This repository includes the complete source code for the Helmholtz Munich Imputation Server, repository forked from the Michigan Imputation Server repository, workflow based on Minimac4. The workflow itself is executed with the Cloudgene workflow system for Hadoop MapReduce.
Helmholtz Munich Imputation Server consists of several parallelized pipeline steps:
- Quality Control
- QC Report
- Phasing and Imputation
- Compression and Encryption
The documentation is available at https://imputationserver-doc.readthedocs.io.
Please cite this paper if you use Helmholtz Munich Imputation Server:
Das S, Forer L, Schönherr S, Sidore C, Locke AE, Kwong A, Vrieze S, Chew EY, Levy S, McGue M, Schlessinger D, Stambolian D, Loh PR, Iacono WG, Swaroop A, Scott LJ, Cucca F, Kronenberg F, Boehnke M, Abecasis GR, Fuchsberger C. Next-generation genotype imputation service and methods. Nature Genetics 48, 1284–1287 (2016).
Feel free to contact us in case of any problems.
- Lukas Forer
- Sebastian Schönherr
- Sayantan Das
- Christian Fuchsberger
- William Rayner
- Andrei Barysenka
- Young-Chan Park