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Implement cazyme and substrate detection with multi-threads supported hmmsearch from pyhmmer.
Companion commands dbcanLight-hmmparser (hmmsearch_parser.py) helps to convert conventional hmmer3 output to dbcan format and dbcanLight-subparser (substrate_parser.py) helps to map to the potential substrate (require to search against the substrate hmm porfile).
Rewrite the hmmsearch filtering codes initally written in Perl by Yanbin Yin@NIU to a Python function overlap_filter under hmmsearch_parser.py.
Process and filter hmmsearch hits on-the-fly to prevent the out-of-memory issue for large input files.