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Automatic Particle Picking, a Low-Effort Cryo-EM Framework

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APPLE Picker

This is the MATLAB version. Check out the Python version of the project.

Also make sure to subscribe to our important updates, tips and tricks about APPLE Picker.

This package contains an implementation of the APPLE particle picker as described in the paper

A. Heimowitz, J. Anden, and A. Singer, "APPLE Picker: Automatic Particle Picking, a Low-Effort Cryo-EM Framework," https://arxiv.org/abs/1802.00469 .

To get started, run the following commands in MATLAB

setup;
getParticles;

This will automatically download two datasets of micrograph and run the APPLE picker on them. The implementation requires the Image Processing Toolbox to be installed. For best performance, it is recommended to run this on a GPU using the Distributed Computing Toolbox.

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