152 bug dnam qc pipeline sex check thresholds #284
Add this suggestion to a batch that can be applied as a single commit.
This suggestion is invalid because no changes were made to the code.
Suggestions cannot be applied while the pull request is closed.
Suggestions cannot be applied while viewing a subset of changes.
Only one suggestion per line can be applied in a batch.
Add this suggestion to a batch that can be applied as a single commit.
Applying suggestions on deleted lines is not supported.
You must change the existing code in this line in order to create a valid suggestion.
Outdated suggestions cannot be applied.
This suggestion has been applied or marked resolved.
Suggestions cannot be applied from pending reviews.
Suggestions cannot be applied on multi-line comments.
Suggestions cannot be applied while the pull request is queued to merge.
Suggestion cannot be applied right now. Please check back later.
Description
This pull request will make the sex check in the DNAm preprocessing pipeline more robust against hard coded thresholds, and more adaptable in the long term for changes to the technology.
It does require a certain number of samples basic testing would indicate at least 20, and is designed for the situation where you have at least two sexes present in the data. While I have tried to account for a single sex dataset, I have not been able to test this. Equally the behaviour in this situation might require some further consideration.
Issue ticket number
This pull request is to address issue: #152 .
Type of pull request
Checklist