You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
I noticed that the susie estimated posterior effect sizes are looking very artifactual. For GWAS binary traits some of the estimated posteriors are in the 100's. (example below). The FINEMAP estimates are looking correct. This is either a numerical overflow error or a file parsing error somewhere in the pipeline.
trait region v maf beta se p mean sd prob mean_99
I9_HYPERTROCARDMYOP chr11:54529068-57879829 **11:57537356:G:A** 0.00215164 **2.59323** 0.162437 2.25736e-57 **105.173308070341** 0.160440940543077 1 **105.173308070341**
Marginal estimate is 2.59 and the posterior estimate is 105.17 !!!
The text was updated successfully, but these errors were encountered:
Hi,
I noticed that the susie estimated posterior effect sizes are looking very artifactual. For GWAS binary traits some of the estimated posteriors are in the 100's. (example below). The FINEMAP estimates are looking correct. This is either a numerical overflow error or a file parsing error somewhere in the pipeline.
Marginal estimate is 2.59 and the posterior estimate is 105.17 !!!
The text was updated successfully, but these errors were encountered: