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JavaScript Software for Detecting Ca2+ Transient Abnormalities in Cardiomyocytes

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AnomalyExplorer

JavaScript Software for Detecting Ca2+ Transient Abnormalities in Cardiomyocytes

What is it?

The AnomalyExplorer (AE) is a HTML5-based analysis tool for calcium cycling. It is based on the earlier Java implementation described in

Siirtola, H., Àvalos-Salguero, J., Penttinen, K., Aalto-Setälä̈, K., and Juhola, M. (2014). Interactive biosignal analysis and classification. In Information Visualisation (iV2014), 18th International Conference, pages 327–332. (PDF available upon request.)

Basically, AE is a one-page web application implemented mainly in JavaScript. It should run on any modern web browser, but it has been specifically tested with Google Chrome and Safari.

Documentation

Currently, the only documentation is the PLOS-One article. The distribution contains example data files demonstrating the anomaly types that can be detected with AE.

Installation

AE does not require any installation beyond copying the files and the folder structure into a new location. AE does not even require a web server as it can be run from a local copy.

Running the software

Files include test dataset which can be uploaded to AE from “Choose files” function. Suitable control parameter settings for this test dataset are set as default but can be as well controlled by user. Immediately after the test dataset is uploaded to the software, results with the default parameter settings are shown.

Contact

  • For questions related to biomedical aspects of AE, please contact Kirsi Penttinen, [email protected]

  • For questions related to technological aspects of AE, please contact Harri Siirtola, [email protected]

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JavaScript Software for Detecting Ca2+ Transient Abnormalities in Cardiomyocytes

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