST00000396725 101 tCc/tTc 0 +LEPREL4 UCSF GRCh37 17 39968144 39968144 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 19 137 0 ENST00000355468.3:c.24G>A p.Leu8= p.L8= ENST00000355468 8 ctG/ctA 0 +LGALS12 UCSF GRCh37 11 63276249 63276249 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 217 37 284 0 ENST00000340246.5:c.227G>A p.Arg76Lys p.R76K ENST00000340246 76 aGg/aAg 0 +LGALS2 UCSF GRCh37 22 37966674 37966674 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 22 246 0 ENST00000215886.4:c.158C>T p.Ser53Phe p.S53F ENST00000215886 NM_006498.2 53 tCc/tTc 0 +LGALS3BP UCSF GRCh37 17 76969137 76969137 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 25 218 0 ENST00000262776.3:c.544G>A p.Ala182Thr p.A182T ENST00000262776 NM_005567.3 182 Gcc/Acc 0 +LGALS3BP UCSF GRCh37 17 76968372 76968372 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 27 213 0 ENST00000262776.3:c.1044C>T p.Phe348= p.F348= ENST00000262776 NM_005567.3 348 ttC/ttT 0 +LGALS8 UCSF GRCh37 1 236706260 236706260 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 27 264 0 ENST00000526589.1:c.595G>A p.Val199Ile p.V199I ENST00000526589 199 Gtc/Atc 0 +LGR5 UCSF GRCh37 12 71977498 71977498 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 394 71 546 0 ENST00000266674.5:c.1708C>T p.Leu570= p.L570= ENST00000266674 NM_001277226.1 570 Ctg/Ttg 0 +LGSN UCSF GRCh37 6 63990557 63990557 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 23 243 0 ENST00000370657.4:c.899C>T p.Ala300Val p.A300V ENST00000370657 300 gCc/gTc 0 +LHCGR UCSF GRCh37 2 48958435 48958435 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 14 156 0 ENST00000294954.7:c.164C>T p.Ser55Leu p.S55L ENST00000294954 NM_000233.3 55 tCa/tTa 0 +LHX8 UCSF GRCh37 1 75602876 75602876 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 263 44 359 0 ENST00000294638.5:c.197C>T p.Ser66Phe p.S66F ENST00000294638 NM_001001933.1 66 tCc/tTc 0 +LIFR UCSF GRCh37 5 38481941 38481941 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 27 292 0 ENST00000263409.4:c.3050C>T p.Ala1017Val p.A1017V ENST00000263409 NM_002310.5 1017 gCt/gTt 0 +LILRB2 UCSF GRCh37 19 54781751 54781751 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 9 82 0 ENST00000391749.4:c.1301C>T p.Ser434Phe p.S434F ENST00000391749 NM_001278406.1 434 tCc/tTc 0 +LIMA1 UCSF GRCh37 12 50616006 50616006 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 59 148 0 ENST00000394943.3:c.428C>T p.Pro143Leu p.P143L ENST00000394943 143 cCc/cTc 0 +LIMK1 UCSF GRCh37 7 73513509 73513509 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 21 206 0 ENST00000336180.2:c.549C>T p.Asp183= p.D183= ENST00000336180 NM_002314.3 183 gaC/gaT 0 +LIMS2 UCSF GRCh37 2 128400530 128400530 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 5 49 0 ENST00000324938.5:c.549C>T p.Tyr183= p.Y183= ENST00000324938 NM_017980.4 183 taC/taT 0 +LIN7C UCSF GRCh37 11 27520323 27520323 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 15 143 0 ENST00000278193.2:c.467C>T p.Ala156Val p.A156V ENST00000278193 NM_018362.3 156 gCt/gTt 0 +LLGL2 UCSF GRCh37 17 73567161 73567161 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 17 186 0 ENST00000392550.3:c.2156C>T p.Ala719Val p.A719V ENST00000392550 NM_001031803.1 719 gCt/gTt 0 +LMO7 UCSF GRCh37 13 76395518 76395518 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 28 248 0 ENST00000465261.2:c.1714G>A p.Val572Ile p.V572I ENST00000465261 NM_015842.2 572 Gta/Ata 0 +LMOD1 UCSF GRCh37 1 201868704 201868704 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 46 390 0 ENST00000367288.4:c.1437G>A p.Leu479= p.L479= ENST00000367288 NM_012134.2 479 ctG/ctA 0 +LMTK2 UCSF GRCh37 7 97821000 97821000 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 15 95 0 ENST00000297293.5:c.1223C>T p.Thr408Ile p.T408I ENST00000297293 NM_014916.3 408 aCt/aTt 0 +LONP2 UCSF GRCh37 16 48385588 48385588 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 8 65 0 ENST00000285737.4:c.2434C>T p.Pro812Ser p.P812S ENST00000285737 NM_031490.2 812 Cca/Tca 0 +LOX UCSF GRCh37 5 121409721 121409721 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 13 158 0 ENST00000231004.4:c.1022C>T p.Thr341Ile p.T341I ENST00000231004 NM_002317.5 341 aCt/aTt 0 +LOXHD1 UCSF GRCh37 18 44057582 44057582 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 24 164 0 ENST00000300591.6:c.3307+35C>T *1103* ENST00000300591 NM_001145472.2 0 +LPAR4 UCSF GRCh37 X 78010399 78010399 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 25 103 0 ENST00000435339.3:c.33C>T p.Phe11= p.F11= ENST00000435339 NM_005296.2 11 ttC/ttT 0 +LPHN3 UCSF GRCh37 4 62679599 62679599 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 231 33 352 0 ENST00000514591.1:c.1268C>T p.Ser423Phe p.S423F ENST00000514591 423 tCt/tTt 0 +LPIN3 UCSF GRCh37 20 39980780 39980780 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 24 226 0 ENST00000373257.3:c.1283C>T p.Pro428Leu p.P428L ENST00000373257 NM_022896.1 428 cCt/cTt 0 +LPO UCSF GRCh37 17 56343536 56343536 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 28 158 0 ENST00000262290.4:c.1542G>A p.Arg514= p.R514= ENST00000262290 NM_006151.2 514 cgG/cgA 0 +LPP UCSF GRCh37 3 188426154 188426154 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 32 263 0 ENST00000312675.4:c.1213G>A p.Glu405Lys p.E405K ENST00000312675 NM_005578.3 405 Gaa/Aaa 0 +LPPR3 UCSF GRCh37 19 815058 815058 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 9 83 0 ENST00000359894.2:c.427G>A p.Ala143Thr p.A143T ENST00000359894 NM_024888.2 143 Gcc/Acc 0 +LRBA UCSF GRCh37 4 151849989 151849989 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 19 265 0 ENST00000357115.3:c.445G>A p.Ala149Thr p.A149T ENST00000357115 NM_006726.4 149 Gca/Aca 0 +LRIG2 UCSF GRCh37 1 113616265 113616265 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 19 120 0 ENST00000361127.5:c.237C>T p.Ile79= p.I79= ENST00000361127 NM_014813.1 79 atC/atT 0 +LRP1 UCSF GRCh37 12 57594524 57594524 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 12 135 0 ENST00000243077.3:c.10151G>A p.Gly3384Asp p.G3384D ENST00000243077 NM_002332.2 3384 gGt/gAt 0 +LRP1 UCSF GRCh37 12 57539009 57539009 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 291 63 352 0 ENST00000243077.3:c.578-1G>A p.X193_splice ENST00000243077 NM_002332.2 0 +LRP10 UCSF GRCh37 14 23346348 23346348 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 25 182 0 ENST00000359591.4:c.1754C>T p.Ser585Phe p.S585F ENST00000359591 NM_014045.3 585 tCt/tTt 0 +LRP10 UCSF GRCh37 14 23345910 23345910 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 171 21 209 0 ENST00000359591.4:c.1437C>T p.Pro479= p.P479= ENST00000359591 NM_014045.3 479 ccC/ccT 0 +LRP10 UCSF GRCh37 14 23344297 23344297 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 473 284 799 0 ENST00000359591.4:c.249G>A p.Glu83= p.E83= ENST00000359591 NM_014045.3 83 gaG/gaA 0 +LRP12 UCSF GRCh37 8 105503379 105503379 + missense_variant Missense_Mutation SNP C C T 1000g2011may_all_0.0014 P24_Rec2 Untested WXS Illumina HiSeq 115 29 150 0 ENST00000276654.5:c.2102G>A p.Arg701Gln p.R701Q ENST00000276654 NM_013437.4 701 cGa/cAa 0 +LRP6 UCSF GRCh37 12 12419625 12419625 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 177 26 208 0 ENST00000261349.4:c.45G>A p.Val15= p.V15= ENST00000261349 NM_002336.2 15 gtG/gtA 0 +LRRC14B UCSF GRCh37 5 195220 195220 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 4 44 0 ENST00000328278.3:c.1297G>A p.Gly433Ser p.G433S ENST00000328278 NM_001080478.1 433 Ggt/Agt 0 +LRRC16B UCSF GRCh37 14 24531989 24531989 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 11 97 0 ENST00000342740.5:c.2640C>T p.Ser880= p.S880= ENST00000342740 NM_138360.3 880 tcC/tcT 0 +LRRC33 UCSF GRCh37 3 196387682 196387682 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 186 31 265 0 ENST00000328557.4:c.1168G>A p.Glu390Lys p.E390K ENST00000328557 NM_198565.1 390 Gag/Aag 0 +LRRC33 UCSF GRCh37 3 196386848 196386848 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 14 127 0 ENST00000328557.4:c.334C>T p.Leu112= p.L112= ENST00000328557 NM_198565.1 112 Ctg/Ttg 0 +LRRC43 UCSF GRCh37 12 122675926 122675926 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 8 66 0 ENST00000339777.4:c.902-1G>A p.X301_splice ENST00000339777 NM_152759.4 0 +LRRC4B UCSF GRCh37 19 51021391 51021391 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 29 197 0 ENST00000599957.1:c.1579C>T p.Pro527Ser p.P527S ENST00000599957 527 Cct/Tct 0 +LRRC4C UCSF GRCh37 11 40137452 40137452 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 91 320 0 ENST00000278198.2:c.391C>T p.Leu131Phe p.L131F ENST00000278198 131 Ctc/Ttc 0 +LRRC61 UCSF GRCh37 7 150034302 150034302 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 40 253 0 ENST00000359623.4:c.352C>T p.Leu118= p.L118= ENST00000359623 NM_001142928.1 118 Ctg/Ttg 0 +LRRC8A UCSF GRCh37 9 131669632 131669632 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 42 312 0 ENST00000259324.5:c.189C>T p.Asp63= p.D63= ENST00000259324 NM_001127244.1 63 gaC/gaT 0 +LRRC8B UCSF GRCh37 1 90049588 90049588 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 40 330 0 ENST00000330947.2:c.1379C>T p.Ser460Leu p.S460L ENST00000330947 NM_001134476.1 460 tCa/tTa 0 +LRRC8B UCSF GRCh37 1 90049725 90049725 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 23 169 0 ENST00000330947.2:c.1516G>A p.Val506Ile p.V506I ENST00000330947 NM_001134476.1 506 Gta/Ata 0 +LRRC8B UCSF GRCh37 1 90050269 90050269 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 64 526 0 ENST00000330947.2:c.2060G>A p.Ser687Asn p.S687N ENST00000330947 NM_001134476.1 687 aGc/aAc 0 +LRRC8E UCSF GRCh37 19 7963609 7963609 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 272 32 261 0 ENST00000306708.6:c.202C>T p.Pro68Ser p.P68S ENST00000306708 NM_025061.4 68 Ccg/Tcg 0 +LRRFIP1 UCSF GRCh37 2 238683017 238683017 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 9 49 0 ENST00000308482.9:c.1724G>A p.Ser575Asn p.S575N ENST00000308482 NM_001137550.1 575 aGt/aAt 0 +LRRN4 UCSF GRCh37 20 6031501 6031501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 7 103 0 ENST00000378858.4:c.784G>A p.Asp262Asn p.D262N ENST00000378858 NM_152611.4 262 Gac/Aac 0 +LRWD1 UCSF GRCh37 7 102110255 102110255 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 261 46 313 0 ENST00000292616.5:c.1368C>T p.Asp456= p.D456= ENST00000292616 NM_152892.1 456 gaC/gaT 0 +LTA UCSF GRCh37 6 31541433 31541433 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 38 278 0 ENST00000454783.1:c.581G>A p.Ser194Asn p.S194N ENST00000454783 NM_001159740.2 194 aGc/aAc 0 +LTBP1 UCSF GRCh37 2 33590523 33590523 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 32 0 ENST00000404816.2:c.4664G>A p.Gly1555Glu p.G1555E ENST00000404816 1555 gGa/gAa 0 +LTBP4 UCSF GRCh37 19 41128865 41128865 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 70 191 0 ENST00000308370.7:c.3693G>A p.Gln1231= p.Q1231= ENST00000308370 NM_001042544.1 1231 caG/caA 0 +LUZP1 UCSF GRCh37 1 23418977 23418977 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 305 48 390 0 ENST00000302291.4:c.1778G>A p.Ser593Asn p.S593N ENST00000302291 593 aGt/aAt 0 +LY6G6F UCSF GRCh37 6 31675669 31675669 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 19 143 0 ENST00000375832.4:c.404C>T p.Ala135Val p.A135V ENST00000375832 NM_001003693.1 135 gCt/gTt 0 +LYG2 UCSF GRCh37 2 99860569 99860569 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 15 130 0 ENST00000333017.2:c.413C>T p.Ala138Val p.A138V ENST00000333017 NM_175735.3 138 gCc/gTc 0 +LYL1 UCSF GRCh37 19 13211472 13211472 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 737 87 717 0 ENST00000264824.4:c.426G>A p.Glu142= p.E142= ENST00000264824 NM_005583.4 142 gaG/gaA 0 +MAB21L2 UCSF GRCh37 4 151504418 151504418 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 20 186 0 ENST00000317605.4:c.237C>T p.Tyr79= p.Y79= ENST00000317605 NM_006439.4 79 taC/taT 0 +MACF1 UCSF GRCh37 1 39846008 39846008 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 8 87 0 ENST00000545844.1:c.7425G>A p.Gln2475= p.Q2475= ENST00000545844 2475 caG/caA 0 +MAEL UCSF GRCh37 1 166973532 166973532 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 11 101 0 ENST00000367872.4:c.639C>T p.Ile213= p.I213= ENST00000367872 NM_032858.1 213 atC/atT 0 +MAGED1 UCSF GRCh37 X 51640158 51640158 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 11 144 0 ENST00000375695.2:c.1575C>T p.Ala525= p.A525= ENST00000375695 NM_001005333.1 525 gcC/gcT 0 +MAGEF1 UCSF GRCh37 3 184429328 184429328 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 584 91 780 0 ENST00000317897.3:c.282G>A p.Lys94= p.K94= ENST00000317897 NM_022149.4 94 aaG/aaA 0 +MAGEL2 UCSF GRCh37 15 23889682 23889682 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 203 27 277 0 ENST00000532292.1:c.1399G>A p.Glu467Lys p.E467K ENST00000532292 NM_019066.4 467 Gag/Aag 0 +MAGEL2 UCSF GRCh37 15 23890315 23890315 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 33 215 0 ENST00000532292.1:c.766G>A p.Ala256Thr p.A256T ENST00000532292 NM_019066.4 256 Gca/Aca 0 +MAK16 UCSF GRCh37 8 33354807 33354807 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 13 89 0 ENST00000360128.6:c.697G>A p.Asp233Asn p.D233N ENST00000360128 NM_032509.3 233 Gat/Aat 0 +MAOB UCSF GRCh37 X 43655077 43655077 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 27 165 0 ENST00000378069.4:c.677G>A p.Gly226Glu p.G226E ENST00000378069 NM_000898.4 226 gGa/gAa 0 +MAP1A UCSF GRCh37 15 43818123 43818123 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 12 120 0 ENST00000300231.5:c.4452C>T p.Val1484= p.V1484= ENST00000300231 1484 gtC/gtT 0 +MAP2 UCSF GRCh37 2 210560342 210560342 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 82 238 0 ENST00000360351.4:c.3448G>A p.Gly1150Ser p.G1150S ENST00000360351 NM_002374.3 1150 Ggc/Agc 0 +MAP2K1 UCSF GRCh37 15 66727510 66727510 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 12 90 0 ENST00000307102.5:c.226G>A p.Ala76Thr p.A76T ENST00000307102 NM_002755.3 76 Gct/Act 0 +MAP2K1 UCSF GRCh37 15 66782084 66782084 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 273 58 396 0 ENST00000307102.5:c.1051G>A p.Asp351Asn p.D351N ENST00000307102 NM_002755.3 351 Gat/Aat 0 +MAP3K5 UCSF GRCh37 6 136926391 136926391 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 19 45 0 ENST00000359015.4:c.2635C>T p.Pro879Ser p.P879S ENST00000359015 NM_005923.3 879 Ccc/Tcc 0 +MAP3K6 UCSF GRCh37 1 27684060 27684060 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 21 196 0 ENST00000493901.1:c.3089G>A p.Arg1030His p.R1030H ENST00000493901 NM_004672.3 1030 cGt/cAt 0 +MAP3K6 UCSF GRCh37 1 27685280 27685280 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 24 124 0 ENST00000493901.1:c.2503C>T p.Leu835= p.L835= ENST00000493901 NM_004672.3 835 Ctg/Ttg 0 +MAP3K7 UCSF GRCh37 6 91226378 91226378 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 14 117 0 ENST00000369329.3:c.1663G>A p.Asp555Asn p.D555N ENST00000369329 NM_145331.2 555 Gac/Aac 0 +MAP4K3 UCSF GRCh37 2 39487780 39487780 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 18 180 0 ENST00000263881.3:c.2275C>T p.Pro759Ser p.P759S ENST00000263881 NM_003618.3 759 Cca/Tca 0 +MAP7D1 UCSF GRCh37 1 36643628 36643628 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 22 142 0 ENST00000373151.2:c.1534G>A p.Glu512Lys p.E512K ENST00000373151 NM_018067.3 512 Gag/Aag 0 +MAPK11 UCSF GRCh37 22 50705860 50705860 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 3 53 0 ENST00000330651.6:c.357C>T p.Cys119= p.C119= ENST00000330651 NM_002751.5 119 tgC/tgT 0 +MAPK8IP3 UCSF GRCh37 16 1816017 1816017 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 13 137 0 ENST00000250894.4:c.2500C>T p.Pro834Ser p.P834S ENST00000250894 NM_015133.3 834 Cca/Tca 0 +MAPKAP1 UCSF GRCh37 9 128434850 128434850 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 12 83 0 ENST00000265960.3:c.4G>A p.Ala2Thr p.A2T ENST00000265960 NM_001006617.1 2 Gcc/Acc 0 +MARK4 UCSF GRCh37 19 45769492 45769492 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 46 207 0 ENST00000262891.4:c.502G>T p.Ala168Ser p.A168S ENST00000262891 NM_001199867.1 168 Gct/Tct 0 +MARS UCSF GRCh37 12 57882776 57882802 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TAACCCATTTTCCATTCTTGCATCAGA TAACCCATTTTCCATTCTTGCATCAGA AACCCATTTTCCCTTCTTGCCTCAGT NOVEL P24_Rec2 Untested WXS Illumina HiSeq 7 0 ENST00000262027.5:c.110-26_110delinsAACCCATTTTCCCTTCTTGCCTCAGT p.X37_splice ENST00000262027 NM_004990.3 0 +MARS UCSF GRCh37 12 57908940 57908940 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 797 102 262 1 ENST00000262027.5:c.2212G>A p.Ala738Thr p.A738T ENST00000262027 NM_004990.3 738 Gca/Aca 0 +MATN2 UCSF GRCh37 8 98943633 98943633 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 18 148 0 ENST00000520016.1:c.595G>A p.Val199Ile p.V199I ENST00000520016 199 Gta/Ata 0 +MATN2 UCSF GRCh37 8 98973655 98973655 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 19 195 0 ENST00000520016.1:c.855G>A p.Met285Ile p.M285I ENST00000520016 285 atG/atA 0 +MAVS UCSF GRCh37 20 3843000 3843000 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 8 84 0 ENST00000428216.2:c.565C>T p.Pro189Ser p.P189S ENST00000428216 NM_020746.4 189 Cct/Tct 0 +MBOAT7 UCSF GRCh37 19 54684759 54684759 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 63 0 ENST00000245615.1:c.585C>T p.Ala195= p.A195= ENST00000245615 NM_024298.3 195 gcC/gcT 0 +MBP UCSF GRCh37 18 74700469 74700469 + downstream_gene_variant 3'Flank SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 8 81 0 ENST00000582546 0 +MCF2L UCSF GRCh37 13 113718681 113718681 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 12 135 0 ENST00000535094.2:c.553G>A p.Asp185Asn p.D185N ENST00000535094 NM_001112732.2 185 Gac/Aac 0 +MCM3AP UCSF GRCh37 21 47655304 47655304 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 34 245 0 ENST00000397708.1:c.5821G>A p.Ala1941Thr p.A1941T ENST00000397708 1941 Gcg/Acg 0 +MCM3AP UCSF GRCh37 21 47664949 47664949 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 20 193 1 ENST00000397708.1:c.4810G>A p.Glu1604Lys p.E1604K ENST00000397708 1604 Gag/Aag 0 +MCM5 UCSF GRCh37 22 35799454 35799454 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 26 174 0 ENST00000216122.4:c.342G>A p.Arg114= p.R114= ENST00000216122 NM_006739.3 114 cgG/cgA 0 +MCM5 UCSF GRCh37 22 35812631 35812631 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 26 191 0 ENST00000216122.4:c.1414G>A p.Ala472Thr p.A472T ENST00000216122 NM_006739.3 472 Gct/Act 0 +MCM9 UCSF GRCh37 6 119147334 119147334 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 225 39 322 0 ENST00000316316.6:c.1937G>A p.Ser646Asn p.S646N ENST00000316316 NM_017696.2 646 aGt/aAt 0 +MCOLN1 UCSF GRCh37 19 7591692 7591692 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 35 107 0 ENST00000264079.6:c.451C>T p.Arg151Cys p.R151C ENST00000264079 NM_020533.2 151 Cgt/Tgt 0 +MCTP2 UCSF GRCh37 15 94841544 94841544 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 14 117 0 ENST00000357742.4:c.50G>A p.Arg17Lys p.R17K ENST00000357742 NM_018349.3 17 aGg/aAg 0 +MDGA1 UCSF GRCh37 6 37617999 37617999 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 17 85 0 ENST00000434837.3:c.1495C>T p.Leu499= p.L499= ENST00000434837 NM_153487.3 499 Ctg/Ttg 0 +ME3 UCSF GRCh37 11 86158185 86158185 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 18 155 0 ENST00000543262.1:c.1302G>A p.Glu434= p.E434= ENST00000543262 NM_001161586.1 434 gaG/gaA 0 +MECP2 UCSF GRCh37 X 153297923 153297923 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 9 78 0 ENST00000453960.2:c.148G>A p.Glu50Lys p.E50K ENST00000453960 NM_001110792.1 50 Gag/Aag 0 +MECR UCSF GRCh37 1 29542612 29542612 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 5 39 0 ENST00000263702.6:c.311G>A p.Gly104Glu p.G104E ENST00000263702 104 gGa/gAa 0 +MED1 UCSF GRCh37 17 37564974 37564974 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 48 363 0 ENST00000300651.6:c.3500C>T p.Ser1167Phe p.S1167F ENST00000300651 NM_004774.3 1167 tCt/tTt 0 +MED13L UCSF GRCh37 12 116450687 116450687 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 18 174 0 ENST00000281928.3:c.1195C>T p.Pro399Ser p.P399S ENST00000281928 NM_015335.4 399 Cca/Tca 0 +MED26 UCSF GRCh37 19 16687952 16687952 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 41 255 0 ENST00000263390.3:c.689C>T p.Thr230Ile p.T230I ENST00000263390 NM_004831.3 230 aCc/aTc 0 +MED27 UCSF GRCh37 9 134738489 134738489 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 10 80 0 ENST00000292035.5:c.762G>A p.Gln254= p.Q254= ENST00000292035 NM_004269.3 254 caG/caA 0 +MEF2B UCSF GRCh37 19 19257685 19257685 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 12 97 0 ENST00000162023.5:c.542-1G>A p.X181_splice ENST00000162023 0 +MEGF8 UCSF GRCh37 19 42858034 42858034 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 25 243 0 ENST00000334370.4:c.3668G>A p.Gly1223Asp p.G1223D ENST00000334370 NM_001410.2 1223 gGc/gAc 0 +MEGF8 UCSF GRCh37 19 42863080 42863080 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 6 19 0 ENST00000334370.4:c.5116G>A p.Glu1706Lys p.E1706K ENST00000334370 NM_001410.2 1706 Gag/Aag 0 +MEGF8 UCSF GRCh37 19 42848871 42848871 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 22 184 0 ENST00000334370.4:c.1983G>A p.Trp661Ter p.W661* ENST00000334370 NM_001410.2 661 tgG/tgA 0 +MEI1 UCSF GRCh37 22 42144223 42144223 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 8 74 0 ENST00000401548.3:c.1792+1G>A p.X598_splice ENST00000401548 NM_152513.3 0 +MEIS3 UCSF GRCh37 19 47920520 47920520 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 5 21 0 ENST00000561293.1:c.100C>T p.Pro34Ser p.P34S ENST00000561293 34 Ccc/Tcc 0 +MEOX1 UCSF GRCh37 17 41720962 41720962 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 15 85 0 ENST00000318579.4:c.536C>T p.Thr179Ile p.T179I ENST00000318579 NM_001040002.1 179 aCc/aTc 0 +MET UCSF GRCh37 7 116339509 116339509 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 319 108 417 0 ENST00000397752.3:c.371C>T p.Thr124Ile p.T124I ENST00000397752 NM_000245.2 124 aCc/aTc 0 +METRN UCSF GRCh37 16 765688 765688 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 8 22 0 ENST00000568223.2:c.209G>A p.Gly70Asp p.G70D ENST00000568223 NM_024042.2 70 gGc/gAc 0 +MFSD10 UCSF GRCh37 4 2934423 2934423 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 17 109 0 ENST00000329687.4:c.435C>T p.Ala145= p.A145= ENST00000329687 NM_001120.4 145 gcC/gcT 0 +MFSD11 UCSF GRCh37 17 74735066 74735066 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 42 282 0 ENST00000588460.1:c.143G>A p.Gly48Glu p.G48E ENST00000588460 NM_001242534.1 48 gGa/gAa 0 +MGA UCSF GRCh37 15 42054537 42054537 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 18 131 0 ENST00000219905.7:c.7721C>T p.Ser2574Phe p.S2574F ENST00000219905 NM_001164273.1 2574 tCc/tTc 0 +MGAM UCSF GRCh37 7 141724908 141724908 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 19 188 0 ENST00000549489.2:c.941G>A p.Gly314Glu p.G314E ENST00000549489 NM_004668.2 314 gGa/gAa 0 +MIB1 UCSF GRCh37 18 19395702 19395702 + synonymous_variant Silent SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 59 221 0 ENST00000261537.6:c.1605T>C p.His535= p.H535= ENST00000261537 NM_020774.3 535 caT/caC 0 +MICAL2 UCSF GRCh37 11 12183794 12183794 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 37 283 0 ENST00000256194.4:c.92C>T p.Ala31Val p.A31V ENST00000256194 NM_014632.2 31 gCc/gTc 0 +MICAL3 UCSF GRCh37 22 18301123 18301123 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 6 29 0 ENST00000441493.2:c.4304C>T p.Ser1435Phe p.S1435F ENST00000441493 NM_015241.2 1435 tCc/tTc 0 +MICALCL UCSF GRCh37 11 12315524 12315524 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 16 168 0 ENST00000256186.2:c.546C>T p.Val182= p.V182= ENST00000256186 NM_032867.2 182 gtC/gtT 0 +MICB UCSF GRCh37 6 31466001 31466001 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 10 110 0 ENST00000252229.6:c.31G>A p.Ala11Thr p.A11T ENST00000252229 NM_005931.3 11 Gcc/Acc 0 +MLL3 UCSF GRCh37 7 151880171 151880171 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 25 183 0 ENST00000262189.6:c.5153G>A p.Arg1718Lys p.R1718K ENST00000262189 NM_170606.2 1718 aGg/aAg 0 +MLL3 UCSF GRCh37 7 152012300 152012300 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 16 153 0 ENST00000262189.6:c.513G>A p.Lys171= p.K171= ENST00000262189 NM_170606.2 171 aaG/aaA 0 +MLL4 UCSF GRCh37 19 36221339 36221339 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 231 676 1 ENST00000222270.7:c.5173C>T p.Pro1725Ser p.P1725S ENST00000222270 NM_014727.1 1725 Ccc/Tcc 0 +MLL4 UCSF GRCh37 19 36223240 36223240 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 289 56 433 0 ENST00000222270.7:c.5790C>T p.Ser1930= p.S1930= ENST00000222270 NM_014727.1 1930 tcC/tcT 0 +MLL5 UCSF GRCh37 7 104745961 104745961 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 330 66 456 0 ENST00000311117.3:c.2272C>T p.Leu758= p.L758= ENST00000311117 NM_182931.2 758 Cta/Tta 0 +MMEL1 UCSF GRCh37 1 2540829 2540829 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 56 0 ENST00000378412.3:c.484C>T p.Arg162Trp p.R162W ENST00000378412 162 Cgg/Tgg 0 +MMP1 UCSF GRCh37 11 102666337 102666337 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 8 56 0 ENST00000315274.6:c.627G>A p.Glu209= p.E209= ENST00000315274 NM_002421.3 209 gaG/gaA 0 +MMP13 UCSF GRCh37 11 102819875 102819875 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 14 136 0 ENST00000260302.3:c.930C>T p.Arg310= p.R310= ENST00000260302 NM_002427.3 310 cgC/cgT 0 +MMP15 UCSF GRCh37 16 58075765 58075765 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 7 90 0 ENST00000219271.3:c.1155C>T p.Phe385= p.F385= ENST00000219271 NM_002428.2 385 ttC/ttT 0 +MMP3 UCSF GRCh37 11 102712885 102712885 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 9 66 0 ENST00000299855.5:c.625G>A p.Gly209Arg p.G209R ENST00000299855 NM_002422.3 209 Ggg/Agg 0 +MN1 UCSF GRCh37 22 28193613 28193613 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 16 113 0 ENST00000302326.4:c.2919G>A p.Gly973= p.G973= ENST00000302326 NM_002430.2 973 ggG/ggA 0 +MOB3B UCSF GRCh37 9 27359113 27359113 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 25 255 0 ENST00000262244.5:c.540C>T p.Ala180= p.A180= ENST00000262244 NM_024761.4 180 gcC/gcT 0 +MORC1 UCSF GRCh37 3 108829620 108829620 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 5 20 0 ENST00000232603.5:c.130G>A p.Ala44Thr p.A44T ENST00000232603 NM_014429.3 44 Gct/Act 0 +MPHOSPH9 UCSF GRCh37 12 123651312 123651312 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 17 102 0 ENST00000392425.3:c.2025C>T p.Ser675= p.S675= ENST00000392425 675 agC/agT 0 +MPL UCSF GRCh37 1 43817944 43817944 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 18 159 0 ENST00000372470.3:c.1623G>A p.Gln541= p.Q541= ENST00000372470 NM_005373.2 541 caG/caA 0 +MPO UCSF GRCh37 17 56357791 56357791 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 6 63 0 ENST00000225275.3:c.184G>A p.Val62Met p.V62M ENST00000225275 NM_000250.1 62 Gtg/Atg 0 +MPZL3 UCSF GRCh37 11 118104212 118104212 + missense_variant Missense_Mutation SNP C C T snp132_rs116163888 P24_Rec2 Untested WXS Illumina HiSeq 175 30 237 0 ENST00000278949.4:c.644G>A p.Cys215Tyr p.C215Y ENST00000278949 215 tGt/tAt 0 +MRGPRF UCSF GRCh37 11 68773465 68773465 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 14 146 0 ENST00000309099.6:c.313G>A p.Gly105Arg p.G105R ENST00000309099 NM_145015.4 105 Ggg/Agg 0 +MRPL2 UCSF GRCh37 6 43024112 43024112 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 28 224 0 ENST00000388752.3:c.337C>T p.Arg113Trp p.R113W ENST00000388752 NM_015950.3 113 Cgg/Tgg 0 +MRPS18B UCSF GRCh37 6 30587281 30587281 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 31 317 0 ENST00000259873.4:c.90G>A p.Gln30= p.Q30= ENST00000259873 NM_014046.3 30 caG/caA 0 +MRPS35 UCSF GRCh37 12 27863847 27863847 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 21 198 0 ENST00000081029.3:c.71C>T p.Thr24Ile p.T24I ENST00000081029 NM_021821.3 24 aCt/aTt 0 +MRPS5 UCSF GRCh37 2 95770404 95770404 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 228 33 340 0 ENST00000272418.2:c.744G>A p.Gly248= p.G248= ENST00000272418 NM_031902.3 248 ggG/ggA 0 +MS4A15 UCSF GRCh37 11 60531267 60531267 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 231 157 483 0 ENST00000405633.3:c.61G>A p.Gly21Ser p.G21S ENST00000405633 NM_001098835.1 21 Ggc/Agc 0 +MS4A6E UCSF GRCh37 11 60105330 60105330 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0042 P24_Rec2 Untested WXS Illumina HiSeq 85 42 193 0 ENST00000300182.4:c.264C>T p.Asp88= p.D88= ENST00000300182 NM_139249.2 88 gaC/gaT 0 +MSH4 UCSF GRCh37 1 76269570 76269570 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 21 218 0 ENST00000263187.3:c.399G>A p.Lys133= p.K133= ENST00000263187 NM_002440.3 133 aaG/aaA 0 +MSH5 UCSF GRCh37 6 31710893 31710893 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 3 23 0 ENST00000375703.3:c.361G>A p.Glu121Lys p.E121K ENST00000375703 121 Gag/Aag 0 +MSH6 UCSF GRCh37 2 48026834 48026834 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 154 95 325 0 ENST00000234420.5:c.1712G>A p.Gly571Asp p.G571D ENST00000234420 NM_000179.2 571 gGt/gAt 0 +MSH6 UCSF GRCh37 2 48032083 48032083 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 103 61 192 0 ENST00000234420.5:c.3473G>A p.Cys1158Tyr p.C1158Y ENST00000234420 NM_000179.2 1158 tGt/tAt 0 +MSLN UCSF GRCh37 16 817429 817429 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 35 0 ENST00000382862.3:c.1579G>A p.Asp527Asn p.D527N ENST00000382862 NM_013404.4 527 Gac/Aac 0 +MSLN UCSF GRCh37 16 812704 812704 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 163 29 217 0 ENST00000382862.3:c.24C>T p.Pro8= p.P8= ENST00000382862 NM_013404.4 8 ccC/ccT 0 +MTERFD3 UCSF GRCh37 12 107372461 107372461 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 123 16 169 0 ENST00000552029.1:c.32C>T p.Ser11Phe p.S11F ENST00000552029 11 tCc/tTc 0 +MTFMT UCSF GRCh37 15 65298465 65298465 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 22 238 0 ENST00000220058.4:c.878G>A p.Ser293Asn p.S293N ENST00000220058 NM_139242.3 293 aGt/aAt 0 +MTHFD2 UCSF GRCh37 2 74438910 74438910 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 8 46 0 ENST00000394053.2:c.806C>T p.Ala269Val p.A269V ENST00000394053 NM_006636.3 269 gCa/gTa 0 +MTMR3 UCSF GRCh37 22 30403157 30403157 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 8 31 0 ENST00000401950.2:c.726G>A p.Trp242Ter p.W242* ENST00000401950 NM_021090.3 242 tgG/tgA 0 +MTNR1B UCSF GRCh37 11 92714758 92714758 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 49 306 1 ENST00000257068.2:c.369C>T p.Ser123= p.S123= ENST00000257068 NM_005959.3 123 agC/agT 0 +MTUS1 UCSF GRCh37 8 17504501 17504501 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 139 269 0 ENST00000262102.6:c.3589G>A p.Ala1197Thr p.A1197T ENST00000262102 NM_001001924.2 1197 Gca/Aca 0 +MUC1 UCSF GRCh37 1 155161911 155161911 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 14 130 0 ENST00000368395.1:c.222G>A p.Gln74= p.Q74= ENST00000368395 NM_001204285.1 74 caG/caA 0 +MUC16 UCSF GRCh37 19 9073741 9073741 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 20 166 0 ENST00000397910.4:c.13705G>A p.Val4569Ile p.V4569I ENST00000397910 NM_024690.2 4569 Gtt/Att 0 +MUC16 UCSF GRCh37 19 9060954 9060954 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 247 29 276 0 ENST00000397910.4:c.26492C>T p.Pro8831Leu p.P8831L ENST00000397910 NM_024690.2 8831 cCt/cTt 0 +MUC2 UCSF GRCh37 11 1090790 1090790 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 11 126 0 ENST00000441003.2:c.3685C>T p.Leu1229Phe p.L1229F ENST00000441003 NM_002457.2 1229 Ctt/Ttt 0 +MUC2 UCSF GRCh37 11 1096427 1096427 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 24 183 0 ENST00000441003.2:c.6452C>T p.Pro2151Leu p.P2151L ENST00000441003 NM_002457.2 2151 cCc/cTc 0 +MUC5B UCSF GRCh37 11 1250966 1250966 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 30 285 0 ENST00000529681.1:c.1149G>A p.Gly383= p.G383= ENST00000529681 NM_002458.2 383 ggG/ggA 0 +MUC6 UCSF GRCh37 11 1030681 1030681 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 12 103 0 ENST00000421673.2:c.784C>T p.Pro262Ser p.P262S ENST00000421673 NM_005961.2 262 Ccc/Tcc 0 +MUM1 UCSF GRCh37 19 1371047 1371047 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 253 32 227 0 ENST00000344663.3:c.1959C>T p.Ile653= p.I653= ENST00000344663 653 atC/atT 0 +MVP UCSF GRCh37 16 29855860 29855860 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 24 196 0 ENST00000357402.5:c.1681C>T p.Leu561Phe p.L561F ENST00000357402 NM_017458.3 561 Ctc/Ttc 0 +MXRA8 UCSF GRCh37 1 1290246 1290246 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 16 142 0 ENST00000309212.6:c.765C>T p.Phe255= p.F255= ENST00000309212 NM_032348.2 255 ttC/ttT 0 +MYADM UCSF GRCh37 19 54377419 54377419 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 171 31 267 0 ENST00000391769.2:c.636C>T p.Ile212= p.I212= ENST00000391769 NM_001020821.1 212 atC/atT 0 +MYCL1 UCSF GRCh37 1 40363471 40363471 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 28 214 0 ENST00000397332.2:c.758G>A p.Cys253Tyr p.C253Y ENST00000397332 NM_001033082.2 253 tGc/tAc 0 +MYH1 UCSF GRCh37 17 10411982 10411982 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 10 5 24 0 ENST00000226207.5:c.1595G>A p.Gly532Asp p.G532D ENST00000226207 NM_005963.3 532 gGc/gAc 0 +MYH1 UCSF GRCh37 17 10415188 10415188 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 11 26 0 ENST00000226207.5:c.1384G>A p.Val462Ile p.V462I ENST00000226207 NM_005963.3 462 Gtc/Atc 0 +MYH10 UCSF GRCh37 17 8473102 8473102 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 10 114 0 ENST00000360416.3:c.692C>T p.Ala231Val p.A231V ENST00000360416 NM_001256012.1 231 gCa/gTa 0 +MYH11 UCSF GRCh37 16 15818827 15818827 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 18 170 0 ENST00000396324.3:c.3902G>A p.Gly1301Glu p.G1301E ENST00000396324 NM_001040114.1 1301 gGg/gAg 0 +MYH2 UCSF GRCh37 17 10440993 10440993 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 49 0 ENST00000245503.5:c.1576C>T p.Leu526Phe p.L526F ENST00000245503 NM_017534.5 526 Ctc/Ttc 0 +MYH9 UCSF GRCh37 22 36702043 36702043 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 13 116 0 ENST00000216181.5:c.2092C>A p.Leu698Ile p.L698I ENST00000216181 NM_002473.4 698 Ctc/Atc 0 +MYLK UCSF GRCh37 3 123452730 123452730 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 175 24 208 0 ENST00000360304.3:c.1113G>A p.Arg371= p.R371= ENST00000360304 NM_053025.3 371 agG/agA 0 +MYO15A UCSF GRCh37 17 18055258 18055258 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 76 213 1 ENST00000205890.5:c.7886G>A p.Gly2629Asp p.G2629D ENST00000205890 NM_016239.3 2629 gGc/gAc 0 +MYO18A UCSF GRCh37 17 27424829 27424829 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 41 300 1 ENST00000527372.1:c.4079G>A p.Gly1360Glu p.G1360E ENST00000527372 NM_078471.3 1360 gGg/gAg 0 +MYO18A UCSF GRCh37 17 27448665 27448665 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 10 49 0 ENST00000527372.1:c.1271C>T p.Thr424Ile p.T424I ENST00000527372 NM_078471.3 424 aCc/aTc 0 +MYO5A UCSF GRCh37 15 52708393 52708393 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 11 94 0 ENST00000399231.3:c.561C>T p.Ala187= p.A187= ENST00000399231 NM_000259.3 187 gcC/gcT 0 +MYO5B UCSF GRCh37 18 47431193 47431193 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 12 120 0 ENST00000285039.7:c.2420C>T p.Ala807Val p.A807V ENST00000285039 NM_001080467.2 807 gCt/gTt 0 +MYO7A UCSF GRCh37 11 76895733 76895733 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 19 142 0 ENST00000409709.3:c.3476G>A p.Gly1159Asp p.G1159D ENST00000409709 NM_000260.3 1159 gGc/gAc 0 +MYO7B UCSF GRCh37 2 128383042 128383042 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 18 190 0 ENST00000428314.1:c.4069C>T p.Pro1357Ser p.P1357S ENST00000428314 NM_001080527.1 1357 Ccc/Tcc 0 +MYO7B UCSF GRCh37 2 128387376 128387376 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 10 59 0 ENST00000428314.1:c.4703T>C p.Val1568Ala p.V1568A ENST00000428314 NM_001080527.1 1568 gTc/gCc 0 +MYO7B UCSF GRCh37 2 128339968 128339968 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 13 122 0 ENST00000428314.1:c.1290G>A p.Arg430= p.R430= ENST00000428314 NM_001080527.1 430 cgG/cgA 0 +MYO9A UCSF GRCh37 15 72190181 72190181 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 198 35 287 0 ENST00000356056.5:c.4663G>A p.Glu1555Lys p.E1555K ENST00000356056 NM_006901.3 1555 Gag/Aag 0 +MYO9A UCSF GRCh37 15 72196314 72196314 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 9 132 0 ENST00000356056.5:c.2833G>A p.Val945Ile p.V945I ENST00000356056 NM_006901.3 945 Gtt/Att 0 +MYOM1 UCSF GRCh37 18 3215166 3215166 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 14 84 0 ENST00000356443.4:c.56A>G p.Asn19Ser p.N19S ENST00000356443 NM_019856.1 19 aAc/aGc 0 +MYOT UCSF GRCh37 5 137206617 137206617 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 378 59 588 0 ENST00000239926.4:c.277C>T p.Pro93Ser p.P93S ENST00000239926 NM_006790.2 93 Cca/Tca 0 +MYOZ2 UCSF GRCh37 4 120072107 120072107 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 17 198 0 ENST00000307128.5:c.157C>T p.Arg53Cys p.R53C ENST00000307128 NM_016599.4 53 Cgt/Tgt 0 +NAB1 UCSF GRCh37 2 191551996 191551996 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 53 340 0 ENST00000337386.5:c.1328G>A p.Gly443Glu p.G443E ENST00000337386 NM_005966.3 443 gGg/gAg 0 +NACAD UCSF GRCh37 7 45124928 45124928 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 12 55 0 ENST00000490531.2:c.851G>A p.Ser284Asn p.S284N ENST00000490531 NM_001146334.1 284 aGc/aAc 0 +NAGPA UCSF GRCh37 16 5081863 5081863 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 27 183 0 ENST00000312251.3:c.565C>T p.Leu189= p.L189= ENST00000312251 NM_016256.3 189 Ctg/Ttg 0 +NALCN UCSF GRCh37 13 101753175 101753175 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 10 67 0 ENST00000251127.6:c.3122G>A p.Gly1041Glu p.G1041E ENST00000251127 NM_052867.2 1041 gGa/gAa 0 +NASP UCSF GRCh37 1 46073227 46073227 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 4 25 0 ENST00000350030.3:c.644G>A p.Gly215Glu p.G215E ENST00000350030 NM_002482.3 215 gGa/gAa 0 +NAT10 UCSF GRCh37 11 34129869 34129869 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 31 136 0 ENST00000257829.3:c.97G>A p.Gly33Arg p.G33R ENST00000257829 NM_024662.2 33 Gga/Aga 0 +NAV1 UCSF GRCh37 1 201750262 201750262 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 13 151 0 ENST00000367296.4:c.1488G>A p.Gly496= p.G496= ENST00000367296 NM_020443.4 496 ggG/ggA 0 +NAV2 UCSF GRCh37 11 20044667 20044667 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 6 35 0 ENST00000396087.3:c.2838-12838G>A *946* ENST00000396087 NM_001244963.1 0 +NAV3 UCSF GRCh37 12 78400710 78400710 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 10 137 0 ENST00000536525.2:c.1392G>A p.Gln464= p.Q464= ENST00000536525 NM_014903.4 464 caG/caA 0 +NBEA UCSF GRCh37 13 35751142 35751142 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 17 209 0 ENST00000400445.3:c.4564G>A p.Glu1522Lys p.E1522K ENST00000400445 NM_015678.4 1522 Gaa/Aaa 0 +NCAPG2 UCSF GRCh37 7 158454921 158454921 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0014,snp132_rs61746693 P24_Rec2 Untested WXS Illumina HiSeq 145 17 151 0 ENST00000409423.1:c.1954G>A p.Ala652Thr p.A652T ENST00000409423 NM_001281932.1 652 Gcc/Acc 0 +NCKAP1L UCSF GRCh37 12 54920453 54920453 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 58 184 0 ENST00000293373.6:c.2298C>T p.Ile766= p.I766= ENST00000293373 NM_005337.4 766 atC/atT 0 +NCKAP5 UCSF GRCh37 2 133542583 133542583 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 427 66 634 0 ENST00000409261.1:c.1801C>T p.Pro601Ser p.P601S ENST00000409261 NM_207363.2 601 Cct/Tct 0 +NCL UCSF GRCh37 2 232326445 232326445 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 370 51 544 0 ENST00000322723.4:c.419C>T p.Ala140Val p.A140V ENST00000322723 NM_005381.2 140 gCc/gTc 0 +NCL UCSF GRCh37 2 232319968 232319968 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 384 64 581 1 ENST00000322723.4:c.2067C>T p.Gly689= p.G689= ENST00000322723 NM_005381.2 689 ggC/ggT 0 +NCOA6 UCSF GRCh37 20 33328235 33328235 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 20 154 0 ENST00000374796.2:c.5825C>T p.Ser1942Phe p.S1942F ENST00000374796 1942 tCt/tTt 0 +NCOR2 UCSF GRCh37 12 124821445 124821445 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 10 64 0 ENST00000405201.1:c.5969C>T p.Thr1990Ile p.T1990I ENST00000405201 1990 aCc/aTc 0 +NDUFA7 UCSF GRCh37 19 8386193 8386193 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 8 41 0 ENST00000301457.2:c.50G>A p.Gly17Glu p.G17E ENST00000301457 NM_005001.3 17 gGg/gAg 0 +NEDD4L UCSF GRCh37 18 56033398 56033398 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 136 19 177 0 ENST00000400345.3:c.2001G>A p.Trp667Ter p.W667* ENST00000400345 NM_001144967.2 667 tgG/tgA 0 +NEDD9 UCSF GRCh37 6 11213641 11213641 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 32 212 0 ENST00000379446.5:c.332C>T p.Ser111Phe p.S111F ENST00000379446 NM_001271033.1 111 tCc/tTc 0 +NEK5 UCSF GRCh37 13 52701586 52701586 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 28 306 0 ENST00000355568.4:c.33G>A p.Gly11= p.G11= ENST00000355568 NM_199289.1 11 ggG/ggA 0 +NELF UCSF GRCh37 9 140347022 140347022 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 12 115 0 ENST00000371475.3:c.1148C>T p.Thr383Ile p.T383I ENST00000371475 NM_001130969.1 383 aCc/aTc 0 +NES UCSF GRCh37 1 156639827 156639827 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 322 174 541 1 ENST00000368223.3:c.4153G>A p.Glu1385Lys p.E1385K ENST00000368223 NM_006617.1 1385 Gag/Aag 0 +NES UCSF GRCh37 1 156646436 156646436 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 15 114 0 ENST00000368223.3:c.621C>T p.Ala207= p.A207= ENST00000368223 NM_006617.1 207 gcC/gcT 0 +NEURL4 UCSF GRCh37 17 7229659 7229659 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 19 141 0 ENST00000399464.2:c.1208C>T p.Thr403Ile p.T403I ENST00000399464 NM_032442.2 403 aCc/aTc 0 +NEUROG2 UCSF GRCh37 4 113436633 113436633 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 13 113 0 ENST00000313341.3:c.-1-1G>A p.X1_splice ENST00000313341 NM_024019.3 0 +NF1 UCSF GRCh37 17 29559818 29559818 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 88 71 162 0 ENST00000358273.4:c.3415G>A p.Ala1139Thr p.A1139T ENST00000358273 NM_001042492.2 1139 Gca/Aca 0 +NF1 UCSF GRCh37 17 29654615 29654620 + inframe_deletion In_Frame_Del DEL AGAAAT AGAAAT - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 0 ENST00000358273.4:c.5367_5372del p.Glu1789_Ile1791delinsAsp p.E1789_I1791delinsD ENST00000358273 NM_001042492.2 1789 gaAGAAATc/gac 0 +NF2 UCSF GRCh37 22 30077550 30077550 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 37 141 0 ENST00000338641.4:c.1697C>T p.Ser566Phe p.S566F ENST00000338641 NM_000268.3 566 tCc/tTc 0 +NFASC UCSF GRCh37 1 204943842 204943842 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 85 0 ENST00000339876.6:c.1449C>T p.Asn483= p.N483= ENST00000339876 NM_001005388.2 483 aaC/aaT 0 +NFIL3 UCSF GRCh37 9 94172319 94172319 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 418 70 588 0 ENST00000297689.3:c.698G>A p.Arg233Lys p.R233K ENST00000297689 NM_005384.2 233 aGa/aAa 0 +NFKBIA UCSF GRCh37 14 35871683 35871683 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 18 174 0 ENST00000216797.5:c.823G>A p.Glu275Lys p.E275K ENST00000216797 NM_020529.2 275 Gaa/Aaa 0 +NFYA UCSF GRCh37 6 41051812 41051812 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 9 54 0 ENST00000341376.6:c.190G>A p.Val64Ile p.V64I ENST00000341376 NM_002505.4 64 Gtc/Atc 0 +NGDN UCSF GRCh37 14 23946745 23946745 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 23 131 0 ENST00000408901.3:c.904C>T p.Pro302Ser p.P302S ENST00000408901 NM_015514.1 302 Cct/Tct 0 +NHEJ1 UCSF GRCh37 2 220012486 220012486 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 22 86 0 ENST00000356853.5:c.422G>A p.Gly141Asp p.G141D ENST00000356853 NM_024782.2 141 gGc/gAc 0 +NID2 UCSF GRCh37 14 52477742 52477742 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 16 184 1 ENST00000216286.5:c.3574G>A p.Ala1192Thr p.A1192T ENST00000216286 NM_007361.3 1192 Gcc/Acc 0 +NIF3L1 UCSF GRCh37 2 201759992 201759992 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 23 273 0 ENST00000409020.1:c.605G>A p.Gly202Asp p.G202D ENST00000409020 202 gGt/gAt 0 +NIF3L1 UCSF GRCh37 2 201760089 201760089 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 21 210 0 ENST00000409020.1:c.702G>A p.Lys234= p.K234= ENST00000409020 234 aaG/aaA 0 +NIPBL UCSF GRCh37 5 37017264 37017264 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 21 163 0 ENST00000282516.8:c.4920G>A p.Gln1640= p.Q1640= ENST00000282516 NM_133433.3 1640 caG/caA 0 +NKD2 UCSF GRCh37 5 1034924 1034924 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 8 81 0 ENST00000296849.5:c.480C>T p.Asn160= p.N160= ENST00000296849 NM_033120.3 160 aaC/aaT 0 +NKIRAS1 UCSF GRCh37 3 23934754 23934754 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 379 54 523 0 ENST00000443659.2:c.411G>A p.Gln137= p.Q137= ENST00000443659 137 caG/caA 0 +NKPD1 UCSF GRCh37 19 45656002 45656002 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 35 160 0 ENST00000317951.4:c.1693G>A p.Asp565Asn p.D565N ENST00000317951 NM_198478.3 565 Gac/Aac 0 +NLRC4 UCSF GRCh37 2 32476057 32476057 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 41 375 0 ENST00000404025.2:c.876C>T p.Ala292= p.A292= ENST00000404025 292 gcC/gcT 0 +NLRP5 UCSF GRCh37 19 56561867 56561867 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 16 189 0 ENST00000390649.3:c.3041G>A p.Ser1014Asn p.S1014N ENST00000390649 NM_153447.4 1014 aGc/aAc 0 +NLRP8 UCSF GRCh37 19 56466187 56466187 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 14 90 0 ENST00000291971.3:c.763A>G p.Ser255Gly p.S255G ENST00000291971 NM_176811.2 255 Agc/Ggc 0 +NLRP9 UCSF GRCh37 19 56249712 56249712 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 16 189 0 ENST00000332836.2:c.29G>A p.Gly10Asp p.G10D ENST00000332836 NM_176820.2 10 gGc/gAc 0 +NMB UCSF GRCh37 15 85201240 85201240 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 15 162 0 ENST00000394588.3:c.144C>T p.Asn48= p.N48= ENST00000394588 NM_021077.3 48 aaC/aaT 0 +NMT1 UCSF GRCh37 17 43138709 43138709 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 8 72 0 ENST00000592782.1:c.12G>A p.Glu4= p.E4= ENST00000592782 4 gaG/gaA 0 +NNMT UCSF GRCh37 11 114182874 114182874 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 10 106 0 ENST00000535401.1:c.470C>T p.Ala157Val p.A157V ENST00000535401 157 gCt/gTt 0 +NOB1 UCSF GRCh37 16 69776273 69776273 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 5 52 0 ENST00000268802.5:c.1201C>T p.Pro401Ser p.P401S ENST00000268802 NM_014062.2 401 Ccc/Tcc 0 +NOC4L UCSF GRCh37 12 132635830 132635830 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 391 57 522 0 ENST00000330579.1:c.990C>T p.Leu330= p.L330= ENST00000330579 NM_024078.1 330 ctC/ctT 0 +NOD2 UCSF GRCh37 16 50745218 50745218 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 272 50 303 0 ENST00000300589.2:c.1396G>A p.Ala466Thr p.A466T ENST00000300589 NM_022162.1 466 Gcg/Acg 0 +NOL11 UCSF GRCh37 17 65714129 65714129 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.001,1000g2011may_all_0.0024 P24_Rec2 Untested WXS Illumina HiSeq 65 12 86 0 ENST00000253247.4:c.66C>T p.Leu22= p.L22= ENST00000253247 NM_015462.3 22 ctC/ctT 0 +NOL12 UCSF GRCh37 22 38084991 38084991 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 22 123 0 ENST00000359114.4:c.373C>T p.Pro125Ser p.P125S ENST00000359114 NM_024313.2 125 Cca/Tca 0 +NOL6 UCSF GRCh37 9 33466700 33466700 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 37 0 ENST00000297990.4:c.1958G>A p.Ser653Asn p.S653N ENST00000297990 NM_022917.4 653 aGc/aAc 0 +NOTCH2 UCSF GRCh37 1 120510832 120510832 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 7 101 0 ENST00000256646.2:c.1132G>A p.Ala378Thr p.A378T ENST00000256646 NM_024408.3 378 Gca/Aca 0 +NOTCH3 UCSF GRCh37 19 15303236 15303236 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 17 115 0 ENST00000263388.2:c.292G>A p.Val98Met p.V98M ENST00000263388 NM_000435.2 98 Gtg/Atg 0 +NOX4 UCSF GRCh37 11 89073276 89073276 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 3 38 0 ENST00000263317.4:c.1401G>A p.Gln467= p.Q467= ENST00000263317 467 caG/caA 0 +NOXO1 UCSF GRCh37 16 2031163 2031163 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 14 112 0 ENST00000397280.4:c.18C>T p.Tyr6= p.Y6= ENST00000397280 6 taC/taT 0 +NPAS2 UCSF GRCh37 2 101607309 101607309 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 8 82 0 ENST00000335681.5:c.2086G>A p.Val696Ile p.V696I ENST00000335681 NM_002518.3 696 Gtc/Atc 0 +NPEPL1 UCSF GRCh37 20 57268858 57268858 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 202 36 272 0 ENST00000356091.6:c.216C>T p.Asn72= p.N72= ENST00000356091 NM_024663.3 72 aaC/aaT 0 +NPM1 UCSF GRCh37 5 170832397 170832397 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 3 40 0 ENST00000296930.5:c.761G>A p.Ser254Asn p.S254N ENST00000296930 NM_002520.6 254 aGt/aAt 0 +NPR1 UCSF GRCh37 1 153651984 153651984 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 12 73 0 ENST00000368680.3:c.400G>A p.Val134Ile p.V134I ENST00000368680 NM_000906.3 134 Gtc/Atc 0 +NPR3 UCSF GRCh37 5 32780919 32780919 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 19 144 0 ENST00000265074.8:c.1287G>A p.Gln429= p.Q429= ENST00000265074 NM_001204375.1 429 caG/caA 0 +NR1H2 UCSF GRCh37 19 50883108 50883108 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 39 245 0 ENST00000253727.5:c.999C>T p.Thr333= p.T333= ENST00000253727 NM_007121.5 333 acC/acT 0 +NRAP UCSF GRCh37 10 115364464 115364464 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 26 115 0 ENST00000359988.3:c.4131C>T p.Ser1377= p.S1377= ENST00000359988 NM_001261463.1 1377 agC/agT 0 +NRG1 UCSF GRCh37 8 32620750 32620750 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 27 204 0 ENST00000356819.4:c.1284-516C>T *428* ENST00000356819 NM_013956.3 0 +NRG1 UCSF GRCh37 8 31498022 31498022 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 11 91 0 ENST00000520407.1:c.522C>T p.Gly174= p.G174= ENST00000520407 NM_013962.2 174 ggC/ggT 0 +NRL UCSF GRCh37 14 24550553 24550553 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 8 83 0 ENST00000561028.1:c.606G>A p.Arg202= p.R202= ENST00000561028 202 cgG/cgA 0 +NRL UCSF GRCh37 14 24550568 24550568 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 6 70 0 ENST00000561028.1:c.591G>A p.Gln197= p.Q197= ENST00000561028 197 caG/caA 0 +NRXN1 UCSF GRCh37 2 50573959 50573959 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 10 56 0 ENST00000404971.1:c.3485-109851C>T *1162* ENST00000404971 NM_001135659.1 0 +NRXN3 UCSF GRCh37 14 79181181 79181181 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 35 240 0 ENST00000554719.1:c.624C>T p.Tyr208= p.Y208= ENST00000554719 NM_004796.5 208 taC/taT 0 +NSDHL UCSF GRCh37 X 152037444 152037444 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 61 250 0 ENST00000370274.3:c.906C>T p.Tyr302= p.Y302= ENST00000370274 NM_015922.2 302 taC/taT 0 +NT5C2 UCSF GRCh37 10 104865512 104865512 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 18 391 1 ENST00000343289.5:c.340G>A p.Ala114Thr p.A114T ENST00000343289 NM_012229.4 114 Gcc/Acc 0 +NT5M UCSF GRCh37 17 17209926 17209926 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 9 83 0 ENST00000389022.4:c.337G>A p.Glu113Lys p.E113K ENST00000389022 NM_020201.3 113 Gaa/Aaa 0 +NTN4 UCSF GRCh37 12 96131783 96131786 + frameshift_variant Frame_Shift_Del DEL TTCA TTCA - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 7 0 ENST00000343702.4:c.722_725del p.Leu241ProfsTer159 p.L241Pfs*159 ENST00000343702 NM_021229.3 241 cTGAAc/cc 0 +NTN5 UCSF GRCh37 19 49164996 49164996 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 10 84 0 ENST00000270235.4:c.1408G>A p.Glu470Lys p.E470K ENST00000270235 NM_145807.1 470 Gag/Aag 0 +NTRK1 UCSF GRCh37 1 156845411 156845411 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 78 0 ENST00000524377.1:c.1454G>A p.Gly485Glu p.G485E ENST00000524377 NM_002529.3 485 gGg/gAg 0 +NTRK3 UCSF GRCh37 15 88678626 88678626 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 11 49 0 ENST00000360948.2:c.910C>T p.Pro304Ser p.P304S ENST00000360948 NM_001012338.2 304 Ccc/Tcc 0 +NTSR2 UCSF GRCh37 2 11802235 11802235 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 18 137 0 ENST00000306928.5:c.756C>T p.Ser252= p.S252= ENST00000306928 NM_012344.3 252 agC/agT 0 +NUDT6 UCSF GRCh37 4 123843525 123843525 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 18 131 0 ENST00000304430.5:c.203G>A p.Arg68His p.R68H ENST00000304430 NM_007083.4 68 cGc/cAc 0 +NUMA1 UCSF GRCh37 11 71725214 71725214 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 249 51 322 0 ENST00000393695.3:c.3335C>T p.Ala1112Val p.A1112V ENST00000393695 NM_006185.2 1112 gCt/gTt 0 +NUMA1 UCSF GRCh37 11 71730027 71730027 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 5 44 0 ENST00000393695.3:c.585-1G>A p.X195_splice ENST00000393695 NM_006185.2 0 +NUP133 UCSF GRCh37 1 229611474 229611474 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 9 150 0 ENST00000261396.3:c.1762C>T p.Pro588Ser p.P588S ENST00000261396 NM_018230.2 588 Cct/Tct 0 +NUP153 UCSF GRCh37 6 17626056 17626056 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 12 99 0 ENST00000262077.2:c.3884C>T p.Thr1295Ile p.T1295I ENST00000262077 NM_001278210.1 1295 aCc/aTc 0 +NUP153 UCSF GRCh37 6 17669248 17669248 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 8 91 0 ENST00000262077.2:c.1026G>A p.Arg342= p.R342= ENST00000262077 NM_001278210.1 342 agG/agA 0 +NUP210 UCSF GRCh37 3 13364863 13364863 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 17 204 0 ENST00000254508.5:c.4714G>A p.Ala1572Thr p.A1572T ENST00000254508 NM_024923.3 1572 Gct/Act 0 +NUP210L UCSF GRCh37 1 153995709 153995709 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 17 106 0 ENST00000368559.3:c.4187C>T p.Thr1396Ile p.T1396I ENST00000368559 NM_207308.2 1396 aCc/aTc 0 +NUP85 UCSF GRCh37 17 73208118 73208118 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 6 82 0 ENST00000245544.4:c.322G>A p.Val108Ile p.V108I ENST00000245544 NM_024844.3 108 Gtc/Atc 0 +NWD1 UCSF GRCh37 19 16870075 16870075 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 176 186 307 0 ENST00000524140.2:c.1809C>T p.Ser603= p.S603= ENST00000524140 NM_001007525.3 603 tcC/tcT 0 +NXPH2 UCSF GRCh37 2 139428815 139428815 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 193 36 257 0 ENST00000272641.3:c.472G>A p.Val158Met p.V158M ENST00000272641 NM_007226.2 158 Gtg/Atg 0 +NXPH2 UCSF GRCh37 2 139429013 139429013 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 344 44 473 0 ENST00000272641.3:c.274G>A p.Glu92Lys p.E92K ENST00000272641 NM_007226.2 92 Gag/Aag 0 +OBSCN UCSF GRCh37 1 228548193 228548193 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 20 89 0 ENST00000570156.2:c.21533-2084C>T *7178* ENST00000570156 NM_001271223.2 0 +OBSCN UCSF GRCh37 1 228476009 228476009 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 19 113 0 ENST00000570156.2:c.11346C>T p.Ala3782= p.A3782= ENST00000570156 NM_001271223.2 3782 gcC/gcT 0 +OBSL1 UCSF GRCh37 2 220435838 220435838 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 38 80 0 ENST00000404537.1:c.117G>A p.Pro39= p.P39= ENST00000404537 NM_015311.2 39 ccG/ccA 0 +OBSL1 UCSF GRCh37 2 220435388 220435388 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 10 113 0 ENST00000404537.1:c.567C>T p.Gly189= p.G189= ENST00000404537 NM_015311.2 189 ggC/ggT 0 +ODZ1 UCSF GRCh37 X 123519840 123519840 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 16 49 0 ENST00000422452.2:c.5763C>T p.Val1921= p.V1921= ENST00000422452 NM_001163279.1 1921 gtC/gtT 0 +ODZ4 UCSF GRCh37 11 78399263 78399263 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 27 269 0 ENST00000278550.7:c.5096G>A p.Ser1699Asn p.S1699N ENST00000278550 NM_001098816.2 1699 aGc/aAc 0 +OGFR UCSF GRCh37 20 61444254 61444254 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 7 68 0 ENST00000290291.6:c.1287G>A p.Gln429= p.Q429= ENST00000290291 NM_007346.2 429 caG/caA 0 +OLFML3 UCSF GRCh37 1 114524379 114524379 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.00188 P24_Rec2 Untested WXS Illumina HiSeq 193 34 265 0 ENST00000320334.4:c.1209G>A p.Glu403= p.E403= ENST00000320334 NM_020190.2 403 gaG/gaA 0 +OPA1 UCSF GRCh37 3 193335075 193335075 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 82 390 0 ENST00000361908.3:c.556+1G>A p.X186_splice ENST00000361908 NM_130836.2 0 +OPRD1 UCSF GRCh37 1 29189789 29189789 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 17 135 0 ENST00000234961.2:c.1113C>T p.Ala371= p.A371= ENST00000234961 NM_000911.3 371 gcC/gcT 0 +OR10A6 UCSF GRCh37 11 7950088 7950088 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 32 298 0 ENST00000309838.2:c.122G>A p.Gly41Glu p.G41E ENST00000309838 NM_001004461.1 41 gGa/gAa 0 +OR11L1 UCSF GRCh37 1 248004999 248004999 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 10 79 0 ENST00000355784.2:c.200C>T p.Ser67Phe p.S67F ENST00000355784 NM_001001959.1 67 tCc/tTc 0 +OR12D3 UCSF GRCh37 6 29342990 29342990 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 39 282 0 ENST00000396806.3:c.75C>T p.Phe25= p.F25= ENST00000396806 NM_030959.2 25 ttC/ttT 0 +OR13A1 UCSF GRCh37 10 45799010 45799010 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 7 92 0 ENST00000553795.1:c.861G>A p.Gly287= p.G287= ENST00000553795 NM_001004297.2 287 ggG/ggA 0 +OR13C2 UCSF GRCh37 9 107367283 107367283 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 26 259 0 ENST00000542196.1:c.626C>T p.Thr209Ile p.T209I ENST00000542196 NM_001004481.1 209 aCa/aTa 0 +OR1N2 UCSF GRCh37 9 125316357 125316357 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 18 242 0 ENST00000373688.2:c.909C>T p.Asn303= p.N303= ENST00000373688 NM_001004457.1 303 aaC/aaT 0 +OR2C1 UCSF GRCh37 16 3406282 3406282 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 239 33 359 0 ENST00000304936.2:c.342G>A p.Leu114= p.L114= ENST00000304936 NM_012368.2 114 ctG/ctA 0 +OR2L13 UCSF GRCh37 1 248262866 248262866 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 447 63 721 0 ENST00000366478.2:c.189C>T p.Ser63= p.S63= ENST00000366478 NM_175911.2 63 agC/agT 0 +OR2T1 UCSF GRCh37 1 248570216 248570216 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 22 158 0 ENST00000366474.1:c.921C>T p.Tyr307= p.Y307= ENST00000366474 NM_030904.1 307 taC/taT 0 +OR4D2 UCSF GRCh37 17 56247215 56247215 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 383 62 617 0 ENST00000545221.1:c.199G>A p.Ala67Thr p.A67T ENST00000545221 NM_001004707.3 67 Gct/Act 0 +OR4L1 UCSF GRCh37 14 20528749 20528749 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 286 35 432 0 ENST00000315683.1:c.546C>T p.Pro182= p.P182= ENST00000315683 NM_001004717.1 182 ccC/ccT 0 +OR4N5 UCSF GRCh37 14 20612588 20612588 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 238 42 437 0 ENST00000333629.1:c.694G>A p.Gly232Arg p.G232R ENST00000333629 NM_001004724.1 232 Gga/Aga 0 +OR5C1 UCSF GRCh37 9 125551690 125551690 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 27 241 0 ENST00000373680.2:c.479C>T p.Ala160Val p.A160V ENST00000373680 NM_001001923.1 160 gCc/gTc 0 +OR5M3 UCSF GRCh37 11 56237418 56237418 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 33 0 ENST00000312240.2:c.556G>A p.Ala186Thr p.A186T ENST00000312240 NM_001004742.2 186 Gcc/Acc 0 +OR6B3 UCSF GRCh37 2 240984737 240984737 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 10 112 0 ENST00000319423.4:c.753C>T p.Phe251= p.F251= ENST00000319423 NM_173351.1 251 ttC/ttT 0 +OR6C2 UCSF GRCh37 12 55846226 55846226 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 316 40 497 0 ENST00000322678.1:c.229C>T p.Pro77Ser p.P77S ENST00000322678 NM_054105.1 77 Ccc/Tcc 0 +OR6Q1 UCSF GRCh37 11 57799189 57799189 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 278 40 422 0 ENST00000302622.3:c.765C>T p.Phe255= p.F255= ENST00000302622 NM_001005186.2 255 ttC/ttT 0 +OR7E24 UCSF GRCh37 19 9361896 9361896 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 9 77 0 ENST00000456448.1:c.177G>A p.Gly59= p.G59= ENST00000456448 NM_001079935.1 59 ggG/ggA 0 +OR8S1 UCSF GRCh37 12 48920197 48920197 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 299 53 433 0 ENST00000310194.1:c.783G>A p.Met261Ile p.M261I ENST00000310194 NM_001005203.2 261 atG/atA 0 +OR9Q2 UCSF GRCh37 11 57958336 57958336 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 359 64 496 0 ENST00000311591.3:c.374C>T p.Ala125Val p.A125V ENST00000311591 NM_001005283.2 125 gCc/gTc 0 +ORAI1 UCSF GRCh37 12 122079075 122079075 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 21 159 0 ENST00000330079.7:c.438C>T p.Ile146= p.I146= ENST00000330079 NM_032790.3 146 atC/atT 0 +ORMDL2 UCSF GRCh37 12 56212844 56212844 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 486 84 676 0 ENST00000243045.5:c.61G>A p.Gly21Ser p.G21S ENST00000243045 NM_014182.4 21 Ggc/Agc 0 +OSBPL2 UCSF GRCh37 20 60861698 60861698 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 123 20 137 0 ENST00000313733.3:c.1056G>A p.Glu352= p.E352= ENST00000313733 NM_144498.2 352 gaG/gaA 0 +OSMR UCSF GRCh37 5 38919054 38919054 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 507 210 847 0 ENST00000274276.3:c.1475G>A p.Ser492Asn p.S492N ENST00000274276 NM_003999.2 492 aGc/aAc 0 +OSMR UCSF GRCh37 5 38876472 38876472 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 26 279 0 ENST00000274276.3:c.243G>A p.Trp81Ter p.W81* ENST00000274276 NM_003999.2 81 tgG/tgA 0 +OTOF UCSF GRCh37 2 26699183 26699183 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 17 111 0 ENST00000272371.2:c.2679G>A p.Leu893= p.L893= ENST00000272371 NM_194248.2 893 ctG/ctA 0 +OTOP1 UCSF GRCh37 4 4199408 4199408 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 11 116 0 ENST00000296358.4:c.1153C>T p.Pro385Ser p.P385S ENST00000296358 NM_177998.1 385 Ccg/Tcg 0 +OTOR UCSF GRCh37 20 16729077 16729077 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 32 323 0 ENST00000246081.2:c.31G>A p.Gly11Ser p.G11S ENST00000246081 NM_020157.3 11 Ggt/Agt 0 +OTP UCSF GRCh37 5 76926188 76926188 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 8 51 0 ENST00000306422.3:c.879C>T p.Leu293= p.L293= ENST00000306422 NM_032109.2 293 ctC/ctT 0 +OTUD7A UCSF GRCh37 15 31851175 31851175 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 177 62 433 0 ENST00000307050.4:c.547G>A p.Ala183Thr p.A183T ENST00000307050 NM_130901.1 183 Gca/Aca 0 +OXER1 UCSF GRCh37 2 42990903 42990903 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 9 76 0 ENST00000378661.2:c.417C>T p.Phe139= p.F139= ENST00000378661 NM_148962.4 139 ttC/ttT 0 +OXNAD1 UCSF GRCh37 3 16343261 16343261 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 10 89 0 ENST00000285083.5:c.561C>T p.Ile187= p.I187= ENST00000285083 NM_138381.3 187 atC/atT 0 +P2RX5 UCSF GRCh37 17 3593904 3593904 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 252 45 409 0 ENST00000225328.5:c.431G>A p.Gly144Glu p.G144E ENST00000225328 NM_001204519.1 144 gGa/gAa 0 +PA2G4 UCSF GRCh37 12 56501380 56501380 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 19 175 0 ENST00000303305.6:c.469G>A p.Val157Ile p.V157I ENST00000303305 NM_006191.2 157 Gtc/Atc 0 +PADI4 UCSF GRCh37 1 17666209 17666209 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 9 41 0 ENST00000375448.4:c.553C>T p.Leu185= p.L185= ENST00000375448 NM_012387.2 185 Ctg/Ttg 0 +PAK1 UCSF GRCh37 11 77054972 77054972 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 27 251 0 ENST00000356341.3:c.890C>T p.Ala297Val p.A297V ENST00000356341 NM_002576.4 297 gCc/gTc 0 +PANK2 UCSF GRCh37 20 3888757 3888757 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 23 207 0 ENST00000316562.4:c.813G>A p.Lys271= p.K271= ENST00000316562 NM_153638.2 271 aaG/aaA 0 +PAPD7 UCSF GRCh37 5 6746357 6746357 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 21 257 0 ENST00000230859.6:c.526G>A p.Asp176Asn p.D176N ENST00000230859 NM_001171805.1 176 Gat/Aat 0 +PAQR8 UCSF GRCh37 6 52268237 52268237 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 315 53 431 0 ENST00000442253.2:c.226G>A p.Val76Met p.V76M ENST00000442253 NM_133367.4 76 Gtg/Atg 0 +PARD3B UCSF GRCh37 2 206165297 206165297 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 5 35 0 ENST00000358768.2:c.2043G>A p.Lys681= p.K681= ENST00000358768 681 aaG/aaA 0 +PARP10 UCSF GRCh37 8 145051948 145051948 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 20 91 0 ENST00000313028.7:c.2782G>A p.Val928Met p.V928M ENST00000313028 NM_032789.3 928 Gtg/Atg 0 +PATZ1 UCSF GRCh37 22 31741085 31741085 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 40 213 0 ENST00000266269.5:c.504C>T p.Ala168= p.A168= ENST00000266269 NM_014323.2 168 gcC/gcT 0 +PBX3 UCSF GRCh37 9 128725342 128725342 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 6 45 0 ENST00000373489.5:c.1174C>T p.Leu392Phe p.L392F ENST00000373489 NM_006195.5 392 Ctt/Ttt 0 +PCBP1 UCSF GRCh37 2 70315113 70315113 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 11 113 0 ENST00000303577.5:c.238G>A p.Glu80Lys p.E80K ENST00000303577 NM_006196.3 80 Gag/Aag 0 +PCCB UCSF GRCh37 3 135980893 135980893 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 11 70 0 ENST00000469217.1:c.589G>A p.Ala197Thr p.A197T ENST00000469217 NM_001178014.1 197 Gca/Aca 0 +PCCB UCSF GRCh37 3 136046504 136046504 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 31 100 0 ENST00000469217.1:c.1388G>A p.Ser463Asn p.S463N ENST00000469217 NM_001178014.1 463 aGc/aAc 0 +PCDH17 UCSF GRCh37 13 58207455 58207455 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 37 291 0 ENST00000377918.3:c.775G>A p.Gly259Ser p.G259S ENST00000377918 NM_001040429.2 259 Ggt/Agt 0 +PCDHA1 UCSF GRCh37 5 140166180 140166180 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 14 62 0 ENST00000504120.2:c.305G>A p.Cys102Tyr p.C102Y ENST00000504120 NM_018900.2 102 tGc/tAc 0 +PCDHA1 UCSF GRCh37 5 140167511 140167511 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 4 27 0 ENST00000504120.2:c.1636G>A p.Gly546Ser p.G546S ENST00000504120 NM_018900.2 546 Ggc/Agc 0 +PCDHA4 UCSF GRCh37 5 140187587 140187587 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 208 30 346 0 ENST00000530339.1:c.815G>A p.Gly272Glu p.G272E ENST00000530339 NM_018907.2 272 gGa/gAa 0 +PCDHGA2 UCSF GRCh37 5 140720468 140720468 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 8 97 0 ENST00000394576.2:c.1930G>A p.Val644Met p.V644M ENST00000394576 NM_018915.2 644 Gtg/Atg 0 +PCDHGA2 UCSF GRCh37 5 140720761 140720761 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 22 80 0 ENST00000394576.2:c.2223G>A p.Val741= p.V741= ENST00000394576 NM_018915.2 741 gtG/gtA 0 +PCDHGB4 UCSF GRCh37 5 140769026 140769026 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 16 137 0 ENST00000519479.1:c.1575C>T p.Ala525= p.A525= ENST00000519479 NM_003736.2 525 gcC/gcT 0 +PCDHGB6 UCSF GRCh37 5 140789693 140789693 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 10 94 0 ENST00000520790.1:c.1924C>T p.Leu642= p.L642= ENST00000520790 NM_018926.2 642 Ctg/Ttg 0 +PCK1 UCSF GRCh37 20 56138627 56138627 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 4 28 0 ENST00000319441.4:c.805G>A p.Gly269Ser p.G269S ENST00000319441 NM_002591.3 269 Ggt/Agt 0 +PCLO UCSF GRCh37 7 82583161 82583161 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 12 124 0 ENST00000333891.9:c.7108G>A p.Glu2370Lys p.E2370K ENST00000333891 NM_033026.5 2370 Gaa/Aaa 0 +PCNT UCSF GRCh37 21 47805859 47805859 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 12 66 0 ENST00000359568.5:c.3425C>T p.Ser1142Phe p.S1142F ENST00000359568 NM_006031.5 1142 tCc/tTc 0 +PCNX UCSF GRCh37 14 71572113 71572113 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 10 65 0 ENST00000304743.2:c.6257G>A p.Gly2086Glu p.G2086E ENST00000304743 NM_014982.2 2086 gGa/gAa 0 +PDCD6IP UCSF GRCh37 3 33853593 33853593 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 285 37 427 0 ENST00000457054.2:c.239C>T p.Pro80Leu p.P80L ENST00000457054 NM_013374.5 80 cCc/cTc 0 +PDCD6IP UCSF GRCh37 3 33896693 33896693 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 6 20 0 ENST00000457054.2:c.2076C>T p.Phe692= p.F692= ENST00000457054 NM_013374.5 692 ttC/ttT 0 +PDE2A UCSF GRCh37 11 72292464 72292464 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 9 39 0 ENST00000334456.5:c.1982C>T p.Ala661Val p.A661V ENST00000334456 NM_002599.4 661 gCc/gTc 0 +PDE2A UCSF GRCh37 11 72291938 72291938 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 18 90 0 ENST00000334456.5:c.2125G>C p.Val709Leu p.V709L ENST00000334456 NM_002599.4 709 Gtg/Ctg 0 +PDE8A UCSF GRCh37 15 85610248 85610248 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 15 148 0 ENST00000310298.4:c.247C>T p.Leu83Phe p.L83F ENST00000310298 83 Ctt/Ttt 0 +PDGFB UCSF GRCh37 22 39639950 39639950 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 20 124 0 ENST00000331163.6:c.19C>T p.Leu7Phe p.L7F ENST00000331163 NM_002608.2 7 Ctc/Ttc 0 +PDGFC UCSF GRCh37 4 157689065 157689065 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 23 283 0 ENST00000502773.1:c.781G>A p.Glu261Lys p.E261K ENST00000502773 NM_016205.2 261 Gaa/Aaa 0 +PDHA2 UCSF GRCh37 4 96762127 96762127 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 17 71 0 ENST00000295266.4:c.826G>A p.Gly276Arg p.G276R ENST00000295266 NM_005390.4 276 Ggg/Agg 0 +PDHB UCSF GRCh37 3 58416454 58416454 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 13 89 0 ENST00000302746.6:c.519G>A p.Lys173= p.K173= ENST00000302746 NM_000925.3 173 aaG/aaA 0 +PDHX UCSF GRCh37 11 34938345 34938345 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 6 50 0 ENST00000227868.4:c.143G>A p.Ser48Asn p.S48N ENST00000227868 48 aGc/aAc 0 +PDIA5 UCSF GRCh37 3 122808018 122808018 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 13 105 0 ENST00000316218.7:c.46G>A p.Val16Ile p.V16I ENST00000316218 NM_006810.3 16 Gtc/Atc 0 +PDLIM3 UCSF GRCh37 4 186435434 186435434 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 28 284 0 ENST00000284770.5:c.388G>A p.Gly130Ser p.G130S ENST00000284770 NM_014476.5 130 Ggc/Agc 0 +PDXDC1 UCSF GRCh37 16 15125643 15125643 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 7 94 0 ENST00000396410.4:c.1451G>A p.Ser484Asn p.S484N ENST00000396410 NM_015027.2 484 aGc/aAc 0 +PDZD7 UCSF GRCh37 10 102778682 102778682 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 6 89 0 ENST00000370215.3:c.1221C>T p.Arg407= p.R407= ENST00000370215 NM_024895.4 407 cgC/cgT 0 +PDZRN4 UCSF GRCh37 12 41967428 41967428 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 240 40 356 0 ENST00000402685.2:c.2847C>T p.His949= p.H949= ENST00000402685 NM_001164595.1 949 caC/caT 0 +PEAK1 UCSF GRCh37 15 77425452 77425452 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 91 275 0 ENST00000560626.2:c.3972G>A p.Trp1324Ter p.W1324* ENST00000560626 1324 tgG/tgA 0 +PEBP1 UCSF GRCh37 12 118577290 118577290 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 7 98 0 ENST00000261313.2:c.280G>A p.Gly94Ser p.G94S ENST00000261313 NM_002567.2 94 Ggc/Agc 0 +PEX6 UCSF GRCh37 6 42941759 42941759 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 390 71 524 0 ENST00000304611.8:c.1112G>A p.Ser371Asn p.S371N ENST00000304611 NM_000287.3 371 aGt/aAt 0 +PFKFB4 UCSF GRCh37 3 48587613 48587613 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 173 28 229 0 ENST00000232375.3:c.152G>A p.Gly51Asp p.G51D ENST00000232375 NM_004567.2 51 gGc/gAc 0 +PGBD2 UCSF GRCh37 1 249211522 249211522 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 370 51 540 0 ENST00000329291.5:c.739C>T p.Pro247Ser p.P247S ENST00000329291 NM_170725.2 247 Cct/Tct 0 +PGM2 UCSF GRCh37 4 37831716 37831716 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 12 91 0 ENST00000381967.4:c.212C>T p.Ser71Phe p.S71F ENST00000381967 NM_018290.3 71 tCt/tTt 0 +PHACTR3 UCSF GRCh37 20 58152623 58152623 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 15 120 0 ENST00000359926.3:c.60C>T p.Gly20= p.G20= ENST00000359926 NM_001199505.1 20 ggC/ggT 0 +PHACTR3 UCSF GRCh37 20 58330317 58330317 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 30 181 0 ENST00000371015.1:c.439C>T p.Leu147= p.L147= ENST00000371015 NM_080672.4 147 Ctg/Ttg 0 +PHF1 UCSF GRCh37 6 33382758 33382758 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 7 27 0 ENST00000374516.3:c.1076G>A p.Gly359Glu p.G359E ENST00000374516 NM_024165.2 359 gGa/gAa 0 +PHF12 UCSF GRCh37 17 27251136 27251136 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 30 257 0 ENST00000332830.4:c.506C>T p.Ser169Phe p.S169F ENST00000332830 NM_001033561.1 169 tCc/tTc 0 +PHF12 UCSF GRCh37 17 27240296 27240296 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 17 85 0 ENST00000332830.4:c.1294-1G>A p.X432_splice ENST00000332830 NM_001033561.1 0 +PHF19 UCSF GRCh37 9 123620309 123620309 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 30 256 0 ENST00000373896.3:c.1656G>A p.Gly552= p.G552= ENST00000373896 NM_015651.1 552 ggG/ggA 0 +PHF2 UCSF GRCh37 9 96407928 96407928 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 19 102 0 ENST00000359246.4:c.317C>T p.Ala106Val p.A106V ENST00000359246 NM_005392.3 106 gCc/gTc 0 +PHF20 UCSF GRCh37 20 34458943 34458943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 19 142 0 ENST00000374012.3:c.989G>A p.Arg330Lys p.R330K ENST00000374012 330 aGg/aAg 0 +PHF8 UCSF GRCh37 X 54043128 54043128 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 23 81 0 ENST00000357988.5:c.604G>A p.Ala202Thr p.A202T ENST00000357988 NM_001184896.1 202 Gct/Act 0 +PHGDH UCSF GRCh37 1 120254733 120254733 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 22 138 0 ENST00000369409.4:c.88G>A p.Val30Met p.V30M ENST00000369409 NM_006623.3 30 Gtg/Atg 0 +PHKA2 UCSF GRCh37 X 18912438 18912438 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 16 132 0 ENST00000379942.4:c.3421G>A p.Val1141Met p.V1141M ENST00000379942 NM_000292.2 1141 Gtg/Atg 0 +PHKG1 UCSF GRCh37 7 56149333 56149333 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 4 25 0 ENST00000452681.2:c.1004G>A p.Gly335Glu p.G335E ENST00000452681 NM_001258459.1 335 gGg/gAg 0 +PI4KB UCSF GRCh37 1 151280276 151280276 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 13 89 0 ENST00000368875.2:c.992C>T p.Pro331Leu p.P331L ENST00000368875 NM_002651.2 331 cCt/cTt 0 +PIAS3 UCSF GRCh37 1 145578398 145578398 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 315 49 462 0 ENST00000393045.2:c.361C>T p.Gln121Ter p.Q121* ENST00000393045 NM_006099.3 121 Cag/Tag 0 +PIEZO2 UCSF GRCh37 18 10691261 10691261 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 12 113 0 ENST00000503781.3:c.6972C>T p.Thr2324= p.T2324= ENST00000503781 NM_022068.2 2324 acC/acT 0 +PIGL UCSF GRCh37 17 16120652 16120652 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 27 205 0 ENST00000225609.5:c.112G>A p.Gly38Arg p.G38R ENST00000225609 NM_004278.3 38 Gga/Aga 0 +PIGZ UCSF GRCh37 3 196674425 196674425 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 7 54 0 ENST00000412723.1:c.1343C>T p.Ala448Val p.A448V ENST00000412723 NM_025163.3 448 gCc/gTc 0 +PIK3C2A UCSF GRCh37 11 17172087 17172087 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 23 262 1 ENST00000265970.7:c.1285G>A p.Asp429Asn p.D429N ENST00000265970 NM_002645.2 429 Gac/Aac 0 +PIK3R1 UCSF GRCh37 5 67522637 67522637 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 132 23 196 0 ENST00000274335.5:c.134G>A p.Gly45Glu p.G45E ENST00000274335 45 gGa/gAa 0 +PIK3R4 UCSF GRCh37 3 130398229 130398229 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 66 198 0 ENST00000356763.3:c.4007C>T p.Ala1336Val p.A1336V ENST00000356763 NM_014602.2 1336 gCc/gTc 0 +PITPNM3 UCSF GRCh37 17 6406878 6406878 + synonymous_variant Silent SNP C C A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 12 56 0 ENST00000262483.8:c.243G>T p.Pro81= p.P81= ENST00000262483 NM_031220.3 81 ccG/ccT 0 +PKD1 UCSF GRCh37 16 2142185 2142185 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 12 96 0 ENST00000262304.4:c.11274C>T p.Leu3758= p.L3758= ENST00000262304 NM_001009944.2 3758 ctC/ctT 0 +PKHD1L1 UCSF GRCh37 8 110535461 110535461 + splice_acceptor_variant Splice_Site SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 15 54 0 ENST00000378402.5:c.12331-1G>T p.X4111_splice ENST00000378402 NM_177531.4 0 +PKIG UCSF GRCh37 20 43243344 43243344 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 8 45 0 ENST00000372889.1:c.147G>A p.Gly49= p.G49= ENST00000372889 NM_001281444.1 49 ggG/ggA 0 +PKN2 UCSF GRCh37 1 89298952 89298952 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 33 300 0 ENST00000370521.3:c.2776G>A p.Asp926Asn p.D926N ENST00000370521 NM_006256.2 926 Gac/Aac 0 +PKP1 UCSF GRCh37 1 201292273 201292273 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 53 0 ENST00000263946.3:c.1699G>A p.Ala567Thr p.A567T ENST00000263946 NM_000299.3 567 Gcc/Acc 0 +PKP4 UCSF GRCh37 2 159498999 159498999 + missense_variant,splice_region_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 5 41 0 ENST00000389759.3:c.1697T>C p.Val566Ala p.V566A ENST00000389759 NM_003628.3 566 gTg/gCg 0 +PLB1 UCSF GRCh37 2 28823694 28823694 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 12 79 0 ENST00000327757.5:c.2493C>T p.Val831= p.V831= ENST00000327757 NM_153021.4 831 gtC/gtT 0 +PLBD2 UCSF GRCh37 12 113806940 113806940 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 20 186 0 ENST00000280800.3:c.310G>A p.Gly104Ser p.G104S ENST00000280800 NM_173542.3 104 Ggc/Agc 0 +PLCD3 UCSF GRCh37 17 43194151 43194151 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 6 44 0 ENST00000322765.5:c.1261C>T p.Leu421= p.L421= ENST00000322765 NM_133373.3 421 Ctg/Ttg 0 +PLCD4 UCSF GRCh37 2 219496999 219496999 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 3 31 0 ENST00000450993.2:c.1413C>T p.Pro471= p.P471= ENST00000450993 NM_032726.3 471 ccC/ccT 0 +PLCH2 UCSF GRCh37 1 2435776 2435776 + 3_prime_UTR_variant 3'UTR SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.0138 P24_Rec2 Untested WXS Illumina HiSeq 211 36 249 0 ENST00000449969.1:c.*710G>A *237* ENST00000449969 0 +PLD5 UCSF GRCh37 1 242271036 242271036 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 19 136 0 ENST00000536534.2:c.1176G>A p.Thr392= p.T392= ENST00000536534 392 acG/acA 0 +PLEC UCSF GRCh37 8 144996554 144996554 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 6 61 0 ENST00000322810.4:c.7846G>A p.Val2616Met p.V2616M ENST00000322810 NM_201380.2 2616 Gtg/Atg 0 +PLEC UCSF GRCh37 8 145003922 145003922 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 82 0 ENST00000322810.4:c.3226G>A p.Asp1076Asn p.D1076N ENST00000322810 NM_201380.2 1076 Gac/Aac 0 +PLEKHA7 UCSF GRCh37 11 16823347 16823347 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 8 42 0 ENST00000355661.3:c.2175G>A p.Val725= p.V725= ENST00000355661 725 gtG/gtA 0 +PLEKHA8 UCSF GRCh37 7 30118238 30118238 + missense_variant Missense_Mutation SNP T T G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 61 170 0 ENST00000449726.1:c.1395T>G p.Asp465Glu p.D465E ENST00000449726 NM_001197027.1 465 gaT/gaG 0 +PLEKHG4 UCSF GRCh37 16 67318226 67318226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 22 212 0 ENST00000360461.5:c.1558G>A p.Glu520Lys p.E520K ENST00000360461 NM_001129727.1 520 Gag/Aag 0 +PLEKHG5 UCSF GRCh37 1 6579521 6579521 + downstream_gene_variant 3'Flank SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 17 141 0 ENST00000377705 NM_024654.4 0 +PLEKHH1 UCSF GRCh37 14 68029130 68029130 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 28 195 0 ENST00000329153.5:c.782G>A p.Arg261Lys p.R261K ENST00000329153 NM_020715.2 261 aGa/aAa 0 +PLEKHJ1 UCSF GRCh37 19 2235921 2235921 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 23 134 0 ENST00000589097.1:c.162+1G>A p.X54_splice ENST00000589097 0 +PLEKHM1 UCSF GRCh37 17 43555292 43555292 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 34 0 ENST00000430334.3:c.270G>A p.Trp90Ter p.W90* ENST00000430334 NM_014798.2 90 tgG/tgA 0 +PLEKHM2 UCSF GRCh37 1 16054173 16054173 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 13 104 0 ENST00000375799.3:c.1606G>A p.Glu536Lys p.E536K ENST00000375799 NM_015164.2 536 Gag/Aag 0 +PLIN4 UCSF GRCh37 19 4512416 4512416 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 79 259 0 ENST00000301286.3:c.1514C>T p.Thr505Ile p.T505I ENST00000301286 NM_001080400.1 505 aCc/aTc 0 +PLIN4 UCSF GRCh37 19 4504779 4504779 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 16 75 0 ENST00000301286.3:c.3766C>T p.Leu1256= p.L1256= ENST00000301286 NM_001080400.1 1256 Ctg/Ttg 0 +PLXNA2 UCSF GRCh37 1 208272276 208272276 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 14 83 0 ENST00000367033.3:c.1646C>T p.Pro549Leu p.P549L ENST00000367033 NM_025179.3 549 cCt/cTt 0 +PLXNA4 UCSF GRCh37 7 131888179 131888179 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 16 117 0 ENST00000359827.3:c.2299-1G>A p.X767_splice ENST00000359827 0 +PLXNB3 UCSF GRCh37 X 153040007 153040007 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 31 132 0 ENST00000538966.1:c.3880C>T p.Leu1294Phe p.L1294F ENST00000538966 NM_001163257.1 1294 Ctc/Ttc 0 +PLXNB3 UCSF GRCh37 X 153041605 153041605 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 6 35 0 ENST00000538966.1:c.4734G>A p.Val1578= p.V1578= ENST00000538966 NM_001163257.1 1578 gtG/gtA 0 +PNPLA6 UCSF GRCh37 19 7616255 7616255 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 12 82 0 ENST00000414982.3:c.2219C>T p.Thr740Ile p.T740I ENST00000414982 NM_001166111.1 740 aCc/aTc 0 +PNPO UCSF GRCh37 17 46023984 46023984 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 23 127 0 ENST00000225573.4:c.622G>A p.Gly208Ser p.G208S ENST00000225573 NM_018129.3 208 Ggc/Agc 0 +PODXL UCSF GRCh37 7 131196090 131196090 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 19 142 0 ENST00000378555.3:c.203C>T p.Thr68Ile p.T68I ENST00000378555 68 aCt/aTt 0 +POGLUT1 UCSF GRCh37 3 119196263 119196263 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 6 36 0 ENST00000295588.4:c.424G>A p.Glu142Lys p.E142K ENST00000295588 NM_152305.2 142 Gag/Aag 0 +POLD1 UCSF GRCh37 19 50918726 50918726 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 13 83 0 ENST00000440232.2:c.2596G>A p.Asp866Asn p.D866N ENST00000440232 NM_002691.3 866 Gac/Aac 0 +POLE UCSF GRCh37 12 133250267 133250267 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 30 252 0 ENST00000320574.5:c.1253C>T p.Pro418Leu p.P418L ENST00000320574 NM_006231.2 418 cCt/cTt 0 +POLG UCSF GRCh37 15 89859994 89859994 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 114 349 0 ENST00000268124.5:c.3708G>A p.Gln1236= p.Q1236= ENST00000268124 NM_001126131.1 1236 caG/caA 0 +POLK UCSF GRCh37 5 74886260 74886260 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 11 85 0 ENST00000241436.4:c.1351C>T p.Leu451Phe p.L451F ENST00000241436 NM_016218.2 451 Ctt/Ttt 0 +POLQ UCSF GRCh37 3 121238772 121238772 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 4 41 0 ENST00000264233.5:c.1414C>T p.Leu472Phe p.L472F ENST00000264233 NM_199420.3 472 Ctt/Ttt 0 +POLQ UCSF GRCh37 3 121192275 121192275 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 33 296 0 ENST00000264233.5:c.6465G>A p.Lys2155= p.K2155= ENST00000264233 NM_199420.3 2155 aaG/aaA 0 +POLR1A UCSF GRCh37 2 86276299 86276299 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 8 65 0 ENST00000263857.6:c.2459C>T p.Thr820Ile p.T820I ENST00000263857 820 aCc/aTc 0 +POLR3B UCSF GRCh37 12 106786810 106786810 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 19 173 1 ENST00000228347.4:c.725C>T p.Ala242Val p.A242V ENST00000228347 NM_018082.5 242 gCc/gTc 0 +POLR3C UCSF GRCh37 1 145608438 145608438 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 253 42 345 0 ENST00000334163.3:c.369G>A p.Lys123= p.K123= ENST00000334163 NM_006468.6 123 aaG/aaA 0 +POLR3G UCSF GRCh37 5 89791543 89791543 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 198 22 350 0 ENST00000399107.1:c.297G>A p.Trp99Ter p.W99* ENST00000399107 NM_006467.2 99 tgG/tgA 0 +POLR3GL UCSF GRCh37 1 145457265 145457265 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 21 182 0 ENST00000369314.1:c.427G>A p.Asp143Asn p.D143N ENST00000369314 NM_032305.1 143 Gat/Aat 0 +POLRMT UCSF GRCh37 19 619040 619040 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 30 0 ENST00000588649.2:c.3224G>A p.Gly1075Asp p.G1075D ENST00000588649 NM_005035.3 1075 gGc/gAc 0 +PORCN UCSF GRCh37 X 48370884 48370884 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 17 64 0 ENST00000326194.6:c.544G>A p.Gly182Ser p.G182S ENST00000326194 NM_203475.1 182 Ggc/Agc 0 +POU1F1 UCSF GRCh37 3 87313588 87313588 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 17 164 0 ENST00000344265.3:c.367C>T p.Leu123Phe p.L123F ENST00000344265 NM_001122757.1 123 Ctt/Ttt 0 +POU2AF1 UCSF GRCh37 11 111225225 111225225 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 7 61 0 ENST00000393067.3:c.532C>T p.Pro178Ser p.P178S ENST00000393067 NM_006235.2 178 Ccg/Tcg 0 +POU2F1 UCSF GRCh37 1 167358932 167358932 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 88 267 0 ENST00000367866.2:c.921C>T p.Asp307= p.D307= ENST00000367866 NM_002697.3 307 gaC/gaT 0 +PPAP2C UCSF GRCh37 19 281472 281472 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 8 63 0 ENST00000327790.3:c.846G>A p.Leu282= p.L282= ENST00000327790 NM_177543.2 282 ctG/ctA 0 +PPAPDC2 UCSF GRCh37 9 4662876 4662876 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 14 136 0 ENST00000381883.2:c.501G>A p.Met167Ile p.M167I ENST00000381883 NM_203453.3 167 atG/atA 0 +PPARGC1A UCSF GRCh37 4 23814383 23814383 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 536 93 841 0 ENST00000264867.2:c.2006G>A p.Arg669Lys p.R669K ENST00000264867 NM_013261.3 669 aGg/aAg 0 +PPCS UCSF GRCh37 1 42925543 42925543 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 20 201 0 ENST00000372561.3:c.882G>A p.Lys294= p.K294= ENST00000372561 NM_024664.2 294 aaG/aaA 0 +PPIC UCSF GRCh37 5 122359692 122359692 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 34 279 0 ENST00000306442.4:c.517G>A p.Val173Met p.V173M ENST00000306442 NM_000943.4 173 Gtg/Atg 0 +PPIG UCSF GRCh37 2 170493243 170493243 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 7 77 0 ENST00000260970.3:c.1475G>A p.Arg492Lys p.R492K ENST00000260970 NM_004792.2 492 aGg/aAg 0 +PPL UCSF GRCh37 16 4934223 4934223 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 42 276 0 ENST00000345988.2:c.4433G>A p.Gly1478Glu p.G1478E ENST00000345988 NM_002705.4 1478 gGg/gAg 0 +PPL UCSF GRCh37 16 4945402 4945402 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 7 64 0 ENST00000345988.2:c.1102G>A p.Glu368Lys p.E368K ENST00000345988 NM_002705.4 368 Gag/Aag 0 +PPL UCSF GRCh37 16 4935581 4935581 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 477 61 577 0 ENST00000345988.2:c.3075C>T p.Gly1025= p.G1025= ENST00000345988 NM_002705.4 1025 ggC/ggT 0 +PPP1R10 UCSF GRCh37 6 30569755 30569755 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 11 81 0 ENST00000376511.2:c.2671G>A p.Gly891Arg p.G891R ENST00000376511 NM_002714.3 891 Ggg/Agg 0 +PPP1R12A UCSF GRCh37 12 80199970 80199970 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 5 48 0 ENST00000450142.2:c.1799C>T p.Ser600Phe p.S600F ENST00000450142 NM_002480.2 600 tCt/tTt 0 +PPP1R12C UCSF GRCh37 19 55603275 55603275 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 4 17 0 ENST00000263433.3:c.2163G>A p.Arg721= p.R721= ENST00000263433 NM_017607.3 721 agG/agA 0 +PPP1R1B UCSF GRCh37 17 37791937 37791937 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 19 113 0 ENST00000254079.4:c.523G>A p.Asp175Asn p.D175N ENST00000254079 NM_032192.3 175 Gat/Aat 0 +PPP1R1B UCSF GRCh37 17 37792068 37792068 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 29 274 0 ENST00000254079.4:c.566-1G>A p.X189_splice ENST00000254079 NM_032192.3 0 +PPP1R9A UCSF GRCh37 7 94539523 94539523 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 19 154 0 ENST00000433360.1:c.98C>T p.Thr33Ile p.T33I ENST00000433360 NM_001166160.1 33 aCc/aTc 0 +PPP2R1A UCSF GRCh37 19 52723488 52723488 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 25 180 0 ENST00000322088.6:c.1349G>A p.Trp450Ter p.W450* ENST00000322088 NM_014225.5 450 tGg/tAg 0 +PPP4R1 UCSF GRCh37 18 9550083 9550083 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 14 165 0 ENST00000400556.3:c.2514G>A p.Trp838Ter p.W838* ENST00000400556 NM_001042388.2 838 tgG/tgA 0 +PPP6R2 UCSF GRCh37 22 50860692 50860692 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 10 114 0 ENST00000395741.3:c.858C>T p.Gly286= p.G286= ENST00000395741 286 ggC/ggT 0 +PQLC1 UCSF GRCh37 18 77679347 77679347 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 12 36 0 ENST00000397778.2:c.445T>C p.Cys149Arg p.C149R ENST00000397778 NM_025078.4 149 Tgc/Cgc 0 +PQLC2 UCSF GRCh37 1 19652012 19652012 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 18 94 0 ENST00000375153.3:c.318C>T p.Val106= p.V106= ENST00000375153 NM_001040125.1 106 gtC/gtT 0 +PRAM1 UCSF GRCh37 19 8563584 8563584 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 19 178 0 ENST00000423345.4:c.1108C>T p.Pro370Ser p.P370S ENST00000423345 370 Ccg/Tcg 0 +PRB2 UCSF GRCh37 12 11546488 11546488 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 4 25 0 ENST00000389362.4:c.524C>T p.Ser175Phe p.S175F ENST00000389362 NM_006248.3 175 tCt/tTt 0 +PRDM1 UCSF GRCh37 6 106547225 106547225 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 9 75 0 ENST00000369096.4:c.462G>A p.Glu154= p.E154= ENST00000369096 NM_001198.3 154 gaG/gaA 0 +PRELID2 UCSF GRCh37 5 145198978 145198978 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 15 160 0 ENST00000334744.4:c.208-1G>A p.X70_splice ENST00000334744 NM_182960.2 0 +PREX1 UCSF GRCh37 20 47274678 47274678 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 251 686 0 ENST00000371941.3:c.1970C>T p.Ala657Val p.A657V ENST00000371941 NM_020820.3 657 gCt/gTt 0 +PRKAA2 UCSF GRCh37 1 57169883 57169883 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 377 58 544 0 ENST00000371244.4:c.1028C>T p.Ala343Val p.A343V ENST00000371244 NM_006252.3 343 gCc/gTc 0 +PRKAR2B UCSF GRCh37 7 106793633 106793633 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 18 214 0 ENST00000265717.4:c.855C>T p.Arg285= p.R285= ENST00000265717 NM_002736.2 285 cgC/cgT 0 +PRKCE UCSF GRCh37 2 46411943 46411943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 252 148 555 0 ENST00000306156.3:c.2137G>A p.Asp713Asn p.D713N ENST00000306156 NM_005400.2 713 Gac/Aac 0 +PRKCE UCSF GRCh37 2 45879539 45879539 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 6 41 0 ENST00000306156.3:c.300C>T p.Ile100= p.I100= ENST00000306156 NM_005400.2 100 atC/atT 0 +PRKD2 UCSF GRCh37 19 47207845 47207845 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 28 163 0 ENST00000433867.1:c.573C>T p.Ala191= p.A191= ENST00000433867 NM_001079881.1 191 gcC/gcT 0 +PRKDC UCSF GRCh37 8 48746825 48746825 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 17 118 0 ENST00000314191.2:c.8081C>T p.Ser2694Leu p.S2694L ENST00000314191 NM_006904.6 2694 tCa/tTa 0 +PRKDC UCSF GRCh37 8 48686847 48686847 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 20 204 0 ENST00000314191.2:c.12271C>T p.Gln4091Ter p.Q4091* ENST00000314191 NM_006904.6 4091 Caa/Taa 0 +PRKX UCSF GRCh37 X 3631222 3631222 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 4 14 0 ENST00000262848.5:c.73G>A p.Asp25Asn p.D25N ENST00000262848 NM_005044.4 25 Gac/Aac 0 +PRMT5 UCSF GRCh37 14 23393582 23393582 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 155 27 216 0 ENST00000324366.8:c.1096G>A p.Ala366Thr p.A366T ENST00000324366 NM_006109.3 366 Gca/Aca 0 +PRMT6 UCSF GRCh37 1 107599844 107599844 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 18 144 0 ENST00000370078.1:c.507C>T p.Ser169= p.S169= ENST00000370078 169 tcC/tcT 0 +PRMT7 UCSF GRCh37 16 68349966 68349966 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 3 78 0 ENST00000339507.5:c.84G>A p.Gln28= p.Q28= ENST00000339507 28 caG/caA 0 +PRODH2 UCSF GRCh37 19 36303727 36303727 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 10 96 0 ENST00000301175.3:c.209G>A p.Gly70Glu p.G70E ENST00000301175 NM_021232.1 70 gGa/gAa 0 +PRODH2 UCSF GRCh37 19 36303717 36303717 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 17 101 0 ENST00000301175.3:c.219G>A p.Gln73= p.Q73= ENST00000301175 NM_021232.1 73 caG/caA 0 +PROS1 UCSF GRCh37 3 93595954 93595954 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 28 222 0 ENST00000394236.3:c.1726G>A p.Glu576Lys p.E576K ENST00000394236 NM_000313.3 576 Gaa/Aaa 0 +PROSER1 UCSF GRCh37 13 39586978 39586978 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 9 57 0 ENST00000352251.3:c.2411C>T p.Pro804Leu p.P804L ENST00000352251 NM_025138.4 804 cCc/cTc 0 +PROX1 UCSF GRCh37 1 214170574 214170574 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 17 98 0 ENST00000366958.4:c.696G>A p.Lys232= p.K232= ENST00000366958 NM_001270616.1 232 aaG/aaA 0 +PRPH UCSF GRCh37 12 49690754 49690754 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 13 36 0 ENST00000257860.4:c.785C>T p.Thr262Met p.T262M ENST00000257860 NM_006262.3 262 aCg/aTg 0 +PRR11 UCSF GRCh37 17 57272127 57272127 + synonymous_variant Silent SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 32 91 0 ENST00000262293.4:c.655T>C p.Leu219= p.L219= ENST00000262293 NM_018304.3 219 Tta/Cta 0 +PRR12 UCSF GRCh37 19 50098074 50098074 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 36 364 0 ENST00000418929.2:c.482C>T p.Pro161Leu p.P161L ENST00000418929 NM_020719.1 161 cCc/cTc 0 +PRR14L UCSF GRCh37 22 32081545 32081545 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 360 65 583 1 ENST00000327423.6:c.6424G>A p.Glu2142Lys p.E2142K ENST00000327423 NM_173566.2 2142 Gaa/Aaa 0 +PRR5L UCSF GRCh37 11 36458955 36458955 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 366 68 534 0 ENST00000378867.3:c.373C>T p.Leu125= p.L125= ENST00000378867 NM_024841.4 125 Ctg/Ttg 0 +PRRC2A UCSF GRCh37 6 31593028 31593028 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 22 187 0 ENST00000376033.2:c.544G>A p.Ala182Thr p.A182T ENST00000376033 NM_004638.3 182 Gct/Act 0 +PRRC2C UCSF GRCh37 1 171535927 171535927 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 12 142 0 ENST00000338920.4:c.6497C>T p.Thr2166Ile p.T2166I ENST00000338920 NM_015172.3 2166 aCt/aTt 0 +PRRC2C UCSF GRCh37 1 171509943 171509943 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 44 289 0 ENST00000338920.4:c.3332G>A p.Ser1111Asn p.S1111N ENST00000338920 NM_015172.3 1111 aGt/aAt 0 +PRRT3 UCSF GRCh37 3 9987933 9987933 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 23 151 0 ENST00000412055.1:c.2924C>T p.Ser975Phe p.S975F ENST00000412055 NM_207351.3 975 tCc/tTc 0 +PRRX1 UCSF GRCh37 1 170695366 170695366 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 29 190 0 ENST00000239461.6:c.423G>A p.Trp141Ter p.W141* ENST00000239461 NM_022716.2 141 tgG/tgA 0 +PRSS27 UCSF GRCh37 16 2764279 2764279 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 160 22 202 0 ENST00000302641.3:c.295G>A p.Gly99Arg p.G99R ENST00000302641 NM_031948.3 99 Gga/Aga 0 +PRSS36 UCSF GRCh37 16 31155070 31155070 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 161 19 200 0 ENST00000268281.4:c.809G>A p.Arg270Lys p.R270K ENST00000268281 NM_173502.4 270 aGa/aAa 0 +PRSS57 UCSF GRCh37 19 691942 691942 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 16 58 0 ENST00000329267.7:c.297C>T p.Thr99= p.T99= ENST00000329267 NM_214710.3 99 acC/acT 0 +PRUNE2 UCSF GRCh37 9 79323744 79323744 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 429 65 600 0 ENST00000376718.3:c.3446G>A p.Ser1149Asn p.S1149N ENST00000376718 NM_015225.2 1149 aGt/aAt 0 +PRUNE2 UCSF GRCh37 9 79320935 79320935 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 46 336 0 ENST00000376718.3:c.6255G>A p.Glu2085= p.E2085= ENST00000376718 NM_015225.2 2085 gaG/gaA 0 +PRX UCSF GRCh37 19 40899917 40899917 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 4 31 0 ENST00000324001.7:c.4342C>T p.Pro1448Ser p.P1448S ENST00000324001 NM_181882.2 1448 Cca/Tca 0 +PSD UCSF GRCh37 10 104172277 104172277 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 18 176 0 ENST00000020673.5:c.1609G>A p.Glu537Lys p.E537K ENST00000020673 NM_001270966.1 537 Gag/Aag 0 +PSD2 UCSF GRCh37 5 139189372 139189372 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 22 84 0 ENST00000274710.3:c.347C>T p.Pro116Leu p.P116L ENST00000274710 NM_032289.2 116 cCa/cTa 0 +PSEN2 UCSF GRCh37 1 227083262 227083262 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 42 210 0 ENST00000366783.3:c.1329C>T p.Ser443= p.S443= ENST00000366783 NM_000447.2 443 tcC/tcT 0 +PSMB5 UCSF GRCh37 14 23502717 23502717 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 235 35 315 0 ENST00000361611.6:c.365G>A p.Cys122Tyr p.C122Y ENST00000361611 NM_002797.3 122 tGt/tAt 0 +PSMB6 UCSF GRCh37 17 4700831 4700831 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 36 250 1 ENST00000270586.3:c.269C>T p.Ala90Val p.A90V ENST00000270586 NM_002798.2 90 gCt/gTt 0 +PSMD3 UCSF GRCh37 17 38146367 38146367 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 7 23 0 ENST00000264639.4:c.898C>T p.Leu300= p.L300= ENST00000264639 NM_002809.3 300 Ctg/Ttg 0 +PSPC1 UCSF GRCh37 13 20325505 20325505 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 19 97 0 ENST00000338910.4:c.873G>A p.Glu291= p.E291= ENST00000338910 NM_001042414.2 291 gaG/gaA 0 +PSTPIP1 UCSF GRCh37 15 77328155 77328155 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 17 84 0 ENST00000558012.1:c.998C>T p.Thr333Ile p.T333I ENST00000558012 NM_003978.3 333 aCc/aTc 0 +PTAR1 UCSF GRCh37 9 72374784 72374784 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 15 119 0 ENST00000340434.4:c.71G>A p.Arg24Lys p.R24K ENST00000340434 NM_001099666.1 24 aGg/aAg 0 +PTBP2 UCSF GRCh37 1 97217025 97217025 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 10 110 0 ENST00000426398.2:c.84G>A p.Pro28= p.P28= ENST00000426398 NM_021190.2 28 ccG/ccA 0 +PTCH1 UCSF GRCh37 9 98222034 98222034 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 15 90 0 ENST00000331920.6:c.2735G>A p.Gly912Asp p.G912D ENST00000331920 NM_000264.3 912 gGc/gAc 0 +PTEN UCSF GRCh37 10 89692877 89692877 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 146 49 394 0 ENST00000371953.3:c.361G>A p.Ala121Thr p.A121T ENST00000371953 NM_000314.4 121 Gca/Aca 0 +PTEN UCSF GRCh37 10 89711875 89711875 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 somatic WXS Sanger Illumina HiSeq 49 15 134 0 ENST00000371953.3:c.493G>A p.Gly165Arg p.G165R ENST00000371953 NM_000314.4 165 Gga/Aga 0 +PTGDR UCSF GRCh37 14 52735256 52735256 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 211 45 319 0 ENST00000306051.2:c.724G>A p.Asp242Asn p.D242N ENST00000306051 NM_000953.2 242 Gac/Aac 0 +PTK2B UCSF GRCh37 8 27287616 27287616 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 617 78 603 0 ENST00000397501.1:c.558C>T p.Phe186= p.F186= ENST00000397501 NM_173174.2 186 ttC/ttT 0 +PTPDC1 UCSF GRCh37 9 96860280 96860280 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 25 296 0 ENST00000288976.3:c.1426C>T p.Pro476Ser p.P476S ENST00000288976 NM_001253829.1 476 Ccc/Tcc 0 +PTPN14 UCSF GRCh37 1 214557450 214557450 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 25 128 0 ENST00000366956.5:c.1748C>T p.Ala583Val p.A583V ENST00000366956 NM_005401.4 583 gCc/gTc 0 +PTPN21 UCSF GRCh37 14 88946277 88946277 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.000,1000g2011may_all_0.0020 P24_Rec2 Untested WXS Illumina HiSeq 67 14 71 0 ENST00000556564.1:c.1498G>A p.Ala500Thr p.A500T ENST00000556564 NM_007039.3 500 Gca/Aca 0 +PTPN23 UCSF GRCh37 3 47451032 47451032 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 12 92 0 ENST00000265562.4:c.1923G>A p.Arg641= p.R641= ENST00000265562 NM_015466.2 641 cgG/cgA 0 +PTPRD UCSF GRCh37 9 8485797 8485797 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 10 87 0 ENST00000356435.5:c.3020C>T p.Pro1007Leu p.P1007L ENST00000356435 1007 cCc/cTc 0 +PTPRH UCSF GRCh37 19 55693383 55693383 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 337 61 511 0 ENST00000376350.3:c.3198+1G>A p.X1066_splice ENST00000376350 NM_002842.3 0 +PTPRH UCSF GRCh37 19 55715304 55715304 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 37 262 0 ENST00000376350.3:c.732G>A p.Gln244= p.Q244= ENST00000376350 NM_002842.3 244 caG/caA 0 +PTPRM UCSF GRCh37 18 8069855 8069855 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 24 186 0 ENST00000580170.1:c.1304G>A p.Trp435Ter p.W435* ENST00000580170 NM_001105244.1 435 tGg/tAg 0 +PUM1 UCSF GRCh37 1 31425201 31425201 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 5 58 0 ENST00000426105.2:c.2601G>A p.Gln867= p.Q867= ENST00000426105 867 caG/caA 0 +PUS7 UCSF GRCh37 7 105148954 105148954 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 67 203 0 ENST00000356362.2:c.6G>A p.Glu2= p.E2= ENST00000356362 NM_019042.3 2 gaG/gaA 0 +PUS7 UCSF GRCh37 7 105105815 105105815 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 59 226 0 ENST00000356362.2:c.1572C>T p.Ile524= p.I524= ENST00000356362 NM_019042.3 524 atC/atT 0 +PUSL1 UCSF GRCh37 1 1244534 1244534 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 19 144 0 ENST00000379031.5:c.204G>A p.Gly68= p.G68= ENST00000379031 NM_153339.1 68 ggG/ggA 0 +PVRL4 UCSF GRCh37 1 161042643 161042643 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 171 24 225 0 ENST00000368012.3:c.1341G>A p.Thr447= p.T447= ENST00000368012 NM_030916.2 447 acG/acA 0 +PXN UCSF GRCh37 12 120661972 120661972 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 15 114 0 ENST00000267257.7:c.222C>T p.Ser74= p.S74= ENST00000267257 NM_001243756.1 74 tcC/tcT 0 +PYCARD UCSF GRCh37 16 31212947 31212947 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 12 86 0 ENST00000247470.9:c.547G>A p.Glu183Lys p.E183K ENST00000247470 NM_013258.4 183 Gag/Aag 0 +QRICH1 UCSF GRCh37 3 49095184 49095184 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 30 213 0 ENST00000395443.2:c.449C>T p.Ser150Phe p.S150F ENST00000395443 NM_198880.1 150 tCc/tTc 0 +RAB11B UCSF GRCh37 19 8467013 8467013 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 9 74 0 ENST00000328024.6:c.280G>A p.Ala94Thr p.A94T ENST00000328024 NM_004218.3 94 Gcc/Acc 0 +RAB25 UCSF GRCh37 1 156040048 156040048 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 263 49 341 0 ENST00000361084.5:c.612G>A p.Gly204= p.G204= ENST00000361084 NM_020387.2 204 ggG/ggA 0 +RAB33B UCSF GRCh37 4 140394125 140394125 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 9 216 0 ENST00000305626.5:c.535G>A p.Ala179Thr p.A179T ENST00000305626 NM_031296.1 179 Gct/Act 0 +RAB39 UCSF GRCh37 11 107832857 107832857 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 30 256 0 ENST00000320578.2:c.413C>T p.Thr138Ile p.T138I ENST00000320578 NM_017516.1 138 aCa/aTa 0 +RAB41 UCSF GRCh37 X 69502395 69502395 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 62 108 0 ENST00000276066.4:c.134C>T p.Ser45Phe p.S45F ENST00000276066 NM_001032726.2 45 tCc/tTc 0 +RAB6A UCSF GRCh37 11 73441816 73441816 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 11 42 0 ENST00000310653.6:c.123C>T p.Thr41= p.T41= ENST00000310653 NM_002869.4 41 acC/acT 0 +RAB7A UCSF GRCh37 3 128514235 128514235 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 23 161 0 ENST00000265062.3:c.25C>T p.Leu9= p.L9= ENST00000265062 NM_004637.5 9 Ctg/Ttg 0 +RAB8A UCSF GRCh37 19 16229055 16229055 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 12 107 0 ENST00000300935.3:c.144G>A p.Arg48= p.R48= ENST00000300935 NM_005370.4 48 agG/agA 0 +RAB9B UCSF GRCh37 X 103080138 103080138 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 29 129 0 ENST00000243298.2:c.577G>A p.Gly193Ser p.G193S ENST00000243298 NM_016370.2 193 Ggc/Agc 0 +RAB9B UCSF GRCh37 X 103080687 103080687 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 14 195 0 ENST00000243298.2:c.28G>A p.Val10Ile p.V10I ENST00000243298 NM_016370.2 10 Gtc/Atc 0 +RABEP1 UCSF GRCh37 17 5253909 5253909 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 149 21 257 0 ENST00000262477.6:c.948G>A p.Leu316= p.L316= ENST00000262477 NM_004703.4 316 ctG/ctA 0 +RAD52 UCSF GRCh37 12 1042140 1042140 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 333 47 381 0 ENST00000358495.3:c.84+1G>A p.X28_splice ENST00000358495 NM_134424.2 0 +RADIL UCSF GRCh37 7 4841284 4841284 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 23 0 ENST00000399583.3:c.2842G>A p.Gly948Arg p.G948R ENST00000399583 NM_018059.4 948 Gga/Aga 0 +RAET1G UCSF GRCh37 6 150239357 150239357 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 16 87 0 ENST00000367360.2:c.795C>T p.Pro265= p.P265= ENST00000367360 NM_001001788.2 265 ccC/ccT 0 +RAG1 UCSF GRCh37 11 36596534 36596534 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 12 108 0 ENST00000299440.5:c.1680C>T p.Phe560= p.F560= ENST00000299440 NM_000448.2 560 ttC/ttT 0 +RAI14 UCSF GRCh37 5 34823332 34823332 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 28 260 0 ENST00000515799.1:c.1394G>A p.Arg465Gln p.R465Q ENST00000515799 NM_001145525.1 465 cGa/cAa 0 +RALGAPA2 UCSF GRCh37 20 20506958 20506958 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 15 149 0 ENST00000202677.7:c.3631C>T p.Leu1211= p.L1211= ENST00000202677 NM_020343.3 1211 Ctg/Ttg 0 +RAPGEF5 UCSF GRCh37 7 22186635 22186635 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 428 54 456 0 ENST00000344041.6:c.1428C>T p.Asn476= p.N476= ENST00000344041 NM_012294.3 476 aaC/aaT 0 +RARS UCSF GRCh37 5 167944905 167944905 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 19 229 0 ENST00000231572.3:c.1711G>A p.Glu571Lys p.E571K ENST00000231572 NM_002887.3 571 Gaa/Aaa 0 +RASAL3 UCSF GRCh37 19 15564017 15564017 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 14 104 0 ENST00000343625.7:c.2571C>T p.Ser857= p.S857= ENST00000343625 NM_022904.1 857 tcC/tcT 0 +RASGRF1 UCSF GRCh37 15 79307703 79307703 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 13 160 0 ENST00000419573.3:c.1792G>A p.Glu598Lys p.E598K ENST00000419573 NM_002891.4 598 Gaa/Aaa 0 +RASGRF2 UCSF GRCh37 5 80366380 80366380 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 13 129 0 ENST00000265080.4:c.613G>A p.Asp205Asn p.D205N ENST00000265080 NM_006909.2 205 Gac/Aac 0 +RASGRF2 UCSF GRCh37 5 80497218 80497218 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 12 169 0 ENST00000265080.4:c.2863G>A p.Asp955Asn p.D955N ENST00000265080 NM_006909.2 955 Gac/Aac 0 +RASGRP3 UCSF GRCh37 2 33774715 33774715 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 233 26 333 0 ENST00000403687.3:c.1439G>A p.Arg480Lys p.R480K ENST00000403687 NM_001139488.1 480 aGa/aAa 0 +RASGRP4 UCSF GRCh37 19 38900712 38900712 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 17 118 0 ENST00000587738.1:c.1990C>T p.Pro664Ser p.P664S ENST00000587738 664 Cca/Tca 0 +RASSF2 UCSF GRCh37 20 4771121 4771121 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 91 14 148 0 ENST00000379400.3:c.513C>T p.Ile171= p.I171= ENST00000379400 NM_014737.2 171 atC/atT 0 +RB1CC1 UCSF GRCh37 8 53574101 53574101 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 10 68 0 ENST00000025008.5:c.1352G>A p.Arg451Lys p.R451K ENST00000025008 NM_014781.4 451 aGa/aAa 0 +RBBP7 UCSF GRCh37 X 16887659 16887659 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 61 86 0 ENST00000380084.4:c.106G>A p.Gly36Ser p.G36S ENST00000380084 NM_001198719.1 36 Ggt/Agt 0 +RBFOX1 UCSF GRCh37 16 7726800 7726800 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 31 227 0 ENST00000311745.5:c.1018G>A p.Ala340Thr p.A340T ENST00000311745 NM_145891.2 340 Gcc/Acc 0 +RBFOX2 UCSF GRCh37 22 36142030 36142030 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 8 82 0 ENST00000438146.2:c.1251G>A p.Val417= p.V417= ENST00000438146 NM_001082578.1 417 gtG/gtA 0 +RBL1 UCSF GRCh37 20 35635934 35635934 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 17 139 0 ENST00000373664.3:c.2751C>T p.Asp917= p.D917= ENST00000373664 NM_002895.3 917 gaC/gaT 0 +RBM12 UCSF GRCh37 20 34241786 34241786 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 339 82 588 0 ENST00000374114.3:c.1459G>A p.Ala487Thr p.A487T ENST00000374114 NM_001198838.1 487 Gct/Act 0 +RBM14 UCSF GRCh37 11 66393129 66393129 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 13 22 0 ENST00000310137.4:c.1782G>A p.Lys594= p.K594= ENST00000310137 NM_006328.3 594 aaG/aaA 0 +RBM15 UCSF GRCh37 1 110882844 110882844 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 25 175 0 ENST00000369784.3:c.817G>A p.Val273Ile p.V273I ENST00000369784 NM_022768.4 273 Gtc/Atc 0 +RBM15 UCSF GRCh37 1 110888949 110888949 + 3_prime_UTR_variant 3'UTR SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 11 114 0 ENST00000369784.3:c.*60G>A *20* ENST00000369784 NM_022768.4 0 +RBM15B UCSF GRCh37 3 51431474 51431474 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 20 233 0 ENST00000323686.4:c.2644G>A p.Val882Met p.V882M ENST00000323686 NM_013286.4 882 Gtg/Atg 0 +RBM19 UCSF GRCh37 12 114282513 114282513 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 32 0 ENST00000545145.2:c.2745C>T p.Thr915= p.T915= ENST00000545145 NM_001146699.1 915 acC/acT 0 +RBM20 UCSF GRCh37 10 112570210 112570210 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 12 65 0 ENST00000369519.3:c.1870G>A p.Glu624Lys p.E624K ENST00000369519 NM_001134363.1 624 Gaa/Aaa 0 +RBM45 UCSF GRCh37 2 178981094 178981094 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 22 233 0 ENST00000286070.5:c.406C>T p.Leu136= p.L136= ENST00000286070 NM_152945.2 136 Ctg/Ttg 0 +RBM47 UCSF GRCh37 4 40438596 40438596 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 448 66 693 0 ENST00000381793.2:c.1192C>T p.Leu398Phe p.L398F ENST00000381793 398 Ctc/Ttc 0 +RBMS3 UCSF GRCh37 3 29323205 29323205 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 11 91 0 ENST00000383767.2:c.33C>T p.Tyr11= p.Y11= ENST00000383767 11 taC/taT 0 +RBPJ UCSF GRCh37 4 26431661 26431661 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 33 137 0 ENST00000342295.1:c.1069G>A p.Val357Ile p.V357I ENST00000342295 NM_005349.3 357 Gta/Ata 0 +RBPJL UCSF GRCh37 20 43943147 43943147 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 4 32 0 ENST00000343694.3:c.962C>T p.Pro321Leu p.P321L ENST00000343694 NM_001281449.1 321 cCc/cTc 0 +RC3H1 UCSF GRCh37 1 173916628 173916628 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 26 161 0 ENST00000367696.2:c.2616C>T p.Asp872= p.D872= ENST00000367696 872 gaC/gaT 0 +RDBP UCSF GRCh37 6 31922509 31922509 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 479 86 601 0 ENST00000375429.3:c.565G>A p.Asp189Asn p.D189N ENST00000375429 NM_002904.5 189 Gac/Aac 0 +RDBP UCSF GRCh37 6 31922869 31922869 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 43 338 0 ENST00000375429.3:c.371C>T p.Ser124Phe p.S124F ENST00000375429 NM_002904.5 124 tCc/tTc 0 +RDX UCSF GRCh37 11 110150413 110150413 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 12 101 0 ENST00000405097.1:c.5C>T p.Pro2Leu p.P2L ENST00000405097 NM_001260492.1 2 cCg/cTg 0 +RELN UCSF GRCh37 7 103230049 103230049 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 29 176 0 ENST00000428762.1:c.4139C>T p.Ala1380Val p.A1380V ENST00000428762 NM_005045.3 1380 gCa/gTa 0 +REPIN1 UCSF GRCh37 7 150068904 150068904 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 224 26 186 0 ENST00000489432.2:c.745C>T p.Leu249= p.L249= ENST00000489432 NM_001099695.1 249 Cta/Tta 0 +RERE UCSF GRCh37 1 8422742 8422742 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 27 349 0 ENST00000337907.3:c.1902+1G>A p.X634_splice ENST00000337907 NM_012102.3 0 +RET UCSF GRCh37 10 43608383 43608383 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 6 76 0 ENST00000355710.3:c.1731C>T p.Asp577= p.D577= ENST00000355710 NM_020975.4 577 gaC/gaT 0 +RET UCSF GRCh37 10 43610025 43610025 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 426 63 627 0 ENST00000355710.3:c.1977C>T p.Cys659= p.C659= ENST00000355710 NM_020975.4 659 tgC/tgT 0 +REV3L UCSF GRCh37 6 111737541 111737541 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 16 199 0 ENST00000358835.3:c.274G>A p.Gly92Ser p.G92S ENST00000358835 92 Ggc/Agc 0 +RFC4 UCSF GRCh37 3 186512468 186512468 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 16 131 0 ENST00000392481.2:c.389C>T p.Thr130Ile p.T130I ENST00000392481 NM_181573.2 130 aCt/aTt 0 +RFNG UCSF GRCh37 17 80009379 80009379 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 3 29 0 ENST00000310496.4:c.264G>A p.Gln88= p.Q88= ENST00000310496 NM_002917.1 88 caG/caA 0 +RFTN2 UCSF GRCh37 2 198436747 198436747 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 542 78 743 0 ENST00000295049.4:c.1491G>A p.Gln497= p.Q497= ENST00000295049 NM_144629.2 497 caG/caA 0 +RFX6 UCSF GRCh37 6 117199071 117199071 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 7 72 0 ENST00000332958.2:c.336G>A p.Gln112= p.Q112= ENST00000332958 NM_173560.3 112 caG/caA 0 +RFX7 UCSF GRCh37 15 56435004 56435004 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 16 140 0 ENST00000423270.1:c.373C>T p.Pro125Ser p.P125S ENST00000423270 NM_022841.5 125 Ccc/Tcc 0 +RGS18 UCSF GRCh37 1 192153595 192153595 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 81 324 0 ENST00000367460.3:c.619C>T p.Gln207Ter p.Q207* ENST00000367460 NM_130782.2 207 Cag/Tag 0 +RHAG UCSF GRCh37 6 49587023 49587023 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 3 33 0 ENST00000371175.4:c.210C>T p.Thr70= p.T70= ENST00000371175 NM_000324.2 70 acC/acT 0 +RHOT2 UCSF GRCh37 16 718393 718393 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 71 203 0 ENST00000315082.4:c.78C>T p.Gly26= p.G26= ENST00000315082 NM_138769.2 26 ggC/ggT 0 +RHOXF1 UCSF GRCh37 X 119249374 119249374 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 13 83 0 ENST00000217999.2:c.398+1G>A p.X133_splice ENST00000217999 NM_139282.2 0 +RHPN1 UCSF GRCh37 8 144460959 144460959 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 139 356 0 ENST00000289013.6:c.553C>T p.Pro185Ser p.P185S ENST00000289013 NM_052924.2 185 Cct/Tct 0 +RICTOR UCSF GRCh37 5 38957753 38957753 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 35 322 0 ENST00000357387.3:c.2499+1G>A p.X833_splice ENST00000357387 NM_152756.3 0 +RICTOR UCSF GRCh37 5 38952427 38952427 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 281 41 397 0 ENST00000357387.3:c.2998C>T p.Leu1000= p.L1000= ENST00000357387 NM_152756.3 1000 Ctg/Ttg 0 +RIMBP2 UCSF GRCh37 12 130963546 130963546 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 7 64 0 ENST00000261655.4:c.13G>A p.Ala5Thr p.A5T ENST00000261655 NM_015347.4 5 Gct/Act 0 +RLF UCSF GRCh37 1 40661304 40661304 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 14 67 0 ENST00000372771.4:c.475G>A p.Glu159Lys p.E159K ENST00000372771 NM_012421.3 159 Gag/Aag 0 +RMI1 UCSF GRCh37 9 86617385 86617385 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 293 55 430 1 ENST00000325875.3:c.1484C>T p.Ser495Phe p.S495F ENST00000325875 NM_024945.2 495 tCt/tTt 0 +RND1 UCSF GRCh37 12 49254849 49254849 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 10 72 0 ENST00000309739.5:c.384C>T p.Asp128= p.D128= ENST00000309739 NM_014470.3 128 gaC/gaT 0 +RNF126 UCSF GRCh37 19 650255 650255 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 13 25 0 ENST00000292363.5:c.485C>T p.Thr162Ile p.T162I ENST00000292363 NM_194460.2 162 aCc/aTc 0 +RNF144A UCSF GRCh37 2 7164616 7164616 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 23 192 0 ENST00000320892.6:c.626C>T p.Ala209Val p.A209V ENST00000320892 NM_014746.3 209 gCc/gTc 0 +RNF146 UCSF GRCh37 6 127608726 127608726 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 36 268 0 ENST00000368314.1:c.968C>T p.Pro323Leu p.P323L ENST00000368314 NM_001242850.1 323 cCc/cTc 0 +RNF17 UCSF GRCh37 13 25418078 25418078 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 16 259 0 ENST00000255324.5:c.2800C>T p.Gln934Ter p.Q934* ENST00000255324 NM_031277.2 934 Cag/Tag 0 +RNF182 UCSF GRCh37 6 13977943 13977943 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 72 256 0 ENST00000488300.1:c.593C>T p.Pro198Leu p.P198L ENST00000488300 NM_152737.3 198 cCc/cTc 0 +RNF2 UCSF GRCh37 1 185067214 185067214 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 10 86 0 ENST00000367510.3:c.475G>A p.Gly159Ser p.G159S ENST00000367510 NM_007212.3 159 Ggc/Agc 0 +RNF213 UCSF GRCh37 17 78343302 78343302 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 6 64 0 ENST00000582970.1:c.12156G>A p.Arg4052= p.R4052= ENST00000582970 NM_001256071.1 4052 agG/agA 0 +RNF34 UCSF GRCh37 12 121858387 121858387 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 11 67 0 ENST00000392465.3:c.737G>A p.Gly246Glu p.G246E ENST00000392465 NM_194271.2 246 gGg/gAg 0 +RNF44 UCSF GRCh37 5 175958506 175958506 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 45 0 ENST00000274811.4:c.423G>A p.Met141Ile p.M141I ENST00000274811 NM_014901.4 141 atG/atA 0 +RNH1 UCSF GRCh37 11 498538 498538 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 21 161 0 ENST00000534797.1:c.875C>T p.Ala292Val p.A292V ENST00000534797 292 gCc/gTc 0 +RORA UCSF GRCh37 15 61521328 61521328 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 11 96 0 ENST00000335670.6:c.90G>A p.Pro30= p.P30= ENST00000335670 NM_134261.2 30 ccG/ccA 0 +RPAP1 UCSF GRCh37 15 41816446 41816446 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 7 61 0 ENST00000304330.4:c.2082C>T p.Leu694= p.L694= ENST00000304330 NM_015540.2 694 ctC/ctT 0 +RPL5 UCSF GRCh37 1 93299127 93299127 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 16 99 0 ENST00000370321.3:c.99G>A p.Arg33= p.R33= ENST00000370321 NM_000969.3 33 cgG/cgA 0 +RPL7 UCSF GRCh37 8 74204015 74204015 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 141 25 235 0 ENST00000352983.2:c.421G>A p.Ala141Thr p.A141T ENST00000352983 141 Gca/Aca 0 +RPP25 UCSF GRCh37 15 75248864 75248864 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 86 72 184 0 ENST00000322177.5:c.61G>A p.Gly21Ser p.G21S ENST00000322177 NM_017793.2 21 Ggc/Agc 0 +RPRD2 UCSF GRCh37 1 150443190 150443190 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 19 256 0 ENST00000369068.4:c.1766G>A p.Ser589Asn p.S589N ENST00000369068 NM_015203.3 589 aGc/aAc 0 +RPS23 UCSF GRCh37 5 81573621 81573621 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 242 45 335 0 ENST00000296674.8:c.55G>A p.Asp19Asn p.D19N ENST00000296674 NM_001025.4 19 Gac/Aac 0 +RPS6KA2 UCSF GRCh37 6 167275595 167275595 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 7 97 0 ENST00000503859.1:c.63+1G>A p.X21_splice ENST00000503859 NM_001006932.1 0 +RPS6KA4 UCSF GRCh37 11 64135622 64135622 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 194 30 293 0 ENST00000334205.4:c.1090C>T p.Pro364Ser p.P364S ENST00000334205 NM_003942.2 364 Ccc/Tcc 0 +RPS6KA5 UCSF GRCh37 14 91389456 91389456 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 24 274 0 ENST00000261991.3:c.702+1G>A p.X234_splice ENST00000261991 NM_004755.2 0 +RPS6KL1 UCSF GRCh37 14 75374226 75374226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 26 198 0 ENST00000555647.1:c.1451C>T p.Ser484Phe p.S484F ENST00000555647 484 tCc/tTc 0 +RPTN UCSF GRCh37 1 152127274 152127274 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 762 127 903 0 ENST00000316073.3:c.2301C>T p.Asn767= p.N767= ENST00000316073 NM_001122965.1 767 aaC/aaT 0 +RPTOR UCSF GRCh37 17 78765296 78765296 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 10 123 0 ENST00000306801.3:c.877G>A p.Asp293Asn p.D293N ENST00000306801 NM_020761.2 293 Gat/Aat 0 +RPUSD2 UCSF GRCh37 15 40861556 40861556 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 10 77 0 ENST00000315616.7:c.20G>A p.Gly7Glu p.G7E ENST00000315616 NM_152260.1 7 gGa/gAa 0 +RRAGA UCSF GRCh37 9 19049980 19049980 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 22 230 0 ENST00000380527.1:c.323C>T p.Ser108Leu p.S108L ENST00000380527 NM_006570.4 108 tCg/tTg 0 +RREB1 UCSF GRCh37 6 7231216 7231216 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 17 137 0 ENST00000379938.2:c.2884G>A p.Glu962Lys p.E962K ENST00000379938 NM_001003700.1 962 Gag/Aag 0 +RREB1 UCSF GRCh37 6 7231282 7231282 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 14 104 0 ENST00000379938.2:c.2950G>A p.Gly984Arg p.G984R ENST00000379938 NM_001003700.1 984 Ggg/Agg 0 +RRN3 UCSF GRCh37 16 15166849 15166849 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 10 118 0 ENST00000198767.6:c.1086C>T p.Cys362= p.C362= ENST00000198767 NM_018427.3 362 tgC/tgT 0 +RRP1 UCSF GRCh37 21 45217919 45217919 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 7 43 0 ENST00000497547.1:c.749C>T p.Ser250Phe p.S250F ENST00000497547 NM_003683.5 250 tCc/tTc 0 +RRP9 UCSF GRCh37 3 51968521 51968521 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 21 153 0 ENST00000232888.6:c.1227C>T p.Phe409= p.F409= ENST00000232888 NM_004704.4 409 ttC/ttT 0 +RSAD1 UCSF GRCh37 17 48557042 48557042 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 9 67 0 ENST00000258955.2:c.188C>T p.Pro63Leu p.P63L ENST00000258955 NM_018346.1 63 cCt/cTt 0 +RSF1 UCSF GRCh37 11 77394779 77394779 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 43 373 0 ENST00000308488.6:c.3041G>A p.Arg1014Lys p.R1014K ENST00000308488 1014 aGa/aAa 0 +RSPH4A UCSF GRCh37 6 116937853 116937853 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 43 135 0 ENST00000229554.5:c.67C>T p.Pro23Ser p.P23S ENST00000229554 NM_001010892.2 23 Cca/Tca 0 +RSPH6A UCSF GRCh37 19 46305384 46305384 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 258 38 398 0 ENST00000221538.3:c.1792G>A p.Asp598Asn p.D598N ENST00000221538 NM_030785.3 598 Gat/Aat 0 +RTCD1 UCSF GRCh37 1 100732140 100732140 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 17 143 0 ENST00000260563.4:c.106G>A p.Val36Met p.V36M ENST00000260563 NM_001130841.1 36 Gtg/Atg 0 +RTEL1 UCSF GRCh37 20 62292650 62292650 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 5 30 0 ENST00000508582.2:c.103-1G>A p.X35_splice ENST00000508582 0 +RTTN UCSF GRCh37 18 67857947 67857947 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 11 173 0 ENST00000255674.6:c.1016G>A p.Ser339Asn p.S339N ENST00000255674 NM_173630.3 339 aGt/aAt 0 +RUNDC1 UCSF GRCh37 17 41143722 41143722 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 200 28 290 0 ENST00000361677.1:c.1831G>A p.Asp611Asn p.D611N ENST00000361677 NM_173079.2 611 Gat/Aat 0 +RUNDC3A UCSF GRCh37 17 42386308 42386308 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 6 52 0 ENST00000426726.3:c.107+1G>A p.X36_splice ENST00000426726 NM_001144825.1 0 +RUSC2 UCSF GRCh37 9 35555506 35555506 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 55 165 0 ENST00000455600.1:c.2464C>T p.Pro822Ser p.P822S ENST00000455600 NM_001135999.1 822 Cct/Tct 0 +RXFP1 UCSF GRCh37 4 159554622 159554622 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 8 160 0 ENST00000307765.5:c.965C>T p.Ser322Leu p.S322L ENST00000307765 NM_001253728.1 322 tCa/tTa 0 +RXRA UCSF GRCh37 9 137320968 137320968 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 33 284 0 ENST00000481739.1:c.925C>T p.Leu309Phe p.L309F ENST00000481739 NM_002957.4 309 Ctc/Ttc 0 +RXRA UCSF GRCh37 9 137321053 137321053 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 60 159 0 ENST00000481739.1:c.1010C>T p.Ala337Val p.A337V ENST00000481739 NM_002957.4 337 gCc/gTc 0 +RYBP UCSF GRCh37 3 72427537 72427537 + stop_retained_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 16 211 0 ENST00000477973.2:c.951G>A p.Ter318= p.