Updating readme to better reflect dev setup process

README.MD

@@ -1,7 +1,26 @@
-## Project Name: geneweaver-api
+# Geneweaver 3 API
 
-Description: description
+Description: The API for the Geneweaver v3 application ecosystem.
 
-App: geneweaver_api
+## Setup
 
-To run the app execute `uvicorn geneweaver_api.main:app --reload`
+### Local
+
+#### Requirements
+
+- Python Poetry
+- Python 3.9 or higher
+- A connection to a copy of the Geneweaver Database
+
+#### Setup
+
+1. Clone the repository
+2. Run `poetry install` in project root to install dependencies
+3. Configure environment settings with environment variables or a `.env` file.
+4. Run the application
+
+To run the app execute either `uvicorn geneweaver.api.main:app --reload` with the poetry
+virtualenv activated, or just run `poetry run uvicorn geneweaver.api.main:app --reload`.
+
+This will host the application on `http://127.0.0.1:8000/` which means the swagger docs
+page is available at `http://127.0.0.1:8000/docs`.