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RNA-Seq germline variant calling pipeline #123

Merged
merged 57 commits into from
May 3, 2024
Merged

RNA-Seq germline variant calling pipeline #123

merged 57 commits into from
May 3, 2024

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adthrasher
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Add a variant calling pipeline for RNA-Seq. Implements the GATK RNA-Seq short variant discovery best practices workflow (https://gatk.broadinstitute.org/hc/en-us/articles/360035531192-RNAseq-short-variant-discovery-SNPs-Indels-).

Adds an implementation of sambamba in WDL.

@adthrasher adthrasher changed the title Rnaseq variant RNA-Seq germline variant calling pipeline Jan 25, 2024
@adthrasher adthrasher requested a review from a-frantz April 23, 2024 13:31
@adthrasher adthrasher self-assigned this Apr 23, 2024
@adthrasher adthrasher marked this pull request as ready for review April 23, 2024 13:31
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@a-frantz a-frantz left a comment

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I haven't yet looked at the new sambamba file (or anything "below" that in the GH interface). Will get to it today, but not immediately. Wanted to kick off the feedback I did write.

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@adthrasher adthrasher requested a review from a-frantz May 3, 2024 13:55
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@adthrasher adthrasher requested a review from a-frantz May 3, 2024 18:51
@adthrasher adthrasher merged commit 3b0c2b0 into main May 3, 2024
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@adthrasher adthrasher deleted the rnaseq_variant branch May 3, 2024 18:58
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2 participants