Update and Rerun Notice
With this release, we've reached ~100% accuracy of lifted over segments using examples/chain_check.rs
and demonstrated 100% concordance with CrossMap
(https://crossmap.sourceforge.net) over 1,000,000 randomly selected position liftovers. That being said, this release also includes fixes for translations to positions on the negative strand, which is a typically a very small number (~0.1% - 1% of real positions you might want to lift over).
That being said, if you've used chainfile
before to liftover variants before, we highly recommend that you rerun previous liftovers with this version of the crate. The vast majority of liftovers are not expected to change, but liftovers to positions on the negative strand should be corrected.
Added
- Added a new
bin/kitchen_sink.rs
that compares the performance ofchainfile
withCrossMap
(https://crossmap.sourceforge.net).