*318= ENST00000477973 NM_012234.5 318 tGa/tAa 0 +RYR1 UCSF GRCh37 19 38931413 38931413 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 47 0 ENST00000359596.3:c.74C>T p.Ala25Val p.A25V ENST00000359596 25 gCt/gTt 0 +RYR1 UCSF GRCh37 19 38985127 38985127 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 14 91 0 ENST00000359596.3:c.6410C>T p.Ala2137Val p.A2137V ENST00000359596 2137 gCc/gTc 0 +RYR1 UCSF GRCh37 19 38993213 38993213 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 237 48 333 0 ENST00000359596.3:c.7681C>T p.Leu2561Phe p.L2561F ENST00000359596 2561 Ctc/Ttc 0 +RYR1 UCSF GRCh37 19 38985070 38985070 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 7 39 0 ENST00000359596.3:c.6353G>A p.Arg2118Gln p.R2118Q ENST00000359596 2118 cGg/cAg 0 +RYR1 UCSF GRCh37 19 38964070 38964070 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 10 111 0 ENST00000359596.3:c.3819C>T p.His1273= p.H1273= ENST00000359596 1273 caC/caT 0 +RYR3 UCSF GRCh37 15 34040384 34040384 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 3 58 0 ENST00000389232.4:c.8059G>A p.Glu2687Lys p.E2687K ENST00000389232 NM_001036.3 2687 Gag/Aag 0 +S100PBP UCSF GRCh37 1 33292420 33292420 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 22 122 0 ENST00000373475.5:c.720G>A p.Arg240= p.R240= ENST00000373475 NM_022753.3 240 cgG/cgA 0 +S1PR1 UCSF GRCh37 1 101705160 101705160 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 446 51 564 0 ENST00000305352.6:c.620C>T p.Thr207Ile p.T207I ENST00000305352 NM_001400.4 207 aCc/aTc 0 +S1PR1 UCSF GRCh37 1 101705464 101705464 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 282 53 366 0 ENST00000305352.6:c.924C>T p.Pro308= p.P308= ENST00000305352 NM_001400.4 308 ccC/ccT 0 +SAG UCSF GRCh37 2 234237205 234237205 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 16 148 0 ENST00000409110.1:c.594G>A p.Trp198Ter p.W198* ENST00000409110 NM_000541.4 198 tgG/tgA 0 +SAMD15 UCSF GRCh37 14 77844770 77844770 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 15 154 0 ENST00000216471.4:c.1009C>T p.Pro337Ser p.P337S ENST00000216471 NM_001010860.1 337 Cct/Tct 0 +SAMD9 UCSF GRCh37 7 92730948 92730948 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 293 53 505 0 ENST00000379958.2:c.4463G>A p.Arg1488Lys p.R1488K ENST00000379958 NM_017654.3 1488 aGa/aAa 0 +SARDH UCSF GRCh37 9 136577769 136577769 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 10 77 0 ENST00000371872.4:c.1300G>A p.Glu434Lys p.E434K ENST00000371872 NM_007101.3 434 Gag/Aag 0 +SARDH UCSF GRCh37 9 136568071 136568071 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 9 54 0 ENST00000371872.4:c.1635G>A p.Glu545= p.E545= ENST00000371872 NM_007101.3 545 gaG/gaA 0 +SARM1 UCSF GRCh37 17 26715552 26715552 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 12 66 0 ENST00000457710.3:c.1815G>A p.Val605= p.V605= ENST00000457710 NM_015077.3 605 gtG/gtA 0 +SARS UCSF GRCh37 1 109779146 109779146 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 7 80 0 ENST00000234677.2:c.1233G>A p.Gly411= p.G411= ENST00000234677 NM_006513.3 411 ggG/ggA 0 +SART3 UCSF GRCh37 12 108931935 108931935 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 15 156 0 ENST00000228284.3:c.1107C>T p.Asn369= p.N369= ENST00000228284 NM_014706.3 369 aaC/aaT 0 +SBF2 UCSF GRCh37 11 9812175 9812175 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 16 155 0 ENST00000256190.8:c.4626G>A p.Trp1542Ter p.W1542* ENST00000256190 NM_030962.3 1542 tgG/tgA 0 +SCAF1 UCSF GRCh37 19 50154164 50154164 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 123 63 208 0 ENST00000360565.3:c.518G>A p.Arg173His p.R173H ENST00000360565 NM_021228.2 173 cGt/cAt 0 +SCAF1 UCSF GRCh37 19 50158012 50158012 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 239 34 370 0 ENST00000360565.3:c.3503G>A p.Gly1168Asp p.G1168D ENST00000360565 NM_021228.2 1168 gGc/gAc 0 +SCAF1 UCSF GRCh37 19 50157655 50157655 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 11 114 0 ENST00000360565.3:c.3366G>A p.Ala1122= p.A1122= ENST00000360565 NM_021228.2 1122 gcG/gcA 0 +SCAND3 UCSF GRCh37 6 28542726 28542726 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 16 213 0 ENST00000452236.2:c.1756C>T p.Pro586Ser p.P586S ENST00000452236 NM_052923.1 586 Cct/Tct 0 +SCIN UCSF GRCh37 7 12617790 12617790 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 12 105 0 ENST00000297029.5:c.301G>A p.Gly101Arg p.G101R ENST00000297029 NM_001112706.2 101 Gga/Aga 0 +SCN10A UCSF GRCh37 3 38783835 38783835 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 9 92 0 ENST00000449082.2:c.2053G>A p.Glu685Lys p.E685K ENST00000449082 NM_006514.2 685 Gag/Aag 0 +SCN1A UCSF GRCh37 2 166930062 166930062 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 32 270 0 ENST00000303395.4:c.70G>A p.Ala24Thr p.A24T ENST00000303395 24 Gct/Act 0 +SCN2A UCSF GRCh37 2 166152547 166152547 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 12 86 0 ENST00000357398.3:c.214G>A p.Glu72Lys p.E72K ENST00000357398 72 Gag/Aag 0 +SCN5A UCSF GRCh37 3 38592472 38592472 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 87 255 0 ENST00000413689.1:c.5391C>T p.Ile1797= p.I1797= ENST00000413689 NM_001160160.1 1797 atC/atT 0 +SCNN1B UCSF GRCh37 16 23364211 23364211 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 252 35 376 0 ENST00000343070.2:c.401C>T p.Ala134Val p.A134V ENST00000343070 NM_000336.2 134 gCc/gTc 0 +SCNN1D UCSF GRCh37 1 1226800 1226800 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 26 71 0 ENST00000379116.5:c.2219G>A p.Ser740Asn p.S740N ENST00000379116 NM_001130413.3 740 aGc/aAc 0 +SCNN1G UCSF GRCh37 16 23226446 23226446 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 36 109 0 ENST00000300061.2:c.1606G>A p.Gly536Ser p.G536S ENST00000300061 NM_001039.3 536 Ggc/Agc 0 +SCP2 UCSF GRCh37 1 53446172 53446172 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 27 254 0 ENST00000371514.3:c.930C>T p.Thr310= p.T310= ENST00000371514 NM_002979.4 310 acC/acT 0 +SCRN1 UCSF GRCh37 7 29983761 29983761 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 239 30 227 0 ENST00000434476.2:c.436G>A p.Ala146Thr p.A146T ENST00000434476 NM_001145514.1 146 Gcc/Acc 0 +SCYL1 UCSF GRCh37 11 65293787 65293787 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 4 19 0 ENST00000270176.5:c.568G>A p.Ala190Thr p.A190T ENST00000270176 NM_020680.3 190 Gct/Act 0 +SDCCAG3 UCSF GRCh37 9 139301920 139301920 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 4 33 0 ENST00000357365.3:c.496G>A p.Asp166Asn p.D166N ENST00000357365 NM_001039707.1 166 Gat/Aat 0 +SDF2L1 UCSF GRCh37 22 21997337 21997337 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 10 31 0 ENST00000248958.4:c.374C>T p.Ser125Phe p.S125F ENST00000248958 NM_022044.2 125 tCc/tTc 0 +SDK1 UCSF GRCh37 7 4249791 4249791 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 14 96 0 ENST00000404826.2:c.5536C>T p.Gln1846Ter p.Q1846* ENST00000404826 NM_152744.3 1846 Caa/Taa 0 +SEC14L1 UCSF GRCh37 17 75202374 75202374 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 4 22 0 ENST00000392476.2:c.1233G>A p.Val411= p.V411= ENST00000392476 NM_001204408.1 411 gtG/gtA 0 +SEC16B UCSF GRCh37 1 177901632 177901632 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 4 16 0 ENST00000308284.6:c.3005G>A p.Gly1002Glu p.G1002E ENST00000308284 NM_033127.2 1002 gGa/gAa 0 +SEC31B UCSF GRCh37 10 102266174 102266174 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 39 172 0 ENST00000370345.3:c.786G>A p.Gly262= p.G262= ENST00000370345 NM_015490.3 262 ggG/ggA 0 +SEC61A1 UCSF GRCh37 3 127785845 127785845 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 281 43 433 0 ENST00000243253.3:c.826T>C p.Tyr276His p.Y276H ENST00000243253 NM_013336.3 276 Tac/Cac 0 +SEC63 UCSF GRCh37 6 108243022 108243022 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 43 332 0 ENST00000369002.4:c.431G>A p.Arg144Lys p.R144K ENST00000369002 NM_007214.4 144 aGg/aAg 0 +SEC63 UCSF GRCh37 6 108215043 108215043 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 187 30 395 0 ENST00000369002.4:c.1499G>A p.Gly500Glu p.G500E ENST00000369002 NM_007214.4 500 gGg/gAg 0 +SECISBP2L UCSF GRCh37 15 49311736 49311736 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 8 79 0 ENST00000559471.1:c.1049G>A p.Cys350Tyr p.C350Y ENST00000559471 NM_001193489.1 350 tGc/tAc 0 +SEL1L UCSF GRCh37 14 81993227 81993227 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 35 261 0 ENST00000336735.4:c.190G>A p.Glu64Lys p.E64K ENST00000336735 NM_005065.5 64 Gaa/Aaa 0 +SEL1L2 UCSF GRCh37 20 13867010 13867010 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 16 192 0 ENST00000378072.5:c.824C>T p.Ser275Phe p.S275F ENST00000378072 NM_001271539.1 275 tCt/tTt 0 +SELENBP1 UCSF GRCh37 1 151341631 151341631 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 8 38 0 ENST00000368868.5:c.209A>G p.Asp70Gly p.D70G ENST00000368868 NM_003944.3 70 gAc/gGc 0 +SELT UCSF GRCh37 3 150321233 150321233 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 71 0 ENST00000471696.1:c.84C>T p.Ser28= p.S28= ENST00000471696 NM_016275.3 28 agC/agT 0 +SEMA3E UCSF GRCh37 7 83036460 83036460 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 13 147 0 ENST00000307792.3:c.766G>A p.Glu256Lys p.E256K ENST00000307792 NM_012431.2 256 Gaa/Aaa 0 +SEMA3F UCSF GRCh37 3 50220407 50220407 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 18 150 0 ENST00000002829.3:c.974C>T p.Ser325Phe p.S325F ENST00000002829 NM_004186.3 325 tCt/tTt 0 +SEMA4C UCSF GRCh37 2 97530011 97530011 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 10 80 0 ENST00000305476.5:c.1071C>T p.Arg357= p.R357= ENST00000305476 NM_017789.4 357 cgC/cgT 0 +SEMA4D UCSF GRCh37 9 91994525 91994525 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 11 138 0 ENST00000450295.1:c.1683C>T p.Tyr561= p.Y561= ENST00000450295 561 taC/taT 0 +SEMA5B UCSF GRCh37 3 122631167 122631167 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 13 90 0 ENST00000451055.2:c.2910G>A p.Trp970Ter p.W970* ENST00000451055 NM_001256347.1 970 tgG/tgA 0 +SEMA6A UCSF GRCh37 5 115782924 115782924 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 20 192 0 ENST00000343348.6:c.2478G>A p.Gln826= p.Q826= ENST00000343348 NM_020796.3 826 caG/caA 0 +SENP7 UCSF GRCh37 3 101066866 101066866 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 45 189 0 ENST00000394095.2:c.1687G>A p.Asp563Asn p.D563N ENST00000394095 NM_020654.3 563 Gat/Aat 0 +SENP7 UCSF GRCh37 3 101049182 101049182 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 207 35 379 0 ENST00000394095.2:c.2747C>T p.Ser916Phe p.S916F ENST00000394095 NM_020654.3 916 tCc/tTc 0 +SEPT9 UCSF GRCh37 17 75488714 75488714 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 41 144 0 ENST00000427177.1:c.1392C>T p.Asp464= p.D464= ENST00000427177 NM_001113491.1 464 gaC/gaT 0 +SERPINA10 UCSF GRCh37 14 94752585 94752585 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 29 255 0 ENST00000393096.1:c.1003G>A p.Val335Ile p.V335I ENST00000393096 NM_016186.2 335 Gtt/Att 0 +SERPINA11 UCSF GRCh37 14 94914700 94914700 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 15 183 0 ENST00000334708.3:c.412G>A p.Gly138Arg p.G138R ENST00000334708 NM_001080451.1 138 Gga/Aga 0 +SERPINA11 UCSF GRCh37 14 94914822 94914822 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 15 143 0 ENST00000334708.3:c.290C>T p.Ala97Val p.A97V ENST00000334708 NM_001080451.1 97 gCt/gTt 0 +SERPINF2 UCSF GRCh37 17 1649012 1649012 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 8 78 0 ENST00000324015.3:c.176G>A p.Gly59Asp p.G59D ENST00000324015 NM_000934.3 59 gGc/gAc 0 +SERTAD1 UCSF GRCh37 19 40929053 40929053 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 16 106 0 ENST00000357949.4:c.401C>T p.Pro134Leu p.P134L ENST00000357949 NM_013376.3 134 cCc/cTc 0 +SERTAD2 UCSF GRCh37 2 64863823 64863823 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 10 121 1 ENST00000313349.3:c.183G>A p.Lys61= p.K61= ENST00000313349 NM_014755.2 61 aaG/aaA 0 +SESN3 UCSF GRCh37 11 94910922 94910922 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 8 154 0 ENST00000536441.1:c.1208G>A p.Arg403Lys p.R403K ENST00000536441 NM_144665.3 403 aGa/aAa 0 +SETBP1 UCSF GRCh37 18 42530356 42530356 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 317 55 437 0 ENST00000282030.5:c.1051G>A p.Asp351Asn p.D351N ENST00000282030 NM_015559.2 351 Gac/Aac 0 +SETD8 UCSF GRCh37 12 123880969 123880969 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 14 110 0 ENST00000330479.4:c.587C>T p.Ala196Val p.A196V ENST00000330479 NM_020382.3 196 gCc/gTc 0 +SETDB2 UCSF GRCh37 13 50050655 50050655 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 7 109 0 ENST00000317257.8:c.385G>A p.Val129Ile p.V129I ENST00000317257 NM_031915.2 129 Gta/Ata 0 +SETX UCSF GRCh37 9 135140211 135140211 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 22 206 0 ENST00000224140.5:c.7449G>A p.Gly2483= p.G2483= ENST00000224140 NM_015046.5 2483 ggG/ggA 0 +SEZ6L2 UCSF GRCh37 16 29899902 29899902 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 16 106 0 ENST00000308713.5:c.998G>A p.Gly333Asp p.G333D ENST00000308713 NM_001114099.2 333 gGc/gAc 0 +SF3A1 UCSF GRCh37 22 30749022 30749022 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 16 145 0 ENST00000215793.8:c.103C>T p.Pro35Ser p.P35S ENST00000215793 NM_005877.4 35 Cct/Tct 0 +SF3B2 UCSF GRCh37 11 65825560 65825560 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 5 57 0 ENST00000322535.6:c.813G>A p.Gln271= p.Q271= ENST00000322535 NM_006842.2 271 caG/caA 0 +SFI1 UCSF GRCh37 22 31946261 31946261 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 10 73 0 ENST00000400288.2:c.471G>A p.Met157Ile p.M157I ENST00000400288 NM_001007467.2 157 atG/atA 0 +SFI1 UCSF GRCh37 22 32000897 32000897 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 14 32 0 ENST00000400288.2:c.2020G>A p.Ala674Thr p.A674T ENST00000400288 NM_001007467.2 674 Gcc/Acc 0 +SFI1 UCSF GRCh37 22 31974436 31974436 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 7 51 0 ENST00000400288.2:c.1153C>T p.Leu385= p.L385= ENST00000400288 NM_001007467.2 385 Ctg/Ttg 0 +SFMBT1 UCSF GRCh37 3 52955848 52955848 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 16 143 0 ENST00000394752.3:c.1132-1G>A p.X378_splice ENST00000394752 NM_016329.3 0 +SFSWAP UCSF GRCh37 12 132195854 132195854 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 21 152 0 ENST00000541286.1:c.80G>A p.Gly27Asp p.G27D ENST00000541286 NM_001261411.1 27 gGc/gAc 0 +SFTPB UCSF GRCh37 2 85895263 85895263 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 8 25 0 ENST00000393822.3:c.80C>T p.Pro27Leu p.P27L ENST00000393822 27 cCc/cTc 0 +SFTPB UCSF GRCh37 2 85894253 85894253 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 9 110 0 ENST00000393822.3:c.279G>A p.Lys93= p.K93= ENST00000393822 93 aaG/aaA 0 +SGCG UCSF GRCh37 13 23777883 23777883 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 11 116 0 ENST00000218867.3:c.50G>A p.Arg17Lys p.R17K ENST00000218867 NM_000231.2 17 aGg/aAg 0 +SGK223 UCSF GRCh37 8 8185591 8185591 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 20 107 0 ENST00000520004.1:c.2701G>A p.Gly901Ser p.G901S ENST00000520004 901 Ggc/Agc 0 +SGSM2 UCSF GRCh37 17 2275523 2275523 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 16 83 0 ENST00000268989.3:c.1617G>A p.Gln539= p.Q539= ENST00000268989 NM_014853.2 539 caG/caA 0 +SGSM2 UCSF GRCh37 17 2276363 2276363 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 12 95 0 ENST00000268989.3:c.1905G>A p.Lys635= p.K635= ENST00000268989 NM_014853.2 635 aaG/aaA 0 +SH2B1 UCSF GRCh37 16 28880534 28880534 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 84 248 0 ENST00000322610.8:c.1139G>A p.Cys380Tyr p.C380Y ENST00000322610 380 tGc/tAc 0 +SH2D1B UCSF GRCh37 1 162368778 162368778 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 24 198 0 ENST00000367929.2:c.298C>T p.Pro100Ser p.P100S ENST00000367929 NM_053282.4 100 Cca/Tca 0 +SH2D7 UCSF GRCh37 15 78393664 78393664 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 16 156 0 ENST00000328828.5:c.1069G>A p.Glu357Lys p.E357K ENST00000328828 NM_001101404.1 357 Gaa/Aaa 0 +SH3BGR UCSF GRCh37 21 40883652 40883652 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 10 35 0 ENST00000333634.4:c.670G>A p.Glu224Lys p.E224K ENST00000333634 NM_007341.2 224 Gag/Aag 0 +SHANK1 UCSF GRCh37 19 51170655 51170655 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 13 111 0 ENST00000293441.1:c.4562C>T p.Pro1521Leu p.P1521L ENST00000293441 NM_016148.2 1521 cCc/cTc 0 +SHANK1 UCSF GRCh37 19 51165271 51165271 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 321 38 488 0 ENST00000293441.1:c.6437G>A p.Gly2146Asp p.G2146D ENST00000293441 NM_016148.2 2146 gGc/gAc 0 +SHANK3 UCSF GRCh37 22 51154125 51154125 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 14 187 0 ENST00000262795.3:c.2342G>A p.Gly781Asp p.G781D ENST00000262795 NM_033517.1 781 gGc/gAc 0 +SHMT2 UCSF GRCh37 12 57625625 57625625 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 712 152 252 0 ENST00000328923.3:c.441C>T p.Asn147= p.N147= ENST00000328923 NM_005412.5 147 aaC/aaT 0 +SHROOM2 UCSF GRCh37 X 9900536 9900536 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 15 60 0 ENST00000380913.3:c.3213G>A p.Glu1071= p.E1071= ENST00000380913 NM_001649.2 1071 gaG/gaA 0 +SIGIRR UCSF GRCh37 11 406357 406357 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 15 124 0 ENST00000431843.2:c.1061G>A p.Gly354Asp p.G354D ENST00000431843 NM_001135054.1 354 gGc/gAc 0 +SIGLEC1 UCSF GRCh37 20 3670327 3670327 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 13 108 0 ENST00000344754.4:c.4917C>T p.Phe1639= p.F1639= ENST00000344754 NM_023068.3 1639 ttC/ttT 0 +SIGLEC1 UCSF GRCh37 20 3678704 3678704 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 12 54 0 ENST00000344754.4:c.1863C>T p.Leu621= p.L621= ENST00000344754 NM_023068.3 621 ctC/ctT 0 +SIGLEC10 UCSF GRCh37 19 51914392 51914392 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 207 44 364 0 ENST00000356298.5:c.2055G>A p.Lys685= p.K685= ENST00000356298 NM_033130.4 685 aaG/aaA 0 +SIK3 UCSF GRCh37 11 116741100 116741100 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 5 60 0 ENST00000292055.4:c.1581C>T p.Thr527= p.T527= ENST00000292055 NM_025164.3 527 acC/acT 0 +SIPA1L1 UCSF GRCh37 14 72055812 72055812 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 34 121 0 ENST00000555818.1:c.1223A>G p.Asn408Ser p.N408S ENST00000555818 NM_015556.1 408 aAt/aGt 0 +SIPA1L3 UCSF GRCh37 19 38643479 38643479 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 18 189 0 ENST00000222345.6:c.3534-1G>A p.X1178_splice ENST00000222345 NM_015073.1 0 +SIRT2 UCSF GRCh37 19 39384465 39384465 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 14 120 0 ENST00000249396.7:c.106G>A p.Ala36Thr p.A36T ENST00000249396 NM_012237.3 36 Gca/Aca 0 +SIRT6 UCSF GRCh37 19 4174726 4174726 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 8 48 0 ENST00000337491.2:c.956C>T p.Pro319Leu p.P319L ENST00000337491 NM_016539.2 319 cCc/cTc 0 +SIRT7 UCSF GRCh37 17 79870343 79870343 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 279 49 377 0 ENST00000328666.6:c.1152C>T p.Gly384= p.G384= ENST00000328666 NM_016538.2 384 ggC/ggT 0 +SIX5 UCSF GRCh37 19 46268871 46268871 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 23 237 0 ENST00000317578.6:c.2108G>A p.Gly703Glu p.G703E ENST00000317578 NM_175875.4 703 gGg/gAg 0 +SKI UCSF GRCh37 1 2160727 2160727 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 20 169 0 ENST00000378536.4:c.522C>T p.Cys174= p.C174= ENST00000378536 NM_003036.3 174 tgC/tgT 0 +SKI UCSF GRCh37 1 2235787 2235787 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 28 238 0 ENST00000378536.4:c.1530C>T p.Ala510= p.A510= ENST00000378536 NM_003036.3 510 gcC/gcT 0 +SKOR1 UCSF GRCh37 15 68121556 68121556 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 5 27 0 ENST00000341418.5:c.2065G>A p.Ala689Thr p.A689T ENST00000341418 NM_001258024.1 689 Gcg/Acg 0 +SLC12A5 UCSF GRCh37 20 44669993 44669993 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 10 101 0 ENST00000454036.2:c.949C>T p.Leu317= p.L317= ENST00000454036 NM_001134771.1 317 Ctg/Ttg 0 +SLC12A8 UCSF GRCh37 3 124930185 124930185 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 16 165 0 ENST00000393469.4:c.9G>A p.Gln3= p.Q3= ENST00000393469 NM_001195483.1 3 caG/caA 0 +SLC13A3 UCSF GRCh37 20 45188771 45188771 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 12 62 0 ENST00000279027.4:c.1699G>A p.Ala567Thr p.A567T ENST00000279027 NM_001193342.1 567 Gca/Aca 0 +SLC14A2 UCSF GRCh37 18 43252921 43252921 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 371 61 548 0 ENST00000255226.6:c.2286G>A p.Trp762Ter p.W762* ENST00000255226 NM_007163.3 762 tgG/tgA 0 +SLC16A10 UCSF GRCh37 6 111409271 111409271 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 336 40 459 0 ENST00000368851.5:c.316G>A p.Asp106Asn p.D106N ENST00000368851 NM_018593.4 106 Gac/Aac 0 +SLC16A6 UCSF GRCh37 17 66267099 66267099 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 753 120 887 0 ENST00000327268.4:c.1202G>A p.Gly401Glu p.G401E ENST00000327268 NM_001174166.1 401 gGg/gAg 0 +SLC16A8 UCSF GRCh37 22 38477584 38477584 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 13 3 19 0 ENST00000320521.5:c.461C>T p.Pro154Leu p.P154L ENST00000320521 NM_013356.2 154 cCc/cTc 0 +SLC16A9 UCSF GRCh37 10 61413468 61413468 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 27 268 0 ENST00000395348.3:c.1316C>T p.Ala439Val p.A439V ENST00000395348 NM_194298.2 439 gCt/gTt 0 +SLC19A3 UCSF GRCh37 2 228564226 228564226 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 7 120 0 ENST00000258403.3:c.205C>T p.Pro69Ser p.P69S ENST00000258403 NM_025243.3 69 Cct/Tct 0 +SLC1A2 UCSF GRCh37 11 35338955 35338955 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 7 69 0 ENST00000278379.3:c.126G>A p.Gly42= p.G42= ENST00000278379 NM_004171.3 42 ggG/ggA 0 +SLC22A10 UCSF GRCh37 11 63065069 63065069 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 41 157 0 ENST00000332793.6:c.700G>A p.Val234Ile p.V234I ENST00000332793 NM_001039752.3 234 Gta/Ata 0 +SLC22A8 UCSF GRCh37 11 62762159 62762159 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 116 21 199 0 ENST00000336232.2:c.1071C>T p.Ile357= p.I357= ENST00000336232 NM_001184736.1 357 atC/atT 0 +SLC25A17 UCSF GRCh37 22 41173090 41173090 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 12 62 0 ENST00000435456.2:c.647C>T p.Ala216Val p.A216V ENST00000435456 NM_006358.2 216 gCc/gTc 0 +SLC25A18 UCSF GRCh37 22 18070052 18070052 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 6 38 0 ENST00000327451.6:c.560G>A p.Gly187Asp p.G187D ENST00000327451 NM_031481.1 187 gGt/gAt 0 +SLC25A25 UCSF GRCh37 9 130866028 130866028 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 11 78 0 ENST00000373068.2:c.657G>A p.Met219Ile p.M219I ENST00000373068 NM_001006641.3 219 atG/atA 0 +SLC25A31 UCSF GRCh37 4 128665894 128665894 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 20 247 0 ENST00000281154.4:c.300C>T p.Asn100= p.N100= ENST00000281154 NM_031291.2 100 aaC/aaT 0 +SLC25A33 UCSF GRCh37 1 9613713 9613713 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 16 129 0 ENST00000302692.6:c.86C>T p.Thr29Ile p.T29I ENST00000302692 NM_032315.2 29 aCt/aTt 0 +SLC25A42 UCSF GRCh37 19 19221405 19221405 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 12 56 0 ENST00000318596.7:c.677C>T p.Pro226Leu p.P226L ENST00000318596 NM_178526.4 226 cCc/cTc 0 +SLC26A10 UCSF GRCh37 12 58015596 58015596 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 668 99 174 0 ENST00000320442.4:c.679C>T p.Pro227Ser p.P227S ENST00000320442 NM_133489.2 227 Ccc/Tcc 0 +SLC26A2 UCSF GRCh37 5 149357587 149357587 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 132 65 231 0 ENST00000286298.4:c.372C>T p.Pro124= p.P124= ENST00000286298 NM_000112.3 124 ccC/ccT 0 +SLC26A3 UCSF GRCh37 7 107415274 107415274 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 196 32 301 0 ENST00000340010.5:c.1721C>T p.Ala574Val p.A574V ENST00000340010 NM_000111.2 574 gCt/gTt 0 +SLC26A8 UCSF GRCh37 6 35923186 35923186 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 28 269 0 ENST00000490799.1:c.1975G>A p.Asp659Asn p.D659N ENST00000490799 NM_052961.3 659 Gac/Aac 0 +SLC27A1 UCSF GRCh37 19 17615328 17615328 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 21 188 0 ENST00000252595.7:c.1848C>T p.Asp616= p.D616= ENST00000252595 NM_198580.1 616 gaC/gaT 0 +SLC27A3 UCSF GRCh37 1 153747976 153747976 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 24 213 0 ENST00000368661.3:c.144G>A p.Met48Ile p.M48I ENST00000368661 NM_024330.1 48 atG/atA 0 +SLC27A4 UCSF GRCh37 9 131105537 131105537 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 7 50 0 ENST00000300456.4:c.126C>T p.Ile42= p.I42= ENST00000300456 NM_005094.3 42 atC/atT 0 +SLC27A5 UCSF GRCh37 19 59010240 59010240 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 62 165 1 ENST00000263093.2:c.1808C>T p.Pro603Leu p.P603L ENST00000263093 NM_012254.2 603 cCc/cTc 0 +SLC2A13 UCSF GRCh37 12 40258622 40258622 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 17 237 0 ENST00000280871.4:c.1261C>T p.Arg421Cys p.R421C ENST00000280871 NM_052885.3 421 Cgc/Tgc 0 +SLC2A8 UCSF GRCh37 9 130165022 130165022 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 55 0 ENST00000373371.3:c.713G>A p.Gly238Glu p.G238E ENST00000373371 NM_014580.4 238 gGg/gAg 0 +SLC34A1 UCSF GRCh37 5 176823753 176823753 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 23 138 0 ENST00000324417.5:c.1194C>T p.Thr398= p.T398= ENST00000324417 NM_003052.4 398 acC/acT 0 +SLC35E1 UCSF GRCh37 19 16664598 16664598 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 31 269 0 ENST00000595753.1:c.1125C>T p.Pro375= p.P375= ENST00000595753 NM_024881.4 375 ccC/ccT 0 +SLC37A1 UCSF GRCh37 21 43967234 43967234 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 270 45 353 0 ENST00000352133.2:c.752C>T p.Ser251Phe p.S251F ENST00000352133 251 tCc/tTc 0 +SLC38A5 UCSF GRCh37 X 48324630 48324630 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 17 40 0 ENST00000376876.3:c.399G>A p.Leu133= p.L133= ENST00000376876 133 ctG/ctA 0 +SLC45A3 UCSF GRCh37 1 205631136 205631136 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 7 35 0 ENST00000367145.3:c.1077G>A p.Val359= p.V359= ENST00000367145 NM_033102.2 359 gtG/gtA 0 +SLC46A2 UCSF GRCh37 9 115649617 115649617 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 15 148 0 ENST00000374228.4:c.1206C>T p.Ser402= p.S402= ENST00000374228 NM_033051.3 402 tcC/tcT 0 +SLC4A11 UCSF GRCh37 20 3211578 3211578 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 22 173 0 ENST00000380059.3:c.1297+1G>A p.X433_splice ENST00000380059 NM_001174090.1 0 +SLC4A3 UCSF GRCh37 2 220498145 220498145 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 5 72 0 ENST00000373762.3:c.1508C>T p.Ala503Val p.A503V ENST00000373762 NM_005070.3 503 gCc/gTc 0 +SLC4A3 UCSF GRCh37 2 220502411 220502411 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 268 47 392 0 ENST00000373762.3:c.2725G>A p.Gly909Ser p.G909S ENST00000373762 NM_005070.3 909 Ggc/Agc 0 +SLC4A4 UCSF GRCh37 4 72413408 72413408 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 16 186 0 ENST00000425175.1:c.2665C>T p.Leu889= p.L889= ENST00000425175 NM_001134742.1 889 Ctg/Ttg 0 +SLC5A12 UCSF GRCh37 11 26743097 26743097 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 27 195 0 ENST00000396005.3:c.165G>A p.Leu55= p.L55= ENST00000396005 NM_178498.3 55 ttG/ttA 0 +SLC5A4 UCSF GRCh37 22 32628991 32628991 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 13 68 0 ENST00000266086.4:c.916G>A p.Asp306Asn p.D306N ENST00000266086 NM_014227.2 306 Gac/Aac 0 +SLC6A11 UCSF GRCh37 3 10861192 10861192 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 168 23 241 0 ENST00000254488.2:c.299G>A p.Gly100Glu p.G100E ENST00000254488 NM_014229.1 100 gGa/gAa 0 +SLC6A19 UCSF GRCh37 5 1208922 1208922 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 5 51 0 ENST00000304460.10:c.264G>A p.Leu88= p.L88= ENST00000304460 NM_001003841.2 88 ctG/ctA 0 +SLC6A4 UCSF GRCh37 17 28542628 28542628 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 24 239 0 ENST00000401766.2:c.1076+1G>A p.X359_splice ENST00000401766 0 +SLC7A14 UCSF GRCh37 3 170198521 170198521 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 207 34 293 0 ENST00000231706.5:c.1550C>T p.Thr517Ile p.T517I ENST00000231706 NM_020949.2 517 aCc/aTc 0 +SLC9A3 UCSF GRCh37 5 482251 482251 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 11 97 0 ENST00000264938.3:c.1378G>A p.Val460Met p.V460M ENST00000264938 NM_004174.2 460 Gtg/Atg 0 +SLC9A3R2 UCSF GRCh37 16 2086443 2086443 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 32 187 0 ENST00000424542.2:c.533C>T p.Ser178Phe p.S178F ENST00000424542 NM_001130012.2 178 tCt/tTt 0 +SLFN11 UCSF GRCh37 17 33689953 33689953 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 283 57 483 0 ENST00000394566.1:c.874C>T p.Pro292Ser p.P292S ENST00000394566 NM_001104587.1 292 Ccg/Tcg 0 +SLITRK2 UCSF GRCh37 X 144905964 144905964 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 49 200 0 ENST00000370490.1:c.2021C>T p.Thr674Ile p.T674I ENST00000370490 674 aCt/aTt 0 +SLITRK3 UCSF GRCh37 3 164906241 164906241 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 185 27 266 0 ENST00000475390.1:c.2378G>A p.Gly793Glu p.G793E ENST00000475390 793 gGa/gAa 0 +SLMAP UCSF GRCh37 3 57843847 57843847 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 13 193 0 ENST00000295951.3:c.648G>A p.Arg216= p.R216= ENST00000295951 216 cgG/cgA 0 +SMAD9 UCSF GRCh37 13 37441475 37441475 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 9 90 0 ENST00000379826.4:c.716C>T p.Thr239Ile p.T239I ENST00000379826 NM_001127217.2 239 aCc/aTc 0 +SMARCA4 UCSF GRCh37 19 11132499 11132499 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 19 94 0 ENST00000344626.4:c.2715C>T p.Arg905= p.R905= ENST00000344626 NM_003072.3 905 cgC/cgT 0 +SMARCC2 UCSF GRCh37 12 56575805 56575805 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 21 188 0 ENST00000267064.4:c.691C>T p.Pro231Ser p.P231S ENST00000267064 NM_003075.3 231 Cct/Tct 0 +SMARCD2 UCSF GRCh37 17 61914339 61914339 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 20 145 0 ENST00000448276.2:c.510C>T p.Asp170= p.D170= ENST00000448276 NM_001098426.1 170 gaC/gaT 0 +SMCR7 UCSF GRCh37 17 18167100 18167100 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 8 42 0 ENST00000395706.2:c.420G>A p.Glu140= p.E140= ENST00000395706 NM_148886.1 140 gaG/gaA 0 +SMCR8 UCSF GRCh37 17 18221380 18221380 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 316 60 443 0 ENST00000406438.3:c.2277C>T p.Cys759= p.C759= ENST00000406438 NM_144775.2 759 tgC/tgT 0 +SMG6 UCSF GRCh37 17 1989101 1989101 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 52 22 95 0 ENST00000263073.6:c.3452G>A p.Gly1151Glu p.G1151E ENST00000263073 NM_017575.4 1151 gGa/gAa 0 +SMG8 UCSF GRCh37 17 57288108 57288108 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 500 77 697 1 ENST00000543872.2:c.696G>A p.Gly232= p.G232= ENST00000543872 232 ggG/ggA 0 +SMOC2 UCSF GRCh37 6 168949859 168949859 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 8 90 0 ENST00000354536.5:c.646C>T p.Gln216Ter p.Q216* ENST00000354536 NM_022138.2 216 Cag/Tag 0 +SMTN UCSF GRCh37 22 31483980 31483980 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 9 93 0 ENST00000358743.1:c.81G>A p.Arg27= p.R27= ENST00000358743 NM_134270.2 27 cgG/cgA 0 +SNAPC4 UCSF GRCh37 9 139277901 139277901 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 49 124 0 ENST00000298532.2:c.1720C>T p.Pro574Ser p.P574S ENST00000298532 NM_003086.2 574 Cct/Tct 0 +SNAPC4 UCSF GRCh37 9 139270934 139270934 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 14 59 0 ENST00000298532.2:c.4285-1G>A p.X1429_splice ENST00000298532 NM_003086.2 0 +SND1 UCSF GRCh37 7 127361376 127361376 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 150 52 168 0 ENST00000354725.3:c.1074G>A p.Val358= p.V358= ENST00000354725 NM_014390.2 358 gtG/gtA 0 +SNIP1 UCSF GRCh37 1 38006318 38006318 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 323 60 502 0 ENST00000296215.6:c.366G>A p.Arg122= p.R122= ENST00000296215 NM_024700.3 122 cgG/cgA 0 +SNRNP35 UCSF GRCh37 12 123950397 123950397 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 35 212 0 ENST00000412157.2:c.325G>A p.Ala109Thr p.A109T ENST00000412157 NM_180699.3 109 Gcc/Acc 0 +SNRNP70 UCSF GRCh37 19 49601749 49601749 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 11 58 0 ENST00000598441.1:c.330+1G>A p.X110_splice ENST00000598441 0 +SNTG2 UCSF GRCh37 2 1204830 1204830 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 9 121 0 ENST00000308624.5:c.633G>A p.Arg211= p.R211= ENST00000308624 NM_018968.3 211 agG/agA 0 +SNX16 UCSF GRCh37 8 82752050 82752050 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 24 273 0 ENST00000396330.2:c.172C>T p.Pro58Ser p.P58S ENST00000396330 NM_022133.3 58 Cct/Tct 0 +SNX27 UCSF GRCh37 1 151584906 151584906 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 19 118 0 ENST00000368843.3:c.229C>T p.Pro77Ser p.P77S ENST00000368843 NM_030918.5 77 Ccg/Tcg 0 +SNX29 UCSF GRCh37 16 12571605 12571605 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 20 124 0 ENST00000566228.1:c.2067G>A p.Trp689Ter p.W689* ENST00000566228 NM_032167.3 689 tgG/tgA 0 +SNX8 UCSF GRCh37 7 2314805 2314805 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 22 195 0 ENST00000222990.3:c.360C>T p.Leu120= p.L120= ENST00000222990 NM_013321.2 120 ctC/ctT 0 +SOBP UCSF GRCh37 6 107955882 107955882 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 16 124 0 ENST00000317357.5:c.1834C>T p.Pro612Ser p.P612S ENST00000317357 NM_018013.3 612 Ccc/Tcc 0 +SORBS1 UCSF GRCh37 10 97192287 97192287 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 6 103 0 ENST00000371247.2:c.219C>T p.Leu73= p.L73= ENST00000371247 73 ctC/ctT 0 +SORBS3 UCSF GRCh37 8 22412459 22412459 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 8 47 0 ENST00000240123.7:c.186C>T p.Gly62= p.G62= ENST00000240123 NM_005775.4 62 ggC/ggT 0 +SORCS1 UCSF GRCh37 10 108366924 108366924 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 16 158 0 ENST00000344440.6:c.3165G>A p.Gln1055= p.Q1055= ENST00000344440 NM_001206571.1 1055 caG/caA 0 +SORL1 UCSF GRCh37 11 121498476 121498476 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 4 21 0 ENST00000260197.7:c.6577G>A p.Gly2193Arg p.G2193R ENST00000260197 NM_003105.5 2193 Ggg/Agg 0 +SOX11 UCSF GRCh37 2 5834108 5834108 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 139 30 184 0 ENST00000322002.3:c.1255C>T p.Pro419Ser p.P419S ENST00000322002 NM_003108.3 419 Ccg/Tcg 0 +SOX11 UCSF GRCh37 2 5833051 5833051 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 17 164 0 ENST00000322002.3:c.198G>A p.Lys66= p.K66= ENST00000322002 NM_003108.3 66 aaG/aaA 0 +SOX17 UCSF GRCh37 8 55370876 55370876 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 16 144 0 ENST00000297316.4:c.178G>A p.Gly60Ser p.G60S ENST00000297316 NM_022454.3 60 Ggc/Agc 0 +SOX4 UCSF GRCh37 6 21595585 21595585 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 71 0 ENST00000244745.1:c.820G>A p.Ala274Thr p.A274T ENST00000244745 NM_003107.2 274 Gca/Aca 0 +SP8 UCSF GRCh37 7 20824335 20824335 + missense_variant Missense_Mutation SNP G G C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 24 53 0 ENST00000418710.2:c.1101C>G p.Ser367Arg p.S367R ENST00000418710 NM_182700.4 367 agC/agG 0 +SPAG17 UCSF GRCh37 1 118539353 118539353 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 37 216 0 ENST00000336338.5:c.4790G>A p.Gly1597Asp p.G1597D ENST00000336338 NM_206996.2 1597 gGt/gAt 0 +SPAG17 UCSF GRCh37 1 118640307 118640307 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 40 317 0 ENST00000336338.5:c.997G>A p.Asp333Asn p.D333N ENST00000336338 NM_206996.2 333 Gat/Aat 0 +SPAM1 UCSF GRCh37 7 123593687 123593687 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 182 23 194 0 ENST00000340011.5:c.63C>T p.Ser21= p.S21= ENST00000340011 NM_003117.4 21 tcC/tcT 0 +SPATA13 UCSF GRCh37 13 24798455 24798455 + missense_variant,NMD_transcript_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 18 113 0 ENST00000382141.4:c.1388C>T p.Pro463Leu p.P463L ENST00000382141 463 cCt/cTt 0 +SPATA21 UCSF GRCh37 1 16736310 16736310 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 28 174 0 ENST00000335496.1:c.373C>T p.Pro125Ser p.P125S ENST00000335496 NM_198546.1 125 Cca/Tca 0 +SPATA22 UCSF GRCh37 17 3346536 3346536 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 14 240 0 ENST00000573128.1:c.832C>T p.Pro278Ser p.P278S ENST00000573128 278 Cca/Tca 0 +SPATA5 UCSF GRCh37 4 123844347 123844347 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 241 46 315 0 ENST00000274008.4:c.50G>A p.Gly17Asp p.G17D ENST00000274008 NM_145207.2 17 gGt/gAt 0 +SPATS2 UCSF GRCh37 12 49883272 49883272 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 122 73 277 0 ENST00000553127.1:c.130C>T p.Pro44Ser p.P44S ENST00000553127 44 Cct/Tct 0 +SPATS2 UCSF GRCh37 12 49919843 49919843 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 29 202 0 ENST00000553127.1:c.1443G>A p.Trp481Ter p.W481* ENST00000553127 481 tgG/tgA 0 +SPEG UCSF GRCh37 2 220353344 220353344 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 13 127 0 ENST00000312358.7:c.7983C>T p.Asn2661= p.N2661= ENST00000312358 NM_005876.4 2661 aaC/aaT 0 +SPINT3 UCSF GRCh37 20 44144178 44144178 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 92 292 0 ENST00000217428.6:c.71C>T p.Ala24Val p.A24V ENST00000217428 NM_006652.1 24 gCa/gTa 0 +SPNS1 UCSF GRCh37 16 28993752 28993752 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 24 127 0 ENST00000311008.11:c.1041C>T p.Leu347= p.L347= ENST00000311008 NM_032038.2 347 ctC/ctT 0 +SPOPL UCSF GRCh37 2 139308548 139308548 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 15 124 0 ENST00000280098.4:c.276C>T p.Ser92= p.S92= ENST00000280098 NM_001001664.2 92 agC/agT 0 +SPRYD4 UCSF GRCh37 12 56863083 56863083 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 28 172 0 ENST00000338146.5:c.346G>A p.Gly116Ser p.G116S ENST00000338146 NM_207344.3 116 Ggt/Agt 0 +SPSB4 UCSF GRCh37 3 140784965 140784965 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 6 30 0 ENST00000310546.2:c.19G>A p.Gly7Arg p.G7R ENST00000310546 NM_080862.1 7 Ggg/Agg 0 +SPTAN1 UCSF GRCh37 9 131388710 131388710 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 74 0 ENST00000372739.3:c.6320C>T p.Ala2107Val p.A2107V ENST00000372739 NM_001130438.2 2107 gCc/gTc 0 +SPTB UCSF GRCh37 14 65216827 65216827 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 25 164 0 ENST00000389722.3:c.6648C>T p.Thr2216= p.T2216= ENST00000389722 NM_001024858.2 2216 acC/acT 0 +SPTBN1 UCSF GRCh37 2 54876290 54876290 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 6 17 0 ENST00000356805.4:c.5165G>A p.Gly1722Glu p.G1722E ENST00000356805 NM_003128.2 1722 gGg/gAg 0 +SPTBN2 UCSF GRCh37 11 66481114 66481114 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 17 187 0 ENST00000533211.1:c.760C>T p.Leu254= p.L254= ENST00000533211 254 Ctg/Ttg 0 +SPTBN2 UCSF GRCh37 11 66466553 66466553 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 363 58 456 0 ENST00000533211.1:c.3777G>A p.Arg1259= p.R1259= ENST00000533211 1259 agG/agA 0 +SPTBN4 UCSF GRCh37 19 41021267 41021267 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 6 28 0 ENST00000352632.3:c.2815G>A p.Asp939Asn p.D939N ENST00000352632 939 Gac/Aac 0 +SPTBN4 UCSF GRCh37 19 40993674 40993674 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 7 57 0 ENST00000352632.3:c.240C>T p.Cys80= p.C80= ENST00000352632 80 tgC/tgT 0 +SPTBN5 UCSF GRCh37 15 42144889 42144889 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 59 174 0 ENST00000320955.6:c.10392C>T p.Asp3464= p.D3464= ENST00000320955 NM_016642.3 3464 gaC/gaT 0 +SQSTM1 UCSF GRCh37 5 179250015 179250015 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 20 145 0 ENST00000389805.4:c.263C>T p.Ser88Phe p.S88F ENST00000389805 NM_003900.4 88 tCc/tTc 0 +SRCAP UCSF GRCh37 16 30715577 30715577 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 18 168 0 ENST00000262518.4:c.247G>A p.Ala83Thr p.A83T ENST00000262518 NM_006662.2 83 Gct/Act 0 +SREBF2 UCSF GRCh37 22 42280908 42280908 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 9 80 0 ENST00000361204.4:c.2101G>A p.Ala701Thr p.A701T ENST00000361204 NM_004599.3 701 Gct/Act 0 +SREBF2 UCSF GRCh37 22 42263059 42263059 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 417 70 556 0 ENST00000361204.4:c.313G>A p.Ala105Thr p.A105T ENST00000361204 NM_004599.3 105 Gcc/Acc 0 +SRGAP1 UCSF GRCh37 12 64536324 64536324 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 35 279 0 ENST00000355086.3:c.3130C>T p.Pro1044Ser p.P1044S ENST00000355086 NM_020762.2 1044 Ccc/Tcc 0 +SRGAP1 UCSF GRCh37 12 64410738 64410738 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 15 181 0 ENST00000355086.3:c.435G>A p.Glu145= p.E145= ENST00000355086 NM_020762.2 145 gaG/gaA 0 +SRM UCSF GRCh37 1 11116668 11116668 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 11 73 0 ENST00000376957.2:c.528C>T p.Asp176= p.D176= ENST00000376957 NM_003132.2 176 gaC/gaT 0 +SRRM2 UCSF GRCh37 16 2819002 2819002 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 84 216 0 ENST00000301740.8:c.7738C>T p.Pro2580Ser p.P2580S ENST00000301740 NM_016333.3 2580 Ccc/Tcc 0 +SRRM2 UCSF GRCh37 16 2806587 2806587 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 25 64 0 ENST00000301740.8:c.222G>A p.Glu74= p.E74= ENST00000301740 NM_016333.3 74 gaG/gaA 0 +SRRM3 UCSF GRCh37 7 75877587 75877587 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 6 26 0 ENST00000326382.8:c.315G>A p.Glu105= p.E105= ENST00000326382 NM_001110199.1 105 gaG/gaA 0 +SRRM5 UCSF GRCh37 19 44118416 44118416 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 99 20 146 0 ENST00000300811.3:c.41C>T p.Ala14Val p.A14V ENST00000300811 NM_182498.3 14 gCc/gTc 0 +SRY UCSF GRCh37 Y 2655091 2655091 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 17 113 0 ENST00000383070.1:c.554C>T p.Pro185Leu p.P185L ENST00000383070 NM_003140.2 185 cCc/cTc 0 +SSPN UCSF GRCh37 12 26348790 26348790 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 17 118 0 ENST00000242729.2:c.185C>T p.Ala62Val p.A62V ENST00000242729 NM_005086.4 62 gCc/gTc 0 +SSPO UCSF GRCh37 7 149488952 149488952 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 138 17 127 0 ENST00000378016.2:n.5293C>T *1765* ENST00000378016 0 +SSPO UCSF GRCh37 7 149479365 149479365 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 26 206 0 ENST00000378016.2:n.1878C>T *626* ENST00000378016 0 +SSTR1 UCSF GRCh37 14 38679367 38679367 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 62 205 0 ENST00000267377.2:c.773G>A p.Gly258Asp p.G258D ENST00000267377 NM_001049.2 258 gGc/gAc 0 +ST14 UCSF GRCh37 11 130068262 130068262 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 9 86 0 ENST00000278742.5:c.1519G>A p.Val507Ile p.V507I ENST00000278742 NM_021978.3 507 Gtc/Atc 0 +ST6GAL1 UCSF GRCh37 3 186760523 186760523 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 27 242 0 ENST00000169298.3:c.32G>A p.Ser11Asn p.S11N ENST00000169298 NM_173216.2 11 aGc/aAc 0 +ST6GALNAC1 UCSF GRCh37 17 74622111 74622111 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 18 104 0 ENST00000156626.7:c.1482C>T p.Asp494= p.D494= ENST00000156626 NM_018414.3 494 gaC/gaT 0 +STAB1 UCSF GRCh37 3 52554234 52554234 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 444 77 586 0 ENST00000321725.6:c.5427C>T p.Asp1809= p.D1809= ENST00000321725 NM_015136.2 1809 gaC/gaT 0 +STAG1 UCSF GRCh37 3 136068156 136068156 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 9 88 0 ENST00000383202.2:c.3115G>A p.Glu1039Lys p.E1039K ENST00000383202 NM_005862.2 1039 Gag/Aag 0 +STAG1 UCSF GRCh37 3 136136787 136136787 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 29 276 0 ENST00000383202.2:c.2136C>T p.Leu712= p.L712= ENST00000383202 NM_005862.2 712 ctC/ctT 0 +STARD7 UCSF GRCh37 2 96859011 96859011 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 214 34 361 0 ENST00000337288.5:c.629C>T p.Ser210Phe p.S210F ENST00000337288 NM_020151.3 210 tCc/tTc 0 +STAT5A UCSF GRCh37 17 40458446 40458446 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 4 22 0 ENST00000345506.4:c.1661C>T p.Ser554Phe p.S554F ENST00000345506 NM_003152.3 554 tCc/tTc 0 +STC2 UCSF GRCh37 5 172755116 172755116 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 79 289 0 ENST00000265087.4:c.81C>T p.Ala27= p.A27= ENST00000265087 NM_003714.2 27 gcC/gcT 0 +STIM2 UCSF GRCh37 4 27024410 27024410 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 369 67 566 0 ENST00000465503.1:c.2057C>T p.Ser686Phe p.S686F ENST00000465503 686 tCc/tTc 0 +STIM2 UCSF GRCh37 4 27004714 27004714 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 6 57 0 ENST00000465503.1:c.969G>A p.Gln323= p.Q323= ENST00000465503 323 caG/caA 0 +STK10 UCSF GRCh37 5 171510076 171510076 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 15 112 0 ENST00000176763.5:c.1698C>T p.Leu566= p.L566= ENST00000176763 NM_005990.3 566 ctC/ctT 0 +STK25 UCSF GRCh37 2 242441087 242441087 + missense_variant Missense_Mutation SNP G G A 1000g2011may_all_0.0010 P24_Rec2 Untested WXS Illumina HiSeq 235 42 378 0 ENST00000316586.4:c.67C>T p.Leu23Phe p.L23F ENST00000316586 NM_001282308.1 23 Ctc/Ttc 0 +STK4 UCSF GRCh37 20 43615866 43615866 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 24 225 0 ENST00000372806.3:c.454G>A p.Ala152Thr p.A152T ENST00000372806 NM_006282.2 152 Gca/Aca 0 +STK4 UCSF GRCh37 20 43623731 43623731 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 18 131 0 ENST00000372806.3:c.526G>A p.Asp176Asn p.D176N ENST00000372806 NM_006282.2 176 Gat/Aat 0 +STON1 UCSF GRCh37 2 48807954 48807954 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 296 45 506 0 ENST00000309835.3:c.182C>T p.Pro61Leu p.P61L ENST00000309835 61 cCt/cTt 0 +STT3A UCSF GRCh37 11 125482999 125482999 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 182 23 265 0 ENST00000392708.4:c.1481G>A p.Gly494Asp p.G494D ENST00000392708 NM_001278503.1 494 gGt/gAt 0 +STX17 UCSF GRCh37 9 102713352 102713352 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 123 23 191 0 ENST00000259400.6:c.200C>T p.Ser67Phe p.S67F ENST00000259400 NM_017919.2 67 tCc/tTc 0 +STX18 UCSF GRCh37 4 4440217 4440217 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 84 209 0 ENST00000306200.2:c.517C>T p.Pro173Ser p.P173S ENST00000306200 NM_016930.2 173 Cca/Tca 0 +STXBP5 UCSF GRCh37 6 147680301 147680301 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 24 242 0 ENST00000321680.6:c.2387C>T p.Ala796Val p.A796V ENST00000321680 NM_001127715.2 796 gCt/gTt 0 +STXBP5L UCSF GRCh37 3 120973866 120973866 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 16 157 0 ENST00000273666.6:c.1566G>A p.Trp522Ter p.W522* ENST00000273666 NM_014980.2 522 tgG/tgA 0 +SUGP2 UCSF GRCh37 19 19115330 19115330 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 573 83 621 0 ENST00000601879.1:c.2576G>A p.Gly859Asp p.G859D ENST00000601879 859 gGt/gAt 0 +SULT1C2 UCSF GRCh37 2 108921630 108921630 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 7 59 0 ENST00000326853.5:c.538G>A p.Val180Ile p.V180I ENST00000326853 NM_176825.2 180 Gtt/Att 0 +SUOX UCSF GRCh37 12 56397638 56397638 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 118 354 0 ENST00000394109.3:c.465C>T p.Tyr155= p.Y155= ENST00000394109 155 taC/taT 0 +SUPV3L1 UCSF GRCh37 10 70949174 70949174 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 8 86 0 ENST00000359655.4:c.724G>A p.Glu242Lys p.E242K ENST00000359655 NM_003171.3 242 Gaa/Aaa 0 +SURF2 UCSF GRCh37 9 136226929 136226929 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 8 89 0 ENST00000371964.4:c.441G>A p.Arg147= p.R147= ENST00000371964 NM_001278928.1 147 cgG/cgA 0 +SUV420H1 UCSF GRCh37 11 67926313 67926313 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 15 132 0 ENST00000304363.4:c.1500C>T p.Ala500= p.A500= ENST00000304363 NM_017635.3 500 gcC/gcT 0 +SV2B UCSF GRCh37 15 91769927 91769927 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 7 110 0 ENST00000394232.1:c.434C>T p.Ser145Phe p.S145F ENST00000394232 NM_014848.4 145 tCc/tTc 0 +SWT1 UCSF GRCh37 1 185259900 185259900 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 68 12 145 0 ENST00000367500.4:c.2668G>A p.Gly890Arg p.G890R ENST00000367500 NM_017673.6 890 Gga/Aga 0 +SYAP1 UCSF GRCh37 X 16773095 16773095 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 18 80 0 ENST00000380155.3:c.603C>T p.Asn201= p.N201= ENST00000380155 NM_032796.3 201 aaC/aaT 0 +SYMPK UCSF GRCh37 19 46331177 46331177 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 9 83 0 ENST00000245934.7:c.1986-1G>A p.X662_splice ENST00000245934 NM_004819.2 0 +SYMPK UCSF GRCh37 19 46355767 46355767 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 271 38 422 0 ENST00000245934.7:c.198C>T p.Asp66= p.D66= ENST00000245934 NM_004819.2 66 gaC/gaT 0 +SYN1 UCSF GRCh37 X 47478988 47478988 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 4 55 0 ENST00000295987.7:c.140G>A p.Gly47Glu p.G47E ENST00000295987 NM_006950.3 47 gGg/gAg 0 +SYNE1 UCSF GRCh37 6 152725353 152725353 + missense_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 23 101 0 ENST00000367255.5:c.6820C>A p.Leu2274Ile p.L2274I ENST00000367255 NM_182961.3 2274 Ctt/Att 0 +SYNE1 UCSF GRCh37 6 152665324 152665324 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 19 89 0 ENST00000367255.5:c.12117C>T p.Val4039= p.V4039= ENST00000367255 NM_182961.3 4039 gtC/gtT 0 +SYNE2 UCSF GRCh37 14 64626029 64626029 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 22 178 0 ENST00000358025.3:c.15964-1G>A p.X5322_splice ENST00000358025 NM_182914.2 0 +SYT16 UCSF GRCh37 14 62547594 62547594 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 14 75 0 ENST00000430451.2:c.1036G>A p.Glu346Lys p.E346K ENST00000430451 NM_031914.2 346 Gag/Aag 0 +SYT5 UCSF GRCh37 19 55686648 55686648 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 26 153 1 ENST00000354308.3:c.600C>T p.Arg200= p.R200= ENST00000354308 NM_003180.2 200 cgC/cgT 0 +SYT9 UCSF GRCh37 11 7324534 7324534 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 13 71 0 ENST00000318881.6:c.410C>T p.Pro137Leu p.P137L ENST00000318881 NM_175733.3 137 cCc/cTc 0 +SZT2 UCSF GRCh37 1 43893377 43893377 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 6 48 0 ENST00000562955.1:c.3604C>T p.Pro1202Ser p.P1202S ENST00000562955 NM_015284.3 1202 Cct/Tct 0 +SZT2 UCSF GRCh37 1 43894075 43894075 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 17 97 0 ENST00000562955.1:c.3913C>T p.Pro1305Ser p.P1305S ENST00000562955 NM_015284.3 1305 Cct/Tct 0 +SZT2 UCSF GRCh37 1 43898012 43898012 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 156 25 239 0 ENST00000562955.1:c.5173G>A p.Ala1725Thr p.A1725T ENST00000562955 NM_015284.3 1725 Gca/Aca 0 +SZT2 UCSF GRCh37 1 43911930 43911930 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 12 144 0 ENST00000562955.1:c.8826G>A p.Gln2942= p.Q2942= ENST00000562955 NM_015284.3 2942 caG/caA 0 +TAAR9 UCSF GRCh37 6 132859688 132859688 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 315 52 425 0 ENST00000434551.1:c.260C>T p.Pro87Leu p.P87L ENST00000434551 NM_175057.3 87 cCc/cTc 0 +TAAR9 UCSF GRCh37 6 132859645 132859645 + missense_variant Missense_Mutation SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 312 49 408 0 ENST00000434551.1:c.217T>C p.Ser73Pro p.S73P ENST00000434551 NM_175057.3 73 Tcg/Ccg 0 +TACC1 UCSF GRCh37 8 38699936 38699936 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 21 131 0 ENST00000317827.4:c.2092C>G p.Leu698Val p.L698V ENST00000317827 NM_006283.2 698 Ctg/Gtg 0 +TACC3 UCSF GRCh37 4 1739337 1739337 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 15 120 0 ENST00000313288.4:c.1849C>T p.Pro617Ser p.P617S ENST00000313288 NM_006342.2 617 Ccc/Tcc 0 +TACR3 UCSF GRCh37 4 104579464 104579464 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 103 68 240 0 ENST00000304883.2:c.645C>T p.Ala215= p.A215= ENST00000304883 NM_001059.2 215 gcC/gcT 0 +TACSTD2 UCSF GRCh37 1 59042226 59042226 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 23 224 0 ENST00000371225.2:c.603C>T p.Ile201= p.I201= ENST00000371225 NM_002353.2 201 atC/atT 0 +TACSTD2 UCSF GRCh37 1 59042664 59042664 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 13 108 0 ENST00000371225.2:c.165C>T p.Cys55= p.C55= ENST00000371225 NM_002353.2 55 tgC/tgT 0 +TADA2B UCSF GRCh37 4 7056411 7056411 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 14 144 0 ENST00000310074.7:c.893G>A p.Gly298Glu p.G298E ENST00000310074 NM_152293.2 298 gGg/gAg 0 +TADA3 UCSF GRCh37 3 9829012 9829012 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 9 70 0 ENST00000301964.2:c.577G>A p.Gly193Arg p.G193R ENST00000301964 NM_006354.3 193 Ggg/Agg 0 +TAF9 UCSF GRCh37 5 68661436 68661436 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 341 45 482 0 ENST00000328663.4:c.129C>T p.Ala43= p.A43= ENST00000328663 NM_001015892.1 43 gcC/gcT 0 +TAOK3 UCSF GRCh37 12 118590125 118590125 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 405 76 566 0 ENST00000392533.3:c.2442C>T p.Ser814= p.S814= ENST00000392533 NM_016281.3 814 agC/agT 0 +TAP2 UCSF GRCh37 6 32800159 32800159 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 30 202 0 ENST00000374899.4:c.1223G>A p.Ser408Asn p.S408N ENST00000374899 NM_018833.2 408 aGc/aAc 0 +TAP2 UCSF GRCh37 6 32805988 32805988 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 23 7 43 0 ENST00000374899.4:c.23C>T p.Pro8Leu p.P8L ENST00000374899 NM_018833.2 8 cCc/cTc 0 +TARS UCSF GRCh37 5 33462252 33462252 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 18 79 0 ENST00000455217.2:c.1878C>T p.Ile626= p.I626= ENST00000455217 NM_001258438.1 626 atC/atT 0 +TAS1R2 UCSF GRCh37 1 19166441 19166441 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 111 24 183 0 ENST00000375371.3:c.2172C>T p.Tyr724= p.Y724= ENST00000375371 NM_152232.2 724 taC/taT 0 +TAS2R16 UCSF GRCh37 7 122634918 122634918 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 342 45 394 0 ENST00000249284.2:c.771G>A p.Trp257Ter p.W257* ENST00000249284 NM_016945.2 257 tgG/tgA 0 +TBC1D1 UCSF GRCh37 4 38138876 38138876 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 9 52 0 ENST00000261439.4:c.3427G>A p.Val1143Met p.V1143M ENST00000261439 NM_015173.3 1143 Gtg/Atg 0 +TBC1D16 UCSF GRCh37 17 77984245 77984245 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 108 17 140 0 ENST00000310924.2:c.493G>A p.Ala165Thr p.A165T ENST00000310924 NM_019020.3 165 Gcg/Acg 0 +TBC1D24 UCSF GRCh37 16 2548302 2548302 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 144 17 161 0 ENST00000293970.5:c.1047G>A p.Glu349= p.E349= ENST00000293970 NM_001199107.1 349 gaG/gaA 0 +TBC1D24 UCSF GRCh37 16 2549836 2549836 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 47 27 73 0 ENST00000293970.5:c.1207G>A p.Val403Met p.V403M ENST00000293970 NM_001199107.1 403 Gtg/Atg 0 +TBC1D2B UCSF GRCh37 15 78369778 78369778 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 21 4 35 0 ENST00000300584.3:c.217C>T p.Pro73Ser p.P73S ENST00000300584 NM_144572.1 73 Ccg/Tcg 0 +TBC1D9 UCSF GRCh37 4 141543756 141543756 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 24 253 0 ENST00000442267.2:c.3394G>A p.Asp1132Asn p.D1132N ENST00000442267 NM_015130.2 1132 Gac/Aac 0 +TBX19 UCSF GRCh37 1 168260609 168260609 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 12 74 0 ENST00000367821.3:c.415C>T p.Pro139Ser p.P139S ENST00000367821 NM_005149.2 139 Ccc/Tcc 0 +TBX20 UCSF GRCh37 7 35289735 35289735 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 5 47 0 ENST00000408931.3:c.208G>A p.Gly70Ser p.G70S ENST00000408931 NM_001077653.2 70 Ggc/Agc 0 +TBX4 UCSF GRCh37 17 59534957 59534957 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 15 90 0 ENST00000240335.1:c.246G>A p.Glu82= p.E82= ENST00000240335 NM_018488.2 82 gaG/gaA 0 +TCF25 UCSF GRCh37 16 89954120 89954120 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 3 68 0 ENST00000263346.8:c.609G>A p.Glu203= p.E203= ENST00000263346 NM_014972.2 203 gaG/gaA 0 +TCF7L1 UCSF GRCh37 2 85532455 85532455 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 38 199 0 ENST00000282111.3:c.918C>T p.Pro306= p.P306= ENST00000282111 NM_031283.2 306 ccC/ccT 0 +TCFL5 UCSF GRCh37 20 61488834 61488834 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 305 83 457 0 ENST00000335351.3:c.1151C>T p.Ala384Val p.A384V ENST00000335351 NM_006602.2 384 gCa/gTa 0 +TCHH UCSF GRCh37 1 152083914 152083914 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 480 100 754 0 ENST00000368804.1:c.1779G>A p.Glu593= p.E593= ENST00000368804 NM_007113.3 593 gaG/gaA 0 +TCIRG1 UCSF GRCh37 11 67815257 67815257 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 18 134 0 ENST00000265686.3:c.1449C>T p.Asn483= p.N483= ENST00000265686 NM_006019.3 483 aaC/aaT 0 +TCN2 UCSF GRCh37 22 31010439 31010439 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 8 48 0 ENST00000215838.3:c.531C>T p.Asp177= p.D177= ENST00000215838 177 gaC/gaT 0 +TCTE1 UCSF GRCh37 6 44250156 44250156 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 17 112 0 ENST00000371505.4:c.987G>A p.Lys329= p.K329= ENST00000371505 NM_182539.3 329 aaG/aaA 0 +TDP1 UCSF GRCh37 14 90429642 90429642 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 23 153 0 ENST00000335725.4:c.184C>T p.Pro62Ser p.P62S ENST00000335725 NM_018319.3 62 Cct/Tct 0 +TDRD7 UCSF GRCh37 9 100222459 100222459 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 22 85 0 ENST00000355295.4:c.856-1G>A p.X286_splice ENST00000355295 NM_014290.2 0 +TDRD9 UCSF GRCh37 14 104484461 104484461 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 8 105 0 ENST00000409874.4:c.2364C>T p.Tyr788= p.Y788= ENST00000409874 NM_153046.2 788 taC/taT 0 +TEC 7006 UCSF GRCh37 4 48230504 48230504 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 10 87 0 ENST00000381501.3:c.128G>A p.Gly43Asp p.G43D ENST00000381501 NM_003215.2 43 gGt/gAt 0 +TEKT3 UCSF GRCh37 17 15231345 15231345 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 27 193 0 ENST00000395930.1:c.627C>T p.Asp209= p.D209= ENST00000395930 NM_031898.2 209 gaC/gaT 0 +TEKT4 UCSF GRCh37 2 95542486 95542486 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 19 272 0 ENST00000295201.4:c.1280C>T p.Thr427Ile p.T427I ENST00000295201 NM_144705.2 427 aCc/aTc 0 +TET1 UCSF GRCh37 10 70412308 70412308 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 19 148 0 ENST00000373644.4:c.4418G>A p.Gly1473Asp p.G1473D ENST00000373644 NM_030625.2 1473 gGt/gAt 0 +TFAP2A UCSF GRCh37 6 10410254 10410254 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 19 126 0 ENST00000379604.2:c.360C>T p.Gly120= p.G120= ENST00000379604 NM_003220.2 120 ggC/ggT 0 +TFAP2D UCSF GRCh37 6 50712900 50712900 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 29 131 0 ENST00000008391.3:c.964G>A p.Ala322Thr p.A322T ENST00000008391 NM_172238.3 322 Gcc/Acc 0 +TFE3 UCSF GRCh37 X 48891659 48891659 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 19 87 0 ENST00000315869.7:c.993G>A p.Arg331= p.R331= ENST00000315869 NM_006521.4 331 cgG/cgA 0 +TGFB1 UCSF GRCh37 19 41858729 41858729 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 15 62 0 ENST00000221930.5:c.221C>T p.Pro74Leu p.P74L ENST00000221930 NM_000660.4 74 cCc/cTc 0 +THAP10 UCSF GRCh37 15 71184308 71184308 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 8 90 0 ENST00000249861.4:c.304G>A p.Glu102Lys p.E102K ENST00000249861 NM_020147.3 102 Gag/Aag 0 +THAP8 UCSF GRCh37 19 36526365 36526365 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 23 186 0 ENST00000292894.1:c.802G>A p.Asp268Asn p.D268N ENST00000292894 NM_152658.2 268 Gac/Aac 0 +THBS2 UCSF GRCh37 6 169646295 169646295 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 11 112 0 ENST00000366787.3:c.691G>A p.Gly231Arg p.G231R ENST00000366787 NM_003247.2 231 Gga/Aga 0 +THBS2 UCSF GRCh37 6 169622376 169622376 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 9 72 0 ENST00000366787.3:c.3189G>A p.Val1063= p.V1063= ENST00000366787 NM_003247.2 1063 gtG/gtA 0 +THBS3 UCSF GRCh37 1 155172176 155172176 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 19 130 0 ENST00000368378.3:c.974C>T p.Pro325Leu p.P325L ENST00000368378 NM_007112.4 325 cCc/cTc 0 +THRAP3 UCSF GRCh37 1 36752234 36752234 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 229 140 422 0 ENST00000354618.5:c.403C>T p.Pro135Ser p.P135S ENST00000354618 NM_005119.3 135 Cct/Tct 0 +THSD7B UCSF GRCh37 2 137990496 137990496 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 26 192 0 ENST00000272643.3:c.1943C>T p.Ala648Val p.A648V ENST00000272643 648 gCt/gTt 0 +THSD7B UCSF GRCh37 2 138378229 138378229 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 92 11 134 1 ENST00000272643.3:c.3741C>T p.Cys1247= p.C1247= ENST00000272643 1247 tgC/tgT 0 +TIAM1 UCSF GRCh37 21 32617945 32617945 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 11 94 0 ENST00000286827.3:c.1443C>T p.Gly481= p.G481= ENST00000286827 NM_003253.2 481 ggC/ggT 0 +TIAM2 UCSF GRCh37 6 155577830 155577830 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 10 62 0 ENST00000461783.3:c.4681C>T p.Leu1561Phe p.L1561F ENST00000461783 1561 Ctc/Ttc 0 +TIGD5 UCSF GRCh37 8 144680968 144680968 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 23 166 0 ENST00000504548.2:c.895G>A p.Asp299Asn p.D299N ENST00000504548 NM_032862.4 299 Gac/Aac 0 +TIGD6 UCSF GRCh37 5 149375414 149375414 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 339 48 567 0 ENST00000296736.3:c.498G>A p.Leu166= p.L166= ENST00000296736 NM_030953.3 166 ctG/ctA 0 +TIMELESS UCSF GRCh37 12 56822416 56822416 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 8 47 0 ENST00000553532.1:c.1325C>T p.Ala442Val p.A442V ENST00000553532 442 gCc/gTc 0 +TIMP3 UCSF GRCh37 22 33255238 33255238 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 76 16 142 0 ENST00000266085.6:c.510C>T p.Ser170= p.S170= ENST00000266085 NM_000362.4 170 tcC/tcT 0 +TINAG UCSF GRCh37 6 54212223 54212223 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 26 233 0 ENST00000259782.4:c.807C>T p.Ser269= p.S269= ENST00000259782 NM_014464.3 269 tcC/tcT 0 +TINAG UCSF GRCh37 6 54185408 54185408 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 17 175 0 ENST00000259782.4:c.387G>A p.Glu129= p.E129= ENST00000259782 NM_014464.3 129 gaG/gaA 0 +TKT UCSF GRCh37 3 53275214 53275214 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 25 258 0 ENST00000423516.1:c.273C>T p.Phe91= p.F91= ENST00000423516 NM_001258028.1 91 ttC/ttT 0 +TLCD1 UCSF GRCh37 17 27051565 27051565 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 26 142 0 ENST00000292090.3:c.707C>T p.Pro236Leu p.P236L ENST00000292090 NM_138463.3 236 cCc/cTc 0 +TLE1 UCSF GRCh37 9 84200524 84200524 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 5 70 0 ENST00000376499.3:c.2024G>A p.Gly675Asp p.G675D ENST00000376499 NM_005077.3 675 gGc/gAc 0 +TLE1 UCSF GRCh37 9 84249150 84249150 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 29 77 0 ENST00000376499.3:c.439C>T p.Pro147Ser p.P147S ENST00000376499 NM_005077.3 147 Cct/Tct 0 +TLK2 UCSF GRCh37 17 60598179 60598179 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 14 4 34 0 ENST00000346027.5:c.127G>A p.Gly43Arg p.G43R ENST00000346027 NM_006852.3 43 Gga/Aga 0 +TLK2 UCSF GRCh37 17 60598172 60598172 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 16 4 35 1 ENST00000346027.5:c.120C>T p.Cys40= p.C40= ENST00000346027 NM_006852.3 40 tgC/tgT 0 +TLN1 UCSF GRCh37 9 35711782 35711782 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 102 32 282 0 ENST00000314888.9:c.3689C>T p.Pro1230Leu p.P1230L ENST00000314888 NM_006289.3 1230 cCt/cTt 0 +TLX2 UCSF GRCh37 2 74742762 74742762 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 15 119 0 ENST00000233638.7:c.403G>A p.Ala135Thr p.A135T ENST00000233638 NM_016170.4 135 Gcg/Acg 0 +TM2D1 UCSF GRCh37 1 62175098 62175098 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 16 191 1 ENST00000371180.2:c.436C>T p.Pro146Ser p.P146S ENST00000371180 NM_032027.2 146 Cca/Tca 0 +TM4SF5 UCSF GRCh37 17 4675277 4675277 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 188 39 253 1 ENST00000270560.3:c.60C>T p.Val20= p.V20= ENST00000270560 NM_003963.2 20 gtC/gtT 0 +TM9SF2 UCSF GRCh37 13 100206648 100206648 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 31 283 0 ENST00000376387.4:c.1579G>A p.Gly527Arg p.G527R ENST00000376387 NM_004800.2 527 Gga/Aga 0 +TMC6 UCSF GRCh37 17 76122428 76122428 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 14 108 0 ENST00000590602.1:c.201C>T p.Leu67= p.L67= ENST00000590602 67 ctC/ctT 0 +TMC7 UCSF GRCh37 16 19033040 19033040 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 9 119 0 ENST00000304381.5:c.550C>T p.Leu184= p.L184= ENST00000304381 NM_024847.3 184 Ctg/Ttg 0 +TMCC2 UCSF GRCh37 1 205238657 205238657 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 192 24 295 0 ENST00000358024.3:c.1327G>A p.Ala443Thr p.A443T ENST00000358024 NM_014858.3 443 Gcc/Acc 0 +TMED3 UCSF GRCh37 15 79614385 79614385 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 15 155 0 ENST00000299705.5:c.483C>T p.Tyr161= p.Y161= ENST00000299705 NM_007364.2 161 taC/taT 0 +TMEM119 UCSF GRCh37 12 108985533 108985533 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 244 40 321 0 ENST00000392806.3:c.627G>A p.Glu209= p.E209= ENST00000392806 NM_181724.2 209 gaG/gaA 0 +TMEM130 UCSF GRCh37 7 98460878 98460878 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 24 259 0 ENST00000416379.2:c.231C>T p.Thr77= p.T77= ENST00000416379 77 acC/acT 0 +TMEM132D UCSF GRCh37 12 130184605 130184605 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 242 45 355 0 ENST00000422113.2:c.718G>A p.Val240Ile p.V240I ENST00000422113 NM_133448.2 240 Gtc/Atc 0 +TMEM132D UCSF GRCh37 12 130185023 130185023 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 29 235 0 ENST00000422113.2:c.300C>T p.Phe100= p.F100= ENST00000422113 NM_133448.2 100 ttC/ttT 0 +TMEM132E UCSF GRCh37 17 32962033 32962033 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 15 94 0 ENST00000321639.5:c.1634G>A p.Gly545Asp p.G545D ENST00000321639 NM_207313.1 545 gGc/gAc 0 +TMEM132E UCSF GRCh37 17 32965084 32965084 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 5 38 0 ENST00000321639.5:c.2788A>G p.Thr930Ala p.T930A ENST00000321639 NM_207313.1 930 Acg/Gcg 0 +TMEM169 UCSF GRCh37 2 216960818 216960818 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 5 55 0 ENST00000454545.1:c.132G>A p.Arg44= p.R44= ENST00000454545 NM_001142310.1 44 agG/agA 0 +TMEM181 UCSF GRCh37 6 158957817 158957817 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 28 8 54 0 ENST00000367090.3:c.339G>A p.Lys113= p.K113= ENST00000367090 NM_020823.1 113 aaG/aaA 0 +TMEM201 UCSF GRCh37 1 9661372 9661372 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 234 48 260 0 ENST00000340381.6:c.816G>A p.Arg272= p.R272= ENST00000340381 NM_001130924.2 272 cgG/cgA 0 +TMEM222 UCSF GRCh37 1 27660449 27660449 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 15 116 0 ENST00000374076.4:c.312G>A p.Lys104= p.K104= ENST00000374076 NM_032125.2 104 aaG/aaA 0 +TMEM25 UCSF GRCh37 11 118403728 118403728 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 157 21 165 0 ENST00000313236.5:c.479C>T p.Pro160Leu p.P160L ENST00000313236 NM_032780.3 160 cCg/cTg 0 +TMEM42 UCSF GRCh37 3 44903518 44903518 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 4 37 0 ENST00000302392.4:c.102G>A p.Arg34= p.R34= ENST00000302392 NM_144638.1 34 cgG/cgA 0 +TMEM53 UCSF GRCh37 1 45120392 45120392 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 73 12 106 0 ENST00000372237.3:c.673G>A p.Ala225Thr p.A225T ENST00000372237 NM_024587.2 225 Gcc/Acc 0 +TMEM55B UCSF GRCh37 14 20927400 20927400 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 20 71 0 ENST00000398020.4:c.676G>C p.Gly226Arg p.G226R ENST00000398020 NM_144568.2 226 Ggc/Cgc 0 +TMEM59 UCSF GRCh37 1 54518683 54518683 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 15 76 0 ENST00000234831.5:c.179C>T p.Thr60Ile p.T60I ENST00000234831 NM_004872.3 60 aCc/aTc 0 +TMEM62 UCSF GRCh37 15 43470893 43470893 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 10 141 0 ENST00000260403.2:c.1470C>T p.Thr490= p.T490= ENST00000260403 NM_024956.3 490 acC/acT 0 +TMEM8A UCSF GRCh37 16 427491 427491 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 20 95 0 ENST00000431232.2:c.394C>T p.Pro132Ser p.P132S ENST00000431232 NM_021259.2 132 Ccg/Tcg 0 +TMPRSS11A UCSF GRCh37 4 68788560 68788560 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 21 151 0 ENST00000334830.7:c.614C>T p.Ala205Val p.A205V ENST00000334830 205 gCt/gTt 0 +TMPRSS3 UCSF GRCh37 21 43808636 43808636 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 13 92 0 ENST00000291532.3:c.323-1G>A p.X108_splice ENST00000291532 NM_032404.2 0 +TMPRSS9 UCSF GRCh37 19 2415743 2415743 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 15 96 0 ENST00000332578.3:c.1547C>T p.Pro516Leu p.P516L ENST00000332578 NM_182973.1 516 cCc/cTc 0 +TMTC2 UCSF GRCh37 12 83251288 83251288 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 16 119 0 ENST00000321196.3:c.583G>A p.Val195Ile p.V195I ENST00000321196 NM_152588.1 195 Gtt/Att 0 +TNC UCSF GRCh37 9 117822222 117822222 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 15 154 0 ENST00000350763.4:c.4093C>T p.Leu1365Phe p.L1365F ENST00000350763 NM_002160.3 1365 Ctc/Ttc 0 +TNC UCSF GRCh37 9 117797614 117797614 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 5 72 0 ENST00000350763.4:c.5657-1G>A p.X1886_splice ENST00000350763 NM_002160.3 0 +TNFAIP3 UCSF GRCh37 6 138196016 138196016 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 19 70 0 ENST00000237289.4:c.330G>A p.Gln110= p.Q110= ENST00000237289 NM_001270507.1 110 caG/caA 0 +TNFRSF12A UCSF GRCh37 16 3071622 3071622 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 9 103 0 ENST00000326577.4:c.266C>T p.Thr89Ile p.T89I ENST00000326577 NM_016639.2 89 aCc/aTc 0 +TNFRSF12A UCSF GRCh37 16 3071303 3071303 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 18 3 30 0 ENST00000326577.4:c.182G>A p.Ser61Asn p.S61N ENST00000326577 NM_016639.2 61 aGc/aAc 0 +TNFRSF4 UCSF GRCh37 1 1149139 1149139 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 5 59 0 ENST00000379236.3:c.172C>T p.Arg58Cys p.R58C ENST00000379236 NM_003327.3 58 Cgc/Tgc 0 +TNN UCSF GRCh37 1 175063312 175063312 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 8 88 0 ENST00000239462.4:c.1511G>A p.Gly504Glu p.G504E ENST00000239462 NM_022093.1 504 gGa/gAa 0 +TNNI3 UCSF GRCh37 19 55666175 55666175 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 426 74 506 0 ENST00000344887.5:c.306C>T p.Ala102= p.A102= ENST00000344887 NM_000363.4 102 gcC/gcT 0 +TNR UCSF GRCh37 1 175304879 175304879 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 43 181 0 ENST00000367674.2:c.3599G>A p.Gly1200Asp p.G1200D ENST00000367674 1200 gGc/gAc 0 +TNRC6A UCSF GRCh37 16 24802848 24802848 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 19 216 0 ENST00000395799.3:c.2885C>T p.Thr962Ile p.T962I ENST00000395799 NM_014494.2 962 aCa/aTa 0 +TNRC6A UCSF GRCh37 16 24802814 24802814 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 154 33 236 0 ENST00000395799.3:c.2851G>A p.Asp951Asn p.D951N ENST00000395799 NM_014494.2 951 Gac/Aac 0 +TNRC6B UCSF GRCh37 22 40708906 40708906 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 190 35 272 0 ENST00000454349.2:c.4583G>A p.Gly1528Glu p.G1528E ENST00000454349 NM_001162501.1 1528 gGg/gAg 0 +TNS1 UCSF GRCh37 2 218682831 218682831 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 47 116 0 ENST00000171887.4:c.3912C>T p.Leu1304= p.L1304= ENST00000171887 NM_022648.4 1304 ctC/ctT 0 +TOM1 UCSF GRCh37 22 35713910 35713910 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 179 29 249 1 ENST00000411850.1:c.93C>T p.Ala31= p.A31= ENST00000411850 NM_001135732.1 31 gcC/gcT 0 +TOM1L2 UCSF GRCh37 17 17810816 17810816 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 8 52 0 ENST00000379504.3:c.82G>A p.Glu28Lys p.E28K ENST00000379504 NM_001082968.1 28 Gag/Aag 0 +TOMM20L UCSF GRCh37 14 58862680 58862680 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 7 68 0 ENST00000360945.2:c.5C>T p.Pro2Leu p.P2L ENST00000360945 NM_207377.2 2 cCc/cTc 0 +TOP3B UCSF GRCh37 22 22323107 22323107 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 79 13 133 0 ENST00000398793.2:c.622G>A p.Asp208Asn p.D208N ENST00000398793 NM_003935.3 208 Gac/Aac 0 +TOPBP1 UCSF GRCh37 3 133376764 133376764 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 5 47 0 ENST00000260810.5:c.241C>T p.Pro81Ser p.P81S ENST00000260810 NM_007027.3 81 Cct/Tct 0 +TOR1A UCSF GRCh37 9 132584870 132584870 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 184 38 267 0 ENST00000351698.4:c.434C>T p.Thr145Ile p.T145I ENST00000351698 NM_000113.2 145 aCc/aTc 0 +TOR1B UCSF GRCh37 9 132571844 132571844 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 18 172 0 ENST00000259339.2:c.993G>A p.Ser331= p.S331= ENST00000259339 NM_014506.1 331 tcG/tcA 0 +TOX2 UCSF GRCh37 20 42694411 42694411 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 30 209 0 ENST00000341197.4:c.1020C>T p.Leu340= p.L340= ENST00000341197 NM_001098797.1 340 ctC/ctT 0 +TP53 UCSF GRCh37 17 7576858 7576858 + frameshift_variant Frame_Shift_Del DEL G G - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 128 0 ENST00000269305.4:c.988delC p.Leu330PhefsTer15 p.L330Ffs*15 ENST00000269305 NM_001126112.2 330 Ctt/tt 0 +TP53I11 UCSF GRCh37 11 44958415 44958415 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 32 8 28 0 ENST00000533940.1:c.273C>T p.Val91= p.V91= ENST00000533940 NM_001258320.1 91 gtC/gtT 0 +TP73 UCSF GRCh37 1 3599662 3599662 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 97 25 154 0 ENST00000378295.4:c.104G>A p.Ser35Asn p.S35N ENST00000378295 NM_005427.3 35 aGc/aAc 0 +TPP2 UCSF GRCh37 13 103326689 103326689 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 4 36 0 ENST00000376065.4:c.3389C>T p.Ala1130Val p.A1130V ENST00000376065 NM_003291.2 1130 gCc/gTc 0 +TRADD UCSF GRCh37 16 67188669 67188669 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 25 194 0 ENST00000345057.4:c.822G>A p.Gln274= p.Q274= ENST00000345057 NM_003789.3 274 caG/caA 0 +TRAK2 UCSF GRCh37 2 202260088 202260088 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 199 37 268 0 ENST00000332624.3:c.849G>A p.Glu283= p.E283= ENST00000332624 NM_015049.2 283 gaG/gaA 0 +TRAM2 UCSF GRCh37 6 52370449 52370449 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 100 68 175 0 ENST00000182527.3:c.823G>A p.Glu275Lys p.E275K ENST00000182527 NM_012288.3 275 Gaa/Aaa 0 +TRAPPC10 UCSF GRCh37 21 45514041 45514041 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 14 125 0 ENST00000291574.4:c.3095C>T p.Ser1032Phe p.S1032F ENST00000291574 NM_003274.4 1032 tCc/tTc 0 +TRAPPC8 UCSF GRCh37 18 29522635 29522635 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 13 87 0 ENST00000283351.4:c.93C>T p.Leu31= p.L31= ENST00000283351 NM_014939.3 31 ctC/ctT 0 +TRIM29 UCSF GRCh37 11 120008482 120008482 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 23 196 0 ENST00000341846.5:c.258G>A p.Gly86= p.G86= ENST00000341846 NM_012101.3 86 ggG/ggA 0 +TRIM38 UCSF GRCh37 6 25972150 25972150 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 117 16 162 0 ENST00000357085.3:c.561G>A p.Gln187= p.Q187= ENST00000357085 NM_006355.3 187 caG/caA 0 +TRIM46 UCSF GRCh37 1 155156634 155156634 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 221 37 301 0 ENST00000334634.4:c.2248G>A p.Val750Ile p.V750I ENST00000334634 NM_001282378.1 750 Gtc/Atc 0 +TRIM59 UCSF GRCh37 3 160156831 160156831 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 19 171 0 ENST00000309784.4:c.141G>A p.Trp47Ter p.W47* ENST00000309784 NM_173084.2 47 tgG/tgA 0 +TRIM6 UCSF GRCh37 11 5624670 5624670 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 43 178 0 ENST00000354852.5:c.212G>A p.Gly71Asp p.G71D ENST00000354852 NM_001003819.3 71 gGc/gAc 0 +TRIM6 UCSF GRCh37 11 5631473 5631473 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 14 128 0 ENST00000354852.5:c.956G>A p.Arg319Lys p.R319K ENST00000354852 NM_001003819.3 319 aGa/aAa 0 +TRIM69 UCSF GRCh37 15 45051860 45051860 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 12 145 0 ENST00000559390.1:c.836G>A p.Ser279Asn p.S279N ENST00000559390 279 aGc/aAc 0 +TRIM8 UCSF GRCh37 10 104416075 104416075 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 20 163 0 ENST00000302424.7:c.981C>T p.His327= p.H327= ENST00000302424 NM_030912.2 327 caC/caT 0 +TRIOBP UCSF GRCh37 22 38121147 38121147 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 378 62 565 1 ENST00000406386.3:c.2584G>A p.Asp862Asn p.D862N ENST00000406386 NM_001039141.2 862 Gac/Aac 0 +TRIP11 UCSF GRCh37 14 92505980 92505980 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 4 46 0 ENST00000267622.4:c.50G>A p.Gly17Asp p.G17D ENST00000267622 NM_004239.3 17 gGt/gAt 0 +TRMT11 UCSF GRCh37 6 126329619 126329619 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 148 25 200 0 ENST00000334379.5:c.760+1G>A p.X254_splice ENST00000334379 NM_001031712.2 0 +TRO UCSF GRCh37 X 54949066 54949066 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 15 135 0 ENST00000173898.7:c.101C>T p.Thr34Ile p.T34I ENST00000173898 NM_001039705.2 34 aCt/aTt 0 +TRPC4 UCSF GRCh37 13 38211153 38211153 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 251 41 380 0 ENST00000379681.3:c.2836G>A p.Val946Ile p.V946I ENST00000379681 NM_001135955.1 946 Gtt/Att 0 +TRPM1 UCSF GRCh37 15 31330285 31330285 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 20 123 0 ENST00000542188.1:c.2452G>A p.Glu818Lys p.E818K ENST00000542188 NM_001252020.1 818 Gaa/Aaa 0 +TRPM8 UCSF GRCh37 2 234888831 234888831 + splice_acceptor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 53 0 ENST00000324695.4:c.2356-1G>A p.X786_splice ENST00000324695 NM_024080.4 0 +TRPM8 UCSF GRCh37 2 234851359 234851359 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 10 83 0 ENST00000324695.4:c.666C>T p.Asn222= p.N222= ENST00000324695 NM_024080.4 222 aaC/aaT 0 +TRPM8 UCSF GRCh37 2 234863816 234863816 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 236 27 345 0 ENST00000324695.4:c.1284G>A p.Gly428= p.G428= ENST00000324695 NM_024080.4 428 ggG/ggA 0 +TRPV2 UCSF GRCh37 17 16321100 16321100 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 8 96 0 ENST00000338560.7:c.118G>A p.Glu40Lys p.E40K ENST00000338560 NM_016113.4 40 Gag/Aag 0 +TRPV4 UCSF GRCh37 12 110222122 110222122 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 6 79 0 ENST00000418703.2:c.2457G>A p.Arg819= p.R819= ENST00000418703 NM_001177431.1 819 agG/agA 0 +TRUB2 UCSF GRCh37 9 131077889 131077889 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 21 198 0 ENST00000372890.4:c.335G>A p.Gly112Glu p.G112E ENST00000372890 NM_015679.1 112 gGa/gAa 0 +TSGA14 UCSF GRCh37 7 130041759 130041759 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 226 28 207 0 ENST00000223208.5:c.605G>A p.Arg202Lys p.R202K ENST00000223208 NM_018718.2 202 aGa/aAa 0 +TSNAXIP1 UCSF GRCh37 16 67855009 67855009 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 18 129 0 ENST00000388833.3:c.106C>T p.Gln36Ter p.Q36* ENST00000388833 NM_018430.2 36 Cag/Tag 0 +TSPYL2 UCSF GRCh37 X 53112164 53112164 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 17 67 0 ENST00000375442.4:c.484C>T p.Pro162Ser p.P162S ENST00000375442 NM_022117.3 162 Ccg/Tcg 0 +TSTD2 UCSF GRCh37 9 100367915 100367915 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 71 0 ENST00000341170.4:c.963C>T p.Phe321= p.F321= ENST00000341170 NM_139246.4 321 ttC/ttT 0 +TTBK1 UCSF GRCh37 6 43221096 43221096 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 11 80 1 ENST00000259750.4:c.324G>A p.Gln108= p.Q108= ENST00000259750 NM_032538.1 108 caG/caA 0 +TTC16 UCSF GRCh37 9 130491936 130491936 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 14 135 0 ENST00000373289.3:c.1841C>T p.Ser614Phe p.S614F ENST00000373289 NM_144965.1 614 tCc/tTc 0 +TTC17 UCSF GRCh37 11 43422997 43422997 + frameshift_variant,splice_region_variant Frame_Shift_Del DEL A A - NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 0 ENST00000039989.4:c.1223del p.Asn408IlefsTer47 p.N408Ifs*47 ENST00000039989 NM_018259.5 407 ggA/gg 0 +TTC24 UCSF GRCh37 1 156551840 156551840 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 13 83 0 ENST00000368236.3:c.684G>A p.Arg228= p.R228= ENST00000368236 NM_001105669.2 228 agG/agA 0 +TTC28 UCSF GRCh37 22 28693690 28693690 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 9 87 0 ENST00000397906.2:c.680C>T p.Thr227Ile p.T227I ENST00000397906 NM_001145418.1 227 aCc/aTc 0 +TTC3 UCSF GRCh37 21 38466339 38466339 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 37 14 116 0 ENST00000399017.2:c.636C>T p.Asp212= p.D212= ENST00000399017 NM_003316.3 212 gaC/gaT 0 +TTC5 UCSF GRCh37 14 20764555 20764555 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 6 61 0 ENST00000258821.3:c.690G>A p.Arg230= p.R230= ENST00000258821 NM_138376.2 230 agG/agA 0 +TTC8 UCSF GRCh37 14 89336424 89336424 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 197 27 296 0 ENST00000380656.2:c.931G>A p.Ala311Thr p.A311T ENST00000380656 NM_144596.2 311 Gca/Aca 0 +TTF2 UCSF GRCh37 1 117624491 117624491 + missense_variant Missense_Mutation SNP C C G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 39 162 0 ENST00000369466.4:c.1825C>G p.Leu609Val p.L609V ENST00000369466 NM_003594.3 609 Ctc/Gtc 0 +TTLL10 UCSF GRCh37 1 1116199 1116199 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 25 3 36 0 ENST00000379290.1:c.714C>T p.Ala238= p.A238= ENST00000379290 238 gcC/gcT 0 +TTN UCSF GRCh37 2 179422822 179422822 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 10 145 0 ENST00000589042.1:c.87259G>A p.Ala29087Thr p.A29087T ENST00000589042 NM_001267550.1 29087 Gca/Aca 0 +TTN UCSF GRCh37 2 179485448 179485448 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 256 43 428 0 ENST00000589042.1:c.45889G>A p.Val15297Ile p.V15297I ENST00000589042 NM_001267550.1 15297 Gta/Ata 0 +TTN UCSF GRCh37 2 179633595 179633595 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 220 30 317 0 ENST00000589042.1:c.8968G>A p.Val2990Met p.V2990M ENST00000589042 NM_001267550.1 2990 Gtg/Atg 0 +TTN UCSF GRCh37 2 179417827 179417827 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 98 12 146 0 ENST00000589042.1:c.89800C>T p.Pro29934Ser p.P29934S ENST00000589042 NM_001267550.1 29934 Cca/Tca 0 +TTN UCSF GRCh37 2 179587979 179587979 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 180 23 276 0 ENST00000589042.1:c.21755C>T p.Thr7252Ile p.T7252I ENST00000589042 NM_001267550.1 7252 aCc/aTc 0 +TTN UCSF GRCh37 2 179401238 179401238 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 13 132 0 ENST00000589042.1:c.100236C>T p.Ala33412= p.A33412= ENST00000589042 NM_001267550.1 33412 gcC/gcT 0 +TUBA3C UCSF GRCh37 13 19748285 19748285 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 4 29 0 ENST00000400113.3:c.1071C>T p.Tyr357= p.Y357= ENST00000400113 NM_006001.2 357 taC/taT 0 +TUBGCP5 UCSF GRCh37 15 22855156 22855156 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 6 26 0 ENST00000283645.4:c.1617G>A p.Gln539= p.Q539= ENST00000283645 NM_052903.4 539 caG/caA 0 +TUFM UCSF GRCh37 16 28855093 28855093 + stop_gained Nonsense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 11 4 13 0 ENST00000313511.3:c.1158G>A p.Trp386Ter p.W386* ENST00000313511 NM_003321.4 386 tgG/tgA 0 +TXLNB UCSF GRCh37 6 139591620 139591620 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 13 118 0 ENST00000358430.3:c.660G>A p.Glu220= p.E220= ENST00000358430 NM_153235.3 220 gaG/gaA 0 +TXNDC11 UCSF GRCh37 16 11773604 11773604 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 20 201 1 ENST00000283033.5:c.2324C>T p.Ser775Phe p.S775F ENST00000283033 NM_015914.5 775 tCc/tTc 0 +TXNL1 UCSF GRCh37 18 54281696 54281696 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 143 22 235 0 ENST00000217515.6:c.694C>T p.Pro232Ser p.P232S ENST00000217515 NM_004786.2 232 Cca/Tca 0 +TYW3 UCSF GRCh37 1 75229704 75229704 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 250 49 388 0 ENST00000370867.3:c.687C>T p.Ala229= p.A229= ENST00000370867 NM_138467.2 229 gcC/gcT 0 +UACA UCSF GRCh37 15 70975129 70975129 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 5 104 0 ENST00000322954.6:c.790G>A p.Glu264Lys p.E264K ENST00000322954 NM_018003.2 264 Gaa/Aaa 0 +UBA1 UCSF GRCh37 X 47074325 47074325 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 32 112 0 ENST00000335972.6:c.3174C>T p.Arg1058= p.R1058= ENST00000335972 NM_003334.3 1058 cgC/cgT 0 +UBA7 UCSF GRCh37 3 49846990 49846990 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 275 44 379 0 ENST00000333486.3:c.2073C>T p.His691= p.H691= ENST00000333486 NM_003335.2 691 caC/caT 0 +UBE2E2 UCSF GRCh37 3 23631264 23631264 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 24 215 0 ENST00000396703.1:c.548C>T p.Thr183Ile p.T183I ENST00000396703 NM_152653.3 183 aCc/aTc 0 +UBE2E2 UCSF GRCh37 3 23250183 23250183 + splice_region_variant,5_prime_UTR_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 36 113 0 ENST00000396703.1:c.-8G>A p.X3_splice ENST00000396703 NM_152653.3 0 +UBE2G2 UCSF GRCh37 21 46197237 46197237 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 48 182 0 ENST00000345496.2:c.221C>T p.Thr74Ile p.T74I ENST00000345496 NM_003343.5 74 aCc/aTc 0 +UBE2Q1 UCSF GRCh37 1 154525615 154525615 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 89 15 151 0 ENST00000292211.4:c.622G>A p.Glu208Lys p.E208K ENST00000292211 NM_017582.6 208 Gag/Aag 0 +UBE2U UCSF GRCh37 1 64680588 64680588 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 9 70 0 ENST00000371076.3:c.430C>T p.Leu144= p.L144= ENST00000371076 NM_152489.1 144 Cta/Tta 0 +UBE4B UCSF GRCh37 1 10211519 10211519 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 201 34 297 0 ENST00000343090.6:c.2826C>T p.Asn942= p.N942= ENST00000343090 NM_001105562.2 942 aaC/aaT 0 +UBL4A UCSF GRCh37 X 153713937 153713937 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 41 12 75 0 ENST00000369660.4:c.415G>A p.Ala139Thr p.A139T ENST00000369660 NM_014235.3 139 Gcc/Acc 0 +UBN1 UCSF GRCh37 16 4926992 4926992 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 25 151 0 ENST00000396658.4:c.3145G>A p.Val1049Ile p.V1049I ENST00000396658 NM_016936.3 1049 Gtc/Atc 0 +UBQLN2 UCSF GRCh37 X 56590846 56590846 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 19 58 0 ENST00000338222.5:c.540G>A p.Glu180= p.E180= ENST00000338222 NM_013444.3 180 gaG/gaA 0 +UBR1 UCSF GRCh37 15 43360098 43360098 + missense_variant,splice_region_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 19 11 35 0 ENST00000290650.4:c.796G>A p.Glu266Lys p.E266K ENST00000290650 NM_174916.2 266 Gag/Aag 0 +UBR1 UCSF GRCh37 15 43317174 43317174 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 110 14 156 0 ENST00000290650.4:c.2592G>A p.Pro864= p.P864= ENST00000290650 NM_174916.2 864 ccG/ccA 0 +UBR1 UCSF GRCh37 15 43346981 43346981 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 238 33 309 0 ENST00000290650.4:c.1398G>A p.Gln466= p.Q466= ENST00000290650 NM_174916.2 466 caG/caA 0 +UBR3 UCSF GRCh37 2 170917685 170917685 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 195 25 364 0 ENST00000418381.1:c.4882G>A p.Glu1628Lys p.E1628K ENST00000418381 NM_172070.3 1628 Gaa/Aaa 0 +UBR4 UCSF GRCh37 1 19525077 19525077 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 10 118 0 ENST00000375254.3:c.606C>T p.Asn202= p.N202= ENST00000375254 NM_020765.2 202 aaC/aaT 0 +UBR5 UCSF GRCh37 8 103317361 103317361 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 21 171 0 ENST00000520539.1:c.2779G>A p.Val927Ile p.V927I ENST00000520539 NM_015902.5 927 Gta/Ata 0 +UBR5 UCSF GRCh37 8 103266681 103266681 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 85 17 138 0 ENST00000520539.1:c.8249C>T p.Pro2750Leu p.P2750L ENST00000520539 NM_015902.5 2750 cCc/cTc 0 +UCK2 UCSF GRCh37 1 165859506 165859506 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 7 72 0 ENST00000367879.4:c.165G>A p.Gln55= p.Q55= ENST00000367879 NM_012474.4 55 caG/caA 0 +UCN3 UCSF GRCh37 10 5416100 5416100 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 407 73 227 0 ENST00000380433.3:c.417G>A p.Lys139= p.K139= ENST00000380433 NM_053049.2 139 aaG/aaA 0 +UFSP2 UCSF GRCh37 4 186329183 186329183 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 12 143 0 ENST00000264689.6:c.1028C>T p.Thr343Ile p.T343I ENST00000264689 NM_018359.3 343 aCa/aTa 0 +UGDH UCSF GRCh37 4 39512330 39512330 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 298 35 408 0 ENST00000316423.6:c.416G>A p.Ser139Asn p.S139N ENST00000316423 NM_001184701.1 139 aGt/aAt 0 +UGT2B10 UCSF GRCh37 4 69885857 69885857 + non_coding_transcript_exon_variant RNA SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 124 26 205 0 ENST00000505092.1:n.276G>A *92* ENST00000505092 0 +UGT2B11 UCSF GRCh37 4 70080370 70080370 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 7 64 0 ENST00000446444.1:c.71G>A p.Gly24Glu p.G24E ENST00000446444 NM_001073.1 24 gGa/gAa 0 +UHRF1BP1 UCSF GRCh37 6 34827090 34827090 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 22 175 0 ENST00000192788.5:c.2957C>T p.Ser986Phe p.S986F ENST00000192788 NM_017754.3 986 tCc/tTc 0 +ULK1 UCSF GRCh37 12 132379581 132379581 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 7 45 0 ENST00000321867.4:c.35G>A p.Gly12Asp p.G12D ENST00000321867 NM_003565.2 12 gGc/gAc 0 +ULK2 UCSF GRCh37 17 19741882 19741882 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 96 17 170 0 ENST00000395544.4:c.719C>T p.Thr240Ile p.T240I ENST00000395544 NM_014683.3 240 aCa/aTa 0 +ULK3 UCSF GRCh37 15 75131027 75131027 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 151 24 189 0 ENST00000440863.2:c.1059G>A p.Gln353= p.Q353= ENST00000440863 NM_001099436.1 353 caG/caA 0 +UMOD UCSF GRCh37 16 20360023 20360023 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 29 8 45 0 ENST00000570689.1:c.600C>T p.Arg200= p.R200= ENST00000570689 200 cgC/cgT 0 +UMODL1 UCSF GRCh37 21 43533867 43533867 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 11 103 0 ENST00000408989.2:c.2673C>T p.Val891= p.V891= ENST00000408989 NM_173568.3 891 gtC/gtT 0 +UNC13B UCSF GRCh37 9 35396476 35396476 + missense_variant Missense_Mutation SNP A A G snp132_rs17849220 P24_Rec2 Untested WXS Illumina HiSeq 179 37 413 0 ENST00000378495.3:c.3065A>G p.His1022Arg p.H1022R ENST00000378495 NM_006377.3 1022 cAt/cGt 0 +UNC13B UCSF GRCh37 9 35313986 35313986 + missense_variant,splice_region_variant Missense_Mutation SNP G G T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 7 94 0 ENST00000378495.3:c.1167G>T p.Glu389Asp p.E389D ENST00000378495 NM_006377.3 389 gaG/gaT 0 +UNC13D UCSF GRCh37 17 73839293 73839293 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 11 56 0 ENST00000207549.4:c.208C>T p.Pro70Ser p.P70S ENST00000207549 NM_199242.2 70 Cct/Tct 0 +UNC5C UCSF GRCh37 4 96123949 96123949 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 19 57 0 ENST00000453304.1:c.2069T>A p.Leu690Gln p.L690Q ENST00000453304 NM_003728.3 690 cTg/cAg 0 +UNC5C UCSF GRCh37 4 96166234 96166234 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 134 18 206 0 ENST00000453304.1:c.837G>A p.Gly279= p.G279= ENST00000453304 NM_003728.3 279 ggG/ggA 0 +UNC5D UCSF GRCh37 8 35648074 35648074 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 174 20 183 0 ENST00000404895.2:c.2855G>A p.Gly952Glu p.G952E ENST00000404895 NM_080872.2 952 gGa/gAa 0 +UNC79 UCSF GRCh37 14 94107551 94107551 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 125 21 210 0 ENST00000256339.4:c.5447C>T p.Pro1816Leu p.P1816L ENST00000256339 NM_020818.3 1816 cCt/cTt 0 +UNC79 UCSF GRCh37 14 94038423 94038423 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 5 68 0 ENST00000256339.4:c.1408G>A p.Val470Ile p.V470I ENST00000256339 NM_020818.3 470 Gta/Ata 0 +UNC80 UCSF GRCh37 2 210841652 210841652 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 6 54 0 ENST00000439458.1:c.8590G>A p.Ala2864Thr p.A2864T ENST00000439458 NM_032504.1 2864 Gca/Aca 0 +UNC80 UCSF GRCh37 2 210642283 210642283 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 14 109 0 ENST00000439458.1:c.600G>A p.Lys200= p.K200= ENST00000439458 NM_032504.1 200 aaG/aaA 0 +UPF3B UCSF GRCh37 X 118968844 118968844 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 47 238 0 ENST00000276201.2:c.1449G>A p.Glu483= p.E483= ENST00000276201 NM_080632.2 483 gaG/gaA 0 +UPK3B UCSF GRCh37 7 76142480 76142480 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 129 20 152 0 ENST00000419923.2:c.627-784G>A *209* ENST00000419923 0 +URB1 UCSF GRCh37 21 33691589 33691589 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 15 166 0 ENST00000382751.3:c.5730G>A p.Arg1910= p.R1910= ENST00000382751 NM_014825.2 1910 cgG/cgA 0 +UROD UCSF GRCh37 1 45478816 45478816 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 13 101 0 ENST00000246337.4:c.142G>A p.Glu48Lys p.E48K ENST00000246337 NM_000374.4 48 Gaa/Aaa 0 +USF1 UCSF GRCh37 1 161010078 161010078 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 19 164 0 ENST00000368021.3:c.757G>A p.Glu253Lys p.E253K ENST00000368021 NM_007122.4 253 Gag/Aag 0 +USH2A UCSF GRCh37 1 216243514 216243514 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 65 260 0 ENST00000307340.3:c.5978G>A p.Ser1993Asn p.S1993N ENST00000307340 NM_206933.2 1993 aGt/aAt 0 +USH2A UCSF GRCh37 1 216373016 216373016 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 56 28 97 0 ENST00000307340.3:c.3764G>A p.Ser1255Asn p.S1255N ENST00000307340 NM_206933.2 1255 aGt/aAt 0 +USP24 UCSF GRCh37 1 55603253 55603253 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 18 131 0 ENST00000294383.6:c.3136G>A p.Asp1046Asn p.D1046N ENST00000294383 NM_015306.2 1046 Gat/Aat 0 +USP26 UCSF GRCh37 X 132159747 132159747 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 29 202 0 ENST00000511190.1:c.2502G>A p.Gly834= p.G834= ENST00000511190 NM_031907.1 834 ggG/ggA 0 +USP35 UCSF GRCh37 11 77921284 77921284 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 26 209 0 ENST00000529308.1:c.2383G>A p.Val795Met p.V795M ENST00000529308 NM_020798.2 795 Gtg/Atg 0 +USP36 UCSF GRCh37 17 76832208 76832208 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 7 49 0 ENST00000542802.3:c.238C>T p.Pro80Ser p.P80S ENST00000542802 80 Ccg/Tcg 0 +USP37 UCSF GRCh37 2 219324517 219324517 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 104 49 235 0 ENST00000258399.3:c.2639C>T p.Ala880Val p.A880V ENST00000258399 NM_020935.2 880 gCt/gTt 0 +USP38 UCSF GRCh37 4 144136024 144136024 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 44 72 250 0 ENST00000307017.4:c.2895G>A p.Trp965Ter p.W965* ENST00000307017 NM_032557.5 965 tgG/tgA 0 +USP42 UCSF GRCh37 7 6187440 6187440 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 162 20 169 0 ENST00000306177.5:c.1303C>T p.Pro435Ser p.P435S ENST00000306177 NM_032172.2 435 Ccc/Tcc 0 +USP43 UCSF GRCh37 17 9603504 9603504 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 13 94 0 ENST00000285199.7:c.1473G>A p.Arg491= p.R491= ENST00000285199 NM_001267576.1 491 agG/agA 0 +USP43 UCSF GRCh37 17 9631785 9631785 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 16 162 0 ENST00000285199.7:c.2850G>A p.Gln950= p.Q950= ENST00000285199 NM_001267576.1 950 caG/caA 0 +USP49 UCSF GRCh37 6 41774193 41774193 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 6 45 0 ENST00000373006.1:c.529G>A p.Ala177Thr p.A177T ENST00000373006 NM_018561.3 177 Gcc/Acc 0 +USP54 UCSF GRCh37 10 75289484 75289484 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 127 31 290 0 ENST00000339859.4:c.2014C>T p.Pro672Ser p.P672S ENST00000339859 672 Cct/Tct 0 +USP54 UCSF GRCh37 10 75276770 75276770 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 6 113 0 ENST00000339859.4:c.3414G>A p.Arg1138= p.R1138= ENST00000339859 1138 agG/agA 0 +USP54 UCSF GRCh37 10 75279635 75279635 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 24 3 43 0 ENST00000339859.4:c.2598G>A p.Gln866= p.Q866= ENST00000339859 866 caG/caA 0 +UTP20 UCSF GRCh37 12 101755786 101755786 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 63 41 114 0 ENST00000261637.4:c.5738C>T p.Thr1913Ile p.T1913I ENST00000261637 NM_014503.2 1913 aCc/aTc 0 +UTP20 UCSF GRCh37 12 101728261 101728261 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 9 46 0 ENST00000261637.4:c.3620G>A p.Ser1207Asn p.S1207N ENST00000261637 NM_014503.2 1207 aGt/aAt 0 +UTP20 UCSF GRCh37 12 101763522 101763522 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 9 99 0 ENST00000261637.4:c.6408C>T p.Cys2136= p.C2136= ENST00000261637 NM_014503.2 2136 tgC/tgT 0 +UTY UCSF GRCh37 Y 15409660 15409660 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 11 75 0 ENST00000331397.4:c.3646C>T p.Pro1216Ser p.P1216S ENST00000331397 NM_001258267.1 1216 Ccc/Tcc 0 +UVRAG UCSF GRCh37 11 75851986 75851986 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 50 186 0 ENST00000356136.3:c.1629G>A p.Lys543= p.K543= ENST00000356136 NM_003369.3 543 aaG/aaA 0 +VAC14 UCSF GRCh37 16 70796792 70796792 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 53 13 140 0 ENST00000261776.5:c.1297C>T p.Pro433Ser p.P433S ENST00000261776 NM_018052.3 433 Cct/Tct 0 +VARS UCSF GRCh37 6 31748671 31748671 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 16 176 0 ENST00000375663.3:c.2694G>A p.Glu898= p.E898= ENST00000375663 NM_006295.2 898 gaG/gaA 0 +VCAN UCSF GRCh37 5 82835603 82835603 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 243 41 378 0 ENST00000265077.3:c.6781G>A p.Glu2261Lys p.E2261K ENST00000265077 NM_004385.4 2261 Gaa/Aaa 0 +VDAC1 UCSF GRCh37 5 133309511 133309511 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 142 22 246 0 ENST00000265333.3:c.731G>A p.Gly244Asp p.G244D ENST00000265333 NM_003374.2 244 gGt/gAt 0 +VENTX UCSF GRCh37 10 135053573 135053573 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 34 292 0 ENST00000325980.9:c.540G>A p.Leu180= p.L180= ENST00000325980 NM_014468.3 180 ctG/ctA 0 +VEPH1 UCSF GRCh37 3 157034872 157034872 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 121 17 174 0 ENST00000362010.2:c.1854G>A p.Gln618= p.Q618= ENST00000362010 NM_001167912.1 618 caG/caA 0 +VGLL1 UCSF GRCh37 X 135630884 135630884 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 30 140 207 0 ENST00000370634.3:c.351G>A p.Pro117= p.P117= ENST00000370634 NM_016267.3 117 ccG/ccA 0 +VIL1 UCSF GRCh37 2 219301264 219301264 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 133 25 179 0 ENST00000248444.5:c.1886G>A p.Gly629Glu p.G629E ENST00000248444 NM_007127.2 629 gGg/gAg 0 +VMO1 UCSF GRCh37 17 4689332 4689332 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 219 38 292 0 ENST00000328739.5:c.211G>A p.Gly71Ser p.G71S ENST00000328739 NM_182566.2 71 Ggc/Agc 0 +VPRBP UCSF GRCh37 3 51475506 51475506 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 221 45 365 0 ENST00000504652.1:c.921G>A p.Met307Ile p.M307I ENST00000504652 307 atG/atA 0 +VPRBP UCSF GRCh37 3 51440740 51440740 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 373 79 565 0 ENST00000423656.1:c.3015G>A p.Glu1005= p.E1005= ENST00000423656 1005 gaG/gaA 0 +VPS13A UCSF GRCh37 9 79959108 79959108 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 12 200 0 ENST00000360280.3:c.7066C>T p.Leu2356Phe p.L2356F ENST00000360280 NM_033305.2 2356 Ctt/Ttt 0 +VPS13B UCSF GRCh37 8 100887766 100887766 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 126 21 214 0 ENST00000358544.2:c.11941G>A p.Val3981Met p.V3981M ENST00000358544 NM_017890.4 3981 Gtg/Atg 0 +VPS13C UCSF GRCh37 15 62237972 62237972 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 242 41 347 0 ENST00000261517.5:c.5090G>A p.Ser1697Asn p.S1697N ENST00000261517 NM_020821.2 1697 aGt/aAt 0 +VPS13D UCSF GRCh37 1 12327930 12327930 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 43 8 65 0 ENST00000358136.3:c.1754C>T p.Ser585Phe p.S585F ENST00000358136 NM_015378.2 585 tCt/tTt 0 +VPS13D UCSF GRCh37 1 12364765 12364765 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 42 8 74 0 ENST00000358136.3:c.6419G>A p.Gly2140Asp p.G2140D ENST00000358136 NM_015378.2 2140 gGc/gAc 0 +VPS39 UCSF GRCh37 15 42453941 42453941 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 114 16 211 0 ENST00000318006.5:c.2491G>A p.Val831Met p.V831M ENST00000318006 NM_015289.2 831 Gtg/Atg 0 +VPS45 UCSF GRCh37 1 150064042 150064042 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 71 14 106 0 ENST00000369130.3:c.1116G>A p.Arg372= p.R372= ENST00000369130 NM_001279354.1 372 agG/agA 0 +VPS4B UCSF GRCh37 18 61064452 61064452 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 20 303 0 ENST00000238497.5:c.907C>T p.Pro303Ser p.P303S ENST00000238497 NM_004869.3 303 Ccc/Tcc 0 +VSIG8 UCSF GRCh37 1 159828607 159828607 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 66 11 72 0 ENST00000368100.1:c.145G>A p.Asp49Asn p.D49N ENST00000368100 NM_001013661.1 49 Gac/Aac 0 +VWA3A UCSF GRCh37 16 22130344 22130344 + missense_variant Missense_Mutation SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 6 76 0 ENST00000389398.5:c.1112A>G p.Glu371Gly p.E371G ENST00000389398 NM_173615.3 371 gAg/gGg 0 +VWF UCSF GRCh37 12 6101129 6101129 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 10 61 0 ENST00000261405.5:c.6654G>A p.Arg2218= p.R2218= ENST00000261405 NM_000552.3 2218 cgG/cgA 0 +WASL UCSF GRCh37 7 123336632 123336632 + splice_donor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 95 12 140 0 ENST00000223023.4:c.629+1G>A p.X210_splice ENST00000223023 NM_003941.3 0 +WBP4 UCSF GRCh37 13 41639412 41639412 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 15 132 0 ENST00000379487.3:c.251G>A p.Gly84Asp p.G84D ENST00000379487 NM_007187.3 84 gGc/gAc 0 +WBP5 UCSF GRCh37 X 102612721 102612721 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 31 82 0 ENST00000372661.3:c.109G>A p.Glu37Lys p.E37K ENST00000372661 NM_001006612.1 37 Gag/Aag 0 +WBSCR17 UCSF GRCh37 7 70853291 70853291 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 306 53 455 0 ENST00000333538.5:c.493C>T p.Leu165= p.L165= ENST00000333538 NM_022479.2 165 Ctg/Ttg 0 +WBSCR17 UCSF GRCh37 7 70885975 70885975 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 519 65 700 0 ENST00000333538.5:c.846C>T p.Asn282= p.N282= ENST00000333538 NM_022479.2 282 aaC/aaT 0 +WDFY3 UCSF GRCh37 4 85717804 85717804 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 101 15 186 0 ENST00000295888.4:c.3037G>A p.Glu1013Lys p.E1013K ENST00000295888 NM_014991.4 1013 Gaa/Aaa 0 +WDR11 UCSF GRCh37 10 122612079 122612079 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 24 191 0 ENST00000263461.6:c.130G>A p.Val44Ile p.V44I ENST00000263461 NM_018117.11 44 Gta/Ata 0 +WDR17 UCSF GRCh37 4 177061100 177061100 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 36 286 0 ENST00000280190.4:c.1489G>A p.Ala497Thr p.A497T ENST00000280190 497 Gca/Aca 0 +WDR34 UCSF GRCh37 9 131396082 131396082 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 118 26 172 0 ENST00000372715.2:c.1552G>A p.Glu518Lys p.E518K ENST00000372715 NM_052844.3 518 Gaa/Aaa 0 +WDR45 UCSF GRCh37 X 48933538 48933538 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 27 9 40 0 ENST00000356463.3:c.506G>A p.Ser169Asn p.S169N ENST00000356463 NM_007075.3 169 aGt/aAt 0 +WDR5B UCSF GRCh37 3 122133933 122133933 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 240 38 344 0 ENST00000330689.4:c.443C>T p.Thr148Ile p.T148I ENST00000330689 NM_019069.3 148 aCt/aTt 0 +WDR6 UCSF GRCh37 3 49051328 49051328 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 113 293 0 ENST00000395474.3:c.2451C>T p.Thr817= p.T817= ENST00000395474 NM_018031.3 817 acC/acT 0 +WDR66 UCSF GRCh37 12 122389392 122389392 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 49 11 83 0 ENST00000288912.4:c.1276G>A p.Glu426Lys p.E426K ENST00000288912 NM_144668.5 426 Gag/Aag 0 +WDR83 UCSF GRCh37 19 12780631 12780631 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 106 12 94 0 ENST00000418543.3:c.27G>A p.Arg9= p.R9= ENST00000418543 NM_001099737.2 9 cgG/cgA 0 +WDR87 UCSF GRCh37 19 38376127 38376127 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 60 221 0 ENST00000303868.5:c.8067G>A p.Met2689Ile p.M2689I ENST00000303868 NM_031951.3 2689 atG/atA 0 +WDR90 UCSF GRCh37 16 711344 711344 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 169 27 207 0 ENST00000293879.4:c.3516C>T p.Val1172= p.V1172= ENST00000293879 1172 gtC/gtT 0 +WDR92 UCSF GRCh37 2 68384413 68384413 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 33 110 0 ENST00000295121.6:c.163G>A p.Asp55Asn p.D55N ENST00000295121 NM_138458.3 55 Gac/Aac 0 +WISP1 UCSF GRCh37 8 134239654 134239654 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 12 50 0 ENST00000250160.6:c.805G>A p.Ala269Thr p.A269T ENST00000250160 NM_003882.3 269 Gca/Aca 0 +WIZ UCSF GRCh37 19 15536149 15536149 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 7 44 0 ENST00000263381.7:c.1512G>A p.Glu504= p.E504= ENST00000263381 NM_021241.2 504 gaG/gaA 0 +WNK2 UCSF GRCh37 9 96024314 96024314 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 85 0 ENST00000297954.4:c.3285C>T p.Asn1095= p.N1095= ENST00000297954 NM_001282394.1 1095 aaC/aaT 0 +WNT11 UCSF GRCh37 11 75902790 75902790 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 4 36 0 ENST00000322563.3:c.708C>T p.Asp236= p.D236= ENST00000322563 NM_004626.2 236 gaC/gaT 0 +WNT8A UCSF GRCh37 5 137426465 137426465 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 83 16 128 1 ENST00000398754.1:c.759G>A p.Glu253= p.E253= ENST00000398754 NM_058244.2 253 gaG/gaA 0 +WRN UCSF GRCh37 8 30999288 30999288 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 61 7 73 0 ENST00000298139.5:c.3230C>T p.Pro1077Leu p.P1077L ENST00000298139 NM_000553.4 1077 cCt/cTt 0 +WRN UCSF GRCh37 8 31015035 31015035 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 48 7 34 0 ENST00000298139.5:c.3971C>T p.Pro1324Leu p.P1324L ENST00000298139 NM_000553.4 1324 cCc/cTc 0 +WRN UCSF GRCh37 8 30977791 30977791 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 159 21 163 0 ENST00000298139.5:c.2481C>T p.Gly827= p.G827= ENST00000298139 NM_000553.4 827 ggC/ggT 0 +XAB2 UCSF GRCh37 19 7684699 7684699 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 213 84 246 0 ENST00000358368.4:c.2440G>A p.Val814Ile p.V814I ENST00000358368 NM_020196.2 814 Gtc/Atc 0 +XKR7 UCSF GRCh37 20 30584969 30584969 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 218 35 277 0 ENST00000562532.2:c.1449G>A p.Glu483= p.E483= ENST00000562532 NM_001011718.1 483 gaG/gaA 0 +XPO4 UCSF GRCh37 13 21417107 21417107 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 8 90 0 ENST00000255305.6:c.654G>A p.Gln218= p.Q218= ENST00000255305 218 caG/caA 0 +XPO7 UCSF GRCh37 8 21856752 21856752 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 10 54 0 ENST00000252512.9:c.2579C>T p.Ala860Val p.A860V ENST00000252512 NM_015024.4 860 gCc/gTc 0 +XRCC3 UCSF GRCh37 14 104165783 104165783 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 75 26 122 0 ENST00000553264.1:c.692G>A p.Arg231Lys p.R231K ENST00000553264 231 aGg/aAg 0 +XRN1 UCSF GRCh37 3 142131443 142131443 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 15 97 0 ENST00000264951.4:c.1656C>T p.Asp552= p.D552= ENST00000264951 NM_019001.3 552 gaC/gaT 0 +XYLT2 UCSF GRCh37 17 48432314 48432314 + missense_variant Missense_Mutation SNP A A T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 8 59 0 ENST00000017003.2:c.904A>T p.Ser302Cys p.S302C ENST00000017003 NM_022167.2 302 Agc/Tgc 0 +XYLT2 UCSF GRCh37 17 48434120 48434120 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 74 17 84 0 ENST00000017003.2:c.1731C>T p.Gly577= p.G577= ENST00000017003 NM_022167.2 577 ggC/ggT 0 +YARS2 UCSF GRCh37 12 32908188 32908188 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 64 12 64 0 ENST00000324868.8:c.621G>A p.Arg207= p.R207= ENST00000324868 NM_001040436.2 207 cgG/cgA 0 +YIF1B UCSF GRCh37 19 38799920 38799920 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 12 117 0 ENST00000339413.6:c.346G>A p.Asp116Asn p.D116N ENST00000339413 NM_001039673.2 116 Gac/Aac 0 +YME1L1 UCSF GRCh37 10 27420824 27420824 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 306 34 259 0 ENST00000326799.3:c.993C>T p.Val331= p.V331= ENST00000326799 NM_139312.2 331 gtC/gtT 0 +ZAN UCSF GRCh37 7 100391805 100391805 + intron_variant Intron SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 10 127 0 ENST00000546292.1:c.7850-1013C>T *2617* ENST00000546292 NM_173059.1 0 +ZBED4 UCSF GRCh37 22 50279926 50279926 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 9 157 0 ENST00000216268.5:c.2616G>A p.Glu872= p.E872= ENST00000216268 NM_014838.2 872 gaG/gaA 0 +ZBP1 UCSF GRCh37 20 56179653 56179653 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.012,1000g2011may_all_0.0614,snp132_rs6099680 P24_Rec2 Untested WXS Illumina HiSeq 275 40 402 0 ENST00000371173.3:c.1266G>A p.Gly422= p.G422= ENST00000371173 NM_001160417.1 422 ggG/ggA 0 +ZBTB10 UCSF GRCh37 8 81399803 81399803 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 266 34 356 0 ENST00000430430.1:c.758C>T p.Ser253Phe p.S253F ENST00000430430 253 tCc/tTc 0 +ZBTB2 UCSF GRCh37 6 151686972 151686972 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 372 68 540 0 ENST00000325144.4:c.1229G>A p.Cys410Tyr p.C410Y ENST00000325144 NM_020861.1 410 tGc/tAc 0 +ZBTB4 UCSF GRCh37 17 7365866 7365866 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 12 102 0 ENST00000311403.4:c.2435G>A p.Gly812Glu p.G812E ENST00000311403 NM_020899.3 812 gGg/gAg 0 +ZBTB4 UCSF GRCh37 17 7369919 7369919 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 34 15 53 0 ENST00000311403.4:c.202C>T p.Pro68Ser p.P68S ENST00000311403 NM_020899.3 68 Cca/Tca 0 +ZBTB45 UCSF GRCh37 19 59028727 59028727 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 189 30 215 0 ENST00000594051.1:c.314C>T p.Ala105Val p.A105V ENST00000594051 105 gCc/gTc 0 +ZBTB47 UCSF GRCh37 3 42701201 42701201 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 13 115 0 ENST00000232974.6:c.1354G>A p.Glu452Lys p.E452K ENST00000232974 452 Gag/Aag 0 +ZBTB47 UCSF GRCh37 3 42701253 42701253 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 10 83 0 ENST00000232974.6:c.1406G>A p.Gly469Asp p.G469D ENST00000232974 469 gGc/gAc 0 +ZBTB7A UCSF GRCh37 19 4054382 4054382 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 34 133 0 ENST00000322357.4:c.849G>A p.Leu283= p.L283= ENST00000322357 NM_015898.2 283 ctG/ctA 0 +ZC3H12B UCSF GRCh37 X 64718939 64718939 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 39 11 82 0 ENST00000338957.4:c.809G>A p.Arg270Lys p.R270K ENST00000338957 NM_001010888.3 270 aGa/aAa 0 +ZC3H12B UCSF GRCh37 X 64722305 64722305 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 119 50 223 1 ENST00000338957.4:c.1727C>T p.Ala576Val p.A576V ENST00000338957 NM_001010888.3 576 gCc/gTc 0 +ZC3H12C UCSF GRCh37 11 110007586 110007586 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 193 25 224 0 ENST00000278590.3:c.220G>A p.Gly74Arg p.G74R ENST00000278590 NM_033390.1 74 Ggg/Agg 0 +ZC3H12C UCSF GRCh37 11 110036273 110036273 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 218 30 261 0 ENST00000278590.3:c.2463G>A p.Arg821= p.R821= ENST00000278590 NM_033390.1 821 cgG/cgA 0 +ZC3H7B UCSF GRCh37 22 41745306 41745306 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 9 50 0 ENST00000352645.4:c.1948+1G>A p.X650_splice ENST00000352645 NM_017590.5 0 +ZC3HAV1 UCSF GRCh37 7 138761068 138761068 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 69 238 0 ENST00000242351.5:c.1661C>T p.Thr554Met p.T554M ENST00000242351 NM_020119.3 554 aCg/aTg 0 +ZC3HAV1L UCSF GRCh37 7 138720571 138720571 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 58 7 42 0 ENST00000275766.1:c.193G>A p.Ala65Thr p.A65T ENST00000275766 NM_080660.3 65 Gcc/Acc 0 +ZCCHC11 UCSF GRCh37 1 52991715 52991715 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 273 45 425 0 ENST00000257177.4:c.238C>T p.Leu80Phe p.L80F ENST00000257177 80 Ctt/Ttt 0 +ZCCHC2 UCSF GRCh37 18 60217659 60217659 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 13 136 0 ENST00000269499.5:c.1279G>A p.Glu427Lys p.E427K ENST00000269499 NM_017742.4 427 Gaa/Aaa 0 +ZCCHC3 UCSF GRCh37 20 279310 279310 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 44 122 0 ENST00000382352.3:c.1083G>A p.Gly361= p.G361= ENST00000382352 NM_033089.6 361 ggG/ggA 0 +ZDHHC13 UCSF GRCh37 11 19177349 19177349 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 216 34 320 0 ENST00000446113.2:c.880C>T p.Leu294= p.L294= ENST00000446113 NM_019028.2 294 Ctg/Ttg 0 +ZDHHC5 UCSF GRCh37 11 57467469 57467469 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 51 12 70 0 ENST00000287169.3:c.2114G>A p.Gly705Glu p.G705E ENST00000287169 NM_015457.2 705 gGg/gAg 0 +ZDHHC8 UCSF GRCh37 22 20132889 20132889 + intron_variant Intron SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 13 110 0 ENST00000405930.3:c.2126+1610G>A *709* ENST00000405930 NM_001185024.1 0 +ZFHX2 UCSF GRCh37 14 24001885 24001885 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 167 23 226 0 ENST00000419474.3:c.2450C>T p.Ser817Phe p.S817F ENST00000419474 NM_033400.2 817 tCc/tTc 0 +ZFHX3 UCSF GRCh37 16 72829408 72829408 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 84 29 247 0 ENST00000268489.5:c.7173C>T p.Tyr2391= p.Y2391= ENST00000268489 NM_006885.3 2391 taC/taT 0 +ZFHX4 UCSF GRCh37 8 77619971 77619971 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 120 15 173 0 ENST00000521891.2:c.2781G>A p.Glu927= p.E927= ENST00000521891 NM_024721.4 927 gaG/gaA 0 +ZFP106 UCSF GRCh37 15 42743419 42743419 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 146 29 182 0 ENST00000263805.4:c.982G>A p.Asp328Asn p.D328N ENST00000263805 NM_022473.1 328 Gac/Aac 0 +ZFP36 UCSF GRCh37 19 39898603 39898603 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 214 27 270 1 ENST00000597629.1:c.263G>A p.Arg88His p.R88H ENST00000597629 88 cGc/cAc 0 +ZFP41 UCSF GRCh37 8 144332454 144332454 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 17 371 0 ENST00000330701.4:c.441G>A p.Glu147= p.E147= ENST00000330701 NM_173832.4 147 gaG/gaA 0 +ZFPM2 UCSF GRCh37 8 106814665 106814665 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 182 29 280 0 ENST00000407775.2:c.2355C>T p.His785= p.H785= ENST00000407775 NM_012082.3 785 caC/caT 0 +ZFYVE1 UCSF GRCh37 14 73464894 73464894 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 22 200 0 ENST00000556143.1:c.613C>T p.Arg205Cys p.R205C ENST00000556143 NM_021260.2 205 Cgt/Tgt 0 +ZFYVE26 UCSF GRCh37 14 68282515 68282515 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 55 11 77 0 ENST00000347230.4:c.166G>A p.Ala56Thr p.A56T ENST00000347230 NM_015346.3 56 Gca/Aca 0 +ZFYVE9 UCSF GRCh37 1 52811820 52811820 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 31 25 71 0 ENST00000287727.3:c.4205G>A p.Gly1402Glu p.G1402E ENST00000287727 NM_004799.3 1402 gGa/gAa 0 +ZG16B UCSF GRCh37 16 2881803 2881803 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 72 19 132 0 ENST00000382280.3:c.270G>A p.Gln90= p.Q90= ENST00000382280 NM_145252.2 90 caG/caA 0 +ZMYND15 UCSF GRCh37 17 4647099 4647099 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 13 105 0 ENST00000573751.2:c.1335C>T p.Ala445= p.A445= ENST00000573751 445 gcC/gcT 0 +ZNF117 UCSF GRCh37 7 64438752 64438752 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 77 14 123 0 ENST00000282869.6:c.1197C>T p.His399= p.H399= ENST00000282869 NM_015852.3 399 caC/caT 0 +ZNF132 UCSF GRCh37 19 58945830 58945830 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 69 11 99 0 ENST00000254166.3:c.981C>T p.Thr327= p.T327= ENST00000254166 NM_003433.3 327 acC/acT 0 +ZNF155 UCSF GRCh37 19 44500799 44500799 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 115 22 171 0 ENST00000407951.2:c.823G>A p.Ala275Thr p.A275T ENST00000407951 NM_001260488.1 275 Gca/Aca 0 +ZNF177 UCSF GRCh37 19 9491788 9491788 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 170 23 206 0 ENST00000434737.2:c.781C>T p.His261Tyr p.H261Y ENST00000434737 261 Cat/Tat 0 +ZNF180 UCSF GRCh37 19 44981244 44981244 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 94 12 144 0 ENST00000221327.4:c.1454G>A p.Arg485Lys p.R485K ENST00000221327 NM_013256.4 485 aGa/aAa 0 +ZNF185 UCSF GRCh37 X 152100223 152100223 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 8 83 0 ENST00000535861.1:c.922C>T p.Pro308Ser p.P308S ENST00000535861 NM_001178106.1 308 Cca/Tca 0 +ZNF185 UCSF GRCh37 X 152083371 152083371 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 2 12 17 0 ENST00000535861.1:c.152G>A p.Arg51His p.R51H ENST00000535861 NM_001178106.1 51 cGc/cAc 0 +ZNF192 UCSF GRCh37 6 28116521 28116521 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 105 15 166 0 ENST00000330236.6:c.336G>A p.Lys112= p.K112= ENST00000330236 NM_001278122.1 112 aaG/aaA 0 +ZNF20 UCSF GRCh37 19 12244492 12244492 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 598 67 626 0 ENST00000334213.5:c.509C>T p.Pro170Leu p.P170L ENST00000334213 NM_001203250.1 170 cCc/cTc 0 +ZNF229 UCSF GRCh37 19 44933981 44933981 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 106 465 0 ENST00000588931.1:c.975G>A p.Glu325= p.E325= ENST00000588931 NM_014518.2 325 gaG/gaA 0 +ZNF24 UCSF GRCh37 18 32920385 32920385 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 16 136 0 ENST00000261332.6:c.230G>A p.Cys77Tyr p.C77Y ENST00000261332 NM_006965.2 77 tGc/tAc 0 +ZNF24 UCSF GRCh37 18 32920566 32920566 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 178 33 245 0 ENST00000261332.6:c.49C>T p.Pro17Ser p.P17S ENST00000261332 NM_006965.2 17 Cca/Tca 0 +ZNF24 UCSF GRCh37 18 32917559 32917559 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 181 34 289 0 ENST00000261332.6:c.744G>A p.Lys248= p.K248= ENST00000261332 NM_006965.2 248 aaG/aaA 0 +ZNF253 UCSF GRCh37 19 20003111 20003111 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 3 25 0 ENST00000589717.1:c.1055C>T p.Ser352Phe p.S352F ENST00000589717 NM_021047.2 352 tCc/tTc 0 +ZNF253 UCSF GRCh37 19 20003434 20003434 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 12 4 14 0 ENST00000589717.1:c.1378G>A p.Ala460Thr p.A460T ENST00000589717 NM_021047.2 460 Gct/Act 0 +ZNF259 UCSF GRCh37 11 116654325 116654325 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 88 21 112 0 ENST00000227322.3:c.902G>A p.Gly301Glu p.G301E ENST00000227322 NM_003904.3 301 gGa/gAa 0 +ZNF276 UCSF GRCh37 16 89790020 89790020 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.011,1000g2011may_all_0.0260,snp132_rs34629175 P24_Rec2 Untested WXS Illumina HiSeq 32 6 95 0 ENST00000443381.2:c.909C>T p.Pro303= p.P303= ENST00000443381 NM_001113525.1 303 ccC/ccT 0 +ZNF286A UCSF GRCh37 17 15611511 15611511 + missense_variant,NMD_transcript_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 33 7 94 0 ENST00000413242.2:c.284G>A p.Gly95Glu p.G95E ENST00000413242 95 gGa/gAa 0 +ZNF287 UCSF GRCh37 17 16456713 16456713 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 87 16 165 0 ENST00000395824.1:c.743C>T p.Thr248Ile p.T248I ENST00000395824 248 aCt/aTt 0 +ZNF292 UCSF GRCh37 6 87966064 87966064 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 215 31 294 0 ENST00000369577.3:c.2717C>T p.Ser906Phe p.S906F ENST00000369577 NM_015021.1 906 tCt/tTt 0 +ZNF295 UCSF GRCh37 21 43412147 43412147 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 144 21 195 0 ENST00000310826.5:c.2058G>A p.Lys686= p.K686= ENST00000310826 NM_001098402.1 686 aaG/aaA 0 +ZNF296 UCSF GRCh37 19 45575741 45575741 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 80 10 100 0 ENST00000303809.2:c.546G>A p.Leu182= p.L182= ENST00000303809 NM_145288.1 182 ctG/ctA 0 +ZNF318 UCSF GRCh37 6 43306112 43306112 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 164 37 234 0 ENST00000361428.2:c.5624G>A p.Arg1875Lys p.R1875K ENST00000361428 NM_014345.2 1875 aGg/aAg 0 +ZNF318 UCSF GRCh37 6 43323442 43323442 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 335 68 486 0 ENST00000361428.2:c.1630G>A p.Glu544Lys p.E544K ENST00000361428 NM_014345.2 544 Gag/Aag 0 +ZNF343 UCSF GRCh37 20 2463888 2463888 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 276 42 392 0 ENST00000278772.4:c.1719G>A p.Gly573= p.G573= ENST00000278772 NM_024325.4 573 ggG/ggA 0 +ZNF35 UCSF GRCh37 3 44694194 44694194 + splice_donor_variant Splice_Site SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 54 6 71 0 ENST00000396056.2:c.337+1G>A p.X113_splice ENST00000396056 NM_003420.3 0 +ZNF385C UCSF GRCh37 17 40183686 40183686 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 57 30 142 0 ENST00000436535.3:c.627C>T p.Ser209= p.S209= ENST00000436535 209 tcC/tcT 0 +ZNF396 UCSF GRCh37 18 32953488 32953488 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 7 70 0 ENST00000306346.1:c.494G>A p.Ser165Asn p.S165N ENST00000306346 NM_145756.2 165 aGc/aAc 0 +ZNF407 UCSF GRCh37 18 72775186 72775186 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 27 232 0 ENST00000299687.5:c.5509G>A p.Ala1837Thr p.A1837T ENST00000299687 NM_017757.2 1837 Gcg/Acg 0 +ZNF414 UCSF GRCh37 19 8576704 8576704 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 7 26 0 ENST00000393927.4:c.671C>T p.Pro224Leu p.P224L ENST00000393927 NM_001146175.1 224 cCg/cTg 0 +ZNF418 UCSF GRCh37 19 58437815 58437815 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 152 20 224 0 ENST00000396147.1:c.1734C>T p.Leu578= p.L578= ENST00000396147 NM_133460.1 578 ctC/ctT 0 +ZNF439 UCSF GRCh37 19 11979318 11979318 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 9 88 0 ENST00000304030.2:c.1434C>T p.Val478= p.V478= ENST00000304030 NM_152262.2 478 gtC/gtT 0 +ZNF44 UCSF GRCh37 19 12384680 12384680 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 395 44 420 0 ENST00000356109.5:c.534C>T p.His178= p.H178= ENST00000356109 NM_001164276.1 178 caC/caT 0 +ZNF460 UCSF GRCh37 19 57802913 57802913 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 130 23 202 0 ENST00000360338.3:c.1004C>T p.Pro335Leu p.P335L ENST00000360338 NM_006635.3 335 cCc/cTc 0 +ZNF48 UCSF GRCh37 16 30409691 30409691 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 399 75 496 0 ENST00000320159.2:c.1120C>T p.Leu374Phe p.L374F ENST00000320159 NM_152652.2 374 Ctt/Ttt 0 +ZNF496 UCSF GRCh37 1 247492641 247492641 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 18 151 0 ENST00000294753.4:c.240G>A p.Gln80= p.Q80= ENST00000294753 NM_032752.1 80 caG/caA 0 +ZNF513 UCSF GRCh37 2 27601401 27601401 + synonymous_variant Silent SNP A A G NOVEL P24_Rec2 Untested WXS Illumina HiSeq 38 22 78 0 ENST00000323703.6:c.732T>C p.Cys244= p.C244= ENST00000323703 NM_144631.5 244 tgT/tgC 0 +ZNF517 UCSF GRCh37 8 146033708 146033708 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 26 9 65 0 ENST00000359971.3:c.1407G>A p.Gln469= p.Q469= ENST00000359971 NM_213605.2 469 caG/caA 0 +ZNF518B UCSF GRCh37 4 10445190 10445190 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 208 32 277 1 ENST00000326756.3:c.2763G>A p.Arg921= p.R921= ENST00000326756 NM_053042.2 921 agG/agA 0 +ZNF521 UCSF GRCh37 18 22805963 22805963 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 165 30 217 0 ENST00000361524.3:c.1919G>A p.Gly640Asp p.G640D ENST00000361524 NM_015461.2 640 gGt/gAt 0 +ZNF526 UCSF GRCh37 19 42729057 42729057 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 269 37 377 0 ENST00000301215.3:c.502G>A p.Val168Ile p.V168I ENST00000301215 NM_133444.1 168 Gta/Ata 0 +ZNF543 UCSF GRCh37 19 57839308 57839308 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 131 29 196 0 ENST00000321545.4:c.478G>A p.Asp160Asn p.D160N ENST00000321545 NM_213598.3 160 Gat/Aat 0 +ZNF544 UCSF GRCh37 19 58757770 58757770 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.010,1000g2011may_all_0.00554 P24_Rec2 Untested WXS Illumina HiSeq 81 14 79 0 ENST00000269829.4:c.137C>T p.Thr46Ile p.T46I ENST00000269829 NM_014480.2 46 aCc/aTc 0 +ZNF544 UCSF GRCh37 19 58772931 58772931 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 172 40 238 0 ENST00000269829.4:c.959G>A p.Gly320Asp p.G320D ENST00000269829 NM_014480.2 320 gGc/gAc 0 +ZNF546 UCSF GRCh37 19 40521124 40521124 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 46 8 67 0 ENST00000347077.4:c.1947C>T p.Ser649= p.S649= ENST00000347077 NM_178544.3 649 agC/agT 0 +ZNF552 UCSF GRCh37 19 58319917 58319917 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 112 80 263 0 ENST00000391701.1:c.715C>T p.Pro239Ser p.P239S ENST00000391701 NM_024762.3 239 Cct/Tct 0 +ZNF563 UCSF GRCh37 19 12429560 12429560 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 45 5 54 0 ENST00000293725.5:c.1279G>A p.Gly427Arg p.G427R ENST00000293725 NM_145276.2 427 Ggg/Agg 0 +ZNF571 UCSF GRCh37 19 38056308 38056308 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 50 10 75 0 ENST00000328550.2:c.1022G>A p.Gly341Glu p.G341E ENST00000328550 341 gGg/gAg 0 +ZNF573 UCSF GRCh37 19 38230154 38230154 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 137 20 239 0 ENST00000590414.2:c.1237C>T p.Pro413Ser p.P413S ENST00000590414 413 Ccc/Tcc 0 +ZNF574 UCSF GRCh37 19 42584099 42584099 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 135 21 211 0 ENST00000600245.1:c.1341C>T p.Ala447= p.A447= ENST00000600245 447 gcC/gcT 0 +ZNF577 UCSF GRCh37 19 52376415 52376415 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 212 36 340 0 ENST00000301399.5:c.828G>A p.Gly276= p.G276= ENST00000301399 NM_032679.2 276 ggG/ggA 0 +ZNF585B UCSF GRCh37 19 37680656 37680656 + splice_acceptor_variant Splice_Site SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 298 55 509 0 ENST00000532828.2:c.200-1G>A p.X67_splice ENST00000532828 NM_152279.3 0 +ZNF593 UCSF GRCh37 1 26496631 26496631 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 140 24 204 0 ENST00000374266.5:c.157C>T p.Pro53Ser p.P53S ENST00000374266 NM_015871.4 53 Ccc/Tcc 0 +ZNF599 UCSF GRCh37 19 35250905 35250905 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 65 8 93 0 ENST00000329285.8:c.801G>A p.Arg267= p.R267= ENST00000329285 NM_001007248.2 267 agG/agA 0 +ZNF609 UCSF GRCh37 15 64967341 64967341 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 204 36 294 0 ENST00000326648.3:c.2288C>T p.Ser763Phe p.S763F ENST00000326648 NM_015042.1 763 tCt/tTt 0 +ZNF613 UCSF GRCh37 19 52448084 52448084 + synonymous_variant Silent SNP T T C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 239 30 358 0 ENST00000293471.6:c.948T>C p.His316= p.H316= ENST00000293471 NM_001031721.3 316 caT/caC 0 +ZNF618 UCSF GRCh37 9 116778436 116778436 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 59 12 113 0 ENST00000288466.7:c.702G>A p.Arg234= p.R234= ENST00000288466 NM_133374.2 234 agG/agA 0 +ZNF649 UCSF GRCh37 19 52394838 52394838 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 357 57 541 0 ENST00000354957.3:c.551G>A p.Gly184Glu p.G184E ENST00000354957 NM_023074.3 184 gGg/gAg 0 +ZNF662 UCSF GRCh37 3 42956793 42956793 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 187 110 427 0 ENST00000328199.6:c.1306C>T p.His436Tyr p.H436Y ENST00000328199 NM_001134656.1 436 Cat/Tat 0 +ZNF689 UCSF GRCh37 16 30615959 30615959 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 62 8 77 0 ENST00000287461.3:c.1129G>A p.Asp377Asn p.D377N ENST00000287461 NM_138447.2 377 Gac/Aac 0 +ZNF692 UCSF GRCh37 1 249151525 249151525 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 22 106 0 ENST00000451251.1:c.398C>T p.Pro133Leu p.P133L ENST00000451251 NM_001136036.2 133 cCt/cTt 0 +ZNF699 UCSF GRCh37 19 9415792 9415792 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 153 22 194 0 ENST00000591998.1:c.4G>A p.Glu2Lys p.E2K ENST00000591998 2 Gag/Aag 0 +ZNF700 UCSF GRCh37 19 12059222 12059222 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 36 4 34 0 ENST00000254321.5:c.383G>A p.Ser128Asn p.S128N ENST00000254321 NM_144566.2 128 aGc/aAc 0 +ZNF709 UCSF GRCh37 19 12575879 12575879 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 70 28 97 0 ENST00000397732.3:c.857G>A p.Gly286Asp p.G286D ENST00000397732 NM_152601.3 286 gGt/gAt 0 +ZNF711 UCSF GRCh37 X 84525896 84525896 + missense_variant Missense_Mutation SNP G G C NOVEL P24_Rec2 Untested WXS Illumina HiSeq 15 36 64 0 ENST00000373165.3:c.1348G>C p.Glu450Gln p.E450Q ENST00000373165 NM_021998.4 450 Gaa/Caa 0 +ZNF74 UCSF GRCh37 22 20754989 20754989 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 158 31 249 0 ENST00000400451.2:c.188C>T p.Pro63Leu p.P63L ENST00000400451 NM_003426.3 63 cCt/cTt 0 +ZNF768 UCSF GRCh37 16 30536258 30536258 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 81 10 96 0 ENST00000380412.5:c.1203C>T p.Phe401= p.F401= ENST00000380412 NM_024671.3 401 ttC/ttT 0 +ZNF770 UCSF GRCh37 15 35274747 35274747 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 109 146 600 0 ENST00000356321.4:c.889C>T p.Pro297Ser p.P297S ENST00000356321 NM_014106.3 297 Cca/Tca 0 +ZNF776 UCSF GRCh37 19 58265946 58265946 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 67 12 91 0 ENST00000317178.5:c.1448C>T p.Ser483Phe p.S483F ENST00000317178 NM_173632.3 483 tCt/tTt 0 +ZNF777 UCSF GRCh37 7 149152608 149152608 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 147 20 173 0 ENST00000247930.4:c.506C>T p.Ser169Phe p.S169F ENST00000247930 NM_015694.2 169 tCt/tTt 0 +ZNF780A UCSF GRCh37 19 40580810 40580810 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 113 16 141 0 ENST00000455521.1:c.1542C>T p.Tyr514= p.Y514= ENST00000455521 NM_001142577.1 514 taC/taT 0 +ZNF783 UCSF GRCh37 7 148963769 148963769 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 40 10 45 0 ENST00000434415.1:c.368G>A p.Arg123Lys p.R123K ENST00000434415 NM_001195220.1 123 aGg/aAg 0 +ZNF785 UCSF GRCh37 16 30594687 30594687 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 205 24 324 1 ENST00000395216.2:c.412G>A p.Val138Ile p.V138I ENST00000395216 NM_152458.6 138 Gtc/Atc 0 +ZNF827 UCSF GRCh37 4 146824083 146824083 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 93 22 249 0 ENST00000379448.4:c.328G>A p.Asp110Asn p.D110N ENST00000379448 NM_178835.3 110 Gac/Aac 0 +ZNF835 UCSF GRCh37 19 57175523 57175523 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 70 170 0 ENST00000537055.2:c.1044C>T p.His348= p.H348= ENST00000537055 NM_001005850.2 348 caC/caT 0 +ZNF836 UCSF GRCh37 19 52660772 52660772 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 90 13 149 0 ENST00000322146.8:c.164C>T p.Thr55Ile p.T55I ENST00000322146 NM_001102657.1 55 aCc/aTc 0 +ZNF850 UCSF GRCh37 19 37253264 37253264 + stop_gained Nonsense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 35 7 51 0 ENST00000591344.1:c.82C>T p.Gln28Ter p.Q28* ENST00000591344 NM_001193552.1 28 Cag/Tag 0 +ZNF91 UCSF GRCh37 19 23542428 23542428 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 17 3 12 0 ENST00000300619.7:c.3353C>T p.Ser1118Phe p.S1118F ENST00000300619 NM_003430.2 1118 tCc/tTc 0 +ZNF91 UCSF GRCh37 19 23543844 23543844 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 20 4 24 0 ENST00000300619.7:c.1937C>T p.Ala646Val p.A646V ENST00000300619 NM_003430.2 646 gCt/gTt 0 +ZNF92 UCSF GRCh37 7 64864293 64864293 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 6 38 0 ENST00000328747.7:c.1266G>A p.Glu422= p.E422= ENST00000328747 NM_152626.2 422 gaG/gaA 0 +ZNFX1 UCSF GRCh37 20 47887104 47887104 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 309 50 471 0 ENST00000396105.1:c.1245G>A p.Arg415= p.R415= ENST00000396105 NM_021035.2 415 agG/agA 0 +ZSCAN2 UCSF GRCh37 15 85147240 85147240 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 22 8 40 0 ENST00000448803.2:c.82G>A p.Glu28Lys p.E28K ENST00000448803 NM_181877.3 28 Gag/Aag 0 +ZSCAN2 UCSF GRCh37 15 85164314 85164314 + synonymous_variant Silent SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 82 15 111 0 ENST00000448803.2:c.888C>T p.His296= p.H296= ENST00000448803 NM_181877.3 296 caC/caT 0 +ZSCAN2 UCSF GRCh37 15 85164869 85164869 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 60 7 93 0 ENST00000448803.2:c.1443G>A p.Glu481= p.E481= ENST00000448803 NM_181877.3 481 gaG/gaA 0 +ZSCAN20 UCSF GRCh37 1 33954780 33954780 + missense_variant Missense_Mutation SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 107 29 152 0 ENST00000361328.3:c.670G>A p.Ala224Thr p.A224T ENST00000361328 NM_145238.3 224 Gct/Act 0 +ZSCAN29 UCSF GRCh37 15 43656390 43656390 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 166 27 233 0 ENST00000396976.2:c.1413C>T p.Ser471= p.S471= ENST00000396976 NM_152455.3 471 agC/agT 0 +ZSCAN5A UCSF GRCh37 19 56733157 56733157 + synonymous_variant Silent SNP G G A NOVEL P24_Rec2 Untested WXS Illumina HiSeq 78 12 97 0 ENST00000587340.1:c.1278C>T p.Tyr426= p.Y426= ENST00000587340 426 taC/taT 0 +ZW10 UCSF GRCh37 11 113619026 113619026 + missense_variant Missense_Mutation SNP C C T NOVEL P24_Rec2 Untested WXS Illumina HiSeq 210 26 340 0 ENST00000200135.3:c.1042G>A p.Val348Ile p.V348I ENST00000200135 NM_004724.3 348 Gtt/Att 0 +ABCA4 UCSF GRCh37 1 94497337 94497337 + synonymous_variant Silent SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 39 21 56 0 ENST00000370225.3:c.4125G>A p.Ala1375= p.A1375= ENST00000370225 NM_000350.2 1375 gcG/gcA 0 +ATRX UCSF GRCh37 X 76918873 76918874 + frameshift_variant,splice_region_variant Frame_Shift_Del DEL TT TT - NOVEL P25_Pri Untested WXS Illumina HiSeq 33 0 ENST00000373344.5:c.4117_4118del p.Lys1373GlyfsTer4 p.K1373Gfs*4 ENST00000373344 NM_000489.3 1373 AAg/g 0 +CCNA1 UCSF GRCh37 13 37007335 37007335 + stop_gained Nonsense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 48 47 110 0 ENST00000255465.4:c.274C>T p.Gln92Ter p.Q92* ENST00000255465 92 Cag/Tag 0 +CDHR5 UCSF GRCh37 11 618683 618683 + missense_variant Missense_Mutation SNP T T C 1000g2010nov_all_0.023,1000g2011may_all_0.0158 P25_Pri Untested WXS Illumina HiSeq 39 6 37 1 ENST00000358353.3:c.1876A>G p.Thr626Ala p.T626A ENST00000358353 626 Acc/Gcc 0 +CFHR4 UCSF GRCh37 1 196876134 196876134 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 51 38 92 0 ENST00000367416.2:c.580G>A p.Glu194Lys p.E194K ENST00000367416 NM_001201551.1 194 Gaa/Aaa 0 +DNAJC11 UCSF GRCh37 1 6727803 6727804 + frameshift_variant Frame_Shift_Del DEL TC TC - 1000g2010nov_all P25_Pri Untested WXS Illumina HiSeq 8 0 ENST00000377577.5:c.343_344delGA p.Glu115ArgfsTer25 p.E115Rfs*25 ENST00000377577 NM_018198.3 115 GAa/a 0 +FAM48A UCSF GRCh37 13 37583915 37583915 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 48 10 60 0 ENST00000350612.6:c.2234T>C p.Met745Thr p.M745T ENST00000350612 NM_001014286.2 745 aTg/aCg 0 +GSDMD UCSF GRCh37 8 144641513 144641513 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 90 69 146 0 ENST00000526406.1:c.8C>T p.Ser3Leu p.S3L ENST00000526406 NM_001166237.1 3 tCg/tTg 0 +HIVEP2 UCSF GRCh37 6 143092015 143092015 + synonymous_variant Silent SNP C C G NOVEL P25_Pri Untested WXS Illumina HiSeq 435 310 810 0 ENST00000367603.2:c.3861G>C p.Gly1287= p.G1287= ENST00000367603 NM_006734.3 1287 ggG/ggC 0 +HOOK3 UCSF GRCh37 8 42819516 42819519 + frameshift_variant Frame_Shift_Del DEL ACTC ACTC - NOVEL P25_Pri Untested WXS Illumina HiSeq 217 0 ENST00000307602.4:c.679_682del