diff --git a/src/tox_uv/_venv.py b/src/tox_uv/_venv.py
index cf7e1f2..9e76c4d 100644
--- a/src/tox_uv/_venv.py
+++ b/src/tox_uv/_venv.py
@@ -103,6 +103,14 @@ def environment_variables(self) -> dict[str, str]:
         env["VIRTUAL_ENV"] = str(self.venv_dir)
         return env
 
+    def _default_pass_env(self) -> list[str]:
+        env = super()._default_pass_env()
+        env.append("UV_*")  # accept uv env vars
+        if sys.platform == "darwin":  # pragma: darwin cover
+            env.append("MACOSX_DEPLOYMENT_TARGET")  # needed for macOS binary builds
+        env.append("PKG_CONFIG_PATH")  # needed for binary builds
+        return env
+
     def create_python_env(self) -> None:
         base = self.base_python.version_info
         version_spec = f"{base.major}.{base.minor}" if base.minor else f"{base.major}"
diff --git a/tests/test_tox_uv_venv.py b/tests/test_tox_uv_venv.py
index 54e38c1..1186642 100644
--- a/tests/test_tox_uv_venv.py
+++ b/tests/test_tox_uv_venv.py
@@ -1,6 +1,7 @@
 from __future__ import annotations
 
 import sys
+from configparser import ConfigParser
 from typing import TYPE_CHECKING
 
 if TYPE_CHECKING:
@@ -13,6 +14,21 @@ def test_uv_venv_self(tox_project: ToxProjectCreator) -> None:
     result.assert_success()
 
 
+def test_uv_venv_pass_env(tox_project: ToxProjectCreator) -> None:
+    project = tox_project({"tox.ini": "[testenv]\npackage=skip"})
+    result = project.run("c", "-k", "pass_env")
+    result.assert_success()
+
+    parser = ConfigParser()
+    parser.read_string(result.out)
+    pass_through = set(parser["testenv:py"]["pass_env"].splitlines())
+
+    if sys.platform == "darwin":  # pragma: darwin cover
+        assert "MACOSX_DEPLOYMENT_TARGET" in pass_through
+    assert "UV_*" in pass_through
+    assert "PKG_CONFIG_PATH" in pass_through
+
+
 def test_uv_venv_spec(tox_project: ToxProjectCreator) -> None:
     ver = sys.version_info
     project = tox_project({"tox.ini": f"[testenv]\npackage=skip\nbase_python={ver.major}.{ver.minor}"})