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slobentanzer committed Feb 15, 2024
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4 changes: 2 additions & 2 deletions README.md
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# Output directory containing the formatted manuscript

The [`gh-pages`](https://github.com/biocypher/biochatter-paper/tree/gh-pages) branch hosts the contents of this directory at <https://biocypher.github.io/biochatter-paper/>.
The permalink for this webpage version is <https://biocypher.github.io/biochatter-paper/v/0b6f149728de443d9cb2c24cced7c765da9cff02/>.
The permalink for this webpage version is <https://biocypher.github.io/biochatter-paper/v/e0f5db3e66336eb8747054cb7d32b3c1edce029e/>.
To redirect to the permalink for the latest manuscript version at anytime, use the link <https://biocypher.github.io/biochatter-paper/v/freeze/>.

## Files
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## Source

The manuscripts in this directory were built from
[`0b6f149728de443d9cb2c24cced7c765da9cff02`](https://github.com/biocypher/biochatter-paper/commit/0b6f149728de443d9cb2c24cced7c765da9cff02).
[`e0f5db3e66336eb8747054cb7d32b3c1edce029e`](https://github.com/biocypher/biochatter-paper/commit/e0f5db3e66336eb8747054cb7d32b3c1edce029e).
16 changes: 8 additions & 8 deletions index.html
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<meta name="dc.date" content="2024-02-15" />
<meta name="citation_publication_date" content="2024-02-15" />
<meta property="article:published_time" content="2024-02-15" />
<meta name="dc.modified" content="2024-02-15T10:31:15+00:00" />
<meta property="article:modified_time" content="2024-02-15T10:31:15+00:00" />
<meta name="dc.modified" content="2024-02-15T10:32:05+00:00" />
<meta property="article:modified_time" content="2024-02-15T10:32:05+00:00" />
<meta name="dc.language" content="en-UK" />
<meta name="citation_language" content="en-UK" />
<meta name="dc.relation.ispartof" content="Manubot" />
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<meta name="citation_fulltext_html_url" content="https://biocypher.github.io/biochatter-paper/" />
<meta name="citation_pdf_url" content="https://biocypher.github.io/biochatter-paper/manuscript.pdf" />
<link rel="alternate" type="application/pdf" href="https://biocypher.github.io/biochatter-paper/manuscript.pdf" />
<link rel="alternate" type="text/html" href="https://biocypher.github.io/biochatter-paper/v/0b6f149728de443d9cb2c24cced7c765da9cff02/" />
<meta name="manubot_html_url_versioned" content="https://biocypher.github.io/biochatter-paper/v/0b6f149728de443d9cb2c24cced7c765da9cff02/" />
<meta name="manubot_pdf_url_versioned" content="https://biocypher.github.io/biochatter-paper/v/0b6f149728de443d9cb2c24cced7c765da9cff02/manuscript.pdf" />
<link rel="alternate" type="text/html" href="https://biocypher.github.io/biochatter-paper/v/e0f5db3e66336eb8747054cb7d32b3c1edce029e/" />
<meta name="manubot_html_url_versioned" content="https://biocypher.github.io/biochatter-paper/v/e0f5db3e66336eb8747054cb7d32b3c1edce029e/" />
<meta name="manubot_pdf_url_versioned" content="https://biocypher.github.io/biochatter-paper/v/e0f5db3e66336eb8747054cb7d32b3c1edce029e/manuscript.pdf" />
<meta property="og:type" content="article" />
<meta property="twitter:card" content="summary_large_image" />
<link rel="icon" type="image/png" sizes="192x192" href="https://manubot.org/favicon-192x192.png" />
Expand All @@ -188,9 +188,9 @@ <h1 class="title">A Platform for the Biomedical Application of Large Language Mo
</header>
<p><small><em>
This manuscript
(<a href="https://biocypher.github.io/biochatter-paper/v/0b6f149728de443d9cb2c24cced7c765da9cff02/">permalink</a>)
(<a href="https://biocypher.github.io/biochatter-paper/v/e0f5db3e66336eb8747054cb7d32b3c1edce029e/">permalink</a>)
was automatically generated
from <a href="https://github.com/biocypher/biochatter-paper/tree/0b6f149728de443d9cb2c24cced7c765da9cff02">biocypher/biochatter-paper@0b6f149</a>
from <a href="https://github.com/biocypher/biochatter-paper/tree/e0f5db3e66336eb8747054cb7d32b3c1edce029e">biocypher/biochatter-paper@e0f5db3</a>
on February 15, 2024.
</em></small></p>
<h2 id="authors">Authors</h2>
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To facilitate interfacing with LLMs in the biomedical space, while at the same time safeguarding their functionalities through sensible constraints, we propose a dedicated, open-source framework: BioChatter.
Based on open-source software packages, we synergise the many functionalities that are currently developing around LLMs, such as knowledge integration / retrieval-augmented generation, model chaining, and benchmarking, resulting in an easy-to-use and inclusive framework for application in many use cases of biomedicine.
We focus on robust and user-friendly implementation, including ways to deploy privacy-preserving local open-source LLMs.
We demonstrate use cases via two multi-purpose web apps (https://chat.biocypher.org), and provide documentation, support, and an open community.</p>
We demonstrate use cases via two multi-purpose web apps (<a href="https://chat.biocypher.org">https://chat.biocypher.org</a>), and provide documentation, support, and an open community.</p>
<h2 id="introduction">Introduction</h2>
<p>Despite technological advances, understanding biological and biomedical systems still poses major challenges <span class="citation" data-cites="195HIa77n 1AZn5l2ah">[<a href="#ref-195HIa77n" role="doc-biblioref">1</a>,<a href="#ref-1AZn5l2ah" role="doc-biblioref">2</a>]</span>.
We measure more and more data points with ever-increasing resolution to such a degree that their analysis and interpretation have become the bottleneck for their exploitation <span class="citation" data-cites="1AZn5l2ah">[<a href="#ref-1AZn5l2ah" role="doc-biblioref">2</a>]</span>.
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