0.6.0-beta
Pre-release
Pre-release
dancooke
released this
10 Feb 18:51
·
1484 commits
to develop
since this release
This release improves calling accuracy, includes more flexible error modelling, and adds annotations to filtered VCF and realigned BAM files.
Interface changes
- The
--training-annotations
option is replaced with--annotations
, with has slightly different behaviour (see below). - The
--split-bamout
option is removed as--bamout
realignments now include tags. - Adds the option
--full-bamout
. [1147e8f] - Adds the option
--refcall-block-merge-threshold
for controlling recall blocks. - Renames
--extract-filtered-source-candidates
to--use-filtered-source-candidates
. [6972ffa]
Improvements
- Indel error models now include variable gap extension penalties and account for tetra-nucleotide tandem repeats. [8f40fc3]
- More built-in sequence error models to choose from, and custom error models (see wiki). [8f40fc3]
- Annotations can now be requested for filtered VCF files using the new
--annotations
option. [c75cbac] - Reference calling now outputs calls in adaptive blocks using the new
--refcall-block-merge-threshold
option. [9127cf3] - Better handling of temporary BCF files in multithreaded mode helps prevent system errors due to too many open files (addresses issue #52). [42fa364]
- Adds annotations to realigned evidence BAMs (see wiki). [c047e96]