p.Leu227IlefsTer6 p.L227Ifs*6 ENST00000307602 NM_032410.3 226 agACTC/ag 0 +HS6ST1 UCSF GRCh37 2 129075919 129075919 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0243,snp132_rs61732019 P25_Pri Untested WXS Illumina HiSeq 11 4 28 1 ENST00000259241.6:c.219C>T p.Arg73= p.R73= ENST00000259241 NM_004807.2 73 cgC/cgT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 20 19 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IFNAR2 UCSF GRCh37 21 34635055 34635084 + intron_variant Intron DEL ACAGCTGATACGGACTCTCTCTCTCTTTTT ACAGCTGATACGGACTCTCTCTCTCTTTTT TACAGCTGATATGGACTCTCTCTCTC NOVEL P25_Pri Untested WXS Illumina HiSeq 31 0 ENST00000342136.4:c.841-43_841-14delinsTACAGCTGATATGGACTCTCTCTCTC *281* ENST00000342136 0 +KIAA1524 UCSF GRCh37 3 108276093 108276093 + missense_variant Missense_Mutation SNP T T A NOVEL P25_Pri Untested WXS Illumina HiSeq 64 28 103 0 ENST00000295746.8:c.2182A>T p.Thr728Ser p.T728S ENST00000295746 NM_020890.2 728 Aca/Tca 0 +KRT75 UCSF GRCh37 12 52825420 52825420 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 129 87 202 0 ENST00000252245.5:c.777C>T p.Asp259= p.D259= ENST00000252245 NM_004693.2 259 gaC/gaT 0 +MFSD7 UCSF GRCh37 4 680052 680052 + missense_variant Missense_Mutation SNP G G C NOVEL P25_Pri Untested WXS Illumina HiSeq 60 26 58 0 ENST00000322224.4:c.334C>G p.Leu112Val p.L112V ENST00000322224 112 Cta/Gta 0 +MFSD7 UCSF GRCh37 4 679684 679684 + synonymous_variant Silent SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 316 136 294 0 ENST00000322224.4:c.525C>T p.Val175= p.V175= ENST00000322224 175 gtC/gtT 0 +MUC16 UCSF GRCh37 19 9065233 9065233 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 100 77 162 1 ENST00000397910.4:c.22213T>C p.Ser7405Pro p.S7405P ENST00000397910 NM_024690.2 7405 Tct/Cct 0 +NAGS UCSF GRCh37 17 42084844 42084844 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 81 42 72 0 ENST00000293404.3:c.1250C>T p.Ser417Phe p.S417F ENST00000293404 NM_153006.2 417 tCc/tTc 0 +NOTCH4 UCSF GRCh37 6 32169238 32169238 + synonymous_variant Silent SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 126 123 222 0 ENST00000375023.3:c.3795C>T p.Asn1265= p.N1265= ENST00000375023 NM_004557.3 1265 aaC/aaT 0 +NRXN1 UCSF GRCh37 2 50464102 50464102 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 116 40 176 0 ENST00000404971.1:c.3491C>T p.Thr1164Met p.T1164M ENST00000404971 NM_001135659.1 1164 aCg/aTg 0 +NSRP1 UCSF GRCh37 17 28506119 28506119 + missense_variant Missense_Mutation SNP T T G NOVEL P25_Pri Untested WXS Illumina HiSeq 8 7 9 0 ENST00000247026.5:c.312T>G p.Ile104Met p.I104M ENST00000247026 NM_032141.3 104 atT/atG 0 +NXF1 UCSF GRCh37 11 62564841 62564841 + synonymous_variant Silent SNP G G T NOVEL P25_Pri Untested WXS Illumina HiSeq 25 32 52 0 ENST00000532297.1:c.1071C>A p.Pro357= p.P357= ENST00000532297 357 ccC/ccA 0 +ODZ3 UCSF GRCh37 4 183574952 183574952 + missense_variant Missense_Mutation SNP G G C NOVEL P25_Pri Untested WXS Illumina HiSeq 209 128 384 0 ENST00000511685.1:c.1017G>C p.Gln339His p.Q339H ENST00000511685 339 caG/caC 0 +OGFR UCSF GRCh37 20 61441865 61441865 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 101 44 134 0 ENST00000290291.6:c.413G>A p.Arg138Gln p.R138Q ENST00000290291 NM_007346.2 138 cGa/cAa 0 +OR13C8 UCSF GRCh37 9 107332403 107332403 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 80 9 81 0 ENST00000335040.1:c.955G>A p.Gly319Arg p.G319R ENST00000335040 NM_001004483.1 319 Gga/Aga 0 +OR2M7 UCSF GRCh37 1 248487504 248487504 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 12 2 22 0 ENST00000317965.2:c.367T>C p.Tyr123His p.Y123H ENST00000317965 NM_001004691.1 123 Tac/Cac 0 +PCDHB7 UCSF GRCh37 5 140553940 140553940 + synonymous_variant Silent SNP G G A snp132_rs17844458 P25_Pri Untested WXS Illumina HiSeq 14 7 9 0 ENST00000231137.3:c.1524G>A p.Ala508= p.A508= ENST00000231137 NM_018940.2 508 gcG/gcA 0 +PDE6B UCSF GRCh37 4 659088 659088 + synonymous_variant Silent SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 61 31 75 0 ENST00000496514.1:c.2238G>A p.Leu746= p.L746= ENST00000496514 746 ttG/ttA 0 +PUS10 UCSF GRCh37 2 61181117 61181117 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Pri Untested WXS Illumina HiSeq 172 55 214 0 ENST00000316752.6:c.1141A>G p.Asn381Asp p.N381D ENST00000316752 NM_144709.2 381 Aat/Gat 0 +PYCR2 UCSF GRCh37 1 226108161 226108163 + inframe_deletion In_Frame_Del DEL CTT CTT - NOVEL P25_Pri Untested WXS Illumina HiSeq 7 0 ENST00000343818.6:c.955_957del p.Lys319del p.K319del ENST00000343818 NM_013328.3 319 AAG/- 0 +QRICH2 UCSF GRCh37 17 74288509 74288510 + inframe_insertion In_Frame_Ins INS - - CTGCACCAGGTTGGACCAAACCACGCTGAT NOVEL P25_Pri Untested WXS Illumina HiSeq 9 0 ENST00000262765.5:c.1800_1801insATCAGCGTGGTTTGGTCCAACCTGGTGCAG p.Ala600_Asp601insIleSerValValTrpSerAsnLeuValGln p.A600_D601insISVVWSNLVQ ENST00000262765 NM_032134.1 600 -/ATCAGCGTGGTTTGGTCCAACCTGGTGCAG 0 +RPS6KC1 UCSF GRCh37 1 213415490 213415492 + inframe_deletion In_Frame_Del DEL AAA AAA - NOVEL P25_Pri Untested WXS Illumina HiSeq 7 0 ENST00000366960.3:c.2674_2676del p.Lys892del p.K892del ENST00000366960 NM_012424.3 891 AAA/- 0 +SLC23A2 UCSF GRCh37 20 4850569 4850570 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P25_Pri Untested WXS Illumina HiSeq 13 0 ENST00000379333.1:c.1233dup p.Ile412HisfsTer18 p.I412Hfs*18 ENST00000379333 NM_203327.1 411 ccc/ccCc 0 +SLC9A1 UCSF GRCh37 1 27440317 27440317 + splice_region_variant,synonymous_variant Splice_Region SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 142 17 142 0 ENST00000263980.3:c.813G>A p.Val271= p.V271= ENST00000263980 NM_003047.4 271 gtG/gtA 0 +SPEN UCSF GRCh37 1 16257644 16257644 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 128 131 237 0 ENST00000375759.3:c.4909G>A p.Val1637Ile p.V1637I ENST00000375759 NM_015001.2 1637 Gtt/Att 0 +STXBP5 UCSF GRCh37 6 147648347 147648347 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 41 36 94 0 ENST00000321680.6:c.2015A>G p.Tyr672Cys p.Y672C ENST00000321680 NM_001127715.2 672 tAt/tGt 0 +TCF12 UCSF GRCh37 15 57524581 57524582 + frameshift_variant Frame_Shift_Del DEL AT AT - NOVEL P25_Pri Untested WXS Illumina HiSeq 13 0 ENST00000438423.2:c.778_779del p.Met260ValfsTer5 p.M260Vfs*5 ENST00000438423 NM_207037.1 260 ATg/g 0 +TEP1 UCSF GRCh37 14 20871601 20871601 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 148 26 131 0 ENST00000262715.5:c.1201G>A p.Glu401Lys p.E401K ENST00000262715 NM_007110.4 401 Gag/Aag 0 +THAP5 UCSF GRCh37 7 108205526 108205526 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P25_Pri Untested WXS Illumina HiSeq 10 0 ENST00000415914.3:c.297delA p.Lys99AsnfsTer25 p.K99Nfs*25 ENST00000415914 NM_001130475.1 99 aaA/aa 0 +TRPM1 UCSF GRCh37 15 31334362 31334362 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.012,1000g2011may_all_0.02529,snp132_rs17815774 P25_Pri Untested WXS Illumina HiSeq 91 49 186 0 ENST00000542188.1:c.1930G>A p.Val644Met p.V644M ENST00000542188 NM_001252020.1 644 Gtg/Atg 0 +VPS35 UCSF GRCh37 16 46706301 46706301 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Pri Untested WXS Illumina HiSeq 119 16 360 0 ENST00000299138.7:c.1244T>C p.Val415Ala p.V415A ENST00000299138 NM_018206.4 415 gTc/gCc 0 +YARS UCSF GRCh37 1 33245060 33245060 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Pri Untested WXS Illumina HiSeq 173 170 343 0 ENST00000373477.4:c.1399G>A p.Val467Met p.V467M ENST00000373477 NM_003680.3 467 Gtg/Atg 0 +YES1 UCSF GRCh37 18 756607 756607 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Pri Untested WXS Illumina HiSeq 75 47 138 0 ENST00000314574.4:c.221C>T p.Ala74Val p.A74V ENST00000314574 NM_005433.3 74 gCa/gTa 0 +ZNF761 UCSF GRCh37 19 53952869 53952869 + non_coding_transcript_exon_variant RNA SNP T T C NOVEL P25_Pri Untested WXS Illumina HiSeq 22 4 25 1 ENST00000454407.1:n.573T>C *191* ENST00000454407 0 +ZNF844 UCSF GRCh37 19 12186387 12186387 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Pri Untested WXS Illumina HiSeq 100 77 183 0 ENST00000439326.3:c.452G>T p.Arg151Ile p.R151I ENST00000439326 NM_001136501.1 151 aGa/aTa 0 +ADAM32 UCSF GRCh37 8 39007313 39007313 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 86 16 97 0 ENST00000379907.4:c.280C>G p.Gln94Glu p.Q94E ENST00000379907 NM_145004.5 94 Caa/Gaa 0 +ALB UCSF GRCh37 4 74280766 74280766 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 68 51 156 0 ENST00000295897.4:c.1073A>G p.Tyr358Cys p.Y358C ENST00000295897 NM_000477.5 358 tAt/tGt 0 +ALG8 UCSF GRCh37 11 77832193 77832193 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000299626.5:c.396delA p.Val133TrpfsTer24 p.V133Wfs*24 ENST00000299626 NM_024079.4 132 aaA/aa 0 +ALG8 UCSF GRCh37 11 77824924 77824971 + splice_donor_variant,coding_sequence_variant,intron_variant Splice_Site DEL AGGCTTACCAAGGCCAGGAAAGGACCCAATGAAAGAGCAGAAACTAAG AGGCTTACCAAGGCCAGGAAAGGACCCAATGAAAGAGCAGAAACTAAG GGCTTACCAAGGCCAGGAAAGGACCCAATGAAAGAGCAAAAACAAAA NOVEL P25_Rec Untested WXS Illumina HiSeq 11 0 ENST00000299626.5:c.738_777+8delinsTTTTGTTTTTGCTCTTTCATTGGGTCCTTTCCTGGCCTTGGTAAGCC p.X246_splice ENST00000299626 NM_024079.4 246 0 +ATRX UCSF GRCh37 X 76918873 76918874 + frameshift_variant,splice_region_variant Frame_Shift_Del DEL TT TT - NOVEL P25_Rec Untested WXS Illumina HiSeq 33 0 ENST00000373344.5:c.4117_4118del p.Lys1373GlyfsTer4 p.K1373Gfs*4 ENST00000373344 NM_000489.3 1373 AAg/g 0 +BAI3 UCSF GRCh37 6 69943256 69943257 + frameshift_variant Frame_Shift_Del DEL TA TA - NOVEL P25_Rec Untested WXS Illumina HiSeq 106 0 ENST00000370598.1:c.2556_2557del p.Cys853Ter p.C853* ENST00000370598 NM_001704.2 852 tTA/t 0 +BMPR2 UCSF GRCh37 2 203383749 203383752 + frameshift_variant Frame_Shift_Del DEL TTGC TTGC - NOVEL P25_Rec Untested WXS Illumina HiSeq 79 0 ENST00000374580.4:c.829_832del p.Leu277Ter p.L277* ENST00000374580 NM_001204.6 276 TTGCtt/tt 0 +CACNA1H UCSF GRCh37 16 1270131 1270131 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 252 28 285 0 ENST00000348261.5:c.6199G>A p.Val2067Ile p.V2067I ENST00000348261 NM_021098.2 2067 Gtc/Atc 0 +CCDC114 UCSF GRCh37 19 48800560 48800561 + frameshift_variant Frame_Shift_Del DEL AA AA - NOVEL P25_Rec Untested WXS Illumina HiSeq 57 0 ENST00000315396.7:c.1685_1686del p.Phe562TrpfsTer18 p.F562Wfs*18 ENST00000315396 NM_144577.3 562 tTT/t 0 +CCNA1 UCSF GRCh37 13 37007335 37007335 + stop_gained Nonsense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 41 13 110 0 ENST00000255465.4:c.274C>T p.Gln92Ter p.Q92* ENST00000255465 92 Cag/Tag 0 +CCNB1 UCSF GRCh37 5 68464167 68464167 + synonymous_variant Silent SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 157 40 189 0 ENST00000256442.5:c.360T>C p.Ile120= p.I120= ENST00000256442 NM_031966.3 120 atT/atC 0 +CCND1 UCSF GRCh37 11 69458623 69458623 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec somatic WXS Sanger Illumina HiSeq 544 420 87 0 ENST00000227507.2:c.438C>G p.Asn146Lys p.N146K ENST00000227507 NM_053056.2 146 aaC/aaG 0 +CD93 UCSF GRCh37 20 23065795 23065795 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 137 77 299 0 ENST00000246006.4:c.1035C>T p.Asp345= p.D345= ENST00000246006 NM_012072.3 345 gaC/gaT 0 +CDH17 UCSF GRCh37 8 95201472 95201472 + synonymous_variant Silent SNP C C A NOVEL P25_Rec Untested WXS Illumina HiSeq 200 108 293 1 ENST00000027335.3:c.93G>T p.Leu31= p.L31= ENST00000027335 NM_004063.3 31 ctG/ctT 0 +CLSPN UCSF GRCh37 1 36215290 36215290 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 106 25 142 0 ENST00000318121.3:c.2151G>C p.Lys717Asn p.K717N ENST00000318121 NM_022111.3 717 aaG/aaC 0 +CNGA3 UCSF GRCh37 2 99013128 99013128 + stop_gained Nonsense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 86 13 109 0 ENST00000393504.1:c.1495C>T p.Arg499Ter p.R499* ENST00000393504 NM_001298.2 499 Cga/Tga 0 +CNTLN UCSF GRCh37 9 17462971 17462973 + inframe_deletion In_Frame_Del DEL CTC CTC - NOVEL P25_Rec Untested WXS Illumina HiSeq 43 0 ENST00000380647.3:c.3366_3368del p.Leu1123del p.L1123del ENST00000380647 1122 CTC/- 0 +COL17A1 UCSF GRCh37 10 105815696 105815696 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 38 191 362 0 ENST00000353479.5:c.1531C>T p.Pro511Ser p.P511S ENST00000353479 NM_000494.3 511 Ccc/Tcc 0 +COL4A4 UCSF GRCh37 2 227920746 227920746 + synonymous_variant Silent SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 80 28 150 0 ENST00000396625.3:c.2631G>A p.Arg877= p.R877= ENST00000396625 NM_000092.4 877 cgG/cgA 0 +COL4A5 UCSF GRCh37 X 107846253 107846253 + stop_gained Nonsense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 59 42 103 0 ENST00000328300.6:c.2206G>T p.Glu736Ter p.E736* ENST00000328300 NM_033380.2 736 Gaa/Taa 0 +COL5A1 UCSF GRCh37 9 137703350 137703350 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 342 38 393 1 ENST00000371817.3:c.3595G>A p.Glu1199Lys p.E1199K ENST00000371817 NM_001278074.1 1199 Gag/Aag 0 +CPEB1 UCSF GRCh37 15 83226697 83226697 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 86 68 171 0 ENST00000568128.1:c.419G>A p.Gly140Glu p.G140E ENST00000568128 NM_030594.3 140 gGa/gAa 0 +DDX28 UCSF GRCh37 16 68055853 68055853 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 305 230 440 0 ENST00000332395.5:c.1253A>G p.Asp418Gly p.D418G ENST00000332395 NM_018380.3 418 gAt/gGt 0 +DNAJC21 UCSF GRCh37 5 34950377 34950377 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 57 12 79 0 ENST00000382021.2:c.1423A>G p.Ser475Gly p.S475G ENST00000382021 NM_194283.3 475 Agt/Ggt 0 +ESM1 UCSF GRCh37 5 54275251 54275252 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P25_Rec Untested WXS Illumina HiSeq 177 0 ENST00000381405.4:c.464dup p.Ser156IlefsTer66 p.S156Ifs*66 ENST00000381405 NM_007036.4 155 gca/gCca 0 +FAM169B UCSF GRCh37 15 98995135 98995135 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 61 14 86 0 ENST00000558256.1:c.289C>A p.Leu97Met p.L97M ENST00000558256 NM_182562.2 97 Ctg/Atg 0 +FAM47C UCSF GRCh37 X 37027335 37027335 + synonymous_variant Silent SNP A A T NOVEL P25_Rec Untested WXS Illumina HiSeq 68 50 123 0 ENST00000358047.3:c.852A>T p.Pro284= p.P284= ENST00000358047 NM_001013736.2 284 ccA/ccT 0 +FSIP2 UCSF GRCh37 2 186697826 186697826 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 104 71 223 0 ENST00000343098.5:c.20864A>G p.Lys6955Arg p.K6955R ENST00000343098 NM_173651.2 6955 aAg/aGg 0 +GNAS UCSF GRCh37 20 57429313 57429313 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 303 47 311 0 ENST00000371100.4:c.993G>A p.Ala331= p.A331= ENST00000371100 NM_001077490.1 331 gcG/gcA 0 +GSDMD UCSF GRCh37 8 144641513 144641513 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 94 103 146 0 ENST00000526406.1:c.8C>T p.Ser3Leu p.S3L ENST00000526406 NM_001166237.1 3 tCg/tTg 0 +HIVEP2 UCSF GRCh37 6 143092015 143092015 + synonymous_variant Silent SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 285 241 810 0 ENST00000367603.2:c.3861G>C p.Gly1287= p.G1287= ENST00000367603 NM_006734.3 1287 ggG/ggC 0 +HMG20A UCSF GRCh37 15 77770709 77770709 + missense_variant Missense_Mutation SNP A A T NOVEL P25_Rec Untested WXS Illumina HiSeq 129 17 106 0 ENST00000381714.3:c.764A>T p.Lys255Met p.K255M ENST00000381714 NM_018200.2 255 aAg/aTg 0 +HMG20B UCSF GRCh37 19 3576984 3576984 + synonymous_variant Silent SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 64 19 82 0 ENST00000333651.6:c.687C>T p.Ser229= p.S229= ENST00000333651 NM_006339.2 229 agC/agT 0 +HRASLS2 UCSF GRCh37 11 63320450 63320450 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.001,1000g2011may_all_0.0030 P25_Rec Untested WXS Illumina HiSeq 163 23 377 0 ENST00000255695.1:c.475C>T p.Arg159Trp p.R159W ENST00000255695 NM_017878.1 159 Cgg/Tgg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 8 8 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL7R UCSF GRCh37 5 35875666 35875666 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 98 24 134 0 ENST00000303115.3:c.853C>T p.His285Tyr p.H285Y ENST00000303115 NM_002185.3 285 Cat/Tat 0 +INHBA UCSF GRCh37 7 41729606 41729606 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 345 103 528 0 ENST00000242208.4:c.923G>A p.Arg308His p.R308H ENST00000242208 NM_002192.2 308 cGt/cAt 0 +INTS4 UCSF GRCh37 11 77672161 77672189 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region INS ACCATGAGACGTATCTGTCAGATGCTATT ACCATGAGACGTATCTGTCAGATGCTATT CCCAAGAGACGTATCTTTCAAATGCTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 7 0 ENST00000534064.1:c.472-5_495delinsTAATAGCATTTGAAAGATACGTCTCTTGGG p.X158_splice ENST00000534064 NM_033547.3 0 +INTS4 UCSF GRCh37 11 77672148 77672189 + splice_region_variant,coding_sequence_variant,intron_variant Splice_Region INS ACTTATTTCTTACACCATGAGACGTATCTGTCAGATGCTATT ACTTATTTCTTACACCATGAGACGTATCTGTCAGATGCTATT CCTTTTTTTTTTCACCATGAGACGTATTTTTCAGAAGCTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 9 0 ENST00000534064.1:c.472-5_508delinsTAATAGCTTCTGAAAAATACGTCTCATGGTGAAAAAAAAAAGG p.X158_splice ENST00000534064 NM_033547.3 0 +INTS4 UCSF GRCh37 11 77672152 77672189 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS ATTTCTTACACCATGAGACGTATCTGTCAGATGCTATT ATTTCTTACACCATGAGACGTATCTGTCAGATGCTATT TTTTTTTTCACCATAAGACGTATCTTTCAAATGTTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 17 0 ENST00000534064.1:c.472-5_504delinsTAATAACATTTGAAAGATACGTCTTATGGTGAAAAAAAA p.X158_splice ENST00000534064 NM_033547.3 0 +INTS4 UCSF GRCh37 11 77672175 77672189 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS CTGTCAGATGCTATT CTGTCAGATGCTATT ATTTCAGATGTTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 7 0 ENST00000534064.1:c.472-5_481delinsTAATAACATCTGAAAT p.X158_splice ENST00000534064 NM_033547.3 0 +INTS4 UCSF GRCh37 11 77672165 77672189 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site INS TGAGACGTATCTGTCAGATGCTATT TGAGACGTATCTGTCAGATGCTATT AGAAAAGTTTTTTTAAAAAGTTATTA NOVEL P25_Rec Untested WXS Illumina HiSeq 7 0 ENST00000534064.1:c.472-5_491delinsTAATAACTTTTTAAAAAAACTTTTCT p.X158_splice ENST00000534064 NM_033547.3 0 +ITGA2 UCSF GRCh37 5 52385787 52385787 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 220 27 231 0 ENST00000296585.5:c.3360G>A p.Met1120Ile p.M1120I ENST00000296585 NM_002203.3 1120 atG/atA 0 +KLHDC4 UCSF GRCh37 16 87744934 87744934 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 318 38 355 0 ENST00000270583.5:c.951C>T p.Asp317= p.D317= ENST00000270583 NM_017566.3 317 gaC/gaT 0 +KRT75 UCSF GRCh37 12 52825420 52825420 + splice_region_variant,synonymous_variant Splice_Region SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 116 91 202 0 ENST00000252245.5:c.777C>T p.Asp259= p.D259= ENST00000252245 NM_004693.2 259 gaC/gaT 0 +KRT82 UCSF GRCh37 12 52793852 52793852 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.010,1000g2011may_all_0.0015,snp132_rs61730589 P25_Rec Untested WXS Illumina HiSeq 86 20 97 0 ENST00000257974.2:c.859G>A p.Gly287Ser p.G287S ENST00000257974 NM_033033.3 287 Ggc/Agc 0 +LLGL2 UCSF GRCh37 17 73569328 73569328 + synonymous_variant Silent SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 78 23 59 0 ENST00000392550.3:c.2694C>T p.Ile898= p.I898= ENST00000392550 NM_001031803.1 898 atC/atT 0 +LONRF1 UCSF GRCh37 8 12612285 12612285 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 25 30 76 0 ENST00000398246.3:c.645C>T p.Ala215= p.A215= ENST00000398246 NM_152271.3 215 gcC/gcT 0 +MARS UCSF GRCh37 12 57883053 57883053 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P25_Rec Untested WXS Illumina HiSeq 13 0 ENST00000262027.5:c.212del p.Leu71CysfsTer33 p.L71Cfs*33 ENST00000262027 NM_004990.3 68 taT/ta 0 +MARS UCSF GRCh37 12 57882776 57882808 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TAACCCATTTTCCATTCTTGCATCAGATTGTGT TAACCCATTTTCCATTCTTGCATCAGATTGTGT AACCCATTTTCCATTCTTGCATCAGATTTTGG NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000262027.5:c.110-26_116delinsAACCCATTTTCCATTCTTGCATCAGATTTTGG p.X37_splice ENST00000262027 NM_004990.3 0 +MFSD7 UCSF GRCh37 4 680052 680052 + missense_variant Missense_Mutation SNP G G C NOVEL P25_Rec Untested WXS Illumina HiSeq 72 17 58 0 ENST00000322224.4:c.334C>G p.Leu112Val p.L112V ENST00000322224 112 Cta/Gta 0 +MFSD7 UCSF GRCh37 4 679684 679684 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 458 120 294 0 ENST00000322224.4:c.525C>T p.Val175= p.V175= ENST00000322224 175 gtC/gtT 0 +MORC4 UCSF GRCh37 X 106185751 106185751 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 129 99 218 0 ENST00000355610.4:c.2370G>C p.Gln790His p.Q790H ENST00000355610 NM_001085354.2 790 caG/caC 0 +MUC16 UCSF GRCh37 19 9065233 9065233 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 99 72 162 1 ENST00000397910.4:c.22213T>C p.Ser7405Pro p.S7405P ENST00000397910 NM_024690.2 7405 Tct/Cct 0 +MYCN UCSF GRCh37 2 16082314 16082315 + frameshift_variant Frame_Shift_Ins INS - - C NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000281043.3:c.134dup p.Glu47GlyfsTer8 p.E47Gfs*8 ENST00000281043 NM_005378.4 43 acc/acCc 0 +MYEOV UCSF GRCh37 11 69063724 69063724 + frameshift_variant Frame_Shift_Del DEL G G - 1000g2010nov_all P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000308946.3:c.813delG p.Trp272GlyfsTer66 p.W272Gfs*66 ENST00000308946 NM_138768.2 269 ctG/ct 0 +MYH14 UCSF GRCh37 19 50780049 50780049 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 57 11 67 0 ENST00000601313.1:c.3716A>G p.Lys1239Arg p.K1239R ENST00000601313 NM_001145809.1 1239 aAg/aGg 0 +NAGS UCSF GRCh37 17 42084844 42084844 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 84 39 72 0 ENST00000293404.3:c.1250C>T p.Ser417Phe p.S417F ENST00000293404 NM_153006.2 417 tCc/tTc 0 +NBPF1 UCSF GRCh37 1 16893721 16893721 + missense_variant Missense_Mutation SNP A A C 1000g2010nov_all_0.064 P25_Rec Untested WXS Illumina HiSeq 10 5 13 0 ENST00000430580.2:c.2792T>G p.Phe931Cys p.F931C ENST00000430580 NM_017940.4 931 tTt/tGt 0 +NLRP9 UCSF GRCh37 19 56243414 56243414 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 50 39 118 0 ENST00000332836.2:c.1783C>T p.Arg595Cys p.R595C ENST00000332836 NM_176820.2 595 Cgc/Tgc 0 +NOTCH4 UCSF GRCh37 6 32169238 32169238 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 235 106 222 0 ENST00000375023.3:c.3795C>T p.Asn1265= p.N1265= ENST00000375023 NM_004557.3 1265 aaC/aaT 0 +NRP2 UCSF GRCh37 2 206605343 206605345 + inframe_deletion In_Frame_Del DEL CAG CAG - NOVEL P25_Rec Untested WXS Illumina HiSeq 10 0 ENST00000360409.3:c.1247_1249del p.Ser416_Gly417delinsCys p.S416_G417delinsC ENST00000360409 NM_003872.2 416 tCAGgt/tgt 0 +NXF1 UCSF GRCh37 11 62564841 62564841 + synonymous_variant Silent SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 7 31 52 0 ENST00000532297.1:c.1071C>A p.Pro357= p.P357= ENST00000532297 357 ccC/ccA 0 +OGFR UCSF GRCh37 20 61441865 61441865 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 97 74 134 0 ENST00000290291.6:c.413G>A p.Arg138Gln p.R138Q ENST00000290291 NM_007346.2 138 cGa/cAa 0 +OR2A5 UCSF GRCh37 7 143747979 143747979 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 132 56 285 0 ENST00000408906.2:c.485T>C p.Leu162Pro p.L162P ENST00000408906 NM_012365.1 162 cTc/cCc 0 +OR4S2 UCSF GRCh37 11 55419231 55419231 + synonymous_variant Silent SNP T T A NOVEL P25_Rec Untested WXS Illumina HiSeq 71 55 285 0 ENST00000312422.2:c.852T>A p.Ile284= p.I284= ENST00000312422 NM_001004059.2 284 atT/atA 0 +OR52A5 UCSF GRCh37 11 5153593 5153593 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 177 149 573 0 ENST00000307388.1:c.280A>G p.Ile94Val p.I94V ENST00000307388 NM_001005160.2 94 Att/Gtt 0 +OR6C6 UCSF GRCh37 12 55688653 55688653 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 148 33 196 0 ENST00000358433.2:c.364G>A p.Val122Ile p.V122I ENST00000358433 NM_001005493.1 122 Gtt/Att 0 +PDE6B UCSF GRCh37 4 659088 659088 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 96 22 75 0 ENST00000496514.1:c.2238G>A p.Leu746= p.L746= ENST00000496514 746 ttG/ttA 0 +PGLYRP3 UCSF GRCh37 1 153279615 153279615 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 79 26 81 0 ENST00000290722.1:c.184G>A p.Val62Ile p.V62I ENST00000290722 NM_052891.1 62 Gtt/Att 0 +PGR UCSF GRCh37 11 100996839 100996839 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 48 24 176 0 ENST00000325455.5:c.1688C>T p.Pro563Leu p.P563L ENST00000325455 NM_001202474.3 563 cCt/cTt 0 +PIGR UCSF GRCh37 1 207105892 207105892 + synonymous_variant Silent SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 59 26 107 0 ENST00000356495.4:c.1917G>A p.Ala639= p.A639= ENST00000356495 NM_002644.3 639 gcG/gcA 0 +PLA2G4A UCSF GRCh37 1 186909194 186909194 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 364 113 469 0 ENST00000367466.3:c.1001T>C p.Val334Ala p.V334A ENST00000367466 NM_024420.2 334 gTc/gCc 0 +PLEKHG1 UCSF GRCh37 6 151161729 151161731 + inframe_deletion In_Frame_Del DEL AGA AGA - NOVEL P25_Rec Untested WXS Illumina HiSeq 47 0 ENST00000367328.1:c.3861_3863del p.Glu1287del p.E1287del ENST00000367328 NM_001029884.1 1285 tcAGAa/tca 0 +PLEKHG6 UCSF GRCh37 12 6436644 6436644 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 68 46 96 0 ENST00000396988.3:c.1895G>A p.Arg632His p.R632H ENST00000396988 NM_001144856.1 632 cGt/cAt 0 +PRSS21 UCSF GRCh37 16 2867889 2867889 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 46 6 47 0 ENST00000005995.3:c.179G>A p.Arg60His p.R60H ENST00000005995 60 cGc/cAc 0 +QRICH2 UCSF GRCh37 17 74288509 74288510 + inframe_insertion In_Frame_Ins INS - - CTGCACCAGGTTGGACCAAACCACGCTGAT NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000262765.5:c.1800_1801insATCAGCGTGGTTTGGTCCAACCTGGTGCAG p.Ala600_Asp601insIleSerValValTrpSerAsnLeuValGln p.A600_D601insISVVWSNLVQ ENST00000262765 NM_032134.1 600 -/ATCAGCGTGGTTTGGTCCAACCTGGTGCAG 0 +RPH3A UCSF GRCh37 12 113314503 113314503 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 63 11 69 0 ENST00000389385.4:c.1003G>A p.Gly335Arg p.G335R ENST00000389385 NM_001143854.1 335 Gga/Aga 0 +SCAND3 UCSF GRCh37 6 28543477 28543477 + missense_variant Missense_Mutation SNP C C A NOVEL P25_Rec Untested WXS Illumina HiSeq 499 78 490 0 ENST00000452236.2:c.1005G>T p.Lys335Asn p.K335N ENST00000452236 NM_052923.1 335 aaG/aaT 0 +SEC63 UCSF GRCh37 6 108214774 108214774 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000369002.4:c.1586del p.Lys529ArgfsTer4 p.K529Rfs*4 ENST00000369002 NM_007214.4 529 aAg/ag 0 +SEMA3B UCSF GRCh37 3 50310793 50310795 + intron_variant,non_coding_transcript_variant Intron DEL CTT CTT - NOVEL P25_Rec Untested WXS Illumina HiSeq 84 0 ENST00000456210.1:n.158+54_158+56delCTT *53* ENST00000456210 0 +SEMA6D UCSF GRCh37 15 48058784 48058784 + intron_variant Intron SNP G G C NOVEL P25_Rec Untested WXS Illumina HiSeq 128 30 174 0 ENST00000316364.5:c.1647-29G>C *549* ENST00000316364 NM_153618.1 0 +SIN3B UCSF GRCh37 19 16976309 16976311 + inframe_deletion In_Frame_Del DEL AGG AGG - NOVEL P25_Rec Untested WXS Illumina HiSeq 9 0 ENST00000379803.1:c.1570_1572del p.Glu524del p.E524del ENST00000379803 NM_015260.2 523 cAGGag/cag 0 +SLC23A2 UCSF GRCh37 20 4850569 4850570 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P25_Rec Untested WXS Illumina HiSeq 13 0 ENST00000379333.1:c.1233dup p.Ile412HisfsTer18 p.I412Hfs*18 ENST00000379333 NM_203327.1 411 ccc/ccCc 0 +SLC26A9 UCSF GRCh37 1 205899074 205899074 + missense_variant Missense_Mutation SNP C C G NOVEL P25_Rec Untested WXS Illumina HiSeq 59 14 80 0 ENST00000367134.2:c.663G>C p.Lys221Asn p.K221N ENST00000367134 NM_134325.2 221 aaG/aaC 0 +SLC6A3 UCSF GRCh37 5 1422076 1422076 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 122 28 141 0 ENST00000270349.9:c.707C>T p.Pro236Leu p.P236L ENST00000270349 NM_001044.4 236 cCg/cTg 0 +SLIT3 UCSF GRCh37 5 168093656 168093656 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 46 40 154 0 ENST00000519560.1:c.4375C>T p.Arg1459Cys p.R1459C ENST00000519560 NM_003062.3 1459 Cgc/Tgc 0 +SPATS2L UCSF GRCh37 2 201303884 201303884 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 147 52 216 0 ENST00000358677.5:c.485G>A p.Gly162Glu p.G162E ENST00000358677 NM_015535.2 162 gGg/gAg 0 +SPEN UCSF GRCh37 1 16257644 16257644 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 258 134 237 0 ENST00000375759.3:c.4909G>A p.Val1637Ile p.V1637I ENST00000375759 NM_015001.2 1637 Gtt/Att 0 +STXBP5 UCSF GRCh37 6 147648347 147648347 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 34 18 94 0 ENST00000321680.6:c.2015A>G p.Tyr672Cys p.Y672C ENST00000321680 NM_001127715.2 672 tAt/tGt 0 +TGM3 UCSF GRCh37 20 2312794 2312794 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 119 51 228 0 ENST00000381458.5:c.1480G>T p.Ala494Ser p.A494S ENST00000381458 NM_003245.3 494 Gca/Tca 0 +TRPV5 UCSF GRCh37 7 142606703 142606703 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 23 6 47 0 ENST00000265310.1:c.1848C>T p.Ser616= p.S616= ENST00000265310 NM_019841.4 616 tcC/tcT 0 +UACA UCSF GRCh37 15 70959163 70959163 + missense_variant Missense_Mutation SNP T T C NOVEL P25_Rec Untested WXS Illumina HiSeq 334 46 424 1 ENST00000322954.6:c.3860A>G p.Lys1287Arg p.K1287R ENST00000322954 NM_018003.2 1287 aAg/aGg 0 +USP35 UCSF GRCh37 11 77920720 77920722 + inframe_deletion In_Frame_Del DEL CGC CGC - NOVEL P25_Rec Untested WXS Illumina HiSeq 6 0 ENST00000529308.1:c.1829_1831del p.Arg610del p.R610del ENST00000529308 NM_020798.2 607 CGC/- 0 +VPS35 UCSF GRCh37 16 46706301 46706301 + missense_variant Missense_Mutation SNP A A G NOVEL P25_Rec Untested WXS Illumina HiSeq 227 195 360 0 ENST00000299138.7:c.1244T>C p.Val415Ala p.V415A ENST00000299138 NM_018206.4 415 gTc/gCc 0 +WDR49 UCSF GRCh37 3 167249025 167249025 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 63 12 105 0 ENST00000308378.3:c.1040C>A p.Pro347His p.P347H ENST00000308378 NM_178824.3 347 cCc/cAc 0 +WIF1 UCSF GRCh37 12 65514908 65514908 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 15 3 25 0 ENST00000286574.4:c.64C>A p.Leu22Met p.L22M ENST00000286574 NM_007191.4 22 Ctg/Atg 0 +WRAP53 UCSF GRCh37 17 7592209 7592210 + frameshift_variant Frame_Shift_Del DEL AG AG - NOVEL P25_Rec Untested WXS Illumina HiSeq 70 0 ENST00000316024.5:c.245_246del p.Glu82ValfsTer5 p.E82Vfs*5 ENST00000316024 81 acAGag/acag 0 +YARS UCSF GRCh37 1 33245060 33245060 + missense_variant Missense_Mutation SNP C C T NOVEL P25_Rec Untested WXS Illumina HiSeq 293 159 343 0 ENST00000373477.4:c.1399G>A p.Val467Met p.V467M ENST00000373477 NM_003680.3 467 Gtg/Atg 0 +YES1 UCSF GRCh37 18 756607 756607 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 86 73 138 0 ENST00000314574.4:c.221C>T p.Ala74Val p.A74V ENST00000314574 NM_005433.3 74 gCa/gTa 0 +ZDBF2 UCSF GRCh37 2 207176038 207176038 + synonymous_variant Silent SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 150 50 243 0 ENST00000374423.3:c.6786G>A p.Ala2262= p.A2262= ENST00000374423 NM_020923.1 2262 gcG/gcA 0 +ZMYM6 UCSF GRCh37 1 35496163 35496165 + inframe_deletion In_Frame_Del DEL TTC TTC - NOVEL P25_Rec Untested WXS Illumina HiSeq 22 0 ENST00000357182.4:c.76_78del p.Glu26del p.E26del ENST00000357182 NM_007167.3 26 GAA/- 0 +ZNF202 UCSF GRCh37 11 123596991 123596991 + missense_variant Missense_Mutation SNP G G A NOVEL P25_Rec Untested WXS Illumina HiSeq 256 38 512 0 ENST00000336139.4:c.1661C>T p.Ala554Val p.A554V ENST00000336139 554 gCg/gTg 0 +ZNF208 UCSF GRCh37 19 22157024 22157024 + missense_variant Missense_Mutation SNP A A T NOVEL P25_Rec Untested WXS Illumina HiSeq 24 6 23 0 ENST00000397126.4:c.812T>A p.Ile271Asn p.I271N ENST00000397126 NM_007153.3 271 aTc/aAc 0 +ZNF844 UCSF GRCh37 19 12186387 12186387 + missense_variant Missense_Mutation SNP G G T NOVEL P25_Rec Untested WXS Illumina HiSeq 116 94 183 0 ENST00000439326.3:c.452G>T p.Arg151Ile p.R151I ENST00000439326 NM_001136501.1 151 aGa/aTa 0 +ZNF90 UCSF GRCh37 19 20228765 20228765 + missense_variant Missense_Mutation SNP C C A NOVEL P25_Rec Untested WXS Illumina HiSeq 154 41 222 0 ENST00000418063.2:c.402C>A p.Asn134Lys p.N134K ENST00000418063 NM_007138.1 134 aaC/aaA 0 +ANK3 UCSF GRCh37 10 61946630 61946630 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 42 29 101 0 ENST00000280772.2:c.1928A>G p.Gln643Arg p.Q643R ENST00000280772 NM_020987.3 643 cAg/cGg 0 +ANKRD30B UCSF GRCh37 18 14851953 14851953 + missense_variant Missense_Mutation SNP A A T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 33 5 56 0 ENST00000358984.4:c.3653A>T p.Asp1218Val p.D1218V ENST00000358984 NM_001145029.1 1218 gAt/gTt 0 +ATRX UCSF GRCh37 X 76909677 76909681 + frameshift_variant Frame_Shift_Del DEL CTTTC CTTTC - NOVEL P26_Pri_A Untested WXS Illumina HiSeq 73 0 ENST00000373344.5:c.4224_4228del p.Lys1408AsnfsTer11 p.K1408Nfs*11 ENST00000373344 NM_000489.3 1408 aaGAAAGca/aaca 0 +CHD4 UCSF GRCh37 12 6692539 6692539 + synonymous_variant Silent SNP T T C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 27 28 49 0 ENST00000357008.2:c.3885A>G p.Glu1295= p.E1295= ENST00000357008 NM_001273.2 1295 gaA/gaG 0 +EMR3 UCSF GRCh37 19 14748981 14748981 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 98 57 163 0 ENST00000253673.5:c.1420G>A p.Val474Ile p.V474I ENST00000253673 NM_032571.3 474 Gtt/Att 0 +EYS UCSF GRCh37 6 66112482 66112482 + missense_variant Missense_Mutation SNP C C G NOVEL P26_Pri_A Untested WXS Illumina HiSeq 84 54 138 0 ENST00000503581.1:c.1073G>C p.Cys358Ser p.C358S ENST00000503581 NM_001142800.1 358 tGt/tCt 0 +FGFR4 UCSF GRCh37 5 176522719 176522719 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 29 20 36 0 ENST00000292408.4:c.1816C>T p.Arg606Trp p.R606W ENST00000292408 NM_213647.1 606 Cgg/Tgg 0 +GAD1 UCSF GRCh37 2 171700560 171700565 + inframe_deletion In_Frame_Del DEL CATATG CATATG - NOVEL P26_Pri_A Untested WXS Illumina HiSeq 73 0 ENST00000358196.3:c.644_649del p.Thr215_Glu217delinsLys p.T215_E217delinsK ENST00000358196 NM_000817.2 215 aCATATGaa/aaa 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 13 16 27 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGHMBP2 UCSF GRCh37 11 68707014 68707014 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 8 12 25 0 ENST00000255078.3:c.2797G>A p.Gly933Ser p.G933S ENST00000255078 NM_002180.2 933 Ggt/Agt 0 +KIF26B UCSF GRCh37 1 245848890 245848890 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 91 66 164 0 ENST00000407071.2:c.2605G>A p.Gly869Arg p.G869R ENST00000407071 NM_018012.3 869 Ggg/Agg 0 +MED12 UCSF GRCh37 X 70357661 70357661 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 164 117 283 0 ENST00000374080.3:c.5912A>C p.Gln1971Pro p.Q1971P ENST00000374080 1971 cAg/cCg 0 +MURC UCSF GRCh37 9 103348678 103348678 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Pri_A Untested WXS Illumina HiSeq 190 49 156 0 ENST00000307584.5:c.1040A>G p.Gln347Arg p.Q347R ENST00000307584 NM_001018116.2 347 cAg/cGg 0 +NCOA6 UCSF GRCh37 20 33338237 33338237 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 43 43 94 0 ENST00000374796.2:c.1761T>G p.Ile587Met p.I587M ENST00000374796 587 atT/atG 0 +PCDHB2 UCSF GRCh37 5 140475862 140475862 + synonymous_variant Silent SNP G G A 1000g2011may_all_0.0149,snp132_rs61745643 P26_Pri_A Untested WXS Illumina HiSeq 22 4 28 1 ENST00000194155.4:c.1488G>A p.Gln496= p.Q496= ENST00000194155 NM_018936.2 496 caG/caA 0 +PGGT1B UCSF GRCh37 5 114552629 114552629 + missense_variant Missense_Mutation SNP T T A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 14 17 25 0 ENST00000419445.1:c.885A>T p.Arg295Ser p.R295S ENST00000419445 NM_005023.3 295 agA/agT 0 +RBMX UCSF GRCh37 X 135958696 135958696 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.08188,snp132_rs112800567 P26_Pri_A Untested WXS Illumina HiSeq 19 6 20 1 ENST00000320676.7:c.507A>G p.Gly169= p.G169= ENST00000320676 NM_002139.3 169 ggA/ggG 0 +RELN UCSF GRCh37 7 103138574 103138574 + synonymous_variant Silent SNP T T G NOVEL P26_Pri_A Untested WXS Illumina HiSeq 114 38 153 0 ENST00000428762.1:c.8793A>C p.Gly2931= p.G2931= ENST00000428762 NM_005045.3 2931 ggA/ggC 0 +RETSAT UCSF GRCh37 2 85570849 85570849 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.169,snp132_rs28418594 P26_Pri_A Untested WXS Illumina HiSeq 12 4 17 0 ENST00000295802.4:c.1606G>A p.Gly536Arg p.G536R ENST00000295802 NM_017750.3 536 Ggg/Agg 0 +SCN9A UCSF GRCh37 2 167056179 167056179 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Pri_A Untested WXS Illumina HiSeq 49 35 92 0 ENST00000409672.1:c.4937T>C p.Ile1646Thr p.I1646T ENST00000409672 NM_002977.3 1646 aTc/aCc 0 +SFI1 UCSF GRCh37 22 32014359 32014359 + synonymous_variant Silent SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 39 43 70 0 ENST00000400288.2:c.3684C>T p.Gly1228= p.G1228= ENST00000400288 NM_001007467.2 1228 ggC/ggT 0 +SLC38A8 UCSF GRCh37 16 84050190 84050190 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 28 26 43 1 ENST00000299709.3:c.1096C>T p.Pro366Ser p.P366S ENST00000299709 NM_001080442.1 366 Cct/Tct 0 +SPP1 UCSF GRCh37 4 88903874 88903875 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P26_Pri_A Untested WXS Illumina HiSeq 73 0 ENST00000395080.3:c.771_772del p.Ser258ArgfsTer4 p.S258Rfs*4 ENST00000395080 NM_001040058.1 257 caTTcc/cacc 0 +TBC1D5 UCSF GRCh37 3 17279718 17279718 + stop_gained Nonsense_Mutation SNP G G A NOVEL P26_Pri_A Untested WXS Illumina HiSeq 189 134 261 0 ENST00000446818.2:c.1525C>T p.Gln509Ter p.Q509* ENST00000446818 NM_001134381.1 509 Caa/Taa 0 +TIAM1 UCSF GRCh37 21 32639259 32639259 + synonymous_variant Silent SNP C C T NOVEL P26_Pri_A Untested WXS Illumina HiSeq 36 16 68 0 ENST00000286827.3:c.30G>A p.Glu10= p.E10= ENST00000286827 NM_003253.2 10 gaG/gaA 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 6 67 73 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +XPO7 UCSF GRCh37 8 21862569 21862569 + synonymous_variant Silent SNP T T C NOVEL P26_Pri_A Untested WXS Illumina HiSeq 240 181 396 1 ENST00000252512.9:c.3234T>C p.Tyr1078= p.Y1078= ENST00000252512 NM_015024.4 1078 taT/taC 0 +AIM2 UCSF GRCh37 1 159032487 159032487 + frameshift_variant Frame_Shift_Del DEL T T - 1000g2010nov_all P26_Pri_B Untested WXS Illumina HiSeq 6 0 ENST00000368130.4:c.1027delA p.Thr343HisfsTer14 p.T343Hfs*14 ENST00000368130 NM_004833.1 343 Aca/ca 0 +ANK3 UCSF GRCh37 10 61946630 61946630 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 27 21 101 0 ENST00000280772.2:c.1928A>G p.Gln643Arg p.Q643R ENST00000280772 NM_020987.3 643 cAg/cGg 0 +ATRX UCSF GRCh37 X 76909677 76909681 + frameshift_variant Frame_Shift_Del DEL CTTTC CTTTC - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 85 0 ENST00000373344.5:c.4224_4228del p.Lys1408AsnfsTer11 p.K1408Nfs*11 ENST00000373344 NM_000489.3 1408 aaGAAAGca/aaca 0 +C20orf96(NM_080571:exon2:c.17+2->TA) UCSF GRCh37 20 271226 271227 + splice_region_variant,intron_variant Splice_Region INS - - TA NOVEL P26_Pri_B Untested WXS Illumina HiSeq 11 0 ENST00000360321.2:c.20+6_20+7dup p.X7_splice ENST00000360321 NM_153269.2 0 +CDC27 UCSF GRCh37 17 45234707 45234707 + missense_variant Missense_Mutation SNP T T A 1000g2010nov_all_0.209,snp132_rs75353677 P26_Pri_B Untested WXS Illumina HiSeq 44 7 47 1 ENST00000531206.1:c.519A>T p.Leu173Phe p.L173F ENST00000531206 173 ttA/ttT 0 +CHD4 UCSF GRCh37 12 6692539 6692539 + synonymous_variant Silent SNP T T C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 22 16 49 0 ENST00000357008.2:c.3885A>G p.Glu1295= p.E1295= ENST00000357008 NM_001273.2 1295 gaA/gaG 0 +EMR3 UCSF GRCh37 19 14748981 14748981 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 71 48 163 0 ENST00000253673.5:c.1420G>A p.Val474Ile p.V474I ENST00000253673 NM_032571.3 474 Gtt/Att 0 +EYS UCSF GRCh37 6 66112482 66112482 + missense_variant Missense_Mutation SNP C C G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 81 48 138 0 ENST00000503581.1:c.1073G>C p.Cys358Ser p.C358S ENST00000503581 NM_001142800.1 358 tGt/tCt 0 +FGFR4 UCSF GRCh37 5 176522719 176522719 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 11 6 36 0 ENST00000292408.4:c.1816C>T p.Arg606Trp p.R606W ENST00000292408 NM_213647.1 606 Cgg/Tgg 0 +GAD1 UCSF GRCh37 2 171700560 171700565 + inframe_deletion In_Frame_Del DEL CATATG CATATG - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 55 0 ENST00000358196.3:c.644_649del p.Thr215_Glu217delinsLys p.T215_E217delinsK ENST00000358196 NM_000817.2 215 aCATATGaa/aaa 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 13 10 27 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGHMBP2 UCSF GRCh37 11 68707014 68707014 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 13 9 25 0 ENST00000255078.3:c.2797G>A p.Gly933Ser p.G933S ENST00000255078 NM_002180.2 933 Ggt/Agt 0 +KIF26B UCSF GRCh37 1 245848890 245848890 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 82 47 164 0 ENST00000407071.2:c.2605G>A p.Gly869Arg p.G869R ENST00000407071 NM_018012.3 869 Ggg/Agg 0 +MED12 UCSF GRCh37 X 70357661 70357661 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 82 71 283 0 ENST00000374080.3:c.5912A>C p.Gln1971Pro p.Q1971P ENST00000374080 1971 cAg/cCg 0 +MURC UCSF GRCh37 9 103348678 103348678 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 159 56 156 0 ENST00000307584.5:c.1040A>G p.Gln347Arg p.Q347R ENST00000307584 NM_001018116.2 347 cAg/cGg 0 +NCOA6 UCSF GRCh37 20 33338237 33338237 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 38 29 94 0 ENST00000374796.2:c.1761T>G p.Ile587Met p.I587M ENST00000374796 587 atT/atG 0 +NEUROD6 UCSF GRCh37 7 31378635 31378635 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 6 0 ENST00000297142.3:c.248delA p.Lys83ArgfsTer35 p.K83Rfs*35 ENST00000297142 NM_022728.3 83 aAg/ag 0 +PCNXL3 UCSF GRCh37 11 65383789 65383789 + missense_variant Missense_Mutation SNP T T G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 27 4 61 1 ENST00000355703.3:c.7T>G p.Ser3Ala p.S3A ENST00000355703 NM_032223.2 3 Tcg/Gcg 0 +PGGT1B UCSF GRCh37 5 114552629 114552629 + missense_variant Missense_Mutation SNP T T A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 16 8 25 0 ENST00000419445.1:c.885A>T p.Arg295Ser p.R295S ENST00000419445 NM_005023.3 295 agA/agT 0 +POPDC2 UCSF GRCh37 3 119378815 119378815 + synonymous_variant Silent SNP T T G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 16 10 38 0 ENST00000264231.3:c.456A>C p.Thr152= p.T152= ENST00000264231 NM_022135.2 152 acA/acC 0 +PRG4 UCSF GRCh37 1 186276052 186276052 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 37 6 71 1 ENST00000445192.2:c.1201A>C p.Thr401Pro p.T401P ENST00000445192 NM_005807.3 401 Acc/Ccc 0 +PRICKLE4 UCSF GRCh37 6 41754576 41754595 + protein_altering_variant In_Frame_Ins INS CGCTGCTGCCGGCGGTTCCA CGCTGCTGCCGGCGGTTCCA TCTCGCTGCTGCCGGCGGTTTCC NOVEL P26_Pri_B Untested WXS Illumina HiSeq 14 0 ENST00000458694.1:c.864_883delinsTCTCGCTGCTGCCGGCGGTTTCC p.Ala289_Ser295delinsLeuAlaAlaAlaGlyGlyPheArg p.A289_S295delinsLAAAGGFR ENST00000458694 NM_013397.5 288 ctCGCTGCTGCCGGCGGTTCCAgc/ctTCTCGCTGCTGCCGGCGGTTTCCgc 0 +RBM45 UCSF GRCh37 2 178988920 178988920 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 6 0 ENST00000286070.5:c.1143delA p.Ala382LeufsTer7 p.A382Lfs*7 ENST00000286070 NM_152945.2 379 Aaa/aa 0 +RELN UCSF GRCh37 7 103138574 103138574 + synonymous_variant Silent SNP T T G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 138 37 153 0 ENST00000428762.1:c.8793A>C p.Gly2931= p.G2931= ENST00000428762 NM_005045.3 2931 ggA/ggC 0 +SCN9A UCSF GRCh37 2 167056179 167056179 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Pri_B Untested WXS Illumina HiSeq 40 26 92 0 ENST00000409672.1:c.4937T>C p.Ile1646Thr p.I1646T ENST00000409672 NM_002977.3 1646 aTc/aCc 0 +SFI1 UCSF GRCh37 22 32014359 32014359 + synonymous_variant Silent SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 28 27 70 0 ENST00000400288.2:c.3684C>T p.Gly1228= p.G1228= ENST00000400288 NM_001007467.2 1228 ggC/ggT 0 +SLC38A8 UCSF GRCh37 16 84050190 84050190 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 35 18 43 1 ENST00000299709.3:c.1096C>T p.Pro366Ser p.P366S ENST00000299709 NM_001080442.1 366 Cct/Tct 0 +SPP1 UCSF GRCh37 4 88903874 88903875 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P26_Pri_B Untested WXS Illumina HiSeq 92 0 ENST00000395080.3:c.771_772del p.Ser258ArgfsTer4 p.S258Rfs*4 ENST00000395080 NM_001040058.1 257 caTTcc/cacc 0 +TBC1D5 UCSF GRCh37 3 17279718 17279718 + stop_gained Nonsense_Mutation SNP G G A NOVEL P26_Pri_B Untested WXS Illumina HiSeq 206 134 261 0 ENST00000446818.2:c.1525C>T p.Gln509Ter p.Q509* ENST00000446818 NM_001134381.1 509 Caa/Taa 0 +TIAM1 UCSF GRCh37 21 32639259 32639259 + synonymous_variant Silent SNP C C T NOVEL P26_Pri_B Untested WXS Illumina HiSeq 38 20 68 0 ENST00000286827.3:c.30G>A p.Glu10= p.E10= ENST00000286827 NM_003253.2 10 gaG/gaA 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 11 44 73 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +XPO7 UCSF GRCh37 8 21862569 21862569 + synonymous_variant Silent SNP T T C NOVEL P26_Pri_B Untested WXS Illumina HiSeq 262 191 396 1 ENST00000252512.9:c.3234T>C p.Tyr1078= p.Y1078= ENST00000252512 NM_015024.4 1078 taT/taC 0 +ANK3 UCSF GRCh37 10 61946630 61946630 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 56 43 101 0 ENST00000280772.2:c.1928A>G p.Gln643Arg p.Q643R ENST00000280772 NM_020987.3 643 cAg/cGg 0 +ATN1 UCSF GRCh37 12 7044946 7044946 + synonymous_variant Silent SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 667 180 581 0 ENST00000356654.4:c.516A>G p.Pro172= p.P172= ENST00000356654 NM_001007026.1 172 ccA/ccG 0 +ATRX UCSF GRCh37 X 76909677 76909681 + frameshift_variant Frame_Shift_Del DEL CTTTC CTTTC - NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 89 0 ENST00000373344.5:c.4224_4228del p.Lys1408AsnfsTer11 p.K1408Nfs*11 ENST00000373344 NM_000489.3 1408 aaGAAAGca/aaca 0 +BNIP3L UCSF GRCh37 8 26265590 26265590 + missense_variant Missense_Mutation SNP G G C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 140 39 157 0 ENST00000380629.2:c.432G>C p.Trp144Cys p.W144C ENST00000380629 NM_004331.2 144 tgG/tgC 0 +CHD4 UCSF GRCh37 12 6692539 6692539 + synonymous_variant Silent SNP T T C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 49 34 49 0 ENST00000357008.2:c.3885A>G p.Glu1295= p.E1295= ENST00000357008 NM_001273.2 1295 gaA/gaG 0 +CSNK1G1 UCSF GRCh37 15 64496629 64496639 + splice_donor_variant,intron_variant Splice_Site DEL AGGATACTTAC AGGATACTTAC GGATACTTAA NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 8 0 ENST00000303052.7:c.999+1_999+11delinsTTAAGTATCC p.X333_splice ENST00000303052 NM_022048.3 0 +EMR3 UCSF GRCh37 19 14748981 14748981 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 125 72 163 0 ENST00000253673.5:c.1420G>A p.Val474Ile p.V474I ENST00000253673 NM_032571.3 474 Gtt/Att 0 +ESX1 UCSF GRCh37 X 103495090 103495090 + missense_variant Missense_Mutation SNP G G C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 16 9 10 1 ENST00000372588.4:c.1040C>G p.Pro347Arg p.P347R ENST00000372588 NM_153448.3 347 cCt/cGt 0 +EYS UCSF GRCh37 6 66112482 66112482 + missense_variant Missense_Mutation SNP C C G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 107 85 138 0 ENST00000503581.1:c.1073G>C p.Cys358Ser p.C358S ENST00000503581 NM_001142800.1 358 tGt/tCt 0 +FAM108A1 UCSF GRCh37 19 1881408 1881408 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 8 6 11 0 ENST00000250974.9:c.158T>C p.Leu53Ser p.L53S ENST00000250974 NM_031213.3 53 tTg/tCg 0 +FGFR4 UCSF GRCh37 5 176522719 176522719 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 20 27 36 0 ENST00000292408.4:c.1816C>T p.Arg606Trp p.R606W ENST00000292408 NM_213647.1 606 Cgg/Tgg 0 +GAD1 UCSF GRCh37 2 171700560 171700565 + inframe_deletion In_Frame_Del DEL CATATG CATATG - NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 68 0 ENST00000358196.3:c.644_649del p.Thr215_Glu217delinsLys p.T215_E217delinsK ENST00000358196 NM_000817.2 215 aCATATGaa/aaa 0 +GPRC6A UCSF GRCh37 6 117114050 117114050 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.00362,snp132_rs118009892 P26_Rec1_A Untested WXS Illumina HiSeq 399 129 373 0 ENST00000310357.3:c.2036C>T p.Thr679Met p.T679M ENST00000310357 NM_148963.2 679 aCg/aTg 0 +HSPA6 UCSF GRCh37 1 161495338 161495338 + missense_variant Missense_Mutation SNP C C A 1000g2010nov_all_0.001,1000g2011may_all_0.0102,snp132_rs41297718 P26_Rec1_A Untested WXS Illumina HiSeq 15 3 9 0 ENST00000309758.4:c.890C>A p.Thr297Lys p.T297K ENST00000309758 NM_002155.3 297 aCg/aAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 16 21 27 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGHMBP2 UCSF GRCh37 11 68707014 68707014 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 23 11 25 0 ENST00000255078.3:c.2797G>A p.Gly933Ser p.G933S ENST00000255078 NM_002180.2 933 Ggt/Agt 0 +KIF26B UCSF GRCh37 1 245848890 245848890 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 115 102 164 0 ENST00000407071.2:c.2605G>A p.Gly869Arg p.G869R ENST00000407071 NM_018012.3 869 Ggg/Agg 0 +KIR2DS4 UCSF GRCh37 19 55349113 55349113 + synonymous_variant Silent SNP G G A snp132_rs1049284 P26_Rec1_A Untested WXS Illumina HiSeq 18 4 18 1 ENST00000339924.8:c.153G>A p.Ser51= p.S51= ENST00000339924 NM_001281971.1 51 tcG/tcA 0 +KRT8 UCSF GRCh37 12 53298675 53298675 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 13 3 25 0 ENST00000552150.1:c.175T>G p.Ser59Ala p.S59A ENST00000552150 NM_001256282.1 59 Tcc/Gcc 0 +MED12 UCSF GRCh37 X 70357661 70357661 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 255 131 283 0 ENST00000374080.3:c.5912A>C p.Gln1971Pro p.Q1971P ENST00000374080 1971 cAg/cCg 0 +MURC UCSF GRCh37 9 103348678 103348678 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 197 43 156 0 ENST00000307584.5:c.1040A>G p.Gln347Arg p.Q347R ENST00000307584 NM_001018116.2 347 cAg/cGg 0 +MYBPC2 UCSF GRCh37 19 50967755 50967755 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 137 36 103 0 ENST00000357701.5:c.3381C>T p.Gly1127= p.G1127= ENST00000357701 NM_004533.3 1127 ggC/ggT 0 +MYO1G UCSF GRCh37 7 45009376 45009376 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 507 60 459 0 ENST00000258787.7:c.1431C>T p.Thr477= p.T477= ENST00000258787 NM_033054.2 477 acC/acT 0 +NBPF10 UCSF GRCh37 1 145293510 145293510 + missense_variant Missense_Mutation SNP C C G 1000g2010nov_all_0.173,snp132_rs4356110 P26_Rec1_A Untested WXS Illumina HiSeq 22 5 14 1 ENST00000342960.5:c.105C>G p.Phe35Leu p.F35L ENST00000342960 NM_001039703.5 35 ttC/ttG 0 +NBPF10 UCSF GRCh37 1 145293498 145293498 + missense_variant Missense_Mutation SNP G G C 1000g2010nov_all_0.245,1000g2011may_all_0.29821,snp132_rs4409714 P26_Rec1_A Untested WXS Illumina HiSeq 23 4 13 0 ENST00000342960.5:c.93G>C p.Lys31Asn p.K31N ENST00000342960 NM_001039703.5 31 aaG/aaC 0 +NBPF10 UCSF GRCh37 1 145293490 145293490 + missense_variant Missense_Mutation SNP G G C 1000g2010nov_all_0.242,1000g2011may_all_0.26292,snp132_rs6671335 P26_Rec1_A Untested WXS Illumina HiSeq 23 5 13 0 ENST00000342960.5:c.85G>C p.Ala29Pro p.A29P ENST00000342960 NM_001039703.5 29 Gca/Cca 0 +NCOA6 UCSF GRCh37 20 33338237 33338237 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 80 54 94 0 ENST00000374796.2:c.1761T>G p.Ile587Met p.I587M ENST00000374796 587 atT/atG 0 +PGGT1B UCSF GRCh37 5 114552629 114552629 + missense_variant Missense_Mutation SNP T T A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 22 12 25 0 ENST00000419445.1:c.885A>T p.Arg295Ser p.R295S ENST00000419445 NM_005023.3 295 agA/agT 0 +POTED UCSF GRCh37 21 14982676 14982676 + missense_variant Missense_Mutation SNP A A G snp132_rs2605913 P26_Rec1_A Untested WXS Illumina HiSeq 19 3 23 1 ENST00000299443.5:c.127A>G p.Met43Val p.M43V ENST00000299443 NM_174981.3 43 Atg/Gtg 0 +RBM45 UCSF GRCh37 2 178988920 178988920 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 7 0 ENST00000286070.5:c.1143delA p.Ala382LeufsTer7 p.A382Lfs*7 ENST00000286070 NM_152945.2 379 Aaa/aa 0 +RBMX UCSF GRCh37 X 135958696 135958696 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.08188,snp132_rs112800567 P26_Rec1_A Untested WXS Illumina HiSeq 20 6 20 1 ENST00000320676.7:c.507A>G p.Gly169= p.G169= ENST00000320676 NM_002139.3 169 ggA/ggG 0 +SCN9A UCSF GRCh37 2 167056179 167056179 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 56 42 92 0 ENST00000409672.1:c.4937T>C p.Ile1646Thr p.I1646T ENST00000409672 NM_002977.3 1646 aTc/aCc 0 +SELE UCSF GRCh37 1 169698648 169698648 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 219 49 201 0 ENST00000333360.7:c.882C>T p.Asn294= p.N294= ENST00000333360 NM_000450.2 294 aaC/aaT 0 +SFI1 UCSF GRCh37 22 32014359 32014359 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 52 57 70 0 ENST00000400288.2:c.3684C>T p.Gly1228= p.G1228= ENST00000400288 NM_001007467.2 1228 ggC/ggT 0 +SLC38A8 UCSF GRCh37 16 84050190 84050190 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 39 26 43 1 ENST00000299709.3:c.1096C>T p.Pro366Ser p.P366S ENST00000299709 NM_001080442.1 366 Cct/Tct 0 +SPP1 UCSF GRCh37 4 88903874 88903875 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 136 0 ENST00000395080.3:c.771_772del p.Ser258ArgfsTer4 p.S258Rfs*4 ENST00000395080 NM_001040058.1 257 caTTcc/cacc 0 +TBC1D5 UCSF GRCh37 3 17279718 17279718 + stop_gained Nonsense_Mutation SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 220 152 261 0 ENST00000446818.2:c.1525C>T p.Gln509Ter p.Q509* ENST00000446818 NM_001134381.1 509 Caa/Taa 0 +TIAM1 UCSF GRCh37 21 32639259 32639259 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 50 45 68 0 ENST00000286827.3:c.30G>A p.Glu10= p.E10= ENST00000286827 NM_003253.2 10 gaG/gaA 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 16 76 73 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +TXLNB UCSF GRCh37 6 139563882 139563882 + synonymous_variant Silent SNP A A G NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 153 33 98 0 ENST00000358430.3:c.1836T>C p.Gly612= p.G612= ENST00000358430 NM_153235.3 612 ggT/ggC 0 +WNK3 UCSF GRCh37 X 54224946 54224946 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 148 42 121 0 ENST00000354646.2:c.5214C>T p.His1738= p.H1738= ENST00000354646 NM_020922.4 1738 caC/caT 0 +XPO7 UCSF GRCh37 8 21862569 21862569 + synonymous_variant Silent SNP T T C NOVEL P26_Rec1_A Untested WXS Illumina HiSeq 309 236 396 1 ENST00000252512.9:c.3234T>C p.Tyr1078= p.Y1078= ENST00000252512 NM_015024.4 1078 taT/taC 0 +ANK3 UCSF GRCh37 10 61946630 61946630 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 26 15 101 0 ENST00000280772.2:c.1928A>G p.Gln643Arg p.Q643R ENST00000280772 NM_020987.3 643 cAg/cGg 0 +ATN1 UCSF GRCh37 12 7044946 7044946 + synonymous_variant Silent SNP A A G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 268 64 581 0 ENST00000356654.4:c.516A>G p.Pro172= p.P172= ENST00000356654 NM_001007026.1 172 ccA/ccG 0 +ATRX UCSF GRCh37 X 76909677 76909681 + frameshift_variant Frame_Shift_Del DEL CTTTC CTTTC - NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 73 0 ENST00000373344.5:c.4224_4228del p.Lys1408AsnfsTer11 p.K1408Nfs*11 ENST00000373344 NM_000489.3 1408 aaGAAAGca/aaca 0 +BNIP3L UCSF GRCh37 8 26265590 26265590 + missense_variant Missense_Mutation SNP G G C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 110 24 157 0 ENST00000380629.2:c.432G>C p.Trp144Cys p.W144C ENST00000380629 NM_004331.2 144 tgG/tgC 0 +C8A UCSF GRCh37 1 57351611 57351611 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.008,1000g2011may_all_0.0213,snp132_rs77289345 P26_Rec1_B Untested WXS Illumina HiSeq 39 6 66 0 ENST00000361249.3:c.867C>T p.Phe289= p.F289= ENST00000361249 NM_000562.2 289 ttC/ttT 0 +CHD4 UCSF GRCh37 12 6692539 6692539 + synonymous_variant Silent SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 14 11 49 0 ENST00000357008.2:c.3885A>G p.Glu1295= p.E1295= ENST00000357008 NM_001273.2 1295 gaA/gaG 0 +DYNC1H1 UCSF GRCh37 14 102468978 102468978 + synonymous_variant Silent SNP T T G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 18 6 49 0 ENST00000360184.4:c.4647T>G p.Gly1549= p.G1549= ENST00000360184 NM_001376.4 1549 ggT/ggG 0 +EFS UCSF GRCh37 14 23828664 23828664 + synonymous_variant Silent SNP T T G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 26 8 72 1 ENST00000216733.3:c.1023A>C p.Pro341= p.P341= ENST00000216733 NM_005864.3 341 ccA/ccC 0 +EMR3 UCSF GRCh37 19 14748981 14748981 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 51 38 163 0 ENST00000253673.5:c.1420G>A p.Val474Ile p.V474I ENST00000253673 NM_032571.3 474 Gtt/Att 0 +EYS UCSF GRCh37 6 66112482 66112482 + missense_variant Missense_Mutation SNP C C G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 58 57 138 0 ENST00000503581.1:c.1073G>C p.Cys358Ser p.C358S ENST00000503581 NM_001142800.1 358 tGt/tCt 0 +FGFR4 UCSF GRCh37 5 176522719 176522719 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 3 16 36 0 ENST00000292408.4:c.1816C>T p.Arg606Trp p.R606W ENST00000292408 NM_213647.1 606 Cgg/Tgg 0 +GAD1 UCSF GRCh37 2 171700560 171700565 + inframe_deletion In_Frame_Del DEL CATATG CATATG - NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 44 0 ENST00000358196.3:c.644_649del p.Thr215_Glu217delinsLys p.T215_E217delinsK ENST00000358196 NM_000817.2 215 aCATATGaa/aaa 0 +GPRC6A UCSF GRCh37 6 117114050 117114050 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.003,1000g2011may_all_0.00362,snp132_rs118009892 P26_Rec1_B Untested WXS Illumina HiSeq 236 59 373 0 ENST00000310357.3:c.2036C>T p.Thr679Met p.T679M ENST00000310357 NM_148963.2 679 aCg/aTg 0 +HERC3 UCSF GRCh37 4 89627987 89627987 + missense_variant Missense_Mutation SNP A A T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 170 27 388 0 ENST00000402738.1:c.3029A>T p.Glu1010Val p.E1010V ENST00000402738 NM_014606.2 1010 gAg/gTg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 10 9 27 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IGHMBP2 UCSF GRCh37 11 68707014 68707014 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 9 12 25 0 ENST00000255078.3:c.2797G>A p.Gly933Ser p.G933S ENST00000255078 NM_002180.2 933 Ggt/Agt 0 +IL17RA UCSF GRCh37 22 17581248 17581248 + missense_variant Missense_Mutation SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 148 19 309 0 ENST00000319363.6:c.427C>T p.Arg143Cys p.R143C ENST00000319363 NM_014339.6 143 Cgt/Tgt 0 +KIF26B UCSF GRCh37 1 245848890 245848890 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 36 36 164 0 ENST00000407071.2:c.2605G>A p.Gly869Arg p.G869R ENST00000407071 NM_018012.3 869 Ggg/Agg 0 +MED12 UCSF GRCh37 X 70357661 70357661 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 64 43 283 0 ENST00000374080.3:c.5912A>C p.Gln1971Pro p.Q1971P ENST00000374080 1971 cAg/cCg 0 +MURC UCSF GRCh37 9 103348678 103348678 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 146 24 156 0 ENST00000307584.5:c.1040A>G p.Gln347Arg p.Q347R ENST00000307584 NM_001018116.2 347 cAg/cGg 0 +MYBPC2 UCSF GRCh37 19 50967755 50967755 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 60 12 103 0 ENST00000357701.5:c.3381C>T p.Gly1127= p.G1127= ENST00000357701 NM_004533.3 1127 ggC/ggT 0 +NCOA6 UCSF GRCh37 20 33338237 33338237 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 39 22 94 0 ENST00000374796.2:c.1761T>G p.Ile587Met p.I587M ENST00000374796 587 atT/atG 0 +PRICKLE4 UCSF GRCh37 6 41754576 41754595 + protein_altering_variant In_Frame_Ins INS CGCTGCTGCCGGCGGTTCCA CGCTGCTGCCGGCGGTTCCA TCTCGCTGCTGCCGGCGGTTTCC NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 6 0 ENST00000458694.1:c.864_883delinsTCTCGCTGCTGCCGGCGGTTTCC p.Ala289_Ser295delinsLeuAlaAlaAlaGlyGlyPheArg p.A289_S295delinsLAAAGGFR ENST00000458694 NM_013397.5 288 ctCGCTGCTGCCGGCGGTTCCAgc/ctTCTCGCTGCTGCCGGCGGTTTCCgc 0 +RBMX UCSF GRCh37 X 135958696 135958696 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.08188,snp132_rs112800567 P26_Rec1_B Untested WXS Illumina HiSeq 13 3 20 1 ENST00000320676.7:c.507A>G p.Gly169= p.G169= ENST00000320676 NM_002139.3 169 ggA/ggG 0 +SCN9A UCSF GRCh37 2 167056179 167056179 + missense_variant Missense_Mutation SNP A A G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 35 26 92 0 ENST00000409672.1:c.4937T>C p.Ile1646Thr p.I1646T ENST00000409672 NM_002977.3 1646 aTc/aCc 0 +SELE UCSF GRCh37 1 169698648 169698648 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 86 32 201 0 ENST00000333360.7:c.882C>T p.Asn294= p.N294= ENST00000333360 NM_000450.2 294 aaC/aaT 0 +SFI1 UCSF GRCh37 22 32014359 32014359 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 15 18 70 0 ENST00000400288.2:c.3684C>T p.Gly1228= p.G1228= ENST00000400288 NM_001007467.2 1228 ggC/ggT 0 +SLC38A8 UCSF GRCh37 16 84050190 84050190 + missense_variant Missense_Mutation SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 12 12 43 1 ENST00000299709.3:c.1096C>T p.Pro366Ser p.P366S ENST00000299709 NM_001080442.1 366 Cct/Tct 0 +SPP1 UCSF GRCh37 4 88903874 88903875 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 60 0 ENST00000395080.3:c.771_772del p.Ser258ArgfsTer4 p.S258Rfs*4 ENST00000395080 NM_001040058.1 257 caTTcc/cacc 0 +TBC1D5 UCSF GRCh37 3 17279718 17279718 + stop_gained Nonsense_Mutation SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 158 127 261 0 ENST00000446818.2:c.1525C>T p.Gln509Ter p.Q509* ENST00000446818 NM_001134381.1 509 Caa/Taa 0 +TIAM1 UCSF GRCh37 21 32639259 32639259 + synonymous_variant Silent SNP C C T NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 22 28 68 0 ENST00000286827.3:c.30G>A p.Glu10= p.E10= ENST00000286827 NM_003253.2 10 gaG/gaA 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 2 32 73 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +TRIM3 UCSF GRCh37 11 6472156 6472156 + missense_variant Missense_Mutation SNP A A C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 29 7 74 0 ENST00000525074.1:c.1836T>G p.Phe612Leu p.F612L ENST00000525074 NM_001248006.1 612 ttT/ttG 0 +TXLNB UCSF GRCh37 6 139563882 139563882 + synonymous_variant Silent SNP A A G NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 58 10 98 0 ENST00000358430.3:c.1836T>C p.Gly612= p.G612= ENST00000358430 NM_153235.3 612 ggT/ggC 0 +USP51 UCSF GRCh37 X 55514172 55514172 + missense_variant Missense_Mutation SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 135 18 193 0 ENST00000500968.3:c.1201A>G p.Thr401Ala p.T401A ENST00000500968 NM_201286.3 401 Aca/Gca 0 +WNK3 UCSF GRCh37 X 54224946 54224946 + synonymous_variant Silent SNP G G A NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 75 14 121 0 ENST00000354646.2:c.5214C>T p.His1738= p.H1738= ENST00000354646 NM_020922.4 1738 caC/caT 0 +XPO7 UCSF GRCh37 8 21862569 21862569 + synonymous_variant Silent SNP T T C NOVEL P26_Rec1_B Untested WXS Illumina HiSeq 186 184 396 1 ENST00000252512.9:c.3234T>C p.Tyr1078= p.Y1078= ENST00000252512 NM_015024.4 1078 taT/taC 0 +AKR1D1 UCSF GRCh37 7 137791441 137791441 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 182 63 221 0 ENST00000242375.3:c.667G>C p.Gly223Arg p.G223R ENST00000242375 NM_005989.3 223 Ggg/Cgg 0 +AMIGO1 UCSF GRCh37 1 110051079 110051079 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 149 67 207 0 ENST00000369864.4:c.456C>T p.Cys152= p.C152= ENST00000369864 152 tgC/tgT 0 +ATRX UCSF GRCh37 X 76938099 76938100 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P27_Pri_A Untested WXS Illumina HiSeq 121 0 ENST00000373344.5:c.2648_2649del p.Gln883ArgfsTer13 p.Q883Rfs*13 ENST00000373344 NM_000489.3 883 cAA/c 0 +BIRC6 UCSF GRCh37 2 32740799 32740823 + frameshift_variant Frame_Shift_Del DEL ATTTCATGCCATCCTAATAATCAAA ATTTCATGCCATCCTAATAATCAAA - NOVEL P27_Pri_A Untested WXS Illumina HiSeq 6 0 ENST00000421745.2:c.11312_11336del p.Ile3771SerfsTer2 p.I3771Sfs*2 ENST00000421745 NM_016252.3 3771 ATTTCATGCCATCCTAATAATCAAAag/ag 0 +CDKN2A UCSF GRCh37 9 21970993 21970993 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P27_Pri_A Untested WXS Illumina HiSeq 9 0 ENST00000304494.5:c.365del p.Gly122AlafsTer24 p.G122Afs*24 ENST00000304494 NM_000077.4 122 gGc/gc 0 +CNTNAP2 UCSF GRCh37 7 147844772 147844772 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 71 18 57 0 ENST00000361727.3:c.2744G>A p.Arg915His p.R915H ENST00000361727 NM_014141.5 915 cGc/cAc 0 +CTNND2 UCSF GRCh37 5 11364832 11364832 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 29 25 49 0 ENST00000304623.8:c.1348A>G p.Thr450Ala p.T450A ENST00000304623 NM_001332.2 450 Acc/Gcc 0 +DMWD UCSF GRCh37 19 46287928 46287928 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 68 66 142 0 ENST00000270223.6:c.1948C>T p.Pro650Ser p.P650S ENST00000270223 NM_004943.1 650 Ccc/Tcc 0 +DNAJC11 UCSF GRCh37 1 6700009 6700009 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 45 18 63 0 ENST00000377577.5:c.1206C>T p.Ala402= p.A402= ENST00000377577 NM_018198.3 402 gcC/gcT 0 +DUOXA2 UCSF GRCh37 15 45408389 45408389 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 155 113 307 0 ENST00000323030.5:c.273C>T p.Ser91= p.S91= ENST00000323030 NM_207581.3 91 agC/agT 0 +FLG UCSF GRCh37 1 152284325 152284325 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 28 18 47 0 ENST00000368799.1:c.3037T>C p.Ser1013Pro p.S1013P ENST00000368799 NM_002016.1 1013 Tcc/Ccc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 7 25 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL11 UCSF GRCh37 19 55879672 55879672 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.010,1000g2011may_all_0.0145,snp132_rs4252548 P27_Pri_A Untested WXS Illumina HiSeq 17 11 31 0 ENST00000264563.2:c.335G>A p.Arg112His p.R112H ENST00000264563 NM_000641.3 112 cGc/cAc 0 +KATNB1 UCSF GRCh37 16 57787370 57787370 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 99 49 116 0 ENST00000379661.3:c.1116C>T p.Ser372= p.S372= ENST00000379661 NM_005886.2 372 tcC/tcT 0 +KRT12 UCSF GRCh37 17 39023245 39023246 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 151 0 ENST00000251643.4:c.194dup p.Ser66Ter p.S66* ENST00000251643 NM_000223.3 65 tct/tCct 0 +KRTAP4-6 UCSF GRCh37 17 39296422 39296422 + synonymous_variant Silent SNP A A G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 24 6 19 0 ENST00000345847.4:c.318T>C p.Arg106= p.R106= ENST00000345847 NM_030976.1 106 cgT/cgC 0 +MUC6 UCSF GRCh37 11 1031684 1031684 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 106 41 158 0 ENST00000421673.2:c.406G>A p.Gly136Ser p.G136S ENST00000421673 NM_005961.2 136 Ggc/Agc 0 +MYO18B UCSF GRCh37 22 26159269 26159269 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 105 80 213 0 ENST00000335473.7:c.111C>T p.Phe37= p.F37= ENST00000335473 NM_032608.5 37 ttC/ttT 0 +NBPF1 UCSF GRCh37 1 16918473 16918473 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.016,snp132_rs60465633 P27_Pri_A somatic WXS Sanger Illumina HiSeq 19 4 23 1 ENST00000430580.2:c.44C>T p.Thr15Met p.T15M ENST00000430580 NM_017940.4 15 aCg/aTg 0 +OGFR UCSF GRCh37 20 61444845 61444845 + synonymous_variant Silent SNP G G A snp132_rs112106909 P27_Pri_A Untested WXS Illumina HiSeq 16 3 18 1 ENST00000290291.6:c.1878G>A p.Pro626= p.P626= ENST00000290291 NM_007346.2 626 ccG/ccA 0 +OR10AG1 UCSF GRCh37 11 55735772 55735772 + missense_variant Missense_Mutation SNP A A T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 109 43 166 1 ENST00000312345.2:c.168T>A p.Asn56Lys p.N56K ENST00000312345 NM_001005491.1 56 aaT/aaA 0 +POTEH UCSF GRCh37 22 16287368 16287368 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 13 5 14 0 ENST00000343518.6:c.518G>A p.Arg173His p.R173H ENST00000343518 NM_001136213.1 173 cGt/cAt 0 +PRAMEF20 UCSF GRCh37 1 13743058 13743058 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.039,1000g2011may_all_0.0457,snp132_rs77164784 P27_Pri_A Untested WXS Illumina HiSeq 14 8 17 0 ENST00000316412.5:c.247G>A p.Asp83Asn p.D83N ENST00000316412 NM_001099852.1 83 Gat/Aat 0 +PRF1 UCSF GRCh37 10 72358862 72358862 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 41 41 107 0 ENST00000441259.1:c.615C>T p.Asn205= p.N205= ENST00000441259 NM_005041.4 205 aaC/aaT 0 +PRSS50 UCSF GRCh37 3 46753929 46753929 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 32 22 43 0 ENST00000460241.1:c.965G>T p.Trp322Leu p.W322L ENST00000460241 322 tGg/tTg 0 +PSKH2 UCSF GRCh37 8 87060758 87060758 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 66 45 160 0 ENST00000276616.2:c.1091A>G p.Lys364Arg p.K364R ENST00000276616 NM_033126.1 364 aAa/aGa 0 +SCN2A UCSF GRCh37 2 166237141 166237141 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 173 26 138 0 ENST00000357398.3:c.4348T>G p.Tyr1450Asp p.Y1450D ENST00000357398 1450 Tat/Gat 0 +SEMA4D UCSF GRCh37 9 92008491 92008491 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 29 20 76 0 ENST00000450295.1:c.494C>T p.Thr165Ile p.T165I ENST00000450295 165 aCa/aTa 0 +SLCO6A1 UCSF GRCh37 5 101735273 101735273 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 61 32 63 0 ENST00000506729.1:c.1800C>T p.Val600= p.V600= ENST00000506729 600 gtC/gtT 0 +SMARCA4 UCSF GRCh37 19 11141559 11141559 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Pri_A somatic WXS Sanger Illumina HiSeq 22 4 36 0 ENST00000344626.4:c.3536A>G p.Asn1179Ser p.N1179S ENST00000344626 NM_003072.3 1179 aAt/aGt 0 +SPHKAP UCSF GRCh37 2 228883637 228883637 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 114 104 199 0 ENST00000392056.3:c.1933A>G p.Arg645Gly p.R645G ENST00000392056 NM_001142644.1 645 Agg/Ggg 0 +TMEM95 UCSF GRCh37 17 7258580 7258580 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_A Untested WXS Illumina HiSeq 69 42 118 0 ENST00000330767.4:c.57C>T p.Phe19= p.F19= ENST00000330767 NM_198154.1 19 ttC/ttT 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 14 71 71 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +WDR62 UCSF GRCh37 19 36585008 36585008 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_A Untested WXS Illumina HiSeq 114 45 166 0 ENST00000401500.2:c.2409G>A p.Glu803= p.E803= ENST00000401500 NM_001083961.1 803 gaG/gaA 0 +ZKSCAN4 UCSF GRCh37 6 28213206 28213206 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Pri_A Untested WXS Illumina HiSeq 280 197 579 0 ENST00000377294.2:c.1326G>C p.Arg442Ser p.R442S ENST00000377294 NM_019110.3 442 agG/agC 0 +ZSWIM5 UCSF GRCh37 1 45516885 45516885 + synonymous_variant Silent SNP T T C NOVEL P27_Pri_A Untested WXS Illumina HiSeq 59 66 186 0 ENST00000359600.5:c.1293A>G p.Lys431= p.K431= ENST00000359600 NM_020883.1 431 aaA/aaG 0 +ABI3BP UCSF GRCh37 3 100712213 100712213 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 44 5 75 0 ENST00000284322.5:c.37G>T p.Gly13Trp p.G13W ENST00000284322 NM_015429.3 13 Ggg/Tgg 0 +AKR1D1 UCSF GRCh37 7 137791441 137791441 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 137 63 221 0 ENST00000242375.3:c.667G>C p.Gly223Arg p.G223R ENST00000242375 NM_005989.3 223 Ggg/Cgg 0 +AMIGO1 UCSF GRCh37 1 110051079 110051079 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 76 38 207 0 ENST00000369864.4:c.456C>T p.Cys152= p.C152= ENST00000369864 152 tgC/tgT 0 +ANKRD22 UCSF GRCh37 10 90591731 90591731 + missense_variant Missense_Mutation SNP A A C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 36 14 130 0 ENST00000371930.4:c.74T>G p.Val25Gly p.V25G ENST00000371930 NM_144590.2 25 gTg/gGg 0 +ATP7B UCSF GRCh37 13 52524503 52524503 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 36 4 121 0 ENST00000242839.4:c.2480G>T p.Arg827Leu p.R827L ENST00000242839 NM_000053.3 827 cGg/cTg 0 +ATRX UCSF GRCh37 X 76938099 76938100 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P27_Pri_B Untested WXS Illumina HiSeq 96 0 ENST00000373344.5:c.2648_2649del p.Gln883ArgfsTer13 p.Q883Rfs*13 ENST00000373344 NM_000489.3 883 cAA/c 0 +B3GNT3 UCSF GRCh37 19 17918779 17918779 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 24 4 69 0 ENST00000318683.6:c.163C>A p.Arg55Ser p.R55S ENST00000318683 NM_014256.3 55 Cgc/Agc 0 +CBX4 UCSF GRCh37 17 77808322 77808322 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 24 3 58 0 ENST00000269397.4:c.1119G>T p.Pro373= p.P373= ENST00000269397 NM_003655.2 373 ccG/ccT 0 +CCDC60 UCSF GRCh37 12 119773023 119773023 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 34 4 105 0 ENST00000327554.2:c.42C>A p.Pro14= p.P14= ENST00000327554 NM_178499.3 14 ccC/ccA 0 +CNTNAP2 UCSF GRCh37 7 147844772 147844772 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 34 16 57 0 ENST00000361727.3:c.2744G>A p.Arg915His p.R915H ENST00000361727 NM_014141.5 915 cGc/cAc 0 +CTNND2 UCSF GRCh37 5 11364832 11364832 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 16 10 49 0 ENST00000304623.8:c.1348A>G p.Thr450Ala p.T450A ENST00000304623 NM_001332.2 450 Acc/Gcc 0 +DMWD UCSF GRCh37 19 46287928 46287928 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 37 42 142 0 ENST00000270223.6:c.1948C>T p.Pro650Ser p.P650S ENST00000270223 NM_004943.1 650 Ccc/Tcc 0 +DNAJC11 UCSF GRCh37 1 6700009 6700009 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 20 13 63 0 ENST00000377577.5:c.1206C>T p.Ala402= p.A402= ENST00000377577 NM_018198.3 402 gcC/gcT 0 +DUOXA2 UCSF GRCh37 15 45408389 45408389 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 67 42 307 0 ENST00000323030.5:c.273C>T p.Ser91= p.S91= ENST00000323030 NM_207581.3 91 agC/agT 0 +FLG UCSF GRCh37 1 152284325 152284325 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 15 10 47 0 ENST00000368799.1:c.3037T>C p.Ser1013Pro p.S1013P ENST00000368799 NM_002016.1 1013 Tcc/Ccc 0 +FMN2 UCSF GRCh37 1 240255560 240255560 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 35 19 85 0 ENST00000319653.9:c.151G>A p.Gly51Arg p.G51R ENST00000319653 NM_020066.4 51 Ggg/Agg 0 +FUCA1 UCSF GRCh37 1 24181025 24181025 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 36 4 51 0 ENST00000374479.3:c.794G>T p.Trp265Leu p.W265L ENST00000374479 NM_000147.4 265 tGg/tTg 0 +GGA2 UCSF GRCh37 16 23481419 23481419 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 27 3 57 0 ENST00000309859.4:c.1518G>T p.Thr506= p.T506= ENST00000309859 NM_015044.4 506 acG/acT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 10 16 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +INPP5F UCSF GRCh37 10 121556378 121556378 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 13 3 37 0 ENST00000361976.2:c.821C>A p.Pro274Gln p.P274Q ENST00000361976 NM_014937.3 274 cCa/cAa 0 +KATNB1 UCSF GRCh37 16 57787370 57787370 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 24 27 116 0 ENST00000379661.3:c.1116C>T p.Ser372= p.S372= ENST00000379661 NM_005886.2 372 tcC/tcT 0 +KRT12 UCSF GRCh37 17 39023245 39023246 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 63 0 ENST00000251643.4:c.194dup p.Ser66Ter p.S66* ENST00000251643 NM_000223.3 65 tct/tCct 0 +MATK UCSF GRCh37 19 3784435 3784435 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 19 3 28 0 ENST00000395045.2:c.150G>T p.Pro50= p.P50= ENST00000395045 NM_002378.3 50 ccG/ccT 0 +MUC6 UCSF GRCh37 11 1031684 1031684 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 46 18 158 0 ENST00000421673.2:c.406G>A p.Gly136Ser p.G136S ENST00000421673 NM_005961.2 136 Ggc/Agc 0 +MYO18B UCSF GRCh37 22 26159269 26159269 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 36 24 213 0 ENST00000335473.7:c.111C>T p.Phe37= p.F37= ENST00000335473 NM_032608.5 37 ttC/ttT 0 +NBPF1 UCSF GRCh37 1 16893813 16893813 + synonymous_variant Silent SNP A A G snp132_rs58611269 P27_Pri_B Untested WXS Illumina HiSeq 11 4 19 0 ENST00000430580.2:c.2700T>C p.Pro900= p.P900= ENST00000430580 NM_017940.4 900 ccT/ccC 0 +OPN4 UCSF GRCh37 10 88418431 88418431 + synonymous_variant Silent SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 18 3 31 0 ENST00000372071.2:c.648C>A p.Pro216= p.P216= ENST00000372071 NM_001030015.2 216 ccC/ccA 0 +OR10AG1 UCSF GRCh37 11 55735772 55735772 + missense_variant Missense_Mutation SNP A A T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 55 23 166 1 ENST00000312345.2:c.168T>A p.Asn56Lys p.N56K ENST00000312345 NM_001005491.1 56 aaT/aaA 0 +PRF1 UCSF GRCh37 10 72358862 72358862 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 18 15 107 0 ENST00000441259.1:c.615C>T p.Asn205= p.N205= ENST00000441259 NM_005041.4 205 aaC/aaT 0 +PRSS50 UCSF GRCh37 3 46753929 46753929 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 19 11 43 0 ENST00000460241.1:c.965G>T p.Trp322Leu p.W322L ENST00000460241 322 tGg/tTg 0 +PSKH2 UCSF GRCh37 8 87060758 87060758 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 38 28 160 0 ENST00000276616.2:c.1091A>G p.Lys364Arg p.K364R ENST00000276616 NM_033126.1 364 aAa/aGa 0 +RASGRP2 UCSF GRCh37 11 64509576 64509576 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 24 3 73 0 ENST00000354024.3:c.82G>T p.Gly28Trp p.G28W ENST00000354024 NM_153819.1 28 Ggg/Tgg 0 +SCN2A UCSF GRCh37 2 166237141 166237141 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 106 13 138 0 ENST00000357398.3:c.4348T>G p.Tyr1450Asp p.Y1450D ENST00000357398 1450 Tat/Gat 0 +SEMA4D UCSF GRCh37 9 92008491 92008491 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 28 17 76 0 ENST00000450295.1:c.494C>T p.Thr165Ile p.T165I ENST00000450295 165 aCa/aTa 0 +SH3BGRL2 UCSF GRCh37 6 80383448 80383448 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 29 4 54 0 ENST00000369838.4:c.163C>A p.Pro55Thr p.P55T ENST00000369838 NM_031469.2 55 Ccg/Acg 0 +SLCO6A1 UCSF GRCh37 5 101735273 101735273 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 37 16 63 0 ENST00000506729.1:c.1800C>T p.Val600= p.V600= ENST00000506729 600 gtC/gtT 0 +SMARCA4 UCSF GRCh37 19 11141559 11141559 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 13 5 36 0 ENST00000344626.4:c.3536A>G p.Asn1179Ser p.N1179S ENST00000344626 NM_003072.3 1179 aAt/aGt 0 +SPHKAP UCSF GRCh37 2 228883637 228883637 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 82 51 199 0 ENST00000392056.3:c.1933A>G p.Arg645Gly p.R645G ENST00000392056 NM_001142644.1 645 Agg/Ggg 0 +TMEM95 UCSF GRCh37 17 7258580 7258580 + synonymous_variant Silent SNP C C T NOVEL P27_Pri_B Untested WXS Illumina HiSeq 26 17 118 0 ENST00000330767.4:c.57C>T p.Phe19= p.F19= ENST00000330767 NM_198154.1 19 ttC/ttT 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 7 25 71 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +WDR62 UCSF GRCh37 19 36585008 36585008 + synonymous_variant Silent SNP G G A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 90 40 166 0 ENST00000401500.2:c.2409G>A p.Glu803= p.E803= ENST00000401500 NM_001083961.1 803 gaG/gaA 0 +ZAK UCSF GRCh37 2 174081976 174081976 + missense_variant,splice_region_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 14 3 29 0 ENST00000375213.3:c.985C>A p.Pro329Thr p.P329T ENST00000375213 NM_016653.2 329 Ccg/Acg 0 +ZKSCAN4 UCSF GRCh37 6 28213206 28213206 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Pri_B Untested WXS Illumina HiSeq 146 103 579 0 ENST00000377294.2:c.1326G>C p.Arg442Ser p.R442S ENST00000377294 NM_019110.3 442 agG/agC 0 +ZNF365 UCSF GRCh37 10 64416220 64416220 + synonymous_variant Silent SNP C C T 1000g2010nov_all_0.011,1000g2011may_all_0.0406,snp132_rs76895268 P27_Pri_B Untested WXS Illumina HiSeq 49 6 71 0 ENST00000410046.3:c.1194C>T p.Asp398= p.D398= ENST00000410046 NM_199451.2 398 gaC/gaT 0 +ZNF674 UCSF GRCh37 X 46360197 46360197 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 28 4 47 0 ENST00000523374.1:c.827G>T p.Gly276Val p.G276V ENST00000523374 NM_001039891.2 276 gGg/gTg 0 +ZSWIM5 UCSF GRCh37 1 45516885 45516885 + synonymous_variant Silent SNP T T C NOVEL P27_Pri_B Untested WXS Illumina HiSeq 35 33 186 0 ENST00000359600.5:c.1293A>G p.Lys431= p.K431= ENST00000359600 NM_020883.1 431 aaA/aaG 0 +ZYX UCSF GRCh37 7 143079428 143079428 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Pri_B Untested WXS Illumina HiSeq 34 4 89 0 ENST00000322764.5:c.296C>A p.Pro99Gln p.P99Q ENST00000322764 NM_003461.4 99 cCg/cAg 0 +AKR1D1 UCSF GRCh37 7 137791441 137791441 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 166 85 221 0 ENST00000242375.3:c.667G>C p.Gly223Arg p.G223R ENST00000242375 NM_005989.3 223 Ggg/Cgg 0 +AMIGO1 UCSF GRCh37 1 110051079 110051079 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 105 86 207 0 ENST00000369864.4:c.456C>T p.Cys152= p.C152= ENST00000369864 152 tgC/tgT 0 +ATP13A2 UCSF GRCh37 1 17316753 17316753 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 58 9 77 0 ENST00000326735.8:c.2281G>T p.Ala761Ser p.A761S ENST00000326735 761 Gcc/Tcc 0 +ATRX UCSF GRCh37 X 76938099 76938100 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 120 0 ENST00000373344.5:c.2648_2649del p.Gln883ArgfsTer13 p.Q883Rfs*13 ENST00000373344 NM_000489.3 883 cAA/c 0 +CDH2 UCSF GRCh37 18 25727679 25727679 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 54 28 81 0 ENST00000269141.3:c.130G>C p.Val44Leu p.V44L ENST00000269141 NM_001792.3 44 Gtc/Ctc 0 +CDKN2A UCSF GRCh37 9 21970993 21970993 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 8 0 ENST00000304494.5:c.365del p.Gly122AlafsTer24 p.G122Afs*24 ENST00000304494 NM_000077.4 122 gGc/gc 0 +CNTNAP2 UCSF GRCh37 7 147844772 147844772 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 52 24 57 0 ENST00000361727.3:c.2744G>A p.Arg915His p.R915H ENST00000361727 NM_014141.5 915 cGc/cAc 0 +CTNND2 UCSF GRCh37 5 11364832 11364832 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 29 20 49 0 ENST00000304623.8:c.1348A>G p.Thr450Ala p.T450A ENST00000304623 NM_001332.2 450 Acc/Gcc 0 +DHX34 UCSF GRCh37 19 47876868 47876868 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 30 16 43 0 ENST00000328771.4:c.1975C>T p.Arg659Trp p.R659W ENST00000328771 NM_014681.5 659 Cgg/Tgg 0 +DMWD UCSF GRCh37 19 46287928 46287928 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 74 46 142 0 ENST00000270223.6:c.1948C>T p.Pro650Ser p.P650S ENST00000270223 NM_004943.1 650 Ccc/Tcc 0 +DNAJC11 UCSF GRCh37 1 6700009 6700009 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 23 17 63 0 ENST00000377577.5:c.1206C>T p.Ala402= p.A402= ENST00000377577 NM_018198.3 402 gcC/gcT 0 +DUOXA2 UCSF GRCh37 15 45408389 45408389 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 168 101 307 0 ENST00000323030.5:c.273C>T p.Ser91= p.S91= ENST00000323030 NM_207581.3 91 agC/agT 0 +EYA2 UCSF GRCh37 20 45771717 45771717 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 104 78 170 0 ENST00000327619.5:c.908G>A p.Arg303His p.R303H ENST00000327619 NM_005244.4 303 cGc/cAc 0 +FLG UCSF GRCh37 1 152284325 152284325 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 24 16 47 0 ENST00000368799.1:c.3037T>C p.Ser1013Pro p.S1013P ENST00000368799 NM_002016.1 1013 Tcc/Ccc 0 +FMN2 UCSF GRCh37 1 240255560 240255560 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 60 48 85 0 ENST00000319653.9:c.151G>A p.Gly51Arg p.G51R ENST00000319653 NM_020066.4 51 Ggg/Agg 0 +GNE UCSF GRCh37 9 36217503 36217503 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 172 69 188 0 ENST00000396594.3:c.2121C>G p.Ile707Met p.I707M ENST00000396594 NM_001128227.2 707 atC/atG 0 +GNE UCSF GRCh37 9 36217533 36217533 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 166 61 171 0 ENST00000396594.3:c.2091C>G p.Ile697Met p.I697M ENST00000396594 NM_001128227.2 697 atC/atG 0 +GPR44 UCSF GRCh37 11 60620792 60620792 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 38 22 77 0 ENST00000332539.4:c.404G>A p.Arg135Gln p.R135Q ENST00000332539 NM_004778.2 135 cGg/cAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 12 11 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL11 UCSF GRCh37 19 55879672 55879672 + missense_variant Missense_Mutation SNP C C T 1000g2010nov_all_0.010,1000g2011may_all_0.0145,snp132_rs4252548 P27_Rec1_A Untested WXS Illumina HiSeq 15 12 31 0 ENST00000264563.2:c.335G>A p.Arg112His p.R112H ENST00000264563 NM_000641.3 112 cGc/cAc 0 +KATNB1 UCSF GRCh37 16 57787370 57787370 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 54 45 116 0 ENST00000379661.3:c.1116C>T p.Ser372= p.S372= ENST00000379661 NM_005886.2 372 tcC/tcT 0 +KRT12 UCSF GRCh37 17 39023245 39023246 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 129 0 ENST00000251643.4:c.194dup p.Ser66Ter p.S66* ENST00000251643 NM_000223.3 65 tct/tCct 0 +MUC6 UCSF GRCh37 11 1031684 1031684 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 83 48 158 0 ENST00000421673.2:c.406G>A p.Gly136Ser p.G136S ENST00000421673 NM_005961.2 136 Ggc/Agc 0 +MYO18A UCSF GRCh37 17 27437604 27437604 + synonymous_variant Silent SNP G G T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 57 8 53 0 ENST00000527372.1:c.2937C>A p.Gly979= p.G979= ENST00000527372 NM_078471.3 979 ggC/ggA 0 +MYO18B UCSF GRCh37 22 26159269 26159269 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 108 72 213 0 ENST00000335473.7:c.111C>T p.Phe37= p.F37= ENST00000335473 NM_032608.5 37 ttC/ttT 0 +NBPF1 UCSF GRCh37 1 16893813 16893813 + synonymous_variant Silent SNP A A G snp132_rs58611269 P27_Rec1_A Untested WXS Illumina HiSeq 15 3 19 0 ENST00000430580.2:c.2700T>C p.Pro900= p.P900= ENST00000430580 NM_017940.4 900 ccT/ccC 0 +OR10AG1 UCSF GRCh37 11 55735772 55735772 + missense_variant Missense_Mutation SNP A A T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 86 60 166 1 ENST00000312345.2:c.168T>A p.Asn56Lys p.N56K ENST00000312345 NM_001005491.1 56 aaT/aaA 0 +PRAMEF20 UCSF GRCh37 1 13743058 13743058 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.039,1000g2011may_all_0.0457,snp132_rs77164784 P27_Rec1_A Untested WXS Illumina HiSeq 15 3 17 0 ENST00000316412.5:c.247G>A p.Asp83Asn p.D83N ENST00000316412 NM_001099852.1 83 Gat/Aat 0 +PRB1 UCSF GRCh37 12 11506350 11506350 + intron_variant Intron SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 11 3 14 0 ENST00000500254.2:c.314-26G>A *105* ENST00000500254 NM_199353.2 0 +PRF1 UCSF GRCh37 10 72358862 72358862 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 48 39 107 0 ENST00000441259.1:c.615C>T p.Asn205= p.N205= ENST00000441259 NM_005041.4 205 aaC/aaT 0 +PRSS50 UCSF GRCh37 3 46753929 46753929 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 22 17 43 0 ENST00000460241.1:c.965G>T p.Trp322Leu p.W322L ENST00000460241 322 tGg/tTg 0 +PSKH2 UCSF GRCh37 8 87060758 87060758 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 80 51 160 0 ENST00000276616.2:c.1091A>G p.Lys364Arg p.K364R ENST00000276616 NM_033126.1 364 aAa/aGa 0 +SCN2A UCSF GRCh37 2 166237141 166237141 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 105 40 138 0 ENST00000357398.3:c.4348T>G p.Tyr1450Asp p.Y1450D ENST00000357398 1450 Tat/Gat 0 +SEMA4D UCSF GRCh37 9 92008491 92008491 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 28 32 76 0 ENST00000450295.1:c.494C>T p.Thr165Ile p.T165I ENST00000450295 165 aCa/aTa 0 +SLCO6A1 UCSF GRCh37 5 101735273 101735273 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 40 27 63 0 ENST00000506729.1:c.1800C>T p.Val600= p.V600= ENST00000506729 600 gtC/gtT 0 +SMARCA4 UCSF GRCh37 19 11141559 11141559 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Rec1_A somatic WXS Sanger Illumina HiSeq 17 5 36 0 ENST00000344626.4:c.3536A>G p.Asn1179Ser p.N1179S ENST00000344626 NM_003072.3 1179 aAt/aGt 0 +SPHKAP UCSF GRCh37 2 228883637 228883637 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 105 89 199 0 ENST00000392056.3:c.1933A>G p.Arg645Gly p.R645G ENST00000392056 NM_001142644.1 645 Agg/Ggg 0 +ST18 UCSF GRCh37 8 53084929 53084929 + synonymous_variant Silent SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 140 72 230 1 ENST00000276480.7:c.492A>G p.Ala164= p.A164= ENST00000276480 NM_014682.2 164 gcA/gcG 0 +STAT4 UCSF GRCh37 2 191937835 191937835 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 203 139 466 0 ENST00000392320.2:c.454A>G p.Asn152Asp p.N152D ENST00000392320 NM_003151.3 152 Aac/Gac 0 +STYK1 UCSF GRCh37 12 10780287 10780287 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 184 112 300 0 ENST00000075503.3:c.670A>G p.Thr224Ala p.T224A ENST00000075503 NM_018423.2 224 Aca/Gca 0 +TH1L UCSF GRCh37 20 57569284 57569284 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 96 54 169 0 ENST00000602795.1:c.1755G>A p.Thr585= p.T585= ENST00000602795 NM_198976.2 585 acG/acA 0 +TMEM95 UCSF GRCh37 17 7258580 7258580 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 56 41 118 0 ENST00000330767.4:c.57C>T p.Phe19= p.F19= ENST00000330767 NM_198154.1 19 ttC/ttT 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 12 56 71 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +WDR62 UCSF GRCh37 19 36585008 36585008 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 73 58 166 0 ENST00000401500.2:c.2409G>A p.Glu803= p.E803= ENST00000401500 NM_001083961.1 803 gaG/gaA 0 +XKRX UCSF GRCh37 X 100169574 100169574 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 70 186 249 0 ENST00000372956.2:c.1103A>C p.Lys368Thr p.K368T ENST00000372956 368 aAg/aCg 0 +ZKSCAN4 UCSF GRCh37 6 28213206 28213206 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 316 209 579 0 ENST00000377294.2:c.1326G>C p.Arg442Ser p.R442S ENST00000377294 NM_019110.3 442 agG/agC 0 +ZSWIM5 UCSF GRCh37 1 45516885 45516885 + synonymous_variant Silent SNP T T C NOVEL P27_Rec1_A Untested WXS Illumina HiSeq 74 41 186 0 ENST00000359600.5:c.1293A>G p.Lys431= p.K431= ENST00000359600 NM_020883.1 431 aaA/aaG 0 +AKR1D1 UCSF GRCh37 7 137791441 137791441 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 168 58 221 0 ENST00000242375.3:c.667G>C p.Gly223Arg p.G223R ENST00000242375 NM_005989.3 223 Ggg/Cgg 0 +AMIGO1 UCSF GRCh37 1 110051079 110051079 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 86 41 207 0 ENST00000369864.4:c.456C>T p.Cys152= p.C152= ENST00000369864 152 tgC/tgT 0 +ATRX UCSF GRCh37 X 76938099 76938100 + frameshift_variant Frame_Shift_Del DEL TT TT - NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 87 0 ENST00000373344.5:c.2648_2649del p.Gln883ArgfsTer13 p.Q883Rfs*13 ENST00000373344 NM_000489.3 883 cAA/c 0 +CDH2 UCSF GRCh37 18 25727679 25727679 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 57 16 81 0 ENST00000269141.3:c.130G>C p.Val44Leu p.V44L ENST00000269141 NM_001792.3 44 Gtc/Ctc 0 +CDKN2A UCSF GRCh37 9 21970993 21970993 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 23 0 ENST00000304494.5:c.365del p.Gly122AlafsTer24 p.G122Afs*24 ENST00000304494 NM_000077.4 122 gGc/gc 0 +CNTNAP2 UCSF GRCh37 7 147844772 147844772 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 36 20 57 0 ENST00000361727.3:c.2744G>A p.Arg915His p.R915H ENST00000361727 NM_014141.5 915 cGc/cAc 0 +CTNND2 UCSF GRCh37 5 11364832 11364832 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 14 15 49 0 ENST00000304623.8:c.1348A>G p.Thr450Ala p.T450A ENST00000304623 NM_001332.2 450 Acc/Gcc 0 +DHX34 UCSF GRCh37 19 47876868 47876868 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 24 13 43 0 ENST00000328771.4:c.1975C>T p.Arg659Trp p.R659W ENST00000328771 NM_014681.5 659 Cgg/Tgg 0 +DMWD UCSF GRCh37 19 46287928 46287928 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 58 40 142 0 ENST00000270223.6:c.1948C>T p.Pro650Ser p.P650S ENST00000270223 NM_004943.1 650 Ccc/Tcc 0 +DNAJC11 UCSF GRCh37 1 6700009 6700009 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 29 21 63 0 ENST00000377577.5:c.1206C>T p.Ala402= p.A402= ENST00000377577 NM_018198.3 402 gcC/gcT 0 +DUOXA2 UCSF GRCh37 15 45408389 45408389 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 101 49 307 0 ENST00000323030.5:c.273C>T p.Ser91= p.S91= ENST00000323030 NM_207581.3 91 agC/agT 0 +EYA2 UCSF GRCh37 20 45771717 45771717 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 121 37 170 0 ENST00000327619.5:c.908G>A p.Arg303His p.R303H ENST00000327619 NM_005244.4 303 cGc/cAc 0 +FLG UCSF GRCh37 1 152284325 152284325 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 19 15 47 0 ENST00000368799.1:c.3037T>C p.Ser1013Pro p.S1013P ENST00000368799 NM_002016.1 1013 Tcc/Ccc 0 +FMN2 UCSF GRCh37 1 240255560 240255560 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 34 24 85 0 ENST00000319653.9:c.151G>A p.Gly51Arg p.G51R ENST00000319653 NM_020066.4 51 Ggg/Agg 0 +GNE UCSF GRCh37 9 36217503 36217503 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 158 38 188 0 ENST00000396594.3:c.2121C>G p.Ile707Met p.I707M ENST00000396594 NM_001128227.2 707 atC/atG 0 +GNE UCSF GRCh37 9 36217533 36217533 + missense_variant Missense_Mutation SNP G G C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 154 35 171 0 ENST00000396594.3:c.2091C>G p.Ile697Met p.I697M ENST00000396594 NM_001128227.2 697 atC/atG 0 +GPR44 UCSF GRCh37 11 60620792 60620792 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 31 11 77 0 ENST00000332539.4:c.404G>A p.Arg135Gln p.R135Q ENST00000332539 NM_004778.2 135 cGg/cAg 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 9 20 35 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KATNB1 UCSF GRCh37 16 57787370 57787370 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 42 20 116 0 ENST00000379661.3:c.1116C>T p.Ser372= p.S372= ENST00000379661 NM_005886.2 372 tcC/tcT 0 +KRT12 UCSF GRCh37 17 39023245 39023246 + frameshift_variant Frame_Shift_Ins INS - - G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 70 0 ENST00000251643.4:c.194dup p.Ser66Ter p.S66* ENST00000251643 NM_000223.3 65 tct/tCct 0 +MUC6 UCSF GRCh37 11 1031684 1031684 + missense_variant Missense_Mutation SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 60 24 158 0 ENST00000421673.2:c.406G>A p.Gly136Ser p.G136S ENST00000421673 NM_005961.2 136 Ggc/Agc 0 +MYO18B UCSF GRCh37 22 26159269 26159269 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 67 46 213 0 ENST00000335473.7:c.111C>T p.Phe37= p.F37= ENST00000335473 NM_032608.5 37 ttC/ttT 0 +OR10AG1 UCSF GRCh37 11 55735772 55735772 + missense_variant Missense_Mutation SNP A A T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 78 65 166 1 ENST00000312345.2:c.168T>A p.Asn56Lys p.N56K ENST00000312345 NM_001005491.1 56 aaT/aaA 0 +PRF1 UCSF GRCh37 10 72358862 72358862 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 35 20 107 0 ENST00000441259.1:c.615C>T p.Asn205= p.N205= ENST00000441259 NM_005041.4 205 aaC/aaT 0 +PRSS50 UCSF GRCh37 3 46753929 46753929 + missense_variant Missense_Mutation SNP C C A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 12 14 43 0 ENST00000460241.1:c.965G>T p.Trp322Leu p.W322L ENST00000460241 322 tGg/tTg 0 +PSKH2 UCSF GRCh37 8 87060758 87060758 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 62 35 160 0 ENST00000276616.2:c.1091A>G p.Lys364Arg p.K364R ENST00000276616 NM_033126.1 364 aAa/aGa 0 +SCN2A UCSF GRCh37 2 166237141 166237141 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 95 34 138 0 ENST00000357398.3:c.4348T>G p.Tyr1450Asp p.Y1450D ENST00000357398 1450 Tat/Gat 0 +SEMA4D UCSF GRCh37 9 92008491 92008491 + missense_variant Missense_Mutation SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 31 28 76 0 ENST00000450295.1:c.494C>T p.Thr165Ile p.T165I ENST00000450295 165 aCa/aTa 0 +SLCO6A1 UCSF GRCh37 5 101735273 101735273 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 45 26 63 0 ENST00000506729.1:c.1800C>T p.Val600= p.V600= ENST00000506729 600 gtC/gtT 0 +SMARCA4 UCSF GRCh37 19 11141559 11141559 + missense_variant Missense_Mutation SNP A A G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 13 9 36 0 ENST00000344626.4:c.3536A>G p.Asn1179Ser p.N1179S ENST00000344626 NM_003072.3 1179 aAt/aGt 0 +SPHKAP UCSF GRCh37 2 228883637 228883637 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 122 66 199 0 ENST00000392056.3:c.1933A>G p.Arg645Gly p.R645G ENST00000392056 NM_001142644.1 645 Agg/Ggg 0 +ST18 UCSF GRCh37 8 53084929 53084929 + synonymous_variant Silent SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 131 48 230 1 ENST00000276480.7:c.492A>G p.Ala164= p.A164= ENST00000276480 NM_014682.2 164 gcA/gcG 0 +STAT4 UCSF GRCh37 2 191937835 191937835 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 212 86 466 0 ENST00000392320.2:c.454A>G p.Asn152Asp p.N152D ENST00000392320 NM_003151.3 152 Aac/Gac 0 +STYK1 UCSF GRCh37 12 10780287 10780287 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 165 68 300 0 ENST00000075503.3:c.670A>G p.Thr224Ala p.T224A ENST00000075503 NM_018423.2 224 Aca/Gca 0 +TH1L UCSF GRCh37 20 57569284 57569284 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 62 20 169 0 ENST00000602795.1:c.1755G>A p.Thr585= p.T585= ENST00000602795 NM_198976.2 585 acG/acA 0 +TMEM95 UCSF GRCh37 17 7258580 7258580 + synonymous_variant Silent SNP C C T NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 44 29 118 0 ENST00000330767.4:c.57C>T p.Phe19= p.F19= ENST00000330767 NM_198154.1 19 ttC/ttT 0 +TP53 UCSF GRCh37 17 7578190 7578190 + missense_variant Missense_Mutation SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 5 29 71 0 ENST00000269305.4:c.659A>G p.Tyr220Cys p.Y220C ENST00000269305 NM_001126112.2 220 tAt/tGt 0 +WDR62 UCSF GRCh37 19 36585008 36585008 + synonymous_variant Silent SNP G G A NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 83 57 166 0 ENST00000401500.2:c.2409G>A p.Glu803= p.E803= ENST00000401500 NM_001083961.1 803 gaG/gaA 0 +XKRX UCSF GRCh37 X 100169574 100169574 + missense_variant Missense_Mutation SNP T T G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 68 136 249 0 ENST00000372956.2:c.1103A>C p.Lys368Thr p.K368T ENST00000372956 368 aAg/aCg 0 +ZKSCAN4 UCSF GRCh37 6 28213206 28213206 + missense_variant Missense_Mutation SNP C C G NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 218 149 579 0 ENST00000377294.2:c.1326G>C p.Arg442Ser p.R442S ENST00000377294 NM_019110.3 442 agG/agC 0 +ZSWIM5 UCSF GRCh37 1 45516885 45516885 + synonymous_variant Silent SNP T T C NOVEL P27_Rec1_B Untested WXS Illumina HiSeq 42 48 186 0 ENST00000359600.5:c.1293A>G p.Lys431= p.K431= ENST00000359600 NM_020883.1 431 aaA/aaG 0 +AMPD1 UCSF GRCh37 1 115222309 115222309 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Pri Untested WXS Illumina HiSeq 53 37 81 0 ENST00000520113.2:c.887G>A p.Arg296His p.R296H ENST00000520113 296 cGc/cAc 0 +AMZ2 UCSF GRCh37 17 66250631 66250631 + missense_variant Missense_Mutation SNP T T C NOVEL P28_Pri Untested WXS Illumina HiSeq 114 47 171 0 ENST00000359904.3:c.673T>C p.Ser225Pro p.S225P ENST00000359904 NM_016627.4 225 Tct/Cct 0 +ARSI UCSF GRCh37 5 149677736 149677736 + missense_variant Missense_Mutation SNP G G A NOVEL P28_Pri Untested WXS Illumina HiSeq 97 60 145 0 ENST00000328668.7:c.751C>T p.Arg251Cys p.R251C ENST00000328668 NM_001012301.2 251 Cgc/Tgc 0 +ATRX UCSF GRCh37 X 76937611 76937615 + frameshift_variant Frame_Shift_Del DEL CTTTT CTTTT - NOVEL P28_Pri Untested WXS Illumina HiSeq 180 0 ENST00000373344.5:c.3133_3137delAAAAG p.Lys1045Ter p.K1045* ENST00000373344 NM_000489.3 1045 AAAAGt/t 0 +C20orf96(NM_080571:exon2:c.17+2->TA) UCSF GRCh37 20 271226 271227 + splice_region_variant,intron_variant Splice_Region INS - - TA NOVEL P28_Pri Untested WXS Illumina HiSeq 7 0 ENST00000360321.2:c.20+6_20+7dup p.X7_splice ENST00000360321 NM_153269.2 0 +CYB5D2 UCSF GRCh37 17 4053185 4053185 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P28_Pri Untested WXS Illumina HiSeq 30 10 50 0 ENST00000301391.3:c.251G>A p.Gly84Asp p.G84D ENST00000301391 NM_144611.3 84 gGc/gAc 0 +FLG UCSF GRCh37 1 152284806 152284806 + synonymous_variant Silent SNP C C T snp132_rs71625190 P28_Pri Untested WXS Illumina HiSeq 16 7 15 1 ENST00000368799.1:c.2556G>A p.Arg852= p.R852= ENST00000368799 NM_002016.1 852 agG/agA 0 +FZR1 UCSF GRCh37 19 3533340 3533340 + missense_variant Missense_Mutation SNP C C G NOVEL P28_Pri Untested WXS Illumina HiSeq 83 12 72 0 ENST00000395095.3:c.1291C>G p.Pro431Ala p.P431A ENST00000395095 NM_001136198.1 431 Ccc/Gcc 0 +GPR98 UCSF GRCh37 5 90085648 90085648 + missense_variant Missense_Mutation SNP G G A NOVEL P28_Pri Untested WXS Illumina HiSeq 29 18 41 0 ENST00000405460.2:c.14023G>A p.Gly4675Ser p.G4675S ENST00000405460 NM_032119.3 4675 Ggc/Agc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Pri Untested WXS Illumina HiSeq 13 13 24 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +KRTAP4-9 UCSF GRCh37 17 39261693 39261693 + missense_variant Missense_Mutation SNP A A T 1000g2010nov_all_0.281,snp132_rs113059833 P28_Pri Untested WXS Illumina HiSeq 32 5 41 0 ENST00000391415.1:c.53A>T p.Asp18Val p.D18V ENST00000391415 NM_001146041.1 18 gAc/gTc 0 +LOXHD1 UCSF GRCh37 18 44152078 44152078 + missense_variant Missense_Mutation SNP A A G NOVEL P28_Pri Untested WXS Illumina HiSeq 107 64 165 0 ENST00000398722.4:c.1184T>C p.Leu395Pro p.L395P ENST00000398722 395 cTa/cCa 0 +MICAL2 UCSF GRCh37 11 12263921 12263921 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Pri Untested WXS Illumina HiSeq 99 56 138 0 ENST00000256194.4:c.2498C>T p.Ala833Val p.A833V ENST00000256194 NM_014632.2 833 gCg/gTg 0 +MLL3 UCSF GRCh37 7 151945313 151945313 + synonymous_variant Silent SNP A A G NOVEL P28_Pri Untested WXS Illumina HiSeq 22 3 22 1 ENST00000262189.6:c.2206T>C p.Leu736= p.L736= ENST00000262189 NM_170606.2 736 Ttg/Ctg 0 +PKP2 UCSF GRCh37 12 33031211 33031211 + synonymous_variant Silent SNP C C T NOVEL P28_Pri Untested WXS Illumina HiSeq 76 63 153 0 ENST00000070846.6:c.603G>A p.Gly201= p.G201= ENST00000070846 NM_004572.3 201 ggG/ggA 0 +RAPGEF4 UCSF GRCh37 2 173679042 173679042 + synonymous_variant Silent SNP G G A NOVEL P28_Pri Untested WXS Illumina HiSeq 204 147 299 1 ENST00000397081.3:c.333G>A p.Thr111= p.T111= ENST00000397081 NM_007023.3 111 acG/acA 0 +SLC18A2 UCSF GRCh37 10 119026521 119026521 + missense_variant Missense_Mutation SNP T T C NOVEL P28_Pri Untested WXS Illumina HiSeq 117 75 190 0 ENST00000298472.5:c.1097T>C p.Ile366Thr p.I366T ENST00000298472 NM_003054.4 366 aTa/aCa 0 +SPATA5 UCSF GRCh37 4 123848842 123848842 + missense_variant Missense_Mutation SNP A A T NOVEL P28_Pri Untested WXS Illumina HiSeq 168 123 296 0 ENST00000274008.4:c.217A>T p.Asn73Tyr p.N73Y ENST00000274008 NM_145207.2 73 Aac/Tac 0 +THAP5 UCSF GRCh37 7 108205526 108205526 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P28_Pri Untested WXS Illumina HiSeq 7 0 ENST00000415914.3:c.297delA p.Lys99AsnfsTer25 p.K99Nfs*25 ENST00000415914 NM_001130475.1 99 aaA/aa 0 +TP53 UCSF GRCh37 17 7578541 7578541 + missense_variant Missense_Mutation SNP A A C NOVEL P28_Pri Untested WXS Illumina HiSeq 11 63 74 0 ENST00000269305.4:c.389T>G p.Leu130Arg p.L130R ENST00000269305 NM_001126112.2 130 cTc/cGc 0 +AMPD1 UCSF GRCh37 1 115222309 115222309 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 48 36 81 0 ENST00000520113.2:c.887G>A p.Arg296His p.R296H ENST00000520113 296 cGc/cAc 0 +AMZ2 UCSF GRCh37 17 66250631 66250631 + missense_variant Missense_Mutation SNP T T C NOVEL P28_Rec Untested WXS Illumina HiSeq 148 76 171 0 ENST00000359904.3:c.673T>C p.Ser225Pro p.S225P ENST00000359904 NM_016627.4 225 Tct/Cct 0 +ARSI UCSF GRCh37 5 149677736 149677736 + missense_variant Missense_Mutation SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 81 76 145 0 ENST00000328668.7:c.751C>T p.Arg251Cys p.R251C ENST00000328668 NM_001012301.2 251 Cgc/Tgc 0 +ATRX UCSF GRCh37 X 76937611 76937615 + frameshift_variant Frame_Shift_Del DEL CTTTT CTTTT - NOVEL P28_Rec Untested WXS Illumina HiSeq 198 0 ENST00000373344.5:c.3133_3137delAAAAG p.Lys1045Ter p.K1045* ENST00000373344 NM_000489.3 1045 AAAAGt/t 0 +CPNE2 UCSF GRCh37 16 57180218 57180218 + synonymous_variant Silent SNP T T C NOVEL P28_Rec Untested WXS Illumina HiSeq 254 29 189 0 ENST00000535318.2:c.1524T>C p.Phe508= p.F508= ENST00000535318 508 ttT/ttC 0 +CYB5D2 UCSF GRCh37 17 4053185 4053185 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 28 27 50 0 ENST00000301391.3:c.251G>A p.Gly84Asp p.G84D ENST00000301391 NM_144611.3 84 gGc/gAc 0 +DENND2D UCSF GRCh37 1 111741364 111741364 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 85 10 87 0 ENST00000357640.4:c.244C>T p.Arg82Trp p.R82W ENST00000357640 NM_024901.4 82 Cgg/Tgg 0 +DNMT1 UCSF GRCh37 19 10262139 10262139 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P28_Rec Untested WXS Illumina HiSeq 8 0 ENST00000340748.4:c.2152delA p.Met718CysfsTer59 p.M718Cfs*59 ENST00000340748 718 Atg/tg 0 +FZR1 UCSF GRCh37 19 3533340 3533340 + missense_variant Missense_Mutation SNP C C G NOVEL P28_Rec Untested WXS Illumina HiSeq 107 30 72 0 ENST00000395095.3:c.1291C>G p.Pro431Ala p.P431A ENST00000395095 NM_001136198.1 431 Ccc/Gcc 0 +GCN1L1 UCSF GRCh37 12 120612953 120612984 + splice_donor_variant,coding_sequence_variant,intron_variant Splice_Site DEL GAAATCCTATACCTGAGAGGACGCTCATCTTC GAAATCCTATACCTGAGAGGACGCTCATCTTC AAATCCTATACCTGGGAGGACGCTCATCTTT NOVEL P28_Rec Untested WXS Illumina HiSeq 7 0 ENST00000300648.6:c.1074_1093+12delinsAAAGATGAGCGTCCTCCCAGGTATAGGATTT p.X358_splice ENST00000300648 NM_006836.1 358 0 +GPR98 UCSF GRCh37 5 90085648 90085648 + missense_variant Missense_Mutation SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 31 18 41 0 ENST00000405460.2:c.14023G>A p.Gly4675Ser p.G4675S ENST00000405460 NM_032119.3 4675 Ggc/Agc 0 +HNRNPCL1 UCSF GRCh37 1 12907762 12907762 + synonymous_variant Silent SNP T T C 1000g2010nov_all_0.028,1000g2011may_all_0.0727,snp132_rs57026768 P28_Rec Untested WXS Illumina HiSeq 16 4 23 1 ENST00000317869.6:c.381A>G p.Pro127= p.P127= ENST00000317869 NM_001013631.1 127 ccA/ccG 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 8 16 24 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +LOXHD1 UCSF GRCh37 18 44152078 44152078 + missense_variant Missense_Mutation SNP A A G NOVEL P28_Rec Untested WXS Illumina HiSeq 96 72 165 0 ENST00000398722.4:c.1184T>C p.Leu395Pro p.L395P ENST00000398722 395 cTa/cCa 0 +MCM7 UCSF GRCh37 7 99697025 99697041 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL ACCTAAAGGAGAAGAAC ACCTAAAGGAGAAGAAC CCCAAAAGGAAAAAAA NOVEL P28_Rec Untested WXS Illumina HiSeq 6 0 ENST00000303887.5:c.277-15_278delinsTTTTTTTCCTTTTGGG p.X93_splice ENST00000303887 NM_001278595.1 0 +MICAL2 UCSF GRCh37 11 12263921 12263921 + missense_variant Missense_Mutation SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 98 51 138 0 ENST00000256194.4:c.2498C>T p.Ala833Val p.A833V ENST00000256194 NM_014632.2 833 gCg/gTg 0 +NMT2 UCSF GRCh37 10 15172208 15172208 + missense_variant Missense_Mutation SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 17 3 19 0 ENST00000378165.4:c.823C>A p.Leu275Met p.L275M ENST00000378165 NM_004808.2 275 Ctg/Atg 0 +PKP2 UCSF GRCh37 12 33031211 33031211 + synonymous_variant Silent SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 92 63 153 0 ENST00000070846.6:c.603G>A p.Gly201= p.G201= ENST00000070846 NM_004572.3 201 ggG/ggA 0 +POLA1 UCSF GRCh37 X 24833131 24833131 + missense_variant Missense_Mutation SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 21 3 23 0 ENST00000379059.3:c.3314G>T p.Arg1105Leu p.R1105L ENST00000379059 NM_016937.3 1105 cGg/cTg 0 +POLR3B UCSF GRCh37 12 106820973 106820987 + splice_acceptor_variant,coding_sequence_variant Splice_Site INS AGCTTTTATCTCTTC AGCTTTTATCTCTTC TAGCTTTTTTCTTTTT NOVEL P28_Rec Untested WXS Illumina HiSeq 6 0 ENST00000228347.4:c.1102-2_1114delinsTAGCTTTTTTCTTTTT p.X368_splice ENST00000228347 NM_018082.5 0 +RAPGEF4 UCSF GRCh37 2 173679042 173679042 + synonymous_variant Silent SNP G G A NOVEL P28_Rec Untested WXS Illumina HiSeq 202 158 299 1 ENST00000397081.3:c.333G>A p.Thr111= p.T111= ENST00000397081 NM_007023.3 111 acG/acA 0 +RHPN1 UCSF GRCh37 8 144460938 144460938 + synonymous_variant Silent SNP C C T NOVEL P28_Rec Untested WXS Illumina HiSeq 228 381 370 0 ENST00000289013.6:c.532C>T p.Leu178= p.L178= ENST00000289013 NM_052924.2 178 Ctg/Ttg 0 +RPL18 UCSF GRCh37 19 49119149 49119149 + missense_variant Missense_Mutation SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 24 3 42 0 ENST00000549920.1:c.476C>A p.Pro159Gln p.P159Q ENST00000549920 NM_000979.3 159 cCg/cAg 0 +SDK1 UCSF GRCh37 7 4304761 4304761 + synonymous_variant Silent SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 25 3 45 0 ENST00000404826.2:c.6387G>T p.Thr2129= p.T2129= ENST00000404826 NM_152744.3 2129 acG/acT 0 +SERPINB3 UCSF GRCh37 18 61326651 61326651 + synonymous_variant Silent SNP T T C NOVEL P28_Rec Untested WXS Illumina HiSeq 26 9 50 0 ENST00000283752.5:c.333A>G p.Lys111= p.K111= ENST00000283752 NM_006919.2 111 aaA/aaG 0 +SERPINI1 UCSF GRCh37 3 167508159 167508159 + splice_acceptor_variant Splice_Site SNP G G T NOVEL P28_Rec Untested WXS Illumina HiSeq 35 4 51 0 ENST00000295777.5:c.251-1G>T p.X84_splice ENST00000295777 NM_005025.4 0 +SLC18A2 UCSF GRCh37 10 119026521 119026521 + missense_variant Missense_Mutation SNP T T C NOVEL P28_Rec Untested WXS Illumina HiSeq 91 86 190 0 ENST00000298472.5:c.1097T>C p.Ile366Thr p.I366T ENST00000298472 NM_003054.4 366 aTa/aCa 0 +SPATA5 UCSF GRCh37 4 123848842 123848842 + missense_variant Missense_Mutation SNP A A T NOVEL P28_Rec Untested WXS Illumina HiSeq 180 146 296 0 ENST00000274008.4:c.217A>T p.Asn73Tyr p.N73Y ENST00000274008 NM_145207.2 73 Aac/Tac 0 +TCEAL3 UCSF GRCh37 X 102864442 102864442 + synonymous_variant Silent SNP A A G 1000g2010nov_all_0.02464 P28_Rec Untested WXS Illumina HiSeq 12 5 12 0 ENST00000372628.1:c.450A>G p.Gln150= p.Q150= ENST00000372628 150 caA/caG 0 +TP53 UCSF GRCh37 17 7578541 7578541 + missense_variant Missense_Mutation SNP A A C NOVEL P28_Rec Untested WXS Illumina HiSeq 7 94 74 0 ENST00000269305.4:c.389T>G p.Leu130Arg p.L130R ENST00000269305 NM_001126112.2 130 cTc/cGc 0 +ADNP UCSF GRCh37 20 49508204 49508204 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P29_Pri Untested WXS Illumina HiSeq 7 0 ENST00000396029.3:c.3047delA p.Lys1016ArgfsTer11 p.K1016Rfs*11 ENST00000396029 NM_015339.2 1016 aAg/ag 0 +AP2A1 UCSF GRCh37 19 50306222 50306222 + missense_variant Missense_Mutation SNP A A G NOVEL P29_Pri Untested WXS Illumina HiSeq 13 21 25 0 ENST00000359032.5:c.2197A>G p.Ile733Val p.I733V ENST00000359032 NM_014203.2 733 Atc/Gtc 0 +ATRX UCSF GRCh37 X 76813051 76813084 + frameshift_variant Frame_Shift_Del DEL AACAACTCGAAAAGACAGTGACTGCTTAGTTACT AACAACTCGAAAAGACAGTGACTGCTTAGTTACT - NOVEL P29_Pri Untested WXS Illumina HiSeq 33 0 ENST00000373344.5:c.6537_6570del p.Val2180IlefsTer11 p.V2180Ifs*11 ENST00000373344 NM_000489.3 2179 caAGTAACTAAGCAGTCACTGTCTTTTCGAGTTGTT/ca 0 +CAPN9 UCSF GRCh37 1 230903389 230903389 + synonymous_variant Silent SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 132 87 236 0 ENST00000271971.2:c.639C>T p.Pro213= p.P213= ENST00000271971 NM_006615.2 213 ccC/ccT 0 +CDC25B UCSF GRCh37 20 3785568 3785568 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 140 262 248 0 ENST00000245960.5:c.1703G>A p.Arg568Gln p.R568Q ENST00000245960 NM_021873.2 568 cGg/cAg 0 +COL4A4 UCSF GRCh37 2 227966580 227966580 + splice_donor_variant Splice_Site SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 83 45 138 0 ENST00000396625.3:c.975+1G>A p.X325_splice ENST00000396625 NM_000092.4 0 +CUX1 UCSF GRCh37 7 101892124 101892124 + synonymous_variant Silent SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 36 5 38 0 ENST00000360264.3:c.4353G>A p.Pro1451= p.P1451= ENST00000360264 NM_001202543.1 1451 ccG/ccA 0 +DNAH5 UCSF GRCh37 5 13830849 13830849 + missense_variant Missense_Mutation SNP C C A NOVEL P29_Pri Untested WXS Illumina HiSeq 139 102 228 0 ENST00000265104.4:c.5918G>T p.Ser1973Ile p.S1973I ENST00000265104 NM_001369.2 1973 aGc/aTc 0 +DND1 UCSF GRCh37 5 140052430 140052430 + missense_variant Missense_Mutation SNP G G T 1000g2010nov_all_0.231,snp132_rs112925426 P29_Pri Untested WXS Illumina HiSeq 36 4 29 0 ENST00000542735.1:c.204C>A p.Asp68Glu p.D68E ENST00000542735 NM_194249.2 68 gaC/gaA 0 +DND1 UCSF GRCh37 5 140052424 140052424 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.301,snp132_rs72800921 P29_Pri Untested WXS Illumina HiSeq 35 4 27 1 ENST00000542735.1:c.210C>T p.Tyr70= p.Y70= ENST00000542735 NM_194249.2 70 taC/taT 0 +DPP6 UCSF GRCh37 7 153749963 153749963 + missense_variant Missense_Mutation SNP G G A snp132_rs2533731 P29_Pri Untested WXS Illumina HiSeq 17 4 9 0 ENST00000377770.3:c.58G>A p.Ala20Thr p.A20T ENST00000377770 20 Gcg/Acg 0 +EFTUD2 UCSF GRCh37 17 42937310 42937310 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 19 19 46 0 ENST00000426333.2:c.1823G>A p.Arg608His p.R608H ENST00000426333 NM_001142605.1 608 cGc/cAc 0 +EPHA8 UCSF GRCh37 1 22903034 22903034 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 164 164 301 0 ENST00000166244.3:c.484C>T p.Arg162Trp p.R162W ENST00000166244 NM_020526.3 162 Cgg/Tgg 0 +FAM114A1 UCSF GRCh37 4 38916617 38916617 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 119 64 205 0 ENST00000358869.2:c.868G>A p.Gly290Arg p.G290R ENST00000358869 NM_138389.2 290 Ggg/Agg 0 +FAM83H UCSF GRCh37 8 144808239 144808239 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 372 136 319 0 ENST00000388913.3:c.3392G>A p.Arg1131His p.R1131H ENST00000388913 NM_198488.3 1131 cGc/cAc 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 11 18 20 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL1RL2 UCSF GRCh37 2 102851729 102851729 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 58 54 137 0 ENST00000264257.2:c.1670G>A p.Arg557His p.R557H ENST00000264257 NM_003854.2 557 cGc/cAc 0 +INTS1 UCSF GRCh37 7 1539622 1539622 + synonymous_variant Silent SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 69 62 151 0 ENST00000404767.3:c.582C>T p.Ile194= p.I194= ENST00000404767 NM_001080453.2 194 atC/atT 0 +KCND1 UCSF GRCh37 X 48826075 48826075 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 17 66 92 0 ENST00000218176.3:c.604G>A p.Ala202Thr p.A202T ENST00000218176 NM_004979.4 202 Gcc/Acc 0 +KEL UCSF GRCh37 7 142650990 142650990 + synonymous_variant Silent SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 286 105 275 0 ENST00000355265.2:c.978G>A p.Pro326= p.P326= ENST00000355265 NM_000420.2 326 ccG/ccA 0 +KIAA1267 UCSF GRCh37 17 44249468 44249469 + protein_altering_variant In_Frame_Ins INS - - TGA NOVEL P29_Pri Untested WXS Illumina HiSeq 31 0 ENST00000262419.6:c.41_42insTCA p.Glu14delinsAspGln p.E14delinsDQ ENST00000262419 NM_001193466.1 14 gaa/gaTCAa 0 +KRT15 UCSF GRCh37 17 39673204 39673204 + missense_variant Missense_Mutation SNP C C A NOVEL P29_Pri Untested WXS Illumina HiSeq 34 31 67 0 ENST00000254043.3:c.594G>T p.Glu198Asp p.E198D ENST00000254043 NM_002275.3 198 gaG/gaT 0 +LAMB1 UCSF GRCh37 7 107626783 107626783 + missense_variant Missense_Mutation SNP A A T NOVEL P29_Pri Untested WXS Illumina HiSeq 182 120 291 0 ENST00000222399.6:c.449T>A p.Ile150Lys p.I150K ENST00000222399 NM_002291.2 150 aTa/aAa 0 +MEIS2 UCSF GRCh37 15 37376018 37376018 + synonymous_variant Silent SNP G G C NOVEL P29_Pri Untested WXS Illumina HiSeq 104 61 130 0 ENST00000561208.1:c.708C>G p.Ser236= p.S236= ENST00000561208 236 tcC/tcG 0 +MRVI1 UCSF GRCh37 11 10625991 10625991 + missense_variant Missense_Mutation SNP G G C NOVEL P29_Pri Untested WXS Illumina HiSeq 25 14 39 0 ENST00000423302.2:c.1704C>G p.Asn568Lys p.N568K ENST00000423302 NM_130385.3 568 aaC/aaG 0 +OR7C1 UCSF GRCh37 19 14910208 14910208 + synonymous_variant Silent SNP C C A NOVEL P29_Pri Untested WXS Illumina HiSeq 88 57 173 0 ENST00000248073.2:c.741G>T p.Val247= p.V247= ENST00000248073 NM_198944.1 247 gtG/gtT 0 +PIK3CG UCSF GRCh37 7 106509501 106509501 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 197 143 383 0 ENST00000359195.3:c.1495G>A p.Ala499Thr p.A499T ENST00000359195 NM_002649.2 499 Gct/Act 0 +POLL UCSF GRCh37 10 103345866 103345866 + stop_gained Nonsense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 17 11 27 0 ENST00000370162.3:c.163C>T p.Arg55Ter p.R55* ENST00000370162 NM_001174084.1 55 Cga/Tga 0 +POLR1A UCSF GRCh37 2 86260786 86260786 + missense_variant,splice_region_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 1 15 22 0 ENST00000263857.6:c.4159C>T p.Arg1387Trp p.R1387W ENST00000263857 1387 Cgg/Tgg 0 +PSMD13 UCSF GRCh37 11 251848 251848 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Pri Untested WXS Illumina HiSeq 69 48 122 0 ENST00000431206.2:c.953C>T p.Ser318Leu p.S318L ENST00000431206 NM_175932.2 318 tCg/tTg 0 +RETNLB UCSF GRCh37 3 108474653 108474653 + missense_variant Missense_Mutation SNP G G T NOVEL P29_Pri Untested WXS Illumina HiSeq 107 45 152 0 ENST00000295755.6:c.308C>A p.Thr103Asn p.T103N ENST00000295755 NM_032579.2 103 aCc/aAc 0 +RIN3 UCSF GRCh37 14 93118725 93118725 + missense_variant Missense_Mutation SNP A A G NOVEL P29_Pri Untested WXS Illumina HiSeq 36 29 68 0 ENST00000216487.7:c.1331A>G p.His444Arg p.H444R ENST00000216487 NM_024832.3 444 cAc/cGc 0 +RNF167 UCSF GRCh37 17 4846190 4846190 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 17 182 216 0 ENST00000262482.6:c.424G>A p.Glu142Lys p.E142K ENST00000262482 NM_015528.1 142 Gag/Aag 0 +RYK UCSF GRCh37 3 133928607 133928607 + missense_variant Missense_Mutation SNP T T C NOVEL P29_Pri Untested WXS Illumina HiSeq 77 44 113 0 ENST00000296084.4:c.515A>G p.Asn172Ser p.N172S ENST00000296084 NM_001005861.2 172 aAc/aGc 0 +STAG2 UCSF GRCh37 X 123200019 123200060 + splice_acceptor_variant,coding_sequence_variant,intron_variant Splice_Site DEL TTACAGTGCCCATGACCTTTCAAAGTGGGATTTATTTGCTTG TTACAGTGCCCATGACCTTTCAAAGTGGGATTTATTTGCTTG ACAGGGCCCATGCCCTTTCAAAGGGGGATTTTTTTTTTTT NOVEL P29_Pri Untested WXS Illumina HiSeq 6 0 ENST00000218089.9:c.2097-6_2132delinsACAGGGCCCATGCCCTTTCAAAGGGGGATTTTTTTTTTTT p.X699_splice ENST00000218089 NM_001042749.1 0 +TEX11 UCSF GRCh37 X 69849501 69849501 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 10 100 149 0 ENST00000395889.2:c.1613C>T p.Pro538Leu p.P538L ENST00000395889 NM_001003811.1 538 cCt/cTt 0 +THEG UCSF GRCh37 19 367122 367122 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Pri Untested WXS Illumina HiSeq 34 44 91 0 ENST00000342640.4:c.856C>T p.Pro286Ser p.P286S ENST00000342640 NM_016585.4 286 Ccc/Tcc 0 +TMCC3 UCSF GRCh37 12 94975905 94975905 + missense_variant Missense_Mutation SNP A A T NOVEL P29_Pri Untested WXS Illumina HiSeq 194 112 329 0 ENST00000261226.4:c.488T>A p.Ile163Lys p.I163K ENST00000261226 NM_020698.2 163 aTa/aAa 0 +TMEM176A UCSF GRCh37 7 150498790 150498790 + missense_variant Missense_Mutation SNP G G T NOVEL P29_Pri Untested WXS Illumina HiSeq 43 12 22 0 ENST00000484928.1:c.152G>T p.Ser51Ile p.S51I ENST00000484928 51 aGc/aTc 0 +TMTC4 UCSF GRCh37 13 101320994 101320994 + missense_variant Missense_Mutation SNP T T C NOVEL P29_Pri Untested WXS Illumina HiSeq 15 16 37 0 ENST00000342624.5:c.58A>G p.Met20Val p.M20V ENST00000342624 NM_032813.2 20 Atg/Gtg 0 +TP53 UCSF GRCh37 17 7577115 7577115 + missense_variant Missense_Mutation SNP A A G NOVEL P29_Pri Untested WXS Illumina HiSeq 6 101 153 0 ENST00000269305.4:c.823T>C p.Cys275Arg p.C275R ENST00000269305 NM_001126112.2 275 Tgt/Cgt 0 +ZNF236 UCSF GRCh37 18 74625704 74625704 + missense_variant,splice_region_variant Missense_Mutation SNP T T A NOVEL P29_Pri Untested WXS Illumina HiSeq 189 108 325 0 ENST00000253159.8:c.2905T>A p.Cys969Ser p.C969S ENST00000253159 NM_007345.3 969 Tgt/Agt 0 +ZNF394 UCSF GRCh37 7 99097486 99097486 + synonymous_variant Silent SNP T T C NOVEL P29_Pri Untested WXS Illumina HiSeq 75 58 138 0 ENST00000337673.6:c.231A>G p.Gly77= p.G77= ENST00000337673 NM_032164.2 77 ggA/ggG 0 +ADNP UCSF GRCh37 20 49508204 49508204 + frameshift_variant Frame_Shift_Del DEL T T - NOVEL P29_Rec Untested WXS Illumina HiSeq 6 0 ENST00000396029.3:c.3047delA p.Lys1016ArgfsTer11 p.K1016Rfs*11 ENST00000396029 NM_015339.2 1016 aAg/ag 0 +AHNAK2 UCSF GRCh37 14 105413143 105413143 + missense_variant Missense_Mutation SNP G G A 1000g2010nov_all_0.044 P29_Rec Untested WXS Illumina HiSeq 11 3 14 0 ENST00000333244.5:c.8645C>T p.Pro2882Leu p.P2882L ENST00000333244 NM_138420.2 2882 cCa/cTa 0 +AHNAK2 UCSF GRCh37 14 105413142 105413142 + synonymous_variant Silent SNP T T C NOVEL P29_Rec Untested WXS Illumina HiSeq 11 3 13 0 ENST00000333244.5:c.8646A>G p.Pro2882= p.P2882= ENST00000333244 NM_138420.2 2882 ccA/ccG 0 +APBA1 UCSF GRCh37 9 72067044 72067045 + frameshift_variant Frame_Shift_Del DEL AC AC - NOVEL P29_Rec Untested WXS Illumina HiSeq 15 0 ENST00000265381.4:c.1961_1962del p.Cys654Ter p.C654* ENST00000265381 NM_001163.3 654 tGT/t 0 +ATRX UCSF GRCh37 X 76813051 76813084 + frameshift_variant Frame_Shift_Del DEL AACAACTCGAAAAGACAGTGACTGCTTAGTTACT AACAACTCGAAAAGACAGTGACTGCTTAGTTACT - NOVEL P29_Rec Untested WXS Illumina HiSeq 28 0 ENST00000373344.5:c.6537_6570del p.Val2180IlefsTer11 p.V2180Ifs*11 ENST00000373344 NM_000489.3 2179 caAGTAACTAAGCAGTCACTGTCTTTTCGAGTTGTT/ca 0 +C16orf73 UCSF GRCh37 16 1884364 1884364 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 200 40 131 0 ENST00000412554.2:c.1309G>A p.Val437Ile p.V437I ENST00000412554 NM_001163560.2 437 Gtt/Att 0 +C20orf107 UCSF GRCh37 20 55108415 55108415 + synonymous_variant Silent SNP G G T NOVEL P29_Rec Untested WXS Illumina HiSeq 251 51 238 0 ENST00000371325.1:c.18G>T p.Ser6= p.S6= ENST00000371325 NM_001013646.3 6 tcG/tcT 0 +C6orf165 UCSF GRCh37 6 88144700 88144700 + frameshift_variant Frame_Shift_Del DEL A A - NOVEL P29_Rec Untested WXS Illumina HiSeq 6 0 ENST00000369562.4:c.1430delA p.Asn477IlefsTer4 p.N477Ifs*4 ENST00000369562 NM_001031743.2 475 Aaa/aa 0 +C6orf89 UCSF GRCh37 6 36867371 36867371 + frameshift_variant Frame_Shift_Del DEL C C - NOVEL P29_Rec Untested WXS Illumina HiSeq 6 0 ENST00000355190.3:c.179delC p.Pro60ArgfsTer7 p.P60Rfs*7 ENST00000355190 NM_152734.3 58 Ccc/cc 0 +CDC25B UCSF GRCh37 20 3785568 3785568 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 271 214 248 0 ENST00000245960.5:c.1703G>A p.Arg568Gln p.R568Q ENST00000245960 NM_021873.2 568 cGg/cAg 0 +COL4A4 UCSF GRCh37 2 227966580 227966580 + splice_donor_variant Splice_Site SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 121 54 138 0 ENST00000396625.3:c.975+1G>A p.X325_splice ENST00000396625 NM_000092.4 0 +DNAH5 UCSF GRCh37 5 13830849 13830849 + missense_variant Missense_Mutation SNP C C A NOVEL P29_Rec Untested WXS Illumina HiSeq 230 94 228 0 ENST00000265104.4:c.5918G>T p.Ser1973Ile p.S1973I ENST00000265104 NM_001369.2 1973 aGc/aTc 0 +DND1 UCSF GRCh37 5 140052430 140052430 + missense_variant Missense_Mutation SNP G G T 1000g2010nov_all_0.231,snp132_rs112925426 P29_Rec Untested WXS Illumina HiSeq 47 6 29 0 ENST00000542735.1:c.204C>A p.Asp68Glu p.D68E ENST00000542735 NM_194249.2 68 gaC/gaA 0 +DND1 UCSF GRCh37 5 140052424 140052424 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.301,snp132_rs72800921 P29_Rec Untested WXS Illumina HiSeq 42 6 27 1 ENST00000542735.1:c.210C>T p.Tyr70= p.Y70= ENST00000542735 NM_194249.2 70 taC/taT 0 +EFTUD2 UCSF GRCh37 17 42937310 42937310 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 38 24 46 0 ENST00000426333.2:c.1823G>A p.Arg608His p.R608H ENST00000426333 NM_001142605.1 608 cGc/cAc 0 +EPHA8 UCSF GRCh37 1 22903034 22903034 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 262 130 301 0 ENST00000166244.3:c.484C>T p.Arg162Trp p.R162W ENST00000166244 NM_020526.3 162 Cgg/Tgg 0 +FAM83H UCSF GRCh37 8 144808239 144808239 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 197 154 319 0 ENST00000388913.3:c.3392G>A p.Arg1131His p.R1131H ENST00000388913 NM_198488.3 1131 cGc/cAc 0 +GAS2 UCSF GRCh37 11 22707300 22707300 + missense_variant Missense_Mutation SNP T T C NOVEL P29_Rec Untested WXS Illumina HiSeq 97 30 75 0 ENST00000454584.2:c.232T>C p.Phe78Leu p.F78L ENST00000454584 NM_001143830.1 78 Ttc/Ctc 0 +HERC2 UCSF GRCh37 15 28419659 28419659 + synonymous_variant Silent SNP G G A 1000g2010nov_all_0.004,1000g2011may_all_0.0126,snp132_rs117437554 P29_Rec Untested WXS Illumina HiSeq 23 5 18 0 ENST00000261609.7:c.9939C>T p.Arg3313= p.R3313= ENST00000261609 NM_004667.5 3313 cgC/cgT 0 +IDH1 UCSF GRCh37 2 209113112 209113112 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 27 10 20 0 ENST00000345146.2:c.395G>A p.Arg132His p.R132H ENST00000345146 NM_005896.2 132 cGt/cAt 0 +IL1RL2 UCSF GRCh37 2 102851729 102851729 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 101 46 137 0 ENST00000264257.2:c.1670G>A p.Arg557His p.R557H ENST00000264257 NM_003854.2 557 cGc/cAc 0 +INTS1 UCSF GRCh37 7 1539622 1539622 + synonymous_variant Silent SNP G G A NOVEL P29_Rec Untested WXS Illumina HiSeq 131 68 151 0 ENST00000404767.3:c.582C>T p.Ile194= p.I194= ENST00000404767 NM_001080453.2 194 atC/atT 0 +KIAA1267 UCSF GRCh37 17 44249468 44249469 + protein_altering_variant In_Frame_Ins INS - - TGA NOVEL P29_Rec Untested WXS Illumina HiSeq 19 0 ENST00000262419.6:c.41_42insTCA p.Glu14delinsAspGln p.E14delinsDQ ENST00000262419 NM_001193466.1 14 gaa/gaTCAa 0 +KRT15 UCSF GRCh37 17 39673204 39673204 + missense_variant Missense_Mutation SNP C C A NOVEL P29_Rec Untested WXS Illumina HiSeq 57 19 67 0 ENST00000254043.3:c.594G>T p.Glu198Asp p.E198D ENST00000254043 NM_002275.3 198 gaG/gaT 0 +KRTAP5-1 UCSF GRCh37 11 1605979 1605979 + synonymous_variant Silent SNP A A G snp132_rs59646474 P29_Rec Untested WXS Illumina HiSeq 12 3 12 0 ENST00000382171.2:c.501T>C p.Cys167= p.C167= ENST00000382171 NM_001005922.1 167 tgT/tgC 0 +MEIS2 UCSF GRCh37 15 37376018 37376018 + synonymous_variant Silent SNP G G C NOVEL P29_Rec Untested WXS Illumina HiSeq 129 70 130 0 ENST00000561208.1:c.708C>G p.Ser236= p.S236= ENST00000561208 236 tcC/tcG 0 +MRVI1 UCSF GRCh37 11 10625991 10625991 + missense_variant Missense_Mutation SNP G G C NOVEL P29_Rec Untested WXS Illumina HiSeq 50 14 39 0 ENST00000423302.2:c.1704C>G p.Asn568Lys p.N568K ENST00000423302 NM_130385.3 568 aaC/aaG 0 +OBSCN UCSF GRCh37 1 228467634 228467634 + missense_variant Missense_Mutation SNP G G C NOVEL P29_Rec Untested WXS Illumina HiSeq 353 65 324 0 ENST00000570156.2:c.8796G>C p.Lys2932Asn p.K2932N ENST00000570156 NM_001271223.2 2932 aaG/aaC 0 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Missense_Mutation SNP T T C 1000g2010nov_all_0.170,snp132_rs71554688 P29_Rec Untested WXS Illumina HiSeq 24 5 11 0 ENST00000395270.1:c.2266T>C p.Tyr756His p.Y756H ENST00000395270 NM_001257190.2 756 Tac/Cac 0 +PSMD13 UCSF GRCh37 11 251848 251848 + missense_variant Missense_Mutation SNP C C T NOVEL P29_Rec Untested WXS Illumina HiSeq 118 52 122 0 ENST00000431206.2:c.953C>T p.Ser318Leu p.S318L ENST00000431206 NM_175932.2 318 tCg/tTg 0 +PTGIR UCSF GRCh37 19 47127054 47127054 + missense_variant Missense_Mutation SNP G G C NOVEL P29_Rec Untested WXS Illumina HiSeq 36 14 53 0 ENST00000291294.2:c.429C>G p.Ile143Met p.I143M ENST00000291294 NM_000960.3 143 atC/atG 0 +RBBP7 UCSF GRCh37 X 16870935 16870935 + missense_variant Missense_Mutation SNP T T G NOVEL P29_Rec Untested WXS Illumina HiSeq 24 10 36 0 ENST00000380084.4:c.954A>C p.Glu318Asp p.E318D ENST00000380084 NM_001198719.1 318 gaA/gaC 0 +RNF167 UCSF GRCh37 17 4846190 4846190 + missense_variant Missense_Mutation SNP G G A NOVEL P29_Rec 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UDhUAZwB3DboNyQ3HA1MN4wBsAHwDPACoALoAgQBjAG4N0gFUDfsNvgBtAH0MgwBiAIIAhQCXARQBFQxwDHEMeQx6DHUMdgC5D3MAwQE6DKEM8AyWDJcRPhE/DH4AeQx3DHsMjQCEAIwAgwCNAIoAjwCQAJEAjgCVAJYAAACUAJwAnQCbAPMCaQJ/AHECewJ8An0AegKAAn4CagAAsAAssAATS7AqUFiwSnZZsAAjPxiwBitYPVlLsCpQWH1ZINSwARMuGC2wASwg2rAMKy2wAixLUlhFI1khLbADLGkYILBAUFghsEBZLbAELLAGK1ghIyF6WN0bzVkbS1JYWP0b7VkbIyGwBStYsEZ2WVjdG81ZWVkYLbAFLA1cWi2wBiyxIgGIUFiwIIhcXBuwAFktsAcssSQBiFBYsECIXFwbsABZLbAILBIRIDkvLbAJLCB9sAYrWMQbzVkgsAMlSSMgsAQmSrAAUFiKZYphILAAUFg4GyEhWRuKimEgsABSWDgbISFZWRgtsAossAYrWCEQGxAhWS2wCywg0rAMKy2wDCwgL7AHK1xYICBHI0ZhaiBYIGRiOBshIVkbIVktsA0sEhEgIDkvIIogR4pGYSOKIIojSrAAUFgjsABSWLBAOBshWRsjsABQWLBAZTgbIVlZLbAOLLAGK1g91hghIRsg1opLUlggiiNJILAAVVg4GyEhWRshIVlZLbAPLCMg1iAvsAcrXFgjIFhLUxshsAFZWIqwBCZJI4ojIIpJiiNhOBshISEhWRshISEhIVktsBAsINqwEistsBEsINKwEistsBIsIC+wBytcWCAgRyNGYWqKIEcjRiNhamAgWCBkYjgbISFZGyEhWS2wEywgiiCKhyCwAyVKZCOKB7AgUFg8G8BZLbAULLMAQAFAQkIBS7gQAGMAS7gQAGMgiiCKVVggiiCKUlgjYiCwACNCG2IgsAEjQlkgsEBSWLIAIABDY0KyASABQ2NCsCBjsBllHCFZGyEhWS2wFSywAUNjI7AAQ2MjLQAAALgB/4WwAY0AS7AIUFixAQGOWbFGBitYIbAQWUuwFFJYIbCAWR2wBitcWACwBCBFsAMrRAGwBSBFsAMrRLAGIEW6AAV//wACK7EDRnYrRFmwFCsAAAAAAgwCvALZAFIAXQBdAEoANABZAFQARABBAFAAHwAbABkATgBbAFcATAAwADIAPwBpADgARgBIADoAPQAWADYALgAOAGAAKgAAAAAAAAEUAAABFAAAARQAAAEUAAABfAAAAgwAAAO4AAAFIAAABmgAAAeQAAAH6AAACDAAAAh4AAAI6AAACWQAAAnQAAAKFAAACmAAAArEAAALWAAAC8QAAAyEAAANgAAADhQAAA8gAAAP/AAAEGAAABFUAAASMAAAEpAAABKoAAAS3AAAEyQAABNcAAAUJAAAFWAAABXEAAAWjAAAF0wAABfAAAAYOAAAGKQAABmoAAAaGAAAGlQAABrMAAAbNAAAG4AAABv8AAAccAAAHQAAAB2EAAAeQAAAHygAACBUAAAgtAAAISgAACFwAAAiHAAAInwAACLYAAAjNAAAI5gAACQAAAAkbAAAJKQAACTcAAAlGAAAJsQAACd0AAAoKAAAKOQAACmgAAAqOAAAKzAAACvEAAAsJAAALJgAAC0AAAAtPAAALhAAAC6kAAAvNAAAL+wAADCoAAAxFAAAMjgAADLkAAAzgAAAM8QAADRwAAA0zAAANWgAADXEAAA2cAAANqwAADdUAAA4EAAAOCAAADg0AAA5LAAAOpQAADuEAAA8SAAAPJQAAD4gAAA+OAAAPlQAAD9sAAA/vAAAQBQAAEAkAABAQAAAQIwAAEEkAABBQAAAQfwAAEMAAABDPAAAQ/QAAESEAABEmAAARSwAAEWcAABGXAAARnAAAEecAABI8AAASqgAAEq8AABK1AAASuwAAEsEAABLHAAASzQAAEtMAABL9AAATTgAAE1QAABNaAAATYAAAE2YAABNsAAATcgAAE3gAABN+AAATrwAAE7UAABO7AAATwQAAE8cAABPNAAAT0wAAE+AAABQZAAAUHwAAFCUAABQrAAAUMQAAFDcAABRaAAAUlAAAFJoAABSgAAAUpgAAFKwAABSyAAAUuAAAFRoAABVrAAAVcQAAFXcAABV9AAAVgwAAFYkAABWPAAAVlQAAFZsAABXSAAAV2AAAFd4AABXkAAAV6gAAFfAAABX2AAAWEgAAFk0AABZTAAAWWQAAFl8AABZlAAAWawAAFpoAABagAAAWpgAAFqwAABayAAAWuAAAFucAABdpAAAXbwAAF3UAABd7AAAXgQAAF4cAABeNAAAXkwAAF5kAABefAAAXpQAAF9YAABgVAAAYGwAAGCEAABgnAAAYLQAAGDMAABg5AAAYbQAAGLoAABjAAAAYxgAAGMwAABjSAAAY2AAAGN4AABjkAAAY6gAAGPAAABj2AAAY/AAAGQIAABkzAAAZZwAAGW0AABlzAAAZeQAAGX8AABmFAAAZiwAAGa4AABnZAAAZ3wAAGfAAABn2AAAZ/AAAGgIAABoIAAAaDgAAGhQAABotAAAaMwAAGjkAABo/AAAaRQAAGksAABpRAAAaVwAAGl0AABp+AAAamQAAGp8AABqlAAAaqwAAGrEAABq3AAAavQAAGsMAABr3AAAbJAAAGyoAABswAAAbNgAAGzwAABtCAAAbSAAAG48AABvbAAAb4QAAG+cAABvtAAAb8wAAG/kAABv/AAAcBQAAHAsAABwRAAAcFwAAHIMAABztAAAc8wAAHPkAAB0zAAAdgwAAHYkAAB2PAAAdtAAAHeoAAB3wAAAd9gAAHfwAAB4CAAAeCAAAHg4AAB4UAAAeGgAAHiAAAB4mAAAeXwAAHqIAAB6oAAAergAAHrQAAB66AAAewAAAHsYAAB7MAAAe0gAAHtgAAB7eAAAe5AAAHwIAAB9AAAAfhQAAH4kAAB+7AAAf4AAAIBIAACAXAAAgVAAAII0AACCRAAAgxAAAIOwAACEfAAAhJAAAIUMAACFHAAAhiQAAIagAACHVAAAiIQAAIk0AACKLAAAipAAAIsIAACLkAAAjBAAAIyIAACNQAAAjhgAAI6gAACPMAAAj+wAAJDIAACRpAAAkowAAJOAAACUWAAAlSQAAJX4AACXNAAAmFwAAJi8AACZlAAAmlQAAJr4AACbuAAAnCwAAJzYAACdrAAAncAAAJ5gAACe9AAAn7wAAKA8AACgwAAAoYgAAKJYAACjFAAApCwAAKT4AACl7AAApogAAKaYAACmsAAAp1gAAKdoAACngAAAp5gAAKewAACnyAAAp+AAAKf4AACoEAAAqCgAAKhAAACoWAAAqHAAAKiIAACooAAAqLgAAKjQAACo6AAAqQAAAKkgAACpPAAAqVwAAKl8AACpnAAAqbwAAKncAACp/AAAqhAAAKowAACqTAAAqmwAAKqIAACqoAAAqrgAAKv8AACtMAAArUgAAK1gAACteAAArZAAAK5wAACvSAAAr2AAAK94AACvkAAAr6gAAK/AAACv2AAAr/AAALAIAACwIAAAsDgAALDoAACxAAAAsRgAALE8AACxVAAAsWwAALGEAACxnAAAsbQAALHMAACx5AAAsfwAALIUAACyLAAAskQAALJcAACydAAAsowAALKkAACyvAAAstQAALLsAACzBAAAsxwAALM0AACzTAAAs2QAALN8AACzlAAAs6wAALPEAACz3AAAs/QAALQMAAC0JAAAtDwAALRUAAC1KAAAtgAAALYYAAC2MAAAtrAAALdEAAC34AAAt/gAALgQAAC5EAAAukwAALpsAAC6iAAAuqAAALq8AAC61AAAuuwAALsMAAC7KAAAu0AAALtYAAC7rAAAvMwAAL30AAC+CAAAvtwAAL7wAAC/wAAAv9QAAMDoAADBwAAAwpgAAMNcAADDcAAAxKgAAMWwAADFwAAAxzQAAMgoAADIuAAAydwAAMr4AADL6AAAzKgAAM3QAADN5AAAzpgAAM9oAADP/AAA0GAAANDYAADR2AAA0oQAANLUAADTpAAA07gAANSYAADVjAAA1kQAANb8AADXcAAA2CwAANkoAADaGAAA2igAANo8AADarAAA2zQAANuQAADcFAAA3IAAANzwAADdmAAA3awAAN7wAADfbAAA4CAAAOCcAADhdAAA4YgAAOI4AADjJAAA4/gAAOSUAADkqAAA5LwAAOTQAADlLAAA5cgAAOa4AADndAAA6JAAAOkwAADp0AAA6eQAAOqcAADqtAAA6sQAAOu0AADs1AAA7OQAAO3AAADt1AAA7hwAAO7sAADvzAAA8KwAAPG0AADzDAAA9KAAAPYIAAD3GAAA+OQAAPoIAAD7OAAA+7wAAPvYAAD8bAAA/SwAAP38AAD+EAAA/iQAAP44AAD+TAAA/mAAAP7gAAD+9AAA/wgAAP8cAAD/LAAA/0QAAP+oAAEAFAABAHwAAQCQAAEBAAABAZwAAQI4AAEC0AABAuQAAQNAAAEDVAABA6QAAQP0AAEECAABBBgAAQQoAAEEOAABBHgAAQSMAAEEoAABBLQAAQTQAAEFCAABBRwAAQUwAAEFlAABBagAAQYoAAEGbAABBtwAAQckAAEHuAABCCgAAQiUAAEI2AABCUAAAQlYAAEJbAABCYAAAQmUAAEJqAABCbwAAQoMAAEKcAABCtQAAQs4AAELkAABC+gAAQxMAAEMYAABDHgAAQyIAAEMnAABDLAAAQzEAAEM2AABDOwAAQ0AAAENFAABDSgAAQ08AAENTAABDaAAAQ30AAEOCAABDhwAAQ6AAAEO1AABD0AAAQ9UAAEPaAABD3wAAQ+QAAEPpAABD+AAAQ/0AAEQCAABEBwAARC4AAEQzAABEOAAARD0AAERMAABEUgAARGIAAERpAABEbgAARHMAAESLAABEoQAARKYAAESrAABEsAAARMgAAETNAABE4gAARPoAAET/AABFFwAARS8AAEVOAABFUwAARWkAAEWAAABFhQAARYoAAEWPAABFqAAARa0AAEWyAABFtwAARc8AAEX7AABGAAAARgUAAEYKAABGDwAARhQAAEYZAABGHgAARiUAAEYqAABGLwAARjQAAEY7AABGQgAARkcAAEZMAABGYwAARo0AAEaqAABGxAAARskAAEbOAABG0gAARtcAAEbbAABG4AAARuUAAEbqAABG8AAARvYAAEcKAABHMQAARzoAAEdBAABHRwAAR10AAEddAABHYgAAR2cAAEduAABHcwAAR3gAAEd9AABHqQAAR64AAEezAABHzgAASCcAAEg9AABIZQAASGoAAEh3AABIfAAASKYAAEirAABIvgAASMMAAEjIAABIzQAASNIAAEjXAABI3AAASOEAAEjmAABI6wAASPAAAEj1AABI+gAASP8AAEkDAABJEgAASTEAAElZAABJXwAASWUAAElpAABJbgAASYwAAEmQAABJpAAASaoAAEmxAABJtwAASbsAAEm/AABJxQAAScsAAEnPAABJ0wAASecAAEn6AABJ/gAASgIAAEoGAABKNAAASjgAAEo8AABKTgAASlIAAEpWAABKbgAASnIAAEqHAABKiwAASqIAAEqmAABKqgAASuAAAErkAABLDwAAS0IAAEtIAABLTgAAS1QAAEtaAABLYAAAS2YAAEtsAABLpQAAS+YAAEwDAABMPQAATH0AAEyoAABM1QAATQkAAE0hAABNOQAATWQAAE2MAABNkAAATdsAAE4GAABOMQAATmAAAE6QAABOvwAATuEAAE7/AABPNgAAT18AAE+JAABPwQAAT8cAAE/NAABP0wAAT9kAAE/fAABQIgAAUE4AAFBUAABQWgAAUJAAAFDRAABRBQAAUTMAAFFvAABRkwAAUZcAAFGbAABRvgAAUcMAAFHqAABR7wAAUfUAAFH7AABSAQAAUgcAAFI3AABSPQAAUnYAAFJ6AABSfgAAUoQAAFKIAABSwAAAUu8AAFMUAABTGgAAUyAAAFMmAABTRAAAU0gAAFNwAABTdAAAU4cAAFO3AABTuwAAU90AAFQgAABUPAAAVEIAAFRbAABUgAAAVIQAAFSIAABUjAAAVKIAAFSmAABUqgAAVK4AAFTAAABVBAAAVQgAAFUoAABVRAAAVWAAAFWGAABVqgAAVdMAAFXzAABWJQAAVlwAAFaDAABWhwAAVt4AAFb2AABXCQAAVzYAAFc6AABXWgAAV5oAAFe2AABXvAAAV9QAAFf0AABYEgAAWCwAAFgwAABYRQAAWEkAAFhNAABYZQAAWGkAAFiyAABYtgAAWNUAAFjwAABZDAAAWTIAAFlXAABZgQAAWaMAAFnQAABaCAAAWjIAAFo4AABaPgAAWn8AAFqFAABasgAAWrYAAFq6AABawAAAWsQAAFr1AABbIQAAW1YAAFtcAABbYgAAW2gAAFuGAABbtQAAW+AAAFwOAABcPwAAXIIAAFzEAABc5AAAXP4AAF0qAABdUwAAXXMAAF2UAABdxQAAXfUAAF5rAABe1AAAXtgAAF7cAABfCwAAXzoAAF9OAABfYgAAX2gAAF9uAABfdQAAX3wAAF+0AABf7AAAX/QAAF/8AABgAgAAYAgAAGCCAABgoAAAYKQAAGCrAABgsgAAYM8AAGDhAABhhAAAYb8AAGH8AABiKgAAYloAAGKKAABiwgAAYtgAAGLuAABjEAAAYzIAAGNbAABjjQAAY7kAAGPkAABkNAAAZIcAAGSrAABkzQAAZPAAAGUSAABlPAAAZWUAAGWEAABlogAAZcgAAGXtAABmDgAAZi0AAGZZAABmjQAAZtsAAGcbAABnWQAAZ5YAAGe0AABn0gAAZ+kAAGf9AABoJAAAaEcAAGhmAABohAAAaKsAAGjSAABo9AAAaRQAAGlBAABpawAAaYcAAGmiAABp9gAAakUAAGqXAABq8QAAawAAAGsGAABrDAAAazoAAGtqAABrmQAAa8QAAGvoAABsDAAAbDMAAGxYAABseQAAbJkAAGy9AABs4QAAbOUAAGzrAABs8QAAbPcAAGz9AABtAQAAbQUAAG0LAABtEQAAbUQAAG1JAABtTwAAbVUAAG1bAABtYQAAbWcAAG1tAABtcQAAbXUAAG17AABtgQAAbYcAAG2NAABtkwAAbZkAAG2dAABtoQAAbacAAG2tAABtswAAbbkAAG2/AABtxQAAbcsAAG3RAABt1wAAbd0AAG3jAABt6QAAbgMAAG4dAABuIwAAbikAAG5cAABujwAAbrYAAG7aAABu/AAAbxwAAG9fAABvoQAAb80AAG/1AABv+QAAb/0AAHABAABwBQAAcCIAAHBAAABwYQAAcIEAAHCnAABwzgAAcPIAAHEcAABxTgAAcXkAAHGlAABx7AAAcgYAAHItAAByaAAAco8AAHK4AAByzQAAcvgAAHM3AABzYgAAc34AAHPEAABz5wAAdAkAAHQwAAB0dgAAdJ8AAHTcAAB1AQAAdUEAAHVrAAB1ugAAdeYAAHYIAAB2NQAAdpoAAHa+AAB3CgAAdyEAAHddAAB3kQAAd7gAAHf/AAB4AwAAeBoAAHgpAAB4RQAAeEkAAHh6AAB4jgAAeMQAAHjxAAB5LgAAeWIAAHmNAAB5wAAAeeEAAHoLAAB6SwAAenoAAHqhAAB6tAAAeucAAHskAAB7SAAAe20AAHuwAAB72AAAfAUAAHxGAAB8YAAAfI4AAHy+AAB85AAAfRsAAH1UAAB9mwAAfckAAH3tAAB+FwAAflAAAH50AAB+uwAAfs8AAH8NAAB/TAAAf3sAAH/IAAB/7gAAgAQAAIAcAACAVwAAgF0AAIBpAACAbwAAgHcAAICIAACAjgAAgJUAAICkAACAvAAAgM8AAIDUAACA3AAAgOEAAIDwAACA/gAAgQ8AAIEdAACBLgAAgTMAAIE3AACBPAAAgU0AAIFmAACBagAAgYsAAIGqAACB2wAAgfMAAIIRAACCHgAAgjYAAIJPAACCeQAAgogAAIKaAACCswAAgtwAAIL3AACDIAAAgywAAINFAACDZgAAg5kAAIO3AACD5gAAhAAAAIQXAACEPAAAhFAAAIR5AACEmgAAhK0AAITAAACE1gAAhOwAAIUQAACFTQAAhWQAAIV7AACFmwAAhb4AAIXiAACGAwAAhicAAIZHAACGZwAAhrMAAIbMAACG1gAAhyUAAIclAACHQwAAh2AAAId2AACHpgAAh9cAAIf6AACIFQAAiEQAAIhmAACIegAAiJwAAIi0AACIyQAAiNoAAIlVAACJbwAAiX4AAImZAACJpwAAifYAAIpEAACKZAAAioQAAIrAAACK7gAAixIAAIs4AACLXwAAi4cAAIuhAACL5wAAjBUAAIxRAACMiwAAjJwAAIy2AACMzQAAjPIAAI0GAACNGgAAjS8AAI1GAACNYgAAjX4AAI2UAACNsgAAjdAAAI3oAACN9wAAjg8AAI4lAACORQAAjmcAAI6eAACO0QAAjuAAAI7uAACPFwAAj2AAAI9zAACPngAAj80AAI/SAACP2AAAj+YAAI/tAACP8wAAkFIAAJC3AACRGAAAkZAAAJHWAACSNQAAkooAAJLyAACS+AAAkv4AAJMxAACTbQAAk3MAAJN5AACT5QAAlFYAAJSoAACVCQAAlTYAAJV/AACV1QAAlhMAAJZrAACWrgAAlyEAAJdfAACXkQAAl88AAJgeAACYaQAAmJoAAJjOAACZHQAAmWIAAJm2AACZ3wAAmeUAAJoSAACaWwAAmpwAAJrjAACbGAAAm1AAAJuEAACbigAAm8kAAJwdAACcIwAAnF0AAJypAACc2wAAnSMAAJ16AACdiQAAnY8AAJ2dAACd0AAAnekAAJ4aAACeVQAAnoEAAJ6GAACeqAAAnuIAAJ8AAACfJgAAnzQAAJ9CAACfSAAAn04AAJ9rAACfjAAAn5wAAJ+yAACfuAAAoEUAAKBVAACgYgAAoH0AAKCYAACgvgAAoM4AAKDUAACg2gAAoOAAAKDmAACg7AAAoPIAAKD4AACg/gAAoQQAAKFyAACh+QAAokkAAKKyAACiwQAAoscAAKLtAACjFwAAo0MAAKOCAACjwgAAo/gAAKRCAACkegAApJsAAKTSAACk+QAApQsAAKURAAClFwAApR0AAKUjAAClKQAApS8AAKU5AACldQAApaYAAKXyAACmEwAAphkAAKZiAACmkQAAprwAAKb8AACnRgAAp6cAAKgHAACoaQAAqN4AAKlSAACpqQAAqhIAAKpcAACqwgAAqwUAAKthAACrpgAAq/EAAKw5AACseAAArNsAAK0PAACtZgAArdEAAK4NAACuigAAruQAAK8wAACvbwAAr6QAAK/cAACwTwAAsJsAALDNAACxCQAAsTsAALF1AACxtAAAsd0AALIkAACyWwAAsocAALKNAACy0gAAsyMAALNPAACzhwAAs7UAALPKAAC0AgAAtCMAALRRAAC0lQAAtMgAALTrAAC0+QAAtQcAALUuAAC1dwAAtX4AALWFAAC1kwAAtdMAALYKAAC2EAAAthYAALYcAAC2eAAAtyQAALdvAAC3dQAAt50AALfRAAC39wAAuCkAALhqAAC4vQAAuP0AALk6AAC5eQAAuccAALn3AAC6KgAAuj0AALpzAAC6iAAAurUAALsAAAC7EwAAu1YAALuEAAC7tgAAu9IAALwAAAC8FQAAvFwAALylAAC89wAAvVQAAL2yAAC9uAAAvb4AAL3EAAC9ygAAviEAAL4nAAC+cgAAvrEAAL7pAAC/OQAAv4UAAL/EAADAIQAAwFUAAMDAAADBEAAAwUAAAMF/AADB0QAAwiEAAMJnAADCpwAAwwcAAMNHAADDgAAAw8cAAMP9AADERwAAxIAAAMTWAADFDgAAxU4AAMV/AADFwgAAxhkAAMZiAADGrAAAxuMAAMcZAADHLwAAx0kAAMd3AADHowAAx7kAAMfeAADH9gAAyB8AAMhFAADIeQAAyIwAAMifAADI8QAAyTcAAMl6AADJwwAAyh4AAMpEAADKhgAAyrkAAMsKAADLYQAAy5IAAMv0AADMJgAAzFoAAMypAADM0wAAzPIAAM00AADNjQAAzkMAAM56AADOoQAAzuQAAM9vAADQFgAA0IIAANCIAADQ2AAA0N4AANFWAADRugAA0iAAANKaAADSoAAA0vcAANL9AADTAwAA01sAANOoAADT4AAA1DcAANShAADU1wAA1UIAANW7AADWKwAA1qMAANbaAADXAAAA10kAANeuAADYDwAA2F8AANiJAADYygAA2PwAANk1AADZiAAA2cIAANoHAADaaQAA2rwAANrpAADbOwAA23cAANueAADbzAAA3DAAANyEAADcuQAA3QMAAN1jAADdqgAA3f0AAN4cAADeXAAA3ogAAN6qAADe2QAA3w4AAN9TAADflAAA4AkAAOBIAADgkQAA4JcAAOCdAADgowAA4KkAAODGAADg3gAA4SUAAOHSAADiUAAA4rMAAOMpAADjUwAA44QAAOO2AADj+wAA5DYAAOSLAADk4AAA5SQAAOVmAADltgAA5fMAAOY3AADmqgAA5tUAAOc/AADnugAA6A4AAOiYAADo/QAA6U8AAOnNAADqKwAA6qYAAOraAADrFwAA614AAOuzAADr6wAA7CwAAOyTAADs0gAA7PoAAO00AADtlQAA7c8AAO4OAADuQQAA7oMAAO7PAADvGgAA70UAAO+vAADwBwAA8G0AAPCiAADw9AAA8S4AAPF4AADxtwAA8fYAAPIgAADyawAA8rUAAPLjAADzUAAA87wAAPPtAAD0KgAA9HAAAPTEAAD0+AAA9T8AAPWRAAD1zwAA9fEAAPYvAAD2kAAA9tAAAPcPAAD3QwAA94MAAPfJAAD4DQAA+EIAAPigAAD49gAA+VUAAPmMAAD52AAA+g4AAPpWAAD6kwAA+tgAAPsDAAD7TQAA+5UAAPu9AAD8JAAA/JEAAP0DAAD9OAAA/W4AAP3HAAD+DgAA/hMAAP4YAAD+HQAA/joAAP6JAAD+oQAA/vsAAP86AAD/UQAA/5YAAP/RAAD//wABACMAAQA8AAEAWgABAHgAAQC7AAEA7AABAV4AAQF1AAEBiQABAeYAAQIRAAECUwABAngAAQK6AAEC2QABAwcAAQNjAAEDmgABA7YAAQPuAAEEGgABBEkAAQR7AAEEvAABBQMAAQUeAAEFNQABBWgAAQWsAAEFyQABBhUAAQZpAAEGsAABBwUAAQdQAAEHdAABB8IAAQfnAAEIBwABCD8AAQijAAEI0gABCPEAAQkPAAEJWAABCYgAAQmkAAEJxAABCdYAAQoLAAEKWQABCrMAAQrXAAEK6gABCxoAAQtZAAELsgABC9MAAQwNAAEMLgABDF8AAQx5AAEMoAABDNAAAQ0QAAENbAABDbgAAQ3/AAEOLgABDlwAAQ6xAAEO/gABDz4AAQ9qAAEPrwABD+EAAQ/lAAEP+AABD/4AARARAAEQFwABECsAARAxAAEQOQABED8AARBFAAEQWQABEF8AARBlAAEQawABEHEAARB3AAEQfQABEIMAARCJAAEQjwABEJcAARCfAAEQpwABEK0AARCzAAEQuwABEMMAARDLAAEQ/AABEQIAAREVAAERJQABETQAARFQAAERbQABEYkAARGuAAERtAABEboAARHPAAER4AABEf8AARIZAAESHwABEiUAARIrAAESMQABEkQAARJKAAESXAABEmIAARJyAAESeAABEoAAARKGAAESjAABEpwAARKiAAESqAABEq4AARK0AAESugABEsAAARLGAAESzAABEtIAARLaAAES4gABEugAARLuAAES9AABEvoAARMCAAETFAABEyUAARNJAAETZgABE2wAAROIAAETjgABE6gAAROuAAETtgABE7wAARPCAAET3AABE+IAARPoAAET7gABE/QAARP6AAEUAgABFAgAARQOAAEUFAABFBoAARQgAAEUJgABFCwAARQ0AAEUPAABFEQAARRfAAEUZQABFGsAARRxAAEUdwABFJ0AARSjAAEUyQABFM8AART1AAEU+wABFQMAARUpAAEVLwABFTUAARU7AAEVQQABFUcAARVNAAEVUwABFVkAARVfAAEVZQABFWsAARVxAAEVdwABFX0AARWDAAEViwABFbIAARXZAAEV3wABFeUAARXrAAEV8QABFhEAARYXAAEWNwABFj0AARZdAAEWYwABFmsAARaLAAEWkQABFpcAARadAAEWowABFqkAARaxAAEWuQABFr8AARbFAAEWzQABFtUAARbbAAEW4QABFukAARbxAAEW+QABFxgAARc3AAEXSwABF1EAARdlAAEXawABF38AAReFAAEXjQABF6AAARemAAEXrAABF7IAARe4AAEXvgABF8QAARfMAAEX0gABF9gAARfgAAEX6AABF+4AARf0AAEX/AABGAQAARgMAAEYIAABGDwAARhQAAEYfgABGKkAARjNAAEY0wABGPcAARj9AAEZIQABGScAARkvAAEZUwABGVkAARlfAAEZZQABGWsAARlxAAEZdwABGX0AARmFAAEZqwABGcgAARnuAAEaCwABGhEAARouAAEaNAABGlEAARpXAAEaXwABGnwAARqCAAEaiAABGo4AARqUAAEamgABGqAAARqmAAEarAABGrIAARq4AAEavgABGsQAARrKAAEa0gABGtoAARr3AAEbDwABGyEAARs7AAEbQQABG1oAARtgAAEbegABG4AAARuIAAEbogABG6gAARuuAAEbtAABG7oAARvAAAEbyAABG9AAARvWAAEb3AABG+QAARvsAAEb8gABG/gAARv+AAEcBAABHAwAARwkAAEcagABHIIAARyWAAEcxgABHPkAAR0tAAEdMwABHTkAAR0/AAEdRQABHXQAAR2jAAEdqQABHe4AAR30AAEeOQABHj8AAR5FAAEeSwABHlEAAR5XAAEeXwABHmcAAR5tAAEecwABHnkAAR5/AAEehQABHosAAR6RAAEelwABHt4AAR7zAAEe+QABHw4AAR8UAAEfKQABHy8AAR83AAEfSwABH1EAAR9XAAEfXQABH2MAAR9pAAEfcQABH3kAAR9/AAEfhQABH4sAAR+RAAEflwABH50AAR+jAAEfqQABH7EAAR/EAAEf4QABIAAAASANAAEgLwABIFEAASBzAAEgeQABIJsAASChAAEgwgABIMgAASDpAAEhCwABIREAASEzAAEhOwABIUMAASFnAAEhfgABIZAAASG+AAEhxAABIfEAASH3AAEiJQABIisAASJaAAEiYAABImgAASJwAAEilgABIswAASMCAAEjNwABI2wAASNyAAEjeAABI64AASO0AAEj6gABI/AAASP4AAEkAAABJDkAASQ/AAEkRQABJEsAASRRAAEkfwABJLIAASTlAAElFwABJUkAASV0AAElnwABJaUAASXQAAEl1gABJgEAASYHAAEmMwABJlEAASZVAAEmWwABJmEAASZpAAEmbwABJncAASZ9AAEmhQABJosAASa1AAEm3gABJwgAAScyAAEnXgABJ4sAASe4AAEn5AABJ+wAASfyAAEn+gABKAAAASgIAAEoDgABKBYAAShUAAEorgABKOoAASkmAAEpYwABKZ8AASnOAAEp/AABKisAASpaAAEqiwABKqwAASqyAAEq0wABKtkAASr6AAErAAABKx0AAStAAAErZAABK2oAASuNAAErkwABK7UAASu7AAEr3AABLAYAASwjAAEsPwABLFwAASx5AAEslAABLK4AASzIAAEs4wABLQ0AAS02AAEtYAABLYoAAS2gAAEttQABLcoAAS3fAAEuCAABLjEAAS5aAAEugwABLpsAAS6zAAEuxgABLswAAS7SAAEu5QABLv0AAS8UAAEvJwABLy0AAS8zAAEvRgABL2AAAS96AAEvjgABL7EAAS/hAAEv9QABMBoAATA/AAEwXgABMI0AATDPAAEw7gABMQwAATEqAAExSAABMU4AATFUAAExcgABMZUAATG4AAEx1gABMdwAATHiAAEyAAABMiQAATJIAAEyaQABMm8AATJ1AAEylwABMq8AATLeAAEzDQABMzoAATN3AAEzxQABM/IAATQjAAE0VAABNIYAATTIAAE1FAABNUYAATV+AAE1tgABNeoAATYuAAE2gQABNrQAATbBAAE2xQABNskAATbNAAE20QABNtcAATbbAAE3CgABNzkAATdlAAE3oAABN6YAATfSAAE4DQABOEcAATiAAAE4vAABOP8AATk5AAE5dAABOa8AATnqAAE6JAABOmcAATqoAAE65gABOyAAATteAAE7nAABO9MAATwTAAE8TgABPIUAATyvAAE82gABPQMAAT0JAAE9DwABPToAAT1uAAE9ogABPdcAAT3dAAE94wABPhgAAT5JAAE+egABPqsAAT6xAAE+twABPucAAT8jAAE/XwABP5oAAT+gAAE/pgABP+IAAUAgAAFAXQABQJsAAUDjAAFBNQABQXMAAUGhAAFBzwABQfsAAUIBAAFCBwABQjMAAUJMAAFCeQABQn8AAUKFAAFCiwABQpEAAUKXAAFCnQABQt8AAUMhAAFDXwABQ6sAAUOxAAFD7gABRD4AAUSOAAFE3AABRTkAAUWeAAFF6wABRj4AAUaVAAFG7AABR0AAAUehAAFIDQABSGEAAUipAAFI8gABSTgAAUmPAAFJ8wABSjoAAUp8AAFKvgABSwAAAUtRAAFLqwABS+0AAUwRAAFMLwABTDUAAUw7AAFMQQABTEcAAUxNAAFMUwABTFkAAUxfAAFMZQABTGsAAUxxAAFMdwABTH8AAUyFAAFMjQABTKMAAUzOAAFNBQABTT0AAU2EAAFNzgABTgIAAU43AAFOfgABTrgAAU8BAAFPWwABT48AAU/TAAFQFwABUFUAAVCOAAFQxwABURoAAVFtAAFRzgABUggAAVJBAAFSgQABUrsAAVLzAAFTOgABU38AAVO1AAFT7QABVDAAAVR1AAFUpwABVNgAAVUYAAFVSwABVYwAAVW/AAFVzQABVekAAVYPAAFWLgABVkQAAVZqAAFWhQABVssAAVbqAAFXCQABVy4AAVdEAAFXdgABV6YAAVfWAAFYHAABWGEAAViYAAFYywABWP0AAVk4AAFZcQABWbwAAVoHAAFaRAABWn8AAVq4AAFa8QABWzEAAVt7AAFbwwABW98AAVv4AAFcLAABXDAAAVw0AAFcOQABXDkAAVw9AAFcQQABXEUAAVxJAAFcTQABXFIAAVxWAAFcWgABXF4AAVxiAAFcZgABXGoAAVxvAAFcdAABXHgAAVx8AAFcgAABXIQAAVyIAAFcjQABXJIAAVyXAAFcnAABXKEAAVymAAFcqwABXLAAAVy1AAFcugABXL8AAVzEAAFcyQABXM4AAVzTAAFc2AABXN0AAVziAAFc5wABXOwAAVzxAAFc9gABXPwAAV0CAAFdCAABXQ4AAV0UAAFdGgABXSAAAV0mAAFdLAABXTIAAV04AAFdPgABXUQAAV1KAAFdUAABXVYAAV2YAAFd6AABXe4AAV30AAFd/AABXgMAAV4LAAFeEwABXhkAAV4fAAFeJQABXisAAV4xAAFeNwABXj0AAV5DAAFeSQABXk8AAV5VAAFeWwABXmEAAV5nAAFebQABXnMAAV6xAAFe+AABXv4AAV8EAAFfCgABXxAAAV8YAAFfHwABXyUAAV8rAAFfMQABXzcAAV89AAFfQwABX0kAAV9PAAFfVQABX1sAAV9hAAFfZwABX20AAV9zAAFfeQABX38AAV+FAAFfiwABX5EAAV+XAAFfnQABX6MAAV+pAAFfrwABX7UAAV+7AAFfwQABX8cAAV/PAAFf1wABX98AAV/nAAFf7wABX/YAAV/+AAFgBgABYAwAAWASAAFgGAABYB4AAWAkAAFgKgABYDAAAWA2AAFgPAABYEIAAWBIAAFgTgABYFQAAWBaAAFgYAABYGYAAWBuAAFgdAABYHwAAWCCAAFgiAABYI4AAWCUAAFgmgABYKAAAWCmAAFgrAABYLIAAWC4AAFgvgABYMQAAWDKAAFg0AABYNYAAWDcAAFg4gABYOoAAWDyAAFg+gABYQEAAWEHAAFhDQABYRMAAWEZAAFhHwABYSUAAWErAAFhMQABYTcAAWE9AAFhQwABYUkAAWFPAAFhVQABYVsAAWFhAAFhZwABYW0AAWFzAAFheQABYX8AAWGFAAFhiwABYZEAAWGXAAFhnQABYaMAAWGpAAFhrwABYbUAAWG7AAFhwQABYe0AAWIZAAFiVgABYloAAWJgAAFiZgABYmwAAWJyAAFiegABYoAAAWKIAAFijgABYpYAAWKcAAFipAABYqoAAWKwAAFitgABYr4AAWLEAAFizAABYtIAAWLaAAFi4AABYugAAWLuAAFi9AABYvoAAWMAAAFjBgABYwwAAWMSAAFjGAABYx4AAWMmAAFjLAABYzQAAWM6AAFjQgABY0gAAWNQAAFjVgABY1wAAWNiAAFjaAABY24AAWN0AAFjegABY4AAAWOGAAFjjAABY5IAAWOaAAFjoAABY6gAAWOuAAFjtgABY7wAAWPEAAFjygABY9AAAWPWAAFj3AABY+IAAWPoAAFj7gABY/QAAWP6AAFkAAABZAYAAWQMAAFkEgABZBgAAWQeAAFkJAABZCoAAWQwAAFkNgABZDwAAWRCAAFkSAABZE4AAWRUAAFkWgABZGAAAWRmAAFkbAABZHIAAWR4AAFkfgABZIQAAWSKAAFkkAABZJYAAWScAAFkogABZKgAAWSuAAFktAABZLoAAWTAAAFkxgABZMwAAWTSAAFk2AABZN4AAWTkAAFk6gABZPAAAWT2AAFk/AABZQIAAWUIAAFlDgABZRQAAWUaAAFlIAABZSYAAWUsAAFlMgABZTgAAWU+AAFlRAABZUoAAWVQAAFlVgABZVwAAWViAAFlaAABZW4AAWV0AAFlegABZYAAAWWGAAFljAABZZIAAWWYAAFlngABZaQAAWWqAAFlsAABZbYAAWW8AAFlwgABZcgAAWXOAAFl1AABZdoAAWXgAAFl5gABZewAAWXyAAFl+AABZf4AAWYEAAFmCgABZhAAAWYWAAFmHAABZiIAAWYoAAFmLgABZjQAAWY6AAFmQAABZkYAAWZMAAFmUgABZlgAAWZeAAFmZAABZmoAAWZwAAFmdgABZnwAAWaCAAFmiAABZo4AAWaUAAFmmgABZqAAAWamAAFmrAABZrIAAWa4AAFmvgABZsQAAWbKAAFm0AABZtYAAWbcAAFm4gABZugAAWbuAAFm9AABZvoAAWcAAAFnBgABZwwAAWcSAAFnGAABZx4AAWckAAFnKgABZzAAAWc2AAFnPAABZ0IAAWdIAAFnTgABZ1QAAWdaAAFnYAABZ2YAAWdsAAFncgABZ3gAAWd+AAFnhAABZ4oAAWeQAAFnlgABZ5wAAWeiAAFnqAABZ64AAWe0AAFnugABZ8AAAWfGAAFnzAABZ9IAAWfYAAFn3gABZ+QAAWfqAAFn8AABZ/YAAWf8AAFoAgABaAgAAWgOAAFoFAABaBoAAWggAAFoJgABaCwAAWgyAAFoOAABaD4AAWhEAAFoSgABaFAAAWhWAAFoXAABaGIAAWhoAAFobgABaHQAAWh6AAFogAABaIYAAWiMAAFokgABaJgAAWieAAFopAABaKoAAWiuAAFozwABaNQAAWjYAAFo3gABaOQAAWjqAAFo8AABaPYAAWj8AAFpAgABaQgAAWkOAAFpFAABaRoAAWkgAAFpJgABaSwAAWkyAAFpOAABaT4AAWlEAAFpSgABaVAAAWlWAAFpXAABaWIAAWloAAFpbgABaXQAAWl6AAFpgAABaYYAAWmMAAFpkgABaZgAAWmeAAFppAABaaoAAWmwAAFptgABabwAAWnDAAFpyQABaecAAWnrAAFp7wABafUAAWn7AAFqAQABagcAAWoNAAFqEwABahkAAWofAAFqJQABaisAAWovAAFqNAABajQAAWo0AAFqNAABajQAAWo0AAFqNAABajQAAWo0AAFqNAABajQAAWo0AAFqNAABajQAAWo0AAFqNAABajQAAWpFAAFqSQABak0AAWpbAAFqaQABam0AAWpxAAFqdgABao0AAWqmAAFqvgABatMAAWrZAAFq3wABauUAAWrrAAFrCQABazEAAWtHAAFrVgABa1oAAWtgAAFraAABa2wAAWtsAAFrbAABa2wAAWtsAAFrbAABa2wAAWtsAAFrbAABa9cAAWxdAAFsbgABbIMAAWyeAAFsrwABbMQAAWzfAAFs7gABbQIAAW0HAAFtXQABbWMAAW2VAAFtowABbbQAAW3FAAFtzwABbdgAAW3pAAFt9gABbiAAAW5KAAFuUAABblYAAW5cAAFudAABbpcAAW67AAFu4QABbuYAAW8HAAFvJgABbywAAW81AAFvaQABb3oAAW/dAAFv5QABb+8AAW/5AAFwBgABcA0AAXAXAAFwIwABcCwAAXA2AAFwNgABcDYAAXA2AAFwNgABcDYAAXA2AAFwVwABcFwAAXCBAAFwvQABcPQAAXEMAAFxTAABcYgAAXGpAAFxugABccAAAXHQAAFx1QABcdoAAXHfAAFx5AABcekAAXHuAAFx8wABcfgAAXH9AAFyAgABcgcAAXIMAAFyEQABchYAAXIbAAFyIAABciUAAXIqAAFyLwABcjQAAXI5AAFyPgABcoIAAXMWAAFzXgABc40AAXPxAAF0NQABdIMAAXUHAAF1DQABdcIAAXX0AAF2PQABdn0AAXaiAAF2xgABdswAAXcSAAF3XQABd7EAAXfdAAF4QAABeIUAAXikAAF45AABePIAAXkBAAF5DwABeR4AAXk3AAF5UAABeWUAAXlqAAF5jgABeb8AAXnGAAF5zwABedYAAXnbAAF58wABegAAAXovAAF6UwABemIAAXpqAAF6bwABeoQAAXqNAAF6pQABerkAAXrFAAF6ygABes8AAXrVAAF62wABevgAAXuSAAF8UgABfIoAAXyQAAF81wABfTsAAX25AAF9vQABfgEAAX4HAAF+tgABfy8AAX9fAAF/pAABf/8AAYBvAAGAxQABgVAAAYG6AAGCAQABgiUAAYIvAAGCNgABgocAAYKyAAGC9gABg7EAAYQoAAGEbwABhLAAAYT+AAGFBQABhQ4AAYUVAAGFMQABhU4AAYVSAAGFVwABhd4AAYXjAAGF5wABhesAAYajAAGHSAABh0wAAYd6AAGIDQABiLoAAYi/AAGJNgABiToAAYk+AAGJQgABiUYAAYleAAGJZQABiW4AAYmfAAGJvAABieQAAYnpAAGJ7gABigEAAYoGAAGKPgABinQAAYp5AAGK9gABivsAAYsDAAGLCwABixEAAYsZAAGLIQABiykAAYsvAAGLNwABiz0AAYtFAAGLTQABi1UAAYtbAAGLXwABi2UAAYttAAGLcwABi3cAAYt9AAGLhQABi48AAYuVAAGLmQABi58AAYunAAGLqwABi68AAYuzAAGLtwABi7sAAYvBAAGLyQABi88AAYvTAAGL2QABi+EAAYvrAAGL8QABi/UAAYv7AAGMAwABjAcAAYwLAAGMDwABjBMAAYwqAAGMQAABjFYAAYxtAAGMlAABjLoAAYzYAAGM3wABjOQAAYzrAAGNCwABjTEAAY02AAGNOwABjWMAAY2LAAGNogABjboAAY3KAAGN2wABjeIAAY3pAAGN7gABjfMAAY36AAGOAQABjggAAY4PAAGOFgABjjsAAY5fAAGOZAABjmkAAY5vAAGOdQABjpIAAY6uAAGOygABjugAAY8OAAGPMwABjzgAAY94AAGPkQABj7wAAY/zAAGQEAABkEUAAZCCAAGQlQABkKgAAZDQAAGRPAABkVsAAZFgAAGRzQABkdIAAZHXAAGR8AABkfUAAZIRAAGSHwABkiQAAZIqAAGSLwABkj0AAZJUAAGSegABkn4AAZKJAAGSkAABkpcAAZLOAAGTCAABkx0AAZMsAAGTUwABk3kAAZOIAAGTnAABk6IAAZPGAAGTywABk9gAAZPdAAGT+gABlBoAAZQgAAGUKAABlG4AAZTmAAGU7wABlPQAAZT7AAGVAQABlQcAAZUPAAGVGwABlSMAAZUnAAGVWAABlaAAAZWnAAGV2wABleAAAZXmAAGWKAABli4AAZZ+AAGWzQABltMAAZcvAAGXNQABlz0AAZdDAAGXiAABl44AAZeWAAGXngABl6YAAZevAAGXtwABl70AAZfEAAGXywABl9IAAZfYAAGX3gABl+oAAZfxAAGX+AABmBcAAZgfAAGYRwABmFEAAZhYAAGYXwABmGYAAZhtAAGYcwABmHgAAZjCAAGY2AABmO4AAZkPAAGZMAABmTcAAZk+AAGZRQABmUwAAZllAAGZagABmXEAAZl4AAGZfgABmYQAAZmsAAGZ1QABmfMAAZn4AAGaSwABmp4AAZqkAAGaqgABmuYAAZsfAAGbSwABm1EAAZtXAAGbbwABm3QAAZt7AAGbggABm4kAAZuOAAGblAABm5oAAZvPAAGb+wABnAEAAZwIAAGcDgABnBUAAZwbAAGcNAABnDkAAZxUAAGcbwABnIgAAZynAAGcxgABnNYAAZzmAAGc7QABnPQAAZz7AAGdAQABnQcAAZ0WAAGdGwABnSAAAZ1BAAGdVwABnWoAAZ2FAAGdiwABnZIAAZ2ZAAGdnwABnaQAAZ2sAAGdsQABneAAAZ4PAAGeRQABnnsAAZ6BAAGehwABno0AAZ6TAAGenAABnqQAAZ6tAAGetgABnvQAAZ8IAAGfHQABnyIAAZ8nAAGfPQABn1IAAZ9XAAGfaAABn20AAZ98AAGfjQABn58AAZ+tAAGfvwABn8QAAZ/JAAGfzgABn+IAAZ/wAAGgBgABoAsAAaAQAAGgFQABoC8AAaBGAAGgXwABoG0AAaCGAAGgnQABoLYAAaDCAAGg1AABoOUAAaDvAAGg+QABoQMAAaENAAGhFwABoSEAAaErAAGhNQABoT0AAaFFAAGhTQABoVUAAaFdAAGhZQABoW0AAaF1AAGhfwABoYkAAaGTAAGhnQABoacAAaGxAAGhuwABocUAAaHPAAGh1wABoeEAAaHrAAGh8wABofsAAaIDAAGiCwABohMAAaIdAAGiWwABoncAAaJ/AAGilQABosgAAaMKAAGjXwABo80AAaQZAAGkcwABpNQAAaUVAAGlfwABpeEAAaZDAAGmUAABpl4AAaZlAAGmbAABposAAaasAAGmswABproAAabcAAGnAwABpwoAAacRAAGnJgABpzwAAadSAAGnaAABp28AAad2AAGnfQABp4QAAaeLAAGnkgABp5kAAaegAAGnpQABp6oAAaevAAGntAABp84AAafpAAGoCgABqCsAAahFAAGoZQABqIUAAaigAAGopQABqKoAAaivAAGotAABqLkAAai+AAGowwABqMgAAajPAAGo1gABqN0AAajkAAGo6wABqPIAAaj5AAGpAAABqQcAAakOAAGpFQABqRwAAakjAAGpKgABqTEAAak4AAGpWQABqX0AAamCAAGppAABqasAAamyAAGpuQABqeIAAanpAAGp8AABqfUAAaoaAAGqHwABqiYAAaotAAGqTwABqmAAAapnAAGqggABqp8AAarAAAGqxwABqs4AAarVAAGq3AABquMAAarqAAGq7wABqvQAAar5AAGrGAABqzoAAatjAAGraAABq20AAatyAAGreQABq4AAAauHAAGrjgABq5UAAaucAAGryAABq/YAAawtAAGsOwABrEkAAaxXAAGsZQABrHMAAayBAAGsjwABrKEAAayzAAGsxQABrNMAAazhAAGs7wABrP0AAa0LAAGtGQABrR4AAa45AAGwoAABscQAAbHJAAGxzgABseAAAbHlAAGx6gABsgAAAbIZAAGyIAABsiUAAbIqAAGyMQABsjgAAbJJAAGyYwABsooAAbKQAAGyvQABssQAAbMzAAGzawABs3IAAbPxAAGz9gABtA0AAbQdAAG0NgABtD0AAbREAAG0UwABtGcAAbRzAAG0hwABtIwAAbScAAG0owABtKoAAbSxAAG0uAABtL8AAbTlAAG06gABtO8AAbT0AAG0+QABtQAAAbUQAAG1FwABtR4AAbUlAAG1KgABtTgAAbVNAAG1ZgABtZ0AAbWvAAG11QABtm4AAba/AAG3BQABtxoAAbdAAAG3RQABt0wAAbdTAAG3egABt58AAbeyAAG3twABt9QAAbgLAAG4LgABuDMAAbhHAAG4TgABuFMAAbhaAAG4eQABuH4AAbiKAAG4kQABuJYAAbidAAG4wgABuNwAAbjhAAG4+QABuP4AAbkgAAG5QAABuVQAAblnAAG5kgABuboAAbnBAAG5xgABuc0AAboEAAG6CwABuhAAAboXAAG6KQABujAAAbo3AAG6UAABumMAAbp8AAG6kAABupUAAbtGAAG7jQABu+MAAbw1AAG8XAABvJ8AAby7AAG9CgABvVwAAb13AAG9iAABvhkAAb44AAG+YQABvpkAAb7WAAG/CQABvyEAAb9QAAHB3QABweMAAcIoAAHCZgABwmwAAcKoAAHCugABwtwAAcMIAAHDRgABw18AAcNzAAHDjAABw7MAAcPBAAHDzwABw+sAAcQGAAHERwABxHEAAcSLAAHEtAABxMsAAcT5AAHFMwABxWQAAcV0AAHFkwABxasAAcXaAAHF9gABxh4AAcYxAAHGSwABxnoAAcayAAHGygABxuEAAcbwAAHHGgABxzoAAcdwAAHHqwABx88AAcgBAAHIIQAByEkAAciFAAHIuwAByO0AAck7AAHJWQAByWwAAcnRAAHJ/wAByhAAAcooAAHKNAABynQAAcqDAAHK0wAByuEAAcrzAAHLCwAByxMAAcskAAHLKQAByy8AAcs1AAHLOwABy0EAActHAAHLTQABy1gAActfAAHLZgABy3IAAculAAHLqQABzAcAAcx8AAHM2AABzR4AAc2CAAHN7wABznsAAc6wAAHO+wABzysAAc9oAAHPgQABz7gAAc/6AAHQNQAB0HMAAdDqAAHRfAAB0bwAAdIZAAHSPQAB0nUAAdKUAAHSugAB0uIAAdMdAAHTaAAB09IAAdQTAAHUUAAB1NgAAdUvAAHVWwAB1aUAAdYJAAHWiwAB1tUAAdc4AAHXjAAB1+MAAdhbAAHY4wAB2PYAAdlhAAHZsAAB2hYAAdpzAAHawQAB2wsAAdtfAAHbywAB3EMAAdzMAAHdAgAB3VEAAd1nAAHdngAB3cUAAd4wAAHeiAAB3vYAAd8wAAHfewAB37QAAd/hAAHgLwAB4HgAAeCuAAHg9wAB4WIAAeGSAAHh4gAB4hUAAeJ8AAHiwwAB4yUAAeNkAAHjugAB5A8AAeRjAAHkqAAB5QMAAeU6AAHlhwAB5ZsAAeXOAAHl/gAB5jIAAeZvAAHmwQAB5vcAAec9AAHnkgAB5/AAAegXAAHoZAAB6JkAAejxAAHpTgAB6csAAeosAAHqygAB6xIAAesxAAHraAAB68YAAevuAAHsRgAB7J0AAe0AAAHtVQAB7XQAAe2xAAHt6QAB7jUAAe53AAHurwAB7vwAAe9mAAHv6gAB8DsAAfBfAAHwdQAB8KcAAfDHAAHxDAAB8V0AAfGlAAHx9AAB8kUAAfKlAAHy9QAB82IAAfOgAAH0CAAB9DUAAfR4AAH0tQAB9SQAAfVcAAH1gQAB9a4AAfXTAAH2JgAB9oMAAfarAAH26wAB92AAAfeoAAH4CQAB+IAAAfjLAAH5MQAB+XIAAfnJAAH6BAAB+m4AAfrCAAH7MgAB+4kAAfv3AAH8agAB/MoAAf04AAH9jQAB/esAAf4VAAH+WQAB/oEAAf7NAAH/DAAB/z0AAf9oAAH/rgAB/+EAAgAvAAIAeAACAKoAAgDnAAIBMAACAWcAAgHQAAICGQACAksAAgJ2AAICrQACAxcAAgNaAAIDrgACBCUAAgRSAAIEvgACBUAAAgWeAAIGGAACBjkAAgZ6AAIG1QACB0cAAgdoAAIHoAACB+8AAghNAAIIbgACCLoAAgjxAAIJWQACCZQAAgnzAAIKSgACCr0AAgsPAAILfAACC9oAAgxTAAIMqgACDPUAAg1UAAINtAACDhYAAg6QAAIO3AACDxEAAg+NAAIQGgACEHMAAhDVAAIRCgACEX4AAhITAAIScgACEuEAAhL0AAITKAACE04AAhOZAAIT1wACFC8AAhSPAAIUsQACFPAAAhUxAAIVegACFdYAAhZaAAIW1AACF2sAAheMAAIX0AACGA0AAhg0AAIYgAACGOQAAhlcAAIZ5AACGioAAhqcAAIbAwACG1MAAhuTAAIb5gACHEYAAhySAAIc3wACHQYAAh06AAIdlwACHeMAAh31AAIeAwACHh4AAh6EAAIfCQACH10AAh+FAAIftQACIAwAAiBhAAIgnAACIMEAAiEnAAIhXwACId0AAiIfAAIiPAACIoEAAiLPAAIjKgACI3gAAiOIAAIj9wACJD8AAiRxAAIkogACJOQAAiUyAAIlhQACJeEAAiY6AAImewACJoAAAiaEAAImiQACJpcAAianAAIm1wACJxIAAidEAAIncQACJ7cAAif5AAIoPQACKKkAAikLAAIpZgACKb8AAiokAAIqKgACKkgAAipOAAIqdQACKpYAAiquAAIqzQACKucAAisPAAIrKgACK0IAAitjAAIrfQACK4MAAiuJAAIrkQACK5kAAiufAAIrpQACK6sAAiuxAAIrtwACK70AAivDAAIryQACK88AAivVAAIr2wACK+EAAivnAAIr7QACK/MAAiv5AAIr/wACLAUAAiwLAAIsEQACLBcAAiwdAAIsIwACLCkAAiwvAAIsNQACLDsAAixBAAIsWwACLFsAAixbAAIsWwACLGUAAiyNAAIsqgACLOkAAi0AAAItKAACLXsAAi2hAAIt2wACLf4AAi41AAIuawACLrIAAi7jAAIvCwACLzMAAi9fAAIvfQACL6MAAi/OAAIv9AACMAoAAjAnAAIwRgACMGEAAjCPAAIw2QACMPUAAjELAAIxQAACMX0AAjHQAAIx6AACMiQAAjJsAAIyrwACMt4AAjMBAAIzPgACM4MAAjO2AAIz+wACNDoAAjR9AAI0zwACNQcAAjU8AAI1ggACNdkAAjYQAAI2awACNp4AAjbIAAI28gACNyIAAjdqAAI3rAACN/cAAjgpAAI4fAACOMoAAjkGAAI5KgACOWgAAjmvAAI59QACOh0AAjpZAAI6iwACOtkAAjtYAAI74wACPCoAAjxnAAI8rQACPNoAAj0ZAAI9JgACPTwAAj1fAAI9dQACPZoAAj3IAAI98QACPp8AAj76AAI/EwACP18AAj+2AAI/2wACP/0AAkAzAAJAaAACQLAAAkEnAAJBegACQeQAAkJ1AAJCxQACQv8AAkM7AAJDkQACQ/wAAkQ9AAJEfQACRLEAAkTXAAJFBgACRVgAAkWeAAJF4gACRicAAkapAAJGrQACRrEAAkbvAAJHPwACR0MAAkeFAAJH8AACSBAAAkgwAAJIcQACSJIAAkjTAAJI8AACSQ4AAkkoAAJJVAACSXcAAkmgAAJJ3QACShQAAko3AAJKaQACSooAAkq0AAJLAgACSyoAAktHAAJLdwACS7oAAkvcAAJMCgACTCsAAkxeAAJMhgACTNkAAkz2AAJNCgACTScAAk0+AAJNYQACTZ0AAk2rAAJN4AACThAAAk5EAAJObwACTr0AAk7uAAJPFgACTzEAAk9mAAJPlQACT88AAlAbAAJQZAACUKEAAlDiAAJRMAACUWIAAlGSAAJR7gACUjwAAlJ2AAJS7AACU1EAAlOeAAJT2gACVA0AAlQvAAJUegACVK4AAlTcAAJVBgACVTsAAlV9AAJVpgACVe4AAlYwAAJWWAACVmYAAlahAAJW6wACVyQAAldhAAJXlAACV+IAAlgjAAJYXwACWG0AAlicAAJY4gACWSAAAllHAAJZegACWbUAAlniAAJaSAACWrQAAlsiAAJbkAACW/EAAlxOAAJczQACXU8AAl3SAAJeUgACXsEAAl8fAAJfZgACX+cAAmBRAAJgnwACYPsAAmFPAAJhugACYhcAAmJ0AAJixAACYx4AAmOVAAJj8gACZD4AAmSyAAJlAQACZWAAAmXVAAJmMQACZoQAAmbXAAJnbQACZ9IAAmhaAAJpBQACaW4AAmnzAAJqZwACavkAAmuMAAJsGgACbMQAAm0pAAJtmQACbgcAAm55AAJvAQACb5oAAm/9AAJwaAACcMQAAnE8AAJxwAACcjcAAnKdAAJzCwACc2oAAnPlAAJ0fgACdTEAAnYCAAJ2jwACdxUAAnePAAJ4JwACeJ8AAnknAAJ5fwACefYAAnp2AAJ7EAACe7AAAnwmAAJ8yQACfX0AAn3wAAJ+WAACfs4AAn9hAAJ/+wACgJMAAoEFAAKBmgACghoAAoKdAAKDAwACg2gAAoPlAAKEjwAChPEAAoVRAAKFqAAChi4AAoavAAKG/wACh1UAAoe6AAKIBgACiIIAAojXAAKJNQACiaMAAoojAAKKlgACiwAAAotnAAKLrQACjAQAAoxjAAKMswACjRAAAo1OAAKNsQACjiIAAo65AAKPDQACj2AAAo/DAAKQMgACkNAAApFBAAKRnQACkioAApJ1AAKS4gACk1gAApPPAAKUZgAClM4AApUYAAKVagAClc8AApYlAAKWhgAClwEAApdKAAKXpgACmBYAAphtAAKY6QACmUgAApmbAAKZ/AACmlQAApq9AAKbGgACm54AApwMAAKchwACnMYAAp0eAAKdYgACnawAAp4KAAKeXwACntoAAp9IAAKfygACoCoAAqCPAAKg4gACoVMAAqHnAAKiiAACovIAAqN/AAKj+AACpHwAAqUhAAKlkgACpfgAAqZsAAKmxQACpzYAAqfLAAKoMQACqKUAAqkyAAKp7QACqk8AAqrcAAKrVQACq6sAAqwMAAKsfgACrPAAAq1/AAKt9AACrlcAAq7dAAKvZAACr+UAArBTAAKw1AACsVMAArGxAAKyQAACsr4AArMmAAKzjAACtB8AArS1AAK1GwACtX8AArXoAAK2dAACtuYAArd8AAK35QACuDoAAribAAK5LgACubUAArojAAK6nwACuxwAArvFAAK8bQACvM0AAr1FAAK9vwACvlIAAr62AAK/EgACv2gAAr/XAALAaAACwQUAAsFqAALB9QACwmAAAsLEAALDNAACw54AAsP0AALEPAACxKoAAsUWAALFewACxhUAAsZjAALGtgACxwAAAsdJAALHsgACyCcAAsiPAALI3wACySQAAslsAALJvwACyfkAAspLAALKjQACytgAAssVAALLWAACy5wAAsvzAALMSQACzL4AAsz7AALNXQACzbAAAs4MAALOWAACzp0AAs7oAALPJwACz8cAAtBNAALQsAAC0UwAAtHVAALSfQAC0xIAAtO6AALUVAAC1M0AAtUpAALVwQAC1kEAAtaYAALXGgAC14YAAtgWAALYjgAC2P0AAtlbAALZogAC2hoAAtq2AALbOQAC28kAAtxCAALc3AAC3V8AAt3eAALeSQAC3soAAt87AALfvwAC4C4AAuC7AALhNQAC4f4AAuKvAALjFQAC42MAAuQaAALkjQAC5TUAAuXIAALmdgAC5xMAAufSAALoewAC6PEAAulXAALpnQAC6h8AAuquAALrMwAC6/cAAuykAALtcwAC7jgAAu7LAALvSAAC74sAAu/eAALwPAAC8H0AAvDfAALxIwAC8acAAvIXAALyZAAC8rUAAvMDAALzRwAC868AAvQJAAL0ZAAC9NkAAvUeAAL1oAAC9f0AAvZPAAL2lwAC9tAAAvcMAAL3ZwAC97kAAvfuAAL4LwAC+GgAAvirAAL48wAC+SUAAvlvAAL5qgAC+dwAAvoeAAL6bgAC+sYAAvr2AAL7MgAC+2YAAvvAAAL8CwAC/E4AAvyBAAL8ugAC/R4AAv1pAAL9nQAC/eEAAv4sAAL+awAC/o8AAv6lAAL+vAAC/wQAAv8oAAL/XQAC/68AAv/lAAMATQADAOsAAwEaAAMBbAADAbUAAwIZAAMChAADAsoAAwMoAAMDgAADA9EAAwQRAAMEagADBJkAAwTXAAME/wADBToAAwVAAAMFRgADBUwAAwVSAAMFWAADBV4AAwVkAAMFagADBXIAAwX2AAMGagADBrwAAwbyAAMHHAADB3UAAwe7AAMIIgADCHgAAwjEAAMJDgADCWkAAwnIAAMKPAADCpUAAwrnAAMLMQADC4cAAwusAAML6gADDBsAAwxrAAMMowADDQsAAw1BAAMNfAADDd0AAw4xAAMOmwADDsMAAw7lAAMPHgADD2oAAw+2AAMP0QADD/AAAxAUAAMQUQADEIAAAxC+AAMQ6AADERgAAxFQAAMRqAADEeIAAxImAAMSbgADEpgAAxLiAAMTCQADEz8AAxN+AAMTqAADE/QAAxROAAMUkgADFNoAAxUpAAMVqgADFkUAAxbYAAMXQwADF8UAAxgtAAMYpAADGPsAAxl/AAMZ3AADGkcAAxqYAAMa8AADG0kAAxuSAAMb8wADHFMAAxy1AAMdNgADHbgAAx4fAAMehgADHwcAAx90AAMfzgADIDMAAyBVAAMgkQADINwAAyEWAAMhTgADIZkAAyHnAAMh7QADIfMAAyIqAAMiXwADIpQAAyLzAAMjQAADI2YAAyOBAAMjyAADI/cAAyRFAAMkqQADJLcAAyS9AAMlEgADJSsAAyU7AAMlfQADJccAAyXNAAMl0wADJdkAAyXfAAMl5QADJesAAyZMAAMmhwADJo0AAyaTAAMmmQADJp8AAyalAAMmqwADJwMAAydsAAMn3gADKBMAAyhXAAMoqgADKPsAAykuAAMpcAADKc0AAyoSAAMqYwADKrEAAysFAAMrPQADKz0AAyt7AAMrogADLAIAAyxuAAMszQADLP4AAy1VAAMtrwADLdcAAy3dAAMt4wADLekAAy3vAAMt9QADLf0AAy4FAAMuCwADLhEAAy4ZAAMuhAADLuMAAy9XAAMvvwADMAUAAzBEAAMwZAADMJ8AAzDHAAMw+gADMTQAAzFdAAMxkAADMb4AAzHeAAMx8wADMiEAAzJYAAMyhQADMqQAAzLXAAMzDQADMyMAAzOwAAMz4AADNGwAAzUGAAM1eQADNX8AAzWFAAM1iwADNZEAAzWXAAM1nQADNaMAAzWpAAM1rwADNbUAAzW7AAM1wQADNccAAzXNAAM10wADNdkAAzXfAAM15QADNesAAzXxAAM19wADNf0AAzYDAAM2CQADNg8AAzZ3AAM26wADN2AAAzdoAAM3cAADN3gAAzeAAAM3hgADN44AAzf5AAM4NAADOH4AAzihAAM4xgADOQEAAzkSAAM5KQADOVUAAzl6AAM5iwADOZsAAzm0AAM5zQADOdoAAzoAAAM6GAADOkkAAzp4AAM6lgADOrcAAzrTAAM7EgADOy8AAztAAAM7XwADO3gAAzuNAAM7uAADO9YAAzv9AAM8IAADPFEAAzyHAAM80gADPOsAAz0KAAM9GwADPUYAAz1dAAM9dAADPYwAAz24AAM99gADPjYAAz5cAAM+jgADPq4AAz7cAAM/GQADP4sAA0AKAANAdwADQPMAA0GuAANCJgADQrsAA0NaAAND7QADRHsAA0UwAANF+gADRocAA0c0AANH9gADSI8AA0lIAANKFAADSsIAA0uWAANMeQADTRUAA027AANOcQADTx0AA0/kAANQjwADUWIAA1JAAANSygADU3QAA1Q1AANUugADVWMAA1YZAANWjAADVyMAA1fLAANYZAADWR4AA1nmAANafQADWzwAA1wIAANcygADXbkAA17CAANf4AADYKEAA2GGAANifQADY1kAA2P0AANksAADZXwAA2Y4AANmygADZ4AAA2hHAANouAADaUUAA2m8AANqEAADancAA2rOAANrMAADa6UAA2wrAANsyAADbVQAA23EAANuWAADbv8AA2+ZAANv5gADcFIAA3DXAANxQQADccMAA3JgAANzEAADc7QAA3RVAAN1EwADdekAA3YyAAN2jwADdwYAA3dTAAN3yQADeFEAA3idAAN5CgADeZAAA3oGAAN6nAADe0QAA3vDAAN8XQADfOEAA31xAAN99gADfp4AA39cAAN/1QADgHIAA4EpAAOBswADglgAA4LIAAODTAADg+YAA4RwAAOFFgADhdoAA4a1AAOHDgADh4QAA4fLAAOIMgADiLYAA4lUAAOKFAADiu4AA4uxAAOMZgADjUUAA442AAOOxQADj3MAA5ANAAOQpAADkWAAA5I1AAOS1AADk4sAA5QzAAOU7AADlbwAA5bAAAOX2gADmNkAA5mwAAOapQADm7kAA5xUAAOdEwADnekAA558AAOfKAADn8AAA6BtAAOhAQADobUAA6KBAAOjGwADo9EAA6RcAAOlEQADpdkAA6aNAAOnSwADqDQAA6k5AAOqJAADqtwAA6vCAAOsxwADrX0AA65SAAOvRwADr5wAA7ALAAOwVwADsKwAA7D4AAOxYgADsd4AA7IgAAOygwADsvQAA7M9AAOznAADtAIAA7SAAAO08wADtYEAA7YqAAO25AADt4wAA7hMAAO5HQADuZUAA7opAAO6zQADu18AA7vDAAO8RAADvNkAA71kAAO+AAADvogAA78HAAO/qgADwGEAA8DXAAPBZgADwfoAA8KsAAPDawADxBsAA8ToAAPFxQADxk8AA8bTAAPHdAADyCsAA8jWAAPJgQADykYAA8ssAAPLzQADzJAAA81iAAPOJgADzuEAA8++AAPQpgAD0RcAA9GvAAPSVwAD0r4AA9M3AAPTrAAD1C4AA9S5AAPVVQAD1gkAA9a2AAPXcAAD2BIAA9jcAAPZtQAD2ikAA9q/AAPbZQAD2/UAA9xZAAPc6QAD3YcAA948AAPe2gAD304AA9/nAAPglAAD4TQAA+GZAAPiIQAD4r8AA+NVAAPkDAAD5MoAA+U6AAPlxwAD5mQAA+b5AAPnnQAD6C4AA+jgAAPpqQAD6lcAA+r5AAPrswAD7IYAA+0gAAPt3AAD7qcAA+9hAAPv9gAD8IkAA/FRAAPxoAAD8f0AA/JaAAPy1gAD82QAA/O1AAP0JwAD9KQAA/UTAAP1cgAD9eIAA/ZDAAP2sgAD9wAAA/duAAP38QAD+FgAA/jSAAP5RQAD+dQAA/p4AAP7DQAD+7UAA/xeAAP9JQAD/f4AA/6eAAP/YQAEAC8ABADpAAQBbgAEAjIABALtAAQDOQAEA6YABAQeAAQEdAAEBN8ABAU1AAQFmwAEBgUABAaGAAQHHgAEB3wABAf6AAQIjQAECQwABAlYAAQJxgAECkIABAqWAAQLBwAEC10ABAvGAAQMKQAEDJ4ABA0mAAQNpwAEDjsABA60AAQPTwAEEAIABBBdAAQQ2QAEEWMABBHXAAQSYAAEErUABBMoAAQTqQAEFBkABBR2AAQU8wAEFYEABBXjAAQWYAAEFvMABBdrAAQYBwAEGLcABBkBAAQZZgAEGecABBpNAAQarQAEGy4ABBvAAAQcCgAEHHgABBz7AAQdawAEHc0ABB5TAAQe9QAEHz8ABB+sAAQgLQAEILYABCFbAAQiEgAEInAABCLeAAQjQgAEI7wABCQmAAQksgAEJU8ABCXXAAQmbwAEJx0ABCe6AAQoagAEKNcABCleAAQp/QAEKmgABCryAAQrkAAELB4ABCyeAAQtQQAELfUABC5GAAQuuAAELz4ABC++AAQwXgAEMQoABDGJAAQyJgAEMtQABDNvAAQ0AAAENK0ABDVxAAQ12AAENlIABDbyAAQ3pgAEOGUABDjgAAQ5dwAEOiEABDq5AAQ7ZgAEPCMABDzTAAQ9UwAEPeoABD6TAAQ/DgAEP60ABEBaAARAxwAEQVYABEH1AARCXQAEQuAABEN8AARECAAERLYABEVvAARF/gAERq8ABEdtAARIFAAESJMABEk5AARJ7gAESnQABEsTAARLoAAETEAABEzzAARNvQAETnYABE9LAARQNAAEUUMABFJBAARS4QAEU50ABFRqAARVIwAEVb8ABFZ1AARXQAAEV/sABFjEAARZWgAEWg0ABFrZAARbSwAEW98ABFyIAARdOAAEXbgABF5bAARfGwAEX8YABGCLAARhXgAEYcYABGI9AARinwAEYxQABGN2AARj8wAEZIIABGTYAARlPQAEZZkABGYCAARmYgAEZt8ABGdwAARnugAEaCYABGipAARpFAAEaXQABGn6AARqmAAEauMABGtRAARr0QAEbD8ABGyFAARs8QAEbWcABG3fAARuagAEbxAABG+GAARwDwAEcIMABHEsAARx6gAEcrMABHNvAAR0NAAEdQ8ABHXxAAR2dwAEdyAABHfeAAR4fAAEeS8ABHnxAAR6qwAEe38ABHxlAAR9YgAEflIABH7aAAR/ggAEgDwABIDDAASBbwAEgicABILRAASDTAAEg+sABIScAASFNwAEhaUABIY2AASG1gAEhz0ABIe4AASIIQAEiHMABIjcAASJMwAEibgABIpWAASK+QAEi44ABIwqAASM5AAEjZ4ABI4DAASOfAAEjwsABI+OAASP7AAEkGwABJEBAASRfAAEkgsABJKtAASTQwAEk/QABJSzAASVhAAEleQABJZmAASW+QAEl3IABJgKAASYrQAEmR0ABJmwAASaUgAEmtUABJuCAAScQAAEnJkABJ0UAASdnwAEnhEABJ6jAASfQgAEn5wABKAMAASgZQAEoLQABKEoAAShtgAEojQABKLVAASjfgAEo8QABKQpAASkpAAEpRgABKWiAASmIAAEpowABKcgAASnwgAEqF0ABKkFAASp1AAEqrsABKuUAASsHgAErMYABK2EAASuBAAErqEABK9MAASv4QAEsFsABLD5AASxogAEsjUABLLoAASzqQAEtEEABLT4AAS1xAAEtoQABLc1AAS4CAAEuOgABLlyAAS6CQAEupIABLtPAAS8IgAEvP8ABL3NAAS+owAEv5AABMCEAATBbgAEwi8ABMMWAATECwAExJ4ABMVMAATGDgAExqwABMdfAATIAwAEyMQABMmTAATKHgAEysoABMt9AATMQQAEzSEABM4OAATOowAEz1YABNAZAATQ0AAE0XsABNJEAATTHwAE08kABNSQAATVbAAE1foABNaoAATXagAE1+kABNiLAATZQAAE2aUABNoZAATaggAE2v0ABNuYAATcTAAE3QkABN23AATeaAAE3zQABOALAATgzwAE4XcABOJAAATjHwAE468ABORlAATlJgAE5Z8ABOY2AATm3gAE52kABOgRAATozAAE6WEABOoGAATqxAAE62wABOwoAATszAAE7ZAABO5fAATuyAAE708ABO/qAATweAAE8PQABPGMAATyNgAE8rEABPNPAATz+wAE9JcABPUqAAT13AAE9pgABPchAAT3zQAE+IYABPj2AAT5iwAE+jEABPrEAAT7JQAE+6YABPw4AAT8vwAE/WEABP4TAAT+ngAE/0cABQAAAAUApQAFAUYABQIGAAUC2wAFA14ABQP/AAUErwAFBUsABQYFAAUGzwAFBzsABQe4AAUIJwAFCJMABQkXAAUJuAAFChIABQqSAAULHwAFC5kABQwAAAUMiQAFDSUABQ26AAUObgAFDzUABQ+8AAUQUQAFEQkABRHmAAUSygAFEzsABRPCAAUUZwAFFSQABRXnAAUWoAAFF3oABRhXAAUY2QAFGXgABRovAAUa0QAFG4YABRxMAAUdGgAFHgIABR76AAUfewAFICEABSDUAAUhagAFIhgABSLbAAUjXQAFI/0ABSS2AAUlMwAFJdMABSaEAAUnCwAFJ7cABShwAAUpCAAFKcAABSqJAAUqzgAFKy8ABStvAAUr0gAFLEIABSyOAAUtCAAFLXwABS3oAAUuQgAFLr8ABS9UAAUvqAAFMC4ABTDJAAUxYAAFMfEABTJLAAUykwAFMwEABTOPAAU0EwAFNIcABTTQAAU1LAAFNYcABTXjAAU2OAAFNpgABTcfAAU3igAFN9cABThCAAU4mgAFOOMABTkwAAU5uwAFOikABTp8AAU64wAFO2UABTvRAAU8RAAFPF4ABTyYAAU87QAFPVkABT1uAAU9dAAFPXoABT2TAAU9uAAFPfcABT4GAAU+FQAFPigABT4tAAU+PgAFPk8ABT5eAAU+ZAAFPmoABT5wAAU+dAAFPngABT58AAU+gAAFPoQABT6IAAU+jAAFPpAABT6UAAU+mAAFPp4ABT6kAAU+7AAFPvIABT8UAAU/ZAAFP2oABT9wAAU/eAAFP34ABT+EAAU/igAFP5AABT+WAAU/nAAFP9YABUAWAAVAGwAFQB8ABUBlAAEACP/dQL9AyAAGwAfACMAJwCZALInAwArtCEEADcEK7AgL7QkBAA3BCuwHi+0HwQAHQQrsBIvsRkE6bISGQors0ASFgkrAbAoL7Ag1rQkBQA8BCuwJBCxFgErsRUF6bAVELEeASuwCDKxHQXpsAYysB0QsQ8BK7EABemwABCxJQErtCMFADwEK7EpASuxHR4RErIMEhk5OTmwDxGwBDkAsRIfERKxAAc5OTAxARQOAx0BIzU0PgM1NCYjIgYVIzQ2MzIWAxUjNQURIRElIREhAmslNDUlWiU1NCVGOkk4VW9sYXSzWv7FAtr9eQI0/cwCCC5KMS05IC83JUIwMD0jMz9SSnN3aP3raGjWA6v8VUYDHwACAHwAAADQAtkABQAJADwAsggAACu0CQQAHQQrsgUDACsBsAovsATWsAgytAEFADwEK7AGMrQBBQA8BCuxCwErALEFCRESsAI5MDETEQcjJxETFSM10BYnFlNUAtn+rt/fAVL9j2hoAAIAKAHQASUCxQAFAAsAXgCyAAIAK7AGM7QEBAAJBCuwCTIBsAwvsAXWsQIF6bMDAgUIK7QEBQARBCuwBC+0AwUAEQQrsAIQsQsBK7EIBemzCQgLCCu0CgUAEQQrsAovtAkFABEEK7ENASsAMDETMxUHIyc3MxUHIycoXRsnG6BdGycbAsVvhoZvb4aGAAAAAAIADv/sAh4CuQAbAB8BSQCyDgAAK7IJCg0zMzOwEC+zCAsMDyQXM7QRBAArBCuzBRIeHyQXMrAUL7MEExwdJBcztBUEACsEK7MBFhkaJBcyshUUCiuzQBUXCSuyABgbMjIyAbAgL7EhASuwNhq6Pv30qAAVKwqwDi6wGC6wDhCxDQf5sBgQsRcH+bo+8vRwABUrCrAKLrAALrAKELEJB/mwABCxGwf5sAkQswEJABMrswQJABMrswUJABMrswgJABMrsAoQswsKGxMrsA0QswwNGBMrsA4Qsw8OFxMrsxIOFxMrsxMOFxMrsxYOFxMrsA0QsxkNGBMrsAoQsxoKGxMrsxwKGxMrsA0Qsx0NGBMrsx4NGBMrsAoQsx8KGxMrA0AYAAEEBQgJCgsMDQ4PEhMWFxgZGhscHR4fLi4uLi4uLi4uLi4uLi4uLi4uLi4uLi4usEAaADAxAQczFSMHMxUjByM3IwcjNyM1MzcjNTM3MwczNwMjBzMB5SRdah9pdSdMJnwnTCZlch9seSRMJH0jMHwgfQK5xESuRNPT09NErkTExMT++K4AAAAAAwAh/4ICBgMCACsAMQA4AMUAsgYAACuwAzO0EgQAKwQrsDIysgYSCiuzQAYFCSuwEy+xLATpsC0vsCMztBkEADcEK7AcMrIZLQors0AZGgkrAbA5L7AW1rQwBQAxBCuwCCDWEbQJBQAmBCuwMBCxBQErshIZLDIyMrQEBQARBCuyGyMyMjIysAQQsTUBK7QABQA8BCuwICDWEbQfBQAmBCuxOgErsTAJERKwCzmwBRGwDTkAsRMSERKyAAg4OTk5sCwRsCQ5sC0SsRYfOTmwGRGwHTkwMSUUBgcVIzUmNTMeBxcRLgE1NDY3NTMVHgEVIy4BJxUeBiU1DgEVFBM+ATU0JicCBm9pO9JPAgEGBw0SGiQWaF1lYDtbZ08BQDIENBwzHyIQ/u04PK9DQzlNw2BzB2dnDtkUDSUPHg8SCwMBEB9PWFVnDDY2B2lVN0YC+QEOChYbJzix8Ag+MVr+eghKNzE2FwAABQAd/+wDWwLFAAkAFQAZACQAMACxALIgAAArsBgztCsEADcEK7IWAgArtCUaIBYNK7QlBAA3BCu0EAYgFg0rtBAEADcEK7EAFhAgwC+0CgQANwQrAbAxL7AI1rQNBQAbBCuwDRCxEwErtAMFABsEK7ADELEjASu0KAUAGwQrsCgQsS4BK7QdBQAbBCuxMgErsRMNERK0BQYAGBkkFzmxLigRErMWGiAXJBc5ALElKxESsiIjHTk5ObEKEBESsgcIAzk5OTAxEzIWFRQGIiY0NhciBhUUFjMyNjU0JiUzASMBMhYVFAYjIiY0NhciBhUUFjMyNjU0JsdIY2SMZWRGKTw8Kik8OwFvQv51QgHaSGNlRUdkZEYpPDwqKTw7Aq1kSUVkZYxlRjsqKTw7KSs7Xv0nAVZkSEVkZYxkRjspKjs7KCs7AAAAAAMANP/pAn0CxQAeACoAMwCOALIeAAArsgQAACuxMgTpshACACu0JQQANwQrAbA0L7AH1rEvBemzDS8HCCu0KAUAPAQrsC8QsSIBK7QSBQAmBCuwEhCxGAErtBoFADEEK7E1ASuxKC8RErAKObAiEbQQDxUsMiQXObASErIAFis5OTmxGhgRErEcHjk5ALElMhEStgcNEgAcHywkFzkwMSUGBwYjIiY1NDY3LgE1NDYyFhUUBgcXNj0BMxQHFyMDPgE1NCYjIgYVFBYTJw4BFRQWMzIB0jIgO0RccUVdLyJkjlw8ToUfUDp6bfM7LDEmJy8ZsqBENk02SU4xEiJtWkRbNjtFI0JbWEU2TCyjNzwEXlmXAa8lNCIlMC8nGyv+psgrRSo1SwAAAQA1AdAAkwLFAAUAOgCyAAIAK7QEBAAJBCsBsAYvsAXWsQIF6bECBemzAwIFCCu0BAUAEQQrsAQvtAMFABEEK7EHASsAMDETMxUHIyc1XhsoGwLFb4aGAAEASf8sASMC2QAKABsAsgADACsBsAsvsAnWtAMFADEEK7EMASsAMDETMwYVFBcjJgI0Nuw3iYk3S1hYAtnd+fjfYgD/7P4AAAEAJv8sAQAC2QAKABsAsgUDACsBsAsvsAPWtAkFADEEK7EMASsAMDEXIzY1NCczHgEUBl03iYk3S1hY1N35+N9i/+z+AAAAAAEAKAG5AVcC2QAOADUAsgADACu0CQQABwQrsAcyAbAPL7AO1rQCBQARBCuxEAErsQIOERKwCDkAsQAJERKwCDkwMRMzBzcXBxcHJwcnNyc3F6A/BWoTbEYzPj8yRWwTagLZcCY7HlkkXV0kWR47JgABADL/9gIWAdoACwBSALIEAAArsAYvsAEztAcEADcEK7AAMrIHBgors0AHCQkrAbAML7AE1rAIMrQDBQAbBCuwCjKyAwQKK7NAAwEJK7IEAwors0AEBgkrsQ0BKwAwMQEVIxUjNSM1MzUzFQIWz0bPz0YBC0bPz0bPzwAAAQBX/20AwABoAAoAQwCyCgAAK7QABAAdBCuwBC+0BQQAEwQrAbALL7AE1rAAMrQCBQAwBCu0AgUAMAQrsAIQtAgFABEEK7AIL7EMASsAMDE3MxUUIzU+AT0BI1dpaR0YNWh4gyYCJjMSAAAAAQAuAPABHwE4AAMAKACwAi+0AwQANwQrtAMEADcEKwGwBC+xAgErtAEFAAkEK7EFASsAMDEBFSM1AR/xAThISAAAAAABAFAAAAC4AGgAAwA1ALICAAArtAMEAB0EK7ICAAArtAMEAB0EKwGwBC+wAta0AQUAOgQrtAEFADoEK7EFASsAMDE3FSM1uGhoaGgAAf/4/+wBHALZAAMASQCyAwAAK7ACM7IAAwArsAEzAbAEL7AD1rQBBQAHBCuxBQErsDYauj0F7LEAFSsKsAMQsQII+bABELEACPkDsQACLi6wQBoAMDETMwMj5TftNwLZ/RMAAAIAK//pAfsCxQANABUARwCyCwAAK7QSBABDBCuyBgIAK7EPBOkBsBYvsADWsRAF6bAQELEVASuxCAXpsRcBK7EVEBESsQsGOTkAsQ8SERKxCAA5OTAxEzQ+AzMyERQGIyImACAREDMyNjUrHi5AOyHod3FydgF2/uSMSkYBV1mITTAQ/oyvubsB0/7f/tyQlwAAAAABAGYAAAFbAsUACABDALIIAAArsgUCACu0AgEIBQ0rtAIEAB8EKwGwCS+wCNaxBwXpsggHCiuzQAgBCSuwBxC0BQUAEQQrsAUvsQoBKwAwMQEjNT4BNzMRIwEDnWY+FzpYAfk/DS5S/TsAAAABACIAAAH/AsUAGQBsALIOAAArsQsE6bICAgArsRcE6bIXAgors0AXAAkrAbAaL7AA1rEZBemwGRCxFAErsQwF6bAFMrIUDAors0AUDgkrsRsBK7EZABESsAs5sBQRswcJEQIkFzmwDBKwDTkAsRcLERKxBRE5OTAxEzYzMhYVFA8BDgEHIRUhPgE/ATY1NCYjIgcyB+NlfpZkQTgHAXX+KAZSb1xgUDyFCgHP9nRchFI2I0ItV3V/PzQ3VTlMqQABACD/6QH6AsUAJACOALIRAAArsRcE6bIXEQors0AXEwkrsgYCACuxAATpsgAGCiuzQAAECSu0Hx4RBg0rsR8E6QGwJS+wBNaxAwXpsBMg1hGxFAXpsAMQsRoBK7EOBemwIiDWEbEJBemxJgErsQMUERKwFTmwIhG1BgsRFxweJBc5ALEeFxESsQ4aOTmwHxGwCzmwABKwCTkwMQEiBgcjNjMyFhUUBx4BFRQGIyInMx4BMzI2NTQjByM1PgE1NCYBDkw5AlgF2WVzY0A4g23aEFgFSEhFTpMlC19PQwJ4U0XlaFtsJxZPRGV45U1KS0OBAUsCLEE4QQAAAAACABwAAAIIAsUACgANAFwAsgoAACuyAwIAK7QBDQoDDSuwBTOxAQTpsAcyAbAOL7AK1rALMrEJBemwBDKyCQoKK7NACQcJK7IKCQors0AKAQkrsQ8BK7EJChESsAM5ALEDDRESsQIMOTkwMSUhNQEzETMVIxUjNREDAUf+1QFCQWlpWN6qXQG+/jRPqvkBNv7KAAAAAQAj/+kCAQLFACEApwCyCwAAK7EWBOmyFgsKK7NAFhMJK7IhAgArsQIE6bQFHAshDSuxBQTpshwFCiuzQBwfCSuwIDIBsCIvsBLWtBQFADwEK7AUELEZASuxCAXpsSMBK7A2Gro/X/cKABUrCrAgLrACLg6wIBCxAwT5BbACELEhBPkDALADLgGzAgMgIS4uLi6wQBqxGRQRErIFCx85OTmwCBGxAQA5OQCxHBYRErAIOTAxARUhBzYzMhYVFAYjIi4FJzMWMzI2NTQmIyIGByMTAdz+2Rw7SGZ/iGspRS0lExEEA1gfckhTVEcpOh9RNQLFV8Yrg2lwjhIZKR8vEhF3WExPWx0lAYIAAAIAK//pAgECxQAZACUAagCyGAAAK7EgBOmyBgIAK7ENBOm0EhoYBg0rsRIE6bMKGAYIKwGwJi+wANaxHQXpsBAysB0QsSMBK7EVBemxJwErsR0AERKwDzmwIxG0CgYSDRgkFzmwFRKwCTkAsRogERKyABUQOTk5MDETND4DMzIWFyMuASMiBgc2MzIWFRQGIyITIgYVFBYzMjY1NCYrIjNHPyNRaw1YCz4uTFEBOmlfeoNl7vJBUlI+PVBKAUNej1IzEGJXMziLgk9+Y2iHAYJTQkRbV0NHUwAAAAABAC4AAAIIAsUACgA0ALIFAAArsgoCACuxCQTpAbALL7AF1rEEBemyBAUKK7NABAEJK7EMASsAsQoJERKwATkwMQEVBgIHIzYSNyE1Agh4ix1eKHx//oECxUqg/s+qrwEKtVcAAwAl/+kCAQLFABMAHgAoAHoAsgUAACuxJATpsg8CACuxFQTptBogBQ8NK7EaBOkBsCkvsAfWsSIF6bAMINYRsRcF6bAiELEnASuxAgXpsB0g1hGxEQXpsSoBK7EdFxESQAkEBQkODwAfICQkFzkAsSAkERKxBwI5ObAaEbEJADk5sBUSsREMOTkwMQEWFRQGIiY1NDcuATU0NjIWFRQGJiIGFRQWMzI2NTQGIgYUFjMyNjU0AYd6hdKFeTYqd7x3KnNwQ0M4N0Q5hFJRQUNTAXU6d2F6e2F2OiJAMVNqalMyQOE9MzI9PDI07E18Tk0/PgAAAAIAJv/pAf0CxQAYACMAcACyBgAAK7ENBOmyDQYKK7NADQkJK7IXAgArsRkE6bQSHwYXDSuxEgTpAbAkL7AU1rEcBemwHBCxIQErsBAysQAF6bElASuxHBQRErAJObAhEbUKBhESDRckFzmwABKwDzkAsRkfERKyABQQOTk5MDEBFA4DIyImJzMeATMyNjcGIiY1NDYzMgciBhUUFjI2NTQmAf0iM0dAI1FrDVgLPi5MUQFCwHqDZe/wPVBKgFNSAWtej1IzEGJXMziLgk9+Y2iHTVhDR1NUQUVbAAACAFAAAAC4AgwAAwAHADsAsgIAACu0AwQAHQQrsgcBACu0BgQAHQQrAbAIL7AC1rAGMrQBBQA6BCuwBDK0AQUAOgQrsQkBKwAwMTcVIzUTFSM1uGhoaGhoaAGkaGgAAP//AFD/bQC5AgwQJwARAAEBpBAGAA/5AAABAC3/9wIWAdoABgARALIGAAArAbAHL7EIASsAMDE3NSUVDQEVLQHp/nYBisZFz0+hpE8AAgAyAG8CFgFhAAMABwAgALAGL7QHBAA3BCuwAi+0AwQANwQrAbAIL7EJASsAMDEBFSE1BRUhNQIW/hwB5P4cAWFGRqxGRgAAAQAy//cCGwHaAAYAEQCyAgAAKwGwBy+xCAErADAxARUFNS0BNQIb/hcBiv52AQtFz0+hpE8AAAACAE0AAAH9AuUAGwAfAGsAsh4AACu0HwQAHQQrshkDACuxEgTpshIZCiuzQBIWCSsBsCAvsBbWsRUF6bAVELEeASuwCDKxHQXpsAYysB0QsQ8BK7EABemxIQErsR0eERKyDBIZOTk5sA8RsAQ5ALESHxESsQAHOTkwMQEUDgMdASM1ND4DNTQmIyIGFSM0NjMyFgMVIzUB/SU0NSVaJTU0JUY6SThVb2xhdLNaAiUuSjEtOSAvNyVCMDA9IzM/Ukpzd2j962hoAAIAIv9yA7cC5QAyAD4AjQCyIAMAK7ENBOmwGC+xEwTpsCovsCYztDMEAB8EK7AHMrA5L7QwBAAfBCsBsD8vsBzWsRAF6bAQELEtASuxPAXpsDwQsQoBK7EjBemxQAErsQo8ERJACQ0TFhggJiowNiQXOQCxExgRErAWObAqEbAVObE5MxEStwQKEBwjKC0yJBc5sDARsQEAOTkwMQEzAwYVFBYzMjY1NCYjIgYVFBYzMjcXBiMiLgE1ND4BMzIWFRQGIyInBiMiJjU0NjMyFwMyNjU0JiMiBhUUFgKZU1oMHhRAaNGPnuvYn09yHHByfNJ5heODr/uSfmAOQkxGXZxlVCa+QVs2KD9iOgH1/ugjDxIajlh9tuqdj8MgQypruG2A34TcmHq+TUhpTm2oV/7LpkwmNIJUMUUAAAACAA8AAAKLAtkABwAKACwAsgMAACuwBjOyBAMAK7QBCgMEDSuxAQTpAbALL7EMASsAsQQKERKwCTkwMSUhByMBMwEjCwIB2P7nTWMBBHgBAGhlcHjb2wLZ/ScBKQFM/rQAAAAAAwBQAAACcALZAA8AFQAfAGMAsgQAACuxHwTpsgUDACuxEwTptBQeBAUNK7EUBOkBsCAvsATWsR8F6bATMrAfELEaASuxAAXpsBEg1hGxCwXpsSEBK7ERHxESsA05ALEeHxESsAA5sBQRsA05sBMSsAs5MDElFAYjIREhMh4CFRQHHgEmNCsBFTMTMj4BNTQmKwEVAnB2Yf63ASg9Wi0UZUY/fZK0tC8xPhREP+PQXnIC2SQ7Ox9wLxtUjejo/rMrNB45RfsAAAABACj/6QKdAuUAHQBjALIYAAArsRIE6bISGAors0ASFQkrsgYDACuxDATpsgwGCiuzQAwJCSsBsB4vsADWsQ8F6bAPELEVASuxFgXpsAkg1hGxCAXpsR8BK7EJDxESsgYSGDk5OQCxDBIRErAAOTAxEzQ+AzMyFyMuASMiBhUUFjMyNjczAiEiLgMoETBHeUzuK18QXldqe4BtWmARYCH+9Ut3Ry8RAWQyYmpPNO5OTqKMiaFlav7fM05pYAAAAAACAFAAAAKSAtkABwAQADoAsgAAACuxCATpsgEDACuxEATpAbARL7AA1rEIBemwCBCxDAErsQUF6bESASsAsRAIERKxBAU5OTAxMxEhMhYQBiMnMzI2NTQmKwFQARmLnp+KvKxscHBsrALZwv6sw1KQiouQAAEAUAAAAlsC2QALAEoAsgQAACuxAQTpsgUDACuxCATptAkABAUNK7EJBOkBsAwvsATWsQEF6bAIMrIBBAors0ABAwkrs0ABBwkrs0ABCwkrsQ0BKwAwMRMVIRUhESEVIRUhFa0Brv31Afn+ZAGNAUz6UgLZUulSAAEAUAAAAjkC2QAJAEAAsgIAACuyAwMAK7EGBOm0BwACAw0rsQcE6QGwCi+wAtaxAQXpsAYysgECCiuzQAEFCSuzQAEJCSuxCwErADAxExEjESEVIRUhFa1dAen+dAFcAUz+tALZUulSAAAAAAEAKP/pAsEC5QAkAJsAsg8AACuyEgAAK7EGBOmyGwMAK7EiBOmyIhsKK7NAIh8JK7QLDBIbDSuxCwTpAbAlL7AV1rEABemwABCxCQErtA0FADwEK7IJDQors0AJCwkrsA0QsB4g1hGxHwXpsB8vsR4F6bANELQPBQARBCuwDy+xJgErsR8AERKyBhIbOTk5sAkRsBA5ALELBhESsBA5sAwRsQAVOTkwMRMUHgMzMjY9ASM1IREjJwYjIiY1ND4DMzIWFyMuASMiBoUOJDlePGSB3gEwOxdokZS6EjJLf1B9oRNfD3FTdIwBaiZNVD8pfmIUUv57YXTUqDBhalA1em9GUaMAAQBQAAACgQLZAAsAPwCyAwAAK7AKM7IEAwArsAgztAYBAwQNK7EGBOkBsAwvsAPWsQIF6bAFMrACELELASuwBzKxCgXpsQ0BKwAwMQEhESMRMxEhETMRIwIk/oldXQF3XV0BTP60Atn+xQE7/ScAAAEAZAAAAMIC2QADACEAsgIAACuyAwMAKwGwBC+wAtaxAQXpsQEF6bEFASsAMDETESMRwl4C2f0nAtkAAAEAI//pAbwC2QARAD8AsgkAACuxAATpsgAJCiuzQAANCSuyBAMAKwGwEi+wDNaxDwXpsA8QsQMBK7EGBemxEwErsQMPERKwCTkAMDE3MjY1ETMRFAYjIiY9ATMVFBbvQDBdb19ebV84N1RNAgH93V9uaFlAL0BEAAEAUAAAApMC2QALADAAsgIAACuwCTOyAwMAK7AGMwGwDC+wAtaxAQXpsAQysQ0BKwCxAwIRErEFCzk5MDETFSMRMxEBMwkBIwGtXV0Ba3j+1wEsbv7/AP//Atn+jwFx/tf+UAF2AAAAAQBQAAACFQLZAAUALACyBAAAK7EBBOmyBQMAKwGwBi+wBNaxAQXpsgEECiuzQAEDCSuxBwErADAxExEhFSERrQFo/jsC2f15UgLZAAEAUAAAAv4C2QAMAEYAsgQAACuxAAozM7IFAwArsAgzAbANL7AE1rEDBemwAxCxCwErsQoF6bEOASuxCwMRErEGCDk5ALEFBBESsgIHDDk5OTAxISMDESMRMxsBMxEjEQHZYs9YgdjUgVgCY/2dAtn9hQJ7/ScCYwAAAAABAFAAAAKKAtkACQBCALIFAAArsAEzsgYDACuwADMBsAovsAXWsQQF6bAEELEIASuxAQXpsQsBK7EIBBESsQIHOTkAsQYFERKxAwg5OTAxAREjAREjETMBEQKKaf6HWGUBfQLZ/ScCT/2xAtn9rAJUAAAAAAIAKP/pAugC5QAKABQARgCyAwAAK7EQBOmyCAMAK7ELBOkBsBUvsAbWsQ4F6bAOELESASuxAAXpsRYBK7ESDhESsQgDOTkAsQsQERKyBQYAOTk5MDEBFAYjIiYQNjMyFiUiBhAWMjY1NCYC6MCgnsLCnaDB/p90jo/oj44BYaLW0wFW09SCpf7ypaSEiqYAAAIAUAAAAl4C2QAKABIAQgCyBgAAK7IHAwArsRIE6bQECwYHDSuxBATpAbATL7AG1rEFBemwCzKwBRCxDwErsQAF6bEUASsAsRILERKwADkwMQEUBisBESMRITIWBTMyNjQmKwECXnFb5V0BLWx1/k/CQ0tLQ8ICA11x/ssC2W/jRHhEAAIAKP/FAugC5QAOABwAXQCyBAAAK7EZBOmyAAAAK7IJAwArsRUE6QGwHS+wB9axFwXpsBcQsRIBK7EMBemxHgErsRIXERKzAgkEDiQXObAMEbEBADk5ALEZBBESsAI5sBURswcGDgwkFzkwMQUHJwYjIiYQNjMyFhUUBycXNjU0JiIGEBYzMjcnAt8vaVZpnsLCnp3DZ55ZT4/oj450PDxKATpXM9MBVtPSqqxxgUlZi4alpf7ypRw+AAAAAgBQAAACmgLZAB0AJgB1ALIWAAArsAwzshcDACuxIgTptBQjFhcNK7EUBOkBsCcvsBbWsRUF6bAiMrAVELEPASuxCAXpsB4g1hGxGwXpshseCiuzQBsLCSuxKAErsQ8VERKwADmxCB4RErANOQCxFBYRErAFObAjEbAAObAiErAbOTAxAR4DFRQGFRQWFxUjJj0BNCYrAREjESEyFhUUBic0JisBFTMyNgILICsTBgESGnEUOj7wXQFQa3M2K0xD4eFKRQFoDiYwKh0JIggpOBIXLklBQz/+xgLZZV4+UoNINvs8AAAAAAEAMP/pAm0C5QAwAKAAsiQAACuxAATpsgAkCiuzQAAqCSuyDQMAK7EUBOmyFA0KK7NAFBAJKwGwMS+wCtaxFwXpsCog1hGxLAXpsBcQsQUBK7EeBemwESDWEbEQBemxMgErsDYauu/UwhQAFSsKDrAIELAHwLEaCfmwG8AAswcIGhsuLi4uAbMHCBobLi4uLrBAGgGxERcRErIADSQ5OTkAsRQAERKxCh45OTAxJTI+AjU0LwEmNTQ2MzIWFyMuASMiBhUUFh8BHgEVFA4DIyIuAyczFRQeAgFWOE4lD4a1j4t4fowBWAFeV0pZNkK3SlEPKD5nQSlLTjglAVgTK1U7GiopF1MjMCWFY3N3a0dNRDcqMBIxFGBDHTk9Lh4NIzdcPAUfNjQfAAAAAAEAHgAAAloC2QAHADoAsgIAACuyBQMAK7EEBOmwADIBsAgvsALWsQEF6bIBAgors0ABBwkrsgIBCiuzQAIECSuxCQErADAxAREjESM1IRUBa13wAjwCh/15AodSUgAAAAEAUP/pAoAC2QARADcAsgUAACuxDgTpsgkDACuwADMBsBIvsAjWsQsF6bALELERASuxAgXpsRMBK7ERCxESsAU5ADAxATMRFAYjIiY1ETMRFBYzMjY1AiNdmYCClV1lVVhkAtn+AG6CgW8CAP4AT09USgAAAQAPAAACdgLZAAYAIQCyAQAAK7ICAwArsAUzAbAHL7EIASsAsQIBERKwBDkwMSEjATMbATMBeWT++mTWymMC2f2XAmkAAAAAAQAPAAADmgLZAAwAdQCyBAAAK7EBAzMzsgUDACuyCAkLMzMzAbANL7EOASuwNhq6PcHvMgAVKwqwCC4OsAfAsQIE+QWwA8C6wmHuuAAVKwqwAS6xAwIIsALADrEKCvkFsAnAAwCyAgcKLi4uAbYBAgMHCAkKLi4uLi4uLrBAGgAwMSEjCwEjAzMbATMbATMC4Waoo2a7aImiZKaGaAJX/akC2f2wAlD9sAJQAAEADwAAAoIC2QALACYAsgUAACuwATOyBwMAK7AKMwGwDC+xDQErALEHBRESsQMJOTkwMQkBIwsBIwEDMxsBMwGAAQJzx8hxAQLycbu8bwF2/ooBMP7QAXYBY/7iAR4AAAEADwAAApcC2QAIADAAsgIAACuyBAMAK7AHMwGwCS+wAtaxAQXpsQoBK7EBAhESsAY5ALEEAhESsAY5MDEBESMRATMbATMBhV3+53PW0G8BHv7iAR4Bu/6dAWMAAQAeAAACSQLZAAkALACyBQAAK7ECBOmyCQMAK7EIBOkBsAovsQsBKwCxAgURErAGObAIEbABOTAxARUBIRUhNQEhNQJH/kwBtv3VAbb+ZgLZVP3NUlICNVIAAAABAED/LAD6AtkABwBAALIHAwArtAIEADcEK7AGL7QDBAA3BCsBsAgvsAbWtAUFAAsEK7AAMrQDBQA8BCu0BQUACwQrsAEysQkBKwAwMRMVIxEzFSMR+mdnugLZSPzjSAOtAAAAAf/4/+wBHALZAAMASQCyAgAAK7ABM7IDAwArsAAzAbAEL7AD1rQBBQAHBCuxBQErsDYausL77LEAFSsKsAMQsQAI+bABELECCPkDsQACLi6wQBoAMDEbASMDL+037QLZ/RMC7QAAAAABABb/LADQAtkABwBJALIFAwArtAQEADcEK7AAL7QBBAA3BCsBsAgvsADWsAQytAcFAAsEK7AHELQCBQA8BCuwAi+wBxC0AAUACwQrsAAvsQkBKwAwMRc1MxEjNTMRFmdnutRIAx1I/FMAAAABACwBSQGpAsUABgARALIAAgArAbAHL7EIASsAMDETMxMjCwEjxUmbRXp5RQLF/oQBLP7UAAAAAAH/6v9QAkL/ggADAB0AsAIvtAMEABMEK7QDBAATBCsBsAQvsQUBKwAwMQUVITUCQv2ofjIyAAAAAQAWAlAA5wLkAAMAIgCyAAMAK7QCBAAOBCsBsAQvsAPWtAEFAAoEK7EFASsAMDETFyMnh2A8lQLklJQAAgAe/+kCCwIbACkANAEYALINAAArsBIztAgEADcEK7AqMrICAQArsSYE6bImAgors0AmAAkrAbA1L7AV1rEzBemwMxCwKSDWEbEABemwAC+xKQXpsDMQsS0BK7AiMrQGBQA8BCuxNgErsDYaug74wcYAFSsKDrAbELAdwLExC/mwL8C6CNTAnQAVKwoOsBwQsB/AsTEvCLExDPmwL8CwGxCzHBsdEyuwHBCzHRwfEyu6CbHAvQAVKwuzHhwfEyuwMRCzMDEvEyuyMDEvIIogiiMGDhESObIeHB8REjkAtx8bHB0eLzAxLi4uLi4uLi4Btx8bHB0eLzAxLi4uLi4uLi6wQBoBsS0pERKyEgIqOTk5sAYRsBA5ALEmCBESswUQFS4kFzkwMRM2MzIWFREUMzI3FQYjIiYnBiMiJjU0Pgc3PgE9ATQmIyIGBxMyNj0BDgMUFjUGzGFkLQkJIxYoKQVUXk9dCQscEy0YPBwkMSY9ODo8BVNFWBllSjw2AXGqSUb+zCkCPwklKE1URxcmHRkQDwcKBAUGGhoWJigtMP7BSSpeDBAMLVAsAAACADz/6QIRAtkADgAZAF0Asg4AACuyCgAAK7EUBOmyAAMAK7IEAQArsQ8E6QGwGi+wANa0AgUAPAQrsBEytA0FACYEK7ACELEXASuxBwXpsRsBK7EXAhESsQQKOTkAsQ8UERKyBwIMOTk5MDETMxE2MzIWFRQGIyInFSMTIgYUFjMyNjU0JjxTOWloeHxoaztL5UJQUEJEVVMC2f7sVpR/gp1aQwHNb7hvb1lecAAAAAEAHv/pAdwCGwAYAGYAshAAACuxCgTpsgoQCiuzQAoNCSuyFgEAK7EEBOmyBBYKK7NABAEJKwGwGS+wE9axBwXpsAcQsQwBK7ABMrENBemwADKxGgErsQwHERKxEBY5ObANEbEYDjk5ALEEChESsBM5MDEBIy4BIyIGFRQWMzI3Mw4BIyImNTQ2MzIWAdZUCEA0RE1ORWsVVAhwXmt9f2pbbQFcNztvYl1qfmBrlX+CnGIAAAIAHv/pAfMC2QAPABsAYwCyAgAAK7IGAAArsRYE6bIPAwArsgwBACuxEATpAbAcL7AJ1rETBemwExCxGQErsA4ytAEFADwEK7ABELQCBQAbBCuwAi+xHQErsRkTERKxDAY5OQCxEBYRErIJDgM5OTkwMQERIzUOASMiJjU0NjMyFxEDIgYVFBYzMjY1NCYB80oiTzZqentmbDWTRFRURUJQUALZ/SdFMSuZhX2XUQEP/vRwW1xvbltebwAAAgAe/+kB9wIbABAAFgBuALIKAAArsQQE6bIECgors0AEBwkrsg8BACuxFQTptBEBCg8NK7QRBAArBCsBsBcvsA3WsQEF6bARMrABELESASuxAAXpsRgBK7ESARESsgYKDzk5ObAAEbAHOQCxAQQRErAMObEVERESsA05MDElIR4BMzI3Mw4BIyImEDYzMgUhNCYiBgH3/n4CUUdmI1QQdlpugINt6f6AASdSflLqUmJpVmCVAQKb7URcVwABABQAAAEEAtwAFABYALIEAAArsgwDACu0EQQAQwQrsgcBACuwADO0BgQAKwQrsAEyAbAVL7AE1rAIMrQDBQA8BCuwEzKyAwQKK7NAAwEJK7AOMrIEAwors0AEBgkrsRYBKwAwMQEVIxEjESM1MzU0NjMyFxUmIyIdAQEEV1NGRkE6FxgTCjoCDET+OAHIRFk4PwVFATVSAAIAHv8mAeoCGwAcACgAggCyAAAAK7EjBOmyCQEAK7IGAQArsR0E6bAQL7QWBAA3BCuyFhAKK7NAFhMJKwGwKS+wA9axIAXpsCAQsBQg1hGxEwXpsBMvsRQF6bAgELEZASuxCSYyMrELBemxKgErsRkUERK0AAYQHSMkFzmwCxGwCDkAsR0jERKyAwgaOTk5MDEXIiY1NDYzMhcnMxEUDgIjIiYnMxYzMjY9AQ4BAyIGFRQWMzI2NTQm9lx8e2RiPgpXEjBfSVxuB1UOcVQ+I0shQ05OREJMSxeXfYCeW0z+SktlVipUSlhfYRsyLAHlbl5fbWteYm0AAQA8AAAB3ALZABMAUACyCAAAK7ASM7IJAwArsg4BACu0AwQAQwQrAbAUL7AI1rQHBQA8BCuwCjKwBxCxEwErtBIFADwEK7EVASuxEwcRErAOOQCxAwgRErALOTAxATQmIyIGFREjETMRPgEzMhYVESMBiUMpQE5TUyVLOExZUwFrNzBhUP7fAtn+6zAnTUL+dAAAAAIAQgAAAJYC2QADAAcAOQCyAgAAK7IHAwArtAYEAB0EK7IDAQArAbAIL7AC1rAGMrQBBQA8BCuwBDK0AQUAPAQrsQkBKwAwMRMRIxE3FSM1llNTVAIM/fQCDM1paQAAAAIAAP8mAKsC2QAMABAANwCyEAMAK7QPBAAdBCuyAAEAK7AEL7QJBAA3BCsBsBEvsAzWsA8ytAIFADwEK7ANMrESASsAMDETMxEUIyInNRYzMjY1ExUjNVhTjw0PDAskHVNTAgz9h20DRwIfJwMlaWkAAAAAAQA8AAAB+ALZAAsANQCyCgAAK7AFM7ILAwArsgIBACsBsAwvsArWtAkFADwEK7AAMrENASsAsQIKERKxAQc5OTAxExE3MwcTIwMHFSMRj95rttZnsVFTAtn+Vd61/qkBHFDMAtkAAAABADwAAACQAtkAAwAhALICAAArsgMDACsBsAQvsALWsQEF6bEBBemxBQErADAxExEjEZBUAtn9JwLZAAABADwAAALwAhsAIQBvALIhAAArsQ4XMzOyAAEAK7IFAQArsAoztBwEAEMEK7ATMgGwIi+wIdaxIAXptAIFACYEK7AgELEYASuxFwXpsBcQsQ8BK7EOBemxIwErsRggERKwBTmwFxGwBzmwDxKwCjkAsRwhERKxBwI5OTAxEzMVPgEzMhc+ATMyFhURIxE0JiMiBhURIxE0JiMiBhURIzxNIks0YSwlSDRJT1QzLjNIVDMuM0hUAgxKLypQLCRLR/53AWkyN1A5/rcBaTI3UDn+twAAAAEAPAAAAd0CGwATAFEAshMAACuwCTOyAAEAK7IFAQArtA4EAEMEKwGwFC+wE9axEgXptAIFACYEK7ASELEKASu0CQUAPAQrsRUBK7EKEhESsAU5ALEOExESsAI5MDETMxU+ATMyFhURIxE0JiMiBhURIzxNI1E6TFpTOjJATlQCDFg3ME5B/nQBay84YVD+3wAAAAACAB7/6QH4AhsACgAVAEYAsgYAACuxEATpsgABACuxCwTpAbAWL7AJ1rEOBemwDhCxEwErsQMF6bEXASuxEw4RErEABjk5ALELEBESsggJAzk5OTAxATIWFRQGIyImEDYXIgYUFjMyNjU0JgEKcX1/bnB9fm9GUFBGRVFPAhuViIGUlQEIlU1tvm1tXGFuAAACADz/JgIRAhsADgAZAGQAsgsAACuxFATpsgsUCiuzQAsACSuyAQEAK7IFAQArsQ8E6QGwGi+wANaxDgXpsBEytAMFACYEK7AOELEXASuxCAXpsRsBK7EXDhESsQsFOTkAsRQLERKwDTmwDxGxCAM5OTAxFxEzFTYzMhYVFAYjIicREyIGFBYzMjY1NCY8TTtsaHl7ZWFAkkJQUEJEVFPaAuZPXpqEfZdO/u8Cp2+4b29ZXnAAAAAAAgAe/yYB8wIbAA4AGgBpALIEAAArsRUE6bIEFQors0AEAQkrsg0BACuyCgEAK7EPBOkBsBsvsAfWsRIF6bASELEBASuwGDK0AAUAPAQrsAAQtAwFABsEK7AML7EcASuxARIRErEECjk5ALEPFRESsgcCDDk5OTAxBSMRBiMiJjU0NjMyFzUzByIGFRQWMzI2NTQmAfNTOWloeHxoazxK5UVUVEVCUE/aARZTlH+CnVVGP3BbXG9uWl5wAAABADwAAAE4AhsADQA1ALIFAAArsgYBACuyCwEAK7EABOkBsA4vsAXWsQQF6bQIBQAmBCuxDwErALEABRESsAg5MDEBDgEVESMRMxU+ATMyFwE4VFRUTSRDKAsVAcMCSmf+8AIMXzszAwAAAAABACL/6QHLAhsAJAC1ALIiAAArsQME6bIDIgors0ADJAkrshABACuxFQTpshUQCiuzQBUSCSsBsCUvsA3WsRgF6bAYELAAINYRsSQF6bAkL7EABemwGBCxBgErsR8F6bAfELASINYRsRMF6bATL7ESBemxJgErsDYauvDawdEAFSsKDrAKELAJwLEbBPmwHMAAswkKGxwuLi4uAbMJChscLi4uLrBAGgGxExgRErMDDxAiJBc5ALEVAxESsQ0fOTkwMTceATMyNjU0Ji8BLgE1NDYyFhcjJiMiBhUUFh8BHgEVFAYjIid6BjVFN0MmK05dSW62YgFYA2YzPC4zUE5GdWPLBpwvNy0lHSIKExZDPklXVE1UKyQcIwwTE0U6TFqzAAAAAQAU/+kBBAKcABUAZgCyCwAAK7QGBABDBCuyEQEAK7AAM7QQBAArBCuwATKyERAKK7NAERQJKwGwFi+wDtawEjK0AwUAPAQrsBQysgMOCiuzQAMBCSuwCDKyDgMKK7NADhAJK7EXASsAsRAGERKwCDkwMQEVIxEUFjMyNxUGIyImNREjNTM1MxUBBFYTGxkPJx0xNEdHUwIMRP6ZHBMERgcrKAGMRJCQAAAAAAEAPP/pAd0CDAATAFoAsgEAACuyBQAAK7QOBABDBCuyCQEAK7ASMwGwFC+wCNa0CwUAPAQrsAsQsREBK7QABQA8BCuwABC0AQUAJgQrsAEvsRUBK7ERCxESsAU5ALEJDhESsAI5MDEhIzUOASMiJjURMxEUFjMyNjURMwHdSyVQOkxbUzoyQU5TSTQsTkEBlP6NLzhhUAEpAAAAAAEACgAAAeYCDAAGACEAsgEAACuyAgEAK7AFMwGwBy+xCAErALECARESsAQ5MDEhIwMzGwEzAR1buF6MlF4CDP5XAakAAQAKAAACyAIMAAwAdQCyBAAAK7EBAzMzsgUBACuyCAkLMzMzAbANL7EOASuwNhq6PifwugAVKwqwCC4OsAfAsQIH+QWwA8C6wgfwBAAVKwqwAS6xAwIIsALADrEKDfkFsAnAAwCyAgcKLi4uAbYBAgMHCAkKLi4uLi4uLrBAGgAwMSEjCwEjAzMbATMbATMCLl9qZV6YXGtkZmdoXgGb/mUCDP5oAZj+aAGYAAEACgAAAdICDAALACYAsgUAACuwATOyBwEAK7AKMwGwDC+xDQErALEHBRESsQMJOTkwMQETIycHIxMDMxc3MwEdtWGDhV+5r19+fl4BD/7xyckBCwEBvr4AAAAAAQAK/yYB1AIMABAAWwCyDgEAK7EADzMzsAQvsQkE6QGwES+xEgErsDYausMy7AgAFSsKsA4uDrANwAWxDwr5DrAQwACxDRAuLgGzDQ4PEC4uLi6wQBoBALEJBBESsAY5sA4RsAc5MDEBMwMGIyInNRYzMjY/AQMzEwF6WukpXh8ZGxEaHgsgsVmGAgz9hmwNSwYXHFMCDv5oAAAAAQAeAAAByAIMAAkALgCyBQAAK7QCBABDBCuyCQEAK7QIBABDBCsBsAovsQsBKwCxCAIRErEBBjk5MDEBFQEhFSE1ASE1Abr+yQFF/lYBOf7cAgxK/odJSwF4SQABACv/LAEUAtkAIQBKALIhAwArtAIEACsEK7ASL7QPBAArBCsBsCIvsBXWsB0ytAwFACYEK7AFMrIMFQors0AMEQkrsAAysSMBKwCxAg8RErEVHjk5MDEBFSMiBh0BFAYHFh0BFBY7ARUjIiY9ATQmJzU+AT0BNDYzARQPJRokLlIaJQ8uNDkiLCwiOTQC2UEcJ7VFRhImeLUnHEFFPqdFPAlFCTtGpz5FAAAAAQBf/ywAmwLZAAMAIgCyAAMAKwGwBC+wA9a0AgUAGwQrtAIFABsEK7EFASsAMDETMxEjXzw8Atn8UwAAAQA5/ywBIgLZACAASgCyEAMAK7QPBAArBCuwAC+0AQQAKwQrAbAhL7AF1rAKMrQdBQAmBCuwFDKyBR0KK7NABQAJK7APMrEiASsAsQ8BERKxFB05OTAxFzUzMjY9ATQ3Jj0BNCYrATUzMhYdARQWFxUOAR0BFAYjORAlG1JSGyUQLzQ6ISsrITo01EEcJ7V4JSZ4tSccQUU+p0U8CUUJPEWnPkUAAAAAAQAhAQwB0gG2ABUAdACwES+0CwQAKwQrsgsRCiuzQAsPCSuwAC+0BgQAKwQrsgAGCiuzQAADCSsBsBYvsAPWtAIFABEEK7ACELEOASu0DwUAEQQrsRcBK7ECAxESsAQ5sA4RsQYROTkAsQsRERKwEzmwABGxCRQ5ObAGErAIOTAxEyIHIz4BMzIfARYzMjY1MxQjIi8BJosvBjUENzEbG3UcFh4VNWknKmIXAXNORksQRRElJo8aPw4AAP//AAAAAAAAAAAQAgADAAD//wB6/zMAzgIMEA8ABAFKAgzAAAACADT/iAH+AnQAGQAfAI8AsgcAACuwCjOxAQTpsBoysgcBCiuzQAcJCSuyAQcKK7NAAQQJK7IQAQArsBMzsRsE6bAAMrIQGwors0AQEQkrAbAgL7AN1rEdBemwHRCxCQErsRAaMjK0CAUAEQQrsQASMjKwCBCxAwErsBcysQQF6bAWMrEhASuxBAMRErEFFTk5ALEbARESsQ0WOTkwMQERNjczDgEHFSM1LgE1NDY3NTMVHgEXIy4BAxEGFRQWAThgElQFalcqZXV1ZSpYYwVUBTlYg0UBzv5nC3RabQRhYgmTd3qYC1pZBmNWMjz+bQGWGLhVZwAAAAEAGv/pAhcC2QA1ANAAshsAACuyFgAAK7QRBABCBCuyKgMAK7EzBOmyMyoKK7NAMzAJK7EZFhAgwC+xDgTpsBMytCIjFioNK7AEM7QiBAAfBCuwBjIBsDYvsCfWsQAF6bInAAors0AnIgkrsAAQsR8BK7EJBemyCR8KK7NACQYJK7AJELExASuxMAXpsTcBK7EAJxESswwbISQkFzmxCR8RErMDBAcZJBc5sDERtA4RFiozJBc5sDASsBM5ALERGRESsgwUHDk5ObEiDhESsQkfOTmxMyMRErAnOTAxExQeARczFSMWFRQGBzYzMhYzMjcXBiMiJiMiByc+ATU0JyM1My4BNTQ2MzIeAxcjJiMiBpMPJgagiA8zQzs/IWgYKCsqOUorhiM1ODBFOBhuUSITiWUdNT4sHwFYBIRATQILHCw+DTcrHCdSRCcfHkI4LiVCO1YuJig3OTEhW3sJHjFXOZpGAAAAAAIAQwCFAekCJwAbACYAeACwBC+xIQTpsBwvsRIE6QGwJy+wC9a0HwUAJgQrsB8QsSQBK7QZBQAmBCuxKAErsR8LERKzBwkNDyQXObAkEbMCBhAUJBc5sBkSsxUBFxskFzkAsSEEERKzAAIGCCQXObAcEbMJDRcbJBc5sBISsw4QFBYkFzkwMSUHJwYjIicHJzcmNTQ3JzcXNjMyFzcXBxYVFAcnIgYUFjMyNjU0JgHlOjUoPDUpMzgwICA2ODcsNTooOzk3Gh2dLD4/LCs/Pr42NR4ZMzkxKzs5LTc1NxocNTo3KTQyL8k+Vj09Kiw+AAEACwAAAiECxQAWAHoAsggAACuyEQIAK7AUM7QKCwgRDSuwAzO0CgQAEwQrsAUytA4PCBENK7AAM7QOBAATBCuwATIBsBcvsAjWsAwysQcF6bACMrIHCAors0AHBQkrsAAysggHCiuzQAgKCSuwDjKxGAErsQcIERKwEzkAsREPERKwEzkwMQEVIxUzFSMVIzUjNTM1IzUzAzMbATMDAe+qqqpYrKysl81VubNVyQFiM00zr68zTTMBY/6+AUL+nQAAAAACAGT/LACgAtkAAwAHACgAsgADACsBsAgvsAfWsAAytAYFABsEK7ABMrQGBQAbBCuxCQErADAxEzMRIxUzESNkPDw8PALZ/m+L/m8AAgAr/ysB+gLZADQAPwDZALI0AAArsgcAACuyKgAAK7IUAwArsRwE6bAuL7EDBOmzGDQUCCsBsEAvsAzWtD4FACYEK7A0INYRsQAF6bMRPgwIK7EfBemwPhCxOAErtCYFACYEK7MrJjgIK7EGBemwBi+xKwXpsCsQsBcg1hGxGAXpsBgvsRcF6bFBASuxETQRErAKObEAPhESsQkPOTmwHxGwOzmwBhK2AwgTHCIuNiQXObAYEbAUObA4ErEjKDk5sRcrERKwJDkAsTQDERKxBis5ObAYEbMPIjY7JBc5sBwSsREfOTkwMRcUFjMyNjU0LwEuATU0NjcmNTQ2MhYdASM1NCYjIgYVFBYfAR4BFRQHHgEVFAYjIi4DNTcXNjU0LwEOARQWoj0pKzU3qjErMjcsa5xhVDUsJjMZIJI9MG0eF2tQGC40JxlvpklJoScgGg5FNTAmMiZ1IkoxMkcdMzNFYGJPHBovNzAlFiIVXidKNnMpIjQgSGAIGypKMPN7Jz89M20aLTwoAAD//wAZAmQBNALMECYCfFkAEAYCfKYAAAD//wAn//IC+QLEEC8U2gCyAIo0ehAGD3QAAAAAAAMAJQEvAU0C5gADACMALQCVALACL7QDBAATBCuwCy+wBzO0KgQAEwQrsQQiMjKwFy+0HQQAEwQrshcdCiuzQBcbCSsBsC4vsA7WtCgFABEEK7AbINYRtBoFABEEK7AoELEtASuwFDK0IAUAEQQrsS8BK7EbDhESsQMCOTmxLRoRErQLER0mKiQXObAgEbAJOQCxKgsRErAJObAXEbMOHyAkJBc5MDEBFSE1JRUGIyInBiMiJjU0Njc+AT0BNCMiBgcjNjMyHQEUMzInDgIVFDMyNjUBQP7rASIQEC8IMTgwOERZHBVDIh0FOwN+ehcEVBNTLjklNgFiMzNfLAYrKzQsMTEHAg4RDSwYIGxesxd6CAoXHS8oGgACAEcAagGsAbYABgANABwAsAYvsA0ztAIEAAcEK7AJMgGwDi+xDwErADAxNzU3FQcXFTc1NxUHFxVHmGpqNZhqauNZelNTU1N5WXpTU1NTAAEAKABWAiABdwAFADYAsAUvtAAEADcEK7IFAAors0AFAwkrAbAGL7AD1rQCBQAbBCuyAwIKK7NAAwUJK7EHASsAMDETIREjNSEoAfhG/k4Bd/7f2wAAAP//AC4A8AEfATgQBgAQAAD//wAn//IC+QLEEC8U6QC+AIc0ehAGD3QAAAAAAAEAHAJ3AS4CvQADAC8AsgMCACu0AgQANwQrsgMCACu0AgQANwQrAbAEL7ECASu0AQUACAQrsQUBKwAwMQEVITUBLv7uAr1GRgAAAAACAJcBfwHGAq4ACgAVAE4AsAYvtBEEAB8EK7AML7QABAAfBCsBsBYvsAnWtA4FABEEK7AOELEUASu0AwUAEQQrsRcBK7EUDhESsQYAOTkAsQwRERKyCAkDOTk5MDEBMhYVFAYjIiY0NhYiBhUUFjMyNjU0AS8+WVlAPVlZZk44NyYoOAKuWT5AWFp8WTk4Jic4NygnAAAA//8AMv/1AhYCbxAnDcoAAP8wEAcADgAAAJUAAAABABMBhgFGAy8AHABfALAUL7QRBAAfBCuwAC+0CAQAEwQrsgAICiuzQAAGCSsBsB0vsAbWtAUFABsEK7ARMrAFELEaASu0CwUAGwQrsBIysR4BK7EaBRESsggNFzk5OQCxABERErELFzk5MDETIg4CByM2MzIWFRQPAQ4BBzMVIT4BPwE2NTQmshokEQcBPgSTQFJgPyEfCeX+0AQzSDo7MQL6EiAdFJhGOFIvIBEjHDpJTCYfIC8gKwAAAAEAEAF6AUIDMQAlAJcAsBAvtBcEABMEK7IXEAors0AXEwkrsB8vtCAEABMEK7AAL7QGBAATBCuyAAYKK7NAAAQJKwGwJi+wBNa0AwUAGwQrsBMg1hG0FAUAGwQrsAMQsRoBK7QNBQAbBCuwIyDWEbQJBQAbBCuxJwErsSMDERKzBhAXHyQXObAaEbALOQCxHxcRErANObAgEbALObAAErAJOTAxEyIGFSM2MzIWFRQHFhUUBiMiJjUzHgEzMjY1NCYnJiM1MjY1NCapLiM/A41ASzlHVUZITz4CLC0qMCAaDzNALikC/C0sjkA4OxoYTD1JSkQuKysmGycEAjMaIyAkAAAAAQBcAlABLQLkAAMAIgCyAAMAK7QDBAAOBCsBsAQvsAPWtAEFAAoEK7EFASsAMDETMwcjvHGVPALklAAAAQBB/yQCIAIMABoAZQCyAwAAK7AHM7QZBAA3BCuwETKyAxkKK7NAAwsJK7IMAQArsBUzAbAbL7AL1rQKBQA8BCuwDTKwChCxFAErsAUytBcFADwEK7EcASuxFAoRErAHOQCxGQMRErAJObAMEbAFOTAxJRUGIyInBiMiJxUjETMRFBYzMjY1ETMRFDMyAiAhGFMDO2g2JFNTOjFBTlMtCDE/CVNTGt8C6P6NLzhhUAEp/kwpAAAAAAEAMP9PAgoC2QAPAFkAsgYDACu0DQQAHwQrsAgysg0GCiuzQA0PCSuwCjIBsBAvsA/WtA4FABsEK7AOELQDBQAIBCuwAy+wDhCxCwErtAoFABsEK7IKCwors0AKBwkrsREBKwAwMQEuATU0NjsBFSMRIxEjESMA/2Fugl76OUBSQAEDBYNeZYtA/LYDSvy2//8AVwDjAL8BSxADAnz/5P5/AAAAAQAn/yoBHwAAABoAQgCyDgAAK7AYL7QFBAATBCuwCi+0EgQAEwQrAbAbL7AI1rQVBQAmBCuxHAErALEFGBESsBo5sAoRswAMDRUkFzkwMRceAzMyNjU0IyIHJzczBzYzMhYVFAYjIic8CSERGg0XHy4PEAwqJhcNDyYpQjkvTowEEAcGGhMlCAdcOAIjICsyIgAAAAEARQGGAOYDLwAJAEUAsgIDACu0AQQAEwQrsgIBCiuzQAIGCSsBsAovsAnWtAgFABsEK7IJCAors0AJAQkrsAgQtAYFABEEK7AGL7ELASsAMDETIzU3PgE3MxEjqGMPNiQNKz4Cri4BBR0w/lcAAAADACgBLwFEAuYAAwAOABkAaACwAi+0AwQAEwQrsAovtBUEABMEK7APL7QEBAATBCsBsBovsAzWtBIFABEEK7ASELEXASu0BwUAEQQrsRsBK7ESDBESsQMCOTmwFxGyCQoEOTk5sAcSsQEAOTkAsQ8VERKxBww5OTAxARUhNRMyFhUUBiImNTQ2FyIGFRQWMjY1NCYBOv75g0RKS4ZLS0MnLS1OLSwBYjMzAYRaVE9aWlJRWjRANzhAPzc5QAAAAP//AEgAagGtAbYQDwBtAfQCIMAAAAQAPf/sA1EC1gAJAA0AGAAbAMoAshgAACuwDDOyCgIAK7QPGwwKDSuwEzO0DwQAEwQrsBUyshsPCiuzQBsRCSuxAgoQIMAvtAEEABMEK7ICAQors0ACBgkrAbAcL7AJ1rQIBQAbBCuyCQgKK7NACQEJK7AIELQGBQARBCuwBi+wCBCxGAErsBkytBcFABsEK7ASMrIXGAors0AXFQkrshgXCiuzQBgPCSuxHQErsQgGERKwDTmwGBGzCgsMGyQXObAXErAROQCxARsRErIIEBo5OTmxCgIRErADOTAxEyM1Nz4BNzMRIwEzASMlIzUTMxEzFSMVIz0BB6BjDzYkDSs+AeM6/jw6AhG8zC5DQz6BAlUuAQUdMP5XAZj9J3g7AQr+8DVkmaqqAAAAAAMAPf/sA0wC2QAJAA0AKgDJALINAAArsiIAACu0HwQAHwQrsgYDACuyCgIAK7QWDg0KDSu0FgQAEwQrsg4WCiuzQA4UCSuxAgoQIMAvtAEEABMEKwGwKy+wCda0CAUAGwQrsgkICiuzQAkBCSuwCBC0BgUAEQQrsAYvsAgQsRQBK7QTBQAbBCuwHzKwExCxKAErtBkFABsEK7AgMrEsASuxBgkRErANObEUCBESsgwiIzk5ObEoExEStAoLFhslJBc5ALEOHxESswkIGSUkFzmxCgIRErADOTAxEyM1Nz4BNzMRIwEzASMBIg4CByM2MzIWFRQPAQ4BBzMVIT4BPwE2NTQmoGMPNiQNKz4Byzr+PDoCERokEQcBPgSTQFJgPyEfCeX+0AQzSDo7MQJYLgEFHTD+VwGV/ScBiBIgHRSYRjhSLyARIxw6SUwmHyAvICsAAAAEABr/7ANEAt4AJQApADQANwEXALI0AAArsCgzsgYDACu0AAQAEwQrsgAGCiuzQAAECSuyJgIAK7QrNygmDSuwLzO0KwQAEwQrsDEysjcrCiuzQDctCSu0EBcoJg0rtBAEABMEK7IXEAors0AXEwkrtCAfKCYNK7QgBAATBCsBsDgvsATWtAMFABsEK7ATINYRtBQFABsEK7ADELEaASu0DQUAGwQrsCMg1hG0CQUAGwQrsA0QsTQBK7A1MrQzBQAbBCuwLjKyMzQKK7NAMzEJK7I0Mwors0A0KwkrsTkBK7EjAxEStQYQFx8oKSQXObAaEbALObE0DRESsiYnNzk5ObAzEbAtOQCxEDcRErAsObAXEbA2ObAfErANObAgEbALObAAErAJOTAxEyIGFSM2MzIWFRQHFhUUBiMiJjUzHgEzMjY1NCYnJiM1MjY1NCYlMwEjJSM1EzMRMxUjFSM9AQezLiM/A41ASzlHVUZITz4CLC0qMCAaDzNALikBqjr+PDoCB7zMLkNDPoECqS0sjkA4OxoYTD1JSkQuKysmGycEAjMaIyAkHP0neDsBCv7wNWSZqqoA//8AYP8nAhACDBAPACICXQIMwAD//wAPAAACiwOEECcYWAC0AAASAgAkAAD//wAPAAACiwOEECcYWQEEAAASAgAkAAD//wAPAAACiwOEECcYWgCqAAASAgAkAAD//wAPAAACiwN3ECMCfwCvAKoSAgAkAAD//wAPAAECiwNxECMAagCuAKUSAgAkAAH//wAPAAACiwPGECMCfQCoAMISAgAkAAAAAgAPAAADugLZAA8AEwBeALIPAAArsAIzsQwE6bIEAwArsRIE6bAGMrQBEw8EDSuxAQTptAgLDwQNK7EIBOkBsBQvsA/WsBAysQwF6bAHMrIMDwors0AMBQkrs0AMCgkrs0AMDgkrsRUBKwAwMSUhByMBIRUhFSEVIRUhFSEZASMDAdj+81VnASsCbv6NAWD+oAGF/h5kitbWAtlS6VL6UgEoAV/+oQAAAQAo/yoCnQLlADcApQCyBgAAK7EABOmyAAYKK7NAAAMJK7IgAAArsiwDACuxMgTpsjIsCiuzQDIvCSuwDy+0FwQAEwQrsBwvtAkEABMEKwGwOC+wJtaxNQXpsDUQsRoBK7QMBQAmBCuwDBCxAwErsQQF6bAvINYRsS4F6bE5ASuxGjUREkAKBgAJDwcRHyAsMiQXOQCxFw8RErARObAcEbMMEh4fJBc5sTIAERKwJjkwMSUyNjczAiEHNjMyFhUUBiMiJzceAzMyNjU0IyIHJzcuAScuATU0PgMzMhcjLgEjIgYVFBYBclpfEmAh/vcNDQ8mKUI5ME0VBx8SHA4XHy4PEAsfODwhREwRMEd5TO4rXxBcWGt7gDpkbP7fIQIjICsyIigDDwgHGhMlCAdFCBUXMaxqMmJqTzTuTU+ijImiAAD//wBQAAACWwOEECcYWAC+AAASAgAoAAD//wBQAAACWwOEECcYWQDmAAASAgAoAAD//wBQAAACWwOEECcYWgCqAAASAgAoAAD//wBQAAACWwN0ECMAagCqAKgSAgAoAAD//wAAAAAA5QOEECYYWPQAEAYALAAAAAD//wAxAAABFgOEECYYWSgAEAYALAAAAAD//wAKAAABKQOEECYYWvYAEAYALAUAAAD//wAIAAABIwNyECYALAAAEAMAav/vAKYAAgAUAAACmwLZAAsAFwB0ALILAAArsQ0E6bIEAwArsRQE6bQCAQsEDSuwDDO0AgQAKwQrsBUyAbAYL7AL1rADMrENBemwFDKyDQsKK7NADRcJK7ILDQors0ALAQkrsA0QsREBK7EIBemxGQErALEBDRESsQgQOTmxFAIRErEHETk5MDETIzUzESEyFhAGIyETETMyNhAmKwEVMxVZRUUBGoqenor+5l2ta3Bwa62rAVNDAUPC/qzDAVP+/5ABFo/xQwAA//8AUAAAAooDZhAjAn8AxwCZEgIAMQAA//8AKP/pAugDhBAnGFgA5gAAEgIAMgAA//8AKP/pAugDhBAnGFkBNgAAEgIAMgAA//8AKP/pAugDhBAnGFoA5gAAEgIAMgAA//8AKP/pAugDchAjAn8A4wClEgIAMgAA//8AKP/pAugDdBAjAGoA4gCoEgIAMgAAAAEAXwAiAegBqwALAAABFwcXBycHJzcnNxcBtjGSkzKTkjKTkjGSAasykpMyk5Ixk5IxkQADACP/6QLtAvMAEwAbACMAcACyEAAAK7ATM7EfBOmyBgMAK7EXBOkBsCQvsAPWsRoF6bAaELEiASuxDQXpsSUBK7EaAxESsQETOTmwIhG1CBASBhUdJBc5sA0SsQkLOTkAsR8QERKwADmwFxG2AQsNAxIUHCQXObAGErEICjk5MDE/ASY1NDYzMhc3FwcWFRQGIyInBzcBJiMiBhUUCQEWMzI2NTQjUUzDnYldVyhZVMOdkGFNaQGASWJ0jwHR/n1Ka3SPE1lqkqrTUV8kYWqeqtNaVMEBo0ClhmgBKv5bSqWGcv//AFD/6QKAA4QQJxhYANIAABICADgAAP//AFD/6QKAA4QQJxhZAQ4AABICADgAAP//AFD/6QKAA4QQJxhaAMgAABICADgAAP//AFD/6QKAA3ESIgA4AAAQAwBqAMoApf//AA8AAAKXA4QQJxhZAPoAABICADwAAAACAFAAAAJdAtkADAAUAEkAsgIAACuyAwMAK7IUAQArsQUE6bQADQIFDSuxAATpAbAVL7AC1rEBBemxBA0yMrABELERASuxCQXpsRYBKwCxFA0RErAJOTAxNxUjETMVMzIWFRQGIyczMjY0JisBrV1d0Gh4clnlwkFJSUHCvb0C2XhxY1t1UkR4RAAAAAEAUP/oAioC2AAmAHoAsgkAACuyGwAAK7EgBOmwJi+0AAQAQwQrsAUvsQ0E6QGwJy+wCdaxCAXpsAgQsSMBK7EYBemwAiDWEbEQBemyAhAKK7NAAiYJK7EoASuxAggRErMNGx0gJBc5sCMRsBU5ALEmIBESsRgeOTmwABGwFTmwBRKwEDkwMQEyNTQmIyIVESMRNDYzMhYVFA4CBx4BFRQGIyInNRYzMjY1NCYjARWbSTuEWHVoZnURIREPNECDZSApHyFDU15cAatxMT+O/gICFFhsYlIiNiQOCg5mMn6EEEsLVEpQPP//AB7/6QILAuQQIgBDawASAgBEAAAAAP//AB7/6QILAuQQIgB2XAASAgBEAAAAAP//AB7/6QILAtcQIgJpcPISAgBEAAAAAP//AB7/6QILAsUQIgJ/cfgSAgBEAAAAAP//AB7/6QILAtcQIgBqcAsSAgBEAAAAAP//AB7/6QILAwQQIgJ9bAASAgBEAAAAAAADAB7/6QNJAhsALwA7AEIAzACyEgAAK7ALM7QwBABDBCuwBTKyMBIKK7NAMAgJK7IlAQArsCozsSAE6bBAMrIgJQors0AgIwkrtDwAEiUNK7Q8BAArBCsBsEMvsBXWsTkF6bA5ELAiINYRsSMF6bAjL7EiBemwORCxMwErsB0ytAAFACYEK7A8MrAAELE9ASuxLwXpsUQBK7EzIhEStBsSJTA3JBc5sAARsQ8nOTmwPRKyBwsqOTk5sC8RsAg5ALEAMBESsg8VNzk5ObA8EbEaNDk5sCASsRsnOTkwMSUeAzMyNzMOASMiJyY1DgEjIiY1ND4FPQE0IyIHIzYzMhc+ATMyFhcWFQUyNj0BDgMVFBYlITQmIyIGAccBHjAxGmUlVBB2WYg4AjhlO0xcGipGR2YkdnAKVAbKgC8bXDZJcBoV/ZBGWh5nRzg2AR4BJlBAP1LqNEslEGlVYWsCATo0VEcmOSQYDAgaHRZOXapSJixKQDdwuFEaZQ0RCiwoJy38R1lXAAAAAAEAHv8qAdwCGwA1ALIAshwAACuxFgTpshYcCiuzQBYZCSuyAAAAK7IJAQArsRAE6bIQCQors0AQDQkrsCUvtC0EABMEK7AyL7QfBAATBCsBsDYvsAbWsRMF6bATELEwASu0IgUAJgQrsCIQsRgBK7ANMrEZBemwDDKxNwErsRMGERKwJzmwMBFACgkQABYcHR8lKDUkFzmxGRgRErELGjk5ALEtJRESsCc5sDIRsyIoNDUkFzmxEBYRErAGOTAxFy4ENTQ2MzIWFyMuASMiBhUUFjMyNzMOASMHNjMyFhUUBiMiJzceAzMyNjU0IyIHJ+A1TiYVBH9qW20HVAhANERNTkVrFVQFdFwNDg4lKkI5L04VBx8RHQ4XHy4PEAwVCjg9UCwXgpxiXTc7b2Ndan9ebSECIyArMiEpAw8IBxoTJQgH//8AHv/pAfcC5BAiAENvABICAEgAAAAA//8AHv/pAfcC5BAiAHZqABICAEgAAAAA//8AHv/pAfcC1xAiAmlx8hICAEgAAAAA//8AHv/pAfcC1xAiAGprCxICAEgAAAAA//8AAAAAANEC5BAiAEPqABICAPMAAAAA//8ADQAAAN4C5BAiAHaxABICAPMAAAAA////9AAAARMC1xAmAPMUABACAmng8gAA////9QAAARAC2BAmAPMUABACAGrcDAAAAAIAHv/pAfgC5wAfACoAVwCyHgAAK7ElBOmyBgEAK7EgBOkBsCsvsADWsSMF6bAjELEoASuxGwXpsSwBK7EjABESsgsMDzk5ObAoEUAJBgoNEBQIHR4VJBc5ALEgJRESsRsAOTkwMRM0PgMzMhcmJwcnNyYnNxYXNxcHHgQVFAYiJhMiBhQWMzI2NTQmHh0tPDgcGCcnO2EkVR40LCVKYShaHipGKyJ84nztRlBQRkVRTwECQGU8Jw8NKDEtJygXHSwQLy0lKRcjTUxzPoeTkwFSbb5tbVxhbgAAAP//ADwAAAHdAsIQIgJ/dPUSAgBRAAAAAP//AB7/6QH4AuQQIgBDcAASAgBSAAAAAP//AB7/6QH4AuQQIgB2YgASAgBSAAAAAP//AB7/6QH4AtoQIgJpZPUSAgBSAAAAAP//AB7/6QH4AsQQIgJ/bvcSAgBSAAAAAP//AB7/6QH4AtkQIgBqYw0SAgBSAAAAAAADADIAAAIWAdgAAwAHAAsAPACyBgAAK7QHBAAdBCuwAi+0AwQANwQrsAovtAsEAB0EKwGwDC+wBtawCjK0BQUAOgQrsAgysQ0BKwAwMQEVITUFFSM1ExUjNQIW/hwBJmhoaAEPRkanaGgBcGhoAAAAAwAK/+ICCQIbABMAGwAjAHYAsgYAACuxFwTpsgoAACuyEAEAK7ATM7EfBOkBsCQvsA3WsSIF6bAiELEaASuxAwXpsSUBK7EiDRESsggJCzk5ObAaEbMGEBUdJBc5sAMSsgESEzk5OQCxFwYRErAIObAfEbUBCw0DFBwkFzmwEBKxABI5OTAxAQcWFRQGIyInByc3JjU0NjMyFzcHAxYzMjY1NAUTJiMiBhUUAgk/LH1vZzw9IEIwfm9lQTpc7is/RlD+6e8pRUZQAf9HSW2ElT5FHEpHc4SVQUGo/vMwbV9CtwENNG1fRAAAAP//ADz/6QHdAuQQIgBDZQASAgBYAAAAAP//ADz/6QHdAuQQIgB2cwASAgBYAAAAAP//ADz/6QHdAtkQIgJpafQSAgBYAAAAAP//ADz/6QHdAtkQIgBqaA0SAgBYAAAAAP//AAr/JgHUAuQQIgB2WQASAgBcAAAAAAACADz/JgIQAsoADgAZAGgAsgsAACuxFATpsgsUCiuzQAsACSuyBQEAK7EPBOmyBQ8KK7NABQEJKwGwGi+wANa0DgUAPAQrsQIRMjKwDhCxFwErsQgF6bEbASuxFw4RErEFCzk5ALEUCxESsA05sA8RsQgDOTkwMRcRMxU2MzIWFRQGIyInERMiBhQWMzI2NTQmPFM4aWZ6e2VhQJJCUFBCRFRT2gOk/1Ccgn2XTv7vAqdvuG9vWV5wAAAA//8ACv8mAdQC2RAiAGpWDRICAFwAAAAA//8ADwAAAosDZhAjAHEArACpEgIAJAAA//8AHv/pAgsCqRAiAHFu7BICAEQAAAAA//8ADwAAAosDhBAjAnsArACoEgIAJAAA//8AHv/pAgsC1xAiAntu+xICAEQAAAAAAAIAEf8zArQC2QAYABsAWgCyCwAAK7EGDjMzsgwDACuwAC+0FAQAEwQrtAkbCwwNK7EJBOkBsBwvsAPWtBIFABsEK7EdASuxEgMRErAHOQCxFAARErAXObALEbEDFjk5sQwbERKwGjkwMQUiJjU0NjcjJyEHIwEzASMOARUUMzI3FQYLAgJoOEwzLiBL/udNYwEEeAEAAjcnSCUaMMRweM00KiQ6EdvbAtn9Jx8sHzYKLQoB9gFM/rQAAAAAAgAe/zMCRwIbADQAPwFXALIfAAArtDUEAEMEK7AIMrILAAArshsAACuyAgEAK7ExBOmyMQIKK7NAMQAJK7AUL7QPBAATBCsBsEAvsCLWsT4F6bA+ELA0INYRsQAF6bAAL7E0BemwPhCxOAErsRguMjKxBgXptA0FABsEK7FBASuwNhq6DeTBhwAVKwoOsCYQsCnAsTwL+bA6wLoIA8CBABUrCg6wJxCwK8CxPDoIsTwM+bA6wLAmELMnJikTK7oJOcCrABUrC7AnELMoJysTK7EnKwiwJhCzKCYpEyuwJxCzKScrEyu6Ch3AzgAVKwuwPBCzOzw6EyuyOzw6IIogiiMGDhESOQC3KSsmJyg6OzwuLi4uLi4uLgG3KSsmJyg6OzwuLi4uLi4uLrBAGgGxODQRErMCHzE1JBc5sA0RsRsdOTkAsQ8UERKwEjmwHxGyDREYOTk5sTE1ERK0BQYdIjkkFzkwMRM2MzIWFREUMzI3FQYVFDMyNxUGIyIuATU0NjcmJwYjIiY1ND4ENzYzPgE9ATQjIgYHEzI2PQEOAxQWNgbLYWQtCQlMSCYaKh0eOjEfJTkGUWFPXRElKEA1KQYDMSV1OjsFUUVYGWVKPDYBcapJRv7MKQI/Hj03Ci0KECwhHSgUCkNNVEciMyIXDwkFAQYZGxZOLTD+wUkqXgwQDC1QLAAA//8AKP/pAp0DhBAnGFkBGAAAEgIAJgAA//8AHv/pAdwC5BAiAHZhABICAEYAAAAA//8AKP/pAp0DhBAnGFoA0gAAEgIAJgAA//8AHv/pAdwCxBAiAmlj3xACAEYAAAAA//8AKP/pAp0DhBAjAnwA2gC4EAIAJgAA//8AHv/pAdwC2RAiAnxcDRACAEYAAAAA//8AKP/pAp0DhBAnGFsA1gAAEgIAJgAA//8AHv/pAdwC3BAiAmpn9xICAEYAAAAA//8AUAAAApIDhBAnGFsArwAAEgIAJwAA//8AHv/pAtAC5BAnGF4CHAAAEAIARwAAAAIAFAAAApsC2QALABcAdACyCwAAK7ENBOmyBAMAK7EUBOm0AgELBA0rsAwztAIEACsEK7AVMgGwGC+wC9awAzKxDQXpsBQysg0LCiuzQA0XCSuyCw0KK7NACwEJK7ANELERASuxCAXpsRkBKwCxAQ0RErEIEDk5sRQCERKxBxE5OTAxEyM1MxEhMhYQBiMhExEzMjYQJisBFTMVWUVFARqKnp6K/uZdrWtwcGutqwFTQwFDwv6swwFT/v+QARaP8UMAAAACAB7/6QIxAtkAFgAhAJoAsgUAACuyCAAAK7EcBOmyFQMAK7IOAQArsRcE6bQTEhcVDSuwAjO0EwQAEwQrsAAyAbAiL7AL1rEaBemwGhCxHwErsRAUMjK0BAUAPAQrsAAysh8ECiuzQB8SCSuwBBC0BQUAGwQrsAUvsgQFCiuzQAQCCSuxIwErsR8aERKxDgg5OQCxHAURErAGObAXEbALObAOErAQOTAxATMVIxEjNQYjIiY1NDYzMhc1IzUzNTMDIgYUFjMyNjU0JgHyPz9KRmJmfHtlYUCWllPlRFRUREJQTwKNNf2oO1KdgnyXTos1TP7wbrJubFlcbf//AFAAAAJbA2YQIwBxALIAqRICACgAAP//AB7/6QH3AqkQIgBxcuwSAgBIAAAAAP//AFAAAAJbA4QQIwJ7ALEAqBACACgAAP//AB7/6QH3AtkQIgJ7cv0QAgBIAAAAAP//AFAAAAJbA4MQIwJ8ALAAtxICACgAAP//AB7/6QH3AtkQIgJ8cQ0SAgBIAAAAAAABAFD/MwKCAtkAHAB1ALIHAAArsBIzsRAE6bIIAwArsQsE6bAAL7QYBAATBCu0DA8HCA0rsQwE6QGwHS+wB9axEAXpsAsysBAQsQMBK7QWBQAbBCuyFgMKK7NAFhIJK7NAFgoJK7NAFg4JK7EeASsAsRgAERKwGzmwBxGxAxo5OTAxBSImNTQ2NyERIRUhFSEVIRUhFSMOARUUMzI3FQYCNjhMMy7+PQH5/mQBjf5zAa4CNydIJRowzTQqJDoRAtlS6VL6Uh8sHzYKLQoAAAAAAgAe/zQB9wIbACoAMACoALIbAAArsSgE6bIgAQArsS4E6bAOL7QJBAATBCu0MCMbIA0rtDAEACsEKwGwMS+wHtaxIwXpsDAysCMQsREBK7QGBQAbBCuwBhCxKwErsSIF6bEyASuxESMRErEbLjk5sAYRsxkgKC0kFzmwKxKzBAkOKiQXObAiEbILDAA5OTkAsQkOERKwDDmwGxGzBAsRFyQXObEjKBESsR0AOTmxLjARErAeOTAxJQ4EFRQWMzI3FQYjIiY1ND4EPwEGIyImEDYzMhEhHgMzMj8BNCYiBgcB7QcmKSgaJiImGikcP0wFCwoRCAgJKBxwf4Nt6f5+AR8wMRllJQVSflIEnylCLCgwHRgbCi0JMCgMFhIOEAYGBwiTAQSb/s80SyUQaY9EXFdJAP//AFAAAAJbA4QQJxhbALQAABICACgAAP//AB7/6QH3AtoQIgJqfPUSAgBIAAAAAP//ACj/6QLBA4QQJxhaAOYAABACACoAAP//AB7/JgHqAs8QIgJpdeoQAgBKAAAAAP//ACj/6QLBA4QQIwJ7AN4AqBICACoAAP//AB7/JgHqAtoQIgJ7Yf4SAgBKAAAAAP//ACj/6QLBA4QQIwJ8ANsAuBACACoAAP//AB7/JgHqAtkQIgJ8WA0QAgBKAAAAAP//ACj+1ALBAuUQJwLJAlIAABICACoAAP//AB7/JgHqAuoQIwK1AaUAABACAEoAAP//AFAAAAKBA4QQJxhaAMgAABACACsAAP//ADwAAAHcA4QQIwJpAIIAnxACAEsAAAACAB4AAAK0AtkAAwAXAHcAshQAACuwDzOyBQMAK7AJM7QBEhQFDSuxAQTptAcAFAUNK7ENFTMztAcEADcEK7EECzIyAbAYL7AV1rAEMrEBBemxBhIyMrIVAQors0AVFgkrsAEQsRABK7ECCDIysQ8F6bAKMrIPEAors0APDQkrsRkBKwAwMRMVITUlNTMVITUzFTMVIxEjESERIxEjNawBd/4sXQF3XTQ0Xf6KXjEB+FpaSJmZmZlG/gYBTP60AfpGAAAAAQAPAAAB7gLZABsAfwCyCAAAK7AaM7INAwArshYBACu0AwQAQwQrtAsKAw0NK7ARM7QLBAATBCuwDzIBsBwvsAjWsAwytAcFADwEK7EOEjIysgcICiuzQAcRCSuyCAcKK7NACAoJK7AHELEbASu0GgUAPAQrsR0BK7EbBxESsBY5ALEDCBESsBM5MDEBNCYjIgYVESMRIzUzNTMVMxUjFT4BMzIWFREjAZtDKUBOUz8/U5aWJUs4TFlTAWs3MGFQ/t8CWDVMTDWUMCdNQv50////+QAAATMDaRAjAn//9ACcEAIALAMA////5gAAASACuhAiAn/h7RACAPMUAAAA//8AAgAAARQDZhAjAHH/5gCpEgIALAAA////+gAAAQwCqRAmAPMUABACAHHe7AAA/////QAAASoDhBAjAnv/7gCoEAIALAMA////8QAAAR4C2RAiAnvi/RACAPMUAAAAAAEAGv8zAOoC2QATAEwAsggDACuwAC+0DwQAEwQrAbAUL7AD1rQNBQAbBCuwDRCxBwsrsQoF6bEVASuxCg0RErIABg85OTkAsQ8AERKwEjmwCBGxAxE5OTAxFyImNTQ2NyMRMxEOARUUMzI3FQaeOEwzLhdeNyhIJRowzTQqJDoRAtn9Jx8sHzYKLQoAAgAC/zMA0gLZABMAFwBeALIXAwArtBYEAB0EK7AAL7QPBAATBCsBsBgvsAPWtA0FABsEK7ANELEGASuwFjK0CQUAPAQrsBQysRkBK7EJBhESsgAKDzk5OQCxDwARErASObAWEbIDBxE5OTkwMRciJjU0NjcRMxEjDgEVFDMyNxUGExUjNYY4TC0oUwwwI0glGjAIVM00KiE4EQIL/fQcKh42Ci0KA6ZpaQAA//8AXwAAAMcDcxAjAnz/7ACnEgIALAAAAAEARgAAAJkCDAADACcAsgIAACuyAwEAKwGwBC+wAta0AQUAPAQrtAEFADwEK7EFASsAMDETESMRmVMCDP30AgwAAAD//wBk/+kCogLZECMALQDmAAAQAgAsAAD//wBC/yYBTQLZECMATQCiAAAQAgBMAAD//wAj/+kCEAOEECcYWgDdAAAQAgAtAAD////z/yYBEgLPECYB8BQAEAICad/qAAD//wBQ/tQCkwLZECcCyQI0AAASAgAuAAD//wA8/tQB+ALZECcCyQHwAAASAgBOAAAAAQA8AAAB+AIMAAoAMwCyCQAAK7AFM7IKAQArsAIzAbALL7AJ1rQIBQA8BCuwADKxDAErALEKCRESsQEHOTkwMRMVNzMJASMlFSMRj95r/vABMGf+/lMCDN7e/vz++NjYAgwA//8AUAAAAhUDhBAmGFluABICAC8AAAAA//8ADQAAAPIDhBAmGFkEABAGAE8AAAAA//8AUP7UAhUC2RAnAskCDAAAEgIALwAA//8APP7UAKYC2RAnAskBTwAAEgIATwAA//8AUAAAAhUC5BAnGF4BDgAAEAIALwAA//8APAAAAWgC5BAnGF4AtAAAEAIATwAA//8AUAAAAhUC2RAjAHkBUAAAEAIALwAA//8APAAAAU8C2RAjAHkAkAAAEAIATwAAAAEAHgAAAkYC2QANAE8AsgcAACuxBATpsgwDACuyAQEAKwGwDi+wB9awCzKxBAXpsAAysgQHCiuzQAQGCSuyBwQKK7NABwoJK7EPASsAsQEEERKzAAgJCyQXOTAxEzcVBxUhFSERBzU3ETPLq6sBe/4oUFBdAZZ5THr3UgEYOU04AXUAAAEAFAAAAOgC2QALADwAsgUAACuyCgMAKwGwDC+wBdawCTK0BAUAPAQrsAAysgQFCiuzQAQCCSuyBQQKK7NABQgJK7ENASsAMDETNxUHESMRBzU3ETOmQkJTPz9TAaUzQDP+mwE5MkAyAWAA//8AUAAAAooDhBAnGFkBGAAAEgIAMQAA//8APAAAAd0C5BAiAHZ9ABICAFEAAAAA//8AUP7UAooC2RAnAskCPgAAEgIAMQAA//8APP7UAd0CGxAnAskB8AAAEgIAUQAA//8AUAAAAooDhBAnGFsAxQAAEgIAMQAA//8APAAAAd0C2xAiAmp09hICAFEAAAAA//8AJwAAAksC2BAmAl/XFBACAFFuAAAAAAEAUP/wAn0C6AAkAGYAsgAAACu0CQQAQwQrsgUAACuwFTO0BgQANwQrshcDACuzExcbDiu0EQQAQwQrAbAlL7AW1rEVBemwGDKwFRCxDAErsSAF6bEmASuxDBURErIABRs5OTkAsREGERKyDBkgOTk5MDEFIi4CIzUyFjMyNjU0LgIjIgYVESMRMxU2MzIeAhUUDgIBfhUoFRUBA0IbP2wpQD4cRG1dXTqQKVZSNS1MVhAFBQZHDr2RTnQ7G2RN/hIC2U1cJUiBUnSxYzAAAAABADz/JgHdAhsAHABcALIUAAArshUBACuyGgEAK7QPBABDBCuwAy+0CAQAQwQrAbAdL7AU1rETBem0FwUAJgQrsBMQsQsBK7QBBQA8BCuxHgErsQsTERKyAwUaOTk5ALEPFBESsBc5MDEBERQjIic1FjMyNjURNCYjIgYVESMRMxU+ATMyFgHdjw0PEQMmHjoyQE5UTSNROkxaAYz+B20DRwEeJwG3LzhhUP7fAgxYNzBOAP//ACj/6QLoA2YQIwBxAOAAqRICADIAAP//AB7/6QH4AqkQIgBxauwSAgBSAAAAAP//ACj/6QLoA4QQIwJ7AOAAqBACADIAAP//AB7/6QH4AtkQIgJ7bP0QAgBSAAAAAP//ACj/6QLoA4QQJxhcAQ4AABICADIAAP//AB7/6QH4AuQQIwKAAJwAABICAFIAAAACACj/7AO8AuUAHAAtAJgAshQAACuxEQTpshcAACuxIwTpsgkDACuxDATpsCoysgYDACuxKATptA0QFwYNK7ENBOkBsC4vsADWsR0F6bAdELElASuxCBQyMrERBemwDDKyESUKK7NAERMJK7AKMrNAEQ8JK7EvASuxJR0RErEGFzk5ALERIxESsBU5sBARsCU5sA0SsQAdOTmwDBGwJjmwKBKwCDkwMRM0PgMzMhc1IRUhFSEVIRUhFSE1BiMiLgM3FB4DMzI3ESYjIg4DKCg9Uk0neT4Brf6wAUj+uAFV/k5DdShNUjwnXRopOTQdfTs7fB81OScaAWRYi1Q2FFhMUu5S9VJKXhQ1UYhaSW4/Jw14AWV4DidAbgAAAAMAHv/pA3kCGwAfACoAMQCdALIPAAArsAszsSYE6bAFMrImDwors0AmCAkrshoBACuwFTOxLwTpsCAytCsADxoNK7QrBAArBCsBsDIvsBLWsSMF6bAjELEpASuxAAXpsCsysAAQsSwBK7EfBemxMwErsSkjERKxFQ85ObAAEbENFzk5sCwSsgcLGjk5ObAfEbAIOQCxACYRErANObArEbISIyk5OTmwLxKwFzkwMSUeAzMyNzMOASMiJwYjIiY1NDYzMhc+ATMyFhcWFSQiBhUUFjMyNjU0FyE0JiMiBgH3AR4wMRpmI1QQdlmEPj+DcXx8cYc9H2U9SnEZFf3YjFBQRkVRWAEmUEA/Uuo0SyUQaVZgZ2eTh4aSajI4SkA3cORtXmBtbF5hM0dZVwAAAP//AFAAAAKaA4QQJxhZAQQAABICADUAAP//ADwAAAFLAuQQIgB2HgASAgBVAAAAAP//AFD+1AKaAtkQJwLJAkgAABICADUAAP//ADz+1AE4AhsQJwLJAVMAABICAFUAAP//AFAAAAKaA4QQJxhbAMEAABICADUAAP//AC0AAAFMAuUQIgJqGgASAgBVAAAAAP//ADD/6QJtA4QQJxhZAPoAABICADYAAP//ACL/6QHLAuQQIgB2VgASAgBWAAAAAP//ADD/6QJtA4QQJxhaAKoAABACADYAAP//ACL/6QHLAtAQIgJpVusQAgBWAAAAAAABADD/KgJtAuUASgDiALI/AAArsCMzsQAE6bINAwArsRQE6bIUDQors0AUEAkrsCwvtDQEABMEK7A5L7QmBAATBCsBsEsvsArWsRcF6bBDINYRsUYF6bAXELE3ASu0KQUAJgQrsCkQsQUBK7EeBemwESDWEbEQBemxTAErsDYauu/UwhQAFSsKDrAIELAHwLEaCfmwG8AAswcIGhsuLi4uAbMHCBobLi4uLrBAGgGxF0YRErBBObA3EUAJAA0UIyQmLC5AJBc5ALE0LBESsC45sDkRsykvOzwkFzmxAD8RErBBObAUEbIKHkQ5OTkwMSUyPgI1NC8BJjU0NjMyFhcjLgEjIgYVFBYfAR4BFRQOAg8BNjMyFhUUBiMiJzceAzMyNjU0IyIHJzcmIycuAT0BMxUUHgIBVjhOJQ+GtY+LeH6MAVgBXldKWTZCt0pRGDt3VA8ODiYpQjkvThUHHxIcDhcfLg4RCx8JAixZZ1gTK1U7GiopF1MjMCWFY3N3a0dNRDcqMBIxFGBDKEVEKwQgAiMgKzIiKAMPCAcaEyUHBkUDBxOAWwcFHzY0HwAAAAABACL/KgHLAhsAQADxALIQAQArsRUE6bIVEAors0AVEgkrsC0vtDUEABMEK7A6L7QnBAATBCsBsEEvsA3WsRgF6bAYELAAINYRsUAF6bBAL7EABemwGBCxOAErtCoFACYEK7AqELEGASuxHwXpsB8QsBIg1hGxEwXpsBMvsRIF6bFCASuwNhq68NrB0QAVKwoOsAoQsAnAsRsE+bAcwACzCQobHC4uLi4BswkKGxwuLi4usEAaAbEADRESsS8wOTmxOBgREkAKAw8VJCUnLTI9PiQXObETKhESsBA5ALE1LRESsC85sDoRsyowPD0kFzmxFScRErINJD45OTkwMTceATMyNjU0Ji8BLgE1NDYyFhcjJiMiBhUUFh8BHgEVFAYHBg8BNjMyFhUUBiMiJzceAzMyNjU0IyIHJzcmJ3oGNUU3QyYrTl1JbrZiAVgDZjM8LjNQTkY0LiZPDg4OJilCOS9OFQcfEhwOFx8uDhELH6gDnC83LSUdIgoTFkM+SVdUTVQrJBwjDBMTRTovThQRBSACIyArMiIoAw8IBxoTJQcGRxGgAAD//wAw/+kCbQOEECcYWwCoAAASAgA2AAD//wAi/+kBywLdECICalT4EgIAVgAAAAAAAQAe/ysCWgLZACIAhQCyEgMAK7ERBOmwFDKwIC+0BQQAEwQrsAovtBoEABMEKwGwIy+wD9axFgXpshYPCiuzQBYUCSuyDxYKK7NADxEJK7MIFg8IK7QdBQAmBCuxJAErsQgPERK2BQwOFxgaICQXOQCxBSARErAiObAKEbMADA0dJBc5sREaERKyDhYXOTk5MDEXHgMzMjY1NCMiByc3IxEjNSEVIxEjBzYzMhYVFAYjIifFCSERGg0XHy4PEAwqIPACPO8XFw0PJilCOS9OiwQQBwYaEyUIB1sCh1JS/Xk3AiMgKzIiAAEAFP8dASsCnAAvALsAsiIAACu0IQQANwQrsg4AACuyFAEAK7AYM7QTBAArBCuwGjKyFBMKK7NAFBcJK7AtL7QFBAATBCuwCi+0JwQAEwQrAbAwL7AR1rAVMrQcBQA8BCuwFzKyHBEKK7NAHBoJK7AhMrIRHAors0AREwkrsBwQsQgBK7QqBQAmBCuxMQErsRwRERK0AgUMDg0kFzmwCBG1Ch8kJSctJBc5ALEFLRESsC85sAoRswAMDSokFzmxISIRErAfOTAxFx4DMzI2NTQjIgcnNy4BNREjNTM1MxUzFSMRFBYzMjcVBg8BNjMyFhUUBiMiJ0gJIREaDRcfLg8QDCYoKkdHU1ZWExsZDxwVEw0PJilCOS9OmQQQBwYaEyUIB1MEKiQBjESQkET+mRwTBEYFAS8CIyArMiIAAAD//wAeAAACWgOEECcYWwCQAAASAgA3AAD//wAU/+kBmgLkECcYXgDmAAAQAgBXAAAAAQAeAAACWgLZAA8AYACyDgAAK7IFAwArsQQE6bAHMrQBAA4FDSuwCzO0AQQANwQrsAkyAbAQL7AO1rACMrENBemwCDKyDQ4KK7NADQsJK7NADQcJK7IODQors0AOAAkrs0AOBAkrsREBKwAwMRM1MzUjNSEVIxUzFSMRIxGBjfACPO+NjV0BZUjaUlLaSP6bAWUAAAEAFP/pAQkCnAAdAIQAsg8AACu0CgQAQwQrshkBACuwADO0GAQAKwQrsAEyshkYCiuzQBkcCSu0FBUPHA0rsAMztBQEADcEK7AFMgGwHi+wEtaxFhoyMrQHBQA8BCuxAhwyMrIHEgors0AHAQkrsAwys0AHBQkrshIHCiuzQBIYCSuxHwErALEUChESsAw5MDEBFSMVMxUjFRQWMzI3FQYjIiY9ASM1MzUjNTM1MxUBCVZPTxMbGQ8nHTE0TExHR1MCDESQSI8cEwRGBysotEiQRJCQAAAA//8AUP/pAoADaRAjAn8AywCcEAIAOAAA//8APP/pAd0CvxAiAn9w8hACAFgAAAAA//8AUP/pAoADZhAjAHEAyACpEgIAOAAA//8APP/pAd0CqRAiAHFs7BICAFgAAAAA//8AUP/pAoADhBAjAnsAyACoEAIAOAAA//8APP/pAd0C1xAiAnts+xACAFgAAAAA//8AUP/pAoADxRAjAn0AxgDBEgIAOAAA//8APP/pAd0DBBAiAn1qABICAFgAAAAA//8AUP/pAoADhBAnGFwA5gAAEgIAOAAA//8APP/pAd0C2xAjAoAAhP/3EgIAWAAAAAEAUP8zAoAC2QAjAHsAsggAACuxEQTpsgwDACuwFTOwAC+0HwQAEwQrAbAkL7AL1rEOBemwDhCxAwErtB0FABsEK7AdELEUASuxFwXpsSUBK7EDDhESsQgROTmwHRGwBjmwFBKyABsfOTk5sBcRsSEiOTkAsR8AERKwIjmwCBGyAxshOTk5MDEFIiY1NDY3BiMiJjURMxEUFjMyNjURMxEUDgMVFDMyNxUGAgo5TCInOSyDll1lVVhkXSU0NCVIJRowzTQpHy8YDYBwAgD+AE9PVEoCAP4ANFc5MDQbNgotCgAAAAEAPP80AgQCDAAkAKAAshcAACu0IAQAQwQrsgEAACuyEwAAK7IbAQArsAAzsA0vtAcEABMEKwGwJS+wGta0HQUAPAQrsB0QsSMBK7QBBQA8BCuzBAEjCCu0EAUAGwQrsBAvtAQFABsEK7ABELQTBQAmBCuwEy+xJgErsRAdERKxFyA5ObEBBBESsgcNEjk5OQCxBw0RErAKObAXEbIECRA5OTmxGyARErAUOTAxAREOARUUFjMyNxUOASMiJjU0NyM1DgEjIiY1ETMRFBYzMjY1EQHdIyokHxcaBScIPkpgFiVQOkxbUzoyQU4CDP30FDsdGBwKLQEIMis+MUk0LE5BAZT+jS84YVABKf//AA8AAAOaA4QQJxhaATYAABACADoAAP//AAoAAALIAtEQIwJpAML/7BACAFoAAP//AA8AAAKXA4QQJxhaAKwAABACADwAAP//AAr/JgHUAs8QIgJpVuoQAgBcAAAAAP//AA8AAAKXA3EQIwBqAK4ApRICADwAAP//AB4AAAJJA4QQJxhZAPAAABICAD0AAP//AB4AAAHIAuQQIgB2XwASAgBdAAAAAP//AB4AAAJJA3EQIwJ8AJgApRICAD0AAP//AB4AAAHIAtkQIgJ8UA0SAgBdAAAAAP//AB4AAAJJA4QQJxhbAJwAABICAD0AAP//AB4AAAHIAt0QIgJqWPgSAgBdAAAAAAABABQAAAEEAtwAEABBALIBAAArsgkDACu0DgQAQwQrsgQBACu0AwQAKwQrAbARL7AB1rAFMrQABQA8BCuyAQAKK7NAAQMJK7ESASsAMDEzIxEjNTM1NDYzMhcVJiMiFa1TRkZBOhcYEwo6AchEWTg/BUUBNQAAAAACABT/6QInAtkAFgAhAJQAshMAACuyDwAAK7EdBOmyAQMAK7IJAQArsRcE6bQWFRcBDSuwBTO0FgQAEwQrsAMyAbAiL7AT1rAAMrQaBQA8BCuxAgYyMrQSBQAbBCuyEhMKK7NAEgUJK7ITEgors0ATFQkrsBoQsSABK7EMBemxIwErsSAaERKxCQ85OQCxHRMRErARObAXEbAMObAJErAHOTAxEzUzFTMVIxU2MzIWFRQGIyInFSMRIzUFIgYVFBYzMjY0JlNTlpZAYWV7fGZiRko/ASRDT1BCRFRUAo1MTDWLTpd8gp1SOwJYNcRtXFlsbrJuAAAAAAMAKAAAAyIC2QAJAA8AMACIALIkAAArsQkE6bIVAwArsQ0E6bAlMrIrAQArsRAE6bQOCCQrDSuxDgTpAbAxL7AS1rEoBemwKBCxJAErsQkF6bANMrAJELEEASuxIAXpsAsg1hGxGwXpsTIBK7EkKBESsRAuOTmxCwkRErAdOQCxCAkRErAgObAOEbAdObENKxESsRIbOTkwMSUyPgE1NCYrARUANCsBFTMlIjU0NjMhMh4CFRQHHgEVFAYjIREjIhUUFjMyNjMVBgJCMT4URD/jAUaStLT+kHs9RwF+PVotFGVGP3Zh/rdSMRsbAhALGFIrNB45RfsBTejoIZoxTiQ7Ox9wLxtUQl5yAoI6Fx4BTwUA//8AUAAAAnAC2RACA4UAAAACADz/6QIRAtkACgAbAG8AsgsAACuyGAAAK7EFBOmyDAMAK7QPBABDBCuyEgEAK7EABOkBsBwvsAzWtBAFADwEK7ACMrQbBQAmBCuyGwwKK7NAGw4JK7AQELEIASuxFQXpsR0BK7EIEBESsRIYOTkAsQAFERKyEBUaOTk5MDEBIgYUFjMyNjU0JgERIRUhFTYzMhYVFAYjIicVASFCUFBCRFVT/tUBh/7MOWloeHxoazsBzW+4b29ZXnD+MwLZSctWlH+CnVpDAAIAAQAAAqEC2QAIABYASgCyFAAAK7EABOmyCQMAK7QLCBQJDSuxCwTpAbAXL7AU1rEABemwCjKwABCxBAErsRAF6bEYASuxABQRErAJOQCxCwgRErAVOTAxNzMyNjU0JisBAzMRMzIWHQEUBiMhESfe1EBSUUHUXV2lloiCZP7GgFJSPUBQAWj+6nhmA2N/AcOLAAACAAH/6QIzAtkACgAbAG4AshkAACuyFQAAK7EFBOmyCwMAK7IPAQArsQAE6QGwHC+wGta0AwUAPAQrsAwytBgFACYEK7ADELEIASuxEgXpsR0BK7EYGhESsAs5sQgDERKxDxU5OQCxAAURErMNEhcaJBc5sQsPERKwGzkwMQEiBhQWMzI2NTQmATMRNjMyFhUUBiMiJxUjEScBQ0JQUEJEVVP+1VM5aWh4fGhrO0tdAc1vuG9vWV5wAQz+7FaUf4KdWkMBw4sA//8AKP/pAp0C5RALACYCxQLOwAAAAQAo/+kC5QLlACgAfgCyIwAAK7EdBOmyHSMKK7NAHSAJK7IGAwArsRcE6bAKINYRsQ8E6bIPCgors0APEwkrAbApL7AA1rEaBemwGhCxIAErsSEF6bAUINYRsRMF6bEqASuxFBoRErIGHSM5OTmxEyARErAIOQCxDx0RErEAGjk5sQoXERKwCDkwMRM0PgMzMhc2MzIXFSYjIgYdASMuASMiBhUUFjMyNjczAiEiLgMoETBHeUyKSB9QFxgTCh4cXxBeV2p7gG1aYBFgIf71S3dHLxEBZDJiak80TzsFTwEYHVJOTqKMiaFlav7fM05pYAAAAAEAHv/pAi0CLAAiAH0AshsAACuxFQTpshUbCiuzQBUYCSuyIQEAK7EPBOmyDyEKK7NADwsJK7AhELACINYRtAcEAEMEKwGwIy+wHtaxEgXpsBIQsQwBK7AXMrELBemwGDKxJAErsQwSERKyFRshOTk5sAsRsAA5ALEPFRESsB45sSEHERKwADkwMQE2MzIXFSYjIgYdASMuASMiBhUUFjMyNzMOASMiJjU0NjMyAZMZUhcYEwoeHFQIQDRETU5FaxVUCHBea31/alQB7j4FRQEYHVI3O29iXWp+YGuVf4KcAAAA//8AFAAAApsC2RACAJIAAAACACgAAANEAtkACAAhAGgAshUAACuxAATpsg4DACuxCATpsBYyshwBACuxCQTpshEBACsBsCIvsAvWsRkF6bAZELEVASuxAAXpsAAQsQQBK7ESBemxIwErsRUZERKxCR85OQCxCQARErEEEjk5sQgcERKwCzkwMSUzMjY1NCYrAQciNTQ2MyEyFhAGIyERIyIVFBYzMjYzFQYBX6xscHBsrLx7PUcBb4uen4r+51IxGxsCEAsYUpCKi5DHmjFOwv6swwKCOhceAU8FAAACACgAAAJIAtkADgAaAEkAsgoAACuxFATpsgcDACuxBgTptAMXCgcNK7EDBOkBsBsvsADWsRAF6bAQELEVASuwBDKxCQXpshUJCiuzQBUGCSuxHAErADAxNzU0ITM1ITUhESEiLgI2FB4COwERIyIOASgBD7T+dAHp/rc9WS0UXQsZOCfj4yc4GdoC19RS/ScrRUY6LiktGgEPGywAAAAAAgAe/+kB8wLZAAoAGwB1ALIMAAArsg8AACuxBgTpshoDACu0GQQAQwQrshUBACuxAATpAbAcL7AS1rEDBemwAxCxFwErsAgytBsFADwEK7IXGwors0AXGQkrsBsQtAwFACYEK7AML7EdASuxFwMRErEPFTk5ALEABhESsg0SFzk5OTAxASIGFRQWMzI2NCYTIzUGIyImNTQ2MzIXNSE1IQEORlNVREJQUKNLO2tofHhoaTn+zAGHAc1wXllvb7hv/jNDWp2Cf5RWy0n//wAe/zsCCgIkEAsDRwIoAhTAAAABAB4AAAIpAtkACwBKALIJAAArsQoE6bIGAwArsQUE6bQCAQkGDSuxAgTpAbAML7AL1rADMrEIBemyCwgKK7NACwEJK7NACwUJK7NACwkJK7ENASsAMDEBITUhNSE1IREhNSEBzP5zAY3+ZAH5/fUBrgFMUulS/SdSAAD//wAo/+kCngLlEAIESgAAAAEAKP/pAmUC5QAvAIYAsgAAACuxJATpsiQACiuzQCQrCSuyDAMAK7ETBOmyEwwKK7NAEw8JK7QZHAAMDSuxGQTpAbAwL7AF1rEfBemwCSDWEbEWBemwHxCxKQErsSsF6bAQINYRsQ8F6bExASuxEBYRErUADAcaGyQkFzkAsRwkERKwBTmwGRGwBzmwExKwCTkwMQUiLgI1NDcmNTQ2MzIWFyMuASMiBhUUFjsBFSMiBhUUHgIzMj4CPQEzDgMBRVF2PBqCaYt4fowBWAFeV0pZXz9YbENgDyVOODtVKxNYATZZXBcrR0cmfTEtbGNzd2tHTUQ3LltSVC4WKSsaHjQ3HwVKaTUXAAEAAv8mAkMC2QASAD4AsgEDACuxBATpsAwvsREE6bAIL7EFBOkBsBMvsADWsQkF6bAEMrIJAAors0AJAwkrs0AJBwkrsRQBKwAwMRcRIRUhFSEVIREUBiMiJzUWMzJaAen+dAFc/qRRSA0PEQNETAMlUulS/kc1OANRAQABAAD/JgECAtwAHQBdALIVAwArtBoEAEMEK7IQAQArsAAztA8EACsEK7ABMrAFL7QKBABDBCsBsB4vsA3WsBEytAMFADwEK7AcMrIDDQors0ADAQkrsBcysg0DCiuzQA0PCSuxHwErADAxARUjERQjIic1FjMyNjURIzUzNTQ2MzIXFSYjIh0BAQJXjw0PEQMmHkZGQToXGBMKOgIMRP3LbQNHAR4nAhREWTg/BUUBNVIAAAABACj/6QMOAuUALgCuALIPAAArshIAACuxBgTpshsDACuxLATpsB8g1hGxJATpsiQfCiuzQCQoCSu0CwwSGw0rsQsE6QGwLy+wFdaxAAXpsAAQsQkBK7QNBQA8BCuyCQ0KK7NACQsJK7ANELAoINYRsSkF6bApL7EoBemwDRC0DwUAEQQrsA8vsTABK7EpABESsgYSGzk5ObAJEbEQHTk5ALELBhESsBA5sAwRsQAVOTmxLCQRErAdOTAxExQeAzMyNj0BIzUhESMnBiMiJjU0PgMzMhc2MzIXFSYjIgYdASMuASMiBoUOJDlePGSB3gEwOxdokZS6EjJLf1CSVBxXFxgTCh4cXw9xU3SMAWomTVQ/KX5iFFL+e2F01KgwYWpQNVJDBU8BGB1SRlGjAAAAAgAP/+UClwLZAAgAGgBTALINAwArsBAzsBcvtAAEADYEKwGwGy+wCdaxBgXpsAYQsQIBK7EUBemxHAErsQYJERKwDDmwAhGxDxc5ObAUErASOQCxDQARErMECQ8UJBc5MDElMjU0JwYVFBYnNDY3ATMbATMBFhUUBiMiLgEBWB0cIBNxGDX+53PW0G/+7k1IMiw9FEMkIzg7IBISIx8+WwG7/p0BY/5FZ0k+SzU3AAABADz/6QM3AtkAKwB8ALINAAArsgEAACu0GQQAQwQrsg4DACuyEwEAK7QIBABDBCsBsCwvsA3WtAwFADwEK7APMrAMELEEASu0FwUAPAQrsBcQsR8BK7EmBemxLQErsQQMERKwEzmxHxcRErEiIzk5ALEIGREStAQQFh8mJBc5sBMRsSIjOTkwMQUjIiY1ETQmIyIGFREjETMRPgEzMhYVERQzMj4DNTQmJzceARUUDgMCJTcxNEMpQE5TUyVLOExZSS1GJhgINUhmMT8OJztkFysoAS83MGFQ/t8C2f7rMCdNQv7VLyMxPSsQLnQzBCZ9OxM8UEIvAAEAQv/pAOsC2QANAC8AsgkAACu0BAQAQwQrsg0DACsBsA4vsAzWtAEFADwEK7EPASsAsQ0EERKwBjkwMRMRFBYzMjcVBiMiJjURlRMbGQ8nHTE0Atn9iBwTBEYHKygCnQAAAAABAA8AAAFcAtkACwBNALILAAArsgQDACu0AgELBA0rsAgztAIEACsEK7AGMgGwDC+wC9awAzKxCgXpsAUysgoLCiuzQAoICSuyCwoKK7NACwEJK7ENASsAMDETIzUzETMRMxUjESOGd3deeHheAVNDAUP+vUP+rQABAFAAAAKhAtkAEwA+ALICAAArsBEzsgMDACuwCCDWEbENBOkBsBQvsALWsQEF6bAEMrEVASsAsQ0CERKyBQsTOTk5sAgRsAo5MDETFSMRMxEBNjMyFwcmIyIPAQEjAa1dXQEgQT00IjgKECAfqQEsbv7/AP//Atn+jwEnPR8+Ch+q/lABdgAAAQA8AAAB+ALcABQAPACyAAAAK7AQM7IEAwArtAkEAEMEK7INAQArAbAVL7AA1rQUBQA8BCuwCzKxFgErALENABESsQwSOTkwMTMRNDYzMhcVJiMiFRE3MwcTIwMHFTxBOhcYEwo63mu21mexUQJlOD8FRQE1/tDetf6pARxQzAABAAYAAAFTAtkACwBNALILAAArsgQDACu0AgELBA0rsAgztAIEACsEK7AGMgGwDC+wC9awAzKxCgXpsAUysgoLCiuzQAoICSuyCwoKK7NACwEJK7ENASsAMDETIzUzETMRMxUjESOCfHxUfX1UAVNDAUP+vUP+rQABAAr/9gIYAuIAIgBDALIPAAArsQkE6bIAAwArsAQzsR8E6QGwIy+xJAErALEJDxESsg0VFjk5ObAfEbYGAwwUFxkgJBc5sAASsQUhOTkwMRMyFhc3FQcTFjMyNjcXBiMiLgEnCwEjEycHNTI3LgEjBzc2cCo6HohvuwgUBRoDFDAhGSEOCXqSYMYGqAWLECUZNgohAtwkNV9MTf4TEwgDRhgYGxsBYv5cAggSdE1iHRIIUgwAAAAAAQBQ//EDEALZACAAdgCyAQAAK7IKAAArsAUzsRME6bAbMrIOAwArsRcfMzMBsCEvsA3WsRAF6bAQELEWASuxGQXpsBkQsR4BK7EABemwABC0AQUAPAQrsAEvsSIBK7EWEBESsAo5sBkRsAc5sB4SsAU5ALETARESsAc5sA4RsAI5MDEhIzUOASMiJw4BIyImNREzERQWMzI2NREzERQzMjY1ETMDEFMiSzRhLCVINEpUXy8tM0NfWzNDX0ovKlAsJExGAlb91TI3TzoCC/3VaU86AgsAAAAAAf/4/yYCigLZABIARgCyBwAAK7IBAwArsAQzsAwvsREE6QGwEy+wANaxCQXpsAkQsQMBK7EGBemxFAErsQMJERKxAgc5OQCxAQcRErEDCDk5MDEXETMBETMRIwERFAYjIic1FjMyUGUBfVhp/odNRw0PEQNETAMl/awCVP0nAk/9RDU4A0wBAAEAPP84Ad0CGwATAE4AshMAACuyAAEAK7IFAQArtA4EAEMEKwGwFC+wE9axEgXptAIFACYEK7ASELEKASu0CQUAPAQrsRUBK7EKEhESsAU5ALEOExESsAI5MDETMxU+ATMyFhURIxE0JiMiBhURIzxNI1E6TFpTOjJATlQCDFg3ME5B/awCMy84YVD+3wAAAAMAKP/pAugC5QAKABEAFwBlALIDAAArsRYE6bIIAwArsQ4E6bQTEQMIDSu0EwQANwQrAbAYL7AG1rETBemwETKwExCxEgErsAsysQAF6bEZASuxEhMRErMIDBADJBc5ALETFhESsAU5sBERsAA5sA4SsAY5MDEBFAYjIiYQNjMyFgcuASMiBgcFIR4BMjYC6MCgnsLCnaDBXgiLcG2NBwID/f4Mi9SMAWGi1tMBVtPUkH2VlnxGdYuMAAAAAgAo/+kDFgMcAAkAIgBtALINAAArsQUE6bISAwArsQAE6QGwIy+wENaxAwXpsAMQsQcBK7EKBemzGgoHCCuxHwXpsSQBK7EHAxESsg0SFjk5ObAaEbEcITk5sR8KERKwHTkAsQAFERKzCg8QISQXObASEbIWGh85OTkwMQEiBhAWMjY1NCYTFAYjIiYQNjMyHgEzMj4BNTQnNxYVFAcWAYd0jo/oj47rwKCewsKdPmxCDBkYEhFAJWs9ApOl/vKlpISKpv7OotbTAVbTJCQDDQ4XFDYrOF0QYQAAAAIAHv/pAi8CdwAKACEAcwCyFAAAK7EFBOmyGQEAK7EABOmyDQEAK7IfAQArAbAiL7AX1rEDBemwAxCxCAErsREF6bMfEQgIK7ENBemxIwErsQgDERKyFBkcOTk5sB8RsQ8hOTmxDRERErALOQCxAAURErMPERYXJBc5sBkRsBw5MDEBIgYUFjMyNjU0JjcWFRQHFhUUBiMiJhA2MzIWMzI2NTQnAQtGUFBGRVFPuCVcJX9ucH1+bjhSDR8bEQHObb5tbVxhbqkrOFYURWeBlJUBCJUjDBIXFAAAAAACACj/6QOoAuYACQAjAHYAshsAACuyDQAAK7EFBOmyEgMAK7AWM7EABOmxHwTpAbAkL7AQ1rEDBemwAxCxBwErsQoF6bAKELEbASuxGgXpsSUBK7EHAxESsg0SFDk5ObAKEbAiObAbErEWHzk5ALEABRESswoPECIkFzmxEh8RErAUOTAxASIGEBYyNjU0JhMUBiMiJhA2MzIXNjMyFhURIxE0JiMiBgcWAYd0jo/oj47rwKCewsKdcVZPZVRSXigmKCoaWAKTpf7ypaSEiqb+zqLW0wFW0zg5ZlH90QJNGzQSGGkAAAAAAgAe/zgCmgIbAAoAIwCEALIYAAArsQUE6bIdAQArsCEzsQAE6bIdAQArtBEEACsEK7IAHQors0AADQkrAbAkL7Ab1rEDBemwAxCxCAErsRUF6bAVELENASuxDAXpsSUBK7EIAxESshgdHzk5ObAVEbATObANErERITk5ALEABRESsxMVGhskFzmxHRERErAfOTAxASIGFBYzMjY1NCYFESMRNCYjIgcWFRQGIyImEDYzMhc2MzIWAQtGUFBGRVFPAUhUFiInIzR/bnB9fm5UOEA+RkABzm2+bW1cYW5d/ccCTScqE0l8gZSVAQiVKSlJAAAAAAIAKAAAAxAC2QAHACMAbQCyDgAAK7IgAwArsQcE6bAPMrIVAQArsRsE6bQADA4VDSuxAATpAbAkL7Ad1rESBemwEhCxDwErsQAF6bAMMrAAELEEASuxCAXpsSUBK7EPEhESsRgbOTkAsRUbERKxAwg5ObAHEbEEHTk5MDEBMzI2NCYrAQUUBisBESMRIyIVFBYzMjYzFQYjIjU0NjMhMhYBX8JDS0tDwgGxcVvlXVIxGxsCEAsYF3s9RwGDbHUBh0R4RIRdcf7LAoI6Fx4BTwWaMU5vAAAAAAIAPP8mAhEC3AAKACIAZACyFAAAK7EFBOmyHAMAK7QhBABDBCuyDgEAK7EABOkBsCMvsBjWsRcF6bACMrQMBQAmBCuwFxCxCAErsREF6bEkASuxCBcRErQOFBweISQXOQCxBRQRErAWObAAEbEMETk5MDEBIgYUFjMyNjU0JicVNjMyFhUUBiMiJxEjETQ2MzIXFSYjIgEiQlBQQkRUU947bGh5e2VhQFQ+ORUYEwo6Ac1vuG9vWV5wkaFemoR9l07+7wM/OT4FRQEAAAIAUP+DAnsC2QAHAB8AeACyCgAAK7IbAAArsgsDACuyBwEAK7ENBOm0CAAKDQ0rsQgE6QGwIC+wCtaxCQXpsQAMMjKwCRCxGwErsAMysRUF6bERBemyERsKK7NAERcJK7EhASuxFRsRErETGTk5ALEIChESsRUcOTmwABGwEzmwBxKwETkwMRMzMjY0JisBERUjETMVMzIWFRQHFhUUFxUjJj0BNCYjrcJBSUlBwl1d0Gh4VkkrcRQ7PQEPRHhE/q69Atl4cWN0OiuQbxsXLklBQz8AAQAw/+kCbQLlADAAtACyDQAAK7EABOmyAA0KK7NAAAcJK7IkAwArsR0E6bIdJAors0AdIQkrAbAxL7AT1rEsBemwLBCwICDWEbEhBemwIS+xIAXpsCwQsRoBK7EnBemwJxCwByDWEbEFBemwBS+xBwXpsTIBK7A2GroQs8I3ABUrCg6wFhCwF8CxKgn5sCnAALMWFykqLi4uLgGzFhcpKi4uLi6wQBoBsRogERKyAA0kOTk5ALEdABESsRMnOTkwMSUyPgI9ATMOBCMiLgM1NDY/AT4BNTQmIyIGByM+ATMyFhUUDwEGFRQeAgFHO1UrE1gBJThOSylBZz4oD1FKt0I2WUpXXgFYAYx+eIuPtYYPJU47HzQ2HwU8XDcjDR4uPTkdQ2AUMRIwKjdETUdrd3NjhSUwI1MXKSoaAAEAIv/pAcsCGwAkALsAsgMAACuxIgTpsiIDCiuzQCIBCSuyFgEAK7EQBOmyEBYKK7NAEBMJKwGwJS+wBtaxHwXpsBMg1hGxEgXpsB8QsQ0BK7EYBemwACDWEbEBBemxJgErsDYaug7KwbsAFSsKDrAJELAKwLEcBPmwG8C6EgfClwAVKwqxCQoIsAkQsArAsRwE+bAbwACzCQobHC4uLi4BswkKGxwuLi4usEAaAbENEhESswMVFiIkFzkAsRAiERKxBhg5OTAxJTMGIyImNTQ2PwE+ATU0JiMiByM+ATIWFRQGDwEOARUUFjMyNgFzWAbLY3VGTlAzLjwzZgNYAWK2bkldTismQzdFNJyzWkw6RRMTDCMcJCtUTVRXST5DFhMKIh0lLTcAAQAeAAACSQLZAAsALACyCgAAK7EHBOmyAgMAK7EFBOkBsAwvsQ0BKwCxBwoRErALObAFEbABOTAxEwM1IRUhEwMhFSE1+dkCDf5m29sBtv3VAW0BGFRS/ub+5VJSAAAAAgAA/yYBTwLcAAoAIAB2ALISAwArtAAEAB8EK7AeL7QZBABDBCuwDS+0BgQAHwQrAbAhL7AQ1rQDBQAbBCuwAxCxIAErtBYFADwEK7AWELQIBQAbBCuwCC+xIgErsSADERKzAAYNEiQXOQCxDRkRErAWObAGEbALObAAErIPEBU5OTkwMRMiBhUUFjI2NTQmFwYjIiY0NjMyFhURFBYzMjcVBiMiNXsZJSUyJSQOEhYySUkyOUIfJgMRDw2QAp4kGBkkJBgaI7AHSWRIRDj9VCceAUcDbQAAAQAU/yYBBAKcAB4AZwCyBgEAK7AKM7QFBAArBCuwDDKwFi+0GwQAQwQrAbAfL7AD1rEHGDIytA4FADwEK7AJMrIDDgors0ADBQkrsA4QsR4LK7EUBemwCzKxIAErsQ4DERKxFhs5OQCxBRsRErEREzk5MDEXLgE1ESM1MzUzFTMVIxEUFjMyNxUUIyInNRYzMjY1sCksR0dTVlYTGxkPkA0PEQMmHhYDKyQBjESQkET+mRwTBKNtA0cBHicAAAAAAQAPAAACYALZABUAXgCyCQAAK7IEAwArsQwE6bAGMrIPAQArsRQE6QGwFi+wANaxDgXpsg4ACiuzQA4SCSuwDhCxCQErsQgF6bIICQors0AIBgkrsRcBK7EJDhESsBQ5ALEMDxESsAA5MDETND4BNyEVIxEjESsBIhQzMjcVBiMiDxM/MgHN710rUjE2ChMYF3sCWh80KwFS/XkCh3QBTwUAAAABABT/6QEFAtwAHgBpALINAAArtAgEAEMEK7IYAwArtB0EAEMEK7ITAQArsAEztBIEACsEK7ADMgGwHy+wENawFDK0BQUAPAQrsAAysgUQCiuzQAUDCSuxChoyMrIQBQors0AQEgkrsSABKwCxEggRErAKOTAxExUzFSMRFBYzMjcVBiMiJjURIzUzNTQ2MzIXFSYjIq5WVhMbGQ8nHTE0R0dBOhcYEwo6Al5SRP6ZHBMERgcrKAGMRFk4PwVFAQABAB7/JgJaAtkAEAA8ALIDAwArsQIE6bAFMrAOL7EJBOkBsBEvsADWsQcF6bIHAAors0AHBQkrsgAHCiuzQAACCSuxEgErADAxBREjNSEVIxEUMzI3FQYjIiYBDvACPO9EAxEPDUhRbQL0UlL9LTsBUQM4AAEAUP/pAwMDWAAbAFQAsggAACuxEQTpshYDACuwDDOxBATpAbAcL7AL1rEOBemwDhCxFAErsQUF6bAFELEZASuxAgXpsR0BK7EUDhESsAg5sRkFERKwGzmwAhGwADkAMDEBFhUUBxEUBiMiJjURMxEUFjMyNjURMz4BNTQnAt4lg5mAgpVdZVVYZF0YFxEDWCs4Zgn+U26CgW8CAP4AT09USgIAAQsSFxQAAAABADz/6QJqAosAHQB3ALIGAAArsgoAACu0EwQAQwQrshgBACuwDjOxBATpAbAeL7AN1rQQBQA8BCuwEBCxFgErtAQFADwEK7AEELQGBQAmBCuwBi+wBBCxGwErsQIF6bEfASuxFhARErAKObEbBBESsB05sAIRsAA5ALEEExESsAc5MDEBFhUUBxEjNQ4BIyImNREzERQWMzI2NREzPgE1NCcCRSWNSyVQOkxbUzoyQU5dGBcRAosrOGsF/khJNCxOQQGU/o0vOGFQASkBCxIXFAAA//8AKP/8As0C2RALAzwC9QLZwAAAAQBQ/+kCjwLZAB4AQwCyAAAAK7ENBOmyBgMAK7AZMwGwHy+wBdaxCAXpsAgQsRMBK7EcBemxIAErsRMIERKyABkaOTk5ALEGDRESsBw5MDEFIi4CNREzERQeAjMyPgM9ATQuAiczFhUUBgFJN01NKF0YKCgWJ0dGMyAVNCkrbI6zFw8sYUoCCv3OIC0WCQ8nPWE/AjhjaURBvsGvwgAAAAEADwAAAskC2QAYAD4AsgoAACuyEQMAK7AMM7ECBOkBsBkvsArWsQkF6bEaASuxCQoRErAOOQCxAgoRErIACw45OTmwERGwGDkwMQEmIyIOAgcDESMRATMbATYzMh4EFwKkFRkLFgsRAbNd/udz1q0tQQoUDRAIEAMCaRUQDx4B/t7+4gEeAbv+nQEjQAMECQUKAgABAAr/JgJgAtwAGwBsALIUAwArtBkEAEMEK7INAQArsA4zsgABACuwAy+xCATpAbAcL7EdASuwNhq6wzLsCAAVKwqwDS4OsAzABbEOCvkOsA/AALEMDy4uAbMMDQ4PLi4uLrBAGgEAsQgDERKwBTmwDRGxAQY5OTAxAQMGIyInNRYzMjY/AQMzGwE+AjMyFxUmIyIGAdTpKF8fGRsRGh8KILFZhpEfOzUmGxYWBSYuAgz9hmwNSwYXHFUCDP5oAZhXXRwFRQE3AAEAHgAAAkkC2QARAEIAsgkAACuxBgTpshEDACuxEATptA0MCRENK7AEM7QNBAArBCuwAjIBsBIvsRMBKwCxBgkRErAKObEQDRESsAE5MDEBFQczFSMDIRUhNRMjNTM3ITUCR7lNgccBtv3Vx1eLu/5mAtlU70P+/1JSAQFD8VIAAQAeAAAByAIMABEASACyCQAAK7QGBABDBCuyEQEAK7QQBABDBCu0DQwJEQ0rsAQztA0EACsEK7ACMgGwEi+xEwErALEMBhESsAo5sRANERKwATkwMQEVBzMVIwchFSE1NyM1MzchNQG6e1OKhQFF/laEXZV9/twCDEqVQ6FJS59DlkkAAQAo/+kCTQLZAB4AbACyEAAAK7EVBOmyFRAKK7NAFRIJK7IDAwArsQIE6bQbGhADDSuxGwTpAbAfL7AS1rETBemwExCxGAErsQ0F6bIYDQors0AYAgkrsSABK7EYExESswEQBhokFzkAsRsaERKwBjmwAhGwBTkwMQE3ITUhFQceBB0BDgEjIiczFjMyNjU0IzUyPgEBTY3+ZgINtB4sMR8VAZt8+BBYCapRau0VHg0B0rVSVOgHECArRiwDZHnll01BnksLDAABAB7/6QJDAtkAHwBxALIPAAArsQoE6bIKDwors0AKDAkrshwDACuxHwTptAQFDxwNK7EEBOkBsCAvsBLWsQcF6bIHEgors0AHBQkrs0AHHgkrsAcQsQwBK7ENBemxIQErsQwHERKyDxofOTk5ALEEBRESsBo5sB8RsBs5MDEBHgIzFSIVFBYzMjczBiMiJic0NTQ+AzcnNSEVIQEeDA0eFe1qUaoJWBD4fJsBFR8xLB60Ag3+ZgHSDQwLS55BTZfleWQBAixGKyAQB+hUUgAAAQAe/3EB+AIMABgAbQCyAgEAK7QFBABDBCuwEy+xDQTpsg0TCiuzQA0QCSsBsBkvsBbWsQoF6bIKFgors0AKBwkrsAoQsRABK7ERBemxGgErsQoWERKxAgE5ObAQEbIFABM5OTmwERKxBAM5OQCxBQ0RErEBFjk5MDETJzUhFSEXFSMiFRQWMzI2NzMGIyImNTQ22I8Bh/7cjzCTTkVISAVYENptg2EBFK5KSatLgENLSk3leGVYYwAAAAABAB7/NgHfAgwAKQCiALInAQArtCYEAEMEK7AUL7QNBABDBCuwBS+0HAQAQwQrsBwQsBkg1hG0CAQANwQrAbAqL7AX1rQKBQAmBCuwChCxHwErtAIFACYEK7IfAgors0AfIwkrsSsBK7EKFxESsSYnOTmwHxG1BQANFBklJBc5sAISsw8QKCkkFzkAsQ0UERKwEDmwBRGwDzmwCBKxChc5ObEmGRESsgIfKTk5OTAxARYVFAYjIiYjIhUUFjMyNxcGBwYjIiY1NDMyFjMyNjU0JisBNTchNSEVASi3f2EUVw4ZPTZXYhddQhgZYWFgHVwIMGFTSDCP/twBhwEUFZNQYhEQHCAmRSIGAkxCTxA0MCs7S6tJSgAAAQAiAAAB/wLFAB8AaACyEQAAK7EOBOmyAgIAK7EdBOmyHQIKK7NAHQAJKwGwIC+wANaxHwXpsB8QsRoBK7EFBemxIQErsR8AERKyDhUWOTk5sBoRtAIKBxcUJBc5sAUSswgJDxAkFzkAsR0OERKxBRQ5OTAxEzYzMhYVFAcXFScHDgEHIRUhPgE3JzUXNzY1NCYjIgcyB+NlfoJXpyhBOAcBdf4oBklfU6EnYFA8hQoBz/Z0XHtPJE1EFSNCLVdvfDkiTUIWN1U5TKkAAQAe/+sBzgKcACMAkQCyAwAAK7QKBAA3BCuyCgMKK7NACgYJK7IWAQArsBoztBUEACsEK7AcMgGwJC+wBta0BwUAJgQrsAcQsRMBK7AXMrQeBQA8BCuwGTKyHhMKK7NAHhwJK7ITHgors0ATFQkrsB4QsQ0BK7QABQA8BCuxJQErsR4TERKxAwo5ObANEbEQITk5ALEVChESsAA5MDElFAYjIiY1MxQWMzI2NTQuAz0BIzUzNTMVMxUjFRQeAwHOeF1oc08/SD9IJjY2JkdHU1ZWJjY2JqtdY3xuRF44Oik1HR89Lh5EkJBEFh8tIiZEAAAAAAIAPP8mAhMCHAAKAB4APgCyDgEAK7ITAQArsQkE6QGwHy+wDdaxDAXpsAAytBAFACYEK7AMELEGASuxFgXpsSABK7EGDBESsBM5ADAxExE+AzU0JiMiAxUjETMVPgEzMhYVFA4EBwaQLlNpQDcqaGFUSzxoT0JXJUZHYTsnCgFo/p4eQWV4Oikp/fObAuZQOiZeTjFhU0RCJhYG//8AX/8sAJsC2RACAF8AAP//AF//LAEJAtkQIgBfbgAQAgBfAAAAAAABADL/LAIWAtkAEwBsALIAAwArsA0vsAgztA4EADcEK7AGMrINDgors0ANCwkrsBEvsAQztBIEADcEK7ACMgGwFC+wC9axAA8yMrQKBQAbBCuxAQUyMrIKCwors0AKCAkrsAMysgsKCiuzQAsNCSuwETKxFQErADAxATMRMxUjFTMVIxEjESM1MzUjNTMBBDzW1tbWPNLS0tIC2f6IRmZG/r0BQ0ZmRv//AHwAAADQAtkQAgAEAAD//wBQAAAE3QOEECMBPwKUAAAQAgAnAAD//wBQAAAEeALdECMBQAKwAAAQAgAnAAD//wAe/+kD6gLdECMBQAIiAAAQAgBHAAD//wBQ/+kDygLZECMALQIOAAAQAgAvAAD//wBQ/yYC1wLZECMATQIsAAAQAgAvAAD//wA8/yYBdQLZECMATQDKAAAQAgBPAAD//wBQ/+kEbALZECMALQKwAAAQAgAxAAD//wBQ/yYDaQLZECMATQK+AAAQAgAxAAD//wA8/yYCwwLZECMATQIYAAAQAgBRAAD//wAPAAACiwOEECcYWwCqAAAQAgAkAAD//wAe/+kCCwLZECICanD0EAIARAAAAAD//wAHAAABJgOEECYYW/MAEAIALAMAAAD////zAAABEgLZECICauD0EAIA8xQAAAD//wAo/+kC6AOEECcYWwDgAAAQAgAyAAD//wAe/+kB+ALZECICam70EAIAUgAAAAD//wBQ/+kCgAOEECcYWwDKAAAQAgA4AAD//wA8/+kB3QLZECICam/0EAIAWAAAAAD//wBQ/+kCgAPFECMAagDEAJQQIwBxAMMBCBICADgAAP//ADz/6QHdAzUQIgBqbuUSIgBYAAAQAgBxbXj//wBQ/+kCgAPeECcYWQEiAFoQIwBqAMoAfxICADgAAP//ADz/6QHdA4QQIgBqbu8SIgBYAAAQAwB2AJgAoAAA//8AUP/pAoAD1BAnGFsAyABQECMAagDKAHASAgA4AAD//wA8/+kB3QOEECIAam7lEiIAWAAAEAMCagBwAJ8AAP//AFD/6QKAA9QQJxhYALoAUBAjAGoAygB/EgIAOAAA//8APP/pAd0DhBAiAGpu5RIiAFgAABADAEMASQCgAAD//wAe/+kB9wIbEAsASAIVAgTAAP//AA8AAAKLA8UQIwBqALAAlBAjAHEArwEIEgIAJAAA//8AHv/pAgsDIBAiAGpw4xIiAEQAABACAHFxY///AA8AAAKLA7gQIwJ8AKoAixIiACQAABADAHEArAD7//8AHv/pAgsDIBAiAnxs4xAiAEQAABACAHFuY///AA8AAAO6A2cQIwBxAcgAqhACAIgAAP//AB7/6QNJAr0QIwBxARIAABACAKgAAAABACj/6QL2AuUALQDFALIYAAArshsAACuxBgTpsiQDACuxKwTpsiskCiuzQCsoCSu0CgsbJA0rsBMztAoEAB8EK7AVMrQQERskDSuxEATpAbAuL7Ae1rEABemwABCxDgErtBMFADwEK7AWMrITDgors0ATFQkrsg4TCiuzQA4KCSuwEDKwExCwJyDWEbEoBemwKC+wCTOxJwXpsBMQtBgFABEEK7AYL7EvASuxKAARErIGGyQ5OTmwDhGwGTkAsQoGERKwGTmxERARErEAHjk5MDETFB4DMzI2NyM1MzY9ASM1IRUzFSMVIycGIyImNTQ+AzMyFhcjLgEjIgaFDiQ5XjxGbhvI2gTeATA1NTsXaJGUuhIyS39QfaETXw9xU3SMAWomTVQ/KUI5OhMYFFKROrphdNSoMGFqUDV6b0ZRowAAAAACAB7/JgIDAhsACwAvAKsAshkAACuxBgTpsiIBACuyHwEAK7EABOmwLC+0DgQANwQrsBEvsCgztBIEABMEK7AmMgGwMC+wHNaxAwXpsAMQsAwg1hGxLwXpsC8vsQwF6bADELEVASuwCTKxJAXpsCQQtCEFACYEK7AhL7IkIQors0AkKAkrsTEBK7EVDBEStAAGGR8sJBc5sSQhERKxJik5OQCxEhERErEMLzk5sQAGERKyFhwhOTk5MDEBIgYVFBYzMjY1NCYDFjMyNyM1MzY9AQ4BIyImNTQ2MzIXNTMRFAczFSMOASMiJicBBkNOTkRCTEvGDnFHJmN+CiNLMVx8e2RiPk0LJDUXa0xcbgcBzm5eX21rXmJt/fZYKDQkQBsyLJd9gJ5bTP5KWzM0NjhUSgAA//8AKP/pAsEDhBAnGFsA3AAAEAIAKgAA//8AHv8mAeoC2RAiAmpa9BACAEoAAAAA//8AUAAAApMDhBAnGFsAywAAEAIALgAA//8APAAAAfgDhBAjAmoAZgCfEAIATgAAAAIAKP8jAugC5QAcACYAaQCyDAMAK7EdBOmwAC+0GAQAEwQrAbAnL7AJ1rEgBemwIBCxAwErtBYFABsEK7AWELEkASuxDwXpsSgBK7EWAxESsCE5sCQRtgAMEwYaHSIkFzkAsRgAERKwGzmwHRG0AwkPGiEkFzkwMQUiJjU0NjcuATU0NjMyFhUUDgEHDgEVFDMyNxUGAyIGEBYyNjU0JgGIOEwtKYunwp2gwU6WZDAjSCUaMB10jo/oj47dNCoiNxIPzp6r09SwZaZnBRwqHjYKLQoDcKX+8qWkhIqmAAAAAgAe/yMB+AIbABsAJgBjALIMAQArsRwE6bAAL7QXBAATBCsBsCcvsAnWsR8F6bAfELEDASu0FQUAGwQrsBUQsSQBK7EPBemxKAErsSQVERK2AAwSBhkcISQXOQCxFwARErAaObAcEbQDCQ8ZISQXOTAxBSImNTQ2Ny4BNTQ2MzIWFRQGBw4BFRQzMjcVBgMiBhQWMzI2NTQmAQs4TC4qXGV+bnF9cWQwI0glGjAcRlBQRkVRT900KiI4EQ+RdoSVlYh5kwgcKh42Ci0KAqttvm1tXGFuAAD//wAo/yMC6ANmECMAcQDgAKkQAgGqAAD//wAe/yMB+AKJECIAcWvMEAIBqwAAAAD//wAo/+kCTQOEECcYWwCbAAASAgF5AAD//wAU/3EB7gLZECICal/0EgICNQAAAAD////f/yYA/gLKECYB8AAAEAICaszlAAD//wBQAAAE8wLZECMAPQKqAAAQAgAnAAD//wBQAAAEfALZECMAXQK0AAAQAgAnAAD//wAe/+kD9ALZECMAXQIsAAAQAgBHAAD//wAo/+kCwQOEECcYWQFAAAAQAgAqAAD//wAe/yYB6gLXECMAdgCC//MQAgBKAAAAAgBQAAACOQLnAA4AIQBLALIRAAArsAwvsRcE6QGwIi+wEdaxEAXpsQATMjKwEBCxCQErsRoF6bEjASuxCRARErAXOQCxDBERErIBFBo5OTmwFxGxEhM5OTAxExE+BjU0JiMiBgMVIxEzFT4BMzIWFRQOBa8jGE8nPyAaPiMpazVfXz1fTkJeIy5TOGQiAiv+uhcPOSRBNkYiISov/iGEAtdQOyVeTixbRVAuQhMAAP//AFAAAAKKA4QQJxhYAOYAABACADEAAP//ADwAAAHdAuQQIgBDbgAQAgBRAAAAAP//AA8AAAKLA4QQJxhZAMgAABAjAn0AqAAMEkIAJAAAQAAwAP//AB7/6QILA4QQJxhZAKoAABACAKcAAP//AA8AAAO6A4QQJxhZAhwAABACAIgAAP//AB7/6QNJAtcQIwB2AT3/8xACAKgAAP//ACP/6QLtA4QQJxhZAUAAABACAJoAAP//AAr/4gIJAtcQIwB2AJf/8xACALoAAP//AA8AAAKLA4QQJhhdbgAQAgAkAAAAAP//AB7/6QILAtkQIwKyAdH/9RACAEQAAP//AA8AAAKLA4QQIwK0AfYAqBACACQAAP//AB7/6QILAsoQIwK0AbX/7hACAEQAAP//AFAAAAJbA4QQJxhdAIwAABACACgAAP//AB7/6QH3AtkQIwKyAd7/9RACAEgAAP//AFAAAAJbA4QQIwK0AfsAqBACACgAAP//AB7/6QH3AsoQIwK0Ab//7hACAEgAAP///98AAAEsA4QQJhhd3wAQAgAsAAAAAP///7kAAAEGAtkQIwKyAVf/9RACAPMUAP////8AAAEsA4QQIwK0AT0AqBACACwDAP///+0AAAEaAsoQIwK0ASv/7hACAPMUAP//ACj/6QLoA4QQJxhdALQAABACADIAAP//AB7/6QH4AtkQIwKyAcn/9RACAFIAAP//ACj/6QLoA4QQIwK0Ai0AqBACADIAAP//AB7/6QH4AsoQIwK0Abr/7hACAFIAAP//AFAAAAKaA4QQJhhdeAAQAgA1AAAAAP///+sAAAE4AtkQIwKyAYn/9RACAFUAAP//AFAAAAKaA4QQIwK0AgYAqBACADUAAP//AC0AAAFaAsoQIwK0AWv/7hICAFUAAP//AFD/6QKAA4QQJxhdAIwAABACADgAAP//ADz/6QHdAtkQIwKyAfL/9RACAFgAAP//AFD/6QKAA4QQIwK0AhUAqBACADgAAP//ADz/6QHdAsoQIwK0Abn/7hACAFgAAP//ADD+1AJtAuUQJwLJAioAABAGADYAAP//ACL+1AHLAhsQJwLJAdAAABAGAFYAAP//AB7+1AJaAtkQJwLJAgwAABAGADcAAP//ABT+1AEEApwQJwLJAWwAABAGAFcAAAABACj/nAHzAsUAKQBVALIGAgArsQAE6bIABgors0AABAkrAbAqL7AE1rEDBemwAxCxJwErsQkF6bAbINYRsQ4F6bErASuxAwQRErEUFzk5sCcRsgYgIzk5ObAbErAMOQAwMQEiBgcjNjMyFhUUBgcWFRQOAwcGByc+AjU0LgInBgcnNjc2NTQmAQdMOQJYBdllczEcYjA7g1BYEQgWPqOKCx4RGEBbFHslTEMCeFNF5WhbMU8QMXsvTzM6GxwFA1cQQlwkHykbCQsiHEsyGDA8OEEAAAEAFP+sAYACHgAoAGEAsAAvsQcE6bIABwors0AABAkrAbApL7AE1rEDBemwAxCxJwErsQoF6bAKELAPINYRsR0F6bAdL7EPBemxKgErsQMEERKyFhcZOTk5sCcRsgcgIzk5ObEKHRESsA05ADAxEyIGFSM0NjMyFhUUBgcWFRQOBAcnPgQ1NCYnBgcnNjc2NTTGJzVWYk9MYCIVRhc1Mlw6OBELI1pFORIdLkoRYRssAdA4MFBmWEQoOgwjXR80LB8kFBJKAwkgIjUbHx8TGRZFJxQgKVEA//8AUAAAAoEDhBAnGFsAyAAAEAIAKwAA//8APAAAAdwDhBAjAmoAhgCfEAIASwAAAAEAUP8lAoAC5QASAEQAsgEAACuyAgMAK7IGAwArsQ8E6QGwEy+wAdaxAAXpsAMysAAQsQsBK7EKBemxFAErsQsAERKwBjkAsQIPERKwBDkwMTMjETMVNjMyFhURIxE0JiMiBhWtXV1KcoKVXWVVWGQC2Sg0gW/9MALQT09USgAAAQAe/ygCSQLZABQASwCyEAAAK7ECBOmyFAMAK7ETBOmwBi+0CwQAQwQrAbAVL7AO1rEEBemwADKyDgQKK7NADhAJK7EWASsAsQIQERKwETmwExGwATkwMQEVASEVFCMiJzUWMzI2PQEhNQEhNQJH/kwBtpANDxEDJh7+KQG2/mYC2VT9zb1tA0cBHidKUgI1UgAAAAEAHv8oAcgCDAAUAFQAsgEAACu0CAQAQwQrsgUBACu0BAQAQwQrsAwvtBEEAEMEKwGwFS+wFNaxCgXpshQKCiuzQBQBCSuxFgErsQoUERKxBwY5OQCxBAgRErECBzk5MDEpATUBITUhFQEhFRQjIic1FjMyNjUBdP6qATn+3AGH/skBRZANDxEDJh5LAXhJSv6HtG0DRwEeJwAA//8ADwAAAosDhBAjAnwAqgC4EAIAJAAA//8AHv/pAgsC2RAiAnxsDRACAEQAAAAAAAEAUP8xAlsC2QAmAJIAsg8AACuwGjOxGATpshADACuxEwTpsCQvtAUEABMEK7AKL7QeBAATBCu0FBcPEA0rsRQE6QGwJy+wD9axGAXpsBMyshgPCiuzQBgaCSuzQBgSCSuzQBgWCSuwGBCxCAErtCEFACYEK7EoASuxCBgRErYNDhscHiQmJBc5ALEFJBESsCY5sAoRswAMDSEkFzkwMRceAzMyNjU0IyIHJzcjESEVIRUhFSEVIRUjBzYzMhYVFAYjIifaCSERGg0XHy4PEAwn8AH5/mQBjf5zAa71FA0PJilCOS9OhQQQBwYaEyUIB1UC2VLpUvpSMQIjICsyIgACAB7/GgH3AhsALwA4AJkAshQBACuxNgTpsC0vtAUEABMEK7AKL7QnBAATBCuwGi+0MAQAKwQrAbA5L7AR1rEaBemwMDKwGhCxCAErtCoFACYEK7AqELEzASuxGQXpsToBK7EIGhESQAoNDhQeJCUnLS82JBc5sTMqERKxIDE5ObAZEbAhOQCxBS0RErAvObAKEbMADA0qJBc5sRonERKyDw4kOTk5MDEXHgMzMjY1NCMiByc3LgE1NDYzMhYXFhUhFhcWMzI3Mw4BDwE2MzIWFRQGIyInAyE2NTQmIyIGkAkhERoNFx8uDxAMJ2Vzg21KcRkV/n4BGytTZiNUD21UFA0PJilCOS9OBAEmAVQ9P1KcBBAHBhoTJQgHVgeUeoGbSkA3cEgoRGlSXwUxAiMgKzIiAfICBEFZVwD//wAo/+kC6APFECMAagDiAJQSIgAyAAAQAwBxAOIBCP//AB7/6QH4AyAQIgBqbdsSIgBSAAAQAgBxcWP//wAo/+kC6APmECMAcQDnASkQAgCXAAD//wAe/+kB+AMgECICf27ZEiIAUgAAEAIAcXJj//8AKP/pAugDhBAjAnwA3gC4EAIAMgAA//8AHv/pAfgCvRAiAnxp8RACAFIAAAAA//8AKP/pAugD2RAjAnwA3gCkECIAMgAAEAMAcQDgARz//wAe/+kB+AMiECICfGnjECIAUgAAEAIAcWtl//8ADwAAApcDUxAjAHEArACWEAIAPAAA//8ACv8mAdQCiRAiAHFUzBACAFwAAAAAAAH/7v8mAJkCDAAMACUAsgABACuwBC+0CQQAQwQrAbANL7AM1rQCBQA8BCuxDgErADAxEzMRFCMiJzUWMzI2NUZTjw0PEQMmHgIM/YdtA0cBHicAAAMAHv/pA3UC2QALABYAMQCUALImAAArsioAACuwIjOxBgTpsA8yshgDACuyMAEAK7AcM7EABOmwFTIBsDIvsC3WsQMF6bADELEJASuwFzK0GgUAPAQrsAwysyUaCQgrtCYFABsEK7AmL7QlBQAbBCuwGhCxEgErsR8F6bEzASuxCQMRErEqMDk5sRIaERKxHCI5OQCxAAYRErUXGh8kJy0kFzkwMQEiBhUUFjMyNjU0JhYUFjMyNjU0JiMiBxEzETYzMhYVFAYjIicVIzUOASMiJjU0NjMyAQ1EVFRFQlBQo1BCRFVTRkKjUzlpaHh8aGs7QiJPNmp6e2ZsAc1wW1xvblteb2+4b29ZXnADAQ/+7FaUf4KdWkNFMSuZhX2XAAMAHv8mA3QCGwALABYALwCfALItAAArsBozsQ8E6bAGMrItDwors0AtGAkrsiMBACuyIAEAK7AnM7EABOmwFTIBsDAvsB3WsQMF6bADELEYASuwCTKxFwXpsAwysyUXGAgrtCIFABsEK7AiL7QlBQAbBCuwFxCxEgErsSoF6bExASuxGAMRErMABhsgJBc5sRIXERKxJy05OQCxDy0RErAvObAAEbQZHSIlKiQXOTAxASIGFRQWMzI2NTQmFhQWMzI2NTQmIyIDIxEGIiY1NDYzMhc1MxU2MzIWFRQGIyInAQ5FVFRFQlBPolBCRFRTRUJQVDnQeHxoazxDO2xoeXtlYUABzXBbXG9uWl5wb7hvb1lecP1ZARZTlH+CnVVGT16ahH2XTgD//wAU/+kCAQIbEAsARAIfAgTAAAACAB7/6QIoAhoACwAjAGoAsgwAACuxCQTpsh4AACu0GQQANwQrshUBACuyEgEAK7QDBAArBCsBsCQvsA/WsQYF6bAGELEUASuwADK0FgUAPAQrsSUBK7EUBhESsQwSOTmwFhGwITkAsQkZERKwITmwAxGxDxQ5OTAxATQmIyIGFRQWMzI2ByImNTQ2MzIXNTMRFDMyNxUGIyImJw4BAZFPRj9IVUNARKRLhHBsWkJTLQkJIxYoKwUmSgEHV3l/U1F4d8GadnqeUEL+TCkCPwklKyQi//8AFP/yAh4CIxALAfQCPAIMwAAAAgA8/+kCEQLcAAoAIgBnALILAAArsh8AACuxBQTpsg8DACu0FAQAQwQrshkBACuxAATpAbAjL7AM1rQXBQA8BCuwAjK0IgUAJgQrsBcQsQgBK7EcBemxJAErsQgXERKzDxEZHyQXOQCxAAURErIXHCE5OTkwMQEiBhQWMzI2NTQmARE0NjMyFxUmIyIdATYzMhYVFAYjIicVASFCUFBCRFVT/tVBOhcYEwo6OWloeHxoazsBzW+4b29ZXnD+MwJlOD8FRQE1mVaUf4KdWkMA//8AHv/pAdwCGxALAEYB+gIEwAAAAgAL/9YB1wIbAAoALQCLALIOAAArsQAE6bIZAQArsSAE6bIgGQors0AgHQkrtAcpDhkNK7EHBOkBsC4vsBbWsSMF6bAjELEDASuwHTK0CwUAJgQrsRwF6bEvASuxIxYRErESFDk5sAMRtQAOEBkJKSQXObALErAbOQCxAA4RErEQEzk5sAcRsgsUJTk5ObEgKRESsRYjOTkwMSUyNjUuAiMiBxY3FAYjIicGByc3JjU0NjMyFhcjLgEjIgYVFBc2NzYzMh4CAQg4RAIGGRctXR3xW21OODAXMEQwf2pbbQdUCEA0RE0bVxYeKRgrLRs2GhYREg1NEywwSSkqEjw2SWyCnGJdNztvYk4wSAwRCho3AAAAAgAe/yYCUALZAAsAJABoALIPAAArsQYE6bIYAwArshUBACuxAATpsCIvtB0EAEMEKwGwJS+wEtaxAwXpsAMQsQkBK7AXMrQaBQA8BCuwGhC0JAUAGwQrsCQvsSYBK7EJAxESsQ8VOTkAsQAGERKyDBIXOTk5MDEBIgYVFBYzMjY1NCYTDgEjIiY1NDYzMhcRMxEUFjMyNxUGIyI1AQ1EVFRFQlBQWSJPNmp6e2ZsNVMiJwMRDw2LAc1wW1xvblteb/54MSuZhX2XUQEP/NsmHwFHA20AAAAAAgAe/+kCSgLcAAsAJABqALIOAAArshIAACuxBgTpsh4DACu0IwQAQwQrshgBACuxAATpAbAlL7AV1rEDBemwAxCxCQErsBoytA0FADwEK7ANELQOBQAbBCuwDi+xJgErsQkDERKxEhg5OQCxAAYRErIPFRo5OTkwMQEiBhUUFjMyNjU0JjcRIzUOASMiJjU0NjMyFzU0NjMyFxUmIyIBDURUVEVCUFCjSiJPNmp6e2ZsNUE6FxgTCjoBzXBbXG9uW15vkf2iRTErmYV9l1GbOD8FRQEAAAAAAgAe/+kB9wIbABIAGQBuALIHAAArsQ0E6bINBwors0ANCgkrsgIBACuxFgTptBkABwINK7QZBAArBCsBsBovsADWsRkF6bAZELESASuwEzKxBQXpsRsBK7EZABESsAo5sBIRsgILBzk5OQCxAA0RErAFObEWGRESsAQ5MDE3EjMyFhAGIyImJzMWMzI+AjcnLgEjIgYHHgTlbYOAblp2EFQjZhcuMyEBAgVSPzxTAuoBMZv+/pVgVmkOI0w3RElXWUcA//8AHv/pAfcCGxALAEgCFQIEwAAAAgAe/+kC/AI6AAYANwCcALIwAAArsQQE6bIUAQArsQ4E6bIOFAors0AOEQkrshQOCiuzQBQYCSu0AQcwGA0rtAEEACsEK7ABELAoINYRsRwE6QGwOC+wN9axAQXpsAEQsQABK7AIMrEtBemxOQErsQE3ERKwETmwABGzDhAUMCQXObAtErEWKzk5ALEHKBESsSYtOTmxDhwRErIaJSs5OTmwFBGxFio5OTAxJSEUFjMyNiUhLgQjIgcjPgEzMhc3Mx4CMzI+BjcVBiMiAwcWFRQGIyIuBQGe/tlZOD9S/oUBggEYISwjEWYjVBB2WmQ/WUULJyAPBw4KDAcMBA0CLSpPPUUjg20wTDAjEAkB1k1TV40tRCUXB2lWYD5dHIxUBAULBxEHFQNyLQECR0JegZsaJj0wRyIAAQAe/+kBxwIbACMAoQCyAwAAK7EhBOmyIQMKK7NAIQEJK7INAQArsRIE6bISDQors0ASDwkrtBgbAw0NK7EYBOkBsCQvsArWsRUF6bIVCgors0AVGgkrsBUQsB4g1hGxBgXpsAYvsR4F6bAVELEQASuxDwXpsAAg1hGxAQXpsSUBK7EeChESsAg5sRAVERKzDA0DISQXOQCxGyERErAGObAYEbAIObASErAKOTAxJTMGIyImNTQ3JjU0NjIWFyMmIyIGFRQWOwEVIyIGFRQWMzI2AW9YBstjdVZBbrZiAVgDZjM8MTA+Sis7QDZFNJyzWkxWJiVLSVdUTVQrJCE1TDYfJS03AAD//wAe/+kBxwIbEAIDqwAAAAEAHv/pAswCOgA+AMoAsjwAACuxAwTpsgM8CiuzQAM+CSuyGAEAK7ESBOmyEhgKK7NAEhUJK7IYEgors0AYHAkrtAoLPBwNK7EKBOmwChCwKiDWEbEgBOkBsD8vsD7WsQAF6bAVINYRsRQF6bAAELEPASuxNQXpsg81CiuzQA8KCSuwDxCwBiDWEbE5BemxQAErsQ8UERKyAxg8OTk5sTUGERKyGjM3OTk5ALEKAxESsDk5sQsqERKxKDc5ObESIBEStA8eJzM1JBc5sBgRshovMTk5OTAxNx4BMzI2NTQmKwE1MzI2NTQmIyIHIz4BMzIXNzMeAjMyPgQ3FQYjIi4CJyYnFAcWFRQHFhUUBiMiJ3YGNUU2QDsrSj4wMTwzZgNYAWJbYDdVRQooIRAKEQsQBhECLSoZKiIWDwEBPgdBVnVjywacLzctJR82TDUhJCtUTVQwTxuNVAcHFAkcBHItKFNFOgUDAj4XGkslJlZMWrMAAAIAHv/pAdwCGwATACgAfwCyDwAAK7EaBOmyAwEAK7EUBOm0IiEPAw0rsSIE6QGwKS+wEtaxFwXpsBcQsSYBK7EGBemyJgYKK7NAJiEJK7AmELAdINYRsQwF6bEqASuxJhcRErMPFBoDJBc5sQYdERKwCTkAsSEaERKwDDmwIhGyCRIXOTk5sBQSsAY5MDETPgEzMhYVFAYHHgEVFAYjIiY1NDciBhUUFjMyNjU0JisBNTMyNjU0Jh4BYXpccB8iLCpyY3lv30c/R082PTsrNSkwMT8BDoiFV0koNRMUOy1MWoSdAsJZc21fLSUfNkw1ISQrAAABABT/JgEMAgwAFABRALIAAQArsAgvtA0EAEMEK7ASL7AEM7QTBAA3BCuwAjIBsBUvsBDWsAAytAYFADwEK7ABMrIGEAors0AGBAkrshAGCiuzQBASCSuxFgErADAxEzMVMxUjERQjIic1FjMyNjURIzUzbFNNTY8NDxEDJh5OTgIM1Ej+o20DRwEeJwE8SAACAB7/JgJBAooACwAyAJIAshMAACuxBgTpshkBACuxAATpsicBACuwLS+0DAQANwQrsgwtCiuzQAwwCSuwJC+0HwQAQwQrAbAzL7AW1rEDBemwAxCwMSDWEbEwBemwMC+xMQXpsAMQsQ8BK7AJMrEoBemwKBC0GwUAJgQrsBsvsTQBK7EPMREStAAGExktJBc5ALEABhESsxAWGygkFzkwMQEiBhUUFjMyNjU0JgMyNj0BDgEjIiY1NDYzMhc1NDYzMhcVJiMiBhURFA4CIyImJzMWAQZDTk5EQkxLR1Q+I0sxXHx7ZGI+PDkXGBMKHhwSMF9JXG4HVQ4Bzm5eX21rXmJt/Z5eYhsyLJd9gJ5bUzk+BUUBGB3+SktlVipUSlgAAAAAAgAe/yYCHgIbAAsALwCRALIMAAArsQYE6bISAQArsQAE6bIXAQArsRsE6bAjL7QpBAA3BCuyKSMKK7NAKSYJKwGwMC+wD9axAwXpsAMQsCcg1hGxJgXpsCYvsScF6bADELEsASuwCTKxHgXpsTEBK7EsJxEStAAGDBIjJBc5sB4RsRQWOTkAsRsGERK1AwkPFB4tJBc5sRcAERKwGDkwMQEiBhUUFjMyNjU0JgMiJjU0NjMyFz4BMhcHJiMiFREUDgIjIiYnMxYzMjY9AQ4BAQZDTk5EQkxLVFx8e2RiPAMkPh4OCgYWEjBfSVxuB1UOcVQ+I0sBzm5eX21rXmJt/huXfYCeWSMuC0gDJf64S2VWKlRKWF9hGzIsAAABAB7/6QIKAhsAIQCOALIMAAArsg8AACuxAwTpshgBACuxHwTpsh8YCiuzQB8cCSu0CAkPGA0rtAgEAB8EKwGwIi+wEtaxAAXpsAAQsQYBK7EKBemyBgoKK7NABggJK7AKELQMBQARBCuwDC+xIwErsQYAERKyDxgcOTk5sAwRsA05sAoSsBs5ALEIAxESsA05sAkRsQASOTkwMRMUFjMyNj0BIzUzESMnBiMiJjU0PgMzMhYXIy4BIyIGdU1iLmCJ4SwRTGxuiQ4kOF47XXYPVgtDP1VWAP9halVCDz3+4EhWmnwjSE87J1pSMyxrAAACAAr/GgHZAgwACgAgAFYAshEBACuwFDOwHi+0AQQANwQrAbAhL7AL1rQJBQAxBCuwCRCxAwErsRsF6bEiASuxCQsRErAQObADEbETHjk5sBsSsBY5ALERARESswYLExskFzkwMRYyNjU0JicOARUUJzQ+AjcDMxsBMwMeAxUUBiMiJuAiGx8LDSFREhQlBrtcjY1ZtwclFBNbKi5OoCUXDFYYGFcMFxMQOixSDgGf/sYBOv5hDk4tOBA+REAAAAACAAr/6AIeAh4AIwAvAJ4AshYAACuxKQTpsB4vsAszsQAE6bAEMrIeAAors0AeIQkrsAcyAbAwL7Ah1rQgBQAmBCuwIBCxGQErtCYFACYEK7AmELEtASu0EQUAJgQrsBEQsQgBK7QHBQAmBCuxMQErsSAhERKwIjmxJhkRErIAHR45OTmwLRGzAhYcDiQXObARErEECzk5ALEeKRESsw4RGSQkFzmwABGwAjkwMRMyFzYzMhYVIzQmIyIGBx4BFRQOAiMiJjU0NjcmIgYHIz4BFwYVFBYzMj4BNTQmojQ6OzU+YEwyHAsoDys8Gy0uGT1eOCklLjQDTARioUUtHRshCiwCHj8/kEEdZh8SQJIlNk8pElpmKZE/LlkpVH3DbUc/MycxHRdn//8APP8zAdwCDBALAEsCGAIMwAAAAQA8AAAB3ALcABwAWwCyCAAAK7AbM7IMAwArtBEEADcEK7IXAQArtAMEAEMEKwGwHS+wCNa0BwUAPAQrsBMysAcQsRwBK7QbBQA8BCuxHgErsRwHERKyDA4XOTk5ALEDCBESsBQ5MDEBNCYjIgYVESMRNDYzMhcVJiMiHQE+ATMyFhURIwGJQylATlNBOhcYFQg6JUs4TFlTAWs3MGFQ/t8CZTg/BUUCNpowJ01C/nQAAAAAAQA8/yYB3ALcACUAZACyCAAAK7IMAwArtBEEAEMEK7IXAQArtAMEAEMEK7AdL7QiBABDBCsBsCYvsAjWtAcFADwEK7ATMrAHELElASu0GwUAPAQrsScBK7ElBxEStAwOFx0fJBc5ALEDCBESsBQ5MDEBNCYjIgYVESMRNDYzMhcVJiMiHQE+ATMyFhURFCMiJzUWMzI2NQGJQylATlNBOhcYEwo6JUs4TFmPDQ8RAyYeAWs3MGFQ/t8CZTg/BUUBNZowJ01C/gdtA0cBHicAAAIADwAAAP0C2QADAA8AYACyDAAAK7IDAwArtAIEAB0EK7IFAQArtA8ODAUNK7AJM7QPBAA3BCuwBzIBsBAvsAzWsQIEMjK0CwUAPAQrsQAGMjKyCwwKK7NACwkJK7IMCwors0AMDgkrsREBKwAwMRMVIzUTNTMVMxUjFSM1IzWtVAFTUFBTSwLZaWn+X9TUSPDwSAABAEL/6QDrAgwADQAvALIJAAArtAQEAEMEK7INAQArAbAOL7AM1rQBBQA8BCuxDwErALENBBESsAY5MDETERQWMzI3FQYjIiY1EZUTGxkPJx0xNAIM/lUcEwRGBysoAdAAAAAAAQAUAAABAgIMAAsASwCyBwAAK7QIBAA3BCuwBDKyAAEAK7QLBAA3BCuwAjIBsAwvsAfWsAAytAYFAAkEK7ABMrQGBQAJBCuxDQErsQYHERKxAwk5OQAwMRMzFSMRMxUjNTMRIxTuSUnuUlICDEj+hEhIAXwAAAAAAQAUAAABxQLZAB8AnwCyHQAAK7IJAwArtBgSHQkNK7QYBAArBCuyEhgKK7NAEhYJK7QGAB0JDSu0BgQAKwQrsgAGCiuzQAADCSsBsCAvsAPWtAIFABEEK7ACELEdASuwCDKxHAXpsAoysBwQsRUBK7QWBQARBCuxIQErsQIDERKwBDmwHRGwBjmxFRwRErAYOQCxEhgRErAbObAAEbENHjk5sAYSsQgLOTkwMRMiByM+ATMyFxEzER4FMzI2NTMUIyIvAREjESZ+LwY1BDcxGhtUBRkIEQoNBh4VNWknKgJUIgFzTkZLDwEy/pwDDwQKAgMlJo8aAf7ZAV0WAAAAAAIAFAAAAZcC2QAPABUAZwCyCAAAK7IBAwArtAkQCAENK7ADM7EJBOmwBTK0ABEIAQ0rtAAEAEMEKwGwFi+wC9a0FAUAJgQrsBQQsQgBK7EAEDIysQcF6bACMrIHCAors0AHBAkrsRcBKwCxERARErELFDk5MDETNTMRMxUjESMRIjU0PgIXNSIGFRSrVJiYVJcPHz8qKCIB/9r+i03+6QEXcRMmJBiZUhkRKAABAET/JgDwAtkADAAiALIBAwArsAsvtAYEAEMEKwGwDS+wANaxAwXpsQ4BKwAwMRcRMxEUFjMyNxUGIyJEVB4mAxEPDZBtA0b82yceAUcDAAEAPP9xAkIC2QAeAHMAshkAACuyBAAAK7IaAwArshwBACu0FwQAQwQrsAYvsQ0E6QGwHy+wGdaxGAXpsBsyshgZCiuzQBgdCSuwGBCxEAErsQMF6bEgASuxGBkRErAIObAQEbIGCQA5OTkAsRkNERKwCDmwFxGzAxAJHiQXOTAxAR4BFRQGIyInNx4CMzI2NTQjIgc1NyERIxEzFSEVAYhZYYNtlTVJDxU3KUVOkxYaj/7cVFQBhwEUC2NYZXhnLhgZFktDggJLq/49AtnNSv//ADz/8QLwAgwQCwBQAywCDMAAAAEAPP84AvACDAAhAHsAsgoAACuwBTO0EwQAQwQrsBwysgoTCiuzQAoBCSuyDgEAK7EXIDMzAbAiL7AN1rEQBemwEBCxFgErsRkF6bAZELEfASuxIQXpsCEQtAEFACYEK7ABL7EjASuxFhARErAKObAZEbAHObAfErAFOQCxDhMRErEHAjk5MDEFIxEOASMiJw4BIyImNREzERQWMzI2NREzERQWMzI2NREzAvBNIks0YSwlSDRJT1QzLjNIVDMuM0hUyAESLypQLCRLRwGJ/pcyN1A5AUn+lzI3UDkBSQAAAQA8/yYC8AIbACoAewCyKgAAK7AgM7IAAQArsgUBACuwCjO0JQQAQwQrsBwysBAvtBUEAEMEKwGwKy+wKtaxKQXptAIFACYEK7ApELEhASuxIAXpsCAQsRgBK7EOBemxLAErsSEpERKwBTmwIBGwBzmwGBKyEAoSOTk5ALElKhESsQcCOTkwMRMzFT4BMzIXPgEzMhYVERQjIic1FjMyNjURNCYjIgYVESMRNCYjIgYVESM8TSJLNGEsJUg0SU+QDQ8RAyYeMy4zSFQzLjNIVAIMSi8qUCwkS0f+Cm0DRwEeJwG1MjdQOf63AWkyN1A5/rcAAAEACv8mAgMCGwAcAGAAsgoAACuyAAEAK7IFAQArtA4EAEMEK7AUL7QZBABDBCsBsB0vsBzWsRIF6bQCBQAmBCuwEhCxCgErtAkFADwEK7EeASuxChIRErAFOQCxChkRErASObAOEbECETk5MDETMxU+ATMyFhURIxE0JiMiBhURFCMiJzUWMzI2NWJNI1E6TFpTOjJATpANDxEDJh4CDFg3ME5B/nQBay84YVD+cm0DRwEeJwAAAAABADz/JgI2AhsAHABhALIcAAArsgABACuyBQEAK7QXBABDBCuwES+0DAQAQwQrAbAdL7Ac1rEbBem0AgUAJgQrsBsQsRMBK7EJBemxHgErsRMbERKwBTkAsRwMERKxCRM5ObAXEbIIFAI5OTkwMRMzFT4BMzIWFREUFjMyNxUGIyI1ETQmIyIGFREjPE0jUTpMWx4mAxEPDZA6MkBOVAIMWDcwTkH+KCceAUcDbQHYLzhhUP7fAAAAAQA8AAAB5wIMAAkARQCyBQAAK7ABM7IGAQArsAAzAbAKL7AF1rQEBQA8BCuwBBCxCAErsQEF6bELASuxCAQRErECBzk5ALEGBRESsQMIOTkwMQERIwMRIxEzExEB523rU2zrAgz99AGd/mMCDP5jAZ0AAAADAB7/6QH4AhsACgAQABYAZQCyBgAAK7EVBOmyAAEAK7EOBOm0EhAGAA0rtBIEADcEKwGwFy+wCdaxEgXpsBAysBIQsREBK7ALMrEDBemxGAErsRESERKzAA0PBiQXOQCxEhURErAIObAQEbADObAOErAJOTAxATIWFRQGIyImEDYFLgEiBgcFIR4BMjYBCnF9f25wfX4BBAhNgE4HASn+2AhOfE4CG5WIgZSVAQiV+VJaW1FGTlhYAAAAAAIAHv/pAt4CGwAJAB8AmwCyEwAAK7EQBOmyFgAAK7EFBOmyHgEAK7ELBOmyGwEAK7EABOm0DA8WGw0rsQwE6QGwIC+wGdaxAwXpsAMQsQcBK7ETHTIysRAF6bALMrIQBwors0AQDgkrs0AQEgkrsAoysSEBK7EHAxESsRYbOTkAsQUTERKwFDmxDxARErIDBxg5OTmxCwwRErICCBk5OTmxHgARErAdOTAxASIGFBYzMjc1JgUjFTMVIxUzFSE1BiMiJhA2MzIXNSEBC0ZQUEZfJiQBbvbU1Pr+sjdOcH1+bk44AUoBzm2+bWLUYg2OTJtMDyaVAQiVJRYAAAIAHv/3AroCHgAYAC8AaQCyLQAAK7ApM7QMBAA3BCuwFTKwBi+xHwTpAbAwL7AZ1rEJBemwCRCxDwErsRIF6bASELEAASuxJAXpsTEBK7EPCRESsR4tOTmwEhGxBis5ObAAErEfKTk5ALEGDBESsxAZJCskFzkwMSU0LgMjIgYVFBYzMjY9ATMVFBYzMj4BJTQ+AzIeAxUUDgIjIicGIyImAmYdLUVBKoJ4Mzo3LFQvMyg0Ev24DixHfKJ7RywPJDw9IWAwLmJeYOs6VDEcCXFzSWM5Id/fIjg1SDUpSlU9KCc9U0wqRmg0GFpakAAA//8AGP84ApgCyBACA2b6AP//ABT/8QEQAgwQCwBVAUwCDMAAAAEAFP/xARAC2QANADsAsgcAACuyDQAAK7EABOmyBAMAKwGwDi+wA9axBgXpsAYQtAcFACYEK7AHL7EPASsAsQQAERKwCDkwMTc+ATURMxEjNQ4BIyInFFRUVE0kQygLFUkCSmcB3f0nXzszAwAAAAABABT/JgFoAgwAFgBAALIWAAArsQAE6bIEAQArsA4vtAkEAEMEKwGwFy+wA9axBQXpsAUQtBAFACYEK7AQL7EYASsAsQQAERKwETkwMTc+ATURMxEUFjMyNxUGIyI9AQ4BIyInFFRUVB4mDAgPDYkkQygLFUkCSmcBEP2oJx4BRwNtzDszAwAAAQA8/zgBOAIbAA0AKACyBgEAK7ILAQArsQAE6QGwDi+wBdaxBAXptAgFACYEK7EPASsAMDEBDgEVESMRMxU+ATMyFwE4VFRUTSRDKAsVAcMCSmf+KALUXzszAwABADz/JgE4AhsAFgA6ALIPAQArshQBACuxAATpsAwvtAcEAEMEKwGwFy+wDtaxBAXptBEFACYEK7EYASsAsQAHERKwETkwMQEOARURFBYzMjcVBiMiNREzFT4BMzIXAThUVB4mAxEPDZBNJEMoCxUBwwJKZ/6kJx4BRwNtAnlfOzMDAAABADwAAAFcAhsADQA6ALIBAAArsgQBACu0CgQAQwQrsgoECiuzQAoHCSsBsA4vsAHWsQAF6bAAELEHASuxBgXpsQ8BKwAwMTMjETQgHQEjNCYnDgEVkFQBIFQaIiIaAa5tbSElHwEBHyUAAAABABT/OAE0AhsADQA7ALILAQArtAQEAEMEK7IECwors0AEAAkrs0AECAkrAbAOL7AI1rEHBemwBxCxAAErsQ0F6bEPASsAMDEXETQmJw4BFSM1NCAVEeAaIiIaVAEgyAJVJR8BAR8lIW1t/YoAAAAAAgA8AAACBwIMAA8AFwBbALIJAAArsAQzsgoBACuxFATptAcVCQoNK7EHBOkBsBgvsAnWsQgF6bAUMrAIELEQASuxAAXpsRkBK7EQCBESsQYDOTmwABGwBTkAsRUHERKwAzmwFBGwADkwMQEUBgcXIycjFSMRMzIeAgc0JisBFTMyAc9SQ81ny0VU+CxAIQ5bNiWJiVsBd0hMBt3a2gIMHjAvIy4nmwD//wBAAAACCwIMEAsDwwIVAgzAAAABACL/KAHLAhsAMAC4ALIkAAArsQUE6bISAQArsRcE6bIXEgors0AXFAkrsC8vtCoEAEMEKwGwMS+wANaxJwXpsAIysA8g1hGxGgXpsCcQsQgBK7EhBemwIRCwFCDWEbEVBemwFS+xFAXpsTIBK7A2Grrw2sHRABUrCg6wDBCwC8CxHQT5sB7AALMLDB0eLi4uLgGzCwwdHi4uLi6wQBoBsRUaERK2BRESJCosLyQXOQCxBSQRErAmObAXEbIBDyE5OTkwMRcRMx4BMzI2NTQmLwEuATU0NjIWFyMmIyIGFRQWHwEeARUUBiMiJxUUFjMyNxUGIyIiWAY1RTdDJitOXUlutmIBWANmMzwuM1BORnVjTi8eJgMRDw2QawEHLzctJR0iChMWQz5JV1RNVCskHCMMExNFOkxaGUwnHgFHAwAAAAABABT/JgEXAtwAFQA2ALIPAwArtBQEAEMEK7ADL7QIBABDBCsBsBYvsAvWtAEFADwEK7EXASsAsRQIERKxAQw5OTAxExEUIyInNRYzMjY1ETQ2MzIXFSYjIsCQDQ8RAyYfQToXGBMKOgJe/TVtA0cBHicCsTg/BUUBAAAAAQAU/yYBFgLcAB0AWwCyFQMAK7QaBABDBCuwBS+0CgQAQwQrsA8vsAEztBAEACsEK7AAMgGwHi+wDdawETK0AwUAPAQrsBwysgMNCiuzQAMBCSuwFzKyDQMKK7NADQ8JK7EfASsAMDEBFSMRFCMiJzUWMzI2NREjNTMRNDYzMhcVJiMiFREBFlePDQ8RAyYeRkZBOhcYEwo6AThE/p9tA0cBHicBQEQBLTg/BUUBNf7aAAAAAQAe/yYBIQIbABUANgCyBwEAK7QCBABDBCuwEy+0DgQAQwQrAbAWL7AV1rQLBQA8BCuxFwErALECDhESsQoVOTkwMRM0IyIHNTYzMhYVERQWMzI3FQYjIjV1OgoTGBc6QR8mAxEPDZABnTUBRQU/OP4QJx4BRwNtAAAAAAIAD/8mAcIC3AAKACYAZgCyFQMAK7QaBABDBCuwJC+0AwQAQwQrsAgvsQ8E6QGwJy+wC9a0AAUAJgQrsAAQsQYBK7ARMrQiBQA8BCuwHDKxKAErsQYAERKxDyQ5OQCxCAMRErMLHyAiJBc5sA8RsREdOTkwMRcUFjMyNjUmIyIGBzQ+ATMyFxE0NjMyFxUmIyIVERYXByYnFCMiJlwjKDAjPCIjHU0vOCAzMUE6FxgTCjoiUxoUR5xWTGcRGSAgEBcLKjURDQJlOD8FRQE1/YkKH0gHGXBJ//8AFAABAQQCtBALAFcBGAKdwAAAAQAU/yYBBAKcABUAagCyEQEAK7AAM7QQBAArBCuwATKyERAKK7NAERQJK7ALL7QGBABDBCsBsBYvsA7WsBIytAMFADwEK7AUMrIDDgors0ADAQkrsAgysg4DCiuzQA4QCSuxFwErALEGCxESsAk5sBARsAg5MDEBFSMRFBYzMjcVBiMiJjURIzUzNTMVAQRWExsZDycdMTRHR1MCDET91hwTBEYHKygCT0SQkAAAAAACAA7/6QJGAgwAFgAfAJQAsgEAACuyBQAAK7QbBABDBCuyDQEAK7ARM7QLCgUNDSuxFRczM7QLBAA3BCuxDxMyMgGwIC+wCNawDDK0GAUAPAQrsA4ysggYCiuzQAgKCSuwGBCxHgErsBAytBYFADwEK7ASMrAWELQBBQAmBCuwAS+yFgEKK7NAFhUJK7EhASuxHhgRErAFOQCxChsRErACOTAxISM1DgEjIiY9ASM1MzUzFTM1MxUzFSMhFRQWMzI2PQEB+EslUDpMW0lJU/tTTk7+sjoyQU5JNCxOQXhI1NTU1EhXLzhhUA0AAAEAHv/pAkICIAAqAFwAsgkAACu0HgQAQwQrsBMvsAAztBQEAEMEK7AoMgGwKy+wD9awEzKxGQXpsBkQsSQBK7EDBemwKTKxLAErsSQZERK1CRIVACcoJBc5ALETHhESswMPFickFzkwMQEeARUUDgMjIi4DNTQ2NyM1MxUOARUUHgIzMj4DNTQmJzUzFQHSMT8OJztkPkFmOSYMPzFu1Eg1EiVONCxFJxkINUjUAdcmfTsTPFBCLy9CUToUO30mSU0zdC4UPEkzIzE9LA8udDNNSQAAAQA8/+kB6gIMABsARgCyAQAAK7QJBABDBCuyBQEAKwGwHC+wBNa0BwUAPAQrsAcQsQ8BK7EWBemxHQErsQ8HERKxEhM5OQCxBQkRErETFjk5MDEXIyImNREzERQzMj4DNTQmJzceARUUDgPYNzE0U0ktRiYYCDVIZjE/Dic7ZBcrKAHQ/lUvIzE9KxAudDMEJn07EzxQQi8AAAD//wAKAAAB5gIMEAsAWQHwAgzAAP//AAoAAALIAgwQCwBaAtICDMAA//8ACgAAAdQC5hALAFwB3gIMwAAAAQAKAAAB8AIMAAgAMwCyAgAAK7IEAQArsAczAbAJL7AC1rQBBQA8BCuxCgErsQECERKwBjkAsQQCERKwBjkwMSUVIzUDMxc3MwEpU8xhlZFfysrKAUL29gAAAAABAB7/JwIgAgsAFABSALIBAAArtAgEAEMEK7ASL7QNBABDBCuwBC+0BQQAQwQrAbAVL7AU1rEKBemyFAoKK7NAFAEJK7EWASuxChQRErEHBjk5ALEECBESsQIHOTkwMQUhNQEhNSEVASEVFBYzMjcVBiMiNQF0/qoBOf7cAYf+yQFFHiYDEQ8NkAFLAXhJSv6HkyceAUcDbQAAAAACAB7/oAHeAgwAFQAfAJAAsgcAACuwAzO0DgQAQwQrsBoysgcOCiuzQAcECSuyCwEAK7QKBABDBCu0FhMECw0rtBYEAEMEKwGwIC+wBdawDzK0BAUAGwQrsBkysgUECiuzQAUKCSuwBBCxHgErtAAFABsEK7EhASuxHgQRErEJEzk5sAARsQwNOTkAsRYOERKxCAA5ObEKExESsA05MDElFAYjFSM1IzUBITUhFQEzNTQ2MzIWByIGHQEzMjY1NAHeU05I1wE5/twBh/7JckI0K0h0GBUKNxdfNilgYEsBeElK/ocdLT41FBUNHQwTIAABABT/cQHuAgwAGABtALIWAQArtBUEAEMEK7AGL7EMBOmyDAYKK7NADAgJKwGwGS+wCNaxCQXpsAkQsQ8BK7EDBemyDwMKK7NADxIJK7EaASuxCQgRErEVFjk5sA8RsgYAFDk5ObADErEXGDk5ALEVDBESsQMYOTkwMQEeARUUBiMiJzMeATMyNjU0KwE1NyE1IRUBNFlhg23aEFgFSEhFTpMwj/7cAYcBFAtjWGV45U1KS0OAS6tJSgAAAAIAHv92Af4CDAApADQAgwCyJwEAK7QmBABDBCuwDS+0MAQAQwQrsCovsRYE6QGwNS+wEta0LQUAJgQrsC0QsSABK7EDBemyIAMKK7NAICMJK7E2ASuxIC0RErQNFgAlMyQXObADEbIKKCk5OTkAsSowERKzBwgSCiQXObAWEbMDBR4gJBc5sCYSsgAiKTk5OTAxAR4BFRQHFhcHJicOASMiLgI1ND4BMzIeBRc2NTQrATU3ITUhFQMiBhUUFjMyNjcmARZZYQQhERoPJB1uSSk8Hw4vOCAOGRwPIAgnAgGTMI/+3AGHzSMdIygtRwtFARQLY1gYFwsGSAUMLzIYJiYTKjURAQUCCQMMAQgJgEurSUr+TRcPERkkEhoAAQAeAAAB1ALFABYAVACyEAAAK7IGAgArsQAE6bIABgors0AABAkrAbAXL7AE1rEDBemwAxCxEAErsQ8F6bAPELEUASuxCQXpsRgBK7EPEBESsQAGOTkAsQAQERKwCTkwMRMiBgcjNjMyFhUUBgcGBxEjET4BNTQm/Uw5AlgF2WVzQzgaH1RfT0MCeFNF5WhbOWYOBwT+tgGQAixBOEEAAAEAHgAAAdQCxQAWAFQAsgsAACuyFAIAK7EDBOmyAxQKK7NAAxYJKwGwFy+wEdaxBgXpsAYQsQsBK7EKBemwChCxAAErsRYF6bEYASuxCgsRErEDFDk5ALEDCxESsBE5MDEBLgEjIgYVFBYXESMRJicuATU0NjMyFwF8Aj1IOkNPX1QfGjhDc2XZBQHgSk5BOEEsAv5wAUoEBw5mOVto5f//AB4AAAHUAsUQCwI3AfICxcAAAAEAKP8rAp0C5QAfAFkAsgYDACuxDATpsgwGCiuzQAwJCSuwGS+xEwTpshMZCiuzQBMWCSsBsCAvsB/WsRAF6bAQELEWASuxFwXpsAkg1hGxCAXpsSEBK7EJEBESsgYTGTk5OQAwMRM0PgMzMhcjLgEjIgYdARQWMzI2NzMCISIuAzUoETBHeUzuK18QXldqe4BtWmARYCH+9Ut3Ry8RAWQyYmpPNO5OTqKMv4ihZWr+3zNOaGAxAP//ACj/6QLoAuUQJgAyAAAQAwMdAPv/kv//ADwAAAHKAgwQAgOmAAAAAgAe/+kB3AIbAA8AJACFALIDAAArsR8E6bINAQArsRAE6bQWGQMNDSuxFgTpAbAlL7AK1rETBemyEwoKK7NAExgJK7ATELAcINYRsQYF6bAGL7EcBemwExCxIgErsQAF6bEmASuxHAoRErAIObEiExESsgMNHzk5OQCxGR8RErAGObAWEbIIACI5OTmwEBKwCjkwMQEUBiMiJjU0NyY1NDYzMhYnIgYVFBY7ARUjIgYVFBYzMjY1NCYB2256Y3JWQXBcfl7fMz8xMCk1Kzs9Nk9HPwEGnIFaTFYmJUtJV3wvKyQhNUw2HyUtX21zWQAAAQAe/+kCWgIgACoAqQCyDAAAK7IPAAArsQME6bIYAQArsBwzsSgE6bIoGAors0AoJAkrsBgQtCEEAEMEK7QICQ8YDSu0CAQAHwQrAbArL7AS1rEABemwABCxBgErsCUysQoF6bIGCgors0AGCAkrsAYQsSQF6bAKELQMBQARBCuwDC+xLAErsQYAERKyAw8YOTk5sAwRsQ0aOTkAsQgDERKwDTmwCRGxABI5ObEYIRESsBo5MDETFBYzMjY9ASM1MxEjJwYjIiY1ND4DMzIXNjMyFxUmIyIdASMuASMiBnVNYi5gieEsEUxsbokOJDheO2M7Hk4XGBMKOlYLQz9VVgD/YWpVQg89/uBIVpp8I0hPOycyNwVFATUzMyxrAAD//wA8AAAB3gIMEAIDsQAAAAMADv8mAcEC2QADABYAIQBvALIDAwArtAIEAB0EK7ILAQArsBQvtBoEAEMEK7AfL7EIBOkBsCIvsATWtBcFACYEK7AXELEdASuxAgoyMrQSBQA8BCuxAAwyMrEjASuxHRcRErEIFDk5ALEfGhESsw8EEBIkFzmwCBGxCg05OTAxARUjNQM0PgEzMhcRMxEWFwcmJxQjIiY3FBYzMjY1JiMiBgFMU+svOCAzMVMiUxoUR5xWTE0jKDAjPCIjHQLZaWn8xCo1EQ0CDP3bCh9IBxlwSSoRGSAgEBcAAP//AAr/NwHGAhAQCwBOAgICEMAAAAEAPAAAAXICDAAFACwAsgAAACuxAwTpsgEBACsBsAYvsADWsQMF6bIDAAors0ADBQkrsQcBKwAwMTMRMxEzFTxU4gIM/kBMAAIAHv8mAkoCigALACQAYwCyHQAAK7EGBOmyHQYKK7NAHRkJK7IjAQArsQAE6bAVL7QQBABDBCsBsCUvsCDWsQMF6bADELEaASuxCQwyMrQZBQA8BCuxJgErsRoDERKxHSM5OQCxAAYRErIMGyA5OTkwMQEiBhUUFjMyNjU0Jhc1NDYzMhcVJiMiBhURIxEGIyImNTQ2MzIBDkVUVEVCUE9VPDkXGBMKHhxTOWloeHxoZwHNcFtcb25aXnADSTk+BUUBGB39GgEWU5R/gp0AAAABAB4AAAHUAsUAHgCEALIUAAArsgYCACuxAATpsgAGCiuzQAAECSu0FhcUBg0rsA8ztBYEADcEK7ARMgGwHy+wBNaxAwXpsAMQsRQBK7AYMrETBemwDjKyExQKK7NAExEJK7IUEwors0AUFgkrsBMQsRwBK7EJBemxIAErsRMUERKxAAY5OQCxABcRErAJOTAxEyIGByM2MzIWFRQGBwYHFTMVIxUjNSM1MzU+ATU0Jv1MOQJYBdllc0M4Gh9tbVRpaV9PQwJ4U0XlaFs5Zg4HBBJI8PBIWAIsQThBAAAAAAEAHgAAAdQCxQAeAIQAsg8AACuyHAIAK7EDBOmyAxwKK7NAAx4JK7QREg8cDSuwCjO0EQQANwQrsAwyAbAfL7AZ1rEGBemwBhCxDwErsBMysQ4F6bAJMrIODwors0AODAkrsg8OCiuzQA8RCSuwDhCxAAErsR4F6bEgASuxDg8RErEDHDk5ALEDEhESsBk5MDEBLgEjIgYVFBYXFTMVIxUjNSM1MzUmJy4BNTQ2MzIXAXwCPUg6Q09faWlUbW0fGjhDc2XZBQHgSk5BOEEsAlhI8PBIEgQHDmY5W2jlAAAAAwAe/+kDhQLZAAsAIAAjAJMAshEAACu0DgQAQwQrshUAACuxBgTpsh4DACuyIAEAK7QhBABDBCuyGwEAK7EABOkBsCQvsBjWsQMF6bADELEJASuwHTK0IgUAPAQrsB8ysiIJCiuzQCINCSuzQCIPCSuxJQErsQkDERKxFRs5ObAiEbEREjk5ALEOBhESsBI5sCERtAkNAxgiJBc5sAASsB05MDEBIgYVFBYzMjY1NCYlFQEhFSE1DgEjIiY1NDYzMhcRMx0BEQEBDURUVEVCUFACJ/7JAUX+JCJPNmp6e2ZsNVMBIQHNcFtcb25bXm8/Sv6HSUUxK5mFfZdRAQ/NSf6lAVsAAAAAAgAe/3EDogLZACoANgC+ALIZAAArsh0AACuxMQTpsgQAACuyJgMAK7IoAQArtBcEAEMEK7IjAQArsSsE6bAGL7ENBOkBsDcvsCDWsS4F6bAuELE0ASuwJTK0FwUAPAQrsCcyshc0CiuzQBcqCSuwFxC0GQUAGwQrsBkvsBcQsRABK7EDBemxOAErsTQuERKxIx05ObEXGRESsAg5sBARsgYJADk5OQCxHQ0RErAIObExGRESsAk5sBcRtgMQGiAqLjQkFzmwKxKwJTkwMQEeARUUBiMiJzceAjMyNjU0IyIHNTchESM1DgEjIiY1NDYzMhcRMxUhFSUiBhUUFjMyNjU0JgLoWWGDbZU1SQ8VNylFTpMWGo/+30oiTzZqentmbDVTAYT9lkRUVEVCUFABFAtjWGV4Zy4YGRZLQ4ICS6v+PUUxK5mFfZdRAQ/NSgtwW1xvbltebwAEAB7/oAOdAtkACwAWADcAOgDnALIdAAArsBoztDAEAEMEK7AQMrIiAAArsQYE6bIiBgors0AiGwkrsisDACuyLQEAK7Q4BABDBCuyKAEAK7EABOm0DDUbKA0rtAwEAEMEKwGwOy+wJdaxAwXpsAMQsQkBK7AqMrQ5BQA8BCuwLDKyOQkKK7NAOS8JK7A5ELEcASuwMTK0GwUAGwQrsA8ysBsQsRUBK7QXBQAbBCuxPAErsQkDERKxIig5ObA5EbEeHzk5sBwSsDA5sRUbERKxNTo5OQCxMAYRErAfObAMEbEXOTk5sTg1ERKzCQMvJSQXObAAEbAqOTAxASIGFRQWMzI2NTQmASIGHQEzMj4BNTQXFAYjFSM1ITUOASMiJjU0NjMyFxEzFSEVATM1NDYzMhYBEQEBDURUVEVCUFAB2RgVCiYiBklTTkj+9SJPNmp6e2ZsNVMBhv7JckI0K0j+VgEjAc1wW1xvblteb/67FQ0dBwoOICk2KWBgRTErmYV9l1EBD81K/ocdLT41ASf+ogFeAAEAFP/pAqMCnAAxAN0AsiEAACuxAATpsg4BACuxEwTpsicBACuwKzO0JgQAKwQrsC0ysicmCiuzQCcqCSuyEw4KK7NAExAJKwGwMi+wJNawKDK0LwUAPAQrsCoysi8kCiuzQC8tCSuyJC8KK7NAJCYJK7AvELELASuxFgXpsBYQsQQBK7EdBemwHRCwECDWEbERBemwES+xEAXpsTMBK7A2Grrw2sHRABUrCg6wCBCwB8CxGQT5sBrAALMHCBkaLi4uLgGzBwgZGi4uLi6wQBoBsREWERKxDQ45OQCxJgARErILFh05OTkwMTczMjY1NCYvAS4BNTQ2MhYXIyYjIgYVFBYfAR4BFRQGIyEiJjURIzUzNTMVMxUjERQW3PYySCYrTl1JbrZiAVgDZjM8LjNQTkZ2Yv71MDVHR1NWVhE2LiQdIgoTFkM+SVdUTVQrJBwjDBMTRTpMWisoAYxEkJBE/p0dEgAAAAIAFP8mAfgC3AAjACsAlQCyDgAAK7QqBABDBCuyHQMAK7QiBABDBCuyFAEAK7AYM7QTBAArBCuwJTKyFBMKK7NAFBcJK7ADL7QIBABDBCsBsCwvsBHWsBUytCcFADwEK7AXMrIRJwors0AREwkrsCcQsQsBK7EZJDIytAEFADwEK7EtASuxCycRErIDBQ45OTkAsQ4IERKwATmxIhQRErAAOTAxAREUIyInNRYzMjY9AQYjIiY1ESM1MzUzFTM1NDYzMhcVJiMiAxEjERQWMzIBoZANDxEDJh9zGzE0R0dToEE6FxgTCjpToBMbFAJe/TVtA0cBHidDDisoAYxEkJBZOD8FRQH9qgGL/pkcEwAAAgAU/40C7gKcADcAQQEdALItAAArsSQnMzO0BgQAQwQrsRo8MjKyLQYKK7NALSUJK7IzAQArsAAztDIEACsEK7ABMrINAQArsRQE6bIUDQors0AUEQkrsjMyCiuzQDM2CSu0OB4lNg0rtDgEAEMEKwGwQi+wMNawNDK0AwUAPAQrsDYysgMwCiuzQAMBCSuyMAMKK7NAMDIJK7ADELEKASuxFwXpsBcQsSYBK7AaMrQlBQAbBCuwOzKwJRCxEQErsRAF6bAQELAhINYRtEAFABsEK7BAL7QhBQAbBCuxQwErsQoDERKyBistOTk5sBcRsAg5sCYSsg0UKTk5ObERJRESsR44OTmxEEARErAPOQCxBi0RErApObA4EbEIITk5sTIeERKxChc5OTAxARUjERQWMzI3JjU0NjMyFhcjLgEjIgYVFBYzNTQ2MzIWFRQGIxUjNSInDgIjIiY1ESM1MzUzFQEiBh0BMzI2NTQBBFYTGwthLn9qW20HVAhANERNTkZCNCtIU05IUDoNWU0IMTRHR1MBzBgVCjcXAgxE/pkcExxGaYKcYl03O29iXWodLT41PTYpYGAqAxgTKygBjESQkP5pFQ0dDBMgAAEAFP85AuIC3AAwAJ0AshkAACuwFDOyIQMAK7QmBABDBCuyHAEAK7ApM7QbBAArBCuwFjKyLgEAK7QQBABDBCuwBC+0CQQAQwQrAbAxL7AZ1rAdMrQYBQA8BCuwKDKyGRgKK7NAGRsJK7AYELEVASuxFAXpsBQQsQwBK7EBBemxMgErsRUYERKxISM5ObAUEbEqKzk5sAwSsgQGLjk5OQCxGxkRErArOTAxARMUBiMiJzUWMzI2NRE0JiMiBhURIxEjESMRIzUzNTQ2MzIXFSYjIh0BMxU+ATMyFgLhAUpGDQ8RAyYeOjJATlSTU0ZGQToXGBMKOuAjUTpMWgGM/ho1OANHAR4nAaQvOGFQ/t8ByP44AchEWTg/BUUBNVJYNzBOAAABADz/6QJyAtkAKAC3ALICAAArsicAACuxCATpsgMDACuyFQEAK7EaBOmyGhUKK7NAGhcJKwGwKS+wAtaxAQXpsAQysAEQsRIBK7EdBemwHRCxCwErsSQF6bAkELAXINYRsRgF6bAYL7EXBemxKgErsDYauvDawdEAFSsKDrAPELAOwLEgBPmwIcAAsw4PICEuLi4uAbMODyAhLi4uLrBAGgGxGB0RErMIFBUnJBc5ALEIAhESsAA5sBoRsgUSJDk5OTAxNxUjETMRHgEzMjY1NCYvAS4BNTQ2MhYXIyYjIgYVFBYfAR4BFRQGIyKQVFQroEY3QyYrTl1JbrZiAVgDZjM8LjNQTkZ1Y4wyMgLZ/bgmNS0lHSELExdCPklXVE1UKyQcIwwTE0U6TFoAAAAAAgA8AAACJQLZAAgACwBOALIFAAArtAIEAEMEK7IGAwArsggBACu0CQQAQwQrAbAML7AF1rEKBemwBzKyCgUKK7NACgAJK7NACgQJK7ENASsAsQkCERKxAQo5OTAxARUBIRUhETMdAREBAhf+yQFF/hdUASQCDEr+h0kC2c1J/qEBXwD//wAw//8B+QLaEC8AWgAqAYUpmRAOAFoqACmZAAIAHgB3AcgCaAAHAA8AXgCwDS+0CAQANwQrsAgQtA8EAA8EK7AKMrAFL7QABAA3BCuwABC0BwQADwQrsAIyAbAQL7AP1rAAMrQOBQAbBCuwBTKwDhCxCwErsAMytAoFABsEK7ABMrERASsAMDETIRUjNSEVIxUhFSM1IRUjHgGqRv7iRgGqRv7iRgJoiUND34lDQwABAAr/OgICAtwAHABpALIIAwArtAMEAEMEK7ISAQArsBkvtA4EAEMEK7IZDgors0AZFQkrAbAdL7Ac1rQLBQA8BCuwCxCxFQErsBEytBQFADwEK7EeASuxFQsRErAZOQCxEg4RErILFhw5OTmwAxGxAAo5OTAxEzQmIyIHNTYzMhURFBYzMjY1ETMRIxEOASMiJjViHiYDEQ8Nj0MpQE5TUyVLOExZAk4nHgFHA23+KDcwYVABK/0uAQQwJ01CAAABAAr/JgJZAtwAJQBmALIaAwArtBUEAEMEK7AHL7QCBABDBCuwDi+0IAQAQwQrsiAOCiuzQCAkCSsBsCYvsBHWtB0FADwEK7AdELEKASuwIzK0AAUAPAQrsScBK7EKHRESsA45ALEVIBESshELHDk5OTAxBRQzMjcVBiMiJj0BDgEjIiY1ETQmIyIHNTYzMhURFBYzMjY1ETMCAjoKExgXOkElSzhMWR4mAxEPDY9DKUBOU1w1AUUFPzihMCdNQgHYJx4BRwNt/ig3MGFQASH//wAaAYUBKQNgEA8AS//zAYYpmf//ABoBhgEpA2IQDwIJ//MBhimZ//8AGAEIAIgDcBAPAE0AGAGWKZn//wAgAYUAxQLkEA8AVf/5AYUpmf//ACMBfADIAtsQDwBVAO8C29ZmAAEAGgD4APgC2gAVADoAsgQDACuwDi+0CQQAEwQrsBUvtAAEAB8EKwGwFi+wA9awEDK0BQUAEQQrsRcBKwCxBAARErAROTAxEz4BPQEzERQWMzI3FQYjIj0BBiMiJxo3NzYTGQoEBwxZLDELCgG1ATBDsf56GRQBLgJHhEcCAAD//wAqAYYBVgLcEAsDwwFcAtvWZv//ABgBhgHhAtwQDwBaABIBhymZ//8ACgD3ATUC2xAPAFwABAGGKZn//wAxAbYA4gLMEAYMjwAA//8AMQG2AbICzBAnDI8A0AAAEAYMjwAAAAEAVQH3AL4C8gAKADsAsAEvtAkEAB0EK7AFL7QEBAATBCsBsAsvsAHWtAAFADAEK7QABQAwBCuwBDK0CQUAEQQrsQwBKwAwMRMjNTQzFQ4BHQEzvmlpIhU3Afd4gyYBJTUSAAABAFAByQC5AsQACgBDALIAAgArtAoEAB0EK7AEL7QFBAATBCsBsAsvsATWsAAytAIFADAEK7QCBQAwBCuwAhC0CAUAEQQrsAgvsQwBKwAwMRMzFRQjNT4BPQEjUGlpIhU3AsR4gyYBJTUSAAABAFUByQC+AsQACgA9ALIKAgArtAIEAB0EK7AHL7QGBAATBCsBsAsvsAnWtAEFADAEK7QDBQARBCu0AQUAMAQrsAYysQwBKwAwMRMVIxUUFhcVIj0BvjcVImkCxGgSNSUBJoN4AAAA//8AWQJDALEC8hAPAmIBAAU1wAAAAQBPAkMApwLyAA0AQACwCC+0BwQAEwQrsAEvtAAEABMEKwGwDi+wC9a0BAUAEQQrsgQLCiuzQAQACSuwBzKxDwErALEBBxESsAs5MDETFSIGFRQWMxUiJjU0NqcSGhoSJDQ0AvIsGhESGiw0JCM0AAEAGAGQATUC/QAXAE8AsAAvtAcEABMEK7IABwors0AABAkrAbAYL7AE1rQDBQARBCuwAxCxEQErtBAFABEEK7AQELEVASu0CgUAEQQrsRkBK7EQERESsAA5ADAxEyIGByM+ATMyFhUUBgcGBxUjNT4BNTQmqTIlATkCSUVCSywkERQ3PjMrAso2LUpLQzwlQgkFAnWiAR0qJSoAAAEAGAGQATUC/QAXAE8AsAMvtBQEABMEK7IDFAors0ADFwkrAbAYL7AR1rQGBQARBCuwBhCxCwErtAoFABEEK7AKELEAASu0FwUAEQQrsRkBK7EKCxESsAM5ADAxEy4BIyIGFRQWFxUjNSYnLgE1NDYzMhYX/AEoLyYrMz43FBEkLEtCRUkCAmcwMyolKh0BonUCBQlCJTxDS0oAAAEAHAIhATAC7gAGAHUAsAYvtAIEAAoEKwGwBy+wANawATK0BQUACAQrsAMysQgBK7A2GroSwcLPABUrCrACLgSwAcCxAw75DrAEwLrs7sLoABUrCgWwBi4EsADAsQUO+bEEAwiwBMAAtAABAwQFLi4uLi4BsgIEBi4uLrBAGgEAMDETNSUVBxcVHQET3t4CeR1XIURFIgD//wAcAiEBMALuEA8CZQFMBQ/AAAABADMCPgEaAu4ABgA4ALAGL7ACM7QABAAMBCsBsAcvsAbWtAIFAAkEK7EIASuxAgYRErMAAwEFJBc5ALEABhESsAQ5MDETMxcjJwcjliFjJk1OJgLur42NAAAA//8AMwI+ARoC7xAPAmcBTQUtwAAAAQAUAk8BMwLlAAYALQCyAAMAK7QGBAAOBCuwAjIBsAcvsAbWtAIFAAcEK7EIASsAsQAGERKwBDkwMRMzFyMnByN0X2A/UU9AAuWWYGAAAAABABMCTwEyAuUABgAtALIDAwArsAUztAEEAA4EKwGwBy+wAta0BgUABwQrsQgBKwCxAwERErAEOTAxEyMnMxc3M9JfYD9RT0ACT5ZgYAAA//8AWQJMAKEDERAHArABKAAAAAD//wAcAncBLgK9EAIAcQAA//8AXAJRAS0C5RACAHYAAf//ABYCUADnAuQQAgBDAAAAAQBZ/v0Aof/CAAMAJwCwAS+0AgQACwQrAbAEL7AB1rQABQAbBCu0AAUAGwQrsQUBKwAwMRMjNTOhSEj+/cUA//8AHf90AS//uhAHAHEAAfz9AAD//wBT/zcBJP/LEAMAQwA9/OcAAP//ACP/OAD0/8wQBwJt/8f85wAA//8AZwAAAOUCIhAvAnQBTAIiwAAQBgJ0AAAAAAABAGcBsADlAiIAAgAgALACL7QABAASBCsBsAMvsADWtAEFABAEK7EEASsAMDETMwdnfj8CInIA//8AXP//ALQArhAPAmIBAwLxwAD//wBTAAIAqwCxEAcCYgAE/b8AAAABAAsAlQFCAZIABwBEALAGL7QHBAA3BCuwAzKyBwYKK7NABwEJKwGwCC+wANa0AwUAGwQrsgMACiuzQAMFCSuyAAMKK7NAAAYJK7EJASsAMDE3NTMVMxUhNYRGeP7J27e3Rkb//wALAJUBQgGSEA8CdwFNAifAAAABAAsAbgFCAaYACwBYALAFL7AAM7QGBAA3BCuwCjKyBQYKK7NABQMJK7IGBQors0AGCQkrAbAML7AD1rAHMrQCBQAbBCuwCTKyAgMKK7NAAgAJK7IDAgors0ADBQkrsQ0BKwAwMSUjFSM1IzUzNTMVMwFCeUZ4eUZ453l5Rnl5AAEACwDnAUIBLQADACgAsAIvtAMEADcEK7QDBAA3BCsBsAQvsQIBK7QBBQAHBCuxBQErADAxARUhNQFC/skBLUZGAAAAAQAPAlUBPALcAAwAPgCyAAMAK7AGM7AJL7QDBAArBCsBsA0vsADWtAEFABEEK7ABELEGASu0BwUAEQQrsQ4BK7EGARESsAk5ADAxEzMWMzI2NzMGIyIuAQ87CFQoMAM7C40kPDQC3EIiIIcTQAAAAAEAcwJkANsCzAADAC4AsAIvtAMEAB0EK7QDBAAdBCsBsAQvsALWtAEFADoEK7QBBQA6BCuxBQErADAxExUjNdtoAsxoaAAAAAIAPQIxAREDBAAKABUATACwBi+0EQQAHwQrsAsvtAAEAB8EKwGwFi+wCNa0DgUAGwQrsA4QsRMBK7QDBQAbBCuxFwErsRMOERKyBQYAOTk5ALELERESsAM5MDETMhYVFAYiJjU0NhciBhUUFjI2NTQmpyw+P1Y/PysSGhokGhkDBD4sKz0+Kyo/PhoREhoaERMZAAABADn/MwEJAAAAEAA1ALIGAAArsAAvtAwEABMEKwGwES+wA9a0CgUAGwQrsRIBKwCxDAARErAPObAGEbEDDjk5MDEXIiY1NDY3Mw4BFRQzMjcVBr04TDMuRjcnSCUaMM00KiQ6ER8sHzYKLQoAAAAAAQAFAmUBPwLNABAAMwCwCC+wDTO0AwQAKwQrswsDCAgrtAAEACsEK7AFMgGwES+wDta0BgUABwQrsRIBKwAwMRMyFjMyNzMGIyImIyIHIz4BWxlYFBkMOg9KFGQOFwo6CC0CzSUlaCYlMTYAAgAAAk4BTQLkAAMABwAeALIAAwArsAQztAMEAA4EK7AGMgGwCC+xCQErADAxEzMHIzczByMzcWg83HGBPALklpaWAAABAAAA6gFBAjoAEgApALAPL7EHBOmyBw8KK7NABwMJKwGwEy+wAdaxFAErALEHDxESsA05MDERNTczHgIzMj4CNxUGIyImJ0pFBy8jEA4XCxUELSotThEBjGNLE5tODw8mB3Ito18A//8AEwJVAToDGhBHAJn/zAJEMAAgAAAA//8ACwDuATgC2hAPAgYABAGEKZn//wA1AYUAbQNgEA8ATwAOAYYpmf//ABsBfwExAu4QDwBWAAYBjymZ//8ADQGGATYC3BAPAFsABwGHKZn//wANAYYBKwNTEA8COP/6AYYpmQABACgAAAHGAyAABQAwALICAAArsAQvtAUEADcEKwGwBi+wAta0AQUAGwQrsgIBCiuzQAIECSuxBwErADAxAREjESE1AcZI/qoDIPzgAthIAAEAKAAAAcYDIAAHAD4AsgIAACuwBC+0BQQANwQrsgUECiuzQAUHCSsBsAgvsALWsAYytAEFABsEK7ICAQors0ACBAkrsQkBKwAwMQERIxEhNSE1AcZI/qoBVgMg/OACM0ilAAABACgAAAHGAyAABwA+ALICAAArsAQvtAUEADcEK7IFBAors0AFBwkrAbAIL7AC1rAGMrQBBQAbBCuyAgEKK7NAAgQJK7EJASsAMDEBESMRITUhEQHGSP6qAVYDIPzgAW5IAWoAAQAoAAABxgMgAAcAPgCyAgAAK7AEL7QFBAA3BCuyBQQKK7NABQcJKwGwCC+wAtawBjK0AQUAGwQrsgIBCiuzQAIECSuxCQErADAxAREjNSE1IREBxkj+qgFWAyD84KVIAjMAAAEAKAAAAcYDIAAFADgAsgEAACu0AgQANwQrsgIBCiuzQAIECSsBsAYvsAPWtAAFABsEK7IDAAors0ADAQkrsQcBKwAwMSkBNSERMwHG/mIBVkhIAtgAAAABAEj//wHfAl4ABQA4ALIAAAArtAMEADcEK7IDAAors0ADAQkrAbAGL7AA1rQDBQAbBCuyAwAKK7NAAwUJK7EHASsAMDEXETMRIRVISAFPAQJf/elIAAAAAQBIAAAB3wJmAAcAPgCyAgAAK7AAL7QFBABDBCuyBQAKK7NABQMJKwGwCC+wAta0AQUAGwQrsAQysgECCiuzQAEHCSuxCQErADAxExEjETMRIRWQSEgBTwER/u8CZv70SQAA//8AF/84ATb/zhAHAmoABPzpAAD//wAcAlEBLgMgECYAcQBjEAYAcQDaAAD//wBQAfEBTQLZEAYMegAA//8AM/83ARr/5xAPAmcBTQImwAD//wAu/zcBFf/nEAcCZ//7/PkAAP//ABr/IwEu//AQBwJl//79AgAA//8AG/8kAS//8RAHAmb///0DAAD//wA6/v4BDv/REAcCff/9/M0AAP//ABYBbgDnAgIQBwJuAAD/HgAA//8AAAFuAU0CBBAHArIBnv8gAAD//wAAAXABTQIGEAcCgAAA/yIAAP//AAn/YwFD/8sQBwJ/AAT8/gAA//8AUABBALgCTRAGAB0AQQABABgCAACwAu0ABQA2ALADL7QABAA3BCuyAwAKK7NAAwUJKwGwBi+wBda0BAUAGwQrsgQFCiuzQAQCCSuxBwErADAxEzMVIxUjGJhQSALtSKUAAAABABoCAACyAu0ABQA2ALAEL7QFBAA3BCuyBAUKK7NABAIJKwGwBi+wAta0AQUAGwQrsgIBCiuzQAIECSuxBwErADAxExUjNSM1skhQAu3tpUgAAP//ABj/twCwAKQQDwKdAMoCpMAA//8AGP+4ALAApRAPApwAyAKlwAAAAQAL/zgBQv/kAAcAQgCwBC+0BQQADAQrsAIytAcEADcEK7QFBAAMBCuwATIBsAgvsATWtAcFABsEK7AHELEAASu0AwUAGwQrsQkBKwAwMRc1MxUhNTMV+kj+yUiAZKysZAAAAAEAC/84AUL/5AAFADYAsAIvtAUEADcEK7IFAgors0AFAwkrAbAGL7AC1rQFBQAbBCuyBQIKK7NABQEJK7EHASsAMDEFFSE1MxUBQv7JSIBIrGQAAAEAAP8kAU3/7QASACMAsg4AACuwAi+0EgQAEwQrAbATL7EUASsAsRICERKwCjkwMQUVIRYfAQcnJi8BNzY/ARcHBgcBTf7yGRkEFQQlMwQEMyUEFQQZGWgfHSAEFAUrMAQFMCsFFAQhHAAA///+yQJQ/5oC5BADAEP+swAAAAD///8PAlD/4ALkEAMAdv6zAAAAAP///scCT//mAuUQAwJp/rMAAAAA///+uAJl//ICzRADAn/+swAAAAD///7PAnf/4QK9EAMAcf6zAAAAAAAB/j0CdQBzAr0AAwAgALIDAgArtAIEADcEK7IDAgArtAIEADcEKwGwBC8AMDETFSE1c/3KAr1ISAAAAP///sICVf/vAtwQAwJ7/rMAAAAA////JgJk/44CzBADAnz+swAAAAD///7MAmT/5wLMEAMAav6zAAAAAAAB/uQCNP99AvUAFABaALACL7QDBAAfBCuwAxC0AAQAEwQrsAovtA8EABMEKwGwFS+wAta0AQUAEQQrsAEQsQcBK7QSBQARBCuxAQIRErIKDA85OTkAsQoDERKxDBI5ObAPEbANOTAxAxUjNTMyNjU0JiMiByc2MzIWFRQG2ywsEhgbDxQNIBwlKDA0AkYSQBgRFxUQIBwyJiQzAP///vACMf/EAwQQAwJ9/rMAAAAA///+yAJPABUC5RADAoD+yAABAAD///7GAk//5QLlEAMCav6zAAAAAAAB/zECTP95AxEAAwAjALABL7QCBAALBCsBsAQvsAHWtAAFABsEK7QABQAbBCsAMDEDIzUzh0hIAkzFAP///uwCTP/FAxEQJgKwTAAQBgKwuwAAAAAC/mICTv+vAuQAAwAHABoAsgQDACuwADO0BgQADgQrsAEyAbAILwAwMQMXIycjFyMnhDM8aDhMPIEC5JaWlpb///7CAlX/7wMvECMCfP6zAGMQAwJ7/rMAAAAA///+wgJV/+8C3BALAnv//gUxwAD///8pAkf/gQLqEAsCtv6zBSvAAAAB/zICQf+KAuQACgA2ALIAAwArsQoE6bAFL7QGBAATBCsBsAsvsAXWsAAysQIF6bECBemwAhC0CQUAEQQrsAkvADAxAzMVFAYjNTI2NSPOWC8pGRQtAuRJKy8qFRoAAAAB/ywCQf+EAuQACgAwALIKAwArsQIE6bAGL7QFBAATBCsBsAsvsAnWsQEF6bEBBemwBTK0AgUAEQQrADAxAxUjFBYzFSImPQF8LRQZKS8C5EoaFSovK0n//wAAAkIAWALlEAMCtgDOAAEAAP///sn/OP+a/8wQAwBD/rP86AAA///+/v84/8//zBADAHb+ovzoAAAAAf7o/t//tf/NAAcAQACwBS+0BgQANwQrsgUGCiuzQAUDCSuyBgUKK7NABgAJKwGwCC+wA9awADK0AgUAGwQrsgMCCiuzQAMFCSsAMDEHMxUjNSM1M5NISIWFM+5TSAD///8B/uD/zv/OEA8Cu/62/q3AAAAB/zUBqwBHAr0ABQA0ALIAAgArtAUEADcEK7IFAAors0AFAwkrAbAGL7AD1rQCBQAbBCuyAwIKK7NAAwUJKwAwMQMhESM1I8sBEkbMAr3+7swAAAAB/3cBuABDAosADQAuALIHAQArsQYE6bAEMgGwDi+wC9axAgXpsgsCCiuzQAsGCSuxAgsRErAAOQAwMRMWFRQjMCM1Mz4BNTQnHiWfLUkYFxECiys4cFQBCxIXFAAAAP///yD/Jv94/9UQBwJ2/s3/JAAAAAH+5P84/9L/0wAHAEAAsAAvtAEEADcEK7AFMrIBAAors0ABAwkrAbAIL7AC1rQFBQAbBCuyBQIKK7NABQcJK7ICBQors0ACAAkrADAxBTUzNTMVMxX+5FNIU8hIU1NIAAH+5P84/9L/0wAHAEAAsAYvsAEztAcEADcEK7IGBwors0AGBAkrAbAIL7AE1rQDBQAbBCuyAwQKK7NAAwEJK7IEAwors0AEBgkrADAxBxUjFSM1IzUuU0hTLUhTU0gAAAH+5P7g/9L/zgALAFQAsAYvsAEztAcEADcEK7AAMrIGBwors0AGBAkrsgcGCiuzQAcJCSsBsAwvsATWsAgytAMFABsEK7AKMrIDBAors0ADAQkrsgQDCiuzQAQGCSsAMDEHFSMVIzUjNTM1MxUuU0hTU0iFSFNTSFNTAP///lj/ZP+P/6oQBwJ6/k3+fQAAAAH/Vf8mAAAALQAOACoAsAUvtAsEAEMEK7ILBQors0ALAAkrsAIyAbAPL7AO1rQDBQA8BCsAMDEnMDMVFCMiJzA1FjMyNjVTU48NDxEDJh4tmm0DRwEeJwAB/63/JgBYAC0ADgAtALAKL7QFBABDBCuyBQoKK7NABQAJK7ANMgGwDy+wDNa0AgUAPAQrsAAyADAxNTAVFBYzMjcVBiMiPQEwHiYDEQ8Njy15Jx4BRwNtmgAA///+8v9b/1r/wxADAnz+f/z3AAD///6T/17/rv/GEAMAav56/PoAAP///q//Af+D/9QQAwJ9/nL80AAAAAH+8/7U/1f/tAAMADoAsAYvtAcEABMEK7AML7QABAAeBCsBsA0vsAbWsAAysQIF6bECBemwAhC0CQUAEQQrsAkvsAszADAxBTMVFAYrATUyNTA1I/7zZDQuAjc3TGc4QSZOCP///pD/Kv+IAAAQAwB6/mkAAAAA///+7P8z/7wAABADAn7+swAAAAD///79/w3/Rf/SEAcCsP/M/MEAAAAB/s//O//h/8QABwA+ALAHL7ACM7QABAAPBCu0AAQADwQrsAAQtAUEADcEKwGwCC+wB9a0BgUAGwQrsAYQsQMBK7QCBQAbBCsAMDEFIRUjNSMVI/7PARJGhkY8iUNDAAAB/sD/VP/y/84AHgBaALAIL7AEM7QRBAATBCuwGjIBsB8vsAvWtA4FABEEK7AOELEUASu0FwUAEQQrsBcQsR0BK7QBBQARBCuxFA4RErAIObAXEbAGObAdErAEOQCxEQgRErAGOTAxBxUUBiMiJwYjIiY9ATMVFBYzMjY9ATMVFBYzMjY9AQ4zJSYbGyckMywaERMZLBoRExkyIiUzHh40JCIiEhoZEyIiEhoZEyIA///+xv84/+X/zhADAmr+s/zpAAD///7G/zj/5f/OEAsCav/4Ah3AAP///sL/OP/v/78QAwJ7/rP84wAA///+wv84/+//vxALAnv//gIUwAD///59/0X/t/+tEAMCf/54/OAAAP///pD/Z/+i/60QAwBx/nT88AAA///9p/9Q////ghAHAEL9vQAAAAD///2n/ur///+CECcAQv29/5oQBwBC/b0AAAAA///+PgDQ/3gBOBAHAn/+Of5rAAD///5lAOj/dwEuEAMAcf5J/nEAAP///TkA3v+RARAQBwLV/5IBjgAAAAH9QwAD//MCaAADAAADMwEjWUz9nEwCaP2bAAAB/UP/w//zAu0AAwAAAzMBI1lM/ZxMAu381gD///74/wP/UP+yEA8Cv/5w/tjAAP///pb/UP+o/9kQDwLN/nf/FMAAAAL+lP7U/5n/2QADAAcANACwAy+0BwQAKwQrsAYvtAAEACsEKwGwCC+wA9a0BwUAGwQrsAcQsQQBK7QCBQAbBCsAMDEFIREhNzUjFf6UAQX++8F9J/77RH19AAAAAf6C/1L/tP/FABoAWgCwFy+wDjO0AwQAEwQrsAcyAbAbL7AA1rQaBQARBCuwGhCxEwErtBIFABEEK7ASELELASu0CgUAEQQrsRMaERKwAzmwEhGwBTmwCxKwBzkAsQMXERKwBTkwMQU0NjMyFzYzMhYVIzQmIyIGHQEjNTQmIyIGFf6CMyUmGxsnJDMsGhETGSwaERMZkyUzHh40JBIaGRMbGxIaGRMAAf7SAjP/0wL0AAsAPwCwBC+wBjO0AAQACwQrsAoyAbAML7AJ1rAHMrQBBQAIBCuwAzKxAQkRErMABAIIJBc5ALEABBESsQULOTkwMQMXBxcHJwcnNyc3F04gX18gYF8gX18gXwLzGEdIGEdHGEhHGEcAAAAB/yECRv+JA1IAEAAvALADL7QEBAATBCsBsBEvsAnWsAMytA4FABsEK7MGDgkIK7QABQAbBCuwCzIAMDEDFAYHNTY1NCY1NDcVBhUUFnc2MSUmaCUlAoYYIgYsBhINZxE3DCwJEw1l///9qAJNAAAC5RAHAtYAAQNjAAD///7JAlH/mgLlEAMAQ/6zAAEAAP///w8CUP/gAuQQBgKkAAD///6oAlz/4gLEEAcCf/6j//cAAP///zICQf+KAuQQBgK2AAD///6dAlj/5AL2EAcDG/6X/+wAAP///r//Vv9b//YQAwMV/kAAHgAA///+zwJR/+EC2hAHAs0AAAMWAAD///6M/y//nv/ZECYC1PwsEAYC1PzIAAD///64/xH/jf/WECYCzEgEEAYCzLsEAAAAAf7y/xP/gv+jAAUAMgCwBS+0AAQAHwQrsgUACiuzQAUDCSsBsAYvsAPWtAIFABsEK7IDAgors0ADBQkrADAxBTMVIzUj/vKQPVNdkFcAAAAB/o8CU//JAxIAGABNALILAwArsBQztAUEACsEK7ILBQors0ALDgkrshICACu0FwQAKwQrsAcyAbAZL7AI1rQVBQAHBCsAsQUXERKxAwA5ObELEhESsA05MDEDByM3JiMiByM+ATMyFzczBxYzMjczBiMiyR5DKw8IFwo6CC0hGSUnPjEKCRkMOg9KEgKHNEcFJTE2D0BUAiVoAP///mgCL/+iA4QQIwJ8/jD/yxAjAnz+kgC4EAMCf/5jAEEAAP///pECPf/LAywQIwJ//owAXxADAn/+jP/YAAD///3g/w3/1P/TEEcNkf3U/xMgABgAAAAAAf6U/tT/Wf/JAAwAJACwAS+0BwQACQQrAbANL7AB1rQABQARBCuxAAERErAHOQAwMQMjNQYHJzY3FhcHJif/FRI5DTQuOCsNQQr+1MoULA0tMTklDTUL///+ugIh/84C7hAHAmb+ngAAAAD///86Ak3/kgL8EAcCvwAaAycAAP///qECM//OAyAQIwJ8/pL/zxALAnv/3QV1wAD///5Q/xr/Uf/bEAcC4P9+/OcAAP///mr/I/9+//AQBwKU/lAAAAAA///+e/8k/4//8RAHApX+YAAAAAAAAv4T/yb/4//XAAYADQB4ALACL7EJDDMztAYEAAwEK7AHMgGwDi+wNhq6EsHCzwAVKwqwAi4OsAHAsQMP+bAEwLrs7sLoABUrCgWwBi4OsADAsQUQ+bEDBAiwBMAAtAABAwQFLi4uLi4BtgABAgMEBQYuLi4uLi4usEAaAQCxBgIRErALOTAxBRUHNTcnNSUzFyMnByP+/em8vAFLIWMmTU4mdRlKHDo7HAGvjY0AAP///zsCPf+TAuwQDwJi/+IFL8AA///+vQJ8/yUC5BADAnz+SgAYAAAAAf5t/uT/Uv+8AA4ALwCwCS+wBzO0AAQACgQrAbAPL7AO1rQCBQARBCuxAg4RErAIOQCxAAkRErAIOTAxBTMHNxcHFwcnByc3JzcX/sgvBFAOUTUnLi8mNFEOUERUHCwWQxtGRhtDFiwcAAAAA/38/xz/pP/QADAASQBiAGgAsCkvsBoztDQEABMEK7BKMrBHL7BQM7QABAATBCuwEjIBsGMvsCzWtDEFABEEK7AxELFNASu0FwUAEQQrsU0xERK1EhopAD5ZJBc5ALFHNBESQAkGDBciJCwxCk0kFzmwABGwBTkwMQUyHgcXPgYzMh4CFRQGIyIuBTEOBSMiJjU0PgIHFBYzMj4HNyIuBiMiBgUyNjU0JiMiDgYHHgj+VwgREQ4RChEFDwEBFAkVEBYVCxkmEwkyJA4cGBYRDAkEGwsaERsOJDIJEyYhHR8GDQ0KDQcOBQ8CAQ4GEAoRDhAHGh8BKh8dHxoIEA0RCw8HDQECDwUOBw0KDQ0xAwcGDAYOBQ4BARIIEQkKBRUfGgoiOAcMDQ8MCQQYCREIBjgiChsfFFwQKAIFBAoFDQQPAQwGDAcKBQQmTSgQFSYEBQoHDAYLAQEPBA0FCgQFAgAAAAAB/q8CIv+ZAyAABwAyALAGL7QCBAAfBCuyBgIKK7NABgQJK7ICBgors0ACAAkrAbAIL7AH1rQDBQAJBCsAMDEBMwc3ByM3I/7nQSWWOT8nmQMgZQGaXwAAAf6z/zkBTv/dAB0AQgCwES+0AQQAKwQrsgERCiuzQAEYCSuwCDIBsB4vsBjWtBkFABEEK7AZELEIASu0CQUAEQQrsQgZERKxEBE5OQAwMQYyNjc+AzczDgMHDgEiJicuAyczHgEXFjx4eSQTExYKAS4CESIjHyJ4eXgiHyMiEQIuAiAlJIMSDAcIDxUPIC0eEgoMEREMChIeLSAdGA0M///+twJlAVIDCRAHAv8ABAMsAAAAAf67AmMBRQKkAAMAGQCwAy+0AAQAKwQrtAAEACsEKwGwBC8AMDEBIRUh/rwCiP14AqRB///+u/9tAUX/rhAHAwEAAP0KAAAAAf6oAjkBTALjABkAVACyBwMAK7QABAArBCuyAAcKK7NAAAQJK7AVL7QMBAArBCuyDBUKK7NADBAJKwGwGi+wD9a0EAUAEQQrALEMFRESsBc5sAARsQoYOTmwBxKwCTkwMQMiBgcjPgEzMh8BFjMyNjUzFA4CIyIvASayM0MFKwZXTCoqtywiQywzHDE3ID1BmSUCoCokRksQRREgKyk7Hg0aPw4AAAD///6zAngBTgMcEA8C/wABAlXAAAAB/tP++wEr/+IACgAaALAAL7QBBAATBCsBsAsvALEBABESsAY5MDEFNSEnNxYXBgcnN/7UAeRFJTlZWTklRaguPxwzQD8zHEAAAAD///6jAjn/XwMQEA8ARP6YAkIYUf///pECOv9GAxAQDwBI/oYCQxhR///+4wI//wMDVRAPAEz+ygI/GFH///6QAjr/RQMQEA8AUv6FAkMYUf///qsCOv9KAwsQDwBY/pUCQxhR///+swI7/14DERAPAEb+qAJEGFH///6kAjr/WANYEA8AR/6aAkMYUf///rUCOf9UA1AQDwBL/p4COhhR///+aQI8/3EDCRAPAFD+UwI8GFH///7dAjz/PgMJEA8AVf7HAjwYUf///s4COv8qA0EQDwBX/scCQxhR///+kwI6/0kDAhAPAFn+kAI6GFH///6aAjr/SAMCEA8AW/6XAjoYUf//ADEBtgDiAswQBgJcAAAAAQAW/z4AiwAGAAMAIACwAy+0AQQACgQrAbAEL7AA1rQCBQAaBCuxBQErADAxFzcXBxZqC0KCiECIAAAAAQB//zgBG//YAA8ARwCwCS+0AAQAEwQrsgAJCiuzQAAFCSuzQAAMCSsBsBAvsAvWtA4FACYEK7AOELEFASu0BgUAEQQrsREBK7EOCxESsAk5ADAxFzI+AjczFAYjIj0BMxUU5QsKAwQBGSExSkyjAwMOBCoTT1FPLAAAAAEAIv/0AZgCEgAcAEsAshUAACuwEzO0GgQANwQrshUAACuxFwTpsggBACuwCjO0AwQANwQrsggBACuxBgTpAbAdL7AA1rEQBemxHgErALEGFxESsBA5MDEBNCYjIgcjNTM2MzIeAxUUBiMiJyM1MxYzMjYBPlFHIRxHUhMfI0BBMB6CcB8TUkccIUdRAQNVcAxSBA4mO2I+jIMEUgxwAP//AB7/9AGUAhIQJwB5AKD/9hAGA2sAAP//ACL/9AGYAhIQJgB5CvYQBgMWAAAAAP//AFD/bQC5AgwQAgAeAAD//wBzAlABRALkEAcCpAFkAAAAAAADAAYCbAFNAwoAAwAHAAsARwCyBwIAK7AIM7EGBOmxAgkyMgGwDC+wBta0BQUAPAQrsAUQsQoBK7QJBQA8BCuxDQErsQoFERKyAAIDOTk5sAkRsAE5ADAxEzMHIycVIzUhFSM1slphOhdTAUVTAwqeVVNTU1MAAP//AAUAAAKLAuUQAgwgAAAAAQBWAaQAvgIMAAMANQCyAwEAK7QCBAAdBCuyAwEAK7QCBAAdBCsBsAQvsALWtAEFADoEK7QBBQA6BCuxBQErADAxExUjNb5oAgxoaAAAAP//AAAAAALzAuQQJwMpAJgAABAGAxqNAP//AAAAAAMaAuQQJwMrAJkAABAHAqQA8QAAAAD//wAAAAABSQLkECcDLQCHAAAQBgMajQD//wAA/+kDOgLlEAIMVxYA//8AAAAGA24C5RACDEw3AP//AAAAAAL1AuQQJwKkAPEAABAGAzwoAP///+n/+AEwAv0QIgMb4/MSAgNMAAAAAP//AA8AAAKLAtkQAgAkAAD//wBQAAACcALZEAIAJQAAAAEAUAAAAjQC2QAFACwAsgMAACuyBAMAK7EBBOkBsAYvsAPWsQIF6bICAwors0ACAAkrsQcBKwAwMQEhESMRIQI0/nxgAeQChf17AtkAAAAAAgAOAAACrALZAAMABgAiALIBAAArsQQE6bICAwArAbAHL7EIASsAsQIEERKwBjkwMSkBATMDIQMCrP1iAQh09gGO0ALZ/XsCOwAA//8AUAAAAlsC2RACACgAAP//AB4AAAJJAtkQAgA9AAD//wBQAAACgQLZEAIAKwAAAAMAKP/pAugC5QADAA4AGABiALIHAAArsRQE6bIMAwArsQ8E6bQCAQcMDSuxAgTpAbAZL7AK1rESBemwEhCxFgErsQQF6bEaASuxFhIRErMBBwwAJBc5ALEBFBESsQkSOTmwAhGxBBY5ObAPErEKETk5MDEBITUhFxQGIyImEDYzMhYlIgYQFjI2NTQmAiv+sAFQvcCgnsLCnaDB/p90jo/oj44BQFIxotbTAVbT1IKl/vKlpISKpv//AGQAAADCAtkQAgAsAAD//wBQAAACkwLZEAIALgAAAAEADwAAAosC2QAGACEAsgEAACuwBDOyAgMAKwGwBy+xCAErALECARESsAY5MDEzIwEzASMDcmMBBHgBAGjVAtn9JwJ1AAAA//8AUAAAAv4C2RACADAAAP//AFAAAAKKAtkQAgAxAAAAAwAoAAACSgLZAAMABwALACkAsgEAACuxAgTpsgYDACuxBQTptAoJAQYNK7EKBOkBsAwvsQ0BKwAwMSkBNSEDITUhAyE1IQJK/d4CIgj97gISOf5nAZlTAjNT/nNTAAD//wAo/+kC6ALlEAIAMgAAAAEAUAAAAoAC2QAHAC8AsgUAACuwADOyBgMAK7EDBOkBsAgvsAXWsQQF6bAEELEBASuxAAXpsQkBKwAwMSEjESERIxEhAoBe/oxeAjACh/15AtkA//8AUAAAAl4C2RACADMAAAABACgAAAJeAtkACwAoALIBAAArsQoE6bIFAwArsQgE6QGwDC+xDQErALEIChESsQIEOTkwMSkBNRMDNSEVIRMDIQJe/crsygIA/nTK8gHIVQEjAQ9SUv7x/tkA//8AHgADAloC3BACADcAA///AA8ABgKXAt8QAgA8AAYAAwAoAAACuwLZABEAGAAfAHIAshEAACuyBwMAK7QAGREHDSuwFjO0AAQAKwQrsA8ytAYaEQcNK7AVM7QGBAA3BCuwCTIBsCAvsAPWsR0F6bAdELERASuxBhkyMrQQBQA8BCuxCBUyMrAQELESASuxDAXpsSEBKwCxGhkRErEMAzk5MDElIiY1NDYzNTMVMhYVFAYjFSMBNCYnET4BBREOARUUFgFIe6WlfFF9pKV7UwEYb1ZXbv7oVm9uX5V9eZ5RUZ94fJZfAXZWawn+YwlyewGdCWxVWXH//wAPAAACggLZEAIAOwAAAAEAPAAAAr4C2QAbAFcAsgMAACuyCQMAK7AYM7IKAgArsRAXMzO0BQ4DCg0rsBIzsQUE6bAAMgGwHC+wCNaxCwXpsAsQsQ8BK7ADMrESBemwATKwEhCxFgErsRkF6bEdASsAMDElIxUjNSMiJjURFxEUFjsBETMRMzI2NRE3ERQGAc4iXiJ6dlpLVxpWGldLWoKrq6tsYQFhFP7JUUEByf43QVEBNxT+n2tiAAABACgAAALNAt0AIQBqALIQAAArsCAztBEEADcEK7IADh4yMjKyGAMAK7QIBABDBCsBsCIvsBXWsQsF6bALELEFASuxGwXpsSMBK7ELFRESsRAROTmwBRG2AA4PEhgeISQXObAbErEfIDk5ALEIERESsRUbOTkwMSU+AzU0JiMiBhUUFhcVITUzLgE1NDYzMhYVFAYHMxUhAa8WO0QujnFth2lN/vikT1q7jprCaFSw/u5MCS9Nd0FxmqBuY7QjTEgurGWKzMKQaa4sSP////4AAAEZA4QQIwBq/+UAuBACAy0AAP//AA8ABgKXA4QQIwBqALMAuBACAzgAAP//AB7/8wI1AuQQIwMaAJYAABICA0QAAP//AB7/9gHTAuQQIgMaewAQAgNIAAAAAP//AA//SgHpAuoQIwMaAIUABhACA0oAAP//ADz/+AErAugQIgMa5wQQAgNMAAAAAP//ADz/8gHyAv0QIgMbYPMSAgNYAAAAAAACAB7/8wI1AhMAGgAlAHQAshIAACuwGTOxDQTpsCMysgkBACuyBgEAK7EeBOkBsCYvsADWsSEF6bAhELEbASuxCwXpsAsQtAgFABsEK7AIL7EnASuxGyERErAZObAIEbEVFjk5sAsSsBI5ALENEhESsRAWOTmwHhG0AAgPGyEkFzkwMRM0PgMzFhc1MxEUMzI3FwYjIiY9AQ4BIyIBNCYjIgYVFDMyNh4MIDFTNH4sSBULDBUrJR4jDlU/5AF4UkJKRo5ITgEGIUNLOSUCV1L+Vx8JRRUgGxMjKgEWTm5pW8BmAAACADz/OgICAtwAFAAoAIwAsg8AACuxHgTpsg8eCiuzQA8TCSuyBQMAK7QYBAA3BCu0JSQTBQ0rsSUE6QGwKS+wFNaxEwXpsBsysBMQsSEBK7EMBemwFSDWEbQIBQAbBCuyFQgKK7NAFSQJK7EqASuxFRMRErMFDwoeJBc5ALEeDxESsBI5sCQRsRwMOTmwJRKwCjmwGBGwCDkwMRM0PgIzMhYVFAcWFRQGIyImJxUjATQmIyIGFREWMzI2NTQrATUzMjY8EipRO19paJ5vXztGIVYBSD80RzgfcUFFojIqP0cB6jdSRSRkWHclHp5fdx4k+gLoMz9QXv6qVEpEiEpJAAAAAAEACv86AfwCGAASACwAsgoBACuwADOyDQEAK7EHBOkBsBMvsAPWsQIF6bEUASuxAgMRErAROQAwMQEDFSM1AyYjIgcnNDYzMhYXGwEB/LxWpwYTDA4GJAYuJxV2kAIM/hrs7AGYDgZGAwkjN/7QAX4AAAAAAgAe//ACCgLZABsAJwB0ALIWAAArsSIE6bIHAwArtAoEADcEK7QDHBYHDSu0AwQAKwQrAbAoL7AA1rEfBemwHxCxJQErsREF6bEpASuxHwARErEGBzk5sCURswMKFgUkFzmwERKxCQg5OQCxHCIRErEAETk5sAMRsAU5sAoSsAY5MDE3NDYzMhcnNSEVIRceBBUUDgIjIi4DNyIGBxQWMzI2NTQmHnZfChjTAY7+868ZFjUcGDFQUisgPUExH/RGUgJQRE9XUvJzjgSiSEiKFBI5MlAsS244GQ4kOF35Z09bXWNXUmIAAAEAHv/2AdMCFAAkAJcAsgMAACu0IgQANwQrsiIDCiuzQCIACSuyDQEAK7QUBAA3BCuyFA0KK7NAFBEJK7QcGQMNDSu0HAQAHwQrAbAlL7AF1rAJMrQfBQA8BCuwFjKyHwUKK7NAHxsJK7AfELEkASuwETK0AAUAJgQrsBAysSYBK7EkHxESsgMNBzk5OQCxHCIRErAFObAZEbAHObAUErAJOTAxJQ4BIyI1NDcmNTQ+ATMyFhcjLgEjIhUUFjsBFSMiBhUUFjI2NwHTC21n1mZmRFk5WHwLTAVWO4FAQC4uP0FIclgFiFBCkl8eHWA3RRZETiclVS8oOygvLCglJwABAB7/PgGwAs4AHABTALAKL7QLBAA3BCsBsB0vsAbWsRAF6bAQELEaASu0FQUAMQQrsR4BK7EQBhESsQoLOTmwGhGzAAkSGCQXObAVErMNEwwXJBc5ALELChESsA05MDEFIi4DNTQ2NyM1IRUOARUUFx4BFRQHJzY1NCYBHhU3TD0riWfgAWRxp61FRCZMIh0ECR8uVDaK3kJIPEDihI4UBS5BN2EcRSEjGQAAAQAP/0oB6QITABwAWACyBwAAK7IVAQArsA8zsQME6bAKMgGwHS+wB9axBgXpsAYQsRwBK7EbBemxHgErsQYHERKxDxM5ObAcEbAVObAbErAXOQCxAwcRErEMEzk5sBURsA05MDEBNCYjIhURIxE0IyIHJzYzMhYfATYzMhYXFhURJwGRLj6KWBYFCw4eHyAkAgFDYVJbBAFYATxFRar+5AGeJQNICzElD2RRTgcs/goYAAAAAwAe//QB2wLaABIAGgAkAFsAsgYAACuxIQTpsg4DACu0EwQANwQrtBUcBg4NK7QVBAA3BCsBsCUvsAzWsRwF6bAVMrAcELEbASuwFjKxAAXpsSYBK7EbHBESsQ4GOTkAsRUcERKxDAA5OTAxARQOAyMiLgM1EDMyHgInIhEhNC4CEyEUHgIyPgIB2wodMFE2N1IwHArfQFsvFN6JARMLGzpg/u0KGjpWOhsKAWg/ZWRDKSlBZWRBAXI+bnvf/wA1UU8r/rg2U1UuLVRUAAAAAAEAPP/4ARICDAANAC8AsggAACuxAwTpsgwBACsBsA4vsAvWsQAF6bEPASsAsQMIERKwBjmwDBGwBTkwMTcUFjMyNxcGIyImNREzlBsVECAeLiw8QFiIGh8PURVIRQGHAAEAPAAAAeoCDAALADAAsgUAACuwADOyBgEAK7AJMwGwDC+wBdaxBAXpsAcysQ0BKwCxBgURErECCDk5MDEhIwMHFSMRMxU3MwcB6mysPlhY0HLGAQo8zgIM0tLGAAAAAAEACv/0AhgC2gAiAD0AsiIAACuyGwAAK7EVBOmyCQMAK7EFBOkBsCMvsSQBKwCxFSIRErAZObAFEbQABhAYICQXObAJErAHOTAxEy4DIwc3NjMyHgYXExYzMjY3FwYjIi4BJwsBI9AODBogGDYKIRcUJBobDhcGFgKmCBQFGgMUMCEZIQ4JepJgAggnHykNCFIMDAwhEjAQOgX+ShMIA0YYGBsbAWL+XAAAAAABADz/OAHgAgsAGQBPALIWAAArsgAAACuxDQTpsgANCiuzQAAFCSsBsBovsAXWsQQF6bAHMrAEELESASuwFjKxFAXpsRsBK7ESBBESsAA5ALENFhESsQMXOTkwMQUiJicVIxEzFRQXHgEzMjY3Nj0BMxEjNQ4BAQ4rNhlYWAwLOCkqPQYRVlAYOwweIvwC0994IyMqMRQ3auH99T4lJQD//wAKAAAB5gIMEAIAWQAAAAEAHv8+AccCzgAvAKYAsgwAACu0AAQANwQrsCsvtCgEAB8EK7AeL7AhM7QfBAA3BCsBsDAvsBHWsS4F6bAuELAlINYRtBoFACYEK7AaL7QlBQAmBCuyJRoKK7NAJSEJK7NAJSkJK7IaJQors0AaHgkrsC4QsQgBK7QDBQAmBCuxMQErsSUuERKwHTmwCBGzAAYMFyQXObADErAFOQCxKwARErARObAoEbAXObAeErAaOTAxJTIWFRQHJzY1NCYrASIuAjU0PgM3LgE1NDY3IzUhFSMiBhUUFjsBFSMiBhQWARRqSSdKIyY4E0NhMRUcJzMiEDZELCBkAXSmKkBMWFJuSmReRipDPV4cViIcEiE3OB8uSCkdCwIISzkrSBFGRlQwK0VAUnhEAAAAAAIAHv/2AgICFAAQACAARwCyDgAAK7ERBOmyBgEAK7QZBAA3BCsBsCEvsADWsR0F6bAdELEUASuxCwXpsSIBK7EUHRESsQ4GOTkAsRkRERKxCwA5OTAxEzQ+AzMyHgIVFAYjIiYXMjY1NC4CIg4CFB4CHh8wQj4hK05NLodtcX/wPlweMTE0MTAdHC8xAQ49XzglDRg2bUuGko9FXGw4USkSEipScFIqEgAAAAABABT//AJIAgwAFgBiALIFAAArsAsztAAEACsEK7IPAQArtA4EADcEK7EJETIyAbAXL7AM1rELBemyDAsKK7NADA4JK7ALELEIASuxEwXpshMICiuzQBMRCSuxGAErALEABRESsAM5sA4RsAI5MDElMjcXBiMiJjURIxEjESM1IRUjERQeAQIaEgwQMBouLOxeRgIoQAIOQAw+EjBGAVT+OgHGRkb+rhQRDwAAAgA8/zgCIAIUABAAIABZALIMAAArsREE6bIMEQors0AMDwkrsgYBACu0GQQANwQrAbAhL7AQ1rEPBemwHDKwDxCxFAErsQkF6bEiASuxFA8RErEMBjk5ALERDBESsA45sBkRsAk5MDETND4DMzIWFRQGIyInESMTMjY1NC4CIg4CFB4CPB8wQj4hcoKHbWM1WPA+XB4xMTQxMB0cLzEBDj1fOCUNj3eGkkf++wEIXGw4USkSEipScFIqEgABAB7/SgH9AhgAJABVALIDAQArsQoE6bIKAwors0AKBgkrAbAlL7AA1rEPBemwDxCxIAErsRoF6bAGMrAaELEHBemwBy+xJgErsSAPERK0AwoWHSMkFzmxGgcRErAcOQAwMRM0NjMyFhUjNCYjIg4CFRQeAxceAxUUByc+ATU0Jy4BHox0Y3xbSkIaMDEdHSc/LB8lNjgdMFoLHnNnowEUdo51X0BGESdMNC1EJRkJAwQMGSsfLG4gFlAOGwUFnAACAB7/9AJKAhQAEQAcAGEAsg8AACuxFQTpsgUBACuxGwTpsgcBACuxCgTpAbAdL7AA1rESBemwEhCxGAErsQwF6bIMGAors0AMCQkrsR4BK7EYEhESsQ8FOTmwDBGwCjkAsQoVERKzAAwSGCQXOTAxEzQ+AjMyFyEVIxYVFAYjIiY3FBYzMjY1NCYiBh4sS08sFhwBCIhAgXFzf1pbPUlPTJhMAQRNcDkaBlJSZnuVlHxrW2xaVnByAAAAAAEAFP/0AdgCDAARAEkAsgAAACuxDQTpsgYBACu0BQQAQwQrsAgyAbASL7AD1rEKBemyCgMKK7NACggJK7IDCgors0ADBQkrsRMBKwCxBQ0RErAPOTAxBSImNREjNSEVIxEUFjMyNxcGATJJMaQBxMgRIQ0UEyMMQ1EBO0lJ/s0rHQVPCgAAAAABADz/8gHyAgwAEwA3ALIMAAArsQME6bISAQArsAczAbAUL7AR1rEABemwABCxBgErsQkF6bEVASuxBgARErAMOQAwMTcUFjMyNjURMxEUBiMiLgI1ETOUMVNONFhqbkVaLhFY6GJIS18BJP66flYbOkg3AUYAAAACAB7/OAKpAgwAGgAjAHAAsgAAACuwFjOxDQTpsCAysgANCiuzQAAZCSuyEAEAK7EfBOkBsCQvsAPWsQoF6bAKELEZASuwDjKxGAXpsB8ysBgQsRsBK7ETBemxJQErsRkKERKxBgc5OQCxHw0RErIDChM5OTmwEBGxBwY5OTAxBSImNTQ2NxcOARUUFjsBETMyFhUUBisBFSM1ATQmKwERMzI2ASd5kFpGKjNDaU4UWHmbhm4gWAEYXU8UGEtdCpZuWookRCFkO05pAcWYem6Wvr4BBU9o/pVmAAAAAQAK/ywCOQIaAB4APACyFwEAK7ITAQArsQ4E6bAQMrADL7EcBOkBsB8vsSABKwCxHAMRErIACAk5OTmwDhG0CgcWGR4kFzkwMQUGKwEiJi8BAyMTAy4BIwYjNTYzMh8BEzMDFxYzMjcCORkaCCQ9EmG4aOqVDBUZDQsYIEIgg51gx4MQJA4UyAwzJsX+7gFoAQQWEAROBjz0ASL+lPskBgAAAAABADz/OAJ+AgwAFwBcALIGAAArsAMzsQ8E6bASMrIGDwors0AGBQkrsg8GCiuzQA8QCSuyCgEAK7AWMwGwGC+wCdaxDAXpsAwQsQUBK7APMrEEBemwETKwBBCxFQErsQAF6bEZASsAMDElFAYjFSM1IiY1ETMRFBYzETMRMjY1ETMCfoF1VnSCWkdVVlVHWtZsbMbGam4BNv7mWVEBsv5OUVkBGgAAAAABAB7/9wK6Ag4AJwBsALIWAAArsBIztCIEADcEK7ADMrIcAQArsAozAbAoL7AZ1rEfBemwHxCxJQErsQAF6bAAELEHASuxDQXpsSkBK7ElHxESshwWHTk5ObAAEbAUObAHErIJChI5OTkAsRwiERKzDRQZJiQXOTAxJRQWFzI+ATU0JzceARUUDgIjIicGIyImNTQ2NxcGFRQWMz4BPQEzAZYuNCg0EmxQKkYkPD0hYDAuYl5gPDRQbDM6NyxUmSI1AzVIL5R1GiKtTkZoNBhaWpBqPLgpGmydSWMDNyDf////2v/4ARICvxAiAGrB8xACA0wAAAAA//8APP/yAfICvxAiAGpo8xACA1gAAAAA//8AHv/2AgIC6BAjAxoAkAAEEAIDUgAA//8APP/yAfIC6BAiAxpxBBACA1gAAAAA//8AHv/3AroC6BAjAxoA7gAEEAIDXAAAAAIAHv/0AhUC2gAGADIAgQCyJAAAK7EvBOmyLyQKK7NALyoJK7IRAwArtAAEADcEK7QEMiQRDSuwHTO0BAQANwQrsBsyAbAzL7Aq1rQrBQAxBCuwKxCxCQErsQMF6bADELEyASuwBDKxHgXpsBsysh4yCiuzQB4dCSuxNAErsQMJERKwCjmwMhGxES85OQAwMQEiBhUzNCYDND4HMzIeBxUzFSMOBCMiLgMnMx4CMzI2NQErNyCqHuIBAwcMEhoiLBwbLCEZEQsGAwFDQwINIDFMMjROLBwKAlABGj4tQUkCkmmXl2n+uDE/UDI6IiQSDAwTIiAzJ0AqI0hBZVg4ICY4U0crO15AdpYAAAABABQAAAKpAuUAIABMALIZAAArsgoDACuwAjOxEQTpsgoDACu0AAQAKgQrAbAhL7AZ1rEYBemxIgErsRgZERKwBzkAsQAZERKyBw4POTk5sQoRERKwDDkwMRMwNTIeAhc+ATMyFw4BByYjIg4DHQEjNTQuAicmFERmPiEMEpVQSz4LIAsnJg4nQDImYAUULiYtAoVgM1pRM16zRQ4kDi4NOVy2eL6+RVRwXys0AAAA//8AAAAAA2oC5RAiAxqN/xADA2MAwQAA//8AFAAAAqkDhBAjAGoAhAC4EAIDYwAAAAMAHv84Ap4CyAATABoAIQBxALIRAAArsA4zsRcE6bAfMrIRFwors0AREAkrsgMBACuwBjOxGATpsB4ysgMYCiuzQAMECSsBsCIvsADWsRQF6bAUELEQASuxAxcyMrEPBemxBR4yMrAPELEbASuxCQXpsSMBKwCxGBcRErEJADk5MDETNDYzNTMVMhYVFA4CIxUjNSImNxQWMxEiBgU0JiMRMjYeiIxYepodP25KWHqaVGFfYl4B2F9hZVsBBnWZtLSXeTheTSu+vpd4U2sBfG9PU2v+hGkAAAIAHv/3AroCFgAUACsAgwCyIwAAK7AfM7QPBAA3BCuwAzKyKwEAK7QqBAA3BCuxCRYyMgGwLC+wJtawKjKxDAXpsAwQsRIBK7EABemwABCxBwErsRoF6bAVMrEtASuxDCYRErApObASEbEKIzk5sAASsCE5sAcRsQkfOTmwGhKwFzkAsSoPERKzExohJiQXOTAxJRQWFzI+ATU0JyEGFRQWMz4BPQEzJRUjHgEVFA4CIyInBiMiJjU0NjcjNQGWLjQoNBJO/qdNMzo3LFQBIz4cIyQ8PSFgMC5iXmAhHT6ZIjUDNUgvgGVlgEljAzcg355GMHk2Rmg0GFpakGoohDNGAAAAAQAK/ygCIgIMACAAcQCyGgAAK7IAAQArsAQzsSAE6bANL7QSBABDBCsBsCEvsB3WtAMFACYEK7IdAwors0AdAAkrsxgDHQgrtAgFACYEK7ADELEVASuxCwXpsAUysSIBK7EVCBESsgQNDzk5OQCxIBoRErQIChYDGCQXOTAxEzIWFTczBwYVFDMVFCMiJzUWMzI2PQEmNQcjNzY1NCYjDIaUmWNnas+QDQ8RAyYexpRoOpRrYQIMVGO3fYFOcbptA0cBHidPGJazRrNjOCoAAAEACv/vAjoCGwAhAFAAshkAACuyFAAAK7EOBOmyBwEAK7IDAQArsR8E6QGwIi+wHNa0BgUAJgQrsxcGHAgrtAsFACYEK7EjASsAsR8OERK3AAsGEBEXHCEkFzkwMRM+ATMyFhU3MwcGFRQWMzI3Fw4BIyImNQcjNzY1NCYjIgcKD1oxO0+ZY2dqLSMvLDYSXTE9T5RoOpQlHi4rAbooOV9ltX2BTjxIPzMkNV5ms0azYzc+RgAAAAACADz/RgIgAhQAHgAuAGwAsg4AACuxHwTpsgYBACu0JwQANwQrsBsvsRQE6bAUELAXINYRsRgE6QGwLy+wHtaxEQXpsCoysBEQsSIBK7EJBemxMAErsSIRERKzDgYUGyQXObAJEbEXGDk5ALEfDhESsBA5sCcRsAk5MDETND4DMzIWFRQGBwYjIicVFBYzMjYzFSIGIyImNTcyNjU0LgIiDgIUHgI8HzBCPiFygj5EK0djNTQpLY8xJ50tRG3wPlweMTE0MTAdHC8xAQ49XzglDY93bG0mGUdSHjQVUhZsM1tcbDhRKRISKlJwUioSAAABAB7/9AGUAhIAHAA9ALIIAAArsAoztAMEADcEK7IIAAArsQUE6bITAQArsRoE6bIVAQArsRgE6QGwHS+wENaxAAXpsR4BKwAwMRMUFjMyNzMVIwYjIi4DNTQ2MzIXMxUjJiMiBnhRRyEcR1ITHyNAQTAegnAfE1JHHCFHUQEDVXAMUgQOJjtiPoyDBFIMcP//AAD/JgCrAtkQBgBNAAD//wAo/+kC6ALlEAYBYQAAAAEAHv/0AQICEgASAE4AsgEAACuxAATpsgkBACuxCgTptBANAQkNK7QQBAArBCsBsBMvsQMBK7QBBQAJBCuxCQ4yMrEUASuxAQMRErENEDk5ALENEBESsAM5MDElFSIRND4DMxUiBgczFSMeAQEC5AwgMVM0Q0YGj48GRkJOARIhQ0o5JUxWTEJKVgD//wAy//QBFgISEA8DbgE0AgbAAAABACj/6QJNAuUAHwBBALIaAAArsRME6bIYAAArsRUE6bIGAwArsQ0E6bIIAwArsQsE6QGwIC+wANaxEAXpsSEBKwCxCxURErEAEDk5MDETND4DMzIXMxUjJiMiBhUUFjMyNzMVIwYjIi4DKBEwR3lMNix2jyQwanuAbSggk4EpMkt3Ry8RAWQyYmpPNAxSDKKMiaEKUgozTmlgAP//AB7/6QJDAuUQDwNwAmsCzsAA//8AKP/pAk0C5RAnAHkBBABQEAYDcAAA//8AHv/pAkMC5RAmAHlkUBAGA3EAAAAA//8AUAAAAlsDhBAnGFgAvgAAEAYDiQAA//8AUAAAAlsDhBAmA4kAABADAGoAtAC4AAEAHv9sAtAC2QAbAGsAshQAACuwBDOyFwMAK7EWBOmwGTKwCi+0CwQAKwQrtBsSFBcNK7EbBOkBsBwvsBTWsRMF6bAaMrITFAors0ATGQkrshQTCiuzQBQWCSuwExCxDgErsQQF6bIOBAors0AOCgkrsR0BKwAwMQEyFhURFA4CKwE1MzI1ETQrAREjAyM1IRUjFQIrSlsgNTQeUmM5Qu5dAccB6sUBxldF/tYsPx0MQkIBSzn+jAKJUFDDAAAA//8AUAAAAjkDhBAnGFkA3AAAEgIDhwAAAAEAKP/pAp0C5QAgAHwAshIAACuxDATpsgwSCiuzQAwPCSuyHgMAK7EDBOmyAx4KK7NAAwAJK7QGCRIeDSuxBgTpAbAhL7AY1rEJBemwBjKyCRgKK7NACQgJK7AJELEPASuxEAXpsAAg1hGxIAXpsSIBK7EACRESsgwSHjk5OQCxBgkRErAYOTAxAS4BIyIGByEVIR4BMzI2NzMCISIuAzU0PgMzMhcCLxBeV154DAFs/pIGf2daYBFgIf71S3dHLxERMEd5TO4rAfdOToJzUn6TZWr+3zNOaWAxMmJqTzTuAAAA//8AMP/pAm0C5RACADYAAP//AGQAAADCAtkQAgAsAAD//wAHAAABIgOEECMAav/uALgQAgAsAwD//wAj/+kBvALZEAIALQAAAAIAHgAAA8kC2QAeACgAawCyAAAAK7ALM7EoBOmyAAAAK7QMBAA2BCuyFAMAK7ECBOm0FicAFA0rsRYE6QGwKS+wE9axBAXpsAIysAQQsQEBK7EnBemwFTKwJxCxIwErsRsF6bEqASuxBBMRErAGOQCxJwwRErAjOTAxIQMjMBcUDgQjNTI+BD0BIREzMhYdAQ4BIycyPgE1NCYrARUBzQHhAQQOHCxGLhklGA8IAgGdk3+NAXVhCTE+FE1AtQKHe0Nogl9ULF4hRE50ZUeo/sZ0WQJeclIrNB44RvsAAAAAAgBQAAADyQLZABMAHQBfALIAAAArsAMzsR0E6bIFAwArsAkztAcCAAUNK7AbM7EHBOmwCzIBsB4vsATWsQMF6bAGMrADELEAASuwCDKxHQXpsAoysB0QsRgBK7EQBemxHwErALECHRESsBg5MDEhESERIxEzESERMxEzMhYXFRQGIycyPgE1NCYrARUB3v7QXl0BMV2MfIUBd2AJMT4UTUCkAUz+tALZ/sUBO/7GdVoCXHJSKzQeOEb7AAABAB4AAALQAtkAEgBWALILAAArsAQzsg4DACuxDQTpsBAytBIJCw4NK7ESBOkBsBMvsAvWsQoF6bARMrIKCwors0AKEAkrsgsKCiuzQAsNCSuwChCxBQErsQQF6bEUASsAMDEBMhYVESMRNCsBESMDIzUhFSMVAitKW11C7l0BxwHqxQHGV0X+1gE7Of6MAolQUMP//wBQAAACbgOEECcYWQDwAAAQBgOOAAD//wBQAAACigOEECcYWADSAAASAgOMAAD//wAPAAACYAOEECMCewCdAKgSAgOXAAAAAQBQ/3kCggLZAAsASwCyBAAAK7AAM7EHBOmyBAcKK7NABAIJK7IFAwArsAkzAbAML7AE1rEHBemwBxCxAgErtAEFADEEK7ABELEIASuxCwXpsQ0BKwAwMSEVIzUjETMRIREzEQGRUPFeAXZeh4cC2f15Aof9JwD//wAPAAACiwLZEAIAJAAAAAIAUAAAAnAC2QAOABoASQCyBgAAK7EWBOmyBwMAK7EKBOm0CxUGBw0rsQsE6QGwGy+wBtaxFgXpsAoyshYGCiuzQBYJCSuwFhCxEAErsQAF6bEcASsAMDElFA4CIyERIRUhFTMgFQY0LgIrAREzMj4BAnAULVk9/rcB6f50tAEPXQsZOCfj4yc4GdokRkUrAtlS1NcaLiosG/7xGi0AAP//AFAAAAJwAtkQAgAlAAAAAQBQAAACOQLZAAUALACyAQAAK7ICAwArsQUE6QGwBi+wAdaxAAXpsgABCiuzQAAECSuxBwErADAxMyMRIRUhrV0B6f50AtlSAAAAAAIAIv95AwoC2QAHABYAcwCyEwAAK7EABOmyEwAAK7EIBOmwDjKwCBC0FQQACgQrsBAysgwDACuxAwTpAbAXL7AV1rQUBQAxBCuwFBCxDAErsQMF6bADELEBASuxDgXpsA4QsREBK7QQBQAxBCuxGAErsQwUERKwCDmwAxGwADkAMDElIREhFBYVEAc+AT0BIREzFSM1IRUjNQEGAUv++gHORSoBwltQ/bhQUgI1FWgd/tN2IPHZpf1x0YeH0QAA//8AUAAAAlsC2RAGACgAAAABAA8AAAOEAtkAEQA6ALICAAArsQ0QMzOyBAMAK7EHCjMzAbASL7AR1rAGMrEQBemwCDKxEwErALEEAhESswAGCQ8kFzkwMQkBIwkBMxMRMxETMwkBIwERIwGb/uJuAUX+5XTuXe50/uUBRXb+6l0BRP68AXcBYv7MATT+zAE0/p7+iQFE/rwAAQAo/+kCZQLlADEAhQCyJQAAK7EABOmyACUKK7NAACsJK7IYAwArsREE6bIRGAors0ARFQkrtAoJJRgNK7EKBOkBsDIvsCvWsS0F6bAVINYRsRQF6bAtELEFASuxHwXpsA4g1hGxGwXpsTMBK7EOFBEStAAJGB0lJBc5ALEJABESsB85sAoRsB05sBESsBs5MDElMj4CNTQmKwE1MzI2NTQmIyIGByM+ATMyFhUUBxYVFA4DIyIuAyczFRQeAgFOOE4lD2BDbFg/X1lKV14BWAGMfniLaYIPKD5nQSlLTjglAVgTK1U7GiopFy5UUlsuN0RNR2t3c2NsLTF9HTk9Lh4NIzdcPAUfNjQfAAEAUAAAAooC2QAJAEIAsgkAACuwBTOyAAMAK7ADMwGwCi+wCdaxAgXpsAIQsQYBK7EFBemxCwErsQYCERKxAwg5OQCxAAkRErECBzk5MDETMxEBMxEjEQEjUFgBfWVY/odpAtn9pQJb/ScCVv2qAP//AFAAAAKKA4QQIwJ7AMYAqBICA4wAAAABAFAAAAJuAtkACgAwALIBAAArsAgzsgIDACuwBTMBsAsvsAHWsQAF6bADMrEMASsAsQIBERKxBAo5OTAxMyMRMxEBMwkBIwGtXV0BMW/+pwF6fP67Atn+zgEy/qf+gAFNAAAAAQAe//YCTwLZABcASACyFwAAK7ILAAArtAwEADYEK7IUAwArsQEE6QGwGC+wFNaxAQXpsAEQsRcBK7EWBemxGQErsQEUERKwBjkAsQEMERKwBDkwMQEhFBYVFA4EIzUyPgQ9ASERIwHx/voBBA4cLEYuGSUYDwgCAcJeAocSUhdEaoRhVi1eIkZQdmdHqf0nAAAA//8AUAAAAv4C2RAGADAAAP//AFAAAAKBAtkQBgArAAD//wAo/+kC6ALlEAIAMgAAAAEAUAAAAoEC2QAHAC8AsgMAACuwBjOyBAMAK7EBBOkBsAgvsAPWsQIF6bACELEHASuxBgXpsQkBKwAwMQEhESMRIREjAiP+i14CMV4Ch/15Atn9JwAAAP//AFAAAAJeAtkQBgAzAAD//wAo/+kCnQLlEAIAJgAA//8AHgAAAloC2RACADcAAAABAA8AAAJgAtkABwAhALIBAAArsgMDACuwBjMBsAgvsQkBKwCxAwERErAFOTAxMyM3AzMbATPxcYHycbm4b/QB5f6FAXsAAAADACgAAAMlAtkAJAAwADwAawCyEgAAK7IjAwArtBUxEiMNK7AlM7EVBOmwEDK0ITISIw0rsDAzsSEE6bEAAjIyAbA9L7Ab1rE4BemwOBCxEgErsSIxMjKxEQXpsQAlMjKwERCxKwErsQgF6bE+ASsAsTIxERKxGwg5OTAxATAzMh4DFRQOBSMVIzUiLgU1ND4DOwE1MxEyPgM0LgMjAxEiDgMUHgMB1gomQ2NGMxsnPzZLLh9fHy5LNj8nGzNGY0MmCl8XMEg1Jyc1SDAXXxcwSDUnJzVIMAJ8Bx83akg2VzgoFAwCXl4CDBQoOFc2SGo3Hwdd/dcFFyVKZEolFwX+hgF6BRclSmRKJRcFAAAA//8ADwAAAoIC2RACADsAAAABAFD/eQLEAtkACwBRALIIAAArsQsE6bIICwors0AIBgkrsgkDACuwATMBsAwvsAjWsQsF6bALELEAASuxAwXpswYDAAgrtAUFADEEK7ENASsAsQsIERKxBAM5OTAxJREzETMVIzUhETMRAiNeQ1D93F5SAof9cdGHAtn9eQAAAAEAMgAAAhwC2QAOADkAsg4AACuyBQMAK7ALM7QBCQ4FDSuxAQTpAbAPL7AE1rEHBemwBxCxDgErsAoysQ0F6bEQASsAMDEBIyImNREzERQ7AREzESMBv+hNWF1M5F1dARNcQQEp/sU5AXT9JwAAAAABAFAAAALuAtkACwA/ALIFAAArsQgE6bAAMrIGAwArsQIKMzMBsAwvsAXWsQgF6bAIELEJASuxAAXpsAAQsQEBK7EEBemxDQErADAxJTMRMxEhETMRMxEzAc7CXv1iXsJeUgKH/ScC2f15AocAAAAAAQBQ/3kDMQLZAA8AYQCyAQAAK7EEBOmwCDKyAQQKK7NAAQ8JK7ICAwArsQYKMzMBsBAvsAHWsQQF6bAEELEFASuxCAXpsAgQsQkBK7EMBemzDwwJCCu0DgUAMQQrsREBKwCxBAERErEMDTk5MDEpAREzETMRMxEzETMRMxUjAuH9b17CXsJeQ1AC2f15Aof9eQKH/XHRAAACAB4AAAMlAtkADQAWAEkAsgAAACuxDgTpsgMDACuxAgTptAUWAAMNK7EFBOkBsBcvsADWsQ4F6bAEMrIADgors0AAAgkrsA4QsRIBK7EKBemxGAErADAxIREjNSERMzIWHQEUBiMnMzI2NTQmKwEBBecBRKWWiIJk3dRAUlFB1AKHUv7qeGYDY39SUj1AUAADAFAAAAMaAtkACgATABcAUwCyAQAAK7AVM7ELBOmyAgMAK7AUM7QEEwECDSuxBATpAbAYL7AB1rELBemwAzKwCxCxDwErsQgF6bAIELEWASuxFQXpsRkBKwCxEwsRErAIOTAxKQERMxEzMhYVFAYlMzI2NTQmKwEBESMRAYr+xl2lloiB/r7UQFJRQdQCbV4C2f7qeGZlgFJSPUBQAWj9JwLZAAIAUAAAAnAC2QALABQAOgCyBAAAK7EMBOmyBQMAK7QHFAQFDSuxBwTpAbAVL7AE1rEMBemwBjKwDBCxEAErsQAF6bEWASsAMDElFAYjIREzETMyFhUFMzI2NTQmKwECcIJk/sZdpZaI/j3UQFJRQdTiY38C2f7qeGaTUj1AUAAAAQAo/+kCnQLlACAAYQCyHgAAK7EDBOmyAx4KK7NAAyAJK7ISAwArsQwE6bIMEgors0AMEAkrtAgHHhINK7EIBOkBsCEvsCDWsQAF6bAAELAPINYRsRAF6bAQL7EPBemxIgErALEIBxESsBg5MDETHgEzMjY3ITUhLgEjIgYHIzYzMh4DFRQOAyMgA4gRYFpnfwf+kQFsDHheV14QXyvuTHlHMBERL0d3S/71IQEKamWTflJzgk1P7jRPamIyMWBpTjMBIQAAAAACAFD/6QO7AuUAEgAdAHwAsgkAACuyAwAAK7EYBOmyCgMAK7IQAwArsRME6bQMBwMQDSuxDATpAbAeL7AJ1rEIBemwCzKwCBCxBgErsA0ysRYF6bAWELEbASuxAAXpsR8BK7EWBhESsAU5sBsRsQMQOTkAsQcYERKwFjmwDBGxABs5ObATErAVOTAxARQGIyImJyMRIxEzETM+ATMyFiUiBhAWMzI2NTQmA7u7jpWxCHZeXXkQq42er/6zcnx9cnF+fAFhntrBov60Atn+xZew0X+i/uyioYeNowAAAgAPAAACXgLZAA0AFQBQALIKAAArsAUzsgMDACuxFATptAsRCgMNK7ELBOmwBzIBsBYvsADWsQ8F6bAPELEGASuwEjKxBQXpsRcBK7EPABESsAk5sAYRsQgLOTkAMDETNDYzIREjESMBIwEiJjYUFjsBNSMiPnZhAUldb/7rbgERZXFRPEfj40cCCV5y/ScBOv7GATpwkGJM+wD//wAe/+kCCwIbEAIARAAAAAIAHv/pAfgDBwAhACwA2gCyCAAAK7EnBOmyAgEAK7EiBOkBsC0vsAvWsSUF6bAlELEqASuxBQXpsBYg1hG0FwUAGwQrsS4BK7A2GroMIMEpABUrCg6wEBCwE8CxHxH5sBzAsBAQsxEQExMrsxIQExMrsB8Qsx0fHBMrsx4fHBMrshEQEyCKIIojBg4REjmwEjmyHR8cERI5sB45ALcQHxESExwdHi4uLi4uLi4uAbcQHxESExwdHi4uLi4uLi4usEAaAbElCxESsAA5sBYRswgCIickFzkAsSInERKxBQs5ObACEbAAOTAxEzYzMhYVFAYjIiY1ND4CNz4ENTMUDgUHDgEXIgYUFjMyNjU0Jm8sb3F9f25wfQ8kRjIOPykvGEoGFRMxJVMfKDqTRlBQRkVRTwHVRpWIgZSVhEyEgFULAwoJEBwTHSgeEBAIEgcKTj1tvm1tXGFuAAAAAAMAPAAAAcoCDAAIABEAHgAAATQmKwEVMzI2BxUzMjY1NCYjAzIWFRQHFhUUBisBEQFbLjtiYjsuy4wnLS4mBVJGRWBUR/MBeB0sjil1myomISoBJVA0VxwlWkFVAgwAAAEAPAAAAXICDAAFACwAsgUAACuyAAEAK7EDBOkBsAYvsAXWsQQF6bIEBQors0AEAgkrsQcBKwAwMRMhFSMRIzwBNuJUAgxM/kAAAAACABT/iAIyAgwADQATAHIAsgoAACuxDgTpsgoAACu0AAQAHwQrsAUysAAQtAwEAAsEK7AHMrIDAQArsREE6QGwFC+wDNa0CwUAGwQrsAsQsQMBK7QSBQA8BCuwEhCxDwErsQUF6bMIBQ8IK7QHBQAbBCuxFQErsRIDERKwDjkAMDE3PgE1IREzFSM1IRUjNTczESMVFE0wIgFTQEb+bkat3axABffQ/jS4eHi4DAF0O+AAAP//AB7/6QH3AhsQAgBIAAAAAQAKAAAC8wIMABEAPQCyDAAAK7EFCDMzsg4BACuxAAIzMwGwEi+wCdawEDK0CAUAPAQrsAAysRMBKwCxDgwRErMBBwoQJBc5MDEBFTczBwEjJxUjNQcjASczFzUBqMBr8gESauFT4WoBEvJrwAIMycn6/u7i4uLiARL6yckAAAABAB7/6QHHAhsAIwCaALIhAAArsQME6bIDIQors0ADIwkrshgBACuxEgTpshIYCiuzQBIVCSu0CwohGA0rsQsE6QGwJC+wI9axAAXpsBUg1hGxFAXpsAAQsQ8BK7EaBemyDxoKK7NADwoJK7APELAGINYRsR4F6bElASuxDxQRErMDFxghJBc5sRoGERKwHDkAsQoDERKwHjmwCxGwHDmwEhKwGjkwMTceATMyNjU0JisBNTMyNjU0JiMiByM+ATIWFRQHFhUUBiMiJ3YGNUU2QDsrSj4wMTwzZgNYAWK2bkFWdWPLBpwvNy0lHzZMNSEkK1RNVFdJSyUmVkxaswAAAQA8AAAB5wIMAAkARQCyCQAAK7AFM7IAAQArsAMzAbAKL7AJ1rECBemwAhCxBgErtAUFADwEK7ELASuxBgIRErEDCDk5ALEACRESsQIHOTkwMRMzERMzESMRAyM8VOtsU+ttAgz+YwGd/fQBnf5j//8APAAAAecCuxAiAnts3xICA6wAAAAAAAEAPAAAAdoCDAAKADMAsgkAACuwBTOyCgEAK7ACMwGwCy+wCda0CAUAPAQrsAAysQwBKwCxCgkRErEBBzk5MDETFTczBwEjJxUjEY/UYPsBEmrhUwIM1NT6/u7i4gIMAAEAFP/2AbUCDAAWADgAsgMAACuyDgAAK7EPBOmyAAEAK7EFBOkBsBcvsBbWtAUFADwEK7AFELEDASuxAgXpsRgBKwAwMRMhESMRIxUUDgUjNTI+BDViAVNUrAIIDRghMh8SHBALBAECDP30AcBiJTxOOz0oGVAZODljSD4AAAAAAQA8AAACGgIMAAwAQgCyDAAAK7AFM7IAAQArsAMzAbANL7AM1rELBemwCxCxBgErsQUF6bEOASuxBgsRErEBAzk5ALEADBESsQIHOTkwMRMzGwEzESMRAyMDESM8aIeHaFSCMoJUAgz+ugFG/fQBa/69AUP+lQAAAQA8AAAB3gIMAAsAPwCyCwAAK7AGM7IAAQArsAQztAIJCwANK7ECBOkBsAwvsAvWsQoF6bABMrAKELEHASuwAzKxBgXpsQ0BKwAwMRMzFTM1MxEjNSMVIzxU+lRU+lQCDNfX/fTp6f//AB7/6QH4AhsQAgBSAAAAAQA8AAAB3QIMAAcALwCyBwAAK7ACM7IAAQArsQUE6QGwCC+wB9axBgXpsAYQsQMBK7ECBemxCQErADAxEyERIxEjESM8AaFU+VQCDP30AcD+QAD//wA8/yYCEQIbEAYAUwAA//8AHv/pAdwCGxACAEYAAAABABQAAAGIAgwABwA6ALIFAAArsgABACuxBwTpsAIyAbAIL7AF1rEEBemyBAUKK7NABAIJK7IFBAors0AFBwkrsQkBKwAwMRMhFSMRIxEjFAF0kFSQAgxM/kABwAAAAP//AAr/JgHUAgwQAgBcAAAAAwAe/yYDMwKiABsAJgAyAJIAshEAACuwCDOxLQTpsCEyshEtCiuzQBENCSuyFwEAK7ACM7EnBOmwHDKyFycKK7NAFxoJKwGwMy+wFNaxKgXpsCoQsQ0BK7EZMDIytAwFADwEK7EAHjIysAwQsSQBK7EFBemxNAErsQ0qERKxERc5ObEkDBESsQIIOTkAsS0RERKwCzmwJxG0BQAOFBkkFzkwMQE2MzIWFRQGIyImJxEjEQ4BIyImNTQ2MzIXNTMXIgYUFjMyNjU0JiEiBhUUFjMyNjU0JgHQLWRmbG1kMT4jUx8/NWVna2VeMVODQENDQENGRv5kQ0JCQ0BDQgG9XpiGf5UjK/7vARYtJpCDhple5dVsvmxsXGBubV5fbGtdYW0A//8ACgAAAdICDBACAFsAAAABADz/iAIaAgwACwBRALIAAAArsQME6bIAAwors0AACgkrsgEBACuwBTMBsAwvsADWsQMF6bADELEEASuxBwXpswoHBAgrtAkFABsEK7ENASsAsQMAERKxBwg5OTAxMxEzETMRMxEzFSM1PFT5VD1GAgz+QAHA/jS4eAAAAQAyAAABrgIMAA8AOQCyCgAAK7IAAQArsAcztAwFCgANK7EMBOkBsBAvsA/WsQIF6bACELEKASuwBjKxCQXpsREBKwAwMRMzFRQWOwE1MxEjNSMiJjUyVCIYmlRUlztWAgzFGRn3/fTJQjkAAQA8AAACZAIMAAsAPwCyBQAAK7EIBOmwADKyBgEAK7ECCjMzAbAML7AF1rEIBemwCBCxCQErsQAF6bAAELEBASuxBAXpsQ0BKwAwMSUzETMRIREzETMRMwF6llT92FSWVEwBwP30Agz+QAHAAAAAAAEAPP+IAqACDAAPAGEAsgEAACuxBATpsAgysgEECiuzQAEPCSuyAgEAK7EGCjMzAbAQL7AB1rEEBemwBBCxBQErsQgF6bAIELEJASuxDAXpsw8MCQgrtA4FABsEK7ERASsAsQQBERKxDA05OTAxKQERMxEzETMRMxEzETMVIwJa/eJUllSWVDxGAgz+QAHA/kABwP40uAAAAgAUAAACaAIMAAwAFQBRALIAAAArsQ0E6bIDAQArsQIE6bQFFQADDSuxBQTpAbAWL7AA1rENBemwBDKyAA0KK7NAAAIJK7ANELERASuxCQXpsRcBKwCxFQ0RErAJOTAxMxEjNSEVMzIWFRQGIyczMjY1NCYrAcu3AQt2a2heSaJ8QjA4OnwBwEy3XFJJXkwvKTUwAAMAPAAAAmICDAALABQAGABWALIKAAArsBYzsQwE6bILAQArsBUztAEUCgsNK7EBBOkBsBkvsArWsQwF6bAAMrAMELEQASuxBgXpsAYQsRcBK7QWBQA8BCuxGgErALEUDBESsAY5MDETFTsBMhYVFAYrARETMzI2NTQmKwEBESMRkHEDbGleSfZUfEIwODp8AdJTAgy3W1NJXgIM/kAvKTUwAQP99AIMAAIAPAAAAdkCDAALABQAQgCyCgAAK7EMBOmyCwEAK7QBFAoLDSuxAQTpAbAVL7AK1rEMBemwADKwDBCxEAErsQYF6bEWASsAsRQMERKwBjkwMRMVOwEyFhUUBisBERMzMjY1NCYrAZBxA2xpXkn2VHxCMDg6fAIMt1tTSV4CDP5ALyk1MAAAAAABAB7/6QHcAhsAGwBeALIJAAArsQ8E6bIPCQors0APDAkrsgMBACuxGATpshgDCiuzQBgACSu0FBMJAw0rsRQE6QGwHC+wDNawADKxDQXpsBsysR0BK7ENDBESsQELOTkAsRQTERKwBjkwMRM+ATMyFhUUBiMiJiczFjMyNjcjNTMuASMiBgckB21ban99a15wCFQVa0FNBePgC0k6NEAIAVxcY5yCf5VrYH5eVE1JUDs3AAACADz/6QLHAhsAGAAjAHYAshUAACuyDAAAK7EeBOmyFgEAK7IGAQArsRkE6bQYEwwGDSuxGATpAbAkL7AV1rEUBemwFzKwFBCxEgErsAAysRwF6bAcELEhASuxCQXpsSUBK7EhHBESsQYMOTkAsRMeERKwHDmwGBGxCSE5ObAZErAbOTAxEzQ+AzMyFhUUBiMiLgM1IxUjETMVJSIGFBYzMjY1NCbwCiAxVzdxfX9uN1cyIQteVFQBSkZQUEZFUU8BNRIxRDgnlYiBlCY4SD4c6QIM15ltvm1tXGFuAAAAAAIACgAAAdUCDAAPABgAWwCyDAAAK7AHM7IFAQArsRUE6bQKEgwFDSuxCgTpAbAZL7AA1rEQBemwEBCxCAErsBMysQcF6bEaASuxEAARErALObAIEbEKDTk5ALESChESsA05sBURsAA5MDETND4COwERIzUjByM3LgE3FDsBNSMiBhVCDiFALPhURctnzUNSW1uJiSoxAXcYLzAe/fTa2t0GTD1Gmysk//8AHv/pAfcC5BAmA6kAABACAENyAAAA//8AHv/pAfcCzRAmA6kAABACAGp5AQAAAAEAEv9dAgUC2QAnAJMAsggAACuyDQMAK7IYAQArtAMEAEMEK7AhL7QkBAATBCu0CwoDDQ0rsBEztAsEAB8EK7APMgGwKC+wCNawDDK0BwUAPAQrsQ4SMjKyBwgKK7NABxEJK7IIBwors0AICgkrsAcQsScBK7QcBQA8BCuyJxwKK7NAJyMJK7EpASuxJwcRErEYITk5ALEDCBESsBM5MDEBNCYjIgYVESMRIzUzNTMVMxUjFT4DMzIWFREUDgIjIic1PgE1AbJCKkJLU1RUU6urDRIqOyNLWjdQUB4KBDV7AVw3MGJO/u0CVEBFRUCfEBQhEkpE/uw/a0AjASgCfFwAAAD//wA8AAABcgLkECIAdiMAEgIDpwAAAAAAAQAe/+kB3AIbABsAXgCyCgAAK7EEBOmyBAoKK7NABAcJK7IQAQArsRcE6bIXEAors0AXFAkrtBoBChANK7EaBOkBsBwvsAbWsBQysQcF6bATMrEdASuxBwYRErEIEjk5ALEaARESsA05MDElIx4BMzI3Mw4BIyImNTQ2MzIWFyMuASMiBgczAVfiBU1BaxVUCHBea31/alttB1QIQDQ6SQvf6FRefmBrlX+CnGJdNztQSQD//wAk/+kBzQIbEAIAVgIA//8ARgAAAJoC2RACAEwEAP////YAAAERAsUQIgBq3fkQAgDzFAAAAP//AAD/JgCrAtkQAgBNAAAAAgAUAAAC/gIMABYAHwBlALIPAAArsBYzsRkE6bAAMrIFAQArsREE6bQHGA8FDSuxBwTpAbAgL7AE1rQSBQA8BCuyBBIKK7NABBYJK7ASELEPASuxGQXpsAYysBkQsR0BK7ELBemxIQErALEYGRESsAs5MDE3Mj4BPQEhFTMyFhUUBisBESMVFA4BIyUjFTMyNjU0JhQfHxABU3Fta2FG9qwnQjgCHXx8OjgxUCyLjHnWQ1hFVgHAYYydNuqeHywrKAAAAAIAPAAAAycCDAASABsAYQCyAQAAK7AEM7EVBOmyBgEAK7AKM7QIAwEGDSuwEzOxCATpsAwyAbAcL7AF1rEEBemwBzKwBBCxAQErsAkysRUF6bALMrAVELEZASuxEAXpsR0BKwCxAxURErEQGTk5MDEhIzUjFSMRMxUzNTMVMzIWFRQGJyMVMzI2NTQmAoD2+lRU+lRxbWtia3x8Ozcy6ekCDNfX1kJYRVfqnh4uKSkAAQAUAAACBwLZAB0AfwCyCAAAK7AcM7INAwArshgBACu0AwQAQwQrtAsKAw0NK7ARM7QLBAAfBCuwDzIBsB4vsAjWsAwytAcFADwEK7EOEjIysgcICiuzQAcRCSuyCAcKK7NACAoJK7AHELEdASu0HAUAPAQrsR8BK7EdBxESsBg5ALEDCBESsBM5MDEBNCYjIgYVESMRIzUzNTMVMxUjFT4DMzIWFREjAbRCKkJLU1RUU6urDRIqOyNLWlMBXDcwYk7+7QJUQEVFQJ8QFCESSkT+gv//ADwAAAHaAuQQIgB2UgASAgOuAAAAAP//ADwAAAHnAuQQJgBDbgASAgOsAAAAAP//AAr/JgHUArsQIgJ7RN8QAgBcAAAAAAABADz/iAHeAgwACwBLALIEAAArsAAzsQcE6bIEBwors0AEAgkrsgUBACuwCTMBsAwvsATWsQcF6bAHELECASu0AQUAGwQrsAEQsQgBK7ELBemxDQErADAxIRUjNSMRMxEzETMRATBGrlT6VHh4Agz+QAHA/fQAAAABAA8AAAOZAtkAHgBbALIBAAArsBozsgQDACuwFDMBsB8vsATWsQUF6bAFELENASuxDgXpsA4QsRQBK7EVBemxIAErsQ0FERKxAQA5ObAOEbAdObAUErEaGzk5ALEEARESsQgdOTkwMSEjJgI1MxQSFz4DNTMUFhc2EjUzFA4CByMmJwYBMGZLcGRGRy0qNhVkQktQUmQpRUImZlszOH4Bgtm5/uqJVFeQl16065GVAQ+0b9++jUCY070AAAEACgAAAp4CDAAVAGQAsgEAACuwETOyAwEAK7AOMwGwFi+wA9a0BAUAPAQrsAQQsQkBK7QKBQA8BCuwChCxDgErtA8FADwEK7EXASuxCQQRErEAATk5sAoRsBQ5sA4SsRESOTkAsQMBERKxBhQ5OTAxMyMmETMUFz4BNTMUFzY1MxAHIyYnBvZejlJrMzFSa2RSh15DIyLhASvB73C5aaPv29X+4u5qd3kAAAACAB4AAAMHAtkACAAcAGYAshIAACuxAATpshcDACu0CQgSFw0rsQkE6bQVFBIXDSuwGzOxFQTpsBkyAbAdL7AS1rAWMrEABemxCRgyMrIAEgors0AAGwkrshIACiuzQBIUCSuwABCxBAErsQ4F6bEeASsAMDElMzI2NTQmKwE1MzIWHQEUBiMhESM1MzUzFTMVIwFE1EBSUUHUpZaIgmT+xsnJXc3NUlI9QFBSeGYDY38CI1JkZFIAAgAUAAACXgKIAAgAGwByALISAAArsQAE6bIVAQArsBkzsRQE6bAJMrIVFAors0AVFwkrtAgKEhcNK7EIBOkBsBwvsBLWsBYysQAF6bEJGDIysgASCiuzQAAbCSuyEgAKK7NAEhQJK7AAELEEASuxDgXpsR0BKwCxCAARErAOOTAxJTMyNjU0JisBNRUzMhYVFAYrAREjNTM1MxUzFQEVfEIwODp8dmtoXkn2ra1UsEwvKTUwt2tcUkleAcBMfHxMAAAAAAEAZP/pA4sC5QAnAJUAshsAACuyEgAAK7EMBOmyDBIKK7NADA8JK7IcAwArsiUDACuxAwTpsgMlCiuzQAMACSu0HhkSJQ0rsAgzsR4E6bAGMgGwKC+wG9axGgXpsB0ysBoQsRgBK7AfMrEJBemwBjKyCRgKK7NACQgJK7AJELEPASuxEAXpsAAg1hGxJwXpsSkBK7EACRESsgwSJTk5OQAwMQEuASMiBgchFSEeATMyNjczAiEiLgMnIxEjETMRMz4EMzIXAx0QXldeeAwBbP6SBn9nWmARYCH+9UhyRzEUAlVeXlcFGTRHbkPuKwH3Tk6Cc1J+k2Vq/t8uSGFcMP60Atn+xS9XWEEo7gABAEf/6QKgAhsAIgChALIQAAArsgoAACuxBATpsgQKCiuzQAQHCSuyEQEAK7IXAQArsR4E6bIeFwors0AeGwkrtBMOChcNK7AAM7ETBOmwITIBsCMvsBDWtA8FADwEK7ASMrAPELENASuwFDKxAQXpsCEysgENCiuzQAEACSuwARCxBgErsBsysQcF6bAaMrEkASuxAQ0RErAMObAGEbEKFzk5sAcSsQgZOTkAMDElIx4BMzI3Mw4BIyImJyMVIxEzFTM+ATMyFhcjLgEjIgYHMwIb4gVNQWsVVAhwXmZ8BkhTU0sOel5bbQdUCEA0OkkL3+hUXn5ga4l26AIM12t7Yl03O1BJAAACAA8AAAMCAtkACwAOAEAAsgsAACuxAgYzM7IAAwArtAkOCwANK7EJBOmwBDIBsA8vsAfWsQYF6bEQASuxBgcRErANOQCxAA4RErANOTAxATMBIycjFSM1IwcjAQsBAVJkAUxkZYdegWFjAgaTjQLZ/Sfb29vbASkBQP7AAAAAAAIACgAAAiMCDAALAA8AKACyCgAAK7EDBjMzsgABACsBsBAvsREBKwCxAAoRErMFCA0PJBc5MDETMxYTIycHIycHIzABJwcX8Vtcel5BSFs7PV4BTz9HPwIM4f7Vo6ORkQEMnamdAAAAAgBkAAAD8gLZAAIAFgBgALISAAArsgUJDTMzM7ITAwArsAMztBAVEhMNK7AAM7EQBOmxBwsyMgGwFy+wEtaxEQXpsBQysBEQsQoBK7EJBemxGAErsQoRERKxAwI5ObAJEbABOQCxExURErABOTAxAQsBEzMBIycjFSM1IwcjNyMVIxEzETMDBZONXWQBTGRlh16BYWNhnl5ewQEpAUD+wAGw/Sfb29vb29sC2f5QAAACAEcAAALhAgwAAwAWAFIAshIAACuyBwoNMzMzshMBACuwBDO0EBUSEw0rsRAE6QGwFy+wEta0EQUAPAQrsBQysRgBKwCxEBIRErIDCQw5OTmwFRGwAjmwExKxAAE5OTAxAScHFwMzFhMjJwcjJwcjNyMVIxEzETMCFz9HPyFbXHpeQUhbOz1eT31TU58BDJ2pnQGp4f7Vo6ORkbOzAgz+9QAAAAIADwAAA4QC2QALAA4APACyCgAAK7EDBjMzsgADACuxDATpAbAPL7AH1rEGBemxEAErsQYHERKwDTkAsQwKERK0AgUICw0kFzkwMRMhAwEjAREjEQEjAScXN6cCReMBe3b+6l3+4m4BezFzcQLZ/t3+SgFE/rwBRP68AbTTnJwAAgAKAAAC8wIMAAIADwBCALIOAAArsQcKMzOyAwEAK7AFM7EABOkBsBAvsAvWtAoFADwEK7ERASuxCgsRErABOQCxAA4RErQBBgkMDyQXOTAxARc3JTAhBwEjJxUjNQcjAQEdYmj+hgIu1gEuauFT4WoBLgHAbW1M3v7S4uLi4gEuAAAAAgBkAAAEVgLZAAIAFQBqALIRAAArsgYJDDMzM7IDAwArsBIzsQAE6bQUDxEDDSuxFATpAbAWL7AR1rEQBemwEzKwEBCxCgErsQkF6bEXASuxChARErIAAxU5OTmwCRGwATkAsQ8RERKxCAs5ObEAFBESsQEFOTkwMQEXNyUhAwEjAREjEQEjASERIxEzESECK3Nx/moCReMBe3b+6l3+4m4BNf6sXl4BmQKHnJxS/t3+SgFE/rwBRP68AWP+nQLZ/twAAAIARwAAA50CDAATABYAcQCyDwAAK7IEBwozMzOyAAEAK7ECEDMzsRQE6bQSDQ8ADSuxBgkzM7ESBOkBsBcvsA/WtA4FADwEK7ARMrAOELEIASu0BwUAPAQrsRgBK7EIDhESsgATFDk5ObAHEbAVOQCxEg0RErADObAUEbAVOTAxATAhBwEjJxUjNQcjNyMVIxEzFSEnFzcBFwIu1gEuauFT4Wrk/lNTAUYZYmgCDN7+0uLi4uLk5AIM3JBtbQAAAAEAIv9AAmUDJwBOAQUAskkAACuxGQTpskwAACu0FgQAKgQrsjYDACuxKgTpsjYqCiuzQDY0CSuwOTKwEC+wCzO0AwQANgQrsAkysA0g1hG0BgQANgQrtCIjSTQNK7EiBOkBsE8vsC7WsS0F6bAtELAAINYRsRMF6bATL7EABemwLRCxMwErtDQFABEEK7A0ELE5ASu0OgUAEQQrsAoysDoQsR4BK7FDBemwJyDWEbE/BemxUAErsTMtERKwFjmwNBGzEAMxTCQXObA5ErYGGQ0jKiJJJBc5sDoRsDw5sCcSsEE5ALFJBhESsQATOTmxIhYRErEeQzk5sCMRsEE5sCoSsi0uPzk5ObA2EbExPDk5MDEXFBYzMjYzMhYfARUmIyIGIyImNTQ2MzIWMzI+AjU0JisBNTMyNjU0JiMiBgcjPgE3JiczFjMyNjczBgceARUUBxYVFA4DIyImIyIGhCEbFE0jGE0ZGlk9Ik0bPF5TOxByHDhOJQ9gQ2xYP19ZSldeAVgBSUQaATsIVCgwAzsEGUJJaYIPKD5nQSRjCRgcMxYZCgUDAl4KCkVIQEsdGiopFy5UUlsuN0RNR01pGSE0QiIgNCEYZEdsLTF9HTk9Lh4PFgAAAAABACv/RgHHAl0APgD+ALI9AAArsRUE6bIBAAArsRIE6bIuAQArsSQE6bIkLgors0AkJgkrsi4kCiuzQC4sCSuwMTKwDS+xBgTpsAYQsAkg1hGxCgTptBwdPSwNK7EcBOkBsD8vsA/WsQMF6bAsMrAnINYRsSYF6bADELQrBQARBCuwKy+wAxCxGAErsToF6bAhINYRsTYF6bIhNgors0AhHAkrsCEQsDEg1hG0MgUAEQQrsUABK7EmKxESsCk5sTEDERK1Bg0SFSQ9JBc5sRghERKwNDmwMhGzCgkzOCQXOQCxPQkRErEDDzk5sRwSERKxGDo5ObAdEbA4ObAkErA2ObAuEbEpNDk5MDEWIgYVFBYzMjYzFSIGIyI1NDYzMhYzMjY1NCYrATUzMjY1NCYjIgcjNjcmJzMWMzI2NzMGBxYVFAcWFRQGIyK4GRUfKh5ZJiFdI50/MhRLEigwOytKPjAxPDNmA1gBSR8COwdVKDADOwUdU0FWZlMdCxYSGxkVUhaLNkUWLSUfNkw1ISQrVF8oIjpCIiA6IStcSyUmVktbAP//ADwAAAK+AtkQBgM7AAD//wA8/zgCfgIMEAYDWwAAAAMAKP/pAugC5QAKABEAFwBlALIDAAArsRYE6bIIAwArsQ4E6bQTEQMIDSu0EwQANwQrAbAYL7AG1rETBemwETKwExCxEgErsAsysQAF6bEZASuxEhMRErMIDBADJBc5ALETFhESsAU5sBERsAA5sA4SsAY5MDEBFAYjIiYQNjMyFgcuASMiBgcFIR4BMjYC6MCgnsLCnaDBXgiLcG2NBwID/f4Mi9SMAWGi1tMBVtPUkH2VlnxGdYuMAAAAAwAe/+kB+AIbAAoAEAAWAGUAsgYAACuxFQTpsgABACuxDgTptBIQBgANK7QSBAA3BCsBsBcvsAnWsRIF6bAQMrASELERASuwCzKxAwXpsRgBK7EREhESswANDwYkFzkAsRIVERKwCDmwEBGwAzmwDhKwCTkwMQEyFhUUBiMiJhA2BS4BIgYHBSEeATI2AQpxfX9ucH1+AQQITYBOBwEp/tgITnxOAhuViIGUlQEIlflSWltRRk5YWAAAAAABAA8AAALmAtkACQAnALIBAAArsgUDACuxAgczM7EJBOkBsAovsQsBKwCxCQERErAEOTAxISMBMxsBMDMVIwF5ZP76ZNbK04wC2f2XAmlSAAEACgAAAiYCDAAJACcAsgEAACuyBQEAK7ECBzMzsQkE6QGwCi+xCwErALEJARESsAQ5MDEhIwMzGwEwMxUjAR1buF6MlJ5dAgz+VwGpTAD//wAPAAAC5gOEECcYXQCMAAAQBgPoAAD//wAKAAACJgLZECMCsgHe//UQBgPpAAD//wAn/yYEiALlEGYDkgIAPChAABAHA7cCtAAA//8AHv8mA6YCHhAnA7cB0gAAEEYDsgIDPChAAAACACj/6QM4AuUAFAAlAHIAshQAACu0FgQADwQrsggDACu0IAQADwQrAbAmL7AE1rEkBemwJBCxFAErsgcVIDIyMrQTBQA6BCuyCRceMjIysBMQsRsBK7EPBemxJwErALEWFBESsRUYOTmwIBGzDxsjJCQXObAIErMHCh4hJBc5MDEhLgI0PgE3NTMVHgMVFAYHFSM9ATMVPgE1NCYnFSM1DgEUFgF8X5hdXZhfaEh7XDXAlGhoao2LbGhqjYwLWZ7Kn1gLFxcIOFuDT47CERdqHBwRj3B1khEcHBGR5JEAAAIAHv/pAjQCHAAQACIAdgCyCwAAK7QYBAARBCuyAQEAK7QiBAARBCsBsCMvsA/WsRQF6bAUELELASuyABEXMjIytAoFADoEK7ICGSAyMjKwChCxHQErsQYF6bEkASsAsRgLERKzCQwXGiQXObAiEbQODwYUHSQXObABErMAAxEgJBc5MDETNTMVHgEVFAYHFSM1LgE0NhcOARUUFhc1MxU+ATU0JicVI/VoYnV3YGhhdnZhOUdHOWg5R0c5aAIDGRkOhHNtgg4YGA6D4INBD1pJSVoPFRUPWUdLWw8UAAD//wAPAAADmQPUECcD+AJ7AHwQJwP5AyoA6xAGA9QAAP//AAoAAAKpAyAQJwP4Afr/yBAnA/kCqQA3EAYD1QAA//8ADwAAA5kDhBAnFNACwQCqEAYD1AAA//8ACgAAAp4C2RAnFNACQf//EAYD1QAAAAEAFP8kAcACEQATAaEAshEBACuwEjMBsBQvsRUBK7A2Grr2GsDFABUrCg6wChCwBcCxCwz5sATAuj0F7LEAFSsKBbARLg6wCMAFsRII+Q6wB8C69hrAxQAVKwoOsA4QsAHAsQ8M+bAAwLAOELMCDgETK7EOAQiwBxCzAgcSEyu6PQXssQAVKwuzAwcSEyuxBxIIsAsQswMLBBMruj0F7LEAFSsLsAcQswYHEhMrsQcSCLAKELMGCgUTK7o9BeyxABUrC7AIELMJCBETK7EIEQiwChCzCQoFEyu6PQXssQAVKwuwCBCzDAgREyuxCBEIsAsQswwLBBMruvXtwMwAFSsLsA4Qsw0OARMrsQ4BCLAIELMNCBETK7r2GsDFABUrC7APELMQDwATK7EPAAiwCBCzEAgREyu69hrAxQAVKwuwDxCzEw8AEyuxDwAIsAcQsxMHEhMrAEASAAECAwQFBgcICQoLDA0ODxATLi4uLi4uLi4uLi4uLi4uLi4uAUAUAAECAwQFBgcICQoLDA0ODxAREhMuLi4uLi4uLi4uLi4uLi4uLi4uLrBAGgEAMDEBFScHFxUnByM3JzUXNyc1FzczBwHAnECJnTg3O4icP4icSzdNAQhDGckVQxmyuhZCGMgWQhjr9AAAAf6EAmP/7AMfAAsATwCyAwMAK7QKBAAfBCuzDgMBDiu0AAQADgQrsAoQsw4KCA4rtAUEAA4EKwGwDC+wANa0CwUAGwQrsAIysAsQsQgBK7AEMrQHBQAbBCsAMDEBNTMVMzUzFSM1IxX+hEjYSEjYAmOSGUOSGEL///7+AlUAKwLcEAYCtDwA////BwJg/6oCuBCHArf8xgHkAADAAEAAAAAAAP///wwCZv+wAr8QhwK2AfADNAAAQADAAAAAAAAAAf3XAkMAAALpABIANgCwDi+wBDO0DQQAHwQrsAAvsQgE6QGwEy+wBda0BAUAGwQrALENDhESsBE5sQgAERKwCzkwMQEiDgEVIzQ2MzIeAjMVIi4C/n0fJyBAW1FKf0ZOIChOPn4ClwknJEldISkhOxogGv///RD/hgENA1kQJhTOAAAQJxTOAUT/eRAnFM7+uv95ECcUzgHN/jMQJxTOAUb87hAnFM4AAPxmECcUzv67/O0QBxTO/jP+MwAI/P3/EwFVA2sACgAVACIALwA8AEkAVABfAXUAsjcAACuwOSDWEbQ0BAATBCuyGQAAK7IhAAArsjsAACuwBS+0BgQAEwQrsAovsQAE6bBML7FVWjMztFMEABMEK7BeL7RXBAATBCuxSk8yMrBGL7RBBAATBCuwDC+xFATpsBEvtBAEABMEKwGwYC+wT9a0UAUAEQQrsFAQsVMBK7RLBQAbBCuwSxCxJwErtCwFABEEK7AsELENASuxAAUyMrQUBQARBCuwFBCxCQsrtAIFABEEK7ELEDIysAIQsR8BK7QaBQARBCuwGhCxVQErtF8FABsEK7BfELFbASu0WgUAEQQrsUtTERKxNzY5ObAsEbMpNDk8JBc5sA0StiMkKi4wMTskFzmxHwIRErYWFx0hPT5IJBc5sBoRsxxBRkkkFzmxX1URErFEQzk5ALEAChESsRwdOTmwORGzGh8iNiQXObFMNxESsxYXMDEkFzmxRlcRErYjLiQ+REg9JBc5sEERsywnQy8kFzmwFBKxKSo5OTAxBTMVFAYjNTI2NSMTIzU0NjMVIgYVMxM3FxYVFAcnNjU0JwcBBycmNTQ3FwYVFBc3AxcHBiMiJzcWMzI3JwEnNzYzMhcHJiMiBxcFFSMiJjUzFBYzNQU1MzIWFSM0JiMV/vxYLykZFC1ZWC8pGRQtyT8zHx0eEhMg/eA/Mx8dHhITIAs+NB4iIB0dEg4OEyACoD40HiIgHR0SDg4TH/0OSSsvKhUaA1xJKy8qFRpKSSsvKhUaA1xJKy8qFRr8+D40HiIgHR0SDg4THwKePjQeIiAdHRIODhMf/aE/Mx8dHhITIAIhPzMfHR4SEyD+WC8pGRQtWlgvKRkULQAAAgBQ/3kCzQOEAAwAGgCUALIaAAArsBYzsg0DACuwEDOwCS+0AwQAKwQrsgMJCiuzQAMACSuwBjIBsBsvsBrWsQ8F6bAPELEAASu0AQUAEQQrsAEQsQYBK7QHBQARBCuwBxCxFwErsRIF6bMVEhcIK7QUBQAxBCuxHAErsQAPERKwGTmxBgERErAJObEXBxESsBA5ALENGhESsw8SExgkFzkwMRMzFjMyNjczBiMiLgEHMxEBMxEzFSM1IxEBI9Y7B1UoMAM7C40kPDSHWAF9ZUNQS/6HaQOEQiIghxNAd/2lAlv9cdGHAlb9qgACADz/iAIjArsADQAaAJsAsg0AACuwCTOyAAEAK7ADM7AXL7QRBAArBCuyERcKK7NAEQ4JK7AUMgGwGy+wDdaxAgXpsw4CDQgrtA8FABEEK7ACELEKASu0BQUAPAQrsxUFCggrtBQFABEEK7AUL7QVBQARBCuzCAUKCCu0BwUAGwQrsRwBK7EPAhESsAw5sBQRsBc5sAoSsAM5ALEADRESswIFBgskFzkwMRMzERMzETMVIzUjEQMjEzMWMzI2NzMGIyIuATxU62w8RknrbT87CFQoMAM7C40kPDQCDP5jAZ3+NLh4AZ3+YwK7QiIghxNAAAAAAgAUAAACjQLZAAkAGwBnALIOAAArsQUE6bITAwArshABACuwFzO0EQQANwQrsBUytBkEDhENK7EZBOkBsBwvsA7WsBIysQUF6bEUGDIysgUOCiuzQAUXCSuyDgUKK7NADhAJK7AFELEAASuxCgXpsR0BKwAwMSU0JisBFTMyPgE3FAYjIREjNTM1MxUzFSMVMzICMDxH4+MxPhRddmH+t1lZXVxctPbPMU37KzQfXnICG0Z4eEZ8AAIACgAAAeoCDAAHABoAcQCyDAAAK7EEBOmyEQEAK7QXAwwRDSuxFwTptA8ODBENK7AVM7QPBAA3BCuwEzIBsBsvsAzWsBAysQQF6bESFjIysgQMCiuzQAQVCSuyDAQKK7NADA4JK7AEELEAASuxCAXpsRwBKwCxAwQRErAIOTAxJTQrARUzMjY3FAYjIREjNTM1MxUzFSMVMzIWAY9bmJgpMltVRv75Pj5USEh2cGiZTpsqIENTAX5GSEhGS0wAAAIAUAAAAl4C2QAMABsAZQCyEgAAK7ITAwArsQYE6bQQBxITDSuxEATpAbAcL7AS1rERBemwBjKwERCxAgErsRcF6bAaMrEdASuxAhERErANObAXEbEZGzk5ALEQEhESsRobOTmwBxGxDRk5ObAGErAXOTAxATY1NCYrAREzMjcnNxcGKwERIxEhMhYVFAcXBwHeH0tDwsIYFzYyTCQw5V0BLWx1PDoyAbAhNjxE/wAFNjKvEP7LAtlvZ184OjIAAAIAPP8mAhICGwAOACEAeACyFAAAK7EKBOmyFAoKK7NAFBgJK7IQAAArshkBACuyHQEAK7EFBOkBsCIvsBjWsRcF6bAHMrQbBQAmBCuwFxCxAgErsSAF6bAQMrEjASuxAhcRErESHTk5sCARsQ8ROTkAsQoUERKyDxIWOTk5sAURsRsgOTkwMSU2NTQmIyIGFBYzMjcnNx8BBycGIyInESMRMxU2MzIWFRQBlCZTRUJQUEIhHEAxgz8xQy8+YUBUTTtsaHlzN1VecG+4bw5AMoM/MkMdTv7vAuZPXpqEfwAAAQBQAAACOQM5AAcANgCyAQAAK7ICAwArsQcE6bAHELQEBAAMBCsBsAgvsAHWsQAF6bAAELEDASuxBgXpsQkBKwAwMTMjESE1MxUhrV0BjF3+dALZYLIAAAEAPAAAAWMCdQAHADcAsgcAACuyAAEAK7EFBOmyAAUKK7NAAAIJKwGwCC+wB9axBgXpsAYQsQEBK7EEBemxCQErADAxEzM1MxUjESM801TTVAIMabX+QAABABQAAAJIAtkADQBXALIFAAArsgoDACuxDQTptAgHBQoNK7ACM7QIBAA3BCuwADIBsA4vsAXWsAkysQQF6bAAMrIEBQors0AEAgkrs0AEDAkrsgUECiuzQAUHCSuxDwErADAxEzMVIxEjESM1MzUhFSG8ampdS0sB6f50Ae1G/lkBp0bsUgAAAQAUAAABiAIMAA0AVwCyCgAAK7IBAQArsQQE6bQNDAoBDSuwBzO0DQQANwQrsAUyAbAOL7AK1rAAMrEJBemwBDKyCQoKK7NACQMJK7NACQcJK7IKCQors0AKDAkrsQ8BKwAwMRM1IRUjFTMVIxEjESM1UgE24kREVD4BSMRMeEb+/gECRgAAAAEAUP9SAjkC2QAZAFcAsgEAACuyAgMAK7EFBOmwDy+xEATptAYZAQINK7EGBOkBsBovsAHWsQAF6bAFMrAAELEUASuxCwXpsgsUCiuzQAsECSuyFAsKK7NAFA8JK7EbASsAMDEzIxEhFSEVMzIWFREUBisBNTMyNjURNCYrAa1dAen+dKxcXV1cNDArNTUrqALZUrJmWv79WmZSLy0BJy0vAAAAAQA8/3EBoQIMABwAcwCyDAAAK7AYM7INAQArsRAE6bAcL7QABABDBCu0FAcMDQ0rtBQEAEMEKwGwHS+wDNaxCwXpsBAysgsMCiuzQAsPCSuwCxCxAwErtBgFADwEK7IDGAors0ADHAkrsR4BK7EDCxESsBQ5ALEHDBESsBE5MDEXMjY9ATQmIyIGHQEjESEVIxU+ATMyFh0BFAYrAeIpQyQqPTNUASfTEEE5ST5ZTBpGMDeNOS5bVmQCDEy5MCdJRs9CTQAAAAABAA//eQOEAtkAFQBcALILAAArsQQHMzOyDQMAK7EQEzMzAbAWL7AI1rAPMrEHBemwETKwBxCxAwErtAIFADEEK7EXASuxAwcRErETFTk5sAIRsQAUOTkAsQ0LERK1AQAGCQ8SJBc5MDElMxUjNSMBESMRASMJATMTETMREzMBA0RAUB7+4l3+4m4BRf7heO5d7nj+4UrRhwFE/rwBRP68AXcBYv7MATT+zAE0/p4AAAEACv+IAy8CDAAVAF8AsgsAACuxBAczM7INAQArsRATMzMBsBYvsAjWsA8ytAcFADwEK7ARMrAHELEDASu0AgUAGwQrsRcBK7EDBxESsgATFTk5ObACEbAUOQCxDQsRErUBAAYJDxIkFzkwMSUzFSM1IyUVIzUFIwkBMxc1MxU3MwEC5UpGIf7+U/7+ZwEw/vBr3lPea/7wQLh42NjY2AEIAQTe3t7e/vwAAAABACj/MwJlAuUAOgCeALI0AwArsS0E6bItNAors0AtMQkrsAgvtA0EABMEK7AlL7EmBOkBsDsvsBXWsRcF6bAxINYRsTAF6bAXELEPASu0BQUAGwQrsAUQsSEBK7EABemwKiDWEbE3BemxPAErsQ8wERK3CAoSHCUmLTQkFzmwBRGwAzmwKhKwOTkAsQ0IERKwCjmwJRGyAAULOTk5sCYSsDk5sC0RsDc5MDElFAYHFhUUBiMiJzUWMzI1NCYnLgEnMxUUHgIzMj4CNTQmKwE1MzI2NTQmIyIGByM+ATMyFhUUBxYCZYB2Nkw4HDAaJUgZIXWEAVgTK1U7OE4lD2BDbFg/X1lKV14BWAGMfniLaYLIXHgKIjcqNAotCjYaJRUKgHQFHzY0HxoqKRcuVFJbLjdETUdrd3NjbC0xAAAAAAEAHv8zAccCGwAyAL4AshgBACuxEgTpshIYCiuzQBIVCSuwJi+0KwQAEwQrsAovsQsE6QGwMy+wMtaxAAXpsBUg1hGxFAXpsAAQsS0BK7QjBQAbBCuwIxCxDwErsRoF6bIPGgors0APCgkrsA8QsAYg1hGxHgXpsTQBK7EVMhESsDE5sRQAERKxKCk5ObAtEbUDEhcmKzAkFzmwIxKxGCE5ObEaBhESsBw5ALErJhESsCg5sAoRsh4jKTk5ObALErAcObASEbAaOTAxNx4BMzI2NTQmKwE1MzI2NTQmIyIHIz4BMhYVFAcWFRQGBxYVFAYjIic1FjMyNTQmJyYndgY1RTZAOytKPjAxPDNmA1gBYrZuQVZfUzZMOBwwGiVIGiGjBpwvNy0lHzZMNSEkK1RNVFdJSyUmVkRYCCU1KjQKLQo2GiYVD6IAAAAAAQBQ/3kCbgLZAA4AUwCyCAAAK7AEM7IJAwArsAwzAbAPL7AI1rEHBemwCjKwBxCxAwErtAIFADEEK7EQASuxAwcRErEMDjk5sAIRsQANOTkAsQkIERKzAQAGCyQXOTAxJTMVIzUjAREjETMRATMBAiVJUCz+u11dATFv/qdK0YcBTf6zAtn+zgEy/qcAAAAAAQA8/4gB2gIMAA4AVgCyCAAAK7AEM7IJAQArsAwzAbAPL7AI1rQHBQA8BCuwCjKwBxCxAwErtAIFABsEK7EQASuxAwcRErEMDjk5sAIRsQANOTkAsQkIERKzAQAGCyQXOTAxJTMVIzUjJxUjETMVNzMHAZpARiThU1PUYPtAuHji4gIM1NT6AAEAUAAAApkC2QATAEYAsgMAACuwDzOyBAMAK7ALMwGwFC+wA9axAgXpsAUysAIQsRMBK7AHMrQSBQAbBCuxCQ0yMrEVASsAsQQDERKxAQY5OTAxEycRIxEzETc1MxU3MwEVASMlFSPdMF1dMEb1eP6TAXZ0/v5GARsp/rwC2f7FKolN1f7GUv6z3j8AAQA8AAAB+AIMABMASQCyAwAAK7APM7IEAQArsAszAbAUL7AD1rQCBQA8BCuwBTKwAhCxEwErsAcytBIFABsEK7EJDTIysRUBKwCxBAMRErEBBjk5MDE3JxUjETMVNzUzFTczBxUXIycVI8AxU1MxRmdr0vJni0avKdgCDN4xayVnyXHSdCoAAAEACgAAAqIC2QASAGEAsgwAACuwCDOyEQMAK7AFM7QPDgwRDSuwAjO0DwQANwQrsAAyAbATL7AM1rAQMrELBemxAAMyMrILDAors0ALAgkrsgwLCiuzQAwOCSuxFAErALEODBESsgQHCjk5OTAxEzMVIxUBMwkBIwERIxEjNTM1M7xgYAFreP5kAZ9u/ohdVVVdAm9GiwE7/p7+iQFE/rwCKUZqAAAAAAEACgAAAgICDAASAGQAsg8AACuwCzOyAQEAK7AIM7QSEQ8BDSuwBTO0EgQANwQrsAMyAbATL7AP1rAAMrQOBQA8BCuxAgYyMrIODwors0AOBQkrsg8OCiuzQA8RCSuxFAErALERDxESsgcKDTk5OTAxEzUzFTMVIxU3MwkBIyUVIxEjNUZTR0fea/7wATBn/v5TPAHeLi5Gat7+/P742NgBmEYAAQAUAAADPgLZAAwAQQCyDAAAK7AIM7ICAwArsAUzsQEE6QGwDS+wDNaxCwXpsAMysgwLCiuzQAwBCSuxDgErALEBDBESsgQHCjk5OTAxEyM1IREBMwkBIwERI/vnAUQBa3j+ZAGfbv6IXQKHUv7FATv+nv6JAUT+vAAAAAEAFAAAAogCDAAMAEQAsgwAACuwCDOyAgEAK7AFM7EBBOkBsA0vsAzWtAsFADwEK7ADMrIMCwors0AMAQkrsQ4BKwCxAQwRErIEBwo5OTkwMRMjNSEVNzMJASMlFSPMuAEL3mv+8AEwZ/7+UwHATN7e/vz++NjYAAEAUP95AsQC2QAPAGEAsgkAACuwBDOyCgMAK7AOM7QMBwkKDSuxDATpsgcMCiuzQAcDCSsBsBAvsAnWsQgF6bALMrAIELEFASuwDTKxAAXpswMABQgrtAIFADEEK7ERASsAsQcJERKxAQA5OTAxJTMVIzUjESERIxEzESERMwKBQ1BR/oteXQF2XkrRhwFM/rQC2f7FATsAAQA8/4gCGgIMAA8AYQCyCQAAK7AEM7IKAQArsA4ztAwHCQoNK7EMBOmyBwwKK7NABwMJKwGwEC+wCdaxCAXpsAsysAgQsQUBK7ANMrEABemzAwAFCCu0AgUAGwQrsREBKwCxBwkRErEBADk5MDElMxUjNSM1IxUjETMVMzUzAd48Rkr6VFT6VEC4eOnpAgzX1wAAAAEAUAAAA8UC2QANAE4AsgUAACuwADOyCgMAK7AGM7ENBOm0CAMFCg0rsQgE6QGwDi+wBdaxBAXpsAcysAQQsQIBK7AJMrENBemyDQIKK7NADQwJK7EPASsAMDEhIxEhESMRMxEhESEVIQKBXv6LXl0BdgGi/rwBTP60Atn+xQE7UgAAAAEAPAAAArECDAANAE4AsgUAACuwADOyCgEAK7AGM7ENBOm0CAMFCg0rsQgE6QGwDi+wBdaxBAXpsAcysAQQsQIBK7AJMrENBemyDQIKK7NADQwJK7EPASsAMDEhIzUjFSMRMxUzNSEVIwHeVPpUVPoBJ9Pp6QIM19dMAAABAFD/UgPmAtkAGwBaALIaAAArsBUzshsDACuxGATpsAovsQsE6bQBFBobDSuxAQTpAbAcL7Aa1rEZBemwGRCxFgErsRUF6bAAMrAVELEPASuxBgXpsg8GCiuzQA8KCSuxHQErADAxAREzMhYVERQGKwE1MzI2NRE0JisBESMRIREjEQKBrFxdXVw0MCs1NSuoXv6LXgLZ/vxmWv79WmZSLy0BJy0v/n0Ch/15AtkAAAEAPP9xAu4CDAAeAHUAshAAACuxCxozM7IRAQArsQ4E6bAeL7QABABDBCu0FgcQEQ0rtBYEAEMEKwGwHy+wENaxDwXpsA8QsQwBK7ELBemwEjKwCxCxAwErtBoFADwEK7IDGgors0ADHgkrsSABK7EDCxESsBY5ALEHEBESsBM5MDEFMjY9ATQmIyIGHQEjESMRIxEhET4BMzIWHQEUBisBAi8pQyQqPTNU+VQBoRBBOUk+WUwaRjA3jTkuW1ZkAcD+QAIM/vswJ0lGz0JNAAACACj/6QMUAuUAMgA/AIwAsgAAACuwLzOxDwTpsB8ysggDACuxCQTptBk4AAgNK7EZBOkBsEAvsAPWsQwF6bIMAwors0AMCAkrsAwQsRQBK7E9BemwPRCxNQErsRwF6bFBASuxPRQRErEPADk5sDURtREZHh8vMSQXObAcErEgJTk5ALEPABESsDE5sDgRtgwDFBwpKjMkFzkwMQUiJjU0PgIzFSIGFRQWMzI3LgE1ND4CMzIWFRQHFjI+BzUXDgMjIicGNzY1NCYjIg4CFRQWAVuFriNLil5+e21tGgwxOjFKRB1fY3oGHBgUDg8HDAIMSgUXLVQ3NDE/THM2LxQlKxs/F8acUIt5RlKhjIWmAjCDSFqFQh2gdbxpAQIHBQ0FEgMVASgQISoaGBh3S7duVBAtZks4eQACAB7/6QJoAhsAJQAuAHwAsgAAACuwIjOxDQTpsBwysgYBACuxBwTptBUqAAYNK7EVBOkBsC8vsAPWsQoF6bAKELESASuxLQXpsC0QsSgBK7EYBemxMAErsS0SERK0AAcNBhAkFzmwKBGxJBU5ObAYErIaHCI5OTkAsSoNERK2CgMSGB4fJiQXOTAxBSImNTQ2MxUiBhUUFjMyNjMmNTQ2MzIWFRQHFjMyNxcOASMiJwY3NjU0IyIGFRQBCHZ0jn1LaUZMAgsDP1s0QVM8ChA7GjoKS0E2Li0pOjcaJBeTiHifTV5mdWEBRGVnamVPf0cBQyQmRBISaCtodkE5ZAAAAQAo/zMCnQLlACwAegCyGQMAK7EfBOmyHxkKK7NAHxwJK7ADL7QIBAATBCsBsC0vsBPWsSIF6bAiELEKASu0AAUAGwQrsAAQsSgBK7EpBemwHCDWEbEbBemxLgErsQoiERK1AwUNGR8lJBc5sAARsCs5ALEIAxESsAU5sB8RsgAGEzk5OTAxBRQGIyInNRYzMjU0JicuBDU0PgMzMhcjLgEjIgYVFBYzMjY3MwIHFgHJTDgcMBolSBohSG06JAoRMEd5TO4rXxBeV2p7gG1aYBFgIOk1byo0Ci0KNhomFQdDVWxMIjJiak807k5OooyJoWVq/vISJAABAB7/MwHcAhsAJwCBALITAQArsRoE6bIaEwors0AaFwkrsAMvtAgEABMEKwGwKC+wENaxHQXpsB0QsQoBK7QABQAbBCuwABCxIgErsBcysSMF6bAWMrEpASuxCh0RErUDBQ0TGiAkFzmwABGwJjmxIyIRErEVJDk5ALEIAxESsAU5sBoRsgAGEDk5OTAxBRQGIyInNRYzMjU0JicuATU0NjMyFhcjLgEjIgYVFBYzMjczDgEHFgFiTDgcMBolSBojWGZ/alttB1QIQDRETU5FaxVUB1xON28qNAotCjYbJhUPkXGCnGJdNztvYl1qflZoCyQAAQAe/3kCWgLZAAsATQCyCAMAK7EHBOmwCjKyBwgKK7NABwMJKwGwDC+wBdaxAAXpsgUACiuzQAUHCSuzAwAFCCu0AgUAMQQrsgIDCiuzQAIKCSuxDQErADAxJTMVIzUjESM1IRUjAWtDUFDwAjzvStGHAodSUgAAAQAU/4gBiAIMAAsATQCyCAEAK7EHBOmwCjKyBwgKK7NABwMJKwGwDC+wBdaxAAXpsgUACiuzQAUHCSuzAwAFCCu0AgUAGwQrsgIDCiuzQAIKCSuxDQErADAxNzMVIzUjESM1IRUj+DxGSpABdJBAuHgBwExMAAAAAQAPAAAClwLZAAgAMACyAgAAK7IEAwArsAczAbAJL7AC1rEBBemxCgErsQECERKwBjkAsQQCERKwBjkwMQERIxEBMxsBMwGFXf7nc9bQbwEe/uIBHgG7/p0BYwABAAr/OAJCAgwACAAjALIEAQArsAczAbAJL7AC1rEBBemxCgErsQECERKwBjkAMDElESMRAzMbATMBWF3xc66ob1b+4gEeAbb+ogFeAAAAAAEADwAAApcC2QAQAGAAshAAACuyBQMAK7AIM7QBAhAFDSuwCzO0AQQANwQrsA0yAbARL7AQ1rADMrEPBemwCjKyDxAKK7NADw0JK7IQDwors0AQAQkrsRIBK7EPEBESsAc5ALEFAhESsAc5MDElIzUzNQEzGwEzARUzFSMVIwEo3Nz+53PW0G/+7tzcXb5GGgG7/p0BY/5FGka+AAEACv84AkICDAAOAFcAsgoBACuwDTOwBy+wAjO0CAQANwQrsAAyAbAPL7AF1rAJMrEEBemwADKyBAUKK7NABAIJK7IFBAors0AFBwkrsRABK7EEBRESsAw5ALEKCBESsAw5MDElMxUjFSM1IzUzAzMbATMBWNzcXdzc8XOuqG9WRtjYRgG2/qIBXgAAAQAP/3kCggLZAA8APQCyCAAAK7AEM7IKAwArsA0zAbAQL7AD1rQCBQAxBCuxEQErsQIDERKxAA45OQCxCggRErMBAAYMJBc5MDElMxUjNSMLASMBAzMbATMDAk8zUCPHyHEBAvJxu7xv9krRhwEw/tABdgFj/uIBHv6dAAEACv+IAdICDAAPAD0AsggAACuwBDOyCgEAK7ANMwGwEC+wA9a0AgUAGwQrsREBK7ECAxESsQAOOTkAsQoIERKzAQAGDCQXOTAxJTMVIzUjJwcjEwMzFzczBwGnK0Ybg4Vfua9ffn5esEC4eMnJAQsBAb6+/QAAAAEAHv95A5EC2QAPAGQAsgoAACuxAQTpsg0DACuwAzOxDATpsAAyAbAQL7AK1rEBBemyAQoKK7NAAQ8JK7IKAQors0AKDAkrsAEQsQIBK7EFBemwBRCxCAErtAcFADEEK7ERASsAsQEKERKxBQY5OTAxAREhETMRMxUjNSERIzUhFQFiAXVeXFD9w+YCJwKH/csCh/1x0YcCh1JSAAEAFP+IAowCDAAPAGQAsg8AACuxBgTpsgIBACuwCDOxAQTpsAQyAbAQL7AP1rEGBemyBg8KK7NABgQJK7IPBgors0APAQkrsAYQsQcBK7EKBemwChCxDQErtAwFABsEK7ERASsAsQYPERKxCgs5OTAxEyM1IRUjETMRMxEzFSM1IZqGAWCG+VRRRv5UAcBMTP6MAcD+NLh4AAAAAAEAMv95Al8C2QATAEgAsgsDACuwEjOwBy+xEATpsgcQCiuzQAcDCSsBsBQvsArWsQ0F6bANELEFASuwETKxAAXpswMABQgrtAIFADEEK7EVASsAMDElMxUjNSMRIyImNREzERQWOwERMwIcQ1BQ1FxdXTUr0F1K0YcBBGZaARX+2S0vAYMAAAABACj/iAHhAgwAEgBIALIHAQArsA0zsAMvsQsE6bIDCwors0ADEgkrAbATL7AG1rEJBemwCRCxAQErsAwysQ8F6bMSDwEIK7QRBQAbBCuxFAErADAxISM1IyImPQEzFRQ7AREzETMVIwGbS41BWlREkFQ9Rr9MQ767RgEB/jS4AAEAPAAAAiYC2QAXAGkAsggAACuyEgMAK7AFM7QOFwgSDSuwAzOxDgTpsAkysg4XCiuzQA4MCSuyFw4KK7NAFwEJKwGwGC+wEdaxFAXpsBQQsQwBK7AAMrQLBQAbBCuwAjKwCxCxCAErsAQysQcF6bEZASsAMDEBNTMVMxEzESMRIxUjNSMiJjURMxEUFjMBFEZvXV1vRh9cXV01KwFWiYkBg/0nAQR9fWZaARX+2S0vAAAAAAEAKAAAAaQCDAAUAGkAshAAACuyBAEAK7ANM7QACBAEDSuwCzOxAATpsBEysgAICiuzQAAUCSuyCAAKK7NACAkJKwGwFS+wA9axBgXpsAYQsRQBK7AIMrQTBQAbBCuwCjKwExCxEAErsAwysQ8F6bEWASsAMDE3IiY9ATMVFDM1MxUzETMRIzUjFSPIRFxUTEZCVFRCRr9KRb67RmdnAQH99L9dAAAAAAEAUAAAAjoC2QAPADkAsg0AACuwBTOyDgMAK7QACw0ODSuxAATpAbAQL7AN1rEMBemwADKwDBCxBgErsQUF6bERASsAMDETMzIWFREjETQmKwERIxEzrdRcXV01K9BdXQHVZlr+6wEnLS/+fQLZAAABADwAAAG4AgwADgA5ALIHAAArsAAzsggBACu0CgUHCA0rsQoE6QGwDy+wB9axBgXpsAkysAYQsQEBK7EABemxEAErADAxISM1NCsBESMRMxUzMhYVAbhURJBUVI1BWrtG/v8CDL9MQwAAAAACACj/6QNrAvUACQA2ALAAsgoAACuxMQTpsjEKCiuzQDE0CSuyKQMAK7EGBOmwFyDWEbEeBOmyHhcKK7NAHhsJK7QkEQopDSuwKzOxJATpsAAyAbA3L7AU1rQhBQAxBCuwIRCxEAErsS4F6bAbINYRtBoFADEEK7AQELAlINYRsQkF6bAuELE0ASuwADKxNQXpsTgBK7EbIRESsBc5sRolERKwGTmxNAkRErMGCikxJBc5ALEGJBESsRQhOTkwMQEuBCMiBgcTIi4DPQEuATU0NjMyFhcjNCYjIgYVFBY7ATY3NjMgEyEGFRQWMzI2NzMGAv8FChsmQy1WdRbkTHlHMBFmZ00/N0EEUBsXGB5DMBQXSVKNASwB/egBe2pXXhBfKwHSIS05IhhmW/4XNE9qYjIWAnVTTl07NwobNCo2QnRKVf6bCA+Mok1P7gAAAAACAB7/6QKVAhsABgAzAKcAshIAACuxDATpsgwSCiuzQAwPCSuyKwEAK7EEBOmwBBCwISDWEbQbBAAfBCuyIRsKK7NAIR8JK7QnFRIrDSuwBzO0JwQAKwQrsAAyAbA0L7AY1rQkBQAbBCuwJBCxFQErsCgysQcF6bAAMrAHELEBASuxMgXpsTUBK7EVJBESsRsfOTmwBxGxFB45ObABErIOEis5OTmwMhGwDzkAsSEnERKwGDkwMQEhNCYjIgYHHgMzMjczDgEjIiYnLgE1NDYzMhYXIyYjIgYVFBY7AT4BMzIeBRUBFQEnWTg/UgcBHjAxGmYjVBB2Wmp+BlBOMyokKwQ6BBYOCh8bIgx/YzBMMCMQCQEBLk1TV400SyUQaVZgiXgBVT45QS0nFBkhJSttgBomPTBHIhsAAAAAAgAo/zsDawL1AAkAPAChALISAwArsQYE6bAwINYRsTcE6bI3MAors0A3NAkrsCovsBQzsTwE6bAAMgGwPS+wLda0OQUAMQQrsDkQsSkBK7EXBemwNCDWEbQzBQAxBCuwFxCxIgErtCEFABsEK7AhELEdASuwADKxHgXpsT4BK7E0ORESsDA5sTMpERKxCjI5ObEiFxESsAk5sCERsgYSGjk5OQCxBjwRErEtOTk5MDEBLgQjIgYHIz4GMyATIQYVFBYzMjY3MwYHFSM1LgQ9AS4BNTQ2MzIWFyM0JiIGFRQWMwL/BQobJkMtVnUWXwMJFx0zPlo0ASwB/egBe2pXXhBfKNhIQWc+KQ9mZ00/N0EEUBsuH0MwAdIhLTkiGGZbESA6MTcnGf6bCA+Mok1P4QyvsQc6TmVcLhYCdVNOXTs3Chs0KjZCAAIAHv87ApUCGwAvADYAzgCyDgAAK7ALM7EFBOmyDgUKK7NADg0JK7InAQArsTQE6bA0ELAdINYRtBcEAB8EK7IdFwors0AdGwkrtCMRDScNK7AAM7QjBAArBCuwMDIBsDcvsBTWtCAFABsEK7AgELERASuwJDKxAAXpsDAysAAQsQ0BK7QMBQAbBCuwDBCxMQErsS4F6bE4ASuxESARErEXGzk5sAARsRAaOTmwDRKwNjmwDBGyBSc0OTk5sDESsAc5sC4RsAg5ALERBRESsQcIOTmxHSMRErAUOTAxJR4DMzI3Mw4BBxUjNS4BJy4BNTQ2MzIWFyMmIyIGFRQWOwE+ATMyHgUVJSE0JiMiBgETAR4wMRpmI1QOYkpIW2wFUE4zKiQrBDoDFw4KHxsiDH9jMEwwIxAJAf6AASdYOT9S6jRLJRBpTF4KsLALhm4BVT45QS0nFBkhJSttgBomPTBHIhtETVNXAAEAUAAAAK4C2QADACEAsgIAACuyAwMAKwGwBC+wAtaxAQXpsQEF6bEFASsAMDETESMRrl4C2f0nAtkA//8ADwAAA4QDhBAjAnsBHgCoEgIDigAA//8ACgAAAvMCuhAjAnsA1P/eEgIDqgAAAAEAUP9SApAC2QAaAGEAshQAACuyFQMAK7AYM7AIL7EJBOm0EhoUFQ0rsRIE6QGwGy+wFNaxEwXpsBYysBMQsQ0BK7EEBemyDQQKK7NADQgJK7EcASuxDRMRErAaObAEEbAYOQCxFRoRErAXOTAxATIWHQEUBisBNTMyNj0BNCYrAREjETMRATMBAatcXV1cNDArNTUr+l1dAWt4/mQBd2ZapVpmUi8tyS0v/tsC2f7FATv+ngAAAAABADz/cQHYAgwAGQBwALIGAAArsBEzsgcBACuwCjOwFS+0FgQAQwQrtAMMBgcNK7QDBAA3BCsBsBovsAbWtAUFADwEK7AIMrAFELEZASu0EQUAPAQrshkRCiuzQBkVCSuxGwErsRkFERKwDDmwERGwCjkAsQcMERKwCTkwMSU0JisBFSMRMxU3MwE3MhYdARQGKwE1MjY1AWdDKWxTU95r/vBNTFlZTBopQ1k3MMACDN7e/vwBTUJ6Qk1JMDcAAAABAB7/eQKWAtkAGwBoALILAAArtAwEADYEK7ILDAors0ALGQkrshoAACuyFAMAK7EBBOkBsBwvsBTWsQEF6bABELEbASuxFgXpsxkWGwgrtBgFADEEK7EdASuxARQRErAGOQCxDAsRErEWFzk5sAERsAQ5MDEBIRQWFRQOBCM1Mj4EPQEhETMVIzUjAfH++gEEDhwsRi4ZJRgPCAIBwkdQVQKHElIXRGqEYVYtXiJGUHZnR6n9cdGHAAAAAAEAFP+IAfICDAAbAF0AshMAACuxFATpshMUCiuzQBMFCSuyBwAAK7IAAQArsQkE6QGwHC+wG9a0CQUAPAQrsAsysAkQsQcBK7ECBemzBQIHCCu0BAUAGwQrsR0BKwCxFBMRErEDAjk5MDETIREzFSM1IxEjMBUUDgUjNTI+BDViAVM9RkusAggNGCEyHxIcEAsEAQIM/jS4eAHAMClDWERHLh1QHUFBcVFEAAABAFD/UgKBAtkAEwBOALIEAAArsgUDACuwCTOwDy+xEATptAcCBAUNK7EHBOkBsBQvsATWsQMF6bAGMrADELEAASuwCDKxCwXpsgALCiuzQAAPCSuxFQErADAxIREhESMRMxEhETMRFAYrATUzMjYCI/6LXl0Bdl5eXDQwKzUBTP60Atn+xQE7/TlaZlIvAAABADz/cQHeAgwAEgBUALIHAAArsA4zsggBACuwDDOwEi+0AAQAQwQrtAoFBwgNK7EKBOkBsBMvsAfWsQYF6bAJMrAGELEDASuwCzKxDgXpsgMOCiuzQAMSCSuxFAErADAxBTI2PQEjFSMRMxUzNTMRFAYrAQEfKkH6VFT6VFlMGkYwN8jpAgzX1/30Qk0AAAABAFD/eQLIAtkADwBhALIDAAArsA4zsgQDACuwCDO0BgEDBA0rsQYE6bIBBgors0ABDQkrAbAQL7AD1rECBemwBTKwAhCxDwErsAcysQoF6bMNCg8IK7QMBQAxBCuxEQErALEBAxESsQoLOTkwMQEhESMRMxEhETMRMxUjNSMCJP6KXl0Bd11HUFQBTP60Atn+xQE7/XHRhwAAAAABADz/iAIbAgwADwBhALIPAAArsAozsgABACuwBDO0Ag0PAA0rsQIE6bINAgors0ANCQkrAbAQL7AP1rEOBemwATKwDhCxCwErsAMysQYF6bMJBgsIK7QIBQAbBCuxEQErALENDxESsQcGOTkwMRMzFTM1MxEzFSM1IzUjFSM8VPpUPUZL+lQCDNfX/jS4eOnpAAAAAQA8/3kCJgLZABMARwCyCgMAK7ARM7AGL7EPBOkBsBQvsAnWsQwF6bAMELEEASuwEDKxEwXpswETBAgrtAIFADEEK7ACL7QBBQAxBCuxFQErADAxIRUjNTM1IyImNREzERQWOwERMxEB1lBD1FxdXTUr0F2H0bpmWgEV/tktLwGD/ScAAQAo/4gBpAIMABIARwCyCgEAK7AQM7AGL7EOBOkBsBMvsAnWsQwF6bAMELEEASuwDzKxEgXpswESBAgrtAIFABsEK7ACL7QBBQAbBCuxFAErADAxIRUjNTM1IyImPQEzFRQ7AREzEQFZRj2NQVpURJBUeLh/TEO+u0YBAf30AAABAFD/eQNFAtkAEABVALIEAAArsQAOMzOyBQMAK7AIMwGwES+wBNaxAwXpsAMQsQ8BK7EKBemzDQoPCCu0DAUAMQQrsRIBK7EPAxESsQYIOTkAsQUEERK0AgcKCxAkFzkwMSEjAxEjETMbATMRMxUjNSMRAdliz1iB2NSBR1BPAmP9nQLZ/YUCe/1x0YcCYwABADz/iAJXAgwAEABSALIQAAArsAkzsgABACuwAzMBsBEvsBDWsQ8F6bAPELEKASuxBQXpswgFCggrtAcFABsEK7ESASuxCg8RErEBAzk5ALEAEBESswIFBgskFzkwMRMzGwEzETMVIzUjEQMjAxEjPGiHh2g9RkuCMoJUAgz+ugFG/jS4eAFr/r0BQ/6VAP//AFAAAACuAtkQBgQyAAD//wAPAAACiwOEECMCewCsAKgSAgOEAAD//wAe/+kCCwLeECICe24CEgIDpAAAAAD//wAPAAACiwOEECMAagCuALgSAgOEAAD//wAe/+kCCwK/ECIAanDzEgIDpAAAAAD//wAPAAADugLZEAYAiAAA//8AHv/pA0kCGxAGAKgAAP//AFAAAAJbA4QQIwJ7AKYAqBICA4kAAP//AB7/6QH3At4QIgJ7cgISAgOpAAAAAAACACj/6QKeAuUACQAjAF8AshAAACuxBgTpsh4DACuxGATpshgeCiuzQBgcCSu0ABIQHg0rsQAE6QGwJC+wHNaxGwXpsAAysBsQsRUBK7EKBemxJQErsRUbERK0BhATCR4kFzkAsRgSERKwCjkwMTceBDMyNj8BFA4DIyADITY1NCYjIgYHIzYzMh4DlAUKGyZDLVZ1FmkRL0d3S/7UAQIYAXtqV14QXyvuTHlHMBH8IS05IhhmW2gxYGlOMwFlCA+Mok1P7jRPamIAAP//ACj/6QIBAhsQDwOpAh8CBMAA//8AKP/pAp4DhBAjAGoAtQC4EgIESgAA//8AKP/pAgECvxAiAGpw8xICBEsAAAAA//8ADwAAA4QDhBAjAGoBJgC4EgIDigAA//8ACgAAAvMCvxAjAGoA3P/zEgIDqgAA//8AKP/pAmUDhBAjAGoArgC4EgIDiwAA//8AHv/pAccCvxAiAGpK8xICA6sAAAAA//8AKP/pAk0C2RACAXkAAP//AB7/cQH4AgwQAgI1CgD//wBQAAACigNmECMAcQDHAKkSAgOMAAD//wA8AAAB5wKpECIAcXbsEgIDrAAAAAD//wBQAAACigOEECMAagDJALgSAgOMAAD//wA8AAAB5wK/ECIAanjzEgIDrAAAAAD//wAo/+kC6AOEECMAagDsALgSAgOSAAD//wAe/+kB+AK/ECIAanfzEgIDsgAAAAD//wAo/+kC6ALlEAYD5gAA//8AHv/pAfgCGxAGA+cAAP//ACj/6QLoA4QQIwBqAOIAuBICBFoAAP//AB7/6QH4Ar8QIgBqbfMSAgRbAAAAAP//ACj/6QKdA4QQIwBqALUAuBICA6EAAP//AB7/6QHcAr8QIgBqUfMSAgPBAAAAAP//AA8AAAJgA2YQIwBxAJ4AqRICA5cAAP//AAr/JgHUAqkQIgBxVOwSAgO3AAAAAP//AA8AAAJgA4QQIwBqAKAAuBICA5cAAP//AAr/JgHUAr8QIgBqVvMSAgO3AAAAAP//AA8AAAJgA4QQJxhcAL4AABICA5cAAP//AAr/JgHUAu0QIgKAbgkSAgO3AAAAAP//ADIAAAIcA4QQIwBqAIMAuBICA5sAAP//ADIAAAGuAr8QIgBqWPMSAgO7AAAAAAABAFD/eQI5AtkACQA/ALIGAwArsQkE6bIJBgors0AJAwkrAbAKL7AF1rEABemzAwAFCCu0AgUAMQQrsgIDCiuzQAIICSuxCwErADAxNzMVIzUjESEVIa1DUFAB6f50StGHAtlSAAAAAAEAPP+IAXICDAAJAD8AsgABACuxAwTpsgMACiuzQAMHCSsBsAovsAnWsQQF6bMHBAkIK7QGBQAbBCuyBgcKK7NABgIJK7ELASsAMDETIRUjETMVIzUjPAE24j1GSwIMTP6AuHgAAAD//wBQAAADGgOEECMAagERALgSAgOfAAD//wA8AAACYgK/ECMAagC2//MSAgO/AAAAAQAU/yYCSALZABwAegCyGQMAK7EcBOmwCS+0DwQAQwQrsBYvsAIztBcEADcEK7AAMgGwHS+wFNawGDKxBAXpsAAyshQECiuzQBQWCSuwBBCxEgsrtAcFADwEK7IHEgors0AHAgkrs0AHGwkrsR4BK7EEFBESsQkLOTkAsRYPERKxBAY5OTAxEzMVIxEwMxUUIyInMDUWMzI2PQEjESM1MzUhFSG8ampTjw0PEQMmHl1LSwHp/nQB7Ub+pLhtA0cBHidMAadG7FIAAAAAAQAU/yYBiAIMABwAfwCyAQEAK7EEBOmwDi+0FAQAQwQrsBsvsAcztBwEADcEK7AFMgGwHS+wGdawADKxCQXpsAQysgkZCiuzQAkHCSuyGQkKK7NAGRsJK7AJELEXCyu0DAUAPAQrsgwXCiuzQAwDCSuxHgErsQkZERKxDhQ5OQCxGxQRErEJCzk5MDETNSEVIxUzFSMVMDMVFCMiJzA1FjMyNj0BIxEjNVIBNuJERFOPDQ8RAyYeVD4BSMRMeEa8s20DRwEeJ0wBAkYAAQAP/1ICggLZABMATwCyAwAAK7ALM7IAAAArsgUDACuwCDOwDy+xEATpAbAUL7AA1rQLBQAjBCuyAAsKK7NAAA8JK7EVASuxCwARErAJOQCxBQMRErEBBzk5MDEhCwEjAQMzGwEzAwEUBisBNTMyNgIPx8hxAQLycbu8b/YBAnRbNDArNQEw/tABdgFj/uIBHv6d/opGaFIvAAAAAQAK/3EB0gIMABEATwCyBQAAK7ANM7ICAAArsgcBACuwCjOwES+0AAQAQwQrAbASL7AC1rENBemyAg0KK7NAAhEJK7ETASuxDQIRErALOQCxBwURErEDCTk5MDEFMjUnByMTAzMXNzMHExQGKwEBBWyDhV+5r19+fl6wtVlMKEZGyckBCwEBvr79/vFCTQAAAQAPAAACggLZABEAQACyBwAAK7ADM7IMAwArsA8ztAoJBwwNK7ABM7QKBAA3BCuwADIBsBIvsRMBKwCxCQcRErAFObEMChESsA45MDEBFSMTIwsBIxMjNTMDMxsBMwMCLZbrc8fIceual9hxu7xv3AGcSP6sATD+0AFUSAE9/uIBHv7DAAAAAAEACgAAAdICDAARAEAAsgcAACuwAzOyDAEAK7APM7QKCQcMDSuwATO0CgQANwQrsAAyAbASL7ETASsAsQkHERKwBTmxDAoRErAOOTAxARUjFyMnByM3IzUzJzMXNzMHAZxqoGGDhV+maV2QX35+XpMBOEjwycnwSNS+vtQAAAAAAQAo/+kCZQLlADEAhgCyDQAAK7EABOmyAA0KK7NAAAcJK7IaAwArsSEE6bIhGgors0AhHQkrtCcqDRoNK7EnBOkBsDIvsBPWsS0F6bAXINYRsSQF6bAtELEFASuxBwXpsB4g1hGxHQXpsTMBK7EeJBEStQANGhUoKSQXOQCxKgARErATObAnEbAVObAhErAXOTAxJTI+Aj0BMw4EIyIuAzU0NyY1NDYzMhYXIy4BIyIGFRQWOwEVIyIGFRQeAgE/O1UrE1gBJThOSylBZz4oD4Jpi3h+jAFYAV5XSllfP1hsQ2APJU47HzQ2HwU8XDcjDR4uPTkdfTEtbGNzd2tHTUQ3LltSVC4XKSoaAAEAHv/pAccCGwAjAKEAsgMAACuxIQTpsiEDCiuzQCEBCSuyDQEAK7ESBOmyEg0KK7NAEg8JK7QYGwMNDSuxGATpAbAkL7AK1rEVBemyFQoKK7NAFRoJK7AVELAeINYRsQYF6bAGL7EeBemwFRCxEAErsQ8F6bAAINYRsQEF6bElASuxHgoRErAIObEQFRESswwNAyEkFzkAsRshERKwBjmwGBGwCDmwEhKwCjkwMSUzBiMiJjU0NyY1NDYyFhcjJiMiBhUUFjsBFSMiBhUUFjMyNgFvWAbLY3VWQW62YgFYA2YzPDEwPkorO0A2RTScs1pMViYlS0lXVE1UKyQhNUw2HyUtNwAAAAEAHv9SAk8C2QAfAFUAsgsAACu0DAQANgQrshQDACuxAQTpsBovsRsE6QGwIC+wFNaxAQXpsAEQsR8BK7EWBemyHxYKK7NAHxoJK7EhASuxARQRErAGOQCxAQwRErAEOTAxASEUFhUUDgQjNTI+BD0BIREUBisBNTMyNjUB8f76AQQOHCxGLhklGA8IAgHCXlw0MCs1AocSUhdEaoRhVi1eIkZQdmdHqf0nUlxSLy0AAQAU/3EBtQIMAB0ASACyFQAAK7EWBOmyAAEAK7EMBOmwBi+0BwQAQwQrAbAeL7Ad1rQMBQA8BCuwDBCxCgErsQIF6bIKAgors0AKBgkrsR8BKwAwMRMhERQGKwE1MjY1ESMVFA4FIzUyPgQ1YgFTWUwaNDesAggNGCEyHxIcEAsEAQIM/fRCTUkeKAHAYiU8Tjs9KBlQGTg5Y0g+AAAA//8AKP/FAugC5RAGADQAAP//AB7/JgHzAhsQBgBUAAD//wAPAAADmgLZEAYAOgAA//8ACQAAAscCDBAGAFr/AAABAFAAAAJuAtkAEgAwALIBAAArsBAzsgIDACuwCTMBsBMvsAHWsQAF6bADMrEUASsAsQIBERKxBBI5OTAxMyMRMxE3JzMXNzMHFyMnBwEjAa1dXbFydTJLb31odSinAXp8/rsC2f7Osl0oS31VIKf+gAFNAAEAPAAAAdoCDAASADMAshEAACuwDTOyEgEAK7AGMwGwEy+wEda0EAUAPAQrsAAysRQBKwCxEhERErEBDzk5MDETFTcnMxc3MwcXIycHASMnFSMRj3FYdRguYFpgdSBsARJq4VMCDNRxSBMuWU8abP7u4uICDAAAAAEAUP95AsMC2QAMAFMAsgMAACuxCgwzM7IEAwArsQEE6bIBBAors0ABCQkrAbANL7AD1rECBemwAhCxDAErsQYF6bMJBgwIK7QIBQAxBCuxDgErALEBAxESsQYHOTkwMQEhESMRIREzFSM1MCMCI/6LXgIxQlBQAof9eQLZ/XHRhwAAAAEAPP95AiACDAAMAFMAsgwAACuxBggzM7IAAQArsQoE6bIKAAors0AKBQkrAbANL7AM1rELBemwCxCxCAErsQIF6bMFAggIK7QEBQAxBCuxDgErALEKDBESsQMCOTkwMRMhETMVIzUwIxEjESM8AaFDUEf5VAIM/j7RhwHA/kAAAQAy/3kCXwLZABIAWwCyEAAAK7AJM7IRAwArtAAOEBENK7EABOmyDgAKK7NADggJKwGwEy+wENaxDwXpsAAysA8QsQoBK7EFBemzCAUKCCu0BwUAMQQrsRQBKwCxDhARErEGBTk5MDETMzIWHQEzFSM1IxE0KwERIxEzj+hNWENQUEzkXV0BxlxB39GHATs5/owC2QAAAAABADL/eQHxAgwAFABdALINAAArsQQGMzOyDgEAK7QQCw0ODSuxEATpsgsQCiuzQAsDCSsBsBUvsA3WsQwF6bAPMrAMELEGASuxAAXpswMABggrtAIFADEEK7EWASsAsQsNERKxAQA5OTAxJTMVIzUwIzU0JisBFSMRMxUzMhYVAa5DUEciGJpUVJc7VkrRh8UZGfcCDMlCOQAAAAABAEb/1wLQAswAGQA/ALIMAAArsQAE6QGwGi+wD9axEgXpsBIQsQMBK7EGBemxGwErsQMSERKwDDmwBhGwCTkAsQAMERKxBwk5OTAxJTI2NREzERcHJw4BIyImNREzERQeBQFZck9fVztbIIgxoXpeAQcOGiY6SXB2AZ39rF1EZSQknJ4Bnv5jHSM2IigXDwABAEYAAAJ5AtYAHwBKALIZAAArsBcvtBQEADYEK7ANL7EABOkBsCAvsBnWsRgF6bATMrAYELEHASuxBgXpsBUysSEBK7EHGBESsAA5ALENFBESsAY5MDEBMh4CHQEjNTQuAiMiDgMdASEVIRUjETQ+AwFhUnA9GV8OJ089MUQmFAUB0f4vXw4mPmUC1i1YbElSUTpMQR8bKUxFOIFdlgGcO1pSNB8AAAACACj//wK8AtYAGQAmAFsAsgMAACuwBS+wADO0JQQAKgQrsBgysB0vsREE6QGwJy+wC9axIwXpsCMQsSYBK7ADMrEYBemwATKyGCYKK7NAGBkJK7EoASuxJiMRErAROQCxHSURErALOTAxJSMVIzUjIi4DNTQ+AzMyHgMVETMDNCYjIg4DFRQ7AQK8a1/XP18xHQcIHzprTEJkOSMMbsteSzVKKhcGu7SGh4cvQFU4GjpNWjUkHCo6NBz+4AEVPEoTHzYzJ9kAAAEAPAABAsEC2QAcAFgAsgADACuxEQTpsAkvtAYEADYEK7IJBgors0AJCwkrAbAdL7AW1rEVBemwFRCxCwErsQoF6bAFMrQIBQAMBCuxHgErsQsVERKwADkAsREGERKxFRY5OTAxATIeAh0BMxUjFSMRNC4CJyIGHQEjNTQ+AwFUU3E9GlJSXwwjSzpyT18HIDhtAtkrVm1MsF6QAZ04SEMiAXB2UVIvRl48KwABAEb/9gJ5At0AHwBSALIMAAArsQAE6bISAwArtBQXDBINK7QUBAA2BCsBsCAvsBHWsRgF6bATMrAYELEDASuxBgXpsBUysSEBK7EDGBESsAw5ALEXABESsQQFOTkwMSUyNj0BMxUUDgMHIi4CNREzFSEVIRUUHgUBWXNOXw4lPWREU3I9GV8B0f4vAQcNGyU6TG92UVE5WFI2IQErWGxMAayYXbcbIDYiKhcRAAAAAAEAMgAAAtsC3wAuAJoAshAAACuwCTOyKwMAK7EfBOmxDhAQIMAvsRME6bAGMrITDgors0ATEQkrtCIlECsNK7EiBOkBsC8vsBDWsQ8F6bASMrAPELAiINYRsSYF6bAmL7EiBemyIiYKK7NAIiQJK7APELEaASu0AAUAGwQrswoAGggrtAkFADwEK7EwASuxGg8RErIGHys5OTkAsR8iERKxGgA5OTAxARQOAwczMhcjNCYnIRUjNTMVMzI+AzU0LgIjIgYVMxUhNTQ+AjMyHgECjxwoNCsUe4UDUyEk/llaWn8MO1tPOixHRiJZgbz+5R1Fg11FfVkB1TpoSD0hCoMcFwE0uDcPLEJ2ST1ZLRRzaVEdTHVkNjV9AAAAAQBGAAABoALRAAkAQgCyAgAAK7EJBOmwCC+xBQTpsgUICiuzQAUDCSsBsAovsALWsQkF6bAEMrIJAgors0AJAQkrs0AJBwkrsQsBKwAwMSUVIxEzFTMVIxEBQPpg+vpPTwLR6U3+tAABAEYAAAJ5AtkAHABDALIRAAArsQ4E6bIYAwArsQgE6QGwHS+wEdaxDgXpsA4QsQIBK7EBBemwDzKxHgErsQIOERKwGDkAsQgOERKwATkwMQEVIzU0LgInIg4CFREhFSERND4DMzIeAgJ5Xw4nTz05SSYNAdX9zQ4mPmVEUnA9GQGfjYw5S0IfAR9BTTn+uVcBnztaUjQfLVdsAAACAEb//gMWAtgACQAzAF8Asg8AACuwJDOxBgTpsAAvsDIzsRgE6bAwMrAeL7ErBOkBsDQvsCXWsSQF6bAkELEVASuxAwXpsAMQsQgBK7AZMrEKBemwLzKxNQErsQgDERKwDzkAsQAGERKwFTkwMQEiBhUUFhcyPQEXFA4CIyIuAzU0NjsBNTQmJyMiDgIVESMRND4COwEyFh0BMxUjAc5FLjRZmV8VNXBROFEtGgdXeLQ/VbMeLDEaXy5LTCm/aYQ2NgFwOF5VOAGJm6IlQUMnGic+NyR/aUJBRQIIGTot/f4CCzpVKxNxXEtOAAIAQf/2AnwCzgARABwARACyAwAAK7ESBOmyCgEAK7AOM7EXBOmwEDIBsB0vsAbWsRsF6bAbELEVASuwCzKxAAXpsA0ysR4BK7EVGxESsAM5ADAxJRQGByImPQE0NjczNTMVMxUjAzI2NzUjIgYHFRQCHIFtaoOAbY9cY2DuRUgClkFFAcNbcAJvXn5cbwLAwEv+fjpP+T1Ra4kAAAEARgAAAngC3AAZAFEAsgwAACuyDQMAK7QSBQwNDSuxEgTpsgUSCiuzQAUYCSsBsBovsAzWsQsF6bAOMrALELEZASuxGAXpsRsBK7EZCxESsBI5ALESBRESsA85MDEBNC4CIyIGBwYVESMRMxU+ATMyHgIdASMCGg4lSThKZwoHXmIKeS9Ucz4ZXgEBOE1BHzQ1JTr+4gLc1hciLVpsS0cAAAAAAQBGAAABXgLMAAUANQCyAAAAK7QDBAA2BCuyAwAKK7NAAwEJKwGwBi+wANaxAwXpsgMACiuzQAMFCSuxBwErADAxMxEzETMVRl+5Asz9kl4AAAAAAQBG//QDEwLTABwAWQCyEwAAK7IKAAArsQAE6bIWAQArsAYzsREE6bIWEQors0AWFAkrAbAdL7AT1rESBemwFTKwEhCxDwErsRgF6bAYELEFASuxCAXpsR4BK7EFGBESsAo5ADAxJTI+Aj0BMxUQIyIuAj0BIxEjETMVMxUUHgICJCMtKxVf8FRwORZrX1/LDCVJSQ8sYEvg4f7GLFlqTJH+QALTw+E5S0EgAAIAI//8AwAC+gAiAC4AcgCyFQAAK7EsBOmyAgIAK7EfBOmwCzKyAgIAK7QmBAAQBCuwBzIBsC8vsBjWtCkFADwEK7ApELEjASuxEgXpsTABK7EpGBESsAA5sCMRswIVHgwkFzmwEhKxAwc5OQCxJiwRErESGDk5sQIfERKwBjkwMRMWMyEyHwEHLgIjJx4EFRQGIyImNTQ+AzcnIj0BATQmIyIGFRQWFzI2dgRcAZ9eJAlBBBYTEH4PJzwvI8mIi70mNTomBlF8AlCMZ2qUjmRkmQL6Ny0QPxQVAwEGFjVDaj6Js8GNOGZDNBcBAVEI/mtwmqNrYJACjwAAAAEARgABAnkC3QAcAFMAsgYDACuwAC+xDgTpsgAOCiuzQAAZCSuyDgAKK7NADhYJKwGwHS+wBdaxCAXpsAgQsRkBK7AVMrEYBemxHgErsRkIERKwADkAsQ4AERKwGjkwMSUiLgI1ETMRFB4DFzI+BD0BMwMjNQ4BAWRUcj4aXgQUJEcyLkMpGQsDXwFhClyfLFhtTAEB/wApNEMnHgEOISI+LilM/djXFSQAAAABABT/tgI0AtUAEwAlALAFL7EABOkBsBQvsAvWtAoFABEEK7EVASsAsQAFERKwAjkwMQEyFxUmJyIHAQUVIy4DJyUBNgH1LBMYHSUn/vEBgCAGGy8RFf6GAXQtAtUPZx4CLv64sKMfMCIKCqoBuDgAAgAy/9YCTwLYAC8AOAByALIbAAArsTUE6bIUAAArsDAvsSEE6bAAL7EJBOkBsDkvsAXWsQQF6bAeINYRsTIF6bAEELEpASuxDQXpsToBK7EpBBEStwkQFBsmMDU3JBc5ALE1GxESsRMXOTmwMBGyEB4mOTk5sQAhERKxBAU5OTAxASIGHQEnNTQ2MzIWFxUUBgceAhcHJicOAgciJjU0NjcyHgIXPgE9ATQuAwMiFRQWMzI3JgFLRFtfj290jgJlVg4bHwlJLxwoORYTT0ZBOhAkNTUTP1UdKTIjmjUgHh8yKgKNV0c9AkJYiodvP2OwPAweKAoiJycVFgMBSyo+QwIGEisgKKJZLCtEJRkH/g8wExkjOQAAAAEAQQAAAnwC2AATAEsAsgcAACuxBATpsAsvsQAE6QGwFC+wENaxDwXpsA8QsQcBK7EEBemyBAcKK7NABAYJK7EVASuxBw8RErAAOQCxCwQRErEPEDk5MDEBMhYVETMVIxE0JiciBh0BIzU0NgEuaoNhwD1RQ0tfggLYcVz+QEsCBUBGAjxMzNJacwAAAgAoAAACagLUABkAIgAYALIBAAArtCIEACoEKwGwIy+xJAErADAxKQE0PgMzJic3HgMXNjcXBgcyHgMnAiciDgMHAmr9vis7PykDGS88Ch0PFww/hkJ3QwQsQDwrWEGCAiAxMy8LYLV5XiwSEkcDCQUMCDk9QzUvMmaAtwIBCoYoTF9/PgAAAAEAPP/2AtkC2QAZAEkAsg8AACuxAATpsgYDACuwFTO0CQQANgQrAbAaL7AU1rEXBemwFxCxBQErsQoF6bIKBQors0AKCAkrsRsBK7EFFxESsA85ADAxJTI+AjURMxcHERQOAiMiLgI1ETMRFBYBXDhKJQ7HAWoZPnFTUnA9GV9OSyBCTDcBqV0B/rVNbVYqLVhsSQGo/lh2bwAAAAEALf/0AiYC2AA0AI0AsgYAACuxEATpshAGCiuzQBAJCSuwHS+xHgTpsCQvsS0E6bIkLQors0AkKAkrAbA1L7AJ1rEKBemwKCDWEbEnBemwChCxFwErsQMF6bAhINYRsTMF6bE2ASuxKAkRErEdHjk5sSEnERKyBhAtOTk5sBcRsAA5ALEdEBESsAM5sB4RsAA5sCQSsDM5MDEBHgEVFAYjIiY1MxQeAzMyPgQ1NC4CKwE1MzI1NCYjIgYVIzQ+AjMyHgMVFAG7KUKSbnmAXR4oMh4JBxQpIyMVITUtFujnhVg0NUdgFS5bPzVUMiEMAYIFY09kc3tTITMaEQQCCBQeNSEtPRsKTXM6MzUsHDc3IhgmMzEZeQABAAr/9wLXAtkAGwBSALIBAAArsRIE6bIIAwArtAcEADYEKwGwHC+wBdaxCgXpsgUKCiuzQAUHCSuwChCxFQErsRgF6bEdASuxFQoRErEAATk5ALEHEhESsRYXOTkwMQQiLgInESM1MxEUHgUzMjY9ATMVFA4BAhKmbz0aApr5AQcOGiY5JXNOXxg8CSdVbVEBSl7+WBshNiIpGBBvdpWVSWpZAAEAKP/0AiwC4wAgAJMAshoAACuxDwTpsgUDACsBsCEvsCDWsQwF6bAMELEUASuxFwXpsSIBK7A2Grryl8FsABUrCrAFLg6wBsCxBAT5sAfAswMEBxMrswkEBxMrsgMEByCKIIojBg4REjmwCTkAtAMEBgcJLi4uLi4BtQMEBQYHCS4uLi4uLrBAGgGxFAwRErAaOQCxBQ8RErEVFjk5MDETNDY3JzUFFSYnIh0BFBYXMj4CPQEzFRQGIyIuAzUoblKMAaZgJPRYSw8qPSlgjnE7XzglDgFNc5QdHlRhUxUH/ltSWwYKHEYyQEZZiiU3QTMTAAABAEYAAQJ5AtkAGgA9ALIWAwArsQgE6bIIFgors0AIDgkrsAEyAbAbL7AP1rEOBemwDhCxAgErsQEF6bEcASuxAg4RErAWOQAwMQERIxE0LgInIg4CBxEjETQ+AzMyHgICeV8OJ089OUklDQFeDiY+ZURScD0ZAZ/+YgGdOUtCHwEfQUw6/mMBnjtaUjQfLVdsAAAAAQBC//ICRwLYACMAkgCyBwAAK7ATL7EdBOkBsCQvsBjWsRcF6bAXELENASuxAAXpsSUBK7A2GrrvncIiABUrCrAHLg6wCMCxBhH5sAnAsAkQswUJBhMrswoJBhMrsgoJBiCKIIojBg4REjmwBTkAtAUGCAkKLi4uLi4BtQUGBwgJCi4uLi4uLrBAGgGxDRcRErAdOQCxEwcRErAYOTAxARQOAgcfASU1Fz4BPQE0LgInIgYHFQc1NDc2MzIeAxcCRy1KVC2XAv5ug4GMHjYxIUdXAV9AS3M+YzUkCwEBgjxlQyoIKFJpVSULh3VVL0IiDwRVSUABSFNESyc2RC8SAAEAQQABAnQC2QAaAFQAshYDACuxCwTpsAgysgsWCiuzQAsBCSuzQAsKCSuzQAsPCSsBsBsvsA/WsQ4F6bAOELEKASuxCQXpsAkQsQIBK7EBBemxHAErsQkKERKwFjkAMDEBESMRNC4CJxEjESIHFSM1ND4DMzIeAgJ0XxMsKydhgQNeDiY+ZURScD0ZAZ/+YgGdQlYwFQr+WgGl5iorO1pSNB8tV2wAAAIALQAAAsoC3wAOADkAnQCyHwAAK7AYM7I0AwArsQcE6bEdHxAgwC+xIgTpsBUysiIdCiuzQCIgCSu0DSsfNA0rsQ0E6QGwOi+wH9awLTKxHgXpsCEytA0FADEEK7AeELECASu0EAUAGwQrsxkQAggrtBgFADwEK7E7ASuxDR8RErAsObECHhEStQAHFSYrNCQXOQCxKyIRErAAObANEbEQLTk5sAcSsA85MDEBNjc0LgIjIg4DFSA2FA4DBzMyFyM0JichFSM1MxUzMjY1NC4CIyYnNTQ+AzMyHgMCCSkDKkhMKzBMLB0KAV+iHCg0KxR7hQNTIST+WVpaf0RrPmdJKW4HDyk+aUIYMks/OgEZVUg/XC4VIjNBNRdddGhIPSEKgxwXATS4NzkzJzQVBgMCWSNHUDwoBhElNwABAEYAAQLEAtkAHgBSALIaAwArsQwE6bAEL7EBBOmyBAEKK7NABBIJK7AFMgGwHy+wE9axEgXpsBIQsQYBK7EFBemwADKyBQYKK7NABQMJK7EgASuxBhIRErAaOQAwMQEVMxUjFSMRNC4CJyIOAgcRIxE0PgMzMh4CAnlLTlwOJ089OUklDQFeDiY+ZURScD0ZAZ+lUagBnTlLQh8BH0FMOv5jAZ47WlI0Hy1XbAAAAAEARv/0AnkCzAAWAD0AsgsAACuxAATpsgALCiuzQAAECSuwDzIBsBcvsA7WsREF6bARELEDASuxBgXpsRgBK7EDERESsAs5ADAxJTI2NREzERQOAiMiJjURMxEUHgMBWXJPXxc6c1Shel4EFCRHSXB2AZ3+YkZoXDCcngGe/mMoM0UpHQAAAAABAEEAAQLOAtkAIABYALIYAwArsBwvtBoEADYEK7AAL7EQBOkBsCEvsAXWsQgF6bAIELEXASuwHTKxGQXpshkXCiuzQBkcCSuxIgErsRcIERKwADkAsRAAERKwHjmwGBGwBjkwMSUiLgI9ATMVFB4FMzI+BD0BMxEzFSM1DgEBX1RyPhpeAQcNGiY6Ji5DKRkLA19avApcnyxYbUxlZCAhOR8pFQ8OISI+Lin8/YZe1xUkAAABAC3/9AJnAtgALgEUALIjAAArsSwE6bIsIwors0AsKQkrsBUvsQsE6bIVCwors0AVEQkrAbAvL7AI1rEYBemwKSDWEbEqBemwGBCxAAErsSAF6bASINYRsREF6bEwASuwNhq67WrCwgAVKwoOsAUQsALAsRoJ+bAdwLrx08GXABUrCrEFAgiwBRAOsAPAsRodCLEaEvkOsBzAsQUDCLAFELMDBQITK7rvjsImABUrC7MEBQITK7EFAgizBAUDEyu67sfCXAAVKwuwGhCzGxodEyuxGh0IsxsaHBMrsxwaHRMrALcCAwQFGhscHS4uLi4uLi4uAbcCAwQFGhscHS4uLi4uLi4usEAaAbESGBESsgsjLDk5OQCxFSwRErAgOTAxJTQuBSc0NjMyHgMVIy4BJyIGFRQeBRUUBiMiLgM1MxYzMjYCCzBNXmBPNgORa0hsNB8GWwZWUkpaMk9hYE8ymHFGbkIrEFkOxkhpwigzGhMaJ085XGkoNUQmD0M+Ajc1JDAaFhwpTzdceiAyRD4gnz8AAAEARgABAnkC2QAaADoAshYDACuxCATpsggWCiuzQAgOCSsBsBsvsA/WsQ4F6bAOELECASuxAQXpsRwBK7ECDhESsBY5ADAxARUjNTQuAiciDgIHESMRND4DMzIeAgJ5Xw4nTz05SSUNAV4OJj5lRFJwPRkBn3l4OUtCHwEfQUw6/mMBnjtaUjQfLVdsAAAAAAIAPP/0AjkC2AAoADMAnQCyDwAAK7EWBOmyFg8KK7NAFhIJK7AiL7QsBABDBCuwMi+xBQTpAbA0L7AA1rEqBemwKhCwEyDWEbESBemwEi+xEwXpsCoQsRwBK7EMBemwLiDWEbEHBemxNQErsQASERKwJTmxKhMRErAnObAuEbQPFiIkBSQXObAcErAJOQCxIhYRErIMJCU5OTmwLBGxCSc5ObAyErEHADk5MDETND4CMzIVFAceARUUBiMiJjUzFBYzMj4DNTQuAyMiByc2NyY2FBYyNjU0LgEjIk8TLmJG6lgpRo1zcYxdV0kUKS0iFhkjLyQSaCNqFUpVW1J4UDE7IToCIB85PCS4ZSUKa05ifXdgP00HFR82IyU5HhMFNQFBIB6eYEA3OSgzEQAAAAABAEYAAAFZAtMABwA4ALIHAAArsAUvsQIE6bICBQors0ACAAkrAbAIL7AH1rEGBemwATKyBgcKK7NABgQJK7EJASsAMDETMxUzFSMRI0ZftLRfAtP4UP51AAAAAAMALQABAucC1QAeACcALQBtALAAL7AcM7EnBOmwKDKyACcKK7NAAB4JK7AfL7AtM7EMBOmwDzKyDB8KK7NADA0JKwGwLi+wBtaxJQXpsCUQsR4BK7EMHzIysR0F6bEOKDIysB0QsSoBK7EVBemxLwErALEfJxESsRUGOTkwMSUuBDU0PgM3NTMVMh4DFRQOBAcVIxEOBAcUFzM2NzQmJwFcHDxeRTQyRF09H14SO1xMOCE5QEg0F14VLD0vIgHQXssGb2IwAw8sP3RJR3A+LA8ENzcLKD92TDxjQTAbDQIvAk4CDCAwVDXCKCXFZXUNAAIAHgAAAlAC2AAUACIAaQCyDQAAK7APL7AKM7EQBOmwCDKwBi+xHATpsBUvsQAE6QGwIy+wEdawDTKxCAXpsQsYMjKyEQgKK7NAEQ8JK7AIELEeASuxAwXpsSQBK7EeCBESsQUAOTmwAxGwAjkAsRwGERKwBzkwMQEyFhcUBiInFSEVIRUjNSM1MxE0NhciBh0BFBYzMjU0LgIBY2l8BHPYLgF9/oJdV1eDaz1SXT2AGy0sAthuYXSCPIhOeXlOAURccUtKPS40RJ8oOx0NAAACAC3/9ALaAtkACwAfADgAsgMAACuxFQTpsgkDACuxDATpAbAgL7AG1rESBemwEhCxGgErsQAF6bEhASuxGhIRErADOQAwMQEUBiMiJic0NjcyFiUiDgMVFBYzMj4CNTQuAwLawJaZvAK8m5a+/q0gPUUyIoZuKU9NMCEzQz0BZaTNz5quzALMeg0nP3BJfpgbPHdSQmk/KQ8AAAADACj/+AKiAtUADQAUADIAigCyGAAAK7EHBOmwIjKwBi+wIzOxLgTpsBAysBMvtCwEADcEKwGwMy+wKda0DgUAGwQrsA4QsCAg1hGxHwXpsB8vsSAF6bAOELEiASuwETKxBwXpsC0ysAcQsQ0BK7EVBemxNAErsQ0HERKwGDmwFRGwMTkAsQYHERKxHyA5ObETLhESsQ4pOTkwMQE0LgIrAREzMj4CNQEUOwE1IyIBFAYHIyIuAzUzFDMRJyIuAjU0NjsBFTMyFhcCQxwvLBcuLhgtLRz+WW0iKWYCBoFshUFjNyMKXactGTQ4I2loXy5qfgUBETBEIAz+kg4fPysBaEeS/kdfewIZJDQtGW0BcAENHDspWD3ZcGIA//8ATwJDAKcC8hAGAmIAAAABADUB6QCbAtMACQAyALAAL7QBBAAeBCsBsAovsADWsQMF6bADELQJBQARBCuwCS+xCwErsQkAERKwBjkAMDETNTMVFAYHJzY1PV4eMxU1Am1mUDlHGiIUTgAAAAEAHgJMAK0CzgADACAAsAAvtAEEABAEKwGwBC+wANa0AgUADgQrsQUBKwAwMRM3MwceWDdpAkyCggAAAAEAGwJBATIC2gAQADcAsggDACuwDi+0AwQAHwQrAbARL7AQ1rQJBQAIBCuxEgErsQkQERKwCDkAsQMOERKxAAk5OTAxEz4BMzIWMzI3FQYjIiYjIgcbDDYbED0RLDAuLhsvFDglAngTIgMwNzADNf//ABYCUADnAuQQBgBDAAAAAQANAkwBMQMZABkAewCyFQMAK7QFBAAfBCuyFQUKK7NAFRkJK7IHAwArsAsvtBEEAB8EK7IRCwors0ARDQkrAbAaL7AZ1rQYBQARBCuwGBCxDQErtA4FABEEK7AOELETASu0CAUAEQQrsRsBK7EODRESsQUVOTmwExGwCzkAsRURERKwCDkwMRM0PgIzMhYVFAYjIjUzFBYzMjU0IyIdASMNECNFLzpDNCpVNxIOJUhuNwJ/GTIxHj8vLDNhFBYpN2UqAAEAFgI9ATMCxAAGAC0AsgMCACuwAC+0BAQAHwQrAbAHL7AB1rQFBQAHBCuxCAErALEEABESsAE5MDETJz8BBzMVIQtUSlHQAj0yVAFQNwAAAQBB//YDAAIMACEAdQCyDwAAK7ALM7EXBOmwADKyEgEAK7EEHTMzAbAiL7AR1rEUBemwFBCxHAErsR8F6bAfELEDASuxBgXpsAYQtAcFACYEK7AHL7EjASuxHBQRErAPObAfEbANObADErALOQCxFw8RErEGBzk5sBIRsQgNOTkwMSUyNjURMxEjNQ4BIyInBiMiNREzERQWMzI+AjURMxEUFgIoRTtYTxVUNHQePWOhWCQ4FSgpGVgqQl9aARH99UkkMFtbrgFo/rU/QAweQS4BMf6rOTwAAQBG/zgB6wIXABsAYgCyDwAAK7QMBAArBCuyDwwKK7NADxEJK7ISAQArshYBACuxCQTpAbAcL7AR1rEQBemwCzK0FAUAJgQrsBAQsQEBK7EABemwDTKxHQErsQEQERKwFjkAsQkMERKxABQ5OTAxJSM1NC4EIyIdASEVIRUjETMVNjMyFhcWFQHrWAEGDRcmGooBS/61WE88aCxPFiHDYhocLxkcDbHZQsgC1E1YIxosaAAAAgAj/zgCMQIXABMAIQCQALIRAAArtBQEAEMEK7AJMrIRFAors0ARDgkrsgwAACu0CQQAKwQrsgcBACuyAwEAK7QaBAArBCsBsCIvsADWsR8F6bAfELEXASuwBjK0CQUAMQQrsAwysgkXCiuzQAkLCSuwCRCxDgXpsA4vsSMBK7EOHxESswMRFBokFzkAsRQMERKwDzmwGhGxAAY5OTAxEzQ2MzIWFzUzETMVIxUjEQYHIiYXMjY1NCYjIg4CFRQWI3hjN0MdUExMWDNVZX3oN1NPPxYsLRtWAQx6kScoRP42QsgBAz8DnFNZal1wEilSOG1eAAEAQf84Ai8CFgAeAHcAshIAACuwGzO0DwQAHwQrshIPCiuzQBIUCSuyHQEAK7ILAQArsRcE6QGwHy+wHNaxGwXpsAAysBsQsRQBK7ETBemwDjKyExQKK7NAExEJK7EgASuxFBsRErEECzk5sBMRsA05ALEXDxESsAA5sB0RsQQHOTkwMRMwNz4HMzIWFxEzFSMVIxE0JyIGFREjETOUBgYGDwwVFRshEkJMBGRkWE5HRVhTAbwJCQYTCRAICgREPv6qPsgCNlwBX0v+3wIMAAABAEH/9QHqAtEAGgBaALIGAAArsgkAACuxAATpsBcvtBQEACsEKwGwGy+wEdaxGAXpsBMysBgQsQIBK7EEBemwBBC0BgUAJgQrsAYvsRwBK7ECGBESsAk5ALEXABESsgMEBzk5OTAxJTI9ATMRIzUGIyIuBTURNxUhFSEVFBYBBYpXTzprJDklGg0HAVgBUf6vL0GrYf6zSlUQGCchMRwWAgcC7kLVREcAAAAAAgAj/zgCOwIZABEAHQBwALIKAQArsgYBACu0GwQAKwQrsA8vtAwEAB8EK7AAL7QVBAA3BCsBsB4vsAPWsRIF6bASELEYASuxCQ8yMrQLBQA8BCuyCxgKK7NACw4JK7EfASuxGBIRErEABjk5ALEbFRESsQMQOTmwChGwCTkwMTciJjU0NjMyFhc1MxEzFSMRBgMUFhcyNjc0JiMiBuxXcnFmN0cOUmO4MdZIQzpDAkFDRUEFlm11nCsYNv1nOwEZTAEHVGkEdEtWdHIAAQBG/4cBTQLRAAsAWACyAwAAK7ELBOmyAwsKK7NAAwEJK7AKL7QHBAArBCuyBwoKK7NABwUJKwGwDC+wBNaxCwXpsAYysAsQsQIBK7QBBQAmBCuyAQIKK7NAAQkJK7ENASsAMDElFSc1IxEzFTMVIxEBJkyUVrGxSsMCdwLR/kL+uQAAAQBB/zgB5gIRABYAXQCyEAAAK7ILAQArsQAE6bAGL7QDBAAfBCsBsBcvsAbWsQMF6bQJBQAmBCuwAxCxEAErsQ8F6bEYASuxEAMRErALObAPEbEFBDk5ALEAEBESsAk5sAsRsQcIOTkwMQEiFREhFSERMxU2MzIWFREjETQuAwEjigFJ/l9PPGljTlgDDBcoAcax/mNAAs5NWG9i/r8BICErLxoSAAAAAgBG/zgCKgIZACQALQCBALIWAQArshsBACu0DgQAKwQrsAMvtCUEACsEK7ApL7AjM7QJBAAfBCuwITIBsC4vsBXWsRQF6bQYBQAmBCuwFBCxBgErtCwFACYEK7AsELEKASuwJzKxIQXpsAAysS8BK7EKLBESswMOGyUkFzkAsSklERKwBjmxDgkRErAYOTAxJRQGIyImNTQ2OwE1NCYjIg4CFREjETMVPgEzMh4CHQEzFSMHMj0BIyIGBxQCAmFFQkhZQj0+Oig/IA9WThhUJUJeKxEpKKZQSCAkAqlHXkpDPlhBNzkmNy4O/fkC1EEsIiQ4MRhQPKNlQDQoSQAAAAIAI//9AjkC3gATAB4AYgCyDgAAK7QUBAA3BCuyBQMAK7IDAQArsAcztBsEACsEK7AJMgGwHy+wANaxHQXpsB0QsRkBK7AEMrELBemwBjKyCxkKK7NACwkJK7EgASuxGR0RErAOOQCxGxQRErAAOTAxEzQ2OwE1MxUzFSMVFAYjIi4DFzI+Aj0BIyIHFCNtYoxZYmJ9XzFPLh8L4Cc0Ggl6hQUBDWiX0tJE62Z6JTlLRagiRlE7kb3GAAAAAQBG/zgB7ALMABQAVQCyEQAAK7IMAQArsQAE6bIADAors0AABwkrsgwACiuzQAwICSsBsBUvsAfWsQYF6bAJMrAGELERASuxEAXpsRYBK7ERBhESsAw5ALEMABESsAo5MDEBIg4CFREjETMRNjMyFhURIxE0JgEnGCotGlhYPl1kT1g0AccOIkgz/hwDlP7/R2hh/rcBST8+AAAAAQBG/zgBAAIMAAUALQCyAwEAK7ACL7QFBAAfBCsBsAYvsALWsQUF6bIFAgors0AFAQkrsQcBKwAwMQUVIxEzEQEAuliPOQLU/WUAAAEARv84AtoCyQAaAHkAsgYAACuyCQAAK7EABOmyCQAKK7NACRMJK7IWAQArsAMzsREE6bIWEQors0AWFAkrAbAbL7AT1rESBemwFTKwEhCxDwErsRgF6bAYELECASuxBQXpsAUQtAYFACYEK7AGL7EcASuxAhgRErAJOQCxEQARErAHOTAxJTI1ETMRIzUGIyIuAzUnIxEjETMVMxEUFgH4ilhPOWwxRCQTBQGWWFjvKz+rASL980pWGyVENy3g/X0Dkb3+vkJGAAAAAAIAI//4AgMC7AAXACQAgQCyBQAAK7QjBAA3BCuwAC+0FQQAKwQrsAsysBUQtB0EAB8EKwGwJS+wCNaxIAXpsCAQsQ4BK7QTBQAmBCuwExCxGAErsQMF6bIDGAors0ADFwkrsSYBK7ETDhESsgUMIzk5ObAYEbMQERUdJBc5sAMSsAA5ALEAIxESsQggOTkwMQEeARcQIyImNTQ2MzcmJzQ3FwYHFBczFQc0LgIjIgYVFBYzMgGdEyIG02V9flAWPQNVMzsBXpJ/CBQrHlpKQkl5AcQOXEz+6pp2dY4BKkM9NjQWKDJARLsTOEkxY2VbbQAAAAABAEb/OAHtAtEAEwBKALIMAAArsQAE6bIMAAors0AMCQkrsgYBACsBsBQvsA/WsRIF6bASELEJASuwBTKxCAXpsRUBK7EJEhESsAw5ALEADBESsAo5MDElMj4CNREzESMRBgciJicRMxEUAQwXKi0bWFg9X2ZLAlhHDiJIMwEa/SwBCkUCaWECDP30fgAAAAABAEYAAAHsAswAFABNALIHAAArsBAzsgwBACuxAATpsgwACiuzQAwICSsBsBUvsAfWsQYF6bAJMrAGELERASuxEAXpsRYBK7ERBhESsAw5ALEMABESsAo5MDEBIg4CFREjETMRNjMyFhURIxE0JgEnGCotGlhYPl1kT1g0AccOIkgz/uQCzP7/R2hh/rcBST8+AAAAAgAj//IB0wLgACYANAB2ALIPAAArshMAACu0KgQANwQrsiMDACsBsDUvsBbWsScF6bAnELEgASuxJgXpsiYgCiuzQCYCCSuwJhCxDwErsC8ytA4FACYEK7E2ASuxJiARErEeIjk5sA8RtwkKExscIyoyJBc5ALEjKhESswoQFjIkFzkwMRIyFRQOBQceARURIzUOASMiJjU0PgM3NC4BJzQ3Mw4BFQMUFjMyPgI1NCYjIgb+jgYNDRQNFgNLVk0KRDlkeDFISj4HQEQFKUgDEoJFRio6GAlIOT1SApktBxARDhILEQMPg1/+7D8aM5x2NGJIOzANBQQPEy0uCyAF/lBVcy5KOBpVbn0AAAEAQf84Ai4CEgAWAFcAshAAACuyAAEAK7ARM7EMBOmwCS+0BgQAHwQrAbAXL7AQ1rEPBemwEjKwDxCxCQErsQYF6bIGCQors0AGCAkrsRgBK7EJDxESsAA5ALEMEBESsBM5MDEBMh4CFREzFSMRNCciBxEjETMVPgIBOCk9Hg5kuVF3FFhSHRlCAhIbKikU/ec/AjJcAYr+wwIMVyQbHgACACwAAAH7AtsADwAYAGAAsg8AACu0GAQANwQrsgcDACsBsBkvsADWtBgFACUEK7AYELEQASuxDAXpsA4ysRoBK7EYABESsAM5sBARswQFAgokFzmwDBKwBzkAsRgPERKwDDmwBxGyAgoTOTk5MDE3NDcnNxc2NxcGBxYRMBUhJTQmJw4DFSyhQDE+ZmgxJ5Wz/joBZWIgASgpIx/W2DFAMntUMCeexv7/H0Zd1ywDSVSDPQABAEH/9gHNAugALQCDALIXAAArsBwzsh8AACuxKATpsiMBACuwDS+0CgQAKwQrAbAuL7Ai1rElBemwJRCxBQErtA8FADwEK7APELEtASuwFzKxFgXpsS8BK7EFJRESsR8oOTmwDxGwAzmwLRKwLDmwFhGyDBILOTk5ALEoFxESsBg5sQ0jERKyAwUSOTk5MDEBNC4CNTQ+AjsBFSMiFRQeAxURIzUOBSMiJicRMxEUFjMyPgI3AXUrMysYLSwfTVQ2HSoqHVQHKQwhFSESQVEBWCQqLDobCwIBtB02JkAmGyQQBkQXDyUmKzke/k84BRsHEQUFRzYBmf6NLSsaMiofAAAAAAH/7P84ALMCDAAQAC0AsgcBACuwDC+xAATpAbARL7AG1rEJBemxEgErALEADBESsA45sAcRsA85MDEXMj4DNREzERQGIyInNxYmDxULBQFYOUkqGxEbewwQHxYVAiH94l5YCUsHAAAAAQBG//YBzgLpABoAZgCyBgAAK7IJAAArtAAEAEMEK7IDAQArsBQvtBIEAB8EKwGwGy+wDNaxGAXpshgMCiuzQBgTCSuwGBCxAgErsQUF6bAFELQGBQAxBCuwBi+xHAErsQIYERKwCTkAsQMAERKwBzkwMSUyNxEzESM1BiMiJjURND4COwEVIgYVERQWAP9fGFhQV09BURElTTNBX0AxP4cBRv30U11GNAG8FTlCLT08RP5oMCUAAAEAI/89AXoCEQAgAFoAsggBACuxAwTpsBgvtBUEACsEKwGwIS+wGtaxEwXpsBMQsQABK7ELBemwFjKxIgErsRMaERKxBQY5ObAAEbIDEB05OTkAsQMVERKyBQsaOTk5sAgRsAY5MDEBNCYjIgcnNjcyFhUUBw4EFRY7ARUhIjU0PgE3PgEBIzMoMy4rPFVFaCwsUyghCgRcm/7/UzKEIRwNAVUqRDg6SQNnRTpBQ3Y3MRsQH0JWIFe1MisgAAAAAAEAQf//AeYCFwAXAEsAsgUAACuwEDOyBgEAK7IKAQArsQAE6QGwGC+wBdaxBAXptAgFACYEK7AEELERASuxEAXpsRkBK7ERBBESsAo5ALEABRESsAg5MDEBIgYHESMRMxU2MzIeAhURIxE0LgMBI0k/AlhPPGk4SyIMWAIMFSoBzFxV/uQCDU1YJUNAKf65ASYgJTIcFAAAAQAj/zkBZQITACkAZgCyBwEAK7AfL7QcBAAfBCsBsCovsCXWsRoF6bMFGiUIK7EOBemwGhCxAAErsRMF6bErASuxBSURErAnObEOGhESsQMXOTmwABGyBxYoOTk5sBMSswgKERUkFzkAsQccERKwJTkwMTc0LgInNDcXDgQVFB4CFRQPAQYHBhUUOwEVIyIuAzU0PwE22yUuLQZ1VgMvEh8NKTEpF0VKCwZgiYknMDQcEieLBMkRJBwoFCaXEwQ3FioaCQcjJTETFiBeZRgQDCo/AwsVJhsgOMMGAAEAQf84AwACDAAjAHgAsg8AACuwCzOxGQTpsAAysg8ZCiuzQA8HCSuyEgEAK7EEHzMzAbAkL7AR1rEUBemwFBCxHgErsSEF6bAhELEDASuxBQXpsAUQtAcFACYEK7AHL7ElASuxHhQRErAPObAhEbANObADErALOQCxEhkRErEIDTk5MDElMjY1ETMRIxEOASMiJwYjIjURMxEUHgIzMj4CNREzERQWAihFO1hPFVQ0dB49Y6FYBREoHhUoKRlYKkJfWgER/SwBEiQwW1uuAWj+tRslKRYMHkEuATH+qzk8AAAAAAIAJv83Ac8CFAAjADUAhgCyAAEAK7EkBOmwEC+0DQQAHwQrAbA2L7Ad1rEnBemwEiDWEbELBemwJxCxFwErtC0FABEEK7ItFwors0AtDgkrsC0QsTMBK7EFBemxNwErsScSERKwGjmwCxGxFSY5ObAXErAqObAtEbIJCCQ5OTmwMxKwBzkAsSQNERKzBxIdLSQXOTAxEx4DFxQPAQ4BFRQ7ARUjIjU0PgI1NC4DNTQ+BBciBgcUHgMXPgQ1NCbvQV0uEwGfNyofa4LGhSUrJSEwLyEXKSk0HQo5LwQaJSUaAQUPKB8ZOQIUAi5HQiOajCwiIAwiP0gXMCMyGR0tJCtMNC5HKRsLA0pCQCE3KCpAKQURNzlSJkVSAAAAAQBBAAAB6AIXABsAZgCyGwAAK7AJM7QYBAArBCuwADKyCwEAK7IPAQArsQYE6QGwHC+wCtaxCQXptA0FACYEK7AJELEEASuxFAXpsR0BK7EECRESswAPGBskFzmwFBGxGRo5OQCxBhgRErIDDRQ5OTkwMTcyPgE0JiMiFREjETMVNjMyHgIVFAYPATMVI/0JR0Q6NIpYTzxoM0slES0RcHSxP1uLZkGx/uUCDE1YJTo2GStnFIFCAAEAQf/0AeUCCwAXAEcAsgYAACuyCQAAK7EABOkBsBgvsA/WsRIF6bASELECASuxBQXpsAUQtAYFACYEK7AGL7EZASuxEg8RErANObACEbAJOQAwMSUyNREzESM1BiMiLgM1ETMRFB4DAQSJWE49aDFGIxQDWAMMFilAsQEa/fVMWCArQSkcAUb+3CQrLxkQAAEAQf84Aj4CzAAVAF8Asg4AACuxAATpsgAOCiuzQAAGCSuyEgEAK7AKL7QIBAAfBCsBsBYvsBHWsRQF6bAUELELASuwBTKxCAXpsggLCiuzQAgKCSuxFwErsQsUERKwDjkAsQAOERKwDDkwMSUyPgI1ETMRMxUjEQYHIiYnETMRFAEHFyotG1hWrj1fZksCWEcOIkgzAdr8pDgBCkUCaWEBR/65fgAAAAEAQf/zAzgCFwAmAHgAshsAACuwDjOyHgAAK7EABOmyIgEAK7ADM7IHAQArsRcE6QGwJy+wIdaxJAXpsCQQsQMBK7EFBemwBRCwGiDWEbEbBemwGy+xGgXpsAUQsQ8BK7EOBemxKAErsQMkERKwHjmxDxoRErAHOQCxFwARErEFHDk5MDElMjURMxU2MzIeAxURIxE0LgQjIhURIzUGIyImNREzERQWAQSJVTxoMEUkFAVYAQYNFyYailQ9aGNOWCo/sQEcTVgeKT4uHv65ASYaHC8ZHA2x/uRMWHBhAUj+2lNUAAEAQf84AeYCFwAWAEgAshAAACuyBQEAK7IJAQArsQAE6QGwFy+wBNaxAwXptAcFACYEK7ADELEQASuxDwXpsRgBK7EQAxESsAk5ALEAEBESsAc5MDEBIhURIxEzFTYzMh4CFREjETQuAwEjilhPPGk4SyIMWAIMFSoBzLH+HQLUTVglQ0Ap/rkBJiAlMhwUAAIAI/84AewCFwAkADQAigCyIgAAK7QtBAArBCuyBgEAK7IDAQArtCUEACsEK7AQL7QaBAArBCsBsDUvsADWsSgF6bAoELAXINYRsRYF6bAWL7EXBemwKBCxBQErsDAytAcFADEEK7AHELEgBemwIC+xNgErsSAXERK0EAMiJS0kFzkAsSIaERKxFhc5ObElLRESsSAFOTkwMRM0NjMyFzUzERQOBSMiLgM1Nx4BMzI+AzUGIyImEyIGFRQeAjMyNjU0LgIjd2pcO1ECChIiMUovHzA8JxtVBUExKTgfDwM5V2l15TVXGy4tGDhWHS0vAQhznEo//jofKT4qLxwTBRIgOykBLC4UHTsxLUSWAT9gZjtWKhJhaTdSKxUAAQBGAAABGQIMAAUALwCyBAAAK7QBBAArBCuyBQEAKwGwBi+wBNaxAQXpsgEECiuzQAEDCSuxBwErADAxExEzFSMRm37TAgz+NkICDAAAAAABAEH/OAM4AtMAKQB+ALIQAAArsh4AACuxAATpsh4ACiuzQB4bCSuyIgEAK7IIAQArsRcE6bIIFwors0AIBAkrAbAqL7Ah1rEkBemwJBCxAwErsQYF6bAbINYRsRoF6bAGELEQASuxDwXpsSsBK7EDJBESsB45sRAaERKwCDkAsRcAERKxBhw5OTAxJTI2NxEzETYzMh4DFREjETQuAyMiFREjEQYjIiY1ETMRFB4DAQRNOwJUPGkySCITAlgDDBYpHYlVPWdjT1gCCxUqP15TAeP+7FghKkQlHf65ASYjKy8ZEbH+HQETWHBhAUj+2iEiNBsVAAAAAAIAAP84Ah4CGQAZACQAkACyEAEAK7IVAQArtBoEACsEK7ANL7AIM7QOBAArBCuwBjKyDQ4KK7NADQsJK7ADL7QgBAArBCsBsCUvsAvWsA8ysQoF6bIFER0yMjKyCgsKK7NACggJK7ILCgors0ALDQkrsAoQsSIBK7EABemxJgErsSIKERKxAxU5OQCxIAMRErECBTk5sBoRsQASOTkwMQEUBgciJxUhFSEVIzUjNTMRMxU+ATMyHgInIgYVFBYXMjU0JgIedW1RMQE1/stWZGRRCkU7JUhHK+Q0TEU6jUABFmd9BUGoQkxMQgJGQRo0GTdrdlVfSGYDsVZeAAIAI//0AgkCEgATACUASgCyAAAAK7QcBAArBCuyCwEAK7QUBAArBCsBsCYvsAXWsRkF6bAZELEhASuxDgXpsScBK7EhGRESsQsAOTkAsRQcERKxDgU5OTAxBSIuAjU0PgMzMhYVFA4DAyIOAgcUFjMyPgI1NC4CARYrTkwuIDFDPiFthiIxRTsgGzEvHQFdPBsyLxweMDEMGTlwTT5iOyYOkHdEaDokDAHbFCtVOWthFC1VOThTKxQAAAAAAwAq/zgCbwLVACMAKwAyAKoAshkAACuwFDO0IgQAKwQrsCUyshkiCiuzQBkXCSuyIhkKK7NAIh8JK7AjL7AkM7QvBAArBCuwCjKwMC+0CAQAKwQrAbAzL7AD1rQsBQA8BCuzICwDCCu0HwUAJgQrsB8vtCAFACYEK7AsELEXASuxIi8yMrEWBemxCSQyMrAWELEpASu0DgUAPAQrsTQBK7EXLBESsAA5ALEjIhESsA45sTAvERKwAzkwMQEiJjU0PgI7ARUzMhYVFA4DIwcVIzUjIi4DNTMUMxEzETMyNjU0IycUFjM1IgYBA0lhIT1JLz49WWwcKjo3HC1XLw4oOS8hTqBXJUREjeM1NjM4AbFQQyo7Hw3fhmk8XzklDgHHxwUTHTcjSgFu/pJsU6+WLSWdIQABAEb/+AIgAtMAGABKALIAAAArsQsE6bARMrALELQTBAArBCuyCxMKK7NACw8JKwGwGS+wBdaxCAXpsAgQsQ4BK7AUMrERBemxGgErsQ4IERKwADkAMDEXIi4CNREzERQWMzI2PQEzETMXIzUOAtgrPh0MViUqR0hWTwGjHBs+CB4tIw0CYP3ILStLRJL+4EJSJBwaAAAAAAIAWgAAAL4CBwADAAcAMwCyBAAAK7QFBAAeBCuwAC+0AQQAHgQrAbAIL7AE1rAAMrEHBemwAjKxAwXpsQkBKwAwMRM1MxUDNTMVWmRkZAGiZWX+XmRkAAABAAwApgEmAQcADgAqALAML7QHBAAfBCsBsA8vsA7WtAoFAAgEK7EQASsAsQcMERKxCg45OTAxEx4FFzI3FwYHIic6AhcIGBMeEScwGkFVK1kBBwEPBQsFBQEPICIDFQABADwAAQLBAtkAKACCALIbAwArsQ8E6bADL7AnM7QEBAAfBCuwJTKyAwQKK7NAAwEJK7AHL7ETIzMztAgEAB8EK7AhMgGwKS+wFNaxEwXpsBMQsQEBK7EFCTIysQAF6bEgJDIysgABCiuzQAAnCSuwIjKyAQAKK7NAAQMJK7AHMrEqASuxARMRErAbOQAwMSUjNSM1MzUjNTM1NC4CJyIGHQEjNTQ+AzMyHgIdATMVIxUzFSMCb19cXFxcDCNLOnJPXwcgOG1MU3E9GlJSUlIB4DY5Nhg4SEMiAXB2UVIvRl48KytWbUwZNjk2//8BCf8AAVD/xBAmBNsAgxAGBNsAAAAA//8AcP8AAdT/xBAnBNv/ZwAAECYE27GDECYE2/QAECcE2wCE/4MQBwTbAIQAAAAA//8AeP8AAc//xBAmBNd/ABAGBN69AAAA//8AgP8HAdL/xBAmBN/CABAnBNsAgv+KEAcE2wCCAAAAAQEJ/30BUP/EAAMAKgCwAy+0AAQANwQrtAAEADcEKwGwBC+wA9a0AgUAGwQrtAIFABsEKwAwMQUzFSMBCUdHPEcAAP//AMj/fQGR/8QQJgTbQQAQBgTbvwAAAP//ALj/AAF//8QQJgTb74MQJgTbrwAQBgTbLwAAAQC7/30Bn//EAAMAJACwAy+0AAQANwQrtAAEADcEKwGwBC+xAwErtAIFAAkEKwAwMRczFSO75OQ8RwAAAQC+/wgBov/EAAcAQACwBC+wADO0BQQANwQrsgQFCiuzQAQCCSsBsAgvsALWtAEFABsEK7IBAgors0ABBwkrsgIBCiuzQAIECSsAMDEFFSM1IzUzFQFTRk/kg3V1R0cAAQEIApQBTwLbAAMAMQCyAAMAK7QDBAA3BCuyAAMAK7QDBAA3BCsBsAQvsAPWtAIFABsEK7QCBQAbBCsAMDEBMxUjAQhHRwLbRwAA//8ACAKSAE8C2RAHBOz/CQMVAAD//wCi/u8BsP/EECcE2wBg/3IQJgTb/LkQBgTbmQAAAP//AOABDgEnAVUQBwTb/9cBkQAAAAEA5f8IASz/xAADACMAsAIvtAMEAAsEKwGwBC+wAta0AQUAGwQrtAEFABsEKwAwMQUVIzUBLEc8vLwAAAEAJgIMAYkCWAADABoAsgEBACuxAgTpsgEBACsBsAQvsQUBKwAwMQEhNSEBif6dAWMCDEwAAAAAAQBlApQBVQLbAAMAKwCyAAMAK7QDBAA3BCuyAAMAK7QDBAA3BCsBsAQvsQMBK7QCBQAJBCsAMDETMxUjZfDwAttHAAABAD7/nACVArwAAwAcALIBAgArAbAEL7AA1rEDBemxAwXpsQUBKwAwMRcRMxE+V2QDIPzgAAAAAAECfwKAAsYCxwADACoAsAMvtAAEADcEK7QABAA3BCsBsAQvsAPWtAIFABsEK7QCBQAbBCsAMDEBMxUjAn9HRwLHRwD//wBGAoAAjQLHEAcE6P3HAAAAAP//AFAAAAC4AgwQAgAdAAD//wGKAoAB0QLHEAcE6P8LAAAAAAABAP//fQFG/8QAAwAqALADL7QABAA3BCu0AAQANwQrAbAEL7AD1rQCBQAbBCu0AgUAGwQrADAxBTMVIwD/R0c8RwAAAAEAMwAAAUYCWAALADYAsggAACuxBQTpsgEBACuxAATpAbAML7AI1rEFBemyBQgKK7NABQAJK7NABQcJK7ENASsAMDEBFSIGFREzFSERNDYBMlZSvP7tjgJYTFo+/thMAXpegP//AL7/CAGi/8QQBgTfAAAAAQA6AAACRgJYABcAMwCyDAAAK7AEMwGwGC+wDNaxCwXpsAsQsRUBK7EABemxGQErsRULERKzBQMQEiQXOQAwMQEUBgcXIwMOAh0BIzU0NjcnMxM2PQEzAj5RO5Rm5BEmLFdQPJRm5GNXAb9EgifSAUULJ1cvjZBIhijS/rtKZZYAAAAAAQA6AAACNgJYABEAQQCyDwAAK7EQBOmwDDKyBAEAK7EFBOkBsBIvsBHWsQwF6bIMEQors0AMDgkrshEMCiuzQBEECSuwDzKxEwErADAxATQmKwE1MzIeAhURMxUhNSEBlWFvi5FRdj4cSv4EAVsBc0NWTChDSin+0kxMAAEAHgAAAbECWAATAH8AsgIAACuxEhMzM7IKAQArsQsE6QGwFC+xFQErsDYausCR94QAFSsKsBMuDrAFwAWxEhP5DrARwLAFELMABRMTK7MEBRMTK7IEBRMgiiCKIwYOERI5sAA5ALMABAURLi4uLgG1AAQFERITLi4uLi4usEAaAQCxCgIRErADOTAxJQcjNzMnLgMjNTIeAxcTIwFCr3XPURYHM0czGBc2VEM4BzJYrKzLpzJDHAlMBxssVjn+hQAAAAABACYAAAIfAlgABwA6ALICAAArsgQBACuwADOxBQTpAbAIL7AC1rEBBemyAQIKK7NAAQcJK7ICAQors0ACBAkrsQkBKwAwMQERIxEhNSEVAcxX/rEB+QIM/fQCDExMAAACAD8AAAI6AlgACwAPADoAsgwAACuwBDOyCgEAK7ELBOkBsBAvsAzWsAoysQ8F6bAPELEFASuxBAXpsREBKwCxCgwRErANOTAxAR4BFxEjES4BJyM1GQEzEQFAe2wTVxBBWvlXAlgQYW3+hgF0UToNTP2oAXf+iQABAD4AAACVAlgAAwAcALIAAAArAbAEL7AA1rEDBemxAwXpsQUBKwAwMTMRMxE+VwJY/agAAQAnAAABKAJYAAcAOgCyAgAAK7IEAQArsAAzsQUE6QGwCC+wAtaxAQXpsgECCiuzQAEHCSuyAgEKK7NAAgQJK7EJASsAMDETESMRIzUhFdVXVwEBAgz99AIMTEwAAAAAAQA/AAACOwJYAA0ALwCyBgAAK7AMM7IEAQArsQcE6QGwDi+wBtaxBQXpsAUQsQ0BK7EMBemxDwErADAxATQmKwERIxEhMhYVESMB5GFKo1cBAVyfVwF0PVv99AJYfWH+hgAAAAEAPQAAAjoCWAAdAE0AshUAACuxAATpsgcBACuxDgTpsBkyAbAeL7AY1rEbBemwGxCxAwErsRIF6bEfASuxAxsRErILDhU5OTkAsQcAERKwCzmwDhGwDDkwMSUyNj0BNCYjIgYPATU2MzIWHQEUBiMiJjURMxEUFgE8TVpeSw4nDAwqJm+OkmxmmVdgTFo+kD9ZCgUFUg56ZJxbg4RaAXr+jDVjAAAAAAEAOgEeAJECWAADACEAsAMvtAAEAAcEKwGwBC+wA9axAgXpsQIF6bEFASsAMDETMxEHOldXAlj+6SMAAAEAJv84AdoCWAALABwAsgoBACuxCwTpAbAML7AF1rEEBemxDQErADAxEzIWFREjETQmKwE14GmRV2FKsgJYhVn9vgI8QVdMAAEAOQAAAgQCWAATACUAsg4AACuxDwTpsgQBACuxBQTpAbAUL7AT1rEKBemxFQErADAxATQmKwE1MzIWHQEUBisBNTMyNjUBrXVbpL9soKVixKRcdAFzRFVMhlicW4NMVkMAAAABACUAAAIhAu0AGABUALIJAAArshQBACuxFwTpshcUCiuzQBcVCSsBsBkvsBTWsRcF6bAXELEJASuxCAXpsAgQsRIBK7EABemxGgErsRIIERKxBA45OQCxFAkRErAEOTAxARQOAgcGHQEjNTQ+Ajc+AT0BITUzFSECIScuMgYbVyUsNAgSCf5bVwGlAb81VissDSpiRD9SbigqERtANRrhlQAAAAIAPwAAAjsCWAAGAA0AMACyBQAAK7ENBOmyDAEAK7EGBOkBsA4vsAXWsQ0F6bANELEHASuxBAXpsQ8BKwAwMQEyFhURIREBETQmKwERARh3rP4EAaV4VIICWH9f/oYCWP30AStAVf5AAAAAAAEAMAAAAjoCWAARAGcAsg8AACuxBQYzM7EQBOmyCAEAK7EEBzMzsQkE6QGwEi+wEdaxDgXpshEOCiuzQBEPCSuxEwErsDYauj+d+PYAFSsKsAYusAQusAYQsQUT+bAEELEHE/kDswQFBgcuLi4usEAaADAxATQmKwEDIxMjNTMyFhURITUzAeN1V0E6WDpO53uo/tbTAXdBVP30AgxMgWD+iUwAAQA+/zgAlQJYAAMAFwABsAQvsADWsQMF6bEDBemxBQErADAxFxEzET5XyAMg/OAAAQAzAAABRgJYAAsANgCyBQAAK7EGBOmyCwEAK7EABOkBsAwvsAfWsQQF6bIHBAors0AHAAkrs0AHBQkrsQ0BKwAwMRMyFhURITUzETQmI0dxjv7tvFJWAliAXv6GTAEoPloAAAIAPQAAAjkCWAAKABYAOgCyAQAAK7ETBOmyDwEAK7EEBOkBsBcvsAPWsRAF6bAQELEWASuxCQXpsRgBK7EWEBESsQEAOTkAMDEgIiY1ESEyFh0BFAM0JisBERQWMzI2NQGo2pEBAXSHV1dUo1dQTFuDWwF6dmiccgEISk7+2D5aWT8AAAEAJP/JAhMCWAAVAH8AAbAWL7AL1rEOBemxFwErsDYaug/fwgAAFSsKDrAVELAEwLEUFPmwE8C6wY7x+QAVKwoOsAEQsADAsQIT+bADwLEBAAiwFRCzABUEEyuzAxUEEysAtwABAgMEExQVLi4uLi4uLi4BtwABAgMEExQVLi4uLi4uLi6wQBoBADAxNwMzEzc+BTcRMxEOAwcFN814WXMPHyMgDRAGB1cKEytDOv7WAUMCFf4ABA0QGA0mGyEBWP6iNTo5JxZMTwAAAAEAOf84AgsCWAAUADkAsgQBACuxDgTpsAsvsQgE6QGwFS+wDdaxBQXpsgUNCiuzQAUKCSuwBRCxFAErsRMF6bEWASsAMDEBNCYrARUUFjsBFSMiPQEzMhYVESMBtE5deSxAIii91359VwF0VER/MR1Mk9Jza/2+AAEAPwAAAhUCWAAqAEgAsg0AACuxDgTpshwBACuxKgTptCMgDSoNK7EjBOkBsCsvsCnWsA0ysR0F6bAdELEUASuxBwXpsSwBK7EUHRESsSEiOTkAMDETMh4DHQEUDgIrATUzMj4CPQE0LgMrARUUFjsBFScuBD0B9EFqPSoPKEdxQbWvPFgpEwkcK04yWC89IigcKjglGgJYJTZBMRGcIkxELEwlNi0Rjg0gLiQafy0hTAEBBREeNybSAAAAAQAN/zgB5QJYABEAJgABsBIvsAXWsQQF6bAEELEPASuxAAXpsRMBK7EEBRESsAk5ADAxAQ4BBxEjEQMzEz4ENzUzAeUNW1VXxGOlFg8jEhcIVwG+S2MH/i8B6gE2/vwCAg0WKx+TAAABADMAAAIVAlgAEAAcALIFAAArsQYE6QGwES+wDtaxAAXpsRIBKwAwMQEUBgcTITUhATMTPgI9ATMCDGY8q/4mAUb+smSlHDAtVwG+QGoH/vNMAgz+/QMSNCeTAAIAPv84AiYCWAARABUARQCyDwEAK7EQBOmwBC+xBQTpAbAWL7AU1rAPMrETBemwExCxDQErsQAF6bEXASuxDRMRErEDBDk5ALEPBRESsRIVOTkwMQEOAQcjNTM+BTcRITUhBREjEQImEmx8PjckNSMVDwUF/m8B6P5vVwD/bGIQTAUPGRMpFBsBB0yu/Y4CcgAAAAABACUAAAHvAlgACwAhALIFAAArsgoBACuxCwTpAbAML7AF1rEEBemxDQErADAxEzIWFREjETQmKwE19HWGV09cyAJYdWn+hgF0TkpMAAAAAAEAPAAAAtACWAAdAEcAshcAACuxDATpsAkvsR0E6QGwHi+wGtaxHQXpsB0QsQIBK7EFBemwBRCxEAErsRMF6bEfASuxAh0RErAJObAFEbAWOQAwMRM2NzUzFRQGKwEeATsBMjY1ETMRFAYHIy4BNREzEfZiAldwRmQNeD5XQoZXpntSfaRXASwEWc/TR144XG5MAVL+qVimAwOkWgFX/tQAAAAAAQAjAAACewJYABQAQQCyBwAAK7ATM7EIBOmyDQEAK7ACM7EOBOkBsBUvsAvWsQQF6bILBAors0ALBwkrsAQQsRQBK7ETBemxFgErADAxATQrAREUBiM1MjY1ESM1ITIWFREjAiSraXR5TUk8AQN5glcBdJj+1HVrTERNAS9McW3+hgAAAgA+AAABagJYAAMABwAmALIEAAArsAAzAbAIL7AE1rEHBemwBxCxAAErsQMF6bEJASsAMDEhETMRIREzEQESWP7UWAJY/agCWP2oAAIAPAAAAV8CWAADAAcAIwCyBAAAKwGwCC+wA9axAgXpsAIQsQQBK7EHBemxCQErADAxEzMTBxMRMxE8VwFYzFcCWP7pI/7iAlj9qAACADgBHgFXAlgAAwAHAC4AsAcvsAMztAQEAAcEK7AAMgGwCC+wB9axBgXpsAYQsQMBK7ECBemxCQErADAxATMRBwMzEwcBAFdXyFcBWAJY/ukjATr+6SMAAQAsAdAAiQLFAAUAOgCyAAIAK7QEBAAJBCsBsAYvsAXWsQIF6bECBemzAwIFCCu0BAUAEQQrsAQvtAMFABEEK7EHASsAMDETMxUHIycsXRsnGwLFb4aGAAIANwHQATQCxQAFAAsAXgCyAAIAK7AGM7QEBAAJBCuwCTIBsAwvsAXWsQIF6bMDAgUIK7QEBQARBCuwBC+0AwUAEQQrsAIQsQsBK7EIBemzCQgLCCu0CgUAEQQrsAovtAkFABEEK7ENASsAMDETMxUHIyc3MxUHIyc3XRsnG6BdGycbAsVvhoZvb4aGAAAAAAQAOAACAjcB+AALABcAIgAtAHAAsAYvtAAEABIEK7ASL7AeM7QMBAASBCuwGDKwKS+0JAQAEgQrAbAuL7AV1rQPBQAkBCuwDxCxCQErsCwytAMFACQEK7AmMrADELEhASu0GwUAJAQrsS8BK7EDCRESsSMpOTkAsQwSERKxGyE5OTAxJTIWFRQGIyImNTQ2JzIWFRQGIyImNTQ2JDIWFRQGIyImNTQmMhYVFAYjIiY1NAFAFiIgGBYhILoWIiAYFiEgAZAuISEXFiGhLiEgGBYhcSAYFiEgFxYixCAYFiEgFxYiASAYFiIhFxbkIBgWISAXFgABADQAYwCjANIACwAuALAGL7QABAASBCu0AAQAEgQrAbAML7AJ1rQDBQAkBCu0AwUAJAQrsQ0BKwAwMTcyFhUUBiMiJjU0NmsWIiAYFiEg0iAYFiEgFxYiAAAAAAEAMv+QAKH//wALAC4AsgAAACu0BgQAEgQrsgAAACsBsAwvsAnWtAMFACQEK7QDBQAkBCuxDQErADAxFzIWFRQGIyImNTQ2aRYiIBgWISABIBgWISAXFiIAAAAAAgAzAGQAogHEAAoAFgA3ALAGL7QBBAASBCuwES+0CwQAEgQrAbAXL7AJ1rAUMrQDBQAkBCuwDjK0AwUAJAQrsRgBKwAwMTYyFhUUBiMiJjU0EzIWFRQGIyImNTQ2Uy4hIBgWITcWIiAYFiEg0yAYFiEgFxYBEyAYFiEgFxYiAAACACz/EACcAHAACwAXAEEAsAYvtAAEABIEK7ASL7QMBAASBCsBsBgvsAnWsBUytAMFACQEK7APMrQDBQAkBCuxGQErsQMJERKxDBI5OQAwMRcyFhUUBiMiJjU0NjcyFhUUBiMiJjU0NmQWIiAYFiEgFxYiIBgWIiGBIBgWISAXFiLxIBgWISAXFiIAAAIAagABAYoAcQALABcARQCwEi+wBjO0DAQAEgQrsAAytAwEABIEKwGwGC+wFda0DwUAJAQrsA8QsQkBK7QDBQAkBCuxGQErALEMEhESsQMJOTkwMSUyFhUUBiMiJjU0NicyFhUUBiMiJjU0NgFSFiIgGBYhIJoWIiAYFiEgcCAYFiEgFxYiASAYFiEgFxYiAAIAav+SAYoAcQALABcAOACwBi+0AAQAEgQrsBIvtAwEABIEKwGwGC+wFda0DwUAJAQrsA8QsQkBK7QDBQAkBCuxGQErADAxJTIWFRQGIyImNTQ2JzIWFRQGIyImNTQ2AVIWIiAYFiEgmhYiIBgWISABIBgWISAXFiJwIBgWISAXFiIAAAIAav+TAYoAcAALABcARQCwBi+0AAQAEgQrswwABggrtBIEABIEKwGwGC+wFda0DwUAJAQrsA8QsQkBK7QDBQAkBCuxGQErALEADBESsQMJOTkwMSUyFhUUBiMiJjU0NgcyFhUUBiMiJjU0NgFSFiIgGBYhIJoWIiAYFiEgcCAYFiEgFxYibiAYFiEgFxYiAAIAVABhATUBwgALABYAOACwBi+0AAQAEgQrsBIvtA0EABIEKwGwFy+wFda0DwUAJAQrsA8QsQkBK7QDBQAkBCuxGAErADAxNzIWFRQGIyImNTQ2JjIWFRQGIyImNTT+FiEgFxYiIXMuISAYFiHQIBgWISAXFiLyIBgWISAXFgAAAgBX/w8BOQBwAAsAFgA4ALAGL7QABAASBCuwEi+0DQQAEgQrAbAXL7AV1rQPBQAkBCuwDxCxCQErtAMFACQEK7EYASsAMDEFMhYVFAYjIiY1NDYmMhYVFAYjIiY1NAEBFiIgGBYhIHMuISAYFiGCIBgWISAXFiLyIBgWISAXFgAFABoAAwIkAsgACgAWACIALgAyAJsAsjIBACu0MQQAQgQrsB0vtBcEABIEK7ApL7QjBAASBCuwES+wBjO0CwQAEgQrsAAyAbAzL7Ag1rAsMrQaBQAkBCuwJjKzDhogCCu0FAUAJAQrsBQvtA4FACQEK7MJGiAIK7QDBQAkBCuxNAErsSAUERKxEQs5ObEJDhESsxcdIykkFzmxAxoRErEABjk5ALELERESsQMJOTkwMQAyFhUUBiMiJjU0JzIWFRQGIyImNTQ2EzIWFRQGIyImNTQ2NzIWFRQGIyImNTQ2JRUhNQFiLiEhFxYheRYiIBgWISBuFiIgGBYhIBcWIiAYFiEgARv99gLIIBgWIiEXFiEgGBYhIBcWIv2rIBgWISAXFiLwIBgWISAXFiKqXFwAAgAaAPUCJAIMAAoADgAsALIOAQArtA0EAEIEK7AGL7QBBAASBCsBsA8vsAnWtAMFACQEK7EQASsAMDEAMhYVFAYjIiY1NCUVITUBCS4hIBgWIQE7/fYBZCAYFiEgFxbKXFwAAAEAiACxAeACbQAGAAABNwcnNwM3AbAwGIwy5k0BEB9+GB4BWS0AAAAFABoA5AIkAtIACQATAB0AJwAzAKMAsigBACuwLDO0MwQAQgQrsC4ysjMoCiuzQDMxCSuyKDMKK7NAKCoJK7AlL7AbM7QhBAASBCuwFjK0EQ0oKg0rsAIztBEEABIEK7AHMgGwNC+wHtawCjK0IwUAJAQrsA4ysCMQsTEBK7ApMrEwBemwKzKyMDEKK7NAMC4JK7IxMAors0AxMwkrsDAQsRQBK7AAMrQZBQAkBCuwBDKxNQErADAxATQ2MhYUBiMiJiU0NjIWFAYjIiYBNDYyFhQGIyImJTQ2MhYUBiMiJiczNTMVMxUjFSM1IwGPHjIfHxkYH/62HjIfHxkYHwFKHjIfHxkYH/62HjIfHxkYHyvWZc/OZdcCbRkfHzIeHxgZHx8yHh/+9RkfHzIeHxgZHx8yHh/axsZczMwAAQAj/3cBnwJ6ABQAMwCyEgAAK7EPBOkBsBUvsATWsQ0F6bINBAors0ANEAkrsRYBK7ENBBESsgoPEjk5OQAwMRc+AjU0LgInMx4BFRQHMxUjBgcjEzpEFSEVClUgOxur3CEsiRtqzVdIgVYsDyyfPE/KWk47AAAAAQA5AXQBggMyABIANACwBy+xBATpAbATL7AQ1rQCBQAxBCuyAhAKK7NAAgYJK7EUASuxAhARErIABAc5OTkAMDETFhcUBzMVIw4DByM+ATU0J74qFQeMvQEJBhYTUypJQwMyNV5NMloDFwgcFCyJTXVHAAAB/7gAAAIaAasABwA0ALIBAAArsQIE6bAFL7EGBOkBsAgvsAPWsQAF6bIDAAors0ADAQkrs0ADBQkrsQkBKwAwMSkBNSE1ITUhAhr9ngIE/twBglr5WAAAAf+4/xkCYQIdAB8AWQCyCgAAK7ARM7ELBOmwDzKyGgAAK7ADL7QdBAApBCsBsCAvsAbWsQAF6bIGAAors0AGCwkrsSEBK7EABhESswgPFxskFzkAsR0DERKwCDmxCwoRErAYOTAxBRQGIyImNTQ3JyE1IQE3ATMVIyIuAjUnBgcXNjMyFgILGxMbHBl0/m0Bpv77TQEMrzgaIyYTGBMnZgoFGRyyFh8cFhkPjVoBli3+PVoDCRYQBh8jfQIaAAAAAf+4/xkCYQIdACAAWwCyCgAAK7AUM7ELBOmxDhIyMrIcAAArsAMvtB8EACkEKwGwIS+wBtaxAAXpsgYACiuzQAYLCSuxIgErsQAGERKzCBIZHSQXOQCxHwMRErAIObELChESsBo5MDEFFAYjIiY1NDcnITUzNwczATcBMxUjIi4BNScGBxc2MzICCxoUGR4ZdP5t1GIomP77TQEMrzkjLCYYEydmCgU1shYfHRUTFY1ampoBli3+PVoFFxYGHyN9AgAAAAIAa/9xAdkBrQADABIATACyCwAAK7EMBOmwAS+xAgTpsBIvsQQE6QGwEy+wAda0AAUAGQQrsAAQsQ0BK7QKBQAbBCuyDQoKK7NADQsJK7NADRIJK7EUASsAMDEXIzUzAzIeAhURITUhNTQuASPxeXlCXG9GGf6SASgiXWWPUwHpCx8xKf7XWnk4MxUAAQBrAAAB2QGtAA4ANwCyBwAAK7EIBOmwDi+xAATpAbAPL7AJ1rQGBQAbBCuyCQYKK7NACQcJK7NACQ4JK7EQASsAMDETMh4CFREhNSE1NC4BI69cb0YZ/pIBKCJdZQGtCx8xKf7XWnk4MxUAAgBt/7sChQGtABEAHQBgALIAAAArsRIE6bANL7AYM7QIBAA2BCsBsB4vsAXWtBsFABsEK7AbELEVASu0DwUAGwQrsA8QsQsBK7EKBemxHwErsRUbERKwADmwDxGwDTkAsQ0SERKzBQ8VGyQXOTAxBSIuAjU0NjMFESMRIxYVFAYnMjY1NCYjIgYVFBYBGREyPitfVQFkWYMKSVAmNDQqJj45AhEnWDxfhAL+EAGULEVle09JMTRYWSs2TAACAGQAAAIaAasACwAVAEIAsgAAACuxEgTpsA0vsQYE6QGwFi+wA9axDwXpsA8QsRUBK7EJBemxFwErsRUPERKxBgA5OQCxDRIRErEJAzk5MDEhIiY1NDYzMhYVFAYCIgYVFBYzMjY0AUBienxgYXl7MWJOUTQzSn5XWnx9WVt6AVFLLzJLSGIAAQCx/1YBWwFzAAwAHQABsA0vsAPWtAgFAAwEK7QIBQAMBCuxDgErADAxBS4BNTQ2MzIVFA8BJwEeSyIyWCAFQjoGgF8yQCjPL32iEAAAAAAB/7gAAAJPASIADgBTALIHAAArsQADMzOxCATpAbAPL7AJ1rQFBQARBCuyCQUKK7NACQcJK7AFELELASu0AgUAEQQrsRABK7ELBRESsAQ5sAIRsA05ALEIBxESsAs5MDEhIycVIycVITUzNRc0NxcCTyR/Snr+0PjDBtZwcHNzWr3DXHLBAAAAAv+4/18CqgIcAAkADAAlALIDAAArsAozsQQE6bAIMrIAAAArsgcBACsBsA0vsQ4BKwAwMQUHJyE1IQE3ATMHIxcCqq9f/hwBtP7wSgEQ9C6mRAeaoVoBliz+PlpfAAAAAf+4/18CqgIcAAkAIgCyAwAAK7EEBOmwCDKyAAAAK7IHAQArAbAKL7ELASsAMDEFBychNSEBNwEzAqqvX/4cAbT+8EoBEPQHmqFaAZYs/j4AAAAAAf+4AAABwAERAAcAHwCyAwAAK7EEBOkBsAgvsQkBKwCxBAMRErEABzk5MDElJwchNSE1FwHAagf+aQFloxFPYFq3wQAG/7L/UwL1AwAACwAXACMALwA7AFQA/gCyTQAAK7RGBABCBCuyPAAAK7EwBOmwBi+0AAQAEgQrsFAvsDYztEQEADYEK7ASL7AeM7QMBAASBCuwGDKwKi+0JAQAEgQrAbBVL7BB1rQ5BQAbBCuwORCxFQErtA8FACQEK7APELEzASu0UgUAGwQrsxszCQ4rsC0ztAMFACQEK7AnMrBSELFOASuxRgXpsxtGTggrtCEFACQEK7AhL7QbBQAkBCuxVgErsQkVERK0DBIwNjwkFzmxUjMRErQGJCoAUCQXObFOAxESsRgeOTmxRhsRErBNOQCxAAYRErBOObEwPBESsEo5sEYRsEk5sFAStTNBOUhLUiQXOTAxFzIWFRQGIyImNTQ2AzIWFRQGIyImNTQ2MzIWFRQGIyImNTQ2JzIWFRQGIyImNTQ2AzI2NTQmIyIGFRQWFyIuAjU0NjMFEzM1FxUnByMHESMWFRQG3hYiIBgWISBLFiIgGBYhINsWIiAYFiEgSxYiIBgWISBoJjQ0KiY+OS4SMj4qX1UBZAKGo2oHuFuDCkk+IBgWISAXFiICsiAYFiEgFxYiIBgWISAXFiKMIBgWISAXFiL9TkkxNFhZKzZMTxIpVjtfhAL+sLfBP09iRAGULEVlewAAAAABAGH/KAIlAdsAEgAlALAFL7EOBOkBsBMvsAPWtBEFACYEK7EUASsAsQ4FERKwDDkwMQUjNjU0IyIHAyUVBRc2MzIWFRQB11pcQER0gAFh/v5FXEk7QNiVV0hPAV1xWlW0O0lAbgAAAAH/uAAAAnACmAAGABUAsgEAACuxAgTpAbAHL7EIASsAMDEpATUhATcBAnD9SAJm/lVKAbNaAftD/c0AAAIAa/92AoUBqwAHAAsAOgCyAQAAK7ELBOmwBS+wCTOxBgTpAbAML7AI1rQABQAmBCuyCAAKK7NACAMJK7NACAUJK7ENASsAMDEpAQcjEyM1IQM1IwcChf6RPVO92AIaT59eigHdWP6v+fkAAAEAa/7UAnABAwAFABEAsgUAACsBsAYvsQcBKwAwMT8BAQcBB2tzAZIo/uM8nmX99CMBYzcAAAAAA/+4//4CsQGoABkAJgAzAJ4AshMAACuxFATpsg4AACuxGgTpsCcvtAAEADcEK7MIACcIK7EfBOkBsDQvsBfWtCoFABsEK7IXKgors0AXEwkrsCoQsTIBK7QlBQARBCuwJRCxHAErtAsFABEEK7E1ASuxKhcRErAVObAyEbIAEhE5OTmxHCURErIGCA45OTkAsRQaERKxESU5ObAfEbULFxwqLzIkFzmwJxKwBjkwMQEyHgEXFhc2MzIWFRQGIyImJxUhNSEmNTQ2ATI1NCYjIgYHDgEVFgMiBhUUHgIXPgE1NAE1KTodEwMCNS1BQVNYRGZt/skBFyhKAR5qNyYaJBQICyKdJi8VLigjCRIBqBkfHAUDI3hPYUkfOFVaLV9oWv6oWStNIB8QWSAJARA6MSAwIxUOF2AcbgAAAAMAp/8yArEBqAAaACoAOACKALIOAAArsRsE6bArL7QABAA3BCuzCAArCCuxIwTpAbA5L7AY1rQuBQAbBCuwLhCxNgErtCkFABEEK7ApELEgASu0CwUAEQQrsToBK7EuGBESsBQ5sDYRsxATABUkFzmxICkRErIGCA45OTkAsRsOERKxEBU5ObAjEbQYCy4zNiQXObArErAGOTAxATIeARcWFzYzMhYVFAYjIicGDwEnNy4BNTQ2ATI+AjU0JiMiBgcOARUWAyIGFRQeAhc+ATU0JgE1KTodEwMCNS1BQVdUUycKImRImkRjQAEoCx4nGjcmGiQUCAshnCYvFS4oIwkSKgGoGR8cBQMjeE9fSgUeLoYytBJpU11l/qgHESYbK00gHxBZIAkBEDoxIDAjFQ4XYBw0OgAAAAH/uAAAAqQCHAAUADQAsgcAACuxCgTpsBIysAoQsQIE6bIOAQArAbAVL7EWASsAsQoCERKwADmwDhGxBRQ5OTAxJQYjIiYnBgchNSUyNwM3Ex4BMzI3AqRrRjNDGyQG/oABJjgs3EG8KEUsPFNLPjcxRDFaASkBbSv+wD5DSwAAAv+4AAACHAJAAA0AFgAxALIJAAArsQoE6bAAL7QUBAA3BCsBsBcvsAPWtBEFADEEK7EYASsAsRQAERKwDDkwMSUiJjU0Nj8BEyE1IScGNw4BFRQWMzI3AVNkVkY5xT/9nAIKDD4icEEwKEYp5U9MOEYPM/3AWpEG8xghLiIkCAAC/7gAAAIcAkAADAAYAJgAsgkAACuxBgTpsAMvtA8EADcEKwGwGS+wEta0AAUAMQQrsRoBK7A2Grrv9sILABUrCg6wGBCwFcCxCgT5sAzAswsKDBMrsBgQsxYYFRMrsxcYFRMrsgsKDCCKIIojBg4REjmyFxgVERI5sBY5ALUKCxcYFRYuLi4uLi4BtQoLFxgVFi4uLi4uLrBAGgEAsQ8DERKwBTkwMQEUBiMiJwchFSETFxYFFjMyNjU0Jy4BLwEBO1ZkJT4MAgr9nD/Ff/7pKUYoMB4FSiIiAYBMTwaRWgJAMyqwCCQiJBsFFAcIAAABAH/+1AKCARAAIgBNALIUAAArsQ0E6bIaAAArsAEvsQIE6QGwIy+wB9axGQXpsSQBK7EZBxESsgIBCTk5OQCxAgERErAfObAUEbAdObANErMQERcZJBc5MDEBITUhJicmNTQ3HgIXMzUXFScHIyImJwYVFB4DFRQGBwJp/ikBZJE0shsHNi8IoqJpCawjJQwEV3x8VwoI/tRaKRZLeF+BClNJELTCPk9dEhYECiI9LCgsFgghFAAAAv+4AAACJgGrAAsADwBYALIGAAArsAAztAcEAB4EK7AMMrAOL7EJBOkBsBAvsAjWtA8FACYEK7IIDwors0AIBwkrsA8QsQwBK7QLBQAbBCuxEQErsQ8IERKwAzkAsQcGERKwAzkwMTMiJicHFSM1MxEhESc1IxXzDkAGGc7gAY5G/TUQBEFkAUf+VWTv7wAAAgBrAAAB2QJgAAMAEwBSALILAAArsQwE6bIBAQArsQIE6bQEEwsCDSuxBATpAbAUL7AB1rQABQAZBCuwABCxEAErtAkFABsEK7IQCQors0AQCwkrs0AQEwkrsRUBKwAwMQEjNTMHMh4CFREhNSE0NjU0JiMBHXt7blxvRhn+kgEoAlSSAg5SswsfMSn+11oNYQtRLwAAAAAB/7gAAAKFAasADwBkALIFAAArsAAzsQYE6bAOMrAJL7AMM7EKBOkBsBAvsAfWsQ4F6bIOBwors0AODwkrsAcQsAgg1hGxDQXpsggNCiuzQAgGCSuzQAgJCSuxEQErsQ0HERKwAzkAsQYFERKwAzkwMSEjIicHITUhJyM1IRcHFzMChc0vFRj+XAGwCsgBwQGgCsM7O1r3WlkB9wABAGP/9gJrAesAGQBJALIDAAArsBgztBEEADUEK7ARELAUINYRsQAE6QGwGi+wBta0DwUAGwQrsRsBKwCxAAMRErAMObAREbELFzk5sBQSsQ8GOTkwMSUiBiMiJjU0PgE3ARUBBhUUMzI2MzIWFwcmAVwKbhI2OUtOKAFH/q9uKh5pChQ6FCgdKC9DOUWiZSr+bFMBiMBKKis5GzkmAAAAAf+4AAACGgJ0AAsANwCyAQAAK7ECBOmwBS+xBgTpsAoyAbAML7AD1rEABemyAwAKK7NAAwEJK7NAAwUJK7ENASsAMDEpATUhNSE1MzcXByECGv2eAgT+3AzHJJYBIVr5WMkeqwAAAAAB/7j/GQJhAi4ALwCMALIgAAArsAczsSEE6bAFMrIQAAArsBkvtBMEACkEK7AEL7QmBAArBCsBsDAvsCnWtAIFABsEK7ICKQors0ACBgkrsCkQsBwg1hGxFgXpshwWCiuzQBwhCSuxMQErsRwpERKwDjmwAhG0AAUNER4kFzmwFhKxExk5OQCxExkRErAeObEhIBESsA45MDEBFhQGIxczFSMiLgI1JwYHFzYzMhYVFAYjIiY1NDcnITUhATcWMzI2NTQuAi8BAbEXYUSPrzgaIyYTGBMnZgoFGRwbExscGXT+bQGm/vtNWDgeNwQFBgICAi4lcE/wWgMJFhAGHyN9AhoTFh8cFhkPjVoBli2SMBoGEA4NBAQAAwBr/zgB2QGtAAMABwAXAGoAsg8AACuxEATpsAUvsQYE6bMCBgUIK7EBBOmwFy+xCATpAbAYL7AF1rAPMrQEBQAZBCuwBBCxFAErtA0FABsEK7IUDQors0AUFwkrswANFAgrtAEFABkEK7ABL7QABQAZBCuxGQErADAxBSM1MwcjNTMDMh4CFREhNSE0NjU0JiMBont7u3t7OFxvRhn+kgEoAlSSyFIQUgHhCx8xKf7XWg1hC1EvAAIAzgJUAYwDEgAPABIAowCwAS+0BwQACwQrAbATL7AE1rQKBQALBCuwChCxAAErsDYasCYaAbEBAC7JALEAAS7JsDYausJ27msAFSsKDrABELAFwLAAELAQwLAFELMCBQETK7AQELMPEAATK7IPEAAgiiCKIwYOERI5sgIFARESOQCzAgUPEC4uLi4BswIFDxAuLi4usEAaAbEKBBESsgYREjk5OQCxBwERErEDEjk5MDEBBycHJzcnNxc3FwcXBycHJzcnAR8YDSYGJRgaWSgWLCQaIjUHJz0CZBArGB0Wag5BGA8bHhAeIRsXNQAAAAIBAP7UAb3/kgAPABIAnQCwBy+0AQQACwQrAbATL7AK1rQEBQALBCuwBBCxAAErsDYasCYaAbEBAC7JALEAAS7JsDYausJ27msAFSsKDrAQwLABELAFwLMCAQUTK7AAELMPABATK7ICAQUgiiCKIwYOERI5sg8AEBESOQCzAgUPEC4uLi4BswIFDxAuLi4usEAaAbEEChESsgYREjk5OQCxAQcRErEDEjk5MDEFNxc3FwcXBycHJzcnNxc3FwcXAW0YDSYFJBgaWSgWKyMaIjUHKD5+ECsYHRZqDkEXDhseEB4hGhg1AAACASz+9wFPAukAAwAHAB8AAbAIL7AD1rAEMrQCBQARBCuwBTK0AgUAEQQrADAxBTMVIxEzFSMBLCMjIyNzlgPylgAAAAIA9QIqAeADCAADAAcAOwCyAAIAK7ACL7QEBAAJBCsBsAgvsAfWtAEFAAkEK7EBBxESsQMFOTkAsQACERKxBgc5ObAEEbAFOTAxARcHLwEXBycBwh5LHjceSx4CvRKBEc0SgREAAAAAAgDN/vwBuP/aAAMABwAwALACL7QEBAAJBCsBsAgvsAfWtAEFAAkEK7EBBxESsQMFOTkAsQQCERKxAAY5OTAxBRcHLwEXBycBmh5LHjceSx5xEoERzRKBEQAAAAACAOMCNQH4AwAACgAWAEsAsBEvtAsEABIEK7MBCxEIK7QGBAASBCsBsBcvsBTWtA4FACQEK7AOELEJASu0AwUAJAQrALERBhESsQMJOTmxCwERErEOFDk5MDEAMhYVFAYjIiY1NCcyFhUUBiMiJjU0NgGpLiEgGBYhbhYhIBcWIiECpCAYFiEgFxZ+IBgWISAXFiIAAQD1AioB4AMIAAsAHACwCS+0BwQACQQrAbAML7AG1rQIBQAJBCsAMDEBByc3JwcnNxcHJzcBjDghOCA4HkugSx43Aq5eE18TYBGCXYERXwABAM3+/AG4/9oACwAcALAHL7QJBAAJBCsBsAwvsAjWtAYFAAkEKwAwMQU3FwcXNxcHJzcXBwEhOSA4IDgeS6BLHjeqXhNfE2ARgl2BEV8AAAIA3P8fAZX/tQADAAcAMACwBy+wAjO0BAQADgQrsAAyAbAIL7AH1rQGBQARBCuwBhCxAwErtAIFABEEKwAwMQUzFSMnMxUjAXIjI5YjI0uWlpYAAAIAff72AZr/wAADAAcAMACwBi+0AAQACgQrAbAIL7AH1rQBBQAHBCuxAQcRErEDBTk5ALEABhESsQIEOTkwMQUXBy8BFwcnAXweSx5pHkseQBKBEUsSgREAAAAAAQCpAkwBWwLKAAsASACwAC+0AQQAEwQrsAkysAQvsAcztAUEABMEKwGwDC+wAta0CQUAEQQrsgkCCiuzQAkLCSuwBjKyAgkKK7NAAgAJK7AEMgAwMRM1MzUjNTMVIxUzFalISLJJSQJMIjwgIDwiAAEBIP9EAdL/wgALAEgAsAAvtAEEABMEK7AJMrAEL7AHM7QFBAATBCsBsAwvsALWtAkFABEEK7IJAgors0AJCwkrsAYysgIJCiuzQAIACSuwBDIAMDEFNTM1IzUzFSMVMxUBIEhIsklJvCI8ICA8IgABAQf/TwF2/74ACwAqALAGL7QABAASBCu0AAQAEgQrAbAML7AJ1rQDBQAkBCu0AwUAJAQrADAxBTIWFRQGIyImNTQ2AT4WIiAYFiEgQiAYFiEgFxYiAAAAAgCrAjYBewMPAAoAEwAwALAGL7EABOmwDi+0DwQAEwQrAbAUL7AI1rEDBekAsQAGERKwCzmxDw4RErATOTAxEzIWFRQGIiY1NDYXBy8BNTM3Fwf5EhoaJBsalR4vg40rGCsClRkTEhsaExIaVQp5BCE7EjkAAAAAAgD9/wEBzf/bAAoAEwAwALAQL7QNBAATBCuwBi+xAATpAbAUL7AJ1rEDBekAsQ0QERKwEzmxAAYRErALOTAxBTIWFRQGIyImNDYHNx8BFSMHJzcBeRIbGhMSGhlpHy6DjCsZKy0aExIaGiQbAgp3BiI7EzgAAAAAAQEHAmoBdgLZAAsAMQCyAAMAK7QGBAASBCuyAAMAK7QGBAASBCsBsAwvsAnWtAMFACQEK7QDBQAkBCsAMDEBMhYVFAYjIiY1NDYBPhYiIBgWISAC2SAYFiEgFxYiAAAAAQEP/2YBcf/DAAMAJACwAS+0AgQANgQrtAIEADYEKwGwBC+wAdaxAAXpsQAF6QAwMQUjNTMBcWJiml0AAQEHAmoBdgLZAAsAMQCyAAMAK7QGBAASBCuyAAMAK7QGBAASBCsBsAwvsAnWtAMFACQEK7QDBQAkBCsAMDEBMhYVFAYjIiY1NDYBPhYiIBgWISAC2SAYFiEgFxYiAAAAAQEH/08Bdv++AAsAKgCwBi+0AAQAEgQrtAAEABIEKwGwDC+wCda0AwUAJAQrtAMFACQEKwAwMQUyFhUUBiMiJjU0NgE+FiIgGBYhIEIgGBYhIBcWIgAAAAIBCQI3AXgDUAAKABYANQCyEQMAK7QLBAASBCuwBi+0AQQAEgQrAbAXL7AJ1rAUMrQDBQAkBCuwDjK0AwUAJAQrADAxADIWFRQGIyImNTQ3MhYVFAYjIiY1NDYBKS4hIBgWITcWIiAYFiEgAqYgGBYhIBcWzCAYFiEgFxYiAAAAAgEH/tQBd//ZAAsAFwA9ALAGL7QABAASBCuwEi+0DAQAEgQrAbAYL7AJ1rAVMrQDBQAkBCuwDzK0AwUAJAQrsQMJERKxDBI5OQAwMQUyFhUUBiMiJjU0NjcyFhUUBiMiJjU0NgE/FiIgGBYhIBcWISAXFiIhvSAYFiEgFxYiliAYFiEgFxYiAAMApwI3AdoDMgALABcAIwBxALIeAgArtBgEABIEK7AGL7ASM7QABAASBCuwDDIBsCQvsAnWtAMFACQEK7ADELEVASu0DwUAJAQrsxsPFQgrtCEFACQEK7AhL7QbBQAkBCuxIQkRErEGADk5sRUDERKxGB45ObEPGxESsQwSOTkAMDETMhYVFAYjIiY1NDYzMhYVFAYjIiY1NDYnMhYVFAYjIiY1NDbeFiIgGBYhINsWIiAYFiEgSxYiIBgWISACpiAYFiEgFxYiIBgWISAXFiKMIBgWISAXFiIAAAADAKz+1AHV/8oACgAVACEAZQCwHC+0FgQAEgQrsAgvsBMztAMEABIEK7AOMgGwIi+wANa0BgUAJAQrsx8GAAgrtBkFACQEK7AGELELASu0EQUAJAQrsR8AERKxAwg5ObELBhESsRYcOTmxERkRErEOEzk5ADAxFzQ2MzIWFAYjIiY3NDYzMhYUBiMiJgcyFhUUBiMiJjU0NqwiFRchHxkXILoiFRchHxkXICcWIiAYFiEgbhchIDAfIhUXISAwHyI6IBgWISAXFiIAAAABAKoCgAHYAwwAAwAcALADL7QBBAAPBCsBsAQvsADWtAIFAAcEKwAwMRMlFwWqAR4Q/uYCvk4sYAAAAAABAKj/SAHa/+IAAwAcALACL7QABAANBCsBsAQvsAPWtAEFAAcEKwAwMRcFByW6ASAU/uIeUkhmAAEApwI3AdQDIQAjACkAsBQvtAIEAAkEKwGwJC+wCta0CwUAEQQrsQsKERKzDBUWFyQXOQAwMRMXNxcHFzcXBxc3FwcXNxcHFwcnByc3JwcnNycHJzcnByc3J7IeFh8VHhYeFR8UJBYfFyIWJA8kFyMYHhciGB0YHhceGCAXHgLvCTsJOwk7CD4JPwo/CkAKQAwoDUQNQwpDDEMLQgxADEIMQQsABQDVAlYBpQMbAAsAEgAZACAAKQCuALIkAwArsA4ztCcEABMEK7AMMrAfL7AYM7QbBAATBCuwEzKwCy+wBjO0AAQAEwQrsAQysgsACiuzQAsJCSuyAAsKK7NAAAIJKwGwKi+wGtawJTK0HAUAEQQrsCEysBwQsQkBK7ABMrQIBQARBCuwAzKyCAkKK7NACAYJK7IJCAors0AJCwkrsAgQsRMBK7ARMrQVBQARBCuwDDKxFRMRErAOOQCxGx8RErAVOTAxEzM1MxUzFSMVIzUjNhQjIiY1NBYyFRQGIyImMhUUBiMiNxQGIyI0MzIW1VYnU1IpVcEWCA4BLA0JFoUsDQkWLA0JFhYJDQLMT08lUVFnLA0JFnoWCA4tFggOjwkNLA4AAAEAhP/oAtMCIAAGACAAsgYAACuyAgEAKwGwBy+xCAErALECBhESsQMFOTkwMQUBNxsBFwMBif77VODEV+0XAhEi/jsBySL96gAAAAAB/7gAAAJwAsMAFwBXALIIAAArsQkE6bIAAgArshABACu0BQQAHwQrAbAYL7AT1rQCBQAbBCuyAhMKK7NAAgcJK7EZASuxAhMRErAAOQCxBQkRErAGObEAEBESsgILDDk5OTAxARYVFAYHARUhNSEBNx4CMzI2NTQmLwEBwR5PPwEf/UgCZv5VShogQRUiMwwGBQLDJzM8UwL+jWVaAftDIig5MSEJGwkKAAAAAv+4AAACcAKYAAkAGQBgALILAAArsQwE6bAYL7QGBAAfBCuwAS+0EwQAHwQrAbAaL7AJ1rQWBQAbBCuyFgkKK7NAFgoJK7EbASuxFgkRErANOQCxGAwRErAZObEBBhESshAVFjk5ObATEbAOOTAxACIGFRQWMzI2NBMhNSEBNxc+ATMyFhQGBxcB4kQ1OCMiM1f9SAJm/lVKdw9MM0JSTz+oAiMyICMyMUL+EVoB+0OZLDZWeFMC2QAAAP///tECkABHA4QQDwVd/x4GFMAA///+1wKQAE0DhBAmBV79OBAGBaEDAAAAAAH/SwK4/98DTAADABwAsAIvtAAEAA4EKwGwBC+wA9a0AQUADgQrADAxAxcHJ2tKSkoDTEpKSgD//wBMAGIA4AINECcFXgEB/aoQBwVeAQH+wQAA//8AHgAAAtcDXBAnBaICwwAAEAYFYQAAAAEAHgAAAtcCZQA9ANMAsgsAACuyLwEAK7EECDMztDYEAEMEK7AGMrI4AQArtBQfCzYNK7QUBABDBCu0DgALNg0rtA4EACsEK7QpJAs2DSu0KQQAEwQrAbA+L7As1rQ5BQAbBCuzITksCCu0EgUAGwQrsDkQsQsBK7ADMrQKBQAbBCuyCgsKK7NACggJK7ILCgors0ALBQkrsT8BK7EhLBESsDs5sRI5ERKwEDmwCxGxAA45OQCxDh8RErESITk5sAARswwQGSYkFzmwKRKyAxo7OTk5sC8RsjEyOTk5OTAxATI2NzUjNSEVIxEjEQYjIicWFRQjIi4CJzceAzMyNTQmIyIHJzIXMjY3NTQjIgcnND4BMzIWFRQHHgEB3wg6DGgBEmBKFiwdEwecMGRFLgE7FSQ4PyBQQyosEhgSBTdBAUhJMzs3XCk6UTkQVwFADQXKSUn95AEGCwwVH5k8UUsSIyQ2RCZQOzIJPAE3LgNCSSwLMCtSPUEqAygAAQAEAAADggJlAD8A5gCyFgAAK7ARM7I5AQArsgsPEzMzM7QABABDBCuwDTKyAgEAK7QgKhYADSu0IAQAQwQrtBoIFgANK7QaBAArBCu0NC8WAA0rtDQEABMEKwGwQC+wN9a0AwUAGwQrsywDNwgrtB4FABsEK7ADELEWASuwCjK0FQUAJgQrshYVCiuzQBYMCSuwFRCxEgErtBEFABsEK7IREgors0ARDwkrsUEBK7EsNxESsAU5sR4DERKwHDmwFhGxCBo5OQCxGioRErEeLDk5sAgRsxccJDEkFzmwNBKyBQolOTk5sDkRsgM7PDk5OTAxEzIWFRQHHgEzMjc1IzUhFSMRIxEjESMRIgYjIicWFRQjIi4BJzceAzMyNTQmIyIHJzIXMjY3NCciByc0PgHlPFI5F1AjIC1mAddXR4hLAikWHBQHmzyASgI6FiI5QCBQPTIsEBoTBTZCAUdLMTs2WwJlUj1BKgUmEspJSf3kAhz95AEGCwwVH5lfbR4jJjNGJVAxPAk8ATYvQwJJLAowLAAB//b/aQHaAmUAQADZALIMAQArsA8ztA0EAEMEK7AsL7QxBAAOBCuwAC+xGgTpsgAaCiuzQAADCSuwEi+xCQTpAbBBL7AG1rEUBemyBhQKK7NABgwJK7AUELE+ASu0HQUAGwQrsCIysj4dCiuzQD4uCSuzER0+CCu0CgUAGwQrsAovtBEFABsEK7IRCgors0ARDwkrsUIBK7EUBhESsDE5sAoRtgMYHycsNjskFzmwPhKzABolJiQXObEdERESsCM5ALExLBESsR87OTmwABGwHTmwGhKwFzmwEhGwFDmwCRKwBjkwMSUiBiMiJjU0NjsBNSE1IRUjFSMiFRQWMzc2MzIWFRQHHgEXBy4HJyInNDYzMh4HFzI2NzQmAUMKWQ8uciIYwv7JAeRk6gdIFDU0ESIwjBBkFy0PHRQdCyEGKAKZAywSChQSDhIJEQYRAilOAQ7eFo8zFhxgSUmqBhBNDQ07II8sGFIBPwkVDhkJIAYoA1sfHgMIBw8HFAYWAjgrHxYAAf/2/2kB2gOEAEoBGwCyDAEAK7AeM7QNBABDBCuwHDKwPC+0QQQADgQrsAMvtCYEADcEK7AAINYRsSoE6bAhL7EJBOmwGC+0EwQAHwQrAbBLL7AG1rEjBemyBiMKK7NABgwJK7AjELEQASu0GgUAGwQrsBoQsUgBK7QtBQAbBCuwMjKySC0KK7NASD4JK7MgLUgIK7QKBQAbBCuwCi+0IAUAGwQrsiAKCiuzQCAeCSuxTAErsSMGERKwQTmwEBGxAzw5ObAaErUmKC83OEUkFzmwChGwDjmwSBK0ABMqNTYkFzmwIBGwHDmwLRKyFhUzOTk5ALFBPBESsS9FOTmxAAMRErAtObEhKhESsCM5sAkRsAY5sRgNERKyEBYaOTk5sBMRsBU5MDElIgYjIiY1NDY7ATUhNSEmNTQ2MzIXFSYjIhUUFzMVIxUjIhUUFjMyPgEzMhYVFAceARcHLgcnIic0NjMyHgEXMjY3NCYBQwpZDy5yIhjC/skBNE1NNSgdISM7S2pk6gdIFAEzOQ0iMIwQZBctDx0UHQshBigCmQMsEho1GRspTgEO3haPMxYcYEleWTUzCzsHPE1XSaoGEE0ODDsgjywYUgE/CRUOGQkgBigDWx8eIBsfOCsfFgAAAf/2//oCUAJlACkAnwCyEgAAK7QeBAA3BCuyBAEAK7AHM7QFBABDBCu0JiUSBQ0rtCYEAEMEKwGwKi+wGNa0GQUAGwQrsBkQsSEBK7QPBQAbBCuyDyEKK7NADwcJK7AhELAAINYRtAoFABsEK7IACgors0AABAkrsSsBK7EAGRESswMSJSYkFzmwIRGxCAw5OQCxJR4RErAPObAmEbAMObAEErIKGBk5OTkwMQE0JichNSEVIxYVFAceARUUBiMiLgMnNx4DFzI2NTQmKwEnMzI2AbYgFP50Alp8KzcrMGhLN2lHPhoHPwQqRWQwNjNEMGEfSERFAa0TRRdJSUMyQSgVVTFPWklheUYXJhFjhWQBMic0TEkfAAH/9v/6Ay4CZQA7ANQAshQAACu0IAQANwQrsjABACuwMzO0MQQAQwQrtAANFDENK7AmM7QABAA3BCuwKDIBsDwvsBrWtBsFABsEK7AbELEjASu0EQUAGwQrsCwg1hG0NgUAGwQrsjYsCiuzQDYzCSuyLDYKK7NALDAJK7ARELEKASu0AwUAGwQrsT0BK7EsGxESsxQnKC8kFzmwIxGxNDg5ObA2ErA6ObAREbAPObAKErIFAAY5OTkAsSAUERKxBgU5ObANEbMKAxE6JBc5sAASsDg5sDARsxobLDYkFzkwMQEyFhUUByc+AjU0JiciBxYVFAYjIi4DJzceAxcyNjU0JisBJzMyNjU0JichNSEVIRYVFAcWFzYCezxKbzodISEjGyM8CGtHN2lHPhoHPxErRlksNjNEMGEfSERFIBT+dAM4/qYrNxQaQgFnTzlZgSMnMEcZHCICRxgoSVVJYHpFGCYwXn9QATInNExJHyoTRRdJSUMyQSgIG0wAAf/2//UDowJlADcAswCyBQAAK7AOM7EABOmyHwEAK7AiM7QgBABDBCu0GxUFIA0rsRsE6QGwOC+wD9awHTK0DgUAGwQrsCMysg4PCiuzQA4iCSuyDw4KK7NADx8JK7AOELEIASu0NQUAGwQrsyg1CAgrtC0FABkEK7E5ASuxNSgRErAMObAtEbQABSoLLyQXOQCxAAURErEDETk5sBURQAwCCAwNEBIXGB0kJi8kFzmwGxKxKC05ObAfEbAqOTAxJTI3FwYjIiY1NDY3JwcVIzUFJyUmJyIHJz4BMzIXNSE1IRUhFTY3NCc0MzIWFRQHFyIOAhUUFgLzKSQ2OlBESTcoFpNK/uwsAQViICWSLTKaICyJ/isDrf5yBHsDRhceHjcNJSweLD8rOzpSNzFDCSo/7tSfO5hvA044HESP70lJ5gE0EAxKKSEtH2QIEiQXJR4AAAH/9v+JAosCZQA9APYAsiQAACuyBAAAK7IfAAArshABACuwEzO0EQQAQwQrsCcvtCIEADcEK7QKOyQRDSuwMjO0CgQAQwQrsA4ysjsKCiuzQDs3CSsBsD4vsAfWtAAFABsEK7AAELE3ASu0NgUAGwQrsyk2NwgrtB4FABsEK7A2ELEOASu0FQUAGwQrsg4VCiuzQA4QCSuwFRCxLwErtBgFABsEK7IYLwors0AYEwkrsT8BK7E3ABESsgMECjk5ObApEbAMObEVHhESsxwnLDIkFzmwLxGxIi05ObAYErEkJjk5ALEiJxESsCU5sTsEERKzBxgpLyQXObAKEbEMFTk5MDETFBYXBy4BNTQ2MzIXNjc1ITUhFSMVHgEVFA4DFRQeATMyNxcGIiY1ND4DNTQmIyIGHQEjNTQmIyIGc2gyLUF1WEBRKxhL/lUClaA4OSc3NycqKBA5Hyc6imUnNzcnOCQmNEoyGiwpAQ5AhBBAG6xTRGE3MwRjSUlmDUoyMFE0KycSGiEIHj0pTTslOyoqPiYgKS8iRlUgID4AAAD////2/3sBuwM/ECcFoQFCAAQQBgVrAAD////2/3sBuwNcECcFogHWAAAQBgVrAAAAAf/2/3sBuwJlAB8AZgCyCAEAK7ELFDMztAkEAEMEKwGwIC+wBta0FgUAGwQrsgYWCiuzQAYICSuwFhCxEwErsAMytA0FABsEK7INEwors0ANCwkrsBMQtBkFADEEK7EhASuxExYRErQPABAdHiQXOQAwMQUyNjc0JyURIzUhFSMVFAcnPgE3NSMRBRYVFAcGIycWAREOJwEM/u80AcUvVTwTMQPPAQgdWQMCNwpNFREGD/cBN0lJ0kYeMwMgHcP+6+4oIEAVAT0FAAAAAf/2/3sBuwOEACMAfQCyCAEAK7EPGDMztAkEAEMEK7ANMgGwJC+wBta0GgUAGwQrsgYaCiuzQAYICSuwGhCxFwErsAoytBEFABsEK7IRFwors0ARDwkrsBcQsAMg1hG0HQUAMQQrsSUBK7EaBhESsAs5sBcRtQAMExQhIiQXObERAxESsA05ADAxBTI2NzQnJREjNSEnNxMzFSMVFAcnPgE3NSMRBRYVFAcGIycWAREOJwEM/u80AUntPfsxL1U8EzEDzwEIHVkDAjcKTRURBg/3ATdJ5Dv+4UnSRh4zAyAdw/7r7iggQBUBPQUAAAD//wAEAAADggMzECcFoQMI//gQBgViAAD//wAEAAADggNcECcFogNwAAAQBgViAAAAAQAEAAADggOEAEMA8wCyGgAAK7AVM7I9AQArsgsTFzMzM7QABABDBCuxDREyMrICAQArtCQuGgANK7QkBABDBCu0HggaAA0rtB4EACsEK7Q4MxoADSu0OAQAEwQrAbBEL7A71rQDBQAbBCuzMAM7CCu0IgUAGwQrsAMQsRoBK7AKMrQZBQAmBCuyGhkKK7NAGgwJK7AZELEWASuwDjK0FQUAGwQrshUWCiuzQBUTCSuxRQErsTA7ERKwBTmxIgMRErAgObAaEbIIDx45OTmwGRKwEDkAsR4uERKxIjA5ObAIEbMbICg1JBc5sDgSsgUKKTk5ObA9EbIDP0A5OTkwMRMyFhUUBx4BMzI3NSM1ISc3EzMVIxEjESMRIxEiBiMiJxYVFCMiLgEnNx4DMzI1NCYjIgcnMhcyNjc0JyIHJzQ+AeU8UjkXUCMgLWYBOO09+1RXR4hLAikWHBQHmzyASgI6FiI5QCBQPTIsEBoTBTZCAUdLMTs2WwJlUj1BKgUmEspJ5Dv+4Un95AIc/eQBBgsMFR+ZX20eIyYzRiVQMTwJPAE2L0MCSSwKMCwAAAAAAQAEAAADggOEAEYBAACyHQAAK7AYM7JAAQArsgsWGjMzM7QABABDBCuxDRQyMrICAQArtCcxHQANK7QnBABDBCu0IQgdAA0rtCEEACsEK7Q7Nh0ADSu0OwQAEwQrAbBHL7A+1rQDBQAbBCuzMwM+CCu0JQUAGwQrsAMQsR0BK7AKMrQcBQAmBCuyHRwKK7NAHQwJK7AcELEZASuwDjK0GAUAGwQrshgZCiuzQBgWCSuxSAErsTM+ERKwBTmxJQMRErAjObAdEbMIDxAhJBc5sRkcERKyERITOTk5sBgRsBQ5ALEhMRESsSUzOTmwCBGzHiMrOCQXObA7ErIFCiw5OTmwQBGyA0JDOTk5MDETMhYVFAceATMyNzUjNSElNxcnNxMzFSMRIxEjESMRIgYjIicWFRQjIi4BJzceAzMyNTQmIyIHJzIXMjY3NCciByc0PgHlPFI5F1AjIC1mATj+7R3IVj6LWldHiEsCKRYcFAebPIBKAjoWIjlAIFA9MiwQGhMFNkIBR0sxOzZbAmVSPUEqBSYSyklzPFqnI/7hSf3kAhz95AEGCwwVH5lfbR4jJjNGJVAxPAk8ATYvQwJJLAowLAAB//YAAAL3AmUAMgC5ALIeAAArsgUBACuwCDO0BgQAQwQrtCIAHgYNK7EiBOm0DBgeBg0rsC0zsQwE6bAoMgGwMy+wJda0MAUAGwQrsDAQsR4BK7ADMrQdBQAbBCuwCTKyHR4KK7NAHQgJK7IeHQors0AeBQkrsB0QsRUBK7QPBQAbBCuxNAErsR4wERKyIigqOTk5sRUdERKyDBESOTk5ALEiHhESsBE5sAARsRIfOTmwGBK1AwoPHCUrJBc5sAwRsCo5MDE3MjY3ESE1IRUhFTYzMhYVFAcnPgE3NCYjIg4BBxUjNQ4BIyImNTQ2MzIXFSYjIgYHFBbYJUgW/psDAf6tOkhCU3lGH1QDLiMYNxsTSRFKKkFsVkojMS8nIy8CPrQoIAEgSUmyUFJCWIowEW0xISwvKB/6nhIkYERAcAtMDTQpNC0AAv/2AAADFgJlABkAPgDUALIZAAArshMBACuxFiozM7QUBABDBCuxAxkQIMAvtDYEAEMEK7Q8JxkUDSuxPATptA8wGRQNK7QPBABDBCu0HyQZFA0rtB8EAEMEKwGwPy+wEda0LAUAGwQrshEsCiuzQBETCSuwLBCxGgErtCYFABsEK7AmELEZASuxKTkyMrQYBQAbBCuyGBkKK7NAGBYJK7FAASuxJhoRErEDNjk5sBkRsh8hPDk5OQCxPDYRErEAOTk5sCcRsDo5sA8SsRopOTmwJBGwIjmwHxKyCwwhOTk5MDElDgEjIi4ELwE3FxYzMjc1IzUhFSMRIwE0PgIzMhcVJiMiFDMyNzUhFRQOASMnHgMzMjY3NQYjIiYCeyKVOzllRTkiGAUEPA4LMicD5QMgUkn+/iM0KQ8dHhMiTExFKP6qMC8SEggkOFczKIo5NEQ6UHEdNylBTk5BFBUkLiItjklJ/eQBUCY4GgwMRwp0N86bJjMQAhs6OiU6KDMuRAAAAAH/9gAAAhQCZQAUAHAAshIAACuyDAEAK7EPEzMztA0EAEMEK7IMDQors0AMBAkrAbAVL7AK1rQABQAbBCuwABC0BwUADAQrsAcvsgcACiuzQAcMCSuwABCxEgErtBEFABsEK7IREgors0ARDwkrsRYBK7EAChESsAQ5ADAxExQOASMiJjU0NzM1IzUhFSMRIxEj1QMODSdmKDuXAh5RSKYBCRIUD3MdFwOeSUn95AIcAAAAAAL/9gAAAlgCZQAWACgArQCyDAAAK7IGAQArsQkgMzO0BwQAQwQrtA8dDAcNK7EPBOm0JhcMBw0rsSYE6QGwKS+wA9a0IwUAGwQrsgMjCiuzQAMGCSuwAxCwFCDWEbQaBQAbBCuwIxCxDAErsB8ytAsFABsEK7ILDAors0ALCQkrsSoBK7EUAxESsAU5sRojERKwADmwDBGzDyEnKCQXOQCxHQ8RErANObAXEbAfObAmErAAObAGEbADOTAxEy4BNTQ3IzUhFSMRIzUGIyIuAj0BNDciBhUUFjMyNxEhBgcUFjsBF4UiNhhPAmJTSW9XEDI9KqMoMi4qV3f+5ioDSR9NKgFeBkkwJRpJSf3ktEcNGzkmAzcNLRgaJFABFCcoFy9MAAAC//b/+gKyAmUAAwAzAMMAsh4AACu0KgQANwQrsgoBACuwDTO0CwQAQwQrtC4XHgsNK7EuBOmwLhCwMSDWEbQTBABDBCu0BxAeCw0rsQcE6QGwNC+wLNa0GQUAGwQrsw8ZLAgrtAgFABsEK7AIL7QPBQAbBCuyDwgKK7NADw0JK7IIDwors0AIBAkrs0AICgkrsTUBK7EsCBESsRYuOTmxGQ8RErEDFzk5ALExKhESsRksOTmxFxMRErECJDk5sBARsgMBJTk5ObAHErEEADk5MDEBFwcnJTQ2OwE1ITUhFSMVIx4BMzI+ATIWFRQOAiMiLgM1Nx4DMzI1NCMiBgciJgJbSkpK/qwxE8H+NAK8qPsUNhoDLT8uLCI5PSI0bFJCJDMVNFBfLXEfDEgUNnkBn0pKSiQiIWBJSaoxPQwNSSA0TCgSNk1RNwUuIkZYN3AiFgKFAAAAAAH/9gAAAnYCZQAeAJoAsgsAACuyBQEAK7AIM7QGBABDBCu0DwALBg0rsQ8E6bQWFQsGDSuwGDOxFgTpAbAfL7AS1rQcBQAbBCuyHBIKK7NAHBgJK7ISHAors0ASFQkrsBwQsQsBK7ADMrQKBQAbBCuyCgsKK7NACggJK7ILCgors0ALBQkrsSABK7EcEhESsBQ5sAsRsA85ALEVABESsgMMEjk5OTAxJTI2NzUhNSEVIxEjNQ4BByImNTQ3IzUhFSMOAQcUFgEfOGQh/hoCgFFJFnQ1QE5FqgFpWSY7ASy6YDrISUn95NUfRQJGPEc6SkofUhkZFQAAA//2//gCjgJlABkAIgA4AMEAshUAACu0NwQAQwQrsgYBACuxCSgzM7QHBABDBCsBsDkvsBjWtDUFABsEK7MsNRgIK7QDBQAbBCuwAy+0LAUAGwQrsgMsCiuzQAMGCSuwNRCxJQErtCEFACYEK7AhELEnASu0CwUAGwQrsAsQsRwBK7QQBQAbBCuyEBwKK7NAEAkJK7E6ASuxGAMRErAFObE1LBESsAA5sCURshUvMjk5ObEnIRESsCM5sAsRsRoeOTkAsQY3ERKzEBgaHiQXOTAxEy4BNTQ3IzUhFSMVHgMVFA4CIyImNTQFNjU0IyIGFRQXJjU0NzUhIgYHFBYzMjcXIgYVFBcyjyo4I1oCmIoYFx8NQmRzM1ZgAYsuMB0YAU1W/vEUIwFDIhUmIT9RfFoBKQdeNjwcSUlwCw4dKh9EeE0saU9NTx5hNxsfRXB0S04mdFEYJjMFPEcncwEAAAH/9gAAAskCZQAiAKQAsg8AACuyCQEAK7AMM7QKBABDBCu0FiEPCg0rsRYE6bQGEQ8KDSu0BgQANwQrAbAjL7Ac1rQdBQARBCuwHRCxAAErtBMFABsEK7IAEwors0AABQkrs0AACQkrsBMQsQ8BK7AHMrQOBQAbBCuyDg8KK7NADgwJK7EkASuxAB0RErAWObATEbAROQCxESERErEAEzk5sAYRsQQcOTmwCRKwHTkwMSU0LgInNSE1ITUhFSMRIxEjFhUUBgciLgMnNx4CMzIBdhcVKAIBDv3IAtNRSpIjVDktUjkwGQc7Bj5iLT78FTQfNAMMdUlJ/eQBXyk5UEMCMkhaQxwqLX9nAAAC//b/aQK+AmUANABHAQoAshIAACuwJiDWEbQrBAAOBCuyDAEAK7EPNjMztA0EAEMEK7QDPhINDSu0AwQANwQrsAMQsBUg1hG0RgQAHwQrsAMQsAAg1hGxQgTptAk5Eg0NK7EJBOkBsEgvsAbWsTsF6bIGOwors0AGDAkrsDsQsQoBK7Q4BQAbBCuzMjgKCCu0FwUAGwQrsBwysDgQsRIBK7A1MrQRBQAbBCuyERIKK7NAEQ8JK7FJASuxOwYRErArObAKEbUDGSEmL0AkFzmwMhKzAB8gQiQXObEXOBESsR1EOTmwEhGwRjkAsSsmERKxGS85ObEDFRESsRMXOTmxPkYRErE1RDk5sTlCERKwOzmwCRGwBjkwMSUiBiMiJjU0NjsBNSE1IRUjESM1BiMiJxQHHgEXBy4HJyInNDYzMh4BFzI2NzQmNxEjFSMiFRQWMz4CMzIXFjMyAUMKWQ8uciIYwv7JAshSSS0ZHRSLEVQmLQ8dFB0LIQYoApkDLBIVNB8bKU4BDs6t6gdIFAk2LwwnGCoWJ94WjzMWHGBJSf3kvAUFfC0aRgs/CRUOGQkgBigDWx8eIB0dOCsfFi4BEKoGEE0CDgooCgAAAf/2AAACsgJlACcAhwCyEAAAK7IKAQArsA0ztAsEAEMEK7QbIBALDSuxGwTptBMGEAsNK7ETBOm0AiUQCw0rsQIE6QGwKC+wENawCDK0DwUAGwQrsg8QCiuzQA8NCSuyEA8KK7NAEAoJK7EpASsAsRMgERKwHTmwBhGzERUeIiQXObAlErIECCc5OTmwAhGwADkwMRM2MzIXFjMyNzUhNSEVIxEjNQYjIicOBAciJzcWMzI1NCYjIgdwOECJKRscJx794AK8U0kaFBkzAggaJUQqVXIwSU5wSx8rIQGWJpcNFe9JSf3k1ggVDiEvJBwBVjpGdjk1EwAB//b/+gJCAmUAHAB0ALIaAAArtBUEADcEK7IGAQArsAkztAcEAEMEK7QDDBoHDSuxAwTpAbAdL7AA1rQPBQAmBCuyAA8KK7NAAAYJK7APELEEASu0CwUAGwQrsgsECiuzQAsJCSuxHgErsQQPERKxFRo5OQCxDBURErEXGDk5MDE3NDY7ATUhNSEVIxUjIgYVFB4DMzI3FwYjIiZBZzaX/oECTITUKTUeKzYoEF8zRFZ7bJryTW1wSUm6TCgpQSQXB1YqdI4AAAH/9gAGAh0CZQAkAI8AshoBACuwHTO0GwQAQwQrsBEvsQYE6bAgL7QXBABDBCsBsCUvsBTWtAAFABsEK7IUAAors0AUGgkrsAAQsQkBK7QOBQAbBCuzHw4JCCu0GAUAGwQrsBgvtB8FABsEK7IfGAors0AfHQkrsSYBK7EYABESsQYROTmwHxGxCww5OQCxIAYRErIMDhQ5OTkwMTcUHgMzMjY1NCc3FhUUBiMiJjU0NjsBNSE1IRUjFSMiDgJzHCgxJw5FQzk2THpYaolgSI7+lwIndt4XJBIJ8iU7IxcIMTk3JzEqaVBgm1VEZX1JScYYIx4AAAAAAf/2//oCbQJlAC8AuQCyGgAAK7QmBAA3BCuyBgEAK7AJM7QHBABDBCu0KhMaBw0rsSoE6bAqELAtINYRtA8EAEMEK7QDDBoHDSuxAwTpAbAwL7Ao1rQVBQAbBCuzCxUoCCu0BAUAGwQrsAQvtAsFABsEK7ILBAors0ALCQkrsgQLCiuzQAQACSuzQAQGCSuxMQErsSgEERKxEio5ObEVCxESsBM5ALEtJhESsRUoOTmxEw8RErAgObAMEbAhObADErAAOTAxEzQ2OwE1ITUhFSMVIx4BMzI+ATIWFRQOAiMiLgM1Nx4DMzI1NCMiBgciJr0xE8H+NAJ3Y/sUNhoDLT8uLCI5PSI0bFJCJDMVNFBfLXEfDEgUNnkBeSIhYElJqjE9DA1JIDRMKBI2TVE3BS4iRlg3cCIWAoUAAAL/9v/6AiQCZQAlAC4AqwCyIwAAK7IIAQArsAsztAkEAEMEK7QrGSMJDSuxKwTptAUOIwkNK7EFBOkBsC8vsADWtBEFABsEK7IAEQors0AACAkrsBEQsRYBK7QtBQAbBCuwLRCxBgErtA0FABsEK7INBgors0ANCwkrsA0QsSkLK7QeBQAbBCuxMAErsS0WERKxFCM5ObENBhESshkmKzk5OQCxKyMRErMWHhQmJBc5sBkRsREAOTkwMTc0PgI7ATUhNSEVIxUjIgYVFBYXJjU0NjMyHgIVFA4CIyImBT4BNTQjIhUUMQ8fQSuY/pMCLnfYKTJZTRo+NCM1GgwjOjwfaKUBPhYoMi78FTdALGhJSbI+Lj9pFCctNEIeLCYNKj0gDpRMBSkXOzMxAAL/9gAAAmoCZQAQABgAcwCyAwAAK7IOAQArsgAEFTMzM7QPBABDBCu0CREDDw0rsQkE6QGwGS+wDNa0FwUAGwQrsgwXCiuzQAwOCSuwFxCxFAErtAYFABsEK7AGELEDASu0AgUAGwQrsgIDCiuzQAIACSuxGgErsRQXERKwCTkAMDEBIxEjESMVFAYjIiY9ASM1IQEyNj0BIxUUAmpRSoBNQ0BVNAJ0/lEeLZMCHP3kAhzBP1lWPcZJ/qgpMbW5VgAAAAAB//b//wI+AmUAHgBzALINAAArsBUzsgcBACuwCjO0CAQAQwQrtAQPFQgNK7EEBOkBsB8vsADWtBEFABsEK7IAEQors0AABwkrsBEQsQ0BK7AFMrQMBQAbBCuyDA0KK7NADAoJK7EgASuxDRERErEUFTk5ALEPDRESsQAUOTkwMRM0PgEzITUhNSEVIxEjESMiBxQWFwcnLgcqEDEnARL+UgJIUUnwPwKFJTQNDBIhGiEYFQsBOB00K2hJSf3kAWo7PqEbNgsLESEgKSwvNAAAAQAqAAACngJlADEAtACyCgAAK7IEAQArsQcdMzO0BQQAQwQrsCsysicBACu0EwAKBQ0rsRME6bQhJAoFDSu0IQQAKwQrAbAyL7Am1rQfBQAbBCuwHxCxGgErtC4FABsEK7AuELEKASuwAjK0CQUAGwQrsgkKCiuzQAkHCSuyCgkKK7NACgQJK7EzASuxGh8RErQYIyQrMCQXObAuEbEAEzk5ALEkABEStAILFhgwJBc5sCERsRouOTmwBBKwJjkwMSUyNzUjNSEVIxEjNQ4GByImJxYzMjU0JiciFRQzMjcVIjU0PgIzMhYVFAcWATByYWgBA1JJAx4PIBsmKhdloAIoMaM1LkI7BgqVIjMrD0pfxy28h9lJSf3k0wMZCxcNDwcBmz0Meyk2Ay4wAkNzIDAZC2VFoBtBAAAAAAH/9v/ZAf4CZQAkAKwAsgYBACuwCTO0BwQAQwQrsB8vtBEEAEMEK7IfEQors0AfHQkrshEfCiuzQBEVCSuwDC+xAwTpAbAlL7AA1rQPBQAbBCuyAA8KK7NAAAYJK7APELEEASu0CwUAGwQrsgsECiuzQAsJCSuwCxCzEAsYDiu0EwUAEAQrsBMvtBgFABAEK7EmASuxBBMRErAfObALEbIVGh05OTkAsREfERKwGjmwDBGxABg5OTAxEzQ2OwE1ITUhFSMVIyIGFRQzNCc0MzIWFRQHFhcjJiciLgMqRTS//pQCCFLwISjLAUYVJiwkOmIhGUluPycNASY/V2BJSaorIYQaA0MmHTEdT0k4SBwpOTMAAAEAKQAAAlsCZQAvAM8AsgsAACuyJAEAK7EECDMztBwEAEMEK7AGMrIkHAors0AkIQkrtA4ACyQNK7EOBOm0KywLJA0rtCsEACsEKwGwMC+wGda0JgUAGwQrsxQmGQgrtC4FABsEK7AmELEhASu0IAUAGwQrsCAQsQsBK7ADMrQKBQAbBCuyCgsKK7NACggJK7ILCgors0ALBQkrsTEBK7EuJhESsBY5sCERsRwpOTmwIBKxAA45ObALEbErLDk5ALEsABESsgMMFDk5ObArEbEWKTk5sCQSsBk5MDElMjY3NSM1MxUjESM1BiMiLgM1NDcuATU0NjMyFh0BIzU0JyIHFBYXNjMXIhUUAQYbZTlg/FJKX3IkOiAVBzctNUczLkNJKDEBOhUxUiDGsDg5+0lJ/eTFXxYgJhwKOyogVSswSEcoHx8lATAiUgwQRVM0AAH/9gAAAkICZQATAGIAsgwAACuyBgEAK7AJM7QHBABDBCu0Aw4MBw0rtAMEADcEK7IOAwors0AOEgkrAbAUL7AM1rAEMrQLBQAbBCuyCwwKK7NACwkJK7IMCwors0AMBgkrs0AMAQkrsRUBKwAwMRI0NjMhNSE1IRUjESMRIxUUBiMiKh0WAUr+TwJMUUrgChcQAUIoJY1JSf3kAUdYGAwAAAD////2/8sCQgJlECcFmAJYADYQBgWEAAAAAv/2AAAB6QJlAA0AFQBuALILAAArsgUBACuxCBEzM7QGBABDBCu0AA4LBg0rsQAE6QGwFi+wA9a0EwUAGwQrsgMTCiuzQAMFCSuwExCxCwErsBAytAoFABsEK7IKCwors0AKCAkrsRcBK7ELExESsAA5ALEOABESsAw5MDE3IiY9ASM1IRUjESM1BicyNzUjFRQW301oNAHzU0gqSTw32zumWEDeSUn95M0nSjf12iUtAAAAAv/2AAAC5wJlAB8AJwCyALIdAAArsgUBACuxCCYzM7QGBABDBCu0ACMdBg0rsQAE6bQMGB0GDSu0DAQANwQrAbAoL7AD1rQgBQAbBCuyAyAKK7NAAwUJK7AgELEdASuwJTK0HAUAGwQrsAkyshwdCiuzQBwICSuwHBCxFQErtA8FACYEK7EpASuxHSARErAAObEVHBESsgwREjk5OQCxAB0RErEREjk5sCMRsB45sBgSsw8VGyUkFzmwDBGwCjkwMTciJj0BIzUhFSEVNjMyFhUUByc+ATU0JiMiBgcRIzUGJxQWMzI3NSPfTWg0AvH+r0QxRV57RSJTORYUNTVIMqk7LTs426ZYQN5JSbo/V0RWgzARajIpJiYx/v7JI5wlLTD8AAL/9gAAAfYCZQAcACQAkQCyCgAAK7IEAQArsAcztAUEAEMEK7QNIAoFDSuxDQTptBUaCgUNK7QVBABDBCsBsCUvsBLWtB0FABsEK7AdELEKASuwAjK0CQUAGwQrsgkKCiuzQAkHCSuyCgkKK7NACgQJK7EmASuxCh0RErMNFRwiJBc5ALEgDRESsAs5sBoRtAISGAAjJBc5sBUSsBc5MDElNjcRITUhFSMRIzUGByIuAjU0NjMyHwEmJyIPARQWMzI3JwYBTQoE/psCAFJJQT01TCMPWUYoLBQ4KxoaJzcuIySlB/AFBwEgSUn95KYvAik8MBFFaAxQEgEQTiw2EnYOAAAAAQAGAAACTAJlACYAsQCyDQAAK7IHAQArsQodMzO0CAQAQwQrsAAytA8EDQgNK7AYM7EPBOmyDwQKK7NADxIJKwGwJy+wJNa0HwUAGwQrsB8QsRkBK7QEBQAbBCuwDzKyGQQKK7NAGRUJK7AEELENASuwBTK0DAUAGwQrsgwNCiuzQAwKCSuyDQwKK7NADQcJK7EoASuxHyQRErAiObAZEbEAITk5sAQSsBI5ALEEDxESsBU5sAcRsSEkOTkwMRMyFh0BMzUjNSEVIxEjESMVFCMiJjU0NjsBNTQmIyIVFBcjJjU0NoEuSbloAQNSSbkgFmIbCykbEjQSTgxGAmMvN7DPSUn95AEDYwxyGA4hmhwYLw0hHRswPQAAAAAC//YAAAIQAmUAFAAYAIUAsgwAACuyBgEAK7EJFjMztAcEAEMEK7QOGAwHDSuwAzOxDgTpsg4YCiuzQA4SCSsBsBkvsATWtBgFABsEK7AOMrIEGAors0AEAAkrs0AEBgkrsBgQsQwBK7AVMrQLBQAbBCuyCwwKK7NACwkJK7EaASuxGAQRErASOQCxGA4RErAAOTAxEzQ2OwE1IzUhFSMRIxEjFRQGIyImJTUjFQ4bDCloAhpSSc8KFRhhAWfPAR4NIs9JSf3kAQNOEw5wSc/PAAAAAAL/9gAAAjYCZQATAB4AgQCyCQAAK7IDAQArsQYXMzO0BAQAQwQrtAwUCQQNK7QMBABDBCsBsB8vsADWtBoFABsEK7IAGgors0AAAwkrsBoQsQkBK7AWMrQIBQAbBCuyCAkKK7NACAYJK7EgASuxGgARErAYObAJEbEMFDk5ALEUDBESsAo5sAMRsQ8ROTkwMRM0JyM1IRUjESM1BiMiJicWMzI2FzI3NSMWFRQGBxa8OY0CQFJKPVFgfwMNJSk1TFBEvylBNRsBvzQpSUn95NI1eGQKLLVR5SwzMFoBTAAAAf/2//MBvQJlAB8AbgCyCQAAK7IbAQArsB4ztBwEAEMEK7QXAwkcDSu0FwQAQwQrAbAgL7AZ1rQABQAbBCuyABkKK7NAAB4JK7IZAAors0AZGwkrsSEBK7EAGRESsAk5ALEDCRESsQgPOTmwFxGwETmwGxKxExQ5OTAxARQGIyInHgEXBy4IJzcXFjMyPQEhNSEVIwFkSzYJFDp5EDMTICMWJxMxFEAPOx8dSj7+2wHHWQGMM0ICVJMJNhMiKRo0GUUeXRUpLSkujklJAAAA////9v+wAb0CZRAnBZgBmwAbEAYFjAAAAAH/9v/1ApoCZQAnAIYAshwAACuwCDOyFgEAK7AZM7QXBABDBCu0ECUIFw0rsB0ztBAEADcEK7AUMgGwKC+wDda0AAUAGwQrsAAQsRwBK7AUMrQbBQAbBCuyGxwKK7NAGxkJK7IcGwors0AcFgkrsSkBK7EcABESsgcIEDk5OQCxJRwRErIHDSA5OTmwEBGwEjkwMTcUHgQXBy4DNTQ2MzIXNjc1ITUhFSMRIxEOAQcnNjcmJyIGcxkfNx83AiUdQVY3Y0xZQ0JI/fcCpFFKL2ILQggeMS4vRvgcNCMlEBoBQAokQGI4RF9HQgV8SUn95AFYBXIqISofLgksAAP/9gA6Ap8CZQAdAC8AOwCmALIFAQArsAgztAYEAEMEK7AWL7ASM7Q3BABDBCuwITKwMy+wKDOxHATpsAMyAbA8L7AZ1rQ1BQAbBCuwNRCxAwErtAoFABsEK7IDCgors0ADBQkrsAoQsSQBK7QPBQAbBCuyDyQKK7NADwgJK7E9ASuxAzURErUUFhweLjAkFzmwChGyEiEnOTk5ALE3FhESsBE5sDMRswAZFCckFzmwHBKwCjkwMQE+ATc1ITUhFSMVHgMXFAYHIicGIyImNTQ2MzIXFBYzMjY1NCYjIg4FDwEuASMiFRQzMj4CAVAMPiX+NwKplh8sFQgBUkteJyhgSFNcRFdSOi0iKygoDxoREAkJAwNLBjMpVlYaJxUKAWAYNAVrSUluCjE7LBFVZgJZXWdWUWi4J05LMCs8CAwTEBcMCQgqQW11HC0gAAAA////9v+TAp8CZRAnBZgC8//+EAYFjwAAAAH/9gAAAfYCZQAdAI4AshIAACuyDAEAK7APM7QNBABDBCu0FQgSDQ0rsRUE6bQbAhINDSu0GwQAQwQrAbAeL7AY1rQFBQAbBCuwBRCxEgErsAoytBEFABsEK7IREgors0ARDwkrshIRCiuzQBIMCSuxHwErsRIFERKyABUbOTk5ALEIFRESsBM5sAIRsgAKGDk5ObAbErAdOTAxASYnIgYVFBYzMjcRITUhFSMRIzUGIyImNTQ2MzIXARswMi0tQChCPP6xAgBoSUFCR2ZXSCwoAWwSATknNCw8ASFJSf3kpjRqP0VoDAAC//b/8AKQAmUACwAqAK0AsikAACuwEzOyIwEAK7ICDCYzMzO0JAQAQwQrtAgdEyQNK7QIBABDBCsBsCsvsCDWtAUFACYEK7IgBQors0AgIwkrsAUQsRsBK7QOBQAmBCuwDhCxKQErtCgFABsEK7IoKQors0AoJgkrsSwBK7EFIBESshUWIjk5ObAbEbIAER05OTmwDhKyDBITOTk5ALEdKREStBIUERYVJBc5sAgRsQ4bOTmwIxKwIDkwMQEmJyIGFRQWMzI+ATcWFRQGIxcHJTcXMj4CNwYjIiY1NDcjNQUVIxEjEQE3F0UcJygfECwZKyt5ULQy/uUuLxQ2QCwBMjgwVRVsAppXRwHOTQEqFhkhFxJROEVWiZw0+DUoDRw9KCo6ODUcSQJH/eQCHAAAA//2AAAB6QJlAA0AEAAXAHoAsgsAACuyBQEAK7EIDzMztAYEAEMEK7QAFAsGDSuxAATpAbAYL7AD1rQRBQAbBCuyAxEKK7NAAwUJK7ARELELASuwDjK0CgUAGwQrsgoLCiuzQAoICSuxGQErsQsRERKyABAWOTk5ALEUABESsAw5sAURsQ4XOTkwMTciJj0BIzUhFSMRIzUGNzUjBxQWMzI3J99NaDQB81NIKirHFDouRR3KmlhB6UlJ/eTBJ6/T5SYsKdYAAAAC//b/8wKlAmUAIwApAKUAsgMAACuwDzOyIQEAK7EAJTMztCIEAEMEK7QpBQ8iDSu0KQQANwQrsB0ysCkQtAgEAEMEKwGwKi+wH9a0JwUAGwQrsh8nCiuzQB8hCSuwJxCxAwErsCQytAIFACYEK7ICAwors0ACAAkrsSsBK7EnHxESsg8GKTk5ObADEbEFDjk5ALEIAxESsg4UFTk5ObAFEbAXObApErAGObAhEbEZGjk5MDEBIxEjESMnBiMiJx4CFwcuCCc3FxYzMj0BITUhBzUjFRQHAqVRS6QbJkQQCjNgLAQzEyAjFicTMRRADzsfHUo+/tsCr5ylBQIc/eQBHiUsAkl2LwI2EyIpGjQZRR5dFSktKS6OSf+2kA8XAAAB//b/ugHwAmUANADIALIFAAArtAYEAB8EK7IWAQArsBkztBcEAEMEK7QyIwYXDSuxMgTptBMcBhcNK7ETBOkBsDUvsAzWtAAFABsEK7AeMrAAELQQBQAxBCuwEC+yEAAKK7NAEBYJK7AAELEUASu0GwUAGwQrshsUCiuzQBsZCSuzLxsUCCu0KAUAGwQrsTYBK7EADBESsA45sBQRsiMtMjk5ObAvErAGObAbEbEFLDk5ALEyBRESsgwoLDk5ObAjEbEOITk5sBwSsB45sBMRsBA5MDE3FB4CFwciLgM1NDcmNTQ2OwE1ITUhFSMVISIVFBYXNjMyHgIVFA4BByc2NzQmIyIGezJRUyoRDj1fUjtBSyMZ7v6jAfpV/ucIJBYvKyE5OSEWEhM7LAE9MDlYex4xHxMEPAodKkktOThLPhsmYElJqgcNNxIQCxs4JxUqExEuFyEYIDoAAAAB/4cCZv/LAyAAAwAjALACL7QDBAALBCsBsAQvsALWtAEFABsEK7QBBQAbBCsAMDEDFSM1NUQDILq6AP////YAAADsAyAQJwWWAMgAABAGBZoAAAAB/oD/lf8UACkAAwAcALACL7QABAAOBCsBsAQvsAPWtAEFAA4EKwAwMSUXByf+ykpKSilKSkoAAAEAF//xAbgCSwAiAGUAsgkAACu0EAQANwQrsCAvtB0EADcEKwGwIy+wGta0AAUAGwQrsgAaCiuzQAAfCSuwABCxFAErtAYFABsEK7EkASuxABoRErAOObAUEbMDCRAXJBc5ALEgEBESswMNDhokFzkwMRMUHgMXFAYjIi4BJzcWMzI+ATU0LgM1NDY7ARUjIgaFP1paPwFjSjd2QwQzWWEWLik/W1s/PjPm6Q0YAd8QPEZMVSNAWDg3CzNmDCMbGEVHSU0eMUBHFQAAAAH/9gAAAOwCZQAHAEAAsgMAACuyBQEAK7AAM7QGBABDBCsBsAgvsAPWtAIFABsEK7ICAwors0ACAAkrsgMCCiuzQAMFCSuxCQErADAxEyMRIxEjNTPsV0hX9gIc/eQCHEkAAAAB//YAAAKIA2UAGgB1ALIQAAArshIBACuwDTO0EwQAQwQrsAsysAcvtBkEAEMEK7IHGQors0AHAAkrAbAbL7AQ1rAUMrQPBQAbBCuwCzKyDxAKK7NADw0JK7AQELAWINYRtAkFABsEK7IWCQors0AWEgkrsRwBKwCxBxMRErAWOTAxASMuBCMiFRQXMxUjESMRIzUzJjU0NjMyAohUBhZFSWszaw5dV0hXVRFuVbwCZQcZPzAobhgxSf3kAhxJNhhOZAAAAf8NAAEA7ANXAB8AjQCyDAEAK7AHM7QNBABDBCuwBTKyDA0KK7NADAoJK7ATL7QABAA3BCsBsCAvsB3WtBgFABsEK7AYELEKASuxDhAyMrQJBQAbBCuwAzKyCQoKK7NACQcJK7IKCQors0AKDAkrsSEBK7EYHRESsBs5sAoRsgATGjk5OQCxDQwRErEaGzk5sBMRsQMdOTkwMQMyFhUUBzMVIxEjESM1MzY1NCYjIg4CBxQXIyY1NDY/XXgBV1dIV1kDUj0NICYaAS9OKWUDV3NfGQdJ/eUCG0kVCj5OBg0eFCs7NDcwVwAAAAAB/kH+9gAN//IAGgBdALIFAAArtAAEAB8EK7ALL7QVBAAfBCuyFQsKK7NAFREJKwGwGy+wEda0EgUAGwQrsBIQsRgBK7QIBQAbBCuxGBIRErIFCwM5OTkAsQAVERKxAgg5ObAFEbADOTAxByIHJzYzMhYVFAYjIi4DJzMeATMyNjU0JnE1Myg7VUc3a1InQUUzJwhHDXZHOj4gSy0wOkkuQEUKGy5NM01IJSIaIAAA///+w/72AI//8hAPBZ3+0P7owAAAAf7Q/vT/8v/yABkAOACyEQAAK7QUBAAfBCuwCS+0AAQAKwQrAbAaL7AO1rQXBQAbBCsAsQAJERKwBzmwFBGxBg45OTAxBzI+AzcXBiMiLgI1NDY7ARUjIgYVFBaJDhgUCxEDIi5FHDY5JEU5YVQfJDnJBAgFCwIzLgoZNSU4ST0kHB0hAAAAAAH+0P7UACEAegAoAHEAsCEvtBgEACsEK7ASL7QNBAArBCuwBi+0AwQAKwQrAbApL7Al1rQWBQAbBCuzCBYlCCu0AAUAGwQrsAAvtAgFABsEK7EIJRESsCc5ALEYIRESsB85sBIRsR4lOTmwDRKyCxAnOTk5sAYRsQgPOTkwMSU0NjsBFSMiFRQWFzYzNjcXBiMiDgEVFDMyPgI/ARcGIyIuATU0Nyb+0EQ6YVRDLiEIIhgnJilEFhoWXg4VFgYNDScpTytIPBtDAzdAQjEaJAQBBBg3KgUYFzcCCQIICDYpETguMCMhAAAB/tQCkABKAzsADwBAALAHL7QABAA3BCuyAAcKK7NAAAQJK7AKMgGwEC+wCta0CwUAGwQrsAsQsQMBK7QEBQAbBCuxAwsRErAHOQAwMQMyNjczFAYjIiYnMxQeAnErRgFJb0tMbwFHHSohAtgtNk5dX0wdKxMIAAAB/j0CZv+vA1wAFwBQALIFAwArtBQEAB8EK7IUBQors0AUDQkrsBQQsBEg1hG0CAQAKwQrAbAYL7AL1rQOBQAbBCuwDhCxAQErtAAFABsEK7EBDhESsQgUOTkAMDEDIzU0JiMiBiMiJj0BMxUUFjMyNjMyFhVRPyMZCnAdJDxCERYXXxk1RQJmNB0iIS4pTTUXFRo5HwAAAAH+fAJl/7QDhAADABwAsAEvtAMEAAcEKwGwBC+wAta0AAUABwQrADAxAyMnN0xL7T0CZeQ7AAAAAf5gAmX/uAOEAAYAEgCwAS+0BgQABwQrAbAHLwAwMQMjJTcXJzdIRf7tHchWPgJlczxapyMAAP///7cAAAEtAzsQJwWhAOMAABAGBZoAAP///yEAAADsA1wQJwWiAOQAABAGBZoAAAAB/2AAAADsA4MACwBGALIDAAArsgUBACuwADO0BgQAQwQrsAoyAbAML7AD1rAHMrQCBQAbBCuyAgMKK7NAAgAJK7IDAgors0ADBQkrsQ0BKwAwMRMjESMRIzUzJzcTM+xXSFdX7T37VAIc/eQCHEnjO/7iAAH/QAAAAOwDhAAOAEsAsgMAACuyBQEAK7AAM7QGBABDBCuwDTIBsA8vsAPWtAIFABsEK7ICAwors0ACAAkrsgMCCiuzQAMFCSuxEAErsQIDERKwBzkAMDETIxEjESM1MyU3Fyc3EzPsV0hXXf7tHchWPotUAhz95AIcSXM8Wqcj/uEAAAH/Xv8aADn/5wADACQAsAEvtAMEAAoEKwGwBC+wAta0AAUACgQrALEDARESsAI5MDEXByczOSG6V8YgzQAAAAABAAAAAQCfAmUABQA4ALIBAQArtAQEAEMEK7IBBAors0ABAwkrAbAGL7AD1rQCBQAbBCuyAgMKK7NAAgAJK7EHASsAMDETIxEjETOfV0ifAhz95QJkAAD///7uAAAA7ANcECYFmgAAEAcUV/12AAAAAwAV//oDOAMPAAMAEwBiAScAskAAACu0SQQANwQrsCkg1hG0LgQANwQrsgsBACu0BAQANwQrsgQLCiuzQAQICSuwDjKzFAQLCCu0WAQAQwQrtDkeQAsNK7Q5BAArBCu0UlBACw0rtFIEAB8EK7QjM0ALDSu0IwQANwQrAbBjL7BV1rQXBQAbBCuzTBdVCCu0OwUAGwQrsBcQsQ4BK7QPBQAbBCuwDxCxMQErtCYFABsEK7MIJjEIK7QHBQAbBCuwBy+0CAUAGwQrsWQBK7FMVRESsBk5sQ4XERKwHDmwOxGxHjk5ObEHDxESQAkBAwshIykrLjYkFzkAsS5JERKwKzmwORGyLDtMOTk5sFASszEmRlEkFzmxUh4RErIZNkc5OTmxIzMRErIhF1U5OTmwWBGxXl85OTAxARcHJxcyNjczFAYjIiYnMxQeAgUyFhUUBx4DMzI+AjMyFhUUBiMiJzcWMzI2NTQnIg4DIxYVFA4CIyIuAzU3FjMyNjU0JyYjBycyNjU0JiMiDgIPASc0PgECTkpKSkcrRgFJb0tMbwFHHSoh/rM7UDUWIg8TDBpDN0UcQ1JQQjoqHyAlIStRDyQoMEcoCxwvMx0oUzwyGTl9TykoHiFHGSQwXicfESAdEA4NOCpZAw9KSkpiLTZOXV9MHSsTCCpaQUYmBxAIBjI7Mm9cWXMxRzBAL5YCIC4tIBsYLUAhDjNISzICIdQvIjMcHAhHNC8oKQkUDQwNKAQuMgAAAf+HAmb/ywOEAAMAIwCwAi+0AwQABwQrAbAEL7AC1rQBBQAbBCu0AQUAGwQrADAxAxEjETVEA4T+4gEeAAAAAAH94P7/AAb/MgADABkAsAEvtAIEABMEK7QCBAATBCsBsAQvADAxEyE1IQb92gIm/v8zAAAB/iwC4P8yA4QAEQAvALABL7AGL7QMBAArBCsBsBIvsAjWtAAFAAgEKwCxBgERErEACDk5sAwRsAo5MDEDBy4DIyIHNjc2MzIeA84yCB0TKBsxKBchFRIhMCESGwLlBQorGBUWMSQDESYfOwAB/zIC4AA4A4QAEQAvALARL7AML7QGBAArBCsBsBIvsADWtAoFAAgEKwCxDBERErECCjk5sAYRsAg5MDEDPgQzMhcWFyYjIg4CB84IGxIhMCESFSEXKDEbKBMdCALlDjsfJhEDJDEWFRgrCgAC/tQCagBKA4QAAwATAFIAsgsDACu0BAQANwQrsgQLCiuzQAQICSuwDjKwAy+0AAQANwQrAbAUL7AO1rAAMrQPBQAbBCuwDxCxBwErtAgFABsEK7ABMrEHDxESsAs5ADAxASEVITcyNjczFAYjIiYnMxQeAv7VAXT+jLorRgFJb0tMbwFHHSohArBGty02Tl1fTB0rEwgAAAH+SP9cAAD/2wAJABIAsAEvtAYEADcEKwGwCi8AMDEGICc3HgEyNjcXR/7WRzgXaUhpFzikVikZHh4ZKQAAAP///kj+1AAA/9sQJwWyAAD/eBAGBbIAAP////b/lQL3AmUQJwWYAfEAABAGBXEAAP////b/TAMWAmUQJwWYAqz/txAGBXIAAP////YAAAIUAmUQJwWYAcEAihAGBXMAAP////b/mwLJAmUQJwWYAm0ABhAGBXgAAP////b/TAJtAmUQJwWYAm3/txAGBX0AAP////b/TAIkAmUQJgV+AAAQBwWYAkX/t/////b/0ALnAmUQJgWHAAAQBwWYAf8AO/////b/xAI2AmUQJwWYAkUALxAGBYsAAAAB//b/RAOOAmUARwDvALIoAAArsAoztAUEADcEK7IMAAArsh4AACuyOQEAK7A8M7Q6BABDBCuwGS+0DwQAQwQrtDQuKDoNK7Q0BAA3BCsBsEgvsCjWsDcytCcFABsEK7A9MrInKAors0AnPAkrsignCiuzQCg5CSuwJxCxIQErtAMFABsEK7AdINYRtA0FABsEK7NAAyEIK7RFBQAaBCuxSQErsUAdERKwHzmwAxGwJTmxRQ0RErQFCiRCRyQXOQCxDxkRErAXObAoEbEWHTk5sAUSsggfKjk5ObAuEUAMByElJikrMDE3Pj9HJBc5sDQSsEU5sDkRsEI5MDElIgYHFDMyNxcGIyIGFBYzMj4ENxcGIyIuATU0NyY1NDY3JwcVIzUFJyUmJyIHJz4BMzIWFzUhNSEVIRU3JzQzMhYVFAcDEitNAkw+Bzg4TxMjNygMFg4QBxACJilCJ1BEICs0KReOSP7xKwEBYh4jkSsFxhskbx/+NQOY/nt8AkIYHR7gLSZBLT04GDolAwMIAwsBPCoYQS40JSc9LkQJKT3v1Zs5lWwETTcKU10t50lJ4DUaSiogLRwAAAH/9v7dAqICZQBcASgAshABACuwEzO0EQQAQwQrsD8vtDQEADcEK7ArL7QhBABDBCuwWi+wUTO0CgQAQwQrsA4ysloKCiuzQFpWCSsBsF0vsAfWtAAFABsEK7AAELFWASu0VQUAGwQrsFUQsQ4BK7QVBQAbBCuyDhUKK7NADhAJK7MeFQ4IK7RIBQAbBCuwSC+0HgUAGwQrsB4QsDEg1hG0RAUAGwQrsEQvtDEFABsEK7AVELFOASu0GAUAGwQrshhOCiuzQBgTCSuxXgErsVYAERKyAwQKOTk5sFURsAw5sR4OERKwRjmwMRGwUTmwFRKwHDmwThGwTDmwGBK1ISYrNDc/JBc5ALE0PxESsD05sCsRsDw5sCESsSlGOTmwWhG1BxgEKEhOJBc5sAoSsQwVOTkwMRMUFhcHLgE1NDYzMhc2NzUhNSEVIxUeARUUDgMVFBYzMj4ENxcGIyIOAxUUFjMyPgU3FwYjIi4CJzQ3JjU0PgM1NCYjIgYdASM1NCYjIgZwZzAsP3JWPU8sFkr+XgKGnTQ9IjAwIiwxDBYOEAcQAicqSA8TGQ4LPSIKEQ8KDgYPAicqRRg2PioBIjsiMTAiMyQmNkcsHiIyARU9ghA+GKlTRVw2MQVfSUljDEwzK0YtJysXEy8DAwgDCwE8KgEGChUPIiABBQIIAwoBPSkMGjknOCQlPyQ+LSo3HiEkKCVEUhsiMAAAAAH+YP7UACgAcQA3AKUAsCAvtBsEAB8EK7A1L7AsM7QKBAATBCuwDjKyNQoKK7NANTEJKwGwOC+wB9a0AAUAEQQrsAAQsTEBK7QwBQARBCuwMBCxJQErtBgFABsEK7AYELEqASu0EwUAEQQrsTEAERKyAwQKOTk5sDARsAw5sRglERKwDjmwKhGxFig5ObATErEbIDk5ALEbIBESsB45sDURtAcTBB0lJBc5sAoSsAw5MDEFFBYXBy4BNTQ2MzIXNjMyHgIVFA4CFRQWMzI3FwYjIi4CNTQ+AjU0JyIGHQEjNTQmJyIG/pZKJiAvV0EuPR8XMiw8GgklLiUfIiEiHTAmJzkbDCYvJ0sUJzYlEB0jEC5hDi8Tfz40RSouGCYeDSNCKC4RDiMVLCAXIx8NHzkmMxgzAiIZMz4YFwEnAAAAAf5f/tQAPAEAAE0A0ACwMi+0KQQAEwQrsCEvtBwEAB8EK7BLL7BCM7QKBAATBCuwDzKySwoKK7NAS0cJKwGwTi+wB9a0AAUAEQQrsAAQsUcBK7RGBQARBCuwRhCxOwErtBkFABEEK7A3INYRtCYFABEEK7AZELFAASu0FAUAEQQrsUcAERKyAwQKOTk5sEYRsAw5sRk3ERKxDzk5ObFAJhESsRc+OTmwFBGzHCEpMiQXOQCxKTIRErAwObAhEbAvObAcErEfOTk5sEsRtAcUBB47JBc5sAoSsAw5MDElFBYXBy4BNTQ2MzIXPgEzMh4CFRQOAhUUFjMyNxcGIyIOAhUUFjMyPgM3FwYjIi4CJzQ3JjU0PgI1NCciBh0BIzU0JiciBv6XSiYgMFhBMDwgCTAQEyYyHycvJyQjISIdJTENEBYLKxwKDg8FFAIeIDkQJi4fARksJy4nSxQnNiUQHSN/LmEOLxOCQihKKhIcBxMuIhg/MTQPDSQVLCACBhIOFhwBBwENAS4eCBQrHSobHDAeOyczFjQBIhkzPhgXAScAAAAAAQFz/6ABtgKAAAMAHQABsAQvsALWtAEFABsEK7QBBQAbBCuxBQErADAxAREnEQG2QwI7/WVFApsAAAD//wDu/64CBgKOECYFwFAOEAcFwP97AA4AAgBaAF0B5AHyAAsAFwBJALADL7QMBAA3BCuwEi+xCQTpAbAYL7AG1rQVBQAbBCuwFRCxDwErtAAFABsEK7EZASuxDxURErEJAzk5ALESDBESsQYAOTkwMQEUBiMiJjU0NjMyFgcyNjU0JiMiBhUUFgHkaV1eZmlbXGrGOkNCOzZFQAEnYWlnY2BrbeBHPjpERjw+QwAAAAACAHEAAAG/AmUADQAYAFgAsgUAACuyFgEAK7QABABDBCu0EQgFAA0rtBEEADcEKwGwGS+wC9a0DgUAJgQrsA4QsQUBK7ATMrQEBQAbBCuxGgErsQUOERKxAAg5OQCxEQgRErAGOTAxATIWFREjEQYjIiYnNDYHFBYzMjU0JiMiBgEVTV1JIzlKXANpHjghYT8iJDUCZWdS/lQBOxxZRkleoywvXCcyNgABAFj/vAHyAmUAHgBOALIcAQArtAMEAEMEK7AQL7QUBAAQBCsBsB8vsBnWtAYFABsEK7EgASuxBhkRErAMOQCxFBARErILDhY5OTmwHBGxBh45ObADErAAOTAxEz4BMzIWFRQOAgcXBycGIyInNDcyFz4BNzQmJyIHWBd9L1p9IzcyF388ixISZQRCOy8wUwJOPzVeAiMULnFVNFc3IAnNK94GSjQDLw9xOTdEAi8AAAEAZP9/AeYCZQAsAHwAsgoBACu0EAQAQwQrsCIvtCcEAA8EK7AEL7EFBOkBsC0vsADWtBwFABsEK7MVHAAIK7QIBQAbBCuwCC+0FQUAGwQrsS4BK7EACBESsBc5sBURsCA5ALEnIhESsR8qOTmwBBGwADmwBRKwFzmwChGxDRU5ObAQErAOOTAxJTQmKwEnMzI1NCciBgcnNjMyHgIVFAceAxcUBgcXBycmPQE0MzIWFzI2AZxiNkEsa3BmHU8PLXc3HTY2IUAOHSYYAVc/UDdvczMdQhIvQs0xP0tNRAMXFUIzDR47KFQhBRMiOCFIWAx0MJ8PPgQ8Kh9FAAIATgAEAf4CZQAjACwAeQCwCi+0KQQAQwQrAbAtL7AN1rQnBQAbBCuwFjKzGScNCCu0EgUAGwQrsBIvtBkFABsEK7AnELErASuwIzK0BwUAGwQrsx8HKwgrtAMFABsEK7EuASuxGQ0RErAVObErJxESswoPBRwkFzmwHxGwHjmwBxKwADkAMDEBHgEVFAcWFRQGIyImNTQ3LgE1NDY3Fw4BFRQWFz4BNzQuAScDDgEVFDMyNTQByBgenGtfR0VbZVpELRc/EihkLENKAg4dB1gkOVhdAmUbRBVVaVdJQE9PQ0hXP0wzIEIMJAU9ERNdGCtMGAkaKQz+wRhGFEtLOQABAGYAAAIXAmYAHAB+ALIHAAArsAYzsAovtBYEAEMEKwGwHS+wDda0EwUAGwQrsBMQsRsBK7QDBQAPBCuxHgErsDYausL37MAAFSsKsAcuDrAIwAWxBgf5DrAFwACxBQguLgGzBQYHCC4uLi6wQBoBsRMNERKwDzmwGxGyChAWOTk5sAMSsBg5ADAxATIWFRQHEyMnBiMiJjU0NxcOARUUFjMyNy4BNTQBiiclF1hNTCs3T2c6RBQgRS4tEwgLAeI/GUkq/unwH21cX20iEGYwRz0TDzgPXgABAGb/mAHkAmUAMACdALIsAQArtCcEAEMEK7IqAQArtCkEACsEK7IlAQArsB0vsQwE6bAGL7QDBABDBCuwKi8BsDEvsCDWtAkFABsEK7AkINYRtAAFABsEK7AJELEQASu0FQUAEAQrsTIBK7EQCREStAwdIicsJBc5sBURtgQFFxkaKSokFzkAsQwdERKxFxo5ObAGEbESFTk5sAMSsCI5sCoRsQAkOTkwMRMUFjsBFyMiBhUUFjMyNzQnNDMyFhUUBxcHJyIGIyImJzQ3JjU0NjMyHwEmIyIOArBWJEgYWi9AQDAbDANAHSEnOEM4BiILUmoDVmdfQkghESlHCR0jGAHZH0RJSCkoNwkEGVYoHjEngCODCF9LYDI2WDtNDUUJBg4cAAAAAAIAIgAGAf4CXAAXACMAdACwBi+xEATpshAGCiuzQBANCSuwGy+0AAQANwQrAbAkL7AN1rQOBQAbBCuwDhCxFQErtB0FABsEK7AdELEYASu0BAUAGwQrsSUBK7EODRESsAs5sR0VERKxEAY5ObAYEbEAEjk5ALEbEBESsgQVIjk5OTAxATIeARUQIyIuBDUzEDMyNyImNTQ2FzQmJyIHFB4CFzYBcTVDFec0UjQjEQdEsm8XS2NIfh4pNQMbLB8PCgIzRlQw/p0zXm6RfEr99H1vUkZfyEA/AV0kNRoMAjAAAQCCAAYBygJjABIAQgCwAi+xEATpshACCiuzQBASCSsBsBMvsAfWtA4FABsEK7AOELESASu0AAUAGwQrsRQBK7ESDhESsgoCCzk5OQAwMSUGIyIuAjU0NxMzAwYVFDMyNQHKEpUcNDMeEHtNgg9aXrKsDR06KCotAXr+disbQ2IAAAAAAgCB/4kBygJlABkAJABoALIgAQArtAAEAEMEK7IYAQArsAgvsRoE6QGwJS+wF9a0IgUAGwQrsCIQsR0BK7QFBQAbBCuwEiDWEbQLBQAbBCuxJgErsSIXERKwFTmwEhG2AA0QCBQaICQXOQCxIBoRErEVBTk5MDEBMh4CFRQGBxMWFRQHLgEnNjU0JwMmNTQ2FzI2NTQmIyIVFBYBGTRLIw9mUJoLRgYaAiQI2xFXUicxMideMgJlJTcsD0hfAf74FxlFIAorAxQaCw0BdB0yQlnvMiAlL1kiKwAAAAIAWwC2AS8BiAAKABUAUgCwBi+0EQQAHwQrsAsvtAAEAB8EKwGwFi+wCNa0DgUAGwQrsA4QsRMBK7QDBQAbBCuxFwErsQ4IERKwBjmwExGxBQA5OQCxCxERErEIAzk5MDETMhYVFAYiJjU0NhciBhUUFjI2NTQmxSw+Plg+PysSGhokGhkBiD4sKz0+Kyo/PhoREhoaERMZAAAAAAEAgQLNAQIDRQADAC4AsAEvtAIEABEEK7QCBAARBCsBsAQvsAHWtAAFABAEK7QABQAQBCuxBQErADAxASM1MwECgYECzXgA//8AHgAAAwoDOxAnBaECwAAAEAYFYQAA//8AHgAAAtcDIBAnBZYCqAAAEAYFYQAA//8ABAAAA4IDIBAnBZYDXAAAEAYFYgAA//8ABAAAA4IDXBAmFFcAABAGBWIAAAAA//8AHv9cAtcCZRAnBbICdgAAEAYFYQAA//8AHv7UAtcCZRAnBbMCdgAAEAYFYQAA////9v9mAskCZRAnBZgC4QA3ECcFmAJq/9EQJwWYAfcAOxAGBXgAAAAD//YAAAI2AmUAEwAbACAAiACyCQAAK7IDAQArsQYeMzO0BAQAQwQrtAwZCQQNK7QMBABDBCsBsCEvsADWtBwFABsEK7IAHAors0AAAwkrsBwQsQkBK7AdMrQIBQAbBCuyCAkKK7NACAYJK7EiASuxHAARErEUHzk5sAkRsgwZGzk5OQCxGQwRErAKObADEbMPERQdJBc5MDETNCcjNSEVIxEjNQYjIiYnFjMyNhcOAQcWMzI3Jxc1Ixa8OY0CQFJKPVFgfwMNJSk1PA82IxtdOzNwlr8pAb80KUlJ/eTSNXhkCiwbISwBTCurheUsAAAB//b/7AJCAmUAFwB4ALIOAAArtA8EAEMEK7ALMrIGAQArsAkztAcEAEMEK7QDEg4HDSu0AwQANwQrshIDCiuzQBIWCSsBsBgvsBDWsAQytAsFABsEK7ILEAors0ALCQkrs0ALDQkrshALCiuzQBAGCSuzQBAOCSuzQBABCSuxGQErADAxEjQ2MyE1ITUhFSMRMxUhNSERIxUUBiMiKh0WAUr+TwJMUUf9yAGn4AoXEAFCKCWNSUn+GUlJARJYGAwAAAAAAf/2/+wCyQJlACYAvwCyEQAAK7QSBABDBCuwDjKyCQEAK7AMM7QKBABDBCu0GiURCg0rsRoE6bQGFREKDSu0BgQANwQrAbAnL7Ag1rQhBQARBCuwIRCxAAErtBcFABsEK7IAFwors0AABQkrs0AACQkrsBcQsRMBK7AHMrQOBQAbBCuyDhMKK7NADgwJK7NADhAJK7ITDgors0ATEQkrsSgBK7EAIRESsBo5sBcRsBU5ALEVJRESsQAXOTmwBhGxBCA5ObAJErAhOTAxJTQuAic1ITUhNSEVIxEzFSE1IREjFhUUBgciLgMnNx4CMzIBdhcVKAIBDv3IAtNRR/1BAi6SI1Q5LVI5MBkHOwY+Yi0+/BU0HzQDDHVJSf4ZSUkBKik5UEMCMkhaQxwqLX9nAAEAWAABAfICZQAUAEAAshIBACu0AwQAQwQrAbAVL7AL1rQKBQAbBCuwChCxDwErtAYFABsEK7EWASuxCgsRErADOQCxAxIRErAAOTAxEz4BMzIWFRQGBxUjNTI2NzQmJyIHWBd9L1p9fEFIT2wDTj81XgIjFC5xVWGGDqnie0E3RAIv////9v+1Am0CZRAnBa4CJgC2EAYFfQAAAAL/9v/sAfYCZQAHACgApwCyFAAAK7QVBABDBCuwETKyDAEAK7APM7QNBABDBCu0GQMUDQ0rsRkE6bQhJhQNDSu0IQQAQwQrAbApL7Ae1rQABQAbBCuwABCxFgErsAoytBEFABsEK7IRFgors0ARDwkrs0AREwkrshYRCiuzQBYMCSuzQBYUCSuxKgErsRYAERKzBRkhKCQXOQCxAxkRErAXObAmEbQGCAoeJCQXObAhErAjOTAxExQWMzI3JwYXNjcRITUhFSMRMxUhNSE1BgciLgI1NDYzMh8BJiciB3M3LiMkpQfaCgT+mwIAUkj+FAFbQT01TCMPWUYsKBQ4KxoaASEsNhJ2DkkFBwEgSUn+GUlJcS8CKTwwEUVoDFASARAAAAAC/scCaf/qAx0ADQAZAGYAsAsvtAQEAB8EK7IECwors0AEAAkrsAcysBcvsREE6QGwGi+wANa0AQUAEQQrsAEQsQ4BK7EUBemwFBCxBwErtAgFABEEK7EUDhESsQsEOTmxCAcRErAJOQCxERcRErEOFDk5MDEBMx4BMzI2NzMOASMiJjc0NjMyFhUUBiMiJv7HNgQvKScxAzYFVDo0XGUbEhMYGBMSGwLwIywuIUBHSj0RHBoTFRYYAAAAAAMAFAArAR4CIwALABUAGQBVALAPL7QABAATBCuwBi+0FAQAEwQrAbAaL7AR1rQJBQARBCuwCRCxAwErtAwFABEEK7EbASuxCRERErAYObADEbMODxMUJBc5ALEGABESsQwROTkwMRMyNjU0JiMiBhUUFjcUBiImNTQ2MhYTJzcXhhMZGhITHh1zM1Y6OlI3EeIq4AGQGhcUGxsVFhowKDs4LSo3PP5E4SrfAAAEACIAMQDlAfsACwAVACEAKwB9ALAPL7QABAATBCuwBi+0FAQAEwQrsCUvtBYEABMEK7AcL7QqBAATBCsBsCwvsBHWsCcytAkFABEEK7AfMrAJELEDASuwGTK0DAUAEQQrsCIysS0BK7EDCREStw4PExQkJSkqJBc5ALEGABESsQwROTmxHBYRErEiJzk5MDE3MjY1NCYjIgYVFBY3FAYiJjU0NjIWJzI2NTQmIyIGFRQWNxQGIiY1NDYyFoYTGRoSEx4dczNWOjpSN18TGRoSEx4dczNWOjpSN2QaFxQbGxUWGjAoOzgtKjc8rRoXFBsbFRYaMCg7OC0qNzwAAAAAAQABAAACkAIuACUAtwCyCwAAK7APL7QYBAATBCuwHi+0IwQAEwQrsAUvsAgztAYEABMEKwGwJi+wFNa0FQUAEQQrsBUQsSEBK7QgBQARBCuwIBCxGwErtAAFABEEK7AAELELASuwAzK0CgUAEQQrsgoLCiuzQAoICSuyCwoKK7NACwUJK7EnASuxGyARErIYDyM5OTmwABGwDTkAsQ8LERKwDDmwGBGwAzmwHhK0AgANICEkFzmwIxGwFDmwBRKwFTkwMQEUBxcRITUhFSMRIzUnBiMiLgInNx4BMzI2NTQmIyIHJzYzMhYB2wM+/esCj0czUjRDO2FBKgwzG3tGKDc/KCkPLxRTPF4BMgkSWwE/MzP+BVx+STpiaToQhZc9LSdOPAplawABAAEAAAM9AnsANgDlALIFAAArsDUzsAkvtBIEABMEK7AYL7QdBAATBCuwJS+xAjMzM7QmBAATBCuwMTKyJiUKK7NAJi8JKwGwNy+wDta0DwUAEQQrsA8QsRsBK7QaBQARBCuwGhCxFQErtCAFABEEK7AgELEFASuwIzK0BAUAEQQrsAQQsTYBK7AuMrQ1BQARBCuwMDKyNTYKK7NANTMJK7E4ASuxFRoRErISCR05OTmwIBGwBzmxNgQRErAnOQCxCQURErAGObASEbAjObAYErQHGhsgIiQXObAdEbEOADk5sCUSsQ8uOTmwJhGwLDkwMQEmJyMRIzUnBiMiLgInNx4BMzI2NTQmIyIHJzYzMhYVFAcXESE1IR4BHwEeARc1MxUzFSMRIwLAFjQtM1I0QzthQSoMMxt7Rig3PygpDy8UUzxeAz796wKFAgoCDQITCjNKSjMBsToQ/gVcfkk6Ymk6EIWXPS0nTjwKZWs5CRJbAT8zAgYBCwIUDoVNM/4FAAAAAv/y/84B+wMWACAAPgDMALAyL7Q6BAATBCuwBS+0BgQAEwQrsAIysA0vtB4EABMEK7AQINYRtBsEABMEKwGwPy+wE9a0GAUAEQQrsBgQsTcBK7Q2BQARBCuwNhCxLwErtCEFABEEK7AhELAAINYRtAkFABEEK7AJL7QABQARBCuyAAkKK7NAAAQJK7IJAAors0AJBQkrsUABK7EYExESsBU5sDcRshYpKjk5ObA2ErEbEDk5sC8RtB4NLCM6JBc5sAkSsAc5sQAhERKwAjkAsRAGERKxAAk5OTAxARQHMxUhNSE2NTQuASMiBiMiJjU0NxcGFRQWMzI2MzIWAxQHFhcHJyYvARYzMjY1NCYjIg4BByc+ATMyHgIBlAdu/gQBWAseJBQRbB02Sg4wDDQyHVEbOUgQjlKkHkCRrh5vJzxONScaLRMGMwhZLQ4sNSUCVA4YMzMRDxAVBwg4KxwlECIMHhYJMf7IbSEoniI6gzs+IjsrKjkfHg8SKEUPH0EAAgAB//YCNAMEACoAPwDYALIFAAArsBAvtBYEABMEK7AbL7QkBAATBCuwMS+0MgQAEwQrsC4ysDYvtD8EABMEKwGwQC+wOda0PAUAEQQrsjk8CiuzQDkxCSuzITw5CCuwEjO0HgUAEQQrsBMysDwQsQcBK7QCBQARBCuwAhCxMwErtC4FABEEK7IuMwors0AuMAkrsUEBK7EHHhEStg0QGCQnNj8kFzmwAhGyBSs1OTk5sDMSsAk5sC4RsSoEOTkAsRAFERKwBDmwFhGwAjmwGxJACQcADRIJEyAhJyQXObAkEbAqOTAxAQYVFBcHJjU0NwYHDgMjIic3FBYzMjc0JiMiBhUUFyc0NjMyFhc+ATMnMhYVMxUhNSE0KwEiJj0BMxUUFjMB4EcpLi40GTgBKx41F0ciMycPIT01MRoXAzM+KC5eCBhKKGM+Ll39zQGrOtxFMSseJAGJaGtVVRZrcjpkDUYBOyMlZBERMVswTh8NCAcVKy5OKSMs7zU9MzM/LDwvJCUbAAABAAAAPgIbAxYASgELALAWL7QiBAATBCuwMy+0CQQAEwQrsDgvsAUztDkEABMEK7ADMgGwSy+wRda0RgUAEQQrsB0yskVGCiuzQEUcCSuwRhCxNgErtAcFABEEK7I2Bwors0A2OAkrsAcQsScBK7QTBQARBCuzAxMnCCu0PAUAEQQrsDwvtAMFABEEK7IDPAors0ADBQkrsUwBK7A2GroEe8AoABUrCg6wShCwAMCxQhX5sEDAs0FCQBMrskFCQCCKIIojBg4REjkAswBAQUouLi4uAbMAQEFKLi4uLrBAGgGxRkURErBHObE8BxEStQ4WIiwzOiQXObAnEbApOQCxCTMRErITJyw5OTmwOBGzDhwdKSQXOTAxATIWFzMVIRUUMzI/ATY3HgMVFAYjIi4DJxceAzMyPgI1NCcHDgcjIiY9ASM1ITY9ATQmIwciNTQ3FwceATMBVi1CA1P+9R0QJxQNDh0nEAZmUDleOCkRBDMDHTJSLig8GwwaIgYOCg0IDQUOARY33QGWAS4+ZqUSLQ0EN1cCqTZFM68pMhsSGQwoLyEQWm9EX3xWJxEhandVIzMpDiolKAgNCggEBQIEKy2zMwMFCR8YCGYSMBExHxQAAAABAAAAQAIvAxoAQwEVALASL7QhBAATBCuwKi+0CQQAEwQrsC8vsAUztDAEABMEK7ADMrA3L7RBBAATBCuwNCDWEbQABAATBCsBsEQvsBbWtBcFABEEK7AXELEbASu0HAUAEQQrsz0cGwgrtDwFABEEK7A8L7Q9BQARBCuyPD0KK7NAPDoJK7AcELEtASu0BwUAEQQrsi0HCiuzQC0vCSuwBxCxJgErtA0FABEEK7INJgors0ANBQkrswMNJggrtDEFABEEK7AxL7QDBQARBCuxRQErsRsXERKwPjmxHD0RErAZObAtEbE3QTk5sTEHERK1AAkSISo0JBc5sAMRsQsoOTkAsSohERKxDRk5ObAJEbAmObAvErULFhcbHCgkFzkwMQEyFhUzFSMVFDMyNxYVFA4CIyIuAScXFhcmJxceARcWMzI+AjU0JwYjIiY9ASE1ITQmIyIGIyImNTQ3FwceATMyNgFoLkRV+hIyQFMnQUEjUYhFAjMWMzECMwgtGCRCDycyIh88PhUp/v4BoyUtEVQVU1ISLQ0EPT0UVAKtN0gzqSJwOXUySiURh7ZWFJFMiF4UUp0jLwscPio0GVM6GK0zLh4IOC4QMhExHRYIAAIAEgAAAlgCiwAwADkArgCyGQAAK7ASM7AnL7QABAATBCuwES+0DgQAEwQrsg4RCiuzQA4HCSuwDDIBsDovsCrWtC8FABEEK7AvELEZASuxBjEyMrQYBQARBCuwCDKwGBCxEwErsAsytBIFABEEK7ANMrISEwors0ASEAkrsTsBK7EvKhESsCw5sBkRtB0fJy0zJBc5ALEnGREStQkLFx0xOSQXObAAEbIGHyE5OTmxDhERErIkKi05OTkwMRMyNjceARc1MxEWFxEzFTMVIxEjNTQmJxEjNSYvATY3LgMnDgEjIiY1NDcXBhUWBQYHFh8BFh8BXhhPFxc+FzM5HTNUVDMgNjMypiRlbwMSCxMJD0wmKiciJBMEAP9wQx4OOw0jHAH2OCIHNiOb/tInJQF5XDP+BWo7RCv+7HRgTjhINAMWDQ4CFzIxFCYQHAwMFEcvMxQHJAkeHQAAAAEAdAA1AhUCeQA7AP0AsCQvtCUEABMEK7AHMrIkJQors0AkIgkrsC4vtAAEABMEKwGwPC+wNta0MQUAEQQrsxkxNggrtBQFABEEK7AUL7QZBQARBCuwMRCxKgErtAMFABEEK7ADELELASu0HwUAEQQrsT0BK7A2GrrsucL5ABUrCg6wERCwD8CxGhX5sBzAsBEQsxARDxMrsBoQsxsaHBMrshsaHCCKIIojBg4REjmyEBEPERI5ALUPEBEaGxwuLi4uLi4BtQ8QERobHC4uLi4uLrBAGgGxMRkRErEWNDk5sCoRtAAXIiQzJBc5sAMSsAc5ALElJBESsCY5sC4RtQMLHyo0NiQXOTAxATIWFRQOAQc+AjU0LgQnJjU0NxcGFB4EFRQGIyInNxc+AjU0LgEjIgYVFBcHJjU0PgMBDjpGDxkCFDU1GiY4LDcKiUYbLjZSXlI2j2QsKh4XICwOCyUaHiogJi0UHSMbAWdLPiErHQUDGDslHzQgHQ4RBDJKLjEmGzYoFyQqUjhNaQ4qBQcxKxANJScvGR4PIRU5HS0aEQYAAAEAIwAAAfUCOwAuAKQAsgUAACuwCC+0GQQAEwQrtBYEABMEK7ApL7QkBAATBCuwHy+0AAQAEwQrAbAvL7AO1rQTBQARBCuwExCxLAErtCIFABEEK7AiELEFASuwGzK0BAUAEQQrsTABK7ETDhESsBA5sCwRsQsROTmwIhKwFjmwBRG0AAgZJykkFzkAsRYIERKwGzmxKRkRErEOEzk5sCQRsCc5sB8SsxEQJiwkFzkwMQEyFhURIy4BIyIGIyImNTQ3FwYVFBYzMjYzMhcRNCYjIgYVFDMyNxcGIyImNTQ2AZsoMjMCR0cJTxNSUhksEkJJFj4bRiwcDxyAFAYMFhYXIx2WAjszHP4UTzkGSF81QRhAMTonBysBUw8VeiAUBSUQLxQ5lQAAAQAjAAACTANZAEcA1wCyBAAAK7AML7AJM7QXBAATBCuwGjKwKS+0JAQAEwQrsB8vtC8EABMEKwGwSC+wD9a0FAUAEQQrsBQQsTwBK7RCBQARBCuwLCDWEbQiBQARBCuwQhCxBAErsBwytAMFABEEK7A1MrADELE3ASu0AAUAEQQrsUkBK7EUDxESsBE5sDwRsBI5sCwSsAw5sEIRsBc5sCISsD85sAQRQAkJGicpLzk6QEUkFzmwAxKwMzkAsRcMERKwHDmwKRGxDxQ5ObAkErAnObAfEbcAAhIRJiw1NyQXOTAxARQHESM0LgIjIgYjIiY1NDcXBhUUFjMyNjMyFxE0IyIGFRQzMjcXBiMiJjU0NjMyHgMVNjU0LwEmNTQ2NxcGFRQeAwJMVzMKGz4uD0QWVFEZLBIyQh1UFUQuKxx/FAkHFxQcGyObNxkjEgkCJVytWhwlHCpJaGlJAflXKP6GFigvHAZHX0E1GEAxLzEGKwFUI3giEAcrDycdOJQSFygbFREwOiY5KEQZJBwpGBYhKhsiSQAAAQAXAD4B+AIaADIAfwCyMQEAK7QmBAATBCuwCi+0GQQAEwQrsCAvtCEEABMEKwGwMy+wLta0KQUAEQQrsCkQsRwBK7AjMrQFBQARBCuwADKxNAErsRwpERK1ChkhKywxJBc5sAURsAI5ALEgGRESsQUcOTmwIRGyAh4sOTk5sCYStBIAEysuJBc5MDEBFAceARUUDgIjIi4FJzceBDMyNjU0JwYHJzI1NCYjIgYVFBcHJjU0NjMyAfYvIBEiMikOKEg3NSUpGhIzCR01PFUtKjgpHCIKbzQoJ1UqFEl6PIgBnkYfICsgKj0dDBonQz1fRDQQI1FuVjw0KTAnCQMyXhsiNBghEi4hQDRLAAEAFwA+AlEDXQBMAKMAsjEBACu0JgQAEwQrsAovtBkEABMEK7AgL7QhBAATBCsBsE0vsEDWtEUFABEEK7AuINYRtCkFABEEK7BFELEcASuwJDK0BQUAEQQrsDQysAUQsTgBK7QABQARBCuxTgErsRwpERJACgoZISssMTxCQ0kkFzmwBRGxAzY5OQCxIBkRErEFHDk5sCERsgMeLDk5ObAmErcSABMrLjQ2OCQXOTAxARQGBxYVFA4CIyIuBSc3HgQzMjY1NCcGBycyNjU0IyIGFRQXByY1NDYzMhYVFAc2NTQuAycmNTQ3FwYVFB4FAlFQNSwiMikOKEg3NSUpGhIzCBkzPFkwKzcpHCIKPzBjI1IqFEl6PDRUDjYwUFVcGyJGHTAoQU5OQSgBzz9PCyZCKj0dDBonQz1fRDQQH0xxWEA0KC8pCQMyMC88NBghEi4hQDRLNT0MIwtLLz8jGScZHyYuMSYeGBcjGBghLEoAAgABAAACOQIuACMAKgCUALIeAAArsBEvtBYEABMEK7AkL7AcM7QCBAATBCuwCTKwBC+wBzO0BQQAEwQrAbArL7Ae1rECJDIytB0FABEEK7AIMrIeHQors0AeBAkrsB0QsRkBK7QOBQARBCuyDhkKK7NADgcJK7EsASuxGR0RErEREzk5ALERHhESsR8qOTmwFhGwEzmwJBK0DgAUIickFzkwMRM2NzUhNSEVIxUeAxUUBiMiJzcWMj4BNTQmIxEjNS4CJzcOAQceARccepn+0gI41xY2SDAvIikoIBwcEgVbNjMJRXU2+SKVESmJFgFDYCouMzMuAhEmTjQjQiUnGRgXCDZN/mZYF09NAo0HRhMHWC8AAQAcAAAB0wKEACsAqgCyDQAAK7ARL7QSBAATBCuwGy+0JgQAEwQrsAsvtAgEABMEK7IICwors0AIBgkrAbAsL7Ae1rQjBQARBCuwIxCxFwErtAAFABEEK7AAELENASuwBTK0DAUAEQQrsAcysQoF6bEtASuxIx4RErAgObAXEbUREgMbISkkFzkAsRENERKwBTmwEhGwAzmxJhsRErEWADk5sAsRsxcYHiEkFzmwCBKxICk5OTAxARQGBxYXETMVMxUjESM1LgEvAT4DNCcOAQciJjU0NxcGFRQWMzI2Nx4BATdXJExkMzQ0MxKvOhQQMzoqGxs0KCUxFigLFQ8bJh8nPQGmNUYHHGEB3VYz/gVSLIcGMQEOGi00GjUpAiofJRkXERIIEi9EEUoAAQArAAMB4AJ7ACsApACwIy+0FgQAEwQrsxMWIwgrtCYEABMEK7AOL7AIM7QABAATBCuwBjKyDgAKK7NADgsJK7IADgors0AABAkrAbAsL7Ap1rQRBQARBCuwERCxIQErtBkFABEEK7AZELELASuwAzK0CgUAEQQrsAUysQgF6bEtASuxIRERErUOABYdHiYkFzkAsSMmERKyGQwhOTk5sRYTERKxESk5ObAOEbADOTAxEzIWFzUzFTMVIxEjESYjIgYVFDMyNjMyFhUUDgEHJz4BNTQjIgYjIiY1NDbFOU0uMzQ0M1ZeIUYLCU8IIiwmIicqHUkgBE4NGiBXAjE1SMdNM/4IAWCbNyMQGikiEjUiJSAbTwkYHyUcMV4AAAAAAgABAAABtQIuABEAJQCJALIbAAArsCMvtAAEABMEK7AVL7EMGDMztBYEABMEKwGwJi+wEta0DwUAEQQrshIPCiuzQBIVCSuwDxCxGwErsAsytBoFABEEK7IaGwors0AaGAkrsScBK7EPEhESsRQgOTmwGxGyHyEjOTk5ALEjGxESsgQLIDk5ObAAEbADObAVErECEjk5MDETMjcXBx4FFxEjBhUUFic0NyM1IRUjESM1LgEvATcGIyImsiYgIYECJg8nHCkU3hpBdBI1AbQzMxuEShBOBwsmSAGTICR/AQ0HFBQjFgFhGBgeGjEeGTMz/gVBQVoMKFICOAAAAgAJAAMBvwINADgAQgDSALI3AQArsAMztDwEABMEK7AdL7QoBAATBCuwMC+0EwQAEwQrsA0vtEEEABMEKwGwQy+wIta0IwUAEQQrsCMQsTIBK7QRBQARBCuwERCxKwErtBoFABEEK7MIGisIK7Q5BQARBCuwOS+0CAUAEQQrsUQBK7EjIhESsDY5sDIRsDc5sBESsAA5sDkRtgMNFh0oMD8kFzmwCBKxFy05OQCxMCgRErArObATEbAaObANErMRFy0yJBc5sEERsQ80OTmwPBKzCCIjACQXObA3EbA2OTAxEz4BMzIeAhUUDgIjIicGFRQzMjY/AR4BFRQGIyIuAic3HgMzMjY1NCcOASMiNTQ3Jic3Fhc0JiMiBhUWMzKdCUk0Ch8nGh8uJw4sGwM2FzkEKCMpWko+Z0AmBzMIIjVSMDwzJQs9IW8DIz4oHeQfGB88GSRVAageRQcRJBgcKRUJEBIZVzweBxZQLUpjTXyDQgpAeWtBRS4wLCI0lBkhGlcfPhgSFDEgDQAAAgAAAAIBlwIuAAgAHAByALAcL7QABAATBCuwDS+wEDO0DgQAEwQrAbAdL7AL1rQABQARBCuwETKyCwAKK7NACw0JK7AAELEEASu0GQUAEQQrshkECiuzQBkQCSuxHgErsQALERKwCTmwBBGwFTkAsQAcERKwCzmwDRGxCBk5OTAxNzI+ATU0LgEnAyYnESM1IRUhFR4BMhYXFhUUBiN7I2JETGcWBxoSSAGX/uQiTDY6Ewu6RzVZaRkUFyAb/owOFwHUMzM9LigTGhEYTMQAAAIAAP+1Af0CLgAvADoAtQCwDy+0EAQAEwQrsBovtDAEABMEK7A2L7QoBAATBCuwHy+wIjO0IAQAEwQrAbA7L7Ad1rQ5BQARBCuwIzKyHTkKK7NAHR8JK7A5ELEzASu0FwUAEQQrsBcQsRQBK7QABQARBCuyABQKK7NAACIJK7E8ASuxOR0RErEQDzk5sDMRsBo5sBcSsQUnOTmwFBGwKDkAsRAPERKwBTmxNjARErMAFBc5JBc5sCgRsCo5sB8SsDg5MDEBFA4CBx4EFwcuASM1MzI2NTQmJw4BIyImPQEjNSEVIRUeAR8BMh4FBTI2NTQnIyInFRYBjyU4LxQkMjIURA4iOclyR1d3JS4HXDMeMCUB/f5bFE1MCgoRGxYZEAv+5h1DEBwxIA4BHyA7KRkHDRYlDz4NJEB0M1wyJhwHP14uFuEzMxUhHwcBAQYKFBkoL0saEQEmhhcAAAEAAP/9AlkCLgBAAPcAshYAACuwLi+0OgQAEwQrsjouCiuzQDozCSuwAC+0JQQAEwQrsBovtA4EABMEK7AHL7AKM7QIBAATBCsBsEEvsDPWtDQFABEEK7A0ELEEASu0IgUAEQQrsgQiCiuzQAQHCSuwIhCxPQErtCsFABEEK7ArELEYASu0EwUAEQQrshMYCiuzQBMKCSuzFhMYCCu0FQUAEQQrsUIBK7E9IhEStgAGHwsoLjokFzmxGCsRErAOObETFhESsBo5sBURsBA5ALEuFhESsBU5sQA6ERKzExgrPSQXObAlEbA/ObAaErIEIig5OTmwDhGwETmwBxKxEB85OTAxNyIuATU0NyM1IRUhHgEzMjcXBhUUFwcmNTQ3Ii4CJw4BFRQWMzI/AR4BFRQGIyImJyY1MxQeAzMyNjU0JwbzKDMNS9YCWf7SF0s5EjwZMR0wICNCUDIYEhwkGR4qEyUsGFNBSIMSBzMdKDQmESJAHCj4Mi4RYTEzMzcnBCFrbUhUD2pOXVgLISEjDUIhEi0iCCcpITNfjngrRlN9QSkKNickGCYAAAAAAgABAAECMwKGAB0AJAB+ALAeL7QCBAATBCuwBC+wDjO0BQQAEwQrsAwysgQFCiuzQAQXCSuzQAQRCSuyBQQKK7NABQoJKwGwJS+wF9axAh4yMrQWBQARBCuwBjKyFxYKK7NAFwQJK7AWELERASuwCTK0EAUAEQQrsAsyshARCiuzQBAOCSuxJgErADAxEzY3NSE1IREWFxEzFTMVIxEjNS4BJxUjNS4DIzcOAQceARcccKH+1AFfIDYzSkozFBooMwgrQFkr9xmdFSmIGgFDYSwrM/7OEUEB3Fgz/j0aHhkbo1cROD8tkAJLFQdWMQAAAgAaAAAC6wI6AEMAWQEHALIJAAArsA8vtBkEABMEK7AEINYRtEoEABMEK7BPL7RUBAATBCuwLyDWEbQqBAATBCuwRC+0PwQAEwQrsCIvtDYEABMEKwGwWi+wEda0FgUAEQQrsBYQsTMBK7QnBQARBCuwJxCxCQErsB4ytAgFABEEK7E5RjIysAgQsUwBK7BXMrQCBQARBCuwQjKxWwErsRYRERKwEzmwMxGyDxQZOTk5sQknERK0DBwtLzYkFzmxTAgRErIEP1E5OTmwAhGwADkAsUoPERKwHjmxTxkRErUCFgdHTFEkFzmwLxGwETmwVBKxLQA5ObAqEbBGObBEEkAJFCcTLDM5O0JXJBc5sD8RsDw5MDEBFhUUIyImJxUjNCYjIgYjIjU0NxcGFRQWMzI2MzIXETQmIyIOAhUUFjMyNxcGIyIuATU0NjMyFhU2Nz4CMzIWFRQnIgcVHgEyNjU0JiMiBzUWMzI2NTQmArswZyxbFjNFRwlnIX0YLxQ2ORhgGjosEgkfQCobCwkWDCIjIQsdH58qNyUFCCEfLxssPWo3Xy1YOBQzJRkODhcnLygBMjQwZ0MeyEk6A6FFOQpDPDkqAiMBUwsXKTUuCAsQESQgCSQdPo1BYgUIIRwWPi00bHhFNDkZHCEsBDMDJR8dGwAB/9EARgGRAycAMgDaALAaL7QJBAATBCuwDi+0EwQAEwQrsB8vsAUztCAEABMEK7ADMgGwMy+wK9a0MAUAEQQrsDAQsR0BK7QHBQARBCuyHQcKK7NAHR8JK7AHELEMASu0FgUAEQQrsCMg1hG0AwUAEQQrsgMjCiuzQAMFCSuxNAErsDYaugSXwCoAFSsKDrAyELAAwLEmFvmwJcAAswAlJjIuLi4uAbMAJSYyLi4uLrBAGgGxMCsRErAtObAdEbAuObEMBxESshETGjk5ObAjEbAhOQCxDgkRErEQFjk5sBMRsBE5MDETMhYVMxUhERQzMjY1NCMiByc2MzIWFRQOASMiJjURIzUhNjU0JwciLgI1NDcXBhUUM/4uSRz+5h87ZB4OGR4mISItOmM0LCdFATwFW5oNIyweISoYYQKwPEYz/rQ2jEQkECIeMSc2dlM/JwFPMwwPMgIMCRYvIB8pHSAXLgAAAAACAAAAAwGUA1QAIwAvAKQAsA0vtCQEABMEK7AbL7AFM7QcBAATBCuwAzIBsDAvsB/WtAAFABEEK7MuAB8IK7QQBQARBCuwEC+0LgUAEQQrshAuCiuzQBAbCSuwABCxGAErtCkFABEEK7ApELEnASu0CgUAEQQrsgonCiuzQAoFCSuxMQErsR8QERKwEzmxGAARErUNGh0hIiQkFzmwKRGxAwY5OQCxGyQRErIKECk5OTkwMRMUFhczFSMWFxYVFAYjIiY1ND4CNz4BNTQnIzUzJjU0NxcGEzI2NTQnFA4CBxSDLzKwmUMSHWZIRlYRGTIYHxMLvqBQNiYpOjRJPA8iRzAC3yxONzNrKkVGSJBaRBYYCx8YH049JRszXUc8Rhw2/TR2QlRWGD9NQA1xAAAAAQAAADwCHAIuACQAkwCwFC+0HQQAEwQrsh0UCiuzQB0XCSuwAC+0DAQAEwQrsAUvsAgztAYEABMEKwGwJS+wF9a0GAUAEQQrsBgQsQMBK7QKBQARBCuyCgMKK7NACggJK7IDCgors0ADBQkrsAoQsSABK7QRBQARBCuxJgErsSAKERKzAA8UHSQXOQCxDAARErERIDk5sAURsQ8iOTkwMSUiJj0BIzUhFSEVFDMyNjcWFRQGIyImJzMeAzMyNjU0Jw4BARkUKN0CHP70EhVeEUtyUXF2HTMIHjFNMDtSGhRS7i4WyTMzxBZTHDNrS2vLykFybkFbMycmHT8AAQAAAAMBmAIuAB4AdgCwFC+0GQQAEwQrsAUvsAgztAYEABMEK7IFBgors0AFAAkrAbAfL7AD1rQKBQARBCuyCgMKK7NACggJK7IDCgors0ADBQkrsAoQsRIBK7QbBQARBCuxIAErsRIKERKyABcYOTk5sBsRsBk5ALEZFBESsBc5MDE3IiY1ESM1IRUhERQWFz4DNTQjIgcnNjIWFRQOAaAsJ00BmP7oDRISMzUlHg0aHio+LjlkAz8nAZIzM/5xHxMEAiA2WTEmECIhPR44gFsAAAABAD8AAAHMApEAIwB5ALIdAAArsAgvtAMEABMEK7AhL7AaM7QQBAATBCuwGDKyECEKK7NAEBYJKwGwJC+wC9a0AAUAEQQrsAAQsR0BK7AVMrQcBQARBCuwFzK0GgUAOgQrsSUBK7EdABESsgUIEDk5OQCxAwgRErAGObAhEbIFCxU5OTkwMRMUFjMyNwcGIyImNTQ+AjMyHgIXNTMVMxUjESMRNCYjIgZyLBwKCBEFCClGDh4+KR4zJhALMzU1M1kkNUABiRw/BDMBXisSMTooFScXEspjM/4FAVcrdz0AAAL/3wAmAlUCLgArAC8BRwCwDy+0IwQAEwQrsiMPCiuzQCMaCSuwGzKwKS+0CgQAEwQrsCwvtC0EABMEKwGwMC+wBda0AAUAEQQrsAAQsSYBK7QNBQARBCuxMQErsDYausDT9cEAFSsKsBouDrAXwAWxGxb5DrAdwLrC3e0UABUrCrEaFwiwFxAOsBXAsRsdCLEdCPkOsB/AsBcQsxYXFRMrusD69NoAFSsLsBoQsxgaFxMrsxkaFxMrsBsQsxwbHRMrusLD7WcAFSsLsB0Qsx4dHxMrshwbHSCKIIojBg4REjmyGBoXERI5sBk5sh4dHyCKIIojBg4REjmyFhcVERI5AEAJFRYXGBkcHR4fLi4uLi4uLi4uAUALGhsVFhcYGRwdHh8uLi4uLi4uLi4uLrBAGgGxAAURErADObAmEbMCCg8jJBc5ALEpIxESswUMDQMkFzkwMRMUFwcmNTQ+AjMyFhQGIyIuCCczHgYzMjY1NCYjIgYlNSEV/A4sFQoZOCZLY2ZTHjUrIx0WFAwOBgYzCgsWEyAkMh9CTEY1Fzf+4wJ2AWEMFxknIgseJxp7vnkMGxwxJkApSSUlNztYLzocFFxJRmEhdzMzAAABAA8AAAHqAoYAMACmALINAAArsBQvtBUEAB8EK7ApL7QhBAATBCuwHC+wCjO0LwQAEwQrsAgysi8cCiuzQC8GCSsBsDEvsCzWtB8FABEEK7AfELEZASu0AAUAEQQrsAAQsQ0BK7AFMrQMBQARBCuwBzKyDA0KK7NADAoJK7EyASuxHywRErAVObAZEbUUAyUmLi8kFzkAsRQNERKwBTmwFRGwAzmxHCERErIAGSw5OTkwMQEUBgcWFxEzFTMVIxEjNS4ELwE2NzY1NCYjIgYVFDMyNzI3FQYrASImNTQ2MhYBNFwlakkzUVEzIh47LEMmLG4nQjcpID8ZAwMEAgMFCCAoVn5RAac4UAYpWQHvWDP+BUklIDUZGQY4EBEePCIqJBofAQEzAS0gMkRKAAAAAf/p//4BswIuABUAewCyEgAAK7AFL7AIM7QGBAATBCsBsBYvsAPWtAoFABEEK7IKAwors0AKCAkrsgMKCiuzQAMFCSuwChCxFAErtA8FABEEK7APELARINYRtBIFABEEK7ASL7QRBQARBCuxFwErsQoDERKwAjmxDxIRErAAObAREbAMOQAwMQEGBycRIzUhFSEVNjcXBhUUFwcmNTQBTX9jM08Byv64Z5QsLhUvGQFqD7QyASIzM+qGDiFQf09fCUxjYgAAAAACAC0AAAHNAjUAHgAlAHgAsg8AACuwDS+0CgQAEwQrsAAg1hG0GgQAEwQrAbAmL7AX1rQDBQARBCuwAxCxDwErsQkfMjK0DgUAEQQrsg4PCiuzQA4MCSuxJwErsQMXERKwEzmwDxGzFRocISQXOQCxDQ8RErYDCQgXHR8lJBc5sAARsBw5MDETIgYVFB4CFzc1MxUjESM1LgEvATcmNTQ2MzIXByYXBgcXFh8Bjw8OESMVFHmFUjNHa00ccF4pLCodJwufeVUtSjEmAgIaCg0VDwcGREoz/gVWR0sWKVsWRho9OBkeWTxJFyYrIAAAAAABAAD//gG9Ai4AHABxALIRAAArsBYvtAcEABMEK7ALL7AOM7QMBAATBCsBsB0vsALWtBoFABEEK7AaELERASuwCTK0EAUAEQQrshARCiuzQBAOCSuyERAKK7NAEQsJK7EeASuxERoRErIABxw5OTkAsRYRERKyAgkAOTk5MDE3JjU0PgIzMhc1ITUhFSMRIzUuAiMiDgEVFBdjNCM0LBBiM/6pAb0zMwcfQiQmMxAihCZEL0YiEGbMMzP+A8MaQkUtLREsIAAAAAIACQAAAfMCcwAaACYAcACyDQAAK7AYL7QbBAATBCuwJC+0AwQAEwQrsAsg1hG0CAQAEwQrsggLCiuzQAgGCSsBsCcvsA3WsAUytAwFABEEK7AHMrQKBQAkBCuxKAErALEYDRESsw4SGh8kFzmwGxGyABEFOTk5sCQSsCI5MDETPgEzMhc1MxUzFSMRIxEuAScHJzY1NCYjIgc3Mh4BFzc2NyYjIgYJCm42hUY0PT00ByoJuyQlHBYCLiUcICMKMxkjNDMdQgGjMVCC0UUz/gUBOhdICcEiJiEaJAk5CSwrMhgmKSAAAAABAAEAAAJTAi4AKACBALIJAAArsCYvtAIEABMEK7AHL7QgBAAfBCuwEy+wFjO0FAQAEwQrAbApL7AJ1rAeMrQIBQARBCuyCQgKK7NACRMJK7AIELEEASu0IwUAEQQrsSoBK7EECBESsSYoOTkAsSYJERKxCh45ObACEbENKDk5sAcStQAOEBkcIyQXOTAxARYzMjU0JiMRIzUuAS8BNjcmJyM1IRUhFhcVBgcWFxEzMhYVFAYjIicBzAkLHEk8Mx2dOB1iKCRmNAJS/jk+KDY5dksfWnI3FxQaARwJIzE//lpGQV8KJU0jNkAzMyo4JjEsJ2EBT2FQJyULAAACAAAAAAGMAi4ADgAVAFcAsg4AACuwDy+0BgQAEwQrsAgvsAsztAkEABMEKwGwFi+wDtaxBg8yMrQNBQARBCuyDQ4KK7NADQsJK7IODQors0AOCAkrsRcBKwCxDw4RErEEFTk5MDElLgEjJzY3NSE1IRUjESMRDgEHHgEXASoOlk0hfpT+1gGMLzMbkxUliBZZKoo2YisrMzP+BQGdBUkVBVgsAAIAAABHAjUCLgAsADAAjgCwCS+0EwQAEwQrsBovtCoEABMEK7AlL7QgBAATBCuwDzKwLS+0LgQAEwQrAbAxL7AP1rQQBQARBCuwEBCxHQErtCgFABEEK7AoELEWASu0BgUAEQQrsTIBK7EWKBEStQAJExogIiQXOQCxGhMRErAGObAqEbAWObAlErIdIxg5OTmwIBGyABAiOTk5MDEBHgQVFAYjIi4DJxceATMyNjU0JwYjIiY1NDYzMhcHJiMiBhUUMzI2JTUhFQGlEg4lEhBgSzliQzoiEDkllFQsUCI1UjNPKR8UNA4hDgwUSyUz/nwCNQGuDAsjITkgQHMxSm1fOhaTpVE/Mx9aNz8jMB4wGxMWOjKUMzMAAAAAAgABAAABygIuABoAIQB0ALILAAArsBUvtBQEABMEK7AFL7EIGzMztAYEABMEKwGwIi+wGda0EgUAEQQrshkSCiuzQBkFCSuwEhCxCwErsCAytAoFABEEK7IKCwors0AKCAkrsSMBK7ELEhESswAUFRskFzkAsQUUERKyDxkgOTk5MDETLgEnNSM1IRUjESM1NCYjIgYVFBcHIyImNTQ3HgEXFhc1xQ8+TikByTMzYCNCMlUXBClEPj03ETkuAYEmIREiMzP+Ba0fgUMrUBAsXSyJlhU4MhNO4AAAAAIAAAAAAbECLgAQAB4ASwCyDAAAK7AGL7EJETMztAcEABMEKwGwHy+wDNawHTK0CwUAEQQrsgsMCiuzQAsJCSuyDAsKK7NADAYJK7EgASsAsQYMERKwHTkwMRM2Ny4BKwE1IRUjESM1LgEnEx4EFwYHHgIXESk5WRdlCTYBsTMzKZM5PwMcEhsWCFk3P0oiMQEjOUMXRTMz/gVMQ1IKARACEw4XGQ5GNxQnHzIBagD//wAAAAABjAIuECcGCgGsAKgQBgYAAAAAAQABAAAB/AIuACYAogCyGgAAK7AEL7QDBAATBCuwJC+wHjO0CgQAEwQrsA4ysBQvsBcztBUEABMEKwGwJy+wB9a0AAUAEQQrsAAQsSEBK7QgBQARBCuwIBCxGgErsBIytBkFABEEK7IZGgors0AZFwkrshoZCiuzQBoUCSuxKAErsSEAERKyAwQKOTk5sCARsAw5sBoSsA45ALEkAxESswcSGyEkFzmwChGwDDkwMRMUFjMHIiY1NDYzMhc2MzIeARc1ITUhFSMRIxEuASMiFQc0JiMiBlYrOBI+Rkc7MS4WKxcmEAT+awH7MzMJMxclJzkXIy4BJSY7MFM+QFIwKxoYDIczM/4FARQhSkwIMCk1AAAAAQAAAAACBgKFADYArwCyJgAAK7A1L7QwBAATBCuwAyDWEbQIBAATBCuwDi+wIzO0EwQAEwQrsCEyshMOCiuzQBMfCSuwDhCwKiDWEbQXBAATBCsBsDcvsAvWtC0FACYEK7AtELEmASuwHjK0JQUAEQQrsCAytCMFACUEK7E4ASuxLQsRErEAFTk5sCYRsTM1OTkAsQg1ERKxBTM5ObEqMBEStQALBh4VMiQXObAOEbAQObETFxESsBE5MDETDgEjIic3FjM+ATU0JiMiBzU2MzIXNjMeBRc1MxUzFSMRIxE0JiMiBhUUFjMyNxcGIyLJDDQcJB0aExUXGUU1EhIRFIkSGk4OFw4VCBwFMzo6M1EkFyEsERAQGBogPAFYGyYdKRMFLRExPQc4AmtfAgkHFwkkB8BXM/4FAV4ecy82HRwLKxMAAwAAAAABvQIuAA8AFgAaAFEAsgkAACuwAy+xBhczM7QEBAATBCsBsBsvsAnWsRAZMjK0CAUAEQQrsggJCiuzQAgGCSuyCQgKK7NACQMJK7EcASsAsQMJERKyEhYZOTk5MDETJicjNSEVIxEjNS4BLwE2FyYnBgcWFwMWFzXALX4VAb06M0JkRSoe9x1JOzB8VdZMigGXI0EzM/4FQF1HAjolMyg/KzcOcQFjH3uaAAACAAAAAAH8Ai4ACAAoAGYAshQAACuwHS+0JgQAEwQrsBgvtAUEABMEK7AOL7EAETMztA8EABMEKwGwKS+wFNawBzK0EwUAEQQrshMUCiuzQBMRCSuxKgErALEYJhEStBUHGx8gJBc5sAURsAM5sA4SsAw5MDETHgEXNjMyFzUHLgEnNSM1IRUjESM1LgEjIg4CIyInNx4EMzI2c0A1Eh8iJzLEC0JfJAH8NTMLOhYVJxszHzBBLAQSCA4OCBQtAfsaODQdRa64SzcUIjMz/gX1HE40PzRqGAciDBMHRQAAAAIAAf/LAfECLgAfACMASwCwFS+0AAQAEwQrsCAvtCEEABMEKwGwJC+wHda0GAUAEQQrsBgQsRIBK7QDBQARBCuxJQErsRgdERKwGzmwEhGzAA0FGiQXOQAwMRMyFhUUBxYXByYvARYzMj4CNTQmIyIGFRQXByY1NDYnNSEV5jZslaVZJqnZFl86JjocDU0kG0IbHzBktgHJAetZOm8yW3Ahukg5IRwoIwwkPCIlEhcqHjkrSxAzMwAB/sf/ef83/+kACgAqALIDAAArtAgEABIEK7IDAAArAbALL7AA1rQGBQAkBCu0BgUAJAQrADAxBTQ2MzIWFAYjIib+xyIWGR8fGR4aTx4aHzIfIgABAAD/ywHnAi4AJABxALAYL7QjBAATBCuwAC+0AQQAEwQrAbAlL7Ag1rQbBQARBCuyIBsKK7NAIAAJK7AbELEjASu0AwUAEQQrsAMQsRUBK7QGBQARBCuxJgErsRsgERKwHjmwIxGyGBAdOTk5sAMSsAg5ALEjGBESsAM5MDERNSEVHgEVFAcWFwcmLwEWMzI+AjU0JiMiBhUUFwcmNTQ2MzUBEC1BlaVZJqnZFl86JjocDU0kG0IbHzBkLwH7M04SSytvMltwIbpIOSEcKCMMJDwiJRIXKh45K0sQAAAAAAH/sQAAAMECewAQAEsAshAAACuwBC+wDTO0BQQAEwQrsAsysgUECiuzQAUJCSsBsBEvsBDWsAgytA8FABEEK7AKMrQNBQAaBCuxEgErALEEEBESsAg5MDETLgErATUzMhc1MxUzFSMRI0wPKRFSYhseM0JCMwGxHC4zOIVNM/4FAAAAAAEAAAAAAh0DFQAZAGcAsgkAACuyFwMAK7QRBAATBCu0DAsJEQ0rsAYztAwEABMEK7AEMgGwGi+wCda0CAUAEQQrsggJCiuzQAgGCSuyCQgKK7NACQsJK7EbASuxCAkRErECBDk5ALEXDBESsg4UFTk5OTAxEx4CFzMVIxEjESM1Myc+ATMyFhcHJiMiBkICCBgQSUMzRzkqCoBEWJJWI5GKQlUCZQQIGBMz/gUB+zM6SWROSiaLVwAB/ncAAAC0AykAJACgALIIAAArsgsBACuwAzO0CgQAEwQrsAUyshoBACuzGgoLCCuzHhoKDiuwIC+0FAQAHwQrsA8vtAAEABMEKwGwJS+wIta0EgUAEQQrsBIQsQgBK7AMMrQHBQARBCuwAzKyBwgKK7NABwUJK7IIBwors0AICgkrsSYBK7EIEhESsgAYIDk5OQCxCxoRErAbObAgEbEYHTk5sQ8UERKwIjkwMQMyFhczFSMRIxEjNTMuASMiBhUeAhcWFRQHJzY3LgEiJjU0NtGGniBBQTNAQBKXZixbD4BvEQkYLRQFB0CQSGkDKY5tM/4FAfszUnYkGgUDGSASGBUqERQVIRMcJCVIAAAAAAL/Bf8qAGkATAAYACIAXwCwEy+0GwQAEwQrsCAvtAAEABMEKwGwIy+wFta0GQUAEQQrsBkQsQQBK7QJBQARBCuxBBkRErMABhMeJBc5sAkRsQcROTkAsSAbERKyCxYROTk5sAARsgIECTk5OTAxJzIXNjU0JzcWFRQHHgEXByYnBiMiJjU0NhcUMzI2NyYjIgaaGDABDCoVBDooKSgwTTk8ICovBCkWHAUWHRMaFRkFBQ4fGT8VDw8vKjgfQkE5LyIXOVMbGw0TEQAAAAH/QP7uAJoAJAAXAEAAsgMAACu0CQQAEwQrsBUvtA4EABMEKwGwGC+wANa0DAUAEQQrALEOFRESsBM5sAkRsgAHEDk5ObADErAGOTAxBzQ2Myc3FwcmIyIGFRQzMjcXBycGIyImwEIxCC4XHhgNGSErMSijIIgpMyYwYik1FhI/IgYXEyEjjSZyFS8AAf6e/tv/rQApAAYAEgABsAcvsADWtAUFAAgEKwAwMQU/ARcHFwf+npEQK2SnEnNqMlFHfjgAAAAB/t/+1AAvAIMADAAABTcnPwEXBxcHJwcXB/7fei99ECtQnRKQRp0ShV8hVjJRM3Q4YjZzOAAAAAEAAQAAAS8CLgAWAFIAsgcAACu0AAQAEwQrsA4vsBEztA8EABMEKwGwFy+wCta0FAUAEQQrshQKCiuzQBQRCSuyChQKK7NACg4JK7EYASsAsQ4AERKzAwUKFCQXOTAxNzI2NxYXBiMiJjU0NjcjNSEVDgEVFBbHFhYUDRsbQ0xeTzyxASZbckQzDBgLEjqKZkucJDMxG5tuNXEAAAH/xgAAAUwDEwAsAKUAsigAACu0IQQAEwQrsAQvsBsztAUEABMEK7AZMrAKL7QTBAATBCsBsC0vsA3WtBEFABEEK7ARELEAASu0HgUAEQQrsgAeCiuzQAAECSuwHhCxBgErtBkFABEEK7IZBgors0AZGwkrsS4BK7ERDRESsA45sAARsQoPOTmwHhKxCRM5ObAGEbMDFiEoJBc5ALEEIRESsgAkJjk5ObETChESsAw5MDE3NDY3IzUzNCYrASImNDcXBhUUMzI2MzIWFzMVIwYVFBYzMjY3FhcGIyIuAihHQbDSLVkpKjMVLA4yDUsEQDwCRz6zPTAVGBINGxtDMEgiD+pRkS8zNBgySB8YHwsjAzZNM2qgQH4NFwsSOjlURAAAAP///jYAAAGiAnsQJwYMAOEAABAHBhP+NQAAAAD///5KAAABowM0ECcGGQDIAAAQBwYT/kkAAAAAAAH/L/9a//P//QADAB4AsgIAACu0AAQADQQrAbAEL7AB1rQDBQALBCsAMDEHJzcXK6YepqZ7KHsAAQALAAMBkQIxADMAcACwJC+0LwQAEwQrsAAvtB4EABMEKwGwNC+wG9a0AwUAEQQrsAMQsTIBK7QhBQARBCuwIRCxFAErtA8FABEEK7E1ASuxMgMRErQNGB4kKSQXObEUIRESsBI5sA8RsBE5ALEALxEStAMbISkqJBc5MDETIgYVFB4HFxYVFAcnNjU0LgInJjU0NjMyFhUUBiMiLgInNx4DMzI2NTSiKzkGDwwdDyYOLQafDzAMSltnEDdfRzpPQyMNGiYgCS8BBg8eFBYcAf44LQ8cGBIUDBMGFAJMaQk0DCwFI0gvNQ4uUEJUQTQoOAcVNCcNCRUfFCARPgAAAAH+7AACANsDNAAfAH4AsA4vsAkztA8EABMEK7AHMrAWL7QABAATBCuwAzIBsCAvsBnWtB4FABEEK7AeELEMASuwEDK0CwUAEQQrsAYysgsMCiuzQAsJCSuyDAsKK7NADA4JK7EhASuxHhkRErAbObAMEbMDExYcJBc5sAsSsAU5ALEAFhESsBM5MDEDMjYzMhYfATMVIxEjESM1Mzc0JiIGIyImNTQ3FwYVFGMpQhAmRwICUlIzVlYCMyhCG2BUGioRArEFNCgsM/4HAfkzJBsXBjYzISwaGhg3AP//AAD/kAIcAi4QJgX2AAAQBwYKAjEAF///AAD/bwGYAi4QJwYKAa7/9hAGBfcAAP//AAAAAAGxAi4QJgYDAAAQBwYKAbkAngACABP/AwJSAosABQA6AL4AshkAACuyHgAAK7AyL7QHBAATBCuwFy+0FAQAEwQrshQXCiuzQBQSCSuwDTIBsDsvsDXWtDoFABEEK7A6ELEkASuxAAwyMrQeBQARBCuwDjKwHhCxGQErsBEytBgFABEEK7ATMrIYGQors0AYFgkrsTwBK7E6NRESsDc5sCQRtgIfIygqMjgkFzmxGR4RErEhIjk5ALEyGREStgAPEQUdJCgkFzmwBxGyDCosOTk5sRQXERKzLzU4OiQXOTAxAQYHHgEXADI2Nx4BFzUzERYXETMVMxUjESM1NCYnEQcWFwcnNzUmLwE2Ny4DJw4BIyImNTQ3FwYVAUhwQ0Q5Nv7+ME8XFz4XMzkdM05OMx83ZHM0Ev2ZMqYkZW8DEgsTCQ9MJhg4ISQSAa8vMyMoOAEsOCIHNiOb/tInJQF5XDP+BWk9Qyv+7EdUKjiyalVgTjhINAMWDQ4CFzIhJCYQHA0MAAEAdP7zAoACeQB1AXkAsGAvtGUEABMEK7BrL7QABAATBCuwFi+0FwQAEwQrshYXCiuzQBYUCSuwIC+0LgQAEwQrAbB2L7Ao1rQjBQARBCuzRyMoCCu0QgUAEQQrsEIvtEcFABEEK7AjELEcASu0MQUAEQQrsFIysHMg1hG0bgUAEQQrsDEQsWgBK7A5MrQDBQARBCuwTTKwAxCxCAErtFoFABEEK7F3ASuwNhq67LnC+QAVKwoOsD8QsD3AsUgV+bBKwLA/ELM+Pz0TK7BIELNJSEoTK7JJSEogiiCKIwYOERI5sj4/PRESOQC1PT4/SElKLi4uLi4uAbU9Pj9ISUouLi4uLi6wQBoBsSNHERKxJkQ5ObAcEbQSFiUuRSQXObBzErE0NTk5sDERsWJxOTmwbhKxUGM5ObBoEbUMAFRgZXAkFzmwAxKxBVU5OQCxZWARErBiObBrEbUDCFoFcXMkFzmxFgARErMMElJVJBc5sBcRsFA5sCASthwmKDE1OU0kFzkwMQUyFhUUBz4BNTQnLgYnBiMiJzcXPgI1NC4BIyIGFRQXByY1ND4DMzIWFRQOAQc+AjU0LgQnJjU0NxcGFB4EFRQGBwYVFBcWFxYXFhUUDgMjIic3FjMyNjU0JiMiBhUUFwcmNTQ2Abk1LB0iLl0HLBEiEBQKASMWLCoeFyAsDgslGh8pICYtFB0jGwk6Rg8ZAhQ1NRomOCw3ColGGy42Ul5SNkJDAlQJBEcaMCAuOCgOHB0WBwYYIRYPDhETKhw0RjIhJBcFMRo5IgMRBxALERIKBQ4qBQcxKxANJiYwGB4PIRU5HS0aEQZLPiErHQUDGDslHzQgHQ4RBDJKLjEmGzYoFyQqUjgzVxgCCQspBAIZFSQ4IDMcEgYMJQMxFA4TDwwOCRQMIyYkAAAB/oH+1P+nAFQAMwCcALAbL7QgBAATBCuwJi+0MQQAEwQrAbA0L7Au1rQpBQARBCuwKRCwESDWEbQLBQARBCuwCy+0EQUAEQQrsCkQsSMBK7QABQARBCuwABCxBQErtBYFABEEK7ERLhESswkOHSwkFzmwKRGxDx45ObAjErMgGysxJBc5sAARsAI5sAUSsBQ5ALEgGxESsB05sCYRtQAFFgIsLiQXOTAxBxQHMjY1NC4DNTQ2NxcGFRQeAhUUDgIjIic3FjMyNjU0JiMiBhUUFwcmNTQ2MzIWwB0TPTJHRzIOFR0MTFpML0Q3ExcjFwcGGCEVEA4REysbNBU1LLgkGC8iHywbGigcEBUOHgsMDR0dSTUnORsLCyYDLRcPEw8MDQsUDSMoIjIAAP///m/+1ACXALoQJgYf7gAQBwYfAPAAZgACAEEAQQGjAa4ACwAaAEwAsBIvtAkEABMEK7ADL7QMBAATBCsBsBsvsBXWtAYFABEEK7AGELEAASu0DwUAEQQrsRwBK7EABhESsQwSOTkAsQMJERKxDxU5OTAxATQmIyIGFRQWMzI2JzIWFRQGIyImNTQ+AwFwQTQ+SUA0PEx0SV5rUUZgCBonRgEINT5PPDhEUuheSVhuY0sPKjguIAAAAQBNAAIBbAIsACkAWwCwAy+0FAQAEwQrsAovtAkEABMEKwGwKi+wBtawHzK0EgUAEQQrsCQysBIQsRcBK7QABQARBCuxKwErsRIGERKwITmwFxG1AwkKHCInJBc5ALEKFBESsAY5MDElFAYjIiY1NDYzFw4GFRQzMjY1NC4DJyY1NDcXBhUUHgMBbHM9LkE/MQsFEwsQCAkEMTlPFSskPQ49FCoLMUVFMbJNYzAcHzkvAQYDBQUHCQYYTT0dNC8hMQw0MA8cGQ4KFCswPWIAAAEAMf/FAeICIwAlACAAsAMvtBMEABMEKwGwJi+wFda0AAUAEQQrsScBKwAwMQEUBiMWFwcnJi8CJi8BFxYzFjMyNTQuBC8CJic3Fh8BFgGHXjJhiiJIQzM5QCEqDVInHQcRdQUMCRMHCgpIOhEnEicqhAEiNkVAfiRAOyMnJxUYPS4VAVYNFxINDgYGBSohJiMtERM/AAAAAQARACwB9AICACcAUwCwCy+0EgQAEwQrsBsvtAAEABMEKwGwKC+wI9a0HgUAEQQrsB4QsRgBK7QGBQARBCuxKQErsRgeERKzCwAgISQXOQCxGxIRErQNBg4hIyQXOTAxATIeAxUUDgIjIgM3Fx4BMz4ENTQmIyIGFRQXByY1ND4CASYSLzsxISlCRCSvYTMSK21HJDYcEgRPPiQxFxA6DBkzAgINIzRYN0FeLxUBegxDjIQCISo0Iw5EeiUaFxQxFD0NJiweAAADADkAFwGKAkMACQAXADIAcgCyEAEAK7QrBAATBCuwHS+0AQQAEwQrAbAzL7Am1rQTBQARBCuwICDWEbQIBQARBCuwExCxAwErtBoFABEEK7ANINYRtDAFABEEK7E0ASuxDQgRErcBBQoQGB0jKyQXOQCxEAERErUFChogJjAkFzkwMTYyNjU0Jw4BFRQ3PgE9ASYjIgYVFB4CFxYVFAYjIiY1NDY3LgE1ND4CMzIeAhUUBr1cPnMoPmglOgNyIkIdKyUzfmFHRVInREA9JjcvER00Mx4oSi8jQy4RQCAk3hI6HQJPMCIdLBUKKjFiOEpMPycxMxRNLyU4HA0NHDgmKzYAAAIAMQAFAbcCJQARADIAtQCwEi+0BwQAEwQrAbAzL7AV1rQEBQARBCuwBBCxCQErtCwFABEEK7E0ASuwNhq6wdfwxQAVKwoOsAAQsBDAsRsV+bAdwLAAELMRABATK7rBDvRwABUrC7AbELMcGx0TK7IcGx0giiCKIwYOERI5shEAECCKIIojBg4REjkAtQAbEBEcHS4uLi4uLgG1ABsQERwdLi4uLi4usEAaAbEsCRESsgcPEjk5OQCxBxIRErEuMTk5MDETDgIVFBYzJjU0NjcuBBMiJjU0Nj8BFwceBBc2PwEXDgUVFBcHJicG+Bo+PFdFIDQtFBYPBAoGVnlHbk0WJQMGDwkkDAsLGRMfGDIVHApOIA4JEAHODDJlODxxKDw4ZB0LEBgGKv5Ni0ddfD8oKxMYGRUHFQgFBgsuDQsaFiMsG0NFJggLBQAAAQAIABoB0wIXADEAcQCyDgEAK7QNBAATBCuwIy+0LQQAEwQrsAMvtBcEABMEK7IXAwors0AXGwkrAbAyL7Ao1rQpBQARBCuwKRCxMAErtCAFABEEK7EzASuxMCkRErIbIw05OTkAsRcDERKxIDA5ObANEbQIABMoKSQXOTAxAQ4BIyIuAicmLwEmIzcyHgQXFjI+AjMyHgIVFAYjIi4CJzceAjMyNjU0AYAKWiAbIxEIAwEBAwIrBB4pFAsCBAQHLiEPHhUJGh8VY0k+akYrBjMGPW9AMUIBTDIyGDI4KhMKIxAzEhwtKDgTLiEoIQ8gQSpad0Vvfz8JSJNtXUU/AAIAYAAeAdkCHAASADAAaQCyJgEAK7QQBAATBCuwFi+0LwQAEwQrsCEvtAMEABMEKwGwMS+wI9a0AAUAEQQrsAAQsRwBK7ALMrQtBQARBCuxMgErsRwAERKxISY5OQCxLxYRErATObAhEbEtMDk5sAMSsR4sOTkwMRMUFjsBNjM2MzYzNyY1NCYjIgYBBisBIi4CLwE1NyIGIyInNDYzMh4DHQEUMzeTNScMBg4IDgcIOAE5LyJOAUYVGAcPFgsFAgICETYcoglsNhYoLB8UFBABeB0mAQEBBAUOQ1dM/pAPFSkbFiwqJgd2PWcLHzRYOqQ3CQACACQAHwIKAh4ADAAwAG8AsBcvtAYEABMEK7AAL7AQM7QiBAATBCuxJiwyMgGwMS+wGda0AwUAEQQrsB8ysAMQsQoBK7QUBQARBCuxMgErsQMZERKwHTmwChGxFyI5ObAUErESJDk5ALEABhESsRQZOTmwIhGyDSAkOTk5MDETIgcVFBYzMj4BNTQmJQ4BIyIHFhUUBiMiJxE0JzcWHQE2MzIXNjMyFjMeATsBMj8ByyotFQ4sOxIeARgSM04jFwZkSi8lHSwkLy05Fi8nAgwGAgkCDTEQDgE4I6QIF0A+Fi8jIBoLFxQZSoZPAWccFxYbM4EcIiMCAQEQDAABABwAHgG9Aj4ANACiALAoL7QnBAATBCuzHCcoCCu0GwQAEwQrsCIvtC4EABMEKwGwNS+wK9a0JQUAEQQrsxMlKwgrtA4FABEEK7AOL7QTBQARBCuwJRCxHwErtDIFABEEK7AyELEDASu0GAUAEQQrsTYBK7ErDhESsBA5sSUTERKwETmwHxG1CBUbJyguJBc5sDISsBY5ALEnHBESsQAdOTmwIhGzHxgrMiQXOTAxJT4BNS4EJy4DNTQ3FwYVFB8BFhUUBgc/ATY1NCYjIgYVFDMHIiY1NDYzMhYdAQ4BAUgaKAMnRTZRCSYxEwUkJhdceJp3UggXBDopFSY6Fhg/Rzs3SwEBcAlJFh80JRcaAw4gIBMMLSAiCREqIy89cE5gDTMHFCAwPSshNy4yNThFbDoLAgcAAAAD/+cAAAGeAi4AAwALABwAXACyHAAAK7AAL7QUBAATBCuwFi+wGTO0FwQAEwQrAbAdL7Ac1rIABBQyMjK0GwUAEQQrshscCiuzQBsZCSuyHBsKK7NAHBYJK7EeASsAsQAcERKzAwULEiQXOTAxAQYHFxUnBwYHHgEXFS4BKwEHJzY3NSE1IRUjESMBKh05VogkDgkliBYQmjkIBiF+lP69AbdBMwGdBR5APmUVCQkFWCxYLogCNmIrKzMz/gUAAAAD/+cAAAGeAi4ABwAYACEAWgCyGAAAK7AZL7QQBAATBCuwEi+wFTO0EwQAEwQrAbAiL7AY1rEQGTIytBcFABEEK7IXGAors0AXFQkrshgXCiuzQBgSCSuxIwErALEZGBESswAOBCEkFzkwMTcuASc3HgEXNy4BKwEHJzY3NSE1IRUjESMRBg8BBgceARfSFmA6HixuGjYQmjkIBiF+lP69AbdBMx5IJycPJYgWJiZRCy4KSTcNLogCNmIrKzMz/gUBnQYkFRUPBVgsAAABABsAYgHXAmEACgAgALADL7QEBAATBCsBsAsvsADWtAoFABEEK7EMASsAMDElLgEjNTIeAxcBpDnVe02EXU0vEmLh6zM9YYmJTwAAAf/7AEkBZgIkACAAeACwFi+0CwQAEwQrsBsvsAYztBwEABMEK7AEMgGwIS+wGdawHTK0CAUAEQQrsAMysggZCiuzQAgGCSuyGQgKK7NAGRsJK7AIELEOASu0EwUAEQQrsSIBK7EOCBESshARFjk5OQCxGwsRErEOEzk5sBwRsRAROTkwMRMeAR0BMxUjFRQWFzI2NTQnNxYVFAYjIiY9ASM1MzU0JzgwHEFBHB4vRi0sNF9EOTlWVjECJBQxOUYzWi8mAlIqLhQiJzw9c0pYQjNLTgUAAAAAAQAaAGIB1gJhAAoAKwCwCi+0AAQAEwQrsgAKCiuzQAAECSsBsAsvsAPWtAQFABEEK7EMASsAMDE3MjY3Mw4EIxp33DYzEi9NXYRNlezgT4iKYT0AAQAoAEsCJgIkACAATgCwDy+0GwQAEwQrAbAhL7AX1rQSBQARBCuwEhCxCwErtB8FABEEK7AfELEDASu0BAUAEQQrsSIBK7ESFxESsBU5sAsRsgcUGzk5OQAwMSU+ATcXBgIHNT4BNTQuASMiBhUUFwcmNTQ+ATMyFh0BFAElPIUNMxPvjEAcIh8MJyUVKh4SOCgxW+kstVoJhP7uOjMrJCckLgw0FRkVEBkpETM0UDoIBwAAAQANAB0CHwI8ADEApACwDy+0AwQAEwQrsgMPCiuzQAMICSuwLy+0GAQAHwQrsB4vtCkEABMEKwGwMi+wEta0AAUAEQQrsAAQsSUBK7QgBQARBCuwIBCxGwErtCwFABEEK7AsELEIASu0CQUAEQQrsTMBK7ElABESsDA5sCARsRUjOTmwGxK1AxgPIikvJBc5sQkIERKwCjkAsS8DERKxABI5ObEeGBESsiMlLDk5OTAxNxQWMzI+AjczDgIHBiMiJjU0NjMyFjMyNjU0JiMiFRQXByY1ND4BMzIWFRQGIyciQDgXS31TNQ0zBkF/Ui0yQlkuLA0iCi45KBw3BiwNDSwhTDtoN0gTkyMgVpGoXW7RqyITRDgjHAIzKBojMxAWAhcZDycoPz04TgQAAQAXAC8AhQInAA0AHgABsA4vsAfWtAAFABEEK7EPASuxAAcRErAFOQAwMTcUFjMUIyI1ETQjNjIVaQwQJSofBkyJEw45VAFHJjdOAAEAEQAjAVYCLgAoAJ0AsB4vtBsEACsEK7AAL7QOBAATBCuwJC+0EwQAEwQrsAYvtAcEABMEK7IHBgors0AHCQkrAbApL7AD1rQMBQARBCuyAwwKK7NAAwYJK7AMELEhASu0FwUAEQQrsSoBK7EMAxESsAk5sCERsQAROTmwFxKxEx45OQCxABsRErEXITk5sSQOERK1AwwRFiInJBc5sQYTERKxBAs5OTAxNyImPQE0IzU2MzIdARQzMj4CMzIWHQEUFxQzFQYjIiY9ATQjIg8BBmwgHh0VECsMEx8XMiIXGwEZFRASFgoLFBIqmjET7iYzCU78Fz9NPykixwsEEjMPNCnOFzUxZQAAAAACACsAkgGHAekAEgAlAEoAsBMvtAAEABMEK7AIL7QeBAATBCsBsCYvsBjWtA4FABEEK7AOELEDASu0IwUAEQQrsScBK7EDDhESsRMeOTkAsQgAERKwIzkwMTcyNjU0LgIjIg4DFRQeAhciLgI9ATQ+AjMyHgIVFAbYMUsbKSEMHzIcEgYeLCMMMUckEBEjRy8eOTgjYMVQKCMzGAsVHSQbCSIzGAozIDU1HAUTNDwpDyJDLlFkAAAAAgADAXQCDALZABkAJABaALIMAwArtA0EABMEK7ATL7QGBAATBCuyBhMKK7NABhkJK7AdL7QiBAApBCsBsCUvsB/WsRoF6bEmASuxGh8RErETBjk5ALEiHRESsgIJEDk5ObANEbAKOTAxEx4EMzI2PwE2MxciDgMjIi4DJxcUBiMiNTQ2MzIWNgQSEx4uHSxPKyY/NAUYMzQ8WDMQHjEqLA78HhcvGxYVHgJCBy0mKRhVRDhhMz9aWj8FGClRNyQTHTIWGxwAAAABADH/TgFYASoAEgAuALACL7QABAATBCsBsBMvsBDWtAUFABEEK7IFEAors0AFAAkrsAIysRQBKwAwMRMwFSIGFRQXHgEXByYnLgE1NDbSLUEsHZMYJMMIGx1bASozNygzKx2RGSXDCBxKHzpSAAAAAv68ApEAAAOEAAoAHQBaALAVL7QLBAAfBCuyCxUKK7NACxIJK7AYMrAGL7QABAAdBCsBsB4vsBjWtBkFABEEK7AZELEJASu0AwUAMAQrsAMQsREBK7QSBQARBCuxAwkRErELFTk5ADAxAzIWFRQGIyImNDYXMj4DNzMOASMiJjUzHgOjFR8lDxceHhgcLxsVCAIdAVlISlgcAgwcNwOEHhccGB4sH7kWHygbDFJsa1MPJTAgAAAAAAH/dwLPAAADWAAKACoAsAkvtAMEAA8EK7QDBAAPBCsBsAsvsADWtAYFAA8EK7QGBQAPBCsAMDEDNDYzMhYVFAYiJokwFBUwIUggAxMkIR8mFDAwAAQAMAAnASgCbQAOABsAKwA4AHsAsCQvtDYEABMEK7AvL7QcBAATBCuwBi+0GQQAEwQrsBIvtAAEABMEKwGwOS+wJ9awCTK0MwUAEQQrsBUysDMQsSwBK7APMrQhBQARBCuwAzKxOgErsSwzERK1BgASGRwkJBc5ALEvNhESsSEnOTmxEhkRErEDCTk5MDETMhYVFAYjIiY1ND4DFzQmIyIGFRQeATMyNgcyHgIVFAYjIiY1ND4CFzQmIyIOARUUFjMyNqwyR0M4NEYFERouZTIVJiQKIhshKUMMIyseQzg2RAoYNmsuGAweICkdKCICbUQ4NkREOAkaJB4VeyYiMxULHR8otwoYNiU1Q0M4DSMsHnwgKQojHB8nKwAAAf/5AAADaAKBAD4AdgCyDwAAK7AzL7AMM7Q0BAArBCuwCjIBsD8vsDDWtDsFABsEK7A7ELEaASuxEAErsAkytA0FABsEK7INEAors0ANDAkrsUABK7E7MBESsCY5sBoRsD05sBASsgAfITk5OQCxMw8RErMJBjs9JBc5sDQRsAA5MDEBMh4DFzY/ATUzFSMRIxEHDgQjIiY1ND4CNSYnBg8BDgIjIiY1ND4CNTQrATUzMh4DFzY3NgGTCBYfGhcENis7x4ZBTi83Eg4fIBcnJCskFB9CSjsPFR8mGSAZHxlHOFwIEx0XEwIVPl0CUAsiM1s5JxMX1EH9wAFpIBhKRT4mFRgeOSlIK4seJldJF103HRcWLyQ7IrBBCR4vWDgQRGEAAAH/+QAABFACgQBCAJEAshMAACuwNy+xDBAzM7Q4BAArBCuwCjKyNzgKK7NANw8JKwGwQy+wNNa0PwUAGwQrsD8QsR4BK7EUASuwCTK0EQUAGwQrsBEQsQ8BK7QOBQAbBCuyDg8KK7NADgwJK7FEASuxPzQRErAqObAeEbBBObAUErIAIyU5OTkAsTcTERKzCQY/QSQXObA4EbAAOTAxATIeAxc2PwE1IRUjESMRIxEjEQcOBCMiJjU0PgI1JicGDwEOAiMiJjU0PgI1NCsBNTMyHgMXPgIBkwgWHxoXBDYrOwGvnkCQQU4vNxIOHyAXJyQrJBQfQko7DxUfJhkgGR8ZRzhcCBMdFxMCDllXAlALIjNbOScTF9RB/roBRv3AAWkgGEpFPiYVGB45KUgrix4mV0kXXTcdFxYvJDsisEEJHi9YOAphSgAC/+AAAAN0A4QALQAyAOQAshgAACuwITO0DwQAHwQrsg8YCiuzAA8UCSuwCi+0MAQAHwQrsCQvsgcfLjMzM7QlBAArBCuwBTKwAy+0KgQAHwQrsgMqCiuzQAMtCSsBsDMvsCLWsCYytCEFABsEK7AFMrIiIQors0AiJAkrsCEQsR8BK7QuBQAbBCuwLhCxAAErtC0FABsEK7AtELExASu0CQUAGwQrsBUysgkxCiuzQAkHCSuxNAErsR8hERKxAxs5ObAuEbEMKjk5sS0AERKwHTmwMRGxGA85ObAJErESEzk5ALEKDxESsBs5sDARsB05MDEBNCYjIhUhFSMVIyIHHgEzMj4CMhUUBiMiJic2NyYnIxEjESM1MzU0NjMyFhUHFhczNQGOQDZ7AteIaetZE6RLJD4hHQxjNlzqHBScdw6AQH19cF45aXEte6kCzjlAxkHzjiFmHSMdDChhc0lOYWdu/cACQEEcc3RiVI6cF7MAAAAC//YAAAOxA4QABAA1AN4AsjMAACuwHTO0KgQAHwQrsiozCiuzQCovCSuwIi+0AgQAHwQrsAovsgAbHzMzM7QLBAArBCuwGTKwDi+0FQQAHwQrsg4VCiuzQA4SCSsBsDYvsAnWtAAFABsEK7IJAAors0AJCgkrsAAQsRIBK7QRBQAbBCuwERCxAwErtCEFABsEK7AwMrAhELEeASuwDDK0HQUAGwQrsBgysh0eCiuzQB0bCSuxNwErsQAJERKwJzmwEhGyByozOTk5sSEDERKxLS45ObAeEbEOFTk5ALEiKhESsAU5sAIRsAc5MDETFhczNQE2NyYnIzUhNCMiBgcjNDYzMhYdATMVIxEjESMVIyIOAgceATMyPgIyFRQGIyImjy17qf5NFZN3DloCzHw8MgdAU1BadK+vQKNfM0xjUBwTpEskPiEdDGQvdc4CQZwXs/58VFtnbkHFPjpMaWlzJkH9wAJA8wgZPi8hZh0jHQwnY28AAAD////5/2YC4wOBECIGgwAAEAMGaQLKAAD////5/vEC4wOBECIGgwAAEAMGagK8AAT////2AAACpwOhECIGggAAEAMGawKLAAD////5AAADaAPOECIGOgAAEAMGbANY//kAA//5AAAC3wO1AAgALwBAAKYAsiMAACu0PgQAHwQrsDkvsDMztAIEAB8EK7AuL7EAGDMztC8EACsEK7AWMrAQL7QLBAArBCsBsEEvsC3WsAkytAAFABsEK7AWMrItAAors0AtLgkrsAAQsTABK7QeBQAbBCuyHjAKK7NAHg0JK7NAHhgJK7FCASuxAC0RErAqObAwEbUCCxAcIzkkFzmwHhKwCDkAsTk+ERKxMB45ObACEbAcOTAxExQXMz4DNyUSITIVFAYjIg4DByEVIw4BBxYVFA4CIyIuBzUjNQE0JiMiDgMjHgMzMjZ9CXhKW0owGf4HEAFD312OPVo1JQ8HAmJpGk1GdREnTDU0Vz8yIRcMBwFEAgRZLQMKGStaPQ0nOVMyNkYCQIFRARAwTkNBATQxCwYeKkg4KkFYbyNEax02NCAbK0VDXUljPitB/iA4WwECAgEwT0coNQD////5AAADaAPVECIGOgAAEAMGbgMTAAAAAv/4AAACuQKBACUAOACPALIhAAArsAAvtCsEAB8EK7A2L7QGBAAfBCuwDC+wDzO0DQQAKwQrAbA5L7AD1rQmBQAbBCuwJhCxCwErtBAFABsEK7IQCwors0AQDwkrsgsQCiuzQAsMCSuxOgErsQsmERK0AAYZIy0kFzmwEBGzExscISQXOQCxNisRErQDGRwIIyQXObEMBhESsBM5MDE3IiY1NDYzMhc+ATchNSEVIxQOBgceBRcjJicOAScUHgIzMjcuByMiBt1QbnldY24ULQL97wLBcAMCBggPERoQBCEHFwsRCEMKQTOBsyAuJQ1qWgUjCh8OHRggETdIN3JTWGt5HpdFQUECIRgtJTMsMxYITRA6HjMbIq5VRMUnORsLmAUkCRwIEQYFSgAAAv/zAAACiAKBAAgAIwCQALIcAAArsB8vtAAEACsEK7AFL7QVBAAfBCuwES+wGTO0EgQAKwQrsBcyAbAkL7AJ1rQVBQAbBCuyCRUKK7NACREJK7AVELEEASuxFhwyMrQaBQAbBCuyGgQKK7NAGhkJK7ElASuxFQkRErEFBzk5sAQRsQAfOTkAsQAfERKwHTmwBRGwITmxERURErAJOTAxJTI2NzUhBgcWAzQuBCcjNTMyFSE1MxUjESM1BiMiJzc2ATMlVBT+8AopQEUDAwgDCgFpa1kBCciHQUJjm0wlH7MwFJNAWj0BMQ0YDhEHDwJBt7dB/cCuPHJiVgAAAv/5AAACygKBABYAHwCDALIRAAArsAsztBoEAB8EK7AeL7QDBAAfBCuwBi+xCQ0zM7QHBAArBCsBsCAvsADWtBcFABsEK7IAFwors0AABgkrsBcQsRwBK7AEMrQPBQAbBCuwDxCxDAErtAsFABsEK7ILDAors0ALCQkrsSEBK7EcFxESsBE5ALEeGhESsAA5MDE3NDY7ATUhNSEVIxEjESMRFCMiLgM3FBYzMjc1IyIgXUd1/sAC0YZAioQwTi4fCz9dOjkKVYXwRVuwQUH9wAJA/laWKTtGNRI6dzrXAAAB//kAAAL8AoEANQCsALIJAAArsAwvsBIztAAEACsEK7AkMrAbL7AGM7QcBAArBCuwBDIBsDYvsBjWtCAFABsEK7AgELEoASu0NAUAEQQrsxEoKw4rtDEFACQEK7A0ELEJASuwAzK0CAUAGwQrsggJCiuzQAgGCSuxNwErsSsgERKxEiQ5ObE0KBESsQ4uOTmxCTERErEADDk5ALEADBESsAo5sBsRtg4VICIoKzEkFzmwHBKwLjkwMSUyNjcRMxUjESM1BiMiJw4CIyImJz4BNTQnIzUzMhYVFAcWMzI+ATU0JjU0NjMyFhUUBhUUAdonKgfKiUEkMEVBGSAzGzpwCxE8PjJTGURISiYpNBEVKRUUHSGsGCABnUH9wI0iQhcZFWQjH7gnSwhBTkUuzkozQScrYwsnVFobEXoufQAAAAL/9wAAApsCgQAnADAApQCyIQAAK7AlL7QrBAAfBCuwLy+0BQQAHwQrsA8vtBYEAB8EK7ARL7AUM7QSBAArBCsBsDEvsA/WtBYFABsEK7IPFgors0APEQkrsA8QsAAg1hG0KAUAGwQrsBYQsQsBK7QcBQAbBCuwIDKyHAsKK7NAHBQJK7EyASuxCxYRErYFHiElKy0vJBc5ALEvKxEStQAeIygtCCQXObEPBRESsQscOTkwMTc0PgIzMhYXNzY1NCYjITUjNSEVIRUzMh4CFRQHFhcjJicGIyImNxQWMzI3JiMiPA4fPio+XDQrFUI6/uFNAqT96vcvRSIPXzYsRSIpWV5EXUA7Kkw7S0hZrxgrKRkyNjUbHy0itkFBdh4vLhZOTTFtSDRTTDgcKD9MAAAC//oAAAK8AoEAGAAhAJQAshEAACu0HgQAKwQrsBsvsBYztAYEACsEK7IGGwors0AGAwkrsAkvsAwztAoEACsEKwGwIi+wFta0GwUAGwQrsAUyshYbCiuzQBYACSuwGxCxGQErsAcytA4FABsEK7IOGQors0AODAkrshkOCiuzQBkJCSuxIwErsRsWERKxAxU5ObAZEbAROQCxBhsRErAAOTAxEzQ2MzIdASE1ITUhFSMRFAYjIi4CJyMiBTUhHgEzMj4BEUYzIwE8/hECwpJwWjFNRyoEOSMB2P7EA11PITsxAVMuPx421EFB/nNPZBk/ell+foRmETMAAAAD//gAAAKgAoEAJgAuADcA0wCyGwAAK7Q3BAArBCuwJzKwLy+wLjO0FAQAKwQrsA4vtAUEAB8EK7AIL7ALM7QJBAArBCsBsDgvsADWtBAFABsEK7AQELAzINYRtB8FABsEK7AfL7QzBQAbBCuyHzMKK7NAHwgJK7AQELE3ASu0JwUAGwQrsCcQsQYBK7QNBQAbBCuyDQYKK7NADQsJK7MrDQYIK7QXBQAbBCuxOQErsTMAERKwJTmxNxARErASObAnEbEbFDk5ALEvNxESsR8XOTmwFBGxEiU5ObAOErEAEDk5MDETND4CMyE1ITUhFSMVISIVFBc2MzIWFRQOASMiLgE1ND4DMyYFPgI1NCYnIw4CFRQeARc7GSQfCwE2/iACqIj+jy0bdCuZbyZ0bnJuLAkPDBABIgEWPEIsR2NAQ0IjLEE7AU0dLRUKikFByjQaPAgzRC8yHBUzNRIeFQwMQ9wBCBoZHxUCAggWFhkaCAEAAAAB//YAAAKdAoEAFgCIALITAAArsA4zsBEvsBQztAYEAB8EK7IGEQors0AGAwkrsAkvsAwztAoEACsEKwGwFy+wE9a0EgUAGwQrsAUyshMSCiuzQBMACSuwEhCxDwErsAcytA4FABsEK7IODwors0AODAkrsg8OCiuzQA8JCSuxGAErsRITERKwAzkAsQYRERKwADkwMRM0NjMyHQEhNSE1IRUjESMRIREjESMiGUU1IgEe/iMCp4pA/uJCNCYBOjVBHD/rQUH9wAEV/usBFQAAAv/5//4CggKBADwARQDqALIYAAArsBEvtCkEAB8EK7AdINYRtCIEAB4EK7AxL7AyM7RABAArBCuyMUAKK7NAMTUJK7A0MrAEL7EHPTMztAUEACsEKwGwRi+wLta0DgUAGwQrsg4uCiuzQA4HCSuxRwErsDYaug9vweQAFSsKsDQuDrAAELA0ELE7DPkFsAAQsTIM+boPmcHuABUrC7A0ELMzNDITK7IzNDIgiiCKIwYOERI5ALIAOzMuLi4BtAA7MjM0Li4uLi6wQBoBsQ4uERKwRTkAsREYERKxFhs5ObEiKRESsB85sDERsg4uODk5ObBAErALOTAxEy4BJyM1IRUjDgEHHgEVFAYjIicUFhUUIyImJyYjIjU0NjIeAjMyFjMyPgI1NCYjIg4BIyImNTQ2NzYnHgEzMj4CN8I7NB09AolxETg2OjtrYhcKMg0QOwsoSycnIBoQJhwFJQ0RKTMhVy0NZ1wBDiciJxUjKGwqIjslEwYBmR89S0FBQVQbFFcyT1ECAT8LDCYPOCwgGxYaFgEIEy0gM00ZGBwHCw8LBbFLQSE0JRIAAAAC//r//QKPAoEABQAyALAAsh8AACu0GgQAHwQrsBgvsCcztBUEAB8EK7APL7QDBAAfBCuwCS+xAAwzM7QKBAArBCsBsDMvsDHWtBIFABsEK7IxEgors0AxCQkrsBIQsQQBK7QOBQAbBCuyDgQKK7NADgwJK7E0ASuxEjERErEILDk5sAQRtQAGGBofJyQXObAOErMWFxwdJBc5ALEaHxESsB05sBgRsRwlOTmwFRKwLTmwDxGwMTmwAxKwBjkwMRMeATsBNQUmJyM1IRUjFSEiBhUUFjMhFSMWMzI3BwYjIiYnLgMnIi4HNTSmGlsgi/72SwtsApWJ/sMaPjIQAU/7K4YjIQs7KylYEhQUAxQZAQ8LFA4TDQwGAkA9O3h4N0FBQbckFx0sQJEKKRg3GR0wExAJBQQICw4SFhwQaAAAAAH/+f/9ApMCgQAfAGAAsgMAACu0GQQAHwQrshkDCiuzABkeCSuwCi+wDTO0CwQAKwQrAbAgL7AI1rQPBQAbBCuyDwgKK7NADw0JK7IIDwors0AICgkrsSEBK7EPCBESsBw5ALEKGRESsAY5MDElFAYjIiYnNiU1ITUhFSMVIg4EBx4BMzI+AjMyAhp6TT7gFGsBPP4xApqLJixTQU9LIymmLyM+IiEKCX8dZXVD5yGDQUHDAgoaKUcvM0waHhoAAAL/9v/+AqECgQANACkAgwCyDwAAK7QIBAAfBCuwGy+wHjO0HAQAKwQrAbAqL7AT1rQGBQAbBCuyEwYKK7NAExsJK7AGELEZASu0IAUAGwQrsCAQsQABK7QmBQAbBCuyJgAKK7NAJh4JK7ErASuxGQYRErAPObAgEbEDCDk5sAASsA45ALEbCBESsgMTJjk5OTAxJTQmIyIGBxQzMj4DBiIuAjU0PgM3NSE1IRUhFR4EFRQOAQIGd1dQdQLIMkssGwmcXFZUMwceL1s8/toCq/67PFovHQcyU9JQbmZYlRQeKSbAFC5ZPRMuRjkyCHBBQXAJMThGLhQ8WS4AAAL/+AAAAp0CgQAvADoApACyFwAAK7Q5BAArBCuwNC+0HQQAKwQrsCgvtAMEAB8EK7MdKCsOK7QABAAdBCuwBi+wCTO0BwQAKwQrAbA7L7Aa1rQ2BQAbBCuwNhCxJAErsAUytBEFABsEK7IRJAors0ARCQkrsTwBK7E2GhESsC05sCQRtgADFx0MKzAkFzmwERKwCjkAsTQ5ERKxGiI5ObAdEbERJDk5sQMoERKxDC05OTAxEzIWMzI3ITUhFSMGBx4DFRQOAyMiJjU0NjMyHgIXNjU0LgEjIgYjIjU0NgEuAiMiFRQWMzKXFVAYcFP+IQKlhS5WEicuHSk9VEknVWxLQRstQ0snIEJTLSpKF081ARgeKUsuWlFBOgHBFpVBQWhEBxkqQCU4VTAeCkI7Pz4HFTQoNSwwQRcTMRoe/p0eIBw0HiQAAAAC//f/+gKbAoEAIgAuALgAshwAACu0IwQAHwQrsCcvtBYEAB8EK7AQL7AgM7QHBAAfBCuyBxAKK7NABwQJK7AKL7ANM7QLBAArBCsBsC8vsCDWtBAFABsEK7AGMrIgEAors0AgAAkrsBAQsQgBK7QPBQAbBCuyDwgKK7NADw0JK7IIDwors0AICgkrsAgQsCUg1hG0GQUAGwQrsTABK7EQIBESsAQ5sAgRtBYcIycqJBc5ALEnIxESsRkUOTmxBxARErAAOTAxEzQ+ATMyHQEhNSE1IRUjFSEUHgEXNjMyFhUUBiMiJyYnIyIBMjU0IyIGBx4DFzc3FRcBJf4hAqSF/psGKCVFYUc8UD6RaDQCOh8BfVlLIjMjDCQNGwF1KDcQD0GsQUHsITFYLW1MMzc6kkt9/uQ5QCgsBhQGBQAAAAH/+QAAApsCgQAuAJUAsioAACu0IQQAHwQrsiEqCiuzACEkCSuwHC+0AgQAHwQrsxUCHAgrtBQEAB8EK7ANL7AQM7QOBAArBCsBsC8vsATWtBcFABsEK7IXBAors0AXFAkrs0AXEAkrsgQXCiuzQAQNCSuxMAErsRcEERKwGTkAsRwhERKxABg5ObAVEbAEObEUAhESsQUXOTmwDRGwBzkwMTc2MzIXNS4FJyM1IRUhHgEXFSYnFSMuASMiBx4BMzI2MzIVFA4BIyIuAiZagDw7DUkWMxcfDJ0Cov5RH+BFRzIPJGkhSEcciVUcsgwKQm4wIFBpV7TWMFcGIAsbEx4SQUEjVw08DBTIQDWWKlA3BQwzLQ4iTgAB//oAAwKRAoEAKgCFALALL7QSBAAfBCuyEgsKK7MAEhAJK7AYL7QiBAAfBCuzHhgbDiu0HwQAHgQrsCcvsAAztCgEACsEKwGwKy+wFdawJDK0BQUAGwQrsAAysgUVCiuzQAUqCSuyFQUKK7NAFScJK7MAFQ8JK7EsASsAsRsSERKxBRU5ObEiGBESsQMdOTkwMQEOAQcWFRQOAyMiLgE0MhYzMjY1NCYjIgYjIjU0MzIWMzI3NjUhNSEVAhoKNjl4GCQyLxk2lWYou0hAO21aKkwITT8dbCKAKQH+IAKXAkBNcS4/ZSg+JRkJLjUYPz0+OEIONS8bzAMCQUEAAAAAA//6AAACigKBABAAFwAiARIAsgwAACuwDy+0GAQAKwQrsBwvtBUEAB8EK7AGL7EJETMztAcEACsEKwGwIy+wA9awAjK0EwUAGwQrsAUg1hG0EQUAGwQrsBUysgURCiuzQAUGCSuwExCxDAErsRYaMjK0CwUAGwQrsgsMCiuzQAsJCSuxJAErsDYauj388BIAFSsKBLACLg6wAMAFsRwX+Q6wIcCwABCzAQACEyuwIRCzHSEcEyuzHiEcEyuzHyEcEyuzICEcEyuyAQACIIogiiMGDhESObIfIRwREjmwIDmwHjmwHTkAtwAhAQIdHh8gLi4uLi4uLi4BtwAcIQEdHh8gLi4uLi4uLi6wQBoBsQwTERKxDxg5OQCxGA8RErANOTAxNz4BNTQnIzUhFSMRIzUGIyIDFhUUByE1AzI3NSEOAwcWMBElDGACkIhBWGViCA0HASGySmj+1AgLBAQCPtEssSgsPkFB/cCOPQHvRyEWLqz+Uj2FHiwRDghRAAAAAf/4AAACpQKBACIAnACyGwAAK7QSBAAfBCuyEhsKK7MAEhUJK7APL7AgM7QGBAAfBCuyBg8KK7NABgMJK7AJL7AMM7QKBAArBCsBsCMvsCDWtA8FABsEK7AFMrIgDwors0AgAAkrsA8QsQcBK7QOBQAbBCuyDgcKK7NADgwJK7IHDgors0AHCQkrsSQBK7EPIBESsAM5sAcRsRIbOTkAsQYPERKwADkwMRM0NjMyHQEhNSE1IRUjESEUFjMyNjMyFRQOASMiLgI1IyIfWysWASP+GgKth/6eU2kofggJKVo1SWQ2F0gWAT41UhZK20FB/uVvejAGDS4rKlFkRQAAAAL/9gAAAogCgQAQABsAigCyDAAAK7APL7QYBAArBCuwBi+xCREzM7QHBAArBCsBsBwvsAXWtBEFABsEK7IFEQors0AFBgkrsAUQsAMg1hG0EwUAGwQrsBEQsQwBK7AaMrQLBQAbBCuyCwwKK7NACwkJK7EdASuxEQMRErAWObEMExESsQ8YOTkAsRgPERKwDTmwBhGwADkwMTc+ATU0JyM1IRUjESM1BiMiAxYVFAYHFjMyNxEwGhwJZwKSjEBZX2IFCRYYPllFaOhCjC0rMkFB/cCkPQHZMy41ZktRPAFcAAAAAAH/9P/+AoMCgQApAKQAsgcAACuwIzOwAC+0DwQAHwQrsBYysBEvsBQztBIEACsEKwGwKi+wDNa0AwUAGwQrsgMMCiuzQAMHCSuyDAMKK7NADBEJK7ADELEPASu0FgUAGwQrsBYQsScBK7QZBQAbBCuyGScKK7NAGRQJK7InGQors0AnIwkrsSsBK7EWDxESsAA5sCcRsB85sBkSsB45ALEABxESsQwZOTmwDxGwFzkwMQEiBhUUFhcVLgM1NDY3NSE1IRUhFR4BFRQOBwc1PgE1NCYBJkF5ITMlLC4ViVD+7wKP/sNSiAYPDRkOHgweAjMgdwFtXUgxPRtBERouQi9bfweXQUGXB4FZGSsiGhgOEAYNAUEbPTFIXQAAAf/3AAACmgKBACMAdACyDQAAK7AQL7QCBAAfBCuwHC+wCjO0HQQAKwQrsAgyAbAkL7AY1rQhBQAbBCuyGCEKK7NAGBUJK7AhELENASuwBzK0DAUAGwQrsgwNCiuzQAwKCSuxJQErsQ0hERKxAhA5OQCxHAIRErQHAA4YISQXOTAxNxYzMj4CNxEzFSMRIzUGIyIuAjU0NjU0JisBNTMyFhUUBnZPVxw3NRQVzY1ATGIoWEApTCUqPGItPi3zSA4cDQ8BkEH9wLBFHigoCw7LICc8QWc2LJIAAv/4AAACnQKBACcAMQCaALIAAAArtC8EAB8EK7AqL7QiBAAfBCuwEy+0CgQAKwQrsA0vsBAztA4EACsEKwGwMi+wBNa0FgUAGwQrsgQWCiuzQAQNCSuwFhCxCwErtBIFABsEK7ISCwors0ASEAkrsAsQsCgg1hG0JQUAGwQrsTMBK7ELFhEStAoAIiotJBc5ALEqLxESshslHDk5ObETIhESsQQWOTkwMSEiLgE1ND4DNyE1ITUhFSMVISIGFRQeAxc+BDMyFhUUBjc0IyIGBxYXMjYBd0WWbBkcMRMRARv+IwKlif7PQjIFEgglBwwPKilBJD9UYSFXK1ocUT45ME2NTyU7HxkGBXRBQbU+JhAZIQ4xChARJhYSRzg7SYJCMSkrAioAAAAD//cAAAJ9AoEAGwAhACoAZACyAQAAK7AFL7QiBAArBCuwJy+0HwQAHwQrsBcvsRocMzO0GAQAKwQrAbArL7AB1rEgJTIytAAFABsEK7IAAQors0AAGgkrsSwBKwCxJyIRErEJAjk5sB8RsA45sBcSsBA5MDEhIzUOASMiLgEnPgM3LgYnIzUhFSMhHgEXMzUDMjY3NSMGBxYB90EQeiYdUV4SDSU1Hx4BIQ4fEhcQBEkChob+ihE/PqenMG0KsjlfVnYWMxdFMxsyLxkWARsNHx0oMRtBQT9TLb/+LjsXgRpvSgAC//cAAAJ6AoEALgA4ALkAsgAAACu0CgQAHwQrsgoACiuzAAoGCSuwEy+0MgQAKwQrsDcvtB0EAB8EK7AiL7AlM7QjBAArBCsBsDkvsBjWtC8FABsEK7AvELEPASu0LAUAGwQrsCwQsCYg1hG0IQUAGwQrsCEvtCYFABsEK7ImIQors0AmJQkrsiEmCiuzQCEiCSuxOgErsS8YERKxBgQ5ObAPEbUIEx0fKDUkFzkAsRMKERKxDyw5ObE3MhESsxgfKBEkFzkwMSEiLgE1NDMyHgEzMj4CNTQnBiMiLgI1ND4CMzIXNjUhNSEVIxQHHgIVFAYBFBYzMjY3JiMiARgqcFATDzZgQSg7GwstaGkpOxsMDyRLNF5IS/4tAoNwXhsXFnn+7CEpMUksPUlqHSsRDxQUITEnDz0qYR0tJxIXKywaSlBhQUGDXR8eOiFXcQFPHyEmKDwAAAH/+QAAAqECgQAdAIcAshcAACuwGS+0EAQAHwQrshkQCiuzQBkcCSuwCS+wFDO0CgQAKwQrsBIyAbAeL7AF1rQNBQAbBCuyBQ0KK7NABQAJK7NABQkJK7ANELERASuwFzK0FQUAGwQrshURCiuzQBUUCSuxHwErsQ0FERKwGTkAsRkXERKwAzmxCRARErEFDTk5MDE3ND4CNTQmKwE1MzIVFAYVIREzFSMRIxEhDgEjIisdIh0VHltnaQMBEcqKQP7pESYpNVkaRD9vP1dFQc8QQggBKUH9wAEZg3YAAAAAAv/6AAAC7QKBABYAIgCXALIJAAArsBEvtBwEAB8EK7ALL7QfBAAfBCuwAy+xBiEzM7QEBAArBCsBsCMvsADWtBcFABsEK7IAFwors0AAAwkrsBcQsR4BK7QMBQAbBCuwDBCxCQErsCAytAgFABsEK7IICQors0AIBgkrsSQBK7EXABESsRkiOTmwHhGxERw5OQCxCxwRErEUGTk5sQMfERKwADkwMRM0JyM1IRUjESMRIxUUDgIjIiYnNzY3FAceATMyPQEzNSFmDGAC84c/lRcnJxREmBUXJ0A5HWcrNdb+cwHkClJBQf3AAR1pJDUbDG0qT3xMcZMjS1+O4wAAAAL/+v//AngCgQAQABsAcACyAAAAK7QRBAAfBCuwFi+0BgQAKwQrsAkvsAwztAoEACsEKwGwHC+wBNa0GAUAGwQrsgQYCiuzQAQJCSuwGBCxFAErsAcytA4FABsEK7IOFAors0AODAkrsR0BK7EUGBESsAA5ALEWERESsAQ5MDEFIi4BNTQ7ATUhNSEVIxEUBicyNj0BIyIVFBcWAXQ7kWWC7f5IAn6FSzcdJOZMWl0BaZc9bJhBQf5lWU0/MCbTKD1iYgAC//b//AKzAoAAJgAqAI4AshMAACuwJjO0EgQAHwQrsAAysBsvsR4oMzO0HAQAKwQrAbArL7AW1rQMBQAbBCuyDBYKK7NADBMJK7IWDAors0AWHAkrsAwQsQMBK7QjBQAbBCuyIwMKK7NAIx0JK7IDIwors0ADJgkrsSwBK7EDDBEStRkaHyAoKSQXOQCxGxIRErQGFiMnKiQXOTAxJTI2NTQmIwcjJyIGFRQeAzMVIiY1NDY3JyM1IRUjBx4BFRQGIwMTIRcBqUJaUz5dCFw/VBslLyEMXH1pSU6RAr2TTUdqfF9RfP8AezpbQUdZq6teQiU7IBUHPn1dW3AMkkFBkgxxWliCAUUA//8AA//r//MC3gKBAAoAMQA1AMIAsh4AACuwMTO0HQQAHwQrsAsysgMAACu0CQQAHQQrsCYvsSkzMzO0JwQAKwQrAbA2L7Ah1rQXBQAbBCuyFyEKK7NAFx4JK7IhFwors0AhJgkrswAXIQgrsQYF6bAGL7EABemwFxCxDgErtC4FABsEK7IuDgors0AuKQkrsg4uCiuzQA4xCSuxNwErsSEGERKxAwk5ObEOFxEStSQlKiszNCQXOQCxHR4RErEABjk5sSYJERK3DhESFBchLjIkFzkwMTcUBiMiJjU0NjMyBTI2NTQmIwcjJyIGFRQeAzMVIiY1NDY3JyM1IRUjBx4BFRQGIwMTIRdSHRYXHRkbMwGCQlpUPlwIXD9UGyUvIQxcfmpITboC5pNOSGp8X1F7/wB8KhYhHRYPJiBbQUZaq6teQiU7IBUHPn5cWnEMkkFBkgtzWViCAUQA//8AAf/5//0CggKBACsApQCyHAAAK7QXBAAfBCuwEi+0DwQAHwQrsAkvtAAEAB8EK7ADL7AGM7QEBAArBCsBsCwvsCfWtA0FABsEK7INJwors0ANEAkrsicNCiuzQCcDCSuwDRCxAQErtAgFABsEK7IIAQors0AIBgkrsS0BK7EBDRESsxIXHCQkFzmwCBGxGRo5OQCxFxwRErAaObASEbIZISI5OTmwDxKwJDmwCRGwJzkwMRMhNSE1IRUjFSEiDgEUFjMhFSMeAzMyNwcGIyIuAicuBDU0PgKtAQ3+PwKJif68DiQnKxcBTvoJKzYlER44DTsqKUgvHQcEIispHA4ePQHIeEFBtwcdLjBALj0ZCAsxGCo/NRYKEhIbNCUNIykcAAAAAAP/+QAAAqoCgQAUABkAJQCyALIMAAArsCMg1hG0HQQAHQQrsA4vtBcEACsEK7IOFwors0AOEgkrsAYvsQkVMzO0BwQAKwQrAbAmL7AE1rQXBQAbBCuyBBcKK7NABAYJK7AXELEaASu0IAUAOgQrsCAQsQwBK7AYMrQLBQAbBCuyCwwKK7NACwkJK7EnASuxFwQRErIOEBU5OTmxIBoRErEdIzk5ALEdIxESsRAAOTmwDhGwAjmwFxKwAzmwBhGwBDkwMTc0PgE0JyM1IRUjESMRIQ4CIyImExYVITUDNDYzMhYVFAYjIiYzLy4kcwKxiUH+8QocIB4RKXokAQ/aIRgVGh4YGBpaGl13cIhBQf3AARUek0UcAgV0dur+ABgeIRUWHh8AAAAAAv/5AAACqgKBABQAGQCGALIMAAArsA4vtBcEACsEK7IOFwors0AOEgkrsAYvsQkVMzO0BwQAKwQrAbAaL7AE1rQXBQAbBCuyBBcKK7NABAYJK7AXELEMASuwGDK0CwUAGwQrsgsMCiuzQAsJCSuxGwErsRcEERKyDhAVOTk5ALEODBESsAI5sBcRsAM5sAYSsAQ5MDE3ND4BNCcjNSEVIxEjESEOAiMiJhMWFSE1My8uJHMCsYlB/vEKHCAeESl6JAEPWhpdd3CIQUH9wAEVHpNFHAIFdHbqAAAAAAH/9gAAAnQCgQAgAHgAshMAACu0BQQAHwQrsB8vtBwEAB8EK7AJL7AMM7QKBAArBCsBsCEvsBfWtAAFABsEK7IAFwors0AAHQkrsAAQsQcBK7QOBQAbBCuyDgcKK7NADgwJK7IHDgors0AHCQkrsSIBK7EHABESsBM5ALEfBRESsBc5MDETFB4CMzI1ESE1IRUjERQOAiMiLgE1ND4COwEVIyJ2ITZVLl3+SQJ+iB0wMRo7hV4NGzckMShMARIUREczYAGgQUH+Yy5EIg9MhEYNIyocQAAAAAH/Xf9k/8f/zgALACoAsAcvtAEEAB0EK7QBBAAdBCsBsAwvsArWtAMFADAEK7QDBQAwBCsAMDEGMhYVFA4BIyImNTR9HiYHGhQbGjIaHAgVFyUPHAAAAAAB//MA+gE1AoEABwBEALADL7AGM7QEBAArBCuyAwQKK7NAAwEJKwGwCC+wAda0AAUAGwQrsgABCiuzQAAGCSuyAQAKK7NAAQMJK7EJASsAMDE3IxEjNSEVI5dAZAFCnvoBRkFBAAAAAAH/+wAAAegDpQAYAGoAsgsAACuwDS+wCDO0DgQAKwQrsAYysAAvsAMvtBMEAB8EKwGwGS+wC9awDzK0CgUAGwQrsAYysgoLCiuzQAoICSuyCwoKK7NACw0JK7AKELEAASu0GAUAGwQrsRoBK7EAChESsBM5ADAxAS4BIyIGFTMVIxEjESM1MzU0NjMyHgIVAakFOThHNJycQH19a2MbNDMgAuJMOl+IQf3AAkBBOoNnEypQNgAAAAAB/yIAAAFCA4QAFgBqALIJAAArsAsvsAYztAwEACsEK7AEMrAUL7AQL7QABAAfBCsBsBcvsBTWtBMFABsEK7ATELEJASuwDTK0CAUAGwQrsAMysggJCiuzQAgGCSuyCQgKK7NACQsJK7EYASuxCRMRErAAOQAwMQMyFh0BMxUjESMRIzUzNCYjIgYHIzQ2O15wr69AXFw8QDc4BkBQA4RhaDpB/cACQEF1USs6RlwAAAH9+v9m/2j/zwASAB4AsAsvtBAEACsEKwGwEy8AsRALERKyCQ0AOTk5MDEHMA4IIyInNRYzMjeYGAUYCRgPGBQZDFlfY1VYXnIJAggDBwIFAgIoQSgnAAAC/fr+7f9o/8oAEgAeADgAsBUvtBwEAB8EK7ALL7QQBAArBCsBsB8vALEcFRESsRkTOTmwCxGxGh45ObAQErIJDQA5OTkwMQcwDggjIic1FjMyNxUGIyIuASc1FjMyN5gYBRgJGA8YFBkMWV9jVVheaVkkRyUcY1VYXncJAggDBwIFAgIoQSgntScODQxBKCcAAAAAAf4KAov/egOhABIAIgCwDy+xAATpsg8ACiuzAA8HCSsBsBMvALEADxESsBE5MDEBMhYXFhUUIyIuAycmIyI1NP43PX0haAMDEh4mPSE0WigDoUomeCkEFCQqMxUhIycAAv3fApD/fAPVAAEAKAAsALAQL7QWBAAfBCuwJy+0BQQAKwQrAbApLwCxFhARErATObEFJxESsAA5MDEBAAE0NjMyHgMVFAcuASMiJjU0MzIeBxcuBiMi/jcByf3qKyM0aEw9HwGKXWomJVQUKiklKB0iEhkCBykSKCIyOyNNA6H8XwOsExY6VFxIDwMBUB4LESYHDg8WERgMFAELQBkyFxwLAAAB/iECpv9tA6sAGwBBALAKL7QYBAAfBCuyChgKK7MACgIJK7IYCgors0AYEQkrAbAcL7AP1rQUBQARBCuwFBCxAAErsQAUERKwCjkAMDEDFCIuATEmIyIGIyIuAjU0MzIWFx4CHwEeAZMLFREMLQRVDBwkKRQECQ4BAxYbGoYxKwK9FisvDwEFEy0jNCANFxgFAQMCOQAAAAH9zwLH/4kD1QApAFcAsA0vtBgEABMEK7INGAors0ANBQkrsA0QsCcg1hG0GwQAHwQrshsnCiuzQBsSCSsBsCovsArWtAAFABEEK7IACgors0AAAwkrsgoACiuzQAoQCSsAMDEBFBYVBiMiLgI1NCYjIiY1NDcyHgEXFjMyNjMyFhUUBiMiJzY3JiMiBv7FEQIDBhEWDhsdMl0IAwwOBSRJL2EbM0UmEgMCDgYMQyErAxETMgIDCBMrHw8LNS8pAhkfBR0bPzQmNQMkJkssAAAB/q7+4//F/8wADAAcALAAL7QBBAAfBCsBsA0vsADWtAoFAAgEKwAwMQU1Mx4GFwcm/q4LIz8xJiMTGgMcaWw4AhQjIDEdMAYMsQAAAf6u/uP/xf/MAAwAHACwAi+0AAQAHwQrAbANL7AK1rQABQAIBCsAMDEHFSMuBic3FjsLIz8xJiMTGgMcaeU4AhQjIDEdMAYMsQAAAAP/8wAAAosCgQAJACQALgC8ALIbAAArsCgg1hG0LQQAHgQrsB8vtAAEACsEK7AFL7QUBAAfBCuwDy+wGDO0EAQAKwQrsBYyAbAvL7AK1rQUBQAbBCuyChQKK7NACg8JK7MlFAoIK7EqBemwKi+xJQXpsBQQsQQBK7EVGzIytBkFABsEK7IZBAors0AZGAkrsTABK7EKKhESsw4iKC0kFzmwJRGwBzmwFBKwBTmwBBGxAB85OQCxAB8RErAcObAFEbAiObEPFBESsAo5MDElMjY3NSEGBx4BAzQuAScjNTMyFhUhNTMVIxEjNQ4BIyImJzc2ExQGIyI1NDYzMgEzJVwO/ugIKhxxkAoFCmlrMCcBDcmIQRxZIj2YIiAhFRsXMxwXMsoZDZovXhsYARoZKQkRQVtct0H9wK4TEzMzWFv+qBYfMBgeAAAD//r/9AMJAoEACwAhACoAngCyHQAAK7AXM7QlBAAfBCuyAwAAK7QJBAAdBCuwKS+0DwQAHwQrsBIvsRUZMzO0EwQAKwQrAbArL7AG1rASMrEABemwABCxDAsrtCIFABsEK7AiELEnASuwEDK0GwUAGwQrsBsQsRgBK7QXBQAbBCuyFxgKK7NAFxUJK7EsASuxJyIRErAdOQCxJR0RErEABjk5sSkJERKxDCI5OTAxNxQGIyImNTQ2MzIWNzQ2OwE1ITUhFSMRIxEjERQjIi4CNxQWMzI3NSMiXxsWFx0dFxUcAlxIdv5/Aw+JQIWDPFosFT9cPDcMVoUrFyAdFhUgHLBDXbBBQf3AAkD+VpY8VUgYOXg61wAAAv/2AAACmwKBAAsAIgCiALIfAAArsBozsAMg1hG0CQQAHQQrsB0vsCAztBIEAB8EK7ISHQors0ASDwkrsBUvsBgztBYEACsEKwGwIy+wH9a0HgUAGwQrsBEysh8eCiuzQB8MCSuwHhCxBgErtAAFADAEK7AAELEbASuwEzK0GgUAGwQrshobCiuzQBoYCSuyGxoKK7NAGxUJK7EkASuxHh8RErAPOQCxEh0RErAMOTAxJRQGIyImNTQ2MzIWJTQ2MzIdASE1ITUhFSMRIxEhESMRIyIBcB4YFx0dFhUi/qlFNSIBHv4jAqWIQP7iQjQmQhYgHxUXHhjdNUEcP+tBQf3AARX+6wEVAAAAAAH/+v/9Ap0CgQA6AIYAsgUAACuwDzOwCS+0GQQAHwQrsCEvsSYE6bMpJiEIK7QeBAArBCuwMC+wMzO0MQQAKwQrAbA7L7Ac1rQ5BQAbBCuyORwKK7NAOTMJK7E8ASuxORwRErAvOQCxCQURErEDDTk5sBkRswcACAskFzmwIRKzEhUcOSQXObEpHhESsSM2OTkwMSUeARUUIyImJwciJxYVFCMiJjU0NjMyHgEzMjY1NCMiBiMiNTQ2MzIWMzI+AzchNSEVIwYHHgEVFAGSATwPEF4FVEE4LA4ZaA8IEDxjP1BmhTFuDmg5OCFnCxw1JB8QBP4QAqN0D2MfQVgCOBARSwIFG0EPEZAZDA0eHks3Vw0tFBoNGycwIg1BQWFRCkY2dgAD//r/9gKgAoEADAAsADYAzgCyKQAAK7Q0BAAfBCuyBgAAK7QABAAdBCuwLy+0IwQAHwQrsBgvtA8EACsEK7ASL7AVM7QTBAArBCsBsDcvsA3WtBsFABsEK7AbELADINYRtAoFADAEK7AKL7ASM7QDBQAwBCuwGxCxEAErtBcFABsEK7IXEAors0AXFQkrsBAQsC0g1hG0JgUAGwQrsTgBK7ENChESsQAGOTmxEBsRErUPIykvMjQkFzkAsTQpERKxCgM5ObEvABEStCAhJi0yJBc5sRgjERKxDRs5OTAxNzIWFRQGIyIuATU0Njc0NyE1ITUhFSMVISIGFRQeAxc2MzIWFRQGIyIuAQU0IyIGBxYzMjYwFh0aGwgVFyYTigEb/iMCpYn+zz81BRIIJQdYe0BUYkhElm0BsVgsWRtSPTA5XiAVDyQHGhQbGMt9JnRBQbU8KBAZIQ4xCm9INztJTY1YQjIoLSYAAAAAAgAhACgCagJxAAoAFgBMALALL7QDBAAfBCuwCC+0EQQAHwQrAbAXL7AO1rQABQAbBCuwABCxBQErtBQFABsEK7EYASuxBQARErELETk5ALEIAxESsQ4UOTkwMRMUFjI2NTQmIyIGEyImNTQ2MzIWFRQGYYTAhYVgX4Xkeqqpe3ypqQFMX4WEYGGEhf58pX98qax5e6kAAAACAB//yQITAqsAIgAxAH0AsB0vtCsEAB8EK7IdKwors0AdFgkrsCMvtAYEAB8EKwGwMi+wANa0JgUAGwQrsCYQsTABK7AbMrQJBQAbBCuyCTAKK7MACRQJK7AwELAZINYRtAwFABsEK7EzASuxGSYRErMGHSMrJBc5ALErHRESsBs5sCMRsQkAOTkwMRM0PgMzMhYVFAYVFB4DFxYVFCMiJjU0NwYjIi4DNyIGFRQeAjMyPgI1NB8KHzBXOGVoEQoVDx0DAgk4TQ41dy1JKx0K3UZXIzQpDxIyOScB9hgsMyUZZV0n3BcpRTgfLwYDBAWzYVJiPxsoMCSCPzIfLhQICxYsHXAAAAABABUAAwIrAp4AIwBlALAQL7QUBAASBCuwHy+0AwQAHwQrsh8DCiuzAB8iCSsBsCQvsBLWsAAytAkFAAcEK7AJELEdASu0BQUAGwQrsSUBK7EJEhESswMHFx8kFzkAsRQQERKxBxc5ObAfEbEFHTk5MDETNDYzIBUUBRYVFCMiLgEvASY1NDMyFjMyPgM1NCMiBiMiGIxpAR7+9Z8XDUNeIYY+Ow9oHxc8Sz0q7j9/Ch0CWh4m9N5ETCUUIi8LEQ4hQSQNIzNXNbMhAAABABUAAQIuAp0AQACaALA9L7AJL7EOBOmzEQ4JCCu0BgQAHwQrsBYvtB0EACsEK7IWHQorswAWGQkrAbBBL7AD1rQqBQAbBCuwKhCwICDWEbQTBQAbBCuwEy+0IAUAGwQrshMgCiuzABMbCSuxQgErsRMDERKwMzmwKhGyIycxOTk5ALEJPRESsQMqOTmwBhGwJzmwERKxCyM5ObEWDhESsRMgOTkwMSUyNjU0JiMiBiMiNTQ2MzIWMzI1NCYjIgYjIjU0ITIWFRQOAhUeAxUUBxYfARYVFCMiLwEuAzU0MzIeAQEmOYY+MhCdIV5IKhxsH4t7XB62CCUBCHSdFx0XARcYFLwUFDQ7HRE3WzV+SDI9H0RKjVAxKzIUKRoXEFstMxocP1lJHi4VEwYFFRYsGnQ5CgQRFxIVDyQYHwohHyopKQACABT//wIAApIAKwA1AMQAshoAACu0NAQAKwQrsC8vtAMEAB8EK7AqL7AIM7QpBAAfBCuwCTIBsDYvsCfWtAAFABsEK7IAJwors0AAKgkrsCcQsB4g1hG0MgUAGwQrsAAQsQYBK7QLBQAbBCuyBgsKK7NABggJK7AGELAsINYRtBUFABsEK7E3ASuxAB4RErAlObAyEbAhObAsErUDEBkaIiMkFzmxFQYRErEOEzk5ALEvNBESshMeFTk5ObADEbIQISM5OTmwKhKzCw4lJyQXOTAxExQWMzI2NTQnNRYVFA4CFRQeAhUUDgIiLgI1ND4CNC4CNTQ3FQYBNCYjIgYVFDMyU1pdYFVqqxwiHBQZFStHR0pHRywVGBUcIRypagFVTlBRTp+eAdk1Wlg3Wh9AIpMlPyAhCwgVFjUlLkMhDw8hQy4jMxYWFCAiQCWTIkAf/m08Li48YAAAAAABAAAAAAHyAoEAHQBrALILAAArsA4vtAUEAB8EK7AZL7QaBAArBCuwCDIBsB4vsBXWtAAFABsEK7IVAAors0AVEgkrs0AVGgkrsAAQsQsBK7AHMrQKBQAbBCuxHwErsQsAERKxBQ45OQCxGQURErMABwwSJBc5MDETFAYHFjMyNxEzESM1BiMiLgE1NDY1NCYrATUzMhaoKiRXT01lQEBMYzduQ0wlKhg9LzwB5CiROEhGAZD9f7BFJjkaFMYfJzxBZwAAAQAQAAAB5gM9AEgAywCyIAAAK7QZBAAfBCuwES+xDATpsxQMEQgrtAkEAB8EK7ADL7QuBAAfBCuyAy4KK7NAAwAJK7A9L7Q1BAATBCuwOiDWEQGwSS+wI9awKzK0FwUAGwQrsAYysBcQsTIBK7RABQAbBCuyQDIKK7NAQBwJK7BFMrFKASuxFyMRErAnObAyEbMDCRQuJBc5sEASsDA5ALERGRESsRcjOTmxCRQRErEPJzk5sQMMERKxBis5ObAuEbIwQ0U5OTmwOhKxMkA5ObA9EbA4OTAxASImIyIGFRQWMzI2MzIWFRQjIiYjIgYVFDsBMhUUBisBIiY1ND4BNSYnJjU0NjMyFyY1NDYzMhYVFCMiJiMiBhUUHgIVFA4BAY8FeTxFPkg7DF0OIzxgGVYHSjlwyTEQIelBTx0dNQQDbVklNDdDSBhLDglACiAtKC8oBRQB/iI9JDdAEBMTMApHL1YiFApeRiM3IglxFQ0QQk8KRCBEQhoSCQopHSQ8Hx8LBg4RAAABAA4AAAJHApgALABLALIQAAArsB4vtAAEAB8EK7IeAAorswAeKAkrAbAtL7Ab1rQDBQAbBCuyGwMKK7MAGxIJK7MAGyoJK7EuASsAsR4QERKxAxs5OTAxATIWFRQOCAcGIyI1ND8BPgQ1NCYjIg4BDwEOAyMiNTQ2AVFpjQoWFyoiOShFKiZ1OBI6RmiWSyoIa0odNjYMBAQDCQwHLIsCl3pfITs0LCohJBgiFBE0Bw8bHS1eR04tHENgDisiCwwGDwUzPVkAAAEADgAAAlgCggAiAG8AshgAACu0EQQAHwQrsAkvsCAztAYEAB8EK7IGCQors0AGAwkrAbAjL7Ae1rQLBQAbBCuwBTKyCx4KK7NACwgJK7IeCwors0AeAAkrsSQBK7ELHhESsAM5ALERGBESsBY5sAkRsB45sAYSsAA5MDETNDYzMh0BIRUhBhUUHgMzMjYzMhUUIyIuAzU0NyMiDlYqFwGz/k0BDy1Jf1MFJQMvazRkbVE0A0AXAfwyVBdHQAYiNmBqSzEDICMWPV2cYyAVAAABAA4AAAJqAxUANwCmALIvAAArtCgEAB8EK7AjL7A1M7QGBAAfBCuyBiMKK7NABgMJK7AXL7QPBAATBCuyFw8KK7MAFxQJKwGwOC+wNda0IwUAGwQrsAUysjUjCiuzQDUACSuwIxCxDAErtBoFABsEK7IaDAors0AaIAkrswAaEgkrsTkBK7EjNRESsAM5sRoMERKwBzkAsSgvERKwLTmxBiMRErEAHjk5sBcRsQwaOTkwMRM0NjMyHQEhJicuATU0NjMyFhUUIyImIyIGFRQeARcWFRQjIRQeAjMyNjMyFRQjIi4DNSMiDlYqFwEMAwUbE0BLHUcPCUAKIS0OLiMeYP7OI0uJXwUlAy9rY5JSMQ9AFwH8MlQXRwQHJSkgMEgeDgoKKB0QKjcRDRgZWpB4QgMgIz5eiXdIAAAAAf7RAsP/6AOjABoAWgCwFS+wBjOwDi+0AAQAEwQrAbAbL7AY1rQQBQARBCuyEBgKK7MAEBMJK7AQELELASu0AwUAEQQrsgsDCiuzAAsICSuxCxARErEADTk5ALEOFRESsQMYOTkwMQMyFhUUBiMiNTQ2NTQmIgYVFBYVFCMiJjU0NqRCSjARBB89Uj0gBQ8xTQOjQjUgSQMHQxUhLjEjEz8IA0kgNUIAAf6cAsP/4AOBABAAQgCyAwIAK7QMBAAfBCuyDAMKK7NADAYJK7AAMgGwES+wBta0BwUAEQQrsAcQsRABK7QABQARBCuxEAcRErADOQAwMQMOASMiJjUzHgMyPgI3IAFZSElZHAIMGzhKNxwLAwOBVWlsUg8kMSAgNB8RAAL/9gAAAqcCgQAhACYAlQCyHwAAK7QWBAAfBCuyFh8KK7MAFhsJK7ALL7QkBAAfBCuwBS+xCCIzM7QGBAArBCsBsCcvsATWtCIFABsEK7IEIgors0AEBQkrsCIQsSUBK7QKBQAbBCuwHDKyCiUKK7NACggJK7EoASuxIgQRErATObAlEbIWHwI5OTmwChKxGRo5OQCxCxYRErAAObAkEbACOTAxNzY3JicjNSEVIxUjIg4FBx4BMzI+AjIVFAYjIiYTFhczNS4VkncOWgKxiGcFEzc1Rjs4EROrTCQ+IR0MYTBu1kQte6m7VlpnbkFB8wEHCxYdLhwgZR0jHQwnYm8B0ZwXswAAAAT/+QAAAuMDgQAIACkALwA7ALcAsiEAACu0OQQAHwQrsDcvsDMztCsEAB8EK7AoL7EWKjMztCkEACsEK7EAFDIysAMvtA4EAB8EKwGwPC+wJ9awCTK0KgUAGwQrsAgysicqCiuzQCcoCSuwJxC0KwUAGwQrsCoQsTABK7QcBQAbBCuzABwwCCuwLzO0FAUAGwQrshQACiuzQBQWCSuxPQErsSonERKwIzmxMCsRErQOAyEaNyQXOQCxNzkRErEwHDk5sCsRsBo5MDEBNCYjIg4CFSM0PgIzMh4DFTMVIw4BBxYVFA4CIyImLwE0NyM1HwEzMjY3AzQmIwcOASMWMzI2AkBzZjxaMRhAGzx3UjxiPioSY2IcTEV0ESdMNI6mDwYBT48Ieox5MjlaLA4Oa2FBsTZGAoFMdCM5QSMtU1AwITRERSJBWm4iRGscNjUg0LKGJBRBQdJRgf5iN1sCAQPuNQAABQAM/8kF7gPYAE4AZgByAHgAgwF8ALI6AAArtIIEACsEK7B9L7B/M7R1BAAfBCuwWyDWEbRnBAAfBCuyW2cKK7NAW1QJK7BFL7EpczMztEYEACsEK7AnMrNuRkUIK7RhBAAfBCuwHC+0SgQAHwQrsw1KHAgrtAAEAB8EK7INAAorswANBwkrAbCEL7Be1rRwBQAbBCuwcBCxVwErtE8FABsEK7BPELBkINYRtGwFABsEK7BsL7RkBQAbBCuwTxCxQgErsEcytHMFABsEK7AnMrJCcwors0BCRQkrsEIQtHQFABsEK7BzELF6ASu0NwUAGwQrsjd6CiuzQDcpCSuwNxCwEyDWEbGFASuxV3ARErNbYWduJBc5sGwRsFk5sUJkERKxUlQ5ObBzEbFASDk5sXp0ERK1GRw6SjV/JBc5sDcRszAyTHgkFzmwExKxEC85OQCxfYIRErJPN1c5OTmxdVsRErA1ObBnEbEyWTk5sEUStDFeZGxwJBc5sWFGERKxJhY5ObAcEbMQExlMJBc5MDEBMh4CFRQjIi4DIyIGFRQWFRQGIy4EIyIOCAchFSMOCQcWFRQGIyIuBScmNSM1Mz4BMzIXPgEBFB8BFCMiJjU0NwYjIiY1NDYzMhYVFAYnMj4CNTQjIhUUFiUXMz4BNwI0LgEjBiMeATMyBMg+c0ksFQscJTRcO0B6CRIRCxEWI044HDAkHxUSCgoDBQECFikBCwMNCRIQGBohE4FmVEJoQzEYDgMBAS8vC497eU0igv0NICkJK1wPRk1PZGhpaFcSxxAsNCSGhEABsgh0iXU0LjxDFA/MGXdhPQPYNE1UIRwsPj8sXj4HKwsWEQEsOzopCg8bFiQXKBEkA0ECIQoiDyETHhYZC0VrSV0rOmlOgz46HQxBipldRUz893c8TQafZj13MV5HW1ZgWTvVswoVLR5sbTI3r9ICTYP+PVJFIAZjigAAAAAB/ur+9wAA/+gAGQCRALINAAArsAovsAgztBEEACsEK7ATMgGwGi+wDda0DgUAGwQrsDYauhGKwnMAFSsKsBMuDrAVwAWxCBf5DrAGwLMHCAYTK7ATELMUExUTK7IUExUgiiCKIwYOERI5sgcIBhESOQCzBgcUFS4uLi4BtQYHCBMUFS4uLi4uLrBAGgEAsREKERKwADmwDRGwGTkwMRUOCCMiJjUzFBYzMj4FNwEPBA8KERAVFw5BTUQkJgwUEgoRBBMCyQEQBA4FCwQHAnR9SGgCBgMNAxICAAAAAgBI//MBowFNAAsAFwBOALIDAAArtBUEAEMEK7APL7QJBAA3BCsBsBgvsAbWtBIFABsEK7ASELEMASu0AAUAGwQrsRkBK7EMEhESsQkDOTkAsQ8VERKxBgA5OTAxJRQGIyImNTQ2MzIWBzQmIyIGFRQWMzI2AaNgTUtjZUlIZUk5Kyk7OiorOaBMYWNKR2ZkSSk8PCkqOjoAAAAABABNABcBEQIKAAsAFQAeACkAkACwGS+0KAQAHwQrsCIvtB4EAB8EK7ADL7QTBAAfBCuwDy+0CQQAHwQrAbAqL7Ab1rAGMrQlBQAbBCuwEDKwJRCxDAErsB8ytAAFABsEK7AWMrErASuxJRsRErEZHTk5sAwRsQkDOTmwABKxGB45OQCxKBkRErAXObAiEbAbObAeErAWObEPExESsQYAOTkwMQEUBiMiJjU0NjMyFgc0JiIGFBYzMjYWFAYiJjU0NjIHNCYjIgYVFBYzMgERNispOjsoKTg9FCAWFhAOFj04Ujo6UgUUEBEVFhAkAacpODkoKTo5KhEVFSIUFvdQOjsnKDpiEBUUERAVAAMAWP/yBVACLQA7AEgAWgE7ALIRAAArsiAAACuxAywzM7FYBOmyIAAAK7RGBAArBCuwTC+0TQQAHwQrsEAvtAgEACsEK7AmL7EMFTMztDEEADcEK7E1OTIyAbBbL7Au1rQpBQAbBCuwKRCxIwErtFUFABsEK7BVELFRASu0GAUAMQQrslEYCiuzQFFNCSuwURCwSSDWEbQdBQAxBCuwGBCxEQErtBAFADEEK7AQELEGASu0QwUAGwQrsEMQsTwBK7QABQAbBCuxXAErsSMpERKxKyw5ObFRVREStCAxMyVYJBc5sEkRsBo5sBgSsRU1OTmxEBERErA3ObE8QxEStAMIDDkKJBc5ALFGERESsCs5sUxYERKzBTxDHSQXObBNEbUAGiMuKVUkFzmwQBKxBj45ObAIEbIKGFE5OTmwJhKxN1M5ObAxEbAzOTAxJRQGIyImNDYzMhcmIyIGFREjETQmIx4BFRQHHgEVFAYjIiY1NDcjIgYVFBcHJjU0NjMyFzYzMhc2MzIWBzQnJiMiBhUUFjMyNiE0KwE1MzI2NTQnBhUUFjMyNgVQa1pWbG9VGxhAa0dcUWlZGStLIjFjRWR5eB9gf3A0hLV8SikrS6E5Mp6AtEgcJjc4Rkg5NkD9U2opKSo4V49MQiQ84mWKebSDB0tQRP6tAVFMSQxMIlQXCkYqQVOVbpJeiWOORjRdrH21FxdTU8ecQD0YWDs9WFZNPS0oOihElkxqLgADAFn/HgXyAi4ATABYAGsBegCyIAAAK7IwAAArsRM7MzO0aQQANwQrsFcysgEAACuwAy+0CAQAKwQrsFwvtF0EAB8EK7BRL7QZBAAfBCuwNS+xGyQzM7RABAA3BCuxREgyMgGwbC+wPda0OAUAGwQrsDgQsTMBK7RmBQAbBCuwZhCxYAErtCcFADwEK7JgJwors0BgXAkrsCcQsC0g1hG0WQUAMQQrsFkvtC0FADEEK7AnELEgASu0HwUAMQQrsB8QsRYBK7RUBQAbBCuwVBCxTQErtBAFABsEK7AQELELASu0AAUAGwQrsW0BK7EzOBESsTo7OTmxYGYRErQwQEI1aSQXObBZEbAqObAnErEkRDk5sR8gERKwRjmxVBYRErEbSDk5sE0RtAMIEwUZJBc5sBASsQ5KOTkAsQgDERKwBTmwMBGwBjmxaSARErA6ObBcEbULFgBNVC0kFzmwXRK1ECozPThmJBc5sFERsidPDjk5ObAZErBgObA1EbJGSmM5OTmwQBKwQjkwMSUUBiMiJzcWMzI2NTQmJxYVFAYjIiY1NDYzJiMiBhURIxE0JiMeARUUBgceARUUBiMiJjU0NyIGFRQXByY1NDYzMhc2MzIXNjMyFx4BBzQnJiMiBhUUFjMyJTQmIzUyNjU0JicOARUUFjMyNgXyqIZOSB04P2eHTkEbXVtWXHVeNllJWlFjWBwhJiUkL19GanZ1cI5zNISze1AqKkiXQz2IpElxgv0kEghHVjgycf1nTEdCRysmOllNQSQ8eZDLLz0rpXBXgxQ0TGqCbl1khjtPRP6tAVFITRdFIyQ2DApELEJPjHSNY4ZmjkgyXK18txgYVFSBDacoWz4CYUs6TFMuHz0zJB0zDQ2DR0trLgAAAAIAV/8nA9UCLQA6AEYA8QCyBAAAK7QSBAArBCuyEAAAK7ANL7QKBAA3BCuwLi+0RAQANwQrsD4vtCgEACsEK7AiL7AZM7Q0BAA3BCuwODKyIjQKK7NAIh0JKwGwRy+wMdaxQQXpsEEQsAcg1hG0EAUAJgQrsBAvtAcFACYEK7BBELE7ASu0KwUAJgQrsCsQsR4BK7EdBemwHRCxFgErsQAF6bFIASuxQRARErAlObE7BxEStQQSKC4+RCQXObArEbEiNDk5sR0eERKwNjmwFhGyEwM4OTk5sAASsQsMOTkAsQQKERKwDzmxPkQRErQAFisxJSQXObEiKBESsDY5MDEBFAYjISIGFRQWMyEVISImNDYzITI2NTQmIyIGHQEjNTQmIyIGBz4BMzIWFRQGIyImNTQ2MzIXNjMyFgU0JiMiBhUUFjMyNgPVrnr+ZiU3NCYCuf08RFpZRQGVXYheUjU/WGlBS2UHBEMsPUxcRU9YkHmSPCx6eYj9fysmIzQtJCcwARZ2oCggIihHUIJKeFhbeFk93t49WUpBIiddQkVac1p2hFxcmJUqODUjKDYt//8AV/8nBsACLhAnBswD7AAAEAYGigAAAAIAWv8pAtACLgAqADUAqQCwCy+0CAQANwQrsAMvtBEEACsEK7AiL7QzBAArBCuwLi+0HAQAHwQrsBcvsSgE6QGwNi+wJda0MQUAPAQrsBoysA4g1hGxBQXpsDEQsSsBK7EfBemwHxCxFAErsQAF6bE3ASuxKwURErUDERwiLjMkFzmwHxGyEhcoOTk5sBQSsAI5sAARsQkKOTkAsQMIERKwDjmxLjMRErMUHyUAJBc5sBwRsBo5MDEBECEjIhUUFjMhFSEiJjU0NjsBMjU0JiMiBgc2MzIWFRQGIyImNTQ2MzIWBTQmIyIGFBYzMjYC0P7np1UyIwG0/j9CW1lEo9SLckxxEB9IQVVeSE9eqYeStP6HLSUmMjImJS0BB/76RSEqSFJBP0jGZ3RBNzRYQkdYaVN9jp6KKDQ0TjQzAAD//wBa/ykFwQIuECcGzALtAAAQBgaMAAAABABX/xkDYQIuADAAPABHAFIA9wCwCy+xTgTpsEovsSME6bAoL7AeM7Q6BAA3BCuwRTKwQC+wNDOxGATpsC4yAbBTL7AV1rFDBem0IQUAGwQrsEMQsEwg1hG0DwUAPAQrsA8vtEwFADwEK7BDELE9ASu0GwUAJgQrsBsQsSsBK7Q3BQAbBCuwNxCxSAErsDEysQYF6bAGELAAINYRtCUFABsEK7AlL7QABQAbBCuxVAErsT1MERK1EhgeEUBFJBc5sBsRsAs5sCsSsiNKTjk5ObA3EbAKObBIErUEKC40AzokFzkAsUpOERKxDwY5ObAjEbMDERIEJBc5sUA6ERK1ABUbJSshJBc5MDEBFAYHFRYVFA4CIi4CNTQ3NS4BNTQ2MzIWFRQGIyImJxQhIDUOASMiJjU0NjMyFgc0JiMiBhUUFjMyNiU0JiMiBhUUFjI2ATQhIBUUITI+AgNhV0aKQnF7jHhtP4dMVGRYRVlWQSpECwE5AT0JRSw/VFlFU2ZkMSclMjMkJzH+aS8nJjM0SjEBlP7g/ukBFzBdWzgBVFaHCAgYejRNKBMSKE01ehgFD31eYHhdRkNcMSO2tiUvXkNGW34iJjAwJCU4NCcmMDAkJTg2/mxoaG4KFy4AAAAAAwBZ//YEIwIuAC8AOABDANEAshMAACuyIwAAK7ADM7RBBAA3BCuwNzKwMy+wOzOxCATpsB0ysBcvsA4zsSkE6bAtMgGwRC+wJtaxPgXpsD4QsTkBK7QgBQA8BCuwIBCxEwErtBIFACYEK7ASELEGASu0NgUAPAQrsDYQsTEBK7EABemxRQErsT4mERKxGRo5ObA5EbIdKSM5OTmwIBKwFzmxEhMRErArObE2BhESsA45sDERsggtAzk5ObAAErELDDk5ALEzQREStAUGACYgJBc5sAgRsQsaOTmwFxKwKzkwMSUUBiMiJjQ2MzIWFy4BIyIGFREjETQmIyIGBz4BMzIWFRQGIyImNTQ2MzIXNjMyFgY0JiMiBhQWMiU0JiIGFRQWMzI2BCNqYUlqYUgsUA0Gf1tAUk9SQFt/Bg1QLElgZE9gaqB/hUBChnujYD8pKDs5VP3+OlI+PSorOOlriGGYayogWHxIPf6hAV89SHxYICprTE5fiGuHvlJSwfZUPkBSOmMqPz8pKjo4AAAAAAIAWf8jBLMCLwA0ADsA7gCyGQAAK7EkNjMztC0EACsEK7AOMrIZAAArtBoEABMEK7AVL7ACM7E5BOmwHy+0KQQAKwQrsBAysAgvtDMEAEMEKwGwPC+wJta0IQUAGwQrsCEQsRwBK7QrBQAbBCuyHCsKK7NAHBkJK7ArELEuASuwGDK0DgUAPAQrsTcF6bAOELE1ASuwDzK0EgUAMQQrsBIQsQYBK7QABQAxBCuxPQErsRwhERKzIyQoKSQXObArEbAtObE1NxESsBU5sBIRsQgzOTmwBhKxAgM5OQCxORURErADObEaGRESsCM5sR8tERK1BgAcISYrJBc5MDElFAcnPgE1ECMiDgIdATMRMxEUBiMiJicjNTY1NCYiBhUUFwcmNTQ2MhYVFAczNTQ+ATMgATUjFjMyNgSziTU7M9E8Vi8WpVFYQkpWDfdMV3RWWS9vd8B4IIA5iWgBIf6tngpPHieP4IwzRYdtAVc5ZXhJRgEz/l9HZn5cKiRbOE9MOGQeLjh4W25uW0YlRnu4df2UPY0wAAAAAAIAWP8iBM8CLgBHAE4BGQCyMAAAK7IkAAArsEkztDoEACsEK7AaMrIkAAArtCUEABMEK7ACL7EHBOmwTDKwBxCxIQTpsA0vsQ4E6bAqL7Q1BAArBCuwHDKwFS+xQATpAbBPL7Ay1rQtBQAbBCuwLRCxJwErtDgFABsEK7InOAors0AnJAkrsDgQsTsBK7AjMrQaBQAmBCu0SgUAMQQrsBoQsRsBK7BIMrQeBQAmBCuwHhCxCQErsBIytAAFACYEK7BDMrFQASuxJy0RErIvMDU5OTmwOBGwOjmxG0oRErAhObAeEbAVObAJErQCBA1ARiQXOQCxBwIRErAEObAwEbIABQk5OTmxJSQRErAvObEODREStCctMjhGJBc5sTUqERKxEkM5OTAxBRQjIic1FjMyNTQmKwE1MzI2NTQmIyIOAR0BMxEzERQGIyInIzU2NTQmIyIGFRQXByY1NDYzMhYVFAczNTQ+ATMyFhUUBgcWBTUjFjMyNgTPohIqFhxhOjEgIChDd15SdDSrT1hAkBv6TFk4OlZYM2qAV1aBH4JHl2mAnywgTP6QogxOHiodug1TE20zRlFeLVNZY5tfRgEz/lNCY94vIlg3UEw4YSA1OnxUdXZTRiVGdrx1gnY1ZBM2lECQMAD//wBZ/yMHbgIvECYGxAAAEAcGkAK7AAAAAgBW//MCygIvAC0AOQDAALIgAAArsAMztDcEACsEK7AIMrAOL7EPBOmwDxCwGiDWEbQxBAAfBCuwFS+xJgTpAbA6L7Aj1rE0Bem0GAUAJgQrsDQQsS4BK7QdBQAmBCuwHRCxCgErsBMytAAFACYEK7AqMrIKAAors0AKDgkrsAUysTsBK7E0GBESsBc5sC4RsRogOTmwHRKwFTmwChGxAyY5ObAAErAsOQCxDjcRErUABh0jLjQkFzmxDzERErEYLDk5sRUaERKxEyo5OTAxJRQGIyInNRYzMjU0JisBNTMyNjU0IyIGBzYzMhYVFAYjIiY1NDYzMh4BFRQHFgU0JiMiBhUUFjMyNgLKU0QnJRskVTAkPzgkNdJvkAQoREdXX0lXWbuoSnZORkn+lTEoKTEzKicvg0JODEkSUSY4TychaGtiMF1KSWSMZqKoIlM+UhseVC09OSstQD3//wBW//MEqwIvECcGvQKxAAAQBgaTAAD//wBW//MFtwIvECcGzALjAAAQBgaTAAAABABZ//IDugIuACYALwA2AEEArwCyFAAAK7EDEDMztD8EACsEK7EINTIysDovsQwxMzO0GgQAQwQrsSMnMjKwKy+0HwQANwQrAbBCL7AX1rQ8BQAbBCuwPBCxOAErsBsytDMFACYEK7AuMrAzELEwASuwJzK0DgUAMQQrsCIysA4QsQoBK7QABQAxBCuxQwErsTg8ERKxFD85ObAzEbASObAwErEfEDk5sQoOERKxAwU5OQCxOj8RErMABhIXJBc5MDElFAYjIic1FjMyNTQrARUUIyInBiMiJjU0NjsBNTQ2MzIWHQEzMhYlNTQmIyIGHQEXNSMVFDMyJSc1IyIVFBYzMjYDulZQIhobFmFzK8R2JhtgSFBmSzhyWVJtNlBo/sFEMzRC7e14df7LBCd7LyghLqhUYgpKD25eGfhRUWNOSl8YWHJ2VBhZWRY2TlA3E10UFrdeWBdfLUA5AAAAAAIAV//zA44CLQAgACsAtwCyAQAAK7QdBAArBCuyEgAAK7QpBAArBCuyHQEKK7NAHR8JK7QMJBIfDSu0DAQANwQrsAcvtBgEADcEKwGwLC+wFdaxJgXptAoFACYEK7AmELEhASu0DwUAGwQrsA8QsQQBK7EbBemyBBsKK7NABAEJK7AbELEeASu0AAUAMQQrsS0BK7EhJhESsRIMOTmwDxGxBxg5ObEbBBESsB05ALEdKRESsAI5sCQRtgQPFRsKISYkFzkwMSkBNTY1NCYjIgYVNjMyFhUUBiMiJjU0NjMyFhUUBzMRMwE0JiIGFRQWMzI2A47+dll0YFyKHlVHV1dGXWOsiIGlPstQ/d4zUDIzJykyOjmHZoeIXEdjSklhhGmQvbKEdz8B3/59Kjw9Kyk8PAAAAQBZ//MDjgIyACEAewCyDgAAK7ACM7EZBOmwCC+0HwQAQwQrAbAiL7AR1rQWBQAxBCuwFhCxGwErtAsFACYEK7ALELEFASu0AAUAGwQrsSMBK7EbFhESshMOFDk5ObEFCxESsgIDHzk5OQCxGQ4RErADObAIEbUABQsRFhwkFzmwHxKwFDkwMQEUByc2NTQmIyIdARQGIyImNTQ3FwYVFBYzMjUnNDYzMhYDjqQ0jlxNe3lebISlModZSoUBcVlzgQEHvlYzP6xZesRQYH2jdtRSMkKnVoS5Xlx9pQAAAAACAFkAAAU/Ai4AJQAuANgAsgEAACu0IgQAKwQrsiIBCiuzQCIkCSu0AxgBJA0rsCYztAMEACsEK7AgMrADELQEBAATBCuwCS+wKjO0EwQANwQrsBwyAbAvL7AQ1rQLBQAbBCuwCxCxBgErtBYFABsEK7IGFgors0AGAwkrsBYQsQEBK7AZMrEiBemwLTKwIhCxJgErtCAFADwEK7AgELEjASu0AAUAJgQrsTABK7EGCxESsg0OEzk5ObAWEbAYObEmIhESsR0cOTkAsQMiERKwDjmxGAQRErANObAJEbMGCxAWJBc5MDEpATUjNTY1NCYiBhUUFwcmNTQ2MzIWFRQHMzU0NjIWHQEhFSERMwE1NCYjIgYdAQU//Sn1TFd0VkkhbYBXVoEfgJLajP5dAjNP/s9ZTE5duigkXDhMSjhSIjw2elR2dlRHIk9mfn1nkHkB3/7bOU9jYlA5AAACAFf/8wPqAi0AOgBEAO4AshkAACuwBTOyAwAAK7ApM7QIBAA3BCuwQjKwGRC0BgQAQwQrsA4vtA8EADcEK7APELAjINYRtD4EACsEK7AeL7AVM7QvBABDBCuwMzIBsEUvsCzWsUAF6bQhBQAbBCuwQBCxOwErtCYFADwEK7AmELEaASu0GQUAMQQrsBkQsQsBK7ASMrQABQAmBCuwNjKyCwAKK7NACw4JK7FGASuxO0ARErEjKTk5sCYRsR4vOTmxGRoRErAxObALEbMDBTM5JBc5ALEOBhEStQALJiw7QCQXObA+EbAhObAPErA5ObEeIxESshIxNjk5OTAxJRQGIyInNRYzMjY1NCsBNTMyNTQmIyIGFREnETQmIyIGFTYzMhYVFAYjIiY1NDYzMhc2MzIWFRQGBxYFNCYiBhUUFjI2A+poSjs2FVUtPW9ZV3FVOkdoUF4+WncaXklbZExXXpyEeEhCkVmHLiJQ/X8xUjQ1TDaTR1kOSRAyK1lHUC0wPjj+kgEBbTRCgl9GXUlLZY1pjrZOTlhLKUEJG18sPDsqKD48AAAAAQBaAAADYQIgABsAggCyAQAAK7QCBAArBCuwGDKyAgEKK7NAAhoJK7QUCQEaDSuxFATpAbAcL7AR1rQMBQAbBCuwDBCxBgErtBcFACYEK7IGFwors0AGAQkrsBcQsRkBK7QABQAxBCuxHQErsQwRERKwDzmwBhGxDhQ5ObAXErAYOQCxCQIRErEPFjk5MDEpATUhMjY1NCYjIgYVFBcHJic0NjMyFhQHMxEzA2H8+QFHMEtELi9EDU4IAXNOTG044lBDSC4tQEEuHBcDGR1NbGuYKgHdAAAAAgBa//IFAQItADYAQgD2ALIWAAArtBcEACsEK7AuMrIDAAArsUAE6bIWAAArtBQEABMEK7AeL7QpBAA3BCuzOykeCCu0CQQAKwQrsA0vtDQEADcEKwGwQy+wJta0IQUAGwQrsCEQsRsBK7QsBQAbBCuyGywKK7NAGxYJK7AsELExASu0EAUAGwQrshAxCiuzQBAVCSuwEBCxBgErtD4FABsEK7A+ELE3ASu0AAUAGwQrsUQBK7EhJhESsCQ5sBsRsSMpOTmwLBKwLjmxEDERErAvObE3PhEStAkDDTQLJBc5ALEeFxESQAkABiQmLDE3PT4kFzmwOxGwOTmxCSkRErALOTAxJRQGIyImNTQ2MzIXJiMiBgcUFxYXFSE1ITI2NTQmIyIGFRQXByY1NDYzMhYVFAczJjU0NjMyFgc0JyYjIgYUFjMyNgUBcl1Qa29dFR89bGOFAkYMJP0AAUcwTUQwMUYPTAlzTktrNp4usn5/tEocITw3SkA3OEvlZ4x/VWF9B0mFY4I5CwYyQ0guL0JDMBwYAhgeTWxoT1ElRnp9rcSfPz4YWHZVVQAEAFf/8gNJAi0ANQA+AEcATgETALIIAAArsAMztE0EACsEK7A8MrBJL7QNBAArBCuwJi+0RgQAHwQrsEIvtCAEABMEK7AcL7AVM7QrBAA3BCuwLzIBsE8vsCjWtEQFABsEK7ALINYRtEsFABsEK7BEELE/ASu0IwUAGwQrsCMQsRkBK7QYBQAxBCuwGBCxEgErtDIFACYEK7AAMrAyELQ2BQAbBCuwNi+xUAErsUtEERKwJjmwPxG0ICUeQkYkFzmwIxKzCBwrTSQXObAZEbANObAYErAtObASEbcGDgMvODo9SCQXObEyNhESsDQ5ALFJTREStAALNjoGJBc5sA0RsTQ4OTmwRhKxGBk5ObBCEbMSKDIjJBc5sCASsB45sBwRsC05MDElFAYjIiYnBiMiJjU0OwEyNzY1NCYjIh0BIzU0IyIHNjMyFhUUBiImNTQ2MzIXNjMyFhUUBxYHNCMiFRQWMjYBNCYiBhUUMzIFIyIVFDMyA0lSOjBLC026Zmr421A2P0A1c1CTXRcTES43RGJFeWF+Ny58VmE9P0dFRyo6KP4DIDAhODkBLqPmkMB8OlAzJlk0QYUeIkU1QW11b3MkCz8wMUJJO1lkTExrWFEwKkM+PhwpKQEDGCQjGDt/QDMAAgBZ//IGAAIvAEMATQDuALIIAAArsgMXJDMzM7Q0BABDBCuxPUsyMrI0CAors0A0OAkrsB4vsA8ztCkEADcEK7EtQjIyAbBOL7Am1rQhBQAmBCuwIRCxGgErtEgFACYEK7BIELFEASuxFAXpsBQQsQsBK7QxBQAmBCuwMRCxNwErtDoFADEEK7A6ELE/ASu0AAUAJgQrsU8BK7EaIRESsSMkOTmwSBGwHjmwRBK0FxEpKxwkFzmwFBGxDy05ObE3MRESsAg5sDoRsAU5sD8SsgNBQjk5OQCxNAgRErAjObAeEUAMAAsFFBohJjA/REZIJBc5sCkSsStBOTkwMQEUBiMiJw4BIyImPQE0JiMiBx4BFRQGIyImNTQ3JiMiBhUUFwcmNTQ2MzIXNjMyFh0BFBYzMjY1ETMRFBYzMjU0JzcWBTQnBhUUFjMyNgYAeGpXMBNNLF+LcU0hHi1IbkxRaHogI1BoajKEonw7MTFeaJNZRC00UDMqnX4zlvxBYmo3My8zAQ14oEsgLXJYcUxsCieQRVeWj16ZYA2JWpBPMly8fqYmJnxhd0RaUjgBXv6iNFbNrUcyW/R6W02IQmdoAAMAV//yBT4CLQA7AEUAUAECALIcAAArshAAACuxAiszM7RDBAArBCuwTjKwSS+0JQQAKwQrsCAvsQgXMzO0MQQANwQrsTU5MjIBsFEvsC7WsUwF6bBMELFGASu0KAUAMQQrsCgQsRwBK7EbBemwGxCxEwErtEAFACYEK7BAELE8ASu0DQUAPAQrsA0QsQUBK7QABQAmBCuxUgErsUwuERKxIiM5ObBGEbElKzk5sCgSsSAxOTmxGxwRErAzObFAExESsRc1OTmwPBGzEAo3FSQXObANErEIOTk5sAURsQIDOTkAsUMcERKwAzmwSRG3BQ0TKC48QCMkFzmwJRKwADmwIBGzChUzPiQXObAxErA3OTAxARQHJzY1NCYjIgceARUUBiMiJjU0NyYjIgYVESMRNCYjIgYHNjMyFhUUBiMiJjU0NjMyFzYzMhc2MzIWBTQnBhUUFjMyNiU0JiMiBhQWMzI2BT6LLmyAVyIhL0trWFpleigaP1haZj9VdgYbX0haYEtWZJ6Ch0ZCkDhAQ1Z2of7AcHQ8ODQ8/W4zKis0NSopNAEKvVsuS5haiQwmjkZjioNjm2MPQTj+kAFwNUSJWkZeSEtlkGaLuU5OJiaronJjUoNEZWcCLDs6WDw8AAEAWf/yAk0CLgAhAHoAsgMAACu0CAQANwQrsA4vsR4E6bAZL7QUBAA3BCsBsCIvsBHWsAUytBwFADEEK7AcELELASu0AAUAMQQrsBYysSMBK7EcERESsAY5sAsRtQMIDhQZHyQXObAAErAXOQCxDggRErIFAAY5OTmxGR4RErIWERc5OTkwMSUUBiMiJzcWMzI2NTQrASImNTQ2MzIXByYjIgYVFDsBMhYCTYlnq1kxQo9CYHliWHGJaKpZMUSOQV95aFZsnlRYXTVKMzFJT0xVV101SjMxTkwAAAACAFn/8wKaAi4ACAAUAFAAsgMAACuxEgTpsAwvtAgEADcEKwGwFS+wBta0DwUAGwQrsA8QsQkBK7QBBQAbBCuxFgErsQkPERKyBwgDOTk5ALEMEhESswEFBgAkFzkwMQAUBiMiJjQ2MhM0JiMiBhUUFjMyNgKaq3d2qajuYX9ZWH1+V1iAAYfsqKjsp/7jWH19WFd9fQAAAAEAV//wBQsCNAAwAJwAsgcAACuxAxQzM7EgBOmwKTKwDi+0GQQANwQrAbAxL7AW1rQRBQAbBCuwERCxCgErtB0FADwEK7AdELEjASuxJgXpsCYQsSwBK7QABQAmBCuxMgErsQoRERKyExQZOTk5sSMdERKwBzmwJhGwBTmwLBKyAy4vOTk5ALEgBxESsBM5sA4RtgAKBREWHCwkFzmwGRKyJCUuOTk5MDEBFAYjIicGIyImPQE0JiMiBhUUFwcmNTQ2MzIWHQEUFjMyNjURMxEUFjMyNjU0JzcWBQuIb3c6OXFog0k+TVyEKqGCbmZzTkU5S1RVOUtZfSijARB5pFhYgGRoRGOEW5tEOFfCfKmTclVGUU47AV7+ojdSeVelRztXAAACAFn/8gU0Ai4ANwBDANkAsgMAACuxBxQzM7QpBAA3BCuwIDKwLy+0QQQANwQrsA4vsDsztBkEADcEK7A1MgGwRC+wFta0EQUAGwQrsBEQsQoBK7QdBQAbBCuwHRCxIwErtCYFADEEK7AmELEyASu0PgUAJgQrsD4QsTgBK7EABemxRQErsQoRERKyExQZOTk5sSMdERKwBzmwJhGwBTmxPjIRErADObA4EbIpLzU5OTmwABKxKyw5OQCxKQMRErATObAvEbEdBTk5sEESshEWCjk5ObAOEbIALDI5OTmwGRKxJCU5OTAxARQGIyInBiMiJjU0JyYjIgYVFBcHJjU0NjMyFxYVFBYzMjY1ETMRFBYzMjY3DgEjIiY1NDYzMhYHNCYjIgYVFBYzMjYFNKF/kUY/aGdwChZiTFN/I6F6c4cpEks9OExQb0dZaQgMSilFWmJLWmdgOygpNDQnKjsBOom/UlF6aoolYYJelkQ6VsCDonQ6rEBXWDoBUf6dO0iCYh4sZEhLY4wgKTw5Kyo/PQAAAAIAV//yBS4CLgAyAD4A1wCyFQAAK7ALM7IjAAArsAIztDwEADcEK7A2L7QdBAArBCuwGC+xCBAzM7QoBAA3BCuxLDAyMgGwPy+wJdaxOQXpsDkQsTMBK7QgBQAmBCuwIBCxFQErsRQF6bAUELEMASu0CwUAMQQrsAsQsQUBK7QABQAmBCuxQAErsTklERKxGhs5ObAzEbEdIzk5sCASsRgoOTmxFBURErAqObAMEbAsObALErAuObAFEbICAzA5OTkAsTwVERKwAzmwNhGyICUbOTk5sB0SsQAFOTmwGBGxKi45OTAxARQHJzY1NCYjIhURIxE0JiMiBhURIxE0IyIGBzYzMhYVFAYjIjU0NjMyFzYzMhc2MzIWBTQmIyIGFRQWMzI2BS6iJ3xeUm5QSz49SFWmVHIGG1tEWV1ItaOFeEI7eG8/M2xvhvw2MSkqMzQoKTIBFs1XPUOmW3OH/qEBXz9JSj7+oQFfh4pZRmBGS2b3i7pNTUtLoPAsPTosKz06AAACAFf/8gO6Ai0AKAAzAKkAshAAACuxAh0zM7QxBAArBCuwFy+wCDO0IgQANwQrsCYyAbA0L7Af1rQaBQAmBCuwGhCxEwErtC8FACYEK7AvELEpASuxDQXpsA0QsQUBK7QABQAmBCuxNQErsRMaERKxHB05ObAvEbEXIjk5sCkSsxAKJBUkFzmwDRGxCCY5ObAFErECAzk5ALExEBESsQMcOTmwFxG2BQANExofLCQXObAiErAkOTAxARQHJzY1NCYjIgceARUUBiMiJjU0NyYjIgYVFBcHJjU0NjMyFzYzMhYFNCYnDgEVFDMyNgO6jC5tgVgWJDBDclFaaXkjKFl5cDGLtYVNMzZbd6H+v0EuMUR1NDsBCrtdL0yWWokKJZNNWYuBY6FhDYZdl0wuW71/pCoqqqxDeiAheESgYAAAAAIAVwAAAzcCLgAMABUAXgCyAQAAK7QEBAArBCuwDTKyBAEKK7NABAIJK7ARL7QJBAA3BCsBsBYvsAHWtAQFADEEK7AEELEFASu0FQUAMQQrsBUQsQ0BK7QABQAxBCuxFwErsQ0VERKwCTkAMDEpAREzETM1NDYzMhYVAxE0JiMiBh0BAzf9IFGrjmNljlBhQkFfAib+Hf1ji4Vi/vwBAEJhYkL/AAAAAAEAWf/zAmoCLQAoAJMAsgMAACuwHDO0CQQANwQrsA8vtBAEAEMEK7AWL7QhBABDBCsBsCkvsB7WtBkFABsEK7AZELEMASuwEzK0AAUAJgQrsCQysgwACiuzQAwQCSuxKgErsRkeERKwHDmwDBGzAwUbISQXObAAErAnOQCxCQMRErEFGzk5sA8RsgAGGTk5ObAQErEeJzk5sBYRsCQ5MDElFAYjIic1HgEzMjY1NCsBNTMyNTQmIyIGFRQXByY1NDYzMhYVFAYHFgJqaEtOIhgiMC0+cVpZclY7bH45RjujjluFLx5Nk0dZDkkKBjIrWElPLTCIcGh7Fn9/kKxXTCZHCiAAAQBZ//IDoAIuACQAWgCyBwAAK7ADM7ETBOmwHDIBsCUvsArWtBAFADEEK7AQELEWASuxGQXpsBkQsR8BK7QABQAxBCuxJgErsRYQERKyDQcOOTk5sBkRsAU5sB8SsgMhIjk5OQAwMQEUBiMiJwYjIiY1NDY3FwYVFBYzMjY1ETMRFBYzMjY1NCc3HgEDoJBzcjI1bG+QX04mg2ZRLj9USTROZIQoTV8BEHmkU1SjdWaZJT0/rVZyUTMBYP6gNU95VKo9PSSWAAABAFn/8gOgAi4AJAB2ALIOAAArsQMYMzOwCS+wEjO0IgQANwQrsB4yAbAlL7Ab1rQVBQAxBCuwFRCxDgErtA0FADwEK7ANELEGASu0AAUAJgQrsSYBK7EOFRESshcYHjk5ObANEbAgObAGErIDBCI5OTkAsQkOERK0BAAXGyAkFzkwMQEUBgcnNjU0JiMiBhURIxE0JiMiBhUUFwcuATU0NjMyFzYzMhYDoF1PJYJkUzE+Ukk1TmOJLU1gknJxMzNtcI8BF2iYJTtArld0SzX+mgFmNEp4Vq0/OCWVZXilTk6hAAACADn/8gOgAi4AKAA0ALcAsg4AACuyHQAAK7ADM7QyBAA3BCuwLC+0FwQAKwQrsAkvsBIztCYEADcEK7AiMgGwNS+wH9axLwXpsC8QsSkBK7QaBQAmBCuwGhCxDgErtA0FADwEK7ANELEGASu0AAUAJgQrsTYBK7EvHxESsRQVOTmwKRGxFx05ObAaErESIjk5sQ0OERKwJDmwBhGyAwQmOTk5ALEyDhESsAQ5sCwRshofFTk5ObAXErEABjk5sAkRsCQ5MDEBFAYHJzY1NCYjIgYVESMRNCYjIgYHNjMyFhUUBiMiNTQ2MzIXNjMyFgU0JiMiBhUUFjMyNgOgXU8lgmRTMT5SSDNXgQYbW0RZXUi1n4RyMzNtcI/9pjEpKjM0KCkyARdomCU7QK5XdEs1/poBZjRKiVhGYEZLZveMuU5Ooe8sPTosKz06AAEAWf/8A1cCIAAaAJYAsgEAACuwDTO0FwQAKwQrsgEAACu0AgQAEwQrsgIBCiuzQAIZCSu0EgcNGQ0rtBIEAEMEKwGwGy+wD9a0CgUAGwQrsAoQsQQBK7QVBQAmBCuwFRCxGAErtAAFACYEK7IYAAors0AYAQkrsRwBK7EEChESsgwNEjk5ObAVEbAXOQCxFwIRErAMObAHEbMECg8VJBc5MDEpASc2NTQmIyIGFRQXByY1NDYzMhYVFAchETMDV/4cAklTOThVSCFvgFdYgB4BH04vJVU3TEs1UiE9OHhUdXFYOTIB3wACAFn//AR3Ai0AHgAnAKAAsgEAACuwDDO0FgQAKwQrsB8ysAcvtBEEACsEK7AjL7QbBAA3BCsBsCgvsA7WtAkFABsEK7AJELEEASu0FAUAGwQrsgQUCiuzQAQBCSuwFBCxFwErtCcFADEEK7AnELEfASu0AAUAGwQrsSkBK7EECRESsgsMETk5ObAUEbAWObEfJxESsBs5ALEWARESsQILOTmwBxGzBAkOFCQXOTAxKQE1NjU0JiIGFRQXByY1NDYzMhYVFAczNTQ2MzIWFQM1NCYjIgYdAQR3/PxMV3RWSyFvgFdbex62hGhhjEpfREJaKihXOE9LOVYjNzh4VHVxWEgj/GiIimD+/v5EY2RD/gAAAAACAFf/8wSzAi0ALQA3AOoAsgEAACuwDDO0KgQAKwQrshwAACu0NgQAQwQrsioBCiuzQCosCSu0FjEcLA0rtBYEACsEK7ARL7AIM7QhBAA3BCuwJTIBsDgvsB7WsTMF6bAzELEuASu0GQUAJgQrsBkQsQ0BK7QMBQA8BCuwDBCxBQErtCgFACYEK7IFKAors0AFAQkrsCgQsSsBK7QABQAxBCuxOQErsTMeERKwFDmwLhGxFhw5ObAZErERITk5sQwNERKwIzmwBRGwJTmwKBKwKjkAsTYBERKwAjmxMSoRErQZHhQuMyQXObAWEbEFKDk5sBESsCM5MDEpATU+ATU0JiMiBhURIxE0JiMiBgc2MzIWFRQGIyI1NDYzMhc2MzIWFRQHMxEzATQmIgYVFBYyNgSz/lczRlhKNT1TZkVbaw4aXUdVYUmvo4l/QURReoBH2FD8rzBSMzFSMi8kgUlUdUg4/poBbTlAgGNGX0pJZOuTvElJm4V2VgHf/n0sPDssKzc2AAAAAAEAWf/tAoQCLwA4ALcAsgMAACuwIjO0CAQANwQrsAsvsTYE6bAzMrAvL7AsM7ETBOmwFjKwHC+0JwQANwQrAbA5L7Ak1rQfBQAbBCuwHxCxEQErsTEF6bAxELEKASuwGTKxAAXpsCkysToBK7EfJBESsCI5sBERsQYhOTmwMRKwBTmwChG3AwgOExwnLDYkFzkAsQgDERKxBSE5ObALEbEABjk5sDYSsBA5sC8Rsh8kMTk5ObATErARObAcEbEZKTk5MDElFAYjIi8BFjMyNCMiBiMiJjQ2MzIWMzI2NTQmIyIGFRQXByY1NDYzMhUUBiMiJiMiFRQzMjYzMhYChGplXj0HQHFqSgpICi9CSS0ZOhkYHV09dH0wRzOolO5UOA0yDT8/DTgMNVNnQTMWUB9aA0JcSAYcDyckjXhSihmEiZCllTJBBSkoBUcAAwBXAAACdAIuAAYADwAXAGIAsgEAACu0DwQAKwQrsBIvsQQE6QGwGC+wAda0FgUAGwQrsBYQsRABK7EMBemwDBCxBwErtAAFACYEK7EZASuxEBYRErEEDzk5sAwRsAo5ALESDxESsQwWOTmwBBGwCjkwMSkBNRAhIBEHNTQnFhUUBgcTNCMiBh0BNgJ0/eMBEgELTJ0+ZkVWR0RI0/sBM/7Tvr7OGB1kU5s1ASlugFm5hQAAAwBa//AD/gItAB8AKgA2AKgAsgMAACuwBzO0GAQAKwQrsDUysC8vsCMztA0EAEMEK7ERHjIyAbA3L7AK1rQyBQAmBCuwMhCxLQErtCYFACYEK7AmELEgASu0FAUAMQQrsBQQsRsBK7QABQAmBCuxOAErsS0yERKwDTmwJhGyBw81OTk5sCAStQMRBRgWKyQXObEbFBESsR0eOTkAsRgDERKwBTmwLxG1CgAUDxsoJBc5sA0SsB05MDEBFAYHIicGIyImNTQ2MzIXNjMyFhUUBxYzMjY1NCc3FgU0JiMiBhUUFz4BByY1NCMiBhUUFjMyA/6zklkgKF+ZxmFUYy03fVZ2hhUcZIJWPWf+0UZEQUeGOFThfmEuOJdxHAEuj60CIB63lGSMTk6LW7BgBJVpe04zY51RZmJMm0UaeK9ln6drPHKYAAAAAAIAWv/zAswCLgAaACcAfQCyAwAAK7ATM7ElBOmwHy+xCQTpsA0vtBgEADcEKwGwKC+wFda0EAUAGwQrsBAQsQYBK7QiBQAmBCuwIhCxGwErsQAF6bEpASuxBhARErESEzk5sRsiERK0CQMNGAskFzkAsSUDERKwEjmwHxGzABAVBiQXObAJErALOTAxJRQGIyImNTQ2MzIXJiMiBhUUFwcmNTQ2MzIWBzQnJiMiBhUUFjMyNgLMgF5aXX9aHBk7bWuOYjN5sY2OplUQHjM7VTg3OUniYo15YVl9B0qGZopKMV+tg6q3rUc2D002QVRSAAEAWf/zApYCLQAWAE4Asg4AACuwAzOwCS+0FAQAQwQrAbAXL7AR1rQLBQAbBCuwCxCxBgErtAAFACYEK7EYASuxBgsRErQDBA0OFCQXOQCxCQ4RErEAETk5MDEBFAYHJzY1NCYiBhUUFwcuATU0NjMyFgKWZ1Mgj3y2eZEhUmWlen2hAQNijSE6NqBdhINeojQ6II5ifa2rAAAAAAIAWQAAA1cCLQAOABYAbACyAQAAK7QLBAArBCuyCwEKK7NACw0JK7QKFgENDSu0CgQAKwQrsBMvtAUEADcEKwGwFy+wAda0CwUAMQQrsBUysAsQsQ8BK7QJBQA8BCuwCRCxDAErtAAFADEEK7EYASuxDwsRErAFOQAwMSkBETQ2MzIWHQEhFSERMwE1NCYiBh0BA1f9ApdkbY/+WgJdUP6nXJheAUpfhH1mm2wB3f7TQU9jZE5BAAACAFb/MALKAi8AOQBFANcAsgQAACu0EgQAKwQrsA0vtAoEACsEK7AsL7RDBAArBCuwGC+xGQTpsD0vtCYEADcEK7AhL7QyBAA3BCsBsEYvsC/WsUAF6bAHMrBAELQQBQAmBCuwEC+wQBCxOgErsSkF6bApELEVASuwHDK0AAUAPAQrsDYysUcBK7FAEBESsCQ5sDoRswQSJiwkFzmwKRKwITmwFRGzAxMYMiQXObAAErILDDg5OTkAsQQKERKwEDmxQywRErEVADk5sRkYERK0KS84OkAkFzmxJj0RErIcJDY5OTkwMSUUBiMhIgYVFBYzIRUhIiY1NDMhMjU0KwE1MzI1NC4CIyIGBzYzMhYVFAYjIiY1NDYzMh4BFRQHFgU0JiMiBhUUFjMyNgLKaEj++SY5OSYBp/5MRVmhAP9vWigoVy1HTSVdhhAsPz5YWkJQWraRTIJcRkn+fSshICwuIR8qlkJUJyEfJURIQItUU0pIGysYDVdJOFU9P01tV4CKI1Q8TyAcBSEqKB8hKykAAgBa//MCgQIzACsANQC2ALIJAAArtA4EACsEK7AVL7QhBAA3BCuwLy+0KQQANwQrAbA2L7AY1rQeBQAbBCuwHhCxJgErtDIFADwEK7AyELERASu0BgUAMQQrsAYQsSwBK7QABQAmBCuxNwErsR4YERKwCzmwJhGyGgwbOTk5sDIStQ4TCSEVJCQXObEGERESsQM0OTmwLBGxKS85OQCxFQ4RErMLBgwRJBc5sCERsAM5sC8StBgAHiY0JBc5sCkRsBs5MDEBFAYHHgEVFAYjIic3FjMyNjU0JwYjIiY1NDcXDgEVFBYzMjYzJjU0NjMyFgc0JiMiBhUUFzYCgXlUCA5bQm0xKzA8ITMODhtgiVkyJCFfQAMJAjJtTFFcSzMqMDwrngF4TWcQDCsLOUZROEUgHBEhAn1YcUopHUI2OFQBSUpJaGJKLDk6MUw6IAAAAQBW//YDbgIuABoAggCyDQAAK7IBAAArtBcEACsEK7IXAQors0AXGQkrsAcvsRIE6QGwGy+wD9a0CgUAGwQrsAoQsQQBK7QVBQAbBCuyBBUKK7NABAEJK7AVELEYASu0AAUAMQQrsRwBK7EEChESswwNEhckFzkAsRcBERKxAgw5ObAHEbMECg8VJBc5MDEpATU2NTQmIyIGFRQXByY1NDYzMhYVFAczETMDbv5WgXpbXHeQI7SmfHqdT95QOkaNXHt9XqA2PUvJfKijfI0/Ad4AAAACAFn/8wPxAjIAKAA0AJUAshQAACuwAzOxHwTpsDIysC0vsQkE6bANL7QmBAA3BCsBsDUvsBfWtBwFADEEK7AcELEiASuxEQXpsBEQsQYBK7QwBQAxBCuwMBCxKQErtAAFADwEK7E2ASuxIhwRErIZFBo5OTmxKTARErQDCQ0mCyQXOQCxLR8RErYAEBEXHAYjJBc5sAkRsAs5sSYNERKwGjkwMSUUBiMiJjU0NjMyFyYjIgYdARQGIyImNTQ3FwYVFBYzMjY9ATQ2MzIWBzQnJiMiBhUUMzI2A/F7X1VlelYjGz9rSGByXm2Doip8W0hFM5Bfka1SDxlENlBwOUniZIt+XFd/B0poSHNecqJ3z1c8R5hVhVZWYF2Itq5fHg9NNpZTAAAAAAMAWf/8BEoCLQAjACkAMgDqALIBAAArsAwztBUEACsEK7AkMrAXL7AoM7EyBOmwIDKyMhcKK7NAMiIJK7AHL7QRBAArBCuwLS+0HQQANwQrAbAzL7AO1rQJBQAbBCuwCRCxBAErtBMFABsEK7IEEwors0AEAQkrsxoTBAgrtC8FABsEK7ATELEWASuwKjKxKQXpsB8ysCkQsSQBK7QABQAbBCuwABC0IgUAEQQrsCIvsTQBK7EECRESswsMEBEkFzmwGhGwFTmxFi8RErAdOQCxFQERErECCzk5sBcRswkOEwQkFzmxBzIRErEhJTk5sS0RERKxGi85OTAxKQE1NjU0JiIGFRQXByY1NDYyFhUUBzM1LgE1NDYzMh0BNhMzAzUOASMVAzQmIgYVFBYXBEr9KUxXdFZJJGqAroEg/GF/XD6avSgtShSCMlQvPCxaPSooVzhPTDhUIjo5d1R1dVRFJoIOaFc/XqR9DgEH/iDoIkSCAVcfMDciNkUGAAAAAAEAV//wBQcCMwAuAJgAsg0AACuyAwAAK7AXM7EnBOmwCS+wETOxIATpsBwyAbAvL7AZ1rQUBQAmBCuwFBCxDQErsQwF6bAMELEGASuxJAXpsCQQsSoBK7QABQAmBCuxMAErsQ0UERKyFhccOTk5sAwRsB45sAYSsCA5sSokERKyAywtOTk5ALEnDRESsBY5sAkRtgYAFBkeIyokFzmwIBKwLDkwMQEUBiMiJj0BNCMiFREjETQmIyIGFRQXByY1NDYzMhc2MzIWHQEUFjMyNjU0JzcWBQd1dGx3k3lWUD9MWoEtoYdvgDc0am+ESUJOTY0rrgEYhp+QdFqTif6iAV4/THxWp0I7Wcp4pExMe2plSl57YqJAN1QAAAAAAQBZ//cEewIuAC4AxgCyAgAAK7AcM7AQINYRtCYEACsEK7QRBAATBCu0DgQAEwQrsBYvsSEE6bAIL7QsBAA3BCsBsC8vsB7WtBkFABsEK7AZELETASu0JAUAGwQrshMkCiuzQBMQCSuwJBCxKQErtAsFADEEK7ILKQors0ALDwkrsAsQsQUBK7QABQA8BCuxMAErsRMZERKyGxwhOTk5sCQRsCY5sQspERKwJzmwBRGyAgMsOTk5ALEmDhESsQMbOTmwFhG3BQsAExkeJCkkFzkwMQEUByc2NTQmIyIGFRQWFxUhNTY1NCYjIgYVFBcHJjU0NjMyFhUUBzMmNTQ2MzIWBHu0IYJrU1dxQjD+XUhSOjlTRiFtgVRceR2tQaB4c54BDclLPj2ZWYB3WUqIEjEqH184TUo3VSU8N39TenRZSCJQg3mfqwAAAAABAGX/OANXAiAACQBUALIAAAArsAUztAMEACsEK7IAAwors0AACAkrsgMACiuzQAMBCSsBsAovsADWtAMFACYEK7ADELEIASu0BwUAJgQrsgcICiuzQAcFCSuxCwErADAxMxEzESEVIRUjNWVOAqT+tk4CIP4hQcjIAAAAAQBV/tQC5ALlAB0AnACyHAMAK7EDBOmwDS+xEwTpsAkvsQYE6bAXINYRsBYzsRgE6bAZMgGwHi+xHwErsDYauj879hkAFSsKDrAVELAawLELEfmwBcAFswYLBRMrswkLBRMrsBUQsxYVGhMrsxkVGhMrAwCzBQsVGi4uLi4BtwUGCQsVFhkaLi4uLi4uLi6wQBoAsRcTERKxDxA5ObEDBhESsQABOTkwMQEHJiMiBwM3FQcwAwYjIic3HgEzMjcTBzU3EzYzMgLkRxM8QQ0zXms5GYN1IUgDMBtADjhMWjQXhHYCdh9DU/7GBk4F/qmVcR4cJ1MBSQVNBAFKkwAAAAEAWv/zAfoCLQAXAGcAsgMAACuxCgTpsgoDCiuzQAoGCSuwDi+0FQQANwQrsg4VCiuzQA4SCSsBsBgvsAbWsBIytAcFACYEK7ARMrAHELEMASu0AAUAMQQrsRkBK7EMBxESsgMOFTk5OQCxDgoRErAAOTAxARQGIyImNTMUFjMyNTQjIgYVIz4BMzIWAfptbWBkTkMziYI6RE8CbllqbQEYg6J0ZjlX285PPFx2mgAAAf+TAAAAygMtABEATACyAQAAK7IEAwArsQ4E6QGwEi+wC9a0BwUAJgQrsAcQsQEBK7QABQAmBCuxEwErsQcLERKwCTmwARGxCA45OQCxBAERErEICzk5MDEzIxE0JyIGFBcjJjU0NjMyFhXKTU4hMAtQBlZGRFcCj1EBMUIbIRxFWFFDAAAAAAL/bwAAAMoDLAASABoAbwCyAQAAK7IFAwArsRAE6bIOAwArtBkKARANK7QZBAArBCsBsBsvsA3WtBcFABsEK7AXELETASu0BwUAGwQrsAcQsQEBK7QABQAmBCuxHAErsRMXERKwCjmwBxGxBRA5OQCxBRkRErIHDRU5OTkwMTMjETQmIxYVFAYjIiY1NDYzMhUnNCMiFRQzMspNMC0jPygsQWJJsMklJiYlAn0vNh8oKT5CLD9LqR4uLisAAgBI/tYBdAIuABYAHwBzALIJAAArtBoEAB8EK7IUAAArsAMvtB4EAB8EKwGwIC+wBta0HAUAGwQrsBwQsQsBK7QSBQAbBCuzFxILCCu0AAUAGwQrsSEBK7EcBhESsQ4POTmwCxGzAwkaHiQXObASErEUGTk5ALEaHhESsQAGOTkwMQUUBiMiJjU0NjM2NTQmIzceARUUBx4BBzQmIgYUFjMyAXRWQ0JRSDEpVDwKWnMqMTxEMUgyMCVWmUBRVUI3XH2cSYZGDpNntHUKUzcmNzRKNAADAEj+1gF0Ai4AFgAeACgAmACyCAAAK7QZBAAfBCuyFAAAK7ADL7QmBAAfBCuwIS+0HQQAEwQrsA4vtA8EADcEKwGwKS+wBda0IwUAGwQrsCMQsQoBK7QSBQAbBCuwEhCxHwErtAAFABsEK7EqASuxIwURErEODzk5sAoRtgMIGRsdISYkFzmwEhKyAhQXOTk5ALEdIRESswUAHyMkFzmxDggRErASOTAxBRQGIiY1NDYzNjU0LgEjNx4BFRQHHgEHJiMiBxYzMhcGIyInFBYzMjYBdFeEUUkwJR9DLQlZdScxPEsZNTwTGTI1JRREQhMxJScwmT9SVUI3XG2hNGFERwmXZblzClIQNjoaAiAcJjM1AAACACv+1AHDAiYAIAAqAIkAsAMvtCkEACsEK7AOMrAkL7QJBAAfBCsBsCsvsAbWtCYFABsEK7AmELEUASu0FwUAJgQrsBcQsSEBK7QMBQAbBCuwDBCxEAErtAAFABsEK7EsASuxFxQRErMDCSQpJBc5sQwhERKxDhI5ObAQEbEaGzk5sAASsBw5ALEkKRESswAMEAYkFzkwMQUUBiMiJjU0NjMyFhUUBzY1NCcmETUzFRQWFx4FBzQmIyIVFBYzMgHDh2VKYlFBOlAvanhrTDY5CSQQGQoJwCkjSiwgSmJdbVlHQlRXOkceHmpCgXMBD0VmgJJFCisTJR0qQSc2XSQ5AAAAAAMAK/7UAcMCJgAjAEQATwD9ALAnL7RNBAArBCuwMjKwES+wCjO0HQQAEwQrsCEyshEdCiuzQBEOCSuwSC+0LQQAHwQrAbBQL7Aq1rRKBQARBCuwShCxGgErtBQFABEEK7AUELE4ASu0OwUAJgQrsw47OAgrtA0FABEEK7MHOzgIK7QABQARBCuwOxCxRQErtDAFABEEK7AwELE0ASu0JAUAGwQrsVEBK7E4FBESshgXSDk5ObAOEbERHTk5sA0SsS1NOTmwBxG1AwoEISdHJBc5sUUAERKwNjmwMBGwMjmwNBKxPj85ObAkEbBAOQCxEU0REkAKAAcDFBgaKjBFSiQXObAdEbIfJDQ5OTkwMRcUBgcnPgE1NCYjIh0BIzU0IyIGFRQWFwcmNTQ2MzIXNjMyFjcUBiMiJjU0NjMyFhUUBzY1NCcmETUzFRQWFx4FBzQmIgYVFBYzMjb8FBAIBwsOCAYcCQgNDQYJJBkWDQoJDBcYx4dlSmJRQTpQL2p4a0w2OQkkEBkKCaw5Tjc+Iig2ixEjCiMCEgcKDApHRwoMCggSAyIVKBkkDQ0jEV1tWUdCVFc6Rx4eakKBcwEPRWaAkkUKKxMlHSpBKzIxLCI7MQAAAAIAWf/2AsoCLQAcACcAhQCyFAAAK7ACM7QmBAA3BCuwIC+0DgQAKwQrsAgvtBoEADcEKwGwKC+wF9axIwXpsCMQsR0BK7ERBemwERCxBQErtAAFADwEK7EpASuxIxcRErEKCzk5sB0RsQ4UOTmwERKxCBo5ObAFEbECAzk5ALEmFBESsAM5sCARtAUAERcLJBc5MDElFAcnNjU0JiMiBgc+ATMyFhUUBiMiJjU0NjMyFgU0JiMiBhUUFjI2AsqnKn6AZmKFBgtPL0poa1Fhaa+Mh6/+uTkqKzw9VDn9s1Q6QI1mg4JhISpjSE1ghm2MuKviKz49Kyo6OgAAAAMAVv/wAhcCLwAjACcALwCeALIDAAArtBsEADcEK7AqL7QhBAArBCuwDy+0JAQANwQrsBUvtAkEAEMEKwGwMC+wBtaxGAXpsBgQsR4BK7ASMrQsBQAmBCuwJjKwLBCxKAErsCQytAAFABsEK7AMMrExASuxLB4RErUJAxQVGxwkFzmwKBGxIQ85OQCxKhsRErIAHi45OTmxDyERErEGGDk5sRUkERKyEgwlOTk5MDElFAYjIiY1NDYzMhYVFAYjIiY1NDcnDgEVFBYXNyY1NDYzMhYmNCIUFzQjIhUUMzICF2tMfY2Pe01qQjQyRiEDSFVVSAMhRTM0QkpYWCwqKiyBQk+dgoGfUUQyPj4wKCQCAYBWV4ABAiQnMTw9vVZW8C4uLf//AFn/9gV8Ai0QJwbEArIAABAGBsQAAP///Rv/8wIYAi0QJga9HgAQBwbE/MIAAP///cz/8AIOAi8QJga9FAAQBwbF/XYAAP///Rv/8wLUAi4QJgbMAAAQBwbE/MIAAAAB/58CLQDbAukAEwA0ALADL7QNBABDBCsBsBQvsAXWtAoFABsEK7AKELEPASu0AAUAGwQrsQ8KERKxAwI5OQAwMRMUBiImNTQ3MwYVFBYyNjU0JzMW21yEXAFJAjJIMgFIAQLURGNjRBAFCA0mODgmDgcFAAEAOgJAANYC3AAKADUAsggDACu0AwQADQQrsggDACu0AwQADQQrAbALL7AG1rQABQANBCu0AAUADQQrsQwBKwAwMRMUBiMiJjQ2MzIW1isiIC8vICEsAo0gLS1ALy0AAAEAL//zAtQCLgAmAK4AsgMAACu0CQQAQwQrsgkDCiuzQAkGCSuwFS+wDTOxHwTpsCQyshUfCiuzQBUSCSsBsCcvsB3WtBgFACYEK7AYELESASuxEQXpswcREggrtAYFACYEK7AGL7QHBQAmBCuwERCxCwErsQAF6bEoASuxGB0RErAbObAGEbIVGh85OTmwEhKwBTmxEQcRErAhObALEbIJAyQ5OTkAsRUJERKyABodOTk5sB8RsCE5MDEBFAYjIiYnMxYzMjU0IyIGHQEHNTQjIgYVFBcjJjU0MzIXPgEzMhYC1JB+WnQETxNrvYkpOVhaOioESwfBUSgePj9ibgEahaJbTF7byDkqYgJZbkhLGCc1FNdDJx2fAAAABQBX/xkDYQIuADEAPQBJAFQAdgF1ALJlAAArsF4ztHAEABMEK7B0MrJuAAArsnYAACuwCy+xUATpsFgvsWFrMzO0WQQAEwQrtGoEABMEK7BML7EkBOmwHy+wKTO0RwQANwQrsDsysEEvsDUzsRkE6bAvMgGwdy+wFtaxRAXptCIFABsEK7BEELBOINYRtBAFADwEK7AQL7ROBQA8BCuwRBCxbQErtGcFABsEK7BnELE+Cyu0HAUAJgQrsBwQsWIBK7RhBQAbBCuwYRCxLAErtDgFABsEK7A4ELFcASu0VQUAGwQrsFUQsUoBK7AyMrEGBemwBhCwACDWEbQmBQAbBCuwJi+0AAUAGwQrsXgBK7FtThEStRMZH0FHEiQXObEcZxESs2Vqa3AkFzmxYWIRErQkTFALciQXObE4LBESs1hZXnQkFzmxSlURErUEKS81OwMkFzkAsWVZERK2EEpOBlVnbSQXObBwEbByObEkTBESswMSEwQkFzmxQUcRErUAFhwmLCIkFzkwMQEUBgcVFhUUDgIjIi4CNTQ3NS4BNTQ2MzIWFRQGIyImJxQhIDUOASMiJjU0NjMyFgc0JiMiBhUUFjMyNiU0JiMiBhUUFjMyNgE0ISAVFCEyPgInFAYjJzI2NTQjIh0BIzU0IyIVFBYXByY1NDYzMhc2MzIWA2FXRopCcHxGR3htPodMVGRYRFpWQSpECwE5AT0KRCxAU1lFVGVkMSclMjMkJzH+aTAmJTQzJiUxAZT+4P7pARcwXFw4YTsgFw0mPB1AIjkiEBlZSi8nGxslLUsBVFaGCQgYejVMKRISKE01ehgFDn9dX3leRUNcMSO2tiUvXkNGW30jJjAwJCU4NCcmMDAkJjc2/mxoaG4KFy0eHC0uEgkaDFRUDBoMEwMoFTMjJQ8PJQAAAAADAFn/HgS9Ai4APQBJAFQBEQCyHwAAK7ISAAArsC8ztEgEACsEK7BTMrIBAAArsAMvtAgEACsEK7BNL7QpBAArBCuwQi+0GAQAHwQrsCMvsBozsTUE6bA5MgGwVS+wMtaxUAXpsFAQsUsBK7EsBemwLBCxHwErtB4FACYEK7AeELEVASu0RQUAGwQrsEUQsT4BK7QPBQAbBCuwDxCxCwErtAAFABsEK7FWASuxUDIRErElJjk5sEsRsSkvOTmwLBKxIzU5ObEeHxESsDc5sUUVERKwOTmwPhG1AwgSBRoYJBc5sA8SsQ07OTkAsQgDERKwBTmwEhGwBjmxTUgREkAJCw8AFSwyPkUmJBc5sUIpERKxDUA5ObEjGBESsTc7OTkwMSUUBiMiJzcWMzI2NTQnFhUUBiMiJjU0NjMmIyIGFREjETQmIyIGBz4BMzIWFRQGIyImNTQ2MzIXNjMyFx4BBzQnJiMiBhUUFjMyJDQmIyIGFRQWMzIEvaiFVEQfOj9lf4MdXltUX3VeH2U+Tk9SQF58Bg1MMEpoa1FgaqaOhiongJ5JcYH2JgoQR1Q2MnP9vDkqKzw9Kit5kMsuPiujcsklOEhqgnBbY4c5SD3+oQFfPUiDXiIpYklOX4hrj7ZXV4ENpilYQQJiSjlNO1Y+PSsqOgAAAAAD/XH+zAAAAEUALgA5AD8A4gCyCgAAK7QzBAArBCuzGwozCCu0PAQAHwQrsAMvsCEztDgEAB8EK7AWL7AOM7QnBAAfBCuwKzKyFicKK7NAFhMJKwGwQC+wJNa0PgUAGwQrsD4QsToBK7QeBQAbBCuwHhCxEwErtBIFABsEK7ASELEGASu0NgUAGwQrsDYQsS8BK7QABQAbBCuxPiQRErAZObA6EbEbITk5sB4SsRYnOTmxEhMRErApObE2BhESsQ4rOTmwLxGyAwoMOTk5ALE4AxESsD45sDwRtQAGJB4vNiQXObAzErAZObEnFhESsCk5MDEVFAYjIiY1NDc2MzIXJiMiBh0BIzU0IyIGBzYzMhYVFAYjIiY1NDYzMhc2MzIXFgc0JyYjIgYVFDMyJTQjIhQyTEI1PiAmPwQGFEsaQURmK0ALGiUvP0EzPj5vWV4ZG2RYPTxACA8jICs6S/5fMjRmhUpkSjo+LDICHCwk4+ZNPioVQTAzRFpKW3o7Ojo5YSEVBjMhTDM8dAAD/ST+1AAKANkAPABHAE4BBwCwAy+0CAQAHwQrsBIvsC0ztEYEAB8EK7BOMrBKL7QnBAAfBCuwIi+wGjO0MwQAHwQrsDgyAbBPL7Aw1rRMBQAbBCuwTBCxSQErtCoFABsEK7AqELEfASu0HgUAGwQrsB4QsRUBK7RDBQARBCuwQxCxPQErtBAFABEEK7AQELELASu0AAUAEQQrsUwwERKwJTmwSRGxJy05ObAqErEiMzk5sR4fERKwNTmxQxURErIFGjg5OTmwPRG0BggDEhgkFzmwEBKxDjo5OQCxCAMRErAFObASEbAGObBGErEeHzk5sEoRQAkLEAAVMCo9Q0wkFzmwJxKxDiU5ObAiEbQYNTo/QCQXOTAxFxQGIyInNxYzMjY1NCYnFhUUIyImNTQ2NyYjIgYdASM1NCMiBgc2MzIWFRQGIyImNTQ2MzIXPgEzMhceAQc0JyMiBhUUFjMyBDQjIhUUMwpsVzUyGSQqPE4rIQ5wLz9FLhw2IS1GZC0+DBklMD5BMj4+bllTKBFBHIIaRVWtEwohMR4XOv51MjUzRl+HITUcZEQuTQ0eI51SNTdhBRgyIuToTz4tFUExM0VcSlx8Ph0gUwpxGTUlQCQcMgN2OjwAAQBN//ICrwIhABgAWACyEgAAK7QHBAA3BCuwAS+0FwQAQwQrAbAZL7AU1rQEBQAbBCuwBBCxCgErtA8FABsEK7EaASuxCgQRErIMERI5OTmwDxGwDTkAsQEHERKyDA8UOTk5MDEBISIGFRQWMzI2NTQnMxYVFAYiJjU0NjMhAq/+gEpVVklLVlBhMnnSe4NyAW0B2HhVVnt6V3BCTGZ3oqJ3e5sAAAAAAgAj/zYCtQIxABYAHgBpALIBAAArsQ8E6bAXMrINAAArsAkvtAYEACsEK7AbL7EUBOkBsB8vsAzWtAMFABsEK7ADELEQASu0HgUAJgQrsB4QsRcBK7QABQAmBCuxIAErsRceERKzCBMUByQXOQCxAQYRErAMOTAxIQUiFRQWOwEVIyImNTQ2OwE1NDYyFhUHNTQmIgYdAQK1/g5YMiaosz5XTztAg8CFS1qAWAE/ISRFTjw7T/Zjjoli/PhDYmRD9gAAAAEATf/2AvwCLQAaAHQAsg4AACuyAQAAK7EZBOmwBy+0FAQAQwQrAbAbL7AR1rQKBQAbBCuwChCxBAErtBcFABsEK7IXBAors0AXAAkrsgQXCiuzQAQBCSuxHAErsQQKERKzDQ4UGSQXOQCxGQERErECDTk5sAcRswQKERckFzkwMSkBNTY1NCYjIgYVFBYXBy4BNTQ2MzIWFRQHMwL8/rFzcFlYb1JDL01cnHd1kUvhOkaMXHx+XVJ5FzEikGJ7qKR6hz4AAAAAAQBV//IEBgItACkAnQCyFwAAK7IBAAArsAszsSgE6bAQL7AHM7QdBAArBCuwIzIBsCovsBrWtBMFABsEK7ATELEMASu0CwUAJgQrsAsQsQQBK7QmBQAbBCuyJgQKK7NAJgAJK7IEJgors0AEAQkrsSsBK7EMExESshYXHTk5ObALEbAgObAEErAjObAmEbAoOQCxKAERErECFjk5sBARtAQTGiAmJBc5MDEpATU2NTQmIyIGFREjETQmIyIGFRQWFwcuATU0NjMyFhc+ATMyFhUUBzMEBv6xc1hFOEpMRjFMY1U+NElah201VBQQYjple0TYOkWNU4VQOv6mAVo2WIBTUYMbNCaWYnanNCkoNal1b1YAAgBV//ACmgKuABcAIQCCALIDAAArsA0zsR8E6bAHL7QSBAA3BCuwFTKwEhCxGwTpAbAiL7AP1rQKBQAbBCuwChCxBgErsBIytBwFABsEK7AUMrAcELEYASu0AAUAJgQrsSMBK7EGChESsQwNOTmxGBwRErADOQCxHwMRErAMObAbEbIACg85OTmwBxKwCDkwMSUUBiMiJjURDgEVFBcHJjU0Njc1MxUeAQc0JicRFBYzMjYCmlVJRUxaeF80b6B2SW15S1BLJiMnK9Rain5XAR8FkmF+SDNgnn65BIKID7uHZowS/u40WWIAAAABAFD/KAOmArsAOgC2ALIjAAArsAIzsDIvsQ8E6bAVL7EWBOmwHS+0KAQAKwQrsAgvtDgEADcEKwGwOy+wNda0CwUAGwQrsAsQsSUBK7QgBQAbBCuwIBCxEgErsBoytC8FACYEK7ArMrAvELEFASu0AAUAGwQrsTwBK7EgJRESsCM5sBIRQAoIDxUWHSIoLTI4JBc5sQUvERKxAgM5OQCxFSMRErMDEiIvJBc5sBYRsS01OTmwHRK1BQsAICUrJBc5MDEBFAcnNjU0JiMiBhUUHgEzMjY1NCsBNTMyNjU0JiMiBhUUFwcmNTQ2MzIWFRQHFhUUBiMiJjU0EjMyFgOmVDpEwZqgyj+NZFh3aUBAMTpVP190MkA3nHxegE1MpXmywe/Ft+sBEp2CInCHnczcp2ypa2FRdE4/Mj1Nj2drdh2GgYCvcFl1ICOCb4n7wc8BCPEAAQBV/ycEvQIxADsArACyHgAAK7EUKTMzsAQvsQkE6bAiL7EQGTMztC8EAEMEK7E0OTIyAbA8L7As1rQlBQAmBCuwJRCxHgErtB0FACYEK7AdELEVASu0FAUAJgQrsBQQsQ0BK7QABQAbBCuxPQErsR4lERKyKCkvOTk5sB0RsDI5sBUSsgcGNDk5ObAUEbIJBDY5OTmwDRKwOTkAsQkEERKwBjmwHhGwBzmwIhK1DQAoLDI2JBc5MDElFA4BIyInNxYzMj4BNTQmIyIGFREjETQmIyIGFREjETQmIyIGFRQWFwcuATU0NjMyFhc2MzIXPgEzMhYEvV2tajQ5FCovVY5MWFgzQ01INDNLTEUyS1xNPjRJWodtNFYTI396KhZQNXaA33HJfhVGD2qmXHGYUjf+oQFrNElKM/6VAV81VH1WVIEaNCaWYneqNCdbWygzwgAAAAIAU/8nAqgCLQAjAC0AjQCyGwAAK7QtBAA3BCuwBC+xCQTpsCcvtBUEACsEK7APL7QhBABDBCsBsC4vsB7WsSoF6bAqELElASuxGAXpsBgQsQwBK7QABQAbBCuxLwErsSoeERKxERI5ObAlEbQECRUbBiQXObAYErEPITk5ALEJBBESsAY5sBsRsAc5sSctERK0AAwYHhIkFzkwMSUUDgEjIic3FjMyNjU0JiMiBgc+ATMyFhUUBiMiJjU0NjMyFgQ0JiMiBhUUFjICqGCvazU1FSksgq99aGF5BQpJLUdhYk9dYqSGhab+xDQoKTo5UuFyyn4WQgzcj3CWf2IhKmNHT1+Ia4y4v/hUPz4qKTsAAQBV/ycDQAItACUAmgCyGAAAK7IMAAArsSIE6bADL7EIBOmwEi+0HQQAKwQrAbAmL7Aa1rQVBQAbBCuwFRCxDwErtCAFABsEK7IPIAors0APDAkrsCAQsSMBK7ALMrQABQAmBCuxJwErsQ8VERK2AwgFFxgdIiQXOQCxCAMRErAFObAYEbAGObEiDBESsQ0XOTmwEhGzDxUaICQXObAdErEkJTk5MDEhFAYjIic3FjMyNjchNTY1NCYjIgYVFBcHJjU0NjMyFhUUBzMRMwNAwoctOBUqLV2KCv7Fc3NXWHGRKaebdnWRT9hLZHUVRQ5KQzpGjFyCg16oNjVMyHuopHqIPQHaAAAAAgBU//ADrQMCACcAMQCuALINAAArsgQAACuwGDOxLwTpsBEvsAgztB4EAEMEK7AiMrAeELAlINYRsSsE6QGwMi+wG9a0FAUAJgQrsBQQsQ0BK7QMBQAmBCuwDBCxBwErsCIytCwFABsEK7AkMrAsELEoASu0AAUAGwQrsTMBK7ENFBESshcYHjk5ObAMEbAgObEoLBESsAQ5ALEvDRESsBc5sCsRswAUGyAkFzmwERKwCTmxHiURErAhOTAxJRQOASMiJjURDgEVESMRNCYjIgYVFBYXBy4BNTQ2MzIXNjc1MxUeAQc0JicRFBYzMjYDrSJKMklJNj1LRjFLXUs9MklZh21kODJnSm15SlFLJCUoK9Q5ZkV9WAEfBEc6/qEBXzRRelVUgBo1JZdidqddWQPW3A+7h2WNEv7uPk9cAAABACz/JwTFAjQAKwB0ALIHAAArsAMzsRsE6bAkMrANL7ESBOkBsCwvsBXWtAoFADwEK7AXMrAKELEeASuxIQXpsCEQsScBK7QABQAmBCuxLQErsR4KERKwBzmwIRGwBTmwJxKyAykqOTk5ALESDRESsA85sAcRsBA5sBsSsAk5MDEBFAYjIicGIyInFRQGIyInNxYzMjY3ETMRFBYzMjY1ETMRFBYzMjY1NCc3FgTFiG93OjlxWj/Chy04FSotXYkKUk5FOUtUVTlLWX0oowEQeaRYWDIlZHUVRQ5KQwIl/q9GUU47AV7+ojdSeVelRztXAAAAAQBV/ycDdgIxAC4AiQCyFQAAK7AgM7AEL7EJBOmwGS+wEDO0JgQAQwQrsCwyAbAvL7Aj1rQcBQAmBCuwHBCxFQErtBQFACYEK7AUELENASu0AAUAGwQrsTABK7EVHBEStAcGHyAmJBc5sBQRsgkEKTk5ObANErAsOQCxCQQRErAGObAVEbAHObAZErQNAB8jKSQXOTAxJRQOASMiJzcWMzI+ATU0JiMiBhURIxE0JiMiBhUUFhcHLgE1NDYzMhYXPgEzMhYDdl2tajQ5FCovVY5MWFgzQ01EMktcTT40SVqHbTNWFBVRNHaA33HJfhVGD2qmXHGYUjf+oQFfNVR9VlSBGjQmlmJ3qjMnKDLCAAADAFn/8gUqAmIACAATAEsA+wCyJwAAK7AyM7IZAAArtAcEACsEK7IMAQArsUYE6bM8RgwIK7A4M7QiBABDBCuwKzK0HgIyDA0rsBQztB4EADcEK7A/MgGwTC+wNda0LgUAPAQrsC4QsScBK7QmBQAmBCuwJhCxHAErtAQFABsEK7AEELEAASuwHzK0FgUAMQQrsD8ysBYQsUMBK7QPBQAbBCuwDxCxCQErtEkFACYEK7FNASuxJy4RErIxMjg5OTmwJhGwOjmxBBwRErA8ObAAEbEZIjk5sQ9DERKwQDmwCRGwRjkAsQcnERKwMTmwAhGxGxw5ObAeErEuNTk5sCIRtQ8JETpDSSQXOTAxJTUjIhUUFjMyATQmIyIGFRQWMjYHIxUUBiMiJjQ2OwEuASMiBhURIxE0JiMiBhUUFhcHLgE1NDYzMhc2MzIWFzMuATU0NjMyFhUUBgNTL38hHm8BiTUnKTs5UjWmk2FSRk9tUzMKVkY6RE9MNE1jUUE2TGKTcnkrKHZpiRF5ISljR09fidAjWSY5AW0rPz4qKTs4iylZeF2UUEtjTD3+oQFfNlV9V1WAGzQkmWN5pllZjGsKSS1HYWFPXWIAAAAAAgA+ALADagIMABEAGQBdALIAAQArsQEE6bAML7QUBAAfBCuwGC+0BgQAHwQrAbAaL7AP1rQEBQAbBCuwBBCxFgErtAkFABsEK7EbASuxFgQRErIGDBI5OTkAsRgUERKwCTmwBhGxBA85OTAxARUFIhU2MzIWFRQGIyImNTQzBxQzMjU0IyIDav2CZB4oKT9CLD9LqEQkJiYkAgxOAloiPigsQmNJruwuLiwAAAMAV//yA4QDBwAJABIAQQDvALIoAAArsBYztAgEADcEK7AQMrI2AgArtDsEAEMEK7QDIig7DSu0AwQAKwQrtC4dKDsNK7EuBOkBsEIvsCvWsQYF6bAGELEAASu0JQUAJgQrsCUQsRkBK7QOBQAbBCuwDhCxCgErsRMF6bM+EwoIK7QzBQAmBCuwMy+0PgUAJgQrsUMBK7EGKxESsR8gOTmwABGxIig5ObEZJRESsh0uOTk5ObAOEbA4ObAzErYMEBYbMTY7JBc5sAoRsRFAOTkAsQMIERK2Cg4TGSAlKyQXObEdIhESsRsMOTmwLhGxMUA5ObA2ErMzODk+JBc5MDElNCYjIgYUFjI2JTQnBhUUFjI2NxQGIyImNTQ3JiMiBgc2MzIWFRQGIyImNTQ2MzIWFzY1NCYjIgcnNjMyFhUUBxYBZTMoKjIzUDQBy1x6O2I5VGpUU2ODEXanwQYZXUVZXkhTYuPRMH0XJC8gOTYvMnNHTS90nis/O1Y+PGiMUWR1QGdjP1+KimGLcgqGXEZgRkpnk2SPtw0LIS0iNzwvVlxNNjtiAAADAFf/8gQUAwcACQASAEwBGACyIgAAK7IwAAArsBYztAgEADcEK7AQMrJBAgArtEYEAEMEK7QDKjBGDSu0AwQAKwQrtDYlMEYNK7AdM7E2BOmwOjIBsE0vsDPWsQYF6bAGELEAASu0LQUAJgQrsC0QsSIBK7QhBQAxBCuwIRCxGQErtA4FABsEK7AOELEKASuxEwXps0kTCggrtD4FACYEK7A+L7RJBQAmBCuxTgErsQYzERKxJyg5ObAAEbEqMDk5sC0SsSU2OTmxISIRErA4ObAZEbBEObAOErIdOkM5OTmwPhG2DBAWGzxBRiQXObAKErERSzk5ALEDCBEStgoOExkoLTMkFzmxJSoRErIbDDg5OTmwNhGxPEs5ObBBErM+Q0RJJBc5MDElNCYjIgYUFjI2JTQnBhUUFjI2NxQGIyImNTQ3JiMiBhURIxE0IyIGBzYzMhYVFAYjIiY1NDYzMhc2MzIXNjU0JiMiByc2MzIWFRQHFgFlMygqMjNQNAJbXHo7YjlUalRTY4MRNTZHUKVUcwYZXUVZXkhTYqKGekE1bVAzJC8gOTYvMnNHTS90nis/O1Y+PGiMUWR1QGdjP1+KimGLcgpOOP6hAV+GiVlGYEZKZ5NkjLpNTRghLSI3PC9WXE02O2IAAAACAFn/8gR8AjEALAA1ALoAshMAACuwHjOyBQAAK7Q0BAArBCuwLy+wADO0CgQANwQrsCsysA4vsBcztCgEAEMEK7AkMgGwNi+wIda0GgUAPAQrsBoQsRMBK7QSBQAmBCuwEhCxCAErtDEFABsEK7AxELEtASuwCzK0AgUAMQQrsCsysTcBK7ETGhESsh0eJDk5ObASEbAmObExCBESsCg5sC0RsQUOOTkAsTQTERKwHTmwLxGxBwg5ObAKErEaITk5sA4RsCY5MDElIxUUBiMiJjQ2OwEuASMiBhURIxE0JiMiBhUUFhcHLgE1NDYzMhc2MzIWFzMFNSMiFRQWMzIEfNlhUkZPbVMzClZGOkRPTDRNY1FBNkxik3J5Kyh2aYkR2f7XL38hHm/zKVl4XZRQS2NMPf6hAV82VX1XVYAbNCSZY3mmWVmMa2ojWSY5AAADAFf/8gV4AwcARQBOAFgBNwCyFwAAK7AOM7IlAAArsAMztFcEADcEK7BMMrI6AgArtD8EAEMEK7RSHyU/DSu0UgQAKwQrtCsaJT8NK7EKEjMzsSsE6bEvMzIyAbBZL7Ao1rFVBemwVRCxTwErtCIFACYEK7AiELEXASuxFgXpsBYQsQ8BK7QOBQAxBCuwDhCxBgErtEoFABsEK7BKELFGASuxAAXps0IARggrtDcFACYEK7A3L7RCBQAmBCuxWgErsVUoERKxHB05ObBPEbEfJTk5sCISsRorOTmxFhcRErAtObAPEbAvObAOErAxObAGEbA9ObBKErIKMzw5OTmwNxG2AzUIOj9ITCQXObBGErFETTk5ALFSVxEStgYAIihGSh0kFzmxGh8RErMILTFIJBc5sCsRsTVEOTmwOhKzNzw9QiQXOTAxJRQGIyImNTQ3JiMiBhURIxE0JiIGFREjETQjIgYHNjMyFhUUBiMiJjU0NjMyFzYzMhc2MzIXNjU0JiMiByc2MzIWFRQHFgc0JwYVFBYyNiU0JiMiBhQWMjYFeGpUU2ODETU2R1BNeEhXpVRzBhldRVleSFNiooZ6QS+EezI1cVAzJC8gOTYvMnNHTS90VFx6O2I5/EEzKCoyM1A03F+KimGLcgpOOP6hAV87S0o8/qEBX4aJWUZgRkpnk2SMuk1NTU0YIS0iNzwvVlxNNjtiroxRZHVAZ2MBKz87Vj48AAACAFn/8gPiAwMANgBAAOAAsg8AACuyAwAAK7AaM7Q+BAA3BCuwEy+wCjOxIATpsCQysCsvtDAEADcEKwGwQS+wHda0FgUAPAQrsBYQsQ8BK7QOBQAmBCuwDhCxBgErtDsFACYEK7A7ELE3ASu0AAUAPAQrszMANwgrtCgFACYEK7AoL7QzBQAmBCuxQgErsQ8WERKyGRogOTk5sA4RsCI5sAYSsC45sDsRsgokLTk5ObAoErYDJggrMDk+JBc5sDcRsDU5ALE+DxESsBk5sBMRtQAGFh0iOSQXObAgErEmNTk5sCsRsygtLjMkFzkwMSUUBiMiJjU0NyYjIgYVESMRNCYjIgYVFBYXBy4BNTQ2MzIXNjMyFzY1NCYjIgcnNjMyFhUUBxYHNCcGFRQWMzI2A+JpU1RlhBVBMEFPSzVOYlFBNk1hknNxMzNzTDkkLx88Ni42cEdMLXNSXng5MzE5216KiWCKcwxSNP6hAV82UHlWVYAbNCaXY3ilTk4aISwhODotVVpMNzpiropQYnZBY2IAAAIAWf/zArwDAwAnADEAugCyAwAAK7AQM7QvBAA3BCuwCi+xFQTpsBwvtCEEADcEKwGwMi+wEta0DQUAGwQrsA0QsQYBK7QsBQAmBCuwLBCxKAErtAAFADEEK7MkACgIK7QZBQAxBCuwGS+0JAUAMQQrsTMBK7EGDRESsg8QHzk5ObAsEbIKFR45OTmwGRK2AxcIHCEqLyQXObAoEbAmOQCxLwMRErAPObAKEbQABg0SKiQXObAVErEXJjk5sBwRsxkeHyQkFzkwMSUUBiMiJjU0NyYjIgYVFBcHJjU0NjMyFzY1NCYjIgcnNjMyFhUUBxYHNCcGFRQWMzI2ArxkU1FigRMwaoNkN3epjEc5Iy4eOzMuM25GUTNuUFpzNjAxNttgiIpfi3IMkW53SzBflpC2GiEsITg5LFVcSi1EYa+KUGF3QWNhAAADAFf/8gRaAwMAPABSAFsBAwCyAwAAK7EVIjMztFAEADcEK7BZMrAcL7ANM7QnBAA3BCuwKzKwMi+0NwQANwQrAbBcL7Ak1rQfBQAmBCuwHxCxGAErtFcFACYEK7BXELFTASuxEgXpsBIQsQYBK7RNBQAmBCuwTRCxPQErtAAFADwEK7M5AD0IK7QvBQA8BCuwLy+0OQUAPAQrsV0BK7EYHxESsSEiOTmwVxGxHCc5ObBTErMVDykaJBc5sBIRsCs5sAYSsQ01OTmwTRGwNDmwLxK2Ay0LMjdCUCQXObA9EbA7OQCxUAMRErAhObAcEUALAAYSGB8kO0JTVVckFzmwJxKxKS05ObAyEbMvNDU5JBc5MDElFAYjIiY1ND4CNyYjIgceARUUBiMiJjU0NyYjIgYVFBcHJjU0NjMyFzYzMhc2NTQmIyIHJzYzMhUUBxYHNC4CJw4JFRQWMzI2JTQnBhUUMzI2BFppU1RkEi8gJipfUT8vS3JRWml8Lx9ZenAwjLSGTzBKcHxUKSYhOjYvNnCSNXpSBxsYHwQgCRoIFAYMBAQ5MzE5/nJzcXUzPNteiolgKD8+ICQhEySSRliMgWOWZhOHXJhLLly8h5wpLSsjNyU2Oi1VqzlHbY8qNC0aHQQbBxkJFw4XFRkOQWNiO39WUIWfXwACAFn/8wPsAwMAMwA9AMwAsgMAACuwEDOwCi+xIQTpsBUysCgvtC0EADcEKwGwPi+wE9a0GAUAMQQrsBgQsR0BK7QNBQAxBCuwDRCxBgErtDkFACYEK7A5ELE0ASu0AAUAPAQrszAANAgrtCUFACYEK7AlL7QwBQAmBCuxPwErsR0YERKyFRAWOTk5sQYNERKwKzmwORGyCiEqOTk5sCUStgMjCCgtNzskFzmwNBGxMjw5OQCxCgMRErYAExgaHjc7JBc5sCERshYjMjk5ObAoErMlKiswJBc5MDElFAYjIiY1NDcmIyIdARQGIyImNTQ3FwYVFBYyNj0BNDYzMhc2NTQmIyIHJzYzMhYVFAcWBzQmJwYVFBYyNgPsZlVUY4QZLaR+X2xypjGHSJJAjWRIPSMtHzk8KzZvR0wtcVInM3s6ZDfbYIeIYHx5FNs6X36cfdFVMUOnXHxXXFFkiiEjLyE4QTRVWU09OmWlT1QuZmlAY2EAAAAABQBZ//IDvQMDAC0AOgBCAEoAVgEBALILAAArsQMHMzO0VAQANwQrsThHMjKwTy+xMEMzM7QQBABDBCuxLDsyMrA/L7QTBABDBCuwHy+0JAQANwQrAbBXL7AO1rRRBQAbBCuwURCxSwErsRBOMjK0RQUAGwQrsEEysEUQsUoBK7A7MrQxBQA8BCuwMRCxLgErtAAFABsEK7AAELAnINYRtBwFADEEK7AcL7QnBQAxBCuxWAErsUtRERKwCzmwRRGwCTmwShKzEyEHIiQXObAxEbIWBTU5OTmwHBK2GQMfJCosOCQXObAuEbApOQCxT1QRErMACQ4FJBc5sT8QERKxFik5ObATEbAZObAfErMcISInJBc5MDElFAYjIicGIyInBiMiJjU0MzQ2MzIWFz4CNzY1NCYjIgcnNjMyFhUUBw4BBzIHNCsBFAcGFRQWMzI2JzU0JiIGHQEXIxUUMzI2NQU0JjUjIhUUFjMyNgO9UkdjGCd5dicYYkZT6WlcRG0QDCgkAigzIkBDKTl5S1RCPiIN0kd9HwcHLCQpMfBFbEb5+X85Qf6/BSZ8LykjLKNOY1FRUVFjTqlkf0s3DyoiAzEmIjdDNlVaTDtDPS0pqF8DNCgQJjY/1RM4T1A3E0kVuF5aWg1EHl8tPzUAAQA8AAACDwLQACgAXACyAwAAK7QOBAAfBCsBsCkvsAbWtAsFADEEK7ALELEbASu0IAUAPAQrsCAQsRMBK7QABQAxBCuxKgErsQsGERKwCDmwGxGwCTmwIBKwGDmwExGyDgMlOTk5ADAxARQGIyImNTQ3MwYVFBYzMj4CNTQuBTU0NzMGFRQXHgUCD3Z1Y4UXUBdQSC0/IQ4eMDo6MB4DUAEJCTE5PzIhARV4nXtiMDMxMElaJUJHKzROLiUjKEMsFhYNGiUTFyshMDdaAAAAAAIAPAAAAjAC0AAXACMAjQCyAwAAK7QhBAAfBCuwGy+0CQQAHwQrsAsvtBMEAB8EK7QQBAASBCsBsCQvsAbWtB4FADEEK7MPHgYIK7QQBQAxBCuwHhCxCgErtBQFADEEK7QVBQAbBCuwFBCxGAErtAAFADEEK7ElASuxChARErEDITk5sBURsBs5ALEbIRESsQAGOTmwCRGwFTkwMSUUBiMiJjU0NjM1IyImPQEzFBY7AQceAQc0JiMiBhUUFjMyNgIwlGtlkJBunRUgUAUKwwdLYlBXSEprXEtKY9dob3FjX3G5EhNOJRL5EG5RR1BKR0pRTQACADwAAAJGAuQAJwAzAI0AsgMAACu0MQQAHwQrsh0DACu0FgQAHwQrsxoDHQgrAbA0L7AG1rQuBQAxBCuwGiDWEbQZBQAxBCuwLhCxEQErtB8FABsEK7AfELEoASu0AAUAMQQrsTUBK7ERGREStQ4DHB0rMSQXObAfEbAiObAoErAkOQCxGjERErQGDwAiKyQXObAWEbERHzk5MDElFAYjIiY1ND4GNzY1NC4CIyIGFSM+ATIWFRQGFR4EBzQmIyIGFRQWMzI2AkaWbWmeFB0vKDYhLQQYBQ8lHTEsUAFkmE4EBScrKxxQXEtRcmVIUG3manx+ZyM7KiQVEwgJASYvHicsF1Q+YmxmTR1ADwcYHixJMEthXk9IXlgAAAIAPAAUAvMC5AAyAD4AqgCyLAMAK7AwM7QRBAAfBCuwNjKwJC+xJQTpsiQlCiuzQCQYCSuwJRC0IgQANwQrsAMvtDwEAB8EKwGwPy+wKda0FAUAMQQrsBQQsTMBK7QABQAxBCuzGAAzCCuxGQXpsBkvsRgF6bFAASuxFCkRErEkJTk5sBkRQAkDFiImLDA2OTwkFzkAsSIkERKwHzmwJRGwFzmwAxKwFjmxETwRErQKABQpLiQXOTAxARQGIyIuAicuByMiBhUUFwQXIy4HIyIHNTMuATU0NjMyFzYzMhYHNCYjIgYVFBYzMjYC83BYL00zHwUBBAMGCA0SGRA4NnYBnShWBB80N0w8UCwfKz9dOT5mV1k3PWpXbFA+Oj1FQDxAPgIOWXMjO0kpCCoQIA4WCQdgQKFcFuEeMiIaDwkEAQlQMIlMWYJOTn5UPVlaPj1VUgABADwAAAIIAuQAIgB9ALICAAArtA0EAB8EK7IfAwArtBQEAB8EKwGwIy+wHNa0FwUAJgQrsBcQsAog1hG0BQUAMQQrsAUvtAoFADEEK7AXELEQASu0AAUAMQQrsSQBK7EcBRESsAc5sRcKERKwCDmwEBGzDQIUHyQXOQCxFA0RErMFBxkcJBc5MDElFCMiJjU0NzMGFRQWMzI2NRE0JiMiBhUUFyMmNTQ2MzIWFQII2W+EDFAMUUxKRUc7REUDUAJ5Xlp5+fmCbyApKSFOZl1MAUo6P01AEhMOHl1lXlcAAAEAPAAAAgMC5AAlAJsAsgMAACu0DgQAHwQrsh8DACu0GQQAHwQrshkfCiuzQBkcCSu0FBMDHw0rtBQEAB8EKwGwJi+wBta0CwUAMQQrsBwg1hG0GwUAMQQrsAsQsRABK7AWMrQABQAxBCuwIjKxJwErsRwGERKwCDmxGwsRErAJObAQEbQOAxMfJCQXOQCxEw4RErIABgg5OTmwFBGwJDmwGRKwIjkwMSUUBiMiJjU0NzMGFRQWMzI1NCYjNTI2NCYjIhUjNDYzMhYVFAcWAgN0aWaEEFAQUEiPNEQ8PEM6jlBzbVd0W1vvb4BxZDUtMCxJVqlIUTwydEiwbn5lVmMpIgAAAwA8AAAC4wLkAB4AKQA0AQAAsgMAACu0MgQAHwQrshQDACu0IgQAHwQrtBwtAxQNK7QcBAAfBCu0KA4DFA0rtCgEAB8EKwGwNS+wEda0JQUAMQQrsCUQsQYBK7QvBQAxBCuwGjKzHy8GCCu0FwUAMQQrsC8QsSoBK7QABQAxBCuxNgErsDYauj4Z8IIAFSsKBLAaLg6wGcCxCQz5sAzAswoJDBMrswsJDBMrsgoJDCCKIIojBg4REjmwCzkAtQwZGgkKCy4uLi4uLgG0DBkJCgsuLi4uLrBAGgGxBiURErMOFCInJBc5sB8RsCg5sSoXERKzAxwtMiQXOQCxLTIRErEABjk5sSIoERKxERc5OTAxJRQGIyImNTQ+AzcGIyImNTQ2MzIWFRQPATYzMhYBNCYjIgYVFBYyNgE0JiIGFRQWMzI2AuOCZGd7BA0GFQEtQEJdb0xHZwowQ2JYe/5yOSkqPTpaNQE+UIRUU0FEUOJkfnpnFy08GU0FJ1lBSltZRh4jpUZsARQpMjoqLTY+/sJBR1JCQVhgAAAAAAIAUAAAAy0C5AAdACkAgACyDwAAK7QoBAAfBCuyGgMAK7AWM7QIBAAfBCuwITIBsCovsBLWtCUFADEEK7AlELEeASu0DAUAMQQrsAwQsQUBK7QABQAxBCuxKwErsR4lERKxFg85ObAMEbAYObAFErEDGjk5sAARsAI5ALEoDxESsQMCOTmwCBGxDBg5OTAxJRQHIzY1ETQjIgYVERQGIyImPQE0NjMyFzYzMhYVARE0JiIGFREUFjI2Ay0xUDFcNDN9aG92eG1uRixyV0/+nU6OTk6OTv6LX3hjATWESDb+ymuJhHD8boZaWm5a/sQBJElbXEj+3ElbXAAAAAEAPAAUAjIC5AAfAD4AshsDACu0CgQAHwQrAbAgL7AW1rQPBQAxBCuwDxCxBQErtAAFADEEK7EhASuxBQ8RErQCAxITGyQXOQAwMQEUByM2NTQuAiMiDgIVFBYXIy4BNTQ+AjMyHgICMlZRVxAkRzAxRiQQMSZQJDMcOmRBQmQ5HAGks93HyS1UUjExUlQtW9xZVuRWPm5dNzddbgAAAAABADwAAAIFAuQAJAB9ALIDAAArtA4EAB8EK7IdAwArtBwEAB8EK7QYFQMdDSu0GAQAHwQrAbAlL7AG1rQLBQAxBCuwCxCxEAErsBoytAAFADEEK7AgMrEmASuxCwYRErAIObAQEbUDCRUcHSIkFzkAsRUOERKyAAYIOTk5sBgRsCI5sBwSsCA5MDElFAYjIiY1NDczBhUUFjMyNTQuAiM1FjMyNTQnNR4BFRQHHgECBXZpZ4McUBxRR5EIFjAjBw1cQURNUDAh726BcGVJODhDSFepIzMyGjwBcXIDPAphRmMsGVwAAAAAAQA8ABQDbwLkAEQAywCyOgMAK7E+QjMztBcEAB8EK7EIEDIysDAvtDQEAB8EKwGwRS+wNta0HAUAMQQrsBwQsRQBK7QTBQAbBCuwExCxDQErtAwFABsEK7AMELEsASu0KwUAMQQrsCsQsQUBK7QABQAxBCuxRgErsRw2ERKxMjM5ObAUEbIwNDo5OTmwExKwPDmwDRGxJD45ObAMErBAObAsEbAIObArErIDKkI5OTmxAAURErACOQCxNDARErAkObAXEbUAAgwTHDYkFzmwOhKxPEA5OTAxARQHIzY1NCYjIgYdASM1NCMiHQEjNTQjIg4CFRQeARceAxceBBcjJicmISIHNTMmNTQ+ATMyFzYzMhc2MzIWA28vUTAvMCwyPFhbPE8fKBAFGT8wFj0hXAgyRVEyJgRQCmh8/uk1NHOJH1A8RikvTEgxL1tIUwIyTFpXUTJCOS13d2Zmd3dmHjgtITRaThEIDAUKAQYOHy1MM2gjKgM8TrE6Ykc7Ozs7aQAAAAIAPAAAAgoC5AAZACUAfACyAwAAK7QjBAAfBCuyFgMAK7QPBAAfBCuyDxYKK7NADxMJK7QJHQMWDSu0CQQAHwQrAbAmL7AG1rQgBQAxBCuwEyDWEbQSBQAxBCuwIBCxGgErsAsytAAFADEEK7EnASuxGhIRErQJAxYdIyQXOQCxHSMRErEGCzk5MDElFAYjIiY1NDYzMhc1NCYjIgYVIzQ2MzIWFQM0JiMiBhUUFjMyNgIKem1jhIVgWUBAP0pOUH1tWnNQVz5BWFdAQlXzcoFzYV53PqNBWWVMbYByWv7DPlRaQUBWXAACAFAAAAIfAuQAHAAoAIgAsgMAACu0JgQAHwQrsg8DACu0GiADDw0rtBoEAB8EK7ENDxAgwC+0EgQAQwQrsAog1hG0FQQAHwQrAbApL7AG1rQYBQAmBCuwIzKwGBCxHQErtAAFADEEK7EqASuxHRgRErQKDRIDGiQXObAAEbEPEDk5ALEgJhESsQAYOTmxFRIRErAQOTAxJRQGIyImNQM0NjMyFjMyNxUGIyImIyIdATYzMhYHNCYjIgYVFBYzMjYCH4RjZ4ABUGcVVBU7QCAtHnYeYT9lXH9QWEE/VlNEQFfUYXN5ZgFDZUkIHFAVFVvOPnpdQVpTP0VaVgABAFAAFALGAuQAIgBoALIcAwArsCAztBEEAB8EK7AIMgGwIy+wGda0FAUAMQQrsBQQsQ0BK7QMBQAxBCuwDBCxBQErtAAFADEEK7EkASuxFBkRErAXObANEbEWHDk5sAwSsB45sAURsQMgOTmwABKwAjkAMDElFAcjNjURNCMiBh0BIzU0JiMiFREUFyMmNRE0MzIXNjMyFQLGMVAxXDM0UDQzXDFQMbBYMy9kqPSCXnliATWESTXR0TVJhP7LYnleggEoyExMyAAAAAABADwAAAH7AtAALgCHALIDAAArtA4EAB8EK7AWL7QXBAAfBCsBsC8vsAbWtAsFADEEK7ALELEgASu0IwUAPAQrsCMQsREBK7AaMrQABQAxBCuwKjKyEQAKK7NAERcJK7EwASuxCwYRErAIObAgEbAJObERIxEStA4DHSYsJBc5ALEWDhESsgYACDk5ObAXEbAsOTAxJRQGIyImNTQ3MwYVFBYzMjY1NC4CIzUyNjU0LgM1NDczFB4EFRQHHgEB+3tcZYMIUAhTQ0FIFC8vKGA6OFFROAJQKD1GPShTKyi+WmRrYh4eGyNCTU1BKDEXBjwWMBoqIidCLAcMJzMVGRk/L0sfElQAAAABAB4AAAIfAtAALgCtALIDAAArtA4EAB8EK7AbL7QlBAAfBCuwKi+0KwQAHwQrAbAvL7AG1rQLBQAxBCuzIwsGCCu0HgUAMQQrsB4vtCMFADEEK7ALELEoASu0FwUAMQQrsBcQsRIBK7QABQAxBCuxMAErsSMGERKwCDmxKAsRErQJGyUqKyQXObAXEbIOAxU5OTmwEhKwLTkAsRsOERKxBgg5ObEqJRESsh4XIDk5ObArEbEVEzk5MDElFAYjIiY1NDczBhUUFjMyNzY1EQYHFhUUDgEjIiY1NDczBhUUMzI2NTQnNTY3MwIfc2lqhgxQDFJLNS0tOGI3O0ooQl8CUAJWIjYvtitR5Wl8hmsZMCkhTGgjJGIBlh8PGDkpOBVBPxsNChVNISAwDDwNSAAAAQA8ABQC4wLQADkAigCwFy+wCDO0MgQAHwQrsDcyAbA6L7Ag1rQaBQAxBCuwGhCxEwErtAwFACYEK7AMELEoASu0KQUAMQQrsCkQsQUBK7QABQAxBCuxOwErsRogERKwHjmwExGyHTAyOTk5sAwSsS01OTmwKBGwJTmwKRKyCAM3OTk5sQAFERKwAjkAsTIXERKwMDkwMSUUByM2NTQmIyIHBhUUFhUjNDY1NCcmIyIGFRQWFyMmNTQ2Nz4BNzY3MxQHDgMHNjMyFhc2MzIWAuNBU0Q0ODAiJQFQAR8eLjI5KyRaRXt6CI4fHAtQTh6KaWALLUEqShg9Vlds3mtfVW87VSIjTAggCAknC0YhH0s0N3QqbWyApzYDNBcVI1goDywjSzIvKyRPbgAAAQBQAAACHQLQABcAYQCyAwAAK7QKBAAfBCuyCgMKK7NACgcJKwGwGC+wBda0CAUAMQQrsAgQsRIBK7QTBQAxBCuwExCxDQErtAAFADEEK7EZASuxEggRErEDCjk5sBMRsBA5sQANERKwFjkAMDElFAYjIjURMxEUMzI2NTQuAiczFB4CAh2KYuFQlERVGR4bAVAaHxrQYHDpAef+Ga1WRCQ4HSsZGikaOwAAAAMAPAAAAtwC5AAyAD4ASgDcALIGAAArtBQEAB8EK7IrAwArtDYEAB8EK7QfSAYrDSu0HwQAHwQrtDxCBisNK7Q8BAATBCuwMDIBsEsvsAzWtBEFADEEK7ARELEoASu0OQUAGwQrsEUysDkQtCIFADEEK7AiL7A5ELE/ASuwMzK0HAUAMQQrsC4ysBwQsRcBK7QABQAxBCuxTAErsREMERKwDjmwIhGwDzmxPzkRErYGHxQrNiU8JBc5sBwRsRowOTkAsUgfERKyABEMOTk5sEIRsxccIhokFzmwPBKyDyUOOTk5sDYRsS4oOTkwMQEUDgMjIi4DNTQ3MwYVFBYzMjY1NCYnFhUUBiMiJjU0NjcuATU0NjMyFhUUBzIWJzQmIyIGFRQWMzI2BzQmIyIGFRQWMzI2AtwmQFhgNTFeV0AnT1BPlHB1h0lCNGU9QmM5LCkzXUVCVjxqffMvJicuMiYlLQQpKScuLyYjLwENOFw9KhITKjtZNYdZXn1qZXl0RFgJJ0I6QkVALUMMCT8qQ0VHQT4hheImLjEnJTE1wis3NSclLysAAAABABQAAAKEAuQAPAC+ALIEAAArtA8EAB8EK7I0AwArsDkztB4EAB8EK7AWMrQuJAQ0DSu0LgQAHwQrAbA9L7An1rQsBQAxBCuwLBCxBwErtAwFADEEK7AMELEbASu0GgUAMQQrsBoQsRIBK7QABQAxBCuxPgErsQcsERKxJC45ObAMEbIJITE5OTmwGxKyCh40OTk5sBoRsDc5sBISsg8EOTk5OQCxJA8RErMHCRobJBc5sC4RsCE5sB4SsDc5sDQRsycpLDEkFzkwMSUUBwYjIiY1NDczBhUUFjMyNjURNCYjIgYdASM1NCMiDgMjIiY1NDczBhUUMzI+AzMyFhc2MzIWFQKEJymGb4QMUAxRTElDIC0iKlAdChcZHzMfNDsDUAMqDx0ZHCUWGigJK1o+TPlaTlGCbyApKSFOZl5LAV0xNS4ih5k+FiAfFkE0Dw8QEDcWHyAWJBo+Tj4AAAAAAgA8AAADEwLkADcAQwDfALIIAAArtBQEAB8EK7IxAwArsDUztDsEAB8EK7AkMrRBLAgxDSu0QQQAHwQrsBwg1hG0HQQANwQrAbBEL7Av1rQ+BQAxBCuwPhCxDAErtBEFADEEK7ARELE4ASu0KQUAMQQrsCkQsRcBK7QFBQAxBCuyFwUKK7NAFx0JK7AXELAhINYRtAAFADEEK7FFASuxEQwRErQOLDE7QSQXObA4EbAPObApErEnMzk5sBcRtAgUAyQ1JBc5ALEsFBESswUMDhckFzmxQRwRErADObE7HREStgApLi8zOD4kFzkwMQEUBgcWFRQGIyIuATU0NzMGFRQWMzI2NTQuASsBNTMyNjU0JiMiBgcWFRQGIyImNDYzMhc2MzIWBTQmIyIGFRQWMzI2AxNBOG+bcER2VwdUC2hTWGkPLSQ8OS8+PjAmPg0GelVbhH5aZUM8bUVp/odMNjtRSDY8VAI9PFoPK4dteSVfRjQZHxZRVVtXJDksRlAwLzwmIhsdVGdesGlOTmJZNklIOzZGRgAAAQA8AAACBwLQAB4AfACyAwAAK7QNBAAfBCuwEy+0GgQAHwQrshMaCiuzQBMXCSsBsB8vsAXWtAoFADEEK7MXCgUIK7QWBQAxBCuwChCxDwErsBwytAAFADEEK7EgASuxFwURErAHObEWChESsAg5sA8RswMCDRokFzkAsRMNERKyBQccOTk5MDElFAYiJjU0NzMGFRQWMzI9ATQmIyIGFSM0NjMyFzUzAgdx1oQLUAtSSo9WNjM8UGhPXzVQ7G1/f2siJCQjS2K3pjQ+PzNOYEnSAAABADwAFALwAuQANQC0ALIvAwArsDMztBUEAB8EK7AIMrAmL7QbBAAfBCuwKjKyJhsKK7NAJiEJKwGwNi+wLNa0GAUAMQQrsBgQsQ4BK7QNBQAxBCuwDRCxBQErtAAFADEEK7MgAAUIK7QhBQAxBCuwIS+0IAUAMQQrsTcBK7EYLBESsSgpOTmwDhG0FRsmKi8kFzmwDRKwMTmwIRGxCDM5ObAFErADObEAIBESsAI5ALEVGxEStQACDSksMSQXOTAxARQHIzY1NCYjIgcGHQEjNDY1NCcmIyIGFRQWFx4DFyMuAyMiBzUXJjU0NjMyFzYzMhYC8DVJLjc5LyEgUAIlJCc5PUxDQnp8UglQCExuaTRzQXGAaFxiNjtkUWgCLGNfYU88UiQlLG8HMg9nGxpjPU6HKgMaNGJCNE0nEQtQB2eTXoFRUWcAAQA8AAACCwLQACcAeACyAgAAK7QNBAAfBCuwEy+0HgQAHwQrAbAoL7AF1rQKBQAxBCuzFgoFCCu0GwUAMQQrsAoQsRABK7AjMrQABQAxBCuxKQErsRYFERKwBzmxGwoRErEIGDk5sBARtAINExkeJBc5ALETDRESsQUHOTmwHhGwETkwMSUUIyImNTQ3MwYVFBYzMjY9AQYjIiY1NDczBhUUFjMyNz4BNTQmNTMCC+ZpgA9QD1RMSkVBXk5kI1AjSTInHCkcAlDv73hoKjAxH05gXUz1Ol9NREBBSDE6ERZJNA02DQAAAAIAHgAAAj0C5AAiAC0AqACyAwAAK7QsBAAfBCuyGwMAK7AfM7QVBAAfBCuwDjKyFRsKK7NAFRIJK7QJJgMbDSu0CQQAHwQrAbAuL7AG1rQpBQAxBCuwKRCxEgErtBEFADEEK7ARELEjASuwCzK0AAUAMQQrsS8BK7EpBhESsBU5sBIRsBs5sBESsR0rOTmwIxG0AwkfJiwkFzkAsSYsERKxBgs5ObEVCRESsRgdOTmwGxGwGTkwMSUUBiMiJjU0NjMyFzU0IyIGFSM0JiMiBgc1NjMyFzYzMhYVAzQmIyIGFRQWMjYCPYJ6Z46SaWJEWD8hUBwxI0EWNklPJi1dUk9QYkdKXmGQYPx6gmxkZm490XBJXmBHLyJaMzw8YlT+pUZPUEhGTlAAAQBQABQCEgLkACkAhwCyEQMAK7QiBAAfBCuyGgEAK7QXBAATBCuwCC+0JwQAHwQrAbAqL7AN1rQMBQAxBCuwJDKwDBCxBQErtAAFADEEK7MVAAUIK7QeBQAxBCuwHi+0FQUAMQQrsSsBK7EeDBEStQgDERcZJyQXObEVBRESsAI5ALEnCBESsCU5sSIaERKwFTkwMSUUByM2NTQmIyIGHQEjETQ2MzIXFhUUIyInNTI3NjU0LgEjIh0BNjMyFgISPVA9UEI8VFB2ZWArLOASJnsnJiswFoFDVl573mdjZ2RBSEM61wIPY14mJS6BAiAdHiIXHgqGtTdpAAAAAQA8AAACtgLQACwAfwCyBAAAK7QPBAAfBCuwFi+0FwQAHwQrAbAtL7AH1rQMBQAxBCuwDBCxIQErsBYytCIFADEEK7AiELESASuwGzK0AAUAMQQrsCgysS4BK7EhDBESsgkKDzk5ObAiEbAEObASErIeJSs5OTkAsRYPERKwADmwFxGyBwwrOTk5MDElFA4BIyImNTQ3MwYVFBYzMjY1NCYrATUzMjY1NC4DNTMUHgMVFAYHFgK2U3pKpr2DUIOAg1l+RDZZdCczKj09KlAqPT0qOCpn4UtpLcmnt6mvroivWVY2RzwqJhopHiA3JB0pGh44KCk7CykAAAAAAgA8AAACBALQAA0AGQBTALIEAAArtBcEAB8EK7ARL7QJBAAfBCsBsBovsAfWtBQFADEEK7AUELEOASuwCzK0AAUAMQQrsRsBK7EOFBESsQkEOTkAsREXERKyBgcLOTk5MDElFAcGIyImNDYzMhcRMwM0JiMiBhUUFjMyNgIEKiuOXYh6W1pJUFBZP0FPVT9CUvZTUVJwtn5BAW3+Bj9TXUI+T1gAAAAAAgBQAAACbwLkACIALQCoALIVAAArtCwEAB8EK7IcAwArsCAztAoEAB8EK7ADMrIKHAors0AKBgkrtA8mFRwNK7QPBAAfBCsBsC4vsBjWtCkFADEEK7AMMrApELEHASu0BgUAMQQrsAYQsSMBK7QSBQAxBCuxLwErsQcpERK0DxUcJiskFzmwBhGxHiw5ObAjErAgObASEbADOQCxJiwRErESDTk5sQoPERKxAB45ObAcEbAiOTAxAS4BIyIGFSM0JiMiHQE2MzIWFRQGIyImNRE0NjMyFzYzMhcDNCYjIgYVFBYyNgJvFUIjLh9QIT9YRGJpko5ne4FPUl0tKE1JNn5eSkdiYJBhAlchMEdgYEdw0T1uZmRsgnoBMlRiPDwz/h9IUE9GR1BOAAAAAgA8AAACdwLQACMALgCnALIEAAArtA8EAB8EK7AUL7QtBAAfBCuwJy+0GgQAHwQrshonCiuzQBodCSsBsC8vsAfWtAwFADEEK7MXDAcIK7QqBQAxBCuwDBCxEQErsRwkMjK0AgUAMQQrsR4iMjKxMAErsRcHERKwCTmxKgwRErAKObAREbMPBBQaJBc5ALEUDxESsgcJADk5ObAtEbESIzk5sCcStBccHyIBJBc5sBoRsCE5MDEBJxUUIyImNTQ3MwYVFBYzMj0BBiMiJjU0NjMyFzUzFTcVBxcnNSYjIgYVFBYzMgJ3cNtuggxQDFBNjk9NO1lVO0VbUHBwcMBCRCU1LyFJAS+Bwe94bSsqKSFQZK6zOUA5OkU9sbFcR0hoTxk0ISIfHgACAFAAAAIYAtAADgAZAGYAsgMAACu0GAQAHwQrsgoBACu0DBIDCg0rtAwEAB8EKwGwGi+wBta0FQUAMQQrsAgysBUQsRABK7QABQAxBCuxGwErsRAVERKyAwoMOTk5sAARsAs5ALESGBESsAA5sAwRsAk5MDElFAYjIiY1ETMRNzMHMhYGNCYjIgYVFBYzMgIYhl5ofFDPXpFeflBRP0JWVEA/0Fx0hGgB5P6drnd2nH5YUUFAWgAAAQA8AAADPALkAEkA6gCyDQAAK7QUBAAfBCuyFA0KK7NAFBAJK7IsAwArtCEEAB8EK7A2INYRtDUEADcEK7RCAw0QDSu0QgQAHwQrAbBKL7Ap1rQkBQAmBCuwJBCwESDWEbQQBQAxBCuwEC+0EQUAMQQrsCQQsRcBK7QKBQAxBCuwChCxRQErtAAFADEEK7AyINYRsEcztDkFABsEK7IyOQors0AyNQkrsUsBK7ERKRESsCc5sRckERK3DRQHHB0hJiwkFzmwChGwHjmwMhK0AwYvPUIkFzmxADkRErBIOQCxNUIREkALAAoGFx4kJykvOUgkFzkwMSUUBiMiLwEHHgEVFAYjIiYnMx4BMzI2NTQmIyIHNTcnJiMiBhUUFwcmNTQ2MzIfATc2NTQrATUzMhUUBg8BFx4CMzI2NTQnNxYDPFI6QiSEljhBbk9JYAdQBTkrLTc0LiUb8lwmOiErIT4vZUNXNWHAIDiJdJckJ8B+CAoUDhUcI0wnsjc4RPlNCFE5TVRWSCs3Pi0uPww1e6lHLiEXRSQ/PkFNX69hERcrRmwmKBRj9A8PDhkUKikgNAAAAAEAPAAAAgEC0AA3ARcAsgoAACu0FQQAHwQrsBsvtBwEAB8EK7AiL7QjBAAfBCsBsDgvsA3WtBIFADEEK7MtEg0IK7QuBQAxBCuwEhCxJgErsRgfMjK0NAUAJgQrsAUysTkBK7A2Grr6JMBFABUrCg6wKhCwKMCxMBX5sDLAuvXBwNMAFSsKsSooCLAqELAowLEwCPmwMsC6+VLAWQAVKwuwKhCzKSooEyuwMBCzMTAyEyuyMTAyIIogiiMGDhESObIpKigREjkAtSgpKjAxMi4uLi4uLgG1KCkqMDEyLi4uLi4usEAaAbEmLhEStAoVGxwiJBc5sDQRsQM2OTkAsRsVERKyDRIFOTk5sBwRsgMQDzk5ObAiErEAATk5sCMRsDY5MDEAFAYHFhUUDgIjIiY1NDczBhUUFjMyNjU0JiM1MjY1NCYjNTI2NTQuAicmNTMUHgMVFAcWAgEkIT8pRUooWYYEUARVPjlTNF1hNjZhZDA7SlgTNFA8VVU8QCABjkQyCR9UK0AiD15WLRYUKT1BNDUvFzwTLCYRPBEmHCAGCwkZUSkkBQcrLTsUDQAAAAEAHgAAAZYBwgAjAFwAsgMAACu0DgQAEwQrAbAkL7AG1rQLBQAbBCuwCxCxFwErtBwFABsEK7AcELERASu0AAUAGwQrsSUBK7ELBhESsAg5sBcRsAk5sBwSsBU5sBERsg4DITk5OQAwMSUUBiMiJjU0NzMGFRQWMzI2NTQuAzU0NzMGFRQXHgQBlm9QSHERRhFCMDJIKjs7KgRGAgYILjY0Iq1PXk9FKSEhKS40RDEqPCAeMCMUEA4GFwwQHhwmQgAAAAACAB4AAAHNAtAAFQAjAIoAsgMAACu0IgQAEwQrsAovtBEEAB8EK7QNBAASBCsBsCQvsAXWtB8FABsEK7MNHwUIK7QOBQAbBCuwHxCxCAErtBMFABsEK7QSBQAbBCuwExCxFgErtAAFABsEK7ElASuxCA4RErEDITk5sBMRsBo5sRYSERKxAiI5OQCxCiIRErMFABMaJBc5MDElFAYiJjU0Njc1IyI9ATMUFjsBBx4BBzQnJiMiBgcGFRQWMjYBzXy2fXJVcSxGCRSEC0xdRkcqJA8xDkBUfFPGWW1sWlV6ELkiUCcR8x11TVsxHRYMNFM+VlYAAgAe/ugB8gGkAC8AOQB5ALADL7Q3BAATBCuwHC+0JwQAEwQrAbA6L7AG1rQ0BQAbBCuzJDQGCCu0HwUAGwQrsDQQsRkBK7QqBQAbBCuwKhCxMAErtAAFABsEK7E7ASuxNCQRErAiObEZHxEStQ0DIScyNyQXOQCxHDcRErUGACEkKjIkFzkwMQUUBiMiJjU0PgU3PgM0NjQ2PAE1NCYjIgYVFBcjJjU0NjMyFhUUBxYXFgc0JwYVFBYzMjYB8oRjXZAdKzkyMhYDAQMBAwIBJicmKQdDClxCRjwDSRUyRpC4Z0JEW0hhb2laJUItJhYQBQEDEAQNBg0KERIXDiQ0OCcpGBwqQUteayUuORg4R201KItBTFsAAAIAHv77ApYBpAAwAD0ApACwIi+0IwQANwQrsCMQtCAEABMEK7ADL7Q7BAATBCuwCy+wNDO0KgQAEwQrsC4yAbA+L7Am1rQQBQAbBCuwEBCxBgErtDgFABsEK7A4ELExASu0AAUAGwQrsT8BK7EQJhESsSIjOTmwBhGzCyAkKiQXObA4ErEILDk5sDERsxUbAy4kFzmwABKwGjkAsSMgERKwFTmxCzsRErQGABAmLCQXOTAxJRQGIyImNTQ3LgEjIg4CFRQeBRcWFyMuAyMiBzUzJjU0PgEzMhc2MzIWBzQmIyIHBhUUFjMyNgKWbFpNZwgHMR4gLRUIJkJSX1hWHB0IUwlDXlstWVlrgiNUPEwqOllWZkY5PSYoKjY7Pj/ZWmtjTTcsHi0iOjYeQ1swHBQWMCUnNy1DIQ8SRk+hOmRHRUV0WEFZHx9gPVFSAAAAAAEAHv7oAaEBpAAiAGwAsAMvtA4EABMEK7AUL7QfBAATBCsBsCMvsAbWtAsFABsEK7McCwYIK7QXBQAbBCuwCTKwCxCxEAErtAAFABsEK7EkASuxCxwRErEIGjk5sRAXERKzAw4ZHyQXOQCxFA4RErMGCBkcJBc5MDEFFAYjIiY1NDczBhUUFjMyNRE0JiMiBhUUFyMmNTQ2MzIWFQGhZGJRbCxGLEg3gjQ+LTkTRhNkRktlS2NqYVA+PTVFN0moAS9AQTotNCEmLkZUVUoAAAABAB7+6AGhAaQAMgCUALACL7QNBAATBCuwFy+0GAQAEwQrsB8vtCoEABMEKwGwMy+wBda0CgUAGwQrsCcg1hG0IgUAGwQrsAoQsRwBK7AUMrQtBQAbBCuwADKyHC0KK7NAHBcJK7E0ASuxCicRErEHJTk5sRwiERK1Ag0IJCowJBc5ALEXDRESsgUABzk5ObAYEbAwObAfErIkJy05OTkwMQUUIyImNTQ3MwYVFBYzMj4ENTQmIzUzMjY1NCYjIgYVFBcjJjU0NjMyFhUUBgceAQGhwlJvHUYdRjkcKhoPBwI6PiAnLjguNUAIRghpUUZnNS4+KDDoY1FAOD09OUcRJiZAMCY8KDJDKS02OzUeFxoYUFVORDFKDBJdAAMAHgAAAlYC5AAZACQAMAC6ALIDAAArtC4EABMEK7IQAwArtB0EABMEK7QXKAMQDSu0FwQAEwQrtCMKAxANK7QjBAATBCsBsDEvsA3WtCAFABsEK7AgELEGASu0KwUAGwQrsCsQsRsBK7QTBQAbBCuwExCxJQErtAAFABsEK7EyASuxBiARErMKEB0jJBc5sRsrERKwCDmwExGwFTmwJRKzAxcoLiQXOQCxKC4RErEGADk5sBcRsBU5sSMKERKwCDmwHRGxDRM5OTAxJRQGIyImNTQ3BiMiJjU0NjMyFhUUBzYzMhYkNCYjIgYVFBYzMgE0JiMiBhUUFjMyNgJWZ15RcEosQT5RZUlHXjoyUUxQ/tU5Ly4xMyovASA5QEI/RD4/OdpgemlRZrgoVD5IWlVGPZQue+xePUQwKjn++ERdbEY/UV4AAAACAB4AAALAAaQAGwAnAIMAshAAACu0JQQAEwQrsB8vsAkztBUEABMEK7AZMgGwKC+wEta0IgUAGwQrsCIQsRwBK7QNBQAbBCuwDRCxBgErtAAFABsEK7EpASuxHCIRErIPEBU5OTmwDRGxCxc5ObAGErMCAwkZJBc5ALElEBESsQMCOTmwHxG0BgANEhckFzkwMSUUByM+ATU0JiMiBxYVFAYiJjU0NjMyFzYzMhYFNCYjIgYVFBYzMjYCwFNGJi06N0AoE262cnZfUT04U1Fj/q5DPUdDQ0RFPuRzXSl0ODlQNDI5XHd1XF90PT1uUz1SWElGWWcAAAEAHgAUAaMBpAAUAEYAsAgvtBIEABMEKwGwFS+wD9a0CgUAGwQrsAoQsQUBK7QABQAbBCuxFgErsQoPERKwDTmwBRGyAwwSOTk5sAASsAI5ADAxJRQHIzY1NCYiBhUUFyMmNTQ2MzIWAaM7RjtAeEE7RjttVldr13BTTnY/W1w+dFBVbld2dgABAB7+6AGfAaQAKwCAALALL7QWBAATBCuwIC+0IQQAEwQrsCcvtCgEABMEKwGwLC+wDta0EwUAGwQrsBMQsRwBK7AkMrQGBQAbBCuwADKyHAYKK7NAHCgJK7AgMrEtASuxEw4RErAQObAcEbILAxE5OTkAsSAWERKyDgYQOTk5sCERsAM5sCcSsAA5MDEBFAYHHgEVFA4CIyImNTQ3MwYVFBYzMj4DNTQmKwE1MzI1NCYjNTMyFgGfISosHAwkTDpVcyBGIEQ8HywXDQMXJygoQSZDKkJDARUyQxQUVUY5TkklY1RANTVAPEkXITs0KEw6Mm4/JDJMAAEAHv78Ay0BpAA+ANkAsCsvtCwEAB8EK7AlMrIrLAors0ArJwkrsBkvsQgQMzO0MwQAEwQrsTc8MjKyGTMKK7NAGRUJK7ALMgGwPy+wL9a0GwUAGwQrsBsQsRUBK7QUBQAbBCuwFBCxDAErtAsFABsEK7ALELEoASu0JwUAPAQrsCcQsQUBK7QABQAbBCuxQAErsRsvERKxKyw5ObAVEbIgLTM5OTmwFBKwNTmwDBGxJTc5ObALErA6ObEnKBESswgmAzwkFzmxAAURErACOQCxLCsRErAmObAZEbQAAi81OiQXOTAxARQHIzY1NCYjIh0BIzU0JiciBh0BIzU0JiMiFRQeBRcWMwQXIyYpATUzJjU0PgEzMhc2MzIWFzYzMhYDLS5GLiwoU0YnKygtRiImYRQUNxhNECoHAwFDFVIW/t//AFRxHk46TCElViM+EiVUQVQBAk1VS1grRGJoZzQtAjUpbGUpPK8xTTEmEQ4CAgEWuJQ6UaY4YklJSSkgSWAAAAACAB4AAAGjAtAAGwAnAI0AsgMAACu0JgQAEwQrsCAvtAkEABMEK7AOL7QYBAATBCsBsCgvsBXWtBAFABsEK7AQELAjINYRtAYFABsEK7AGL7QjBQAbBCuwEBCxCwErtAAFABsEK7AAELQcBQAbBCuwHC+xKQErsRwQERK1CQMOGCAmJBc5ALEgJhESsQYLOTmxDgkRErESFTk5MDElFAYjIiY1NDYzMhc1NCMiFRQXIyY1NDYzMhYVAzQnJiMiBhUUFjMyAaNcXVpybVxLNXVyAkYCaVNQXUYoJi1APkFAeNFfcnVaXHk/tIWEERMNHFJfXVD+tVghIWBDQlsAAAAAAgAeAAABowLQAB0AKgCCALIDAAArtCgEABMEK7IOAgArtBMEAB8EK7ALINYRsBAztBYEABMEK7QbIQMODSu0GwQAEwQrAbArL7AH1rQZBQAbBCuwGRCxHgErtAAFABsEK7EsASuxHhkRErULDhMDGyQkFzmwABGxEBE5OQCxISgRErEAGTk5sRYTERKwETkwMSUUBiMiJyY1ETQ2MzIWMzI3FQYjIiYjIh0BNjMyFgc0JiMiBhUUFxYzMjYBo2teRjo8VEgZYhgeHxkbHGsdWDpQWWZGPz8+PSYlLUFA0151MDF9AU9JWhMTQw4cbsM6d1tCXlZAZCMjXQAAAQAeABQCjAGkACgAXwCwFy+wCDO0IgQAEwQrsCYyAbApL7Af1rQaBQAbBCuwGhCxDgErtA0FABsEK7ANELEFASu0AAUAGwQrsSoBK7EOGhESsxccHSIkFzmwDRGwJDmwBRKyAgMmOTk5ADAxJRQHIzY1NCYjIgcGHQEjNDY1NC4DIyIGFRQXIyY1NDYzMhc2MzIWAoxJPD81NiweHjwBBAwWKBs2NT88SVxOWjMyZUpW6GFzamg5Ux0eMWMJKQsZJSkaEVM5aGp9V09tT09wAAEAHgAAAaMC0AAuAH8AsgMAACu0DgQAEwQrsBUvtBYEABMEKwGwLy+wBta0CwUAGwQrsAsQsSABK7QlBQAbBCuwJRCxEQErsBoytAAFABsEK7ArMrEwASuxCwYRErAIObElIBESsR4JOTmwERG1DgMVHSgtJBc5ALEVDhESsgYACDk5ObAWEbAtOTAxJRQGIyImNTQ3MwYVFBYzMjY1NCYrATUzMjY1NC4DNTQ3MwYVFB4DFRQHFgGjcFdPbxJHE0I2PUQvLyoqJTQvREQvBEMBL0REL1tgs1VeWU0wLDAoNUNUPjJLMjomJS4YGDMpEQ0IER4kFho+MFslKwAAAAABAAD+6AHCAaQALgCWALADL7QOBAATBCuwGC+0IwQAEwQrAbAvL7AG1rQLBQAbBCuzIAsGCCu0GwUAGwQrsBsvtCAFABsEK7ALELEmASu0FQUAGwQrsBUQsRABK7QABQAbBCuxMAErsQYbERKwHTmxCyARErEIHjk5sCYRtAkYIygpJBc5sBUSswMOEyskFzmwEBGwLTkAsRgOERKxBgg5OTAxBRQGIyImNTQ3MwYVFBYzMjURBgcWFRQGIyImNTQ3MwYVFBYzMjY1NCc1FjMyNzMBwldnU3IsRixFOYNDWDRWPTtRFkUVKCQhJiwUGWFLPD5qcF9SQDs1RTlHlAGtKQocNDs+QjkbHx8XJCkoIi8WSARAAAAAAQAeABQCjALQADEAiACwES+wCDO0KgQAEwQrsC8yAbAyL7AZ1rQUBQAbBCuwFBCxDQErtAwFABsEK7AMELEFASu0AAUAGwQrsyIABQgrtCEFABsEK7AhL7ADM7QiBQAbBCuxMwErsQ0UERK0FhcmKCokFzmwDBGwLTmwIRKyCB4vOTk5sAURsAI5ALEqERESsCg5MDElFAcjNjU0JiMiBh0BIzU0JiMiBhUUFyMmNTQ+BTUzDgQHNjMyFhc2MzIWAoxJPD81Niw8PDE3NjU/PEk2VmhnVjZJBlF1encfJzwnRBUxXk1b6GFzamg5UzkzY2EvP1M5aGp9cEt1RzYkIi4eOEoqKUs3KyskT20AAAABAB4AAAG2AtAAIAByALIDAAArtA8EABMEK7IPAwors0APCwkrAbAhL7AH1rQMBQAbBCuyBwwKK7NABwoJK7AMELEXASu0HAUAGwQrsBwQsRIBK7QABQAbBCuxIgErsRcMERKxAw85ObAcEbEVGTk5sBISsBo5sAARsB85ADAxJRQGIyInJjURNCczERQWMzI2NTQuAjU0PwEGFRQeAgG2d1h0JiUKRjxOO0ceJB4TPQseJR63VmFEQ1AByBYb/gdRVEo7JDcZIhEmHQMUEB0yIDgAAAMAHv7oAqgCWgApADQAQADEALADL7QOBAATBCuwGS+0PgQAEwQrsDgvsBQztDIEABMEK7AtL7QiBAATBCsBsEEvsAbWtAsFABsEK7ALELEbASuwHzK0OwUAEQQrsC8ysDsQsTUBK7AqMrQWBQARBCuwJTKwFhCxEQErtAAFABsEK7FCASuxGwsRErEICTk5sTU7ERK2DhgZAyInHSQXObAWEbAUOQCxGQ4RErIGCxE5OTmwPhGwADmwOBKzCQgWGyQXObAyEbEnHTk5sC0SsSUfOTkwMSUUBiMiJjU0NzMGFRQWMzI2NTQmJxYVFAYiJjU0NyY1NDYzMhYVFAceAQM0JiMiBhQWMzI2FTQmIyIGFRQWMzI2AqizlZCyS0dMjXh1hEpUJUl6S0xMSzs5TzdxhfEtJSgwLigmLiolKTItKigrQpfDvZF0e35zeaGueV13Hyg1PlhXPlEpJVc7U1I5Qi4XlgEbJjUzUj1AzyU5NykrNzoAAAABAAD+6AJRAaQAPAC4ALADL7QPBAATBCuwIy+0LgQAEwQrsB4vsBUztDQEABMEK7EoOTIyAbA9L7Am1rQrBQAbBCuwKxCxBwErtAwFABsEK7AMELEaASu0GQUAGwQrsBkQsRIBK7QABQAbBCuxPgErsSsmERKwKDmwBxGyIykuOTk5sAwSsQkxOTmwGhGyCiE0OTk5sBkSsgMPNzk5ObASEbA5OQCxIw8RErMHCRkaJBc5sC4RsCE5sB4SsyYrMTckFzkwMQUUBiMiLgE1NDczBhUUFjMyNjURNCMiBh0BIzU0JiMiDgIjIiY1NDczBhUUFjMyPgMzMhYXNjMyFhUCUXFtO21MHEAWY0VRV0skJDwPGREjHTolMT0mRiYUFBUjGRsqGh0oCCFUODkjbocrWz06LylAQ05pUwFKUjQmi4stLSs0KzswLSQsJRUkHCkpHCMdQEo5AAIAHv7oApsBpAAuADoA2gCyCAAAK7IuAAArsAMvtA4EABMEK7AeL7Q4BAATBCuwEiDWEbQTBAAfBCuwMi+wGTO0IwQAEwQrsCcyAbA7L7Ag1rQ1BQAbBCuwNRCxBgErtAsFABsEK7ALELEvASu0GwUAGwQrsBsQsRABK7AWMrQABQAbBCuwKjKyEAAKK7NAEBIJK7E8ASuxBjURErAeObALEbMIIzI4JBc5sC8SsQkdOTmwGxGwJTmwEBKzDgMnLCQXOQCxCA4RErIABhA5OTmxOBIRErAsObEyExEStRwgJSovNSQXOTAxBRQGIyImNTQ3MwYVFBYzMjU0IzUyNjU0JiMiBw4BIiY1NDYzMhc2MzIWFRQHHgElNCYjIgYVFBYzMjYCm3hmaIESQQ1WSZx6OUEvL1sGA2ugam1QZjUzYURNbTc2/rU+NjVDPz07NTxld1tkIiQhKEdDqX88QzoyRYlPYmpQT2NNTWVGdCQJWPo2QkQ1P1BRAAAAAQAe/ugBoQLKACMAdACwBC+0DwQAEwQrsBUvtB8EABMEKwGwJC+wB9a0DAUAGwQrsxwMBwgrtBcFABsEK7AMELERASuwITK0AAUAGwQrsSUBK7EcBxESsAk5sAwRsBo5sBcSsAo5sBERsgQPHzk5OQCxFQ8RErQHCRkcISQXOTAxBRQHBiMiJjU0NzMGFRQWMzI1ETQmIyIVFBcjJjU0NjMyFxEzAaEkJXhScCxGLEc4gkYkWgJACFI7TDE8PFtBQGFQPj01RThIqAEwJDV1BxAXHzpOPQGKAAAAAAEAHv78AqABpAA2AJMAsCcvtCgEAB8EK7AZMrATL7AIM7QvBAATBCuwNDIBsDcvsCzWtBYFABsEK7AWELEOASu0DQUAGwQrsA0QsQUBK7QABQAbBCuxOAErsRYsERKxJyg5ObAOEbMZJSkvJBc5sA0SsDI5sAURswMaIDQkFzmwABKxAh85OQCxKCcRErEaJTk5sBMRtAACDSwyJBc5MDElFAcjNjU0JiMiBw4BFSM0JicmIyIGFRQWFxYXFhcWFyMuAyMiBzUzLgE1NDYzMhYXNjMyFgKgNEY0NDYuJBgKPBAnFxw8NmpUgiV1IwcEVgdHal0yF3tbOUFmWihDFTpkSVvvPVFERjhPIhczYXE5Fg1lQWaEDxcMJ2IUFzFDHwwFOyyJSFt7KyRPawAAAAABAB7+6AGhAaQAJABxALADL7QOBAATBCuwFC+0HwQAEwQrAbAlL7AX1rQcBQAbBCuwBiDWEbQLBQAbBCuwHBCxEQErsCIytAAFABsEK7EmASuxCxcRErAIObAcEbAZObARErQDDgkUGiQXOQCxFA4RErEGCDk5sB8RsBI5MDEFFAYjIiY1NDczBhUUFjMyNj0BBiMiJjU0NzMGFRQWMzI2NzUzAaFhYFNvLEYsSDdEPj5CSlwzRjM5LyVDEDxIYm5gUT49NUU4SFdH4jJaSlBIRU8wRiUgxQACAAAAAAG4AuQAJAAvAJ0AsgMAACu0LgQAEwQrsh0DACuwITO0GAQAEwQrsA8ytAkoAx0NK7QJBAATBCuzFAMdCCsBsDAvsAbWtCsFABsEK7ArELEUASu0EwUAEQQrsBMQsQsBK7QABQAbBCuxMQErsSsGERKxGB05ObETFBESsB85sAsRtQkDISUoLiQXOQCxKC4RErEGCzk5sRgUERKxGh85ObAdEbAbOTAxJRQGIyImNTQ2MzIXNTQmIyIGHQEjNTQmIyIHNTYzMhc2MzIWFQI0JiMiBhUUFjMyAbhkWFxtalpRNCQiLCAxIDE/KSxDPR4nUD45RjtAPz9AQT/XWn12XVt2OvkiLTUtPDIyOj1GKT8/VED+P4ZdXkJDXQACAB4AFAGaAuQAHgAqAHsAshEDACu0IgQAEwQrsAgvtBwEABMEK7AZL7QmBAATBCsBsCsvsA3WtAwFABsEK7EZJTIysAwQsQUBK7QABQAbBCuzFAAFCCu0HwUAGwQrsB8vtBQFABsEK7EsASuxHwwRErMIAxEcJBc5sAURsAI5ALEiJhESsBQ5MDElFAcjNjU0JiMiBh0BIxE0NjMyFhUUDgIjFTYzMhYDNCYjIgYdAT4DAZpLRktBOS1TPGRRPV86X1ErOWFMWnEzHzlEJjdJKe5wam9mOk9GLOwCHlBiPzotPhwLfEdpATYeI0U5NQIIFi8AAQAe/ugCWgGkADYAewCwCS+0FgQAEwQrsB0vtB4EAB8EKwGwNy+wDNa0EwUAGwQrsBMQsSwBK7AdMrQxBQAbBCuwMRCxGQErsCIytAYFABsEK7AAMrE4ASuxLBMRErMJDxAWJBc5sRkxERKzAycoNCQXOQCxHRYRErETBjk5sB4RsQwDOTkwMSUUBgceARUUBiMiJjU0NjczDgEVFBYzMjY1NCYrATUzMjY1NCYnJicuAzU0NzMGFRQeAwJaOS4wNZVsn5pFOUZBQXh+UWs9Oz9COzwoKgMGGBghDwJGAyc3NyfLLTwJEVA0anLCo1i1SluuZYGbU088SDwjLR0gEAEDCQwXIRYYDAwNHSMTFjEAAAAAAgAeAAABowLQAAwAFwBdALIDAAArtBYEABMEK7AQL7QIBAATBCsBsBgvsAbWtBMFABsEK7ATELEKASu0AAUAGwQrsAAQtA0FABsEK7ANL7EZASuxDRMRErEDCDk5ALEQFhESsgUGCjk5OTAxJRQGIyImNDYzMhcRMwM0JiMiBhUUFjMyAaNnV1lua1lMOTxGOUI/P0BBeMBXaXW0ez8Ba/4IRFZgQ0RZAAAAAAIAHgAAAdYC5AAmADEAnQCyGQAAK7QvBAATBCuyIAMAK7AkM7QNBAATBCuwAjK0EyoZIA0rtBMEABMEK7MJGSAIKwGwMi+wHNa0EQUAGwQrsBEQsQkBK7QIBQARBCuwCBCxJwErtBYFABsEK7EzASuxCRERErUTGSAqLC8kFzmwCBGwIjmxFicRErECJDk5ALEqLxESsRYROTmxDQkRErEAIjk5sCARsCY5MDEBJiMiBhUUFxUjNTQmIyIGHQE2MzIWFRQGIyImNRE0NjMyFzYzMhcDNCYjIgYUFjMyNgHWKT8vIgExHy4iJDRRWmptXFpiOD9RIiE+Qyx5Pz9AOzk/Qj8CdT03LgUCMjUxOCwj+Tp2W112e1wBeUFTPz8p/hdCXl2GXVwAAgAe/ugCGALQACUALwCWALAFL7QQBAATBCuwFi+0LgQAEwQrsCgvtBwEABMEKwGwMC+wCNa0DQUAGwQrsxkNCAgrtCsFABsEK7ALMrANELETASuxHiYyMrQCBQAbBCuxICQyMrExASuxDRkRErAKObETKxESswUQFhwkFzkAsRYQERKyCAoAOTk5sC4RsCU5sCgStRQZHiEkASQXObAcEbAjOTAxJScRFAYjIiY1NDczBhUUFjMyNjURBiMiJjU0NjMyFxEzETcVBxcnJiMiBhUUFjI2Ahh3WW1RbCxGLEQ5SDwzWj1UVUBKPzx3d3ezRkIjLS5MSkCp/uNwdGFQPj01RTlHU0sBHUtQPT9OUAF8/n6NVG9ub1k2IyY3OAAAAgAeAAABowLQAA4AFwBRALIDAAArtBcEABMEK7ASL7QMBAATBCsBsBgvsAbWtAkFABsEK7AJELEQASu0AAUAGwQrsRkBK7EQCRESswMLDBQkFzkAsRIXERKxAAk5OTAxJRQGIyImNREzETczBzIWBjQmIyIVFBYyAaNtWlJsPJJOX11rRj5AezeCz1p1blICEP6Vo2R3oYZgmkZgAAAAAAEAAP7oApABpABNAMwAsA0vtBEEABMEK7ADL7RGBAAfBCuwHi+wODO0KgQAHwQrsDoyAbBOL7An1rQhBQARBCuwIRCxFAErtAoFABsEK7AKELFJASu0AAUAGwQrsz4ASQgrtDYFABEEK7A2L7Q+BQARBCuyNj4KK7NANjkJK7FPASuxIScRErENJTk5sBQRtwwRBxcYHiQqJBc5sTYKERK2AwYZLUFGSyQXObBJEbBMOQCxEQ0RErAOObFGAxESsgoPFDk5ObAeEUAJAAcXBiUnLT5MJBc5MDEFFAYjIi8BBx4BFRQGIic1FjMyNjU0JiM1NycuAiMiBhUUFhcHJjU0NjMyHwE3PgY1NCsBNTMyFhUUDwEXHgIzMjY1NCc3FgKQSC9AJmORKzhWhEhNMCo1LiSrUAoNHBQcKRcQMTFKOU0jVKgCCAUIBAUCNX2KJD0svF0KDB4TEh4zMzxbLjpPzXEOQipARiM9LispIytJg6oVFREkHBY2ER83NzlMSa+CAQcDBwUHBwQRPB4gNSGQxxYVFx0SJzokSAABAB4AAAG8AtAAOwEUALIDAAArtA4EABMEK7AVL7QWBAAfBCuwHC+0HQQAHwQrAbA8L7AG1rQLBQAbBCuwCxCxJgsrtCkFABsEK7ApELERASuwGTK0AAUAGwQrsDYysCEg1hG0MAUAGwQrsiEwCiuzQCEcCSuwFTKxPQErsDYauvPQwSwAFSsKDrAkELAiwLEsCPmwLsCwJBCzIyQiEyuwLBCzLSwuEyuyLSwuIIogiiMGDhESObIjJCIREjkAtSIjJCwtLi4uLi4uLgG1IiMkLC0uLi4uLi4usEAaAbELBhESsAg5sCkRsAk5sCESsg4DOTk5ObAREbAzOQCxFQ4RErIGCwA5OTmwFhGzCQg4OSQXObAcErA2ObAdEbAzOTAxJRQGIyImNTQ3MwYVFBYzMjY1NCYrATUzMjU0KwE1MzI2NC4DNTQ3MxQXHgMVFAYHHgEVFAYHHgEBvHBWZHQHRgdDTTZMICRTUkVEU1QXIDZMTDYDQRYUWUk6JxskKi8mKC2dUktmYxQaGRFOTS40Oyc8NT08Hi4YCxExKAsMJhAOFQ4vKBsrCQgxJCYvAgw8AAAAAgAA//wCWALqAD0ARQEBALIEAAArtBgEABMEK7IqAQArtCkEAB8EK7IuAQArtCEgBCoNK7QhBAAfBCuwQC+0DwQAEwQrAbBGL7AI1rALMrQWBQARBCuwRDKwFhC0CgUALwQrsAovsBYQsT4BK7QTBQARBCuwExCxHAErtAAFABEEK7AvINYRtDYFABEEK7IvNgors0AvMwkrsSApMjKwHBCwJSDWEbQ6BQARBCuxRwErsRYIERKwDDmwPhGwDzmxLxMRErIEGCM5OTmwJRGwODmwHBKwPDkAsSAYERKwADmwIRGxIzw5ObApErcJCxUIJTg6RCQXObAqEbAsObBAErMTLzY+JBc5sA8RsDI5MDElFAcGIyInJicHNTc2NzYzMhcWFRQHFRAzMjc2NTQnJic1FjMyNTQnJic1FjMyNjU0LwE1FxYVFAcWFRQHFgE0IyIHBgc2AlhVQ1+dTkMCMTIGHStWLRsYy/ZKM0AzIFA0GkU3F0U2HxYcL1htVC87OEj+pCkxHBUEj6FYKyJsW6AWNhVsU3kfHi2VVxH+xxccQDsZEQo2DTorGwsRNhIcFikdN0BFNUQ4HiM+Px0qAXozXkVLRAAAAgAe//sBbAGKABIAGwB2ALIEAAArsAAztAUEABMEK7ASMrAWL7QMBAATBCsBsBwvsAnWtBgFABEEK7IJGAors0AJBQkrsBgQsRMBK7QOBQARBCuyDhMKK7NADhIJK7EdASuxExgRErQCCwwQByQXOQCxBQQRErACObAWEbIJDho5OTkwMQUmJwYHNTY3JjU0NjIWFRQHFhcnNCYiBhUUFzYBbFdQUVYxP2lYkFhpPTNBNmA2ZmYFDCAgDDUBFzZqSFpaSGo2FQO6Mzk5M1ouLgAAAAABAB7+7gGFAXgAIQBzALAEL7QQBAATBCuwFi+0IAQAEwQrsBsvtBwEABMEKwGwIi+wB9a0DQUAEQQrsA0QsRQBK7QABQARBCuxIwErsQ0HERKxGxw5ObAUEbYKBAsZGh4gJBc5sAASsB05ALEWEBESswcAChgkFzmwIBGwGTkwMQUUBwYjIiY1NDY3FwYVFBYzMjc2NTQjIgcnNyM1IQc2MzIBhSAock5fHiQgJ0Q1ThkRWSQZIYTQASqLDgyFNHIvPVlMJzYeHykvNEExIleXGR7cNOgDAAABAB7+7gGIAscAOgDFALIIAAArsjoAACuwAy+0DgQAEwQrsBUvtBYEAB8EK7AtL7QjBAATBCsBsDsvsCDWtDAFABEEK7AGINYRtAsFABEEK7AwELERASu0AAUAEQQrsyYAEQgrtCsFABEEK7ArL7QmBQARBCuwERCwGiDWEbQ2BQARBCuyGjYKK7NAGhUJK7E8ASuxCyARErAIObAwEbAJObArErcOAx0jKCkzOCQXOQCxCA4RErIABhE5OTmxFhURErA4ObAtEbMgJig2JBc5MDEFFAYjIiY1NDcXBhUUFjMyNjU0JisBNTMyNjU0LgM1NDYzMhYVFAcnNjU0IyIGFRQeAxUUBx4BAYhoWExeKiERQTE+RlQ8LS0lWDVMTDVORjxNQB0jTCozNUxMNXNBRUZdb1hGOisaIiMxP1NESUA3PTYiMiUrSzVOaUE2SCUfFTZGSDMvPiIjQTFnKwxXAAAAAAMAHgAGAbQCygAeACgAMwCQALAFL7QyBAATBCuwKy+wADO0DAQAEwQrsB0ysA8vsBsztCgEABMEK7AZMrAiL7QVBAATBCsBsDQvsAjWsBEytC8FABEEK7AkMrAvELEpASuxDR8yMrQCBQARBCuxGBwyMrICKQors0ACGgkrsAAysTUBK7EpLxESsQUVOTkAsSsyERKwCDmxIigRErAROTAxASMVFAYjIiY1NDc2OwE1IyI1NDc2MzIWHQEzFSMVMyc1NCMiFRQXFjMTNSMiBwYVFBYzMgG0T1VGTl4yL1NcXLQwL01IU09PT4ZkciQeRk5ORR8kPTVkARp4R1VYTU8sKEiZTSgmTUVuNEh8a2FmPhYS/tt1FhpANTv//wAe/ugB8gGkEA8HCwIQAIzAAP//ADwAAgHHAkQQDwyzAgMCRsAA//8ATgDkAXMDABAPBxUAOADkMAAAAgA1AAACdwLZAAcAEAA6ALIAAAArsQgE6bIBAwArsRAE6QGwES+wANaxCAXpsAgQsQwBK7EFBemxEgErALEQCBESsQQFOTkwMTMRITIWEAYjJzMyNjU0JisBNQEZi56firysbHBwbKwC2cL+rMNSkIqLkAACADX/9gK4AtkAHwAnAMYAsg8AACuyAwAAK7EcBOmyEAMAK7EnBOm0DSADEA0rsQ0E6QGwKC+wD9axDgXpsCAysA4QsSQBK7EUBemxKQErsDYausIE8A8AFSsKDrAJELAHwLEYGPmwGsCwCRCzCAkHEyuwGBCzGRgaEyuyGRgaIIogiiMGDhESObIICQcREjkAtQcICRgZGi4uLi4uLgG1BwgJGBkaLi4uLi4usEAaAbEkDhESsBc5ALEcDxESsAE5sA0RsAA5sCASsBc5sCcRsBQ5MDElFwYjIi4GKwERIxEhMhYVFAYHHgMzMjY3ATMyNjQmKwECjykbKD1YLB4LExg1KXBdAS1sdUU8FRwPPDcGDQT+BsJDS0tDwlZHGRstOjs6LRv+ywLZb2dIZRUcYUY2BwMBNUR4RAAAAf/qAAACJgLZAAcAOgCyAgAAK7IFAwArsQQE6bAAMgGwCC+wAtaxAQXpsgECCiuzQAEHCSuyAgEKK7NAAgQJK7EJASsAMDEBESMRIzUhFQE3XfACPAKH/XkCh1JSAAAAAgAF/+kCyALZACwANADVALILAAArsREE6bIhAAArsTAE6bIwIQors0AwDgkrsiwDACu0KwQAKwQrsAEytDQlCywNK7E0BOkBsDUvsCPWsS4F6bAuELEyASuxHgXpsB4QsSkBK7EDBemyAykKK7NAAwEJK7IpAwors0ApKwkrsAMQsA8g1hGxDgXpsA4vsQ8F6bADELEUASuxCAXpsTYBK7EyLhESsyEgJyUkFzmwHhGwHDmxAw4RErAZObEUDxESsAs5ALE0MBEStAgUHiIjJBc5sCURsBw5sCsSsgQZKTk5OTAxARUjFR4DFRQGIyImNTMUMzI2NTQuAiMiBgcWFRQGIiY0NjMyFzY3NSM1AhQWMjY0JiIB6DBEa0AhWkxOTlRGJC0XL1M1P08bOVh+WFg/DQY2dTTLJjYmJjYC2UF+BD1dbDlji3NYfl1CLVVKLT48OWdab2+0bgF/GoRB/g5mPj5mPQAAAgAd/+kDrQLlAAoAJgCJALIgAAArsQUE6bIkAwArsQAE6bQLHSAkDSuxCwTptBcTICQNK7EXBOkBsCcvsCLWsQMF6bADELEIASuxHQXpsAsysB0QsQ4BK7EZBemxKAErsQgDERKyHyAkOTk5sB0RsB45sA4SsRQXOTkAsR0FERKxAyE5ObALEbAIObATErMCDhkiJBc5MDEBIgYQFjMyNjU0JhczMjU0JiMiBiM1NjMyFRQGKwEOASAmEDYzMhYBfHSOj3RzkI7lTjEbGwIQCxgXez1HTALA/sTCwp2MuQKTpf7ypaSEiqbgOhceAU8FmjFOoNPTAVbTpAAAAgA1AAAAkgLZAAMABwA2ALICAAArsgcDACu0BgQAHQQrAbAIL7AC1rAGMrEBBemwBDKxAQXpsQkBKwCxBgIRErAAOTAxExEjETcVIzWSXV1dAgb9+gIG02lpAAABACr/6QI/AuUAMgCIALItAAArsQIE6bIVAwArsRoE6bQPDi0VDSuwJTO0DwQAKwQrsCMyAbAzL7AS1rEcBemyEhwKK7NAEg4JK7AcELEIASuxKAXpsTQBK7EcEhESsAA5sAgRtwINEBUYIyYtJBc5sCgSshckJTk5OQCxDgIRErIAKDI5OTmxGg8RErISFxg5OTkwMTcWMzI+AzU0LgInITUzJjU0NjMyFwcmIyIVFB4CFxYXMxUjFhUUDgIjIi4CJ3spmC1BIhIEHDs1LP8AhG51eqI7TiVtkBwzPSUPCNZkaRQ1b1EoS0o9EZ5jDhQfFg8dMiweFUFEWWFXbylKZRcpJCESBwRBSVwmPTwiDh47KQACACT/6QL2AuUAJAAuAGkAshYAACuxBQTpsh8DACuwDjOxKgTpAbAvL7Ad1rEtBemwLRCxJwErsSMF6bAjELELASuxEwXpsTABK7EnLRESsR8AOTmxCyMRErMFDQ4WJBc5ALEqBREStAsTHSMlJBc5sB8RsA05MDE3HgMzMj4DNTQnNx4DFRQGIyIuBDUQMzIeARUUJzY1NCYjIgYVFKUVPUU6HB1DSDollSomQT4j0pIvVlNFNB28LUAb234cFzAn4zJHIQ4VMUhxRNpCShI2VH5Mr+YVLUtljlUBJ0RfNuUNMJJKU1t6TgAAAAEANQAAAbwC2QASAHUAsgwAACuyDQMAK7QCBwwNDSu0AgQAHwQrAbATL7AM1rELBemwDjKwCxCxEgErtAAFABsEK7AAELEDASu0BAUAGwQrsRQBK7EAEhESsQkQOTmwAxGwBzkAsQcMERKxCg85ObACEbAJObANErMAAwQQJBc5MDEBFDI1Fw4BIyInBxEjETMRNyYnAQtwQQZAMy8eY15ePwQEAh5paR5CSR6N/voC2f6cXQ8fAAABABj/6QJ7AtkAFwA9ALIVAAArtAoEAEIEK7IOAwArsBEzAbAYL7AA1rEHBemxGQErsQcAERKxBA45OQCxDgoRErIABBA5OTkwMTc0PgE3FwYVFBYzMj8BAzMbATMBBiMiJhgODA5HFiYOGhFM8nG5uG/+rSZVQFVkHS0SEyMsDhYbII8B5f6FAXv9X09HAAAC/+oAAAJmAtkABwAKACwAsgMAACuwBjOyBAMAK7QBCgMEDSuxAQTpAbALL7EMASsAsQQKERKwCTkwMSUhByMBMwEjCwIBs/7nTWMBBHgBAGhlcHjb2wLZ/ScBKQFM/rQAAAAAAf/r/+kBhALZABEAPwCyCQAAK7EABOmyAAkKK7NAAA0JK7IEAwArAbASL7AM1rEPBemwDxCxAwErsQYF6bETASuxAw8RErAJOQAwMTcyNjURMxEUBiMiJj0BMxUUFrdAMF1vX15tXzg3VE0CAf3dX25oWUAvQEQAAQA1AAACQALZAAsASgCyBAAAK7EBBOmyBQMAK7EIBOm0CQAEBQ0rsQkE6QGwDC+wBNaxAQXpsAgysgEECiuzQAEDCSuzQAEHCSuzQAELCSuxDQErADAxExUhFSERIRUhFSEVkgGu/fUB+f5kAY0BTPpSAtlS6VIAAwAJAAAC5gLZAAIAFwAiAJsAsgUAACuyFAMAK7QKHgUUDSu0CgQANwQrtBIHBRQNK7AAM7ESBOmwFjK0DxkFFA0rtA8EADcEKwGwIy+wDda0GwUAMQQrsBsQsQUBK7ATMrEBBemwFTKyAQUKK7NAARcJK7EkASuxBRsRErIKDyE5OTmwARGwBDkAsQoFERKwATmxBx4RErEDDDk5sBIRsRshOTmwGRKwDTkwMQEVNxcBIxEjDgEjIiY0NjMyFhczETMRISQiBhUUFjMyNjU0AanUaf7DXSkMTDQ8UlI+MkwMKV0BPf3POCMjGh0jAXv7+wH+hgF7MkFdgFxCMgEM/vQtMyIjMzIkIwAAAAEAGgAAAeQC5QAbAHMAsgIAACuyFAMAK7ENBOmyDRQKK7NADREJK7QABQIUDSuxAATpsgUACiuzQAUDCSsBsBwvsALWsQEF6bAEMrMQAQIIK7ERBemwES+xEAXpsAEQsQoBK7EXBemxHQErsQoBERKxDRQ5OQCxDQURErAXOTAxNxUjETMVMj4CNTQmIyIGFSM0NjMyFhUUDgK+Xl4mQ0AmXEMzTVR2YG+FM1hjzc0BfmAPJUo1Y2RWPmp3joZGaTkcAAAC/+P/6QKiAvAALgA5ASgAshQAACuwADOxIATpsAsysA4vtC8EADcEK7AzL7EpBOkBsDovsBfWsR4F6bAeELEDASuxCQXpsAkQsQ0BK7AwMrEsBemxOwErsDYauj+w+a0AFSsKDrAiELAlwLEQE/mwOMAFsw4QOBMruj+s+YgAFSsLsw8QOBMrsCIQsyMiJRMrsyQiJRMrBbAQELMvEDgTK7o/rPmIABUrC7M5EDgTK7IjIiUgiiCKIwYOERI5sCQ5sg8QOBESObA5OQC3DxAiIyQlODkuLi4uLi4uLgFACg4vDxAiIyQlODkuLi4uLi4uLi4usEAaAbEeFxESsBk5sAMRsRQaOTmwCRKwBDmwDRGzAAUpMyQXOQCxIBQRErACObAOEbMDBBcZJBc5sTMvERKwLDkwMQUiJjQ3MxQOARUUMzI3IQ4EIyImNTQ3MxQOARUUMzI+BjMyFhUUBgEhNCYjIg4EAdI7TBBPBAMsZg7+3QUMGiU9KTxLEE8EAywiKg8MCB0uXkJ3anD+8wEgQFMbKx0TDQYXOkYqAQ8RCCrmOFBaNyQzKiMqAQ8RCCo7YXyAfGE7wrrOvQGDmJoWLjFQPQAAAAABADUAAAHuAtkABwA2ALIGAAArsgcDACu0AQQGBw0rsQEE6QGwCC+wBtaxBQXpsAAysgUGCiuzQAUDCSuxCQErADAxExEhFSERIxGSAVz+pF0C2f7FUv60AtkAAAEANQAAAhkC2QAFACwAsgMAACuyBAMAK7EBBOkBsAYvsAPWsQIF6bICAwors0ACAAkrsQcBKwAwMQEhESMRIQIZ/nxgAeQChf17AtkAAAAAAv/9/+kDDQLlADIAQQDFALIAAAArsC8zsRcE6bAkMrIeAwArsTsE6bQoKQAeDSu0KAQAKwQrsCsyAbBCL7AD1rEUBemwFBCxGwErsUAF6bBAELE1ASuxIAXpsCAQsScBK7EsBemyLCcKK7NALCsJK7InLAors0AnKAkrsUMBK7EUAxESsAg5sBsRsAk5sEASsRcAOTmwNRG0HR4iMRkkFzmwIBKxJC85OQCxFwARErAxObAoEbQPAxkiMyQXObApErEOCTk5sDsRtBsgCDVAJBc5MDEXIiY1ND4CNxcOCRUUFjMyNyY1NDYyFhUUBxYzMjY3IzUzFSMOASMiJwY3NjU0LgMiDgMVFMtibBIkExE8AQsDCwQJBQYDAj8wKy93Z6pndy8qMkAHNsIvCWVoUkxNTV8PFhsWEhYbFg8XYkkgNikSDUgBCAIJBQoICwsNBywuGYG7q6qqq71/GUtJQUFihDExn2OlPF83JA0NJDdfPKUAAQACAAADjQLZAAwAdQCyBAAAK7EBAzMzsgUDACuyCAkLMzMzAbANL7EOASuwNhq6PcHvMgAVKwqwCC4OsAfAsQIE+QWwA8C6wmHuuAAVKwqwAS6xAwIIsALADrEKCvkFsAnAAwCyAgcKLi4uAbYBAgMHCAkKLi4uLi4uLrBAGgAwMSEjCwEjAzMbATMbATMC1Gaoo2a7aImiZKaGaAJX/akC2f2wAlD9sAJQAAIADf/pAjcC5QAQADIAewCyKwAAK7EIBOmyGQMAK7EgBOmzHSsZCCsBsDMvsDHWsQIF6bACELETASuxIgXpsCIQsQsBK7EoBemzHSgLCCu0HAUAPAQrsTQBK7EiExESswAIESskFzmwCxGyGSAlOTk5ALEdCBEStAARJSgxJBc5sCARsRMiOTkwMQEGFRQeAzMyNjU0LgMnJjU0PgMzMhYVIzQmIyIVFB4DFRQGIyIuAzU0ASbBGSUxKBRCSgwfEjI6FgUWIkIrVVtTLCVZKDg4KHBxIEFMOSYBmSWSKj8iFQZMSRgrLhk2USo0DCEyKB5dbDVCUiFEPUNaMmCHCyE1XTy9AAAAAAEAMgAAAgcC8AAXAEwAsgEAACuwDS+xDgTpsBQvsQUE6QGwGC+wAdaxAAXpsAAQsREBK7EKBemyEQoKK7NAEQ0JK7EZASuxEQARErAFOQCxFA4RErAKOTAxMyMRNDYzMh4CFRQGIzUyNjU0JiMiBhWPXYljKU1IK3BcNThTOENLAiNccRUuVzxadE5EQD1HWkcAAAABAB7/6QKHAuUAKgCSALIAAAArsRgE6bIMAwArsRIE6bISDAors0ASDwkrtCMeAAwNK7EjBOmyHiMKK7NAHiAJK7IjHgors0AjIQkrAbArL7AG1rEVBemwFRCxIAErtB8FABsEK7AiMrAfELEbASuwDzKxJgXpsA4ysSwBK7EfIBESswwSABgkFzkAsR4YERKwJjmwIxGyBhUkOTk5MDEFIi4DNTQ+AzMyFyMuASMiBhUUFjMyNjU0JicVIzUzFR4BFRQOAgFnS3dHLxERMEd5TO4rXxBeV2p7gG1eYUhTRkZ+fR9BdBczTmlgMTJiak807k5OooyJoU86QT0FUexJB29fKEtBJwABADUAAALjAtkADABGALIEAAArsQAKMzOyBQMAK7AIMwGwDS+wBNaxAwXpsAMQsQsBK7EKBemxDgErsQsDERKxBgg5OQCxBQQRErICBww5OTkwMSEjAxEjETMbATMRIxEBvmLPWIHY1IFYAmP9nQLZ/YUCe/0nAmMAAAAAAQAcAAAB8QLwAB4AYACyCgAAK7AML7EXBOmwEC+xEQTpsBwvsQUE6bIcBQors0AcAAkrAbAfL7AA1rEeBemwHhCxCgErsBgysQkF6bEgASuxHgARErEQETk5sAoRsQUVOTkAsREQERKwFTkwMRM0PgIzMhYVESM1IyImKwE1MzIeAjsBETQmIgYVHCtITCpjiV2BG1MbVX0SJRslEllLhkgCHjtXLBRxXP3dlmBSHiQeARlHWkRAAAL//v/pA1MC2QAOAEIAtQCyIwAAK7QJBAA3BCuyNAMAK7QzBAArBCuwNjK0OhcjNA0rsToE6bQ/EiM0DSuxPwTpshI/CiuzQBJCCSsBsEMvsCbWsQQF6bAEELEMASu0HgUAPAQrsB4QsQ8BK7RCBQAxBCuxRAErsQwEERK2GyMpLjIzNCQXObAeEbEZNzk5sA8StBc1Njo/JBc5ALEXCREStgAbHiYpKywkFzmwOhGyFS4wOTk5sBISsBk5sD8RsD05MDEBDgIVFB4CMzI2NTQmJTQmIyIOAiMiJwYHHgEVFA4CIyImNTQ2NwYHJzYzMhc2NyM1MxUjHgEzMj4CMzIWFQEiHSAbFB4ZDDQzOQGzKysQIhw2IFgnFB4+Rh45PilQVy0qYjY3SrIMBkMNM8I2CCghEiMaNCFNXAFrJzJQKSAtEwhDWiJklB4qJSwlUiwuI5E2RFwtEmhCSGY3BlA+agFfcEFBPVImLyZaQgAAAgAe/+kDiQLlABIAHQB8ALILAAArshAAACuxGQTpsggDACuyAwMAK7ETBOm0Bg0QAw0rsQYE6QGwHi+wANaxFgXpsBYQsRwBK7ENBemwBjKwDRCxCwErsAcysQoF6bEfASuxHBYRErEQAzk5sA0RsA45ALENGRESsBs5sAYRsQAWOTmwExKwHDkwMRM0NjMyFhczETMRIxEjDgEjIiYBIgYVFBYzMjYQJh6vno2rEHheXnYIsZWOuwFNdHx+cXJ9fQFhs9GwlwE7/ScBTKLB2gHQo42HoaIBFKIAAAEANQAAAmYC2QALAD8AsgMAACuwCjOyBAMAK7AIM7QGAQMEDSuxBgTpAbAML7AD1rECBemwBTKwAhCxCwErsAcysQoF6bENASsAMDEBIREjETMRIREzESMCCf6JXV0Bd11dAUz+tALZ/sUBO/0nAAABABj/6QHWAtkAHQCEALIJAAArsQ8E6bIPCQors0APDAkrsh0DACu0HAQAKwQrsAEyAbAeL7AM1rENBemwDRCxGgErsQMF6bIDGgors0ADAQkrshoDCiuzQBocCSuwAxCxEgErsQYF6bEfASuxDQwRErELGDk5sBoRsBc5sAMSsgkPFTk5OQCxHA8RErAGOTAxARUjFR4BFRQGIyImJzMWMzI2NTQmIyIHJzY3NSM1AUUwWWh9a15wCFQVa0VOTURNH0gnVjQC2UGADph1f5VrYH5qXWJvPCxHEYJBAAAAAAEADP/pAqcC2QAXAGEAshIAACu0BwQAQgQrsgsDACuwDjO0FwASCw0rsRcE6bACMgGwGC+wFdaxBAXpsgQVCiuzQAQCCSuyFQQKK7NAFRcJK7EZASuxBBURErALOQCxABcRErAKObALEbANOTAxEzMVIxUUFjMyPwEDMxsBMwEGIyImPQEjDNRDJg4aEUzycbm4b/6tKFNAVTgBAlQ4FhsgjwHl/oUBe/1fT0c0SgAAAwAd/+kC3QLlAAoAEQAXAGUAsgMAACuxFgTpsggDACuxDgTptBMRAwgNK7QTBAA3BCsBsBgvsAbWsRMF6bARMrATELESASuwCzKxAAXpsRkBK7ESExESswgMEAMkFzkAsRMWERKwBTmwERGwADmwDhKwBjkwMQEUBiMiJhA2MzIWBy4BIyIGBwUhHgEyNgLdwKCewsKdoMFeCItwbY0HAgP9/gyL1IwBYaLW0wFW09SQfZWWfEZ1i4wAAAABABf/fgHmAtkAGQB9ALIEAAArsRcE6bIXBAors0AXGAkrsgwDACuyCgEAK7AOM7QJBAA3BCuwEDKwAS+0AgQANwQrAbAaL7AH1rALMrESBemwDTKyEgcKK7NAEhAJK7IHEgors0AHCQkrsBIQsQMBK7AXMrEABemyAwAKK7NAAwEJK7EbASsAMDEFITUzNS4BPQEjNTM1MxUzFSMVFB4CMzUzAeb+4cKhkUBAXby8FDhIQV2CRjwCW3P2Rs3NRugwOR4JnQAAAAEAHv/pArcC5QAkAJsAsg8AACuyEgAAK7EGBOmyGwMAK7EiBOmyIhsKK7NAIh8JK7QLDBIbDSuxCwTpAbAlL7AV1rEABemwABCxCQErtA0FADwEK7IJDQors0AJCwkrsA0QsB4g1hGxHwXpsB8vsR4F6bANELQPBQARBCuwDy+xJgErsR8AERKyBhIbOTk5sAkRsBA5ALELBhESsBA5sAwRsQAVOTkwMRMUHgMzMjY9ASM1IREjJwYjIiY1ND4DMzIWFyMuASMiBnsOJDlePGSB3gEwOxdokZS6EjJLf1B9oRNfD3FTdIwBaiZNVD8pfmIUUv57YXTUqDBhalA1em9GUaMAAf/m/+kDCALmADEAhwCyJAAAK7IEAAArsQ8E6bAtL7EXBOkBsDIvsAnWsQ0F6bEzASuwNhq6Puz0TQAVKwoOsBIQsBPAsQEJ+bAwwLMAATATK7IAATAgiiCKIwYOERI5ALQAARITMC4uLi4uAbQAARITMC4uLi4usEAaAbENCRESsAs5ALEtDxESswkLISgkFzkwMQEDDgEjIi4CNTQ3FwcUMzI2NxM2NzY3Mh4IFxMjAy4GIyIGBwYBNTYKSCwvQh4MEE4IPhEaBD4WDy1iEyAaGBEUDBIKFAahW44MGg4TDhMWDiIeFgUBiv7NOzMYKScWHycOKjkZFgFngSloAgcKFhIkGTAePRH+LAGKIE0rMhoXCVl/HQAAAAABADUAAAIfAtkADgA5ALINAAArsAYzsg4DACu0AQsNDg0rsQEE6QGwDy+wDdaxDAXpsAAysAwQsQcBK7EGBemxEAErADAxExEzMhYdASM1NCsBESMRkqBmh12ph10C2f7thFbs0qL+jALZAAABABAAAAI7AtkACQAsALIFAAArsQIE6bIJAwArsQgE6QGwCi+xCwErALECBRESsAY5sAgRsAE5MDEBFQEhFSE1ASE1Ajn+TAG2/dUBtv5mAtlU/c1SUgI1UgAAAAEAHAAAAiAC8AAhAGwAsg0AACuwDy+xGgTpsBQvsBcztBUEACsEK7ACL7QDBAArBCuwADKwHy+xCATpAbAiL7AU1rACMrQXBQALBCuwADKwFxCxDQErsBsysQwF6bEjASuxFxQRErMEExghJBc5sA0RsQgfOTkAMDETFSM1Mz4CMzIWFREjNSMiLgEnIzUzFSMWOwERNCYjIgfewjIJT1o0Y4ldjzNZTgszwi4YbY5LQ3AWAkdBQT5QG3Fc/d2yGkw8QUFUAQFHWlsAAAIAHf/pA/MC5QAKACMAnQCyGAAAK7EFBOmyHQMAK7EABOm0DRIYHQ0rtA0EAB8EKwGwJC+wG9axAwXpsAMQsQgBK7EVBemwFRCxIwErtAsFABsEK7ALELEOASu0DwUAGwQrsSUBK7EIAxESsRgdOTmwFRGwIDmxCyMRErEUITk5sA4RsBI5ALESBRESswMIFRokFzmwDRGyAhQgOTk5sAAStAsODxshJBc5MDEBIgYQFjMyNjU0JgUUMjUXDgEjIicHDgEjIiYQNjMyFhc3JicBfHSOj3RzkI4BUHBBBkAzLx5QAcCfnsLCnYi2GjUEBAKTpf7ypaSEiqY3aWkeQkkecqHV0wFW05uGTA8fAAAAAQAYAAACVALZAAsARwCyAQAAK7ECBOmwCjKyBgMAK7EFBOmwCDIBsAwvsAPWsQoF6bIKAwors0AKAAkrsAcysgMKCiuzQAMBCSuwBTKxDQErADAxKQE1MxEjNSEVIxEzAlT9xO/vAjzv71ICNVJS/csAAAABAAr/6QMVAvAAOgCOALIkAAArsCAzsTQE6bAHMrAML7EVBOmyDBUKK7NADBAJKwGwOy+wJ9axMQXpsDEQsTgBK7EEBemwECDWEbEPBemwBBCxCQErsRsF6bE8ASuxEDERErMkLC00JBc5sQ84ERKwNjmwBBGxACI5ObAJErMBDBUgJBc5ALE0JBESsCI5sAwRswAbJywkFzkwMQEXDgEVFBYzMhE0JiMiBhUjND4CMzIeAxUUDgIjIicGIyImNTQ+AjcXDgIVFBYzMjcmNTQ2AXpEEhxVS4iLTEo0XydDSSlDbEUuExMvYERiREFVcXgXKx4XJBIWFEJJMykfLQGKPRVFG0RdAR+Jwz9FPFYsFDdZd3c+P2pnOzQ0ensnQzIaEUkPGTgkR1omNksnaAAAAgAQ/+kCwALlACoAOQCxALIhAAArsTME6bIDAwArsAczsScE6bAaMrInAwors0AnAAkrtBQNIQMNK7QUBAApBCsBsDovsADWsSoF6bAqELEjASuxLQXpsC0QsTgBK7EeBemwHhCxFwErsQoF6bE7ASuxLSMRErIhAyc5OTmwOBGxBSU5ObAeErEcIDk5sBcRswcNEBokFzkAsQ0zERKzHiMtOCQXObAUEbAQObAnErQKERwlKyQXObADEbAFOTAxEzQ2MzIXNjMyFhUUBiMiJic3HgEzMjY1NCYjIgcWFRQGIiY1NDcmIyIGFTcGFRQeAzI+AzU0EGBIQzxGUX50PjwiNxw+FA8MExBCUS8uV0iiSGIhHx00zEAIDBAQEBAQDAgB1ImIMTFtWFpkLjE4IxElNTFDH325s6Kis8F6GmBfYF+XPV44Iw0NIzhePZYAAf/4AAAEcgLlADEAjQCyAQAAK7IOAwArsBEzshgDACuxKwTptAsEARgNK7ELBOm0FC8BGA0rsRQE6QGwMi+wB9a0CAUAGwQrsAgQsSkBK7QaBQAxBCuxMwErsSkIERKzBBggISQXOQCxBAERErAQObALEbAgObAvErEhJDk5sBQRtgcCGiUpLTEkFzmwKxKwCDmwDhGwFjkwMSEjAwYjIiYnNx4BMzI2NTMbATMUMzI+ATMyFRQOAwcnNz4FNTQjIg4BIyInAj5kwSNbQ1oGQQU1KCMqZMK2YzALMz8ahBMVLBEWGQoJBhIICwUxDDI/GjogAkVrTkIjMThoTf2bAmVZMjNoITMdGgcIRQMDBAkLEBcOIDMyJgAAAAABAAr/6QMVAvAAPwCnALImAAArsCIzsTYE6bAJMrAEL7Q9BABCBCuwDi+xFwTpsg4XCiuzQA4SCSsBsEAvsCnWsTMF6bAzELE6ASuxBgXpsBIg1hGxEQXpsAYQsQsBK7EdBemxQQErsRIzERKzJi4vNiQXObEROhESsDg5sAYRsCQ5sAsStAAOFyI9JBc5ALE2JhESsCQ5sAQRtQABHSkzOiQXObA9ErELLzk5sA4RsC45MDEBBy4BIyIVFBYzMhE0JiMiBhUjND4CMzIeAxUUDgIjIicGIyImNTQ+AjcXDgIVFBYzMjcmNTQ2MzIWAkdODiMOKmU7iItMSjRfJ0NJKUNsRS4TEy9gRGBIQFRxeBcrHhckEhYUQkkxJxtIOChQATMtGyKHPEkBH4nDP0U8ViwUN1l3dz4/amc7MjJ6eydDMhoRSQ8ZOCRHWiIsPW5vOQAAAQAk/+kCPgLlADYAmgCyJgAAK7ESBOmyNAMAK7ECBOm0Fx0mNA0rsRcE6bAXELAaINYRsRsE6bQHCiY0DSuxBwTpAbA3L7As1rENBemwMiDWEbEEBemwDRCxFQErsSAF6bE4ASuxFQQREkAJAAgJEhodJi80JBc5sCARsDY5ALEaEhESsRUgOTmxGxcRErENLDk5sQcKERKwLzmwAhGyADI2OTk5MDEBJiMiFRQWOwEVIyIGFRQeAjMyNjU0IyIGIzU2MzIWFRQOAyMiLgM1NDY3LgE1NDMyFwHKH3iZXUE4TEJhDyRPOF1JRBc6AjIpPlsaKkRFMEFnPigPRT04Mfm5LwJHUGcsSVJmMBcuMyAgLCsIUQpAMys9JRUHIjNEPR0/bBcYODXChAAAAgAy/+kCYgLZAAwAFQBJALIFAAArsRIE6bIJAwArsAAzsgsBACu0DgQANwQrAbAWL7AI1rEPBemwCjKwDxCxFQErsAAysQIF6bEXASuxFQ8RErAFOQAwMQEzERQGIyImNREzFSEVIRUUFjMyNjUCBV2ZgIKVXQF2/oplVVhkAtn+AG6CgW8CAM1G7U9PVEoAAgAG/+kDbALwACoAMgCmALIJAAArsSEE6bIQAAArsS4E6bAyL7EUBOmyFDIKK7NAFBoJK7AnL7EDBOkBsDMvsBLWsSwF6bAsELEwASuxDQXpsA0QsRgBK7EbBemwGxCxJAErsQYF6bE0ASuxMCwRErIQDxQ5OTmwDRGyABcqOTk5sRsYERKwDDmwJBGyAwknOTk5ALEyLhEStQ0REhcYDCQXObAUEbEGJDk5sCcSsQAqOTkwMRM+ATMyFhUUBiMiJicHDgEiJjQ2MzIWFzc1MxUUHgMzMjY1NCYjIgYHAhQWMjY0JiLoMqRLs7CajGV3CysBV35YWD8yTg8xXwMPGzcnWW+Kezt9I9MmNiYmNgJsQETwzJO4c2oUWm1vtG5HPheGdCIwSC0ikI+QvDI2/q1mPj5mPQAAAgAGAAACPQLZAAoADQBcALIIAAArsgEDACu0Cg0IAQ0rsAMzsQoE6bAFMgGwDi+wCNawCzKxBwXpsAIysgcICiuzQAcFCSuyCAcKK7NACAoJK7EPASuxBwgRErABOQCxAQ0RErEADDk5MDETATMRMxUjESMRISU1BwYBPV2dnV3+wwE91AFfAXr+hVL+9AEMUvv7AAIANQAAAlUC2QALABQAOgCyBAAAK7EMBOmyBQMAK7QHFAQFDSuxBwTpAbAVL7AE1rEMBemwBjKwDBCxEAErsQAF6bEWASsAMDElFAYjIREzETMyFhUFMzI2NTQmKwECVYJk/sZdpZaI/j3UQFJRQdTiY38C2f7qeGaTUj1AUAAAAQAGAAAB1QLZABkAkQCyFwAAK7IJAwArtAAGFwkNK7EABOmyBgAKK7NABgMJK7QNExcJDSuxDQTpshMNCiuzQBMRCSsBsBovsAPWtAQFABsEK7AEELEXASuwCDKxFgXpsAoysBYQsREBK7QQBQAbBCuxGwErsRcEERKwADmxERYRErANOQCxBgARErAYObATEbEIFTk5sA0SsAs5MDETIiY1MxQzMjcRMxE2MzIWFSM0IyIHESMRBoFBOkkwFCxeJxZBOkkwFSpeJwEFTExOHAFu/s4WTExOG/6oARsWAAADABj/6AKbAuIACgA9AEcAywCyFQAAK7EFBOmyIwMAK7FDBOm0NDMVIw0rsTQE6bQtOhUjDSuxLQTpAbBIL7AX1rQCBQAxBCuwAhCxIAsrtEYFADEEK7APMrBGELEIASuwQDK0EgUAMQQrsCYysBIQsTcBK7QwBQAxBCuyNzAKK7NANzMJK7FJASuxRgIRErEAFTk5sAgRtgUOHB0jPkMkFzmwEhKxCxQ5ObA3EbEtPDk5ALEzBRESswAOEhckFzmxOjQRErQcCx0wPiQXObAtEbQmIClARiQXOTAxEwYVFBYzMjY1NCY3DgIHHgEVFAYiJjU0PgM3LgE1NDYzMhYVFAYVPgIzMhYVFAYjNTI2NTQmIyIOASc2NTQmIyIGFRR8FDEzKCRVehAuPA5TYE2aaRcuKkAQNzhHOUJAARkgNhpNXFhFICwrKxE6S1IOHBQYGgEGKDAyQDMnIzzEFiYqCx5eNkhmdFIwTDYiLQ4QUjM7VVY+BBADGBobWkI7U1EiGx4qMTxAISofISUXSgAAAQA1AAACRgLZABgAbACyDgAAK7AAM7IPAwArsQwE6bQEAw4PDSu0BAQANQQrAbAZL7AO1rENBemwDRCxCAErsAAysRMF6bAYMrIIEwors0AIAwkrsRoBK7EIDRESsBY5ALEDDhESsBY5sAQRsAY5sAwSsQgTOTkwMSE0Jic1FhcyNTQmKwERIxEhMhYVFAYHFhUB5a1mPziZS0PCXQEtbHVPQ5V3xSBfFR+APET9eQLZb2dNaRGHtQAAAAABADP/6QHMAtkAEQA/ALIJAAArsQAE6bIACQors0AABQkrsg0DACsBsBIvsAzWsQ8F6bAPELEDASuxBgXpsRMBK7EDDxESsAk5ADAxJTI2PQEzFRQGIyImNREzERQWAQA1OF9tXl9vXTA3REAvQFlobl8CI/3/TVQAAAAAAf/zAAADggLZABEALQCyAQAAK7APM7ICAwArsgYJDTMzMwGwEi+xEwErALECARESswQIDBEkFzkwMSEjATMbAQMzFzczAxsBMwMjAwFdZP76ZNZhc2Q+OmNuacpj/WRkAtn9lwEpAUCysv7E/tMCaf0nARUAAAAAAQAg/+kCNALlADUAlACyMAAAK7ECBOmyEwMAK7EdBOm0JykwEw0rtCcEACsEK7QaGTATDSu0GgQAKwQrsBYyAbA2L7AQ1rEfBemwHxCxCAErsSgF6bArMrE3ASuxHxARErAAObAIEbcCDBMZGyYpMCQXObAoErIWFxg5OTkAsSkCERKzAAgrNSQXObAnEbAMObAZErAkObAaEbEQHzk5MDE3FjMyPgM1NC4FNTQ2MzIWFzMVITUzJiMiFRQeAhcWFzMVIxYVFA4CIyIuAidwKZgtQSISBC5KWVlKLnV6UHETN/8AbSRXkBwzPSUPCNZkaRQ1b1EoS0o9EZ5jDhQfFg8kPS0sLTNIKmFXWEZBQVBlFykkIRIHBEFJXCY9PCIOHjspAAEAAv/pAowC2QAaAG8AsgkAACuxFgTpshEDACuxDgTpsg4RCiuzQA4QCSu0AQAJEQ0rsQEE6QGwGy+wENa0DwUAJgQrsA8QsQwBK7ETBemwExCxGQErsQQF6bIZBAors0AZAQkrsRwBK7EZExESsAk5ALEAFhESsAQ5MDEBNTIWFRQOAiMiJjURIxUjNSERFBYzMjY0JgHAXHAiPEQpX2+lTAFOMEA1ODgBP050WjxXLhVuXwHPZ7v9/01URIBEAAH/5gAAAcwC2QAKAD4AsgUAACuwATOyCgMAKwGwCy+wBtaxCAXpsAgQsQIBK7AJMrEBBemxDAErsQgGERKwBDkAsQoFERKwAzkwMQERIxEBIzUzFQE1Acxg/tpgYAEmAtn9JwFJ/re5JQFK+wAAAAABAAkAAAHvAtkADABNALIHAAArsAMzsgEDACuxAATpAbANL7AI1rEKBemwChCxBAErsAsysQMF6bIEAwors0AEAAkrsQ4BK7EKCBESsAY5ALEABxESsAU5MDETNSERIxEBIzUzFQE1bQGCYP7aYGABJgKFVP0nAUn+t7klAUqnAAH/8wAAAloC2QAGACEAsgEAACuyAgMAK7AFMwGwBy+xCAErALECARESsAQ5MDEhIwEzGwEzAV1k/vpk1spjAtn9lwJpAAAAAAEAIP/pAjQC5QArAFoAsiYAACuxAgTpshMDACuxGATpAbAsL7AQ1rEaBemwGhCxCAErsSEF6bEtASuxGhARErAAObAIEbUCDBMWHSYkFzmwIRKwFTkAsRgCERK1ABAVFiErJBc5MDE3FjMyPgM1NC4FNTQ2MzIXByYjIhUUHgQVFA4CIyIuAidwKZgtQSISBC5KWVlKLnV6ojtOJW2QPl1tXT4UNW9RKEtKPRGeYw4UHxYPJD0tLC0zSCphV28pSmUgPS06OVgzJj08Ig4eOykAAAAAAgAj/+kDQwLkACwANwCWALIYAAArtDIEADcEK7IhAwArsCYzsQ8E6bAGMrQALBghDSuxAATpAbA4L7Ac1rEvBemwLxCxNQErsRUF6bMKFTUIK7EJBemwFRCxAwErsSkF6bE5ASuxNS8RErMPGCERJBc5sQkVERKxDCQ5ObADEbIAJiw5OTkAsSwyERKzHBUvNSQXObEPABEStQkRJCk3LSQXOTAxAT4BNTQmIyIGByc2NTQmIyIHHgIVFAYjIi4BNTQ+AjMyFhc2MzIWFRQGByUGFRQWMzI2NTQmAo8uLzQqL18IVwtLLFgwVXYycFk7WCsdPm5JQGQYRVhXXlZN/e4TPC4rRWABsAlBKS1DjkQaKhs/NFQJYIFMc61imlpQkHxJMjFjbExIdg6PS2dsoIpUWX8AAAAABP/7/+gCvALmAAcAMwA8AEUAqQCyDQAAK7AtM7E4BOmwQjKwAC+xHQTpAbBGL7AQ1rE2BemwNhCxOwErsQoF6bAaINYRsQIF6bAKELEwASuxPwXpsAYg1hGxIAXpsD8QsUQBK7EqBemxRwErsRo2ERKyDTQ4OTk5sQI7ERKxCBg5ObEwChESswQAHTMkFzmxPwYRErEiMjk5sUQgERKyLT1COTk5ALEAOBESQAoEChAaICowMzQ9JBc5MDEBIhUUFzY1NAMWFRQGIyImNTQ+BTcmNTQ2MzIWFRQHHgYVFAYjIiY1NDcnBwYVFDMyNjU0JQYVFBYzMjU0AVsyMzKcRFJKRlkSKCRCJ00OUVE+P1FRDk0nQiQoEllGSlJEabFTPBwpATMuKRw8ApQ+JjAvJz7+tlJGYWlGSh88OCs3HjcKSj5ETk5EPkoKNx43Kzg8H0pGaWFGUk+LTkg+PDYsNjYsNjw+SAAAAQAyAAAB9wLlABMATgCyBwAAK7EEBOmyCwMAK7EABOmyAAsKK7NAAA8JKwGwFC+wB9axBAXpsgQHCiuzQAQGCSuwBBCxEAErsQ8F6bEVASuxEAQRErALOQAwMQEiBhURIRUhETQ2MzIWHQEjNTQmAP9AMAFo/jtvX15tXzgCl1RN/lxSAhhfbmhZQC9ARAAAAQA1AAAB+gLZAAUALACyBAAAK7EBBOmyBQMAKwGwBi+wBNaxAQXpsgEECiuzQAEDCSuxBwErADAxExEhFSERkgFo/jsC2f15UgLZAAEAHv/pApMC5QAdAGMAshgAACuxEgTpshIYCiuzQBIVCSuyBgMAK7EMBOmyDAYKK7NADAkJKwGwHi+wANaxDwXpsA8QsRUBK7EWBemwCSDWEbEIBemxHwErsQkPERKyBhIYOTk5ALEMEhESsAA5MDETND4DMzIXIy4BIyIGFRQWMzI2NzMCISIuAx4RMEd5TO4rXxBeV2p7gG1aYBFgIf71S3dHLxEBZDJiak807k5OooyJoWVq/t8zTmlgAAAAAAMAEf/pAqsC2QAWAB4AJgCLALIGAAArsSME6bIUAwArtCASBhQNK7EAFzMzsSAE6bEBCTIytA4aBhQNK7EOBOkBsCcvsAvWtB0FADwEK7AdELEIASuwFzKxIQXpsBEysCEQsSYBK7ATMrEDBemwFTKyAyYKK7NAAwAJK7EoASuxCB0RErAOObEmIRESsQUGOTkAsRoSERKwCzkwMQEVIxUUBiImPQEmNTQ2MzIWHQEzETMRJTU0IyIGFRQFIxUUMzI2NQKraWaeYstQQz1QtF3+mjkdIgGBtF0sKwGCTn5dcGlYigaQTWJXO2UBV/6pAU5aNSw/V3mEWEkAAAIACP/pAxgC5QAoADcAyACyFAAAK7ExBOmyJQMAK7AAM7EaBOmwDTK0BwYUJQ0rtAcEAEIEK7QhIBQlDSu0IQQAKwQrsB0yAbA4L7Ai1rEdBemyHSIKK7NAHR8JK7IiHQors0AiIAkrsB0QsRYBK7ErBemwKxCxNgErsREF6bARELEKASuxAwXpsTkBK7ErFhESsRolOTmwNhG0ExQYJw8kFzmwERKxDQA5ObAKEbEGBzk5ALEGMRESsxEWKzYkFzmxGiERErQKAw8YKSQXObAlEbAnOTAxATIWFRQGIycyNjU0JiMiBxYVFAYiJjU0NyYjIgYHMxUjNTM+ATMyFzYHBhUUHgMyPgM1NAJKYmxcQBAmJz0yKy93Z6pndy8qMkAHNsIvCWVoUkxNTV8PFhsWEhYbFg8C5WpTVWdcNyg4NBmBu6uqqqu9fxlLSUFBYoQxMZ9jpTxfNyQNDSQ3XzylAAAAAgA1AAACQwLZAAoAEgBCALIGAAArsgcDACuxEgTptAQLBgcNK7EEBOkBsBMvsAbWsQUF6bALMrAFELEPASuxAAXpsRQBKwCxEgsRErAAOTAxARQGKwERIxEhMhYFMzI2NCYrAQJDcVvlXQEtbHX+T8JDS0tDwgIDXXH+ywLZb+NEeEQAAQAf/+kCiwLlACcAeACyIgAAK7EXBOmyBgMAK7ERBOmyDQEAK7AJM7EMBOkBsCgvsADWsRQF6bAUELEaASuwDjKxHwXpsAkysh8aCiuzQB8LCSuyGh8KK7NAGgwJK7EpASuxGhQRErMGERwiJBc5sB8RsB05ALEMFxESswAUHR8kFzkwMRM0PgMzMhYXMxUjNTMuASMiBhUUFjMyNjU0JzcWFRQGIyIuAx8PLUV2THGCGB7UVhJVT2lygG1DXx42Ro5zS3dHLxEBZDJha080am5UVERCoI6JoUQsIhpPP05PcTNOaWAAAAEACAAAAskC2QAMAFMAsgAAACuyBQMAK7AKM7ECBOmwBzKyAgUKK7NAAgQJKwGwDS+wBNa0AwUAJgQrsAMQsQABK7EJBemyCQAKK7NACQcJK7EOASsAsQIAERKwCTkwMTMRIxUjNSEVIxEBMwG/a0wBmIQBTWD+WwKFZ7tU/hICQv0nAAEANQAAAr8C2QAgAF0AsgEAACuwHTOyAgMAK7QHGQECDSuxBwTpAbAhL7AB1rEABemwAzKwABCxHgErsR0F6bAdELEWASuxDAXpsSIBK7EWHRESshAHETk5OQCxGQERErMEDBAfJBc5MDEzIxEzESU2MzIeAhUUDgEHJz4DNTQmIyIPAREjEQWTXl4BViclEyovHgszLScCGw4OHxMOECRe/v8C2f6sxhYNHDonHCkxD0UBDgoUDBMoCRX+EwG3lAAAAAABADUAAAJ4AtkACwAwALICAAArsAkzsgMDACuwBjMBsAwvsALWsQEF6bAEMrENASsAsQMCERKxBQs5OTAxExUjETMRATMJASMBkl1dAWt4/tcBLG7+/wD//wLZ/o8Bcf7X/lABdgAAAAIACP/qAe0C2QAMABwAQgCyEgAAK7EIBOmyHAMAK7QaAhIcDSuxGgTpAbAdL7AV1rEFBemwBRCxAAErsBsysQ4F6bEeASsAsQIIERKwFTkwMSU1IyIGFRQWMzI+AhMRFAYrASImNTQ+AjsBEQGQmUBSUz8rQCAOXYRiGWKEL1RhOmrWm1pBPlwgMzACGv3+ZImJZEFfNBgBFgAAAAEAHv/oAx4C5QAmAEkAsgQAACuxHwTpsg0DACuxGQTpAbAnL7AJ1rEcBemxKAErALEfBBESsQEmOTmwGRFACgIICQ8REwAUJCUkFzmwDRKxEBI5OTAxJQcnBiMiLgI0PgIzMhc3FzcXBycHNCYjIgYVFBYzMjY1FzcXBwKnUjJBnkl2RCMjRHZJnkEyUkgvd1JGblZfcXFfVm5GUncvmXlTi0t2gXqAdkuLU3lvGbp5c0B9oYuMoX1Ac3m6GQAAAAEAHv+lA5EC5QArAIMAsg8AACuxJwTpsgQAACuxCQTpsicPCiuzQCcACSuyGAMAK7EfBOmyHxgKK7NAHxwJKwGwLC+wEtaxIgXpsCIQsSoBK7AcMrQBBQA8BCuxGwXpsS0BK7EqIhESshgPJzk5ObABEbAMOQCxDwkRErAHObEnBBESsAY5sB8RsQwSOTkwMQEVFBYzMjcXBiMiJicOASMiJjU0PgMzMhYXIy4BIyIGFRQeAjMyNj0BAqMwPywbODJGVmgIK4c/k7ESMkt/UH2hE18PcVN0jBUzaUpTiAFMuE1UGEYgXFEyN9OpMGFqUDV6b0ZRo4YyX2I8gl4xAAAD//n/6QNZAuUALAA4AEkAogCyKgAAK7AmM7EEBOmwEzKyCwMAK7AeM7FCBOmwMzIBsEovsADWsQEF6bABELEIASuxSAXpsEgQsTwBK7EOBemwDhCxGwErsTYF6bA2ELEtASuxIQXpsUsBK7FICBESsQQqOTmwPBGzCwYoESQXObEbDhESsRMmOTmxLTYRErIeGDM5OTkAsQQqERKwKDmwQhFACgABCA4RGBshLTkkFzkwMSc3FBYzMjcmNTQ2MzIWFRQGBxYzMj4CNy4BNTQ2MzIWFRQOAiMiJwYjIiYBNDY1NCYjIgYVFBYBPgE1NC4DIyIOAxUUB1dPMRshZEhRVWI8Mjg+IkJLOQxzV0ZCY0Q4Y3dHY08+PGB7AwIBISEXHC7+lCUtDhQaFQkIEBAMCNoNTVkXdcOzoqmsT6VAIRU1c1IedWk6ZYqdf7tpMjQziAEsBRUGd140LztD/uc0iDs8XzckDQ0jOF49nAAAAAMAHf/pAt0C5QAKABoALACnALIDAAArsSAE6bIIAwArsRAE6bQkGgMIDSu0JAQAHwQrtBMbAwgNK7QTBAAfBCsBsC0vsAbWsR0F6bAdELENASuxAAXpsS4BK7A2GrrC9uzBABUrCg6wKBCwJ8CxFwr5sBjAALMXGCcoLi4uLgGzFxgnKC4uLi6wQBoBsQ0dERKzCAMTIyQXOQCxJCARErAFObEbGhESsgANHTk5ObEQExESsAY5MDEBFAYjIiYQNjMyFgM2NTQmIyIGBzMyFh8BFjMlBhUUFjMyNjcjIiYvAS4CIwLdwKCewsKdoMFqDY52Tncfkx0yDC0VJv6VCY90SXIijSI7DyMDChgOAWGi1tMBVtPU/u0yM4qmTkYlIYA7wiovh6VGPjIvbwkUFAACACT/6QL8AuUALQA3AIMAshoAACuxAATpsiMDACuwEjOxMwTpsAkysw0aIwgrsCczAbA4L7Ah1rE2BemwNhCxMAErsScF6bAnELENASu0DAUAPAQrsAwQsQYBK7EVBemxOQErsTA2ERKxIyk5ObENJxESsQAaOTmxBgwRErASOQCxDQARErUGFSEuMDYkFzkwMSUyPgM1NCYjIgYVIzQ+AjMyFhUUDgIjIi4ENRAzMh4BFRQHHgMnNjU0JiMiBhUUAZI6XTsnEC8eIyBSFisxI1FdKVKQXy9WU0U0HbwtQBvDFT1FOul+HBcwJzsrRV9iNGCSOE1CWC0RxYtRkn5LFS1LZY5VASdEXzblRDJHIQ75MJJKU1t6TgAAAAL/5v/oAkUC5QAXACIAUACyFAAAK7EDBOmyDAMAK7EdBOkBsCMvsAnWsSAF6bAgELEaASuxDwXpsSQBK7EgCRESsQMUOTmwGhGxDAY5OQCxHQMRErQACQ8XGCQXOTAxNx4BMzI2Ny4BNTQ2MzIWFRQOAiMiJiclNjU0JiMiBhUUFjgiYzdDZR90bnVKSWQrUH9MVZgsAe0OLyIjOEvKRklmVCKRV2ODkZZTpIlWZFmgPkVlY1c+O2IAAAAAAgAk/+kCIgLlAAsAIgBPALIUAAArsQAE6bIaAwArsSEE6bQOBhQaDSuxDgTpsx4UGggrAbAjL7AD1rERBemwHiDWEbEdBemxJAErALEGABESsREXOTmwDhGwDDkwMSUyNjU0JiMiBgceAQM2MzIWFRQGIyImNTQ2MzIWFSM0JiMiASdRUFxCO2IQCVZeNoFqg35+eIqLh3NqWEJJnjdURkVVQDReYgFIOn1kbYKhmOrZd2E6UAAAAAEACv/pAxUC8ABCAJkAsisAACuwJzOxOwTpsA4ysBMvsRwE6bITHAors0ATFwkrAbBDL7Au1rE4BemwOBCxPwErsQsF6bAXINYRsRYF6bALELEQASuxIgXpsUQBK7EXOBEStAErMzQ7JBc5sD8RsAA5sBYSswI9QUIkFzmwCxGxAyk5ObAQErQEBxMcJyQXOQCxOysRErApObATEbMCIi4zJBc5MDEBJzcXNxc3FwcnBhUUFjMyETQmIyIGFSM0PgIzMh4DFRQOAiMiJwYjIiY1ND4CNxcOAhUUFjMyNyY1NDcnAQcNQTQ0MzQrXx8nVUuIi0xKNF8nQ0kpQ2xFLhMTL2BEYkRBVXF4FyseFyQSFhRCSTMpHxwSARJNaFFRUVEZnDI2NkRdAR+Jwz9FPFYsFDdZd3c+P2pnOzQ0ensnQzIaEUkPGTgkR1omNksuOh0AAAACABH/8QJUAuUAIAA1AJ4Ash0AACuxIwTpsgAAACuxAQTpshADACuxLgTptCkoHRANK7QpBABDBCsBsDYvsAzWsTQF6bA0ELElASuxGgXpsCsg1hGxEgXpsisSCiuzQCsoCSuxNwErsTQMERKxHyE5ObArEbMPECMdJBc5sCUSsBc5ALEjABESsB85sSgBERK2BgoMGiElNCQXObApEbAXObAuErINEjM5OTkwMTM1MjcmJzceAhc2NRE0NjIWFRQOAgceARUUBiMiJwY3FjMyNTQrATUyNTQmIyIOAhURFBknHDIZKgETIRMBaNZwESERDzRAinJnVDprPUSqqjzHPkYpMxcHWBU8Q1IBKTsbBw8BQF10a1YiNiQOCg5mMn96PS5uLpaMSXE3RhcwLib+ticAAAH/6P/pAqcC2QAnAIwAsh4AACuyCgAAK7EQBOmyEAoKK7NAEA0JK7InAwArtCYEACsEK7ABMgGwKC+wJNaxAwXpsgMkCiuzQAMBCSuyJAMKK7NAJCYJK7ADELAOINYRsQ0F6bANL7EOBemwAxCxEwErsQcF6bEpASuxAw0RErAYObETDhESsAo5ALEmEBESswcYHyEkFzkwMQEVIxUeAhUUBiMiJjUzFDMyNjU0LgIjIg4CByMnNxc+ATc1IzUB4DBRdDJaTE5OVEYkLRcvUzUlVUAuBVVYRTEqgEo0AtlBgAtnhUpji3NYfl1CLVVKLXSflCe9IGiK7yKIQQAAAAABADIAAAIcAuUAGwBeALITAAArsAwzshcDACuxAwTptAcRExcNK7EHBOmzABMXCCsBsBwvsBPWsRIF6bAGMrASELENASuxDAXpsAwQsBsg1hGxAAXpsAAvsRsF6bEdASuxABIRErAXOQAwMQE0JiMiBh0BMzIWHQEjNTQrAREjETQ2MzIWHQEBnkFFUjegZoddqYddhWJghAITRj5FXDCEVuzSov6MAhhccWtWEQAAAAEAH//pA08C5QAqAJcAsh8AACuyIgAAK7EWBOmyAAMAK7ENBOm0GxwiAA0rsRsE6QGwKy+wJdaxEAXpsBAQsRkBK7QdBQA8BCuyGR0KK7NAGRsJK7AdELQfBQARBCuwHy+xLAErsRkQERK0AwoAICIkFzmxHR8RErEJBDk5ALEbFhESsCA5sBwRsRAlOTmwDRKyAwUIOTk5sAARsgQGBzk5OTAxATIWFzcXNxcHJwcuASMiBhUUHgMzMjY9ASM1IREjJwYjIiY1ND4DAWxLbh5DUkgvd1JXE2BRcn0OJDlePGSB3gEwOxdokZS6DyxHewLlOChTeW8ZunlzQFKgiSZNVD8pfmIUUv57YXTUqDFfbE81AAMANQAAAlUC2QAPABUAHwBjALIEAAArsR8E6bIFAwArsRME6bQUHgQFDSuxFATpAbAgL7AE1rEfBemwEzKwHxCxGgErsQAF6bARINYRsQsF6bEhASuxER8RErANOQCxHh8RErAAObAUEbANObATErALOTAxJRQGIyERITIeAhUUBx4BJjQrARUzEzI+ATU0JisBFQJVdmH+twEoPVotFGVGP32StLQvMT4URD/j0F5yAtkkOzsfcC8bVI3o6P6zKzQeOUX7AAD//wAyAJQCFgGGEAYAIAAlAAIAMgAAA3sC2gACAAUAIgCyBQAAK7IDAwArsQAE6QGwBi+xBwErALEABRESsAE5MDETCQElIQHBARYBFf1GA0n+XAKG/h4B4lT9Jv//ADIAAAN7A30QJgeKAAAQBxTRAZoAAAACADIAAAN7AtoAAgAFACIAsgQAACuxAgTpsgUDACsBsAYvsQcBKwCxBQIRErABOTAxJQkBBSEBAuz+6v7rArr8twGkVAHi/h5UAtr//wAyAAADewN2ECcHrgFsAc8QBgeKAAAAAgAyAAACpALaAAIABQAnALIDAAArsgQDACsBsAYvsAPWsQAF6bEHASsAsQQDERKxAgA5OTAxNy0BAxEBhgF7/oVUAnKM4eH9sgLa/pMAAP//ADIAAAKkAwIQJweuAQABWxAGB4wAAP//ADIAAAKkAwIQJweuAZcBWxAnB64AxwFbEAYHjAAA//8AMgAAAqQC2hAnB9EAb/8pEAYHjAAA//8AMgAAAqQC2hAnB64AkAAAEAYHjAAAAAIAMgAAAqQC2gACAAUAJwCyBAAAK7IDAwArAbAGL7AC1rEEBemxBwErALEDBBESsQIAOTkwMQENARMRAQJQ/oUBe1T9jgJO4eECTv0mAW3//wAyAAACpAMCECcHrgEAAVsQBgeRAAD//wAyAAADewLaECYHrgAAEAYHiAAAAAD//wAyAAADewLaECcHrgLUAAAQBgeIAAD//wAyAAADewLaECYHrgAAEAYHigAAAAD//wAyAAADewLaECcHrgLVAAAQBgeKAAD//wAyAAADewN2ECYHrgAAEAYHiwAAAAD//wAyAAADewN2ECcHrgLVAAAQBgeLAAD//wAyAAADQALaECYHrgAAEAcHjACcAAD//wAyAAADQALaECYHjAAAEAcHrgKaAAD//wAyAAADQANOECcHrgDxAacQJweMAJwAABAGB64AAP//ADIAAANAA04QJweuAFUBpxAmB4wAABAHB64CmgAA//8AMgAAAqQDMxAnB64BkQDlECcHrgBuAYwQBgeMAAD//wAyAAADQALaECcHkQCcAAAQBgeuAAD//wAyAAADQALaECYHkQAAEAcHrgKaAAD//wAyAAADQANOECYHrgAAECcHrgJGAacQBweRAJwAAP//ADIAAANAA04QJweuApoAABAnB64BqgGnEAYHkQAA//8AMgAAAqQDLxAnB64AcQDoECcHrgGGAYgQBgeRAAAAAQAyAawBvAMCABwAbgCwBy+wAzO0EAQAHwQrsBcyshAHCiuzQBATCSuxCxsyMgGwHS+wCta0DQUAEQQrsA0QsRIBK7QVBQARBCuwFRCxGgErtAAFABEEK7EeASuxEg0RErAHObAVEbAFObAaErADOQCxEAcRErAFOTAxARQGIyInBiMiJj0BMxUUFjI2PQEzFRQWMjY9ATMBvEIuMyIiMy5CNiIwIjYiMCI2AhwuQicnQi7m5hgiIhjm5hgiIhjmAAAA//8AMgEzASoCQBAmB64AABAHFNEAr/7DAAIAMgGsAY0C2gACAAUAIwCyBQMAK7AEL7QCBAATBCsBsAYvsQcBKwCxBQIRErABOTAxAScHBSETATVWVQED/qWtAeCWljQBLgAAAAABADIBrAEXAtoAAwAiALIDAwArtAIEAAcEKwGwBC+wAta0AAUACQQrsQUBKwAwMQEDIxMBF6o7rQLa/tIBLgAAAQAyAawBFwLaAAMAIgCyAQMAK7QDBAAHBCsBsAQvsADWtAIFAAkEK7EFASsAMDETMxMjMjitOwLa/tIAAQAyAioBkgLaAAsAQACyBQMAK7AAM7ADL7QJBAA3BCsBsAwvsAXWtAYFABsEK7AGELELASu0AAUAGwQrsQ0BK7ELBhESsQMCOTkAMDEBFAYiJjUzFBYyNjUBkmeSZ0Y+WD4C2klnZ0ksPj4sAAAAAAEAMgIqAZIC2gALAEgAsgMDACu0CQQANwQrsgkDCiuzQAkACSuwBTIBsAwvsADWtAsFABsEK7ALELEGASu0BQUAGwQrsQ0BK7EGCxESsQMCOTkAMDETNDYyFhUjNCYiBhUyZ5JnRj5YPgIqSWdnSSw+PiwAAQAyAawA4gMMAAsAQgCwBS+0BgQANwQrsAsvtAAEADcEKwGwDC+wCda0AwUAGwQrsgkDCiuzQAkFCSuwADKxDQErALELBhESsQMCOTkwMRMyFhQGIzUyNjQmIzJJZ2dJLD4+LAMMZ5JnRj5YPgAAAAIAMgGsAZEDDAAJABMATwCwBS+0CgQANwQrsA8vtAAEADcEKwGwFC+wCNa0EgUAGwQrsBIQsQ0BK7QDBQAbBCuxFQErsQ0SERKxBQA5OQCxDwoRErMDBwgCJBc5MDETMhYUBiMiJjQ2EzI2NCYjIgYUFuJHaGhHSWdnSSo/PyosPj4DDGiQaGeSZ/7mPlg+Plg+AP//ADIBrAGdAtoQJwemAIYAABAGB6YAAP//ADIBrgDvAtoQJwfRAIIAABAGB9EAAAABADIBMwCmAacABwAuALAHL7QDBAASBCu0AwQAEgQrAbAIL7AB1rQFBQAaBCu0BQUAGgQrsQkBKwAwMRI0NjIWFAYiMiIwIiIwAVUwIiIwIgAAAAABADIBvgFeAfkAAwAoALAAL7QBBAAfBCu0AQQAHwQrAbAEL7EAASu0AwUABwQrsQUBKwAwMRM1IRUyASwBvjs7AAAAAAEAMgGuAV4C2gALAFIAsgADACuwCS+wBDO0CgQAHwQrsAIysgkKCiuzQAkHCSsBsAwvsAfWsAAytAYFABEEK7ABMrIGBwors0AGBAkrsgcGCiuzQAcJCSuxDQErADAxEzMVMxUjFSM1IzUzqjt5eTt4eALaeTt4eDsAAAABADIBrgFeAtoABwBGALIHAwArtAYEAB8EK7ABMrIGBwors0AGBAkrAbAIL7AE1rQDBQARBCuyAwQKK7NAAwEJK7IEAwors0AEBgkrsQkBKwAwMQEVIxUjNSM1AV55O3gC2jvx8TsA//8AMgAABF8DAhAnB6cDSAAoEAYHiAAA//8AMgAAA3sDAhAnB6cCXgAoEAYHigAA//8AMgAAAvgC2hAnB6cB4QAAEAYHjAAA//8AMgAAA8IDAhAnB6cCqwAoEAYHkQAAAAEAMgAAA3sC2gAFACEAsgEAACuyAgMAK7AAMwGwBi+xBwErALECARESsAQ5MDEJAjMJAQN7/lz+W18BRgFGAtr9JgLa/coCNgAAAP//ADIAAAN7A30QJge4AAAQBxTRAZoAAAABADIAAAN7AtoABQAhALIAAAArsAIzsgEDACsBsAYvsQcBKwCxAQARErAEOTAxMwkBIwkBMgGkAaVf/rr+ugLa/SYCNv3KAP//ADIAAAN7A3YQJweuAWoBzxAGB7gAAAABADIAAAKkAtoABQAWALICAAArsgADACsBsAYvsQcBKwAwMRMJATUJATICcv2OAc/+MQLa/pP+k1oBEwETAAD//wAyAAACpAMCECcHrgEBAVsQBge6AAD//wAyAAACpAMCECYHugAAECcHrgGXAVsQBweuAMcBW///ADIAAAKkAtoQJge6AAAQBwfRAG//Kf//ADIAAAKkAtoQJweuAK0AABAGB7oAAAABADIAAAKkAtoABQAWALIAAAArsgIDACsBsAYvsQcBKwAwMSEJARUJAQKk/Y4Ccv4xAc8BbQFtWv7t/u0AAAD//wAyAAACpAMCECcHrgECAVsQBge/AAD//wAyAAADewLaECYHrgAAEAYHtgAAAAD//wAyAAADewLaECcHrgLVAAAQBge2AAD//wAyAAADewLaECYHrgAAEAYHuAAAAAD//wAyAAADewLaECcHrgLVAAAQBge4AAD//wAyAAADewN2ECcHrgFrAc8QBgfDAAD//wAyAAADewN2ECcHrgFqAc8QBgfEAAD//wAyAAACpALaECYHrgAAEAYHugAAAAD//wAyAAADQALaECcHrgKaAAAQBge6AAD//wAyAAACpANOECYHrgAAECYHugAAEAcHrgBbAacAAP//ADIAAANAA04QJge6AAAQJweuApoAABAHB64AWwGn//8AMgAAA0AC2hAmB64AABAHB78AnAAA//8AMgAAAqQC2hAnB64B/gAAEAYHvwAA//8AMgAAA0ADThAmB8sAABAHB64CRgGn//8AMgAAAqQDThAmB8wAABAHB64ByAGn//8AMgAAAqQDEhAnB64BbAFrECcHrgCcAWsQBge/AAAAAQAyAawBVAMCAAUAIgABsAYvsAHWtAMFAAcEK7EHASuxAwERErIAAgQ5OTkAMDEBLQEVBxcBVP7eASLS0gGsq6s1dncAAAAAAQAyAa4AbQLaAAMAKQCyAAMAK7QDBAAHBCsBsAQvsAPWtAIFABEEK7QCBQARBCuxBQErADAxEzMRIzI7OwLa/tQAAAABADIBbQEaAtoAEgBUALIJAwArsAMvtA0EABMEK7IDDQors0ADCAkrsBEyAbATL7AI1rQHBQARBCuwCjKwBxCxEgErtBEFABEEK7EUASuxEgcRErANOQCxDQMRErALOTAxEzQmIyIGHQEjETMVNjMyFh0BI+QhFSAmNjYgNCY4NgIjHBcwKJEBbYArMCHHAAABADIAAAK0AtoADwA5ALIEAAArsQwE6bIHAwArsAAzAbAQL7AG1rEJBemwCRCxDgErsQEF6bERASuxDgkRErEEAzk5ADAxAREUBiImNREzERQWMjY1EQK0xfjFVJWwlQLa/kp2rq52Abb+SlN9fVMBtgAA//8AMgAAArQDfRAnFNEBNgAAEAYH1QAAAAEAMgAAArQC2gAPADkAsgAAACuwBzOyBAMAK7EMBOkBsBAvsADWsQ8F6bAPELEIASuxBwXpsREBK7EIDxESsQQDOTkAMDEzETQ2MhYVESMRNCYiBhURMsX4xVSVsJUBtnaurnb+SgG2U319U/5KAP//ADIAAAK0A3YQJweuAQcBzxAGB9UAAAABADIAAAK2AtoADwAvALIHAAArsQgE6bIAAwArsQ8E6QGwEC+wDNaxBAXpsREBKwCxDwgRErEEAzk5MDETITIWEAYjITUhMjY0JiMhMgFBhb6+hf6/AUFii4ti/r8C2tb+0tZUpeil//8AMgAAArYDdhAnB64BBwHPEAYH1wAA//8AMgAAArYDdhAnB64BbQHPECcHrgCdAc8QBgfXAAD//wAyAAACtgLaECcH0QBk/ykQBgfXAAD//wAyAAACtgLaECcHrgDWAAAQBgfXAAAAAQAyAAACtgLaAA8ALwCyAQAAK7EOBOmyBgMAK7EJBOkBsBAvsATWsQwF6bERASsAsQkOERKxBAM5OTAxKQEiJhA2MyEVISIGFBYzIQK2/r+Fvr6FAUH+v2KLi2IBQdYBLtZUpeilAP//ADIAAAK2A3YQJgfcAAAQBweuATkBz///ADIAAANgAtoQJgeuAAAQBwfTAKwAAP//ADIAAANeAtoQJweuArgAABAGB9MAAP//ADIAAANeAtoQJwfVAKoAABAGB64AAP//ADIAAANeAtoQJgfVAAAQBweuArgAAP//ADIAAANeA3YQJweuAbEBzxAnB9UAqgAAEAYHrgAA//8AMgAAA14DdhAnB64BDQHPEAYH4QAA//8AMgAAArYC2hAmB64AABAGB9cAAAAA//8AMgAAA2IC2hAmB9cAABAHB64CvAAA//8AMgAAArYDdhAnB64BBwHPEAYH5AAA//8AMgAAA2IDdhAnB64BBwHPEAYH5QAA//8AMgAAA2IC2hAnB9wArAAAEAYHrgAA//8AMgAAArYC2hAmB9wAABAHB64CEAAA//8AMgAAA2IDdhAmB64AABAnB9wArAAAEAcHrgGzAc///wAyAAACtgN2ECcHrgIQAAAQJgfcAAAQBweuAQcBz///ADIAAANhAtoQJwfcAKsAABAmB64AoRAGB64AYQAAAAEAMgFtAasDAgAPADYAsgoCACu0BwQANwQrsAIvtA8EADcEKwGwEC+wBda0DQUAGwQrsREBKwCxCg8RErEEBTk5MDEBFSMiJjQ2OwEVIyIGFBYzAarSRWFhRdPTLDU1LAGzRnWqdkZPbE4A//8AMgAAAyUC2hAnB9ECuAAAEAYH0wAA//8AMgAAAyUC2hAnB9ECuAAAEAYH1QAA//8AMgAAAyUC2hAnB9ECuAAAEAYH1wAA//8AMgAAAyUC2hAmB9wAABAHB9ECuAAAAAEAMgAAAh4C2gAXAE8AsgwAACuyBwMAK7EQBOm0ARYMBw0rsQEE6QGwGC+wBNa0EwUAPAQrsBMQsQwBK7QLBQA8BCuxGQErsQwTERKxBwA5OQCxEBYRErAEOTAxASMiJjU0NjMyFhURIxE0JiMiBhUUFjsBAZSAYoCRZWKUUl5GRV9gRGwBQX9SUHiTU/4MAeA6bkI0NUr//wAyAAACHgN9ECYH9AAAEAcU0QDxAAAAAQAyAAACHgLaABcATwCyDQAAK7IRAwArsQgE6bQAAQ0RDSuxAATpAbAYL7AN1rQMBQA8BCuwDBCxBQErtBQFADwEK7EZASuxBQwRErEAETk5ALEIARESsBQ5MDETNTMyNjU0JiMiBhURIxE0NjMyFhUUBiO8bERgX0VGXlKUYmWRgGIBQVJKNTRCbjr+IAH0U5N4UFJ/AP//ADIAAAIeA3YQJweuALwBzxAGB/QAAAABADIAAAIeAtoAFwBPALIRAAArsQgE6bIMAwArtBcCEQwNK7EXBOkBsBgvsBTWtAUFADwEK7AFELELASu0DgUAPAQrsRkBK7ELBRESsQAROTkAsQIIERKwFDkwMQEVIyIGFRQWMzI2NREzERQGIyImNTQ2MwGUbERgX0VGXlKUYmWRgGIBmVJKNTRCbjoB4P4MU5N4UFJ///8AMgAAAjADdhAnB64BigHPEAYH9gAA//8AMgAAApcDeBAnB64B8QHRECcHrgEhAdEQBgf2AAAAAQAyAAACHgLaABcATwCyBwAAK7EQBOmyCwMAK7QAFwcLDSuxAATpAbAYL7AK1rQNBQA8BCuwDRCxEwErtAQFADwEK7EZASuxEw0RErEHADk5ALEXEBESsAQ5MDETMzIWFRQGIyImNREzERQWMzI2NTQmKwG8gGKAkWVilFJeRkVfYERsAZl/UlB4k1MB9P4gOm5CNDVKAP//ADIAAAIpA3YQJweuAAABzxAGB/kLAP//ADIAAAKcAtoQJgeuAAAQBgfyfgAAAP//ADIAAALKAtoQJweuAiQAABAGB/IAAP//ADIAAALKAtoQJgeuAAAQBwf0AKwAAP//ADIAAAKcAtoQJgf0AAAQBweuAfYAAP//ADIAAALKA3YQJweuAWgBzxAGB/0AAP//ADIAAAKcA3YQJweuALwBzxAGB/4AAP//ADIAAAKcAtoQJgeuAAAQBgf2fgAAAP//ADIAAALJAtoQJweuAiMAABAGB/YAAP//ADIAAAKtA3YQJweuAgcBzxAGCAEAAP//ADIAAALJA3YQJweuAYkBzxAGCAIAAP//ADIAAALKAtoQJgeuAAAQBwf5AKwAAP//ADIAAAKcAtoQJweuAfYAABAGB/kAAP//ADIAAALKA3YQJweuAJwBzxAGCAUAAP//ADIAAAKsA3YQJweuAAABzxAGCAYQAP//ADIAAALJAtoQJgeuAKEQJgeuAGEQBwf5AKsAAAAAAAEAMgFsATcC2gAVAFoAsgoDACuyFQEAK7QABAAfBCuwBi+0DwQAHwQrAbAWL7AJ1rQMBQARBCuwDBCxEgErtAMFABEEK7ISAwors0ASFQkrsRcBK7ESDBESsAY5ALEVDxESsAM5MDETMzIVFAYjIiY1ETMVFBYzMjY0JisBgiuKUjgzSDgjICMvLyMrAkxwNjo3KAEP9xwjHjQeAAEAMgFsATcC2gAVAFoAsgsDACuyAgEAK7QVBAAfBCuwEC+0BwQAHwQrAbAWL7AT1rQFBQARBCuyBRMKK7NABQEJK7AFELEKASu0DQUAEQQrsRcBK7EKBRESsBA5ALECBxESsBM5MDETFSMiBhQWMzI2PQEzERQGIyImNTQz5ysjLy8jICM4SDM4UooCTDgeNB4jHPf+8Sg3OjZw//8AMgAAApIC2hAnB9ECJQAAEAYH8gAA//8AMgAAApIC2hAnB9ECJQAAEAYH9AAA//8AMgAAApIC2hAnB9ECJQAAEAYH9gAA//8AMgAAAlkC2hAnB9EB7AAAEAYH+QAAAAEAMgAAAh4C2gARAEUAsggAACuyAwMAK7EMBOmyDAMKK7NADBEJKwGwEi+wEda0EAUAPAQrsBAQsQgBK7QHBQA8BCuxEwErsQgQERKwAzkAMDETNDYzMhYVESMRNCYjIgYdASMykWVilFJeRkVfUgISUHiTU/4MAeA6bkI0MgD//wAyAAACHgN9ECYIEgAAEAcU0QDuAAAAAQAyAAACHgLaABEARQCyCwAAK7IPAwArsQYE6bIGDwors0AGAQkrAbASL7AL1rQKBQA8BCuwChCxAgErtAEFADwEK7ETASuxAgoRErAPOQAwMQEVIzU0JiMiBhURIxE0NjMyFgIeUl9FRl5SlGJlkQISMjI0Qm46/iAB9FOTeP//ADIAAAIeA3YQJweuALwBzxAGCBIAAAABADIAAAIeAtoAEQBFALIPAAArsQYE6bIGDwors0AGAQkrsgoDACsBsBIvsADWtAMFADwEK7ADELEJASu0DAUAPAQrsRMBK7EJAxESsA85ADAxNzUzFRQWMzI2NREzERQGIyImMlJfRUZeUpRiZZHIMjI0Qm46AeD+DFOTeAAA//8AMgAAAjADdhAnB64BigHPEAYIFAAA//8AMgAAApcDeBAnB64B8QHRECcHrgEhAdEQBggUAAAAAQAyAAACHgLaABEARQCyAwAAK7EMBOmyDAMKK7NADBEJK7IHAwArAbASL7AG1rQJBQA8BCuwCRCxDwErtAAFADwEK7ETASuxDwkRErADOQAwMSUUBiMiJjURMxEUFjMyNj0BMwIekWVilFJeRkVfUshQeJNTAfT+IDpuQjQyAP//ADIAAAIuA3YQJweuAAABzxAGCBcQAP//ADIAAAIuAtoQJgeuAAAQBggQEAAAAP//ADIAAALJAtoQJweuAiMAABAGCBAAAP//ADIAAALJAtoQJgeuAAAQBwgSAKsAAP//ADIAAAIuAtoQJweuAYgAABAGCBIAAP//ADIAAALJA3YQJweuAWcBzxAnCBIAqwAAEAYHrgAA//8AMgAAAi4DdhAnB64AvAHPECYIEgAAEAcHrgGIAAD//wAyAAACLwLaECYHrgAAEAYIFBEAAAD//wAyAAACyQLaECcHrgIjAAAQBggUAAD//wAyAAACQQN2ECcHrgGbAc8QJggUEQAQBgeuAAAAAP//ADIAAALJA3YQJweuAYoBzxAmCBQAABAHB64CIwAA//8AMgAAAskC2hAmB64AABAHCBcAqwAA//8AMgAAAi8C2hAnB64BiQAAEAYIFwAA//8AMgAAAskDdhAnB64AmwHPECcIFwCrAAAQBgeuAAD//wAyAAACPwN2ECcHrgAAAc8QJggXEAAQBweuAZkAAP//ADIAAALJAtoQJgeuAKEQJgeuAGEQBwgXAKsAAAAAAAEAMgFsATcC2gAPAEYAsgcDACuwAy+0DAQAHwQrsgwDCiuzQAwACSsBsBAvsAbWtAkFABEEK7AJELEPASu0AAUAEQQrsREBK7EPCRESsAM5ADAxARQGIyImNREzFRQWMzI2NQE3UjgzSDgjICMvAdw2OjcoAQ/3HCMeGgABADIBbAE3AtoADwBGALIIAwArsA0vtAQEAB8EK7IEDQors0AEAAkrAbAQL7AA1rQBBQARBCuwARCxBwErtAoFABEEK7ERASuxBwERErANOQAwMRMzFBYzMjY9ATMRFAYjIiYyOC8jICM4SDM4UgHcGh4jHPf+8Sg3OgAAAQAyAAACHgLaAAUALwCyAgAAK7IFAwArsQQE6QGwBi+wAta0AQUAPAQrsgIBCiuzQAIECSuxBwErADAxAREjESE1Ah5S/mYC2v0mAohSAP//ADIAAAIeA30QJggsAAAQBxTRANwAAAABADIAAAIeAtoABQAvALIFAAArsgADACuxAwTpAbAGL7AF1rQEBQA8BCuyBAUKK7NABAIJK7EHASsAMDETIRUhESMyAez+ZlIC2lL9eAAA//8AMgAAAh4DdhAnB64AvAHPEAYILAAAAAEAMgAAAh4C2gAFAC8AsgEAACuxAgTpsgQDACsBsAYvsAPWtAAFADwEK7IDAAors0ADAQkrsQcBKwAwMSkBNSERMwIe/hQBmlJSAogAAAD//wAyAAACMAN2ECcHrgGKAc8QBgguAAD//wAyAAAClwN4ECcHrgHxAdEQJweuASEB0RAGCC4AAAABADIAAAIeAtoABQAvALIAAAArsQME6bIBAwArAbAGL7AA1rQDBQA8BCuyAwAKK7NAAwUJK7EHASsAMDEzETMRIRUyUgGaAtr9eFL//wAyAAACLgN2ECcHrgAAAc8QBggxEAD//wAyAAACHgLaECYHrgAAEAYIKgAAAAD//wAyAAACyQLaECcHrgIjAAAQBggqAAD//wAyAAACyQLaECYHrgAAEAcILACrAAD//wAyAAACHgLaECcHrgF4AAAQBggsAAD//wAyAAACyQN2ECYHrgAAEAcILQCrAAD//wAyAAACHgN2ECcHrgF4AAAQJggsAAAQBweuAO4Bz///ADIAAAIeAtoQJgeuAAAQBgguAAAAAP//ADIAAALJAtoQJweuAiMAABAGCC4AAP//ADIAAAIwA3YQJweuAYoBzxAmB64AABAGCC4AAAAA//8AMgAAAskDdhAnB64BigHPECcHrgIjAAAQBgguAAD//wAyAAACyQLaECYHrgAAEAcIMQCrAAD//wAyAAACHgLaECcHrgF4AAAQBggxAAD//wAyAAACyQN2ECcHrgCbAc8QJgeuAAAQBwgxAKsAAP//ADIAAAIuA3YQJweuAAABzxAnB64BiAAAEAYIMRAA//8AMgAAAskC2hAmB64AoRAmB64AYRAHCDEAqwAAAAAAAQAyAW0BKALaAAUAMACyAQMAK7AAL7QDBAAfBCsBsAYvsADWtAMFABEEK7IDAAors0ADBQkrsQcBKwAwMRMRMxEzFTI7uwFtAW3+zToAAAABADIBcADiAtAACwBCALAAL7QLBAA3BCuwBi+0BQQANwQrAbAML7AD1rQJBQAbBCuyCQMKK7NACQAJK7AFMrENASsAsQYLERKxAwI5OTAxEyImNDYzFSIGFBYz4klnZ0ksPj4sAXBnkmdGPlg+AAAAAQAyAW0BKALaAAUAMACyBAMAK7ABL7QCBAAfBCsBsAYvsAPWtAAFABEEK7IDAAors0ADAQkrsQcBKwAwMQEjNTMRMwEo9rs7AW06ATMAAAABADIBbQEZAtoAGQBpALIPAwArtAgEABMEK7IIDwors0AIDQkrsAAvtBcEABMEKwGwGi+wDdawADK0DAUAEQQrtBcFABsEK7AMELEGASu0EgUAEQQrsBgysRsBK7EGFxESswQIDxUkFzkAsQgXERKxBBI5OTAxEzQ+AzU0IyIOAQcjNjMyFhUUDgIVMxUyJTU2JUIaHgYBNANyMkAzPjOkAW0oQSsmLxs3GRoWezouJkYpLhAyAAAAAQAyAAACAALaABwAWACyAAAAK7EaBOmyEAMAK7ELBOmyCxAKK7NACw4JKwGwHS+wDtawADKxDQXpsA0QsQgBK7ETBemwGzKxHgErsQgNERKzBRAYGiQXOQCxCxoRErEFEzk5MDEzND4FNTQmIyIHIzYzMhYVFA4EFSEVMilBT1BBKVA8hQpYB+NlfjNOWU4zAVw7Y0U8ODlMLDlJpvZ0XDRmS0s4OxdQAAAAAAEAMgAAApYB7AAXAEYAshQAACuxBQTpsAwvsQ0E6QGwGC+wF9a0AgUAPAQrsAIQsQgBK7QRBQA8BCuxGQErsQgCERKwFDkAsQwFERKxABE5OTAxEzMVFBYzMjY1NCYjITUhMhYVFAYjIiY1/VJKNTRCbjr+lgF+U5N4UFJ/AWJsRGBfRUZeUpRiZZGAYgAA//8AMgAAApYCkBAmCEkAABAHFNEA+/8TAAEAMgAAApYB7AAXAEYAsgQAACuxEwTpsA0vsQoE6QGwGC+wB9a0EAUAPAQrsBAQsRYBK7QBBQA8BCuxGQErsRYQERKwBDkAsQ0TERKxBwA5OTAxARUUBiMiJjU0NjMhFSEiBhUUFjMyNj0BAct/UlB4k1MBfv6WOm5CNDVKAWKAYoCRZWKUUl5GRV9gRGwA//8AMgAAApYCiBAmCEkAABAHB64A0wDhAAEAMgAAApYB7AAXAEYAsgsAACuxDATpsBMvsQQE6QGwGC+wANa0FwUAPAQrsBcQsRABK7QHBQA8BCuxGQErsRAXERKwBDkAsRMMERKxBwA5OTAxNzU0NjMyFhUUBiMhNSEyNjU0JiMiBh0B/X9SUHiTU/6CAWo6bkI0NUqKgGKAkWVilFJeRkVfYERsAAAA//8AMgAAApYCiBAmCEsAABAHB64BZADh//8AMgAAApYCiBAmCEsAABAnB64BygDhEAcHrgD6AOEAAQAyAAAClgHsABcARgCyDgAAK7ELBOmwBS+xFATpAbAYL7AR1rQIBQA8BCuwCBCxAQErtAAFADwEK7EZASuxAQgRErAUOQCxBQsRErEAETk5MDElIzU0JiMiBhUUFjMhFSEiJjU0NjMyFhUBy1JKNTRCbjoBav6CU5N4UFJ/imxEYF9FRl5SlGJlkYBiAAD//wAyAAAClgKIECcHrgCMAOEQBghOAAD//wAyAAADMgH9ECYHrgBWEAcIRwCcAAD//wAyAAADCgH9ECcHrgJkAFYQBghHAAD//wAyAAADCgHsECYHrgBFEAYITnQAAAD//wAyAAAClgHsECcHrgHwAEUQBghOAAD//wAyAAADCgKIECcHrgEAAOEQBghSAAD//wAyAAAClgKIECcHrgCMAOEQBghTAAD//wAyAAAClgKIECcHrgD2AOEQJweuACYA4RAGCE4AAAABADIBbAGgAnEAFQBTALANL7QKBAAfBCuwBS+0EwQAHwQrsgUTCiuzQAUBCSsBsBYvsBDWtAcFABEEK7AHELEBASu0AAUAEQQrsRcBK7EBBxESsBM5ALEFChESsBA5MDEBIzU0JiIGFRQWOwEVISImNTQ2MzIVARI4HjQeIxz3/vEoNzo2cAG8KyMvLyMgIzhIMzhSigAAAAEAMgFtAZIC2gAPAEAAsg8DACuwBzOwDC+0BAQAHwQrAbAQL7AO1rQBBQARBCuwARCxBgErtAkFABEEK7ERASuxBgERErELDDk5ADAxExUUFjI2PQEzFRQGIiY9AWhIZEg2Z5JnAtq9MkhIMr29SWdnSb0AAQAyAWwBoAJxABUAUwCwCi+0CwQAHwQrsBIvtAMEAB8EK7ISAwors0ASAAkrAbAWL7AA1rQVBQARBCuwFRCxDwErtAYFABEEK7EXASuxDxURErADOQCxEgsRErAGOTAxEzU0MzIWFRQGIyE1MzI2NTQmIgYdAcBwNjo3KP7x9xwjHjQeAbwrilI4M0g4IyAjLy8jKwAAAAABADIAAAKWAewAEQA5ALIBAAArsQIE6bAKL7ELBOkBsBIvsAbWtA8FADwEK7IGDwors0AGAQkrsRMBKwCxCgIRErAPOTAxISM1MzI2NTQmIyE1ITIWFRQGAc4yMjRCbjr+lgF+U5N4Ul9FRl5SlGJlkQAA//8AMgAAApYCjxAmCFwAABAHFNEA/f8SAAEAMgAAApYB7AARADkAsgAAACuxDwTpsAkvsQYE6QGwEi+wA9a0DAUAPAQrsgwDCiuzQAwRCSuxEwErALEJDxESsAM5MDEzIiY1NDYzIRUhIgYVFBY7ARX6UHiTUwF+/pY6bkI0MpFlYpRSXkZFX1IAAAD//wAyAAAClgKIECYIXAAAEAcHrgDwAOEAAQAyAAAClgHsABEAOQCyBwAAK7EIBOmwEC+xEQTpAbASL7AM1rQDBQA8BCuyDAMKK7NADBEJK7ETASsAsRAIERKwAzkwMQEyFhUUBiMhNSEyNjU0JisBNQHOUHiTU/6CAWo6bkI0MgHskWVilFJeRkVfUv//ADIAAAKWAogQJweuATIA4RAGCF4AAP//ADIAAAKWAogQJweuAZgA4RAnB64AyADhEAYIXgAAAAEAMgAAApYB7AARADkAsgwAACuxCQTpsAMvsQAE6QGwEi+wD9a0BgUAPAQrsgYPCiuzQAYBCSuxEwErALEDCRESsA85MDETMxUjIgYVFBYzIRUhIiY1NDb6MjI0Qm46AWr+glOTeAHsUl9FRl5SlGJlkQD//wAyAAAClgKIECcHrgDwAOEQBghhAAD//wAyAAADMgH9ECcIWgCcAAAQBgeuAFb//wAyAAADCgH9ECcHrgJkAFYQBghaAAD//wAyAAADCgH9ECYIXHQAEAYHrgBWAAD//wAyAAADMgH9ECYIXAAAEAcHrgKMAFb//wAyAAADCgKIECcHrgFkAOEQBghlAAD//wAyAAADMgKIECcHrgDwAOEQBghmAAD//wAyAAAClgH9ECYHrgBWEAYIXgAAAAD//wAyAAADCgH9ECYIXgAAEAcHrgJkAFb//wAyAAAClgKIECcHrgEyAOEQBghpAAD//wAyAAADCgKIECcHrgEyAOEQBghqAAD//wAyAAADCgH9ECYIYXQAEAYHrgBWAAD//wAyAAAClgH9ECYIYQAAEAcHrgHwAFb//wAyAAADCgKIECYHrgBWECYIYXQAEAcHrgEyAOEAAP//ADIAAAKWAogQJweuAfAAVhAmCGEAABAHB64AvgDhAAEAMgFsAaACcQAPAD0AsAovtAcEAB8EK7ABL7QABAAfBCsBsBAvsA3WtAQFABEEK7IEDQors0AEAAkrsREBKwCxAQcRErANOTAxExUiBhUUFjsBFSEiJjU0NqIaHiMc9/7xKDc6AnE4LyMgIzhIMzhSAAAAAQAAAW0BBgLaAAkALwCyBwMAKwGwCi+wBNawBjK0AgUACAQrsAgysQsBK7ECBBEStAABBQcJJBc5ADAxAQcXFSU3JyUVBwEGkpL++p+fAQaSAiRMNjViVVdfNDQAAAAAAQAyAAACPgLaAAkAFgCyAwAAK7IHAwArAbAKL7ELASsAMDEBDQEVLQMVBQI+/tABMP30AVz+pAIM/tABbZ50W8KrsL1ZcQAAAQAyAAABxgLaAA4AMwCyAAAAK7IHAwArtAEMAAcNK7EBBOkBsA8vsAbWsQkF6bAJELEAASuxDgXpsRABKwAwMSERIi4CPQEzFRQWOwERAXJBb1s1VINVaAFFHTxoRY+jSlj+awAAAP//ADIAAAHZA34QJgh2AAAQBxTRAV4AAQABADIAAAHGAtoADgAzALIBAAArsgcDACu0DgMBBw0rsQ4E6QGwDy+wAdaxAAXpsAAQsQYBK7EJBemxEAErADAxMyMRMzI2PQEzFRQOAiOGVGhVg1Q1W29BAZVYSqOPRWg8HQD//wAyAAAB1wN2ECYIdgAAEAcHrgExAc8AAQAyAAABxgLaAA4AMwCyCAAAK7IAAwArtAMOCAANK7EDBOkBsA8vsAjWsQcF6bAHELEOASuxAgXpsRABKwAwMQEzESMiBh0BIzU0PgIzAXJUaFWDVDVbb0EC2v5rWEqjj0VoPB0AAP//ADIAAAHWA3YQJweuATABzxAGCHgAAP//ADIAAAI+A3YQJweuAZgBzxAnB64AyAHPEAYIeAAAAAEAMgAAAcYC2gAOADMAsggAACuyDgMAK7QMAQgODSuxDATpAbAPL7AN1rEBBemwARCxCAErsQcF6bEQASsAMDETETIeAh0BIzU0JisBEYZBb1s1VINVaALa/rsdPGhFj6NKWAGVAAD//wAyAAAB1gN2ECcHrgAAAc8QBgh7EAD//wAy//0COgLXECYIdHT9EAYHrgAAAAD//wAyAAACYgLaECYIdAAAEAcHrgG8AAD//wAyAAACYQLaECcIdgCbAAAQBgeuAAD//wAyAAACOgLaECYIdgAAEAcHrgGUAAD//wAyAAACcgN2ECYHrgAAECcIdgCbAAAQBweuAcwBz///ADIAAAI6A3YQJweuAZQAABAmCHYAABAHB64BMQHP//8AMgAAAjoC2hAmB64AABAGCHh0AAAA//8AMgAAAmIC2hAnB64BvAAAEAYIeAAA//8AMgAAAksDdhAmB64AABAnB64BpQHPEAYIeHYAAAD//wAyAAACcgN2ECcHrgHMAAAQJweuATABzxAGCHgAAP//ADIAAAJhAtoQJgeuAAAQBwh7AJsAAP//ADIAAAI6AtoQJweuAZQAABAGCHsAAP//ADIAAAJhA3YQJweuAIsBzxAGCIcAAP//ADIAAAJKA3YQJweuAAABzxAGCIgQAP//ADIAAAJhAtoQJwh7AJsAABAmB64AoRAGB64AYQAAAAEAMgFtAQMC2gAMADMAsgwDACuwCi+0AQQAEwQrAbANL7AL1rQBBQARBCuwARCxBgErtAUFABEEK7EOASsAMDETFTIWHQEjNTQmKwE1Y0RcMTorOwLaokFDR1ElJdIAAAEAMgFtATsC2gAmAKQAshIDACu0GAQAEwQrshgSCiuzQBgUCSuwIy+0BQQAEwQrsgUjCiuzQAUmCSsBsCcvsCbWsA8ytAAFABEEK7AaMrAAELEIASuwFTK0IAUAEQQrsBQysSgBK7A2GrrtnMKzABUrCg6wDBCwC8CxHAj5sB3AALMLDBwdLi4uLgGzCwwcHS4uLi6wQBoBsQgAERKyERIjOTk5ALEYBRESsQ8gOTkwMRMeAzMyNjU0Ji8BLgE1NDYyFhUjLgEiBhUUHwEeARUUBiMiJidqAgYPHhcjKhgcMjwvTXZGOAEpQi0+NDMsSj9BPQIB4BARFgodGBEVCQ8OKyguOTcxGhwcFyIODw8qJTE6ODsAAAABADIBbQEDAtoADAAzALIAAwArsAMvtAwEABMEKwGwDS+wCNa0BwUAEQQrsAcQsQwBK7QCBQARBCuxDgErADAxEzMVIyIGHQEjNTQ2M9IxOys6MVxEAtrSJSVRR0NBAAABADIBbQGYAtoACwAlALIEAwArsAAvtAkEAB8EKwGwDC+wA9a0BgUAEQQrsQ0BKwAwMQEiJj0BMxUUFjsBFQE7bZw2gl1RAW2bbmRYXYI2AAIAMgFXAQkC2gAQABgAcwCyBAMAK7ICAQArtAYEAB8EK7IIAQArsAwvtBcEABMEK7ARL7QABAATBCsBsBkvsAPWtAYFABEEK7MPBgMIK7QUBQARBCuwBhCxEQErtAkFABEEK7EaASuxERQRErEMADk5ALERFxESsA85sAARsAk5MDETJisBNTMVMhYVFAYjIiY1NBcOARUUFjMyyxREQTdGWjQ0Hyx8NBwWEyUB7yPIkjlDNUApKkAnARARDBIAAAIAMgFXAQkC2gAQABkAfQCyDAMAK7IPAQArtAsEAB8EK7IJAQArsAUvtBMEABMEK7ARL7QABAATBCsBsBovsAjWtBEFABEEK7ARELELASu0DgUAEQQrswIOCwgrtBYFABEEK7AWL7QCBQARBCuxGwErsRYRERKxBQA5OQCxERMRErACObAAEbAIOTAxExYVFAYjIiY1NDYzNTMVIyIHFjMyNjU0LgFwdSwfNDRaRjdBRBsCJRMWByUB7wVAKilANUM5kshPQBIMCw0KAAMAMgEBASkDRgAHAA8AHAB3ALIcAwArsAcvsQME6bAaL7QRBAATBCuwDy+xCwTpAbAdL7Ab1rQRBQARBCuzERsJDiuxDQXpsBEQsRYBK7QVBQARBCuzERYBDiuxBQXpsR4BK7ERGxESswsODwokFzmxFRYRErMDBgcCJBc5ALEaAxESsBU5MDESNDYyFhQGIgI0NjIWFAYiFxUyFh0BIzU0JisBNdIaJBkZJLoaJBkZJChEXDE6KzsBGyQZGSQaAgckGhokGhSiQUNHUSUl0v//ADIAAAPAA0YQJgiSAAAQBwe/ARwAAP//ADIAAAPKA0YQJgiSAAAQBwfcARQAAP//ADIAAAM2A0YQJgiSAAAQBwf5ARgAAP//ADIAAAM2A0YQJgiSAAAQBwgXARgAAAABADIAAAMMAtoAHwBjALIMAAArsQME6bIcAwArsRME6QGwIC+wGNa0FwUAPAQrsBcQsQ8BK7QABQA8BCuwABCxBgErtAkFADwEK7EhASuxDxcRErAcObEGABESsAw5ALETAxEStQcIDxcYHyQXOTAxJRQWMzI2PQEzFRQGIyImNRE0JiMiBh0BIzU0NjMyFhUByEU0MkdSfk1Mf0U0MkdSfk1Mf/o7bVQ2kaVOeoxQAQQ7bVQ2kaVOeoxQAAEAMgAAAwwC2gAfAGEAshQAACuxHQTpsgQDACuxDQTpAbAgL7AX1rQaBQA8BCuwGhCxAAErtBEFADwEK7ARELEJASu0CAUAPAQrsSEBK7EAGhESsBQ5sQkRERKwBDkAsQ0dERKzAQgRGCQXOTAxJRE0NjMyFh0BIzU0JiMiBhURFAYjIiY9ATMVFBYzMjYBdn9MTX5SRzI0RX9MTX5SRzI0RfoBBFCMek6lkTZUbTv+/FCMek6lkTZUbQD//wAyAAADDAN2ECYImAAAEAcHrgHWAc8AAQAyAAADJAHiACsAlgCyAQAAK7AaM7EABOmwDTKwIS+wEzOxBgTpsBQyAbAsL7AD1rEkBemyJAMKK7NAJAEJK7AkELEQASuxFwXpshAXCiuzQBAUCSuxLQErsDYausFs8pcAFSsKDrAeELAdwLEJCfmwCsAAswkKHR4uLi4uAbMJCh0eLi4uLrBAGgGxECQRErEGGjk5ALEhABESsQMXOTkwMSUVJjU0NjMyFh8BHgEzMjY1NCYnNTIWFRQGIyImLwEuASMiBhUUHgUBHOqEWEVuEhoNPiwtP0AvV2xvU1ZhExkLSCUxUAkXEiURKlRUCdd3i1RUfj0rR05QVAJTf3VyfEtefDY0UFgeLR4UCwUFAAD//wAyAAADJAJ+ECcHrgFBANcQBgiaAAAAAQAyAAADJAHiACsAlgCyEgAAK7ArM7EfBOmwADKwGS+wCzOxGATpsCYyAbAsL7AV1rEcBemyHBUKK7NAHBgJK7AcELEIASuxKQXpsggpCiuzQAgrCSuxLQErsDYauj6981oAFSsKDrAiELAjwLEPE/mwDsAAsw4PIiMuLi4uAbMODyIjLi4uLrBAGgGxCBwRErESJjk5ALEZHxESsRUpOTkwMSU+BjU0JiMiBg8BDgEjIiY1NDYzFQ4BFRQWMzI2PwE+ATMyFhUUBwI6BCoRJRIXCVAxJUgLGRNhVlNvbFcvQD8tLD4NGhJuRViE6lQBBQULFB4tHlhQNDZ8Xkt8cnV/UwJUUE5HKz1+VFSLd9cJAAD//wAyAAADJAJ+ECYInAAAEAcHrgFBANf//wAyAAADtwLaECcIlwCrAAAQBgeuAAD//wAyAAADuALaECYIlwAAEAcHrgMSAAD//wAyAAADtwLaECcImACrAAAQBgeuAAD//wAyAAADuALaECYImAAAEAcHrgMSAAD//wAyAAADtwN2ECYHrgAAECcImACrAAAQBweuAoEBz///ADIAAAO4A3YQJweuAxIAABAmCJgAABAHB64B1gHP//8AMgAAA7QB4hAmB64AABAHCJoAkAAA//8AMgAAA7QB4hAnB64DDgAAEAYImgAA//8AMgAAA7QCfhAmB64AABAHCJsAkAAA//8AMgAAA7QCfhAnB64DDgAAEAYImwAA//8AMgAAA7QB4hAmB64AABAHCJwAkAAA//8AMgAAA7QB4hAnB64DDgAAEAYInAAA//8AMgAAA7QCfhAmB64AABAHCJ0AkAAA//8AMgAAA7QCfhAnB64DDgAAEAYInQAAAAEAMgFrAiACpgAqAKAAsBIvsCoztB8EAB8EK7AAMrAZL7ALM7QYBAAfBCuwJTIBsCsvsBXWtBwFABEEK7IcFQors0AcGAkrsBwQsQgBK7QoBQARBCuyCCgKK7NACCoJK7EsASuwNhq6PtHzvgAVKwoOsCEQsCLAsQ8Z+bAOwACzDg8hIi4uLi4Bsw4PISIuLi4usEAaAbEIHBESsRIlOTkAsRkfERKxFSg5OTAxATI+BTU0JiMiBg8BDgEjIiY1NDYzFQ4BFRQWMzI/AT4BMzIWFRQHAYYCHQsYDA8GNCAYMAcQDT84NkpHOR8qKR4/DxELSS06VpoBoQQDCA0THxM6NCMjUj0wUUpNUzYCNzQzL0RTNzdbT4oHAAAAAQAyAAAB0gLaAAcAKwCyBQAAK7IAAwArtAYCBQANK7EGBOkBsAgvsAXWsQQF6bABMrEJASsAMDEBMwMzESMRIQFrZ/n5VP60Atr+vf5pAUMAAAD//wAyAAAB0gN9ECYIrwAAEAYU0TIAAAAAAQAyAAAB0gLaAAcAKwCyBAAAK7IHAwArtAIFBAcNK7ECBOkBsAgvsATWsAcysQMF6bEJASsAMDETASERIxEzA5kBOf60VPn5Atr+af69AZcBQwD//wAyAAAB0gN2ECYIrwAAEAcHrgAAAc8AAQAyAAAB0gLaAAcAKwCyAAAAK7IDAwArtAYCAAMNK7EGBOkBsAgvsALWsQUF6bAHMrEJASsAMDEhASERMxEjEwFr/scBTFT5+QGXAUP+af69AAD//wAyAAAB4gN2ECcHrgE8Ac8QBgixAAD//wAyAAACSgN3ECcHrgGkAdAQJweuANQB0BAGCLEAAAABADIAAAHSAtoABwArALIBAAArsgQDACu0AwYBBA0rsQME6QGwCC+wA9awATKxBgXpsQkBKwAwMTMjEyMRMxEhmWf5+VQBTAFDAZf+vQAA//8AMgAAAeIDdhAnB64AAAHPEAYItBAA//8AMgAAAm0C2hAnCK0AmwAAEAYHrgAA//8AMgAAAm4C2hAmCK0AABAHB64ByAAA//8AMgAAAm0C2hAnCK8AmwAAEAYHrgAA//8AMgAAAm4C2hAmCK8AABAHB64ByAAA//8AMgAAAm0DdhAmB64AABAnCK8AmwAAEAcHrgCbAc///wAyAAACbgN2ECcHrgHIAAAQJgivAAAQBweuAAABz///ADIAAAJtAtoQJgeuAAAQBwixAJsAAP//ADIAAAJuAtoQJweuAcgAABAGCLEAAP//ADIAAAJ9A3YQJweuAdcBzxAGCLwAAP//ADIAAAJuA3YQJweuATwBzxAGCL0AAP//ADIAAAJtAtoQJgeuAAAQBwi0AJsAAP//ADIAAAJuAtoQJweuAcgAABAGCLQAAP//ADIAAAJtA3YQJweuAIsBzxAGCMAAAP//ADIAAAJ+A3YQJweuAAABzxAGCMEQAP//ADIAAAJtAtoQJgeuAKEQJgeuAGEQBwi0AJsAAAAAAAEAMgFtAUIC2gAHACgAsgQDACuwAy+0BgQAHwQrAbAIL7AD1rABMrQGBQARBCuxCQErADAxEyM3IzUzFTN6SJubO9UBbcilagAAAAABADIBbQHHAtoACQBEALIEAwArsAYzAbAKL7ELASuwNhq6wn/uTgAVKwqwBi4OsAfAsQkV+bAIwACyBwgJLi4uAbMGBwgJLi4uLrBAGgEAMDETJwcjExc3EyMn/VZANWxfYWk0PgFtw8MBberq/pPDAAAAAAEAMgFuAZ4C2gALAFIAsgADACuwCS+wBDO0CgQAHwQrsAIysgkKCiuzQAkHCSsBsAwvsAfWsAAytAYFABEEK7ABMrIGBwors0AGBAkrsgcGCiuzQAcJCSuxDQErADAxEzMVMxUjFSM1IzUzyjuZmTuYmALalTucnDsAAAABADIBbgGaAtYACwAAARcHFwcnByc3JzcXAXAqiooqiooqiooqigLWKoqKKoqKKoqKKooAAQAyAAADDAHIABEATACyDgAAK7EEBOmwCi+xBwTpsAAyAbASL7AQ1rQBBQAxBCuwARCxBgErtAsFADwEK7ILBgors0ALCQkrsRMBK7EGARESsQ0OOTkAMDETFRQWMjY9ASEVIRUUBiImPQGDRWhJAZP+v32keAHI0kVfYETSUpRigIBi5gAAAAEAMgAAAwwByAASAEoAsgUAACuxEATpsAovsQsE6bAAMgGwEy+wCNa0DQUAPAQrsggNCiuzQAgKCSuwDRCxEgErtAIFADEEK7EUASuxEg0RErAFOQAwMQEzFRQGIyImPQEhNSEVFBYyNjUCu1F6UFJ9/r8Bk0loRQHI5mKAgGKUUtJEYF9FAAABADL//gMMAcYAEQBMALIIAAArsAAzsQkE6bAEL7EOBOkBsBIvsArWtAcFADwEK7IKBwors0AKCAkrsAcQsQABK7QRBQAxBCuxEwErsQAHERKxDQ45OQAwMQU1NCYiBh0BITUhNTQ2MhYdAQK7RWhJ/m0BQX2keALSRV9gRNJSlGKAgGLmAAD//wAy//4DDAJrECcU0QC+/u4QBgjNAAAAAQAy//4DDAHHABMASgCyDAAAK7AAM7EJBOmwEC+xBQTpAbAUL7AB1rQABQAxBCuwABCxDAErtAkFADwEK7IJDAors0AJCwkrsRUBK7EMABESsAU5ADAxFyM1NDYzMhYdASEVITU0JiMiBhWDUXpQUn0BQf5tSTQ0RQLmYoCAYpRS0kRgX0UA//8AMv/+AwwCZBAmCM0AABAHB64AkAC9AAEAMgAAAfoC2gASAEgAsgsAACuyAQMAK7EABOm0CQwLAQ0rsQkE6QGwEy+wC9awADK0CgUAPAQrsAoQsRABK7QFBQA8BCuxFAErALEADBESsAU5MDETNTMyFhUUBisBESMRMzI2NCYjMuZigIBilFLSRGBfRQKJUXpQUn3+vwGTSWhF//8AMgAAAfoDdhAnB64AlwHPEAYIzwAAAAEAMgAAAfoC2gARAEoAshEAACuxAATpsggDACu0CgcRCA0rsQoE6QGwEi+wB9awADK0CgUAPAQrsAoQsQQBK7QOBQA8BCuxEwErALEHABESsQ0OOTkwMTczMjY0JisBETMRMzIWFAYrATLSRV9gRNJSlGKAgGLmUUVoSQGT/r99pHgAAAEAMgAAAfoC2gARAEoAsgkAACuyEAMAK7EBBOm0CwYJEA0rsQsE6QGwEi+wDta0BAUAPAQrsAQQsQkBK7QIBQA8BCuwADKxEwErALEBBhESsQ0OOTkwMQEjIgYUFjsBESMRIyImNDY7AQH60kVfYETSUpRigIBi5gKJRWhJ/m0BQX2keAAAAP//ADIAAAH6A3YQJweuAPABzxAGCNIAAAABADL//wH6AtoAEwBKALICAAArsRME6bIKAwArtAgNAgoNK7EIBOkBsBQvsAXWtBAFADwEK7AQELEJASu0DAUAPAQrsAAysRUBKwCxDRMRErEFEDk5MDElFSMiJjU0NjsBETMRIyIGFRQWMwH65mKAgGKUUtJEYF9FUVF6UFJ9AUH+bUk0NEX//wAyAAACgQN2ECcHrgF3Ac8QJgeuAAAQBwjSAIcAAP//ADIAAAKWA3YQJweuAPABzxAnB64B8AAAEAYI0gAAAAEAMgFtASUC2gARAFQAshADACu0AQQAHwQrsgYBACu0CwQAHwQrsgsGCiuzQAsJCSsBsBIvsA7WtAQFABEEK7AEELEJASu0CAUAEQQrsAAysRMBKwCxAQYRErENDjk5MDEBIyIGFBY7ARUjNSMiJjQ2OwEBJUYyQUAzRjoaSFdZRlQCoihGIqVsRnBLAAAAAAEAMgFtATgC2gAJAC8AsgMDACsBsAovsAfWsQACMjK0BgUACAQrsAQysQsBK7EGBxESsgEFCTk5OQAwMRM3JzUFBxcFNTcykpIBBp+f/vqSAiNMNjViVVdfNDQAAQAyAAACPgLaAAkAFgCyBwAAK7IDAwArAbAKL7ELASsAMDETLQE1DQM1JTIBMP7QAgz+pAFc/fQBMAFtnnRbwquwvVlxAAAAAgAyAAAC/wLaAA4AFgBiALIBAAArsgcDACuwADOxFgTptBIMAQcNK7ESBOkBsBcvsATWsRAF6bAQELEUASuxCQXpsRgBK7EUEBESsgcGDDk5ObAJEbEBDTk5ALEMARESsA05sRYSERKyCAkEOTk5MDEJAiY1NDYyFhQGKwEXAQQUFjI2NCYiAv/+XP71HmSMZGRGA4IBRv3lM0YzM0YC2v0mAc8zLkZkZIxk4gI2h0YzM0YzAAAA//8AMgAAAv8DfRAmCNwAABAHFNEBIAAAAAIAMgAAAv8C2gAOABYAYgCyCQAAK7AAM7ESBOmyDgMAK7QWAwkODSuxFgTpAbAXL7AL1rEQBemwEBCxFAErsQcF6bEYASuxFBARErIICQM5OTmwBxGxAg45OQCxFhIRErIHBgs5OTmxDgMRErACOTAxISMBBzMyFhQGIiY1NDcBAhQWMjY0JiIC/17+uoIDRmRkjGQeAQvVM0YzM0YCNuJkjGRkRjUsAc/980YzM0YzAAAA//8AMgAAAv8DdhAmCNwAABAHB64A8AHPAAIAMgAAAwYC2gAOABoAYACyAAAAK7ILAwArsQ8E6bQVBwALDSuxFQTpAbAbL7AJ1rAAMrESBemwEhCxGAErsQQF6bEcASuxGBIRErIHBgs5OTkAsQcAERKwATmwFRGxAg45ObAPErIICQM5OTkwMTM1AScVFAYiJjQ2MzIXASUiBhUUFjMyNjU0JjICMNxkjGRkRi8xAcr91iQyMiQjMzReAUyIAkZkZIxkHv7u3DMjJDIyJCI0AP//ADIAAAMGA04QJgjeAAAQBweuATABpwACADIAAAMGAtoADgAaAGAAsgAAACuyBAMAK7EPBOm0FQkABA0rsRUE6QGwGy+wC9axEgXpsBIQsRgBK7EHBemwADKxHAErsRgSERKyCAkEOTk5ALEJABESsA45sBURsQENOTmwDxKyBwYMOTk5MDEhCQE2MzIWFAYiJj0BBwEDIgYVFBYzMjY1NCYDBv0sAcoxL0ZkZIxk3AIwqiI0MyMkMjIBqgESHmSMZGRGAoj+tAIoNCIkMjIkIzMA//8AMgAAAwYDThAmCOAAABAHB64BMAGn//8AMgAAA6IDThAnB64BmgGnECcI4ACcAAAQBgeuAEP//wAyAAADmgNOECcHrgEwAacQJgjgAAAQBweuAvQAQwACADIBeQGfAtoADgAWAEcAsgUDACu0FgQAHwQrsAovtBIEAB8EKwGwFy+wFNa0CAUAEQQrsAAysRgBKwCxEgoRErIIAg45OTmwFhGwDTmwBRKwBzkwMQEVJTc2MzIWFAYjIiYnBzYUFjI2NCYiAZz+lugaFiMyMiMgLwVajxIaEhIaAbU8zoQPMkYyKh8ySxoSEhoSAAAAAAIAMgAAArQC2gAXAB8AdACyBAAAK7EUBOmyCgMAK7AAM7EfBOm0Gw4ECg0rsRsE6QGwIC+wBtaxEQXpsBgysBEQsR0BK7EMBemwDBCxFgErsQEF6bEhASuxHRERErQJCgQOEyQXObEWDBESsQMUOTkAsRsOERKwEDmwHxGxDAs5OTAxAREUBiImNRE0NjIWFAYjIicVFBYyNjURBBQWMjY0JiICtMX4xWSMZGRGLSmVsJX+JjNGMzNGAtr+SnaurnYBDEZkZIxkF3lTfX1TAbaHRjMzRjMAAAIAMgAAArQC2gAXAB8AdACyFQAAK7EFBOmyDwMAK7AAM7EbBOm0HwoVDw0rsR8E6QGwIC+wF9axAgXpsAIQsQ0BK7EdBemwHRCxBwErsBgysRIF6bEhASuxDQIRErEEFTk5sQcdERK0BQoODxQkFzkAsR8KERKwCDmwGxGxDQw5OTAxEzMRFBYyNj0BBiMiJjQ2MhYVERQGIiY1JDQmIgYUFjIyVJWwlSktRmRkjGTF+MUCLjNGMzNGAtr+SlN9fVN5F2SMZGRG/vR2rq526UYzM0YzAAAAAAIAMgAAArQC2gAXAB8AdACyDwAAK7AAM7EbBOmyFQMAK7EFBOm0HwoPFQ0rsR8E6QGwIC+wEtaxCAXpsBgysAgQsR0BK7ENBemwDRCxAQErsQAF6bEhASuxHQgRErQFCg4PFCQXObEBDRESsQQVOTkAsR8bERKxDQw5ObAKEbAIOTAxISMRNCYiBh0BNjMyFhQGIiY1ETQ2MhYVBBQWMjY0JiICtFSVsJUpLUZkZIxkxfjF/dIzRjMzRgG2U319U3kXZIxkZEYBDHaurnbpRjMzRjMAAgAyAAACtALaABcAHwB0ALIKAAArsAAzsR8E6bIEAwArsRQE6bQbDgoEDSuxGwTpAbAgL7AA1rEXBemwFxCxDAErsR0F6bAdELEQASuwGDKxBgXpsSEBK7EMFxESsQMUOTmxEB0RErQJCgQOEyQXOQCxGx8RErEMCzk5sA4RsBA5MDEzETQ2MhYVERQGIiY0NjMyFzU0JiIGFREkNCYiBhQWMjLF+MVkjGRkRi0plbCVAdozRjMzRgG2dq6udv70RmRkjGQXeVN9fVP+SodGMzNGM///ADIAAAK0A3YQJweuAQcBzxAGCOcAAP//ADIAAAK0A3YQJweuAQcBzxAGCOgAAAACADIAAAK0AtoAFwAfAHcAsgAAACuxAQTpshIDACuxCATpsBgytB0NABINK7EdBOkBsCAvsA/WsAAysRsF6bAbELEfASuxCgXpsAoQsQUBK7EVBemxIQErsR8bERKxDQw5ObAKEbAIOQCxDQERErEEFTk5sB0RsAU5sAgSswoODxQkFzkwMTM1ITI2NCYrARYVFAYiJjQ2OwEyFhAGIwIiBhQWMjY0MgFeU319UyEXZIxkZEa0eaureZFGMzNGM1Sw0rApLUZkZIxk1P7O1AKGM0YzM0YAAP//ADIAAAK0A3YQJgjrAAAQBweuAQcBzwACADIAAAK0AtoAFwAfAHcAsgEAACuxFgTpsgYDACuxEQTpsBgytB0MAQYNK7EdBOkBsCAvsATWsRQF6bAUELEOASuxGwXpsBsQsR8BK7EKBemwADKxIQErsRsOERKwEDmwHxGxDAs5OQCxDBYRErEDFDk5sB0RsBM5sBESswkKBA4kFzkwMSkBIiYQNjsBMhYUBiImNTQ3IyIGFBYzIQIiBhQWMjY0ArT+onmrq3m0RmRkjGQXIVN9fVMBXodGMzNGM9QBMtRkjGRkRi0psNKwAjIzRjMzRv//ADIAAAK0A3YQJgjtAAAQBweuATkBz///ADIAAANQA3YQJweuAaMBzxAnCO0AnAAAEAYHrgAA//8AMgAAAx4DdhAnB64BBwHPECYI7QAAEAcHrgJ4AAAAAgAyAW0BaALaAAcAHwCIALIWAwArtAgEAB8EK7AGMrAQL7QNBAAfBCuwHC+0AwQAHwQrAbAgL7AT1rQLBQARBCuwCxCxHgErtAEFABEEK7ABELEFASu0GgUAEQQrsA4ysSEBK7EBHhESsQgcOTmxGgURErAbOQCxHA0RErELEzk5sAMRsQoaOTmwCBKwHjmwFhGwGTkwMRIUFjI2NCYiIyIGFBY7ARUjIiY1NDY7ATIWFAYiJjU09BIaEhIaQikzMymkpDxWVT1PIzIyRjICkhoSEhoSS2pMNmpNTGoyRjIyIxD//wAyAAACtALaECYH0wAAEAcH0QEk/////wAyAAACtALaECYH1QAAEAcH0QEl/lL//wAyAAACtgLaECYH1wAAEAYU0gAAAAD//wAyAAACtgLaECcU0gFYAAAQBgfcAAAAAgAyAW0DBwLaABEAIwBCALISAwArsAAzAbAkL7Ac1rASMrQbBQARBCuwEzKwGxCxCgErsAAytAkFABEEK7ABMrElASuxChsRErENFjk5ADAxATMVNxcHFwcnFSM1Byc3JzcXJTMVNxcHFwcnFSM1Byc3JzcXAkA2dht2dht2NnYbdnYbdv6DNnYbdnYbdjZ2G3Z2G3YC2ohEL0NEL0SIiEQvREMvRIiIRC9DRC9EiIhEL0RDL0QAAAIAMgAAArQC2gAPAB8AbACyBAAAK7EMBOmyBwMAK7IAEBgzMzO0HRUEBw0rtB0EACsEKwGwIC+wBtaxCQXpsAkQsRcBK7QaBQAbBCuwGhCxHwErtBIFABsEK7ASELEOASuxAQXpsSEBK7EfGhEStQMEDAsUFSQXOQAwMQERFAYiJjURMxEUFjI2NREHMxUUBiImPQEzFRQWMjY1ArTF+MVUlbCVaUZ1qnZGT2xOAtr+SnaurnYBtv5KU319UwG2AdJFYWFF09MsNTUsAAIAMgAAArQC2gAPAB8AbACyEAAAK7IACBczMzOyFAMAK7EcBOm0DQUQFA0rtA0EACsEKwGwIC+wENaxHwXpsB8QsQEBK7QABQAbBCuwABCxCQErtAgFABsEK7AIELEYASuxFwXpsSEBK7EJABEStQQFExQbHCQXOQAwMTcjNTQ2MhYdASM1NCYiBhUHETQ2MhYVESMRNCYiBhUR70Z1qnZGT2xOvcX4xVSVsJUB0kVhYUXT0yw1NSzTAbZ2rq52/koBtlN9fVP+SgAAAAIAMgAAArYC2gAPAB8AaACyFwAAK7EYBOmyEAMAK7EfBOm0CAkXEA0rtAgEADcEK7QBABcQDSu0AQQANwQrAbAgL7AN1rQFBQAbBCuwBRCxHAErsRQF6bEhASsAsQkIERKwFDmwABGzBAUbHCQXObABErATOTAxEzUzMhYUBisBNTMyNjQmIychMhYQBiMhNSEyNjQmIyEz0kVhYUXT0yw1NSzTAUGFvr6F/r8BQWKLi2L+vwHxRnWqdkZPbE7p1v7S1lSl6KUAAgAyAAACtgLaAA8AHwBoALIBAAArsQ4E6bIGAwArsQkE6bQSHwEGDSu0EgQANwQrtBcaAQYNK7QXBAA3BCsBsCAvsATWsQwF6bAMELEVASu0HQUAGwQrsSEBKwCxHxIRErADObAaEbMMCxQVJBc5sBcSsAQ5MDEpASImEDYzIRUhIgYUFjMhJxUjIiY0NjsBFSMiBhQWMwK2/r+Fvr6FAUH+v2KLi2IBQQHSRWFhRdPTLDU1LNYBLtZUpeillUZ1qnZGT2xOAAABADIAAALuAtoAGQBZALIOAAArsgcDACuxEgTptAEYDgcNK7EBBOkBsBovsATWtBUFADwEK7AVELEOASu0CwUAPAQrsRsBK7EOFRESsQcAOTkAsQEOERKxCww5ObESGBESsAQ5MDEBIyImNTQ2MzIWFRE3MwERNCYjIgYVFBY7AQGUgGKAkWVilFx0/t5eRkVfYERsAUF/UlB4k1P+0l3+3QHgOm5CNDVKAAAAAQAyAAAC7gLaABkAWQCyDAAAK7ITAwArsQgE6bQAAQwTDSuxAATpAbAaL7AP1rQMBQA8BCuwDBCxBQErtBYFADwEK7EbASuxBQwRErEAEzk5ALEADBESsQ0POTmxCAERErAWOTAxATUzMjY1NCYjIgYVEQEzFxE0NjMyFhUUBiMBjGxEYF9FRl7+3nRclGJlkYBiAUFSSjU0Qm46/iABI10BLlOTeFBSfwAA//8AMgAAAu4DdhAmCPwAABAHB64BjAHPAAEAMgAAAu4C2gAZAFkAshMAACuxCATpsgwDACu0GQITDA0rsRkE6QGwGi+wFta0BQUAPAQrsAUQsQsBK7QQBQA8BCuxGwErsQsFERKxABM5OQCxAggRErAWObEMGRESsQ0POTkwMQEVIyIGFRQWMzI2NREBIycRFAYjIiY1NDYzAZRsRGBfRUZeASJ0XJRiZZGAYgGZUko1NEJuOgHg/t1d/tJTk3hQUn8AAP//ADIAAALuA3YQJgj+AAAQBweuAYkBzwABADIAAALuAtoAGQBZALIHAAArsRIE6bIOAwArtAAZBw4NK7EABOkBsBovsArWtA8FADwEK7APELEVASu0BAUAPAQrsRsBK7EVDxESsQcAOTkAsRkSERKwBDmxDgARErELDDk5MDEBMzIWFRQGIyImNREHIwERFBYzMjY1NCYrAQGMgGKAkWVilFx0ASJeRkVfYERsAZl/UlB4k1MBLl0BI/4gOm5CNDVKAAD//wAyAAAC7gN2ECYJAAAAEAcHrgC/Ac8AAQAyAW0BuwLaABcAaACyFwMAK7IJAQArtAoEAB8EK7AQL7QDBAAfBCsBsBgvsBPWtAAFABEEK7AAELEGASu0DQUAEQQrsgYNCiuzQAYJCSuxGQErsQYAERKwEDkAsQkDERKwDTmwChGxFRY5ObAXErAUOTAxExQWMzI2NCYrATUzMhUUBiMiJj0BByM37iUgIy8vIysriFA4M0g6TLwB5BwlIDQgNnA2OjcojTy9AAABADIAAAIeAtoACwBFALIHAAArsAIzsggDACuwADO0BQoHCA0rsQUE6QGwDC+wB9a0BgUAPAQrsAkysAYQsQMBK7AAMrQCBQA8BCuxDQErADAxATMRIxEhESMRMxEhAcxSUv64UlIBSALa/SYBRP68Atr+vAAAAP//ADIBbgGaAtYQBgjIAAD//wAyAAADOQN9ECYI1wAAEAcH8wEbAAD//wAyAAADOQLaECYI1wAAEAcH9AEbAAD//wAyAAADOQN2ECcH9AEbAAAQJweuAdcBzxAGCNcAAP//ADIAAALXAtoQJgjXAAAQBwf2ALkAAP//ADIAAALpA3YQJweuAkMBzxAmCNcAABAHB/YAuAAA//8AMgAAAzkC2hAmCNcAABAHB/kBGwAA//8AMgAAAzkDdhAnB64BCwHPECYI1wAAEAcH+QEbAAD//wAyAWwCUgLaECYI1wAAEAcICgEbAAAAAQAyAAACHgLaABgAWACyAgAAK7ANM7IJAwArsRIE6bQDGAIJDSuxAwTpAbAZL7AG1rACMrQVBQA8BCuwFRCxDgErtA0FADwEK7EaASuxDhURErMBAAkDJBc5ALESGBESsAY5MDEJASMTIiY1NDYzMhYVESMRNCYjIgYVFBYzAbH+5WThYn+RZWKUUl5GRV9gRAGT/m0BQX9SUHiTU/4MAeA6bkI0NUoAAQAyAAACHgLaABgAWACyDAAAK7AXM7IQAwArsQcE6bQWAQwQDSuxFgTpAbAZL7AM1rQLBQA8BCuwCxCxBAErtBMFADwEK7AXMrEaASuxBAsRErMAEBYYJBc5ALEHARESsBM5MDETMzI2NTQmIyIGFREjETQ2MzIWFRQGIxMjn4lEYF9FRl5SlGJlkX9i4WQBk0o1NEJuOv4gAfRTk3hQUn/+vwABADIAAAIeAtoAGABYALIQAAArsQcE6bIXAwArsAsztBYBEBcNK7EWBOkBsBkvsBPWsBcytAQFADwEK7AEELEKASu0DQUAPAQrsRoBK7EKBBESswAQFhgkFzkAsQEHERKwEzkwMQEjIgYVFBYzMjY1ETMRFAYjIiY1NDYzAzMBsYlEYF9FRl5SlGJlkX9i4WQBR0o1NEJuOgHg/gxTk3hQUn8BQQAAAAABADIAAAIeAtoAGABYALIJAAArsRIE6bINAwArsAEztAMYCQ0NK7EDBOkBsBkvsAzWtA8FADwEK7APELEVASu0BgUAPAQrsAIysRoBK7EVDxESswEACQMkFzkAsRgSERKwBjkwMRMBMwMyFhUUBiMiJjURMxEUFjMyNjU0JiOfARtk4WJ/kWVilFJeRkVfYEQBRwGT/r9/UlB4k1MB9P4gOm5CNDVKAAABADIAAALcAtoAGABmALIPAAArsgMDACuxEwTpshMDCiuzQBMYCSu0CwkPAw0rsQsE6QGwGS+wGNa0FwUAPAQrsBcQsQ8BK7QOBQA8BCuwBjKyDg8KK7NADgsJK7EaASuxDxcRErADOQCxCQsRErAHOTAxEzQ2MzIWFRE2OwEVIgYVIxE0JiMiBh0BIzKRZWKUSlgcUW1SXkZFX1ICElB4k1P+0UpSgjsB4DpuQjQyAAEAMgAAAtwC2gAZAGYAsgwAACuyFwMAK7EGBOmyBhcKK7NABgEJK7QPEAwXDSuxDwTpAbAaL7AM1rATMrQLBQA8BCuyDAsKK7NADA8JK7ALELECASu0AQUAPAQrsRsBK7ECCxESsBc5ALEQDxESsBM5MDEBFSM1NCYjIgYVERUjNCYjNTMyFxE0NjMyFgLcUl9FRl5SbVEcWEqUYmWRAhIyMjRCbjr+PBw7glJKAS9Tk3gAAAEAMgAAAtwC2gAZAGYAshcAACuxBgTpsgYXCiuzQAYBCSuyCwMAK7QPERcLDSuxDwTpAbAaL7AA1rQDBQA8BCuwAxCxCQErtBQFADwEK7AMMrIUCQors0AUDwkrsRsBK7EJAxESsBc5ALEPERESsBM5MDE3NTMVFBYzMjY1ETUzFBYzFSMiJxEUBiMiJjJSX0VGXlJtURxYSpRiZZHIMjI0Qm46AcQcO4JSSv7RU5N4AAAAAAEAMgAAAtwC2gAYAGYAsgMAACuxEwTpshMDCiuzQBMYCSuyDgMAK7QLCgMODSuxCwTpAbAZL7AG1rAOMrQQBQA8BCuyBhAKK7NABgsJK7AQELEWASu0AAUAPAQrsRoBK7EWEBESsAM5ALELChESsAc5MDElFAYjIiY1EQYrATUyNjUzERQWMzI2PQEzAtyRZWKUSlgcUW1SXkZFX1LIUHiTUwEvSlKCO/4gOm5CNDL//wAyAAAD7gN9ECcIEgHQAAAQJgkcAAAQBxTRAqYAAP//ADIAAAPuAtoQJwgSAdAAABAGCRwAAP//ADIAAAPuA3YQJwgSAdAAABAnB64CjAHPEAYJHAAA//8AMgAAAn0C2hAmCRwAABAGCBRfAAAA//8AMgAAAo8DdhAnB64B6QHPECYJHAAAEAYIFF8AAAD//wAyAAAD7gLaECYJHAAAEAcIFwHQAAD//wAyAAAD7gN2ECcHrgHAAc8QJgkcAAAQBwgXAdAAAAACADIBbQHaAtoABwAkAI4AsiADACu0BwQAEwQrsBcvtA0EABMEK7INFwors0ANEQkrsBkvtAgEABMEK7ACMgGwJS+wHda0AQUAEQQrsAEQsQUBK7QjBQARBCuwIxCxGQErtAoFABEEK7AKELEPASu0EgUAEQQrsSYBK7EFARESsCA5sCMRsAg5sQ8KERKwFzkAsQcIERKxHSM5OTAxEhQWMjY0JiIXMxUUFjI2PQEzFRQOAiMiNSMiJjU0NjMyFhUUZiAuICAuc1cPOA41BhEpH2B+LT4+LSw/AoYuICAuIG4xOSwrOh0dHSw0HZY/LSw/PywfAAAAAAMAMgFtAtwC2gAnAC8ANwDLALIYAwArsCMztDcEABMEK7AuMrAPL7QFBAATBCuyBQ8KK7NABQkJK7ASL7QdBAATBCuyACoyMjIyAbA4L7AV1rQxBQARBCuwMRCxNQErtBsFABEEK7AbELEgASu0KQUAEQQrsCkQsS0BK7QmBQARBCuwJhCxEQErtAIFABEEK7ACELEHASu0CgUAEQQrsTkBK7E1MRESsBg5sBsRsB05sSkgERKwHjmwLRGwIzmwJhKwADmxBwIRErAPOQCxNx0RErMVGyAmJBc5MDEBMxUUFjI2PQEzFRQOAiMiNSEiJjU0NjMyFhUUBzMmNTQ2MzIWFRQmFBYyNjQmIgQUFjI2NCYiAftXDzgONQYRKR9g/oAtPj4tLD8PSg8+LSw/oiAuICAu/t4gLiAgLgI4MTksKzodHR0sNB2WPy0sPz8sHxgYHyw/PywfNi4gIC4gIC4gIC4gAAAAAAEAMgAAAlQC2gAnAIMAsicAACuyIgMAK7EDBOm0HAknIg0rsRwE6bQUDiciDSuxFATpsg4UCiuzQA4SCSsBsCgvsB/WsQYF6bAGELESASuxEQXpsBEQsQsBK7EXBemwFxCxJwErsSYF6bEpASuxERIRErEJHDk5sAsRsgMUIjk5OQCxDgkRErIGFx85OTkwMQE0JiMiBhUUFjMyNTQmIyIGFSM0MzIWFRQOAiMiJjU0NjMyFhURIwIAb05Sazw1bxkOEQ5UczJJFStMMVZ1nnNwoVQBzE5vVEtMS3kSHBwmk1MsJEQ9JYNlbYOfb/40AAEAMgAAAlQC2gAnAIMAsgIAACuyBgMAK7ElBOm0DB8CBg0rsQwE6bQUGgIGDSuxFATpshoUCiuzQBoXCSsBsCgvsALWsQEF6bABELERASuxHQXpsB0QsRcBK7EWBemwFhCxIgErsQkF6bEpASuxFx0RErIUBiU5OTmwFhGxDB85OQCxGh8RErIJESI5OTkwMRMRIxE0NjMyFhUUBiMiLgI1NDYzMhUjNCYjIgYVFDMyNjU0JiMiBoZUoXBznnVWMUwrFUkyc1QOEQ4ZbzU8a1JObwHM/jQBzG+fg21lgyU9RCQsU5MmHBwSeUtMS1RvAAEAMgAAAlQC2gAnAIMAsgYAACuxJQTpsgEDACu0FBoGAQ0rsRQE6bIaFAors0AaFgkrtAwfBgENK7EMBOkBsCgvsAnWsSIF6bAiELEWASuxFwXpsBcQsR0BK7ERBemwERCxAAErsQMF6bEpASuxFxYRErEMHzk5sB0RshQGJTk5OQCxHxoRErIJESI5OTkwMQERMxEUBiMiJjU0NjMyHgIVFAYjIjUzFBYzMjY1NCMiBhUUFjMyNgIAVKFwc551VjFMKxVJMnNUDhEOGW81PGtSTm8BDgHM/jRvn4NtZYMlPUQkLFOTJhwcEnlLTEtUbwAAAAABADIAAAJUAtoAJwCDALIiAAArsQME6bImAwArtBQOIiYNK7EUBOmyDhQKK7NADhEJK7QcCSImDSuxHATpAbAoL7Al1rEABemwABCxFwErsQsF6bALELERASuxEgXpsBIQsQYBK7EfBemxKQErsRELERKyAxQiOTk5sBIRsQkcOTkAsQkOERKyBhcfOTk5MDETFBYzMjY1NCYjIhUUFjMyNjUzFCMiJjU0PgIzMhYVFAYjIiY1ETOGb05Sazw1bxkOEQ5UczJJFStMMVZ1nnNwoVQBDk5vVEtMS3kSHBwmk1MsJEQ9JYNlbYOfbwHMAAACADIAAAKWAmYAAwAbAGQAshgAACuxCQTpsgEBACuxAgTptBEQGAINK7ERBOkBsBwvsBvWtAYFADwEK7AGELEMASu0FQUAPAQrsAAysgwVCiuzQAwBCSuwEDKxHQErsQwGERKwGDkAsRAJERKxBBU5OTAxASE1IQEzFRQWMzI2NTQmIyE1ITIWFRQGIyImNQKW/ZwCZP5nUko1NEJuOv6WAX5Tk3hQUn8CFFL+/GxEYF9FRl5SlGJlkYBiAAIAMgAAApYCZgADABsAZACyCAAAK7EXBOmyAAEAK7EBBOm0DhEIAQ0rsQ4E6QGwHC+wC9awADK0FAUAPAQrshQLCiuzQBQDCSuwDzKwFBCxGgErtAUFADwEK7EdASuxGhQRErAIOQCxERcRErELBDk5MDETNSEVBxUUBiMiJjU0NjMhFSEiBhUUFjMyNj0BMgJky39SUHiTUwF+/pY6bkI0NUoCFFJSsoBigJFlYpRSXkZFX2BEbAACADIAAAKWAmYAAwAbAGQAsg8AACuxEATpsgABACuxAQTptAgXDwENK7EIBOkBsBwvsATWtBsFADwEK7AbELEUASu0CwUAPAQrsAIyshQLCiuzQBQACSuwDzKxHQErsRQbERKwCDkAsRcQERKxCwQ5OTAxEzUhFQE1NDYzMhYVFAYjITUhMjY1NCYjIgYdATICZP5nf1JQeJNT/oIBajpuQjQ1SgIUUlL+doBigJFlYpRSXkZFX2BEbAAAAAIAMgAAApYCZgADABsAZACyEgAAK7EPBOmyAAEAK7EBBOm0GAkSAQ0rsRgE6QGwHC+wFdawADK0DAUAPAQrsgwVCiuzQAwDCSuwEDKwDBCxBQErtAQFADwEK7EdASuxBQwRErAYOQCxCQ8RErEEFTk5MDETNSEVAyM1NCYjIgYVFBYzIRUhIiY1NDYzMhYVMgJky1JKNTRCbjoBav6CU5N4UFJ/AhRSUv52bERgX0VGXlKUYmWRgGIAAAAAAgAyAW0BoALaAAMAGQBwALICAwArtAEEAB8EK7ARL7QOBAAfBCuwCS+0FwQAHwQrsgkXCiuzQAkFCSsBsBovsBTWsAEytAsFABEEK7ILFAors0ALAAkrsA8ysAsQsQUBK7QEBQARBCuxGwErsQULERKwFzkAsQkOERKwFDkwMQEhNSEDIzU0JiIGFRQWOwEVISImNTQ2MzIVAaD+kgFujjgeNB4jHPf+8Sg3OjZwAqI4/uMrIy8vIyAjOEgzOFKKAAAAAAEAMgAAAtIC2gATAEIAsg0AACuxCgTpsgIDACu0EwQNAg0rsRME6QGwFC+wENa0BwUAPAQrsgcQCiuzQAcMCSuxFQErALEEChESsBA5MDEBJzUBISIGFRQWOwEVIyImNTQ2MwIMfAFC/lo6bkI0MjJQeJNTAex6dP7AXkZFX1KRZWKU//8AMgAAAtIC2hAmCScAABAHB64AuAEzAAEAMgAAAtIC2gATAEIAsgIAACuyDAMAK7ELBOm0AAMCDA0rsQAE6QGwFC+wB9a0EAUAPAQrsgcQCiuzQAcMCSuxFQErALELAxESsBA5MDE3FxUBITI2NTQmKwE1MzIWFRQGI/h8/r4BpjpuQjQyMlB4k1PuenQBQF5GRV9SkWVilAAA//8AMgAAAtIC7BAnB64BCQFFEAYJKQAAAAEAMgAAAtIC2gATAEIAshIAACuyBwMAK7EKBOm0ARASBw0rsQEE6QGwFC+wBNa0DQUAPAQrsg0ECiuzQA0ICSuxFQErALEKEBESsAQ5MDElIyImNTQ2OwEVIyIGFRQWMyEBNQIM9FOTeFAyMjRCbjoBpv6+7pRiZZFSX0VGXv7AdAAA//8AMgAAAtIC6xAmCSsAABAHB64BKAFEAAEAMgFtAaAC2gAPAD8AsgcDACu0CAQAHwQrsAEvtAwEAB8EKwGwEC+wBNa0CgUAEQQrsgoECiuzQAoHCSuxEQErALEIDBESsAQ5MDEBIyImNTQ2MxUiFRQ7AQc1AR2MKTY5NzpB978B8z4yNUI2QTq8TAAAAQAyAAACTALaAA8AVwCyCQAAK7IAAwArtAsMCQANK7AEM7ELBOmwBjK0DgIJAA0rsQ4E6QGwEC+wCdawDTKxCAXpsQEDMjKyCAkKK7NACAYJK7IJCAors0AJCwkrsREBKwAwMQEzAzMVMxUjFSM1IzUzNSEBa2f5+Xp6VHh4/rQC2v69y1R4eFR3AAABADIAAAJMAtoADwBXALIIAAArsg8DACu0CgsIDw0rsAMzsQoE6bAFMrQCDQgPDSuxAgTpAbAQL7AI1rEMDzIysQcF6bACMrIHCAors0AHBQkrsggHCiuzQAgKCSuxEQErADAxCQEhFTMVIxUjNSM1MzUzAwETATn+tHh4VHp6+fkC2v5pd1R4eFTLAUMAAP//ADIAAAJMA3YQJgkvAAAQBweuAHoBzwABADIAAAJMAtoADwBVALIAAAArsgcDACuyBAEAK7ALM7EFBOmwCTK0Ag4ABQ0rsQIE6QGwEC+wAtawBjKxDQXpsQgPMjKyDQIKK7NADQsJK7ICDQors0ACBAkrsREBKwAwMSEBITUjNTM1MxUzFSMVIxMBa/7HAUx4eFR6evn5AZd3VHh4VMv+vQAA//8AMgAAAkwDdhAnB64BPAHPEAYJMQAAAAEAMgAAAkwC2gAPAFUAsgEAACuyCAMAK7IFAQArsAwzsQYE6bAKMrQOAwEGDSuxDgTpAbAQL7AD1rEBBzIysQ4F6bAJMrIOAwors0AODAkrsgMOCiuzQAMFCSuxEQErADAxISMTIzUjNTM1MxUzFSMVIQETZ/n5enpUeHgBTAFDy1R4eFR3AP//ADIAAAJMA3YQJweuAGoBzxAGCTMAAAABADIBbQFSAtoADwBRALIIAwArsAIvtA4EAB8EK7AFL7AMM7QGBAAfBCuwCjIBsBAvsATWsAcytA4FABEEK7AJMrIOBAors0AODAkrsgQOCiuzQAQFCSuxEQErADAxEyM3IzUjNTM1MxUzFSMVM7hIcGtDQzZERKcBbZFpNj09NjMAAAACADIAAAG2AtoADQAVAF8AsgkAACuwDDOxEQTpsgADACu0FQQJAA0rsRUE6QGwFi+wDdaxDAXpsQEOMjKwDBCxEwErsQcF6bEXASuxEwwRErEECTk5ALERCRESsAs5sBURsQcGOTmwBBKwAjkwMRMzETYzMhYUBiMiJxUjNhQWMjY0JiIyVDE9UHJyUD0xVFRAXEBAXALa/osjc6JzIyPyXEBAXEAAAAABADIAAAHRAtoADgA/ALIHAAArsgwDACuwCDO0AwQABwQrAbAPL7AH1rEGBemwCTKyBgcKK7NABgAJK7EQASsAsQwDERKxBQo5OTAxARQGIyInESMRMxU2MzIWAdF0TVA6VFQ4TlNyAhRTbjj+dQLaNzZ2AAEAMgAAAdEC2gAOAD0AsgYDACuwDC+wCDO0AwQABwQrAbAPL7AJ1rAFMrEIBemyCQgKK7NACQAJK7EQASsAsQMMERKxBQo5OTAxNzQ2MzIXETMRIzUGIyImMnRNUDpUVDdPU3LGU244AYv9Jjc2dgABADIAAAHRAtoADgA9ALIIAwArsAMvsAYztAwEAAcEKwGwDy+wB9axBgXpsAkysgYHCiuzQAYACSuxEAErALEMAxESsQUKOTkwMSUUBiMiJxUjETMRNjMyFgHRclNOOFRUOlBNdMZPdjY3Atr+dThuAAAAAAEAMgAAAdEC2gAOAD8AsgkAACuyAwMAK7AGM7QMBAAHBCsBsA8vsAnWsAUysQgF6bIJCAors0AJAAkrsRABKwCxAwwRErEFCjk5MDETNDYzMhc1MxEjEQYjIiYyclNPN1RUOlBNdAIUT3Y2N/0mAYs4bgAAAQAyAAACHgLaAAkAQACyCQAAK7IAAwArsQME6bQHBAkADSuxBwTpAbAKL7AJ1rQIBQA8BCuwAzKyCAkKK7NACAYJK7ABMrELASsAMDETIRUhFSEVIREjMgHs/mYBmv5mUgLaUvNS/r0AAAAAAQAyAAACHgLaAAkAQACyAQAAK7ECBOmyCAMAK7QGBQEIDSuxBgTpAbAKL7AD1rAHMrQABQA8BCuyAwAKK7NAAwEJK7AFMrELASsAMDEpATUhNSE1IREzAh7+FAGa/mYBmlJS81IBQwABADIAAAIeAtoACQBAALIAAAArsQcE6bIBAwArtAMGAAENK7EDBOkBsAovsADWtAcFADwEK7ACMrIHAAors0AHCQkrsAQysQsBKwAwMTMRMxEhFSEVIRUyUgGa/mYBmgLa/r1S81IAAAEAMgAAAh4C2gAJAEAAsgIAACuyCQMAK7EIBOm0BAUCCQ0rsQQE6QGwCi+wAtawBjK0AQUAPAQrsgIBCiuzQAIECSuwCDKxCwErADAxAREjESE1ITUhNQIeUv5mAZr+ZgLa/SYBQ1LzUgAAAAEAMgAAAewC2gAXAF4AshYAACuyFwMAK7ALM7EUBOm0BhAWFw0rsQYE6QGwGC+wFta0FQUAPAQrsBUQsRIBK7QBBQA8BCuwARCxCgErtA0FADwEK7EZASuxARIRErAQObENChESsA85ADAxARUUHgIyPgI9ATMVFAYiJj0BIxEjEQEkAgsYLBgLAlJIikhOUgLavR4bHAkJHBsevb1NY2NNa/14AtoAAAEAMgAAAewC2gAXAF4AsgAAACuwCzOxEwTpshUDACu0BhAAFQ0rsQYE6QGwGC+wDNa0CwUAPAQrsAsQsQABK7QTBQA8BCuwExCxFAErtBcFADwEK7EZASuxCwwRErAPObETABESsBA5ADAxMzU0LgIiDgIdASM1NDYyFh0BMxEzEfoCCxgsGAsCUkiKSE5SvR4bHAkJHBsevb1NY2NNawKI/SYAAQAyAAAB7ALaABcAXgCyAQAAK7AMM7EEBOmyAgMAK7QTCQECDSuxEwTpAbAYL7AB1rQEBQA8BCuwBBCxBQErtAAFADwEK7AAELENASu0DAUAPAQrsRkBK7EABRESsAg5sQwNERKwCTkAMDEhIxEzETM1NDYyFh0BIzU0LgIiDgIVASTyUk5IikhSAgsYLBgLAgLa/XhrTWNjTb29HhscCQkcGx4AAAAAAQAyAAAB7ALaABcAXgCyAwAAK7IAAwArsAwzsQUE6bQTCQMADSuxEwTpAbAYL7AL1rQOBQA8BCuwDhCxFwErtAYFADwEK7AGELEDASu0AgUAPAQrsRkBK7EOCxESsAk5sQYXERKwCDkAMDETMxEjESMVFAYiJj0BMxUUHgIyPgI1+vJSTkiKSFICCxgsGAsCAtr9JgKIa01jY029vR4bHAkJHBseAAAAAQAyAAAB/wLaAAkAKACyBQAAK7IGAwArsAAzAbAKL7AF1rEEBemxCwErALEGBRESsAg5MDEBCwEjESMRMxc3Af/RoQdUiXNzAtr+kwEY/XsC2snJAAAAAAEAMgAAAf8C2gAJACgAsgAAACuwBjOyBAMAKwGwCi+wA9axBgXpsQsBKwCxBAARErAIOTAxMxsBMxEzESMnBzLRoQdUiXNzAW3+6AKF/SbJyQAAAAEAMgAAAf8C2gAJACgAsgQAACuwADOyBQMAKwGwCi+wBNaxBwXpsQsBKwCxBQQRErACOTAxISMnByMRMxEzEwH/XnNziVQHocnJAtr9ewEYAAAAAAEAMgAAAf8C2gAJACgAsgYAACuyAAMAK7ADMwGwCi+wBtaxBQXpsQsBKwCxAAYRErACOTAxEzMXNzMRIxEjAzJec3OJVAehAtrJyf0mAoX+6AAAAAEAMgAAAkQC2gAUAGEAsgwAACuxCATpsgkDACu0AxIMCQ0rsQME6bISAwors0ASAAkrAbAVL7AA1rEUBemwFBCxDwErsQUF6bAFELEIASuxCwXpsRYBK7EPFBESsQMCOTkAsRIIERKxBQ85OTAxEzQ2MhYVFBYzETMRIyImNTQmIgYVMmeSZzEtVFRVXTZMNgEJSWdnSUZvAob9JphxJjY2JgAAAQAyAAACRALaABQAYQCyCQAAK7ENBOmyCwMAK7QTBAkLDSuxEwTpsgQTCiuzQAQACSsBsBUvsArWsQ0F6bANELEQASuxBgXpsAYQsQEBK7EABemxFgErsQEGERKxEhM5OQCxBA0RErEGEDk5MDEBIzQmIgYVFAYrAREzETI2NTQ2MhYCRFQ2TDZdVVRULTFnkmcBCSY2NiZxmALa/XpvRklnZwABADIAAAJEAtoAFABhALIMAAArsgkDACuxDQTptBMEDAkNK7ETBOmyBBMKK7NABAAJKwGwFS+wANaxAQXpsAEQsQYBK7EQBemwEBCxDAErsQsF6bEWASuxBgERErESEzk5ALENBBESsQYQOTkwMRMzFBYyNjU0NjsBESMRIgYVFAYiJjJUNkw2XVVUVC0xZ5JnAdEmNjYmcZj9JgKGb0ZJZ2cAAAEAMgAAAkQC2gAUAGEAsgoAACuyDAMAK7EIBOm0AxIKDA0rsQME6bISAwors0ASAAkrAbAVL7AK1rEJBemwCRCxBQErsQ8F6bAPELEUASuxAAXpsRYBK7EUDxESsQMCOTkAsQgSERKxBQ85OTAxARQGIiY1NCYjESMRMzIWFRQWMjY1AkRnkmcxLVRUVV02TDYB0UlnZ0lGb/16AtqYcSY2NiYAAgAyAAADewLaAAYACQAsALIEAAArsgUDACuwAjO0AAcEBQ0rsQAE6QGwCi+xCwErALEHBBESsAg5MDEBIRMzCQEzExc3ATMBSKJe/lz+W1/SdHQBwQEZ/SYC2v6TyckAAgAyAAADewLaAAYACQAsALIDAAArsAUzsgQDACu0AQkDBA0rsQEE6QGwCi+xCwErALEECRESsAg5MDEBIQMjCQEjAycHAnr+uKJeAaQBpV/SdHQBGf7nAtr9JgFtyckAAgAyAAACpALaAAYACQAYALIAAwArAbAKL7AE1rEIBemxCwErADAxEwkBNTcRJwUVNzICcv2O5+cBO5QC2v6T/pNaiQEUibuwWAAA//8AMgAAAqQC2hAnB9EAD/8pEAYJTQAA//8AMgAAAqQC2hAmB64AABAGCU0AAAAAAAIAMgAAAqQC2gAGAAkAGACyAAAAKwGwCi+wB9axBQXpsQsBKwAwMSEJARUHERclNQcCpP2OAnLn5/7FlAFtAW1aif7sibuwWAAAAAACADIAAAN7AtoABgAJACwAsgIAACuyAwMAK7AAM7QFCAIDDSuxBQTpAbAKL7ELASsAsQgCERKwCTkwMQEzCQEzFyEHIRMDHV7+XP5bXzkCGjD+Rt0C2v0mAtpjVP6BAAACADIAAAN7AtoABgAJACwAsgEAACuwAzOyAgMAK7QGBwECDSuxBgTpAbAKL7ELASsAsQIHERKwCTkwMTMjCQEjJyE3IQOQXgGkAaVfOf3mMAG63QLa/SZjVAF/AAIAMgAAAqQC2gAGAAkAGACyAQMAKwGwCi+wBdaxCAXpsQsBKwAwMRM1CQE1NxEXESUyAnL9jlBUASsCgFr+k/6TWjABxjH+nLIAAP//ADIAAAKkAtoQJglTAAAQBxTTAO4AAP//ADIAAAKkAtoQJweuAM0AABAGCVMAAAACADIAAAKkAtoABgAJABgAsgEAACsBsAovsAfWsQYF6bELASsAMDElFQkBFQcRJxEFAqT9jgJyUFT+1VpaAW0BbVow/joxAWSyAAAAAQAyAAADewLaAAgANwCyAQAAK7ICAwArsQAFMzMBsAkvsATWtAcFADwEK7EKASuxBwQRErABOQCxAgERErEEBzk5MDEJAjMBETMRAQN7/lz+W18BHVIBHQLa/SYC2v4RAe/+EQHvAAABADIAAAN7AtoACAA3ALIAAAArsQIFMzOyAQMAKwGwCS+wBta0BQUAPAQrsQoBK7EFBhESsAE5ALEBABESsQQHOTkwMTMJASMBESMRATIBpAGlX/7jUv7jAtr9JgHv/hEB7/4RAAAAAAEAMgAAAqQC2gAIACAAsgADACuwBS+xBgTpAbAJL7EKASsAsQYFERKwATkwMRMJATUlITUhJTICcv2OAYr+dgGK/nYC2v6T/pNa6lLqAAAAAQAyAAACpALaABAATACyDQMAK7AFL7AAM7EGBOmwCjKyBQYKK7NABQMJK7IGBQors0AGCAkrAbARL7AD1rAHMrQCBQARBCuwCTKxEgErALEGBRESsA45MDEBIRUjNSM1MzUzFSElNQkBNQG8/vk7SEg7AQf+dgJy/Y4BRG1tUm1t6lr+k/6TWgAAAAADADIAAAKkAtoABQANABgAaQCyFQMAK7AEL7AOM7EFBOmwEjKzDwQNDiu0CQQADwQrAbAZL7AE1rEUFzIysQIF6bICBAors0ACAwkrsAAysAIQsQcBK7QLBQAaBCuxGgErALEFBBEStAYHCgsWJBc5sRUJERKwFDkwMRMGFBcjNRY0NjIWFAYiNyM2NCczJTUJATWZDAxneiMuIyMu7YkMDIn+dgJy/Y4BlhIuElJCMisrMikZEi4S6lr+k/6TWgABADIAAAKkAtoACAAgALIAAAArsAcvsQQE6QGwCS+xCgErALEEBxESsAE5MDEhCQEVBSEVIQUCpP2OAnL+dgGK/nYBigFtAW1a6lLqAAAAAAMAMgAAA3sC2gAKAA0AEABOALIBAAArsgIDACuxAAYzM7QEDwECDSuwCzOxBATpsAgyAbARL7AQ1rAFMrQNBQA8BCuwBzKxEgErsQ0QERKwATkAsQ8BERKxDRA5OTAxCQIzEzMRMxEzEwMjFScjFwN7/lz+W1+ag1KDmspTUlNTAtr9JgLa/vQBDP70AQz+opGRkQADADIAAAN7AtoACgANABAATgCyAAAAK7ECBjMzsgEDACu0CQsAAQ0rsA4zsQkE6bAEMgGwES+wB9awDDK0BgUAPAQrsA4ysRIBK7EGBxESsAE5ALEBCxESsQ0QOTkwMTMJASMDIxEjESMDEzM1FzMnMgGkAaVfmoNSg5rKU1JTUwLa/SYBDP70AQz+9AFekZGRAAAAAwAyAAACpALaAAoADQAQADwAsgEDACuwBy+wDjOxCATpsAwyAbARL7AF1rAJMrQPBQA8BCuwCzKxEgErALEIBxESsAI5sAERsAs5MDETNQkBNTc1IzUzNRcVMwcVNzICcv2OqqqqUo6OjgKAWv6T/pNaZYVShTFUUlRUAAMAMgAAAqQC2gACAAUAGABqALITAwArsAovsQMGMzOxCwTpsQEPMjKyCgsKK7NACggJK7ILCgors0ALDQkrAbAZL7AI1rAMMrQHBQARBCuwDjKwBxCxFwErsBAytAQFADwEK7AAMrEaASsAsQsKERKwFDmwExGwADkwMQEVMwcVNyEVIzUjNTM1MxUzNSc1CQE1NzUBLo6Ojv7fOy4uO0GqAnL9jqoB6lRSVFRtbVJtbYVlWv6T/pNaZYUABQAyAAACpALaAAoADQAQABoAIACUALIGAwArsB8vsA4zsSAE6bAMMrMPHxkOK7QUBAAPBCsBsCEvsB/WsQUIMjK0HQUAEQQrsh0fCiuzQB0eCSuwGzKwHRCxEQErtBYFADAEK7AWELEKASuwAzK0DwUAPAQrsAsysSIBK7EPChESsAE5ALEfGRESsAA5sCARtAIBBxEWJBc5sBQSsAM5sAYRsQQLOTkwMRM2NCc1JzUJATU3ExU3BxU3JTQ2MhYVFAYiJicGFBcjNfALC74Ccv2OvlJ6enr+th4uHh4uHhMMDC0BQxQsFHhxWv6T/pNacQETSQFSSEgpGioqGhkpKUISLhJSAAAAAwAyAAACpALaAAoADQAQADwAsgEAACuwDS+wCDOxEATpsAYyAbARL7AL1rAOMrQKBQA8BCuwBTKxEgErALENARESsAs5sBARsAI5MDElFQkBFQcVMxUjFSc1Izc1BwKk/Y4CcqqqqlKOjo5aWgFtAW1aZYVShTFUUlRUAAIAMgAAAwwC2gAHAA8AOgCyDAAAK7EEBOmyDwMAK7EABOkBsBAvsA7WsQEF6bABELEGASuxCQXpsREBK7EGARESsQsMOTkAMDETERQWMjY1ETcRFAYgJjURhqXopVTW/tLWAob+vWKLi2IBQ1T+aYW+voUBlwAAAAIAMgAAAwwC2gAHAA8AOgCyCAAAK7EHBOmyDAMAK7EEBOkBsBAvsAjWsQcF6bAHELEAASuxDwXpsREBK7EABxESsQsMOTkAMDElETQmIgYVEQcRNDYgFhURAril6KVU1gEu1lQBQ2KLi2L+vVQBl4W+voX+aQAAAAIAMgAAAwwC2gAHAA8AOgCyDwAAK7EABOmyCAMAK7EHBOkBsBAvsA/WsQAF6bAAELEEASuxDAXpsREBKwCxBwARErELDDk5MDE3ITI2NCYjISchMhYQBiMhhgFDYouLYv69VAGXhb6+hf5pVKXopVTW/tLWAAAA//8AMgAAAwwC2hAnB9EA0v8pEAYJZQAA//8AMgAAAwwC2hAnB64BGAAAEAYJZQAAAAIAMgAAAwwC2gAHAA8AOgCyCQAAK7EGBOmyDgMAK7EBBOkBsBAvsAzWsQQF6bAEELEHASuxCAXpsREBKwCxAQYRErELDDk5MDEBISIGFBYzIRchIiYQNjMhArj+vWKLi2IBQ1T+aYW+voUBlwKGpeilVNYBLtYAAAIAMgAAAwwC2gAIABEARQCyBgAAK7EOBOmyAAMAK7ACMwGwEi+wCNaxCwXpsAsQsRABK7EDBemxEwErsRALERKyBQYBOTk5ALEADhESsQEKOTkwMRMFJREUBiAmNS0BERQWMjY1ETIBbQFt1v7S1gFt/uel6KUC2tPT/mmFvr6FY6L++2KLi2IBBQAAAgAyAAADDALaAAgAEQBFALICAAArsAAzsgYDACuxDgTpAbASL7AC1rERBemwERCxCgErsQAF6bETASuxChERErIFBgE5OTkAsQ4CERKxAQo5OTAxISUFETQ2IBYVDQERNCYiBhURAwz+k/6T1gEu1v6TARml6KXT0wGXhb6+hWOiAQVii4ti/vsAAAACADIAAAMMAtoACAARADEAsgAAACuxCgTpsgIDACuxEQTpAbASL7AO1rEGBemxEwErALERChESsgUGATk5OTAxMxMDITIWEAYjCwEhMjY0JiMhMtPTAZeFvr6FY6IBBWKLi2L++wFtAW3W/tLWAW3+56XopQAAAP//ADIAAAMMAtoQJwfRAZr/KRAGCWsAAP//ADIAAAMMAtoQJweuAaoAABAGCWsAAAACADIAAAMMAtoACAARADEAsgMAACuxEATpsggDACuxCwTpAbASL7AG1rEOBemxEwErALELEBESsgUGATk5OTAxAQMTISImEDYzGwEhIgYUFjMhAwzT0/5phb6+hWOi/vtii4tiAQUC2v6T/pPWAS7W/pMBGaXopQACADIAAAMMAtoABwATAEoAsgwAACuxBATpsg8DACuwCDO0EQAMDw0rsREE6QGwFC+wDtaxAQXpsBAysAEQsQYBK7ASMrEJBemxFQErsQYBERKxCww5OQAwMRMVFBYyNj0BExEUBiAmNREzFSE1hqXopVTW/tLWVAIyAdGOYouLYo4BCf5phb6+hQGXtbUAAAACADIAAAMMAtoABwATAEoAsggAACuwDzOyDAMAK7EEBOm0EgcIDA0rsRIE6QGwFC+wCNaxEwXpsAYysBMQsRABK7AAMrEPBemxFQErsRATERKxCww5OQAwMQE1NCYiBh0BAxE0NiAWFREjNSEVAril6KVU1gEu1lT9zgEJjmKLi2KO/vcBl4W+voX+abW1AAACADIAAAMMAtoABwATAEAAsg8AACuxEATpsAAysggDACuxEwTpsAYyAbAUL7AR1rEABemwABCxBAErsQwF6bEVASsAsRMQERKxCww5OTAxJTMyNjQmKwElITIWEAYjITUzESMBO45ii4tijv73AZeFvr6F/mm1tVSl6KVU1v7S1lQCMv//ADIAAAMMAtoQJwfRAWj/KRAGCXEAAP//ADIAAAMMAtoQJweuAXgAABAGCXEAAAACADIAAAMMAtoABwATAEAAsgkAACuxBgTpsBIysg4DACuxAQTpsBAyAbAUL7AM1rEEBemwBBCxBwErsRIF6bEVASsAsQEGERKxCww5OTAxASMiBhQWOwEFISImEDYzIRUjETMCA45ii4tijgEJ/mmFvr6FAZe1tQKGpeilVNYBLtZU/c4AAAAAAQAyAa4BXgLaAAcAPgCyAwMAK7AAL7QBBAAfBCuwBTIBsAgvsALWtAUFABEEK7IFAgors0AFBwkrsgIFCiuzQAIACSuxCQErADAxEzUzNTMVMxUyeTt4Aa478fE7AAAAAQAyAAACoALaAB4AXgCyBwAAK7ADM7EQBOmwGTKyCwMAK7EUHTMzAbAfL7AK1rENBemwDRCxEwErsRYF6bAWELEcASuxAAXpsSABK7ETDRESsAc5sBYRsAU5sBwSsAM5ALEQBxESsAU5MDElFAYjIicGIyImNREzERQWMzI2NREzERQWMzI2NREzAqBoSU83N09JaFQ3JiU3VDclJjdUskpoPj5oSgIo/dgmNjYmAij92CY2NiYCKAAAAAABADIAAAKgAtoAHgBeALIeAAArsQsUMzOyAwMAK7AHM7EZBOmwEDIBsB8vsB7WsR0F6bAdELEVASuxFAXpsBQQsQwBK7ELBemxIAErsRUdERKwAzmwFBGwBTmwDBKwBzkAsQMZERKwBTkwMRM0NjMyFzYzMhYVESMRNCYjIgYVESMRNCYjIgYVESMyaElPNzdPSWhUNyYlN1Q3JSY3VAIoSmg+PmhK/dgCKCY2Nib92AIoJjY2Jv3YAAAAAAEAMgAAAqAC2gAgAFIAsg0AACuxDgTpsiADACuxHwTptBYXDSANK7EWBOkBsCEvsBLWsBsysQkF6bADMrEiASuxCRIRErAGOQCxFg4RErAJObAXEbAGObAfErADOTAxATIWFRQGBx4BFRQGIyE1ITI2NTQmIyE1ITI2NTQmIyE1Ae5HayMbGyNrR/5EAbwkODgk/kQBvCQ4OCT+RALagEwqXxgYXypMgFRPKShPVE8oKU9UAAEAMgAAAqAC2gAoAIIAshYAACuxFwTpsggDACuxBwTptCMkFggNK7AAM7EjBOmwHjKyIyQKK7NAIyEJK7IkIwors0AkJgkrAbApL7Ah1rAlMrQgBQARBCuwJzKwIBCxGwErsAMysRIF6bAMMrEqASuxEhsRErAPOQCxIxcRErASObAkEbAPObAHErAMOTAxATI2NTQmIyE1ITIWFRQGBx4BFRQGIyE1ITI2NTQmIyEVIzUjNTM1MxUB7iQ4OCT+RAG8R2sjGxsja0f+RAG8JDg4JP75O3p6OwGWUCgpT1SATCpfGBhfKkyAVE8pKFBtbVJtbQADADIAAAKgAtoABwANADAAqACyJAAAK7ElBOmyFgMAK7EVBOm0DA0kFg0rsA4zsQwE6bAsMrAMELMPDAcOK7QDBAAPBCsBsDEvsAzWsRUkMjKxCgXpsgoMCiuzQAoLCSuwCDKwChCxAQErtAUFABoEK7AFELEpASuwETKxIAXpsBoysTIBK7EpBRESsC05sCARsB05ALEHJRESsSApOTmxDQwRErQBBAUAHSQXObEVAxESsREaOTkwMRI0NjIWFAYiJwYUFyM1ITI2NTQmIyE1ITIWFRQGBx4BFRQGIyE1ITI2NTQmKwE2NCesIy4jIy42DAxnAbwkODgk/kQBvEdrIxsbI2tH/kQBvCQ4OCS7DAwBVDIrKzIpaxIuElJQKClPVIBMKl8YGF8qTIBUTykoUBIuEgAAAAABADIAAAKgAtoAIABSALIAAAArsR4E6bIMAwArsQ8E6bQYFQAMDSuxGATpAbAhL7AD1rAJMrEbBemwEjKxIgErsRsDERKwBjkAsRgeERKwAzmwFRGwBjmwDxKwCTkwMTMiJjU0NjcuATU0NjMhFSEiBhUUFjMhFSEiBhUUFjMhFeRHayMbGyNrRwG8/kQkODgkAbz+RCQ4OCQBvIBMKl8YGF8qTIBUTykoT1RPKClPVAAAAAADADIAAAKgAtoACAARAB4AYACyGgAAK7AWM7EEBOmwDTKyHgMAK7EABOmwCTIBsB8vsB3WsQEF6bABELEHASuxCgXpsAoQsRABK7ETBemxIAErsQcBERKwGjmwChGwGDmwEBKwFjkAsQQaERKwGDkwMRMRFBYzMjY1ETMRFBYzMjY1ETcRFAYjIicGIyImNRGGNyYlN1Q3JSY3VGhJTzc3T0loAob+LCY2NiYB1P4sJjY2JgHUVP3YSmg+PmhKAigAAAAAAwAyAAACoALaAAgAEQAeAGAAshIAACuxEQTpsAAyshYDACuwGjOxDQTpsAQyAbAfL7AS1rERBemwERCxCQErsQgF6bAIELEAASuxHgXpsSABK7EJERESsBY5sAgRsBg5sAASsBo5ALEWDRESsBg5MDElETQmIyIGFREjETQmIyIGFREHETQ2MzIXNjMyFhURAkw3JiU3VDclJjdUaElPNzdPSWhUAdQmNjYm/iwB1CY2Nib+LFQCKEpoPj5oSv3YAAAAAAMAMgAAAqAC2gAIABEAIABgALIgAAArsQAE6bISAwArsREE6bQICSASDSuxCATpAbAhL7Ag1rEABemwCTKwABCxBAErsA0ysRwF6bAWMrEiASuxHAQRErAZOQCxCAARErAcObAJEbAZObARErAWOTAxNyEyNjU0JiMhNSEyNjU0JiMhJyEyFhUUBgceARUUBiMhhgFoJDg4JP6YAWgkODgk/phUAbxHayMbGyNrR/5EVE8pKE9UTygpT1SATCpfGBhfKkyAAAAAAwAyAAACoALaAA4AGwAoAJAAsg4AACuxDwTpsgADACuxJATptBslDgANK7AcM7EbBOmwFjKyGyUKK7NAGxkJK7IlGwors0AlJwkrAbApL7AO1rEPBemwJDKwDxCxGQErsCYytBgFABEEK7AcMrAYELETASuwIDKxCgXpsAQysSoBK7EKExESsAc5ALEbDxESsAo5sCURsAc5sCQSsAQ5MDETITIWFRQGBx4BFRQGIyE3ITI2NTQmKwEVIzUjNzMyNjU0JiMhFTM1MzIBvEdrIxsbI2tH/kRUAWgkODgkozuKxaMkODgk/piKOwLagEwqXxgYXypMgFRPKShPbGxUTygpT+9sAAAAAwAyAAACoALaAAcAIQAwAKAAsjAAACuxFgTpsiIDACuxDwTptBUQMCINK7AIM7EVBOmwHTKwFRCzDxUHDiu0AwQADwQrAbAxL7Aw1rEWBemwDzKwFhCxAQErtAUFABoEK7AFELEaASuwCzKxLAXpsCYysTIBK7EBFhESsBE5sRoFERKwHjmwLBGwKTkAsQcWERKxGiw5ObEQFREStAEEBQApJBc5sQ8DERKxCyY5OTAxEjQ2MhYUBiI3MjY1NCYjIRUzBhQXIxUhMjY1NCYrATY0JwEhMhYVFAYHHgEVFAYjIfkjLiMjLtIkODgk/phgDAxgAWgkODgkbgwM/rIBvEdrIxsbI2tH/kQBVDIrKzIpa1AoKU/wEi4S8E8pKFASLhIBRIBMKl8YGF8qTIAAAAMAMgAAAqAC2gAIABEAIABgALITAAArsRAE6bIfAwArsQEE6bQKBxMfDSuxCgTpAbAhL7AW1rAcMrENBemwBDKwDRCxEQErsAAysRIF6bEiASuxDRYRErAZOQCxChARErAWObAHEbAZObABErAcOTAxASEiBhUUFjMhFSEiBhUUFjMhFyEiJjU0NjcuATU0NjMhAkz+mCQ4OCQBaP6YJDg4JAFoVP5ER2sjGxsja0cBvAKGTykoT1RPKClPVIBMKl8YGF8qTIAAAwAyAAACoALaAAgAEQAiAG8AshsAACuwFzOxBQTpsA0ysh8DACuxEyEzMwGwIy+wHtaxAgXpsAIQsQgBK7AgMrEKBemwEjKwChCxEAErsRQF6bEkASuxCAIRErAbObAKEbAZObAQErAXOQCxBRsRErAZObAfEbMBERIgJBc5MDEBJxEUFjMyNjUTERQWMzI2NREHJREUBiMiJwYjIiY1EQU1MwE/uTcmJTdUNyUmN7kBDWhJTzc3T0loAQ1UAcSE/momNjYmARL+7iY2NiYBliW3/dhKaD4+aEoCKLe3AAADADIAAAKgAtoACAARACIAbwCyEwAAK7EfITMzshcDACuwGzOxDQTpsAUyAbAjL7AT1rERBemwERCxIgErsAkysSEF6bAAMrAhELEBASuxHwXpsSQBK7EiERESsBc5sCERsBk5sAESsBs5ALENExESswEREiAkFzmwFxGwGTkwMQEXETQmIyIGFQMRNCYjIgYVETcFETQ2MzIXNjMyFhURJRUjAZO5NyYlN1Q3JSY3uf7zaElPNzdPSWj+81QBFoQBliY2Nib+7gESJjY2Jv5qJbcCKEpoPj5oSv3Yt7cAAAMAMgAAAqAC2gASABsAJABYALINAAArsRQE6bISAwArsSQE6bQPEA0SDSuwHDOxDwTpsBMyAbAlL7AY1rAgMrEJBemwAzKxJgErsQkYERKwBjkAsQ8UERKwCTmwEBGwBjmwJBKwAzkwMQEyFhUUBgceARUUBiMhEyM1MwMBByEyNjU0JiMnMzI2NTQmIyEB7kdrIxsbI2tH/kS7u7u7ARyKASokODgkoKAkODgk/tYC2oBMKl8YGF8qTIABQ1QBQ/5p708pKE9UTygpTwAAAAADADIAAAKgAtoADAAfACwAhgCyGgAAK7EBBOmyHwMAK7EoBOm0HB0aHw0rsSApMzOxHATpsQAIMjKyHB0KK7NAHAsJK7IdHAors0AdKwkrAbAtL7AL1rAqMrQKBQARBCuwIDKwChCxBQErsCQysRYF6bAQMrEuASuxFgURErATOQCxHAERErAWObAdEbATObAoErAQOTAxAQchMjY1NCYrARUjNRMyFhUUBgceARUUBiMhEyM1MwMBMzI2NTQmIyEXMzUzAU6KASokODgkPDt3R2sjGxsja0f+RLu7u7sBgDwkODgk/taKKTsBQ+9PKShPbGwBl4BMKl8YGF8qTIABQ1QBQ/69TygpT+9sAAAAAAMAMgAAAqAC2gAHAB8AMgC0ALItAAArsRUE6bIyAwArsRAE6bQvMC0yDSuwCDOxLwTpsBwysC8Qsw8vBw4rtAMEAA8EKwGwMy+wL9axLTIyMrQTBQAIBCuwExCxAQErtAUFABoEK7AFELEZASuwDDKxKQXpsCMysTQBK7ETLxESsxAVLjEkFzmwARGxERQ5ObEZBRESsAg5sCkRsCY5ALEHFRESsRkpOTmxMC8RErYBBAUAERQmJBc5sRADERKxDCM5OTAxADQ2MhYUBiI3MzI2NTQmIyEXBhQXByEyNjU0JisBNjQDMhYVFAYHHgEVFAYjIRMjNTMDAWAjLiMjLmQHJDg4JP7WiQwMiQEqJDg4JAcMBUdrIxsbI2tH/kS7u7u7AVQyKysyKWtQKClP8BIuEvBPKShQEi4BVoBMKl8YGF8qTIABQ1QBQwAAAwAyAAACoALaABIAGwAkAFgAsgAAACuxIwTpsgwDACuxFQTptB0bAAwNK7AOM7EdBOmwEDIBsCUvsAPWsAkysSAF6bAYMrEmASuxIAMRErAGOQCxHSMRErADObAbEbAGObAVErAJOTAxMyImNTQ2Ny4BNTQ2MyEDMxUjEwE3ISIGFRQWMxcjIgYVFBYzIeRHayMbGyNrRwG8u7u7u/7kiv7WJDg4JKCgJDg4JAEqgEwqXxgYXypMgP69VP69AZfvTykoT1RPKClPAAAAAQAyAW0B2ALaAAUAFACyAAMAK7ADMwGwBi+xBwErADAxEzMXNzMDMkWOjkXTAtr39/6T//8AMgAAAh4C2hAGCBcAAP//ADIAAAIeAtoQBggQAAD//wAyAAAClgHsEAYIWgAA//8AMgAAApYB7BAGCEcAAP//ADIAAAKWAewQJweuAPj/fhAGCYsAAP//ADIAAAKWAewQBghhAAAAAQAyAAACoALaAB4AYwCyBwAAK7ADM7EQBOmwGTKyCwMAKwGwHy+wCtaxDQXpsA0QsRMBK7EWBemwFhCxHAErsQAF6bEgASuxEw0RErAHObAWEbAFObAcErADOQCxEAcRErAFObALEbIUHR45OTkwMSUUBiMiJwYjIiY1ETMRFBYzMjY9ATMVFBYzMjY9ATMCoGhJTzc3T0loVDcmJTdUNyUmN1SySmg+PmhKAij92CY2Nia7uyY2Nia7AAABADIAAAKgAtoAHgBjALIMAAArsgMDACuwBzOxGQTpsBAyAbAfL7Ae1rEdBemwHRCxFQErsRQF6bAUELEMASuxCwXpsSABK7EVHRESsAM5sBQRsAU5sAwSsAc5ALEZDBESshQdHjk5ObADEbAFOTAxEzQ2MzIXNjMyFhURIxE0JiMiBh0BIzU0JiMiBh0BIzJoSU83N09JaFQ3JiU3VDclJjdUAihKaD4+aEr92AIoJjY2Jru7JjY2JrsAAAEAMgAAAqAC2gAgAFIAsg0AACuxDgTpsiADACuxHwTptBYXDSANK7EWBOkBsCEvsBLWsBsysQkF6bADMrEiASuxCRIRErAGOQCxFg4RErAJObAXEbAGObAfErADOTAxATIWFRQGBx4BFRQGKwE1MzI2NTQmKwE1MzI2NTQmIyE1Ae5HayMbGyNrR4WFJDg4JIWFJDg4JP5EAtqATCpfGBhfKkyAVE8pKE9UTygpT1QAAQAyAAACoALaACQAgwCyGwAAK7EcBOmyDQMAK7EMBOm0JAQbDQ0rsSQE6bIkBAors0AkAQkrsgQkCiuzQAQCCSsBsCUvsAHWtAAFABEEK7ADMrAAELEgASuwCDKxFwXpsBEysSYBK7EAARESsRscOTmxFyARErAUOQCxJBwRErAXObAEEbAUObAMErAROTAxJSMRMxUzMjY1NCYjITUhMhYVFAYHHgEVFAYrATUzMjY1NCYrAQFqOzuEJDg4JP5EAbxHayMbGyNrR4WFJDg4JITXASxsTygpT1SATCpfGBhfKkyAVE8pKE8AAP//ADIAAAKgAtoQJgmRAAAQBweuAJ4AAAABADIAAAKgAtoAIABSALIAAAArsR4E6bIMAwArsQ8E6bQYFQAMDSuxGATpAbAhL7AD1rAJMrEbBemwEjKxIgErsRsDERKwBjkAsRgeERKwAzmwFRGwBjmwDxKwCTkwMTMiJjU0NjcuATU0NjsBFSMiBhUUFjsBFSMiBhUUFjMhFeRHayMbGyNrR4WFJDg4JIWFJDg4JAG8gEwqXxgYXypMgFRPKShPVE8oKU9UAAAAAAEAMgAAAwwC2gAsAHAAsg8AACuxHQTpsgYDACuwFTOxJwTptCwADwYNK7EsBOkBsC0vsBTWsRcF6bAXELEDASuxKQXpsikDCiuzQCkACSuwKRCxJAErsQkF6bEuASuxKQMRErEPHTk5sCQRsAY5ALEnLBESsgkkAzk5OTAxASImNTQ2MzIWFRQOAyMiLgI1ETMRFB4DMzI+BDU0JiMiFRQWMwIQWWxxXGmLDy9OhltBeXBDVCU6TUglPVw9KBQHW0V5PjMBallXXmKecE17fVM0JE6QYAF4/og+YTsmDhkyPlxXPE5raykzAAAAAQAyAAADDALaACwAbACyBgAAK7AVM7EnBOmyDwMAK7EdBOm0LAAGDw0rsSwE6QGwLS+wCdaxJAXpsCQQsSkBK7EDBemyKQMKK7NAKQAJK7ADELEWASuxFQXpsS4BK7EpJBESsgYPHTk5OQCxLCcRErIJJAM5OTkwMQEyFhUUBiMiJjU0PgMzMh4CFREjETQuAyMiDgQVFBYzMjU0JiMBLllscVxpiw8vToZbQXlwQ1QlOk1IJT1cPSgUB1tFeT4zAXBZV15innBNe31TNCROkGD+iAF4PmE7Jg4ZMj5cVzxOa2spMwAAAAEAMgAAAo4C2gArAGwAsiMAACuxCQTpshcDACuxFgTptCkEIxcNK7EpBOmyBCkKK7NABAAJKwGwLC+wJtawFjKxBgXpsAYQsQEBK7EABemwABCxDwErsR0F6bEtASuxAQYRErIJIyk5OTkAsQQJERKyDx0mOTk5MDElIzQmIyIVFBYzMj4DNTQuAysBNTMyHgIVFA4DIyImNTQ2MzIWAaJUMylra041WTYnDw4mO2E++vpgkE4kGDVLc0NwnmJeV1n8Mz55RVsuQ1BBFyVITTolVENweUEmXGRSNYtpXHFsAAAAAAEAMgAAAo4C2gArAHsAsiAAACuxBgTpshQDACuxEwTptCYBIBQNK7EmBOmyASYKK7NAASsJK7ImAQors0AmKAkrAbAsL7Aj1rATMrEDBemwAxCxKwErsCcytCoFABEEK7AqELEMASuxGgXpsS0BK7EqKxESsQYgOTkAsQEGERKyDBojOTk5MDEBIyIVFBYzMj4DNTQuAysBNTMyHgIVFA4DIyImNTQ2OwE1MxEjATFBaWtONVk2Jw8OJjthPvr6YJBOJBg1S3NDcJ5hXUE7OwFteUVbLkNQQRclSE06JVRDcHlBJlxkUjWLaVxxa/7UAAIAMgAAAo4C2gAHAC0AiwCyJwAAK7ENBOmyGwMAK7EaBOm0AwcnGw0rtAMEABIEK7MtAwcIK7EIBOkBsC4vsCrWsBoysQoF6bIKKgors0AKLQkrsAoQsQEBK7QFBQAaBCuwBRCxEwErsSEF6bEvASuxBQERErENJzk5ALEHDRESsQoqOTmwCBGxEyE5ObAtErMABAUBJBc5MDEANDYyFhQGIiciFRQWMzI+AzU0LgMrATUzMh4CFRQOAyMiJjU0NjMBKCIwIiIwWGtrTjVZNicPDiY7YT76+mCQTiQYNUtzQ3CeYl4BejAiIjAiFXlFWy5DUEEXJUhNOiVUQ3B5QSZcZFI1i2lccQAAAAABADIAAAKOAtoAKwBwALIYAAArsRUE6bIjAwArsQkE6bQpBBgjDSuxKQTpsgQpCiuzQAQACSsBsCwvsB3WsQ8F6bAPELEAASuxAQXpsAEQsQYBK7EmBemwFjKxLQErsQYBERKyCSMpOTk5ALEEKRESsQ8dOTmwCRGwJjkwMQEzFBYzMjU0JiMiDgMVFB4DOwEVIyIuAjU0PgMzMhYVFAYjIiYBHlQzKWtrTjVZNicPDiY7YT76+mCQTiQYNUtzQ3CeYl5XWQHeMz55RVsuQ1BBFyVITTolVENweUEmXGRSNYtpXHFsAAAAAQAyAAACVQLaACYAfQCyHAAAK7EJBOmyJAMAK7EjBOm0DxYcJA0rsQ8E6bIPFgors0APEwkrAbAnL7Af1rAjMrEGBemwBhCxEwErsRIF6bASELEMASuxGQXpsCUysSgBK7ESExESsQkcOTmwDBGxFiI5OQCxDwkRErIGGR85OTmxIxYRErAmOTAxEw4EFRQWMzI2NTQmIyIGFSM0NjMyFhUUBiMiJjU0PwEhNSEV/CItGA0CdU9HcDEeIiBUVUE9ZplydaOg8v5uAiMBsRQoIS0fHDdhWjAqNiYyUVtjUVKMkFq0XIxUYQAAAAABADIAAAJVAtoAJgB9ALILAAArsR4E6bICAwArsQUE6bQYEQsCDSuxGATpshgRCiuzQBgUCSsBsCcvsA7WsAEysRsF6bAbELEVASuxFAXpsBQQsSEBK7EIBemwAzKxKAErsRUbERKxEQU5ObAUEbELHjk5ALEYHhESsggOITk5ObEFERESsAE5MDEBJTUhFSEXFhUUBiMiJjU0NjMyFhUjNCYjIgYVFBYzMjY1NC4DAYv+pwIj/m7yoKN1cplmPUFVVCAiHjFwR091Ag0YLQGxyGFUjFy0WpCMUlFjW1EyJjYqMFphNxwfLSEoAAEAMgAAAlUC2gAmAH0AsiUAACuxIgTpshwDACuxCQTptA8WJRwNK7EPBOmyDxYKK7NADxIJKwGwJy+wGdawJTKxDAXpsAwQsRIBK7ETBemwExCxBgErsR8F6bAjMrEoASuxEgwRErEWIjk5sBMRsQkcOTkAsRYiERKwJjmxCQ8RErIGGR85OTkwMQE+BDU0JiMiBhUUFjMyNjUzFAYjIiY1NDYzMhYVFA8BIRUhNQGLIi0YDQJ1T0dwMR4iIFRVQT1mmXJ1o6DyAZL93QEpFCghLR8cN2FaMCo2JjJRW2NRUoyQWrRcjFRhAAAAAQAyAAADDAIjACYAdwCyDgAAK7ABM7EbBOmwFS+xFATpsCEvsQgE6bADMgGwJy+wAtaxBQXpsAUQsREBK7EYBemyGBEKK7NAGBQJK7AYELEeASuxCwXpsSgBK7ERBRESsAE5sR4YERKyCA4hOTk5ALEVGxESsREFOTmwFBGxCx45OTAxAQMjETMRNzYzMhYVFAYjIiY1NDYzFSIGFRQWMzI2NTQmIyIOAwFbyGFUjFy0WpCMUlFjW1EyJjYqMFphNxwfLSEoAVn+pwIj/m7yoKN1cplmPUFVVCAiHjFwR091Ag0YLQAAAAEAMgAAAwwCIwApAJQAsg4AACuwATOxHgTpsBkvsRQE6bIZFAors0AZGAkrshQZCiuzQBQVCSuwJC+xCATpsAMyAbAqL7AC1rEFBemwBRCxEQErsRsF6bAbELEYASuwFDK0FwUAEQQrsBcQsSEBK7ELBemxKwErsREFERKwATmxFxgRErMOCB4kJBc5ALEZHhESsREFOTmwFBGxCyE5OTAxAQMjETMRNzYzMhYVFAYjIiY1NDY3NTMVIzUGFRQWMzI2NTQmIyIOAwFbyGFUjFy0WpCMUlFjRT87OzA2KjBaYTccHy0hKAFZ/qcCI/5u8qCjdXKZZj04UQpM9FMKNB4xcEdPdQINGC0AAAABADIAAAMMAiMALgB/ALIfAAArsBIzsQUE6bAtL7QoBAANBCuwCy+xGQTpsBQyAbAvL7AT1rEWBemwFhCxIgErsQIF6bICIgorswACKwkrsAIQsQgBK7EcBemxMAErsSIWERKwEjmxCAIRErILGR85OTkAsS0FERKyAhYiOTk5sCgRswgcJQAkFzkwMSUGFRQWMzI2NTQmIyIOAwcDIxEzETc2MzIWFRQGIyImNTQ2Nz4BMzIWFAYjIgHrHTYqMFphNxwfLSEoFMhhVIxctFqQjFJRYzg0CicXIjAwIirbDykeMXBHT3UCDRgtIv6nAiP+bvKgo3VymWY9Mk0PExgwRDAAAAEAMgAAAwwCIwApAIMAshYAACuwHTOxJwTpsAovsQkE6bADL7EQBOmwHzIBsCovsB7WsR0F6bAdELENASuxBgXpsgYNCiuzQAYKCSuwBhCxAAErsRMF6bErASuxDR0RErAaObAGEbAkObAAErIQFic5OTkAsQonERKwJDmwCRGxABM5ObADErINGhw5OTkwMQE0JiMiBhUUFjMVIiY1NDYzMhYVFAYjIi4DIxEjETIeBTMyNgK4Ty8pLyYyUVtcUFGBeVc+clRLSB9UQWtJPTU0RSg1SQEYSW4wHyIgVFVBPmWYc3igXISDXP5BAiMzUmJjUjNyAAAAAQAyAAADDAIjACYAdwCyCAAAK7ADM7EhBOmwFC+xFQTpsBsvsQ4E6bABMgGwJy+wC9axHgXpsB4QsRgBK7ERBemyGBEKK7NAGBQJK7ARELEEASuxAwXpsSgBK7EYHhESsggOITk5ObEEERESsAE5ALEVFBESsQseOTmwGxGxEQU5OTAxJRMzESMRBwYjIiY1NDYzMhYVFAYjNTI2NTQmIyIGFRQWMzI+AwHjyGFUjFy0WpCMUlFjW1EyJjYqMFphNxwfLSEoygFZ/d0BkvKgo3VymWY9QVVUICIeMXBHT3UCDRgtAAAAAAEAMgAAAlUC2gAlAIYAshsAACuxCATpsiQDACuwADO0DhUbJA0rsQ4E6bIOFQors0AOEgkrAbAmL7Ae1rAjMrEFBemwBRCxEgErsREF6bARELELASuxGAXpsAAysScBK7ESBRESsCI5sBERsggbJTk5ObALErAVOQCxDggRErIFGB45OTmxJBURErIBIiU5OTkwMQEVAQ4BFRQWMzI2NTQmIyIGFSM0NjMyFhUUBiMiJjU0Nj8BJzUFAlX+p0cvcFRLbDEeIiBUVUE9ZpZ1fJxHWSzMAREC2mH+/jVFPTI6Py0qNiYyUVtjUU9xZlhTbkEgmWHHAAAAAQAyAAACVQLaACUAiACyAAAAK7AkM7IbAwArsQgE6bIRAQArsgUBACuyCwEAK7IYAQArsh4BACu0DhUAEQ0rsQ4E6QGwJi+wGNawADKxCwXpsAsQsREBK7ESBemwEhCxBQErsR4F6bAjMrEnASuxEQsRErAVObASEbIIGyU5OTmwBRKwIjkAsRUAERKyASIlOTk5MDEzNQE+ATU0JiMiBhUUFjMyNjUzFAYjIiY1NDYzMhYVFAYPARcVJTIBWUcvcFRLbDEeIiBUVUE9ZpZ1fJxHWSzM/u9hAQI1RT0yOj8tKjYmMlFbY1FPcWZYU25BIJlhxwAAAAABADIAAAMMAiMAJQBqALIOAAArsAAzsRsE6bAVL7EUBOmwIS+xCATpsAIyAbAmL7AR1rEYBemyGBEKK7NAGBQJK7AYELEeASuxCwXpsScBK7EeGBESsg4IITk5OQCxFRsRErARObAUEbILAR45OTmwIRKwBDkwMTMTAzMXNz4BMzIWFRQGIyImNTQ2MxUiBhUUFjMyNjU0JiMiBgcBMsfHYZkgQW5TWGZxT1FjW1EyJjYqLT86Mj1FNf7+ARIBEcwsWUecfHWWZj1BVVQgIh4xbEtUcC9H/qcAAAAAAQAyAAADDAIjACkAhwCyDgAAK7AAM7EfBOmwGS+xFATpshkUCiuzQBkYCSuyFBkKK7NAFBUJK7AlL7EIBOmwAjIBsCovsBHWsRwF6bAcELEYASuwFDK0FwUAEQQrsBcQsSIBK7ELBemxKwErsRcYERKzCA4fJSQXOQCxGR8RErARObAUEbIBCyI5OTmwJRKwBDkwMTMTAzMXNz4BMzIWFRQGIyImNTQ2NzUzFSM1DgEVFBYzMjY1NCYjIgYHATLHx2GZIEFuU1hmcU9RY01GOzsjHDYqLT86Mj1FNf7+ARIBEcwsWUecfHWWZj07UwdK9FYEIB0eMWxLVHAvR/6nAAEAMgAAAwwCIwArAGwAsg4AACuwADOxIQTpsBovtBUEAA0EK7AnL7EIBOmwAjIBsCwvsBHWsR4F6bIeEQorswAeGAkrsB4QsSQBK7ELBemxLQErsSQeERKyDggnOTk5ALEaIRESsREeOTmwFRG1AQsTBBwkJBc5MDEzEwMzFzc+ATMyFhUUBiMiJjU0NzYzMhYUBiMiJwYVFBYzMjY1NCYjIgYHATLHx2GZIEFuU1hmcU9RY1AYLiIwMCIkGAY2Ki0/OjI9RTX+/gESARHMLFlHnHx1lmY9bCYnMEQwGgcoHjFsS1RwL0f+pwAAAQAyAAADDAIjACUAagCyCAAAK7ACM7EhBOmwFC+xFQTpsBsvsQ4E6bAAMgGwJi+wC9axHgXpsB4QsRgBK7ERBemyGBEKK7NAGBQJK7EnASuxGB4RErIOCCE5OTkAsRQhERKwBDmwFRGyCwEeOTk5sBsSsBE5MDEBAxMjJwcOASMiJjU0NjMyFhUUBiM1MjY1NCYjIgYVFBYzMjY3AQMMx8dhmSBBblNYZnFPUWNbUTImNiotPzoyPUU1AQICI/7u/u/MLFlHnHx1lmY9QVVUICIeMWxLVHAvRwFZAAEAMgAAAwwBbgAbAFgAsBQvsQwE6bAaL7EbBOmwDzIBsBwvsBfWsQkF6bIXCQors0AXGgkrsAkQsQ4BK7ERBemxHQErsQkXERKwGTmwDhGxABQ5OQCxGgwRErAXObAbEbACOTAxAQ4HFRQWMzI9ATMVFAYjIiY1NDchNQIaAyEMHw4XCglKOqFUimtgehP+4gFuAhUIFw8aFx4QKkyefHx1fXxOOBhUAAEAMv//AwwBbQAbAFwAsgAAACuwDzOxGQTpsAwvsRQE6QGwHC+wENaxDwXpsA8QsQkBK7EXBemyFwkKK7NAFxoJK7EdASuxCQ8RErEAFDk5sBcRsBk5ALEZABESsAI5sAwRsQkXOTkwMSE+BzU0JiMiHQEjNTQ2MzIWFRQHIRUBJAMhDB8OFwoJSjqhVIprYHoTAR4BFQgXDxoXHg8rS556enZ8e083F1QAAAABADIAAAGfAtoAGwBUALIMAAArsQ0E6bIBAwArtAUTDAENK7EFBOkBsBwvsADWsAwysQMF6bADELEQASuxCAXpsR0BK7EQAxESsQUTOTkAsRMNERKxCAA5ObAFEbADOTAxNxEzETYzMhYVFAYrATUzMjU0JiMiDgYyVBc4Tnx8dnt7nkwqEB4XGQ8XCBXyAej+4hN6YGuKVKE6SgkKFw4fDCEA//8AMgAAAZ8C2hAmCasAABAHFNMApP9y//8AMgAAAZ8C2hAmCasAABAHB64AXP9sAAEAMgAAAZ8C2gAbAFoAshEAACuxDgTpshoDACu0FwkRGg0rsRcE6QGwHC+wFNaxDAXpsAwQsRkBK7EABemwDzKxHQErsRkMERKxCRc5ObAAEbACOQCxCQ4RErEAFDk5sBcRsBk5MDElLgcjIgYVFDsBFSMiJjU0NjMyFxEzAZ8CFQgXDxkXHhAqTJ57e3Z8fE44F1TyAyEMHw4XCglKOqFUimtgehMBHgAAAAABADIAAAMMAdoAHwB4ALIZAAArsREE6bAfL7EEBOmwFDKyHwQKK7NAHwEJK7IEHwors0AEAgkrAbAgL7AB1rQABQARBCuwAzKwABCxHAErsQ4F6bAOELETASuxFgXpsSEBK7EOHBESsB45sBMRsQUZOTkAsR8RERKxDhw5ObAEEbAHOTAxNyMRMxUhDgcVFBYzMj0BMxUUBiMiJjU0NyNtOzsBrQMhDB8OFwoJSjqhVIprYHoT464BLG0CFQgXDxkXHhAqTJ57e3Z8fE44FwAAAQAy/5MDDAFtAB8AeACyBQAAK7AUM7EeBOmyBR4KK7NABQMJK7IeBQors0AeAAkrsBEvsRkE6QGwIC+wFdaxFAXpsBQQsQ4BK7EcBemwHBCxAwErsAAytAIFABEEK7EhASuxDhQRErEFGTk5sBwRsB45ALEeBRESsAc5sBERsQ4cOTkwMSUzESM1IT4HNTQmIyIdASM1NDYzMhYVFAczAtE7O/5TAyEMHw4XCglKOqFUimtgehPjv/7UbQIVCBcPGRceECpMnnt7dnx8TjgXAAEAMgAAAgwC2gAfAHoAsgsAACuxDATpsh4DACu0HQQAHwQrsAAytAQSCx4NK7EEBOkBsCAvsBvWsAsysQIF6bICGwors0ACAAkrshsCCiuzQBsdCSuwAhCxDwErsQcF6bEhASuxAhsRErAaObAPEbEEEjk5ALESDBESsQcbOTmwBBGwAjkwMQEjFTYzMhYVFAYrATUzMjU0JiMiDgYHESM1IQFeaxc4Tnx8dnt7nkwqEB4XGQ8XCBUCbQEsAp/jE3pga4pUoTpKCQoXDh8MIQMBrTv//wAyAAACDALaECYJsQAAEAcU0wEX/3L//wAyAAACDALaECYJsQAAEAcHrgDK/2wAAQAyAAACDALaAB8AegCyFgAAK7ETBOmyAQMAK7QABAAfBCuwAzK0HA4WAQ0rsRwE6QGwIC+wGdaxEQXpsBEQsR4BK7EFBemwFDKyBR4KK7NABQMJK7IeBQors0AeAAkrsSEBK7EeERESsQ4cOTmwBRGwBzkAsQ4TERKxBRk5ObAcEbAeOTAxEzUhFSMRLgcjIgYVFDsBFSMiJjU0NjMyFzXgASxtAhUIFw8ZFx4QKkyee3t2fHxOOBcCnzs7/lMDIQwfDhcKCUo6oVSKa2B6E+MAAAABADIAAAIvAiMAHQBqALIKAAArsRkE6bAQL7ADM7ERBOmwATIBsB4vsAzWsBAysRYF6bIWDAors0AWEwkrsBYQsRsBK7EHBemwAjKyGwcKK7NAGwAJK7EfASuxGxYRErMECQoPJBc5ALEQGRESswAHDBMkFzkwMQE1MxUjHgEVFAYiJjU0NjcjNTMVDgEVFBYyNjU0JgFb1IA6RZXSlUU6f9M3SGWKZUgBlo1UIXJEZ5GRZ0RxIlSNDlg4RGBgRDhXAAAAAQAyAAACLwIjAB0AagCyAgAAK7ARM7EDBOmwDzKwGS+xCgTpAbAeL7AH1rACMrEbBemyGwcKK7NAGwEJK7AbELEWASuxDAXpsBAyshYMCiuzQBYSCSuxHwErsRYbERKzBAkKDyQXOQCxGQMRErMABwwTJBc5MDElFSM1My4BNTQ2MhYVFAYHMxUjNT4BNTQmIgYVFBYBBtSAOkWV0pVFOn/TN0hlimVIjY1UIXJEZ5GRZ0RxIlSNDlg4RGBgRDhXAAAAAAEAMgAAAlUB/QAdAGoAsgwAACuwEDOxFgTpshYMCiuzQBYSCSuwGy+xBwTpsAIyshsHCiuzQBsBCSsBsB4vsBHWsAEysRAF6bADMrAQELEZASuxCgXpsR8BK7EZEBESswAHDBMkFzkAsRsWERKzBAkKDyQXOTAxEyM1MxU+ATMyFhQGIyImJxUjNTMeATMyNjQmIyIGv41UIXJEZ5GRZ0RxIlSNDlg4RGBgRDhXASnUgDpFldKVRTp/0zdIZYplSAAAAP//ADIAAAJVAf0QJgm3AAAQBxTTATj/lf//ADIAAAJVAf0QJweuAPD/khAGCbcAAAABADIAAAJVAf0AHQBoALAHL7ACM7EbBOmyGwcKK7NAGwAJK7AWL7EMBOmwEDKyFgwKK7NAFhMJKwGwHi+wCtaxGQXpsBkQsQMBK7APMrECBemwETKxHwErsQMZERKzAAcMEyQXOQCxFhsRErMECQoPJBc5MDElMxUjNQ4BIyImNDYzMhYXNTMVIy4BIyIGFBYzMjYByI1UIXJEZ5GRZ0RxIlSNDlg4RGBgRDhX1NSAOkWV0pVFOn/TN0hlimVIAAABADIAAAKxAo4AIQCOALIOAAArsR0E6bAUL7AHM7EVBOmwATKyFBUKK7NAFAYJK7IVFAors0AVAwkrAbAiL7AQ1rAUMrEaBemyGhAKK7NAGhcJK7AaELEfASuxCwXpsh8LCiuzQB8BCSuwCxCxBgErsAIytAUFABEEK7EjASuxHxoRErMIDQ4TJBc5ALEUHRESswALEBckFzkwMQE1ITUzESM1Ix4BFRQGIiY1NDY3IzUzFQ4BFRQWMjY1NCYBWwEbOzvHOkWV0pVFOn/TN0hlimVIAZaNa/7UbSFyRGeRkWdEcSJUjQ5YOERgYEQ4VwABADL/lgKxAiQAIQCMALACL7AVM7EHBOmwEzKyAgcKK7NAAgQJK7IHAgors0AHBQkrsB0vsQ4E6QGwIi+wBNa0AwUAEQQrsAYysAMQsQsBK7EfBemyHwsKK7NAHwEJK7AfELEaASuxEAXpsBQyshoQCiuzQBoWCSuxIwErsRofERKzCA0OEyQXOQCxHQcRErMACxAXJBc5MDElFSEVIxEzFTMuATU0NjIWFRQGBzMVIzU+ATU0JiIGFRQWAYj+5Ts7xzpFldKVRTp/0zdIZYplSI6NawEsbSFyRGeRkWdEcSJUjQ5YOERgYEQ4VwAAAAABADIAAALAAn8AIQCKALIQAAArsBQzsRoE6bIaEAors0AaFgkrsB8vsQsE6bIfCwors0AfAQkrsAMvsAYztAQEAB8EKwGwIi+wFdawATKxFAXpsAcyshQVCiuzQBQGCSuyFRQKK7NAFQMJK7AUELEdASuxDgXpsSMBK7EdFBESswALEBckFzkAsR8aERKzCA0OEyQXOTAxASMRIzUhFSMVPgEzMhYUBiMiJicVIzUzHgEzMjY0JiMiBgEqjWsBLG0hckRnkZFnRHEiVI0OWDhEYGBEOFcBKQEbOzvHOkWV0pVFOn/TN0hlimVI//8AMgAAAsACfxAmCb0AABAHFNMBq/+U//8AMgAAAsACfxAnB64BXv+SEAYJvQAAAAEAMgAAAsACfwAhAIoAshIAACuwDTOxCATpsggSCiuzQAgLCSuwAy+xFwTpsgMXCiuzQAMhCSuwHC+wHzO0HQQAHwQrAbAiL7AV1rEGBemwBhCxDgErsBoysQ0F6bAgMrINDgors0ANHwkrsg4NCiuzQA4cCSuxIwErsQ4GERKzAAsSFyQXOQCxAwgRErMPFBUaJBc5MDEBLgEjIgYUFjMyNjczFSM1DgEjIiY0NjMyFhc1IzUhFSMRAcgPVzhEYGBEOFgOjVQicURnkZFnRHIhbQEsawEpN0hlimVIN9N/OkWV0pVFOsc7O/7lAAAAAAEAMgAAAwwCjwAkAIsAsggAACuwBDOxEQTpsBoysAAvsR8E6bAMMrIAHwors0AAIwkrsh8ACiuzQB8gCSsBsCUvsAvWsQ4F6bAOELEUASuxFwXpsBcQsR0BK7EBBemwARCxIwErsB8ytCIFABEEK7EmASuxFA4RErAIObAXEbAGObAdErAEOQCxEQgRErAGObAAEbAVOTAxAREUBiMiJwYjIiY1ETMRFBYzMjY1ETMRFBYzMjY1ETM1MxEjNQKAYElHNzdHSWBULyYkMFQwJCYvpTs7Ac/+40poPj5oSgFx/o8nNTUnARr+5ic1NScBcWz+1GwAAAAAAQAy/5QDDAIjACQAiwCyHwAAK7AMM7EkBOmyHyQKK7NAHyEJK7IkHwors0AkIgkrsBovsBEzsQQE6bAIMgGwJS+wIda0IAUAEQQrsCMysCAQsQABK7EeBemwHhCxFgErsRUF6bAVELENASuxDAXpsSYBK7EWHhESsAQ5sBURsAY5sA0SsAg5ALEaJBESsBU5sAQRsAY5MDE3ETQ2MzIXNjMyFhURIxE0JiMiBhURIxE0JiMiBhURIxUjETMVvmBJRzc3R0lgVC8mJDBUMCQmL6U7O1QBHUpoPj5oSv6PAXEnNTUn/uYBGic1NSf+j2wBLGwAAAEAMgAAAsEC2gAkAI0AsgwAACuxDQTpsiEDACu0IAQAHwQrsCMytBUWDCENK7EVBOm0AB4MIQ0rsQAE6QGwJS+wH9awDDKxAAXpsgAfCiuzQAAjCSuyHwAKK7NAHyAJK7AAELERASuwGjKxCAXpsAQysSYBK7ERABESsBU5sAgRsAY5ALEVDRESsAg5sBYRsAY5sB4SsAQ5MDETITIWFRQHFhUUBiMhNSEyNjU0JiMhNSEyNjU0JiMhNSM1IRUj8gEdSmg+PmhK/o8BcSc1NSf+5gEaJzU1J/6PbAEsbAJOYElHNzdHSWBULyYkMFQwJCYvpTs7AAAAAQAyAAACwQLaACgArgCyDAAAK7ENBOmyJQMAK7QkBAAfBCuwJzK0FRoMJQ0rsRUE6bIVGgors0AVFwkrshoVCiuzQBoYCSu0ACIMJQ0rsQAE6QGwKS+wI9awDDKxAAXpsgAjCiuzQAAnCSuyIwAKK7NAIyQJK7AAELEXCyu0FgUAEQQrsBkysBYQsREBK7AeMrEIBemwBDKxKgErsQgRERKwBjkAsRUNERKwCDmwGhGwBjmwIhKwBDkwMRMhMhYVFAcWFRQGIyE1ITI2NTQmKwEVIxEzFTMyNjU0JiMhNSM1IRUj8gEdSmg+PmhK/o8BcSc1NSfgOzvgJzU1J/6PbAEsbAJOYElHNzdHSWBULyYkMG0BLGswJCYvpTs7AAAAAgAyAAACwQLaAAcALADKALIUAAArsRUE6bIpAwArtCgEAB8EK7ArMrQdHhQpDSuxHQTpsB0QsxIdBw4rtAMEABIEK7QIJhQpDSuxCATpAbAtL7An1rAUMrEIBemyCCcKK7NACCsJK7InCAors0AnKAkrsCcQsAEg1hG0BQUAGgQrsAgQsRkBK7AiMrEQBemwDDKxLgErsQgBERKxAgc5ObAFEbEDBjk5sBkSsB05sBARsA45ALEHFRESsRAZOTmxHh0RErQBBAUADiQXObEmAxESsQwiOTkwMRI0NjIWFAYiEyEyFhUUBxYVFAYjITUhMjY1NCYrATUzMjY1NCYjITUjNSEVI8IiMCIiMA4BHUpoPj5oSv6PAXEnNTUnr68nNTUn/o9sASxsAQ8wIiIwIgFhYElHNzdHSWBULyYkMFQwJCYvpTs7AAEAMgAAAsEC2gAkAI0AshoAACuxFwTpsgMDACu0AgQAHwQrsAUytBEOGgMNK7ERBOm0JAgaAw0rsSQE6QGwJS+wHdawITKxFAXpsAsysBQQsQABK7EGBemwGDKyBgAKK7NABgUJK7IABgors0AAAgkrsSYBK7EUHRESsB85sAARsA85ALERFxESsB05sA4RsB85sAgSsCE5MDEBNSM1IRUjFSEiBhUUFjMhFSEiBhUUFjMhFSEiJjU0NyY1NDYzAgFsASxs/o8nNTUnARr+5ic1NScBcf6PSmg+PmhKAk5ROzulLyYkMFQwJCYvVGBJRzc3R0lgAAAAAQAyAAADDALaABsAYwCyDAAAK7EaBOmyEwMAK7AEM7ESBOmwBTIBsBwvsA7WsRcF6bIOFwors0AOEwkrsBcQsQABK7EJBemyCQAKK7NACQQJK7EdASuxABcRErELDDk5ALESGhESswEJDhYkFzkwMQERNDYzFSIGFREUBiImNRE0JiM1MhYVERQWMjYCblxCHyur8KsrH0Jceqp6ASIBFkNfVC0g/ul4qqp4ARcgLVRfQ/7qVXl5AAEAMgAAAwwC2gAbAGMAsgQAACuwEzOxBQTpsBIysgwDACuxGgTpAbAcL7AI1rEBBemyCAEKK7NACAQJK7ABELEWASuxDwXpsg8WCiuzQA8TCSuxHQErsRYBERKxCww5OQCxGgURErMBCQ4WJBc5MDETERQGIzUyNjURNDYyFhURFBYzFSImNRE0JiIG0FxCHyur8KsrH0Jceqp6Abj+6kNfVC0gARd4qqp4/ukgLVRfQwEWVXl5AAABADIAAAMMAtoAGwBbALITAAArsgQDACu0DxYTBA0rsQ8E6bQIARMEDSuxCATpAbAcL7AT1rAEMrESBemwBTKwEhCxGgErsQwF6bEdASuxGhIRErMBCQ4WJBc5ALEBFhESsQsMOTkwMQEhIiY1MxQWMyEyFhQGIyEiBhUjNDYzITI2NCYB6v7qQ19ULSABF3iqqnj+6SAtVF9DARZVeXkCPFxCHyur8KsrH0Jceqp6//8AMgAAAwwC2hAnB9EAlv8pEAYJyQAA//8AMgAAAwwC2hAnB64A7gAAEAYJyQAAAAEAMgAAAwwC2gAbAFsAsgUAACuyEgMAK7QJAAUSDSuxCQTptA4XBRINK7EOBOkBsBwvsAzWsRoF6bAaELEFASuwEjKxBAXpsBMysR0BK7EFGhESswEJDhYkFzkAsRcAERKxCww5OTAxJSEyFhUjNCYjISImNDYzITI2NTMUBiMhIgYUFgFUARZDX1QtIP7peKqqeAEXIC1UX0P+6lV5eZ5cQh8rq/CrKx9CXHqqegAAAQAyAW0BeQLaAAcAPgCyAAMAK7QHBAAfBCuwBS+0AgQAHwQrAbAIL7AF1rAAMrQEBQAHBCuwATKxCQErsQQFERKyAgMGOTk5ADAxEyEDMxUhEyMyAUfZ2f650tIC2v7JNgE3AAMAMgEnAXkDIAARABQAFwBpALIQAwArsAIztA8EAB8EK7AVMrIQDwors0AQAAkrsAsvsAcztBQEAB8EK7AFMrILFAors0ALCgkrAbAYL7AK1rIADRIyMjK0CQUAEQQrsgEEFTIyMrEZASsAsQ8UERKzBA0TFiQXOTAxEzMVMwcVMxUjFSM1Izc1IzUzETUHExU3tzaMjIyMNoWFhYUXTRcDIEbJbjZGRsVyNv7JISEBASIi//8AMgAAAwwC2hAmCccAABAHB7EA2AAA//8AMgAAAwwC2hAmCcgAABAHCXUA1v5S//8AMgAAAwwC2hAmCckAABAGFNQyAAAA//8AMgAAAwwC2hAnB9EBkP8pEAYJ0QAA//8AMgAAAwwC2hAnB64BrgAAEAYJ0QAA//8AMgAAAwwC2hAmCcwAABAHFNUB4AAAAAEAMgAAAwwC2gAqAI8AsgcAACuwAzOxFgTpsB8yshYHCiuzQBYaCSuyDwMAK7AmM7EOBOmwJzIBsCsvsArWsRMF6bIKEwors0AKDwkrsBMQsRkBK7EcBemwHBCxIgErsQAF6bIAIgors0AAJgkrsSwBK7EZExESsAc5sBwRsAU5sCISsAM5ALEWBxESsAU5sA4RswoAEiMkFzkwMSUUBiMiJwYjIiY1ETQmIzUyFhURFBYzMjY1ETMRFBYzMjY1ETQ2MxUiBhUCwl9IRTc3RUhfKx9CXC4lJC5ULiQlLlxCHyuyS2c+PmdLAYcgLVRfQ/56JzU1JwFx/o8nNTUnAYZDX1QtIAAAAAEAMgAAAwwC2gAqAI8AsiYAACuwDzOxJwTpsA4ysgMDACuwBzOxHwTpsBYysh8DCiuzQB8bCSsBsCsvsCrWsSMF6bIqIwors0AqJgkrsCMQsRsBK7EaBemwGhCxEgErsQsF6bILEgors0ALDwkrsSwBK7EbIxESsAM5sBoRsAU5sBISsAc5ALEfJxESswoAEiMkFzmwAxGwBTkwMRM0NjMyFzYzMhYVERQWMxUiJjURNCYjIgYVESMRNCYjIgYVERQGIzUyNjV8X0hFNzdFSF8rH0JcLiUkLlQuJCUuXEIfKwIoS2c+PmdL/nkgLVRfQwGGJzU1J/6PAXEnNTUn/npDX1QtIAAAAAEAMgAAApwC2gAqAH0Asg8AACuyJgMAK7QLEg8mDSuxCwTptBobDyYNK7EaBOm0KiMPJg0rsSoE6QGwKy+wD9awJjKxDgXpsCcysA4QsRYBK7AfMrEHBemwAzKxLAErsRYOERK0CgASGiMkFzmwBxGwBTkAsRoSERKwBzmwGxGwBTmwIxKwAzkwMQEyFhUUBxYVFAYjISIGFSM0NjMhMjY1NCYjITUhMjY1NCYjISImNTMUFjMB6ktnPj5nS/7pIC1UX0MBFic1NSf+/wEBJzU1J/7qQ19ULSACkF9IRTc3RUhfKx9CXC4lJC5ULiQlLlxCHysAAAAAAQAyAAACnALaAC4ArgCyDwAAK7IqAwArtAsSDyoNK7ELBOm0Gh8PKg0rsRoE6bIaHwors0AaHAkrsh8aCiuzQB8dCSu0LicPKg0rsS4E6QGwLy+wD9awKjKxDgXpsCsysA4QsRwBK7QbBQARBCuwHjKwGxCxFgErsCMysQcF6bADMrEwASuxGxwRErMLEicuJBc5sBYRswoTACYkFzmwBxKwBTkAsRoSERKwBzmwHxGwBTmwJxKwAzkwMQEyFhUUBxYVFAYjISIGFSM0NjMhMjY1NCYrARUjETMVMzI2NTQmIyEiJjUzFBYzAepLZz4+Z0v+6SAtVF9DARYnNTUn4Ts74Sc1NSf+6kNfVC0gApBfSEU3N0VIXysfQlwuJSQubAEsbC4kJS5cQh8rAAAA//8AMgAAApwC2hAmCdcAABAGB64WAAAAAAEAMgAAApwC2gAqAH0AsicAACuyDgMAK7QAIicODSuxAATptBwZJw4NK7EcBOm0ChMnDg0rsQoE6QGwKy+wA9awBzKxHwXpsBYysB8QsScBK7AOMrEmBemwDzKxLAErsR8DERKwBTmwJxG0CgASGiMkFzkAsRwiERKwAzmwGRGwBTmwExKwBzkwMTciJjU0NyY1NDYzITI2NTMUBiMhIgYVFBYzIRUhIgYVFBYzITIWFSM0JiPkS2c+PmdLARcgLVRfQ/7qJzU1JwEB/v8nNTUnARZDX1QtIEpfSEU3N0VIXysfQlwuJSQuVC4kJS5cQh8rAAADADIAAAMMAtoAIAApADIAswCyBwAAK7ADM7EvBOmwJjKyDwMAK7AcM7EOBOmwHTK0EysHDw0rsCEzsRME6bAXMrITKwors0ATFQkrAbAzL7AK1rEsBemwEjKyCiwKK7NACg8JK7AsELEyASuwFDKxIwXpsBYysCMQsSkBK7AYMrEABemyACkKK7NAABwJK7E0ASuxMiwRErAHObAjEbAFObApErADOQCxLwcRErAFObArEbEKADk5sQ4TERKxCyA5OTAxJRQGIyInBiMiJjURNCYjNTIWHQEzNTMVMzU0NjMVIgYVByMRFBYzMjY1AyMRFBYzMjY1AsJfSEU3N0VIXysfQlylVKVcQh8rVKUuJCUu+aUuJSQusktnPj5nSwGHIC1UX0MVY2MVQ19ULSBq/uMnNTUnAR3+4yc1NScAAAMAMgAAAwwC2gAgACkAMgCzALIcAAArsA8zsR0E6bAOMrIDAwArsAczsSYE6bAvMrQYIRwDDSuwKjOxGATpsBMyshghCiuzQBgWCSsBsDMvsCDWsRkF6bAhMrIgGQors0AgHAkrsBkQsRYBK7AiMrEVBemwKjKwFRCxEgErsCsysQsF6bILEgors0ALDwkrsTQBK7EWGRESsAM5sBURsAU5sBISsAc5ALEYHRESsQsgOTmxJiERErEKADk5sAMRsAU5MDETNDYzMhc2MzIWFREUFjMVIiY9ASMVIzUjFRQGIzUyNjU3MxE0JiMiBhUTMxE0JiMiBhV8X0hFNzdFSF8rH0JcpVSlXEIfK1SlLiQlLvmlLiUkLgIoS2c+PmdL/nkgLVRfQxVjYxVDX1QtIGoBHSc1NSf+4wEdJzU1JwAAAwAyAAACnALaACAAKQAyAKsAsg8AACuyHAMAK7QLEg8cDSuwKzOxCwTptBUWDxwNK7AiM7EVBOmwKjK0IBkPHA0rsCEzsSAE6QGwMy+wD9awHDKxDgXpsB0ysA4QsRMBK7AXMrErBemwITKyEysKK7NAExUJK7ArELEvASuwJjKxBwXpsAMysTQBK7ETDhESsQsgOTmxLysRErEKADk5sAcRsAU5ALEVEhESsAc5sBYRsAU5sBkSsAM5MDEBMhYVFAcWFRQGIyEiBhUjNDY7ATUjNTM1IyImNTMUFjMXFTMyNjU0JiMHFTMyNjU0JiMB6ktnPj5nS/7pIC1UX0MVY2MVQ19ULSBqrSc1NSetrSc1NScCkF9IRTc3RUhfKx9CXKVUpVxCHytUpS4kJS75pS4lJC4AAAAAAwAyAAACnALaAAwAGQA6ANkAsikAACuyNgMAK7QlLCk2DSuwATOxJQTptC8wKTYNK7EOEjMzsS8E6bEACDIysi8wCiuzQC8LCSuyMC8KK7NAMBAJK7Q6Myk2DSuwDTOxOgTpAbA7L7Ap1rA2MrEoBemwNzKwKBCxLQErsDEysQEF6bANMrItAQors0AtLwkrsAEQsQsBK7APMrQKBQARBCuwETKwChCxBQErsBYysSEF6bAdMrE8ASuxLSgRErElOjk5sQUKERKxGiQ5ObAhEbAfOQCxLywRErAhObAwEbAfObAzErAdOTAxARUzMjY1NCYrARUjNScVMzUzFTMyNjU0JiM1MhYVFAcWFRQGIyEiBhUjNDY7ATUjNTM1IyImNTMUFjMBPa0nNTUnMTtBQTsxJzU1J0tnPj5nS/7pIC1UX0MVY2MVQ19ULSABQ6UuJSQubGz5pWxsLiQlLlRfSEU3N0VIXysfQlylVKVcQh8rAAAAAwAyAAACnALaAAcAIABBAOQAsjAAACuyPQMAK7QsMzA9DSuwGTOxLATptDY3MD0NK7AMM7E2BOmwIDKwNhCzDzYHDiu0AwQADwQrtEE6MD0NK7ASM7FBBOkBsEIvsDDWsD0ysS8F6bA+MrAvELE0ASuwODKxGQXpsBMysjQZCiuzQDQ3CSuwGRCxAQErtAUFABoEK7AFELEdASuwDzKxKAXpsCQysUMBK7E0LxESsSxBOTmwGRGwFjmxHQURErIIISs5OTmwKBGwJjkAsQczERKxHSg5ObA2EbAYObA3ErUBBAUAFCYkFzmxOgMRErEPJDk5MDEANDYyFhQGIjc2NCc3MjY1NCYrARUGFRQXFTMyNjU0JiMRMhYVFAcWFRQGIyEiBhUjNDY7ATUjNTM1IyImNTMUFjMBUCMuIyMuZAwMEyc1NSetDAytJzU1J0tnPj5nS/7pIC1UX0MVY2MVQ19ULSABVDIrKzIpGRIuEgEuJCUuphIXGBKlLiUkLgFNX0hFNzdFSF8rH0JcpVSlXEIfKwADADIAAAKcAtoAIAApADIAqwCyHQAAK7IOAwArtAApHQ4NK7AYM7EABOm0IzIdDg0rsBQzsSME6bAWMrQKLB0ODSuwEjOxCgTpAbAzL7AD1rAHMrEmBemwLzKwJhCxIQErsCoysRgF6bATMrIYIQors0AYFgkrsBgQsR0BK7AOMrEcBemwDzKxNAErsSYDERKwBTmwIRGxCgA5ObEdGBESsQsgOTkAsSMpERKwAzmwMhGwBTmwLBKwBzkwMTciJjU0NyY1NDYzITI2NTMUBisBFTMVIxUzMhYVIzQmIyc1IyIGFRQWMzc1IyIGFRQWM+RLZz4+Z0sBFyAtVF9DFWNjFUNfVC0gaq0nNTUnra0nNTUnSl9IRTc3RUhfKx9CXKVUpVxCHytUpS4kJS75pS4lJC4AAAMAMgAAAdsC2gAjACoANACyALIBAAArshMDACu0IywBEw0rsAgzsSME6bQSJQETDSuwGzOxEgTpsBUyAbA1L7AP1rEoBemwKBCwBSDWEbEEBemwBC+xBQXpsCgQsQEBK7IIEiQyMjK0AAUAEQQrshQbKzIyMrAAELEvASuxIAXpsCAQsBgg1hGxGQXpsBkvsRgF6bE2ASuxDwQRErADOQCxIwERErACObAsEbADObAlErUEDxggJCskFzmwEhGwFjkwMSEjNSYnMx4BFzUuBDU0Njc1MxUeARcjJicVFhcWFRQGBwM1DgEVFBYXFT4BNTQuAwEiO68GWAUnMQcWOi0kW007T1QBWANJVhxHY1Y7JismZi01DA8gElUMpik0B6wBBBQeOiZCVAhWVQZTR0YMohUQJVFGVwgBTpQGKR4ZIm+eBSwgEBgODQUAAwAyAAADDALaAAgAEQA2AMQAshkAACuwFTOxBQTpsA4ysiEDACuxKTIzM7EgBOmyJyszMjIytCUBGSENK7AJM7ElBOmwLTIBsDcvsBzWsQIF6bAkMrIcAgors0AcIQkrsAIQsQgBK7AmMrELBemwLDKyCwgKK7NACysJK7IICwors0AIKAkrsAsQsREBK7AuMrESBemyEhEKK7NAEjIJK7E4ASuxCAIRErAZObALEbAXObARErAVOQCxBRkRErAXObABEbESHDk5sSAlERKxHTY5OTAxASMRFBYzMjY1EyMRFBYzMjY1MxQGIyInBiMiJjURNCYjNTIWHQEzNSM1IRUjFTM1NDYzFSIGFQF1pS4lJC75pS4kJS5UX0hFNzdFSF8rH0JcpVoBCFqlXEIfKwHP/uMnNTUnAR3+4yc1NSdLZz4+Z0sBhyAtVF9DFWNUVGMVQ19ULSAAAAAAAwAyAAADDALaAAgAEQA2AMQAsjIAACuxISkzM7EzBOmyICcrMjIyshUDACuwGTOxDgTpsAUytC4JMhUNK7AAM7EuBOmwJTIBsDcvsDbWsS8F6bAJMrI2Lwors0A2MgkrsC8QsSwBK7AKMrEnBemwADKyJywKK7NAJykJK7IsJwors0AsKgkrsCcQsSQBK7ABMrEdBemyHSQKK7NAHSEJK7E4ASuxLC8RErAVObAnEbAXObAkErAZOQCxLjMRErEdNjk5sQ4JERKxEhw5ObAVEbAXOTAxATMRNCYjIgYVAzMRNCYjIgYVIzQ2MzIXNjMyFhURFBYzFSImPQEjFTMVITUzNSMVFAYjNTI2NQHJpS4lJC75pS4kJS5UX0hFNzdFSF8rH0JcpVr++FqlXEIfKwELAR0nNTUn/uMBHSc1NSdLZz4+Z0v+eSAtVF9DFWNUVGMVQ19ULSAAAAAAAwAyAAACnALaAAgAEQA2ALwAsiEAACuyMgMAK7QdJCEyDSuwATOxHQTptCcsITINK7AKM7EnBOmwADKyJywKK7NAJykJK7IsJwors0AsKgkrtDYvITINK7AJM7E2BOkBsDcvsCHWsSkyMjKxIAXpsicrMzIyMrAgELElASuwLTKxAQXpsAkysAEQsQUBK7AOMrEZBemwFTKxOAErsSUgERKxHTY5ObEFARESsRIcOTmwGRGwFzkAsSckERKwGTmwLBGwFzmwLxKwFTkwMQEVMzI2NTQmIycVMzI2NTQmIzUyFhUUBxYVFAYjISIGFSM0NjsBNSMVIxEzFTM1IyImNTMUFjMBPa0nNTUnra0nNTUnS2c+PmdL/ukgLVRfQxVjVFRjFUNfVC0gAUOlLiUkLvmlLiQlLlRfSEU3N0VIXysfQlylWgEIWqVcQh8rAAAAAwAyAAACnALaACQAMQA+AOAAsh4AACuyCgMAK7QaIR4KDSuwJjOxGgTptCQEHgoNK7EzNzMzsSQE6bElLTIysiQECiuzQCQBCSuzQCQwCSuyBCQKK7NABAIJK7NABDUJK7QOBx4KDSuwMjOxDgTpAbA/L7Ae1rEBCjIysR0F6bIAAwsyMjKwHRCxIgErsAUysSYF6bAyMrAmELEwASuwNDK0LwUAEQQrsDYysC8QsSoBK7A7MrEWBemwEjKxQAErsSIdERKxDho5ObEqLxESsRkPOTmwFhGwFDkAsSQhERKwFjmwBBGwFDmwBxKwEjkwMTcjETMVMzUjIiY1MxQWMyEyFhUUBxYVFAYjISIGFSM0NjsBNSMzFTMyNjU0JisBFSM1JxUzNTMVMzI2NTQmI4ZUVGMVQ19ULSABF0tnPj5nS/7pIC1UX0MVY7etJzU1JzE7QUE7MSc1NSfpAQhapVxCHytfSEU3N0VIXysfQlylpS4lJC5sbPmlbGwuJCUuAAAAAAMAMgAAApwC2gAkACwARQD1ALIfAAArsgsDACu0GyIfCw0rsD4zsRsE6bQABR8LDSuwMTOxAATpsEUysgAFCiuzQAACCSuyBQAKK7NABQMJK7AAELMPACwOK7QoBAAPBCu0DwgfCw0rsDczsQ8E6QGwRi+wH9axAgsyMrEeBemyAAQMMjIysB4QsSMBK7AGMrE+BemwODKwPhCxJgErtCoFABoEK7AqELFCASuwNDKxFwXpsBMysUcBK7EjHhESsQ8bOTmwPhGwOzmxQioRErIaEC05OTmwFxGwFTkAsSwiERKxF0I5ObAAEbA9ObAFErUVJSYpKjkkFzmxCCgRErETNDk5MDETFSMRMxUzNSMiJjUzFBYzITIWFRQHFhUUBiMhIgYVIzQ2OwE1NjQ2MhYUBiI3NjQnNzI2NTQmKwEVBhUUFxUzMjY1NCYjhlRUYxVDX1QtIAEXS2c+PmdL/ukgLVRfQxVnIy4jIy5kDAwTJzU1J60MDK0nNTUnAUNaAQhapVxCHytfSEU3N0VIXysfQlylETIrKzIpGRIuEgEuJCUuphIXGBKlLiUkLgAAAAMAMgAAApwC2gAIABEANgC8ALIzAAArsiADACu0EhEzIA0rsC4zsRIE6bQLCDMgDSuwJjOxCwTpsCwysgsICiuzQAsrCSuyCAsKK7NACCgJK7QcAjMgDSuwJDOxHATpAbA3L7AV1rAZMrEOBemwBTKwDhCxCQErsAAysS4F6bAlMrAuELEzASuyICcrMjIysTIF6bEhKTIysTgBK7EOFRESsBc5sAkRsRIcOTmxMy4RErEdNjk5ALELERESsBU5sAgRsBc5sAISsBk5MDEBNSMiBhUUFjMXNSMiBhUUFjMVIiY1NDcmNTQ2MyEyNjUzFAYrARUzNTMRIzUjFTMyFhUjNCYjAZGtJzU1J62tJzU1J0tnPj5nSwEXIC1UX0MVY1RUYxVDX1QtIAGXpS4lJC75pS4kJS5UX0hFNzdFSF8rH0JcpVr++FqlXEIfKwAAAAEAMgAAAwwC2gAuAKAAshYAACuwEjOxJQTpsAMysh4DACuxCiszM7EdBOmyCyktMjIyAbAvL7AZ1rEiBemyGSIKK7NAGR4JK7AiELEoASuxAAXpsgAoCiuzQAAtCSuyKAAKK7NAKCoJK7AAELEGASuxDwXpsg8GCiuzQA8KCSuxMAErsSgiERKwFjmwABGwFDmwBhKwEjkAsSUWERKwFDmwHRGzBw8ZISQXOTAxJRQWMzI2NRE0NjMVIgYVERQGIyInBiMiJjURNCYjNTIWFREUFjMyNjURIzUhFSMByS4kJS5cQh8rX0hFNzdFSF8rH0JcLiUkLloBCFqyJzU1JwGGQ19ULSD+eUtnPj5nSwGHIC1UX0P+eic1NScB1FRUAAEAMgAAAwwC2gAuAKAAsgoAACuxHiszM7ELBOmyHSktMjIyshIDACuwFjOxAwTpsCUyAbAvL7AO1rEHBemyDgcKK7NADgoJK7AHELEuASuxKQXpsikuCiuzQCkrCSuyLikKK7NALiwJK7ApELEhASuxGgXpshohCiuzQBoeCSuxMAErsS4HERKwEjmwKRGwFDmwIRKwFjkAsQMLERKzBw8ZISQXObASEbAUOTAxATQmIyIGFREUBiM1MjY1ETQ2MzIXNjMyFhURFBYzFSImNRE0JiMiBhURMxUhNTMBdS4kJS5cQh8rX0hFNzdFSF8rH0JcLiUkLlr++FoCKCc1NSf+ekNfVC0gAYdLZz4+Z0v+eSAtVF9DAYYnNTUn/ixUVAAAAAABADIAAAKcAtoALgCYALIkAAArshADACu0ICckEA0rsSAE6bQABSQQDSuxAATpsgAFCiuzQAACCSuyBQAKK7NABQMJK7QUDSQQDSuxFATpAbAvL7Ak1rECEDIysSMF6bIABBEyMjKwIxCxKwErsAkysRwF6bAYMrEwASuxKyMRErMNFR8nJBc5sBwRsBo5ALEAJxESsBw5sAURsBo5sA0SsBg5MDETFSMRMxUhMjY1NCYjISImNTMUFjMhMhYVFAcWFRQGIyEiBhUjNDYzITI2NTQmI4ZUVAFkJzU1J/7qQ19ULSABF0tnPj5nS/7pIC1UX0MBFic1NScBQ1oBCFouJCUuXEIfK19IRTc3RUhfKx9CXC4lJC4AAQAyAAACnALaADYAywCyKAAAK7IUAwArtCQrKBQNK7EkBOm0AAUoFA0rsAkzsQAE6bAyMrIABQors0AAAgkrs0AANQkrsgUACiuzQAUDCSuzQAUHCSu0GBEoFA0rsRgE6QGwNy+wKNaxAhQyMrEnBemyAAQVMjIysCcQsTUBK7AGMrQ0BQARBCuwCDKwNBCxLwErsA0ysSAF6bAcMrE4ASuxNScRErMRGCQrJBc5sS80ERKzEBkjLCQXObAgEbAeOQCxACsRErAgObAFEbAeObARErAcOTAxExUjETMVMzUzFTMyNjU0JiMhIiY1MxQWMyEyFhUUBxYVFAYjISIGFSM0NjMhMjY1NCYrARUjNYZUVHo7ryc1NSf+6kNfVC0gARdLZz4+Z0v+6SAtVF9DARYnNTUnrzsBQ1oBCFpsbC4kJS5cQh8rX0hFNzdFSF8rH0JcLiUkLmxsAAAAAwAyAAACnALaAAcANAA+AOEAsioAACuyFgMAK7QmLSoWDSuxJgTptDU6KhYNK7ALM7E1BOmwCDKyNToKK7NANTcJK7I6NQors0A6OAkrsDUQsw81Bw4rtAMEAA8EK7QaEyoWDSuxGgTpAbA/L7Aq1rEWNzIysSkF6bIXNTkyMjK0PQUADwQrsCkQsQEBK7QFBQAaBCuwBRCxMQErsA8ysSIF6bAeMrFAASuxAT0RErUTGiYtOz4kFzmxMQURErQIEhslLiQXObAiEbAgOQCxBy0RErEiMTk5sTo1ERK0AQQFACAkFzmxEwMRErEPHjk5MDESNDYyFhQGIjc2NCczMjY1NCYjISImNTMUFjMhMhYVFAcWFRQGIyEiBhUjNDYzITI2NTQmIyEVIxEzFTMGFBfWIy4jIy5kDAyNJzU1J/7qQ19ULSABF0tnPj5nS/7pIC1UX0MBFic1NSf+nFRUPQwMAVQyKysyKRgSMBIuJCUuXEIfK19IRTc3RUhfKx9CXC4lJC5aAQhaEjASAAAAAAEAMgAAApwC2gAuAJgAshEAACuyIwMAK7QVDBEjDSuxFQTptAYuESMNK7EGBOmyBi4KK7NABgQJK7IuBgors0AuAQkrtB8oESMNK7EfBOkBsC8vsBjWsBwysQkF6bArMrAJELERASuyAAQjMjIysRAF6bECJDIysTABK7EJGBESsBo5sBERsw0VHyckFzkAsQYMERKwGDmwLhGwGjmwKBKwHDkwMQE1MxEjNSEiBhUUFjMhMhYVIzQmIyEiJjU0NyY1NDYzITI2NTMUBiMhIgYVFBYzAkhUVP6cJzU1JwEWQ19ULSD+6UtnPj5nSwEXIC1UX0P+6ic1NScBl1r++FouJCUuXEIfK19IRTc3RUhfKx9CXC4lJC4AAAAAAwAyAAACoALaAAgAEQAmAIwAshsAACuwFzOxBQTpsA0ysiMDACuxEx8zM7EiBOmwJTIBsCcvsB7WsQIF6bACELEIASuwIDKxCgXpsBIysgoICiuzQAolCSuyCAoKK7NACCIJK7AKELEQASuxFAXpsSgBK7EIAhESsBs5sAoRsBk5sBASsBc5ALEFGxESsBk5sCIRswEREiAkFzkwMQEnERQWMzI2NRMRFBYzMjY1EQclERQGIyInBiMiJjURBTUjNSEVIwE/uTcmJTdUNyUmN7kBDWhJTzc3T0loAQ1aAQhaAcSE/momNjYmARL+7iY2NiYBliW3/dhKaD4+aEoCKLdjVFQAAAAAAwAyAAACoALaAAgAEQAmAIwAsiQAACuxEx8zM7ElBOmwITKyFwMAK7AbM7ENBOmwBTIBsCcvsBPWsREF6bARELEmASuwCTKxIQXpsAAysiEmCiuzQCEjCSuyJiEKK7NAJiQJK7AhELEBASuxHwXpsSgBK7EmERESsBc5sCERsBk5sAESsBs5ALENJRESswEREiAkFzmwFxGwGTkwMQEXETQmIyIGFQMRNCYjIgYVETcFETQ2MzIXNjMyFhURJRUzFSE1MwGTuTcmJTdUNyUmN7n+82hJTzc3T0lo/vNa/vhaARaEAZYmNjYm/u4BEiY2Nib+aiW3AihKaD4+aEr92LdjVFQAAAAAAwAyAAACoALaABYAHwAoAIwAshUAACuxGATpsgcDACuxKATptAAFFQcNK7AgM7EABOmwFzKyAAUKK7NAAAIJK7IFAAors0AFAwkrAbApL7AC1rEHFTIysQEF6bAEMrABELEcASuwJDKxEQXpsAsysSoBK7EcARESswYWGCgkFzmwERGwDjkAsQAYERKwETmwBRGwDjmwKBKwCzkwMRMVIxEzFTMDITIWFRQGBx4BFRQGIyETMwchMjY1NCYjJzMyNjU0JiMhhlRUZ7sBvEdrIxsbI2tH/kS7YYoBKiQ4OCSgoCQ4OCT+1gFDWgEIWgFDgEwqXxgYXypMgAFD708pKE9UTygpTwAAAwAyAAACoALaAAwAIwAwALIAsiIAACuxBQTpshQDACuxKwTptA0SIhQNK7EkLDMzsQ0E6bEAAzIysg0SCiuzQA0CCSuzQA0PCSuyEg0KK7NAEi4JK7NAEhAJKwGwMS+wD9axFCIyMrEOBemwETKwDhCxAgErsC0ytAEFABEEK7AvMrABELEJASuwJzKxHgXpsBgysTIBK7ECDhESswUTIyskFzmxHgkRErAbOQCxDQURErAeObASEbAbObArErAYOTAxARUjNSMHITI2NTQmIyEVIxEzFTMDITIWFRQGBx4BFRQGIyETJTI2NTQmIyEXMzUzFQGyOymKASokODgk/phUVGe7AbxHayMbGyNrR/5EuwEBJDg4JP7Wiik7AUNsbO9PKShPWgEIWgFDgEwqXxgYXypMgAFDVE8oKU/vbGwAAAAAAwAyAAACoALaAAcAHwA2AMYAsjUAACuxGATpsicDACuxEwTptCAlNScNK7ALM7EgBOmwCDKyICUKK7NAICIJK7IlIAors0AlIwkrsCAQsw8gBw4rtAMEAA8EKwGwNy+wItaxJzUyMrEhBemwJDKwIRCxAQErtAUFABoEK7AFELEcASuwDzKxMQXpsCsysTgBK7EBIREStBMUGCY2JBc5sRwFERKwCDmwMRGwLjkAsQcYERKxHDE5ObAgEbAXObAlErUBBAUAFC4kFzmxEwMRErEPKzk5MDEANDYyFhQGIjc2NCczMjY1NCYjIRcGFBcHITI2NTQmIyEVIxEzFTMDITIWFRQGBx4BFRQGIyETAWAjLiMjLmQMDAckODgk/taJDAyJASokODgk/phUVGe7AbxHayMbGyNrR/5EuwFUMisrMikYEjASTygpT+8SMBLvTykoT1oBCFoBQ4BMKl8YGF8qTIABQwAAAwAyAAACoALaABYAHwAoAIwAsggAACuxJwTpshQDACuxGQTptCEfCBQNK7AAM7EhBOmwBTKyIR8KK7NAIQQJK7IfIQors0AfAQkrAbApL7AL1rARMrEkBemwHDKwJBCxBAErsAAysQMF6bEHFTIysSoBK7EkCxESsA45sAQRswYWGCgkFzkAsSEnERKwCzmwHxGwDjmwGRKwETkwMQE1MxEjNSMTISImNTQ2Ny4BNTQ2MyEDIzchIgYVFBYzFyMiBhUUFjMhAkxUVGe7/kRHayMbGyNrRwG8u2GK/tYkODgkoKAkODgkASoBl1r++Fr+vYBMKl8YGF8qTID+ve9PKShPVE8oKU8AAQAyAAADBALaABoAMQCyAQAAK7AHM7EABOmyDwMAK7AVM7EOBOkBsBsvsRwBKwCxDgARErMGCRQXJBc5MDElFSIuAS8BAyMBJy4CIzUyHgEfARMzARceAQMEJSs/G7/7bgEyxBIoHBgfLEQbv/tu/s7EGi9UVAYhIOT+1QFt6hUWBFQFIiDkASv+k+ofEAAAAQAyAAABQAEOAAsAQgCyBgAAK7AEM7QKBAAIBCuwADIBsAwvsAfWsAkytAMFAAgEK7ABMrENASuxAwcRErECCDk5ALEKBhESsQULOTkwMQEXBxcHJwcnNyc3FwEgIGhoIGdnIGhoIGcBDiBnZyBoaCBnZyBoAAD//wAyAAADOQLaECcH8gEbAAAQBgjXAAD//wAyAAAD7gLaECcIEAHQAAAQBgkcAAD//wAyAAAE8gLaECcIEgLUAAAQBgkdAAD//wAyAAAE8AN2ECcIEwLSAAAQBgkdAAD//wAyAAADkQLaECcIFAFzAAAQBgkdAAD//wAyAAADowN2ECcIFQFzAAAQBgkdAAD//wAyAAAE8ALaECcIFwLSAAAQBgkdAAD//wAyAAAFAAN2ECcIGALSAAAQBgkdAAD//wAyAAACagLaECYJLgAAEAcHrgHEAAD//wAyAAAC2ALaECYJLwAAEAcHrgIyAAD//wAyAAAC2AN2ECYJ/wAAEAcHrgB6Ac///wAyAAACiALaECYJMQAAEAcHrgHiAAD//wAyAAACiAN2ECcHrgHiAAAQJgkxAAAQBweuATwBz///ADIAAALYAtoQJgkzAAAQBweuAjIAAP//ADIAAALYA3YQJweuAjIAABAmCTMAABAHB64AagHPAAIAMgHlAV4CngADAAcAMQCwBC+0BQQAHwQrsAAvtAEEAB8EKwGwCC+xBAErsAAytAcFAAcEK7ACMrEJASsAMDETNSEVBTUhFTIBLP7UASwCYzs7fjs7AAABADIBiwFeAvgAEwByALAQL7ALM7QRBAAfBCuwCTKyEBEKK7NAEA4JK7AAL7AHM7QBBAAfBCuwBTKyAQAKK7NAAQMJKwGwFC+wDtaxAhIyMrQNBQAbBCuxBAgyMrINDgors0ANCwkrsAYysg4NCiuzQA4QCSuwADKxFQErADAxEzUzNTMVMxUjFTMVIxUjNSM1MzUyeDx4eHh4PHh4AmM7Wlo7QztaWjtDAAAABAAyAAACpAMgAAIABQAPABcAggCyAwAAK7IEAwArsgwDACuyEwIAK7QPBAATBCuwFy+0CQQAEwQrAbAYL7AD1rEABemwABCxBwErtBEFABEEK7ARELEVASu0DAUAEQQrsRkBK7EVERESsg4PCTk5OQCxDwMRErICAAU5OTmxBBMRErIGERQ5OTmwFxGyBxAVOTk5MDE3LQEDEQEANDYzMhYVFAYiJhQWMjY0JiKGAXv+hVQCcv6JJBoZJCQyBxMaExMajOHh/bIC2v6TAV0yJCQZGiRLGhMTGhMAAAQAMgAAAqQDIAAJABIAFQAYAIIAshcAACuyFgMAK7IFAwArsg0CACu0CAQAEwQrsBIvtAMEABMEKwGwGS+wAda0CwUAEQQrsAsQsRABK7QFBQARBCuwBRCxFQErsRcF6bEaASuxEAsRErIDAgg5OTkAsQgXERKyExUYOTk5sRYNERKyCwAPOTk5sBIRsgEKEDk5OTAxADQ2MhYVFAYjIiYUFjMyNjQmIhcNARMRAQEsJDQjJBkaBhIODRMTGvP+hQF7VP2OAsoyJCQZGiRLGhMTGhO14eECTv0mAW0AAAAABQAyAAACpAMgAAcACgANABcAIACpALIMAAArsgsDACuyEwMAK7IbAgArtBYEABMEK7AWELAHINYRtAMEABIEK7AQMrAgL7QRBAATBCsBsCEvsA/WtBkFABEEK7AJMrAZELEeASu0EwUAEQQrsBMQsQEBK7QFBQAaBCuwBRCxCgErsQwF6bEiASuxHhkRErIQERY5OTkAsRYMERKyCAoNOTk5sQsbERK0BQAOGR0kFzmwIBG0BAEPGB4kFzkwMQA0NjIWFAYiFw0BExEBEjQ2MhYVFAYjIiYUFjMyNjQmIgGEIjAiIjCq/oUBe1T9joIkNCMkGRoGEg4NExMaAs4wIiIwIl7h4QJO/SYBbQFdMiQkGRokSxoTExoTAAAFADIAAANAAyAABwAKAA0AFwAgALIAsgwAACuyCwMAK7ITAwArshsCACu0FgQAEwQrtAMHDBsNK7QDBAASBCuwIC+0EQQAEwQrAbAhL7AB1rQFBQAaBCuwBRCxDwErtBkFABEEK7AZELEeASu0EwUAEQQrsBMQsQoBK7EMBemxIgErsQ8FERKxCQ05ObEeGRESshEQFjk5OQCxBwwRErAKObADEbEJDTk5sBYSsAg5sQsbERKyDhkdOTk5sCARsg8YHjk5OTAxEjQ2MhYUBiIBDQETEQESNDYyFhUUBiMiJhQWMzI2NCYiMiIwIiIwApj+hQF7VP2O+iQ0IyQZGgYSDg0TExoBVTAiIjAiARvh4QJO/SYBbQFdMiQkGRokSxoTExoTAAAAAAMAMgAAAqQDIAAJABEAFwB1ALIUAAArshIDACuyBgMAK7INAgArtAkEABMEK7ARL7QDBAATBCsBsBgvsAHWtAsFABEEK7ALELEPASu0BgUAEQQrsRkBK7EPCxESsggJAzk5OQCxCRQRErETFzk5sRINERKyCwAOOTk5sBERsgEKDzk5OTAxADQ2MzIWFRQGIiYUFjI2NCYiBQkBNQkBAS0kGhkkJDIHExoTExr+1AJy/Y4Bz/4xAsoyJCQZGiRLGhMTGhMp/pP+k1oBEwETAAADADIAAAKkAyAACQASABgAdQCyEwAAK7IVAwArsgUDACuyDQIAK7QIBAATBCuwEi+0AwQAEwQrAbAZL7AB1rQLBQARBCuwCxCxEAErtAUFABEEK7EaASuxEAsRErIDAgg5OTkAsQgTERKxFBY5ObEVDRESsgsADzk5ObASEbIBChA5OTkwMQA0NjIWFRQGIyImFBYzMjY0JiIJAhUJAQEsJDQjJBkaBhIODRMTGgFH/Y4Ccv4xAc8CyjIkJBkaJEsaExMaE/z9AW0BbVr+7f7tAAAAAAQAMgAAAuADIAAJABEAGQAfAKoAshwAACuyGgMAK7IGAwArsg0CACu0CQQAEwQrtBUZHA0NK7QVBAASBCuwES+0AwQAEwQrAbAgL7AT1rQXBQAaBCuwFxCxAQErtAsFABEEK7ALELEPASu0BgUAEQQrsSEBK7EXExESsxocHR8kFzmxDwsRErIICQM5OTkAsRkcERKwHTmwFRGxGx45ObAJErAfObEaDRESsgsADjk5ObAREbIBCg85OTkwMQA0NjMyFhUUBiImFBYyNjQmIgA0NjIWFAYiEwkBNQkBAWkkGhkkJDIHExoTExr+mCIwIiIwGgJy/Y4Bz/4xAsoyJCQZGiRLGhMTGhP+UjAiIjAiAaf+k/6TWgETARMAAwAyAAACtgOAAAkAEgAiAHcAshQAACuxIQTpshkDACuxHATpsAgvtA0EABMEK7ASL7QDBAATBCsBsCMvsBfWsR8F6bAfELEBASu0CwUAEQQrsAsQsRABK7QFBQARBCuxJAErsRALERKyAwIIOTk5ALEcIRESsRcWOTmxEg0RErIBAAU5OTkwMQA0NjIWFRQGIyImFBYzMjY0JiIBISImEDYzIRUhIgYUFjMhATYkNCMkGRoGEg4NExMaAU/+v4W+voUBQf6/YouLYgFBAyoyJCQZGiRLGhMTGhP8ndYBLtZUpeilAAAAAAMAMgAAAh4DIAAJABEAKQCqALIZAAArsSIE6bIdAwArsgYDACuyDQIAK7QJBAATBCu0EikZDQ0rsRIE6bARL7QDBAATBCsBsCovsBzWtB8FADwEK7AfELEBASu0CwUAEQQrsAsQsQ8BK7QGBQARBCuwBhCxJQErtBYFADwEK7ErASuxAR8RErESKTk5sQ8LERK0CAkDGSIkFzkAsSkiERKwFjmxHQ0RErILAA45OTmwERGyAQoPOTk5MDESNDYzMhYVFAYiJhQWMjY0JiIDMzIWFRQGIyImNREzERQWMzI2NTQmKwHxJBoZJCQyBxMaExMaZoBigJFlYpRSXkZFX2BEbALKMiQkGRokSxoTExoT/pZ/UlB4k1MB9P4gOm5CNDVKAAAEADIAAALKAyAABwARABkAMQDXALIhAAArsSoE6bIlAwArsg4DACuyFQIAK7QRBAATBCu0GjEhFQ0rsRoE6bAaELMSGgMOK7QHBAASBCuwGS+0CwQAEwQrAbAyL7AB1rQFBQAaBCuwBRCxJAErtCcFADwEK7AnELEJASu0EwUAEQQrsBMQsRcBK7QOBQARBCuwDhCxLQErtB4FADwEK7EzASuxCScRErEaMTk5sRcTERK0EBELISokFzkAsQcqERKxHi05ObEaMRESswAEBQEkFzmxJRURErITCBY5OTmwGRGyCRIXOTk5MDESNDYyFhQGIgA0NjMyFhUUBiImFBYyNjQmIgMzMhYVFAYjIiY1ETMRFBYzMjY1NCYrATIiMCIiMAFJJBoZJCQyBxMaExMaZoBigJFlYpRSXkZFX2BEbAFVMCIiMCIBlzIkJBkaJEsaExMaE/6Wf1JQeJNTAfT+IDpuQjQ1SgADAB0AAAIeA4AACQARABcAfwCyEgAAK7EVBOmyEwMAK7AJL7QNBAATBCuwES+0AwQAEwQrAbAYL7AS1rQVBQA8BCuyFRIKK7NAFRcJK7MLFRIIK7QBBQARBCuwAS+0CwUAEQQrsw8VEggrtAYFABEEK7EZASuxDwsRErIICQM5OTkAsRENERKyAQAGOTk5MDESNDYzMhYVFAYiJhQWMjY0JiIDETMRIRUdJBoZJCQyBxMaExMaHFIBmgMqMiQkGRokSxoTExoT/J0C2v14UgAAAwAyAAAClgKPAAkAEwArAI4Ash8AACuxIATpsgcBACu0DQQAEwQrtBgnHw0NK7EYBOmwEi+0AwQAEwQrAbAsL7AU1rQrBQA8BCuwKxCxAAErtAoFABEEK7AKELEQASu0BQUAEQQrsAUQsSQBK7QbBQA8BCuxLQErsRAKERK0AwIHGCckFzkAsScgERKxGxQ5ObESDRESsgQFADk5OTAxATQ2MhYUBiMiJjcUFjMyNjQmIgYDNTQ2MzIWFRQGIyE1ITI2NTQmIyIGHQEBlCQ0IyQZGiQeEg4NExMaE7V/UlB4k1P+ggFqOm5CNDVKAlIZJCM0JCQaDhITGhMT/iuAYoCRZWKUUl5GRV9gRGwAAAADADIAAAKWAo8ACQATACsAjgCyIgAAK7EfBOmyBwEAK7QNBAATBCu0KBkiDQ0rsSgE6bASL7QDBAATBCsBsCwvsCXWtBwFADwEK7AcELEAASu0CgUAEQQrsAoQsRABK7QFBQARBCuwBRCxFQErtBQFADwEK7EtASuxEAoRErQDAgcZKCQXOQCxGR8RErEUJTk5sRINERKyBAUAOTk5MDETNDYyFhQGIyImNxQWMzI2NCYiBhMjNTQmIyIGFRQWMyEVISImNTQ2MzIWFcAkNCMkGRokHhIODRMTGhPtUko1NEJuOgFq/oJTk3hQUn8CUhkkIzQkJBoOEhMaExP+K2xEYF9FRl5SlGJlkYBiAAAAAAMAMgAAApYC2gAJABIAJACLALIfAAArsRwE6bIDAwArtBIEABMEK7QTFh8DDSuxEwTpsQ0DECDAL7QIBAATBCsBsCUvsCLWtBkFADwEK7IZIgors0AZFAkrsBkQsQEBK7QLBQARBCuwCxCxEAErtAUFABEEK7EmASuxEAsRErIDAgg5OTkAsRYcERKwIjmxEg0RErIBAAU5OTkwMRI0NjIWFRQGIyImFBYzMjY0JiIXMxUjIgYVFBYzIRUhIiY1NDbAJDQjJBkaBhIODRMTGgkyMjRCbjoBav6CU5N4AoQyJCQZGiRLGhMTGhPRUl9FRl5SlGJlkQAAAwAyAAABxgLaAAkAEQAgAH8AshoAACuyAwMAK7ASM7QRBAATBCu0FSAaAw0rsRUE6bENAxAgwC+0CQQAEwQrAbAhL7Aa1rEZBemwGRCxAQErtAsFABEEK7ALELEPASu0BgUAEQQrsAYQsSABK7EUBemxIgErsQ8LERKyCAkDOTk5ALERDRESsgEABjk5OTAxEjQ2MzIWFRQGIiYUFjI2NCYiNzMRIyIGHQEjNTQ+AjOVJBoZJCQyBxMaExMarFRoVYNUNVtvQQKEMiQkGRokSxoTExoTHf5rWEqjj0VoPB0AAAAAAwAyAAABxgLaAAkAEQAgAH8AshoAACuyAwMAK7ASM7QRBAATBCu0HhMaAw0rsR4E6bENAxAgwC+0CQQAEwQrAbAhL7Af1rETBemwExCxAQErtAsFABEEK7ALELEPASu0BgUAEQQrsAYQsRoBK7EZBemxIgErsQ8LERKyCAkDOTk5ALERDRESsgEABjk5OTAxEjQ2MzIWFRQGIiYUFjI2NCYiJxEyHgIdASM1NCYrARHpJBoZJCQyBxMaExMalEFvWzVUg1VoAoQyJCQZGiRLGhMTGhMd/rsdPGhFj6NKWAGVAAAAAwAyAAADDANVAAkAEwAzALkAsiAAACuxFwTpsjADACuxJwTpsgcDACu0DQQAEwQrsBIvtAMEABMEKwGwNC+wLNa0KwUAPAQrsCsQsSMBK7QUBQA8BCuzChQjCCu0AAUAEQQrsAAvtAoFABEEK7MQFCMIK7QFBQARBCuwFBCxGgErtB0FADwEK7E1ASuxACsRErEnMDk5sRAKERKyAwIHOTk5sRoFERKxFyA5OQCxJxcRErUbHCMrLDMkFzmxEg0RErIEBQA5OTkwMQE0NjIWFAYjIiY3FBYzMjY0JiIGExQWMzI2PQEzFRQGIyImNRE0JiMiBh0BIzU0NjMyFhUBYCQ0IyQZGiQeEg4NExMaE0pFNDJHUn5NTH9FNDJHUn5NTH8DGBkkIzQkJBoOEhMaExP91TttVDaRpU56jFABBDttVDaRpU56jFAAAAADADIAAAMMA1UACQATADMAtwCyKAAAK7ExBOmyGAMAK7EhBOmyBwMAK7QNBAATBCuwEi+0AwQAEwQrAbA0L7Ar1rQuBQA8BCuwLhCxFAErtCUFADwEK7MKJRQIK7QABQARBCuwAC+0CgUAEQQrsxAlFAgrtAUFABEEK7AlELEdASu0HAUAPAQrsTUBK7EALhESsSgxOTmxEAoRErIDAgc5OTmxHQURErEYITk5ALEhMRESsxUcJSwkFzmxEg0RErIEBQA5OTkwMQE0NjIWFAYjIiY3FBYzMjY0JiIGAxE0NjMyFh0BIzU0JiMiBhURFAYjIiY9ATMVFBYzMjYBYCQ0IyQZGiQeEg4NExMaEwh/TE1+UkcyNEV/TE1+UkcyNEUDGBkkIzQkJBoOEhMaExP91QEEUIx6TqWRNlRtO/78UIx6TqWRNlRtAAAAAAQAMgAAA7cDgAAHACcAMQA5AOEAshQAACuxCwTpsiQDACuxGwTptAcDFCQNK7QHBAASBCuwMS+0NQQAEwQrsDkvtCsEABMEKwGwOi+wAda0BQUAGgQrsAUQsSABK7QfBQA8BCuwHxCxFwErtAgFADwEK7MzCBcIK7QpBQARBCuwKS+0MwUAEQQrszcIFwgrtC4FABEEK7AIELEOASu0EQUAPAQrsTsBK7EpHxESsRskOTmxNzMRErIwMSs5OTmxDi4RErELFDk5ALEHCxESsQgXOTmwAxGzDxAfICQXObAbErEYJzk5sTk1ERKyKSguOTk5MDESNDYyFhQGIgUUFjMyNj0BMxUUBiMiJjURNCYjIgYdASM1NDYzMhYVAjQ2MzIWFRQGIiYUFjI2NCYiMiIwIiIwAh9FNDJHUn5NTH9FNDJHUn5NTH9oJBoZJCQyBxMaExMaAVUwIiIwIjk7bVQ2kaVOeoxQAQQ7bVQ2kaVOeoxQASwyJCQZGiRLGhMTGhMAAAADADIAAAHSAyAABwARABoAjQCyAAAAK7IDAwArsg0DACuyFQIAK7QQBAATBCu0AgYAFQ0rsQIE6bAaL7QLBAATBCsBsBsvsAnWtBMFABEEK7ATELEYASu0DQUAEQQrsA0QsQIBK7EFBemwBzKxHAErsRgTERKzCgsQBiQXObECDRESsAA5ALEDFRESsggTFzk5ObAaEbIJEhg5OTkwMSEBIREzESMTADQ2MhYVFAYjIiYUFjMyNjQmIgFr/scBTFT5+f7eJDQjJBkaBhIODRMTGgGXAUP+af69AsoyJCQZGiRLGhMTGhMAAwAyAAAB0gMgAAkAEQAZAI0AshMAACuyFgMAK7IGAwArsg0CACu0CQQAEwQrtBgVEw0NK7EYBOmwES+0AwQAEwQrAbAaL7AV1rATMrEYBemwGBCxAQErtAsFABEEK7ALELEPASu0BgUAEQQrsRsBK7EBGBESsBI5sQ8LERKzCAkDFCQXOQCxFg0RErILAA45OTmwERGyAQoPOTk5MDESNDYzMhYVFAYiJhQWMjY0JiIDIxMjETMRIdkkGhkkJDIHExoTExpxZ/n5VAFMAsoyJCQZGiRLGhMTGhP8/QFDAZf+vQAAAwAyAAAB+gOAABEAGwAjAJIAsgkAACuyEAMAK7EBBOm0CwYJEA0rsQsE6bAbL7QfBAATBCuwIy+0FQQAEwQrAbAkL7AO1rQEBQA8BCuwBBCxEwErtB0FABEEK7AdELEhASu0GAUAEQQrsBgQsQkBK7QIBQA8BCuwADKxJQErsSEdERKyGhsVOTk5ALEBBhESsQ0OOTmxIx8RErITEhg5OTkwMQEjIgYUFjsBESMRIyImNDY7ASQ0NjMyFhUUBiImFBYyNjQmIgH60kVfYETSUpRigIBi5v7fJBoZJCQyBxMaExMaAolFaEn+bQFBfaR4UDIkJBkaJEsaExMaEwAAAAIAMgAAAwYB+wAHAB8AhgCyDAAAK7EbBOmwFS+xEgTpsBIQsxISAw4rtAcEABIEKwGwIC+wD9a0GAUAPAQrswUYDwgrtAEFABoEK7ABL7QFBQAaBCuwGBCxHgErtAkFADwEK7EhASuxDwERErEDBjk5sR4YERKwDDkAsQcbERKyCA8YOTk5sRIVERKzAAQFASQXOTAxEjQ2MhYUBiIFFRQGIyImNTQ2MyEVISIGFRQWMzI2PQEyIjAiIjAB539SUHiTUwF+/pY6bkI0NUoBqTAiIjAiJYBigJFlYpRSXkZFX2BEbAAAAAACADIAAANKAfsABwAfAH0AsgwAACuxGwTpsBUvsRIE6bASELMSEgMOK7QHBAASBCsBsCAvsA/WtBgFADwEK7AYELEeASu0CQUAPAQrsAkQsQEBK7QFBQAaBCuxIQErsR4YERKwDDmxAQkRErETFDk5ALEHGxESsggPGDk5ObESFRESswAEBQEkFzkwMQA0NjIWFAYiBRUUBiMiJjU0NjMhFSEiBhUUFjMyNj0BAtYiMCIiMP7Tf1JQeJNTAX7+ljpuQjQ1SgGpMCIiMCIlgGKAkWVilFJeRkVfYERsAAAAAAMAMgAAAwYCiAAHAB8AJwCmALIMAAArsRsE6bIHAQArtAMEABIEK7QSFQwDDSuxEgTpsBIQsxISIw4rtCcEABIEKwGwKC+wD9a0GAUAPAQrsyUYDwgrtCEFABoEK7AhL7QlBQAaBCuwGBCxAQErtAUFABoEK7AFELEeCyu0CQUAPAQrsSkBK7EPIRESsSMmOTmxARgRErEMGzk5ALEnGxESsg8YCDk5ObESFRESsyAhJCUkFzkwMQA0NjIWFAYiFxUUBiMiJjU0NjMhFSEiBhUUFjMyNj0BJDQ2MhYUBiIBdSIwIiIwpH9SUHiTUwF+/pY6bkI0NUr+SSIwIiIwAjYwIiIwIrKAYoCRZWKUUl5GRV9gRGxHMCIiMCIAAwAyAAADSgKIAAcAHwAnAJ0AsgwAACuxGwTpsgcBACu0AwQAEgQrtBIVDAMNK7ESBOmwEhCzEhIjDiu0JwQAEgQrAbAoL7AP1rQYBQA8BCuwGBCxAQErtAUFABoEK7AFELEeCyu0CQUAPAQrsAkQsSEBK7QlBQAaBCuxKQErsQEYERKxDBs5ObEhCRESsRMUOTkAsScbERKyDxgIOTk5sRIVERKzICEkJSQXOTAxADQ2MhYUBiIXFRQGIyImNTQ2MyEVISIGFRQWMzI2PQEkNDYyFhQGIgEFIjAiIjCkf1JQeJNTAX7+ljpuQjQ1SgFdIjAiIjACNjAiIjAisoBigJFlYpRSXkZFX2BEbEcwIiIwIgAAAgAyAAAClgH7AAcAHwB3ALITAAArsRQE6bAbL7EMBOmwDBCzEgwDDiu0BwQAEgQrAbAgL7AB1rATMrQFBQAaBCuwBRCxCAErtB8FADwEK7AfELEYASu0DwUAPAQrsSEBK7EYHxESsAw5ALEHFBESswgPGB8kFzmxDBsRErMABAUBJBc5MDESNDYyFhQGIhc1NDYzMhYVFAYjITUhMjY1NCYjIgYdATIiMCIiMKl/UlB4k1P+ggFqOm5CNDVKAakwIiIwIv2AYoCRZWKUUl5GRV9gRGwAAAAAAgAyAAADBgH7AAcAHwB9ALITAAArsRQE6bAbL7EMBOmwDBCzEgwDDiu0BwQAEgQrAbAgL7AI1rQfBQA8BCuwHxCxGAErtA8FADwEK7MBDxgIK7QFBQAaBCuxIQErsRgfERKwDDmxBQ8RErECBzk5ALEHFBESswgPGB8kFzmxDBsRErMABAUBJBc5MDEANDYyFhQGIgU1NDYzMhYVFAYjITUhMjY1NCYjIgYdAQKSIjAiIjD+SX9SUHiTU/6CAWo6bkI0NUoBqTAiIjAi/YBigJFlYpRSXkZFX2BEbAAAAAADADIAAAKWAogABwAfACcAlwCyEwAAK7EUBOmyJwEAK7QjBAASBCu0DBsTIw0rsQwE6bAMELMSDAMOK7QHBAASBCsBsCgvsAHWsBMytAUFABoEK7AFELEIASu0HwUAPAQrsB8QsSELK7QlBQAaBCuwJRCxGAErtA8FADwEK7EpASuxGCURErEMGzk5ALEHFBESswgPGB8kFzmxDBsRErMABAUBJBc5MDESNDYyFhQGIhc1NDYzMhYVFAYjITUhMjY1NCYjIgYdARA0NjIWFAYiMiIwIiIwqX9SUHiTU/6CAWo6bkI0NUoiMCIiMAGpMCIiMCL9gGKAkWVilFJeRkVfYERsAawwIiIwIgAAAwAyAAADBgKIABcAHwAnAJ0AsgsAACuxDATpsicBACu0IwQAEgQrtAQTCyMNK7EEBOmwBBCzEgQbDiu0HwQAEgQrAbAoL7AA1rQXBQA8BCuwFxCxIQsrtCUFABoEK7AlELEQASu0BwUAPAQrsxkHEAgrtB0FABoEK7EpASuxECURErEEEzk5sR0HERKxGh85OQCxHwwRErMHABAXJBc5sQQTERKzGBkcHSQXOTAxNzU0NjMyFhUUBiMhNSEyNjU0JiMiBh0BADQ2MhYUBiIkNDYyFhQGIv1/UlB4k1P+ggFqOm5CNDVKAUMiMCIiMP6bIjAiIjCKgGKAkWVilFJeRkVfYERsAR8wIiIwIq8wIiIwIgAAAgAyAAADsgHaABIAGgByALIFAAArsRAE6bAKL7ELBOmwADKzEgoaDiu0FgQAEgQrAbAbL7AU1rQYBQAaBCuwGBCxCAErtA0FADwEK7IIDQors0AICgkrsA0QsRIBK7QCBQAxBCuxHAErsRINERKwBTkAsQsKERKzExQXGCQXOTAxATMVFAYjIiY9ASE1IRUUFjI2NSQ0NjIWFAYiA2FRelBSff6/AZNJaEX80SIwIiIwAcjmYoCAYpRS0kRgX0WSMCIiMCIAAAACADL//gOSAdoAEgAaAHIAsgwAACuwADOxCQTpsBAvsQUE6bMSEBoOK7QWBAASBCsBsBsvsBTWtBgFABoEK7AYELEBASu0AAUAMQQrsAAQsQwBK7QJBQA8BCuyCQwKK7NACQsJK7EcASuxDAARErAFOQCxBRARErMTFBcYJBc5MDEFIzU0NjMyFh0BIRUhNTQmIgYVJjQ2MhYUBiIBCVF6UFJ9AUH+bUloRdciMCIiMALmYoCAYpRS0kRgX0W4MCIiMCIAAwAy//4DkgKIAAcAGgAiAJQAshQAACuwCDOxEQTpsiIBACu0HgQAEgQrtA0YFB4NK7ENBOmzEhgHDiu0AwQAEgQrAbAjL7AB1rQFBQAaBCuwBRCxCQErtAgFADEEK7AIELEcASu0IAUAGgQrsCAQsRQBK7QRBQA8BCuyERQKK7NAERMJK7EkASuxIBwRErIXGA05OTkAsQ0YERKzAQQFACQXOTAxEjQ2MhYUBiITIzU0NjMyFh0BIRUhNTQmIgYVEjQ2MhYUBiIyIjAiIjC1UXpQUn0BQf5tSWhFPiIwIiIwAYgwIiIwIv6Y5mKAgGKUUtJEYF9FAWYwIiIwIgAAAAIAMgAAAqQC2gASABoAdQCyCwAAK7IBAwArsQAE6bQJDAsBDSuxCQTpsAkQsxIJGg4rtBYEABIEKwGwGy+wFNa0GAUAGgQrsBgQsQsBK7AAMrQKBQA8BCuwChCxEAErtAUFADwEK7EcASsAsQwJERKzExQXGCQXObEAFhESsQUPOTkwMRM1MzIWFRQGKwERIxEzMjY0JiMANDYyFhQGItzmYoCAYpRS0kRgX0X+hCIwIiIwAolRelBSff6/AZNJaEX+zDAiIjAiAAAAAAMAMgAAAqQDdgAHABoAIgCZALITAAArsgkDACuxCATptBEUEwkNK7ERBOmwERCzEhEHDiu0AwQAEgQrsCIvtB4EABIEKwGwIy+wAda0BQUAGgQrsAUQsRMBK7AIMrQSBQA8BCuzGhMcDiu0IAUAGgQrsBIQsRgBK7QNBQA8BCuxJAErsRITERKzHR4hIiQXOQCxFBERErMBBAUAJBc5sQgDERKxDRc5OTAxEjQ2MhYUBiITNTMyFhUUBisBESMRMzI2NCYjJjQ2MhYUBiIyIjAiIjCI5mKAgGKUUtJEYF9F4yIwIiIwAVUwIiIwIgFWUXpQUn3+vwGTSWhFmzAiIjAiAAAAAgAyAAACfALaABEAGQB3ALIJAAArshADACuxAQTptAsGCRANK7ELBOmwCxCzEgsZDiu0FQQAEgQrAbAaL7AT1rQXBQAaBCuwFxCxDgErtAQFADwEK7AEELEJASu0CAUAPAQrsAAysRsBKwCxBgsRErMSExYXJBc5sQEVERKyBA0OOTk5MDEBIyIGFBY7AREjESMiJjQ2OwEANDYyFhQGIgJ80kVfYETSUpRigIBi5v22IjAiIjACiUVoSf5tAUF9pHj+ezAiIjAiAAAAAQAyAW0B2wLdAAUAEQCyBAMAKwGwBi+xBwErADAxAQsBIxsBAZ6Xlj/V1AFtAQT+/AFw/pAAAAABADIBbQGSAtoADwA6ALIMAwArtAQEAB8EKwGwEC+wCNa0BwUAEQQrsAcQsQABK7QPBQARBCuxEQErsQAHERKxCww5OQAwMQE1NCYiBh0BIzU0NjIWHQEBXEhkSDZnkmcBbb0ySEgyvb1JZ2dJvQAAAQAyAWwBNwLaABUAVQCyEAMAK7QHBAAfBCuwAC+0AQQAHwQrAbAWL7AM1rQLBQARBCuwCxCxBQErtBMFABEEK7IFEwors0AFAAkrsRcBK7EFCxESsBA5ALEHARESsBM5MDETNTMyNjQmIyIGHQEjETQ2MzIWFRQjgisjLy8jICM4SDM4UooB+jgeNB4jHPcBDyg3OjZwAAABADIBbAE3AtoADwBDALINAwArtAQEAB8EK7IEDQors0AEAAkrAbAQL7AJ1rQIBQARBCuwCBCxAQErtAAFABEEK7ERASuxAQgRErANOQAwMQEjNCYjIgYdASMRNDYzMhYBNzgvIyAjOEgzOFICahoeIxz3AQ8oNzoAAAAAAQAyAW0BKALaAAUAOACyAAMAK7QDBAAfBCuyAwAKK7NAAwUJKwGwBi+wBda0BAUAEQQrsgQFCiuzQAQCCSuxBwErADAxEzMVIxEjMva7OwLaOv7NAAAAAAEAMgFsAaACcQAVAFMAsAMvtBIEAB8EK7ISAwors0ASFQkrsAwvtAkEAB8EKwGwFi+wBta0DwUAEQQrsA8QsRQBK7QBBQARBCuxFwErsRQPERKwAzkAsQwSERKwBjkwMQEVFCMiJjU0NjMhFSMiBhUUFjI2PQEBEnA2OjcoAQ/3HCMeNB4CISuKUjgzSDgjICMvLyMrAAAAAQAyAW0BBALaAAwAPgCyBwMAK7AML7QDBAATBCuyDAMKK7NADAEJKwGwDS+wAda0AAUAEQQrsAAQsQYBK7QJBQARBCuxDgErADAxEyM1MzI2PQEzFRQGI2g2QiY0NlZGAW27NzBLPlZQAAAAAQAyAW0BtAJmACgAoACwGi+wCTO0GQQAEwQrsCYysA8vsAIztB8EABMEK7ADMgGwKS+wHNa0EgUAEQQrshIcCiuzQBIaCSuwEhCxAAErtAYFABEEK7IABgors0AAAwkrsSoBK7A2GrrBXfLeABUrCg6wDRCwDMCxIhb5sCPAALMMDSIjLi4uLgGzDA0iIy4uLi6wQBoBsQASERKxCR85OQCxDxkRErEGHDk5MDEBNCc1MhYVFAYjIiYvASYjIgYVFB4EMxUmNTQ2MzIWHwEeATMyNgGCODA6PCosMgoNCi4YJQgKFAsYA35FLSU5CQ0HHBUWHAHmTAIyQjw7QCkwPjAnKREZDggCAzIEcD5HLSs/HhIjAAAAAAMAMgFtAg0C3QACAAUADQA/ALIBAwArsAAvtAUEAB8EK7ANL7QJBAASBCsBsA4vsAfWtAsFABoEK7EPASuxCwcRErAAOQCxCQ0RErAEOTAxGwIvAQcmNDYyFhQGImTV1F13d5AiMCIiMAFtAXD+kDbOzokwIiIwIgAAAAADADIBbQINAt0AAgAFAA0APwCyAQMAK7AAL7QFBAAfBCuwDS+0CQQAEgQrAbAOL7AH1rQLBQAaBCuxDwErsQsHERKwAjkAsQkNERKwBDkwMRsCLwEHJDQ2MhYUBiIy1dRdd3cBCSIwIiIwAW0BcP6QNs7OiTAiIjAiAAAAAgAyAl8ArQLaAAkAEgBSALIDAwArtBIEABMEK7AIL7QNBAATBCsBsBMvsAHWtAsFABEEK7ALELEQASu0BQUAEQQrsRQBK7EQCxESsgMCCDk5OQCxEg0RErIBAAU5OTkwMRI0NjIWFRQGIyImFBYzMjY0JiIyJDQjJBkaBhIODRMTGgKEMiQkGRokSxoTExoTAAAAAAEAMgJmAKYC2gAHADUAsgMDACu0BwQAEgQrsgMDACu0BwQAEgQrAbAIL7AB1rQFBQAaBCu0BQUAGgQrsQkBKwAwMRI0NjIWFAYiMiIwIiIwAogwIiIwIgACADIAAAOmAdoABwAaAHIAsg0AACuxGATpsBIvsRME6bAIMrMSEgcOK7QDBAASBCsBsBsvsBDWtBUFADwEK7IQFQors0AQEgkrsBUQsRoBK7QKBQAxBCuwChCxAQErtAUFABoEK7EcASuxGhURErANOQCxExIRErMBBAUAJBc5MDEANDYyFhQGIiczFRQGIyImPQEhNSEVFBYyNjUDMiIwIiIwmVF6UFJ9/r8Bk0loRQGIMCIiMCJi5mKAgGKUUtJEYF9FAAAAAAIAIQAAAfoDdgAHABkAbgCyGQAAK7EIBOmyEAMAK7QSDxkQDSuxEgTpsAcvtAMEABIEKwGwGi+wD9awCDK0EgUAPAQrsxoPAQ4rtAUFABoEK7ASELEMASu0FgUAPAQrsRsBK7ESDxESswMGBwIkFzkAsQ8IERKxFRY5OTAxEjQ2MhYUBiIDMzI2NCYrAREzETMyFhQGKwEhIjAiIjAR0kVfYETSUpRigIBi5gMkMCIiMCL9T0VoSQGT/r99pHgAAAIAMgAAAgsDdgAHABoAbACyCgAAK7EaBOmyEgMAK7QQFQoSDSuxEATpsAcvtAMEABIEKwGwGy+wDda0GAUAPAQrsBgQsREBK7QUBQA8BCuwCDKzGhEBDiu0BQUAGgQrsRwBK7EUERESswMGBwIkFzkAsRUaERKwDTkwMQA0NjIWFAYiExUjIiY1NDY7AREzESMiBhQWMwGXIjAiIjBB5mKAgGKUUtJEYF9FAyQwIiIwIv1PUXpQUn0BQf5tSWhFAAMAMgAAA1gC2gAXAB8AJwCaALIEAAArsRQE6bIKAwArsAAzsR8E6bQnIwQKDSu0JwQAEgQrtBsOBAoNK7EbBOkBsCgvsAbWsREF6bAYMrARELEdASuxDAXpsAwQsRYBK7EBBemwARCxIQErtCUFABoEK7EpASuxHRERErQJCgQOEyQXObEWDBESsQMUOTkAsQ4nERKxISQ5ObAjEbAQObEfGxESsQwLOTkwMQERFAYiJjURNDYyFhQGIyInFRQWMjY1EQQUFjI2NCYiADQ2MhYUBiICtMX4xWSMZGRGLSmVsJX+JjNGMzNGAisiMCIiMALa/kp2rq52AQxGZGSMZBd5U319UwG2h0YzM0Yz/s8wIiIwIgAAAAADADIAAAMoAtoAFwAfACcAnQCyAQAAK7EWBOmyBgMAK7ERBOmwGDK0JyMBBg0rtCcEABIEK7QdDAEGDSuxHQTpAbAoL7AE1rEUBemwFBCxDgErsRsF6bAbELEfASuxCgXpsAAysAoQsSELK7QlBQAaBCuxKQErsRsOERKwEDmwHxGxDAs5OQCxJxYRErEUAzk5sAwRsSEkOTmxHSMRErATObAREbMJCgQOJBc5MDEpASImEDY7ATIWFAYiJjU0NyMiBhQWMyECIgYUFjI2NBY0NjIWFAYiArT+onmrq3m0RmRkjGQXIVN9fVMBXodGMzNGM1QiMCIiMNQBMtRkjGRkRi0psNKwAjIzRjMzRv4wIiIwIgADADIAAANYAtoAAwATABsAfACyCAAAK7EQBOmyCwMAK7EABDMzsgsDACu0GxcICw0rtBsEABIEKwGwHC+wCtaxDQXpsA0QsQMBK7QCBQARBCuwAhCxEgErsQUF6bAFELEVASu0GQUAGgQrsR0BK7EDDRESsQgPOTmxEgIRErEHEDk5ALELFxESsAI5MDEBMxEjAREUBiImNREzERQWMjY1ERI0NjIWFAYiAVY7OwFexfjFVJWwlYQiMCIiMALZ/tQBLf5Kdq6udgG2/kpTfX1TAbb+ezAiIjAiAAAAAwAyAAACtgN2AAcACwAbAGkAshMAACuxFATpsgwDACuxGwTptAgJEwwNK7QIBAAfBCuwBy+0AwQAEgQrAbAcL7AB1rQFBQAaBCuwBRCxGAErsRAF6bEdASuxBQERErEKCzk5ALEIFBESsRAXOTmxGwkRErEPGDk5MDEANDYyFhQGIgE1IRUBITIWEAYjITUhMjY0JiMhAToiMCIiMP7WASz+1AFBhb6+hf6/AUFii4ti/r8DJDAiIjAi/k46OgGK1v7S1lSl6KUAAAAAAwAyAAACtgN2AAMAEwAbAGkAsgUAACuxEgTpsgoDACuxDQTptAABBQoNK7QABAAfBCuwGy+0FwQAEgQrAbAcL7AI1rEQBemwEBCxFQErtBkFABoEK7EdASuxGRURErEBADk5ALEAEhESsQcQOTmxDQERErEIDzk5MDEBNSEVESEiJhA2MyEVISIGFBYzIQA0NjIWFAYiAYoBLP6/hb6+hQFB/r9ii4tiAUH+hCIwIiIwAVA6Ov6w1gEu1lSl6KUC0DAiIjAiAAACADIAAALEAtoAGAAgAIQAsgIAACuwDTOyCQMAK7ESBOm0HCACCQ0rtBwEABIEK7ADINYRsRgE6QGwIS+wBtawAjK0FQUAPAQrsBUQsQ4BK7QNBQA8BCuwDRCxGgErtB4FABoEK7EiASuxDhURErMBAAkDJBc5ALEYIBESsRkeOTmwHBGxGh05ObASErEGFTk5MDEJASMTIiY1NDYzMhYVESMRNCYjIgYVFBYzBDQ2MhYUBiIBsf7lZOFif5FlYpRSXkZFX2BEASgiMCIiMAGT/m0BQX9SUHiTU/4MAeA6bkI0NUoLMCIiMCIAAAIAMgAAAh4DTgAHACAAfQCyGAAAK7EPBOmyHwMAK7ATM7IHAwArtAMEABIEK7QJHhgDDSuxCQTpAbAhL7Ab1rAfMrQMBQA8BCuwDBCxAQErtAUFABoEK7AFELESASu0FQUAPAQrsSIBK7EBDBESsCA5sAURsg8YHjk5ObASErAIOQCxCQ8RErAbOTAxADQ2MhYUBiITIyIGFRQWMzI2NREzERQGIyImNTQ2MwMzAQIiMCIiMI2JRGBfRUZeUpRiZZF/YuFkAvwwIiIwIv5tSjU0Qm46AeD+DFOTeFBSfwFBAAAAAAIAMgAAAvYC2gAnAC8ApQCyJwAAK7IiAwArsQME6bQcCSciDSuxHATptCsvJyINK7QrBAASBCu0FA4nIg0rsRQE6bIOFAors0AOEgkrAbAwL7Af1rEGBemwBhCxEgErsREF6bARELELASuxFwXpsBcQsScBK7EmBemwJhCxKQErtC0FABoEK7ExASuxERIRErEJHDk5sAsRsgMUIjk5OQCxKy8RErELFzk5sA4RsQYfOTkwMQE0JiMiBhUUFjMyNTQmIyIGFSM0MzIWFRQOAiMiJjU0NjMyFhURIxI0NjIWFAYiAgBvTlJrPDVvGQ4RDlRzMkkVK0wxVnWec3ChVIIiMCIiMAHMTm9US0xLeRIcHCaTUywkRD0lg2Vtg59v/jQBiDAiIjAiAAAAAAIAMgAAAmUDdgAnAC8ApwCyBgAAK7ElBOmyAQMAK7QUGgYBDSuxFATpshoUCiuzQBoWCSu0DB8GAQ0rsQwE6bAvL7QrBAASBCsBsDAvsAnWsSIF6bAiELEWASuxFwXpsBcQsR0BK7ERBemwERCxAAErsQMF6bMaACkOK7QtBQAaBCuxMQErsRcWERKxDB85ObAdEbIUBiU5OTmxAwARErMqKy4vJBc5ALEfGhESsgkRIjk5OTAxAREzERQGIyImNTQ2MzIeAhUUBiMiNTMUFjMyNjU0IyIGFRQWMzI2AjQ2MhYUBiICAFShcHOedVYxTCsVSTJzVA4RDhlvNTxrUk5vDyIwIiIwAQ4BzP40b5+DbWWDJT1EJCxTkyYcHBJ5S0xLVG8CZDAiIjAiAAIAMgAAAkQDTgAUABwAmQCyDAAAK7IJAwArsQ0E6bIcAwArtBgEABIEK7QTBAwYDSuxEwTpsgQTCiuzQAQACSsBsB0vsADWsQEF6bABELEGASuxEAXpsBAQsBog1hG0FgUAGgQrsBYvtBoFABoEK7AQELEMASuxCwXpsR4BK7EWARESsQMTOTmwBhGzBBIXHCQXObAaErEYGzk5ALENBBESsQYQOTkwMRMzFBYyNjU0NjsBESMRIgYVFAYiJhI0NjIWFAYiMlQ2TDZdVVRULTFnkmfQIjAiIjAB0SY2NiZxmP0mAoZvRklnZwF0MCIiMCIAAAACADIAAANYAtoAHgAmAHoAsgcAACuwAzOxEATpsBkysgsDACuxFB0zM7QmIgcLDSu0JgQAEgQrAbAnL7AK1rENBemwDRCxEwErsRYF6bAWELEcASuxAAXpsAAQsSABK7QkBQAaBCuxKAErsRMNERKwBzmwFhGwBTmwHBKwAzkAsRAHERKwBTkwMSUUBiMiJwYjIiY1ETMRFBYzMjY1ETMRFBYzMjY1ETMSNDYyFhQGIgKgaElPNzdPSWhUNyYlN1Q3JSY3VEQiMCIiMLJKaD4+aEoCKP3YJjY2JgIo/dgmNjYmAij+ezAiIjAiAAIAMgAAAqADdgAgACgAagCyDQAAK7EOBOmyIAMAK7EfBOm0FhcNIA0rsRYE6bAoL7QkBAASBCsBsCkvsCLWtCYFABoEK7AmELESASuwGzKxCQXpsAMysSoBK7EJEhESsAY5ALEWDhESsAk5sBcRsAY5sB8SsAM5MDEBMhYVFAYHHgEVFAYjITUhMjY1NCYjITUhMjY1NCYjITUkNDYyFhQGIgHuR2sjGxsja0f+RAG8JDg4JP5EAbwkODgk/kQBCCIwIiIwAtqATCpfGBhfKkyAVE8pKE9UTygpT1RKMCIiMCIAAAIAMgAAAqADdgAgACgAagCyAAAAK7EeBOmyDAMAK7EPBOm0GBUADA0rsRgE6bAoL7QkBAASBCsBsCkvsAPWsAkysRsF6bASMrAbELEiASu0JgUAGgQrsSoBK7EbAxESsAY5ALEYHhESsAM5sBURsAY5sA8SsAk5MDEzIiY1NDY3LgE1NDYzIRUhIgYVFBYzIRUhIgYVFBYzIRUANDYyFhQGIuRHayMbGyNrRwG8/kQkODgkAbz+RCQ4OCQBvP6aIjAiIjCATCpfGBhfKkyAVE8pKE9UTygpT1QDJDAiIjAiAAAAAAIAMgAAA1gC2gAgACgAiQCyAAAAK7EeBOmyDAMAK7EPBOm0GBUADA0rsRgE6bAYELMSGCgOK7QkBAASBCsBsCkvsAPWsAkysRsF6bASMrAbELEiASu0JgUAGgQrsSoBK7EbAxESsAY5sCIRsw0WHyAkFzkAsSgeERKxGwM5ObEVGBEStAYhIiUmJBc5sQ8kERKxCRI5OTAxMyImNTQ2Ny4BNTQ2MyEVISIGFRQWMyEVISIGFRQWMyEVEjQ2MhYUBiLkR2sjGxsja0cBvP5EJDg4JAG8/kQkODgkAbxEIjAiIjCATCpfGBhfKkyAVE8pKE9UTygpT1QBVTAiIjAiAAACADIAAAJVA3YABwAuAKQAsiQAACuxEQTpsiwDACuxKwTptBceJCwNK7EXBOmyFx4KK7NAFxsJK7AHL7QDBAASBCsBsC8vsCfWsCsysQ4F6bAOELEBASu0BQUAGgQrsxoFAQgrsRsF6bAbL7EaBemwBRCxFAErsSEF6bAtMrEwASuxGhsRErUCBgcDESQkFzmxFAURErIXHio5OTkAsRcRERKyDiEnOTk5sSseERKwLjkwMQA0NjIWFAYiAw4EFRQWMzI2NTQmIyIGFSM0NjMyFhUUBiMiJjU0PwEhNSEVAQkiMCIiMC8iLRgNAnVPR3AxHiIgVFVBPWaZcnWjoPL+bgIjAyQwIiIwIv6vFCghLR8cN2FaMCo2JjJRW2NRUoyQWrRcjFRhAAIAMgAAA6YCIwAmAC4AmACyCAAAK7ADM7EhBOmwFC+xFQTpsBsvsQ4E6bABMrMqDhsIK7QuBAASBCsBsC8vsAvWsR4F6bAeELEYASuxEQXpshgRCiuzQBgUCSuwERCxBAErsQMF6bADELEoASu0LAUAGgQrsTABK7EYHhESsggOITk5ObEEERESsAE5ALEVFBESsQseOTmxGy4RErQRGAUoKyQXOTAxJRMzESMRBwYjIiY1NDYzMhYVFAYjNTI2NTQmIyIGFRQWMzI+AyQ0NjIWFAYiAePIYVSMXLRakIxSUWNbUTImNiowWmE3HB8tISgBYyIwIiIwygFZ/d0BkvKgo3VymWY9QVVUICIeMXBHT3UCDRgt4DAiIjAiAAAAAAEAMgFtAOYC2gAJAEoAsggDACu0BwQAEwQrsAMvtAQEABMEK7AAMgGwCi+wBda0AAUAEQQrsgAFCiuzQAACCSuwABC0BwUAIwQrsAcvsAMzsQsBKwAwMRMzFSM1MxEjNTOlQbRBQXMBnzIyAQkyAAABADIBbAENAnYADgAwALACL7QMBAAfBCuwCDIBsA8vsAfWtAYFABEEK7AJMrEQASsAsQwCERKxCg45OTAxEyYjIgYdASMRMxU2MzIX5xcjICM4OBwnOCgCLw8jHJMBCA0PHQAAAQAyAW0BMQJ0ABwAfACwEi+0EwQAEwQrsBsvtAsEABMEK7AGL7QDBAATBCsBsB0vsAHWtAkFABEEK7IJAQors0AJBQkrsAkQsRcBK7QPBQARBCuyFw8KK7NAFxMJK7EeASuxFwkRErEMGzk5ALETEhESsA85sQsbERKxAA45ObEDBhESsAE5MDESNDY7ARUjIgYUFjsBMhYUBisBNTMyNjU0JisBIjIsH6ioCw4PCm0dKiodrq4JDAwJbR8CB0IrMhESFC9CLTITCQoUAAAA//8ABQAAAeMCDRAGFNgAAP//AAoAAAK1Ag0QBhTyAAD//wAm/+sDUQIdEA8AqANvAgbAAP//ACH/6QHwAhwQBhTaAAD//wA2AAAB3AINEAYU2wAA//8ACgAAAeICDRAGFPYAAP//ADYAAAGuAg0QBhTcAAD//wAe/+kBxwIbEAYB/wAA//8ASP8zAJwCDBAPAEwA3gIMwAD//wAU/+kBRwINEAYU4QAA//8ANgAAAeYCDRAGFOIAAP//AAUAAAGSAg0QBhT3AAD//wA2AAACMAINEAYU5AAA//8AIf/pAigCHBAGFOYAAP//ADYAAAG2Ag0QBhTnAAD//wAO//8B2gIMEA8CJAIaAgzAAP//ABcAAAHCAg0QDxTpAfgCDcAA//8AFAAAAbACDRAGFOsAAP//ADb/6QHJAg0QBhTsAAD//wAFAAAB0wINEAYU7QAA//8ABQAAAp8CDRAGFO4AAP//AB4AAAGuAg0QBhTxAAD//wAFAXoBZALzEA8B9f/4AYQq4f//AAUBaQE6AvAQDwH4//4Bhirh//8ADwF1AU0DdxAPALL/+wGFKuH//wAJAXUBJgLvEA8B///1AYUq4f//AAwBhwCsA3AQDwILAAIBhyrh//8ALQF3AJ8C5xAPAgwAAQGHKuH//wAsAYYAYgLmEA8U4AAAAYYq4f//ACIBhgD9AuYQDxTj//4Bhirh//8AJgDzAfYC8BAPAhT//gGGKuH//wAgAQEB8ALnEA8CE//4AYcq4f//AA4A8wFiAvAQDwIVAAgBhirh//8AKQDzAX0C8BAPAhYAAQGGKuH//wAmAYYBRQLmEA8CF//+AYYq4f//AA8BdQFNAu8QDwIY//sBhSrh//8ADgEOAbsDchAPAhv//gGUKuH//wAPAXYBfwLzEA8CLf/7AYYq4f//ACcBdwE2AucQDwpgAAMBhyrh//8AKAF2AUkC5hAPAi4AAAGGKuH//wAKAPQBYwLlEA8CM//2AYYq4f//AAoBRQE3AuYQDwI0//YBhirh//8ADQEmAUsC5hAPAjUAAAGGKuH//wAPAX0BOgNwEA8DS//7AYYq4f//AA//AwKLAtkQIwJ9AKj80hACACQAAP//AB7/AwILAhsQIwJ9AGz80hACAEQAAP//AFAAAAJwA3MQIwJ8AKsApxACACUAAP//ADz/6QIRAtkQIwJ8AI0ADRACAEUAAP//AFD/XAJwAtkQIwJ8AI78+BACACUAAP//ADz/RQIRAtkQIwJ8AID84RACAEUAAP//AFD/fgJwAtkQIwBxAIX9BxACACUAAP//ADz/ZwIRAtkQIwBxAIL88BACAEUAAP//ACj/KgKdA4QQJxhZAUoAABACAIkAAP//AB7/KgHcAusQIwB2AI4ABxACAKkAAP//AFAAAAKSA3MQIwJ8AL8ApxACACcAAP//AB7/6QHzAtkQIgJ8Xg0QAgBHAAAAAP//AFD/XAKSAtkQIwJ8AIv8+BACACcAAP//AB7/RQHzAtkQIwJ8AFf84RACAEcAAP//AFD/fgKSAtkQIwBxAJn9BxACACcAAP//AB7/ZwHzAtkQIwBxAFn88BACAEcAAAACAFn/MQKbAtkAIgArAIoAsg4AACuwFjOxIwTpshADACuxKwTpsCAvtAUEABMEK7AKL7QaBAATBCsBsCwvsA/WsSMF6bAjELEIASu0HQUAJgQrsB0QsScBK7EUBemxLQErsSMPERKxACI5ObAIEbYCDQ4XGBogJBc5ALEFIBESsCI5sAoRswAMDR0kFzmxKyMRErETFDk5MDEXHgMzMjY1NCMiByc3IxEhMhYQBisBBzYzMhYVFAYjIicTMzI2NTQmKwGpCSERGg0XHy4PEAwntgEZi56fij0UDQ8mKUI5L04irGxwcGyshQQQBwYaEyUIB1UC2cL+rMMxAiMgKzIiAP+QiouQAAACABr/GgHvAtkAKQA1AKMAsgIAACuyBgAAK7IgAAArsikDACuyJgEAK7EqBOmwDy+0FwQAEwQrsBwvtAkEABMEKwGwNi+wI9axLQXpsC0QsRoBK7QMBQAmBCuwDBCxMwErsCgytAEFADwEK7ABELQCBQAbBCuwAi+xNwErsRotERJACgYJDxEHHyAmKjAkFzkAsRcPERKwETmwHBGzDBIeHyQXObEqAhESsgMoMDk5OTAxAREjNQ4BDwE2MzIWFRQGIyInNx4DMzI2NTQjIgcnNy4BNTQ2MzIXEQMiBhUUFjMyNjU0JgHvSh5BKxQNDyYpQjkvThUJIREaDRcfLg8QDCdndHtmbDWTRFRURUJQUALZ/SdFLCoGMQIjICsyIigEEAcGGhMlCAdWB5h+fZdRAQ/+9HBbXG9uW15vAAAA//8AUP8uApIC2RAjAmkAjPzfEAIAJwAA//8AHv8XAfMC2RAjAmkAWvzIEAIARwAA//8AUAAAAlsD1BAnGFgAvgBQECMAcQC8AIMQAgAoAAD//wAe/+kB9wNcECIAcXLiEiIASAAAEAIAQ154//8AUAAAAlsD1BAnGFkBDgBQECMAcQC8AIMQAgAoAAD//wAe/+kB9wNYECIAcXLiEiIASAAAEAMAdgCFAHQAAP//AFD/LgJbAtkQIwJpALz83xACACgAAP//AB7/FwH3AhsQIwJpAHL8yBACAEgAAP//AFD/XAJbAtkQIwJ/AL789xACACgAAP//AB7/RQH3AhsQIwJ/AHT84BACAEgAAP//AFD/MQJbA6gQIwJ7ALEAzBACAeQAAP//AB7/GgH3At4QIgJ7cgIQAgHlAAAAAP//AFAAAAI5A3MQIwJ8AKgApxACACkAAP//ABQAAAEEA3MQIwJ8AA4ApxACAEkAAP//ACj/6QLBA2cQIwBxAOUAqhACACoAAP//AB7/JgHqAp0QIgBxcuAQAgBKAAAAAP//AFAAAAKBA3EQIwJ8AMQApRACACsAAP//ADwAAAHcAtkQIwJ8AIsADRACAEsAAP//AFD/XAKBAtkQIwJ8AMT8+BACACsAAP//ADz/XAHcAtkQIwJ8AG/8+BACAEsAAP//AFAAAAKBA28QIwBqAMgAoxACACsAAP//ADwAAAHcA14QIwBqAIYAkhICAEsAAAAB//H/MQKEAtkAJgCFALIPAAArsRYaMzOyEAMAK7AUM7AkL7QFBAATBCuwCi+0HgQAEwQrtBIZDxANK7ESBOkBsCcvsA/WsRoF6bARMrMIGg8IK7QhBQAmBCuwGhCxFwErsBMysRYF6bEoASuxCA8RErYFCg4bHB4kJBc5ALEFJBESsCY5sAoRswAMDSEkFzkwMRceAzMyNjU0IyIHJzcjETMRIREzESMRIREjBzYzMhYVFAYjIicGCSERGg0XHy4PEAwnGV0Bd11d/okeFA0PJilCOS9OhQQQBwYaEyUIB1UC2f7FATv9JwFM/rQxAiMgKzIiAAAAAAH/3/8xAeYC2QAuAJgAsiMAACuxBy0zM7IkAwArsikBACu0AwQAQwQrsBEvtBkEABMEK7AeL7QLBAATBCsBsC8vsCPWtAcFADwEK7AlMrMcByMIK7QOBQAmBCuwBxCxLgErtC0FADwEK7EwASuxHCMRErYICxEZCR4iJBc5sS4OERKxAyk5OQCxGRERErATObAeEbMOFCAhJBc5sQMjERKwJjkwMQE0JiMiBhURIwc2MzIWFRQGIyInNx4DMzI2NTQjIgcnNyMRMxE+ATMyFhURIwGTQylAThkUDQ8mKUI5L04VCSERGg0XHy4PEAwnFFMlSzhMWVMBazcwYVD+3zECIyArMiIoBBAHBhoTJQgHVQLZ/uswJ01C/nT//wBQ/z0CgQLZECMCewDG/OgQAgArAAD//wA8/z0B3ALZECMCewBw/OgQAgBLAAD////2/1wBMALZECMCf//x/PcQAgAsAAD////j/1wBHQLZECMCf//e/PcQAgBMFAD//wAFAAABSAPoECYYWVpkECMAav/sAIwQAgAsAAAAAP////QAAAEgA4QQJhhZMgAQJgDzFAAQAgBq2/j//wBQAAACkwOEECcYWQEOAAAQAgAuAAD//wA8AAAB+AOEECcYWQC0AAAQAgBOAAD//wBQ/1wCkwLZECMCfADK/PgQAgAuAAD//wA8/1wB+ALZECMCfABx/PgQAgBOAAD//wBQ/34CkwLZECMAcQDC/QcQAgAuAAD//wA8/34B+ALZECMAcQBz/QcQAgBOAAD//wBQ/1wCFQLZECMCfACM/PgQAgAvAAD//wA6/1wAogLZECMCfP/H/PgQAgBPAAD//wBQ/1wCFQNnECMAcQCSAKoQAgqwAAD////l/1wA9wNbECMAcf/JAJ4QAgqxAAD//wBQ/34CFQLZECMAcQCO/QcQAgAvAAD////l/34A9wLZECMAcf/J/QcQAgBPAAD//wBQ/y4CFQLZECMCaQCP/N8QAgAvAAD////e/y4A/QLZECMCaf/K/N8QAgBPAAD//wBQAAAC/gOEECcYWQFeAAAQAgAwAAD//wA8AAAC8ALrECMAdgEbAAcQAgBQAAD//wBQAAAC/gNzECMCfAEIAKcQAgAwAAD//wA8AAAC8ALZECMCfAEMAA0QAgBQAAD//wBQ/1wC/gLZECMCfAD7/PgQAgAwAAD//wA8/1wC8AIbECMCfAD5/PgQAgBQAAD//wBQAAACigNwECMCfADCAKQQAgAxAAD//wA8AAAB3QLZECICfHsNEAIAUQAAAAD//wBQ/1wCigLZECMCfADC/PgQAgAxAAD//wA8/1wB3QIbECMCfABw/PgQAgBRAAD//wBQ/34CigLZECMAcQDE/QcQAgAxAAD//wA8/34B3QIbECMAcQBy/QcQAgBRAAD//wBQ/y4CigLZECMCaQDG/N8QAgAxAAD//wA8/y4B3QIbECMCaQBz/N8QAgBRAAD//wAo/+kC6APeECcYWQFyAFoQIwJ/AOsAlRACADIAAP//AB7/6QH4A3AQIwB2AJkAjBAiAn9u6BICAFIAAAAA//8AKP/pAugD6BAjAn8A6wCcECIAMgAAEAMAagDpARz//wAe/+kB+ANOECICf27tEiIAUgAAEAMAagB0AIIAAP//ACj/6QLoA9QQJxhYANwAUBAjAHEA4ACDEAIAMgAA//8AHv/pAfgDXBAiAHFo4hAiAENUeBICAFIAAP//ACj/6QLoA9QQJxhZASwAUBAjAHEA6ACDEAIAMgAA//8AHv/pAfgDWBAiAHFo4hAjAHYAhQB0EgIAUgAAAAD//wBQAAACXgOEECcYWQDmAAAQAgAzAAD//wA8/yYCEQLrECMAdgCcAAcQAgBTAAD//wBQAAACXgNzECMCfACgAKcQAgAzAAD//wA8/yYCEQLZECMCfACDAA0QAgBTAAD//wBQAAACmgNzECMCfAC5AKcQAgA1AAD//wA8AAABOALZECICfBwNEAIAVQAAAAD//wBQ/1wCmgLZECMCfADH/PgQAgA1AAD//wA7/1wBOAIbECMCfP/I/PgQAgBVAAD//wBQ/1wCmgNnECMAcQC6AKoQAgrUAAD//wA7/1wBTQKdECIAcR/gEgIK1QAAAAD//wBQ/34CmgLZECMAcQDJ/QcQAgA1AAD////m/34BOAIbECMAcf/K/QcQAgBVAAD//wAw/+kCbQOBECMCfACiALUQAgA2AAD//wAi/+kBywLZECICfFENEAIAVgAAAAD//wAw/0UCbQLlECMCfACp/OEQAgA2AAD//wAi/0UBywIbECMCfABM/OEQAgBWAAD//wAw/+kCbQPoECcYWQEi//YQIgA2AAAQAwJ8ALQBHP//ACL/6QHLA14QIwJ8AE0AkhACAR0AAP//ADD/6QJtA+gQJxhbAKgAABAiADYAABADAnwApgEc//8AIv/pAcsDVBAjAnwAUACIEAIBIwAA//8AMP9FAm0DcxAjAnwAogCnEAIK3AAA//8AIv9FAcsC2RAiAnxRDRACCt0AAAAA//8AHgAAAloDcxAjAnwAjACnEAIANwAA//8AFP/pAQQDQBAiAnzXdBACAFcAAAAA//8AHv9cAloC2RAjAnwAjPz4EAIANwAA//8AFP9FAQQCnBAjAnwAE/zhEAIAVwAA//8AHv9+AloC2RAjAHEAjv0HEAIANwAA//8AFP9nAUMCnBAjAHEAFfzwEAIAVwAA//8AHv8uAloC2RAjAmkAkPzfEAIANwAA//8AFP8XAUkCnBAjAmkAFvzIEAIAVwAA//8AUP9GAoAC2RAjAGoAyfziEAIAOAAA//8APP9GAd0CDBAjAGoAbvziEAIAWAAA//8AUP9FAoAC2RAjAn8AyvzgEAIAOAAA//8APP9FAd0CDBAjAn8AaPzgEAIAWAAA//8AUP8XAoAC2RAjAmkAyPzIEAIAOAAA//8APP8XAd0CDBAjAmkAY/zIEgIAWAAA//8AUP/pAoAD1BAnGFkBXgBQECMCfwDQAIcQAgA4AAD//wA8/+kB3QNsECMAdgCPAIgQIgJ/bugQAgBYAAAAAP//AFD/6QKAA8wQIwBxAMYAfBAiADgAABADAGoAygEA//8APP/pAd0DPxAiAHFs4hIiAFgAABACAGpvc///AA8AAAJ2A24QIwJ/ALAAoRACADkAAP//AAoAAAHmAr8QIgJ/VvIQAgBZAAAAAP//AA//XAJ2AtkQIwJ8AK/8+BACADkAAP//AAr/XAHmAgwQIwJ8AEj8+BACAFkAAP//AA8AAAOaA4QQJxhYAUAAABACADoAAP//AAoAAALIAusQIwBDAJwABxACAFoAAP//AA8AAAOaA4QQJxhZAYYAABACADoAAP//AAoAAALIAusQIwB2AOsABxACAFoAAP//AA8AAAOaA28QIwBqATgAoxACADoAAP//AAoAAALIAtoQIwBqAMIADhACAFoAAP//AA8AAAOaA3MQIwJ8ATQApxACADoAAP//AAoAAALIAtkQIwJ8AL4ADRACAFoAAP//AA//XAOaAtkQIwJ8ATb8+BACADoAAP//AAr/XALIAgwQIwJ8AL38+BACAFoAAP//AA8AAAKCA3MQIwJ8AKoApxACADsAAP//AAoAAAHSAtkQIgJ8UA0QAgBbAAAAAP//AA8AAAKCA3AQIwBqAK4ApBACADsAAP//AAoAAAHSAtoQIgBqVA4QAgBbAAAAAP//AA8AAAKXA3MQIwJ8AKoApxACADwAAP//AAr/JgHUAtkQIgJ8Ug0QAgBcAAAAAP//AB4AAAJJA4QQJxhaAKAAABACAD0AAP//AB4AAAHIAtkQIgJpVPQQAgBdAAAAAP//AB7/XAJJAtkQIwJ8AIr8+BACAD0AAP//AB7/XAHIAgwQIwJ8AE38+BACAF0AAP//AB7/fgJJAtkQIwBxAIz9BxACAD0AAP//AB7/fgHIAgwQIwBxAE/9BxACAF0AAP//ADz/fgHcAtkQIwBxAHH9BxACAEsAAP//AAD/6QEbA0IQIgBq53YQAgBXAAAAAP//AAoAAALIAwQQIwJ9AL4AABACAFoAAP//AAr/JgHUAwMQIgJ9Uv8QAgBcAAAAAP//AB7/6QILAvIQIwJhAVoAABACAEQAAP//ABQAAAEEA4AQIwJ8ABsAtBACAUEAAAABABIAAAECAtwAGABmALIBAAArsg0DACu0EgQAQwQrsggBACu0BwQAKwQrAbAZL7AB1rEFCTIytAAFADwEK7AUMrIAAQors0AAFwkrsAAQtAQFAA4EK7AEL7AHM7EaASsAsQcBERKxFRc5ObAIEbAWOTAxMyMRBzU3NSM1MzU0NjMyFxUmIyIdATcVB6tTRkZGRkE6FxgTCjo7OwE3MEAwUURZOD8FRQE1rihAKAAAAAEAEgAAAQIC3AAYAGsAsgEAACuyDQMAK7QSBABDBCuyBwEAK7AXM7QIBAArBCuwFTK0BAMBCA0rtAQEACsEKwGwGS+wAdaxBQkyMrQABQA8BCuwFDKyAAEKK7NAABcJK7APMrIBAAors0ABAwkrsAcysRoBKwAwMTMjESM1MzUjNTM1NDYzMhcVJiMiHQEzFSOrU0ZGRkZBOhcYEwo6V1cBgkRIRBM4PwVFATUMRAAAAQBd/+kCcwLlACQAhwCyCgAAK7IaAAArsR8E6bIOAwArsQUE6bQAJBoODSuxAATpAbAlL7AK1rEJBemwCRCxIQErsRcF6bAXELARINYRsQMF6bADL7ERBemyAxEKK7NAAyQJK7EmASuxAwkRErMOGhwfJBc5sCERsBQ5ALEkHxESsRcdOTmwABGwFDmwBRKwETkwMQEyNjQmIyIGFREjETQ2MzIWFRQGBx4BFRQGIyInNRYzMjU0JiMBXlM+S0lST12Qb22GKx8sQn5qTS41PZZeXAGxOGY9S0P+AgIUWHluUzpLDw1qL4CBF10dlk86AAAA//8AHv/wAgoC2RAGA0cAAP//AA//XAKLAtkQIwJ8AKj8+BACACQAAP//AB7/RQILAhsQIwJ8AG384RACAEQAAP//AA8AAAKLA8kQIwKsAiMA1BICACQAAP//AB7/6QILAxIQIwKsAfAAHRICAEQAAP//AA8AAAKLA+gQJxhaAKoAABAnGFkBmQBkEAIAJAAA//8AHv/pAh8DbBAjAHYA8gCIEAIApAAA//8ADwAAAosD6BAnGFoAuwAAECYYWB5kEAIAJAAAAAD//wAE/+kCCwNsECMAQ//uAIgQAgCkAAD//wAPAAACiwPoECcYWgCqAAAQIgAkAAAQAwKsAvAA8///AB7/6QILA3QQIwKsAowAfxICAKQAAP//AA8AAAKLA94QJxhaAKr/3hAiACQAABADAn8ArgER//8AHv/pAgsDYxAjAn8AcgCWEAIApAAA//8AD/9cAosDhBAnGFoAqgAAEAILGgAA//8AHv9FAgsC7RAiAmlwCBACCxsAAAAA//8ADwAAAosD6BAnGFkBGABkECMCewC7AJ0QAgAkAAD//wAe/+kCCwN8ECMAdgCOAJgQAgDFAAD//wAPAAACiwPoECcYWACqAGQQIwJ7ALEAlBACACQAAP//AB7/6QILA3oQIwBDAGUAlhACAMUAAP//AA8AAAKLBBoQIwJ7ALsAnhAiACQAABADAqwCQAEl//8AHv/pAgsDlBAjAqwCBQCfEgIAxQAA//8ADwAAAosEBxAjAnsAuwCiECIAJAAAEAMCfwDDATr//wAe/+kCCwNxECMCfwByAKQQAgDFAAD//wAP/1wCiwN8ECMCewCsAKAQAgsaAAD//wAe/0UCCwLeECICe24CEAILGwAAAAD//wBQ/1wCWwLZECMCfAC4/PgQAgAoAAD//wAe/0UB9wIbECMCfABv/OEQAgBIAAD//wBQAAACWwPQECMCrAIrANsSAgAoAAD//wAe/+kB9wMSECMCrAHuAB0SAgBIAAD//wBQAAACWwOFECMCfwC0ALgQAgAoAAD//wAe/+kB9wK/ECICf3byEAIASAAAAAD//wBQAAACdgPoECcYWgCgAAAQJxhZAYgAZBACACgAAP//AB7/6QIeA2wQIwB2APEAiBACAKwAAP//ACoAAAJbA+gQJxhaALQAABAmGFgeZBACACgAAAAA//8ABP/pAfcDbBAjAEP/7gCIEAIArAAA//8AUAAAAl8D6BAnGFoAoAAAECIAKAAAEAMCrALiAPP//wAe/+kCFANgECMCrAKXAGsSAgCsAAD//wBQAAACWwPoECcYWgCq/+wQIgAoAAAQAwJ/ALEBG///AB7/6QH3A2EQIwJ/AHwAlBACAKwAAP//AFD/XAJbA4QQJxhaALQAABACCzIAAP//AB7/RQH3AtsQIgJpdPYQAgszAAAAAP//AFMAAADsA9AQIwKsAW8A2xICACwAAP//ADoAAADTAwMQIwKsAVYADhICAPMAAP//AF//XADHAtkQIwJ8/+z8+BACACwAAP//ADn/XAChAtkQIwJ8/8b8+BACAEwAAP//ACj/RQLoAuUQIwJ8AN/84RACADIAAP//AB7/RQH4AhsQIwJ8AGr84RACAFIAAP//ACj/6QLoA9EQIwKsAmMA3BICADIAAP//AB7/6QH4AwgQIwKsAeoAExICAFIAAP//ACj/6QLoA+gQJxhaAOYAABAnGFkBygBkEAIAMgAA//8AHv/pAhYDaxAjAHYA6QCHEAIAtgAA//8AKP/pAugD6BAnGFoA5gAAECYYWE1kEAIAMgAAAAD//wAA/+kB+ANsECMAQ//qAIgQAgC2AAD//wAo/+kC6AOEECcYWgDjAAAQIgAyAAAQAwKsA0cAj///AB7/6QIvAwYQIwKsArIAERICALYAAP//ACj/6QLoA+gQJxhaANz/7BAiADIAABADAn8A5AEb//8AHv/pAfgDYBAjAn8AcACTEAIAtgAA//8AKP9FAugDhBAnGFoA3AAAEAILRgAA//8AHv9FAfgC7RAiAmlsCBACC0cAAAAA//8AKP/pAxYDhBAnGFkBNgAAEgIBYgAA//8AHv/pAi8C5BAjAHYAgQAAEgIBYwAA//8AKP/pAxYDhBAnGFgA8AAAEgIBYgAA//8AHv/pAi8C5BAiAENkABICAWMAAAAA//8AKP/pAxYD0BAjAqwCZwDbEgIBYgAA//8AHv/pAi8DBBAjAqwB8gAPEgIBYwAA//8AKP/pAxYDdBAjAn8A6wCnEgIBYgAA//8AHv/pAi8CwRAiAn9+9BICAWMAAAAA//8AKP9FAxYDHBAjAnwA3/zhEgIBYgAA//8AHv9FAi8CdxAjAnwAavzhEgIBYwAA//8AUP9FAoAC2RAjAnwAxfzhEAIAOAAA//8APP9FAd0CDBAjAnwAQfzhEAIAWAAA//8AUP/pAoADwxAjAqwCOADOEgIAOAAA//8APP/pAd0C7xAjAqwB9f/6EgIAWAAA//8AUP/pAwMDhBAnGFkBGAAAEgIBcQAA//8APP/pAmoC5BAjAHYAigAAEgIBcgAA//8AUP/pAwMDhBAnGFgA0gAAEgIBcQAA//8APP/pAmoC5BAiAENuABICAXIAAAAA//8AUP/pAwMDrRAjAqwCRQC4EgIBcQAA//8APP/pAmoC/hAjAqwB2AAJEgIBcgAA//8AUP/pAwMDcRAjAn8AzACkEgIBcQAA//8APP/pAmoCshAiAn9u5RICAXIAAAAA//8AUP9FAwMDWBAjAnwAxfzhEgIBcQAA//8APP9FAmoCixAjAnwAQfzhEgIBcgAA//8ADwAAApcDhBAnGFgAtAAAEAIAPAAA//8ACv8mAdQC5BAiAENGABACAFwAAAAA//8AD/9cApcC2RAjAnwArvz4EAIAPAAA//8ACv8mAdQCDBAjAnwAxv0IEAIAXAAA//8ADwAAApcDtRAjAqwCMgDAEgIAPAAA//8ACv8mAdQC7RAjAqwB1//4EgIAXAAA//8ADwAAApcDdRAjAn8ArwCoEAIAPAAA//8ACv8mAdQCsBAiAn9X4xACAFwAAAAA//8AHv/zAjUC5hAiDCR3AhACA0QAAAAA//8AHv/zAjUC5BAiDFxzABACA0QAAAAA//8AHv/zAjUC9BAiDDE+EBICA0QAAAAA//8AHv/zAjUC9BAiDD5GEBICA0QAAAAA//8AHv/zAjUC9BAiDDJLEBICA0QAAAAA//8AHv/zAjUC9BAiDD8+EBICA0QAAAAA//8AHv/zAjUDaxAiDDNxARACA0QAAAAA//8AHv/zAjUDaxAiDEBx/xACA0QAAAAA//8ADwAAAosC5RAiDCTZARICAyUAAAAA//8ADAAAAogC5RAiDFzSARICAyX9AAAA////8gAAAtYC5BAmDDGgABACAyVLAAAA////8wAAAuEC6xAiDD6vBxACAyVWAAAA////7wAAAqEC5RAiDDKtARACAyUWAAAA////7QAAAqgC5RAiDD+cARACAyUdAAAA////8QAAAo4DVBAiDDPk6hACAyUDAAAA////5QAAAogDVxAiDEDY6xACAyX9AAAA//8AHv/2AdMC4hAiDCRW/hACA0gAAAAA//8AHv/2AdMC4xAiDFxg/xACA0gAAAAA//8AHv/2AdMC9BAiDDEsEBICA0gAAAAA//8AHv/2AdMC9BAiDD40EBICA0gAAAAA//8AHv/2AdMC9BAiDDI4EBICA0gAAAAA//8AHv/2AdMC9BAiDD8sEBICA0gAAAAA////8wAAApoC5RAjDCT/fwABEAIDKT8A////7gAAAokC5RAjDFz/eAABEAIDKS4A////8AAAA0QC5RAiDDGeARADAykA6QAA////8QAAAzIC5RAiDD6tARADAykA1wAA////7wAAAyMC5RAiDDKtARADAykAyAAA////8QAAAy8C5RAiDD+gARADAykA1AAA//8AD/9KAekC8RAiDCRyDRACA0oAAAAA//8AD/9KAekC9BAiDFx0EBACA0oAAAAA//8AD/9KAekC9BAiDDE9EBICA0oAAAAA//8AD/9KAekC9BAiDD5PEBICA0oAAAAA//8AD/9KAekC9BAiDDJ8EBICA0oAAAAA//8AD/9KAekC9BAiDD9bEBICA0oAAAAA//8AD/9KAekDaxAiDDNmARACA0oAAAAA//8AD/9KAekDaxAiDEB4/xACA0oAAAAA////8QAAArMC5RAjDCT/fQABEAIDKzIA////9wAAArkC5RAiDFyBARACAys4AAAA////8gAAA2AC5RAiDDGgARADAysA3wAA////+AAAA2IC5RAiDD60ARADAysA4QAA////9AAAA14C5RAiDDKyARADAysA3QAA////9AAAA2EC5RAiDD+jARADAysA4AAA////3QAAAwQDVBAiDDPQ6hADAysAgwAA////3QAAAwQDVRAiDEDQ6RADAysAgwAA//8ALP/4ARIC9BAiDCS4EBACA0wAAAAA//8AOP/4ARIC9BAiDFzCEBACA0wAAAAA////9P/4ASYC9BAiDDGiEBICA0wAAAAA////9//4ASYC9BAiDD6zEBICA0wAAAAA////+//4ASEC9BAiDDK5EBICA0wAAAAA////+f/4ASgC9BAiDD+oEBICA0wAAAAA////y//4ARIDaxAiDDO+ARACA0wAAAAA////y//4ARIDaxAiDEC+/xACA0wAAAAA////8QAAAO4C5RAjDCT/fQABEAIDLSwA////9QAAAO0C5RAjDFz/fwABEAIDLSsA////8gAAAY4C5RAiDDGgARADAy0AzAAA////8QAAAZEC5RAiDD6tARADAy0AzwAA////8QAAAYkC5RAiDDKvARADAy0AxwAA////8wAAAZAC5RAiDD+iARADAy0AzgAA////4AAAATYDVhAiDDPT7BACAy10AAAA////3gAAATIDWhAiDEDR7hACAy1wAAAA//8AHv/2AgIC5RAiDCRnARACA1IAAAAA//8AHv/2AgIC5RAiDFxyARACA1IAAAAA//8AHv/2AgIC9BAiDDE6EBICA1IAAAAA//8AHv/2AgIC9BAiDD5CEBICA1IAAAAA//8AHv/2AgIC9BAiDDJHEBICA1IAAAAA//8AHv/2AgIC9BAiDD86EBICA1IAAAAA////7//pAuUC6BAjDCT/ewAEEAIDM/0A////9P/pAu4C6xAjDFz/fgAHEAIDMwYA////8v/pA7wC5RAiDDGg/hADAzMA1AAA////8//pA7kC5RAiDD6v+xADAzMA0QAA////8f/pA1UC5RAiDDKv/hACAzNtAAAA////8//pA18C5RAiDD+iARACAzN3AAAA//8APP/yAfIC5hAiDCRgAhACA1gAAAAA//8APP/yAfIC4xAiDFxo/xACA1gAAAAA//8APP/yAfIC9BAiDDExEBICA1gAAAAA//8APP/yAfIC9BAiDD46EBICA1gAAAAA//8APP/yAfIC9BAiDDJAEBICA1gAAAAA//8APP/yAfIC9BAiDD80EBICA1gAAAAA//8APP/yAfIDahAiDDNiABACA1gAAAAA//8APP/yAfIDaxAiDEBi/xACA1gAAAAA////7gAGAucC5RAjDFz/eAABEAIDOFAA////7wAGA48C5RAiDD6rARADAzgA+AAA////9AAGA8cC5RAiDD+jARADAzgBMAAA////7wAGA1sDVxAiDEDi6xADAzgAxAAA//8AHv/3AroC4xAjDCQAxv//EAIDXAAA//8AHv/3AroC4hAjDFwA0P/+EAIDXAAA//8AHv/3AroC9BAjDDEAnAAQEgIDXAAA//8AHv/3AroC9BAjDD4ApAAQEgIDXAAA//8AHv/3AroC9BAjDDIAqQAQEgIDXAAA//8AHv/3AroC9BAjDD8AnAAQEgIDXAAA//8AHv/3AroDahAjDDMAzAAAEAIDXAAA//8AHv/3AroDahAjDEAAzP/+EAIDXAAA////8wAAAsQC4hAjDCT/f//+EAIDPPcA////8QAAAskC5RAjDFz/ewABEAIDPPwA////8QAAA48C6BAiDDGfBBADAzwAwgAA////7wAAA40C6BAiDD6rBBADAzwAwAAA////8wAAAzIC4hAiDDKx/hACAzxlAAAA////7wAAA1kC3RAiDD+e2hADAzwAjAAA////9wAAA0gDVBAiDDPq6hACAzx7AAAA////8wAAA0gDVhAiDEDm6hACAzx7AAAA//8AHv/zAjUC6xAjDFAAlgAHEAIDRAAA//8AHv/zAjUC6xAiDFtQBxACA0QAAAAA//8AHv/2AdMC6xAjDFAAgwAHEAIDSAAA//8AHv/2AdMC6xAiDFs9BxACA0gAAAAA//8AD/9KAekC6xAjDFAAogAHEAIDSgAA//8AD/9KAekC6xAiDFtiBxACA0oAAAAA//8AAP/4ARIC6xAiDFDgBxICA0wAAAAA//8AOP/4ARIC6xAiDFvmBxICA0wAAAAA//8AHv/2AgIC6xAjDFAAiAAHEgIDUgAA//8AHv/2AgIC6xAiDFtWBxICA1IAAAAA//8APP/yAfIC6xAjDFAAhAAHEAIDWAAA//8APP/yAfIC6xAiDFtYBxACA1gAAAAA//8AHv/3AroC6xAjDFAA9AAHEAIDXAAA//8AHv/3AroC6xAjDFsArgAHEAIDXAAA//8AHv85AjUC5hAiAxVqARACC3QAAAAA//8AHv85AjUC5BAiAxVqARACC3UAAAAA//8AHv85AjUC9BAiAxVqARICC3YAAAAA//8AHv85AjUC9BAiAxVqARICC3cAAAAA//8AHv85AjUC9BAiAxVqARICC3gAAAAA//8AHv85AjUC9BAiAxVqARICC3kAAAAA//8AHv85AjUDaxAiAxVqARACC3oAAAAA//8AHv85AjUDaxAiAxVqARACC3sAAAAA//8ADwAAAy8C5RAjDCMCfAAAEAILfAAA//8ADAAAAy0C5RAjDCMCegAAEAILfQAA////8gAAA4UC5BAjDCMC0gAAEAYLfgAA////8wAAA4UC6xAjDCMC0gAAEAILfwAA////7wAAA0YC5RAjDCMCkwAAEAILgAAA////7QAAA00C5RAjDCMCmgAAEAILgQAA////8QAAAzQDVBAjDCMCgQAAEAILggAA////5QAAAywDVxAjDCMCeQAAEAILgwAA//8AD/84AekC8RAiAxXMABACC5AAAAAA//8AD/84AekC9BAiAxXLABACC5EAAAAA//8AD/84AekC9BAiAxXNABACC5IAAAAA//8AD/84AekC9BAiAxXQABACC5MAAAAA//8AD/84AekC9BAiAxXQABACC5QAAAAA//8AD/84AekC9BAiAxXRABACC5UAAAAA//8AD/84AekDaxAiAxXQABACC5YAAAAA//8AD/85AekDaxAiAxXQARACC5cAAAAA////8QAAA5EC5RAjDCMC3gAAEAILmAAA////9wAAA5QC5RAjDCMC4QAAEAILmQAA////8gAABEEC5RAjDCMDjgAAEAILmgAA////+AAABEYC5RAjDCMDkwAAEAILmwAA////9AAABDwC5RAjDCMDiQAAEAILnAAA////9AAABD8C5RAjDCMDjAAAEAILnQAA////3QAAA+IDVBAjDCMDLwAAEAILngAA////3QAAA+UDVRAjDCMDMgAAEAILnwAA//8AHv85AroC4xAjAxUAwAABEAILyAAA//8AHv85AroC4hAjAxUAwAABEAILyQAA//8AHv85AroC9BAjAxUAwAABEAILygAA//8AHv85AroC9BAjAxUAwAABEAILywAA//8AHv85AroC9BAjAxUAwAABEAILzAAA//8AHv85AroC9BAjAxUAwAABEAILzQAA//8AHv85AroDahAjAxUAwAABEAILzgAA//8AHv85AroDahAjAxUAwAABEAILzwAA////8///A5cC4hAjDCMC5P//EAIL0AAA////8f//A5cC5RAjDCMC5P//EAIL0QAA////8QAABFsC6BAjDCMDqAAAEAIL0gAA////7///BFkC6BAjDCMDpv//EAIL0wAA////8wAABAYC4hAjDCMDUwAAEAIL1AAA////7wAABCYC3RAjDCMDcwABEAIL1QAA////9///BBcDVBAjDCMDZP//EAIL1gAA////8///BBoDVhAjDCMDZ///EAIL1wAA//8AHv/zAjUC3hAiAntuAhACA0QAAAAA//8AHv/zAjUCnRAiAHFv4BACA0QAAAAA//8AHv85AjUC6xAiAxVqARACC9gAAAAA//8AHv85AjUCExAiAxVqARACA0QAAAAA//8AHv85AjUC6xAiAxVqARACC9kAAAAA//8AHv/zAjUCvxAiAn9y8hACA0QAAAAA//8AHv85AjUCvxAiAxVqARACDBsAAAAA//8ADwAAAosDgxAjAnsAqgCnEAIDJQAA//8ADwAAAosDZxAjAHEAqgCqEAIDJQAA////3QAAAosC5RAiDFC9ARACAyUAAAAA//8ABQAAAosC5RAiDFuzARACAyUAAAAA//8ADwAAAzEC2RAjDCMCfgAAEAIDJQAA//8AdAJBAMwC5BAGDCQAAAABABcAAACzALIAEQBJALIJAAArtAAEABMEK7IACQors0AABQkrs0AADAkrAbASL7AL1rQPBQAmBCuwDxCxBQErtAYFABEEK7ETASuxDwsRErAJOQAwMTcyPgI3MxQGIyI9ATMdARQWfQsKAwQBGSExSkwKJQMDDgQqE09jEzIoIAAAAP//AHQCQQDMAuQQAwK2AUIAAAAA//8ADQJsAUcC1BACAn8IB///AA0CeQFHA4QQIwwlAAAAsBACAGoAFf//AA//OAHpAusQIgMVzQAQAgvcAAAAAP//AA//OgHpAhMQIgMVzwIQAgNKAAAAAP//AA//OQHpAusQIgvdAAAQAgMVywEAAP//AA//SgHpAuAQIgJ/bRMQAgNKAAAAAP//AA//OAHpAuAQIgMVzAAQAgwqAAAAAP////cAAAMFAuUQIgxQ1wEQAwMpAKoAAP///+MAAALIAuUQIgxbkQEQAgMpbQAAAP//ABAAAAM/AuUQIgxQ8AEQAwMrAL4AAP//AAYAAAMsAuUQIgxbtAEQAwMrAKsAAP//AFAAAANcAtkQIwwjAqkAABACAysAAP//AFICQQGEAuQQIwxQAJMAABACDCTeAP//AEICQQFoAuQQIgxbRQAQAgwkzgAAAP//AA0COQFHA2oQJwwlAAAAlhACDCQK+P///83/+AESAt4QIgJ7vgIQAgNMAAAAAP///9v/+AESAp0QIgBxv+AQAgNMAAAAAP///+P/+AEqAv0QIgxOwfMQAgNMAAAAAP///+//+AE2AvgQIgxPze4QAgNMAAAAAP///8f/+AESAr8QIgJ/wvIQAgNMAAAAAP////D/+AEqA2wQJgwm4+gQAgNMAAAAAP////0AAAEqA4QQIwJ7/+4AqBICAy0AAP//AAIAAAEUA2YQIwBx/+YAqRICAy0AAP///+UAAAEtAuUQIgxQxQEQAgMtawAAAP///+IAAAEkAuUQIgxbkAEQAgMtYgAAAP//AEQCQQFzAuQQIwxQAIIAABACDFzOAP//AFECQQGAAuQQIgxbXQAQAgxc2wAAAP//AA0COQFHA2wQJwwlAAAAmBACDFwD+P//ADz/8gHyAt4QIgJ7XgIQAgNYAAAAAP//ADz/8gHyAp0QIgBxXuAQAgNYAAAAAP//ADz/8gHyAv0QIgxOPvMQAgNYAAAAAP//ADz/8gHyAvsQIgxPPvEQAgNYAAAAAP//ADz/OAIgAuUQIgwkfgEQAgNUAAAAAP//ADz/OAIgAuUQIwxcAIgAARACA1QAAP//ADz/8gHyAr8QIgJ/YfIQAgNYAAAAAP//ADz/8gHyA2sQIgNYAAAQBgwmXOcAAP//AA8ABgKXA4QQIwJ7ALAAqBACAzgAAP//AA8ABgKXA2cQIwBxALEAqhACAzgAAP///9oABgMtAuUQIgxQugEQAwM4AJYAAP///8kABgM3AuUQIwxb/3cAARADAzgAoAAAAAD////zAAACpwLlECMMXP99AAEQAgM1SQAAAwAiAmwBaQMKAAMABwALAEcAsgcCACuwCDOxBgTpsQEJMjIBsAwvsAbWtAUFADwEK7AFELEKASu0CQUAPAQrsQ0BK7EFBhESsAM5sAoRsgACATk5OQAwMRMXIycXFSM1IRUjNb5BOmESUwFFUwMKnp5JU1NTUwD//wAiAmwBaQMKEAYDGxwA//8AIAJQAPEC5BACAEMKAP//AB7/OQK6AusQIwMVAMAAARACC+QAAP//AB7/OQK6Ag4QIwMVAMAAARACA1wAAP//AB7/OQK6AusQIwMVAMAAARACC+UAAP//AB7/9wK6Ar8QIwJ/AND/8hACA1wAAP//AB7/OQK6Ar8QIwMVAMAAARACDFQAAP///7//6QMkAuUQIgxQn/4QAgMzPAAAAP///+r/6QMkAuUQIgxbmPgQAgMzPAAAAP///8cAAAMTAt0QIgxQp/UQAgM8RgAAAP///9oAAALxAt0QIgxbiN0QAgM8JAAAAP//ACgAAAOYAt0QIwwjAuUAAhACAzwAAP//AFICUAEjAuQQAgB29gD//wB2AkEAzgLkEAMCtwFKAAAAAAABAC4A8AEcATgAAwAoALACL7QDBAA3BCu0AwQANwQrAbAEL7ECASu0AQUACQQrsQUBKwAwMQEVIzUBHO4BOEhIAAAA//8ALgDwARwBOBACDG0AAP//AEQA8AHoATgQAgxwHAAAAQAoAPABzAE4AAMAHQCwAi+0AwQANwQrtAMEADcEKwGwBC+xBQErADAxARUhNQHM/lwBOEhIAAABACgA8APAATgAAwAdALACL7QDBAA3BCu0AwQANwQrAbAEL7EFASsAMDEBFSE1A8D8aAE4SEgA//8AKADwA8ABOBACDHEAAP//AEb/8gD6AqQQBg3dAAD////t/uoCRf+CEAcC1gJGAAAAAAABAGEB8gC+AtoACAA3ALIEAwArtAUEABMEK7ABL7QHBAAdBCsBsAkvsAHWsQAF6bEABemwBDK0BwUAEQQrsQoBKwAwMRMjNTQ3FQYVM75dXS8vAfJlewgmClAAAAEAUAHxAK0C2QAIAD8AsgADACu0CAQAHQQrsgUBACu0BAQAEwQrAbAJL7AE1rAAMrECBemxAgXpsAIQtAcFABEEK7AHL7EKASsAMDETMxUUBzU2NSNQXV0vLwLZZXsIJgdTAAABAFD/gACtAGgACAA9ALIIAAArtAAEAB0EK7AEL7QFBAATBCsBsAkvsATWsAAysQIF6bECBemwAhC0BwUAEQQrsAcvsQoBKwAwMTczFRQHNTY1I1BdXS8vaGV7CCYHUwABAGEB8QC+AtkACQAtALIJAwArtAIEAB0EKwGwCi+wCNaxAQXpsQEF6bAFMrQCBQARBCuxCwErADAxExUjFBYXFSY9Ab4vFRpdAtloLCoEJgh7Zf//AFkB8gFUAtoQJwx1AJYAABAGDHX4AP//AFAB8QFNAtkQJwx2AKAAABAGDHYAAP//AFD/gAFNAGgQJwx3AKAAABAGDHcAAP//AFcB8QFUAtkQJwx4AJYAABAGDHj2AAABACb/TwIBAsUACwBMALIJAgArsAYvsAEzsQcE6bAAMrIGBwors0AGBAkrAbAML7AE1rAIMrEDBemwCjKyAwQKK7NAAwEJK7IEAwors0AEBgkrsQ0BKwAwMQEVIxEjESM1MzUzFQIBwljBwVgB9lL9qwJVUs/PAAABACb/TwIBAsUAEwBjALIRAgArsAovsAUzsQsE6bADMrIKCwors0AKCAkrsA4vsAEzsQ8E6bAAMgGwFC+wCNaxDBAyMrEHBemxAhIyMrIHCAors0AHBQkrsAAysggHCiuzQAgKCSuwDjKxFQErADAxARUjETMVIxUjNSM1MxEjNTM1MxUCAcLCwljBwcHBWAH2Uv7NUtDQUgEzUs/PAAAAAQBLANwBRQHWAAkALgCwBi+0AQQACAQrtAEEAAgEKwGwCi+wCda0AwUACAQrtAMFAAgEK7ELASsAMDESMhYVFAYjIiY0lGhJSjM0SQHWSjUySUloAAAAAAEAWgDcAUAB1gAEACEAsAQvtAAEAAgEKwGwBS+xBAErtAIFAAkEK7EGASsAMDETFhUwB1rm5gHWfAF9//8AxgAAAS4AaBAGABF2AP//AF4AAAGWAGgQJwARAN4AABAGABEOAP//AFAAAAJYAGgQJwARANAAABAnABEBoAAAEAYAEQAA//8AVwDjAL8BSxAGAHkAAAAHAAn/6gPhAuIACgAVABkAJAAuADkAQwDiALIgAAArsRg1MzO0KgQAHwQrsD4yshYDACuwACDWEbQLBAAfBCu0JRogFg0rsC8ztCUEAB8EK7A6MrQRBiAWDSu0EQQAHwQrAbBEL7AJ1rQOBQARBCuwDhCxEwErtAMFABEEK7ADELEjASu0KAUAEQQrsCgQsSwBK7QdBQARBCuwHRCxOAErtD0FABEEK7A9ELFBASu0MgUAEQQrsUUBK7ETDhESswYAGBkkFzmxLCgRErMWGiAXJBc5sUE9ERKxNS85OQCxJSoRErUiIx0yNzgkFzmxCxERErIICQM5OTkwMRMyFhUUBiMiJjQ2FyIGFRQWMjY1NCYlMwEjATIWFRQGIyImNDYXIgYUFjI2NTQmJTIWFRQGIyImNDYXIgYUFjI2NTQmnj9XWD0+WFg9JTU2SjU1AShC/nVCAYI/V1g9PlhYPSU1NUo2NQFCP1dYPT5YWD0lNTVKNjUC2FhAPVhZfFg8NSUmNTUlJjVG/QoBK1hAPVhZfFg8NUo2NSUmNTxYQD1YWXxYPDVKNjUlJjUAAAkACf/qBUkC4gAKABQAHwApADQAPwBDAE4AWAEUALJKAAArsgYbQjMzM7RUBAAfBCuxDyQyMrJAAwArsCog1hG0NQQAHwQrtE9ESkANK7EAFTMztE8EAB8EK7ELIDIytDswSkANK7Q7BAAfBCsBsFkvsDPWtDgFABEEK7A4ELE9ASu0LQUAEQQrsC0QsU0BK7RSBQARBCuwUhCxVgErtEcFABEEK7BHELEJASu0DgUAEQQrsA4QsRIBK7QDBQARBCuwAxCxHgErtCMFABEEK7AjELEnASu0GAUAEQQrsVoBK7E9OBESszAqQkMkFzmxVlIRErNAREpBJBc5sRIOERKxBgA5ObEnIxESsRsVOTkAsU9UERJACQgJAxgdHkdMTSQXObE1OxESsjIzLTk5OTAxATIWFRQGIyImNDYXIgYUFjI2NTQmJTIWFRQGIyImNDYXIgYUFjI2NTQmATIWFRQGIyImNDYXIgYVFBYyNjU0JiUzASMBMhYVFAYjIiY0NhciBhQWMjY1NCYDSz9XWD0+WFg9JTU1SjY1AUI/V1g9PlhYPSU1NUo2NfvFP1dYPT5YWD0lNTZKNTUBKEL+dUIBgj9XWD0+WFg9JTU1SjY1ARdYQD1YWXxYPDVKNjUlJjU8WEA9WFl8WDw1SjY1JSY1Af1YQD1YWXxYPDUlJjU1JSY1Rv0KAStYQD1YWXxYPDVKNjUlJjUAAQAxAbYA4gLMAAUAIACwAy+0AAQACAQrAbAGL7AE1rQBBQAMBCuxBwErADAxExcPASc3jVU4VSQkAswodngRjgAAAAACADEBtgG1AswABQALABwAsAMvsAkztAAEAAgEK7AGMgGwDC+xDQErADAxExcPASc3JRcPASc3jVU4VSQkAQtVOFUkJALMKHZ4EY53KHZ4EY4AAAADADEBtgKIAswABQALABEAIACwCS+xAw8zM7QGBAAIBCuxAAwyMgGwEi+xEwErADAxARcPASc3JxcPASc3JRcPASc3AWBVOFUkJJtVOFUkJAHeVThVJCQCzCh2eBGOdyh2eBGOdyh2eBGOAAABADEBtgDiAswABQAgALADL7QABAAIBCsBsAYvsAXWtAIFAAwEK7EHASsAMDETHwEHLwGGNyUlVTcCzHeOEXh2AAAAAAIAMQG2AbUCzAAFAAsAHACwCS+wAzO0BgQACAQrsAAyAbAML7ENASsAMDEBHwEHLwIfAQcvAQFZNyUlVTd+NyUlVTcCzHeOEXh2KHeOEXh2AAAAAAMAMQG2AogCzAAFAAsAEQAgALAPL7EDCTMztAwEAAgEK7EABjIyAbASL7ETASsAMDEBHwEHLwElHwEHLwElHwEHLwEBWTgkJFU4ASg4JCRVOP6vOCQkVTgCzHeOEXh2KHeOEXh2KHeOEXh2AAEACf9VAW8AeQAFABkAsAAvsAMztAUEAAcEKwGwBi+xBwErADAxBSMnByMTAW46eHg6sqvKygEkAAAAAAEAMQBqAMkBtgAGAC0AsAYvtAIEAAcEKwGwBy+wANa0BQUADgQrsAMysQgBK7EFABESsQIEOTkAMDE3NTcVBxcVMZhqauNZelNTU1MAAAD//wAxAGoAyQG2EA8MlgD6AiDAAAAFAGIARAIMAewACQATAB0AKAA0ALEAsB4vsTI0MzOxJATpsAgvsBczsQME6bAbMrQtBAAfBCuwDy+xCgTpsSwuMjIBsDUvsAHWsSkrMjK0BQUAJgQrsAUQsSEBK7ARMrQnBQAbBCuwDDKwJxCxGgErtBQFACYEK7EvMTIysTYBK7EFARESsSw0OTmxJyERErMqLTAzJBc5sRQaERKxLjI5OQCxJB4RErEpMTk5sS0IERK0ARoqMDMkFzmxCg8RErErLzk5MDESNDYyFhcUBgciNzIWFAYiJjU0NhcOASMuATQ2MhYHIiY1NDYzMhYUBic3JzcXNxcHFwcnB2IYHBcBGA4OvQ4XFxwXFeUBGA0OGBgcGNUNGBYQDhYX47y8Gru7Gry8Gru7AQocGBgODRgB+hccFxYQDRfUDhgBFxwYGOIVEA4XFxwXGLy8GLu7GLy8GLu7AAAA//8AfAAAAeYC2RAmAAQAABAHAAQBFgAAAAMATQAAAf0C5QADABoAIQBgALICAAArtAMEAB0EK7IYAwArAbAiL7AV1rEUBemwFBCxAgErsQwQMjKxAQXpsQobMjKwARCxHwErsQQF6bEjASuxAQIRErEPGDk5sB8RsAg5ALEYAxESsgsbHDk5OTAxJRUjNQEUDgMdASM1NDcnEQ4BFSM0NjMyFicVNzY1NCYBSloBDSU0NSVaCQkrI1VvbGF0sw5LMGhoaAG9LkoxLTkgLzchFVMBCA5FQXN3aBb/DUNBKjoAAf/qAvACLAMmAAMAHQCwAi+0AwQAHwQrtAMEAB8EKwGwBC+xBQErADAxARUhNQIs/b4DJjY2AAABADv/OQJY/+QADAATALAHL7EABOkBsA0vsQ4BKwAwMQUyNzAVDgEjIiYnNRYBSLdZOYBVVoA5WXVZQDkyMjlAWQAAAAEAOwI+AlgC6QAMABMAsAAvsQcE6QGwDS+xDgErADAxASIHMDU+ATMyFhcVJgFLt1k5gFVWgDlZApdZQDkyMjlAWQAAAQAj/zcBkwEUAAcAAAEzBxcjJwcjAUQ+iZo+e3k+ARTi+8jIAAAA//8ACgACAzYC2RAnAA0B3/5JECcADf/i/koQBwANAN8AAAAAAAEAMgChAV4BQQADACgAsAIvtAMEAA0EK7QDBAANBCsBsAQvsQIBK7QBBQAHBCuxBQErADAxARUhNQFe/tQBQaCgAAAAAf9O/+wBWgLZAAMAFgCyAwAAK7IAAwArAbAEL7EFASsAMDEBMwEjARw+/jI+Atn9EwAAAAEAef8sARQC2QAhAEoAshQDACu0FwQAKwQrsAcvtAQEACsEKwGwIi+wCtawEDK0AQUAJgQrsBoysgEKCiuzQAEGCSuxFR4yMrEjASsAsRcEERKwDTkwMTcVFBY7ARUjIiY9ATQ3LgE9ATQ2OwEVIyIGHQEUFhcVDgHGGiUPLjQ5Ui4kOTQuDyUaIiwsIlamJxxBRT62eCYSRkW2PkVBHCemRjsJRQk8AAEAH/8sALoC2QAhAEoAsg0DACu0DAQAKwQrsBwvtB0EACsEKwGwIi+wIdawBzK0GAUAJgQrsBEysiEYCiuzQCEcCSuxAwwyMrEjASsAsQwdERKwFTkwMTc0Jic1PgE9ATQmKwE1MzIWHQEUBgcWHQEUBisBNTMyNjVtIiwsIholDy40OSQuUjk0Lg8lGlZFPAlFCTtGpiccQUU+tkVGEiZ4tj5FQRwn//8ATQAABCkC5RAjACICLAAAEAIAIgAA//8ATQAAAvwC5RAnAAQCLAAAEAIAIgAA//8AfAAAAxMC5RAmAAQAABADACIBFgAAAAEALv/0AggBnAAKADIAsgUAACuwCS+xCgTpAbALL7AF1rEEBemyBAUKK7NABAEJK7EMASsAsQoJERKwATkwMQEVDgEHIz4BNyE1AghRShtiFkZh/oEBnEpnlGNUe4JXAAEAMP9PAgoC2QAPAFMAsgwDACu0CwQAHwQrsAYysgsMCiuzQAsJCSuwBDIBsBAvsAnWtAgFABsEK7IJCAors0AJDAkrsAgQsQUBK7QEBQAbBCu0AAUACAQrsREBKwAwMQEUBgcRIxEjESMRIzUzMhYCCm1iQFJAOfpeggHpXoMF/kwDSvy2A0pAiwAAAgAfAEoB+gIgAA4AEgBMALAAL7QQBAAfBCuwDDKwDy+wCjO0CAQAHwQrAbATL7AE1rQQBQAIBCuwEBCxEQErtAwFABsEK7IMEQors0AMDQkrsAkysRQBKwAwMTciLgE1ND4BMyEVIxEzFQMRMxHuQmAtLWBCAQs5OctSSkRpPj1oRkD+qkABlv6qAVYAAAAAAgAgAEoB+gIgAA4AEgBUALABL7QCBAAfBCuwETKwBS+wDzO0BgQAHwQrAbATL7AD1rQRBQAbBCuyAxEKK7NAAwUJK7ABMrARELESASu0CwUACAQrsRQBKwCxBQIRErALOTAxJSE1MxEjNSEyHgEVFA4BAyMRMwEr/vU5OQELQmAtLWCCUlJKQAFWQENpPz5pRAGW/qoAAP//ACgAAgFXASIQBwANAAD+SQAAAAIAP/9tAKgCDAAKAA4ATwCyAgAAK7QKBAAdBCuyCwEAK7QOBAAdBCuwBy+0BgQAEwQrAbAPL7AJ1rALMrQBBQAwBCuwDDK0AQUAMAQrsAYytAMFABEEK7EQASsAMDE3FSMVFBYXFSI9AREzFSOoNxUiaWhoaGgSNSUBJoN4AaRoAAAAAAIAOwAVAlgCzgAMABgAKwCwBy+xAATpsA0vsRME6QGwGS+xGgErALENABEStwIECgsPEBYXJBc5MDElMjcwFQ4BIyImJzUWEyIHNT4BMzIWFxUmAUu0WTmAVlWAOVm3t1k5gFVWgDlZZ1lAOTIyOUBZAhVZQDkyMjlAWf//ACgAAgFXAuUQJgANAAwQBwANAAD+Sf//ADwAAQJIAu4QJwyhAO4AFRAnAHn/5QGQEAcAeQF//x4AAAABAAEBJQHxAY8AFwCAALAEL7EFDDMztBUEAB8EK7MKFQQIK7QQBAAfBCsBsBgvsRkBK7A2GrrtIMLZABUrCrAFLg6wCMCxEwv5sBLAsAgQswYIBRMrswcIBRMrsgcIBSCKIIojBg4REjmwBjkAtAcIEhMGLi4uLi4BtQcIEhMFBi4uLi4uLrBAGgEAMDEBMw4BIyImLwEmIyIHIz4BMzIfARYzMjYBxSsXSD4dLy0jIxo1GCsQTzg1NCQwIBkjAY85MQkPCwsuMTQSDA8WAAAAAQA7/zQCWP/fAAwAEwCwAC+xBwTpAbANL7EOASsAMDEFIgcwNT4BMzIWFxUmAUu3WTmAVVaAOVlzWUA5MjI5QFkAAAABACT/8gLvAr0AYQB5ALI2AAArsgYCACu0TFE2Bg0rsBsztEwEABIEK7AgMgGwYi+wOdawAzK0MwUAJAQrsAgysWMBK7EzORESQAkFAAsNLjA8PmAkFzkAsUw2ERK1KC4rPkFEJBc5sFERQAkWHRgjJUdJVFYkFzmwBhK0DRATWWAkFzkwMQEnJjU0NjIWFRQPARYXNzYzMhYVFA8BFhc3NjMyFhQGIyIvAQYHFxYVFAYjIi8BBgcXFhUUBiMiJjU0PwEmJwcGIyImNTQ/ASYnBwYjIiY0NjMyHwE2NycmNTQ2MzIWHwE2AXEgAyIuIgQfCwltHiEXICqZBAS7FAsYJCQYCxS6AgWbKiAXIh1tCAsgAyIXFiMEHwwIbR8gFyAqmQUDuxMMGCQkGA4RugIFmyogFxMbEW0HAai6Eg0YJCQYAxy5AgWaKiAXIR5tBg0gAyIuIgMgCQttHiIXHyqZBQS6EwwYJCQXBBy5AwSaKiAXIh1tCAsgAyIuIgQfCgluHyAXIBIYmQYAAP//ADwAAgHHAkQQJwB5AQj/HxAnAHkBCAD5EAYAeeUJ//8AMQG2A0cCzBAmDI8AABAnDI8AzAAAECcMjwGZAAAQBwyPAmUAAP//ADwAAAKWArIQJgB55U8QJwB5AdcATxAnAHkA3f8dEAcAeQDdAWf//wA8AAICmQLFECcAef/l/x8QJwB5Adr/HxAnAHn/5QF3ECcAeQHaAXoQBwB5AN8AVAAA//8APAADAKQDEhAnAHn/5f8gEAcAef/lAccAAP//ADz/OQKWAyAQJwB5AN3+VhAnAHkA3QHVECYAeeUYEAcAeQHXABj//wA8ACkCIAINECcAef/lAMAQJgAOCjMQJwB5/+X/SBAnAHkBYf9IEAcAeQFhAML//wA8//8ApAMgECcAef/lAIgQJwB5/+UB1RAHAHn/5f8cAAD//wA8AAIApAMdECYAeeUFECcAef/lAdIQJwB5/+X/HxAHAHn/5QD9AAIAGgF5AUQDLwAHAA8ASgCwBi+0DAQAEwQrsAkvtAIEABMEKwGwEC+wANa0CgUAEQQrsAoQsQ8BK7QDBQARBCuxEQErsQ8KERKwBjkAsQkMERKxAwA5OTAxEzQgFRQGIyISIhUUMzI2NRoBKkxJlfC2Wi8tAlPc32luAYetrlVbAAAA//8AKgGGAGIDYBAPAEwAAAGGKZkAAgAUAYYBUQMvAAoADQBgALABL7AHM7QNBAATBCuwBTKyAQ0KK7NAAQoJK7INAQors0ANAwkrAbAOL7AK1rALMrQJBQAbBCuwBDKyCQoKK7NACQcJK7IKCQors0AKAQkrsQ8BK7EJChESsAM5ADAxEyM1EzMRMxUjFSM9AQfQvMwuQ0M+gQHqOwEK/vA1ZJmqqgAAAAEAEgF4AUYDLwAeAJMAsAsvtBQEABMEK7IUCwors0AUEQkrsBovtAUEABMEK7IaBQors0AaHAkrsB0ysAIvtB4EABMEKwGwHy+wF9a0CAUAEQQrsSABK7A2Gro/SPZuABUrCrAdLrACLg6wHRCxAwj5BbACELEeCPkDALADLgGzAgMdHi4uLi6wQBqxCBcRErEBADk5ALEaFBESsAg5MDEBFSMHNjMyFhUUBiMiLgMnMxYzMjY1NCYjIgcjNwEuvhImLkJSWEUlORwWBAM4FUkvNTYuMSM0IgMvNHcaTz9DVRYYLA0PRzQuLzco6AAAAAIAGAF4AUcDLwAYACQAbwCwFy+0HwQAEwQrsBkvtBEEABMEK7AKL7AML7QGBAATBCsBsCUvsADWtBwFABsEK7APMrAcELEiASu0FAUAEQQrsAog1hG0CQUAEQQrsSYBK7EKHBEStQYMERcZHyQXOQCxGR8RErIAFA85OTkwMRM0PgMzMhYXIyYjIgYHNjMyFhUUBiMiNyIGFRQWMzI2NTQmGBYhLikWNUQIOA4/MTQBJkM9T1RBmpwqNDUnKDMwAkc4VzEeCjs0QFNOL0w7PlHnMSgpNjQoKzEAAAABABYBhgFHAy8ACQAzALAIL7QJBAATBCsBsAovsATWtAMFABsEK7IDBAors0ADAQkrsQsBKwCxCQgRErABOTAxARUGByM+ATcjNQFHlSQ9GVFS9wMvLLnEaKBtNAAAAAADABYBeAFIAy8AFQAfACoAhACwBS+0JgQAEwQrsCEvtBwEABMEK7AXL7QQBAATBCsBsCsvsAjWtCMFABEEK7ANINYRtBkFABEEK7AjELEpASu0AgUAEQQrsB4g1hG0EwUAEQQrsSwBK7EeGREStgUKEAAgISYkFzkAsSEmERKxCAI5ObAcEbEKADk5sBcSsRMNOTkwMRMWFRQGIyImNTQ3LgE1NDYzMhYVFAYmIgYVFBYyNjU0BiIGFRQWMzI2NTT6TlZDRFVOIxtNPD1MG0pIKytIKyRWNDQqLDQCZSJIOklKOkciFCceMUA/Mh8mhyQfHiUlHR+NLiUmLi4mJQAAAgAXAXgBRgMvABgAJACDALIRAQArtB8EABMEK7AGL7QMBAATBCuwGS+0FwQAEwQrAbAlL7AU1rQcBQARBCuwHBCwCiDWEbQJBQARBCuwCS+0CgUAEQQrsBwQsSIBK7APMrQABQAbBCuxJgErsSIKERK1BgwRFxkfJBc5ALERDBESsAk5sRkfERKyABQPOTk5MDEBFA4DIyImJzMWMzI2NQYjIiY1NDYzMgciBhUUFjMyNjU0JgFGFiEuKRY1RQg5Dj8xNCk/Pk5UQZqbJzMwKCo1NQJfOFYxHgo7NEBTTi9LPD5RLjUoKzIzJyk3AAAAAQARAaoBTQLmAAsAWACwBi+wATO0BwQAEwQrsAAysgYHCiuzQAYECSuyBwYKK7NABwkJKwGwDC+wBNawCDK0AwUAEQQrsAoysgMECiuzQAMBCSuyBAMKK7NABAYJK7ENASsAMDEBFSMVIzUjNTM1MxUBTIYuhoYuAl8uhoYuhoYAAAAAAQALAjABUwJeAAMAKACwAi+0AwQAEwQrtAMEABMEKwGwBC+xAgErtAEFAAcEK7EFASsAMDEBFSE1AVP+uAJeLi4AAP//AAsCBgFTAqQQJgzLANYQBgzLAEYAAAABAG8BIQD9A4QACQAWAAGwCi+wCNa0AwUAEQQrsQsBKwAwMRMzBhAXIy4BNDbZJFlZJDE5OQOEkP6+kUClmqT//wBOASEA3AOEEA8MzQFLBKXAAP//ACcBhgE3AuUQDwBRAAABhimZ//8AGv8rAUQA4RADDMIAAP2yAAD//wBF/zgA5gDhEAMAewAA/bIAAP//ABP/OAFGAOEQAwB0AAD9sgAA//8AEP8qAUIA4RADAHUAAP2wAAD//wAU/zgBUQDhEAMMxAAA/bIAAP//ABL/KgFGAOEQAwzFAAD9sgAA//8AGP8qAUcA4RADDMYAAP2yAAD//wAW/zgBRwDhEAMMxwAA/bIAAP//ABb/KgFIAOEQAwzIAAD9sgAA//8AF/8qAUYA4RADDMkAAP2yAAD//wAR/2UBTQChEAcMygAA/bsAAP//AAz/6QFUABcQBwzLAAH9uQAA//8ADP+xAVQATxAHDMwAAf2rAAD//wBv/tQA/QE3EAcMzQAA/bMAAP//AEz+1gDaATkQDwzNAUkCWsAA//8AFP8xAVUAnxAPAEQAAf9AKZn//wAV/y0BSQCbEA8ASAAC/zwpmf//ABP/LQFIAJsQDwBSAAD/PCmZ//8ABv84AS8AjRAPAFsAAP84KZn//wAT/y4BRwCcEA8B/AAA/z0pmQABACYAAAJRAtsAIwCnALIEAAArtAEEAB8EK7IQAwArtBYEADcEK7IWEAors0AWEwkrtAAhBBANK7QABAAfBCuwABCwBSDWEbQcBAA3BCu0HSAEEA0rtB0EAB8EKwGwJC+wCta0GQUAJgQrsBkQsQQBK7AcMrQBBQAbBCuwIDKyAQQKK7NAAQMJK7NAASMJK7NAAR8JK7ElASuxBBkRErAWObABEbAQOQCxFh0RErEKGTk5MDElFSEVITUiLgI1ND4DMzIXIy4BIyIGFRQWFzUhFSEVMxUBRQEM/q48WS8VDCAwTzKeHUwLNzVBSU5AAUf+//fSkz/gM09RKCBBRjYjoDAoYVZSYgGyP4k/AAAAAAMAJv+pAkEDDAAkACoAMAGxALIAAAArsAMzsR8E6bAlMrIUAwArsBEzsSgE6bAsMgGwMS+wC9a0LwUAPAQrsC8QsSIBK7EjBemwHCDWEbEbBemxMgErsDYauj6x8yEAFSsKDrAHELASwLEGCPmwE8C6PrHzIQAVKwqwAhCwF8CxAQj5sBjABbMAARgTK7ACELMDAhcTK7o+sfMhABUrC7AGELMFBhMTK7AHELMIBxITKwWzEQcSEyuwBhCzFAYTEyu6PrHzIQAVKwuwAhCzFgIXEyuwARCzGQEYEyuzHgEYEysFsx8BGBMrsAIQsyUCFxMruj6x8yEAFSsLsyYCFxMrBbAGELMoBhMTK7o+sfMhABUrC7MpBhMTK7AHELMrBxITKwWzLAcSEyuyCAcSIIogiiMGDhESObArObIFBhMREjmwKTmyJgIXERI5sBY5sh4BGBESObAZOQBAEAECBQYHCBITFhcYGR4mKSsuLi4uLi4uLi4uLi4uLi4uAUAYAAECAwUGBwgREhMUFhcYGR4fJSYoKSssLi4uLi4uLi4uLi4uLi4uLi4uLi4uLi4usEAaAQCxKB8RErIbIiM5OTkwMQUHIzcmJwcjNy4BNTQ+Az8BMwcWFzczBxYXIyYnAz4BNzMCJxMmJwMWJxMOARUUAU8NNw4rIxM3GTw4DiY5XTsINwgsIww3E0IUVAgQaz1DDFUc/HYgLnQiT2lLVRdAQwYSW3w2sFkvX2ZPOAUoKAQQPFw7fi0g/fkJZV/+50wCOxYE/coZSQIEEJ1+iQABACD/6QI5AuUAKQCoALIkAAArsR4E6bIeJAors0AeEgkrsgYDACuxCwTpsgsGCiuzQAsJCSu0FxokBg0rsRcE6QGwKi+wANa0DgUAMQQrsA4QsREBK7EeBem0FAUAJgQrsB4QsSABK7QhBQA8BCuwCSDWEbQIBQA8BCuxKwErsRQRERKwCzmwHhGwJDmwCRKxBhc5ObAgEbEZGjk5ALEaHhESsxEUICEkFzmwFxGxAA45OTAxEzQ+AzMyFyMmIyIGFRQWFxEzFT4BMzIXFQ4BHQE2NzMOASMiLgMgDyg+ZkHPIVIYj1ppPzhNJEMoCxVUVJQXUw2CcUBmPCgPAWQyYmpPNNyKooxmkR8BT187MwNVAkpnZwGzgIYzTmlgAAABACwAAAIeAtkAFQB4ALIGAAArsg8DACuxEgTptAgJBg8NK7ABM7QIBAAfBCuwAzK0DQwGDw0rsAAztA0EAB8EK7ATMgGwFi+wBtaxCg4yMrQFBQA8BCuxABIyMrIFBgors0AFAwkrsBQys0AFEQkrsgYFCiuzQAYICSuwDDKxFwErADAxExUzFSMRIxEjNTM1IzUzESEVIRUzFc7+/lNPT09PAaP+sP4Bi0I3/u4BEjdCNwEXUsU3AAAAAAEAGv/pAhcC2QA5AO4Ash0AACuyGAAAK7QTBABCBCuyLgMAK7E3BOmyNy4KK7NANzQJK7EbGBAgwC+xEATpsBUytCEiGC4NK7AJM7QhBAAfBCuwCzK0JicYLg0rsAQztCYEAB8EK7AGMgGwOi+wK9axAAXpsisACiuzQCsmCSuwITKzJQArCCuxBwXpsAAQsSABK7QMBQAxBCuyDCAKK7NADAYJK7AKMrAMELE1ASuxNAXpsTsBK7ElKxESsh0OKDk5ObEHIBESsgMEGzk5ObE1DBEStQgQExguNyQXObA0EbAVOQCxExsRErIOFh45OTmxNycRErArOTAxExQeARczFSMWFzMVIwYHNjMyFjMyNxcGIyImIyIHJzY3IzUzJicjNTMuATU0NjMyHgMXIyYjIgaTDyYGoIgOAX2GFFk7PyFoGCgrKjlKK4YjNTgwZRJ8gQMUblEiE4llHTU+LB8BWASEQE0CCxwsPg03KBo2MlonHx5COC4lQlc+NiEhNzkxIVt7CR4xVzmaRgAAAAACAEb/pwL6AnIAJgAqAIwAsiYAACuxERgzM7IAAQArsgUBACuwCjO0IQQAQwQrsBYysg0BACsBsCsvsCbWsSUF6bQCBQAmBCuwJRCxGQErsB0ysRgF6bAnMrAYELESASuxEQXpsSwBK7EZJRESsQUcOTmwGBGwBzmwEhKzCwoNKCQXObAREbAMOQCxISYRErUHAhodJygkFzkwMRMzFT4BMzIXPgE/ATMHHgEVESMRNCYnBxUjNQcjEzU0JiMiBhURIwE3DgFGTSJLNGEsI0QwPDc+NThUJyOSVJU3zDMuM0hUAYRZJzECDEovKlAqJAJXWwpJO/53AWkrNQfV+4DZASqYMjdQOf63AUuCDUcAAAUARwAAApMC2QAbAB8AIwAmACkAuwCyCAAAK7ADM7IRAwArsBUztAoLCBENK7IAHCAzMzO0CgQANwQrsgEFJDIyMrQPDggRDSuyGR0iMzMztA8EADcEK7ITFycyMjIBsCovsAjWsQwQMjK0BwUAJgQrsSAnMjKyCAcKK7NACAoJK7AOMrAHELEmASuxFBwyMrQCBQAmBCuxFhoyMrICJgors0ACAQkrsBgysSsBK7EmBxEStQQSHiElKCQXOQCxCggRErAmObERDxESsCk5MDEBFSMVIycjFSM1IzUzNSM1MxEzFzMRMxUzFSMVIzUjFyMzJyMFIxcBMycCkzNdg75OLS0tLVqKuU8zM0+TM++YMmYBTzo6/rFAQAE3RvHx8fFGXUYA//8A//9GXV1dXaNsAVV1AAAAAAIAW//pBNkC2QAHAE4BOgCyRQAAK7I6AAArsDUztA4EAEMEK7AWMrJGAwArsQcE6bJKAQArsAgztD8EACsEK7AJMrIjAQArsSkE6bIpIwors0ApJQkrsko/CiuzQEpNCSu0AEM6TQ0rsQAE6QGwTy+wRdaxRAXpsAAysEQQsQQBK7FKBemwShCxPQErsEsytAsFADwEK7BNMrILPQors0ALCQkrsAsQsSABK7EsBemzEywgCCuxEgXpsBIvsRMF6bAsELEZASuxMgXpsDIQsCUg1hGxJgXpsCYvsSUF6bFQASuxSgQRErA/ObESCxESsQ46OTmwIBGyEDc4OTk5sSwTERKwHjmwJhG1HB0WIy81JBc5sSUZERKwMDkAsQ5FERKwNzmwQxGzEh4uMiQXObAAErEgLDk5sSk/ERKwAzmxByMRErAEOTAxEzMyNjQmKwEFFSMRFBYzMjcmJzMeATMyNjU0Ji8BLgE1NDYzMhcjLgEjIgYVFB8BHgEVFAYjIicVBiMiJjURIw4BKwERIxEhMhYXMzUzFbjCQ0tLQ8ICllYTGw4WGAJYBjVFN0MkLTRZP1lZqwJYAiYwJzFTNlBEdWN6Mj4NMTRDEWlL5V0BLWp0AzxTAYdEeER7RP6ZHBMFKD0vNy0lGx0REyA8O0tVoSwoKyQuHRMcPjhMWj4zCysoAYxET/7LAtlqY5CQ//8AUP/pBHgC2RAnAFYCrQAAEAYANQAAAAcAMgAAAzUC2QAfACMAJwArAC4AMQA0AjEAsgUAACuwATOyDgMAK7QPEhMWFyQXM7QHCAUODSu3CRwgIyQnKCkkFzO0BwQANwQrtwIDBh8sLS8wJBcytAwLBQ4NK7cKGyEiJSYqKyQXM7QMBAA3BCu3DRARFBUYMjMkFzIBsDUvsTYBK7A2GrrBePJeABUrCrAOLg6wLhAFsA4QsQ8R+bAuELEFEfm6PlbxgAAVKwqwEi6xDy4IsC7ADrE0GvkFsAPAusG+8SkAFSsKsAEusQM0CLA0wA6xMRv5BbATwLo+2fPpABUrCrAvLrAXLrAvELEfE/mwFxCxFhP5sDQQswI0ARMrsA4QswYOBRMrswkOBRMrswoOBRMrsw0OBRMrsA8QsxAPLhMrsC4QsxEuEhMrsBMQsxQTMRMrsC8QsxUvFhMrsB8QsxgfFxMrsxsfFxMrsxwfFxMrsC8QsyAvFhMrsyEvFhMrsBMQsyITMRMrsyMTMRMrsC4QsyQuEhMrsyUuEhMrsA8QsyYPLhMrsycPLhMrsAMQsygDNBMrsDQQsyk0ARMrsyo0ARMrsAMQsysDNBMrsC4QsywuEhMrsA8Qsy0PLhMrsBMQszATMRMrsAMQszIDNBMrsDQQszM0ARMrAwCyLjE0Li4uAUArAQIDBQYJCg0ODxAREhMUFRYXGBscHyAhIiMkJSYnKCkqKywtLi8wMTIzNC4uLi4uLi4uLi4uLi4uLi4uLi4uLi4uLi4uLi4uLi4uLi4uLi4uLi4uLi6wQBoAMDEhIycjByMnIzUzJyM1MwMzFzMTMxczEzMHMxUjBzMVIyc3IxchNyMXOwEnIwcjFyUjFwMzJwKYVzmpN1c1aVoURjc4WDOQPFU8kjFYNzVEFFhnQBJzFv7mFnMTk4cWXG4tFQGALRnWOx7x8fFGXUYA//8A//8A//9GXUZGXV1dXV2jaGhoAVF9AAACADwAAAMbAlgADgAcAF8AshkBACuxHATpsAUysAovsBozsQAE6bIACgors0AADAkrAbAdL7Ab1rEaBemwGhCxCwErsQ4F6bAOELEUASuxEwXpsBMQsQQBK7EHBemxHgErALEZABESsQQTOTkwMSU2NzY3AzMDDgEjBREzERMyFhUTIxMuASMhESMRAlY3ERYRAVcBDWpE/q9XQ1RAAVcBASod/vRXTAwNECcBvP46QFEBAXf+1QIMRS3+3QEZFxn99QJXAAAAAAMANgABAhIDHwALACMAJwCuALAmL7QnBAAfBCuwFC+0BgQANwQrsAAvtBoEADcEK7AeL7ANM7QfBAAfBCuwDDKyHh8KK7NAHhAJK7IfHgors0AfIQkrAbAoL7AX1rAmMrQDBQAmBCuwAxCxCQErsRwgMjK0DwUAJgQrsSIkMjKyCQ8KK7NACR4JK7APELQQBQAbBCuwEC+yDxAKK7NADw0JK7EpASuxCQMRErEUGjk5ALEABhESshEXHDk5OTAxASIGFRQWMzI2NTQmNxUjESM1DgEjIiY1NDYzMhc1IzUzNTMVExUhNQENPktMPjtIR8g2Qx9GMV9ublxfMk5OSwP+VwIuZVJTZGNSVWTIP/3YPiwnindxiEmMPykp/Uo/PwAAAAABACT/6QJrAsUAMABzALIAAAArsSsE6bIWAgArsRwE6bQHCAAWDSuwJTO0BwQAHwQrsCcytA8OABYNK7AhM7QPBAAfBCuwHzIBsDEvsAvWsSQF6bEyASuxJAsRErEGEDk5ALErABESsC85sAcRsC45sRwPERKwGTmwFhGwGDkwMQUiLgMnIzczJjU0NyM3Mz4EMzIXBy4BIyIGByEHIQYUFyEHIx4BMzI2NxUGAaQ+Z0AvFQRTFjcBA08WPwMTL0BsQGNeHjNLLERzGAFFF/7JAgEBHxj/FnhEKUU5RxctQVE9GTsQEAUdOxU5UUEvQ0kmGmRfOxUeDztcaxQiWSsAAQAYAAACkgLZABQATACyAgAAK7ARM7IHAwArsAsztAUEAgcNK7EPEzMztAUEADcEK7EJDTIyAbAVL7AC1rAGMrEBBemwCDKyAgEKK7NAAgQJK7EWASsAMDETFSMRIzUzETMRMwEzATMVIxMjAyOsXTc3XUYBJXj+1+y5+W73GQD//wFnSAEq/tYBKv7WSP6ZAWcAAAEAFQAAAlEC2QAXAEQAsgQAACuyDwMAK7EOBOmwETIBsBgvsATWsQgMMjKxAwXpsRIWMjKyAwQKK7NAAxEJK7IEAwors0AEDgkrsRkBKwAwMQEVBxUjNQc1NzUHNTc1IzUhFSMVNxUHFQHykF2Tk5OT8AI875CQAZlGXfa5X0ZfZl9GX9xSUp9dRl1mAAAA//8ADv84BNwC2RAnA1QCvAAAEAYDKAAAAAIAIv84AicC1wAMADMAgQCyFQAAK7ATM7AzL7ENBOmwBS+xKATpAbA0L7Al1rEIBemwCBCxEAErsTAF6bIQMAors0AQMwkrsBAQsAIg1hGxKwXpsTUBK7EIJRESsxMYGh4kFzmwAhGyEhsoOTk5sBASsC05ALEVDRESsRAwOTmwBRG3AgAIEhQlKy0kFzkwMQE2NTQmIyIGFRQeAgMyNjU0JwcnByMTFz4BNy4INTQ2MzIWFRQHHgEVFAYjAWI1HRQaKAwPGwIoR2hxOydqhUMIJQ8DGgYWBg8FCANaSzpQW0RHfVIBp1xGGh4oGw8lHjP92S4idJTqc3MBUHUQQB8FLgwoDyETGxcLS1tKOGWkY6ZhTV0AAAAEACcAAAKaAtkABAAhACYALQCkALIUAAArsh0DACuxJgTptBIAFB0NK7ESBOm0FxYUHQ0rsQMNMzO0FwQAEwQrsQsoMjK0GxoUHQ0rsQYnMzO0GwQAEwQrsQUiMjIBsC4vsBTWsRgcMjKxEwXpsgAiJzIyMrIUEwors0AUFgkrsBoysBMQsSsBK7ApMrEJBemyCSsKK7NACQ0JK7AFMrEvASuxKxMRErEDIzk5sAkRsQ4hOTkAMDETMzI3ISUVIxYVFAczFSMOASsBESMRIzUzNSM1MzUhMhYXKQEmKwEdASE2NTQnuMJRJf7IAeI0AwEyPBVmRuVdNDQ0NAEtUWwW/l0BMyVMwgFNAwQBhzGkMBQVDg0wPUb+ywG4MEQwfUA9K1tEDxAUEQAAAAACAFr/owKTAyAAIgArAMsAshMAACuyFgAAK7EKBOmwKzKyFgoKK7NAFhgJK7IZAAArsgIDACuwIjOxCQTpsCMysgIJCiuzQAIACSu0DxAYAA0rsQ8E6QGwLC+wHNa0JgUAPAQrsCYQsRgBK7EAIzIytBcFABsEK7EBCTIysBcQsQ0BK7QRBQAbBCuyDREKK7NADQ8JK7ARELAFINYRsQYF6bAGL7EFBemwERC0EwUAEQQrsBMvsS0BK7ETDRESsBQ5ALEPChESsBQ5sBARsRwmOTmwCRKwBTkwMQEzFR4BFyMuAScRPgE9ASM1MxEjJwYHFSM1LgE1ND4DNxUOARUUHgIXAV88Y30QVAxSPkJsdb8yFDp4PHSRDiY5XTtSYBElSjIDIDwFemlBTwb9qgmMShRS/nthaAtHRwzRni1bZFA6CFQQnncsWVpCCgAAAAADABEAAAKNAtkAFwAbAB4ASwCyCAAAK7ADM7IRAwArtAoLCBENK7EAGDMzsQoE6bEBBTIytA8OCBENK7EVGjMzsQ8E6bETHDIyAbAfL7EgASsAsREPERKwHjkwMQEVIxcjJyEHIzcjNTM3IzUzEzMTMxUjFyEzJyM3MycCcjJNaEv+501jTjhUIXWRXXhciW4h/rPoH6gccjcBKU7b29vbTlxOAQb++k5cXE6iAAAAAAEAW//pAkMC5QA6APAAsgoAACuxAATpsgAKCiuzQAAECSuyJwMAK7EgBOm0ExQKJw0rsDEztBMEABMEK7AzMrQaGQonDSuwLTO0GgQAEwQrsCsysyQKJwgrsB0zAbA7L7AQ1rETGTIytDYFADwEK7A2ELAjINYRtCQFACYEK7AkL7QjBQAmBCuwNhCxHQErtCkFADwEK7IpHQors0ApMwkrsCwysCkQsAQg1hG0AwUAJgQrsAMvtAQFACYEK7E8ASuxJBARErASObA2EbAVObEdIxEStwAKGxggJzE0JBc5sSkDERKxKy45OQCxEwARErAQObEkGhESsCk5MDElMjY1MxQOAyMiLgM1NDcjNTM2PwEjNSE2NTQmIyIGFSM0NjMyFRQHMxUjBg8BMxUhBhUUHgIBSFNYTx8wQ0AjOFc0Ig0RETUgL0zQAVkoSD5HUE94a9wLFjUdMkrO/qg0DiBAO1ZAN1QyIAsbKzw8IS8mMx4PGDMbOThDRzVfa9YoHzMeEBczIT0WKioaAAIAIf+CAloDAgAeACQAnwCyHgAAK7ACM7EXBOmwHzKyHhcKK7NAHgEJK7IXHgors0AXGwkrsCAvsBYzsQwE6bAPMrIgDAors0AgEwkrsgwgCiuzQAwNCSsBsCUvsATWsSMF6bAjELEBASuxDB8yMrQABQARBCuxDhYyMrAAELEaASuxGwXpsBMg1hGxEgXpsSYBK7EjBBESsAY5ALEgFxESsQQVOTmwDBGwCzkwMQUjNSQRND4FNzUzFR4BFyMuAScRPgE3Mw4BBycRDgEVEAFiO/76BQ4XKDZOMDtsaBVfDzhDTD0PYBBveTtZUH5oFgFkIj1IOzsqHQQ2NARgc0c5BP3ABERhiG4FVAI+CYiF/vEAAAIAIAAAAeQC2QADAAsASwCyCQAAK7IBAwArsQAE6bQECwkBDSuwBjOxBATpAbAML7AJ1rEIBemyCAkKK7NACAYJK7ACMrIJCAors0AJCwkrsAAysQ0BKwAwMRM1IRUFIRUjESMRIyABxP48AcSzXbQCh1JSUlL+HQHjAAABAAz/+QHnAtkAJwCOALIJAAArsiADACu0HwQAQwQrsCIytAMXCSANK7QDBABDBCu0HBsJIA0rsCYztBwEAEMEK7AkMgGwKC+wGdawHTK0AAUAGwQrsCMysgAZCiuzQAAmCSuwITKyGQAKK7NAGRsJK7AfMrEpASuxABkRErAJOQCxAwkRErEIDzk5sBcRsBE5sBsSsRMUOTkwMQEUBiMiJx4BFwcuCCc3FxYzMj0BITUhNSE1IRUjFTMVIwGESzYJFDp5EDMTICMWJxMxFEAPOx8dSj7+0QEv/tEB22NjYwGSM0ICVJMJNhMiKRo0GUUeXRUpLSkuWElbSUlbSQAAAf34Ai7/7gLsAAcAEgCwAi+0BwQAEwQrAbAILwAwMQMVITY3FwYHEv4KWl4XTyACUyRNcBdiIAAB/fgCLv/uAuwABwASALAHL7QABAATBCsBsAgvADAxASEmJzcWFyH9+AGWIE8XX1n+CgJTIGIXcE0AAAAB/zb/8v9tAqQAAwAeALIAAAArAbAEL7AA1rQDBQARBCu0AwUAEQQrADAxBxEzEco3DgKy/U4AAAH/Hf///1kCFwADACMAsgAAACuyAQEAKwGwBC+wANa0AwUAGwQrtAMFABsEKwAwMQcRMxHjPAECGP3oAAH9jQH3AAADIAAWABIAsAQvtBQEABMEKwGwFy8AMDERBy4BIyIGBxYXByYnNjcXBgc+ATMyFhc2lUQ9ljAneghjgCQUHxYJNJtHTaUCaRwyNzwqCi8gJB96bAmFIys9OwAAAAAB/Y0B9wAAAyAAFgASALATL7QDBAATBCsBsBcvADAxAT4BMzIWFyYnNxYXBgcnNjcuASMiBgf9jTOlTUebNAkWHxQkgGMIeicwlj1ElTYCaTM7PSsjhQlseh8kIC8KKjw3MgAAAf2nAiL/9wN5AAwAHACyDAMAK7QCBAATBCsBsA0vALEMAhESsAc5MDEDFSEWFwcmJzY3FwYHCf37IE8XQWJiQRdPIALgJCBiF01eXk0XYiAAAAD///2nAiL/9wN5EA8NAv2eBZzAAAAC/ncAbf+dAZIACQAUAEoAsA0vtAEEADcEK7AGL7QTBAA3BCsBsBUvsBDWtAgFABsEK7AIELEDASu0CgUAGwQrsQMIERKyDRITOTk5ALEGARESsQoQOTkwMSQyNjU0JiIGFRQ3FAYjIiY1NDYyFv7tOi0qQCveWDs8V1d4V7UtHR8sLR4dHT1VWDo8V1UAAAAC/ncAbf+/AbgADgAeAGEAsA0vtA8EADcEK7AZL7QDBAA3BCsBsB8vsADWtBwFABsEK7AcELESASu0CgUAGwQrsRIcERKzBQwNAyQXObAKEbEGCDk5ALEZDxEStAAKEhccJBc5sAMRsgcIBTk5OTAxJTQ2MzIXNxcHFhUUBiImFzI2NTQnByc3JiMiBhUUFv54VzwnITkzOBVTf1KRHysDFTMUCgkdLCf+QFQUOTM3Iyo8V1YOKSELCxQzEwMrIB0tAAD///53AEn/wgGREIcNBf4KAAkAAMAAQAAAAAAA///+KQIcAAEChBAnAHn90gE5ECcAef6JATkQBwB5/0IBOQAA///9rwJGAAwCrxAjAGr+2P/iEAMAav2W/+MAAP///Sz/NwEUAx8QBw+Y/SIAAAAAAAL9Mf8/AQ4DHAADAAcANACwAS+0BwQAEwQrsAYvtAIEABMEKwGwCC+wAda0BwUAEQQrsAcQsQQBK7QABQARBCsAMDEFIREhAxEhEQEO/CMD3S78f8ED3fxRA4H8fwAAAAL9NP9CAQ4DHAADAAcAAAcJBt8Bqv5W/lcBqf4TAe0B7XoBqQGp/lf+EwHtAe3+EwAAAAAD/TL/OgEOAxYABwATABsAUACyAwMAK7QIBAATBCuwDi+0GgQAEwQrAbAcL7AR1rQXBQARBCuwFxCxAAErtAsFABEEK7EAFxESswUIDhQkFzkAsQMaERKzBgsRFSQXOTAxEzQmIyIHATYBMgAVFAAjIgA1NAAJAQYVFBYzMt30yLF4AoBl/kTnAQb+9uXk/vcBDgIG/YJl9civASjP7mf9gXcCoP7y4Nf+6QEY1twBEvy4AoB4rsX4AAAAAAH9dgIqAAEDgQAhAB4AshICACu0AAQAEwQrAbAiLwCxABIRErEJGjk5MDEBIS4BJzceAhcOAgcnPgE3IR4BFwcuAic+AjcXDgH9wQH0KiQhGCMfPSMjPR8jGCEkKv4MKiQhGCMePiMjPh4jGCEkAucsKy4VKiM/Hx8/IyoVLSwsLCwtFSojPx8fPyMqFS4rAAL7cv9u//8DVAACAAUAEgCwBC+0AgQANwQrAbAGLwAwMQcJAQUhAYX+Pv48BAr7cwJHSgL//QFIA+YAAAH9Q//D//MC7QADAAAJASMB/Y8CZEz9nALt/NYDKgD///7B//L/dQKkEAcN3f57AAAAAAAB/lAAWgBIAn4ABQAyALAEL7QFBAA3BCuyBAUKK7NABAIJKwGwBi+wAta0AQUAGwQrsgIBCiuzQAIECSsAMDETESMRITVISP5QAn793AHcSAAAAP///in/XwAB/8cQJwB5/dL+fBAnAHn+if58EAcAef9C/nwAAAAB/jAB9wAAAq8ABwA+ALADL7AGM7QEBAALBCuwBBC0AQQANwQrtAMEAAsEKwGwCC+wA9a0AgUAGwQrsAIQsQcBK7QGBQAbBCsAMDEDIRUjNSEVI0f+v0gB0EcCZ3C4uAAB/EIAFP/QAiIADAAaALACL7QMBAAfBCsBsA0vALEMAhESsAc5MDEDFSEWFwcmJzY3FwYHMPzlMnkjZJeXZCN5MgE3ODGXI3eQkHcjlzEAAAL9rv+dAEoCTwADAAcAABMBIwEjASMBSv4+RwHFT/4+RwHFAk/9TgKy/U4CsgAA///9+/8L//H/yRAPDP396QH3wAD///34/w7/7v/MEA8M/P3mAfrAAP///bb+4gAG/+QQRw0CAA/9SUAAMAAAAP///af+4P/3/+IQRw0C/Z4Be8AA0AAAAAAB/tMCNv+YAvIADgA2ALINAgArsAMzsAkvsAcztAAEAAsEKwGwDy+wDta0AgUAEQQrALENCREStQQGAgoMDiQXOTAxAzMHNxcHFwcnByc3JzcX3ykDRQxGLSEoKSEtRgxFAvJJGScTOhg9PRg6EycZAAAAAAQAKf/sAzMC5QADADQAQQBmAVQAsl8AACuwAjO0VgQAHwQrslZfCiuzQFZZCSuyAAMAK7IKAwArtAQEAB8EK7IECgors0AEBwkrtCY+XwoNK7EUQjMztCYEABMEK7AXMgGwZy+wKda0OwUAGwQrswc7KQgrtAYFABsEK7A7ELEyASuwLzK0DQUAGwQrsA8ysA0QsWQBK7RTBQAbBCuwUxCxSgErtEUFABsEK7FoASuwNhq6PprysQAVKwoEsA8uDrAQwLEwHPmwQcAEsEEQsy9BMBMruj6l8uQAFSsLszVBMBMrsjVBMCCKIIojBg4REjkAtQ8QLzA1QS4uLi4uLgGzEDA1QS4uLi6wQBoBsQY7ERKxAyY5ObAyEbcCCgQdLBs3PiQXObANErEWGTk5sUpTERK1AEJNVlhfJBc5sEURsQFZOTkAsSZWERKyRU1kOTk5sD4RsB05sAQStQ0SGykyOyQXOTAxATMBIxMiByM+ATMyFhUUDwEGFRQzMjcHBiMiNRQOCCMiJjU0Njc+AT8BNjU0JhcOBBUUFjMyNjcFMhYVFAcjNjU0JiMiDgMVFBYzMjczDgQjIi4CNTQ2Aus6/Y46jk4VPApaSzhFBC4BGwYGCRoMNwsFDQkRDRQUGA0wN05dSS4EAgEsGRNANDMdIh4wUQcBhThFAj0BJyIjNx4UBiwlUCE9BQkdI0EpJjgcDHkC2f0TAsFDPD4tJAcU2QIFFQIvBzgBCQQKBQkFBwMDMSwwTA0JERUNCQUTG5MHCgkQIxoXGTIhUj4sEg0GCR8kIzE8KxAqMVsTFzIeGR0tLBVzlwAEACn/7AM+AuUAMAA9AEEAeQG8ALJcAAArsEAztGcEAB8EK7I+AwArsgYDACu0AAQAHwQrsgAGCiuzQAADCSu0IjpcBg0rsRBFMzO0IgQAEwQrsBMyAbB6L7Al1rQ3BQAbBCuzAzclCCu0AgUAGwQrsDcQsS4BK7ArMrQJBQAbBCuwCzKwCRCxXwErtGQFABsEK7NCZF8IK7RTBQAbBCuwZBCxbAErtFkFABsEK7BNINYRtEgFABsEK7F7ASuwNhq6PprysQAVKwoEsAsuDrAMwLEsHPmwPcC68HrB6QAVKwoOsHcQsHPAsVUd+bBWwASwPRCzKz0sEyu6PqXy5AAVKwuzMT0sEyu678rCFgAVKwuwdxCzdHdzEyuzdXdzEyuzdndzEyuyMT0sERI5snZ3cyCKIIojBg4REjmwdDmwdTkAQA0LDCssMT1VVnZ3c3R1Li4uLi4uLi4uLi4uLgFACwwsMT1VVnZ3c3R1Li4uLi4uLi4uLi6wQBoBsQI3ERKxIkE5ObAuEbcGABkoFzM6QCQXObAJErESFTk5sWxTERK0RVBcZ3EkFzkAsSJnERK1QkhQWV9hJBc5sDoRsBk5sAAStQkOFyUuNyQXOTAxASIHIz4BMzIWFRQPAQYVFDMyNwcGIyI1FA4IIyImNTQ2Nz4BPwE2NTQmFw4EFRQWMzI2NwEzASMBNDYzMhYVFAcjNDU0JiMiBhUUHwEeARUUBiMiJjU0NzMGFRQWMzI+AjU0LgcxJy4BAQdOFTwKWks4RQQuARsGBgkaDDcLBQ0JEQ0UFBgNMDdOXUkuBAIBLBkTQDQzHSIeMFEHAdM6/Y46AX9dSjVBBDwiICkzPTcvKGFQP0cEQAEoJh4sFAkDBQUJBQoECjU4KwKtQzw+LSQHFNkCBRUCLwc4AQkECgUJBQcDAzEsMEwNCREVDQkFExuTBwoJECMaFxkyIQED/RMBDDtRLyYNEgYKFRgoHRwPDgsmIUFNMSwQFA4EGxwRGRQHBQkHBgUDBAECDg8lAAACADD/6QKlAuUAHAAhAHUAshcAACuxEQTpshEXCiuzQBEUCSuyBgMAK7EMBOmyDAYKK7NADAkJKwGwIi+wANaxIAXpsCAQsR0BK7QPBQARBCuwDxCxFAErsRUF6bAJINYRsQgF6bEjASuxCQ8RErIGERc5OTkAsQwRERKyAB0eOTk5MDETND4DMzIXIy4BIyIHERYzMjY3MwIhIi4DFxEGFRQwETBHeUzuK18QXlc2Ky86WmARYCH+9Ut3Ry8Rqk0BZDJiak807k5OFv3WGGVq/t8zTmlgtgHXUZ6XAAAA//8AHv/pA8kC5RAiAHKHABADACYBLAAAAAIAMwABAgMCrQAlACwAlwCyJwEAK7ARM7QFBAArBCuyBScKK7NABQYJK7AgL7QdBAArBCuwIS+0JgQAKwQrsBIyAbAtL7AA1rQqBQAbBCuwKhCxIQErsQUmMjK0HQUAGwQrsQcRMjKyHSEKK7NAHR8JK7AdELEXASu0GQUAJgQrsAwg1hG0CwUAJgQrsS4BKwCxJiERErAcObAnEbMLGBkqJBc5MDETND4CNzUzFR4BFyMuAycRPgQ3Mw4BBxUzFSE1LgMXEQ4BFRQWNBAlRzFKQz4MSwMGDhkSERsOCwMCSwlDSdj+3jFHJRCtLzQ1AW4kR0kzB1BQC1FDDxMcFQX+tQYZFyYMD09iC0FDgwYzR0eCAU8LWEZDVwAABAAw/+wC/QLlAAMAKAA6AEwAvACyMgAAK7ACM7Q7BAAfBCuyAAMAK7IEAwArtA8EAB8EK7QYIQIEDSuwRDO0GAQAHwQrsCkyshghCiuzQBgbCSsBsE0vsCbWtBUFABsEK7AVELEMASu0BwUAGwQrsAcQsTUBK7RKBQAbBCuwShCxQQErtCwFABsEK7FOASuxFSYRErADObAMEbUCBA8YGiEkFzmwBxKwGzmxQUoRErEAKTk5ALEhOxESsSw1OTmxDxgRErQHDBUJJiQXOTAxATMBIxMyFhUUByM2NTQmIyIOAxUUFjMyNzMOBCMiLgI1NDYBMhYVFA4DIyImNTQ+AwMyPgM1NCYjIg4DFRQWAqw6/Y460jhFAj0BJyIjNx4UBiwlUCE9BQkdI0EpJjgcDHkByD9MDB8vUTI9SwsfL1AXIzgeFAYsKCM3HhQGLALZ/RMC+D4sCRYGCR8kIzE8KxAqMVsTFzIeGR0tLBVzl/6gSzwbQUw9KUs8HEBMPSn+oyIwPCsQLDEjMDwqECsyAAMAMP/sAygC5QADACgAPwFBALIqAAArsCkzsi0AACuwAjO0OgQAEwQrsjotCiuzQDozCSuyND4/MjIysgADACuyBAMAK7QPBAAfBCu0GCEtBA0rtBgEAB8EK7IYIQors0AYGwkrAbBAL7Am1rQVBQAbBCuwFRCxDAErtAcFABsEK7AHELEwASuwMjK0NwUAGwQrsDUysUEBK7A2Gro+mfKtABUrCgSwMi4FsDPABLE1HPkFsDTAuj6h8tEAFSsKsCousD8usCoQsSkI+bA/ELE+CPm6PszzqAAVKwuwKhCzKyo+EyuzPSo+EyuyKyo+IIogiiMGDhESObA9OQCzKzI1PS4uLi4BtykqKzM0PT4/Li4uLi4uLi6wQBoBsRUmERKwAzmwDBG1AgQPGBohJBc5sAcSsBs5ALEhOhESsTA3OTmxDxgRErQHDBUJJiQXOTAxATMBIxMyFhUUByM2NTQmIyIOAxUUFjMyNzMOBCMiLgI1NDYBIzcGIyImNTQ3EzMDBhUUFjMyNj8BMwKqOv2OOtQ4RQI9ASciIzceFAYsJVAhPQUJHSNBKSY4HAx5Ai43CTxPLzUDPT05AiMdLkYNLT0C2f0TAvg+LA0SBgkfJCMxPCsQKjFbExcyHhkdLSwVc5f9HCk6KiUOCgEj/vULCBoeRjrW//8AKP/pAmUC5RAGAVIAAAABACv/6QKgAuUAJACjALIaAAArsSAE6bIgGgors0AgHAkrsg4DACuxCATpsggOCiuzQAgMCSu0BCQaDg0rsQQE6bIkBAors0AkAQkrsgQkCiuzQAQCCSsBsCUvsBzWsR0F6bAdELALINYRsQwF6bAML7ELBemwHRCxAQErtAAFADwEK7ADMrAAELEjASuwBTKxFAXpsSYBK7EjABESswgOGiAkFzkAsQQkERKwFDkwMQEjNTMVMy4BIyIGByM2MzIeAxUUDgMjIAMzHgEzMjY3IwFLUlL1DHheV14QXyvuTHlHMBERL0d3S/71IWARYFpnfwb3AQ7OPnOCTk7uNE9qYjIxYGlOMwEhamWTfgAA//8AKAAAA28C2RAiAHKRABADACkBNgAAAAIAA//qBLoCzQB0AH0BawCyOwAAK7RNBAATBCuyLgAAK7QiBAATBCuyFgIAK7R1BAATBCuyDgIAK7RGQTsWDSu0RgQAQwQrtBI1OxYNK7AdM7QSBAATBCuweDK0BV87Fg0rtAUEABMEK7FyFhAgwC+0ZwQAEwQrsmdyCiuzQGdsCSsBsH4vsD7WtEoFABEEK7JKPgorswBKQwkrsEoQsWUBK7QABQARBCuzAwBlCCu0YgUAEQQrsGIvtAMFABEEK7AAELExASu0IAUAGwQrsiAxCiuzACAqCSuwIBCxfAErtBgFABEEK7F/ASuxYkoRErU7T1NYam8kFzmwZRGyUGdyOTk5sQADERKyBVFfOTk5sDERsFw5sCASshI3XTk5ObB8EbYIExYdDzR4JBc5ALFGIhESsiA+Sjk5ObBBEbQnJSoxSCQXObA1ErNPUVVYJBc5sBIRsRxcOTmwXxKweTmxZwURErQACF1ibyQXObF1chESsRh8OTkwMQEUBhUUMzI2PwE2Mh4CFRQHAzM+ATMyFRQHDgEPAQYVFDMyNjc2OwEyFRQOASMiJjU0PwEjIg8BDgEjIiY1NDYzMhUUBiMiJwYVFBYzMjc2NwYHBiMuATU0NzY/AQYjIiY1NDY1NCMiBgcGKwEiNTQ2MzIWJSIGBzY3NjU0AgUhFCdcJpkDBgQBAwLkgGrDYUcxNK50SWM5I1UoAgULCDxeJDo5TEA8Lhd5QcNQOUswIyEkFBMLCT80ZJYrSJ9cAwsECQJW0kozLh4pJRkaNCQEAwsIaSchJgJqM5Zi3FAwAkAVNwcQMyWVAwMDBwEFA/7Vj6lANkZJPwdmjUUzSzgDCApGRDYwVGtZAahbiCkmIEAiDhkPEw8eH9c+WRNrBAEFAwIDeRRXFxUUDjkSFzYzBAkPax1VmYUScEQrLQAAAAABABH/kQJPAs4AaQDKALAzL7QuBAATBCuwUy+0WgQAHwQrslpTCiuzQFpXCSuwRy+xFwTpsAgvsQAE6QGwai+wYNa0CwUAEQQrsAsQsV0BK7RNBQARBCuzNk1dCCu0KwUAEQQrsE0QsUQBK7QaBQAmBCuxawErsQtgERKwWjmxNl0RErARObArEbBKObFETRESQAsACBchAyguMTM8RyQXOQCxUy4RErQoITAxNiQXObBaEbI+QlU5OTmwRxK1GhFEPE1gJBc5sBcRsAs5sAgSsQUGOTkwMQEyNxcOAQcmIyIGFRQeAxU3PgMzMhYVFA4CBwYHJic2NTQmIyIGFRQWMzI3FwYjIiY1ND4DNx4EMzI1NCYjIgYHHgEVFA4DIyInNjMyFjMyNjU0JjU0PgQ3PgEBNTgWEhBBCxcmIzAFCwYRKhQXLTAbTWUUNCgsNgcJBgcjGCArGhYaIwgkISAmGx84GhkCCwYMDwpRYEsgTgkLEh0oMiQNJR1EBgQwDw4ZUggKFAkXASsnArMbDBlXEBssIQsXHA0eAS0VFiIQknApRUcsLDYGBwgKCxUbMCMcIhcVGTAoHDQgJA0MBRwKEgbBW24/FBFBHzFNKx0JGFMrJBohnTcWKRwhDhwBOBcAAAAAAwAuAAACWQLZAAsADwATAHUAsgkAACuwBDO0DgQAHwQrsBEysgoDACuwAjO0DQQAHwQrsBAytAAHCQoNK7EABOkBsBQvsAnWtA4FABEEK7AOELEPASu0CAUAEQQrsAAysAgQsQEBK7AFMrQQBQARBCuwEBCxEgErtAQFABEEK7EVASsAMDETMxEzESMRIxEjETMHIxEzAREzEeS/tra/trY3SEgBLUgBngE7/ScBTP60Atk2/ZMCbf2TAm0AAAAAAQAcAAACFALZABcAxACyFwAAK7ILDBYzMzOyAAMAK7ABM7IFAQArtBIEADcEKwGwGC+wD9awDTKxCAXpsAoysRkBK7A2Gro+n/LIABUrCrAXLrABLrAXELEWBPmwARCxAAT5uj6Z8q4AFSsKBLANLgWwDMAEsQoE+QWwC8C6PprysQAVKwuwFhCzAhYBEyuzFRYBEyuyFRYBIIogiiMGDhESObACOQCzAgoNFS4uLi4BtwABAgsMFRYXLi4uLi4uLi6wQBoBALESFxESsAg5MDETMwM+ATMyFhUUBwMjEzY1NCYjIgYHAyO3VDkvVDg/SARQVEkGLyZEZBE9VALZ/vIsJEM7FBH+iAFXGwwmL2BS/t8AAQBWAAACTgLZAB8BBQCyGAAAK7IMDRczMzOyHQMAK7AeM7IAAgArsgYBACu0EwQANwQrAbAgL7AQ1rAOMrEJBemwCzKxIQErsDYauj6f8sgAFSsKsBgusB4usBgQsRcE+bAeELEdBPm6PpnyrgAVKwoEsA4uBbANwASxCwT5BbAMwLo+mvKxABUrC7AXELMCFx4TK7MDFx4TK7MWFx4TK7AYELMZGB0TK7AXELMfFx4TK7IZGB0giiCKIwYOERI5shYXHhESObADObACObAfOQC2AgMLDhYZHy4uLi4uLi4BQAsCAwwNFhcYGR0eHy4uLi4uLi4uLi4usEAaAQCxExgRErAJObEABhESsRocOTkwMQEPAj4BMzIWFRQHAyMTNjU0JiMiBgcDIxMHPwIzBwGPD1UfL1Q4P0gEUFRJBi8mRGQRPVR6Vg9XEVQLAsNIHZMsJEM7FBH+iAFXHAsmL2BS/t8CPx5IHlIzAAIACP/vA4YCzQAQAE0A6QCySwAAK7QeBAATBCuwGS+0FAQAQwQrsCIvsEcztAIEABMEK7A6MgGwTi+wEda0HAUAEQQrshwRCiuzABwWCSuwHBCxJAErtAAFABEEK7AAELE9ASu0RAUAEQQrsU8BK7A2GroTLMLwABUrCg6wKBCwKsCxCh75sAjAswkKCBMrsCgQsykoKhMrsikoKiCKIIojBg4REjmyCQoIERI5ALUICQooKSouLi4uLi4BtQgJCigpKi4uLi4uLrBAGgGxJBwRErEeSzk5sT0AERK0BCI5OkckFzkAsRkeERKxERw5ObAUEbAaOTAxARQXPgQ3DgUHBgE0NjMyFRQGIicGFRQzMjY/ASY1NDc+Azc2MzIXFBYVFAcOBAc+ATU0JzQ7ATIVFAYPAQ4BIyImAY8+FksoRE80EF8nTSozEjz+eS8jISQoCQh2P549EV41JnhtozUBAgYCAgNMdEcpKAhIcQIOAgqNURI73Vw6TgFVOxUheTpVRSMFHg4gGywZVP6rHj8iDhkPDxA6e1YYHFdBTDZHHiwWAQYBCAIGATBpZUtbEA54RwgQDCpXfAwcXIIoAAACAA//qQJPArsAHgA4AL0AsBsvsQME6bMGAxsIK7EYBOmyGAYKK7NAGAAJK7AuL7EoBOmyLigKK7NALh8JK7IoLgors0AoKgkrsDMvsSIE6QGwOS+wH9axOAXpswA4HwgrsR4F6bA4ELELASuxEgXpsAgg1hGxFQXpsBIQsSoBK7ErBemxOgErsQseERK1BhgDIjEzJBc5sRIIERKxDiY5ObAVEbEoLjk5sCoSsA85ALEuAxESsggOFTk5ObAoEbAxObEiMxESsCY5MDEXNDYzMhYzMjU0JjU0NjczDgEVFBYVFAYjIiYjIgYVAzQ2MzIeAzMyNzMUBiMiLgIjIg4CFUJUNR02FDkiGRtaIBInWUQYMREcHI5gYDFKKB8hEzAGVE8+JkInOx8XIiMTVz9aNH8VZBpBSiMrP0cYYRdagDQZJQIJjnsXICEXPy5sIykjCyFKOAAAAAMAKf/vA18C4gBEAE0AVwE4ALI3AAArsDIztEoEAEMEK7I3AAArsSkE6bIYAwArsAoztE4EADYEK7RFPDcYDSuxRQTptEITNxgNK7AVM7RCBAA3BCuwQDIBsFgvsDnWtEgFAC8EK7BIELEAASuxEAXpsBAQsVUBK7EbBemxWQErsDYaujzt7GcAFSsKsEAuDrAWwLEjEvmwUsAFsEAQsxVAFhMruj2U7o8AFSsLsCMQsyEjUhMrsyIjUhMrsiIjUiCKIIojBg4REjmwITkAs1IhIiMuLi4uAbUVQFIhIiMuLi4uLi6wQBoBsRAAERKzNzxFSiQXObBVEUALCgsYICcrMjQ+QkwkFzmwGxKwLDkAsUo3ERKwNDmxRSkRErMnOUhMJBc5sDwRsiwrPjk5ObETQhESsCA5sE4RshAAGzk5ObAYErALOTAxEzQ+BTc2NxcOAxUUFjMyNz4BMzIWFRQOAgcOBQcWMzI3Fw4EIyInDgEjIjU0NjMyFzY3BiMiJhMiBhUUMzI3JgEiDgEHPgE1NCbWFhs3HkIMHAcDFzQ2OhdFSQ4eRF1JQU4aPntXAxAIEQ4UDDYxQDZLCBMnKkAjVkMcdzCvZ1hAZBwpChtbewQfJ0QsRD4BxhElNRpWYBYB4SI+LC0WHwUKAwFFGh8uNCEqMwLQizc0MFhaQg0KORoxHyYQH3EbEyQzJRsyFxtiLFA7JYYBY/7cGwwcIyACCSZxWBF6MRoZAAACAB//9QHGAtYAJAAtASIAsg0AACuxCATpsCgvsSIE6QGwLi+wENawETKxBgXpsAUysAYQsSUBK7QABQAxBCuxLwErsDYauj2j7sYAFSsKBLARLg6wHMAEsQUN+Q6wKsCzAwUqEyuzBAUqEyuwERCzEhEcEyuzExEcEyuzFBEcEyuzFREcEyuzGREcEyuzGhEcEyuzGxEcEyuwBRCzKwUqEyuyEhEcIIogiiMGDhESObATObAUObAVObAZObAaObAbObIEBSoREjmwAzmwKzkAQA4VKisDBAUREhMUGRobHC4uLi4uLi4uLi4uLi4uAUAMFSorAwQSExQZGhscLi4uLi4uLi4uLi4usEAaAbEGEBESsBg5sCURswILDSIkFzkAsSgIERK0AAoLEBYkFzkwMQEUBw4CFRQzMjcXBiMiJjU0PgI3Byc3PggzMhYHNCYjIg8BPgEBxu4MHgseLyk9QGsvNQsLFQM0Im8IFg0UDxYWHSMVNjNQDBMhIyFFPwJYdKApYSkNQk4cfzswDjInQgwpOUwcUy5BIy0XFwlLORkVdmw/UQAAAgAF/+kCygLZAB4AKQCnALITAAArsA4zsgsAACuxJATpshgDACuwHDOyBQEAK7EfBOm0FhUfGA0rsQEQMzO0FgQAEwQrsQAaMjIBsCovsBPWsBcysRIF6bAZMrITEgors0ATFQkrsBIQsRABK7AbMrQDBQA8BCuxHSEyMrQOBQAmBCuyDhAKK7NADgEJK7ADELEnASuxCAXpsSsBK7EnAxESsQULOTkAsR8kERKyCAMNOTk5MDEBFSEVNjMyFhUUBiMiJxUjESMRIxEjNTM1MxUzNTMVFyIGFBYzMjY1NCYCXf7rOWloeHxoaztLWFRERFRYU5JCUFBCRFVTAqAyqVaUf4KdWkMCbv2SAm4yOTk5OdNvuG9vWV5wAAACAEwAAAKGAtkAAwANAFAAsgwAACuwCDOyDQMAK7AGM7QBBAATBCsBsA4vsAzWsQsF6bALELECASuwBTKxCAXpsQ8BK7ECCxESsgEECTk5OQCxAQwRErICBQo5OTkwMQEjATUDExEzESMBESMRARdgAXf391hp/odYAqT9uZgB5P6DAX39JwJP/bEC2QAAAP//AEAAAAODAtkQLwBSAhgAmC4UEGYAMQAAMzNAABAHABACOP8QAAD//wAn//IC+QLEEC8U5wDvAKQuFBAGD3QAAAAAAAIANP9qAh4BxgAtADYAqwCyBQAAK7QLBAATBCuyCwUKK7NACwcJK7AfL7Q0BAATBCuwEy+0KwQAEwQrAbA3L7Ai1rAmMrQyBQARBCuwJzKwMhCxLgErtBwFABEEK7AcELEHASu0CAUAEQQrsAgQsRABK7QABQARBCuxOAErsTIiERKwJDmwLhGyHxkpOTk5sRAIERKyBRMrOTk5ALEFNBESsxwiLjIkFzmxEwsRErUAGSQmKTAkFzkwMSUUDgIjIiczFBYzMj4CNTQmIyIOAwceARUUBiMiJjU0NyY1MxQXNjMyFgE0JwYVFDMyNgIeFSpMMm0CMh4hJzgbDDFCID8sMBgRKCwwLysoKCgyEHOWSlX+ljkVIR0Q/i5aUjOaLjwnQkQlSVgkLU0vJDdcMzBDRy5pV0RqVCr3ev6SPlg4WUchAAMAWwAAAmkC2QAKABIAFgBdALIGAAArtBUEABMEK7IHAwArsRQE6bALMrQEDAYHDSuxBATpAbAXL7AG1rQVBQARBCuwFRCxFgErtAUFABEEK7ALMrAFELEQASuxAAXpsRgBKwCxFAwRErAAOTAxARQGKwERIxEhMhYlETMyNjQmKwIRMwJpcVuKuAEtbHX+qmdDS0tDnkpKAgNdcf7LAtlvHf8ARHhE/a0AAAAEACb/xQLmAuUADgAcACEAKACJALIEAAArsRoE6bIAAAArsgkDACuxFQTpAbApL7AH1rEgBemwIBCxHQErtBgFABEEK7AYELESASuwDzK0IwUAEQQrsCMQsSYBK7EMBemxKgErsRIYERKyCQQQOTk5sSYjERKxAg45ObAMEbEBADk5ALEaBBESsAI5sBURtwcGDgwdHiIkJBc5MDEFBycGIyImEDYzMhYVFAcvATcXESYjIgcRFjMyNyURBhUUAREXNjU0JgLdL2lWaZ7Cwp6dw2eNPy4RMTtANTRAODX+6FcBphFPMgE6VzPTAVbT0qqscRQ1OA4BvRcb/d0aFyoB1VOXlwGJ/jkOWYtOfAAAAAMAAP/vA3kCzQAJAIcAkQFoALIzAAArsCUztEUEABMEK7AaMrJ4AgArsHUg1hG0UAQAEwQrtD45M3gNK7Q+BAA3BCu0bVgzeA0rtG0EABMEK7JYbQorswBYZAkrtAmOM3gNK7QJBAATBCsBsJIvsDbWtEIFABEEK7JCNgorswBCOwkrsEIQsXABK7RVBQARBCuwVRCxKAErtBcFABsEK7IXKAorswAXIgkrs2YXKAgrtF8FABEEK7BfL7RmBQARBCuwFxCxLQErtBIFABsEK7ASELEFASu0CgUAEQQrsZMBK7FVcBESsUUzOTmwXxGwbTmxZigRErFJZDk5sBcRsSpMOTmwLRK3FQkrL1B1iJAkFzmwEhGyAhAUOTk5sAUSsgdOdzk5ObAKEbF4fTk5ALE+RRESsyg2F0IkFzmwORG1HR8iFSpAJBc5sG0SsSsUOTmxjlgRErUQEi9JLZAkFzmwCRGyAkxwOTk5sFAStQUHCk53eiQXOTAxATIXPgE1NCcGByUUDgMHFhUUDwEGFRQWMzI2NzY7ATIVFAYjIiY1ND8BNjUGIwcOASMiJjU0NjMyFRQGIyInBhUUFjMyNj8BNDYzNjcmIyIGBwYVFxYzMjY3PgI9ATQ+ATMyFRQOAQcOASMiJjU0Nz4BMzIXNzIVFA8BFx4IBSIGIyImIyIHNgJmGRREbhhucAEqIjA+KxQMIksbEBkdXS8DBAsJpiIgTw9RNCIiSj7MVTtQLyMhIxQQCQU+MzuOPVsHBY+OPHtq50A3AQdCGEYlBz8mCAwBCh8aHR5tMSY6OD37doVKMgsEJAQEBAgECAQGAwL+7AEEAQQOAwoCGAFtChp5QCcbVbbAJUUvKBQHDxorMGkoGxMIR0QDCBiFMiMWFHFIGwduWIAnJB08Ig4YCA0JGx13VYAEC75mLHdaTzQMNjE1Cks6EwYEBQQSGEQoKSpIKS8/TlaILx4RAwMXBAQECQYLCg0MEN8BAgYCAAACABP/+AKtAuUAIQBIARcAsjEAACuwFDOxOATpsA4ysjgxCiuzQDgQCSuzQDg0CSuyKQMAK7AAM7FCBOmwITIBsEkvsCbWsSQlMjKxRQXpsEYysEUQsT8BK7EsBemwLBCxGgErsQcF6bIaBwors0AaIQkrsAcQsR4BK7QDBQAkBCuxSgErsDYausA5+qoAFSsKBLAlLg6wIsAEsUYF+Q6wSMAEsCUQsyQlIhMrusCt9rYAFSsLsEYQs0dGSBMrskdGSCCKIIojBg4REjkAtSJIJCVGRy4uLi4uLgGyIkhHLi4usEAaAbFFJhESsDQ5sD8RsjE1KTk5ObAsErAuObEHGhESsBg5sB4RsAo5sAMSsg4QFDk5OQCxQjgRErMDGiYsJBc5MDEBMhYVFA4BBxQeBDMyNzMOASMiLgM1PgI1NCYjBS4CNTQ2MzIWFRQOAiMiJjUzHgEzMj4ENTQmIyIGFRQWFwFbjospLCMCBAoQGBAOC1APNDIoOSMUByEmJU9b/sABBQJhTUxXECpMOS1ZVQIYDxkkGA4HAiYmHy8KAQLlTkYpTSsbLkVQNzAXCzE2J0V2hWAYHzQYJyCaEhAaKT9QdVmHvJNHRCwIDRw/RnJiSy5KIRsVPg0AAAMAXQAAAqcC2QAIACYAKgCaALIfAAArsBUztCoEABMEK7IgAwArsSkE6bADMrQdBR8gDSuxHQTpAbArL7Af1rQqBQARBCuwKhCxJwErtB4FABEEK7AEMrAeELEYASuxEQXpsAAg1hGxJAXpsiQACiuzQCQUCSuxLAErsRgeERKwCTmxEQARErAWOQCxKh8RErAUObAdEbIRGA45OTmwBRKwCTmwKRGwJDkwMQE0JisBFTMyNgceAxUUBhUUFhcVIyY9ATQmKwERIxEhMhYVFAYBESMRAipMQ4iISkUSICsTBgESGnEUOj6XtgFQa3M2/odIAglINvs8YA4mMCodCSIIKTgSFy5JQUM//sYC2WVePlL+rgJT/a0AAAAAAgBd/8kDMALZACUALgB7ALIOAAArsg8DACuxKgTpsCEvsAAztCAEABMEK7QMKw4PDSuxDATpAbAvL7AO1rENBemwKjKwDRCxJgErsRMF6bEwASuxJg0RErMABAEWJBc5sBMRsgIZJTk5OQCxDA4RErMCGRwlJBc5sCsRshYaGzk5ObAqErATOTAxBSM3LgcrAREjESEyFhUUBgceARc3MwcXHgEXFSMuAScDNCYrARUzMjYCEV+NAhUIFg0XFBoO8F0BUGtzNj0hJRhcXpEiDUgacQ86EDxMQ+HhSkU3zwQqDyURGgsK/sYC2WVePlIeDjg6h9VHG1EHFw9KIwHESDb7PAAEAF3/mAKnA34AJAAoADAAMwCcALIhAAArsBUzsiIDACuwAzOxJwTpsDAytDMoISINK7ApM7EzBOmwHDIBsDQvsCHWsTEF6bAnMrAxELEYASuxEQXpsC0g1hGxBgXpsgYtCiuzQAYUCSuxNQErsTEhERKwHjmwGBFACwACCQMdIyQmKTAyJBc5sREtERKwFjkAsTMhERKxDjE5ObAoEbAJObAnErAGObAiEbAEOTAxEzcXBx4BFRQGBx4DFRQGFRQWFxUjJj0BNCYrAQMnNyMRITcDNyMVOwEyNjU0JicDNyPaFfQbX2Q2PSArEwYBEhpxFDo+eZg4HiIBLA6IXLGVTEpFRDzwODgDRThZTAZkWD5SHg4mMCodCSIIKTgSFy5JQUM//l4VUwLZJ/6M+/s8QUQ3A/4amf//ACEAtQPmAucQJxTqAAAAzBAHFOQBtgDMAAD//wAbAAAE2ALZECcU4wNcAAAQJxTcAawAABBGADcDADMzQAD//wAUAMsD0gLZECcU5AGiAMwQBxTrAAAAywAAAAEAHv+YAoUDfgAQACcAsggAACuyDQMAK7AFMwGwES+xEgErALENCBEStAMECQwPJBc5MDETNxcDFxMzAyMnBycTAzMbAdoV9MI3ymP9ZDJZOHG0ZICVA0U4Wf3qngJp/SeM9BUBNwH1/o8BmAAAAAACABwAAAJHAtkACQANADIAsgUAACuxCwTpsAIysgkDACuxCATpsAoyAbAOL7EPASsAsQsFERKwBjmwCBGwATkwMQEVASEVITUBITUFATMBAkX+qAFa/dUBUf7LAXb+rU8BWgLZVP3NUlICNVJS/csCNQAA//8AKAAAAs0C3RACAzwAAP//AB3/1wLCArQQCwM8AuoCtMAAAAEAEf90AegCwQBqAQoAshMCACuxAATpsDcvtDYEABMEK7AmL7RGBAATBCuwKS+0QQQAEgQrsEEQsD4g1hGwQzO0MAQAEwQrsFEvtGIEABMEKwGway+wDda0BQUAEQQrsDMysAUQtDoFABEEK7A6L7BUM7RTBQAbBCuwBRCxLQErsFkysUQF6bBEELFLASuxIAXpsCAQsBgg1hG0ZQUAGwQrsGUvtBgFABsEK7FsASuxBToRErAJObBTEbEHXjk5sC0StSswNjc+YCQXObBEEbUTKABBUWIkFzmwSxKxJhs5OQCxKUYRErArObAwEbMtMzpLJBc5sVE+ERKyIFNUOTk5sGIRsRtZOTmwABK0CQ0YXmAkFzkwMRMiDgIVFBcGIyIuATU0PgMzMh4CFRQGBx4DFRQOAyMiJiciBzY1NCYjIgYVFBYzFSImNTQ+ATMyFjMyNxUUMzI+AjU0LgMjIhUjND4CNy4DJzY3FjMyNjU0LgP6EzlEMAsXBgMKCgogMVo5G0ZRN1NbETA2JR0qMyYNITgRDREOGBQZLh0fJysrJw8LNggWISEJGR4VCh0rSi5TPSIxKQ4YIQ0KAQEQO1FKZwkaJUACahAhRS0VIQoUKBcRMkQ4KBUuXD1CbBwEIDRRLSpBJRgIIQEHHhwYHiogEy4hPCYlLwwLC1M3ChUvIBI0RDcnbh82IBMDBxAJCgECEDJbRw0lLSUa//8ADP//AOICExAPA0wBHgILwAD//wBQAAACkwLZEAIALgAA//8ADwAAAosDxhACAIcAAAADAAT/8gOCAsQAbQB4AIMBgACyawAAK7BJM7QOBAATBCuwXTKyOQIAK7I0AgArtBcEABMEK7QIA2s0DSu0CAQAQwQrtFRPazQNK7RUBAATBCu0LB5rNA0rtCwEABMEK7RlgGs0DSu0ZQQAEwQrtHd5azQNK7R3BAATBCsBsIQvsADWtAsFABEEK7ILAAorswALBQkrsAsQsS8BK7QcBQARBCuwHBCxIgErtCkFABEEK7NaKSIIK7RMBQARBCuwTC+0WgUAEQQrslpMCiuzAFpRCSuwKRCxYQErtEYFABEEK7BGELFxASu0QQUAEQQrsYUBK7EcLxESsQ5rOTmwTBGyER4sOTk5sSlaERKxEiU5ObBhEUAKFzRESV1nbnV+giQXObBGErAVObBxEbI2P3M5OTmwQRKyOz45OTk5ALEIDhESswALTFokFzmwAxGwCTmxT1QRErARObAsEbBGObAeErBhObGAZRESsBI5sHkRsURjOTmwdxKyHC9uOTk5sBcRQAkVIiUpNj5BcXMkFzkwMTc0NjMyFRQGIicGFRQWMzI2Nz4CNyYjIgYHBhUUMzI+AT0BNDcyFRYVFAYjIiY1NDc+ATMyFzc2MzIXFA4BBxYVFAYHFhUUBiMiJjU0NjMyFRQGIyIOAxUUFjMyPgE1NCcGIyInBw4BIyImAT4BNTQnBgc2MzIHIg4CBxYzMjcmBC8iISQoCQhCNjuPPUlSmUw/eW/jOTZLOnVBDgkCrWA1LDc89naGSTQBAwcECRYKNVQ3OMBaIC9yWAgHBSdBJRoJIRwsb0wlRDUdEUY/zVU7TgLPKFMbTYAVEycrCw4FDQQCCSQvFz4fPCIOGQ8SCx0deVZnbaQ4J3hRTDVBbnkdCAUGCBIJbZ01IzxOVIEqIQEQAwcQCSw5N2cmIT9arh4kOWoIBQkYISkeChcYWHouLBQlBmJZgicBVR9vMigbT64DFgUFEgUBHQUAAAAAAgAR//MCWALBAGYAegFLALJZAAArsGQztEQEADYEK7JZAAArtBIEABMEK7JEWQors0BESAkrswlEWQgrsQME6bIhAgArtGcEABMEK7IpAQArtCcEABMEK7IpJwors0ApMgkrAbB7L7AA1rQPBQARBCuwDxCxHgErtGoFACYEK7ALINYRtAYFABsEK7BqELF2ASu0OgUAGwQrs3M6dggrtD0FACYEK7A9ELR5BQARBCuweS+wMzOwOhCxNgErtC4FABEEK7F8ASuxHgsRErANObAGEbMDCRJkJBc5sXZqERKyFF0bOTk5sDoRsyFCZ20kFzmxNnkRErEyNzk5sD0RsTEjOTmwLhKwLDkAsRJZERKwUzmwCRGzG1BSXSQXObBEErEADzk5sAMRtwYLDUJGSk9tJBc5sCkStx4qNDo9anN2JBc5sCcRsDU5sGcStiUjKy42N3kkFzkwMTc0NjMyFhUUBiImNTQ3BhUUFjMyPgY3LgE1NDYzMhc2NxYXNxcHJwcWFRQOASImNDY0Jw4BFRQWFRQOAgcWMzI3NjMyFRQOAg8BDgUiBiMiLgEjBw4EIyImASIGFRQWFz4ENTQmNTQ2NyYRKRsWIRQcGgYhLzIIDwoPBxEFFgNMVHNeViohZQ4OEQZzIRwJCwsGDA4FFSZMGhwnAkQxPkEMBwkGBwkBVgUNBQgDBQUEBCVQPwIFBg4XGSQSODUBHUJRSkgCEQYLBENUISROHiUcGBEUFxEKCwceFTUCAQgCDAMSAjGyYZC3RQkLNjAEFSF2Bh4TEiQTCAgnKg8JLSQrkC0ePyMrAh9BDAwDCgYIAVkGDQcHAwQBGB8GBQsOCwhBAnGFa16oMQMbCxkXDSuhLj9RBzAAAAD//wAe/+kB9wIbEAYASAAAAAIAH//1AbsB6wAUACAAVgCyAwAAK7QTBAAfBCuwHS+0CQQAQwQrAbAhL7AG1rERBemwERCxGgErsQsF6bEiASuxGhERErQACQ8DFSQXObALEbABOQCxHRMRErQBBgsAFSQXOTAxJRcGIyImNTQ2MzIVFAYPAQYVFDMyJz4DNTQmIyIGBwFELl9wO0nGcWWscxwKMFpsQ1YjChMQJVMbjCtsTD2T2nY9ahAEKBZIwRAkJhoSERZSOQACABn/+AKzAsQAWgBjAUkAslgAACu0PgQAEwQrsgsCACu0JQQAEwQrtEVQWAsNK7RFBAATBCuyRVAKK7NARUsJK7RhNFgLDSu0YQQAEwQrtC5dWAsNK7QuBAATBCu0IBBYCw0rtCAEABMEK7EWCxAgwC+0GwQAEwQrAbBkL7AA1rQ7BQARBCuwOxCxTQErtEgFABEEK7BIELEHASu0KgUAEQQrsCoQsVsBK7QxBQARBCuwMRCxQwErtFMFABEEK7AeMrBTELQTBQARBCuwEy+yUxMKK7NAUxgJK7BTELEjASu0DQUAEQQrsWUBK7FITRESsT5YOTmxKgcRErEFNjk5sFsRtC40RVBfJBc5sVMTERKwCjmwIxGzCxAWJSQXOQCxRT4RErI7AFM5OTmxXWERErExNjk5sC4RsAU5sBASsCo5sCARsAc5sBsSsRMjOTmwFhGwDTkwMTc0PgI3JjU0PgEyFhUUBiMiJjU0NjMyFRQGIyIGFRQzMjY1NCMiDgIVFBc2MzIWFRQGIyInDgMVFBYzMj4CNTQjIgYHFAcjIjU+ATMyFhUUBw4BIyImATQjIgcWMzI2GTlXRxwQYYp6UmUzHSZZKgkIBSFELSNTfCtYPCUFHhUbMyQUPyUzUi4YTj0xWTYgYSdOCAwEBwhfMTxTGCSURlRuAYY2EA8UKAgRhTpjPiMIFCM+ekoyMTZvHRorWAgDC1AeIF0rSj5UUBQOCgURDhASHBRKTkQWMy8uQDoQOV42BQUJPW4rLyAiMk9GATwKAxEHAAADAAv/6gPAAtgAUwB9AIQBVgCyUQAAK7QOBAATBCuwCC+0AwQAQwQrsEYvtEgEABMEK7BOL7ATM7QzBAATBCuwHjKwey+0bAQAEwQrsIMvtDgEABMEK7BiL7RbBAAfBCuwZS+0WAQAHwQrAbCFL7AA1rQMBQARBCuyDAAKK7MADAUJK7AMELFUASu0agUAEQQrsGoQsW8BK7R4BQARBCuwMzKyb3gKK7NAb3IJK7B4ELFKASu0QQUAGwQrsEEQsYEBK7Q6BQARBCuxhgErsVQMERKxDlE5ObFvahESsxseE3skFzmweBGxIE45ObBKErEyZTk5sEERsjVMWDk5ObCBErUqLDg8KH4kFzkAsQgOERKxAAw5ObADEbAKObBGErIWGBs5OTmwThGxPko5ObAzErIdPEw5OTmwexGyMjV+OTk5sYNsERKyIDqBOTk5sWI4ERK1LFRqb3J4JBc5sFsRsSh1OTkwMTc0NjMyFRQGIyInBhUUMzI+AjcOAQcGKwEiNTQ2Nz4GNzYzMhcUDgEHDgMHNjc+ATMyFRQHBhUUFxUUDwEGIyInIjU0NwYHDgEjIiYTND4BMzIWMzIVFA8BBiMiJiMiDgIVFDMyNjU0JjU0NjMeARUUBiMiJgU+ATUmIyILMCMhJBQTCwiUK2JWOhhAehYCBQsIplIKKhMmHSwzHgEDCAIVPyYNFwwTBSQnI0MWIXQMAQU3AQIDAQUbKB0v+2dGYNl+vFRCxD8JAhwCBEPDQEeFVzVBXHsIDAMRGp1wIzQB6R8tAwgPOx5AIg4ZDxAPQDtfSyYGJSEDCBw9BRBKHzshLiYTARAHEEE1EywfMg0BCDUzHDchExIHAwIFAxYBAQcOLgcBbrYoAZg+j2FNCAMCJwRNNE1VITV7PhATAQUIBCIZR3ojRQshEQcA//8AKQAAAhIC2RAPACkCYgLZwAAAAQAJ/9wEqwLPAG4ArgCyXwAAK7QCBAATBCuyFgAAK7RMBAATBCuyMwAAK7Q/BAATBCuyMz8KK7NAMzgJK7RnbEw4DSuxZwTpAbBvL7Bi1rQABQARBCuwABCxTgErtBQFABEEK7AUELFCASu0MQUAEQQrsXABK7EAYhESsGU5sE4Rs1tfZ2kkFzmwFBKxB0w5ObBCEbEWUzk5sDESsxhESlUkFzkAsQIWERKxFDE5ObFnbBESsWJCOTkwMTcUOwE+Azc2ADc2MxYVFAcGABUUMzIBPgY3PgE/ATYzFxYVFA8BDgEHBhUUMzI2NzY7ATIVFA4BIyImNTQ3PgI3BgcAIyI9AT4ENw4CBw4EIyImNTQ2MzYzMhUUBiMiJy46CSpZOnMgSQFWPAIDEQJr/owDDwEPDR0iGSoVMQgGEgWpAgQLBQF2LZMvRxEtbyABBgsIR2wnHSstHz9JFnZG/vQeLQMQNDeFQkBDYSIWWjxSUiglMxQHEB8jJxMIBi4gAj1BjiVSAQE4AwQJAQSA/fcvBQFAEB8iGSYTKwgFFQWXAgMDBQQBk0D/QWY3FGMrBAgKTEolLEA/K2J2IWtV/sQ5DiYyT0WsWjAzVicZbUNOJh4bECYVJA8aAwAAAP//ADoAAAJGAlgQBgTvAAD//wA6AAACNgJYEAYE8AAA//8AHgAAAbECWBAGBPEAAP//ACYAAAIfAlgQBgTyAAAAAgBDAAAAzwLZAAMABwA5ALICAAArsgcDACu0BgQAEAQrsgMBACsBsAgvsALWsAYytAEFAA8EK7AEMrQBBQAPBCuxCQErADAxExEjETcVIzXPjIyMAhz95AIcvX19AAD//wAk/+wDRAKsEIcANAMJ/8QAAEAAwAAAAAAA//8AKAAABSoC2RAnFO8DTQAAECcU2AF2AAAQRgAp6AAzM0AAAAMAHgAAAkYCDAADAA8AEwB8ALIKAAArsAUztBIEAB8EK7ACMrINAQArtAwEADcEK7MABAcQJBcyAbAUL7AK1rQSBQARBCuyChIKK7NACgwJK7ASELETASu0CQUAEQQrsAkQsQYBK7QCBQARBCuwAhCxAwErtAUFABEEK7IFAwors0AFDwkrsRUBKwAwMQEjETMTESMRIxEjESM1IRUhIxEzAeJISDe2Y7YsAij+g0hIAcb+cAGQ/joBxv46AcZGRv5wAAACAFIAAAI2AtkAAwAJAEcAsgkAACu0AgQAHwQrsgQDACuxAQTpsAYyAbAKL7AJ1rQCBQARBCuwAhCxAwErtAgFABEEK7IIAwors0AIBgkrsQsBKwAwMRMjETMDIRUhESPRSEh/AeT+0rYChf2xAqNU/XsAAAMAUAAAAoAC2QAHAAsADwBgALIGAAArsAEztAkEAB8EK7ANMrIHAwArsQgE6bEDDDIyAbAQL7AG1rQJBQARBCuwCRCxCgErtAUFABEEK7AFELECASu0DQUAEQQrsA0QsQ4BK7QBBQARBCuxEQErADAxAREjESMRIxEXETMRIREzEQKAtsS2N0gBMkgC2f0nAof9eQLZUv2vAlH9rwJRAP//ADz/6QLVAuUQDwAqAv0CzsAA//8AUAAAAhUC2RAPAC8CZQLZwAAAAQBQAAACFQLZAAUALACyAwAAK7EEBOmyAAMAKwGwBi+wBdaxAgXpsgUCCiuzQAUDCSuxBwErADAxATMRITUhAbhd/jsBaALZ/SdS//8ACwAAApMC2RAPADwCogLZwAAAAwA9AAAC2ALZAAoAEwAXAIwAsgAAACuwATOxDATpsRYXMjKyAgMAK7EVBOmxCxQyMgGwGC+wENaxBgXpsRkBK7A2Gro+l/KlABUrCrABLrAVLrABELEWH/mwFRCxAh/5uj6V8pkAFSsKsBcusAsusBcQsQwI+bALELEUCPkDtwECCwwUFRYXLi4uLi4uLi6wQBoAsRUMERKwBjkwMSkBEyEyFhUUDgILATMyNjU0JisCAzMBf/6+mwEtZm0/ZHo8eWdlpElHnkp5SgLZfnRmuX5KAof9y+GmVFr9yQAAAAACABsAAQHrAscAFAAdAH8AsAMvtAAEACsEK7AUL7QWBAArBCuwBS+wFTO0CAQAKwQrsAwysgUICiuzQAUHCSuyCAUKK7NACAoJKwGwHi+wB9a0BgUAGwQrsAYQsQMBK7AJMrQABQAbBCuxCxUyMrAAELEaASu0EAUAJgQrsAEysR8BKwCxBRYRErAQOTAxJTMVIREjESMRMzUzFTMyFhUUBisBNRUzMjY1NCYjARPY/t5lSa5KR0RMSzhUPyIqKSNEQwIf/lEB8mRkUEI+W+ikNCMiKwAAAP//AB7/9AJnAtAQDwAJApsCucAAAAQAJP/sBJEC2QADAAsADgBFASYAsisAACuwAjO0NgQAHwQrsgADACuwCTOyDwEAK7QbBAAfBCu0DgUCDw0rsAQztA4EAB8EK7AMMrIFDgors0AFCwkrsQYKMjIBsEYvsC7WtDMFABsEK7NAMy4IK7QeBQAbBCuwMxCxGQErtBQFABsEK7AUELAlINYRtDkFABsEK7A5L7QlBQAbBCuxRwErsDYausB7+CsAFSsKsAsusAkusAsQsQob+Q6wCRCxDRv5uu53wnMAFSsKDrA9ELA8wLEhC/mwIsAFsA0QswQNCxMrswwNCxMrAwC0DSEiPD0uLi4uLgFACgQJCgsMDSEiPD0uLi4uLi4uLi4usEAasTkeERK0AA8bATYkFzkAsQU2ERKzJS4wQCQXObAOEbMUFhkeJBc5MDEBMwEjEyMHIwEzEyMvAQclMh4CFRQHIzY1NCMiBhUUFh8BHgEVFA4DIyImNTQ3MwYVFBYzMjY1NCYvAS4BNTQ+AwO1Ov2OOk7NWEgBK1ZJSRsdiQMJL0MiDwY/A248UR8qfC0rCyAzXDpSXAc+Azo9S1knK3skLAgcLVYC2f0TAX6eAg3989bw8HQYJygUDRsTB044LhgaDCMNPCAPJzgtIUpBFRgSCzIuPy0aIgwjCjUiDSM3LCEAAAD//wAjAAABhAINEA8AKQG9Ag3R6///ADH/7AM8AtkQIwB1Afr+fBAjDKEBMQAAEAIAe+yq//8AGf/sA1sC2hAjAHUCGf56ECIAdAarEAMMoQFtAAD//wBF/+wDXwLaECMMxQIZ/oAQAg1sAAD//wAe/+wDXwLfECMMxQIZ/oEQIgB0C7AQAwyhAW0AAP//ACT/7ANVAtoQIwzFAg/+fxAiAHUUqRADDKEBYwAA//8AHv/sA18C2RAjDMUCGf5/ECIMxAqpEAMMoQFtAAD//wBF/+wDVgLaECMMxgIP/nwQAg1sAAD//wAc/+wDYALZECMMxgIZ/n0QIgzFCqcQAwyhAW0AAP//AEX/7ANXAtoQIwzIAg/+eRACDWwAAP//ABr/7ANhAtoQIwzIAhn+exAiAHUKqRADDKEBbQAA//8AJv/sA1cC2RAjDMgCD/59ECIMxRSnEAMMoQFtAAD//wA0/+wDTQLZECIMxx6nECMMyAIF/nkQAwyhAUUAAP//AEX/7AKfAtoQIgB7AKsQAwyhAUUAAP//AGQAAADCAtkQAgAsAAD//wBkAAAB2ALZECMALAEWAAAQAgAsAAD//wBkAAAC7gLZECMALAIsAAAQIwAsARYAABACACwAAP//AGQAAAOMAtkQIwA5ARYAABACACwAAP//AA8AAAJ2AtkQAgA5AAD//wAPAAADXQLZECMALAKbAAAQAgA5AAD//wAPAAAEcwLZECMALAOxAAAQIwAsApsAABACADkAAP//AA8AAAWJAtkQIwAsBMcAABAjACwDsQAAECMALAKbAAAQAgA5AAD//wBkAAADmALZECMAOwEWAAAQAgAsAAD//wAPAAACggLZEAIAOwAA//8ADwAAA10C2RAjACwCmwAAEAIAOwAA//8ADwAABHMC2RAjACwDsQAAECMALAKbAAAQAgA7AAD//wBQAAACFQLZEAIALwAA//8AKP/pAp0C5RACACYAAP//AFAAAAKSAtkQAgAnAAD//wBQAAAC/gLZEAIAMAAA//8AQgAAAJYC2RACAEwAAP//AEIAAAF0AtkQIwBMAN4AABACAEwAAP//AEIAAAJSAtkQIwBMAbwAABAjAEwA3gAAEAIATAAA//8AQgAAAsQC2RAjAFkA3gAAEAIATAAA//8ACgAAAeYCDBACAFkAAP//AAoAAAKKAtkQIwBMAfQAABACAFkAAP//AAoAAANoAtkQIwBMAtIAABAjAEwB9AAAEAIAWQAA//8ACgAABEYC2RAjAEwDsAAAECMATALSAAAQIwBMAfQAABACAFkAAP//AEIAAAKwAtkQIwBbAN4AABACAEwAAP//AAoAAAHSAgwQAgBbAAD//wAKAAACigLZECMATAH0AAAQAgBbAAD//wAKAAADaALZECMATALSAAAQIwBMAfQAABACAFsAAP//ADwAAACQAtkQAgBPAAD//wAe/+kB3AIbEAIARgAA//8AHv/pAfMC2RACAEcAAP//ADwAAALwAhsQAgBQAAAAAQAg//EDrgH/AAwAIwCyBQAAK7ACL7QMBAAfBCsBsA0vsQ4BKwCxDAIRErAHOTAxARUhFhcHJic2NxcGBwOu/OUyeSNkl5dkI3kyARQ4MZcjd5CQdyOXMQAAAAABAC0AAAI7A44ADAAjALIBAAArAbANL7AB1rQABQARBCuxDgErsQABERKwBzkAMDEhIxEGByc2NxYXByYnAVA4MZcjd5CQdyOXMQMbMnkjZJeXZCN5MgAAAQAx//EDvwH/AAwAIwCyCQAAK7AAL7QBBAAfBCsBsA0vsQ4BKwCxAQARErAHOTAxNzUhJic3FhcGByc2NzEDGzJ5I2SXl2QjeTLcODGXI3eQkHcjlzEAAAEALf/qAjsDeAAMACMAsgcAACsBsA0vsAzWtAIFABEEK7EOASuxAgwRErAHOQAwMQEzETY3FwYHJic3FhcBGDgxlyN3kJB3I5cxA3j85TJ5I2SXl2QjeTIAAAAAAQAY//EEAAH/ACEAKACyFgAAK7ANM7ASL7QABAATBCsBsCIvsSMBKwCxABIRErEJGjk5MDETIS4BJzceAhcOAgcnPgE3IR4BFwcuAic+AjcXDgGLAwJBODIlNi9eNjZeLzYlMjhB/P5BODIlNi9eNjZeLzYlMjgBEkRDRiBANmEwMGE2QCBGQ0REQ0YgQDZhMDBhNkAgRkMAAAAAAQEF/+oDEwOOACEAJQCyGgAAKwGwIi+wANa0EgUAEQQrsSMBK7ESABESsQkaOTkAMDElEQ4BByc+AjceAhcHLgEnET4BNxcOAgcuAic3HgEB8kRDRiBANmEwMGE2QCBGQ0REQ0YgQDZhMDBhNkAgRkNdAr5BODIlNi9eNjZeLzYlMjhB/UJBODIlNi9eNjZeLzYlMjgAAAABABQAGAMOAxMAFAA2ALAUL7ASM7QNBAAfBCsBsBUvsAnWtAQFABsEK7ACMrEWASuxBAkRErAGOQCxDRQRErAQOTAxJQcBMBUUByM2NTQnFjMyNxUGIzAjAw4o/XQVMQoCWCJxga9TBUAoAo4FU6+BcSJYAgoxFf//ABMAGAMPAxMQhw2T//wDJgAAwABAAAAAAAD//wAUABgDDgMTEA8NkwMiAyvAAP//ABMAGAMPAxMQhw2TAyYABAAAQADAAAAAAAAAAQAc/+4DqwICABEAQACyAgAAK7EABzMzsAQvtA4EAB8EK7IOBAors0AOEAkrAbASL7AC1rAPMrQABQARBCuxEwErALEOBBESsAk5MDEFMCM1IRYXByYnNjcXBgchNTMDqzj9HDJ5I2SXl2QjeTIC5DgS7jGXI3eQkHcjlzHuAAABAEn/MAJeAsAAEQBXALIJAgArsAAvtAIEAB8EK7APMgGwEi+wA9a0DwUAEQQrsg8DCiuzQA8RCSuyAw8KK7NAAwAJK7ACMrETASuxDwMRErAJOQCxCQIRErQEBwsMDiQXOTAxFzA1MxEGByc2NxYXByYnETMVSu4xlyR3kZB2Ipgw7tA4AuQxeSJll5dlInkx/Rw4AAAA//8AMP/uA78CAhAPDZcD2wHwwAD//wBJ/zACXgLAEA8NmAKnAfDAAAABABz/8QOuAf8AFwBOALIKAAArsAcvtBEEAB8EK7AXL7QABAATBCsBsBgvsBTWtAMFABEEK7IUAwors0AUAAkrsRkBKwCxEQcRErAMObAXEbADObAAErAPOTAxATIWFRQGIyEWFwcmJzY3FwYHITI1NCYjAwxOVFZJ/YAyeSNkl5dkI3kyAn1pMzYB5kc7REQxlyN3kJB3I5cxUSMrAAAAAQAt//EDvwH/ABcATgCyDgAAK7ASL7QGBAAfBCuwAS+0AAQAEwQrAbAYL7AV1rQEBQARBCuyBBUKK7NABAAJK7EZASsAsQYSERKwDDmwARGwFTmwABKwCTkwMRMVIgYVFDMhJic3FhcGByc2NyEiJjU0Ns82M2kCfTJ5I2SXl2QjeTL9gElWVAHmMysjUTGXI3eQkHcjlzFERDtHAAAAAAEAFAANApkCWAAIADMAsAAvtAEEAB8EKwGwCS+wB9a0AwUAEQQrsgcDCiuzQAcACSuxCgErsQMHERKwBTkAMDETNSERMwcnMxEUAjFUcG9UAiE3/lumpgFuAAAAAQAP//ACWgJ1AAgAOACyBAAAK7ADL7QHBAAfBCuyBwMKK7NABwAJKwGwCS+wCNa0AgUAEQQrsQoBKwCxBwMRErAFOTAxATMRIRUnNxUhAiM3/lumpgFuAnX9z1Rwb1QAAQAgANwDrgH/AAcAFgCwAi+0BwQAHwQrAbAIL7EJASsAMDEBFSE2NxcGBwOu/HKJkiN5MgEUOHatI5cxAAAAAAEAIP/sA64BDwAHABsAsgQAACuwAS+0BgQAHwQrAbAIL7EJASsAMDElIRYXByYnIQOu/QUyeSOSiQOO1zGXI612AAD//wA4/2IBXALxEIcNn/9cAxAAAMAAQAAAAAAA//8AI/9fAUcC7hCHDaAAOAMOAADAAEAAAAAAAP//ACAA3wOuAgIQDw2gA84B7sAA//8ALf/0A7sBFxAPDZ8D2wHzwAD//wA4/5EBXAMgEIcNoAFI/3IAAEAAwAAAAAAA//8AIP+SAUQDIRCHDZ8CIP9yAABAAMAAAAAAAP//ACD/RwO/AqkQJw2PAAAAqhAHDY0AAP9WAAD//wAU/yUDdgLEEIcNpwDNAuQAAMAAQAAAAAAA//8AIP9HA78CqhAnDY8AAP9WEAcNjQAAAKsAAAABACD/SwOuAyAAGwA0ALANL7QKBAAfBCuwAi+0GwQAHwQrAbAcL7EdASsAsQoNERKwEjmwAhGwFDmwGxKwFjkwMQEVIRYXDgQHIRUhFhcHJic2NyYnNjcXBgcDrvzlK4AJLx8pIAsDG/zlMnkjZJeHVlaHl2QjeTICNTgqnQs6JDEjCzgxlyN3kIFjYoGQdyOXMQAAAQAO/24D5AL8ABcAOAABsBgvsAjWtAcFABEEK7AHELEBASu0AAUAEQQrsRkBK7EHCBESsA45sAERsBA5sAASsBI5ADAxBSMRBgcmJxEjEQYHJzY3Fhc2NxYXByYnAvg4MpWhJjg1kySBh3ZtbXaHgSSTNZIDHDN4hCf85AMcNnYkbY18YGB8jW0kdjYAAAD//wAq/0sDuAMgEA8NqgPYAmvAAP//AA7/bgPkAvwQDw2rA/ICasAA//8AIP+QA7sCZRAmDZ8AZhAGDaQAnAAA//8AIP+VA64CWBAmDaMAVhAGDaAAqQAAAAEAHv/xA6sCAQARAC0AsgkAACuwBy+0BAQAEwQrsAIvtBEEABMEKwGwEi+xEwErALECBBESsAw5MDEBFSEHFyEVIRcHLgEnPgE3FwcDq/0YUVEC6P1ITSlCXFtbXEIpTQF+NVBQNWIhUWFWVmFRIWIAAAAAAQAnAAICNwOPABEALAABsBIvsBDWtA8FABEEK7APELELASu0CgUAEQQrsRMBK7ELDxESsAQ5ADAxEyc+ATceARcHJxEjEScHESMRSCFRYVZWYVEhYjVQUDUCbSlCXFtbXEIpTf1IAuhRUf0YArgAAAEALf/sA7oB/AARAC0AsgAAACuwAy+0BAQAEwQrsAgvtAkEABMEKwGwEi+xEwErALEIBBESsA85MDEFJzchNSE3JyE1ISc3HgEXDgECwSlN/UgC6FFR/RgCuE0pQlxbW1wUIWI1UFA1YiFRYVZWYQABACz/7QI8A3oAEQAxALIEAAArAbASL7AJ1rQMBQARBCuwDBCxDgErtBEFABEEK7ETASuxDgwRErAEOQAwMQEXDgEHLgEnNxcRMxEXNxEzEQIbIVFhVlZhUSFiNVBQNQEPKUJcW1tcQilNArj9GFFRAuj9SAAAAAACABv/7AP/Af4AFQAbADIAsg4AACuwCTOwDC+0FgQAEwQrsBovtAAEABMEKwGwHC+xHQErALEaFhESsREGOTkwMRMhJzceARcOAQcnNyEXBy4BJz4BNxcDITcnIQfxAjhMKFBYUlJYUChM/chMKFBYUlJYUCh4ApFUVP1vVAF9XyJgXktLXmAiX18iYF5LS15gIv7DVlZWAAIAJ/+fAjcDIQAVABsALgABsBwvsBTWtBkFABEEK7AZELEbASu0CgUAEQQrsR0BK7EbGRESsQ8EOTkAMDETJz4BNx4BFwcnETcXDgEHLgEnNxcRNycHERc3SCFRYVZWYVEhYmIhUWFWVmFRIWLVUFBQUAH/KUJcW1tcQilN/ihNKUJcW1tcQilNAdgwUVH9yFFRAP//ACD/+AQvAgYQDw23BE8B/sAAAAEAIP/4BC8CBgA2AGQAsjQAACuwBC+wDDO0JwQAKwQrsAEvsBYztCwEAB8EK7AXMrARL7QbBAArBCuwIzIBsDcvsTgBKwCxBDQRErA1ObEBJxESsgoeHzk5ObAsEbMPFCoyJBc5sBESsgcIITk5OTAxJSMiBiMiLgEnDgIjIi4CIyIOAiM1Mj4BMzIeARc+AjMyHgEzMj4COwEmJzcWFwYHJzYDvGAedx0XOjwRET05ExIyKSwMDygjNxwcQT4YFzk7ExI8ORMWRD0PDSgjNBhnMnkjZJeXZCN542dOYw0MYlA+ST4dIh04NTRPYw0NYlBjYxwjHDGXI3eQkHcjlwACABEAAAKNAtkABwAKACwAsgQAACuyBQMAK7ABM7QHCQQFDSuxBwTpAbALL7EMASsAsQkEERKwCjkwMQE3MwEjATMXBSMTAdpLaP8AeP78Y00A/+h4Af7b/ScC2dtO/rQAAAAAAQBY/3UCTANdABsAWACwAy+xGATpshgDCiuzQBgACSuwES+xCgTpshEKCiuzQBENCSsBsBwvsAbWtBUFADwEK7AVELEbASuwDjK0AAUAPAQrsA0ysR0BK7EbFRESsQoDOTkAMDElFAYjIiY1ETQ2MzIWFSM0JiMiBhURFBYzMjY1AkyKcGiSkmhxiVJXUUpdXklQWG9tjZNnAfRoko5sTVteSv4MSV5bTAAAAAIAK//pAgECxQAZACUAagCyCAAAK7EgBOmyAAIAK7ETBOm0DhoIAA0rsQ4E6bMXCAAIKwGwJi+wC9axHQXpsB0QsSMBK7AQMrEGBemxJwErsR0LERKwFzmwIxG0AA4TFggkFzmwBhKwETkAsRogERKyBgsQOTk5MDEBMh4DFRAjIiY1NDYzMhcuASMiBgcjPgETIgYVFBYzMjY1NCYBAyNARzMh7mWDel9pOgFRTC4+C1gNa11ASlA9PlJSAsUQM1KPXv6mh2hjfk+CizgzV2L+plNHQ1dbREJTAAABAFAAAAJKAtkACwBDALIJAAArsQoE6bIGAwArsQUE6bQCAQkGDSuxAgTpAbAML7AL1rADMrEIBemyCwgKK7NACwkJK7EBBTIysQ0BKwAwMQEhNSE1ITUhESE1IQHt/mMBnf5kAfn+BgGdAUxS6VL9J1IAAAMAUP+cAkoDIAATABcAGwB1ALIJAAArsAQzsQoE6bAUMrIJCgors0AJBgkrshIDACuwAjOxEQTpsBgyshIRCiuzQBIACSu0Dg0GAA0rsBYzsQ4E6bAZMgGwHC+wFdawGjKxBAXpshUECiuzQBUJCSuxDREyMrEdASuxBBURErECATk5ADAxATMHMxEhByM3IzUzNyM1MzchNSEDITUjEwczNQHVNx1b/nwpNyk/YGbG6F/+ugFn0QEGoIFffgMgR/0nZGRS+lLpUv15+gE76ekAAAAAAwAo//IC+gLGABMAGwAjAH8AsgcAACuwCjOxHwTpshECACuwADO0FAQANwQrAbAkL7AO1rALMrQXBQAmBCuwFxCxIgErtAQFACYEK7ABMrElASuxFw4RErAKObAiEbcHCQwREwIaHSQXObAEErAAOQCxHwcRErALObAUEbcCBAwOCRMZHCQXObARErABOTAxARcHFhUUBiMiJwcnNyY1NDYzMhcnIgYVFBcBJhcBFjMyNjU0AsgyU1PUlYJiTzZSUtaZfWHfcbI/AY9PgP5zTl52qALGMlNnf5XUUVAyUmWCldFRC7BwXlEBj0Bz/nA/rHNgAAIACgAAAr0C2QADAAYAIgCyAAAAK7EFBOmyAQMAKwGwBy+xCAErALEBBRESsAQ5MDEzATMJAQMhCgEmZAEp/qbUAacC2f0nAmj96gACAAoAAAK9AtkAAwAGACIAsgMAACuyAAMAK7EGBOkBsAcvsQgBKwCxBgMRErAEOTAxEyEBIzcTIQoCs/7XZDPT/lkC2f0ncQIWAAAAAQA3AAACEgJoABcAVQCyAAAAK7QVBAA3BCuwEC+0DQQANwQrsAsvtAgEADcEKwGwGC+wBda0EAUAGwQrsA0yshAFCiuzQBAPCSuwCTKzQBAXCSuxGQErALENEBESsAU5MDEhIi4CNTQ2OwEVIwYHIRUhHgM7ARUBfkVzXDOzmJCU7xEBlP5tBS1JUDSMIUZ5UpieRgfKRjtRKRBGAAAAAAMAN//CAhICrwAZAB0AIQFFALIPAAArtAwEADcEK7AcL7EJGzMztCEEADcEK7EGHjIysAUvtAIEADcEK7ICBQors0ACAAkrsAEyAbAiL7AW1rQcBQAbBCuwITKyHBYKK7NAHAgJK7ADMrNAHA0JK7EjASuwNhq6PQXssQAVKwqwAC4OsBPABbEBCPkOsBLABbASELMCEgETK7MFEgETK7MGEgETK7MJEgETK7o9BeyxABUrC7MKEgETK7MREgETK7ATELMUEwATK7MZEwATK7MaEwATKwWzGxMAEyuzHhMAEyu6PQXssQAVKwuzHxMAEyuyFBMAIIogiiMGDhESObAaObAfObAZObIREgEREjmwCjkAtwoREhMUGRofLi4uLi4uLi4BQBAAAQIFBgkKERITFBkaGx4fLi4uLi4uLi4uLi4uLi4uLrBAGgEAsQIFERKwGDkwMQEzBzMVIwczFSMHFjsBFSMiJwcjNyY1NDY3AzcjFj8BBgcBdDcWfZRC1uw3NlmMjF5FHTcldZ6InC5wCX1Bug4Cr0dG0UauF0YdW3RNr46dCv4SkmKozBqyAAEALQABAfkB1QAYADIAsBYvtBMEACsEK7AOL7QLBAArBCuwBi+0AwQAKwQrAbAZL7EaASsAsQsOERKwADkwMTc0NjsBFSMiDgIHIRUhHgM7ARUjIiYtgV7t7REhLyUJAXz+hAkmLyAR7e1hfutyeEQIGDkrRCs6FwdFfv//ADf//wISAmcQCw3AAkkCZ8AAAAMAN//EAhICsQAbAB8AJgE8ALINAAArsQkMMzO0DgQANwQrsQ8hMjKyDQ4KK7NADQoJK7ALMrARL7EQIDMztBIEADcEK7ETHTIysBcvtBgEADcEKwGwJy+wJtawHjK0BAUAGwQrsiYECiuzQCYRCSuwFzKzQCYNCSuxKAErsDYauj0F7LEAFSsKsAsuDrAAwAWxCgj5DrABwLMCCgETKwWzCQoBEyuwCxCzDAsAEyuzDwsAEyuzEAsAEyuzEwsAEyu6PQXssQAVKwuzFAsAEyuzGwsAEyuwChCzHAoBEysFsx0KARMrsyAKARMrsyEKARMrshQLACCKIIojBg4REjmwGzmyHAoBERI5sAI5ALUAAQIUGxwuLi4uLi4BQBAAAQIJCgsMDxATFBscHSAhLi4uLi4uLi4uLi4uLi4uLrBAGgEAsRIRERKwBDkwMQEzBxYVFA4CDwEjNyM1MzcjNTM3JicjNTMyHwEHMyYPAT4DNwF0NyWMMlpxRBM3E1txPrfOPDJElJBQPxo0jwmdPi9IQCcFArF0Tr1ReEYiATw8RsVGvhECRhZap3O5xAITK003AP//AFD//wIcAdMQCw3CAkkB1MAA//8AYQBBAY0CmRAHD1f/ZwAAAAAAAQBV/5wCuQMvAAcAPACwBS+0AAQAHgQrsgUACiuzQAUHCSuwAjIBsAgvsAfWtAYFABoEK7AGELEDASu0AgUAGgQrsQkBKwAwMRMhESMRIREjVQJkdv6IdgMv/G0DLvzSAAAA//8AVf+cArkDLxAPDccDDgLLwAAAAQAo/5wCswM4AAsANgCyBQAAK7QIBAA1BCuwAy+0AAQAKgQrAbAML7ENASsAsQUIERKwCTmwAxGwCjmwABKwCzkwMRMhFSEJASEVITUJATcCb/4lAU3+qAHz/XUBZ/6oAzhg/p7+hV9KAZABagAAAAEAMgDFAhYBCwADAB0AsAIvtAMEADcEK7QDBAA3BCsBsAQvsQUBKwAwMQEVITUCFv4cAQtGRgD//wAy//UCFgJvEAsAcwJIAmTAAP//ADIAAQIWAn8QJwB5AJkBNBAGAA4AC/////z/7AIIAtkQAwyhAK4AAAAAAAEAKP/sAWACIAADABsAsgIAACsBsAQvsAPWtAEFAAcEK7EFASsAMDEbASMDc+1L7QIg/cwCNAAAAQA1ADsBvwHaABEAHAABsBIvsAHWsAgytAAFABsEK7AKMrETASsAMDElIzUHJzcnNxc1MxU3FwcXBycBHUZ/I39/I39GfyN/fyN/O5NKPUlJPUmSkkk9SUk9SgACAD8AWwG0Ac8ACwAWAEwAsAMvtBQEACsEK7APL7QJBAA3BCsBsBcvsAbWtBIFABsEK7ASELEMASu0AAUAGwQrsRgBK7EMEhESsQkDOTkAsQ8UERKxBgA5OTAxARQGIyImNTQ2MzIWBzQmIyIGFBYzMjYBtG1NT2xtTk1tRkIyMEVFMDRAARVObGxOTW1tTTJCRGBFQQAA//8AlgC0AZABrhACDH9L2AABAAf/3AIAA5QABwAAARcLAQc1NxMByjaY6HmUtAOUCPxQAeI/QUr+iAAA//8AB//cAgADlBAiDdIAABALAHUARwDPNmYAAP//AAf/3AIAA5QQIg3SAAAQCwzEAEAAzjZmAAAAAgAZAHwCcQGUAAkALwBQALAqL7AmM7QDBAAfBCuwIDKwBy+wHDO0CgQAKwQrsBUyAbAwL7At1rQABQAbBCuxMQErALEDKhESsCQ5sAcRtAwaIigtJBc5sAoSsBc5MDETFBYzMjcmIyIGNzIXPgczMhcOAQcmIyIHFjMyNxYXBiMiJwYjIiY1NDZcKiRAUFU/IydLVGoBGwkdESAZIRErIwcdBxASQFVQQRgRDhofKGNjZGA5TksBBBwsTEgucmEBGAgXChEIBhcJJAgISEwJESIWYWFZNTlRAAAAAAMAGQB8ArEBlAAaACQALgBgALAVL7ARM7QeBAAfBCuwJTKwIi+wKzO0AAQAKwQrsAsyAbAvL7AY1rQbBQAbBCuwGxCxKAErtA4FABsEK7EwASuxKBsRErUACxEVIC0kFzkAsSIeERKzDgIYEyQXOTAxEzIXPgczMhYVFAYjIicGIyImNTQ2BxQWMzI3JiMiBgUyNjU0JiMiBxanVGoBGwkdESAZIRFCTE45Y2NkYDlOSwgqJEBQVT8jJwHEJigoIkBVUAGUYQEYCBcKEQgGWjA1WWFhWTU5UZAcLExILmYrHR4uSEwAAAABAD4AAAJLAg0ABQAyALIBAAArtAQEADcEK7ICAQArAbAGL7AB1rQEBQAbBCuyBAEKK7NABAAJK7EHASsAMDEpAREzESECS/3zRgHHAg3+OQAAAAABABoAAALiAsgABQAYALIFAAArtAIEADcEKwGwBi+xBwErADAxARUBIRUhAuL96wIV/TgCyGT94kYAAAACABr/nALiAjIAFAAZADoAsg4AACuwBzO0FgQANwQrsAUyAbAaL7AN1rAXMrQIBQAbBCuwBTKxGwErsQgNERKyAQoAOTk5ADAxARUHHgEXMxUjBgcnNjchASYnNxYfAQEhNCYCTFA/SAFeYwkVNg4J/dgBfywhGTEsEv75AXo+AjJmUj2gV0Y0MBYeMAF/Gwo1Eh9X/vVNiwAAAAACADL/6AIvAkMABQAeACsAsgsAACuwCDMBsB8vsALWtB0FABsEK7EgASuxHQIRErMGCRgbJBc5ADAxJTY1NCcNARcVJwYHJz4BNyU1JS4BJzcWFzcVBxYVFAGtGxr+4wFcQmIODT0DEwP+pAFeBBADOQ4PYEEkfUlRUEiYvCRPMxgWJgYdBrdFuAcfBiYYGTJPI1lhYgAAAAEARv/yAIICpAADACIAsgAAACsBsAQvsADWtAMFABsEK7QDBQAbBCuxBQErADAxFxEzEUY8DgKy/U4AAAEAHv/yAQICpAALACEAsgoAACsBsAwvsArWsAIytAkFABsEK7AEMrENASsAMDE3NTcRMxU3FQcRIxEeUDxYWDzqTlABHN9YT1j+fAFIAAD//wBG//IA+gKkECYN23gAEAYN2wAAAAAAAQAe//IBNgKkABMATgCyEgAAK7ANMwGwFC+wEtawAjK0EQUAGwQrsAQyshIRCiuzQBIBCSuwERCxDgErsAYytA0FABsEK7AIMrINDgors0ANCwkrsRUBKwAwMTc1NxEzETc1MxU3FQcRIxEHESM1HjI8PDwyMjw8PLlOMgFr/tE887cyTzL+VAFwO/7L+QD//wAeAAACQgHAEA8N4AJgAcDAAAABAB4AAAJCAcAABQARALIFAAArAbAGL7EHASsAMDETMxsBMwEeWri4Wv7uAcD+ygE2/kD//wAo//8C3AH8EA8N4gMEAevAAAABACj/7wLcAewAEAA6ALIFAAArtA0EADcEKwGwES+wB9a0CgUAGwQrsAoQsRABK7QCBQAbBCuxEgErsRAKERKxBAU5OQAwMQEzFRQGICY9ATMVFBYzMjY1ApRIzP7kzEisZmSuAey0g8bGg7S+YpeYYQAAAAEAPP8KAZ8C/wAXADMAsAUvsQoE6bAVL7EQBOkBsBgvsAzWsQAF6bEZASsAsQoFERKwBzmwFRGyAAgNOTk5MDEFFA4CIyInNxYzMjURNDYzMh8BJiIGBwETJTw+IQ0KAhMPXmRIHRcBGUIwAQJFZTMXA1YIhAJTWnMEUgVCTAD//wA8/woCjwL/ECIN4wAAEAMN4wDwAAD//wA8/woDVwL/ECIN4wAAECMN4wDcAAAQAw3jAbgAAAADADf/CgGeAv8ABQANADYAegCwFy+xHATpsDAvsSsE6QGwNy+wJNa0CQUAEQQrsAkQsR4BK7EGJzIysRIF6bEAMzIysBIQsQIBK7QOBQARBCuxOAErsQkkERKyFxkcOTk5sQ4CERKxKzA5OQCxHBcRErAZObAwEbcFBg0RGgAnLiQXObArErAtOTAxJTY1NCYvAQ4BFRQeARc3FAYHFRQOAiMiJzcWMzI9AS4DNTQ2NzU0NjMyFxUmIyIGBxUeAQETUCslVSQtCycf2044JTw+IQ0KAhMPXig6GgtCRWRIHBgfGiEwAT5IpiBXJjwNAQw+LxAmLwp6SlkOcEVlMxcDVgiEjgksNisRPGUQbVpzBVMHQkxcD1sABAAy/wQC0QL/AEoATwBZAF4A4ACwGC+xHQTpsAoysBog1hGwBTOxGwTpsAgysA8vtFgEACsEK7BTL7BRM7Q1BAA3BCuwNzKwLy+wQDOxKgTpsDsysCoQsCwg1hGwPTOxLQTpsD4yAbBfL7Aj1rFdBemwXRCxHwErsSZaMjKxEgXpsTJVMjKwEhCxDAErsTdQMjKxAAXpsUNLMjKwABCxTQErsUcF6bFgASuxXSMRErIYHRo5OTmxDBIRErMFByosJBc5sUdNERKyO0A9OTk5ALFYDxESshEgSjk5ObBTEbVHI09LWlskFzmwNRKxJkQ5OTAxBRQOAiMiJzcWMzI9AQYjIicVFA4DIyInNxYzMj0BLgE1NDY3NTQ2MzIXByYjIgYHFTYzMhc1NDYzMhcVJiMiBgcVHgEVFAYHNTY1NCcHNSYjIgcVFjMyJzUGFRQCISU8PiENCgITD14kJisoGSc1MRoNCgITD15NW1tNZEgcGAEdGyEwASgrJiRkSBwYHhshMAFQYGBQUFBVIycrKCgrJ89IAkVlMxcDVgiEZgQFTjhYNSINA1YIhIAYVjQzVhmPW3IFUwdCTGsGBYJacwVTB0JMgRhYNDVXGEohOTghyd8FB9sHIagiMjEAAAD//wCQAAwCkAHQECcAeQHR/ykQJwB5ADn/KRAHAHkBBQCFAAD//wCQAAwCkAHQEA8N6AMgAdzAAP//AEkAAACxAgwQJwB5//L/HRAHAHn/8gDBAAD//wBJAAACIwIMECcN6gFyAAAQBg3qAAD//wAyAMUCFgHuECYNygAAEAcAeQCdAKP//wAyAAAC4gHuECYNygAAECcAeQIjAKMQBwB5AiL/Hf//AC//6gIgAe4QJg3KAAAQJwB5AWEAoxAnAHkBYP8HECcAef/Y/wcQBwB5/9gAo///ACEAKAHSAg0QJg3wAAAQJwB5AHwAwhAHAHkAe/9F//8AIQDOAdIBeBAGAGEAwgABACMAzgHUAXgAGAB0ALATL7QABAArBCuyABMKK7NAABYJK7AOL7QFBAArBCuyDgUKK7NADgkJKwGwGS+wFta0FwUAEQQrsBcQsQoBK7QJBQARBCuxGgErsRcWERKwFTmwChGxBRM5OQCxABMRErARObAOEbECEDk5sAUSsAM5MDETMj8BNjMyFh0BIzU0JiMiDwEGIyImJzMWjRQXYionMDk1GBsWHHUbGzE3BDUGAREOPxpFOhAFJSERRRBLRk4AAAAAAQBLAHoB8gGKACUAsQCwBi+0IAQAHwQrsBMg1hG0EgQAHwQrsA0vtBkEAB8EK7AAINYRtAEEAB8EKwGwJi+wFta0EAUAEQQrshAWCiuzQBATCSuwEBCxIwErtAMFABEEK7IjAwors0AjAQkrsScBK7A2GrrCXO7HABUrCg6wChCwCcCxHB35sB3AALMJChwdLi4uLgGzCQocHS4uLi6wQBoBsSMQERKyBhkgOTk5ALENEhESswMQFiMkFzkwMQE1FhUUBiMiJi8BLgEjIgYVFBcVIiY1NDYzMhYfAR4BMzI2NTQmAWuGQzksNA4OCRoVGyA+OT9BNy4yEQ4IGhUcIikBUTgDgj9KLDIzIB4nIEECOD86OkYvOzEcGCsjLCH//wAl//cAzwGoEIcN8AGd/9YAAEAAwAAAAAAAAAEAMwBaAeQBhgAdAHQAsBkvtBMEACsEK7ITGQors0ATFgkrsAQvtAoEACsEK7IECgors0AEBwkrAbAeL7AH1rQGBQARBCuwBhCxFQErtBYFABEEK7EfASuxBgcRErAIObAVEbEKGTk5ALETGRESsBw5sAQRsQEQOTmwChKwDTkwMT8BJyYjIgcjPgEzMh8BNzMHFxYzMjUzFAYjIi8BB5FPGBcULwY1BDcxGxsqO0FKGRwWMzU2MycqGTxajA8OTkZLEBlphg8RSzxTGhBsAP//ADQAJAIYAXQQCw32AkoB4cAA//8AMgBtAhYBvRAmDcoAqBAGDfAoRQAAAAEAKAAEAiAB5gAmAJgAsAMvsCUztAQEADcEK7AjMrIDBAors0ADAAkrsCAvtBcEACsEK7IXIAors0AXHAkrsAkvtA8EACsEK7IJDwors0AJDAkrAbAnL7AM1rQLBQARBCuwCxCxGgErtB0FABEEK7EoASuxCwwRErEBDTk5sBoRtwAFAgYPICMmJBc5ALEXIBESsQYiOTmwCRGwFTmwDxKwEjkwMTcjNyM1MzcnJiMiByM+ATMyHwE3MwcWMzI2PQEzFRQGIyInByEVIaZFO3SbVDcXFC8GNQQ3MRsbSjlASBkTGxg1OTAjKEEBGf7ABGlGlSQOTkZLECxlgg0hJQUQOkUWdkYA//8AMgAkAhYCGBAmACAAtRAHDfAAKACgAAIAMv/tAhYCGAATACwAvgCyAQAAK7IaAQArtBQEACsEK7IUGgors0AUFwkrtAMEARoNK7AQM7QDBAA3BCuwEjK0BwgBGg0rsAwztAcEADcEK7AOMrIIBwors0AICgkrtB8oARoNK7QfBAArBCuyHygKK7NAHyQJKwGwLS+wF9a0FgUAEQQrsBYQsSIBK7QlBQARBCuxLgErsRYXERKwGDmwIhFADAEFAgkLDA8GExAaKCQXOQCxHygRErAqObAUEbEdKzk5sBoSsBw5MDEXIzcjNTM3IzUhNzMHMxUjBzMVIQMiByM+ATMyHwEWMzI2PQEzFRQGIyIvASbbRSGFrj3rARUdQx2MtTzx/uVGLwY1BDcxGxt1HRUbGDU5MCcqYhcTN0ZmRjExRmZGAbFORksQRREhJQUQOkUaPw4AAAAAAQAyAAQCFgIgAC4AtwCyEwEAK7QNBAArBCuyDRMKK7NADRAJK7ITDQors0ATFwkrsAMvsC0ztAQEADcEK7ArMrIDBAors0ADAAkrsAcvsCkztAgEADcEK7AnMrAkL7QbBAArBCuyGyQKK7NAGyAJKwGwLy+wENa0DwUAEQQrsA8QsR4BK7QhBQARBCuxMAErsQ8QERKyAgEROTk5sB4RQAsFAAkGChMkJyorLiQXOQCxGyQRErEKJjk5sA0RsRYZOTkwMTcjNyM1MzcjNTM3JyYjIgcjPgEzMh8BNzMHFjMyNj0BMxUUBiMiJwczFSEHIRUhpkUQP2M1mLxAThcULwY1BDcxGxtgKUA2CwkbGDU5MBcaMub+9zQBPf6gBCBGZkZ/Mg5ORksQOFBrAyElBRA6RQpiRmZGAAAA//8AHwBwAdIB5hAmDfAAohAGDfD+bgAAAAEAIQAsAdQCDgA6AM4AshsBACuwNy+0LgQAKwQrsi43CiuzQC4zCSuwBC+0CgQAKwQrsgQKCiuzQAQHCSuwKC+0HwQAKwQrsh8oCiuzQB8kCSuwES+0FwQAKwQrshEXCiuzQBEUCSsBsDsvsAfWsBQytAYFABEEK7ATMrAGELExASuwIjK0NAUAEQQrsCQysTwBK7EGBxESsQEIOTmwMRFACwACCg4RFxwdKCs3JBc5ALEuNxESsDo5sAQRsAI5sAoSsQ0rOTmxHygRErEOKjk5sBERsRodOTkwMTcjNyYjIgcjPgEzMh8BNycmIyIHIz4BMzIfATczBxYzMjY9ATMVFAYjIicHFxYzMjY9ATMVFAYjIi8BlEVcFAovBjUENzEbGwU1SRcULwY1BDcxGxtdPkBMDQsbGDU5MBoeNT4dFRsYNTkwJyo9LKMITkZLEANfLw5ORksQN2+KBCElBRA6RQ1gJBEhJQUQOkUaJwD//wAyAAACFgI5ECYN+zJTEAcNygAA/zv//wAhADQB0gIxECYN8AARECcN8AAA/2YQBw3wAAAAuf//ADIAMAIWAhoQJgAgAMEQBw3xACgAogACABsAMwIQAdIAGgA1AG0AsAEvtA8EACsEK7IBDwors0ABFQkrsAcysCovtBwEACsEK7IcKgors0AcIwkrsDAyAbA2L7AI1rAwMrQHBQARBCuwMTKwBxCxFgErsCIytBUFABEEK7AjMrE3ASuxFgcRErMODykqJBc5ADAxJCIGBw4CByM+Ajc+ATIWFx4CFyMuAScuATI2Nz4CNzMOAgcOASImJy4CJzMeARcWAUNbWhsTERABIwIZIB4aWltaGh4gGQEiAhgbG7VaWxsTERABIgEZIB4aW1paGh4gGQIjARgcG5MSDAkLGhQrNRkODBERDA4ZNSsdGA0M8RIMCQsaFCs1GQ4MEREMDhk1Kx0YDQwAAP//ADIAbwIWAiAQJgAgAAAQBw5XAI8Adf//ADL/uwIWAg0QJgAgAAMQJwB5AJ0AwhAHAHkAnf7Y//8AMv+4AhYCDhAmACAAAxAnAHn/2wDDEAcAeQFX/tX//wAy/74CFgIMECYAIAADECcAeQFXAMEQBwB5/9v+2///AC//xAKtAgwQJwAgAJcAAxAnAHn/2ADBEAcAef/Y/uEAAP//ADL/wgLBAgwQJgAgAAAQJwB5AgIAwRAHAHkCAP7f//8AMgByAhYCnxAmACAAAxAGAn19mwAA//8AMgByAhYCbhAmACAAAxBHDnUAAgElOFRAAP//ADIAcgIWAqUQJgAgAAMQDw3fAJwBxSAAAAD//wAyAHICFgKnECYAIAADEA8N4ACMAccgAAAA//8AMgByAhYC5hAmACAAAxAHDlgAOAE0//8AMgByAhYDBBAnD17/2ADyEAYAIAAD//8AMgByAhgC5xAmACAAAxAvAEcAKAG/GZkQLwBIAOwBwBmZEA8ASQGvAcEZmQAA//8AMgByAhYCxhAmACAAAxAPAFAAZAHDHrgAAP//ADIAcgIWAusQJgAgAAMQDwAiAKEBhx64AAAAAQAy/+wCFgHYABMAPACyBAAAK7AGL7ABM7QHBAA3BCuwADKwCi+wETO0CwQANwQrsA8ysgsKCiuzQAsNCSsBsBQvsRUBKwAwMSUVIQcjNyM1MzcjNTM3MwczFSMHAhb+/jZLNpe0Kt77M0sznrsqtUaDg0ZmRnd3RmYA//8AMgBZAhYBwRAmDcoAlBAmDcoAJRAHDcoAAAC2AAAAAQAo/+wCIAIgABsATACyBAAAK7AGL7ABM7QHBAA3BCuwADKwCi+wGTO0CwQANwQrsBcysA4vsBUztA8EADcEK7ATMrIPDgors0APEQkrAbAcL7EdASsAMDElFSEHIzcjNTM3IzUzNyM1ITczBzMVIwczFSMHAiD+0y5LLoCdIL3aIPoBFyhLKJazINPwIJ9GbW1GS0ZLRl9fRktGSwAA//8APP/IAiACDBAnDcoACgEBECYNygpXECYNygqtEAcNygAK/wMAAP//ADL/9QIbAn8QJw3KAAD/MBAHAB8ABQClAAD//wAy//UCHQJ/ECcNygAH/zAQBwAhAAAApQAA//8AMv+GAh4CmBAnAB8ABQC+EAcAIAAI/xcAAP//ADL/hAIbAp8QJwAgAAD/FRAHACEAAADFAAD//wAt//cDjwHaECcAHwF5AAAQBgAfAAD//wAt//cDjwHaEA8OGAO8AdHAAAABABv/7AIQAiAAPwBoALIhAAArsDAvtD0EACsEK7I9MAors0A9NgkrsAgyAbBAL7Ap1rA2MrQoBQARBCuwNzKwKBCxFwErsAgytBYFABEEK7AJMrFBASuxFygRErMPEC8wJBc5ALEwIRESsBA5sD0RsA85MDEBMwc2Nz4CNzMOAgcGDwEWFx4CFyMuAScuASMiIwcjNwYHDgIHIz4CNzY/ASYnLgInMx4BFx4BMzIzAWxLRSsbExEQASIBGSAeJT8mVTUeIBkBIgIYGxtaLQMDRktDMR4TERABIwIZIB4oRCZaOB4gGQIjARgcG1otBwcCIKUJDAkLGhQrNRkOEQhcBBgOGTUrHRgNDBKnnwgOCQsaFCs1GQ4SCFoDGg4ZNSsdGA0MEgAAAAIALf/sAhYCIAAPABIAFACyDgAAK7ALMwGwEy+xFAErADAxNzUlNzMHNxUPARcVJwcjPwIHLQEmQEswaI9K2fUwSzscL6DGRXyZcixPO7BaT2hzjkFwQQACAC3/vAIWAfAADwASABEAsgkAACsBsBMvsRQBKwAwMQEzBxcVBQcjNwc1PwEnNR8BBzcBWUtAsv7dPEssa5NJ3PclLpwB8JlMRXuPaC1PPa5aT2hbbkEAAgAt/7ICFgKyABcAGgApALIUAAArsA8ztBUEACsEK7ANMrIUFQors0AUEQkrAbAbL7EcASsAMDETNSU3Mwc3FQ8BFxUnByEVIQcjNyM1Mz8CBy0BHjpLKnCXSeD7WAFT/pAcSxwuS2McLZgBa0V5iWIvTz6qXU9qzkNDQ0PpQmo+AAAAAgAt/7ICFgKyABcAGgApALIKAAArsAUztAsEACsEK7ADMrIKCwors0AKBwkrAbAbL7EcASsAMDEBFQ8BIRUhByM3IzUzNwc1PwEnNQU3Mw8CNwIW/1QBU/6QHEscLktEj7c+9QERR0tSHCR5AbBFbMdDQ0NDoT1PS5RmT3SnwkFUMQD//wAy/9QCGwJ/ECcN8AAe/wYQBwAfAAUApQAA//8AMv/UAhsCfxAnACEAAAClEAcN8AAe/wYAAP//ADL/OgIeAoEQJwAhAAP/QxAHAB8ABQCnAAD//wAy/zkCHgKBECcAHwAF/0IQBwAhAAMApwAAAAEALf/3AhYB2gAOACkAsgwAACuwAC+0AQQAKwQrAbAPL7EQASsAsQAMERKwCzmwARGwCDkwMTc1MiQ3FQ4BBx4BFxUmJC18AQBtVHFna3hJZv74xkVzXE9MQBUWREpPWnUAAP//AC3/9wIWAdoQDw4jAkMB0cAA//8AMf//AhoCWxAnDcoAAP86EAcOIwAEAIEAAP//ADL//wIdAlwQJw3KAAD/OhAHDiQABwCCAAD//wAt/7UCFgIrECYOIwBREAcN8AAP/uf//wAt/7UCFgImECYOJABMEAcN8AA4/ucAAgAt/9oCFgIOABYAGwBAALIQAAArsgQBACu0AAEQBA0rtAAEACsEKwGwHC+xHQErALEAEBESsg8SFTk5ObABEbIMFxg5OTmwBBKwCzkwMTc1Mj8BMwc2NxUGDwEeARcVJicHIzcmPwEGBxYtipdNSzY1MVw7ITNSM2B2R0tSb4sKGiIbxkVLuIAjKU9UHVAUPDRPVTepwykZGQcHBQAAAAIALf/aAhYCDgAWABsAQgCyDAAAK7IAAQArtAUEDAANK7QFBAArBCsBsBwvsR0BKwCxBQwRErIHCg85OTmwBBGyEBcYOTk5sAASsRMWOTkwMQEzBxYzFSIPASM3Bgc1Nj8BLgEnNRYfAQc2NyYBUEtbcWWMmUNLKzMuWjgjMlEyXnUkDB0kHQIO2SpFTZ9lISdPUR5TFDwzT1M3XRwICAYAAAAAAQA3AAACEgJYABQANgCyAAAAK7QSBAA3BCuyCwEAK7QIBAA3BCsBsBUvsAXWtA0FABsEK7EWASsAsQsSERKwBTkwMSEiLgI1NDY7ARUjBBUUHgI7ARUBfkZyXDOxlpSU/v8nSVg5jB9Ed1KXlUYH30JcMhZGAAD//wA3AAACEgJYEAsOKwJJAljAAAACADf/xQISArIAFgAbAPEAsgsAACu0CAQANwQrsgUBACuwGDO0AgQANwQrsBYysgIFCiuzQAIACSuwATIBsBwvsBLWtBoFABsEK7EdASuwNhq6PQXssQAVKwqwAC4OsA/ABbEBCPkOsA7ABbAOELMCDgETK7MFDgETK7o9BeyxABUrC7MGDgETK7MNDgETK7APELMQDwATKwWzFg8AEyu6PQXssQAVKwuzFw8AEysFsxgPABMrshAPACCKIIojBg4REjmwFzmyDQ4BERI5sAY5ALUGDQ4PEBcuLi4uLi4BQAwAAQIFBg0ODxAWFxguLi4uLi4uLi4uLi6wQBoBADAxATMHMxUjAxY7ARUjIicHIzcmNTQ2OwEDEwYVFAGfNxxYb44tPIyMRTkXNx2YsZYFn4jvArJaRv4/C0YPSlxEx5eV/gwBrQ3YlAAAAAIAN/++AhICqwAVABoA8wCyCwAAK7EHCjMztAwEADcEK7ENFzIysgsMCiuzQAsICSuwCTKyEQEAK7QSBAA3BCsBsBsvsBnWtAQFABsEK7EcASuwNhq6PQXssQAVKwqwCS4OsADABbEICPkOsAHAswIIARMrBbMHCAETK7AJELMKCQATK7MNCQATK7o9BeyxABUrC7MOCQATK7MVCQATK7AIELMWCAETKwWzFwgBEyuyDgkAIIogiiMGDhESObAVObIWCAEREjmwAjkAtQABAg4VFi4uLi4uLgFADAABAgcICQoNDhUWFy4uLi4uLi4uLi4uLrBAGgEAsREMERKwBDkwMQEzBxYVFAYjByM3IzUzEyYrATUzMh8BAzY1NAFuNyWSsJUVNxVfdY0uQIyMSToch+kCq3ZGw5aWQkJGAb8NRhFV/lUQ1ZAAAAD//wAk/+oCEgK6ECcNyv/y/yUQBg4rAGL//wAy/+sCFgK3ECYOLABfEAcNygAA/yYAAgAy/7ECFgLuAB4AJAB/ALIGAAArsAEztAcEADcEK7AAMrIGBwors0AGAwkrsBsvtBgEADcEK7AhL7AUM7QOBAA3BCuwEjKyDiEKK7NADhAJKwGwJS+wC9a0IwUAGwQrsgsjCiuzQAsGCSuxJgErsSMLERKxBAU5OQCxGBsRErEJHTk5sCERsQsfOTkwMSUVIQcjNyM1MzcmNTQ2OwE3MwczFSMDFjsBFSMiJwcnEyMEFRQCFv6fGksaOFcserGWKxdLFx4+yDBCjIxQPx8Cuwv+/zBGOTlGYkqyl5U0NEb+Qg5GFEajAaEH34QAAAAAAgAy/7ECFgLuAB0AIgB2ALIPAAArsAoztBAEADcEK7AIMrIPEAors0APDAkrsBMvsAcztBQEADcEK7AZL7QaBAA3BCsBsCMvsCHWtAQFABsEK7IEIQors0AECgkrsSQBK7EEIRESsAE5ALEUExESsAY5sBkRswIEHh8kFzmwGhKwHTkwMQEzBxYVFAYPASEVIQcjNyM1MzcjNTMTJisBNTMyHwEDNjU0AbxLQEeiixUBSv6XGksaME8VY4K9PW6MjHlPF6PFAu6QS4iQlQYvRjo6Ri5GAaQoRi10/pQdxFYAAAAAAgAo/+8C3AHsAAwAHQBPALISAAArtBoEADcEK7ACL7QMBAATBCsBsB4vsBTWtBcFABsEK7AXELEdASu0DwUAGwQrsR8BK7EdFxESswAHERIkFzkAsQIaERKwBTkwMQEVIRYXByYnNjcXBgclMxUUBiAmPQEzFRQWMzI2NQIv/vUhUhhDZmZDGFIhAXBIzP7kzEisZmSuAUsmIWYYUWFhURhmIaG0g8bGg7S+YpeYYf//ACj/7wLcAewQJg3iAAAQBg3RXAcAAP//ACj/7wLcAe0QJg3iAAAQBwJ5AOIARwABADQACAIsAfoABwA4ALABL7QGBAA3BCuwBS+0AgQANwQrAbAIL7AB1rQGBQAbBCuyBgEKK7NABgAJK7ADMrEJASsAMDElIREhFSERIQIs/ggB+P5NAbMIAfJH/p0AAP//AFAAAQJIAfMQDw42AnwB+8AA//8AQgACAjoCiBAnDcoAGv89EAcONgAOAI4AAP//AEIAAAI6ApQQJw3KABr/OxAHDjf/8gChAAD//wBFAAECNwH5EIcONgA9Ai0AAMAAQAAAAAAA//8ARQABAjcB+RAPDjoCfAH6wAD//wAr//EC3QKjECYYVgAAEAYADmRpAAD//wAr//EC3QKjECYNyl1kEAYYVgAAAAAABQAr//EC3QKjAAcADQATABkAHwBiALIHAAArtB4EABMEK7ASL7QDBAATBCsBsCAvsAHWtAoFABEEK7AKELEYASu0BQUAEQQrsSEBK7EYChESQAoDBgcCDQ4QFRocJBc5ALESHhESQAoBBAUADAgPFBYbJBc5MDE2EDYgFhAGIAMGFRQXNycXNyYjIgUHFzY1NAMnBxYzMivKAR7Kyv7iU0JEuZS7vFJqagFMu7lEa7m5UWhpuwEeysr+4soCElFoalG54ry8RGu7uVFqaP63ubpCAAADACv/8QLdAqMAAwALABMAXgCyEwAAK7QHBAATBCuyAwEAK7ALL7QPBAATBCsBsBQvsA3WtAUFABEEK7AFELEJASu0EQUAEQQrsRUBK7EJBREStQACDg8SEyQXOQCxAwcRErYBBAkMDRARJBc5MDEJAScBBBQWMjY0JiICEDYgFhAGIAJI/qAmAWD+Pqvyq6vy4MoBHsrK/uIB5/6gJgFgSvKrq/Kr/k0BHsrK/uLK//8AK//xAt0CoxAnDlcA5v/nEAYYVgAA//8AK//xAt0CoxAvDdAAoQBqOZkQBhhWAAAAAP//ACv/8QLdAqMQJhhWAAAQBwANAMD/FP//ACv/8QLdAqMQJhhWAAAQDwAgAMEAsyo9AAD//wAr//EC3QKjECcAEADhADwQBhhWAAAAAQBM//8CcQIiAAcAPgCyBgAAK7AEL7QBBAA3BCuyAQQKK7NAAQcJKwGwCC+wBta0BQUAGwQrsAAysgUGCiuzQAUDCSuxCQErADAxExUhFSEVIxGSAd7+IkYCIuRG+AIiAAAA//8AH///AkQCIhAPDkUCkAIhwAAAAQAP/8oCjAJsAAcARACwBS+wADO0BgQANwQrsgUGCiuzQAUDCSsBsAgvsAPWtAIFABsEK7ICAwors0ACAAkrsgMCCiuzQAMFCSuxCQErADAxASERIxEhNSECjP7kRv7lAn0CJv2kAlxGAAAAAQAPAAACjAKiAAcARgCyAgAAK7QDBAA3BCuwADKyAwIKK7NAAwUJKwGwCC+wBNa0BwUAGwQrsgcECiuzQAcBCSuyBAcKK7NABAIJK7EJASsAMDElFSE1IREzEQKM/YMBG0ZGRkYCXP2kAAAAAQBMAAABwAIiAAcAPgCyBgAAK7AEL7QBBAA3BCuyAQQKK7NAAQcJKwGwCC+wBta0BQUAGwQrsAAysgUGCiuzQAUDCSuxCQErADAxExUhFSEVIxGSAS7+0kYCIuRG+AIiAAAAAAEATP/sAdQCJAALAE0AsgoAACuwCC+0BQQANwQrsAQvtAEEADcEK7IBBAors0ABCwkrAbAML7AK1rQJBQAbBCuxAAQyMrIJCgors0AJBwkrsAIysQ0BKwAwMRMVIRUhFSEVIRUjEZIBQv6+AUL+vkYCJKBGcEacAjgAAAABAEz/7AKwAiQACwBNALIKAAArsAgvtAUEADcEK7AEL7QBBAA3BCuyAQQKK7NAAQsJKwGwDC+wCta0CQUAGwQrsQAEMjKyCQoKK7NACQcJK7ACMrENASsAMDETFSEVIRUhFSEVIxGSAh794gIe/eJGAiSgRnBGnAI4AAAAAgA+AAYCPgH8AAMABgAWAAGwBy+wBNa0AAUAGwQrsQgBKwAwMS0BNSUDEQUCPv4AAgBI/tUG8RTx/n0BEooAAAIAPgAGAj4B/AADAAYAFgABsAcvsADWtAQFABsEK7EIASsAMDE3EQUVBS0BPgIA/kgBK/7VBgH28RR+iIoAAP//AD4AIQI+Ao4QJw3KABn/XBAHDkwAAACSAAD//wA+ACUCPgKTECcNygAW/2AQBw5NAAAAlwAA//8AFAAtAjgCXxAnDcoABP9oEAcN4P/2AJ8AAP//AB4AAAJCAlQQJw3KAAsBSRAGDd8AAP//ABIAAAI2AmQQJw3KAAQBWRAGDeD0AAABAB4AAALKApwABgAUALIBAAArsAMzAbAHL7EIASsAMDEhIwMBIwEzAspY/P8AWAFNEQIA/gECmwAAAP//AB4AAALKApwQDw5TAugCnMAA//8APf/dAr8DHBAPDlYC/ALKwAAAAQA9/64CvwLtABMAQQCwBC+xDgTpsg4ECiuzQA4SCSuwCTIBsBQvsAjWtAsFADwEK7ALELERASu0AAUAPAQrsRUBK7ERCxESsAQ5ADAxJRQOASMiLgE1ETMRFBYzMjY1ETMCv02WXF6YTVKXWWGNUuhMjmBgjkwCBf33WIuQUwIJAAAAAQBXAS4A0wGrAAoALgCwBS+0AAQAEAQrtAAEABAEKwGwCy+wCNa0AwUAGQQrtAMFABkEK7EMASsAMDETMhYUBiMiJjU0NpQZJiQbGSQmAaslNCQlGRcoAAEAQABtAZYBsgAJACEAsAgvsAYztAIEAAcEKwGwCi+xCwErALECCBESsAc5MDETMzcXMwcXJwc3QIIpKYJqKGlpKAE2fHxMfU1NfQADAD4ABgKIAfwAAgAIAAsAMQABsAwvsAPWtAAFABsEK7AAELEJASu0BwUAGwQrsQ0BK7EJABESswEFCAskFzkAMDE/AScDEQUlESUXNQeGmppIASUBJf7b3ZqSb2v+mgH2zs7+Cs5C2msAAP//ADIAnAIWAdsQJg3KANcQBg3xMGMAAP//ADIADgIVAfcQhw4jAgz/4QAAQADAAAAAAAD//wAzABQCFgH9EIcOIwA8AioAAMAAQAAAAAAA//8ALQAVAhoB+BAmAB8AHhAHDlcBR/+a//8AGgAWAgcB+RAPDl0CNAIOwAD//wAwAAEElAHkECYAHwMKECcAHwFCAAoQBwAfAn4ACv//ACEAAQSFAeQQDw5fBLUB5cAAAAIAKP/IAiACiAAeACMARwCyFgAAK7ARM7QXBAA3BCuwDzKyFhcKK7NAFhMJK7AbL7QcBAArBCsBsCQvsSUBKwCxGxcRErELDjk5sBwRsggfIDk5OTAxATMHNjcVBg8BHgEXFSYnByEVIQcjNyM1MzcmIzUyNwc3BgcWAaNLNTMuXDokNFMzYXhWATX+rBlLGVl4Ym5ji5g1CxshGgKIdSEnT1MeUBM9NE9WN8BGNzdG2ihFTHgZBwcFAAAAAgAo/8gCIAKIAB8AJABFALIPAAArsAoztBAEADcEK7AIMrIPEAors0APDAkrsAUvtAQEACsEKwGwJS+xJgErALEFEBESsBg5sAQRshkgITk5OTAxATMHFjMVIg8BIRUhByM3IzUzNwYHNT4BPwEuASc1Fh8BBzY3JgFtS2BoXYOQVQFr/nYZSxkjQj08NzVJKR45VjZmfiMIFRgUAojXJEVEv0Y3N0aIJi5PMDYTQxQ+N09aOFkSBQUEAAACAEL/uAI6Au4AFwAbAHkAsBEvsAwztBIEADcEK7AKMrIREgors0ARDgkrsBQvsAgztBsEADcEK7AGMrAaL7AEM7QWBAA3BCuwAjKyFhoKK7NAFgAJKwGwHC+wFdawETK0GwUAGwQrshsVCiuzQBsICSuxAwsyMrEdASuxGxURErEPEDk5ADAxATMHMxUjAyEVIQchFSEHIzcjNTM3IxEhAxMhEQHoSzM6XrQBEv7KJwFd/n8lSyUsUCd3AXPYtP72Au5mR/6dSE5GSkpGTgHy/lYBY/6dAAACAEL/uAI6Au4AFwAbAHsAsgYAACuwATO0BwQANwQrsAAysgYHCiuzQAYDCSuwCi+wFTO0CwQANwQrsBkysA4vsBgztA8EADcEK7ATMrIPDgors0APEQkrAbAcL7Aa1rQVBQAbBCuwADKyGhUKK7NAGg4JK7EGCjIysR0BK7EVGhESsRITOTkAMDElFSEHIzcjNTM3IzUzEyE1ITczBzMRIQcBAzMRAjr+fiRLJCtPLn2hs/6sAXktSy00/tAuAQWzx0ZGSEhGXEcBY0haWv4OXAIG/p0BY///ADL/QgIbAlQQJw30ABT+6BAGAB8Fev//ADL/QgIbAi0QJgAhAFMQBw30AAr+6P//AC3/QgIWAioQJw30AAD+6BAGDiMAUP//AC3/QgIWAiYQJw30AAD+6BAGDiQATP//AFIALAC6Ay8QJwB5//sAlxAnAHn/+/9JEAcAef/7AeQAAP//AIEA/wODAWcQJgB5KhwQJwB5AsQAHBAHAHkBdQAc//8AgQAtA4IDLxAnAHkAKv9KECcAeQF2AJcQBwB5AsMB5AAA//8AgAAsA4IDLxAnAHkBdgCXECcAeQLD/0kQBwB5ACkB5AAAAAMAJ//oAw0CzwAHAA8AIwB/ALIaAAArshcAACu0AwQAHwQrsAsvtCEEAB8EK7AQMgGwJC+wHta0DgUAEQQrsA4QsQYBK7QUBQARBCuwETKxJQErsQ4eERKwGjmwBhG3AQkSFxkcISMkFzmwFBKwEDkAsQMXERKwGzmwCxG3AAgSFBkcHiMkFzmwIRKwETkwMQkBFjMyNjU0CQEmIyIGFRQBFwcWFRQGIyInByc3JjU0NjMyFwKK/kpWdIG3/dkBt1dxgbcCgiRbXNeYi2ZhJWFZ15iIaAIq/kZKt4F1/sMBt0m3gXEB4iNbZ4yY11tiJWJmiZjXWQAAAQBiAAABfgLZAAUAMgCyBQAAK7IAAwArtAMEADcEKwGwBi+wBda0BAUAGwQrsgQFCiuzQAQCCSuxBwErADAxEyEVIxEjYgEc1kYC2Ub9bQABAEgAAAFlAtkABQAyALICAAArsgUDACu0BAQANwQrAbAGL7AC1rQBBQAbBCuyAgEKK7NAAgQJK7EHASsAMDEBESMRIzUBZUbXAtn9JwKTRgAAAP//AEoAAAFmAtkQDw5uAcgC2cAA//8AYgAAAX8C2RAPDm8BxwLZwAAAAQAoAFYCIAF3AAUANgCwAi+0BQQANwQrsgIFCiuzQAIECSsBsAYvsATWtAMFABsEK7IDBAors0ADAQkrsQcBKwAwMQEVIRUjEQIg/k5GAXdG2wEhAAAAAAEAlv84AXYDhAANACIAsAkvsQQE6QGwDi+wANaxDQXpsQ8BKwCxBAkRErAGOTAxFxE0NjMyFxUmIyIGFRGWZEgXHSIXITHIA39acwVTB0JM/JMA//8ACv84AOoDhBAPDnMBgAK8wAAAAQA7AJ4CWAFJAAwAEwCwAC+xBwTpAbANL7EOASsAMDElIgcwNT4BMzIWFxUmAUu3WTmAVVaAOVn3WUA5MjI5QFkAAP//ADsAmwJYAUYQDw51ApMB5MAAAAEAGf86AToC6gAFABYAAbAGL7AE1rQABQAHBCuxBwErADAxAQMTIwMTATri4jvm5gLq/ij+KAHYAdgAAAEAD/86ATAC6gAFACEAAbAGL7AE1rAAMrQCBQAHBCuxBwErsQIEERKwBTkAMDETMxMDIxMPO+bmO+IC6v4o/igB2AAAAQAo/zgBVAMOAAsAFgABsAwvsAXWtAQFADwEK7ENASsAMDEBBgIdASM1EDc+ATcBVF97UkooUjoDDoX+gdz28wEGvmKGNwAAAQAo/zgAegMgAAMAHQABsAQvsAPWtAIFADwEK7QCBQA8BCuxBQErADAxEzMRIyhSUgMg/BgAAAABACj/SgFUAyAACwAWAAGwDC+wBta0CQUAPAQrsQ0BKwAwMQUjLgEnJhE1MxUUEgFULjpSKEpSe7Y3hmK+AQbz9tz+gQAAAP//ACz/OAFYAw4QDw57AYACWMAA//8BBv84AVgDIBAHDnoA3gAAAAD//wAs/0sBWAMhEA8OeQGAAlnAAAABAFj/OAFNA04ABQAzALAFL7ECBOmyBQIKK7NABQEJKwGwBi+wAda0AAUAJgQrsgABCiuzQAAECSuxBwErADAxFyMRMxUjpEz1qcgEFkwAAAEAWP84AKQDIAAEAB0AAbAFL7AC1rQBBQAmBCu0AQUAJgQrsQYBKwAwMRMRIxEwpEwDIPwYA+gAAQBY/wkBTQMgAAYANgCwBS+xAgTpsgIFCiuzQAIGCSsBsAcvsAXWtAIFACYEK7AAMrICBQors0ACBAkrsQgBKwAwMRMwETMVIxGkqfUDIPw1TAQXAAAA//8AN/84ASwDTxAPDoEBhAJYwAD//wDg/zgBLAMgEAcOgACIAAAAAP//ADf/CgEsAyAQDw5/AYQCWMAAAAEAef84ARQC4wALADgAsgsDACu0AgQAKwQrsgILCiuzQAIGCSsBsAwvsAfWtAYFACYEK7IGBwors0AGAAkrsQ0BKwAwMQEVIyIGFREjETQ2MwEUDyUaTTk0AuNBHCf82QMoPkUAAAAAAQAy/zgAzQMgABEAHAABsBIvsAjWsBAytAcFACYEK7AAMrETASsAMDETFRQGBxYVESMRNCYnNT4BPQHNJC5STSIsLCIDILZFRhImeP4JAehFPAlFCTtGpwAAAAABAIAAAQEbAyAACwA2ALABL7QKBAArBCuyCgEKK7NACgYJKwGwDC+wBNa0BwUAJgQrsgcECiuzQAcACSuxDQErADAxJSMiJjURMxEUFjsBARsuNDlNGiUPAUU+Apz9ZSccAAAAAQCA/zgAzQMgAAMAHQABsAQvsAHWtAAFACYEK7QABQAmBCuxBQErADAxFyMRM81NTcgD6AAAAAABADL/OADNAuMACwA4ALIAAwArtAsEACsEK7ILAAors0ALBgkrAbAML7AG1rQFBQAmBCuyBgUKK7NABgAJK7ENASsAMDETMzIWFREjETQmKwEyLjQ5TRolDwLjRT782AMnJxwAAQCA/zgBGwMgABEAHAABsBIvsAvWsAAytAoFACYEK7ABMrETASsAMDETMxUUFhcVDgEVESMRNDcuATWATSIsLCJNUi4kAyCnRjsJRQk8Rf4YAfd4JhJGRQAAAAABADIAAQDNAyAACwA2ALAAL7QBBAArBCuyAQAKK7NAAQYJKwGwDC+wBda0CAUAJgQrsgUICiuzQAUACSuxDQErADAxNzUzMjY1ETMRFAYjMg8lGk05NAFBHCcCm/1kPkUAAAAAAQCW/zgA6gMgAAMAFwABsAQvsAHWsQAF6bEABemxBQErADAxFyMRM+pUVMgD6AAAAQA4/zgC7QLaAAYAIACyAAMAK7QDBAAqBCsBsAcvsQgBKwCxAAMRErAGOTAxEyEVIQEjATgCtf3VAVCC/qgC2mD8vgNKAAAAAQA4/34C7QMgAAYAHgCwAC+0BAQAKgQrAbAHL7EIASsAsQQAERKwATkwMRc1ATMBIRU4AViC/rACK4JYA0r8vmAAAP//AED//wLfAq4QLwAxACUBthXCEC8AOAEpANYVwhAPAC8CKQAAFcL//wAzAAAC3gKxEC8ANgAjAbQVwhAvADIA9wDaFcIQDwArAgQAABXC//8AMwAAAt4CsRAvADcBLADXFcIQLwA7AgQAABXCEA8ANgAjAbQVwv//AEQAAALeAq8QLwAoACkBthXCEC8ANwEsANcVwhAPADsCBAAAFcL//wBE//8C3wKvEC8AKAApAbYVwhAvADIBBgDaFcIQDwA3AhL//xXC//8AOv/uAuoCrxAvADQB7QACFcIQLwAxAQMA1hXCEA8AKAAfAbYVwv//ADQAAALSAq4QLwAkADABtRXCEC8AJgESANoVwhAPAC4B8gAAFcL//wA9//8C1QKuEC8AJQAiAbUVwhAvACgBHQDYFcIQDwAvAh8AABXC//8A0wBgAm4CcBAvADYBmgBoFcIQDwAlALgBdxXCAAD//wC6AGUCiQJvEC8AKwCfAXYVwhAPADcBvABlFcIAAP//AN0AZAJoAnEQLwAvAMIBeRXCEA8AKQGmAGQVwgAA//8AvgBkAokCcBAvADcBvABkFcIQDwA5ALkBeBXCAAD//wDmAGQCXgJwEC8AKQGcAGQVwhAPACkAywF3FcIAAP//ALsAZgJ+Am8QLwAmAK4BchXCEA8ANQGbAGYVwgAA//8A2ABiAngCcRAvADYAyAF0FcIQDwA2AaQAahXCAAD//wDdAGQCAgJvEC8ANgDNAXIVwhAPACwBwABkFcIAAP//AEwAAALSAq0QLwAoAgUAABXCEC8ALwEsAN4VwhAPACcAMQG0FcL//wBWAAACjwKtEC8AJwA7AbQVwhAvACYBJgDaFcIQDwAUAhkAABXC//8AVgAAAscCrRAvACcAOwG0FcIQLwAmASYA2hXCEA8AFQIZAAAVwv//AFb//AK3Aq0QLwAnADsBtBXCEC8AJgEmANoVwhAPABYCCwAEFcL//wBWAAECyQKtEC8AJwA7AbQVwhAvACYBJgDaFcIQDwAXAhgAARXC//8AQAAAAtICrhAvACQA+gDdFcIQLwAuAfIAABXCEA8AMQAlAbYVwv//AEf//wLKArEQLwAxAewAABXCEC8ANgA3AbQVwhAPADwBFwDaFcL//wBOAAACzQKvEC8AKAAzAbYVwhAvADcBLADXFcIQDwAlAfgAABXC//8APf//AtkCsBAvACYAMAGzFcIQLwAkAQwA3BXCEA8AMQH7AAAVwv//AMUAbAJ5AmgQLwAoAKoBbxXCEA8AMAF0AGwVwgAA//8ARP//AtcCsRAvADYANAG0FcIQLwA4AQsA1hXCEA8AJQIC//8Vwv//AFj/+QLlAq4QLwAoAD0BtRXCEC8ANgExANgVwhAPACYCAgABFcL//wDcAGECfQJwEC8AKQDBAXcVwhAPADYBqQBpFcIAAP//ALwAYAJ9Am0QLwA2AakAaBXCEA8AKgCvAXAVwgAA//8A5ABfAn0CcBAvADUAyQF3FcIQDwA2AakAZxXCAAD//wDMAGICfQJzEC8ANgGpAGoVwhAPADgAsQF7FcIAAP//ANsAYgJrAm4QLwA2AMsBcRXCEA8AMwGcAGIVwgAA//8AVv//AsoCrRAvACcAOwG0FcIQLwAoASUA3xXCEA8ALwIUAAAVwgACAAr/6QIeAtkACgAhAJIAshgAACuyFAAAK7EFBOmyHQMAK7IgAgArsg4BACuxAATpAbAiL7AZ1rAcMrQMBQA8BCuxAh4yMrIZDAors0AZGwkrsBkQtBcFACYEK7IXGQors0AXIQkrsAwQsQgBK7ERBemxIwErsQgMERKxDhQ5OQCxAAURErIMERY5OTmwDhGwGjmwIBK0CxkbHB8kFzkwMQEiBhQWMzI2NTQmJxU2MzIWFRQGIyInFSMRBzU3NTMVNxUBLkJQUEJEVVPYOWloeHxoaztLPz9TQgHNb7hvb1lecH6GVpR/gp1aQwIfMkAyek4zQAAAAAEAEgAAAeIAuAAHAE4AsgQAACu0BQQACwQrsAIysgQAACu0BwQANwQrsgQAACu0BQQACwQrsAEyAbAIL7AE1rQHBQAbBCuwBxCxAAErtAMFABsEK7EJASsAMDElNTMVITUzFQGbR/4wSEhwuLhwAP//AG0AAAKxAroQLwAxAEYBTSAAEA8ALwGmAAEgAAAAAAMAAAAAAyADIAADAAcACwAUALILAAArsAMzAbAML7ENASsAMDE3ARcBJwEXAQcBFwG+Akcb/braAkcb/bocAwUb/PwaAkgZ/bfYAkgZ/bekAwYZ/PkAAAACALEAAAJhAuUAGwAfAG0Ash8AACu0HAQAHQQrsgMDACuxCgTpsgoDCiuzQAoGCSsBsCAvsADWsQ0F6bANELEfASuwFTKxHgXpsBMysB4QsQcBK7EGBemxIQErsQ0AERKwGTmxHh8RErIDEQo5OTkAsQocERKxABQ5OTAxEzQ2MzIWFSM0JiMiBhUUHgMdASM1NC4DEzMVI7F0YWxvVThJOkYlNDUlWiU1NCWzWloCJVhod3NKUj8zIz0wMEIlNy8gOS0xSv5xaAAAAAADACP/8wLyAsIACAAUACEAoACyDwAAK7QcBAATBCuyCQIAK7QVBAATBCu0BgUPCQ0rtAYEABMEK7IFBgors0AFAwkrsgYFCiuzQAYACSsBsCIvsBLWtBkFABEEK7AZELEDASu0AgUAGwQrsgMCCiuzQAMFCSuwAhC0AAUAEQQrsAAvsAIQsR8BK7QMBQARBCuxIwErsQIAERKzCQ8VHCQXOQCxBRwRErMMEhkfJBc5MDEBMxEjESM1MjY3MhYVFAYjIiY1NDYXIg4BFRQWMzI2NTQmAYglPGE6Nw+R0dKVltLVmGScTL+Ih7/GAkz+KQFlKSGe1ZKV09OXlNEhYpJQicC/iI25AAADACP/8wLyAsIAHwArADoArACyJgAAK7QzBAATBCuyIAIAK7QsBAATBCu0Ah8mIA0rtAIEABMEK7QWDCYgDSu0FgQAEwQrAbA7L7Ap1rQwBQARBCuwMBCxEwErtA8FABsEK7APELEJASu0GQUAGwQrsBkQsTYBK7QjBQARBCuxPAErsQ8TERKxAgQ5ObAJEbcGFhwfICYsMyQXObAZErEBADk5ALEfAhESsAQ5sAwRtwYREhkjKTA2JBc5MDElFSEmNTQ3PgE1NCYjIgYVFBcjNTQ2MzIWFRQGBw4BBxMyFhUUBiMiJjU0NhciBwYVFBYzMjY1NCcuAQIa/t8Bc0cvMykoMAE9VEBCVz1aKRoLV5HR0pWW0tWYlmJUv4iHv2wrcqk0BwlRSy49Li05Ny0JBg4/U1RAOVA8HBkWAhnVkpXT05eU0SFsXHyJwL+Ij2MnLQAAAwAj//MC8gLCADIAPgBNAOIAsjkAACu0RgQAEwQrsjMCACu0PwQAEwQrtBAaOTMNK7QQBAATBCu0IiE5Mw0rtCIEABMEK7AnMrQGLjkzDSu0BgQAEwQrsi4GCiuzQC4BCSsBsE4vsDzWtEMFABEEK7BDELETASuwATK0FgUAEQQrsAAysBYQsSsBK7QJBQAbBCuwCRCwDSDWEbQdBQARBCuwHS+0DQUAEQQrsAkQsUkBK7Q2BQARBCuxTwErsSsWERJACQYLEBohMzk/RiQXOQCxIRoRErITDRY5OTmwIhG0CzY8Q0kkFzmwLhKxCSs5OTAxASM2Nz4BMzIWFRQHFhUUBiMiJjU0PwEUFxYzMjY1NCYrATUzMh4BMzI3NjU0JiMiBgcGNzIWFRQGIyImNTQ2FyIHBhUUFjMyNjU0Jy4BATY2AREQQCY9UERRVEM8UAE2DhkyKDM4MyEJBAkGAR8jHC0mHCgHBVqR0dKVltLVmJZiVL+Ih79sK3IBziwcHCFKOEcfG1c9TUQ0DAcLLBQkMScrLisBARcTLiYtGxcS4NWSldPTl5TRIWxcfInAv4iPYyctAAAEACP/8wLyAsIACgANABkAKACzALIUAAArtCEEABMEK7IOAgArtBoEABMEK7QGDBQODSuwADO0BgQAEwQrsAEysgYMCiuzQAYECSuyDAYKK7NADAgJKwGwKS+wF9a0HgUAEQQrsB4QsQQBK7ALMrQDBQARBCuwCTKyAwQKK7NAAwEJK7IEAwors0AEBgkrsAMQsSQBK7QRBQARBCuxKgErsQQeERK1CAwOFBohJBc5ALEMBhESsAc5sBoRtAsRFx4kJBc5MDEBFSMVIzUjNRMzEScHMwMyFhUUBiMiJjU0NhciBwYVFBYzMjY1NCcuAQIaSzjPzzg4l5cHkdHSlZbS1ZiWYlS/iIe/bCtyAR0ydnYyATT+zOXlAaXVkpXT05eU0SFsXHyJwL+Ij2MnLQAAAwAj//MC8gLCAB4AKgA5AMMAsiUAACu0MgQAEwQrsh8CACu0KwQAEwQrsgMBACu0AAQAEwQrtAwTJQANK7QMBAATBCu0BholAA0rtAYEABMEK7IaBgors0AaHgkrAbA6L7Ao1rQvBQARBCuwLxCxDwErsAAytBAFABEEK7EDHTIyshAPCiuzQBACCSuwEBCxFwErtAkFABsEK7AJELE1ASu0IgUAEQQrsTsBK7EXEBEStQYMHyUrMiQXOQCxGhMRErYPCRAiKC81JBc5sAYRsAQ5MDEBMxUjFTYzMhYVFAYjIiYnNx4BMzI3NjU0JiMiBgcjEzIWFRQGIyImNTQ2FyIHBhUUFjMyNjU0Jy4BAQ32yR9AQVNaRThGAy0BMCYuGBo0KiMvBy2DkdHSlZbS1ZiWYlS/iIe/bCtyAkkyhSxZR0xkQTgMJS4gJ0QuOCsnAYPVkpXT05eU0SFsXHyJwL+Ij2MnLQAABAAj//MC8gLCAB0AKQA1AEQAvwCyMAAAK7Q9BAATBCuyKgIAK7Q2BAATBCu0EiQwKg0rtBIEABMEK7QMHjAqDSu0DAQAEwQrtBwFMCoNK7QcBAATBCsBsEUvsDPWtDoFABEEK7A6ELEXASu0CAUAEQQrsCEysAgQsScBK7QPBQARBCuwASDWEbQABQARBCuwDxCxQAErtC0FABEEK7FGASuxAQgREkAJDBIcHiQqMDY9JBc5ALEeJBEStwgPFwotMzpAJBc5sQUMERKxAAE5OTAxAQcmJyYjIgYVFBc2MzIWFRQGIyImJyY1NDc+ATMyByIGFRQWMzI2NTQmAzIWFRQGIyImNTQ2FyIHBhUUFjMyNjU0Jy4BAggzBwcTKTE5ASBMO0xTPiVDEiEbE00rZW4pNjcqJi8vHpHR0pWW0tWYlmJUv4iHv2wrcgHoDiAMIF5RDQpEU0FFXCcfOW5iPCgx1j0uM0M8MTU/AUXVkpXT05eU0SFsXHyJwL+Ij2MnLQAAAAMAI//zAvICwgAKABYAJQCNALIRAAArtB4EABMEK7ILAgArtBcEABMEK7IKAQArtAAEABMEKwGwJi+wFNa0GwUAEQQrsBsQsQYBK7QFBQAbBCuyBQYKK7NABQIJK7AFELEhASu0DgUAEQQrsScBK7EGGxESsQAKOTmxIQURErQJCxEXHiQXOQCxCh4RErQFDhQbISQXObAAEbACOTAxEyEVDgEHIz4BNyM3MhYVFAYjIiY1NDYXIgcGFRQWMzI2NTQnLgHuAThTWRJEDm1N/qKR0dKVltLVmJZiVL+Ih79sK3ICSCp5x2li41ys1ZKV09OXlNEhbFx8icC/iI9jJy0AAAAABQAj//MC8gLCABYAIgAtADkASADaALI0AAArtEEEABMEK7IuAgArtDoEABMEK7QFKTQuDSu0BQQAEwQrtB0jNC4NK7QdBAATBCu0EBc0Lg0rtBAEABMEKwGwSS+wN9a0PgUAEQQrsD4QsQcBK7QmBQARBCuwJhCwGiDWEbQNBQARBCuwDS+0GgUAEQQrsCYQsSsBK7AgMrQCBQARBCu0EwUAEQQrsAIQsUQBK7QxBQARBCuxSgErsSsaERJADAQFCxAAIygpLjQ6QSQXOQCxIykRErECBzk5sB0RtQsAMTc+RCQXObAXErENEzk5MDEBFhUUBiImNTQ3NjcmNTQ2MzIWFRQHBiciBhUUFjMyNjU0JgciBhUUFjI2NTQmAzIWFRQGIyImNTQ2FyIHBhUUFjMyNjU0Jy4BAcpVVYJTLw8cSE48O0kpDlEmLi4lJjEuKyk0NlA0MSaR0dKVltLVmJZiVL+Ih79sK3IBbh1YPE5MPUMfCwkhSjVFRTc8HAm2LycmLzAlKC7YNCopNzYqLDIBbtWSldPTl5TRIWxcfInAv4iPYyctAAQAI//zAvICwgAbACcAMwBCAMkAsi4AACu0OwQAEwQrsigCACu0NAQAEwQrtBcDLigNK7QXBAATBCu0CSIuKA0rtAkEABMEK7QPHC4oDSu0DwQAEwQrAbBDL7Ax1rQ4BQARBCuwOBCxDAErtB8FABEEK7AfELABINYRtAAFABEEK7AAL7QBBQARBCuwHxCxBwErtBMFABEEK7ATELE+ASu0KwUAEQQrsUQBK7EHARESQAoJDxccIiUoLjQ7JBc5ALEJAxESsQABOTmxHCIRErYMEwcrMTg+JBc5MDElNxYzMjc2NwYjIiY1NDYzMhcWFRQHBiMiJicmEyIGFRQWMzI2NTQmJzIWFRQGIyImNTQ2FyIHBhUUFjMyNjU0Jy4BAQgxDzk0HBQDIU86SlNAVCgdRCc5HzUOC3MoLi4qKTQ2G5HR0pWW0tWYlmJUv4iHv2wrctUKRDgpaERTQURbTThplj0kGhYTAXs8Mzg9PS80RJbVkpXT05eU0SFsXHyJwL+Ij2MnLQAABQAj//MC8gLCAA0AFgAfACsAOgDeALImAAArtDMEABMEK7IgAgArtCwEABMEK7QGEyYgDSu0BgQAEwQrtB0cJiANK7QdBAATBCuyHB0KK7NAHBoJK7IdHAors0AdFwkrtAAOJiANK7QABAATBCsBsDsvsCnWtDAFABEEK7AwELEaASu0GQUAGwQrshoZCiuzQBocCSuwGRC0FwUAEQQrsBcvsBkQsQoBK7QQBQARBCuwEBCxFQErtAIFABEEK7ACELE2ASu0IwUAEQQrsTwBK7EVEBEStQAGICYsMyQXOQCxHBMRErcKEAIVIykwNiQXOTAxATIVFAcGIyInJjU0NzYXIhUUFjMyNTQlMxEjESM1PgE3MhYVFAYjIiY1NDYXIgcGFRQWMzI2NTQnLgEB4I4tJz05IjQqJz5ULipS/sopPFMsNpeR0dKVltLVmJZiVL+Ih79sK3ICU/mBODMqPZCCODQnxmRsxdEg/ikBYykBJ5nVkpXT05eU0SFsXHyJwL+Ij2MnLQABAAABBAPoAVQAAwAXALACL7EDBOmxAwTpAbAEL7EFASsAMDEBFSE1A+j8GAFUUFAAAAAAAQAAANwD6AF8AAMAHQCwAi+0AwQADQQrtAMEAA0EKwGwBC+xBQErADAxARUhNQPo/BgBfKCgAP//Acz/OAIcAyAQgw7AAyD/OAAAQADAAAAAAAD//wGk/zgCRAMgEIMOwQMg/zgAAEAAwAAAAAAAAAMAAAEEA+gBVAAEAAkADgBHALANL7QBAwYICyQXM7EOBOmxAAUyMrEEBOkBsA8vsA3WtAsFABAEK7ALELEIASu0BgUAEAQrsRABK7EICxESsQMAOTkAMDEBFTAjNSEVMCM1IRUwIzUCcfoCcX39En0BVFBQUFBQUAAAAAADAAAA3APoAXwABAAJAA4AUQCwDS+0AQMGCAskFzO0DgQADQQrsQAFMjK0BAQADQQrAbAPL7AN1rQLBQAQBCuwCxCxAwErtAEFAAgEK7ABELEIASu0BgUAEAQrsRABKwAwMQEVMCM1IRUwIzUhFTAjNQJx+gJxff0SfQF8oKCgoKCgAP//Acz/OAIcAyAQgw7EAyD/OAAAQADAAAAAAAD//wGk/zgCRAMgEIMOxQMg/zgAAEAAwAAAAAAAAAQAAAEEA+gBVAAEAAkADgATAEgAsBIvtgEDBggLDRAkFzOxEwTpsgAFCjIyMrEJBOkBsBQvsBLWsRAF6bAQELENASuxCwXpsRUBK7ENEBESswAFCAMkFzkAMDEBFTAjNSMVMCM1IRUwIzUhFTAjNQLup6anAu5U/MBUAVRQUFBQUFBQUAAAAAAEAAAA3APoAXwABAAJAA4AEwBdALASL7YBAwYICw0QJBcztBMEAA0EK7IABQoyMjK0CQQADQQrAbAUL7AS1rEQBemwEBCxCAErtAYFAAwEK7AGELEDASu0AQUADAQrsAEQsQ0BK7ELBemxFQErADAxARUwIzUjFTAjNSEVMCM1IRUwIzUC7qempwLuVPzAVAF8oKCgoKCgoKAAAP//Acz/OAIcAyAQgw7IAyD/OAAAQADAAAAAAAD//wGk/zgCRAMgEIMOyQMg/zgAAEAAwAAAAAAAAAEBzP84A+gBVAAFADMAsAQvsQEE6bIEAQors0AEAAkrAbAGL7AA1rQFBQAxBCuyBQAKK7NABQMJK7EHASsAMDEFESEVIREBzAIc/jTIAhxQ/jQAAAEBzP84A+gBfAAFADYAsAQvtAEEAA0EK7IEAQors0AEAAkrAbAGL7AA1rQFBQAxBCuyBQAKK7NABQMJK7EHASsAMDEFESEVIREBzAIc/jTIAkSg/lwAAAABAaT/OAPoAVQABgA2ALAGL7AEM7ECBOmyBgIKK7NABgEJKwGwBy+wAda0AAUADQQrsgABCiuzQAAECSuxCAErADAxBSMRIRUwIQJEoAJE/lzIAhxQAAAAAQGk/zgD6AF8AAUANgCwBC+0AQQADQQrsgQBCiuzQAQACSsBsAYvsADWtAUFAA0EK7IFAAors0AFAwkrsQcBKwAwMQURIRUhEQGkAkT+XMgCRKD+XAAA//8AAP84AhwBVBCDDswAyAMgAADAAEAAAAAAAP//AAD/OAIcAXwQgw7OAMgDIAAAwABAAAAAAAD//wAA/zgCRAFUEIMOzQDIAyAAAMAAQAAAAAAA//8AAP84AkQBfBCDDs8AyAMgAADAAEAAAAAAAP//AcwBBAPoAyAQgw7MAyD/OAAAQADAAAAAAAD//wHMANwD6AMgEIMOzgMg/zgAAEAAwAAAAAAA//8BpAEEA+gDIBCDDs0DIP84AABAAMAAAAAAAP//AaQA3APoAyAQgw7PAyD/OAAAQADAAAAAAAD//wAAAQQCHAMgEAsOzAPoAljAAP//AAAA3AIcAyAQCw7NA+gCWMAA//8AAAEEAkQDIBALDs4D6AJYwAD//wAAANwCRAMgEAsOzwPoAljAAAABAcz/OAPoAyAABwBBALAFL7ECBOmyBQIKK7NABQcJK7ICBQors0ACAAkrAbAIL7AH1rQGBQAxBCuwATKyBgcKK7NABgQJK7EJASsAMDEBMxEhFSERIwHMUAHM/jRQAyD+NFD+NAAAAAEBzP84A+gDIAAHAEQAsAUvtAIEAA0EK7IFAgors0AFBwkrsgIFCiuzQAIACSsBsAgvsAfWtAYFADEEK7ABMrIGBwors0AGBAkrsQkBKwAwMQEzESEVIREjAcxQAcz+NFADIP5coP5cAAAAAAEBpP84A+gDIAAJAFgAsAcvsQQE6bIHBAors0AHCQkrsgQHCiuzQAQDCSsBsAovsAnWtAgFADEEK7IICQors0AIBgkrsAkQsw0JAQ4rtAQFAA0EK7ELASsAsQQHERKxAQA5OTAxASMRMxEhFSERIwHMKKABpP40UAEsAfT+NFD+NAAAAAEBpP84A+gDIAAJAFgAsAYvsQME6bIGAwors0AGCAkrsgMGCiuzQAMBCSsBsAovsADWtAMFADEEK7IDAAors0ADBAkrsAAQsw0ACA4rtAcFAA0EK7ELASsAsQMGERKxAAk5OTAxAREzESEVIREjEQHMUAHM/lygASwB9P40UP40AfQAAAEBpP84A+gDIAAHAEEAsAcvsQQE6bIHBAors0AHAQkrsgQHCiuzQAQCCSsBsAgvsAHWtAAFAA0EK7ADMrIAAQors0AABgkrsQkBKwAwMQUjETMRIRUhAkSgoAGk/lzIA+j+NFAAAAAAAQGk/zgD6AMgAAkAVACwAi+wBTO0CQQADQQrsgIJCiuzQAIECSuyCQIKK7NACQgJKwGwCi+wBNa0AwUAMQQrsgMECiuzQAMBCSuwBBCzDQQGDiu0CQUADQQrsQsBKwAwMQEVIREjESMRMxED6P40UCigAXyg/lwBpAJE/lwAAAABAaT/OAPoAyAACQBUALAIL7QFBAANBCuwATKyCAUKK7NACAkJK7IFCAors0AFAwkrAbAKL7AC1rQFBQAxBCuyBQIKK7NABQcJK7ACELMNAgAOK7QJBQANBCuxCwErADAxBREzETMRIRUhEQGkKFABzP5cyAJEAaT+XKD+XAAAAAEBpP84A+gDIAAHAEQAsAUvtAIEAA0EK7IFAgors0AFBwkrsgIFCiuzQAIACSsBsAgvsAfWtAYFAA0EK7ABMrIGBwors0AGBAkrsQkBKwAwMQEzESEVIREjAaSgAaT+XKADIP5coP5cAAAA//8AAP84AhwDIBALDtwD6AJYwAD//wAA/zgCHAMgEAsO3QPoAljAAP//AAD/OAJEAyAQCw7fA+gCWMAA//8AAP84AkQDIBALDt4D6AJYwAD//wGk/zgD6AMgEAsO4AWMAljAAP//AAD/OAJEAyAQCw7iA+gCWMAA//8AAP84AkQDIBALDuED6AJYwAD//wAA/zgCRAMgEAsO4wPoAljAAP//AAD/OAPoAVQQgw7cAMgDIAAAwABAAAAAAAD//wAA/zgD6AF8EIMO3wDIAyAAAMAAQAAAAAAA//8AAP84A+gBfBCDDt4AyAMgAADAAEAAAAAAAP//AAD/OAPoAXwQgw7gAMgDIAAAwABAAAAAAAD//wAA/zgD6AFUEIMO3QDIAyAAAMAAQAAAAAAA//8AAP84A+gBfBCDDuIAyAMgAADAAEAAAAAAAP//AAD/OAPoAXwQgw7hAMgDIAAAwABAAAAAAAD//wAA/zgD6AF8EIMO4wDIAyAAAMAAQAAAAAAA//8AAAEEA+gDIBCDDtwDIP84AABAAMAAAAAAAP/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\ No newline at end of file diff --git a/src/common/FreeSans.json.REMOVED.git-id b/src/common/FreeSans.json.REMOVED.git-id deleted file mode 100644 index faaa8496e6e..00000000000 --- a/src/common/FreeSans.json.REMOVED.git-id +++ /dev/null @@ -1 +0,0 @@ -dd685dbaf617af7c48b6bd0173b54adfde21c435 \ No newline at end of file diff --git a/src/globalStyles/images/cbioportal_logo.png b/src/globalStyles/images/cbioportal_logo.png new file mode 100644 index 00000000000..ca2fe3b4ec4 Binary files /dev/null and b/src/globalStyles/images/cbioportal_logo.png differ diff --git a/src/globalStyles/images/drug.png b/src/globalStyles/images/drug.png new file mode 100644 index 00000000000..c656ded79a9 Binary files /dev/null and b/src/globalStyles/images/drug.png differ diff --git a/src/pages/patientView/clinicalInformation/PatientViewPageStore.ts b/src/pages/patientView/clinicalInformation/PatientViewPageStore.ts index 6f529f91e41..cfa3573d63d 100644 --- a/src/pages/patientView/clinicalInformation/PatientViewPageStore.ts +++ b/src/pages/patientView/clinicalInformation/PatientViewPageStore.ts @@ -1310,7 +1310,11 @@ export class PatientViewPageStore { { await: () => [this.molecularProfilesInStudy], invoke: async () => - findMrnaRankMolecularProfileId(this.molecularProfilesInStudy), + findMrnaRankMolecularProfileId( + this.molecularProfilesInStudy.result!.map( + p => p.molecularProfileId + ) + ), }, null ); diff --git a/src/pages/patientView/patientHeader/images/darwin_logo.png b/src/pages/patientView/patientHeader/images/darwin_logo.png new file mode 100644 index 00000000000..dc503f13541 Binary files /dev/null and b/src/pages/patientView/patientHeader/images/darwin_logo.png differ diff --git a/src/pages/resultsView/expression/expressionHelpers.sample.js b/src/pages/resultsView/expression/expressionHelpers.sample.js new file mode 100644 index 00000000000..4a4dbb13dbd --- /dev/null +++ b/src/pages/resultsView/expression/expressionHelpers.sample.js @@ -0,0 +1,42299 @@ +export const studyData = [ + { + uniqueSampleKey: + 'VENHQS1BQi0yODAzLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2803-03', + patientId: 'TCGA-AB-2803', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1788.21460808472, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODA1LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODA1OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2805-03', + patientId: 'TCGA-AB-2805', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1344.67858067715, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODA2LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODA2OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2806-03', + patientId: 'TCGA-AB-2806', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2540.32735948506, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODA3LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODA3OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2807-03', + patientId: 'TCGA-AB-2807', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1598.9317050419, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODA4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODA4OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2808-03', + patientId: 'TCGA-AB-2808', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2061.40427018172, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODEwLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODEwOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2810-03', + patientId: 'TCGA-AB-2810', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2152.67057918194, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODExLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODExOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2811-03', + patientId: 'TCGA-AB-2811', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 624.24918630397, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODEyLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODEyOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2812-03', + patientId: 'TCGA-AB-2812', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1841.75214610246, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODEzLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODEzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2813-03', + patientId: 'TCGA-AB-2813', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1933.49628137823, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODE0LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODE0OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2814-03', + patientId: 'TCGA-AB-2814', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1683.19457756399, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODE1LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODE1OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2815-03', + patientId: 'TCGA-AB-2815', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2001.90237612469, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODE2LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODE2OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2816-03', + patientId: 'TCGA-AB-2816', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1236.75548752757, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODE3LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODE3OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2817-03', + patientId: 'TCGA-AB-2817', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2343.75827833472, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODE4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODE4OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2818-03', + patientId: 'TCGA-AB-2818', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1315.45888900806, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODE5LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODE5OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2819-03', + patientId: 'TCGA-AB-2819', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2641.11811991005, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODIwLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODIwOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2820-03', + patientId: 'TCGA-AB-2820', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 177.760665663725, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODIxLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODIxOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2821-03', + patientId: 'TCGA-AB-2821', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1975.51232008478, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODIyLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODIyOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2822-03', + patientId: 'TCGA-AB-2822', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1908.97942918316, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODIzLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODIzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2823-03', + patientId: 'TCGA-AB-2823', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1408.09488545273, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODI0LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODI0OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2824-03', + patientId: 'TCGA-AB-2824', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2567.96936244079, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODI1LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODI1OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2825-03', + patientId: 'TCGA-AB-2825', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1383.86669712374, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODI2LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODI2OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2826-03', + patientId: 'TCGA-AB-2826', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1674.01344676103, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODI4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODI4OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2828-03', + patientId: 'TCGA-AB-2828', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2081.51850711245, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODMwLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODMwOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2830-03', + patientId: 'TCGA-AB-2830', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 3174.59718837311, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODMyLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODMyOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2832-03', + patientId: 'TCGA-AB-2832', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2639.71154964626, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODM0LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODM0OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2834-03', + patientId: 'TCGA-AB-2834', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2191.61245353832, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODM1LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODM1OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2835-03', + patientId: 'TCGA-AB-2835', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1632.62606197935, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODM2LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODM2OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2836-03', + patientId: 'TCGA-AB-2836', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1611.06550463004, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODM3LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODM3OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2837-03', + patientId: 'TCGA-AB-2837', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1311.63507520076, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODM4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODM4OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2838-03', + patientId: 'TCGA-AB-2838', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 666.898408595377, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODM5LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODM5OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-2839-03', + patientId: 'TCGA-AB-2839', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1925.63450211081, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0yODQwLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 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+ patientId: 'TCGA-AB-3009', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2044.63983926182, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0zMDExLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0zMDExOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-3011-03', + patientId: 'TCGA-AB-3011', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 2310.5118505363, + }, + { + uniqueSampleKey: + 'VENHQS1BQi0zMDEyLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0zMDEyOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + entrezGeneId: 7157, + molecularProfileId: + 'laml_tcga_pan_can_atlas_2018_rna_seq_v2_mrna_median', + sampleId: 'TCGA-AB-3012-03', + patientId: 'TCGA-AB-3012', + studyId: 'laml_tcga_pan_can_atlas_2018', + value: 1683.52925246819, + }, +]; + +export const showMutations = true; + +export const mutationsKeyedBySampleId = { + VENHQS1BQi0yODIwLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yODIwLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODIwOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2820-03', + patientId: 'TCGA-AB-2820', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: 'genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578181, + endPosition: 7578182, + referenceAllele: 'NA', + proteinChange: 'P223Rfs*4', + mutationType: 'Frame_Shift_Ins', + functionalImpactScore: '[Not Available]', + fisValue: 1.4013e-45, + linkXvar: '[Not Available]', + linkPdb: '[Not Available]', + linkMsa: '[Not Available]', + ncbiBuild: 'GRCh37', + variantType: 'INS', + keyword: 'TP53 truncating', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: 'GCGGCTC', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 223, + proteinPosEnd: 223, + }, + VENHQS1BQi0yODYwLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yODYwLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODYwOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2860-03', + patientId: 'TCGA-AB-2860', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: 'genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7579569, + endPosition: 7579570, + referenceAllele: 'NA', + proteinChange: 'M40Lfs*7', + mutationType: 'Frame_Shift_Ins', + functionalImpactScore: '[Not Available]', + fisValue: 1.4013e-45, + linkXvar: '[Not Available]', + linkPdb: '[Not Available]', + linkMsa: '[Not Available]', + ncbiBuild: 'GRCh37', + variantType: 'INS', + keyword: 'TP53 truncating', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: 'CCATCCAG', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 39, + proteinPosEnd: 40, + }, + VENHQS1BQi0yOTQzLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yOTQzLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yOTQzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2943-03', + patientId: 'TCGA-AB-2943', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: '.;genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577121, + endPosition: 7577121, + referenceAllele: 'G', + proteinChange: 'R273C', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 3.145, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7577121,G,A&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=R273C', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=R273C', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 R273 missense', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: 'A', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 273, + proteinPosEnd: 273, + }, + VENHQS1BQi0yOTM1LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yOTM1LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yOTM1OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2935-03', + patientId: 'TCGA-AB-2935', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: '.;genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577538, + endPosition: 7577538, + referenceAllele: 'C', + proteinChange: 'R248Q', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 2.97, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7577538,C,T&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=R248Q', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=R248Q', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 R248 missense', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: 'T', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 248, + proteinPosEnd: 248, + }, + VENHQS1BQi0yODM4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yODM4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODM4OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2838-03', + patientId: 'TCGA-AB-2838', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: 'genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7579312, + endPosition: 7579312, + referenceAllele: 'C', + proteinChange: 'T125T', + mutationType: 'Splice_Region', + functionalImpactScore: 'NA', + fisValue: 1.4013e-45, + linkXvar: 'NA', + linkPdb: 'NA', + linkMsa: 'NA', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: 'T', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 125, + proteinPosEnd: 125, + }, + VENHQS1BQi0yODg1LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yODg1LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODg1OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2885-03', + patientId: 'TCGA-AB-2885', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: '.;genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578272, + endPosition: 7578272, + referenceAllele: 'G', + proteinChange: 'H193Y', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 2.99, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7578272,G,A&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=H193Y', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=H193Y', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 H193 missense', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: 'A', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 193, + proteinPosEnd: 193, + }, + VENHQS1BQi0yODEzLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yODEzLTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODEzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2813-03', + patientId: 'TCGA-AB-2813', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: '.;genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578403, + endPosition: 7578403, + referenceAllele: 'C', + proteinChange: 'C176Y', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 3.36, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7578403,C,T&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=C176Y', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=C176Y', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 C176 missense', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: 'T', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 176, + proteinPosEnd: 176, + }, + VENHQS1BQi0yOTA4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yOTA4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yOTA4OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2908-03', + patientId: 'TCGA-AB-2908', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: '.;genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578507, + endPosition: 7578507, + referenceAllele: 'G', + proteinChange: 'C141W', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 3.105, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7578507,G,C&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=C141W', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=C141W', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 C141 missense', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: 'C', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 141, + proteinPosEnd: 141, + }, + VENHQS1BQi0yODY4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yODY4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODY4OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2868-03', + patientId: 'TCGA-AB-2868', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: '.;genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578555, + endPosition: 7578555, + referenceAllele: 'C', + proteinChange: 'X126_splice', + mutationType: 'Splice_Site', + functionalImpactScore: 'NA', + fisValue: 1.4013e-45, + linkXvar: 'NA', + linkPdb: 'NA', + linkMsa: 'NA', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 truncating', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: 'T', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 126, + proteinPosEnd: 126, + }, + VENHQS1BQi0yOTM4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yOTM4LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yOTM4OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2938-03', + patientId: 'TCGA-AB-2938', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: '.;genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7574003, + endPosition: 7574003, + referenceAllele: 'G', + proteinChange: 'R342Efs*3', + mutationType: 'Frame_Shift_Del', + functionalImpactScore: 'NA', + fisValue: 1.4013e-45, + linkXvar: 'NA', + linkPdb: 'NA', + linkMsa: 'NA', + ncbiBuild: 'GRCh37', + variantType: 'DEL', + keyword: 'TP53 truncating', + driverFilter: '', + driverFilterAnnotation: '', + driverTiersFilter: '', + driverTiersFilterAnnotation: '', + variantAllele: '-', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 342, + proteinPosEnd: 342, + }, + VENHQS1BQi0yODI5LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + uniqueSampleKey: + 'VENHQS1BQi0yODI5LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + uniquePatientKey: + 'VENHQS1BQi0yODI5OmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg', + molecularProfileId: 'laml_tcga_pan_can_atlas_2018_mutations', + sampleId: 'TCGA-AB-2829-03', + patientId: 'TCGA-AB-2829', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'laml_tcga_pan_can_atlas_2018', + center: '.;genome.wustl.edu', + mutationStatus: 'Somatic', + validationStatus: 'Valid', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577609, + endPosition: 7577609, + referenceAllele: 'C', + proteinChange: 'X225_splice', + mutationType: 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'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 242, + proteinPosEnd: 242, + }, + Q0xMMTYwOmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMTYwOmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMTYwOmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL160', + patientId: 'CLL160', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577556, + endPosition: 7577556, + referenceAllele: 'C', + proteinChange: 'C242F', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 3.345, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7577556,C,A&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=C242F', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=C242F', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 C242 missense', + variantAllele: 'A', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 242, + proteinPosEnd: 242, + }, + Q0xMMDcyOmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMDcyOmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMDcyOmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL072', + patientId: 'CLL072', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578370, + endPosition: 7578370, + referenceAllele: 'C', + proteinChange: 'X187_splice', + mutationType: 'Splice_Site', + functionalImpactScore: 'NA', + fisValue: 1.4013e-45, + linkXvar: 'NA', + linkPdb: 'NA', + linkMsa: 'NA', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 truncating', + variantAllele: 'T', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 187, + proteinPosEnd: 187, + }, + Q0xMMDQyOmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMDQyOmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMDQyOmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL042', + patientId: 'CLL042', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577097, + endPosition: 7577097, + referenceAllele: 'C', + proteinChange: 'D281N', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 3.33, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7577097,C,T&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=D281N', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=D281N', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 D281 missense', + variantAllele: 'T', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 281, + proteinPosEnd: 281, + }, + Q0xMMDkwOmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMDkwOmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMDkwOmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL090', + patientId: 'CLL090', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578208, + endPosition: 7578208, + referenceAllele: 'T', + proteinChange: 'H214R', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 2.305, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7578208,T,C&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=H214R', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=H214R', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 H214 missense', + variantAllele: 'C', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 214, + proteinPosEnd: 214, + }, + Q0xMMDc0OmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMDc0OmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMDc0OmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL074', + patientId: 'CLL074', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7579355, + endPosition: 7579355, + referenceAllele: 'A', + proteinChange: 'L111R', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 2.565, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7579355,A,C&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=L111R', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=L111R', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 L111 missense', + variantAllele: 'C', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 111, + proteinPosEnd: 111, + }, + Q0xMMTQ2OmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMTQ2OmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMTQ2OmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL146', + patientId: 'CLL146', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578265, + endPosition: 7578265, + referenceAllele: 'A', + proteinChange: 'I195T', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 3.08, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7578265,A,G&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=I195T', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=I195T', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 I195 missense', + variantAllele: 'G', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 195, + proteinPosEnd: 195, + }, + Q0xMMDA4OmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMDA4OmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMDA4OmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL008', + patientId: 'CLL008', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577518, + endPosition: 7577518, + referenceAllele: 'T', + proteinChange: 'I255F', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'N', + fisValue: 0.255, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7577518,T,A&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=I255F', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=I255F', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 I255 missense', + variantAllele: 'A', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 255, + proteinPosEnd: 255, + }, + Q0xMMDQxOmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMDQxOmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMDQxOmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL041', + patientId: 'CLL041', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577568, + endPosition: 7577568, + referenceAllele: 'C', + proteinChange: 'C238S', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 3.365, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7577568,C,G&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=C238S', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=C238S', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 C238 missense', + variantAllele: 'G', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 238, + proteinPosEnd: 238, + }, + Q0xMMDc4OmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMDc4OmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMDc4OmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL078', + patientId: 'CLL078', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577141, + endPosition: 7577141, + referenceAllele: 'C', + proteinChange: 'G266V', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 3.3, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7577141,C,A&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=G266V', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=G266V', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 G266 missense', + variantAllele: 'A', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 266, + proteinPosEnd: 266, + }, + Q0xMMDk5OmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMDk5OmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMDk5OmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL099', + patientId: 'CLL099', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578271, + endPosition: 7578271, + referenceAllele: 'T', + proteinChange: 'H193P', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 2.99, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7578271,T,G&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=H193P', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=H193P', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 H193 missense', + variantAllele: 'G', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 193, + proteinPosEnd: 193, + }, + Q0xMMTIwOmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMTIwOmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMTIwOmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL120', + patientId: 'CLL120', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577138, + endPosition: 7577138, + referenceAllele: 'C', + proteinChange: 'R267Q', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 2.6, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7577138,C,T&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=R267Q', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=R267Q', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 R267 missense', + variantAllele: 'T', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 267, + proteinPosEnd: 267, + }, + Q0xMMDQ5OmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMDQ5OmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMDQ5OmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL049', + patientId: 'CLL049', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7578535, + endPosition: 7578537, + referenceAllele: 'TTG', + proteinChange: 'N131del', + mutationType: 'In_Frame_Del', + functionalImpactScore: 'NA', + fisValue: 1.4013e-45, + linkXvar: 'NA', + linkPdb: 'NA', + linkMsa: 'NA', + ncbiBuild: 'GRCh37', + variantType: 'DEL', + keyword: 'TP53 131-131 deletion', + variantAllele: '-', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 131, + proteinPosEnd: 132, + }, + Q0xMMTEwOmxjbGxfYnJvYWRfMjAxMw: { + uniqueSampleKey: 'Q0xMMTEwOmxjbGxfYnJvYWRfMjAxMw', + uniquePatientKey: 'Q0xMMTEwOmxjbGxfYnJvYWRfMjAxMw', + molecularProfileId: 'lcll_broad_2013_mutations', + sampleId: 'CLL110', + patientId: 'CLL110', + entrezGeneId: 7157, + gene: { + entrezGeneId: 7157, + hugoGeneSymbol: 'TP53', + type: 'protein-coding', + cytoband: '17p13.1', + length: 19149, + chromosome: '17', + }, + studyId: 'lcll_broad_2013', + center: 'broad.mit.edu', + mutationStatus: 'Somatic', + validationStatus: 'NA', + tumorRefCount: -1, + normalAltCount: -1, + normalRefCount: -1, + startPosition: 7577587, + endPosition: 7577587, + referenceAllele: 'T', + proteinChange: 'I232F', + mutationType: 'Missense_Mutation', + functionalImpactScore: 'M', + fisValue: 2.42, + linkXvar: 'getma.org/?cm=var&var=hg19,17,7577587,T,A&fts=all', + linkPdb: 'getma.org/pdb.php?prot=P53_HUMAN&from=95&to=289&var=I232F', + linkMsa: 'getma.org/?cm=msa&ty=f&p=P53_HUMAN&rb=95&re=289&var=I232F', + ncbiBuild: 'GRCh37', + variantType: 'SNP', + keyword: 'TP53 I232 missense', + variantAllele: 'A', + refseqMrnaId: + 'NM_001126112.2,NM_001276761.1,NM_001276760.1,NM_000546.5,NM_0011', + proteinPosStart: 232, + proteinPosEnd: 232, + }, +}; + +export const coverageInformation = { + samples: { + VENHQS1BQi0yOTg5LTAzOmxhbWxfdGNnYV9wYW5fY2FuX2F0bGFzXzIwMTg: { + byGene: {}, + allGenes: [ + { + uniqueSampleKey: + 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files /dev/null and b/src/shared/components/query/send-to-gs.png differ diff --git a/src/shared/components/query/styles/jstree/32px.png b/src/shared/components/query/styles/jstree/32px.png new file mode 100644 index 00000000000..67a980ee269 Binary files /dev/null and b/src/shared/components/query/styles/jstree/32px.png differ diff --git a/src/shared/components/query/styles/jstree/40px.png b/src/shared/components/query/styles/jstree/40px.png new file mode 100644 index 00000000000..1959347aea0 Binary files /dev/null and b/src/shared/components/query/styles/jstree/40px.png differ diff --git a/src/shared/lib/StoreUtils.spec.ts b/src/shared/lib/StoreUtils.spec.ts index 349ff81f900..06c5edb133d 100644 --- a/src/shared/lib/StoreUtils.spec.ts +++ b/src/shared/lib/StoreUtils.spec.ts @@ -7,6 +7,7 @@ import { fetchStudiesForSamplesWithoutCancerTypeClinicalData, filterAndAnnotateMolecularData, filterAndAnnotateMutations, + findMrnaRankMolecularProfileId, findSamplesWithoutCancerTypeClinicalData, generateMutationIdByEvent, generateMutationIdByGeneAndProteinChangeAndEvent, @@ -1470,4 +1471,47 @@ describe('StoreUtils', () => { ); }); }); + + describe('findMrnaRankMolecularProfileId', () => { + it('requires `rna_seq` in profile name', () => { + const list = [ + 'ucec_tcga_pub_rppa', + 'ucec_tcga_pub_rppa_Zscores', + 'ucec_tcga_pub_gistic', + 'ucec_tcga_pub_linear_CNA', + 'ucec_tcga_pub_mutations', + 'ucec_tcga_pub_methylation_hm27', + 'ucec_tcga_pub_mrna', + 'ucec_tcga_pub_mrna_median_Zscores', + ',ucec_tcga_pub_mrna_median_all_sample_Zscores', + 'ucec_tcga_pub_rna_seq_v2_mrna', + 'ucec_tcga_pub_rna_seq_v2_mrna_median_Zscores', + 'ucec_tcga_pub_rna_seq_v2_mrna_median_all_sample_Zscores', + ]; + + assert.equal( + findMrnaRankMolecularProfileId(list), + 'ucec_tcga_pub_rna_seq_v2_mrna_median_Zscores' + ); + }); + + it('does not match rppa profiles', () => { + const list = [ + 'brca_tcga_pub_rppa', + 'brca_tcga_pub_rppa_Zscores', + 'brca_tcga_pub_gistic', + 'brca_tcga_pub_mrna', + 'brca_tcga_pub_mrna_median_Zscores', + 'brca_tcga_pub_linear_CNA', + 'brca_tcga_pub_methylation_hm27', + 'brca_tcga_pub_mutations', + 'brca_tcga_pub_mirna', + 'brca_tcga_pub_mirna_median_Zscores', + 'brca_tcga_pub_mrna_merged_median_Zscores', + 'brca_tcga_pub_mrna_median_all_sample_Zscores', + ]; + + assert.equal(findMrnaRankMolecularProfileId(list), null); + }); + }); }); diff --git a/src/shared/lib/StoreUtils.ts b/src/shared/lib/StoreUtils.ts index ea43e8ca6b5..e9319a98e25 100644 --- a/src/shared/lib/StoreUtils.ts +++ b/src/shared/lib/StoreUtils.ts @@ -1109,33 +1109,16 @@ export function findUncalledMutationMolecularProfileId( } export function findMrnaRankMolecularProfileId( - molecularProfilesInStudy: MobxPromise + molecularProfilesInStudy: string[] ) { - if (!molecularProfilesInStudy.result) { - return null; - } - - const regex1 = /^.+rna_seq.*_zscores$/; // We prefer profiles that look like this - const regex2 = /^.*_zscores$/; // If none of the above are available, we'll look for ones like this - const preferredProfile: - | MolecularProfile - | undefined = molecularProfilesInStudy.result.find( - (gp: MolecularProfile) => - regex1.test(gp.molecularProfileId.toLowerCase()) + const regex1 = /^.+rna_seq.*_zscores$/i; // We prefer profiles that look like this + const preferredProfileId: + | string + | undefined = molecularProfilesInStudy.find(profileId => + regex1.test(profileId) ); - if (preferredProfile) { - return preferredProfile.molecularProfileId; - } else { - const fallbackProfile: - | MolecularProfile - | undefined = molecularProfilesInStudy.result.find( - (gp: MolecularProfile) => - regex2.test(gp.molecularProfileId.toLowerCase()) - ); - - return fallbackProfile ? fallbackProfile.molecularProfileId : null; - } + return preferredProfileId || null; } export function generateUniqueSampleKeyToTumorTypeMap( diff --git a/src/shared/lib/data/reference_genome_hg19.json b/src/shared/lib/data/reference_genome_hg19.json new file mode 100644 index 00000000000..59853a1f675 --- /dev/null +++ b/src/shared/lib/data/reference_genome_hg19.json @@ -0,0 +1 @@ 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