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overall sentence about diagnostic cell type plots
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sjspielman committed Mar 5, 2024
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Expand Up @@ -158,15 +158,16 @@ The workflow directly returns the results from running `spaceranger` without any

<!-- Figure S4 -->
![**Assessment of cell type annotation quality.**](https://raw.githubusercontent.com/AlexsLemonade/scpca-paper-figures/main/figures/compiled_figures/pngs/figure_s4.png?sanitize=true){#fig:figs4 tag="S4" width="7in"}
Both plots in this figure are examples of diagnostic plots in the cell type summary report, shown for library `SCPCL000001`.

A. Diagnostic plot showing `SingleR` cell type annotation quality, shown for library `SCPCL000001`.
A. Diagnostic plot showing `SingleR` cell type annotation quality.
Cell type annotations are shown on the y-axis, the _delta median_ statistic is shown on the x-axis.
The _delta median_ statistic is calculated for each cell as the difference between the `SingleR` score of the annotated cell type label and the median score of all other cell type labels in the reference dataset.
Higher values indicate a higher quality cell type annotation, although there is no absolute scale for these values.
Each black point represents a cell, where closed circles denote cells with high-quality annotations and open circles denote cells with low-quality annotations, as assessed by `SingleR`.
Red diamonds represent the median _delta median_ scores for all cells with high-quality annotations associated with the given cell type label.

B. Diagnostic plot showing `CellAssign` cell type annotation quality, shown for library `SCPCL000001`.
B. Diagnostic plot showing `CellAssign` cell type annotation quality.
Cell type annotations are shown on the y-axis, and the probability of the annotated cell type as calculated by `CellAssign` is shown on the x-axis.
Each row displays probabilities for only the cells associated with the given cell type annotation, and blue line segments show the probabilities for individual cells in each distribution.
Taller line segments are shown for any distribution with five or fewer cells.
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